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Sample records for chai minhua jiang

  1. The Historical Thought of Jiang Mengyin

    Institute of Scientific and Technical Information of China (English)

    于文杰[1; Xu Sangyi[2

    2016-01-01

    Jiang Mengyin (蒋孟引) (1907–1988), originally named Jiang Deheng (蒋德恒), also known as Baihuan (百幻),was a renowned Chinese historian. He was born in 1907 at Changping Village, Gaoqiao Town, Xinning County, Hunan Province. Studying in an old–style private school in his youth, Jiang showed his talents and special interests in history, as he frequently discussed historical issues with his tutor and formulated his own opinions. He then took historical research as his life–long pursuit. In 1928, Jiang was enrolled in the Department of History at National Central University.

  2. A Decade of Chais Conferences: Introduction to the IJELL Special Series of Chais Conference 2015 Best Papers

    Directory of Open Access Journals (Sweden)

    Nitza Geri

    2015-12-01

    This preface presents the mission and activities of the Research Center for Innovation in Learning Technologies at the Open University of Israel. It describes the objectives and themes of the Chais conference 2015, explains the special series synergies with IJELL and the Informing Science Institute, chronicles the topics that have been published in the series, and introduces the papers included in this special selection.

  3. Seasonal variation of organic matter concentration and characteristics in the Maji ya Chai River (Tanzania): Impact on treatability by ultrafiltration

    KAUST Repository

    Aschermann, Geert; Jeihanipour, Azam; Shen, Junjie; Mkongo, Godfrey; Dramas, Laure; Croue, Jean-Philippe; Schä fer, Andrea

    2016-01-01

    The Tanzanian river Maji ya Chai was sampled monthly during one year. The composition of NOM in Maji ya Chai River is influenced strongly by precipitation. Total organic carbon (TOC), specific ultraviolet absorbance (SUVA

  4. Jiang Shuqin: a devoted family planning worker.

    Science.gov (United States)

    Zhu, H

    1997-04-01

    This article describes the family planning activities of a barefoot doctor, Jiang Shuqin, who has delivered family planning and other medical services to poor local farmers in China over the past 20 years. The once backward township of Kulongshan in Fengning Manchu Nationality Autonomous County, Chengde City, Hebei Province in North China, where she works, has advanced. Her efforts were recognized at the 1997 National Conference on Family Planning Work. Her first success was in treating a poor woman's sick child, which resulted in such gratitude that her initial reluctance to accept contraception was overcome and she agreed to terminate her pregnancy. Another case involved an elder sister who became pregnant for her infertile sister; when the latter was diagnosed and treated for gynecological disease and subsequently conceived herself, the older sister was convinced to abort her pregnancy. One woman was counseled to delay a pregnancy until treatment for tuberculosis was completed and was happy to avoid birth defects and enjoyed having a healthy baby 3 years later. Ms. Shuqin was known to quickly respond to a home delivery and difficult labor and even saved a baby whose supply of oxygen was limited during a difficult labor. She even performed an operation to stop massive hemorrhaging from a retained placenta while in her 8th month of pregnancy and being barely able to stand on her swollen and painful legs; she completed the operation on her knees. She wrote a paper to county officials on rice production on reclaimed paddy fields that benefitted hundreds of farmers. Her practice expanded to include treatment of animals. Her family complains about her absences, but everyone in the township appreciates her services. The township is proud to be one with no unplanned births.

  5. Occurrence of chai hu (Bupleuri radix) in prescriptions of Chinese herbal medicine in Switzerland.

    Science.gov (United States)

    Klein, Sabine D; Becker, Simon; Wolf, Ursula

    2012-01-01

    Chai hu (Bupleuri radix), one of the most frequently used herbs in Chinese herbal medicine, has 3 major functions, depending on dosage and combination with other herbs. The aim of this study was to investigate how chai hu is prescribed in everyday practice in Switzerland, and whether these prescription patterns reflect its various applications. A random sample of 1,053 prescriptions was drawn from the database of Lian Chinaherb AG, Wollerau, Switzerland, and analyzed regarding the most frequently used classical formulas containing chai hu, daily dosages and combinations with other herbs. 29.0% of all prescriptions contained chai hu, and 98.0% of these were in granular form. The most frequently used classical formulas were xiao yao san ('rambling powder'), jia wei xiao yao san ('augmented rambling powder') and chai hu shu gan san ('Bupleurum powder to spread the liver'). In more than half of the prescriptions, chai hu was combined with bai shao (Paeoniae Radix Alba), dang gui (Angelicae sinensis radix) or fu ling (Poria). 51.8% of the prescriptions contained a low daily dosage of chai hu, 24.9% a medium and 15.1% a high dosage. Chai hu was generally prescribed in classic combinations with other herbs and in a medium dosage. Due to the addition of supplementary herbs to classical formulas, its daily dose was often diminished from a high or medium dose to a low dose. This raises the question if chai hu would then still exert its desired function of, e.g., moving liver-qi in these prescriptions.

  6. An experimental study of mechanism in treatment for endometriosis with Xiao Chai Hu Tang in rats

    International Nuclear Information System (INIS)

    Zhang Hui; Zuo Liandong; Li Hongyi

    2005-01-01

    To explore the mechanism of Xiao Chai Hu Tang in treatment for endometriosis in rats, the rat model of endometriosis was established. Using immunohistochemistry method, Fas and Caspase-3 protein expression in endometrium and endometriotic tissue of each group were observed. The results showed that in the group treated with Xiao Chai Hu Tang, the protein expressions of Fas and Caspase-3 in endometriotic tissue were higher than those in endometrium, while in the control group, the result was just opposite. The difference was not obvious in the group treated with Danazol . The higher levels of the protein expression of Fas in endometriotic tissue may related to the pathogenesis of the endometriosis. The mechanism of Xiao Chai Hu Tang treatment may be partly to increase apoptosis in endometriotic tissue. (authors)

  7. Metaproteomics of Microbiota in Naturally Fermented Soybean Paste, Da-jiang.

    Science.gov (United States)

    Zhang, Ping; Zhang, Pengfei; Xie, Mengxi; An, Feiyu; Qiu, Boshu; Wu, Rina

    2018-05-01

    Da-jiang is a typical traditional fermented soybean product in China. At present, the proteins in da-jiang are needed to be explored. The composition and species of microbial proteins in traditional fermented da-jiang were analyzed by metaproteomics based on sodium dodecyl sulfonate-polyacrylamide gel electrophoresis (SDS-PAGE) and liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). The results showed that the number and variety of microbial proteins in the traditional fermented da-jiang from different regions were different. The production site influences the fermentation in da-jiang. Then we analyzed the functions of the microbial proteins identified in da-jiang, and found that they were mainly involved in the process of protein synthesis, glycometabolism and nucleic acid synthesis. In addtion, we compared the proteins composition in different da-jiang. There are 51 common proteins of naturally fermented da-jiang, and 25 common microbial sources. The main commonly microbial sources of fungal proteins are Saccharomyces cerevisiae and Schizosaccharomyces; the main commonly microbial sources of bacterial proteins are Enterococcus faecalis, Leuconostoc mesenteroides, Acinetobacter baumannii, and Bacillus subtilis. These common microbes play the predominant role in da-jiang fermentation. The present results help us to understand the fermentation of da-jiang and improve the quality and safety of final products in the future. The study illustrated metaproteome of microbiota in traditional fermented soybean paste, da-jiang, by sodium dodecyl sulfonate-polyacrylamide gel electrophoresis (SDS-PAGE) and liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS). A method of extracting metaproteome from microbiota in da-jiang was attempted. The findings help to understand the fermentation of da-jiang and improve the quality and safety of da-jiang in fermented industry. © 2018 Institute of Food Technologists®.

  8. The herbal mixture Xiao-Chai-Hu Tang (XCHT) induces apoptosis of ...

    African Journals Online (AJOL)

    Background: Xiao-Chai-Hu Tang (XCHT) is an extract of seven herbs with anticancer properties, but its mechanism of action is unknown. In this study, we evaluated XCHT-treated hepatocellular carcinoma (HCC) for anti-proliferative and pro-apoptotic effects. Materials and Methods: Using a hepatic cancer xenograft model, ...

  9. Bulb turbine operating at medium head: XIA JIANG case study

    International Nuclear Information System (INIS)

    Loiseau, F; Desrats, C; Petit, P; Liu, J

    2012-01-01

    With lots of references for 4-blade bulb turbines, such as these of Wu Jin Xia (4 units – 36.1 MW per unit – 9.2 m rated head), Chang Zhou (15 units – 46.7 MW per unit – 9.5 m rated head) and Tong Wan (4 units – 46.2 MW per unit – 11 m rated head), ALSTOM Power Hydro is one of the major suppliers of bulb turbines operating under medium head for the Chinese market. ALSTOM Power Hydro has been awarded in November 2010 a contract by Jiang Xi Province Xia Jiang Water Control Project Headquarters to equip Xia Jiang's new hydropower plant. The power dam is located on the Gan Jiang river, at about 160 km away from Nan Chang town in South Eastern China. The supply will consist in 5 bulb units including the furniture of both the turbine and its generator, for a total capacity of 200 MW, under a rated net head of 8.6 m. The prototype turbine is a 7.8 m diameter runner, rotating at 71.4 rpm speed. For this project, ALSTOM has proposed a fully new design of 4-blade bulb runner. This paper outlines the main steps of the hydraulic development. First of all, a fine tuning of the blade geometry was performed to enhance the runner behaviour at high loads and low heads, so that to fulfill the demanding requirements of efficiencies and maximum output. The challenge was also to keep an excellent cavitation behaviour, especially at the outer blade diameter in order to avoid cavitation erosion on the prototype. The shape of the blade was optimized by using the latest tools in computational fluid dynamics. Steady state simulations of the distributor and the runner were performed, in order to simulate more accurately the pressure fields on the blade and the velocity distribution at the outlet of the runner. Moreover, draft tube computations have been performed close to the design point and at higher loads. Then, a model fully homologous with the prototype was manufactured and tested at ALSTOM's laboratory in Grenoble (France). The model test results confirmed the predicted

  10. Bulb turbine operating at medium head: XIA JIANG case study

    Science.gov (United States)

    Loiseau, F.; Desrats, C.; Petit, P.; Liu, J.

    2012-11-01

    With lots of references for 4-blade bulb turbines, such as these of Wu Jin Xia (4 units - 36.1 MW per unit - 9.2 m rated head), Chang Zhou (15 units - 46.7 MW per unit - 9.5 m rated head) and Tong Wan (4 units - 46.2 MW per unit - 11 m rated head), ALSTOM Power Hydro is one of the major suppliers of bulb turbines operating under medium head for the Chinese market. ALSTOM Power Hydro has been awarded in November 2010 a contract by Jiang Xi Province Xia Jiang Water Control Project Headquarters to equip Xia Jiang's new hydropower plant. The power dam is located on the Gan Jiang river, at about 160 km away from Nan Chang town in South Eastern China. The supply will consist in 5 bulb units including the furniture of both the turbine and its generator, for a total capacity of 200 MW, under a rated net head of 8.6 m. The prototype turbine is a 7.8 m diameter runner, rotating at 71.4 rpm speed. For this project, ALSTOM has proposed a fully new design of 4-blade bulb runner. This paper outlines the main steps of the hydraulic development. First of all, a fine tuning of the blade geometry was performed to enhance the runner behaviour at high loads and low heads, so that to fulfill the demanding requirements of efficiencies and maximum output. The challenge was also to keep an excellent cavitation behaviour, especially at the outer blade diameter in order to avoid cavitation erosion on the prototype. The shape of the blade was optimized by using the latest tools in computational fluid dynamics. Steady state simulations of the distributor and the runner were performed, in order to simulate more accurately the pressure fields on the blade and the velocity distribution at the outlet of the runner. Moreover, draft tube computations have been performed close to the design point and at higher loads. Then, a model fully homologous with the prototype was manufactured and tested at ALSTOM's laboratory in Grenoble (France). The model test results confirmed the predicted ones: the

  11. Acute Hepatitis Induced by Chinese Hepatoprotective Herb, Xiao-Chai-Hu-Tang

    Directory of Open Access Journals (Sweden)

    Li-Ming Hsu

    2006-02-01

    Full Text Available Xiao-chai-hu-tang (syo-saiko-to in Japanese is a herbal remedy that has been widely used in China for treatment of respiratory, hepatobiliary, and gastrointestinal diseases, particularly among patients with chronic liver disease. However, its safety has recently been challenged. We, herein, report a Chinese patient with acute hepatitis induced by this herb. A 52-year-old woman presented with weakness, fatigue, and tea-colored urine after continual consumption of the decoction of xiao-chai-hu-tang for 1.5 months. Laboratory studies disclosed acute hepatitis even though all of the viral hepatitis markers were negative. Liver biopsy also revealed a picture of acute hepatocellular hepatitis. The symptoms improved after discontinuing the drug, and liver biochemical tests normalized 2 months later. The case report reminds us of the probable adverse drug reaction of herbs, even in some that are claimed to have hepatoprotective effects.

  12. Memory Consolidation of Attended Information Is Optional: Comment on Jiang et al. (2016)

    Science.gov (United States)

    Wyble, Brad; Chen, Hui

    2017-01-01

    Attribute amnesia is a phenomenon in which information about a stimulus that was just recently used to perform a task is poorly remembered in a surprise test (Chen & Wyble, 2015a). In a recent article by Jiang, Shupe, Swallow, and Tan (2016), this effect was replicated but with an additional priming measure that revealed some carryover memory…

  13. Treatment of depression with Chai Hu Shu Gan San: a systematic review and meta-analysis of 42 randomized controlled trials.

    Science.gov (United States)

    Sun, Yan; Xu, Xia; Zhang, Jinping; Chen, Yuanyuan

    2018-02-17

    Depression is a common mental disorder. Chai Hu Shu Gan San, a traditional Chinese medicine, is used to treat depression empirically. We present a systematic review and meta-analysis of the therapeutic efficacy and safety of Chai Hu Shu Gan San in treating depression. Several databases, including PubMed, China National Knowledge Internet, Wanfang, Chongqing VIP, and the Cochrane library, were systematically searched from their date of foundation to January 1, 2017. In this review, wehave included randomized control trials that compared Chai Hu Shu Gan San (or its combination with a regular Western medicine) with a regular Western medicine alone for the treatment of depression. Two investigators independently extracted and analyzed the data using RevMan 5.2.0 software. Mean difference (with a 95% confidence interval) was used as efficacy indices for outcomes. We included 42 studies involving 3234 patients with depression in 15 different types of diseases. Meta analyses showed better effect of Chai Hu Shu Gan San than fluoxetine for pure depression (MD = - 1.59, from - 2.82 to - 0.37, 4 trials, I 2  = 26%), for post-stroke depression (MD = - 4.20, from - 6.20 to - 2.19, 7 trials, I 2  = 96%), and for postpartum depression (MD = - 4.10, from - 7.48 to - 0.72 7 trials, I 2  = 86%). None of the articles reported severe adverse events of oral administration of Chai Hu Shu Gan San. Furthermore, any adverse effects of using Chai Hu Shu Gan San alone were fewer than those of regular Western medicines. This review found that Chai Hu Shu Gan San has some advantages in treating depression, especially post-stroke depression and post-partum depression. A meticulously designed and conducted randomized control trial is needed for further evaluation.

  14. Seasonal variation of organic matter concentration and characteristics in the Maji ya Chai River (Tanzania): Impact on treatability by ultrafiltration

    KAUST Repository

    Aschermann, Geert

    2016-05-07

    Many waters in Tanzania exhibit high concentrations of organic matter and dissolved contaminants such as fluoride. Due to bacteria and virus removal, ultrafiltration (UF) is an attractive option for drinking water treatment, and when coupled with adsorbents, may compete with other established processes like nanofiltration (NF) for lower contaminant concentrations. The results presented here examine the characteristics and treatability of tropical natural organic matter (NOM) by UF as a function of seasonal variation. The Tanzanian river Maji ya Chai was sampled monthly during one year. The composition of NOM in Maji ya Chai River is influenced strongly by precipitation. Total organic carbon (TOC), specific ultraviolet absorbance (SUVA) and concentration of allochthonous organics substances (such as humic substances (HS)) are elevated in periods following high precipitation, while TOC is lower and contains more biopolymers in the dry seasons. UF experiments with two regenerated cellulose membranes of different molecular weight cut-off (MWCO, 5 and 10 kDa) were conducted. UF is able to remove 50–95% of TOC with a seasonal variability of 10–20%. Due to the remaining NOM in the water that would contribute to disinfection by-product formation and bacterial regrowth, the physically disinfected water is more applicable for point of use systems than distribution or storage.

  15. Construction Strategies of Social Security System for Wan-jiang Urban Belt’s Migrant Workers

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Theoretical debate and practice exploration on social security of migrant workers were introduced.The political direction and security layer on social security for migrant workers in Wan-jiang urban belt were analyzed:the first layer is to implement wage payment guarantee and employment injury insurance;the second layer is to emphasize serious disease insurance and endowment insurance;the third layer is unemployed insurance and social assistance.The primary strategy of building a social security system for migrant workers in Wan-jiang urban belt was put up:wage payment guarantee system that is united in certain regions should be promoted;employment injury insurance system that is undertaken by enterprises should be built;a social health care system for serious diseases should be set up;multi-layers endowment insurance system for migrant workers should be created;vocational training and training in how to start a business should be built as well as the unemployment insurance system;social assistant system based on the basic cost of living allowances should be set up.

  16. Case 3. "Jiang Tao v. Chengdu Branch, People's People's Bank of China": Opinion by the People's Court in Wuhou District, Chengdu, Sichuan Province

    Science.gov (United States)

    Chinese Education and Society, 2006

    2006-01-01

    This article presents the decision of the People's Court in Wuhou District, Chengdu, Sichuan Province on the Jiang Tao v. Chengdu Branch, People's People's Bank of China case. Jiang Tao, the plaintiff, claimed that the defendant Chengdu Branch placed an announcement in the "Chengdu Business Daily" to "recruit tellers for Chengdu…

  17. « Comme à l’époque de Suzie Wong ». Les mutations du red-light district de Wan Chai

    OpenAIRE

    Paris, Nicolas

    2011-01-01

    Le roman exotique Le monde de Suzie Wong et ses nombreuses adaptations immortalisent le red-light district de Wan Chai à Hong Kong à la fin des années 1950, mettant en scène marins américains, expatriés de l’Empire britannique et prostituées hongkongaises. Aujourd’hui, avec la mondialisation, Wan Chai est fréquenté par des migrantes de plusieurs pays d’Asie du Sud-Est. Pourtant, le red-light district est toujours associé dans la presse et les guides de voyage à « l’époque de Suzie Wong ». Ces...

  18. Renal Protective Effect of Xiao-Chai-Hu-Tang on Diabetic Nephropathy of Type 1-Diabetic Mice

    Directory of Open Access Journals (Sweden)

    Chun-Ching Lin

    2012-01-01

    Full Text Available Xiao-Chai-Hu-Tang (XCHT, a traditional Chinese medicine formula consisting of seven medicinal plants, is used in the treatment of various diseases. We show here that XCHT could protect type-1 diabetic mice against diabetic nephropathy, using streptozotocin (STZ-induced diabetic mice and high-glucose (HG-exposed rat mesangial cell (RMC as models. Following 4 weeks of oral administration with XCHT, renal functions and renal hypertrophy significantly improved in the STZ-diabetic mice, while serum glucose was only moderately reduced compared to vehicle treatment. Treatment with XCHT in the STZ-diabetic mice and HG-exposed RMC resulted in a decrease in expression levels of TGF-β1, fibronectin, and collagen IV, with concomitant increase in BMP-7 expression. Data from DPPH assay, DHE stain, and CM-H2DCFDA analysis indicated that XCHT could scavenge free radicals and inhibit high-glucose-induced ROS in RMCs. Taken together, these results suggest that treatment with XCHT can improve renal functions in STZ-diabetic mice, an effect that is potentially mediated through decreasing oxidative stress and production of TGF-β1, fibronectin, and collagen IV in the kidney during development of diabetic nephropathy. XCHT, therefore merits further investigation for application to improve renal functions in diabetic disorders.

  19. Analyzing the Discourse of Chais Conferences for the Study of Innovation and Learning Technologies via a Data-Driven Approach

    Directory of Open Access Journals (Sweden)

    Vered Silber-Varod

    2016-12-01

    Full Text Available The current rapid technological changes confront researchers of learning technologies with the challenge of evaluating them, predicting trends, and improving their adoption and diffusion. This study utilizes a data-driven discourse analysis approach, namely culturomics, to investigate changes over time in the research of learning technologies. The patterns and changes were examined on a corpus of articles published over the past decade (2006-2014 in the proceedings of Chais Conference for the Study of Innovation and Learning Technologies – the leading research conference on learning technologies in Israel. The interesting findings of the exhaustive process of analyzing all the words in the corpus were that the most commonly used terms (e.g., pupil, teacher, student and the most commonly used phrases (e.g., face-to-face in the field of learning technologies reflect a pedagogical rather than a technological aspect of learning technologies. The study also demonstrates two cases of change over time in prominent themes, such as “Facebook” and “the National Information and Communication Technology (ICT program”. Methodologically, this research demonstrates the effectiveness of a data-driven approach for identifying discourse trends over time.

  20. [Analysis of clinical characteristics of traditional Chinese and Western medicine in Professor Jiang Liangduo's theory of "sanjiao meridian stasis"].

    Science.gov (United States)

    Wang, Hai-Yan; Jiang, Liang-Duo; Ma, Qing; Xu, Dong; Tang, Shi-Huan; Luo, Zeng-Gang

    2017-12-01

    In the clinical practice, Professor Jiang Liangduo, a national senior Chinese medicine doctor, has created the theory of "sanjiao meridian stasis" from the theory of meridian dialectics and from the overall state. In this paper, the traditional Chinese medicine and Western medicine clinical characteristics of sanjiao meridian stasis theory which is often used by Professor Jiang Liangduo in the treatment of out-patient syndrome differentiation, were first studied and summarized to investigate its inherent regularity. First, the source of data and research methods were introduced, and then the Traditional Chinese Medicine Inheritance Support System was used with the method of data mining to retrospectively analyze the disease characteristics of Chinese and Western medicine in 279 patients with sanjiao meridian stasis diagnosed by Professor Jiang in 2014. Then the following main conclusions were made after research: sanjiao meridian stasis was more common in women as well as young and middle-aged population. Often manifested by prolonged treatment course, red tongue with yellowishfur, with good correlation between modern Western medicine diagnosis and TCM differentiation syndrome. The symptoms of sanjiao meridian stasis syndrome are mostly of heat syndromes, and middle-aged patients are the most common patients with stasis and stasis of sanjiao. Related information of Western medicine diagnosis can help to diagnose the "sanjiao meridian stasis". Copyright© by the Chinese Pharmaceutical Association.

  1. Diagenetic differences of the Zhenzhuchong Member of Ziliujing Formation in the Jiulongshan–Jiange area, Sichuan Basin

    Directory of Open Access Journals (Sweden)

    Mingcai Hou

    2015-03-01

    Full Text Available The rocks of the Zhenzhuchong Member of the Ziliujing Formation, Jiulongshan–Jiange area in the Sichuan Basin, were analyzed by petrography, XRD, and SEM techniques to investigate their diagenetic history and properties, such as authigenic mineral types, evolution of mixed-layer illite–smectite minerals, the clay assembly, and the fraction of mixed-layer clay minerals. The results revealed that the Zhenzhuchong Member has experienced several important episodes of diagenetic alteration since the deposition, including compaction (pressure-solution, cementation, metasomatism, dissolution, fracturing, and infilling of caves and cracks. It was also observed that diagenetic properties of the Jiulongshan area were significantly different from those of the Jiange area. The rock samples from the Jiulongshan area were characterized by the composition of siliceous and calcareous cements, varying amounts of detrital grains, clay matrix and kaolinite replaced by calcites, a certain amount of rarely dissolved early-stage kaolinite, dickite, and infillings by late-stage calcite. On the other hand, for the rock samples from the Jiange area, the dissolution is a common phenomenon with features of abundant aluminosilicates-dissolution pores or components, but the replacement phenomenon has rarely been seen. These rock samples were characterized by the presence of clay mineral cements, quartz, and dolomite infillings. It indicated that there was a great difference of diagenesis between the two areas in the types, phase, and temperature of diagenetic fluids. Revealing the difference would provide theoretical and practical implications for the exploration of high quality oil and gas reservoirs.

  2. Land cover of oases and forest in XinJiang, China retrieved from ASTER data

    Science.gov (United States)

    Buhe, Aosier; Tsuchiya, K.; Kaneko, M.; Ohtaishi, N.; Halik, Mahmut

    ASTER aboard NASA’s satellite Terra is a high-resolution multispectral radiometer of 14 bands. The spatial resolution is 15 m in VNIR, 30 m in SWIR and 90 m in TIR spectra, respectively. With the data observed with ASTER, the land cover classification is produced for the Tarim Diversifolious Poplar Protection Area along the Tarim River in the northern Tarim Basin (Taklamakan Desert) in XinJiang, China. The classification of the vegetation (plants) in the arid and semiarid regions using remote-sensing technology is very difficult. Because the cause has low vegetable cover density and the influence of reflection from background soil is large. ASTER data are effective in studying the spectrum characteristics of land cover in arid and semiarid regions. The sensor has several bands in the shortwave infrared wavelength region that is designed for exploration of earth resources and study of the arid and semiarid region natural environment. However, we are not clear combination of which band is the most effective in research of the arid region like the Taklamakan desert in the data of 14 bands of ASTER. The optimum index factor (OIF), based on total variance within bands and correlation coefficient between bands, is a statistical approach to rank all possible three-band combinations. In the process of analyzing the data, the pixel sizes of all the data are converted (layer stacking and re-sampling) into consistent same size of 15 m. The three-band composite with the largest OIF value will have most information (as measured by variance) with the least amount of duplication (as measured by correlation). We used the OIF technique to rank all three-band combinations of ASTER original 14-band data over Tarim River Poplar Protection Area. Our study indicates that RGB color overlay using atmospheric corrected ASTER original bands 2, 3 (VNIR), and 6 (SWIR) has the highest OIF. When NDVI is considered as one ASTER band, highest OIF will have by carrying out bands 3 (VNIR), 4

  3. [Analyze prescription rules of Professor Jiang Liangduo treatment for abdominal mass based on traditional Chinese medicine inheritance platform].

    Science.gov (United States)

    Lian, Xiao-Xiao; Guo, Xiao-Xia

    2018-01-01

    To investigate the herbal prescription rules of Professor Jiang Liangduo in the treatment of abdominal mass based on the traditional Chinese medicine inheritance support system software (TCMISS) of version 2.5, find out new herbal formulas for the treatment of abdominal mass, and then provide new reference to its traditional Chinese medicine therapy. By the method of retrospective study, one hundred and thirty-two outpatient prescriptions of Professor Jiang for the treatment of abdominal mass were collected to establish a typical database with TCMISS. Four properties, five tastes, channel tropism, frequency count, Chinese herbal prescriptions rules and the new prescriptions were analyzed so as to dig out the prescription rules. There were 57 herbs with a frequency>=15, and then 91 core combinations of 2-5 herbs were evolved and 9 new prescriptions were created. It was found out that these drugs mainly had the effects of liver nourishing and soothing, soft-moist and dredging-tonifying, supporting right and dispeling evil, cooperating with the method of calming the liver and resolving hard lump according to the actual situation. It reflected the thought of treatment based on syndrome differentiation in TCM, and provided a new reference for its clinical treatment and research. Copyright© by the Chinese Pharmaceutical Association.

  4. Lipid-lowering and antioxidant activities of Jiang-Zhi-Ning in Traditional Chinese Medicine.

    Science.gov (United States)

    Chen, Jianxin; Zhao, Huihui; Yang, Ying; Liu, Bing; Ni, Jian; Wang, Wei

    2011-04-12

    Jiang-Zhi-Ning (JZN) is composed of four Chinese herbs, i.e., Fleeceflower Root, Fructus Crataegi, Folium Nelumbinis and Semen Cassiae. It was used to strengthen blood circulation of coronary artery, arrhythmia and hyperlipidemia. The main objective of this paper is to evaluate lipid-lowering and antioxidant activities of extract and effective fraction of JZN by using in vitro experiments on hyperlipidemic rats. Moreover, in vivo experiments on cells were performed to investigate lipid-lowering and antioxidant activities of effective fraction and active constituents of JZN. Wistar rats with high fat diet-induced hyperlipidemia were used as in vitro models to study biological effects of lipid-lowering and antioxidant activities of extract and effective fraction of JZN. Serum total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), Coronary Index and Atherogenic Index were investigated to evaluate lipid-lowering effects of extract and effective fraction of JZN. Serum total nitric oxide synthase (NOS), nitric oxide (NO), endothelin-1 (ET-1), malondialdehyde (MDA), superoxide dismutase (SOD) and total antioxidant capacity (T-AOC) were detected to measure antioxidant effects of extract and effective fraction of JZN. Furthermore, oxidized low-density lipoprotein (Ox-LDL) injured human umbilical vein endothelial cell (HUVEC) model was employed as in vivo experiment to study lipid-lowering and antioxidant effects of effective fraction and active constituents of JZN. NO, ET-1, MDA SOD and T-AOC in HUVECs or culture media were investigated to evaluate antioxidant activity of effective fraction and active constituents of JZN. Using human hepatoma cell line Bel-7402, reverse transcription polymerase chain reaction (RT-PCR) technology was performed to investigate cholesterol metabolism effects of effective fraction and active constituents of JZN. Expressions of low density lipoprotein receptor (LDL

  5. Origin of stratiform sediment-hosted manganese carbonate ore deposits: Examples from Molango, Mexico, and TaoJiang, China

    Science.gov (United States)

    Okita, P.M.; Shanks, Wayne C.

    1992-01-01

    Carbonate and sulfide minerals from the Molango, Mexico, and TaoJiang, China, Mn deposits display similar and distinctive ??34S and ??13C patterns in intervals of manganese carbonate mineralization. ??13C-values for Mn-bearing carbonate range from -17.8 to +0.5??? (PDB), with the most negative values occurring in high-grade ore zones that are composed predominantly of rhodochrosite. In contrast, calcite from below, within and above Mn-carbonate zones at Molango has ??13C???0??? (PDB). Markedly negative ??13C data indicate that a large proportion of the carbon in Mn-carbonates was derived from organic matter oxidation. Diagenetic reactions using MnO2 and SO2-4 to oxidize sedimentary organic matter were the principle causes of such 12C enrichment. Pyrite content and sulfide ?? 34S-values also show distinctive variations. In unmineralized rocks, very negative ??34S-values (avg. < -21??? CDT) and abundant pyrite content suggest that pyrite formed from diagenetic, bacteriogenic sulfate reduction. In contrast, Mn-bearing horizons typically contain only trace amounts of pyrite (e.g., <0.5 wt% S with ??34S-values 34S-enriched, in some cases to nearly the value for contemporaneous seawater. 34S-enriched pyrite from the Mn-carbonate intervals indicates sulfide precipitation in an environment that underwent extensive SO2-4 reduction, and was largely a closed system with regard to exchange of sulfate and dissolved sulfide with normal seawater. The occasional occurrence of 34S-depleted pyrite within Mn-carbonate zones dominated by 34S-enriched pyrite is evidence that closed-system conditions were intermittent and limited to local pore waters and did not involve entire sedimentary basins. Mn-carbonate precipitation may have occluded porosity in the surficial sediments, thus establishing an effective barrier to SO2-4 exchange with overlying seawater. Similar isotopic and mineralogic characteristics from both the Molango and TaoJiang deposits, widely separated in geologic time and

  6. Serum metabonomics study of anti-depressive effect of Xiao-Chai-Hu-Tang on rat model of chronic unpredictable mild stress.

    Science.gov (United States)

    Xiong, Zhili; Yang, Jie; Huang, Yue; Zhang, Kuo; Bo, Yunhai; Lu, Xiumei; Su, Guangyue; Ma, Jie; Yang, Jingyu; Zhao, Longshan; Wu, Chunfu

    2016-09-01

    Xiao-Chai-Hu-Tang (XCHT) has been proven to be effective for the clinical treatment of depression. However, the mechanisms of definite antidepressant-like effects and detailed metabolic biomarkers were still unclear in this prior study. Here, we have investigated the metabolic profiles and potential biomarkers in a chronic unpredictable mild stress model after treatment with XCHT. Metabonomics based on ultra-high performance liquid chromatography coupled with mass spectrometry was used to profile the metabolic fingerprints of serum obtained from a rat model with chronic unpredictable mild stress with and without XCHT treatment. The model rats showed a significant decrease in sucrose preference and food consumption, and these depression-like symptoms were significantly improved by XCHT. Through principal component analysis (PCA), nine potential biomarkers of tryptophan, uric acid, phenylalanine, cholic acid and lysophosphatidylcholine (C18:0 LPC, C16:0 LPC, C16:1 LPC, C18:1 LPC, C20:4 LPC) were characterized as potential biomarkers involved the pathogenesis of depression. The therapeutic effect of XCHT on depression may involve in amino acid metabolism, lipid metabolism, oxidative stress and inflammation response. The present investigation highlights that metabonomics is a valuable tool for studying the essence of depression as well as evaluating the efficacy of the corresponding drug treatment. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. The simulation research of dissolved nitrogen and phosphorus non-point source pollution in Xiao-Jiang watershed of Three Gorges Reservoir area.

    Science.gov (United States)

    Wu, Lei; Long, Tian-Yu; Li, Chong-Ming

    2010-01-01

    Xiao-jiang, with a basin area of almost 5,276 km(2) and a length of 182.4 km, is located in the center of the Three Gorges Reservoir Area, and is the largest tributary of the central section in Three Gorges Reservoir Area, farmland accounts for a large proportion of Xiao-jiang watershed, and the hilly cropland of purple soil is much of the farmland of the watershed. After the second phase of water storage in the Three Gorges Reservoir, the majority of sub-rivers in the reservoir area experienced eutrophication phenomenon frequently, and non-point source (NPS) pollution has become an important source of pollution in Xiao-jiang Watershed. Because dissolved nitrogen and phosphorus non-point source pollution are related to surface runoff and interflow, using climatic, topographic and land cover data from the internet and research institutes, the Semi-Distributed Land-use Runoff Process (SLURP) hydrological model was introduced to simulate the complete hydrological cycle of the Xiao-jiang Watershed. Based on the SLURP distributed hydrological model, non-point source pollution annual output load models of land use and rural residents were respectively established. Therefore, using GIS technology, considering the losses of dissolved nitrogen and phosphorus in the course of transport, a dissolved non-point source pollution load dynamic model was established by the organic coupling of the SLURP hydrological model and land-use output model. Through the above dynamic model, the annual dissolved non-point source nitrogen and phosphorus pollution output as well as the load in different types were simulated and quantitatively estimated from 2001 to 2008, furthermore, the loads of Xiao-jiang Watershed were calculated and expressed by temporal and spatial distribution in the Three Gorges Reservoir Area. The simulation results show that: the temporal changes of dissolved nitrogen and phosphorus load in the watershed are close to the inter-annual changes of rainfall runoff, and the

  8. [Temperature modifies the acute effect of particulate air pollution on mortality in Jiang'an district of Wuhan].

    Science.gov (United States)

    Zhu, Y H; Wu, R; Zhong, P R; Zhu, C H; Ma, L

    2016-06-01

    To analyze the temperature modification effect on acute mortality due to particulate air pollution. Daily non-accidental mortality, cardiovascular mortality, and respiratory mortality data were obtained from Jiang'an District Center for Disease Control and Prevention. Daily meteorological data on mean temperature and relative humidity were collected from China Meteorological Data Sharing Service System. The daily concentration of particulate matter was collected from Wuhan Environmental Monitoring center. By using the stratified time-series models, we analyzed effects of particulate air pollution on mortality under different temperature zone from 2002 to 2010, meanwhile comparing the difference of age, gender and educational level, in Wuhan city of China. High temperature (daily average temperature > 33.4 ℃) obviously enhanced the effect of PM10 on mortality. With 10 μg/m(3) increase in PM10 concentrations, non-accidental, cardiovascular, and respiratory mortality increased 2.95% (95%CI: 1.68%-4.24%), 3.58% (95%CI: 1.72%-5.49%), and 5.07% (95%CI: 2.03%-9.51%) respectively. However, low temperature (daily average temperature respiratory mortality with 3.31% (95% CI: 0.07%-6.64%) increase. At high temperature, PM10 had significantly stronger effect on non-accidental mortality of female aged over 65 and people with high educational level groups. With an increase of 10 μg/m(3), daily non-accidental mortality increased 4.27% (95% CI:2.45%-6.12%), 3.38% (95% CI:1.93%-4.86%) and 3.47% (95% CI:1.79%-5.18%), respectively. Whereas people with low educational level were more susceptible to low temperature. A 10 μg/m(3) increase in PM10 was associated with 2.11% (95% CI: 0.20%-4.04%) for non-accidental mortality. Temperature factor can modify the association between the PM10 level and cause-specific mortality. Moreover, the differences were apparent after considering the age, gender and education groups.

  9. Influence of Jiang Tang Bu Shen Fang on expression of IKKβ mRNA in diabetic rats%降糖补肾方对糖尿病大鼠IKKβ mRNA表达的影响

    Institute of Scientific and Technical Information of China (English)

    范冠杰; 孙晓泽; 唐咸玉; 孙璐; 曾星; 罗广波; 卢绮韵; 温建炫

    2011-01-01

    目的 观察降糖补肾方对小剂量链脲佐菌素(STZ)加高脂饲料诱导的糖尿病模型大鼠肌肉组织IKK激酶β(IKKβ)信使核糖核酸(mRNA)表达的影响.方法 雄性SD大鼠高脂饲料喂养4周后注射小剂量STZ,1周后测大鼠空腹血糖,血糖值>11.1 mmoL/L者为造模成功的大鼠,将造模成功的大鼠随机分为模型组和降糖补肾方干预组,另设阿司匹林对照组和空白对照组,药物干预4周,取大腿肌肉组织,采用聚合酶链反应逆转录RT-PCR技术检测IKKβ mRNA表达水平.结果 模型组IKKβ mRNA表达明显高于空白对照组,是空白对照组的5.098倍(P0.05.结论 降糖补肾方在一定程度上能抑制糖尿病大鼠IKKβ mRNA基因,这可能是降糖补肾方抑制炎症信号通路的传导而发挥其改善胰岛素抵抗治疗糖尿病的机制之一.%Objective To observe the influence of Jiang Tang Bu Shen Fang on the expression of I kappa P kinase (IKKp) mRNA in muscular tissue in diabetic rats induced by low-dose streptozotocin ( STZ) and high-fat diet (HFD). Methods Male SD rats were fed HFD for 4 weeks, and then injected low-dose STZ. After one week the level of fasting plasma glucose was detected in rats and those with higher than 11. 1 mmol/L of level of fasting plasma glucose were successfully modeled. The rats were randomly divided into the model group, low-dose, mid-dose and high-dose Jiang Tang Bu Shen Fang groups (low-dose, mid-dose and high-dose groups), aspirin group and blank group. All groups were intervened by relevant medicinal for 4 weeks. The expression of IKKp mRNA in muscular tissue was detected by using reverse transcription polymerase chain reaction (RT-PCR). Results The expression of IKKp mRNA in the model group was significantly higher than that in the blank group (5.098 times, P 0. 05 compared with that in the model group. Conclusion Jiang Tang Bu Shen Fang can inhibit IKK(3 mRNA to some extent in diabetic rats, which may be one of mechanisms of the

  10. Genomewide identification, classification and analysis of NAC type ...

    Indian Academy of Sciences (India)

    Supplementary data: Genomewide identification, classification and analysis of NAC type gene family in maize. Xiaojian Peng, Yang Zhao, Xiaoming Li, Min Wu, Wenbo Chai, Lei Sheng, Yu Wang, Qing Dong,. Haiyang Jiang and Beijiu Cheng. J. Genet. 94, 377–390. Table 1. Detailed information of NAC proteins in maize.

  11. Studying the Formation and Development of Molecular Clouds: With the CCAT Heterodyne Array Instrument (CHAI)

    Science.gov (United States)

    Goldsmith, Paul F.

    2012-01-01

    Surveys of all different types provide basic data using different tracers. Molecular clouds have structure over a very wide range of scales. Thus, "high resolution" surveys and studies of selected nearby clouds add critical information. The combination of large-area and high resolution allows Increased spatial dynamic range, which in turn enables detection of new and perhaps critical morphology (e.g. filaments). Theoretical modeling has made major progress, and suggests that multiple forces are at work. Galactic-scale modeling also progressing - indicates that stellar feedback is required. Models must strive to reproduce observed cloud structure at all scales. Astrochemical observations are not unrelated to questions of cloud evolution and star formation but we are still learning how to use this capability.

  12. Color in packaging design : Case: ZheJiang JinSheng packaging Co,Ltd

    OpenAIRE

    Hu, Cuicui

    2010-01-01

    Color occupies an important position in packaging design, with the improvement of living standard, the higher requirement of color design in packaging. The aim of this thesis was to discuss key issues concerning aesthetics of packaging design. Topics will include an overview of the packaging design, the influence factor of packaging design, and introduce the aesthetics from packaging aspect. This thesis will also identify common problems of the production process, and list the phases of ho...

  13. Q. Shen1, X. Chen1, Jiyune Yi2, DR Jiang1 & YJ Yun3

    Indian Academy of Sciences (India)

    imately six months to cover the 2-yr pulsation cycle of VX Sgr. We used a special phase referencing ... but the υ = 2 line has relatively few maser features, most of which reside in the. Southern and Northern parts. ... stronger masers of both the lines appear, among which the main features reside in the inner shell and show ...

  14. Orbital Mechanics near a Rotating Asteroid Yu Jiang1,2,∗ & Hexi ...

    Indian Academy of Sciences (India)

    The Hamilton function can then be written as (Yu & Baoyin 2012a). H = 1. 2 .... The symplectic structure is a differential exterior 2-form defined on a ..... The disadvantage of Poisson-bracket, Poisson and cohomology forms is unavailable for ...

  15. Jiang et al., Afr J Tradit Complement Altern Med. (2015) 12(S):45-51 ...

    African Journals Online (AJOL)

    Background: To explore the effects of Zhi-Bai-Di-Huang-Wan (ZBDHW), a classic formula of Chinese medicinal herbs in relieving menopausal symptoms in British and Chinese women. Methods and Materials: Between May 2011 and May 2013, 224 Chinese and British women were divided into a ZBDHW group with 115.

  16. Analyzing the Discourse of Chais Conferences for the Study of Innovation and Learning Technologies via a Data-Driven Approach

    Science.gov (United States)

    Silber-Varod, Vered; Eshet-Alkalai, Yoram; Geri, Nitza

    2016-01-01

    The current rapid technological changes confront researchers of learning technologies with the challenge of evaluating them, predicting trends, and improving their adoption and diffusion. This study utilizes a data-driven discourse analysis approach, namely culturomics, to investigate changes over time in the research of learning technologies. The…

  17. Comment on "Fault Tolerant analysis for stochastic systems using switching diffusion processes' by Yang, Jiang and Cocquempot

    DEFF Research Database (Denmark)

    Schiøler, Henrik; Leth, John-Josef

    2011-01-01

    Results are given in [Yang et. al. 2009] regarding the overall stability of switched diffusion processes based on stability properties of separate processes combined through stochastic switching. This paper argues two main results to be empty, in that the presented hypotheses are logically...

  18. Some Cherished Memories of My Old Friend Jiang Dingxian%缅怀老友江定仙

    Institute of Scientific and Technical Information of China (English)

    廖辅叔

    2001-01-01

    最近一些年来,老朋友一个又一个的走了,现在结识最早的老友中间的一位——江定仙又离开了我们。我写挽联的时候,不得不凄然长叹:“桑榆寻故旧,可怜在世已无多!”

  19. Therapeutic Effects of Saireito (Chai-Ling-Tang, a Traditional Japanese Herbal Medicine, on Lymphedema Caused by Radiotherapy: A Case Series Study

    Directory of Open Access Journals (Sweden)

    Aiko Nagai

    2013-01-01

    Full Text Available Despite the development of radiotherapy machines and technologies, a proportion of patients suffer from radiation-induced lymphedema. Saireito (SRT is a traditional Japanese herbal medicine that has been used for treating edema and inflammation in conditions such as nephritic disease. This study investigated the effect of SRT on lymphedema caused by radiotherapy. Four patients were treated with SRT at a dose of 9 g/day. The severity of lymphedema was evaluated using the Common Terminology Criteria for Adverse Events version 4 and Numerical Rating Scale before and after SRT treatment. After the treatment with SRT, 2 of 4 patients (50% showed apparent improvement in lymphedema. One of the cases had difficulty in wearing the custom-made thermoplastic cast, but after SRT administration, he could wear the mask easily. One case decided to stop taking SRT 3 days after initiation because cough and fever appeared. In conclusion, it is important to control the side effects of radiotherapy, which leads to improved tumor control rates. Prospective randomized studies are necessary to confirm the findings of this case series study.

  20. Chaîne de services efficaces en énergie grâce à la virtualisation des fonctions réseaux

    OpenAIRE

    Tomassilli , Andrea; Huin , Nicolas; Giroire , Frédéric; Jaumard , Brigitte

    2016-01-01

    Service Function Chains (SFCs) are an ordered sequence of network functions, such as firewall. Using the new approaches of Software Defined Networks and of Network Function Virtualization (NFV), the network functions can be virtualized and executed on generic hardware. To optimize network management, it is thus crucial to place dynamically the network functions at the right positions in the network according to the network traffic. In this paper, we consider the problem of SFC placement with ...

  1. Some Memories of my Old Friend Jiang Ding-xian and his Works%回忆往事赏读作品--怀念定仙老友

    Institute of Scientific and Technical Information of China (English)

    缪天瑞

    2002-01-01

    @@ 中央音乐学院为纪念江定仙教授诞辰90周年暨逝世两周年,将于今年10月举行学术性纪念活动,约我为定仙撰文.我搜索远去的记忆,并再次赏读他的作品,又参考有关资料缀成此文,以抒友情,以志缅怀.

  2. Violence Against Women: Injuries and Deaths in Rhode Island Yongwen Jiang, PhD; Deborah Debare, MMHS; Lynne-Marie Shea, BA; Samara Viner-Brown, MS.

    Science.gov (United States)

    Jiang, Yongwen; DeBare, Deborah; Shea, Lynne-Marie; Viner-Brown, Samara

    2017-12-01

    Violence against women is a public health issue. Monitoring assault-related injury and homicide death among women is imperative for understanding this public health issue. We used data from the 2014 Rhode Island emergency department (ED), hospital discharge (HD), and 2004-2014 Rhode Island violent death reporting system (RIVDRS) to provide a broad picture for violence against women injuries and deaths in Rhode Island. ED visit and HD data show that the majority of female assault injuries occurred among women aged 25-44, resided in the core cities, and had public insurance. RIVDRS data showed that over half of the homicides among women were aged 25-64; nearly two in five were non-Hispanic black or Hispanic. Precipitating circumstances include intimate partner violence, a preceding argument or a conflict, and precipitated by another crime. Evidence-informed interventions need to target high-risk populations and urban areas to effectively reduce violence against women. [Full article available at http://rimed.org/rimedicaljournal-2017-12.asp].

  3. Jiang Tang Xiao Ke Granule Play an Anti-diabetic Role in Diabetic Mice Pancreatic Tissue by Regulating the mRNAs and MicroRNAs Associated with PI3K-Akt Signaling Pathway

    Directory of Open Access Journals (Sweden)

    Fang-Fang Mo

    2017-11-01

    Full Text Available Purpose: To investigate the effect of JTXK granule on the expression pattern of miRNA in pancreatic tissue of KKAy diabetic mice, and to explore the molecular mechanism and pathways of JTXK granule in anti-diabetic effect.Methods: We used high fat diet (HFD to induce the KKAy diabetic mice and screened the differentially expressed miRNAs (DEMs between JTXK-treated group (n = 6 and the diabetic group (n = 6 using MicroRNA (miRNA Microarray. C57BL/6J mice were given a normal diet as the control group (n = 6. Subsequently, miRNA target gene prediction, GO and Pathway analysis were used to explore the function of DEMs. Finally, the mechanism of anti-diabetic effects of JTXK granule was tested by in vitro INS-1 pancreatic β-cell experiment.Results: The blood glucose and body weight of JTXK-treated group was significantly lower compared with the model group. Moreover, a total of 45 miRNAs with significant differences were detected in the model group and the JTXK-treated group (P ≤ 0.05, Fold Change > 2. Further, miRNA-mRNA analysis showed that the differential expression of mmu-miR-192-5p, mmu-miR-291a-3p, mmu-miR-320-3p, mmu-miR-139-5p and mmu-miR-378a-3p are closely related to pancreatic histological changes. In addition, pathway analysis showed that the DEMs were closely related to PI3K-Akt Signaling Pathway. Furthermore, the levels of serine/threonine-protein kinase (Akt, phosphorylated Akt (p-Akt and phosphorylated forkhead transcription factor O1 (p-Foxo1 in INS-1-FOXO1 overexpressing model cells were lower than those in normal group, while JTXK granules could increase the expression of Akt, p-Akt and p-Foxo1.Conclusions: The results showed that JTXK granule could play an anti-diabetic role by regulating the mRNA and miRNAs associated with PI3K-Akt pathway in diabetic mice pancreatic tissue.

  4. Comment on "Electron impact excitation of N-like ions from the ICFT R-matrix calculation" by HB Wang, G Jiang, XF Li, and ZC He in At. Data Nucl. Data Tables 120 (2018) 373-429

    Science.gov (United States)

    Aggarwal, Kanti M.

    2018-03-01

    The paper "Electron impact excitation of N-like ions from the ICFT R-matrix calculation" by Wang et al. [1] lacks details of calculations, presents only limited data, and has a few anomalies, as listed below.

  5. Triazole derivatives with improved in vitro antifungal activity over azole drugs

    Directory of Open Access Journals (Sweden)

    Yu S

    2014-04-01

    Full Text Available Shichong Yu,1,* Xiaoyun Chai,1,* Yanwei Wang,1 Yongbing Cao,2 Jun Zhang,3 Qiuye Wu,1 Dazhi Zhang,1 Yuanying Jiang,2 Tianhua Yan,4 Qingyan Sun11Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China; 2Drug Research Center, School of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China; 3Overseas Education Faculty of the Second Military Medical University, Shanghai, People's Republic of China; 4Department of Pharmacology, School of Pharmacy, China Pharmaceutical University, Nanjing, People's Republic of China*These authors contributed equally to this workAbstract: A series of triazole antifungal agents with piperidine side chains was designed and synthesized. The results of antifungal tests against eight human pathogenic fungi in vitro showed that all the compounds exhibited moderate-to-excellent activities. Molecular docking between 8d and the active site of Candida albicans CYP51 was provided based on the computational docking results. The triazole interacts with the iron of the heme group. The difluorophenyl group is located in the S3 subsite and its fluorine atom (2-F can form H-bonds with Gly307. The side chain is oriented into the S4 subsite and formed hydrophobic and van der Waals interactions with the amino residues. Moreover, the phenyl group in the side chain interacts with the phenol group of Phe380 through the formation of π–π face-to-edge interactions.Keywords: synthesis, CYP51, molecular docking, azole agents

  6. Pediatric Palliative Care: A Personal Story

    Medline Plus

    Full Text Available ... Stars 13,478 views 10:35 Samara, Childhood Cancer Warrior - Chai Lifeline - Duration: 4:28. Chai Lifeline ... views 4:28 The Ugly Truth of Pediatric Cancer - Duration: 5:21. KidsCancerChannel 64,459 views 5: ...

  7. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. Chen Chai. Articles written in Journal of Chemical Sciences. Volume 126 Issue 3 May 2014 pp 813-820 Regular Articles. First total synthesis of Boehmenan · Yamu Xia Xiaoli Dai Haixin Liu Chen Chai · More Details Abstract Fulltext PDF. The first total synthesis of dilignan ...

  8. 基于游客感知的江南园林旅游容量探讨--以扬州个园为例%A Discussion of Tourism Carrying Capacity of JiangNan Gardens---Take Yangzhou Ge Garden for Instance

    Institute of Scientific and Technical Information of China (English)

    王彦龙

    2014-01-01

    通过访谈调研和问卷调查两种形式,对近年来扬州个园景区的基于游客感知的旅游容量的具体情况进行了实际评估和探讨研究,得出一些关于个园旅游容量的实际问题,找出影响个园旅游容量的一些主客观因素,并有针对性地提出可行性措施和建议。%This paper highlights the practical evaluation and argumentative survey of the specific condition , which based on the tourists ’ perceptional capacity of tourism through the interview survey and questionnaire survey for Yangzhou Ge Garden in recent years .Moreover , the survey gets some conclusions about the practical question of capacity of tourism .In the meanwhile , this paper also found out some subjective factors which can affect the capac-ity of the tourism and suggests some practical measures and suggestion to the specific aspects .

  9. Study on Restriction Contract in Huizhou during Qing Dynasty-48 Pieces of Restriction Contract in Huizhou of Yu Jiang's Collection%论清代徽州禁约合同--以俞藏48件徽州禁约文书为中心

    Institute of Scientific and Technical Information of China (English)

    陈云朝; 童旭

    2014-01-01

    Restriction contract is a kind of contract documents in which the clansmen and fellow villagers covenant and negotiate penalty provisions to prohibit stealing and chopping trees,protecting Lailong, Shuikou and other affairs.It has a broad application scope and diverse types;meanwhile the main contrac-ting body is generally a clan,an association or a union of people with different surnames.The contents trend to embody compulsory regulations on prohibition and punishment.The validity of restriction contract is guaranteed by self protection or “submitting to the government for treatment.”As the necessary comple-ment and extension of the national law,it plays an important role in the construction of the basic social or-ders.%禁约合同是同族、同村人等为禁止盗窃、砍伐树木、保护来龙与水口等事务,共同立约承诺并议定罚则的合同文书。其适用领域广泛,类型多样,订立主体多为宗族、会社以及数姓的联合;内容上更多地体现为禁止、惩罚等强制性规范。对违禁行为进行私力救济或“呈官究治”,保证了禁约合同效力的实施。作为国家法的必要补充和延伸,禁约合同在基层社会秩序的构建中扮演了十分重要的角色。

  10. Perceived usefulness and culture as predictors of teachers attitudes ...

    African Journals Online (AJOL)

    Sumaya Laher

    2015-11-24

    Nov 24, 2015 ... encourages creativity and promotes higher-order learning (Chai, Hong & Teo ... Teacher attitudes towards educational technology in. South Africa. Govender ..... As is evident from the demographic profile and scores on the ET ...

  11. Kinetic investigation on enantioselective hydrolytic resolution of ...

    African Journals Online (AJOL)

    Kinetic investigation on enantioselective hydrolytic resolution of epichlorohydrin by crude epoxide hydrolase from domestic duck liver. X Ling, D Lu, J Wang, J Chen, L Ding, J Chen, H Chai, P Ouyang ...

  12. Main: 1WEO [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available tic Subunit Name=Irx3; Synonyms=T10b6_80; Arabidopsis Thaliana Molecule: Cellulose Synthase, Catalytic Subunit (Irx3); Chai...GDKEHLMSEMNFEKTFGQSSIFVTSTLMEEGGVPPSSSPAVLLKEAIHVISCGYEDKTEWGTELGWIYGSITEDILTGFKMHCRGWRSIYCMPKRPAFKGSAPINLSD...RLNQVLRWALGSVEIFFSRHSPLWYGYKGGKLKWLERFAYANTTIYPFTSIPLLAYCILPAICLLTDKFIMPPISTFASLFFISLFMSIIVTGILELRWSGVSIEEWW...RNEQFWVIGGISAHLFAVVQGLLKILAGIDTNFTVTSKATDDDDFGELYAFKWTTLLIPPTTVLIINIVGVVAGISDAINNGYQSWGPLFGKLFFSFWVIVHLYPFLKGLMGRQNRTPTIVVIWSVLLASIFSLLWVRIDPFVLKTKGPDTSKCGINC arabi_1WEO.jpg ...

  13. Main: 1W0I [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available Synonym: 3-Ketoacyl-Acyl Carrier Protein Synthase, Mitochondrial Beta-Ketoacyl-Acyl Carrier Protein Synthase; Chai...VIVLEEYEHAKRRGAKIYAELCGYGMSGDAHHITQPPEDGKGAVLAMTRALRQSGLCPNQIDYVNAHATSTPIGDAVEARAI...KTVFSEHATSGTLAFSSTKGATGHLLGAAGAVEAIFSILAIHHGVAPMTLNVKNPDPIFDKRFMPLTTSKKMLVRTAMSNSFGFGGTNASLLFASI arabi_1W0I.jpg ...

