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Sample records for cerebellopontine epidermoid presenting

  1. Epidermoid cyst causing hemifacial spasm epidermoid cyst in cerebellopontine angle presenting with hemifacial spasm

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    Murat Alemdar

    2012-01-01

    Full Text Available Hemifacial Spasm (HS occurs idiopathically or secondary to the lesions compressing the root exit zone of the facial nerve symptomatically. Symptomatic HS is generally due to vascular compression. We report on a 23-year-old male with right sided HS for a month. Magnetic resonance imaging (MRI of the brain revealed a well-demarcated epidermoid cyst in the right cerebellopontine cistern. It was hypointense on T1-weighted imaging, hyperintense on T2-weighted imaging without contrast enhancement, hyperintense on DWI, and slightly hypointense on ADC relative to the brain. Although it caused shifting of the pons and medulla to the left side and compression of the right cerebellar peduncles and fourth ventricle, the sole symptom of the patient was HS. Clinicians are advised to request MRI/scan for brainstem lesions from the patients with HS. Epidermoid cysts in cerebellopontine cistern may present with HS as the sole symptom.

  2. Epidermoid cyst in the cerebellopontine angle cistern presenting as trigeminal neuralgia

    International Nuclear Information System (INIS)

    This 29-year-old male had been suffering from left trigeminal neuralgia one year prior to admission. Admission was prompted by the development of pain in the third division of the left trigeminal nerve. Physical and neurological examinations were not remarkable except for the facial pain. The orbicularis oculi reflex showed delayed latency of R1 on the affected side. CT scans performed pre- and post-contrast enhancement revealed a low density area in the left cerebellopontine angle cistern. Metrizamide CT cisternography clearly revealed the margin of the lesion as the contrast media did not enter into the low density area. A left suboccipital craniectomy was performed. The trigeminal nerve was surrounded by a thin-capsulated mass and cholesteatoma materials. Histological diagnosis was epidermoid cyst. Since this surgical procedure, the trigeminal neuralgia has not recurred for one year. Without objective neurological deficits, it is difficult to distinguish symptomatic trigeminal from idiopathic neuralgia. Therefore, minor change of the orbicularis oculi reflex should help in objectively detecting dysfunction of the trigeminal nerve. Metrizamide CT cisternography is also useful in diagnosis of cystic lesions. (author)

  3. Epidermoid cyst in the cerebellopontine angle cistern presenting as trigeminal neuralgia. Diagnostic values of the orbicularis oculi reflex and metrizamide CT cisternography - case report -

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    Ueda, Takashi; Goya, Tomokazu; Kinoshita, Kazuo (Miyazaki Medical College, Miyazaki (Japan)); Fukui, Masashi

    1983-05-01

    This 29-year-old male had been suffering from left trigeminal neuralgia one year prior to admission. Admission was prompted by the development of pain in the third division of the left trigeminal nerve. Physical and neurological examinations were not remarkable except for the facial pain. The orbicularis oculi reflex showed delayed latency of R/sub 1/ on the affected side. CT scans performed pre- and post-contrast enhancement revealed a low density area in the left cerebellopontine angle cistern. Metrizamide CT cisternography clearly revealed the margin of the lesion as the contrast media did not enter into the low density area. A left suboccipital craniectomy was performed. The trigeminal nerve was surrounded by a thin-capsulated mass and cholesteatoma materials. Histological diagnosis was epidermoid cyst. Since this surgical procedure, the trigeminal neuralgia has not recurred for one year. Without objective neurological deficits, it is difficult to distinguish symptomatic trigeminal from idiopathic neuralgia. Therefore, minor change of the orbicularis oculi reflex should help in objectively detecting dysfunction of the trigeminal nerve. Metrizamide CT cisternography is also useful in diagnosis of cystic lesions.

  4. Cerebellopontine angle epidermoid showing a positive enhancement upon metrizamide CT cisternography

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    Hasegawa, Takeshi; Wakamatsu, Koichi; Fujii, Toshiharu; Ito, Haruhide; Yamamoto, Shinjiro; Nagata, Izumi

    1985-04-01

    A case of epidermoid tumor in the left cerebellopontine angle cistern is reported in a 43-year-old woman with left trigeminal neuralgia. Plain CT scan revealed a low density area at the left cerebellopontine angle and left ambient cisterns, which could not be differentiated from their enlargement. Metrizamide CT cisternography showed an irregular, high density pattern in the low density filling defect which was extending into the suprasellar and interpeduncular cisterns. The developmental mechanism of this specific finding in the metrizamide CT cisternography was discussed on the basis of morphological characteristics of epidermoid tumor.

  5. Cerebellar glioblastoma multiforme presenting as a cerebellopontine angle mass

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    Anupam Jindal

    2006-01-01

    Full Text Available Cerebellar glioblastoma multiforme (GBM is a highly malignant brain tumour, which is exceedingly rare and such tumour presenting as cerebellopontine angle (CPA mass is even rarer. We here discuss the case of a 15-year-old girl who had cerebellar GBM presenting as CPA mass that resembled meningioma on CT scan and was managed successfully with minimal problems.

  6. Arteriovenous malformation in the cerebellopontine angle presenting as trigeminal neuralgia

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    Paulo C. Figueiredo

    1989-03-01

    Full Text Available A case of arteriovenous malformation of the left cerebellopontine angle causing symptoms of ipsilateral trigeminal neuralgia is reported. Pain relief followed microsurgical removal of the malformation. The authors review the literature on the subject.

  7. Malignant Transformation Six Months after Removal of Intracranial Epidermoid Cyst: A Case Report

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    Fayçal Lakhdar

    2011-01-01

    Full Text Available Intracranial epidermoid cysts are uncommon benign tumors of developmental origin; malignant transformation of benign epidermoid cysts is rare, and their prognosis remains poor. We report a case of squamous cell carcinoma arising in the cerebellopontine angle. A 52-year-old man presented with left facial paralysis and cerebellar ataxia. He had undergone total removal of a benign epidermoid cyst six months previously. Postoperative magnetic resonance imaging of the brain revealed a heterogeneous and cystic lesion in the left cerebellopontine angle with hydrocephalus. The cyst wall was enhanced by gadolinium. He underwent ventricle-peritoneal shunt and removal again; the histopathological examination revealed a squamous cell carcinoma possibly arising from an underlying epidermoid cyst. This entity is being reported for its rarity. The presence of contrast enhancement at the site of an epidermoid cyst combined with an acute, progressive neurological deficit should alert the neurosurgeon to the possibility of a malignant transformation.

  8. Facial nerve neurinoma presenting as middle cranial fossa and cerebellopontine angle mass : a case report.

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    Devi B

    2000-10-01

    Full Text Available Facial nerve neurinomas are rare. The tumours arising from the geniculate ganglion may grow anteriorly and superiorly and present as a mass in the middle cranial fossa. Only a few cases of facial nerve neurinomas presenting as middle cranial fossa mass have so far been reported. These tumours present with either long standing or intermittent facial palsy along with cerebellopontine angle syndrome.

  9. Clinical presentation of intracranial epidermoids: a surgical series of 20 initial and four recurred cases

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    Kato, Koichi; Ujiie, Hiroshi; Higa, Takashi; Hayashi, Masataka; Kubo, Osami; Okada, Yoshikazu; HORI, TOMOKATSU

    2010-01-01

    Epidermoids are generally recognized as benign tumors; however, total resection is often difficult. The recurrence from the residual capsule, dissemination of the tumor, and aseptic meningitis are common problems. The aim of the present study was to analyze and report on the clinical characteristics of intracranial epidermoids, particularly complications and cases with a poor clinical outcome. 24 patients with intracranial epidermoids who were treated surgically at Tokyo Women's Medical Unive...

  10. Trigeminal Neuralgia Caused by Pontocerebellar Angle Epidermoid Tumor: A Case Report and Review of Literature

    OpenAIRE

    Muhammet Bahadır Yılmaz; Semra Yılmaz; Ayhan Tekiner

    2015-01-01

    Trigeminal neuralgia (TN) is the most commonly seen craniofacial pain syndrome. Etiology of TN can be divided into classical (idiopathic and vascular compression) and symptomatic (tumor, demyelinating, and ischemic) types. Especially, symptomatic trigeminal neuralgia is seen with tumors located in the cerebellopontine angle. Epidermoid tumors comprise about 1% of all brain tumors and 5% of tumors located in the cerebellopontine angle. These tumors may present with trigeminal neuralgia due to ...

  11. Unilateral vocal cord palsy and dysphagia: an unusual presentation of cerebellopontine angle meningioma.

    Science.gov (United States)

    Senior, Andrew; Douglas, James Andrew; Thompson, Stuart

    2015-01-01

    Cerebellopontine angle (CPA) tumours are the most common neoplasms in the posterior fossa, accounting for 5-10% of intracranial tumours. Most CPA tumours are benign, with most being vestibular schwannomas. Meningiomas arising from the jugular foramen are among the rarest of all with very few being described in the literature. Treatment options vary considerably as experience with these tumours is limited. One option is a skull base approach, but this depends on size, location and ability to preserve lower cranial nerve function. This can be extremely challenging and is accompanied by high mortality risk; therefore, a more conservative option must be considered. This case report highlights the difficulty in management of patients with jugular fossa meningiomas, including appropriate investigations, analysis of surgical versus conservative treatment and associated complications. Furthermore, we elaborate the decision-making process pertaining to the tailoring of the surgical route used for the resection of jugular foramen meningiomas. (Jugular Foramen Meningioma, cerebellopontine angle). PMID:26486157

  12. Epidermoid Carcinoma of the Cervix and Pregnancy. A case presentation.

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    Práxedes Rojas Quintana

    2007-12-01

    Full Text Available A 25 year-old female patient with a 12 week pregnancy was presented. She was diagnosed with an ultered Pap test. She was referred to the cervix uterine pathology specialist where an exophytic lesion compatible to cervix uterine cancer in advanced stages. The treatment as well as the conduct followed by the specialist was really hard due to the patient´s pregnant condition.

  13. Urgent penectomy in a patient presenting with epidermoid carcinoma of the penis associated to myiasis

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    Antonio J. Tavares; Rodrigo Barros; Luciano A. Favorito

    2007-01-01

    The objective of this study is to describe the case of a patient presenting advanced epidermoid carcinoma of the penis associated to myiasis. A 41-year-old patient presenting with a necrotic lesion of the distal third of the penis infested with myiasis was attended in the emergency room of our hospital and was submitted to an urgent penectomy. This is the first case of penile cancer associated to myiasis described in the literature. This case reinforces the need for educative campaigns to red...

  14. Urgent penectomy in a patient presenting with epidermoid carcinoma of the penis associated to myiasis

    Directory of Open Access Journals (Sweden)

    Antonio J. Tavares

    2007-08-01

    Full Text Available The objective of this study is to describe the case of a patient presenting advanced epidermoid carcinoma of the penis associated to myiasis. A 41-year-old patient presenting with a necrotic lesion of the distal third of the penis infested with myiasis was attended in the emergency room of our hospital and was submitted to an urgent penectomy. This is the first case of penile cancer associated to myiasis described in the literature. This case reinforces the need for educative campaigns to reduce the incidence of this disease in developing countries.

  15. Epidermoid cyst post dermofasciectomy.

    LENUS (Irish Health Repository)

    Henry, Francis P

    2010-01-01

    We report the finding of an unusual presentation of an epidermoid cyst 3 years following dermofasciectomy for Dupuytren\\'s disease. Epidermoid cysts remain a rare entity in the palmoplanter distribution but also a very unusual finding within the confines of a full thickness skin graft.

  16. Cerebellopontine angle Hodgkin's disease

    International Nuclear Information System (INIS)

    Intracranial Hodgkin's disease is a rare site of involvement, and even more rare is its presentation as a cerebellopontine angle mass. It can be difficult to diagnose especially when recurrent tumors occur because both CT and lumbar puncture have been shown to have a relatively low yield. Gadolinium-enhanced MRI is more sensitive. It is concluded that while the imaging findings can be non-specific, the rapid response to therapy (steroids) may provide a clue to diagnosis. Copyright (1999) Blackwell Science Pty Ltd

  17. Bilateral Testicular Epidermoid Cysts

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    Norman Loberant; Shweta Bhatt; Edward Messing; Dogra, Vikram S.

    2011-01-01

    Testicular epidermoid cysts are the most common benign tumors of the testes, but account for only 1-2% of all testicular tumors. In a young man presenting with a testicular mass, a high index of suspicion must be maintained for the malignant testicular germ cell tumor, which is 50-times more common than testicular epidermoid cyst. Bilateral testicular epidermoid cysts are a very rare condition, with only a few reports in the literature. It is extremely important in this condition to make a co...

  18. Disorders of the cerebellopontine angle

    International Nuclear Information System (INIS)

    Disorders of the cerebellopontine angle may present by symptoms like vertigo, hearing problems, affection of the trigeminal or facial nerve. Ipsilateral ataxia and contralateral hemiparesis develop in case of a rather large tumor in this region and display an involvement of the cerebellum and/or brainstem. However, some of these typical symptoms are not recognized by the patient. Thus, in case of a suspicion of a disorder of the cerebellopontine angle the relevant functions have to be tested clinically. In addition, electrophysiology can confirm dysfunction of these cranial nerves. Mainstay of the therapy should be the treatment of the underlying cause. Nevertheless, not seldom it is necessary to treat symptoms like vertigo or facial pain. (orig.)

  19. Cerebellopontine Choroid Plexus Papilloma: Case Report

    International Nuclear Information System (INIS)

    We present the case of an adult female patient who presented with a mass in the cerebellopontine angle, corresponding to a choroid plexus papilloma. Due to this uncommon location, we report this case and describe its imaging characteristics and the possible differential diagnoses.

  20. High-density intracranial epidermoid tumors

    International Nuclear Information System (INIS)

    An intracranial epidermoid tumor appears as a low-density lesion on CT. This is a report on 3 cases of high-density intracranial epidermoids, which had been regarded as rare. In Case 1, one continuous tumor was noted in the bilateral cerebellopontine regions. A CT scan showed homogeneous high-density zones in the bilateral cerebellopontine-angle regions, with high-density spots indicating calcifications in the prepontine region. In Case 2, the tumor existed around the medulla and in the upper cervical spinal canal; it also seemed embedded in the pons. This tumor appeared on CT as a homogeneous high-density mass. In Case 3, the tumor was thought to have originated from Meckel's cave and to extend mainly into the extradural space in the middle fossa and in the subdural space in the posterior fossa on the right. On CT, this tumor seemed to be a dumbbell-shaped, inhomogeneous high-density mass which contained some low-density areas and peripheral high-density spots indicating calcifications. An obvious contrast enhancement was noted along the margin of the tumor. In each case, dark brown contents, indicating the existence of blood components, were obtained by surgery. These blood components are assumed to be the cause of the high density on CT. Moreover, in Case 3, the microscopic findings of operated-on specimens showed intramural hemorrhage. There were neovascularities in the cyst wall due to the organization of the blood components. It was considered that the blood components in the cystic cavity were the result of a dissection of the intramural hemorrhage. The extravasation of the contrast material from the neovascularities into the extracellular space of the cyst wall was considered to be a main cause of the contrast enhancement in Case 3. Also shown was a characteristic pattern of the extension of epidermoids, a pattern which was revealed by reviewing the reported cases of epidermoids and our own cases. (author)

  1. Differentiated nasosinusal epidermoid carcinoma

    International Nuclear Information System (INIS)

    Two case reports of young patients, who were treated in the Otolaryngology Department from 'Dr. Joaquin Castillo Duany' Teaching Clinical Surgical Hospital in Santiago de Cuba are presented. One of the cases presented nasal obstruction, rhinorrhoea and facial pain, for 7 months; the other one presented an increase of volume in the right ocular globe. In both, the results of the biopsy confirmed the diagnosis of differentiated nasosinusal epidermoid carcinoma

  2. A case of right cerebellopontine-angle lesion: psychotic symptoms and magnetic resonance imaging findings.

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    Jung, Min Soo; Lee, Byung Dae; Park, Je Min; Lee, Young Min; Moon, Eun Soo

    2012-09-01

    Here, we report psychotic symptoms together with a right cerebellopontine-angle lesion. A37-year-old female patient presented with a trigeminal Schwannoma occupying the right cerebellopontine angle. Her psychotic symptoms included auditory hallucinations and delusions of persecution. T1- and T2-weighted images on magnetic resonance imaging (MRI) revealed hyperintense and hypointense areas in the right cerebellopontine angle, respectively. The clinical and neuroimaging reviews in this case suggest that sudden onset of psychotic symptoms at a mature age may be associated with a right cerebellopontine-angle lesion and that MRI should be used to evaluate possible organic bases in patients that present with psychosis. PMID:22993532

  3. Epidermoid cyst of the posterior fossa: a case report Cisto epidermoide da fossa posterior: relato de caso

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    Eduardo Cambruzzi

    2011-02-01

    Full Text Available Epidermoid cysts of the central nervous system are uncommon conditions, which are frequently located in the cerebellopontine angle and around the pons. They are covered with keratinized squamous epithelium and keratin lamella, which give its contents a soft, white-pearly appearance. Epidermoid cysts are mostly originated from malformations, presumably associated with surface elements of the nervous system ectoderm during the closure of the neural groove or formation of secondary cerebral vesicles. The authors describe a case of epidermoid cyst in the posterior fossa causing hydrocephalus and review morphologic and diagnostic criteria of this lesion.Os cistos epidermoides do sistema nervoso central (SNC são condições incomuns, estando localizados mais frequentemente no ângulo pontocerebelar e ao redor da ponte. Eles são revestidos por epitélio escamoso queratinizado e lamelas de queratina, tornando seu conteúdo branco-perolado e pastoso. Os cistos epidermoides são, na maioria das vezes, originados de malformações, possivelmente associados ao entremeio de elementos superficiais do ectoderma do SNC durante o fechamento da placa neural, ou formação das vesículas cerebrais secundárias. Os autores descrevem um caso de cisto epidermoide da fossa posterior determinando hidrocefalia e revisam critérios morfológicos e diagnósticos dessa lesão.

  4. Intraosseous Epidermoid Cyst Associated with Impacted Mandibular Wisdom Teeth: An Uncommon Entity

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    Toptas, Orcun; Akkas, Ismail; TEK, Mustafa; Ozan, Fatih; Boran, Cetin

    2014-01-01

    Epidermoid and dermoid cysts of the jaws are seen rarely. The formation theories of the intraosseous epidermoid cyst (IEC) are not clear. The radiographic appearance is similar with unilocular cysts. Surgical enucleation is the suggested treatment method for epidermoid cysts. This case report presents bilateral mandibular intraosseous epidermoid cysts with impacted wisdom teeth which is the first documented case in the literature.

  5. Concomitant bilateral testicular epidermoid cysts

    International Nuclear Information System (INIS)

    Epidermoid cyst of the testis is a rare benign germ tumor, comprising 1-2% of all resected benign testicular masses. Approximately 300 cases have been reported to date. Unilateral involvement has often been reported in the English literature. However, bilateral occurrence is very rare and to the best of our knowledge, there only 3 previous reports of bilateral testicular epidermoid cysts. The fact that they are completely benign makes them amenable to treatment by local excision, thereby saving patient from orchidectomy. Recognition of their characteristic ulatrsonographic features is very important to avoid unnecessary intervention. We present here, a case of bilateral epidermoid cyst in which characteristic ultrasound (US) findings allowed testis-sparing enucleation instead of radical orchiectomy. (author)

  6. [Giant intradiploic infratentorial epidermoid cyst].

    Science.gov (United States)

    Alberione, F; Caire, F; Fischer-Lokou, D; Gueye, M; Moreau, J J

    2007-10-01

    Epidermoid cysts are benign, uncommon lesions (1% of all intracranial tumors). Their localization is intradiploic in 25% of cases, and exceptionally subtentorial. We report here a rare case of giant intradiploic infratentorial epidermoid cyst. A 74-year old patient presented with recent diplopia and sindrome cerebellar. CT scan and MR imaging revealed a giant osteolytic extradural lesion of the posterior fossa (5.2 cm x 3.8 cm) with a small area of peripheral enhancement after contrast injection. Retrosigmoid suboccipital craniectomy allowed a satisfactory removal of the tumor, followed by an acrylic cranioplasty. The outcome was good. Neuropathological examination confirmed an epidermoid cyst. We review the literature and discuss our case. PMID:18008017

  7. Epidermoid Carcinoma of the Cervix and Pregnancy. A case presentation. Carcinoma epidermoide de cuello uterino y embarazo. Presentación de un caso.

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    Doris González Díaz

    Full Text Available

    A 25 year-old female patient with a 12 week pregnancy was presented. She was diagnosed with an ultered Pap test. She was referred to the cervix uterine pathology specialist where an exophytic lesion compatible to cervix uterine cancer in advanced stages. The treatment as well as the conduct followed by the specialist was really hard due to the patient´s pregnant condition.

    Se presenta el caso de una paciente de 25 años, con un embarazo de 12 semanas a la que se le diagnosticó una citología alterada, y que al remitirse a la consulta de patología de cuello uterino se observó una lesión exofítica compatible con un cáncer de cuello en estadio avanzado. El tratamiento y la conducta seguida fueron difíciles debido al embarazo.

     

  8. Epidermoid Cyst of the Testicle: Unusual Magnetic Resonance Imaging Findings

    International Nuclear Information System (INIS)

    Epidermoid cyst of the testis is an uncommon benign tumor that can be treated by organ-preserving surgery when diagnosed preoperatively. Although some sonographic characteristics may be suggestive of epidermoid cysts, sonography is not completely diagnostic. Magnetic resonance imaging (MRI) findings may provide support for the diagnosis of epidermoid cysts. The MRI findings of testicular epidermoid cysts have been reported as either bull's eye or target in appearance, or with signal intensity characteristics more typical of a cystic lesion. In this paper, we present typical sonographic and unusual MRI findings of a testicular epidermoid cyst

  9. Recurrent intramedullary epidermoid cyst of conus medullaris.

    LENUS (Irish Health Repository)

    Fleming, Christina

    2011-01-01

    Spinal intramedullary epidermoid cyst is a rare condition. Recurrent epidermoid cyst in the spine cord is known to occur. The authors describe a case of recurrent conus medullaris epidermoid cyst in a 24-year-old female. She initially presented at 7 years of age with bladder disturbance in the form of diurnal enuresis and recurrent urinary tract infection. MRI lumbar spine revealed a 4 cm conus medullaris epidermoid cyst. Since the initial presentation, the cyst had recurred seven times in the same location and she underwent surgical intervention in the form of exploration and debulking. This benign condition, owing to its anatomical location, has posed a surgical and overall management challenge. This occurrence is better managed in a tertiary-care centre requiring multi-disciplinary treatment approach.

  10. Recurrent Perianal Sinus in Young Girl Due To Pre-sacral Epidermoid Cyst

    OpenAIRE

    Jain, V.; Misra, S; Tiwari, S; Rahul, K; Jain, H.

    2013-01-01

    Pre-sacral epidermoid cysts are rare development cysts resulting from dysembryogenesis mostly diagnosed in middle aged women. We report a case of pre-sacral epidermoid cyst presenting with recurrent perianal sinus in young girl. Generally pre-sacral epidermoid cysts are seen in adult age group but it is rare presentation in young age group. We report a rare case of presacral epidermoid cyst occurring in a young female.

  11. Epidermoid cyst of the ovay in young woman: A case report

    International Nuclear Information System (INIS)

    In general, ovarian epidermoid cysts coexist with surface epithelial ovarian tumors. Pure epidermoid cysts are extremely rare diseases, comprising less than 1% of surface ovarian tumors. We present here a pathologically proven epidermoid cyst of the ovary in a young woman with ultrasonographic and magnetic resonance findings

  12. Epidermoid cyst of the ovay in young woman: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Jung Hee; Kim, See Hyung; Kang, Yu Na; Kim, Mi Jeong [Keimyung University School of Medicine, Dongsan Medical Center, Daegu (Korea, Republic of)

    2015-06-15

    In general, ovarian epidermoid cysts coexist with surface epithelial ovarian tumors. Pure epidermoid cysts are extremely rare diseases, comprising less than 1% of surface ovarian tumors. We present here a pathologically proven epidermoid cyst of the ovary in a young woman with ultrasonographic and magnetic resonance findings.

  13. Traumatic Acute Subdural Hematoma Extending from the Posterior Cranial Fossa to the Cerebellopontine Angle

    OpenAIRE

    Gulsen, Salih; Sonmez, Erkin; Yilmaz, Cem; Altinors, Nur

    2009-01-01

    Posterior cranial fossa subdural hematomas and extension of the subdural hematoma to the cerebellopontine angle is rarely seen and the concurrent development of acute peripheral facial palsy and the management strategy have not previously been reported in this pathology because of its rarity. We present this case to emphasize that minor head trauma may lead to a posterior cranial fossa hematoma extending to the cerebellopontine angle and cause peripheral facial palsy in patients using aspirin...

  14. Extensive Epidermoid Cyst and Breathing Difficulty

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    Ciro Dantas Soares

    2015-01-01

    Full Text Available Epidermoid cysts are common cystic lesions in the skin, ovaries, and testicles, but their occurrence in the oral cavity is uncommon. They consist of cysts delimited by a fibrous capsule without cutaneous annexes and are lined by stratified squamous epithelium. The differential diagnosis includes ranula, dermoid cysts, and lingual thyroid. Despite their benign presentation, these cysts can cause functional limitations, requiring special clinical attention for extensive lesions located in regions that preserve vital structures. This paper aims to report a case of epidermoid cyst in patient with swallowing and breathing difficulty, highlighting the clinical and surgical planning.

  15. Epidermoid cyst of clitoris mimicking clitoromegaly

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    Aggarwal Satish

    2010-01-01

    Full Text Available Clitoromegaly in pediatric and adolescent age group is usually indicative of a disorder of sexual differentiation. We report a girl child presenting with clitoral enlargement due to an epidermoid cyst. The cyst was excised with complete cosmetic recovery.

  16. Cytodiagnosis of epidermoid cyst of the upper lip: A common lesion in an uncommon site

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    Jyoti Prakash Phukan; Anuradha Sinha; Subrata Pal; Shilpa Jalan

    2014-01-01

    Epidermoid cyst and dermoid cysts are developmental pathologies thought to derive from aberrant ectodermal tissue. They are uncommon in the head and neck region. Rarely, they can be found in the oral cavity and buccal mucosa. However, epidermoid cyst is extremely uncommon in the upper lip and is rarely reported. In this study, we report an uncommon case of epidermoid cyst occurring in the upper lip diagnosed by fine-needle aspiration cytology (FNAC). We present this case because of its extrem...

  17. Malignant melanoma of the cerebello-pontine angle region

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    F. Menezes Braga

    1989-12-01

    Full Text Available A case of malignant melanoma in the cerebello-pontine angle region is presented in a 72 years old female patient, who had neurological examination and CT scan suggestive of acoustic neuroma. The surgical finding and the histological examination provided the diagnosis. As a primary focus was not found on clinical examination and although autopsy was not carried out, there is a possibility of the diagnosis being a primary malignant melanoma in CNS. This specific location for this kind of tumor was found to be rare when literature is looked up.

  18. Disorders of the cerebellopontine angle; Klinik der Kleinhirnbrueckenwinkelerkrankungen

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    Block, F. [Helios-Kliniken Schwerin (Germany). Neurologische Klinik

    2006-03-15

    Disorders of the cerebellopontine angle may present by symptoms like vertigo, hearing problems, affection of the trigeminal or facial nerve. Ipsilateral ataxia and contralateral hemiparesis develop in case of a rather large tumor in this region and display an involvement of the cerebellum and/or brainstem. However, some of these typical symptoms are not recognized by the patient. Thus, in case of a suspicion of a disorder of the cerebellopontine angle the relevant functions have to be tested clinically. In addition, electrophysiology can confirm dysfunction of these cranial nerves. Mainstay of the therapy should be the treatment of the underlying cause. Nevertheless, not seldom it is necessary to treat symptoms like vertigo or facial pain. (orig.) [German] Schwindel, Hoerstoerungen, Affektionen des N. trigeminus oder des N. facialis stellen die wesentlichen und haeufigen Symptome bei Kleinhirnbrueckenwinkelerkrankungen dar. Ipsilaterale Gliedmassenataxie und kontralaterale Hemiparese sprechen fuer eine Mitbeteiligung von Kleinhirn und/oder Hirnstamm, die meist nur bei grossen Prozessen in dieser Region auftreten. Da einige Veraenderungen sich fuer den Patienten unbemerkt entwickeln, ist bei Verdacht eine gezielte klinische Untersuchung dieser Funktionen angezeigt, die durch elektrophysiologische Diagnostik wie z. B. akustisch evozierte Potenziale oder Blinkreflexe untermauert werden kann. Auch wenn natuerlich die kausale Therapie im Vordergrund steht, ist es gar nicht selten notwendig, eine symptomatische Behandlung durchzufuehren. Dies trifft besonders fuer Symptome wie Schwindel oder Gesichtsschmerzen zu. (orig.)

  19. Resection of large recurrent third ventricular epidermoid tumors through the posterior interhemispheric transcallosal approach.

    Science.gov (United States)

    Hendricks, Benjamin K; Cohen-Gadol, Aaron A

    2016-01-01

    Epidermoid cysts or tumors comprise 1% of intracranial tumors with a predilection for the cerebellopontine angle or parasellar cisterns. These tumors are derived from an ectopic ectodermal implant seeded between fusing ectodermal surfaces. This results in a benign proliferation of stratified squamous epithelium along a cyst wall with a lumen composed of hyperkeratotic material derived from the desquamating cells. Surgical intervention is the treatment of choice for symptomatic patients. There is no role for radiotherapy or chemotherapy in the treatment of these lesions, including for residual or recurrent disease. The inherent adhesion of the proliferating epithelial lining to surrounding neurovascular structures significantly complicates attempts at gross-total resection. Epidermoid tumors or cysts are rarely reported within the third ventricular region. In this video, the authors demonstrate the technique of right-sided posterior interhemispheric transcallosal approach for maximal resection of a complex recurrent third ventricular epidermoid tumor with lateral ventricular extension. The video can be found here: https://youtu.be/wbXp7mc0vT4 . PMID:26722690

  20. Imaging of cerebellopontine angle lesions: an update. Part 2: intra-axial lesions, skull base lesions that may invade the CPA region, and non-enhancing extra-axial lesions

    Energy Technology Data Exchange (ETDEWEB)

    Bonneville, Fabrice; Chiras, Jacques [Pitie-Salpetriere Hospital, Department of Neuroradiology, Paris (France); Savatovsky, Julien [Adolphe de Rothschild Foundation, Department of Radiology, Paris (France)

    2007-11-15

    Computed tomography (CT) and magnetic resonance (MR) imaging reliably demonstrate typical features of vestibular schwannomas or meningiomas in the vast majority of mass lesions responsible for cerebellopontine angle (CPA) syndrome. However, a large variety of unusual lesions can also be encountered in the CPA. Covering the entire spectrum of lesions potentially found in the CPA, these articles explain the pertinent neuroimaging features that radiologists need to know to make clinically relevant diagnoses in these cases, including data from diffusion- and perfusion-weighted imaging or MR spectroscopy, when available. A diagnostic algorithm based on the lesion's site of origin, shape and margins, density, signal intensity and contrast material uptake is also proposed. Non-enhancing extra-axial CPA masses are cystic (epidermoid cyst, arachnoid cyst, neurenteric cyst) or contain fat (dermoid cyst, lipoma). Tumours can also extend into the CPA by extension from the skull base (paraganglioma, chondromatous tumours, chordoma, cholesterol granuloma, endolymphatic sac tumour). Finally, brain stem or ventricular tumours can present with a significant exophytic component in the CPA that may be difficult to differentiate from an extra-axial lesion (lymphoma, hemangioblastoma, choroid plexus papilloma, ependymoma, glioma, medulloblastoma, dysembryoplastic neuroepithelial tumour). (orig.)

  1. Neuronavigation assisted decompression of trigeminal neuralgia caused by cerebellopontine angle osteoma

    OpenAIRE

    Iimura Yasushi; Saitou Rikizou; Abe Kazuhiro; Tsunoda Akira; Maruki Chikashi; Arai Hajime

    2014-01-01

    Trigeminal neuralgia (TN) is usually caused by vascular compression of the trigeminal nerve root entry zone, but can be caused by other factors such as tumors, vascular disorders, and demyelination in multiple sclerosis. We present a rare case with a huge osteoma located on the cerebellopontine angle (CPA) and causing TN. A 48-year-old woman presented with TN caused by a huge left CPA bone tumor. Surgery was performed by the lateral suboccipital approach under neuronavigation system guidance ...

  2. Large and small cells non-keratinizing epidermoid vaginal carcinoma

    International Nuclear Information System (INIS)

    Five case reports of patients who were assisted at the cervix Pathology Department from 'Mariana Grajales Coello' Provincial Gynecological Obstetrical Hospital in Santiago de Cuba due to vaginal bleeding, low abdominal pain, leukorrhea and vaginal injuries are presented. The pathological study confirmed the diagnosis of squamous or epidermoid cells carcinoma

  3. Cytodiagnosis of epidermoid cyst of the upper lip: A common lesion in an uncommon site

    Directory of Open Access Journals (Sweden)

    Jyoti Prakash Phukan

    2014-01-01

    Full Text Available Epidermoid cyst and dermoid cysts are developmental pathologies thought to derive from aberrant ectodermal tissue. They are uncommon in the head and neck region. Rarely, they can be found in the oral cavity and buccal mucosa. However, epidermoid cyst is extremely uncommon in the upper lip and is rarely reported. In this study, we report an uncommon case of epidermoid cyst occurring in the upper lip diagnosed by fine-needle aspiration cytology (FNAC. We present this case because of its extremely rare site of presentation and also to highlight the role of FNAC to in the pre-operative diagnosis of this benign lesion.

  4. Dorsal intramedullary spinal epidermoid cysts: Report of two cases and review of literature

    Directory of Open Access Journals (Sweden)

    Cincu Rafael

    2007-01-01

    Full Text Available Intramedullary epidermoid cysts of the spinal cord are rare tumors, especially those not associated with spinal dysraphism. About 50 cases have been reported in the literature. Of these, only seven cases have had magnetic resonance imaging (MRI studies. We report two cases of spinal intramedullary epidermoid cysts with MR imaging. Both were not associated with spina bifida. In one patient, the tumor was located at D4 vertebral level; while in the other, within the conus medullaris. The clinical features, MRI characteristics and surgical treatment of intramedullary epidermoid cyst are presented with relevant review of the literature.

  5. Epidermoid cyst of the floor of the mouth. A case report and literature review

    Directory of Open Access Journals (Sweden)

    Rojas-Madrigal A

    2012-02-01

    Full Text Available Dermoid and epidermoid cysts are cystic benign, slightly common malformations that may be found in the area of head and neck between 1.6 and 7 %, representing less than 0.01 % of all the cysts of the oral cavity. This pathology is important of the knowledge of the professional in dentistry and medicine to be able to do the early diagnose and the respective treatment. The purpose of this study is the review of the relevant literature of the dermoid and epidermoid cysts and the presentation of a case of epidermoid cyst in floor of mouth in a patient of 13 years and 5 months of age.

  6. Epidermoid cyst of the coronal sulcus mimicking penile cancer: a case report

    OpenAIRE

    Cormio, Luigi; Mancini, Vito; Sanguedolce, Francesca; Massenio, Paolo; Fucci, Livia; Bufo, Pantaleo; Traficante, Antonio; Carrieri, Giuseppe

    2014-01-01

    Introduction Epidermoid cysts represent common benign tumors occurring anywhere in the body but very rarely in the penis. Only a few cases of penile localization have been reported in the literature so far, most of them being congenital and/or idiopathic, usually presenting in children as slow-growing, solitary, well-delimited cystic lesions. Here, we describe the case of a patient with a penile epidermoid cyst presenting as an ulcerated lesion of the coronal sulcus, thus mimicking penile can...

  7. Computed tomography and magnetic resonance imaging of acquired abnormalities of the inner ear and cerebello-pontine angle

    International Nuclear Information System (INIS)

    CT and MRI of acquired abnormalities of the inner ear and cerebello-pontine angle present themselves with very typical findings. The imaging should be adapted to the pathology looked for and either CT or MRI should be used alone or in combination.CT, especially high resolution CT (HRCT), provides an excellent bone contrast, while MRI has a much superior soft tissue contrast. Acute inflammatory changes of the inner ear are solely depicted by contrast-enhanced MRI. HRCT excellently depicts osseous changes of the inner ear and cerebellopontine angle such as chronic ossifying labyrinthitis occurring after acute labyrinthitis, otosclerotic or traumatic changes. Tumorous changes not yielding to bony changes are best delineated by MRI. Posttraumatic hemorrhage and chronic fibrotic changes within the labyrinth are depicted by MRI, only. In conclusion HRCT and MRI are excellent methods to delineate acquired abnormalities of the inner ear and cerebello-pontine angle. HRCT best depicts osseous changes while MRI best depicts soft tissue changes. HRCT and MRI are not concurrent methods but should better be used as complementary methods for imaging acquired abnormalities of inner ear and cerebellopontine angle. (orig.)

  8. Differentiation between pediatric spinal arachnoid and epidermoid-dermoid cysts: is diffusion-weighted MRI useful?

    International Nuclear Information System (INIS)

    Appropriate differentiation between epidermoid-dermoid and arachnoid cysts is important for patient management. MRI has had limitations in differentiating these two types of cysts, especially in the region of the spinal cord. To evaluate the role of diffusion-weighted (DW) MRI for differentiation between spinal arachnoid and epidermoid-dermoid cysts. Four children underwent conventional and DW MRI. Turbo spin-echo imaging was used to obtain DW images. On conventional MRI, low T1-W and high T2-W signal was present in all lesions. DW imaging showed restricted diffusion in two patients with epidermoid-dermoid cysts and no water restriction in two patients with arachnoid cysts. Three of four children had extramedullary lesions and one patient had an intramedullary lesion. Three children had surgery, two with epidermoid-dermoid cysts and one with arachnoid cyst. Diagnosis was confirmed by histopathology. One child with a thoracic arachnoid cyst had stable clinical imaging findings during a follow-up of 21 months. On conventional MRI, epidermoid-dermoid and arachnoid cysts have similar signal characteristics. Initial experience with spine DW imaging shows promise in differentiating epidermoid-dermoid cysts from arachnoid cysts. Preoperative differentiation is important because it changes management and surgical approach. (orig.)

  9. Differentiation between pediatric spinal arachnoid and epidermoid-dermoid cysts: is diffusion-weighted MRI useful?

    Energy Technology Data Exchange (ETDEWEB)

    Kukreja, Kamlesh [Miami Children' s Hospital, Department of Radiology, Miami, FL (United States); Manzano, Glen; Ragheb, John [Miami Children' s Hospital and University of Miami, Department of Neurological Surgery, Miami, FL (United States); Santiago Medina, L. [Miami Children' s Hospital, Health Outcomes, Policy and Economics (HOPE) Center, Department of Radiology, Miami, FL (United States)

    2007-06-15

    Appropriate differentiation between epidermoid-dermoid and arachnoid cysts is important for patient management. MRI has had limitations in differentiating these two types of cysts, especially in the region of the spinal cord. To evaluate the role of diffusion-weighted (DW) MRI for differentiation between spinal arachnoid and epidermoid-dermoid cysts. Four children underwent conventional and DW MRI. Turbo spin-echo imaging was used to obtain DW images. On conventional MRI, low T1-W and high T2-W signal was present in all lesions. DW imaging showed restricted diffusion in two patients with epidermoid-dermoid cysts and no water restriction in two patients with arachnoid cysts. Three of four children had extramedullary lesions and one patient had an intramedullary lesion. Three children had surgery, two with epidermoid-dermoid cysts and one with arachnoid cyst. Diagnosis was confirmed by histopathology. One child with a thoracic arachnoid cyst had stable clinical imaging findings during a follow-up of 21 months. On conventional MRI, epidermoid-dermoid and arachnoid cysts have similar signal characteristics. Initial experience with spine DW imaging shows promise in differentiating epidermoid-dermoid cysts from arachnoid cysts. Preoperative differentiation is important because it changes management and surgical approach. (orig.)

  10. Intraosseous epidermoid cysts in the distal phalanx of two dogs

    International Nuclear Information System (INIS)

    Two dogs were presented with a history of lameness associated with swelling of one of the digits. Radiographs of the affected digits revealed an irregularly mineralized, smoothly marginated proliferative bone lesion in the distal phalanx of one dog and a destructive bony lesion in the distal phalanx of the second dog. The differential diagnosis included nail bed carcinoma, malignant melanoma, osteomyelitis, and subungual keratoacanthoma. Radiographic findings and no response to medical treatment resulted in amputation and submission of the digits for a histopathologic diagnosis. Histologic examination of the distal phalanx of the digits revealed benign epidermoid cysts associated with either bony proliferation or osteolysis. Excision of the lesions was curative. This report presents the clinical, radiographic, and histopathologic findings associated with intraosseous epidermoid cysts in the distal phalanx of two dogs

  11. Contrast-enhanced CISS imaging of cerebellopontine angle tumors

    Energy Technology Data Exchange (ETDEWEB)

    Tozaki, Mitsuhiro; Toyoda, Keiko; Hata, Yuichi; Fukuda, Yasushi; Fukuda, Kunihiko [Jikei Univ., Tokyo (Japan). School of Medicine; Katano, Shuichi

    1999-10-01

    Our purpose of this study was to evaluate the clinical usefulness of contrast-enhanced CISS-3DFT MR imaging for the diagnosis of CP angle tumors. CISS-3DFT MR imaging is expected for screening procedure of acoustic schwannoma because of excellent spatial resolution. Recently, we discovered contrast enhancement effect on CISS sequence in spite of heavily T{sub 2}-weighted images. Fourteen patients with CP angle tumors were performed on a 1.0 T MR unit. Transaxial CISS-3DFT MRI was obtained both before and after intravenous injections of Gd-DTPA. Multiplanar reconstructions (MPRs) were performed in all cases. Contrast enhancement effect of CP angle tumors, and the relationship between tumors and the adjacent cranial nerves were evaluated. Contrast enhancement effect of the tumors was present in all cases in spite of heavily T{sub 2}-weighted images of CISS sequences. In the internal auditory canal, relationship between the tumors and the cranial nerves was demonstrated in 6 cases (6/9). In the cerebellopontine cistern, all cases were demonstrated (11/11). Contrast-enhanced CISS-3DFT MR imaging with a good contrast resolution and an excellent spatial resolution is useful for the diagnosis of CP angle tumors. (author)

  12. Treatment of epidermoid tumors with gamma knife radiosurgery: Case series

    OpenAIRE

    Javier A Jacobo Vasquez; Julio R Fonnegra; Juan C Diez; Andres Fonnegra

    2016-01-01

    Background: Epidermoid tumors (ETs) are benign lesions that are treated mainly by means of surgical resection, with overall good results. External beam radiotherapy is an alternative treatment for those recurrent tumors, in which a second surgery might not be the best choice for the patient. A little information exists about the effectiveness of gamma knife radiosurgery for the treatment of newly diagnosed and recurrent ETs. We present three cases of ETs treated with gamma knife radiosurgery....

  13. Orbital dermoid and epidermoid cysts: Case study

    OpenAIRE

    Veselinović Dragan; Krasić Dragan; Stefanović Ivan; Veselinović Aleksandar; Radovanović Zoran; Kostić Aleksandar; Cvetanović Marija

    2010-01-01

    Introduction. Dermoid and epidermoid cysts of the orbit belong to choristomas, tumours that originate from the aberrant primordial tissue. Clinically, they manifest as cystic movable formations mostly localized in the upper temporal quadrant of the orbit. They are described as both superficial and deep formations with most frequently slow intermittent growth. Apart from aesthetic effects, during their growth, dermoid and epidermoid cysts can cause disturbances in the eye motility, and i...

  14. Choroid plexus papilloma of cerebellopontine angle with extension to foramen magnum.

    Directory of Open Access Journals (Sweden)

    Kumar R

    1999-01-01

    Full Text Available A case of choroid plexus papilloma resembling meningioma of cerebellopontine (CP angle with its extension to foramen magnum is presented. Occurrence of this tumour in CP angle is very rare. Its extension towards foramen magnum is further rare. It was a real diagnostic enigma preoperatively as the tumour was resembling meningioma upto some extent on radiological study. Retromastoid craniectomy with microsurgical excision of tumour and its extension was achieved in toto. Tumour was attached to few rootlets of lower cranial nerves which were preserved. Attachment of the tumour with lower cranial nerves again caused diagnostic confusion with neurofibroma intraoperatively.

  15. CT and MR imaging of acquired abnormalities of the inner ear and cerebellopontine angle

    International Nuclear Information System (INIS)

    Introduction: Several entities of acquired lesions may affect the inner ear and cerebellopontine angle. The imaging of these lesions depends on the clinical history, and should be adapted to the lesion searched for and suspected by the otolaryngologist. In this paper, the modality of CT and MR imaging which is suited to delineate the acquired lesions of this region will be presented. Materials and methods: CT and/or MR imaging of the inner ear and cerebellopontine angle was performed in all cases in which an acquired lesion of this region was suspected by the otolaryngologist. CT was performed in the axial and coronal plane with the use of a high-resolution bone-window-level-setting. MRI was performed in the axial plane using high-resolution 3D T2-weighted fast spin echo sequences and 3D T1-weighted gradient echo sequences before and after the i.v. application of gadopentate dimeglumine. The obtained images were evaluated for the depiction of the acquired lesions. Results: CT best depicted osseous lesions such as traumatic affections or lesions leading to ossification of the inner ear. Tumorous lesions were delineated in those cases in which they yielded to bony changes. Inflammatory or tumorous lesions not yielding to bony changes or intralabyrintine calicifications were not depicted. MRI delineated very well all lesions leading to soft tissue changes, and moderately depicted traumatic changes yielding to less severe fractures affecting the investigated region. Conclusion: CT and MR imaging are suited differently to delineate the acquired lesions of the inner ear and cerebellopontine angle. CT is excellently suited to depict osseous lesions, while MRI is excellently suited to delineate lesions affecting the soft tissue structures. These two imaging modalities should be used depending on the clinical question, and are supposed to be complementary methods

  16. Unusual Cases of Epidermoid cyst: Case Series

    Directory of Open Access Journals (Sweden)

    Lalita Yadav

    2013-09-01

    Full Text Available In the oro-facial region cystic lesions of different etiologies are encountered owing to the presence of the teeth in the jaw bones. A bewildering variety of developmental, odontogenic and non-odontogenic cysts are seen. Epidermoid cyst is a rare developmental cyst of the oro-facial region which results from entrapped epidermal elements without adnexal appendages. Dermoid and epidermoid cysts occur in oro-facial region with an incidence of 6.9-7% and represents less than 0.01% of all oral cavity cysts. Here we report two cases of epidermoid cysts occurring at unusual locations involving upper left maxillary region lateral to the nose and pinna of the ear.

  17. Unusual Cases of Epidermoid cyst: Case Series

    OpenAIRE

    Lalita Yadav; Geetpriya Kaur; Naveen Puri; Varun Rastogi; Rachna Sharma

    2013-01-01

    In the oro-facial region cystic lesions of different etiologies are encountered owing to the presence of the teeth in the jaw bones. A bewildering variety of developmental, odontogenic and non-odontogenic cysts are seen. Epidermoid cyst is a rare developmental cyst of the oro-facial region which results from entrapped epidermal elements without adnexal appendages. Dermoid and epidermoid cysts occur in oro-facial region with an incidence of 6.9-7% and represents less than 0.01% of all oral cav...

  18. MRI of the cerebellopontine angle in patients with cleido-cranial dysostosis

    International Nuclear Information System (INIS)

    Purpose: Cleidocranial dysostosis (CCD) is an autosomal dominant bone disorder in which deafness is common secondary to malformation of the middle ear structures. The study aimed at MRI evaluation of the cerebellopontine angle in 7 patients with a history of CCD - two generation spanned relatives. Material and methods: Cranial MRI in 7 patients with CCD (4 women/3 men aged between 8 and 46 years) was performed. In two patients hearing disorders were present. The examinations encompassed multi-planar spinecho sequences of the cerebellopontine angle in 3-mm slice thickness before and after administration of contrast medium. Results: The clinically most conspicuous female patient (hearing loss, ataxia, headache) showed a strongly contrast-enhancing tumor in MRI that was histologically proved to be an acoustic schwannoma. Concerning the other family members, no pathological findings were noted except for non-pneumatized mastoids. Conclusion: The first report of a patient with CCD and an acoustic schwannoma shows that in case of hearing loss in these patients also a retrocochlear cause must be considered. (orig.)

  19. Primary intradural sacral epidermoid in a nondysraphic spine: Case report and review of literature

    Science.gov (United States)

    Sivaraju, Laxminadh; Thakar, Sumit; Ghosal, Nandita; Hegde, Alangar S

    2016-01-01

    The occurrence of epidermoids within the spinal canal is uncommon. Most of the reported spinal epidermoids (SEs) have been described in the thoracic or lumbar regions. They occur either following trauma or in the setting of coexistent spinal dysraphism. The authors describe an unusual case of a 28-year-old lady who presented with long-standing back pain and urinary incontinence. Magnetic resonance imaging (MRI) of her spine demonstrated a sacral SE without any coexistent spinal dysraphism. The diagnosis of an epidermoid was confirmed by histopathological examination following laminectomy and excision. To the authors’ best knowledge, this is the third case of a sacral SE occurring in a non-dysraphic spine. The case is discussed in the light of a relevant literature review.

  20. Intracortical epidermoid cyst of the tibia

    International Nuclear Information System (INIS)

    Epidermoid cyst in a long bone is an extremely rare condition. The authors describe such a tumor located in the cortex of the tibia in a 21-year-old woman. She was successfully treated with curettage and autogenous bone grafting. (orig.)

  1. Leech therapy for epidermoid cysts and review of the literature

    OpenAIRE

    Abbas Rasi; Alireza Faghihi; Mirhadi Aziz Jalali; Abbas Zamanian; Gholamhossein Ghaffarpour

    2014-01-01

    Hirudo medicinalis sucks blood directly through the external mammalian skin. We recently observed a healthy 64-year-old Iranian man, who presented with numerous asymptomatic multilobular oval-to-round well-defined 0.5 to 1.5 cm cystic lesions with central umbilication (central black eschar) over the upper portion of his chest. We made the diagnosis of epidermoid cyst, giant comedone and leech bite on the basis of the constellation of clinical features. The patient was treated with oral ciprof...

  2. Ganglioneuroma of the Internal Auditory Canal Presenting as a Vestibular Schwannoma

    OpenAIRE

    Bekelis, Kimon; Meiklejohn, Duncan A; Missios, Symeon; Harris, Brent; Saunders, James E; Erkmen, Kadir

    2011-01-01

    In most series, 90% of cerebellopontine angle tumors are vestibular schwannomas. Meningiomas and epidermoid tumors follow with decreased frequency. Ganglioneuroma is a benign tumor usually found in the retroperitoneum and posterior mediastinum. We report a case of a 21-year-old man with gradual sensorineural hearing loss and a minimally enhancing lesion of the internal auditory canal, which was excised through a middle fossa approach and found histologically to be a ganglioneuroma. Like vesti...

