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Sample records for cervical interbody fusion

  1. Single or double-level anterior interbody fusion techniques for cervical degenerative disc disease (Review)

    NARCIS (Netherlands)

    Jacobs, W.; Willems, P.C.P.H.; Limbeek, J. van; Bartels, R.H.M.A.; Pavlov, P.; Anderson, P.G.; Oner, C.

    2011-01-01

    BACKGROUND: The number of surgical techniques for decompression and solid interbody fusion as treatment for cervical spondylosis has increased rapidly, but the rationale for the choice between different techniques remains unclear. OBJECTIVES: To determine which technique of anterior interbody fusion

  2. Single or double-level anterior interbody fusion techniques for cervical degenerative disc disease

    NARCIS (Netherlands)

    Jacobs, Wilco; Willems, Paul C.; van Limbeek, Jacques; Bartels, Ronald; Pavlov, Paul; Anderson, Patricia G.; Oner, Cumhur

    2011-01-01

    Background The number of surgical techniques for decompression and solid interbody fusion as treatment for cervical spondylosis has increased rapidly, but the rationale for the choice between different techniques remains unclear. Objectives To determine which technique of anterior interbody fusion g

  3. Systematic review of anterior interbody fusion techniques for single- and double-level cervical degenerative disc disease

    NARCIS (Netherlands)

    Jacobs, W.; Willems, P.C.P.H.; Kruyt, M.; Limbeek, J. van; Anderson, P.G.; Pavlov, P.; Bartels, R.H.M.A.; Oner, C.

    2011-01-01

    STUDY DESIGN: A systematic review of randomized controlled trials. OBJECTIVE: To determine which technique of anterior cervical interbody fusion (ACIF) gives the best outcome in patients with cervical degenerative disc disease. SUMMARY OF BACKGROUND DATA: The number of surgical techniques for decomp

  4. The NEtherlands Cervical Kinematics (NECK) Trial. Cost-effectiveness of anterior cervical discectomy with or without interbody fusion and arthroplasty in the treatment of cervical disc herniation; A double-blind randomised multicenter study

    NARCIS (Netherlands)

    M.P. Arts (Mark); R. Brand (René); B.W. Koes (Bart); W.C. Peul (Wilco); M.E. van den Akker (Elske)

    2010-01-01

    textabstractBackground. Patients with cervical radicular syndrome due to disc herniation refractory to conservative treatment are offered surgical treatment. Anterior cervical discectomy is the standard procedure, often in combination with interbody fusion. Accelerated adjacent disc degeneration is

  5. The design of a cervical vertebra titanium plate-interbody fusion cage

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Objective: To study the biomechanical feature of a newly designed cervical vertebra internal fixation device and its clinical applications Methods: Some functional spinal units were fixed respectively with titanium plate, fusion cage and new device designed by ourselves, then a controlled biomechanical study including flexion, extension, torsion and lateral bending was performed and the results were analyzed. Results: As to the mechanical performance, fusion cage showed poor performance in extension test and so did the titanium plate in the distortion test. However, the new device showed good performance in every test. Conclusion: Both simple titanium plate fixation and simple fusion cage fixation have biomechanical defaults, but they are complementary. The titanium plate-interbody fusion cage avoids the defaults and has specific advantages.

  6. Extreme Lateral Interbody Fusion Procedure

    Medline Plus

    Full Text Available ... for spine surgery called XLIF, extreme lateral interbody fusion. Dr. Juan Uribe will perform the procedure. Dr. ... A better term would be extreme lateral interbody fusion. This is a procedure that has been performed ...

  7. Lateral Lumbar Interbody Fusion.

    Science.gov (United States)

    Pawar, Abhijit; Hughes, Alexander; Girardi, Federico; Sama, Andrew; Lebl, Darren; Cammisa, Frank

    2015-12-01

    The lateral lumbar interbody fusion (LLIF) is a relatively new technique that allows the surgeon to access the intervertebral space from a direct lateral approach either anterior to or through the psoas muscle. This approach provides an alternative to anterior lumbar interbody fusion with instrumentation, posterior lumbar interbody fusion, and transforaminal lumbar interbody fusion for anterior column support. LLIF is minimally invasive, safe, better structural support from the apophyseal ring, potential for coronal plane deformity correction, and indirect decompression, which have has made this technique popular. LLIF is currently being utilized for a variety of pathologies including but not limited to adult de novo lumbar scoliosis, central and foraminal stenosis, spondylolisthesis, and adjacent segment degeneration. Although early clinical outcomes have been good, the potential for significant neurological and vascular vertebral endplate complications exists. Nevertheless, LLIF is a promising technique with the potential to more effectively treat complex adult de novo scoliosis and achieve predictable fusion while avoiding the complications of traditional anterior surgery and posterior interbody techniques. PMID:26713134

  8. The NEtherlands Cervical Kinematics (NECK Trial. Cost-effectiveness of anterior cervical discectomy with or without interbody fusion and arthroplasty in the treatment of cervical disc herniation; a double-blind randomised multicenter study

    Directory of Open Access Journals (Sweden)

    van den Akker Elske

    2010-06-01

    Full Text Available Abstract Background Patients with cervical radicular syndrome due to disc herniation refractory to conservative treatment are offered surgical treatment. Anterior cervical discectomy is the standard procedure, often in combination with interbody fusion. Accelerated adjacent disc degeneration is a known entity on the long term. Recently, cervical disc prostheses are developed to maintain motion and possibly reduce the incidence of adjacent disc degeneration. A comparative cost-effectiveness study focused on adjacent segment degeneration and functional outcome has not been performed yet. We present the design of the NECK trial, a randomised study on cost-effectiveness of anterior cervical discectomy with or without interbody fusion and arthroplasty in patients with cervical disc herniation. Methods/Design Patients (age 18-65 years presenting with radicular signs due to single level cervical disc herniation lasting more than 8 weeks are included. Patients will be randomised into 3 groups: anterior discectomy only, anterior discectomy with interbody fusion, and anterior discectomy with disc prosthesis. The primary outcome measure is symptomatic adjacent disc degeneration at 2 and 5 years after surgery. Other outcome parameters will be the Neck Disability Index, perceived recovery, arm and neck pain, complications, re-operations, quality of life, job satisfaction, anxiety and depression assessment, medical consumption, absenteeism, and costs. The study is a randomised prospective multicenter trial, in which 3 surgical techniques are compared in a parallel group design. Patients and research nurses will be kept blinded of the allocated treatment for 2 years. The follow-up period is 5 years. Discussion Currently, anterior cervical discectomy with fusion is the golden standard in the surgical treatment of cervical disc herniation. Whether additional interbody fusion or disc prothesis is necessary and cost-effective will be determined by this trial

  9. Comparison of outcomes and safety of using hydroxyapatite granules as a substitute for autograft in cervical cages for anterior cervical discectomy and interbody fusion

    Directory of Open Access Journals (Sweden)

    Hosein Mashhadinezhad

    2014-03-01

    Full Text Available Background:   After cervical discectomy, autogenetic bone is packed into the cage to increase the rate of union between adjacent vertebral bodies, but donor site–related complications can still occur. In this study we evaluate the use   of hydroxyapatite granules as a substitute for autograft for interbody fusion.     Methods:   From November 2008 to November 2011, 236 patients participated in this study. Peek cages were packed with autologous bone grafts taken from the iliac crest in 112 patients and hydroxyapatite (HA granules in 124 patients.   Patients were followed for 12 months. The patients’ neurological signs, results, and complications were fully recorded   throughout the procedure. Radiological imaging was done to assess the fusion rate and settling ratio.     Results:   Formation of bony bridges at the third month was higher in the autograft group versus the granule group. However, there was no difference between both groups at the 12-month follow-up assessment. No difference (     P > 0.05   was found regarding improvement in neurological deficit as well as radicular pain and recovery rate between the two groups. Conclusions:   Interbody fusion cage containing HA granules proved to be an effective treatment for cervical spondylotic radiculopathy and/or myelopathy. Clinical and neurological outcome, radiographic measurement and fusion rate   in cage containing HA are similar and competitive with autograft packed cages.

  10. Comparison of outcomes and safety of using hydroxyapatite granules as a substitute for autograft in cervical cages for anterior cervical discectomy and interbody fusion

    Directory of Open Access Journals (Sweden)

    Hosein Mashhadinezhad

    2014-03-01

    Full Text Available Background:   After cervical discectomy, autogenetic bone is packed into the cage to increase the rate of union between adjacent vertebral bodies, but donor site–related complications can still occur. In this study we evaluate the use   of hydroxyapatite granules as a substitute for autograft for interbody fusion.     Methods:   From November 2008 to November 2011, 236 patients participated in this study. Peek cages were packed with autologous bone grafts taken from the iliac crest in 112 patients and hydroxyapatite (HA granules in 124 patients.   Patients were followed for 12 months. The patients’ neurological signs, results, and complications were fully recorded   throughout the procedure. Radiological imaging was done to assess the fusion rate and settling ratio.     Results:   Formation of bony bridges at the third month was higher in the autograft group versus the granule group. However, there was no difference between both groups at the 12-month follow-up assessment. No difference (     P > 0.05   was found regarding improvement in neurological deficit as well as radicular pain and recovery rate between the two groups. Conclusions:   Interbody fusion cage containing HA granules proved to be an effective treatment for cervical spondylotic radiculopathy and/or myelopathy. Clinical and neurological outcome, radiographic measurement and fusion rate   in cage containing HA are similar and competitive with autograft packed cages.    

  11. Surgical treatment of dysphagia after anterior cervical interbody fusion%前路颈椎融合术后吞咽困难的外科治疗

    Institute of Scientific and Technical Information of China (English)

    Fogel GR; McDonnell MF

    2005-01-01

    BACKGROUND CONTEXT: Dysphagia is a frequent complication after anterior cervical interbody fusion (ACIF). Although dysphagia usually improves over 6 months, it remains a significant and persistent problem for some patients. The etiology is poorly understood but has been reported to be associated with vocal cord paralysis, dislodgement of instrumentation and unidentified causes, such as hematoma, adhesion formation and denervation of the pharyngeal plexus. A surgical treatment of dysphagia after ACIF has not been reported.

  12. The VariLift® Interbody Fusion System: expandable, standalone interbody fusion

    Directory of Open Access Journals (Sweden)

    Emstad E

    2015-05-01

    Full Text Available Erik Emstad,1 Diana Cardenas del Monaco,1 Louis C Fielding,2 Jon E Block2 1Wenzel Spine, Inc., Austin, TX, 2The Jon Block Group, San Francisco, CA, USA Abstract: Intervertebral fusion cages have been in clinical use since the 1990s. Cages offer the benefits of bone graft containment, restored intervertebral and foraminal height, and a more repeatable, stable procedure compared to interbody fusion with graft material alone. Due to concerns regarding postoperative stability, loss of lordosis, and subsidence or migration of the implant, interbody cages are commonly used with supplemental fixation such as pedicle screw systems or anterior plates. While providing additional stability, supplemental fixation techniques increase operative time, exposure, cost, and morbidity. The VariLift® Interbody Fusion System (VariLift® system has been developed as a standalone solution to provide the benefits of intervertebral fusion cages without the requirement of supplemental fixation. The VariLift® system, FDA-cleared for standalone use in both the cervical and lumbar spine, is implanted in a minimal profile and then expanded in situ to provide segmental stability, restored lordosis, and a large graft chamber. Preclinical testing and analyses have found that the VariLift® System is durable, and reduces stresses that may contribute to subsidence and migration of other standalone interbody cages. Fifteen years of clinical development with the VariLift® system have demonstrated positive clinical outcomes, continued patient maintenance of segmental stability and lordosis, and no evidence of implant migration. The purpose of this report is to describe the VariLift® system, including implant characteristics, principles of operation, indications for use, patient selection criteria, surgical technique, postoperative care, preclinical testing, and clinical experience. The VariLift® System represents an improved surgical option for a stable interbody fusion without

  13. Anterior cervical reconstruction using interbody fusion cage with cervical compressive mini frame%椎间融合器配合颈椎压力固定器在颈椎前路重建中的应用

    Institute of Scientific and Technical Information of China (English)

    尹华; 李继春; 汤立; 程国林; 朱爱平

    2011-01-01

    目的 探讨颈椎间前路减压椎间融合器配合颈椎压力固定器治疗单间隙颈椎病及单间隙颈椎间盘突出症的短期临床疗效.方法 2008年1月至2009年4月对12例单间隙颈椎病及单间隙颈椎间盘突出症患者行颈前路减压同时采用椎间融合器配合颈椎压力固定器内固定.结果 所有患者获得随访,术后平均随访12 个月( 6~15个月),植骨均在6个月达到临床融合,无颈椎压力固定器松动等不良现象.术后疗效按JOA 评分,术前5~12 分,术后提高4~6分,脊髓功能平均改善率为85.2%.结论 颈椎前路减压术同时采用椎间融合器配合颈椎压力固定器可使颈椎得到即刻稳定,具有便捷省时、加压固定、弹性固定有利于骨性融合等优点.%Objective To retrospect and explore the nearly clinical effect of using interbody fusion cage with cervical compressivemini frame in cervical reconstruction.Methods From January 2008 to April 2009,12 patients with single gap cervical spondylosisor cervical disc herniation were treated through anterior cervical decompression by interbody fusion cage with cervical compressivemini frame.Results All cases were follow-up from 6 to 15 months (average 12 months ).After operation, there was radiographicevidence of fusion in all cases,there was no loosen or shift cervical compressive mini frame.The cases with incomplete paraplegiaimproved 4~6 scores according to JOA neurological criterial postperation.Conclusion Using interbody fusion cage with cervicalcompressive mini frame has many advantages, such as convenience,time efficient, compressive fixation and elastic fixation.

  14. Zero-P zero incisura anterior cervical interbody fusion fixation system (ACIF) in anterior cervical decompression and fusion applications%ACIF 在颈前路减压融合术的应用

    Institute of Scientific and Technical Information of China (English)

    汪冉; 王炤; 赵志芳

    2012-01-01

    ). Preoperative and postoperative differences were statistically sigr:ifican (P<0.05). After operation there was no infection, recurrent laryngeal nerve, the superior laryngeal nerves arid the vertebral artery injury, incision healing period, no revision operation. Conclusion Zero—P zero incisura anterior cervical interbody fusion fixation system (ACIF) can make the fusion segment to obtain Immediate stability, high rate of fusion, the curative effect is satisfied, with less trauma, less risk of nerve Injury, can prevent adjacent segment of ossification, the advantages of easy to operate.

  15. Hospital charges associated with "never events": comparison of anterior cervical discectomy and fusion, posterior lumbar interbody fusion, and lumbar laminectomy to total joint arthroplasty.

    Science.gov (United States)

    Daniels, Alan H; Kawaguchi, Satoshi; Contag, Alec G; Rastegar, Farbod; Waagmeester, Garrett; Anderson, Paul A; Arthur, Melanie; Hart, Robert A

    2016-08-01

    OBJECTIVE Beginning in 2008, the Centers for Medicare and Medicaid Service (CMS) determined that certain hospital-acquired adverse events such as surgical site infection (SSI) following spine surgery should never occur. The following year, they expanded the ruling to include deep vein thrombosis (DVT) and pulmonary embolism (PE) following total joint arthroplasty. Due to their ruling that "never events" are not the payers' responsibility, CMS insists that the costs of managing these complications be borne by hospitals and health care providers, rather than billings to health care payers for additional care required in their management. Data comparing the expected costs of such adverse events in patients undergoing spine and orthopedic surgery have not previously been reported. METHODS The California State Inpatient Database (CA-SID) from 2008 to 2009 was used for the analysis. All patients with primary procedure codes indicating anterior cervical discectomy and fusion (ACDF), posterior lumbar interbody fusion (PLIF), lumbar laminectomy (LL), total knee replacement (TKR), and total hip replacement (THR) were analyzed. Patients with diagnostic and/or treatment codes for DVT, PE, and SSI were separated from patients without these complication codes. Patients with more than 1 primary procedure code or more than 1 complication code were excluded. Median charges for treatment from primary surgery through 3 months postoperatively were calculated. RESULTS The incidence of the examined adverse events was lowest for ACDF (0.6% DVT, 0.1% PE, and 0.03% SSI) and highest for TKA (1.3% DVT, 0.3% PE, 0.6% SSI). Median inpatient charges for uncomplicated LL was $51,817, compared with $73,432 for ACDF, $143,601 for PLIF, $74,459 for THR, and $70,116 for TKR. Charges for patients with DVT ranged from $108,387 for TKR (1.5 times greater than index) to $313,536 for ACDF (4.3 times greater than index). Charges for patients with PE ranged from $127,958 for TKR (1.8 times greater than

  16. ISASS Policy Statement - Cervical Interbody

    OpenAIRE

    Singh, Kern; Qureshi, Sheeraz

    2014-01-01

    Morgan Lorio, MD, FACS, Chair, ISASS Task Force on Coding & Reimbursement In 2011, CPT code 22551 was revised to combine or bundle CPT codes 63075 and 22554 when both procedures were performed at the same site/same surgical session. The add on code +22552 is used to report each additional interspace. 2014 heralded a downward pressure on this now prime target code (for non-coverage?) 22551 through an egregious insurer attempt to redefine cervical arthrodesis, effectively removing spine surgeon...

  17. Anterior cervical allograft arthrodesis and instrumentation: Multilevel interbody grafting or strut graft reconstruction

    OpenAIRE

    Swank, M. L.; Lowery, G. L.; Bhat, A. L.; McDonough, R. F.

    1997-01-01

    This retrospective study evaluated a single surgeon's series of patients treated by multilevel cervical disc excision (two or three levels), allograft tricortical iliac crest arthrodesis, and anterior instrumentation. The objective of this retrospective study was to compare fusion success and clinical outcome between multilevel Smith-Robinson interbody grafting and tricortical iliac strut graft reconstruction, both supplemented with anterior instrumentation in the cervical spine. The incidenc...

  18. Transforaminal lumbar interbody fusion vs. posterolateral instrumented fusion

    DEFF Research Database (Denmark)

    Christensen, A; Høy, K; Bünger, C;

    2014-01-01

    -utility of transforaminal lumbar interbody fusion (TLIF) compared to posterolateral instrumented fusion (PLF) from the societal perspective. 100 Patients were randomized to TLIF or PLF (51/49) and followed for 2 years. Cost data were acquired from national registers, and outcomes were measured using the Oswestry Disability...

  19. The early-to-mid treatment efficacy of applying ROI interbody fusion cage in cervical spondylotic myelopathy%双嵌式颈椎融合器治疗脊髓型颈椎病早中期效果

    Institute of Scientific and Technical Information of China (English)

    李战友; 潘兵; 阮立奇; 张志敬

    2015-01-01

    Objective:To observe the clinical effect and radiological outcomes of ROI interbody fusion cage in cervical spondylotic myelopathy. Methods:21 patients were treated with lumbar disc excision and cervical vertebra fusion with ROI cage trans anterior approach. Clinical effect was evaluated by Japanese Orthopaedic Association (JOA) score for cervical function.Each patient underwent cervical anteroposterior and lateral radiographs,CT scanning before operation,at 3 days,3 months,and 6 months after operation to assess fusion effect. Intervertebral height was measured. The time of operation,in-traoperative blood loss and complication relative to opration were recorded. Results:As time goes on,the score of JOA was increased gradually after operation,and patients were all cured after 6 months. The fusion rate was 100%. No complication was found. Conclusion:Favorable early and midterm outcomes may be yielded in patients with cervical spondylotic myelopathy treated by anterior cervical discectomy and fusion with ROI interbody fusion cage.%目的:评估双嵌式颈椎融合器(ROI-C)治疗脊髓型颈椎病的临床疗效及影像学效果. 方法:2012年5月-2013年6月我科应用颈椎压力固定器对21名患者行颈椎前路减压椎间盘切除椎体融合术.应用JOA功能评分评价临床疗效,并于术前,术后3d、术后3个月、术后6个月行常规X线正侧位片检查,评估椎体间融合情况及椎间高度,并记录每例病例手术时间、出血量及手术相关并发症情况. 结果:JOA评分随时间顺序逐渐升高,6个月内所有病例椎间全部融合,椎间高度在术后3 d即显著恢复,3个月内下降,术后6个月趋于稳定.在随访期间,未发生手术相关并发症.结论:应用双嵌式颈椎融合器治疗脊髓型颈椎病可在早中期达到较好的临床疗效.

  20. Instrumented posterior lumbar interbody fusion (PLIF) with interbody fusion device (Cage) in degenerative disc disease (DDD): 3 years outcome.

    Science.gov (United States)

    Ahsan, M K; Hossain, M A; Sakeb, N; Khan, S I; Zaman, N

    2013-10-01

    This prospective interventional study carried out at Bangabandhu Sheikh Mujib Medical University and a private hospital in Dhaka, Bangladesh during the period from October 2003 to September 2011. Surgical treatment of degenerative disc disease (DDD) should aim to re-expand the interbody space and stabilize until fusion is complete. The present study conducted to find out the efficacy of using interbody fusion device (Cage) to achieve interbody space re-expansion and fusion in surgical management of DDD. We have performed the interventional study on 53 patients, 42 female and 11 male, with age between 40 to 67 years. All the patients were followed up for 36 to 60 months (average 48 months). Forty seven patients were with spondylolisthesis and 06 with desiccated disc. All subjects were evaluated with regard to immediate and long term complications, radiological fusion and interbody space re-expansion and maintenance. The clinical outcome (pain and disability) was scored by standard pre and postoperative questionnaires. Intrusion, extrusion and migration of the interbody fusion cage were also assessed. Forty seven patients were considered to have satisfactory outcome in at least 36 months follow up. Pseudoarthrosis developed in 04 cases and 06 patients developed complications. In this series posterior lumbar interbody fusion (PLIF) with interbody cage and instrumentation in DDD showed significant fusion rate and maintenance of interbody space. Satisfactory outcome observed in 88.68% cases.

  1. Extreme Lateral Interbody Fusion Procedure

    Medline Plus

    Full Text Available ... with an open procedure, what we call a standard open procedure, it is always a potential for ... and it's considered a lumber -- it's considered a standard lumbar spine fusion. The difference is the approach, ...

  2. Extreme Lateral Interbody Fusion Procedure

    Medline Plus

    Full Text Available ... he should allow for bone fusion in both gaps, those little spaces. Okay, so the question is, ... just placed in there. Again, you see the gaps, these gaps have a reason they are there. ...

  3. Extreme Lateral Interbody Fusion Procedure

    Medline Plus

    Full Text Available ... there, we just get access to the disk space and perform the fusion. And that's all done ... are placed to allow exposure to the disc space. This patient is suffering from severe lumbar spondylosis. ...

  4. Multiexpandable cage for minimally invasive posterior lumbar interbody fusion

    Science.gov (United States)

    Coe, Jeffrey D; Zucherman, James F; Kucharzyk, Donald W; Poelstra, Kornelis A; Miller, Larry E; Kunwar, Sandeep

    2016-01-01

    The increasing adoption of minimally invasive techniques for spine surgery in recent years has led to significant advancements in instrumentation for lumbar interbody fusion. Percutaneous pedicle screw fixation is now a mature technology, but the role of expandable cages is still evolving. The capability to deliver a multiexpandable interbody cage with a large footprint through a narrow surgical cannula represents a significant advancement in spinal surgery technology. The purpose of this report is to describe a multiexpandable lumbar interbody fusion cage, including implant characteristics, intended use, surgical technique, preclinical testing, and early clinical experience. Results to date suggest that the multiexpandable cage allows a less invasive approach to posterior/transforaminal lumbar interbody fusion surgery by minimizing iatrogenic risks associated with static or vertically expanding interbody prostheses while providing immediate vertebral height restoration, restoration of anatomic alignment, and excellent early-term clinical results. PMID:27729817

  5. Relation between radiological assessment and biomechanical stability of lumbar interbody fusion in a large animal model

    NARCIS (Netherlands)

    Kroeze, R. J.; van der Veen, A. J.; van Royen, B. J.; Bank, R. A.; Helder, M. N.; Smit, T. H.

    2013-01-01

    To relate the progress of vertebral segmental stability after interbody fusion surgery with radiological assessment of spinal fusion. Twenty goats received double-level interbody fusion and were followed for a period of 3, 6 and 12 months. After killing, interbody fusion was assessed radiographicall

  6. Relation between radiological assessment and biomechanical stability of lumbar interbody fusion in a large animal model

    NARCIS (Netherlands)

    R.J. Kroeze; A.J. van der Veen; B.J. van Royen; R.A. Bank; M.N. Helder; T.H. Smit

    2013-01-01

    Purpose To relate the progress of vertebral segmental stability after interbody fusion surgery with radiological assessment of spinal fusion. Methods Twenty goats received double-level interbody fusion and were followed for a period of 3, 6 and 12 months. After killing, interbody fusion was assessed

  7. ANALYSIS OF INTERBODY VERSUS POSTEROLATERAL FUSION FOR LUMBAR SPONDYLOSIS

    Directory of Open Access Journals (Sweden)

    Rodrigo Góes Medéa de Mendonça

    2015-12-01

    Full Text Available Objective : To evaluate and compare radiographic and clinical evaluation of patients undergoing interbody fusion versus posterolateral fusion of the lumbar spine. Methods : Retrospective study of patients diagnosed with lumbar spondylosis that were surgically treated in the period from 2012 to 2014. The results were observed by clinical evaluation by the Visual Analogue Scale (VAS for low back and leg pain. We evaluated functional results and quality of life through the application of the Oswestry Disability Index (ODI and the Short Form-36 (SF-36 questionnaires, respectively. The pre and postoperative condition were compared in Group 1 (interbody fusion and Group 2 (posterolateral fusion, in addition to evaluation of fusion by means of post-operative radiograph. Results : A total of 30 patients of 36 were eligible, 12 in Group 1 and 18 in Group 2. The mean follow-up was 10.1 months. Statistical analysis showed similar scores for back and leg pain VAS, SF-36 function scores and Oswestry between groups with interbody and posterolateral fusion, and compared within these groups regarding the pre- and postoperative condition, and found no statistical significance. The successful fusion was similar in both groups, with 11 of 12 patients in Group 1 showing bone fusion and 17 of 18 in Group 2 showing arthrodesis. Conclusion : No clinical or radiographic differences between patients who underwent posterolateral or interbody fusion were observed. Both methods showed improvement in functional outcome and pain reduction.

  8. Biomechanical stability of a bioabsorbable self-retaining polylactic acid/nano-sized β-tricalcium phosphate cervical spine interbody fusion device in single-level anterior cervical discectomy and fusion sheep models

    Directory of Open Access Journals (Sweden)

    Cao L

    2012-11-01

    Full Text Available Lu Cao,1 Ping-Guo Duan,1 Xi-Lei Li,1 Feng-Lai Yuan,3 Ming-Dong Zhao,2 Wu Che,1 Hui-Ren Wang,1 Jian Dong11Department of Orthopedic Surgery, Zhongshan Hospital, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, China; 2Department of Orthopedic Surgery, Jinshan Hospital, Fudan University, Shanghai, China; 3Affiliated Third Hospital of Nantong University, Wuxi, ChinaPurpose: The aim of this study was to investigate the biomechanical stability provided by a novel, polylactic acid/nano-sized, β-tricalcium phosphate, bioabsorbable, self-retaining cervical fusion cage (BCFC.Methods: Quasistatic nonconstraining torques (maximum 1.5 NM induced flexion, extension, lateral bending (±1.5 NM, and axial rotation (±1.5 NM on 32 sheep cervical spines (C2–C5. The motion segment C3–C4 was first tested intact; the following groups were tested after complete discectomy: autologous tricortical iliac crest bone graft, Medtronic–Wego polyetheretherketone (PEEK cage, Solis PEEK cage, and BCFC. The autologous bone graft group was tested with an anterior plate. The mean range of motion (ROM was calculated from the load-displacement curves.Results: BCFC significantly decreased ROM in lateral bending and axial rotation compared to other implants, and no significant difference in ROM between two types of PEEK cages and BCFC could be observed in flexion and extension. Anterior cervical plate (ACP significantly decreased ROM in flexion and extension, but no significant difference in ROM between BCFC and bone graft plus ACP could be determined in lateral bending and axial rotation.Conclusion: The BCFC device showed better stability to autologous tricortical iliac crest bone graft and PEEK cages in single-level anterior cervical discectomy and fusion models and thus may be a potential alternative to the current PEEK cages.Keywords: biomechanics, cervical spine, cages, bioabsorbable, sheep

  9. CHANGES IN RADIOGRAPHIC PARAMETERS AFTER MINIMALLY INVASIVE LUMBAR INTERBODY FUSION

    Directory of Open Access Journals (Sweden)

    Emiliano Vialle

    2015-12-01

    Full Text Available Objective : This study aims to evaluate changes in lumbosacral parameters after minimally invasive lumbar interbody fusion. The secondary aim was to evaluate whether interbody cage shape (crescent shaped or rectangular would influence the results. Method : Retrospective analysis of 70 patients who underwent one or two level lumbar interbody fusion through a minimally invasive posterolateral approach. This included midline preservation and unilateral facetectomy. Pre- and postoperative (three to six months postoperative radiographs were used for measuring lumbar lordosis (LL, segmental lordosis (SL at the level of interbody fusion, and sacral slope (SS. Further analyses divided the patients into Roussouly lumbar subgroups. Results : LL was significantly reduced after surgery (59o:39o, p=0.001 as well as the SS (33.8o:31.2o, p=0.05. SL did not change significantly (11.4:11.06, p=0.85. There were no significant differences when comparing patients who received crescent shaped cage (n=27 and rectangular cage (n=43. Hypolordotic patients (Roussouly types 1 and 2 had radiographic improvement in comparison to normolordotic and hyperlordotic groups (types 3 and 4. Conclusion : Minimally invasive lumbar interbody fusion caused reduction in lumbosacral parameters. Cage shape had no influence on the results.

  10. Application of Zero-P interbody fusion in degenerative disease at the adjacent segments after anterior cervical fusion%Zero-P椎间融合术在治疗颈前路融合术后相邻节段退变性疾病中的应用

    Institute of Scientific and Technical Information of China (English)

    程彩霞; 卢旭华; 谢宁; 郭翔; 郭群峰; 倪斌

    2012-01-01

    Objective To investigate the clinical outcomes of Zero-P interbody fusion in the treatment of degenerative disease at the adjacent segments after anterior cervical decompression and fusion with internal fixation. Methods Sixteen patients with degenerative diseases at adjacent segments after anterior cervical decompression and fusion with internal fixation received Zero-P anterior cervical interbody fusion. Japanese Orthopaedic Association ( JOA) scores were compared before and after the operation. Postoperative dysphagia and intervertebral fusion were observed. Results Postoperative JOA score was significantly increased as compared with preoperative score (P<0.05). No dysphagia occurred and all the patients obtained solid fusion. Conclusion The mid- and short-term curative effect is satisfactory for the Zero-P intervertebral fusion in the treatment of cervical degenerative disease in the adjacent segments after anterior cervical fusion.%目的 探讨采用Zero-P椎间融合术治疗颈前路减压融合内固定术后相邻节段退变性疾病的疗效.方法 对16例颈前路减压融合内固定术后发生相邻节段退变性疾病的患者采用Zero-P行颈前路椎间融合术,比较患者手术前后日本骨科学会(Japanese Orthopaedic Association,JOA)评分,观察患者术后吞咽困难发生情况及椎间融合情况.结果 患者术后JOA评分较术前提高,差异有统计学意义(P<0.05),未发生吞咽困难,所有患者均获得牢固融合.结论 采用Zero-P椎间融合术治疗颈前路融合术后相邻节段退变性疾病中短期疗效较好.

  11. Multiexpandable cage for minimally invasive posterior lumbar interbody fusion

    Directory of Open Access Journals (Sweden)

    Coe JD

    2016-09-01

    Full Text Available Jeffrey D Coe,1 James F Zucherman,2 Donald W Kucharzyk,3 Kornelis A Poelstra,4 Larry E Miller,5 Sandeep Kunwar,6 1Silicon Valley Spine Institute, Campbell, 2San Francisco Orthopaedic Surgeons, San Francisco, CA, 3Orthopaedic Pediatric and Spine, Crown Point, IN, 4Department of Surgery, Sacred Heart Hospital on the Emerald Coast, Miramar Beach, FL, 5Miller Scientific Consulting, Inc., Asheville, NC, 6Bell Neuroscience Institute, Washington Hospital Healthcare System, Fremont, CA, USA Abstract: The increasing adoption of minimally invasive techniques for spine surgery in recent years has led to significant advancements in instrumentation for lumbar interbody fusion. Percutaneous pedicle screw fixation is now a mature technology, but the role of expandable cages is still evolving. The capability to deliver a multiexpandable interbody cage with a large footprint through a narrow surgical cannula represents a significant advancement in spinal surgery technology. The purpose of this report is to describe a multiexpandable lumbar interbody fusion cage, including implant characteristics, intended use, surgical technique, preclinical testing, and early clinical experience. Results to date suggest that the multiexpandable cage allows a less invasive approach to posterior/transforaminal lumbar interbody fusion surgery by minimizing iatrogenic risks associated with static or vertically expanding interbody prostheses while providing immediate vertebral height restoration, restoration of anatomic alignment, and excellent early-term clinical results. Keywords: degenerative disc disease, expandable, low back pain, Luna

  12. Comparison of the different surgical approaches for lumbar interbody fusion.

    Science.gov (United States)

    Talia, Adrian J; Wong, Michael L; Lau, Hui C; Kaye, Andrew H

    2015-02-01

    This review will outline the history of spinal fusion. It will compare the different approaches currently in use for interbody fusion. A comparison of the techniques, including minimally invasive surgery and graft options will be included. Lumbar interbody fusion is a commonly performed surgical procedure for a variety of spinal disorders, especially degenerative disease. Currently this procedure is performed using anterior, lateral, transforaminal and posterior approaches. Minimally invasive techniques have been increasing in popularity in recent years. A posterior approach is frequently used and has good fusion rates and low complication rates but is limited by the thecal and nerve root retraction. The transforaminal interbody fusion avoids some of these complications and is therefore preferable in some situations, especially revision surgery. An anterior approach avoids the spinal cord and cauda equina all together, but has issues with visceral exposure complications. Lateral lumbar interbody fusion has a risk of lumbar plexus injury with dissection through the psoas muscle. Studies show less intraoperative blood loss for minimally invasive techniques, but there is no long-term data. Iliac crest is the gold standard for bone graft, although adjuncts such as bone morphogenetic proteins are being used more frequently, despite their controversial history. More high-level studies are needed to make generalisations regarding the outcomes of one technique compared with another.

  13. Lumbar interbody fusion: techniques, indications and comparison of interbody fusion options including PLIF, TLIF, MI-TLIF, OLIF/ATP, LLIF and ALIF.

    Science.gov (United States)

    Mobbs, Ralph J; Phan, Kevin; Malham, Greg; Seex, Kevin; Rao, Prashanth J

    2015-12-01

    Degenerative disc and facet joint disease of the lumbar spine is common in the ageing population, and is one of the most frequent causes of disability. Lumbar spondylosis may result in mechanical back pain, radicular and claudicant symptoms, reduced mobility and poor quality of life. Surgical interbody fusion of degenerative levels is an effective treatment option to stabilize the painful motion segment, and may provide indirect decompression of the neural elements, restore lordosis and correct deformity. The surgical options for interbody fusion of the lumbar spine include: posterior lumbar interbody fusion (PLIF), transforaminal lumbar interbody fusion (TLIF), minimally invasive transforaminal lumbar interbody fusion (MI-TLIF), oblique lumbar interbody fusion/anterior to psoas (OLIF/ATP), lateral lumbar interbody fusion (LLIF) and anterior lumbar interbody fusion (ALIF). The indications may include: discogenic/facetogenic low back pain, neurogenic claudication, radiculopathy due to foraminal stenosis, lumbar degenerative spinal deformity including symptomatic spondylolisthesis and degenerative scoliosis. In general, traditional posterior approaches are frequently used with acceptable fusion rates and low complication rates, however they are limited by thecal sac and nerve root retraction, along with iatrogenic injury to the paraspinal musculature and disruption of the posterior tension band. Minimally invasive (MIS) posterior approaches have evolved in an attempt to reduce approach related complications. Anterior approaches avoid the spinal canal, cauda equina and nerve roots, however have issues with approach related abdominal and vascular complications. In addition, lateral and OLIF techniques have potential risks to the lumbar plexus and psoas muscle. The present study aims firstly to comprehensively review the available literature and evidence for different lumbar interbody fusion (LIF) techniques. Secondly, we propose a set of recommendations and guidelines

  14. Minimal invasive transforaminal lumbar interbody fusion versus open transforaminal lumbar interbody fusion

    Science.gov (United States)

    Kulkarni, Arvind G; Bohra, Hussain; Dhruv, Abhilash; Sarraf, Abhishek; Bassi, Anupreet; Patil, Vishwanath M

    2016-01-01

    Background: The aim of the present prospective study is to evaluate whether the touted advantages of minimal invasive-transforaminal lumbar interbody fusion (MI-TLIF) translate into superior, equal, or inferior outcomes as compared to open-transforaminal lumbar interbody fusion (O-TLIF). This is the first study from the Indian subcontinent prospectively comparing the outcomes of MI-TLIF and O-TLIF. Materials and Methods: All consecutive cases of open and MI-TLIF were prospectively followed up. Single-level TLIF procedures for spondylolytic and degenerative conditions (degenerative spondylolisthesis, central disc herniations) operated between January 2011 and January 2013 were included. The pre and postoperative Oswestry Disability Index (ODI) and visual analog scale (VAS) for back pain and leg pain, length of hospital stay, operative time, radiation exposure, quantitative C-reactive protein (QCRP), and blood loss were compared between the two groups. The parameters were statistically analyzed (using IBM® SPSS® Statistics version 17). Results: 129 patients underwent TLIF procedure during the study period of which, 71 patients (46 MI-TLIF and 25 O-TLIF) fulfilled the inclusion criteria. Of these, a further 10 patients were excluded on account of insufficient data and/or no followup. The mean followup was 36.5 months (range 18-54 months). The duration of hospital stay (O-TLIF 5.84 days + 2.249, MI-TLIF 4.11 days + 1.8, P blood loss (open 358.8 ml, MI 111.81 ml, P group. On an average, 57.77 fluoroscopic exposures were required in MI-TLIF which was significantly higher than in O-TLIF (8.2). There was no statistically significant difference in the improvement in ODI and VAS scores in MI-TLIF and O-TLIF groups. The change in QCRP values preoperative and postoperative was significantly lower (P group than in O-TLIF group, indicating lesser tissue trauma. Conclusion: The results in MI TLIF are comparable with O-TLIF in terms of outcomes. The advantages of MI-TLIF are

  15. Complications and Morbidities of Mini-open Anterior Retroperitoneal Lumbar Interbody Fusion: Oblique Lumbar Interbody Fusion in 179 Patients

    OpenAIRE

    Silvestre, Clément; Mac-Thiong, Jean-Marc; Hilmi, Radwan; Roussouly, Pierre

    2012-01-01

    Study Design A retrospective study including 179 patients who underwent oblique lumbar interbody fusion (OLIF) at one institution. Purpose To report the complications associated with a minimally invasive technique of a retroperitoneal anterolateral approach to the lumbar spine. Overview of Literature Different approaches to the lumbar spine have been proposed, but they are associated with an increased risk of complications and a longer operation. Methods A total of 179 patients with previous ...

  16. Review of early clinical results and complications associated with oblique lumbar interbody fusion (OLIF).

    Science.gov (United States)

    Phan, Kevin; Maharaj, Monish; Assem, Yusuf; Mobbs, Ralph J

    2016-09-01

    Lumbar interbody fusion represents an effective surgical intervention for patients with lumbar degenerative diseases, spondylolisthesis, disc herniation, pseudoarthrosis and spinal deformities. Traditionally, conventional open anterior lumbar interbody fusion and posterior/transforaminal lumbar interbody fusion techniques have been employed with excellent results, but each with their own advantages and caveats. Most recently, the antero-oblique trajectory has been introduced, providing yet another corridor to access the lumbar spine. Termed the oblique lumbar interbody fusion, this approach accesses the spine between the anterior vessels and psoas muscles, avoiding both sets of structures to allow efficient clearance of the disc space and application of a large interbody device to afford distraction for foraminal decompression and endplate preparation for rapid and thorough fusion. This review aims to summarize the early clinical results and complications of this new technique and discusses potential future directions of research. PMID:27349468

  17. Theoretical model of a piezoelectric composite spinal fusion interbody implant.

    Science.gov (United States)

    Tobaben, Nicholas E; Domann, John P; Arnold, Paul M; Friis, Elizabeth A

    2014-04-01

    Failure rates of spinal fusion are high in smokers and diabetics. The authors are investigating the development of a piezoelectric composite biomaterial and interbody device design that could generate clinically relevant levels of electrical stimulation to help improve the rate of fusion for these patients. A lumped parameter model of the piezoelectric composite implant was developed based on a model that has been utilized to successfully predict power generation for piezoceramics. Seven variables (fiber material, matrix material, fiber volume fraction, fiber aspect ratio, implant cross-sectional area, implant thickness, and electrical load resistance) were parametrically analyzed to determine their effects on power generation within reasonable implant constraints. Influences of implant geometry and fiber aspect ratio were independent of material parameters. For a cyclic force of constant magnitude, implant thickness was directly and cross-sectional area inversely proportional to power generation potential. Fiber aspect ratios above 30 yielded maximum power generation potential while volume fractions above 15% showed superior performance. This investigation demonstrates the feasibility of using composite piezoelectric biomaterials in medical implants to generate therapeutic levels of direct current electrical stimulation. The piezoelectric spinal fusion interbody implant shows promise for helping increase success rates of spinal fusion.

  18. POSTERIOR LUMBAR INTERBODY FUSION AND INSTRUMENTED POSTEROLATERAL FUSION IN ADULT SPONDYLOLISTHESIS: ASSESSMENT AND CLINICAL OUTCOME

    Directory of Open Access Journals (Sweden)

    Rajarajan

    2015-11-01

    Full Text Available OBJECTIVE: Aim of this study is to assess and compare the outcomes of posterior lumbar interbody fusion (PLIF and posterolateral fusion (PLF in adult isthmic spondylosthesis. BACKGROUND: Posterolateral fusion has been considered the best method and widely been used for surgical treatment of adult spondylolisthesis.Superior results have subsequently been reported with interbody fusion with cages and posterior instrumentation MATERIALS AND METHODS: Thirty six patients with isthmic spondylolisthesis were operated. One group (20 patients had decompression and posterolateral fusion (PLF with a pedicle screw system; other group (16 patients was treated by decompression, posterior lumbar interbody fusion (PLIF and a Pedicle screw system. In both groups adequate decompression was done RESULTS: Seventy seven percent of the patients had a good result with (PLIF and 68 percent with posterolateral fusion (PLF. However there was no statistical difference in cases with low grade slipping, whereas the difference was significant for cases with high grade slipping. Fusion rate was 93% with (PLIF and 68% with (PLF, but without any significant incidence in the functional outcome. 78% has relief of sciatica and neurogenic claudication. CONCLUSION: Based on these findings we found that for high grade spondylolisthesis which requires reduction or if the disc space is still high posterior lumbar inter body fusion is preferable. For low grade spondylolisthesis or if the disc space is narrow posterolateral fusion is preferable. A successful result of fusion operation depends on adequate decompression which relieves radicular symptoms.

  19. Complication avoidance and management in anterior lumbar interbody fusion.

    Science.gov (United States)

    Than, Khoi D; Wang, Anthony C; Rahman, Shayan U; Wilson, Thomas J; Valdivia, Juan M; Park, Paul; La Marca, Frank

    2011-10-01

    The goal of this study was to review the literature to compare strategies for avoiding and treating complications from anterior lumbar interbody fusion (ALIF), and thus provide a comprehensive aid for spine surgeons. A thorough review of databases from the US National Library of Medicine and the National Institutes of Health was conducted. The complications of ALIF addressed in this paper include pseudarthrosis and subsidence, vascular injury, retrograde ejaculation, ileus, and lymphocele (chyloretroperitoneum). Strategies identified for improving fusion rates included the use of frozen rather than freeze-dried allograft, cage instrumentation, and bone morphogenetic protein. Lower cage heights appear to reduce the risk of subsidence. The most common vascular injury is venous laceration, which occurs less frequently when using nonthreaded interbody grafts such as iliac crest autograft or femoral ring allograft. Left iliac artery thrombosis is the most common arterial injury, and its occurrence can be minimized by intermittent release of retraction intraoperatively. The risk of retrograde ejaculation is significantly higher with laparoscopic approaches, and thus should be avoided in male patients. Despite precautionary measures, complications from ALIF may occur, but treatment options do exist. Bowel obstruction can be treated conservatively with neostigmine or with decompression. In cases of postoperative lymphocele, resolution can be attained by creating a peritoneal window. By recognizing ways to minimize complications, the spine surgeon can safely use ALIF procedures.

  20. Sagittal Balance Correction in Lateral Interbody Fusion for Degenerative Scoliosis

    Science.gov (United States)

    Gallizzi, Michael A.; Sheets, Charles; Smith, Benjamin T.; Isaacs, Robert E.; Eure, Megan; Brown, Christopher R.

    2016-01-01

    Background Sagittal balance restoration has been shown to be an important determinant of outcomes in corrective surgery for degenerative scoliosis. Lateral interbody fusion (LIF) is a less-invasive technique which permits the placement of a high lordosis interbody cage without risks associated with traditional anterior or transforaminal interbody techniques. Studies have shown improvement in lumbar lordosis following LIF, but only one other study has assessed sagittal balance in this population. The objective of this study is to evaluate the ability of LIF to restore sagittal balance in degenerative lumbar scoliosis. Methods Thirty-five patients who underwent LIF for degenerative thoracolumbar scoliosis from July 2013 to March 2014 by a single surgeon were included. Outcome measures included sagittal balance, lumbar lordosis, Cobb Angle, and segmental lordosis. Measures were evaluated pre-operative, immediately post-operatively, and at their last clinical follow-up. Repeated measures ANOVAs were used to assess the differences between pre-operative, first postoperative, and a follow-up visit. Results The average sagittal balance correction was not significantly different: 1.06cm from 5.79cm to 4.74cm forward. The average Cobb angle correction was 14.1 degrees from 21.6 to 5.5 degrees. The average change in global lumbar lordosis was found to be significantly different: 6.3 degrees from 28.9 to 35.2 degrees. Conclusions This study demonstrates that LIF reliably restores lordosis, but does not significantly improve sagittal balance. Despite this, patients had reliable improvement in pain and functionality suggesting that sagittal balance correction may not be as critical in scoliosis correction as previous studies have indicated. Clinical Relevance LIF does not significantly change sagittal balance; however, clinical improvement does not seem to be contingent upon sagittal balance correction in the degenerative scoliosis population. The DUHS IRB has determined this

  1. Sagittal Balance Correction in Lateral Interbody Fusion for Degenerative Scoliosis

    Science.gov (United States)

    Gallizzi, Michael A.; Sheets, Charles; Smith, Benjamin T.; Isaacs, Robert E.; Eure, Megan; Brown, Christopher R.

    2016-01-01

    Background Sagittal balance restoration has been shown to be an important determinant of outcomes in corrective surgery for degenerative scoliosis. Lateral interbody fusion (LIF) is a less-invasive technique which permits the placement of a high lordosis interbody cage without risks associated with traditional anterior or transforaminal interbody techniques. Studies have shown improvement in lumbar lordosis following LIF, but only one other study has assessed sagittal balance in this population. The objective of this study is to evaluate the ability of LIF to restore sagittal balance in degenerative lumbar scoliosis. Methods Thirty-five patients who underwent LIF for degenerative thoracolumbar scoliosis from July 2013 to March 2014 by a single surgeon were included. Outcome measures included sagittal balance, lumbar lordosis, Cobb Angle, and segmental lordosis. Measures were evaluated pre-operative, immediately post-operatively, and at their last clinical follow-up. Repeated measures ANOVAs were used to assess the differences between pre-operative, first postoperative, and a follow-up visit. Results The average sagittal balance correction was not significantly different: 1.06cm from 5.79cm to 4.74cm forward. The average Cobb angle correction was 14.1 degrees from 21.6 to 5.5 degrees. The average change in global lumbar lordosis was found to be significantly different: 6.3 degrees from 28.9 to 35.2 degrees. Conclusions This study demonstrates that LIF reliably restores lordosis, but does not significantly improve sagittal balance. Despite this, patients had reliable improvement in pain and functionality suggesting that sagittal balance correction may not be as critical in scoliosis correction as previous studies have indicated. Clinical Relevance LIF does not significantly change sagittal balance; however, clinical improvement does not seem to be contingent upon sagittal balance correction in the degenerative scoliosis population. The DUHS IRB has determined this

  2. Outcome of instrumented lumbar fusion for low grade spondylolisthesis; Evaluation of interbody fusion with & without cages

    Science.gov (United States)

    Fathy, Mostafa; Fahmy, Mohamed; Fakhri, Mazen; Aref, Khaled; Abdin, Khaled; Zidan, Ihab

    2010-01-01

    Object: The aim is to evalute the outcome of posterior lumbar interbody fusion with autologous bone graft versus titanium Cages, BAK system (Bagby – Kuslich, Spine Tech, Inc. Minneapolis, MN) for low grade spondyloisthesis (Grade1,11). Interbody cages have been developed to replace tricortical Interbody grafts in posterior lumbar interbody fusion (PLIF) procedures. The cages provide immediate post operative stability and facilitate bony union with cancellous bone packed in the cage itself. METHOD: We Evaluated 50 consecutive patients in whom surgery was performed between June 2000 to June 2003 in the Main Alexandria University Hospital at EGYPT. Twenty five patients were operated using autologous bone graft and 25 patients using the BAK cages. The neuro–radiologic al work up consisted of; plain X – ray lumbosacral spine including dynamic films preoperative and postoperative follow up; C.T lumbosacral spine and MRI lumbosacral spine. The surgery was performed at L4-5 level in 34 cases and at L5-S1 level in 16 cases. The median follow up was 15 months. RESULTS: Satisfactory fusion was obtained at all levels at a minimum one year follow – up. The fusion rate was 96% (24 patients) for the cage group and 80% (20 patients) for bone graft group however clinical improvement was 64% (16 patients) for those with bone graft group. CONCLUSION: A higher fusion rates and a better clinical outcome have been obtained by Instrumented PLIF with titanium cages that with bone graft. Inderbody fusion cages help to stabilize spainal segment primarily by distracting them as well as by allowing bone ingrowth and fusion. The procedure is safe and effective with 96% fusion rate and 76% overall Satisfactory rate. The use of cages help to distract the space between the vertebral bodies making the correction of the degree of spondylolisthesis easier. Long term follow up revealed better fusion rate and better realignment and less resorption with cages than with bone grafts. PMID

  3. Direct lateral interbody fusion (DLIF) at the lumbosacral junction L5-S1.

    Science.gov (United States)

    Shirzadi, Ali; Birch, Kurtis; Drazin, Doniel; Liu, John C; Acosta, Frank

    2012-07-01

    The direct lateral interbody fusion (DLIF), a minimally invasive lateral approach for placement of an interbody fusion device, does not require nerve root retraction or any contact with the great vessels and can lead to short operative times with little blood loss. Due to anatomical restrictions, this procedure has not been used at the lumbosacral (L5-S1) junction. Lumbosacral transitional vertebrae (LSTV), a structural anomaly of the lumbosacral spine associated with low back pain, can result in a level being wrongly identified pre-operatively due to misnumbering of the vertebral levels. To our knowledge, use of the DLIF graft in this patient is the first report of an interbody fusion graft being placed at the disc space between the LSTV and S1 via the transpsoas route. We present a review of the literature regarding the LSTV variation as well as the lateral placement of interbody fusion grafts at the lumbosacral junction.

  4. Healing properties of allograft from alendronate-treated animal in lumbar spine interbody cage fusion

    OpenAIRE

    Xue, Qingyun; Li, Haisheng; Zou, Xuenong; Bünger, Mathias; Egund, Niels; Lind, Martin; Christensen, Finn Bjarke; Bünger, Cody

    2004-01-01

    This study investigated the healing potential of allograft from bisphosphonate-treated animals in anterior lumbar spine interbody fusion. Three levels of anterior lumbar interbody fusion with Brantigan cages were performed in two groups of five landrace pigs. Empty Brantigan cages or cages filled with either autograft or allograft were located randomly at different levels. The allograft materials for the treatment group were taken from the pigs that had been fed with alendronate, 10 mg daily ...

  5. Analysis of Internet Information on Lateral Lumbar Interbody Fusion.

    Science.gov (United States)

    Belayneh, Rebekah; Mesfin, Addisu

    2016-07-01

    Lateral lumbar interbody fusion (LLIF) is a surgical technique that is being increasingly used. The authors' objective was to examine information on the Internet pertaining to the LLIF technique. An analysis was conducted of publicly accessible websites pertaining to LLIF. The following search engines were used: Google (www.google.com), Bing (www.bing.com), and Yahoo (www.yahoo.com). DuckDuckGo (www.duckduckgo.com) was an additional search engine used due to its emphasis on generating accurate and consistent results while protecting searchers' privacy and reducing advertisements. The top 35 websites providing information on LLIF from the 4 search engines were identified. A total of 140 websites were evaluated. Each web-site was categorized based on authorship (academic, private, medical industry, insurance company, other) and content of information. Using the search term lateral lumbar interbody fusion, 174,000 Google results, 112,000 Yahoo results, and 112,000 Bing results were obtained. DuckDuckGo does not display the number of results found for a search. From the top 140 websites collected from each website, 78 unique websites were identified. Websites were authored by a private medical group in 46.2% of the cases, an academic medical group in 26.9% of the cases, and the biomedical industry in 5.1% of the cases. Sixty-eight percent of websites reported indications, and 24.4% reported contraindications. Benefits of LLIF were reported by 69.2% of websites. Thirty-six percent of websites reported complications of LLIF. Overall, the quality of information regarding LLIF on the Internet is poor. Spine surgeons and spine societies can assist in improving the quality of the information on the Internet regarding LLIF. [Orthopedics. 2016; 39(4):e701-e707.]. PMID:27111081

  6. Analysis of Internet Information on Lateral Lumbar Interbody Fusion.

    Science.gov (United States)

    Belayneh, Rebekah; Mesfin, Addisu

    2016-07-01

    Lateral lumbar interbody fusion (LLIF) is a surgical technique that is being increasingly used. The authors' objective was to examine information on the Internet pertaining to the LLIF technique. An analysis was conducted of publicly accessible websites pertaining to LLIF. The following search engines were used: Google (www.google.com), Bing (www.bing.com), and Yahoo (www.yahoo.com). DuckDuckGo (www.duckduckgo.com) was an additional search engine used due to its emphasis on generating accurate and consistent results while protecting searchers' privacy and reducing advertisements. The top 35 websites providing information on LLIF from the 4 search engines were identified. A total of 140 websites were evaluated. Each web-site was categorized based on authorship (academic, private, medical industry, insurance company, other) and content of information. Using the search term lateral lumbar interbody fusion, 174,000 Google results, 112,000 Yahoo results, and 112,000 Bing results were obtained. DuckDuckGo does not display the number of results found for a search. From the top 140 websites collected from each website, 78 unique websites were identified. Websites were authored by a private medical group in 46.2% of the cases, an academic medical group in 26.9% of the cases, and the biomedical industry in 5.1% of the cases. Sixty-eight percent of websites reported indications, and 24.4% reported contraindications. Benefits of LLIF were reported by 69.2% of websites. Thirty-six percent of websites reported complications of LLIF. Overall, the quality of information regarding LLIF on the Internet is poor. Spine surgeons and spine societies can assist in improving the quality of the information on the Internet regarding LLIF. [Orthopedics. 2016; 39(4):e701-e707.].

  7. Repeated adjacent-segment degeneration after posterior lumbar interbody fusion.

    Science.gov (United States)

    Okuda, Shinya; Oda, Takenori; Yamasaki, Ryoji; Maeno, Takafumi; Iwasaki, Motoki

    2014-05-01

    One of the most important sequelae affecting long-term results is adjacent-segment degeneration (ASD) after posterior lumbar interbody fusion (PLIF). Although several reports have described the incidence rate, there have been no reports of repeated ASD. The purpose of this report was to describe 1 case of repeated ASD after PLIF. A 62-year-old woman with L-4 degenerative spondylolisthesis underwent PLIF at L4-5. At the second operation, L3-4 PLIF was performed for L-3 degenerative spondylolisthesis 6 years after the primary operation. At the third operation, L2-3 PLIF was performed for L-2 degenerative spondylolisthesis 1.5 years after the primary operation. Vertebral collapse of L-1 was detected 1 year after the third operation, and the collapse had progressed. At the fourth operation, 3 years after the third operation, vertebral column resection of L-1 and replacement of titanium mesh cages with pedicle screw fixation between T-4 and L-5 was performed. Although the patient's symptoms resolved after each operation, the time between surgeries shortened. The sacral slope decreased gradually although each PLIF achieved local lordosis at the fused segment.

  8. Outcomes of extended transforaminal lumbar interbody fusion for lumbar spondylosis.

    Science.gov (United States)

    Talia, Adrian J; Wong, Michael L; Lau, Hui C; Kaye, Andrew H

    2015-11-01

    This study aims to assess the results of extended transforaminal lumbar interbody fusion (TLIF) for a two surgeon, single institution series. In total, extended TLIF with bilateral decompression was performed in 57 patients. Pain, American Spinal Injury Association scores, patient demographics, body mass index (BMI), perioperative indices and radiographic measurements were recorded and analysed. The surgeries were performed between February 2011 and January 2014 on 38 women and 19 men. The mean patient age was 62.86 years, and the mean BMI was 30.31 kg/m(2). In 49 patients, spondylolisthesis was the primary indication. The mean intraoperative time was 284.65 min, and this decreased as the series progressed. The median length of stay was 5 days (range: 2-9). The surgical complication rate was 19.3%. Two patients died from cardiopulmonary complications. Single level TLIF was performed in 78.9% of the cohort, with L4/5 the most commonly fused level. Significant pain reduction was achieved from a mean (± standard deviation) preoperative visual analogue scale (VAS) of 8.28 ± 1.39 to 1.50 ± 1.05 at 12 months postoperatively. No patients deteriorated neurologically. Spondylolisthesis was significantly corrected from a preoperative mean of 6.82 mm to 2.80 mm postoperatively. Although there is a learning curve associated with the procedure, extended TLIF with bilateral facet joint removal and decompression appeared to be a safe and effective alternative to other fusion techniques, and our results were comparable to other published case series. The stabilisation and correction of spinal deformity reduces pain, aids neurologic recovery and improves quality of life. PMID:26358199

  9. Effects of platelet-rich plasma on subsidence of fiber porous titanium Cage for old dogs with anterior cervical interbody fusion%富血小板血浆对老龄犬纤维多孔钛颈椎椎间融合器沉降的影响

    Institute of Scientific and Technical Information of China (English)

    曹师锋; 谢宁; 宋鑫; 赵振国; 倪明; 焦鲲; 尹伟忠

    2015-01-01

    Objective To observe the effects of platelet-rich plasma (PRP) on subsidence of fiber porous titanium (FPT) Cage for old beagle dogs with anterior cervical interbody fusion.Methods Six old healthy beagle dogs (3 male and 3 female,weighing 12.5-15.0 kg,aged 7-9 years) were selected in this study.Peripheral venous blood from dog's forelimb was collected,PRP was prepared by double centrifugal methods,and blood platelet counts of peripheral venous blood and PRP were recorded.Then the dogs underwent anterior C4/5 and C5/6 discectomy and FPT Cage interbody fusion.FPT Cage was used alone at C4/5 segment,and at C5/6 segment,FPT Cage was augmented with PRP.The animals were sacrificed in 4 months after the surgery,and the subsidence of FPT Cage was evaluated by X-ray and Micro-CT examinations.Results Subsidence of FPT Cage was found at four C4/5 segments,other two FPT Cages at C4/5 segment showed anterior migration; No subsidence of FPT Cage was observed at six C5/6 segments,only one FPT Cage with anterior dislocation was found.Conclusion Compound PRP could reduce the subsidence of FPT Cage in old aged Beagle dogs with anterior cervical interbody fusion.%目的 观察富血小板血浆(PRP)对老龄比格犬颈椎前路椎间融合术纤维多孔钛椎间融合器(FPT Cage)沉降的影响.方法 选取6只7~9岁、12.5~15.0 kg的健康比格犬(雌雄各3只)作为实验动物.取比格犬前肢外周静脉血,采用二次离心法制备PRP,同时对外周静脉血及PRP进行血小板计数.行颈椎前路C4/5、C5/6椎间盘切除、FPT Cage椎间融合术,单纯使用未浸泡PRP的FPT Cage行C4/5椎间融合,采用浸泡激活后的PRP复合FPT Cage融合C5/6,术后4个月处死实验犬后行X线片及Micro-CT检查,观察C4/5、C5/6椎间融合器的沉降情况.结果 C4/5节段有4例出现不同程度的椎间融合器沉降,另2例出现Cage向前移位;C5/6节段未有椎间融合器发生沉降,仅1例出现Cage向前移位.结论 复合PRP可减少老龄比

  10. Minimally invasive transforaminal lumbar interbody fusion with percutaneous navigated guidewireless lumbosacral pedicle screw fixation.

    Science.gov (United States)

    Chen, Kevin S; Park, Paul

    2016-07-01

    This video details the minimally invasive approach for treatment of a symptomatic Grade II lytic spondylolisthesis with high-grade foraminal stenosis. In this procedure, the use of a navigated, guidewireless technique for percutaneous pedicle screw placement at the lumbosacral junction is highlighted following initial decompression and transforaminal interbody fusion. Key steps of the procedure are delineated that include positioning, exposure, technique for interbody fusion, intraoperative image acquisition, and use of a concise 2-step process for navigated screw placement without using guidewires. The video can be found here: https://youtu.be/2u6H4Pc_8To . PMID:27364422

  11. Minimally invasive L5-S1 oblique lumbar interbody fusion with anterior plate.

    Science.gov (United States)

    Pham, Martin H; Jakoi, Andre M; Hsieh, Patrick C

    2016-07-01

    Lumbar interbody fusion is an important technique for the treatment of degenerative disc disease and degenerative scoliosis. The oblique lumbar interbody fusion (OLIF) establishes a minimally invasive retroperitoneal exposure anterior to the psoas and lumbar plexus. In this video case presentation, the authors demonstrate the techniques of the OLIF at L5-S1 performed on a 69-year-old female with degenerative scoliosis as one component of an overall strategy for her deformity correction. The video can be found here: https://youtu.be/VMUYWKLAl0g . PMID:27364428

  12. Guideline update for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 11: interbody techniques for lumbar fusion.

    Science.gov (United States)

    Mummaneni, Praveen V; Dhall, Sanjay S; Eck, Jason C; Groff, Michael W; Ghogawala, Zoher; Watters, William C; Dailey, Andrew T; Resnick, Daniel K; Choudhri, Tanvir F; Sharan, Alok; Wang, Jeffrey C; Kaiser, Michael G

    2014-07-01

    Interbody fusion techniques have been promoted as an adjunct to lumbar fusion procedures in an effort to enhance fusion rates and potentially improve clinical outcome. The medical evidence continues to suggest that interbody techniques are associated with higher fusion rates compared with posterolateral lumbar fusion (PLF) in patients with degenerative spondylolisthesis who demonstrate preoperative instability. There is no conclusive evidence demonstrating improved clinical or radiographic outcomes based on the different interbody fusion techniques. The addition of a PLF when posterior or anterior interbody lumbar fusion is performed remains an option, although due to increased cost and complications, it is not recommended. No substantial clinical benefit has been demonstrated when a PLF is included with an interbody fusion. For lumbar degenerative disc disease without instability, there is moderate evidence that the standalone anterior lumbar interbody fusion (ALIF) has better clinical outcomes than the ALIF plus instrumented, open PLF. With regard to type of interbody spacer used, frozen allograft is associated with lower pseudarthrosis rates compared with freeze-dried allograft; however, this was not associated with a difference in clinical outcome.

  13. Healing properties of allograft from alendronate-treated animal in lumbar spine interbody cage fusion.

    Science.gov (United States)

    Xue, Qingyun; Li, Haisheng; Zou, Xuenong; Bünger, Mathias; Egund, Niels; Lind, Martin; Christensen, Finn Bjarke; Bünger, Cody

    2005-04-01

    This study investigated the healing potential of allograft from bisphosphonate-treated animals in anterior lumbar spine interbody fusion. Three levels of anterior lumbar interbody fusion with Brantigan cages were performed in two groups of five landrace pigs. Empty Brantigan cages or cages filled with either autograft or allograft were located randomly at different levels. The allograft materials for the treatment group were taken from the pigs that had been fed with alendronate, 10 mg daily for 3 months. The histological fusion rate was 2/5 in alendronate-treated allograft and 3/5 in non-treated allograft. The mean bone volume was 39% and 37.2% in alendronate-treated or non-treated allograft (NS), respectively. No statistical difference was found between the same grafted cage comparing two groups. The histological fusion rate was 7/10 in all autograft cage levels and 5/10 in combined allograft cage levels. No fusion was found at all in empty cage levels. With the numbers available, no statistically significant difference was found in histological fusion between autograft and allograft applications. There was a significant difference of mean bone volume between autograft (49.2%) and empty cage (27.5%) (P<0.01). In conclusion, this study did not demonstrate different healing properties of alendronate-treated and non-treated allograft for anterior lumbar interbody fusion in pigs. PMID:15248057

  14. Set screw fracture with cage dislocation after two-level transforaminal lumbar interbody fusion (TLIF): a case report

    OpenAIRE

    Leute, Philip Johannes Felix; Hammad, Ahmed; Hoffmann, Isabel; Hoppe, Sebastian; Klinger, Hans-Michael; Lakemeier, Stefan

    2015-01-01

    Introduction Transforaminal lumbar interbody fusion is a popular procedure used to achieve spondylodesis in patients with degenerative lumbar spinal diseases. We present a rare case of a patient with a set screw fracture with cage dislocation after an open transforaminal lumbar interbody fusion procedure. To the best of our knowledge, this case is the first of its kind to be reported. Case presentation A 44-year-old Caucasian woman attended a follow-up appointment at our hospital 3 months aft...

  15. Lateral Interbody Fusion for Treatment of Discogenic Low Back Pain: Minimally Invasive Surgical Techniques

    Directory of Open Access Journals (Sweden)

    Luis Marchi

    2012-01-01

    Full Text Available Low back pain is one of the most common ailments in the general population, which tends to increase in severity along with aging. While few patients have severe enough symptoms or underlying pathology to warrant surgical intervention, in those select cases treatment choices remain controversial and reimbursement is a substancial barrier to surgery. The object of this study was to examine outcomes of discogenic back pain without radiculopathy following minimally-invasive lateral interbody fusion. Twenty-two patients were treated at either one or two levels (28 total between L2 and 5. Discectomy and interbody fusion were performed using a minimallyinvasive retroperitoneal lateral transpsoas approach. Clinical and radiographic parameters were analyzed at standard pre- and postoperative intervals up to 24 months. Mean surgical duration was 72.1 minutes. Three patients underwent supplemental percutaneous pedicle screw instrumentation. Four (14.3% stand-alone levels experienced cage subsidence. Pain (VAS and disability (ODI improved markedly postoperatively and were maintained through 24 months. Segmental lordosis increased significantly and fusion was achieved in 93% of levels. In this series, isolated axial low back pain arising from degenerative disc disease was treated with minimally-invasive lateral interbody fusion in significant radiographic and clinical improvements, which were maintained through 24 months.

  16. Anterior cervical discectomy with or without fusion with ray titanium cage: a prospective randomized clinical study

    DEFF Research Database (Denmark)

    Hauerberg, J.; Kosteljanetz, M.; Bøge-Rasmussen, Torben;

    2008-01-01

    STUDY DESIGN: A prospective randomized clinical study. OBJECTIVE: To compare 2 surgical methods in the treatment of cervical radiculopathy caused by hard or soft disc herniation; namely, simple discectomy versus discectomy with an additional interbody fusion with a Ray titanium cage. SUMMARY...... of the nervous elements have been performed. To date, no randomized studies have compared simple discectomy with discectomy followed by an interbody fusion with a titanium cage. METHODS: Eighty-six patients with symptoms of nerve root compression at 1 level were randomly allocated to either discectomy followed...... by fusion with a Ray titanium cage (40 patients) or to discectomy alone (46 patients). Clinical and radiologic follow-up was performed 3, 12, and 24 months after surgery. RESULTS: There was no statistically significant difference between the 2 groups concerning self-reported satisfaction or severity of pain...

  17. Effect of Psychological Status on Outcome of Posterior Lumbar Interbody Fusion Surgery

    OpenAIRE

    Pollock, Raymond; Lakkol, Sandesh; Budithi, Chakra; Bhatia, Chandra; Krishna, Manoj

    2012-01-01

    Study Design Prospective longitudinal study. Purpose To determine if preoperative psychological status affects outcome in spinal surgery. Overview of Literature Low back pain is known to have a psychosomatic component. Increased bodily awareness (somatization) and depressive symptoms are two factors that may affect outcome. It is possible to measure these components using questionnaires. Methods Patients who underwent posterior interbody fusion (PLIF) surgery were assessed preoperatively and ...

  18. Simultaneous Lateral Interbody Fusion and Posterior Percutaneous Instrumentation: Early Experience and Technical Considerations

    Directory of Open Access Journals (Sweden)

    Doniel Drazin

    2015-01-01

    Full Text Available Lumbar fusion surgery involving lateral lumbar interbody graft insertion with posterior instrumentation is traditionally performed in two stages requiring repositioning. We describe a novel technique to complete the circumferential procedure simultaneously without patient repositioning. Twenty patients diagnosed with worsening back pain with/without radiculopathy who failed exhaustive conservative management were retrospectively reviewed. Ten patients with both procedures simultaneously from a single lateral approach and 10 control patients with lateral lumbar interbody fusion followed by repositioning and posterior percutaneous instrumentation were analyzed. Pars fractures, mobile grade 2 spondylolisthesis, and severe one-level degenerative disk disease were matched between the two groups. In the simultaneous group, avoiding repositioning leads to lower mean operative times: 130 minutes (versus control 190 minutes; p=0.009 and lower intraoperative blood loss: 108 mL (versus 93 mL; NS. Nonrepositioned patients were hospitalized for an average of 4.1 days (versus 3.8 days; NS. There was one complication in the control group requiring screw revision. Lateral interbody fusion and percutaneous posterior instrumentation are both readily accomplished in a single lateral decubitus position. In select patients with adequately sized pedicles, performing simultaneous procedures decreases operative time over sequential repositioning. Patient outcomes were excellent in the simultaneous group and comparable to procedures done sequentially.

  19. Imaging evaluation strategy of spinal interbody fusion%对脊柱椎间融合的影像学评价策略

    Institute of Scientific and Technical Information of China (English)

    高志强; 李洋; 罗飞

    2015-01-01

    背景:椎间融合是脊柱外科常用的修复方式,融合失败会导致多种并发症。对融合的正确判断非常重要。目前临床常使用影像学方法对融合情况进行判断。在评价融合时,X射线片、CT、MRI等检查手段拥有各自特殊的方法、特点,从而导致了其在敏感性、特异性等方面存在诸多差异。  目的:综述影像学检查手段在脊柱椎间融合评价中的研究进展。  方法:以英文关键词“lambar fusion,cervical fusion,interbody fusion,evaluation method”为检索词,在PubMed 数据库中进行检索。筛选出对椎间融合方法进行详细描述的文献进行综述,包含影像学手段的多种评价方法的对比研究。  结果与结论:依据纳入标准及排除标准,共入选40篇文献进行综述。X射线片和CT是使用最为广泛的判定手段,CT的判断结果更加可靠。MRI、骨扫描等其他影像学检查无法准确、直接的对脊柱融合情况进行评价。综合判断症状、体征和各种影像资料是更为合理的脊柱椎间融合评价策略。%BACKGROUND:Interbody fusion is widely used in spine surgeries. Failed fusion may cause many complications, so it is very important to evaluate fusion before surgery. Imaging methods are commonly used to evaluate fusion, including X ray, CT and MRI. Above methods have their own specific methods and characteristics, which cause their differences in sensibility and specificity. OBJECTIVE:To review the research progress of imaging methods in interbody fusion. METHODS:The English key words were“lambar fusion, cervical fusion, interbody fusion, evaluation method”in the PubMed database. The literatures with detailed description of interbody fusion were selected for further review, including comparative study on a variety of evaluation methods of imaging means. RESULTS AND CONCLUSION:According to the inclusion criteria and exclusion criteria, a total of 40

  20. Posterior lumbar interbody fusion using one diagonal fusion cage with transpedicular screw/rod fixation.

    Science.gov (United States)

    Zhao, Jie; Hou, Tiesheng; Wang, Xinwei; Ma, Shengzhong

    2003-04-01

    Posterior lumbar interbody fusion (PLIF) using threaded cages has gained wide popularity for lumbosacral spinal disease. Our biomechanical tests showed that PLIF using a single diagonal cage with unilateral facetectomy does add a little to spinal stability and provides equal or even higher postoperative stability than PLIF using two posterior cages with bilateral facetectomy. Studies also demonstrated that cages placed using a posterior approach did not cause the same increase in spinal stiffness seen with pedicle screw instrumentation, and we concluded that cages should not be used posteriorly without other forms of fixation. On the other hand, placement of two cages using a posterior approach does have the disadvantage of risk to the bilateral nerve roots. We therefore performed a prospective study to determine whether PLIF can be accomplished by utilizing a single diagonal fusion cage with the application of supplemental transpedicular screw/rod instrumentation. Twenty-seven patients underwent a PLIF using one single fusion cage (BAK, Sulzer Spine-Tech, Minneapolis, MN, USA) inserted posterolaterally and oriented anteromedially on the symptomatic side with unilateral facetectomy and at the same level supplemental fixation with a transpedicular screw/rod system. The internal fixation systems included 12 SOCON spinal systems (Aesculap AG, Germany) and 15 TSRH spinal systems (Medtronic Sofamor Danek, USA). The inclusion criteria were grade 1 to 2 lumbar isthmic spondylolisthesis, lumbar degenerative spondylolisthesis, and recurrent lumbar disc herniations with instability. Patients had at least 1 year of low back pain and/or unilateral sciatica and a severely restricted functional ability in individuals aged 28-55 years. Patients with more than grade 2 spondylolisthesis or adjacent-level degeneration were excluded from the study. Patients were clinically assessed prior to surgery by an independent assessor; they were then reassessed at 1, 3, 6, 12, 18, and 24

  1. Evaluation of ABM/P-15 versus autogenous bone in an ovine lumbar interbody fusion model.

    Science.gov (United States)

    Sherman, Blake P; Lindley, Emily M; Turner, A Simon; Seim, Howard B; Benedict, James; Burger, Evalina L; Patel, Vikas V

    2010-12-01

    A prospective, randomized study was performed in an ovine model to compare the efficacy of an anorganic bovine-derived hydroxyapatite matrix combined with a synthetic 15 amino acid residue (ABM/P-15) in facilitating lumbar interbody fusion when compared with autogenous bone harvested from the iliac crest. P-15 is a biomimetic to the cell-binding site of Type-I collagen for bone-forming cells. When combined with ABM, it creates the necessary scaffold to initiate cell invasion, binding, and subsequent osteogenesis. In this study, six adult ewes underwent anterior-lateral interbody fusion at L3/L4 and L4/L5 using PEEK interbody rings filled with autogenous bone at one level and ABM/P-15 at the other level and no additional instrumentation. Clinical CT scans were obtained at 3 and 6 months; micro-CT scans and histomorphometry analyses were performed after euthanization at 6 months. Clinical CT scan analysis showed that all autograft and ABM/P-15 treated levels had radiographically fused outside of the rings at the 3-month study time point. Although the clinical CT scans of the autograft treatment group showed significantly better fusion within the PEEK rings than ABM/P-15 at 3 months, micro-CT scans, clinical CT scans, and histomorphometric analyses showed there were no statistical differences between the two treatment groups at 6 months. Thus, ABM/P-15 was as successful as autogenous bone graft in producing lumbar spinal fusion in an ovine model, and it should be further evaluated in clinical studies.

  2. Intervertebral disk-like biphasic scaffold—demineralized bone matrix cylinder and poly(polycaprolactone triol malate)—for interbody spine fusion

    OpenAIRE

    Li Jin; Yuqing Wan; Shimer, Adam L.; Shen, Francis H.; Li, Xudong J

    2012-01-01

    Interbody fusion is an established procedure to preserve disk height and anterior fusion, but fusion with autografts, allografts, and metallic cages has its endogenous shortcomings. The objective of this study is to investigate whether a biphasic scaffold model, the native demineralized bone matrix cylinder in conjunction with degradable biomaterial poly(polycaprolactone triol malate), can be employed as a biological graft for interbody fusion. The poly(polycaprolactone triol malate) was synt...

  3. Fusion around cervical disc prosthesis: case report.

    NARCIS (Netherlands)

    Bartels, R.H.M.A.; Donk, R.

    2005-01-01

    OBJECTIVE AND IMPORTANCE: Cervical arthroplasty is a relatively new method to maintain motion after cervical anterior discectomy. Two cases are presented in which bony fusion occurred around a cervical disc prosthesis. CLINICAL PRESENTATION: A 30-year-old man and a 49-year-old woman underwent a righ

  4. Transforaminal lumbar interbody fusion versus posterolateral fusion in degenerative lumbar spondylosis

    Science.gov (United States)

    Zhang, Bin-Fei; Ge, Chao-Yuan; Zheng, Bo-Long; Hao, Ding-Jun

    2016-01-01

    Abstract Objective: The aim of the study was to evaluate the efficacy and safety of transforaminal lumbar interbody fusion (TLIF) versus posterolateral fusion (PLF) in degenerative lumbar spondylosis. Methods: A systematic literature review was performed to obtain randomized controlled trials (RCTs) and observational studies (OSs) of TLIF and PLF for degenerative lumbar spondylosis. Trials performed before November 2015 were retrieved from the Medline, EMBASE, Cochrane library, and Chinese databases. Data extraction and quality evaluation of the trials were performed independently by 2 investigators. A meta-analysis was performed using STATA version 12.0. Results: Two RCTs and 5 OSs of 630 patients were included. Of these subjects, 325 were in the TLIF and 305 were in the PLF group. Results showed that TLIF did not increase the fusion rate based on RCTs (relative risk [RR] = 1.06; 95% confidence interval [CI]: 0.95–1.18; P = 0.321), but increased it based on OSs (RR = 1.14; 95% CI: 1.07–1.23; P = 0.000) and overall (RR = 1.11; 95% CI: 1.05–1.18; P = 0.001) as compared with PLF. TLIF was able to improve the clinical outcomes based on 1 RCT (RR = 1.33; 95% CI: 1.11–1.59, P = 0.002) and overall (RR = 1.19; 95% CI: 1.07–1.33; P = 0.001), but not based on OSs (RR = 1.11; 95% CI: 0.97–1.27; P = 0.129) as compared with PLF. There were no differences between TLIF and PLF in terms of visual analogue scale, Oswestry Disability Index, reoperation, complications, duration of surgical procedure, blood loss, and hospitalization. Conclusions: In conclusion, evidence is not sufficient to support that TLIF provides higher fusion rate than PLF, and this poor evidence indicates that TLIF might improve only clinical outcomes. Higher quality, multicenter RCTs are needed to better define the role of TLIF and PLF. PMID:27749558

  5. Evaluation of ABM/P-15 versus autogenous bone in an ovine lumbar interbody fusion model

    OpenAIRE

    Sherman, Blake P.; Lindley, Emily M.; Turner, A. Simon; Seim III, Howard B.; Benedict, James; Burger, Evalina L; Patel, Vikas V.

    2010-01-01

    A prospective, randomized study was performed in an ovine model to compare the efficacy of an anorganic bovine-derived hydroxyapatite matrix combined with a synthetic 15 amino acid residue (ABM/P-15) in facilitating lumbar interbody fusion when compared with autogenous bone harvested from the iliac crest. P-15 is a biomimetic to the cell-binding site of Type-I collagen for bone-forming cells. When combined with ABM, it creates the necessary scaffold to initiate cell invasion, binding, and sub...

  6. Posterior interbody fusion using a diagonal cage with unilateral transpedicular screw fixation for lumbar stenosis.

    Science.gov (United States)

    Zhao, Jian; Zhang, Feng; Chen, Xiaoqing; Yao, Yu

    2011-03-01

    Few reports have described the combined use of unilateral pedicle screw fixation and interbody fusion for lumbar stenosis. We retrospectively reviewed 79 patients with lumbar stenosis. The rationale and effectiveness of unilateral pedicle screw fixation were studied from biomechanical and clinical perspectives, aiming to reduce stiffness of the implant. All patients were operated with posterior interbody fusion using a diagonal cage in combination with unilateral transpedicular screw fixation and had reached the 3-year follow-up interval after operation. The mean operating time was 115 minutes (range=95-150 min) and the mean estimated blood loss was 150 mL (range=100-200 mL). The mean duration of hospital stay was 10 days (range=7-15 days). Clinical outcomes were assessed prior to surgery and reassessed at intervals using Denis' pain and work scales. Fusion status was determined from X-rays and CT scans. At the final follow-up, the clinical results were satisfactory and patients showed significantly improved scores (pdiagonal cage with unilateral transpedicular fixation is an effective treatment for decompressive surgery for lumbar stenosis.