  14. Disease: H00420 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available enstein RB, Pollin TI, Sreenivasan UT, Chai S, Blaner WS, Snitker S, O'Connell JR...740-8 (2011) DOI:10.1056/NEJMoa1007487 ... PMID:24848981 (gene) ... AUTHORS ... Albert JS, Yerges-Armstrong LM, Hor

  15. Reference: 418 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 418 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u16856986i Chai Mao-Feng...cid responses in Arabidopsis. 5 665-74 16856986 2006 Sep The Plant journal An Rui|Chai Mao-Feng|Chen Jia|Chen Qi-Jun|Wang Xue-Chen|Wei Peng-Cheng|Yang Shuhua

  16. Reference: 291 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 291 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u16244906i Chai Mao-Feng...d chloroplast protection. 4 553-64 16244906 2005 Nov Plant molecular biology An Rui|Chai Mao-Feng|Chen Jia|Chen Qi-Jun|Chen Ye-Miao|Wang Xue-Chen

  17. Development and Validation of the Consumer Health Activation Index.

    Science.gov (United States)

    Wolf, Michael S; Smith, Samuel G; Pandit, Anjali U; Condon, David M; Curtis, Laura M; Griffith, James; O'Conor, Rachel; Rush, Steven; Bailey, Stacy C; Kaplan, Gordon; Haufle, Vincent; Martin, David

    2018-04-01

    Although there has been increasing interest in patient engagement, few measures are publicly available and suitable for patients with limited health literacy. We sought to develop a Consumer Health Activation Index (CHAI) for use among diverse patients. Expert opinion, a systematic literature review, focus groups, and cognitive interviews with patients were used to create and revise a potential set of items. Psychometric testing guided by item response theory was then conducted among 301 English-speaking, community-dwelling adults. This included differential item functioning analyses to evaluate item performance across participant health literacy levels. To determine construct validity, CHAI scores were compared to scales measuring similar personality constructs. Associations between the CHAI and physical and mental health established predictive validity. A second study among 9,478 adults was used to confirm CHAI associations with health outcomes. Exploratory factor analyses revealed a single-factor solution with a 10-item scale. The CHAI showed good internal consistency (alpha = 0.81) and moderate test-retest reliability (ICC = 0.53). Reading grade level was found to be at the 6 th grade. Moderate to strong correlations were found with similar constructs (Multidimensional Health Locus of Control, r = 0.38, P measures (depression, r = -0.28, P < 0.001; anxiety, r = -0.22, P < 0.001; and physical functioning, r = 0.22, P < 0.001). In the validation sample, the CHAI was significantly associated with self-reported physical and mental health ( r = 0.31 and 0.32 respectively; both P < 0.001). The CHAI appears to be a valid, reliable, and easily administered tool that can be used to assess health activation among adults, including those with limited health literacy. Future studies should test the tool in actual use and explore further applications.

  18. Commentary on "Optimal schedule of bacillus Calmette-Guérin for non-muscle-invasive bladder cancer: A meta-analysis of comparative studies." Zhu S, Tang Y, Li K, Shang Z, Jiang N, Nian X, Sun L, Niu Y, Department of Urology Tianjin Institute of Urology, 2nd Hospital of Tianjin Medical University, People's Republic of China.: BMC Cancer 2013; 13:332. doi:10.1186/1471-2407-13-332.

    Science.gov (United States)

    See, William A

    2014-11-01

    To explore the necessity of maintenance, efficacy of low-dose and superiority of various combination therapies of Bacillus Calmette-Guérin (BCG) in treatment of superficial bladder cancer (BCa). Comprehensive searches of electronic databases (PubMed, Embase, and the Cochrane Library), were performed, then a systematic review and cumulative meta-analysis of 21 randomized, controlled trials (RCTs) and 9 retrospective comparative studies were carried out according to, predefined inclusion criteria. Significantly better recurrence-free survivals (RFS) were observed respectively in patients who received BCG maintenance, standard-dose and BCG plus epirubicin therapy comparing to those received induction, low-dose and BCG alone. BCG maintenance therapy was also associated with significantly better progression-free survival (PFS), but there were more incidences of adverse events. Pooled results showed no remarkable advantage of BCG combined with Mitomycin C or with interferon α-2b in improving oncologic outcomes. Sensitivity-analyses stratified by study-design and tumor stage led to very similar overall results and often to a decrease of the between-study heterogeneity. Our data confirmed that non-RCT only affected strength rather than direction of the overall results. All patients with superficial BCa should be encouraged to accept BCG maintenance therapy with standard-dose if well tolerated. Patients can benefit from BCG combined with epirubicin but not from BCG combined with Mitomycin C or interferon α-2b. Copyright © 2014 Elsevier Inc. All rights reserved.

  19. Web-Based Just-in-Time Information and Feedback on Antibiotic Use for Village Doctors in Rural Anhui, China: Randomized Controlled Trial.

    Science.gov (United States)

    Shen, XingRong; Lu, Manman; Feng, Rui; Cheng, Jing; Chai, Jing; Xie, Maomao; Dong, Xuemeng; Jiang, Tao; Wang, Debin

    2018-02-14

    /532) and 23.5% (125/352), respectively, at baseline and 80.8% (417/532) and 19.2% (99/532) at endpoint. JITIF resulted in substantial improvement in delivery of essential service procedures (2.6%-24.8% at baseline on both arms and at endpoint on the control arm vs 88.5%-95.0% at endpoint on the intervention arm, P<.001), beliefs favoring rational antibiotics use (11.5%-39.8% at baseline on both arms and at endpoint on the control arm vs 19.8%-62.6% at endpoint on the intervention arm, P<.001) and knowledge about side effects of antibiotics (35.7% on the control arm vs 73.7% on the intervention arm, P<.001), measures for managing or preventing RTIs (39.1% vs 66.7%, P=.02), and measures for managing or preventing GTIs (46.8% vs 69.2%, P<.001). It also reduced antibiotics prescription (from 88.8%-62.3%, P<.001), and this decrease was consistent for RTIs (87.1% vs 64.3%, P<.001) and GTIs (94.7% vs 52.4%, P<.001). JITIF is effective in controlling antibiotics prescription at least in the short term and may provide a low-cost and sustainable solution to the widespread excessive use of antibiotics in rural China. ©XingRong Shen, Manman Lu, Rui Feng, Jing Cheng, Jing Chai, Maomao Xie, Xuemeng Dong, Tao Jiang, Debin Wang. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 14.02.2018.

  20. Random Coefficient Logit Model for Large Datasets

    NARCIS (Netherlands)

    C. Hernández-Mireles (Carlos); D. Fok (Dennis)

    2010-01-01

    textabstractWe present an approach for analyzing market shares and products price elasticities based on large datasets containing aggregate sales data for many products, several markets and for relatively long time periods. We consider the recently proposed Bayesian approach of Jiang et al [Jiang,

  1. Effect of temperature on structure and corrosion resistance for ...

    Indian Academy of Sciences (India)

    The effect of plating temperatures between 60 and 90◦C on structure and corrosion resistance for elec- troless NiWP coatings ..... which helps to form fine grain. At 80 .... [23] Zhang W X, Jiang Z H, Li G Y and Jiang Q 2008 Surf. Coat. Technol.

  2. An anti-ferromagnetic terephthalate-bridged trigonal prismatic ...

    Indian Academy of Sciences (India)

    M. Scheme 1. Possible coordination modes of terephthalate. (tp). 2. ..... W and Atwood J L 2009 In Supramolecular Chemistry .... (a) Jiang Z Q, Zhao Z, Jiang G Y, Hou D C, Kang Y ... (a) Li H, Eddaoudi M, O'Keeffe M and Yaghi O M 1999.

  3. Spectroscopic classification of PTSS-18ecg (SN 2018bhb) as a type Ia supernova around maximum

    Science.gov (United States)

    Zhang, Jujia; Ding, Xu; Wang, Xiaofeng; Li, Wenxiong; Li, Bin; Xu, Zhijian; Tan, Hanjie; Zhao, Haibin; Wang, Lifan; Li, Zhitong

    2018-05-01

    We obtained an optical spectrum (range 350-890 nm) of PTSS-18ecg (SN 2018bhb), discovered by the PMO-Tsinghua Supernova Survey (PTSS, http://www.cneost.org/ptss/), on UT 2018 May 10.7 with the Li-Jiang 2.4 m telescope (LJT+YFOSC) at Li-Jiang Observatory of Yunnan Observatories.

  4. Investigations of Tissue-Level Mechanisms of Primary Blast Injury Through Modeling, Simulation, Neuroimaging and Neuropathological Studies

    Science.gov (United States)

    2012-07-10

    2007;25(1):97-98. [19] Stewart C. Blast Injuries. Colorado Springs: USAF Academy Hospital; 2006. 88 p. [20] Cernak I, Wang Z, Jiang J, Bian X, Savic J...Wang Z, Jiang J, Bian X, Savic J. Ultrastructural and Functional Characteristics of Blast Injury- Induced Neurotrauma. Journal of Trauma: Injury

  5. Biological and Clinical Characterization of Novel lncRNAs Associated with Metastatic Prostate Cancer

    Science.gov (United States)

    2014-10-01

    Matthew K. Iyer, Yang Shi, Xia Jiang, June Escara-Wilke, Rachell Brendenis, Dmitry Borkin, Anastasia K. Yocum, Dattatreya Mellacheruvu, Yuanyuan... Anastasia Yocum, Anton Poliakov, Vishal Kothari, Xiaojun Jing, Harika Gundlapalli, Xuhong Cao, Xiaoju Wang, Rohit Malik, PhD...Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry

  6. Main: 1DU5 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1DU5 トウモロコシ Corn Zea mays L. Zeamatin Precursor. Name=Zlp; Zea Mays Molecule: Zeamatin; Chai...eta Sandwich SWS:ZEAM_MAIZE,P33679|EMBL; U06831; AAA92882.1; -.|PIR; T02075; T02075.|PDB; 1DU5; X-ray; A/B=22-227.|Mai

  7. Expression of ET(A) and ET(B) receptor mRNA in human cerebral arteries

    DEFF Research Database (Denmark)

    Hansen-Schwartz, J; Szok, D; Edvinsson, L

    2002-01-01

    The vascular effects of endothelins (ET) are in mammals mediated via two receptor subtypes, endothelin A (ET(A), mainly constrictive) and endothelin B (ET(B), mainly dilating) receptors. We have examined the presence of ET(A) and ET(B) receptor mRNA using the reverse transcription polymerase chai...

  8. Cloning and characterization of peptidylprolyl isomerase B in the ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-12-15

    Dec 15, 2009 ... 1Institute of Life Sciences, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, P. R. China. 2Beijing ... 6 Tianshuiyuan Street, Chaoyang District, Beijing 100026, P. R. China. ... Kang et al., 2008). Cyclophilins were ..... Xu YX, Manley JL (2007). ... Yao Q, Li M, Yang H, Chai H, Fisher W, Chen C (2005).

  9. A Preliminary Study of College Room-Bound Male Students: Concept Exploration and Instrument Development

    Science.gov (United States)

    Chou, Chien; Wu, Huan-Chueh; Wang, Mei-Hung

    2011-01-01

    From time to time, cases of over-dependence on the Internet have been observed on college campuses. Some students, especially male students, remain connected to the Internet as long as they are awake. In Chinese, the emerging term (chai-nan) is used to describe this kind of young man, meaning "room-bound male," who seldom leaves his…

  10. Giant mediastinal schwannoma located in the lower right side of the ...

    African Journals Online (AJOL)

    2016-01-18

    Jan 18, 2016 ... nerve. The tumor was coated with a white envelope and filled. Giant mediastinal schwannoma located in the lower right side of the chest. Y Wu, J Zhang, Y Chai. Department of Thoracic Surgery, School of Medicine, Second Affiliated Hospital, Zhejiang University, Hangzhou, China. Access this article online.

  11. Managing Endometriosis in sub-Saharan Africa: Emerging Concepts ...

    African Journals Online (AJOL)

    AJRH Managing Editor

    . Obstet 1987; 25: 47 – 52. 8. Kyama CM, Mwenda JM, Machoki J, Mihalyi A,. Simsa P, Chai DC, D'Hoodge TM. Endometriosis in African women. Women's. Health 2007; 3(5): 629 – 635. 9. D' Hoodge TM. The challenge of Endometriosis: A.

  12. Journal of Astrophysics and Astronomy | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... Our results suggest that black holes in radio galaxies are rapidly spinning. Volume 35 Issue 3 September 2014 pp 357-362 Part IV: Emission Models and Theory. What Governs Lorentz Factors of Jet Components in Blazars? Xinwu Cao Bo Chai Ming Zhou Minfeng Gu · More Details Abstract Fulltext PDF.

  13. Global supply chain management/transportation : building a global network of scholars and educators : phase I

    Science.gov (United States)

    2008-01-01

    During the project period two conferences--1st Symposium and Workshop in Global : Supply Chain (http://www.business.utoledo.edu/scm) at University of Toledo, Toledo, : OH, USA (October 6-7, 2007) and 2nd Symposium and Workshop in Global Supply : Chai...

  14. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. ZHONG DU1 BO TIAN1 XI-YANG XIE1 JUN CHAI1 XIAO-YU WU1. State Key Laboratory of Information Photonics and Optical Communications, and School of Science, Beijing University of Posts and Telecommunications, Beijing 100876, China ...

  15. Epp Petrone lemmikreisiraamatud / Epp Petrone

    Index Scriptorium Estoniae

    Petrone, Epp, 1974-

    2013-01-01

    Tutvustus: Bryson, Bill. Ei siin ega seal : reisid Euroopas. [Tallinn] : Tänapäev, c2011 ; Grzimek, Bernhard. Serengeti ei tohi surra. Tallinn : Eesti Raamat, 1978 ; Kaun, Eeva. Minu India : mister Singhi surm ja tuhat tassi chai'd. [Tartu] : Petrone Print, c2012

  16. Molecular Typing and Differentiation

    Science.gov (United States)

    In this chapter, general background and bench protocols are provided for a number of molecular typing techniques in common use today. Methods for the molecular typing and differentiation of microorganisms began to be widely adopted following the development of the polymerase chai...

  17. Dicty_cDB: Contig-U11847-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 00512_699( AE000512 |pid:none) Thermotoga maritima MSB8, comple... 42 0.065 JC2551( JC2551 ) tropomyosin alpha chain - axolotl...AltName: Full=Myosin heavy chai... 42 0.11 JC6199( JC6199 ) alpha-tropomyosin S-1 - axolotl &U33450_1(U33450

  18. Data of evolutionary structure change: 2QU0A-2DXMB [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available n>A 2QU0A WGKVGGNAGAYGence> HHH...2QU0A-2DXMB 2QU0 2DXM A B -VLSAADKSNVKAAWGKVGGNAGAYGAEALERMFLSFPT...ID> 0 2DXM B 2DXMB ...ence>WGKVN--VDEVGence> GGG --HHHHH VAL CA 716 GLY CA 753 2QU0 Chai

  19. Integrating Linear Programming and Analytical Hierarchical ...

    African Journals Online (AJOL)

    Study area is about 28000 ha of Keleibar- Chai Watershed, located in eastern Azerbaijan, Iran. Socio-economic information collected through a two-stage survey of 19 villages, including 300 samples. Thematic maps also have summarized Ecological factors, including physical and economic data. A comprehensive Linear ...

  20. Main: 1V3H [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1V3H 大豆 Soybean Glycine max (L.) Merrill Beta-Amylase Name=Bmy1; Glycine Max Molecule: Beta-Amylase; Chai... 495 AA, Molecular weight: 56011 Da ATSDSNMLLNYVPVYVMLPLGVVNVDNVFEDPDGLKEQLLQLRAAGVDGVMVDVWWGIIELKGPKQYDWRAYRSLFQLVQECGLTLQAI...MSFHQCGGNVGDIVNIPIPQWVLDIGESNHDIFYTNRSGTRNKEYLTVGVDNEPIFHGRTAIEIYSDYMKSFRENMSDFLESGLIIDIEVG...FLTWYSNKLLNHGDQILDEANKAFLGCKVKLAIKVSGIHWWYKVENHAAELTAGYYNLNDRDGYRPIARMLSRHHAILNFTCLEMRDSEQPSDAKSGPQELVQQVLSG...GWREDIRVAGENALPRYDATAYNQIILNAKPQGVNNNGPPKLSMFGVTYLRLSDDLLQKSNFNIFKKFVLKMHADQDYCANPQKYNHAITPLKPSAPKIPIEVLLEATKPTLPFPWLPETDMKVDG soybean_1V3H.jpg ...

  1. 78 FR 40516 - Sunshine Act Meetings

    Science.gov (United States)

    2013-07-05

    ... hear from a panel of policy experts on new models of workplace accommodations, including Chai Feldblum, Commissioner, Equal Employment Opportunity Commission; John Evans, WA Vocational Rehabilitation Employer..., NCD will receive public comment from individuals interested in focusing their remarks on workplace...

  2. Multiple Cationic Amphiphiles Induce a Niemann-Pick C Phenotype and Inhibit Ebola Virus Entry and Infection

    Science.gov (United States)

    2013-02-18

    Volume 8 | Issue 2 | e56265 mL. After disrupting the membranes with 20 mM methionine methyl -ester for 1 hr at RT, ,150 mg of disrupted NPC1- enriched...PLoS Biol 9: e1000598. 42. Simmons G, Rennekamp AJ, Chai N, Vandenberghe LH, Riley JL, et al. (2003) Folate receptor alpha and caveolae are not required

  3. Hansen Solubility Parameters for Octahedral Oligomeric Silsesquioxanes

    Science.gov (United States)

    2012-08-28

    1997, 80, 386-&. 5. Hansen, C. M. The three-dimensional solubility parameter -- key to paint component affinities I. J. Paint Technol. 1967, 39, 104...Chai, J.; Zhang, Q. X.; Han, D. X.; Niu, L. Synthesis and Application of Widely Soluble Graphene Sheets. Langmuir 2010, 26, 12314-12320. 12. Hansen, C

  4. Global strategies to reduce the price of antiretroviral medicines: evidence from transactional databases.

    Science.gov (United States)

    Waning, Brenda; Kaplan, Warren; King, Alexis C; Lawrence, Danielle A; Leufkens, Hubert G; Fox, Matthew P

    2009-07-01

    To estimate the impact of global strategies, such as pooled procurement arrangements, third-party price negotiation and differential pricing, on reducing the price of antiretrovirals (ARVs), which currently hinders universal access to HIV/AIDS treatment. We estimated the impact of global strategies to reduce ARV prices using data on 7253 procurement transactions (July 2002-October 2007) from databases hosted by WHO and the Global Fund to Fight AIDS, Tuberculosis and Malaria. For 19 of 24 ARV dosage forms, we detected no association between price and volume purchased. For the other five ARVs, high-volume purchases were 4-21% less expensive than medium- or low-volume purchases. Nine of 13 generic ARVs were priced 6-36% lower when purchased under the Clinton Foundation HIV/AIDS Initiative (CHAI). Fifteen of 18 branded ARVs were priced 23-498% higher for differentially priced purchases compared with non-CHAI generic purchases. However, two branded, differentially priced ARVs were priced 63% and 73% lower, respectively, than generic non-CHAI equivalents. Large purchase volumes did not necessarily result in lower ARV prices. Although current plans for pooled procurement will further increase purchase volumes, savings are uncertain and should be balanced against programmatic costs. Third-party negotiation by CHAI resulted in lower generic ARV prices. Generics were less expensive than differentially priced branded ARVs, except where little generic competition exists. Alternative strategies for reducing ARV prices, such as streamlining financial management systems, improving demand forecasting and removing barriers to generics, should be explored.

  5. Scientific and Popular Health Knowledge in the Education Work of Community Health Agents in Rio de Janeiro Shantytowns

    Science.gov (United States)

    Zanchetta, M. S.; Kolawole Salami, B.; Perreault, M.; Leite, L. C.

    2012-01-01

    Health education for socially marginalized populations challenges the efficacy of existing strategies and methods, and the pertinence of the educational and philosophical principles that underpin them. The Brazilian Community Health Agents Initiative (CHAI) hires residents of deprived marginalized communities to undertake health promotion and…

  6. Pharmacological Experimental Study Of The Anti-Depressant Effect ...

    African Journals Online (AJOL)

    Pharmacological Experimental Study Of The Anti-Depressant Effect Of Total Saikosaponins. Y Liu, C Cao, H Ding. Abstract. Background: Chai Hu has the hepato-protective, choleretic, anti-tussive, analgesic, anti-inflammatory, anti-viral, hypotensive, hypolipidemic, and anti-tumor pharmacological effects. In this study, the ...

  7. Erratum: Quantum corrections and black hole spectroscopy

    Science.gov (United States)

    Jiang, Qing-Quan; Han, Yan; Cai, Xu

    2012-06-01

    In my paper [Qing-Quan Jiang, Yan Han, Xu Cai, Quantum corrections and black hole spectroscopy, JHEP 08 (2010) 049], there was an error in deriving the black hole spectroscopy. In this erratum, we attempt to rectify them.

  8. Effects of over-expression of allene oxide cyclase on camptothecin ...

    African Journals Online (AJOL)

    emily

    2012-03-22

    Mar 22, 2012 ... biosynthetic pathway genes and higher yields of nicotine. (Jiang et al., 2009). ... EXPERIMENTALS. Construction of CaAOC expression vector ... and rinsed thoroughly five times in sterile distilled water. Then, the wounded ...

  9. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Lihua Jiang1 Aiyi Zhu1 Jianse Zhang1 Changwen Wu1. National Engineering Research Center of Marine Facilities Aquaculture, College of Marine Science, Zhejiang Ocean University, Zhoushan 316022, China ...

  10. The effect of drought stress and exogenous abscisic acid on growth ...

    African Journals Online (AJOL)

    Jane

    2011-08-17

    Aug 17, 2011 ... and Zhang, 2001). .... and APX (Jiang and Zhang 2002). According to Keleo .... improve drought tolerance of fine grain aromatic rice (Oryza sativa. L.). ... Structure and differential response to abscisic acid of two promoters.

  11. to view fulltext PDF

    Indian Academy of Sciences (India)

    Madhu

    analysis of yeast and Arabidopsis indicates that these species do not have lamins .... accompanied by insulin-resistant diabetes, hyperlipidemia, and atherosclerotic ..... V, Mohr A, Meta M, Genant H, Jiang Y et al 2002 Zmpste24 deficiency in ...

  12. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Fang Dong1 Jiang Chenning1 Zhu Ting1 Yang Jinming1. Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering, Yancheng Teachers University, 50 Kai Fang Da Dao, Yancheng 224002, Jiangsu, P. R. China ...

  13. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Juan Li1 Ruisong Guo1 Hong Jiang2. Key Laboratory of Advanced Ceramics and Machining Technology, Ministry of Education, Tianjin University, Tianjin 300072, China; Guizhou Broadcasting and Television College, Guiyang 550004, China ...

  14. Mechanical behaviour of nanoparticles: Elasticity and plastic ...

    Indian Academy of Sciences (India)

    2015-06-03

    Jun 3, 2015 ... Introduction. In the framework of material sciences, a nano-object refers to any structure whose ... improve the quality of nanomanufacturing processes. ..... [8] J Z Jiang, J S Staun Olsen, L Gerward and S Morup, Europhys. Lett.

  15. Seo et al., Afr J Tradit Complement Altern Med. (2013) 10 (1):113-123

    African Journals Online (AJOL)

    AJTCAM

    huo-tang, Jiin-koka-to, Simultaneous determination. Introduction. Many herbal formulae have been used to prevent and treat various diseases. Such herbal medicines have few side effects and exhibit multiple activities (Zhang et al., 2004; Jiang, ...

  16. Association between ALDH 2 Glu504Lys polymorphism and ...

    African Journals Online (AJOL)

    : a meta-analysis. Jiang Xinhua, Zhao Yanfei. Abstract. Background: The findings from studies on the relationship between aldehyde dehydrogenases(ALDH) gene Glu504Lys polymorphism and colorectal cancer(CRC) were inconsistent.

  17. Distribution of organochlorine pesticides and polychlorinated ...

    African Journals Online (AJOL)

    SARAH

    2015-04-30

    Apr 30, 2015 ... compartments of the environment (soil, water, air.) (Wu et al., 1999, Jiang ... toxicity and bioaccumulation through the food chain and their long-range ... they are used for fisheries, aquaculture, touristic and transport activities.

  18. Dysregulated microRNA activity in Shwachman-Diamond Syndrome

    Science.gov (United States)

    2017-09-01

    Products Publications, conference papers, and presentations Joyce CE, Saadatpour A, Jiang L, Ruiz-Gutierrez M, Vargel Bolukbasi O, Hofmann I...Annual Meeting, San Diego, CA, 2016. Joyce CE, Li S, Hofmann I, Nusbaum C, Sieff C, Mason CE, Novina CD. “Single cell transcriptomic analysis of...hematopoietic dysfunction in Shwachman-Diamond Syndrome”. Poster, Keystone Hematopoiesis, Keystone, CO, 2015. Joyce CE, Jiang L, Hofmann I, Nusbaum C

  19. Looking closer at the Congo

    DEFF Research Database (Denmark)

    Jansson, Johanna; Jiang, Wenran

    2011-01-01

    An NGO report on Chinese investment in the Democratic Republic of Congo opens a vital debate, but its methodology leaves the reader wanting a fuller version of the facts, write Johanna Jansson and Jiang Wenran.......An NGO report on Chinese investment in the Democratic Republic of Congo opens a vital debate, but its methodology leaves the reader wanting a fuller version of the facts, write Johanna Jansson and Jiang Wenran....

  20. Hydrological River Drought Analysis (Case Study: Lake Urmia Basin Rivers

    Directory of Open Access Journals (Sweden)

    Mohammad Nazeri Tahrudi

    2017-02-01

    to investigatethe accuracy of this method, 3 methods (moment, maximum likelihood and Logarithm of applied moment observations were used and 4 mentioned methods for all of rivers were calculated. The most river drought relating to Gadar-Chai river with 1742 million cubic meters low volume and the lowest of it relating to Mardoq-Chai river with 68 million cubic meters low volume in 10000 year return period. After Gadar-Chai river the most low volume of discharge relating the Zarineh-rood river. Two Zarineh-rood and Gadar-Chai rivers among other rivers have a higher average discharge. Log Normal III, Gamma, Wikeby and GEV distributions have a good fitting on river flows data and no difference in investigation models that corresponded with Mosaedi et al (13 and NazeriTahroudi et al (15. The results of Grifits (7 also introduced the Wikeby distribution has a better than Beta distribution. Lee (12 also with evaluation the rainfall frequency in the study the rainfall concentration properties in Chia-Nan (Taiwan introduced the Log Pearson type III as the best distribution function between the common distribution function. Results of Chi-Squared test in methods of parameter estimation showed that all methods are acceptable. Conclusion: Drought occurrence can be estimated bythe analysis of historical data for different regions and using the results of predicting problems can be reduced. In this research daily river flow of Lake Urmia basin applied to calculate drought volume of rivers. Log Pearson III distribution selected among current hydrological distribution functions for fitting drought volume of rivers. Using selected distribution function and Sundry Average Moment method for estimating parameters return period of drought from 2 to 10000 years extracted. Results showed that volume of drought for Shahar-chai , Barandoz-chai, Nazlu-Chai, Mahabad-Chai, Rozeh-Chai, Gadar-chai, Simineh-rood, Zola-chai, Aji-chai, Sofi-chai, Leilan-chai and Mardoq-chay rivers in the return

  1. Formation and psychometric evaluation of a health-related quality of life instrument for children living with HIV in India.

    Science.gov (United States)

    Das, Aritra; Detels, Roger; Afifi, Abdelmonem A; Javanbakht, Marjan; Sorvillo, Frank; Panda, Samiran

    2018-03-01

    In-depth interviews and focus group discussions were conducted to inform the development of an instrument to measure the health-related quality of life of children living with HIV. The QOL-CHAI instrument consists of four generic core scales of the "Pediatric Quality of Life Inventory" and two HIV-targeted scales-"symptoms" and "discrimination." A piloting exercise involving groups of children living with HIV and HIV-negative children born to HIV-infected parents provided evidence for the acceptable psychometric properties and usability of the instrument. It is expected that the QOL-CHAI can serve well as a brief, standardized, and culturally appropriate instrument for assessing health-related quality of life of Indian children living with HIV.

  2. ORF Alignment: NC_002754 [GENIUS II[Archive

    Lifescience Database Archive (English)

    Full Text Available , ... 5'-Deoxy-5'-Methylthioadenosine Phosphorylase Complex ... With Phosphate (Space Group P2...1) pdb|1JDS|E Chain E, ... 5'-Deoxy-5'-Methylthioadenosine Phosphorylase Complex ... With Phosphate (Space... ... With Phosphate (Space Group P21) pdb|1JDS|C Chain C, ... 5'-De...oxy-5'-Methylthioadenosine Phosphorylase Complex ... With Phosphate (Space Group P21) pdb|1JDS|B Chai...n B, ... 5'-Deoxy-5'-Methylthioadenosine Phosphorylase Complex ... With Phosphate (Space Group

  3. AFRRI (Armed Forces Radiobiology Research Institute) Reports, January, February, March 1987.

    Science.gov (United States)

    1987-04-01

    POUYSS .GUR, J., J. C. CHAMBARD, A. FRANCHI , S. PARIS, AND E.a modifier site. J. Bio. ChAI. 258: 9710-9716,1983. VAN OBBERGHEN-SCHILLING. Growth...amiloride after reduction of the K* gradient). This observation (10-4 M, trace d). The steady-state acidification level rules out nonspecific effects of...not rule out the potential for other P( effects in the hippocampus. This possibility deserves further investigation. I BelluZi. 0.. Biondi. C

  4. 50th Annual Technical Meeting of the Society of Engineering Science (SES)

    Science.gov (United States)

    2014-08-15

    2:00 PM 30 Sess Micr Tuesda ion Chai omecha y 8:00 - 8 rs: Dimit nics and S Georg :50 Salom ris Lagou ome Asp C e Weng ( Tuesday Award on 101...College of New York), Shahab Shojaei-Zadeh (Rutgers University), Kevin Connington (The Levich Institute), Jeffrey Morris (Levich Institute and Dept. of...Duisburg-Essen) MECHANICS OF FLUIDS AND THERMAL SYSTEMS Complex Fluids: Suspensions, Emulsions, and Gels Barus-Holley 160 Session Chairs Jeffrey Morris

  5. Cellules solaires de type hétérojonction en volume basées sur des copolymères à bande interdite étroite et sur des dérivés solubles du fullerène

    OpenAIRE

    Ibraikulov , Olzhas

    2016-01-01

    The chemical structure of organic semiconductors that are utilized in bulk heterojunction photovoltaic cells may strongly influence the final device performances. Thus, better understanding the structure-property relationships still remains a major task towards high efficiency. Within this framework, this thesis reports in-depth material investigations including charge transport, morphology and photovoltaic studies on various novel low band-gap copolymers. First, the impact of alkyl side chai...

  6. Main: 1QN6 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available itiation Factor Tfiid-1; Chain: A, B; Synonym: Tata-Box Factor 1, Tata Sequence-Binding Protein 1, Tbp1; Eng...ineered: Yes; Molecule: Dna (5'-D(*Gp*Cp*Tp*Ap*Tp*Ap*Ap*Tp*Ap*Gp*Gp*Gp*Cp*A)-3'); Chai...n: C, E; Molecule: Dna (5'-D(*Tp*Gp*Cp*Cp*Cp*Tp*Ap*Tp*Tp*Ap*Tp*Ap*Gp*C)-3'); Chain: D, F Tata Box-Bindi

  7. Main: 1QNB [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available itiation Factor Tfiid-1; Chain: A, B; Synonym: Tata-Box Factor 1, Tata Sequence-Binding Protein 1, Tbp1; Eng...ineered: Yes; Molecule: Dna (5'-D(*Gp*Cp*Tp*Ap*Tp*Ap*Ap*Ap*Tp*Gp*Gp*Gp*Cp*A)-3'); Chai...n: C, E; Molecule: Dna (5'-D(*Tp*Gp*Cp*Cp*Cp*Ap*Tp*Tp*Tp*Ap*Tp*Ap*Gp*C)-3'); Chain: D, F Tata Box-Bindi

  8. Main: 1QN5 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available itiation Factor Tfiid-1; Chain: A, B; Synonym: Tata-Box Factor 1, Tata Sequence-Binding Protein 1, Tbp1; Eng...ineered: Yes; Molecule: Dna (5'-D(*Gp*Cp*Tp*Ap*Tp*Ap*Ap*Gp*Ap*Gp*Gp*Gp*Cp*A)-3'); Chai...n: C, E; Molecule: Dna (5'-D(*Tp*Gp*Cp*Cp*Cp*Tp*Cp*Tp*Tp*Ap*Tp*Ap*Gp*C)-3'); Chain: D, F Tata Box-Bindi

  9. Main: 1EQK [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1EQK イネ Rice Oryza sativa L. Cysteine Proteinase Inhibitor-I Oryza Sativa Molecule: Oryzacystatin-I; Chai...n: A; Engineered: Yes Hydrolase Inhibitor K.Nagata, N.Kudo, K.Abe, S.Arai, M.Tanokura ...K.Nagata, N.Kudo, K.Abe, S.Arai, M.Tanokura Three-Dimensional Solution Structure Of Oryzacystatin-I, A Cyste

  10. Main: 1QNA [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available itiation Factor Tfiid-1; Chain: A, B; Synonym: Tata-Box Factor 1, Tata Sequence-Binding Protein 1, Tbp1; Eng...ineered: Yes; Molecule: Dna (5'-D(*Gp*Cp*Tp*Tp*Tp*Ap*Ap*Ap*Ap*Gp*Gp*Gp*Cp*A)-3'); Chai...n: C, E; Molecule: Dna (5'-D(*Tp*Gp*Cp*Cp*Cp*Tp*Tp*Tp*Tp*Ap*Ap*Ap*Gp*C)-3'); Chain: D, F Tata Box-Bindi

  11. Towards an Ontology-Driven Blockchain Design for Supply Chain Provenance

    OpenAIRE

    Kim, Henry M.; Laskowski, Marek

    2016-01-01

    An interesting research problem in our age of Big Data is that of determining provenance. Granular evaluation of provenance of physical goods--e.g. tracking ingredients of a pharmaceutical or demonstrating authenticity of luxury goods--has often not been possible with today's items that are produced and transported in complex, inter-organizational, often internationally-spanning supply chains. Recent adoption of Internet of Things and Blockchain technologies give promise at better supply chai...

  12. Report of Working Group 22 on Iron Supply and its Impact on Biogeochemistry and Ecosystems in the North Pacific Ocean

    OpenAIRE

    2013-01-01

    The Working Group on Iron Supply and its Impact on Biogeochemistry and Ecosystems in the North Pacific Ocean (WG 22) was established October 2007 under the direction of the Biological Oceanography Committee (BIO) and consisted of 20 members from all PICES member countries, including Co-Chairmen, Drs. Shigenobu Takeda (Japan) and Fei Chai (USA). The purpose of the Working Group was to examine the role of iron biogeochemistry and its impact on biological productivity and marine ecosystems. WG 2...

  13. The Reasons of Young Consumers’ Choice on Chain Café Stores: A Research on Starbucks

    OpenAIRE

    Akgün, Serkan; Yalım, Funda

    2015-01-01

    Corporations providing services and making goods are forced to ensure customer satisfaction, to build brand loyalty, to change the way being in service by taking some changes into consideration, such as changes in living conditions, in consumers’ supply and demand, fi erce competition environment. At this point, chain café stores are appeared as preferred ones by especially young consumers in direct proportion to changes in consumers’ supply and demand. Young consumers, while going for a chai...

  14. Synthesis And Characterization Of Telechelic Polytetrahydrofuran

    OpenAIRE

    Temelkaya, Ecem

    2013-01-01

    The target of this study was to obtain polymers having different functional end groups with the combination of living cationic ring-opening polymerization and click chemistry methods including Cu(I)-catalyzed azide-alkyne cyclo-addition (CuAAC) reactions. In this sense, polytetrahydrofurans (PTHF) having various functionalities such as azide (-N3), hydroxyl (-OH), bromo (-Br) and anthracene were obtained using functionalization from initiator, functionalization from terminating agent and chai...

  15. EFFECTIVE OUTSOURCING THROUGHOUT THE SUPPLY CHAIN IN THE AUTOMOTIVE INDUSTRY

    OpenAIRE

    Liu, Ying

    2010-01-01

    The purpose of this bachelor’s thesis was to find a method of using outsourcing effectively throughout the supply chain in the automotive industry. Through the data collecting and analyzing, this thesis was written totally based on theory. As the automotive industry has been developing, the outsourcing service has become one of the most popular methods to improve the supply chain management. The auto manufacturer and spare parts supplier are the two most important roles in the supply chai...

  16. Role of Information in an SME in a Local Food Supply Chain - Case Study of a Norwegian Craft Beer Retailer

    OpenAIRE

    Vallandingham, Logan Reed; Sangachhen, Surendra

    2016-01-01

    Demand for locally produced food is increasing and the industry is gaining increased attention. But, many challenges are present for actors in local food supply chains (LFSC), and are especially related to limited capacity. Balancing supply and demand of their products is thusly extremely important in regards to inventory management and replenishment decisions. Local food actors, often small and medium enterprises (SMEs), especially need to reduce costs in order to be competitive. Supply chai...

  17. Physical-Biological-Optics Model Development and Simulation for the Pacific Ocean and Monterey Bay, California

    Science.gov (United States)

    2012-09-30

    distribution of underwater light field that can substantially affect phytoplankton photosynthesis and shortwave radiation near the surface. To...from Chai et al. (2002) was modified to include 31 state variables (Figure 1). With these new variables, the model can simulate photosynthesis ...improved by adding the dissolved pool and bacterial dynamics in the model. CDOC modeled as a colored byproduct of dissolved organic carbon (DOC) is

  18. Electron trapping and acceleration by the plasma wakefield of a self-modulating proton beam

    OpenAIRE

    Lotov, K. V.; Sosedkin, A. P.; Petrenko, A. V.; Amorim, L. D.; Vieira, J.; Fonseca, R. A.; Silva, L. O.; Gschwendtner, E.; Muggli, P.

    2014-01-01

    This paper has a conceptual character and explores an approach between transaction cost analysis theory and network theory when applied to supply chains in a broader context: industrial management research. This approach raises the assumptions that fast supply chains, i.e., supply chains made of short time relationships and multiple partners can contribute to destroying trust and collaboration between companies, ending up by stressing actual systems’ arrangements in somehow stable supply chai...

  19. Seasonal variation and natural infection of Lutzomyia antunesi (Diptera: Psychodidae: Phlebotominae), an endemic species in the Orinoquia region of Colombia

    OpenAIRE

    Trujillo, Adolfo Vasquez; Reina, Angelica E Gonzalez; Orjuela, Agustin Gongora; Suarez, Edgar Prieto; Palomares, Jairo Enrique; Alvarez, Luz Stella Buitrago

    2013-01-01

    Lutzomyia antunesi has been commonly reported in outbreaks of cutaneous leishmaniasis (CL) in the Orinoquia region of Colombia. The bionomics of this species were studied in the municipality of Villavicencio (Meta, Colombia). Sandflies were captured over the course of one week per month for one year in intradomiciliary, peridomiciliary and extradomiciliary housing areas. The captures were performed from 06:00 pm-06:00 am using CDC light traps and the females were processed for polymerase chai...

  20. Enhancing agricultural productivity and rural incomes through sustainable use of natural resources in the semi arid tropics.

    Science.gov (United States)

    Wani, Suhas P; Dixin, Yin; Li, Zhong; Dar, William D; Chander, Girish

    2012-03-30

    A participatory watershed management approach is one of the tested, sustainable and eco-friendly options to upgrade rain-fed agriculture to meet growing food demand along with additional multiple benefits in terms of improving livelihoods, addressing equity issues and biodiversity concerns. Watershed interventions at study sites in Thailand (Tad Fa and Wang Chai) and India (Kothapally) effectively reduced runoff and the associated soil loss. Such interventions at Xiaoxincun (China) and Wang Chai improved groundwater recharging and availability. Enhanced productive transpiration increased rainwater use efficiency for crop production by 13-29% at Xiaoxincun; 13-160% at Lucheba (China), 32-37% at Tad Fa and 23-46% at Wang Chai and by two to five times at Kothapally. Watershed interventions increased significantly the additional net returns from crop production as compared with the pre-watershed intervention period. Increased water availability opened up options for crop diversification with high-value crops, including increased forage production and boosted livestock-based livelihoods. In dryland tropics, integrated watershed management approach enabled farmers to diversify the systems along with increasing agricultural productivity through increased water availability, while conserving the natural resource base. Household incomes increased substantially, leading to improved living and building the resilience of the community and natural resources. Copyright © 2011 Society of Chemical Industry.

  1. Interface engineering in inorganic hybrid structures towards improved photocatalysis (Conference Presentation)

    Science.gov (United States)

    Xiong, Yujie

    2016-10-01

    Designing new photocatalytic materials for improving photoconversion efficiency is a promising route to alleviate the steadily worsening environmental issues and energy crisis. Despite the invention of a large number of catalytic materials with well-defined structures, their overall efficiency in photocatalysis is still quite limited as the three key steps - light harvesting, charge generation and separation, and charge transfer to surface for redox reactions - have not been substantially improved. To improve each step in the complex process, there is a major trend to develop materials based on inorganic hybrid structures. In this case, interface engineering holds the promise for boosting the overall efficiency, given the key roles of interface structures in charge and energy transfer. In this talk, I will demonstrate several different approaches to designing inorganic hybrid structures with improved photocatalytic performance via interface engineering. The typical demonstrations include semiconductor-plasmonics systems for broad-spectrum light harvesting, metal-semiconductor interfaces for improved charge separation, semiconductor-MOF (metal-organic framework) configurations for activated surface reactions. It is anticipated that this series of works open a new window to rationally designing inorganic hybrid materials for photo-induced applications. References: (1) Bai, S.; Yang, L.; Wang, C.; Lin, Y.; Lu, J.; Jiang, J. and Xiong, Y.*, Angew. Chem. Int. Ed. 54, 14810-14814 (2015). (2) Bai, S.; Jiang, J.; Zhang, Q. and Xiong, Y.*, Chem. Soc. Rev. 44, 2893-2939 (2015). (3) Bai, S.; Li, X.; Kong, Q.; Long, R.; Wang, C.; Jiang, J. and Xiong, Y.*, Adv. Mater. 27, 3444-3452 (2015). (4) Bai, S.; Ge, J.; Wang, L.; Gong, M.; Deng, M.; Kong, Q.; Song, L.; Jiang, J.;* Zhang, Q.;* Luo, Y.; Xie, Y. and Xiong, Y.*, Adv. Mater. 26, 5689-5695 (2014). (5) Li, R.; Hu, J.; Deng, M.; Wang, H.; Wang, X.; Hu, Y.; Jiang, H. L.; Jiang, J.;* Zhang, Q.;* Xie, Y. and Xiong, Y.*, Adv. Mater

  2. On an Objective Basis for the Maximum Entropy Principle

    Directory of Open Access Journals (Sweden)

    David J. Miller

    2015-01-01

    Full Text Available In this letter, we elaborate on some of the issues raised by a recent paper by Neapolitan and Jiang concerning the maximum entropy (ME principle and alternative principles for estimating probabilities consistent with known, measured constraint information. We argue that the ME solution for the “problematic” example introduced by Neapolitan and Jiang has stronger objective basis, rooted in results from information theory, than their alternative proposed solution. We also raise some technical concerns about the Bayesian analysis in their work, which was used to independently support their alternative to the ME solution. The letter concludes by noting some open problems involving maximum entropy statistical inference.

  3. Fast Multiscale Algorithms for Wave Propagation in Heterogeneous Environments

    Science.gov (United States)

    2016-01-07

    Leslie Greengard, Thomas Hagstrom, Shidong Jiang . Extension of the Lorenz–Mie– Debye method forelectromagnetic scattering to the time-domain, Journal of...Φ ∂z +ΣΦ = 0, where Φ is a vector of length m(p+1) for a boundary condition order of p and a hyperbolic system with m independent variables. Here...exterior of a sphere. J. Comput. Phys., 274:191–207, 2014. [19] L. Greengard, T. Hagstrom, and S. Jiang. Extension of the Lorenz-Mie- Debye method for

  4. Water Activated Doping and Transport in Multilayered Germanane Crystals

    Science.gov (United States)

    2015-09-21

    Justin Young, Basant Chitara , Nicholas Cultrara , Maxx Q Arguilla , Shishi Jiang, Fan Fan , Ezekiel Johnston-Halperin, Joshua E Goldberger 611102 c...Crystals Justin R Young1, Basant Chitara2, Nicholas D Cultrara2, Maxx Q Arguilla2, Shishi Jiang2, Fan Fan2 Ezekiel Johnston-Halperin1, Joshua E...Optoelectronics ACS Nano 7 5660-5 [9] Zhang Y, Tan Y-W, Stormer H L and Kim P 2005 Experimental observation of the quantum Hall effect and Berry’s phase in

  5. Vatuximab(Trademark): Optimizing Therapeutic Strategies for Prostate Cancer Based on Dynamic MR Tumor Oximetry

    Science.gov (United States)

    2010-01-01

    159: 621-631, 2003. 37. Bourke , V. A., Zhao, D., Gilio, J., Chang, C.-H., Jiang, L., Hahn, E. W., and Mason, R. P. Correlation of Radiation...probe: comparison with a paired survival assay. Radiat Res, 158, 167-73 (2002) 27. Gu, Y. Q., V. A. Bourke , J. G. Kim, A. Constantinescu, R. P. Mason...Res. 1998; 150: 549–556. 10. Bourke VA, Zhao D, Gilio J, Chang C-H, Jiang L, Hahn EW, Mason RP. Correlation of radiation response with tumor oxygen

  6. Identification of Genes and Genetic Variants Associated with Poor Treatment Response in Patients with Prostate Cancer

    Science.gov (United States)

    2012-10-01

    gene DAL-1 (Jiang and Newsham, 2006). The gene NELL1 ( Homo sapiens NEL-like 1) may be involved in cell growth regulation and differentiation by...interval for the pedigree linked to chromosome 11 occurs approximately 34-46 cM. This region contains 13 currently documented genomic features , several

  7. Erratum: Back reaction, emission spectrum and entropy spectroscopy

    Science.gov (United States)

    Jiang, Qing-Quan; Cai, Xu

    2012-06-01

    In our paper [Qing-Quan Jiang and Xu Cai, Back reaction, emission spectrum and entropy spectroscopy, JHEP 11 (2010) 066], there was an error in using the first law of black hole thermodynamic and the Bohr-Sommerfeld quantization rule. In this erratum, we attempt to rectify them.

  8. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Jiandong Wu1 Xiaolei Jin1 Yang Zhao1 Qing Dong1 Haiyang Jiang1 Qing Ma1. Key Laboratory of Crop Biology of Anhui Province, School of Life Sciences, Anhui Agricultural University, Hefei 230036, People's Republic of China ...

  9. Bulletin of Materials Science | News

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 39; Issue 5. Effects of size on mass density and its influence on mechanical and thermal properties of ZrO 2 nanoparticles in different structures. BOTAN JAWDAT ABDULLAH QING JIANG MUSTAFA SAEED OMAR. Volume 39 Issue 5 September 2016 pp 1295-1302 ...

  10. L2 Chinese: Grammatical Development and Processing

    Science.gov (United States)

    Mai, Ziyin

    2016-01-01

    Two recent books (Jiang, 2014, "Advances in Chinese as a second language"; Wang, 2013, "Grammatical development of Chinese among non-native speakers") provide new resources for exploring the role of processing in acquiring Chinese as a second language (L2). This review article summarizes, assesses and compares some of the…

  11. AMULET: A MUlti-cLuE Approach to Image Forensics

    Science.gov (United States)

    2014-12-31

    celebrities have been substituted in the other two pictures. 3.2.5 Choice of reliability properties Let us now apply the BBA mapping approach proposed in...Jiang, and L. Ma, “Ds evidence theory based digital image trustworthiness evaluation model,” in MINES 2009, International Conference on Multimedia

  12. Nutrition Research Agenda in the Context of Nutrition Problems in ...

    African Journals Online (AJOL)

    2010-04-02

    Apr 2, 2010 ... health metrics are used to assess overall food. Nutrition Research ... or dietary planning although use of a diet quality ...... Jiang, Y., Jolly, P.E., Preko, P., Wang, J.S.,. Ellis, W.O. ... Hindawi Publishing Corporation, Article.

  13. Evolution of the defensin-like gene family in grass genomes

    Indian Academy of Sciences (India)

    . Jiandong Wu, Xiaolei Jing, Yang Zhao, Qing Dong, Haiyang Jiang and Qing Ma. J. Genet. 95, 53–62. Table 1. Information about DEFL genes in B. distachyon, O. sativa, S. bicolor and Z. mays. Species. Gene name. Gene identifer. ORF (aa).

  14. Ecohealth Field-building Leadership Initiative in Southeast Asia ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Institution. Kunming Institute of Botany, Chinese Academy of Sciences as represented by Sun Hang. Institution Country. China. Project Leader. Dr Fang Jing. Institution. Kunming Medical University as represented by Jiang Runsheng. Institution Country. China. Institution Website. http://www.kmmu.edu.cn. Project Leader.

  15. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Haiyang Dai1 Changyong Zhan2 Hui Jiang2 Ningkang Huang2. Department of Technology and Physics, Zhengzhou University of Light Industry, Zhengzhou 450002, P. R. China; Key Laboratory of Radiation and Technology of Education Ministry of China, Institute of Nuclear Science and Technology, Sichuan University, ...

  16. Journal of Astrophysics and Astronomy | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... Author Affiliations. J. B. Su1 Z.-Q. Shen1 X. Chen1 Jiyune Yi2 D. R. Jiang1 Y. J. Yun3. Shanghai Astronomical Observatory, Chinese Academy of Sciences, Shanghai 200030, China. Korea Astronomy and Space Science Institute, Daejeon 305-348, South Korea. Department of Physics and Astronomy, ...

  17. Characterization and photocatalytic activity of boron-doped TiO2 thin ...

    Indian Academy of Sciences (India)

    Wintec

    Chen Daimai, Wang Dong Yang and Jiang Zhongyi 2006 Ind. Eng. Chem. 45 4110. Cheng Jen-hao 2003 A study on photocatalytic oxidation of aque- ous chlorobenzene solution by nanostructured film of TiO2,. Master Thesis, National Sun Yat-Sen University, Taiwan. Deki S, Henin Yu Yu Ko, Fujita T, Akamatsu K, Mizuhata ...

  18. Proceedings – Mathematical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    The discreteness of isometry groups in complex hyperbolic space is a fundamental problem. In this paper, the discreteness criteria of a -dimensional subgroup of S U ( n , 1 ) are investigated by using a test map which may not be in . Author Affiliations. Huani Qin1 2 Yueping Jiang1. College of Applied Mathematics, ...

  19. Quantum tunneling, adiabatic invariance and black hole spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Li, Guo-Ping; Zu, Xiao-Tao [University of Electronic Science and Technology of China, School of Physical Electronics, Chengdu (China); Pu, Jin [University of Electronic Science and Technology of China, School of Physical Electronics, Chengdu (China); China West Normal University, College of Physics and Space Science, Nanchong (China); Jiang, Qing-Quan [China West Normal University, College of Physics and Space Science, Nanchong (China)

    2017-05-15

    In the tunneling framework, one of us, Jiang, together with Han has studied the black hole spectroscopy via adiabatic invariance, where the adiabatic invariant quantity has been intriguingly obtained by investigating the oscillating velocity of the black hole horizon. In this paper, we attempt to improve Jiang-Han's proposal in two ways. Firstly, we once again examine the fact that, in different types (Schwarzschild and Painleve) of coordinates as well as in different gravity frames, the adiabatic invariant I{sub adia} = circular integral p{sub i}dq{sub i} introduced by Jiang and Han is canonically invariant. Secondly, we attempt to confirm Jiang-Han's proposal reasonably in more general gravity frames (including Einstein's gravity, EGB gravity and HL gravity). Concurrently, for improving this proposal, we interestingly find in more general gravity theories that the entropy of the black hole is an adiabatic invariant action variable, but the horizon area is only an adiabatic invariant. In this sense, we emphasize the concept that the quantum of the black hole entropy is more natural than that of the horizon area. (orig.)

  20. African Journal of Biotechnology - Vol 10, No 35 (2011)

    African Journals Online (AJOL)

    Interspecific hybridization between Mauremys reevesii and Mauremys sinensis: Evidence from morphology and DNA sequence data · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. X Xia, L Wang, L Nie, Z Huang, Y Jiang, W Jing, L Liu, 6716-6724 ...

  1. dimensional nonlinear Schrödinger equation with spatially

    Indian Academy of Sciences (India)

    Hong-Yu Wu

    2017-08-16

    Aug 16, 2017 ... HONG-YU WU. ∗ and LI-HONG JIANG ... Our present work provides a detailed answer to these questions. ... with the self-consistency condition |Y(θ,ϕ)|2 = 1. Equation (4) .... [4] L Q Kong and C Q Dai, Nonlinear Dyn. 81, 1553 ...

  2. African Journal of Biotechnology - Vol 10, No 7 (2011)

    African Journals Online (AJOL)

    Effects of deoxycycline induced lentivirus encoding FasL gene on apoptosis of Th1 cells · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. H Luo, T Wang, A Luo, J Wang, Y Zhao, H Jiang, Q Shi, 1081-1087 ...

  3. AUTHOR INDEX

    Indian Academy of Sciences (India)

    Wintec

    Two different zinc(II)-aqua complexes held up by a metal-oxide based ... simple conversion to metal-carbon composites 579. De G see Medda S K. 565. Dey Shantanu .... electrode for the determination of trace Cr(VI) 493. Liu F see Jiang W.

  4. Manyame River Basin, Zimbabwe

    African Journals Online (AJOL)

    2016-01-01

    Jan 1, 2016 ... an important driver of ecosystem structure and functions in reservoirs. ..... In Lake. Chivero, silt/clay consisting of fine organic substrates was the ..... LAI X, HUANG Q, ZHANG Y and JIANG J (2014) Impact of lake inflow and the ...

  5. Browse Title Index

    African Journals Online (AJOL)

    Items 501 - 550 of 1309 ... HH Tamboura, B Bayala, M Lompo, IP Guissou, L Sawadogo ... X Wang, Y-G Chen, L Ma, Z-H Li, J-Y Li, X-G Liu, J-L Zou, J-H Wu. Vol 11, No 2 ... Zhi-Jiang Wang, Wei Xu, Jian-Wen Liang, Cai-Sheng Wang, Yani Kang.

  6. Investigation of the Effects of Expectation Values for Radii on the ...

    Indian Academy of Sciences (India)

    mation (NCA) wave functions to calculate expectation values of radii. The transition probability ... 1. Introduction. The optical properties of carbon, nitrogen and oxygen atoms are important in both atmospheric and ...... Zheng, N. W. 1988a, A new outline of atomic theory (Jiang Su Education Press). Zheng, N. W. 1988b, Chin.

  7. Mixed contaminant interactions in soil: Implications for bioavailability ...

    African Journals Online (AJOL)

    user

    Liu H, Zhang D, Li M, Tong L, Feng L (2013b). Competitive adsorption and transport of phthalate esters in the clay layer of JiangHan plain,. China. Chemosphere 92(11):1542-1549. Loffredo E, Senesi N (2006). Fate of anthropogenic organic pollutants in soils with emphasis on adsorption/desorption processes of endocrine.

  8. Quantum tunneling, adiabatic invariance and black hole spectroscopy

    Science.gov (United States)

    Li, Guo-Ping; Pu, Jin; Jiang, Qing-Quan; Zu, Xiao-Tao

    2017-05-01

    In the tunneling framework, one of us, Jiang, together with Han has studied the black hole spectroscopy via adiabatic invariance, where the adiabatic invariant quantity has been intriguingly obtained by investigating the oscillating velocity of the black hole horizon. In this paper, we attempt to improve Jiang-Han's proposal in two ways. Firstly, we once again examine the fact that, in different types (Schwarzschild and Painlevé) of coordinates as well as in different gravity frames, the adiabatic invariant I_adia = \\oint p_i dq_i introduced by Jiang and Han is canonically invariant. Secondly, we attempt to confirm Jiang-Han's proposal reasonably in more general gravity frames (including Einstein's gravity, EGB gravity and HL gravity). Concurrently, for improving this proposal, we interestingly find in more general gravity theories that the entropy of the black hole is an adiabatic invariant action variable, but the horizon area is only an adiabatic invariant. In this sense, we emphasize the concept that the quantum of the black hole entropy is more natural than that of the horizon area.

  9. Comment on 'Modelling of surface energies of elemental crystals'

    International Nuclear Information System (INIS)

    Li Jinping; Luo Xiaoguang; Hu Ping; Dong Shanliang

    2009-01-01

    Jiang et al (2004 J. Phys.: Condens. Matter 16 521) present a model based on the traditional broken-bond model for predicting surface energies of elemental crystals. It is found that bias errors can be produced in calculating the coordination numbers of surface atoms, especially in the prediction of high-Miller-index surface energies. (comment)

  10. African Journal of Biotechnology - Vol 5, No 11 (2006)

    African Journals Online (AJOL)

    Seperation, identification and analysis of pigment (melanin) production in Streptomyces · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. SG Dastager, WJ Li, A Dayanand, S-K Tang, X-P Tian, X-Y Zhi, L-H Xu, C-L Jiang ...