  3. Epidermoid cyst of the testis: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Docal, I.; Crespo, C.; Pardo, A.; Prieto, A.; Alonso, P. [Servicio de Radiologia, Hospital Da Costa, Burela (Lugo) (Spain); Calzada, J. [Servicio de Anatomia Patologica, Hospital Da Costa, Burela (Lugo) (Spain)

    2001-05-01

    Epidermoid cyst of the testis is an uncommon benign tumour, with an overall incidence of 1-2 % of all resected testicular masses. When imaging findings suggest that an intratesticular mass is likely to be an epidermoid cyst, conservative management (enucleation with testicular preservation) can be performed rather than orchidectomy. This case report records an epidermoid cyst in a 12-year-old boy in whom the US findings allowed testis-sparing surgery instead of orchidectomy. (orig.)

  4. An uncommon case of lymphoplasmacytic lymphoma in cerebellopontine angle region: Case report with a literature review.

    Science.gov (United States)

    Yan, Chengrui; Kong, Xiangyi; Yang, Lanshu; Ma, Wenbin

    2016-08-01

    In the central nervous system, cerebellopontine angle (CPA) lymphomas are rare; few cases have been reported. Lymphoplasmacytic lymphoma (LPL) in the CPA is rarer still, and often misdiagnosed as acoustic neuroma.We report a rare case of CPA LPL-a challenging diagnosis guided by clinical presentations, radiological signs, and postoperative pathological test.A 43-year-old woman presented with headaches. Her magnetic resonance imaging revealed an abnormal homogeneously enhancing mass in the left CPA. We present detailed analysis of her disease and review relevant literature.When surgically treated, her specimen showed a typical LPL histopathology pattern. After surgery, the patient's symptoms improved greatly, and she received chemotherapy.Despite its rarity, LPL should be considered in differential diagnoses of CPA lesions that mimic acoustic neuromas. PMID:27559959

  5. Epidermoid gastric cancer review literature a case study

    International Nuclear Information System (INIS)

    Full text: introduction. epidermoid epidemiologic ally gastric cancer etiology is extremely uncommon forming a 0.04 to 0.07% of cases. target. reviewing the literature from a clinical case of a female patient 60 years epidermoid carrier loco regionally advanced gastric cancer. methodology and methods. analyze the case of gastric cancer squamous which TB diagnosed n2 m0 be a eiiic. results. the case was presented as an atypical dyspepsia was diagnosed with cancer gastric squamous after taking multiple biopsies. diagnosis is confirmed and the checked laparoscopically resectable liver infiltration, commitment vascular and pancreatic seen by ct scan. it was decided to establish treatment palliative chemotherapy based on docetaxel, 5-fluorouracil and cisplatin that fails to receive and who dies of massive haematemesis. conclusions. it is well established the pathogenesis of this disease. in series reported we found a higher incidence in males, with a median age presentation at age 64. the most common is the fun dus and diagnosis in advanced stages is most prevalent. being a rare histological subtype as there is no evidence to support a massed different therapeutic adenocarcinoma

  6. Carcinoma epidermoide del conducto auditivo externo

    Directory of Open Access Journals (Sweden)

    Javier Alfonso Rodríguez

    2009-02-01

    Full Text Available Acude a la consulta de Otorrinolaringología un paciente masculino de 43 años de procedencia urbana que comienza con una otorrea de larga evolución (aproximadamente dos años, para la que llevó numerosos tratamientos para la otitis externa que presentaba, con estos antecedentes y lo constatado al examen se decide realizar toma de muestra (biopsia de la zona, diagnosticándose un Carcinoma Epidermoide, del conducto auditivo externo, patología poco frecuente en nuestro medio.A 43 years-old, urban, male patient assists the consultation of Otolaryngology with a long evolving otorrea (around two years, receiving several treatments against the external otitis he suffered. With those antecedents and what we found when examining him, we decided to take a sample (biopsy of the area, diagnosing an epidermoid carcinoma of the left external canal, an infrequent pathology in our settings.

  7. Epidermoid carcinoma of the conjunctiva. Case report

    Directory of Open Access Journals (Sweden)

    María Adela LLull Tombo

    2011-12-01

    Full Text Available Se presenta el caso de un paciente de 76 años de edad con un carcinoma epidermoide de conjuntiva.  La manifestación clínica principal fue la molestia, el dolor y el ojo rojo. Al examen físico ocular se encontró lesión blanquecina, con vasos sanguíneos en el ángulo interno, por encima del pterigion en ojo derecho. Se diagnosticó como carcinoma epidermoide de la conjuntiva, el cual evolucionó de forma rápida e invasiva. Se intervino quirúrgicamente en tres ocasiones debido a las recurrencias.

  8. Epidermoid carcinoma of the external auditory canal

    International Nuclear Information System (INIS)

    A 43 years-old, urban, male patient assists the consultation of Otolaryngology with a long evolving otorrhea (around two years), receiving several treatments against the external otitis he suffered. With those antecedents and what we found when examining him, we decided to take a sample (biopsy) of the area, diagnosing an epidermoid carcinoma of the left external canal, an infrequent pathology in our settings

  9. Orbital dermoid and epidermoid cysts: Case study

    Directory of Open Access Journals (Sweden)

    Veselinović Dragan

    2010-01-01

    Full Text Available Introduction. Dermoid and epidermoid cysts of the orbit belong to choristomas, tumours that originate from the aberrant primordial tissue. Clinically, they manifest as cystic movable formations mostly localized in the upper temporal quadrant of the orbit. They are described as both superficial and deep formations with most frequently slow intermittent growth. Apart from aesthetic effects, during their growth, dermoid and epidermoid cysts can cause disturbances in the eye motility, and in rare cases, also an optical nerve compression syndrome. Case Outline. In this paper, we described a child with a congenital orbital dermoid cyst localized in the upper-nasal quadrant that was showing signs of a gradual enlargement and progression. The computerized tomography revealed a cyst of 1.5-2.0 cm in size. At the Maxillofacial Surgery Hospital in Niš, the dermoid cyst was extirpated in toto after orbitotomy performed by superciliary approach. Postoperative course was uneventful, without inflammation signs, and after two weeks excellent functional and aesthetic effects were achieved. Conclusion. Before the decision to treat the dermoid and epidermoid cysts operatively, a detailed diagnostic procedure was necessary to be done in order to locate the cyst precisely and determine its size and possible propagation into the surrounding periorbital structures. Apart from cosmetic indications, operative procedures are recommended in the case of cysts with constant progressions, which cause the pressure to the eye lobe, lead to motility disturbances and indirectly compress the optical nerve and branches of the cranial nerves III, IV and VI.

  10. Neuronavigation assisted decompression of trigeminal neuralgia caused by cerebellopontine angle osteoma

    Directory of Open Access Journals (Sweden)

    Iimura Yasushi

    2014-09-01

    Full Text Available Trigeminal neuralgia (TN is usually caused by vascular compression of the trigeminal nerve root entry zone, but can be caused by other factors such as tumors, vascular disorders, and demyelination in multiple sclerosis. We present a rare case with a huge osteoma located on the cerebellopontine angle (CPA and causing TN. A 48-year-old woman presented with TN caused by a huge left CPA bone tumor. Surgery was performed by the lateral suboccipital approach under neuronavigation system guidance and regional decompression of the trigeminal nerve root entry zone was achieved. Intraoperative, neuro-navigation system was very useful for identification of the trigeminal nerve entry zone because normal anatomy had been obscured by the huge osteoma. Her pain disappeared completely immediately after surgery. The histological diagnosis was osteoma. TN is an expectative symptom of CPA tumors. Osteomas should be considered in patients with CPA tumors.

  11. Solitary fibrous tumor of the cerebellopontine angle: A case report and literature review

    Directory of Open Access Journals (Sweden)

    Joe M Das

    2014-01-01

    Full Text Available Solitary fibrous tumors (SFT are rare dura-based mesenchymal tumors of the central nervous system. SFT occurring in the cerebellopontine (CP angle is very rare and only 21 cases have been reported in the literature until date. We present a 40-year-old male patient who presented with features of the right-sided facial and acoustic nerves paresis along with same sided cerebellar symptoms of 2 months duration. Magnetic resonance imaging revealed a T2 heterogeneously hyperintense extra-axial lesion, showing intense contrast enhancement in the right CP angle with solid and cystic areas. The lesion was not extending into the internal auditory canal. Digital subtraction angiography showed arterial feeders from vertebro-basilar system. The highly vascular lesion was excised near-totally by suboccipital retrosigmoid craniectomy. The lesion was diagnosed as SFT on histopathological examination and was positive for CD34 and bcl-2.

  12. Epidermoid carcinoma of the conjunctiva. Case report Carcinoma epidermoide de conjuntiva. Presentación de un caso

    Directory of Open Access Journals (Sweden)

    María Adela LLull Tombo

    2011-12-01

    Full Text Available

    The case of a 76 years old male patient with a conjunctival squamous cell carcinoma is presented. The main clinical manifestation was discomfort, pain and redness in the eye. Physical ocular examination revealed a whitish eye injury, with blood vessels in the inner corner, above the right eye pterygium. It was diagnosed as squamous cell carcinoma, which evolved rapidly and invasively. Due to recurrences, three surgeries were performed.

    Se presenta el caso de un paciente de 76 años de edad con un carcinoma epidermoide de conjuntiva.  La manifestación clínica principal fue la molestia, el dolor y el ojo rojo. Al examen físico ocular se encontró lesión blanquecina, con vasos sanguíneos en el ángulo interno, por encima del pterigion en ojo derecho. Se diagnosticó como carcinoma epidermoide de la conjuntiva, el cual evolucionó de forma rápida e invasiva. Se intervino quirúrgicamente en tres ocasiones debido a las recurrencias.

  13. Pneumocephalus in cerebellopontine angle and meningitis secondary to chronic otitis media in a child

    Directory of Open Access Journals (Sweden)

    Shailendra Ratre

    2015-01-01

    Full Text Available Pneumocephalus is a rare complication of chronic otitis media. Despite its rarity intra-cranial air carries a potential risk of increased intra-cranial pressure or meningitis, which requires immediate therapy. A 10-year-old child presented to us with complaints of fever, headache, vomiting, and decreased hearing from left ear. He had history of left ear discharge since 2 years. Clinical examination revealed neck rigidity and left chronic otitis media. Contrast enhanced computed axial tomography scan of head [Figure 1] and [Figure 2] showed pneumocephalus in left cerebellopontine angle, opacification of left middle ear and nonpneumatisation of left mastoid. Child was immediately put on empirical intravenous antibiotics and decongestants. He showed clinical improvement in 3 days. Pneumocephalus secondary to chronic otitis media is extremely rare; we are reporting one such case in a child with review of literature.

  14. An Unusual Case of Large Posterior Fossa Neurenteric Cyst Involving Bilateral Cerebellopontine Angle Cisterns: Report of a Rare Case and Review of Literature

    International Nuclear Information System (INIS)

    Intracranial neurenteric cysts are rare cystic masses of endodermal origin lined with mucin producing low columnar or cuboidal epithelium. Approximately 141 cases have been reported so far. Most of the posterior fossa neurenteric cysts are typically small, located anteriorly to the brainstem in the midline or in the cerebellopontine angle cistern area. We present a rare, histologically proven case of a large lobulated intracranial neurenteric cyst measuring 4.2 centimeters in the maximal transverse dimension and involving bilateral cerebellopontine angle cisterns. We also present a review of the literature on this uncommon finding. Imaging features of neurenteric cyst are non-specific and it should be considered in the differential diagnosis for any intracranial extraaxial cystic lesion

  15. Management of Epidermoid Carcinoma of the anus

    International Nuclear Information System (INIS)

    In two unselected, consecutive and population-based patient materials from two regions in Sweden, different treatment modalities in patients with epidermoid carcinoma of the anus have been evaluated. By using a primary radiotherapeutic approach, combined with surgery in patients with large and/or less radiosensitive tumors, considerably more surviving patients can be disease-free in the long term compared with a primarily surgical approach. In addition, several patients will have preserved anal function. Based upon these data together with the experience described in the literature, we conclude that surgery is no longer the primary treatment of choice in patients with anal carcinoma. (authors)

  16. Intraoperative Transcranial Motor-Evoked Potential Monitoring of the Facial Nerve during Cerebellopontine Angle Tumor Resection

    OpenAIRE

    Cosetti, Maura K.; Xu, Ming; Rivera, Andrew; Jethanamest, Daniel; Kuhn, Maggie A.; Beric, Aleksandar; Golfinos, John G.; Roland, J. Thomas

    2012-01-01

    Objective To determine whether transcranial motor-evoked potential (TCMEP) monitoring of the facial nerve (FN) during cerebellopontine angle (CPA) tumor resection can predict both immediate and long-term postoperative FN function.

  17. Cerebellopontine angle lipomas: magnetic resonance imaging findings in two cases

    Energy Technology Data Exchange (ETDEWEB)

    Borges, Rafael S. [Clinica de Diagnostico por Imagem Multi-Imagem, Rio de Janeiro, RJ (Brazil); Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Dept. de Radiologia; Brito, Cecilia Castelo Branco [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Fac. de Medicina; Carvalho, Gustavo A. [Clinica Bambina, Rio de Janeiro, RJ (Brazil). Dept. de Neurocirurgia; Hospital Silvestre, Rio de Janeiro, RJ (Brazil); Domingues, Romeu C. [Clinicas CDPI e Multi-Imagem, Rio de Janeiro RJ (Brazil); Gasparetto, Emerson L. [Clinicas CDPI e Multi-Imagem, Rio de Janeiro RJ (Brazil)

    2009-07-01

    Vestibular schwannomas and meningiomas are the most common lesions of the cerebellopontine angle (CPA), accounting for approximately 85-90% of the tumors seen in this location. Lipomas are rare at this topography, representing about 0.15% of the CPA lesions. These tumors are mal developmental masses that arise from abnormal differentiation of the meninx primitive. Clinically, CPA lipomas can cause slowly progressive neurological symptoms and signs affecting cranial nerves or brain stem. Because these lesions usually are strongly attached to the surrounding structures, any surgical attempts of complete resection can result in neural or vascular damage, reinforcing the importance of the pre-operative imaging diagnosis. Although the CT findings of CPA lipomas can be typical, the magnetic resonance (MR) imaging, especially the fat suppression sequences, had improved the identification of these lesions. We aimed to report two patients with a CPA lipoma, emphasizing the MR imaging findings. (author)

  18. Vascular anomalies of the cerebellopontine angle; Vaskulaere Erkrankungen des Kleinhirnbrueckenwinkels

    Energy Technology Data Exchange (ETDEWEB)

    Papanagiotou, P.; Grunwald, I.Q.; Politi, M.; Struffert, T.; Ahlhelm, F.; Reith, W. [Universitaetsklinikum des Saarlandes, Homburg/Saar (Germany). Klinik fuer Diagnostische und Interventionelle Neuroradiologie

    2006-03-15

    Vascular anomalies of the cerebellopontine angle are rare compared to tumors in this area. Irritation of the trigeminal, facial, or vestibulocochlear nerve may cause trigeminal neuralgia, hemifacial spasm and vertigo, or tinnitus accordingly. Vessel loops in the cerebellopontine cisterns may cause compression at the root entry or exit zone of the cranial nerves V, VII, and VIII, a phenomenon which is called ''vascular loop syndrome.'' Megadolichobasilar artery and aneurysms of the vertebrobasilar system can also lead to dislocation and compression of the cranial nerves and brain stem. Three-dimensional CISS MR imaging and MR angiography are useful in the detection of neurovascular compression. Microvascular decompression is an effective surgical procedure in the management of compression syndromes of the cranial nerves V, VII, and VIII. (orig.) [German] Gegenueber den Raumforderungen stellen vaskulaere Veraenderungen des Kleinhirnbrueckenwinkels eher eine Ausnahme dar. Trigeminusneuralgie, hemifazialer Spasmus und Schwindel oder Tinnitus koennen bei Irritationen des Nervus trigeminus, facialis und vestibulocochlearis auftreten. Schlingenbildungen der Gefaesse in den Kleinhirnzisternen koennen eine Kompression der Eintritts- oder Austrittszonen der Hirnnerven V, VII und VIII am Hirnstamm hervorrufen, was als ''Vascular-loop-Syndrom'' bezeichnet wird. Zu Verlagerungen und Kompressionen von Hirnnerven und Hirnstamm koennen, wenn auch seltener, die Megadolichobasilaris und Aneurysmen des vertebrobasilaeren Systems fuehren. Bezueglich der Bildgebung ist die Magnetresonanztomographie (MRT) die Methode der Wahl. Die 3D-CISS-Sequenz und die MR-Angiographie sind hilfreich zur Darstellung der neurovaskulaeren Kompression. Die Methode der mikrovaskulaeren Dekompression ist eine wirkungsvolle Methode zur Beseitigung gefaessbedingter Kompressionen der Hirnnerven V, VII und VIII. (orig.)

  19. Intracranial squamous cell carcinoma developing in remnant of an epidermoid cyst:case report and literature review

    Institute of Scientific and Technical Information of China (English)

    关丽明; 戚喜勋; 张景荣; 徐克; 崔丽娟; 张强

    2004-01-01

    @@ Epidermoid tumors, sometimes called "pearly tumor", because of the appearance of their outer surface, represent about 0.2%-1.8% of all the primary intracranial tumors1 and are benign developmental lesions. However in 1912, Ernst et al2 found a case of primary intracranial squamous cell carcinoma arising in an epidermoid cyst in autopsy and reported it. Hereafter, case reports about primary intracranial squamous cell carcinoma appeared in succession, especially after computed tomography (CT) and magnetic resonance imaging (MRI) were widely applied in clinical medicine. To our knowledge, few cases have been reported in our country until now. We present a case of intracranial squamous cell carcinoma developing in remnant of an epidermoid cyst 11 years after the operation resection with a review of the literature.

  20. Clinical Characteristics of Epidermoid Cysts of the External Auditory Canal

    Science.gov (United States)

    Kim, Go-Woon; Park, Jang-Hee; Kwon, Oh-Joon; Kim, Dong Hyun

    2016-01-01

    Background and Objectives The epidermoid cyst is a common benign disease of the skin caused by inflammation of hair cortex follicles and proliferation of epidermal cells within the dermis or superficial subcutaneous tissue. The purpose of this study was to investigate the characteristics of epidermoid cysts of the external auditory canal (EAC) by analyzing the clinical and radiologic features. Subjects and Methods The clinical records were retrospectively reviewed for patients diagnosed with epidermoid cyst of the EAC from March 2004 to December 2013. The epidermoid cysts were diagnosed clinically by endoscopy and microscopy examinations and by temporal bone CT images, and were confirmed by histopathologic examination. Characteristics of epidermoid cysts in bony EAC and cartilaginous EAC were compared. Results Eight patients had an epidermoid cyst in the bony EAC and nine patients had one in the cartilaginous EAC. Swelling and otalgia were common symptoms, but 47% of cysts were found incidentally. The mean age of patients was 49.6 years (age range, 26-67 years) in the bony EAC cases and 26.1 years (age range, 6-57 years) in the cartilaginous EAC cases. The mean size of the epidermoid cyst was 3.50 mm (size range, 2-7 mm) in the bony EAC cases and 9.55 mm (size range, 2-20 mm) in the cartilaginous EAC cases. Conclusions Comparison of epidermoid cysts of the bony EAC and the cartilaginous EAC revealed that epidermoid cysts of the bony EAC is usually found incidentally, arose in older patients and had smaller size. PMID:27144232

  1. Giant Pelvic Retroperitoneal Epidermoid Cyst: A Rare Case Report

    Directory of Open Access Journals (Sweden)

    F. Z. Fdili Alaoui

    2012-01-01

    Full Text Available Epidermoid cyst is a frequent benign cutaneous tumor. The pelvic localization does not occur very often. The literature that taps into such cases is very limited in scope. Here is a report of a 27-year-old woman with a giant pelvic retroperitoneal epidermoid cyst. The use of ultrasound exploration and computed tomography has indicated ovarian origins. The surgery also revealed a retroperitoneal epidermoid cyst, uterus and ovaries were all intact. The evacuation of a cyst was found to contain lamellas of keratin. Histology permitted us to confirm the diagnosis. The patient was faring well after two years of followup.

  2. Giant pelvic retroperitoneal epidermoid cyst: a rare case report.

    Science.gov (United States)

    Fdili Alaoui, F Z; Oussaden, A; Bouguern, H; El Fatemi, H; Melhouf, M A; Amarti, A; Ait Taleb, K

    2012-01-01

    Epidermoid cyst is a frequent benign cutaneous tumor. The pelvic localization does not occur very often. The literature that taps into such cases is very limited in scope. Here is a report of a 27-year-old woman with a giant pelvic retroperitoneal epidermoid cyst. The use of ultrasound exploration and computed tomography has indicated ovarian origins. The surgery also revealed a retroperitoneal epidermoid cyst, uterus and ovaries were all intact. The evacuation of a cyst was found to contain lamellas of keratin. Histology permitted us to confirm the diagnosis. The patient was faring well after two years of followup. PMID:23150734

  3. Epidermoid cyst of the testis: An atypical sonographic appearance.

    Science.gov (United States)

    Chen, Shu-Ting; Chiou, Hong-Jen; Pan, Chin-Chen; Shen, Shu-Huei; Chou, Yi-Hong; Tiu, Chui-Mei; Wang, Hsin-Kai; Lai, Yi-Chen; Lin, Yung-Hui; Wang, Jane; Chang, Cheng-Yen

    2016-09-01

    Epidermoid cysts are rare. They represent the most common benign tumor of the testis. The sonographic appearances of testicular epidermoid cysts usually include avascular, mostly lamellated, heterogeneous internal echotexture, with hypoechoic and hyperechoic concentric rings, accounting for the typical onion-ring appearance. On MRI, epidermoid cysts show a low-signal-intensity center, with internal concentric rings of alternating high- and low-signal intensity on T2-weighted images, which correlates with the onion-ring appearance. We report a patient with testicular epidermoid cyst with atypical ultrasound and MRI appearances that led to the erroneous initial diagnosis of "burned-out" tumor. © 2016 Wiley Periodicals, Inc. J Clin Ultrasound 44:448-451, 2016. PMID:27028726

  4. Epidermoid Cyst in the Floor of the Mouth of a 3-Year-Old

    Directory of Open Access Journals (Sweden)

    Rossana Pascual Dabán

    2015-01-01

    Full Text Available Epidermoid cysts are a rare entity in the oral cavity and are even less frequent in the floor of the mouth, representing less than 0.01% of all the cases. We present the case of a 3-year-old girl with a growth in the floor of the mouth with 2 months of evolution and without changes since it was discovered by her parents. The lesion was asymptomatic; it did not cause dysphagia, dyspnea, or any other alteration. A CT scan with contrast was done which revealed the location and exact size of the lesion, allowing an intraoral approach for its excision. The histological examination confirmed the clinical speculation of an epidermoid cyst.

  5. Epidermoid cyst in the floor of the mouth of a 3-year-old.

    Science.gov (United States)

    Pascual Dabán, Rossana; García Díez, Eloy; González Navarro, Beatriz; López-López, José

    2015-01-01

    Epidermoid cysts are a rare entity in the oral cavity and are even less frequent in the floor of the mouth, representing less than 0.01% of all the cases. We present the case of a 3-year-old girl with a growth in the floor of the mouth with 2 months of evolution and without changes since it was discovered by her parents. The lesion was asymptomatic; it did not cause dysphagia, dyspnea, or any other alteration. A CT scan with contrast was done which revealed the location and exact size of the lesion, allowing an intraoral approach for its excision. The histological examination confirmed the clinical speculation of an epidermoid cyst. PMID:25694831

  6. Epidermoid cyst of the outer ear: A case report and review of literature

    Directory of Open Access Journals (Sweden)

    Alka M Dive

    2012-01-01

    Full Text Available The purpose of this article is to present a rare case of epidermoid cyst of the outer ear in a 38-year-old male patient. During clinical examination, a soft, cystic, globular, and non-tender swelling with restricted motility and well-defined margins was seen in the retroauricular region. Skin over the swelling was normal and not attached to it. The chosen treatment was total surgical removal. The histopathological findings confirmed the diagnosis of epidermoid cyst, characterized by presence of cyst cavity lined by stratified squamous epithelium with orthokeratin production. The lumen was filled with keratin. The connective tissue capsule consisted of fibrocellular stroma with numerous endothelial lined blood capillaries, which were engorged with red blood cells. The proposed treatment was considered successful, as there was no recurrence.

  7. Atypical appearance of epidermoid cyst in tongue’s ventral surface

    Directory of Open Access Journals (Sweden)

    Claudio Maranhão Pereira

    2011-04-01

    Full Text Available Introduction: Epidermoids cysts are benign and rare lesions in oral cavity. It presents as a nodular lesion of sessile base, soft to palpation. In the oral cavity, it most happens on the floor of the mouth’s midline. Without treatment, these lesions can lead to dysphagia, dysphonia and dyspnea due to reach a large size. Objective: To report a case of a 12-year-old boy presenting a lesion on the tongue’s ventral surface causing difficult to swallow. Case report: The patient was referred to the School of Dentistry of Paulista University, complaining about an asymptomatic nodule on the tongue’s ventral surface, lasting for 10 months. Clinical examination showed the extensive fibrous mass on the tongue’s medium anterior ventral surface. Conclusion: With a clinical diagnosis of dermoid, epidermoid cyst, or lipoma, an excisional biopsy was performed. Histological examination was consistent to the diagnosis of epidermoid cyst. The patient was followed up and 2 years after surgery there was no sign of recurrence.

  8. Isolated thoracic (D5 intramedullary epidermoid cyst without spinal dysraphism: A rare case report

    Directory of Open Access Journals (Sweden)

    Sudhansu Sekhar Mishra

    2015-01-01

    Full Text Available Spinal epidermoid cyst, congenital or acquired, is mainly congenital associated with spinal dysraphism, rarely in isolation. Intramedullary epidermoid cysts (IECs are rare with less than 60 cases reported so far; isolated variety (i.e., without spinal dysraphism is still rarer. Complete microsurgical excision is the dictum of surgical treatment. A 14-year-old boy presented with 4-month history of upper backache accompanied with progressive descending paresthesia with paraparesis with early bladder and bowel involvement. His condition deteriorated rapidly making him bedridden. Neurological examination revealed upper thoracic myeloradiculopathy probably of neoplastic origin with sensory localization to D5 spinal level. Digital X-ray revealed no feature suggestive of spinal dysraphism. Contrast magnetic resonance imaging (MRI characteristics clinched the presumptive diagnosis. Near-total microsurgical excision was done leaving behind a small part of the calcified capsule densely adhered to cord. Histopathological features were confirmative of an epidermoid cyst. Postoperatively, he improved significantly with a gain of motor power sufficient to walk without support within a span of 6 months. Spinal IECs, without any specific clinical presentation, are often diagnosed based upon intraoperative and histopathological findings, however early diagnosis is possible on complete MRI valuation. Complete microsurgical excision, resulting in cessation of clinical progression and remission of symptoms, has to be limited to sub-total or near-total excision if cyst is adherent to cord or its confines.

  9. Surgical Outcomes of Cerebellopontine angle Tumors in 50 Cases

    Directory of Open Access Journals (Sweden)

    faramarz memari

    2015-01-01

    Full Text Available Introduction: To report our experience with a large series of surgical procedures for removal of cerebellopontine angle (CPA tumors using different approaches.   Materials and Methods: This was a retrospective analysis of 50 patients (mean age, 49 years with CPA tumors (predominantly acoustic neuroma who underwent surgical removal using appropriate techniques (principally a translabyrinthine approach during a 4-year period.   Results: One death occurred during this study. There were nine cases (18% of cerebrospinal fluid leak, and five patients (10% were diagnosed as having bacterial meningitis. Complete gross tumor removal was not achieved in four patients (8%. Facial nerve function as measured by the House Brackmann system was recorded in all patients 1 year following surgery: 32% had a score of 1 or 2; 26% had a score of 3 or 4; and 8% had a score of 5 or 6. Other complications included four cases of wound infection.   Conclusion:  The translabyrinthine approach was predominantly used in our series of CPA tumors, and complication rates were comparable with other large case series.

  10. An adult case of medulloblastoma in the cerebellopontine angle extending to the supratentorial area

    Institute of Scientific and Technical Information of China (English)

    Yasemin Benderli Cihan

    2010-01-01

    Medulloblastoma is an undifferentiated embryonic neuroepithelial tumor. It is a rare tumor in the central nervous system, with an even rarer occurrence during adulthood. It may develop at an atypical and uncommon site, such as the cerebellopontine angle (CPA), and such tumors rarely present with supratentorial extension. The present study reports an adult case of medulloblastoma in the CPA extending to the supratentorial area. The patient presented with complaints of headache, vertigo, hearing difficulty in the left ear, nausea/vomiting, and unsteady gait. Disequilibrium began 4 weeks earlier. Examination revealed normal cranial nerves, and computed tomography showed a hyperdense lesion, with a heterogeneously enhancing mass, in the left CPA region. The patient underwent a nearly total excision of the lesion in the CPA region.Histopathological examination confirmed medulloblastoma, WHO grade IV. Postoperatively, the patient received radiotherapy and remained asymptomatic for 30 months. However, he received two more surgeries for relapse and progression of medulloblastoma and eventually died. A CPA medulloblastoma with supratentorial extension is relatively rare in the clinic.

  11. Splenic Epidermoid Cyst during Pregnancy; Case Report and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Majid Forouzesh

    2013-10-01

    Full Text Available Cystic disease of the spleen is not frequently encountered in surgical practice. It is broadly classified as parasitic and non-parasitic, the latter being a rare entity. In this case report, an epidermoid cyst of spleen led to acute abdomen in young age pregnant woman is presented.A 26-year-old woman with 15 weeks gestational age second pregnancy referred to emergency ward with left upper quadrant pain and tenderness that ultra sonography revealed large cyst (100х110mm with internal echo in spleen in favor of hydatic cyst or abscess. The patient was managed medically for one week but developed her abdominal pain, epigastric fullness, anorexia and fever. New sonography was done for her and large cyst was detected in spleen (120х110mm. She had severe pain accompanied with anorexia and vomiting. Fetus was normal in sonography. Exploratory laprotomy with splenectomy was performed. Splenomegaly (200х130х90mm with a cyst without any adhesion and inflammation was detected. Histopathology examination showed epidermoid cyst of spleen. (140х10х90mm. Though splenic epidermoid cyst is an uncommon entity, it should be considered in the differential diagnosis of an abdominal mass in a young individual. An attempt should be made to preserve the spleen provided there is adequate parenchyma otherwise splenectomy is the rule.

  12. Nonvestibular schwannoma tumors in the cerebellopontine angle: A structured approach and management guidelines

    DEFF Research Database (Denmark)

    Springborg, J.B.; Poulsgaard, L.; Thomsen, Jens Christian

    2008-01-01

    The most common cerebellopontine angle (CPA) tumor is a vestibular schwannoma, but one in five CPA tumors are not vestibular schwannomas. These tumors may require different management strategies. Compared with vestibular schwannomas, symptoms and signs from cranial nerve VIII are less frequent...

  13. Diffusion-weighted MR imaging (DWI) in two intradural spinal epidermoid cysts

    Energy Technology Data Exchange (ETDEWEB)

    Thurnher, Majda M. [Medical University of Vienna, Vienna (Austria)

    2012-11-15

    Epidermoid cysts are rare, benign, congenital, slow-growing inclusion cysts. On T1 and T2 weighted NMR images epidermoid cysts show heterogeneity and lack of contrast enhancement. Based on signal intensities on conventional sequences, epidermoid cysts cannot be distinguished from other neoplastic lesions. When located in the spinal cord, differential diagnosis includes ependymoma, astrocytoma, cavernoma and metastasis. Diffusion-weighted imaging (DWI) has been shown to accurately distinguish intracranial epidermoid tumors from arachnoid cysts. DWI findings in two patients with surgically proven epidermoid cysts in the spinal canal are reported.

  14. Epidermoid cyst at a rare location, as a content of inguinal hernia: A case report with a review of the literature

    Science.gov (United States)

    Meher, Sadananda; Baijal, Manish; Soni, Vandana; Sharma, Anil; Khullar, Rajesh; Chowbey, Pradeep

    2016-01-01

    Epidermoid cysts can occur in a variety of locations including the face, trunk, neck, extremities, and scalp. No case of epidermoid cyst as content of inguinal hernia has been reported so far; however, cases with dermoid, teratoma, lipoma, lymphangioma and leiomyoma as content of inguinal canal have been reported. A 29-year-old female presented with a lump in the left inguinal region that was clinically diagnosed as left inguinal hernia. The patient was planned for laparoscopic inguinal hernia repair after routine investigation. Intraoperatively, a cystic mass was found to be attached to the left round ligament that was excised completely. Histopathological report was consistent with epidermal inclusion cyst. Inguinal epidermoid cyst mimicking inguinal hernia is a rare entity. If such a cyst is encountered during operation, it should be completely excised. PMID:27279405

  15. Epidermoid carcinomas of the conjunctive with intraorbital and intraocular invasion

    International Nuclear Information System (INIS)

    The epidermoid carcinomas of the conjunctive are tumors in general of low incidence with a range between 0.13 and 1.9 cases for 100,000 inhabitants; this incidence is superior however in tropical countries. The incidences reported for intra orbital and intraocular invasive forms have a range between 2 and 12% which demonstrates the aggressive character of this tumor. The handling of epidermoid carcinoma of the conjunctive in initial stages is very conservative, but in their natural history this tumor can invade the ocular globe, orbit, neighboring regions and distant organs, thereby of importance an early diagnosis and an appropriate treatment. Our objective was to know the incidence of epidermoid carcinoma of the conjunctiva with intraocular and intra orbital invasion in the Havana National Oncology Institute. We carry out a retrospective and descriptive study of 18 patients with clinical diagnoses and histology of epidermoid carcinoma of the conjunctiva with orbit infiltration assisted from January of 1995 until December 2003 classified as T4 NO MO. The evaluated parameters were: age, sex, initial treatment and evolution. Middle aged of our serie it was 58.7 years, excisional surgery and deep radiotherapy was the initial treatment applied in 83.33% of the cases. In its evolution eight cases (44.44%) of the patients had unfavorable result and radical surgery was carried out in 50% of the patients. (The author)

  16. Subtotal resection and omentoplasty of the epidermoid splenic cyst: a case report

    Science.gov (United States)

    Spahija, Gazmend S; Hashani, Shemsedin I; Osmani, Eshref A; Hoxha, Sejdullah A; Hamza, Astrit H; Gashi-Luci, Lumturije H

    2009-01-01

    Introduction Nonparasitic splenic cysts are uncommon clinical entity and because of it, there is no information regarding their optimal surgical treatment. Case presentation A 41-years-old female with incidentally diagnosed nonparasitic splenic cyst which initially was asymptomatic. After two years of follow up, the patient underwent surgery; subtotal cystectomy and omentoplasty as an additional procedure. Postoperative course was uneventful. Conclusion Short and mid term results showed that near total cystectomy with omentoplasty was a safe successful procedure for treatment of epidermoid splenic cyst. PMID:19829799

  17. Prognostic factors in megavoltage radiation therapy of central epidermoid lung carcinoma

    International Nuclear Information System (INIS)

    Radical program radiotherapy was provided to 403 patients with inoperable central epidermoid lung carcinoma that does not extend beyond one half of the thoracic cavity. Long-term therapeutic results depend on numerous factors the interrelationships of which cannot be revealed without present-day methods of data analysis. The use of computers (a method of parameter grouping and semi-automatic classification - ''teaching without a teacher'') made it possible before treatment to approach the level of group prognosis by symptoms; taking into account the time course of symptoms in the process of radiation therapy and after its termination - to reach the level of individual prognosis for 22% of the patients

  18. Computed tomography and magnetic resonance imaging of acquired abnormalities of the inner ear and cerebello-pontine angle; CT und MRT erworbener Veraenderungen des Innenohrs und Kleinhirnbrueckenwinkels

    Energy Technology Data Exchange (ETDEWEB)

    Grampp, S.; Czerny, C.; Henk, C.B.; Imhof, H. [Abteilung fuer Osteologie, Univ.-Klinik fuer Radiodiagnostik, Wien (Austria); Gstoettner, W. [Univ.-Klinik fuer Hals-Nasen-Ohren-Heilkunde, Frankfurt/Main (Germany)

    2003-03-01

    CT and MRI of acquired abnormalities of the inner ear and cerebello-pontine angle present themselves with very typical findings. The imaging should be adapted to the pathology looked for and either CT or MRI should be used alone or in combination.CT, especially high resolution CT (HRCT), provides an excellent bone contrast, while MRI has a much superior soft tissue contrast. Acute inflammatory changes of the inner ear are solely depicted by contrast-enhanced MRI. HRCT excellently depicts osseous changes of the inner ear and cerebellopontine angle such as chronic ossifying labyrinthitis occurring after acute labyrinthitis, otosclerotic or traumatic changes. Tumorous changes not yielding to bony changes are best delineated by MRI. Posttraumatic hemorrhage and chronic fibrotic changes within the labyrinth are depicted by MRI, only. In conclusion HRCT and MRI are excellent methods to delineate acquired abnormalities of the inner ear and cerebello-pontine angle. HRCT best depicts osseous changes while MRI best depicts soft tissue changes. HRCT and MRI are not concurrent methods but should better be used as complementary methods for imaging acquired abnormalities of inner ear and cerebellopontine angle. (orig.) [German] Bei erworbenen Veraenderungen des Innenohrs und der Kleinhirnbrueckenwinkelregion zeigen CT und MRT typische Bildcharakteristika, wobei die Bildgebung der zu suchenden Veraenderung angepasst werden sollte. Die CT liefert hochaufloesend (HRCT) einen exzellenten Knochen-, die MRT einen hervorragenden Weichteilkontrast. Akute entzuendliche Veraenderungen sind in der HRCT nicht erkennbar, sondern nur in der kontrastmittelverstaerkten MRT. Die HRCT erfasst am besten knoecherne Veraenderungen wie Ossifikationen des membranoesen Labyrinths im Rahmen einer chronischen Entzuendung, otosklerotische und traumatische Veraenderungen - selbst wenn diese nur diskret sind. Tumoroese Veraenderungen, die zu keiner ossaeren Veraenderung fuehren wie kleine Schwannome sowie

  19. Intraoral removal of a large epidermoid cyst of the floor of the mouth. A case report and review of the literature.

    Directory of Open Access Journals (Sweden)

    Fotios TZERMPOS

    2014-12-01

    Full Text Available SUMMARY: The intraoral dermoid cysts constitute less than 0.01% of all oral cavity cysts and are most commonly located in the midline of the floor of the mouth. Histologically they are divided into epidermoid, dermoid and teratoid. The surgical excision can be performed either intraorally or extraorally and the choice of treatment can be determined by the localization and the size of the lesion. In this article, a case of a large epidermoid cyst of the floor of the mouth removed by intraoral excision under local anesthesia with i.v. sedation is presented.

  20. Leech therapy for epidermoid cysts and review of the literature

    Directory of Open Access Journals (Sweden)

    Abbas Rasi

    2014-01-01

    Full Text Available Hirudo medicinalis sucks blood directly through the external mammalian skin. We recently observed a healthy 64-year-old Iranian man, who presented with numerous asymptomatic multilobular oval-to-round well-defined 0.5 to 1.5 cm cystic lesions with central umbilication (central black eschar over the upper portion of his chest. We made the diagnosis of epidermoid cyst, giant comedone and leech bite on the basis of the constellation of clinical features. The patient was treated with oral ciprofloxacin at a dose of 2 g daily, and 2% topical erythromycin solution. Despite improvement, the evidence of cystic lesions persisted. There was no history of similar lesions in any other family member. There was no history of trauma. The patient was not using any topical or systemic medication. Two weeks before his visit, he had a history of leech therapy under the supervision of a general practitioner. His medical history was significant for leech therapy of the lesions, five days previously. He was followed up for another two weeks and after disappearance of the inflammation, with the patient under local anesthesia, the well-circumscribed mass was completely evacuated with a sharp curette and comedone extractor. The patient was subsequently lost to follow-up. Conclusion: Considering the efficacy of leeches, it would be favorable to breed a germ-free leech. In Iran, the use of the leeches in surgery, in recent years, has been infrequent. It appears that the positive effects of this ancient remedy may now be explained through scientific methods, promising potentially even more uses of this admirable creature in medicine.

  1. Imaging diagnosis of various small lesions in the cerebellopontine angle by Suboccipital air CT cisternography

    Energy Technology Data Exchange (ETDEWEB)

    Tsukahara, Kaoru (Toho Univ., Tokyo (Japan). School of Medicine)

    1989-11-01

    A modified air CT cisternography technique, characterized by suboccipital air infusion was carried out in a total of 180 patients over the past 5 years. The patients were divided into two groups according to their suspected lesions. The first group consisted of 151 patients who were diagnosed as having retrolabyrinthine lesions by neurootological examinations; 29 patients with facial twitching or trigeminal neuralgia were classified in the second group. In the first group, air CT cisternography revealed 21 cases of small acoustic tumors including intracanalicular tumors. Additionally, several unexpected small lesions were detected in the cerebellopontine angle. These included small meningiomas, osteoma, osteogenic tumor, nodulated acoustic nerve in neurofibromatosis, primary acoustic nerve atrophy, adhesive arachnoiditis, elongated basilar artery and patulous acoustic meatus. In the second group, the causative artery of neurovascular compression at the nerve exit zone failed to be confirmed in many cases, but satisfactory preoperative information concerning nerves and vessels in the cerebellopontine angle were provided by air CT cisternography. The advantages and disadvantages of air CT cisternography and MRI-CT for the diagnosis of small lesions in the cerebellopontine angle are also discussed. (author).

  2. Intratesticular and intraovarian epidermoid inclusion cysts: report of two cases

    Directory of Open Access Journals (Sweden)

    Guilherme José Morgan

    2013-04-01

    Full Text Available Two rare cases of intragonadal epidermoid inclusion cysts are described. Their etiology remains controversial and a possible hypothesis is monodermal abortive teratomas, with no mesodermal and endodermal components. As the ultrasound test results were inconclusive, it became difficult to rule out the possibility of neoplasm. Therefore, patients were submitted to radical therapy. The definitive diagnosis for both cases was provided by the anatomopathological examination.

  3. Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells.

    Science.gov (United States)

    Li, Hui; Zhou, Fusheng; Du, Wenhui; Dou, Jinfa; Xu, Yu; Gao, Wanwan; Chen, Gang; Zuo, Xianbo; Sun, Liangdan; Zhang, Xuejun; Yang, Sen

    2016-05-01

    Melanoma, the most aggressive form of skin cancer, causes more than 40,000 deaths each year worldwide. And epidermoid carcinoma is another major form of skin cancer, which could be studied together with melanoma in several aspects. Asparagine synthetase (ASNS) gene encodes an enzyme that catalyzes the glutamine- and ATP-dependent conversion of aspartic acid to asparagine, and its expression is associated with the chemotherapy resistance and prognosis in several human cancers. The present study aims to explore the potential role of ASNS in melanoma cells A375 and human epidermoid carcinoma cell line A431. We applied a lentivirus-mediated RNA interference (RNAi) system to study its function in cell growth of both cells. The results revealed that inhibition of ASNS expression by RNAi significantly suppressed the growth of melanoma cells and epidermoid carcinoma cells, and induced a G0/G1 cell cycle arrest in melanoma cells. Knockdown of ASNS in A375 cells remarkably downregulated the expression levels of CDK4, CDK6, and Cyclin D1, and upregulated the expression of p21. Therefore, our study provides evidence that ASNS may represent a potential therapeutic target for the treatment of melanoma. PMID:25858017

  4. FGF2 mediates DNA repair in epidermoid carcinoma cells exposed to ionizing radiation

    International Nuclear Information System (INIS)

    Fibroblast growth factor 2 (FGF2) is a well-known survival factor. However, its role in DNA repair is poorly documented. The present study was designed to investigate in epidermoid carcinoma cells the potential role of FGF2 in DNA repair. The side population (SP) with cancer stem cell-like properties and the main population (MP) were isolated from human A431 squamous carcinoma cells. Radiation-induced DNA damage and repair were assessed using the alkaline comet assay. FGF2 expression was quantified by enzyme linked immunosorbent assay (ELISA). SP cells exhibited rapid repair of radiation induced DNA damage and a high constitutive level of nuclear FGF2. Blocking FGF2 signaling abrogated the rapid DNA repair. In contrast, in MP cells, a slower repair of damage was associated with low basal expression of FGF2. Moreover, the addition of exogenous FGF2 accelerated DNA repair in MP cells. When irradiated, SP cells secreted FGF2, whereas MP cells did not. FGF2 was found to mediate DNA repair in epidermoid carcinoma cells. We postulate that carcinoma stem cells would be intrinsically primed to rapidly repair DNA damage by a high constitutive level of nuclear FGF2. In contrast, the main population with a low FGF2 content exhibits a lower repair rate which can be increased by exogenous FGF2. (authors)

  5. Metastatic Extrapulmonary Small Cell Carcinoma to the Cerebellopontine Angle: A Case Report and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Debebe Theodros

    2015-01-01

    Full Text Available Extrapulmonary small cell carcinomas (EPSCC are rare malignancies with poor patient prognoses. We present the case of a 63-year-old male who underwent surgical resection of a poorly differentiated small cell carcinoma, likely from a small intestinal primary tumor that metastasized to the cerebellopontine angle (CPA. A 63-year-old male presented with mild left facial paralysis, hearing loss, and balance instability. MRI revealed a 15 mm mass in the left CPA involving the internal auditory canal consistent with a vestibular schwannoma. Preoperative MRI eight weeks later demonstrated marked enlargement to 35 mm. The patient underwent a suboccipital craniectomy and the mass was grossly different visually and in consistency from a standard vestibular schwannoma. The final pathology revealed a poorly differentiated small cell carcinoma. Postoperative PET scan identified avid uptake in the small intestine suggestive of either a small intestinal primary tumor or additional metastatic disease. The patient underwent whole brain radiation therapy and chemotherapy and at last follow-up demonstrated improvement in his symptoms. Surgical resection and radiotherapy are potential treatment options to improve survival in patients diagnosed with NET brain metastases. We present the first documented case of skull base metastasis of a poorly differentiated small cell carcinoma involving the CPA.

  6. A comparative anatomical CT study of the vascular and nervous structures of the cerebello-pontine angle

    International Nuclear Information System (INIS)

    The arteries and veins of the cerebellopontine angle have been injected with a contrast medium permitting a precise anatomical reconnaissance of their topography and relations. These specimens have been explored by CT in order to define the opacified vessels and to differentiate them from the adjacent nervous tissue. Thus in CT it is possible to locate the cerebellar arteries, the petrous and medullo-pontine veins and the nerves of the cerebello-pontine angle. This study describes the normal appearance of the flocculus on CT and the criteria to distinguish the flocculus from the arteries and veins. Moreover it should contribute to the definition of the criteria of reliability of a CT diagnosis and its limits in the cerebello-pontine angle. (orig.)

  7. Prognostic role of p53 protein expression in epidermoid carcinoma of the anal canal

    International Nuclear Information System (INIS)

    (p 0.01). Conclusions: It is concluded that expression for p53 protein is present in a high percentage of patients with epidermoid carcinoma of the anal canal. For patients managed with combined XRT, 5-FU, and MMC, percent p53 protein expression is of prognostic value for DFS independent of other clinical factors such as T category, gender, and histology

  8. [Laryngeal epidermoid carcinoma in a young adult without risk factors: a case report].

    Science.gov (United States)

    M'barek, Basma; Gargouri, W; Maalej, M

    2005-08-01

    Head and neck carcinomas are rare in young patients without a history of tobacco consution, tho two classical risk factors. Our report is about 20 year-old patient without a history exosure to radiations or of alcohol / tobacco consumption, who presented with repeated episodes of dysphonia that didn't improve under medical treatment. Endoscopy showed a fungating hemilaryngeal lesion with a histology of epidermoid carcinoma stage T3N0. The patient initially 3 courses of cisplatin-5 fluorouracil resulting in a 90% objective response, followed by a loco-regional radiotherapy. 36 months after the diagnosis and 24 after the end of therapy, the patient is still alive and in complete remission. PMID:16238282

  9. Isodense epidermoid cyst in the pineal region. Case report

    Energy Technology Data Exchange (ETDEWEB)

    Yamanouchi, Yasuo; Takahara, Nobuhiko; Kawamura, Yasuo; Matsumura, Hiroshi

    1985-02-01

    A 69-year-old male was admitted complaining of gait disturbances and diplopia, 2.5 years after an episode of serous meningitis. Neurological examination on admission disclosed Parinaud's sign, unsteady gait and dysdiadochokinesis on the left side. A striking finding on the computerized tomography (CT) was the left to right shift of the posterior portion of the third ventricle without visualization of the quadrigeminal and ambient cisterns, which were almost completely occupied by an isodense mass accompanied by high dense flecks and a low dense part. Enhanced CT showed positive enhancement in the vicinity of the pineal calcification. By the suboccipital supracerebellar approach, an encapsulated mass containing brownish yellow fluid was subtotally removed and a histological examination of it revealed epidermoid tissue and hemosiderin deposits in the solid portion. Few reports of isodense epidermoid cysts have so far been found in the literature giving a full explanation for this unusual CT attenuation value. Based on the clinical course and histology of this case, the pathogenesis of the unusual density is discussed along the following lines: The mixture of the low dense factor due to cholesterin and the high dense factor due to prior bleeding is believed to result in the isodense attenuation value in the liquid portion. Also, in the solid part, a microscopically mixed texture of deposited hemosiderin and cholesterin clefts in the inflammatory granulomatous tissue could explain its density on the CT scan.