  7. Axial lumbar interbody fusion: a 6-year single-center experience

    Directory of Open Access Journals (Sweden)

    Zeilstra DJ

    2013-08-01

    Full Text Available Dick J Zeilstra,1 Larry E Miller,2,3 Jon E Block3 1Bergman Clinics, Naarden and NedSpine, Ede, The Netherlands; 2Miller Scientific Consulting, Inc, Arden, NC, USA; 3The Jon Block Group, San Francisco, CA, USA Introduction: The aim of this study is to report our 6-year single-center experience with L5–S1 axial lumbar interbody fusion (AxiaLIF. Methods: A total of 131 patients with symptomatic degenerative disc disease refractory to nonsurgical treatment were treated with AxiaLIF at L5–S1, and were followed for a minimum of 1 year (mean: 21 months. Main outcomes included back and leg pain severity, Oswestry Disability Index score, working status, analgesic medication use, patient satisfaction, and complications. Computed tomography was used to determine postoperative fusion status. Results: No intraoperative complications, including vascular, neural, urologic, or bowel injuries, were reported. Back and leg pain severity decreased by 51% and 42%, respectively, during the follow-up period (both P < 0.001. Back function scores improved 50% compared to baseline. Clinical success, defined as improvement ≥30%, was 67% for back pain severity, 65% for leg pain severity, and 71% for back function. The employment rate increased from 47% before surgery to 64% at final follow-up (P < 0.001. Less than one in four patients regularly used analgesic medications postsurgery. Patient satisfaction with the AxiaLIF procedure was 83%. The fusion rate was 87.8% at final follow-up. During follow-up, 17 (13.0% patients underwent 18 reoperations on the lumbar spine, including pedicle screw fixation (n = 10, total disc replacement of an uninvolved level (n = 3, facet screw fixation (n = 3, facet screw removal (n = 1, and interbody fusion at L4–L5 (n = 1. Eight (6.1% reoperations were at the index level. Conclusion: Single-level AxiaLIF is a safe and effective means to achieve lumbosacral fusion in patients with symptomatic degenerative disc disease. Keywords: Axia

  8. Neurological complications using a novel retractor system for direct lateral minimally invasive lumbar interbody fusion.

    Science.gov (United States)

    Sedra, Fady; Lee, Robert; Dominguez, Ignacio; Wilson, Lester

    2016-09-01

    We describe our experience using the RAVINE retractor (K2M, Leesburg, VA, USA) to gain access to the lateral aspect of the lumbar spine through a retroperitoneal approach. Postoperative neurological adverse events, utilising the mentioned retractor system, were recorded and analysed. We included 140 patients who underwent minimally invasive lateral lumbar interbody fusion (MI-LLIF) for degenerative spinal conditions between 2011 and 2015 at two major spinal centres. A total of 228 levels were treated, 35% one level, 40% two level, 20% three level and 5% 4 level surgeries. The L4/5 level was instrumented in 28% of cases. 12/140 patients had postoperative neurological complications. Immediately after surgery, 5% of patients (7/140) had transient symptoms in the thigh ranging from sensory loss, pain and paraesthesia, all of which recovered within 12weeks following surgery. There were five cases of femoral nerve palsy (3.6% - two ipsilateral and three contralateral), all of which recovered completely with no residual sensory or motor deficit within 6months. MI-LLIF done with help of the described retractor system has proved a safe and efficient way to achieve interbody fusion with minimal complications, mainly nerve related, that recovered quickly. Judicious use of the technique to access the L4/5 level is advised. PMID:27349467

  9. Clinical Outcomes of Extreme Lateral Interbody Fusion in the Treatment of Adult Degenerative Scoliosis

    Directory of Open Access Journals (Sweden)

    Adam M. Caputo

    2012-01-01

    Full Text Available Introduction. The use of extreme lateral interbody fusion (XLIF and other lateral access surgery is rapidly increasing in popularity. However, limited data is available regarding its use in scoliosis surgery. The objective of this study was to evaluate the clinical outcomes of adults with degenerative lumbar scoliosis treated with XLIF. Methods. Thirty consecutive patients with adult degenerative scoliosis treated by a single surgeon at a major academic institution were followed for an average of 14.3 months. Interbody fusion was completed using the XLIF technique with supplemental posterior instrumentation. Validated clinical outcome scores were obtained on patients preoperatively and at most recent follow-up. Complications were recorded. Results. The study group demonstrated improvement in multiple clinical outcome scores. Oswestry Disability Index scores improved from 24.8 to 19.0 (P < 0.001. Short Form-12 scores improved, although the change was not significant. Visual analog scores for back pain decreased from 6.8 to 4.6 (P < 0.001 while scores for leg pain decreased from 5.4 to 2.8 (P < 0.001. A total of six minor complications (20% were recorded, and two patients (6.7% required additional surgery. Conclusions. Based on the significant improvement in validated clinical outcome scores, XLIF is effective in the treatment of adult degenerative scoliosis.

  10. Diagnosing Cervical Fusion: A Comprehensive Literature Review

    OpenAIRE

    Sethi, Nanin; Devney, James; Steiner, Holly L.; Riew, K. Daniel

    2008-01-01

    Study Design Comprehensive literature review. Purpose To document the criteria for fusion utilized in these studies to determine if a consensus on the definition of a solid fusion exists. Overview of Literature Numerous studies have reported on fusion rates following anterior cervical arthrodesis. There is a wide discrepancy in the fusion rates in these studies. While factors such as graft type, Instrumentation, and technique play a factor in fusion rate, another reason for the difference may...

  11. Thoracolumbar fracture dislocations treated by posterior reduction interbody fusion and segmental instrumentation

    Directory of Open Access Journals (Sweden)

    Xiao-Bin Wang

    2014-01-01

    Materials and Methods: A retrospective review of 30 patients who had sustained fracture dislocation of the spine and underwent single stage posterior surgery between January 2007 and December 2011 was performed. All the patients underwent single stage posterior pedicle screw fixation, decompression and interbody fusion. Demographic data, medical records and radiographic images were reviewed thoroughly. Results: Ten females and 20 males with a mean age of 39.5 years were included in this study. Based on the AO classification, 13 cases were Type B1, 4 cases were B2, 4 were C1, 6 were C2 and 3 cases were C3. The average time of the surgical procedure was 220 min and the average blood loss was 550 mL. All of the patients were followed up for at least 2 years, with an average of 38 months. The mean preoperative kyphosis was 14.4° and reduced to -1.1° postoperatively. At the final followup, the mean kyphosis was 0.2°. The loss of correction was small (1.3° with no significant difference compared to postoperative kyphotic angle (P = 0.069. Twenty seven patients (90% achieved definitive bone fusion on X-ray or computed tomography imaging within 1 year followup. The other three patients were suspected possible pseudarthrosis. They remained asymptomatic without hardware failure or local pain at the last followup. Conclusion: Single stage posterior reduction using segmental pedicle screw instrumentation, combined with decompression and interbody fusion for the treatment of thoracic or lumbar fracture-dislocations is a safe, less traumatic and reliable technique. This procedure can achieve effective reduction, sagittal angle correction and solid fusion.

  12. Stand-Alone Lateral Interbody Fusion for the Treatment of Low-Grade Degenerative Spondylolisthesis

    Directory of Open Access Journals (Sweden)

    Luis Marchi

    2012-01-01

    Full Text Available The purpose of this paper was to investigate the stand-alone lateral interbody fusion as a minimally invasive option for the treatment of low-grade degenerative spondylolisthesis with a minimum 24-month followup. Prospective nonrandomized observational single-center study. 52 consecutive patients (67.6±10 y/o; 73.1% female; 27.4±3.4 BMI with single-level grade I/II single-level degenerative spondylolisthesis without significant spine instability were included. Fusion procedures were performed as retroperitoneal lateral transpsoas interbody fusions without screw supplementation. The procedures were performed in average 73.2 minutes and with less than 50cc blood loss. VAS and Oswestry scores showed lasting improvements in clinical outcomes (60% and 54.5% change, resp.. The vertebral slippage was reduced in 90.4% of cases from mean values of 15.1% preoperatively to 7.4% at 6-week followup (P<0.001 and was maintained through 24 months (7.1%, P<0.001. Segmental lordosis (P<0.001 and disc height (P<0.001 were improved in postop evaluations. Cage subsidence occurred in 9/52 cases (17% and 7/52 cases (13% spine levels needed revision surgery. At the 24-month evaluation, solid fusion was observed in 86.5% of the levels treated. The minimally invasive lateral approach has been shown to be a safe and reproducible technique to treat low-grade degenerative spondylolisthesis.

  13. Comparison of the extraction force of different interbody graft fixation at cervical vertebra after anterior cervical decompression%颈椎间不同植入物拔出载荷的比较

    Institute of Scientific and Technical Information of China (English)

    刘锦波; 唐天驷; 杨惠林

    2001-01-01

    目的:比较颈前路减压后分别植入钛合金螺纹融合支架、异体骨螺纹融合支架和自体髂骨的拔出载荷。方法:以人尸体颈椎为标本,颈前路环锯减压后,分别植入钛合金螺纹融合支架、异体骨螺纹融合支架和自体髂骨,测试以上植入物的最大拔出载荷。结果:减压后植入钛合金螺纹融合支架、异体骨螺纹融合支架、自体骼骨的最大拔出载荷分别为(114.7±23.3)、 (101.5±15.7)、 (58.7±8.3)N。结论:Cloward术减压后,钛合金螺纹融合支架、异体骨螺纹融合支架拔出载荷均大于植入自体髂骨。%Objective:To compare the extraction force of different interbody graft fixation at C4 and C5 after cervical decompression with the method of Cloward.Methods:Cervical vertebra was operated at C4 and C5 using orifice through anterior approach.The extraction force was measured after the allograft threaded fusion cage,titanium threaded fusion cage and autograft iliac bone graft were inserted separately into the interbody space.Results:The extraction force of titanium threaded fusion cage,allograft threaded fusion cage and autograft iliac bone graft were 114.0±23.3N and 101.5±15.7N and 58.7±8.3N respectively.Conclusion:Measured with the method of Cloward,the extraction forces of the allograft threaded fusion cage and titanium threaded fusion cage at C4 and C5 are bigger than that of autograft iliac bone graft after cervical decompression.

  14. Anterior Cervical Discectomy and Fusion with Plating

    Medline Plus

    Full Text Available ... Cervical Discectomy and Fusion with Plating Broward Health Medical Center Fort Lauderdale, FL November 17, 2011 I' ... the Spine Care Center here at North Broward Medical Center. And today we're operating on an ...

  15. Anterior Cervical Discectomy and Fusion with Plating

    Medline Plus

    Full Text Available Anterior Cervical Discectomy and Fusion with Plating Broward Health Medical Center Fort Lauderdale, FL November 17, 2011 I'm Dr. Matthew Moore, head of the Spine Care Center here at North Broward Medical Center. And ...

  16. Is posterior fusion necessary with laminectomy in the cervical spine?

    OpenAIRE

    McAllister, Beck D.; Rebholz, Brandon J.; Wang, Jeffery C.

    2012-01-01

    Background: Cervical decompressive laminectomy is a common procedure for addressing multilevel cervical spine pathology. The most common reasons for performing simultaneous posterior cervical fusion include the prevention of progressive postlaminectomy kyphotic deformity or other types of instability which can contribute to late neurological deterioration. Methods: The medical literature (Pub Med with MeSH) concerning cervical laminectomy, posterior cervical fusion, and complications of lamin...

  17. Treatment of Spinal Tuberculosis by Debridement, Interbody Fusion and Internal Fixation via Posterior Approach Only.

    Science.gov (United States)

    Tang, Ming-xing; Zhang, Hong-qi; Wang, Yu-xiang; Guo, Chao-feng; Liu, Jin-yang

    2016-02-01

    Surgical treatment for spinal tuberculosis includes focal tuberculosis debridement, segmental stability reconstruction, neural decompression and kyphotic deformity correction. For the lesions mainly involved anterior and middle column of the spine, anterior operation of debridement and fusion with internal fixation has been becoming the most frequently used surgical technique for the spinal tuberculosis. However, high risk of structural damage might relate with anterior surgery, such as damage in lungs, heart, kidney, ureter and bowel, and the deformity correction is also limited. Due to the organs are in the front of spine, there are less complications in posterior approach. Spinal pedicle screw passes through the spinal three-column structure, which provides more powerful orthopedic forces compared with the vertebral body screw, and the kyphotic deformity correction effect is better in posterior approach. In this paper, we report a 68-year-old male patient with thoracic tuberculosis who underwent surgical treatment by debridement, interbody fusion and internal fixation via posterior approach only. The patient was placed in prone position under general anesthesia. Posterior midline incision was performed, and the posterior spinal construction was exposed. Then place pedicle screw, and fix one side rod temporarily. Make the side of more bone destruction and larger abscess as lesion debridement side. Resect the unilateral facet joint, and retain contralateral structure integrity. Protect the spinal cord, nerve root. Clear sequestrum, necrotic tissue, abscess of paravertebral and intervertebral space. Specially designed titanium mesh cages or bone blocks were implanted into interbody. Fix both side rods and compress both sides to make the mesh cages and bone blocks tight. Reconstruct posterior column structure with allogeneic bone and autologous bone. Using this technique, the procedures of debridement, spinal cord decompression, deformity correction, bone grafting

  18. A meta-analysis of unilateral versus bilateral pedicle screw fixation in minimally invasive lumbar interbody fusion.

    Directory of Open Access Journals (Sweden)

    Zheng Liu

    Full Text Available STUDY DESIGN: Meta-analysis. BACKGROUND: Bilateral pedicle screw fixation (PS after lumbar interbody fusion is a widely accepted method of managing various spinal diseases. Recently, unilateral PS fixation has been reported as effective as bilateral PS fixation. This meta-analysis aimed to comparatively assess the efficacy and safety of unilateral PS fixation and bilateral PS fixation in the minimally invasive (MIS lumbar interbody fusion for one-level degenerative lumbar spine disease. METHODS: MEDLINE/PubMed, EMBASE, BIOSIS Previews, and Cochrane Library were searched through March 30, 2014. Randomized controlled trials (RCTs and controlled clinical trials (CCTs on unilateral versus bilateral PS fixation in MIS lumbar interbody fusion that met the inclusion criteria and the methodological quality standard were retrieved and reviewed. Data on participant characteristics, interventions, follow-up period, and outcomes were extracted from the included studies and analyzed by Review Manager 5.2. RESULTS: Six studies (5 RCTs and 1 CCT involving 298 patients were selected. There were no significant differences between unilateral and bilateral PS fixation procedures in fusion rate, complications, visual analogue score (VAS for leg pain, VAS for back pain, Oswestry disability index (ODI. Both fixation procedures had similar length of hospital stay (MD = 0.38, 95% CI = -0.83 to 1.58; P = 0.54. In contrast, bilateral PS fixation was associated with significantly more intra-operative blood loss (P = 0.002 and significantly longer operation time (P = 0.02 as compared with unilateral PS fixation. CONCLUSIONS: Unilateral PS fixation appears as effective and safe as bilateral PS fixation in MIS lumbar interbody fusion but requires less operative time and causes less blood loss, thus offering a simple alternative approach for one-level lumbar degenerative disease.

  19. Posterior Decompression, Lumber Interbody Fusion and Internal Fixation in the Treatment of Upper Lumbar Intervertebral Disc Herniation

    Directory of Open Access Journals (Sweden)

    DONG Zhan

    2014-12-01

    Full Text Available Objective: To assess the clinical outcomes of posterior decompression, interbody fusion and internal fixationfor the treatment of the upper lumbar intervertebral disc herniation. Methods: Twelve patients with the upper lumbar intervertebral disc herniation were treated by posterior decompression, interbosy fusion and internal fixation. The time of the operation, the amount of bleeding and the clinical efficacy were evaluated. Results: The time of operation was (143±36 min and the amount of bleeding during operation was (331.5±47.9 mL. There was no spinal cord and injuries, nerve injury, epidural damage and leakage of cerebrospinal fluid. All patients were followed up for 10~19 months with the average being 12.6 months. The functional scoring of Japanese Orthopedic Association (JOA before the operation was (11.4±3.3 scores and final score after follow-up was (22.9±3.1 scores and there were statistical difference (P<0.01. Lumber interbody fusion of all patients completed successfully and the good rate after the operation was 91.7%. Conclusion: Posterior decompression, interbody fusion and internal fixation for the treatment of the upper lumbar intervertebral disc herniation was characterized by full exposure, safety and significant efficacy.

  20. Application of tridimensional intravertebral bone graft combined with AxiaLIF technique in lumbar interbody fusion

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    Xiangdong Duan

    2009-05-01

    Full Text Available "nLumbar interbody fusion techniques are becoming more and more minimally invasive. AxiaLIF technique can be used in low back pain caused by degenerative disc disease or minor spondylolisthesis, but there are risks for fusion failure. Intravertebral bone graft is performed in painful osteoporotic or posttraumatic vertebral compression fractures (VCFs. Until now, no attempt has been made to apply intravertebral bone graft with AxiaLIF technique."nSo first, we hypothesize a novel method for tridimensional intravertebral bone graft with a special designed bone grafting instrument and describe it vividly. The special instrument would mainly consist of a hollow tube and a rod, the distal parts of them would be shape into 45o slope, so the direction of grafting would be decided by the slope. By rotating the tube we can deliver cancellous bone granules in one plane, but by retreating the tube we can perform tridimensional intravertebral bone graft. Second, intravertebral bone graft is supposed to be performed combined with AxiaLIF technique in order to create biologic vertebral reconstruction and raise fusion rate. We believe this is the first description of such a method, future clinical studies are needed to validate these hypotheses.

  1. MINIMALLY INVASIVE TRANSFORAMINAL LUMBAR INTERBODY FUSION IN DEGENERATIVE LUMBAR SPINE DISEASE

    Directory of Open Access Journals (Sweden)

    Pankaj

    2015-12-01

    Full Text Available OBJECTIVE To assess the clinical and radiological outcomes of Minimally Invasive Transforaminal Lumbar Interbody Fusion (MI-TLIF and to analyze the surgical outcome for degenerative lumbar spine disease. METHODS A multicenter retrospective analysis of 20 patients who underwent a MI-TLIF by image guidance from 1 January 2012 to April 2015. The study included 13 males and 7 females (Mean age 53 year. CT scan of operating area was done to evaluate the pedicle screw, cage placement and fusion at 6 months post operatively. Oswestry Disability Index (ODI scores and Visual Analogue Scale (VAS were recorded pre-operatively and at 6-month followup. RESULTS Eighteen (90% patients had evidence of fusion at 6 months post operatively with a mean improvement of 34 on the ODI score. Mean length of hospital stay was 4 days. The mean operative time was 170min. One patient developed transient nerve root pain in the postoperative period which was managed conservatively and one patient developed superficial wound infection. There was no case of CSF leak. CONCLUSION MI-TLIF is a safe and effective surgical procedure for management of degenerative lumbar spine disease.

  2. Transforaminal decompression and interbody fusion in the treatment of thoracolumbar fracture and dislocation with spinal cord injury.

    Directory of Open Access Journals (Sweden)

    Ai-Min Wu

    Full Text Available A retrospective clinical study.To evaluate the efficacy and safety of transforaminal decompression and interbody fusion in the treatment of thoracolumbar fracture and dislocation with spinal cord injury.Twenty-six spinal cord injured patients with thoracolumbar fracture and dislocation were treated by transforaminal decompression and interbody fusion. The operation time, intraoperative blood loss, and complications were recorded; the Cobb angle and compressive rate (CR of the anterior height of two adjacent vertebrae were measured; and the nerve injury was assessed according to sensory scores and motor scores of the American Spinal Injury Association (ASIA standards for neurological classification of spinal cord injury.The operative time was 250±57 min, and intraoperative blood loss was 440±168 ml. Cerebrospinal leakage was detected and repaired during the operation in two patients. A total of 24 of 26 patients were followed up for more than 2 years. ASIA sensory scores and motor scores were improved significantly at 3 months and 6 months after operation; the Cobb angle and CR of the anterior height of two adjacent vertebrae were corrected and showed a significant difference at post-operation; and the values were maintained at 3 months after operation and the last follow-up.We showed that transforaminal decompression together with interbody fusion is an alternative method to treat thoracolumbar fracture and dislocation.

  3. Lifestyle-Related Diseases Affect Surgical Outcomes after Posterior Lumbar Interbody Fusion.

    Science.gov (United States)

    Sakaura, Hironobu; Miwa, Toshitada; Yamashita, Tomoya; Kuroda, Yusuke; Ohwada, Tetsuo

    2016-02-01

    Study Design Retrospective study. Objective Hyperlipidemia (HL) and hypertension (HT) lead to systemic atherosclerosis. Not only atherosclerosis but also bone fragility and/or low bone mineral density result from diabetes mellitus (DM) and chronic kidney disease (CKD). The purpose of this study was to examine whether these lifestyle-related diseases affected surgical outcomes after posterior lumbar interbody fusion (PLIF). Methods The subjects comprised 122 consecutive patients who underwent single-level PLIF for degenerative lumbar spinal disorders. The clinical results were assessed using the Japanese Orthopaedic Association (JOA) score before surgery and at 2 years postoperatively. The fusion status was graded as union in situ, collapsed union, or nonunion at 2 years after surgery. The abdominal aorta calcification (AAC) score was assessed using preoperative lateral radiographs of the lumbar spine. Results HL did not significantly affect the JOA score recovery rate. On the other hand, HT and CKD (stage 3 to 4) had a significant adverse effect on the recovery rate. The recovery rate was also lower in the DM group than in the non-DM group, but the difference was not significant. The AAC score was negatively correlated with the JOA score recovery rate. The fusion status was not significantly affected by HL, HT, DM, or CKD; however, the AAC score was significantly higher in the collapsed union and nonunion group than in the union in situ group. Conclusions At 2 years after PLIF, the presence of HT, CKD, and AAC was associated with significantly worse clinical outcomes, and advanced AAC significantly affected fusion status. PMID:26835195

  4. Minimally invasive presacral approach for revision of an Axial Lumbar Interbody Fusion rod due to fall-related lumbosacral instability: a case report

    Directory of Open Access Journals (Sweden)

    Cohen Anders

    2011-09-01

    Full Text Available Abstract Introduction The purpose of this study was to describe procedural details of a minimally invasive presacral approach for revision of an L5-S1 Axial Lumbar Interbody Fusion rod. Case presentation A 70-year-old Caucasian man presented to our facility with marked thoracolumbar scoliosis, osteoarthritic changes characterized by high-grade osteophytes, and significant intervertebral disc collapse and calcification. Our patient required crutches during ambulation and reported intractable axial and radicular pain. Multi-level reconstruction of L1-4 was accomplished with extreme lateral interbody fusion, although focal lumbosacral symptoms persisted due to disc space collapse at L5-S1. Lumbosacral interbody distraction and stabilization was achieved four weeks later with the Axial Lumbar Interbody Fusion System (TranS1 Inc., Wilmington, NC, USA and rod implantation via an axial presacral approach. Despite symptom resolution following this procedure, our patient suffered a fall six weeks postoperatively with direct sacral impaction resulting in symptom recurrence and loss of L5-S1 distraction. Following seven months of unsuccessful conservative care, a revision of the Axial Lumbar Interbody Fusion rod was performed that utilized the same presacral approach and used a larger diameter implant. Minimal adhesions were encountered upon presacral re-entry. A precise operative trajectory to the base of the previously implanted rod was achieved using fluoroscopic guidance. Surgical removal of the implant was successful with minimal bone resection required. A larger diameter Axial Lumbar Interbody Fusion rod was then implanted and joint distraction was re-established. The radicular symptoms resolved following revision surgery and our patient was ambulating without assistance on post-operative day one. No adverse events were reported. Conclusions The Axial Lumbar Interbody Fusion distraction rod may be revised and replaced with a larger diameter rod using

  5. Posterior lumbar interbody fusion using nonresorbable poly-ether-ether-ketone versus resorbable poly-L-lactide-co-D,L-lactide fusion devices: a prospective, randomized study to assess fusion and clinical outcome

    NARCIS (Netherlands)

    Jiya, T.U.; Smit, T.H.; Deddens, J.; Mullender, M.G.

    2009-01-01

    STUDY DESIGN: A prospective randomized clinical study. OBJECTIVE.: To assess fusion, clinical outcome, and complications. SUMMARY OF BACKGROUND DATA: Resorbable poly-L- lactide-co-D,L-lactide (PLDLLA) cages intended to aid spinal interbody fusion have been introduced into clinical practice within th

  6. Reduction in adjacent-segment degeneration after multilevel posterior lumbar interbody fusion with proximal DIAM implantation.

    Science.gov (United States)

    Lu, Kang; Liliang, Po-Chou; Wang, Hao-Kuang; Liang, Cheng-Loong; Chen, Jui-Sheng; Chen, Tai-Been; Wang, Kuo-Wei; Chen, Han-Jung

    2015-08-01

    OBJECT Multilevel long-segment lumbar fusion poses a high risk for future development of adjacent-segment degeneration (ASD). Creating a dynamic transition zone with an interspinous process device (IPD) proximal to the fusion has recently been applied as a method to reduce the occurrence of ASD. The authors report their experience with the Device for Intervertebral Assisted Motion (DIAM) implanted proximal to multilevel posterior lumbar interbody fusion (PLIF) in reducing the development of proximal ASD. METHODS This retrospective study reviewed 91 cases involving patients who underwent 2-level (L4-S1), 3-level (L3-S1), or 4-level (L2-S1) PLIF. In Group A (42 cases), the patients received PLIF only, while in Group B (49 cases), an interspinous process device, a DIAM implant, was put at the adjacent level proximal to the PLIF construct. Bone resection at the uppermost segment of the PLIF was equally limited in the 2 groups, with preservation of the upper portion of the spinous process/lamina and the attached supraspinous ligament. Outcome measures included a visual analog scale (VAS) for low-back pain and leg pain and the Oswestry Disability Index (ODI) for functional impairment. Anteroposterior and lateral flexion/extension radiographs were used to evaluate the fusion status, presence and patterns of ASD, and mobility of the DIAM-implanted segment. RESULTS Solid interbody fusion without implant failure was observed in all cases. Radiographic ASD occurred in 20 (48%) of Group A cases and 3 (6%) of Group B cases (p Group A and 3 in Group B were symptomatic; of these patients, 3 in Group A and 1 in Group B underwent a second surgery for severe symptomatic ASD. At 24 months after surgery, Group A patients fared worse than Group B, showing higher mean VAS and ODI scores due to symptoms related to ASD. At the final follow-up evaluations, as reoperations had been performed to treat symptomatic ASD in some patients, significant differences no longer existed between the 2

  7. Effect of Elastic Modulus on Biomechanical Properties of Lumbar Interbody Fusion Cage

    Institute of Scientific and Technical Information of China (English)

    Yue Zhu; Fusheng Li; Shujun Li; Yulin Hao; Rui Yang

    2009-01-01

    This work focuses on the influence of elastic modulus on biomechanical properties of lumbar interbody fusion cages by selecting two titanium alloys with different elastic modulus.They were made by a new β type alloy with chemical composition of Ti-24Nb-4Zr-7.6Sn having low Young's modulus ~50 GPa and by a conventional biomedical alloy Ti-6Al-4V having Young's modulus ~110 GPa.The results showed that the designed cages with low modulus (LMC) and high modulus (HMC) can keep identical compression load ~9.8 kN and endure fatigue cycles higher than 5× 106 without functional or mechanical failure under 2.0 kN axial compression.The anti-subsidence ability of both group cages were examined by axial compression of thoracic spine specimens (T9~T10) dissected freshly from the calf with averaged age of 6 months.The results showed that the LMC has better anti-subsidence ability than the HMC (p<0.05).The above results suggest that the cage with low elastic modulus has great potential for clinical applications.

  8. Total 3D Airo® Navigation for Minimally Invasive Transforaminal Lumbar Interbody Fusion

    Science.gov (United States)

    Lian, Xiaofeng; Berlin, Connor; Moriguchi, Yu; Zhang, Qiwei; Härtl, Roger

    2016-01-01

    Introduction. A new generation of iCT scanner, Airo®, has been introduced. The purpose of this study is to describe how Airo facilitates minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF). Method. We used the latest generation of portable iCT in all cases without the assistance of K-wires. We recorded the operation time, number of scans, and pedicle screw accuracy. Results. From January 2015 to December 2015, 33 consecutive patients consisting of 17 men and 16 women underwent single-level or two-level MIS-TLIF operations in our institution. The ages ranged from 23 years to 86 years (mean, 66.6 years). We treated all the cases in MIS fashion. In four cases, a tubular laminectomy at L1/2 was performed at the same time. The average operation time was 192.8 minutes and average time of placement per screw was 2.6 minutes. No additional fluoroscopy was used. Our screw accuracy rate was 98.6%. No complications were encountered. Conclusions. Airo iCT MIS-TLIF can be used for initial planning of the skin incision, precise screw, and cage placement, without the need for fluoroscopy. “Total navigation” (complete intraoperative 3D navigation without fluoroscopy) can be achieved by combining Airo navigation with navigated guide tubes for screw placement. PMID:27529069

  9. Total 3D Airo® Navigation for Minimally Invasive Transforaminal Lumbar Interbody Fusion.

    Science.gov (United States)

    Lian, Xiaofeng; Navarro-Ramirez, Rodrigo; Berlin, Connor; Jada, Ajit; Moriguchi, Yu; Zhang, Qiwei; Härtl, Roger

    2016-01-01

    Introduction. A new generation of iCT scanner, Airo®, has been introduced. The purpose of this study is to describe how Airo facilitates minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF). Method. We used the latest generation of portable iCT in all cases without the assistance of K-wires. We recorded the operation time, number of scans, and pedicle screw accuracy. Results. From January 2015 to December 2015, 33 consecutive patients consisting of 17 men and 16 women underwent single-level or two-level MIS-TLIF operations in our institution. The ages ranged from 23 years to 86 years (mean, 66.6 years). We treated all the cases in MIS fashion. In four cases, a tubular laminectomy at L1/2 was performed at the same time. The average operation time was 192.8 minutes and average time of placement per screw was 2.6 minutes. No additional fluoroscopy was used. Our screw accuracy rate was 98.6%. No complications were encountered. Conclusions. Airo iCT MIS-TLIF can be used for initial planning of the skin incision, precise screw, and cage placement, without the need for fluoroscopy. "Total navigation" (complete intraoperative 3D navigation without fluoroscopy) can be achieved by combining Airo navigation with navigated guide tubes for screw placement. PMID:27529069

  10. Total 3D Airo® Navigation for Minimally Invasive Transforaminal Lumbar Interbody Fusion

    Directory of Open Access Journals (Sweden)

    Xiaofeng Lian

    2016-01-01

    Full Text Available Introduction. A new generation of iCT scanner, Airo®, has been introduced. The purpose of this study is to describe how Airo facilitates minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF. Method. We used the latest generation of portable iCT in all cases without the assistance of K-wires. We recorded the operation time, number of scans, and pedicle screw accuracy. Results. From January 2015 to December 2015, 33 consecutive patients consisting of 17 men and 16 women underwent single-level or two-level MIS-TLIF operations in our institution. The ages ranged from 23 years to 86 years (mean, 66.6 years. We treated all the cases in MIS fashion. In four cases, a tubular laminectomy at L1/2 was performed at the same time. The average operation time was 192.8 minutes and average time of placement per screw was 2.6 minutes. No additional fluoroscopy was used. Our screw accuracy rate was 98.6%. No complications were encountered. Conclusions. Airo iCT MIS-TLIF can be used for initial planning of the skin incision, precise screw, and cage placement, without the need for fluoroscopy. “Total navigation” (complete intraoperative 3D navigation without fluoroscopy can be achieved by combining Airo navigation with navigated guide tubes for screw placement.

  11. Magnetic resonance imaging analysis of surgical trans-sacral axial L5/S1 interbody fusion

    Institute of Scientific and Technical Information of China (English)

    YAN Ning; HE Shi-sheng; ZHANG Hai-long; GU Guang-fei; LIU Bi-feng; LIU Yan-bin; ZHANG Li-guo; GU Xin; DING Yue; GUO Cheng-bin

    2011-01-01

    Background Trans-sacral axial L5/S1 interbody fusion (AxiaLIF), a novel surgical procedure, recently adopted in clinical practice, has excellent clinical outcomes. However, there is inadequate data on the feasibility of the approach in all adult patients and the optimal surgical approach is currently unclear; therefore, further studies are required. In order to enhance the surgical approach for AxiaLIF, prospective anatomical imaging optimization is necessary. The objective of this study was to investigate the ability of magnetic resonance imaging (MRI) to achieve an optimal procedural setting.Methods The subjects (n=40) underwent lumbosacral MRI examination. The median sagittal MRI images were analyzed and four measurement markers were defined as follows: the center of the L5/S1 disc (A), the anterior margin of the S1/2 disc space (B), the sacrococcygeal junction (C), and the coccygeal tip (D). The measurement markers were connected to each other to produce five lines (AB, AC, AD, BC, and BD), as reference lines for surgical approaches. The distance between each reference line and the anterior and posterior margins of the L5 and S1 vertebral bodies was measured to determine the safety of the respective approaches.Results In all patients, Lines AB and AC satisfied the imaging safety criteria. Line AB would result in a significant deviation from the median and was determined to be unsuitable for AxiaLIF. Line AD satisfied the imaging safety criteria in 39 patients. However, the anal proximity of the puncture point proved to be limiting. For lines BC and BD, the imaging safety criteria were satisfied in 70% and 45% of patients, respectively.Conclusions The AxiaLIF procedure is a safe technique for insertion of fusion implants in all subjects. Line AC is a favorable reference line for surgical approach and safe for all subjects, while line BC is not suitable for all subjects.

  12. Evaluation of a novel tool for bone graft delivery in minimally invasive transforaminal lumbar interbody fusion

    Directory of Open Access Journals (Sweden)

    Kleiner JB

    2016-05-01

    Full Text Available Jeffrey B Kleiner, Hannah M Kleiner, E John Grimberg Jr, Stefanie J Throlson The Spine Center of Innovation, The Medical Center of Aurora, Aurora, CO, USA Study design: Disk material removed (DMR during L4-5 and L5-S1 transforaminal lumbar interbody fusion (T-LIF surgery was compared to the corresponding bone graft (BG volumes inserted at the time of fusion. A novel BG delivery tool (BGDT was used to apply the BG. In order to establish the percentage of DMR during T-LIF, it was compared to DMR during anterior diskectomy (AD. This study was performed prospectively. Summary of background data: Minimal information is available as to the volume of DMR during a T-LIF procedure, and the relationship between DMR and BG delivered is unknown. BG insertion has been empiric and technically challenging. Since the volume of BG applied to the prepared disk space likely impacts the probability of arthrodesis, an investigation is justified. Methods: A total of 65 patients with pathology at L4-5 and/or L5-S1 necessitating fusion were treated with a minimally invasive T-LIF procedure. DMR was volumetrically measured during disk space preparation. BG material consisting of local autograft, BG extender, and bone marrow aspirate were mixed to form a slurry. BG slurry was injected into the disk space using a novel BGDT and measured volumetrically. An additional 29 patients who were treated with L5-S1 AD were compared to L5-S1 T-LIF DMR to determine the percent of T-LIF DMR relative to AD. Results: DMR volumes averaged 3.6±2.2 mL. This represented 34% of the disk space relative to AD. The amount of BG delivered to the disk spaces was 9.3±3.2 mL, which is 2.6±2.2 times the amount of DMR. The BGDT allowed uncomplicated filling of the disk space in <1 minute. Conclusion: The volume of DMR during T-LIF allows for a predictable volume of BG delivery. The BGDT allowed complete filling of the entire prepared disk space. The T-LIF diskectomy debrides 34% of the disk

  13. Minimally invasive lumbar interbody fusion via MAST Quadrant retractor versus open surgery: a prospective randomized clinical trial

    Institute of Scientific and Technical Information of China (English)

    WANG Hong-li; L(U) Fei-zhou; JIANG Jian-yuan; MA Xin; XIA Xin-lei; WANG Li-xun

    2011-01-01

    Background In recent years,a variety of minimally invasive lumbar surgery techniques have achieved desirable efficacy,but some dispute remains regarding the advantages over open surgery.This study aimed to compare minimally invasive lumbar interbody fusion via MAST Quadrant retractor with open surgery in terms of perioperative factors,postoperative back muscle function,and 24-month postoperative follow-up results.Methods From September 2006 to June 2008,patients with single-level degenerative lumbar spine disease who were not responsive to conservative treatment were enrolled in this study.Patients were randomized to undergo either minimally invasive surgery (MIS,transforaminal lumbar interbody fusion via MAST Quadrant retractor,41 cases) or open surgery (improved transforaminal lumbar interbody fusion,38 cases).Results The MIS group had longer intraoperative fluoroscopy time than the open surgery group,and the open surgery group had significantly increased postoperative drainage volume and significantly prolonged postoperative recovery time compared with the MIS group (P <0.05 for all).MRI scanning showed that the T2 relaxation time in the multifidus muscle was significantly shorter in the MIS group than in the open surgery group at 3 months after surgery (P <0.01).Surface electromyography of the sacrospinalis muscle showed that the average discharge amplitude and frequency were significantly higher in the MIS group than in the open surgery group (P <0.01).The Oswestry disability index and visual analog scale scores were better at 3,6,12 and 24 months postoperatively than preoperatively in both groups.Both groups of patients met the imaging convergence criteria at the last follow-up.Conclusions MIS can effectively reduce sacrospinalis muscle injury compared with open surgery,which is conducive to early functional recovery.In the short term,MIS is superior to open surgery,but in the long term there is no significant difference between the two procedures.

  14. Adjacent Segment Pathology after Anterior Cervical Fusion.

    Science.gov (United States)

    Chung, Jae Yoon; Park, Jong-Beom; Seo, Hyoung-Yeon; Kim, Sung Kyu

    2016-06-01

    Anterior cervical fusion has become a standard of care for numerous pathologic conditions of the cervical spine. However, subsequent development of clinically significant disc disease at levels adjacent to fused discs is a serious long-term complication of this procedure. As more patients live longer after surgery, it is foreseeable that adjacent segment pathology (ASP) will develop in increasing numbers of patients. Also, ASP has been studied more intensively with the recent popularity of motion preservation technologies like total disc arthroplasty. The true nature and scope of ASP remains poorly understood. The etiology of ASP is most likely multifactorial. Various factors including altered biomechanical stresses, surgical disruption of soft tissue and the natural history of cervical disc disease contribute to the development of ASP. General factors associated with disc degeneration including gender, age, smoking and sports may play a role in the development of ASP. Postoperative sagittal alignment and type of surgery are also considered potential causes of ASP. Therefore, a spine surgeon must be particularly careful to avoid unnecessary disruption of the musculoligamentous structures, reduced risk of direct injury to the disc during dissection and maintain a safe margin between the plate edge and adjacent vertebrae during anterior cervical fusion.

  15. Mast Quadrant-assisted Minimally Invasive Modified Transforaminal Lumbar Interbody Fusion: Single Incision Versus Double Incision

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    Xin-Lei Xia

    2015-01-01

    Full Text Available Background: The concept of minimally invasive techniques is to make every effort to reduce tissue damage. Certainly, reducing skin incision is an important part of these techniques. This study aimed to investigate the clinical feasibility of Mast Quadrant-assisted modified transforaminal lumbar interbody fusion (TLIF with a small single posterior median incision. Methods: During the period of March 2011 to March 2012, 34 patients with single-segment degenerative lumbar disease underwent the minimally invasive modified TLIF assisted by Mast Quadrant with a small single posterior median incision (single incision group. The cases in this group were compared to 37 patients with single-segment degenerative lumbar disease in the double incision group. The perioperative conditions of patients in these two groups were statistically analyzed and compared. The Oswestry Disability Index (ODI scores, Visual Analog Scale (VAS scores, and sacrospinalis muscle damage evaluation indicators before operation and 3, 12 months postoperation were compared. Results: A total of 31 and 35 cases in the single incision and double incision groups, respectively, completed at least 12 months of systemic follow-up. The differences in perioperative conditions between the two groups were not statistically significant. The incision length of the single incision group was significantly shorter than that of the double incision group (P < 0.01. The ODI and VAS scores of patients in both groups improved significantly at 3 and 12 months postoperation. However, these two indicators at 3 and 12 months postoperation and the sacrospinalis muscle damage evaluation indicators at 3 months postoperation did not differ significantly between the two groups (P ≥ 0.05. Conclusions: Mast Quadrant-assisted modified TLIF with a small single posterior median incision has excellent clinical feasibility compared to minimally invasive TLIF with a double paramedian incision.

  16. Comparison of the Dynesys Dynamic Stabilization System and Posterior Lumbar Interbody Fusion for Lumbar Degenerative Disease.

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    Yang Zhang

    Full Text Available There have been few studies comparing the clinical and radiographic outcomes between the Dynesys dynamic stabilization system and posterior lumbar interbody fusion (PLIF. The objective of this study is to compare the clinical and radiographic outcomes of Dynesys and PLIF for lumbar degenerative disease.Of 96 patients with lumbar degenerative disease included in this retrospectively analysis, 46 were treated with the Dynesys system and 50 underwent PLIF from July 2008 to March 2011. Clinical and radiographic outcomes were evaluated. We also evaluated the occurrence of radiographic and symptomatic adjacent segment degeneration (ASD.The mean follow-up time in the Dynesys group was 53.6 ± 5.3 months, while that in the PLIF group was 55.2 ± 6.8 months. At the final follow-up, the Oswestry disability index and visual analogue scale score were significantly improved in both groups. The range of motion (ROM of stabilized segments in Dynesys group decreased from 7.1 ± 2.2° to 4.9 ± 2.2° (P < 0.05, while that of in PLIF group decreased from 7.3 ± 2.3° to 0° (P < 0.05. The ROM of the upper segments increased significantly in both groups at the final follow-up, the ROM was higher in the PLIF group. There were significantly more radiographic ASDs in the PLIF group than in the Dynesys group. The incidence of complications was comparable between groups.Both Dynesys and PLIF can improve the clinical outcomes for lumbar degenerative disease. Compared to PLIF, Dynesys stabilization partially preserves the ROM of the stabilized segments, limits hypermobility in the upper adjacent segment, and may prevent the occurrence of ASD.

  17. Mast Quadrant-assisted Minimally Invasive Modified Transforaminal Lumbar Interbody Fusion: Single Incision Versus Double Incision

    Institute of Scientific and Technical Information of China (English)

    Xin-Lei Xia; Hong-Li Wang; Fei-Zhou Lyu; Li-Xun Wang; Xiao-Sheng Ma; Jian-Yuan Jiang

    2015-01-01

    Background:The concept of minimally invasive techniques is to make every effort to reduce tissue damage.Certainly,reducing skin incision is an important part of these techniques.This study aimed to investigate the clinical feasibility of Mast Quadrant-assisted modified transforaminal lumbar interbody fusion (TLIF) with a small single posterior median incision.Methods:During the period of March 2011 to March 2012,34 patients with single-segment degenerative lumbar disease underwent the minimally invasive modified TLIF assisted by Mast Quadrant with a small single posterior median incision (single incision group).The cases in this group were compared to 37 patients with single-segment degenerative lumbar disease in the double incision group.The perioperative conditions of patients in these two groups were statistically analyzed and compared.The Oswestry Disability Index (ODI) scores,Visual Analog Scale (VAS) scores,and sacrospinalis muscle damage evaluation indicators before operation and 3,12 months postoperation were compared.Results:A total of 31 and 35 cases in the single incision and double incision groups,respectively,completed at least 12 months of systemic follow-up.The differences in perioperative conditions between the two groups were not statistically significant.The incision length of the single incision group was significantly shorter than that of the double incision group (P < 0.01).The ODI and VAS scores of patients in both groups improved significantly at 3 and 12 months postoperation.However,these two indicators at 3 and 12 months postoperation and the sacrospinalis muscle damage evaluation indicators at 3 months postoperation did not differ significantly between the two groups (P ≥ 0.05).Conclusions:Mast Quadrant-assisted modified TLIF with a small single posterior median incision has excellent clinical feasibility compared to minimally invasive TLIF with a double paramedian incision.

  18. Effect of Psychological Status on Outcome of Posterior Lumbar Interbody Fusion Surgery

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    Lakkol, Sandesh; Budithi, Chakra; Bhatia, Chandra; Krishna, Manoj

    2012-01-01

    Study Design Prospective longitudinal study. Purpose To determine if preoperative psychological status affects outcome in spinal surgery. Overview of Literature Low back pain is known to have a psychosomatic component. Increased bodily awareness (somatization) and depressive symptoms are two factors that may affect outcome. It is possible to measure these components using questionnaires. Methods Patients who underwent posterior interbody fusion (PLIF) surgery were assessed preoperatively and at follow-up using a self-administered questionnaire. The visual analogue scale (VAS) for back and leg pain severity and the Oswestry Disability Index (ODI) were used as outcome measures. The psychological status of patients was classified into one of four groups using the Distress and Risk Assessment Method (DRAM); normal, at-risk, depressed somatic and distressed depressive. Results Preoperative DRAM scores showed 14 had no psychological disturbance (normal), 39 were at-risk, 11 distressed somatic, and 10 distressed depressive. There was no significant difference between the 4 groups in the mean preoperative ODI (analysis of variance, p = 0.426). There was a statistically and clinically significant improvement in the ODI after surgery for all but distressed somatic patients (9.8; range, -5.2 to 24.8; p = 0.177). VAS scores for all groups apart from the distressed somatic showed a statistically and clinically significant improvement. Our results show that preoperative psychological state affects outcome in PLIF surgery. Conclusions Patients who were classified as distressed somatic preoperatively had a less favorable outcome compared to other groups. This group of patients may benefit from formal psychological assessment before undergoing PLIF surgery. PMID:22977697

  19. The concave versus convex approach for minimally invasive lateral lumbar interbody fusion for thoracolumbar degenerative scoliosis.

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    Scheer, Justin K; Khanna, Ryan; Lopez, Alejandro J; Fessler, Richard G; Koski, Tyler R; Smith, Zachary A; Dahdaleh, Nader S

    2015-10-01

    We retrospectively reviewed patient charts to compare the approach-related (convex versus concave) neurological complications and magnitude of correction in patients undergoing lateral lumbar interbody fusion (LLIF). It is yet to be quantitatively determined if correction of adult degenerative scoliosis from either side of the curve apex using a LLIF results in a reduction in complications and/or improved corrective ability. The inclusion criteria for this study were patients who underwent a LLIF for adult degenerative thoracolumbar scoliosis and had the LLIF prior to any other supplemental procedures. Patients were grouped based on the approach toward the curve apex concavity (CAVE) or the convexity (VEX). Standard coronal and sagittal radiographic measurements were made. Neurological complications and reoperation indications were also recorded. We included 32 patients for review (CAVE: 17; VEX: 15) with a mean age of 65.5 years±a standard deviation of 10.2, and mean follow-up of 17.0 months±15.7. There were eight postoperative neurological complications in eight patients (25.0%), and seven reoperations for six patients (18.8%; CAVE: 4/17 [23.5%]; VEX: 2/15 [13.3%]). The CAVE group had 6/17 neurological complications (35.3%; four ipsilateral and two contralateral to approach side) and VEX had 2/15 (13.3%; one ipsilateral and one bilateral to approach side; p>0.05). All patients significantly improved in the mean regional and segmental Cobb angles (p0.05). There were no significant differences between the groups for any of the radiographic parameters measured (p>0.05). Approaching the curve apex from either the concave or convex side resulted in significant improvements. The concave approach was associated with more postoperative neurological complications.

  20. Use of 3D CT-based navigation in minimally invasive lateral lumbar interbody fusion.

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    Joseph, Jacob R; Smith, Brandon W; Patel, Rakesh D; Park, Paul

    2016-09-01

    OBJECTIVE Lateral lumbar interbody fusion (LLIF) is an increasingly popular technique used to treat degenerative lumbar disease. The technique of using an intraoperative cone-beam CT (iCBCT) and an image-guided navigation system (IGNS) for LLIF cage placement has been previously described. However, other than a small feasibility study, there has been no clinical study evaluating its accuracy or safety. Therefore, the purpose of this study was to evaluate the accuracy and safety of image-guided spinal navigation in LLIF. METHODS An analysis of a prospectively acquired database was performed. Thirty-one consecutive patients were identified. Accuracy was initially determined by comparison of the planned trajectory of the IGNS with post-cage placement intraoperative fluoroscopy. Accuracy was subsequently confirmed by postprocedural CT and/or radiography. Cage placement was graded based on a previously described system separating the disc space into quarters. RESULTS The mean patient age was 63.9 years. A total of 66 spinal levels were treated, with a mean of 2.1 levels (range 1-4) treated per patient. Cage placement was noted to be accurate using IGNS in each case, as confirmed with intraoperative fluoroscopy and postoperative imaging. Sixty-four (97%) cages were placed within Quarters 1 to 2 or 2 to 3, indicating placement of the cage in the anterior or middle portions of the disc space. There were no instances of misguidance by IGNS. There was 1 significant approach-related complication (psoas muscle abscess) that required intervention, and 8 patients with transient, mild thigh paresthesias or weakness. CONCLUSIONS LLIF can be safely and accurately performed utilizing iCBCT and IGNS. Accuracy is acceptable for multilevel procedures. PMID:27104283

  1. Minimally invasive transforaminal lumbar interbody fusion aided with computer-assisted spinal navigation system combined with electromyography monitoring

    Institute of Scientific and Technical Information of China (English)

    LUO Wei; ZHANG Fan; LIU Tie; DU Xing-li; CHEN An-ming; LI Feng

    2012-01-01

    Background Minimally invasive techniques are gaining wide-spread application in lumbar fusion surgery,because they may have advantage over conventional open surgery in approach-related morbidity.This research was aimed to evaluate the safety and accuracy of the techniques of minimally invasive transforaminal lumbar interbody fusion by using a computer-assisted spinal navigation system combined with electromyography monitoring.Methods Sixteen patients underwent minimally invasive transforaminal lumbar interbody fusion.A computer-assisted spinal navigation system and electromyography were used for guiding pedicle screw placement.The operative duration,blood loss,complications,and fluoroscopic time were recorded.Clinical outcome was assessed by Visual Analog Scale and Oswestry Disability Index.Radiographic images were obtained to evaluate the accuracy of pedicle screw placement and fusion rates.Results The Visual Analog Scale and Oswestry Disability Index scores were vastly improved postoperatively.A total of 64 pedicle screws were implanted and three were regarded as misplacement by post-operative CT scan.Three screw trajectories were adjusted according to intra-operative stimulus-evoked electromyography monitoring.The average fluoroscopy time in each patient was 31.8 seconds,which equals to 7.9 seconds per pedicle screw.No patients had instrument related neurological complications,infection,implant failure or revision.Successful fusion was found in all patients.Conclusions The combination of navigation system and real-time electromyography monitoring can make the minimally invasive operation more safe and accurate while decreasing radiation exposure time of the medical staff and patient and minimizing the chance and the degree of the pedicle screw misplacement.

  2. Artrodese cervical anterior em três e quatro níveis com dispositivo intersomático não associado à placa cervical Artrodesis cervical anterior en tres y cuatro niveles con dispositivo intersomático no asociado a placa cervical Anterior cervical arthrodesis for three and four levels using stand-alone interbody cages without cervical plates

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    Marcel Luiz Benato

    2009-06-01

    en tercer y cuarto niveles; dolor axial y/o irradiada; con mínimo seis meses de postoperatorio. El criterio de exclusión fue la presencia de inestabilidad cervical traumática. Fueron evaluadas las tasas de consolidación, la presencia de síntomas, la tasa de complicaciones y la posición de los dispositivos intersomáticos (subsidente después de seis meses. RESULTADOS: todos los pacientes obtuvieron consolidación en tres meses, sin embargo, dos pacientes presentaron el fenómeno de subsidente, o sea, migración con consolidación en cifosis, sin alterar los resultados clínicos y la consolidación de la artrodesis a los seis meses de postoperatorio. Los pacientes presentaron mejoría del dolor preoperatorio y solo tres (15% presentaron dolor residual. No hubo complicaciones mayores. El tiempo de hospitalización fue de dos días. No fue utilizada inmovilización rígida en el postoperatorio. CONCLUSIÓN: fue obtenida consolidación con esta técnica en todos los casos. La técnica se mostró segura y promovió buenos resultados radiológicos y clínicos.evaluate the rates of fusion of the anterior cervical discectomy and arthrodesis for three and four levels using interbody cages (stand-alone without cervical plates six months after post-operative. METHODS: from November 2005 to July 2008, 20 patients were treated as proposed. The inclusion criteria were: cervical degenerative disease of three and four levels; axial and/or irradiated pain at least six months of follow-up. The exclusion criteria were: cervical traumatic instability. The fusion rate, clinical symptoms, rate of complications and the implant position were evaluated six months after post-operative. RESULTS: results were favorable in 100% of the patients, with residual pain in two cases. Fusion was found in 100% of the patients, except for two cases with minimum subsidence and fusion in a slight kyphotic position. There were not significant complications. The discharge of the hospital was performed

  3. Anterior cervical discectomy and fusion for noncontiguous cervical spondylotic myelopathy

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    Sun Qizhi

    2016-01-01

    Full Text Available Background: Noncontiguous cervical spondylotic myelopathy (CSM is a special degenerative disease because of the intermediate normal level or levels between supra and infraabnormal levels. Some controversy exists over the optimal procedure for two noncontiguous levels of CSM. The study was to evaluate the outcomes of the anterior cervical discectomy and fusion (ACDF with zero-profile devices for two noncontiguous levels of CSM. Materials and Methods: 17 consecutive patients with two noncontiguous levels of CSM operated between December 2009 and August 2012 were included in the study. There were 12 men and 5 women with a mean age of 60.7 years (range 45-75 years. Involved disc levels were C3/4 and C5/6 in 11 patients and C4/5 and C6/7 in six patients. Preoperative plain radiographs, computed tomography (CT with 3-D reconstruction and magnetic resonance imaging (MRI of the cervical spine were taken in all patients. All radiographs were independently evaluated by 2 spine surgeons and 1 radiologist. The outcomes were assessed by the average operative time, blood loss, Japanese Orthopedic Association (JOA score, improvement rate, neck dysfunction index (NDI, swallowing quality of life (SWAL-QOL score, the cervical lordosis and complications. Results: The mean followup was 48.59 months (range 24-56 months. The average operative time and blood loss was 105.29 min and 136.47 ml, respectively. The preoperative JOA score was 8.35, which significantly increased to 13.7 at the final followup ( P 0.05. Cerebrospinal fluid leak, dysphagia and radiological adjacent segment degeneration occurred in one patient, respectively. Conclusion: The ACDF with zero-profile devices is generally effective and safe in treating two noncontiguous levels of CSM.

  4. Single-stage Anterior and Posterior Fusion Surgery for Correction of Cervical Kyphotic Deformity Using Intervertebral Cages and Cervical Lateral Mass Screws: Postoperative Changes in Total Spine Sagittal Alignment in Three Cases with a Minimum Follow-up of Five Years.

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    Ogihara, Satoshi; Kunogi, Junichi

    2015-01-01

    The surgical treatment of cervical kyphotic deformity remains challenging. As a surgical method that is safer and avoids major complications, the authors present a procedure of single-stage anterior and posterior fusion to correct cervical kyphosis using anterior interbody fusion cages without plating, as illustrated by three consecutive cases. Case 1 was a 78-year-old woman who presented with a dropped head caused by degeneration of her cervical spine. Case 2 was a 54-year-old woman with athetoid cerebral palsy. She presented with cervical myelopathy and cervical kyphosis. Case 3 was a 71-year-old woman with cervical kyphotic deformity following a laminectomy. All three patients underwent anterior release and interbody fusion with cages and posterior fusion with cervical lateral mass screw (LMS) fixation. Postoperative radiographs showed that correction of kyphosis was 39° in case 1, 43° in case 2, and 39° in case 3. In all three cases, improvement of symptoms was established without major perioperative complications, solid fusion was achieved, and no loss of correction was observed at a minimum follow-up of 61 months. We also report that preoperative total spine sagittal malalignment was improved after corrective surgery for cervical kyphosis and was maintained at the latest follow-up in all three cases. The combination of anterior fusion cages and LMS is considered a safe and effective procedure in cases of severe cervical kyphotic deformity. Preoperative total spine sagittal malalignment improved, accompanied by correction of cervical kyphosis, and was maintained at last follow-up in all three cases. PMID:26119893

  5. [Three-dimensional Finite Element Analysis of Biomechanical Effect of Rigid Fixation and Elastic Fixation on Lumbar Interbody Fusion].

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    Wei, Jiangbo; Song, Yueming; Liu, Limin; Zhou, Chunguan; Yang, Xi

    2015-04-01

    This study was aimed to compare the mechanical characteristics under different physiological load conditions with three-dimensional finite element model of rigid fixation and elastic fixation in the lumbar. We observed the stress distribution characteristics of a sample of healthy male volunteer modeling under vertical, flexion and extension torque situation. The outcomes showed that there existed 4-6 times pressure on the connecting rod of rigid fixation compared with the elastic fixations under different loads, and the stress peak and area of force on elastic fixation were much higher than that of the rigid fixations. The elastic fixation has more biomechanical advantages than rigid fixation in promoting interbody lumbar fusion after surgery. PMID:26211247

  6. Clinico-radiological profile of indirect neural decompression using cage or auto graft as interbody construct in posterior lumbar interbody fusion in spondylolisthesis: Which is better?

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    Q R Abdul

    2011-01-01

    Full Text Available Study design: A prospective clinical study of posterior lumbar interbody fusion in grade I and II degenerative spondylolisthesis was conducted between Mar 2007 and Aug 2008. Purpose: The objective was to assess the clinicoradiological profile of structural v/s nonstructural graft on intervertebral disc height and its consequences on the low back pain (LBP assessed by Visual analog score (VAS score and oswestry disability index (ODI . This study involved 28 patients. Inclusion criteria: Age of 30-70 years, symptomatic patient with disturbed Activities of daily living (ADL, single-level L4/L5 or L5/S1 grade I or grade II degenerative spondylolisthesis. Exclusion criteria: Patients with osteoporosis, recent spondylodiscitis, subchondral sclerosis, visual and cognitive impairment and all other types of spondylolisthesis. All the patients underwent short-segment posterior fixation using CD2 or M8 instrumentation, laminectomy discectomy, reduction and distraction of the involved vertebral space. In 53.5% (n = 15 of the patients, snugly fitted local bone chips were used while in 46.4% (n = 13 of the patients, cage was used. Among the cage group, titanium cage was used in nine (32.1% and PEEK cages were used in four (14.2% patients. In one patient, a unilateral PEEK cage was used. The mean follow-up period was 24 months. Among the 28 patients, 67.8% (n = 19 were females and 32.14% (n = 9 were males. 68.24% (n = 18 had L4/L5 and 35.71% (n = 10 had L5/S1 spondylolisthesis. 39.28% (n = 11 were of grade I and 60.71% (n = 17 were of grade II spondylolisthesis. Conclusions: There was a statistically significant correlation (P < 0.012 and P < 0.027 between the change in disc height achieved and the improvement in VAS score in both the graft group and the cage group. The increment in disc height and VAS score was significantly better in the cage group (2 mm ± SD vis-a-vis 7.2 [88%] than the graft group (1.2 mm ± SD vis-a-vis 5 [62 %].

  7. Minimally Invasive Transforaminal Lumbar Interbody Fusion at L5-S1 through a Unilateral Approach: Technical Feasibility and Outcomes

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    Choi, Won-Suh; Kim, Jin-Sung; Ryu, Kyeong-Sik; Hur, Jung-Woo; Seong, Ji-Hoon

    2016-01-01

    Background. Minimally invasive spinal transforaminal lumbar interbody fusion (MIS-TLIF) at L5-S1 is technically more demanding than it is at other levels because of the anatomical and biomechanical traits. Objective. To determine the clinical and radiological outcomes of MIS-TLIF for treatment of single-level spinal stenosis low-grade isthmic or degenerative spondylolisthesis at L5-S1. Methods. Radiological data and electronic medical records of patients who underwent MIS-TLIF between May 2012 and December 2014 were reviewed. Fusion rate, cage position, disc height (DH), disc angle (DA), disc slope angle, segmental lordotic angle (SLA), lumbar lordotic angle (LLA), and pelvic parameters were assessed. For functional assessment, the visual analogue scale (VAS), Oswestry disability index (ODI), and patient satisfaction rate (PSR) were utilized. Results. A total of 21 levels in 21 patients were studied. DH, DA, SLA, and LLA had increased from their preoperative measures at the final follow-up. Fusion rate was 86.7% (18/21) at 12 months' follow-up. The most common cage position was anteromedial (15/21). The mean VAS scores for back and leg pain mean ODI scores improved significantly at the final follow-up. PSR was 88%. Cage subsidence was observed in 33.3% (7/21). Conclusions. The clinical and radiologic outcomes after MIS-TLIF at L5-S1 in patients with spinal stenosis or spondylolisthesis are generally favorable. PMID:27433472

  8. Application and development of transforaminal lumbar interbody fusion%经椎间孔腰椎椎体间融合术的应用与发展

    Institute of Scientific and Technical Information of China (English)

    李华; 王辉; 丁文元

    2015-01-01

    Lumbar fusion has become a major surgical method in the treatment of lumbar degenerative diseases. Transforaminal lumbar interbody fusion ( TLIF ) has a series of advantages such as less damage to lumbar structure, less nerve injuries and less postoperative complications. With the constant increase of lumbar degenerative diseases, TLIF has been rapidly developed in recent years. With the development of surgery, minimally invasive technique has been used in TLIF. Minimally invasive-TLIF ( MI-TLIF ) has become one of the research hotspots in spinal surgery. The development process, technical features, biomechanical advantages, internal ifxation methods and fusion materials of TLIF and MI-TLIF are reviewed in this paper.

  9. Endoscopic minimally invasive transforaminal interbody fusion without general anesthesia: initial clinical experience with 1-year follow-up.

    Science.gov (United States)

    Wang, Michael Y; Grossman, Jay

    2016-02-01

    OBJECTIVE One of the principal goals of minimally invasive surgery has been to speed postoperative recovery. In this case series, the authors used an endoscopic technique for interbody fusion combined with percutaneous screw fixation to obviate the need for general anesthesia. METHODS The first 10 consecutive patients treated with a minimum of 1 year's follow-up were included in this series. The patients were all treated using endoscopic access through Kambin's triangle to allow for neural decompression, discectomy, endplate preparation, and interbody fusion. This was followed by percutaneous pedicle screw and connecting rod placement using liposomal bupivacaine for long-acting analgesia. No narcotics or regional anesthetics were used during surgery. RESULTS All patients underwent the procedure successfully without conversion to open surgery. The patients' average age was 62.2 ± 9.0 years (range 52-78 years). All patients had severe disc height collapse, and 60% had a Grade I spondylolisthesis. The mean operative time was 113.5 ± 6.3 minutes (range 105-120 minutes), and blood loss was 65 ± 38 ml (range 30-190 ml). The mean length of hospital stay was 1.4 ± 1.3 nights. There were no intraoperative or postoperative complications. Comparison of preoperative and final clinical metrics demonstrated that the Oswestry Disability Index improved from 42 ± 11.8 to 13.3 ± 15.1; the 36-Item Short Form Health Survey (SF-36) Physical Component Summary improved from 47.6 ± 3.8 to 49.7 ± 5.4; the SF-36 Mental Component Summary decreased from 47 ± 3.9 to 46.7 ± 3.4; and the EQ-5D improved from 10.7 ± 9.5 to 14.2 ± 1.6. There were no cases of nonunion identified radiographically on follow-up imaging. CONCLUSIONS Endoscopic fusion under conscious sedation may represent a feasible alternative to traditional lumbar spine fusion in select patients. Larger clinical series are necessary to validate that clinical improvements are sustained and that arthrodesis rates are

  10. The impact of sagittal balance on clinical results after posterior interbody fusion for patients with degenerative spondylolisthesis: A Pilot study

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    Chung Sung-Soo

    2011-04-01

    Full Text Available Abstract Background Comparatively little is known about the relation between the sagittal vertical axis and clinical outcome in cases of degenerative lumbar spondylolisthesis. The objective of this study was to determine whether lumbar sagittal balance affects clinical outcomes after posterior interbody fusion. This series suggests that consideration of sagittal balance during posterior interbody fusion for degenerative spondylolisthesis can yield high levels of patient satisfaction and restore spinal balance Methods A retrospective study of clinical outcomes and a radiological review was performed on 18 patients with one or two level degenerative spondylolisthesis. Patients were divided into two groups: the patients without improvement in pelvic tilt, postoperatively (Group A; n = 10 and the patients with improvement in pelvic tilt postoperatively (Group B; n = 8. Pre- and postoperative clinical outcome surveys were administered to determine Visual Analogue Pain Scores (VAS and Oswestry disability index (ODI. In addition, we evaluated full spine radiographic films for pelvic tilt (PT, sacral slope (SS, pelvic incidence (PI, thoracic kyphosis (TK, lumbar lordosis (LL, sacrofemoral distance (SFD, and sacro C7 plumb line distance (SC7D Results All 18 patients underwent surgery principally for the relief of radicular leg pain and back pain. In groups A and B, mean preoperative VAS were 6.85 and 6.81, respectively, and these improved to 3.20 and 1.63 at last follow-up. Mean preoperative ODI were 43.2 and 50.4, respectively, and these improved to 23.6 and 18.9 at last follow-up. In spinopelvic parameters, no significant difference was found between preoperative and follow up variables except PT in Group A. However, significant difference was found between the preoperative and follows up values of PT, SS, TK, LL, and SFD/SC7D in Group B. Between parameters of group A and B, there is borderline significance on preoperative PT, preoperative LL and last

  11. Structural and mechanical evaluations of a topology optimized titanium interbody fusion cage fabricated by selective laser melting process.

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    Lin, Chia-Ying; Wirtz, Tobias; LaMarca, Frank; Hollister, Scott J

    2007-11-01

    A topology optimized lumbar interbody fusion cage was made of Ti-Al6-V4 alloy by the rapid prototyping process of selective laser melting (SLM) to reproduce designed microstructure features. Radiographic characterizations and the mechanical properties were investigated to determine how the structural characteristics of the fabricated cage were reproduced from design characteristics using micro-computed tomography scanning. The mechanical modulus of the designed cage was also measured to compare with tantalum, a widely used porous metal. The designed microstructures can be clearly seen in the micrographs of the micro-CT and scanning electron microscopy examinations, showing the SLM process can reproduce intricate microscopic features from the original designs. No imaging artifacts from micro-CT were found. The average compressive modulus of the tested caged was 2.97+/-0.90 GPa, which is comparable with the reported porous tantalum modulus of 3 GPa and falls between that of cortical bone (15 GPa) and trabecular bone (0.1-0.5 GPa). The new porous Ti-6Al-4V optimal-structure cage fabricated by SLM process gave consistent mechanical properties without artifactual distortion in the imaging modalities and thus it can be a promising alternative as a porous implant for spine fusion.

  12. TranS1 VEO system: a novel psoas-sparing device for transpsoas lumbar interbody fusion

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    Hardenbrook MA

    2013-06-01

    Full Text Available Mitchell A Hardenbrook,1,2 Larry E Miller,3,4 Jon E Block4 1Advanced Spine Institute of Greater Boston, North Billerica, MA, 2Department of Orthopedic Surgery, Tufts University School of Medicine, Boston, MA, 3Miller Scientific Consulting Inc, Arden, NC, 4The Jon Block Group, San Francisco, CA, USA Abstract: Minimally invasive approaches for lumbar interbody fusion have been popularized in recent years. The retroperitoneal transpsoas approach to the lumbar spine is a technique that allows direct lateral access to the intervertebral disc space while mitigating the complications associated with traditional anterior or posterior approaches. However, a common complication of this procedure is iatrogenic injury to the psoas muscle and surrounding nerves, resulting in postsurgical motor and sensory deficits. The TranS1 VEO system (TranS1 Inc, Raleigh, NC, USA utilizes a novel, minimally invasive transpsoas approach to the lumbar spine that allows direct visualization of the psoas and proximal nerves, potentially minimizing iatrogenic injury risk and resulting clinical morbidity. This paper describes the clinical uses, procedural details, and indications for use of the TranS1 VEO system. Keywords: fusion, lateral, lumbar, minimally invasive, transpsoas, VEO

  13. Structural and mechanical evaluations of a topology optimized titanium interbody fusion cage fabricated by selective laser melting process.

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    Lin, Chia-Ying; Wirtz, Tobias; LaMarca, Frank; Hollister, Scott J

    2007-11-01

    A topology optimized lumbar interbody fusion cage was made of Ti-Al6-V4 alloy by the rapid prototyping process of selective laser melting (SLM) to reproduce designed microstructure features. Radiographic characterizations and the mechanical properties were investigated to determine how the structural characteristics of the fabricated cage were reproduced from design characteristics using micro-computed tomography scanning. The mechanical modulus of the designed cage was also measured to compare with tantalum, a widely used porous metal. The designed microstructures can be clearly seen in the micrographs of the micro-CT and scanning electron microscopy examinations, showing the SLM process can reproduce intricate microscopic features from the original designs. No imaging artifacts from micro-CT were found. The average compressive modulus of the tested caged was 2.97+/-0.90 GPa, which is comparable with the reported porous tantalum modulus of 3 GPa and falls between that of cortical bone (15 GPa) and trabecular bone (0.1-0.5 GPa). The new porous Ti-6Al-4V optimal-structure cage fabricated by SLM process gave consistent mechanical properties without artifactual distortion in the imaging modalities and thus it can be a promising alternative as a porous implant for spine fusion. PMID:17415762

  14. 颈椎椎体间融合器的临床应用(附135例报告)%Anterior Decompression and Fusion with Cages in the Cervical Spine

    Institute of Scientific and Technical Information of China (English)

    陈德玉; 赵定麟; 贾连顺; 倪斌; 肖建如; 沈强; 叶晓健; 朱海波

    2001-01-01

    To observe and compare the stability and fusion rate of three kinds of the interbody fusion cages after anterior decompression in the cervical spine.Methods:135 patients with cervical spondylosis and disc herniation were stabilized by using interbody fusion cages after anterior decompression,among them,65 cases with BAK,42 cases with CHTF and 28 cases with InterFix technique.X-ray films and CT were taken after operation to observe the stability and fusion of the segments.Results:The patients were followed up from 8 months to 31 months.The operated segments were stable.There was no difference in the fusion rate among three interbody fusion techniques.Conclusion:The immediate stability of the operated segments can be obtained by using interbody fusion cages.These techniques eliminate the complications of autograft and may be an alternative for replacing the traditional cervical interbody fusion with bone graft.%目的:观察比较3种颈椎椎体间融合器前路减压后椎体间融合的固定及融合效果。方法:采用BAK、CHTF和InterFix?3种颈椎椎体间融合器行颈椎病及颈椎间盘突出症前路减压后椎体间融合135例,其中BAK 65例,CHTF 42例,InterFix 技术28例。术后颈椎X线片及CT检查,观察手术椎节的稳定性和融合情况。结果:随访8~31月,施术节段稳定,3种颈椎椎体间融合器固定融合率无显著差异。结论:颈椎椎体间固定融合技术使施术椎节立即稳定,避免了自体植骨引起的并发症,可作为替代传统颈前路椎体间植骨融合术的方法之一。

  15. A comparison of unilateral and bilateral pedicle screw fixation combined with transforaminal lumbar interbody fusion for lumbar degenerative diseases

    Institute of Scientific and Technical Information of China (English)

    Yang Xiaoming; Wang Hong; Zhao Quanlai; Xu Hongguang; Liu Ping; Jin Yuelong

    2014-01-01

    Background Bilateral transpedicular screw fixation in conjunction with interbody fusion is widely used to treat lumbar degenerative diseases; however,there are some disadvantages of using this fixation system.This study comparatively analyzes the results of unilateral and bilateral pedicle screw fixation combined with transforaminal lumbar interbody fusion (TLIF) for one-level lumbar degenerative diseases.Methods Sixty-six cases with one-level lumbar degenerative diseases were studied.The patients were divided according to surgical approach into a unilateral group (Group A) and a bilateral group (Group B).The patients were evaluated for pain by visual analog scale (VAS) and Oswestry Disability Index (ODI).Operating time,blood loss,duration of hospitalization,and complication rate were also evaluated.Patients were examined at 1,3,6,and 12 months postoperatively and every year thereafter.Results Group A patients' average preoperative VAS and ODI scores were 7.03 ± 0.98 and (64.22±6.38)%,respectively,significantly decreased to 2.91 ± 0.88 and (14.42±2.08)%,respectively,at the last follow-up (P =0.000).In Group B,the average preoperative VAS and ODI scores were 6.79±0.86 and (63.22±4.70)%,respectively,significantly decreased to 3.12±0.96 and (14.62±2.08)%,respectively,at the last follow-up (P=0.000).No significant difference in the duration of hospitalization was found between groups.Operating time and blood loss of (125.9±13.0) minutes and (211.4±28.3) ml,respectively,in Group A were significantly less than (165.2±15.3) minutes and (258.6±18.3) ml,respectively,in Group B (P=-0.000).All patients achieved good bone union and had no pseudarthrosis at the last follow-up.Conclusions There are no clinical differences between unilateral and bilateral pedicle screw fixation combined with TLIF for one-level lumbar degenerative diseases.Unilateral fixation reduces operating time,bleeding,and cost of hospitalization.

  16. Retrospective cost analysis of cervical laminectomy and fusion versus cervical laminoplasty in the treatment of cervical spondylotic myelopathy

    OpenAIRE

    Warren, Daniel T.; Ricart-Hoffiz, Pedro A.; Andres, Tate M.; Hoelscher, Christian M.; Protopsaltis, Themistocles S.; Goldstein, Jeffrey A; Bendo, John A.

    2013-01-01

    Background Cervical laminoplasty (CLP) and posterior cervical laminectomy and fusion (CLF) are well-established surgical procedures used in the treatment of cervical spondylotic myelopathy (CSM). In situations of clinical equipoise, an influential factor in procedural decision making could be the economic effect of the chosen procedure. The object of this study is to compare and analyze the total hospital costs and charges pertaining to patients undergoing CLP or CLF for the treatment of CSM....

  17. Anterior cervical discectomy and fusion with titanium cages for simple or multilevel herniated discs and spur of the cervical spine: Report of 2 cases and experience in Bali

    Science.gov (United States)

    Mahadewa Tjokorda, G. B.; Nyoman, Golden; Sri, Maliawan; Junichi, Mizuno

    2016-01-01

    This report presents two cases of cervicobrachialgia and radiculopathy due to multiple cervical herniated discs and spur formation that dealt with anterior cervical discectomy and fusion (ACDF) using different titanium interbody cages. The description of the clinical presentation, magnetic resonance imaging (MRI) appearances and management strategy are discussed. Both cases showed chronic neck pain and radiating pain from the shoulder to the arm. They had a history of blurry vision, cluster head ache, weakness, and numbness on the shoulder for 2 years. MRI revealed multiple herniated discs between C4-7 and accompanied by the spur formation leading to the narrowness of the spinal canal and its foramina bilaterally. ACDF were performed and complete decompression of the spinal canal and its foramina were carried out. Twin M-cages (Ammtec Inc.-Japan) were placed in the first case at C5-7 levels and single cage of Smith Robinson (SR) was placed in the second case at C5-6 levels. There were no more blurry vision, cluster headache, weakness, and numbness, immediately after surgery. To our knowledge, this is the first reported cases of ACDF, using twin M-cages and single SR cage in Indonesia, with improvement immediately after surgery. Cervical spondylosis can present with cervicobrachialgia and radiculopathy and surgical treatment produces good functional outcome. PMID:27695567

  18. Distracted cervical spinal fusion for management of caudal cervical spondylomyelopathy in large-breed dogs

    International Nuclear Information System (INIS)

    Using an autogenous bone graft (obtained from the iliac crest), 4-mm cancellous bone screws, and polymethylmethacrylate, a distracted cervical spinal fusion technique was performed on 10 dogs with myelographic evidence of caudal cervical spondylomyelopathy. All dogs had evidence of dynamic soft tissue spinal cord compression, as indicated by flexion, extension, and traction myelographic views. Of the 10 dogs, 4 previously had undergone surgery by use of ventral slot or cervical disk fenestration techniques, and their neurologic status had deteriorated after the original surgery. Preoperative neurologic status of the 10 dogs included nonambulatory tetraparesis (n = 5), severe ataxia with conscious proprioceptive deficits (n = 2), and mild ambulatory ataxia with conscious proprioceptive deficits (n = 3). Five dogs had signs of various degrees of cervical pain. Clinical improvement was observed in 8 of 10 dogs--either improved neurologic status or elimination of cervical pain. Implant loosening developed in 3 dogs; 2 of them were euthanatized because of lack of neurologic improvement. Radiographic evidence of bony cervical fusion was observed during a 9- to 24-week period in 6 of the 8 surviving dogs. The distracted cervical fusion technique appears to be a valid surgical procedure to manage cervical spondylomyelopathy in those dogs in which the lesions are limited to one cervical intervertebral disk space

  19. Evaluation of an injectable silk fibroin enhanced calcium phosphate cement loaded with human recombinant bone morphogenetic protein-2 in ovine lumbar interbody fusion.

    Science.gov (United States)

    Gu, Yong; Chen, Liang; Yang, Hui-Lin; Luo, Zong-Ping; Tang, Tian-Si

    2011-05-01

    The objective of this study was to investigate the efficacy of an injectable calcium phosphate cement/silk fibroin/human recombinant bone morphogenetic protein-2 composite (CPC/SF/rhBMP-2) in an ovine interbody fusion model. Twenty-four mature sheep underwent anterior lumbar interbody fusion at the levels of L1/2, L3/4, and L5/6 with random implantation of CPC/SF, CPC/rhBMP-2, CPC/SF/rhBMP-2, or autogenous iliac bone. After the sheep were sacrificed, the fusion segments were evaluated by manual palpation, CT scan, undestructive biomechanical testing, undecalcified histology, and histomorphology. The fusion rates of CPC/SF/rhBMP-2 were 55.56% and 77.78% at 6 and 12 months, respectively. The fusion was superior to all the biomaterial grafts in stiffness, and reached the same stiffness as the autograft at 12 months. The new bone formation was less than autograft at 6 months, but similar with that at 12 months. However, the ceramic residue volume of CPC/SF/rhBMP-2 was significantly decreased compared with CPC/SF and CPC/rhBMP-2 at both times. The results indicated that CPC/SF/rhBMP-2 composite had excellent osteoconduction and osteoinduction, and balanced degradation and osteogenesis.

  20. Clinical study on minimally invasive transforaminal lumbar interbody fusion combined with percutaneous pedicle screw fixation for degenerative lumbar scoliosis

    Directory of Open Access Journals (Sweden)

    Hao WU

    2016-04-01

    Full Text Available Objective To discuss the operative essentials and therapeutic effects of minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF combined with percutaneous pedicle screw fixation for degenerative lumbar scoliosis (DLS.  Methods A total of 17 DLS patients without prior spinal diseases were treated by MIS-TLIF and percutaneous pedicle screw fixation from January 2013 to September 2015 in Xuanwu Hospital, Capital Medical University. The operation time, intraoperative blood loss, hospital stay, and postoperative complication were recorded in each patient. Visual Analogue Scale (VAS and Oswestry Disability Index (ODI were used to evaluate postoperative improvement of low back and leg pain, and clinical effects were assessed according to Medical Outcome Study 36-Item Short-Form Health Survey (SF-36. Coronal Cobb angle, sagittal lordosis angle and spinal deviation distances on coronal and sagittal plane were measured before operation, one week, 3 months after operation and in the last follow-up in spinal full-length X-ray examination. Fusion rate was calculated according to X-ray or CT scan, and the degree of decompression was evaluated by MRI.  Results Decompression and fusion levels ranged from T12-S1 vertebrae, and interbody fusion was performed in 17 patients and 56 levels were fused. Average operation time was 200 min (180-300 min, intraoperative blood loss was 320 ml (200-1000 ml and hospital stay was 8.21 d (5-12 d. All patients were followed-up for 12.13 months (5-24 months. Compared with preoperation, VAS (P = 0.000, for all and ODI scores (P = 0.000, for all decreased significantly, SF-36 score increased (P = 0.000, for all, coronal Cobb angle (P = 0.000, for all, sagittal lordosis angle (P = 0.000, for all, coronal and sagittal deviation (P = 0.000, for all decreased significantly one week and 3 months after operation and in the last follow-up. The improvement rate of ODI was (86.51 ± 6.02%, fusion rate of vertebral bodies

  1. 颈椎桥形连接融合器进行双节段以上椎间融合的效果评价%Above two-level segment interbody fusion with double-way connection intervertebral fusion device

    Institute of Scientific and Technical Information of China (English)

    傅宇; 傅云根; 罗嘉全; 曹盛生; 李俊宁; 徐文华

    2013-01-01

    -level cervical interbody fusion. METHODS: Fifty-four patients with above two-level cervical intervertebral disc herination were treated with anterior cervical decompression and fusion. These patients were treated with anterior cervical interbody fusion using double-way connection intervertebral fusion device (n=30) and Cage intervertebral fusion device and anterior plate fixation system (n=24). The clinical results were evaluated with Japanese Orthopedic Association scale scores, and the cervical curvature, intervertebral height and cervical fusion state were tested with X-ray film at 3 and 6 months after interbody fusion. RESULTS AND CONCLUSION: Al patients were fol owed-up for 6 months. The patients in two groups got osseous fusion, and the average fusion time was 5.5 months. Average Japanese Orthopedic Association scale score of double-way connection intervertebral fusion device group was increased from (7.4±0.4) preoperatively to (14.3±0.5) at 3 months and (14.5±0.8) at 6 months postoperatively; and the average Japanese Orthopedic Association scale score of Cage intervertebral fusion device group was increased from (7.6±0.7) preoperatively to (13.9±0.4) at 3 months and (14.0±0.6) at 6 months postoperatively, and the differences were significant. The spinal curvature and intervertebral height were significantly improved after treatment. This procedure can effectively restore cervical lordosis, obviate the complications related to graft harvest and screw-plate fixation, and lead to satisfactory outcomes.