  11. Persistent use of a shorebird staging site in the Yellow Sea despite severe declines in food resources implies a lack of alternatives

    NARCIS (Netherlands)

    Zhang, Shou-Dong; Ma, Zhijun; Choi, Chi-Yeung; Peng, He-Bo; Bai, Qing-Quan; Liu, Wen-Liang; Tan, Kun; Melville, David S.; He, Peng; Chan, Ying-Chi; Piersma, Theunis; van Gils, Jan A.

    2018-01-01

    Many shorebird populations are in decline along the East Asian-Australasian Flyway. The rapid loss of coastal wetlands in the Yellow Sea, which provide critical stop-over sites during migration, is believed to be the cause of the alarming trends. The Yalu Jiang coastal wetland, a protected area in

  12. Identification and Classification of Player Types in Massive Multiplayer Online Games Using Avatar Behavior

    Science.gov (United States)

    2011-08-01

    Kuan-Ta, Jhih-Wei Jiang, Polly Huang, Hao-Hua Chu, Chin-Laung Lei, and Wen-Chin Chen, “Identifying MMORPG Bots: A Traffic Analysis Approach”, EURASIP...in MMORPGs ”, Proceedings of DiGRA 2005 Conference: Changing Views – Worlds in Play Loeffelholz, Bernard, Earl Bednar, Kenneth W. Bauer, “Predicting

  13. Anti-Thrombotic Effect of Carthamus tinctorius Linn Extracts in Rats

    African Journals Online (AJOL)

    HP

    Safflower, Carthamus tinctorius Linne). Neurochem. Res. 2009; 34: 795–. 805. 8. Zhang SQ, Jiang LD. Effect of safflower injection on cardiac energy charge and anti-apoptosis gene bcl-2 in rats' heart.Chin. J. Integr. Tradit. West. Med. 2004;.

  14. SHORT COMMUNICATION DETERMINATION OF CYPERMETHRIN ...

    African Journals Online (AJOL)

    Preferred Customer

    Spectra-physics SP8810 HPLC, equipped with UV detector; N-1NW revolving evaporator (Tokyo Physics and Chemistry Company, Japan); high-speed homogenizer (German. IKA Company); HY-4 timing multi-oscillator (JiangSu JinSheng Apparatus Factory); T500 electronic balance (ChangShu Testing Apparatus Factory); ...

  15. Contextual Cueing in Multiconjunction Visual Search Is Dependent on Color- and Configuration-Based Intertrial Contingencies

    Science.gov (United States)

    Geyer, Thomas; Shi, Zhuanghua; Muller, Hermann J.

    2010-01-01

    Three experiments examined memory-based guidance of visual search using a modified version of the contextual-cueing paradigm (Jiang & Chun, 2001). The target, if present, was a conjunction of color and orientation, with target (and distractor) features randomly varying across trials (multiconjunction search). Under these conditions, reaction times…

  16. On the dual symmetry between absorbing and amplifying random ...

    Indian Academy of Sciences (India)

    (Paris), 48, 527 (1987). [20] C Vanneste and P Sebbah, Phys. Rev. Lett. 87, 183903 (2001). P Sebbah and C Vanneste, Phys. Rev. B66, 144202 (2002). [21] X Jiang and C M Soukoulis, Phys. Rev. Lett. 85, 70 (2000). [22] M Ya Azbel, Solid State Commun. 45, 527 (1983). [23] J B Pendry, A Mackinnon and P J Roberts, Proc.

  17. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Zhang Lei. Articles written in Bulletin of Materials Science. Volume 34 Issue 1 February 2011 pp 161-167. Characterization on strength and toughness of welded joint for Q550 steel · Jiang Qinglei Li Yajiang Wang Juan Zhang Lei · More Details Abstract Fulltext PDF. Q550 high ...

  18. Sensing of polymeric sensor-based rhodamine B derivative for metal ...

    Indian Academy of Sciences (India)

    TONG-MOU GENG1 XIE WANG1 FENG ZHU1 HUI JIANG1 YU WANG2. Collaborative Innovation Center for Petrochemical New Materials, Anhui Key Laboratory of Functional Coordination Compounds, School of Chemistry and Chemical Engineering, Anqing Normal University, Anqing 246011, People's Republic of China ...

  19. Molecular Profiles for Lung Cancer Pathogenesis and Detection in US Veterans

    Science.gov (United States)

    2011-10-01

    receptor blockade and knockdown reduced metastasis in animal models 81. Thus, blocking the COX-2-dependent PGE2 production or activity by targeting the... overpopulation during colon tumorigenesis. Cancer Res 2009;69:3382-3389 107. Jiang F, Qiu Q, Khanna A, et al. Aldehyde dehydrogenase 1 is a tumor

  20. Moment convergence rates in the law of the logarithm for dependent ...

    Indian Academy of Sciences (India)

    Inspired by Chow [3] and Jiang et al [6], here we consider the exact convergence rates in the law of the logarithm and Chung-type law of the logarithm for negatively associated. (NA) random variables including partial sums and the maximum of the partial sums. First, we shall give the definition of negatively associated ...

  1. Yi Tan

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Yi Tan. Articles written in Bulletin of Materials Science. Volume 38 Issue 5 September 2015 pp 1429-1433. Evaluation on electrical resistivity of silicon materials after electron beam melting · Hafiz Muhammad Noor Ul Huda Khan Asghar Shuang Shi Dachuan Jiang Yi Tan.

  2. An analysis of various scholarly approaches to the acquisition of Chinese characters by students of Chinese as a foreign language

    DEFF Research Database (Denmark)

    Ptaszynski, Signe Overgaard

    2007-01-01

    Wang Bixia et al. (1997) and Jiang Liping (1998) investigated what learning strategies students of Chinese as a foreign language employ when learning Chinese characters. On the basis of their research they suggest what pedagogical methods the teacher should apply in order to make the task easier...

  3. Anti-tumor activity of polysaccharides extracted from Senecio ...

    African Journals Online (AJOL)

    *, Bao Zhang, Mingming Han, Xin Jin, Liyuan Sun and Tao Li. Department of ..... Yang J, Li X, Xue Y, Wang N, Liu W. Anti-hepatoma activity and mechanism of corn ... Peng W, Wu JG, Jiang YB, Liu YJ, Sun T, Wu N, Wu CJ. Antitumor activity of ...

  4. X-ray structure, hydrogen bonding and lattice energy analysis of (2E ...

    Indian Academy of Sciences (India)

    tion data for both the compounds were collected on an X'Calibur CCD area detector diffractometer (Oxford Diffrac- tion) using MoKa .... (Oxford Diffraction make, U.K.) ..... [4] Wang L, Chen G, Lu X, Wang S, Han S, Li Y, Ping G, Jiang. X, Li H ...

  5. Influences of protective atmosphere on the characterization and ...

    Indian Academy of Sciences (India)

    tective atmosphere on the characterization and properties of the ceramics were investigated. All the ceramics showed ... Tian-Hang Zhang et al temperature and ..... Soc. 24 3731. 20. Wang Y, Zhang Y C, Hu Z J, Gao X, Guo X F and Jiang Y J.

  6. Symplocaceae

    African Journals Online (AJOL)

    There are only few reports on the chemical composition of ... However, literature searches have shown no report on ..... Jiang J, Feng Z, Wang Y, Zhang P. New phenolics from the roots of ... Song J, Li N, Xia Y, Gao Z, Zou SF, Kong L, Yao YJ, Jiao. YN, Yan YH ... Han YH, Kee JY, Park J, Kim HL, Jeong MY, Kim DS,. Jeon YD ...

  7. Download this PDF file

    African Journals Online (AJOL)

    pc

    2017-11-10

    Nov 10, 2017 ... ts of alkyl chain length on particles morphology were primarily studied ..... [3] Li Z, Yu L, Zheng L, Li N, Han S, Li G. Characterization studies on the ionic ... [4] Chiang YD, Lian HY, Leo SY, Wang SG, Yamauchi Y, Wu KC. ... [20] Yu YJ, Xing JL, Pang JL, Jiang SH, Lam KF, Yang TQ, Xue QS, Zhang K, Wu P.

  8. A new characterization of L2 (p) by NSE

    Indian Academy of Sciences (India)

    In this paper we give a new characterization of simple group 2() with a prime by both its order and (2()), the set of numbers of elements of 2() with the same order. Author Affiliations. Qinhui Jiang1 Changguo Shao1. School of Mathematical Sciences, University of Jinan, 250022 Shandong, China. Dates.

  9. African Journal of Traditional, Complementary and Alternative ...

    African Journals Online (AJOL)

    Li-Long Liu, Kai Xu, Lu-Mei Kang, Shu-Ping Jiang, Qing-Hua Wang, Lei Zhang, Shao-Gui Wan, Hong-Ping Chen, 113-121 ... Cytological effects of pulsed electromagnetic fields and static magnetic fields induced by a therapeutic device on in vivo exposed rats · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  10. AMACR is not applicable as a diagnostic tool in hepatocellular carcinoma

    DEFF Research Database (Denmark)

    Willemoe, Gro Linno; Vainer, Ben

    2010-01-01

    that the demonstration of AMACR expression or its pattern of distribution is useful in the diagnosis of hepatocellular carcinoma (HCC) (Jiang et al., Hum Pathol 2003;34, Guzman et al., Appl Immunohistochem Mol Morphol 2006;14, Li et al., J Exp Clin Cancer Res 2008;27). The aim of the present study was to evaluate...

  11. Monitoring of uncultured Dunaliella sp. in an Egyptian solar saltern ...

    African Journals Online (AJOL)

    FJ-USER

    2013-08-21

    Aug 21, 2013 ... salinity, pH, light intensity and temperature. The characterization of economically important algae in solar salterns has become a key focus for many research groups all over the world (Chen and Jiang, 2009). Dunaliella species that are living in these fields, have an economic importance due to its highly ...

  12. Lnc-ing inflammation to disease

    CSIR Research Space (South Africa)

    Magagula, L

    2017-08-01

    Full Text Available by RNAi more than by antisense oligonucleotides. Nucleic Acids Res. 44, 863–877 doi:10.1093/nar/gkv1206 75 Zhen, S., Hua, L., Liu, Y.-H., Sun, X.-M., Jiang, M.-M., Chen, W. et al. (2017) Inhibition of long non-coding RNA UCA1 by CRISPR/Cas9 attenuated...

  13. The Voice of Feedback: A Study of Asynchronous Audio Communication in the Online Classroom

    Science.gov (United States)

    Johnson Van Den Elzen, Jolene M.

    2011-01-01

    The interaction between learners and the instructor in an online learning environment has been shown to contribute to increases in learning through promotion of a cooperative and collaborative environment, which allows students to learn from course materials, the instructor, and each other (Jiang & Ting, 2000; Jung et al., 2002; Kollock, 1998;…

  14. Stress Controlled Catalysis via Engineered Nanostructures

    Science.gov (United States)

    2016-03-02

    Copenhagen Nicholas Dee Massachusetts Institute of Technology Francsico Schunk Brown University Ronald Dunn Brown University Bo Shen Brown University...Institute of Technology Zheng Jie Tan Massachusetts Institute of Technology Daniel Janda Brown University Andre D. Taylor Yale University Rongzhong Jiang U.S

  15. Electrochemical behaviour of superhydrophobic coating fabricated ...

    Indian Academy of Sciences (India)

    ties make it useful in household and industrial fields such as marine, automotive and ... are its simplicity, more cost effectiveness and less complex condition to .... Li M, Zhai J, Liu H, Song Y, Jiang L and Zhu D 2003 J. Phys. Chem. B 107 9954.

  16. Exploring and Listening to Chinese Classical Ensembles in General Music

    Science.gov (United States)

    Zhang, Wenzhuo

    2017-01-01

    Music diversity is valued in theory, but the extent to which it is efficiently presented in music class remains limited. Within this article, I aim to bridge this gap by introducing four genres of Chinese classical ensembles--Qin and Xiao duets, Jiang Nan bamboo and silk ensembles, Cantonese ensembles, and contemporary Chinese orchestras--into the…

  17. Verification of the utility of molecular markers linked to the multiple ...

    African Journals Online (AJOL)

    GREGORY

    2010-08-30

    Aug 30, 2010 ... Feng Hui*, Wang Lili, Wei Peng, Liu Zhiyong, Li Chengyu, Wang Yugang, Ji Ruiqin and Zhang. Huaqing ..... Chin. Agric. Sci. Bull. 22: 377-379. Li CY, Feng H, Wei P, Wang LL, Zhang J, Yang HN, Jiang N (2009). Directional transfer of the genic multiple allele inherited male sterile line in Chinese cabbage.

  18. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Yan Jiang1 2 Bo Tian1 2 Pan Wang1 2 Kun Su1 2. State Key Laboratory of Information Photonics and Optical Communications, Beijing University of Posts and Telecommunications, Beijing 100876, China; School of Science, Beijing University of Posts and Telecommunications, Beijing 100876, China ...

  19. China to Step up Supervision of Futures Market

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    China will intensify its supervision and regulation of the futures market,and severely crack down on insider trading and market manipulation,according to the country’ssecurities regulator. Jiang Yang,Assistant to Chairman of the China Securities Regulatory Commission(CSRC),said Friday at the sixth International

  20. Chronic inflammatory cells and damaged limbal cells in pterygium

    African Journals Online (AJOL)

    EB

    2013-09-03

    Sep 3, 2013 ... Objective: To explain chronic inflammation in pterygium, and to clarify whether damaged limbal basal epithelial cells were ..... Jiang Y, Goldberg ID, Shi YE. Complex roles of tissue inhibitors of metalloproteinases in cancer. Oncogene 2002; 21: 2245-2252. 6. Kato S, Aoshima H, Saitoh Y, Miwa N. Fullerene-.

  1. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics; Volume 93; Issue 1. Molecular characterization and differential expression of two duplicated odorant receptor genes, AcerOr1 and AcerOr3, in Apis cerana cerana. Huiting Zhao Pengfei Gao Haiyan Du Weihua Ma Songhao Tian Yusuo Jiang. Research Article Volume 93 Issue 1 April ...

  2. from the Giant Panda

    African Journals Online (AJOL)

    STORAGESEVER

    2009-06-03

    Jun 3, 2009 ... 1College of Life Science, China West Normal University, 44# Yuying Road, 637002, Nanchong, China. 2Zhan Jiang educational ... in Escherichia coli and the RPS28 protein fusioned with the N-terminally GST -tagged protein gave rise ... long Conservation Center of the Giant Panda, Sichuan, China. The.

  3. Download this PDF file

    African Journals Online (AJOL)

    cadewumi

    Physical Science, Chinese Academy of Science, Hefei 230031, China, 3Department of Clinical of Pharmacy, Lishui People's Hospital, Zhe Jiang. 323000, China ... Conclusion: XJEK therapy in the 2K1C hypertensive rats affects the rise in blood pressure and ameliorates the severity of kidney injury. The protective effect is ...

  4. Evaluation of insulin-like growth factor-I gene polymorphism in ...

    African Journals Online (AJOL)

    Tuoyo Aghomotsegin

    2016-11-30

    Nov 30, 2016 ... African Journal of Biotechnology. Full Length ... nucleotide sequences of alleles C and G in sheep and goat were submitted to GenBank with the accession ... reproduction traits in farm animals (Jiang et al., 2002;. Arora and ..... Characterization of small ruminant breeds in West Asia and North. Africa, Luis ...

  5. Scalable Algorithms for Parallel Discrete Event Simulation Systems in Multicore Environments

    Science.gov (United States)

    2013-05-01

    consolidated at the sender side. At the receiver side, the messages are deconsolidated and delivered to the appropriate thread. This approach bears some...Jiang, S. Kini, W. Yu, D. Buntinas, P. Wyckoff, and D. Panda . Performance comparison of mpi implementations over infiniband, myrinet and quadrics

  6. Modulation of Stat3 Alternative Splicing in Breast Cancer

    Science.gov (United States)

    2010-09-01

    using morpholino oligonucleotides covalently linked to an octaguanidine dendrimer (vivo- morpholinos) [54]. Since delivery of vivo-morpholino oligos...Li, and S. Jiang, Vivo-Morpholinos: a non-peptide transporter delivers Morpholinos into a wide array of mouse tissues. Biotechniques, 2008. 45(6

  7. Do cheaters in the lab also cheat in the field?

    NARCIS (Netherlands)

    Potters, Jan; Stoop, J.T.R.

    In this paper, we study the correlation between cheating in the lab and cheating in the field. We conduct a laboratory experiment using a variant of the Mind game (Jiang, 2013). Payoffs above a certain threshold are indicative of cheating behavior. Subjects are paid their earnings by bank transfer.

  8. Critical responses of photosynthetic efficiency in Campsis radicans ...

    African Journals Online (AJOL)

    use

    and annual accumulated temperature over 10°C is 2750°C The soil is classified as brown and cinnamon soil, with inferior development and severe water and soil erosion. The vegetation type is forest- steppe and shrub zones with little shrub species and most of woodland is open forest with low stability. Jiang-bao et al.

  9. C‑reactive Protein and Disease Outcome in Nigerian Sickle Cell ...

    African Journals Online (AJOL)

    Sillesen H, Nordestgaard BG. Genetically elevated C‑reactive protein and ischemic vascular disease. N Engl J Med. 2008;359:1897‑908. 18. Walter PB, Fung EB, Killilea DW, Jiang Q, Hudes M, Madden J, et al. Oxidative stress and inflammation in iron‑overloaded patients with beta‑thalassaemia or sickle cell disease. Br J.

  10. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... compounds: Part 15. Synthesis, anisochronism and the relationship between crystallographic and spectral data of monotopic spiro-crypta phosphazenes .... Hydrolytic cleavage of bis(-nitrophenyl) phosphate by Schiff base Mn complexes containing morpholine pendants in Gemini 16-6-16 micelles · Weidong Jiang Bin ...

  11. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 41; Issue 2. Effect of oxygen vacancies on Li-storage of anatase TiO 2 (001) facets: a first principles study. H CHEN Y H DING X Q TANG W ZHANG J R YIN P ZHANG Y JIANG. Volume 41 Issue 2 April 2018 Article ID 51 ...

  12. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 35; Issue 4. CuO/TiO2 nanocrystals grown on graphene as visible-light responsive photocatalytic hybrid materials. Yuan Fang Rijing Wang Guohua Jiang He Jin Yin Wang Xinke Sun Sheng Wang Tao Wang. Volume 35 Issue 4 August 2012 pp 495-499 ...

  13. Saturation mapping of QTL region determining resistance specificity ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-09-01

    Sep 1, 2009 ... S, Ni L, Zhu F, Chen W, Lan L, Lai Y, Cheng Z, Gu M, Jiang J, Li J,. Hong G, Xue Y, Han B ... Katagiri F, Markus Lange B, Moughamer T, Xia Y, Budworth P,. Zhong J, Miguel T, ... Gen. Genet. 261: 58-63. Marrs KA (1996).

  14. Research

    African Journals Online (AJOL)

    abp

    16 oct. 2017 ... Hong Jiang, Xu Qian, Guillermo Carroli and Paul Garner. Selective versus routine use of episiotomy for vaginal birth. Cochrane Database Syst Rev. 2017 February 8; 2: CD000081. Google Scholar. 17. Louis Kuhne. L'origine de la méthode Bain Detox in Bain de · désintoxication. Consulté le 15 avril 2017.

  15. Weixiong You

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. WEIXIONG YOU. Articles written in Bulletin of Materials Science. Volume 36 Issue 7 December 2013 pp 1147-1151. Yb and Er co-doped Y2Ce2O7 nanoparticles: synthesis and spectroscopic properties · Honghui Jiang Weixiong You Xiaolin Liu Jinsheng Liao Ping Wang Bin ...

  16. Tako-tsubo cardiomyopathy after a quarrel.

    African Journals Online (AJOL)

    Tako-tsubo cardiomyopathy after a quarrel. Dong-Mei Jiang1,a, Ze-Wei Sunc2,a, Jie Han2. 1. Department of Cardiology, Biomedical research (therapy) center, Sir Run Run Shaw Hospital,. College of ... acterized by (1) sudden onset of chest pain or shortness of breath; (2) ... In the present report, we de- scribe a case of ...

  17. Prevalence and associated factors of late HIV diagnosis in north ...

    African Journals Online (AJOL)

    User

    Moreover, there is still a lack of studies addressing the risk factors ..... Jiang, H., Yin, J., Fan, Y., Liu, J., Zhang, Z, Liu, L. & Nie, S. (2015) Gender difference in advanced HIV disease ... Incidence of HIV-associated tuberculosis among individuals taking combination antiretroviral therapy: a systematic review and meta-analysis.

  18. Hormonal Resistance and Metastasis: ER-coregulator-Src Signaling Targeted Therapy

    Science.gov (United States)

    2010-09-01

    Pestell RG, Hinds PW, Dowdy SF, Brown M, Ewen ME. Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4. Mol Cell Biol...Wright, J. A., Wu, K., Rui, H., Vadlamudi, R. K., Jiang, J., Kumar, R., Wang, C., and Pestell , R. G. (2009) The cell fate determination factor DACH1

  19. Modeling of Engine Parameters for Condition-Based Maintenance of the MTU Series 2000 Diesel Engine

    Science.gov (United States)

    2016-09-01

    particles in the analysis of engine oil samples (Jiang and Yan 2008). Lee monitors the exhaust gas temperature of the diesel engine for a roll-on...roll-off-passenger commercial vessel (Lee 2013). Jardine, Lin and Banjevic note other monitoring parameters, such as acoustic, moisture , humidity...expressed in terms of a constant y- intercept , , a disturbance, , an independent variable, , their past, −

  20. Studies on middle silkgland proteins of cocoon colour sex-limited ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 29; Issue 1. Studies on middle silkgland proteins of cocoon colour sex-limited silkworm (Bombyx mori L.) using two-dimensional polyacrylamide gel electrophoresis. Yuan-Xiang Jin Yu-Yin Chen Meng-Kui Xu Yong-Huang Jiang. Articles Volume 29 Issue 1 March 2004 pp 45- ...

  1. Cichorium intybus L

    African Journals Online (AJOL)

    DR TONUKARI NYEROVWO

    2011-03-14

    Mar 14, 2011 ... production (Baumhardt et al., 2009; Po et al., 2009), ... therefor, it can be use as both health care food and ... 2009),effects of the biological activities (Jiang et al., ...... 210. URL: http://acad.cnki.net/kns55/detail/detail.aspx?

  2. 78 FR 36820 - Notice of Application for Special Permits

    Science.gov (United States)

    2013-06-19

    ... aircraft, in remote areas of the US only, without being subject to hazard communication requirements... acid in non-DOT specification one-time use HDPE plastic drums. (mode 1) 15873-N JiangXi Oxygen Plant 49... aircraft, in remote areas of the US only, without being subject to hazard communication requirements...

  3. Short communication Validation of the 50k Illumina goat SNP chip in ...

    African Journals Online (AJOL)

    Simon

    2015-03-12

    Mar 12, 2015 ... Genet. App. Livest. Prod. Vancouver, BC, Canada, 2014. Poster presentation, 882. Davis, N.A., Pandey, A. & McKinney, B.A., 2011. Real-world comparison of CPU and GPU implementations of SNPrank: a network analysis tool for GWAS. Bioinformatics 27, 284-285. Dong, Y., Xie, M., Jiang, Y., Xiao, N., Du, ...

  4. Comparison of response formats and concurrent hedonic measures for optimal use of the EmoSensory® Wheel

    DEFF Research Database (Denmark)

    Schouteten, Joachim J.; Gellynck, Xavier; De Bourdeaudhuij, Ilse

    2017-01-01

    The study of emotional and sensory profiling with food products is gaining momentum in the field of sensory research. These methods can be applied in order to obtain a broader consumer perspective on product performance beyond traditional hedonic measurements (Jiang, King, & Prinyawiwatkul, 2014;...

  5. Colloquium: Quantum Networks with Trapped Ions

    Science.gov (United States)

    2010-04-28

    observed be- tween two ions held in the same trap Eichmann et al., 1993; DeVoe and Brewer, 1996. Type-II links have the advantage of being less sensitive...Childress, E. Jiang, J. Togan, J. Maze, F. Jelezko, A. S. Zibrov, P. R. Hemmer, and M. D. Lukin, 2007, Science 316, 1312. Eichmann , U., J. C. Bergquist

  6. Nanomechanics of materials and structures

    National Research Council Canada - National Science Library

    Chuang, T.-J

    2006-01-01

    ... On the Tensile Strength of a Solid Nanowire Tze-jer Chuang ······························· 67 Fracture Nucleation in Single-Wall Carbon Nanotubes H. Jiang, Y. Huang , P...

  7. Bacterial Genome Engineering and Synthetic Biology: Combating Pathogens

    Science.gov (United States)

    2016-11-04

    extremely high genome sequence similarity between non-pathogenic and pathogenic strains by targeting small sequence variations present in the...Microbiol 2011, 14(5):524-531. 46. Bikard D, Euler CW, Jiang W, Nussenzweig PM, Goldberg GW, Duportet X, Fischetti VA, Marraffini LA: Exploiting

  8. In situ Raman Spectroscopy Study of the Formation of Graphene from Urea and Graphite Oxide

    Science.gov (United States)

    2012-09-01

    pp. 075404, Aug., 2006. [5] K. S. Novoselov, Z. Jiang, Y. Zhang, S. Morozov, H. Stormer , U. Zeitler, J. Maan, G. Boebinger, P. Kim, and A. Geim...Room-temperature quantum hall effect in graphene.” Science, vol. 315, no. 5817, pp. 1379, Mar., 2007. [6] Y. Zhang, Y. W. Tan, H. L. Stormer , and

  9. Electron Transport in Graphene From a Diffusion-Drift Perspective

    Science.gov (United States)

    2010-02-24

    Tung, M.E. Schwartz, M. Takita, Y.-J. Wang, P. Kim, and H.L. Stormer , “Cyclotron resonance in bilayer graphene,” Phys. Rev. Lett. 100, 087403 (2008...Dec. 2004. [3] K. I. Bolotin, K. J. Sikes, Z. Jiang, M. Klima, G. Fudenberg, J. Hone, P. Kim, and H. L. Stormer , “Ultrahigh electron mobility in

  10. Neural Control of Rising and Falling Tones in Mandarin Speakers Who Stutter

    Science.gov (United States)

    Howell, Peter; Jiang, Jing; Peng, Danling; Lu, Chunming

    2012-01-01

    Neural control of rising and falling tones in Mandarin people who stutter (PWS) was examined by comparing with that which occurs in fluent speakers [Howell, Jiang, Peng, and Lu (2012). Neural control of fundamental frequency rise and fall in Mandarin tones. "Brain and Language, 121"(1), 35-46]. Nine PWS and nine controls were scanned. Functional…

  11. A novel missense mutation in collagenous domain of EDA gene in a ...

    Indian Academy of Sciences (India)

    Supplementary data: A novel missense mutation in collagenous domain of EDA gene in a. Chinese family with X-linked hypohidrotic ectodermal dysplasia. Daxu Li, Ran Xu, Fumeng Huang, Biyuan Wang, Yu Tao, Zijian Jiang, Hairui Li, Jianfeng Yao,. Peng Xu, Xiaokang Wu, Le Ren, Rui Zhang, John R. Kelsoe and Jie Ma.

  12. Journal of Earth System Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science. Ju Wei. Articles written in Journal of Earth System Science. Volume 125 Issue 5 July 2016 pp 1021-1031. Tectonic stress accumulation in Bohai–Zhangjiakou Seismotectonic Zone based on 3D visco-elastic modelling · Ju Wei Sun Weifeng Ma Xiaojing Jiang Hui.

  13. Cloning, chromosome localization and features of a novel human ...

    Indian Academy of Sciences (India)

    Unknown

    Math2 may have the same functions in the nervous system. [Guo L., Jiang M., Ma Y., Cheng ... from a human foetal brain cDNA library, and its localiza- tion in the human ... using the BLASTN,. BLASTP and BLASTX algorithms on the NCBI web.

  14. China's Policymaking for Regional Economic Cooperation

    DEFF Research Database (Denmark)

    Jiang, Yang

    Yang Jiang opens the black box of China's policymaking for free trade agreements and key regional financial initiatives. Using first-hand interview data, she sheds light on the key trends of China's trade and financial politics after its WTO entry in 2001. In particular, she highlights...

  15. Download this PDF file

    African Journals Online (AJOL)

    Dan Jiang 1*, Jian-Hong Zhou 2*, Jue Zhou 3 , Ying-Er Gu 2, Dong-Xia Yang 4, Qing .... Women were informed about the short- and long-term benefits of HRT. .... Current employment status .... randomized, double-blind, controlled trial of a Chinese herbal formula (Er-Xian decoction) for menopausal symptoms in Hong Kong.

  16. Response of Oncomelania snail distribution on land use in Sichuan ...

    African Journals Online (AJOL)

    Response of Oncomelania snail distribution on land use in Sichuan, China. Q Sun, Z Peng, J Zhang, J Jiang. Abstract. Schistosomiasis is one of the four major infectious diseases that require prevention and control in China. It is mainly distributed along the middle and downstream areas of the Yangtze River and some hilly ...

  17. Morphological evolution in single-crystalline Bi2Te3 nanoparticles ...

    Indian Academy of Sciences (India)

    to have ZT exceeding 5 (Lin et al 2000). ... as nanoparticles (NPs) (Jiang and Zhu 2007; Cao et al. 2008a, b) ... als, semimetals, alloys and other compounds (Chen and ..... Cao Y Q, Zhao X B, Zhu T J, Zhang X B and Tu J P 2008a Appl. Phys.

  18. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. Lingchen Guo. Articles written in Journal of Genetics. Volume 81 Issue 1 April 2002 pp 13-17 Perspectives. Cloning, chromosome localization and features of a novel human gene, MATH2 · Lingchen Guo Min Jiang Yushu Ma Haipeng Cheng Xiaohua Ni Yangsheng Jin Yi Xie Yumin ...

  19. Micro-Photoluminescence (micro-PL) Study of Core-Shell GaAs/GaAsSb Nanowires Grown by Self-Assisted Molecular Beam Epitaxy

    Science.gov (United States)

    2015-06-18

    U.S. Army Research Office P.O. Box 12211 Research Triangle Park, NC 27709-2211 GaAsSb, Core Shell Nanowires, Micro Photoluminescence...34 Nanotechnology , vol. 24, no. 40 , 2013 . [6] H. Joyce, P. Parkinson , N. Jiang, C. Docherty, Q. Gao, H. Tan, C. Jagadish, L. Herz and M. Johnston

  20. Disease: H01553 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H01553 Zika fever; Zika virus disease Zika fever is one of the mosquito-borne viral fevers caused by Zika...n to human through bites of Aedes species. ZIKV was initially distinguished in rhesus monkeys in the Zika fo...etween microcephaly and of Zika virus. It has been reported that ZIKV-infected children, who were born to ZI...nces below the 10th percentile. Infectious disease ... Zika virus [GN:T40049] ... Serodiagnosis by IgM ELISA test... AUTHORS ... Maharajan MK, Ranjan A, Chu JF, Foo WL, Chai ZX, Lau EY, Ye HM, Theam

  1. Main: 1FWO [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1FWO イネ Rice Oryza sativa L. Oryzain Beta Chain Precursor Oryza Sativa Molecule: Oryzain Beta Chain; Chai...eered: Yes; Mutation: Yes Hydrolase 3.4.22.- (Oryzain Beta Chain) D.Tolkatchev, P.Xu, F.Ni D.Tolkatchev, P.X...olds Into A Stack Of Two Beta-Hairpins, A Scaffold Present In The Emerging Family Of Granulin-Like Growth Fa...ctors J.Pept.Res. V. 57 227 2001 Beta-Hairpin Stack Fold, Granulin/Epithelin-Like Protein Repeats SWS:ORYB_O

  2. Néron Models and Base Change

    DEFF Research Database (Denmark)

    Halle, Lars Halvard; Nicaise, Johannes

    Presenting the first systematic treatment of the behavior of Néron models under ramified base change, this book can be read as an introduction to various subtle invariants and constructions related to Néron models of semi-abelian varieties, motivated by concrete research problems and complemented...... on Néron component groups, Edixhoven’s filtration and the base change conductor of Chai and Yu, and we study these invariants using various techniques such as models of curves, sheaves on Grothendieck sites and non-archimedean uniformization. We then apply our results to the study of motivic zeta functions...

  3. Biofilms and Persistent Wound Infections in United States Military Trauma Patients: a Case-control Analysis

    Science.gov (United States)

    2014-04-08

    Infect Dis. 2014, 21:21-23. 51. Hochbaum AI, Kolodkin-Gal I, Foulston L, Kolter R, Aizenberg J, Losick R: Inhibitory effects of D-amino acids on...Staphylococcus aureus biofilm development. J Bacteriol 2011, 193(20):5616–5622. 52. Kolodkin-Gal I, Romero D, Cao S, Clardy J, Kolter R, Losick R: D-amino...acids trigger biofilm dissambly. Science 2010, 328(5978):627–629. 53. Kolodkin-Gal I, Cao S, Chai L, Bottcher T, Kolter R, Clardy J, Losick R: A self

  4. A Battlefield Obscuration Model (Smoke & Dust)

    Science.gov (United States)

    1979-10-01

    ia £ utace of clouds, izsclacioon (incoming radiation) during :he day ts dependent upon solar ali.::ude, which is a fuc nof time of: d&7 and time of...year. ’Irnn clouds exisc, chai~r cover and :b*ickness decrease incoming and ouzgoingS radiation. Z-a this syscea iasola:ion ts estimated b7 solar ...alzictude and =odi44ed -or existing condi:±ons of total cloud cover and cloud ceiling height. kc zig~ic, estimates of oucgoing radiacion are =ade by

  5. ORF Alignment: NC_002655 [GENIUS II[Archive

    Lifescience Database Archive (English)

    Full Text Available mational Changes In ... A Protease- Associated Atpase Hslu pdb|1HQY|C Chai...n C, ... Nucleotide-Dependent Conformational Changes In A ... Protease- Associated Atpase Hslu... pdb|1HQY|B Chain B, ... Nucleotide-Dependent Conformational Changes In A ... Protease- Associated Atpase...al Changes In A ... Protease- Associated Atpase Hslu pdb|1HT1|Y Chain Y, ... Nucleotide-Depend...ent Conformational Changes In A ... Protease- Associated Atpase Hslu pdb|1HT1|Z Chain Z, ... N

  6. ORF Alignment: NC_004431 [GENIUS II[Archive

    Lifescience Database Archive (English)

    Full Text Available mational Changes In ... A Protease- Associated Atpase Hslu pdb|1HQY|C Chai...n C, ... Nucleotide-Dependent Conformational Changes In A ... Protease- Associated Atpase Hslu... pdb|1HQY|B Chain B, ... Nucleotide-Dependent Conformational Changes In A ... Protease- Associated Atpase...al Changes In A ... Protease- Associated Atpase Hslu pdb|1HT1|Y Chain Y, ... Nucleotide-Depend...ent Conformational Changes In A ... Protease- Associated Atpase Hslu pdb|1HT1|Z Chain Z, ... N

  7. ORF Alignment: NC_000913 [GENIUS II[Archive

    Lifescience Database Archive (English)

    Full Text Available mational Changes In ... A Protease- Associated Atpase Hslu pdb|1HQY|C Chai...n C, ... Nucleotide-Dependent Conformational Changes In A ... Protease- Associated Atpase Hslu... pdb|1HQY|B Chain B, ... Nucleotide-Dependent Conformational Changes In A ... Protease- Associated Atpase...al Changes In A ... Protease- Associated Atpase Hslu pdb|1HT1|Y Chain Y, ... Nucleotide-Depend...ent Conformational Changes In A ... Protease- Associated Atpase Hslu pdb|1HT1|Z Chain Z, ... N

  8. ORF Alignment: NC_002695 [GENIUS II[Archive

    Lifescience Database Archive (English)

    Full Text Available mational Changes In ... A Protease- Associated Atpase Hslu pdb|1HQY|C Chai...n C, ... Nucleotide-Dependent Conformational Changes In A ... Protease- Associated Atpase Hslu... pdb|1HQY|B Chain B, ... Nucleotide-Dependent Conformational Changes In A ... Protease- Associated Atpase...al Changes In A ... Protease- Associated Atpase Hslu pdb|1HT1|Y Chain Y, ... Nucleotide-Depend...ent Conformational Changes In A ... Protease- Associated Atpase Hslu pdb|1HT1|Z Chain Z, ... N

  9. ORF Alignment: NC_004337 [GENIUS II[Archive

    Lifescience Database Archive (English)

    Full Text Available mational Changes In ... A Protease- Associated Atpase Hslu pdb|1HQY|C Chai...n C, ... Nucleotide-Dependent Conformational Changes In A ... Protease- Associated Atpase Hslu... pdb|1HQY|B Chain B, ... Nucleotide-Dependent Conformational Changes In A ... Protease- Associated Atpase...al Changes In A ... Protease- Associated Atpase Hslu pdb|1HT1|Y Chain Y, ... Nucleotide-Depend...ent Conformational Changes In A ... Protease- Associated Atpase Hslu pdb|1HT1|Z Chain Z, ... N

  10. Temporal Differential Gene Expression in Explanted Human Retinal Pigment Epithelial Cells at 0.5, 1.0, 3.0, 6.0, 12 and 24 Hours Post-Exposure to 1064 nm, 3.6 ns Pulsed Laser Light

    Science.gov (United States)

    2005-05-01

    regulated 10-fold at 1-3 hrs and -5-fold at 12 hrs. Roughly the same can be said for xeroderma pigmentosum group CC repair complementing protein p58 (C08n...Staudt L M, Hudson J, Boguski MS, Lashkari D, Shalon D, Botstein D and Brown PO : The Transcriptional Program in the Response of Human Fibroblasts to...467-470. Schena M, Shalon D, Heller R, Chai A, Brown PO , Davis R: Parallel human genome analysis: Microarray-based expression monitoring of 1000 genes

  11. Calculations in fundamental physics mechanics and heat

    CERN Document Server

    Heddle, T

    2013-01-01

    Calculations in Fundamental Physics, Volume I: Mechanics and Heat focuses on the mechanisms of heat. The manuscript first discusses motion, including parabolic, angular, and rectilinear motions, relative velocity, acceleration of gravity, and non-uniform acceleration. The book then discusses combinations of forces, such as polygons and resolution, friction, center of gravity, shearing force, and bending moment. The text looks at force and acceleration, energy and power, and machines. Considerations include momentum, horizontal or vertical motion, work and energy, pulley systems, gears and chai

  12. Browse Author Index

    African Journals Online (AJOL)

    A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All. C. Chai, Furaha · Charwi, Mary Z. Chiduo, E.K.F 1 - 3 of 3 Items. ISSN: 0856-552X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact ...

  13. The effect of problems on supply chain wide efficiency

    OpenAIRE

    Micheline J. Naude; Johanna A. Badenhorst-Weiss

    2011-01-01

    For any business to compete successfully in the modern, globalised business environment, it needs to mobilise its suppliers and customers to co-operate in order to reduce unnecessary costs and inefficiencies between them and to ensure the best value for the final customer. The focus is on management of the supply chain as a whole (or a system) and maximum value for the final customer of the supply chain, instead of on management for the maximum benefit of one of the parties in the supply chai...

  14. Upregulation of metastasis-associated gene 2 promotes cell proliferation and invasion in nasopharyngeal carcinoma

    Directory of Open Access Journals (Sweden)

    Wu MH

    2016-03-01

    Full Text Available Minhua Wu,1,2,* Xiaoxia Ye,2,* Xubin Deng,3,* Yanxia Wu,4 Xiaofang Li,4 Lin Zhang11Department of Histology and Embryology, Southern Medical University, Guangzhou, 2Department of Histology and Embryology, Guangdong Medical University, Zhanjiang, 3Affiliated Cancer Hospital of Guangzhou Medical University, Cancer Center of Guangzhou Medical University, Guangzhou, 4Pathological Diagnosis and Research Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, People’s Republic of China*These authors contributed equally to this workAims: Metastasis-associated gene 2 (MTA2 is reported to play an important role in tumor progression, but little is known about the role of MTA2 in nasopharyngeal carcinoma (NPC. The aim of the study was to explore the expression and function of MTA2 in NPC.Methods: Expression of MTA2 in NPC tissues and cell lines was detected by immunohistochemistry and Western blotting. Relationship between MTA2 expression and clinicopathological features was analyzed. Stable MTA2-overexpressing and MTA2-siliencing NPC cells were established by transfection with plasmids encoding MTA2 cDNA and lentivirus-mediated short hairpin RNA, respectively. Cell viability was determined by Cell Counting Kit-8 and colony formation assay. Cell migration ability was evaluated by wound healing and transwell invasion assay. The impact of MTA2 knockdown on growth and metastasis of CNE2 cells in vivo was determined by nude mouse xenograft models. Expression of several Akt pathway proteins was detected by Western blotting.Results: MTA2 was upregulated in NPC tissues and three NPC cell lines detected (CNE1, CNE2, and HNE1. MTA2 expression was related to clinical stage and lymph node metastasis of patients with NPC. MTA2 upregulation promoted proliferation and invasion of CNE1 cells, while MTA2 depletion had opposite effects on CNE2 cells. Moreover, MTA2 depletion suppressed growth and metastasis of CNE2 cells in vivo. MTA2 overexpression

  15. Patterns of persistence with pharmacological treatment among patients with current depressive episode and their impact on long-term outcome: a naturalistic study with 5-year follow-up

    Directory of Open Access Journals (Sweden)

    Li K

    2018-05-01

    Full Text Available Kanglai Li,1,* Jiong Tao,2,* Yuemei Li,3 Minhua Chen,2 Xiuhua Wu,2 Yingtao Liao,2 Xiaolan Lin,4 Zhaoyu Gan2 1Department of Very Important Patient, the 3rd Affiliated Hospital of Sun Yat-sen University, Guangzhou, People’s Republic of China; 2Department of Psychiatry, the 3rd Affiliated Hospital of Sun Yat-sen University, Guangzhou, People’s Republic of China; 3Department of Obstetrics, Wuzhou Gongren Hospital, Wuzhou, People’s Republic of China; 4Department of Infectious Diseases, the 3rd Affiliated Hospital of Sun Yat-Sen University, Guangzhou, People’s Republic of China *These authors contributed equally to this work Background: The aim of the study was to describe and compare the patterns of medication persistence among patients with unipolar depression (UD or bipolar depression in a 5-year follow-up, and explore their impact on long-term outcome. Patients and methods: A total of 333 eligible patients with current major depressive episode were observed and followed up from the first index prescription for 5 years. Lack of persistence or treatment interruption was defined as a gap of at least 2 consecutive months without taking any medication. Time to lack of persistence in the first (TLP1 and the second (TLP2 episode of treatment, number of visits before the first treatment interruption (NV and number of treatment interruptions (NTI were measured. Results: During the 5-year follow-up, nearly 50% of patients experienced at least two times of treatment interruption. Pattern of medication persistence did not significantly differ between UD and bipolar disorder (BD patients. TLP1 was positively associated with TLP2. Shorter TLP1 predicted a higher possibility of subsequent visits because of recurrence or relapse and more NTI meant a lower likelihood of achieving full remission in the fifth year for both UD and BD patients. For UD patients, shorter TLP1 or less NV predicted a lower chance of achieving remission, while for BD patients

  16. Construction of a Composite Hospital Admission Index Using the Aggregated Weights of Criteria

    International Nuclear Information System (INIS)

    Nor Hasliza Mat Desa; Abdul Aziz Jemain; Maznah Mat Kasim

    2015-01-01

    The issue of age difference in hospital admission should be given special attention since it affects the structure of hospital care and treatments. Patients of different age groups should be given different priority in service provision. Due to crucial time and limited resources, health care managers need to make wise decisions in identifying priorities in age of admission. This paper aimed to propose a construction of a daily composite hospital admission index (CHAI) as an indicator that captures relevant information about the overall performance of hospital admission over time. It involves five different age groups of total patients admitted to seven major public hospitals in the Klang Valley, Malaysia for respiratory and cardiovascular diseases for a period of three years, 2008 - 2010. The criteria weights were predetermined by aggregating the subjective weight based on rank ordered centroid (ROC) method and objective weight based on entropy - kernel method. The highest and lowest scores of CHAI were marked, while the groups of patients were prioritized according to the criteria weight ranking orders. (author)

  17. Les présidents chinois et suisse visitent le CERN

    CERN Multimedia

    CERN Press Office. Geneva

    1999-01-01

    Le vendredi 26 mars 1999, Jiang Zemin, Président de la République populaire de Chine, et Ruth Dreifuss, Présidente de la Confédération suisse, ont visité le Laboratoire européen pour la physique des particules, le CERN . Ils ont été accueillis par le Directeur général, Luciano Maiani, sur les lieux de l'expérience L3. En 1985, Jiang Zemin, alors maire de Shanghai, avait contribué à organiser la production de cristaux de BGO à l'Institut de céramique de Shanghai, cristaux qui jouent aujourd'hui un rôle essentiel dans l'expérience L3

  18. Publisher Correction: A Co3O4-CDots-C3N4 three component electrocatalyst design concept for efficient and tunable CO2 reduction to syngas.

    Science.gov (United States)

    Guo, Sijie; Zhao, Siqi; Wu, Xiuqin; Li, Hao; Zhou, Yunjie; Zhu, Cheng; Yang, Nianjun; Jiang, Xin; Gao, Jin; Bai, Liang; Liu, Yang; Lifshitz, Yeshayahu; Lee, Shuit-Tong; Kang, Zhenhui

    2018-02-08

    The original HTML version of this Article omitted to list Yeshayahu Lifshitz as a corresponding author and incorrectly listed Shuit-Tong Lee as a corresponding author.Correspondingly, the original PDF version of this Article incorrectly stated that "Correspondence and requests for materials should be addressed to X.J. (email: xin.jiang@uni-siegen.de), or to Y.L. (email: yangl@suda.edu.cn), or to S.-T.L. (email: shayli@technion.ac.il), or to Z.K. (email: zhkang@suda.edu.cn)", instead of the correct "Correspondence and requests for materials should be addressed to X.J. (email: xin.jiang@uni-siegen.de), or to Y. Liu (email: yangl@suda.edu.cn), or to Y. Lifshitz (email: shayli@technion.ac.il), or to Z.K. (email: zhkang@suda.edu.cn)".This has now been corrected in the PDF and HTML versions of the Article.

  19. Calibration of Chaboche Model with a Memory Surface

    Directory of Open Access Journals (Sweden)

    Radim HALAMA

    2013-06-01

    Full Text Available This paper points out a sufficient description of the stress-strain behaviour of the Chaboche nonlinear kinematic hardening model only for materials with the Masing's behaviour, regardless of the number of backstress parts. Subsequently, there are presented two concepts of most widely used memory surfaces: Jiang-Sehitoglu concept (deviatoric plane and Chaboche concept (strain-space. On the base of experimental data of steel ST52 is then shown the possibility of capturing hysteresis loops and cyclic strain curve simultaneously in the usual range for low cycle fatigue calculations. A new model for cyclic hardening/softening behaviour modeling has been also developed based on the Jiang-Sehitoglu memory surface concept. Finally, there are formulated some recommendations for the use of individual models and the direction of further research in conclusions.

  20. 奥运短讯

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Olympic Games FounderRemembered A seminar to mark the birthday ofPierre de Coubertin,founder of themodern Olympic Games,was held inBeijing on January 1.Jiang Xiaoyu,vice president of theBeijing Olympic Games OrganizingCommittee,senior IOC member HeZhenliang and Olympic historian SunBaoli delivered speeches in memory ofMr.Coubertin who Was born OnJanuary 1,1863.

  1. Purification and in vitro antioxidant activities of tellurium-containing phycobiliproteins from tellurium-enriched Spirulina platensis

    OpenAIRE

    Chen, Tianfeng; Yang,Fang; Wong,Ka-Hing; Yang,Yufeng; Li,Xiaoling; Jiang,Jie; Wu,Hualian; Zheng,Wenjie

    2014-01-01

    Fang Yang,1 Ka-Hing Wong,2 Yufeng Yang,3 Xiaoling Li,1 Jie Jiang,1 Wenjie Zheng,1 Hualian Wu,1 Tianfeng Chen1 1Department of Chemistry, Jinan University, Guangzhou, People’s Republic of China; 2Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, People’s Republic of China; 3Institute of Hydrobiology, College of Life Science and Technology, Jinan University, Guangzhou, People’s Republic of China Abstract: Tellu...

  2. Distributed Cooperative Control of Multiple Nonlinear Systems with Nonholonomic Constraints and Uncertainty

    Science.gov (United States)

    2015-04-04

    this testbed, there are four P3-AT mobile robots. Each robot is equipped with a camera and a laser sensor. Between robots, there is wireless...shows the formation tracking of the 4 followers, the blue spots represent each follower robot, the black spot represent the trajectory of centroid of...P. Jiang, “Lyapunov design of global state and output trackers for nonholonomic control systems,” Int. J. of Control, pp. 744–761, 2000. [97] Y. P

  3. TWSTFT Data Treatment for UTC Time Transfer

    Science.gov (United States)

    2009-11-01

    BUREAU INTERNATIONAL DES POIDS ET MESURES ORGANISATION INTERGOUVERNEMENTALE DE LA CONVENTION DU METRE...in [UTC-UTC(k)],” Metrologia , 43, 278-286. [4] BIPM Circular T 244, Section 6, May 2008, http://www.bipm.org [5] D. Piester, A. Bauch, L... Metrologia , 45, 185-198. [6] F. Arias, Z. Jiang, G. Petit, and W. Lewandowski, 2005, “BIPM Comparison of Time Transfer Techniques,” in Proceedings

  4. English-Chinese Cross-Language IR Using Bilingual Dictionaries

    Science.gov (United States)

    2006-01-01

    specialized dictionaries together contain about two million entries [6]. 4 Monolingual Experiment The Chinese documents and the Chinese translations of... monolingual performance. The main performance-limiting factor is the limited coverage of the dictionary used in query translation. Some of the key con...English-Chinese Cross-Language IR using Bilingual Dictionaries Aitao Chen , Hailing Jiang , and Fredric Gey School of Information Management

  5. H CHEN

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. H CHEN. Articles written in Bulletin of Materials Science. Volume 41 Issue 2 April 2018 pp 51. Effect of oxygen vacancies on Li-storage of anatase TiO 2 (001) facets: a first principles study · H CHEN Y H DING X Q TANG W ZHANG J R YIN P ZHANG Y JIANG · More Details ...

  6. Y H DING

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Y H DING. Articles written in Bulletin of Materials Science. Volume 41 Issue 2 April 2018 pp 51. Effect of oxygen vacancies on Li-storage of anatase TiO 2 (001) facets: a first principles study · H CHEN Y H DING X Q TANG W ZHANG J R YIN P ZHANG Y JIANG · More Details ...

  7. w zhang

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. W ZHANG. Articles written in Bulletin of Materials Science. Volume 41 Issue 2 April 2018 pp 51. Effect of oxygen vacancies on Li-storage of anatase TiO 2 (001) facets: a first principles study · H CHEN Y H DING X Q TANG W ZHANG J R YIN P ZHANG Y JIANG · More Details ...

  8. p zhang

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. P ZHANG. Articles written in Bulletin of Materials Science. Volume 41 Issue 2 April 2018 pp 51. Effect of oxygen vacancies on Li-storage of anatase TiO 2 (001) facets: a first principles study · H CHEN Y H DING X Q TANG W ZHANG J R YIN P ZHANG Y JIANG · More Details ...

  9. X Q TANG

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. X Q TANG. Articles written in Bulletin of Materials Science. Volume 41 Issue 2 April 2018 pp 51. Effect of oxygen vacancies on Li-storage of anatase TiO 2 (001) facets: a first principles study · H CHEN Y H DING X Q TANG W ZHANG J R YIN P ZHANG Y JIANG · More Details ...

  10. Optimal Mass Transport for Statistical Estimation, Image Analysis, Information Geometry, and Control

    Science.gov (United States)

    2017-01-10

    advances on formulating and solving optimal transport problems on discrete spaces (networks) while ensuring robustness of the transportation plan. This...Metric Uncertainty for Spectral Estimation based on Nevanlinna-Pick Interpolation, (with J. Karlsson) Intern. Symp. on the Math . Theory of Networks and...Systems, Melbourne 2012. 22. Geometric tools for the estimation of structured covariances, (with L. Ning, X. Jiang) Intern. Symposium on the Math . Theory

  11. Magnetic resonance-guided regional gene delivery strategy using a tumor stroma-permeable nanocarrier for pancreatic cancer

    OpenAIRE

    Wang, Xiaolin; Wang,Qingbing; Li,Jianfeng; An,Sai; Chen,Yi; Jiang,Chen

    2015-01-01

    Qingbing Wang,1,2 Jianfeng Li,3 Sai An,3 Yi Chen,1 Chen Jiang,3 Xiaolin Wang1,2 1Department of Interventional Radiology, Zhongshan Hospital, Fudan University, 2Shanghai Institute of Medical Imaging, 3Key Laboratory of Smart Drug Delivery, Ministry of Education, Department of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, People’s Republic of China Background: Gene therapy is a very promising technology for treatment of pancreatic ductal adenocarci...

  12. Browse Title Index

    African Journals Online (AJOL)

    Items 51 - 100 of 1309 ... Li-Long Liu, Kai Xu, Lu-Mei Kang, Shu-Ping Jiang, Qing-Hua Wang, ... CR Sewani-Rusike, JE Iputo, EJ Ndebia, M Gondwe, DR Kamadyaapa ... K-M Man, W-C Chen, H-M Wang, H-Y Chen, J-L Shen, L-D Chen, F-J Tsai, ...

  13. Orbit Estimation of Non-Cooperative Maneuvering Spacecraft

    Science.gov (United States)

    2015-06-01

    using calculus of variations [145:1-43]. For several of the topics reviewed, there are specific works that use optimization routines in coordination...Jiang et al. and Han et al. use the approach of optimizing a cost function with gradients to adaptively change the process noise covariance [69; 146...forward network with sigmoid and output neurons is used to classify cases. The network is trained using the scaled conjugate gradient back propagation

  14. A homotopy method based on WENO schemes for solving steady state problems of hyperbolic conservation laws

    Science.gov (United States)

    2012-09-03

    27] introduced a new smoothness indicator, which removed the slight post- shock oscillations and improved the convergence . A Newton- iteration method... Gauss - Seidel algorithm for steady Euler equation on unstructured grids, Numer. Math. Theor. Meth. Appl., Vol. 1, pp. 92–112, (2008). [14] G.-S. Jiang...was adopted to solve the steady two dimensional Euler equations [10, 11, 13]. The matrix-free Squared Preconditioning is applied to a Newton iteration

  15. Global temperature estimates in the troposphere and stratosphere: a validation study of COSMIC/FORMOSAT-3 measurements

    CSIR Research Space (South Africa)

    Kishore, P

    2009-02-04

    Full Text Available and Communications Technology, Tokyo, Japan 3Jet Propulsion Laboratory, Pasadena, CA, USA 4National Laser Centre, CSIR, Pretoria, South Africa 5Department of Geography, Geoinformatics and Meteorology, University of Pretoria, South Africa Received: 13 November... and Communications Technology (NICT), for their financial support. J. H. Jiang thanks the support by Microwave Atmospheric Science Team at Jet Propulsion Laboratory, California Institute of Technology, under contract with NASA. Edited by: W. Conant References...

  16. Modulation of PPAR-Gamma Signaling in Prostatic Carcinogenesis

    Science.gov (United States)

    2009-09-01

    more prominent nucleoli , compatible with lesions previously categorized as mouse prostatic intraepithelial neoplasia (PIN) I in genetically engineered...differentiation. Nuclear enlargement with chromatin clumping and prominent nucleoli was noted (Figure 1). No foci of invasive carcinoma were identified in...of PPARc results in autophagy and mPIN M Jiang et al 6 Cell Death and Differentiation abnormal features. There were enlarged nuclei with large nucleoli

  17. Contextual cueing based on the semantic-category membership of the environment

    OpenAIRE

    GOUJON, A

    2005-01-01

    During the analysis of a visual scene, top-down processing is constantly directing the subject's attention to the zones of interest in the scene. The contextual cueing paradigm developed by Chun and Jiang (1998) shows how contextual regularities can facilitate the search for a particular element via implicit learning mechanisms. In the proposed study, contextual cueing task with lexical displays was used. The semantic-category membership of the contextual words predicted the location of the t...

  18. Two (or three) is one too many : testing the flexibility of contextual cueing with multiple target locations

    OpenAIRE

    Zellin, Martina; Conci, Markus; von Mühlenen, Adrian; Müller, Hermann J.