  10. A case of a spontaneously ruptured epidermoid cyst

    International Nuclear Information System (INIS)

    Intracranial fat-containing congenital tumors are characterized by negative absorption values on CT. We hereby report a case of an epidermoid cyst with subarachnoid free fats diagnosed preoperatively by CT. A 21-year-old female was admitted to our hospital because of continuous mild headache and nausea. At the time of admission, the results of her physical and neurological examinations were normal. CT, however, demonstrated multiple subarachnoid low-density spots and a suprasellar low-density area with high-density spots. In addition, there were negative absorption values (-12 ∼ -77), suggesting free fats. A spontaneously ruptured epidermoid or dermoid cyst was diagnosed on the basis of these findings. At surgery, a suprasellar tumor containing a yellowish, cheese-like material was confirmed. The patient made an uneventful recovery and was discharged 14 days after surgery. There have been several published reports of CT appearances of intracranial fat-containing tumors. However, spontaneously ruptured cases diagnosed by CT are rare. CT was found to be useful for the diagnosis of spontaneously ruptured cases of fat-containing tumors. (author)

  11. Re-irradiation in stereotactic conditions and cetuximab for local relapses of epidermoid carcinoma of head and neck; Reirradiation en conditions stereotaxiques et cetuximab pour des recidives locales de carcinome epidermoide de la tete et du cou

    Energy Technology Data Exchange (ETDEWEB)

    Vasseur, F.; Comet, B.; Faivre-Pierret, M.; Coche-Dequeant, B.; Degardin, M.; Lefebvre, J.L.; Lacornerie, T.; Lartigau, E. [Departement universitaire de radiotherapie, centre Oscar Lambret, 59 - Lille (France); Universite Lille-2, 59 (France)

    2010-10-15

    The authors report a work aimed at assessing the feasibility and toxicity of a re-irradiation treatment in stereotactic conditions using CyberKnife and cetuximab in the case of local relapses of epidermoid cancers of the ORL sphere. Thirty three patients have been submitted to this treatment between June 2007 and April 2009. Although six patients died by six months, this treatment seems to be a good alternative, and presents an acceptable short-term toxicity. Further studies are needed to compare this technique to other therapeutic techniques, and to assess the risk of long term complications. Short communication

  12. Review of photodynamic therapy with 5-methyl aminolevulinate in actinic keratosis, epidermoid carcinoma and basal cell carcinoma

    International Nuclear Information System (INIS)

    A bibliographic review was conduced on the use of 5-methyl aminolevulinate in dermatology, specifically in the treatment of actinic keratosis, epidermoid carcinoma and basal cell carcinoma. The basic fundamentals of photodynamic therapy are described. The preparation and method of use of photodynamic therapy with 5-methyl aminolevulinate (MAL-PDT) are detailed. The clinical studies that were realized with photodynamic therapy for the treatment of actinic keratosis, epidermoid carcinoma and basal cell carcinoma are mentioned. Different photo-inducible agents and other current therapeutic options of first-line are compared. The MAL-PDT has have the advantage of to present less side effects and the same have been more tolerable than liquid nitrogen and 5 fluorouracil. The MAL-PDT has been considered as an effective option for the treatment of Bowen's disease. Invasive epidermoid carcinoma has existed without evidence to support the routine use of this therapeutic. For superficial basal cell carcinoma, the MAL-PDT has presented a high cure rate and transient and manageable side effects in extensive and multiple lesions. The MAL-PDT has been an effective and safe treatment in patients with basal cell carcinoma, for those with less depth of 2mm. The MAL-PDT could play an important role in the field of prevention with immunosuppressed patients, particularly, those that have required transplant and its immunosuppression has been pharmacological. The use or not of the MAL-PDT, should be evaluated individually for each patient and to have suitable characteristics for each disease that was cited in this review. The photodynamic therapy with 5-methyl aminolevulinate has been a therapeutic modality of considerable economy, however, it should be evaluated in the context of number of inquiries and side effects that have offered other therapeutic modalities

  13. Does the location of a vascular loop in the cerebellopontine angle explain pulsatile and non-pulsatile tinnitus?

    Energy Technology Data Exchange (ETDEWEB)

    Nowe, V.; Wang, X.L.; Gielen, J.; Goethem, J.Van; Oezsarlak, Oe.; De Schepper, A.M.; Parizel, P.M. [University of Antwerp, Department of Radiology, Edegem (Belgium); Ridder, D. De [University of Antwerp, Department of Neurosurgery, Edegem (Belgium); Heyning, P.H.Van de [University of Antwerp, Department of Otorhinolaryngology, Edegem (Belgium)

    2004-12-01

    The purpose was to investigate patients with unexplained pulsatile and non-pulsatile tinnitus by means of MR imaging of the cerebellopontine angle (CPA) and to correlate the clinical subtype of tinnitus with the location of a blood vessel (in the internal auditory canal or at the cisternal part of the VIIIth cranial nerve). Clinical presentation of tinnitus and perceptive hearing loss were correlated. In 47 patients with unexplained tinnitus, an MR examination of the CPA was performed. Virtual endoscopy reconstructions were obtained using a 3D axial thin-section high-resolution heavily T2-weighted gradient echo constructive interference in steady state (CISS) data-set. High-resolution T2-weighted CISS images showed a significantly higher number of vascular loops in the internal auditory canal in patients with arterial pulsatile tinnitus compared to patients with non-pulsatile tinnitus (P<0.00001). Virtual endoscopy images were used to investigate vascular contacts at the cisternal part of the VIIIth cranial nerve in patients with low pitch and high pitch non-pulsatile tinnitus. A significantly different distribution of the vascular contacts (P=0.0320) was found. Furthermore, a correlation between the clinical presentation of non-pulsatile tinnitus (high pitch and low pitch) and the perceptive hearing loss was found (P=0.0235). High-resolution heavily T2-weighted CISS images and virtual endoscopy of the CPA can be used to evaluate whether a vascular contact is present in the internal auditory canal or at the cisternal part of the VIIIth cranial nerve and whether the location of the vascular contact correlates with the clinical subtype of tinnitus. Our findings suggest that there is a tonotopical structure of the cisternal part of the VIIIth cranial nerve. A correlation between the clinical presentation of tinnitus and hearing loss was found. (orig.)

  14. Lipoma do ângulo pontocerebelar: relato de caso Lipoma of the cerebellopontine angle: case report

    Directory of Open Access Journals (Sweden)

    WALTER JOSÉ FAGUNDES-PEREYRA

    2000-09-01

    Full Text Available Os lipomas do ângulo pontocerebelar são tumores muito raros. Em geral são assintomáticos, achados fortuitos em autópsia, tomografia computadorizada (TC de crânio ou ressonância nuclear magnética do encéfalo. Os autores apresentam o caso de paciente, feminina, branca, 14 anos, há três anos com diminuição da audição à esquerda e há um ano com cefaléia, tipo hemicrânia à esquerda. A TC de crânio evidenciou lesão hipodensa, sem captação de contraste, no ângulo pontocerebelar esquerdo. A paciente foi submetida a cirurgia por via retrossigmóidea para abordagem da lesão, que se apresentou de coloração amarelada, característica de tecido adiposo. Tendo em vista o envolvimento de estruturas nervosas (VII e VIII nervos cranianos, optou-se pela exérese parcial da lesão. A paciente evoluiu com melhora da cefaléia, sem piora do déficit auditivo. Após três anos de seguimento, mantém o quadro estável. Conclui-se que os lipomas do ângulo pontocerebelar, quando assintomáticos, podem ser tratados conservadoramente. Entretanto aqueles associados a sintomatologia persistente e progressiva devem ser operados. A exérese total ou parcial vai depender do envolvimento ou não das estruturas neurovasculares adjacentes.Lipoma of the cerebellopontine angle is a very rare tumor. We report the case of a 14-years-old female, with left side deafness during three years, associated with headache. CT scan showed an hypodense mass, without enhancement at the cerebellopontine angle. The patient was treated surgically by left retrosigmoid approach. The lesion involved the eighth and seventh cranial nerves and only a partial removal was performed. The postoperative course was uneventful. She had no more headache; the deafness of the left side remained unchanged. Asymptomatic lipoma of the cerebellopontine angle can be treated conservatively, although those with progressive symptoms should be treated surgically, with total or partial remove

  15. Intranasal epidermoid cyst causing upper airway obstruction in three brachycephalic dogs.

    Science.gov (United States)

    Murgia, D; Pivetta, M; Bowlt, K; Volmer, C; Holloway, A; Dennis, R

    2014-08-01

    This case report describes three brachycephalic dogs with intranasal epidermoid cysts that were causing additional upper airway obstruction. Although epidermoid cysts have been described in several locations in dogs, to the authors' knowledge intranasal epidermoid cysts have not been previously reported. All dogs had mucopurulent to haemorrhagic nasal discharge. Magnetic resonance imaging of the head revealed the presence of unilateral or bilateral intranasal cystic lesions obstructing the nasal cavities partially or completely, with atrophy of the ipsilateral nasal turbinates. The cystic lesions were surgically excised in all dogs using a modified lateral alveolar mucosal approach to the affected nasal cavity. Aerobic, anaerobic and fungal culture of the cystic contents were negative and histology of the excised tissue was consistent with a benign intranasal epidermoid cyst in each dog. Upper airway obstruction was clinically improved in two dogs. PMID:24697627

  16. Epidermoid cyst radiologically mistaken as a left sided subpulmonic effusion.

    Science.gov (United States)

    Sameh, Ibrahim Sersar; Gewaeli, NourEldeen Noaman; Hamza, Usama Ali; Awadalla, Mohammed Mounir el-said

    2003-09-01

    A 33-year-old female had a left sided chest pain for the last 3 months. Chest X-ray showed a left basal opacity. Computed tomography chest suggested a left sided subpulmonic effusion (17.5x12.2x13 cm) with thick enhanced walls with marked collapse of the left lower lobe and displacement of the heart and mediastinum to the right side. Trial of thoracocentesis was done and it was positive. Trial of intercostal tube insertion was done with a sense of very thick pleura and the patient developed a vasovagal attack. Accordingly, exploratory thoracotomy was decided. Intraoperative assessment showed a huge anterosuperior mediastinal cyst attached to the pericardium and was successfully resected. The pathological findings were compatible with epidermoid cyst. PMID:17670071

  17. Perspectives for the treatment of epidermoid oesophageal cancer

    International Nuclear Information System (INIS)

    Prior to the eighties, most patients with a diagnosis of epidermoid oesophageal cancer only received palliative symptomatic care. To date, most all undergo either surgery or medical treatment or both. Late diagnosis due to lack of clinical signs in the early phases of the disease, and perhaps insufficient attempts at identifying patients at risk who could benefit from systematic screening, is still an important problem although the number of diagnosed cases continues to rise (from 104 in 1985 to 151 in 1989 in Finistere in western France). Two different therapeutic attitudes could improve the prognosis: extensive surgery as proposed by the Japanese with dissection of all invaded lymph nodes whatever the localization and a multimodal approach combining radiochemotherapy and surgery. Although outcome can apparently be improved in certain types of oesophageal cancer, the proposal of aggressive extensive dissection could have an effect on respiratory complications and would not necessarily be adapted to the risk involved in western patients. Certain teams have nevertheless taken this route and will soon report their results. In France two phase II trials combining radiotherapy, chemotherapy (cisplatinium) and surgery have reported encouraging results with complete sterilization in 24% of the cases and 50% survival at 18 months. In our own series of 68 patients, we have obtained 41% sterilization and 56,3% survival at 3 years with the multi-modal protocol. The high number on non-responders to chemotherapy emphasizes the importance of maintaining surgical resection whenever possible. The discouraging reports published before 1980 have been contradicted by improvements in outcome achieved over the last decade. Today, all patients with a diagnosis of epidermoid cancer of the oesophagus should benefit from either palliative or curative care based on the latest advances in radiotherapy, chemotherapy and surgery. (author). 10 refs

  18. Retrorectal epidermoid cyst with unusually elevated serum SCC level, initially diagnosed as an ovarian tumor

    OpenAIRE

    Noriyuki Inaba; Kazumi Tada; Ichio Fukasawa; Nobuaki Kosaka; Akiko Shoda; Keiichi Kubota; Hitoshi Nagata; Takahiro Fujimori; Shigeki Tomita; Masaru Hayashi

    2009-01-01

    Retrorectal epidermoid cyst is one of the developmental cysts which arise from remnants of embryonic tissues. We report a rare case of retrorectal epidermoid cyst, initially diagnosed as an ovarian tumor. Serum SCC value as tumor marker was elevated to the high level. Laparoscopy revealed ovaries, uterus and other pelvic organs were all normal. This tumor existed in the retroperitoneal cavity and compressed the rectum. Later, complete tumor resection was performed by laparotomy. Histological ...

  19. Platelet-derived growth factor type BB and collagen matrix for soft tissue reconstruction after muco-epidermoid carcinoma removal: A possible therapeutic option

    Directory of Open Access Journals (Sweden)

    Marco Cicciù

    2015-01-01

    Full Text Available Muco-epidermoid carcinoma (MEC is a rare malignant tumor occurring in major and minor salivary glands. The described case shows a patient undergoing tumor resection without neck dissection. A quick diagnosis performed through clinical investigation and incisional biopsy revealed the nature of the tumor. A porcine collagen matrix was applied after the surgery in order to improve soft tissue healing. The matrix was saturated with platelet-derived growth factor type BB in order to favorite healing process and then fixed on the palate with a dental support device. Follow-up visit performed at first, second, and third weeks highlighted a quick healing of oral mucosa. Here reported is a case of a 34-year-old man who developed a muco-epidermoid oral carcinoma localized in the left upper jaw palatal side. The clinical, radiographic, and histopathologic findings, plus differential diagnoses of the case and reconstructive treatment options are also presented.

  20. Diagnosis and treatment of ependymoma of the cerebellopontine angle: a report of four cases

    International Nuclear Information System (INIS)

    Objective: To investigate the clinical feature and management of ependymoma of the cerebellopontine angle (CPA). Methods: Between 2002 and 2012, 4 patients with ependymoma of the CPA were treated in the General Hospital of Nanjing Military Command. The clinical data, image manifestations, operation and histopathological features were retrospectively analyzed with reference to domestic and foreign literature. Results: The clinical manifestations of 4 patients were similar to those of other CPA tumors, but imaging and pathology showed otherwise. The ependymoma was totally resected under a surgical microscope in 3 cases, and was subtotally resected in the other one. All were followed up 12-60 months and benefited from good therapeutic effect. Conclusion: Ependymoma of the CPA is rare, correct diagnosis and treatment of which requires rich clinical experience. (authors)

  1. Posterior internal auditory canal closure following the retrosigmoid approach to the cerebellopontine angle.

    Science.gov (United States)

    Leonetti, J P; Anderson, D E; Newell, D J; Smith, P G

    1993-01-01

    The retrosigmoid approach is utilized in a variety of cerebellopontine angle and internal auditory canal procedures. Drill curettage of the posterior internal auditory canal enhances lateral exposure, however, this step may also increase the patient's risk for postoperative cerebrospinal fluid (CSF) otorrhea. Obliteration of perilabyrinthine air cells is technically difficult and muscle graft displacement frequently occurs. A technique for posterior petrous dural flap stabilization of a temporalis muscle plug has proved successful in decreasing the risk of postoperative CSF fistula following retrosigmoid surgery. Temporal bone air-cell anatomy, as it relates to retrosigmoid, posterior internal auditory canal surgery is reviewed. Our technique for internal auditory canal closure, with bone wax, bone paté, muscle grafts, and petrous ridge dural flaps is outlined. PMID:8424473

  2. Diffusion tensor mode in imaging of intracranial epidermoid cysts: one step ahead of fractional anisotropy

    International Nuclear Information System (INIS)

    The signal characteristics of an epidermoid on T2-weighted imaging have been attributed to the presence of increased water content within the tumor. In this study, we explore the utility of diffusion tensor imaging (DTI) and diffusion tensor metrics (DTM) in knowing the microstructural anatomy of epidermoid cysts. DTI was performed in ten patients with epidermoid cysts. Directionally averaged mean diffusivity (Dav), exponential diffusion, and DTM-like fractional anisotropy (FA), diffusion tensor mode (mode), linear (CL), planar (CP), and spherical (CS) anisotropy were measured from the tumor as well as from the normal-looking white matter. Epidermoid cysts showed high FA. However, Dav and exponential diffusion values did not show any restriction of diffusion. Diffusion tensor mode values were near -1, and CP values were high within the tumor. This suggested preferential diffusion of water molecules along a two-dimensional geometry (plane) in epidermoid cysts, which could be attributed to the parallel-layered arrangement of keratin filaments and flakes within these tumors. Thus, advanced imaging modalities like DTI with DTM can provide information regarding the microstructural anatomy of the epidermoid cysts. (orig.)

  3. Evaluation of MR cisternography of the cerebellopontine angle using a balanced fast-field-echo sequence: preliminary findings

    Energy Technology Data Exchange (ETDEWEB)

    Tsuchiya, Kazuhiro; Aoki, Chinatsu; Hachiya, Junichi [Department of Radiology, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka, 181-8611, Tokyo (Japan)

    2004-02-01

    We evaluated the feasibility of MR cisternography by the balanced fast-field-echo (bFFE) sequence, comparing with that by a turbo-spin-echo (TSE) sequence, for cerebellopontine angle lesions on a 1.5-T imager (Gyroscan Intera, Philips, Best, The Netherlands). The bFFE MR cisternograms depicted target cranial nerves with less cerebrospinal fluid pulsation artifacts than TSE cisternograms and visualized an acoustic schwannoma in 6 of 44 patients with suspicion and a causative vessel of hemifacial spasm in all of 3 patients in a short scanning time (1 min 53 s). The bFFE sequence can be promising for MR cisternography in the diagnosis of cerebellopontine angle lesions. (orig.)

  4. Metastatic Adenocarcinoma of Unknown Primary in the Bilateral Cerebellopontine Angles: Case Report and Review of the Literature.

    Science.gov (United States)

    Zhang, Dao-Bao; Zheng, Nian-Dong

    2015-01-01

    Metastatic adenocarcinoma in bilateral cerebellopontine angles (CPA) is rare. We report a case and review the current literature in order to enhance recognition of metastatic adenocarcinoma in the cerebellopontine angle. A 44-year-old man was referred to the hospital with rightsided diminished hearing for 7 weeks, left-sided facial palsy for 2 weeks, and left-sided sensorineural hearing loss for 1 week. On Magnetic Resonance Imaging (MRI) two tumors in bilateral CPAs were detected. The left-sided tumor was resected and histopathological examination revealed an adenocarcinoma. Many investigations could not find the primary tumor. One should be careful with middle-aged or elderly patients with sudden progressive deficits in the VIII th or VII th cranial nerves, particularly in bilateral CPA. PMID:26617145

  5. Primary Intracranial Malignant Nerve Sheath Tumor in the Cerebellopontine Angle in a Woman with Neurofibromatosis Type 2

    OpenAIRE

    Bita Geramizadeh; Mehrzad Pourjafar; Ramin Mardani; Negar Azarpira; Saeid Farokhi

    2009-01-01

    Neurofibromatosis type 2 is an inherited disease. The mainmanifestation of the disease is the development of symmetric,non-malignant brain tumors in the region of the cranial nerveVIII usually as schwannoma. We report here a 20-year-oldwoman with primary intracranial malignant nerve sheath tumorlocated in the left cerebellopontine angle. Histologically, the tumorshowed malignant spindle cells in fascicular pattern withfocal S100 positivity on immunohistochemistry. A subtotal surgicalresection...

  6. Intraoperative Transcranial Motor-Evoked Potential Monitoring of the Facial Nerve during Cerebellopontine Angle Tumor Resection.

    Science.gov (United States)

    Cosetti, Maura K; Xu, Ming; Rivera, Andrew; Jethanamest, Daniel; Kuhn, Maggie A; Beric, Aleksandar; Golfinos, John G; Roland, J Thomas

    2012-10-01

    Objective To determine whether transcranial motor-evoked potential (TCMEP) monitoring of the facial nerve (FN) during cerebellopontine angle (CPA) tumor resection can predict both immediate and long-term postoperative FN function. Design Retrospective review. Setting Tertiary referral center. Main Outcome Measures DeltaTCMEP (final-initial) and immediate and long-term facial nerve function using House Brackmann (HB) rating scale. Results Intraoperative TCMEP data and immediate and follow-up FN outcome are reported for 52 patients undergoing CPA tumor resection. Patients with unsatisfactory facial outcome (HB >2) at follow-up had an average deltaTCMEP of 57 V, whereas those with HB I or II had a mean deltaTCMEP of 0.04 V (t = -2.6, p  2) facial function in the immediate postoperative period. Conclusion Intraoperative TCMEP of the facial nerve can be a valuable adjunct to conventional facial nerve electromyography during resection of tumors at the CPA. Intraoperative deltaTCMEP >57 V may be worrisome for long-term recovery of satisfactory facial nerve function. PMID:24083121

  7. Benign and malignant lesions in the region of the inner ear and cerebellopontine angle; Benigne und maligne Veraenderungen der Innenohr- und Kleinhirnbrueckenwinkelregion

    Energy Technology Data Exchange (ETDEWEB)

    Czerny, C.; Nemec, S.; Krestan, C. [Medizinische Universitaet Wien (Austria). Klinik fuer Radiodiagnostik; Gstoettner, W. [Universitaetsklinikum Frankfurt am Main (Germany). Klinik fuer HNO-Erkrankungen

    2006-03-15

    Tumorous lesions in the region of the inner ear and cerebellopontine angle are very rare and can be classified into benign and malignant disease forms. This contribution presents and explains the CT and MRI characteristics of these tumors. High-resolution computed tomography (HRCT) in the axial projection is applied for evaluation in the high-resolution bone window. The coronary slices can be reconstructed from the axial datasets or in individual cases examined in the coronary plane. HRCT excellently demonstrates osseous lesions and in individual cases - e.g., exostoses - it can simply suffice to perform HRCT of the temporal bone, while HRCT is also excellent for detecting osseous lesions to determine whether the tumor is benign or malignant. MRI, on the other hand, excellently shows the extent of tumor spread because of its superb soft tissue contrast. Consequently, HRCT and MRI images of the inner ear and cerebellopontine angle provide meaningful information for visualization and classification of tumorous lesions. The two methods should not be considered as competing but rather as complementary and among other aspects exert considerable influence on the therapeutic approach. (orig.) [German] Tumoroese Veraenderungen der Innenohr- und Kleinhirnbrueckenwinkelregion sind sehr selten und koennen in benigne und maligne Erkrankungen eingeteilt werden. In dieser Arbeit sollen die CT- und MRT-Charakteristika dieser Tumoren erlaeutert und dargestellt werden. Die hochaufloesende Computertomographie (HRCT) kommt in axialer Schichtfuehrung, in der Auswertung im hochaufloesenden Knochenfenster, zum Einsatz. Die koronalen Schichten koennen aus den axialen Datensaetzen rekonstruiert oder in einzelnen Faellen in koronaler Ebene untersucht werden. Die HRCT zeigt exzellent die knoechernen Veraenderungen, und es kann in Einzelfaellen - wie z. B. bei Exostosen - genuegen, lediglich eine HRCT des Schlaefenbeins anzufertigen, waehrend auch mit der HRCT exzellent Knochenveraenderungen

  8. MRI of the cerebellopontine angle in patients with cleido-cranial dysostosis; MRT der Kleinhirnbrueckenwinkelregion bei Patienten mit Dysostosis cleido-cranialis

    Energy Technology Data Exchange (ETDEWEB)

    Scherer, A.; Engelbrecht, V.; Nawatny, J.; Moedder, U. [Duesseldorf Univ. (Germany). Inst. fuer Diagnostische Radiologie; Messing-Juenger, M. [Duesseldorf Univ. (Germany). Neurochirurgische Klinik; Reifenberger, G. [Duesseldorf Univ. (Germany). Inst. fuer Neuropathologie

    2001-04-01

    Purpose: Cleidocranial dysostosis (CCD) is an autosomal dominant bone disorder in which deafness is common secondary to malformation of the middle ear structures. The study aimed at MRI evaluation of the cerebellopontine angle in 7 patients with a history of CCD - two generation spanned relatives. Material and methods: Cranial MRI in 7 patients with CCD (4 women/3 men aged between 8 and 46 years) was performed. In two patients hearing disorders were present. The examinations encompassed multi-planar spinecho sequences of the cerebellopontine angle in 3-mm slice thickness before and after administration of contrast medium. Results: The clinically most conspicuous female patient (hearing loss, ataxia, headache) showed a strongly contrast-enhancing tumor in MRI that was histologically proved to be an acoustic schwannoma. Concerning the other family members, no pathological findings were noted except for non-pneumatized mastoids. Conclusion: The first report of a patient with CCD and an acoustic schwannoma shows that in case of hearing loss in these patients also a retrocochlear cause must be considered. (orig.) [German] Ziel: Die Dysostosis cleido-cranialis (DCC) ist eine autosomal-dominant erbliche Knochenerkrankung, bei der aufgrund von Mittelohrmissbildungen gehaeuft Hoerstoerungen beobachtet werden. Wir ueberpruefen bei 7 von diesem Syndrom betroffenen Verwandten 1. und 2. Grades, ob sich kernspintomographisch Auffaelligkeiten der Kleinhirnbrueckenwinkelregion nachweisen lassen. Material und Methoden: MRT-Untersuchungen des Schaedels bei 7 Patienten mit DCC (4 Frauen, 3 Maenner im Alter zwischen 8 und 46 Jahren). Bei zwei Patienten lagen klinisch Hoerstoerungen vor. Die Bildgebung umfasste multiplanare Spin-Echo-Sequenzen und wurde im Bereich des Kleinhirnbrueckenwinkels in 3 mm Schichtdicke vor und nach Gadoliniumgabe durchgefuehrt. Ergebnisse: Die klinisch auffaelligste Patientin (progredienter Hoerverlust, Ataxie, Cephalgien) zeigte in der MRT einen kraeftig

  9. Neuro-otological findings and CT scanning of cerebellopontine angle tumors

    International Nuclear Information System (INIS)

    Clinical evaluation was carried out on 13 cerebellopontine angle tumors which consisted of ten acoustic neuromas, two meningiomas and one facial nerve neurinoma. The relationship among the neurootological findings and CT scaning findings and gross appearance of the tumors were summarized as follows: 1) Many acoustic neuromas had initial symptoms of hearing loss associated with equilibrium disturbance and/or gait disturbance at the time of diagnosis of tumors. As further increase in tumor size occurs, the patients tended to complain of a great variety of neurologic symptoms and nystagmus. With further enlargement in tumor size, appearance rate of abnormality in OKP test and ETT tended to be higher. 2) The acoustic neuromas which consisted mostly of cystic mass tended to show less hearing loss and nystagmus than those which consisted mostly of solid mass. 3) Caloric response appeared abnormal in all cases of acoustic neuroma. 4) In all cases of acoustic neuroma, Stenvers view and frontal tomographic sections of petrous pyramids showed enlargement of the internal audiotory canal. Plain CT scanning of acoustic neuromas tended to reveal iso-density or low density area. Contrast enhanced CT scanning tended to reveal ring-like high density area. Acoustic neuroma with ring-like high density on the CT scanning consisted of not only cystic mass but also solid mass. 5) In cases of meningioma and facial nerve neuroma, neuro-otological findings were scanty. 6) In ABR, none of the patients showed response or the presense of wave I only or waves I and II or the abnormality of interaural latency difference. (author)

  10. Bilateral hypertrophic olivary degeneration following surgical resection of a posterior fossa epidermoid cyst

    OpenAIRE

    Vaidhyanath, R; Thomas, A; MESSIOS, N

    2010-01-01

    Hypertrophic olivary degeneration is a result of a primary lesion damaging the dento-rubro-olivary pathway. It is a transynaptic form of degeneration and is unique, causing hypertrophy rather than atrophy of the inferior olivary nucleus. We report a case of bilateral hypertrophic olivary degeneration following surgical excision of a posterior fossa epidermoid cyst and review the relevant literature.

  11. Radiotherapy for Epidermoid Carcinoma of the Anus: Thirty Years' Experience

    International Nuclear Information System (INIS)

    Purpose: To evaluate the factors associated with disease control and morbidity after radiotherapy for anal carcinoma. Methods and Materials: Between 1975 and 2005, 194 patients with localized epidermoid anal carcinoma underwent radiotherapy. Treatment evolved from radiotherapy with or without surgery, to preoperative chemoradiotherapy, to definitive chemoradiotherapy (CRT). The radiotherapy techniques also evolved. Results: With a median follow-up of 61 months, 57 patients had persistence or recurrence, 9 of whom were successfully salvaged, resulting in 146 (75%) ultimately free of disease (UNED). Univariate analysis for UNED survival showed a strong association with the T and N stage (5-year UNED rate, 88.5% ± 3.4% for those with Stage T1-T2N0; 70.1% ± 4.2% for Stage T3N0; and 52.7% ± 6.6% for Stage III; p > .001) and mobility on palpation (5-year UNED rate, 89.2% ± 4.6% for those with mobile tumors vs. 59.3% ± 6.1% for those with tethered/fixed tumor; p > .001). No association was found with gender, age, preoperative vs. definitive CRT, or human immunodeficiency virus status. The 20 human immunodeficiency virus+ patients all received CRT. The radiotherapy factors associated with Grade 3 or greater late morbidity included anorectal morbidity with tumor dose (29% with a dose ≥55 Gy vs. 9% otherwise), small bowel injury with technique (9% with anteroposterior-posteroanterior supine vs. 0.7% with multiple fields prone), and bone injury with femoral head dose (9% with a dose of ≥44 Gy vs. 0.7% otherwise). Of the 194 patients, 56 had 68 additional malignancies, mainly either antedating the anal cancer or outside the radiation fields. Conclusion: Our results have confirmed that CRT is an effective approach. Patients with human immunodeficiency virus can be treated with CRT. Tumor mobility significantly predicts the outcome; the implications for management are discussed. We also discuss the treatment planning implications of the late morbidity findings. The

  12. Presentations

    International Nuclear Information System (INIS)

    The presented materials consist of presentations of international workshop which held in Warsaw from 4 to 5 October 2007. Main subject of the meeting was progress in manufacturing as well as research program development for neutron detector which is planned to be placed at GANIL laboratory and will be used in nuclear spectroscopy research

  13. Presentations

    International Nuclear Information System (INIS)

    The PARIS meeting held in Cracow, Poland from 14 to 15 May 2007. The main subjects discussed during this meeting were the status of international project dedicated to gamma spectroscopy research. The scientific research program includes investigations of giant dipole resonance, probe of hot nuclei induced in heavy reactions, Jacobi shape transitions, isospin mixing and nuclear multifragmentation. The mentioned programme needs Rand D development such as new scintillations materials as lanthanum chlorides and bromides as well as new photo detection sensors as avalanche photodiodes - such subjects are also subjects of discussion. Additionally results of computerized simulations of scintillation detectors properties by means of GEANT- 4 code are presented

  14. Presentation

    OpenAIRE

    Eduardo Vicente; Rosana de Lima Soares; Eduardo Victorio Morettin

    2013-01-01

    In the present edition of Significação – Scientific Journal for Audiovisual Culture and in the others to follow something new is brought: the presence of thematic dossiers which are to be organized by invited scholars. The appointed subject for the very first one of them was Radio and the invited scholar, Eduardo Vicente, professor at the Graduate Course in Audiovisual and at the Postgraduate Program in Audiovisual Media and Processes of the School of Communication and Arts of the University ...

  15. Presentation

    Directory of Open Access Journals (Sweden)

    Paulo Henrique Freire Vieira

    2013-12-01

    Full Text Available This dossier focuses on one of the essential debate topics today about the territorial dimension of the new development strategies concerned with the worsening of the global socioecological crisis, that is: the challenges related to the activation and integration in networks of localized agri-food systems. For its composition, some contributions presented and debated during the VI International Conference on Localized Agri-food System - The LAFS facing the opportunities and challenges of the new global context have been gathered. The event took place in the city of Florianópolis, from May 21th to 25th of 2013. The event was promoted by the Federal University of Santa Catarina (UFSC and by the Center for the International Cooperation on Agricultural Research for Development (CIRAD. Besides UFSC and CIRAD, EPAGRI, State University of Santa Catarina (UDESC, as well as research institutes and universities from other states (UFMG, IEA/SP, UFS, UFRGS and Mexican and Argentinian partners from the RED SIAL Latino Americana also participated in the organization of lectures, discussion tables and workshops.

  16. Presentation

    Directory of Open Access Journals (Sweden)

    Isidor Marí Mayans

    2004-04-01

    Full Text Available As was the case at the conference, "Humanities professions in the knowledge society", the Director of Humanities and Philology Studies at the UOC, Isidor Marí, presents this Dossier, and the subsequent virtual debate, with the aim of gaining useful conclusions, with specific repercussions on the organisation of the degree studies and its professional projection, especially at this time, which requires study plans to be redesigned in line with the Bologna process. In the author's opinion, we can only make the right operative decisions when we are able to understand the transformations taking place in the humanistic culture framed by the knowledge society, and to do so, debate has to be opened in which students, graduates, academics, researchers, professionals and analysts can all take part.In this article, Isidor Marí analyses the tensions and contradictions that arise when attempts are made to relate the concepts of the professional world, Humanities and the knowledge society. Firstly, neither are Humanities a profession nor the study of Humanities seen by students or society to be adaptable to the definition of professional profiles. However, this highlights an important paradox, as the culture economy, (and, thus, occupations in the cultural sector, is growing increasingly throughout western societies. Likewise, in terms of the relationship between Humanities and the knowledge society, the author describes and analyses how there currently coexist voices foreseeing the worst alongside those that see information and communications technologies opening the way for an enormously positive transformation in human civilisation and a new cultural era.

  17. Presentation

    Directory of Open Access Journals (Sweden)

    Eduardo Vicente

    2013-06-01

    Full Text Available In the present edition of Significação – Scientific Journal for Audiovisual Culture and in the others to follow something new is brought: the presence of thematic dossiers which are to be organized by invited scholars. The appointed subject for the very first one of them was Radio and the invited scholar, Eduardo Vicente, professor at the Graduate Course in Audiovisual and at the Postgraduate Program in Audiovisual Media and Processes of the School of Communication and Arts of the University of São Paulo (ECA-USP. Entitled Radio Beyond Borders the dossier gathers six articles and the intention of reuniting works on the perspectives of usage of such media as much as on the new possibilities of aesthetical experimenting being build up for it, especially considering the new digital technologies and technological convergences. It also intends to present works with original theoretical approach and original reflections able to reset the way we look at what is today already a centennial media. Having broadened the meaning of “beyond borders”, four foreign authors were invited to join the dossier. This is the first time they are being published in this country and so, in all cases, the articles where either written or translated into Portuguese.The dossier begins with “Radio is dead…Long live to the sound”, which is the transcription of a thought provoking lecture given by Armand Balsebre (Autonomous University of Barcelona – one of the most influential authors in the world on the Radio study field. It addresses the challenges such media is to face so that it can become “a new sound media, in the context of a new soundscape or sound-sphere, for the new listeners”. Andrew Dubber (Birmingham City University regarding the challenges posed by a Digital Era argues for a theoretical approach in radio studies which can consider a Media Ecology. The author understands the form and discourse of radio as a negotiation of affordances and

  18. Porfiromycin in the management of epidermoid and transitional cell cancer: a phase II study.

    Science.gov (United States)

    Panettiere, F J; Talley, R W; Torres, J; Lane, M

    1976-07-01

    Porifiromycin has been tested in many groups of patients over the past several years (1-7). This report is an analysis of greater than 100 patients with epidermoid and urinary tract transitional cell carcinomas treated with this agent. A review of these data and the available literature on this agent shows that porfiromycin offers definite usefulness in disseminated squamous cell carcinomas of the cervix, and definite but lesser effectiveness in epidermoid carcinomas of the lung, the head and neck region, and other sites. Responsiveness was also demonstrated in transitional cell carcinomas of the urinary tract. Toxicity was tolerable and consisted primarily of myelosuppression and local skin necrosis in sites where extravasation had occurred. PMID:795539

  19. Presentation

    Directory of Open Access Journals (Sweden)

    Nicanor Lopes

    2010-11-01

    Full Text Available The Journal Caminhando debuts with a new editorial format: eachmagazine will have a Dossier.In 2010 Christianity celebrated the centenary of Edinburgh. TheWorld Missionary Conference in Edinburgh in 1910 is regarded by manyas missiological watershed in the missionary and ecumenical movement.So the Faculty of Theology of the Methodist Church (FATEO decidedto organize a Wesleyan Week discussing the issue of mission. For anevent of this magnitude FATEO invited the Rev. Dr. Wesley Ariarajah,Methodist pastor and teacher of Sri Lanka with extensive experience inpastoral ministry in local churches and professor of History of Religionsand the New Testament at the Theological College of Lanka, maintainedby the Protestant Churches in Sri Lanka. In 1981 he was invited to jointhe World Council of Churches, where he presided for over ten years theCouncil of Interreligious Dialogue. From 1992 he served as Deputy GeneralSecretary of the WCC.The following texts are not the speeches of the Rev. Dr. WesleyAriarajah, for they will be published separately. Nevertheless, the journaldialogs with the celebrations of the centenary of Edinburgh, parting formthe intriguing theme: "Mission in the 21st century in Brazil". After all, howis it that mission takes place among us in personal, church, and communityactivities?Within the Dossier, as common to the journal, the textos are organizedas follows: Bible, Theology / History and Pastoral Care. Other items thatdo not fit within the Dossier, but, do articulate mission, can be found inthe section Declarations and Documents and Book Reviews.The authors of the Dossier have important considerations in buildinga contemporary missiological concept considering Brazilian reality.Anderson de Oliveira, in the Bible-Section, presents a significantexegeses of Matthew 26.6-13. What does it mean when Jesus is quotedwith the words: "For the poor always ye have with you, but me ye havenot always." Is this declaration challenging the gospels

  20. Prognostic significance of s-phase fraction detected by antithymidine antibodies in epidermoid cervix carcinomas

    International Nuclear Information System (INIS)

    Purpose: To assess the predictive value of pretreatment proliferative activity of epidermoid cervix carcinoma cells with respect to short- and long-term results of radiotherapy. Methods and Materials: The proliferative activity of 25 epidermoid cervix carcinomas was evaluated as the immunofluorescent labelling index (LI) by rabbit antithymidine antibodies reacting specifically with single-stranded DNA of replication forks in S-phase cells. The short-term clinical outcome was estimated at 3-6 months after treatment by visual and palpatory examination. Three-year follow-up data were obtained through hospital charts and correspondence with referring physicians for only 19 patients. Results: There was no statistically significant association between LI and such conventional prognostic factors as clinical stage. The LI value of cervix carcinomas was significantly associated with complete regression at 3-6 months after radiotherapy and 3-year disease-free survival. Complete regression at 3-6 months was observed in 87.5% patients with fast proliferating tumors (LI > 7.0%), and only in 41.2% patients with slowly proliferating tumors (p = 0.03). Probability of 3-year disease-free survival was 85.7% in patients with fast proliferating tumors and 50.0% in those with slowly proliferating tumors (p = 0.05). Conclusions: The immunofluorescent LI of epidermoid cervix carcinoma is able to provide prognostic information on short-term tumor response to radiotherapy and disease-free survival

  1. Radiosurgery of epidermoid tumors with gamma knife. Possiblity of radiosurgical nerve decompression

    International Nuclear Information System (INIS)

    Long-term results of radiosurgery for epidermoid tumors are reported. There are 7 cases including 2 males and 5 females, ages ranging from 6 to 46 (mean: 33.3 years). At radiosurgery whole tumor was covered in 4 cases and partially covered in 3 cases in attempting to relieve cranial nerve signs like trigeminal neuralgia and facial spasm. The mean maximum and marginal doses were 25.6 Gy and 14.6 Gy respectively. In the mean follow-up of 52.7 months, all the tumors showed good tumor control without any progression and tumor shrinkage has been confirmed in 2 out of the 7 cases. Symptomatic trigeminal neuralgia improved or disappeared in all 4 cases and facial spasm disappeared in one. No neurological deterioration was found in any of the cases after the treatment. In conclusion, it is apparent that epidermoid tumors do respond well to radiosurgery and the accompanying hyperactive dysfunction of cranial nerves is significantly improved by gamma knife treatment with either entire or partial tumor coverage. Therefore the radiosurgical nerve decompression for epidermoid tumor seems to be achieved by gamma-radiosurgery. (author)

  2. Radiopertechnetate flow study: a valuable adjunct to brain scanning in the differential diagnosis of cerebello-pontine angle tumors

    International Nuclear Information System (INIS)

    Twenty-seven surgically proven acoustic neuromas were studied preoperatively with conventional brain scanning. Nine lesions were not diagnosed. Lesions less than 2.0 cm in diameter were not visualized (five patients). Lesions larger than 3.0 cm were all detected (15 patients). Lesions ranging in size from 2.0 to 3.0 cm were detected half of the time (six patients, seven lesions). Fourteen/sup 99m/Tc-pertechnetate flow studies were performed in 10 patients with acoustic neuromas. All were negative. A case of meningioma in the cerebello-potine angle and a case of arteriovenous malformation in the posterior fossa were visualized on conventional scan. The flow studies were positive and demonstrated patterns suggestive of the nature of the lesions. Flow study appears a valuable adjunct to brain scanning in the differential diagnosis of cerebello-pontine angle tumors

  3. Epidermoid bronchogenic carcinoma in a 21 year old black man Carcinoma broncogénico epidermoide en un hombre de 21 años

    Directory of Open Access Journals (Sweden)

    Dianelisa De La Hoz Rodríguez

    1999-01-01

    Full Text Available A 21 year cid black man, native from Chocó (Colombia, variously employed, who presented with a respiratory difficulty syndrome of two months of evolution, right pleuritic pain, congestive cardiac failure and systemic symptoms. A homogeneic white .grayish tumor measuring 8 by 10 cm with necrotic areas was found at necropsy. The tumor originated in the main bronchial tube of the lower and middle lobes of the right lung and invaded the entire pericardial vicinity forming a cuirass and causing tumoral constrictive pericarditis. Microscopic studies revealed a well differentiated squamous type bronchogenic carcinoma. Bronchogenic carcinomas are frequently associated with cigarette smoking. However, their incidente has increased among non. smokers, suggesting the possibility that there are other causal factors, such as atmospheric contaminants, genetic predisposition, diets deficient in vitamin A and carotene, presente of certain viruses and immunologic changes. Lung cancer constitutes 16% among the types of cancer suffered by men and 13% among women, it has its greatest incidente in groups between 40 and 70 years of age and only 1 to 5 percent of thecasesoccur in groupsunder theageofforty years. Hombre de 21 años de edad de raza negra, natural del Chocó (Colombia, quien ha desempeñado diversos oficios; presentó un síndrome de dificultad respiratoria de dos meses de evolución, dolor pleurítico derecho, insuficiencia cardíaca congestiva y síntomas sistémicos. En la necropsia se encontró una masa tumoral blanco-grisácea de 10 x 8 cm, homogénea, con áreas de necrosis, originada en el bronquio principal de los lóbulos inferior y medio derechos y que invadió por vecindad en forma de coraza todo el pericardio causando una pericarditis constrictiva tumoral. El estudio microscópico correspondió a un carcinoma broncogénico tipo epidermoide bien diferenciado. El carcinoma broncogénico se asocia frecuentemente con el consumo de cigarrillo

  4. Tumores dermóides e epidermóides intra-espinhas Intraspinal epidermoid and dermoid tumours

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    Oscar Fontenelle Filho

    1971-03-01

    Full Text Available São relatados dois casos de tumores epidermóides e um de tumor dermóide, todos intrarraquianos. Este último era de localização epidural ao nível da coluna torácica (caso 3; os dois tumores epidermóides situavam-se na coluna tóraco-lombar (caso 1 e lombar (caso 2, respectivamente, sendo o primeiro intramedular e o segundo intradural. Em dois casos (casos 2 e 3 os tumores associavam-se a fístula dérmica congênita. Um paciente (caso 3 foi operado aos dois meses de idade; a descoberta do tumor deveu-se à realização da raquimanometria que revelou bloqueio, apesar do paciente não apresentar qualquer sinal neurológico de compressão medular. Os autores são de opinião que, em presença de fístula dérmica congênita ao nível da coluna vertebral, principalmente quando localizada acima do segmento lombosacro, deve-se sempre suspeitar da possibilidade do tumor epidermóide ou dermóide intrarraquiano, mesmo na ausência de sinais neurológicos. A combinação de sintomas neurológicos de longa duração, a evidência radiológica de erosão e alargamento do canal raquiano e a história de fístula dérmica congênita proporcionaram o diagnóstico pré-operatório correto no caso 2.Two cases of epidermoids and one case of dermoid intraspinal tumours are reported. The last case was located at thoracic level (T7 (case 3 and was epidural in localization. The two epidermoids tumours were located at the thoracic-lumbar (case 1 and lumbar (case 2 level, respectively; the first was intramedullary and the second subdural in localization. In two (cases 2 and 3 there was associated communicating pilonidal sinuses. One of the patients (case 3 was operated within the second month of age. The early discovery of the tumour in this patient was made through a lumbar raquimanometry that disclosed a complete subarachnoid block. In spite of this the patient did not presented any neurological symptoms. The authors are of opinion that in presence of a

  5. Induction chemotherapy and radiotherapy in loco-regionally advanced epidermoid carcinoma of the anal canal

    International Nuclear Information System (INIS)

    recurrence (Relative risk .3, P = .02) but not for any other endpoint. CONCLUSION: This regimen with IC + RT ± surgery is well tolerated and yields treatment results that are encouraging for loco-regionally advanced epidermoid anal carcinoma, with good chances for long term survival and preservation of sphincter function. A well designed randomized multicentric trial is needed to further elucidate the role of induction chemotherapy in the treatment of anal carcinoma. The results of the present study may be of use in dimensioning such a trial

  6. Honokiol, a chemopreventive agent against skin cancer, induces cell cycle arrest and apoptosis in human epidermoid A431 cells.

    Science.gov (United States)

    Chilampalli, Chandeshwari; Guillermo, Ruth; Kaushik, Radhey S; Young, Alan; Chandrasekher, Gudiseva; Fahmy, Hesham; Dwivedi, Chandradhar

    2011-11-01

    Honokiol is a plant lignan isolated from bark and seed cones of Magnolia officinalis. Recent studies from our laboratory indicated that honokiol pretreatment decreased ultraviolet B-induced skin cancer development in SKH-1 mice. The aim of the present investigation was to study the effects of honokiol on human epidermoid squamous carcinoma A431 cells and to elucidate possible mechanisms involved in preventing skin cancer. A431 cells were pretreated with different concentrations of honokiol for a specific time period and investigated for effects on apoptosis and cell cycle analysis. Treatment with honokiol significantly decreased cell viability and cell proliferation in a concentration- and time-dependent manner. Honokiol pretreatment at 50 μmol/L concentration induced G0/G1 cell cycle arrest significantly (P Cdk4 and Cdk6 proteins and up-regulated the expression of Cdk's inhibitor proteins p21 and p27. Pretreatment of A431 cells with honokiol leads to induction of apoptosis and DNA fragmentation. These findings indicate that honokiol provides its effects in squamous carcinoma cells by inducing cell cycle arrest at G0/G1 phase and apoptosis. PMID:21908486

  7. Results of radial therapy epidermoid of lungs cancer with dynamic fractionating dozes

    International Nuclear Information System (INIS)

    Under supervision there were 53 patients epidermoid of lung cancer by which radial therapy under the radical program (Muravskaja G. V. and co author 1998)was carried out . The purpose of work was studying results of radial treatment epidermoid lungs cancer under the radical program and some factors of the prognosis. The diagnosis of epidermoid lungs cancer patients has been confirmed by morphologic. All patients were under supervision more than 1 year.27 from the above stated patients (the first group) 26 patients (the second group)-less than one year lived more than 1 year (51.0%). The two year survival rate of patients of the first group has made 15.1% .Three year survival rate - 11.3% . Results correspond to the literary data(Bauman M.2001)distinction on age was not. At the analysis of distribution of patients on a degree of prevalence of a tumour it is established , that in the first group it was observed: T2NO-4;T2N1-4;T2-3N2,T3NO-1-19,accordingly, in the second group: T2 N0-3,T2N1-2;T2-3N2,T3N1-14;T2-3 N3-7. In both groups prevailed 111 degree of disease:in the first -70,9%,in the second 80.8%. But in group of patients living less than one year, in 26,9% was observed metastatic spreading tumours in the lymphatic nodes, corresponding to category N3. In the second group also much more often are atelectasis, not allowed radiographical to limit a shadow of a tumour from a shadow atelectasis (58.0±9.7% and 30.0±8.8%,p<0.05).Frequency full resorption tumours was observed in the first group in 37.0±9.3%, in the second 3.9±3.8%, almost in 10 times it is less. The received data specify direct correlation between the loco-regional control and lymphogenous distribution epidermoid lungs cancer, presence of atelectasis.In the latter case deterioration of results is probably caused by impossibility at radiological research to define border a tumour and atelectasis that is important at planning volume of irradiation.I n this connection other method of visualization are

  8. Isolated relapse ganglions of epidermoid carcinomas of superior aero-digestive ways:Does the brachytherapy have its place

    International Nuclear Information System (INIS)

    The brachytherapy of isolated ganglions relapses of epidermoid carcinomas allows the ganglions control to three years in 25% of cases. Taking into account its toxicity (6% of deceases) and the unfavorable prognosis of the illness, a cervical ganglion surgery must be always preferred. (N.C.)

  9. Carcinoma epidermoide do pênis: estudo clínico-patológico de 34 casos Squamous cell carcinoma of the penis: clinicopathologic study of 34 cases

    OpenAIRE

    Fabiana Braga França Wanick; Tullia Cuzzi Teichner; Rosane Silva; Mônica Maria Ferreira Magnanini; Lucia Maria Soares de Azevedo

    2011-01-01

    FUNDAMENTOS: No Brasil, a incidência do câncer do pênis é de 8,3 casos/100.000 habitantes, contrastando com 0,7 na Europa e nos Estados Unidos. Em 95% dos casos, trata-se do carcinoma epidermoide. Em geral, é diagnosticado tardiamente. OBJETIVOS: Descrever as características clínico-patológicas do carcinoma epidermoide do pênis, registradas no Hospital entre 1978 e 2004. MÉTODOS: Estudo observacional transversal. Incluíram-se os casos de carcinoma epidermoide do pênis, confirmados histologica...

  10. The modified lateral supraorbital approach for tumors of the petroclival junction extending into the anterior cerebellopontine area.

    Science.gov (United States)

    Lim, Jaejoon; Cho, Kyunggi

    2016-05-01

    Various surgical approaches for the removal of meningioma and trigeminal schwannoma in the petroclival junction (PCJ) and anterior cerebellopontine area (CPA) have been described previously. In this study, we compared the surgical outcomes of the combined petrosal approach and a modified lateral supraorbital (MLSO) approach and evaluated the reliability and safety of the MLSO approach. Fifty patients underwent surgical treatment using the combined petrosal or MLSO approach between 1996 and 2011. We retrospectively analyzed the clinical data and compared the two approaches. Among 50 patients, 27 patients underwent operation through the combined petrosal approach and 23 underwent operation through the MLSO approach. The operation time of the MLSO approach was significantly shorter than that of the combined petrosal approach (p = 0.03). There was no significant difference in the gross total resection rate between the two approaches (p = 0.67). After the operation, the improvement in Karnofsky performance score and Mean Glasgow outcomes scales were better in the MLSO approach, but without statistical significance (p = 0.723, p = 0.20 respectively). Complications occurred more often with the combined petrosal approach than with MLSO. Facial nerve palsy was the most common complication, followed by hearing difficulty. The frequency of these two complications was higher in the combined petrosal approach. Various tumors occurring in the PCJ and anterior CPA remain a challenging problem for neurosurgeons. The new modified approach of MLSO yielded good surgical results for these tumors compared to the combined petrosal approach. Therefore, the MLSO approach might be a good option for removal of tumors in the PCJ including anterior CPA. PMID:26886578

  11. Epidermoids and dermoids of the calvarian bones in early childhood: Their behaviour in the growing skull

    International Nuclear Information System (INIS)

    Thirteen out of 25 cystic lesions of the infantile skull, radiographically classified as epidermoids or dermoids of the calvarian bones, disappeared spontaneously during early childhood. A further six lesions showed involution. In all, 19/25 lesions were involutive. In no case did we find an enlargement which could be attributed with certainly, to growth after the age of 3 years. These findings strongly support the opinion of Faure that by far most of these lesions are non-evolutive and generally do not need surgical treatment. Only lesions which do persist beyond the third year of life and grow continuously or begin to grow again need to be operated. Thus, we recommend a conservative attitude and a radiographic follow-up at long intervals. (orig.)