  2. The Effect of the Retroperitoneal Transpsoas Minimally Invasive Lateral Interbody Fusion on Segmental and Regional Lumbar Lordosis

    Directory of Open Access Journals (Sweden)

    Tien V. Le

    2012-01-01

    Full Text Available Background. The minimally invasive lateral interbody fusion (MIS LIF in the lumbar spine can correct coronal Cobb angles, but the effect on sagittal plane correction is unclear. Methods. A retrospective review of thirty-five patients with lumbar degenerative disease who underwent MIS LIF without supplemental posterior instrumentation was undertaken to study the radiographic effect on the restoration of segmental and regional lumbar lordosis using the Cobb angles on pre- and postoperative radiographs. Mean disc height changes were also measured. Results. The mean follow-up period was 13.3 months. Fifty total levels were fused with a mean of 1.42 levels fused per patient. Mean segmental Cobb angle increased from 11.10° to 13.61° (<0.001 or 22.6%. L2-3 had the greatest proportional increase in segmental lordosis. Mean regional Cobb angle increased from 52.47° to 53.45° (=0.392. Mean disc height increased from 6.50 mm to 10.04 mm (<0.001 or 54.5%. Conclusions. The MIS LIF improves segmental lordosis and disc height in the lumbar spine but not regional lumbar lordosis. Anterior longitudinal ligament sectioning and/or the addition of a more lordotic implant may be necessary in cases where significant increases in regional lumbar lordosis are desired.

  3. Remodeling of heat-treated cortical bone allografts for posterior lumbar interbody fusion: serial 10-year follow-up.

    Science.gov (United States)

    Muramatsu, Koichi; Hachiya, Yudo; Izawa, Hiroyuki; Yamada, Harumoto

    2012-12-01

    We have selected heat-treated bone allografts as the graft material since the Tokai Bone Bank, the first regional bone bank in Japan, was established in 1992. In this study, we examined changes in bone mineral density (BMD), and morphology observed by magnetic resonance imaging (MRI), and histological findings of bone grafts in cases followed up for 7-10 years after bone grafting to grasp the remodeling of heat-treated cortical bone allografts for posterior lumber interbody fusion (PLIF). BMD of bone grafts was reduced by half at 10 years after grafting. MRI revealed that bone grafts were indistinguishable initially in only 22.2% of cases, whereas after a lengthy period of 10 years distinguishable in many cases. Histologically, new bone formation at the graft-host interface was observed earlier, at 1 year after grafting, than that at the periphery of canals in the specimens. The laminated structure of the cortical bone eroded over time, and fragmented bone trabeculae were observed in the specimens at 8 years or longer after grafting, though necrotic bone still remained in some sites.

  4. Neurological Complications after Lateral Transpsoas Approach to Anterior Interbody Fusion with a Novel Flat-Blade Spine-Fixed Retractor

    Directory of Open Access Journals (Sweden)

    Pierce Nunley

    2016-01-01

    Full Text Available Introduction. The lateral lumbar interbody fusion (LLIF surgical approach has potential advantages over other approaches but is associated with some unique neurologic risks due to the proximity of the lumbosacral plexus. The present study analyzed complications following LLIF surgical approach using a novel single flat-blade retractor system. Methods. A retrospective data collection of patients receiving LLIF using a novel single flat-blade retractor system at two institutions in the US. Inclusion criteria were all patients receiving an LLIF procedure with the RAVINE® Lateral Access System (K2M, Inc., Leesburg, VA, USA. There was no restriction on preoperative diagnosis or number of levels treated. Approach-related neurologic complications were collected and analyzed postoperatively through a minimum of one year. Results. Analysis included 253 patients with one to four treated lateral levels. Immediate postoperative neurologic complications were present in 11.1% (28/253 of patients. At one-year follow-up the approach-related neurologic complications resolved in all except 5 patients (2.0%. Conclusion. We observed an 11.1% neurologic complication rate in LLIF procedures. There was resolution of symptoms for most patients by 12-month follow-up, with only 2% of patients with residual symptoms. This supports the hypothesis that the vast majority of approach-related neurologic symptoms are transient.

  5. Clinical and radiographic outcomes with L4–S1 axial lumbar interbody fusion (AxiaLIF and posterior instrumentation: a multicenter study

    Directory of Open Access Journals (Sweden)

    Tobler WD

    2013-09-01

    Full Text Available William D Tobler,1 Miguel A Melgar,2 Thomas J Raley,3 Neel Anand,4 Larry E Miller,5 Richard J Nasca6 1Department of Neurosurgery, University of Cincinnati College of Medicine, Mayfield Clinic, and The Christ Hospital, Cincinnati, OH, USA; 2Department of Neurosurgery, Tulane University, New Orleans, LA, USA; 3Advanced Spine and Pain, Arlington, VA, USA; 4Spine Trauma, Minimally Invasive Spine Surgery Spine Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA; 5Miller Scientific Consulting, Inc, Arden, NC, USA; 6Orthopaedic and Spine Surgery, Wilmington, NC, USA Introduction: Previous studies have confirmed the benefits and limitations of the presacral retroperitoneal approach for L5–S1 interbody fusion. The purpose of this study was to determine the safety and effectiveness of the minimally invasive axial lumbar interbody approach (AxiaLIF for L4–S1 fusion. Methods: In this retrospective series, 52 patients from four clinical sites underwent L4–S1 interbody fusion with the AxiaLIF two-level system with minimum 2-year clinical and radiographic follow-up (range: 24–51 months. Outcomes included back pain severity (on a 10-point scale, the Oswestry Disability Index (ODI, and Odom's criteria. Flexion and extension radiographs, as well as computed tomography scans, were evaluated to determine fusion status. Longitudinal outcomes were assessed with repeated measures analysis of variance. Results: Mean subject age was 52 ± 11 years and the male:female ratio was 1:1. Patients sustained no intraoperative bowel or vascular injury, deep infection, or neurologic complication. Median procedural blood loss was 220 cc and median length of hospital stay was 3 days. At 2-year follow-up, mean back pain had improved 56%, from 7.7 ± 1.6 at baseline to 3.4 ± 2.7 (P < 0.001. Back pain clinical success (ie, ≥30% improvement from baseline was achieved in 39 (75% patients at 2 years. Mean ODI scores improved 42%, from 60% ± 16% at baseline to 35% ± 27

  6. Clinical and Radiological Comparison of Femur and Fibular Allografts for the Treatment of Cervical Degenerative Disc Diseases

    OpenAIRE

    Oh, Hyeong-Seok; Shim, Chan Shik; Kim, Jin-Sung; Lee, Sang-Ho

    2013-01-01

    Objective This consecutive retrospective study was designed to analyze and to compare the efficacy and outcomes of anterior cervical discectomy and fusion (ACDF) using a fibular and femur allograft with anterior cervical plating. Methods A total of 88 consecutive patients suffering from cervical degenerative disc disease (DDD) who were treated with ACDF from September 2007 to August 2010 were enrolled in this study. Thirty-seven patients (58 segments) underwent anterior interbody fusion with ...

  7. Biomechanical analysis of a newly developed shape memory alloy hook in a transforaminal lumbar interbody fusion (TLIF in vitro model.

    Directory of Open Access Journals (Sweden)

    Xi Wang

    Full Text Available The objective of this biomechanical study was to evaluate the stability provided by a newly developed shape memory alloy hook (SMAH in a cadaveric transforaminal lumbar interbody fusion (TLIF model.Six human cadaveric spines (L1-S2 were tested in an in vitro flexibility experiment by applying pure moments of ±8 Nm in flexion/extension, left/right lateral bending, and left/right axial rotation. After intact testing, a TLIF was performed at L4-5. Each specimen was tested for the following constructs: unilateral SMAH (USMAH; bilateral SMAH (BSMAH; unilateral pedicle screws and rods (UPS; and bilateral pedicle screws and rods (BPS. The L3-L4, L4-L5, and L5-S1 range of motion (ROM were recorded by a Motion Analysis System.Compared to the other constructs, the BPS provided the most stability. The UPS significantly reduced the ROM in extension/flexion and lateral bending; the BSMAH significantly reduced the ROM in extension/flexion, lateral bending, and axial rotation; and the USMAH significantly reduced the ROM in flexion and left lateral bending compared with the intact spine (p0.05. Stability provided by the USMAH compared with the UPS was not significantly different. ROMs of adjacent segments increased in all fixed constructs (p>0.05.Bilateral SMAH fixation can achieve immediate stability after L4-5 TLIF in vitro. Further studies are required to determine whether the SMAH can achieve fusion in vivo and alleviate adjacent segment degeneration.

  8. Bone graft substitutes in anterior cervical discectomy and fusion

    OpenAIRE

    Chau, Anthony M.T.; Mobbs, Ralph J.

    2009-01-01

    Anterior cervical discectomy with fusion is a common surgical procedure for patients suffering pain and/or neurological deficits and unresponsive to conservative management. For decades, autologous bone grafted from the iliac crest has been used as a substrate for cervical arthrodesis. However patient dissatisfaction with donor site morbidity has led to the search for alternative techniques. We present a literature review examining the progress of available grafting options as assessed in hum...

  9. Fusion of Adjacent Segment Degeneration after Anterior Portion Cervical Decompression%颈前路融合术后相邻节段退变120例

    Institute of Scientific and Technical Information of China (English)

    占蓓蕾; 叶舟

    2014-01-01

    目的:探讨颈椎前路减压融合术后相邻节段退变的因果关系。方法:对237例患者行前路椎间节段减压植骨融合术(87例),椎体次全切除减压植骨融合术(109例),椎间节段减压、椎体次全切除减压植骨融合术(41例)。通过影像学检查,观察不同手术方法术后相邻节段退变发生情况。结果:术后随访时间2.6~13年,平均6.8年;发生相邻节段明显退变的120例(50.6%),头侧相邻节段退变发生率明显高于尾侧邻近节段(P<0.05),其中27例(22.2%)需2次翻修手术。结论:颈椎前路融合术后可导致颈椎相邻节段的退变。%Objective To investigate the result of anterior cervical decompression and fusion of adjacent segment degeneration after causality. Methods among 237 patients(87 cases) weretreated with anterior decom-pression and interbody fusion intervertebral segments, 109cases with subtotal excision of the vertebral body with decompression and interbody fusion,and 41 cases with intervertebral segmental decompression, vertebral body subtotal resection decompression and interbody fusion.By imaging examination, different surgical methods and postoperative adjacent segment degeneration were observed. Results Postoperative follow-up at time of 2.6~13 years, averaging 6.8 years; showed significantly degeneration of adjacent segments in 120 cases (50.6%), the cranial adjacent segment degeneration rate significantly higher than that of the caudal adjacent segment (P<0.05), among them,27 cases (22.2%)needed 2 times of revision surgery. Conclusion The anterior cervical fu-sion surgery can lead to cervical vertebral adjacent segment degeneration.

  10. Surgeons' exposure to radiation in single- and multi-level minimally invasive transforaminal lumbar interbody fusion; a prospective study.

    Directory of Open Access Journals (Sweden)

    Haruki Funao

    Full Text Available Although minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF has widely been developed in patients with lumbar diseases, surgeons risk exposure to fluoroscopic radiation. However, to date, there is no studies quantifying the effective dose during MIS-TLIF procedure, and the radiation dose distribution is still unclear. In this study, the surgeons' radiation doses at 5 places on the bodies were measured and the effective doses were assessed during 31 consecutive 1- to 3-level MIS-TLIF surgeries. The operating surgeon, assisting surgeon, and radiological technologist wore thermoluminescent dosimeter on the unshielded thyroid, chest, genitals, right middle finger, and on the chest beneath a lead apron. The doses at the lens and the effective doses were also calculated. Mean fluoroscopy times were 38.7, 53.1, and 58.5 seconds for 1, 2, or 3 fusion levels, respectively. The operating surgeon's mean exposures at the lens, thyroid, chest, genitals, finger, and the chest beneath the shield, respectively, were 0.07, 0.07, 0.09, 0.14, 0.32, and 0.05 mSv in 1-level MIS-TLIF; 0.07, 0.08, 0.09, 0.18, 0.34, and 0.05 mSv in 2-level; 0.08, 0.09, 0.14, 0.15, 0.36, and 0.06 mSv in 3-level; and 0.07, 0.08, 0.10, 0.15, 0.33, and 0.05 mSv in all cases. Mean dose at the operating surgeon's right finger was significantly higher than other measurements parts (P<0.001. The operating surgeon's effective doses (0.06, 0.06, and 0.07 mSv for 1, 2, and 3 fusion levels were low, and didn't differ significantly from those of the assisting surgeon or radiological technologist. Revision MIS-TLIF was not associated with higher surgeons' radiation doses compared to primary MIS-TLIF. There were significantly higher surgeons' radiation doses in over-weight than in normal-weight patients. The surgeons' radiation exposure during MIS-TLIF was within the safe level by the International Commission on Radiological Protection's guidelines. The accumulated radiation exposure

  11. Cervical vertebral body fusions in patients with skeletal deep bite.

    Science.gov (United States)

    Sonnesen, Liselotte; Kjaer, Inger

    2007-10-01

    Cervical column morphology was examined in 41 adult patients with a skeletal deep bite, 23 females aged 22-42 years (mean 27.9) and 18 males aged 21-44 years (mean 30.8) and compared with the cervical column morphology in an adult control group consisting of 21 subjects, 15 females, aged 23-40 years (mean 29.2 years) and six males aged 25-44 years (mean 32.8 years) with neutral occlusion and normal craniofacial morphology. None of the patients or control subjects had received orthodontic treatment. For each individual, a visual assessment of the cervical column and measurements of the cranial base angle, vertical craniofacial dimensions, and morphology of the mandible were performed on a profile radiograph. In the deep bite group, 41.5 per cent had fusion of the cervical vertebrae and 9.8 per cent posterior arch deficiency. The fusion always occurred between C2 and C3. No statistically significant gender differences were found in the occurrence of morphological characteristics of the cervical column (females 43.5 per cent, males 38.9 per cent). Morphological deviations of the cervical column occurred significantly more often in the deep bite group compared with the control group (P analysis showed that the vertical jaw relationship (P vertebrae (R(2) = 0.40).

  12. 生物活性颈椎椎间融合器在颈椎融合术中不同固定方式的生物力学研究%Biomechanical study of bioactive cervical fusion cage with different types of fixation in cervical spinal fusion

    Institute of Scientific and Technical Information of China (English)

    胡孔和; 吴强; 段扬; 包拥政; 靳安民; 赵卫东

    2012-01-01

    目的 探讨由羟基磷灰石和左旋聚乳酸复合研制的新型生物活性颈椎椎间融合器在颈椎融合术中不同固定方式的生物力学特性.方法 制备新鲜人颈椎标本6个(尸体均为合法捐赠,由南方医科大学解剖学教研室提供),模拟临床术式行前路C5~6减压椎间分别植入髂骨、生物活性颈椎椎间融合器和生物活性颈椎椎间融合器加钢板内固定,通过脊柱三维运动实验机测量C5~6节段的运动范围.结果 生物活性颈椎椎间融合器加钢板固定后稳定性增加,在各个状态的运动范围均明显小于其他各组(P <0.005).单纯生物活性颈椎椎间融合器组在后伸状态下运动范围(6.25±0.29)度较正常组(5.76±0.40)度增大,稳定性下降,但差异无统计学意义(P>0.05);在除后伸外的其他各种状态下的运动范围均小于髂骨组,较髂骨组稳定,差异有统计学意义(P<0.005).结论 新型生物活性颈椎椎间融合器具有良好的生物力学性能,加钢板内固定后各个方向稳定性好,能重建颈椎稳定性.%Objective To investigate the biomechanical characteristics of different types of fixation with bioactive cervical fusion cage made of hydroxyapatite and poly L-lactic acid in cervical spinal fusion.Methods Iliac crest bone,bioactive cervical fusion cage and bioactive cervical fusion cage with plate fixation were used for anterior interbody implants after anterior discectomy across C5-6 in six fresh human cervical spine specimens respectively,and the range of motion of the cervical vertebrae interbody fusion were measured through the motional stability test.Results After discectomy,Bioactive Cervical Fusion Cage with plate fixation exhibited a significant increase in stability and a decrease of range of motion in angular motion than others in all motional directions ( P < 0.005 ). Bioactive cervical fusion cage exhibited a decrease in stability and an increase of range of motion (6.25

  13. Comparison of Topping-off and posterior lumbar interbody fusion surgery in lumbar degenerative disease:a retrospective study

    Institute of Scientific and Technical Information of China (English)

    LIU Hai-ying; ZHOU Jian; WANG Bo; WANG Hui-min; JIN Zhao-hui; ZHU Zhen-qi; MIAO Ke-nan

    2012-01-01

    Background Topping-off surgery is a newly-developed surgical technique which combines rigid fusion with an interspinous process device in the adjacent segment to prevent adjacent segment degeneration.There are few reports on Topping-off surgery and its rationality and indications remains highly controversial.Our study aims to investigate the short-term and mid-term clinical results of Topping-off surgery in preventing adjacent segment degeneration when mild or moderate adjacent segment degeneration existed before surgery.Methods The 25 cases that underwent L5-S1 posterior lumbar interbody fusion(PLIF)+L4-L5 interspinous process surgeries between April 2008 and March 2010 formed Topping-off group.The 42 cases undergoing L5-S1 PLIF surgery formed PLIF group.Both groups matched in gender,age,body mass index and Pfirrmann grading(4 to 6).The patients were evaluated with visual analogue scale(VAS)and Japanese orthopaedic association(JOA)scores before surgery and in the last follow-up.Modic changes of endplates were recorded.Results The follow-up averaged 24.8 and 23.7 months.No symptomatic or radiological adjacent segment degeneration was observed.There was no significant difference in intraoperative blood loss or postoperative drainage.VAS and lumbar JOA scores improved significantly in both groups(t=12.1 and 13.5,P<0.05).Neither anterior nor posterior disc height was significantly changed.Segmental lordosis of L4-L5 and total lordosis were all increased significantly(Topping-off group:t=-2.30 and-2.24,P<0.05;PLIF group:t=-2.76 and-1.83,P<0.01).In the hyperextension and hyperflexion view,Topping-off group's range of motion(ROM)and olisthesis in the L4-L5 segment did not significantly change in flexion,but decreased in extension.In PLIF group,ROM(t=-7.82 and-4.90,P<0.01)and olisthesis(t=-15.67and-18.58,P<0.01)both significantly increased in extension and flexion.Conclusions Compared with single segment PLIF surgery,Topping-off surgery can achieve similar

  14. Effect of Anterior Cervical Discectomy and Fusion on Patients with Atypical Symptoms Related to Cervical Spondylosis.

    Science.gov (United States)

    Muheremu, Aikeremujiang; Sun, Yuqing; Yan, Kai; Yu, Jie; Zheng, Shan; Tian, Wei

    2016-09-01

    Background A considerable number of patients with cervical spondylosis complain about one or multiple atypical symptoms such as vertigo, palpitations, headache, blurred vision, hypomnesia, and/or nausea. It remains unclear whether surgical intervention for cervical spondylosis can also effectively alleviate those symptoms. The current study was performed to see if anterior cervical diskectomy and fusion (ACDF) offers such an extra benefit for patients with cervical spondylosis. Objective To investigate if patients who received ACDF for the treatment of cervical spondylotic myelopathy and/or radiculopathy can also achieve alleviation of certain atypical symptoms associated with cervical spondylosis after the surgery in the long run. Methods Sixty-seven patients who underwent ACDF for the treatment of cervical spondylotic myelopathy and/or radiculopathy were involved in this study. All these patients also complained about various associated atypical symptoms. They were followed up for 26 to 145 months after the surgery. Severity and frequency scores of the atypical symptoms before the surgery and at last follow-up were compared by paired t tests. Results Most patients reported significantly alleviated symptoms at the last follow-up compared with before the surgery. The severity of vertigo, headache, nausea, and palpitations were significantly alleviated at the last follow-up (with p values of p cervical spondylotic myelopathy and/or radiculopathy, but it is not effective in alleviating symptoms such as tinnitus, blurred vision, and hypomnesia. It can be considered for alleviating atypical symptoms when other treatment options prove ineffective. PMID:27168319

  15. Is the transsacral axial interbody fusion a candidate surgical approach for fusing both L5/S1 and L4/5?

    Institute of Scientific and Technical Information of China (English)

    LIU Bi-feng; ZHANG Li-guo; LIU Yan-bin; YAN Ning; ZHANG Hai-long; GU Xin; DING Yue; GUO Cheng-bin; HE Shi-sheng

    2011-01-01

    Background Previous clinical and basic research of axial lumbar interbody fusion (AxiaLIF) all focused on the L5/S1.However,there is no data on the feasibility of this approach for the fusion of both L4/5 and L5/S1.This study aimed to explore whether transsacral axial interbody fusion is a candidate for the fusion of both L4/5 and L5/S1.Methods The subjects (n=40) underwent lumbosacral magnetic resonance imaging (MRI).The median sagittal MRI images were analyzed and five measurement markers were defined as follows:the center of the L4/5 disc (A),the center of the L5/S1 disc (B),the anterior margin of the S1/2 space (C),the sacrococcygeal junction (D),and the coccygeal tip (E).The measurement markers were connected each other to produce nine lines (AB,AC,AD,AE,BC,BD,BE,CD and CE) as the reference lines for surgical approaches.The distance between each reference line and the anterior and posterior margins of the L4,L5 and S1 vertebral bodies were measured to determine the safety of the respective approaches.Results Twenty subjects were capable of finding one reference line to fuse both L4/5 and L5/S1 via transsacral axial interbody fusion approach.The surgical approach reference line was AE or CE line.In the other 20 subjects,it was failed to find a reference line which met the safety criteria for fusing both L4/5 and L5/S1.Conclusions About half of subjects were capable of finding a suitable AxiaLIF reference line to fuse both L4/5 and L5/S1.In some subjects,it was difficult to find a suitable AxiaLIF reference line to fuse both L4/5 and L5/S1.

  16. Anterior cervical decompression and fusion with caspar plate fixation

    International Nuclear Information System (INIS)

    Objective: To evaluate the role of anterior cervical decompression and fixation with Caspar plating in cervical spine injury on neurological outcome. Study Design: A case series. Place and Duration of Study: Department of Neurosurgery, Jinnah Postgraduate Medical Centre, Karachi, from July 2008 to March 2011. Methodology: Thirty patients admitted with cervical spine injuries were inducted in the study. All cases were evaluated for their clinical features, level of injury and degree of neurological injury was assessed using Frankel grading. Pre and postoperative record with X-rays and MRI were maintained. Cervical traction was applied to patients with sub-luxation. All patients underwent anterior cervical decompression, fusion and Caspar plate fixation. The follow-up period was 6 months with clinical and radiological assessment. Results: Among 30 patients, 24 (80%) were males and 6 (20%) were females. Age ranged from 15 to 55 years. Causes of injury were road traffic accident (n = 20), fall (n = 8) and assault (n = 2). Commonest mode of injury was road traffic accident (66.6%). Postoperative follow-up showed that pain and neurological deficit were improved in 21 patients. There was no improvement in 7 patients, one patient deteriorated and one expired. All patients developed pain at donor site. Conclusion: Anterior decompression, fusion and fixation with Caspar plate is an effective method with good neurological and radiological outcome. However, it is associated with pain at donor site. (author)

  17. Anterior cervical fusion versus minimally invasive posterior keyhole decompression for cervical radiculopathy

    Directory of Open Access Journals (Sweden)

    Richard M. Young

    2015-12-01

    Conclusion: ACDF has been demonstrated to be an effective surgical procedure in treating degenerative spine disease in patients with radiculopathy and/or myelopathy. However, in a population with isolated radiculopathy and radiological imaging confirming an anterolateral disc or osteophyte complex, the MIPKF can provide similar results without the associated risks that accompany an anterior cervical spine fusion.

  18. Comparison of the clinical effect between posterior lumbar interbody fusion and transforaminal lumbar interbody fusion in the treatment of degenerative spondylolithesis and instability%后路腰椎椎体间融合与经椎间孔腰椎椎体间融合治疗退行性腰椎滑脱与不稳疗效比较

    Institute of Scientific and Technical Information of China (English)

    罗远明; 徐跃根; 卢厚微; 杨东方

    2012-01-01

    Objective To compare the therapeutic effect of posterior lumbar interbody fusion ( PLIF ) and transforami-nal lumbar interbody fusion ( TLIF ) with pedicle screw fixation on treatment in lumbar degenerative disease. Methods 86 patients were underwent PLIF( PLIF group ) and 76 cases were underwent TLIF( TLIF group ) with one cage and pedicle fixation in 162 patients with lumbar degenerative disease. Operating time and blood loss were quantified, average slip and reduction rate in spondylolithesis, average intervertebral and foramen height were evaluated in preop-eration and postoperation. Pain recorded according to visual analogue scale( VAS ) , functional disability according to oswestry disablity index ( ODI ), and bone graft fusion rate according to Brantigan and Steffee criteria. Results Compared to PLIF group, it took shorter operating time and less blood loss in TLIF group, there was no statistical significance in spondylolithesis, reduction rate, intervertebral and foramen height, VAS, ODI, bone graft fusion rate between the two groups( P >0. 05 ), but there was fewer complications in TLIF group( P 0.05).结论 PLIF与TLIF均为手术治疗退行性脊柱滑脱与不稳的有效方法,而TLIF手术时间短、失血量少,并发症少.

  19. Posterior lumbar inter-body fusion (PLIF) using autogenous bone and cage with pedicle screw instrumentation versus PLIF using cage with pedicle screw instrumentation in adult spondylolisthesis

    Institute of Scientific and Technical Information of China (English)

    Dou Yusheng; Hao Dingjun; Wen Shiming

    2005-01-01

    Objective: To compare the clinical outcomes of PLIF using autogenous bone and cage with pedicle screw fixation (group 2) and simple cage fusion with pedicle screw fixation (group 1) in adult spondylolisthesis.Methods: 27 patients with minimum follow-up of 24 months, treated by inter-body fusion with pedicle screw fixation were prospectively studied. Disc space height, degree of slippage and fusion rate had been compared before and after operation between the two groups. Results: After minimum 24 month's follow-up, there was no significant difference between the two groups in terms of the amount of blood loss, duration of hospital stay, back pain,radiating pain, fusion rate, or complication (P>0.05). however, there was a significant difference between the two groups in terms of disc space height and percentage of slippage (P<0.05). Conclusion: PLIF using autogenous bone and cage with pedicle screw fixation more beneifical to improve fusion rate and prevent long-term instabilities than simple cage fusion with pedicle screw fixation in adult spondylolisthesis.

  20. Comparing minimally invasive and open transforaminal lumbar interbody fusion for treatment of degenerative lumbar disease: a meta-analysis

    Institute of Scientific and Technical Information of China (English)

    SUN Zhi-jian; LI Wen-jing; ZHAO Yu; QIU Gui-xing

    2013-01-01

    Background Transforaminal lumbar interbody fusion (TLIF) through a minimally invasive approach (mTLIF) was introduced to reduce soft tissue injury and speed recovery.Studies with small numbers of patients have been carried out,comparing mTLIF with traditional open TLIF (oTLIF),but inconsistent outcomes were reported.Methods We conducted a meta-analysis to evaluate the effectiveness of mTLIF and oTLIF in the treatment of degenerative lumbar disease.We searched PubMed,Embase and Cochrane Database of Systematic Reviews in March 2013 for studies directly comparing mTLIF and oTLIF.Patient characteristics,interventions,surgical-related messages,early recovery parameters,long-term clinical outcomes,and complications were extracted and relevant results were pooled.Results Twelve cohort studies with a total of 830 patients were identified.No significant difference regarding average operating time was observed when comparing mTLIF group with oTLIF group (-0.35 minute,95% confidence interval (C/):-20.82 to 20.13 minutes).Intraoperative blood loss (-232.91 ml,95% CI:-322.48 to-143.33 ml) and postoperative drainage (-111.24.ml,95% CI:-177.43 to-45.05 ml) were significantly lower in the mTLIF group.A shorter hospital stay by about two days was observed in patients who underwent mTLIF (-2.11 days,95% CI:-2.76 to-1.45 days).With regard to long-term clinical outcomes,no significant difference in visual analog scale score (-0.25,95% CI:-0.63 to 0.13) was observed; however,there was a slight improvement in Oswestry Disability Index (-1.42,95% CI:-2.79 to-0.04) during a minimum of 1-year follow-up between the two groups.The incidence of complications did not differ significantly between the procedures (RR=1.06,95% CI:0.7 to 1.59).Reoperation was more common in patients in mTLIF group than in oTLIF group (5% vs.2.9%),but this difference was not significant (RR=1.62,95% CI:0.75 to 3.51).Conclusion Current evidence suggests that,compared with traditional open surgery

  1. Multilevel cervical spondylotic myelopathy treated by anterior cervical decompression in subsection and autograft fusion

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Objective:To investigate a novel surgical method for multilevel cervical spondylotic myelopathy (CSM). Methods: Totally 21 patients with multilevel CSM undergoing a novel surgical procedure from April 2001 to January 2004 were analyzed retrospectively. All patients experienced anterior cervical decompression surgery in subsection, autograft fusion and internal fixation. Preoperative, immediate postoperative and follow-up image data, X-rays and semi-quantitative Japanese orthopaedics association (JOA) scores were used to evaluate the restoration of lordosis (Cobb's angle), intervertebral heights, the stability of the cervical spine and the improvement of neurological impairment. Results: Preoperative symptoms were markedly alleviated or disappeared in most of the patients. According to the JOA scores, the ratio of improvement in neurological function was 72.2%, including excellent in 9 cases (42.9%), good in 7 cases (33.3%), fair in 3 cases (14.3%) and poor in 2 cases (9.5%). Immediate postoperative X-rays showed obvious improvements in lordosis and in the intervertebral height of the cervical spine (P<0.01). There is no evidence of instrument failure during the mean follow-up period of 14.2 months (9-24 months, P>0.01). Conclusion:Anterior cervical decompression in subsection, autograft fusion and internal fixation is a rational effective method for the surgical treatment of multilevel CSM.

  2. Clinical outcomes of lumbar degenerative disc disease treated with posterior lumbar interbody fusion allograft spacer: a prospective, multicenter trial with 2-year follow-up.

    Science.gov (United States)

    Arnold, Paul M; Robbins, Stephen; Paullus, Wayne; Faust, Stephen; Holt, Richard; McGuire, Robert

    2009-07-01

    The clinical benefits and complications of posterior lumbar interbody fusion (PLIF) have been studied over the past 60 years. In recent years, spine surgeons have had the option of treating low back pain caused by degenerative disc disease using PLIF with machined allograft spacers and posterior pedicle fixation. The purpose of this clinical series was to assess the clinical benefits of using a machined PLIF allograft spacer and posterior pedicle fixation to treat degenerative disc disease, both in terms of fusion rates and patient outcomes, and to compare these results with those in previous studies using autograft and metal interbody fusion devices. Results were also compared with results from studies using transverse process fusion. This prospective, nonrandomized clinical series was conducted at 10 US medical centers. Eighty-nine (55 male, 34 female) patients underwent PLIF with a presized, machined allograft spacer and posterior pedicle fixation between January 2000 and April 2003. Their outcomes were compared with outcomes in previous series described in the literature. All patients had experienced at least 6 months of low back pain that had been unresponsive to nonsurgical treatment. Physical examinations were performed before surgery, after surgery, and at 4 follow-up visits (6 weeks, 6 months, 12 months, 24 months). At each interval, we obtained radiographs and patient outcome measures, including SF-36 Bodily Pain Score, visual analog scale pain rating, and Oswestry Disability Index. The primary outcome was fusion results at 12 and 24 months; the secondary outcomes were pain, disability, function/quality of life, and satisfaction. One-level PLIFs were performed in 65 patients, and 2-level PLIFs in 24 patients. Flexion-extension radiographs at 12 and 24 months revealed a 98% fusion rate. Of the 72 patients who reached the 12-month follow-up, 86% reported decreased pain and disability as measured with the Oswestry Disability Index. Decreased pain as measured

  3. Structural analysis of the intervertebral discs adjacent to an interbody fusion using multibody dynamics and finite element cosimulation

    Energy Technology Data Exchange (ETDEWEB)

    Monteiro, Nuno Miguel Barroso, E-mail: nuno.barroso.monteiro@gmail.com; Silva, Miguel Pedro Tavares da, E-mail: MiguelSilva@ist.utl.pt; Folgado, Joao Orlando Marques Gameiro, E-mail: jfolgado@dem.ist.utl.pt [Technical University of Lisbon, IDMEC/IST-Instituto Superior Tecnico (Portugal); Melancia, Joao Pedro Levy, E-mail: levymelancia@netcabo.pt [University of Lisbon, FML-Faculdade de Medicina de Lisboa (Portugal)

    2011-02-15

    This work describes a methodology for the dynamic and structural analysis of complex (bio)mechanical systems that joins both multibody dynamics and finite element domains, in a synergetic way, through a cosimulation procedure that takes benefit of the advantages of each numerical formulation. To accomplish this goal, a cosimulation module is developed based on the gluing algorithm X-X, which is the key element responsible for the management of the information flux between the two software packages (each using its own mathematical formulation and code). The X-X algorithm uses for each cosimulated structure multiple pairs of reference points whose kinematics are solved by the multibody module and prescribed, as initial data, to the finite element counterpart. The finite element module, by its turn, solves the structural problem imposed by the prescribed kinematics, calculates the resulting generalized loads applied over the reference points and return these loads back to the multibody module that uses them to solve the dynamic problem and to calculate new reference kinematics to prescribe to the finite element module in the next time step. The proposed method is applied to study the cervical spine dynamics in a pathologic situation in which an intersomatic fusion is simulated to confirm its potential advantages. Taking into account the proposed simulation scenario, a cervical spine multibody model that includes the rigid vertebrae, the facet joints' and spinous processes' contacts, ligaments and the finite element models of the intervertebral discs, and their surrogates is developed. The proposed model is simulated for extension in a forward dynamics perspective.

  4. Clinical results of cervical laminectomy and fusion for the treatment of cervical spondylotic myelopathy in 58 consecutive patients

    Directory of Open Access Journals (Sweden)

    Victor Chang

    2014-01-01

    Conclusion: Cervical laminectomy and fusion is a safe and efficacious procedure for the treatment of CSM. The clinical outcomes appear to be quite reproducible, and this technique is an important part of a spine surgeon′s armamentarium.

  5. Biological properties of expandable bridge-arch interbody fusion cage%可膨胀桥拱式椎间融合器的生物学特性

    Institute of Scientific and Technical Information of China (English)

    李莹; 曾昭峰; 张春霖; 严旭

    2014-01-01

    背景:随着脊柱内窥镜等微创技术的发展,各种融合器尤其是膨胀式融合器成为一个研究热点。  目的:介绍自行研制的用于治疗腰椎退行性疾病新的“可膨胀桥拱式椎间融合器”的设计理念和生物学特性。方法:在万方数据库、中国生物医学数据库、中文科技期刊数据库中检索2000年1月至2011年4月有关融合器应用于腰椎退行性疾病的研究文章,关键词为“腰椎退行性疾病,融合器”。分析目前融合器存在的不足,从而提出一种治疗腰椎退行性疾病的新型融合器的构想。  结果与结论:经检索共查到相关文献50篇,排除筛选后纳入34篇进行评价。结合文献检索结果,提示了理想的膨胀式椎间融合器除体积小巧、便于植入等特性外,还应提供足够强度的椎体间支撑及稳定性,可有效防止植入后椎间隙高度丢失。参考以上条件,依据现有技术改良,研制出“可膨胀桥拱式椎间融合器”,十分便于微创植入,稳定性好,防下沉能力强,有很好的应用前景。%BACKGROUND:As spine endoscope and other microinvasive techniques develop, various fusion cages in particular expanded cage become the hot topic. OBJECTIVE:To introduce the design concept and biological characteristics of the novel expandable bridge-arch interbody fusion cage to treat lumbar degenerative disease. METHODS:A computer-based online search of Wanfang, CMB and VIP databases was performed for articles published between January 2000 and April 2011 related to the application of fusion cages in lumbar degenerative disease, with key words “lumbar degenerative disease, interbody fusion cage”. Insufficiency in present cages was analyzed and a novel cage should be designed. RESULTS AND CONCLUSION:A total of 50 relevant literatures were colected, and 27 were included. Results showed that ideal expandable cage should have smal size

  6. Multisegmental cervical ossification of the posterior longitudinal ligament: Anterior vs posterior approach

    OpenAIRE

    Jain Subodh; Salunke Pravin; Vyas K; Behari Sanjay; Banerji Deepu; Jain Vijendra

    2005-01-01

    Aims : To determine the surgical approach in patients with multisegmental (four or more segments) OPLL of the cervical spine. Methods and Materials : Data of 27 patients who had undergone either an anterior (corpectomy with excision of OPLL and interbody fusion=14 patients) or posterior approach (laminectomy=12, laminoplasty=1 patient) for the multisegmental cervical OPLL was analyzed retrospectively. The patients in each group were statistically similar in respect to preoperative factors su...

  7. Comparison of inpatient vs. outpatient anterior cervical discectomy and fusion: a retrospective case series

    OpenAIRE

    Friedman Jonathan A; Briner Rudy P; Liu Jeffrey T

    2009-01-01

    Abstract Background Spinal surgery is increasingly being done in the outpatient setting. We reviewed our experience with inpatient and outpatient single-level anterior cervical discectomy and fusion with plating (ACDF+P). Methods All patients undergoing single-level anterior cervical discectomy and fusion with plating between August 2005 and May 2007 by two surgeons (RPB or JAF) were retrospectively reviewed. All patients underwent anterior cervical microdiscectomy, arthrodesis using structur...

  8. 微创与开放后路腰椎间融合修复单节段腰椎退变性疾病:椎间融合率比较%Minimally invasiveversus open posterior lumbar interbody fusion for single-segment degenerative lumbar disease:the rate of interbody fusion

    Institute of Scientific and Technical Information of China (English)

    过锡敏

    2015-01-01

    BACKGROUND:With the aging population, the incidence of lumbar degenerative disease was apparently increased, but how to treatment of degenerative lumbar disease remains controversial. OBJECTIVE:To compare clinical and radiographic results of minimaly invasive posterior lumbar interbody fusion and open posterior lumbar interbody fusion for single-segment degenerative lumbar disease. METHODS: We retrospectively analyzed the clinical data of 97 patients with single-segment degenerative lumbar disease, who were treated in the Huishan District People’s Hospital of Wuxi City from July 2006 to July 2012. These patients were divided into minimal group (minimaly invasive posterior lumbar interbody fusion;n=51) and open group (open posterior lumbar interbody fusion;n=46). These data were compared between the two groups, including operative time, blood loss (intraoperative blood volume+postoperative drainage volume), total blood transfusion, postoperative back pain (visual analogue scale), length of hospital stay, bed time, perioperative complications, clinical function (Oswestry disability index), and radiographic results. RESULTS AND CONCLUSION:Al of 97 patients were folowed up. The duration of folow-up was 28-78 months and 27-76 months in minimal group and open group, respectively. There was no significant difference between the minimal group and open group in term of folowed-up time (P=0.981). Operative time, blood loss, total blood transfusion, bed time, length of hospital stay and visual analogue scale score during final folow-up were significantly lower in the minimal group than in the open group (P 0.05). These results indicate that for the single-segment degenerative lumbar disease, the use of minimaly invasive posterior lumbar interbody fusion or open posterior lumbar interbody fusion can obtain satisfactory clinical function, but the minimaly invasive posterior lumbar interbody fusion has the advantages of a less trauma, shorter length of hospital stay and bed

  9. Relationship of lumbar interbody fusion with anterior column structure and biomechanics%椎间植骨融合效果与腰椎前柱组织结构及生物力学的关系

    Institute of Scientific and Technical Information of China (English)

    谢鸿儒; 王欢

    2011-01-01

    BACKGROUND: Lumbar spine fusion is one of the most common operations for low back pain in spinal surgeons, but the clinicalspine fusion rate is still low-level. How to availably promote spine fusion, raise fusion rate and clinical effect, and decreasecomplications is a problem for the spinal surgeon to work out.OBJECTIVE: To summarize the relation between lumbar interbody fusion and anterior column, and to analyze the influence ofstructural and biomechanical changes on fusion rate.METHODS: A computer online retrieval of CBM/CNKI/Medline for articles and reviews about lumbar interbody fusion published1995-2009 was performed.RESULTS AND CONCLUSION: The stability and integrality of the anterior column have notable effects on interbody fusion. Inanterior lumbar interbody fusion and the fixations of anterior column fracture, we would better protect the structure and bloodsupply of the anterior column, and resume the integrality and stability of the anterior column to maintain the biomechanicsenvironment of the lumbar, aiming to achieve the better fusion effect.%背景:腰椎融合后,椎间植骨融合率低,是临床上亟待解决的问题.目的:阐述椎间植骨融合效果与腰椎前柱的关系,分析其组织结构及生物力学发生改变后对椎体间植骨融合效果的影响.方法:电子检索CBM/CNKI(2000/2010)和计算机Medline数据库(1995/2010)收录的腰椎椎间植骨融合的相关综述和论文报告,找出并分析其中与前柱结构及生物力学相关的研究进展.结果与结论:腰椎前柱的完整性及生物力学的稳定性对椎间植骨融合的效果有显著的影响.在腰椎前路间盘切除及腰椎前柱爆裂骨折撑开内固定中,应该着重保护好椎体前柱结构及血运,尽量恢复腰椎前柱结构的完整性及稳定性,维持腰椎正常的生物力学环境,以期达到理想的椎间融合效果.

  10. 微创经椎间孔腰椎椎体间融合术与传统后路腰椎椎体间融合术治疗腰椎退变性疾病的疗效及并发症比较%A comparative study on the curative effect and complications of minimally invasive transforaminal lumbar interbody fusion and tradi-tional posterior lumbar interbody fusion in treatment of lumbar degenerative disease

    Institute of Scientific and Technical Information of China (English)

    冯建宏; 辛欣

    2016-01-01

    Objective To compare the curative effect and complications of minimally invasive transforaminal lumbar interbody fusion and traditional posterior lumbar fusion in treatment of patients with lumbar degenerative disease. Methods The clinical data of 158 patients with lum-bar degenerative disease,including 83 cases by using traditional posterior lumbar interbody fusion as control group,and remaining 75 cases by u-sing minimally invasive transforaminal lumbar interbody fusion in observation group were retrospectively analyzed. The situations of therapeutic effect and complications in patients of these two groups had been compared. Results The amount of intraoperative blood loss and postoperative drainage in patients of observation group were better than those of patients in control group( P 0. 05). Conclusion The rates of efficay of minimally invasive transforaminal lumbar interbody fusion and tradi-tional posterior lumbar interbody fusion in treatment of patients with lumbar degenerative disease are similar,but the former has higher safety with less invasive,less blood loss,less drainage and less complications.%目的:比较微创经椎间孔腰椎椎体间融合术与传统后路腰椎椎体间融合术治疗腰椎退变性疾病的临床效果和并发症情况。方法回顾性分析158例腰椎退变性疾病患者的临床资料,其中83例行传统后路腰椎椎体间融合术设为对照组,余75例行微创经椎间孔腰椎椎体间融合术设为观察组;比较两组患者的治疗效果和并发症情况。结果观察组的术中出血量、术后引流量少于对照组( P 0.05)。结论微创经椎间孔腰椎椎体间融合术与传统后路腰椎椎体间融合术治疗腰椎退变性疾病的疗效类似,但前者手术损伤更小,出血量与引流量更少,神经损伤发生率更低,具有较高安全性。

  11. Comparison between anterior cervical discectomy with fusion and anterior cervical corpectomy with fusion for the treatment of cervical spondylotic myelopathy: a meta-analysis

    Directory of Open Access Journals (Sweden)

    Fei Q

    2015-11-01

    Full Text Available Qi Fei,* Jinjun Li,* Nan Su, Bingqiang Wang, Dong Li, Hai Meng, Qi Wang, Jisheng Lin, Zhao Ma, Yong Yang, Department of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China *These authors contributed equally to this work Background: Whether anterior cervical discectomy with fusion (ACDF or anterior cervical corpectomy with fusion (ACCF is superior in the treatment of cervical spondylotic myelopathy remains controversial. Therefore, we conducted a meta-analysis to quantitatively compare the efficacy and safety of ACDF and ACCF in the treatment of cervical spondylotic myelopathy.Methods: PubMed, Embase, Web of Science, SinoMed (Chinese BioMedical Literature Service System, People’s Republic of China, and CNKI (China National Knowledge Infrastructure, People’s Republic of China were systematically searched to identify all available studies comparing efficacy and safety between patients receiving ACDF and ACCF. The weighted mean difference (WMD was pooled to compare the Japanese Orthopaedic Association scores, visual analog scale scores, hospital stay, operation time, and blood loss. The risk ratio was pooled to compare the incidence of complications and fusion rate. Pooled estimates were calculated by using a fixed-effects model or a random-effects model according to the heterogeneity among studies.Results: Eighteen studies (17 observational studies and one randomized controlled trial were included in this meta-analysis. Our results suggest that hospital stay (WMD =-1.33, 95% confidence interval [CI]: -2.29, -0.27; P=0.014, operation time (WMD =-26.9, 95% CI: -46.13, -7.67; P=0.006, blood loss (WMD =-119.36, 95% CI: -166.94, -71.77; P=0.000, and incidence of complications (risk ratio =0.51, 95% CI: 0.33, 0.80; P=0.003 in the ACDF group were significantly less than that in the ACCF group. However, other clinical outcomes, including post-Japanese Orthopaedic Association score (WMD =-0.27, 95

  12. The significance of removing ruptured intervertebral discs for interbody fusion in treating thoracic or lumbar type B and C spinal injuries through a one-stage posterior approach.

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    Qian-Shi Zhang

    Full Text Available OBJECTIVES: To identify the negative effect on treatment results of reserving damaged intervertebral discs when treating type B and type C spinal fracture-dislocations through a one-stage posterior approach. METHODS: This is a retrospective review of 53 consecutive patients who were treated in our spine surgery center from January 2005 to May 2012 due to severe thoracolumbar spinal fracture-dislocation. The patients in Group A (24 patients underwent long-segment instrumentation laminectomy with pedicle screw-rod fixators for neural decompression. In Group B (29 patients, the patients underwent long-segment instrumentation laminectomy with pedicle screw-rod fixators for neural decompression evacuating of the ruptured disc and inserting of a bone graft into the evacuated disc space for interbody fusion. The mean time between injury and operation was 4.1 days (range 2-15 days. The clinical, radiologic and complication outcomes were analyzed retrospectively. RESULTS: Periodic follow-ups were carried out until an affirmative union or treatment failure took place. A progressive kyphosis angle larger than 10°, loss of disc height, pseudoarthrosis, recurrence of dislocation or subluxation, or instrument failure before fusion were considered treatment failures. Treatment failures were detected in 13 cases in Group A (failure rate was 54.2%. In Group B, there were 28 cases in which definitive bone fusion was demonstrated on CT scans, and CT scans of the other cases demonstrated undefined pseudoarthrosis without hardware failure. There were statistically significant differences between the two groups (p0.05 Fisher's exact test. CONCLUSION: Intervertebral disc damage is a common characteristic in type B and C spinal fracture-dislocation injuries. The damaged intervertebral disc should be removed and substituted with a bone graft because reserving the damaged disc in situ increases the risk of treatment failure.

  13. Novel pedicle screw and plate system provides superior stability in unilateral fixation for minimally invasive transforaminal lumbar interbody fusion: an in vitro biomechanical study.

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    Jie Li

    Full Text Available This study aims to compare the biomechanical properties of the novel pedicle screw and plate system with the traditional rod system in asymmetrical posterior stabilization for minimally invasive transforaminal lumbar interbody fusion (MI-TLIF. We compared the immediate stabilizing effects of fusion segment and the strain distribution on the vertebral body.Seven fresh calf lumbar spines (L3-L6 were tested. Flexion/extension, lateral bending, and axial rotation were induced by pure moments of ± 5.0 Nm and the range of motion (ROM was recorded. Strain gauges were instrumented at L4 and L5 vertebral body to record the strain distribution under flexion and lateral bending (LB. After intact kinematic analysis, a right sided TLIF was performed at L4-L5. Then each specimen was tested for the following constructs: unilateral pedicle screw and rod (UR; unilateral pedicle screw and plate (UP; UR and transfacet pedicle screw (TFS; UP and TFS; UP and UR.All instrumented constructs significantly reduced ROM in all motion compared with the intact specimen, except the UR construct in axial rotation. Unilateral fixation (UR or UP reduced ROM less compared with the bilateral fixation (UP/UR+TFS, UP+UR. The plate system resulted in more reduction in ROM compared with the rod system, especially in axial rotation. UP construct provided more stability in axial rotation compared with UR construct. The strain distribution on the left and right side of L4 vertebral body was significantly different from UR and UR+TFS construct under flexion motion. The strain distribution on L4 vertebral body was significantly influenced by different fixation constructs.The novel plate could provide sufficient segmental stability in axial rotation. The UR construct exhibits weak stability and asymmetrical strain distribution in fusion segment, while the UP construct is a good alternative choice for unilateral posterior fixation of MI-TLIF.

  14. Hybrid Surgery Versus Anterior Cervical Discectomy and Fusion in Multilevel Cervical Disc Diseases: A Meta-Analysis.

    Science.gov (United States)

    Zhang, Jianfeng; Meng, Fanxin; Ding, Yan; Li, Jie; Han, Jian; Zhang, Xintao; Dong, Wei

    2016-05-01

    To investigate the outcomes and reliability of hybrid surgery (HS) versus anterior cervical discectomy and fusion (ACDF) for the treatment of multilevel cervical spondylosis and disc diseases.Hybrid surgery, combining cervical disc arthroplasty (CDA) with fusion, is a novel treatment to multilevel cervical degenerated disc disease in recent years. However, the effect and reliability of HS are still unclear compared with ACDF.To investigate the studies of HS versus ACDF in patients with multilevel cervical disease, electronic databases (Medline, Embase, Pubmed, Cochrane library, and Cochrane Central Register of Controlled Trials) were searched. Studies were included when they compared HS with ACDF and reported at least one of the following outcomes: functionality, neck pain, arm pain, cervical range of motion (ROM), quality of life, and incidence of complications. No language restrictions were used. Two authors independently assessed the methodological quality of included studies and extracted the relevant data.Seven clinical controlled trials were included in this study. Two trials were prospective and the other 5 were retrospective. The results of the meta-analysis indicated that HS achieved better recovery of NDI score (P = 0.038) and similar recovery of VAS score (P = 0.058) compared with ACDF at 2 years follow-up. Moreover, the total cervical ROM (C2-C7) after HS was preserved significantly more than the cervical ROM after ACDF (P = 0.000) at 2 years follow-up. Notably, the compensatory increase of the ROM of superior and inferior adjacent segments was significant in ACDF groups at 2-year follow-up (P multilevel cervical spondylosis to preserve cervical ROM and reduce the risk of adjacent disc degeneration. Nonetheless, more well-designed studies with large groups of patients are required to provide further evidence for the benefit and reliability of HS for the treatment of cervical disk diseases.

  15. MIS-TLIF与PLIF治疗单节段退行性腰椎疾病的疗效比较%Curative effect of minimally invasive surgery transforaminal lumbar interbody fusion and posterior lumbar interbody fusion on single segment degenerative lumbar diseases

    Institute of Scientific and Technical Information of China (English)

    周亮; 刘郑生; 肖嵩华; 毛克亚; 刘建恒; 史腾; 苏祥正

    2013-01-01

    目的:探讨扩张通道管系统(X-tube)辅助微创经椎间孔路腰椎椎体间融合术(minimally invasive surgery transforaminal lumbar interbody fusion,MIS-TLIF)治疗退行性腰椎疾患的疗效。方法回顾性分析2010年10月-2011年9月我科采用X-Tube辅助MIS-TLIF治疗的单节段退行性腰椎病变患者52例,统计术前1 d、术后3 d、5 d、3个月、6个月、1年腰背痛和下肢痛视觉模拟评分(visual analogue scores,VAS),术前1 d、术后3个月、6个月、1年Oswestry功能障碍指数(Oswestry disability index,ODI),术后1年Nakai疗效评级和Bridwell脊柱融合评级,并与同期行传统开放后路腰椎椎体间融合术(posterior lumbar interbody fusion,PLIF)的38例患者进行比较。结果两组一般资料比较,差异均无统计学意义(P>0.05);术后3 d、5 d、3个月,微创组腰背痛VAS评分低于开放组(P<0.05,其中术后3 d、5 d,P<0.01);其余时间两组间腰背痛和下肢痛VAS评分、ODI评分无统计学差异(P>0.05);两组术后1年Nalai疗效评级和Bridwell脊柱融合评级差异无统计学意义(P>0.05)。结论在治疗退行性腰椎疾病时,MIS-TLIF术式可获得与传统开放PLIF术式相当的治疗效果,且术后短期内腰背痛程度较低。%Objective To study the curative effect of X-tube system-assisted minimally invasive surgery transforaminal lumbar interbody fusion (MIS-TLIF) on degenerative lumbar diseases.Methods Clinical data about 52 patients with single segment degenerative lumbar disease who underwent MIS-TLIF from October 2010 to September 2011 in our hospital were retrospectively analyzed. Their visual analogue score (VAS) of back and leg pain 3 and 5 days, 3 and 6 months, and 1 year after MIS-TLIF, their Oswestry disability index (ODI) 1 day, 3 and 6 months, and 1 year after MIS-TLIF, their Nakai curative effect and Bridwell spinal fusion classification were compared with those of 38 controls after

  16. Laryngeal dislocation after ventral fusion of the cervical spine

    Directory of Open Access Journals (Sweden)

    Jenny Krauel

    2013-01-01

    Full Text Available We report on a 70-year-old patient who underwent ventral fusion of the cervical spine (C3/4 and C4/5 for spinal canal stenosis performed by the neurosurgery department. The patient suffered an exceedingly rare complication of the surgery - laryngeal dislocation. Had the deformed laryngeal structures been overlooked and the patient extubated as usual after surgery, reintubation would have been impossible due to the associated swelling, which might have had disastrous consequences. Leftward dislocation of the larynx became apparent post-operatively, but prior to extubation. Extubation was therefore postponed and a subsequent computed tomography (CT scan revealed entrapment of laryngeal structures within the osteosynthesis. A trial of repositioning using microlaryngoscopy performed by otolaryngology (ears, nose and throat specialists failed, making open surgical revision necessary. At surgery, the entrapped laryngeal tissue was successfully mobilised. Laryngeal oedema developed despite prompt repositioning; thus, necessitating tracheotomy and long-term ventilation. Laryngeal dislocation may be an unusual cause of post-operative neck swelling after anterior cervical spine surgery and should be considered in the differential diagnosis if surgical site haematoma and other causes have been ruled out. Imaging studies including CT of the neck may be needed before extubation to confirm the suspicion and should be promptly obtained to facilitate specific treatment.

  17. Comparison of simple discectomy and instrumented posterior lumbar interbody fusion for treatment of lumbar disc herniation combined with Modic endplate changes

    Institute of Scientific and Technical Information of China (English)

    Cao Peng; Chen Zhe; Zheng Yuehuan; Wang Yuren; Jiang Leisheng; Yang Yaoqi; Zhuang Chengyu

    2014-01-01

    Background The purpose of this retrospective study was to compare the surgical outcomes of simple discectomy and instrumented posterior lumbar interbody fusion (iPLIF) in patients with lumbar disc herniation and Modic endplate changes.Our hypothesis was that iPLIF could provide better outcome for patients with refractory lumbar disc herniation and Modic changes (LDH-MC).Methods Ninety-one patients with single-segment LDH-MC were recruited.All patients experienced low back pain as well as radicular leg pain,and low back pain was more severe than leg pain.Forty-seven patients were treated with discectomy and 44 were treated with iPLIE The outcomes of both low back pain and radicular leg pain using visual analogue scale (VAS) as well as the clinical outcome related to low back pain using Japanese Orthopaedic Association (JOA) score were assessed before and 18 months after surgery,respectively.Results Both low back and leg pain were significantly improved 18 months after simple discectomy and iPLIE Compared to patients undergoing simple discectomy,low back pain was significantly reduced in patients undergoing iPLIE but there was no significant difference in leg pain between two groups.Solid fusion was achieved in all patients who underwent iPLIF.Conclusions In patients with LDH-MC,iPLIF can yield significantly superior outcome on the relief of low back pain compared to simple discectomy.Simple discectomy can relieve radicular leg pain as efficient as iPLIE Accordingly,iPLIF seems to be a reliable treatment for patients with LDH-MC and predominant low back pain.

  18. 微创经椎间孔腰椎椎体间融合术研究进展%Research Progress of Minimally Invasive Transforaminal Lumbar Interbody Fusion

    Institute of Scientific and Technical Information of China (English)

    张锋

    2013-01-01

    Lumbar fusion is currently the major treatment of lumbar degenerative disease( spondylosis, spinal instability and discogenic disease etc. ). Transforaminal lumbar interbody fusion ( TLIF )has become increasingly popular in recent years. Compared with PLIF,TLIF requires less neural manipulation and retraction, thus reduces interference to the nerve root and dural sac. With the fast development of minimally invasive spine surgery,minimally invasive TLIF has been widely applied in clinical. Here is to make a review of the indicationsand contraindications,surgical method,advantages and disadvantages of minimally invasive TLIF.%腰椎退变性疾病(腰椎滑脱、退变性腰椎失稳、椎间盘源性疾病等)常须行腰椎椎间融合术,近年来经椎间孔入路的腰椎间融合术(TLIF)得到了充分的发展,与传统的后路腰椎间融合手术相比,TLIF对神经根及硬模囊的干扰较少,从而减少了相关并发症的发生.随着微创脊柱外科的进步,微创TLIF也越来越广泛地应用于临床.该文对微创经椎间孔腰椎椎体间融合术的适应证与禁忌证、手术方式、优势与不足、问题与展望等方面的研究现状予以综述.

  19. 微创经椎间孔腰椎椎体间融合术的研究进展%Research progress of minimally invasive transforaminal lumbar interbody fusion

    Institute of Scientific and Technical Information of China (English)

    潘杰; 钱列; 谭军

    2009-01-01

    腰椎融合是目前治疗腰椎退变性疾病、腰椎不稳及椎间盘源性等疾病的主要手段.经椎间孔腰椎间融合术(transforaminal lumbar interbody fusion,TLIF)是近年发展起来的新型的腰椎融合术,而随着微创脊柱外科(minimally invasive spinal surgery,MISS)的进步,微创TLIF技术也得到了快速的发展,相对传统开放TLIF又有了更进一步的优势.作者就微创TLIF的适应证与禁忌证,手术方式,发展与优势及微创手术辅助器械等方面的研究现状作一综述.%Lumbar fusion is currently the major treatment of lumbar degenerative disease, spinal instability and discogenic disease etc. Transforaminal lumbar interbody fusion (TLIF) is a novel lumbar fusion technique in recent years, and with the progress of minimally invasive spinal surgery, minimally invasive TLIF (mini-TLIF) technique has also got access to rapid development, which has more advantages compared with traditional open TLIF. The authors review the indications and contraindications, surgical method, development and advantages and minimally invasive surgical assistant instruments of mini -TLIF.

  20. Clinical application of anterior cervical decompression and fusion under METRx system

    Institute of Scientific and Technical Information of China (English)

    ZHOU Yue; ZHANG Xia; WANG Wei-dong; LI Chang-qing; CHU Tong-wei; ZHANG Zheng-feng; WANG Jian; ZHENG Wen-jie

    2005-01-01

    Objective: To explore the feasibility and effect of anterior cervical decompression and fusion under METRx system. Methods: Between Nov. 2001 and Nov. 2003, totally 23 consecutive patients were performed anterior cervical decompression and fusion under METRx system. The clinical outcome was evaluated by Odom standard. Results: Decompression and fusion along with internal fixation was obtained in all the 23 patients with minimal tissue damage and operation-caused scar. There were no wound infection, neurological injuries, throat discomfort and other complications. The total rate of excellent and good outcome in patients with degenerative cervical diseases was 94%. Conclusion: Cervical decompression and fusion can be performed under METRx system with its own advantages, such as minimal tissue damage and operation-caused scar, less throat discomfort.

  1. Anterior Cervical Corpectomy and Fusion Accelerates Degenerative Disease at Adjacent Vertebral Segments

    OpenAIRE

    Pickett, Gwynedd E.; Duggal, Neil; Theodore, Nicholas; Sonntag, Volker K.H.

    2008-01-01

    Background Anterior cervical corpectomy provides the most direct and thorough surgical approach for anterior decompression when spinal cord compression is found directly behind the vertebral body. However, anterior cervical fusion has been shown to be associated with the development of new degenerative changes at levels immediately adjacent to the fused segments. Th e incidence of adjacent segment disease (ASD) following anterior cervical corpectomy has not been widely reported. We set out to...

  2. Comparison of adjacent segment degeneration five years after single level cervical fusion and cervical arthroplasty:a retrospective controlled study

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    SUN Yu; ZHAO Yan-bin; PAN Sheng-fa; ZHOU Fei-fei; CHEN Zhong-qiang; LIU Zhong-jun

    2012-01-01

    Background Cervical arthroplasty is indicated to preserve cervical motion and prevent accelerated adjacent segment degeneration.Whether accelerated adjacent segment degeneration is prevented in the long term is unclear.This trial compared adjacent segment degeneration in Bryan disc arthroplasty with that in anterior cervical decompression and fusion five years after the surgery.Methods We studied patients with single level degenerative cervical disc disease.The extent of adjacent segment degeneration was estimated from lateral X-rays.Results Twenty-six patients underwent single level Bryan disc arthroplasty and twenty-four patients underwent single level anterior cervical decompression and fusion.All patients were followed up for an average of sixty months.In the Bryan arthroplasty group,nine(17.6%)segments developed adjacent segment degeneration,which was significantly lower than that(60.4%)in the anterior cervical decompression and fusion group.Eleven segments in the Bryan arthroplasty group developed heterotopic ossification according to McAfee's classification and two segments had range of motion less than 2°.In the heterotopic ossification group,four(19.5%)segments developed adjacent segment degeneration,similar to the number in the non-heterotopic ossification group(16.7%).Adjacent segment degeneration rate was 50% in gradeⅣ?group but 11.8% in gradeⅡ?to Ⅲ.Conclusions Adjacent segment degeneration was accelerated after anterior cervical decompression and fusion.However,Bryan disc arthroplasty avoided accelerated adjacent segment degeneration by preserving motion.Patients with gradeⅣ?heterotopic ossification lost motion,and the rate of adjacent segment degeneration was higher than that in patients without heterotopic ossification.

  3. Total Disc Arthroplasty and Anterior Cervical Discectomy and Fusion in Cervical Spine: Competitive or Complimentary? Review of the Literature

    OpenAIRE

    Jawahar, Ajay; Nunley, Pierce

    2012-01-01

    Anterior cervical discectomy and arthrodesis has come to represent standard of care for patients with persistent radicular and/or myelopathic symptoms that have failed to improve with conservative treatments. One potential complication of the procedure is the accelerated degeneration of the vertebrae and the intervertebral discs adjacent to the level fused and the effects of fusion on those levels. The concern that fusion may be a contributing factor to accelerated adjacent segment degenerati...

  4. Hybrid Surgery Versus Anterior Cervical Discectomy and Fusion in Multilevel Cervical Disc Diseases: A Meta-Analysis.

    Science.gov (United States)

    Zhang, Jianfeng; Meng, Fanxin; Ding, Yan; Li, Jie; Han, Jian; Zhang, Xintao; Dong, Wei

    2016-05-01

    To investigate the outcomes and reliability of hybrid surgery (HS) versus anterior cervical discectomy and fusion (ACDF) for the treatment of multilevel cervical spondylosis and disc diseases.Hybrid surgery, combining cervical disc arthroplasty (CDA) with fusion, is a novel treatment to multilevel cervical degenerated disc disease in recent years. However, the effect and reliability of HS are still unclear compared with ACDF.To investigate the studies of HS versus ACDF in patients with multilevel cervical disease, electronic databases (Medline, Embase, Pubmed, Cochrane library, and Cochrane Central Register of Controlled Trials) were searched. Studies were included when they compared HS with ACDF and reported at least one of the following outcomes: functionality, neck pain, arm pain, cervical range of motion (ROM), quality of life, and incidence of complications. No language restrictions were used. Two authors independently assessed the methodological quality of included studies and extracted the relevant data.Seven clinical controlled trials were included in this study. Two trials were prospective and the other 5 were retrospective. The results of the meta-analysis indicated that HS achieved better recovery of NDI score (P = 0.038) and similar recovery of VAS score (P = 0.058) compared with ACDF at 2 years follow-up. Moreover, the total cervical ROM (C2-C7) after HS was preserved significantly more than the cervical ROM after ACDF (P = 0.000) at 2 years follow-up. Notably, the compensatory increase of the ROM of superior and inferior adjacent segments was significant in ACDF groups at 2-year follow-up (P benefit and reliability of HS for the treatment of cervical disk diseases. PMID:27227922

  5. Postoperative Cervical Haematoma Complicated by Ipsilateral Carotid Thrombosis and Aphasia after Anterior Cervical Fusion: A Case Report

    Directory of Open Access Journals (Sweden)

    Kingsley R. Chin

    2013-01-01

    Full Text Available Hematoma alone is the most common vascular complication reported after anterior cervical decompression and fusion (ACDF. We present this case to report the occurrence of postoperative cervical hematoma complicated by ipsilateral carotid thrombosis and aphasia after an uncomplicated C4–6 ACDF. This is a case of a 65-year-old woman who underwent revision fusions of the C4-5 and C6-7 levels complicated by postoperative cervical hematoma and carotid thrombosis. The patient's history, clinical examination, imaging findings, and treatment are reported. The revision fusions were performed and deemed routine. Approximately eight hours later 200 mL of blood was evacuated from a postoperative cervical hematoma. The patient became unresponsive and disoriented a few hours after evacuating the hematoma. Computed tomography and magnetic resonance imaging of the brain were normal, but magnetic resonance angiography demonstrated total occlusion of the left carotid artery. Thrombectomy was performed and the patient was discharged without residual deficits. At the latest followup she is fully functional and asymptomatic in her neck. We suggest, after evacuating a cervical hematoma, an evaluation of the carotids be made with MRA or cerebral angiography, as this may demonstrate a clot before the patient develops symptoms.

  6. Minimally invasive versusopen transforaminal lumbar interbody fusion for lumbar degenerative disease:a meta-analysis%微小切口与经椎间孔腰椎融合治疗腰椎退行性病的Meta分析

    Institute of Scientific and Technical Information of China (English)

    冉兵; 严磊; 赵晓蕾; 谢远龙; 蔡林

    2014-01-01

    背景:大量研究已证实微小切口与开放经椎间孔腰椎椎间融合治疗单节段和多节段腰椎退行性疾病均有较好的疗效,但两种治疗方法的优劣目前尚无定论。  目的:系统评价微小切口与开放经椎间孔腰椎椎间融合治疗腰椎退行性疾病的疗效及安全性。  方法:计算机检索 The Cochrane Library(2014年第2期)、PubMed、EMbase、MEDLINE、SCI、CNKI、CBM、WanFang Data,检索时限为到2014年2月;收集采用微小切口与开放经椎间孔腰椎椎间融合治疗腰椎退行性疾病的随机或非随机同期对照试验。由2名评价者按照纳入与排除标准选择试验、提取资料和评价质量后,采用RevMan 5.2软件进行Meta分析。  结果与结论:纳入1个随机对照试验,18个非随机对照试验,共1400例患者。Meta分析结果显示,与传统开放经椎间孔腰椎椎间融合相比,微小切口经椎间孔腰椎椎间融合具有椎旁肌损伤小,出血量少,住院时间短,早期疗效好,腰痛远期缓解率高等优点;但是微小切口经椎间孔腰椎椎间融合在改善远期运动功能,远期腿痛缓解率,减少并发症方面并不优于开放经椎间孔腰椎椎间融合治疗;且手术时间更长。因此,在严格掌握适应证的前提下,采用微小切口经椎间孔腰椎椎间融合能较好解决腰椎退行性疾病患者的病痛。由于纳入研究数量和质量存在局限性,上述结论仍需大样本、高质量的随机对照试验进一步验证。临床应根据患者的具体情况,综合评估病情,选择最佳治疗方案。%BACKGROUND:A large number of studies have confirmed that minimaly invasive and open transforaminal lumbar interbody fusion approaches for single-segment and multi-segment lumbar degenerative diseases were effective, but their advantages and disadvantages remain inconclusive. OBJECTIVE:To systematicaly evaluate the effectiveness

  7. Biomechanics of Hybrid Anterior Cervical Fusion and Artificial Disc Replacement in 3-Level Constructs: An In Vitro Investigation

    OpenAIRE

    Liao, Zhenhua; Fogel, Guy R.; Pu, Ting; Gu, Hongsheng; Liu, Weiqiang

    2015-01-01

    Background The ideal surgical approach for cervical disk disease remains controversial, especially for multilevel cervical disease. The purpose of this study was to investigate the biomechanics of the cervical spine after 3-level hybrid surgery compared with 3-level anterior cervical discectomy and fusion (ACDF). Material/Methods Eighteen human cadaveric spines (C2-T1) were evaluated under displacement-input protocol. After intact testing, a simulated hybrid construct or fusion construct was ...

  8. Different bone graft fusion materials applied in lumbar interbody fusion%不同植骨融合材料在腰椎椎体间脊柱融合中的应用

    Institute of Scientific and Technical Information of China (English)

    覃建朴; 王翀; 张朋云; 曹广如; 蔡玉强; 廖文波

    2016-01-01

    背景:脊柱融合治疗时选择合适的替代移植骨具有重要的意义,能够解决自体骨移植及其他移植材料带来的弊端。目的:观察不同植骨融合材料性能,探讨不同植骨融合材料在犬腰椎椎体间脊柱融合中的应用效果。方法:选取45只中华田园犬建立腰椎椎体间脊柱融合模型,建模后随机分3组,分别植入自体髂骨、重组人骨形态发生蛋白2复合材料和同种异体髂骨,分析不同植骨融合材料在犬腰椎椎体间脊柱融合中的效果。结果与结论:①融合率:重组人骨形态发生蛋白2复合材料组犬融合率显著高于其他组(P <0.05);②Oswestry 功能障碍指数:重组人骨形态发生蛋白2复合材料组术后 Oswestry 功能障碍指数显著低于其他2组(P <0.05);②组织学形态:苏木精-伊红染色显示,术后12周,与其他2组相比,重组人骨形态发生蛋白2犬完全骨性融合,且形成了连续骨小梁,植入骨与犬上下椎体完全粘连;④结果提示:重组人骨形态发生蛋白2复合材料更能够促更好地促进脊柱愈合,效果优于自体和同种异体骨移植。%BACKGROUND: The choice of suitable bone graft substitute is vital for spinal fusion treatment, which can solve some limitations caused by autogenous bone graft and other materials. OBJECTIVE: To investigate properties of different bone graft fusion materials, and to explore their application in dog spinal fusion of lumbar vertebral body. METHODS: Forty-five Chinese rural dogs were enrol ed to prepare lumbar interbody fusion models, and then were randomized into three groups transplanted with autogenous ilium, recombinant human bone morphogenetic protein-2 composite or al ograft ilium, respectively. Afterwards, effects of different materials in the lumbar interbody fusion were analyzed. RESULTS AND CONCLUSION: The fusion rate of the composite group was significantly higher than those of the other

  9. Spheno-Occipital Synchondrosis Fusion Correlates with Cervical Vertebrae Maturation

    Science.gov (United States)

    Fernández-Pérez, María José; McNamara, James A.; Velasco-Torres, Miguel; Benavides, Erika; Galindo-Moreno, Pablo; Catena, Andrés

    2016-01-01

    The aim of this study was to determine the relationship between the closure stage of the spheno-occipital synchondrosis and the maturational stage of the cervical vertebrae (CVM) in growing and young adult subjects using cone beam computed tomography (CBCT). CBCT images with an extended field of view obtained from 315 participants (148 females and 167 males; mean age 15.6 ±7.3 years; range 6 to 23 years) were analyzed. The fusion status of the synchondrosis was determined using a five-stage scoring system; the vertebral maturational status was evaluated using a six-stage stratification (CVM method). Ordinal regression was used to study the ability of the synchondrosis stage to predict the vertebral maturation stage. Vertebrae and synchondrosis had a strong significant correlation (r = 0.89) that essential was similar for females (r = 0.88) and males (r = 0.89). CVM stage could be accurately predicted from synchondrosis stage by ordinal regression models. Prediction equations of the vertebral stage using synchondrosis stage, sex and biological age as predictors were developed. Thus this investigation demonstrated that the stage of spheno-occipital synchondrosis, as determined in CBCT images, is a reasonable indicator of growth maturation. PMID:27513752

  10. Treatment of cervical dislocation with locked facets

    Institute of Scientific and Technical Information of China (English)

    YU Ze-sheng; James J.Yue; WEI Feng; LIU Zhong-jun; CHEN Zhong-qiang; DANG Geng-ting

    2007-01-01

    Background Lower cervical dislocation with locked facets is common in cervical injury. The locked facets include unilateral and bilateral types. Different successful closed reduction rates has been achieved between unilateral and bilateral types by using rapid skull traction, which was commonly used to reduce the cervical dislocation. It is important to investigate a suitable management specific to patients with different types of cervical locked facets.Methods A total of 38 patients with cervical dislocation with locked facet due to cervical injury treated by rapid skull traction and operation from 1988 to 2005 were reviewed. Rapid skull traction was used in all the patients. Successful closed reduction rate was 88.0% in patients with bilateral cervical locked facets and that was 15.4% in those with unilateral cervical locked facets. These data were then statistically compared by Chi-square test. Patients who were reduced successfully underwent anterior cervical discectomy and fusion at the injured level, and those who failed in closed reduction received posterior open reduction and fixation.Results In this series, there was statistically significant difference (P<0.05) in the rate of successful closed skull traction reduction between unilateral and bilateral locked facets dislocation. Unilateral cervical locked facets dislocation was not easily reduced by skull traction which was suitable for reduction of bilateral cervical locked facets dislocation. However,unilateral cervical locked facets dislocation can be reduced by posterior open reduction.Conclusions Unilateral cervical locked facets dislocation should be treated immediately with posterior open reduction and instrumentation. Bilateral cervical locked facets dislocation can be reduced by rapid skull traction firstly and anterior cervical discectomy and interbody fusion later.

  11. Clinical results and intramedullary signal changes of posterior decompression with transforaminal interbody fusion for thoracic myelopathy caused by combined ossification of the posterior longitudinal ligament and ligamentum flavum

    Institute of Scientific and Technical Information of China (English)

    WANG Lin-feng; LIU Fa-jing; ZHANG Ying-ze; SHEN Yong; DING Wen-yuan; XU Jia-xin

    2013-01-01

    Background Surgical treatment of thoracic myelopathy caused by ossification of the posterior longitudinal ligament (OPLL) and ossification of the ligamentum flavum (OLF) is technically demanding,and the results tend to be unfavorable.Various operative approaches and treatment strategies have been attempted,and posterior decompression with transforaminal thoracic interbody fusion (PTTIF) may be the optimal method with which the anterior-posterior compression was removed in one step.It is comparatively less traumatic with fewer serious complications.Methods Sixteen patients with thoracic myelopathy due to concurrent OLF and OPLL at the same level underwent PTTIF.We investigated clinical outcomes and neurological improvements.Magnetic resonance imaging (MRI) was performed on all patients preoperatively and postoperatively,and intramedullary signal changes were evaluated.Results The mean operating time was 275 minutes,and the mean operative bleeding amount was 1031 ml.Cerebrospinal fluid leakage occurred in three patients and healed well after repair.Neurological symptom deterioration occurred in one patient,but the patient recovered to nearly the preoperative level after methylprednisolone treatment.The follow-up period ranged from 28 to 47 months.The mean score on the Japanese Orthopedic Association scale improved from 4.3±1.2 preoperatively to 7.3±1.7 at 3 months postoperatively to 8.5±1.5 at the final follow-up (P <0.01),with a recovery rate of (63.6±20.0)%.Postoperative images showed a significant improvement in local kyphosis (P <0.01).Eleven patients (68.8%) showed increased signal intensity (ISI) on preoperative T2-weighted MRI.At the final follow-up,the intramedullary ISI totally recovered in five patients.Neurological improvement was worse in patients with persistent ISI than in the other patients (P <0.05).Conclusions PTTIF is an effective therapeutic option for combined OPLL and OLF and provides satisfactory neurological recovery and

  12. Dynamic stabilization for L4-5 spondylolisthesis: comparison with minimally invasive transforaminal lumbar interbody fusion with more than 2 years of follow-up.

    Science.gov (United States)

    Kuo, Chao-Hung; Chang, Peng-Yuan; Wu, Jau-Ching; Chang, Hsuan-Kan; Fay, Li-Yu; Tu, Tsung-Hsi; Cheng, Henrich; Huang, Wen-Cheng

    2016-01-01

    OBJECTIVE In the past decade, dynamic stabilization has been an emerging option of surgical treatment for lumbar spondylosis. However, the application of this dynamic construct for mild spondylolisthesis and its clinical outcomes remain uncertain. This study aimed to compare the outcomes of Dynesys dynamic stabilization (DDS) with minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) for the management of single-level spondylolisthesis at L4-5. METHODS This study retrospectively reviewed 91 consecutive patients with Meyerding Grade I spondylolisthesis at L4-5 who were managed with surgery. Patients were divided into 2 groups: DDS and MI-TLIF. The DDS group was composed of patients who underwent standard laminectomy and the DDS system. The MI-TLIF group was composed of patients who underwent MI-TLIF. Clinical outcomes were evaluated by visual analog scale for back and leg pain, Oswestry Disability Index, and Japanese Orthopaedic Association scores at each time point of evaluation. Evaluations included radiographs and CT scans for every patient for 2 years after surgery. RESULTS A total of 86 patients with L4-5 spondylolisthesis completed the follow-up of more than 2 years and were included in the analysis (follow-up rate of 94.5%). There were 64 patients in the DDS group and 22 patients in the MI-TLIF group, and the overall mean follow-up was 32.7 months. Between the 2 groups, there were no differences in demographic data (e.g., age, sex, and body mass index) or preoperative clinical evaluations (e.g., visual analog scale back and leg pain, Oswestry Disability Index, and Japanese Orthopaedic Association scores). The mean estimated blood loss of the MI-TLIF group was lower, whereas the operation time was longer compared with the DDS group (both p lumbar spondylolisthesis. However, unlike fusion, dynamic implants have issues of wearing and loosening in the long term. Thus, the comparable results between the 2 groups in this study require longer follow

  13. Minimally invasive transforaminal lumbar interbody fusion or posterior lumbar interbody fusion in treatment of lumbar degenerative disorder disease%椎间盘镜辅助X-Tube下椎体间融合术治疗退变性腰椎间盘疾病

    Institute of Scientific and Technical Information of China (English)

    马维虎; 刘观燚; 徐荣明; 孙韶华; 赵刘军; 胡勇; 蒋伟宇; 顾永杰

    2011-01-01

    目的 探讨椎间盘镜辅助X-Tube下腰椎后路椎体间融合术(posterior lumbar interbody fusion,PLIF)和经椎间孔腰椎椎体间融合术(transforaminal lumbar interbody fusion,TLIF)治疗退变性椎间盘疾病的临床疗效.方法 2007年11月至2008年4月,采用椎间盘镜辅助X-Tube下TLIF和PLIF 治疗退变性椎间盘疾病32例:PLIF 13例,TLIF 19例.单节段腰椎间盘突出症伴相应节段腰椎不稳定21例,腰椎滑脱症11例(Ⅰ度6例,Ⅱ度5例).病变节段:L3-4 2例,L4-5 18例,L5S1 12例.年龄38~72岁,平均51.2岁;男19例,女13例.术后进行定期随访和影像学检查,并进行Oswestry功能障碍指数评定以评价术后康复情况.结果 手术时间90~180 min,平均120 min;手术出血量100~400 ml,平均190ml.切口均为甲级愈合,未见切口及椎管、椎间隙感染、内固定失败等并发症发生.所以患者均获随访,随访时间13~41个月,平均21个月.Oswestry功能障碍指数由术前40.1%±4.1%下降到术后3个月的9.5%±3.7%.疗效评价:优19例,良10例,可3例;优良率为90.6%.骨融合均取得成功.结论 椎间盘镜辅助X-Tube下TLIF和PLIF治疗退变性椎间盘疾病具有切口小,创伤小,术后恢复快等优点.%Objective To evaluate the clinical effects of transforaminal lumbar interbody fusion (TLIF) or posterior lumbar interbody fusion(PLIF) using microendoscopic discectomy under X-Tube system in treatment of lumbar degenerative disc diseases.Methods From December 2007 to April 2008,32 patients with low back disorders were treated by microendoscopic discectomy TLIF or PLIF under X-Tube system,including 19 cases in TLIF and 13 in PLIF.Etiologies including lumbar disc herniation combined with segmental instability in 21 cases,and spondylolisthesis in 11 cases.All patients were under regular postoperative follow-up and radiological examination.The clinical functional outcomes were evaluated according to Oswestry disability questionnaire.Results The

  14. Tantalum trabecular metal implants in anterior cervical corpectomy and fusion: 2-year prospective analysis.

    Science.gov (United States)

    King, V; Swart, A; Winder, M J

    2016-10-01

    Anterior cervical decompression for two or more cervical spondylotic levels can be performed using either multiple anterior cervical discectomies and fusion or anterior cervical corpectomy and fusion (ACCF). A variety of options for ACCF implants exist but to our knowledge, there is no clinical data for the use of tantalum trabecular metal implants (TTMI) for ACCF. A retrospective review was performed of prospectively collected data for ten patients undergoing ACCF with TTMI between 2011 and 2012. Radiological outcome was assessed by measuring the change in cervical (C) lordosis (fusion Cobb and C2-C7 Cobb), graft subsidence (anterior/posterior, determined by the subsidence of anterior/posterior body height of fused segments; cranial/caudal, determined by the cranial/caudal plate-to-disc distances) and rate of fusion using lateral cervical X-rays of patients at 0, 6, 12 and 24months post-operatively. The Neck Disability Index (NDI) assessed clinical outcome pre-operatively and at 6, 12 and 24months post-operatively. Cervical lordosis (Cobb angle of fused segment) was 5.2° (± 4.2°) at 0months and 6.0° (± 5.7°) at 24months post-operatively. Graft subsidence was observed to occur at 6months post-operatively and continued throughout follow-up. Anterior, posterior and caudal subsidence occurred more in the first 12months post-operatively than in the following 12months (p<0.05). Average pre-operative NDI was 45%. Average NDIs were 18%, 13% and 10% at 6, 12 and 24months post-operatively, respectively. ACCF patients treated with TTMI demonstrated stable cervical lordosis over 2years of follow-up and 100% fusion rates after 2years. Measures of subsidence appeared to decrease with time. Patients experienced improved clinical outcomes over the 2-year period. PMID:27515543

  15. A Prospective Study of the Functional Outcome of Anterior Cervical Discectomy With Fusion in Single Level Degenerative Cervical Disc Prolapse

    Science.gov (United States)

    Kamani, Mayur M; Shetty, Vikram; Rai, H. Ravindranath; Hegde, Deepak

    2016-01-01

    Introduction Cervical spondylotic myelo-radiculopathy is a form of spinal cord dysfunction syndrome and usually accompanies age related degeneration of the spine. Aim To determine the functional outcome of anterior cervical discectomy with fusion and plating in single level degenerative cervical disc prolapse. Materials and Methods A total of 20 patients diagnosed with degenerative single level cervical disc prolapse who presented to the Department of Orthopaedic Surgery, Justice KS Hegde Charitable Hospital, Mangalore from the period of November 2012 to May 2014 were enrolled in the study. Complete clinical and radiological evaluation of the patients was done. A trial of conservative management was tried in all these patients for a period of two months. They were taken up for surgery only when conservative management had failed. Scoring of neck function before the surgery was done as per the Modified Japanese Orthopaedic Association (MJOA) score. All patients underwent anterior cervical discectomy and fusion (ACDF) with tricortical iliac crest bone grafting. Fixation was performed with titanium locking cervical plates. All patients were reviewed at 6 weeks and 6 months postoperatively. Assessment of neck function was done as per the MJOA scoring during all the reviews. Radiographic assessment was also done during all the reviews. The complications noted were documented. The statistical analysis was done using percentages; the arithmetic mean was calculated using SPSS software (version 16.0). Results Amongst the 20 patients included in the study, 1 patient died postoperatively due to oesophageal rupture. of the remaining 19 patients reviewed and followed up, all of them had improvement of symptoms and were reported to be in the ‘mild category’ as per the MJOA score. One patient developed dysphonia, in the immediate postoperative period due to recurrent laryngeal nerve palsy which recovered in a period of three months postoperative. Conclusion Single level

  16. Posterior compact Cotrel-Dubousset instrumentation for occipitocervical, cervical and cervicothoracic fusion

    OpenAIRE

    Korovessis, Panagiotis; Katonis, Pavlos; Aligizakis, Agisilaos; Christoforakis, Josef; Baikousis, Andreas; Papazisis, Zisis; Petsinis, Giorgos

    2001-01-01

    The authors report on 32 consecutive patients with instability at the craniocervical, cervical and cervicothoracic regions suffering from various pathologies, who were treated with posterior instrumentation and fusion using the posterior hooks-rods-plate cervical compact Cotrel-Dubousset (CCD) instrumentation alone or, in three patients, in combination with anterior operation. The patients were observed postoperatively for an average of 31 months (range 25–44 months) and evaluated both clinic...