    2011-01-01

    Visual search for a target object is facilitated when the object is repeatedly presented within an invariant context of surrounding items ("contextual cueing"; Chun & Jiang, Cognitive Psychology, 36, 28-71, 1998). The present study investigated whether such invariant contexts can cue more than one target location. In a series of three experiments, we showed that contextual cueing is significantly reduced when invariant contexts are paired with two rather than one possible target location, whe...

  19. Contextual cueing based on specific and categorical properties of the environment

    OpenAIRE

    Goujon , A.; Didierjean , A.; Marmeche , E.

    2007-01-01

    During the analysis of a visual scene, top-down processing is constantly directing the subject's attention to the zones of interest in the scene. The contextual cueing paradigm developed by Chun and Jiang (1998) shows how contextual regularities can facilitate the search for a particular element via implicit learning mechanisms. The study presented here reports three experiments that used this paradigm. Experiment 1 showed that regularities in the specific elements of the context can act as c...

  20. Passive Mode Carbon Nanotube Underwater Acoustic Transducer

    Science.gov (United States)

    2016-09-20

    Acoustical transducer arrays can reflect a sound signal in reverse to the sender which can be used for echo location devices. [0008] In Jiang...States Patent No. 8,494,187) a sound wave generator is disclosed which includes a carbon nanotube structure and an insulating reinforcement structure... acoustic device that includes an electrode layer and a sound wave generator. The sound wave generator is disposed on a surface of the electrode

  1. Short Communication

    African Journals Online (AJOL)

    huis

    Short Communication. QTL analysis of production traits on SSC3 in a Large White×Meishan pig resource family. B. Zuo. 1. , Y.Z. Xiong. 1#. , Y.H. Su. 2. , C.Y. Deng. 1. , M.G. Lei. 1. , F.E. Li. 1. , R. Zheng. 1 and S.W. Jiang. 1. 1 Key Laboratory of Swine Genetics and Breeding, Ministry of Agriculture & Key Lab of Agricultural ...

  2. Multiscale Mathematics for Nano-Particle-Endowed Active Membranes and Films

    Science.gov (United States)

    2016-08-03

    graduated and move on to either continue their postdoc training or working in universities and industries . The team has been very productive during...6402. 21. Hua Jiang, Hao Yang, Jun Zeng, Zhiyuan Zhou, Jin Peng, Qi Wang, Analytic Oncology, Electron J Metab Nutr Cancer,Jun. 2015,Vol. 2, No. 2, 26...approved for public release. 6 Hill, July 2016-present 2. Norazaliza Mond Gamil, PhD May 2015, Universiti Malaysia Pahang, 2015- present 3. Chen

  3. Given the Absence of Established Doctrine, are there Concepts and Doctrinal Guidance Available from Varying Sources, Which are Relevant to Shaping the Capabilities of the Jamaica Defence Force to Achieve its Mission in the 21st Century

    Science.gov (United States)

    2010-12-10

    the ruling People’s National Party (PNP) and Fidel Castro, communist leader of Cuba . The opposition party at the time was the Jamaica Labour Party...Sea. It is approximately, 145 kilometers (90 miles) south of Cuba . Its coastline extends for 1,022 kilometers (634 miles). Jamaica practices a...Qin, Chairman Mao Tse-tung, Deng Xiaoping and Jiang Zemin. The foundation principles of Marxism are revered and built upon by the respective military

  4. Facile synthesis of new thermally stable and organosoluble ...

    Indian Academy of Sciences (India)

    Hamciuc E, Hamciuc C and Bruma M 2007 Eur. Polym. J. 43 4739. 31. Sponton M, Mercado L A, Ronda J C, Galia M and. Cadiz V 2008 Polym. Degrad. Stabil. 93 2025. 32. Zhang W, Li X, Jiang Y and Yang R 2013 Polym. Degrad. Stabil. 98 246. 33. Ren H, Sun J, Wu B and Zhou Q 2007 Polym. Degrad. Stabil. 92 956. 34.

  5. Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia?reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice

    OpenAIRE

    Feng, Jiao; Zhang, Qinghui; Mo, Wenhui; Wu, Liwei; Li, Sainan; Li, Jingjing; Liu, Tong; Xu, Shizan; Fan, Xiaoming; Guo, Chuanyong

    2017-01-01

    Jiao Feng,1,* Qinghui Zhang,2,* Wenhui Mo,3,* Liwei Wu,1 Sainan Li,1 Jingjing Li,1 Tong Liu,1 Shizan Xu,4 Xiaoming Fan,5 Chuanyong Guo1 1Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 2Department of Clinical Laboratory, Kunshan First People’s Hospital Affiliated to Jiangsu University, Kunshan, JiangSu, 3Department of Gastroenterology, Minhang Hospital, Fudan University, Shanghai, 4Department of Gastroenter...

  6. Regional impairment of intrinsic functional connectivity strength in patients with chronic primary insomnia

    OpenAIRE

    Huang, Suhua; Zhou, Fuqing; Jiang, Jian; Huang, Muhua; Zeng, Xianjun; Ding, Shan; Gong, Honghan

    2017-01-01

    Suhua Huang,1 Fuqing Zhou,2,3 Jian Jiang,2,3 Muhua Huang,2,3 Xianjun Zeng,2,3 Shan Ding,1 Honghan Gong2,3 1Department of Radiology, Jiangxi Province Children’s Hospital, 2Department of Radiology, The First Affiliated Hospital, Nanchang University, 3Jiangxi Province Medical Imaging Research Institute, Nanchang, People’s Republic of China Abstract: Several neuroimaging studies have suggested that brain impairment and plasticity occur in patients with chronic primary insomn...

  7. Network Interdependency Modeling for Risk Assessment on Built Infrastructure Systems

    Science.gov (United States)

    2013-10-01

    required for this research. In the early stages of model development, simulated data was used in order to test the mathematical constructs for the...degraded service and increased cost. Finally, correlating decay and risk is no easy endeavor. Unlike actuaries in the insurance industry...Jiang (2001) and Haimes (2009) provide further details on the derivation of the IIM. Although mathematically sound, the IIM suffers from two

  8. Zhong et al., Afr J Tradit Complement Altern Med. (2014) 11(1):1-14

    African Journals Online (AJOL)

    cadewumi

    Yunqing Zhong*1, Xiufeng Wang2, Guanglan Xu,1, Bing Mao3, Wei Zhou3, Jie Min3, Hongli Jiang3, Xiang Diao4 , ..... due to COPD exacerbations, and 1 experienced a cerebrovascular accident. ..... the body (Makino T., 2005b; Hong et al., 2011). ... An, X., Zhang, A.L., Yang, A.W., Lin, L., Wu, D., Guo, X., Shergis, J.L., Thien, ...

  9. Author Index

    Indian Academy of Sciences (India)

    Huang, Y., 53. Hudec, L., 121. Hudec, R., 91, 121. Hughes, P. A., 5. Iguchi, S., 61. Jia, L. W., 309. Jiang, D. R., 261. Jorstad, S. G., 233, 239. Kang, H., 301. Kardashev, N. S., 105. Kong, M. Z., 209. Kovacs, Z., 189. Krichbaum, T. P., 29, 57. Krishan, V., 265. Kurtanidze, O., 67. Lähteenmäki, A., 105, 233, 239. Larinov, M. G., 105,.

  10. Rapid Identification of Vector-Borne Flaviviruses by Mass Spectrometry

    Science.gov (United States)

    2010-02-01

    Eastern, and Siberian subtypes [9]. Several tick-borne flaviviruses can also cause hemorrhagic disease. Important examples of these viruses include...assay. Identical base compositions within a column are the same color. Unique base compositions are shown with white backgrounds. (For interpretation...States, 1999e2005. Vector Borne Zoonotic Dis 2008;8:733e40. [18] Hofstadler SA, Sampath R, Blyn LB, Eshoo MW, Hall TA, Jiang Y, et al. TIGER : the

  11. A Reduced-Order Model for Evaluating the Dynamic Response of Multilayer Plates to Impulsive Loads

    Science.gov (United States)

    2016-04-12

    A REDUCED-ORDER MODEL FOR EVALUATING THE DYNAMIC RESPONSE OF MULTILAYER PLATES TO IMPULSIVE LOADS Weiran Jiang, Alyssa Bennett, Nickolas...innovative multilayer materials or structures to optimize the dynamic performance as a mechanism to absorb and spread energy from an impulsive load...models. • Optimizing the structural weight and levels of protection of the multilayer plates with a good combination of materials. Technical Approach 2016

  12. Automated Support for Rapid Coordination of Joint UUV Operation

    Science.gov (United States)

    2015-03-01

    Figure 20. MOOS -IvP Simulation Test Run Using the pMarineViewer Graphical User Interface, from [9...Global Positioning System ISR intelligence, surveillance and reconnaissance MAUV multiple AUVs Mbps megabits per second MOOS -IvP mission oriented...it to UUV coordination. D. Jiang et al. used the mission-oriented operating suite interval programming ( MOOS -IvP) architecture (open source) and a

  13. Paraganglioma of the vagina: a case report and review of the literature

    OpenAIRE

    Cai, Tao; Huang,Yu; Li,Yucong; Jiang,Qingming; Wang,Dong

    2014-01-01

    Tao Cai,1 Yucong Li,2 Qingming Jiang,3 Dong Wang,2 Yu Huang2 1Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, 2Department of Gynecologic Oncology, 3Department of Pathology, Chongqing Cancer Research Institute, Chongqing, People’s Republic of China Abstract: Vaginal paraganglioma is a rare and unusual tumor occurring in the vaginal wall. It is a solitary primary paraganglioma, especially in atypical sites. Herein, we report an unusual case o...

  14. Fundamental Studies of Transient, Atmospheric-Pressure, Small-Scale Plasmas

    Science.gov (United States)

    2017-01-23

    C. Jiang, R. Heller, J. Lane, and K. H. Schoenbach, " Ozone -free nitric oxide production using an atmospheric pressure surface discharge – a way to...Electrostatic modeling and energy-dependent studies showed that the direct and indirect electron-induced processes in the pulsed plasma jet are responsible for...Coupled sliding discharges : a scalable nonthermal plasma system utilizing positive and negative streamers on DISTRIBUTION A: Distribution

  15. Object-Based Benefits without Object-Based Representations

    OpenAIRE

    Alvarez, George Angelo; Fougnie, Daryl; Cormiea, Sarah M

    2012-01-01

    The organization of visual information into objects strongly influences visual memory: Displays with objects defined by two features (e.g. color, orientation) are easier to remember than displays with twice as many objects defined by one feature (Olson & Jiang, 2002). Existing theories suggest that this ‘object-benefit’ is based on object-based limitations in working memory: because a limited number of objects can be stored, packaging features together so that fewer objects have to be remembe...

  16. Inhibition of Fatty Acid Synthase in Prostate Cancer by Orlistat, a Novel Therapeutic

    Science.gov (United States)

    2007-11-01

    substrate specificity have been investigated by several groups. Chemical cross - linking, complementation and cryo-EM studies have led to proposals of the...feedback loop exists within these pathways [20, 34]. In addition, there may be a cross -talk with another type of lipid as evidence suggests that...American Journal of Surgical Pathology, 25, 1397–1404. 219. Jiang, Z., Li, C. Z., Fischer, A., Dresser , K., & Woda, B. A. (2005). Using an AMACR (P504S

  17. Fatty Acid Synthase Inhibitors Engage the Cell Death Program Through the Endoplasmic Reticulum

    Science.gov (United States)

    2007-12-01

    cross - linking, complementation and cryo-EM studies have led to proposals of the domain interactions within FAS10,11,16,17. The recent crystal structure...156 feedback loop exists within these pathways [20, 34]. In 157 addition, there may be a cross -talk with another type of lipid 158 as evidence...prostate carcinoma. American Journal of 1592 Surgical Pathology, 25, 1397–1404. 1593 219. Jiang, Z., Li, C. Z., Fischer, A., Dresser , K., & Woda, B. A. 1594

  18. Spartans in Darkness: American SIGINT and the Indochina War, 1945-1975. Series 6, Volume 7 (REDACTED)

    Science.gov (United States)

    2002-01-01

    all colo- nial financial , industrial, and agricultural activi- ties. As elsewhere in Asia, the primary economic activity was agriculture and was...were mired in China, and no end to the fighting was in sight. Jiang Jieshi refused to surrender, and the war was bleeding Japan dry financially . CU...istration was perplexed by the Ngo family’s shenanigans in Saigon. In the previous month there had been rumors of a coup by Diem’s broth- er, Nhu. On 11

  19. Horizontal subsurface flow constructed wetlands for mitigation of ...

    African Journals Online (AJOL)

    2008-12-22

    Dec 22, 2008 ... Results indicated that 39% of the total initially added amount of ametryn ... characteristics (Table 1), may result in the detection of poten- ... Water solubility at 20oC (g∙m-3) 204 ... culture, part of the resident liquid in CWs was lost, therefore ..... LIN T, WEN y, JIANG L, LI J, yANG S and ZHOu Q (2008) Study.

  20. Human Infection with Rickettsia felis, Kenya

    Science.gov (United States)

    2010-07-01

    Human Infection with Rickettsia felis, Kenya Allen L. Richards, Ju Jiang, Sylvia Omulo, Ryan Dare, Khalif Abdirah~a~, P:bdile Ali, Shanaaz K...infection with obligate intracellular rickettsiae , which are transmitted to humans by arthropod vectors (e.g., lice, fleas, ticks, and mites... Rickettsiae are associated with arthropods for a least a part of their life cycle and are passed to other arthropods by transovarial transmission or

  1. Rickettsia parkeri in Gulf Coast Ticks, Southeastern Virginia, USA

    Science.gov (United States)

    2011-05-01

    Rickettsia parkeri in Gulf Coast Ticks, Southeastern Virginia, USA Chelsea L. Wright, Robyn M. Nadolny, Ju Jiang, Allen L. Richards, Daniel E...Virginia. We found that 43.1% of the adult Gulf Coast ticks collected in the summer of 2010 carried Rickettsia parkeri, suggesting that persons living in...or visiting southeastern Virginia are at risk for infection with this pathogen. Rickettsia parkeri is an obligate intracellular bacterium belonging

  2. Detecting Rickettsia parkeri Infection from Eschar Swab Specimens

    Science.gov (United States)

    2013-05-01

    Detecting Rickettsia parkeri Infection from Eschar Swab Specimens Todd Myers, Tahaniyat Lalani, Mike Dent, Ju Jiang, Patrick L. Daly, Jason D...Maguire, and Allen L. Richards The typical clinical presentation of several spotted fever group Rickettsia infections includes eschars. Clinical...diagnosis by using an eschar swab specimen from patients infected with Rickettsia parkeri. Until 2004, all confirmed cases of tick-borne spotted

  3. Molecular Detection of Rickettsia amblyommii in Amblyomma americanum Parasitizing Humans

    Science.gov (United States)

    2010-01-01

    Detection of Rickettsia amblyommii in Amblyomma americanum Parasitizing Humans Ju Jiang~ Tamasin Yarina~ Melissa K. Miller,2 Ellen Y. Stromdahl? and...protein B gene (ompB) of Rickettsia amblyommii was employed to assess the threat of R. amblyommii exposure to humans parasitized by Amblyomma americanum...infection of and possibly disease in humans. Key Words: Amblyomma americanum-Lone star ticks-Real-time PCR- Rickettsia amblyommii. Introduction R

  4. Unbiased Combinatorial Genomic Approaches to Identify Alternative Therapeutic Targets within the TSC Signaling Network

    Science.gov (United States)

    2015-09-01

    endonuclease. Nat Biotechnol. 2013;31(3):230-2. Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, et al. Multiplex genome engineering using CRISPR/Cas systems...Res 42, e89 (2014)10.1093/nar/gku289). 13. L. Cong, F. A. Ran, D. Cox, S. Lin, R. Barretto, N. Habib , P. D. Hsu, X. Wu, W. Jiang, L. A. Marraffini

  5. Intranasal delivery of Huperzine A to the brain using lactoferrin-conjugated N-trimethylated chitosan surface-modified PLGA nanoparticles for treatment of Alzheimer’s disease

    OpenAIRE

    Meng,Qingqing; Wang,Aiping; Hua,Hongchen; Jiang,Ying; Wang,Yiyun; Mu,Hongjie; Wu,Zimei; Sun,Kaoxiang

    2018-01-01

    Qingqing Meng,1,* Aiping Wang,1,2,* Hongchen Hua,1 Ying Jiang,1 Yiyun Wang,1 Hongjie Mu,1 Zimei Wu,1 Kaoxiang Sun1 1School of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, People’s Republic of China; 2State Key Laboratory of Long-Acting and Targeting Drug Delivery System, Shandong Luye Pharmaceutical Co., Ltd, Yantai, People’s Republic of China *These authors contribute...

  6. Flexible SERS Substrates: Challenges and Opportunities

    Science.gov (United States)

    2016-01-28

    are still widely used due to the ease with which silver and gold nanoparticles can be produced. Nanoparticle inks are colloidal suspensions of...interactions between the analyte, silver nanoparticles, and a salt. This system has also been applied to detection of trace antibiotics for food safety...Cleanable SERS Substrates Based on Silver Nanoparticle Decorated Electrospun Nano-fibrous Membranes Chaoyang Jiang Porous electrospun nanofibrous

  7. Computing handbook computer science and software engineering

    CERN Document Server

    Gonzalez, Teofilo; Tucker, Allen

    2014-01-01

    Overview of Computer Science Structure and Organization of Computing Peter J. DenningComputational Thinking Valerie BarrAlgorithms and Complexity Data Structures Mark WeissBasic Techniques for Design and Analysis of Algorithms Edward ReingoldGraph and Network Algorithms Samir Khuller and Balaji RaghavachariComputational Geometry Marc van KreveldComplexity Theory Eric Allender, Michael Loui, and Kenneth ReganFormal Models and Computability Tao Jiang, Ming Li, and Bala

  8. Recent Research in Behind-Armor Blunt Trauma and Traumatic Brain Injury

    Science.gov (United States)

    2014-02-01

    Injury. Natl. Tech. Inf. Serv. 2006, ADA481896. 20. Cernak, I.; Wang, Z.; Jiang, J.; Bian, X.; Savic , J. Ultrastructural and Functional Characteristics...Malicevic, Z.; Savic J. Experimental Magnesium Depletion in Adult Rabbits Caused by Blast Overpressure. Magnes. Res. 1995, 8 (4), 249–259. 34. Cernak, I... Savic , J.; Malicevic, Z.; Zunic, G.; Radosevic, P.; Ivanovic, I.; Davidovic, L. Involvement of the Central Nervous System in the General Response

  9. Feature Binding and the Hebb Repetition Effect

    OpenAIRE

    Barrett, Maeve

    2008-01-01

    Previous studies have found no evidence that long-term learning of integrated objects and individual features benefit visual short term memory tasks (Logie, Brockmole, & Vandenbroucke, in press; Olson & Jiang, 2004; Treisman, 2006). These findings may have been due to stimulus interference as a restricted number of features were utilised in these studies to form objects in the stimulus arrays. In these studies, participants would have needed to break apart the features of several objects in a...

  10. Design, synthesis, and evaluation of VEGFR-targeted macromolecular MRI contrast agent based on biotin?avidin-specific binding

    OpenAIRE

    Liu, Yongjun; Wu, Xiaoyun; Sun, Xiaohe; Wang, Dan; Zhong, Ying; Jiang, Dandan; Wang, Tianqi; Yu, Dexin; Zhang, Na

    2017-01-01

    Yongjun Liu,1 Xiaoyun Wu,1 Xiaohe Sun,1 Dan Wang,1 Ying Zhong,1 Dandan Jiang,1 Tianqi Wang,1 Dexin Yu,2 Na Zhang1 1School of Pharmaceutical Science, Shandong University, 2Department of Radiology Medicine, Qilu Hospital, Jinan, People’s Republic of China Abstract: Developing magnetic resonance imaging (MRI) contrast agents with high relaxivity and specificity was essential to increase MRI diagnostic sensitivity and accuracy. In this study, the MRI contrast agent, vascular endotheli...

  11. Advertising execution styles as a reflection of culture : Cross-cultural analysis of messaging app advertising preferences in South Korea and China

    OpenAIRE

    Kivinen, Sofia

    2014-01-01

    Increased globalization and the thought of converging values has lead marketing practitioners and academics to consider more standardized approaches to marketing and advertising strategies. Even though cultures seem to evolve closer to each other, cultural diversity still exists. Advertising reflects and influences our cultural values and therefore it cannot be ignored when building effective advertising. Results show that culture impacts execution more than creative strategy (Wei & Jiang...

  12. Security analysis and improvement of a privacy authentication scheme for telecare medical information systems.

    Science.gov (United States)

    Wu, Fan; Xu, Lili

    2013-08-01

    Nowadays, patients can gain many kinds of medical service on line via Telecare Medical Information Systems(TMIS) due to the fast development of computer technology. So security of communication through network between the users and the server is very significant. Authentication plays an important part to protect information from being attacked by malicious attackers. Recently, Jiang et al. proposed a privacy enhanced scheme for TMIS using smart cards and claimed their scheme was better than Chen et al.'s. However, we have showed that Jiang et al.'s scheme has the weakness of ID uselessness and is vulnerable to off-line password guessing attack and user impersonation attack if an attacker compromises the legal user's smart card. Also, it can't resist DoS attack in two cases: after a successful impersonation attack and wrong password input in Password change phase. Then we propose an improved mutual authentication scheme used for a telecare medical information system. Remote monitoring, checking patients' past medical history record and medical consultant can be applied in the system where information transmits via Internet. Finally, our analysis indicates that the suggested scheme overcomes the disadvantages of Jiang et al.'s scheme and is practical for TMIS.

  13. The KdV—Burgers equation in a modified speed gradient continuum model

    International Nuclear Information System (INIS)

    Lai Ling-Ling; Ge Hong-Xia; Cheng Rong-Jun; Li Zhi-Peng

    2013-01-01

    Based on the full velocity difference model, Jiang et al. put forward the speed gradient model through the micro-macro linkage (Jiang R, Wu Q S and Zhu Z J 2001 Chin. Sci. Bull. 46 345 and Jiang R, Wu Q S and Zhu Z J 2002 Trans. Res. B 36 405). In this paper, the Taylor expansion is adopted to modify the model. The backward travel problem is overcome by our model, which exists in many higher-order continuum models. The neutral stability condition of the model is obtained through the linear stability analysis. Nonlinear analysis shows clearly that the density fluctuation in traffic flow leads to a variety of density waves. Moreover, the Korteweg-de Vries—Burgers (KdV—Burgers) equation is derived to describe the traffic flow near the neutral stability line and the corresponding solution for traffic density wave is derived. The numerical simulation is carried out to investigate the local cluster effects. The results are consistent with the realistic traffic flow and also further verify the results of nonlinear analysis

  14. A secure chaotic maps and smart cards based password authentication and key agreement scheme with user anonymity for telecare medicine information systems.

    Science.gov (United States)

    Li, Chun-Ta; Lee, Cheng-Chi; Weng, Chi-Yao

    2014-09-01

    Telecare medicine information system (TMIS) is widely used for providing a convenient and efficient communicating platform between patients at home and physicians at medical centers or home health care (HHC) organizations. To ensure patient privacy, in 2013, Hao et al. proposed a chaotic map based authentication scheme with user anonymity for TMIS. Later, Lee showed that Hao et al.'s scheme is in no provision for providing fairness in session key establishment and gave an efficient user authentication and key agreement scheme using smart cards, in which only few hashing and Chebyshev chaotic map operations are required. In addition, Jiang et al. discussed that Hao et al.'s scheme can not resist stolen smart card attack and they further presented an improved scheme which attempts to repair the security pitfalls found in Hao et al.'s scheme. In this paper, we found that both Lee's and Jiang et al.'s authentication schemes have a serious security problem in that a registered user's secret parameters may be intentionally exposed to many non-registered users and this problem causing the service misuse attack. Therefore, we propose a slight modification on Lee's scheme to prevent the shortcomings. Compared with previous schemes, our improved scheme not only inherits the advantages of Lee's and Jiang et al.'s authentication schemes for TMIS but also remedies the serious security weakness of not being able to withstand service misuse attack.

  15. New microbial resource: microbial diversity, function and dynamics in Chinese liquor starter.

    Science.gov (United States)

    Huang, Yuhong; Yi, Zhuolin; Jin, Yanling; Zhao, Yonggui; He, Kaize; Liu, Dayu; Zhao, Dong; He, Hui; Luo, Huibo; Zhang, Wenxue; Fang, Yang; Zhao, Hai

    2017-11-06

    Traditional Chinese liquor (Baijiu) solid state fermentation technology has lasted for several thousand years. The microbial communities that enrich in liquor starter are important for fermentation. However, the microbial communities are still under-characterized. In this study, 454 pyrosequencing technology was applied to comprehensively analyze the microbial diversity, function and dynamics of two most-consumed liquor starters (Jiang- and Nong-flavor) during production. In total, 315 and 83 bacterial genera and 72 and 47 fungal genera were identified in Jiang- and Nong-flavor liquor starter, respectively. The relatively high diversity was observed when the temperature increased to 70 and 62 °C for Jiang- and Nong-flavor liquor starter, respectively. Some thermophilic fungi have already been isolated. Microbial communities that might contribute to ethanol fermentation, saccharification and flavor development were identified and shown to be core communities in correlation-based network analysis. The predictively functional profile of bacterial communities showed significant difference in energy, carbohydrate and amino acid metabolism and the degradation of aromatic compounds between the two kinds of liquor starters. Here we report these liquor starters as a new functionally microbial resource, which can be used for discovering thermophilic and aerobic enzymes and for food and feed preservation.

  16. Avtograf na Teodor Hagiopetrit ot C''rkovnija istoriko-arheologičeski Institut v Sofija, CIAI 949

    Directory of Open Access Journals (Sweden)

    Džurova Aksinija

    2013-01-01

    Full Text Available Subject of this article is the copy of Four Gospels preserved at the Church Institute in Sofia (gr. 949, which was displayed in the Brilliance of Byzantium Exhibition organized during the 22nd International Congress of Byzantine Studies (August 22 - 27, 2011 and which we assumed to have been produced by the hand of one of the most famous scribes at the end of the 13th and the beginning of the 14th century, i.e. Theodore Hagiopetrites. The type of the script employed in the Four Gospels at the Church Institute (CHAI gr. 949 is in the so-called by L. Politis unique ‘Hagiopetrites Style’. Although the manuscript does not contain a colophon, comparison to the manuscripts of Theodore Hagiopetrites known to us and especially to Cod. D. gr. 29 (Olim. Kos. 35 at the Ivan Dujčev Centre - an autograph of the scribe of 1307, as well as to another manuscript from Saint Petersburg, Cod. gr. of ASUSSR, No 10/667 of the 14th century, provides good reasons to assume that the Four Gospels manuscript (CHAI gr. 949 was also produced by Theodore Hagiopetrites. Our certainty was further substantiated after we had studied in situ the Four Gospels from Academician N. P. Likhachev’s archive published by Igor Medvedev in the collection ‘ In Memoriam Ivan Dujčev’ of 1988 which is currently kept under No 10/667 in the Archive of the Leningrad Section of the Institute of History at the Russian Academy of Science. Having compared the illumination and the specifics of motif stylization, as well as the specific colouring, we could assert that the two manuscripts manifest pronounced similarities. Thereby, the 27 manuscripts by T. Hagiopetrites published by R. Nelson should also be supplemented by the Four Gospels at the Church Institute (CHAI gr. 949 in addition to the Apostle Lectionary of 1307, autograph of Theodore Hagiopetrites at the Dujčev Centre, Cod. D. gr. 29 (Olim. Kos. 35, which R. Nelson briefly mentioned in his preface, and the Saint Petersburg Four

  17. RETRACTED: Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population.

    Science.gov (United States)

    Zhong, Weiqiang; Jiang, Zongpei; Zhou, Tian-Biao

    2015-12-01

    This article has been included in a multiple retraction: Weiqiang Zhong, Zongpei Jiang, and Tian-Biao Zhou Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population Journal of Renin-Angiotensin-Aldosterone System 1470320314566019, first published on January 26, 2015 doi: 10.1177/1470320314566019 This article has been retracted at the request of the Editors and the Publisher. After conducting a thorough investigation, SAGE found that the submitting authors of a number of papers published in the Journal of the Renin-Angiotensin Aldosterone System ( JRAAS) (listed below) had supplied fabricated contact details for their nominated reviewers. The Editors accepted these papers based on the reports supplied by the individuals using these fake reviewer email accounts. After concluding that the peer review process was therefore seriously compromised, SAGE and the journal Editors have decided to retract all affected articles. Online First articles (these articles will not be published in an issue) Wenzhuang Tang, Tian-Biao Zhou, and Zongpei Jiang Association of the angiotensinogen M235T gene polymorphism with risk of diabetes mellitus developing into diabetic nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563426, first published on December 18, 2014 doi: 10.1177/1470320314563426 Tian-Biao Zhou, Hong-Yan Li, Zong-Pei Jiang, Jia-Fan Zhou, Miao-Fang Huang, and Zhi-Yang Zhou Role of renin-angiotensin-aldosterone system inhibitors in radiation nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563424, first published on December 18, 2014 doi: 10.1177/1470320314563424 Weiqiang Zhong, Zongpei Jiang, and Tian-Biao Zhou Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population Journal of Renin-Angiotensin-Aldosterone System 1470320314566019, first published on January 26, 2015 doi: 10

  18. RETRACTED: Relationship between the ACE I/D gene polymorphism and T1DN susceptibility/risk of T1DM developing into T1DN in the Caucasian population.

    Science.gov (United States)

    Zhou, Tian-Biao; Guo, Xue-Feng; Jiang, Zongpei; Li, Hong-Yan

    2015-12-01

    The following article has been included in a multiple retraction: Tian-Biao Zhou, Xue-Feng Guo, Zongpei Jiang, and Hong-Yan Li Relationship between the ACE I/D gene polymorphism and T1DN susceptibility/risk of T1DM developing into T1DN in the Caucasian population Journal of Renin-Angiotensin-Aldosterone System 1470320314563425, first published on February 1, 2015 doi: 10.1177/1470320314563425 This article has been retracted at the request of the Editors and the Publisher. After conducting a thorough investigation, SAGE found that the submitting authors of a number of papers published in the Journal of the Renin-Angiotensin Aldosterone System ( JRAAS) (listed below) had supplied fabricated contact details for their nominated reviewers. The Editors accepted these papers based on the reports supplied by the individuals using these fake reviewer email accounts. After concluding that the peer review process was therefore seriously compromised, SAGE and the journal Editors have decided to retract all affected articles. Online First articles (these articles will not be published in an issue) Wenzhuang Tang, Tian-Biao Zhou, and Zongpei Jiang Association of the angiotensinogen M235T gene polymorphism with risk of diabetes mellitus developing into diabetic nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563426, first published on December 18, 2014 doi: 10.1177/1470320314563426 Tian-Biao Zhou, Hong-Yan Li, Zong-Pei Jiang, Jia-Fan Zhou, Miao-Fang Huang, and Zhi-Yang Zhou Role of renin-angiotensin-aldosterone system inhibitors in radiation nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563424, first published on December 18, 2014 doi: 10.1177/1470320314563424 Weiqiang Zhong, Zongpei Jiang, and Tian-Biao Zhou Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population Journal of Renin-Angiotensin-Aldosterone System 1470320314566019, first published on January

  19. Improving cold chain systems: Challenges and solutions.

    Science.gov (United States)

    Ashok, Ashvin; Brison, Michael; LeTallec, Yann

    2017-04-19

    While a number of new vaccines have been rolled out across the developing world (with more vaccines in the pipeline), cold chain systems are struggling to efficiently support national immunization programs in ensuring the availability of safe and potent vaccines. This article reflects on the Clinton Health Access Initiative, Inc. (CHAI) experience working since 2010 with national immunization programs and partners to improve vaccines cold chains in 10 countries-Ethiopia, Nigeria, Kenya, Malawi, Tanzania, Uganda, Cameroon, Mozambique, Lesotho and India - to identify the root causes and solutions for three common issues limiting cold chain performance. Key recommendations include: Collectively, the solutions detailed in this article chart a path to substantially improving the performance of the cold chain. Combined with an enabling global and in-country environment, it is possible to eliminate cold chain issues as a substantial barrier to effective and full immunization coverage over the next few years. Copyright © 2017. Published by Elsevier Ltd.

  20. Transforming cold chain performance and management in lower-income countries.

    Science.gov (United States)

    Brison, Mike; LeTallec, Yann

    2017-04-19

    In many countries, one of the common factors limiting full and equitable access to effective immunization is the existence of gaps in cold chain and logistics (CCL) systems. This article focuses on the critical contribution that better management of CCL performance can make in addressing these barriers, as well as some essential practices needed to achieve and sustain these gains. These include (i) an emphasis on continuous improvement in CCL performance indicators, (ii) strong coordination and accountability across multiple stakeholders, and (iii) making the most of limited financial resources. This article is informed by the Clinton Health Access Initiative's (CHAI's) experience working with National Immunization Programs (NIPs) and immunization partners to improve the effectiveness and efficiency of CCL systems (including CCE deployment and maintenance, temperature monitoring and control, stock management and distribution) across ten Gavi-supported "focus" countries. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  1. Essays on the frontiers of modern astrophysics and cosmology

    CERN Document Server

    Mathew, Santhosh

    2014-01-01

    This book is a collection of engaging and intriguing essays that describe an intellectual journey from the beginning to the end of universe. It is the product of an ongoing effort to know our place in the universe and share with readers the underpinnings of the magnificent cosmos where we are given a chance to exist only very briefly. The essays incorporate a group of challenging ideas that modern physics and cosmology are struggling to understand, in a unique way that incorporates mythological, religious, and philosophical perspectives. The author relies on a simple and powerful philosophy that we are part of the universe and the universe is part of us.   This wonderful collection of essays provides a journey through the current frontiers of modern astrophysics and cosmology. Its depiction of the most important unsolved mysteries about our place in the Universe is peppered with original insights and philosophical perspectives, making it an intellectual treat. – Avi Loeb, Professor, Harvard University Chai...

  2. Long-Range Corrected Hybrid Density Functionals with Damped Atom-Atom Dispersion Corrections

    Energy Technology Data Exchange (ETDEWEB)

    Chai, Jeng-Da; Head-Gordon, Martin

    2008-06-14

    We report re-optimization of a recently proposed long-range corrected (LC) hybrid density functionals [J.-D. Chai and M. Head-Gordon, J. Chem. Phys. 128, 084106 (2008)] to include empirical atom-atom dispersion corrections. The resulting functional, {omega}B97X-D yields satisfactory accuracy for thermochemistry, kinetics, and non-covalent interactions. Tests show that for non-covalent systems, {omega}B97X-D shows slight improvement over other empirical dispersion-corrected density functionals, while for covalent systems and kinetics, it performs noticeably better. Relative to our previous functionals, such as {omega}B97X, the new functional is significantly superior for non-bonded interactions, and very similar in performance for bonded interactions.

  3. Maternal and child health from a human rights perspective: the Indian scenario and nuns as community health enablers

    Directory of Open Access Journals (Sweden)

    Tomi Thomas

    2016-01-01

    Full Text Available All women need access to antenatal care in pregnancy, skilled care during childbirth, and care and support in the weeks after childbirth. This discussion tries to look into the life context of maternal and child health, and the health scenario of women/girl children in general in India from the perspective of Human Rights. Currently, most of the public and private health experts and organizations do not talk and act on the human rights perspective of health service delivery. Reversely, only a very few rights-based organizations advocate directly the right to health for the marginalized. Within the framework of a rights-based approach, the right to (Maternal Health on practical terms means “Availability, Accessibility, Acceptability and Quality.” Concluding, in the background of the Catholic Health Association of India (CHAI, the discussion also focuses on how the nun nurses play their role as “Community Health Enablers” to improve the situation.

  4. Inner happiness among Thai elderly.

    Science.gov (United States)

    Gray, Rossarin Soottipong; Rukumnuaykit, Pungpond; Kittisuksathit, Sirinan; Thongthai, Varachai

    2008-09-01

    This study, based on data collected in 2005 from Chai Nat province, examines the level of happiness of the Thai elderly population and its relationship to various external and internal factors. It was found that mean happiness was slightly above a feeling of "neutral." According to multiple regression analyses, external factors including economic hardship, living arrangements, functional ability, perceived social environment, and consumerism significantly influence the level of happiness. The strongest predictor of happiness is, however, the internal factor-that is, a feeling of relative poverty when compared to their neighbors. Controlling for demographic and all external factors, the respondents who do not feel poor show the highest level of happiness compared to those who feel as poor as or poorer than their neighbors. This is self-interpreted as a feeling of contentment with what one has, which has been influenced by Thai culture, which is pervaded by Buddhism.

  5. PDB: CBRC-CJAC-01-0391 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CJAC-01-0391 1FFX,1IA0,1JFF,1SA0,1SA1,1TUB,1TVK,2WBE,1Z2B,3DCO,3DU7,3E22, Region:421-804(Identity...=82%) PDB:1FFX Chain:B (X-ray Resolution=3.95),Region:421-804(Identity=82%) PDB:1IA0 Chai...n:B (EM Resolution=15.00),Region:421-804(Identity=82%) PDB:1JFF Chain:B (EM Resolution=3.50),Region:421-804(Identity...=82%) PDB:1SA0 Chain:B (X-ray Resolution=3.58),Region:421-804(Identity=82...%) PDB:1SA1 Chain:B (X-ray Resolution=4.20),Region:421-788(Identity=82%) PDB:1TUB Chain:B (EM Resolution=3.70),Region:421-788(Identit

  6. Néron Models and Base Change

    DEFF Research Database (Denmark)

    Halle, Lars Halvard; Nicaise, Johannes

    Presenting the first systematic treatment of the behavior of Néron models under ramified base change, this book can be read as an introduction to various subtle invariants and constructions related to Néron models of semi-abelian varieties, motivated by concrete research problems and complemented...... with explicit examples. Néron models of abelian and semi-abelian varieties have become an indispensable tool in algebraic and arithmetic geometry since Néron introduced them in his seminal 1964 paper. Applications range from the theory of heights in Diophantine geometry to Hodge theory. We focus specifically...... on Néron component groups, Edixhoven’s filtration and the base change conductor of Chai and Yu, and we study these invariants using various techniques such as models of curves, sheaves on Grothendieck sites and non-archimedean uniformization. We then apply our results to the study of motivic zeta functions...

  7. Supply chain configuration concepts, solutions, and applications

    CERN Document Server

    Chandra, Charu

    2016-01-01

    This book discusses the models and tools available for solving configuration problems, emphasizes the value of model integration to obtain comprehensive and robust configuration decisions, proposes solutions for supply chain configuration in the presence of stochastic and dynamic factors, and illustrates application of the techniques discussed in applied studies. It is divided into four parts, which are devoted to defining the supply chain configuration problem and identifying key issues, describing solutions to various problems identified, proposing technologies for enabling supply chain confirmations, and discussing applied supply chain configuration problems. Its distinguishing features are: an explicit focus on the configuration problem an in-depth coverage of configuration models an emphasis on model integration and application of information modeling techniques in decision-making New to this edition is Part II: Technologies, which introduces readers to various technologies being utilized for supply chai...

  8. Dicty_cDB: Contig-U12567-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available S1) RecName: Full=Protein lava lamp; &AE014298_609(AE01429... 36 4.2 EU708920_1( EU708920 |pid:none) Canine rotavirus...none) Mus musculus B16 F10Y cells cDNA, ... 35 7.1 DQ005106_1( DQ005106 |pid:none) Human rotavirus... Full=Myosin-9; AltName: Full=Myosin heavy chai... 35 7.1 AY787649_1( AY787649 |pid:none) Human rotavirus A ...7211_1( AK147211 |pid:none) Mus musculus 15 days embryo liver ... 35 7.1 EF554090_1( EF554090 |pid:none) Human rotavirus...rotein 3; Short=... 35 7.1 EF672579_1( EF672579 |pid:none) Human rotavirus A strain DS-1 non-... 35 7.1 ( Q6

  9. Characterisation of a new alkoxide sol-gel hydroxyapatite

    International Nuclear Information System (INIS)

    Green, D.D.; Kannangara, G.S.K.; Milev, A.; Ben-Nissan, B.

    1999-01-01

    Hydroxyapatite (HAp) coatings have been used to promote bone growth and fixation towards implant surfaces to encourage faster recovery times for the recipient. Current coating processing techniques, capable of producing thin HAp layers are pulsed-laser deposition and sputtering (high-temperature processing). Other technologies are in vitro methods, electrodeposition and sol-gel, due to the fact that these techniques utilise lower processing temperatures they avoid structural instabilities of HAp at elevated temperatures. The term sol-gel encompasses any process of producing ceramic materials (single and mixed oxides, as well as non-oxides e.g. nitrides) from solutions. The sol-gel process was first identified by Ebelman, and has been used to produce ceramic powders, coatings, and bulk materials including glasses. The implementation of a sol-gel methodology enables increased stoichiometry and homogeneity, while having the ability to coat complex shapes. Sol-gel hydroxyapatite reported by Chai et al. employed tri ethyl phosphite [ P(OEt) 3 ] as the staring phosphorus alkoxide precursor, whereby it was established that in order to obtain monophasic hydroxyapatite upon firing there must be a 24 hour ripening period. The ripening period was determined to be an equilibrium step whereby the equilibrium intermediate phase lied in favour of a diethyl phosphite arrangement (species) within the sol. Therefore, the work here under taken was to produce hydroxyapatite using diethyl phosphite [HOP(OEt) 2 ] as a starting alkoxide precursor with a final aim to reduce or eliminate the ageing period as observed by Chai et al in P(OEt) 3 solutions

  10. Mapping of QTLs for Seed Phorbol Esters, a Toxic Chemical in Jatropha curcas (L.).

    Science.gov (United States)

    Amkul, Kitiya; Laosatit, Kularb; Somta, Prakit; Shim, Sangrea; Lee, Suk-Ha; Tanya, Patcharin; Srinives, Peerasak

    2017-08-18

    Jatropha ( Jatropha curcas L.) is an oil-bearing plant that has potential to be cultivated as a biodiesel crop. The seed cake after oil extraction has 40-50% protein that can be used in animal feeds. A major limitation in utilizing the cake is the presence of phorbol esters (PE), a heat-tolerant toxic chemical. To identify the quantitative trait loci (QTLs) for PE, we constructed a genetic linkage map from an F₂ population of 95 individuals from a cross "Chai Nat" × "M10" using 143 simple sequence repeat (SSR) markers. M10 is low in seed PE while Chai Nat is high. Seeds from each F₂ individual were quantified for PE content by high performance liquid chromatography. A single marker analysis revealed five markers from linkage group 3 (LG3) and nine markers from LG8 associated with seed PE. Inclusive composite interval mapping identified two QTLs, each on LG3 ( qPE3.1 ) and LG8 ( qPE8.1 ) responsible for the PE. qPE3.1 and qPE8.1 accounted for 14.10%, and 15.49% of total variation in seed PE, respectively. Alelle(s) from M10 at qPE3.1 increased seed PE, while at qPE8.1 decreased seed PE. qPE3.1 is a new loci for PE, while qPE8.1 is the same locus with that reported recently for PE.

  11. RETRACTED: Association of the ACE I/D gene polymorphism with sepsis susceptibility and sepsis progression.

    Science.gov (United States)

    Yang, Chun-Hua; Zhou, Tian-Biao

    2015-12-01

    This article has been included in a multiple retraction: Chun-Hua Yang and Tian-Biao Zhou Association of the ACE I/D gene polymorphism with sepsis susceptibility and sepsis progression Journal of Renin-Angiotensin-Aldosterone System 1470320314568521, first published on February 3, 2015 doi: 10.1177/1470320314568521 This article has been retracted at the request of the Editors and the Publisher. After conducting a thorough investigation, SAGE found that the submitting authors of a number of papers published in the Journal of the Renin-Angiotensin Aldosterone System ( JRAAS) (listed below) had supplied fabricated contact details for their nominated reviewers. The Editors accepted these papers based on the reports supplied by the individuals using these fake reviewer email accounts. After concluding that the peer review process was therefore seriously compromised, SAGE and the journal Editors have decided to retract all affected articles. Online First articles (these articles will not be published in an issue) Wenzhuang Tang, Tian-Biao Zhou, and Zongpei Jiang Association of the angiotensinogen M235T gene polymorphism with risk of diabetes mellitus developing into diabetic nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563426, first published on December 18, 2014 doi: 10.1177/1470320314563426 Tian-Biao Zhou, Hong-Yan Li, Zong-Pei Jiang, Jia-Fan Zhou, Miao-Fang Huang, and Zhi-Yang Zhou Role of renin-angiotensin-aldosterone system inhibitors in radiation nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563424, first published on December 18, 2014 doi: 10.1177/1470320314563424 Weiqiang Zhong, Zongpei Jiang, and Tian-Biao Zhou Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population Journal of Renin-Angiotensin-Aldosterone System 1470320314566019, first published on January 26, 2015 doi: 10.1177/1470320314566019 Tian-Biao Zhou, Xue-Feng Guo, Zongpei

  12. WE-C-TOUR-I-01: Dosimters for QC in Diagnostic Imaging

    International Nuclear Information System (INIS)

    Jiang, X.

    2016-01-01

    Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Adrien Sanchez, University of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

  13. WE-C-TOUR-I-00: Exhibit Hall Guided Tours-Dosimters for QC in Diagnostic Imaging (Wednesday)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2016-06-15

    Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Adrien Sanchez, University of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

  14. WE-C-TOUR-I-01: Dosimters for QC in Diagnostic Imaging

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, X. [Ohio State University (United States)

    2016-06-15

    Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Adrien Sanchez, University of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

  15. WE-C-TOUR-I-00: Exhibit Hall Guided Tours-Dosimters for QC in Diagnostic Imaging (Wednesday)

    International Nuclear Information System (INIS)

    2016-01-01

    Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Adrien Sanchez, University of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

  16. TU-E-TOUR-I-00: Exhibit Hall Guided Tours-Dosimters for QC in Diagnostic Imaging (Tuesday)

    International Nuclear Information System (INIS)

    2016-01-01

    Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Christina Sammet, Lurie Children’s Hospital of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

  17. TU-E-TOUR-I-00: Exhibit Hall Guided Tours-Dosimters for QC in Diagnostic Imaging (Tuesday)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2016-06-15

    Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Christina Sammet, Lurie Children’s Hospital of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

  18. Modelling and verification of melanin concentration on human skin type

    CSIR Research Space (South Africa)

    Karsten, AE

    2012-03-01

    Full Text Available exposure to long-wave ultraviolet and visible light. J. Invest. Dermatol. 39, 13 435-443. 14 30. Lavker, R. M. and K. H. Kaidbey (1982) Redistribution of melanosomal complexes 15 within keratinocytes following UV-A irradiation: A possible mechanism..., 1146-1154. 10 20. Salomatina, E., B. Jiang, J. Novak, and A. N. Yaroslavsky (2006) Optical properties of 11 normal and cancerous human skin in the visible and near-infrared spectral range. J. 12 Biomed. Opt. 11. 13 21. Young, A. R. (1997...

  19. Thismia huangii (Thismiaceae, a New Species from Taiwan

    Directory of Open Access Journals (Sweden)

    Po-Yi Chiang

    2011-06-01

    Full Text Available Thismia Griff.(Thismiaceae, comprises about 35 species. Heretofore, one species was recorded from Kaohsiung County in southern Taiwan. In the course of our botanical inventory, a new species, Thismia huangii P. Y. Jiang et T. H. Hsieh, was collected from northwestern part of the island. Thismia huangii is close to T. rodwayi F. von Muller and T. americana Pfeifer, but can be distinguished from the latter by its orange perianth, dark-orange or red annulus, long hairy connectives, and stigma lobe with one long hair. A taxonomic description, line drawing, pollen morphology in SEM observation, chromosome number, distribution information, and color photographs of the floral characters are provided.

  20. CHILI: China Lijiang IFU

    Science.gov (United States)

    Hao, Lei

    2014-07-01

    Wide-field IFU technology on medium-size telescope provides a unique science capability that compliments larger future facilities. Here I introduce a program to employ a VIRUS-like unit on the 2.4 meter telescope in GaoMeiGu Observatory in LiJiang, China. We name the instrument "CHILI (China Lijiang IFU)". It will be an IFU with very large field of view at 1.8'x3.6'. We discuss its science capabilities and its potential benefit to the Chinese astronomical community.

  1. A new species of Mollitrichosiphum Suenaga from Taiwan Island (Hemiptera, Aphididae), based on morphological characteristics and DNA sequences

    Science.gov (United States)

    Jiang, Li-Yun; Chen, Jing; Qiao, Ge-Xia

    2015-01-01

    Abstract A new species of Mollitrichosiphum Suenaga, Mollitrichosiphum tumorisiphum Qiao & Jiang, sp. n., from Fagus longipetiolata in Taiwan island is described. Siphunculi of Mollitrichosiphum tumorisiphum in alatae are distinctly swollen on the distal part, unlike those of the other known species in the genus. Updated keys to apterous and alate viviparous females of all known Chinese species of Mollitrichosiphum are provided. The specimens studied are deposited in the National Zoological Museum of China, Institute of Zoology, Chinese Academy of Sciences, Beijing, China and the Natural History Museum, London, United Kingdom. PMID:26478705

  2. Research on optimal investment path of transmission corridor under the global energy Internet

    Science.gov (United States)

    Huang, Yuehui; Li, Pai; Wang, Qi; Liu, Jichun; Gao, Han

    2018-02-01

    Under the background of the global energy Internet, the investment planning of transmission corridor from XinJiang to Germany is studied in this article, which passes through four countries: Kazakhstan, Russia, Belarus and Poland. Taking the specific situation of different countries into account, including the length of transmission line, unit construction cost, completion time, transmission price, state tariff, inflation rate and so on, this paper constructed a power transmission investment model. Finally, the dynamic programming method is used to simulate the example, and the optimal strategies under different objective functions are obtained.

  3. The 19th Party Congress

    DEFF Research Database (Denmark)

    Brødsgaard, Kjeld Erik; Høyrup Christensen, Nis

    2017-01-01

    veteran leaders such as Wang Qishan (69) continue to serve on the committee? Would Xi Jinping pack the Politburo and the PSC with his own close allies, or would he try to achieve a factional balance observing the interests of former leaders such as Jiang Zemin and Hu Jintao? There was also much....... Such a report is usually a long document setting out the Party's priorities and policy objectives for the next five-year period. Would Xi Jinping's report signal new policy initiatives, and would it outline strategic guidelines reaching beyond 2022? This article examines these questions and assesses the future...

  4. Preclinical and Clinical Development of Low Dose Methamphetamine for the Treatment of Traumatic Brain Injury

    Science.gov (United States)

    2014-04-01

    complex and allows Bcl-xl to promote cell survival (Jeong et al., 2008; Koh et al., 2008; Uchiyama et al., 2004). pAKT also activates inhibitors of...forebrain ischemia in the Mongolian gerbil. Neurosci. Lett. 342, 25e28. Koh , P.O., Cho, J.H., Won, C.K., Lee, H.J., Sung, J.H., Kim, M.O., 2008. Estradiol...model of focal embolic cerebral ischemia. Brain Res. 766, 83e92. Zhang, Z., Zhang, R.L., Jiang, Q., Raman , S.B., Cantwell, L., Chopp, M., 1997b. A new

  5. JPRS Report China

    Science.gov (United States)

    1989-12-19

    Japanese Investment 90OH0029A Beijing GUOJIMAOYI WENTI [INTERNATIONAL TRADE JOURNAL ] in Chinese No 7-8, 30Aug89pp 12-14 [Article by Zhang Dong...beginning of July showed that in recent years the practice of building private homes by cadres has flour - ished, with two-thirds of the cities and...the mess hall; and the money for the fountain pen ink and for glue used by the cadres came from the individual’s own pocket. Once, Young Jiang

  6. Computer-Aided Software Evolution Based on Inferred Dependencies

    Science.gov (United States)

    1999-12-01

    of Technology, Taoyuan, Taiwan, 1980 M.B.A., National Defense Management College, Taipei, Taiwan, 1986 Submitted in partial fulfillment of the...JGuoJiang £3 Program Rles 1] PRCCaption.txt ^3 host-news ■BEH3JB1EH1 gpshcd98. pdf i_]Jlip E3 Video *) PSHCD98.ps _JJws20 Ü ~PDTS874.tmp ljlQuickTime30.exe...115 O’Keefe Building Georgia Institute of Technology Atlanta, GA 30332-0800 4. Dr. David Hislop Army Research Office 4300 S. Miami Blvd. Research

  7. From Foreground to Background: How Task-Neutral Context Influences Contextual Cueing of Visual Search

    OpenAIRE

    Zang, Xuelian; Geyer, Thomas; Assump??o, Leonardo; M?ller, Hermann J.; Shi, Zhuanghua

    2016-01-01

    Selective attention determines the effectiveness of implicit contextual learning (e.g., Jiang and Leung, 2005). Visual foreground-background segmentation, on the other hand, is a key process in the guidance of attention (Wolfe, 2003). In the present study, we examined the impact of foreground-background segmentation on contextual cueing of visual search in three experiments. A visual search display, consisting of distractor ‘L’s and a target ‘T’, was overlaid on a task-neutral cuboid on the s...

  8. Time Transfer from Combined Analysis of GPS and TWSTFT Data

    Science.gov (United States)

    2008-12-01

    2005/429 and BEFPI/2007/040 of the Consellería de Empresa , Universidad y Ciencia of the Generalitat Valenciana. The authors also acknowledge the time...and Z. Jiang2 1University of Alicante, Spain, E-mail: carmen.martinez@ua.es 2Bureau International des Poids et Mesures, France, E-mail: zjiang...failing to comply with a collection of information if it does not display a currently valid OMB control number. 1. REPORT DATE 01 DEC 2008 2. REPORT

  9. Foreign Cooperation Fruitful for Sinopec

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    @@ On October 21, just the eve of Chinese President Jiang Zemin's visit to the United States, a total of 13 big-name enterprises in China and the United States signed five agreements in New York for cooperation in the petrochemical, telecom and energy fields with the contracted capital totaling US$4.7 billion. Of those deals, Sinopec Limited and ExxonMobil inked a framework agreement to beef up their bilateral strategic alliance and push ahead with their join venture projects developed in Southeast China's Guangdong Province and Fujian Province.

  10. Memetic Algorithm and its Application to the Arrangement of Exam Timetable

    Directory of Open Access Journals (Sweden)

    Wenhua Huang

    2016-06-01

    Full Text Available This paper looks at Memetic Algorithm for solving timetabling problems. We present a new memetic algorithm which consists of global search algorithm and local search algorithm. In the proposed method, a genetic algorithm is chosen for global search algorithm while a simulated annealing algorithm is used for local search algorithm. In particular, we could get an optimal solution through the .NET with the real data of JiangXi Normal University. Experimental results show that the proposed algorithm can solve the university exam timetabling problem efficiently.