  12. Pheophorbide a mediated photodynamic therapy against human epidermoid carcinoma cells (A431)

    Science.gov (United States)

    Chen, Yi-Chun; Li, Wen-Tyng

    2011-02-01

    The objective of this study was to characterize the death mechanism of human epidermoid carcinoma cells (A431) triggered by photodynamic therapy (PDT) with pheophorbide a. First of all, significant inhibition on the survival of A431 cells (N-Acetyl cysteine prevented ROS production and increased cell survival thereafter. The decrease in cellular ATP level was also observed at 6 hrs after PDT. Typical apoptotic cellular morphology and a collapse of mitochondrial membrane potential occurred after PDT. The loss of mitochondrial membrane potential led to the release of cytochrome c from the mitochondria to the cytosol, followed by activation of caspase-9 and caspase-3. The activation of caspase-3 resulted in poly(ADP-ribose) polymerase (PARP) cleavage in A431 cells, followed by DNA fragmentation. In conclusion, the results demonstrated that pheophorbide a possessed photodynamic action against A431 cells, mainly through apoptosis mediated by mitochondrial intrinsic pathway triggered by ROS.

  13. Purification of high-molecular-weight subfraction from porcine skin inhibiting proliferation of A431 human carcinoma epidermoid cells.

    Science.gov (United States)

    Belova, O V; Sergienko, V I; Arion, V Ya; Lukanidina, T A; Moskvina, S N; Zimina, I V; Borisenko, G G; Lutsenko, G V; Grechikhina, M V; Kovaleva, E V; Klyuchnikova, Zh I

    2014-07-01

    Subfraction with a molecular weight >250 kDa isolated from porcine skin and inhibiting the proliferation of A431 human carcinoma epidermoid cells was purified by DEAE 32 anion exchange chromatography with NaCl concentration step-gradient. The effects of the initial subfraction and fractions obtained by separation in DEAE 32 on the proliferation of A431 human carcinoma epidermoid cells were studied in vitro in two tests (MTT and fluorescent test). The more sensitive fluorescent test showed the highest inhibitory activity of fraction No. 2 released from the column at 0.15 M NaCl. One major protein component and a series of minor protein components were detected in this fraction by vertical PAAG-SDS electrophoresis. PMID:25070165

  14. Induction of apoptosis and antiproliferative activity of naringenin in human epidermoid carcinoma cell through ROS generation and cell cycle arrest.

    Directory of Open Access Journals (Sweden)

    Md Sultan Ahamad

    Full Text Available A natural predominant flavanone naringenin, especially abundant in citrus fruits, has a wide range of pharmacological activities. The search for antiproliferative agents that reduce skin carcinoma is a task of great importance. The objective of this study was to analyze the anti-proliferative and apoptotic mechanism of naringenin using MTT assay, DNA fragmentation, nuclear condensation, change in mitochondrial membrane potential, cell cycle kinetics and caspase-3 as biomarkers and to investigate the ability to induce reactive oxygen species (ROS initiating apoptotic cascade in human epidermoid carcinoma A431 cells. Results showed that naringenin exposure significantly reduced the cell viability of A431 cells (p<0.01 with a concomitant increase in nuclear condensation and DNA fragmentation in a dose dependent manner. The intracellular ROS generation assay showed statistically significant (p<0.001 dose-related increment in ROS production for naringenin. It also caused naringenin-mediated epidermoid carcinoma apoptosis by inducing mitochondrial depolarization. Cell cycle study showed that naringenin induced cell cycle arrest in G0/G1 phase of cell cycle and caspase-3 analysis revealed a dose dependent increment in caspase-3 activity which led to cell apoptosis. This study confirms the efficacy of naringenin that lead to cell death in epidermoid carcinoma cells via inducing ROS generation, mitochondrial depolarization, nuclear condensation, DNA fragmentation, cell cycle arrest in G0/G1 phase and caspase-3 activation.

  15. Enterococcal cerebellopontine angle abscess in a 12-year-old female

    Directory of Open Access Journals (Sweden)

    Sonavane Alka

    2010-01-01

    Full Text Available Despite advances in imaging and antibiotic treatment, brain abscess is still encountered occasionally. Various aerobic and anaerobic bacteria have been reported as causative agents of brain abscess but only a few cases of enterococcal brain abscesses have been reported. Here we report a case of brain abscess in a 12-year-old female patient, who presented with a history of fever, chills, headache, convulsions since seven days and history of altered sensorium and aphasia since the last two days . The patient had chronic suppurative otitis media of both ears following trauma and presented with ear discharge. The diagnosis of brain abscess was done by computerized tomography scan and the pus was aspirated by left suboccipital burr hole operation. Enterococcus species was cultured from the aspirated pus sample. The patient responded to surgical drainage and antibiotic treatment.

  16. Pneumocephalus in cerebellopontine angle and meningitis secondary to chronic otitis media in a child

    OpenAIRE

    Shailendra Ratre; Yadram Yadav; Sushma Choudhary; Vijay Parihar; Yatin Kher; Ketan Hedaoo

    2015-01-01

    Pneumocephalus is a rare complication of chronic otitis media. Despite its rarity intra-cranial air carries a potential risk of increased intra-cranial pressure or meningitis, which requires immediate therapy. A 10-year-old child presented to us with complaints of fever, headache, vomiting, and decreased hearing from left ear. He had history of left ear discharge since 2 years. Clinical examination revealed neck rigidity and left chronic otitis media. Contrast enhanced computed axial tomograp...

  17. Radiation therapy for epidermoid carcinoma of the anal canal, clinical and treatment factors associated with outcome

    International Nuclear Information System (INIS)

    Background and purpose: In recent years, treatment with combined chemotherapy and radiation has become the standard of care for epidermoid carcinoma of the anus. However, optimal radiotherapy techniques and doses are not well established. Materials and methods: During the period 1975-1997, 106 patients with epidermoid carcinoma of the anal canal underwent radiation therapy. Treatment policies evolved from radiation therapy alone or with surgery, to combined chemotherapy and radiation followed by surgery, to combined chemotherapy and radiation. Results: Overall 74% of patients were NED (no evidence of disease) at last follow-up. The most important clinical correlate with ultimate freedom from disease (includes the contribution of salvage surgery) was extent of disease. The 5-year ultimate freedom from disease was 87±5% for T1/T2N0, 78±10% for T3N0 (15% salvaged by surgery), and 43±10% for either T4N0 or any N+ lesions (P<0.001, Tarone-Ware). There was no difference between planned vs. expectant surgery (5-year ultimate NED: 67±11% planned surgery vs. 73±5% expectant surgery). The most important correlate with late toxicity was a history of major pelvic surgery (surgical vs. non-surgical group: P=0.013, Fisher's exact test, two-tailed summation). Thirty-three additional malignancies have been seen in 26 patients. The most common additional malignancies were gynecologic (nine cases), head and neck (six cases), and lung cancer (five cases). Conclusions: For T1/T2N0 disease, moderate doses of radiation combined with chemotherapy provided adequate treatment. T4N0 and N+ lesions are the most appropriate candidates for investigational protocols evaluating dose intensification. T3N0 tumors may also be appropriate for investigation; however, dose intensification may ultimately prove counterproductive if the cure rate is not improved and salvage surgery is rendered more difficult. The volume of irradiated small bowel should be minimized for patients who have a past

  18. Air cisternography of the cerebellopontine angle using high-resolution computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, D.W.

    1984-05-01

    While high-resolution CT/air cisternography is considered the preferred method of investigating non-enhancing or small acoustic neuromas, it is not without pitfalls. Eight such studies were reviewed, emphasizing procedural problems and sources of interpretive error. Two patients presented difficulty in transporting the air bolus due to a spinal cord tumor coexisting with bilaterial acoustic neuromas; spinal cord decompression was required in one case. Three potential false positives were avoided by persistent efforts to fill the internal auditory canal. Of 4 patients thought to have a tiny acoustic neuroma, elective vestibular nerve section in 2 revealed no evidence of tumor.

  19. Combination of radiotherapy and cetuximab for patients suffering from of an advanced and non operable epidermoid carcinoma of the ORL sphere: results and side effects; Association de radiotherapie et de cetuximab chez des patients atteints d'un carcinome epidermoide de la sphere ORL evolue non operable: resultats et effets secondaires

    Energy Technology Data Exchange (ETDEWEB)

    Acevedo, C.; Valette, G.; Bouchekoua, M.; Marianowski, R.; Pradier, O. [CHU Morvan, 29 - Brest (France)

    2010-10-15

    The authors report a retrospective survey of a set of locally advanced epidermoid carcinomas treated by irradiation and cetuximab. They assessed the response to the treatment, the specific survival, and the global survival as well as the tolerance. The survey is based on 31 men and 5 women suffering from different stage 4 non-metastatic advanced epidermoid carcinomas of the ORL sphere. Short communication

  20. Trigeminal Neuralgia Caused by Cerebellopontine Angle Arteriovenous Malformation Treated With Gamma Knife Radiosurgery.

    Science.gov (United States)

    Işik, Semra; Ekşi, Murat Şakir; Yilmaz, Baran; Toktaş, Zafer Orkun; Akakin, Akin; Kiliç, Türker

    2016-01-01

    Trigeminal neuralgia is a facial pain syndrome characterized as sudden onset and lightening-like sensation over somatosensorial branch(es) of fifth cranial nerve. Rarely, some underlying diseases or disorders could be diagnosed, such as multiple sclerosis, brain tumors, and vascular malformations. The authors present a 47-year-old man with trigeminal neuralgia over left V2 and V3 dermatomes. He had a previous transarterial embolization and long use of carbamazepine with partial response to treatment. Gamma knife radiosurgery (GKR) was planned. A marginal dose of 15 Gy was given to 50% isodose line. His pain was relieved by GKR in 1.5 years. Treatment of posterior fossa arteriovenous malformations causing trigeminal neuralgia, with GKR has a very limited use in the literature. It, however, is obvious that success rate as pain relief, in a very challenging field of functional neurosurgery, is satisfactory. Large series, however, are in need to make a more comprehensive statement about efficacy and safety of the procedure in these pathologies. PMID:26674920

  1. Detection of Protein BCL2/JH Rearrangement in Epidermoid Carcinomas of Mouth and Pharynx

    Directory of Open Access Journals (Sweden)

    Montovani, Jair

    2010-09-01

    Full Text Available Introduction: The BCL2 protein found in the internal mothocondrial membrana regulates the apoptosis preventing the programmed cell death. The translocation (14:18, detected in 70 to 85% of the follicular lymphoma, lead the super expression of BCL2 protein, by juxtaposition of BCL2 gene to the JH segment of the immunoglobulins' heavy chain gene. However, the found of the BCL2 expression in head and neck carcinoma are contradictious. Objective: To investigate the presence of the translocation (14:18 of the BCL2 gene in head and neck carcinoma. Method: Sixteen DNA samplers were examinated being 13 of squamous cells carcinoma (SCC and 3 of epidermoid (CE, y means of chain reaction of the polymerase (PCR. Results: The BCL2/JH rearrangement in 2 (15% of the CCE 13 cases and in none of the 3 cases of CE. The average of the frequency of molecules with rearrangement was 46,44x107. Was not observed association between the rearrangement presence and the exhibition to tobacco and alcohol (p=0, 6545. Conclusion: Different from the results found in follicular lymphoma, the presence of the translocation (14; 18 in head and neck carcinomas is not common and, when it occurs, it can be an occasional mutation not associated to exhibition to the tobacco and alcohol.

  2. Phosphorylation of chloroform soluble compounds in plasma membranes of human epidermoid carcinoma A431 cells

    International Nuclear Information System (INIS)

    This study investigated a possible role for the epidermal growth factor (EGF) receptor protein tyrosine kinase in phosphoinositide metabolism with plasma membrane vesicles from human epidermoid carcinoma (A431) cells. The authors found a novel chloroform-soluble product radiolabeled with [gamma-32P]ATP that did not migrate from the origin in the thin layer system designed to separate the phosphoinositides, appeared as a single band of Mr = 3500 on polyacrylamide gels in the presence of dodecyl sulfate, had an ultraviolet absorbance spectrum with a maximum at 275 nm and stained with Coomassie dye. Based on these properties this phosphorylation product is referred to as a proteolipid. The 32P label was not detected in phosphotyrosine [Tyr(P)], phosphoserine [Ser(P)] or phosphothreonine [Thr(P)] and was lost during acid or base hydrolysis. Phosphorylation of proteolipid was increased significantly by EGF, whereas phosphorylation of phosphatidic acid was decreased and labeling of phosphoinositides was unaffected. Thus, it appears that in A431 membranes the EGF receptor/kinase does not utilize phosphatidylinositol as a substrate, but does phosphorylate a membrane proteolipid

  3. Induction chemotherapy and radiotherapy in loco-regionally advanced epidermoid carcinoma of the anal canal

    International Nuclear Information System (INIS)

    Purpose: To evaluate the efficacy of induction chemotherapy in combination with radiotherapy for treatment of loco-regionally advanced epidermoid anal carcinoma. Methods and Materials: Thirty-one patients diagnosed during the period 1989-1994 with loco-regionally advanced cancer of the anal canal (PHITmax ≥ 4 cm or T4 or N+) were treated with induction chemotherapy consisting of one to three courses of carboplatin (300-375 mg/m2 i.v.) and 5-fluorouracil [5,000 mg/(m2 x 120 h) i.v.] followed by external beam irradiation ± surgery. Results: The toxicity of the chemotherapy was low. Twenty-nine patients were tumor free after the primary therapy. Kaplan-Meier analyses were made for overall survival, tumor-specific survival, freedom from recurrence, preservation of sphincter, and event-free survival. For these end points the 5-year data were 67, 85, 80, 69, and 51%, respectively. Conclusion: The results are promising but a well-designed randomized trial is needed to further elucidate the role of induction chemotherapy in the treatment of loco-regionally advanced anal carcinoma

  4. Intraparenchymal epidermoid cysts in the brain: diagnostic value of MR diffusion-weighted imaging

    Energy Technology Data Exchange (ETDEWEB)

    Hu, X.-Y. [Medical Imaging Center, The First Affiliated Hospital of Suzhou, Jiangsu Province (China); Hu, C.-H. [Imaging Center, Soochow University (China)], E-mail: wpdrhxy@hotmail.com; Fang, X.-M.; Cui, L.; Zhang, Q.-H. [Medical Imaging Center, The First Affiliated Hospital of Suzhou, Jiangsu Province (China)

    2008-07-15

    Aim: To evaluate the value of magnetic resonance (MR) diffusion-weighted imaging (DWI) and apparent diffusion coefficients (ADC) maps in the diagnosis of intraparenchymal epidermoid cysts (ECs). Materials and methods: Six cases of histopathologically proven intraparenchymal ECs were studied. All patients were examined with conventional MR (T1WI, T2WI, contrast-enhanced T1WI) and DWI sequences. Along with the mean ADC values (mADC) of the ECs, the cerebrospinal fluid (CSF) and grey matter (GM) were measured. Qualitative and quantitative assessments, as well as MRI findings, were retrospectively analysed using a double blind method by three radiologists in consensus. Results: Four lesions were located in the cerebellum, among them, one was accompanied by an arachnoid cyst; one huge lesion crossed the parenchyma of the frontal and temporal lobes; the other was located in the left temporal lobe. Two lesions had a homogeneous CSF-like intensity on both T1WI and T2WI. The other four were of mixed-intensity on both T1WI and T2WI. All lesions were strikingly hyperintense on DWI, and iso- or slightly hypointense on ADC (relative to the brain). The mADCs of the ECs were significantly higher than that of GM, but significantly lower than that of CSF. Three cases (3/6) were accurately diagnosed using conventional MR sequences without DWI, but in the remaining three cases, correct diagnosis could only be made with help of DWI. Conclusion: DWI sequences can facilitate the diagnosis of intraparenchymal ECs, thus alerting surgeons of the risk of chemical meningitis at surgery. The MR findings of intraparenchymal ECs are basically as the same as those of extracerebral ECs, but the former is likely to have a mixed signal. The hyperintense signal of ECs on DWI is probably caused by the T2 shine-through effect in tumour tissue.

  5. Iridium-192 curietherapy for T1 and T2 epidermoid carcinomas of the floor of mouth

    International Nuclear Information System (INIS)

    From 1970 to 1986, 117 patients with T1 (47) or T2 (70) epidermoid carcinomas of the floor of the mouth (SCC) were treated by iridium-192 implantation (192 Ir). The dose was prescribed according to the Paris System and varied over those years. Follow-up information was available on 116 patients. There were 46 T1N0, 47 T2N0, and 23 T2N1-3. Neck management varied for the 93 N0 patients consisting of surveillance (24 T1, 17 T2) or elective neck dissection (22 T1:all pN-, 30 T2: 20 pN-, 10 pN+). Cause specific survival rates were 94% for T1N0, 61.5% for T2N0, and 28% for T2N1-3 at 5 years. Primary local control was 93.5%, 74.5%, and 65%, respectively, and 98%, 79%, and 65% after salvage. Patients with gingival extension or a tumor size over 3 cm (T2b) had a local control of 50% (9/18) and 58% (15/26), respectively. Nodal control was 93.5% for Stage I, 85% for Stage II, and 48% for T2N1-3 patients. There was no difference in nodal control with regard to treatment policy for Stage I-II patients. There were few complications including three deaths: two from surgery and one from 192 Ir. Nodal status, tumor size defined as T1, T2a (less than or equal to 3 cm), T2b (greater than 3 cm), and gingival extension were the only independent prognostic factors. The management of T1N0 and T2N0 SCC by 192 Ir to a dose of 65 or 70 Gy, using the Paris System, is recommended for lesions 3 cm or less and without gingival extension

  6. Combined interstitial and external radiotherapy following limited surgery of epidermoid carcinomas of the iral cavity

    International Nuclear Information System (INIS)

    From 1.1.1986 to 31.12.1990 50 patients with epidermoid carcinoma of the floor of the mouth and the mobile tongue (stage T1 18, stage T2 20, stage T3 eight and stage T4 four patients) were treated by surgery, 192-iridium implantation using the plastic tube technique and percutaneous irradiation. Survey was performed as enoral resection (35 patients) or en bloc tumour resection with part of the mandible and flap reconstruction (15 patients). Interstitial therapy was considered as a boost to primary tumour region, the dose given ranged between 16 and 33 Gy. 50 to 60 Gy were applied with external beam radiotherapy. Management of the neck consisted of elective or radical neck dissection followed by external beam radiotherapy (50 to 60 Gy). At 2/1991 median follow-up was 17 (three to 53) months. 35 patients are alive and tumour-free, one patient lives with tumour. 14 patients died, eight patients tumour-related, four patients of intercurrent disease and two patients because of a second primary. Primary local control was 18/18 patients for stage T1, 19/20 patients for stage T2, 7/8 patients T3, 3/4 patients for stage T4. Three patients suffered from nodal recurrences, four patients from distant metastases. Complication rate was acceptable. Soft tissue necrosis occurred in 4/18 patients (T1); 5/20 patients (T2); 3/8 patients (T3) and 1/4 patients (T4). Three patients developed osteoradionecrosis. Our results show that combined modality treatment for tumours of the oral cavity yields high local control with acceptable complication rate. (orig.)

  7. Epidermoid carcinomas of the anal canal treated with definitive radiation therapy in a series of 305 patients; Carcinomes epidermoides du canal anal traites par irradiation a visee curative: a propos de 305 patients

    Energy Technology Data Exchange (ETDEWEB)

    Deniaud-Alexandre, E.; Touboul, E.; Huang, R.; Qu, S.H.; Pene, F.; Schlienger, M. [Hopital Tenon, Service d' Oncologie-Radiotherapie, 75 - Paris (France); Tiret, E.; Parc, R. [Hopital Saint-Antoine, Service de Chirurgie Digestive, 75 - Paris (France); Sezeur, A. [Hopital des Diaconesses, Service de Chirurgie Generale, 75 - Paris (France); Houry, S. [Hopital Tenon AP-HP, Service de Chirurgie Digestive, 75 - Paris (France); Gallot, D. [Groupe Hospitalier Bichat-Claude-Bernard, Service de Chirurgie Generale et Digestive B, 75 - Paris (France)

    2003-08-01

    Purpose. - To identify prognostic factors and treatment toxicity in a series of epidermoid cancers of the anal canal without evident metastasis. Patients and methods. - Between June 1972 and January 1997, 305 patients (pts) were treated with curative-intent radiation therapy (RT). The T-stages according to the 1987 UICC classification were: 26 T1, 141 T2, 104 T3, and 34 T4. There were 49 pts with nodal involvement at presentation. Pretreatment anal function scoring according to our in-house system was: 22 scored 0, 182 scored 1, 74 scored 2, 7 scored 3. 11 scored 4, and 9 not available pts. The treatment started with external beam RT (EBRT) in 303 pts (median dose: 45 Gy). After a rest period of 4 to 6 weeks, a boost of 20 Gy was delivered by EBRT in 279 pts and by interstitial {sup 192}Ir brachytherapy (Bcy) in 17 pts. Seven pts received only one course of EBRT (mean dose: 49.5 Gy) and 2 pts were treated with interstitial {sup 192}Ir Bcy alone (55 and 60 Gy, respectively). concomitant chemotherapy (5-fluoro-uracil and either mitomycin C or cisplatin) was delivered to 19 pts. Mean follow-up was 103 months. Results. - At the end of RT local tumor clinical complete response (cCR) rate was 80%. Out of 61 non responders or local progressive tumors 27 (44%) were salvaged with abdomino-perineal resection (APR). The rate of local tumor relapse (LR) was 12%. Out of 37 LTR, 20 (54%) were salvaged with APR and one with interstitial {sup 192}Ir Bcy. The overall local tumor control (LC) rate with or without salvage local treatment was 84%. LC rate with a good anal function scoring (score 0 and 1) was 56.5%0. Among 181/186 available pts who preserved their anus, 94% had a good anal function scoring. For a subgroup of 15 pts with length tumor <2 cm-N0, the LC rate after the end of RT was 100% the LC rate with or without local salvage treatment was 100%, and among 13 available pts who preserved their anus, the anal function scoring was good in 12 pts (92%). The 10-years disease

  8. Combined radiotherapy and chemotherapy with cyclophosphamide, adriamycin, methotrexate, procarbazine (camp) in 64 consecutive patients with epidermoid bronchogenic carcinoma, limited disease: a prospective study

    International Nuclear Information System (INIS)

    Sixty-four consecutive patients with inoperable epidermoid bronchogenic carcinoma (limited disease) were treated with radiotherapy to the primary and nodal areas and combination chemotherapy with cyclophosphamide, adriamycin, methotrexate and procarbazine. The overall response rate (CR + PR) to combined treatment was 62%. The median survival time was 12.7 months. The toxicity was acceptable and no treatment-related death occurred

  9. ALA-PpIX variability quantitatively imaged in A431 epidermoid tumors using in vivo ultrasound fluorescence tomography and ex vivo assay

    Science.gov (United States)

    DSouza, Alisha V.; Flynn, Brendan P.; Gunn, Jason R.; Samkoe, Kimberley S.; Anand, Sanjay; Maytin, Edward V.; Hasan, Tayyaba; Pogue, Brian W.

    2014-03-01

    Treatment monitoring of Aminolevunilic-acid (ALA) - Photodynamic Therapy (PDT) of basal-cell carcinoma (BCC) calls for superficial and subsurface imaging techniques. While superficial imagers exist for this purpose, their ability to assess PpIX levels in thick lesions is poor; additionally few treatment centers have the capability to measure ALA-induced PpIX production. An area of active research is to improve treatments to deeper and nodular BCCs, because treatment is least effective in these. The goal of this work was to understand the logistics and technical capabilities to quantify PpIX at depths over 1mm, using a novel hybrid ultrasound-guided, fiber-based fluorescence molecular spectroscopictomography system. This system utilizes a 633nm excitation laser and detection using filtered spectrometers. Source and detection fibers are collinear so that their imaging plane matches that of ultrasound transducer. Validation with phantoms and tumor-simulating fluorescent inclusions in mice showed sensitivity to fluorophore concentrations as low as 0.025μg/ml at 4mm depth from surface, as presented in previous years. Image-guided quantification of ALA-induced PpIX production was completed in subcutaneous xenograft epidermoid cancer tumor model A431 in nude mice. A total of 32 animals were imaged in-vivo, using several time points, including pre-ALA, 4-hours post-ALA, and 24-hours post-ALA administration. On average, PpIX production in tumors increased by over 10-fold, 4-hours post-ALA. Statistical analysis of PpIX fluorescence showed significant difference among all groups; pvalidated by exvivo imaging of resected tumors. Details of imaging, analysis and results will be presented to illustrate variability and the potential for imaging these values at depth.

  10. Retrospective study of the global survival and local control after post-operative radiotherapy of head and neck epidermoid cancers; etude retrospective de la survie globale et du controle local apres radiotherapie postoperatoire des cancers epidermoides de la tete et du cou

    Energy Technology Data Exchange (ETDEWEB)

    Tanguy, R.; Taste, H.; Mecellem, H.; Graff, P.; Peiffert, D. [Centre Alexis-Vautrin, Nancy (France)

    2011-10-15

    The authors report the analysis of determining factors of global survival and of survival without recurrence within a cohort of 166 patients treated by post-operative irradiation for an epidermoid carcinoma of the upper aero-digestive tract. The analysis reveals the impact of capsular effraction on global survival and justifies a radiotherapy boost and a concomitant chemotherapy. Short communication

  11. Combinatorial effects of geopropolis produced by Melipona fasciculata Smith with anticancer drugs against human laryngeal epidermoid carcinoma (HEp-2) cells.

    Science.gov (United States)

    Bartolomeu, Ariane Rocha; Frión-Herrera, Yahima; da Silva, Livia Matsumoto; Romagnoli, Graziela Gorete; de Oliveira, Deilson Elgui; Sforcin, José Maurício

    2016-07-01

    The identification of natural products exerting a combined effect with therapeutic agents could be an alternative for cancer treatment, reducing the concentration of the drugs and side effects. Geopropolis (Geo) is produced by some stingless bees from a mixture of vegetable resins, gland secretions of the bees and soil. It has been used popularly as an antiseptic agent and to treat respiratory diseases and dermatosis. To determine whether Geo enhances the anticancer effect of carboplatin, methotrexate and doxorubicin (DOX), human laryngeal epidermoid carcinoma (HEp-2) cells were treated with Geo alone or in combination with each drug. Cell growth, cytotoxicity and apoptosis were evaluated using 3-(4,5-dimethyl thiazol-2yl)-2,5-diphenyltetrazolium bromide (MTT) assay, lactate dehydrogenase (LDH) release, and flow cytometry. Scratch assay was used to analyze cell migration and transmission electron microscopy to observe morphologic alterations. The influence of Geo on drug resistance was also investigated assessing P-glycoprotein (P-gp) action. Geo inhibited cell proliferation and migration. The combination Geo+DOX led to the highest cytotoxic activity and induced apoptosis, leading to loss of membrane integrity. Geo had no effect on P-gp-mediated efflux of DOX. Data indicate that Geo combined with DOX could be a potential clinical chemotherapeutic approach for laryngeal cancer treatment. PMID:27261576

  12. Carcinoma of Maxillary Sinus. A case Presentation.

    Directory of Open Access Journals (Sweden)

    Blas Jorge González Manso

    2007-08-01

    Full Text Available Tumors of the nasosinuous tract developed in the air cavities usually present a considerable growing before the patient feel any symptom or sign. Great part of the symptomatology is given due to the invasion of the tumor to neighbour structures such as oral and nasal cavities and orbits. A case of a 62 year-old male patient is presented after being under a dental extraction. A bucco-sinuous communication was diagnosed. It did not respond to different treatments and after some moths an epidermoid carcinoma of the right maxillary sinus appeared. It is of great interest to let this case been known in order to outstand the importance of an early diagnosis to get a better vital prognosis in this kinds of lesions.

  13. Malformação da transição crânio-vertebral como causa de síndrome do ângulo ponto-cerebelar: relato de dois casos Cerebello-pontine angle syndrome associated with cranio-vertebral malformation: report of two cases

    Directory of Open Access Journals (Sweden)

    Amauri Batista da Silva

    1972-03-01

    Full Text Available Os autores relatam dois casos de síndrome do ângulo ponto-cerebelar nos quais não havia neoplasia nessa região. Ambos os pacientes apresentavam uma associação de impressão basilar com síndrome de Arnold-Chiari. Após cirurgia descompressiva de fossa posterior os casos evoluiram favoravelmente com a diminuição progressiva dos sintomas neurológicos, restando apenas, no segundo paciente, certo grau de paralisia e de espasmo facial, à direita. São feitas considerações em tôrno das causas mais freqüentes da síndrome do ângulo ponto-cerebelar, bem como acêrca dos quadros clínicos mais usualmente encontrados em doentes que apresentam malformações da transição crânio-vertebral. Finalmente, os autores tecem breves considerações a respeito do possível mecanismo lesionai do VIII, do V e do VII nervos cranianos nos dois casos relatados.Two cases of cerebelo-pontine angle syndrome associated with basilar impression and Arnold-Chiari malformation are reported. In both cases neuroradiological studies and surgical exploration failled to demonstrate any space occupying lesion. After surgery the patients progressively recovered disapearing the neurological symptoms except for a slaight hemifacial spasm that remained in case 2. Clinical signs present in cerebello-pontine angle lesions and the occipito-cervical malformations are discussed. A possible mechanism to explain the association of both conditions is discussed.

  14. Subtotal resection and omentoplasty of the epidermoid splenic cyst: a case report

    OpenAIRE

    Krasniqi, Avdyl S.; Spahija, Gazmend S; Hashani, Shemsedin I; Osmani, Eshref A; Hoxha, Sejdullah A; Hamza, Astrit H; Gashi-Luci, Lumturije H

    2009-01-01

    Introduction Nonparasitic splenic cysts are uncommon clinical entity and because of it, there is no information regarding their optimal surgical treatment. Case presentation A 41-years-old female with incidentally diagnosed nonparasitic splenic cyst which initially was asymptomatic. After two years of follow up, the patient underwent surgery; subtotal cystectomy and omentoplasty as an additional procedure. Postoperative course was uneventful. Conclusion Short and mid term results showed that ...

  15. [Incidence of epidermoid cancer of the esophagus in Asturias (1975-85)].

    Science.gov (United States)

    Prados, C; Rodrigo Sáez, L; Fernández García, J; Fernández León, A; De Llano Rodríguez, I

    1990-06-01

    We present the incidence the esophageal squamous cell carcinoma in Asturias, based on the review of the clinical histories of eleven years (1975-85). Of 356 total cases, 92.4% were male patients and the remaining 7.6% females; the relation M:F was 12.2:1. Mean age at the time of diagnosis was 59.4 +/- 9.6 for males and 70 +/- for females. Total annual incidence was 2.8 +/- 0.8 cases/10(5) + population/year. Maximal annual incidence was registered in 1981: 1.1 cases/10(5) population/year. Asturias has eight health districts; those with highest incidence were mining areas: Mieres, Cangas de Narcea and Riaño. Compared to that of some developing countries, the incidence of esophageal cancer in Asturias is low, similar to that in European countries (except France) and white population of the USA; there is an aggregation of cases in males living in mining areas. PMID:2223247

  16. Evaluation of epidermal growth factor interaction with cell surface and its accumulation in nuclei of lung carcinoma, epidermoid carcinoma and melanoma cell lines

    International Nuclear Information System (INIS)

    Specificity of binding to cell surface and nuclear accumulation of labelled epidermal growth factor (EGF) was investigated in lung carcinoma (A549), epidermoid carcinoma (HEp-2) and melanoma (B16) cell lines. It was demonstrated that the labelled EGF was bound specifically to the cell surface in line A549, HEp-2 and B16 cells; the latter exhibiting the lowest binding capacity and highest binding affinity. Comparison of nuclear accumulation of the labelled growth factor in these cell lines indicated, that melanoma cell line specifically accumulated the 125I-EGF in nuclei whereas A549 and HEp-2 did not. Thus, in order to evaluate the effect of EGF in various cells, a strict control of binding affinity and background binding is required. (author). 19 refs, 3 figs, 1 tab

  17. Penis epidermoidal carcinoma

    International Nuclear Information System (INIS)

    It deals with a 58-years-old male, white man, with antecedents of blood hypertension, and increasing lesions in the penis since around 20 years ago, with changing locations. Two years ago it was diagnosed as acuminated condylomas, but it was not treated. The patient attended our hospital because twenty days ago the lesions adopted a tumor like aspect, and began to get abscessed, to ulcerate. The case was evaluated together with Dermatology and Urology. After some antibiotic treatments, it was obtained a biopsy of the lesion. The case is interesting because of the uncommon localization of the lesions in our patient and the increased level of the disease

  18. The place of radiotherapy in muco-epidermoid carcinomas of salivary glands in child; Place de la radiotherapie dans les carcinomes mucoepidermoides des glandes salivaires de l'enfant

    Energy Technology Data Exchange (ETDEWEB)

    Thariat, J. [Centre Antoine-Lacassagne, Nice (France); Temam, S. [Institut Gustave-Roussy, Villejuif (France); Orbach, D. [Institut Curie, Paris (France); Nicollas, R.; Penicaud, M. [Hopital La Timone, Marseille (France); Toussaint, B. [CHU, Nancy (France); Makeieff, M. [CHU, Montpellier (France); Laprie, A. [Institut Claudius-Regaud, Toulouse (France); Castillo, L. [CHU, Nice (France); Vedrin, P. [CHC de Cannes, Cannes (France)

    2011-10-15

    As muco-epidermoid carcinomas are the most frequent tumours of salivary glands for child, the authors report the study of the role of radiotherapy. This study is based on a survey performed in 34 paediatric departments. The authors analyse the age and gender, the use of irradiation, the tumour location, the tumour grade and size, the use of surgery and of radiotherapy, and survival. Radiotherapy is beneficial for high grade tumours, but cannot be recommended for low and intermediate grades. Short communication

  19. Carcinoma epidermoide do pênis: estudo clínico-patológico de 34 casos Squamous cell carcinoma of the penis: clinicopathologic study of 34 cases

    Directory of Open Access Journals (Sweden)

    Fabiana Braga França Wanick

    2011-12-01

    Full Text Available FUNDAMENTOS: No Brasil, a incidência do câncer do pênis é de 8,3 casos/100.000 habitantes, contrastando com 0,7 na Europa e nos Estados Unidos. Em 95% dos casos, trata-se do carcinoma epidermoide. Em geral, é diagnosticado tardiamente. OBJETIVOS: Descrever as características clínico-patológicas do carcinoma epidermoide do pênis, registradas no Hospital entre 1978 e 2004. MÉTODOS: Estudo observacional transversal. Incluíram-se os casos de carcinoma epidermoide do pênis, confirmados histologicamente. Avaliaram-se, pessoalmente, os pacientes que atenderam à convocação para o estudo, enquanto os demais tiveram seus dados pesquisados nos prontuários médicos. RESULTADOS: Registraram-se 34 pacientes com carcinoma epidermoide do pênis: 8 in situ e 26 invasivos, com idade média de 54,7 12,5 anos, respectivamente. A± 22,4 e 64,7 ±, a glande foi acometida em 91,1% dos casos e o prepúcio, em 41,1%. Os carcinomas epidermoides in situ exibiam pápulas ou eritema e erosão, geralmente menores do que 2 cm. Os invasivos mostravam úlceras e/ou vegetações, geralmente únicas, e maiores do que 2 cm. Dos CE invasivos, 80,8% eram bem diferenciados; metade encontrava-se no estágio I TNM e o restante, do II ao IV; 16 pacientes tiveram o pênis amputado e 3 faleceram. CONCLUSÕES: O câncer do pênis é raro, acomete adultos de todas as faixas etárias e o tratamento pode ser agressivo. O aspecto clínico inespecífico das lesões iniciais, o insuficiente treinamento médico em lesões dermatológicas e a carência de rotinas de investigação diagnóstica, tratamento e acompanhamento destes casos contribuem para o mau prognóstico desta neoplasia.BACKGROUND: In Brazil, the incidence of penile cancer is 8.3 cases per 100,000 population, in contrast to 0.7 in Europe and the United States. 95% of these cases correspond to squamous cell carcinoma (SCC. It is usually diagnosed late. OBJECTIVES: To describe the clinicopathologic features of squamous

  20. Carcinoma epidermoide como complicação letal de lesões crônicas de cromoblastomicose Chromoblastomycosis associated with a lethal squamous cell carcinoma

    Directory of Open Access Journals (Sweden)

    Edoardo Torres

    2010-04-01

    Full Text Available A cromoblastomicose é uma micose subcutânea, ocasionada por fungos dermatófitos, dos gêneros: Fonsecaea, Phialophora e Cladophialophora. As complicações habituais são: infecções secundárias, linfedema e elefantíase. Em lesões crônicas, tem-se documentado malignização. Relatamos um caso de um homem de 72 anos de idade, com cromoblastomicose de 30 anos de evolução, em região glútea, com desenvolvimento de carcinoma epidermoide.Chromoblastomycosis is a subcutaneous mycosis caused by the dermatophytic fungi Fonsecaea, Phialophora and Cladophialophora. Usual complications include secondary infection, lymphedema and elephantiasis. Associated malignancies have been found in chronic cases. This case report describes a 72 year-old male with a 30 year history of chromoblastomycosis in the gluteal region, who went on to develop a squamous cell carcinoma.

  1. Enediyne lidamycin enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitor, gefitinib, in epidermoid carcinoma A431 cells and lung carcinoma H460 cells.

    Science.gov (United States)

    Liu, Hong; Li, Liang; Li, Xing-Qi; Liu, Xiu-Jun; Zhen, Yong-Su

    2009-01-01

    Gefitinib, a low-molecular-weight epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, is effective in a wide variety of tumor types. Preclinical studies have shown potentiated antitumor efficacies of this agent in combination with chemotherapy or radiotherapy. The antitumor antibiotic lidamycin (LDM) showed extremely potent cytotoxicity in vitro and marked therapeutic effect in vivo. In this report, the cytotoxic and biochemical activity of LDM and gefitinib on human epidermoid carcinoma A431 cells and human large cell lung cancer H460 cells as a single agent or in combination has been evaluated. In the MTT assay, LDM showed much more potent cytotoxicity than gefitinib to both cell lines. A431 cells with a highly EGFR-expressing level were more sensitive to gefitinib than H460 cells, which expressed EGFR at an intermediate level. LDM plus gefitinib showed potentiation of antiproliferative activity and apoptosis induction, which were associated with downregulation of EGFR signaling pathway and nuclear factor-kappa B expression, and the increase of cleaved poly (adenosine diphosphate-ribose) polymerase in the two cell lines, although to a lesser degree in H460 cells. Combined treatment induced G1 phase arrest similar to that of gefitinib alone in A431 cells and intensified G2/M phase accumulation in H460 cells. The above results indicate that LDM potentiates the effects of gefitinib in both gefitinib sensitive and less sensitive cells in association with enhanced inhibition of EGFR-dependent signaling. PMID:19342999

  2. Resveratrol enhances ultraviolet B-induced cell death through nuclear factor-κB pathway in human epidermoid carcinoma A431 cells

    International Nuclear Information System (INIS)

    Resveratrol has been reported to suppress cancer progression in several in vivo and in vitro models, whereas ultraviolet B (UVB), a major risk for skin cancer, is known to induce cell death in cancerous cells. Here, we investigated whether resveratrol can sensitize A431 human epidermoid carcinoma cells to UVB-induced cell death. We examined the combined effect of UVB (30 mJ/cm2) and resveratrol (60 μM) on A431 cells. Exposure of A431 carcinoma cells to UVB radiation or resveratrol can inhibit cell proliferation and induce apoptosis. However, the combination of resveratrol and UVB exposure was associated with increased proliferation inhibition of A431 cells compared with either agent alone. Furthermore, results showed that resveratrol and UVB treatment of A431 cells disrupted the nuclear factor-kappaB (NF-κB) pathway by blocking phosphorylation of serine 536 and inactivating NF-κB and subsequent degradation of IκBα, which regulates the expression of survivin. Resveratrol and UVB treatment also decreased the phosphorylation of tyrosine 701 of the important transcription factor signal transducer activator of transcription (STAT1), which in turn inhibited translocation of phospho-STAT1 to the nucleus. Moreover, resveratrol/UVB also inhibited the metastatic protein LIMK1, which reduced the motility of A431 cells. In conclusion, our study demonstrates that the combination of resveratrol and UVB act synergistically against skin cancer cells. Thus, resveratrol is a potential chemotherapeutic agent against skin carcinogenesis.

  3. Artesunate induces G0/G1 cell cycle arrest and iron-mediated mitochondrial apoptosis in A431 human epidermoid carcinoma cells.

    Science.gov (United States)

    Jiang, Zhongyong; Chai, Jin; Chuang, Henry Hon Fung; Li, Shifeng; Wang, Tianran; Cheng, Yi; Chen, Wensheng; Zhou, Deshan

    2012-07-01

    The anticancer effects of artesunate (ART) have been well documented. However, its potential against skin cancer has not been explored yet. Herein we reported that 60 μmol/l ART effectively inhibited A431 (human epidermoid carcinoma cells) growth but not that of HaCaT (normal human keratinocyte cells). Our results revealed that ART induced cell cycle arrest at G0/G1 phase through the downregulation of cyclin A1, cyclin B, cyclin D1, Cdk2, Cdk4, and Cdk6. This correlated with the upregulation of p21 and p27. The 5-bromodeoxyuridine incorporation assay also indicated that ART treatment reduced DNA synthesis in a time-dependent manner. Furthermore, ART induced mitochondrial apoptosis, as evidenced by annexin V/propidium iodide staining and western blot analysis. Interestingly, ART-induced apoptosis diminished under iron-deficient conditions but intensified under iron-overload conditions. Taken together, these findings demonstrated the potential of ART in treating skin cancer through the induction of G0/G1 cell cycle arrest and iron-mediated mitochondrial apoptosis and supported further investigations in other test systems. PMID:22421370

  4. JNK signaling maintains the mesenchymal properties of multi-drug resistant human epidermoid carcinoma KB cells through snail and twist1

    International Nuclear Information System (INIS)

    In addition to possess cross drug resistance characteristic, emerging evidences have shown that multiple-drug resistance (MDR) cancer cells exhibit aberrant metastatic capacity when compared to parental cells. In this study, we explored the contribution of c-Jun N-terminal kinases (JNK) signaling to the mesenchymal phenotypes and the aberrant motile capacity of MDR cells utilizing a well characterized MDR cell line KB/VCR, which is established from KB human epidermoid carcinoma cells by vincristine (VCR), and its parental cell line KB. Taking advantage of experimental strategies including pharmacological tool and gene knockdown, we showed here that interference with JNK signaling pathway by targeting JNK1/2 or c-Jun reversed the mesenchymal properties of KB/VCR cells to epithelial phenotypes and suppressed the motile capacity of KB/VCR cells, such as migration and invasion. These observations support a critical role of JNK signaling in maintaining the mesenchymal properties of KB/VCR cells. Furthermore, we observed that JNK signaling may control the expression of both snail and twist1 in KB/VCR cells, indicating that both snail and twist1 are involved in controlling the mesenchymal characteristics of KB/VCR cells by JNK signaling. JNK signaling is required for maintaining the mesenchymal phenotype of KB/VCR cells; and JNK signaling may maintain the mesenchymal characteristics of KB/VCR cells potentially through snail and twist1

  5. [5 cases of epidermoid cyst (or primary cholesteatoma) of the petrous pyramid. Clinical, radiologic, pathogenic and therapeutic aspects. Value of nuclear magnetic resonance in the diagnosis and postoperative monitoring].

    Science.gov (United States)

    Tran Ba Huy, P; Lévy, C; Bensimon, J L; Cophignon, J

    1986-01-01

    Five cases of epidermoid cyst (or primary cholesteatoma) of petrous bone are described and the criteria necessary to consider these tumors as truly primary outlined. The most plausible theories appear to be either congenital: embryonic inclusions or, to a lesser degree, acquired: papillary proliferation. Emphasis is placed on facial signs, even minimal, associated with progressive perception or mixed unilateral deafness. Advantages and indications for different surgical approaches are discussed and the value of NMR imaging emphasized, both for diagnosis and postoperative follow up review, especially when a closed technique had been selected. PMID:3789583

  6. Carcinoma epidermoide cutáneo: relación con los trastornos respiratorios del sueño y definición de la variante alto riesgo

    OpenAIRE

    Díaz Corpas, Tania

    2015-01-01

    Introducción: Recientes publicaciones han mostrado que la hipoxia intermitente similar a la que encontramos en el síndrome de apnea e hipopnea del sueño (SAHS) parece estar implicada en el desarrollo, progresión y crecimiento de tumores en modelos animales, a través de la sobreproducción de factores de crecimiento (entre ellos el factor de crecimiento vascular endotelial o VEGF) y la interacción con la vía supresora del gen p53. EL carcinoma epidermoide cutáneo (CEC) es un tumor procede...

  7. La técnica de exploración con Imagen de Banda Estrecha o Narrow Band Imaging (NBI) en carcinomas epidermoides de la vía aerodigestiva superior

    OpenAIRE

    Barberá Durbán, Rafael

    2014-01-01

    INTRODUCCIÓN: La mayoría de las neoplasias malignas de cabeza y cuello son carcinomas epidermoides originados en la vía aerodigestiva superior. Debido a su localización preferente en la superficie de la mucosa, la exploración endoscópica en la consulta es fundamental. Para mejorar la exploración visual endoscópica de las lesiones y tratar de aislarlas de la mucosa sana se ha desarrollado la técnica de exploración con luz de banda estrecha (Narrow Band Imaging o NBI). Inicialmente utilizada pa...

  8. Estudio clínico y aplicación diagnóstica y pronóstica de los biomarcadores proteómicos salivares en el cáncer epidermoide faringolaríngeo

    OpenAIRE

    Pelegrín Hernández, Juan Pablo

    2015-01-01

    El Cáncer Epidermoide de Cabeza y Cuello (CECC) es una entidad neoplásica maligna que se origina en el epitelio que recubre la mucosa de la vía areodigestiva. Frecuentemente se diagnostica en etapas avanzadas de la enfermedad, lo que le confiere un pronóstico sombrío. En la actualidad resulta paradójico que, con los medios disponibles, no tenemos programas eficaces para la detección precoz de este tipo de tumores. Con esta Tesis nos proponemos, como objetivo general, analizar la capacida...

  9. Profundidad tumoral y variables histopatológicas en el carcinoma epidermoide lingual: Estudio retrospectivo sobre 60 pacientes Tumoral thickness and histopathological parameters in the squamous cell carcinoma of tongue: A retrospective evaluation over 60 patients

    OpenAIRE

    JD Sánchez López; MA Sicilia Gutiérrez; LM Capitán Cañadas; I. Labrot Moleón; S. Martínez-Villalobos Castillo; E. Valencia Laseca

    2005-01-01

    I.- Introducción: La profundidad tumoral representa uno de los principales factores pronósticos del carcinoma epidermoide lingual. II.-Objetivos: Verificar si el espesor máximo tumoral se correlaciona con parámetros histopatológicos agresivos. III.-Material y Métodos: -Diseño: Estudio retrospectivo de base hospitalaria (Enero-1990 a Julio-1997) constituido por 60 pacientes afectos de carcinoma escamoso lingual. -Variables: Filiación del paciente, parámetros histopatológicos y profundidad tumo...

  10. Vorinostat, an HDAC inhibitor attenuates epidermoid squamous cell carcinoma growth by dampening mTOR signaling pathway in a human xenograft murine model

    International Nuclear Information System (INIS)

    Histone deacetylase (HDAC) inhibitors are potent anticancer agents and show efficacy against various human neoplasms. Vorinostat is a potent HDAC inhibitor and has shown potential to inhibit growth of human xenograft tumors. However, its effect on the growth of skin neoplasm remains undefined. In this study, we show that vorinostat (2 μM) reduced expression of HDAC1, 2, 3, and 7 in epidermoid carcinoma A431 cells. Consistently, it increased acetylation of histone H3 and p53. Vorinostat (100 mg/kg body weight, IP) treatment reduced human xenograft tumor growth in highly immunosuppressed nu/nu mice. Histologically, the vorinostat-treated tumor showed features of well-differentiation with large necrotic areas. Based on proliferating cell nuclear antigen (PCNA) staining and expression of cyclins D1, D2, E, and A, vorinostat seems to impair proliferation by down-regulating the expression of these proteins. However, it also induced apoptosis. The mechanism by which vorinostat blocks proliferation and makes tumor cells prone to apoptosis, involved inhibition of mTOR signaling which was accompanied by reduction in cell survival AKT and extracellular-signal regulated kinase (ERK) signaling pathways. Our data provide a novel mechanism-based therapeutic intervention for cutaneous squamous cell carcinoma (SCC). Vorinostat may be utilized to cure skin neoplasms in organ transplant recipient (OTR). These patients have high morbidity and surgical removal of these lesions which frequently develop in these patients, is difficult. -- Highlights: ► Vorinostat reduces SCC growth in a xenograft murine model. ► Vorinostat dampens proliferation and induces apoptosis in tumor cells. ► Diminution in mTOR, Akt and ERK signaling underlies inhibition in proliferation. ► Vorinostat by inhibiting HDACs inhibits epithelial–mesenchymal transition.

  11. Silibinin modulates UVB-induced apoptosis via mitochondrial proteins, caspases activation, and mitogen-activated protein kinase signaling in human epidermoid carcinoma A431 cells

    International Nuclear Information System (INIS)

    Several recent studies by us have shown the strong chemopreventive efficacy of silibinin against both ultraviolet B (UVB) radiation and chemical carcinogen-induced tumorigenesis in mouse skin models. The molecular mechanisms underlying silibinin protective efficacy, however, are not completely known. Here, we examined the effect of silibinin on UVB-caused apoptosis in human epidermoid carcinoma A431 cells. Irradiation of cells with different doses of UVB (5-100 mJ/cm2) and different time periods (0.5-24 h) resulted in a dose- and time-dependent increase in apoptosis (P<0.05-0.001). Silibinin (100-200 μM) pre-treatment, however, resulted in an increase in UVB-induced apoptosis (P<0.05-0.001); interestingly, its post-treatment caused a decrease in UVB-induced apoptosis (P<0.05-0.001). A similar pattern in the activation of caspases-9, -3, and -7 was observed with these silibinin treatments. Further, silibinin treatment prior to or immediately after UVB exposure altered Bcl-2, Bax, Bak, and cytochrome c levels in mitochondria and cytosol in favor of or against apoptosis, respectively. Silibinin treatment prior to UVB also increased the activation of mitogen/stress activated protein kinases Erk1/2, JNK, and p38 kinase as compared to its post-treatment. Together, for the first time, our results demonstrate the role of mitochondrial apoptotic machinery and MAPK signaling cascade in silibinin-caused increase as well as protection in UVB-induced apoptosis in A431 cells, and suggest that similar mechanisms might be involved in preventive efficacy of silibinin against UVB-induced skin tumorigenesis

  12. Profundidad tumoral en el carcinoma epidermoide lingual: Repercusiones diagnósticas Tumor depth in squamous cell carcinoma of the tongue: Diagnostic repercussions

    Directory of Open Access Journals (Sweden)

    J.D. Sánchez López

    2007-02-01

    Full Text Available Objetivo. Determinar el grado de concordancia entre la valoración clínica (cT e histopatológica (pT del tamaño del carcinoma epidermoide lingual en relación a la introducción del parámetro de profundidad tumoral (ppT. Material y métodos. 1 Diseño: Estudio retrospectivo de base hospitalaria constituido por 60 pacientes evaluados desde Enero de 1990 a Julio de 1997 (Seguimiento mínimo de 8 años. 2 Variables: Filiación del paciente, parámetros clínicos y parámetros histopatológicos. 3 Método estadístico: Correlación mediante el Indice Kappa (pObjective. To determine the degree of concordance between clinical (cT and histopathological (pT values for tumor size in squamous cell carcinoma when introducing "tumor thickness" as a diagnostic marker. Materials and methods. 1 Design: A retrospective hospital study of 60 patients evaluated between January 1990 and July 1997 was carried out. 2 Variables: Patient dates, clinical and histopathological parameters. 3 Statistics: Correlation assessment by Kappa Index (p<0.05. Results. After the use of "tumor thickness" as a diagnostic indicator the following can be appreciated: • Correlation between cT and ppT: Reduction in the degree of concordance between cT and pT in relation to ppT (23.3 /12.5%. • Correlation between pT and ppT: 100% concordance between pT4 and ppT4. All tumors diagnosed as pT3 were changed to ppT4. Conclusion. When the parameter "tumor thickness" is used, a change can be appreciated in the early stage clinical and histopathological diagnosis, as tumor size (T becomes advanced.