  17. FGFR3–TACC3: A novel gene fusion in cervical cancer

    Directory of Open Access Journals (Sweden)

    Benedito A. Carneiro

    2015-08-01

    Full Text Available Cervical cancer epitomizes the success of cancer prevention through the human papillomavirus (HPV vaccine, but significant challenges remain in the treatment of advanced disease. We report the first three cases of cervical carcinoma harboring an FGFR3–TACC3 fusion, which serves as a novel therapeutic target. The fusion, identified by comprehensive genomic profiling, activates the FGFR pathway that has been implicated in HPV-driven carcinogenesis. One of the patients whose tumor contained the FGFR3–TACC3 fusion was treated with an investigational FGFR tyrosine kinase inhibitor. Concomitant molecular alterations involving the PI3K/AKT/mTOR and RAF/MEK pathways were also identified and suggest other treatment strategies that deserve investigation. This case series highlights the role of comprehensive genomic profiling in the identification of new therapeutic targets and in targeted therapy selection for patients with cervical cancer.

  18. Cervical total disc replacement is superior to anterior cervical decompression and fusion: a meta-analysis of prospective randomized controlled trials.

    Directory of Open Access Journals (Sweden)

    Yujie Zhang

    Full Text Available Despite being considered the standard surgical procedure for symptomatic cervical disc disease, anterior cervical decompression and fusion invariably accelerates adjacent segment degeneration. Cervical total disc replacement is a motion-preserving procedure developed as a substitute to fusion. Whether cervical total disc replacement is superior to fusion remains unclear.We comprehensively searched PubMed, EMBASE, Medline, and the Cochrane Library in accordance with the inclusion criteria to identify possible studies. The retrieved results were last updated on December 12, 2014. We classified the studies as short-term and midterm follow-up.Nineteen randomized controlled trials involving 4516 cases were identified. Compared with anterior cervical decompression and fusion, cervical total disc replacement had better functional outcomes (neck disability index [NDI], NDI success, neurological success, neck pain scores reported on a numerical rating scale [NRS], visual analog scales scores and overall success, greater segmental motion at the index level, fewer adverse events and fewer secondary surgical procedures at the index and adjacent levels in short-term follow-up (P 0.05.Cervical total disc replacement presented favorable functional outcomes, fewer adverse events, and fewer secondary surgical procedures. The efficacy and safety of cervical total disc replacement are superior to those of fusion. Longer-term, multicenter studies are required for a better evaluation of the long-term efficacy and safety of the two procedures.

  19. TRANSFORAMINAL L U MBAR INTERBODY FUSION IN LOW GRADE COMBINED LYTIC AND DEGENERATIVE SPONDYLOLIDTHESIS : FUNCTIONAL OUTCOME OF 21 CASES

    Directory of Open Access Journals (Sweden)

    Suresh

    2015-10-01

    Full Text Available BACKGROUND: Spondylolisthesis is a heterogenous disorder characterised by subluxation of a vertebral body in sagittal plane occuring frequently at l4 - 5 and l5 - S1commonest being isthmic and degenerative variety. While majority are asymptomatic, a subset do produce pain with neurology. Complete decompression of roots is essential, as is the need for solid stabi lization. Several fusion techniques were reported in literature like PLF, TLIF, PLF, ALIF On theoretical grounds, TLIF has been suggested to be safe and result in an improved outcome compared to other techniques. Data to support this view, are lacking. M ETHODS: A total of 21 patients (age range, 27 - 62 years with adult isthmic and degenerative spondylolisthesis were operated. There were 8 males and 13 females with mean age of 46.8 pre - op and 2 - year follow - up, pain (VAS and functional disability were quan tified by Oswestry Disability Index (ODI.Radiological union assessed with xrays by Brantigen and Steffee criteria. The global outcome was excellent in 90%.and 92% fusion. 2 patients presented motor deficit which did not recover. RESULTS: The follow - up was for 2 years. The mean VAS score for low back pain improved from 7.0 preoperatively to 2.1, as did the mean VAS score for leg pain from 6.7 to 1.4 and the mean ODI from 59.5% to 11.3%. CONCLUSION: TLIF does affect the 2 - year outcome of surgical treatment of spondylolisthesis with decreased back pain and ODI’s, with advantages of minimal thecal retraction, restored segmental lordosis and preserved posterior tension band.

  20. Acquired Pharyngeal Diverticulum after Anterior Cervical Fusion Operation Misdiagnosed as Typical Zenker Diverticulum.

    Science.gov (United States)

    Park, Jong Myung; Kim, Chang Wan; Kim, Do Hyung

    2016-08-01

    A pharyngeal diverticulum is a rare complication of an anterior cervical discectomy and fusion (ACDF). We present a case of a pharyngeal diverticulum after an ACDF, which was misdiagnosed as a typical Zenker diverticulum. A 54-year-old woman presented with dysphagia and a sense of irritation in the neck following C5 through C7 cervical fusion 3 years prior. The patient underwent open surgery to resect the diverticulum with concurrent cricopharyngeal myotomy. An ACDF-related diverticulum is difficult to distinguish from a typical Zenker diverticulum. PMID:27525244

  1. Posterior fixation and fusion with atlas pedicle screw system for upper cervical diseases

    Institute of Scientific and Technical Information of China (English)

    LI Lei; ZHOU Feng-hua; WANG Huan; CUI Shao-qian

    2008-01-01

    Objective: To evaluate the feasibility, safety and efficacy of atlas pedicle screws system fixation and fusion for the treatment of upper cervical diseases. Methods: Twenty-three consecutive patients with up-per cervical disorders requiring stabilization, including 19 cases of atlantoaxial dislocation (4 congenital odontoid disconnections, 6 old odontoid fractures, 4 fresh odontoid fractures of Aderson Ⅱ C, 3 ruptures of the C1 transverse ligament, and 2 fractures ofC1), 2 cases ofC2 tumor (instability after the resection of the tumors), and 2 giant neurilemomas of C2-C3(instability after resection of the tumors), were treated by posterior fixation and fusion with the atlas pedicle screw system, in which the screws were inserted through the posterior arch of Cr The operative time, bleeding volume and complications were reported. All patients were immobilized without external fixation or with rigid cervical collars for 1-3 months. All patients were followed up and evaluated with radiographs and CT. Results: In the 23 patients, 46 C1 pedicle screws, 42 C2 pedicle screws and 6 lower cervical lateral mass screws and 2 lower cervical pedicle screws were placed. The mean operative time and bleeding volume was 2.7 hours and 490 ml respectively. No intraoperative complications were directly related to surgical technique. No neurological, vascular or infective complications were encountered. All patients were followed up for 3-36 months (average 15 months). Firm bony fusion was documented in all patients after 3-6 months. One patient with atlas fracture showed anterior occipitocervical fusion. There was no implant failure. Conclusions: Posterior fixation and fusion of the atlas pedicle screw system is feasible and safe for the treatment of upper cervical diseases, and may be applicable to a larger number of patients.

  2. Applied anatomy of presacral approach for axial lumbar interbody fusion%轴向腰椎椎间融合术入路的应用解剖

    Institute of Scientific and Technical Information of China (English)

    李向明; 张玉松; 侯致典; 吴涛; 丁自海

    2011-01-01

    Objective The aim of this study was to evaluate the safety of the presacral approach for axial lumbar interbody fusion.Methods (1) The pelvic region of 12 adult cadavers was dissected and analyzed.All specimens were divided in the median sagittal plane.The main goal of these dissection was to understand the fascial structures of the presacral space and measure some data correlated with the rectosacral fascia and pelvic splanchnic nerves.(2) The blunt guide pin was inserted using the technique described by Marotta into 24 pelvic-halves, the distance from the trocar to important structures in the presacral space was measured.Results (1) The fascial structures of the presacral space was multilaminar, it could be divided into five levels.(2) The rectosacral fascia was found in 11 out of 12 specimens (91.7%),it originated from the parietal presacral fascia at the level of S2 in 16.7% ,S3 in 41.7% and S4 in 33.3%.The presacral space was divided into superior and inferior portions by the rectosacral fascia.(3) Pelvic splanchnic nerves confined the dissection of the lower rectum, its length which could be used as a measure of the'sagittal safe zone' for presacral space was (22.9±3.2)mm.(4) In this study, the shortest distance from the guide pin to pelvic splanchnic nerves was (7.8 ±l.9)mm, the vertical distance to the S3/4 junction was (15.0 ±3.6)mm.Conclusion It is risky to perform the presacral approach for axial lumbar interbody fusion because of the presence of the rectosacral fascia, presacral venous plexus and the vascular variations.%目的 探讨经骶前间隙轴向腰椎椎间融合术入路的安全性.方法 (1) 12具(24侧)防腐固定成人骨盆段标本,解剖骶前间隙,观察骶前的筋膜层次,骶直肠筋膜,盆内脏神经等,测量骶直肠筋膜和盆内脏神经的相关解剖数据.(2)参照Marotta方法,模拟手术置入导针,测量导针在骶前间隙中的相关解剖学数据.结果 (1)骶前的筋膜可分为5层;(2)

  3. The Use of Bone Morphogenetic Protein in Pediatric Cervical Spine Fusion Surgery: Case Reports and Review of the Literature

    OpenAIRE

    Molinari, Robert W.; Molinari, Christine

    2015-01-01

    Study Design Case report. Objective There is a paucity of literature describing the use of bone graft substitutes to achieve fusion in the pediatric cervical spine. The outcomes and complications involving the off-label use of bone morphogenetic protein (BMP)-2 in the pediatric cervical spine are not clearly defined. The purpose of this article is to report successful fusion without complications in two pediatric patients who had instrumented occipitocervical fusion using low-dose BMP-2. Meth...

  4. Comparison of the effect of posterior lumbar interbody fusion with pedicle screw fixation and interspinous fixation on the stiffness of adjacent segments

    Institute of Scientific and Technical Information of China (English)

    LI Chun-de; SUN Hao-lin; LU Hong-zhang

    2013-01-01

    Background Adjacent segment degeneration could seriously affect the long-term prognosis of lumbar fusion.Dynamicfixation such as the interspinous fixation,which is characterized by retaining the motion function of the spinal segment,has obtained satisfactory short-term effects in the clinical setting.But there are few reports about the biomechanicalexperiments on whether dynamic fixation could prevent adjacent segment degeneration.Methods The surgical segments of all 23 patients were L4/5.Thirteen patients with disc herniation of L4/5 underwentWallis implantation surgery,and 10 patients with spinal stenosis of L4/5 underwent posterior lumbar interbody fusion(PLIF).L3-S1 segmental stiffness and displacement were measured by a spine stiffness gauge (SSG) device duringsurgery when the vertebral plate was exposed or during spinal decompression or internal fixation.Five fresh,frozencadavers were used in the self control experiment,which was carried out in four steps:exposure of the vertebral plate,decompression of the spinal canal,implantation of a Wallis fixing device,and PLIF of L4/5 after removing the Wallis fixingdevice.Then,L3-S1 segment stiffness was measured by an SSG device.Results The experiments showed that the average stiffness of the L4/5 segment was (37.1±8.9) N/mm after exposure of the vertebral plate,while after spinal decompression,the average stiffness fell to (26.2±7.1) N/mm,decreasing by 25.8% (P <0.05).For the adjacent segments L3/4 and L5/S1,their stiffness showed no significant difference between the L4/5 segment decompression and the exposure of the vertebral plate (P >0.05).After Wallis implantation of L4/5,the stiffness of the cephalic adjacent segment L3/4 was (45.8±10.7) N/mm,which was 20.5% more than that after the exposure of the vertebral plate (P <0.05); after L4/5 PLIF surgery,the stiffness of L3/4 was (35.3±10.7) N/mm and was decreased by 12.4% more than that after the exposure of the vertebral plate (P <0.05).The

  5. Combined transforaminal lumbar interbody fusion with posterolateral instrumented fusion for degenerative disc disease can be a safe and effective treatment for lower back pain

    Directory of Open Access Journals (Sweden)

    Ara J Deukmedjian

    2015-01-01

    Full Text Available Background: Lumbar fusion is a proven treatment for chronic lower back pain (LBP in the setting of symptomatic spondylolisthesis and degenerative scoliosis; however, fusion is controversial when the primary diagnosis is degenerative disc disease (DDD. Our objective was to evaluate the safety and effectiveness of lumbar fusion in the treatment of LBP due to DDD. Materials and Methods: Two-hundred and five consecutive patients with single or multi-level DDD underwent lumbar decompression and instrumented fusion for the treatment of chronic LBP between the years of 2008 and 2011. The primary outcome measures in this study were back and leg pain visual analogue scale (VAS, patient reported % resolution of preoperative back pain and leg pain, reoperation rate, perioperative complications, blood loss and hospital length of stay (LOS. Results: The average resolution of preoperative back pain per patient was 84% (n = 205 while the average resolution of preoperative leg pain was 90% (n = 190 while a mean follow-up period of 528 days (1.5 years. Average VAS for combined back and leg pain significantly improved from a preoperative value of 9.0 to a postoperative value of 1.1 (P ≤ 0.0001, a change of 7.9 points for the cohort. The average number of lumbar disc levels fused per patient was 2.3 (range 1-4. Median postoperative LOS in the hospital was 1.2 days. Average blood loss was 108 ml perfused level. Complications occurred in 5% of patients (n = 11 and the rate of reoperation for symptomatic adjacent segment disease was 2% (n = 4. Complications included reoperation at index level for symptomatic pseudoarthrosis with hardware failure (n = 3; surgical site infection (n = 7; repair of cerebrospinal fluid leak (n = 1, and one patient death at home 3 days after discharge. Conclusion: Lumbar fusion for symptomatic DDD can be a safe and effective treatment for medically refractory LBP with or without leg pain.

  6. Clinical efficacy of three different techniques of fusion in the treatment of cervical spondylotic myelopathy%三种前路手术治疗脊髓型颈椎病临床疗效观察

    Institute of Scientific and Technical Information of China (English)

    陈占磊; 官众

    2013-01-01

    Objective To observe the clinical effects of cervical spondylotic myelopathy and bone graft fusion by different methods for cervical spondylotic myelopathy.Methods Seventy-one cases of cervical spondylotic myelopathy were treated by cervical anterior decompression and bone graft fusion with three surgical procedures from January 2009 to November 2011.Twenty-four cases were treated by anterior cervical discectomy and bone grafting and fusion (group A),27 cases were treated by cervical anterior decompression bone grafting and internal fixation with steel plate (group B),20 cases were treated by anterior cervical decompression,titanium plate internal fixation(group C),cervical disc prosthesis implantation.X-ray films and regular follow-up were taken after operation to observe the curative effects,the interbody height,the cervical vertebra antecttrvature and the fusion of operative segments.Results According to the results of the follow-up,the fusion rates of A,B,C group were 95.3%,95.4%,97.8%.When the follow-up was over,while there was no such difference in A,B or C group (F =2.32,P > 0.05),while there was no statistical significance in the differences among A,B or C group (F =2.23,P > 0.05).Condusions The key point of the treatment of cervical spondylotic myclopathy lies in thorough decompression and effective bone graft fusion,furthermore,different techniques of fusion affect the curative effects significantly.%目的 观察分析三种颈椎前路手术治疗脊髓型颈椎病(CSM)的临床疗效.方法 将2009年1月至2011年11月青海大学附属医院手术治疗的71例CSM患者分为A、B、C三组.A组24例采用颈椎前路减压植骨钢板内固定术;B组27例采用颈前路减压cage植入植骨术;C组20例采用颈椎间盘切除减压、人工颈椎间盘植入术.术后定期随访及拍摄X线片,观察疗效、椎间高度、颈椎前弯曲度和植骨融合情况.结果 经过随访,A组融合率为95.3%,B组为95.4%,C组为97.8

  7. 后路腰椎椎体间融合术治疗腰椎滑脱的临床疗效%Posterior lumbar interbody fusion for treament of lumbar spondylolisthesis

    Institute of Scientific and Technical Information of China (English)

    陈德龙; 陈小强; 叶永松

    2014-01-01

    Objective To evaluate the effectiveness of posterior lumbar interbody fusion for the treatment of lumbar spondylolis-thesis and provide reference for clinical therapeutics .Methods A tatal of 40 cases of adult lumbar spondylolisthesis patients trea-ted by posterior lumbar interbody fusion were reviewed .All cases were followed up at least 3 years.Comparative analysis about Oswestry disability index (ODI), visual analogue scale (VAS) score and the Japanese Orthopaedic Association (JOA) score chan-ges before and after treatment of 1 and 3 years were performed.Results The height of intervertebral disc height and foraminal gap had a significant differences (P0.05) between after treatment 1 years and after 3 years.ODI, low back pain VAS score, leg pain VAS score and JOA score had a significant differences (P0.05) between after treatment 1 years and after 3 years.Conclusion Posterior lumbar interbody fusion can recon-struct the stability of the lumbar spine.Clinical symptoms improvement can be achieved after surgry.This surgry is ideal for the treatment of spondylolisthesis.The mid-and long-term follow-up results are satisfactory.%目的:探讨后路腰椎椎体间融合术( posterior lumbar interbody fusion , PLIF)治疗腰椎滑脱的中期疗效,对腰椎滑脱症的临床治疗提供指导意见。方法回顾性分析采用PLIF治疗的腰椎滑脱40例,所有病例随访观察>3年,对手术前后影像学资料、Oswestry功能障碍指数( Oswestry disability index , ODI )、视觉模拟量表( visual analog scale , VAS)评分及日本骨科学会( Japanese Orthopaedic Association ,JOA)腰背痛手术治疗评分标准的评分变化情况进行比较分析。结果椎间隙高度、椎间孔高度术后1年、3年与术前比较差异均有统计学意义( P<0.05);术后1年与术后3年测量值比较差异不具有统计学意义(P>0.05)。 ODI、腰痛VAS评分、腿痛VAS评分及JOA评分术前和术后1

  8. 可吸收聚合物材料制作椎间融合器的临床应用%Clinical application of bioabsorbable polymer interbody fusion cage

    Institute of Scientific and Technical Information of China (English)

    王乐; 刘少喻

    2013-01-01

    背景:可吸收聚合物材料用于制作椎体间融合器目前是研究的热点,且存在争议。目的:综述可吸收聚合物材料椎间融合器的基础研究及临床应用进展。  方法:以“椎间融合器,可吸收性,动物实验,临床研究; spine,bioabsorbable,intervertebral fusion”为关键词,应用计算机检索维普数据库、万方数据库和PubMed 数据库1989年1月至2012年6月与可吸收聚合物材料椎间融合器相关的文献,总结可吸收聚合物材料椎间融合器基础研究和应用方面的最新进展。  结果与结论:基础研究显示,可吸收聚合物材料椎间融合器可有效促进椎间融合,最主要的缺陷是植入体内产生的迟发型炎症反应和大块侵蚀作用,以及降解与融合速度,机械强度与孔隙率等方面尚待进一步研究。目前,聚乳酸及其衍生的混合共聚物正应用于临床且相关研究正逐步开展。该材料最主要的优势在于其应用于融合器时可针对不同需要灵活改变参数,但融合器周围组织良好的血运和成血管作用十分重要,而且支架孔隙率和其他关键参数可影响融合器的机械强度,要求其在能承受必要压力载荷的同时也可提供足够的空间,满足细胞迁移、血管生成,从而促进骨融合,因此寻找最优化的参数组合在骨组织工程研究领域仍是一项挑战。%BACKGROUND:Bioabsorbable polymer materials used in interbody fusion are currently a hot research, and there is stil no consensus. OBJECTIVE:To summarize the basic research and clinical application of bioabsorbable polymer interbody fusion cages. METHODS:A search of literatures in the database of Wanfang, VIP and PubMed databases from January 1989 to June 2012 was performed with the key words of“intervertebral fusion;bioabsorbable;spine;animal experiment;clinical research”in Chinese and English, respectively. Al the literatures

  9. Bioresorbable cage for interbody fusion Progress in research and clinical application%可吸收椎间融合器的理论研究及临床应用

    Institute of Scientific and Technical Information of China (English)

    孙浩林; 李淳德

    2008-01-01

    险带来了相应技术的发展.结论:可吸收椎间融合器的研究和应用仍处于起步阶段,但现有的研究结果已经预示了其进一步研究和临床应用发展前景.%BACKGROUND: The use of interbody cages is rapidly increasing in filed of spinal fusion surgery. The inherent limitations of conventional cages such as cage migration or failure, radiopacity, fusion stress shielding, late-onset inflammation and osteolysis give some impetus for the development of bioresorbable cages. Compared with conventional cages, they show better rigidity and elasticity coefficient, with less interference on the imaging evaluation. OBJECTIVE: To introduce the materials classification and property, animal studies, clinical application, current drawbacks and future directions of bioresorbable fusion cages, and provide objective evidences for the research and clinical application of the cages.RETRIEVAL STRATEGY: The relevant articles published between December 1990 and December 2006 were searched for in Pubmed database by the researchers of this article, with the key words "bioresorbable cages, spine, SCI" in English. A total of 550 articles were selected and reviewed preliminarily by the inclusive standards of: research about materials, animal studies and clinical application of bioresorbable cages. Exclusion criteria: repetitive studies.LITERATURE EVALUATION: The main sources of literatures are researches about materials, animal studies and clinical application of bioresorbable cages. Among the 27 selected articles, 1 is review, while others are clinical or elementary experimental studies. DATA SYNTHESIS: ①Materials: Polylactides becomes the most useful and applied base material for bioresorbable spinal interbody cages; characteristics of bioresorbable materials include crystallinity, average molecular weight, molecular weight distribution (polydispersity), and glass transition temperature. There are also several points to consider in the design of

  10. [Langerhans cell histiocytosis causing cervical myelopathy].

    Science.gov (United States)

    Doléagbénou, A K; Mukengeshay Ntalaja, J; Derraz, S; El Ouahabi, A; El Khamlichi, A

    2012-08-01

    Langerhans cell histiocytosis (LCH), a disorder of the phagocytic system, is a rare condition. Moreover, spinal involvement causing myelopathy is even rare and unusual. Here, we report a case of atypical LCH causing myelopathy, which was subsequently treated by corporectomy and fusion. An 8-year-old boy presented with 3 weeks of severe neck pain and limited neck movement accompanying upper and lower limbs motor weakness. CT scans revealed destruction of C5 body and magnetic resonance imaging showed a tumoral process at C5 with cord compression. Interbody fusion using anterior cervical plate packed by autologus iliac bone was performed. Pathological examination confirmed the diagnosis of LCH. After the surgery, the boy recovered from radiating pain and motor weakness of limbs. Despite the rarity of the LCH in the cervical spine, it is necessary to maintain our awareness of this condition. When neurologic deficits are present, operative treatment should be considered. PMID:22552159

  11. Epidemiologic trends in the utilization, demographics, and cost of bone morphogenetic protein in spinal fusions

    OpenAIRE

    Louie, Philip K.; Hassanzadeh, Hamid; Singh, Kern

    2014-01-01

    Bone morphogenetic protein (BMP) utilization as an adjunct for spinal arthrodesis has gained considerable momentum among spine surgeons. Despite carrying Food and Drug Administration approval for only single level anterior lumbar interbody fusion from L4-S1, the majority of BMP administration is in “off label” settings. Over the last decade, BMP utilization has increased in all facets of spine surgery with the only exception being the anterior cervical spine, in which a downward trend resulte...

  12. Artificial cervical disc replacement and anterior cervical decompression and fusion for the treatment of single segmental cervical disc herniation:a 3-year follow-up%颈椎人工间盘置换与前路减压融合修复单节段颈椎间盘突出症:3年随访

    Institute of Scientific and Technical Information of China (English)

    程俊杰; 眭江涛; 马原; 田慧中

    2015-01-01

    stages. Artificial disc replacement can not only play a role in mitigation of cervical disease neurological symptoms and signs, but also maintain stability and semental activity of cervical spine, and reduce secondary adjacent segmental degeneration. These two methods which applied in cervical degenerative intervertebral disc herniation stil remain controversial. OBJECTIVE:To investigate the short-term effect of artificial cervical disc replacement and anterior cervical decompression and fusion for the treatment of single segmental cervical disc herniation. METHODS:Total y 48 patients with single segment radiculopathy or myelopathy cervical diseases induced by cervical disc herniation that required surgery and received a three-month fol ow-up were included and retrospectively analyzed. These patients were divided into replacement group (n=21) and fusion group (n=27) according to the different repair programs. Patients in the replacement group were subjected to Prestige LP cervical artificial disc replacement, and patients in the fusion group were subjected to disc fusion using interbody fusion cage of Johnson or al ogeneic fibularing. They were fol owed up at 1 week, 3, 6, 12, 24, 36 months after treatment. Complications were recorded during the fol ow-up. The pain of patients was evaluated using neck and upper limb pain visual analogue scale scores. The therapeutic effect was evaluated using Japanese Orthopaedic Association (JOA) score. The clinical symptoms improvement and daily functional status of patients after treatment were evaluated using cervical disability index. RESULTS AND CONCLUSION:During the final fol ow-up, the fusion rate in fusion group was 93%(25/27). Comparisons between groups:at the 1 week and final fol ow-up after treatment, the visual analog scale scores of neck and upper limbs and cervical dysfunction indexes were al lower than those before treatment;the Japanese Orthopaedic Association scores were higher than those before treatment (P0.05). The

  13. 经椎间孔行椎体间融合术治疗腰椎退行性疾病的临床分析%Clinical Analysis of Transforaminal Lumbar Interbody Fusion for the Treatment of Lumbar Degenerative Disease

    Institute of Scientific and Technical Information of China (English)

    吴永忠

    2015-01-01

    Objective:To explore the clinical curative effect of transforaminal lumbar interbody fusion for the treatment of lumbar degenerative disease.Method:The clinical data of 60 patients with lumbar degenerative disease who were treated by transforaminal lumbar interbody fusion in our hospital from January 2011 to May 2013 were retrospectively analyzed. And 65 patients with posterolateral lumbar fusion at the same time were compared and analyzed.Result:(1)The ODI dysfunction index and the VAS scores of waist and leg pain of patients in the two groups postoperative were significantly lower than those of preoperative(P<0.01),and the VAS scores of waist and leg pain of patients in the TLIF group postoperative were significantly lower than those of patients in the PLF group(P<0.05).(2)The postoperative osseous fusion rate of patients in the TLIF group was 100%,which was obviously higher than 86.15% of patients in the PLF group,the difference was statistically significant(P<0.05).(3)The lumbar lordosis angle and relative height of intervertebral disc in the two groups postoperative were significantly improved compared with preoperative,and the lumbar lordosis angle and relative intervertebral disc height in the TLIF group were increased obviously compared with the PLF group,the differences were statistically significant(P<0.05).Conclusion:The transforaminal lumbar interbody fusion and posterolateral lumbar fusion have preferable clinical curative effects for patients with lumbar degenerative diseases, but the extent of the waist and leg pain relief,convergence rate and intervertebral height adjustment of patients by the transforaminal lumbar interbody fusion are superior than those of patients by posterolateral lumbar fusion,so will the transforaminal lumbar interbody fusion can be regarded as a optimizing operation scheme for lumbar degenerative disease.%目的:探讨经椎间孔行椎体间融合术对腰椎退行性疾病的临床疗效。方法:对本院2011年1

  14. Influence of posterior lumbar interbody fusion to adjacent segment degeneration%后路腰椎椎间融合术对邻近节段退变的影响

    Institute of Scientific and Technical Information of China (English)

    管俊杰; 石志才

    2011-01-01

    Objective Lumbar interbody fusion induces the change of lumbar normal biomechanical environment. The adjacent segments have the character of stress concentration. This study aimed to observe the lurnhar adjacent segment degeneration(ASD) after posterior lumbar interbody fusion(PLIF). Methods From 2002 to 2006, 60 patients (38 males and 22 females, aged 25-77 years old, with a mean value of 46 years old) with symptomatic degenerative diseases underwent PLIF The incidence of ASD, position and radiographic characteristics were studied. The relation between “floating fusion” and ASD were compared, and the relation of fusion range and ASD was also studied. Results All patients were followed up for 2.0-6.5 years ( mean 4.5 years). Eleven patients ( 18.3% ) were found to have radiographic characteristics of ASD. Nine of them had ASD at cranial segments, the other 2 at caudal segnents. The difference between using “floating fusion” or not in the risk of ASD was not statistically significant. The dffference between single-level fusion and double-level fusion was not statisticaly significant, either. Conclusion After PLIF, stress concentration of adjacent segments was abnormal ,which increases the incidence of ASD. The cranial segment has a higher degeneration risk than the caudal segment.%目的 腰椎融合术改变了腰椎的生物力学环境,使邻近节段应力集中,本研究就后路腰椎椎间融合术(posterior lumbar interbody fusion,PLIF)对邻近节段退变(adjacent segment degeneration,ASD)的影响进行探讨.方法 2002~2006年,采用PLIF治疗腰椎退行性疾病患者60例,其中男38例,女22例;年龄为25~77岁,平均46岁.观察其术后ASD的发生率、发生部位及影像学特点,对是否"悬浮固定"及内固定融合范围引发ASD的风险进行对比.结果 所有患者随访2.0~6.5年,平均4.5年.影像学有退变表现者11例(18.3%),其中9例发生在内固定头侧邻近节段,2例发生在尾侧邻近节段.是

  15. Extreme Lateral Interbody Fusion Procedure

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    Full Text Available ... with the questions, these other questions on the web for him. 00:49:58 FERNANDO VALE, MD: ... you can go to the Tampa General Hospital web page, we can get access through physician finder. ...

  16. Extreme Lateral Interbody Fusion Procedure

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    Full Text Available ... could potentially go home within one or two days after surgery. As a matter of fact, we ... or typical open procedure. Now, pedicle screws these days still can be placed through a minimal access ...

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    Full Text Available ... any questions, to please get it on the internet right now, because we are almost done to ... Tampa General Hospital web page, we can get access through physician finder. Dr. Juan Uribe, the surgeon, ...

  18. Extreme Lateral Interbody Fusion Procedure

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    Full Text Available ... much of muscle, minimizing the trauma to the soft tissue. And these are different shots, again, of the ... fusing the spine with minimal trauma to the soft tissue, and that way the patient can recover faster, ...

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    Full Text Available ... perform this operation. Of course, everything requires a learning curve. This is something that is done many ... cameras don't have -- we cannot get them deep enough to look at the disc space, but ...

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    Full Text Available ... perform this operation. Of course, everything requires a learning curve. This is something that is done many ... us to hammer to get access to the problem. What he's doing at this stage is basically ...

  1. Extreme Lateral Interbody Fusion Procedure

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    Full Text Available ... tube has numbers that is telling me how deep is the spine from here. So we set ... dilators are placed and a retractor is placed deep inside in the wound to allow visualization of ...

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    Full Text Available ... see, it's made of PEEK, that is a plastic material and has openings that allow for placement ... seen before is made of PEEK, that is plastic, but is real strong plastic, has been tested ...

  3. Extreme Lateral Interbody Fusion Procedure

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    Full Text Available ... procedure. Dr. Uribe is the assistant professor of neurosurgery at the University of South Florida College of ... at the University of South Florida, Department of Neurosurgery, acting chief of the spine section. Dr. Juan ...

  4. Extreme Lateral Interbody Fusion Procedure

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    ... procedure. Dr. Uribe is the assistant professor of neurosurgery at the University of South Florida College of ... at the University of South Florida, Department of Neurosurgery, acting chief of the spine section. Dr. Juan ...

  5. Extreme Lateral Interbody Fusion Procedure

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    Full Text Available ... of Medicine. He will be joined by Dr. Fernando Vale, vice chief of the Neurosciences Department at ... Now let's join the doctors. 00:01:17 FERNANDO VALE, MD: Welcome, everybody. We are live in ...

  6. Extreme Lateral Interbody Fusion Procedure

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    Full Text Available ... you have this many assistants, to make our life a lot easier in surgery. And again, he's ... spine is. It's hard bone, we have to work through this bony surface. As you can see, ...

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    Full Text Available ... webcast screen and open the door to informed medical care. Now let's join the doctors. 00:01: ... webcast screen and open the door to informed medical care. 00:59:48 [ end of webcast

  8. Extreme Lateral Interbody Fusion Procedure

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    Full Text Available ... General Hospital in Tampa, Florida, Room 18. Today I'd like to present one of my colleagues, ... in Tampa, Florida. My name is Fernando Vale, I will be the narrator of this procedure. I ...

  9. Extreme Lateral Interbody Fusion Procedure

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    Full Text Available ... 32 FERNANDO VALE, MD: Okay, well the few things that I would like to readdress, number one, it's extremely important that we have good fluoroscopy. I mean, good x-rays. We need ...

  10. Extreme Lateral Interbody Fusion Procedure

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    Full Text Available ... down to the psoas muscle that is a large muscle that helps stabilize the spine. From there, ... the lumbar spine with the nerve. That's the large muscle that we call the psoas. This muscle ...

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    Full Text Available ... This muscle is really important for us to work around, and we have to go through that ... levels to approach from the lateral approach. It works really well at L4/5, L3/4, L2/ ...

  12. Extreme Lateral Interbody Fusion Procedure

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    Full Text Available ... injure them. So now I can have a mapping where the nerves are. Now back to you, ... spondylosis, they can potentially benefit from this surgical intervention. The idea is to remove the disc and ...

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    Full Text Available ... that normal height, try to restore that normal anatomy, and that way open up the nerve, open ... on the cage in between to allow that anatomy to be restored again. And these are all ...

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    Full Text Available ... severe facet disease. These are all stages of arthritis. And it will happen to anybody. It will ... suffering from severe lumbar spondylosis. Again, spondylosis means arthritis, which results in pain, nerve damage, and all ...

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    Full Text Available ... minimize muscle destruction. We go from the side, split the muscle apart, and get access to the ... we have the flank on the side, we split the skin and the fascia and get down ...

  18. Extreme Lateral Interbody Fusion Procedure

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    Full Text Available ... to be stable. Another question is: can it be rejected? Well, we've never seen it. This cage that ... about rejection from a device like this. It's well-incorporated in the body, especially in the spine. More questions: can it be done at age 70 and older? Absolutely. It's ...

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  20. A radiological evaluation of allografts (ethylene oxide sterilized cadaver bone and autografts in anterior cervical fusion.

    Directory of Open Access Journals (Sweden)

    Parthiban J

    2002-01-01

    Full Text Available Serial roentgenograms of 40 patients who had 70 cervical intervertebral spaces grafted with ethylene oxide sterilized cadaver bone and 28 patients who received 44 iliac crest auto grafts for anterior cervical spine fusion, were studied. The radiological evaluation was made on the basis of settlement of intervertebral spaces, fusion rate, delayed union, non-union, graft collapse and extrusion of the graft. Indigenous methodologies were designed for the assessment of settlement of grafted intervertebral spaces in percentage. Disc space settlement was more common in autografts (93% cases than in allografts (80% cases. The average percentage of settlement of intervertebral disc space (S% was 22 in autografts and 28 in allografts during the first four months. By the end of eight months, allograft disc spaces settle more. No significant difference was noted in fusion rate at the end of one year viz. allografts (90% cases and autografts (93% cases. Autograft and allograft (ethylene oxide sterilized cadaver bone are equally useful in anterior cervical spine fusions.

  1. Design and clinical application of cervical hollow threaded fixator

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Objective Cervical hollow threaded fixator (CHTY) was designed and applied to stabilize tha cervical spine following anterior decompression due to cervical spondylosis or acute cervical disc herniation. Methods Medical use titanium alloy with no magnetism was made into a hollow threaded structure with holes on the wall of the fixator. Forly-two patients with cervical spondylosis and acute cervical disc herniation were stabilized using the CHTF technique after anterior decompression. X-ray films and CT scans were taken after the oberation to observe the stability ann fusion rate of the segments. Results Patients were allowed to walk one day after the operation and were followed up for 6 to 36 months. The operated segments were stable and solid fusion was observed 3-6 months after surgery. Conclusions Immediate stability of the operated segments can be obtained using the CHTF technique. Patients ware easy to manage after5 the operation and returned to their jobs in a short time.The CHTF technique is safe and simpa to perfoirme and eliminates the complications of an autograft.It may be an alternative to traditional cervical interbody fusion with bone graft.

  2. 改良的腰椎后路植骨融合术治疗腰椎退行性疾病的疗效%Modified Posterior Lumbar Interbody Fusion for Lumbar Degenerative Diseases

    Institute of Scientific and Technical Information of China (English)

    高松; 马勇; 张斌; 刘远

    2014-01-01

    目的:探讨改良的腰椎后路椎间植骨融合术治疗腰椎退行性疾病的临床疗效。方法对76例腰椎退行性疾病患者均采用改良的腰椎后路椎间植骨融合术治疗,并采用视觉模拟评分(VAS)法、日本骨科协会评估治疗分数(JOA)评分法对76例患者术前、术后随访3个月时进行VAS、JOA评分。术后随访1年,行X线检查,同时观察植骨融合率的情况。结果76例患者术后随访3个月VAS得分明显低于术前、JOA得分明显高于术前(P<0.05)。术后随访1年,X线检查示76例患者植骨块无明显移位,无断钉、断棒和松动;植骨融合率为97.4%(74/76)。结论改良的腰椎后路椎间植骨融合术是治疗腰椎退行性疾病的一种有效方法。%Objective To explore the clinical efficacy of modified posterior lumbar interbody fusion (PLIF) in the treatment of lumbar degenerative diseases. Methods Seventy-six patients with lumbar degenerative diseases were treated with the modified PLIF. The clinical outcomes were evaluated by visual analog scale (VAS) and Japanese Orthopedic Association (JOA) scores before and 3 months after operation. The rate of fusion was measured by X-ray 1 year after operation. Results VAS scores decreased and JOA scores increased after operation (P<0.05). No obvious bone graft displacement, screw breakage, rod breakage and screw loosening were found in all patients after 1 year of follow-up. The bone graft fusion rate was 97.4%(74/76).Conclusion The modified posterior lumbar interbody fusion is effective for lumbar degenerative diseases.

  3. A computed tomography morphometric study of occipital bone and C2 pedicle anatomy for occipital-cervical fusion

    OpenAIRE

    Nicolas K.K. King; Tiruchelvarayan Rajendra; Ivan Ng; Wai Hoe Ng

    2014-01-01

    Background: Occipital-cervical fusion (OCF) has been used to treat instability of the occipito-cervical junction and to provide biomechanical stability after decompressive surgery. The specific areas that require detailed morphologic knowledge to prevent technical failures are the thickness of the occipital bone and diameter of the C2 pedicle, as the occipital midline bone and the C2 pedicle have structurally the strongest bone to provide the biomechanical purchase for cranio-cervical instrum...

  4. Introduction and evaluation of an anterior interbody fusion model on rabbits%一种兔腰椎间融合模型的建立及效果评价

    Institute of Scientific and Technical Information of China (English)

    汤嘉军; 杨宇超; 陈国荣; 张忠民

    2015-01-01

    目的:利用兔腰椎骨性结构测量数据建立一种稳定的腰椎椎体间植骨融合模型,为组织工程学研究提供标准化的模型参考。方法选用健康新西兰大白兔(2~2.5 kg)44只,随机分为A、B、C、D四组,A组(n=10)用于解剖进行腰椎椎体测量,B组(n=12)行L4/5椎体间椎骨融合术加内固定;C组(n=12只)行L4/5椎体间植骨融合术未进行内固定,D组(n=10)行单纯显露加横突破坏。B、C、D 3组造模后4周行X线检查,术后12周取标本进行大体观察、Micro-CT、生物力学及组织学切片检查。结果 B组仅出现1例因固定螺钉进入椎管导致脊髓损伤造成双下肢瘫痪。手触法检测B组融合率为100%(12/12),C组融合率为75%(9/12),D组标本未见椎间盘损伤及间隙破坏。影像学B组植入骨块位置明显优于C组,融合评分明显高于C组(P<0.05)。组织学提示B、C两组椎体间融合部位均可见新生软骨,C组中可见植骨块脱出后形成软组织空腔。生物力学显示B组最大载荷显著高于C组(P<0.05)。结论在兔腰椎解剖基础上进行兔腰椎间植骨融合模型制作是安全、可靠的。内固定装置可以为椎间植骨块提供稳定的融合空间,防止植骨块脱离融合位置,有助于提高该模型的融合效率。%Objective In order to provide a standardized model for tissue engineering research,we took measurement of lumbar bodies on rabbits to establish a stable interbody fusion model. Methods Forty-four healthy adult New Zealand white rabbits (2~2.5 kg) were randomly divided into an anatomical analysis group (group A, n=10), an interbody fusion with fixation group (group B, n=12), an interbody fusion with no fixation group(group C, n=12) and a blank control group (group D, n=10). Animals in group B、C、D underwent x-ray examination at 4 weeks after operation. At 12 weeks all rabbits were euthanasized, the fusion segments were

  5. Design of Lamifuse : a randomised, multi-centre controlled trial comparing laminectomy without or with dorsal fusion for cervical myeloradiculopathy

    NARCIS (Netherlands)

    Bartels, R.H.M.A.; Verbeek, A.L.M.; Grotenhuis, J.A.

    2007-01-01

    BACKGROUND: laminectomy is a valuable surgical treatment for some patients with a cervical radiculomyelopathy due to cervical spinal stenosis. More recently attention has been given to motion of the spinal cord over spondylotic spurs as a cause of myelopathic changes. Immobilisation by fusion could

  6. Laminoplasty instead of laminectomy as a decompression method in posterior instrumented fusion for degenerative cervical kyphosis with stenosis

    OpenAIRE

    Yeh, Kuang-Ting; Lee, Ru-Ping; Chen, Ing-Ho; Yu, Tzai-Chiu; Liu, Kuan-Lin; Peng, Cheng-Huan; Wang, Jen-Hung; Wu, Wen-Tien

    2015-01-01

    Background Posterior laminectomy with instrumented fusion is a standard procedure for treating degenerative cervical kyphosis with stenosis (DCKS). Two major disadvantages of the surgery are adhesion of the dural membrane with significant disfiguring of cervical spine and a small fusion bed around the lateral mass. One of the advantages of laminoplasty over laminectomy is the protection of the dural membrane from adhesion through preservation of posterior bony elements. This study presents th...

  7. 改良TLIF治疗腰椎退变性疾病%Modified transforaminal lumbar interbody fusion for the treatment of lumbar degenerative disease

    Institute of Scientific and Technical Information of China (English)

    荣树; 马兆钦

    2011-01-01

    目的 探讨改良TLIF治疗腰椎退变性疾病的疗效.方法 用改良TLIF手术治疗L~S退变性疾病患者24例,共融合40个节段,其中单节段8例,双节段16例.男14例,女lO例;年龄56~78岁,平均64.6岁.退变性滑脱伴椎管狭窄6例,峡不连性滑脱4例,退变性腰椎管狭窄症10例,巨大椎间盘脱出合并椎间失稳4例.术中根据病情需要,采用椎管扩大减压后切除整个下关节突,切除上关节突上部的内侧半,部分开放椎间孔后壁,椎间隙自体微粒骨打压植骨,Cage斜向中线40.方向植入椎间隙,辅以椎弓根螺钉固定完成改良TLIF.结果 术中无并发症发生,24例均获得随访,时间12~20个月,平均17.4个月.所有患者于术后1年随访时均达椎体间融合,无螺钉断裂和Cage移位、沉陷.10例腰椎滑脱者滑脱完全复位并维持良好.根据JOA评分法,本组术前(13.8±4.1)分,末次随访时(24.9±3.0)分,临床改善程度达优16例,良6例,可2例,平均改善率79.5%.结论 改良TLIF扩大了手术适应证,贯彻了TLIF技术的设计思想和微创理念,使操作更加简单、安全,用于下腰椎退变性疾患的治疗效果满意.%Objective To analyze the clinical effects Of modified transforaminal lumbar interbody fusion (TLIF)for the treatment of lumbar degenerative disease. Mothods 24 patients with lumbar degenerative disease (L3-S1) were treated by modified TLIF. There were 14 males and 10 females with an average age of 64.6years(56~78years). A total of 40 levels were fused, including 8 cases of single level and 16 cases of double levels. The results of preoperative diagnosis were lumbar degenerative spondylolisthesis with stenosis (6cases), isthmic spondylolisthesis (4cases), degenerative lumbar stenosis (10cases), huge herniated disc with segmental instability (4cases). During the modified TLIF procedure, total inferior facet process and inner half summit of superior facet process of TLIF side were resected to make the

  8. Design of the PROCON trial : a prospective, randomized multi-center study comparing cervical anterior discectomy without fusion, with fusion or with arthroplasty

    NARCIS (Netherlands)

    Bartels, R.H.M.A.; Donk, R.; Wilt, G.J. van der; Grotenhuis, J.A.; Venderink, D.

    2006-01-01

    BACKGROUND: PROCON was designed to assess the clinical outcome, development of adjacent disc disease and costs of cervical anterior discectomy without fusion, with fusion using a stand alone cage and implantation of a Bryan's disc prosthesis. Description of rationale and design of PROCON trial and d

  9. Wiltse入路微创TLIF治疗腰椎间盘突出疗效观察%Observation of lumbar disc herniation treated with minimally invasive transforaminal lumbar interbody fusion (TLIF) through Wiltse approach

    Institute of Scientific and Technical Information of China (English)

    贾红伟; 马文海; 胡艳军; 任志强; 李艳军; 吴超; 韩哲

    2014-01-01

    Objective To evaluate the efficacy of transforaminal lumbar interbody fusion combining contralateral percutaneous pedicle screw for degenerative lumbar disc herniation by Wiltse approach. Methods We studied 40 patients affected by lumbar disc herniation underwent transforaminal lumbar interbody fusion combining contralateral percutaneous pedicle screw ifxation by Wiltse approach in our hospital from June 2009 until December 2012 retrospectively. Clinical and radiographic evaluation were carried out preoperatively and following surgery. Clinical outcome was assessed using the Visual Analog Scale scores (VAS) and The Japanese Orthopaedic Association (JOA) scores. Results The average follow-up time was fourteen months, the average blood loss was three hundreds twenty-six milliliter, the difference of postoperative VAS score and JOA score comparing with preoperative was statistically significant(P<0.01). All screws showed very good position by photos. Bone fusion was considered as solid in forty patients at postoperative 12 months (100%). Conclusion Transforaminal lumbar interbody fusion using percutaneous pedicle screw ifxation by Wiltse approach is a valid and safe treatment of degenerative lumbar disc herniation.%目的:评估Wiltse 入路(后旁正中入路)经椎间孔椎间融合结合对侧经皮椎弓根螺钉治疗退变性腰间盘突出的有效性。方法回顾性研究2009年6月至2012年12月应用Wiltse 入路经椎间孔椎间融合结合对侧经皮椎弓根螺钉固定治疗的40例腰椎间盘突出患者,术前术后进行临床及影像学评估,临床结果应用疼痛模拟视觉评分(VAS)、日本骨科协会(JOA)评分进行评估。结果患者平均随访14个月,平均失血326 mL,术后VAS评分、JOA评分较术前比较差异具有统计学意义(P<0.01),影像学显示所有椎弓根螺钉位置良好,术后12个月40例患者获得良好的融合(100%)。结论Wiltse入路经椎间

  10. Anterior cervical discectomy and fusion: Comparison of titanium and polyetheretherketone cages

    OpenAIRE

    Cabraja Mario; Oezdemir Soner; Koeppen Daniel; Kroppenstedt Stefan

    2012-01-01

    Abstract Background Titanium (TTN) cages have a higher modulus of elasticity when compared with polyetheretherketone (PEEK) cages. This suggests that TTN-cages could show more frequent cage subsidence after anterior cervical discectomy and fusion (ACDF) and therefore might lead to a higher loss of correction. We compared the long term results of stand-alone PEEK- and TTN-cages in a comparable patient collective that was operated under identical operative settings. Methods From 2002 to 2007 15...

  11. 单侧椎间融合内固定治疗腰椎间盘突出症的手术效果%Surgical Effect of Unilateral Pedicle Screw Fixation and Lumbar Interbody Fusion in the Treatment of Lumbar Disc Herniation

    Institute of Scientific and Technical Information of China (English)

    李开雄; 邵玉凯; 郑晓刚; 郭金元; 肖卫; 欧艳春

    2016-01-01

    目的 分析椎间盘突出症椎间融合后单侧内固定的手术效果 .方法 随机选取2007年8月—2014年12月收治的腰椎间盘突出症患者68例,均给予椎间植骨融合术治疗,随机分为单侧内固定治疗的观察组(34例)和双侧内固定治疗的对照组(34例),观察与对比两组患者手术治疗情况. 结果 与对照组比较,观察组患者的手术时间、术中出血量 、术后引流量均低于对照组,差异有统计学意义(P<0.05);术后二组患者的椎间隙曲度、融合率以及JOA评分、MACMAB疗效评定的差异均无统计学意义. 结论 研究表明,单侧椎间融合内固定治疗手术创伤小,可取得与双侧手术相当的近远期疗效.%Objective To analyze the surgical effect of unilateral pedicle screw fixation and lumbar interbody fusion in the treatment of lumbar disc herniation. Methods 68 patients with lumbar disc herniation admitted from August 2007 to De-cember 2014 were randomly divided into the observation group and the control group with 34 cases in each. The observation group were treated by the unilateral pedicle screw fixation and lumbar interbody fusion, while the control group were treated by bilateral pedicle screw fixation and lumbar interbody fusion. And the surgical treatment effect of the two groups was ob-served and compared. Results Compared to the control group, the observation group had shorter operative time, less intra-operative blood loss and less postoperative drainage, the differences were statistically significant (P<0.05). The differences in intervertebral curvature, fusion rate, JOA score and result of MACMAB between the groups after surgery were not statistical-ly significant. Conclusion The study shows that for the treatment of lumbar disc herniation, unilateral pedicle screw fixation and lumbar interbody fusion have smaller trauma, but can obtain the same short-term and long-term effects as bilateral pedicle screw fixation and lumbar interbody fusion.

  12. Artrodese cervical anterior em três e quatro níveis com dispositivo intersomático não associado à placa cervical Artrodesis cervical anterior en tres y cuatro niveles con dispositivo intersomático no asociado a placa cervical Anterior cervical arthrodesis for three and four levels using stand-alone interbody cages without cervical plates

    OpenAIRE

    Marcel Luiz Benato; Ed Marcelo Zaninell; Xavier Soler i Graells; Marcos Andre Sonagli

    2009-01-01

    OBJETIVO: avaliar a taxa de consolidação em pacientes submetidos à artrodese cervical anterior de três e quatro níveis utilizando dispositivo intersomático não associado à placa cervical no sexto mês de pós-operatório. MÉTODOS: no período de Novembro de 2005 a Julho de 2008, 20 pacientes foram submetidos ao tratamento cirúrgico proposto. Os critérios de inclusão foram: diagnóstico clínico e por imagem de doença discal degenerativa cervical em três ou quatro níveis; dor axial e/ou irradiada co...

  13. Clinical curative effect of modified posterior lumbar interbody fusion%改良腰椎后路椎体间植骨融合术的临床疗效分析

    Institute of Scientific and Technical Information of China (English)

    王静成; 蒋朝勇; 杨建东

    2012-01-01

    Objective To evaluate the clinical outcome o[ modified posterior lumbar interbody fusion (PLIF) and transforaminal lumbar interbody fusion (TLIF) with pedicel screw system for several lumbar degenerative disease. Methods From January 2008 to June 2009, 52 patients with lumbar spine of degenerative disease were divided into modified PLIF group ( n = 30) and TLIF group (n =22). The clinical outcome and fusion rate in these two groups were compared. Results All patients had primary healing incision. There was no significant difference in clinical curative effect and postoperative complications between the two groups (P > 0. 05 ) . Conclusion Modified PLIF can reduce the postoperative complications, improve the excellent rate and success rate, reduce the postoperative overhaul rate. It's a safe, reliable and feasible method.%目的 对比研究改良腰椎后路椎体间植骨融合术(PLIF)与经椎间孔入路腰椎椎间植骨融合术(TLIF)治疗腰椎退行性疾病的临床疗效.方法 选择本院2008年1 月-2009年6月收治的52例腰椎退行性疾病患者,随机分为改良PLIF组30例及TLIF组22例,对比2组患者术前、术后第1周,术后第6、12个月腰、腿视觉模拟评分(VAS)及日本骨科学会(JOA)评分,以及术后并发症情况.结果 52例患者切口均一期愈合.2组患者临床疗效及术后并发症发生率无显著差异(P>0.05).结论 改良PLIF减少了术后并发症,提高了手术优良率和手术成功率,且降低了术后翻修率,是一种安全、可靠和可行的方法.

  14. The Use of Bone Morphogenetic Protein in Pediatric Cervical Spine Fusion Surgery: Case Reports and Review of the Literature.

    Science.gov (United States)

    Molinari, Robert W; Molinari, Christine

    2016-02-01

    Study Design Case report. Objective There is a paucity of literature describing the use of bone graft substitutes to achieve fusion in the pediatric cervical spine. The outcomes and complications involving the off-label use of bone morphogenetic protein (BMP)-2 in the pediatric cervical spine are not clearly defined. The purpose of this article is to report successful fusion without complications in two pediatric patients who had instrumented occipitocervical fusion using low-dose BMP-2. Methods A retrospective review of the medical records was performed, and the patients were followed for 5 years. Two patients under 10 years of age with upper cervical instability were treated with occipitocervical instrumented fusion using rigid occipitocervical fixation techniques along with conventionally available low-dose BMP-2. A Medline and PubMed literature search was conducted using the terms "bone morphogenetic protein," "BMP," "rh-BMP2," "bone graft substitutes," and "pediatric cervical spine." Results Solid occipitocervical fusion was achieved in both pediatric patients. There were no reported perioperative or follow-up complications. At 5-year follow-up, radiographs in both patients showed successful occipital cervical fusion without evidence of instrumentation failure or changes in the occipitocervical alignment. To date, there are few published reports on this topic. Complications and the appropriate dosage application in the pediatric posterior cervical spine remain unknown. Conclusions We describe two pediatric patients with upper cervical instability who achieved successful occipital cervical fusion without complication using off-label BMP-2. This report underscores the potential for BMP-2 to achieve successful arthrodesis of the posterior occipitocervical junction in pediatric patients. Use should be judicious as complications and long-term outcomes of pediatric BMP-2 use remain undefined in the existing literature. PMID:26835215

  15. Intertransverse lumbar interbody fusion: A biomechanical in vitro study%腰椎横突间入路椎体间融合术的生物力学评价

    Institute of Scientific and Technical Information of China (English)

    汤俊君; 王新伟; 袁文; 董军; 顾韬

    2008-01-01

    目的 观察腰椎横突间入路椎体间融合术(ILIF)及附加椎弓根钉固定后的生物力学稳定性.方法 采用小牛脊柱运动节段标本12具,依序进行不同处理后分为以下7组:(1)正常对照组(IS);(2)左侧小关节切除+椎间融合器植入组(TLIF);(3)TLIF附加同侧椎弓根钉固定组;(4)TLIF附加双侧椎弓根钉固定组;(5)左侧横突间入路椎间融合器植入组(ILIF);(6)ILIF附加同侧椎弓根钉固定组;(7)ILIF附加双侧椎弓根钉固定组.分别测试各组在轴向压缩、前屈、后伸、左右侧屈时的载荷-应变、载荷-位移变化以及轴向刚度和双向扭转稳定性等生物力学指标,并进行统计学比较.结果 所有生物力学指标中ILIF组稳定性均大于TLIF组(P0.05). 结论 ILIF手术生物力学稳定性优于TLIF手术;ILIF附加同侧椎弓根钉固定与附加双侧椎弓根钉固定生物力学稳定性相当,使用ILIF术式附加侧同椎弓根螺钉固定,可提供较好的即刻稳定性.%Objective To assess the relative stability and kinematics of the lumbar segmental stiffness among intertransverse lumbar interbody fusion (ILIF) with or without transpedicular screw rod fixation and transforaminar lumbar interbody fusion (TLIF) with or without transpedicular screw rod fixation.Methods Twelve fresh frozen bovine lumbar functional spinal units (FSU) were prepared for biomechanical test.According to the different treatments,the specimens were divided into 7 groups: (1) intact specimens (IS);(2) specimens were treated by left unilateral facetectomy and had homolateral anatomical threaded cages inserted (TLIF);(3) TLIF with homolateral pedicle screw fixation (TLIF+HPSF);(4) TLIF with bilateral pedicle screw fixation (TLIF+BPSF);(5) specimens had anatomical threaded cages inserted on the left by intertransverse process approach (ILIF);(6) ILIF with homolateral pedicle screw fixation (ILIF+HPSF);(7) ILIF with bilateral pedicle screw fixation (ILIF+BPSF).Data were

  16. BMP-4 Polymorphisms in the Susceptibility of Cervical Spondylotic Myelopathy and its Outcome after Anterior Cervical Corpectomy and Fusion

    Directory of Open Access Journals (Sweden)

    Dawei Wang

    2013-07-01

    Full Text Available Background: To investigate the association between single nucleotide polymorphisms (SNPs of bone morphogenic proteins-4 (BMP-4 gene and the susceptibility of cervical spondylotic myelopathy (CSM and its outcome after surgical treatment. Method: A total of 499 patients with CSM and 602 healthy volunteers were recruited. 425 CSM patients received anterior cervical corpectomy and fusion (ACF and were follow-up until 12 months. The SNPs of BMP-4 were determined. Results: For 6007C > T polymorphism, the cases had a significant lower prevalence of TT genotype than controls. With the CC genotype as reference, the TT genotype carriages significantly influence the CSM risk. The T allele carriage represented a higher risk for CSM as well. The TT of 6007C>T polymorphisms is also associated with higher chance to gain improvement from ACF surgery. The T allele carriage of 6007C>T had markedly higher chance to have a better post-operative outcome compared with C allele carriage. The genotype and allele distributions of -5826G>A polymorphism did not show positive association with risk and outcome of CSM in this study. Conclusion: BMP-4 genetic polymorphisms may be used as a molecular marker for the CSM susceptibility and its postoperative outcome in those underwent surgical treatment.

  17. Design of Lamifuse: a randomised, multi-centre controlled trial comparing laminectomy without or with dorsal fusion for cervical myeloradiculopathy

    Directory of Open Access Journals (Sweden)

    Grotenhuis J André

    2007-11-01

    Full Text Available Abstract Background laminectomy is a valuable surgical treatment for some patients with a cervical radiculomyelopathy due to cervical spinal stenosis. More recently attention has been given to motion of the spinal cord over spondylotic spurs as a cause of myelopathic changes. Immobilisation by fusion could have a positive effect on the recovery of myelopathic signs or changes. This has never been investigated in a prospective, randomised trial. Lamifuse is an acronyme for laminectomy and fusion. Methods/Design Lamifuse is a multicentre, randomised controlled trial comparing laminectomy with and without fusion in patients with a symptomatic cervical canal stenosis. The study population will be enrolled from patients that are 60 years or older with myelopathic signs and/or symptoms due to a cervical canal stenosis. A kyphotis shape of the cervical spine is an exclusion criterium. Each treatment arm needs 30 patients. Discussion This study will contribute to the discussion whether additional fusion after a cervical laminectomy results in a better clinical outcome. ISRCT number ISRCTN72800446

  18. Langerhans cell histiocytosis causing cervical myelopathy in a child.

    Science.gov (United States)

    Jang, Kun Soo; Jung, Youn Young; Kim, Seok Won

    2010-06-01

    Langerhans cell histiocytosis (LCH), a disorder of the phagocytic system, is a rare condition. Moreover, spinal involvement causing myelopathy is even rare and unusual. Here, we report a case of atypical LCH causing myelopathy, which was subsequently treated by corpectemy and fusion. A 5-year-old boy presented with 3 weeks of severe neck pain and limited neck movement accompanying right arm motor weakness. CT scans revealed destruction of C7 body and magnetic resonance imaging showed a tumoral process at C7 with cord compression. Interbody fusion using cervical mesh packed by autologus iliac bone was performed. Pathological examination confirmed the diagnosis of LCH. After the surgery, the boy recovered from radiating pain and motor weakness of right arm. Despite the rarity of the LCH in the cervical spine, it is necessary to maintain our awareness of this condition. When neurologic deficits are present, operative treatment should be considered. PMID:20617093

  19. Anterior Cervical Spinal Surgery for Multilevel Cervical Myelopathy.

    OpenAIRE

    Jung-Ju Huang; Lih-Huei Chen; Chi-Chien Niu; Tsai-Sheng Fu; Po-Liang Lai; Wen-Jer Chen

    2004-01-01

    Background: In multilevel spinal cord compression caused by cervical spondylosis, surgeonsface the choice of performing a posterior route as a laminectomy orlaminoplasty, or an anterior route as multiple adjacent interbody decompressionsor corpectomies. The anterior cervical operation is not considered bysome clinicians because of concerns about complications and the complexityof multilevel anterior cervical surgery.Methods: In this retrospective study, 14 patients with multilevel cervical sp...

  20. Open versus minimally invasive transforaminal lumbar interbody fusion for single segment degenerative lumbar disease:A Meta-analysis%开放与微创经椎间孔椎体间融合治疗单节段退行性腰椎疾病的Meta分析★

    Institute of Scientific and Technical Information of China (English)

    王银; 陈根元; 胡龙; 萧文耀; 王建民

    2013-01-01

      背景:微创经椎间孔椎体间融合技术采用微小切口经可扩张通道进行,与开放经椎间孔椎体间融合技术相比,微创技术视野小,操作更为精细,对周围组织的损伤较小,有利于恢复。  目的:对微创经椎间孔椎体间融合技术与开放经椎间孔椎体间融合技术治疗单节段退行性腰椎疾病的疗效及临床价值进行评价。  方法:检索2005至2012年间 Cochrane library、PubMed、Embase、SCI、中国生物医学文献数据库、中国知网和万方数据库,手工检索相关文献的参考文献及4种中文主要骨科杂志,纳入以单节段退行性腰椎疾病为研究对象,比较微创与开放经椎间孔椎体间融合技术治疗的随机对照试验,前瞻性队列研究及回顾性队列研究,严格评价纳入研究的方法学质量并提取资料,用 Cochrane 协作网提供的Revman5.1进行 Meta 分析。  结果与结论:经过筛选纳入7个研究(856例患者)。7个研究圴选用手术时间作为观察指标,结果显示微创手术的手术操作时间与开放手术比较差异无显著性意义(P=0.11);6个研究选用术中出血量作为观察指标,结果显示微创手术的术中出血量明显少于开放手术(P OBJECTIVE: To evaluate the surgical outcome and clinicaI value between minimal y invasive and open transforaminal lumbar interbody fusion in treatment of single segment degenerative lumbar disease. METHODS: The Cochrane library, PubMed database, Embase database, SCI database, CNKI database, Wanfang database and Chinese Biomedical database were searched for control ed trials, prospective cohort study and retrospective cohort study on the comparison between minimal y invasive and open transforaminal lumbar interbody fusion in treatment of degenerative lumbar disease. Furthermore, we also manual y searched the relevant references and four Chinese orthopedic journals. Methodology quality of the

  1. 腹腔镜辅助腰椎前路椎间融合术治疗腰椎退变性疾病%Clinical application of anterior lumbar interbody fusion assisted with laparoscopic

    Institute of Scientific and Technical Information of China (English)

    王文军; 贺更生; 晏怡果; 姚女兆; 王麓山; 王程; 韩东

    2011-01-01

    目的 探讨腹腔镜辅助腰椎前路椎间融合术治疗腰椎退变性疾病的疗效.方法 2006年1月至2009年6月腰椎退变性疾病患者37例行腹腔镜辅助腰椎前路椎间融合,男22例,女15例;年龄16~55岁,平均43.7岁.全部病例行血管造影三维CT检查、17例行椎间盘造影检查,确定责任椎间盘为L5S121例,L4-5 11例,L3-4 2例,L2-3 2例,L1-2 1例.29例经腹腔人路、8例经腹膜后入路行椎间盘切除及椎间融合器融合,3例以骨盆重建钛板固定.术后3、6、12个月通过X线或CT观察植骨融合情况,3个月时采用中华医学会骨科学分会脊柱学组腰背痛手术评分评价疗效.结果 手术时间60~140 min,平均100 min;术中出血50~300 ml,平均120 ml;住院时间7~12d,平均8d.2例经腹腔入路患者出现麻痹性肠梗阻.全部病例随访6~35个月,平均18.7个月.疗效为优23例、良11例、差3例,优良率91.9%(34/37).23例于术后3个月、12例于术后6个月植骨融合;2例术后6个月时椎间前缘高度丢失1.3mm和1.9 mm,无明显不适症状,术后12个月植骨融合.无内植物松动、脱落等并发症.结论 腹腔镜辅助腰椎前路椎间融合术创伤小、卧床时间短、并发症少.经腹腔入路术后肠梗阻相对多见.在选择手术入路时应考虑术者经验和下腰椎前方大血管的解剖位置.%Objective To evaluate the clinical outcomes of anterior lumbar discectomy and interbody fusion with cage under laparoscopic assistant.Methods From January 2006 to June 2009,37 cases with degenerative low back pain were entered the study,including 22 males and 15 females with an average age of 43.7 years (range,16-55).The responsible discs were determined according to the three dimensional computed tomography of artery and vein angiography of anterior lumbosacral spine and discography,including L5S1 in 21 cases,L4-5 in 11,L3-4 in 2,L2-3 in 2,and L1-2 in 1.All cases underwent anterior lumbar discectomy and interbody

  2. Lumbar interbody fusion vs dynamic stabilization system for degenerative lumbar disease%腰椎椎间融合术与动态固定术治疗腰椎退行性疾病的临床评价

    Institute of Scientific and Technical Information of China (English)

    马辉; 李忠海; 朱晓东; 白玉树; 王传峰; 吴大江; 陈誉; 李明

    2011-01-01

    目的 通过比较分析腰椎椎间融合术与动态固定术治疗腰椎退行性疾病的临床疗效和术后并发症,探讨腰椎退行性疾病治疗方法的合理选择.方法 2009年1月~2010年12月,选择32例腰椎退行性疾病(L4/L5)患者,按配对设计分为对照组和治疗组,对照组16例患者均行椎弓根螺钉固定并单枚融合器置入;治疗组16例患者行常规椎板切除减压、髓核摘除和Isobar动态固定.比较观察2组病例的治疗效果、手术时间、出血量、手术并发症等.治疗效果评价采用Oswestry功能障碍指数(Oswestry disability index,ODI)及疼痛视觉模拟量表(visual analogue scale,VAS)评分,手术邻近节段(L3/L4和L5/S1)及腰椎(L2~S1)的活动度(range of motion,ROM)采用过伸过屈动力侧位X线片检查进行评价.结果 所有患者均获6~24个月的随访,平均15.8个月.与术前相比,2组患者术后症状均有明显改善,术后ODI及VAS评分与术前相比差异有统计学意义(P0.05);2组均未出现内固定相关并发症;2组术后邻近节段(L3/L4和L5/S1)的ROM与术前相比差异无统计学意义(P>0.05).腰椎(L2~S1)的ROM,融合组较术前显著下降,差异有统计学意义(P0.05).结论 腰椎椎间融合术与Isobar动态固定术治疗单节段腰椎退变性疾病均可取得满意的短期临床疗效,但理论上动态固定技术内固定失败的风险高于椎间融合术,故采用动态固定技术治疗腰椎退变性疾病应慎重.%Objective To assess the clinical effectiveness and postoperative complications of lumbar interbody fusion and dynamic stabilization system( the Isobar system ) for degenerative lumbar disease, in an attempt to explore an optimal surgical procedure. Methods From January 2009 to December 2010, 32 degenerative disease ( L4/L5 ) cases were randomly and equally assigned to an experimental group of decompression and dynamic stabilization with Isobar system ( n = 16 ) and a control group of

  3. Design of the PROCON trial: a prospective, randomized multi – center study comparing cervical anterior discectomy without fusion, with fusion or with arthroplasty

    Directory of Open Access Journals (Sweden)

    Grotenhuis J André

    2006-11-01

    Full Text Available Abstract Background PROCON was designed to assess the clinical outcome, development of adjacent disc disease and costs of cervical anterior discectomy without fusion, with fusion using a stand alone cage and implantation of a Bryan's disc prosthesis. Description of rationale and design of PROCON trial and discussion of its strengths and limitations. Methods/Design Since proof justifying the use of implants or arthroplasty after cervical anterior discectomy is lacking, PROCON was designed. PROCON is a multicenter, randomized controlled trial comparing cervical anterior discectomy without fusion, with fusion with a stand alone cage or with implantation of a disc. The study population will be enrolled from patients with a single level cervical disc disease without myelopathic signs. Each treatment arm will need 90 patients. The patients will be followed for a minimum of five years, with visits scheduled at 6 weeks, 3 months, 12 months, and then yearly. At one year postoperatively, clinical outcome and self reported outcomes will be evaluated. At five years, the development of adjacent disc disease will be investigated. Discussion The results of this study will contribute to the discussion whether additional fusion or arthroplasty is needed and cost effective. Trial registration Current Controlled Trials ISRCTN41681847

  4. 椎间盘镜下可膨胀性椎间融合器B-Twin椎间融合术治疗退变失稳性腰椎间盘突出症%Using of Microendoscopic Decompression and Interbody Fusion with B-Twin to Treat the Unstable Herniation of Lumbar Disc with Degeneration

    Institute of Scientific and Technical Information of China (English)

    胡安文; 罗光平; 肖业生; 杨长远

    2011-01-01

    Objective To investigate the efficacy of microendoscopic decompression and interbody fusion with B-twin to treat the patients with degenerative lumbar disc herniation with a unstable spine. Methods From June 2005 to June 2008, 32 cases of unstable herniation of the lumbar disc with degeneration received microendoscopic decompression and interbody fusion with expandable spinal spacer of B-Twin. Results Thirty two case VAS pain score decreased from 8.7±0.3 to 2.3±1.7 (t=7.580,P<0.01). The patients were followed up for a mean of 25±3.3 months, According Suk judgement criterion, 1-year fusion rate was 93.8% (30/32), and the 2-year fusion rate was was 96.9%(31/32).No patients showed subsidence of the B-Twin. Conclusion Microendoscopic decompression and interbody fusion with B-Twin is minimal invasive and higher interbody fusion and can obtain a satisfactory outcome.%目的 探讨后路显微椎间盘镜下可膨胀性椎间融合器B-Twin植入椎间融合术治疗腰椎退变失稳性椎间盘突出症的临床疗效.方法 2005年6月~2008年6月,对32例腰椎退变失稳性巨大型椎间盘突出症行后路显微椎间盘镜联合可膨胀性椎间融合器B-Twin植入椎间融合术.结果 术后1周VAS疼痛评分由术前(8.7±0.3)分降至术后(2.3±1.7)分(P<0.01).随访时间平均(25±3.3)个月,植骨融合率采用Suk标准判断:1年融合率为93.8%,2年融合率为96.9%.结论 后路显微椎间盘镜联合可膨胀性椎问融合器B-Twin植入椎间融合术治疗腰椎退变失稳性巨大型椎间盘突出症创伤小、植骨融合率高、临床效果满意.

  5. Analytical comparison study of the clinical and radiological outcome of spine fixation using posterolateral, posterior lumber interbody and transforaminal lumber interbody spinal fixation techniques to treat lumber spine degenerative disc disease

    OpenAIRE

    Al Barbarawi, Moh’d M; Audat, Ziad M; Allouh, Mohammed Z.

    2015-01-01

    Background Degenerative disc disease is a common cause of chronic and disabling back pain that requires surgical intervention, posterolateral and posterior instrumental fixation (PLF), posterior lumber interbody fusion (PLIF) and transforaminal lumber interbody fusion (TLIF) are the techniques used to deal with such a problem. Objective To compare the clinical and radiological outcome of the variable surgical techniques used to deal with Lumber degenerative disc disease and to recommend the t...

  6. Long term results of anterior corpectomy and fusion for cervical spondylotic myelopathy.

    Directory of Open Access Journals (Sweden)

    Rui Gao

    Full Text Available BACKGROUND: Results showed good clinical outcomes of anterior corpectomy and fusion (ACCF for patients with cervical spondylotic myelopathy (CSM during a short term follow-up; however, studies assessing long term results are relatively scarce. In this study we intended to assess the long term clinical and radiographic outcomes, find out the factors that may affect the long term clinical outcome and evaluate the incidence of adjacent segment disease (ASD. METHODS: This is a retrospective study of 145 consecutive CSM patients on ACCF treatment with a minimum follow-up of 5 years. Clinical data were collected from medical and operative records. Patients were evaluated by using the Japanese Orthopedic Association (JOA scoring system preoperatively and during the follow-up. X-rays results of cervical spine were obtained from all patients. Correlations between the long term clinical outcome and various factors were also analyzed. FINDINGS: Ninety-three males and fifty-two females completed the follow-up. The mean age at operation was 51.0 years, and the mean follow-up period was 102.1 months. Both postoperative sagittal segmental alignment (SSA and the sagittal alignment of the whole cervical spine (SACS increased significantly in terms of cervical lordosis. The mean increase of JOA was 3.8 ± 1.3 postoperatively, and the overall recovery rate was 62.5%. Logistic regression analysis showed that preoperative duration of symptoms >12 months, high-intensity signal in spinal cord and preoperative JOA score ≤ 9 were important predictors of the fair recovery rate (≤ 50%. Repeated surgery due to ASD was performed in 7 (4.8% cases. CONCLUSIONS: ACCF with anterior plate fixation is a reliable and effective method for treating CSM in terms of JOA score and the recovery rate. The correction of cervical alignment and the repeated surgery rate for ASD are also considered to be satisfactory.

  7. Posterior pedicle screw fixation and interbody fusion in the treatment of recurrent lumbar disc herniation:an evaluation of vertebral stability%后路钉棒内固定椎间融合治疗复发性腰椎间盘突出症:椎体稳定性评价

    Institute of Scientific and Technical Information of China (English)

    刘凤松; 王凯; 景成伟; 张亮; 刘宾; 杨亚林

    2014-01-01

    BACKGROUND:Discectomy is an important therapy for lumbar disc herniation, but a smal number of patients undergoing discectomy wil relapse. OBJECTIVE:To investigate the spinal stability fol owing posterior pedicle screw fixation combined with interbody fusion cage for treatment of recurrent lumbar disc herniation. METHODS:Twenty-six patients with recurrent lumbar disc herniation from January 2007 to December 2011 were enrol ed and subjected to posterior pedicle screw fixation combined with interbody fusion cage. Pain relief and lumbar stability were observed postoperatively. We analyzed the spinal stability in recurrent lumbar disc herniation patients after posterior pedicle screw fixation combined with interbody fusion cage depending on literature search. RESULTS AND CONCLUSION:Al the 26 patients were fol owed up for 12-36 months. After treatment, al patients effectively al eviated the symptoms of low back pain, and lumbar interbody fusion was good, with a good rate of 96.2%. There was no pedicle screw loosening, broken, non-fusion phenomenon. Posterior decompression and interbody fusion cage combined with posterior pedicle screw fixation for recurrent lumbar disc herniation, characterized as fast symptom relief, strong fixation, exact interbody fusion exact, is an ideal treatment for recurrent lumbar disc herniation.%背景:腰椎间盘突出症治疗的重要方法是椎间盘切除,但有少部分患者会出现复发现象。  目的:探讨后路椎弓根钉棒内固定联合cage植入椎间融合治疗复发性腰椎间盘突出症后的脊柱稳定性。  方法:选择2007年1月至2011年12月复发性腰椎间盘突出症患者26例,应用后路减压cage植入椎间融合加钉棒系统内固定治疗复发性腰椎间盘突出症进行再手术治疗,观察患者治疗后疼痛症状缓解情况以及腰椎稳定性。通过数据库文献检索的方法分析后路钉棒内固定椎间融合治疗复发性腰椎间盘突出症的椎

  8. Commentary on article: Laminoplasty versus laminectomy and fusion for multilevel cervical myelopathy: A meta-analysis of clinical and radiological outcomes by Chang-Hyun Lee et al

    OpenAIRE

    Nancy E Epstein

    2015-01-01

    Background: This is a commentary on the article laminoplasty versus laminectomy and fusion (LF) for multilevel cervical myelopathy: A meta-analysis of clinical and radiological outcomes by Chang-Hyun Lee et al. Here, the authors utilized seven studies to compare the efficacy of cervical expansive laminoplasty (EL) versus laminectomy and fusion (LF) to address three or more level multilevel cervical spondylotic myelopathy (CSM). Both procedures led to similar degrees of neurological recovery a...