  11. Reply to Comment on 'Diffusion of water and sodium counter-ions in nanopores of β-lactoglobulin crystal: a molecular simulation study'

    International Nuclear Information System (INIS)

    Malek, Kourosh; Coppens, Marc-Olivier

    2008-01-01

    The analysis in Hu and Jiang's Comment to our paper cannot reveal long-time diffusion, and incorrectly led the authors to conclude that the diffusion in beta-lactoglobuline is anomalous. In this context, the limitations of applying a mean-square displacement analysis to short, heterogeneous pore channels are discussed. A more appropriate approach based on first-passage time analysis is illustrated by a detailed analysis of water motion in a natural membrane protein channel. The partitioning and the motion of water molecules between core and surface hydration layers is discussed. Finally, the calculation of the water density profile is commented upon. (reply)

  12. Geochemical and Rheological Constraints on the Dynamics of the Oceanic Upper Mantle

    Science.gov (United States)

    2007-09-01

    this past year and I hope it continues for years to come. I thank my parents, Margaret and Colin , who have supported me in whatever I have 6 endeavored...et al., 1990; Drury et al., 1991; Jaroslow et al., 1996; Jin et al., 1998; Newman et al., 1999; Jiang et al., 2000). For the sample in Fig. 2. 1...plagioclase with decreasing pressure (e.g., Furusho and Kyuichi, 1999; Newman et al., 1999); see Drury et al. (1991 ) for a review of earlier literature

  13. Strengthening the R and D on fast reactor technology, and promoting its industrialization

    International Nuclear Information System (INIS)

    Wan Gang

    2008-01-01

    Based on the strategic thoughts of energy development in China expounded by Jiang Zemin in the article entitled 'Reflections on Energy Issues in China', the author points out in this paper that R and Ds on fast reactor technology shall be carried out timely in China by taking full advantage of international scientific resources, and overall planning in this regard shall be made as well. The point of view of strengthening fast reactor technology R and D and promoting its industrialization is also put forward in the paper. (authors)

  14. PALEONTOLOGY

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    <正>20072695 Hu Bin(Henan Polytechnic University,Jiaozuo,Henan 454003);Jiang Zaixing Trace Fossils of Deeper Lacustrine Deposits in the Paleogene Shahejie Formation of Jiyang Depression,Shandong Province,East China(Acta Palaeontologica Sinica,ISSN0001-6616,CN32-1188/Q,45(1),2006,p.83-94,1 illus.,2 plates,1 table,18 refs.)Key words:ichnofossils,Jiyang Depression The Paleogene Shahejie Formation of Jiyang Depression,Shandong Province,Eastern China,

  15. MATHEMATICS OF SENSING, EXPLOITATION, AND EXECUTION (MSEE) Sensing, Exploitation, and Execution (SEE) on a Foundation for Representation, Inference, and Learning

    Science.gov (United States)

    2016-07-01

    Automation (ICRA), 2016. [50]. Y. Lu, S.C. Zhu and Y.N. Wu, Learning FRAME Models Using CNN Filters, 30th AAAI Conference on Artificial Intelligence ...Method Cross-Subject Cross-View Cross-Environment Virtual View 0.507 0.478 0.274 Hankelet 0.542 0.452 0.286 Action Bank 0.246 0.176 N/A Poselet... Intelligence , vol. 34, no.7, 1354-1367, 2012. [3]. N. Jiang, W. Liu and Y. Wu, “Order Determination and Sparsity-Regularized Metric Learning for Adaptive

  16. Control of Flow Structure and Ignition of Hydrocarbon Fuel in Cavity and Behind Wallstep of Supersonic Duct by Filamentary DC Discharge

    Science.gov (United States)

    2011-01-01

    Lindstrom , K.R. Jackson, S. Williams, R. Givens, W.F. Bailey, C.J. Tam, W.F. Terry, AIAA Journal 47, 2368 (2009). 13. S.T. Sanders, J.A. Baldwin, T.P...A. Kuthi, C. Jiang, P. Ronney, and Martin A. Gundersen, ―Transient Plasma Ignition of Quiescent and Flowing Air/Fuel Mixtures‖ IEEE Transactions on...applications at elevated temperature. JQSRT 103 (2007) 565–577. 17. C.D. Lindstrom , K.R. Jackson, S. Williams, R. Givens, W.F. Bailey, C.J. Tam, W.F

  17. Highly sensitive photoassociation spectroscopy of ultracold 23Na133Cs molecular long-range states below the 3S 1/2 + 6P 3/2 limit

    Science.gov (United States)

    Liu, Yanyan; Wu, Jizhou; Liu, Wenliang; Wang, Xiaofeng; Wang, Wenhao; Ma, Jie; Xiao, Liantuan; Jia, Suotang

    2017-12-01

    Not Available Project supported by the National Key Research and Development Program of China (Grant No. 2017YFA0304203), the ChangJiang Scholars and Innovative Research Team in the University of the Ministry of Education of China (Grant No. IRT13076), the National Natural Science Foundation of China (Grant Nos. 91436108, 61378014, 61675121, 61705123, and 11434007), the Fund for Shanxi “1331 Project” Key Subjects Construction, China, and the Foundation for Outstanding Young Scholars of Shanxi Province, China (Grant No. 201601D021001).

  18. Enhancement of signal-to-noise ratio of ultracold polar NaCs molecular spectra by phase locking detection

    Science.gov (United States)

    Wang, Wenhao; Liu, Wenliang; Wu, Jizhou; Li, Yuqing; Wang, Xiaofeng; Liu, Yanyan; Ma, Jie; Xiao, Liantuan; Jia, Suotang

    2017-12-01

    Not Available Project supported by the National Key Research and Development Program of China (Grant No. 2017YFA0304203), the ChangJiang Scholars and Innovative Research Team in the University of the Ministry of Education of China (Grant No. IRT13076), the National Natural Science Foundation of China (Grant Nos. 91436108, 61378014, 61675121, 61705123, and 61722507), the Fund for Shanxi “1331 Project” Key Subjects Construction, China, and the Foundation for Outstanding Young Scholars of Shanxi Province, China (Grant No. 201601D021001).

  19. Electromagnetic Field Control and Optimization Using Metamaterials

    Science.gov (United States)

    2009-12-01

    Popović, and K. Hingerl. “Imperfect cloak- ing devices based on metamaterials,” Acta Physica Polonica A , 112(5):1083– 1088, 2007. 148 44. Jiang, Wei X...f. Jcpq Date Accepted: ... M ( A T~ 󈧢 S’t’P 2 GCt:f M. U. Thomas Date Dean, Graduate School of Engineering and Management APIT/DEE/ENG/09-13...dictated by the theory are inhomogeneous, anisotropic, and, in some instances, singular at various locations. In order for a cloak to be practically

  20. Developing Animal Models for Optimizing the Musculoskeletal Repair Potential of Emerging Human Progenitor Cell Therapies

    Science.gov (United States)

    2014-06-01

    into a central hub for group analysis and reporting. It is now being used for a just received R21 award to assess skeletal variation in a population...model to produce, and the use of the 3D X-rays the extent of deformity and the tempo of repair can be easily documented. Addition of the...Liu, Y., Boyd, N., Dennis, J., Jiang, X., Xin, X., Wang, L., Aguila, H., Rowe, D., Lichtler, A. and Goldberg , J. Developmental engineering of bone

  1. Protective effects of metformin on neointima formation in insulin resistance

    Directory of Open Access Journals (Sweden)

    Yu V Pankratova

    2013-06-01

    Full Text Available Реферат по материалам статьи Lu J, Ji J, Meng H, Wang D, Jiang B, Liu L, Randell E, Adeli K, Meng QH. The protective effect and underlying mechanism of metformin on neointima formation in fructose-induced insulin resistant rats. Cardiovasc Diabetol. 2013 Apr 5;12:58. doi: 10.1186/1475-2840-12-58.

  2. Biologically Inspired Materials for Electro-Responsive Coatings and the Photo-Oxidation of Water

    Science.gov (United States)

    2010-02-01

    from the 12-mer li - brary exhibited an over-expression of amide-containing amino acids. Both amides and hydrophilic residues can participate in hydrogen... li =17 73410 7865 [R(int) = 0.0350] 99.9 % Semi-empirical from equivalents 0.7216 and 0.5420 Full-matrix least-squares on F2 7865 / 27 / 442 1.058 R1...Joseph Wang, Gustavo Rivas, Mian Jiang, and Xueji Zhang. Electrochemically induced release of DNA from gold ultramicroelectrodes. Langmuir, 15:6541- 6545

  3. [Textual research on Chen Ye and his Jia cang jing yan fang (Family-preserved Empirical Recipes) of the Song Dynasty].

    Science.gov (United States)

    Zhang, Xuedan; Zhang, Ruqing; Chen, Dexing

    2014-01-01

    Chen Ye, an official of the Southern Song Dynasty, also known as Chen Rihua as his styled name, was born in Changle, Fuzhou in the reign of Shaoxing, and died during the reign of Duanping. He had been consecutively in the positions of Jiang shi lang (Court Gentleman for Ceremonial Service), Zhi zhou (Prefect) of Lingding, the Ti xing (Judicial Commissioner) of Guangdong, the Zong ling (Overseer-general) of Sichuan, Shan ding (Reviser), Shu lin and other positions in Tongzhou, Yuanzhou. His works included 1 volume of Gu ling xian sheng nian pu (Mr. Guling's Chronological Biography), 1 volume of Tan xie (On Humor), 1 volume of Shi hua (Poetry), 8 volumes of Jin yuan li shu (Jin Yuan's Smart Technique), 3 volumes of Yi jian zhi lei bian (Classified Compilation of Yijian's Annals), (Zeng guang) Suo sui lu (Augmented Records of Trivial Matters), 5 volumes of Jia cang jing yan fang (Family-preserved Empirical Recipes). He also compiled the 8-volume Yin jiang zhi (Yinjiang's Annals), published the 2-volume Jia cang ji yao fang (Collected Essential Recipes from Family Preservation), and other proses and poetry. Jia cang jing yan fang was a formulary compiled by Chen Ye, which was lost. Altogether 74 of its recipes were cited in Fu ren da quan liang fang (Complete Effective Prescriptions for Women's Diseases), Shou qin yang lao shu (A Book for Pursuing Seniors' Longevity and Healthcare), Pu ji fang (Prescriptions for Universal Relief) and Yong le da dian (Yongle Encyclopedia).

  4. Memory under pressure: secondary-task effects on contextual cueing of visual search.

    Science.gov (United States)

    Annac, Efsun; Manginelli, Angela A; Pollmann, Stefan; Shi, Zhuanghua; Müller, Hermann J; Geyer, Thomas

    2013-11-04

    Repeated display configurations improve visual search. Recently, the question has arisen whether this contextual cueing effect (Chun & Jiang, 1998) is itself mediated by attention, both in terms of selectivity and processing resources deployed. While it is accepted that selective attention modulates contextual cueing (Jiang & Leung, 2005), there is an ongoing debate whether the cueing effect is affected by a secondary working memory (WM) task, specifically at which stage WM influences the cueing effect: the acquisition of configural associations (e.g., Travis, Mattingley, & Dux, 2013) versus the expression of learned associations (e.g., Manginelli, Langer, Klose, & Pollmann, 2013). The present study re-investigated this issue. Observers performed a visual search in combination with a spatial WM task. The latter was applied on either early or late search trials--so as to examine whether WM load hampers the acquisition of or retrieval from contextual memory. Additionally, the WM and search tasks were performed either temporally in parallel or in succession--so as to permit the effects of spatial WM load to be dissociated from those of executive load. The secondary WM task was found to affect cueing in late, but not early, experimental trials--though only when the search and WM tasks were performed in parallel. This pattern suggests that contextual cueing involves a spatial WM resource, with spatial WM providing a workspace linking the current search array with configural long-term memory; as a result, occupying this workspace by a secondary WM task hampers the expression of learned configural associations.

  5. On the limits of statistical learning: Intertrial contextual cueing is confined to temporally close contingencies.

    Science.gov (United States)

    Thomas, Cyril; Didierjean, André; Maquestiaux, François; Goujon, Annabelle

    2018-04-12

    Since the seminal study by Chun and Jiang (Cognitive Psychology, 36, 28-71, 1998), a large body of research based on the contextual-cueing paradigm has shown that the cognitive system is capable of extracting statistical contingencies from visual environments. Most of these studies have focused on how individuals learn regularities found within an intratrial temporal window: A context predicts the target position within a given trial. However, Ono, Jiang, and Kawahara (Journal of Experimental Psychology, 31, 703-712, 2005) provided evidence of an intertrial implicit-learning effect when a distractor configuration in preceding trials N - 1 predicted the target location in trials N. The aim of the present study was to gain further insight into this effect by examining whether it occurs when predictive relationships are impeded by interfering task-relevant noise (Experiments 2 and 3) or by a long delay (Experiments 1, 4, and 5). Our results replicated the intertrial contextual-cueing effect, which occurred in the condition of temporally close contingencies. However, there was no evidence of integration across long-range spatiotemporal contingencies, suggesting a temporal limitation of statistical learning.

  6. [The different experession of human papilloma viral types 6 and 11 in Uyghur and Chinese juvenile recurrent respiratory papillomatosis in a large pediatric population in Xinjiang].

    Science.gov (United States)

    Zainura, Amrulla; Yalkun, Yasin; Wu, Mei

    2013-11-01

    To investigate the Human papilloma viral types 6 and 11 in a large pediatric population in XinJiang and the different expression in chinese and uyghur pediatric population. Using polymerase chain reaction (PCR), we analyzed paraffin embedded tissue in 42 cases of juvenile Recurrent Respiratory Papillomatosis (JRRP)and determined the HPV types 6 and 11, and to correlate these results with retrospectively analysis about those cases who were consecutively treated in our ENT department, meanwhile we carry out a critical review of the literature of JRRP. A total HPV infection positive rate was 97.61% (41/42), and HPV11 positive rate was 63.41% (41/26), HPV6 positive rate was 36.58% (41/15). In uyghur patient HPV11 positive rate was 65.38% (17/26), HPV6 positive rate was53. 33% (8/15). in Chince patient HPV11 positive rate was 34.61% (9/26), HPV6 positive rate was 46.67% (7/15). Juvenile laryngeal papilloma is associated with HPV11, HPV6 infection and we considered that HPV11 infection may be the important guideline of the evaluation of disease prognosis. but no statistical signtificance was determined in the patients of various ethnic groups in Xin jiang (P > 0.05).

  7. Prey perception in feeding-current feeding copepods

    DEFF Research Database (Denmark)

    Kiørboe, Thomas; Goncalves, Rodrigo J.; Florian Couespel, Damien

    2016-01-01

    We reply to the comments of Paffenhöfer and Jiang () who argues that remote chemical prey perception is necessary for feeding-current feeding copepods to fulfill their nutritional requirements in a dilute ocean, that remote chemical prey detection may only be observed at very low prey concentrati......We reply to the comments of Paffenhöfer and Jiang () who argues that remote chemical prey perception is necessary for feeding-current feeding copepods to fulfill their nutritional requirements in a dilute ocean, that remote chemical prey detection may only be observed at very low prey...... cells have short intense leakage burst, only a very small fraction of prey cells would be available to the copepod at any instance in time and, thus would be inefficient at low prey concentration. Finally, we report a few new observations of prey capture in two species of copepods, Temora longicornis...... and Centropages hamatus, offered a 45-μm sized dinoflagellate at very low concentration. The observed short prey detection distances, up to a few prey cell radii, are consistent with mechanoreception and we argue briefly that near-field mechanoreception is the most likely and common prey perception mechanism...

  8. Numerical study on the convergence to steady state solutions of a new class of high order WENO schemes

    Science.gov (United States)

    Zhu, Jun; Shu, Chi-Wang

    2017-11-01

    A new class of high order weighted essentially non-oscillatory (WENO) schemes (Zhu and Qiu, 2016, [50]) is applied to solve Euler equations with steady state solutions. It is known that the classical WENO schemes (Jiang and Shu, 1996, [23]) might suffer from slight post-shock oscillations. Even though such post-shock oscillations are small enough in magnitude and do not visually affect the essentially non-oscillatory property, they are truly responsible for the residue to hang at a truncation error level instead of converging to machine zero. With the application of this new class of WENO schemes, such slight post-shock oscillations are essentially removed and the residue can settle down to machine zero in steady state simulations. This new class of WENO schemes uses a convex combination of a quartic polynomial with two linear polynomials on unequal size spatial stencils in one dimension and is extended to two dimensions in a dimension-by-dimension fashion. By doing so, such WENO schemes use the same information as the classical WENO schemes in Jiang and Shu (1996) [23] and yield the same formal order of accuracy in smooth regions, yet they could converge to steady state solutions with very tiny residue close to machine zero for our extensive list of test problems including shocks, contact discontinuities, rarefaction waves or their interactions, and with these complex waves passing through the boundaries of the computational domain.

  9. Preventing and controlling land subsidence in Shanghai -towards more integrated and effective land use and ground water governance in the Yangtze Delta

    Science.gov (United States)

    Dai, Liping

    2016-04-01

    The Yangtze Delta, covers 210,700 square kilometers and with 156 million inhabitants (NRDC, 2010; The National Bureau of Statistics, 2011), is one of the areas most severely affected by land subsidence in China. Up to 2012, the area with cumulative subsidence above 200 mm in Yangtze Delta has been closed to 10,000 square kilometers. Shanghai, located at the estuary of the Yangtze River and with a population of 23 million, is the most densely populated city in Yangtze Delta (The National Bureau of Statistics, 2011). Since 1921, the recorded cumulative subsidence has been 200 to 300 mm in the central area of the city (Chai, Shen, Zhu, & Zhang, 2005). Excessive pumping of groundwater is considered to be the leading reason, accounts for nearly 70%, of the city's land subsidence, the weight of skyscrapers and global warming also play hefty roles (30%) (Springer, 2012). Research has shown that the main method to control land subsidence in Shanghai is to prevent groundwater from dropping (Chai, Shen, Zhu, & Zhang, 2005), the city has made great efforts in this regard since 1965 (the beginning of the so-called "control period"), for example, it has been recharging underground water through 121 wells with more than 60,000 tons every day since 2012 (Chinadaily, 2012). It is a huge burden considering the city has been suffering from a shortage of fresh water. In 2013, with the other two provinces of Jiangsu and Zhejiang in Yangtze Delta, Shanghai signed a delta cooperation agreement on the prevention and control of land subsidence and jointly issued a Prevention and Control Planning on Land Subsidence in Yangtze Delta (2014-2020), which aims to establish a long-effect mechanism in the delta scope. This research aims to analyze and assess the land and groundwater governance arrangements related to land subsidence in the Yangtze Delta in general and Shanghai in specific, in order to develop optimizing adaptation strategies and associated governance arrangements. It examines the

  10. Herb-drug interactions.

    Science.gov (United States)

    Fugh-Berman, A

    2000-01-08

    Concurrent use of herbs may mimic, magnify, or oppose the effect of drugs. Plausible cases of herb-drug interactions include: bleeding when warfarin is combined with ginkgo (Ginkgo biloba), garlic (Allium sativum), dong quai (Angelica sinensis), or danshen (Salvia miltiorrhiza); mild serotonin syndrome in patients who mix St John's wort (Hypericum perforatum) with serotonin-reuptake inhibitors; decreased bioavailability of digoxin, theophylline, cyclosporin, and phenprocoumon when these drugs are combined with St John's wort; induction of mania in depressed patients who mix antidepressants and Panax ginseng; exacerbation of extrapyramidal effects with neuroleptic drugs and betel nut (Areca catechu); increased risk of hypertension when tricyclic antidepressants are combined with yohimbine (Pausinystalia yohimbe); potentiation of oral and topical corticosteroids by liquorice (Glycyrrhiza glabra); decreased blood concentrations of prednisolone when taken with the Chinese herbal product xaio chai hu tang (sho-salko-to); and decreased concentrations of phenytoin when combined with the Ayurvedic syrup shankhapushpi. Anthranoid-containing plants (including senna [Cassia senna] and cascara [Rhamnus purshiana]) and soluble fibres (including guar gum and psyllium) can decrease the absorption of drugs. Many reports of herb-drug interactions are sketchy and lack laboratory analysis of suspect preparations. Health-care practitioners should caution patients against mixing herbs and pharmaceutical drugs.

  11. Effective treatment with icotinib in lung adenocarcinoma with EGFR and ALK co-alterations and brain metastasis

    Directory of Open Access Journals (Sweden)

    Ye CY

    2016-10-01

    Full Text Available Chenyang Ye,1,* Ji Wang,2,* Shu Zheng,1 Ying Chai3 1Cancer Institute, Key Laboratory of Cancer Prevention and Intervention, National Ministry of Education, Provincial Key Laboratory of Molecular Biology in Medical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, 2Department of Surgical Oncology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, 3Department of Thoracic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China *These authors contributed equally to this work Abstract: We report a rare case of advanced lung cancer with epidermal growth factor receptor and anaplastic lymphoma kinase co-alterations and brain metastasis, in which icotinib treatment was effective for both the primary lung tumor and the brain metastasis. The patient achieved important clinical remission with a progression-free survival for two years. Our treatment strategy appears to be a promising therapeutic approach for this subgroup of patients. Keywords: lung cancer, brain metastasis, EGFR, ALK, icotinib

  12. Preparation of a nano- and micro-fibrous decellularized scaffold seeded with autologous mesenchymal stem cells for inguinal hernia repair

    Directory of Open Access Journals (Sweden)

    Zhang Y

    2017-02-01

    Full Text Available Yinlong Zhang,1,* Yuanyuan Zhou,1,* Xu Zhou,2,* Bin Zhao,1,* Jie Chai,1 Hongyi Liu,1 Yifei Zheng,1 Jinling Wang,3 Yaozong Wang,4 Yilin Zhao2 1Medical College, Xiamen University, 2Department of Oncology and Vascular Intervention Radiology, 3Department of Emergency, 4Department of Orthopaedics, Zhongshan Hospital, Xiamen University, Xiamen, People’s Republic of China *These authors contributed equally to this work Abstract: Prosthetic meshes used for hernioplasty are usually complicated with chronic pain due to avascular fibrotic scar or mesh shrinkage. In this study, we developed a tissue-engineered mesh (TEM by seeding autologous bone marrow-derived mesenchymal stem cells onto nanosized fibers decellularized aorta (DA. DA was achieved by decellularizing the aorta sample sequentially with physical, mechanical, biological enzymatic digestion, and chemical detergent processes. The tertiary structure of DA was constituted with micro-, submicro-, and nanosized fibers, and the original strength of fresh aorta was retained. Inguinal hernia rabbit models were treated with TEMs or acellular meshes (AMs. After implantation, TEM-treated rabbit models showed no hernia recurrence, whereas AM-treated animals displayed bulges in inguinal area. At harvest, TEMs were thicker, have less adhesion, and have stronger mechanical strength compared to AMs (P<0.05. Moreover, TEM showed better cell infiltration, tissue regeneration, and neovascularization (P<0.05. Therefore, these cell-seeded DAs with nanosized fibers have potential for use in inguinal hernioplasty. Keywords: nanobiomaterial, tissue engineering, inguinal hernia, hernioplasty, decellularized aorta 

  13. Can Medical Herbs Stimulate Regeneration or Neuroprotection and Treat Neuropathic Pain in Chemotherapy-Induced Peripheral Neuropathy?

    Directory of Open Access Journals (Sweden)

    Sven Schröder

    2013-01-01

    Full Text Available Chemotherapy-induced neuropathy (CIPN has a relevant impact on the quality of life of cancer patients. There are no curative conventional treatments, so further options have to be investigated. We conducted a systematic review in English and Chinese language databases to illuminate the role of medical herbs. 26 relevant studies on 5 single herbs, one extract, one receptor-agonist, and 8 combinations of herbs were identified focusing on the single herbs Acorus calamus rhizoma, Cannabis sativa fructus, Chamomilla matricaria, Ginkgo biloba, Salvia officinalis, Sweet bee venom, Fritillaria cirrhosae bulbus, and the herbal combinations Bu Yang Huan Wu, modified Bu Yang Huan Wu plus Liuwei Di Huang, modified Chai Hu Long Gu Mu Li Wan, Geranii herba plus Aconiti lateralis praeparata radix , Niu Che Sen Qi Wan (Goshajinkigan, Gui Zhi Jia Shu Fu Tang (Keishikajutsubuto, Huang Qi Wu Wu Tang (Ogikeishigomotsuto, and Shao Yao Gan Cao Tang (Shakuyakukanzoto. The knowledge of mechanism of action is still limited, the quality of clinical trials needs further improvement, and studies have not yielded enough evidence to establish a standard practice, but a lot of promising substances have been identified. While CIPN has multiple mechanisms of neuronal degeneration, a combination of herbs or substances might deal with multiple targets for the aim of neuroprotection or neuroregeneration in CIPN.

  14. Retracted: Molecular Characterization and Biological Activity of Interferon-α in Indian Peafowl (Pavo cristatus).

    Science.gov (United States)

    Zhao, Hongjing; Wang, Yu; Liu, Juanjuan; Shao, Yizhi; Li, Jinglun; Chai, Hongliang; Xing, Mingwei

    2017-08-07

    DNA and Cell Biology (DNA&CB) is officially retracting the paper by Zhao H, Wang Y, Liu J, Shao Y, Li J, Chai H, Xing M, entitled, "Molecular Characterization and Biological activity of Interferon-α in Indian Peafowl (Pavo cristatus)," [Epub ahead of print]; 2017, DOI: 10.1089/dna.2017.3798. The Editor-in-Chief of DNA&CB, Dr. Carol Shoshkes Reiss, was alerted to a discrepancy between the findings in the article by Zhao et al., and those of others, about the absence of expression of ISG15 in chickens. Dr. Reiss requested from the authors a clarification in their observations and inquired about the failure to include relevant citations in the reference section of the paper. Based on the response from the authors, it appeared that they did not have the confidence in the data as they were not able to repeat the experiments, and were also unsure of the molecular probes that were used in the study. Therefore, the Editor has determined that the paper should be officially retracted from DNA and Cell Biology.

  15. Do national drug policies influence antiretroviral drug prices? Evidence from the Southern African Development community.

    Science.gov (United States)

    Liu, Yao; Galárraga, Omar

    2017-03-01

    The efficacy of low- and middle-income countries’ (LMIC) national drug policies in managing antiretroviral (ARV) pharmaceutical prices is not well understood. Though ARV drug prices have been declining in LMIC over the past decade, little research has been done on the role of their national drug policies. This study aims to (i) analyse global ARV prices from 2004 to 2013 and (ii) examine the relationship of national drug policies to ARV prices. Analysis of ARV drug prices utilized data from the Global Price Reporting Mechanism from the World Health Organization (WHO). Ten of the most common ARV drugs (first-line and second-line) were selected. National drug policies were also assessed for 12 countries in the South African Development Community (SADC), which self-reported their policies through WHO surveys. The best predictor of ARV drug price was generic status—the generic versions of 8 out of 10 ARV drugs were priced lower than branded versions. However, other factors such as transaction volume, HIV prevalence, national drug policies and PEPFAR/CHAI involvement were either not associated with ARV drug price or were not consistent predictors of price across different ARV drugs. In the context of emerging international trade agreements, which aim to strengthen patent protections internationally and potentially delay the sale of generic drugs in LMIC, this study shines a spotlight on the importance of generic drugs in controlling ARV prices. Further research is needed to understand the impact of national drug policies on ARV prices.

  16. Néron models and base change

    CERN Document Server

    Halle, Lars Halvard

    2016-01-01

    Presenting the first systematic treatment of the behavior of Néron models under ramified base change, this book can be read as an introduction to various subtle invariants and constructions related to Néron models of semi-abelian varieties, motivated by concrete research problems and complemented with explicit examples. Néron models of abelian and semi-abelian varieties have become an indispensable tool in algebraic and arithmetic geometry since Néron introduced them in his seminal 1964 paper. Applications range from the theory of heights in Diophantine geometry to Hodge theory. We focus specifically on Néron component groups, Edixhoven’s filtration and the base change conductor of Chai and Yu, and we study these invariants using various techniques such as models of curves, sheaves on Grothendieck sites and non-archimedean uniformization. We then apply our results to the study of motivic zeta functions of abelian varieties. The final chapter contains a list of challenging open questions. This book is a...

  17. Leaflet manual of external beam radiation therapy for hepatocellular carcinoma: a review of the indications, evidences, and clinical trials

    Directory of Open Access Journals (Sweden)

    Rim CH

    2018-05-01

    Full Text Available Chai Hong Rim, Won Sup Yoon Department of Radiation Oncology, Ansan Hospital, Korea University Medical College, Ansan, Republic of Korea Abstract: The use of external beam radiation therapy (EBRT in the treatment of hepatocellular carcinoma (HCC, which was rarely performed due to liver toxicity with a previous technique, has increased. Palliation of portal vein thrombosis, supplementation for insufficient transarterial chemoembolization, and provision of new curative opportunities using stereotactic body radiotherapy are the potential indications for use of EBRT. The mechanism of EBRT treatment, with its radiobiological and physical perspectives, differs from those of conventional medical treatment or surgery. Therefore, understanding the effects of EBRT may be unfamiliar to physicians other than radiation oncologists, especially in the field of HCC, where EBRT has recently begun to be applied. The first objective of this review was to concisely explain the indications for use of EBRT for HCC for all physicians treating HCC. Therefore, this review focuses on the therapeutic outcomes rather than the detailed biological and physical background. We also reviewed recent clinical trials that may extend the indications for use of EBRT. Finally, we reviewed the current clinical practice guidelines for the treatment of HCC and discuss the current recommendations and future perspectives. Keywords: hepatocellular carcinoma, liver neoplasm, external beam radiotherapy, stereotactic body radiotherapy, clinical trials, sorafenib, guidelines

  18. Effect of amino acid ligands on the structure of iron porphyrins and their ability to bind oxygen.

    Science.gov (United States)

    Berryman, Victoria E J; Baker, Matthew G; Boyd, Russell J

    2014-06-26

    Density functional theory is used to study a series of model iron porphyrins in the gas phase. In the first part of this study, three range-separated hybrid density functionals developed by Chai and Head-Gordon were assessed; ωB97, ωB97X, and ωB97XD. The effects of including full Hartree-Fock exchange at long-range and dispersion corrections are reported with respect to the geometries and binding energies of oxygen to the iron porphyrin systems. The functionals all correctly predict the quintet ground state for the deoxy-iron porphyrins, where typically hybrid functionals fail and predict a triplet ground state. Including dispersion in ωB97XD is shown to give the best results for the O2 binding energy and geometrical parameters. The second part of the study employs ωB97XD to study iron porphine systems with different amino acids in the axial position. Geometrical parameters are reported and compared to experimental data, where available. Binding energies of the systems with oxygen are also reported and discussed.

  19. Role of exact exchange in thermally-assisted-occupation density functional theory: A proposal of new hybrid schemes.

    Science.gov (United States)

    Chai, Jeng-Da

    2017-01-28

    We propose hybrid schemes incorporating exact exchange into thermally assisted-occupation-density functional theory (TAO-DFT) [J.-D. Chai, J. Chem. Phys. 136, 154104 (2012)] for an improved description of nonlocal exchange effects. With a few simple modifications, global and range-separated hybrid functionals in Kohn-Sham density functional theory (KS-DFT) can be combined seamlessly with TAO-DFT. In comparison with global hybrid functionals in KS-DFT, the resulting global hybrid functionals in TAO-DFT yield promising performance for systems with strong static correlation effects (e.g., the dissociation of H 2 and N 2 , twisted ethylene, and electronic properties of linear acenes), while maintaining similar performance for systems without strong static correlation effects. Besides, a reasonably accurate description of noncovalent interactions can be efficiently achieved through the inclusion of dispersion corrections in hybrid TAO-DFT. Relative to semilocal density functionals in TAO-DFT, global hybrid functionals in TAO-DFT are generally superior in performance for a wide range of applications, such as thermochemistry, kinetics, reaction energies, and optimized geometries.

  20. A Network-Based Pharmacology Study of the Herb-Induced Liver Injury Potential of Traditional Hepatoprotective Chinese Herbal Medicines.

    Science.gov (United States)

    Hong, Ming; Li, Sha; Tan, Hor Yue; Cheung, Fan; Wang, Ning; Huang, Jihan; Feng, Yibin

    2017-04-14

    Herbal medicines are widely used for treating liver diseases and generally regarded as safe due to their extensive use in Traditional Chinese Medicine practice for thousands of years. However, in recent years, there have been increased concerns regarding the long-term risk of Herb-Induced Liver Injury (HILI) in patients with liver dysfunction. Herein, two representative Chinese herbal medicines: one-Xiao-Chai-Hu-Tang (XCHT)-a composite formula, and the other- Radix Polygoni Multiflori (Heshouwu) -a single herb, were analyzed by network pharmacology study. Based on the network pharmacology framework, we exploited the potential HILI effects of XCHT and Heshouwu by predicting the molecular mechanisms of HILI and identified the potential hepatotoxic ingredients in XCHT and Heshouwu . According to our network results, kaempferol and thymol in XCHT and rhein in Heshouwu exhibit the largest number of liver injury target connections, whereby CASP3, PPARG and MCL1 may be potential liver injury targets for these herbal medicines. This network pharmacology assay might serve as a useful tool to explore the underlying molecular mechanism of HILI. Based on the theoretical predictions, further experimental verification should be performed to validate the accuracy of the predicted interactions between herbal ingredients and protein targets in the future.

  1. Thermal decomposition kinetics of sorghum straw via thermogravimetric analysis.

    Science.gov (United States)

    Dhyani, Vaibhav; Kumar, Jitendra; Bhaskar, Thallada

    2017-12-01

    The thermal decomposition of sorghum straw was investigated by non-isothermal thermogravimetric analysis, where the determination of kinetic triplet (activation energy, pre-exponential factor, and reaction model), was the key objective. The activation energy was determined using different isoconversional methods: Friedman, Flynn-Wall-Ozawa (FWO), Kissinger-Akahira-Sunose (KAS), Starink, Iterative method of Chai & Chen, Vyazovkin AIC method, and Li & Tang equation. The pre-exponential factor was calculated using Kissinger's equation; while the reaction model was predicted by comparison of z-master plot obtained from experimental values with the theoretical plots. The values of activation energy obtained from isoconversional methods were further used for evaluation of thermodynamic parameters, enthalpy, entropy and Gibbs free energy. Results showed three zones of pyrolysis having average activation energy values of 151.21kJ/mol, 116.15kJ/mol, and 136.65kJ/mol respectively. The data was well fitting with two-dimension 'Valensi' model for conversion values from 0 to 0.4 with a coefficient of determination (R 2 ) value of 0.988, and with third order reaction model for values from 0.4 to 0.9 with an R 2 value of 0.843. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Performance Evaluation of Linear (ARMA and Threshold Nonlinear (TAR Time Series Models in Daily River Flow Modeling (Case Study: Upstream Basin Rivers of Zarrineh Roud Dam

    Directory of Open Access Journals (Sweden)

    Farshad Fathian

    2017-01-01

    Full Text Available Introduction: Time series models are generally categorized as a data-driven method or mathematically-based method. These models are known as one of the most important tools in modeling and forecasting of hydrological processes, which are used to design and scientific management of water resources projects. On the other hand, a better understanding of the river flow process is vital for appropriate streamflow modeling and forecasting. One of the main concerns of hydrological time series modeling is whether the hydrologic variable is governed by the linear or nonlinear models through time. Although the linear time series models have been widely applied in hydrology research, there has been some recent increasing interest in the application of nonlinear time series approaches. The threshold autoregressive (TAR method is frequently applied in modeling the mean (first order moment of financial and economic time series. Thise type of the model has not received considerable attention yet from the hydrological community. The main purposes of this paper are to analyze and to discuss stochastic modeling of daily river flow time series of the study area using linear (such as ARMA: autoregressive integrated moving average and non-linear (such as two- and three- regime TAR models. Material and Methods: The study area has constituted itself of four sub-basins namely, Saghez Chai, Jighato Chai, Khorkhoreh Chai and Sarogh Chai from west to east, respectively, which discharge water into the Zarrineh Roud dam reservoir. River flow time series of 6 hydro-gauge stations located on upstream basin rivers of Zarrineh Roud dam (located in the southern part of Urmia Lake basin were considered to model purposes. All the data series used here to start from January 1, 1997, and ends until December 31, 2011. In this study, the daily river flow data from January 01 1997 to December 31 2009 (13 years were chosen for calibration and data for January 01 2010 to December 31 2011

  3. WE, THE ONES FROM MAKULUSU AND JOSÉ LUANDINO VIEIRA’S UTOPIC PERSPECTIVE

    Directory of Open Access Journals (Sweden)

    Leila de Almeida Barros Silvana

    2013-11-01

    Full Text Available The definitions of tradition as an ongoing process, on the one hand, and modernity as rupture, on the other, are nowadays social optical illusions (BALANDIER, 1976. The continuous confrontation established between the maintaining factors of a popular culture and knowledge and the chai­ned disruptions brought by progress generate a third type of sociocultu­ral system, eminently unstable, that emerges within post-colonial societies. As a space determinant of identity construction, this new world engenders wandering individuals. For the Angolan writer José Luandino Vieira, the utopian dream of an Angolan nation free from the shackles of the colonial power is precisely the result of a sum between the traditional knowledge and that knowledge which is gained from the experience of modernity. Based on the notions of tradition and modernity presented in As Dinâmicas Sociais, by Georges Balandier (1976, and O discurso filosófico da modernidade, by Jürgen Habermas (2000, this study aims at understanding how the utopian perspective of Luandino Vieira (1974 is revealed on the novel Nós, os do Makulusu. It analyzes the figure of the narrator (Mais-Velho, who wanders by the streets of Luanda led by the time of war and cut off by the filters of his memory. Here, past, present and future are diluted to encompass in this narrative structure, simultaneously, tradition and modernity.

  4. 中西方古典音乐放松效果及生理唤醒对比——莫扎特D大调双钢琴奏鸣曲K.448与春江花月夜曲%On the Comparison of Perceived and Physiological Indicators of Relaxation of Chinese and Western Classical Music

    Institute of Scientific and Technical Information of China (English)

    李哲; 汤永隆; 邓丽俐; 赵玉芳

    2009-01-01

    以33名大学本科生为实验对象,随机安排在10 min的莫扎特奏鸣曲K.448、春江花月夜曲或无音乐条件中,被试在实验前后自评其放松效果,记录其心率、皮温、皮电生理指标.结果表明:在清醒、注意和心率上,音乐类型和测量时间的交互作用显著;莫扎特音乐组在清醒、注意和心率均呈上升趋势,而另两组呈下降趋势;春江花月夜组心率显著下降,放松增加感高于其他两组;其他指标无显著差异.%The research conducted a comparison of the subjective and objective indicators of relaxation under Western classical music and Chinese classical music backgrounds. Thirty-three undergraduate students were randomly assigned to listen to one of two relaxation ("Mozart Sonata for Two Pianos in D Major-K. 448" or "Chun Jiang Hua Yue Ye") or control (silence) conditions for 10 minutes. The students' self-reports of arousal, attention, mood, and relaxation before and after exposure to the music condition, and records of HR, TEMP and SC biofeedback were obtained. By using MANOVA to analyze data in different music backgrounds and different experimental phases, the results indicated that arousal, attention and HR of participants showed significant interaction between music type and experimental phases. Participants' arousal, attention and HR in Mozart group have a greater increase than other two groups. In Chun Jiang Hua Yue Ye group, participants" HR has a significant greater decrease; the relaxation in Chun Jiang Hua Yue Ye group was the highest among three groups. However, no differences were found between different types of music on mood, SC and TEMP. To Chinese people, Chinese classical music has more relaxation effect than Western classical music.

  5. Reconstructing the spatial pattern of historical forest land in China in the past 300 years

    Science.gov (United States)

    Yang, Xuhong; Jin, Xiaobin; Xiang, Xiaomin; Fan, Yeting; Shan, Wei; Zhou, Yinkang

    2018-06-01

    The reconstruction of the historical forest spatial distribution is of a great significance to understanding land surface cover in historical periods as well as its climate and ecological effects. Based on the maximum scope of historical forest land before human intervention, the characteristics of human behaviors in farmland reclamation and deforestation for heating and timber, we create a spatial evolution model to reconstruct the spatial pattern of historical forest land. The model integrates the land suitability for reclamation, the difficulty of deforestation, the attractiveness of timber trading markets and the abundance of forest resources to calibrate the potential scope of historical forest land with the rationale that the higher the probability of deforestation for reclamation and wood, the greater the likelihood that the forest land will be deforested. Compared to the satellite-based forest land distribution in 2000, about 78.5% of our reconstructed historical forest grids are of the absolute error between 25% and -25% while as many as 95.85% of those grids are of the absolute error between 50% and -50%, which indirectly validates the feasibility of our reconstructed model. Then, we simulate the spatial distribution of forest land in China in 1661, 1724, 1820, 1887, 1933 and 1952 with the grid resolution of 1 km × 1 km. Our result shows that (1) the reconstructed historical forest land in China in the past 300 years concentrates in DaXingAnLing, XiaoXingAnLing, ChangBaiShan, HengDuanShan, DaBaShan, WuYiShan, DaBieShan, XueFengShang and etc.; (2) in terms of the spatial evolution, historical forest land shrank gradually in LiaoHe plains, SongHuaJiang-NenJiang plains and SanJiang plains of eastnorth of China, Sichuan basins and YunNan-GuiZhou Plateaus; and (3) these observations are consistent to the proceeding of agriculture reclamation in China in past 300 years towards Northeast China and Southwest China.

  6. Data on fossil fuel availability for Shared Socioeconomic Pathways

    Directory of Open Access Journals (Sweden)

    Nico Bauer

    2017-02-01

    Full Text Available The data files contain the assumptions and results for the construction of cumulative availability curves for coal, oil and gas for the five Shared Socioeconomic Pathways. The files include the maximum availability (also known as cumulative extraction cost curves and the assumptions that are applied to construct the SSPs. The data is differentiated into twenty regions. The resulting cumulative availability curves are plotted and the aggregate data as well as cumulative availability curves are compared across SSPs. The methodology, the data sources and the assumptions are documented in a related article (N. Bauer, J. Hilaire, R.J. Brecha, J. Edmonds, K. Jiang, E. Kriegler, H.-H. Rogner, F. Sferra, 2016 [1] under DOI: http://dx.doi.org/10.1016/j.energy.2016.05.088.

  7. Lanthanide metal-organic frameworks

    International Nuclear Information System (INIS)

    Cheng, Peng

    2015-01-01

    This book contains the following nine chapters: lanthanide metal-organic frameworks: syntheses, properties, and potential applications (Stephen Fordham, Xuan Wang, Mathieu Bosch, Hong-Cai Zhou); 2. chiral lanthanide metal-organic frameworks (Weisheng Liu, Xiaoliang Tang); 3. Porous lanthanide metal-organic frameworks for gas storage and separation (Bin Li, Banglin Chen); 4. Luminescent lanthanide metal-organic frameworks (Xue-Zhi Song, Shu-Yan Song, Hong-Jie Zhang); 5. Metal-organic frameworks based on lanthanide clusters (Lian Chen, Feilong Jiang, Kang Zhou, Mingyan Wu, Maochun Hong); 6. metal-organic frameworks with d-f cyanide bridges: structural diversity, bonding regime, and magnetism (Marilena Ferbinteanu, Fanica Cimpoesu, Stefania Tanase); 7. transition-lanthanide heterometal-organic frameworks: synthesis, structures, and properties (Wei Shi, Ke Liu, Peng Cheng); 8: MOFs of uranium and the actinides (Juan Su, Jiesheng Chen); 9. Nanostructured and/or nanoscale lanthanide metal-organic frameworks (Zhonghao Zhang, Zhiping Zheng).

  8. First results of the TIANSHAN radio experiment for neutrino detection

    Energy Technology Data Exchange (ETDEWEB)

    Martineau-Huynh, O., E-mail: omartino@in2p3.fr [Laboratoire de Physique Nucleaire et de Physique des Hautes Energies, CNRS/IN2P3 and Universite Pierre et Marie Curie, Paris Cedex (France); National Astronomical Observatories, Chinese Academy of Science, Beijing (China); Key Laboratory of Particle Astrophysics, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing (China); Ardouin, D. [SUBATECH, Ecole des Mines, CNRS/IN2P3 and Universite de Nantes, Nantes (France); Carloganu, C. [Clermont Universite, Universite Blaise Pascal, CNRS/IN2P3, Laboratoire de Physique Corpusculaire, BP 10448, Clermond-Ferrand (France); Charrier, D. [SUBATECH, Ecole des Mines, CNRS/IN2P3 and Universite de Nantes, Nantes (France); Gou, Q.; Hu, H. [Key Laboratory of Particle Astrophysics, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing (China); Kai, L. [Graduate University of Chinese Academy of Science, Beijing 100049 (China); Lautridou, P. [SUBATECH, Ecole des Mines, CNRS/IN2P3 and Universite de Nantes, Nantes (France); Niess, V. [Clermont Universite, Universite Blaise Pascal, CNRS/IN2P3, Laboratoire de Physique Corpusculaire, BP 10448, Clermond-Ferrand (France); Ravel, O. [SUBATECH, Ecole des Mines, CNRS/IN2P3 and Universite de Nantes, Nantes (France); Saugrin, T.; Wu, X. [National Astronomical Observatories, Chinese Academy of Science, Beijing (China); Zhang, J.; Zhang, Y. [Key Laboratory of Particle Astrophysics, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing (China); Zhao, M. [National Astronomical Observatories, Chinese Academy of Science, Beijing (China); Zheng, Y. [Graduate University of Chinese Academy of Science, Beijing 100049 (China)

    2012-01-11

    We present the first results of a set-up called TIANSHAN radio experiment for neutrino detection (TREND) being presently deployed on the site of the 21 cm array (21CMA) radio telescope, in XinJiang, China. We describe here its detection performances as well as the analysis method we applied to the data recorded with a small scale prototype. We demonstrate the ability of the TREND set-up for an autonomous radio-detection of extended air showers induced by cosmic rays. The full set-up will consist of 80 antennas deployed over a 4 km{sup 2} area, and could result in a very attractive and unequalled radio-detection facility for the characterization of showers induced by ultra-high energy neutrinos with energies around 10{sup 17} eV.

  9. Regularity of C*-algebras and central sequence algebras

    DEFF Research Database (Denmark)

    Christensen, Martin S.

    The main topic of this thesis is regularity properties of C*-algebras and how these regularity properties are re ected in their associated central sequence algebras. The thesis consists of an introduction followed by four papers [A], [B], [C], [D]. In [A], we show that for the class of simple...... Villadsen algebra of either the rst type with seed space a nite dimensional CW complex, or the second type, tensorial absorption of the Jiang-Su algebra is characterized by the absence of characters on the central sequence algebra. Additionally, in a joint appendix with Joan Bosa, we show that the Villadsen...... algebra of the second type with innite stable rank fails the corona factorization property. In [B], we consider the class of separable C*-algebras which do not admit characters on their central sequence algebra, and show that it has nice permanence properties. We also introduce a new divisibility property...

  10. A third monoclinic polymorph of 3,4,5-trihydroxybenzoic acid monohydrate

    Directory of Open Access Journals (Sweden)

    Güneş Demirtaş

    2011-06-01

    Full Text Available The title compound, C7H6O5·H2O, is a new polymorph of the structures reported by Jiang et al. (2000 [Acta Cryst. C56, 594–595] and Okabe et al. (2001 [Acta Cryst. E57, o764–o766]. The gallic acid molecule is essentially planar (r.m.s. deviation = 0.550 Å. An intramolecular O—H...O hydrogen bond occurs in the gallic acid molecule, which is linked to the water molecule by a further O—H...O hydrogen bond. In the crystal, the components are linked by O—H...O hydrogen bonds. The hydrogen-bonding pattern differs from those reported for the previous polymorphs.

  11. A riddled basin escaping crisis and the universality in an integrate-and-fire circuit

    Science.gov (United States)

    Dai, Jun; He, Da-Ren; Xu, Xiu-Lian; Hu, Chin-Kun

    2018-06-01

    We investigate an integrate-and-fire model of an electronic relaxation oscillator, which can be described by the discontinuous and non-invertible composition of two mapping functions f1 and f2, with f1 being dissipative. Depending on a control parameter d, f2 can be conservative (for d =dc = 1) or dissipative (for d >dc). We find a kind of crisis, which is induced by the escape from a riddled-like attraction basin sea in the phase space. The averaged crisis transient lifetime (〈 τ 〉), the relative measure of the fat fractal forbidden network (η), and the measure of the escaping hole (Δ) show clear scaling behaviors: 〈 τ 〉 ∝(d -dc) - γ, η ∝(d -dc) σ, and Δ ∝(d -dc) α. Extending an argument by Jiang et al. (2004), we derive γ = σ + α, which agrees well with numerical simulation data.

  12. A new car-following model considering velocity anticipation

    International Nuclear Information System (INIS)

    Jun-Fang, Tian; Bin, Jia; Xin-Gang, Li; Zi-You, Gao

    2010-01-01

    The full velocity difference model proposed by Jiang et al. [2001 Phys. Rev. E 64 017101] has been improved by introducing velocity anticipation. Velocity anticipation means the follower estimates the future velocity of the leader. The stability condition of the new model is obtained by using the linear stability theory. Theoretical results show that the stability region increases when we increase the anticipation time interval. The mKdV equation is derived to describe the kink–antikink soliton wave and obtain the coexisting stability line. The delay time of car motion and kinematic wave speed at jam density are obtained in this model. Numerical simulations exhibit that when we increase the anticipation time interval enough, the new model could avoid accidents under urgent braking cases. Also, the traffic jam could be suppressed by considering the anticipation velocity. All results demonstrate that this model is an improvement on the full velocity difference model. (general)

  13. An efficient approach to the analysis of rail surface irregularities accounting for dynamic train-track interaction and inelastic deformations

    Science.gov (United States)

    Andersson, Robin; Torstensson, Peter T.; Kabo, Elena; Larsson, Fredrik

    2015-11-01

    A two-dimensional computational model for assessment of rolling contact fatigue induced by discrete rail surface irregularities, especially in the context of so-called squats, is presented. Dynamic excitation in a wide frequency range is considered in computationally efficient time-domain simulations of high-frequency dynamic vehicle-track interaction accounting for transient non-Hertzian wheel-rail contact. Results from dynamic simulations are mapped onto a finite element model to resolve the cyclic, elastoplastic stress response in the rail. Ratcheting under multiple wheel passages is quantified. In addition, low cycle fatigue impact is quantified using the Jiang-Sehitoglu fatigue parameter. The functionality of the model is demonstrated by numerical examples.

  14. Two (or three) is one too many: testing the flexibility of contextual cueing with multiple target locations.

    Science.gov (United States)

    Zellin, Martina; Conci, Markus; von Mühlenen, Adrian; Müller, Hermann J

    2011-10-01

    Visual search for a target object is facilitated when the object is repeatedly presented within an invariant context of surrounding items ("contextual cueing"; Chun & Jiang, Cognitive Psychology, 36, 28-71, 1998). The present study investigated whether such invariant contexts can cue more than one target location. In a series of three experiments, we showed that contextual cueing is significantly reduced when invariant contexts are paired with two rather than one possible target location, whereas no contextual cueing occurs with three distinct target locations. Closer data inspection revealed that one "dominant" target always exhibited substantially more contextual cueing than did the other, "minor" target(s), which caused negative contextual-cueing effects. However, minor targets could benefit from the invariant context when they were spatially close to the dominant target. In sum, our experiments suggest that contextual cueing can guide visual attention to a spatially limited region of the display, only enhancing the detection of targets presented inside that region.

  15. TEACHER’S POLITENESS IN EFL CLASS

    Directory of Open Access Journals (Sweden)

    Ayfer Sülü

    2015-10-01

    Full Text Available Politeness is considered to promote effective interaction between people. In the context of language teaching, it is believed to enhance learning by providing a lively and friendly atmosphere in classroom (Jiang, 2010. This study investigates an EFL classroom in terms of interaction between English learners and a native English speaking teacher. The aim of the study is to see whether the effects of politeness strategies differ when students and teacher do not share the same culture and native language. Two hours of classes were observed and taperecorded by the researcher. The recordings were transcribed and analyzed by making use of related politeness strategies and functions of speech. Also, three randomly chosen students were interviewed after the class. The findings showed that politeness existed in that EFL classroom and it helped students to have positive feelings towards the lesson and motivated them to participate more in classes.

  16. Static softening following multistage hot deformation of 7150 aluminum alloy: Experiment and modeling

    International Nuclear Information System (INIS)

    Jiang, Fulin; Zurob, Hatem S.; Purdy, Gary R.; Zhang, Hui

    2015-01-01

    Previous studies have demonstrated that the static softening kinetics of 7150 aluminum alloy showed typical sigmoidal behavior at 400 °C and softening plateaus at 300 °C (F.L. Jiang, et al., Mater. Sci. Eng. A, vol. 552, 2012, pp. 269–275). In present work, the static softening mechanisms, the microstructural evolution during post-deformation holding was studied by optical microscopy, scanning electron microscope, electron back-scattered diffraction and transmission electron microscopy. It was demonstrated that recrystallization is essentially absent during post-deformation holding, and that static recovery was the main contribution to static softening. Strain induced precipitation and coarsening caused softening plateaus at 300 °C. In order to better understand the static softening mechanism, physically-based modeling, which integrated recovery and multicomponent particle coarsening modeling, was employed to rationalize the experimental results.

  17. Comparison of improved finite-difference WENO schemes for the implicit large eddy simulation of turbulent non-reacting and reacting high-speed shear flows

    International Nuclear Information System (INIS)

    Zhao, S.; Lardjane, N.; Fedioun, I.

    2014-01-01

    Improved WENO schemes, Z, M, and their combination MZ, originally designed to capture sharper discontinuities than the classical fifth order Jiang-Shu scheme does, are evaluated for the purpose of implicit large eddy simulation of free shear flows. 1D Fourier analysis of errors reveals the built-in filter and dissipative properties of the schemes, which are subsequently applied to the canonical Rayleigh-Taylor and Taylor-Green flows. Large eddy simulations of a transonic non-reacting and a supersonic reacting air/H2 jets are then performed at resolution 128 * 128 * 512, showing no significant difference in the flow statistics. However, the computational time varies from one scheme to the other, the Z scheme providing the smaller wall-time due to larger allowed time steps. (authors)

  18. Benchmarking Insulin Treatment Persistence Among Patients with Type 2 Diabetes Across Different U.S. Payer Segments.

    Science.gov (United States)

    Wei, Wenhui; Jiang, Jenny; Lou, Youbei; Ganguli, Sohini; Matusik, Mark S

    2017-03-01

    treatment persistence across different payers in the United States. Findings indicate that basal insulin persistence patterns are significantly different across different payers, basal insulin types, and devices. This information may be useful in developing targeted approaches to improve T2D patients' persistence with insulin treatment for better glycemic control. This study was funded by Sanofi U.S. through a grant provided to Walgreens for research services. Matusik, Jiang, and Lou are employed by Walgreen Co. Wei and Ganguli were employed by Sanofi U.S. at the time of this study. Study concept and design were contributed by Wei, Ganguli, and Matusik, with assistance from Lou. Jiang took the lead in data collection, along with Lou, and data interpretation was performed by Wei, Lou, and Jiang, along with Ganguli and Matusik. The manuscript was written by Wei and Jiang, along with Ganguli and Matusik, and revised by Wei and Ganguli, along with the other authors.

  19. Existence of positive periodic solution of mutualism system with several delays

    International Nuclear Information System (INIS)

    Wu Haihui; Xia Yonghui; Lin Muren

    2008-01-01

    In this paper, by using Mawhin coincidence degree, some sufficient conditions are obtained for the global existence of positive periodic solutions of a mutualism systems with bounded and unbounded delays. Our results generalize significantly improve those of Gopalsamy and He [Gopalsamy K, He XZ. Persistence, attractivity, and delay in facultative mutualism. J Math Anal Appl 1997;215:154-73], Yang et al. [Yang F, Jiang D, Ying A. Existence of positive solution of multidelays facultative mutualism system. J Eng Math 2002;3:64-8], Chen et al. [Chen FD, Shi JL, Chen XX. Periodicity in Lotka-Volterra facultative mutualism system with several delays. J Eng Math 2004;21(3)] and Xia and Lin [Xia YH, Lin M, Existence of positive periodic solution of mutualism system with infinite delays. Ann Diff Eqs 2005;21(3):448-53

  20. Ross Terrill, The New Chinese Empire — and what it means for the United States

    OpenAIRE

    Eyraud, Henri

    2007-01-01

    Ross Terrill part du constat que la Chine est restée, jusqu'à maintenant, un empire sans contre-pouvoirs et répressif. Mao Zedong, Deng Xiaoping, Jiang Zemin et aujourd'hui Hu Jintao, chacun à leur manière et à leur époque, ont adapté, voire modernisé, les formes de pouvoir de l'empire millénaire. Pour l'auteur, la République populaire de Chine (RPC) a conservé une conception impériale d'elle-même et a réinventé l'autocratie millénaire. Ross Terrill est un observateur politique, mais aussi u...

  1. Research on image reconstruction of DR/SSCT security inspection system

    International Nuclear Information System (INIS)

    Li Jian; Cong Peng

    2008-01-01

    On the basis of DR (Digital Radiography)/CT security inspection system, DR/SSCT (single slice spiral CT) security inspection system was developed. This spiral CT system can improve the CT system's drawbacks. The research work includes in replacing the former data acquisition system by a new system which can acquire projection data of multi-slices and devising the SSCT reconstruction algorithms. Simulation experiments and practical experiments were devised to contrast several algorithms. Interpolation technique was operated in detectors data in order to improve the algorithms. In conclusion, the system exploits an algorithm of weighted average of 360 degree LI (Linear Interpolation) and JH-HI (Jiang Hsieh-Half scan Interpolation). (authors)

  2. Using PISA as an International Benchmark in Standard Setting.

    Science.gov (United States)

    Phillips, Gary W; Jiang, Tao

    2015-01-01

    This study describes how the Programme for International Student Assessment (PISA) can be used to internationally benchmark state performance standards. The process is accomplished in three steps. First, PISA items are embedded in the administration of the state assessment and calibrated on the state scale. Second, the international item calibrations are then used to link the state scale to the PISA scale through common item linking. Third, the statistical linking results are used as part of the state standard setting process to help standard setting panelists determine how high their state standards need to be in order to be internationally competitive. This process was carried out in Delaware, Hawaii, and Oregon, in three subjects-science, mathematics and reading with initial results reported by Phillips and Jiang (2011). An in depth discussion of methods and results are reported in this article for one subject (mathematics) and one state (Hawaii).

  3. The beam diagnostic instruments in Beijing radioactive ion-beam facilities isotope separator on-line

    International Nuclear Information System (INIS)

    Ma, Y.; Cui, B.; Ma, R.; Tang, B.; Chen, L.; Huang, Q.; Jiang, W.