  13. Vorinostat, an HDAC inhibitor attenuates epidermoid squamous cell carcinoma growth by dampening mTOR signaling pathway in a human xenograft murine model

    Energy Technology Data Exchange (ETDEWEB)

    Kurundkar, Deepali; Srivastava, Ritesh K.; Chaudhary, Sandeep C. [Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019 (United States); Ballestas, Mary E. [Department of Pediatrics Infectious Disease, Children' s of Alabama, School of Medicine, University of Alabama at Birmingham, AL (United States); Kopelovich, Levy [Division of Cancer Prevention, National Cancer Institute, 6130 Executive Blvd., Suite 2114, Bethesda, MD 20892 (United States); Elmets, Craig A. [Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019 (United States); Athar, Mohammad, E-mail: mathar@uab.edu [Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019 (United States)

    2013-01-15

    Histone deacetylase (HDAC) inhibitors are potent anticancer agents and show efficacy against various human neoplasms. Vorinostat is a potent HDAC inhibitor and has shown potential to inhibit growth of human xenograft tumors. However, its effect on the growth of skin neoplasm remains undefined. In this study, we show that vorinostat (2 μM) reduced expression of HDAC1, 2, 3, and 7 in epidermoid carcinoma A431 cells. Consistently, it increased acetylation of histone H3 and p53. Vorinostat (100 mg/kg body weight, IP) treatment reduced human xenograft tumor growth in highly immunosuppressed nu/nu mice. Histologically, the vorinostat-treated tumor showed features of well-differentiation with large necrotic areas. Based on proliferating cell nuclear antigen (PCNA) staining and expression of cyclins D1, D2, E, and A, vorinostat seems to impair proliferation by down-regulating the expression of these proteins. However, it also induced apoptosis. The mechanism by which vorinostat blocks proliferation and makes tumor cells prone to apoptosis, involved inhibition of mTOR signaling which was accompanied by reduction in cell survival AKT and extracellular-signal regulated kinase (ERK) signaling pathways. Our data provide a novel mechanism-based therapeutic intervention for cutaneous squamous cell carcinoma (SCC). Vorinostat may be utilized to cure skin neoplasms in organ transplant recipient (OTR). These patients have high morbidity and surgical removal of these lesions which frequently develop in these patients, is difficult. -- Highlights: ► Vorinostat reduces SCC growth in a xenograft murine model. ► Vorinostat dampens proliferation and induces apoptosis in tumor cells. ► Diminution in mTOR, Akt and ERK signaling underlies inhibition in proliferation. ► Vorinostat by inhibiting HDACs inhibits epithelial–mesenchymal transition.

  14. MRI of the regions of inner ear and cerebellopontine angle using a 3D T2-weighted turbo spin-echo sequence. Comparison with conventional 2D T2-weighted turbo spin-echo sequences and T1-weighted spin-echo sequences

    International Nuclear Information System (INIS)

    Purpose: To assess the value of a three-dimensional (3D) T2-weighted turbo spin-echo sequence (3D T2-TSE) in comparison to conventional two-dimensional (2D) T2-weighted TSE and unenhanced and enhanced T1-weighted spin-echo sequences (SE) in imaging anatomic structures and pathologic changes of the inner ear and cerebellopontine angle. Patients and methods: The inner ear and cerebellopotine angle were investigated by MRI in three healthy volunteers and 18 patients performing a 2D T2-weighted turbo spin-echo sequence and a 3D T2-TSE in the axial plane. In the patient study, 2D T1-weighted SE sequences both before and after the i.v. injection of gadopentate dimeglumine in both the axial and coronal plane were performed in addition. Results: Only the 3D T2-TSE enabled an accurate imaging of the anatomic structures. In cases of pathology, the 3D T2-TSE provided additional information to the performed 2D sequences. The combination of the 3D T2-TSE with unenhanced and enhanced 2D T1-weighted SE enabled the most accurate diagnosis in case of pathology. Conclusions: Accurate depiction of anatomic structures of the inner ear and cerebellopontine angle could be obtained by 3D T2-TSE only. The most accurate diagnosis in cases of pathology was provided by the combination of the 3D T2-TSE with unenhanced and enhanced 2D T1-weighted spin-echo sequences. (orig.)

  15. Cerebellopontine angle pilocytic astrocytoma mimicking acoustic schwannoma

    Energy Technology Data Exchange (ETDEWEB)

    Takada, Y.; Ohno, K.; Tamaki, M.; Hirakawa, K. [Dept. of Neurosurgery, Tokyo Medical and Dental Univ. (Japan)

    1999-12-01

    We describe a case of pilocytic astrocytoma of the cerebellum mimicking an acoustic schwannoma. The tumour protruded into the porus acusticus and enlarged the internal auditory meatus, which is a quite unusual characteristic of glial tumours. (orig.)

  16. Cerebellopontine angle pilocytic astrocytoma mimicking acoustic schwannoma

    International Nuclear Information System (INIS)

    We describe a case of pilocytic astrocytoma of the cerebellum mimicking an acoustic schwannoma. The tumour protruded into the porus acusticus and enlarged the internal auditory meatus, which is a quite unusual characteristic of glial tumours. (orig.)

  17. Present time

    OpenAIRE

    Romero, Gustavo E.

    2014-01-01

    The idea of a moving present or `now' seems to form part of our most basic beliefs about reality. Such a present, however, is not reflected in any of our theories of the physical world. I show in this article that presentism, the doctrine that only what is present exists, is in conflict with modern relativistic cosmology and recent advances in neurosciences. I argue for a tenseless view of time, where what we call `the present' is just an emergent secondary quality arising from the interactio...

  18. Present time

    CERN Document Server

    Romero, Gustavo E

    2014-01-01

    The idea of a moving present or `now' seems to form part of our most basic beliefs about reality. Such a present, however, is not reflected in any of our theories of the physical world. I show in this article that presentism, the doctrine that only what is present exists, is in conflict with modern relativistic cosmology and recent advances in neurosciences. I argue for a tenseless view of time, where what we call `the present' is just an emergent secondary quality arising from the interaction of perceiving self-conscious individuals with their environment. I maintain that there is no flow of time, but just an ordered system of events.

  19. CATCHY PRESENTATIONS

    DEFF Research Database (Denmark)

    Eriksen, Kaare; Tollestrup, Christian; Ovesen, Nis

    2011-01-01

    and ideas in many areas and avoiding “Death by Powerpoint”. This paper discusses the need and tools for making short presentations and describes the result from a business development project where engineering graduate students in architecture and design used the Pecha Kucha format to present their...

  20. Grape seed proanthocyanidins promote apoptosis in human epidermoid carcinoma A431 cells through alterations in Cdki-Cdk-cyclin cascade, and caspase-3 activation via loss of mitochondrial membrane potential.

    Science.gov (United States)

    Meeran, Syed M; Katiyar, Santosh K

    2007-05-01

    Dietary grape seed proanthocyanidins (GSPs) prevent photocarcinogenesis in mice. Here, we report that in vitro treatment of human epidermoid carcinoma A431 cells with GSPs inhibited cellular proliferation (13-89%) and induced cell death (1-48%) in a dose (5-100 mug/ml)- and time (24, 48 and 72 h)-dependent manner. GSP-induced inhibition of cell proliferation was associated with an increase in G1-phase arrest at 24 h, which was mediated through the inhibition of cyclin-dependent kinases (Cdk) Cdk2, Cdk4, Cdk6 and cyclins D1, D2 and E and simultaneous increase in protein expression of cyclin-dependent kinase inhibitors (Cdki), Cip1/p21 and Kip1/p27, and enhanced binding of Cdki-Cdk. The treatment of A431 cells with GSPs (20-80 mug/ml) resulted in a dose-dependent increase in apoptotic cell death (26-58%), which was associated with an increased protein expression of proapoptotic Bax, decreased expression of antiapoptotic Bcl-2 and Bcl-xl, loss of mitochondrial membrane potential, and cleavage of caspase-9, caspase-3 and PARP. Pretreatment with the pan-caspase inhibitor (z-VAD-fmk) blocked the GSP-induced apoptosis in A431 cells suggesting that GSP-induced apoptosis is associated primarily with the caspase-3-dependent pathway. Together, our study suggests that GSPs possess chemotherapeutic potential against human epidermoid carcinoma cells in vitro, further in vivo mechanistic studies are required to verify the chemotherapeutic effect of GSPs in skin cancers. PMID:17437483

  1. Profundidad tumoral y variables histopatológicas en el carcinoma epidermoide lingual: Estudio retrospectivo sobre 60 pacientes Tumoral thickness and histopathological parameters in the squamous cell carcinoma of tongue: A retrospective evaluation over 60 patients

    Directory of Open Access Journals (Sweden)

    JD Sánchez López

    2005-10-01

    Full Text Available I.- Introducción: La profundidad tumoral representa uno de los principales factores pronósticos del carcinoma epidermoide lingual. II.-Objetivos: Verificar si el espesor máximo tumoral se correlaciona con parámetros histopatológicos agresivos. III.-Material y Métodos: -Diseño: Estudio retrospectivo de base hospitalaria (Enero-1990 a Julio-1997 constituido por 60 pacientes afectos de carcinoma escamoso lingual. -Variables: Filiación del paciente, parámetros histopatológicos y profundidad tumoral. -Procedimientos de laboratorio. -Métodos estadísticos: Estadística descriptiva e inferencial (Método Bonferroni, C- Dunnet, Chi-cuadrado y test de Anova. IV.-Resultados: Asociación estadísticamente significativa entre Indice mitótico y profundidad tumoral (14,84;pI.-Introduction: The tumoral thickness represents one of the most ominous prognostic factors of the squamous cell carcinoma of tongue. II.-Objectives: To verify if the tumoral thickness is relationated with others aggressive histopathologic parameters. III.-Material and Methods: -Design: A hospital population retrospective study (January-1990 to July-1997 of 60 patients affected of carcinoma of tongue. -Variables: Data patients, histopathological parameters and tumoral thickness. -Laboratory procedures. -Stadistic methods: Descriptive and Inferential stadistical: Bonferroni method, C-Dunnet, Chi-square, Anova test… IV.-Results: There is a statistic association between mitotic Index and tumoral thickness (14,84; p<0,001. V.-Conclusions: Depth of invasion and mitotic Index are actually associated prognostic factors in the carcinoma epidermoid of tongue.

  2. Lecture Presentations

    International Nuclear Information System (INIS)

    The Symposium on Physics of Elementary Interactions in the LHC Era held in Warsaw from 21 to 22 April 2008. The main subject of the workshop was to present the progress in CERN LHC collider project. Additionally some satellite activities in field of education, knowledge and technology transfer in the frame of CERN - Poland cooperation were shown

  3. Technical presentation

    CERN Multimedia

    FI Department

    2008-01-01

    RADIOSPARES, the leading catalogue distributor of components (electronic, electrical, automation, etc.) and industrial supplies will be at CERN on Friday 3 October 2008 (Main Building, Room B, from 9.00 a.m. to 3.00 p.m.) to introduce its new 2008/2009 catalogue. This will be the opportunity for us to present our complete range of products in more detail: 400 000 part numbers available on our web site (Radiospares France, RS International, extended range of components from other manufacturers); our new services: quotations, search for products not included in the catalogue, SBP products (Small Batch Production: packaging in quantities adapted to customers’ requirements); partnership with our focus manufacturers; demonstration of the on-line purchasing tool implemented on our web site in conjunction with CERN. RADIOSPARES will be accompanied by representatives of FLUKE and TYCO ELECTRONICS, who will make presentations, demonstrate materials and answer any technical questio...

  4. Technical presentation

    CERN Document Server

    FP Department

    2009-01-01

    07 April 2009 Technical presentation by Leuze Electronics: 14.00 – 15.00, Main Building, Room 61-1-017 (Room A) Photoelectric sensors, data identification and transmission systems, image processing systems. We at Leuze Electronics are "the sensor people": we have been specialising in optoelectronic sensors and safety technology for accident prevention for over 40 years. Our dedicated staff are all highly customer oriented. Customers of Leuze Electronics can always rely on one thing – on us! •\tFounded in 1963 •\t740 employees •\t115 MEUR turnover •\t20 subsidiaries •\t3 production facilities in southern Germany Product groups: •\tPhotoelectric sensors •\tIdentification and measurements •\tSafety devices

  5. Valoración de la expresión de Bcl2 y ki-67 en el carcinoma epidermoide de pulmón. Alteraciones génicas asociadas. Correlación con variables anatomoclínicas

    OpenAIRE

    Montejo Maillo, Beatriz

    2010-01-01

    [ES]Aparte del estudio clinico del tumor, escasos factores parecen influir en el pornóstico del carcinoma epidermoide de pulmón y en los úlitmos 20 años, apenas se ha modificado la supervivencia [EN]Apart from the clinical study of tumor, few factors appear to influence the porn squamous cell carcinoma of lung and in 20 years last article, has remained largely unchanged survival

  6. Carcinoma of Maxillary Sinus. A case Presentation. Carcinoma de seno maxilar. Presentación de caso.

    Directory of Open Access Journals (Sweden)

    Ángel Luis Cruz Leiva

    2007-01-01

    Full Text Available

    Tumors of the nasosinuous tract developed in the air cavities usually present a considerable growing before the patient feel any symptom or sign. Great part of the symptomatology is given due to the invasion of the tumor to neighbour structures such as oral and nasal cavities and orbits. A case of a 62 year-old male patient is presented after being under a dental extraction. A bucco-sinuous communication was diagnosed. It did not respond to different treatments and after some moths an epidermoid carcinoma of the right maxillary sinus appeared. It is of great interest to let this case been known in order to outstand the importance of an early diagnosis to get a better vital prognosis in this kinds of lesions.

    Los tumores del tracto nasosinusal al desarrollarse en cavidades aéreas, suelen presentar un considerable crecimiento antes de dar lugar a signos y síntomas. Gran parte de la sintomatología se debe a la invasión del tumor a estructuras vecinas, como son la órbita y la cavidad nasal y oral. Se presenta el caso de un paciente masculino, de 62 años de edad, al cual, tras haber sido sometido a una extracción dentaria, se le diagnosticó una comunicación bucosinusal, que no cedió a varias formas de tratamiento, lo que resultó varios meses después en un carcinoma epidermoide del seno maxilar derecho. El interés de dar a conocer este caso, radica en destacar la importancia de un diagnóstico precoz para conseguir mejorar el pronóstico vital en este tipo de afecciones.

  7. Tumor relapse present in oncologic nasal repair

    International Nuclear Information System (INIS)

    Introduction: Tumor relapse is one of the more fearsome complications of the oncologic course and also to obscure the life prognosis, causing the loss of many reconstructions and of exhausting the repairing surgical possibilities. The aim of this study was to determine the relapse frequency, the repercussion on the repair and the subsequent medical course of patients operated on malign nasal tumors. Methods: We made a retrospective and descriptive study in 20 patients operated on malign nasal tumors with immediate repair using frontal flap. Patients came from National Institute of Oncology and Radiobiology (NIOR), where they were seen from 2002 and 2007. Results: There were two relapses in 5 patients (25% of total), and the 80% of these were an epidermoid carcinoma. All patients with relapse lost the repaired tissues and received radiotherapy. Only it was possible to repair the defect in one of the patients; two of remained deceased, and were alive, without tumor relapse but without possibilities of repair. Conclusions: Considering the relapse frequency of nasal epidermoid carcinomas and of its repercussions when the Mhos histography technique is not available, it is advisable to delay the nasal repair until will be possible to confirm completely the histology of tumor exeresis. (author)

  8. La terapia fotodinámica y sus implicaciones en la prevención de queratosis actínicas y carcinoma epidermoide

    OpenAIRE

    Bagazgoitia Sáez de Vicuña, Lorea

    2010-01-01

    El presente trabajo, llevado a cabo en 22 pacientes con QAs, demuestra que: 1.El tratamiento con TFD tiene efectos celulares y moleculares que apoyan su efecto preventivo en QA ya que: a)Reduce la displasia queratinocítica basal y la elastosis solar, ambos indicadores de daño actínico crónico. b)Reduce la proliferación celular de la epidermis, reflejada por una disminución significativa de la expresión de ki-67 en todos los casos analizados. c)Reduce la expresión de p53, marcador precoz de on...

  9. Chemoradiotherapy in head and neck squamous cell carcinoma: focus on targeted therapies; La chimioradiotherapie des carcinomes epidermoides des voies aerodigestives superieures: point sur les therapeutiques ciblees

    Energy Technology Data Exchange (ETDEWEB)

    Bozec, A. [Centre Antoine-Lacassagne, Dept. de Chirurgie, Institut Universitaire de la Face et du Cou, 06 - Nice (France); Thariat, J.; Bensadoun, R.J. [Centre Antoine-Lacassagne, Dept. de Radiotherapie, Institut Universitaire de la Face et du Cou, 06 - Nice (France); Milano, G. [Centre Antoine-Lacassagne, Unite d' Oncopharmacologie, Institut Universitaire de la Face et du Cou, 06 - Nice (France)

    2008-01-15

    Radiotherapy is an essential treatment for many patients with head and neck squamous cell carcinoma. Its association with molecular targeted therapies represents a real progress. Among the recent advances in the molecular targeted therapy of cancer, the applications centred on E.G.F.R. are currently the most promising and the most advanced at clinical level. Considering the set of therapeutic tools targeting E.G.F.R., there are at present two well-identified emerging categories of drugs with monoclonal antibodies, on the one hand, and tyrosine kinase inhibitors, on the other. In many preclinical studies, the combination of anti-E.G.F.R. drugs with irradiation has led to additive or supra-additive cytotoxic effects. Furthermore, anti-angiogenic agents have shown promising results in association with anti-E.G.F.R. drugs and radiotherapy. This research effort has recently produced encouraging clinical results in advanced head and neck cancer with combination of cetuximab (an anti-E.G.F.R. monoclonal antibody) with irradiation with a significant impact on patient survival. Active and efficient clinical research is currently ongoing to determine the place of molecular targeted therapies in the treatment of head and neck cancer, particularly in association with radiotherapy. (authors)

  10. Virtual Presenters: Towards Interactive Virtual Presentations

    NARCIS (Netherlands)

    Nijholt, A.; Cappellini, V.; Hemsley, J.

    2005-01-01

    We discuss having virtual presenters in virtual environments that present information to visitors of these environments. Some current research is surveyed and we will look in particular to our research in the context of a virtual meeting room where a virtual presenter uses speech, gestures, pointing

  11. Making your presentation fun: creative presentation techniques

    Energy Technology Data Exchange (ETDEWEB)

    KEENEN,MARTHA JANE

    2000-05-18

    What possesses someone to volunteer and go through hoops and red tape to make a presentation at a conference? For that matter, why does anyone ever present anything to anyone? Actually, presentations are a fact of life and there are many reasons for doing a presentation and doing it well. New and existing staff need training and orientation to the way things are done here. Handing all of them a manual and hoping they read it is pretty much a waste of paper. On the other hand, an effective, entertaining and upbeat presentation on the relevant topics is more likely to stick with those people. They will even have a name and face to remember and seek out when they have an issue on or with that topic. This can be a very effective beginning for networking with new peers. The presenter is seen as knowledgeable, as a source of information on company topics and possibly evaluated as a potential mentor or future manager. Project staff and/or peers benefit from clear, concise, presentations of topical knowledge. This is one way that a group working on various aspects of the same project or program can stay in touch and in step with each other. Most importantly, presentations may be the best or only door into the minds (and budgets) of management and customers. These presentations are a wonderful opportunity to address legal and compliance issues, budget, staffing, and services. Here is a chance, maybe the only one, to demonstrate and explain the wonderfulness of a program and the benefit they get by using the services offered most effectively. An interactive presentation on legal and compliance issues can be an effective tool in helping customers and/or management make good risk management decisions.

  12. Lipoma in the Corpus Callosum Presenting with Epileptic Seizures Associated with Expanding Perifocal Edema: A Case Report and Literature Review

    Directory of Open Access Journals (Sweden)

    Michiyasu Fuga

    2015-01-01

    Full Text Available This report describes a rare case of a patient with lipoma presenting with epileptic seizures associated with expanding perifocal edema. The patient was a 48-year-old man who presented with loss of consciousness and convulsions. Magnetic resonance imaging (MRI revealed a calcified mass in the corpus callosum with perifocal edema causing mass effect. An interhemispheric approach was used to biopsy the mass lesion. Histological examination revealed typical adipose cells, along with hamartomatous components. These components contained neurofilament and S-100-positive structures showing marked calcification. Fibrous cells immunoreactive for α-smooth muscle actin and epithelial membrane antigen proliferated with focal granulomatous inflammatory changes. MIB-1 index was approximately 5% in immature cells observed in granulomatous areas. We thus suspected a coexisting neoplastic component. The residual lesion persisted in a dormant state for 2 years following biopsy. Surgical resection of a lipoma is extremely difficult and potentially dangerous. However, in the present case, the lesion was accompanied by atypical, expanding, and perifocal edema. Surgical treatment was inevitable for the purpose of histological confirmation, considering differential diagnoses such as dermoid, epidermoid, and glioma. In the end, anticonvulsant therapy proved effective for controlling epileptic seizures.

  13. Teaching Presentation Skills

    Science.gov (United States)

    Baker, William H.; Thompson, Michael P.

    2004-01-01

    Effective teaching of presentation skills focuses on the most important element of the presentation--the message itself. Some instructors place the heaviest emphasis on the messenger (the presenter) and focus their presentation feedback on all the presenter is doing wrong--saying "um," gesturing awkwardly, and so forth. When students receive this…

  14. Cardiac syncope induced by glossopharyngeal "neuralgia": a rare presentation.

    Science.gov (United States)

    Korkes, Helio; de Oliveira, Eduardo Mesquita; Brollo, Luigi; Hachul, Denise Tessariol; Andrade, José Carlos da Silva; Peres, Mario Fernando Prieto; Schubsky, Victor

    2006-11-01

    The first description of severe pain in the distribution of the glossopharyngeal nerve is credited to Weisenberg, in 1910, in a patient with cerebellopontine angle tumor. However, it was Harris, in 1926, who coined the term glossopharyngeal neuralgia to describe this rare condition characterized by paroxysms of excruciating pain located laterally at the back of the tongue, soft palate, throat, and lateral and posterior pharynx, radiating to the ear. Swallowing, coughing, yawning or chewing may trigger pain, which usually lasts from seconds to minutes. The association between glossopharyngeal neuralgia and syncope is very rare, being identified by brief episodes of bradycardia, asystole, and hypotension. Such an association, with this same pathophysiology, was first described by Riley et al in 1942. PMID:17396191

  15. Workshop Presentations: Overviews

    Data.gov (United States)

    National Aeronautics and Space Administration — These slides were presented at the AePW, April 21-22, 2012. Additional presentations can be found on each of the associated analysis webpages. Separate pages...

  16. The Art of Presenting.

    Science.gov (United States)

    Lukey-Coutsocostas, Kathryn; Tanner-Bogia, Julia

    1998-01-01

    Provides suggestions for helping nonnative English speakers in planning and delivering an effective presentation. Topics covered include the following: fears, choosing a topic, planning, title/summary/abstract, equipment, delivery, and evaluation of the present. (Author/VWL)

  17. Renewable Electricity Futures (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Mai, T.

    2012-08-01

    This presentation summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. This presentation was presented in a Wind Powering America webinar on August 15, 2012 and is now available through the Wind Powering America website.

  18. Presenting Food Science Effectively

    Science.gov (United States)

    Winter, Carl K.

    2016-01-01

    While the need to present food science information effectively is viewed as a critical competency for food scientists by the Institute of Food Technologists, most food scientists may not receive adequate training in this area. Effective presentations combine both scientific content and delivery mechanisms that demonstrate presenter enthusiasm for…

  19. Innovative presentations for dummies

    CERN Document Server

    Anthony, Ray

    2014-01-01

    Be the speaker they follow with breakthrough innovative presentations Innovative Presentations For Dummies is a practical guide to engaging your audience with superior, creative, and ultra-compelling presentations. Using clear language and a concise style, this book goes way beyond PowerPoint to enable you to reimagine, reinvent, and remake your presentations. Learn how to stimulate, capture, and hold your audience in the palm of your hand with sound, sight, and touch, and get up to speed on the latest presentation design methods that make you a speaker who gets audiences committed and acting

  20. Laser Actuated Presentation System

    OpenAIRE

    Chowdhary, Atul; Agrawal, Vivek; Karmakar, Subhajit; Sarkar, Sandip

    2009-01-01

    We present here a pattern sensitive PowerPoint presentation scheme. The presentation is actuated by simple patterns drawn on the presentation screen by a laser pointer. A specific pattern corresponds to a particular command required to operate the presentation. Laser spot on the screen is captured by a RGB webcam with a red filter mounted, and its location is identified at the blue layer of each captured frame by estimating the mean position of the pixels whose intensity is above a given thre...

  1. Laser Actuated Presentation System

    CERN Document Server

    Chowdhary, Atul; Karmakar, Subhajit; Sarkar, Sandip

    2009-01-01

    We present here a pattern sensitive PowerPoint presentation scheme. The presentation is actuated by simple patterns drawn on the presentation screen by a laser pointer. A specific pattern corresponds to a particular command required to operate the presentation. Laser spot on the screen is captured by a RGB webcam with a red filter mounted, and its location is identified at the blue layer of each captured frame by estimating the mean position of the pixels whose intensity is above a given threshold value. Measured Reliability, Accuracy and Latency of our system are 90%, 10 pixels (in the worst case) and 38 ms respectively.

  2. Alarm filtering and presentation

    International Nuclear Information System (INIS)

    This paper discusses alarm filtering and presentation in the control room of nuclear and other process control plants. Alarm generation and presentation is widely recognized as a general process control problem. Alarm systems often fail to provide meaningful alarms to operators. Alarm generation and presentation is an area in which computer aiding is feasible and provides clear benefits. Therefore, researchers have developed several computerized alarm filtering and presentation approaches. This paper discusses problems associated with alarm generation and presentation. Approaches to improving the alarm situation and installation issues of alarm system improvements are discussed. The impact of artificial intelligence (AI) technology on alarm system improvements is assessed. (orig.)

  3. Leprosy neuropathy: clinical presentations.

    Science.gov (United States)

    Nascimento, Osvaldo J M

    2013-09-01

    Leprosy is a chronic infectious peripheral neuropathy caused by Mycobacterium leprae. The different clinical presentations of the disease are determined by the quality of the host immune response. Early detection of leprosy and treatment by multidrug therapy are the most important steps in preventing deformity and disability. Thus the early recognition of the clinical leprosy presentation is essential. Mononeuritis, mononeuritis multiplex (MM), polyneuritis (MM summation) are the most frequent. The frequent anesthetic skin lesions are absent in the pure neuritic leprosy presentation form. Isolated peripheral nerve involvement is common, including the cranial ones. Arthritic presentation is occasionally seen, usually misdiagnosed as rheumatoid arthritis. Attention should be given to autonomic dysfunctions in leprosy. There are clinical presentations with severe neuropathic pain - painful small-fiber neuropathy. Leprous late-onset neuropathy (LLON) clinical presentation should be considered facing a patient who develop an inflammatory neuropathy many years after a previous skin leprosy treatment. PMID:24141500

  4. CERN Electronics Pool presentations

    CERN Multimedia

    2011-01-01

    The CERN Electronics Pool has organised a series of presentations in collaboration with oscilloscope manufacturers. The last one will take place according to the schedule below.   Time will be available at the end of the presentation to discuss your personal needs. The Agilent presentation had to be postponed and will be organised later. -     Lecroy: Thursday, 24 November 2011, in 530-R-030, 14:00 to 16:30.

  5. Product presentation on DVD

    OpenAIRE

    Willsund, John

    2008-01-01

    The purpose of this thesis is to seek answers to the questions how the sales in a photo shop can be affected by animated commercial presentations and what the costs of producing such presentations would be. The costs are calculated from three different scenarios. The presentations produced has been for one single camera model and for selected products within three product groups; binoculars, digital cameras and printed matters. The task has included image processing of self-shot and existing ...

  6. Conns' syndrome - atypical presentations

    International Nuclear Information System (INIS)

    Primary hyperaldosteronism (Conns' syndrome) commonly presents with a combination of clinical features of hypokalemia and hypertension. Atypical presentations like normotension, normokalemia and neurological ailments are described in few cases. We encountered two such cases, the first presenting with acute neurological complaint and second case having insignificant hypertension. Both the patients had a characteristic biochemical and imaging profile consistent with primary hyperaldosteronism and responded to surgical resection of adrenal adenoma. (author)

  7. Presentation skills for nurses.

    Science.gov (United States)

    Foulkes, Mark

    2015-02-20

    This article emphasises the importance of effective presentation skills. Such skills allow nurses to share knowledge and expertise and to communicate clearly in a range of workplace scenarios. Nurses are increasingly being asked to present in formal and informal situations, such as conferences, poster presentations, job interviews, case reports and ward-based teaching. This article explores the principles underpinning the development of these skills, discusses the situations in which they could be applied and demonstrates how nurses might improve and develop as presenters. PMID:25690236

  8. Renewable Electricity Futures (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Mai, T.

    2012-08-01

    This presentation summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. It was presented in a Power Systems Engineering Research Center webinar on September 4, 2012.

  9. Renewable Electricity Futures (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Hand, M.; Mai, T.

    2012-08-01

    This presentation library summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. It was presented in an Union of Concerned Scientists webinar on June 12, 2012.

  10. Unusual presentation of a dermoid cyst in the ischiorectal fossa. Magnetic resonance imaging and ultrasound appearances

    Energy Technology Data Exchange (ETDEWEB)

    Choudur, H.N. [Hamilton General Hospital, Department of Radiology, Hamilton, ON (Canada); Hamilton General Hospital, McMaster University, Department of Diagnostic Imaging, Hamilton Health Sciences, Hamilton, Ontario (Canada); Hunjan, J.S.; Howey, J.M. [Hamilton General Hospital, McMaster University, Department of Diagnostic Imaging, Hamilton Health Sciences, Hamilton, Ontario (Canada); DeNardi, F. [Henderson General Hospital, McMaster University, Department of Diagnostic Imaging, Hamilton Health Sciences, Hamilton, Ontario (Canada)

    2009-09-15

    The ischiorectal fossa may give rise to a wide variety of pathological entities, although it is composed of relatively few structures. Developmental cysts are included among the list. Large epidermoid cysts in the ischiorectal fossa have been previously described (Fujimoto et al., Clin Imaging 17:146-148, 1993; Ng et al., Can J Surg 49:435-436, 2006). However, to the best of our knowledge, there is no published case in the English literature of a dermoid cyst within the ischiorectal fossa. Using magnetic resonance (MR) imaging and a subsequent ultrasound-guided biopsy, we were able to offer a focused differential that included a dermoid cyst within the ischiorectal fossa in a 55-year-old man presenting with a painful mass on the buttocks. Hair and fatty components were obtained by targeted ultrasound-guided biopsy. On MR imaging, the mass was seen to be well circumscribed and registered a heterogeneous T1-weighted signal that corresponded to layers of fat and debris on short-tau inversion recovery (STIR) imaging. A well-defined ball of fat was noted centrally within the lesion, with a speckled low T1 and low T2 signal within it. Hair admixed with fat was obtained from it by targeted ultrasound-guided biopsy. There was no enhancement of the lesion after administration of gadolinium. On ultrasound, the lesion was well circumscribed and heterogeneous; the echogenic area corresponded to the fat signal seen on magnetic resonance imaging (MRI). The lower level echoes within the lesion corresponded to the debris seen on MRI. The central rounded area of speckling, registering fine posterior shadowing corresponded to the hairy contents obtained by the targeted ultrasound-guided biopsy. A differential diagnosis of all lipomatous lesions was included in the pre-biopsy report: fat necrosis within a lipoma; well-differentiated liposarcoma; myxoid liposarcoma and dermoid cyst. Histopathological diagnosis following complete surgical resection was that of a dermoid cyst. (orig.)

  11. Pseudoxanthoma elasticum. Case presentation

    Directory of Open Access Journals (Sweden)

    Graciela Caridad Cabrera Acea

    2009-05-01

    Full Text Available The case of a female patient of 23 years of age is presented. The patient attended to the dermatology consultation in her health area for skin lesions in the neck area, of 10 years of evolution with new lesions after three years in different parts of her body (armpits, periumbilical, vaginal and rectal regions. These lesions present an aspect similar to orange skin, surrounded by yellow papules. the diagnosis was pseudoxanthoma elasticum after the clinical and histopathological analysis, and the perimetry. We present this case since this is an infrequent disease and for the importance of an early diagnosis of skin lesions in a systemic disease.

  12. Heterotrophic Pregnancy- Rare Presentation

    Directory of Open Access Journals (Sweden)

    AB Chattopadhyay

    2013-06-01

    Full Text Available Heterotopic pregnancy, a potentially dangerous and life-threatening clinical associated with intrauterine (IU and extra uterine pregnancies at the same time. Incidence of such cases are rare but very often missed as the diagnosis being overlooked during examination of the pregnant women with risk factors for an ectopic pregnancy such as free fluid with or without an adnexal mass or acute abdominal pain and shock presentation. Hence a high degree of clinical evaluation is warranted examining the pregnant women. In Present paper we report a case with rare presentation as heterotopic pregnancy from emergency hospital of teaching hospital.

  13. Practically Perfect Presentations.

    Science.gov (United States)

    Harris, Richard M.

    1994-01-01

    Offers nine practical suggestions for instructional presentations: build a sense of partnership, ask rhetorical questions, be spontaneous, use a conversational tone, control tone of voice, involve listener through gesture, be creative, be relevant, and achieve clarity. (JOW)

  14. Doctoral Research Presentations

    OpenAIRE

    Thomson, Alison; Plummer-Fernandez, Matthew; Yurman, Paulina; Migliore, Enza; Gray, Nicola; Yang, Ya-huei; Hogan, Nicola; Kerridge, Tobie

    2015-01-01

    The Department of Design has a thriving community of scholars and practitioners engaged in doctoral research. In this session students,graduates and visiting researchers will present their research covering a broad range of topics and research interests.

  15. Ovarian Cysts. Case Presentation

    International Nuclear Information System (INIS)

    We present the clinical case of a 50 days old girl, born with cystic ovaries, secondary to hormonal stimulation. The clinical diagnosis and management is described and a revision of the literature is made.

  16. Workshop Presentations: BSCW Analysts

    Data.gov (United States)

    National Aeronautics and Space Administration — These slides were presented at the AePW, April 21-22, 2012. They detail the analytical results generated by each of the participating analysis teams for the...

  17. Workshop Presentations: RSW Analysts

    Data.gov (United States)

    National Aeronautics and Space Administration — These slides were presented at the AePW, April 21-22, 2012. They detail the analytical results generated by each of the participating analysis teams for the...

  18. Workshop Presentations: HIRENASD Analysts

    Data.gov (United States)

    National Aeronautics and Space Administration — These slides were presented at the AePW, April 21-22, 2012. They detail the analytical results generated by each of the participating analysis teams for the HIRENASD.

  19. Renewable Electricity Futures (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Mai, T.

    2012-10-01

    This presentation library summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050.

  20. ARE YOU PRESENT?

    OpenAIRE

    Juul, Henrik; Gilmartin, Thomas; Thomas, Thomas Tom

    2007-01-01

    Master of Computer Mediated Comunication thesis: ARE YOU PRESENT? FROM SPECTATOR TO PARTICIPANT IN COMPUTER MEDIATED CONFERENCES This thesis analyzes the application of Social Presence theory on a conference with participants attending online in UNDP and the consequences hereof.

  1. Presenting New Grammar

    Institute of Scientific and Technical Information of China (English)

    WU Cai-ling; WANG Xi

    2015-01-01

    More and more researchers have now agreed upon the necessity of teaching grammar, but it still remains controversial as how to teach the forms, with the central consideration of not to harm the meaning-focused communicative teaching method. In this essay, one of the issues in grammar teaching will be discussed as how to present new grammar to learners, through evaluating and modifying a particular presentation activity in a grammar-teaching textbook.

  2. Tritium monitoring : present status

    International Nuclear Information System (INIS)

    The report summarizes the present status of techniques employed for the monitoring of tritium in water, air and other samples. A brief mention of the work done by numerous workers in the field, critical comments about the work and a fairly exhaustive list of references about the work done during the last 4 decades has been presented. On-line monitoring on real time basis in nuclear reactors is also discussed. (author). 83 refs., 10 refs., 2 tabs

  3. SIRENOMELIA A RARE PRESENTATION

    OpenAIRE

    K. Ramesh Reddy; Srinivas, S; Shiva Kumar; Surweshwar Reddy; Hariprasad; G M Irfan

    2012-01-01

    We are presenting two cases of Sirenomelia (Mermaid Syndrome), which is an extreme example of the caudal regression syndrome. It invariably presents with lower limb fusion, sacral and pelvic bony anomalies, absent external genitalia, imperforate anus, and renal agenesis or dysgenesis. There are approximately 300 cases reported in the literature, 15% of which are associated with twinning, most often monozygotic. The syndrome of caudal regression is thought to be the result of injury to the cau...

  4. Present status of dibaryons

    International Nuclear Information System (INIS)

    In the present notes the author tries to assess the situation regarding dibaryons in the various channels with baryon number two, emphasizing the problems and discussing in greater detail the most recent developments since the Versailles Conference. One of the motivations for the present search of B=2 states is the possibility of colored subclusters for systems with six quarks which cannot occur for ordinary baryons or mesons. (Auth.)

  5. The colonial present

    OpenAIRE

    Bunnell, Tim

    2006-01-01

    cultural geographies 2006 13: 305-312 reviews in brief The colonial present. By Derek Gregory. Malden, MA: Blackwell. 2004. 367 pp. £16.99 paper. ISBN 1577180909. The colonial present extends and deepens our understanding of contemporary geopolitics in ways that speak to the key concerns of this journal. For Derek Gregory as for Edward Said, to whom the book is dedicated, and whose intellectual legacy runs through its pages - issues of cu...

  6. Blade Testing Trends (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Desmond, M.

    2014-08-01

    As an invited guest speaker, Michael Desmond presented on NREL's NWTC structural testing methods and capabilities at the 2014 Sandia Blade Workshop held on August 26-28, 2014 in Albuquerque, NM. Although dynamometer and field testing capabilities were mentioned, the presentation focused primarily on wind turbine blade testing, including descriptions and capabilities for accredited certification testing, historical methodology and technology deployment, and current research and development activities.

  7. Leprosy: An unusual presentation

    Directory of Open Access Journals (Sweden)

    Geeta Kiran Arakkal

    2015-01-01

    Full Text Available Leprosy is a chronic infectious disease caused by Mycobacterium leprae, commonly manifesting as hypopigmented anesthetic patches with thickened nerves. Primary hyperpigmentation in leprosy is a rare manifestation. Literature search showed only few case reports of Hansen's disease with single hyperpigmented patch and involvement of relatively immune zones like palms and soles. We report a case of leprosy presenting primarily as hyperpigmented patches over the trunk and extremities with involvement of palms and soles which is a rare presentation.

  8. Communication and presentation skills

    OpenAIRE

    Lorencová, Ivana

    2014-01-01

    This bachelor thesis deals with individual factors of communication and basic presentations skills. The theoretical part specifies the basic elements of verbal and non-verbal communication and basic factors connected with preparation and realisation of a presentation. The practical part of the thesis comprises an analysis of impacts of speaker's visual and other communication influences over an audience. The results are applied to a Multimedia Display exhibition taking place during the bachel...

  9. Stellar Presentations (Abstract)

    Science.gov (United States)

    Young, D.

    2015-12-01

    (Abstract only) The AAVSO is in the process of expanding its education, outreach and speakers bureau program. powerpoint presentations prepared for specific target audiences such as AAVSO members, educators, students, the general public, and Science Olympiad teams, coaches, event supervisors, and state directors will be available online for members to use. The presentations range from specific and general content relating to stellar evolution and variable stars to specific activities for a workshop environment. A presentation—even with a general topic—that works for high school students will not work for educators, Science Olympiad teams, or the general public. Each audience is unique and requires a different approach. The current environment necessitates presentations that are captivating for a younger generation that is embedded in a highly visual and sound-bite world of social media, twitter and U-Tube, and mobile devices. For educators, presentations and workshops for themselves and their students must support the Next Generation Science Standards (NGSS), the Common Core Content Standards, and the Science Technology, Engineering and Mathematics (STEM) initiative. Current best practices for developing relevant and engaging powerpoint presentations to deliver information to a variety of targeted audiences will be presented along with several examples.

  10. Dermatofibroma: Atypical presentations

    Directory of Open Access Journals (Sweden)

    Mousumi Roy Bandyopadhyay

    2016-01-01

    Full Text Available Dermatofibroma is a common benign fibrohistiocytic tumor and its diagnosis is easy when it presents classical clinicopathological features. However, a dermatofibroma may show a wide variety of clinicopathological variants and, therefore, the diagnosis may be difficult. The typical dermatofibroma generally occurs as a single or multiple firm reddish-brown nodules. We report here two atypical presentations of dermatofibroma - Atrophic dermatofibroma and keloidal presentation of dermatofibroma. Clinical dermal atrophy is a common phenomenon in dermatofibromas as demonstrated by the dimpling on lateral pressure. However, this feature is exaggerated in the atrophic variant of dermatofibroma. Atrophic dermatofibroma is defined by dermal atrophy of more than 50% of the lesion apart from the usual features of common dermatofibroma. The keloidal variant of dermatofibroma should not be overlooked as a simple keloid. The findings of keloidal change in dermatofibromas may support that trauma is a possible cause of dermatofibroma.

  11. Dermatofibroma: Atypical Presentations.

    Science.gov (United States)

    Bandyopadhyay, Mousumi Roy; Besra, Mrinal; Dutta, Somasree; Sarkar, Somnath

    2016-01-01

    Dermatofibroma is a common benign fibrohistiocytic tumor and its diagnosis is easy when it presents classical clinicopathological features. However, a dermatofibroma may show a wide variety of clinicopathological variants and, therefore, the diagnosis may be difficult. The typical dermatofibroma generally occurs as a single or multiple firm reddish-brown nodules. We report here two atypical presentations of dermatofibroma - Atrophic dermatofibroma and keloidal presentation of dermatofibroma. Clinical dermal atrophy is a common phenomenon in dermatofibromas as demonstrated by the dimpling on lateral pressure. However, this feature is exaggerated in the atrophic variant of dermatofibroma. Atrophic dermatofibroma is defined by dermal atrophy of more than 50% of the lesion apart from the usual features of common dermatofibroma. The keloidal variant of dermatofibroma should not be overlooked as a simple keloid. The findings of keloidal change in dermatofibromas may support that trauma is a possible cause of dermatofibroma. PMID:26955137

  12. Analyzing in the Present

    DEFF Research Database (Denmark)

    Revsbæk, Line; Pedersen, Lene Tanggaard

    2015-01-01

    The article presents a notion of “analyzing in the present” as a source of inspiration in analyzing qualitative research materials. The term emerged from extensive listening to interview recordings during everyday commuting to university campus. Paying attention to the way different parts of...... various interviews conveyed diverse significance to the listening researcher at different times became a method of continuously opening up the empirical material in a reflexive, breakdown-oriented process of analysis. We argue that situating analysis in the present of analyzing emphasizes and acknowledges...... contributes to an ongoing methodological conversation problematizing the notion of “data” and the use of “data-reliant” methods of analysis....

  13. Book Presentation | 27 February

    CERN Multimedia

    The CERN Library

    2013-01-01

    "A caccia del bosone di Higgs. Magneti, governi, scienziati e particelle nell'impresa scientifica del secolo" by Luciano Maiani and Romeo Bassoli, published by Mondadori. On Wednesday 27 February Luciano Maiani will present the book "A caccia del bosone di Higgs. Magneti, governi, scienziati e particelle nell'impresa scientifica del secolo". More information here. The presentation will take place in the Council Chamber at 16.00 and will be followed by a debate and book signing. The book will be on sale. You are cordially invited.

  14. Renewable Electricity Futures (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Mai, T.

    2012-08-01

    This presentation library summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. It was presented at the 2012 RE AMP Annual Meeting. RE-AMP is an active network of 144 nonprofits and foundations across eight Midwestern states working on climate change and energy policy with the goal of reducing global warming pollution economy-wide 80% by 2050.

  15. Round table presentation

    International Nuclear Information System (INIS)

    Considerations on radiological protection always start off with discussions on concepts, principles and other basic assumptions. We are all aware of the fact that the International Commission on Radiological Protection (ICRP) is currently holding such discussions. They are useful for corporate radiological protection if they lead to rules and regulations which meet practical everyday requirements. In the topical sessions, papers have been presented on the implementation of 'basic safety standards' and corporate radiological protection in medical institutions, research institutions, technical plants and nuclear power stations. Some of these contributions were followed by discussions. In this presentation I would like to come back to some of the items raised in these discussions

  16. Presentation of 2004 earnings

    International Nuclear Information System (INIS)

    This presentation offers financial information on the AREVA Group earnings for the year 2004. With manufacturing facilities in over 40 countries and a sales network in over 100, Areva offers customers technological solutions for nuclear power generation and electricity transmission and distribution. The Group also provides interconnect systems to the telecommunications, computer and automotive markets. (A.L.B.)

  17. Agriculture Oral Presentations

    International Nuclear Information System (INIS)

    This publication contains 23 papers related to the use of nuclear techniques in plant breeding in Turkey, effect of gamma irradiations on growing various plants, mutations and soil chemistry, etc., presented at 4. International Congress of Nuclear Agriculture and Animal Science in Bursa, Turkey, 25-27 Sep 1996. A separate abstract was prepared for each paper

  18. Presentation of 2004 earnings

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-03-01

    This presentation offers financial information on the AREVA Group earnings for the year 2004. With manufacturing facilities in over 40 countries and a sales network in over 100, Areva offers customers technological solutions for nuclear power generation and electricity transmission and distribution. The Group also provides interconnect systems to the telecommunications, computer and automotive markets. (A.L.B.)

  19. Keynote presentation : SAR systems

    NARCIS (Netherlands)

    Halsema, D. van; Otten, M.P.G.; Maas, A.P.M.; Bolt, R.J.; Anitori, L.

    2011-01-01

    Synthetic Aperture Radar (SAR) systems are becoming increasingly important sensors in as well the military environment as in the civilian market. In this keynote presentation an overview will be given over more than 2 decades of SAR system∼ and SAR application development at TNO in the Netherlands.

  20. Managing Presentation Anxiety

    Science.gov (United States)

    Hartman, Jackie L.; LeMay, Elaine

    2004-01-01

    All business communication professors struggle with anxiety-ridden students when discussing public speaking. To alleviate students' fears of speaking in public a process was designed to allow business communication students to acknowledge, address, and annul their presentation fears. A six-year comparative study using qualitative methods and…

  1. Intraductal Papilloma: Atypical Presentation

    OpenAIRE

    P Ramaswamy; Tanya Khaitan; Anuradha, A.; B Praveen Kumar; Sudhakar, S.

    2013-01-01

    Ductal papillomas have unique papillary features arising from the salivary gland duct system. They comprise three rare benign adenomas, namely, inverted ductal papilloma, sialadenoma papilliferum, and intraductal papilloma. Intraductal papilloma is an extremely rare benign salivary gland tumor that occurs most commonly in the minor salivary glands. Here, we are presenting a case report of intraductal papilloma in an 18-year-old patient.

  2. Neurosyphilis: Various Presentations

    Directory of Open Access Journals (Sweden)

    Kezban Aslan

    2012-12-01

    Full Text Available Neurosphylisis develops in about 5 % of untreated patients infected with Treponema pallidum. Spirocet, disseminates systemically hours to days after inoculation. Early invasion to central nervous system can be seen in infected patients without symptomatic. In these lecture we presented three patients with different complain. The patients have had; diplopia, headache and blurred vision, numness and slimming of legs.

  3. Carcinoma epidermoide (variante pequenas células vs. carcinoma de pequenas células do pulmão: diagnóstico diferencial em material de biópsia Small cell variant of squamous cell carcinoma vs. small cell carcinoma of the lung: differential diagnosis in biopsies

    Directory of Open Access Journals (Sweden)

    Rachel Martins Marinho

    2010-04-01

    Full Text Available O diagnóstico diferencial entre a variante pequenas células do carcinoma epidermoide e do carcinoma de pequenas células nem sempre é fácil. Apesar de os descritores alertarem que o primeiro deva manter suas características morfológicas e, muitas vezes, diferenciação escamosa focal, a escassez de material aliada a artefatos de fixação frequentes nessas biópsias podem dificultar a vida do patologista. Entretanto, a definição entre um e outro pode alterar significativamente a escolha da modalidade terapêutica do paciente e, em alguns casos, influenciar seu prognóstico. Procuramos nesta publicação alertar para o problema e facilitar essa diferenciação, sugerindo um painel imuno-histoquímico.The differential diagnosis between small cell variant of squamous carcinoma and small cell carcinoma is not always simple. Despite the fact that studies show the former keeps its morphologic characteristics and focal squamous differentiation, the scarcity of the material as well as frequent fixation artifacts in these biopsies may hinder analysis. However, this differentiation between them may change significantly the choice of therapeutic approach and, in some cases, influence prognosis. In this paper, we draw attention to this problem and suggest a immunohistochemical panel to facilitate this differential diagnosis.