  9. Cause analysis and treatment strategy of cage retropulsion after lumbar interbody fusion%腰椎融合器后移的原因分析及处理对策

    Institute of Scientific and Technical Information of China (English)

    王洪立; 姜建元; 吕飞舟; 马晓生; 夏新雷; 王立勋

    2012-01-01

    目的 探讨腰椎融合术后融合器后移的原因及临床处理对策.方法 回顾性分析2005年12月至2011年10月腰椎融合术后融合器后移至椎管的11例患者的完整资料,男7例,女4例;初次手术时年龄36~78岁,平均52.3岁.6例患者在初次手术后0.5~3个月,平均2.1个月椎间融合器发生后移(早期移位),5例患者在初次手术后14~36个月,平均24.8个月发生后移(晚期移位).分析11例患者融合器后移发生原因,根据患者是否伴腰痛及下肢症状而行保守或手术治疗.结果 早期移位发生原因与椎间隙处理不当、髓核残留过多、软骨终板刮除不足、融合器型号选择过小、融合器植入位置不当、固定强度不足等相关.晚期移位发生原因与手术方案选择不当、多节段融合固定、术前椎间节段存在不稳定、高龄、骨质疏松及合并糖尿病等有关.11例患者均获得随访,随访时间6~72个月,平均34个月;3例经保守治疗、8例接受翻修手术治疗均获得临床愈合.随访期间该组病例临床症状无明显加重,影像学随访未发现融合器再次移位、植骨不融合、椎弓根螺钉松动等并发症. 结论 腰椎融合术后融合器后移的发生原因复杂,移位发生时间的不同对移位原因的判断具有一定的临床价值;针对不同的移位原因、临床表现及影像学检查结果选择个性化方案进行治疗.%Objective To investigate causes and treatment strategy of cage retropulsion after lumbar interbody fusion.Methods Data of 11 patients with cage retropulsion after lumbar interbody fusion from December 2005 to October 2011 in our hospital were retrospectively analyzed.There were 7 males and 4 females.Their age ranged from 36 to 78 years (average,52.3 years) at the time of the primary operation.Six cases occurred cage retropulsion 0.5 to 3 months after the primary operation,while 5 cases occurred cage retropulsion 14 to 36 months after the

  10. The early clinical observation about Dynesys and lumbar interbody fusion in treatment of lumbar degenerative diseases%非融合技术与腰椎融合术治疗腰椎退变性疾病的早期疗效观察

    Institute of Scientific and Technical Information of China (English)

    王孟; 李坤; 王飞; 张元豫

    2012-01-01

    Objective To investigate the difference of early clinical efficacy between Dynesys and lumbar interbody fusion in treatment of lumbar degenerative diseases. Methods Clinical data of 36 patients under two methods treatment of lumbar degenerative diseases with 18 examples in each were retrospectively analyzed. Patients were observed blood loss, VAS, ODI index, the rate for short-term excellent or good relief of symptoms and ROM. Results Two groups of VAS and ODI index had been significantly improved; Dynesys group maintained adjacent segment ROM to its original condition, while instrumented segment ROM decreased; In lumbar interbody fusion group, adjacent segment ROM increased, and instrumented segments fused. Conclusions Dynesys and the lumbar interbody fusion can all take the ideal early curative effect. Dynesys preserve partial ROM ,and prevent accelerated degeneration, which is a desirable method of treatment.%目的 探讨Dynesys和腰椎融合治疗腰椎退行性疾病早期临床疗效.方法 采用两种方法治疗36例腰椎退行性疾病患者,Dynesys组18例,腰椎融合组18例.观察两组手术时间、术中出血量、VAS评分、ODI指数、手术效果优良率及椎间活动度(ROM).结果 两组术后VAS及ODI都得到明显改善;Dynesys组邻近节段ROM维持在原来状态,手术节段ROM减小;腰椎融合组邻近节段ROM增大,手术节段融合.结论 Dynesys与腰椎融合术均可取的理想的早期疗效,Dynesys保持了部分椎间活动度,有利于防止退变加速.

  11. 退变性腰椎管狭窄症的腰后路减压椎间植骨融合术治疗观察%The Treatment Observation of Degenerative Lumbar Spinal Stenosisby Posterior Lumbar Decompression and Interbody Fusion

    Institute of Scientific and Technical Information of China (English)

    赖征文; 李敏; 李平安; 刘云彬

    2011-01-01

    Objective:Observed the treatment effect of degenerative lumbar spinal stenosis by posterior lumbar decompression and interbody fusion.Methods:42 patients admitted to our hospital with degenerative lumbar spinal stenosis were divided into two groups,the control group were taken a simple decompression,the treatment group were taken by lumbar posterior decompression and interbody fusion surgery,compared the efficacy and prognosis of two groups.Results:The treatment group,the three time periods JOA scores are significantly better than the control group,P>0.05.Conclusion:The lumbar posterior decompression and interbody fusion can improve the symptoms,the effect last stability,is a good treatment option.%目的:观察腰后路减压椎间植骨融合术对于退变性腰椎管狭窄症的治疗效果.方法:将本院收治的42例退变性腰椎管狭窄症患者分为两组,对照组采取单纯减压术,治疗组采取经腰后路减压椎间植骨融合术,对比两组的近期疗效及预后情况.结果:治疗组在三个时间段的JOA评分均明显优于对照组,P>0.05.结论:经腰后路减压椎间植骨融合术可有效改善患者的症状,效果持久稳定,是一种良好的治疗选择.

  12. Comparison of inpatient vs. outpatient anterior cervical discectomy and fusion: a retrospective case series

    Directory of Open Access Journals (Sweden)

    Friedman Jonathan A

    2009-03-01

    Full Text Available Abstract Background Spinal surgery is increasingly being done in the outpatient setting. We reviewed our experience with inpatient and outpatient single-level anterior cervical discectomy and fusion with plating (ACDF+P. Methods All patients undergoing single-level anterior cervical discectomy and fusion with plating between August 2005 and May 2007 by two surgeons (RPB or JAF were retrospectively reviewed. All patients underwent anterior cervical microdiscectomy, arthrodesis using structural allograft, and titanium plating. A planned change from doing ACDF+P on an inpatient basis to doing ACDF+P on an outpatient basis was instituted at the midpoint of the study. There were no other changes in technique, patient selection, instrumentation, facility, or other factors. All procedures were done in full-service hospitals accommodating outpatient and inpatient care. Results 64 patients underwent ACDF+P as inpatients, while 45 underwent ACDF+P as outpatients. When outpatient surgery was planned, 17 patients were treated as inpatients due to medical comorbidities (14, older age (1, and patient preference (2. At a mean follow-up of 62.4 days, 90 patients had an excellent outcome, 19 patients had a good outcome, and no patients had a fair or poor outcome. There was no significant difference in outcome between inpatients and outpatients. There were 4 complications, all occurring in inpatients: a hematoma one week post-operatively requiring drainage, a cerebrospinal fluid leak treated with lumbar drainage, syncope of unknown etiology, and moderate dysphagia. Conclusion In this series, outpatient ACDF+P was safe and was not associated with a significant difference in outcome compared with inpatient ACDF+P.

  13. Recurrence of cervical myelopathy secondary to a strut graft fracture 20 years after anterior decompression and fusion: a case report.

    Science.gov (United States)

    Kida, Kazunobu; Takaya, Shogo; Tadokoro, Nobuaki; Kumon, Masashi; Kiyasu, Katsuhito; Kato, Tomonari; Takemasa, Ryuichi; Ikeuchi, Masahiko; Tani, Toshikazu

    2015-08-01

    This study reports on a 70-year-old man with recurrent cervical myelopathy 20 years after anterior decompression and fusion of C4-7 using a free vascularised strut graft. The recurrent myelopathy was secondary to a kyphotic deformity of a fractured graft and residual ossification of the posterior longitudinal ligament with stenosis at C3/4. Intraoperative spinal cord-evoked potentials indicated that spinal cord traction secondary to progressive kyphosis of the cervical spine after the graft fracture was the cause. The patient underwent laminoplasty at C3 and laminectomy at C4 to decompress the stenosis at C3/4 as well as posterior cervical spinal fusion at C3-7 with pedicle screws and a lateral mass screw and a bone graft to prevent further progression of the kyphosis. At postoperative 18 months, the patient's Japanese Orthopaedic Association score had improved to 14 from 8, and he could walk without support. PMID:26321562

  14. Transdural retrieval of a retropulsed lumbar interbody cage: Technical case report.

    Science.gov (United States)

    Zaidi, Hasan Aqdas; Shah, Ashish; Kakarla, Udaya Kumar

    2016-01-01

    The purpose of this case report was to describe a novel method to retrieve a herniated lumbar interbody cage. Transforaminal lumbar interbody fusion (TLIF) is an increasingly popular method of spinal fixation and fusion. Unexpected retropulsion of an interbody is a rare event that can result in intractable pain or motor compromise necessitating surgical retrieval of the interbody. Both anterior and posterior approaches to removing migrated cages may be associated with significant surgical morbidity and mortality. A 60-year-old woman underwent an L4-S1 TLIF coupled with pedicle screw fixation at a previous hospital 5 years prior to admission. She noted sudden-onset bilateral lower extremity weakness and right-sided foot drop. Magnetic resonance imaging and radiographs were notable for purely centrally herniated interbody. A posterior, midline transdural approach was used to retrieve the interbody. Situated in between nerve rootlets to the ventral canal, this virgin corridor allowed us to easily visualize and protect neurological structures while safely retrieving the interbody. The patient experienced an immediate improvement in symptoms and was discharged on postoperative day 3. At 12-month follow-up, she had no evidence of cerebrospinal fluid (CSF) leak and had returned to normal activities of daily living. While the risk of CSF leak may be higher with a transdural approach, we maintain that avoiding unnecessary retraction of the nerve roots may outweigh this risk. To our knowledge, this is the first case report of a transdural approach for the retrieval of a retropulsed lumbar interbody cage. PMID:26889290

  15. MR and CT image fusion of the cervical spine: a noninvasive alternative to CT-myelography

    Science.gov (United States)

    Hu, Yangqiu; Mirza, Sohail K.; Jarvik, Jeffrey G.; Heagerty, Patrick J.; Haynor, David R.

    2005-04-01

    CT-Myelography (CTM) is routinely used for planning surgery for degenerative disease of the spine, but its invasive nature, significant potential morbidity, and high costs make a noninvasive substitute desirable. We report our work on evaluating CT and MR image fusion as an alternative to CTM. Because the spine is only piecewise rigid, a multi-rigid approach to the registration of spinal CT and MR images was developed (SPIE 2004), in which the spine on CT images is first segmented into separate vertebrae, each of which is then rigidly registered with the corresponding vertebra on MR images. The results are then blended to obtain fusion images. Since they contain information from both modalities, we hypothesized that fusion images would be equivalent to CTM. To test this we selected 34 patients who had undergone MRI and CTM for degenerative disease of the cervical spine, and used the multi-rigid approach to produce fused images. A clinical vignette for each patient was created and presented along with either CT/MR fusion images or CTM images. A group of spine surgeons are asked to formulate detailed surgical plans based on each set of images, and the surgical plans are compared. A similar study assessing diagnostic agreement is being performed with neuroradiologists, who also assess the accuracy of registration. Our work to date has demonstrated the feasibility of segmentation and multi-rigid fusion in clinical cases and the acceptability of the questionnaire to physicians. Preliminary analysis of one surgeon's and one neuroradiologist"s evaluation has been performed.

  16. Predictive value of intraoperative nerve monitoring for posterior lumbar interbody fusion%不同术中神经监测方法对后路腰椎椎间融合手术的预测作用

    Institute of Scientific and Technical Information of China (English)

    史图龙; 汪萌; 薛静; 彭江; 薛丽娟; 尚咏

    2015-01-01

    目的 比较体感诱发电位(somatosensory evoked potential,SEP)、运动诱发电位(motor evoked potential,MEP)和肌电图(electromyography,EMG)不同组合监测方式对腰椎后路椎板减压椎弓根螺钉固定椎体融合术(posterior lumbar interbody fusion,PLIF)术后结果的预测作用.方法 回顾性研究空军总医院骨科腰椎后路椎管减压融合术临床资料117例,其中66例行SEP+ EMG监测,51例采用MEP+ EMG监测.根据术中监测情况,并与术后结果疗效进行比较,并行统计学分析.结果 MEP+ EMG组手术时间明显少于SEP+ EMG组(P<0.05).SEP+ EMG组患者中,3例出现假阴性,8例为假阳性,1例出现监测信号引出不满意,共3例出现术后症状加重.在MEP+ EMG组中,2例未能引出信号,其中1例术后症状加重.两组监测方法对术后疗效准确性的比较有统计学意义(P<0.05).结论 MEP+ EMG监测反应灵敏,对腰椎融合术的手术结果及疗效有良好的预测作用,且对手术时间的影响更小.

  17. Long-term results of anterior cervical corpectomy and fusion with nano-hydroxyapatite/polyamide 66 strut for cervical spondylotic myelopathy

    Science.gov (United States)

    Zhang, Yuan; Deng, Xu; Jiang, Dianming; Luo, Xiaoji; Tang, Ke; Zhao, Zenghui; Zhong, Weiyang; Lei, Tao; Quan, Zhengxue

    2016-05-01

    To assess the long-term clinical and radiographic outcomes of anterior cervical corpectomy and fusion (ACCF) with a neotype nano-hydroxyapatite/polyamide 66 (n-HA/PA66) strut in the treatment of cervical spondylotic myelopathy (CSM). Fifty patients with CSM who underwent 1- or 2-level ACCF with n-HA/PA66 struts were retrospectively investigated. With a mean follow-up of 79.6 months, the overall mean JOA score, VAS and cervical alignment were improved significantly. At last follow-up, the fusion rate was 98%, and the subsidence rate of the n-HA/PA66 strut was 8%. The “radiolucent gap” at the interface between the n-HA/PA66 strut and the vertebra was further noted to evaluate the osteoconductivity and osseointegration of the strut, and the incidence of it was 62% at the last follow-up. Three patients suffered symptomatic adjacent segment degeneration (ASD). No significant difference was detected in the outcomes between 1- and 2-level corpectomy at follow-ups. In conclusion, the satisfactory outcomes in this study indicated that the n-HA/PA66 strut was an effective graft for cervical reconstruction. Moreover, the osteoconductivity and osseointegration of the strut is still need to be optimized for future clinical application owing to the notably presence of “radiolucent gap” in present study.

  18. Measuring surgical outcomes in cervical spondylotic myelopathy patients undergoing anterior cervical discectomy and fusion: assessment of minimum clinically important difference.

    Directory of Open Access Journals (Sweden)

    Brenda M Auffinger

    Full Text Available OBJECT: The concept of minimum clinically important difference (MCID has been used to measure the threshold by which the effect of a specific treatment can be considered clinically meaningful. MCID has previously been studied in surgical patients, however few studies have assessed its role in spinal surgery. The goal of this study was to assess the role of MCID in patients undergoing anterior cervical discectomy and fusion (ACDF for cervical spondylotic myelopathy (CSM. METHODS: Data was collected on 30 patients who underwent ACDF for CSM between 2007 and 2012. Preoperative and 1-year postoperative Neck Disability Index (NDI, Visual-Analog Scale (VAS, and Short Form-36 (SF-36 Physical (PCS and Mental (MCS Component Summary PRO scores were collected. Five distribution- and anchor-based approaches were used to calculate MCID threshold values average change, change difference, receiver operating characteristic curve (ROC, minimum detectable change (MDC and standard error of measurement (SEM. The Health Transition Item of the SF-36 (HTI was used as an external anchor. RESULTS: Patients had a significant improvement in all mean physical PRO scores postoperatively (p<0.01 NDI (29.24 to 14.82, VAS (5.06 to 1.72, and PCS (36.98 to 44.22. The five MCID approaches yielded a range of values for each PRO: 2.00-8.78 for PCS, 2.06-5.73 for MCS, 4.83-13.39 for NDI, and 0.36-3.11 for VAS. PCS was the most representative PRO measure, presenting the greatest area under the ROC curve (0.94. MDC values were not affected by the choice of anchor and their threshold of improvement was statistically greater than the chance of error from unimproved patients. CONCLUSION: SF-36 PCS was the most representative PRO measure. MDC appears to be the most appropriate MCID method. When MDC was applied together with HTI anchor, the MCID thresholds were: 13.39 for NDI, 3.11 for VAS, 5.56 for PCS and 5.73 for MCS.

  19. The anatomic study and clinical significance of the modified transforaminal lumbar interbody fusion%改良经椎间孔腰椎椎体间融合术的解剖学研究及临床意义

    Institute of Scientific and Technical Information of China (English)

    姜建元; 马昕; 吕飞舟; 王洪立; 陈文钧; 马晓生; 夏新雷

    2009-01-01

    目的 对传统的经椎间孔腰椎椎体间融合术(TLIF)进行改良并探讨其临床意义.方法 在12具新鲜成人尸体上完成传统后路腰椎椎体间融合(PLW)和THF术式,扩大解剖显露周围结构,根据解剖学研究发现提出改良TLIF手术方式,并在12具新鲜尸体上操作、完成该术式,对其可行性及潜在优势进行分析.结果 前期的解剖学研究发现传统PLIF和TLIF手术在行椎间融合时相应神经根张力较高,存在一定的损伤风险,同时发现在一侧上关节突与棘突及棘间韧带等中间结构之间存在一定的可操作区域.提出了将PLIF工作区域外移,TLIF工作区域内移的改良TLIF手术人路,即:采取后正中入路,保留棘突、椎板上缘、棘上、棘间韧带等后结构,剥离双侧椎旁肌,暴露椎板及关节突关节,不暴露横突,切除一侧下关节突及椎板下2/3(暴露上关节突关节面),单侧斜向处理椎间隙而行椎体间融合.在12具新鲜成人尸体上顺利模拟完成了改良TLIF手术,结果显示该术式具有以下优势:(1)不必暴露横突,保留棘突、椎板上缘、棘上、棘间韧带等后结构,仅咬除一侧下关节突及椎板下2/3;(2)中央管及术侧侧隐窝及神经根管可同时有效减压;(3)斜向处理目标椎间隙,后正中结构的保留有效地限制了对硬膜囊及下位神经根的牵拉,术中无需暴露上位神经根,不易损伤上位神经根.结论 改良TLIF手术入路安全可行,理论上可以有效地降低神经根损伤的发生率,对于绝大多数国人腰椎疾患患者可能是一个较理想的选择.%Objective To put some improvements to the traditional transforaminal lumbar interbody fusion (TLIF) and discuss its clinical significance. Methods Completed the traditional posterior lumbar interbody fusion (PLIF) and TLIF procedure in 12 fresh cadavers, dissect further to expose the surrounding anatomical structures, and put the modified TLIF surgery according to

  20. 上颈椎融合对颈椎活动度的影响%The impact of the upper cervical spine fusion on cervical range of motion

    Institute of Scientific and Technical Information of China (English)

    袁伟; 朱悦; 崔璀

    2012-01-01

    目的 探讨上颈椎融合对颈椎活动功能的影响,并评估颈椎活动度测量仪(cervical range of motion device,CROM)的可靠性.方法 我科于2010年7月至2011年10月对收治的14例上颈椎疾病患者使用CROM仪测量,其中5例为颈枕融合,2例寰枢椎融合,7例采用Halo架非融合治疗后2个月及6个月左右颈椎前屈、后伸、左右侧弯、左右旋转主动活动度,并与15例健康志愿者颈椎活动度进行比较,分析术后颈椎活动度丢失情况;使用CROM仪重复测量健康志愿者颈椎活动度并采用组间相关系数(intraclass correlation coefficients,ICC)来评价CROM仪的测量者内可靠性.结果 术后6个月随访时颈椎活动度六个方向中的三个方向:颈椎前屈、左旋转及右旋转,融合组与非融合组相比有显著降低(P<0.05),与正常组相比则在六个方向均有显著性差异(P<0.05).融合组中颈枕融合较寰枢椎融合在颈椎前屈、左右旋转活动上有显著性降低(P<0.05),术后第6个月随访各组颈椎活动度较3个月随访时均有一定程度的增加.CROM仪测量颈椎六个方向的活动度测量者内ICC均在0.91以上,有较高的可靠性.结论 上颈椎融合使颈椎活动范围显著性减小,对颈椎前屈、旋转功能影响最大.此外,CROM仪是一种可靠的颈椎活动度测量工具.%Objective To investigate the impact of the upper cervical spine fusion on cervical range of motion (CROM) and to evaluate the reliability of the CROM device. Methods From July 2010 to October 2011, 14 patients with upper cervical disease were adopted by our department and treated with cervical spine fusion or non-fusion, among whom there were 5 cases of cervicooccipital fusion, 2 cases of atlantoaxial fusion and 7 cases of Halo-vest treatment. The cervical flexion, backward extension, left and right lateral bending and rotation of all patients were measured by the CROM device about 2 months and 6 months after surgery

  1. 颈椎有限元模型的应用进展%Application progress of finite element model in cervical spine

    Institute of Scientific and Technical Information of China (English)

    周毅强; 张建新; 林蔚莘

    2014-01-01

    有限元分析法(FEA)是一种在生物力学领域广泛应用的研究方法.近年来,颈椎有限元模型已被广泛应用于研究颈椎损伤、颈椎退变及模拟各种颈椎手术,已日趋完善.回顾了颈椎有限元模型的发展,介绍了颈椎有限元建模与分析在颈椎损伤、人工椎间盘置换、椎间植骨融合、颈椎退变及颈椎失稳等方面的应用进展,展望了未来的发展趋势.%Finite element analysis (FEA) is broadly used in biomechanics.Being widely used in clinical studies on cervical spine injury,cervical degeneration and stimulating a variety of cervical spine surgeries,cervical finite element model is becoming more and more accurate in recent years.This paper aims to review the development of cervical finite element model,to introduce the application progress of the modeling and analysis in cervical spine injury,cervical disc arthroplasty,cervical interbody fusion,cervical degeneration and cervical instability,and to prospect the foreground of cervical finite element model in future.

  2. Anterior Cervical Fusion with Cervical Hollow Threaded Fixator for Cervical Spondylotic Myelopathy%脊髓型颈椎病前路减压椎间融合器临床应用

    Institute of Scientific and Technical Information of China (English)

    刘利乐; 曹盛俊; 王文军; 陈志伟

    2001-01-01

    Objectives: To evaluate the effect of anterior cervica l fusion with cervical hol low threaded fixator (CHTF,Synthys) for cervical spondylotc myelopathy as substi tute for the conventional anterior fusion. Methods: 18 patients with cervi cal spondylofie myelopathy were treated with the new method and followed up afte r surgery.Results:6 months to 1 year postoperatively, the clinical symptom s were obviously improved, the stability of cervical segmental unit was satisfact ory and the normal lordosis was obtained. There were no stenosis of the cervical canal and no displacement of the cervical body. The average time for the cervic al fusion was 4.5 months.%目的 探讨脊髓型颈椎病(CSM)前路减压,颈椎空心螺纹内固定器(CHTF)椎间融合,代替 传统的前路减压,植骨融合的方法。方法 对18例CMS采用环锯减压再潜行扩大减压,植入C HTF无磁性医用钛合金空心螺纹内固定器椎间融合,随访疗效,进行分析。结果 植入CHTF 术后随访6个月至1年,症状改善明显,稳定性好,生理曲度恢复达正常,无椎间隙高度丢 失,无CHTF滑脱、移位。术后平均4.5个月椎间隙融合。

  3. 纳米羟基磷灰石/聚酰胺66复合生物活性椎间融合器的临床应用%Clinical application of a bioactive nano-hydroxyapatite/polyamide 66 interbody fusion cage

    Institute of Scientific and Technical Information of China (English)

    王茂源; 谢瑞莲; 何春耒; 刘午阳; 黄为民; 高辉

    2013-01-01

      背景:目前常用的椎间融合方法较多,有自体骨块、同种异体骨及钛合金为主的腰椎后路椎间融合器等方法,但各有其优缺点。  目的:观察纳米羟基磷灰石/聚酰胺66复合生物活性椎间融合器用于腰椎后路椎间融合治疗腰椎疾患的临床疗效。  方法:回顾性分析2010年7月至2011年12月赣南医学院第一附属医院骨科收治的行腰椎后路椎间融合患者16例,均置入纳米羟基磷灰石/聚酰胺66复合生物活性椎间融合器。  结果与结论:所有患者随访10-24个月,腰痛均明显减轻,末次随访时腰痛疼痛目测类比评分、腰椎JOA评分及Oswestry功能障碍指数均较治疗前明显改善(P al ograft bone and titanium-based posterior lumbar interbody fusion, and each method has its own advantages and disadvantages. OBJECTIVE:To observe the clinical efficacy of a bioactive nano-hydroxyapatite/polyamide 66 fusion cage in posterior lumbar interbody fusion for the treatment of lumbar disease. METHODS:A retrospective case analysis was conducted on 16 cases treated with posterior lumbar interbody fusion at the Department of Orthopedic, the First Affiliated Hospital of Gannan Medical University from July 2010 to December 2011, and al the patients were implanted with nano-hydroxyapatite/polyamide 66 biological activity fusion cage. RESULTS AND CONCLUSION:Al the patients were fol owed-up for 10-24 months, and the lumbar pain was significant improved, the lumbar visual analogue score, lumbar Japanese Orthopaedic Association score and Oswestry disability index score were significantly improved during the final fol ow-up period (P fusion without nano-hydroxyapatite/polyamide 66 fusion cage displacement or subsidence. The results indicate that nano-hydroxyapatite/polyamide 66 fusion cage for the treatment of posterior lumbar interbody fusion can reconstruct the lumbar stability and provide immediate stability after

  4. Lumbar interbody fusion with porous biphasic calcium phosphate enhanced by recombinant bone morphogenetic protein-2/silk fibroin sustained-released microsphere: an experimental study on sheep model.

    Science.gov (United States)

    Chen, Liang; Liu, Hai-Long; Gu, Yong; Feng, Yu; Yang, Hui-Lin

    2015-03-01

    Biphasic calcium phosphate (BCP) has been investigated extensively as a bone substitute nowadays. However, the bone formation capacity of BCP is limited owing to lack of osteoinduction. Silk fibroin (SF) has a structure similar to type I collagen, and could be developed to a microsphere for the sustained-release of rhBMP-2. In our previous report, bioactivity of BCP could be enhanced by rhBMP-2/SF microsphere (containing 0.5 µg rhBMP-2) in vitro. However, the bone regeneration performance of the composite in vivo was not investigated. Thus, the purpose of this study was to evaluate the efficacy of BCP/rhBMP-2/SF in a sheep lumbar fusion model. A BCP and rhBMP-2/SF microsphere was developed, and then was integrated into a BCP/rhBMP-2/SF composite. BCP, BCP/rhBMP-2 and BCP/rhBMP-2/SF were implanted randomly into the disc spaces of 30 sheep at the levels of L1/2, L3/4 and L5/6. After sacrificed, the fusion segments were evaluated by manual palpation, CT scan, biomechanical testing and histology at 3 and 6 months, respectively. The composite demonstrated a burst-release of rhBMP-2 (39.1 ± 2.8 %) on the initial 4 days and a sustained-release (accumulative 81.3 ± 4.9 %) for more than 28 days. The fusion rates, semi-quantitative CT scores, fusion stiffness in bending in all directions and histologic scores of BCP/rhBMP-2/SF were significantly greater than BCP and BCP/rhBMP-2 at each time point, respectively (P sheep using BCP constructs.

  5. Transforaminal lumbar interbody fusion combined with unilateral pedicle screw fixation for upper lumbar disc hernia-tion%经椎间孔行腰椎间融合联合单侧椎弓根螺钉固定术治疗高位腰椎间盘突出症疗效分析

    Institute of Scientific and Technical Information of China (English)

    谭健; 李平元; 欧军; 苏小桃; 卢政好

    2014-01-01

    Objective To investigate the clinical effect of transforaminal lumbar interbody fusion (TLIF) combined with unilateral pedicle screw fixation for upper lumbar disc herniation. Methods Retrospectively analysed the clinical data of 16 patients with upper lumbar disc herniation from Jun 2009 to Feb 2013 in our hospital, who were treated with transforaminal lumbar interbody fusion combined with unilateral pedicle screw fixation;using the visual analogue scale assessed the pain degree of patients at admission and after operation; assessed the clinical efficacy at last follow-up according to the modified MacNab criteria and observed intervertebral fusion. Results 16 patients were followed up 12 to 52 months (average 24.2 months) after surgery. All the patients had no nerve damage and leakage of cerebrospinal fluid complications. VAS score at different postopera-tive periods had significant difference compared with the VAS score before operation (P<0.01). According to the modified Mac-Nab criteria,the excellent and good rate was 93.75%. X-ray examination showed that there were no internal fixation failure and lumbar interbody non-fusion at the last follow-up. Conclusion Transforaminal lumbar interbody fusion combined with uni-lateral pedicle screw fixation has satisfied effect in the treatment of upper lumbar disc herniation,and has the advantages of small trauma,less complications,low cost.%目的:探讨经椎间孔行腰椎间融合(transforaminal lumbar interbody fusion,TLIF)联合单侧椎弓根螺钉固定术治疗高位腰椎间盘突出症的临床疗效。方法回顾性分析2009年6月~2013年2月本院16例高位腰椎间盘突出症患者临床资料,均采用TLIF联合单侧椎弓根螺钉固定术治疗;采用腰腿痛视觉模拟评分测评入院时和TLIF联合单侧椎弓根螺钉固定术后(术后1周、1个月、3个月及末次随访)患者疼痛情况,末次随访采用改良MacNab标准评定临床疗效,并了解椎间融合

  6. Dynesys动态稳定系统置入内固定与后路腰椎间融合修复腰椎退行性病的比较%Dynesys dynamic stabilization system versus posterior lumbar interbody fusion in treatment of lumbar degenerative disease

    Institute of Scientific and Technical Information of China (English)

    彭超; 何智勇; 母建松; 兰海; 李开南

    2014-01-01

    背景:后路腰椎椎体间融合是腰椎退行性疾病经典的治疗方法,目前大量研究表明,融合固定后的相邻节段会发生退变。近年来越来越多的学者关注脊柱的非融合固定技术发展。  目的:比较Dynesys动态稳定系统置入内固定和后路腰椎椎体间融合治疗腰椎退行性疾病的临床疗效。  方法:对2009年7月至2010年7月收治的56例退行性腰椎间盘疾病患者的临床资料进行回顾性对比分析,其中采用Dynesys动态稳定系统置入内固定治疗28例,采用后路腰椎椎体间融合治疗28例。比较两组患者的手术时间、出血量、治疗后住院时间,应用目测类比评分进行疼痛评估,以Oswestry功能评分评价临床疗效。  结果与结论:56例患者均获随访,随访时间18-24个月。两组患者治疗后12个月随访时的Oswestry功能评分、目测类比评分均较治疗前有明显改善(P OBJECTIVE:To compare clinical effects of Dynesys dynamic stabilization system fixation and posterior lumbar interbody fusion in treatment of lumbar degenerative disease. METHODS:From July 2009 to July 2011, clinical data of 56 patients with lumbar degenerative disease were retrospectively analyzed. There were 28 cases of Dynesys dynamic stabilization system fixation, and 28 cases of posterior lumbar interbody fusion. Operation time, bleeding volume, and postoperative hospitalization time were compared in both groups. Visual analog scale was used to assess pain. Oswestry disability index was utilized to evaluate clinical effects. RESULTS AND CONCLUSION:A total of 56 patients were fol owed up for 18-24 months. Visual analog scale and Oswestry disability index scores were significantly improved at 12 months after treatment in both groups (P<0.01). Significant differences in operation time, bleeding volume, and postoperative hospitalization time were detected between both groups (P<0.01). Dynesys dynamic

  7. Dynamic stabilization using the Dynesys system versus posterior lumbar interbody fusion for the treatment of degenerative lumbar spinal disease: a clinical and radiological outcomes-based meta-analysis.

    Science.gov (United States)

    Lee, Chang-Hyun; Jahng, Tae-Ahn; Hyun, Seung-Jae; Kim, Chi Heon; Park, Sung-Bae; Kim, Ki-Jeong; Chung, Chun Kee; Kim, Hyun-Jib; Lee, Soo-Eon

    2016-01-01

    OBJECTIVE The Dynesys, a pedicle-based dynamic stabilization (PDS) system, was introduced to overcome the drawbacks of fusion procedures. Nevertheless, the theoretical advantages of PDS over fusion have not been clearly confirmed. The aim of this study was to compare clinical and radiological outcomes of patients who underwent PDS using the Dynesys system with those who underwent posterior lumbar interbody fusion (PLIF). METHODS The authors searched PubMed, Embase, Web of Science, and the Cochrane Database. Studies that reported outcomes of patients who underwent PDS or PLIF for the treatment of degenerative lumbar spinal disease were included. The primary efficacy end points were perioperative outcomes. The secondary efficacy end points were changes in the Oswestry Disability Index (ODI) and back and leg pain visual analog scale (VAS) scores and in range of motion (ROM) at the treated and adjacent segments. A meta-analysis was performed to calculate weighted mean differences (WMDs), 95% confidence intervals, Q statistics, and I(2) values. Forest plots were constructed for each analysis group. RESULTS Of the 274 retrieved articles, 7 (which involved 506 participants [Dynesys, 250; PLIF, 256]) met the inclusion criteria. The Dynesys group showed a competitive advantage in mean surgery duration (20.73 minutes, 95% CI 8.76-32.70 minutes), blood loss (81.87 ml, 95% CI 45.11-118.63 ml), and length of hospital stay (1.32 days, 95% CI 0.23-2.41 days). Both the Dynesys and PLIF groups experienced improved ODI and VAS scores after 2 years of follow-up. Regarding the ODI and VAS scores, no statistically significant difference was noted according to surgical procedure (ODI: WMD 0.12, 95% CI -3.48 to 3.72; back pain VAS score: WMD -0.15; 95% CI -0.56 to 0.26; leg pain VAS score: WMD -0.07; 95% CI -0.47 to 0.32). The mean ROM at the adjacent segment increased in both groups, and there was no substantial difference between them (WMD 1.13; 95% CI -0.33 to 2.59). Although the

  8. Preliminary documentation of the comparable efficacy of vitoss versus NanOss bioactive as bone graft expanders for posterior cervical fusion

    OpenAIRE

    Nancy E Epstein

    2015-01-01

    Background: Laminectomies with posterior cervical instrumented fusions often utilize bone graft expanders to supplement cervical lamina/iliac crest autograft/bone marrow aspirate (BMA). Here we compared posterior fusion rates utilizing two graft expanders; Vitoss (Orthovita, Malvern, PA, USA) vs. NanOss Bioactive (Regeneration Technologies Corporation [RTI: Alachua, FL, USA]). Methods: Two successive prospective cohorts of patients underwent 1-3 level laminectomies with 5-9 level posterio...

  9. Treatment of the upper cervical instability 18 cases with occipital-cervical fusion surgery%枕颈融合术治疗上颈椎不稳18例

    Institute of Scientific and Technical Information of China (English)

    宋楹卓; 杜俊杰; 罗卓荆; 梁伟; 张建

    2012-01-01

    Objective To study the effect of occipital-cervical fusion in the treatment of upper cervical instability. Methods 18 cases of patients with upper cervical instability in our department were used occipital-cervical fusion surgery, and spinal cord function was assessed by the JOA score. Results 18 cases were followed up 3 months to 2 years after surgery, all the patients showed complete fusion, the upper cervical were stability, JOA score improved rate was 67.0%. Conclusion The occipital-cervical fusion surgery is effective to treat the upper cervical instability and spinal cord compression.%目的 研究枕颈融合手术治疗上颈椎不稳的疗效.方法 对我科上颈椎不稳患者18例行枕颈融合内固定手术,按JOA评分进行脊髓功能评定.结果 术后3个月~2年随访,全部病例上颈椎稳定性良好,植骨全部愈合,JOA评分平均改善率为67.0%.结论 枕颈融合术治疗上颈椎不稳、脊髓受压有确切治疗效果.

  10. Coflex与传统手术方法治疗腰椎退行性疾病疗效的Meta分析%Coflex versus posterior lumbar interbody fusion in the treatment of lumbar spine degenerative diseases: a Meta analysis

    Institute of Scientific and Technical Information of China (English)

    赵海恩; 郭明君; 梅玉峰; 于洋; 王育才; 马保安; 姬振伟; 范清宇

    2012-01-01

    [Objective] To analyze the efficacy and safety of Coflex versus posterior lumbar interbody fusion in the treatment of lumbar spine degenerative diseases such as LSS. [ Methods ] A systematic computer - based search of Medline, EM-BASE, Cochrance Central, and manual search of related journals were performed for collecting controlled trials. RevMan 5. 1 software was used for meta analysis. [Results] Twelve studies involving a total of 684 patients were included. The meta - analysis indicated that statistically significance were noted between two procedures for the operation time, length of hospital stay, blood loss and range of motion of lumbar. While no differences were noted for the low back VAS, ODI and JO A. [Conclusion] Both procedures were effective and safe in pain relief and functional recovery for lumbar spine degenerative diseases. Coflex could also shorten the operation time and length of hospital stay, decrease the blood loss. It showed that Coflex had biomechanical superiority in a short follow - up period.%[目的]系统评价Coflex与传统融合固定两种手术方法治疗腰椎退行性病变的有效性和安全性.[方法]计算机检索数据库,手工检索骨科相关杂志,纳入关于Coflex与传统治疗腰椎退行性病变的研究并进行Meta分析.[结果]纳入12篇研究共684病例,Meta分析结果显示:Coflex与传统手术方法相比较,前者在手术时间和住院时间上短于后者,失血量少于后者,手术节段的ROM大于后者,差异具有统计学意义.后背VAS和JOA差异无统计学意义.[结论]在达到相同治疗效果的情况下,Coflex可以明显减少手术时间、术中出血量和住院时间,而且可以保持手术节段腰椎存在一定活动度,避免了邻近节段的退变,术后短期内随访显示了其生物力学上优越性.

  11. 微创经椎间孔腰椎椎间融合术治疗老年腰椎退变性疾病%Minimally invasive transforaminal lumbar interbody fusion for lumbar degenerative diseases in elder-ly

    Institute of Scientific and Technical Information of China (English)

    陈云生; 陈荣春; 郭朝阳; 游辉; 钟红发; 张树芳

    2013-01-01

    Objectives: To evaluate outcomes of posterior transforaminal lumbar interbody fusion (MI-TLIF) under Pipeline expandable access system for lumbar degenerative diseases in elderly. Methods: From Febru-ary 2010 to June 2012, 46 elderly patients with lumbar degenerative diseases who underwent TLIF by using two different approaches were retrospectively analyzed. All patients were classified into observation group(MI-TLIF group) and control group(conventional open TLIF, CO-TLIF) according to the operative methods. There were 24 cases in observation group including 15 males and 9 females, aged from 60 to 79 years (average, 66.3 years), and the course of diseases ranging from 6 to 60 months(average, 18.5 months); 22 cases in con-trol group including 10 males and 12 females, aged from 62 to 75 years(average, 67.0 years), and course of diseases ranging from 8 to 64 months(average, 22.6 months). The blood loss, operation time, amount of blood transfusion and postoperative complications were compared. The clinical outcomes of both groups were evalu-ated by using the VAS(at postoperative 1 week, 3 months and the final follow-up) and ODI(at postoperative 3 months and the final follow-up), respectively. The bony fusion of both groups were assessed by the Suk stan-dard at the final follow-up. Results: There were significant differences on blood loss, amount of blood trans-fusion and postoperative complications (P0.05). All patients were followed up for an average of 18 months(range, 13 to 26 months). The VAS and ODI of both groups at each time point postoperatively experienced improvement compared with the preoperation (P0.05). Conclusions: MI-TLIF has similar surgical outcome with CO-TLIF for lumbar degenerative diseases in elderly, but the former has less blood loss and complications than the latter.%目的:探讨Pipeline可扩张通道辅助下行后路经椎间孔腰椎椎间融合术(minimally invasive transforam-inal lumbar interbody fusion,MI-TLIF)治疗老年腰

  12. Leakage of cerebrospinal fluid and secondary intracranial infection induced by Cloward technique of cervical discectomy and fusion: presentation and treatment

    Institute of Scientific and Technical Information of China (English)

    GUO Hong-bin; YANG Shu-xu; WANG Yi-rong

    2008-01-01

    @@ Cloward technique of cervical discectomy and fusion is a long and complex surgical proce dure and instrumentation, by which compli-cated infection is rare in an era of routine prophylactic antimicrobial agent, especially in procedures by anterior approach. A study in the journal of Spine suggested that the incidence of unintentional laceration of the dura mater during spinal surgery might be as high as 14%.

  13. 微创经椎间孔腰椎间融合术治疗腰椎退变性疾病%Clinical outcome of minimally invasive transforaminal lumbar interbody fusion in the treat-ment of lumbar degenerative disease

    Institute of Scientific and Technical Information of China (English)

    高爱国; 赵鹏; 张钦; 程力

    2016-01-01

    目的:探讨微创经椎间孔腰椎间融合术( MIS-TLIF)治疗腰椎退变性疾病的可行性和早期疗效。方法采用MIS-TLIF治疗30例腰椎退变性疾病患者,其中Ⅰ~Ⅱ度退行性或峡部裂型腰椎滑脱症12例,退行性腰椎管狭窄伴节段性不稳8例,腰椎间盘突出症10例。均为单节段融合。结果手术时间127~209(168±41) min;术中出血量23~361(192±169) ml;术中X线照射时间72~136(104±32) s;术后首次下床活动时间1.4~3.8(2.6±1.2) d。疼痛VAS评分术前(7.20±1.02)分,末次随访(1.71±0.66)分,差异有统计学意义(P<0.01)。末次随访椎间融合率为100%。未发生并发症。 X线片显示cage无移位、松动、下沉,椎弓根钉无松动、折断。结论 MIS-TLIF对腰椎的解剖结构破坏小,对椎旁肌肉的剥离少,患者术后恢复快,是一种有效、安全、损伤较小的手术方法,可用于腰椎不稳、局限节段椎间盘病变、≤Ⅱ度以下腰椎滑脱的患者;但手术时间较长,医患X线暴露较多。%Objective To investigate the feasibility and early curative effect of minimally invasive transforaminal lum-bar interbody fusion ( MIS-TLIF) in the treatment of low lumbar degenerative disease. Methods A total of 30 pa-tients underwent MIS-TLIF for low lumbar degenerative disease. They contained 12 cases ofⅠ~Ⅱdegree spondylo-listhesis,8 cases of degenerative lumbar spinal stenosis with segmental instability and 10 cases of protrusion of lumbar intervertebral disc. All the patients underwent one-level fusion by the same surgeon. Results The surgical time, in-traoperative blood loss volume, X-ray exposed time and the first leaving bed time after surgery were 127~209(168 ± 41) min, 23~361(192 ± 169) ml, 72~136(104 ± 32) s,1. 4~3. 8(2. 6 ± 1. 2) d. VAS of the preoperative and the last follow-up were (7. 20 ± 1. 02)points and (1. 71 ± 0. 66)points,the difference had statistical significance(P<0. 01

  14. Complications and clinical outcomes of minimally invasive transforaminal lumbar interbody fusion for the treatment of one- or two-level degenerative disc diseases of the lumbar spine in patients older than 65 years

    Institute of Scientific and Technical Information of China (English)

    WU Wen-jian; LIANG Yu; ZHANG Xin-kai; CAO Peng; ZHENG Tao

    2012-01-01

    Background Minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) has been successfully used to treat degenerative diseases of the lumbar spine.There are few reports comparing the complications and clinical outcomes in older patients who have undergone one- or two-level MIS-TLIF with those of younger patients.The aim of this study was to investigate the clinical outcomes of MIS-TLIF in the treatment of degenerative disc disease of lumbar spine of the patients older than 65 years,with an emphasis on perioperative complications compared to the younger patients.Methods One hundred and fifty-one consecutive cases of one- or two-level degenerative disc disease of lumbar spine treated with MIS-TLIF were reviewed for the radiological and clinical outcomes.They were divided into elderly group (age ≥65 years old) and younger group (age <65 years old),and were followed for at least 6 months.Radiographs were obtained before and after surgery,3 months postoperatively,and at the final follow-up to determine the presence of fusion,hardware-related problems.The clinical outcomes were evaluated using the Oswestry Disability Index (ODI)before and after surgery,and at the final follow-up.The visual analogue scale (VAS) score of back and leg pain were evaluated as well.The intra-operative data and peri-operative complications were recorded.Results The mean age of these patients at operation was (57.7±14.2) years (range 26-82 years).Of 151 patients,62were 65 years or older.The elderly patients had more comorbidities and more porportion of lumbar canal stenosis.The overall fusion rate was 88.4% at the final follow-up,with no significant difference between younger and elderly patients.The ODI,the VAS of back pain and radicular pain of both young and elderly group were significantly improved aftersurgery and at the final follow-up,without significant difference between two groups.There were 16 complications with an incidence of 10.6%,including 7 major complications

  15. Unilateral instrumented transforaminal lumbar interbody fusion in low lumbar degenerative diseases%单侧椎弓根固定经椎间孔椎体间融合术治疗下腰椎退行性疾病

    Institute of Scientific and Technical Information of China (English)

    贾其余; 俞宇; 王林; 郭万根; 胡联英; 程晓东

    2014-01-01

    目的:评价单侧椎弓根固定经椎间孔腰椎椎体间融合术( TLIF)治疗下腰椎退行性疾病的疗效。方法采用单侧TLIF术治疗41例下腰椎退行性疾病患者,均为单节段手术。观察手术时间、术中出血量及并发症情况。采用腰痛和腿痛视觉模拟评分( VAS)与Oswestry功能障碍指数( ODI)评价临床效果,并通过影像学检查对椎体间融合情况进行评价。结果41例均获随访,时间24~59(38±6)个月。手术时间80~180(125±10)min,术中出血量100~550(310±30)ml。手术切口均一期愈合。腰痛VAS分值由术前的(6.5±2.1)分下降至末次随访时的(2.3±0.9)分(P<0.01),腿痛VAS分值由术前的(7.6±2.3)分下降至末次随访时的(1.2±0.8)分(P<0.01),ODI由术前的54.2±10.9下降至末次随访时的13.8±2.1(P<0.01)。末次随访融合率为95%,未发现继发性脊柱侧弯、螺钉松动、断裂及Cage移位等情况。结论单侧TLIF术可有选择地治疗下腰椎退行性疾病,其疗效确切,并具有创伤小、手术时间短、出血少、并发症少等优点。%Objective To investigate the effect of unilateral instrumented transforaminal lumbar interbody fusion ( TLIF) in the treatment of low lumbar degenerative diseases. Methods 41 patients with low lumbar degenerative diseases in single segment were treated with unilateral pedicle screw fixation TLIF. Operative time, intraoperative blood loss and complications were observed. The visual analogue scale ( VAS ) and the Oswestry disability index ( ODI) were used to evaluate clinical effect, and radiographic parameters were used to evaluate the fusion rates. Re-sults All cases were followed up for 24~59(38 ±6)months. The operative time was 80~180(125 ±10)min, the intraoperative blood loss was 100~550(310 ± 30) ml. All incisions healed by first intention. The lumbar pain VAS scores dropped from 6. 5 ± 2. 1 preoperatively to 2. 3 ± 0. 9 at final followed-up (P <0. 01), the limb pain VAS

  16. 椎间撑开解剖复位对于退变性腰椎滑脱症价值的前瞻性比较研究%Prospective comparison research of intervertebral disc space distraction and anatomical reduction of instrumented posterior lumbar interbody fusion for lumbar degenerative spondylolisthesis

    Institute of Scientific and Technical Information of China (English)

    刘好源; 黄哲元; 陈峰嵘; 黄建明; 简国坚; 龚灏; 徐天睿; 王博文; 王俊; 叶志扬

    2015-01-01

    目的:通过前瞻性研究评价椎间撑开解剖复位对于退变性腰椎滑脱症价值.方法:2006年1月~2009年12月,对56例退变性腰椎滑脱症(II度以上)患者均施行经后路椎体间融合术(posteriorlumbarinterbodyfusion,PLIF),但随机选择是否在术中进行解剖复位的操作,复位组30例,对照组26例,随访时比较两组病例的影像学、JOA功能障碍评分及并发症.结果:56例均获得13~46个月(平均32月)随访.复位组的影像学结果及最终融合率均优于对照组(P<0.01).末次随访时,两组患者都有较高的JOA功能障碍评分,复位组略优于对照组(P<0.01).复位组和对照组的并发症发生率分别为10%和23.1%.结论:经后路椎体间融合术治疗退变性腰椎滑脱症术中进行解剖复位可以获得更为理想的影像学结果、植骨融合及生活质量.%Objective:To prospectively evaluate the special roles of anatomical reduction of instrumented posterior lumbar interbody fusion for lumbar degenerative spondylolisthesis.Methods:From January 2006 to December 2009, fifty-six lumbar degenerative spondylolisthesis cases were treated by instrumented posterior lumbar interbody fusion, all surgical cases were randomly divided into reduction group and matched group according to whether anatomical reduction. The definitive reduction of the spondylolisthesis using pedicle screw instrumentation was followed by primary reduction using intervertebral disc space distraction and interbody fusion with insert cages and local morselized bone after decompressive laminectomy. Main outcome measurements included imaging, JOA dysfunction score and complication.Results:Fifty-six patients were followed up for 13 to 46 (average, 32) months, the Imaging results and solid bony fusion rate of reduction group were better than matched group (P<0.01). Both groups had preferable JOA dysfunction score. Reduction group was slightly better than matched group (P<0.01). The complication rates for

  17. Effects of retractor application on cuff pressure and vocal cord function in patients undergoing anterior cervical discectomy and fusion

    Directory of Open Access Journals (Sweden)

    Rakesh Garg

    2010-01-01

    Full Text Available Anterior cervical discectomy and fusion is a commonly performed procedure for prolapse of cervical intervertebral disc. It involves retraction of soft tissue of neck for adequate exposure of anterior spinal canal. Increased cuff pressure with retractor application may affect the postoperative vocal cord function. Cuff pressures of tracheal tube were measured continuously in 37 patients using air-filled pressure transducer connected to the pilot balloon. Changes of pressure from baseline values were noted after application of cervical retractor. At the end of procedure, vocal cord movement was observed using fibreoptic bronchoscope. Significant increase in cuff pressure (168% of baseline values and airway pressure of tracheal tube during cervical retraction was observed. The vocal cord function was assessed using fibreoptic laryngoscope. One patient developed right vocal cord palsy (2.7% and two patients had postoperative hoarseness of voice (5.4%. All these complications improved over a period of time. It is suggested that the cuff of tracheal tube should be inflated to achieve ′just seal′, with adequate cuff pressure monitoring. Intermittent release of cervical retraction may help to prevent laryngeal morbidities.

  18. Effects of retractor application on cuff pressure and vocal cord function in patients undergoing anterior cervical discectomy and fusion.

    Science.gov (United States)

    Garg, Rakesh; Rath, Girija P; Bithal, Parmod K; Prabhakar, Hemanshu; Marda, Manish K

    2010-07-01

    Anterior cervical discectomy and fusion is a commonly performed procedure for prolapse of cervical intervertebral disc. It involves retraction of soft tissue of neck for adequate exposure of anterior spinal canal. Increased cuff pressure with retractor application may affect the postoperative vocal cord function. Cuff pressures of tracheal tube were measured continuously in 37 patients using air-filled pressure transducer connected to the pilot balloon. Changes of pressure from baseline values were noted after application of cervical retractor. At the end of procedure, vocal cord movement was observed using fibreoptic bronchoscope. Significant increase in cuff pressure (168% of baseline values) and airway pressure of tracheal tube during cervical retraction was observed. The vocal cord function was assessed using fibreoptic laryngoscope. One patient developed right vocal cord palsy (2.7%) and two patients had postoperative hoarseness of voice (5.4%). All these complications improved over a period of time. It is suggested that the cuff of tracheal tube should be inflated to achieve 'just seal', with adequate cuff pressure monitoring. Intermittent release of cervical retraction may help to prevent laryngeal morbidities.

  19. Extreme lateral transforaminal lumbar interbody fusion (E-TLIF) designed via digital technology%数字化设计微创极外侧经椎间孔腰椎椎体间融合术

    Institute of Scientific and Technical Information of China (English)

    杨明杰; 李立钧; 祝建光; 潘杰; 谭军

    2011-01-01

    目的 通过数字技术设计一种新的手术方式——微创极外侧经椎间孔腰椎椎体间融合术(extreme lateral transforaminal lumbar interbody fusion,E-TLIF),并探讨其治疗退变性腰椎疾患的可行性.方法 通过对志愿者(男,26岁,健康,体重67 kg,身高172 cm)腰椎行CT扫描及Mimics三维重建,研究椎间孔区域骨性结构和神经根走行,探讨腰椎椎间孔区域的解剖学特点.在Mimics软件中模拟E-TLIF手术操作,切除上关节突而保留下关节突,并植入椎弓根螺钉和椎体间融合器.最后通过尸体模拟手术证实E-TLIF的可行性.结果 正中线旁开9 cm的纵行手术切口,45°斜向椎体的手术通道可以充分暴露病椎的椎间孔区域.通过E-TLIF手术途径可充分地显露目标椎间盘和神经根以及后方的上、下关节突和关节囊,操作简便直观.E-TLIF手术可以实现单纯切除上关节突,而保留下关节突,通过扩大的椎间孔牵开神经根后可以显露并切除椎间盘,并能完成椎间融合器的植入.结论 (1)通过Mimics可以精确地进行手术设计,模拟手术操作.成本低,可操作性强,对真实手术有较好的指导作用.(2)E-TLIF手术仅切除上关节突而保留了下关节突,在达到与传统手术同样的减压、固定、融合效果的同时,更完整保留了脊柱后方的张力带结构,加强术后即刻稳定性,并促进患者更快恢复,是一种创伤更小、安全、有效的腰椎椎体间融合术式.%Objective To design a new operation approach:extreme lateral transforaminal lumbar interbody fusion (E-TLIF) via digital technology and to discuss its feasibility in treatment of degenerative lumbar diseases.Methods CT scan image data of lumbar vertebra were obtained from volunteer (a healthy male of 26 years old,67 kg in weight and 172 cm in height).Mimics was used to read and reconstruct the data into 3D images.We observe the anatomical bone structures of intervertebral foramen and nerve

  20. Correlation of posterior lumbar interbody fusion procedures with spinal and pelvic balance%后正中入路腰椎间融合与脊柱骨盆平衡相关性研究

    Institute of Scientific and Technical Information of China (English)

    汪勇刚; 徐林军; 胡伟; 许永涛

    2016-01-01

    Objective To investigate the effect of posterior lumbar interbody fusion (PLIF) procedures on the sagittal balance of spine and pelvis in treatment of lumbar degenerative diseases. Methods Forty cases of lumbar disc herniation, lumbar spondylolisthesis or lumbar spinal stenosis admitted to our department from February 2011 to June 2012 and treated with PLIF procedures were retrospectively analyzed. The parameters of spinal the pelvic balance (SS, PT, PI, and LL) were measured before and after surgery, one year and two years af⁃ter surgery, respectively. Meanwhile, JOA scores were recorded to assess the improvement of symptoms and signs of low back pain. All the data were analyzed by SPSS 17.0 software package for the significance test. The P value was set at 0.05. Results There was significant difference in LL, SS and PT before and after operation (P<0.05). The lumbar lordosis and sacral slope was increased respectively from 38.6° ± 5.2° , 28.2° ± 6.7° to 46.8°±7.3°, 33.4°±5.3°, and the pelvic incidence was decreased from 21.6°±7.8° to 18.2±9.4°, but there was no significant difference between different postoperative periods. As compared with the preoperation, the JOA scores in 35 patients at the final follow⁃up were increased from (12.5 ± 1.8) to (21.6 ± 3.2) (P<0.05). Conclu⁃sion PLIF procedure can relieve symptoms and improve quality of life of patients. PLIF procedure can effec⁃tively improve lumbar lordosis, and the recovery to lumbar normal lordosis has a positive effect on the mainte⁃nance of sagittal balance of spine and pelvis.%目的:探讨采用经后正中入路腰椎间融合(posterior lumber interbody fusion, PLIF)治疗腰椎退变性疾病时对脊柱骨盆矢状面平衡的影响。方法回顾性分析2011年2月至2012年6月我院通过PLIF治疗腰椎间盘突出症、腰椎滑脱、腰椎管狭窄症的患者40例,以常用的脊柱骨盆平衡参数中的骨盆入射角(pelvic incidence, PI

  1. Effect comparison of minimally invasive and open transforaminal lumbar interbody fusion in the treatment of degenerative lumbar disease%微创和开放经椎间孔腰椎椎间融合术治疗腰椎退变性疾病的效果比较

    Institute of Scientific and Technical Information of China (English)

    陈文明; 黄华伟; 黄勇全

    2014-01-01

    Objective To compare the clinical effect of minimally invasive and open transforaminal lumbar interbody fusion in the treatment of degenerative lumbar disease. Methods 32 patients with degenerative lumbar disease in our hospital were selected as research subjects and randomly allocated to the research group and the control group,and there were 16 patients in each group.The control group received conventional open surgery,and the research group re-ceived minimally invasive transforaminal lumbar interbody fusion.Treatment effect between the two groups were com-pared. Results The total effective rate in the research group (93.75%) was obviously higher than that in the control group (68.75%) (P<0.05). Conclusion Minimally invasive transforaminal lumbar interbody fusion treating degenerative lumbar disease helps not only improve total curative effects,but also reduce postoperative complications,which is worthy of clinical promotion.%目的:比较微创和开放经椎间孔腰椎椎间融合术治疗腰椎退变性疾病的临床效果。方法选取本院收治的32例腰椎退变性疾病患者为研究对象,随机分为研究组与对照组,各16例,对照组给予传统开放手术治疗,研究组给予微创经椎间孔腰椎椎间融合术治疗,比较两组的治疗效果。结果研究组的总有效率为93.75%,明显高于对照组的68.75%(P<0.05)。结论采用微创经椎间孔腰椎椎间融合术治疗腰椎退变性疾病不仅可以提高整体治疗效果,还可以减少术后并发症的出现,值得临床推广。

  2. Dynesys与后路椎间融合治疗腰椎管狭窄症的临床效果比较研究%Dynesys and posterior lumbar interbody fusion for lumbar spinal stenosis in the comparative study of clinical effect

    Institute of Scientific and Technical Information of China (English)

    高洪亮

    2015-01-01

    Objective: To investigate the Dynesys and posterior lumbar interbody fusion in the treatment of lumbar spinal stenosis in.Methods:a total of August 2012 to 2014 years 5 months in our hospital from lumbar spinal stenosis were 85 cases, and were randomly divided into group A (n = 42) and group B (n = 43). The A group was treated by posterior lumbar interbody fusion, and the B group was treated by pedicle Dynesys operation, and the treatment effect was compared between the two groups. Results: there was no significant difference in the length of the incision in the A group and the B group (P>0.05). ODI score and VAS score were significantly lower in A group and B group (P0.05) and the VAS score at the end of groups (ODI).Conclusion: in lumbar spinal canal stenosis treatment in, posterior lumbar interbody fusion surgery and transpedicular Dynesys surgical treatment effect is similar, but the latter has a shorter operation time, less trauma and bleeding quantity low characteristic, can effectively stabilize the spine, and is worthy to be popularized.%目的:探讨Dynesys与后路椎间融合在腰椎管狭窄症中的治疗效果.方法:选取2012年8月到2014年5月我院收治的腰椎管狭窄症者85例,并随机分为A组(n=42)和B组(n=43).A组都采用后路椎间融合手术,B组均采用经椎弓根Dynesys手术治疗,对比两组的治疗效果.结果:A组、B组切口长度相比,差异无统计学意义(P>0.05).A组、B组末次随访ODI评分、VAS评分显著比手术前降低(P0.05).结论:在腰椎管狭窄症治疗中,后路椎间融合手术和经椎弓根Dynesys手术治疗效果相近,但后者具有手术时间短、创伤小和出血量低等特点,可有效地稳定脊柱,值得推广.

  3. Preliminary documentation of the comparable efficacy of vitoss versus NanOss bioactive as bone graft expanders for posterior cervical fusion

    Directory of Open Access Journals (Sweden)

    Nancy E Epstein

    2015-01-01

    Conclusion: In this preliminary study combining cervical laminectomy/fusions, the time to fusion (5.65 vs. 5.35 months, pseudarthrosis (2.7% vs. 0%, and infection rates (2.7% vs. 0% were nearly comparable sequentially utilizing Vitoss (72 patients vs. NanOss (20 patients as bone graft expanders.

  4. Mid- to Long-Term Outcomes of Cervical Disc Arthroplasty versus Anterior Cervical Discectomy and Fusion for Treatment of Symptomatic Cervical Disc Disease: A Systematic Review and Meta-Analysis of Eight Prospective Randomized Controlled Trials.

    Directory of Open Access Journals (Sweden)

    Yan Hu

    Full Text Available This study aimed to investigate the mid- to long-term outcomes of cervical disc arthroplasty (CDA versus anterior cervical discectomy and fusion (ACDF for the treatment of 1-level or 2-level symptomatic cervical disc disease.Medline, Embase, and the Cochrane Central Register of Controlled Trials databases were searched to identify relevant randomized controlled trials that reported mid- to long-term outcomes (at least 48 months of CDA versus ACDF. All data were analyzed by Review Manager 5.3 software. The relative risk (RR and 95% confidence intervals (CIs were calculated for dichotomous variables. The weighted mean difference (WMD and 95%CIs were calculated for continuous variables. A random effect model was used for heterogeneous data; otherwise, a fixed effect model was used.Eight prospective randomized controlled trials (RCTs were retrieved in this meta-analysis, including 1317 and 1051 patients in CDA and ACDF groups, respectively. Patients after an ACDF had a significantly lower rate of follow-up than that after CDA. Pooled analysis showed patients in CDA group achieved significantly higher rates of overall success, Neck Disability Index (NDI success, neurological success and significantly lower rates of implant/surgery-related serious adverse events and secondary procedure compared with that in ACDF group. The long-term functional outcomes (NDI, Visual Analog Scale (VAS neck and arm pain scores, the Short Form 36 Health Survey physical component score (SF-36 PCS, patient satisfaction and recommendation, and the incidence of superior adjacent segment degeneration also favored patients in CDA group with statistical difference. Regarding inferior adjacent segment degeneration, patients in CDA group had a lower rate without statistical significance.This meta-analysis showed that cervical disc arthroplasty was superior over anterior discectomy and fusion for the treatment of symptomatic cervical disc disease in terms of overall success, NDI

  5. 颈前路减压植骨治疗脊髓型颈椎病%Treatment of Anterior Cervical Decompression and Fusion with Cervical Spinal Cord

    Institute of Scientific and Technical Information of China (English)

    余润泽; 喻德富; 章杰斌; 陶学顺; 王家顺; 吕建军

    2011-01-01

    Objective To observe the cervical spinal column fusion anterior cervical decompression and clinical efficacy. Methods 21 cases of single or double in patients with cervical myclopathy were selected,Central Bank of antcrior cervical discectomy and decompression saws,implantation of autologous iliac bone fusion columnar neck immobilization were performed.The patients were followed up by cervical spine X-ray observations,fell,clinical functional evaluation of nerve function recovery.Results 21 patients were followed up for 12 to 24 months( mean 16 months ). Recovery after surgery,bone fusion,the basic life of patients were satisfactory, Some patients returned to work.Neurological function according to the Japanese Orthopacdic Association(JOA) evaluation system,excellent in 16 cases,good in 2 cases,in 2 cases,1 patient;JOA score improved from(9.3±2.1) points up to postoperative(15.4±1.6) points.Conclusion Anterior decompression and fusion was a single,double cervical myclopathy effective treatment,with complete decompression,shorter operation time,trauma,neurological recovery was good,and with low cost advantage.%目的 观察脊髓型颈稚病颈前路减压柱状植骨融合的临床疗效.方法 21例单或双节段脊髓型颈椎病患者,行颈前路环锯椎间盘切除减压,自体柱状髂骨植入融合,颈托外固定.术后随访观察颈椎X线片、自我感觉、临床功能评价、神经功能恢复情况.结果 21例患者全部获得随访,随访时间12~24个月(平均16个月).术后恢复满意,植骨全部融合,患者生活基本可自理,部分患者重返工作.神经功能改善依据日本矫形外科学会(JOA)评定标准,优16例,良2例,中2例,无效1例;JOA评分由术前(9.3±2.1)分上升至术后的(15.4±1.6)分.结论 前路减压植骨是单、双节段脊髓型颈椎病的有效治疗方法,具有减压彻底,手术时间短,创伤小,神经恢复好,费用低等优点;术后需较长期外固定.

  6. Comparison of 2 Zero-Profile Implants in the Treatment of Single-Level Cervical Spondylotic Myelopathy: A Preliminary Clinical Study of Cervical Disc Arthroplasty versus Fusion

    Science.gov (United States)

    Yang, Li-Li; Liu, Zu-De; Yuan, Wen

    2016-01-01

    Objectives Cervical disc arthroplasty (CDA) with Discover prosthesis or anterior cervical discectomy and fusion (ACDF) with Zero-P cage has been widely used in the treatment of cervical spondylotic myelopathy (CSM). However, little is known about the comparison of the 2 zero-profile implants in the treatment of single-level CSM. The aim was to compare the clinical outcomes and radiographic parameters of CDA with Discover prosthesis and ACDF with Zero-P cage for the treatment of single-level CSM. Methods A total of 128 consecutive patients who underwent 1-level CDA with Discover prosthesis or ACDF with Zero-P cage for single-level CSM between September 2009 and December 2012 were included in this study. Clinical outcomes were evaluated using the Japanese Orthopaedic Association (JOA) score and Neck Disability Index (NDI). For radiographic assessment, the overall sagittal alignment (OSA), functional spinal unit (FSU) angle, and range of motion (ROM) at the index and adjacent levels were measured before and after surgery. Additionally, the complications were also recorded. Results Both treatments significantly improved all clinical parameters (P 0.05). Besides, no significant differences existed in dysphagia, subsidence, or adjacent disc degeneration between the 2 groups (P > 0.05). However, significant differences occurred in prosthesis migration in CDA group. Conclusions The results of this study showed that clinical outcomes and radiographic parameters were satisfactory and comparable with the 2 techniques. However, more attention to prosthesis migration of artificial cervical disc should be paid in the postoperative early-term follow-up. PMID:27441736

  7. 潜行减压单侧改良TLIF手术治疗腰椎退行性疾患%Preliminary efficacy of decompressive unilateral improved transforaminal lumbar interbody fusion (TLIF) for the treatment of lumbar degenerative diseases

    Institute of Scientific and Technical Information of China (English)

    张居适; 胡松峰; 李志龙

    2014-01-01

    目的:观察椎管潜行减压单侧改良经椎间孔腰椎间融合术(transforaminal lumbar interbody fusion,TLIF)手术治疗腰椎退行性疾病的临床疗效。方法:自2009年8月至2011年12月,采用椎管潜行减压单侧改良TLIF手术治疗腰椎退行性疾病患者28例,其中男16例,女12例;年龄46~71岁,平均61岁;病程6个月~6年。腰椎管狭窄症20例,腰椎间盘突出症8例。潜行减压范围:单节段24例,双节段4例。左侧15例,右侧13例。采用JOA下腰痛评分系统(29分)评价手术前后临床症状、体征及括约肌功能;并采用视觉模拟评分(VAS)评估手术前后腰腿痛情况。结果:28例患者获随访,时间6~28个月,平均14个月。术后JOA、VAS评分(17.9±2.2、2.8±0.7)与术前(8.5±1.7、8.6±1.2)比较有明显改善(P<0.05)。28例患者椎间均达到骨性融合。结论:采用椎管潜行减压单侧改良TLIF手术治疗单侧根性症状的腰椎管狭窄症、腰椎间盘突出症,具有创伤小、疗效确切的优点;能明显节省医疗费用,值得临床研究推广。%Objective:To observe preliminary efficacy of decompressive unilateral improved transforaminal lumbar inter-body fusion(TLIF) for the treatment of lumbar degenerative diseases. Methods:From August 2009 to December 2011,28 pa-tients with lumbar degenerative diseases were treated by decompressive unilateral improved TLIF ,including 16 males and 12 females with an average of 61 (aged 46 to 71) years old,the courses of disease ranged from 6 months to 6 years. Among them , 20 cases suffered from lumbar spinal stenosis ,8 cases were lumbar disc herniation. Decompressive range included single seg-ment in 24 cases,and double segments in 4 cases;15 cases were performed operation on the left side,13 cases on the right side. JOA lower back pain scoring system (29 points) were applied for evaluate preoperative and postoperative

  8. Observation of Clinical Curative Effect of Transmultifidus Lumbar Interbody Fusion in the Treat-ment of Lumbar Degenerative Diseases%经多裂肌间隙椎间融合术治疗腰椎退行性疾病观察

    Institute of Scientific and Technical Information of China (English)

    赵建; 刘少; 林波; 刘丽平

    2014-01-01

    Objective To investigate and analyze the clinical curative effect of transmultifidus lumbar interbody fusion in the treatment of lumbar degenerative diseases. Methods 62 patients with lumbar degenerative diseases who came to our hos-pital from April,2011 to July,2012 were randomly divided into the control group and the experimental group according to the random number method. There were 31 cases in each group. The control group accepted transforaminal lumbar interbody fusion while the experimental group accepted transmultifidus lumbar interbody fusion. The clinical curative effect of the two groups was compared. Results Blood loss and postoperative drainage volume of the experimental group was significantly less than that of the control group(P0. 05). The VAS score in the 3rd day and 2 weeks after the operation,the ODI index in 1st month and 6th month of the experimental group was statistically better than that of the control group(P0. 05). Conclusion Transmultifidus lumbar interbody fusion has a significant effect in treating lumbar degenerative diseases. The approach has less damage during the operation and improves the efficacy of surgery and patients'quality of life. So it is worth promoting.%目的:探讨分析经多裂肌间隙入路椎体间融合治疗腰椎退行性疾病的临床疗效。方法选取我院自2011年4月至2012年7月收治的62例腰椎退行性疾病患者,将所有患者按随机数法分为实验组和对照组,各31例。对照组接受经椎间孔椎体间融合术,实验组接受经多裂肌间隙椎间融合术,对比分析两组患者的临床疗效。结果实验组术中出血量及术后引流量均明显少于对照组( P0.05),实验组术后3 d,术后2周的VAS评分及术后1个月与术后半年的ODI评分明显优于对照组( P0.05);实验组与对照组手术前及术后1年滑脱角、椎间隙高度及Taillard指数的比较差异无统计学意义( P>0.05)。结论经多裂肌间隙入路

  9. Lumbar interbody expanding cage. A preliminary study on an animal model.

    Science.gov (United States)

    Manunta, M L; Careddu, G M; Masala, G; Columbano, N; Doria, C; Crissantu, L; Sanna Passino, E

    2008-01-01

    Interbody fusion devices are used in human medicine for treating degenerative diseases of the spine. Currently, there is not a universally accepted assessment tool for determining fusion, and the definitive criteria for diagnosing a successful interbody fusion remain controversial. The aim of this study was to describe microscopic and helical computed tomography (CT) imaging in the assessment of lumbar interbody fusion using cylindrical threaded titanium expanding cage in sheep. One cylindrical threaded expanding titanium cage (Proconcept--SA, Orange, France) was inserted through a transperitoneal approach after radical discectomy and packed with cancellous bone autograft in five adult sheep. The subjects were euthanatized after three, six, 12, 18 and 24 months. CT images revealed lumbar fusion at 12 months post operation, whereas microscopic evaluations indicated the presence of lumbar fusion at 18 months. CT and histological grades were the same in 65% of the cases observed. There were not a significant difference between CT, histological and micro radiographic grades. Helical CT scanning can be considered to be a suitable method for the monitoring of lumbar fusion as it enables observation of the deposition of bony bridging within the cage. PMID:18704248

  10. 颈椎前路融合致邻近节段椎间盘退变的原因探讨%Causes of adjacent segments disc degeneration caused by anterior cervical fusion

    Institute of Scientific and Technical Information of China (English)

    张克非; 刘伟; 于长水; 袁绍辉; 潘琦

    2011-01-01

    目的 探讨颈椎前路融合后邻近节段椎间盘退变的原因及其防治办法.方法 对实施颈椎前路融合术的126例颈椎间盘突出症患者进行回顾性分析,归纳可能导致颈椎前路融合术后临近椎间盘退变突出的原因.结果 随访时间最短10个月,最长10年,平均7.8年.37例颈椎间盘突出症患者发生临近节段椎间盘退变加重,其中7例患者再次手术.结论 颈椎前路融合后邻近节段椎间盘退变的原因可能为临近节段原有退变加重,椎间融合后生物力学改变,临近节段应力集中.%To investigate the causes of the adjacent intervertebral disc degeneration after anterior decompression and interbody fusion of C-spine and search for the way of prevention.Methods A retrospective study was given to 126 patients who underwent an anterior decompression and interbody fusion of C-spine, the causes of the adjacent intervertebral disc degeneration after anterior decompression and interbody fusion of C-spine were analyzed. Results The follow-up time was from 10 months to 10 years, average 7.8 years. Thirty-seven patients occurred the aggravation of adjacent intervertebral discs degeneration, in which 7 patients underwent reoperation. Conclusion The possible causes of the adjacent intervertebral disc degeneration after anterior decompression and interbody fusion of C-spine is that the aggravation of original degeneration of adjacent intervertebral disc, the alteration of biomechanics after anterior decompression and interbody fusion of C-spine induces the stress concentration of the adjacent intervertebral disc.

  11. 三种单纯腰椎椎间融合并双侧椎弓根螺钉内固定后即刻稳定性的比较%Initial stability of lumbar spine following three types of interbody fusion and bilateral pedicle screw fixation

    Institute of Scientific and Technical Information of China (English)

    张烽; 陈兵乾; 居建文; 王素春; 段广超; 王以进

    2008-01-01

    BACKGROUND:Operative approaches of lumbar interbody fusion include anterior (ALIF),posterior (PLIF) and transforaminal lumbar interbody fusion (TLIF).The resected structures and cage implantation sites are different,and the initial stability of lumbar spine is varied.OBJECTIVE:To compare the initial stability of lumbar spine following ALIF,PLIF or TLIF in combination with bilateral pedicle screw fixation.DESIGN:Comparative observation.MATERIALS:Fifteen samples of fresh calf lumbar spine were used.METHODS:Models ofALIE PLIF and TLIF were simulated.After examination as normal group,the samples were randomly divided into three groups (n=5).Besides anterior,posterior and transforaminal lumbar interbody fusion include anterior,bilateral pedicle screw fixation was performed.MAIN OUTCOME MEASURES:Biomechanical characteristics of the lumbar spine before and after ALIF,PLIF or TLIF in combination with bilateral pedicle screw fixation.RESULTS:Following three approaches of lumbar interbody fusion,the stability of lumbar spine was significantly reduced,which was enhanced after bilateral pedicle screw fixation (torsion indexes were also increased).In addition,rigidity of the lumbar spine was enhanced.The stability indexes of lumbar spine following TLIF were significantly greater than the other approaches,indicating the initial stability of TLIF was the best.The rigidity,stress,and swain of lumbar spine following PLIF were greater than ALIE but torsion indexes were smaller than ALIE CONCLUSION:The stability of lumbar spine following lumbar interbody fusion was significantly reduced compared with normal sample.But bilateral pedicle screw fixation greatly increases the stability.Among three types of lumbar interbody fusion,the initial stability of lumbar spine following TLIF is the best.%背景:椎间融合术按照手术入路主要有前路椎间融合术、后路椎间融合术和椎间孔入路椎问融合术.3种融合术术中切除的结构不同,融合器置入的部位

  12. Clinical efficacy of modified posterior lumbar interbody fusion on degenerative lumbar dis-ease%改良后路椎间植骨融合术治疗腰椎退行性疾病

    Institute of Scientific and Technical Information of China (English)

    谭小云; 蒲涛; 刘计鲁; 赵丽; 刘伟; 许轩铭

    2015-01-01

    目的:探讨改良后路椎间植骨融合术(PLIF)治疗腰椎退行性疾病的临床效果。方法将186例腰椎退行性病变伴腰腿痛的患者分成两组,分别使用改良 PLIF 和传统 PLIF 治疗。记录所有患者术前、术后 VAS 评分和 JOA 评分。结果两组术后住院时间差异无统计学意义(P >0.05),而手术时间及术中出血量改良 PLIF组均优于传统 PLIF 组(P <0.05)。患者均获随访,时间6~36个月。JOA 评分:两组术后3个月和末次随访与术前比较差异均有统计学意义(P <0.05),术后3个月与末次随访比较差异均无统计学意义(P >0.05)。末次随访时两组 JOA 评分、VAS 评分比较差异均无统计学意义(P >0.05)。结论改良 PLIF 治疗腰椎退行性疾病可以获得与传统 PLIF 相同的临床效果,且具有手术时间短、术中出血少及组织损伤轻等优点。%Objective To explore the clinical outcomes of modified posterior lumbar interbody fusion (PLIF)in the treatment of degenerative lumbar disease.Methods 186 patients with degenerative lumbar disease were divided into 2 groups and treated with traditional PLIF and modified PLIF respectively.Visual analogue scale (VAS)scores and Japanese Orthopaedic Association (JOA)scores were recorded before and after the treatment.Results The postop-erative hospital stay was not different (P >0.05 ),but there were significant differences between the 2 groups in terms of operation time and blood loss (P 0.05).Neither was the JOA score (P >0.05).Conclusions Functional outcome of modified PLIF is similar to traditional PLIF technique in the treatment of degenerative lumbar disease.But it has shorter operation time,and less blood loss and tissue damage.

  13. 腰椎后路单Cage单侧椎体间融合术在腰椎退变性疾病中的应用%Posterior lumbar interbody fusion using a unilateral single cage in the degenerative lumbar spine

    Institute of Scientific and Technical Information of China (English)

    顾宇彤; 姚振均; 陈统一; 董健; 姜晓幸; 张键; 费琴明; 阎作勤

    2011-01-01

    目的 对单Cage单侧PLIF治疗腰椎退变性疾病的临床疗效及放射影像学结果进行回顾性分析.方法 2005年10月至2008年3月间,使用填有移植骨的单Cage单侧PLIF技术为55例腰椎退变性疾病患者施行手术,术中将腰椎后路减压所取下的骨块咬碎后填于Cage前方,术后平均随访39.2个月.使用VAS法对患者的术前、术后1年及末次随访进行临床评估,用ODI法对术前及末次随访的功能进行评估,在末次随访中使用Prolo评分法,放射影像学可通过椎间高度、Cage周围的骨桥、射线透亮区及过伸过屈侧位片上椎间不稳的表现来评估. 结果VAS评分、ODI指数、Prolo评分均表明该术式的临床疗效非常令人满意,放射影像学评估显示术后6月时55例中有96.4%(53例)获牢固融合,末次随访时所有病例均获得完全融合.结论 单Cage单侧PLIF治疗腰椎退变性疾病,能维持合适的椎间高度,有可靠的脊柱稳定性、良好的骨连接和较高的骨融合率,可获得令人满意的临床疗效和放射影像学结果.%Objective We retrospectively evaluated the clinical and radiological outcomes of posterior lumbar interbody fusion (PLIF) using a unilateral single cage and a local morselized bone graft. Methods Fifty five patients who underwent PLIF with a unilateral single cage filled with local morselized bone graft were enrolled in this study. The average follow-up duration was 39.2 months. The clinical outcomes were evaluated with the visual analogue scale (VAS) at the pre-operative period, at 1 year post-operation and at the final follow-up, the Oswestry Disability Index and the Prolo scale at the final follow-up; the radiological outcomes were evaluated according to the change of bone bridging, the radiolucency, the instability and the disc height.Results For the clinical evaluation, the VAS pain index, the Oswestry Disability Index and the Prolo scale showed excellent outcomes. For the radiological

  14. Postoperative dysphagia correlates with increased morbidity, mortality, and costs in anterior cervical fusion.

    Science.gov (United States)

    Joseph, Jacob R; Smith, Brandon W; Mummaneni, Praveen V; La Marca, Frank; Park, Paul

    2016-09-01

    Anterior cervical fusion (ACF) after discectomy and/or corpectomy is a common procedure with traditionally good patient outcomes. Though typically mild, postoperative dysphagia can result in significant patient morbidity. In this study, we examine the relationship between postoperative dysphagia and in-hospital outcomes, readmissions, and overall costs. The University HealthSystem Consortium (UHC) database was utilized to perform a retrospective cohort study of all adults who underwent a principal procedure of ACF of the anterior column (International Classification of Diseases, Ninth Revision [ICD-9] procedure code 81.02) between 2013 and 2015. Patients with a diagnosis of dysphagia (ICD-9 78720-78729) were compared to those without. Patient demographics, length of stay, in-hospital mortality, 30-day readmissions, and direct costs were recorded. A total of 49,300 patients who underwent ACF were identified. Mean age was 54.5years and 50.2% were male. Dysphagia was documented in 3,137 patients (6.4%) during their hospital stay. Patients with dysphagia had an average 2.1 comorbidities, while patients without dysphagia had 1.5 (p<0.01). Mean length of stay was 6.38days in patients with dysphagia, and 2.13days in those without (p<0.01). In-hospital mortality was 0.10% in patients without dysphagia, and 0.61% in those with dysphagia (p<0.01). Direct costs were $13,099 in patients without dysphagia, and $21,245 in those with dysphagia (p<0.01). Thirty-day readmission rate was 2.9% in patients without dysphagia, and 5.3% in those with dysphagia (p=0.01). In summary, dysphagia in patients who undergo ACF correlates with significantly increased length of stay, 30-day readmissions, and in-hospital mortality. Direct costs are similarly increased as a result.

  15. Anterior cervical discectomy and fusion: Comparison of titanium and polyetheretherketone cages

    Directory of Open Access Journals (Sweden)

    Cabraja Mario

    2012-09-01

    Full Text Available Abstract Background Titanium (TTN cages have a higher modulus of elasticity when compared with polyetheretherketone (PEEK cages. This suggests that TTN-cages could show more frequent cage subsidence after anterior cervical discectomy and fusion (ACDF and therefore might lead to a higher loss of correction. We compared the long term results of stand-alone PEEK- and TTN-cages in a comparable patient collective that was operated under identical operative settings. Methods From 2002 to 2007 154 patients underwent single-level ACDF for degenerative disc disease (DDD. Clinical and radiological outcome were assessed in 86 eligible patients after a mean of 28.4 months. 44 patients received a TTN- and 42 patients a PEEK-cage. Results Solid arthrodesis was found in 93.2% of the TTN-group and 88.1% of the PEEK-group. Cage subsidence was observed in 20.5% of the TTN- and 14.3% of the PEEK-group. A significant segmental lordotic correction was achieved by both cage-types. Even though a loss of correction was found at the last follow-up in both groups, it did not reach the level of statistical significance. Statistical analysis of these results revealed no differences between the TTN- and PEEK-group. When assessed with the neck disability index (NDI, the visual analogue scale (VAS of neck and arm pain and Odom’s criteria the clinical data showed no significant differences between the groups. Conclusions Clinical and radiological outcomes of ACDF with TTN- or PEEK-cages do not appear to be influenced by the chosen synthetic graft. The modulus of elasticity represents only one of many physical properties of a cage. Design, shape, size, surface architecture of a cage as well as bone density, endplate preparation and applied distraction during surgery need to be considered as further important factors.