    2014-01-01

    The beam diagnostic instruments for Beijing Radioactive Ion-beam Facilities Isotope Separator On-Line are introduced [B. Q. Cui, Z. H. Peng, Y. J. Ma, R. G. Ma, B. Tang, T. Zhang, and W. S. Jiang, Nucl. Instrum. Methods 266, 4113 (2008); T. J. Zhang, X. L. Guan, and B. Q. Cui, in Proceedings of APAC 2004, Gyeongju, Korea, 2004, http://www.jacow.org , p. 267]. For low intensity ion beam [30–300 keV/1 pA–10 μA], the beam profile monitor, the emittance measurement unit, and the analyzing slit will be installed. For the primary proton beam [100 MeV/200 μA], the beam profile scanner will be installed. For identification of the nuclide, a beam identification unit will be installed. The details of prototype of the beam diagnostic units and some experiment results will be described in this article

  4. Lanthanide metal-organic frameworks

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Peng (ed.) [Nankai Univ., Tianjin (China). Dept. of Chemistry

    2015-03-01

    This book contains the following nine chapters: lanthanide metal-organic frameworks: syntheses, properties, and potential applications (Stephen Fordham, Xuan Wang, Mathieu Bosch, Hong-Cai Zhou); 2. chiral lanthanide metal-organic frameworks (Weisheng Liu, Xiaoliang Tang); 3. Porous lanthanide metal-organic frameworks for gas storage and separation (Bin Li, Banglin Chen); 4. Luminescent lanthanide metal-organic frameworks (Xue-Zhi Song, Shu-Yan Song, Hong-Jie Zhang); 5. Metal-organic frameworks based on lanthanide clusters (Lian Chen, Feilong Jiang, Kang Zhou, Mingyan Wu, Maochun Hong); 6. metal-organic frameworks with d-f cyanide bridges: structural diversity, bonding regime, and magnetism (Marilena Ferbinteanu, Fanica Cimpoesu, Stefania Tanase); 7. transition-lanthanide heterometal-organic frameworks: synthesis, structures, and properties (Wei Shi, Ke Liu, Peng Cheng); 8: MOFs of uranium and the actinides (Juan Su, Jiesheng Chen); 9. Nanostructured and/or nanoscale lanthanide metal-organic frameworks (Zhonghao Zhang, Zhiping Zheng).

  5. Introducing Upfront Money Can Decrease Discounting in Intertemporal Choices with Losses.

    Science.gov (United States)

    Jiang, Cheng-Ming; Sun, Hong-Yue; Zheng, Sheng-Hua; Wang, Liang-Jun; Qin, Yu

    2016-01-01

    People generally tend to advance gains and postpone losses in intertemporal choice. Jiang et al. (2014) recently showed that adding upfront losses or gains to both smaller and sooner (SS) and larger and later (LL) rewards can decrease people's discounting. To account for this decrease, they proposed the salience hypothesis, which states that introducing upfront losses or gains makes the money dimension more salient than not, thus increasing people's preference for LL rewards. Considering that decreasing the discounting of delayed losses is imperative and that most previous studies have focused on intertemporal choices with gains, in the current paper we conducted two experiments and used hypothetical money outcomes to examine whether the effect of upfront money could be extended to intertemporal choices with losses. The results showed that when both SS and LL intertemporal losses were combined with an upfront loss or gain, people's discounting rate decreased and the preference for the SS option increased. This finding further supports the salience account.

  6. RELATIONS BETWEEN RUSSIA AND CHINA AS PART OF THE ASIAN VECTOR OF RUSSIAN DIPLOMACY (1990–2015

    Directory of Open Access Journals (Sweden)

    Alexei D. Voskresenski

    2015-01-01

    Full Text Available The article addresses to the Asian vector of the Russian foreign policy in particularly relations between Russia and China since post-Soviet period until nowdays. The author examines the stages of changing the Russian foreign policy as well as the positions of lobby parties in foreign policy. The article gives the detailed analysis of the cooperation between Russia and China in the Shanghai Cooperation Organization and BRICS. The author examines Russian-Chinese relations in key areas of collaboration such as mutual trade, nuclear power and military-technical sphere. According to the author significant step in Russian-Chinese relations is the Treaty of Good-Neighborliness and Friendly Cooperation signed in the July of 2001 during the visit of Jiang Zemin. The author assesses results of three stages of the relations between Russia and China and future development trends.

  7. An improved Armstrong-Frederick-Type Plasticity Model for Stable Cyclic Stress-Strain Responses Considering Nonproportional Hardening

    Science.gov (United States)

    Li, Jing; Zhang, Zhong-ping; Li, Chun-wang

    2018-03-01

    This paper modified an Armstrong-Frederick-type plasticity model for investigating the stable cyclic deformation behavior of metallic materials with different sensitivity to nonproportional loadings. In the modified model, the nonproportionality factor and nonproportional cyclic hardening coefficient coupled with the Jiang-Sehitoglu incremental plasticity model were used to estimate the stable stress-strain responses of the two materials (1045HR steel and 304 stainless steel) under various tension-torsion strain paths. A new equation was proposed to calculate the nonproportionality factor on the basis of the minimum normal strain range. Procedures to determine the minimum normal strain range were presented for general multiaxial loadings. Then, the modified model requires only the cyclic strain hardening exponent and cyclic strength coefficient to determine the material constants. It is convenient for predicting the stable stress-strain responses of materials in engineering application. Comparisons showed that the modified model can reflect the effect of nonproportional cyclic hardening well.

  8. The brain and heart: dancing in unison?

    Science.gov (United States)

    Erasmus, Rajiv T

    2009-02-01

    Coronary artery disease (CAD) and its main complication myocardial infarction are the leading causes of death globally. Environmental factors don't explain the large amount of variance seen in the development of the disease. Given the strong heritability of CAD, some of the unexplained variance may be due to genetic factors. In this issue of the Journal, Jiang and colleagues report a strong association between brain derived neurotrophic factor (BDNF) Val66Met polymorphism and CAD. There is increasing evidence that BDNF is not only involved in neuronal development but also energy expenditure. The results of this study are likely to give further impetus to researching the complex mechanisms and crosstalk that contribute to the pathogenesis of various polygenic disorders.

  9. Stressed podocytes

    DEFF Research Database (Denmark)

    Svenningsen, Per

    2015-01-01

    and in response to injury induced by endoplasmatic reticulum (ER) stress (Golubinskaya et al., 2015). Their report shed light on the complex regulation of Best3 in podocytes and will help pave the way for future studies on the pathogenesis of kidneys diseases with podocyte injury. This article is protected...... structure appears to be a common finding in acquired proteinuric conditions (Pavenstadt et al., 2003). Identification of genes that are involved in physiological and pathophysiological functions of the podocytes is a major task. Recent studies indicate that Bestrophin (Best) 3 has cell protective functions...... in a number of cell types (Lee et al., 2012, Jiang et al., 2013, Song et al., 2014). In the present issue of Acta Physiologica, Golubinskaya et al. use cultured podocytes, kidneys and isolated glomeruli of the mouse kidney to provide a thorough characterisation of Best3 expression under normal conditions...

  10. Design, synthesis, and antifungal activities of novel triazole derivatives containing the benzyl group

    Directory of Open Access Journals (Sweden)

    Xu K

    2015-03-01

    Full Text Available Kehan Xu,1,* Lei Huang,1,* Zheng Xu,2 Yanwei Wang,1,3 Guojing Bai,1 Qiuye Wu,1 Xiaoyan Wang,1 Shichong Yu,1 Yuanying Jiang1 1School of Pharmacy, Second Military Medical University, Shanghai, 2Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, 3Number 422 Hospital of PLA, Zhanjiang, People’s Republic of China *These authors contributed equally to this work Abstract: In previous studies undertaken by our group, a series of 1-(1H-1,2,4-triazole-1-yl-2-(2,4-difluorophenyl-3-substituted-2-propanols (1a–r, which were analogs of fluconazole, was designed and synthesized by click chemistry. In the study reported here, the in vitro antifungal activities of all the target compounds were evaluated against eight human pathogenic fungi. Compounds 1a, 1q, and 1r showed the more antifungal activity than the others. Keywords: triazole, synthesis, antifungal activity, CYP51

  11. Caras, características y dinámicas del poder en la China actual

    Directory of Open Access Journals (Sweden)

    Raúl Ramírez Ruiz

    2013-02-01

    Full Text Available El presente artículo realiza un análisis de la construcción del “poder” en la China actual. Desde los tiempos de Mao Zedong hasta la elección de Xi Jinping se ha recorrido un camino que permite que hoy en la República Popular se hable de la existencia de un “mando colegiado” sobre el país y de “cinco generaciones de dirigentes”.  A esta situación se ha llegado a través de una intrincada evolución histórica que tiene su clave en las relaciones personales de la cúpula dirigente; su evento histórico más característico en la Revolución Cultural y su objetivo más anhelado en la creación de un “estado de Leyes”. Palabraz Clave: China – Generación de Dirigentes del PCCh – Política en la RPCh – Mao Zedong – Deng Xiaoping – Jiang Zemin – Hu Jintao – Xi Jinping -  Gobernabilidad en China _____________________This article analyzes the construction of the "leadership" in the PRC. From Mao Zedong until Xi Jinping, the goverment in China has come a way that allows today's talk of the existence of a "colective leadership" over the country and "five generation central leadership of CPC." This situation has come through an intricate historical development that has its key in the personal relationships between the leaders of the Party, has its most characteristic historical event in the Cultural Revolution and has its most cherished goal in the creation of a "State of Law".Keywords: China - Generation Leaders of CPC - Politics in the PRC - Mao Zedong - Deng Xiaoping - Jiang Zemin - Hu Jintao - Xi Jinping  - China's Governability

  12. Edouard's (2014) Intensification: An Investigation of Precipitation and Thermodynamic Symmetrization Using a Cloud-Resolving Ensemble

    Science.gov (United States)

    Alvey, G., III; Zipser, E. J.

    2017-12-01

    Literature over the past 10 years has provided conflicting views about the relative importance of precipitation symmetry and convective intensity for tropical cyclone intensification. While several modeling studies (Braun et al. 2006, Guimond et al. 2010, Molinari et al. 2013, Rogers et al. 2013, 2015) have favored intense deep convection, satellite-based composite studies, on the other hand, have offered a differing pathway towards tropical cyclone intensification emphasizing shallow to moderate precipitation (Zagrodnik and Jiang 2014, Tao and Jiang 2015, Alvey et al. 2015). This has left fundamental questions unanswered regarding the relationships between precipitation and TC intensity change: What are the dominant precipitation types, their spatial distributions, and the timing of these features with respect to intensification? And what causes precipitation to symmetrize and increase in the upshear quadrants? One potentially important process, the humidification of upshear quadrants, has been identified to occur nearly coincidental with increased precipitation symmetry prior to and during Edouard's (2014) intensification (Zawislak et al. 2016). While observations from the Global Hawk and P-3 provided important snapshots throughout the life cycle of Edouard (2014), numerical simulations complement and reveal, in more detail, the processes behind these relationships through filling an 48-hour airborne observational gap during a crucial period of intensification between 12-14 Sept. We use a high resolution, full physics ensemble of Edouard (2014) simulated by the Weather Research and Forecasting (WRF) model - Advanced Research WRF (ARW; Skamarock et al., 2008). We deem the quantification of azimuthal variations — with a focus on the shear-relative quadrants — as particularly important, especially early in intensification when thermodynamic and precipitation distributions tend to be more asymmetric. Using a water vapor budget and trajectories we examine whether

  13. Study of provenance properties on ancient porcelain of Yue Kiln at Si-long-kou with NAA

    International Nuclear Information System (INIS)

    Feng Songlin; Fan Dongyu; Feng Xiangqian; Cheng Lin; Lei Yong; Xu Qing; Quan Huishan; Shen Yueming; Zhou Zhexi; Zhang Wenjiang

    2005-01-01

    Chinese ancient porcelain history has lasted about three thousands years from Shang Dynasty (1100∼1600 BC). A large amount of ancient porcelain sherds with accuracy provenance and ages were excavated from a lot of kiln sites in China. Archaeologists and ceramic experts have recognized and researched it with excavated stratum, utensil shape, body quality, glaze color and painting pattern. However, the appearance characteristic of some ancient porcelain manufactured in different kilns is similar. Therefore, it is still difficult to identify the provenance and ages of the samples excavated from some sites using traditional methods. Up, to now, many problems of Chinese ancient porcelain are confused for archaeologist and collecting experts. The elemental composition of ancient porcelain shows certain information of provenance and age. Especially, the sorts and contents of the elements in porcelain didn't change, so it is very useful to determine the provenance of ancient porcelain with elemental composition characteristics. Provenance characteristic is the important scientific information to identify ancient porcelain wares excavated from sites and graves. The porcelain samples of Si-Long-Kou Yue kiln in Zhejiang Province of china have been analyzed with NAA in this paper. The provenance characteristic was compared with it of Hong-Zhou kiln of Jiang-Xi Province and Yao-Zhou kiln of Shan-Xi Province. The experimental data were studied with statistic methods. The results show that the chemical compositions of porcelain body samples for three kilns were different. The difference was been able identified. The porcelain body materials of both Si-Long-Kou Yue kiln and Hong-Zhou kiln of Jiang-Xi were similar. The samples of Yao-Zhou kiln in north of China existed obvious difference.

  14. Semantic similarity between ontologies at different scales

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Qingpeng; Haglin, David J.

    2016-04-01

    In the past decade, existing and new knowledge and datasets has been encoded in different ontologies for semantic web and biomedical research. The size of ontologies is often very large in terms of number of concepts and relationships, which makes the analysis of ontologies and the represented knowledge graph computational and time consuming. As the ontologies of various semantic web and biomedical applications usually show explicit hierarchical structures, it is interesting to explore the trade-offs between ontological scales and preservation/precision of results when we analyze ontologies. This paper presents the first effort of examining the capability of this idea via studying the relationship between scaling biomedical ontologies at different levels and the semantic similarity values. We evaluate the semantic similarity between three Gene Ontology slims (Plant, Yeast, and Candida, among which the latter two belong to the same kingdom—Fungi) using four popular measures commonly applied to biomedical ontologies (Resnik, Lin, Jiang-Conrath, and SimRel). The results of this study demonstrate that with proper selection of scaling levels and similarity measures, we can significantly reduce the size of ontologies without losing substantial detail. In particular, the performance of Jiang-Conrath and Lin are more reliable and stable than that of the other two in this experiment, as proven by (a) consistently showing that Yeast and Candida are more similar (as compared to Plant) at different scales, and (b) small deviations of the similarity values after excluding a majority of nodes from several lower scales. This study provides a deeper understanding of the application of semantic similarity to biomedical ontologies, and shed light on how to choose appropriate semantic similarity measures for biomedical engineering.

  15. Central Vietnam climate over the past five centuries from cypress tree rings

    Science.gov (United States)

    Buckley, Brendan M.; Stahle, Daniel K.; Luu, Hong Truong; Wang, S.-Y. Simon; Nguyen, Tran Quoc Trung; Thomas, Philip; Le, Canh Nam; Ton, That Minh; Bui, The Hoang; Nguyen, Van Thiet

    2017-06-01

    We present the first crossdated tree ring record from central Vietnam, derived from the growth rings of the rare cypress Fokienia hodginsii from the mountains of Quang Nam Province near the Laos border. The Quang Nam Fokienia hodginsii time series (QNFH), based on the crossdated sequences of 71 increment core samples from 37 mature trees, is the third published dendrochronological record from this species. The record extends 667 years from AD 1347 to 2013 and exhibits a mean series intercorrelation of 0.526, similarly significant with the first two published Fokienia hodginsii records: 0.474 for Mu Cang Chai (MCFH) and 0.578 for Bidoup-Nui Ba National Park (BDFH) in the north and south of Vietnam, respectively. The Expressed Population Signal (EPS) for the QNFH record exceeds the generally accepted threshold of 0.85 back to AD 1567, but remains above 0.8 back to 1550. Similar to the MCFH and BDFH records, QNFH expresses statistically significant linkages to regional hydroclimate metrics and the El Niño-Southern Oscillation. Here we present a reconstruction of the Standardized Precipitation Evapotranspiration Index for the month of April, averaged over a large region of Southeast Asia. As with prior studies we demonstrate that cool phase (La Niña) and warm phase (El Niño) events are linked to regional wet and dry conditions, respectively, with linkages to modulation of the surface water temperature over the adjacent sea to the east of Vietnam as well as the Indian Ocean. A late eighteenth century megadrought that is expressed widely across South and Southeast Asia, and notably from the MCFH and BDFH records described above, is not as pronounced in Central Vietnam and we explore the reasons why.

  16. Laboratory training manual on the use of isotopes and radiation in soil-plant relations research

    International Nuclear Information System (INIS)

    1964-01-01

    The International Atomic Energy Agency (IAEA) and the Food and Agriculture Organization of the United Nations (FAO) in co-operation with local authorities in various countries have jointly sponsored international laboratory training courses on the use of isotopes and radiation in specialized fields of agriculture. Outstanding scientists from various countries have given lectures and devised and conducted the laboratory exercises; research workers from all over the world have attended these courses. In addition, under the United Nations Expanded Programme of Technical Assistance the IAEA in co-operation with host governments has conducted similar regional courses. This laboratory manual is a natural outgrowth of these activities. The contents represents the efforts not only of the IAEA and FAO Secretariats but also of the various instructors who have participated in the courses, a Special Consultant, Victor Middelboe, and a panel of scientists who met in Vienna from 3 to 7 September 1962 and revised the initial version assembled by Hans Broeshart and Chai Moo Cho of the IAEA Secretariat. The present manual consists of two parts: a basic part which contains general information and laboratory exercises on the properties of radiation and the principles of use of radioactive tracers, and a second part which contains a series of detailed laboratory exercises in the field of soil-plant relationships. It is intended to publish at least four additional parts on the subjects of the use of isotopes and radiation in animal science, agricultural biochemistry, entomology and plant pathology. This manual, dealing with an important aspect of the peaceful application and use of atomic energy, should prove helpful not only to those working with the IAEA and FAO training programmes but to other research scientists dealing with the development and use of new information in agricultural science all over the world

  17. Cigarette smoking among Thai Buddhist monks, central and eastern Thailand.

    Science.gov (United States)

    Chaveepojnkamjorn, Wisit; Pichainarong, Natchaporn

    2005-03-01

    A cross-sectional study was conducted from June to December, 2003 among Thai Buddhist monks in 4 provinces of the central region (Nonthaburi, Pathum Thani, Saraburi and Chai Nat) and in 4 provinces of the eastern region (Chachoengsao, Rayong, Trat, and Sa Kaeo) of Thailand. Data were collected using face to face interviews, questionnaires, and physical examination reports (weight, height, heart rate, blood pressure, etc) as the research tools. This study focused on sociodemographics, history of illness, and smoking behavior. The proportion of the cigarette smoking was 47.6% of the total of 920 Buddhist monks. The age group 20-34 years, Maha Nikaya section and Public temple were the majority of the study subjects. Multivariate analysis revealed that only four factors were related to smoking consumption: dharma education, Naktharm To (grade 2) (OR = 0.6, 95% Cl: 0.4-0.9), Naktharm Aek (grade 3) or above (OR = 0.4, 95% Cl: 0.2-0.6); Lay education, secondary school (OR = 0.7, 95% Cl: 0.5-0.9), bachelor degree or above (OR = 0.4, 95% Cl: 0.2-0.8); systolic blood pressure > or = 140 mmHg (OR = 1.8, 95% Cl: 1.1-2.8) and history of respiratory illness (OR = 3.2, 95% Cl: 1.5-6.9). As a result, dharma education and well educated persons were the crucial factors which led to success in decreasing cigarette smoking. Smoking cessation campaigns and education of the consequences of smoking are strongly recommended among risk groups.

  18. Associations between prescribed Chinese herbal medicine and risk of hepatocellular carcinoma in patients with chronic hepatitis B: a nationwide population-based cohort study.

    Science.gov (United States)

    Tsai, Tzung-Yi; Livneh, Hanoch; Hung, Tsung-Hsing; Lin, I-Hsin; Lu, Ming-Chi; Yeh, Chia-Chou

    2017-01-25

    Patients with chronic hepatitis B (CHB) are reported to exhibit higher risk of subsequent hepatocellular carcinoma (HCC). However, it remains unclear if Chinese herbal medicine (CHM), an important category of traditional Chinese medicine (TCM), may lower HCC risk in this population. So this study aimed to investigate the effects of CHM on HCC risk among patients with CHB. This cohort study used the Taiwanese National Health Insurance Research Database to identify 21 020 newly diagnosed patients with CHB from 1998 to 2007. Among them, 8640 received CHM products after CHB onset (CHM users), and the remaining 12 380 patients were designated as a control group (non-CHM users). All enrolees were followed until the end of 2012 to measure the incidence rate and HR of HCC. During 15 years of follow-up, 371 CHM users and 958 non-CHM users developed HCC, representing an incidence rate of 5.28% and 10.18% per 1000 person-years, respectively. CHM users had significantly lower HCC risk compared with non-CHM users (adjusted HR=0.63, 95% CI 0.56 to 0.72). The predominant effect was observed in those receiving CHM products for more than 180 days (adjusted HR=0.52). Some CHM products, such as Hedyotis diffusa, Scutellaria barbata, Rehmannia glutinosa, Isatis tinctoria, Yi Guan Jian, Xiao Chai Hu Tang, Wu Ling San and Gan Lu Yin, were significantly associated with lower risk of HCC. The use of CHM was associated with a significantly reduced HCC risk in patients with CHB, which supports the integration of TCM with CHM into clinical practice to influence a favourable prognosis. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  19. The assessment of land use change impact on watersheds runoff using SWAT: case study of Urmia Lake in Iran

    Science.gov (United States)

    Jabbari, Anahita; Jarihani, Ben; Rezaie, Hossein

    2015-04-01

    Lake Urmia, long counted among the world's largest saltwater lakes, contains only 5% of the amount of water it did just 20 years ago. The decline is generally blamed on a combination of drought, increased water diversion for irrigated agriculture within the lake's watershed and land use mismanagement. It has been believed that land use changes in Lake Urmia basin is one of the most important factors in shrinkage of Urmia Lake in recent decades. Transforming the traditional agricultural practices (i.e., wheat) to the more water consuming practices (i.e., apple orchards) is one of the most important reasons increased agricultural water consumption in the watershed. In this study we assessed the effect of the land use changes of watershed in hydrological runoff processing in the Nazloo chai watershed, one of the most important river basins of the Urmia Lake basin. Actually the rapid and at the same time unreasonable transformations of land use in farm lands of Urmia lake sub basins, extremely has been raised the amount of blue water (surface or groundwater) consumption in watershed which leads to dramatic decrement of watershed runoff amounts. One of the most unfavorable consequences of land use change was changing the blue and green (rainwater insofar as it does not become runoff) water usage patterns in watershed, in addition to water use increment. The soil and water assessment tool (SWAT), one of the most important and reliable models which was used to model the rainfall runoff, has been used in current study. The land use maps were extracted from Landsat images archives for the most severe turning points in respect of land use change in the recent 30 years. After calibrating the model, several land use patterns of historical data were used in the model to produce the runoff. The results showed the strong relation between land use change and runoff reduction in the Lake Urmia basin.

  20. Prescription patterns of Chinese herbal products for patients with sleep disorder and major depressive disorder in Taiwan.

    Science.gov (United States)

    Chen, Yi-Lin; Lee, Chien-Ying; Huang, Kuang-Hua; Kuan, Yu-Hsiang; Chen, Ming

    2015-08-02

    Chinese herbal products (CHPs) are commonly prescribed for sleep disorder and major depressive disorder (MDD). The aim of this study was to investigate the prescription patterns of CHPs and Western medicine for patients with these disorders in Taiwan, and analyze the frequency of using single herbs (SHs) and herbal formulas (HFs). In this retrospective population-based study secondary data analysis was performed using data from Taiwan's Longitudinal Health Insurance Database (LHID) between January 2007 and December 2011. In total, 1000,000 beneficiaries from the LHID were randomly selected from the 2010 registry for beneficiaries of the National Health Insurance Research Database. Patients with sleep disorder and MDD according to the International Classification of Diseases, Ninth Revision, Clinical Modification codes 307.40 and 311, respectively. Among a total of 11,030 patients with sleep disorder, 9619 used Western medicine, 1334 used CHPs, and 77 used both, Among a total of 11,571 patients with MDD, 11,389 used Western medicine, 131 used CHPs, and 51 used both. Regardless of disorder type, women were predominant The majority of the patients were aged 22-44 years, had a monthly income of NT$17,281-NT$22,800, and lived in an area with Level 1 and Level 2 urbanization. Of the patients with sleep disorder, 1411 had used CHPs and visited a clinic 5298 times on average. Of the patients with MDD, 182 had used CHPs and visited a clinic 755 times on average. The three most commonly used SHs and HFs were Ziziphi Spinosae Semen, Polygoni Multiflori Caulis, and Polygalae Radix, and Jia-Wei-Xiao-Yao-San, Suan-Zao-Ren-Tang, and Chai-Hu-Chia-Lung-Ku-Mu-Li-Tang, respectively. Chinese herbal products including SHs and HFs are prescribed for patients with sleep disorder and MDD. However, the efficacy and safety of CHPs for sleep disorder and MDD need to be further evaluated. Copyright © 2015. Published by Elsevier Ireland Ltd.

  1. Prescription frequency and patterns of Chinese herbal medicine for liver cancer patients in Taiwan: a cross-sectional analysis of the National Health Insurance Research Database.

    Science.gov (United States)

    Ting, Chin-Tsung; Kuo, Chian-Jue; Hu, Hsiao-Yun; Lee, Ya-Ling; Tsai, Tung-Hu

    2017-02-20

    Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. Chinese herbal medicine (CHM) is frequently provided to HCC patients. The aim of this study was to understand the prescription frequency and patterns of CHM for HCC patients by analyzing the claims data from the National Health Insurance (NHI) in Taiwan. We identified 73918 newly diagnosed HCC subjects from the database of Registry for Catastrophic Illness during 2002 to 2009 and to analyze the frequency and pattern of corresponding CHM prescriptions for HCC patients. There were a total of 685,079 single Chinese herbal prescriptions and 553,952 Chinese herbal formula prescriptions used for 17,373 HCC subjects before 2 years of HCC diagnosis. Among the 13,093 HCC subjects who used CHMs after HCC diagnosis, there were 462,786 single Chinese herbal prescriptions and 300,153 Chinese herbal formula prescriptions were counted. By adjusting with person-year and ratio of standardized incidence rate, the top ten prescribed single herbal drugs and Chinese herbal formulas for HCC patients were described in our study. Among them, we concluded that, Oldenlandia diffusa (Chinese herbal name: Bai-Hua-She-She-Cao), Radix et Rhizoma Rhei (Da Huang) and the herbal preparation of Xiao-Chai-Hu-Tang and Gan-Lu-Yin, were the most obviously increased and important CHMs been used for HCC patients. We established an accurate and validated method for the actual frequency and patterns of CHM use in treating HCC in Taiwan. We propose that these breakthrough findings may have important implications for HCC therapy, clinical trials and modernization of CHM.

  2. Enhanced anticancer efficacy of paclitaxel through multistage tumor-targeting liposomes modified with RGD and KLA peptides

    Directory of Open Access Journals (Sweden)

    Sun J

    2017-02-01

    Full Text Available Jiawei Sun,1 Lei Jiang,2 Yi Lin,3 Ethan Michael Gerhard,4 Xuehua Jiang,1 Li Li,3 Jian Yang,4 Zhongwei Gu3 1West China School of Pharmacy, Sichuan University, Chengdu, Sichuan, 2Department of Pharmaceutics, China Pharmaceutical University, Nanjing, Jiangsu, 3National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, Sichuan, People’s Republic of China; 4Department of Biomedical Engineering Materials Research Institute, The Huck Institutes of The Life Sciences, The Pennsylvania State University, University Park, PA, USA Abstract: Mitochondria serve as both “energy factories” and “suicide weapon stores” of cells. Targeted delivery of cytotoxic drugs to the mitochondria of tumor cells and tumor vascular cells is a promising strategy to improve the efficacy of chemotherapy. Here, multistage tumor-targeting liposomes containing two targeted peptide-modified lipids, cRGD-PEG2000-DSPE and KLA-PEG2000-DSPE, were developed for encapsulation of the anticancer drug paclitaxel (PTX, RGD-KLA/PTX-Lips. Compared with Taxol (free PTX, RGD/PTX-Lips and KLA/PTX-Lips, the half-maximal inhibitory concentration (IC50 value of RGD-KLA/PTX-Lips in vitro was 1.9-, 36.7- and 22.7-fold lower with 4T1 cells, respectively, because of higher levels of cellular uptake. Similar results were also observed with human umbilical vascular endothelial cells (HUVECs. An apoptosis assay showed that the total apoptotic ratio of RGD-KLA/PTX-Lips was the highest because of the mitochondria-targeted drug delivery and the activation of mitochondrial apoptosis pathways, as evidenced by visible mitochondrial localization, decreased mitochondrial membrane potential, release of cytochrome c and increased activities of caspase-9 and caspase-3. The strongest tumor growth inhibition (TGI; 80.6% and antiangiogenesis effects without systemic toxicity were also observed in RGD-KLA/PTX-Lip-treated 4T1 tumor xenograft BALB/c mice. In conclusion, these multistage

  3. Effect of micro-nano-hybrid structured hydroxyapatite bioceramics on osteogenic and cementogenic differentiation of human periodontal ligament stem cell via Wnt signaling pathway

    Directory of Open Access Journals (Sweden)

    Mao LX

    2015-11-01

    Full Text Available Lixia Mao,1,* Jiaqiang Liu,1,* Jinglei Zhao,1 Jiang Chang,2 Lunguo Xia,1 Lingyong Jiang,1 Xiuhui Wang,2 Kaili Lin,2,3 Bing Fang11Center of Craniofacial Orthodontics, Department of Oral and Cranio-maxillofacial Science, Top Priority Clinical Medical Center of Shanghai Municipal Commission of Health and Family Planning, Ninth People’s Hospital Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai Jiao Tong University, 2State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 3Shanghai Engineering Research Center of Tooth Restoration and Regeneration, School of Stomatology, Tongji University, Shanghai, People’s Republic of China*These authors contributed equally to this workAbstract: The surface structure of bioceramic scaffolds is crucial for its bioactivity and osteoinductive ability, and in recent years, human periodontal ligament stem cells have been certified to possess high osteogenic and cementogenic differential ability. In the present study, hydroxyapatite (HA bioceramics with micro-nano-hybrid surface (mnHA [the hybrid of nanorods and microrods] were fabricated via hydrothermal reaction of the α-tricalcium phosphate granules as precursors in aqueous solution, and the effects of mnHA on the attachment, proliferation, osteogenic and cementogenic differentiations of human periodontal ligament stem cells as well as the related mechanisms were systematically investigated. The results showed that mnHA bioceramics could promote cell adhesion, proliferation, alkaline phosphatase (ALP activity, and expression of osteogenic/cementogenic-related markers including runt-related transcription factor 2 (Runx2, ALP, osteocalcin (OCN, cementum attachment protein (CAP, and cementum protein (CEMP as compared to the HA bioceramics with flat and dense surface. Moreover, mnHA bioceramics stimulated gene expression of low-density lipoprotein receptor

  4. Does Eating Chicken Feet With Pickled Peppers Cause Avian Influenza? Observational Case Study on Chinese Social Media During the Avian Influenza A (H7N9) Outbreak.

    Science.gov (United States)

    Chen, Bin; Shao, Jian; Liu, Kui; Cai, Gaofeng; Jiang, Zhenggang; Huang, Yuru; Gu, Hua; Jiang, Jianmin

    2018-03-29

    social media. Our findings suggested the importance of responding to common questions and misconceptions on social media platforms from the beginning of disease outbreaks. Authorities need to release clear and reliable information related to the popular topics early on. The microbloggers posting correct information should be empowered and their posts could be promoted to clarify false information. Equal importance should be attached to clarify misinformation in both the outbreak and nonoutbreak areas. ©Bin Chen, Jian Shao, Kui Liu, Gaofeng Cai, Zhenggang Jiang, Yuru Huang, Hua Gu, Jianmin Jiang. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 29.03.2018.

  5. Constraints on voltage sensor movement in the shaker K+ channel.

    Science.gov (United States)

    Darman, Rachel B; Ivy, Allison A; Ketty, Vina; Blaustein, Robert O

    2006-12-01

    In nerve and muscle cells, the voltage-gated opening and closing of cation-selective ion channels is accompanied by the translocation of 12-14 elementary charges across the membrane's electric field. Although most of these charges are carried by residues in the S4 helix of the gating module of these channels, the precise nature of their physical movement is currently the topic of spirited debate. Broadly speaking, two classes of models have emerged: those that suggest that small-scale motions can account for the extensive charge displacement, and those that invoke a much larger physical movement. In the most recent incarnation of the latter type of model, which is based on structural and functional data from the archaebacterial K(+) channel KvAP, a "voltage-sensor paddle" comprising a helix-turn-helix of S3-S4 translocates approximately 20 A through the bilayer during the gating cycle (Jiang, Y., A. Lee, J. Chen, V. Ruta, M. Cadene, B.T. Chait, and R. MacKinnon. 2003. Nature. 423:33-41; Jiang, Y., V. Ruta, J. Chen, A. Lee, and R. MacKinnon. 2003. Nature. 423:42-48.; Ruta, V., J. Chen, and R. MacKinnon. 2005. Cell. 123:463-475). We used two methods to test for analogous motions in the Shaker K(+) channel, each examining the aqueous exposure of residues near S3. In the first, we employed a pore-blocking maleimide reagent (Blaustein, R.O., P.A. Cole, C. Williams, and C. Miller. 2000. Nat. Struct. Biol. 7:309-311) to probe for state-dependent changes in the chemical reactivity of substituted cysteines; in the second, we tested the state-dependent accessibility of a tethered biotin to external streptavidin (Qiu, X.Q., K.S. Jakes, A. Finkelstein, and S.L. Slatin. 1994. J. Biol. Chem. 269:7483-7488; Slatin, S.L., X.Q. Qiu, K.S. Jakes, and A. Finkelstein. 1994. Nature. 371:158-161). In both types of experiments, residues predicted to lie near the top of S3 did not exhibit any change in aqueous exposure during the gating cycle. This lack of state dependence argues against

  6. A Newly Designed Mobile-Based Computerized Cognitive Addiction Therapy App for the Improvement of Cognition Impairments and Risk Decision Making in Methamphetamine Use Disorder: Randomized Controlled Trial.

    Science.gov (United States)

    Zhu, Youwei; Jiang, Haifeng; Su, Hang; Zhong, Na; Li, Runji; Li, Xiaotong; Chen, Tianzhen; Tan, Haoye; Du, Jiang; Xu, Ding; Yan, Huan; Xu, Dawen; Zhao, Min

    2018-06-20

    Cognitive rehabilitation therapy has been found to improve cognitive deficits and impulse control problems in methamphetamine use disorder (MUD). However, there is limited research regarding this therapy's feasibility when using mobile-based health technologies in supporting recovery from MUD in China. The main aim of this study was to test whether 4 weeks of a newly designed computerized cognitive addiction therapy (CCAT) app can improve cognitive impairments, eliminate drug-related attention bias, and attenuate risk decision-making behaviors in participants with MUD. Forty MUD participants were assigned randomly to either the CCAT group (n=20), who received 4 weeks of CCAT plus regular detoxification treatment as usual, or the control group (n=20), who only received the regular detoxification treatment as usual, in drug rehabilitation centers in Shanghai. The CCAT was designed by combine methamphetamine use-related picture stimuli with cognitive training with the aim of improving cognitive function and eliminating drug-related attention bias. The CogState Battery, Delay Discounting Task (DDT), Iowa Gambling Task (IGT), and Balloon Analog Risk Task (BART) were administered face-to-face to all participants before and after CCAT interventions. Forty male patients were recruited. The mean age was 32.70 (SD 5.27) years in the CCAT group and mean 35.05 (SD 8.02) years in the control group. Compared to the control group, CCAT improved working memory in the CCAT group (P=.01). Group×time interactions were observed among DDT, IGT, and BART tasks, with rates of discounting delayed rewards, IGT, and BART scores (Pcognitive impairment and impulsive control in MUD. Further study is needed to understand the underlying brain mechanisms of the cognitive therapy. ClinicalTrials.gov NCT03318081; https://clinicaltrials.gov/ct2/show/NCT03318081 (Archived by WebCite at https://clinicaltrials.gov/ct2/show/NCT03318081). ©Youwei Zhu, Haifeng Jiang, Hang Su, Na Zhong, Runji Li

  7. Metformin inhibits proliferation and cytotoxicity and induces apoptosis via AMPK pathway in CD19-chimeric antigen receptor-modified T cells

    Directory of Open Access Journals (Sweden)

    Mu Q

    2018-04-01

    Full Text Available Qian Mu,1,2,* Miao Jiang,1,* Yuzhu Zhang,1 Fei Wu,1 Hui Li,1 Wen Zhang,1 Fang Wang,1 Jiang Liu,1 Liang Li,1 Dongshan Wang,3 Wenjuan Wang,1 Shiwu Li,1 Haibo Song,4 Dongqi Tang1 1Gene and Immunotherapy Center, The Second Hospital of Shandong University, Jinan, People’s Republic of China; 2Department of Endocrinology and Metabolism, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 3Health Management Center, The Second Hospital of Shandong University, Jinan, People’s Republic of China; 4Central Research Laboratory, Zibo Maternal and Child Health Hospital, Affiliated to Shandong Academy of Medical Science, Zibo, People’s Republic of China *These authors contributed equally to this work Background: CD19-chimericantigen receptor (CAR modified T cells (CD19-CAR T cells have been well documented to possess potent anti-tumor properties against CD19-expressingleukemia cells. As a traditional medicine, metformin has been widely used to treat type II diabetes mellitus and more recently has become a candidate for the treatment of cancer. However, no report has revealed the direct effect of metformin on CD19-CAR T cell biological function and its underling mechanisms. Purpose: The purpose of this research was to explore the effect of metformin on CD19-CAR T cell biological function and the mechanisms involved. Methods: CD19-CAR T cells proliferation, apoptosis and cytotoxicity were mainly tested by CCK-8 assay, flow cytometry and ELISA. The detection of mechanism primarily used western blot. Bioluminescence imaging is the main application technology of animal studies. Results: In the current study, it was found that metformin inhibited CD19-CAR T cell proliferation and cytotoxicity and induced apoptosis. Furthermore, our study revealed that metformin activated AMPK and suppressed mTOR and HIF1α expression. By using an AMPK inhibitor, compound C, we demonstrated the crucial roles of AMPK in CD19

  8. Recovery of nitrogen and phosphorus from alkaline fermentation liquid of waste activated sludge and application of the fermentation liquid to promote biological municipal wastewater treatment.

    Science.gov (United States)

    Tong, Juan; Chen, Yinguang

    2009-07-01

    In previous publications we reported that by controlling the pH at 10.0 the accumulation of short-chain fatty acids (SCFA) during waste activated sludge (WAS) fermentation was remarkably improved [Yuan, H., Chen, Y., Zhang, H., Jiang, S., Zhou, Q., Gu, G., 2006. Improved bioproduction of short-chain fatty acids (SCFAs) from excess sludge under alkaline conditions. Environ. Sci. Technol. 40, 2025-2029], but significant ammonium nitrogen (NH(4)-N) and soluble ortho-phosphorus (SOP) were released [Chen, Y., Jiang, S., Yuan, H., Zhou, Q., Gu, G., 2007. Hydrolysis and acidification of waste activated sludge at different pHs. Water Res. 41, 683-689]. This paper investigated the simultaneous recovery of NH(4)-N and SOP from WAS alkaline fermentation liquid and the application of the fermentation liquid as an additional carbon source for municipal wastewater biological nitrogen and phosphorus removal. The central composite design (CCD) of the response surface methodology (RSM) was employed to optimize and model the simultaneous NH(4)-N and SOP recovery from WAS alkaline fermentation liquid. Under the optimum conditions, the predicted and experimental recovery efficiency was respectively 73.4 and 75.7% with NH(4)-N, and 82.0 and 83.2% with SOP, which suggested that the developed models described the experiments well. After NH(4)-N and SOP recovery, the alkaline fermentation liquid was added to municipal wastewater, and the influence of volume ratio of fermentation liquid to municipal wastewater (FL/MW) on biological nitrogen and phosphorus removal was investigated. The addition of fermentation liquid didn't significantly affect nitrification. Both SOP and total nitrogen (TN) removal were increased with fermentation liquid, but there was no significant increase at FL/MW greater than 1/35. Compared to the blank test, the removal efficiency of SOP and TN at FL/MW=1/35 was improved from 44.0 to 92.9%, and 63.3 to 83.2%, respectively. The enhancement of phosphorus and nitrogen

  9. Enhancement of radiotherapy efficacy by miR-200c-loaded gelatinase-stimuli PEG-Pep-PCL nanoparticles in gastric cancer cells

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    Cui FB

    2014-05-01

    Full Text Available Fang-bo Cui,1,* Qin Liu,1,* Ru-Tian Li,1 Jie Shen,1 Pu-yuan Wu,1 Li-Xia Yu,1 Wen-jing Hu,1 Feng-lei Wu,2 Chun-Ping Jiang,1 Guo-feng Yue,2 Xiao-Ping Qian,1 Xi-Qun Jiang,3 Bao-Rui Liu11The Comprehensive Cancer Center of Drum-Tower Hospital, Medical School of Nanjing University and Clinical Cancer Institute of Nanjing University, Nanjing, 2Nanjing Medical University, 3Laboratory of Mesoscopic Chemistry and Department of Polymer Science and Engineering, College of Chemistry and Chemical Engineering, Nanjing University, Nanjing, People's Republic of China*These authors contributed equally to this workAbstract: Radiotherapy is the main locoregional control modality for many types of unresectable tumors, including gastric cancer. However, many patients fail radiotherapy due to intrinsic radioresistance of cancer cells, which has been found to be strongly associated with cancer stem cell (CSC-like properties. In this study, we developed a nanoparticle formulation to deliver miR-200c, which is reported to inhibit CSC-like properties, and then evaluated its potential activity as a radiosensitizer. miR-200c nanoparticles significantly augmented radiosensitivity in three gastric cancer cell lines (sensitization enhancement ratio 1.13–1.25, but only slightly in GES-1 cells (1.06. In addition to radioenhancement, miR-200c nanoparticles reduced the expression of CD44, a putative CSC marker, and the percentage of CD44+ BGC823 cells. Meanwhile, other CSC-like properties, including invasiveness and resistance to apoptosis, could be suppressed by miR-200c nanoparticles. CSC-associated radioresistance mechanisms, involving reactive oxygen species levels and DNA repair capacity, were also attenuated. We have demonstrated that miR-200c nanoparticles are an effective radiosensitizer in gastric cancer cells and induce little radiosensitization in normal cells, which suggests that they are as a promising candidate for further preclinical and clinical evaluation

  10. Inhibitory effects of silibinin on proliferation and lung metastasis of human high metastasis cell line of salivary gland adenoid cystic carcinoma via autophagy induction

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    Jiang C

    2016-10-01

    Full Text Available Canhua Jiang,1 Shufang Jin,1 Zhisheng Jiang,1 Jie Wang2 1Department of Oral and Maxillofacial Surgery, Xiangya Hospital, 2Department of Immunology, Xiangya School of Medicine, Central South University, Changsha, Hunan, People’s Republic of China Objective: To investigate the possible mechanisms and effects of silibinin (SIL on the proliferation and lung metastasis of human lung high metastasis cell line of salivary gland adenoid cystic carcinoma (ACC-M.Methods: A methyl thiazolyl tetrazolium assay was performed to detect the inhibitory effects of SIL on the proliferation of ACC-M cells in vitro. Fluorescence microscopy and transmission electron microscopy were used to observe the autophagic process. Western blot was performed to detect the expression of microtube-related protein 1 light-chain 3 (LC3. An experimental adenoid cystic carcinoma (ACC lung metastasis model was established in nude mice to detect the impacts of SIL on lung weight and lung cancer nodules. Immunohistochemistry was used to detect the expressions of LC3 in human ACC samples and normal salivary gland tissue samples.Results: SIL inhibited the proliferation of ACC-M cells in a dose- and time-dependent manner, and inductively increased the autophagic bodies in ACC-M cells. Furthermore, SIL could increase the expression of LC3 in ACC-M cells and promote the conversion of LC3-I into LC3-II in a dose- and time-dependent manner. In the ACC lung metastasis model, the lung weight and left and right lung nodules in the SIL-treated group were significantly less than those in the control group (P<0.05. The expressions of LC3-I and LC3-II as well as the positive expression rate of LC3 (80% significantly increased, but the positive expression of LC3 in human ACC (42.22% reduced significantly.Conclusion: SIL could inhibit the proliferation and lung metastasis of ACC-M cells by possibly inducing tumor cells autophagy. Keywords: silibinin, adenoid cystic carcinoma, ACC-M cells, autophagy

  11. The feature of the focal mechanism solutions and tectonic stress field around the focus of Zaduo earthquake (Ms 6.3) in eastern Tibet

    Science.gov (United States)

    Yang, Y.; Zeng, Z.; Shuang, X.; Li, X.

    2017-12-01

    On 17th October, 2016, an earthquake of Ms6.3 occurred in Zaduo County, Qinghai Province (32.9°N, 95.0°E), 159 km away from the epicenter of Yushu Ms7.3 earthquake in 2011. The earthquake is located in the eastern Tibet Plateau and the north region of Eastern Himalayan Syntaxis. Using the broadband seismic waveform data form regional networks, we determined the focal mechanism solutions (FMSs) of 83 earthquakes (M>3.5) occurred in Zaduo and its adjacent areas from 2009 to 2017. We also collected another 63 published FMSs and then inversed the current tectonic stress field in study region using the damped linear inversion method. The results show that the Zaduo earthquake is a normal oblique earthquake. The FMSs in our study region are mainly in strike-slip and normal fault patterns. The strike-slip earthquakes are mainly distributed in Yushu-Ganzi, Zaduo and Yanshiping fault zones, and the normal faulting events occurred in Nu Jiang fault zone and Nierong County and its vicinity, the south and southwest of the study areas. The tectonic stress field results indicate that the stress distribution in the north and east of the study region changes homogeneously and slowly. From west to east, the σ1 gradually changes from NNE to NE direction, and the σ3 varies from NWW to NW direction. Both the maximum (σ1) and minimum (σ3) principal stress axes in the study area are nearly horizontal, except in the Nu Jiang fault zone and its vicinity, the south of the study area, which is in a normal faulting stress regime (σ1 is vertical and σ3 is horizontal). The localized normal faulting stress field in the south area, which is almost limited in a semicircle, indicates that a high pressure and low viscosity body with low S-wave velocity and high conductivity might exists beneath the anomaly area. And there may be another semicircle abnormal area beyond the south of the study region. Waveform data for this study are provided by Data Management Centre of China National Seismic

  12. Aripiprazole-associated tic in a schizophrenia patient

    Directory of Open Access Journals (Sweden)

    Guo X

    2015-03-01

    Full Text Available Xieli Guo,1,2,* Dali Lu,3,* Yugang Jiang1 1Department of Neurosurgery, Second Xiangya Hospital of Central South University, Changsha, Hunan, People’s Republic of China; 2Department of Neurosurgery, Jinjiang Hospital of Quanzhou Medical College, Jinjiang, Fujian, People’s Republic of China; 3Department of Psychiatry, Xiamen Xianyue Hospital, Xiamen, Fujian, People’s Republic of China *These authors contributed equally to this work Abstract: Tic disorder, characterized by the presence of both motor and vocal tics is common in adolescents and adults. Antipsychotics including typical antipsychotics and atypical antipsychotics are generally recognized by experts as the most effective pharmacological treatment for tics. However, previous studies suggest that tic-like symptoms might manifest during treatment with atypical antipsychotics such as clo­zapine, quetiapine, but not aripiprazole. We present the first case, to our knowledge, of an adult schizophrenia patient who developed tics during treatment with aripiprazole. Keywords: aripiprazole, antipsychotics, tic, schizophrenia, side effect

  13. Andrographolide inhibits hypoxia-inducible factor-1 through phosphatidylinositol 3-kinase/AKT pathway and suppresses breast cancer growth

    Directory of Open Access Journals (Sweden)

    Li J

    2015-02-01

    Full Text Available Jie Li,1 Chao Zhang,1 Hongchuan Jiang,1 Jiao Cheng21Department of General Surgery, 2Department of Gynaecology and Obstetrics, Beijing Chao-Yang Hospital, Beijing, People’s Republic of ChinaAbstract: Hypoxia-inducible factor-1 (HIF-1 is a master regulator of the transcriptional response to hypoxia. HIF-1α is one of the most compelling anticancer targets. Andrographolide (Andro was newly identified to inhibit HIF-1 in T47D cells (a half maximal effective concentration [EC50] of 1.03×10-7 mol/L, by a dual-luciferase reporter assay. It suppressed HIF-1α protein and gene accumulation, which was dependent on the inhibition of upstream phosphatidylinositol 3-kinase (PI3K/AKT pathway. It also abrogated the expression of HIF-1 target vascular endothelial growth factor (VEGF gene and protein. Further, Andro inhibited T47D and MDA-MB-231 cell proliferation and colony formation. In addition, it exhibited significant in vivo efficacy and antitumor potential against the MDA-MB-231 xenograft in nude mice. In conclusion, these results highlighted the potential effects of Andro, which inhibits HIF-1, and hence may be developed as an antitumor agent for breast cancer therapy in future.Keywords: Andrographolide (Andro, HIF-1α, inhibit, breast cancer, hypoxia, PI3k/AKT/mTOR pathway

  14. New Approaches to Cross-Strait Integration and Its Impacts on Taiwan’s Domestic Economy: An Emerging “Chaiwan”?

    Directory of Open Access Journals (Sweden)

    Gordon C. K. Cheung

    2010-04-01

    Full Text Available Taiwan’s Legislative Yuan and Presidential elections in January and March 2008 respectively re-orientated cross-Strait relations from hostility to co-operation. On 4 November 2008, Chen Yunlin, head of the Association for Relations Across the Taiwan Straits (ARATS, and Chiang Pin-kun (Jiang Bingkun, chairman of Taiwan’s Straits Exchange Foundation (SEF, meeting in the Second Chiang-Chen Talks in Taiwan, took a historical step in the further development of cross-Strait relations. Agreements were signed on direct air and sea transport, postal services and food-safety security. On 22 December 2009, the Fourth Chiang- Chen Talks took place in Taizhong and more substantial and technical agreements were signed on agriculture, inspection/ accreditation and fisheries. It seems that continuous integration between China and Taiwan is inevitable. To address the implications of this process for Taiwan’s domestic economy, four dimensions of the current cross-Strait relationship are scrutinized: guanxi, plutocracy, legalism and the idea of a Chinese Common Market. It is argued that in order to intensify economic co-operation across the Taiwan Strait, more institutionalization of the cross-Strait relationship must be brought about.

  15. Patients harboring EGFR mutation after primary resistance to crizotinib and response to EGFR-tyrosine kinase inhibitor

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    Wang WX

    2016-01-01

    Full Text Available Wenxian Wang,1 Xiaowen Jiang,1 Zhengbo Song,1,2 Yiping Zhang1,2 1Department of Chemotherapy, Zhejiang Cancer Hospital, 2Key Laboratory Diagnosis and Treatment Technology on Thoracic Oncology, Hangzhou, Zhejiang, People’s Republic of China Abstract: Anaplastic lymphoma kinase (ALK rearrangement lung cancer responds to ALK tyrosine kinase inhibitors. It is known that many cases ultimately acquired resistance to crizotinib. However, a case of primary resistance is rare. We present a case of harboring exon 19 deletion in epidermal growth factor receptor in ALK rearranged lung adenocarcinoma, who experienced a partial tumor response to icotinib after failure with crizotinib therapy and chemotherapy. Considering the partial response, we conclude that it is important to find the cause of resistance to crizotinib. We detected gene mutations with plasma by the next-generation sequencing; the next-generation sequencing demonstrates an attractive system to identify mutations improving the outcome of patients with a deadly disease. Keywords: non-small cell lung cancer, anaplastic lymphoma kinase, crizotinib, epidermal growth factor receptor

  16. [Ecology-economy harmonious development based on the ecological services value change in Yanqi Basin, Northwest China].

    Science.gov (United States)

    Mamat, Zulpiya; Halik, Umut; Aji, Rouzi; Nurmemet, Ilyas; Anwar, Mirigul; Keyimu, Maierdang

    2015-03-01

    In this paper, we used land use/cover ecosystem service value estimation model and ecological economic coordination degree model to analyze the changes of the ecosystem service value by the land use/cover changes during 1985, 1990, 1996, 2000, 2005 and 2011 in Yanqi Basin, Xin-jiang. Then we evaluated the ecology-economy harmony and the regional differences. The results showed that during 1985-2011, there was an increasing trend in the areas of waters, wetland, sand, cultivated land and construction land in Yanqi Basin. In contrast, that of the saline-alkali land, grassland and woodland areas exhibited a decreasing trend. The ecosystem service value in Yanqi Basin during this period presented an increasing trend, among which the waters and cultivated land contributed most to the total value of ecosystem services, while the grassland and the woodland had obviously declined contribution to the total value of ecosystem services. The research showed that the development of ecological economy in the study area was at a low conflict and low coordination level. So, taking reasonable and effective use of the regional waters and soil resources is the key element to maintain the ecosystem service function and sustainable and harmonious development of economy in Yanqi Basin.

  17. Analysis of technologies and economics for geothermal energy utilization of electric power plant

    International Nuclear Information System (INIS)

    Haijie, C.

    1993-01-01

    Geothermal energy -- it is a kind of heat energy which pertains to the internal heat of the earth. It carries the heat of the earth outward by the underground water of the rock section of the earth. Normally, the temperature of the thermal water is 50 degrees-140 degrees. During the 20th century, the rapid development of industry and agriculture quickly increased the need for large amounts of electric power. Now, although there are coal power plants, oil and nature gas power plants, hydroelectric power and nuclear power plants, all countries of the world attach importance to the prospect of geothermal power plants. It is the most economic (no consumption fuel) and safe (no pollution) power plant. (Present author considered that the chlorofluorocarbon refrigerants such as RII, R12, and etc. are not used). In 1904, Italy established the first geothermal power plant in the world. Soon afterwards, the U.S.A., Iceland, Japan, Russia, and New Zealand also established geothermal power plants. In 1970, China, North China, Jiang province and Guangdong province also established geothermal power plants. In 1975, the U.S.A. geothermal power plant capacity of 522mw was the first in the world

  18. Fitting of full Cobb-Douglas and full VRTS cost frontiers by solving goal programming problem

    Science.gov (United States)

    Venkateswarlu, B.; Mahaboob, B.; Subbarami Reddy, C.; Madhusudhana Rao, B.

    2017-11-01

    The present research article first defines two popular production functions viz, Cobb-Douglas and VRTS production frontiers and their dual cost functions and then derives their cost limited maximal outputs. This paper tells us that the cost limited maximal output is cost efficient. Here the one side goal programming problem is proposed by which the full Cobb-Douglas cost frontier, full VRTS frontier can be fitted. This paper includes the framing of goal programming by which stochastic cost frontier and stochastic VRTS frontiers are fitted. Hasan et al. [1] used a parameter approach Stochastic Frontier Approach (SFA) to examine the technical efficiency of the Malaysian domestic banks listed in the Kuala Lumpur stock Exchange (KLSE) market over the period 2005-2010. AshkanHassani [2] exposed Cobb-Douglas Production Functions application in construction schedule crashing and project risk analysis related to the duration of construction projects. Nan Jiang [3] applied Stochastic Frontier analysis to a panel of New Zealand dairy forms in 1998/99-2006/2007.

  19. The advertisement calls of Quasipaa shini (Ahl, 1930) (Anura: Dicroglossidae).

    Science.gov (United States)

    Kong, Shen Shen; Zheng, Rong Quan; Zhang, Qi Peng

    2016-12-04

    The genus Quasipaa (Family Dicroglossidae) is currently composed of 11 species distributed in China and Southeast Asia: Quasipaa acanthophora (Dubois & Ohler 2009), Q. boulengeri (Günther 1889), Q. courtoisi (Angel 1922), Q. delacouri (Angel 1928), Q. exilispinosa (Liu & Hu, 1975), Q. fasciculispina (Inger 1970), Q. jiulongensis (Huang & Liu, 1985), Q. shini (Ahl 1930), Q. spinosa (David 1875), Q. verrucospinosa (Bourret 1937), Q. yei (Chen, Qu & Jiang 2002) (Frost 2016). These species are morphologically similar, and their taxonomy is subject to controversy (Che et al. 2009). Analyses of nuclear and mitochondrial genes suggest the genus likely encompass additional cryptic species (Ye et al. 2013). Bioacoustics has contributed to studies on the taxonomy of the genus (Ye et al. 2013; Shen et al. 2015), however, to date, only the advertisement calls of Q. spinosa are known (Yu & Zheng 2009; Chen et al. 2012; Shen et al. 2015). Here, we describe the advertisement calls of Q. shini, which inhabits streams in the southern part of central China(Guizhou, Hunan, Guangxi and Jiangxi) and is characterized by the presence of keratinized skin spines on the lateral surfaces of the body.