  4. Summary of the presentations

    International Nuclear Information System (INIS)

    This part summarizes the content of the six following presentations: 1. IAEA requirements/guidance for the decommissioning safety case (Mike Bell, IAEA); 2. Safety case in an EIA context (Patrick O'SULLIVAN, The Netherlands); 3. Plant configuration and the D and D licensing process (Eugenio GIL LOPEZ and Pedro CARBONERAS, Spain); 4. Accident assessment (Ivo TRIPPUTI, Italy; Ingmar LUND, Sweden); 5. Balancing radiological and industrial risk in the safety case (Pascal DEBOODT, Belgium); 6. The safety case for safe store and dormancy periods (Paul WOOLLAM, UK). Following the six presentations, the WPDD members discussed the safety case in an open discussion led by the Topical Session Chair, Frances Taylor. The discussion was wide-ranging, and topics varied from the standards that apply to releases to the environment during safe store, to decommissioning parallels with other major processing industries and facilities (such as oil rigs). Frances Taylor steered the discussion toward addressing the questions that the WPDD Core Group had proposed for the topical session. The Chair, the Rapporteur, and some members of the group sensed that the presentations had covered such an wide variety of issues, and that the content of the presentations themselves differed so greatly, that it would be difficult to distill a position paper from the information gathered, as had been the mandate from the Core Group. In addition, the meaning of the term 'Safety Case' differed greatly among participants in the topical session. Some took the term to mean the analysis and document that the implementor provides to the regulator, describing how operations will be performed safely. Others considered the term to mean the overall safety and risk conditions inherent in a nuclear facility during operations or decommissioning. With the differences in presentations and with the meaning of the terminology remaining unclear, the WPDD participants did not reach consensus conclusions on December 5, 2001

  5. SIRENOMELIA A RARE PRESENTATION

    Directory of Open Access Journals (Sweden)

    K Ramesh Reddy

    2012-01-01

    Full Text Available We are presenting two cases of Sirenomelia (Mermaid Syndrome, which is an extreme example of the caudal regression syndrome. It invariably presents with lower limb fusion, sacral and pelvic bony anomalies, absent external genitalia, imperforate anus, and renal agenesis or dysgenesis. There are approximately 300 cases reported in the literature, 15% of which are associated with twinning, most often monozygotic. The syndrome of caudal regression is thought to be the result of injury to the caudal mesoderm early in gestation. One of our cases survived for 12 days after birth. This new born had an unusually high anorectal anomaly in which the colon was ending at the level of mid transverse colon, fused lower limbs and genital anomalies. Ultrasound of the abdomen revealed horseshoe kidney. Colostomy was performed on day 2 of life. The second case encountered was a stillborn baby on whom an autopsy was performed.

  6. El escenario del presente

    Directory of Open Access Journals (Sweden)

    Cruz, Manuel

    2008-12-01

    Full Text Available The disappearance of the idea of progress in post-Enlightenment thought constitutes one of the central tenets of the network of topics that make up contemporary social imagery. However, that tenet, which in a sense has been present from the origins of the Enlightment tradition, produces discursive effects of significant relevance, a particular kind of perverse effects related to thought, not always legitimized enough to certify that disappearance.

    La desaparición de la idea de progreso en el pensamiento postilustrado constituye uno de los convencimientos centrales del entramado de tópicos que forman el imaginario social contemporáneo. Pero dicho convencimiento, en cierto modo presente desde los orígenes de la propia tradición ilustrada, da lugar a efectos discursivos de considerable importancia, a una particular modalidad de efectos perversos en materia de pensamiento, no siempre suficientemente aquilatados al certificar dicha desaparición.

  7. Conversation VS Presentation

    Institute of Scientific and Technical Information of China (English)

    侯克为

    2015-01-01

    <正>It is always said that a good teacher should be a good lecturer.He or she should at least master all the different methods of presenting a good presentation to students.We expect our teachers to give a wonderful lecture in class and that’s everything a successful teacher should do.However,is this truly right?Does it really make sense that a teacher should be a lecturer and treat our students as audiences in class?No,I don’t think so.Especially after all these years of teaching primary and middle school students,I think a successful teacher should be a good talker.They should always know how

  8. Heterotrophic Pregnancy- Rare Presentation

    OpenAIRE

    AB Chattopadhyay; Somshekhar Sharma; Kushagra Garg

    2013-01-01

    Heterotopic pregnancy, a potentially dangerous and life-threatening clinical associated with intrauterine (IU) and extra uterine pregnancies at the same time. Incidence of such cases are rare but very often missed as the diagnosis being overlooked during examination of the pregnant women with risk factors for an ectopic pregnancy such as free fluid with or without an adnexal mass or acute abdominal pain and shock presentation. Hence a high degree of clinical evaluation is warranted examining ...

  9. Choriocarcinoma presenting with thyrotoxicosis

    OpenAIRE

    Sotello, David; Rivas, Ana Marcella; Test, Victor J.; Lado-Abeal, Joaquin

    2016-01-01

    We describe a 26-year-old man with metastatic choriocarcinoma who presented with hyperthyroidism associated with elevated β-human chorionic gonadotropin (B-HCG) and respiratory failure secondary to diffuse lung metastasis. After the first cycle of chemotherapy, the concentration of B-HCG dramatically decreased and the patient became euthyroid, allowing us to discontinue antithyroid medications. The patient's hyperthyroidism was caused by stimulation of the thyroid gland by high B-HCG levels, ...

  10. Practical modes of presentation

    OpenAIRE

    Glick, E.

    2015-01-01

    The Intellectualist thesis that know-how is a kind of propositional knowledge faces a simple problem: For any proposition p, it seems that one could know p without knowing how to do the activity in question. For example, it seems that one could know that w is a way to swim even if one didn't know how to swim oneself. In this paper I argue that this "sufficiency problem" cannot be adequately addressed by appealing to practical modes of presentation.

  11. Presentation = Speech + Slides

    Directory of Open Access Journals (Sweden)

    Derik Badman

    2008-12-01

    Full Text Available Back in October, Aaron Schmidt posted “HOWTO give a good presentation” to his blog walking paper. His second bullet point of “thoughts” on good presentations is: Please don’t fill your slides with words. Find some relevant and pretty pictures to support what you’re saying. You can use the pictures to remind yourself what you’re going [...

  12. INTERVIEWS : PRESENTING YOU

    OpenAIRE

    ブリトン, ジョセフ; Britton, Joseph

    2005-01-01

    The conclusions drawn in this paper are based upon more than 30 years of personal research along with the findings of communication firms and media consultants whose business is to influence our opinions. To quantify the success rate of implementing particular methods of interviewee presentations is a most difficult challenge often wrought with the bias of the researcher. This author has instead drawn conclusions about successful interviews based upon the fundamental questions asked by leadin...

  13. Presentation of the journal.

    OpenAIRE

    Hernández, Esteban

    2004-01-01

    The recent upsurge in the volume and quality of the accounting history research in Spain has positioned it as one of the top nations in the field. However, only two Spanish journals are now dedicated entirely to accounting, and, while some Spanish accounting history researchers do publish part of their work in English language journals, publication continues to be a difficult proposition for most. Thus, many researchers can hope only to present their work as papers at Conferences and Congress...

  14. Unusual presentation of phaeochromocytoma.

    Science.gov (United States)

    Hope, D C D; Palan, J M

    2016-01-01

    A 44-year-old woman, with a background of heart, lung and renal transplantation secondary to cystic fibrosis and type 1 diabetes, presented with tachycardia, hyperglycaemia, nausea and vomiting. She was initially managed for diabetic ketoacidosis with severe dehydration. However, persistent episodic hypertension and tachycardia led the investigating team to identify significantly raised urinary metanephrines and a left-sided adrenal mass; Iodine-123-meta-iodobenzylguanidine single photon emission computer tomography scan (MIBG SPECT/CT) showed avid uptake of tracer, confirming a left-sided phaeochromocytoma. She was started on medical management and is awaiting an elective laparoscopic procedure. This case describes the presentation of a unilateral phaeochromocytoma as ketoacidosis in a patient with type 1 diabetes with no other apparent precipitant. This highlights the metabolic counter-regulatory effect of excess catecholamines in addition to the inotropic/chronotropic effects that are associated with this adrenal tumour. Recognition of atypical signs and symptoms may point towards an atypical precipitant of diabetic ketoacidosis-a medical emergency presenting to front-line clinicians. PMID:27166010

  15. Retinoblastoma presenting as metastasis

    International Nuclear Information System (INIS)

    Objective: The purpose of this study was to evaluate the frequency of metastatic retinoblastoma on initial presentation. Design: Prospective study. Place and duration of study: Supra Regional Centre for Retinoblastoma, Department of Ophthalmology, Khyber Teaching Hospital Peshawar Pakistan from July 1, 1999 to January 31, 2003. Methods: Data was collected from 80 registered Retinoblastoma patients admitted and examined under anaesthesia for tumours assessment. Diagnosis was supported with the help of CT scan and confirmed by histopathology of the enucleated specimen for evidence of optic nerve invasion by the tumour. Results: Twenty (25%) patients were presenting as Metastasis on initial presentation. Mean age was 3.5 years, range was 7 months to 12 years. Out of these 20 patients with metastasis, 10 were male and 10 were female. Eighteen (90%) of them were from lower socio-economic group. Conclusion: Failure in early diagnosis of retinoblastoma, advance age and unilateral disease are associated with extraocular spread; this tragic scenario can be prevented best be early detection and prompt treatment plan implementation. (author)

  16. Tuberous Sclerosis: Multiple Presentations

    Directory of Open Access Journals (Sweden)

    M. Sanei Taheri

    2008-01-01

    Full Text Available Introduction: Tuberous sclerosis is an autosomal do-minant genetic disorder that involves multiple or-gans. The predominant lesions are the hamartomas. Classically tuberous sclerosis has been characterized by a classic clinical triad of facial angiofibromas in 90%,retardation in 50-80%,seizure 80-90% and all three in 30%."nThe disease occurs in 1:100,000 persons in all races with nearly equal distribution between the sexes. "nCase Presentation: We had six patients who admitted with different presentations of tuberous sclerosis with a past history of convulsion from childhood, skin le-sions and mental retardation, also with new onset headache and changed pattern of convulsion. In physical examination facial angiofibromas and sub-ungual fibromas apparently detected. Brain CT scan study with contrast showed multiple calcified nod-ules associated with tubers and ventriculomegaly, also an enhancing enlarged nodule at foramen of mo-nro, which was suggestive of subependymal giant cell astrocytoma (SGCA. In abdominal and pelvic CT scan and ultrasonography, massive bilateral angio-myolipomatosis diagnosed. Also Focal hypodense le-sions in liver which were hyperechoic in ultrasono-graphy were diagnosed. With MRI study tubers, white matter lesions and subependymal nodules asso-ciated with SGCA were detected better. After surgery SGCA was proved."nDiscussion: Our patients had different presentations and various findings of this spectrum discussed in this lecture.

  17. Liponeurocytoma Cerebellar. A new entity; first national case

    International Nuclear Information System (INIS)

    The first case of this new entity is presented and accepted within the new SNC (Central nervous system) classification of OMS in 2000. This is about a patient with 52 years old with 9 month of evolution history who presents signs of weight loss and is hospitalized with HEC progressive elements, hydrocephalusand installled coma. The Computerized Axial Tomography reveals expansive process in the posterior fossa hemispheric and cerebellopontine angle 4x5 cms inhomogeneous with bleeding elements and lipid content areas. Is arises the probability of Epidermoid cyst. The surgery is carried out with complete excision of the encapsulated aspiratable lesion. Good postoperative course without gaps. The histopathology revealed typical elements described in the literature: presence of adipose cells and neurocytic proliferation with small elements.This led that the tumor received among others the adult lipomeduloblastoma name but showing a good prognosis in contrast with the classic medulloblastoma. Currently cataloged such as grade II and there are not statistics in the literature because there are only published isolated cases

  18. Xeroderma pigmentosum. Case presentation.

    Directory of Open Access Journals (Sweden)

    Damaris Díaz Leonard

    2008-08-01

    Full Text Available Twelve years old patient (YGS, female, white, of rural origin; with history of facial and truncal bullae since the age of eight months when exposed to the sun light. It was first diagnosed as solar dermatitis. At the age of 6 it was assessed as xeroderma pigmentosum. This diagnosis was confirmed at the age of 10 by the histopathology department and reassessed by the National Reference Centre. For the infrequency of this disease, a bibliographic revision was carried out to make a report for this case presentation.

  19. Presentation of the Dossier

    Directory of Open Access Journals (Sweden)

    Tércio Machado Siqueira

    2011-06-01

    Full Text Available The Week of Theological Studies (SETET in 2010 had the theme "Bible and daily life: the Word of God in the everyday life of communities of faith." The lectures where guided by the proposal to establish a link between the Bible and the common pastoral practice of local churches. It was a week where one could observe the importance of re-reading the Bible as a critical academic reflection of study allied to the practice of faith.In this sense, as proposed by the Editor of the Revista Caminhando, this edition contains a dossier, whose guiding principle is the theme of the SETET. The articles presented here are the result of the conferences held in the Week. A major highlight is the fact that the lectures were given in order to maintain a dialogue between the Bible, Theology and Ministry.In this journal, the reader will find reflections about worship in a biblical and pastoral perspective. The biblical reflection we ha a number of significant articles for the discussion of the proposed topic: Samuel F. Salgado, biblical scholar, highlights the importance of worship as a meetingplace, and Luiz Carlos Ramos, pastoralist, discusses the origins of preaching as an essential element of worship.The subject of re-reading biblical texts count with texts by Rui de Souza Josgrilberg, systematic theologian, Suely Xavier dos Santos, biblical scholar, and Jonas Machado, biblical scholar, who deal with reading the Bible in the daily life. Josgrilberg highlights the value of the hermeneutical process and daily life to approximate the world of the Bible to our world. Santos explores the biblical perspective of everyday life and the practical implications for today. Machado, in turn, presents the characteristics of Bible reading in a popular perspective and makes some suggestions to avoid dangerous interpretations.The biblical scholars, Tercio Machado Siqueira and Marcelo Carneiro,as Josué Lazier, educator, present the reading of the Bible related to education

  20. Present on Site

    DEFF Research Database (Denmark)

    Ingemann, Bruno

    Why are exhibitions and museums so important? What can they be used for? Who determines relevance in a transformative process? Transforming exhibitions is not just something you do, it is something that gets better the more you do it. This book looks at the intersection of the visitor or user, wh...... • Invisibles – The exhibition design processes • Openings – Category, objects and communication Present on site is relevant not only for students and researchers in the field of museum communication, media and design studies, but also for exhibition and museum practitioners....

  1. Exit Presentation -- Maintaining Balance

    Science.gov (United States)

    Heap, Erin

    2010-01-01

    This slide presentation reviews the projects which the author engaged in during an internship at Johnson Space Center. Project 1 was involved with Stochastic Resonance (SR). Stochastic resonance is a phenomenon in which the response of a non-linear system to a weak input signal is optimized by the presence of a particular non-zero level of noise. The goal of this project was to develop a countermeasure for sensorimotor disturbances that are experienced after long duration space flight. The second project was a pilot study that was to examine how adaptation to a novel functional task was affected by postural disturbance.

  2. Craniosynostoses. A case presentation.

    Directory of Open Access Journals (Sweden)

    Barbara Aleida García Hernández

    2008-12-01

    Full Text Available A case of a three-month female infant who was born in an ectopic and institutional delivery is described. His parents are healthy and came to the consultation office due to an enlargement in the posterior part of the head. Precocious Hyperostosis due to synostoses of the sagittal and diastasis suture of the lambdoidal suture was confirmed in the radiography. It was decide to put the patient under surgical treatment after assessing the case with a neurosurgeon. An early diagnosis and treatment of this non frequent disease are of great importance because it does not permit a presentation of neurological sequelae.

  3. Choriocarcinoma presenting with thyrotoxicosis.

    Science.gov (United States)

    Sotello, David; Rivas, Ana Marcella; Test, Victor J; Lado-Abeal, Joaquin

    2016-01-01

    We describe a 26-year-old man with metastatic choriocarcinoma who presented with hyperthyroidism associated with elevated β-human chorionic gonadotropin (B-HCG) and respiratory failure secondary to diffuse lung metastasis. After the first cycle of chemotherapy, the concentration of B-HCG dramatically decreased and the patient became euthyroid, allowing us to discontinue antithyroid medications. The patient's hyperthyroidism was caused by stimulation of the thyroid gland by high B-HCG levels, as shown by the marked improvement of the patient's thyroid function panel after chemotherapy. PMID:26722165

  4. Radwaste - Multimedia presentation

    International Nuclear Information System (INIS)

    Radioactivity is a part of the Nature since the creation of the Earth. We have learned how to use radioactivity in medicine, power industry, and in other areas of life. Similarly as in other activities, waste is generated. We offer you basic information about radioactivity and radioactive waste (radwaste) in four films: Radioactivity, Source of radwaste, Management of radwaste. In the glossary are video presentations: Container (Castor) for radioactive waste; Deep underground repository; Transport vehicle; WWER type reactor. Encyclopedic part of the program contains detailed theoretical and practical information about use of radioactivity and radioactive waste. You will find the explanation in the part Glossary. (authors)

  5. Toxocariasis Presenting as Encephalomyelitis

    Directory of Open Access Journals (Sweden)

    Gregory Helsen

    2011-01-01

    Full Text Available We describe a farmer who presented with a clinical picture of a transverse thoracic myelitis. MRI showed inflammatory lesions in brain and thoracic spinal cord. Toxocariasis was suspected because of eosinophilia in blood and cerebrospinal fluid, and this diagnosis was confirmed immunologically. He was successfully treated with antihelminthics in combination with corticosteroids. Neurotoxocariasis is rare and diagnosis can be difficult because of the different and atypical clinical manifestations. It should be considered in every case of central neurological syndrome associated with eosinophilia.

  6. Radiological presentation of neurosarcoidosis

    Directory of Open Access Journals (Sweden)

    Stjepanović Mihailo I.

    2014-01-01

    Full Text Available Introduction. In diagnostics of neurosarcoidosis, radiological diagnostic procedures are available, non-invasive and they contribute significantly to the diagnosis of this disease. The aim of this paper is to present a brief overview of the radiological diagnostic methods, their application, and their importance in daily clinical work with these patients. Radiological Presentation of Neurosarcoidosis. Magnetic resonance is the method of choice in diagnostics of this disease. Computed tomography can also be helpful in patients with contraindications for magnetic resonance, although it is less precise in assessing the involvement of the periventricular white matter, hypothalamus, and cranial nerves. The number of lesions and the degree of involvement of the parenchyma and leptomeninges are better seen by magnetic resonance than by computed tomography scan. It is important to note that the magnetic resonance imaging may be normal in patients with neurosarcoidosis, especially in patients with cranial neuropathy, or in patients treated with corticosteroids. There is a number of variability in the occurrence of neurosarcoidosis on radiological images. Conclusion. Radiological procedures are on the very top of diagnostic pyramid of this disease due to their availability, non-invasiveness, and precision.

  7. Bad (Re)Presentations

    CERN Multimedia

    Computer Security Team

    2013-01-01

    This time, we would like to address copyright violations (again) - but with a twist. While previous articles focussed on “Music, videos and the risk for CERN” or on software licences, the focus is now on using photos, music and images “found” on the Web for presentations, publications and web pages…   Just recently, a video produced for CERN and published on YouTube and Facebook used background music from a contemporary popular artist. However, the people responsible failed to obtain the appropriate permission to actually use that music. They thought that having bought it on iTunes was sufficient. But it was not: “buying” means you have the right to listen, but not the right for further distribution or re-publication. As a result, the videos were pulled from YouTube and Facebook. Similarly, how many of us integrate graphics and images “found” on the Web into our presentations?  How many of us...

  8. DOE financial assurance presentation

    International Nuclear Information System (INIS)

    The presentation topic is California's approach to license application review in meeting financial assurances for the proposed Ward Valley site. The purpose of the presentation is to provide information on specific financial assurance provisions contained in 10 CFR Part 61 and how California intends to satisfy those requirements. Also, as rate setter, California intends to demonstrate how it will assure allowable costs to the rate base though a financial prudency review. The key provisions of financial assurance are: 10 CFR Section 61.61 - This provision requires an applicant to demonstrate its ability to finance licensed activities; 10 CFR Section 61.62 - This provision requires an applicant to provide assurance that sufficient funds will be available for site closure and stabilization; and 10 CFR Section 61.63 - This provision requires an applicant to provide 'a copy of a binding arrangement, such as a lease, between the applicant and the disposal site owner, so that sufficient funds will be available to cover the costs of the institutional control period.' To assist California in its determination of financial assurance compliance to be demonstrated by the applicant for Part 61 requirements, is NUREG guidance document 1199 'Standard Format and Content of a License Application for a Low-Level Radioactive Waste (LLRW) Disposal Facility.' The detailed financial assurance provisions of NUREG 1199 are then embodied in NUREG 1200, 'Standard Review Plant for the Review of a License Application for a LLRW Disposal Facility.'

  9. EDITORIAL: Presentation of Manuscripts

    Science.gov (United States)

    Hudson, R. P.

    1984-01-01

    We wish to draw the attention of authors to two points concerning the presentation of manuscripts. First, some changes have been made recently in our Instructions to Authors. We have reduced from two to one the number of duplicate copies of the manuscript required, asked for corrected proofs to be returned to the Editor rather than directly to the publishers, clarified that a single set of illustration-photographs will suffice, removed a specific suggestion for a style manual that we had offered for general guidance only, and added an instruction on conventions in spelling and hyphenation. Secondly, authors are required, of course, to present a thorough analysis of their experimental data and to include an estimate of their uncertainty. For this purpose, however, we strongly encourage the authors to follow the recommendations put forward by an international working group [1] to the Comité International des Poids et Mesures (CIPM) and endorsed by that body in its Recommandation 1 (CI-1981). This recommendation has been published by the CIPM [2] and was also summarized recently in this journal [3]. [1] 1981 Metrologia 17 69-74, in particular, see pp 73-74 [2] 1981 ProcA~¨s-Verbaux CIPM 10th Session 49, A1 A12. An English language version is available on application to the Director of the Bureau International des Poids et Mesures. [3] 1982 Metrologia 18 41-44, in particular, see p 44.

  10. Presenting numerical risk estimates

    International Nuclear Information System (INIS)

    The Environment Agency for England and Wales has, together with the other Environment Agencies, published guidance on the requirements for authorisation for the disposal of low-level and intermediate-level radioactive waste. The guidance specifies an individual risk target for the post-closure period, and requires developers to consider collective radiological impacts. Information on how risks and impacts should be calculated or assessed has not been published. The objectives of this report are to provide background information on the calculation of risk, to review how regulatory regimes for other activities and in other countries use risk criteria, including both individual and societal risk criteria. Conclusions and recommendations are presented on how the Environment Agency might develop additional guidance to ensure that safety cases meet the Agency's requirements

  11. ANDRAD - Present and future

    International Nuclear Information System (INIS)

    Full text: Binding responsibility for the radioactive waste, until it has decayed - that is the aim for which the Romanian Government has created ANDRAD, the National Agency for Radioactive Waste. By the establishment of this organization, Romania meets the requirements of the 'Joint Convention on Safety of Spent Nuclear Fuel Management and Safety of Radioactive Waste Management' and of the 'European Council Conclusions on Nuclear Safety'. The main objective of ANDRAD is the safe management of spent nuclear fuel and radioactive waste, including disposal, under conditions that ensure the nuclear security and the protection against ionizing radiations of the staff professionally exposed, of the population, environment and property, at present and in the future, without compromising the needs of the next generations. (authors)

  12. Film Presentation: Die Urknallmaschine

    CERN Multimedia

    Carolyn Lee

    2010-01-01

    Die Urknallmaschine, an Austrian film by Gerd Baldauf, narrated by Norbert Frischauf (Alpha Österreich - ORF, 2009).  In CERN’s gigantic complex particles are accelerated to almost the speed of light, brought to collision and made to divide into even smaller particles. Public opinion of CERN’s research is also divided. Sceptics fear that black holes may be created. Might the goal to study the origin of the world lead to its destruction? The Austrian researcher Norbert Frischauf worked at CERN for many years. With his guidance it is possible to explore the world’s largest research centre, get a glimpse of the fascinating work the scientists do there and take a crash course in particle physics. Die Urknallmaschine will be presented on Friday, 25 June from 13:00 to 14:00 in the Main Auditorium. Language: German

  13. RESRAD model presentation

    Energy Technology Data Exchange (ETDEWEB)

    Yu, C.; Faillace, E.; Chen, S.Y. [Argonne National Lab., IL (United States); Wallo, A. III; Williams, W.A.; Peterson, H.; Domotor, S. [Dept. of Energy, Washington, DC (United States)

    1998-05-01

    RESRAD was one of the multimedia models selected by the US Nuclear Regulatory Commission (NRC) to include in its workshop on radiation dose modeling and demonstration of compliance with the radiological criteria for license termination. This paper is a summary of the presentation made at the workshop and focuses on the 10 questions the NRC distributed to all participants prior to the workshop. The code selection criteria, which were solicited by the NRC, for demonstrating compliance with the license termination rule are also included. Among the RESRAD family of codes, RESRAD and RESRAD-BUILD are designed for evaluating radiological contamination in soils and in buildings. Many documents have been published to support the use of these codes. This paper focuses on these two codes. The pathways considered, the databases and parameters used, quality control and quality assurance, benchmarking, verification and validation of these codes, and capabilities as well as limitations of these codes are discussed in detail.

  14. Water Past and Present

    Science.gov (United States)

    2008-01-01

    This image of sulfate and water ice deposits in the Olympia Undae region of Mars was taken by the Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) at 2213 UTC on October 2, 2006 (6:13 p.m. EDT) near 81.6 degrees north latitude, 188.9 degrees east longitude. CRISM's image was taken in 544 colors covering 0.36-3.92 micrometers, and shows features as small as 20 meters (66 feet) across. Olympia Undae is a large dune field that stretches some 1,100 kilometers (684 miles) across the northern polar region of Mars, just south of the ice cap. The region holds a vast expanse of complex, shifting dunes and is best described as a sand sea or erg similar to the Sahara. The two images above provide interesting clues into Mars' history by revealing the planet's wet past and frozen present. The left image is an infrared, false-color image that reveals dark-colored dunes overlying a lighter substrate. Spectral data from CRISM and its sister instrument OMEGA suggest similar compositions of these dunes and the dark basal, or lowermost, unit of the north polar layered deposits. HIRISE images revealed cross-bedding (crossed layers that are oriented at a different angle to the main layer) in this dark unit. On Earth, cross-bedded sediments can form in both windy and watery environments. The dark polar basal unit on Mars is interpreted as a sand sheet underlying and pre-dating the ice, and now being eroded to dunes by the Martian winds. The mineralogy of the Olympia Undae region holds a record of past water. CRISM spectral data (right image) shows that the darker dunes are rich in polyhydrated sulfate (sulfates with more than one water molecule incorporated into each molecule of the mineral). The mineral gypsum is a polyhydrated sulfate, and the most likely constituent in these dunes. The gypsum probably formed by evaporation of ancient, saline water or by aqueous alteration of the silicate portion of the dune material. Areas shaded in red are cover by dust. Blue areas in

  15. Presentation of Pydio

    CERN Document Server

    CERN. Geneva

    2014-01-01

    **Pydio is an open-source platform for file sharing and synchronisation.** It is wildly used by enterprises and organizations worldwide, including major universities. Pydio comes with a rich web-based interface, native clients for both iOS and Android mobile devices, and lately a new sync client for desktop platforms. Pydio v6 is of great useability and introduces many new features that makes it the ultimate sharing machine. Its architecture makes it a perfect fit for either easily deploying an on-premise dropbox solution, or building more complicated solutions where the box feature is integrated as OEM. Storage-agnostic, Pydio is a simple layer that can be deployed on top of any storage backend, thus providing scalability and high-availability out-of-the-box. Charles du Jeu is the lead developer of the solution and will briefly present its feature and how it can fit for research and engineering purpose. See https://pyd.io/ for more information.

  16. Extreme lateral transcondylar approach to the skull base.

    Directory of Open Access Journals (Sweden)

    Banerji D

    1999-01-01

    Full Text Available In this study, the authors present their experience of using extreme later transcondylar approach (ELTC for treating 7 patients with lesions in the anterolateral foramen magnum, upper cervical spine and cerebellopontine angle reaching upto jugular foramen. The tumours included meningiomas, neurofibromas (2 cases each, chondrosarcoma, epidermoid and aneurysmal bone cyst (one case each. The approach was used alone, in combination with retrolabyrinthine presigmoid approach in a patient with lower cranial nerve neurofibroma extending extracranially through the jugular foramen, or in combination with partial C1-C3 laminectomy in two patients with meningiomas situated anterolateral to the cord from the foramen magnum to C3. In two patients with extradural vertebral artery (VA entrapment by a chondrosarcoma and aneurysmal bone cyst respectively, the vertebral artery was ligated distal to the tumour. The tumours were totally excised in five cases and partially in two. There was no preoperative mortality. The major complications included cerebrospinal fluid leak from the wound (3 cases and increase in lower cranial nerve paresis (2 cases. At follow up, ranging from 6 months to 2 years, 5 patients showed no tumour recurrence. There was improvement in neurological status. One patient, with a partially excised aneurysmal bone cyst, showed no added deficits or increase in the tumour size. However, there was a massive regrowth in the patient with chondrosarcoma after 6 months. This technique provided a wide surgical exposure with direct visualization of the tumour-anterior cord interface, early proximal control of the VA and preservation of lower cranial nerves.

  17. TACE Case Presentations

    Directory of Open Access Journals (Sweden)

    Mahyar Mohammadifard

    2010-05-01

    Full Text Available Gold standard treatment of hepatocellular carci-noma is surgical resection but more than 80% of patients with HCC are unresectable at the time of diagnosis, and due to poor local circumstances or the patient's general condition, the prognosis is poor. "nBecause HCC tumors are fed exclusively by the he-patic artery, successful TACE leads to tumor necrosis. The liver parenchyma is rarely damaged because it is fed by the portal vein. Injection of an emulsion of iodized oil and cytostatic agents into the hepatic artery leads to selective deposition of the emulsion in the tumor. Compared with intravenous administration of cytostatic material, TACE reduces the maximum plasma concentration and increases the average concentration of cytostatic agents in the tumor, especially when the cytostatic material is combined with gelatin powder particles. "nFor example, concentration of an emulsion of cisplatin in iodized oil 4-9 weeks after intraarterial administration is 42 times greater in the tumor than in the parenchyma."nTwo cases of HCC are presented which were treated successfully with TACE 20 months ago."nIn the first patient after one session of TACE, tumor markers fell down into normal range and MDCT showed complete necrosis and cystic changes in the mass without residual or recurrent tumor until this time. "nIn the next case tumor markers showed no significant decrease after the first session of TACE and MDCT showed residual tumor which was fed by an accessory arterial branch from SMA. This branch was treated in another session. Two months later, tumor markers fell down and MDCT showed no tumor activity. "nThese patients have been symptom free after the mentioned interventions.

  18. BOUVERET'S SYNDROME (CASE PRESENTATION

    Directory of Open Access Journals (Sweden)

    Dipak

    2014-01-01

    Full Text Available Bouveret's syndrome is defined as gastric outlet obstruction caused by duodenal impaction of a large gallstone which passes into the duodenal bulb through a cholecystogastric or cholecystoduodenal fistula. We describe a case of Bouv eret's Syndrome in an middle aged patient that was successfully treated with resection of distal part of stomach and 1 st part of duodenum by laparotomy. We will also review the literature on this uncommon condition. Biliary enteric fistula is as such a rar e complication and comparatively rare cause of intestinal obstruction. And even if becomes so; generally it lodges in the terminal ileum and rarely in duodenum. Obstructing proximal part of duodenum or distal part of stomach is a curiosity and i.e. Bouvere t’s syndrome. Generally patient presents with nausea, vomiting, haematemesis, abdominal distention or epigastric pain. G.I. bleeding, obstructive jaundice, pancreatitis or duodenal or gastric perforation are rare complications. The treatment is purely surg ical – either enterolithotomy or gastrotomy with associated cholecystectomy with repair of fistula or enterolithotomy with or without second stage cholecystectomy. It is worth to mention here that so far histological findings of Bouveret’s syndrome are no t described in the literature. Even though findings are not that much specific; but presence of foci of abscesses, dense mixed inflammatory exudates in all the coats of distal part of stomach, 1 st part of duodenum and gall bladder along with formation of l ymphoid follicles with prominent germinal centers in muscle coat are definitely mentionable and we feel these may give clue. On gross examination the thickness of stomach wall and duodenal wall are increased and there is narrowing of lumen. If there is sto ne in gall bladder; it may also show thickened out wall due to presence of chronic cholelithiasis with cholecystitis.

  19. Round table presentation

    International Nuclear Information System (INIS)

    Full text: This Round Table deals with the main problems in the operational implementation of radiation safety standards. I will not reiterate previous comments that were made in the other sessions and round tables but I will make a very wide and open presentation in this regard. Since we are discussing problems, I will present this from a general perspective and not just from a national one. So, in my experience problems result from two main causes: problems at the organization level and those due to unsolved or pending technical aspects. The first group concerns organizational problems. In my view, according to my experience, and not only in Argentina, the basic problems are usually related to ineffectual regulatory performance. Second, non-appropriate technical competence in radiation protection and safety matters at all levels; that means at worker, employer and regulatory levels. However, legal competence is a necessary condition but not a sufficient one. The basic point here is knowledge - knowledge and experience - and we can have a very formal and appropriate background of real competence, real instruments, but if we don't have real technical competence the results will not be very satisfactory. Another topic concerns the inadequate discharge of managerial responsibilities at the operational level and following on from this, a weak safety culture and a lack of an effective quality system. The operational implementation of radiation protection standards is often more formalistic than realistic. So in this type of case, for any given country, a commitment at a very high political level is a necessity. The second set of factors associated with such problems are unsolved or pending technical factors and in my view the issue with the complex system of exemption, clearance and action levels, particularly in the case of commodities, is to establish an adequate set of activity concentration levels for specific radionuclides, either natural or artificial, for

  20. Presentation of findings

    International Nuclear Information System (INIS)

    The conference served an important purpose in bringing together and consolidating information on the termination of nuclear practices from around the world, and the Proceedings will therefore represent a very valuable overview of the current situation. I should add, however, that the information presented at the conference was concentrated on the decommissioning of large nuclear facilities. A concerted international effort should be made to obtain a realistic picture of the scope of the decommissioning task to be expected from the many other practices using radioactive material, for example in medical, industrial and research applications. In this regard, one notes that the IAEA is currently compiling information on the magnitude of this problem, and urge it to continue with this work. This should provide a solid basis for an international discussion of actions to begin solving the problem. A great deal of practical decommissioning experience that has been accumulated was presented at the conference.The international community should consider ways to make this information more widely available. The IAEA could contribute to this by means of a Web-based chat room dedicated to decommissioning. One conclusion from the discussion was that the IAEA should ensure that its safety standards on decommissioning are reviewed, improved and updated, and provide more detailed guidance on practical issues. Turning to the main findings from Sessions 2.A - 2.E, six major topics emerged: the importance of early and thorough planning; social issues; funding; waste management issues; long term retention of knowledge; and the removal of regulatory controls. With regard to the issue of early planning for decommissioning, emphasis was placed during the conference on the importance of planning decommissioning thoroughly. Planning should start as early as possible, ideally at the design stage of a facility, as required by the Joint Convention on the Safety of Spent Fuel Management and on

  1. ANDRAD - Present and Prospects

    International Nuclear Information System (INIS)

    ANDRAD is the national authority charged with nation wide coordination of safe management of spent fuel and radioactive waste including their final disposal. The ANDRAD activities aim at protection of population health and environment against the hazard of ionizing radiations both at present and for the future. Hence, the authority has the following competencies: coordinates the process of safe management of spent fuel and radioactive wastes; establishes and ensures administration and physical protection of the national repositories for final disposal of spent fuel and radioactive wastes. To achieve these objectives the authority makes use of processes and methods of managing the spent fuel and radioactive wastes that can guarantee the permissible level of protection of population and environment against ionizing radiations. Thus, by making use of the best available techniques the management will protect the future generation from paying unjustified prices for minimizing radioactive activity, to reduce the amount of spent fuel and associated radioactive wastes. The authority monitors the implementation by the licensees of their commitments for: financing their own activities of collecting, sorting, treating, conditioning, intermediate storing and transportation up to final disposal of the spent fuel; decommissioning of nuclear and radiological units; reporting annually to ANDRAD the amounts of radioactive wastes resulting from their activities; establishing strategies and annual planning (for intermediate and long terms) of the activities preceding the final disposal; financing ANDRAD activities by annual contribution, etc. ANDRAD has the following obligations: establishes the national strategy for safe management of the radioactive wastes in Romania; establishes the annual plans of activity; maintains and updates the national database concerning the amounts and types of wastes and spent fuels produced within nuclear units and facilities; establishes technical

  2. Texts of presentation

    Energy Technology Data Exchange (ETDEWEB)

    Magnin, G.; Vidolov, K.; Dufour-Fallot, B.; Dewarrat, Th.; Rose, T.; Favatier, A.; Gazeley, D.; Pujol, T.; Worner, D.; Van de Wel, E.; Revaz, J.M.; Clerfayt, G.; Creedy, A.; Moisan, F.; Geissler, M.; Isbell, P.; Macaluso, M.; Litzka, V.; Gillis, W.; Jarvis, I.; Gorg, M.; Bebie, B.

    2004-07-01

    Implementing a sustainable local energy policy involves a long term reflection on the general interest, energy efficiency, distributed generation and environmental protection. Providing services on a market involves looking for activities that are profitable, if possible in the 'short-term'. The aim of this conference is to analyse the possibility of reconciling these apparently contradictory requirements and how this can be achieved. This conference brings together the best specialists from European municipalities as well as important partners for local authorities (energy agencies, service companies, institutions, etc.) in order to discuss the public-private partnerships concerning the various functions that municipalities may perform in the energy field as consumers and customers, planners and organizers of urban space and rousers as regards inhabitants and economic players of their areas. This document contains the summaries of the following presentations: 1 - Performance contracting: Bulgarian municipalities use private capital for energy efficiency improvement (K. VIDOLOV, Varna (BG)), Contracting experiences in Swiss municipalities: consistent energy policy thanks to the Energy-city label (B. DUFOUR-FALLOT and T. DEWARRAT (CH)), Experience of contracting in the domestic sector (T. ROSE (GB)); 2 - Public procurement: Multicolor electricity (A. FAVATIER (CH)), Tendering for new green electricity capacity (D. GAZELEY (GB)), The Barcelona solar thermal ordinance (T. PUJOL (ES)); 3 - Urban planning and schemes: Influencing energy issues through urban planning (D. WOERNER (DE)), Tendering for the supply of energy infrastructure (E. VAN DE WEL (NL)), Concessions and public utility warranty (J.M. REVAZ (CH)); 4 - Certificate schemes: the market of green certificates in Wallonia region in a liberalized power market (G. CLERFAYT (BE)), The Carbon Neutral{sup R} project: a voluntary certification scheme with opportunity for implementation in other European

  3. Comparação entre dois métodos de detecção de DNA de papilomavírus humano em carcinoma epidermoide de lábio Comparison between two methods for human papilomavírus DNA detection in lip squamous cell carcinoma

    Directory of Open Access Journals (Sweden)

    Adriana Demathe

    2010-04-01

    Full Text Available Introdução: Recentemente o papilomavírus humano (HPV tem sido associado à carcinogênese oral. A metodologia empregada na detecção do vírus é uma das maiores causas observadas da grande variabilidade nas taxas de detecção do HPV. Objetivo: Este estudo comparou a sensibilidade de detecção do DNA do HPV em casos de carcinoma epidermoide de lábio utilizando a amplificação do DNA viral por reação em cadeia da polimerase (PCR ou nPCR. Material e método: Foram utilizadas 33 amostras provenientes de casos de carcinoma epidermoide de lábio. Para as extrações do DNA utilizou-se o sistema QIAamp DNA Mini Kit. Como controle interno utilizou-se o gene da b-globina. Das 33 amostras iniciais, 30 foram positivas para o gene b-globina, sendo utilizadas para detectar o DNA viral. Comparou-se a amplificação do DNA viral pelos métodos da PCR com os oligonucleotídeos MY09/MY11 e nPCR, empregando-se os pares de oligonucleotídeos iniciadores MY09/MY11 e, na segunda etapa, o par GP5+/GP6+. O controle positivo para a presença do DNA do HPV utilizado foi a linhagem de células HeLa e, como controle negativo, a mistura de amplificação sem DNA. A análise dos produtos de PCR e nPCR para HPV foi realizada por eletroforese em gel de poliacrilamida a 8%. Resultados: Utilizando-se o método da PCR, a amplificação do DNA do HPV foi constatada em dois casos. Com a nPCR foi verificada presença de DNA viral em 13 das 30 amostras. Conclusão: Com a utilização da nPCR, a detecção do HPV nos casos estudados aumentou mais de seis vezes.Introduction: Human papillomavirus (HPV has been currently associated with oral carcinogesis. The methodology applied in virus detection is one of the main reasons for the great variability observed in HPV detection. Objectives: This study compared HPV DNA detection efficiency in lip squamous cell carcinoma samples (SCC using viral DNA amplification by PCR or nPCR. Methods: Thirty three samples of lip squamous cell

  4. Presentation

    OpenAIRE

    Nicanor Lopes

    2010-01-01

    The Journal Caminhando debuts with a new editorial format: eachmagazine will have a Dossier.In 2010 Christianity celebrated the centenary of Edinburgh. TheWorld Missionary Conference in Edinburgh in 1910 is regarded by manyas missiological watershed in the missionary and ecumenical movement.So the Faculty of Theology of the Methodist Church (FATEO) decidedto organize a Wesleyan Week discussing the issue of mission. For anevent of this magnitude FATEO invited the Rev. Dr. Wesley Ariarajah,Meth...

  5. Presentation

    Directory of Open Access Journals (Sweden)

    Tercio Machado Siqueira

    1986-08-01

    Full Text Available This issue of Caminhando contains an article written by Methodist theologian, Dr. John B. Cobb, Jr., of The Claremont School of Theology, California, USA. The publication of this work has many purposes, but the main one is to provide the basic text of the "Meeting of the Process Theology and Liberation Theology" to be held in Sao Paulo, under the coordination of the Faculty of Theology. The attempt to bring together theologians of the "periphery" and the "center" of the world is no longer a pioneer one. In 1977, E. Dussel and J. Pixley organized a meeting that pointed to the need to build more bridges and continue dialogue. Others came, each one revealing truths so far only recognized by the people of the "periphery" of the world.It is very healthy to know that Dr. Cobb recognizes this, and we understand his decision to be involved in this meeting as a sign of "repentance” of process theologians. I met and lived with Dr. Cobb for a little over two years in Claremont. What impresses about him is his commitment to the mission of the Church. When reading his work, we can see in it the result of someone who is serious about the local church. His active participation in his faith community makes me sure that the reader will come into dialogue with someone who is very serious and has an exaggerated love for the church and its mission.Tercio Machado Siqueira EditorThe journal was reedited in 2009.Helmut RendersEditor of the online-edition.

  6. Pathology of the vestibulocochlear nerve

    Energy Technology Data Exchange (ETDEWEB)

    De Foer, Bert [Department of Radiology, Sint-Augustinus Hospital, Oosterveldlaan 24, 2610 Wilrijk (Belgium)], E-mail: bert.defoer@GZA.be; Kenis, Christoph [Department of Radiology, Sint-Augustinus Hospital, Oosterveldlaan 24, 2610 Wilrijk (Belgium)], E-mail: christophkenis@hotmail.com; Van Melkebeke, Deborah [Department of Neurology, Sint-Augustinus Hospital, Oosterveldlaan 24, 2610 Wilrijk (Belgium)], E-mail: Deborah.vanmelkebeke@Ugent.be; Vercruysse, Jean-Philippe [University Department of ENT, Sint-Augustinus Hospital, Oosterveldlaan 24, 2610 Wilrijk (Belgium)], E-mail: jphver@yahoo.com; Somers, Thomas [University Department of ENT, Sint-Augustinus Hospital, Oosterveldlaan 24, 2610 Wilrijk (Belgium)], E-mail: Thomas.somers@GZA.be; Pouillon, Marc [Department of Radiology, Sint-Augustinus Hospital, Oosterveldlaan 24, 2610 Wilrijk (Belgium)], E-mail: marc.pouillon@GZA.be; Offeciers, Erwin [University Department of ENT, Sint-Augustinus Hospital, Oosterveldlaan 24, 2610 Wilrijk (Belgium)], E-mail: Erwin.offeciers@GZA.be; Casselman, Jan W. [Department of Radiology, AZ Sint-Jan AV Hospital, Ruddershove 10, Bruges (Belgium); Consultant Radiologist, Sint-Augustinus Hospital, Oosterveldlaan 24, 2610 Wilrijk (Belgium); Academic Consultent, University of Ghent (Belgium)], E-mail: jan.casselman@azbrugge.be

    2010-05-15

    There is a large scala of pathology affecting the vestibulocochlear nerve. Magnetic resonance imaging is the method of choice for the investigation of pathology of the vestibulocochlear nerve. Congenital pathology mainly consists of agenesis or hypoplasia of the vestibulocochlear nerve. Tumoral pathology affecting the vestibulocochlear nerve is most frequently located in the internal auditory canal or cerebellopontine angle. Schwannoma of the vestibulocochlear nerve is the most frequently found tumoral lesion followed by meningeoma, arachnoid cyst and epidermoid cyst. The most frequently encountered pathologies as well as some more rare entities are discussed in this chapter.

  7. Mathematical Reasoning in Teachers' Presentations

    Science.gov (United States)

    Bergqvist, Tomas; Lithner, Johan

    2012-01-01

    This paper presents a study of the opportunities presented to students that allow them to learn different types of mathematical reasoning during teachers' ordinary task solving presentations. The characteristics of algorithmic and creative reasoning that are seen in the presentations are analyzed. We find that most task solutions are based on…

  8. METHODS FOR PERFECTING PRESENTATION SKILLS

    OpenAIRE

    Daniela N. Ilieva - Koleva

    2014-01-01

    Presentation skills are crucial for the nowadays managers and business people. This article aims to examine different traditional and unconventional methods for enhancing and perfecting presentation skills. It provides suggestions on how to structure a presentation, what type of verbal language to include, and pays significant attention to body language during presentations, as well as to the relation between the presenter and the audience. The paper highlights a variety of instruments and te...

  9. Put Power into Your Presentations: Using Presentation Software Effectively

    Science.gov (United States)

    Safransky, Robert J.; Burmeister, Marsha L.

    2009-01-01

    Microsoft PowerPoint, Apple Keynote, and OpenOffice Impress are relatively common tools in the classroom and in the boardroom these days. What makes presentation software so popular? As the Chinese proverb declares, a picture is worth a thousand words. People like visual presentations. Presentation software can make even a dull subject come to…

  10. Analysis of the role of the gene coding the Amyloid-Precursor Protein Binding Protein 1 (APP-BP1) in the radio-sensitivity of epidermoid carcinomas of the upper aero-digestive tract infected by the human papillomavirus

    International Nuclear Information System (INIS)

    As the human papillomavirus (HPV) is at the origin of 25% of upper aero-digestive tract cancers, and as these tumours present an increased radio-sensitivity compared to other tumours, probably due to a greater transcriptional activity of p53, the authors report the study on the influence of a decrease of the expression of the APP-BP1 in these tumours which could favour a radio-induced apoptosis. By using a reverse transcriptase polymerase chain reaction (RT-PCR), they assessed the APP-BP1 expression levels as well as expression levels of transcriptions coding onco-proteins known to be over-expressed in HPV+ tumours. They compared the radio-sensitivities of HPV+ and HPV- cells, the first one appearing to be greater than the second one. Short communication

  11. Presentation-Oriented Visualization Techniques.

    Science.gov (United States)

    Kosara, Robert

    2016-01-01

    Data visualization research focuses on data exploration and analysis, yet the vast majority of visualizations people see were created for a different purpose: presentation. Whether we are talking about charts showing data to help make a presenter's point, data visuals created to accompany a news story, or the ubiquitous infographics, many more people consume charts than make them. Traditional visualization techniques treat presentation as an afterthought, but are there techniques uniquely suited to data presentation but not necessarily ideal for exploration and analysis? This article focuses on presentation-oriented techniques, considering their usefulness for presentation first and any other purposes as secondary. PMID:26780762

  12. Present market for nuclear energy

    International Nuclear Information System (INIS)

    The present market for nuclear energy is present since nuclear production and electric power generation to the utilization of radioisotopes in medicine and biology. Some data about the main world suppliers to this market are shown. (E.G.)

  13. Insulinoma presenting as postprandial hypoglycaemia

    OpenAIRE

    Madathil, Asgar; Weaver, Jola

    2011-01-01

    Although insulinoma commonly presents as fasting hypoglycaemia it can rarely present as postprandial hypoglycaemia. We describe a case of insulinoma presenting as postprandial hypoglycaemia and type 2 diabetes mellitus (T2DM). A 60-year-old man presented with a 6 year history of postprandial hypoglycaemic symptoms. A diagnosis of T2DM was made using a standard oral glucose tolerance test to which patient’s postprandial hypoglycaemia was attributed. He was given dietetic advice for postprandia...

  14. Analysis of the role of the gene coding the Amyloid-Precursor Protein Binding Protein 1 (APP-BP1) in the radio-sensitivity of epidermoid carcinomas of the upper aero-digestive tract infected by the human papillomavirus; Analyse du role du gene codant l'Amyloid-Precursor Protein Binding Protein 1 (APP-BP1) dans la radiosensibilite des carcinomes epidermoides des voies aero-digestives superieures infectees par le papillomavirus humain

    Energy Technology Data Exchange (ETDEWEB)

    Guihard, S.; Altmeyer, A.; Ramolu, L.; Macabre, C.; Abecassis, J.; Noel, G.; Jung, A.C. [Centre de lutte contre le cancer Paul-Strauss, 67 - Strasbourg (France)

    2010-10-15

    As the human papillomavirus (HPV) is at the origin of 25% of upper aero-digestive tract cancers, and as these tumours present an increased radio-sensitivity compared to other tumours, probably due to a greater transcriptional activity of p53, the authors report the study on the influence of a decrease of the expression of the APP-BP1 in these tumours which could favour a radio-induced apoptosis. By using a reverse transcriptase polymerase chain reaction (RT-PCR), they assessed the APP-BP1 expression levels as well as expression levels of transcriptions coding onco-proteins known to be over-expressed in HPV+ tumours. They compared the radio-sensitivities of HPV+ and HPV- cells, the first one appearing to be greater than the second one. Short communication

  15. Isolated Torticollis May Present as an Atypical Presentation of Meningitis

    Directory of Open Access Journals (Sweden)

    Roger Chirurgi

    2012-01-01

    Full Text Available Background. Bacterial meningitis is a life-threatening medical emergency that requires urgent diagnosis and treatment. Diagnosis is infrequently missed if the patient presents with the classic symptoms of fever, headache, rash, nuchal rigidity, or Kernig or Brudzinski sign. However, it may be less obvious in neonates, elderly, or immunocompromised patients. Meningitis which presents as isolated torticollis, without any other signs or symptoms, is exceedingly rare. Objective. To identify an abnormal presentation of meningitis in an adult immunocompromised patient. Case Report. We present a case of an adult diabetic male who presented multiple times to the ED with complaint of isolated torticollis, who ultimately was diagnosed with bacterial meningitis. Conclusion. We propose that in the absence of sufficient explanation for acute painful torticollis in an immunocompromised adult patient, further evaluation, possibly including a lumbar puncture may be warranted.