  16. Postoperative dysphagia correlates with increased morbidity, mortality, and costs in anterior cervical fusion.

    Science.gov (United States)

    Joseph, Jacob R; Smith, Brandon W; Mummaneni, Praveen V; La Marca, Frank; Park, Paul

    2016-09-01

    Anterior cervical fusion (ACF) after discectomy and/or corpectomy is a common procedure with traditionally good patient outcomes. Though typically mild, postoperative dysphagia can result in significant patient morbidity. In this study, we examine the relationship between postoperative dysphagia and in-hospital outcomes, readmissions, and overall costs. The University HealthSystem Consortium (UHC) database was utilized to perform a retrospective cohort study of all adults who underwent a principal procedure of ACF of the anterior column (International Classification of Diseases, Ninth Revision [ICD-9] procedure code 81.02) between 2013 and 2015. Patients with a diagnosis of dysphagia (ICD-9 78720-78729) were compared to those without. Patient demographics, length of stay, in-hospital mortality, 30-day readmissions, and direct costs were recorded. A total of 49,300 patients who underwent ACF were identified. Mean age was 54.5years and 50.2% were male. Dysphagia was documented in 3,137 patients (6.4%) during their hospital stay. Patients with dysphagia had an average 2.1 comorbidities, while patients without dysphagia had 1.5 (p<0.01). Mean length of stay was 6.38days in patients with dysphagia, and 2.13days in those without (p<0.01). In-hospital mortality was 0.10% in patients without dysphagia, and 0.61% in those with dysphagia (p<0.01). Direct costs were $13,099 in patients without dysphagia, and $21,245 in those with dysphagia (p<0.01). Thirty-day readmission rate was 2.9% in patients without dysphagia, and 5.3% in those with dysphagia (p=0.01). In summary, dysphagia in patients who undergo ACF correlates with significantly increased length of stay, 30-day readmissions, and in-hospital mortality. Direct costs are similarly increased as a result. PMID:27234612

  17. Recurrent laryngeal nerve injury following reoperative anterior cervical discectomy and fusion: a meta-analysis.

    Science.gov (United States)

    Erwood, Matthew S; Hadley, Mark N; Gordon, Amber S; Carroll, William R; Agee, Bonita S; Walters, Beverly C

    2016-08-01

    OBJECTIVE Recurrent laryngeal nerve (RLN) injury is one of the most frequent complications of anterior cervical discectomy and fusion (ACDF) procedures. The frequency of RLN is reported as 1%-11% in the literature. (4 , 15) The rate of palsy after reoperative ACDF surgery is not well defined. This meta-analysis was performed to review the current medical evidence on RLN injury after ACDF surgery and to determine a relative rate of RLN injury after reoperative ACDF. METHODS MEDLINE, PubMed, and Google Scholar searches were performed using several key words and phrases related to ACDF surgery. Included studies were written in English, addressed revisionary ACDF surgery, and studied outcomes of RLN injury. Statistical analysis was then performed using a random-effects model to calculate a pooled rate of RLN injury. The heterogeneity of the studies was assessed using Cochran's Q statistic and I(2) statistic, and a funnel plot was constructed to evaluate publication bias. RESULTS The search initially identified 345 articles on this topic. Eight clinical articles that met all inclusion criteria were included in the meta-analysis. A total of 238 patients were found to have undergone reoperative ACDF. Thirty-three of those patients experienced an RLN injury. This analysis identified a rate of RLN injury in the literature after reoperative ACDF of 14.1% (95% confidence interval [CI] 9.8%-19.1%). CONCLUSIONS The rate of RLN palsy of 14.1% was greater than any published rate of RLN injury after primary ACDF operations, suggesting that there is a greater risk of hoarseness and dysphagia with reoperative ACDF surgeries than with primary procedures as reported in these studies. PMID:27015129

  18. MAST QUADRANT 可扩张管下单侧椎弓根钉置入与椎体间融合治疗腰椎退变性疾病%Recent clinical observation in treatment of lumbar degenerative diseases with posterior lumbar interbody fusion cage and pedicle screw fixation under MAST QUADRANT expansive pipe

    Institute of Scientific and Technical Information of China (English)

    孙郁雨; 崔志明; 保国锋; 李卫东; 徐冠华; 王玲玲; 崔颖; 储惊蛰

    2011-01-01

    背景:腰椎后路椎体间融合治疗腰椎退变性疾病,能够恢复椎间隙高度、维持腰椎生理前凸、提供腰椎的即刻稳定性及取得较高的椎间骨性融合率.目的:验证运用MAST QUADRANT 可扩张管通道微创系统行单侧椎弓根钉置入并椎体间融合治疗腰椎退变性疾病的适应证及有效性.方法:在3.0 cm的微创切口内放置MAST QUADRANT可扩张管,应用单侧椎弓根钉内固定加椎体间融合治疗腰椎退变性疾病患者32例.结果与结论:患者置入内固过程中未发生硬膜囊撕裂、神经根和大血管等副损伤.随访3个月以上.置入3个月后JOA评分明显高于置入前(P < 0.01),目测类比评分显著低于置入前(P < 0.01).X射线片显示椎间隙骨密度均逐渐增加,未发现椎间融合器移位、假关节、内固定松脱或折断等并发症,亦无炎症、过敏等不良反应.%BACKGROUND: Posterior lumbar interbody fusion for lumbar degenerative disease can restore disc height, maintain the lumbar lordosis, provide immediate stability for the lumbar spine and achieve a higher rate of interbody bonefusion. OBJECTIVE: To explore the indications, surgical techniques and early curative effects in treatment of lumbar degenerative diseases with posterior lumbar interbody fusion cage and pediclescrew fixation under MAST QUADRANT expansive pipe. METHODS: Thirty-two cases suffering from lumbar degenerative diseases were treated by posterior lumbar interbody fusion cage and unilateral pedicle screw fixation with MAST QUADRANT expansive pipe which was placed in 3.0 cm minimally invaswe incision.RESULTS AND CONCLUSION: Therewere no epidural capsuletear, injury of nerve root and great vessel after reatment. Postoperative follow up continued over 3 months. Compared with preoperation. JO As core difference had statistical significance at 3 months after operation (P < 0.01). VAS score difference also had statistical significance at 3 months after operation (P< 001

  19. 单侧椎弓根螺钉内固定联合单枚融合器治疗极外侧腰椎间盘突出症%Unilateral pedicle screw fixation combined with single cage interbody fusion for far lateral lumbar disc herniation

    Institute of Scientific and Technical Information of China (English)

    王佳; 周耀; 李伟; 杨方

    2013-01-01

    Objective To evaluate the surgical results of treating far lateral lumbar disc herniations by lumbar inter-body fusion with unilateral pedicle screw fixation and single cage. Methods 26 cases of far lateral lumbar disc herniations were received the treatment of lumbar interbody fusion with unilateral pedicle screw fixation and single cage via a posterior approach. X-ray or CT examinations were taken in the regular follow-up to observe the fusion rates and complications, and the outcome of the surgery was assessed by Japanese Orthopaedic Association ( JOA ) low back pain scores. Results There were no wound infection or nerve complications after operation. All patients were followed up for 18 ~27 months. The fusion rate was 96. 2%( 25/26 ). The average JOA scores of preoperation and final followed-up were 12. 43 2. 16 and 24. 53 2. 97 respectively, which showed significant difference ( P <0. 05 ) between the two observations. The mean improvement rate was 81. 6% , and 19 cases got excellent results,5 good and 2 fair. The excellent and good rate was 92. 3%( 24/26 ). Conclusions Lumbar interbody fusion with unilateral pedicle screw fixation combined with single cage can provide simple procedure, little trauma, reliable fixation, high fusion rate, and satisfactory clinical results.%目的 评估单侧椎弓根螺钉内固定联合单枚融合器治疗极外侧腰椎间盘突出症的疗效.方法 对26例极外侧腰椎间盘突出症患者经腰椎后路行单侧椎弓根螺钉内固定联合单枚cage的融合手术.术后定期复查X线片或CT片,观察融合率及并发症情况;采用JOA腰腿痛评分法评估疗效.结果 术后均无伤口感染、神经损伤.患者均获随访,时间18~27个月.临床融合率96.2%(25/26).JOA评分:术前为12.43分±2.16分,末次随访时为24.53分±2.97分,差异有统计学意义(P<0.05),平均改善率为81.6%.疗效评定:优19例,良5例,中2例,优良率92.3%(24/26).结论 单侧椎弓根螺钉内固定联合单

  20. Laminoplasty versus laminectomy and fusion for multilevel cervical myelopathy: a meta-analysis of clinical and radiological outcomes.

    Science.gov (United States)

    Lee, Chang-Hyun; Lee, Jaebong; Kang, James D; Hyun, Seung-Jae; Kim, Ki-Jeong; Jahng, Tae-Ahn; Kim, Hyun-Jib

    2015-06-01

    OBJECT Posterior cervical surgery, expansive laminoplasty (EL) or laminectomy followed by fusion (LF), is usually performed in patients with multilevel (≥ 3) cervical spondylotic myelopathy (CSM). However, the superiority of either of these techniques is still open to debate. The aim of this study was to compare clinical outcomes and postoperative kyphosis in patients undergoing EL versus LF by performing a meta-analysis. METHODS Included in the meta-analysis were all studies of EL versus LF in adults with multilevel CSM in MEDLINE (PubMed), EMBASE, and the Cochrane library. A random-effects model was applied to pool data using the mean difference (MD) for continuous outcomes, such as the Japanese Orthopaedic Association (JOA) grade, the cervical curvature index (CCI), and the visual analog scale (VAS) score for neck pain. RESULTS Seven studies comprising 302 and 290 patients treated with EL and LF, respectively, were included in the final analyses. Both treatment groups showed slight cervical lordosis and moderate neck pain in the baseline state. Both groups were similarly improved in JOA grade (MD 0.09, 95% CI -0.37 to 0.54, p = 0.07) and neck pain VAS score (MD -0.33, 95% CI -1.50 to 0.84, p = 0.58). Both groups evenly lost cervical lordosis. In the LF group lordosis seemed to be preserved in long-term follow-up studies, although the difference between the 2 treatment groups was not statistically significant. CONCLUSIONS Both EL and LF lead to clinical improvement and loss of lordosis evenly. There is no evidence to support EL over LF in the treatment of multilevel CSM. Any superiority between EL and LF remains in question, although the LF group shows favorable long-term results. PMID:25815808

  1. A computed tomography morphometric study of occipital bone and C2 pedicle anatomy for occipital-cervical fusion

    Directory of Open Access Journals (Sweden)

    Nicolas K.K. King

    2014-01-01

    Full Text Available Background: Occipital-cervical fusion (OCF has been used to treat instability of the occipito-cervical junction and to provide biomechanical stability after decompressive surgery. The specific areas that require detailed morphologic knowledge to prevent technical failures are the thickness of the occipital bone and diameter of the C2 pedicle, as the occipital midline bone and the C2 pedicle have structurally the strongest bone to provide the biomechanical purchase for cranio-cervical instrumentation. The aim of this study was to perform a quantitative morphometric analysis using computed tomography (CT to determine the variability of the occipital bone thickness and C2 pedicle thickness to optimize screw placement for OCF in a South East Asian population. Methods: Thirty patients undergoing cranio-cervical junction instrumentation during the period 2008-2010 were included. The thickness of  the occipital bone and the length and diameter of the C2 pedicle were measured based on CT. Results: The thickest point on the occipital bone was in the midline with a maximum thickness below the external occipital protuberance of 16.2 mm (±3.0 mm, which was thicker than in the Western population. The average C2 pedicle diameter was 5.3 mm (±2.0 mm. This was smaller than Western population pedicle diameters. The average length of the both pedicles to the midpoint of the C2 vertebral body was 23.5 mm (±3.3 mm on the left and ±2.3 mm on the right. Conclusions: The results of this first study in the South East Asian population should help guide and improve the safety in occipito-cervical region instrumentation. Thus reducing the risk of technical failures and neuro-vascular injury.

  2. Laminoplasty versus laminectomy and fusion for multilevel cervical myelopathy: a meta-analysis of clinical and radiological outcomes.

    Science.gov (United States)

    Lee, Chang-Hyun; Lee, Jaebong; Kang, James D; Hyun, Seung-Jae; Kim, Ki-Jeong; Jahng, Tae-Ahn; Kim, Hyun-Jib

    2015-06-01

    OBJECT Posterior cervical surgery, expansive laminoplasty (EL) or laminectomy followed by fusion (LF), is usually performed in patients with multilevel (≥ 3) cervical spondylotic myelopathy (CSM). However, the superiority of either of these techniques is still open to debate. The aim of this study was to compare clinical outcomes and postoperative kyphosis in patients undergoing EL versus LF by performing a meta-analysis. METHODS Included in the meta-analysis were all studies of EL versus LF in adults with multilevel CSM in MEDLINE (PubMed), EMBASE, and the Cochrane library. A random-effects model was applied to pool data using the mean difference (MD) for continuous outcomes, such as the Japanese Orthopaedic Association (JOA) grade, the cervical curvature index (CCI), and the visual analog scale (VAS) score for neck pain. RESULTS Seven studies comprising 302 and 290 patients treated with EL and LF, respectively, were included in the final analyses. Both treatment groups showed slight cervical lordosis and moderate neck pain in the baseline state. Both groups were similarly improved in JOA grade (MD 0.09, 95% CI -0.37 to 0.54, p = 0.07) and neck pain VAS score (MD -0.33, 95% CI -1.50 to 0.84, p = 0.58). Both groups evenly lost cervical lordosis. In the LF group lordosis seemed to be preserved in long-term follow-up studies, although the difference between the 2 treatment groups was not statistically significant. CONCLUSIONS Both EL and LF lead to clinical improvement and loss of lordosis evenly. There is no evidence to support EL over LF in the treatment of multilevel CSM. Any superiority between EL and LF remains in question, although the LF group shows favorable long-term results.

  3. Safety and efficacy of rhBMP2 in posterior cervical spinal fusion for subaxial degenerative spine disease: Analysis of outcomes in 204 patients

    OpenAIRE

    Xu, Risheng; Bydon, Mohamad; Sciubba, Daniel M.; Witham, Timothy F.; Wolinsky, Jean-Paul; Gokaslan, Ziya L; Bydon, Ali

    2011-01-01

    Background: Many studies offer excellent demonstration of the ability of bone morphogenic protein (BMP) to enhance fusion rates in anterior as well as posterior lumbar surgery. Recently, BMP has also been shown to increase arthrodesis rates in anterior cervical surgery, albeit with concomitant increases in complication rates. To date, however, few studies have investigated the safety and efficacy of BMP in cervical surgeries approached posteriorly. Methods: We retrospectively reviewed 204 con...

  4. Treatment of lumbar degenerative disease with modified transforaminal lumbar interbody fusion%改良经椎间孔椎体间融合术治疗腰椎退变性疾病

    Institute of Scientific and Technical Information of China (English)

    刘阳; 杨群; 唐开; 马凯; 姜长明; 吴春明; 王宏

    2011-01-01

    目的 探讨改良经椎间孔椎体间融合术治疗腰椎退变性疾病的临床疗效.方法 2007年6月至2009年5月对62例腰椎退变性疾病患者行改良经单侧椎间孔椎体间植骨融合,相应节段椎弓根钉内固定术.其中腰椎间盘突出合并腰椎不稳28例,腰椎间盘突出合并椎管狭窄27例,退变性滑脱7例.累及单节段48例,累及双节段14例.通过观察融合情况,记录术前、术后3个月和末次随访时的视觉模拟评分(VAS)和日本矫形外科学会(JOA)评分判定治疗效果.结果 62例患者均获得随访,随访时间15~30(22.77±3.82)个月.无神经损伤、脑脊液漏、感染及椎弓根钉断裂等并发症.术后1年椎体间融合率为96.8%.依据JOA评分,优34例,良24例,可4例,差0例,优良率为93.5%(58/62).术后VAS和JOA评分与术前比较差异有统计学意义(P<0.05),术后3个月VAS和JOA评分与末次随访时比较差异无统计学意义(P>0.05).结论 改良经椎间孔椎体间融合术在充分减压同时能减少进入椎管带来的并发症,临床疗效好,是治疗腰椎退变性疾病的有效术式.%Objective To investigate the chnical effect of modified transforaminal lumbar interbody fusion (TLIF) on the treatment of lumbar degenerative disease. Methods Sixty-two patients with lumbar degenerative disease were treated by the modified TLIF from June 2007 to May 2009. The preoperative diagnosis was lumbar intervertebral disc herniation with spinal instability (28 cases), lumbar intervertebral disc herniation with lumbar stenosis (27 cases ), degenerative spondylohsthesis (7 cases ). Forty-eight cases were single-level and 14 cases were two-level. The patients were evaluated by observing the fusion rate and comparing the visual analog score( VAS ) and Japanese orthopaedics association (JOA) score of preoperation with those of postoperation. Results All the patients were followed up from 15 to 30 (22.77 ± 3.82)months,no nerve injury,leakage of

  5. Clinical study on lumbar spondylolisthesis treated by minimally invasive transforaminal lumbar interbody fusion%微创经椎间孔腰椎体间融合术治疗腰椎滑脱症的临床研究

    Institute of Scientific and Technical Information of China (English)

    王建; 黄博; 周跃; 张正丰; 李长青; 任先军; 初同伟; 王卫东; 郑文杰; 潘勇

    2011-01-01

    目的 回顾性分析和比较微创经椎间孔腰椎间融合术(MIS-TLIF)和开放经椎间孔腰椎间融合术(OTLIF)治疗腰椎滑脱症的临床结果.方法 自2006年6月至2010年5月,371例Ⅰ°或Ⅱ°腰椎滑脱症患者接受TLIF和腰椎弓根螺钉固定治疗并获得随访,男性134例,女性237例;年龄37~85岁,平均50.4岁.采用可扩张通道下单节段TLIF和经皮椎弓根螺钉内固定治疗患者172例(MIS-TLIF组),传统开放TLIF和椎弓根螺钉内固定方法治疗患者199例(OTLIF组).分析两组手术时间、术中术后出血、放射线暴露时间和并发症等方面的差异.采用视觉模拟评分( VAS)和Oswestry功能障碍指数(ODI)评分评估临床结果,行腰椎动力位X线片和薄层CT扫描重建检查评价椎间融合情况.结果 371例患者均获得随访,随访时间12~ 58个月,平均32.7个月.术前两组性别、年龄、滑脱类型和融合节段差异无统计学意义.术中出血MIS-TLIF组平均为(310±75)ml,OTLIF组(623±156)ml,MIS-TLIF组显著优于OTLIF组(t=2.836,P<0.01).术后出血MIS-TLIF组平均为(38±13)ml,OTLIF组(184±72)ml,MIS-TLIF组显著优于OTLIF组(=3.274,P<0.01).与OTLIF组放射暴露时间(20±10)s比较,MIS-TLIF组放射暴露时间(51±19)s更长(t=2.738,P<0.01).两组在手术时间、腰痛VAS评分、ODI评分和并发症发生方面差异均无统计学意义.结论 针对Ⅱ°以下腰椎滑脱症,MIS-TLIF安全有效,相对而言,与开放固定比较具有出血少及组织损伤轻优点.%Objectives To retrospectively analyze the treatment of lumbar spondylolisthesis using minimally invasive and open transforaminal lumbar interbody fusion (TLIF),and compare the clinical results of two techniques.Methods From June 2006 to May 2010,371 patients with lumbar spondylolisthesis grade 1 and 2 were treated with TLIF,pedicle screw fixation and followed up.The mean age was 50.4 years (range,37-85 years).There were 172 patients who underwent minimally

  6. Impact of Age and Duration of Symptoms on Surgical Outcome of Single-Level Microscopic Anterior Cervical Discectomy and Fusion in the Patients with Cervical Spondylotic Radiculopathy

    Directory of Open Access Journals (Sweden)

    Farzad Omidi-Kashani

    2014-01-01

    Full Text Available We aim to evaluate the impact of age and duration of symptoms on surgical outcome of the patients with cervical spondylotic radiculopathy (CSR who had been treated by single-level microscopic anterior cervical discectomy and fusion (ACDF. We retrospectively evaluated 68 patients (48 female and 20 male with a mean age of 41.2±4.3 (ranged from 24 to 72 years old in our Orthopedic Department, Imam Reza Hospital. They were followed up for 31.25±4.1 months (ranged from 25 to 65 months. Pain and disability were assessed by Visual Analogue Scale (VAS and Neck Disability Index (NDI questionnaires in preoperative and last follow-up visits. Functional outcome was eventually evaluated by Odom’s criteria. Surgery could significantly improve pain and disability from preoperative 6.2±1.4 and 22.2±6.2 to 3.5±2.0 and 8.7±5.2 (1–21 at the last follow-up visit, respectively. Satisfactory outcomes were observed in 89.7%. Symptom duration of more and less than six months had no effect on surgical outcome, but the results showed a statistically significant difference in NDI improvement in favor of the patients aged more than 45 years (P=0.032, although pain improvement was similar in the two groups.

  7. Quadrant 单侧固定椎间融合治疗不稳定型腰椎间盘突出症%Unilateral Pedicle Screw Fixation and Interbody Fusion for the Treatment of Lumbar Disc Hernia-tion with Lumbar Spinal Instability under Mast Quadrant System

    Institute of Scientific and Technical Information of China (English)

    李青; 姚海燕; 梁道臣; 赵成毅; 张爱明; 梅治; 陈应超; 张非

    2014-01-01

    Objective To explore the clinical outcome of the minimally invasive surgical approach by mast Quadrant sys-tem in the treatment of lumbar disc herniation with lumbar spinal instability. Methods For 31 patients with single level lum-bar disc herniation with lumbar spinal instability which diagnosed by magnetic resonance imaging and dynamic X-rays. This group included 20 males and 11 females. All patients were managed by unilateral pedicle screw fixation and interbody fusion under Mast Quadrant system. We evaluate the therapeutic effect according to Japanese Orthopaedic Association(JOA)and Os-westry disability index(ODI)before and after surgery. X-rays was used to evaluate the height variation and fusion of interverte-bral space. Results All patients were followed up for 14 to 36 months,with a mean period of 20. 4 months. The symptoms of lumbar and lower extremity were relieved completely. There was no decrease of intervertebral height. Radiographic interbody fu-sion rate was 100% . According to JOA scoring,the score increased from(7. 6 ± 2. 5)before operation to(25. 7 ± 1. 4)in the last follow-up,improvement rate of treatment was 84. 46% ,the score of ODI decreased from(55. 5 ± 5. 2)to(10. 9 ± 3. 0)in the last follow up after surgery. Conclusion The minimally invasive surgical treatment of unilateral pedicle screw fixation and interbody fusion assisted mast Quadrant system for lumbar disc herniation with lumbar spinal instability is reliable and provides satisfactory lumbar fusion and clinical results.%目的:探讨在 MastQuadrantTM 可扩张管通道系统下单侧固定加 Cage 治疗腰椎间盘突出症伴腰椎不稳的临床疗效。方法对31例腰椎间盘突出症伴腰椎不稳患者,采用 Quadrant 微创下单侧固定加 Cage 椎间融合术治疗,其中男20例,女11例;年龄34~76岁。术前、术后采用日本骨科学会(Japanese orthopaedic association,JOA)腰背痛评分及 Oswestry 功能障碍指数(oswestry disability

  8. Radiographic properties and applied anatomy of presacral space in percutaneous axial lumbosacral interbody fusion%经皮前路腰骶轴向融合的骶前影像学及解剖学研究

    Institute of Scientific and Technical Information of China (English)

    靳松; 彭建强; 徐宏光; 刘平; 陈学武; 李怀斌

    2012-01-01

    Objective:To examine the radiologir and neurovascular ana-tomic data of the presacral area in Chinese population for safe procedure in percutaneous axial lumbosacral interbody fusion(AxiaLIF). Methods : ①Radiographic data were reviewed in 68 outpatients with low back pain undergone enhanced CT scanning. Measurements included bilateral iliac vessels to the S1,2 , the midpoint of the 2 clearance distance as well as lumbosacral MRI midsagittal chip measurement of the lumbosacral inter-vertebral space and each vertebral body point by the minimum distance of mesorectum. ② Anatomical aspects: 25 adult cadaveric specimens were included by measurement of internal / external iliac vessels, median sacral vein to S1,2 spaces at the midpoint of the distance and S1 distance between and nerve to determine coronal "safe zone" for operation. Results ATT images displayed the minimum distance of S1,2 space midline by the closest vessels with bilateral internal iliac vein. The reach within the bilateral internal iliac veins was(57. 7 ±4. 9)mm for men and(70.10 ± 9. 0) mm for women(P<0.05). MRI measurement exhibited the minimum distance between mesorectum and individual sacral anterior boder margin with median measurement of 10(3 -23)mm in males and 6(3 - 18)mm in females(P<0.01). Anatomical data revealed the "safe zone" for operation by(57. 60 ± 5. 11) mm in men and (70.01 ± 8. 99) mm in women,respectively. The distance between inner margin of bilateral ante-rior sacral foramina at the level of SI was(34. 95 ± 3. 50) mm for males and(31. 98 ± 2.99) mm for females. No difference was seen in the median sacral artery, whereas the median sacral veins varied a lot with thinner wall and existence rate of 48% . Conclusion : The measurement data for "safe zone" operation are in relative match in radiographic findings with anatomic measurement, which can be served as reference parameter for development of instrumentation and fusion device for bone surgery in Chinese population

  9. Comparison of clinical efficacy of minimally invasive versus open transforaminal lumbar interbody fusion with unilat-eral pedicle screw fixation for lumbar disc herniation%单侧微创与开放经椎间孔腰椎椎体间融合内固定治疗腰椎椎间盘突出症的临床疗效比较

    Institute of Scientific and Technical Information of China (English)

    井贵龙; 袁峰; 郭开今; 孙玛骥

    2014-01-01

    Objective To compare the clinical effect of minimally invasive versus open transforaminal lumbar interbody fusion with unilateral pedicle screw fixation for lumbar disc herniation.Methods The data of 54 patients with lumbar disc herniation who were a-dopted from October 2009 to October 2012 were retrospectively analyzed.There were 32 males and 22 females, and the mean age was 42. 7 years (rang, 32-60 years).The level of surgery was L4/L5 in 34 patients,L5/S1 in 20 patients.All patients were divided into 2 groups according to the surgical methods, including 30 patients undergoing open transforaminal lumbar interbody fusion (OTLIF) and 24 patients undergoing minimally invasive transforaminal lumbar interbody fusion(MiTLIF).The operation time, intraoperative and postoperative blood loss, length of hospital-stay, intraoperative and postoperative complications were recorded .Intervertebral fusion rates 1 year after the operation were observed by radiographic data.Japanese Orthopaedic Association (JOA) scores were used for assessment.Results All patients were followed up for a mean period of 21.4 months (range, 12-36 months).In the MiTLIF group, the intraoperative andpostoperative blood loss was (40.2±15.6) mL, the length of hospital-stay was (6.2 ±2.4) d.Two weeks after the operation, the JOAscore was 18.7±1.9.In the OTLIF group, the intraoperative and postoperative blood loss was (203.6 ±52.8) mL, the length of hospital-stay was (10.8±4.2) d.Two weeks after the operation, the JOA score was 15.1 ±1.4.The difference between the 2 groups werestatistically significant (P 0.05). Conclusion The MiTLIF has the advantages of less blood loss, shorter hospitalization time and rapid postoperative recovery in thetreatment of lumbar disc herniation with unilateral pedicle screw fixation.%目的:比较微创经椎间孔融合内固定与传统开放经椎间孔融合内固定术治疗腰椎椎间盘突出症的临床疗效。方法2009年10月~2012年10月,对54例腰

  10. Segmental anterior cervical decompression with fusion for treating multilevel cervical myelopathy%颈前路分节段减压融合治疗多节段颈椎病

    Institute of Scientific and Technical Information of China (English)

    林昊; 何仿; 李健; 崔庆元; 陈小强; 田纪伟

    2011-01-01

    Objective To evaluate the clinical value of the segmental anterior cervical decompression with fusion for treating multilevel cervical myelopathy.Methods 24 patients of multilevel cervical myelopathy with 3 or 4 consecutive segments were treated with segmental anterior cervical decompression with fusion.All patientst' cervical plain films,magnetic resonance imaging( MRI ) on preoperation and cervical plain films on postoperation were ohserved.The JOA scores of preoperation and 3 months postoperatively were collected.Results 24 cases were followed up from 3 months to 48 months, average 28 months.All patients improved their functional status in different degree.No complications such as graft nonunion and graft suhsidence occurred.The mean preoperative JOA score of all patients was ( 8.20 ±2.26 ),the postoperative of 3 months was ( 13.50 ± 1.28 ) , the average JOA recovery rate was 60.2%.Fusion rate was 100%.Conclusions The segmental anterior cervical decompression with fusion for treating multilevel cervical myelopathy appears to be effective in decompressing spinal cord, improving nerve functional status and restoring lordosis to the cervical spine with high fusion rate and fewer complications.%目的 评价颈前路分节段减压植骨融合术治疗多节段颈椎病的临床疗效.方法 对24例连续3或4个节段病变的颈椎病患者采用分节段减压融合术治疗.均行术前X线、MRI和术后X线片检查.均于术前及术后3个月进行JOA评分.结果 24例均获随访,时间3~48(28±20)个月.患者功能均有不同程度的改善.无植骨块不愈合、内置物下沉等并发症发生.JOA评分术前平均为(8.20±2.26)分,术后3个月平均为(13.50±1.28),改善率为60.2%,植骨融合率100%.结论 颈椎前路分节段减压融合术具有减压彻底、术后神经功能恢复好、恢复颈椎曲度、融合率高、并发症少等优点.

  11. Adjacent segment disease after anterior cervical decompression and fusion: analysis of risk factors on X-ray and magnetic resonance imaging

    Institute of Scientific and Technical Information of China (English)

    Zhao Yanbin; Sun Yu; Zhou Feifei; Wang Shaobo; Zhang Fengshan; Pan Shengfa

    2014-01-01

    Background Adjacent segment disease (ASD) is common after cervical fusion.The aim of this study was to evaluate the risk factors for ASD on X-ray and magnetic resonance imaging (MRI).Methods Patients included in this study had received revision surgeries after developing symptomatic ASD following anterior decompression and fusion.A control group that had not developed ASD was matched 1:1 by follow-up time and fusion segments.Plate-to-disc distances (PDDs),developmental cervical canal stenosis on X-ray,cervical disc degeneration grading,and cervical disc bulge impingements on preoperative MRI were measured and compared between the ASD group and the control group.Results Thirty-four patients with complete radiographic data were included in the ASD group.The causative segments of ASD included nine cases of C3-4,18 cases of C4-5,three cases of C5-6,and four cases of C6-7.The ASD occurred at the upper adjacent segments in 26 patients and at the lower adjacent segments in eight patients.PDD distributions were similar between the ASD group and the control group.Developmental cervical canal stenosis was a risk factor for ASD,with an odd ratio value of 2.88.Preoperative cervical disc degenerations on MRI were similar between the ASD group and the control group.In the upper-level ASD group,the disc bulge impingement was (19.7±9.7)%,which was significantly higher than that of the control group of (11.8±4.8)%.Conclusions ASD was more likely to develop above the index level of fusion.Developmental cervical canal stenosis and greater disc bulge impingement may be risk factors for the development of ASD.

  12. Significant relationship between local angle at fused segments and C2-7 angle: Average duration of longer than 20 years after anterior cervical discectomy and fusion

    Directory of Open Access Journals (Sweden)

    T Nagata

    2011-01-01

    Full Text Available Background : The authors have focused their attention to the radiological durability of cervical sagittal alignment after anterior cervical discectomy and fusion (ACDF using autologous bone grafting. Materials and Methods : Among the patients who underwent ACDF with trans-unco-discal (TUD approach between 1976 and 1997, 22 patients (16 males and 6 females made return visits for a clinical evaluation. Patients with trauma or previously treated by anterior cervical fusion or by posterior decompression were excluded from the present study. Clinical evaluation included adjacent segment degeneration (ASD, osseous fusion, local angle at the fused segments and C2-7 angle of cervical spine. Results : The duration after ACDF ranged from 13 to 34 years with an average of 21.3 ± 7.0 years. A single level fusion was done on 8 patients, 2 levels on 11 patients, 3 levels on 2 patients, and 4 levels on 1 patient. Imaging studies indicated that 12 of the 22 patients (54.5% were graded as having symptomatic ASD. Osseous bony fusion at ACDF was recognized in all cases. None of the patients demonstrated kyphotic malalignment of the cervical spine. Average degrees of local angle at the fused segments and the C2-7 angle were 7.06 and 17.6, respectively. Statistical analysis indicated a significant relationship between the local at the fused segments and C2-7 angles. Conclusions : Sagittal alignment of the cervical spine was durable long after ACDF when the local angle at the fused segments was well stabilized.

  13. 下颈椎骨折脱位修复方法的选择:植骨融合及颈椎稳定性分析%Restoration of fracture and dislocation of lower cervical spine:bone graft fusion and cervical stability

    Institute of Scientific and Technical Information of China (English)

    王建元; 邓强; 盛伟斌; 陆永江

    2015-01-01

    of grade A were not recovered, one case of grade B was not recovered, 1-2 degree of neurological function recovery was achieved in the remaining cases by Frankel system. X-ray finding showed the good recovery of cervical vertebrae sequence after operation. Fusion was achieved in al cases within 12 months (mean 8.5 months) except non-fusion in one case and delayed fusion in two cases. There was no pseudarthrosis or nonunion occurred. The interbody height, physiological curvature and cervical stability maintained wel. The SLIC system, with a combination of sub-axial injury classification system, the type of fracture, spinal cord compression, and cervical spine injury degree should be considered before surgery. Reasonable selection of surgical approach can reconstruct spinal stability and achieve anatomical reduction and complete decompression, which is conducive to the recovery of neurological function.%背景:下颈椎骨折脱位的治疗难点是如何改善患者的神经功能,选择手术入路应既有利于复位及脊髓的减压,又能够保证坚强固定,植骨融合。目前对下颈椎骨折脱位的术式选择仍存在较大分歧。  目的:探讨下颈椎骨折脱位的修复方式选择及其对植骨融合、颈椎稳定性的影响。  方法:收集新疆医科大学第一附属医院2009年1月至2013年9月收治的下颈椎骨折脱位患者126例,按照Frankel分级标准进行分级:A级7例,B级48例,C级54例,D级17例。术前进行下颈椎损伤分类评分,其中4分15例,5分23例,6分25例,7分22例,8分18例,9分16例,10分6例。结合患者受伤机制、形态特点、脊髓受压部位及损伤程度等因素进行分析,选择修复方案,其中前路组91例采用单纯前路手术治疗(单间隙或椎体次全切除减压、椎间植骨钛板内固定);后路组6例行后路减压、复位、内固定;前后联合组29例采用前后联合入路。随访患者神经功能改

  14. Systematic review for the treatment of degenerative diseases with the lumbar posterior lumbar interbody fusion (PLIF) and posterolateral fusion (PLF)%腰椎后路椎体间融合术与后外侧融合术治疗腰椎退行性疾病的系统评价

    Institute of Scientific and Technical Information of China (English)

    崔兆辉; 滕元君; 夏亚一; 汪静; 姜金; 陈少龙

    2013-01-01

    [Objective] To systematically evaluate the effects of posterior lumbar interbody fusion (PLIF) and posterolateral fusion (PLF) for lumbar degenerative disease.[Methods] An electronic search for the eligible randomized controlled trials (RCTs) was conducted in the databases of PubMed,Embase,CNKI,and the Chinese Biomedical Literature Database (CBM).Two researchers independently completed literature selection and data collection,the assessment of methodological quality was conducted in accordance with the Cochrane Handbook 5.1.Meta-analysis was performed using the RevMan 5.1 software.[Results] Six studies involving 487 patients were included.The results of meta-analysis showed that the PLIF had a higher rate of fusion [OR =3.90,95% CI (2.05,7.40),P <0.001] with less ODI score in postoperative 1 year [WMD =-3.86,95%CI (-7.59,-0.13),P=0.04],and both had statistical differences (P<0.05).However,both groups were similar in operation time [WMD =15.85,95% CI (-16.25,47.96),P =0.33],blood loss [WMD =-90.57,95%CI (-292.50,111.36),P=0.38],the rates of complications [OR =0.99,95%CI (0.22,4.47),P=0.99] and secondary surgery [OR =0.87,95% CI (0.52,1.45),P =0.25].[Conclusion] Compared with PLF,the PLIF has a significantly higher rate of fusion with less ODI score in postoperative l year,and there Is no significant difference in operation time,blood loss,the rates of complications and secondary surgery.%[目的]系统评价腰椎后路椎体间融合术(posterior lumbar interbody fusion)对比后外侧融合术(posterolateral fusion)治疗腰椎退行性疾病的术后疗效.[方法]计算机检索PubMed、EMBASE、CNKI、CBM等数据库、学术会议资料和学位论文等.全面收集有关两种方法治疗腰椎退行性疾病的文献.制定文献纳入及排除标准,由2名研究者分别独立筛选文献,按照Cochrane Handbook 5.1进行严格的质量评估,并用Revman 5.2软件进行Meta分析.[结果]经过筛选,共有6篇

  15. 双侧小切口肌间隙入路腰椎椎体间融合治疗下腰椎退行性疾病%Using small incision of dual side and paraspinal approach lumbar interbody fusion for the treatment of lumbar degenerative disease

    Institute of Scientific and Technical Information of China (English)

    方志祥; 李坚; 闫亮; 许海波; 赵建峰

    2012-01-01

    Objective To study the clinical results of lumbar interbody fusion through small incision of dual side and paraspinal approach in the treatment of lumbar degenerative disease. Methods 32 patients who had lumbar degenerative disease underwent single level decompression and lumbar interbody fusion through small incision of dual side paraspinal approach. The operative time, operative blood loss and improvement of clinical symptoms were assessed, visual analogue scores ( VAS ) was used to evaluate the effect of the operation. Results Operation time was 90 ~ f 50 ( 110 ±21 )min, blood loss in the operation was 150~380( 282 ±37 )ml. Incisions were primary healed. All patients were followed up for 7-14 months, the VAS score of two weeks after the operation and the last followed up had statistically significant difference from the scores of the preoperation ( P < 0. 05 ). All cases had bone union and no screws were loosed or broken in the last followe-up, the rate of bone fusion was 100% . Conclusions The lumbar interbody fusion through the small incision of dual side paraspinal approach is an effective method in the treatment of lumbar degenerative disease, which can reduce the blood loss and injury of the soft tissue, accelerate the rehabilitation simultaneously.%目的 评价双侧小切口肌间隙入路腰椎椎体间融合治疗下腰椎退行性疾病的疗效.方法 采用双侧小切口肌间隙入路腰椎椎体间融合结合椎弓根螺钉内固定治疗32例下腰椎退行性疾病患者,观察手术时间、术中出血量及术后症状缓解情况.术前、术后采用视觉模拟疼痛评分(VAS)评价疗效.结果 手术时间90~150(110±21)min,术中出血量150~380(282±37)ml.患者伤口均一期愈合.32例均获随防,时间7~14个月.术后2周及末次随访VAS评分,与术前比较差异均有统计学意义(P<0.05).末次随访椎体间均骨性融合,融合率为100%.未发生螺钉松动、断钉等情况.结论双侧小切口肌

  16. An Outcome Study of Anterior Cervical Discectomy and Fusion among Iranian Population.

    Science.gov (United States)

    Haghnegahdar, Ali; Sedighi, Mahsa

    2016-01-01

    Background and Aim. First-line treatment strategy for managing cervical disc herniation is conservative measures. In some cases, surgery is indicated either due to signs/symptoms of severe/progressive neurological deficits, or because of persistence of radicular pain despite 12 weeks of conservative treatment. Success for treatment of cervical disc herniation using ACDF has been successfully reported in the literature. We aim to determine the outcome of ACDF in treatment of cervical disc herniation among Iranians. Methods and Materials/Patients. In a retrospective cohort study, we evaluated 68 patients who had undergone ACDF for cervical disc herniation from March 2006 to March 2011. Outcome tools were as follows: (1) study-designed questionnaire that addressed residual and/or new complaints and subjective satisfaction with the operation; (2) recent (one week prior to the interview) postoperative VAS for neck and upper extremity radicular pain; (3) Japanese Orthopaedic Association Myelopathy Evaluation Questionnaire (JOACMEQ) (standard Persian version); and (4) follow-up cervical Magnetic Resonance Imaging (MRI) and lateral X-ray. Results. With mean follow-up time of 52.93 (months) ± 31.89 SD (range: 13-131 months), we had success rates with regard to ΔVAS for neck and radicular pain of 88.2% and 89.7%, respectively. Except QOL functional score of JOAMEQ, 100% success rate for the other 4 functional scores of JOAMEQ was achieved. Conclusion. ACDF is a successful surgical technique for the management of cervical disc herniation among Iranian population.

  17. 后路腰椎间融合治疗腰椎管狭窄症患者腰痛的疗效分析%Therapeutic effect of posterior lumbar interbody fusion for treatment of back pain in patients with lumbar stenosis

    Institute of Scientific and Technical Information of China (English)

    王波; 刘海鹰; 王会民; 缪克难; 金朝晖

    2009-01-01

    [Objective] To analyze the causes of back pain in lumbar spinal stenosis and to investigate the therapeutic effect of posterior lumbar interbody fusion (PLIF) for lumbar stenosis with severe back pain. [Methods] The preoperative clinical data on patients with lumbar stenosis and severe back pain were compared with those of patients with typical neurological claudication. The follow - up results of lumbar stenosis with severe low back pain treated by PLIF were analyzed. [ Results] The average age and the rates of segmental instability, degenerative scoliosis, loss of lumbar lordosis in patients with lumbar stenosis and severe back pain were higher than those with lumbar stenosis and typical claudication. After PLIF surgery, the back pain was much relieved, the JOA score was improved , the severity of degenerative scoliosis was reduced, and the lumbar lordosis was restored. Bony fusion was achieved in all operated intervertebral spaces. [Conclusion] PLIF could eliminate various causes due to back pain of lumbar stenosis. PLIF is one of reasonable treatment options for lumbar stenosis with severe low back pain.%[目的]分析腰椎管狭窄症患者腰痛的原因,探讨后路腰椎间融合术对腰椎管狭窄症腰痛的治疗效果.[方法]比较腰痛明显的腰椎管狭窄症患者和典型间歇性跛行症状的腰椎管狭窄症患者的年龄、术前腰椎失稳、生理前凸消失和退变性侧弯的发生率;分析后路腰椎间融合 (posterior lumbar interbody fusion, PLIF) 治疗腰椎管狭窄症患者下腰痛的随访结果.[结果]腰痛明显组的腰椎管狭窄症患者的平均年龄、腰椎节段性失稳率、腰椎前凸消失和退变性侧弯的比率高于间歇性跛行组的腰椎管狭窄症患者.PLIF术后腰痛症状明显减轻,JOA评分改善,退变性侧弯程度减轻,腰椎前凸恢复,椎间均达到骨性融合.[结论]PLIF可消除腰椎管狭窄症的多种腰痛病因,是治疗腰椎管狭窄症下腰痛的较好术式选择.

  18. 经椎间孔椎体间融合术治疗复发性腰椎椎间盘突出症的疗效分析%Transforaminal lumbar interbody fusion for treatment of recurrent lumbar disc herniation: an analysis of therapeutic Effect

    Institute of Scientific and Technical Information of China (English)

    张剑刚; 丁文元; 申勇; 徐佳欣; 安志辉; 杨少坤

    2011-01-01

    Objective To assess the therapeutic effect of transforaminal lumbar interbody fusion ( TLIF ) in treatment of recurrent lumbar disc herniation. Methods From February 2008 to June 2010, 27 patients ( average age 52. 4, ranging 28 ~ 64 years old ) with recurrent lumbar disc herniation, who had been treated by TLIF, were collected in the present study. Japanese Orthopaedic Association ( JOA )score system and Nakai standards were used to evaluate the clinical results. Suk criterion was used to evaluate bone graft fusion. Results All the patients were followed up for 8-36 months ( a mean of 23 months ). According to JOA score system, excellent outcomes were obtained in 20 cases and good in 7, with the average improvement rate being 88. 5%. According to Nakai standard, excellent outcomes were obtained in 18 cases, good in 6 cases, and fair in 3 cases, with the excellent and good rate being 88. 9%. Bone grafts in all patients were fused according to Suk criterion. Conclusion TLIF is an effective procedure for treatment of recurrent lumbar disc herniation; it can obtain satisfactory clinical results.%目的 探讨经椎间孔椎体间融合术(transforaminal lumbar interbody fusion,TLIF)治疗复发性腰椎椎间盘突出症(recurrent lumbar disc herniation,RLDH)的疗效.方法 2008年2月~2010年6月应用TLIF技术再手术治疗的RLDH患者27例,年龄为28~64岁,平均52.4岁.采用日本骨科学会(Japanese Orthopaedic Association,JOA)评分系统、Nakai标准评价治疗效果,Suk方法评价植骨融合情况.结果 患者均获得随访,随访时间为8~36个月(平均23个月).术后根据JOA评分,优20例,良7例,平均改善率88.5%;根据Nakai评分标准,优18例,良6例,可3例,优良率88.9%;根据Suk标准患者椎间植骨均获得骨性融合.结论 TLIF是治疗RLDH的有效术式,可以获得满意临床效果.

  19. 后路内窥镜下髓核摘除术联合椎间融合固定治疗腰椎退变失稳性椎间盘突出症%Posterior endoscopic discectomy combined with lumbar interbody fusion in the treatment of lumbar intervertebral disc protrusion with degenerative lumbar spinal instability

    Institute of Scientific and Technical Information of China (English)

    焦峰; 张强; 纪玉清; 丛伟; 韩磊祥

    2012-01-01

    Objective To discuss the clinical efficacy of posterior endoscopic discectomy combined with expandable spinal spacer (B-Twin) lumbar interbody fusion in the treatment of lumbar intervertebral disc protrusion with degenerative lumbar spinal instability. Methods 22 patients with lumbar intervertebral disc protrusion and degenerative lumbar spinal instability in our hospital from November 2007 to November 2009 were selected. All the patients were treated with posterior endoscopic discectomy combine with B-Twin lumbar interbody fusion. JOA score was used to evaluation before operation, one week after operation and the last follow-up, recovery rate was calculated. Conditions of interbody fusion and disc height height change were observed by X-line and CT during reexamination. Results All 22 patients were smoothly finished operation. The operation time was 70-110 min, average of 83 min; amount of bleeding was 200-400 mL, average of 280 mL. All the patients were followed up for 16-40 months, average of 34.3 months. Average JOA score of before operation was 14.8 scores, which of the last time follow-up was 27.6 scores,the improvement rate was 75%-100%. The reexamination of X-line and CT showed that the height of intervertebral lost rate was 18% (4/22) and the lumbar interbody fusion rate is 86% (19/22). There was no complication, such as infection, hematoma, nerve injury, B-twin falling off. Conclusion Application of posterior endoscopic discectomy combined with B-Twin lumbar interbody fusion in the treatment of lumbar intervertebral disc protrusion with degenerative lumbar spinal instability has little trauma and bleeding, and the recent follow-up results are satisfactory.%目的 探讨后路内窥镜下髓核摘除术联合可膨胀脊柱融合器(B-Twin)椎间融合治疗腰椎退变失稳性椎间盘突出症的疗效.方法 选择2007年11月~2009年11月我院收治的退行性腰椎间盘突出症合并腰椎失稳患者22例,均采用后路内窥镜下髓核摘除

  20. Clinical outcome of anterior cervical corpectomy with fusion versus anterior cervical discectomy with fusion for multilevel cervical spondylosis%椎体次全切除与椎间隙减压治疗多节段颈椎病的疗效比较

    Institute of Scientific and Technical Information of China (English)

    宋科冉; 袁文; 王新伟; 张颖

    2011-01-01

    Objective To compare the clinical effect and radiological results between anterior cervical corpectomy with fusion (ACCF) and anterior cervical discectomy with fusion (ACDF) in the treatment of nulttilevel cervical spondylosis.Methods A total of 118 patients with multilevel cervical spondylosis who underwent ACCF or ACDF from June 2002 to June 2007 were analyzed respectively. And the patients were divided into Group A (2-level treated with ACCF, n = 33), Group B (2-level treated with ACDF,n =30), Group C (3-level treated with ACCF, n=28), Group D (3-level treated with ACDF,n=27) The clinical outcomes were compared between Group A and Group B, and also between Group C and Group D.Results Compared with Group B, Group A had shorter operation time and a higher postoperative 3 months fusion rate, and the differences were statistically significant ( P <0. 05 ). Compared with Group D, Group C had more blood loss in operation lower fusion rate and lower increased height of fusion segment of postoperative 3 months, and the differences were statistically significant ( P <0. 05 ); but the postoperative curvature of fusion segment of Group C was better than that of Group D and the differences were statistically significant ( P < 0. 05). Tne differences of other datas between Group A and Group B or Group C and Group D were not statistially significant ( P > 0. 05 ). Conclusion For patients with 2-level cervical spondylosis, ACCF and ACDF are both effective operation types; but the ACCF has a better field of vision than ACDF. For patients with 3-level cervical spondylosis, both operation types can be used; and the postoperative curvature of fusion segment of ACDF was worse than ACCF, but cage subsidence maybe occur after ACCF.%目的 比较椎体次全切除减压植骨融合术(anterior cervical corpectomy with fusion,ACCF)和经椎间隙减压植骨融合术(anterior cervical discectomy with fusion,ACDF)治疗多节段颈椎病的临床疗效及影像学结果.方法

  1. 单节段双节段颈椎融合术后颈椎活动度的观察%Motion changes of cervical range after one or two-level cervical spine fusion

    Institute of Scientific and Technical Information of China (English)

    赵信; 徐宏光; 郑权; 方振; 赵泉来; 王弘; 刘平

    2015-01-01

    目的:探讨单节段及双节段颈椎融合手术对颈椎活动度的影响。方法:选取2010年6月~2012年6月在皖南医学院附属弋矶山医院脊柱外科行颈椎前路减压融合术的43例颈椎病患者,其中单节段融合29例,双节段融合14例。根据症状及X线片评价手术的有效率及融合节段的融合率。使用颈椎活动度测量仪( cervical range of motion device ,CROM)测量患者术前及术后随访24个月时颈椎前屈、后伸、左右侧弯、左右旋转6个方向的活动度。结果:从患者主诉分析,所有患者临床症状均得到缓解,通过X线评价融合节段融合率为100%。与术前相比单节段融合术后患者颈椎左右侧弯方向活动度无明显差异(P>0.05),而在前屈、后伸及左右旋转方向的活动度均较术前明显减低(P<0.05)。行双节段融合手术后患者颈椎在6个方向的活动度较术前均明显减低( P<0.05)。对两种不同融合术后患者颈椎活动度的差异进行统计学分析后发现双节段融合患者术后颈椎活动度在6个方向均较单节段融合患者降低( P<0.05)。结论:颈椎融合手术能够降低患者颈椎的活动度,与单节段融合相比双节段融合术后颈椎活动度的降低更为明显。%Objective:To observe the impact of one or two-level and double-level cervical spine fusion on the rang of cervical motion .Methods:Forty-three patients undergone cervical spine fusion in our department between June of 2010 and 2012 were included,among whom 29 received single-level fusion,and 14,two-level fusion.The curative effects and fusion rate of spine were evaluated by presented symptoms and X-ray findings.The cervical flexion,backward extension,left and right lateral bending,left and right rotation of the cervical vertebrae were measured by the cervical range of motion device(CROM) in all patients before operation and post-operative 24-month follow

  2. Clinical Application Of Locking Cervical lntervertebral Fusion Cage In Unisegmental Intervertebral Disk Hernia Of Cervical Vertebrae%锁定式颈椎融合器治疗单节段颈椎问盘突出症

    Institute of Scientific and Technical Information of China (English)

    范磊; 何斌; 邵增务; 王云华

    2011-01-01

    目的 探讨应用颈椎前路减压结合锁定式颈椎融合器治疗单节段颈椎间盘突出症的临床疗效.方法 21例单节段颈椎间盘突出症应用颈椎前路减压加锁定式颈椎融合器植骨融合术治疗,并对其疗效进行评价.结果 所有病例随访12~24个月,平均17.6个月.6个月后椎体间均达到骨性融合,无并发症出现,脊髓功能状态评分术后1个月及术后6个月优良率分别达66.67%、85.71%.结论 应用颈椎前路减压结合锁定式颈椎融合器治疗单节段颈椎间盘突出症疗效肯定.%Objective To evaluate the clinic curative effect of anterior cervical decompression and implantation of cervical intervertebral fusion cage in the treatment of unisegmental intervertebral disk hernia of cervical vertebrae. Methods 21 cases of unisegmental intervertebral disk hernia of cervical vertebrae were treated with anterior cervical decompression and implantation of locking cervical Intervertebral fusion cage and the curative effect was evaluated. Results All cases were followed up for 12~24 months (17. 6 months in average). All patients gained osseous fusion 6 monthes after the operation and there was no complication. According to the functional status score of spinal cord. The fineness rate was 66. 67% 1 month after the operation and 85. 71% 6 monthes after the operation. Conclusion The curative effect of the treatment of unisegmental intervertebral disk hernia of cervical vertebrae anterior cervical decompression and implantation of locking cervical Intervertebral fusion cage was affirmative.

  3. The relationship between discography pressure and outcome of anterior lumbar interbody fusion for discogenic low back pain%椎间盘造影压力与椎间盘源性腰痛手术疗效的关系

    Institute of Scientific and Technical Information of China (English)

    张继东; 夏群; 胡永成; 苗军; 徐宝山

    2009-01-01

    目的 探讨椎间蕊造影压力与腰椎间盘源件疼痛手术疗效的关系.方法 2004年4月至2006年6月,65例慢性腰痛患者经压力控制性椎间盘造影确诊为椎间盘源性腰痛.其中22例经保守治疗无效者接受前路腰椎椎间融合术,年龄25~67岁,平均43.6岁.L4-5例,L5S112例,L4-5和L5S1双间隙2例.记录椎间盘造影诱发疼痛时的压力,将患者分为椎间盘造影压力≤300 kPa(低压组)10例,300~500 kPa(高压组)12例.椎间cage融合术22例24个椎间盘.术后3~7 d下地活动.腰围固定3个月.根据术前、术后VAS评分和ODI评分比较高压组和低压组手术疗效.结果 所有患者随访6~26个月,平均18个月.手术时间70~120 min,平均90 min;出血量100~400 ml,平均220 ml.低压组与高压组术前VAS评分和ODI评分、椎间隙高度、手术时间、出血量差异无统计学意义.术后腰及下肢痛症状明显缓解,均恢复正常生活或工作.椎间隙高度从术前平均9.5 mm增加至13.5 mm.术后6个月低压组VAS、ODI改善率分别为82.4%、90.1%,高压组为71.7%、80.6%.随访时未发现肠梗阻、逆行射精和假体位置移动.结论 压力控制性椎间盘造影能够提高椎间盘源性腰痛的诊断准确性,低压力椎间盘造影阳性者手术疗效更好.%Objective To explore the relationship between discography pressure and outcome of an-terior lumbar interbody fusion (ALIF) for discogenic low back pain. Methods From April 2004 to June 2006, 65 patients with chronic low back pain were identified as diseogenic origin by pressure controlled discography, 22 cases of which received ALIF after failed conservative treatment for at least 6 months. The surgically treated patients aged 43.6 on the average (range, 25-67). The treated discs located: 8 in L4-5, 12 in L5S1, 2 in both L4-5 and L5S1. 22 cases received ALIF in 24 levels via retroperitoneal approach. The pressure as soon as accordant initially induced pain was recorded during

  4. 经椎间孔椎间融合后腰椎即刻稳定性的生物力学实验%Initial lumbar stability following transforaminal interbody fusion: Biomechanical test

    Institute of Scientific and Technical Information of China (English)

    陈兵乾; 张烽; 董士奎; 居建文; 王素春; 王以进

    2008-01-01

    背景:经椎间孔椎间融合适用于腰椎任何节段,并且保留了侧椎板和关节突关节的完整,较传统的椎间融合具有一定的优势,但有关其生物力学性能的研究很少.目的:应用生物力学应力方法观察经椎间孔椎间融合术后及附加单侧和双侧椎弓根螺钉后腰椎即刻稳定性的变化.设计、时间及地点:生物力学测试,于2005-08/2006-04在南通大学和上海大学生物力学研究所完成.材料:新鲜1月龄小牛腰椎标本20具.方法:20具小牛标奉模拟临床手术,分别依次建市经椎间孔椎间融合单纯椎间融合模型、经椎间孔椎间融合附加单侧椎弓根螺钉模型、经椎间孔椎间融合附加双侧椎弓根螺钉模型,每组5个标本,在脊柱三维运动测试机上进行生物力学测试.主要观察指标:记录应变、位移、应力、扭角等力学量.结果:行单纯经椎间孔椎间融合后,虽然在平均应变和应力上变化不大,但刚度和扭转强度明显减小了,说明虽然椎间融合器的植入能提供即刻的稳定性.分别附加单侧椎弓根螺钉和双侧椎弓根螺钉固定后,其稳定性明显比单纯融合组加强了,甚至超过正常组,附加双侧内固定组的稳定性明显优于单侧内固定组.虽然附加单侧椎弓根螺钉同定后的腰椎稳定性逊于附加双侧椎弓根螺钉固定组,但是其即刻稳定性也大大地加强了,甚至超过了正常标本,说明附加单侧内固定同样也能提供腰椎术后足够的初始稳定性.结论:单纯经椎间孔椎间融合后,腰椎的初始稳定性是不够的,附加单侧和双侧椎弓根螺钉固定都能明显的增加腰椎的初始稳定性.%BACKGROUND:Transforaminal lumbar interbody fusion(TLIF)can be applied in any lumbar segment,and retain integrity of lateral vertebral plate and zygapophysiai joints.However,few studies have been conducted about the biomechanical performance.OBJECTIVE:To explore the stability of lumbar

  5. Biomechanische Untersuchung eines biodegradierbaren Cages zur interkorporellen Spondylodese der Halswirbelsäule.

    OpenAIRE

    Gumnior, Sarah Nicole Stephanie

    2010-01-01

    Biomechanical evaluation of a biodegradable cage for interbody fusion at the cervical spine Biomechanical evaluation of a biodegradable cage for interbody fusion in the cervical spine. A in vivo animal study in a sheep model.   Abstract Background Anterior interbody fusion using an intervertebral spacer is a widely accepted surgical treatment for patients with degenerative and traumatic cervical spinal-c...

  6. Cervical disc herniation presenting with neck pain and contralateral symptoms: a case report

    Directory of Open Access Journals (Sweden)

    Yeung Jacky T

    2012-06-01

    Full Text Available Abstract Introduction Cervical disc herniation often results in neck and arm pain in patients as a result of direct impingement of nerve roots and associated inflammatory processes. The clinical presentation usually corresponds with the side of herniation and ipsilateral symptoms predominate the clinical picture. Case presentation A 35-year-old Caucasian man presented to our facility with neck pain and left-sided upper and lower extremity pain. A magnetic resonance imaging scan revealed a right paramedian herniated disc at the C5 to C6 level. All other cervical levels were normal without central canal stenosis or neural foraminal stenosis. Results from magnetic reasonance imaging scans of the brain and lumbar spine were negative. An anterior cervical discectomy was performed at the C5 to C6 level, and an inter-body graft and plate were placed. Our patient had complete resolution of his neck and left arm pain. Conclusions Anterior discectomy and fusion of the cervical spine resulted in complete resolution of our patient’s neck and left arm symptoms and improvement of his contralateral left leg pain. Cervical disc herniation may present with contralateral symptoms that are different from the current perception of this disease.

  7. Influence of interbody fusion intervertebral fixation on adjacent joint degeneration in patients with lumbar diseases%椎间植骨融合内固定术对腰椎疾患邻近椎间关节退变的影响

    Institute of Scientific and Technical Information of China (English)

    黄占柱; 仇小华; 张淑兰; 陈为国; 郭颖

    2014-01-01

    Objective To explore the influence of interbody fusion intervertebral fixation on adjacent joint degeneration in patients with lumbar diseases .Methods 56 patients with lumbar diseases who were taken interbody fusion intervertebral fixation were selected as the research subjects ,and the adjacent intervertebral joint degeneration in patients were followed up .Results 56 patients were followed up for 24-72 months,the average time was (41.2 ± 8.3)months.The new clinical symptoms were occurred in 12 cases(21.4%),including 8 cases of low back pain, 3 patients with leg pain,1 case of lumbocrural pain.Radiographic changes occurred in 9 cases(16.1%),9 cases of patients with new clinical symptoms ,including 5 cases of osteophyte formation or exacerbation ,2 cases for adjacent segment instability ( I degree of vertebral spondylolisthesis ) ,1 case of small joint hyperplasia stage spinal stenosis , 1 case of protrusion of intervertebral disc .In 9 patients with imaging performance ,internal fixation of upper adjacent segment degeneration in 7 cases,internal fixation of the adjacent segment degeneration in 2 cases.Conclusion Inter-body fusion intervertebral fixation in the treatment of lumbar diseases ,adjacent joint is prone to degeneration ,so the destruction of adjacent joint operation should be reduced .%目的:探讨椎间植骨融合内固定术对腰椎疾患邻近椎间关节退变的影响。方法以采用椎间植骨融合内固定术治疗的腰椎疾患患者56例作为研究对象,随访患者术后邻近椎间关节的退变情况。结果56例患者均获门诊随访,随访时间24~72个月,平均(41.2±8.3)个月。其中出现新的临床症状有12例(21.4%),其中8例为下腰痛、3例为下肢痛、1例为腰腿痛;出现影像学改变9例(16.1%),9例患者均伴有新的临床症状,其中5例为骨赘形成或加重,2例为邻近节段不稳(椎体I度滑脱),1例为小关节增生

  8. 钉棒置入与椎间融合修复极外侧型腰椎间盘突出症:远期腰椎稳定性随访%Extreme lateral lumbar disc herniation after pedicle screw fixation and interbody fusion cage:lumbar stability at long-tem follow-up

    Institute of Scientific and Technical Information of China (English)

    史瑞明; 李国胜; 张义峰; 黄震源; 孙利; 王存

    2014-01-01

    BACKGROUND:Extreme lateral lumbar disc herniation is a rare type of lumbar disc herniation, there are a variety of treatment methods, but the therapeutic efficacy and recurrence rate are controversial. OBJECTIVE:To investigate the availability of lumbar pedicle screw fixation combined with interbody fusion cage for treating extreme lateral lumbar disc herniation. METHODWe retrospectively analyzed 19 patients with extreme lateral lumbar disc herniation after treatment with lumbar pedicle screw fixation combining with interbody fusion cage from March 2006 to January 2009. The outcomes were evaluated depending on VAS scoring standard and Macnab scoring standard, lumbar stability were observed postoperatively. We analyzed the spinal stability in recurrent lumbar disc herniation patients after lumbar pedicle screw fixation combined with interbody fusion cage depending on literature search. RESULTS AND CONCLUSION:Al the 19 patients were fol owed up for 13 months to 3 years, the leg and lumbar pain of al the patients were relieved to varying degrees. Preoperative VAS score was 7.3±1.28 points and postoperative VAS score was 2.1±0.8 points, showing significant difference between two groups (P  目的:探讨应用腰椎椎弓根钉棒内固定联合椎间融合器置入椎间融合修复极外侧型腰椎间盘突出症的临床效果。  方法:回顾性分析2006年3月至2009年1月行腰椎椎弓根钉棒系统联合椎间融合器置入椎间融合治疗的19例极外侧型腰椎间盘突出症患者的临床资料,根据目测类比评分标准及Macnab评价标准进行疗效判定,观察治疗后腰椎稳定性,通过数据库文献检索方法评估腰椎椎弓根钉棒内固定联合椎间融合器置入椎间融合修复极外侧型腰椎间盘突出症的效果。  结果与结论:19例患者均得到随访,随访时间13个月-3年。所有患者治疗后即有下肢及腰部疼痛不同程度的缓解,治

  9. 不同融合节段后路减压椎间融合内固定术对邻近节段稳定性影响的影像学分析%Radiologic stability analysis of adjacent segments after different fusion segments of posterior lumbar interbody fusion

    Institute of Scientific and Technical Information of China (English)

    刘玉增; 海涌; 杨晋才; 关立

    2013-01-01

    Objective To investigate the radiologic stability of adjacent segments after single, double and triple fusion segments of posterior lumbar interbody fusion ( PLIF ). Methods All 45 patients who were treated by PLIF were divided into 3 groups, including group A of single segment, group B of double segments and group C of triple segments, with 15 patients in each group. The effects on the stability of adjacent segments after fusion were retrospectively analyzed. The preoperative and postoperative lumbar lordosis angle and range of motion ( ROM ) of upper adjacent segments were measured. Results The results showed the lumbar ROM was decreased in the latest follow-up when compared with that preoperatively by 10.4° in group A, 11.4° in group B and 16° in group C on average. And the ROM of adjacent segments was increased in the latest follow-up when compared that preoperatively by 2.1° in group A, 1.9° in group B and 8.1° in group C on average. The preoperative ROM of adjacent segments was ( 3.6±2.0 ) °, ( 8.4±5.5 ) ° and ( 5.0±4.5 ) ° in group A, group B and group C, and the postoperative ROM was ( 6.5±1.6 ) °, ( 9.8±9.5 ) ° and ( 13.0±7.6 ) ° respectively. The differences between the preoperative and postoperative ROM in each group were statistically signiifcant ( P<0.01 ), and the differences of the postoperative ROM among all groups were statistically signiifcant ( P<0.01 ). Conclusions With the adding of fusion segments, the ROM of adjacent segments also increases. Based on the preoperative lumbar lordosis angle, a modest recovery of the physiological lordosis angle is achieved during the operation. It is an effective method to maintain the stability of adjacent segments.%目的探讨单节段、双节段和三节段后路椎间融合器置入椎弓根内固定术( posterior lumbar interbody fusion,PLIF )对融合节段邻近节段稳定性的影响。方法回顾性单节段( A组),双节段( B组)和三节段( C组) PLIF,共45例,对融

  10. An Outcome Study of Anterior Cervical Discectomy and Fusion among Iranian Population.

    Science.gov (United States)

    Haghnegahdar, Ali; Sedighi, Mahsa

    2016-01-01

    Background and Aim. First-line treatment strategy for managing cervical disc herniation is conservative measures. In some cases, surgery is indicated either due to signs/symptoms of severe/progressive neurological deficits, or because of persistence of radicular pain despite 12 weeks of conservative treatment. Success for treatment of cervical disc herniation using ACDF has been successfully reported in the literature. We aim to determine the outcome of ACDF in treatment of cervical disc herniation among Iranians. Methods and Materials/Patients. In a retrospective cohort study, we evaluated 68 patients who had undergone ACDF for cervical disc herniation from March 2006 to March 2011. Outcome tools were as follows: (1) study-designed questionnaire that addressed residual and/or new complaints and subjective satisfaction with the operation; (2) recent (one week prior to the interview) postoperative VAS for neck and upper extremity radicular pain; (3) Japanese Orthopaedic Association Myelopathy Evaluation Questionnaire (JOACMEQ) (standard Persian version); and (4) follow-up cervical Magnetic Resonance Imaging (MRI) and lateral X-ray. Results. With mean follow-up time of 52.93 (months) ± 31.89 SD (range: 13-131 months), we had success rates with regard to ΔVAS for neck and radicular pain of 88.2% and 89.7%, respectively. Except QOL functional score of JOAMEQ, 100% success rate for the other 4 functional scores of JOAMEQ was achieved. Conclusion. ACDF is a successful surgical technique for the management of cervical disc herniation among Iranian population. PMID:27635392

  11. An Outcome Study of Anterior Cervical Discectomy and Fusion among Iranian Population

    Directory of Open Access Journals (Sweden)

    Ali Haghnegahdar

    2016-01-01

    Full Text Available Background and Aim. First-line treatment strategy for managing cervical disc herniation is conservative measures. In some cases, surgery is indicated either due to signs/symptoms of severe/progressive neurological deficits, or because of persistence of radicular pain despite 12 weeks of conservative treatment. Success for treatment of cervical disc herniation using ACDF has been successfully reported in the literature. We aim to determine the outcome of ACDF in treatment of cervical disc herniation among Iranians. Methods and Materials/Patients. In a retrospective cohort study, we evaluated 68 patients who had undergone ACDF for cervical disc herniation from March 2006 to March 2011. Outcome tools were as follows: (1 study-designed questionnaire that addressed residual and/or new complaints and subjective satisfaction with the operation; (2 recent (one week prior to the interview postoperative VAS for neck and upper extremity radicular pain; (3 Japanese Orthopaedic Association Myelopathy Evaluation Questionnaire (JOACMEQ (standard Persian version; and (4 follow-up cervical Magnetic Resonance Imaging (MRI and lateral X-ray. Results. With mean follow-up time of 52.93 (months ± 31.89 SD (range: 13–131 months, we had success rates with regard to ΔVAS for neck and radicular pain of 88.2% and 89.7%, respectively. Except QOL functional score of JOAMEQ, 100% success rate for the other 4 functional scores of JOAMEQ was achieved. Conclusion. ACDF is a successful surgical technique for the management of cervical disc herniation among Iranian population.

  12. An Outcome Study of Anterior Cervical Discectomy and Fusion among Iranian Population

    Science.gov (United States)

    Haghnegahdar, Ali

    2016-01-01

    Background and Aim. First-line treatment strategy for managing cervical disc herniation is conservative measures. In some cases, surgery is indicated either due to signs/symptoms of severe/progressive neurological deficits, or because of persistence of radicular pain despite 12 weeks of conservative treatment. Success for treatment of cervical disc herniation using ACDF has been successfully reported in the literature. We aim to determine the outcome of ACDF in treatment of cervical disc herniation among Iranians. Methods and Materials/Patients. In a retrospective cohort study, we evaluated 68 patients who had undergone ACDF for cervical disc herniation from March 2006 to March 2011. Outcome tools were as follows: (1) study-designed questionnaire that addressed residual and/or new complaints and subjective satisfaction with the operation; (2) recent (one week prior to the interview) postoperative VAS for neck and upper extremity radicular pain; (3) Japanese Orthopaedic Association Myelopathy Evaluation Questionnaire (JOACMEQ) (standard Persian version); and (4) follow-up cervical Magnetic Resonance Imaging (MRI) and lateral X-ray. Results. With mean follow-up time of 52.93 (months) ± 31.89 SD (range: 13–131 months), we had success rates with regard to ΔVAS for neck and radicular pain of 88.2% and 89.7%, respectively. Except QOL functional score of JOAMEQ, 100% success rate for the other 4 functional scores of JOAMEQ was achieved. Conclusion. ACDF is a successful surgical technique for the management of cervical disc herniation among Iranian population. PMID:27635392

  13. 360° fusion for realignment of high grade cervical kyphosis by one step surgery: Case report.

    Science.gov (United States)

    Landi, Alessandro; Marotta, Nicola; Mancarella, Cristina; Dugoni, Demo Eugenio; Tarantino, Roberto; Delfini, Roberto

    2014-07-16

    Surgical treatment for cervical kyphotic deformity is still controversial. Circumferential approach has been well described in the literature but long terms outcomes are not well reported. Important to decide the correct treatment option is the preoperative radiological exams to value the type of deformity (flexible or fixed). We report the case of a 67-year-old woman affected by a severe cervical kyphotic deformity who underwent combined anterior/posterior surgical approach, getting a good reduction of the deformity and an optimal stability in a long term follow up.

  14. 后路椎间融合加椎弓根螺钉固定术治疗退行性腰椎间盘病变%Posterior lumbar interbody fusion combined with pedicle screw fixation in treatment of degenerative diseases of lumbar intervertebral disc

    Institute of Scientific and Technical Information of China (English)

    黄占柱; 仇小华; 张如意

    2011-01-01

    Objective To investigate the clinical effect of treating the patients suffering from degenerative diseases of lumbar intervertebral disc with posterior lumbar interbody fusion (PLIF) combined with pedicle screw fixation.Methods This study was based on 100 cases suffering from degenerative diseases of lumbar intervertebral disc who underwent PLIF combined with pedicle screw fixation.All the patients were followed by 1 - 2 years.The shape and the function of spinal column were both estimated before and after the operation,and they were also estimated during the following of the patients after the operation.The datas in the formal 3 stages were multiply compared.Results Between the preoperative and postoperative datas,there were statistically significant differences in the JOA scores and the angle of scoliosis and kyphosis (P < 0.05 ).And so do the preoperative datas and the datas during the following (P <0.05).But no similar result was detected between the postoperative data and the data during the following (P > 0.05).Conclusions Posterior lumbar interbody fusion (PLIF) combined with pedicle screw fixation has a significant effect in treating degenerative diseases of lumbar intervertebral disc,deserving further study and clinical popularization.%目的 探讨后路椎间融合加椎弓根螺钉固定术治疗退行性腰椎间盘病变的临床疗效.方法 对100例退行性腰椎间盘病变患者采取后路椎间融合加椎弓根螺钉固定术,术后予1~2年随访,并比较术前、术后及随访时脊柱形态、功能恢复情况(JOA评分).结果 术后与术前患者脊柱后凸、侧凸角度和JOA评分比较差异均有统计学意义(P均<0.05),随访时与术前比较差异也有统计学意义(P<0.05),随访时与术后比较差异无统计学意义(P>0.05).结论 后路椎体间融合术治疗退行性腰椎间盘病变效果显著,有进一步研究和推广价值.

  15. L4、5侧路单枚cage椎间融合术式的生物力学及临床研究%Biomechanical and Clinical Study of L4.5 Lateral Lumbar Interbody Fusion Using Single Anatomical Threaded Cage

    Institute of Scientific and Technical Information of China (English)

    郑忠; 翁绳健; 吴立忠; 李炜明; 陈国龄

    2011-01-01

    Objective To evaluate the relative stability of L4.5 lateral lumbar interbodyfusion using single anatomical threaded cage.Methods Twelve calf spine models and dimensional element models of lateral and posterior approach were established.Pure moment and forces were applied to the top of spinal eolumn. The motion range of all the specimens was measured during the experiment. The improvement rate of lumbar pain in 33 patients who took operation from Dec. 2003 to Dec. 2006 was evaluated. Results The stability in lateral group was superior to posterior group. The effective rate of operation was 100%. The improvement rate of lumbar pain was 93.94%.The patients's satisfactory rate was 100%.Conclusion Interbody fusion of L4.5 through lateral approach using single anatomical threaded cage without internal fixation is a mini-invasive operation process. It can provide instant posterior biomechanical stiffness. It is an effective operation process of interbody fusion in lumbar.%目的 评价L4、5侧路单枚椎间融合器融合术式的稳定性及力学合理性.方法 建立L4、5侧路与后路单枚椎间融合器融合术式的三维有限元模型及小牛脊柱模型,测定二者的位移变化.临床随访2003年12月~2006年12月行侧路单枚椎间融合器融合术式33例,评价腰痛改善率.结果 实验显示侧路模型的稳定性优于后路模型.临床研究显示手术有效率100%,腰痛改善率93.94%,患者满意率100%.结论 侧路植入单枚椎间融合器融合术式是一种微创的术式,不使用椎弓根固定系统而又能够提供足够的术后即刻生物力学刚度,是一种合理有效的腰椎椎间融合术式.

  16. Combination therapy of transforaminal lumbar interbody fusion and Wiltse pedicle screw fixation approach in the treatment of the lumbar disc protrusion%经椎间孔椎间融合术联合Wiltse入路椎弓根固定治疗腰椎间盘突出症

    Institute of Scientific and Technical Information of China (English)

    隋海涛; 冯涛; 李亮; 于学忠

    2013-01-01

    [Objective] To compare the clinical effects of transforaminal lumbar interbody fusion with Wiltse pedicle screw fixation approach combined (TLIF,group A) and posterior lumbar interbody fusion (PLIF,group B).[Methods] From March 2008 to September 2012,186 patients on treatment for lumbar disc were divided into two groups:there were 104 patients in group A,48 males and 56 females,aged between 43 to 65,55 on average and 82 patients in group B,39 males and 43 females,aged between 45 to 67,57 on average.The bleeding volume,average time of operation,the rate of complications,fusion rate,the intervertebral space and the improvements in symptoms were compared and statistical analyzed.Visual analogue pain score (VAS) of low back pain and leg pain as well as the Oswestry disability index (ODI) were used in preoperative assessment and postoperative follow-up for symptoms evaluation.[Results] There were no statistical differences in the age,sex,intervertebral space,VAS score and ODI score before operation.The follow-up times without statistical difference were 26 months on average in group A and 23 months in group B.No significant differences were found between the two groups in last VAS scores of leg pain,ODI scores,fusion rate and intervertebral space (P > O.05).But group A had significant (P < 0.01) advantages of the bleeding volume,average time of operation,the rate of complications and the last VAS scores of low back pain.Significant improvements (P < 0.01) of intervertebral space,VAS scores and ODI scores after operation were ensured in both groups by the last follow-ups.[Conclusion] The efficacy of TLIF and PLIF are both satisfactory,but TLIF is better for less trauma,fewer complications and lower residual low back pain rate after operation.%[目的]比较经椎间孔腰椎椎间融合术(transforaminal lumbar interbody fusion,TLIF,A组)联合Wiltse入路椎弓根固定与传统经后路腰椎椎间融合术(posterior lumbar interbody fusion,PLIF,B组)治疗腰

  17. Avaliação clínica radiológica da artrodese lombar transforaminal aberta versus minimamente invasiva Evaluación clínica radiológica de la artrodesis lumbar transforaminal abierta versus mínimamente invasiva Clinical and radiological evaluation of open transforaminal lumbar interbody fusion versus minimally invasive

    Directory of Open Access Journals (Sweden)

    Cristiano Magalhães Menezes

    2009-09-01

    Full Text Available OBJETIVO: a proposta deste trabalho é comparar os resultados clínicos e radiológicos dos pacientes submetidos à artrodese transforaminal aberta e minimamente invasiva. MÉTODOS: quarenta e cinco pacientes foram submetidos à artrodese lombar transforaminal pelo Grupo de Cirurgia Espinhal do Hospital Lifecenter/Ortopédico de Belo Horizonte, no período de Dezembro de 2005 a Maio de 2007, sendo 15 no grupo de artrodese aberta e 30 pacientes do grupo de artrodese minimamente invasiva (MIS. As indicações para a artrodese intersomática foram: doença degenerativa do disco, associada ou não a hérnia de disco ou estenose do canal; espondilolistese de baixo grau espondilolítica ou degenerativa; e síndrome pós-laminectomia/discectomia. As variáveis analisadas foram: tempo de cirurgia, tempo de internação hospitalar, necessidade de hemotransfusão, escala analógica visual de dor (VAS lombar e dos membros inferiores, Oswestry, índice de consolidação da artrodese e retorno ao trabalho. RESULTADOS: o seguimento mínimo foi de 24 meses. Havia oito homens e sete mulheres no Grupo Aberto e 17 homens e 13 mulheres no Grupo MIS. O tempo cirúrgico médio foi de 222 minutos e 221 minutos, respectivamente. Houve melhora significativa da VAS e Oswestry no pós-operatório em ambos os grupos. O tempo de internação hospitalar variou de 3,3 dias para o Grupo Aberto e 1,8 dias para o Grupo MIS. O índice de fusão obtido foi de 93,3% em ambos os grupos. Houve necessidade de hemotransfusão em três pacientes no Grupo Aberto (20% e nenhum caso MIS. CONCLUSÕES: a transforaminal lumbar interbody fusion (TLIF minimamente invasiva apresenta resultados similares em longo prazo quando comparado à TLIF aberta, com os benefícios adicionais de menor morbidade pós-operatória, menor período de internação e reabilitação precoce.OBJETIVO: la propuesta de este trabajo es comparar los resultados clínicos y radiológicos de los pacientes sometidos a la

  18. 腰椎退行性变的经皮椎弓根螺钉固定结合微创腰椎间融合术治疗%Percutaneous pedicle screw ifxation combined with minimally invasive lumbar interbody fusion in the treatment of lumbar degenerative disease

    Institute of Scientific and Technical Information of China (English)

    何二兴; 郭倞; 崔基浩; 郭志勇; 尹知训; 李创; 唐程; 何贻骞; 刘成伟

    2015-01-01

    Objective To investigate the safety and effectiveness of percutaneous pedicle screw fixation combined with minimally invasive lumbar interbody fusion in the treatment of lumbar degenerative disease.Methods From November 2012 to August 2014, a total of 127 patients with lumbar degeneration and instability were recruited. There were 86 males and 41 females, with the mean age of 58.4 years ( range: 18-79 years ). There were 16 cases of spondylolisthesis, 35 cases of lumbar disc herniation, and 76 cases of lumbar stenosis. According to different pathological characteristics, percutaneous pedicle screw ifxation combined with minimally invasive posterior lumbar interbody fusion ( mini-plif ) (44 cases), minimally invasive transforaminal lumbar interbody fusion ( mini-tlif ) ( 49 cases ) or extended decompression and fusion ( 34 cases ) were performed respectively for treatment. The postoperative followed-up was at least 3 months. Before surgery, all patients received anteroposterior, lateral and lfexion-extension X-ray examination of the lumbar spine, as well as lumbar MRI. The average insertion time and X-ray exposure times for each pedicle screw, average blood loss and postoperative drainage volume for each decompression level were analyzed. Hospital stay, pedicle screw position and complications were also recorded. Pre- and postoperative 3-days, 2-weeks, 3-months visual analogue scale ( VAS ) and Oswestry disability index ( ODI ) scores were compared. Results The average insertion time for each pedicle screw was ( 12.6±6.3 ) min. The average X-ray exposure times for each pedicle screw was ( 4.2±2.3 ) times. The mean blood loss for each decompression level was ( 67.9±16.7 ) ml,and the postoperative drainage volume was ( 52.6±13.8 ) ml. The average hospital stay was ( 9.0±2.4 ) days. The VAS and ODI scores were found to be signiifcantly improved after surgery in 3 groups (P<0.05 ). A total of 635 screws were inserted. The position of pedicle screws was good in 546

  19. Cervical radiculopathy.

    Science.gov (United States)

    Iyer, Sravisht; Kim, Han Jo

    2016-09-01

    Cervical radiculopathy is a common clinical scenario. Patients with radiculopathy typically present with neck pain, arm pain, or both. We review the epidemiology of cervical radiculopathy and discuss the diagnosis of this condition. This includes an overview of the pertinent findings on the patient history and physical examination. We also discuss relevant clinical syndromes that must be considered in the differential diagnosis including peripheral nerve entrapment syndromes and shoulder pathology. The natural history of cervical radiculopathy is reviewed and options for management are discussed. These options include conservative management, non-operative modalities such as physical therapy, steroid injections, and operative intervention. While the exact indications for surgical intervention have not yet been elucidated, we provide an overview of the available literature regarding indications and discuss the timing of intervention. The surgical outcomes of anterior cervical decompression and fusion (ACDF), cervical disc arthroplasty (CDA), and posterior cervical foraminotomy (PCF) are discussed. PMID:27250042

  20. ACDR 和 ACDF 治疗单节段颈椎间盘突出症的对比分析%Comparative analysis of ACDR and ACDF in the treatment of single segmental cervical intervertebral disc herniation

    Institute of Scientific and Technical Information of China (English)

    黄长安; 李军; 袁文旗; 周立

    2015-01-01

    目的:对比分析颈椎前路椎间盘切除植骨融合术( ACDF)和颈椎人工椎间盘置换术( ACDR)%Objective To compare the effect of anterior cervical discectomy and interbody fusion(ACDF) and artificial cervical disc replacement(ACDR) in the treatment of single segmental cervical disc herniation.Methods A total of 81 patients with single segmental cervical disc herniation were collected in our hospital from January 2010 to June 2014, in which 40 patients received ACDF surgery(fusion group) and other 41 patients underwent ACDR sur-gery(permutation group).The changes of activity were compared between the two groups before and the last follow-up after the surgery.Results There were significant differences in the changes of activity between the two groups at the last time of follow-up after the surgery(P <0.01).For each group, the activity improved at the end of the follow-up compared with that before the surgery(P <0.01).Conclusion Both ACDR and ACDF are effective in the treatment of single segmental cervical disc herniation, which improves the activity of cervical disc herniation.ACDR also makes the surgery adjacent segments of the compensatory activity increased, and therefore may prevent adjacent segment de-generation.