  20. Estimating Total Discharge in the Yangtze River Basin Using Satellite-Based Observations

    Directory of Open Access Journals (Sweden)

    Samuel A. Andam‑Akorful

    2013-07-01

    Full Text Available The measurement of total basin discharge along coastal regions is necessary for understanding the hydrological and oceanographic issues related to the water and energy cycles. However, only the observed streamflow (gauge-based observation is used to estimate the total fluxes from the river basin to the ocean, neglecting the portion of discharge that infiltrates to underground and directly discharges into the ocean. Hence, the aim of this study is to assess the total discharge of the Yangtze River (Chang Jiang basin. In this study, we explore the potential response of total discharge to changes in precipitation (from the Tropical Rainfall Measuring Mission—TRMM, evaporation (from four versions of the Global Land Data Assimilation—GLDAS, namely, CLM, Mosaic, Noah and VIC, and water-storage changes (from the Gravity Recovery and Climate Experiment—GRACE by using the terrestrial water budget method. This method has been validated by comparison with the observed streamflow, and shows an agreement with a root mean square error (RMSE of 14.30 mm/month for GRACE-based discharge and 20.98 mm/month for that derived from precipitation minus evaporation (P − E. This improvement of approximately 32% indicates that monthly terrestrial water-storage changes, as estimated by GRACE, cannot be considered negligible over Yangtze basin. The results for the proposed method are more accurate than the results previously reported in the literature.

  1. Prediction of Near-Field Wave Attenuation Due to a Spherical Blast Source

    Science.gov (United States)

    Ahn, Jae-Kwang; Park, Duhee

    2017-11-01

    Empirical and theoretical far-field attenuation relationships, which do not capture the near-field response, are most often used to predict the peak amplitude of blast wave. Jiang et al. (Vibration due to a buried explosive source. PhD Thesis, Curtin University, Western Australian School of Mines, 1993) present rigorous wave equations that simulates the near-field attenuation to a spherical blast source in damped and undamped media. However, the effect of loading frequency and velocity of the media have not yet been investigated. We perform a suite of axisymmetric, dynamic finite difference analyses to simulate the propagation of stress waves induced by spherical blast source and to quantify the near-field attenuation. A broad range of loading frequencies, wave velocities, and damping ratios are used in the simulations. The near-field effect is revealed to be proportional to the rise time of the impulse load and wave velocity. We propose an empirical additive function to the theoretical far-field attenuation curve to predict the near-field range and attenuation. The proposed curve is validated against measurements recorded in a test blast.

  2. State and Smuggling in Modern China: The Case of Guangzhouwan/Zhanjiang

    Directory of Open Access Journals (Sweden)

    Steven Pieragastini

    2017-12-01

    Full Text Available The Leizhou Peninsula in western Guangdong (concurrent with the present-day municipality of Zhanjiang has at several points in history been an important site of exchange, both licit and illicit in the eyes of central authorities. The French gained control of the area from the weakened Qing government in 1898–1899 and established their “leased territory” of Guangzhouwan. Administered as part of French Indochina, Guangzhouwan became a fiefdom of smugglers, pimps, and pirates, never developing into the rival to Hong Kong that the French hoped it would become. After a brief Japanese occupation, the French returned the leased territory to the government of Chiang Kai-shek (Jiang Jieshi after World War II, but their colonial presence left a legacy of trafficking, violence, and anti-imperialism that emboldened Communist guerrillas in the area. Once the Communists came into power in 1949, they subjected Zhanjiang and other liminal spaces along the Chinese coast to vigorous anti-smuggling and anti-drug campaigns. But a return to smuggling in the Reform Era (1978–present suggests that the successful repression of smuggling in the Mao era may have been a temporary exception to the historical rule in this region.

  3. Mitochondrial phylogeny of Chinese barred species of the cyprinid genus Acrossocheilus Oshima, 1919 (Teleostei: Cypriniformes) and its taxonomic implications.

    Science.gov (United States)

    Yuan, Le-Yang; Liu, Xiao-Xiang; Zhang, E

    2015-12-21

    Sequences from the mitochondrial control region of 14 putative species of Acrossocheilus (Cyprinidae) were examined to elucidate phylogenetic relationships within species of the barred group in that genus. Phylogenetic reconstructions were generated using three tree-building methods: maximum parsimony, maximum likelihood, and Bayesian inference. The resultant phylogenies were consistent with monophyly of the majority of the morphologically recognized species. However, mitochondrial DNA sequence evidence is incongruent with monophyly of A. fasciatus, as currently conceived. This species occurs only in the upper Qiantang-Jiang basin in Zhejiang and Anhui provinces, and coastal rivers in the Zhejiang Province. The species formerly recognized as A. paradoxus from Zhejiang Province is A. fasciatus. The specimens previously reported as A. fasciatus from river basins in Fujian Province are misidentified A. wuyiensis. The barred group of Acrossocheilus is shown to be polyphyletic. Acrossocheilus is restricted to the barred species here placed in "Clade II," containing A. paradoxus and relatives. Separate generic status is recommended for A. monticola and for A. longipinnis and their closest relatives, although more information on phylogenetic relationships based on multiple genes is required to develop robust phylogenetic hypotheses and diagnoses. Masticbarbus Tang, 1942 is available for A. longipinnis and three allied species (A. iridescens, A. microstomus and A. lamus).

  4. Systematics of the east Palaearctic pear psyllids (Hemiptera: Psylloidea) with particular focus on the Japanese and Korean fauna.

    Science.gov (United States)

    Cho, Geonho; Burckhardt, Daniel; Inoue, Hiromitsu; Luo, Xinyu; Lee, Seunghwan

    2017-12-04

    The confused taxonomy of the east Palaearctic pear psyllids, serious pests on cultivated pear, is reviewed. Fifty-six nominal species have been reported from Pyrus, 25 of which we consider valid and ten as not being associated with Pyrus. Our taxonomic revision suggests that, in Korea, four Cacopsylla species develop on pear: the univoltine C. burckhardti Luo et al. previously misidentified as C. pyrisuga (Foerster), the polyvoltine, seasonally dimorphic C. jukyungi (Kwon) (winter form 'cinereosignata' Luo et al., summer form 'jukyungi'), commonly found in Korean pear orchards, and C. maculatili Li (winter form 'maculatili', summer form 'qiuzili' Li) previously misidentified as C. pyricola (Foerster) by some authors, as well as the probably polyvoltine but not dimorphic C. sandolbaea (Park & Lee). The former three species (C. burckhardti, C. jukyungi, misidentified as C. chinensis (Yang & Li), and C. maculatili) occur also in Japan. Keys to the adult and fifth instar immatures as well as short biological notes are provided, and C. jukyungi and C. sandolbaea are redescribed. Following nomenclatorial changes are proposed: Cacopsylla betulaefoliae (Yang & Li, 1981) = Psylla heterobetulaefoliae Yang & Li, 1981, syn. nov.; Cacopsylla bidens (Šulc, 1907) = Psylla jiangli Yang & Li, 1981, syn. nov.; Cacopsylla jukyungi (Kwon) = C. cinereosignata Luo et al., syn. nov.; Cacopsylla maculatili Li = C. qiuzili Li, syn. nov.; Cacopsylla nigella (Konovalova), comb. nov. from Psylla. The synonymy of P. obongsana Kwon with C. sandolbaea is confirmed.

  5. Impact of strabismus on the quality of life of Chinese Han teenagers

    Directory of Open Access Journals (Sweden)

    Tu CS

    2016-06-01

    Full Text Available Changsen Tu, Liang Ye, Longfei Jiang, Yuwen Wang, Yingzi Li The Eye Hospital of Wenzhou Medical University, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, People’s Republic of China Background: Although much research has been conducted on the impact of strabismus on the quality of life (QoL of adults, the effect of this condition on teenagers has not been extensively studied. This study therefore aimed to assess the effect of strabismus on the vision-related QoL of Chinese teenagers.Methods: The Chinese version of the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25 was self-administered by 1,040 teenagers with strabismus and 1,002 individuals with normal vision. All the participants were from the Chinese Han population. The independent samples t-test was used to compare QoL between teenagers with and without strabismus.Results: The majority of scores on the NEI-VFQ-25 domains were significantly different between the two groups. QoL was significantly lower in individuals with strabismus compared with teenagers with normal vision on all domains, with the exception of social functioning.Conclusion: Statistically significantly lower vision-related QoL scores were found in Chinese Han teenagers with strabismus compared with those without strabismus. Keywords: quality of life, strabismus, NEI-VFQ-25, teenager, HRQoL

  6. RESOLVING THE STRUCTURE AND KINEMATICS OF THE BN OBJECT AT 0.''2 RESOLUTION

    International Nuclear Information System (INIS)

    Rodriguez, Luis F.; Zapata, Luis A.; Ho, Paul T. P.

    2009-01-01

    We present sensitive 7 mm observations of the H53α recombination line and adjacent continuum, made toward the Orion BN/KL region. In the continuum we detect the BN object, the radio source I (GMR I) and the radio counterpart of the infrared (IR) source n (Orion-n). Comparing with observations made at similar angular resolutions but lower frequency, we discuss the spectral indices and angular sizes of these sources. In the H53α line, we only detect the BN object. This is the first time that radio recombination lines have been detected from this source. The LSR radial velocity of BN from the H53α line, v LSR = 20.1 ± 2.1 km s -1 , is consistent with that found from previous studies in near-IR lines. While the continuum emission is expected to have considerable optical depth at 7 mm, the observed H53α line emission is consistent with an optically thin nature and we discuss possible explanations for this apparent discrepancy. There is evidence of a velocity gradient, with the NE part of BN being redshifted by ∼10 km s -1 with respect to the SW part. This is consistent with the suggestion of Jiang et al. that BN may be driving an ionized outflow along that direction.

  7. Signatures of shell evolution in alpha decay across the N = 126 shell closure

    Science.gov (United States)

    Rui-Wang; Wang, Rui-Yao; Qian, Yi-Bin; Ren, Zhong-Zhou

    2017-06-01

    Within the alpha-cluster model, we particularly investigate the alpha decay of exotic nuclei in the vicinity of the N = 126 neutron shell plus the Z = 82 proton shell. The systematics of alpha-preformation probability (P α ), as an indicator of the shell effect, is deduced from the ratio of the experimental decay width to the calculated one. Through the comparative analysis of the P α trend in the N = 124-130 isotonic chain, the N = 126 and Z = 82 shell closures are believed to strongly affect the formation of the alpha particle before its penetration. Additionally, the P α variety in Po and Rn isotopes is presented as another proof for such an influence. More importantly, it may be concluded that the expected neutron (or proton) shell effect gradually fades away along with the increasing valence proton (or neutron) number. The odd-even staggering presented in the P α value is also discussed. Supported by National Natural Science Foundation of China (11375086, 11535004, 11605089, 11120101005), Natural Science Youth Fund of Jiangsu Province (BK20150762), Fundamental Research Funds for the Central Universities (30916011339), 973 National Major State Basic Research and Development Program of China (2013CB834400), and a Project Funded by the Priority Academic Programme Development of JiangSu Higher Education Institutions (PAPD)

  8. Preliminary results of Sr:Ca ratios of Coilia nasus in otoliths by micro-PIXE

    International Nuclear Information System (INIS)

    Zhong, L.; Guo, H.; Shen, H.; Li, X.; Tang, W.; Liu, J.; Jin, J.; Mi, Y.

    2007-01-01

    Coilia nasus, distributed in Changjiang River as well as northwest Pacific, has a high economic value owing to its delicacy and nutritional value. Recently, the fishing yields in Changjiang River have decreased dramatically due to excessive fishing and changes in the aquatic ecology. In order to prevent excessive fishing effectively, the life history pattern of C. nasus should be known in detail. Ootoliths contain much information about a fish's life history, because elemental concentrations remain unaltered after deposition, and can be analysed. C. nasus collected from Jing Jiang (lower reaches of the Changjiang River) and Jiu Duan Sha (the estuary of the Changjiang River) were studied by measuring Sr:Ca ratios in their otoliths using micro-PIXE. On average, the Sr:Ca ratios of estuarine C. nasus were found to be higher. The Sr:Ca ratios were higher in the core regions and lower in the outermost marginal regions, and shows fluctuations in certain regions. Possible corresponding life history patterns are discussed

  9. La solución de problemas cognitivos. Una reflexión cognitiva sociocultural

    Directory of Open Access Journals (Sweden)

    Rosalía Montealegre

    2010-07-01

    Full Text Available El objetivo de esta investigación fue revisar la producción científica sobre suicidio en la población infantil, mediante un análisis bibliométrico de los artículos publicados durante el período 1985-2005, en las bases de datos Lilacs, Medline, Ebsco Host y Ovid. El número de artículos revisados fue 84, siendo Estados Unidos el país de mayor producción con un 65,85% de los trabajos publicados. Casi el total de los artículos se encuentran firmados por uno, dos o tres autores; los autores más productivos son Shaffer, King, Kazdin, Jiang, Rosenbaum, Bridge, Axelson, Brent, Ryan y Mann cada uno con dos trabajos publicados y Pfeffer con un total de cuatro artículos. Los contenidos más comunes son los de revisión teórica del suicidio en niños (conceptualización, suicidio consumado, ideación suicida e intención suicida y evaluación de suicidio en esta población.

  10. Análisis bibliométrico de la producción científica sobre suicidio en niños en el periodo 1985-2005

    Directory of Open Access Journals (Sweden)

    Ximena Palacios Espinosa

    2010-07-01

    Full Text Available El objetivo de esta investigación fue revisar la producción científica sobre suicidio en la población infantil, mediante un análisis bibliométrico de los artículos publicados durante el período 1985-2005, en las bases de datos Lilacs, Medline, Ebsco Host y Ovid. El número de artículos revisados fue 84, siendo Estados Unidos el país de mayor producción con un 65,85% de los trabajos publicados. Casi el total de los artículos se encuentran firmados por uno, dos o tres autores; los autores más productivos son Shaffer, King, Kazdin, Jiang, Rosenbaum, Bridge, Axelson, Brent, Ryan y Mann cada uno con dos trabajos publicados y Pfeffer con un total de cuatro artículos. Los contenidos más comunes son los de revisión teórica del suicidio en niños (conceptualización, suicidio consumado, ideación suicida e intención suicida y evaluación de suicidio en esta población.

  11. in Search of Leaders with Chinesecharacteristics: A Reflection of Indonesia's 2014 General Election

    Directory of Open Access Journals (Sweden)

    Abdullah Dahana

    2016-04-01

    Full Text Available Article dealt with the questions of leadership transition in post–Mao Zedong/Deng Xiaoping era. During the time of Mao and Deng, factionalism played important roles in all segments of Chinese politics, including the election of a leader. After Mao and Deng, although factionalism persisted, it did not become contradiction, but rather it created a situation in which factions within the Chinese Communist Party (CCP cooperated in all aspects of Chinese politics. The main objective of this research was the perpetuation of the party’s grip on political power . The article also dealt with the questions of recruiting and educating party cadres. Career paths of three post-Deng Chinese leaders, i.e., Jiang Zemin, Hu Jintao, and Xi Jinping were also explored to explain the period they reached their peak of their careers by blood and sweat. This article finds that it cannot be denied that what is happening in China now in the area of leadership is using a system of a political dynasty. 

  12. Specific features of acute stroke in the Russian Federation and in the People’s Republic of China (according to the data of some big stroke units

    Directory of Open Access Journals (Sweden)

    S. S. Yu

    2016-01-01

    Full Text Available The study focuses on comparison and analysis of the work of big stroke units in the Russian Federation and the People’s Republic of China specialized in the medical care for patients with acute stroke. 522 patients were surveyed in Russia’s and China’s regional stroke units. In the Russian Federation, patients being treated in the «City Hospital No.26» (SaintPetersburg took part in the study. In China patients of the First Affiliated Hospital of the Chongqing Medical University, Central Hospital Jiang jin, Regional People’s Hospital Yubei district, Regional People’s Hospital Bishan (Chongqing Province. The analysis of differences was performed by the following parameters: personality traits, age, gender, level of education, income, health insurance category, profession, employment, professional activities over the last year, place of residence of the patient, features of the stroke, time during the first symptoms of stroke to hospitalization, kinds of medical services, the main risk factors and value of prevention before stroke.

  13. Dynamics of processing invisible faces in the brain: automatic neural encoding of facial expression information.

    Science.gov (United States)

    Jiang, Yi; Shannon, Robert W; Vizueta, Nathalie; Bernat, Edward M; Patrick, Christopher J; He, Sheng

    2009-02-01

    The fusiform face area (FFA) and the superior temporal sulcus (STS) are suggested to process facial identity and facial expression information respectively. We recently demonstrated a functional dissociation between the FFA and the STS as well as correlated sensitivity of the STS and the amygdala to facial expressions using an interocular suppression paradigm [Jiang, Y., He, S., 2006. Cortical responses to invisible faces: dissociating subsystems for facial-information processing. Curr. Biol. 16, 2023-2029.]. In the current event-related brain potential (ERP) study, we investigated the temporal dynamics of facial information processing. Observers viewed neutral, fearful, and scrambled face stimuli, either visibly or rendered invisible through interocular suppression. Relative to scrambled face stimuli, intact visible faces elicited larger positive P1 (110-130 ms) and larger negative N1 or N170 (160-180 ms) potentials at posterior occipital and bilateral occipito-temporal regions respectively, with the N170 amplitude significantly greater for fearful than neutral faces. Invisible intact faces generated a stronger signal than scrambled faces at 140-200 ms over posterior occipital areas whereas invisible fearful faces (compared to neutral and scrambled faces) elicited a significantly larger negative deflection starting at 220 ms along the STS. These results provide further evidence for cortical processing of facial information without awareness and elucidate the temporal sequence of automatic facial expression information extraction.

  14. Evaluation of the odour reduction potential of alternative cover materials at a commercial landfill.

    Science.gov (United States)

    Solan, P J; Dodd, V A; Curran, T P

    2010-02-01

    The availability of virgin soils and traditional landfill covers are not only costly and increasingly becoming scarce, but they also reduce the storage capacity of landfill. The problem can be overcome by the utilisation of certain suitable waste streams as alternative landfill covers. The objective of this study was to assess the suitability of Construction & Demolition fines (C&D), Commercial & Industrial fines (C&I) and woodchip (WC) as potential landfill cover materials in terms of odour control. Background odour analysis was conducted to determine if any residual odour was emitted from the cover types. It was deemed negligible for the three materials. The odour reduction performance of each of the materials was also examined on an area of an active landfill site. A range of intermediate cover compositions were also studied to assess their performance. Odour emissions were sampled using a Jiang hood and analysed. Results indicate that the 200 mm deep combination layer of C&D and wood chip used on-site is adequate for odour abatement. The application of daily cover was found to result in effective reduction allowing for the background odour of woodchip.

  15. A large and aggressive fibromatosis in the axilla: a rare case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Duan M

    2018-05-01

    Full Text Available Mingyue Duan,1 Hua Xing,1 Keren Wang,1 Chunbo Niu,2 Chengwei Jiang,2 Lijuan Zhang,1 Shereen Ezzat,3 Le Zhang1 1Department of Breast Surgery, China-Japan Union Hospital, Jilin University, Changchun, Jilin, People’s Republic of China; 2Department of Pathology, China-Japan Union Hospital, Jilin University, Changchun, Jilin, People’s Republic of China; 3Ontario Cancer Institute and The Endocrine Oncology Site Group, Princess Margaret Hospital, University Health Network, Toronto, ON, Canada Abstract: Aggressive fibromatosis (AF is a rare benign tumor, which occurs in the deep part of bone and muscle fibrous tissue. Clinical and pathological features can be challenging for definitive diagnosis. Here, we report a rare case of a large AF in the axilla. Interestingly, 18 F-fluorodeoxyglucose-positron emission tomography/computed tomography showed significant increase in standard uptake value. Surgical resection yielded a spindle cell tumor likely of fibromatosis origin which was positive for β-catenin expression. Keywords: aggressive fibromatosis, desmoid-type fibromatosis, axilla, 18 F-fluorodeoxyglucose, PET/CT, β-catenin

  16. Giant electrocaloric response in the prototypical Pb(Mg,Nb)O3 relaxor ferroelectric from atomistic simulations

    Science.gov (United States)

    Jiang, Zhijun; Nahas, Y.; Prokhorenko, S.; Prosandeev, S.; Wang, D.; Íñiguez, Jorge; Bellaiche, L.

    2018-03-01

    An atomistic effective Hamiltonian is used to investigate electrocaloric (EC) effects of Pb (Mg1 /3Nb2 /3) O3 relaxor ferroelectrics in its ergodic regime, and subject to electric fields applied along the pseudocubic [111] direction. Such a Hamiltonian qualitatively reproduces (i) the electric field-versus-temperature phase diagram, including the existence of a critical point where first-order and second-order transitions meet each other; and (ii) a giant EC response near such a critical point. It also reveals that such giant response around this critical point is microscopically induced by field-induced percolation of polar nanoregions. Moreover, it is also found that, for any temperature above the critical point, the EC coefficient-versus-electric-field curve adopts a maximum (and thus larger electrocaloric response too), that can be well described by the general Landau-like model proposed by Jiang et al., [Phys. Rev. B 96, 014114 (2017)], 10.1103/PhysRevB.96.014114, and that is further correlated with specific microscopic features related to dipoles lying along different rhombohedral directions. Furthermore, for temperatures being at least 40 K higher than the critical temperature, the (electric field, temperature) line associated with this maximal EC coefficient is below both the Widom line and the line representing percolation of polar nanoregions.

  17. From Foreground to Background: How Task-Neutral Context Influences Contextual Cueing of Visual Search.

    Science.gov (United States)

    Zang, Xuelian; Geyer, Thomas; Assumpção, Leonardo; Müller, Hermann J; Shi, Zhuanghua

    2016-01-01

    Selective attention determines the effectiveness of implicit contextual learning (e.g., Jiang and Leung, 2005). Visual foreground-background segmentation, on the other hand, is a key process in the guidance of attention (Wolfe, 2003). In the present study, we examined the impact of foreground-background segmentation on contextual cueing of visual search in three experiments. A visual search display, consisting of distractor 'L's and a target 'T', was overlaid on a task-neutral cuboid on the same depth plane (Experiment 1), on stereoscopically separated depth planes (Experiment 2), or spread over the entire display on the same depth plane (Experiment 3). Half of the search displays contained repeated target-distractor arrangements, whereas the other half was always newly generated. The task-neutral cuboid was constant during an initial training session, but was either rotated by 90° or entirely removed in the subsequent test sessions. We found that the gains resulting from repeated presentation of display arrangements during training (i.e., contextual-cueing effects) were diminished when the cuboid was changed or removed in Experiment 1, but remained intact in Experiments 2 and 3 when the cuboid was placed in a different depth plane, or when the items were randomly spread over the whole display but not on the edges of the cuboid. These findings suggest that foreground-background segmentation occurs prior to contextual learning, and only objects/arrangements that are grouped as foreground are learned over the course of repeated visual search.

  18. Visual search and contextual cueing: differential effects in 10-year-old children and adults.

    Science.gov (United States)

    Couperus, Jane W; Hunt, Ruskin H; Nelson, Charles A; Thomas, Kathleen M

    2011-02-01

    The development of contextual cueing specifically in relation to attention was examined in two experiments. Adult and 10-year-old participants completed a context cueing visual search task (Jiang & Chun, The Quarterly Journal of Experimental Psychology, 54A(4), 1105-1124, 2001) containing stimuli presented in an attended (e.g., red) and unattended (e.g., green) color. When the spatial configuration of stimuli in the attended and unattended color was invariant and consistently paired with the target location, adult reaction times improved, demonstrating learning. Learning also occurred if only the attended stimuli's configuration remained fixed. In contrast, while 10 year olds, like adults, showed incrementally slower reaction times as the number of attended stimuli increased, they did not show learning in the standard paradigm. However, they did show learning when the ratio of attended to unattended stimuli was high, irrespective of the total number of attended stimuli. Findings suggest children show efficient attentional guidance by color in visual search but differences in contextual cueing.

  19. Object-based implicit learning in visual search: perceptual segmentation constrains contextual cueing.

    Science.gov (United States)

    Conci, Markus; Müller, Hermann J; von Mühlenen, Adrian

    2013-07-09

    In visual search, detection of a target is faster when it is presented within a spatial layout of repeatedly encountered nontarget items, indicating that contextual invariances can guide selective attention (contextual cueing; Chun & Jiang, 1998). However, perceptual regularities may interfere with contextual learning; for instance, no contextual facilitation occurs when four nontargets form a square-shaped grouping, even though the square location predicts the target location (Conci & von Mühlenen, 2009). Here, we further investigated potential causes for this interference-effect: We show that contextual cueing can reliably occur for targets located within the region of a segmented object, but not for targets presented outside of the object's boundaries. Four experiments demonstrate an object-based facilitation in contextual cueing, with a modulation of context-based learning by relatively subtle grouping cues including closure, symmetry, and spatial regularity. Moreover, the lack of contextual cueing for targets located outside the segmented region was due to an absence of (latent) learning of contextual layouts, rather than due to an attentional bias towards the grouped region. Taken together, these results indicate that perceptual segmentation provides a basic structure within which contextual scene regularities are acquired. This in turn argues that contextual learning is constrained by object-based selection.

  20. Estimating actual evapotranspiration from remote sensing imagery using R: the package 'TriangleMethod'.

    Science.gov (United States)

    Gampe, David; Huber García, Verena; Marzahn, Philip; Ludwig, Ralf

    2017-04-01

    Actual evaporation (Eta) is an essential variable to assess water availability, drought risk and food security, among others. Measurements of Eta are however limited to a small footprint, hampering a spatially explicit analysis and application and are very often not available at all. To overcome the problem of data scarcity, Eta can be assessed by various remote sensing approaches such as the Triangle Method (Jiang & Islam, 1999). Here, Eta is estimated by using the Normalized Difference Vegetation Index (NDVI) and land surface temperature (LST). In this study, the R-package 'TriangleMethod' was compiled to efficiently perform the calculations of NDVI and processing LST to finally derive Eta from the applied data set. The package contains all necessary calculation steps and allows easy processing of a large data base of remote sensing images. By default, the parameterization for the Landsat TM and ETM+ sensors are implemented, however, the algorithms can be easily extended to additional sensors. The auxiliary variables required to estimate Eta with this method, such as elevation, solar radiation and air temperature at the overpassing time, can be processed as gridded information to allow for a better representation of the study area. The package was successfully applied in various studies in Spain, Palestine, Costa Rica and Canada.

  1. Robust and efficient biometrics based password authentication scheme for telecare medicine information systems using extended chaotic maps.

    Science.gov (United States)

    Lu, Yanrong; Li, Lixiang; Peng, Haipeng; Xie, Dong; Yang, Yixian

    2015-06-01

    The Telecare Medicine Information Systems (TMISs) provide an efficient communicating platform supporting the patients access health-care delivery services via internet or mobile networks. Authentication becomes an essential need when a remote patient logins into the telecare server. Recently, many extended chaotic maps based authentication schemes using smart cards for TMISs have been proposed. Li et al. proposed a secure smart cards based authentication scheme for TMISs using extended chaotic maps based on Lee's and Jiang et al.'s scheme. In this study, we show that Li et al.'s scheme has still some weaknesses such as violation the session key security, vulnerability to user impersonation attack and lack of local verification. To conquer these flaws, we propose a chaotic maps and smart cards based password authentication scheme by applying biometrics technique and hash function operations. Through the informal and formal security analyses, we demonstrate that our scheme is resilient possible known attacks including the attacks found in Li et al.'s scheme. As compared with the previous authentication schemes, the proposed scheme is more secure and efficient and hence more practical for telemedical environments.

  2. Análisis bibliométrico de la producción científica sobre suicidio en niños en el período 1985-2005

    Directory of Open Access Journals (Sweden)

    Angela María Barrera Lora

    2007-06-01

    Full Text Available producción científica sobre suicidio en la población infantil, mediante un análisis bibliométrico de los artículos publicados durante el período 1985-2005, en las bases de datos Lilacs, Medline, Ebsco Host y Ovid. El número de artículos revisados fue 84, siendo Estados Unidos el país de mayor producción con un 65,85% de los trabajos publicados. Casi el total de los artículos se encuentran firmados por uno, dos o tres autores; los autores más productivos son Shaffer, King, Kazdin, Jiang, Rosenbaum, Bridge, Axelson, Brent, Ryan y Mann cada uno con dos trabajos publicados y Pfeffer con un total de cuatro artículos. Los contenidos más comunes son los de revisión teórica del suicidio en niños (conceptualización, suicidio consumado, ideación suicida e intención suicida y evaluación de suicidio en esta población.

  3. Information-entropic method for studying the stability bound of nonrelativistic polytropic stars within modified gravity theories

    Science.gov (United States)

    Wibisono, C.; Sulaksono, A.

    We study the stability of nonrelativistic polytropic stars within two modified gravity theories, i.e. beyond Horndeski gravity and Eddington-inspired Born-Infeld theories, using the configuration entropy method. We use the spatially localized bounded function of energy density as solutions from stellar effective equations to construct the corresponding configuration entropy. We use the same argument as the one used by Gleiser and coworkers [M. Gleiser and D. Sowinski, Phys. Lett. B 727 (2013) 272; M. Gleiser and N. Jiang, Phys. Rev. D 92 (2015) 044046] that the stars are stable if there is a peak in configuration entropy as a function of adiabatic index curve. Specifically, the boundary between stable and unstable regions which corresponds to Chandrasekhar stability bound is indicated from the existence of the maximum peak while the most stable polytropic stars are indicated by the minimum peak in the corresponding curve. We have found that the values of critical adiabatic indexes of Chandrasekhar stability bound and the most stable polytropic stars predicted by the nonrelativistic limits of beyond Horndeski gravity and Eddington-inspired Born-Infeld theories are different to those predicted by general relativity where the corresponding differences depend on the free parameters of both theories.

  4. VizieR Online Data Catalog: HD 163151: a new W UMa type system (Rodriguez+ 1998)

    Science.gov (United States)

    Rodríguez, E.; Claret, A.; García, J. M.; Zerbi, F. M.; Garrido, R.; Martín, S.; Akan, C.; Luedeke, K.; Keskin, V.; Ibanoglu, C.; Evren, S.; Tunca, Z.; Pekunlu, R.; Paparo, M.; Nuspl, J.; Krisciunas, K.; Jiang, S. Y.

    1998-06-01

    Table 2 contains 408 simultaneous measurements collected in each of the four uvby colours of the Stromgren photometric system for the W UMa system HD 163151. The data are magnitude differences (Du, Dv, Db, Dy, D(b-y), Dm1, Dc1) of the variable star minus comparison star in the standard system versus Heliocentric Julian Day. Tables 3, 4 and 5 are the same, but for Hβ (65 points), Johnson B data (212 points) and Johnson V data (355 points). The comparison star is HD 166095. The origin in time is the Julian Day 2449858. The observations were carried out (by E. Rodriguez, A. Claret, J.M. Garcia, F.M. Zerbi, R. Garrido, S. Martin, C. Akan, K. Luedeke, V. Keskin, C. Ibanoglu, S. Evren, Z. Tunca, R. Pekunlu, M. Paparo, J. Nuspl, K. Krisciunas and S.Y. Jiang) in 1995 during the course of a multisite campaign. The following telescopes were used: 90cm telescope of the Sierra Nevada Observatory, Spain (uvby-Hβ photometry); 50cm telescope at the Ege University Observatory, Turkey (BV-uvby); 50cm telescope at Piszkesteto mountain station, Konkoly Observatory, Hungary (BV); 50cm telescope at the Merate Observatory, Italy (V); 30cm telescope at Albuquerque, New Mexico, USA (V) and 15cm telescope at Mauna Kea, Hawaii, USA (V). (4 data files).

  5. Understanding the “New Confucianism”: Reinventing Confucianism and the Future of China

    Directory of Open Access Journals (Sweden)

    André Bueno

    2016-05-01

    Full Text Available This article focuses on an important change in Chinese thinking of the 20th century: the rebirth of Confucianism as the intellectual movement called “New Confucianism” which is considered in the China of today to be a possible substitute for Marxist ideology. But what exactly is the “New Confucianism”? The author first attempts to highlight the definition of Confucianism from the Western perspective and the problems that arise in that process. The study is based primarily on the work of Jiang Qing 蒋庆, one of the principal thinkers of this movement of ideas, and on the analysis of the main western interpreter of Qing, researcher Daniel Bell. Further along, the paper discusses some of the most common tags of this movement: New Confucianism as a religion, as a social doctrine, and as a new political option for the future. Notwithstanding the elusiveness of the concept it appears to be the case that this movement is developing spontaneously in modern Chinese society and is gaining more and more followers, even via a lighter literary genre through which modified Confucian thoughts and tips for coping with everyday life can approach a wider crowd.

  6. Assessment of Reservoir Water Quality Using Multivariate Statistical Techniques: A Case Study of Qiandao Lake, China

    Directory of Open Access Journals (Sweden)

    Qing Gu

    2016-03-01

    Full Text Available Qiandao Lake (Xin’an Jiang reservoir plays a significant role in drinking water supply for eastern China, and it is an attractive tourist destination. Three multivariate statistical methods were comprehensively applied to assess the spatial and temporal variations in water quality as well as potential pollution sources in Qiandao Lake. Data sets of nine parameters from 12 monitoring sites during 2010–2013 were obtained for analysis. Cluster analysis (CA was applied to classify the 12 sampling sites into three groups (Groups A, B and C and the 12 monitoring months into two clusters (April-July, and the remaining months. Discriminant analysis (DA identified Secchi disc depth, dissolved oxygen, permanganate index and total phosphorus as the significant variables for distinguishing variations of different years, with 79.9% correct assignments. Dissolved oxygen, pH and chlorophyll-a were determined to discriminate between the two sampling periods classified by CA, with 87.8% correct assignments. For spatial variation, DA identified Secchi disc depth and ammonia nitrogen as the significant discriminating parameters, with 81.6% correct assignments. Principal component analysis (PCA identified organic pollution, nutrient pollution, domestic sewage, and agricultural and surface runoff as the primary pollution sources, explaining 84.58%, 81.61% and 78.68% of the total variance in Groups A, B and C, respectively. These results demonstrate the effectiveness of integrated use of CA, DA and PCA for reservoir water quality evaluation and could assist managers in improving water resources management.

  7. The application of click chemistry in the synthesis of agents with anticancer activity

    Directory of Open Access Journals (Sweden)

    Ma N

    2015-03-01

    Full Text Available Nan Ma,1–3 Ying Wang,3 Bing-Xin Zhao,3 Wen-Cai Ye,1,3 Sheng Jiang2 1Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, 2Laboratory of Medicinal Chemistry, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, 3Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou, People’s Republic of China Abstract: The copper(I-catalyzed 1,3-dipolar cycloaddition between alkynes and azides (click chemistry to form 1,2,3-triazoles is the most popular reaction due to its reliability, specificity, and biocompatibility. This reaction has the potential to shorten procedures, and render more efficient lead identification and optimization procedures in medicinal chemistry, which is a powerful modular synthetic approach toward the assembly of new molecular entities and has been applied in anticancer drugs discovery increasingly. The present review focuses mainly on the applications of this reaction in the field of synthesis of agents with anticancer activity, which are divided into four groups: topoisomerase II inhibitors, histone deacetylase inhibitors, protein tyrosine kinase inhibitors, and antimicrotubule agents. Keywords: topoisomerase II inhibitors, histone deacetylase inhibitors, protein tyrosine kinase inhibitors, antimicrotubule agents

  8. Passing through the renal clearance barrier: toward ultrasmall sizes with stable ligands for potential clinical applications

    Directory of Open Access Journals (Sweden)

    Zhang XD

    2014-04-01

    Full Text Available Xiao-Dong Zhang,1 Jiang Yang,2 Sha-Sha Song,1 Wei Long,1 Jie Chen,1 Xiu Shen,1 Hao Wang,1 Yuan-Ming Sun,1 Pei-Xun Liu,1 Saijun Fan11Tianjin Key Laboratory of Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, People's Republic of China; 2Department of Biological Systems Engineering, University of Wisconsin-Madison, Madison, WI, USAAbstract: The use of nanoparticles holds promise for medical applications, such as X-ray imaging, photothermal therapy and radiotherapy. However, the in vivo toxicity of inorganic nanoparticles raises some concern regarding undesirable side effects which prevent their further medical application. Ultrasmall sub-5.5 nm particles can pass through the barrier for renal clearance, minimizing their toxicity. In this letter we address some recent interesting work regarding in vivo toxicity and renal clearance, and discuss the possible strategy of utilizing ultrasmall nanomaterials. We propose that small hydrodynamic sized nanoclusters can achieve both nontoxic and therapeutic clinical features.Keywords: in vivo clearance, gold nanoparticles, small size

  9. Practical Stabilization of Uncertain Nonholonomic Mobile Robots Based on Visual Servoing Model with Uncalibrated Camera Parameters

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    Hua Chen

    2013-01-01

    Full Text Available The practical stabilization problem is addressed for a class of uncertain nonholonomic mobile robots with uncalibrated visual parameters. Based on the visual servoing kinematic model, a new switching controller is presented in the presence of parametric uncertainties associated with the camera system. In comparison with existing methods, the new design method is directly used to control the original system without any state or input transformation, which is effective to avoid singularity. Under the proposed control law, it is rigorously proved that all the states of closed-loop system can be stabilized to a prescribed arbitrarily small neighborhood of the zero equilibrium point. Furthermore, this switching control technique can be applied to solve the practical stabilization problem of a kind of mobile robots with uncertain parameters (and angle measurement disturbance which appeared in some literatures such as Morin et al. (1998, Hespanha et al. (1999, Jiang (2000, and Hong et al. (2005. Finally, the simulation results show the effectiveness of the proposed controller design approach.

  10. A configural effect in visual short-term memory for features from different parts of an object.

    Science.gov (United States)

    Delvenne, Jean-François; Bruyer, Raymond

    2006-09-01

    Previous studies have shown that change detection performance is improved when the visual display holds features (e.g., a colour and an orientation) that are grouped into different parts of the same object compared to when they are all spatially separated (Xu, 2002a, 2002b). These findings indicate that visual short-term memory (VSTM) encoding can be "object based". Recently, however, it has been demonstrated that changing the orientation of an item could affect the spatial configuration of the display (Jiang, Chun, & Olson, 2004), which may have an important influence on change detection. The perceptual grouping of features into an object obviously reduces the amount of distinct spatial relations in a display and hence the complexity of the spatial configuration. In the present study, we ask whether the object-based encoding benefit observed in previous studies may reflect the use of configural coding rather than the outcome of a true object-based effect. The results show that when configural cues are removed, the object-based encoding benefit remains for features (i.e., colour and orientation) from different parts of an object, but is significantly reduced. These findings support the view that memory for features from different parts of an object can benefit from object-based encoding, but the use of configural coding significantly helps enlarge this effect.

  11. Book Review: Guide to computer forensics and investigations (3rd ed.

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    Keyu Jiang

    2008-09-01

    Full Text Available Nelson, B., Phillips, A., Enfinger, F., & Steuart, C. (2008. Guide to computer forensics and investigations (3rd ed.. New Jersey: Pearson Education, Inc. 693 pages, ISBN: 1-4180-6733-4 (paper.Reviewed by Keyu Jiang (kjiang@fhsu.edu and Ruifeng Xuan (r_xuan@scatcat.fhsu.edu, Department of Information Networking and Telecommunications, Fort Hays State University, Hays, KS 67601Nelson, Phillips, Enfinger, and Steuart’s book is about the science of computer forensics and its implications in crime investigations. This book is not intended to provide comprehensive training in computer forensics, but introduce the science the science of computer forensics and its implications in crime investigations.  It focused on establishing a solid foundation for those who are new to this field.  Nelson, Philips, Enfiger, and Steuart are experienced experts in different areas of computer forensics.  Different expertise makes this book could benefit many groups of people at different educational level and industrial background.(see PDF for full review

  12. Assessing the aerosol direct and first indirect effects using ACM/GCM simulation results

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    Huang, H.; Gu, Y.; Xue, Y.; Lu, C. H.

    2016-12-01

    Atmospheric aerosols have been found to play an important role in global climate change but there are still large uncertainty in evaluating its role in the climate system. The aerosols generally affect global and regional climate through the scattering and the absorption of solar radiation (direct effect) and through their influences on cloud particle, number and sizes (first indirect effect). The indirect effect will further affects cloud water content, cloud top albedo and surface precipitations. In this study, we investigate the global climatic effect of aerosols using a coupled NCEP Global Forecast System (GFS) and a land surface model (SSiB2) The OPAC (Optical Properties of Aerosols and Clouds) database is used for aerosol effect. The OPAC data provides the optical properties (i.e., the extinction, scattering and absorption coefficient, single-scattering albedo, asymmetry factor and phase function) of ten types of aerosols under various relative humidity conditions for investigating the global direct and first indirect effects of dust aerosols. For indirect forcings due to liquid water, we follow the approach presented by Jiang et al (2011), in which a parameterization of cloud effective radius was calculated to describe its variance with convective strength and aerosol concentration. Since the oceans also play an important role on aerosol climatic effect, we also design a set of simulations using a coupled atmosphere/ocean model (CFS) to evaluate the sensitivity of aerosol effect with two-way atmosphere-ocean interactions.

  13. Successful treatment of paraganglioma with sorafenib: a case report and brief review of the literature

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    Lin Y

    2013-11-01

    Full Text Available Yun Lin,1,* Qun Li,1,* Wei Huang,1 Xinyan Jia,1 Hong Jiang,1 Yong Gao,1 Qi Li1,21Department of Oncology, Shanghai East Hospital, 2Department of Oncology, Shanghai First People's Hospital, Shanghai, People's Republic of China*These authors contributed equally to this work, and are joint first authorsIntroduction: To date, no effective systemic therapies have been made available for paraganglioma. However, multiple mutations in susceptibility genes have been identified that are potential targets for sorafenib, an oral multitargeted tyrosine-kinase inhibitor.Case presentation: We report the case of a 69-year-old Chinese man with mediastinal paraganglioma that had metastasized to the bone. The paraganglioma responded to sorafenib, a novel multi-tyrosine kinase inhibitor that targets angiogenesis, the Raf-kinase pathway, the platelet-derived growth factor Ret, and c-Kit. The patient was diagnosed as having paraganglioma after biopsy of the mediastinal mass. We first treated the patient with radiotherapy. Then he tolerated an etoposide-and-cisplatin chemotherapy regimen. Subsequently, he received 6 months of maintenance treatment with sorafenib (400 mg twice daily. A dramatic reduction in tumor volume was observed. At present, the patient has achieved a partial response, and his clinical status remains unchanged.Conclusion: We suggest that sorafenib should be further investigated in the management of patients with paraganglioma.Keywords: sorafenib, paraganglioma, molecular-targeted drug

  14. Early diagnostic potential of APC hypermethylation in esophageal cancer

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    Wang B

    2018-02-01

    Full Text Available Bujiang Wang,1 Haojun Song,1 Haizhong Jiang,1 Yangbo Fu,1 Xiaoyun Ding,1 Chongchang Zhou2 1Department of Gastroenterology, Laboratory of Digestive Diseases, Ningbo First Hospital, Ningbo, 2Department of Otorhinolaryngology Head and Neck Surgery, Lihuili Hospital of Ningbo University, Ningbo, Zhejiang, People’s Republic of China Background: The hypermethylation of APC gene is observed in various cancers, including esophageal cancer (EC. However, the association between APC methylation and the initiation and progression of EC is poorly understood. Purpose and methods: The current study systematically reviewed studies on abnormal methylation of APC in EC and quantitatively synthesized 18 studies by meta-analysis involving 1008 ECs, 570 Barrett’s esophagus (BE, and 782 controls. Results: Our results showed higher methylation of APC in EC (OR = 23.33, P < 0.001 and BE (OR = 9.34, P < 0.001 than in normal controls. Whereas APC methylation in EC was similar to that in BE (P = 0.052, it was not associated with tumor stage (P = 0.204. Additionally, APC methylation was not significantly associated with overall survival (OS and relapse-free survival (RFS in patients with EC. The performance of APC methylation for the detection of EC and BE achieved areas under the receiver operating characteristic curves of 0.94 and 0.88, respectively. Conclusion: Our results imply that APC methylation detection is a potential diagnostic biomarker for EC and BE. Keywords: esophageal cancer, Barrett’s esophagus, methylation, APC

  15. Modifying tetramethyl–nitrophenyl–imidazoline with amino acids: design, synthesis, and 3D-QSAR for improving inflammatory pain therapy

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    Jiang X

    2015-04-01

    Full Text Available Xueyun Jiang,1 Yuji Wang,1 Haimei Zhu,1 Yaonan Wang,1 Ming Zhao,1,2 Shurui Zhao,1 Jianhui Wu,1 Shan Li,1 Shiqi Peng11Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Engineering Research Center of Endogenous Prophylactic of Ministry of Education of China, Beijing Laboratory of Biomedical Materials, College of Pharmaceutical Sciences, Capital Medical University, Beijing, People’s Republic of China; 2Faculty of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung, TaiwanAbstract: With the help of pharmacophore analysis and docking investigation, 15 novel 1-(4,4,5,5-tetramethyl-2-(3-nitrophenyl-4,5-dihydroimidazol-1-yl-oxyacetyl-L-amino acids (6a–o were designed, synthesized, and assayed. On tail-flick and xylene-induced ear edema models, 10 µmol/kg 6a–o exhibited excellent oral anti-inflammation and analgesic activity. The dose-dependent assay of their representative 6f indicates that the effective dose should be 3.3 µmol/kg. The correlation of the three-dimensional quantitative structure–activity relationship with the docking analysis provides a basis for the rational design of drugs to treat inflammatory pain.Keywords: tetramethylimidazoline, analgesic, anti-inflammatory, 3D-QSAR

  16. PREFACE: MRS International Materials Research Conference (IMRC-2008)

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    Wang, Zhanguo; Qiu, Yong; Li, Yongxiang

    2009-03-01

    This volume contains selected papers presented at the MRS International Materials Research Conference (IMRC-2008) held in Chongqing, China, 9-12 June 2008. IMRC-2008 included 9 symposia of A. Eco/Environmental Materials, B. Sustainable Energy Materials, C. Electronic Packaging Materials, D. Electronic Materials, E. Materials and Processes for Flat-panel Displays, F. Functional Ceramics, G. Transportation Materials, H. Magnesium and I. Biomaterials for Medical Applications. Nearly 1200 participants from 33 countries attended the conference, and the conference organizers received more than 700 papers. After the peer review processes, 555 papers were selected to be published in 9 Journals or proceedings, including J. of Materials Research (JMR), Rare Metal Materials and Engineering, J. of Univ. Science and Technology Beijing, Biomedical Materials: Materials for Tissue Engineering and Regenerative Medicine, Chinese Journal of Aeronautics, Materials Science Forum, and Journal of Physics: Conference Series. Among the 555 selected papers, 91 papers are published in this volume, and the topics mainly cover electronic matrials, processes for flat-panel displays and functional ceramics. The editors would like to give special thanks to the graduate students Liwu Jiang, Ming Li and Di He from Beihang University for their hard work compiling and typesetting each paper in this volume. Zhanguo Wang, Yong Qiu and Yongxiang Li Editors

  17. The Impact of Texting on Comprehension

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    Jamal K. M. Ali

    2015-07-01

    Full Text Available This paper presents a study of the effects of texting on English language comprehension. The authors believe that English used in texting causes a lack of comprehension for English speakers, learners, and texters. Wei, Xian-hai and Jiang (2008:3 declare “In Netspeak, there are some newly-created vocabularies, which people cannot comprehend them either from their partial pronunciation or from their figures.” Crystal (2007:23 claims; “variation causes problems of comprehension and acceptability. If you speak or write differently from the way I do, we may fail to understand each other.”  In this paper, the authors conducted a questionnaire at Aligarh Muslim University to ninety respondents from five different Faculties and four different levels. To measure respondents’ comprehension of English texting, the authors gave the respondents abbreviations used by texters and asked them to write the full forms of the abbreviations. The authors found that many abbreviations were not understood, which suggested that most of the respondents did not understand and did not use these abbreviations.

  18. Geometric Implications of Maxwell's Equations

    Science.gov (United States)

    Smith, Felix T.

    2015-03-01

    Maxwell's synthesis of the varied results of the accumulated knowledge of electricity and magnetism, based largely on the searching insights of Faraday, still provide new issues to explore. A case in point is a well recognized anomaly in the Maxwell equations: The laws of electricity and magnetism require two 3-vector and two scalar equations, but only six dependent variables are available to be their solutions, the 3-vectors E and B. This leaves an apparent redundancy of two degrees of freedom (J. Rosen, AJP 48, 1071 (1980); Jiang, Wu, Povinelli, J. Comp. Phys. 125, 104 (1996)). The observed self-consistency of the eight equations suggests that they contain additional information. This can be sought as a previously unnoticed constraint connecting the space and time variables, r and t. This constraint can be identified. It distorts the otherwise Euclidean 3-space of r with the extremely slight, time dependent curvature k (t) =Rcurv-2 (t) of the 3-space of a hypersphere whose radius has the time dependence dRcurv / dt = +/- c nonrelativistically, or dRcurvLor / dt = +/- ic relativistically. The time dependence is exactly that of the Hubble expansion. Implications of this identification will be explored.

  19. Paraganglioma of the vagina: a case report and review of the literature

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    Cai T

    2014-06-01

    Full Text Available Tao Cai,1 Yucong Li,2 Qingming Jiang,3 Dong Wang,2 Yu Huang2 1Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, 2Department of Gynecologic Oncology, 3Department of Pathology, Chongqing Cancer Research Institute, Chongqing, People’s Republic of China Abstract: Vaginal paraganglioma is a rare and unusual tumor occurring in the vaginal wall. It is a solitary primary paraganglioma, especially in atypical sites. Herein, we report an unusual case of a 17-year-old woman who had not experienced vomiting, or hypertension. She was found to have an immobile solid mass in the right side of her vaginal wall. Positron emission tomography/computed tomography scans revealed a well-defined solid ovoid mass adjacent to the bladder and pelvic floor. Tumor markers were within the normal range. A transient blood pressure increase occurred during the biopsy. After oral administration of antihypertensive drugs, surgery was performed to completely remove the mass. Histopathological examination indicated that it was a paraganglioma of the vagina. Repeat computed tomography examination did not reveal any local recurrence or distant metastasis during the 12-month follow-up period. Keywords: vaginal paraganglioma, neuroendocrine tumor, clinical features, treatment

  20. Covalent heme attachment to the protein in human heme oxygenase-1 with selenocysteine replacing the His25 proximal iron ligand.

    Science.gov (United States)

    Jiang, Yongying; Trnka, Michael J; Medzihradszky, Katalin F; Ouellet, Hugues; Wang, Yongqiang; Ortiz de Montellano, Paul R

    2009-03-01

    To characterize heme oxygenase with a selenocysteine (SeCys) as the proximal iron ligand, we have expressed truncated human heme oxygenase-1 (hHO-1) His25Cys, in which Cys-25 is the only cysteine, in the Escherichia coli cysteine auxotroph strain BL21(DE3)cys. Selenocysteine incorporation into the protein was demonstrated by both intact protein mass measurement and mass spectrometric identification of the selenocysteine-containing tryptic peptide. One selenocysteine was incorporated into approximately 95% of the expressed protein. Formation of an adduct with Ellman's reagent (DTNB) indicated that the selenocysteine in the expressed protein was in the reduced state. The heme-His25SeCys hHO-1 complex could be prepared by either (a) supplementing the overexpression medium with heme, or (b) reconstituting the purified apoprotein with heme. Under reducing conditions in the presence of imidazole, a covalent bond is formed by addition of the selenocysteine residue to one of the heme vinyl groups. No covalent bond is formed when the heme is replaced by mesoheme, in which the vinyls are replaced by ethyl groups. These results, together with our earlier demonstration that external selenolate ligands can transfer an electron to the iron [Y. Jiang, P.R. Ortiz de Montellano, Inorg. Chem. 47 (2008) 3480-3482 ], indicate that a selenyl radical is formed in the hHO-1 His25SeCys mutant that adds to a heme vinyl group.

  1. Tacrolimus in preventing transplant rejection in Chinese patients – optimizing use

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    Li CJ

    2015-01-01

    Full Text Available Chuan-Jiang Li,1,* Liang Li2,* 1Department of Surgery, Nanfang Hospital, 2Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, People’s Republic of China *The authors contributed equally to this work Abstract: Tacrolimus is a product of fermentation of Streptomyces, and belongs to the family of calcineurin inhibitors. It is a widely used immunosuppressive drug for preventing solid-organ transplant rejection. Compared to cyclosporine, tacrolimus has greater immunosuppressive potency and a lower incidence of side effects. It has been accepted as first-line treatment after liver and kidney transplantation. Tacrolimus has specific features in Chinese transplant patients; its in vivo pharmacokinetics, treatment regimen, dose and administration, and adverse-effect profile are influenced by multiple factors, such as genetics and the spectrum of primary diseases in the Chinese population. We reviewed the clinical experience of tacrolimus use in Chinese liver- and kidney-transplant patients, including the pharmacology of tacrolimus, the immunosuppressive effects of tacrolimus versus cyclosporine, effects of different factors on tacrolimus metabolism on Chinese patients, personalized medicine, clinical safety profile, and patient satisfaction and adherence. This article provides guidance for the rational and efficient use of tacrolimus in Chinese organ-transplant patients. Keywords: tacrolimus, liver transplantation, kidney transplant, Chinese, personalized medicine

  2. A case of 18p deletion syndrome after blepharoplasty

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    Xu LJ

    2017-01-01

    Full Text Available Li-juan Xu,1 Lv-xian Wu,2 Qing Yuan,3 Zhi-gang Lv,1 Xue-yan Jiang2 1Department of Opthalmology, 2Department of Pediatrics, 3Department of Clinical Laboratory, Jinhua Central Hospital, Jinhua, Zhejiang, People’s Republic of China Objective: The deletion of the short arm of chromosome 18 is thought to be one of the rare chromosomal aberrations. Here, we report a case to review this disease.Case report: The proband is a five-and-a-half-year-old girl who has had phenotypes manifested mainly by ptosis, broad face, broad neck with low posterior hairline, mental retardation, short stature, and other malformations. Chromosomal analysis for her mother showed a normal karyotype. Her father and younger brother were phenotypically normal.Result: Phenotypical features were quite similar throughout other cases and in accordance with the usual phenotype of del(18p suggested within the same cases and among the del(18p cases described. She underwent blepharoplasty, which improved her appearance.Conclusion: 18p deletion syndrome is diagnosed by gene analysis. Plastic surgeries for improving the appearance might be an option for these patients. Keywords: chromosome, deletion, blepharoplasty

  3. Spatial Heterogeneity, Scale, Data Character and Sustainable Transport in the Big Data Era

    Science.gov (United States)

    Jiang, Bin

    2018-04-01

    In light of the emergence of big data, I have advocated and argued for a paradigm shift from Tobler's law to scaling law, from Euclidean geometry to fractal geometry, from Gaussian statistics to Paretian statistics, and - more importantly - from Descartes' mechanistic thinking to Alexander's organic thinking. Fractal geometry falls under the third definition of fractal - that is, a set or pattern is fractal if the scaling of far more small things than large ones recurs multiple times (Jiang and Yin 2014) - rather than under the second definition of fractal, which requires a power law between scales and details (Mandelbrot 1982). The new fractal geometry is more towards living geometry that "follows the rules, constraints, and contingent conditions that are, inevitably, encountered in the real world" (Alexander et al. 2012, p. 395), not only for understanding complexity, but also for creating complex or living structure (Alexander 2002-2005). This editorial attempts to clarify why the paradigm shift is essential and to elaborate on several concepts, including spatial heterogeneity (scaling law), scale (or the fourth meaning of scale), data character (in contrast to data quality), and sustainable transport in the big data era.

  4. Differential Visual Processing of Animal Images, with and without Conscious Awareness.

    Science.gov (United States)

    Zhu, Weina; Drewes, Jan; Peatfield, Nicholas A; Melcher, David

    2016-01-01

    The human visual system can quickly and efficiently extract categorical information from a complex natural scene. The rapid detection of animals in a scene is one compelling example of this phenomenon, and it suggests the automatic processing of at least some types of categories with little or no attentional requirements (Li et al., 2002, 2005). The aim of this study is to investigate whether the remarkable capability to categorize complex natural scenes exist in the absence of awareness, based on recent reports that "invisible" stimuli, which do not reach conscious awareness, can still be processed by the human visual system (Pasley et al., 2004; Williams et al., 2004; Fang and He, 2005; Jiang et al., 2006, 2007; Kaunitz et al., 2011a). In two experiments, we recorded event-related potentials (ERPs) in response to animal and non-animal/vehicle stimuli in both aware and unaware conditions in a continuous flash suppression (CFS) paradigm. Our results indicate that even in the "unseen" condition, the brain responds differently to animal and non-animal/vehicle images, consistent with rapid activation of animal-selective feature detectors prior to, or outside of, suppression by the CFS mask.