  16. Unusual presentation of Klinefelter syndrome

    Directory of Open Access Journals (Sweden)

    Chanchal Das

    2013-01-01

    Full Text Available Introduction: Klinefelter syndrome usually presents in the puberty and adulthood with its characteristic features. We report a boy who had Klinefelter syndrome with hypospadias and hydrocele. Case Note: Six and half year old boy had complaints of genitourinary problem in the form of hypospadias, small phallus and hydrocele. Karyotyping showed 47,XXY. Conclusion: This case illustrates that Klinefelter syndrome was presented in the infancy with hypospadias and hydrocele which are very uncommon presentation of the disease

  17. Emphysematous pyelonephritis: a rare presentation.

    Directory of Open Access Journals (Sweden)

    Jain S

    2000-01-01

    Full Text Available Emphysematous pyelonephritis is a rare life threatening infection in diabetes characterised by suppurative infection of renal parenchyma and perirenal tissues. It usually presents with fever, nausea, vomiting, abdominal pain, shock, lethargy, and confusion. Diabetic ketoacidosis is an uncommon presentation. In the present case, an elderly female presented with abdominal pain, fever, vomiting, and altered sensorium. She was diagnosed to have diabetic ketoacidosis with metabolic encephalopathy with right emphysematous pyelonephritis. She had an excellent response to medical treatment alone and was later discharged on oral hypoglycaemic agents.

  18. MHC Class Ⅰ Antigen Presentation- Recently Trimmed and Well Presented

    Institute of Scientific and Technical Information of China (English)

    Barry Flutter; Bin Gao

    2004-01-01

    Presentation of antigenic peptide to T cells by major histocompatibility complex (MHC) class Ⅰ molecules is the key to the cellular immune response. Non-self intracellular proteins are processed into short peptides and transported into endoplasmic reticulum (ER) where they are assembled with class Ⅰ molecules assisted by several chaperone proteins to form trimeric complex. MHC class Ⅰ complex loaded with optimised peptides travels to the cell surface of antigen presentation cells to be recognised by T cells. The cells presenting non-self peptides are cleared by CD8 positive T cells. In order to ensure that T cells detect an infection or mutation within the target cells the process of peptide loading and class Ⅰ expression must be carefully regulated. Many of the cellular components involved in antigen processing and class Ⅰ presentation are known and their various functions are now becoming clearer. Cellular & Molecular Immunology. 2004;1(1):22-30.

  19. MHC Class I Antigen Presentation- Recently Trimmed and Well Presented

    Institute of Scientific and Technical Information of China (English)

    BarryFlutter; BinGao

    2004-01-01

    Presentation of antigenic peptide to T cells by major histocompatibility complex (MHC) class I molecules is the key to the cellular immune response. Non-self intracellular proteins are processed into short peptides and transported into endoplasmic reticulum (ER) where they are assembled with class I molecules assisted by several chaperone proteins to form trimeric complex. MHC class I complex loaded with optimised peptides travels to the cell surface of antigen presentation cells to be recognised by T cells. The cells presenting non-self peptides are cleared by CD8 positive T cells. In order to ensure that T cells detect an infection or mutation within the target cells the process of peptide loading and class I expression must be carefully regulated. Many of the cellular components involved in antigen processing and class I presentation are known and their various functions are now becoming clearer. Cellular & Molecular Immunology. 2004;1(1):22-30.

  20. Sternal Tuberculosis: An Uncommon Presentation

    OpenAIRE

    Manish Narang; Archana Dwivedi; Shiva Narang; Gopesh Mehrotra

    2011-01-01

    Primary tubercular osteomyelitis of sternum presenting as an acute swelling over chest is an extremely rare presentation in pediatric population. We herein report such a case which was diagnosed by CT scan showing lytic lesion and aspiration revealed positive culture for Mycobacterium tuberculosis. Child improved with antitubercular treatment.

  1. Sternal Tuberculosis: An Uncommon Presentation

    Directory of Open Access Journals (Sweden)

    Manish Narang

    2011-12-01

    Full Text Available Primary tubercular osteomyelitis of sternum presenting as an acute swelling over chest is an extremely rare presentation in pediatric population. We herein report such a case which was diagnosed by CT scan showing lytic lesion and aspiration revealed positive culture for Mycobacterium tuberculosis. Child improved with antitubercular treatment.

  2. Present status of processing method

    Energy Technology Data Exchange (ETDEWEB)

    Kosako, Kazuaki [Sumitomo Atomic Energy Industries Ltd., Tokyo (Japan)

    1998-11-01

    Present status of processing method for a high-energy nuclear data file was examined. The NJOY94 code is the only one available to the processing. In Japan, present processing used NJOY94 is orienting toward the production of traditional cross section library, because a high-energy transport code using a high-energy cross section library is indistinct. (author)

  3. Integrating Financial Analysis into Presentations

    Science.gov (United States)

    Saatci, Elizabeth

    2004-01-01

    Assignments that combine case studies with applied research can work for presentations as well as for written reports. One such assignment that has proven to be successful both in the author's classes and later in the students' professional lives is based on (1) incorporating banking concepts and encouraging their use in presentations; (2)…

  4. Neutrino astronomy: Present and future

    Indian Academy of Sciences (India)

    Thomas McCauley

    2006-10-01

    I briefly review the present and future status of the burgeoning field of neutrino astronomy. I outline the astrophysics and particle physics goals, design, and performance of the various current and proposed neutrino telescopes. Also described are present results and future expectations.

  5. Presentations of the SINS Symposium

    International Nuclear Information System (INIS)

    The goal of the symposium was presentation of the scientific researches performed at Soltan Institute for Scientific Research (SINS) as well as their far-reaching directions. Symposium was directed to all scientific workers of the SINS, invited specialist as well as to non-specialists. Presentations were performed mainly by young physicists (postgraduates and post-docs)

  6. Postoperative brachytherapy in epidermoid carcinomas of the floor of mouth

    International Nuclear Information System (INIS)

    Purpose : To analyse the interest of postoperative brachytherapy (BT) in a group of patients with a high risk of local relapse (positive or close surgical margins) for squamous cell carcinoma of the floor of mouth (SCCFM). A comparison with postoperative external beam irradiation in a group of patients of medium risk of local relapse (EBI) for SCCFM with free margins is performed to estimate the benefit of BT. Material et methods : From 1979 to 1992, a first group of 32 patients with a SCCFM (12 T1-2, 20 T3-4-X) received an Ir 192 low dose rate BT using plastic tubes (+EBI for 20 patients) after surgery with positive or close margins. BT was performed in 1 or 2 plans along the surgical scar. When the tongue or the remaining floor where sutured to the internal face of the inferior lip or of the buccal mucosa, a 'bridge technique' was used. The mean dose of BT was 57 Gy (range : 50 - 60) for exclusive BT and 22 Gy (range 15 - 30) when used as a boost (mean EBI dose 50 Gy). During the same time a second group of 36 patients (12 T1-2, 24 T3 - 4 - X) with SCCFM with free surgical margins received a exclusive postoperative EBI (mean dose in the surgical scar was 50 Gy). Excluding the postoperative margin, these 2 groups were comparable for other prognostic factors (tumoral size, node status, age, sex and type of surgery). Results : The mean follow up was 46 months (range : 5 - 145). For BT and EBI groups, the 5-year results (Kaplan-Meier) were respectively : overall survival 62% and 43%, specific survival 74% and 53%, local control 81% and 60% (p = 0.09) (Log Rank) and severe complications (4(32)) and (1(36)). Conclusion : Postoperative BT achieves a good local control for patients with close or positive margins by increasing the dose to the surgical scar with a good tolerance. Given these good results, we confirm this indication for these patients

  7. Giant epidermoid inclusion cyst of the clitoris mimicking clitoromegaly.

    Science.gov (United States)

    Al-Ojaimi, Eftekhar Hassan; Abdulla, Maryam Mohd

    2013-01-01

    We describe a rare case of clitoromegaly due to a large clitoral cyst that occurred spontaneously without any declared previous female genital mutilation. The cyst was excised successfully with good cosmetic results. PMID:23222050

  8. The nature of the present

    CERN Document Server

    Romero, Gustavo E

    2012-01-01

    The feeling of a moving present or `now' seems to form part of our most basic perceptions about reality. Such a present, however, is not reflected in any of our theories of the physical world. In this short note I argue for a tenseless view of time, where what we call `the present' is just an emergent secondary quality arising from the interaction of perceiving self-conscious individuals with their environment. I maintain that there is no flow of time, but just an ordered system of events.

  9. Extradural lipomatosis presenting with paraplegia.

    Directory of Open Access Journals (Sweden)

    Deogaonkar M

    1995-07-01

    Full Text Available An unusual case with spinal extradural lipomatosis in a non-obese and otherwise healthy man is reported. The patient presented with a history of weakness of legs which progressed to paraplegia over a 40 day period.

  10. Gearbox Reliability Collaborative Update (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Sheng, S.

    2013-10-01

    This presentation was given at the Sandia Reliability Workshop in August 2013 and provides information on current statistics, a status update, next steps, and other reliability research and development activities related to the Gearbox Reliability Collaborative.

  11. A centralized audio presentation manager

    Energy Technology Data Exchange (ETDEWEB)

    Papp, A.L. III; Blattner, M.M.

    1994-05-16

    The centralized audio presentation manager addresses the problems which occur when multiple programs running simultaneously attempt to use the audio output of a computer system. Time dependence of sound means that certain auditory messages must be scheduled simultaneously, which can lead to perceptual problems due to psychoacoustic phenomena. Furthermore, the combination of speech and nonspeech audio is examined; each presents its own problems of perceptibility in an acoustic environment composed of multiple auditory streams. The centralized audio presentation manager receives abstract parameterized message requests from the currently running programs, and attempts to create and present a sonic representation in the most perceptible manner through the use of a theoretically and empirically designed rule set.

  12. HYDROGEOLOGIC CASE STUDIES (DENVER PRESENTATION)

    Science.gov (United States)

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  13. Childhood Exposure Factors [Presentation 2015

    Science.gov (United States)

    This is a presentation to be delivered at the Children's Health Protection Advisory Committee Meeting to inform them about the type of data included in the EFH and how it is used in EPA's decision making.

  14. QCD machines - present and future

    International Nuclear Information System (INIS)

    The present status of the currently working and nearly working dedicated QCD machines is reviewed and proposals for future machines are discussed with particular emphasis on the QCD Teraflop Project in the US. (orig.)

  15. Wind Technologies & Evolving Opportunities (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Robichaud, R.

    2014-07-01

    This presentation covers opportunities for wind technology; wind energy market trends; an overview of the National Wind Technology Center near Boulder, Colorado; wind energy price and cost trends; wind turbine technology improvements; and wind resource characterization improvements.

  16. BioFuels Atlas (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Moriarty, K.

    2011-02-01

    Presentation for biennial merit review of Biofuels Atlas, a first-pass visualization tool that allows users to explore the potential of biomass-to-biofuels conversions at various locations and scales.

  17. ECRIS 2010 - Proceedings and Presentations

    International Nuclear Information System (INIS)

    The workshop focussed on the latest developments in performance, modeling and applications of ECR ion sources along with the associated physics and technologies, including plasma physics, beam optics, beam diagnostics, magnet technology.... The presentations were organized around 8 topics: 1) status of ECRIS operation, 2) new developments, 3) ion beams and low energy beam transport (LEBT), 4) pulsed operation, 5) applications, and 6) plasma and beam investigations. Most papers are accompanied with the slides of their presentation

  18. Presenting and Evaluating Qualitative Research

    OpenAIRE

    Anderson, Claire

    2010-01-01

    The purpose of this paper is to help authors to think about ways to present qualitative research papers in the American Journal of Pharmaceutical Education. It also discusses methods for reviewers to assess the rigour, quality, and usefulness of qualitative research. Examples of different ways to present data from interviews, observations, and focus groups are included. The paper concludes with guidance for publishing qualitative research and a checklist for authors and reviewers.

  19. A rare presentation of hypothyroidism

    Directory of Open Access Journals (Sweden)

    Betsy Mathew

    2014-02-01

    Full Text Available In this case report, we have brought out a very rare presentation of hypothyroidism in the form of cataplexy and this case is of significance because there have been no similar case reports of hypothyroidism presenting as cataplexy so far. The other highlight of the case is that treatment of hypothyroidism alone resulted in complete freedom from cataplexy without the need for agrypnotic drugs. [Int J Res Med Sci 2014; 2(1.000: 328-329

  20. Amebiasis presenting as acute appendicitis.

    Science.gov (United States)

    Andrade, Javier E; Mederos, Raul; Rivero, Haidy; Sendzischew, Morgan A; Soaita, Mauela; Robinson, Morton J; Sendzischew, Harry; Danielpour, Payman

    2007-11-01

    Amebiasis presenting as acute appendicitis is extremely rare. The case of a 38-year-old Hispanic man who presented to the hospital with symptoms and signs suggestive of acute appendicitis is reported. He underwent laparoscopic appendectomy and the pathologic examination of the appendix revealed multiple trophozoites of Entamoeba histolytica. The patient was treated postoperatively with metronidazole for amebiasis, and follow-up stool studies showed no sign of residual infection. The patient has remained asymptomatic. PMID:17984748

  1. Unusual presentation of cutaneous leiomyoma

    Directory of Open Access Journals (Sweden)

    Sapnashree Bhaskar

    2014-01-01

    Full Text Available Herein, we report a case of leiomyoma cutis because of its rarity and unusual presentation. The case presented with a solitary leiomyoma lesion which was painless. However, the adjacent normal appearing area was tender. A biopsy of the lesion as well as of a portion of the adjacent normal appearing area was taken, which confirmed the diagnosis of cutaneous leiomyoma. This may suggest the dormant nature of the disease which has not yet become apparent.

  2. Presentations of the SINS Symposium

    International Nuclear Information System (INIS)

    The goal of the symposium was presentation of the scientific researches performed at Soltan Institute for Scientific Research (SINS) as well as their far-reaching directions. Symposium was directed to all scientific workers of the SINS, invited specialist as well as to non-specialists. Presentations were performed mainly by young physicists (postgraduates and post-docs). In Symposium took part over 100 persons

  3. Leptospirosis presenting as honeymoon fever

    OpenAIRE

    B. de Sainte Marie; M. Delord; G. Dubourg; Gautret, P; Parola, P; Brouqui, P; Lagier, J.C.

    2015-01-01

    An increasing number of travelers from western countries visit tropical regions, questioning western physicians on the prophylaxis, the diagnosis and the therapeutic management of patients with travel-associated infection. In July 2014, a French couple stayed for an adventure-travel in Columbia without malaria prophylaxis. A week after their return the woman presented with fever, myalgia, and retro-orbital pain. Three days later, her husband presented similar symptoms. In both patients, te...

  4. Presentation of the ASTRAL software; Presentation du logiciel ASTRAL

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    This report presents the ASTRAL software (ASTRAL means technical assistance in post-accidental radioprotection) which is aimed to be used as an aid-to-decision tool in the case of an important release of radionuclides in the environment by assessing radionuclide concentration in different environments and food products, determining the potential exposure to irradiation of concerned populations, foreseeing the evolution of the situation, and proposing different scenarios for the management of contaminated areas. The report describes the software general operation, presents the calculation module (main functionalities, concentration index calculation, dose calculation or radiological impact calculation, how countermeasures are taken into account), the data bases (contextual data, data for radio-ecological calculations and for radiological calculations), the software ergonomics (general principles, result selection and display, result printing and input data). Its briefly evokes the development quality assurance, and describes the software implementation architecture

  5. Polycythemia vera presenting as acute myocardial infarction: An unusual presentation

    OpenAIRE

    Bahbahani, Hussain; Aljenaee, Khaled; Bella, Abdelhaleem

    2014-01-01

    Acute myocardial infarction (AMI) is usually seen in the setting of atherosclerosis and its associated risk factors. Myocardial infarction in the young poses a particular challenge, as the disease is less likely, due to atherosclerosis. We report the case of a 37-year-old female patient who presented with ST segment elevation anterolateral AMI. The only abnormality on routine blood investigation was raised hemoglobin and hematocrit. After further testing, she was diagnosed according to the Wo...

  6. Tourette syndrome: a psychoeducational presentation.

    Science.gov (United States)

    Lagiewka-Cook, D; Goulet, J L; Wand, R; Shady, G

    1993-06-01

    Tourette Syndrome (TS) is a neurological disorder with onset prior to age 21. The wide range of difficulties associated with TS present significant barriers to both the positive school functioning of students with TS and the ability of their teachers and peers to cope with the sometimes difficult classroom behavior which results from this syndrome. Since TS children with teachers knowledgeable about TS and its effects on learning fare better than those whose teachers are not knowledgeable, dissemination of this information to school personnel is crucial. Health teaching is a significant contribution within the nursing role. In order to ameliorate some of the stressors and academic problems experienced by children and adolescents with TS, the TS Clinic of St. Boniface General Hospital is composed of a multidisciplinary team whose mandate includes the provision of educational awareness audiovisual presentations to schools and the general community throughout Manitoba. This presentation will include the historical, psychosocial, educational, symptomatological, and treatment aspects of TS. PMID:8274388

  7. Dexmedetomidine overdosage: An unusual presentation

    Directory of Open Access Journals (Sweden)

    Soumya S Nath

    2013-01-01

    Full Text Available We present a case of dexmedetomidine toxicity in a 3-year-old child. The case report describes the features and outlines the treatment strategy adopted. The child presented with bradypnoea, bradycardia, hypotension, deep hypnosis and miosis. He was successfully managed with oxygen, saline boluses and adrenaline infusion. He became haemodynamically stable with adrenaline infusion. He started responding to painful stimuli in 3 h and became oriented in 7 h. Dexmedetomidine, a selective α2 adrenoceptor agonist, is claimed to have a wide safety margin. This case report highlights the fact that dexmedetomidine administered in a toxic dose may be life-threatening may present with miosis and adrenaline infusion may be a useful supportive treatment.

  8. Thick Presentism and Newtonian Mechanics

    CERN Document Server

    Lubashevsky, Ihor

    2016-01-01

    In the present paper I argue that the formalism of Newtonian mechanics stems directly from the general principle to be called the principle of microlevel reducibility which physical systems obey in the realm of classical physics. This principle assumes, first, that all the properties of physical systems must be determined by their states at the current moment of time, in a slogan form it is "only the present matters to physics." Second, it postulates that any physical system is nothing but an ensemble of structureless particles arranged in some whose interaction obeys the superposition principle. I substantiate this statement and demonstrate directly how the formalism of differential equations, the notion of forces in Newtonian mechanics, the concept of phase space and initial conditions, the principle of least actions, etc. result from the principle of microlevel reducibility. The philosophical concept of thick presentism and the introduction of two dimensional time---physical time and meta-time that are mut...

  9. Neonatal hemophilia: a rare presentation

    Directory of Open Access Journals (Sweden)

    Nuno Ferreira

    2015-12-01

    Full Text Available Hemophilia A is a X-linked hereditary condition that lead to decreased factor VIII activity, occurs mainly in males. Decreased factor VIII activity leads to increased risk of bleeding events. During neonatal period, diagnosis is made after post-partum bleeding complication or unexpected bleeding after medical procedures. Subgaleal hemorrhage during neonatal period is a rare, severe extracranial bleeding with high mortality and usually related to traumatic labor or coagulation disorders. Subgaleal hemorrhage complications result from massive bleeding. We present a neonate with unremarkable family history and uneventful pregnancy with a vaginal delivery with no instrumentation, presenting with severe subgaleal bleeding at 52 hours of life. Aggressive support measures were implemented and bleeding managed. The unexpected bleeding lead to a coagulation study and the diagnosis of severe hemophilia A. There were no known sequelae. This case shows a rare hemophilia presentation reflecting the importance of coagulation studies when faced with unexplained severe bleeding.

  10. Comprehensible Presentation of Topological Information

    Energy Technology Data Exchange (ETDEWEB)

    Weber, Gunther H. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Beketayev, Kenes [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Bremer, Peer-Timo [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Hamann, Bernd [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Haranczyk, Maciej [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Hlawitschka, Mario [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Pascucci, Valerio [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2012-03-05

    Topological information has proven very valuable in the analysis of scientific data. An important challenge that remains is presenting this highly abstract information in a way that it is comprehensible even if one does not have an in-depth background in topology. Furthermore, it is often desirable to combine the structural insight gained by topological analysis with complementary information, such as geometric information. We present an overview over methods that use metaphors to make topological information more accessible to non-expert users, and we demonstrate their applicability to a range of scientific data sets. With the increasingly complex output of exascale simulations, the importance of having effective means of providing a comprehensible, abstract overview over data will grow. The techniques that we present will serve as an important foundation for this purpose.

  11. Double beta decay: present status

    OpenAIRE

    Barabash, A. S.

    2008-01-01

    The present status of double beta decay experiments (including the search for $2\\beta^{+}$, EC$\\beta^{+}$ and ECEC processes) are reviewed. The results of the most sensitive experiments are discussed. Average and recommended half-life values for two-neutrino double beta decay are presented. Conservative upper limits on effective Majorana neutrino mass and the coupling constant of the Majoron to the neutrino are established as $ < 0.75$ eV and $ < 1.9 \\cdot 10^{-4}$, respectively. Proposals fo...

  12. Technical presentation: Next Generation Oscilloscopes

    CERN Multimedia

    PH Department

    2011-01-01

      Rohde & Schwarz "Next Generation Oscilloscopes" - Introduction and Presentation Agenda: Wednesday 23 March  -  09:30 to 11:30 (open end) Bldg. 13-2-005 Language: English 09.30 Presentation "Next Generation Oscilloscopes" from Rohde & Schwarz RTO / RTM in theory and practice Gerard Walker 10.15 Technical design details from R&D Dr. Markus Freidhof 10.45 Scope and Probe Roadmap (confidential) Guido Schulze 11.00 Open Discussion Feedback, first impression, wishes, needs and requirements from CERN All 11.30 Expert Talks, Hands on All Mr. Dr. Markus Freidhof, Head of R&D Oscilloscopes, Rohde & Schwarz, Germany; Mr. Guido Schulze, ...

  13. Medical resources presentation on WWW

    Directory of Open Access Journals (Sweden)

    Anamarija Rožić-Hristovski

    1997-01-01

    Full Text Available Librarians are confronted with new challanges offered by currently developing information technologies. There are more and more information sources in medicine that comprise bibliographic and textual databases, various books and textbooks. These are available on different computer media. The task of librarians is to introduce scientists, health care professionals and students to digital library and present ali available sources, so that they can choose the proper solution for their information needs. CMK has decided to design a home page to present its services and even more medical information resources accessible locally, on the local network and on the Internet.

  14. Scrub Typhus with Unusual Presentation

    Directory of Open Access Journals (Sweden)

    A.S. Praveen Kumar

    2014-01-01

    Full Text Available Scrub typhus is an acute, febrile zoonosis caused by an obligate intracellular bacterium Orientia tsutsugamushi. The clinical manifestations of the disease range from subclinical to fatal organ failure. The common symptoms are fever, chills, headache, myalgia, dry cough, lymphadenopathy, and gastrointestinal disturbances. The presentation with complications is usually due to delay in diagnosis and treatment. We report three cases of scrub typhus that presented with features of meningo-encephalitis, which is very unusual, and all patients recovered with empirical doxycycline treatment.

  15. Present status of parton distributions

    Energy Technology Data Exchange (ETDEWEB)

    Martin, A.D.; Stirling, W.J. [Durham Univ. (United Kingdom). Dept. of Physics; Roberts, R.G.

    1993-04-01

    We review the present knowledge of the partonic structure of the proton. We compare and contrast the parton distributions obtained recently by two international collaborations in global analyses of deep-inelastic and related data, including new structure function measurements. We discuss the information that is at present available on the flavour asymmetry of the sea quark distributions of the proton and, in particular, describe how well experiments can discriminate between u-bar, d-bar and s-bar. We comment on extrapolations into the small x region that is accessible at HERA (Hadron-Elektron-Ring-Anlage). (author).

  16. Present status of parton distributions

    Energy Technology Data Exchange (ETDEWEB)

    Martin, A.D.; Stirling, W.J. (Durham Univ. (United Kingdom). Dept. of Physics); Roberts, R.G. (Rutherford Appleton Lab., Chilton (United Kingdom))

    1993-10-01

    We review the present knowledge of the partonic structure of the proton. We compare and contrast the parton distributions obtained recently by the MRS and CTEQ collaborations in global analyses of deep-inelastic and related data, including the new NMC and CCFR structure function measurements. We discuss the information that is at present available on the flavour asymmetry of the sea-quark distributions of the proton and, in particular, describe how well experiments can discriminate between u-bar, d-bar and s-bar. We comment on extrapolations into the small-x region that is accessible at HERA. (author).

  17. Present status of parton distributions

    Energy Technology Data Exchange (ETDEWEB)

    Martin, A.D.; Stirling, W.J.; Roberts, R.G.

    1993-04-01

    The authors review the present knowledge of the partonic structure of the proton. They compare and contrast the parton distributions obtained recently by the MRS and CTEQ collaborations in global analyses of deep-inelastic and related data, including the new NMC and CCFR structure function measurements. The authors discuss the information that is at present available on the flavor asymmetry of the sea quark distributions of the proton and, in particular, describe how well experiments can discriminate between u(bar), d(bar) and s(bar). The authors comment on extrapolations into the small x region that is accessible at HERA.

  18. Syntelencephaly presenting with spastic diplegia.

    Science.gov (United States)

    Coleman, L T; McCubbin, J P; Smith, L J; Reddihough, D S; Gardner, R J

    2000-08-01

    Two children with syntelencephaly presented with the predominant clinical picture of spastic diplegia. Brain scanning showed deficient formation of the interhemispheric fissure with fusion of occipital and parietal lobes, and an infolding and protrusion of occipital cortex into the telencephalic ventricle. The fusion extended further posteriorly than the cases of "middle interhemispheric fusion" thus far reported. One 7-year old has poor language development, while the other is regarded, at her present age of 3 years, as being cognitively within the normal range. PMID:11071147

  19. Viewfoils for environmental capabilities presentation

    International Nuclear Information System (INIS)

    This document contains information about the environmental applications of aerial surveys. It discusses the accuracy, dependability, history, advantages, and sensitivity of aerial surveys. Also included, are a brief overview of in-situ gamma spectroscopy and samples of aerial surveys. This document contains entirely of an outline and viewfoils for the presentation

  20. Radiotherapy - past present and future

    International Nuclear Information System (INIS)

    The beginnings of therapeutic applications of x-rays are far less known and surrounded by acrimonious controversy. The past, present and future of radiotherapy are briefly reviewed. The major challenges for hospital physicists is in educating staff members and monitoring the ever broadening use of ionising radiation

  1. GENERALIZED LENTIGINOSIS: AN UNCOMMON PRESENTATION

    Directory of Open Access Journals (Sweden)

    Valluvan

    2014-05-01

    Full Text Available A case of Generalized Lentiginosis is being documented for its rarity. A 27 years old congenitally deaf and mute, presented to our hospital with multiple asymmetrical brown-black to black colored macules involving all over the body sparing mucous membrane of oral cavity, palms and soles with melena. The patient was severely anemic on examination.

  2. DOE Collegiate Wind Competition (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Jones, J.

    2014-02-01

    This presentation for the January Stakeholder Engagement and Outreach webinar outlines the expanded need for workers in the wind industry and provides an overview of the DOE Wind Competition (to be held in May 2014) and the guiding principles of the competition.

  3. Energy consumption: Past, present, future

    Science.gov (United States)

    1973-01-01

    The energy consumption history of the United States and the changes which could occur in consumption characteristics in the next 50 years are presented. The various sources of energy are analyzed to show the limitations involved in development and utilization as a function of time available. Several scenarios were prepared to show the consumption and supply of energy under varying conditions.

  4. PENILE TUBERCULOSIS PRESENTING AS PHIMOSIS

    Directory of Open Access Journals (Sweden)

    Mahalakshmi

    2015-03-01

    Full Text Available We report a case of penile tuberculosis presenting as phimosis . A dorsal slit revealed an ulceroproliferative growth which resembled Carcinoma. The diagnosis of tuberculosis was based on histopathology. Successful treatment was achieved by Antituberculosis therapy. We report this case because of its unsual presentati on and its rarity

  5. PENILE TUBERCULOSIS PRESENTING AS PHIMOSIS

    OpenAIRE

    Mahalakshmi; Yuwarani; Narayanan; Sudha

    2015-01-01

    We report a case of penile tuberculosis presenting as phimosis . A dorsal slit revealed an ulceroproliferative growth which resembled Carcinoma. The diagnosis of tuberculosis was based on histopathology. Successful treatment was achieved by Antituberculosis therapy. We report this case because of its unsual presentati on and its rarity

  6. Neuroacanthocytosis Presenting with Psychiatric Symptoms

    OpenAIRE

    Srivatsa,; Jacob, Rajesh; Tharyan, Prathap; Vijayan, Joy; Alexander, Mathew

    2004-01-01

    An adult male presented with dyskinetic movements of the face and choreiform movements associated with dysphagia and vocaltics.Obsessive compulsive symptoms and depressive symptoms occurred 3 months after the onset of the illness.Peripheral blood smear revealed an excess of acanthocytes. A diagnosis of neuroacanthocytosis was made and he was started on treatment.

  7. Water plants past and present

    DEFF Research Database (Denmark)

    Riis, T.; Sand-Jensen, K.

    2006-01-01

    How has the condition of the environment developed during the last 100 years? This is an important question because the conditions of the past infl uence those of the present, and knowledge about this development makes it possible to evaluate the causes of changes in species richness, species...

  8. Neurobehavioral presentations of brain neoplasms.

    Science.gov (United States)

    Filley, C M; Kleinschmidt-DeMasters, B K

    1995-07-01

    We studied 8 patients with frontal or temporolimbic neoplasms who had psychiatric presentations to clarify diagnostic criteria for distinguishing psychiatric disease from structural brain lesions and to examine brain-behavior relationships associated with cerebral neoplasms using modern neuroimaging techniques. Medical records were retrospectively reviewed for evidence of neurobehavioral and neurologic manifestations, tumor histologic features, and the results of treatment. Clinical presentations were correlated with tumor location as determined by computed tomography and magnetic resonance imaging. Patients with frontal lobe tumors presented with abulia, personality change, or depression, whereas those with temporolimbic tumors had auditory and visual hallucinations, mania, panic attacks, or amnesia. After treatment, neurobehavioral syndromes abated or resolved in 7 of 8 patients. We recommend that any patient 40 years of age or older with a change in mental state, cognitive or emotional, should have neuroimaging of the brain. Any patient with a psychiatric presentation who has specific neurobehavioral or neurologic findings or an unexpectedly poor response to psychopharmacologic treatment should also have brain imaging. These case reports extend and update observations on the importance of frontal and temporolimbic systems in the pathogenesis of neurobehavioral disorders. PMID:7667978

  9. BRONCHIAL CARCINOMA PRESENTING WITH PNEUMOTHORAX

    OpenAIRE

    2006-01-01

    Spontaneous pneumothoraxs are usually caused by subpleural apical bleps but may also be secondary to metastasis to the lung and rarely primary lung cancer. We present a 56-years-old man with spontaneous pneumothorax secondary to non-small cell lung cancer. Key words: Lung cancer, spontaneus pneumothorax

  10. PEV Integration with Renewables (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Markel, T.

    2014-06-18

    This presentation discusses current research at NREL on integrating plug-in electric vehicles with the grid and using renewable energy to charge the grid. The Electric Vehicle Grid Integration (EVGI) and Integrated Network Testbed for Energy Grid Research and Technology Experimentation (INTEGRATE) are addressing the opportunities and technical requirements for vehicle grid integration that will increase marketability and lead to greater petroleum reduction.

  11. Myasthenia gravis presenting with stridor.

    OpenAIRE

    J A Hanson; Lueck, C J; Thomas, D J

    1996-01-01

    The case is described of a 72 year old woman who presented with a two year history of exertional stridor in whom the diagnosis of myasthenia gravis was delayed. Although an uncommon cause, myasthenia gravis should be included in the differential diagnosis of stridor.

  12. Testing for PV Reliability (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Kurtz, S.; Bansal, S.

    2014-09-01

    The DOE SUNSHOT workshop is seeking input from the community about PV reliability and how the DOE might address gaps in understanding. This presentation describes the types of testing that are needed for PV reliability and introduces a discussion to identify gaps in our understanding of PV reliability testing.

  13. Neonatal presentation of Caroli's disease

    OpenAIRE

    Keane, F; Wilkinson, M.; Qureshi, S; Reid, C; Baker, A.; MIELI-VERGANI, G

    1997-01-01

    A neonatal presentation of Caroli's disease with severe cardiac and progressive renal pathology is described. The availability of small paediatric endoscopes ensured early diagnosis. Despite aggressive medical management, the baby died with severe bleeding complications before potentially life saving multiple organ transplantation could take place.

 Keywords: Caroli's disease; endoscopic retrograde cholangiopancreatography; pulmonary artery stenosis

  14. Clinical Presentations of Acute Leukemia

    International Nuclear Information System (INIS)

    Objective: To document the clinical presentation and epidemiology of various types of acute leukemia with their respective referral source at a tertiary level centre in Peshawar. Study Design: An observational study. Place and Duration of Study: Department of Pathology, Hayatabad Medical Complex (HMC), Peshawar, from January 2011 to May 2012. Methodology: A total of 618 bone marrow biopsy reports were reviewed. All biopsy reports labeled as acute leukemia were reviewed for age, gender, address, referring unit, diagnosis on bone marrow examination, presenting complaints, duration of illness and findings of clinical examination. Results: Ninety-two patients were diagnosed as suffering from acute leukemias (15%). ALL was most prevalent (46%), followed by AML (38%) and undifferentiated acute leukemia (16%). Males were affected more compared to females (60% vs. 40%). ALL and AML were predominant in pediatric (64%) and adults (77%) patients respectively. Patients from Afghanistan accounted for 33% of all cases followed by Peshawar (14%). Fever (77%), pallor (33%) and bleeding disorders (23%) were the main presenting complaints. Enlargement of liver, spleen and lymph nodes together was associated with ALL compared with AML (p = 0.004). Conclusion: ALL-L1 and AML-M4 were the most common sub-types. Fever, pallor and bleeding disorders were the main presenting complaints. Enlargement of liver, spleen and lymph nodes was more frequently associated with ALL compared to AML. (author)

  15. Secondary syphilis presenting as vertigo

    International Nuclear Information System (INIS)

    Syphilis is a chronic, systemic and sexually transmitted infectious disease affecting most of the organs in the body. A young African man presented with vertigo, unsteadiness of gait and a skin rash suggestive of secondary syphilis. Diagnosis was confirmed on serology and was treated with two shots of long-acting penicillin, following which his symptoms settled. (author)

  16. Presentation of the math text

    OpenAIRE

    KREJČOVÁ, Iva

    2009-01-01

    The aim of this bachelor thesis is basic mapping out the mediums for creating mathematical texts and their presentation and the acquisition of basic user skills in the usage of these programs. These funds also compare in terms of availability and ease of use, their opportunities and quality of the output.

  17. Understanding Algorithms in Different Presentations

    Science.gov (United States)

    Csernoch, Mária; Biró, Piroska; Abari, Kálmán; Máth, János

    2015-01-01

    Within the framework of the Testing Algorithmic and Application Skills project we tested first year students of Informatics at the beginning of their tertiary education. We were focusing on the students' level of understanding in different programming environments. In the present paper we provide the results from the University of Debrecen, the…

  18. Porphyria Presenting as Diffuse Encephalopathy

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2005-05-01

    Full Text Available An 18-year-old female presenting with seizures, myalgias, abdominal pain, headache and vomiting had multiple large contrast-enhancing white matter lesions on MRI and was diagnosed with acute intermittent porphyria (AIP, in a report from the Department of Neurology, Mayo Clinic, Rochester, MN.

  19. Pronunciation Teaching: Past and Present

    Directory of Open Access Journals (Sweden)

    Saeed Ketabi

    2015-09-01

    Full Text Available Pronunciation, despite being known as an important component of language learning, has not been awarded due attention within the field of language education. This article is a humble attempt to present an overview of the history of pronunciation teaching. Different approaches and methods of language teaching from the late nineteenth century into the new millennium are reviewed and discussed with regard to their stance in pronunciation instruction. Recent trends and issues of pronunciation teaching, e.g. intelligibility and Lingua Franca Core are also highlighted. Discussions like the present one might be beneficial in gaining a better understanding and evaluation of the status quo in order to improve and enhance the status of pronunciation instruction within language pedagogy.Keywords: Pronunciation instruction, Teaching methods, Intelligibility, Lingua Franca Core

  20. Clinical presentations of food allergy.

    Science.gov (United States)

    Mansoor, Darlene K; Sharma, Hemant P

    2011-04-01

    Food allergies are immune-mediated responses to food proteins. Because of differences in the underlying immunologic mechanisms, there are varying clinical presentations of food allergy. This article discusses the manifestations of IgE-mediated disorders, including urticaria and angioedema, rhinoconjunctivitis, asthma, gastrointestinal anaphylaxis, generalized anaphylaxis, food-dependent exercise-induced anaphylaxis, and oral allergy syndrome. It also reviews the presentations of mixed IgE- and cell-mediated disorders, including atopic dermatitis and eosinophilic gastrointestinal disorders. Finally, the manifestations of cell-mediated food allergies are discussed, including dietary protein-induced proctitis and proctocolitis, food protein-induced enterocolitis syndrome, celiac disease, and food-induced pulmonary hemosiderosis. PMID:21453804

  1. RTNS-II: present status

    Energy Technology Data Exchange (ETDEWEB)

    Heikkinen, D.W.; Logan, C.M.

    1980-10-01

    The present status of the RTNS-II facility is described and typical operating parameters are given. A brief discussion is given of the methods used in production of the TiT/sub 2/ targets as well as their performance and tritium handling at RTNS-II. The various types of non-interactive beam diagnostics presently in use at the neutron sources are outlined. The on-line computer system which provides a time history of an irradiation and records target performance is described. Examples are listed of several representative experimental programs which have been carried out thus far at RTNS-II. These include both active and passive experiments. Finally, several of the major improvements to the facility made since the beginning of the experimental program are given.

  2. Flat strips. A case presentation.

    Directory of Open Access Journals (Sweden)

    Margarita Espinosa Jiménez

    2003-07-01

    Full Text Available This research paper presents a case of a 12 year old . Give with Angle´s Malocclusion class II, division I, with a 10 mms protuberance and an overpass of complete crown to whom a functional device with plane trail was applied . At 8 months follow up molar relation class I , a 4 mms protuberance and an overpass of the third part of the crown is observed. These results have been assessed as a satisfactory evolution of the patient.

  3. Presentations of Graph Braid Groups

    OpenAIRE

    Farley, Daniel; Sabalka, Lucas

    2009-01-01

    Let G be a graph. The (unlabeled) configuration space of n points on G is the space of all n-element subsets of G. The fundamental group of such a configuration space is called a graph braid group. We use a version of discrete Morse theory to compute presentations of all graph braid groups, for all finite connected graphs G and all natural numbers n.

  4. An Early Presenting Esophageal Schwannoma

    OpenAIRE

    Choo, Shelly S.; Maurice Smith; Ashley Cimino-Mathews; Yang, Stephen C.

    2011-01-01

    Esophageal schwannoma is a rare diagnosis and historically has been a tumor of middle-aged females. We report a case of a 22-year-old male presenting initially with dyspnea secondary to tracheal compression from an 8 × 6 × 3.0 cm esophageal schwannoma. The tumor was surgically resected, and diagnosis was confirmed with immunohistochemical and pathological studies. We report the youngest case of esophageal schwannoma in an otherwise healthy individual.

  5. Nocardial mycetoma: Diverse clinical presentations

    OpenAIRE

    Sharma Nand; Mahajan Vikram; Agarwal Santwana; Katoch Vishwa; Das Ram; Kashyap Meera; Gupta Poonam; Verma Ghanshyam

    2008-01-01

    Nocardia spp are gram-positive, aerobic, acid-fast bacteria which exist as saprophytes in nature. Invasive disseminated infections are particularly common in immunocompromised or debilitated hosts. Superficial infections with Nocardia spp occur as a result of local trauma and contamination of the wound. Clinically, it presents as acute infection (abscesses or cellulitis), mycetoma, or sporotrichoid infection. Differential diagnosis includes eumycetoma, chromomycosis, blastomycosis, coccidioid...

  6. Sound and computer information presentation

    Energy Technology Data Exchange (ETDEWEB)

    Bly, S

    1982-03-01

    This thesis examines the use of sound to present data. Computer graphics currently offers a vast array of techniques for communicating data to analysts. Graphics is limited, however, by the number of dimensions that can be perceived at one time, by the types of data that lend themselves to visual representation, and by the necessary eye focus on the output. Sound offers an enhancement and an alternative to graphic tools. Multivariate, logarithmic, and time-varying data provide examples for aural representation. For each of these three types of data, the thesis suggests a method of encoding the information into sound and presents various applications. Data values were mapped to sound characteristics such as pitch and volume so that information was presented as sets or sequences of notes. In all cases, the resulting sounds conveyed information in a manner consistent with prior knowledge of the data. Experiments showed that sound does convey information accurately and that sound can enhance graphic presentations. Subjects were tested on their ability to distinguish between two sources of test items. In the first phase of the experiments, subjects discriminated between two 6-dimensional data sets represented in sound. In the second phase of the experiment, 75 subjects were selected and assigned to one of three groups. The first group of 25 heard test items, the second group saw test items, and the third group both heard and saw the test items. The average percentage correct was 64.5% for the sound-only group, 62% for the graphics-only group, and 69% for the sound and graphics group. In the third phase, additional experiments focused on the mapping between data values and sound characteristics and on the training methods.

  7. Ocular toxocariasis. A case presentation

    Directory of Open Access Journals (Sweden)

    Mariela Julia Curbelo Gómez

    2008-12-01

    Full Text Available A clinical case on ocular toxocariasis is presented. The clinical manifestations were pain and red eye in a four year-old child. A prior acute uveitis in the LE was found in the physical ocular exam. Vitrea band that was out of the superior edge of papila and a marginal granuloma were found in the eyes fundus. The patient was admitted and treated with oral corticoids and oral antihelmintics

  8. Windows Presentation Foundation a kytara

    OpenAIRE

    KRAJČOVIČ, Jan

    2010-01-01

    This work deals with general overview about technology of Windows Presentation Foundation which is specialized for creating aplications with user friendly interface designated for operating systems Windows Vista (or later). By using technology of WPF author of this thesis created tutorial for playing guitar. Few of students will test the program. Main goal of this thesis is evaluation of testing student´s achieved results.

  9. SIGMOID VOLVULUS – CASE PRESENTATION

    OpenAIRE

    Maria Gabriela Roşca; Radu, I.; V. Scripcariu

    2008-01-01

    Background: Sigmoid volvulus the most common type of volvulus of the gastrointestinal tract is the third leading cause of large bowel obstruction. This condition is responsible for 5-7% of all intestinal obstructions. It is particularly common in elderly persons. However, some reports suggest that sigmoid volvulus occurs in younger age-groups more frequently than has been reported. Method: We present the case of a 72 years old patient admitted in our surgical unit in emergency, for an importa...

  10. PSYCHIATRY-PAST, PRESENT & FUTURE

    OpenAIRE

    Doongaji, Dinshaw R

    1997-01-01

    An overview of psychiatry during the last three decades as practised in a general teaching hospital is presented. Psychiatry as an academic subject has matured tremendously during this period. The empirical treatments of the 1950s and the 1960s which evoke nostalgic memories, have been replaced by modern methods of treatment. However, there is a need to exercise caution against the blind acceptance of new and sophisticated research findings in biological psychiatry. Inspite of the bright futu...

  11. Presentation of Ligands on Hydroxylapatite

    Science.gov (United States)

    Chu, Barbara C. F.; Orgel, Leslie E.

    1997-01-01

    Conjugates of biotin with the decamer of glutamic acid (glu(sub 10)) and the trimer of D,L-2-amino-5-phosphonovaleric acid (I) have been synthesized, and it has been shown that they mediate the binding of avidin to hydroxylapatite. In a similar way a conjugate of methotrexate with glu(sub 10) mediates the binding of dihydrofolate reductase to the mineral. The presentation of ligands on the hydroxylapatite component of bone may find applications in clinical medicine.

  12. Syphilis: presentations in general medicine.

    Science.gov (United States)

    Nyatsanza, Farai; Tipple, Craig

    2016-04-01

    Syphilis is caused by the spirochete bacteriumTreponema pallidumand can be transmitted both sexually and from mother to child.T pallidumcan infect any organ and produces a clinical disease with a relapsing and remitting course. It is not hard to see, therefore, why it is often described as the great mimic. In this review, we provide an update of modern syphilis epidemiology, clinical presentations, and testing and treatment strategies. PMID:27037391

  13. Windows Presentation Foundation & Data Binding

    OpenAIRE

    JANDA, Vilém

    2010-01-01

    The aim of this work is a course in the form of e-learning study materials for the interpretation of technology Data Binding in Windows Presentation Foundation (WPF). In the first, mostly theoretical part will be done a description and interpretation of the elements of technology, focusing on WPF Data Binding. In the second part, is available methodology and training course with their own interpretive audio-visual files for self-study. The lectures are supplemented by solved examples, and exa...

  14. Supernumerary breast. A case Presentation

    Directory of Open Access Journals (Sweden)

    Juan Miguel Guerra Cabrera

    2010-07-01

    Full Text Available Congenital malformations of the breast appear in 10 % of the population. The existence of mammary tissue at any line of the breast is classified according to Kajava’s categories into eight classes which differ one from the other in the presence or absence of the areola of the breast, nipple and glandular tissue. This report presents a case of a puerpera who had delivered her child seven days before her attendance to hospital. She presented with discharge from her both axillae. On physical examination, a supernumerary nipple with milky secretion out from it was found in her right axilla and secretion throughout the contralateral axilla through the skin pores, with absence of nipple and areola in that axillary region. The echographic study revealed the presence of bilateral ectopic mammary tissue. This case belongs to Kajava’s class IV classification in the left axilla and a variery of Type I in the right axilla. In facing a mammary malformation, a conservative attitude seems to be the most appropriate although esthetics requires surgery. To keep into account the presence of supernumerary breasts will be a need for the prevention of breast cancer. This case has been presented due to all these reasons and the unusual features of this case.

  15. Giving a grand rounds presentation.

    Science.gov (United States)

    Morrison, Laura J; Portenoy, Russell

    2010-12-01

    Giving a Grand Rounds presentation provides the hospice and palliative medicine subspecialist with the occasion to participate in a time-honored and respected event. It remains an opportunity to promote the discipline, support institutional culture change, and favorably influence the attitudes, knowledge, skills, and performance of colleagues. For those pursuing academic careers, it also is a chance to establish academic currency and develop teaching and presentation skills. In most academic settings, the format of Grand Rounds has shifted over time from a patient and problem-based discussion to a didactic, topic-focused lecture. A body of literature questions the value of this shift toward a more passive learner. Limited evidence prevents a definitive answer but many advocate for the integration of more interactive methods to improve the effectiveness of Grand Rounds. This article provides a flexible framework to guide those preparing to give a Grand Rounds and those teaching and supporting others to do so. To do this well, adult learning principles must be thoughtfully incorporated into a presentation style and method appropriate to the venue. The approach emphasizes learner-centeredness, interactive strategies, and evaluation. Room for creativity exists at every step and can add enjoyment and challenge along the way. PMID:21155643

  16. Nocardial mycetoma: Diverse clinical presentations

    Directory of Open Access Journals (Sweden)

    Sharma Nand

    2008-01-01

    Full Text Available Nocardia spp are gram-positive, aerobic, acid-fast bacteria which exist as saprophytes in nature. Invasive disseminated infections are particularly common in immunocompromised or debilitated hosts. Superficial infections with Nocardia spp occur as a result of local trauma and contamination of the wound. Clinically, it presents as acute infection (abscesses or cellulitis, mycetoma, or sporotrichoid infection. Differential diagnosis includes eumycetoma, chromomycosis, blastomycosis, coccidioidomycosis, sporotrichosis, tuberculosis, botryomycosis, syphilis, yaws, and neoplasia. Its diagnosis is confirmed by demonstrating the causative organism in exudates (as granules, tissue specimens, or cultures. Early diagnosis will obviate need for drastic surgical measures as early institution of chemotherapy is effective in most patients. However, its diagnosis is often delayed due to diverse clinical presentations and for want of clinical suspicion, particularly in non-endemic areas. This paper presents 4 clinical forms of this not so uncommon disease, emphasizing the importance of high index of clinical suspicion, especially in non-endemic regions; and the significance of repeated examination of exudates for Nocardia granules for an early diagnosis.

  17. Cartography past, present and future

    CERN Document Server

    Rhind, DW

    2013-01-01

    Making maps dates back at least four thousand years and it is widely recognised that many maps are of great historical value and present a skilled method of summarising the real world on a sheet of paper. Less well known is the judgement involved in the selection and simplification of features, the complex transformation of space and the exacting standards which are needed in cartography. This book is primarily a tribute to Professor F.J. Ormeling, former President and Secretary/Treasurer of the ICA and gives a wide ranging review of the current status of cartography, how this status was atta

  18. Meningitis, clinical presentation of tetanus.

    Science.gov (United States)

    Moniuszko, Anna; Zajkowska, Agata; Tumiel, Ewa; Rutkowski, Krzysztof; Czupryna, Piotr; Pancewicz, Sławomir; Rutkowski, Ryszard; Zdrodowska, Agnieszka; Zajkowska, Joanna

    2015-01-01

    Background. Tetanus is an acute disease caused by a neurotoxin produced by Clostridium tetani. Tetanus immunization has been available since the late 1930s but sporadic cases still occur, usually in incompletely vaccinated or unvaccinated individuals. Case Report. An elderly previously vaccinated female contracted tetanus following foot injury. Clinically she presented with meningitis causing diagnostic and therapeutic delays. Why Should Physician Be Aware of This? Even in developed countries the differential diagnosis of meningitis, especially in the elderly, should include tetanus. Treatment in intensive care unit is required. General population might benefit from vaccine boosters and education on this potentially fatal disease. PMID:25789186

  19. Session: Test and Evaluation (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Marion, B.; Hanley, C.

    2008-04-01

    The overall goal of this presentation is: (1) provide test and evaluation of PV cells/modules/systems to TPP participants, other PV industry, labs, and universities in support of technology optimization efforts sponsored by DOE's Solar Program and the SAI; (2) support commercial and emerging technology development; (3) provide component and system performance data to improve and validate system performance models; (4) provide T and E support for reliability activities; and (5) priority is placed on TPP's and other solicitations.

  20. Neuromodulation: present and emerging methods

    Directory of Open Access Journals (Sweden)

    Song Luan

    2014-07-01

    Full Text Available Neuromodulation has wide ranging potential applications in replacing impaired neural function (prosthetics, as a novel form of medical treatment (therapy, and as a tool for investigating neurons and neural function (research. Voltage and current controlled electrical neural stimulation (ENS are methods that have already been widely applied in both neuroscience and clinical practice for neuroprosthetics. However, there are numerous alternative methods of stimulating or inhibiting neurons. This paper reviews the state-of-the-art in ENS as well as alternative neuromodulation techniques - presenting the operational concepts, technical implementation and limitations - in order to inform system design choices.