  1. Multilevel decompressive laminectomy and transpedicular instrumented fusion for cervical spondylotic radiculopathy and myelopathy: A minimum follow-up of 3 years

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    Kadir Kotil

    2011-01-01

    Full Text Available Objective: Cervical laminectomies with transpedicular insertion technique is known to be a biomechanically stronger method in cervical pathologies. However, its frequency of use is low in the routine practice, as the pedicle is thin and risk of neurovascular damage is high. In this study, we emphasize the results of cervical laminectomies with transpedicular fixation using fluoroscopy in degenerative cervical spine disorder. Materials and Methods: Postoperative malposition of the transpedicular screws of the 70 pedicles of the 10 patients we operated due to degenerative stenosis in the cervical region, were investigated. Fixation was performed between C3 and C7, and we used resected lamina bone chips for fusion. Clinical indicators included age, gender, neurologic status, surgical indication, and number of levels stabilized. Dominant vertebral artery of all the patients was evaluated with Doppler ultrasonography. Preoperative and postoperative Nurick grade of each patient was documented. Results: No patients experienced neurovascular injury as a result of pedicle screw placement. Two patients had screw malposition, which did not require reoperation due to minor breaking. Most patients had 32-mm screws placed. Postoperative computed tomography scanning showed no compromise of the foramen transversarium. A total of 70 pedicle screws were placed. Good bony fusion was observed in all patients. At follow-up, 9/10 (90% patients had improved in their Nurick grades. The cases were followed-up for an average of 35.7 months (30-37 months. Conclusions: Use of the cervical pedicular fixation (CPF provides a very strong three-column stabilization but also carries vascular injury without nerve damage. Laminectomies technique may reduce the risk of malposition due to visualization of the spinal canal. CPF can be performed in a one-stage posterior procedure. This technique yielded good fusion rate without complications and can be considered as a good

  2. 生物活性玻璃联合颈椎椎间融合器在颈椎前路椎间融合中的应用%Anterior cervical discectomy and fusion by cervical cage with bioactive glass

    Institute of Scientific and Technical Information of China (English)

    李宏; 李淳德; 邑晓东; 刘洪

    2014-01-01

    BACKGROUND:Bioactive glass has been largely reported to have perfect clinical results in the bone nonunion and fracture healing, but its effect during spinal fusion progress is rarely reported. OBJECTIVE:To explore the safety and effectiveness of anterior cervical discectomy and fusion by cervical cage with bioactive glass METHODS:A total of 68 cases of cervical spondylosis myelopathy were treated with single level anterior cervical discectomy and fusion. Their clinical data were retrospectively analyzed. Al the cases underwent polyetheretherketone cervical cage with autogenous bone (n=32, control group) or bioactive glass (n=32, experimental group). The bone fusion, neurological functional recovery, intervertebral height, change of cervical curve and wound complications in the two groups was recorded and analyzed. RESULTS AND CONCLUSION:Neurological improvement had no difference between the two groups and there was no complication about wound, such as infection and delayed healing. The average rate of bone fusion was 97%in the control group while 94%in the experiment group 3 months after operation which had no significant differences. Six months after operation, al cases gained bone fusion. The intervertebral height and change of cervical curve both maintained wel in the two groups within 3, 6, 12 months after operation which had no significant differences between the two groups. So, anterior cervical discectomy and fusion by cervical cage with bioactive glass is safe and effective.%背景:已有文献报道生物活性玻璃在骨不连、骨折愈合过程中有较佳的临床疗效,但其在脊柱骨融合过程中的效果鲜有报道。  目的:观察生物活性玻璃联合颈椎椎间融合器在颈椎前路椎间融合中应用的安全性和有效性。  方法:回顾性分析68例颈椎前路单节段椎间融合患者资料,全部病例均采用聚醚醚酮材料椎间融合器,其中内填充自体松质骨植骨32

  3. 保留椎体后壁的椎体次全切除术治疗脊髓型颈椎病%Anterior Cervical Corpectomy and Fusion with Preserved Posterior Vertebral Wall for Cervical Spondylotic Myelopathy

    Institute of Scientific and Technical Information of China (English)

    郑军; 申才良; 董福龙; 巩陈; 汪卫兵

    2011-01-01

    Objective:To investigate the effect of anterior cervical corpectomy and fusion with preserved posterior vertebral wall for cervical spondylotic myelopathy (CSM), and to compare the results with preserved posterior vertebral wall with the classical anterior cervical corpectomy with ft,sion. Methods :Forty patients with CSM were randomized into two groups, anterior cervical eorpeetomy with fusion (n = 20) and anterior cervical eorpeetomy and fusion with preserved posterior vertebral wall (n=20). The values of operation time, surgical bleeding, the numbers and types of complications, disc height, segmental lordosis, and fusion tale were compared hetween two groups. Results: The average operation time and surgical hleeding decreased significantly in the anterior cervical corpectomy and fusion with preserved posterior vertebral wall group. Improvements in segmental lordosis and disc height were similar in both groups (P>0.05). Both fusion rates after 2 processes reached 100% at 3 months postoperatively. Conclusion: Anterior cervical corpectomy and fusion with preserved posterior vertebral wall is a feasible procedure for anterior decompression and fusion, with a shorter operation time, less surgical bleeding and smaller structural damage to the cervical vertebrae.%目的:探讨保留椎体后壁椎体次全切除术治疗脊髓型颈椎病的疗效,并与传统的椎体次全切除术比较.方法:脊髓型颈椎病患者40例随机均分为2组,分别行传统的椎体次全切除术和保留椎体后壁的椎体次全切除术.比较2组的手术时间、出血量、并发症、节段高度、节段曲度及植骨融合评分等指标变化.结果:保留椎体后壁组较椎体次全切除术组的手术时间短、出血少.2组节段高度和曲度的改善差异均无统计学意义(P>0.05).2种术式术后3个月植骨融合率均为100%.结论:保留椎体后壁的椎体次全切除术具有手术时间短、出血少、对颈椎椎体结构破坏小等优

  4. Associations between craniofacial morphology, head posture, and cervical vertebral body fusions in men with sleep apnea

    DEFF Research Database (Denmark)

    Svanholt, Palle; Petri, Niels; Wildschiødtz, Gordon;

    2009-01-01

    INTRODUCTION: The aim of this study was to analyze craniofacial profiles and head posture in patients with obstructive sleep apnea (OSA) subgrouped according to cervical column morphology. METHODS: Seventy-four white men aged 27 to 65 years (mean, 49.0 years) diagnosed with OSA in sleep studies...... dimensions between the groups were assessed by unpaired t tests. RESULTS: No significant differences were seen between groups I and III. Between groups I and II, significant differences were seen in jaw relationship (P

  5. Recent therapeutic effects of minimally invasive transforaminal lumbar interbody fusion for single segmental lumbar ;degenerative disease%微创小切口经椎间孔腰椎椎间融合治疗单节段腰椎退变疾病的近期疗效

    Institute of Scientific and Technical Information of China (English)

    岳晨; 李国庆; 张群; 辛欣

    2014-01-01

    Objective To observe the recent therapeutic effects of small incision minimally invasive transforaminal lumbar interbody fusion ( TLIF) on single segmental lumbar degenerative disease .Methods 120 patients with single segmen-tal lumbar degenerative disease were randomly divided into 2 groups, 60 cases in the control group took traditional open trans-foraminal lumbar inter-body fusion treatment , observation group of 60 cases received minimally invasive transforaminal lumbar inter-body fusion treatment , compared 2 groups of patients ’ JOA score and evaluated the life quality of patients with lumbar spine.Results Observation group patients ’ operation time is longer than that of the control group [(149.3 ±23.2) min vs. (128.4 ±24.7) min, P <0.05],but its operation blood loss , length of incision and the average days of hospitalization were significantly lower than that of control group ( P <0.05);2 months after treatment, the observation group patients quality of life score was significantly higher than that in control group [(75.4 ±8.2)points vs.(59.5 ±7.7)points, P <0.05],JOA scores of the 2 groups were all improved ( P <0.05),and the lumbar JOA in observation group after treatment was also higher than that of the control group [(26.6 ±2.8)points vs.(18.5 ±2.4)points, P <0.05].Conclusion Effect of minimally in-vasive small incision transforaminal lumbar interbody fusion for the treatment of single segment lumbar degenerative diseases is good, worthy of clinical choice .%目的:观察微创小切口经椎间孔腰椎椎间融合( TLIF)治疗单节段腰椎退变疾病的近期疗效。方法将收治并确诊的120例单节段腰椎退变疾病患者随机分为2组,对照组60例采取传统开放椎间孔腰椎椎间融合治疗,观察组60例采取微创小切口经椎间孔腰椎椎间融合治疗,比较2组患者在手术住院方面的差异,同时评价患者生活质量、腰椎JOA评分。结果观察组患者

  6. 单侧椎弓根螺钉固定经椎间孔腰椎体间融合治疗腰椎间盘突出症疗效分析%The effect analysis of transforamen lumbar interbody fusion in treatment of lumbar intervertebral disk herniation with unilateral pedicle screw fixation

    Institute of Scientific and Technical Information of China (English)

    李光富; 刘文斌; 罗政; 周焱涛

    2015-01-01

    Objective To explore the effect of transforamen lumbar interbody fusion in treatment of lumbar intervertebral disk herniation with unilateral pedicle screw fixation. Methods Retrospectivly studied the clinical data of 36 patients with lumbar intervertebral disk herniation who were treated through transforamen lumbar interbody fusion with unilateral pedicle screw from January 2011 to October 2012. There were 22 male and 14 female patients, aged form 44 to 68 years old with mean age of 56. The lesion positions included 8 patients in L3/4, 17 patients in L4/5, and 11 patients in L5/S1. The data of operation time, intraoperative bleeding volume, and postoperative drainage volume were collected. Therapeutic effect were evaluated by visual analogue score (VAS), lumbar vertebral score of Japanese Orthopedic Association (JOA) score, and Oswestry dysfunction index (ODI). Results Operation time was 65-100 min with mean time of 85 min. Intraoperative bleeding volume was 100-250 ml with mean volume of 135 ml. Postoperative drainage volume was 100-200 ml with mean volume of 150 ml. Followed up for 12-36 months with mean time of 20 months. No loosening, breakage of screws or displacement of interbody fusion cages were found in the follow up period. The rate of anastomosis was 100%(36/36). The VAS was (7.9 ± 1.2) scores before operation and (1.1±0.3) scores at the end of follow up period, there was significant difference( P<0.05). The JOA score was (10.2±2.6) scores before operation and (23.2±4.3) scores at the end of follow up period, there was significant difference (P<0.05). The ODI was (43.3±6.2) scores before operation and (15.2±4.3) scores at the end of follow up period, there was significant difference ( P<0.05). Conclusion The effect of transforamen lumbar interbody fusion with unilateral pedicle screw fixation is proper for the patients who are suffering from lumbar intervertebral disk herniation, which has advantages of less invasion, less bleeding, better

  7. 显微内镜辅助经皮微创椎间孔入路腰椎椎体间融合术治疗腰椎退行性疾病%Minimally invasive percutaneous transpedicular screw fixation combined with microendoscopy-assisted transforaminal lumbar interbody fusion for lumbar degenerative diseases

    Institute of Scientific and Technical Information of China (English)

    戎利民; 杨阳; 刘斌; 谢沛根; 冯丰; 杨补; 刘小明; 陈瑞强; 何磊; 李宁

    2012-01-01

    背景:传统开放椎间孔入路腰椎椎体问融合术(transforaminal lumbar interbody fusion,TLIF)由于剥离肌肉广泛及长时间牵拉,可导致部分患者持续性腰背痛.随着脊柱微创技术的发展,采用微创手段实施TLIF技术取得了良好的临床效果,但小切口经扩张通道系统的微创TLIF仍不可避免存在肌肉剥离,需探索更加微创的手术方式.目的:探讨显微内镜辅助经皮微刨TLIF治疗腰椎退行性疾病的近期疗效及安全性.方法:2010年9月至2011年7月,72例腰椎退行性疾病患者接受了单节段TLIF手术,腰椎失稳症36例,腰椎管狭窄症25例,复发型腰椎间盘突出症11例.采用VIPER经皮椎弓根螺钉系统结合椎间盘镜下TLIF手术32例(微创组),传统开放TLIF手术40例(开放组),对两组患者近期临床疗效、并发症、术中射线暴露指标等进行比较.结果:所有患者均获随访,随访时间6~15个月,平均9个月.两组手术时间无明显统计学差异(P>0.05),微创组术中出血量、伤口引流量、住院天数、术后应用镇痛药剂量均明显低于开放组(P<0.01);微创组术中射线暴露时间及剂量高于开放组(P<0.01);微创组术后疼痛(VAS评分)及ODI功能指数较开放组明显降低(P<0.01).微创组出现术中减压错误1例,置钉位置错误1例,导针穿透椎体前壁1例,硬膜撕裂1例;开放组出现术中硬膜撕裂3例,术后伤口浅表感染1例.两组患者均未出现神经损伤并发症.结论:显微内镜辅助经皮微创TLIF较传统开放手术具有创伤小、出血少、恢复快、住院时间短等优点,具有良好的近期疗效,是治疗腰椎失稳症值得推荐的微创手术方式.%Background: TLIF (transforaminal lumbar interbody fusion) as traditional open surgery induce persistent low back pain because of wildly separating muscle and long time traction. With recent advances in minimal invasive spine surgery technological development

  8. Minimal invasive transforaminal lumbar interbody fusion versus open transforaminal lumbar interbody fusion

    Directory of Open Access Journals (Sweden)

    Arvind G Kulkarni

    2016-01-01

    Conclusion: The results in MI TLIF are comparable with O-TLIF in terms of outcomes. The advantages of MI-TLIF are lesser blood loss, shorter hospital stay, lesser tissue trauma, and early mobilization. The challenges of MI-TLIF lie in the steep learning curve and significant radiation exposure. The ultimate success of TLIF lies in the execution of the procedure, and in this respect the ability to achieve similar results using a minimally invasive technique makes MI-TLIF an attractive alternative.

  9. 单侧椎弓根螺钉内固定椎间融合治疗腰椎退行性病变临床研究%Unilateral pedicle screw fixation with transforaminal lumbar interbody fusion for the treatment of lumbar degenerative disease

    Institute of Scientific and Technical Information of China (English)

    徐海栋; 陈勇; 许斌; 赵建宁

    2011-01-01

    Objective This study aimed to investigate the clinical outcome of unilateral pedicle screw (Ups) fixation and transforaminal lumbar interbody fusion (TLJF) in the treatment of lumbar degenerative disease. Methods Forty-two patients with lumbar degenerative disease were assigned to two groups on a voluntary basis to receive Ups + TLJF ( n = 24 ) and bilateral pedicle screw fixation combined with fusion between vertebra (n = 18). Pre-and post-operative back pains were compared using the visual analog scale (VAS) system, the clinical outcomes assessed by the Kim method, and the fusion status evaluated by the Schulte method. Results The clinical symptoms of all the patients were improved post-operatively, with no complications. The Ups + TL1F group showed higher VAS and Kim scores than the bilateral fixation group, but no significant differences were observed in the bone graft fusion between the two groups. The patients were followed up for6 to 18 (mean 12.8) months. Conclusion Ups + TLJF, characterized by minimal invasiveness, is a reliable and effective option for the management of lumbar degenerative disease. However, its indications should be well considered.%目的 评估单侧椎弓根螺钉内固定(unilateral pedicle screw fixation,Ups)结合经椎间孔椎间融合(transforaminallumbar interbody fusio,TLIE)治疗腰椎退行性疾病的临床疗效. 方法 2009年12月至2010年12月,共收治不同类型腰椎退行性疾病患者42例,按照自愿的原则,采用Ups结合TLIF治疗24例和双侧椎弓根螺钉内固定术结合椎间融合术治疗18例.应用视觉模拟评分系统(Visual Analog Scale,VAS)评估患者术前、术后疼痛情况,应用Kim方法评价临床效果,应用Schulte方法观察植骨融合情况. 结果 所有患者术后临床症状较术前明显改善、临床疗效良好,无并发症的发生.VAS评分、Kim评分单侧固定优于双侧固定,Schulte方法观察植骨融合2组无显著差异.随访时间6~18个月,平均12

  10. Occipital Neuralgia after Occipital Cervical Fusion to Treat an Unstable Jefferson Fracture

    OpenAIRE

    Kong, Seong Ju; Park, Jin Hoon; Roh, Sung Woo

    2012-01-01

    In this report we describe a patient with an unstable Jefferson fracture who was treated by occipitocervical fusion and later reported sustained postoperative occipital neuralgia. A 70-year-old male was admitted to our center with a Jefferson fracture induced by a car accident. Preoperative lateral X-ray revealed an atlanto-dens interval of 4.8mm and a C1 canal anterior-posterior diameter of 19.94mm. We performed fusion surgery from the occiput to C5 without decompression of C1. The patient r...

  11. 后路固定椎间碎骨植骨与髂骨块植骨融合术治疗退行性腰椎不稳的临床研究%Clinical study of posterior internal fixation and iliac crest or granular bone grafting lumbar interbody fusion for the treatment of the degenerative lumbar instability

    Institute of Scientific and Technical Information of China (English)

    林斌; 林秋燕; 邵泽豹

    2012-01-01

    [Objective] To compare the clinical outcome of posterior pedicle screw fixation and iliac crest or granular bone grafting lumbar interbody fusion for the treatment of degenerative lumbar instability. [ Methods] There were 75 patients with degenerative lumbar disease. They were 41 males and 34 females, aged from 27 to 68 years with an average of 55. 6 years. Clinical manifestation; there were 72 cases with lower back pain and 47 cases with intermittent claudication. All of 75 cases had leg pain, including 37 cases of unilateral kg pain, 23 cases of bilateral leg pain and 15 cases of alternative leg pair.. Fifty - seven cases were positive with straight leg raising test, 66 cases had sensory disturbance, 58 cases had movement disorders, and 45 cases had abnormal achilles tendon reflex and knee jerk reflex, and 45 cases had injuries of cauda equina. There were 32 cases with degeneration of L4、5 , 26 cases with degeneration of L5S1 , 6 cases with degeneration of L3、4, and 11 cases with degeneration more than 2 segments. They were divided into two groups randomly: iliac bone group and granular bone group. The iliac bone group were treated with decompression, internal fixation for degenerative lumbar instability with pedicle screw and interbody fusion with iliac crest grafting. The granular bone group were treated with decompression, internal fixation and with granular bone grafting fusion. All of the cases had X -ray in routine and oblique view, CT and MRI preoperatively. The Japanese Orthopedic Association (JOA) score, Oswestry Disability Index (ODI) were evaluated before and 3, 6, 12 months after surgery. And fusion situation was evaluated by reviewing the roentgenographic film. [ Results] ( I ) Significant difference of JOA score and 0D1 were founded in each group before and after surgery. But it was no significant different between two groups. (2) The loss of intervertebral height was significant different between two group before and after surgery. The loss of

  12. 选择性椎间融合与椎弓根螺钉置入修复退变性腰椎侧凸:脊柱稳定性评价%Selective interbody fusion combined with pedicle screw fixation for degenerative lumbar scoliosis:spinal stability

    Institute of Scientific and Technical Information of China (English)

    尹承慧; 符臣学; 叶永平; 徐皓

    2015-01-01

    fusion should be conducted. This can achieve nerve decompression, spinal stability, and is relatively minimaly invasive. OBJECTIVE:To explore the efficacy of selective interbody fusion, limited neural decompression combined with pedicle screw system fixation for degenerative lumbar scoliosis. METHODS:Clinical characteristics of 53 patients with degenerative lumbar scoliosis were retrospectively analyzed, and the indication and contraindication were investigated. Selective interbody fusion, and limited neural decompression combined with pedicle screw system fixation were performed in the patients. Treatment effect and complication were analyzed. During folow-up, Suk standard was utilized to judge bone graft fusion. Before treatment and during final folow-up, lower back pain score system recommended by the Japanese Orthopaedic Association was used for assessment, and the excelent and good rate of curative effects was calculated. Cobb’s angle on the sagittal and coronal positions was compared and analyzed before and after treatment. RESULTS AND CONCLUSION:The patients were folowed up for 12 to 36 months. According to low back pain score of Japanese Orthopaedic Association Scores, the excelent and good rate of curative effect was 89% during the last folow-up. According to Suk standard, the fusion rate of vertebra was 94%. The last X-ray films revealed that Cobb’s angle was averagely (4.3±2.3)° (0°-13.5°) on the coronal plane after treatment, and the correction rate of scoliosis was 56%. The Cobb’s angle was averagely (45.1±12.5)° (10.4°-65.3°) after treatment, and the correction rate of lordosis was 36%. Complications after repair consisted of cerebrospinal fluid leakage in two cases, nerve injury in two cases, instrumental failure in one case, and pulmonary infection in one case, and symptomatic deep venous thrombosis in three cases. These findings suggest that selective interbody fusion, and limited neural decompression combined with pedicle screw system

  13. Preliminary results in anterior cervical discectomy and fusion with an experimental bioabsorbable cage – clinical and radiological findings in an ovine animal model

    OpenAIRE

    Daentzer, Dorothea; Floerkemeier, Thilo; Bartsch, Ivonne; Masalha, Waseem; Welke, Bastian; Hurschler, Christof; Kauth, Theresa; Kaltbeitzel, Daniel; HOPMANN, Christian; Kujat, Bernd; Kalla, Katharina

    2013-01-01

    Background Bioabsorbable implants are not widely used in spine surgery. This study investigated the clinical and radiological findings after anterior cervical discectomy and fusion (ACDF) in an ovine animal model with an experimental bioabsorbable cage consisting of magnesium and polymer (poly-ϵ-caprolactone, PCL) in comparison to a tricortical bone graft as the gold standard procedure. Materials and Methods 24 full-grown sheep had ACDF of C3/4 and C5/6 with an experimental bioabsorbable impl...

  14. Anterior fusion technique for multilevel cervical spondylotic myelopathy: a retrospective analysis of surgical outcome of patients with different number of levels fused.

    Directory of Open Access Journals (Sweden)

    Shunzhi Yu

    Full Text Available OBJECTIVE: The anterior approach for multilevel CSM has been developed and obtained favorable outcomes. However, the operation difficulty, invasiveness and operative risks increase when multi-level involved. This study was to assess surgical parameters, complications, clinical and radiological outcomes in the treatment of 2-, 3- and 4-level CSM. METHODS: A total of 248 patients with 2-, 3- or 4-level CSM who underwent anterior decompression and fusion procedures between October 2005 and June 2011 were divided into three groups, the 2-level group (106 patients, the 3-level group (98 patients and the 4-level group (44 patients. The clinical and Radiographic outcomes including Japanese Orthopedic Association (JOA score, Neck Disability Index (NDI score, Odom's Scale, hospital stay, blood loss, operation time, fusion rate, cervical lordosis, cervical range of motion (ROM, and complications were compared. RESULTS: At a minimum of 2-year follow-up, no statistical differences in JOA score, NDI score, Odom's Scale, hospital stay, fusion rate and cervical lordosis were found among the 3 groups. However, the mean postoperative NDI score of the 4-level group was significantly higher than that in the other two groups (P<0.05, and in terms of postoperative total ROM, the 3-level group was superior to the 4-level group and inferior to 2-level group (P<0.05. The decrease rate of ROM in the 3-level group was significantly higher than that in the 2-level group, and lower than that in the 4-level group (P<0.05. CONCLUSIONS: As the number of involved levels increased, surgical results become worse in terms of operative time, blood loss, NDI score, cervical ROM and complication rates postoperatively. An appropriate surgical procedure for multilevel CSM should be chosen according to comprehensive clinical evaluation before operation, thus reducing fusion and decompression levels if possible.

  15. Commentary on article: Laminoplasty versus laminectomy and fusion for multilevel cervical myelopathy: A meta-analysis of clinical and radiological outcomes by Chang-Hyun Lee et al

    Directory of Open Access Journals (Sweden)

    Nancy E Epstein

    2015-01-01

    Full Text Available Background: This is a commentary on the article laminoplasty versus laminectomy and fusion (LF for multilevel cervical myelopathy: A meta-analysis of clinical and radiological outcomes by Chang-Hyun Lee et al. Here, the authors utilized seven studies to compare the efficacy of cervical expansive laminoplasty (EL versus laminectomy and fusion (LF to address three or more level multilevel cervical spondylotic myelopathy (CSM. Both procedures led to similar degrees of neurological recovery and short-term loss of lordosis, but found that LF led to more favorable long-term results. Methods: For patients with three or more level CSM, laminectomy followed by an instrumented fusion (LF has major advantages; open bilateral decompression of the nerve roots, while minimizing the risk of inadvertent injury to the cord, and the fusion′s maintenance of lordosis. Results: Some would argue that inadvertent cord/root injury is greater utilizing any of the EL techniques; e.g., unilateral, bilateral, or spinous process splitting techniques. In short, why risk cord/root injury by manipulating the compressive posterior/posterolateral elements, which are already threatening neural function. Conclusion: Although the results of EL versus LF appeared comparable in the short-term in these seven articles, LF resulted in better long-term outcomes. Some would also argue that LF, utilizing an open approach offers safer bilateral neural exposure and decompression.

  16. Early clinical results of channel-assisted combined fixation and interbody fusion for treating lumbar vertebra diseases by muscle-splitting approach%通道下肌间隙入路椎间融合术治疗腰椎病变的近期疗效

    Institute of Scientific and Technical Information of China (English)

    曾忠友; 宋永兴; 吴鹏; 严卫锋; 籍剑飞; 张建乔; 毛克亚

    2015-01-01

    Objective To explore the feasibility and effectiveness of channel-assisted spatium intermusculare approach interbody fusion for treating lumbar vertebra diseases.Methods A total of 81 patients with lumbar vertebra diseases were treated from June 2012 to December 2013,including 35 males and 46 females between 29 and 76 years old with an average age of 54.6.There were 36 cases of lumbar disc degeneration,10 cases of recurrence in situ after lumbar disc herniation surgery,6 cases of huge lumbar disc herniation,11 cases of lumbar disc herniation with spinal canal stenosis,5 cases of extreme lateral lumbar disc herniation and 13 cases of lumbar degenerative spondylolisthesis.There were 67 cases of single segment lesion and 14 cases of two segment lesions.Lesion sites contained L1,2 in 1 case,L3,4 in 4 cases,L4,5 in 50 cases,L5S1 in 12 cases,L3,4 and L4,5 in 8 cases,and L4,5 and L5S1 in 6 cases.Results The length of incision was 2.42±0.45 cm in cases of single segment lesion and 4.28±0.38 cm in cases of two segment lesions.The operation time was 96.00±21.53 minutes and intraoperative blood loss was 347.50± 241.62 ml.During the operation,one case suffered from dural laceration,cerebrospinal fluid leakage and ipsilateral nerve root injury.Two cases suffered from pedicle fractures.Eight cases experienced epidermal necrosis of the incision.One case had poor wound healing.Three cases suffered from nerve injury.A total of 76 patients were followed up for 12-30 months,averagely 20.5 months.Intervertebral height of lesion segments was apparently recovered after surgery,and maintained in good condition during the final follow-up.No significant difference in the changes of area and grade of multifidus was detected 12 months after surgery and before surgery.Except 4 cases,the remaining had interbody fusion with a fusion rate of 94.7%.The balance between the coronal plane and sagittal plane of the lumbar spine was evidently improved.Average Japanese Orthopaedic Association

  17. Comparison of clinical outcome of two transforaminal lumbar interbody fusions for single-level degenerative lumbar disease%两种经椎间孔椎体间融合治疗单节段腰椎退行性疾病的疗效比较

    Institute of Scientific and Technical Information of China (English)

    刘新宇; 原所茂; 田永昊; 郑燕平; 王连雷; 李建民

    2015-01-01

    Objective To compare the clinical outcome of minimally invasive transforaminal lumbar interbody fusion (M-TLIF) and Wiltse-approach TLIF (W-TLIF) in treating single-level degenerative lumbar disease.Methods A retrospective review was performed on the 57 patients with single-level degenerative lumbar disorder managed via M-TLIF (n =27) and W-TLIF (n =30) from December 2009 to December 2010.In M-TLIF group degeneration at the L4-5 disc were noted in 11 cases and at the L5-S1 disc in 16 cases.And 19 cases were diagnosed with lumbar isthmus spondylolisthesis (17 with Grade Ⅰ spondylolisthesis and 2 with Grade Ⅱ spondylolisthesis),4 lumbar spinal stenosis and instability,2 lumbar disc herniation combined with huge posterior osteophytes,1 recurrent lumbar disc herniation after lumbar fenestration,and 1 recurrent lumbar spinal stenosis after decompression.In W-TLIF group degeneration at L4~5 disc were noted in 12 cases and at the L5-S1 disc in 18 cases.There were 19 cases diagnosed with lumbar isthmus spondylolisthesis (18 with Grade Ⅰ spondylolisthesis and 1 with Grade Ⅱ spondylolisthesis),3 with lumbar disc herniation,and 8 with lumbar spinal stenosis.Japanese Orthopedic Association (JOA) score and Visual Analogue Scale (VAS) were used to measure low back and leg pain.Modified Brantigan score was used to assess lumbar interbody fusion.Results Operative time was not significantly different between the two groups (P > 0.05).Incision length and mean blood loss were (5.1 ± 0.7) cm and (90.1 ± 10.5) ml in M-TLIF group,but were (6.9 ± 1.0)cm and (155.3 ±21.2)ml in W-TLIF group (P<0.05).At postoperative 1 and 3 days VAS in M-TLIF group was (2.1 ± 0.5) points and (1.0 ± 0.1) points respectively,but in W-TLIF group was (3.6 ± 0.1) points and (2.4 ± 1.0) points respectively (P < 0.05).Intraoperative X-ray fluoroscopy frequencies were (46 ± 9) times in M-TLIF group and (7 ± 2) times in W-TLIF group (P < 0.05).Mean period of follow-up was 26.7 months

  18. 显微手术切除及椎管固定融合治疗高颈段椎管哑铃型肿瘤%Microsurgery Treatment and Cervical Vertebral Fusion for Upper Cervical Dumbbell Tumor

    Institute of Scientific and Technical Information of China (English)

    段波; 秦军; 赵洪洋

    2013-01-01

    目的 探讨显微手术切除高颈段椎管哑铃型肿瘤及椎管固定融合的方法及效果.方法 回顾性分析11例高颈段椎管哑铃型肿瘤患者的临床资料,其中ToyamaⅡ型6例,Ⅲ型4例,V型1例.均行显微手术切除,其中远外侧入路3例,颈后正中入路8例.同时行椎管固定融合6例.结果 本组全切10例,次全切除1例.术后病理学诊断为神经纤维瘤9例,脊膜瘤2例.术后症状明显改善9例,改善2例,无感染及死亡病例.随访10例,平均时间27个月(3个月~3年),患者的症状和神经功能均有不同程度的改善,无颈椎不稳及后凸畸形. 结论 高颈段椎管哑铃型肿瘤显微手术切除并椎管固定融合能明显改善症状,安全性好,并发症少.%Objective To study the method and effect on microsurgical treatment and spinal fusion of upper cervical vertebral canal dumbbell tumors. Methods The clinical data of 11 cases suffered upper cervical dumbbell tumor was analyzed retrospectively, including 6 cases of type Ⅱ , 4 cases of type Ⅲ and 1 case of type Ⅴ according to Toyama typing. All 11 cases were performed microsurgery via far lateral approach in 3 cases and cervical posterior midline approach in 8 cases. Among them, 6 cases received spinal fusion. Results 10 cases were performed total resection and 1 case were performed subtotal resection. The post operative pathology exam revealed neurofibroma in 9 cases and spinal meningioma in 2 cases. The symptoms were improved in all cases without infection and death after operation. 10 cases were followed up for 3 months to 3 years( average 27 months). All symptoms and nerve function were improved without cervical vertebral instability and cervical kyphosis. Conclusion Microsurgical resection and spinal fusion can improve the symptoms obviously for dumbbell tumor in upper cervical spinal cord with better security and fewer complications.

  19. Efficacy of PEEK Cages and Plate Augmentation in Three-Level Anterior Cervical Fusion of Elderly Patients

    OpenAIRE

    Song, Kyung Jin; Kim, Gyu Hyung; Choi, Byeong Yeol

    2011-01-01

    Background To evaluate the clinical efficacy of three-level anterior cervical arthrodesis with polyethyletherketone (PEEK) cages and plate fixation for aged and osteoporotic patients with degenerative cervical spinal disorders. Methods Twenty one patients, who had undergone three-level anterior cervical arthrodesis with a cage and plate construct for degenerative cervical spinal disorder from November 2001 to April 2007 and were followed up for at least two years, were enrolled in this study....

  20. Curative effect and safety of posterolateral approach decompression and discectomy combined with in-terbody fusion and pedicle screw internal fixation for thoracic spinal stenosis%后外侧入路减压椎间植骨融合内固定治疗胸椎管狭窄症的疗效及安全性

    Institute of Scientific and Technical Information of China (English)

    曹俊明; 雷涛; 申勇; 丁文元; 张为; 杨大龙; 刘法敬; 康立星

    2014-01-01

    目的:探讨后外侧入路减压、椎间植骨融合、椎弓根螺钉内固定手术治疗胸椎管狭窄症的疗效及安全性。方法:2006年1月~2012年3月,收治单节段腹侧压迫致胸椎管狭窄症患者22例,男14例,女8例,年龄33~69岁,平均53.5岁。病程1~18个月,平均6.7个月。椎间盘突出部位:T7/81例,T8/94例,T9/109例, T10/118例。术前脊髓功能Frankel分级:B级5例,C级11例,D级6例。所有患者均行后外侧入路减压、椎间植骨融合、椎弓根螺钉内固定手术。采用Otani等评分系统进行术后疗效评估并计算临床优良率,评价治疗效果。结果:手术时间2.5~5h,平均3.2h,出血量400~1800ml,平均800ml。2例患者术后即刻有短暂脊髓功能障碍加重,经及时给予甲基强的松龙冲击、消肿、营养神经等治疗,分别于术后8h及24h开始逐渐恢复,其余20例患者术后即刻脊髓功能较术前恢复。术后随访24~60个月,平均40个月。末次随访时所有患者神经功能均明显改善,Frankel分级:C级3例,D级6例,E级13例。根据Otani等分级标准,优13例,良6例,可3例;优良率为86.36%。所有患者均获得骨性融合,均无内固定物松动、断裂等并发症发生。结论:后外侧入路减压、椎间植骨融合、椎弓根螺钉内固定手术治疗胸椎管狭窄症可取得良好的临床疗效,操作安全,并发症少。%Objectives: To study the efficacy and safety of the posterolateral approach decompression and discectomy combined with interbody fusion and pedicle screw internal fixation for the treatment of the thoracic spinal stenosis. Methods: Twenty two cases with the thoracic spinal stenosis undergoing the posterolateral de-compression and discectomy combined with interbody fusion were included in this group. There were 14 males and 8 females. The age ranged from 33 to 69 years old, with an average of 53.5 years. The course of

  1. Artrodese na coluna cervical utilizando SICAP como substituto de enxerto ósseo Artrodesis en la columna cervical utilizando SICAP como sustituto de injerto óseo Cervical spine fusion utilizing silicated calcium phosphate bone graft substitute (SICAP

    Directory of Open Access Journals (Sweden)

    Juliano Fratezi

    2011-01-01

    resembling natural bone. METHODS: 19 patients who underwent cervical spine fusion were retrospective

  2. Commentary on the effect of steroid use in anterior cervical discectomy and fusion surgery; a randomized controlled trial by Shiveindra B. et al. Journal of Neurosurgery Spine 2015;23:137-43

    OpenAIRE

    Nancy E Epstein

    2015-01-01

    Background: Steroids are often used in patients undergoing anterior cervical discectomy and fusion (ACDF) surgery to limit postoperative dysphagia. However, a major concern remains steroids′ impact is on fusion. Methods: In this prospective, randomized, double-blinded controlled study, the authors assessed the impact of steroids on swallowing/airway and fusion rates in 112 patients undergoing multilevel ACDF. The patients were randomly assigned to saline or dexamethasone groups prior to s...

  3. Posterior lumbar interbody fusion using B-Twin expandable spinal spacer with microendoscopic discectomy for lumbar disc herniation accompanying degenerative instability%椎间盘镜下B-Twin椎间融合治疗腰椎间盘突出症伴腰椎不稳

    Institute of Scientific and Technical Information of China (English)

    王博; 杨群; 张德强; 王宏; 吴春明; 马凯; 唐开; 刘阳

    2011-01-01

    Objective To explore the clinical outcomes of posterior lumbar interbody fusion using BTwin expandable spinal spacer with microendoscopic discectomy (MED) for lumbar disc herniation accompanying degenerative instability.Methods From March 2006 to May 2010,87 patients with lumbar disc heniation (only one level) accompanying degenerative instability were managed with posterior lumbar interbody fusion using B-Twin with MED,includeing 49 males and 38 females with an average of 47.6 years (range,37-65).Objective level located in L3,4 in 2 cases,L4,5 in 43,and L5S1 in 41.The patients were treated with single BTwin (Single group,n=51) and double B-Twin (Double group,n=36).Clinical outcomes were evaluated with surgical time,blood loss,visual analogue scale (VAS) scores,Oswestry disability questionnaire (ODI),and the pre- and post-operative disk space heights.Results The patients were followed up for an average of 35.8months (range,12-46).All the patients felt the low back pain and radiation pain disappeared or relieved apparently.The mean preoperative ODI and VAS scores decreased from 78%±3% to 18%±3%,and (8.70±11.3)to (0.65±10.48) at the final follow-up respectively.Disc space increased from a pre-operative height of (8.76±1.3) mm to a post-operative of (11.8±0.6) mm.ODI,VAS and the disk space heights in all patient showed statistical significance,which revealed no statistical significance between the two groups.However,the operation time,blood loss were statistical difference between the two groups.All the patients achieved solid union or probable union at a mean time of 5.6 months (range,3.9-8.6).Conclusion Posterior lumbar interbody fusion using B-Twin with MED can obtain satisfactory outcomes in the treatment of lumbar disc herniation accompanying degenerative instability.Single B-Twin can get similar clinical outcomes,but shorter surgical time,less blood loss,and less medical costs.%目的 探讨椎间盘镜下减压、B-Twin融合器植骨融合术治

  4. 丝素蛋白增强型磷酸钙复合rhBMP-2用于绵羊腰椎椎体间融合的实验研究%Experimental study on lumbar interbody fusion with silk fibroin enhanced calcium phosphate cement composite loaded with recombinant human bone morphogenetic protein-2 in sheep

    Institute of Scientific and Technical Information of China (English)

    陈亮; 顾勇; 陈晓庆; 干旻峰; 朱雪松; 杨惠林; 唐天驷

    2010-01-01

    Objective To evaluate the osteogenic characteristics of an injectable silk fibroin (SF) enhanced calcium phosphate cement (CPC) composite loaded with recombinant human bone morphogenetic protein-2 (rhBMP-2) on lumbar interbody fusion in sheep. Methods Twenty-four mature sheep were randomly divided into two groups. Each sheep underwent L1.2, L3.4 and L5.6 lumber interbody fusion, and the three disc spaces were randomly implanted with three of the following materials: SF/CPC, CPC/rhBMP-2, SF/CPC/rhBMP2 and autogenous iliac crest bone. One group was killed at 6 months and the other at 12 months. The fusion segments were observed and analyzed by manual palpation, CT scan, undestructive biomechanical testing, undecalcified histology, and histomorphology. Results The fusion rates of SF/CPC, CPC/rhBMP-2, SF/CPC/rhBMP-2 and autogenous bone assessed by manual palpation were 0, 33.33%, 55.56% and 77.78% respectively at 6 months. At 12 months, the fusion rates improved to 11.11%, 44.44%, 77.78% and 77.78%, respectively.The biomechanical results showed that fusion stiffness was significantly greater in autograft compared with SF/CPC/rhBMP-2, CPC/rhBMP-2, and SF/CPC in 4 degrees of freedom (flexion, extension, right bending, and left bending) at 6 months. The SF/CPC/rhBMP-2 composite showed similar stiffness as autograft, which was significantly greater than CPC/rhBMP-2 and SF/CPC at 12 nonths. Both CPC/rhBMP-2 and SF/CPC/rhBMP-2 showed significantly greater stiffness at 12 months compared with that of at 6 months. The results showed that bone volume was significantly greater in autograft compared with SF/CPC/rhBMP-2, CPC/rhBMP-2, and SF/CPC at 6 months. There was significant difference among ceramic residue among SF/CPC, CPC/rhBMP-2 and SF/CPC/rhBMP-2, with SF/CPC the greatest and SF/CPC/thBMP-2 the least. At 12 months, the bone volume of SF/CPC/rhBMP-2 composite was comparable with autograft, and greater than that of CPC/rhBMP-2 and SF/CPC. The bone volume of SF/CPC, CPC

  5. Adjacent segment degeneration after single-level anterior cervical decompression and fusion: disc space distraction and its impact on clinical outcomes.

    Science.gov (United States)

    Li, Jia; Li, Yongqian; Kong, Fanlong; Zhang, Di; Zhang, Yingze; Shen, Yong

    2015-03-01

    The purpose of this study was to find whether excessive distraction of the disc space for cage insertion was a risk factor for adjacent segment degeneration (ASD) after anterior cervical decompression and fusion (ACDF). One hundred and sixteen consecutive patients who underwent ACDF for single-level cervical disc herniation between June 2006 and November 2008 were retrospectively reviewed. Preoperative, postoperative and final follow-up disc height (DH), sagittal segmental alignment (SSA), and sagittal alignment of the cervical spine (SACS) were measured and compared between the ASD group and non-ASD group. In 116 patients, ASD was radiographically proven in 28 (24.1%) patients. The clinical outcomes were significantly improved compared to the preoperative scores in both groups. However, the postoperative and final follow-up DH of the ASD group were significantly higher than in the non-ASD group (p<0.05). In addition, the postoperative DH was significantly correlated with the postoperative or final follow-up SSA (p<0.05). However, postoperative DH was not found to significantly correlate with postoperative or final follow-up SACS (p=0.072 and p=0.096, respectively). Multivariate analysis showed that postoperative DH was the most significant risk factor for ASD. The clinical outcomes of ACDF for single-level degenerative cervical disc disease were satisfactory. Postoperative DH (the distracted distance) had the greatest impact on the incidence of ASD. Excessive disc space distraction is a considerable risk factor for the development of radiographic ASD.

  6. Fusion

    CERN Document Server

    Mahaffey, James A

    2012-01-01

    As energy problems of the world grow, work toward fusion power continues at a greater pace than ever before. The topic of fusion is one that is often met with the most recognition and interest in the nuclear power arena. Written in clear and jargon-free prose, Fusion explores the big bang of creation to the blackout death of worn-out stars. A brief history of fusion research, beginning with the first tentative theories in the early 20th century, is also discussed, as well as the race for fusion power. This brand-new, full-color resource examines the various programs currently being funded or p

  7. 单侧椎弓根钉固定结合单枚融合器治疗腰椎不稳症%Treatment of lumbar instability with transforaminal lumbar interbody fusion (with single cage) combined with uni-lateral pedicle screw fixation

    Institute of Scientific and Technical Information of China (English)

    华永均; 王人彦; 郭志辉; 朱利民; 陆建阳

    2014-01-01

    Objective:To explore the clinical effect of transforaminal lumbar interbody fusion (with single cage) combined with unilateral pedicle screw fixation in treating lumbar instability. Methods:The clinical data of 50 patients with lumbar in-stability were retrospectively analyzed. They underwent treatment and obtained following up more than 8 months from 2009 to 2012. All patients complicated with refractory or recurrent lower back pain ,and unilateral primarily or unilateral lower limb ra-diation pain,X ray and CT films showed lumbar instability. The patients were respectively treated with transforaminal lumbar interbody fusion (with single cage) combined with unilateral or bilateral pedicle screw fixation. According to different fixation methods,they divided into unilateral fixation group and bilateral fixation group. There were 20 patients with 22 intervertebral spaces in unilateral fixation group,8 males and 12 females,aged from 26 to 66 years old,2 cases with isthmic spondylolisthesis of degreeⅠ,8 cases with degenerative spondylolisthesis,10 cases with lumbar disc herniation;fusion location with L3,4 was in 1 case,L4,5 was in 12 cases,L5S1 was in 9 cases. There were 30 patients with 30 intervertebral spaces in bilateral fixation group,14 males and 16 females,aged from 41 to 62 years old,4 cases with isthmic spondylolisthesis of degree Ⅰ,14 cases with degenerative spondylolisthesis,12 cases with lumbar disc herniation;fusion location with L3,4 was in 3 cases,L4,5 was in 15 case,L5S1 was in 12 cases. Operation time,intraoperative blood loss,postoperative drainage,complications were analyzed and intervertebral height,lordosis angle changes,fusion rate and clinical effect were compared between two groups. Results:All incisions obtained primary healing,lower limb radiation pain and low back pain disappeared basically,no infection,endo-rachis injury was found. Foot drop occurred in one case of bilateral fixation group and no iatrogenic neurological symptom was

  8. Multisegmental cervical ossification of the posterior longitudinal ligament: Anterior vs posterior approach

    Directory of Open Access Journals (Sweden)

    Jain Subodh

    2005-01-01

    Full Text Available Aims : To determine the surgical approach in patients with multisegmental (four or more segments OPLL of the cervical spine. Methods and Materials : Data of 27 patients who had undergone either an anterior (corpectomy with excision of OPLL and interbody fusion=14 patients or posterior approach (laminectomy=12, laminoplasty=1 patient for the multisegmental cervical OPLL was analyzed retrospectively. The patients in each group were statistically similar in respect to preoperative factors such as age, duration of symptoms, preoperative modified Japanese orthopedic association score, OPLL thickness, effective canal diameter, and antero-posterior cord compression ratio. The clinical outcome was assessed by the Harsh grading system and recovery rate was assessed by Hirabayashi method. Results : There was no statistical difference in the outcome, and recovery rate. Nine patients developed complications after anterior approach in contrast to one after posterior approach. Conclusions : In patients with multisegmental cervical OPLL, there was no significant difference in the short-term recovery rate and outcome between two groups. The immediate postoperative complications were less in patients who had undergone posterior approach. From our analysis, it appears that the posterior approach is probably the preferred method of treatment in a multisegmental OPLL in absence of preoperative kyphosis.

  9. Axial Neck Pain after Cervical Laminectomy with Instrumented Fusion%颈椎椎板切除融合术后轴性疼痛

    Institute of Scientific and Technical Information of China (English)

    韩雨; 张永刚; 张雪松; 陆宁; 毛克亚; 崔庚; 王征

    2011-01-01

    目的:目前已证实颈椎椎板切除融合术是治疗多阶段的脊髓型颈椎病和后纵韧带骨化病的一种安全和有效的方法.然而,颈椎椎板切除融合术后经常发生颈部轴性疼痛.本研究的目的是观察C7棘突保留与否与颈椎椎板切除融合术后轴性疼痛的关系.方法:对2006年1月~2008年12月在我院行颈椎椎板切除融合术的67个病人进行回顾性分析.将这67个病人之中保留了C7棘突的29名病人称为A组,未保留C7棘突的38名病人称为B组,对两组病人的轴性症状、颈椎曲度和颈椎曲度指数(cervi cal curbatureindex,CCI)进行评估和比较.结果:在A组中有51.7%的病人发生了早期的轴性症状,10.3%的病人发生了晚期的轴性症状,B组分别为60.5%和42.1%.B组中42.1%的病人和A组中10.3%的病人在手术后晚期有轴性症状,A组的轴性疼痛发生率低于B组,有统计学意义(p=0.001).结论:保留C7棘突可以降低颈椎椎板切除融合术后轴性症状的发生率.%Objective: It has been demonstrated that cervical laminectomy with instrumented fusion is an effective and safe method of treating multi-level cervical spondylotic myelopathy and ossification of the posterior longitudinal ligament.However, axial neck pain is frequently encountered after cervical laminectomy with instrumented fusion.The aim of the present study was to determine clinical significance of the C7 spinous process on axial neck pain after cervical laminectomy with instrumented fusion.Methods: A total of 67 consecutive patients that underwent cervical laminectomy with instrumented fusion between Janurary 2006 and December 2008 were reviewed.The authors evaluated and compared axial neck pain 、 lordotic angle and cervical curbature index (CCI) in patients that underwent C7 spinous process preserving surgery (groupA n = 29) and in patients in which the C7 spinons process was sacrificed (groupB, n = 38).Results: Early axial pain occurred in 51.7% of

  10. Long-term outcomes and prognostic analysis of modified open-door laminoplasty with lateral mass screw fusion in treatment of cervical spondylotic myelopathy

    Directory of Open Access Journals (Sweden)

    Su N

    2016-08-01

    Full Text Available Nan Su, Qi Fei, Bingqiang Wang, Dong Li, Jinjun Li, Hai Meng, Yong Yang, Ai Guo Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Xicheng District, Beijing, People’s Republic of China Objectives: The purpose of the present study was to explore and analyze the long-term outcomes and factors that affect the prognosis of expansive open-door laminoplasty with lateral mass screw fusion in treatment of cervical spondylotic myelopathy (CSM. Methods: We retrospectively reviewed 49 patients with multilevel CSM who had undergone expansive open-door laminoplasty with lateral mass screws fixation and fusion in our hospital between February 2008 and February 2012. The average follow-up period was 4.6 years. The clinical data of patients, including age, sex, operation records, pre- and postoperation Japanese Orthopedic Association (JOA scores, cervical spine canal stenosis, and cervical curvature, were collected. Increased signal intensity (ISI on T2-weighted magnetic resonance imaging and ossification of the posterior longitudinal ligament were also observed. Paired t-test was used to analyze the treatment effectiveness and recovery of neuronal function. The prognostic factors were analyzed with multivariable linear regression model. Results: Forty-nine patients with CSM with a mean age of 59.44 years were enrolled in this study. The average of preoperative JOA score was 9.14±2.25, and postoperative JOA score was 15.31±1.73. There was significant difference between the pre- and postoperative JOA scores. The clinical improvement rate was 80.27%. On follow-up, five patients had complaints of neck and shoulder pain, but no evidence of C5 nerve palsy was found. Developmental cervical spine canal stenosis was present in all patients before surgery. Before surgery, ISI was observed in eight patients, while ossification of the posterior longitudinal ligament was found in 12 patients. The average of preoperative cervical

  11. 微创经椎间孔椎间融合术治疗35例腰椎退行性疾病的疗效分析%Analysis of the Efficacy of Minimally Invasive Transforaminal Lumbar Interbody Fusion in the Treatment of 35 Cases of Lumbar Degenerative Disease

    Institute of Scientific and Technical Information of China (English)

    杨林; 廖绪强; 赵新建; 吴锐辉; 曾志超; 李世渊

    2014-01-01

    Objective To explore minimally invasive transforaminal lumbar interbody fusion (MiTLIF) treatment of 35 cases of lumbar degenerative disease effect. Methods 70 cases of lumbar degenerative disease patients according to surgical indications and patient willingness divided into study group and the control group, 35 cases in each group. Study Groups MiTLIF treatment, the control group received conventional transforaminal lumbar fusion between (TLIF) treatment. Results The study group blood loss, intraoperative blood transfusion, postoperative drainage was significantly lower than the control group (P0.05). Study group VAS scores, time in bed than the control group (P0.05). Conclusion MiTLIF treatment of lumbar degenerative disease a significant effect, can effectively reduce surgical blood loss, intraoperative blood transfusion and postoperative drainage, improve postoperative pain conditions, reducing time in bed, safe, reliable, and suitable for clinical application.%目的:探讨微创经椎间孔椎间融合术(MiTLIF)治疗35例腰椎退行性疾病的疗效。方法将70例腰椎退行性疾病患者根据手术指征及患者意愿分为研究组与对照组,每组各35例。研究组采取MiTLIF治疗,对照组采取常规椎间孔腰椎间融合术(TLIF)治疗。结果研究组手术出血量、术中输血量、术后引流量明显低于对照组(P<0.05);两组手术时间对比,差异无统计学意义(P>0.05)。研究组术后VAS评分、卧床时间均优于对照组(P<0.05);JOA评分差异无统计学意义(P>0.05)。结论 MiTLIF治疗腰椎退行性疾病疗效显著,可以有效降低手术出血量、术中输血量及术后引流量,改善术后疼痛情况,减少卧床时间,安全可靠,适于临床推广与应用。

  12. Discover颈人工椎间盘置换术联合颈椎前路减压融合术治疗颈椎病的临床疗效%The clinic effect of discover cervical artificial disc replacement combined with anterior cervical decompression and fusion in treatment of cervical spondylosis

    Institute of Scientific and Technical Information of China (English)

    吴兴林

    2014-01-01

    Objective To explore the clinic effect of discover cervical artificial disc replacement combined with anterior cervical decompression and fusion in treatment of cervical spondylosis. Methods 96 patients were selected from our hospital,and the they were evenly divied into two group by random,experimental group patients were treated with discover cervical artificial disc replacement combined with anterior cervical decompression,the control group patients were treated with anterior cervical decompression and fusion.Compared and analyzed the two groups'cervical spine,the average hospital stay,postoperative cervical fixation time,normal activity recovery time and clinical effect after treatment. Results The experimental group's cervical average activity was (44.6±4.7) degree which was higher than control group,and the difference was significantly(P < 0.05);The experimental group was shorter than control group in average hospital stay,postoperative cervical fixation time,normal activity recovery time,and the difference was significantly(P < 0.05);Experimental group's total effective rate was 97.9% which was higher than the control group(87.5%),and the difference was significantly(P<0.05). Conclusion Discover cervical artificial disc replacement combined with anterior cervical decompression and fusion can reduce the average hospital stay,postoperative cervical fixation time,normal activity recovery time,can ensure the patients's cervical average activity to recover normal,and can improve the clinical effect.%目的:探讨分析Discover颈人工椎间盘置换术联合颈椎前路减压融合术的临床疗效。方法选择我院96例患者,将其随机均分为两组,实验组行Discover颈人工椎间盘置换术联和颈椎前路减压融合术治疗;对照组行颈椎前路减压融合术治疗,比较患者术后颈椎活动度、平均住院时间、术后颈椎固定时间、恢复正常活动时间以及患者临床疗效,并进行统计学分析。

  13. 椎间打压植骨联合棘突椎板复合体回植内固定治疗退变性腰椎不稳症%LUMBAR INTERBODY FUSION IMPACTED BONE GRAFTS COMBINED WITH REGRAFTING IN SITU WITH SPINOUS PROCESS AND VERTEBRAL PLATE COMPLEX AND PEDICLE SCREW FIXATION FOR LUMBAR DEGENERATIVE INSTABILITY

    Institute of Scientific and Technical Information of China (English)

    张超远; 孟祥翔; 秦晓彬; 付玉娟; 付鹏军

    2012-01-01

    Objective To evaluate the effectiveness of lumbar interbody fusion impacted bone grafts combined with regrafting in situ with spinous process and vertebral plate complex and pedicle screw fixation for lumbar degenerative instability. Methods Between January 1998 and October 2010, 48 patients with lumbar degenerative instability were treated by posterior decompression, lumbar interbody fusion impacted bone grafts combined with regrafting in situ with spinous process and vertebral plate complex and pedicle screw fixation. There were 26 males and 22 females, aged 52-76 years (mean, 62.4 years). The disease duration was 7 months to 25 years (mean, 6.5 years). One segmental instability was located at L3,4 in 1 case, at L4,5 in 10 cases, and at L5, S1 in 11 cases; multi-segmental instability was located at L3,4, L4,5, and L5, S1 in 5 cases, at L2,3 and L3,4 in 2 cases, at L3,4 and L4,5 in 10 cases, and at L4,5 and L5, S1 in 9 cases. Of 48 patients, 32 complicated by lumbar disc herniation, 46 by lumbar spinal stenosis, and 16 by degenerative scoliosis. The clinical results were evaluated by the Japanese Orthopaedic Association (JOA) score, recovery rate, disc height, and lumbar lordosis angles. Results The incisions obtained healing by first intention after operation. No nerve injury, rod or screw breakage, and infection occurred during and after operation. All 48 patients were followed up 1 to 6 years. The fusion time was 12-18 weeks (mean, 16.2 weeks). Vertebra slipping or degenerative scoliosis was corrected, and spinal column series became normal. At preoperation, 6 months after operation, and last follow-up, the disc heights were (5.2 ± 2.3), (11.9 ± 2.0), and (11.6 + 2.1) mm, respectively; the JOA scores were 3.2 + 2.1, 12.8 ± 1.6, and 13.6 + 1.2, respectively; and the lumbar lordosis angles were (-20.5 ± 10.5), (30.5 ± 8.5), and (31.2 + 5.6)°, respectively. The JOA scores, disc heights, and lumbar lordosis angles were significantly improved at 6 months after

  14. 锚定式颈椎椎间融合器在颈椎前路再手术中的应用%Clinical application research on anterior cervical reoperation by using of anchoring cervical intervertebral fusion cage

    Institute of Scientific and Technical Information of China (English)

    鲍达; 马远征

    2014-01-01

    目的:观察既往曾行颈椎前路手术的病例,再次行其他病变椎间盘切除减压并应用锚定式颈椎椎间融合器( anchoring cervical intervertebral fusion cage,ACIFC)行植骨融合的临床疗效。方法2009年1月~2012年6月收治颈椎前路手术后,其他颈椎节段再次发病患者12例,其中男7例,女5例;年龄35~64岁,平均49.6岁。再次手术原因:融合邻近节段退变性疾病8例,非邻近节段再发颈椎病3例,急性颈椎椎间盘突出症1例。均经前路行病变颈椎椎间盘切除减压、ACIFC植骨术,共置入ACIFC 12枚。术后定期行X线片及MRI复查;采用中华医学会骨科学分会( Chinese Orthopaedic Association, COA)40分法及颈椎残障指数( neck disability index, NDI)评分系统评价患者术前、术后颈脊髓神经功能及生活质量。结果随访时间2~4.5年,平均3.5年。12个再手术节段均获骨性融合,融合时间2.5~5个月,平均3.3个月。术前COA评分32.00±2.00分,术后末次随访时37.92±1.08分,差异有统计学意义(P<0.05)。术前NDI评分39.08±3.32,术后末次随访时29.08±2.15,差异有统计学意义(P<0.05)。结论在颈椎前路再手术中应用ACIFC行植骨融合,施术方便、固定确切、融合率高,近期随访结果满意。%Objective To study the clinical application of the anchoring cervical intervertebral fusion cage ( ACIFC ) , which was used in the anterior cervical reoperation.Methods All 12 cases of the cervical spinal diseases in another segments from January 2009 to June 2012 were reviewed, who were operated with anterior cervical decompression and fusion ( ACDF) before.There were total 7 male and 5 female, 35-64 years old (mean 49.6 years old).Adjacent segment disease(ASD), 8 cases, cervical spondylosis, 3 cases and 1 case was acute cervical disc herniation.All patients were treated with anterior dis

  15. Safety and Efficiency of Biomimetic Nanohydroxyapatite/Polyamide 66 Composite in Rabbits and Primary Use in Anterior Cervical Discectomy and Fusion

    OpenAIRE

    Hui Xu; Yan Wang; Xiaojing Su; Xuelian Zhang; Xuesong (Sonya) Zhang

    2014-01-01

    This study was conducted to validate the safety and efficiency of biomimetic nanohydroxyapatite/polyamide 66 (n-HA/PA66) composite in animal model (rabbit) and report its application in anterior cervical discectomy and fusion (ACDF) for 4, 12, and 24 weeks. N-HA/PA66 composite was implanted into one-side hind femur defects and the control defects were kept empty as blank controls. A combination of macroscopic and histomorphometric studies was performed up to 24 weeks postoperatively and compa...

  16. Anterior cervical decompression and fusion by microscope for the treatment of cervical spondylotic myelopathy%显微镜下减压融合术治疗脊髓型颈椎病

    Institute of Scientific and Technical Information of China (English)

    宋红浦; 郭峭峰; 张晓文; 张春

    2012-01-01

    目的:探讨显微镜下颈前路减压融合术治疗脊髓型颈椎病的疗效.方法:2005年2月至2010年3月,在显微镜辅助下经颈前路减压融合术治疗脊髓型颈椎病21例,男13例,女8例;年龄32~71岁,平均51.5岁;病程6个月~3年,平均12.5个月.手术操作:在显微镜下应用高速磨钻等工具进行减压操作,脊髓充分减压后取自体髂骨植骨融合加内固定.对手术前后JOA颈椎病评分进行比较并评价其疗效.结果:21例患者均获随访,时间18~24个月,平均20个月.患者脊髓神经功能均有不同程度提高,JOA评分由术前9.26±1.72增加至术后的13.64±1.38 (t=2.452,P=0.000).根据JOA评分评定疗效:优12例,良7例,一般2例.结论:显微镜下颈前路减压融合术具有操作精细、减压充分等优点,治疗脊髓型颈椎病安全、有效.%Objective: To explore clinical effects of anterior cervical decompression and fusion by microscope in treating cervical spondylotic myelopathy. Methods:From February 2005 to March 2010,21 patients with cervical spondylotic myelopathy, 13 males and 8 females with an average age of 51.5 years (ranged, 32 to 71) ,were treated with anterior cervical decompression using high-speed bur,then bone grafting and fusion with auto iliac bone and internal fixation by microscope. According to JOA score of cervical spondylosis to evaluate clinical effects before and after operation. Results: All patients were followed up from 18 to 24 months with an average of 20 months. JOA score improved significantly from preoperative 9.26±1.72 to postoperative 13.64±1.38 (t=2.452,P=0.000). According to JOA score, 12 cases were excellent,7 good and 2 fair. Conclusion : Anterior cervical decompression and fusion by microscope is a refined, safe and effective surgical procedure for cervical spondylotic myelopathy.

  17. Outcomes of minimally invasive transforaminal lumbar interbody fusion via Quadrant retractor versus conventional posterior open surgery for degenerative lumbar spine disease%微创经椎间孔减压腰椎融合内固定术与传统后路开放手术治疗腰椎退变性疾病的疗效比较

    Institute of Scientific and Technical Information of China (English)

    闫国良; 纪振钢; 高浩然; 李存孝; 史锦华; 李红; 刘海潮; 钱济先

    2013-01-01

    助于早期功能恢复.%Objectives: To compare clinical outcomes of minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF group) via MAST Quadrant retractor vs conventional posterior open surgery(open group) for degenerative lumbar spine disease. Methods: From March 2008 to June 2010, 80 patients with single-level lumbar degenerative disease and failed with conservative treatment were enrolled in this study. All cases were divided into two groups randomly, with 40 patients in each group. There was no significant difference in age, gender, body weight, clinical diagnosis or the segment between the two groups (P>0.05). Minimally invasive transforaminal lumbar interbody fusion via MAST Quadrant retractor or the conventional posterior open surgery was performed randomly. The operation time, blood loss, postoperative drainage, hospital stay, creatine phos-phokinase(CPK) in serum, MRI-T2 relaxation time, visual analogue scores (VAS) for back and leg pain, Os-westry disability index(ODl), and fusion rate by 24-36 months follow-up(mean time, 29 months) between two groups were compared. Results: The MIS-TLIF group had similar operation time to the open surgery group (141.0±27.3min vs 139.5±33.7min, P>0.05). Intraoperative blood loss, postoperative drainage in MIS-TLIF group was 268.0±122.2ml and 25.6±32.4ml, which was significantly less than 370.0±147.1ml and 277.8± 167.4ml of the open group, respectively (P0.05). The CPK levels were significantly higher at 1, 3, 5 days after surgery(P0.05). Conclusions: Minimally invasive transforaminal lumbar interbody fusion via MAST Quadrant retractor surgery and conventional posterior open surgery both can achieve a good short-term efficiency, but the former surgery had less soft tissue intervention, and conducive to early functional recovery.

  18. Anterior cervical discectomy with fusion in patients with cervical disc degeneration: a prospective outcome study of 258 patients (181 fused with autologous bone graft and 77 fused with a PEEK cage

    Directory of Open Access Journals (Sweden)

    Roenning Paal

    2010-03-01

    Full Text Available Abstract Background Anterior cervical discectomy with fusion (ACDF is challenging with respect to both patient selection and choice of surgical procedure. The aim of this study was to evaluate the clinical outcome of ACDF, with respect to both patient selection and choice of surgical procedure: fusion with an autologous iliac crest graft (AICG versus fusion with an artificial cage made of polyetheretherketone (PEEK. Methods This was a non-randomized prospective single-center outcome study of 258 patients who underwent ACDF for cervical disc degeneration (CDD. Fusion was attained with either tricortical AICG or PEEK cages without additional anterior plating, with treatment selected at surgeon's discretion. Radicular pain, neck-pain, headache and patient satisfaction with the treatment were scored using the visual analogue scale (VAS. Results The median age was 47.5 (28.3-82.8 years, and 44% of patients were female. 59% had single-level ACDF, 40% had two level ACDF and 1% had three-level ACDF. Of the patients, 181 were fused with AICG and 77 with a PEEK-cage. After surgery, the patients showed a significant reduction in radicular pain (ΔVAS = 3.05, neck pain (ΔVAS = 2.30 and headache (ΔVAS = 0.55. Six months after surgery, 48% of patients had returned to work: however 24% were still receiving workers' compensation. Using univariate and multivariate analyses we found that high preoperative pain intensity was significantly associated with a decrease in pain intensity after surgery, for all three pain categories. There were no significant correlations between pain relief and the following patient characteristics: fusion method (AICG or PEEK-cage, sex, age, number of levels fused, disc level fused, previous neck surgery (except for neck pain, previous neck trauma, or preoperative symptom duration. Two hundred out of the 256 (78% patients evaluated the surgical result as successful. Only 27/256 (11% classified the surgical result as a failure

  19. 模拟L4,5椎间盘脱出前路植入两种椎间融合器压缩应力应变的分析%Analyzing Compression Stress-strain by Analoging Implanting Two Interbody Fusion through L4,5 Disc Prolapse Anterior

    Institute of Scientific and Technical Information of China (English)

    吴丹凯; 李新颖; 李鹏

    2012-01-01

    To research the straining ..stressing distribution law of each measuring point of adjacent segment through implanting two kinds of inter - vertebral fusion cage into L4.5 inter - vertebral space in strain electrical measurement method, we could comparatively analyze the influence to the stress and strain of adjacent segments after implanting two inter - body fusion into L4.5 intervertebral space. 15 specimens of 3 months old 、body weight 90 - 100kg calf lumbar vertebrae ( L2.5) were token, then randomly divided into 5 normal control group 、5 L4.5 inter - vertebral disc implantation of xenogeneic bone cylindrical interbody fusion device group and 5 L4.5 inter -vertebral disc implantation of xenogeneic bone flat square inter - vertebral fusion device group. After resistance strain gauges being pasted in different parts of adjacent segments of each specimen L4.5 gap (front and rear) , we measured all straining value of each group specimen measuring point in a compressed state. The value of stress from the group of implanting xenograft bone cylindrical inter - body fusion and the group of implanting xenograft bone flat square column inter - body fusion were greater than that of normal control group ( P <0.05 ). The straining、 stressing value from the group of implanting xenograft bone cylindrical inter - body fusion device were greater than the group of implanting xenograft bone flat square intervertebral fusion device ( P < 0. 05 ) . After implanting inter - vertebral disc inter - vertebral fusion device, under compressive stressing, the value of adjacent segment changed. The implantation of inter -vertebral fusion device has played a great limited role in variation of adjacent segment stress. After implanting inter - body fusion, the variation of adjacent segment stress is an important reason to the degeneration of adjacent segments.%以应变电测量的方法研究二种椎间融合器植入L4.5椎间隙后,相邻节段各测点的应变、应力分布规

  20. 零切迹颈前路椎间融合固定系统在颈前路融合术中的初步应用%The primary clinical application of Zero-p anterior cervical intervertebral fusion system for cervical intervertebral fusion

    Institute of Scientific and Technical Information of China (English)

    贺瑞; 尚希福; 张文志; 胡业丰; 许翔; 姚刚; 李旭; 段丽群; 葛畅

    2012-01-01

    Objective To revaluate the clinical effect of zero-p anterior cervical intervertebral fusion system (zero-p ACIDfor cervical anterior intervertebral fusion. Method From 2009.12 to 2010.10,24cases of patients were treated surgically by zero-p ACIF. 22 cases of single-level, 2cas- es of two-level,incloud 7 cases cervical injury and 17 cases cervical spondylotic myelopathy. Result All cases obtained follow up with average of 14months (range 12 to 20 months),all cases have no postoperative dysphagia and tardive esophageal fistula. The disc height were achieved in final follow-up respectively. Place of intervertebral fusion system has no change or loose. Conclusion Zero-p ACIF has more excellent material and mechanical properties,can effectively maintain the fusion cage height and no effect on the prevertebral tissue. It is a new means of anterior cervical fusion.%目的 探讨零切迹颈前路椎问融合固定系统(Zero-p ACIF)在颈椎前路融合术中的应用效果.方法 2009-12-2010-10,对24例(26节段)颈椎疾病患者行前路椎问零切迹椎问融合固定系统内固定,其中颈椎外伤性椎间盘突出、不稳7例,颈椎问盘疾患17例,其中双节段2例.结果 24例患者随访12~20个月,平均随访14个月,JOA评分由术前平均8.6分上升到末次随访时15.2分,术后X线片与末次X线片提示椎间高度无丢失,内固定无松动.结论 Zero-p ACIF有较优异的材料和力学性能,能有效维持融合椎间高度,对椎前组织无影响,是一种新的颈前路融合手段.

  1. Artificial Cervical Disc Replacement Improves Mobility

    Medline Plus

    Full Text Available ... been utilized to perform anterior cervical discectomies and fusions. The fusion procedure has been the most common way to ... significant benefits over the previous procedure of the fusion, and that is, able to maintain motion of ...

  2. 颈前路非融合与融合技术联合应用治疗颈椎病%Anterior combination of non-fusion and fusion approach for cervical spondylosis

    Institute of Scientific and Technical Information of China (English)

    毛宁方; 赵颖川; 倪海健; 李明; 王传锋; 吴云刚; 白玉树; 朱晓东; 石志才

    2012-01-01

    目的:评价颈前路融合与非融合技术联合应用治疗颈椎病的临床疗效.方法:2008年3月~2010年6月期间,采用前路减压融合(anterior cervical discectomy and fusion,ACDF)术联合颈人工椎间盘置换术(cervical artificial disc replacement,C-ADR)治疗28例颈椎病患者,手术涉及二个椎间隙19例,涉及三个椎间隙9例,置换和融合为相邻间隙24例,非相邻间隙4例.术前、术后进行JOA评分和颈椎残障功能量表(neck disability index,NDI)评定,按Odom标准评定治疗效果.根据术前、术后、随访时的颈椎标准侧位X线片,观察植骨融合、内固定及人工椎间盘的情况.结果:手术均顺利完成,手术时间70~150min,平均85min;出血量50~300ml,平均180ml.1例患者术后出现轻度呼吸困难,对症处理后症状逐步好转.术后切口均Ⅰ期愈合,无椎动脉损伤及喉返神经损伤发生.经过14~39个月(平均22个月)随访,所有患者内置人物无松动、移位,植骨融合时间在3~8个月,平均4.5个月;所有人工椎间盘置换节段运动功能良好.术前JOA评分为10.3分,末次随访时为13.8分,平均改善率为52.2%;术前NDI评分为38.5分,末次随访时为22.3分,较术前显明改善(P<0.01).末次随访时接Odom标准评定手术疗效:优14例,良8例,尚可5例,差1例.结论:颈前路融合与非融合技术联合应用可综合两种技术的优点,在彻底减压的同时,减可少固定融合节段.%Objectives: To observe ihe clinical outcome of anterior combination of non-fusion and fusion approach for cervical spondylosis. Methods: Twenty-eight cases with cervical spondylosis (CS) undergoing combination of anterior cervical discectomy and fusion(ACDF) and cervical artificial disc replacement(C-ADR) between March 2008 and June 2010 were reviewed. Two levels of intervertebral discs were involved in 19 cases, while three levels were involved in 9 cases. The levels of fusion and non-fusion were adjacent in 24

  3. Evaluation of the 96/4 PLDLLA polymer resorbable lumbar interbody cage in a long term animal model.

    Science.gov (United States)

    Lazennec, Jean Y; Madi, Abdallah; Rousseau, Marc A; Roger, Bernard; Saillant, Gérard

    2006-10-01

    Arthrodesis using interbody cages has demonstrated high fusion rates. However, permanent cages are exposed to stress-shielding, corrosion, and may require explanation when necessary. Polylactic acid (PLA) bioresorbable cages are developed for avoiding these problems, but significant tissue reaction has been reported with 70/30 PLDLLA in some preclinical animal studies. The objective was to evaluate 96/4 PLDLLA cages in a sheep model over 3 years. Sixteen sheeps underwent one level anterior lumbar interbody fusion using 96/4 PLDLLA cages, filled and surrounded with cancellous bone graft from the iliac crest. Six groups of three animals were killed after 3, 6, 9, 12, 24, and 36 months. Harvested lumbar spine had radiographic, MRI, and CT evaluation and histological analysis. Histological results: cage swelling and slight signs of fragmentation associated to fibrocartilaginous tissue apposition at 3 months; bone remodeling around the cage with direct apposition of the mineralization front at 6 months; active cage degradation and complete fusion around the cage at 9 months; cage fragmentation and partial replacement by bone tissue at 12 months; bone bridges in and around the cage at 24 months; full resorption and intervertebral fusion at 36 months. Radiological results: partial arthrodesis at 3 months; definite peripheral arthrodesis at 6 months; similar aspect at 9 months; significant cage resorption at 12 months; definite inner and outer fusion at 24 months; complete cage resorption and calcification at the location of the cage at 36 months confirmed histological observations. Radiographic, CT scan, MRI, and histological data were consistent for showing progressive resorption of 96/4 PLDLLA, interbody fusion, and bone remodeling, with no significant signs of local intolerance reaction. These results are promising and suggest further development of 96/4 PLDLLA cages. PMID:16736199

  4. Safety and Efficiency of Biomimetic Nanohydroxyapatite/Polyamide 66 Composite in Rabbits and Primary Use in Anterior Cervical Discectomy and Fusion

    Directory of Open Access Journals (Sweden)

    Hui Xu

    2014-01-01

    Full Text Available This study was conducted to validate the safety and efficiency of biomimetic nanohydroxyapatite/polyamide 66 (n-HA/PA66 composite in animal model (rabbit and report its application in anterior cervical discectomy and fusion (ACDF for 4, 12, and 24 weeks. N-HA/PA66 composite was implanted into one-side hind femur defects and the control defects were kept empty as blank controls. A combination of macroscopic and histomorphometric studies was performed up to 24 weeks postoperatively and compared with normal healing. 60 cervical spondylosis myelopathy and radiculopathy patients who were subjected to ACDF using n-HA/PA66 and PEEK cage were involved in this study with six-month minimum follow-up. Their radiographic (cage subsidence, fusion status, and segmental sagittal alignment (SSA and clinical (VAS and JOA scales data before surgery and at each follow-up were recorded and compared. Nanohydroxyapatite/polyamide 66 composite is safe and effective in animal experiment and ACDF.

  5. 后路减压经椎间孔椎间融合术治疗钙化型高位腰椎间盘突出症的临床研究%Study of Transforaminal Lumbar Interbody Fusion in Patients with Calcified Upper Lumbar Intervertebral Disc Herniation

    Institute of Scientific and Technical Information of China (English)

    易泽洪; 肖波; 杨国奇; 刘光勇; 刘建伟; 蔡杰勇; 黄亮; 马俊; 权正学

    2014-01-01

    目的:探讨后路减压经椎间孔椎间融合术( transforminal lumbar interbody fusion,TLIP)治疗钙化型高位腰椎间盘突出症的临床疗效。方法2008年1月至2011年12月采用全椎板切除TLIP技术治疗的钙化型高位腰椎间盘突出症患者19例。男10例,女9例;年龄23~58岁,平均41.2岁。其中L1/24例,L2/38例,L3/47例。合并T12/L1突出1例,其余均为单间隙椎间盘突出。术前、末次随访时进行疼痛视觉模拟评分( VAS)、Oswestry功能障碍指数( ODI)评分,根据Otani方法评定疗效。结果所有病例获得随访,随访时间3~24个月,平均12个月。术中3例硬脊膜损伤,术后脑脊液漏,经加压包扎处理后痊愈,1例出现对侧神经牵拉症状,经对症处理后缓解。1例术后症状无恢复。术前VAS评分与ODI评分分别为(8.1±1.4)分、(57.79±1.90)%,末次随访 VAS 评分与 ODI 评分分别为(2.2±1.0)分、(20.53±0.3)%。均较术前有统计学差异(P0. 05). According to Otani’s criteria,the results were excellent in 9 ca-ses,good in 6 cases,improved in 3 cases,fair in 1 case,and poor in 1 case with an excellent and good rate of 78. 9%. Conclusion Posterior decompression TLIP is effective in the treatment of patients with calcified upper lumbar intervertebral disc herniation.

  6. Stability and interbody fusion of augmented pedicle screws with bone cement for lumbar spondylolisthesis accompanied with osteoporosis%骨水泥螺钉强化固定伴骨质疏松腰椎滑脱症的稳定性及椎间融合

    Institute of Scientific and Technical Information of China (English)

    姚珍松; 丁金勇; 唐永超; 陈康; 江晓兵; 梁德; 晋大祥; 庄洪; 张顺聪; 杨志东

    2016-01-01

    polymethylmethacrylate for lumbar spondylolisthesis accompanied with osteoporosis. METHODS: From June 2009 to June 2011, 27 patients suffering from lumbar spondylolisthesis accompanied with osteoporosis were included in this retrospective study. These patients received augmented pedicle screw with polymethylmethacrylate. The levels of disability and pain were evaluated by Oswestry Disability Index and visual analog scale. The internal fixation and fusion were evaluated by radiological findings. Al complications were recorded. RESULTS AND CONCLUSION: Al cases were fol owed up for 15-37 months. Oswestry Disability Index and visual analog scale scores were significantly better in final fol ow-up than that pre-treatment (P < 0.05). Imaging results revealed that bone cement tightly connected to bone interface. The position of screw and bone cement was good. Symptomatic bone cement leakage was not found. No fixation failure was detected during final fol ow-up. Al patients achieved interbody fusion. These results suggested that polymethylmethacrylate bone cement could increase the gripping force of the pedicle screw in osteoporotic vertebral body. It is safe and effective to treat spondylolisthesis accompanied with osteoporosis with augmented pedicle screws. Satisfactory fixation stability and interbody fusion can be obtained.