  5. REVIEW: A GRAMMAR OF GUÌQIÓNG

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    Jesse P. Gates

    2018-05-01

    Full Text Available Jiāng Lì. 2015. A Grammar of Guìqióng: A Language of Sichuan. Leiden: Brill. xiv + 452 pp. ISBN 9789004292093 (hardback 213USD - E-ISBN 9789004293045 (electronic 217USD. Jiang Li's A Grammar of Guìqióng (henceforth, AGG is a revision of her PhD dissertation at the University of Berne under the supervision of George Van Driem. It is a most welcome contribution to our understanding of this under-described language. The primary dialects of Guiqiong described in AGG are spoken in Changma Village of Maibeng Township and Qianxi Village of Qianxi Township, both in Kangding County, Ganzi Tibetan Autonomous Prefecture, Sichuan Province, China. Some praiseworthy aspects of AGG include a plethora of examples sentences; a total of about 1500 example sentences are in the book. Included in the list of abbreviations are the linguistic forms from Guiqiong. The inclusion of photographs of the Guiqiong people and their geographic setting adds interest and appeal to the book. Appendix 1 (321-347 contains six texts of "sayings, stories, and recollections." This review is divided into sections similar to the divisions that the chapters of AGG provide: Introduction to AGG, Phonology, Morphology, Syntax, Errata, and Conclusion. Comments on AGG's chapter on pragmatics will be incorporated into the section on syntax since AGG's chapter on pragmatics is very short. Back-matter will also be briefly overviewed in the syntax section. ...

  6. Formality of the Chinese collective leadership.

    Science.gov (United States)

    Li, Haiying; Graesser, Arthur C

    2016-09-01

    We investigated the linguistic patterns in the discourse of four generations of the collective leadership of the Communist Party of China (CPC) from 1921 to 2012. The texts of Mao Zedong, Deng Xiaoping, Jiang Zemin, and Hu Jintao were analyzed using computational linguistic techniques (a Chinese formality score) to explore the persuasive linguistic features of the leaders in the contexts of power phase, the nation's education level, power duration, and age. The study was guided by the elaboration likelihood model of persuasion, which includes a central route (represented by formal discourse) versus a peripheral route (represented by informal discourse) to persuasion. The results revealed that these leaders adopted the formal, central route more when they were in power than before they came into power. The nation's education level was a significant factor in the leaders' adoption of the persuasion strategy. The leaders' formality also decreased with their increasing age and in-power times. However, the predictability of these factors for formality had subtle differences among the different types of leaders. These results enhance our understanding of the Chinese collective leadership and the role of formality in politically persuasive messages.

  7. Convergence of genetic and environmental factors on parvalbumin-positive interneurons in schizophrenia

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    Zhihong eJiang

    2013-09-01

    Full Text Available Schizophrenia etiology is thought to involve an interaction between genetic and environmental factors during postnatal brain development. However, there is a fundamental gap in our understanding of the molecular mechanisms by which environmental factors interact with genetic susceptibility to trigger symptom onset and disease progression. In this review, we summarize the most recent findings implicating oxidative stress as one mechanism by which environmental insults, especially early life social stress, impact the development of schizophrenia. Based on a review of the literature and the results of our own animal model, we suggest that environmental stressors such as social isolation render parvalbumin-positive interneurons vulnerable to oxidative stress. We previously reported that social isolation stress exacerbates many of the schizophrenia-like phenotypes seen in a conditional genetic mouse model of schizophrenia in which NMDARs are selectively ablated in half of cortical and hippocampal interneurons during early postnatal development (Belforte et al., 2010. We have since revealed that this social isolation-induced effect is caused by impairments in the antioxidant defense capacity in the parvalbumin-positive interneurons in which NMDARs are ablated. We propose that this effect is mediated by the down-regulation of PGC-1α, a master regulator of mitochondrial energy metabolism and anti-oxidant defense, following the deletion of NMDARs (Jiang et al, 2013. Other potential molecular mechanisms underlying redox dysfunction upon gene and environmental interaction will be discussed, with a focus on the unique properties of parvalbumin-positive interneurons.

  8. Effects of packet retransmission with finite packet lifetime on traffic capacity in scale-free networks

    Science.gov (United States)

    Jiang, Zhong-Yuan; Ma, Jian-Feng

    Existing routing strategies such as the global dynamic routing [X. Ling, M. B. Hu, R. Jiang and Q. S. Wu, Phys. Rev. E 81, 016113 (2010)] can achieve very high traffic capacity at the cost of extremely long packet traveling delay. In many real complex networks, especially for real-time applications such as the instant communication software, extremely long packet traveling time is unacceptable. In this work, we propose to assign a finite Time-to-Live (TTL) parameter for each packet. To guarantee every packet to arrive at its destination within its TTL, we assume that a packet is retransmitted by its source once its TTL expires. We employ source routing mechanisms in the traffic model to avoid the routing-flaps induced by the global dynamic routing. We compose extensive simulations to verify our proposed mechanisms. With small TTL, the effects of packet retransmission on network traffic capacity are obvious, and the phase transition from flow free state to congested state occurs. For the purpose of reducing the computation frequency of the routing table, we employ a computing cycle Tc within which the routing table is recomputed once. The simulation results show that the traffic capacity decreases with increasing Tc. Our work provides a good insight into the understanding of effects of packet retransmission with finite packet lifetime on traffic capacity in scale-free networks.

  9. Advances in the targeted therapy of liposarcoma

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    Guan Z

    2015-01-01

    Full Text Available Zhonghai Guan,1 Xiongfei Yu,1 Haohao Wang,1 Haiyong Wang,1 Jing Zhang,1 Guangliang Li,2 Jiang Cao,3 Lisong Teng1 1Department of Surgical Oncology, First Affiliated Hospital, College of Medicine, Zhejiang University, 2Department of Medicine Oncology, Zhejiang Cancer Hospital, 3Clinical Research Center, The 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People’s Republic of China Abstract: Liposarcoma (LPS is the most common type of soft-tissue sarcoma. Complete surgical resection is the only curative means for localized disease; however, both radiation and conventional cytotoxic chemotherapy remain controversial for metastatic or unresectable disease. An increasing number of trials with novel targeted therapy of LPS have provided encouraging data during recent years. This review will provide an overview of the advances in our understanding of LPS and summarize the results of recent trials with novel therapies targeting different genetic and molecular aberrations for different subtypes of LPS. Keywords: well-/dedifferentiated, myxoid/round cell, pleomorphic, soft-tissue sarcoma

  10. Efficient lifetime estimation techniques for general multiaxial loading

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    Papuga, Jan; Halama, Radim; Fusek, Martin; Rojíček, Jaroslav; Fojtík, František; Horák, David; Pecha, Marek; Tomčala, Jiří; Čermák, Martin; Hapla, Václav; Sojka, Radim; Kružík, Jakub

    2017-07-01

    In this paper, we discuss and present our progress toward a project, which is focused on fatigue life prediction under multiaxial loading in the domain of low-cycle fatigue, i.e. cases, where the plasticity cannot be neglected. First, the elastic-plastic solution in the finite element analysis is enhanced and verified on own experiments. Second, the method by Jiang describing the instantaneous damage increase by analyses of load time by time, is in implementation phase. In addition, simplified routines for conversion of elastic stresses-strains to elastic-plastic ones as proposed by Firat and Ye et.al. are evaluated on the basis of data gathered from external sources. In order to produce high quality complex analyses, which could be feasible in an acceptable time, and allow the period for next analyses of results to be expanded; the core of PragTic fatigue solver used for all fatigue computations are being re-implemented to get the fully parallelized scalable solution.

  11. Growth Comparison of Israeli Carp (Cyprinus carpio) to Different Breeding Combination

    Science.gov (United States)

    Hwang, Ju-ae; Goo, In Bon; Kim, Jung Eun; Kim, Myung Hun; Kim, Do Hee; Im, Jae Hyun; Choi, Hye-Sung; Lee, Jeong-Ho

    2016-01-01

    ABSTRACT The purpose of this study was to investigate the improvement of growth in Israeli carp (Cyprinus carpio), and the cross experiment was carried out with two strains of Israeli carp. Four combinations of Israeli carp from Jeonbuk fisheries farm and Songpu mirror carp from Heilong Jiang, China (KK; Jeonbuk ♀ × Jeonbuk ♂, KC; Jeonbuk ♀ × China ♂, CC; China ♀ × China ♂ and CK; China ♀ × Jeonbuk ♂) were developed and reared. Body length, body weight and condition factor were determined at 20, 40, 60 and 170 days post-hatch (DPH). The results showed that there were differences in growth rate of the four groups. Body length of four groups were CK > CC > KC > KK and body weight were CC > CK > KC > KK at 170 DPH. The growth perfomance of four groups were statistically significant difference (P<0.05). During the rearing, CC group had longer length and higher weight at 170 DPH compared to other three groups and also condition factor was highest in the CC group, but there was no significant difference in a survival rate. These results indicated that the growth performance mainly depended upon brooder combination but survival rate could not significantly affect brooder. PMID:28144632

  12. Corrupção e Crescimento: os impactos da corrupção ponderados pelos diferentes graus de eficiência entre as firmas

    Directory of Open Access Journals (Sweden)

    Leonardo Andrade Rocha

    Full Text Available Resumo O presente estudo analisou os impactos da corrupção no crescimento das firmas conforme diferentes 'graus' de eficiência. Usando uma técnica não paramétrica de escores de eficiência, foi estimado um modelo de regressão linear interagindo os diferentes escores com um índice de corrupção. Os resultados apontam que a corrupção apresenta impactos negativos nas firmas com baixa performance, ao contrário das firmas com alta performance. Neste sentido, a posição da firma eficiente conforme a fronteira quantílica condiciona significativamente o custo da corrupção, sugerindo um efeito heterogêneo que não é precisamente capturado pelas técnicas tradicionais. Tais resultados corroboram com importantes estudos destacando Batra, Kaufmann e Stone (2003, Wang e You (2012 e Jiang e Nie (2014.

  13. Aberrant overexpression of vascular endothelial growth factor in pancreatic ductal adenocarcinoma is associated with aggressive clinical behavior

    Directory of Open Access Journals (Sweden)

    Naomi Y Jiang

    2010-07-01

    Full Text Available Naomi Y Jiang1, Bruce A Woda2, Liping Zhang2, Suyang Hao2, Karen A Dresser2, Di Lu21Massachusetts Institute of Technology, Worcester, MA, USA; 2Department of Pathology, University of Massachusetts Medical Center, Worcester, MA, USAAbstract: Pancreatic adenocarcinoma is a leading cause of cancer-related deaths in the United States. In this study, we studied vascular endothelial growth factor (VEGF expression in ­pancreatic adenocarcinoma by immunohistochemical staining. Clinical follow-up and survival data were analyzed. We determined that VEGF was aberrantly overexpressed in a subset of primary pancreatic adenocarcinoma. Statistically, VEGF overexpression was associated with higher stage, higher grade, and lymph node metastasis (P < 0.001, P = 0.012, and P < 0.005, respectively. Additionally, patients of this subset had a much shorter overall survival than patients without VEGF overexpression, as evidenced by Kaplan–Meier plots and the log-rank test (P = 0.001. The 5-year overall survival rate was 17% in patients with VEGF overexpression compared to 52% in patients without VEGF overexpression. The median survival was only 13 months for patients with VEGF overexpression compared to 65 months for patients without. In conclusion, VEGF is a biomarker that identifies a subset of pancreatic ductal adenocarcinoma with aggressive clinical behavior.Keywords: pancreatic adenocarcinoma, VEGF, cancer

  14. Femtosecond index change mechanisms and morphology of SiC crystalline materials

    International Nuclear Information System (INIS)

    DesAutels, Logan; Brewer, Christopher; Powers, Peter; Walker, Mark; Tomlin, David; Fratini, Albert; Juhl, Shane; Chen Weibin

    2009-01-01

    Femtosecond lasers have a unique ability of processing bulk transparent materials for various applications such as micromachining, waveguide manufacturing, and photonic bandgap structures just to name a few. These applications depend on the formation of micron or submicron size features that are known to be index modifications to the bulk substrate [H. Guo, H. Jiang, Y. Fang, C. Peng, H. Yang, Y. Li, Q. Gong, J. Opt. A: Pure Appl. Opt. 6 (2004) 787]. To the best of our knowledge the physical understanding of how these index-modified features are formed is still unknown, but many good theories exist such as Petite et al. [G. Petite, P. Daguzan, S. Guizard, P. Martin, in: IEEE Annual Report Conference on Electrical Insulation and Dielectric Phenomena, vol. 15, IEEE, 1995, pp. 40-44] or Tien et al. [A. Tien, S. Backus, H. Kapteyn, M. Murnane, G. Mourou, Phys. Rev. Lett. 82 (1999) 3883]. In this Letter the question on the physical cause for index changes is investigated by the combined efforts between Wright-Patterson AFB (WPAFB) and the University of Dayton (UD) using numerous imaging equipment such as TEM, AFM, NSOM, Nomarski microscopy, X-ray crystallography, Raman spectroscopy, and even diffraction efficiency experiments. With all the combined imaging equipment this research is able to present valuable data and deduce plausible theories of the physics of the index modification mechanism

  15. Novel free paclitaxel-loaded poly(L-γ-glutamylglutamine–paclitaxel nanoparticles

    Directory of Open Access Journals (Sweden)

    Danbo Yang

    2011-01-01

    Full Text Available Danbo Yang1, Sang Van2, Xinguo Jiang3, Lei Yu1,21Biomedical Engineering and Technology Institute, Institutes for Advanced Interdisciplinary Research, East China Normal University, Shanghai, People's Republic of China; 2Biomedical Group, Nitto Denko Technical Corporation, Oceanside, CA, USA; 3School of Pharmacy, Fudan University, Shanghai, People's Republic of ChinaAbstract: The purpose of this study was to develop a novel formulation of paclitaxel (PTX that would improve its therapeutic index. Here, we combined a concept of polymer–PTX drug conjugate with a concept of polymeric micelle drug delivery to form novel free PTX-loaded poly(L-γ-glutamylglutamine (PGG–PTX conjugate nanoparticles. The significance of this drug formulation emphasizes the simplicity, novelty, and flexibility of the method of forming nanoparticles that contain free PTX and conjugated PTX in the same drug delivery system. The results of effectively inhibiting tumor growth in mouse models demonstrated the feasibility of the nanoparticle formulation. The versatility and potential of this dual PTX drug delivery system can be explored with different drugs for different indications. Novel and simple formulations of PTX-loaded PGG–PTX nanoparticles could have important implications in translational medicines.Keywords: paclitaxel, polymeric micelle, poly(L-γ-glutamylglutamine–paclitaxel, nanoconjugate, nanoparticles

  16. Comparison of response formats and concurrent hedonic measures for optimal use of the EmoSensory® Wheel.

    Science.gov (United States)

    Schouteten, Joachim J; Gellynck, Xavier; De Bourdeaudhuij, Ilse; Sas, Benedikt; Bredie, Wender L P; Perez-Cueto, Federico J A; De Steur, Hans

    2017-03-01

    The study of emotional and sensory profiling with food products is gaining momentum in the field of sensory research. These methods can be applied in order to obtain a broader consumer perspective on product performance beyond traditional hedonic measurements (Jiang, King, & Prinyawiwatkul, 2014; Varela & Ares, 2012). The EmoSensory® Wheel, a recently introduced method which combines emotional and sensory assessment in a wheel questionnaire format is one example of conducting such a task in a consumer-friendly way. However, little is known about its performance compared to a traditional list-based questionnaire format. This comparison is undertaken in this study for two product categories (chocolate and yogurt). Further, two methodological issues are addressed by (i) comparing the use of Check-All-That-Apply (CATA) and rate-all-that-apply (RATA) response formats and (ii) examining whether the method impacts on the concurrent hedonic product assessment for two product categories (chocolate and yogurt). Although both questionnaire formats showed similar findings, more consumers preferred the wheel questionnaire format. Regarding the latter, CATA and RATA scaling yielded similar performance and no influence on the concurrent hedonic assessment was found. This study lends further support for combining emotional and sensory measurements using the EmoSensory® profile, which is of interest for food scientists and the food industry. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Analysis and improvement of the quantum image matching

    Science.gov (United States)

    Dang, Yijie; Jiang, Nan; Hu, Hao; Zhang, Wenyin

    2017-11-01

    We investigate the quantum image matching algorithm proposed by Jiang et al. (Quantum Inf Process 15(9):3543-3572, 2016). Although the complexity of this algorithm is much better than the classical exhaustive algorithm, there may be an error in it: After matching the area between two images, only the pixel at the upper left corner of the matched area played part in following steps. That is to say, the paper only matched one pixel, instead of an area. If more than one pixels in the big image are the same as the one at the upper left corner of the small image, the algorithm will randomly measure one of them, which causes the error. In this paper, an improved version is presented which takes full advantage of the whole matched area to locate a small image in a big image. The theoretical analysis indicates that the network complexity is higher than the previous algorithm, but it is still far lower than the classical algorithm. Hence, this algorithm is still efficient.

  18. Hürthle cell carcinoma: current perspectives

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    Ahmadi S

    2016-11-01

    Full Text Available Sara Ahmadi,1 Michael Stang,2 Xiaoyin “Sara” Jiang,3 Julie Ann Sosa2,4,5 1Division of Endocrinology, Department of Medicine, 2Section of Endocrine Surgery, Department of Surgery, 3Department of Pathology, Duke University Medical Center, 4Duke Cancer Institute, 5Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA Abstract: Hürthle cell carcinoma (HCC can present either as a minimally invasive or as a widely invasive tumor. HCC generally has a more aggressive clinical behavior compared with the other differentiated thyroid cancers, and it is associated with a higher rate of distant metastases. Minimally invasive HCC demonstrates much less aggressive behavior; lesions <4 cm can be treated with thyroid lobectomy alone, and without radioactive iodine (RAI. HCC has been observed to be less iodine-avid compared with other differentiated thyroid cancers; however, recent data have demonstrated improved survival with RAI use in patients with HCC >2 cm and those with nodal and distant metastases. Patients with localized iodine-resistant disease who are not candidates for a wait-and-watch approach can be treated with localized therapies. Systemic therapy is reserved for patients with progressive, widely metastatic HCC. Keywords: thyroid cancer, thyroid nodule, follicular cell carcinoma, Hurthle cell lesion, minimally invasive HCC

  19. Effectiveness and Appropriateness of mHealth Interventions for Maternal and Child Health: Systematic Review.

    Science.gov (United States)

    Chen, Huan; Chai, Yanling; Dong, Le; Niu, Wenyi; Zhang, Puhong

    2018-01-09

    The application of mobile health (mHealth) technology in reproductive, maternal, newborn, and child health (RMNCH) is increasing worldwide. However, best practice and the most effective mHealth interventions have not been reviewed systematically. A systematic review and meta-analysis of studies of mHealth interventions for RMNCH around the world were conducted to investigate their characteristics as well as the features and effectiveness of mHealth interventions. Studies of mHealth interventions for RMNCH between January 2011 and December 2016 were retrieved from 6 databases (PubMed, EMBASE, Global Health, China National Knowledge Infrastructure, VIP Database for Chinese Technical Periodicals, and Wanfang Data Knowledge Service Medium). Comparable studies were included in a random-effects meta-analysis for both exclusive breastfeeding (EBF) and antenatal checks (ANC). Descriptive analyses were conducted for mHealth studies with a range of study designs. Analyses of 245 studies were included, including 51 randomized controlled trials (RCTs). Results showed that there are increasing numbers of studies on mHealth interventions for RMNCH. Although 2 meta-analysis, one with 2 RCTs on EBF (odds ratio [OR] 2.03, 95% CI 1.34-3.08, I 2 =25%) and the other with 3 RCTs on ANC (OR 1.43, 95% CI 1.13-1.79, I 2 =78%), showed that mHealth interventions are more effective than usual care, almost half (43%) of RCTs showed negative or unclear results on mHealth interventions. Functions described in mHealth interventions were diverse, and the health stages covered were broad. However, single function or single stage appeared to be dominant among mHealth interventions compared with multiple functions or stages. More rigorous evaluations are needed to draw consistent conclusions and to analyze mHealth products with multiple functions, especially those popular in the app markets. ©Huan Chen, Yanling Chai, Le Dong, Wenyi Niu, Puhong Zhang. Originally published in JMIR Mhealth and Uhealth

  20. Are psychiatric comorbidities and associated cognitive functions related to treatment response to methylphenidate in boys with attention-deficit/hyperactivity disorder?

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    Chan MH

    2017-04-01

    Full Text Available Mandy H Chan,1 Patrick WL Leung,2 Ting-pong Ho,3 Se-fong Hung,4 Chi-chiu Lee,5 Chun-pan Tang,5 Ka-chai Cheung,2 Fung-yee Ching,2 Fefe HK Chan,6 Lu-hua Chen,2 Merce Garcia-Barcelo,7 Pak-chung Sham3 1Department of Clinical Psychology, Kowloon Hospital, Hospital Authority, 2Department of Psychology, The Chinese University of Hong Kong, 3Department of Psychiatry, University of Hong Kong, 4Department of Psychiatry, The Chinese University of Hong Kong, 5Department of Psychiatry, Kwai Chung Hospital, Hospital Authority, 6Department of Clinical Psychology, Alice Ho Mui Ling Nethersole Hospital, Hospital Authority, 7Department of Surgery, University of Hong Kong, Hong Kong, People’s Republic of China Background: Methylphenidate (MPH has been found to be an effective medication for attention-deficit/hyperactivity disorder (ADHD. However, there are neither consistent nor sufficient findings on whether psychiatric comorbidities and associated cognitive functions of ADHD are related to treatment response to MPH in ADHD children.Objectives: This study investigated whether psychiatric comorbidities, IQ, and neurocognitive deficits are related to treatment response to MPH in ADHD children. In some ways, it is preferable to have a drug that the effectiveness of which to a disorder is not affected by its associated cognitive functions and psychiatric comorbidities. On the other hand, it is likely that the baseline symptom severity of ADHD is associated with the effectiveness of MPH treatment on the symptoms post treatment.Methods: A total of 149 Chinese boys (aged 6–12 years with ADHD, combined type, and normal IQ participated in this study. Assessment of ADHD symptom severity was conducted pre and post MPH treatment, while assessment of psychiatric comorbidities, IQ, and neurocognitive deficits was performed in a non-medicated condition. Treatment response was defined as the ADHD symptom severity post MPH treatment.Results: Results indicated that MPH

  1. Abiding by the sufficiency economy philosophy to develop the quality of life of teachers and educational personnel in the central region

    Science.gov (United States)

    Khumkhong, Tippawan

    2018-01-01

    This research aimed to 1) study the ideas and procedures of the Sufficiency Economy Philosophy (SEP) to make it fully implemented to develop the quality of life of teachers and educational personnel in the central region, 2) study the results of implementing the SEP and 3) offer some guidelines in implementing the SEP to develop the quality of life. The samples were the teachers and educational personnel, the cremation service welfare members of 2015 in 9 provinces of the central region namely Bangkok, Sing Buri, Saraburi, Chai Nat, Nonthaburi, Pathum Thani, Pha Nakhon Si Ayuttaya, Lop Buri and Ang Thong. The qualitative research's samples were the 6 key informants selected purposely, collected by depth-interview, analyzed using inductive method, checked by the methodological triangulation and the key informants. The quantitative research's samples were the 398 offered obtained by stratified random sampling having regard to the ratio, collected by questionnaire with the reliability value of 0.982, analyzed by percentage, mean and standard deviation. The findings were as follows: 1) As for the ideas towards the SEP and the ethical principles of Buddhism are one and the same thing. All levels of people can follow this philosophy. The procedures towards the SEP to develop the quality of life by performing in harmony with their daily lives regarding to the moderation, the reasonableness, building self-immunity with knowledge and ethical qualification. 2) The SEP helps develop the better quality of life, happiness, sound life, sound economy with great satisfaction of the living. 3) On offering some guidelines in implementing the SEP to develop the quality of life: 3.1) the performers must have good understanding in the philosophy and accept to bring it into use 3.2) lead a life according to the ethical principles of Buddhism or to the ones of the religion you believe. 3.3) members of the family had to cooperate in leading lives according to the SEP and 3.4) save money

  2. Current perspectives on bisphosphonate treatment in Paget’s disease of bone

    Directory of Open Access Journals (Sweden)

    Wat WZM

    2014-11-01

    Full Text Available Winnie Zee Man Wat Department of Medicine, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong Abstract: Paget’s disease of bone is a chronic metabolic bone disease with focal increase in bone turnover. The exact etiology of the disease is uncertain, although genetic and environmental factors are believed to be important. Bisphosphonate is the main class of medication being used to control disease activity via its antiresorptive effect. This review discusses the controversies concerning the use of bisphosphonates in the treatment of Paget’s disease of bone, the efficacy of different bisphosphonates in controlling disease activity, and the possible rare side effects of bisphosphonates. Symptoms are the main indication for treatment in Paget’s disease of bone. As treatment benefits in asymptomatic individuals remain controversial and nonevidence based, the decision to treat these patients should be individualized to their risk and benefit profiles. There are several trials conducted to evaluate and compare the efficacy of different regimes of bisphosphonates for treating Paget’s disease of bone. Most trials used biochemical markers rather than clinical symptoms or outcomes as parameters for comparison. Zoledronate is an attractive option as it can achieve high rates of biochemical remission and sustain long duration of suppression by a single dose. Atypical femoral fracture and osteonecrosis of the jaw are two rare and severe side effects reported, possibly related to the use of bisphosphonates in patients with osteoporosis and malignancy-induced hypercalcemia. As the regimes of bisphosphonates used for treating Paget’s disease of bone are different from those two diseases, the risks of developing these two possible side effects are expected to be very low, although this remains unknown. Vitamin D and calcium supplement should be given to patients at risk of vitamin D insufficiency when given zoledronate, as symptomatic

  3. Social support received by multidrug-resistant tuberculosis patients and related factors: a cross-sectional study in Zhejiang Province, People's Republic of China

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    Chen B

    2016-06-01

    Full Text Available Bin Chen,1 Yin Peng,1 Lin Zhou,1 Chengliang Chai,1 Hui-Chi Yeh,2 Songhua Chen,1 Fei Wang,1 Mingwu Zhang,1 Tieniu He,1 Xiaomeng Wang1 1Department of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Binjiang District, Hangzhou, People’s Republic of China; 2Politics & International Relations, Social Sciences, University of Southampton, Southampton, UK Objectives: The objective of this study is to assess the social support received by patients diagnosed with multidrug-resistant tuberculosis (MDR-TB in Zhejiang Province, People’s Republic of China and the factors that may have influenced it. Methods: A total of 220 MDR-TB patients participated in the questionnaire-based survey, and the data from 212 valid questionnaires were analyzed. The respondents reported their sociodemographic status, disease features, and attitudes toward the disease. The social support rating scale was used to measure the patients’ social support scores. An Independent Samples t-test, one-way analysis of variance, and a multiple linear regression model were used to analyze the related factors for the social support scores. Result: The average social support score of each MDR-TB patient was 32.56±7.86. Participants who were single, widowed or divorced, retired, and had fewer family members and lower family income were found to have lower social support scores. Participants unwilling to disclose their disease tended to have less social support (31.59<34.23, P=0.010. Participants who perceived great help from health care workers reported higher social support rating scale scores than those who perceived no help (35.36>29.89, P=0.014. Conclusion: MDR-TB patients in Zhejiang Province were shown to have a low level of social support. Patients who were not married, had smaller families, and lower family income received less social support, suggesting that family harmony could be an important source of social support. Patients

  4. Study of Scientific Problem-Solving Abilities Based on Scientific Knowledge about Atmosphere and Weather for Seventh Grade Students

    Directory of Open Access Journals (Sweden)

    Phoorin Thaengnoi

    2017-06-01

    Full Text Available The purposes of this research were: 1 to develop scientific problem-solving abilities test based on scientific knowledge about atmosphere and weather for seventh grade students and 2 to study the scientific problem-solving abilities of seventh grade students. The samples used in this study were 47 students who were studying in seventh grade in academic year 2015 of a school in Chai Nat province, Thailand. Purposive sampling was applied for identifying the samples. The research instrument of this study was the scientific problem-solving abilities test developed by the researcher. The research data was analyzed by comparing students’ scores with the criteria and considering students’ answers in each element of scientific problem-solving abilities. The results of the study were as follows: The scientific problem-solving abilities test composed of 2 parts. The first part was multiple-choice questions which was composed of 4 situations, a total of 20 questions. The Index of Item Objective Congruence of this part was varied in the range between 0.67 – 1.00. The difficulty and the discrimination level were in the range between 0.33 – 0.63 and 0.27 – 0.67, respectively. The reliability levels of this part was equal to 0.81. The second part of the test was subjective questions which composed of 2 situations, a total of 10 questions. The Index of Item Objective Congruence of this part was varied in the range between 0.67 – 1.00. The reliability level of this part was equal to 0.83. Besides, all questions in the test were covered all elements of scientific problem-solving abilities ; 1 identifying the problem 2 making the hypothesis 3 collecting data and knowledge to solve the problem 4 identifying problem-solving method and 5 predicting the characteristics of the results. The problem-solving abilities of the students revealed that 40.43% of students (n=19 were in a moderate level and 59.57% of students (n=28 were in a low level with the

  5. Indoor air quality investigation at air-conditioned and non-air-conditioned markets in Hong Kong

    International Nuclear Information System (INIS)

    Guo, H.; Lee, S.C.; Chan, L.Y.

    2004-01-01

    To characterize indoor air quality at the markets in Hong Kong, three non-air-conditioned and two air-conditioned markets were selected for this study. The indoor air pollutants measured included PM 10 (particulate matters with aerodynamic diameter less than 10 μm), total bacteria count (TBC), carbon monoxide (CO), nitric oxide (NO), nitrogen dioxide (NO 2 ) and sulfur dioxide (SO 2 ). The indoor and outdoor concentrations of these target air pollutants at these markets were measured and compared. The effects of air conditioning, temperature/relative humidity variation and different stalls on the indoor air quality were also investigated. The results indicated that all of the average indoor concentrations of PM 10 , TBC, CO and NO 2 at the markets were below the Hong Kong Indoor Air Quality Objectives (HKIAQO) standards with a few exceptions for PM 10 and TBC. The elevated PM 10 concentrations at Hung Hom, Ngau Tau Kok and Wan Chai markets were probably due to the air filtration of outdoor airborne particulates emitted from vehicular exhaust, whereas high concentrations of airborne bacteria at Sai Ying Pun and Tin Shing markets were linked to the use of air conditioning. Correlation analysis demonstrated that indoor bacteria concentrations were correlated with temperature and relative humidity. The operation of air conditioning did not significantly reduce the levels of air pollutants at the markets. However, the higher indoor/outdoor ratios demonstrated that the operation of air conditioning had influence on the levels of bacteria at the markets. It was found that average PM 10 concentration at poultry stalls was higher than the HKIAQO standard of 180 μg/m 3 , and was over two times that measured at vegetable, fish and meat stalls. Furthermore, the concentration of airborne bacteria at the poultry stalls was as high as 1031 CFU/m 3 , which was above the HKIAQO standard of 1000 CFU/m 3 . The bacteria levels at other three stalls were all below the HKIAQO standard

  6. Investigation of the Phenomenon of Propagated Sensation along the Channels in the Upper Limb Following Administration of Acupuncture and Mock Laser.

    Science.gov (United States)

    Razavy, Shohreh; Gadau, Marcus; Zhang, Shi Ping; Wang, Fu Chun; Bangrazi, Sergio; Berle, Christine; Harahap, Mahrita; Li, Tie; Li, Wei Hong; Zaslawski, Christopher

    2017-10-01

    Similar to De Qi psychophysical responses, propagated sensation along the channels (PSC) is considered an important phenomenon in traditional Chinese acupuncture. In acupuncture clinical trials, different acupuncture manipulation techniques are used to enhance the propagation of sensation along the channels to facilitate an optimum therapeutic result. To examine and compare the PSC reported by participants in a clinical trial following the administration of acupuncture and inactive mock laser. The study was embedded in a two-arm parallel design multicenter, randomized clinical trial, the Tennis Elbow Acupuncture-International Study-China, Hong Kong, Australia, Italy (TEA IS CHAI). Needle sensations were measured using a validated instrument, the Massachusetts General Hospital Acupuncture Sensation Spreading Scale. Ninety-six participants with lateral elbow pain were randomly allocated into two groups in a 1:1 ratio; the acupuncture treatment group (n = 47) and the mock laser control group (n = 49). Participants in both groups received the intervention at two acupoints, LI10 and LI11, consisting of 2 minutes of either standardized needle manipulation or mock laser at each acupoint with a rest period between each intervention period. Data were collected immediately following the interventions at the first and the ninth session within the clinical trial. Although participants in both groups perceived PSC radiating to similar sites along the upper limb, the frequency of the reported radiation sites among the two intervention groups for both radiation up the limb (p sensation sites recorded within the two study groups, the sensations were reported as radiating a greater distance down the forearm to the wrist compared to up the arm. Evaluation of PSC across the four study sites revealed a statistically significant difference in frequency of the reported radiation down the limb sites in each study group and radiation up the limb sites only in control group only (p

  7. PREFACE: 8th International Symposium of the Digital Earth (ISDE8)

    Science.gov (United States)

    2014-02-01

    th ISDE was due to commitments of many: authors, keynote speakers, session chairs, the organising committee, technical and scientific committee, student volunteers from Universiti Teknologi Malaysia (UTM) and Universiti Malaysia Sarawak (UNIMAS), and many others of various roles. We acknowledged all sponsors to 8th ISDE, namely Sarawak Convention Bureau, Malaysia Convention & Exhibition Bureau, and ESRI. We also thanked all exhibitors and contributors of the 8th ISDE: TSKAY Technologies Sdn Bhd, Coordinates-India, Taylor & Francis-Singapore, Beijing Space Eye-China, RS&GIS Consultancy, CRCSI-Australia, Jurupro Sdn Bhd, Inst of Remote Sensing and Digital Earth (RADI)-China, Department of Survey and Mapping Malaysia, SPECIM, Satellite Imaging (M) Sdn Bhd, IPASA-UTM, Sustainable Research Alliance-UTM, Sarawak Forest Department, International Society of Digital Earth-China, INSTeG-UTM, and UNIMAS. August 2013 Mazlan Hashim Samsudin Ahmad Yin Chai Wang Details of the organisation and committees are available in the PDF

  8. A novel start-up procedure for natural-circulation boiling water reactors

    International Nuclear Information System (INIS)

    Annalisa Manera; Frank Schaefer

    2005-01-01

    Full text of publication follows: The elimination of recirculation pumps and associated systems, as proposed for natural-circulation Boiling Water Reactors (BWRs), allow a great simplification in the design of BWRs. On the other hand, it has been shown both experimentally and analytically that such a new reactor configuration makes the system susceptible to thermal-hydraulic instabilities during the start-up phase (so-called flashing-induced instabilities). Therefore, appropriate start-up procedures have to be planned to avoid instabilities in natural-circulation BWRs. Not many proposals of start-up procedures for natural-circulation BWRs are reported in literature, but all authors agree on the fact that the system should be pressurized before the transition to two-phase circulation is allowed. Nayak [1] and Jiang and coauthors [2] proposed to externally pressurize the system by injecting in the pressure vessel respectively steam produced in a separate boiler or nitrogen. Once the pressure in the reactor vessel is high enough, the reactor power can be increased to achieve two-phase natural circulation. Unfortunately, the procedure suggested by Nayak requires an external boiler of adequate volume and power and the related connecting piping to the reactor vessel, while the procedure suggested by Jiang and coauthors requires an additional system for the nitrogen storage and the related connecting piping to the reactor vessel. The external pressurization does not accomplish to the requirements of simplicity that are at the very base of natural circulation BWRs design and it is thus not recommendable. Cheung and Rao [3] suggested a start-up procedure in which the reactor is first filled with water at 80 deg. C at a pressure of 0.55 bar. The reactor is made critical and is pressurized in conditions of single-phase circulation up to a pressure of 63 bar. At this pressure a sudden transition to two-phase operation is achieved by opening the MSIVs (Main Steam Isolation

  9. 3D Visualization Tools to Support Soil Management In Relation to Sustainable Agriculture and Ecosystem Services

    Science.gov (United States)

    Wang, Chen

    2017-04-01

    game engines as tools for supporting archaeology and the reconstruction of cultural heritage - the case-study of the Roman villa of Casal de Freiria, Journal of Archaeological Science, 38(12): 3296-3308. Wang, C., Miller, D.R., Brown I., Jiang Y., Castellazzi M, "Visualisation Techniques to Support Public Interpretation of Future Climate Change and Land Use Choices: A Case Study from N-E Scotland", International Journal of Digital Earth, Volume 9, Issue 6, pp.586-605, 2016. VLT, http://www.hutton.ac.uk/learning/exhibits/vlt Scotland's soil, http://www.soils-scotland.gov.uk/ Wang, C., Miller, D.R., Jiang Y., Donaldson-Selby, "Use of 3D Visualisation Tools for Representing Urban Greenspace Spatial Planning", 2015 IEEE International Conference on Information Science and Control Engineering Shanghai, China, April 24-26, 2015. Tobias, S., Buser, T., Buchecker, M. (2016) Does real-time visualization support local stakeholders in developing landscape visions? Environment and Planning B:Planning and Design, 43: 84¨ C197. Li.Y, Zhu. A-Xing, Shi. Z, Liu. J and Du. F, "Supplemental sampling for digital soil mapping based on prediction uncertainty from both the feature domain and the spatial domain", The Global Journal of Soil Science, Volume 284, pp 73-84, 2016. Warren-Kretzschmar. B and Haaren, C, "Communicating spatial planning decisions at the landscape and farm level with landscape visualization", Journal of Biogeosciences and Forestry, volume 7, pp 434-442, 2014.

  10. Determination of single-nucleotide polymorphism in the proximal promoter region of apolipoprotein M gene in coronary artery diseases

    Directory of Open Access Journals (Sweden)

    Lu Zheng

    2009-09-01

    Full Text Available Lu Zheng1, Guanghua Luo1, Xiaoying Zhang1, Jun Zhang1, Jiang Zhu1, Jiang Wei1, Qinfeng Mu1, Lujun Chen1, Peter Nilsson-Ehle2, Ning Xu21Comprehensive Laboratory, The Third Affiliated Hospital, Suzhou University, Changzhou China; 2Division of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lund University, Lund, SwedenObjective: It has been reported that single-nucleotide polymorphism (SNP in the proximal promoter region of apolipoprotein M (apoM gene may confer the risk in the development of type 2 diabetes (T2D and coronary artery disease (CAD in the Han Chinese. However, in a recent study demonstrated that plasma apoM level did not correlated to the coronary heart disease. In the present studies, we investigated the SNP T-778C of apoM gene in CAD patients and controls in the Han Chinese population. Moreover we examined whether serum apoM levels could be influenced by this promoter mutation.Material and methods: One hundred twenty-six CAD patients and 118 non-CAD patients were subjected in the present study. All patients were confirmed by the angiography. The genotyping of polymorphisms T-778C in apoM promoter was determined by real-time polymerase chain reaction. Serum apoM levels were semi-quantitatively determined by the dot-blotting analysis. Results: Distribution of apoM T-778C genotype in non-CAD patients was as following: 84.7% were T/T, 15.3% were T/C and 0.0% was C/C. T allele frequencies were 92.4% and C allele, 7.6%. In the CAD patients, 99 patients (78.6% had the T/T genotype, 25 patients (19.8% with T/C genotype and 2 patients (1.6% with C/C genotype. The allele frequency was 88.5% for the T allele and 11.5% for the C allele. There was no statistical significant difference of serum apoM levels found in these three genotypes.Conclusions: There was no significant difference in allele or genotype frequencies between CAD patients and non-CAD patients. Binary logistic regression analysis with adjustments for age

  11. International Conference on Applied Sciences (ICAS2013)

    International Nuclear Information System (INIS)

    Lemle, Ludovic Dan; Jiang, Yiwen

    2014-01-01

    volume of IOP Conference Series: Materials Science and Engineering. These papers present new researches in the various fields of materials engineering, mechanical engineering, computers engineering, mathematical engineering and clinical engineering. It's our great pleasure to present this volume of IOP Conference Series: Materials Science and Engineering to the scientific community to promote further researches in these areas. We sincerely hope that the papers published in this volume will contribute to the advancement of knowledge in the respective fields. All papers published in this volume of IOP Conference Series: Materials Science and Engineering (MSE) have been peer reviewed through processes administered by the editors of the ICAS2013 proceedings, Ludovic Dan Lemle and Yiwen Jiang. Special thanks should be directed to the organizing committee for their tremendous efforts in organizing the conference: General Chair Zhou Laixin, Military Economics Academy of Wuhan Co-chairs Du Qifa, Military Economics Academy of Wuhan Serban Viorel-Aurel, ''Politehnica'' University of Timişoara Fen Youmei, Wuhan University Lin Pinghua, Huazhong University of Science and Technology Members Lin Darong, Military Economics Academy of Wuhan Guo Zhonghou, Military Economics Academy of Wuhan Sun Honghong, Military Economics Academy of Wuhan Liu Dong, Military Economics Academy of Wuhan We thank the authors for their contributions and we would also like to express our gratitude everyone who contributed to this conference, especially for the generous support of the sponsor: micromega S C Micro-Mega HD S A Ludovic Dan Lemle and Yiwen Jiang Coordinators of the Scientific Committee of ICAS2013 Deatails of organizers and members of the scientific commmittee are available in the PDF

  12. International Conference on Applied Sciences (ICAS2013)

    Science.gov (United States)

    Lemle, Ludovic Dan; Jiang, Yiwen

    2014-03-01

    present new researches in the various fields of materials engineering, mechanical engineering, computers engineering, mathematical engineering and clinical engineering. It's our great pleasure to present this volume of IOP Conference Series: Materials Science and Engineering to the scientific community to promote further researches in these areas. We sincerely hope that the papers published in this volume will contribute to the advancement of knowledge in the respective fields. All papers published in this volume of IOP Conference Series: Materials Science and Engineering (MSE) have been peer reviewed through processes administered by the editors of the ICAS2013 proceedings, Ludovic Dan Lemle and Yiwen Jiang. Special thanks should be directed to the organizing committee for their tremendous efforts in organizing the conference: General Chair Zhou Laixin, Military Economics Academy of Wuhan Co-chairs Du Qifa, Military Economics Academy of Wuhan Serban Viorel-Aurel, ''Politehnica'' University of Timişoara Fen Youmei, Wuhan University Lin Pinghua, Huazhong University of Science and Technology Members Lin Darong, Military Economics Academy of Wuhan Guo Zhonghou, Military Economics Academy of Wuhan Sun Honghong, Military Economics Academy of Wuhan Liu Dong, Military Economics Academy of Wuhan We thank the authors for their contributions and we would also like to express our gratitude everyone who contributed to this conference, especially for the generous support of the sponsor: micromega S C Micro-Mega HD S A Ludovic Dan Lemle and Yiwen Jiang Coordinators of the Scientific Committee of ICAS2013 Deatails of organizers and members of the scientific commmittee are available in the PDF

  13. COMPARATIVELY STUDY OF VARIETIES OF VEGETABLE COWPEA OF DIFFERENT BREEDING PERIODS IN PRIMORIYE REGION

    Directory of Open Access Journals (Sweden)

    P. A. Chebukin

    2016-01-01

    cultivation in Primoriye region have been identified to meet all customers’ requirements. For small production and farming ‘Yin Jiang Yi Hao’, ‘Zi San Chi’, ‘Zi San Chi’, ‘Yu Yan San Chi Lv’, ‘Xue Long Yi Hao’, ‘Zao Chun’, ‘Xin Jang’, ‘Zao Chun Jiang Dou’ were recommended, while the accessions ‘k-818’ and ‘k-797’ from China, ‘s. Tan Kim’ from Vietnam were regarded for industrial proposes: cannery and deep freezing.

  14. A facile and sensitive peptide-modulating graphene oxide nanoribbon catalytic nanoplasmon analytical platform for human chorionic gonadotropin

    Directory of Open Access Journals (Sweden)

    Liang A

    2017-12-01

    Full Text Available Aihui Liang,1,2,* Chongning Li,1,2,* Dan Li,1,2,* Yanghe Luo,1–3 Guiqing Wen,1,2 Zhiliang Jiang1,2 1Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection, Guangxi Normal University, Ministry of Education, 2Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin University of Technology, Guilin, 3School of Food and Bioengineering, Hezhou University, Hezhou, China *These authors contributed equally to this work Abstract: The nanogold reaction between HAuCl4 and citrate is very slow, and the catalyst graphene oxide nanoribbon (GONR enhanced the nanoreaction greatly to produce gold nanoparticles (AuNPs that exhibited strong surface plasmon resonance (SPR absorption (Abs at 550 nm and resonance Rayleigh scattering (RRS at 550 nm. Upon addition of the peptide of human chorionic gonadotropin (hCG, the peptide could adsorb on the GONR surface, which inhibited the catalysis. When hCG was added, peptides were separated from the GONR surface due to the formation of stable peptide–hCG complex, which led to the activation of GONR catalytic effect. With the increase in hCG concentration, the RRS and Abs signal enhanced linearly. The enhanced RRS value showed a good linear relationship with hCG concentration in the range of 0.2–20 ng/mL, with a detection limit of 70 pg/mL. Accordingly, two new GONR catalytic RRS/Abs methods were established for detecting hCG in serum samples. Keywords: nanocatalysis, graphene oxide nanoribbon, peptide regulation, hCG, RRS

  15. Prognostic value of the C-reactive protein to albumin ratio: a novel inflammation-based prognostic indicator in osteosarcoma

    Directory of Open Access Journals (Sweden)

    Li YJ

    2017-11-01

    Full Text Available Yong-Jiang Li,1,* Kai Yao,2,* Min-Xun Lu,2 Wen-Biao Zhang,1 Cong Xiao,2 Chong-Qi Tu2 1Department of Oncology, 2Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, People’s Republic of China *These authors contributed equally to this work Abstract: The prognostic role of the C-reactive protein to albumin ratio (CRP/Alb ratio in patients with osteosarcoma has not been investigated. A total of 216 osteosarcoma patients were enrolled in the study. Univariate and multivariate survival analyses between the groups were performed and Kaplan–Meier analysis was conducted to plot the survival curves. Receiver operating characteristic curves were generated and areas under the curve (AUCs were compared to assess the discriminatory ability of the inflammation-based indicators, including CRP/Alb ratio, Glasgow prognostic score (GPS, neutrophil–lymphocyte ratio (NLR, and platelet–lymphocyte ratio (PLR. The optimal cutoff value was 0.210 for CRP/Alb ratio with a Youden index of 0.319. Higher values of CRP/Alb ratio were significantly associated with poorer overall survival in univariate (HR =2.62, 95% CI =1.70–4.03; P<0.001 and multivariate (HR =2.21, 95% CI =1.40–3.49; P=0.001 analyses. In addition, the CRP/Alb ratio had significantly higher AUC values compared with GPS (P=0.003, NLR (P<0.001, and PLR (P<0.001. The study demonstrated that the CRP/Alb ratio is an effective inflammation-based prognostic indicator in osteosarcoma, which potentially has a discriminatory ability superior to that of other inflammatory indicators including GPS, NLR, and PLR. Keywords: osteosarcoma, CRP to albumin ratio, prognosis

  16. Purification and in vitro antioxidant activities of tellurium-containing phycobiliproteins from tellurium-enriched Spirulina platensis

    Directory of Open Access Journals (Sweden)

    Yang F

    2014-10-01

    Full Text Available Fang Yang,1 Ka-Hing Wong,2 Yufeng Yang,3 Xiaoling Li,1 Jie Jiang,1 Wenjie Zheng,1 Hualian Wu,1 Tianfeng Chen1 1Department of Chemistry, Jinan University, Guangzhou, People’s Republic of China; 2Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, People’s Republic of China; 3Institute of Hydrobiology, College of Life Science and Technology, Jinan University, Guangzhou, People’s Republic of China Abstract: Tellurium-containing phycocyanin (Te-PC and allophycocyanin (Te-APC, two organic tellurium (Te species, were purified from tellurium-enriched Spirulina platensis by a fast protein liquid chromatographic method. It was found that the incorporation of Te into the peptides enhanced the antioxidant activities of both phycobiliproteins. With fractionation by ammonium sulfate precipitation and hydroxylapatite chromatography, Te-PC and Te-APC could be effectively separated with high purity, and Te concentrations were 611.1 and 625.3 µg g-1 protein in Te-PC and Te-APC, respectively. The subunits in the proteins were identified by using MALDI-TOF-TOF mass spectrometry. Te incorporation enhanced the antioxidant activities of both phycobiliproteins, as examined by 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid assay. Moreover, Te-PC and Te-APC showed dose-dependent protection on erythrocytes against the water-soluble free radical initiator 2,2'-azo(2-asmidinopropanedihydrochloride-induced hemolysis. In the hepatoprotective model, apoptotic cell death and nuclear condensation induced by tert-butyl hydroperoxide in HepG2 cells was significantly attenuated by Te-PC and Te-APC. Taken together, these results suggest that Te-PC and Te-APC are promising Te-containing proteins with application potential for treatment of diseases related to oxidative stress. Keywords: tellurium, phycocyanin, allophycocyanin, purification, antioxidant activity

  17. Management of osteoporosis with calcitriol in elderly Chinese patients: a systematic review

    Directory of Open Access Journals (Sweden)

    Liao RX

    2014-03-01

    Full Text Available Ruo-xi Liao, Miao Yu, Yan Jiang, Weibo XiaDepartment of Endocrinology, Key Laboratory of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, and Chinese Academy of Medical Sciences, Beijing, People's Republic of ChinaAbstract: Osteoporosis, a skeletal disorder characterized by a reduction in bone strength, is becoming a major public health problem in the People's Republic of China, with a rapid increase observed among the population. Chinese guidelines particularly recommend use of active vitamin D in managing osteoporosis. 1,25-(OH2D3 (calcitriol is an active vitamin D metabolite. It plays a role in many biological processes, especially in bone metabolism and muscle function, and is mediated by vitamin D receptors. Osteoporosis in elderly men and women is characterized by uncoupled bone remodeling, which is induced by sex hormone deficiencies, somatopause, vitamin D deficiency, reduced synthesis of D hormone, and lack of receptors or receptor affinity for D hormone in target organs. Reviewed here are six randomized controlled trials on calcitriol monotherapy and five on calcitriol therapy combined with other antiosteoporotic agents. Evidence from these trials shows that calcitriol monotherapy can improve bone mineral density in elderly osteoporotic Chinese patients but may be insufficient for long-term treatment. Calcitriol can also decrease bone turnover markers and bring about significant improvements in muscle strength. Further, calcitriol in combination with other therapeutic bone agents was shown to be well tolerated and capable of additional bone-preserving effects compared with use of calcitriol alone in areas including bone mineral density, bone turnover markers, bone pain improvement, and fracture incidence. Hypercalcemia and hypercalciuria, the most common side effects of calcitriol therapy, were not documented in the trials reviewed, and might have been the result of the low dosages used. One study showed that

  18. Lentivirus-mediated knockdown of NLK inhibits small-cell lung cancer growth and metastasis

    Directory of Open Access Journals (Sweden)

    Lv MT

    2016-11-01

    Full Text Available Mutian Lv,1 Yaming Li,1 Xin Tian,2 Shundong Dai,3,4 Jing Sun,5 Guojiang Jin,6 Shenyi Jiang7 1Department of Nuclear Medicine, 2Molecular Oncology Laboratory of Cancer Research Institute, The First Affiliated Hospital of China Medical University, 3Department of Pathology, The First Affiliated Hospital, College of Basic Medical Sciences of China Medical University, 4Department of Pathology, Institute of Pathology and Pathophysiology, 5Department of Immunology and Biotherapy, Liaoning Cancer Hospital and Institute, 6Department of Laboratory Medicine, 7Department of Rheumatology, The First Affiliated Hospital of China Medical University, Shenyang, People’s Republic of China Abstract: Nemo-like kinase (NLK, an evolutionarily conserved serine/threonine kinase, has been recognized as a critical regulator of various cancers. In this study, we investigated the role of NLK in human small-cell lung cancer (SCLC, which is the most aggressive form of lung cancer. NLK expression was evaluated by quantitative real-time polymerase chain reaction in 20 paired fresh SCLC tissue samples and found to be noticeably elevated in tumor tissues. Lentivirus-mediated RNAi efficiently suppressed NLK expression in NCI-H446 cells, resulting in a significant reduction in cell viability and proliferation in vitro. Moreover, knockdown of NLK led to cell cycle arrest at the S-phase via suppression of Cyclin A, CDK2, and CDC25A, which could contribute to cell growth inhibition. Furthermore, knockdown of NLK decreased the migration of NCI-H446 cells and downregulated matrix metalloproteinase 9. Treatment with NLK short hairpin RNA significantly reduced SCLC tumor growth in vivo. In conclusion, this study suggests that NLK plays an important role in the growth and metastasis of SCLC and may serve as a potential therapeutic target for the treatment of SCLC. Keywords: NLK, SCLC, RNAi, proliferation, migration

  19. Enhanced photocytotoxicity of curcumin delivered by solid lipid nanoparticles

    Directory of Open Access Journals (Sweden)

    Jiang S

    2016-12-01

    Full Text Available Shan Jiang,1 Rongrong Zhu,1 Xiaolie He,1 Jiao Wang,1 Mei Wang,1 Yechang Qian,2 Shilong Wang1 1Tenth People’s Hospital, School of Life Science and Technology, Tongji University, 2Department of Respiratory Disease, Baoshan District Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai, People’s Republic of China Abstract: Curcumin (Cur is a promising photosensitizer that could be used in photodynamic therapy. However, its poor solubility and hydrolytic instability limit its clinical use. The aim of the present study was to encapsulate Cur into solid lipid nanoparticles (SLNs in order to improve its therapeutic activity. The Cur-loaded SLNs (Cur-SLNs were prepared using an emulsification and low-temperature solidification method. The functions of Cur and Cur-SLNs were studied on the non-small cell lung cancer A549 cells for photodynamic therapy. The results revealed that Cur-SLNs induced ~2.27-fold toxicity higher than free Cur at a low concentration of 15 µM under light excitation, stocking more cell cycle at G2/M phase. Cur-SLNs could act as an efficient drug delivery system to increase the intracellular concentration of Cur and its accumulation in mitochondria; meanwhile, the hydrolytic stability of free Cur could be improved. Furthermore, Cur-SLNs exposed to 430 nm light could produce more reactive oxygen species to induce the disruption of mitochondrial membrane potential. Western blot analysis revealed that Cur-SLNs increased the expression of caspase-3, caspase-9 proteins and promoted the ratio of Bax/Bcl-2. Overall, the results from these studies demonstrated that the SLNs could enhance the phototoxic effects of Cur. Keywords: photodynamic therapy, curcumin, solid lipid nanoparticles, drug delivery, reactive oxygen species

  20. IL-13 regulates human nasal epithelial cell differentiation via H3K4me3 modification

    Directory of Open Access Journals (Sweden)

    Yu L

    2018-01-01

    Full Text Available Lei Yu,1 Na Li,1 Jisheng Zhang,2 Yan Jiang1 1Department of Otorhinolaryngology, 2Key Laboratory of Otolaryngology-Head and Neck Surgery, Affiliated Hospital of Qingdao University, Qingdao, China Introduction: Epigenetic regulation has been shown to play an important role in the development of inflammatory diseases, including chronic rhinosinusitis and nasal polyps. The latter are characterized by epithelial mis-differentiation and infiltration of inflammatory cytokines. H3K4me3 has been shown to be involved in regulating lineage commitment. However, the underlying mechanisms, especially in human nasal epithelial cells (HNEpC, remain underexplored. The objective of this study was to investigate the role of H3K4me3 in HNEpC differentiation treated with the Th2 cytokine IL-13. Patients and methods: The expression levels of mRNA and proteins were investigated using reverse transcription-polymerase chain reaction (RT-PCR assays and Western blot in nasal polyp tissues and human nasal epithelial cells respectively. We measured these levels of H3K4me3, MLL1 and targeted genes compared with control subjects.Results: We demonstrate that expression of H3K4me3 and its methyltransferase MLL1 was significantly upregulated in IL-13-treated HNEpC. This elevation was also observed in nasal polyps. Expression of cilia-related transcription factors FOXJ1 and DNAI2 decreased, while goblet cell-derived genes CLCA1 and MUC5a increased upon IL-13 treatment. Mechanistically, knockdown of MLL1 restored expression of these four genes induced by IL-13. Conclusion: These findings suggest that H3K4me3 is a critical regulator in control of nasal epithelial cell differentiation. MLL1 may be a potential therapeutic target for nasal inflammatory diseases. Keywords: IL-13, H3K4me3 modification, nasal epithelial cell, differentiation