  7. Comparison of clinical efficacies of single segment transforaminal lumbar interbody fusion with cage versus autogenous morselized bone for degenerative lumbar spinal stenosis: a prospective randomized controlled study%椎间融合器植入与单纯自体颗粒骨植骨治疗退变性腰椎管狭窄症的比较

    Institute of Scientific and Technical Information of China (English)

    刘培盛; 刘小臻; 乔雪静; 都文楠; 罗大伟; 郑修军

    2014-01-01

    Objective To compare the clinical efficacies of single segment transforaminal lumbar interbody fusion (TLIF) with cage versus autogenous morselized bone for degenerative lumbar spinal stenosis.Methods A total of 87 patients undergoing single segment TLIF were randomly divided into 2 groups.A cage was implanted into intervertebral space in group A patients while autogenous morselized bone in group B patients.Operative duration,blood loss,length of stay and cost of hospitalization of two groups were recorded.They were followed up at 1 week,12,24 months post-operation.Oswestry disability index (ODI),visual analogue scale (VAS) fusion rates,intervertebral space and foramen height restoration,lumbar lordosis and postoperative complications were compared between two groups.Results No significant inter-group difference existed in operative duration,blood loss or length of stay.However,the average hospitalization cost in group A were 18% higher than that of group B (P < 0.05).Both groups achieved excellent clinical outcomes within 2 years.ODI,VAS score improvement rates and postoperative complication rates were not statistically different.Lumbar fusion rate was 86.7% in group A versus 85.7% in group B after 2 years.And there was no significant difference (P > 0.05).The heights of intervertebral space and foramen in group A achieved a better recovery than those of group B.Both groups had similar improvements of lumbar lordosis.Conclusion For degenerative lumbar spinal stenosis,usage of interbody cage is more effective in terms of recovery of intervertebral space and foraminal height compared with usage of bone graft.However it brings no better clinical efficacy while the usage of autogenous morselized bone is more cost-effective.Two grafting methods yield similar overall clinical outcomes.%目的 比较单节段经椎间孔腰椎椎间融合术(TLIF)手术中椎间融合器植入或单纯自体颗粒骨植骨两种融合方式治疗退变性腰椎管

  8. Clinical outcome of cervical disc replacement and adjacent cage fusion for multi-segmental cervical disc herniation%颈椎间盘置换与相邻节段融合的治疗选择

    Institute of Scientific and Technical Information of China (English)

    任先军; 初同伟; 蒋涛; 王卫东; 王建; 李长青

    2011-01-01

    目的 探讨椎间盘置换与相邻节段融合治疗多节段颈椎间盘突出症的临床疗效.方法 对39例多节段颈椎间盘突出症患者,Ⅰ期同时完成病变节段人工椎间盘置换和邻近节段Cage融合.本组39例多节段椎间盘突出症患者,双节段颈椎间盘突出29例,三节段颈椎间盘突出9例,四节段颈椎间盘突出1例.病变节段C3~4、C4~5,2例,C4~5、C5~6 15例,C5~6、C6-79例,C4~5、C6~7 3例,C3~4、C4~5、C5~6 4例,C4~5、C5~6、C6~7 5例,C3~4、C4~5、C5~6、C6~7 1例.临床症状以脊髓压迫为主者18例,以神经根性症状为主者21例,术后随访观察椎间盘假体稳定性、假体活动度、Cage融合状态及Cage位移等.依据日本骨科学会(JOA)评分,Odom标准评定神经功能改善情况,采用颈椎残障功能量表(neck disability index,NDI)评定术后临床症状改善和日常功能状态.结果29例双节段颈椎间盘突出症患者,选择1个节段的椎间盘置换和1个节段Cage植骨融合;9例三节段颈椎间盘突出症患者,7例行1个节段的人工椎间盘置换、2个节段Cage植骨融合;2例选择2个节段的人工椎间盘置换、1个节段Cage植骨融合.1例四节段颈椎间盘突出症患者行2个节段的人工椎间盘置换、2个节段Cage植骨融合.术后随访6个月~3年半,人工椎间盘稳定,椎间盘假体平均活动度为9.3°,Cage全部融合,无Cage松动沉陷.患者神经功能有明显改善,JOA评分由术前9.1分增加至13.2分;NDI评分由术前41.8分降至29.5分;Odom评分临床成功率(优/良/可)达到85%(33例).结论颈椎间盘置换与相邻节段融合为颈椎间盘突出症的治疗提供了新的选择方式,兼顾了颈椎的稳定和运动功能,其远期疗效有待于临床随访.%Objective To evaluate the clinical outcome of artificial cervical disc replacement and cage fusion in the treatment of multi-segmental cervical disc herniation. Methods A total of 39

  9. Comparing precision of distortion-compensated and stereophotogrammetric Roentgen analysis when monitoring fusion in the cervical spine

    OpenAIRE

    Leivseth, Gunnar; Kolstad, Frode; Nygaard, Øystein P; Zoega, Björn; Frobin, W; Brinckmann, P.

    2005-01-01

    Two methods to measure sagittal plane segmental motion in the cervical spine are compared. Translational and rotational motion was measured in nine cervical motion segments of nine patients by distortion-compensated (DCRA) as well as by stereophotogrammetric Roentgen analysis (RSA). To compare measurement precision of the new DCRA protocol with the established RSA technique under realistic clinical conditions and to discuss advantages and disadvantages of both methods in clinical studies. RSA...

  10. Retrospective analysis of transforaminal lumbar interbody fusion for the treatment of acute and chronic lumbar intervertebral disc injury%经椎间孔椎间融合固定治疗急慢性腰椎间盘损伤回顾性分析

    Institute of Scientific and Technical Information of China (English)

    孙俊; 汪颖峰; 罗俊杰

    2011-01-01

    Objective To summary the effect of treatment of lumbar intervertebral disc in acute and chronic injury by transforaminal lumbar interbody fusion ( transforaminal lumbar interhody fusion , TLIF). Methods From in July 2007 to October 2010 , application of bilateral partial laminectomy decompression underwent TLIF fixation , treatment of lumbar intervertehral disc in 10 cases of acute and chronic injury in a total of 12 segments of 6 males and 4 females , aged 38-72 years , mean age 51 years.Lumbar degenerative changes associated with nerve root canal stenosis in 1 case, 3 cases of chronic lumbar spondylolisthesis , acute traumatic spondylolisthesis with bilateral nerve root injury in 2 , lumbar disc hemiation with lumbar instability in 4 cases. Results All patients with no neurological complications were followed up for 10 (6 to 48 months ) months . according to Denis pain ratings ,JOA score , mean postoperative improvement rate of 90%. Conclusion TLIF method can obtain the full relief under the premise of the immediate stability of the spine bone graft done at the same time , fusion rate and few complications, for lumbar intervertebral disc with acute and chronic injury , the effects are short-term clinical affirm.%目的 总结经椎间孔椎间融合术(TLIF)治疗腰椎间盘急慢性损伤的疗效.方法 2007年7月-2010年10月应用双侧椎板部分切除减压后行TLIF融合固定,治疗腰椎间盘急慢性损伤10例共12个节段,男6例,女4例,年龄38~72岁,平均年龄51岁.腰椎退行性变伴神经根管狭窄1例,慢性腰椎滑脱3例,急性外伤性腰椎滑脱伴双侧神经根损伤2例,腰椎间盘突出合并腰椎失稳4例.结果 全部患者均未出现神经系统并发症,平均随访10(6~48个月)个月,根据Denis疼痛分级、JOA评分法,术后平均改善率90%.结论 TLIF方法 可在充分减压的前提下获得脊柱的即刻稳定同时完成植骨,融合率高,并发症少,用于腰椎间盘急、慢性损伤中、短期随访临床效果肯定.

  11. 腰椎融合术对脊柱-骨盆矢状面平衡及疗效的临床观察%Clinical observation and efficacy on lumbar interbody fusion for spine pelvic sagittal balance

    Institute of Scientific and Technical Information of China (English)

    罗江洪; 李伟; 陆庭盛

    2015-01-01

    Objective To analyze the clinical therapeutic effect of lumbar fusion in the treatment of lumbar degenerative diseases in the spine pelvic sagittal balance. Methods From June 2009 to June 2012,the clinical data of 92 cases with lumbar degenerative diseases ac-cepted lumbar spinal fusion operation in our hospital was collected. The contrast lumbar lordosis ( LL) ,lumbar sagittal vertical axis ( SVA) , pelvic incidence angle ( PI) ,sacral inclination angle ( SS) ,pelvic tilt angle ( PT) and other numerical parameters,using the Oswestry disabil-ity index ( ODI) ,visual analogue scale ( VAS) and the Japan Society of Department of orthopedics ( JOA) score were followed up two years after operation,and the postoperative effect was evaluated. Results The spinal pelvic parameters SVA,LL,SS and PT after surgery were changed obviously,and the difference was statistically significant(P<0. 05). The postoperative follow-up of VAS,ODI and JOA score were better than that of preoperation,the difference was significant(P<0. 05). Conclusion Lumbar fusion operation can restore lumbar lordosis, to maintain the spine pelvic sagittal balance and improve the effect of operation,and have positive significance to improve the postoperative symptoms.%目的:探讨腰椎退变性疾病采用腰椎融合术治疗对脊柱-骨盆矢状面平衡及临床疗效分析。方法收集2009年6月至2012年6月我院骨科接受腰椎内固定融合手术的92例腰椎退行性疾病患者的临床资料,术后2年内随访患者,对比腰椎前凸角( LL)、腰椎矢状垂直轴( SVA)、骨盆入射角( PI)、骶骨倾斜角( SS)、骨盆倾斜角( PT)等参数数值,采用Oswestry功能障碍指数( ODI)、视觉模拟评分法( VAS)及日本骨科学会( JOA)评分,评估术后疗效。结果脊柱骨盆参数SVA、LL、SS及PT手术后均较术前有明显改变,且差异有统计学意义(P<0.05),术后随访VAS、ODI及JOA 评分,均较术前有明显改善,治疗

  12. Adjacent segment disc degeneration after lumbar interbody fusion:a systematic review%腰椎融合术后发生邻近节段椎间盘退变的系统评价

    Institute of Scientific and Technical Information of China (English)

    郝俊龙; 陈永刚; 夏亚一; 汪玉良; 王栓科; 汪静; 王翠芳; 耿彬

    2011-01-01

    [ Objective] To assess the efficacy and safety of bone morphogenetic protein for fractures. [ Methods] We searched the Cochrane Central Register of Controlled Trials (CENTRAL) ( Issue 3, 2010) , MEDLINE, EMBASE, CBM,CNKI, VIP, Wanfang database, etc. from their inception to June 2010. Some relevant journals were handsearched as well. Two reviewers independently evaluated the quality of included studies and extracted the data. Meta - analysis was performed by RevMan 5.0 software. [ Results ] Four trials involving 451 patients were included. Meta analysis showed that as for functional training, lumbar fusion increased risk of adjacent segment disc degeneration (ASD) . The incidence of ASD after lumbar laminectomy is higher than non - laminectomy. The existence of ASD preoperative increased risk of postoperative ASD. The incidence of ASD had no relation with internal fixation or the number of fusion segments. [ Conclusion ] Lumbar fusion can increase the incidence of ASD, and is related with laminectomy and the existence of preoperative ASD, but is not related with internal fixation and the number of lumbar fusion segments. However, there is a moderate possibility of selection bias, performance bias and publication bias in this review because of the small number of the included studies, which may weaken the strength of the evidence of our results. More large sample size, high -quality RCTs are needed.%[目的]对腰椎融合术加速邻近节段椎间盘退变进行系统评价.[方法]按照Coehrane协作网制订的检索策略进行检索,计算机检索MEDLINE(1966~2010年8月)、EMBASE(1974~2010年8月)、Cochrane图书馆(2010年第8期)、中国生物医学文献数据库(CBM,1978~2010年8月)、中国期刊全文数据库(CNKI,1994~2010年8月)、中文科技期刊全文数据库(VIP,1989~2010年8月)及万方数据库(1979~2010年8月).手工检索相关的中英文骨科杂志和会议论文.纳入腰椎融合术后发生邻近节段椎间盘

  13. 微创腰椎经椎间孔椎体间融合术的并发症分析:131例病例回顾和文献复习%Perioperative complications of minimally invasive transforaminal lumbar interbody fusion: retrospective study for 131 cases and literature review

    Institute of Scientific and Technical Information of China (English)

    吴文坚; 梁裕; 张兴凯; 曹鹏; 陈新用; 郑涛

    2012-01-01

    Background: Though minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) has been widely used in the surgical treatment of lumbar degenerative disease with satisfactory results, it may have more complications. Objective: The purpose of the present study is to evaluate the incidence of the complications of MIS-TLIF and to investigate its reasons and prevention. Methods: A retrospective analysis was performed on 131 consecutive cases of minimally invasive surgery-transforarainal lumbar interbody fusion (MIS-TLIF) from January 2010 to May 2011. The operation time, intra-operative blood loss, post-operative hospitalization and the peri-operative complications were recorded. The visual analog scale ( VAS) for back pain, Oswestry disability index (ODI) and Japanese Orthopaedic Association (JOA) score for functional evaluation were recorded preoperatively, 3 months postoperatively and at the final follow-up. Results: Mean follow-up duration was 8. 3 months. Average operation time was (146. 4 ± 36. 9) min, average intra-operative blood loss was (176. 7 ± 86. 1) ml and average post-operative hospital stay was (4.4 ± 1.6) d. The VAS for back pain, ODI and JOA score were all significantly improved after surgery and at the final follow-up. Complications happened in 16 patients; 1 case with post-operative hematoma; 6 cases of dura tearing (4. 6% ) without CSF leakage, with a higher risk for cases of bilateral decompression via unilateral approach (P =0.012); 6 cases of screw malposition; 1 case of drop foot for unknown causes; lease of pulmonary infection and 1 case of urinary retention for elderly patient. Conclusions: MIS-TLIF in the treatment of lumbar degenerative disc disease is safe and effective. The incidence of complications is low and correlated more with the feature of the technique, the learning curve and the patient selection. Surgical technique training and patient selection are critical for the prevention of peri-operative complications. If

  14. Off-label innovation: characterization through a case study of rhBMP-2 for spinal fusion.

    Science.gov (United States)

    Schnurman, Zane; Smith, Michael L; Kondziolka, Douglas

    2016-09-01

    OBJECTIVE Off-label therapies are widely used in clinical practice by spinal surgeons. Some patients and practitioners have advocated for increased regulation of their use, and payers have increasingly questioned reimbursment for off-label therapies. In this study, the authors applied a model that quantifies publication data to analyze the developmental process from initial on-label use to off-label innovation, using as an example recombinant human bone morphogenetic protein 2 (rhBMP-2) because of its wide off-label use. METHODS As a case study of off-label innovation, the developmental patterns of rhBMP-2 from FDA-approved use for anterior lumbar interbody fusion to several of its off-label uses, including posterolateral lumbar fusion, anterior cervical discectomy and fusion, and posterior lumbar interbody fusion/transforaminal lumbar interbody fusion, were evaluated using the "progressive scholarly acceptance" (PSA) model. In this model, PSA is used as an end point indicating acceptance of a therapy or procedure by the relevant scientific community and is reached when the total number of peer-reviewed studies devoted to refinement or improvement of a therapy surpasses the total number assessing initial efficacy. Report characteristics, including the number of patients studied and study design, were assessed in addition to the time to and pattern of community acceptance, and results compared with previous developmental study findings. Disclosures and reported conflicts of interest for all articles were reviewed, and these data were also used in the analysis. RESULTS Publication data indicated that the acceptance of rhBMP-2 off-label therapies occurred more rapidly and with less evidence than previously studied on-label therapies. Additionally, the community appeared to respond more robustly (by rapidly changing publication patterns) to reports of adverse events than to new questions of efficacy. CONCLUSIONS The development of off-label therapies, including the

  15. 后方韧带复合体对腰椎椎间融合术后早期相邻节段退变的影响%Effect of the Posterior Ligament Complex on the Adjacent Segment Degeneration after Posterior Lumbar Interbody Fusion

    Institute of Scientific and Technical Information of China (English)

    何方生; 吴兵; 盛文辉; 王春辉; 王自刚; 尚琦松; 韩鹏远; 陈操

    2016-01-01

    目的 探讨后方韧带复合体对腰椎椎间融合术后早期相邻节段退变的影响.方法 2000年1月至2010年1月在我科实施后路腰椎减压椎间融合内固定治疗L4~5椎间盘突出患者60 例.A组(30 例)行保留后方韧带复合体的腰椎椎间融合术( posterior lumbar interbody fusion,PLIF),B组(30 例)行切除后方韧带复合体的PLIF术.比较两组手术前、后日本骨科协会( Japanese orthopaedic association,JOA)评分及改善率.术前、末次随访时测量腰椎X线片上L3~4椎间盘的高度和椎间隙动态角度、L3~4椎体滑移距离并进行比较.术前及末次随访时对L3~4椎间盘进行Pfir-rmann分级.结果 手术前、后两组患者的JOA评分差异有统计学意义( P0. 05),两组之间改善率差异无统计学意义(P>0. 05).A组9 例患者出现了L3~4节段的邻近节段退变( adjacent segment disease,ASD),B组17 例出现了L3~4节段的ASD.其中A、B两组均有2 例患者为有症状的ASD.术前两组患者X线片上L3~4椎间盘的高度、椎间隙动态角度、L3~4椎体滑移距离相比差异均无统计学意义( P>0. 05),而末次随访时差异有统计学意义( P0. 05). A group had 9 patients with lumbar 3/4 segment of the ASD,B group had 17 cases of lumbar 3~4 segment ASD. Among them,each groups had 2 cases of patients with symptoms of ASD. There were not difference in 3~4 lumbar intervertebral disc height,intervertebral space dy-namic angle ,waist 3 ~ 4 vertebral slip distance . But at the time of last follow - up significant difference could be found( P <0. 05). At the end of the follow-up A group had 6 cases of Pfirrmann grade 1,22 cases of 2,2 cases of grade 3,no 4,5 cases. Bgroup had 4 cases of Pfirrmann grade 1,24 cases of 2,2 cases of grade 3,no 4,5 cases.Conclusion Inlumbarinterbody fusion,posterior ligament complex can decrease the incidence of adjacent segment degeneration.

  16. Cervical Spondylotic Myelopathy: Factors in Choosing the Surgical Approach

    OpenAIRE

    Yalamanchili, Praveen K.; Vives, Michael J.; Chaudhary, Saad B.

    2012-01-01

    Cervical spondylotic myelopathy is a progressive disease and a common cause of acquired disability in the elderly. A variety of surgical interventions are available to halt or improve progression of the disease. Surgical options include anterior or posterior approaches with and without fusion. These include anterior cervical discectomy and fusion, anterior cervical corpectomy and fusion, cervical disc replacement, laminoplasty, laminectomy with and without fusion, and combined approaches. Rec...

  17. The learning curve of minimally invasive transforaminal lumbar interbody fusion hybrid using pedical screws and translamina facet screw system%微创经椎间孔腰椎体间融合术采用混合内固定的学习曲线

    Institute of Scientific and Technical Information of China (English)

    肖波; 毛克亚; 王岩; 肖嵩华; 张永刚; 张西峰; 张雪松; 王征; 崔庚

    2013-01-01

    目的:探讨微创经椎间孔腰椎体间融合术(minimally invasive transforaminal lumbar interbody fusion,MIS-TLIF)采用椎弓根螺钉结合经椎板关节突螺钉混合内固定的学习曲线.方法:回顾性分析我院2009年10月~2011年7月收治的48例单节段腰椎退变性疾病患者,采用单侧切口进行MIS-TLIF手术,置入单侧椎弓根螺钉后同一切口向对侧置入经椎板关节突螺钉,按时间先后顺序分成A~D四组,每组12例.对手术时间、术中出血量、手术并发症、置入经椎板关节突螺钉失败率、融合率及术后疗效进行组间比较.结果:随访时间12~30个月,平均16.3个月.手术时间A组为139.17±18.32min,B组为115.00±14.62min,C组为110.83±11.04min,D组为110.83±18.32min;术中出血量A组为140.83±33.76ml,B组为83.33±28.39ml,C组为69.17±25.03ml,D组为64.17±25.75ml.B、C、D三组的手术时间和术中出血量均明显小于A组,差异有显著性(P<0.05),而B、C、D三组组间差异无显著性(P>0.05).A组出现并发症3例(25.0%),其中2例硬膜囊破裂和1例神经损伤;B组发生l例硬膜囊破裂(8.3%),C、D组无并发症;A组置入经椎板关节突螺钉失败2例(16.7%),B组失败1例(8.3%),C、D组无失败病例;4组均无不融合病例.四组间并发症发生率、经椎板关节突螺钉置钉失败率及融合率差异无显著性(P>0.05).术前腰痛/腿痛VAS评分A组为4.3±3.2分/5.5±3.1分,B组为4.5±3.8分/6.8±3.7分,C组为4.1±3.5分/5.7±3.6分,D组为4.8±3.1分/6.3±4.1分;术后1年时A组为1.3±1.1分/0.4±0.3分,B组为1.4±0.9分/0.3±0.2分,C组为1.2±0.8分/0.3±0.4分,D组为1.4±1.0分/0.2±0.2分.术前ODI评分A组为(40.2±8.1)%,B组为(45.4±9.7)%,C组为(43.2±7.9)%,D组为(39.2±8.4)%;术后1年时A组为(15.2±8.7)%;B组为(14.8±9.4)%;C组为(13.9±8.6)%;D组为(14.1±7.9)%.各组腰痛、腿痛VAS评分及ODI评分术后1年较术前显著改善(P<0.05),而

  18. Tissue identification with micro-magnetic resonance imaging in a caprine spinal fusion model

    NARCIS (Netherlands)

    M.P. Uffen; M.R. Krijnen; R.J. Hoogendoorn; G.J. Strijkers; V. Everts; P.I. Wuisman; T.H. Smit

    2008-01-01

    Nonunion is a major complication of spinal interbody fusion. Currently X-ray and computed tomography (CT) are used for evaluating the spinal fusion process. However, both imaging modalities have limitations in judgment of the early stages of this fusion process, as they only visualize mineralized bo

  19. Prevalence of adjacent segment disc degeneration in patients undergoing anterior cervical discectomy and fusion based on pre-operative MRI findings.

    Science.gov (United States)

    Lundine, Kristopher M; Davis, Gavin; Rogers, Myron; Staples, Margaret; Quan, Gerald

    2014-01-01

    Anterior cervical discectomy and fusion (ACDF) is a widely accepted surgical treatment for symptomatic cervical spondylosis. Some patients develop symptomatic adjacent segment degeneration, occasionally requiring further treatment. The cause and prevalence of adjacent segment degeneration and disease is unclear at present. Proponents for motion preserving surgery such as disc arthroplasty argue that this technique may decrease the "strain" on adjacent discs and thus decrease the incidence of symptomatic adjacent segment degeneration. The purpose of this study was to assess the pre-operative prevalence of adjacent segment degeneration in patients undergoing ACDF. A database review of three surgeons' practice was carried out to identify patients who had undergone a one- or two-level ACDF for degenerative disc disease. Patients were excluded if they were operated on for recent trauma, had an inflammatory arthropathy (for example, rheumatoid arthritis), or had previous spine surgery. The pre-operative MRI of each patient was reviewed and graded using a standardised methodology. One hundred and six patient MRI studies were reviewed. All patients showed some evidence of intervertebral disc degeneration adjacent to the planned operative segment(s). Increased severity of disc degeneration was associated with increased age and operative level, but was not associated with sagittal alignment. Disc degeneration was more common at levels adjacent to the surgical level than at non-adjacent segments, and was more severe at the superior adjacent level compared with the inferior adjacent level. These findings support the theory that adjacent segment degeneration following ACDF is due in part to the natural history of cervical spondylosis.

  20. 腰椎经后路椎体间融合后单边或双边固定对邻近节段退变的影响%Comparative study of adjacent segment degeneration after posterior lumbar interbody fusion with unilateral or bilateral pedicle screw instrumentation

    Institute of Scientific and Technical Information of China (English)

    林斌; 张文彬; 周琴; 张峰; 敖庆芳; 俞辉; 陆成武

    2014-01-01

    背景:在行后路椎体融合内固定术中,椎弓根钉置入不可避免会损伤邻近关节突关节。目前一致认为单边固定因保留一侧关节突关节可明显降低邻近节段退变的发生率,但仍缺乏对邻近节段退变的影响因素及不同节段退变发生率的长期随访研究。  目的:对比经后路椎体间融合术(posterior lumbar interbody fusion,PLIF)后单边或双边椎弓根螺钉固定对邻近节段退变的影响。  方法:2006年2月至2007年12月,101例行PLIF手术的L4-L5椎间盘突出症患者纳入本研究。采用单边固定42例,双边固定59例。所有患者术后随访时间均超过5年。邻近节段分为三个节段:第1个近端邻近节段、第2个近端邻近节段及远端邻近节段。依据末次随访的影像学资料评估邻近节段退变的情况,并记录末次随访时的ODI评分评价腰椎功能。  结果:单边固定组第1个近端邻近节段、第2个近端邻近节段及远端邻近节段退变的发生率分别为57.1%(24/42)、45.2%(19/42)、38.1%(16/42);双边固定组第1个近端邻近节段、第2个近端邻近节段及远端邻近节段退变的发生率分别为72.9%(43/59)、68.0%(40/59)、50.8%(30/59)。两组第1个近端邻近节段和远端邻近节段退变发生率无统计学差异,而第2个近端邻近节段退变发生率具有统计学差异。末次随访时单边固定组和双边固定组的ODI评分分别为25.6±5.9、28.4±5.2,两组具有显著统计学差异(t=-2.503,P=0.014)。  结论:对于行腰椎后路减压融合术的单节段腰椎间盘突出症患者,单边固定者邻近节段退变发生率低于双边固定者,尤其对于第2个近端邻近退变节段的患者。%Background: In the instrumented fusion, adjacent facet joint violation or impingement by pedicle screws is unavoidable. Unilateral pedicle screw instrumentation is thought to reduce

  1. Clinical significance of MRI/{sup 18}F-FDG PET fusion imaging of the spinal cord in patients with cervical compressive myelopathy

    Energy Technology Data Exchange (ETDEWEB)

    Uchida, Kenzo; Nakajima, Hideaki; Watanabe, Shuji; Yoshida, Ai; Baba, Hisatoshi [University of Fukui, Department of Orthopaedics and Rehabilitation Medicine, Faculty of Medical Sciences, Eiheiji, Fukui (Japan); Okazawa, Hidehiko [University of Fukui, Department of Biomedical Imaging Research Center, Eiheiji, Fukui (Japan); Kimura, Hirohiko [University of Fukui, Departments of Radiology, Faculty of Medical Sciences, Eiheiji, Fukui (Japan); Kudo, Takashi [Nagasaki University, Department of Radioisotope Medicine, Atomic Bomb Disease and Hibakusha Medicine Unit, Atomic Bomb Disease Institute, Nagasaki (Japan)

    2012-10-15

    {sup 18}F-FDG PET is used to investigate the metabolic activity of neural tissue. MRI is used to visualize morphological changes, but the relationship between intramedullary signal changes and clinical outcome remains controversial. The present study was designed to evaluate the use of 3-D MRI/{sup 18}F-FDG PET fusion imaging for defining intramedullary signal changes on MRI scans and local glucose metabolic rate measured on {sup 18}F-FDG PET scans in relation to clinical outcome and prognosis. We studied 24 patients undergoing decompressive surgery for cervical compressive myelopathy. All patients underwent 3-D MRI and {sup 18}F-FDG PET before surgery. Quantitative analysis of intramedullary signal changes on MRI scans included calculation of the signal intensity ratio (SIR) as the ratio between the increased lesional signal intensity and the signal intensity at the level of the C7/T1 disc. Using an Advantage workstation, the same slices of cervical 3-D MRI and {sup 18}F-FDG PET images were fused. On the fused images, the maximal count of the lesion was adopted as the standardized uptake value (SUV{sub max}). In a similar manner to SIR, the SUV ratio (SUVR) was also calculated. Neurological assessment was conducted using the Japanese Orthopedic Association (JOA) scoring system for cervical myelopathy. The SIR on T1-weighted (T1-W) images, but not SIR on T2-W images, was significantly correlated with preoperative JOA score and postoperative neurological improvement. Lesion SUV{sub max} was significantly correlated with SIR on T1-W images, but not with SIR on T2-W images, and also with postoperative neurological outcome. The SUVR correlated better than SIR on T1-W images and lesion SUV{sub max} with neurological improvement. Longer symptom duration was correlated negatively with SIR on T1-W images, positively with SIR on T2-W images, and negatively with SUV{sub max}. Our results suggest that low-intensity signal on T1-W images, but not on T2-W images, is correlated

  2. Clinical significance of MRI/18F-FDG PET fusion imaging of the spinal cord in patients with cervical compressive myelopathy

    International Nuclear Information System (INIS)

    18F-FDG PET is used to investigate the metabolic activity of neural tissue. MRI is used to visualize morphological changes, but the relationship between intramedullary signal changes and clinical outcome remains controversial. The present study was designed to evaluate the use of 3-D MRI/18F-FDG PET fusion imaging for defining intramedullary signal changes on MRI scans and local glucose metabolic rate measured on 18F-FDG PET scans in relation to clinical outcome and prognosis. We studied 24 patients undergoing decompressive surgery for cervical compressive myelopathy. All patients underwent 3-D MRI and 18F-FDG PET before surgery. Quantitative analysis of intramedullary signal changes on MRI scans included calculation of the signal intensity ratio (SIR) as the ratio between the increased lesional signal intensity and the signal intensity at the level of the C7/T1 disc. Using an Advantage workstation, the same slices of cervical 3-D MRI and 18F-FDG PET images were fused. On the fused images, the maximal count of the lesion was adopted as the standardized uptake value (SUVmax). In a similar manner to SIR, the SUV ratio (SUVR) was also calculated. Neurological assessment was conducted using the Japanese Orthopedic Association (JOA) scoring system for cervical myelopathy. The SIR on T1-weighted (T1-W) images, but not SIR on T2-W images, was significantly correlated with preoperative JOA score and postoperative neurological improvement. Lesion SUVmax was significantly correlated with SIR on T1-W images, but not with SIR on T2-W images, and also with postoperative neurological outcome. The SUVR correlated better than SIR on T1-W images and lesion SUVmax with neurological improvement. Longer symptom duration was correlated negatively with SIR on T1-W images, positively with SIR on T2-W images, and negatively with SUVmax. Our results suggest that low-intensity signal on T1-W images, but not on T2-W images, is correlated with a poor postoperative neurological outcome. SUVmax

  3. 手术体位对高龄患者腰椎后路手术的影响%The effect and clinical outcome of prone and lateral position on the posterior lumbar inter-body fusion surgery in elderly patients

    Institute of Scientific and Technical Information of China (English)

    黎裕明; 王华; 戴海; 庞俊峰; 刘会江; 黄宗贵

    2016-01-01

    Objective To investigate the safety and clinical outcome of prone and lateral operation position for pa-tients older than 75 years with lumbar degenerative disc disease. Methods 65 patients with degenerative disease of lumbar spine who received posterior lumbar interbody fusion were enrolled,and randomly divided into prone group( n=30)and lateral positioning group(n=35). All patients underwent prone position or lateral position function training preoperatively. The medical record was reviewed to preoperative coexisting diseases, operative position tolerance, VAS and ODI in the pre-and post-operation, operative time, bleeding, partial pressure of CO2 ( PCO2 ) , wall-break-ing rate of pedicle screw placement, recovery time from anesthesia,excellent-good rate of one year postoperation, and so on. Results There were shorter operative time, less bleeding, lower PCO2 and shorter anesthesia recovery time in the lateral group(P0. 05). The pain VAS and ODI for body function im-proved significantly in the postoperation comparing with the preoperative in both groups(P0. 05 ) . All cases were followed up for one year. There was no significant differ-ence in the excellent-good rate of Macnab improved standard score between two groups ( P>0. 05 ) . Conclusions The lateral position can improve senile patients′ operative position tolerance, save operative time, reduce bleeding and postoperative PCO2 .%目的:探讨手术体位对高龄患者腰椎后路手术疗效的影响。方法对65例年龄≥75岁的腰椎退变性疾病患者行后路手术,随机抽签分为俯卧位组(30例)和侧卧位组(35例),患者术前均行俯卧位或侧卧位功能训练。记录患者术前并存疾病、手术体位耐受情况、手术前后腰腿痛VAS评分及ODI、手术时间、术中出血量、术中CO2分压、椎弓根钉置钉破壁率、术后麻醉复苏时间、术后1年疗效优良率。结果手术时间、术中出血量、术中CO2分压

  4. Clinical effects of minimally invasive transforaminal lumbar interbody fusion for obese ;patients with lumbar disc herniation in peri operation period%微创经椎间孔腰椎椎间融合术治疗腰椎间盘突出肥胖患者围手术期疗效评价

    Institute of Scientific and Technical Information of China (English)

    张权; 毛克亚; 王博; 顾挺帅; 熊森; 张雅宾; 韩振川; 王义国; 肖波

    2015-01-01

    of minimally invasive transforaminal lumbar interbody fusion (MIS‐TLIF) for the obese patients with lumbar disc herniation in peri operation period .Methods The retrospective analysis of 56 obese patients with lumbar disc herniation from January 2013 to June 2014 ,body mass index (BMI) of all patients was higher than 30 kg/m2 .There were 32 cases in MIS‐TLIF group and 24 cases in open transforaminal lumbar interbody fusion (Open‐TLIF) group . The average operation time ,intraoperative blood loss ,length of incision ,ambulation time ,hospitalization time ,blood indexes ,complication rate were compared between two groups . Japanese Orthopedic Association (JOA) score ,visual analogue scale (VAS) ,and Oswestry Dability Index (ODI) were assessed .Results The average operation time ,intraoperative blood loss ,length of incision ,ambulation time , hospitalization time ,complication rate were 200 .00 ± 43 .05 min ,420 .56 ± 86 .42 mL ,8 .00 ± 4 .01 cm ,100 .80 ± 53 .04 h ,9 .30 ± 3 .40 d and 8 .33% in Open‐TLIF group ,respectively .They were 120 .00 ± 28 .26 min ,110 .83 ± 50 .51 mL ,5 .00 ± 2 .52 d ,24 .37 ± 8 .50 h ,2 .50 ± 0 .18 cm and 6 .25% in MIS‐TLIF group ,respectively .There were significant differences between two groups (P 0 .05) .WBC , ESR and CRP in MIS‐TLIF group were significantly lower than those in Open‐TLIF group at 3 , 5 days postoperatively (P<0 .05) .JOA scores ,VAS scores and ODI in MIS‐TLIF group were better than those in Open‐TLIF group at 5 days postoperatively (P<0 .05) .The complication rate in MIS‐TLIF group was significantly lower than that in Open‐TLIF group (P<0 .05) .Conclusion MIS‐TLIF for the obese patients with lumbar disc herniation could have the advantages of less bleeding ,fewer complication rate ,shorter hospitalization time and quick recovery . It is the future trend of treatment for the obese patients with lumbar disc herniation .

  5. MICROSURGICAL LANDMARKS IN MINIMALLY INVASIVE TRANSFORAMINAL LUMBAR INTERBODY FUSION

    Directory of Open Access Journals (Sweden)

    Javier Quillo-Olvera

    2015-12-01

    Full Text Available Microsurgical landmarks of the facet joint complex were defined to provide guidance and security within the tubular retractor during transforaminal surgery. A retrospective observational study was performed in segments L4-L5 by the left side approach. Microsurgical relevant photos, anatomical models and drawing were used to expose the suggested landmarks. The MI-TLIF technique has advantages compared with conventional open TLIF technique, however minimally invasive technique implies lack of security for the surgeon due to the lack of defined microanatomical landmarks compared to open spine surgery, and disorientation within the tubular retractor, the reason why to have precise microsurgical references and its recognition within the surgical field provide speed and safety when performing minimally invasive technique.

  6. Spine surgery - discharge

    Science.gov (United States)

    ... Vertebral interbody fusion - discharge; Posterior spinal fusion - discharge; Arthrodesis - discharge; Anterior spinal fusion - discharge; Spine surgery - spinal fusion - discharge Images Spinal surgery -- cervical - series References Agrawal BM, Zeidman SM, Rhines L, ...

  7. Cervical dysplasia

    Science.gov (United States)

    ... by your provider. Make sure to get the HPV vaccine when it is offered to you. This vaccine prevents many cervical cancers. ... Early diagnosis and prompt treatment cures most cases of cervical ... severe cervical dysplasia may change into cervical cancer.

  8. Clinical effect of minimally invasive transforaminal lumbar interbody fusion combined with unilateral pedicle fixation on elderly lumbar degenerative diseases%微创经椎间孔椎间融合术并单侧椎弓根固定治疗老年人腰椎退变性疾病的临床疗效观察

    Institute of Scientific and Technical Information of China (English)

    张建乔; 曾忠友; 叶招明; 宋永兴; 韩建福; 籍剑飞

    2015-01-01

    Objective To analyze the clinical effect of minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) in combination with unilateral pedicle fixation on lumbar degenerative diseases in the elderly.Methods From June 2011 and June 2013,51 elderly patients with lumbar degenerative diseases who underwent MI-TLIF in combination with unilateral pedicle fixation,including 39 males and 12 females,aged from 60 to 72 years (average 65 years old),were included in this study.All the 51 cases had mono segmental lesion,including 11 cases with the lesion in L3.4,22 cases with the lesion in L4.5,and 18 cases with the lesion in L5-S1.The operation time,blood loss,postoperative drainage and complications were recorded.Postoperative outpatient follow-ups were conducted once every 2-3 months for all cases,and JOA scoring criteria (29 points) of lower back pain were adopted to evaluate the clinical effects.Thin-layer helical CT scanning reconstruction was applied to evaluate the fusion rate of bone grafting.X-ray film of lumbar vertebra AP & LAT was employed to evaluate the intervertebral space height,the internal fixation and the position of cage.Results The operation time ranged between 50-90 min with a mean value of 65 min; blood loss ranged between 80-180 ml (average 110 ml); and postoperative drainage volume ranged between 20-70 ml (average 40 ml).Healing phase I was achieved in 49 cases,while post-operative local cutaneous necrosis around the incision site occurred in 2 case and the wound healed well after wound dressing.Dural laceration without nerve root injury occurred in 2 cases.The follow up in 51 patients ranged between 18 24 months (average 20 months).In terms of JOA scoring,the preoperative score was (9.7± 1.6),the post operative score was (21.4 ± 1.4) 7 d after operation and the score was (25.4 ± 1.2) in the final follow up.During the final follow-up,35 cases were evaluated as excellent,11 cases as good and 5 cases as moderate,the excellent and good rate was

  9. Lateral Transpsoas Fusion: Indications and Outcomes

    Directory of Open Access Journals (Sweden)

    Vishal C. Patel

    2012-01-01

    Full Text Available Spinal fusion historically has been used extensively, and, recently, the lateral transpsoas approach to the thoracic and lumbar spine has become an increasingly common method to achieve fusion. Recent literature on this approach has elucidated its advantage over more traditional anterior and posterior approaches, which include a smaller tissue dissection, potentially lower blood loss, no need for an access surgeon, and a shorter hospital stay. Indications for the procedure have now expanded to include degenerative disc disease, spinal stenosis, degenerative scoliosis, nonunion, trauma, infection, and low-grade spondylolisthesis. Lateral interbody fusion has a similar if not lower rate of complications compared to traditional anterior and posterior approaches to interbody fusion. However, lateral interbody fusion has unique complications that include transient neurologic symptoms, motor deficits, and neural injuries that range from 1 to 60% in the literature. Additional studies are required to further evaluate and monitor the short- and long-term safety, efficacy, outcomes, and complications of lateral transpsoas procedures.

  10. 人工颈椎椎间盘置换与颈前路减压融合术治疗脊髓型颈椎病的疗效分析%Comparison of artifical cervical disc replacement versus anterior discectomy and fusion for the treatment of cervical spondylotic myelopathy

    Institute of Scientific and Technical Information of China (English)

    杨兴; 薛峰; 盛晓文; 彭育沁; 陈兵乾

    2012-01-01

    目的 比较人工颈椎椎间盘置换术与颈前路椎间盘切除减压植骨融合术(anterior cervical discectomy and fusion,ACDF)治疗脊髓型颈椎病的临床疗效.方法 回顾性分析本院收治的人工颈椎椎间盘置换术及ACDF治疗的脊髓型颈椎病病例.测量所有患者颈椎活动度(range of motion,ROM),置换节段及相邻节段的ROM,并行日本骨科学会(Japanese Orthopaedic Association,JOA)评分及Odom分级.结果 所有患者术后JOA评分和Odom功能评定均得到显著改善.置换组术后颈椎ROM、置换节段及其邻近间隙平均ROM无明显改变,差异无统计学意义(P>0.05).ACDF组患者中,术后颈椎ROM显著减小,邻近间隙ROM明显增大,差异有统计学意义(P<0.05).置换组术后邻近节段的ROM明显小于ACDF组,差异有统计学意义(P<0.01).结论人工颈椎椎间盘置换术能保持颈椎ROM,避免邻近节段退变,早、中期疗效满意,远期效果尚有待临床进一步研究.%Objective To compare the clinical outcome of artifical cervical disc replacement versus anterior cervical discectomy and fusion ( ACDF ) in the treatment of cervical spondylotic myelopathy. Methods A total of 50 cases of cervical spondylotic myelopathy treated by artifical cervical disc replacement ( n = 20 ) or ACDF ( n = 30 ) were involved. Among these cases , the range of motion ( ROM ) of the cervical vertebra, the implanted level and the adjacent segment were measured. The Japanese Orthopaedic Association ( JOA ) score and Odom' s grade were record and analyzed. Results All of these patients were followed-up, and JOA score and Odom' s grade of all patients were significantly improved. The ROM of the cervical vertebrae, the implanted levels and the adjacent segments were preserved in artifical cervical disc replacement group ( P >0. 05 ). In the ACDF group, the ROM of the cervical vertebrae decreased, but the adjacent segments of the fusion segment compensatory increased remarkably( P 0

  11. Multilevel decompressive laminectomy and transpedicular instrumented fusion for cervical spondylotic radiculopathy and myelopathy: A minimum follow-up of 3 years

    OpenAIRE

    Kadir Kotil; Emine Ozyuvaci

    2011-01-01

    Objective: Cervical laminectomies with transpedicular insertion technique is known to be a biomechanically stronger method in cervical pathologies. However, its frequency of use is low in the routine practice, as the pedicle is thin and risk of neurovascular damage is high. In this study, we emphasize the results of cervical laminectomies with transpedicular fixation using fluoroscopy in degenerative cervical spine disorder. Materials and Methods: Postoperative malposition of the transpedicul...

  12. Long-term outcome of laminectomy and instrumented fusion for cervical ossification of the posterior longitudinal ligament

    OpenAIRE

    Chen, Yu; Guo, Yongfei; Chen, Deyu; Wang, Xinwei; Lu, Xuhua; Yuan, Wen

    2008-01-01

    Between January 2000 and December 2003, a total of 83 patients (64 men and 19 women, average age: 56.4 years, range: 42–78 years) who underwent posterior laminectomy and instrumented fusion for ossification of the posterior longitudinal ligament (OPLL) were included in this study to investigate the long-term outcome of this surgical option and clarify which factors affect the prognosis. After an average 4.8-year follow-up, the mean Japanese Orthopaedic Association (JOA) score significantly in...

  13. Design of minimally invasive extraforaminal lumbar interbody fusion (ELIF) based on 3D printing technology%基于3D打印技术和微创腰椎椎间孔外椎体间融合术的设计

    Institute of Scientific and Technical Information of China (English)

    杨明杰; 李立钧; 潘杰; 郭松; 严浩然; 韩应超; 李泽清; 晏关俊; 曾诚

    2015-01-01

    目的 通过3D打印技术设计微创腰椎椎间孔外椎体间融合术(ELIF),探讨3D打印技术应用于临床研究的快速性和高效性.方法 通过对1名男性健康志愿者(26岁,身高172 cm,体质量67 kg)的腰椎行CT扫描,并采用MimicsV14.0软件进行三维重建,研究椎间孔区域骨性结构和神经结构的解剖关系.模拟切除上关节突,置入椎间融合器与椎弓根螺钉,最后通过3D打印技术得到实物进行验证,通过尸体标本验证ELIF的可行性. 结果 基于3D打印技术设计的ELIF的手术切口是正中线旁开6 cm的纵形手术切口,45°斜向椎体的手术通道,可以充分暴露伤椎的椎间孔区域.通过ELIF手术途径可充分显露目标椎间盘和神经根以及后方的上、下关节突和关节囊,操作简便、直观.ELIF手术可以实现单纯切除上关节突,保留下关节突,通过扩大的椎间孔牵开神经根后可以显露并切除椎间盘,并能完成椎间融合器的置入. 结论 通过3D打印技术设计的ELIF是一种创伤更小、安全、有效的腰椎椎体间融合术式.3D打印技术可以进行精确的手术设计,效率高、速度快、成本低、可操作性强,对真实手术有较好的指导作用.%Objective To design a new operation,extraforaminal lumbar interbody fusion (ELIF),with the help of 3D printing technology and to discuss the efficiency of using 3D printing technology in the clinical research.Methods A healthy male volunteer recruited for this study underwent CT scan of his lumbar vertebrae.He was 26 years old,172 cm in height and 67 kg in weight.Software Mimics V14.0 was used to read and reconstruct his CT scan data into 3D images.We observed the anatomical bone structures and nerve roots of the intervertebral foramen on 3D reconstruction images in Mimics to analyze the anatomic features of this area.The self-designed ELIF,pedicle screw insertion and cage placement were simulated via digital technology in Mimics.3D printing

  14. Fusão intersomática lombar transforaminal: experiência de uma instituição Fusión intersomática lumbar transforaminal: la experiencia de una institución Transforaminal lumbar interbody fusion: a single-center experience

    Directory of Open Access Journals (Sweden)

    Vinicius de Meldau Benites

    2012-12-01

    del dolor y/o claudicación neurogénicas en comparación con el status preoperatorio. Solamente cinco pacientes continuaron usando alguna medicación analgésica. Cinco pacientes presentaran alguna complicación, pero sólo dos de ellas están relacionadas directamente al procedimiento. CONCLUSIONES: Es una técnica segura, posible de ser realizada en todos los niveles de la columna lumbar y es aplicable a la mayoría de las enfermedades que afectan a esta región de la columna.OBJECTIVE: Describe the early results and experience from a reference center in spine surgery in São Paulo, Brazil with transforaminal lumbar interbody fusion (TLIF technique in its various indications. METHODS: We retrospectively reviewed the medical records of 25 patients who underwent surgery with TLIF technique in 2011. One patient was excluded because we considered that TLIF was not the most important technique used. The indications were 9 lumbar disc herniations, 7 spondylolistheses, 4 revision surgeries of which 2 were for pseudoarthroses and 2 for low back pain, and finally, 4 lumbar spinal stenoses. RESULTS: All the patients reported low back pain and/or neurologic claudication improvement when comparing to preoperative status. Only five patients continued using analgesics. Five patients presented some complication, but only two of them were related to the procedure. CONCLUSIONS: TLIF is a safe technique which can be performed at any lumbar level of the lumbar spine and is applicable to the majority of diseases that affect this region.

  15. A meta-analysis of clinical effects of Bryan cervical disc replacement versus anterior cervical discectomy and fusion%Bryan颈椎间盘置换与颈前路间盘切除植骨融合疗效的系统分析

    Institute of Scientific and Technical Information of China (English)

    李德毅; 张旭; 刘川; 吴继生

    2013-01-01

    BACKGROUND:Bryan cervical disc replacement and anterior cervical discectomy and fusion have a dispute in the treatment of cervical spondylosis. OBJECTIVE:To evaluate the clinical effects of Bryan cervical disc replacement and anterior cervical discectomy and fusion by meta-analysis, thereby providing clinical evidence for treatment strategy of cervical spondylosis. METHODS:The authors searched Medline, PubMed, EMBASE, OVID, CBM, CNKI and also searched manual y seven relevant Chinese orthopedic journals for articles pertinent to clinical research of Bryan cervical disc replacement and anterior cervical discectomy and fusion. Extracted data included the range of motion of the cervical spine, visual analog scale score, neck disability index, the Japanese Orthopaedic Association score. Meta-analysis and forest plots were conducted with RevMan4.2.2 Software. RESULTS AND CONCLUSION:There are eight articles in the meta-analysis, including 883 patients (430 patients receiving Bryan cervical disc replacement, and 453 patients receiving anterior cervical discectomy and fusion). Meta-analysis did detect statistical y significant differences in the range of motion of the cervical spine at 3 months and 24 months postoperatively between the two groups, but did not detect statistical y significant differences in visual analog scale score, neck disability index, the Japanese Orthopaedic Association score between the two groups. These findings indicate that Bryan cervical disc replacement is superior to anterior cervical discectomy and fusion in the range of motion of the cervical spine. However, the current literature offers no evidence to support superiority of the Bryan cervical disc replacement over the anterior cervical discectomy and fusion.%背景:Bryan颈椎间盘置换与颈前路间盘切除植骨融合治疗颈椎病的临床疗效存在争议。  目的:应用 Meta 分析方法,评价 Bryan 颈椎间盘置换与颈前路间盘切除植骨融合治疗颈椎病

  16. Three-level cervical disc herniation

    Directory of Open Access Journals (Sweden)

    St. Iencean Andrei

    2015-09-01

    Full Text Available Multilevel cervical degenerative disc disease is well known in the cervical spine pathology, with radicular syndromes or cervical myelopathy. One or two level cervical herniated disc is common in adult and multilevel cervical degenerative disc herniation is common in the elderly, with spinal stenosis, and have the same cause: the gradual degeneration of the disc. We report the case of a patient with two level cervical disc herniation (C4 – C5 and C5 – C6 treated by anterior cervical microdiscectomy both levels and fusion at C5 – C6; after five years the patient returned with left C7 radiculopathy and MRI provided the image of a left C6 – C7 disc herniation, he underwent an anterior microsurgical discectomy with rapid relief of symptoms. Three-level cervical herniated disc are rare in adults, and the anterior microdiscectomy with or without fusion solve this pathology.

  17. Five-year clinical results of cervical total disc replacement compared with anterior discectomy and fusion for treatment of 2-level symptomatic degenerative disc disease: a prospective, randomized, controlled, multicenter investigational device exemption clinical trial.

    Science.gov (United States)

    Radcliff, Kris; Coric, Domagoj; Albert, Todd

    2016-08-01

    OBJECTIVE The purpose of this study was to report the outcome of a study of 2-level cervical total disc replacement (Mobi-C) versus anterior cervical discectomy and fusion (ACDF). Although the long-term outcome of single-level disc replacement has been extensively described, there have not been previous reports of the 5-year outcome of 2-level cervical disc replacement. METHODS This study reports the 5-year results of a prospective, randomized US FDA investigational device exemption (IDE) study conducted at 24 centers in patients with 2-level, contiguous, cervical spondylosis. Clinical outcomes at up to 60 months were evaluated, including validated outcome measures, incidence of reoperation, and adverse events. The complete study data and methodology were critically reviewed by 3 independent surgeon authors without affiliation with the IDE study or financial or institutional bias toward the study sponsor. RESULTS A total of 225 patients received the Mobi-C cervical total disc replacement device and 105 patients received ACDF. The Mobi-C and ACDF follow-up rates were 90.7% and 86.7%, respectively (p = 0.39), at 60 months. There was significant improvement in all outcome scores relative to baseline at all time points. The Mobi-C patients had significantly more improvement than ACDF patients in terms of Neck Disability Index score, SF-12 Physical Component Summary, and overall satisfaction with treatment at 60 months. The reoperation rate was significantly lower with Mobi-C (4%) versus ACDF (16%). There were no significant differences in the adverse event rate between groups. CONCLUSIONS Both cervical total disc replacement and ACDF significantly improved general and disease-specific measures compared with baseline. However, there was significantly greater improvement in general and disease-specific outcome measures and a lower rate of reoperation in the 2-level disc replacement patients versus ACDF control patients. Clinical trial registration no. NCT00389597

  18. 前路减压植骨融合内固定术治疗颈椎间盘突出症的疗效分析%Analysis of anterior cervical decompression and autograft fusion combined with internal fixation in the treatment of cervical disc protrusion

    Institute of Scientific and Technical Information of China (English)

    杨朝晖; 吴险峰; 邹磊

    2013-01-01

    Objective To explore the clinical outcome of treatment of the anterior cervical discertomy and fusion with rigid plate fixation for cervical disc herniation. Methods Twenty five patients with cervical disc herniation had been treated by multilevel anterior cervical discectomy and fusion with rigid plate fixation from Oct 2008 to Oct 2011. Results All patients had been followed - up for 8 to 24 months ( I I months in average ). Bone union was achieved in all patients. All cases were scored after operation to assess the curative effect. There were 15 cases that belonged to the excellent, 8 to the good, 2 to the fair and 0 to the poor based on the Jndet criteria. The good and excellence rate was 92% in patients. Conclusion The treatment of traumatic cervical disc protrusion with anterior cervical decompression and bone autograft fusion combined with internal fixation has satisfactory clinical effect with fewer complications.%目的 探讨前路减压植骨融合钢板内固定治疗颈椎间盘突出症的疗效.方法 对收治的25例颈椎椎间盘突出症患者行颈椎前路减压,取自体髂骨植骨融合内固定治疗.结果 本组患者均获得随访,随访时间8~24个月,平均11个月.植骨均达到骨性愈合,无骨不连发生.25例患者神经功能获得改善,根据JOA神经功能评定标准,优15例,良8例,可2例,差0例,优良率92%.结论 颈椎前路减压、椎间盘切除、植骨融合钢板内固定是治疗颈椎间盘突出症的一种有效方法.

  19. 融合与非融合固定治疗脊髓型颈椎病:谁更易于椎体的活动度及稳定性?%Fusion and non-fusion fixation for cervical spondylotic myelopathy:which is more appropriate for maintaining range-of-motion and stability of vertebrae?

    Institute of Scientific and Technical Information of China (English)

    申超; 王文军; 晏怡果

    2014-01-01

    BACKGROUND:In recent years, many scholars adopted a joint non-fusion and fusion spinal fixation for multisegmental cervical spondylotic myelopathy, and achieved good clinical results. However, long-term clinical efficacy and possible related complications also require long-term fol ow-up of more in-depth study. OBJECTIVE:To review the research and application progress of anterior fusion and non-fusion fixation surgical operation for cervical myelopathy. METHODS:Computer-based search was conducted in China Journal Ful-text Database and PubMed database by the first author for articles related to anterior fusion and non-fusion fixation surgical operation for cervical myelopathy published between January 2004 and January 2014. The key words were“implant material;cervical spondylotic myelopathy;anterior;surgery;fusion;non-fusion;progress;hybrid;summary”in Chinese and“implant material;cervical spondylotic myelopathy;anterior;surgery/operation;fusion;non-fusion;research progress;hybrid;summary”in English. Final y, 35 articles were included for review. RESULTS AND CONCLUSION:Fusion and non-fusion fixation methods for cervical spondylotic myelopathy had their own advantages. From the view point of indications, the non-fusion fixation was relatively limited. Currently, the fusion fixation was stil the main method in treatment of cervical myelopathy. Non-fusion method as an emerging fixation method also achieved good short-period results, but it needs a long fol ow-up study. Hybrid fixation integrates the advantages of both methods, and can reduce the pressure. Simultaneously, Hybrid fixation also can reduce fusion segments, and retain the range-of-motion of the cervical spine as much as possible. Hybrid fixation becomes a hot topic in recent studies. However, most current researches on Hybrid fixation are retrospective study, lack of control. The overal fol ow-up time is short. Thus, Hybrid fixation needs to be researched more deeply.%背景:近年来,许多国

  20. CSF Leaks and Their Management Following Anterior Cervical Discectomy and Fusion: A Report of 13 Cases and a Review of the Literature.

    Science.gov (United States)

    Syre, Peter; Bohman, Leif-Erik; Baltuch, Gordon; Roux, Peter Le; Welch, William C

    2014-05-13

    : Study Design. Retrospective chart review and literature review.Objective. To identify cases where a CSF leak occurred during an ACDF and to create a management algorithm based on the findings.Summary of Background Data. Anterior cervical discectomy and fusion (ACDF) is a commonly performed spinal operation. It is effective with very low complication rates. One rare complication of ACDF is a CSF leak. There is limited information on the management of CSF leaks following ACDF and management is on a surgeon-by-surgeon basis.Methods. We reviewed 3 surgeons' case logs and identified cases where a CSF leak was encountered during ACDF and reviewed the patients' medical records, operative reports and imaging to determine how these leaks were managed. We also performed a PubMed search for articles about the presentation and management of CSF leaks following ACDF.Results. Thirteen CSF leaks were identified in 1223 ACDFs, corresponding to a CSF leak rate of 1%. Of these, 9 were successfully treated with intraoperative repair. Postoperative lumbar drainage was used in the remaining 4 patients and was successful in 1 patient. Three patients underwent neck re-exploration and attempted delayed repair. Three patients, including one who was found to have hydrocephalus, ultimately required continuous CSF diversion via shunting. We identified 7 case reports of CSF leak in ADCF in the literature and 1 article that reviewed the prevalence and management of this complication.Conclusion. CSF leak following ACDF is an uncommon complication that can usually be repaired. We provide a stepwise management strategy for CSF leaks in ACDF.

  1. MRI辅助髓核容积测定评价单侧椎弓螺钉置入并椎间融合对邻近节段的影响%MRI measurement of nucleus pulposus volume to assess the influence of unilateral pedicle screw fixation with an interbody fusion cage on adjacent segment

    Institute of Scientific and Technical Information of China (English)

    张红军; 王群波; 黄文强; 李波; 余雨; 邵高海

    2016-01-01

    隙高度均较治疗前略有减少,但差异无显著性意义(P>0.05)。⑤提示应用单侧单节段椎弓根螺钉置入内固定结合cage椎间植骨融合修复部分腰椎退性性疾病,可对固定融合邻近节段椎间盘退变起有一定的预防作用。%BACKGROUND:A large number of biomechanical studies and clinical application research showed that unilateral pedicle screw fixation with a single cage can not only make the spine to obtain immediate stability, and also reduces the fixed segment stiffness. However, there is not related research on the change of adjacent segment disc nucleus pulposus volume with unilateral pedicle screw. OBJECTIVE:To evaluate the effects of unilateral pedicle screw fixation with a single cage on adjacent segment degeneration for treating lumbar degenerative disease with MRI measurement of lumbar nucleus pulposus volume. METHODS:A total of 34 patients with lumbar disc herniation were treated by posterior lumbar interbody fusion with unilateral pedicle screw fixation with a single cage insertion. There were L4-5 segment in 16 patients (9 males and 7 females) and L5-S1segment in 18 patients (10 males and 8 females). The fixator was taken out at 18 months after surgery. They were folowed up for 24 to 36 months. With MRI, the transverse diameter and sagittal diameter of the nucleus pulposus were measured by using T2-weighted images at 6, 12, 18, 30 months after treatment, while the nucleus pulposus height was measured by middle sagittal position. Cephalic intervertebral height was measured with angular bisector method on X-ray films. Effects of unilateral pedicle screw fixation on cephalic intervertebral disc degeneration were evaluated according to nucleus pulposus volume and the intervertebral space height. RESULTS AND CONCLUSION:(1) Nucleus pulposus volume at cephalic L3-4 on the fixed L4-5segment was reduced in male patients after 30 months of treatment compared with pre-treatment (P=0.139), but increased in female

  2. Anterior cervical fusion and fixed system (Zero-P) for treating cervical spondylosis%新型颈椎前路椎间融合固定系统(Zero-P)治疗颈椎病的疗效分析

    Institute of Scientific and Technical Information of China (English)

    包肇华; 邹俊; 朱若夫; 吴春屾; 曹成

    2013-01-01

      背景:颈椎前路减压融合内固定术是治疗颈椎病的有效手段。但接骨板内固定在增加融合率的同时常导致一些并发症。  目的:探讨一种新型零切迹颈椎前路椎间融合固定系统(Zero-P)治疗颈椎病的疗效,以降低术后并发症的发生率。  方法:2010年6月至2011年6月对51例颈椎病患者行颈椎前路减压融合术。A组33例使用椎间融合器联合钛板固定;B组18例使用Zero-P。比较两组手术时间,术中出血量,JOA评分及改善率,NDI评分,术后融合率,术后并发症发生率。  结果:A组随访9~18个月,平均12个月;B组随访6~19个月,平均10个月。两组手术时间,术中出血量,JOA评分及改善率,NDI评分,融合率均无显著差异(P>0.05)。但B组术后并发症发生率明显低于A组(P  结论:Zero-P能降低术后并发症的发生率,尤其是吞咽不适的发生,是一种值得进一步临床应用的颈椎前路椎间融合固定系统。%Background: Anterior cervical discectomy and fusion (ACDF) is an effective treatment for cervical spondylosis. But inter-nal fixation with plate often results in some postoperative complications. Objective: To evaluate the clinical outcomes of a new anterior cervical fusion and fixed system (Zero-Profile) in the treat-ment of cervical spondylosis so as to decrease the postoperative complications. Methods: A total of 51 patients with cervical spondylosis were treated with ACDF between June 2010 and June 2011. Cage and titanium plate implantation were used in 33 patients of group A. Zero-Profile anterior cervical fusion and fixed system was applied in 18 patients of group B. Operation time, intraoperative blood loss, JOA and NDI scores, fusion rate and com-plications were compared between groups. Results: The mean follow-up period of group A was 12 months (range, 9 to 18 months). And the mean follow-up period of group B was10 months

  3. 颈椎前路融合与置换体外生物力学实验的新观点%Advances in research on anterior cervical fusion and replacement in vitro biomechanical experiment

    Institute of Scientific and Technical Information of China (English)

    吕聪伟; 蒲婷; 廖振华; 刘伟强

    2013-01-01

    背景:传统“金标准”颈前路减压植骨融合及近年来迅速发展的人工颈椎间盘置换是临床上常见的治疗颈椎病的方式。大量科研工作者和临床医生希望通过颈椎体外标本实验研究脊柱生物力学,为临床治疗提供指导数据。  目的:对现有颈椎体外标本生物力学实验研究进展进行综述,并对未来的研究方向进行展望。  方法:以“Cervical Spine, Fusion, Replacement, Hybrid, Biomechanics, In vitro, Adjacent-level Degeneration, Review”为英文检索词检索Pubmed数据库,以“颈椎,融合,置换,混合术,生物力学,体外,相邻节段退变,综述”为检索词检索CNKI数据库和万方数据库,检索2007年1月至2013年3月有关颈椎前路融合与置换体外生物力学实验研究进展的文献,主要整理近3年来相关研究,排除陈旧文章和重复性工作,最后对40篇文献进行归纳与讨论。  结果与结论:文章对现有的颈椎体外标本融合、置换实验进行总结,集中体现在手术多节段、运动控制条件差异化、颈椎耦合运动测试和新型植入器械4个方面,对比总结融合与置换治疗对邻近节段运动范围、关节内压力、髓核内压力和椎间孔形态的影响,探讨融合、置换后存在的问题。最后结合临床的需求,展望颈椎体外标本实验的发展趋势及应用前景。%BACKGROUND:Traditional“gold standard”of anterior cervical decompression with fusion and artificial cervical disc replacement rapidly developed in recent years are common clinical methods for the treatment of cervical spondylosis. A large number of researchers and clinicians hope to research the biomechanics of spine through cervical specimen in vitro experiments, which provide guidance for clinical surgery. OBJECTIVE:To review the cervical specimen in vitro experiments and to prospect the future research. METHODS:The PubMed database

  4. Clinical outcomes of selective anterior cervical corpectomy combined with segmental disectomy and fusion for treating three-level cervical myelopathy%前路选择性椎体切除结合单间隙减压植骨融合术治疗三节段脊髓型颈椎病的临床疗效

    Institute of Scientific and Technical Information of China (English)

    曹涌; 张烽; 陈向东; 姜星杰

    2011-01-01

    Objective To evaluate the clinical outcomes of selective anterior cervical corpectomy combined with segmental disectomy and fusion for treating three-level cervical myelopathy. Methods Thirtee patients of multilevel cervical myelopathy with 3 consecutive segments were treated with anterior cervical corpectomy combined with segmental disectomy and fusion. Study parameters included JOA score and grading the Odom criteria. The sagittal segmental alignment of fusion levels was measured using the Cobb method before and after surgery. Graft fusion rate was observed during final follow up. Results The patients were followed up for 12 to 39 months. The JOA score of 13 patients was higher three months after surgery than that before[(14. 6± 1.0) points vs. (11.1 ± 1.0) points] (P<0. 01). Surgical results of Odom criteria were excellent in 8 cases, good in 3 cases, fair in 2 cases. Graft fusion rate was 100%. Radiograph analysis indicated that the Cobb angle of mean segmental lordosis was 3.7 degrees before, 10.7 degrees one week later and 10.4 degrees during the final follow up. Conclusion Selective anterior cervical corpectomy combined with segmental disectomy and fusion results in high fusion rates with sufficient decompression in the treatment of three-level cervical myelopathy.%目的 分析颈前路选择性椎体次全切除十单间隙减压植骨融合术治疗三节段脊髓型颈椎病的临床疗效.方法 13例脊髓型颈椎病患者行颈前路选择性椎体次全切除十单间隙减压、自体髂骨植骨、钢板内固定术.分析术前及随访时的日本骨科协会(JOA)评分,记录术后Odom分级.测量术前、术后1周及末次随访时颈椎侧位X线片,观察术后颈椎植骨融合率、颈椎曲度(Cobb角)维持、症状及功能改善率.结果 13例患者随访12~39个月,术后3个月JOA评分为(14.6±1.0)分,明显高于术前的(11.1±1.0)分(P<0.01).术后Odom分级:优8例,良3例,一般2例,植骨融合率100%.

  5. 颈椎单节段融合术后相邻各节段运动补偿的规律研究%Research of the motion compensation after single segmental cervical spine fusion surgery

    Institute of Scientific and Technical Information of China (English)

    张睿; 周文钰; 顾洪生; 刘伟强; 白波; 王大平

    2014-01-01

    目的 了解颈椎单节段融合术后上、下相邻及非相邻节段的运动补偿规律.方法 通过三维运动采集系统,捕捉到6具新鲜人尸体颈椎单节段融合术前后C2~T1各节段的运动角度数据.结果 经过归一化处理后,分析得出颈椎单节段融合术后各节段的运动变化规律,发现融合术后其他各节段运动幅度均有不同程度的增加,尤其是下相邻节段,差异有统计学意义(P<0.05).结论 颈椎单节段融合术后邻近节段的代偿性运动幅度增加是导致其退变的重要原因.%Objective To know the motion compensation regulation of each segments after single segmental cervical spine fusion surgery.Methods With the help of 3D motion information collecting system,the movement angle of each segment was recorded before and after single segmental cervical spine fusion surgery.Results All the statistics are dealed with normalization,we got the statistics of the motion compensation regulation of each segments after single segmental cervical spine fusion surgery,range of motion of each segment increased diversely,especially the lower adjacent segment,with statistical significance(P<0.05).Conclusion Compensatory enhancement of the range of motion of adjacent segments is one of the important reasons lead to the degeneration.

  6. A Meta-analysis of Cervical Disc Arthroplasty Compared to Anterior Cervical Discectomy and Fu-sion for Degenerative Cervical Disc Disease%颈椎间盘置换与融合治疗退变性颈椎间盘疾病的 Meta 分析

    Institute of Scientific and Technical Information of China (English)

    石青鹏; 朱永林

    2016-01-01

    Objective To systematically compare the outcomes of cervical disc arthroplasty with anterior cervical discecto-my and fusion in the treatment of single-level degenerative cervical disc disease. Methods The references concerning cervical disc arthroplasty and anterior cervical discectomy and fusion for the singel-level degenerative cervical disc disease were re-trieved through PubMed,Cochrane Library,Ovid,SpringerLink,the China Biological Medicine Database,Wafang Database and Weipu Database,as well as by manually searching the related journals and literature. The eligible trials were extracted accord-ing to the inclusion and exclusion criteria. The methodological quality of the included trials were evaluated. RevMan5. 1 soft-ware was used for data analysis. Results Eight randomized controlled trials were included in the final Meta-analysis. The re-sults of Meta-analysis showed that statistically difference between these procedures in the SF-36(MD = 0. 98,95% CI:- 0. 33~ - 2. 29,Z = 1. 46,P = 0. 14),complications(OR = 0. 60,95% CI:0. 34 ~ 1. 04,P = 0. 07),reoperation rate(OR = 0. 52, 95% CI:0. 26 ~ 1. 05,Z = 1. 83,P = 0. 07). There were no statistically difference in the neck disability index(MD = - 2. 74, 95% CI:- 4. 57 ~ - 0. 91,Z = 2. 93,P = 0. 003),neck VAS(MD = - 2. 84,95% CI:- 4. 85 ~ - 0. 84,Z = 2. 78,P = 0. 005) and arm pain VAS(MD = - 1. 84,95% CI:- 3. 07 ~ - 0. 61,Z = 2. 92,P = 0. 003). Conclusion In treatment of single-level degenerative cervical disc disease,cervical disc arthroplasty has better outcomes in the improvement of pain symptom and neck function,but no superiority in complications,reoperation rate and SF-36 scores.%目的:系统性评价颈椎间盘置换与颈椎间盘摘除和融合治疗单节段退变性颈椎间盘疾病的效果。方法计算机检索 PubMed、Cochrane Library、Ovid、SpringerLink、中国生物医学文献数据库、万方、维普等数据库,手工检索相关杂志及纳入研究的参考文献,制

  7. Degenerative cervical myelopathy.

    Science.gov (United States)

    Kato, So; Fehlings, Michael

    2016-09-01

    Cervical myelopathy is the most common cause of acquired spinal cord compromise. The concept of degenerative cervical myelopathy (DCM), defined as symptomatic myelopathy associated with degenerative arthropathic changes in the spine axis, is being introduced. Given its progressive nature, treatment options have to be chosen in a timely manner. Surgical options include anterior discectomy and fusion (ACDF), anterior corpectomy and fusion (ACCF), arthroplasty (in highly select cases), posterior laminectomy with/without fusion, and laminoplasty. Indications for each should be carefully considered in individual patients. Riluzole, a sodium-glutamate antagonist, is a promising option to optimize neurologic outcomes post-surgery and is being examined in the CSM-Protect Randomized Controlled Trial. Preoperative risk assessment is mandatory for prognostication. Sagittal alignment is known to play an important role to optimize surgical outcome. Guidelines for optimal management of DCM are in process. In principle, all but the mildest cases of DCM should be offered surgery for optimal outcome. PMID:27250040

  8. Non-fusion segment disease after the anterior cervical arthrodesis:a retrospective study%颈椎前路融合术后非融合节段退变性疾病的回顾性研究

    Institute of Scientific and Technical Information of China (English)

    郭炳路; 宋科冉; 陈巧灵; 陈增海; 王大鹏; 王慧; 金培; 唐家广

    2016-01-01

    Objective To investigate the incidence and causes of non-fusion segment disease ( NFSD ), both adjacent and non-adjacent to the fused segment, after the anterior cervical arthrodesis.Methods This is a retrospective cohort study. Between January 1998 and January 2011, 171 patients who had anterior cervical decompression and fusion for the intervertebral disc herniation and cervical spondylosis were followed clinically. There were 97 males and 74 females, and the average age at the operation was ( 51.90 ± 9.28 ) years ( range: 31 - 72 years ). We evaluated the correlation between the incidence of symptomatic non-fusion segment disease and the following clinical parameters ( age at the operation, fusion levels ) and radiological parameters ( preoperative and postoperative cervical spine alignment, Pavlov’s ratio at the C5 level, and preoperative existence of a non-fusion segment degeneration on magnetic resonance imaging ).Results Of the 171 patients reviewed, 16 patients had non-fusion segment disease ( 9.36% ), 12 patients had adjacent segment disease and 4 had non-adjacent segment disease. Postoperative cervical lordosis in the non-fusion segment disease group was signiifcantly smaller than that of the disease-free group [ ( 7.38 ± 12.37 ) ° vs. ( 17.26 ± 9.75 ) °,P < 0.001 ]. Fusion levels in the NFSD group were 1.63 whereas 2.27 in disease-free group (P = 0.002 ). The incidence of disc degeneration in non-fused segments was more severe in the NFSD group than in the disease-free group [ ( 2.63 ± 0.62 )vs. ( 1.62 ± 0.99 ), P = 0.008 ].Conclusions The incidence of symptomatic non-fusion segment disease after the anterior cervical arthrodesis has multifactorial causes. Postoperative cervical lordosis, disc degeneration in non-fusion segments, and the number of fusion levels are all factors in the incidence of NFSD.%目的:探讨颈椎前路减压融合术后非融合节段病变( non-fusion segment disease,NFSD )的发生率和

  9. Biomechanical effects of polyaxial pedicle screw fixation on the lumbosacral segments with an anterior interbody cage support

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    Chen Hsiang-Ho

    2007-03-01

    Full Text Available Abstract Background Lumbosacral fusion is a relatively common procedure that is used in the management of an unstable spine. The anterior interbody cage has been involved to enhance the stability of a pedicle screw construct used at the lumbosacral junction. Biomechanical differences between polyaxial and monoaxial pedicle screws linked with various rod contours were investigated to analyze the respective effects on overall construct stiffness, cage strain, rod strain, and contact ratios at the vertebra-cage junction. Methods A synthetic model composed of two ultrahigh molecular weight polyethylene blocks was used with four titanium pedicle screws (two in each block and two rods fixation to build the spinal construct along with an anterior interbody cage support. For each pair of the construct fixed with polyaxial or monoaxial screws, the linked rods were set at four configurations to simulate 0°, 7°, 14°, and 21° lordosis on the sagittal plane, and a compressive load of 300 N was applied. Strain gauges were attached to the posterior surface of the cage and to the central area of the left connecting rod. Also, the contact area between the block and the cage was measured using prescale Fuji super low pressure film for compression, flexion, lateral bending and torsion tests. Results Our main findings in the experiments with an anterior interbody cage support are as follows: 1 large segmental lordosis can decrease the stiffness of monoaxial pedicle screws constructs; 2 polyaxial screws rather than monoaxial screws combined with the cage fixation provide higher compression and flexion stiffness in 21° segmental lordosis; 3 polyaxial screws enhance the contact surface of the cage in 21° segmental lordosis. Conclusion Polyaxial screws system used in conjunction with anterior cage support yields higher contact ratio, compression and flexion stiffness of spinal constructs than monoaxial screws system does in the same model when the spinal segment

  10. 颈椎间盘置换及前路椎间融合治疗单节段颈椎间盘突出症:谁更多影响邻近节段发生退变?%Anterior cervical disc replacement and anterior cervical decompression and fusion for treating single segment cervical disc herniation:which has greater effects on adjacent segment degeneration?

    Institute of Scientific and Technical Information of China (English)

    刘威; 盛伟斌; 张健; 邓强; 郭海龙

    2016-01-01

    背景:有研究表明,颈椎间盘置换及前路固定融合治疗颈椎病可以取得较好的临床效果,但是哪种术式在避免邻近节段退变方面更具优势尚无定论。目的:比较颈椎间盘置换与前路固定融合治疗单节段颈椎间盘突出症对邻近节段的近期影响。方法:收集2009年1月至2012年12月以“颈椎间盘突出症”为诊断收入院并行单节段颈椎间盘置换或颈前路椎间盘切除融合患者178例的临床资料,进行回顾性分析,其中前路固定融合组116例,颈椎间盘置换组62例。结果与结论:①评价:两组患者末次随访时目测类比评分、日本骨科协会评估治疗评分、颈椎功能障碍指数均较治疗前明显改善(P 0.05)。前路固定融合组术后3个月时手术节段基本融合,活动度丧失,末次随访时邻近上位节段活动度与邻近下位节段活动度明显增加,且上位节段活动度增加的度数较下位节段大(P 0.05). At 3 months after surgery, in the anterior cervical decompression and fusion group, surgical segment was confluent, and range of motion lost. During final fol ow-up, range of motion of adjacent upper segment and adjacent lower segment was significantly increased, and the increased range of motion in the upper segment was bigger than that of the lower segment (P < 0.05). (3) During final fol ow-up, X-ray films and MRI images revealed the number of degenerated adjacent segment was more in the anterior cervical decompression and fusion group than in the anterior cervical disc replacement group (P <0.05). The number of degenerated middle and upper segments was more than that of the lower segment in both groups (P < 0.05). (4) The findings confirmed that anterior cervical disc replacement or anterior cervical decompression and fusion for treating cervical disc herniation could effectively relieve nerve symptoms of patients. However, compared with the anterior cervical disc

  11. Outcome of instrumented spinal fusion for chronic low back pain: review of 100 patients

    International Nuclear Information System (INIS)

    Objective of this study was to evaluate the outcome of instrumented spinal fusion in selected patients with Chronic Low Back Pain (CLBP) in our setup. Consecutive first one hundred patients were selected from spine unit database that underwent instrumented spinal fusion for chronic low back pain lasting more than one year, due to degenerative disease of spine. Average age was 42 years. There were 62 males and 38 females. Diagnosis included; spinal stenosis (26%), failed disc surgery (22%), spondylolisthesis (19%), degenerative disc disease (17%), and instability (16%). Operations performed; Pedicle Screw Fixation (PSF) with Postero-lateral Fusion (PLF) in 3% patients. Trans Laminar Facet Screw (TLFS) with PLF in 24% patients. Anterior Lumbar Inter-body Fusion (ALIF) in 9% patients. Posterior Lumbar Inter-body Fusion (PLIF) in 40% patients and Trans-foraminal Lumbar Inter-body Fusion (TLIF) in 24% patients. Average follow up was for 30 months. 86% patients had full spinal fusion. 71% patients were fully satisfied with treatment, 28% were partially satisfied. Post-operatively, on average, visual analogue scale (VAS) showed 48 points significant improvement and Oswestry Disability Index (ODI) showed 53 points significant improvement. Instrumented Spinal Fusion is effective in our set up for relieving symptoms and improving functional outcome in selected patients with debilitating Chronic Low Back Pain due to degenerative disease of spine. Single fusion technique is not ideal for all types of patients and surgeon has to be versatile and trained in using different fusion techniques as the situation demands. (author)

  12. Segmental anterior cervical decompression with fusion for treating multilevel cervical myelopathy: Comparison of fusion rates among three methods%颈前路分节段减压植骨融合术治疗多节段颈椎病:3种方法移植骨融合率的比较

    Institute of Scientific and Technical Information of China (English)

    袁文; 徐盛明; 王新伟; 张涛; 刘百峰

    2007-01-01

    院时间均明显少于/短于长节段减压组(P<0.05),平均住院费用明显高于长节段减压组(P<0.05).分节段减压组、三间隙减压组和长节段减压组术后JOA评分提高分数和植骨融合率相近(P>0.05).结论:综合植骨融合率、神经功能恢复情况、手术时间、术中出血量、住院时间多种因素,3种术式中以颈前路分节段减压植骨融合术为治疗多节段颈椎病的手术方式较佳方案.%BACKGROUND:As a traditional treatment for multilevel cervical myelopathy,nterior long-segmental decompression has the shortcomings of great operative trauma,high difficulty,low fusion rate,etc.,which can affect the postoperative efficacy.OBJ ECTIVE:To evaluate the clinical effects of three different anterior surgeries on multilevel cervical myelopathy.DESIGN:A comparative observation.SETTING:Department of Orthopaedics,Changzheog Hospital,the Second Military Medical University of Chinese PLA.PARTICIPANTS:Thirty-six patients with multilevel cervical myelopathy of 3 consecutive segments,who were surgically treated,were selected from the Department of Orthopaedics,Changzheng Hospital,the Second Military Medical University of Chinese PLA from June 1999 to June 2003,including 25 males and 11 females,35-62 years of age,the disease course ranged from 3 to 26 months. According to the clinical manifestations and imaging esults,they were diagnosed as multilevel cervical myelopathy,and they were not suffering from consecutive ossification of posterior longitudinal ligament and ossification of ligamenta flava. Informed contents were obtained from all the patients and their relatives.METHODS:All the patients were grafted with utologous bone. Autologous ilium or cancellous bone excluding vertebral body was filled into titan net or Cage,which were made of titan and characterized by high intensity,tolerance to decay,good biocompatibility,etc. According to the operative manner,the patients were divided into 3 groups:① two

  13. Cervical Spondylotic Myelopathy: Factors in Choosing the Surgical Approach

    Directory of Open Access Journals (Sweden)

    Praveen K. Yalamanchili

    2012-01-01

    Full Text Available Cervical spondylotic myelopathy is a progressive disease and a common cause of acquired disability in the elderly. A variety of surgical interventions are available to halt or improve progression of the disease. Surgical options include anterior or posterior approaches with and without fusion. These include anterior cervical discectomy and fusion, anterior cervical corpectomy and fusion, cervical disc replacement, laminoplasty, laminectomy with and without fusion, and combined approaches. Recent investigation into the ideal approach has not found a clearly superior choice, but individual patient characteristics can guide treatment.</