  1. Diabetic Myonecrosis: An Atypical Presentation

    Directory of Open Access Journals (Sweden)

    José Hernán Martínez

    2013-01-01

    Full Text Available Diabetic myonecrosis is a frequently unrecognized complication of longstanding and poorly controlled diabetes mellitus. The clinical presentation is swelling, pain, and tenderness of the involved muscle, most commonly the thigh muscles. Management consists of conservative measures including analgesia and rest. Short-term prognosis is good, but long-term prognosis is poor with most patients dying within 5 years. Failure to properly identify this condition will expose the patient to aggressive measures that could result in increased morbidity. To our knowledge this is the first case reported in which there was involvement of multiple muscle groups including upper and lower limbs.

  2. Presentation at Innoventure Annual Competition

    Energy Technology Data Exchange (ETDEWEB)

    None

    2010-03-31

    This report documents the components of the workshop presented at the recent annual competition for the Innoventure program. The goal of the workshop was to focus on the delivery of science, technology, engineering, and math (STEM) concepts in a hands-on experiential learning format to increase interest in national security careers at NNSA, most of which are in the STEM fields. This work is a part of the National Security Preparedness Project (NSPP), being performed under a Department of Energy (DOE)/National Nuclear Security Administration (NNSA) grant.

  3. Present status of institutional informatics

    International Nuclear Information System (INIS)

    It is described the computer sources (hardware, logic and humans) that to count the National Institute of Nuclear Research for to satisfy the basic necessities of information handling, so much in the management area as technical and for researching purposes, the institutions support as the National Autonomous University of Mexico for to be useful its supercomputer physical resources. It is presented the actual situation and the plans to the future as for central computer equipment and microcomputers, just as the communications infrastructure and electrical support. (Author)

  4. Commercial proteases: present and future.

    Science.gov (United States)

    Li, Qing; Yi, Li; Marek, Peter; Iverson, Brent L

    2013-04-17

    This review presents a brief overview of the general categories of commercially used proteases, and critically surveys the successful strategies currently being used to improve the properties of proteases for various commercial purposes. We describe the broad application of proteases in laundry detergents, food processing, and the leather industry. The review also introduces the expanding development of proteases as a class of therapeutic agents, as well as highlighting recent progress in the field of protease engineering. The potential commercial applications of proteases are rapidly growing as recent technological advances are producing proteases with novel properties and substrate specificities. PMID:23318711

  5. Meningitis, Clinical Presentation of Tetanus

    Directory of Open Access Journals (Sweden)

    Anna Moniuszko

    2015-01-01

    Full Text Available Background. Tetanus is an acute disease caused by a neurotoxin produced by Clostridium tetani. Tetanus immunization has been available since the late 1930s but sporadic cases still occur, usually in incompletely vaccinated or unvaccinated individuals. Case Report. An elderly previously vaccinated female contracted tetanus following foot injury. Clinically she presented with meningitis causing diagnostic and therapeutic delays. Why Should Physician Be Aware of This? Even in developed countries the differential diagnosis of meningitis, especially in the elderly, should include tetanus. Treatment in intensive care unit is required. General population might benefit from vaccine boosters and education on this potentially fatal disease.

  6. Big Data: present and future

    Directory of Open Access Journals (Sweden)

    Mircea Raducu TRIFU

    2014-05-01

    Full Text Available The paper explains the importance of the Big Data concept, a concept that even now, after years of development, is for the most companies just a cool keyword. The paper also describes the level of the actual big data development and the things it can do, and also the things that can be done in the near future. The paper focuses on explaining to nontechnical and non-database related technical specialists what basically is big data, presents the three most important V's, as well as the new ones, the most important solutions used by companies like Google or Amazon, as well as some interesting perceptions based on this subject.

  7. Presentation Extensions of the SOAP

    Science.gov (United States)

    Carnright, Robert; Stodden, David; Coggi, John

    2009-01-01

    A set of extensions of the Satellite Orbit Analysis Program (SOAP) enables simultaneous and/or sequential presentation of information from multiple sources. SOAP is used in the aerospace community as a means of collaborative visualization and analysis of data on planned spacecraft missions. The following definitions of terms also describe the display modalities of SOAP as now extended: In SOAP terminology, View signifies an animated three-dimensional (3D) scene, two-dimensional still image, plot of numerical data, or any other visible display derived from a computational simulation or other data source; a) "Viewport" signifies a rectangular portion of a computer-display window containing a view; b) "Palette" signifies a collection of one or more viewports configured for simultaneous (split-screen) display in the same window; c) "Slide" signifies a palette with a beginning and ending time and an animation time step; and d) "Presentation" signifies a prescribed sequence of slides. For example, multiple 3D views from different locations can be crafted for simultaneous display and combined with numerical plots and other representations of data for both qualitative and quantitative analysis. The resulting sets of views can be temporally sequenced to convey visual impressions of a sequence of events for a planned mission.

  8. Case presentation – thyroid lymphoma

    Directory of Open Access Journals (Sweden)

    Belkisa Izić

    2011-11-01

    Full Text Available Malignant tumors of the thyroid gland account for about 1% of thenewly diagnosed malignant tumors each year, and their incidence inwomen is twice the incidence in men. According to the WHO classification (2004 thyroid tumors are divided into: carcinoma of the thyroid, adenoma and similar tumors, and other thyroid tumors which include: teratomas, angiosarcomas, paragangliomas and others, as well as primary lymphomas and plasmacytomas. Primary thyroid lymphomasare defined as lymphomas which originate in the thyroid gland. This study presents the case of a 68-year-old patient with a thyroid lymphoma, which caused compression of the airways. In the patientpresented there was reduced activity of the thyroid gland. The dominant symptoms were: breathing difficulties, hoarse voice and the enlargement of the thyroid. An ultrasound examination was performedbefore surgery on the neck, which showed a multinodular thyroid,with compromised and compressed trachea to the right and rear. Anemergency surgical procedure was performed to reduce the tumor.Pathohistological diagnosis confirmed diffuse large B cell lymphoma.The aim of the study was to present a patient with a thyroid lymphoma, who had previously not had any immunological changes to the gland,that is, she had not had any chronic lymphocyte thyroiditis, but due to the compressive syndrome it was necessary to perform an emergencysurgical procedure to reduce the tumor.

  9. Clinical presentation of cerebral aneurysms

    Energy Technology Data Exchange (ETDEWEB)

    Cianfoni, Alessandro [Neurocentro della Svizzera Italiana, Ospedale Civico di Lugano, via Tesserete, 46, 6900 Lugano (Switzerland); Pravatà, Emanuele, E-mail: emanuele.pravata@gmail.com [Neurocentro della Svizzera Italiana, Ospedale Civico di Lugano, via Tesserete, 46, 6900 Lugano (Switzerland); De Blasi, Roberto [Neurocentro della Svizzera Italiana, Ospedale Civico di Lugano, via Tesserete, 46, 6900 Lugano (Switzerland); Tschuor, Costa Silvia [Dipartimento di Radiologia, Ospedale Civico di Lugano, via Tesserete, 46, 6900 Lugano (Switzerland); Bonaldi, Giuseppe [U.O. Neuroradiologia, Ospedali Riuniti di Bergamo, Largo Barozzi, 1, 24128 Bergamo (Italy)

    2013-10-01

    Presentation of a cerebral aneurysm can be incidental, discovered at imaging obtained for unrelated causes, can occur in the occasion of imaging obtained for symptoms possibly or likely related to the presence of an unruptured aneurysm, or can occur with signs and symptoms at the time of aneurismal rupture. Most unruptured intracranial aneurysms are thought to be asymptomatic, or present with vague or non-specific symptoms like headache or dizziness. Isolated oculomotor nerve palsies, however, may typically indicate the presence of a posterior circulation aneurysm. Ruptured intracranial aneurysms are by far the most common cause of non-traumatic subarachnoid hemorrhage and represent a neurological emergency with potentially devastating consequences. Subarachnoid hemorrhage may be easily suspected in the presence of sudden and severe headache, vomiting, meningism signs, and/or altered mental status. However, failure to recognize milder and more ambiguous clinical pictures may result in a delayed or missed diagnosis. In this paper we will describe the clinical spectrum of unruptured and ruptured intracranial aneurysms by discussing both typical and uncommon clinical features emerging from the literature review. We will additionally provide the reader with descriptions of the underlying pathophysiologic mechanisms, and main diagnostic pitfalls.

  10. Clinical presentation of cerebral aneurysms

    International Nuclear Information System (INIS)

    Presentation of a cerebral aneurysm can be incidental, discovered at imaging obtained for unrelated causes, can occur in the occasion of imaging obtained for symptoms possibly or likely related to the presence of an unruptured aneurysm, or can occur with signs and symptoms at the time of aneurismal rupture. Most unruptured intracranial aneurysms are thought to be asymptomatic, or present with vague or non-specific symptoms like headache or dizziness. Isolated oculomotor nerve palsies, however, may typically indicate the presence of a posterior circulation aneurysm. Ruptured intracranial aneurysms are by far the most common cause of non-traumatic subarachnoid hemorrhage and represent a neurological emergency with potentially devastating consequences. Subarachnoid hemorrhage may be easily suspected in the presence of sudden and severe headache, vomiting, meningism signs, and/or altered mental status. However, failure to recognize milder and more ambiguous clinical pictures may result in a delayed or missed diagnosis. In this paper we will describe the clinical spectrum of unruptured and ruptured intracranial aneurysms by discussing both typical and uncommon clinical features emerging from the literature review. We will additionally provide the reader with descriptions of the underlying pathophysiologic mechanisms, and main diagnostic pitfalls

  11. Atypical presentations of neuromyelitis optica

    Directory of Open Access Journals (Sweden)

    Douglas Sato

    2011-10-01

    Full Text Available Neuromyelitis optica (NMO is an inflammatory disease of central nervous system classically characterized by acute, severe episodes of optic neuritis and longitudinally extensive transverse myelitis, usually with a relapsing course. The identification of an autoantibody exclusively detected in NMO patients against aquaporin-4 (AQP-4 has allowed identification of cases beyond the classical phenotype. Brain lesions, once thought as infrequent, can be observed in NMO patients, but lesions have different characteristics from the ones seen in multiple sclerosis. Additionally, some AQP-4 antibody positive patients may present with a variety of symptoms not being restricted to optic neuritis and acute myelitis during the first attack or in a relapse. Examples are not limited to, but may include patients only with brain and/or brainstem lesions, narcolepsy with hypothalamic lesions or patients with intractable hiccups, nausea and vomiting. The prompt identification of NMO patients with atypical presentations may benefit these patients with institution of early treatment to reduce disability and prevent further attacks.

  12. Present status of reactor PIK

    International Nuclear Information System (INIS)

    This presentation shows the present status pf the Pressurized Beam Research reactor PIK, located at Gatchina near St.Petersburg. The construction started in 1976 with the aim to provide a useful experimental facility at lowest cost. It is 100 MW, water cooled and water moderated reactor with a heavy water reflector. The possibility of changing the dimensions and composition of the core is planned. Control system will have 2 absorbing rods for rapid control, 8 safety rods made of europium plates; and gadolinium nitrate dissolved in water for smooth reactivity control. A 3-circuit cooling system is planned to prevent air contamination in case of damage of the heat exchanger in the primary loop. Reactor shield will consist of 1 m thick reflector, with additional 0.5 m of heterogeneous iron-water shield, 0.9 m of heavy concrete; and 1 m of moveable shield. A comparison of PIK and Grenoble reactor shows some advantages of PIK: three time higher neutron beam intensity, three times higher thermal neutron flux in the neutron trap (existing only in PIK) than in the reflector; PIK has a moveable shield for special precise measurements

  13. Speaker's presentations. Energy supply security

    International Nuclear Information System (INIS)

    This document is a collection of most of the papers used by the speakers of the European Seminar on Energy Supply Security organised in Paris (at the French Ministry of Economy, Finance and Industry) on 24 November 2000 by the General Direction of Energy and Raw Materials, in co-operation with the European Commission and the French Planning Office. About 250 attendees were present, including a lot of high level Civil Servants from the 15 European State members, and their questions have allowed to create a rich debate. It took place five days before the publication, on 29 November 2000, by the European Commission, of the Green Paper 'Towards a European Strategy for the Security of Energy Supply'. This French initiative, which took place within the framework of the European Presidency of the European Union, during the second half-year 2000. will bring a first impetus to the brainstorming launched by the Commission. (author)

  14. Jefferson Lab: Present and Future

    Science.gov (United States)

    Rossi, Patrizia

    2016-04-01

    The continuous electron beam accelerator facility and associated experimental equipment at Jefferson Lab comprise a unique facility for nuclear physics research whose upgrade is presently underway, with completion expected in 2017. The upgraded facility will accelerate electron beams to 11 GeV for experiments in the existing Halls A, B and C. In addition, a 12 GeV beam can be provided to a new experimental hall, Hall D, to generate a 9 GeV tagged photon beam. This upgrade will enable a new experimental program with substantial discovery potential to address important topics in hadronic, nuclear, and electroweak physics. Further in the future, it is envisioned that the Laboratory will evolve into an electron-ion colliding beam facility.

  15. Multiple Presentations of Brain TB

    Directory of Open Access Journals (Sweden)

    H. Kharazi

    2008-01-01

    Full Text Available Tuberculosis of the central nervous system is an im-portant cause of mortality and morbidity."nPrompt diagnosis and early treatment are extremely important to reduce its morbidity and mortality. The main forms of central nervous system tuberculosis are represented by tuberculosis meningitis, meningeal or parenchymal tuberculomas, and tuberculosis abscess formation. Sequels consist of hydrocephalus, calcifi-cations, and areas of encephalomalacia."nCT is the diagnostic imaging modality in many clini-cal settings to demonstrate the various aspects of cra-nial tuberculosis on initial presentation and to moni-tor the evolution of the disease and response to ther-apy. In this review we illustrate CT scan findings of intracranial lesions of tuberculosis in our patients.

  16. Present status of JENDL-2

    International Nuclear Information System (INIS)

    The evaluation and compilation work for JENDL-2 was started in 1977. The purpose of JENDL-2 is to modify the defects of JENDL-1 and to extend the application fields of JENDL to thermal reactor, fusion and shielding fields as well as fast reactor calculation. The number of nuclides of which data are stored in JENDL-2 will be increased to a hundred and a few tens. The data of important nuclides such as structural materials and heavy nuclides have been compiled already. The compilation of all the data will have been completed in 1981. In this report, the present status of JENDL-2 is discussed, especially the data of important nuclides. (author)

  17. Jefferson Lab: Present and Future

    Science.gov (United States)

    Rossi, Patrizia

    2016-08-01

    The continuous electron beam accelerator facility and associated experimental equipment at Jefferson Lab comprise a unique facility for nuclear physics research whose upgrade is presently underway, with completion expected in 2017. The upgraded facility will accelerate electron beams to 11 GeV for experiments in the existing Halls A, B and C. In addition, a 12 GeV beam can be provided to a new experimental hall, Hall D, to generate a 9 GeV tagged photon beam. This upgrade will enable a new experimental program with substantial discovery potential to address important topics in hadronic, nuclear, and electroweak physics. Further in the future, it is envisioned that the Laboratory will evolve into an electron-ion colliding beam facility.

  18. Uncommon presentation of pulmonary aspergilloma

    Directory of Open Access Journals (Sweden)

    Baradkar V

    2009-01-01

    Full Text Available Cases of pulmonary aspergilloma without any predisposing factors are rarely reported. Clinical presentation varies from case to case. Here, we report a case of pulmonary aspergilloma in a 60-year-old male patient who was admitted to the Intensive Respiratory Care Unit with spontaneous pneumothorax. The patient had a history of dyspnea on exertion since 9 months and mild haemoptysis since the last 6 months. A computerised tomographic scan of the lungs showed a lesion in the left main bronchus along with obstructive emphysema of the right lung, moderate pneumothorax and mediastinal emphysema. Bronchoscopy was performed and the biopsy samples were processed for histopathological examination and culture on Sabouraud′s dextrose agar, which yielded growth of Aspergillus flavus. Repeat sputum samples also yielded the growth of A. flavus . The patient responded to intravenous liposomaamphotericin B and intercostal drainage.

  19. Safeguards instrumentation: past, present, future

    International Nuclear Information System (INIS)

    Instruments are essential for accounting, for surveillance and for protection of nuclear materials. The development and application of such instrumentation is reviewed, with special attention to international safeguards applications. Active and passive nondestructive assay techniques are some 25 years of age. The important advances have been in learning how to use them effectively for specific applications, accompanied by major advances in radiation detectors, electronics, and, more recently, in mini-computers. The progress in seals has been disappointingly slow. Surveillance cameras have been widely used for many applications other than safeguards. The revolution in TV technology will have important implications. More sophisticated containment/surveillance equipment is being developed but has yet to be exploited. On the basis of this history, some expectations for instrumentation in the near future are presented

  20. Neurocysticercosis presenting as pseudobulbar palsy

    Directory of Open Access Journals (Sweden)

    Arinaganahalli Subbanna Praveen Kumar

    2014-01-01

    Full Text Available Neurocysticercosis (NCC is the most common helminthic infestation of the central nervous system (CNS and a leading cause of acquired epilepsy worldwide. The common manifestations of NCC are seizures and headache. The NCC as a cause of pseudobulbar palsy is very unusual and not reported yet in the literature. A pseudobulbar palsy can occur in any disorder that causes bilateral corticobulbar disease. The common etiologies of pseudobulbar palsy are vascular, demyelinative, or motor neuron disease. We report a 38-year-old female patient who presented with partial seizures and pseudobulbar palsy. The MRI brain showed multiple small cysts with scolex in both the cerebral hemispheres and a giant intraparenchymal cyst. Our patient responded well to standard treatment of neurocysticercosis and antiepileptics.

  1. Unusual presentation of spinal lipomatosis

    Directory of Open Access Journals (Sweden)

    Stephenson W

    2014-09-01

    Full Text Available William Stephenson,1 Matthew J Kauflin2,3 1Primary Care, Huntington Veteran's Affairs Medical Center, Huntington, WV, USA; 2Department of Pharmacy, Grandview Medical Center, Dayton, Ohio, OH, USA; 3Ohio Northern University, Ada, Ohio, OH, USA Abstract: Spinal epidural lipomatosis (SEL is a rare condition characterized by overgrowth of normal adipose tissue in the extradural space within the spinal canal that can lead to significant spinal cord compression. It is most commonly reported in patients receiving chronic glucocorticoid therapy. Other causes can include obesity and hypercortisolism. Occasionally, idiopathic SEL will occur in patients with no known risk factors, but cases are more generally reported in obesity and males. We present the case of a 35 year-old non-obese woman found to have rapidly progressive SEL that was not associated with any of the common causes of the disorder. Keywords: lipomatosis, laminectomy, hypercortisolism

  2. Site selection: Past and present

    International Nuclear Information System (INIS)

    Site selection has been going on since the earliest times. The process has evolved through the Industrial Revolution to the present period of exploding population and environmental awareness. Now the work must be done both with increasing sophistication and greater transparency. Modern techniques for site selection have been developed during the last two decades or so, utilizing a teachable body of knowledge and a growing literature. Many firms and individuals have contributed to this growing field. The driving force has been the need for such a process in siting and licensing of critical facilities such as nuclear power plants. A list of crucial, documented steps for identifying social impacts and acceptability are provided. A recent innovation is the self-selection method developed by government. The Superconducting Supercollider serves as an example of this approach. Geological or geologically dependent factors often dominate the process. The role as engineering and environmental geoscientists is to provide responsible leadership, consultation, and communication to the effort

  3. Splenic abscess: a rare presentation

    Directory of Open Access Journals (Sweden)

    Mohit Bhatia

    2015-01-01

    Full Text Available Splenic abscess is a rare clinical entity with an incidence of 0.2-0.7% in autopsy-based studies. When untreated, splenic abscess is associated with nearly 100% mortality; in treated patients, the mortality rate is 16.6% during the first 90 days. It mostly occurs in patients with neoplasia, immunodeficiency, trauma, diabetes or splenic infarct. The incidence of splenic abscess is thought to be growing because of the increase in the number of immunocompromised patients who are particularly at risk for this disease and also because of the widespread use of diagnostic modalities. However, the optimal treatment for this remains unclear. We present a case of a 42-year-old man diagnosed with multiloculated splenic abscess and was subjected to splenectomy.

  4. Tritium practices past and present

    International Nuclear Information System (INIS)

    History of the production and use of tritium, as well as handling techniques, are reviewed. Handling techniques first used at Lawrence Livermore National Laboratory made use of glass vacuum systems and relatively crude ion chambers for monitoring airborne activity. The first use of inert atmosphere glove boxes demonstrated that uptake through the skin could be a serious personnel exposure problem. Growing environmental concerns in the early 1970's resulted in the implementation by the Atomic Energy Commission of a new criteria to limit atmospheric tritium releases to levels as low as practicable. An important result of the new criteria was the development of containment and recovery systems to capture tritium rather than vent it to the atmosphere. The Sandia National Laboratories, Livermore, Tritium Research Laboratory containment and decontamination systems are presented as a typical example of this technology. The application of computers to control systems is expected to provide the greatest potential for change in future tritium handling practices

  5. Different presentations of pulmonary criptococosis

    International Nuclear Information System (INIS)

    We presented 4 cases studies of criptococosis, all of them with pulmonary compromise, diagnosed at Hospital Santa Clara in a period of 5 years. It's important to note that none of the patients were HIV positive. In the first case studied the cellular immune compromise has, a multifactorial origin: rheumatoid arthritis and the administration of corticoids. In the second case studied, SLE can explain its origin. In the third case studied, because of the short hospital stay, the investigation with respect to the etiology of the immune-compromise was limited. In the fourth case studied, because of a low CD4 count Elisa immunoassay for HIV was repeated without its confirmation. Spontaneous recuperation was obtained, being free of infection for a period of five years

  6. Director general presentation to personnel

    CERN Multimedia

    2016-01-01

    Dear Colleagues, Many important discussions are scheduled for the upcoming Council Week (13-17 June) on topics including the Medium-Term Plan, the Pension Fund and other matters of great relevance to us.   I would therefore like to share the main outcome of the week with you and I invite you to join me and the Directors in the Main Auditorium at 10 a.m. on Thursday 23 June. The meeting will last about one hour and a webcast will also be available. Best regards, Fabiola Gianotti DG presentation to personnel Thursday 23 June at 10 am Main Auditorium Retransmission in Council Chamber, IT Auditorium, Kjell Jonhsen Auditorium, Prevessin 864-1-C02 Webcast on cern.ch/webcast More information on the event page.

  7. DNA Computer; Present and Future

    Directory of Open Access Journals (Sweden)

    Amir Abbaszadeh Sori

    2014-06-01

    Full Text Available DNA computers use strands of DNA to perform computing operations. The computer consists of two types of strands – the instruction strands and the input data strands. The instruction strands splice together the input data strands to generate the desired output data strand. DNA computing holds out the promise of important and significant connections between computers and living systems, as well as promising massively parallel computations. Before these promises are fulfilled, however, important challenges related to errors and practicality has to be addressed. On the other hand, new directions toward a synthesis of molecular evolution and DNA computing might circumvent the problems that have hindered development, so far. This paper represent present and future DNA computer.

  8. Hemangioblastoma presenting with intraparenchymatous hemorrhage.

    Science.gov (United States)

    Wakai, S; Inoh, S; Ueda, Y; Nagai, M

    1984-11-01

    The authors report six cases of hemangioblastoma presenting with apoplectic symptoms but with no history related to the tumor. In each case, computerized tomography disclosed an intraparenchymatous hemorrhage, which was located supratentorially in four and in the cerebellum in the remaining two. Angiography revealed an abnormal vascular blush in two cases, but no abnormal vessels or tumor blush in the other four. In all cases, a solid tumor with abnormal vessels, such as red veins and feeding arteries, was found within or adjacent to the hemorrhage at surgery. The possibility of hemangioblastoma should be kept in mind as a cause of intraparenchymatous hemorrhage, particularly subcortical. Evacuation of the hematoma should be carefully carried out, and the whole hematoma wall should be thoroughly investigated for abnormal vessels or a solid mass. PMID:6541682

  9. Intracerebral Hemorrhage. A Case Presentation

    Directory of Open Access Journals (Sweden)

    Idaylí Pérez Rodríguez

    2007-04-01

    Full Text Available A 70 year-old female patient suffering from a cerebrovascular disease intracerebral hemorrhage type and presented as Le Roux 2 cerebromeningeal hemorrhage subtype with factors for a bad prognosis of neurologic causes and, for diverse complications which evolved in the clinical intensive care service at the University hospital ¨Dr. Gustavo Aldereguia Lima¨ in Cienfuegos city. According to the management stated in the clinical practice guideline of the protocol intervention of this health institution an achievement was obtained when the patient passed from a Rankin 5 state at the admission of the hospital to a Rankin 3 state at the time of discharging from the institution. The survival rate at the time of the last evolution was a Rankin 2.

  10. [The present in the brain].

    Science.gov (United States)

    Murakami, Ikuya

    2013-08-01

    How is the present represented in the brain? This review introduces several theoretical and experimental issues regarding time perception, with special focus on the human visual system. Specifically, it addresses possible ways through which visual information can be processed to allow for the conscious experience of spatio-temporal local relations, object-based temporal localization, object duration, and mental time. We begin with a brief mention of isomorphism and its limitations, and from there we proceed to discuss low-level mechanisms for timing outer events. The concept of spatiotemporal receptive fields with biphasic temporal impulse response functions is introduced. Neurons with such receptive fields are believed to extract elementary information about spatial and temporal inclinations of light intensity. These visual primitives are later reconstructed in biologically meaningful ways to create each perceptual timeline in the brain. The precise mechanism by which each perceptual timeline is created remains unknown; however, for the purpose of this paper, we refer to it as "context", relative to which novel objects are to be spatiotemporally localized by using various cues. Localization involves estimation, including prediction and "postdiction" from currently available cues. As such, many aspects of the subjective present, such as "perceived timing", "subjective duration", and "mental clock" result from estimation and are thus prone to errors, leading often to time illusion. More than one perceptual timeline can exist and serve as an inner clock for multiple objects, multiple attributes, and even for multiple sensory modalities. Calibration across timelines is also a major issue; our ability to exercise flexible recalibration with short-term training or adaptation using salient time markers is briefly argued before ending the review. PMID:23917494

  11. Nuclear Fuels: Present and Future

    Directory of Open Access Journals (Sweden)

    Donald R. Olander

    2009-02-01

    Full Text Available The important new developments in nuclear fuels and their problems are reviewed and compared with the status of present light-water reactor fuels. The limitations of these fuels and the reactors they power are reviewed with respect to important recent concerns, namely provision of outlet coolant temperatures high enough for use in H2 production, destruction of plutonium to eliminate proliferation concerns, and burning of the minor actinides to reduce the waste repository heat load and long-term radiation hazard. In addition to current oxide-based fuel-rod designs, the hydride fuel with liquid metal thermal bonding of the fuel-cladding gap is covered. Finally, two of the most promising Generation IV reactor concepts, the Very High Temperature Reactor and the Sodium Fast Reactor, and the accompanying reprocessing technologies, aqueous-based UREX and pyrometallurgical, are summarized. In all of the topics covered, the thermodynamics involved in the material's behavior under irradiation and in the reprocessing schemes are emphasized.

  12. Source rock hydrocarbons. Present status

    International Nuclear Information System (INIS)

    This report first presents the characteristics of conventional oil and gas system, and the classification of liquid and gaseous non conventional hydrocarbons, with the peculiar case of coal-bed methane. The authors then describe how source rock hydrocarbons are produced: production of shale oils and gases (horizontal drilling, hydraulic fracturing, exploitation) and of coal-bed methane and coal mine methane. In the next part, they address and discuss the environmental impact of source rock hydrocarbon production: installation footprint, water resource management, drilling fluids, fracturing fluids composition, toxicity and recycling, air pollution, induced seismicity, pollutions from other exploitation and production activities. They propose an overview of the exploitation and production of source rock gas, coal-bed gas and other non conventional gases in the world. They describe the current development and discuss their economic impacts: world oil context and trends in the USA, in Canada and other countries, impacts on the North American market, on the world oil industry, on refining industries, on the world oil balance. They analyse the economic impacts of non conventional gases: development potential, stakes for the world gas trade, consequence for gas prices, development opportunities for oil companies and for the transport sector, impact on CO2 emissions, macro-economic impact in the case of the USA

  13. A cool present for LEIR

    CERN Multimedia

    2005-01-01

    LEIR (Low Energy Ion Ring), which will supply lead ions to the LHC experiments, has taken delivery of one of its key components, its electron cooling system. From left to right, Gérard Tranquille, Virginia Prieto and Roland Sautier, in charge of the electron cooling system for LEIR at CERN, and Christian Lacroix, in charge of installation for the LEIR machine. On 16 December, the day before CERN's annual closure, the LEIR teams received a rather impressive Christmas present. The "parcel" from Russia, measuring 7 metres in length and 4 metres in height, weighed no less than 20 tonnes! The component will, in fact, be one of the key elements of the future LEIR, namely its electron cooling system. LEIR is one of the links in the injector chain that will supply lead ions to the LHC experiments, in particular ALICE (see Bulletin No. 28/2004 of 5 July 2004), within the framework of the I-LHC Project. The electron cooling system is designed to reduce and standardise transverse ion velocity. This focuses the bea...

  14. Augmented reality: past, present, future

    Science.gov (United States)

    Inzerillo, Laura

    2013-03-01

    A great opportunity has permitted to carry out a cultural, historical, architectural and social research with great impact factor on the international cultural interest. We are talking about the realization of a museum whose the main theme is the visit and the discovery of a monument of great prestige: the monumental building the "Steri" in Palermo. The museum is divided into sub themes including the one above all, that has aroused the international interest so much that it has been presented the instance to include the museum in the cultural heritage of UNESCO. It is the realization of a museum path that regards the cells of the Inquisition, which are located just inside of some buildings of the monumental building. The project, as a whole, is faced, in a total view, between the various competences implicated: historic, chemic, architectonic, topographic, drawing, representation, virtual communication, informatics. The birth of the museum will be a sum of the results of all these disciplines involved. Methodology, implementation, fruition, virtual museum, goals, 2D graphic restitution, effects on the cultural heritage and landscape environmental, augmented reality, Surveying 2D and 3D, hi-touch screen, Photogrammetric survey, Photographic survey, representation, drawing 3D and more than this has been dealt with this research.

  15. Database Systems - Present and Future

    Directory of Open Access Journals (Sweden)

    2009-01-01

    Full Text Available The database systems have nowadays an increasingly important role in the knowledge-based society, in which computers have penetrated all fields of activity and the Internet tends to develop worldwide. In the current informatics context, the development of the applications with databases is the work of the specialists. Using databases, reach a database from various applications, and also some of related concepts, have become accessible to all categories of IT users. This paper aims to summarize the curricular area regarding the fundamental database systems issues, which are necessary in order to train specialists in economic informatics higher education. The database systems integrate and interfere with several informatics technologies and therefore are more difficult to understand and use. Thus, students should know already a set of minimum, mandatory concepts and their practical implementation: computer systems, programming techniques, programming languages, data structures. The article also presents the actual trends in the evolution of the database systems, in the context of economic informatics.

  16. [Premature newborn: a case presentation].

    Science.gov (United States)

    Pastor Rodríguez, Jesús David; Pastor Bravo, María Del Mar; López García, Visitación; Cotes Teruel, María Isabel; Mellado, Jesús Eulogio; Cárceles, José Jara

    2010-01-01

    A case is presented of a premature newborn of 27 weeks gestation and weighing 420 grams who was delivered as a result of a maternal pre-eclampsia and retarded intra-uterine growth. During the 125 days of hospitalisation, an individual care plan based on the Virginia Henderson model was devised and applied to both the child and her parents using NANDA diagnostics, interventions according to the NIC classification, and the expected results according to the NOC classification. The Marjory Gordon functional patterns were used for the initial assessment. By applying the pre-term newborn (PTNB) plan, all their needs were provided and were modified throughout the hospital stay, with new needs that were added to the established ones. These required a continuous assessment with the subsequent adapting of the care plan. Likewise, the care required by the parents varied from the initial grief due to the possible loss of their child to learning the alarm signs and the home care that their child would need. The child was finally discharged weighing 2900 grams and with normal neurological and psychomotor development, although with a lower weight appropriate to her age. Currently, at 2 years old, the child has a normal neurological and psychomotor development, but with weight and size lower than the P(3) percentile. She requires speech therapy treatment due to paralysis of the right vocal cord. PMID:20605104

  17. Presentation of the results 97

    International Nuclear Information System (INIS)

    Gaz de France (GDF) presents in a press kit the main results achieved in 1997. The European community has formulated a project of definition of rules concerning the natural gas market. Minima values for annual consumptions have been defined and the consumption and use of natural gas in EC countries is described. The financial results of GDF in 1997 are compared with previous years. Net sales grew by nearly 1 billion french francs to reach 55 billion. Overall sales were down by 4% but the share of natural gas in french energy consumption increased and sales to industrial users went up in particular due to new cogeneration plants installed in 1996. A comparison of gas prices in Europe is given for the years 1985 to 1998. The efforts of GDF to offer increased quality of services concerning in particular safety aspects as checking programs and installation of new safeguard appliances are described. The efforts of GDF to increase the energy market share of natural gas resulted in the development of new products like cogeneration, air conditioning and fuels for automotive needs. (C.B.)

  18. Ribavirin: Past, present and future

    Science.gov (United States)

    Loustaud-Ratti, Véronique; Debette-Gratien, Marilyne; Jacques, Jérémie; Alain, Sophie; Marquet, Pierre; Sautereau, Denis; Rousseau, Annick; Carrier, Paul

    2016-01-01

    Before the advent of direct acting antiviral agents (DAAs) ribavirin, associated to pegylated-interferon played a crucial role in the treatment of chronic hepatitis C, preventing relapses and breakthroughs. In the present era of new potent DAAs, a place is still devoted to the drug. Ribavirin associated with sofosbuvir alone is efficient in the treatment of most cases of G2 infected patients. All options currently available for the last difficult-to-treat cirrhotic G3 patients contain ribavirin. Reducing treatment duration to 12 wk in G1 or G4 cirrhotic compensated patients is feasible thanks to ribavirin. Retreating patients with acquired anti NS5A resistance-associated variants using ribavirin-based strategies could be useful. The addition of ribavirin with DAAs combinations however, leads to more frequent but mild adverse events especially in cirrhotic patients. Preliminary data with interferon-free second generation DAAs combinations without ribavirin suggest that future of the drug is jeopardized even in difficult-to-treat patients: The optimization of ribavirin dosage according to an early monitoring of blood levels has been suggested to be relevant in double therapy with peginterferon or sofosbuvir but not with very potent combinations of more than two DAAs. PMID:26807208

  19. Burning mouth syndrome: Present perspective

    Directory of Open Access Journals (Sweden)

    Ramesh Parajuli

    2015-07-01

    Full Text Available Introduction: Burning mouth syndrome is characterized by chronic oral pain or burning sensation affecting the oral mucosa in the absence of obvious visible mucosal lesions. Patient presenting with the burning mouth sensation or pain is frequently encountered in clinical practice which poses a challenge to the treating clinician. Its exact etiology remains unknown which probably has multifactorial origin. It often affects middle or old age women and it may be accompanied by xerostomia and altered taste. Objective: To review the current concepts regarding etiopathogenesis, diagnosis and management of this disorder. Methods and methodology: A literature review was conducted on PubMed/Medline and Google scholar about the burning mouth syndrome and the representative articles were selected and reviewed. Conclusion: There is no universal consensus regarding diagnosis, etiology and treatment of BMS. BMS is a diagnosis of exclusion which probably has multifactorial origin. Various pharmacological and non pharmacological treatments are available but it is difficult to achieve curative treatment so reassurance is of great importance while treating the patients. Combination of cognitive behavioral therapy, alpha lipoic acid and/or clonazepam has shown promising results.

  20. Clinical presentation of primary hypothyroidism

    International Nuclear Information System (INIS)

    Objective: To determine the clinical preparation of primary hypothyroidism at the time of diagnosis. Design: It was an observational and prospective study. Place and Duration of Study: Civil Hospital, Karachi from 1st January 1997 to 31st December 1997. Subjects and Methods: Forty-eight consecutive cases of primary hypothyroidism were included. A detailed history with special emphasis on symptoms and signs was conducted and the findings observed were noted in previously made proforma. Results: Primary hypothyroidism was found to be 5 times more common in female patients, with male to female ratio 1:5, majority of cases (33.33%) were between 41 to 50 years of age. The common symptoms at the time of presentation were tiredness (95.8%), weakness (91.6%), weight gain (85.4%), hoarseness of voice (83.3%), cold intolerance (77.0%) and constipation (75.0%) in patients. Physical signs observed were delayed relaxation of ankle jerk (93.7%), periorbital edema (83.3%), thick tongue (62.5%), goiter (50.0%), dry and coarse skin (47.9%) in patients. Serum, TSH, T4 and T3 were performed in all cases through immunoradiometric technique. Serum TSH was markedly elevated, with normal to reduced T4 and T3 levels in all cases. Conclusion: Primary hypothyroidism was found more common in female than male of the age group 41-50 years. Weakness, tiredness, hoarseness of voice and constipation were the common symptoms noted. The diagnosis is almost certain on clinical grounds if the patient happens to have delayed relaxation of ankle jerks and periorbital puffiness. (author)

  1. Big bang nucleosynthesis: Present status

    Science.gov (United States)

    Cyburt, Richard H.; Fields, Brian D.; Olive, Keith A.; Yeh, Tsung-Han

    2016-01-01

    Big bang nucleosynthesis (BBN) describes the production of the lightest nuclides via a dynamic interplay among the four fundamental forces during the first seconds of cosmic time. A brief overview of the essentials of this physics is given, and new calculations presented of light-element abundances through 6Li and 7Li, with updated nuclear reactions and uncertainties including those in the neutron lifetime. Fits are provided for these results as a function of baryon density and of the number of neutrino flavors Nν. Recent developments are reviewed in BBN, particularly new, precision Planck cosmic microwave background (CMB) measurements that now probe the baryon density, helium content, and the effective number of degrees of freedom Neff. These measurements allow for a tight test of BBN and cosmology using CMB data alone. Our likelihood analysis convolves the 2015 Planck data chains with our BBN output and observational data. Adding astronomical measurements of light elements strengthens the power of BBN. A new determination of the primordial helium abundance is included in our likelihood analysis. New D/H observations are now more precise than the corresponding theoretical predictions and are consistent with the standard model and the Planck baryon density. Moreover, D/H now provides a tight measurement of Nν when combined with the CMB baryon density and provides a 2 σ upper limit Nνdata. In contrast with D/H and 4He, 7Li predictions continue to disagree with observations, perhaps pointing to new physics. This paper concludes with a look at future directions including key nuclear reactions, astronomical observations, and theoretical issues.

  2. A Presentation of Spectacular Visualizations

    Science.gov (United States)

    Hasler, Fritz; Einaudi, Franco (Technical Monitor)

    2000-01-01

    The NASA/NOAA/AMS Earth Science Electronic Theater presents Earth science observations and visualizations in a historical perspective. Fly in from outer space to Florida and the KSC Visitor's Center. Go back to the early weather satellite images from the 1960s see them contrasted with the latest International global satellite weather movies including killer hurricanes and tornadic thunderstorms. See the latest spectacular images from NASA and the National Oceanic and Atmospheric Administration (NOAA) remote sensing missions like the Geostationary Operational Environmental Satellites (GOES), NOAA, Tropical Rainfall Measuring Mission (TRMM), SeaWiFS, Landsat7, and new Terra which will be visualized with state-of-the art tools. Shown in High Definition TV resolution (2048 x 768 pixels) are visualizations of hurricanes Lenny, Floyd, Georges, Mitch, Fran, and Linda. See visualizations featured on covers of magazines like Newsweek, TIME, National Geographic, Popular Science, and on National and International Network TV. New Digital Earth visualization tools allow us to roam and zoom through massive global images including a Landsat tour of the US, with drill-downs into major cities using one meter resolution spy-satellite technology from the Space Imaging IKONOS satellite. Spectacular new visualizations of the global atmosphere and oceans are shown. See massive dust storms sweeping across Africa. See ocean vortexes and currents that bring up the nutrients to feed tiny plankton and draw the fish, giant whales and fisherman. See the how the ocean blooms in response to these currents and El Nino/La Nina climate changes. The demonstration is interactively driven by a SGI Octane Graphics Supercomputer with dual CPUs, 5 Gigabytes of RAM and Terabyte disk using two projectors across the super sized Universe Theater panoramic screen.

  3. A Presentation of Spectracular Visualizations

    Science.gov (United States)

    Hasler, Fritz; Pierce, Hal; Einaudi, Franco (Technical Monitor)

    2000-01-01

    The NASA/NOAA/AMS Earth Science Electronic Theater presents Earth science observations and visualizations in a historical perspective. Fly in from outer space to Florida and the KSC Visitor's Center. Go back to the early weather satellite images from the 1960s see them contrasted with the latest International global satellite weather movies including killer hurricanes & tornadic thunderstorms. See the latest spectacular images from NASA and NOAA remote sensing missions like GOES, NOAA, TRMM, SeaWiFS, Landsat7, & new Terra which will be visualized with state-of-the art tools. Shown in High Definition TV resolution (2048 x 768 pixels) are visualizations of hurricanes Lenny, Floyd, Georges, Mitch, Fran and Linda. See visualizations featured on covers of magazines like Newsweek, TIME, National Geographic, Popular Science and on National & International Network TV. New Digital Earth visualization tools allow us to roam & zoom through massive global images including a Landsat tour of the US, with drill-downs into major cities using I m resolution spy-satellite technology from the Space Imaging IKONOS satellite. Spectacular new visualizations of the global atmosphere & oceans are shown. See massive dust storms sweeping across Africa. See ocean vortexes and currents that bring up the nutrients to feed tiny plankton and draw the fish, giant whales and fisherman. See the how the ocean blooms in response to these currents and El Nino/La Nina climate changes. The demonstration is interactively driven by a SGI Octane Graphics Supercomputer with dual CPUs, 5 Gigabytes of RAM and Terabyte disk using two projectors across the super sized Universe Theater panoramic screen.

  4. Past and present Aral Sea

    Science.gov (United States)

    Dukhovniy, Viktor; Stulina, Galina; Eshchanov, Odylbek

    2013-04-01

    The tragedy of disappearing of Aral Sea is well known to the World. Before and after collapse of Soviet Union, a huge quantity of scientific and popular editions described with grief the situation around the Aral Sea. After the NIS states became independent, World Bank, UNDP, UNEP in proper competition with each other had provided some assessment of the situation through presentation of some small and medium grants, but after 2000, the local population remained alone with own problems. Although on the eyes of the present generation a unique transformation of great water body into deserts took place, the global scientific community did not find forces and financing for real and detail investigation of the processes accompanying the Sea shrinking and land formation. We should acknowledge and give big respect to NATO, later to German Government that through GTZ (now GIZ) - German International Collaboration Agency - and GFZ (Potzdam) paid attention to this area of environment crisis and organized scientific and protective design in the so-called Priaralie - the territory around the drying Sea and delta of the two rivers - Amudarya and Syrdarya. Thank to this assistance, the local specialists in collaboration with limited a number of foreign scientists (N.Aladin, P.Zavialov, Joop de Schutter, Hans Wilps, Hedi Oberhansli) organized significant works for detail socioeconomic, ecological and hydrological assessment situation in Priaralie and on the Aral sea coast. On this base, Ministry of Agriculture and Water resources of Uzbekistan and State Committee of Water resources of Kazakhstan developed a plan of rehabilitation of Amudarya and Syrdarya deltas and started implementation of these projects. If Kazakh water authority moved ahead in wetland restoration faster, a forestation of delta and drying bed of Aral Sea got big success in Uzbek territory. 244 thousands hectares of saxsaul and tamarix were planted for protection of the Priaralie. By request of GTZ SIC, ICWC

  5. Draft Workshop Summary and Presentations

    International Nuclear Information System (INIS)

    the electricity market reform in the UK); Session 4: Nuclear regulation and safety (Regulation for new build and new comer countries and Fukushima Safety Action Plan; WANO's contribution to strengthen nuclear safety worldwide; Strengthening Good Practice within Nuclear Safety post Fukushima-Daiichi); Session 5: Key Message for the Road-map update (Outline current status of nuclear technology development and need for additional R and D to address increased safety requirements; Provide an updated vision for nuclear energy's role in a low carbon energy system; Identify barriers and actions needed to accelerate the development and deployment of nuclear technologies to meet the Road-map vision; Identify and share lessons learned and best practices in nuclear regulation, front and back end fuel cycle practices, construction and financing. This document brings together the available presentations (slides) given at this workshop: 1 - Road-map overview and role of nuclear in IEA scenarios (Cecilia Tam, IEA); 2 - The Direction Of The 2014 Nuclear Road-map (Ron Cameron, OECD/NEA); 3 - Technology development needs for nuclear energy, 1.a: Reactor technology (Henri Paillere, OECD/NEA); 4 - IEA/NEA Nuclear Technology Road-map Update (Beth Lisann, US-DoE); 5 - Update of the Nuclear Energy Technology Road-map - Nuclear Decommissioning (Andreas Ehlert, E-On); 6 - Overcoming barriers to nuclear build - other than financing (Veronique Decobert, Westinghouse); 7 - Development of the supply chain: relying on local industrial involvement (Didier Beutier, Areva); 8 - Training and capacity development needs (Jorma Aurela, Finnish Ministry of Employment and the Economy); 9 - Key conditions for successful Nuclear new build financing (Anne Crepin, Areva); 10 - Regulation for New Build and Newcomers, IAEA Nuclear Safety Action Plan (David Shropshire, IAEA); 11 - WANO's contribution to strengthen nuclear safety worldwide (Bjarne Noren, WANO); 12 - Strengthening Good Practice within Nuclear Safety

  6. A rare cause of infant facial paralysis: atypical teratoid rhabdoid tumour located in the cerebellopontine angle

    OpenAIRE

    Öztürk, Mehmet; Siğirci, Ahmet; Karadağ, Neşe

    2015-01-01

    Atypical teratoid rhabdoid tumour (ATRT) is a rare malignant tumour of the central nervous system with embryonal roots. The majority are seen in early childhood and location is often in the posterior fossa. Surgery, radiotherapy and chemotherapy are used in treatment. Knowledge of the localisation of the mass preoperatively is necessary for direction of the chemoradiotherapy and sufficient resection in surgery. Differentiation from other brain tumours is important because of poor prognosis an...

  7. Presentation of Database on Aims and Visions

    DEFF Research Database (Denmark)

    Lundgaard, Jacob

    2005-01-01

    This presentation presents a database on aims and visions regarding regional development and transport and infrastructure in the corridor from Oslo-Göteborg-Copenhagen-Berlin. The process, the developed methodology as well as the result of the database is presented.......This presentation presents a database on aims and visions regarding regional development and transport and infrastructure in the corridor from Oslo-Göteborg-Copenhagen-Berlin. The process, the developed methodology as well as the result of the database is presented....

  8. 36 CFR 251.97 - Oral presentation.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Oral presentation. 251.97... presentation. (a) Purpose. An oral presentation provides an additional opportunity for an appellant, and other..., emphasize, and/or clarify information related to an appeal. Oral presentations are to be conducted in...

  9. 12 CFR 1102.36 - Oral presentations.

    Science.gov (United States)

    2010-01-01

    ... Practice for Proceedings § 1102.36 Oral presentations. (a) In general. A party does not have a right to an oral presentation. Under this section, a party's request to make an oral presentation may be denied if such a denial is appropriate and reasonable under the circumstances. An oral presentation shall...

  10. Refined solvable presentations for polycyclic groups

    CERN Document Server

    Hartung, René

    2011-01-01

    We announce a new type of polycyclic presentations, so-called solvable presentations, for polycyclic groups. These presentations are obtained by refining a series of normal subgroups with abelian sections. These presentations can be described effectively by presentation maps which yield the basis data structure to define a polycyclic group in computer-algebra-systems like {\\scshape Gap} or {\\scshape Magma}. We study these presentation maps and, in particular, we obtain consistency criteria for them. This consistency check has been implemented in the computer-algebra-system {\\scshape Gap}. Our implementation demonstrates that our method for solvable presentations is usually faster than the general methods for infinite polycyclic groups.

  11. Anatomy of the superior petrosal veins and their exposure and management during petrous apex meningioma surgery using the lateral suboccipital retrosigmoid approach.

    Science.gov (United States)

    Matsushima, Toshio; Kawashima, Masatou; Inoue, Kohei; Matsushima, Ken

    2014-10-01

    During surgeries in the upper cerebellopontine angle (CPA), the superior petrosal veins (SPVs) often act as obstacles; and their sectioning sometimes causes serious complications. In this study, we introduced a classification system for the SPVs wherein their tributaries were classified into four groups on the basis of their courses and draining areas. We furthermore explained the detailed anatomy of the vein of the cerebellopontine fissure, which is the largest tributary. In surgeries of petrous apex meningioma, the knowledge of the displacement pattern of the vein is very helpful for avoiding major venous complications. Therefore, we elucidated its anatomical situation in relation to the original portion of the meningioma and the natural draining point of the vein into the superior petrosal sinus (SPS) in each patient. In addition, we described the methods and techniques used to expose and manage the vein of the cerebellopontine fissure during surgery using the lateral suboccipital retrosigmoid approach. Presenting two illustrative cases, we recommend that the initial exposure of the tumor should be performed through the infratentorial lateral supracerebellar route and that the suprafloccular cistern is the best area to find the vein of the cerebellopontine fissure. We emphasized the importance of the preservation of the vein of the cerebellopontine fissure and also proposed the order for exposure of SPV tributaries during upper CPA surgery using the retrosigmoid approach. PMID:24781190

  12. Alopecia as the Presenting Symptom of Syphilis.

    Science.gov (United States)

    Ornelas, Jennifer; Agbai, Oma N; Kiuru, Maija; Sivamani, Raja K

    2015-07-01

    Alopecia can be one of the many symptoms of secondary syphilis and the clinical presentations include essential syphilitic alopecia or symptomatic syphilitic alopecia. In this report, we present a case of a patient with essential syphilitic alopecia whose sole presenting symptom of syphilis was alopecia. Despite an initial negative rapid plasma reagin (RPR) test, he was ultimately found to have syphilis on scalp biopsy. His alopecia improved following treatment with benzathine penicillin. This presentation serves as a reminder to clinicians to be cognizant of alopecia as a presenting sign of syphilis. A review of the specificity and sensitivity of the typical tests used for the diagnosis is presented. PMID:26436969

  13. The Design Space of Information Presentation

    DEFF Research Database (Denmark)

    May, Michael; Petersen, Johannes

    2007-01-01

    A semiotic approach to the design space of information presentation is presented in which Formal Concept Analysis (FCA) is used to represent and explore attributes of abstract sign types and the media (graphical, haptic, acoustic, gestic) through which they are presented as specific representatio......A semiotic approach to the design space of information presentation is presented in which Formal Concept Analysis (FCA) is used to represent and explore attributes of abstract sign types and the media (graphical, haptic, acoustic, gestic) through which they are presented as specific...

  14. Present status of fission yield data

    International Nuclear Information System (INIS)

    Fission yield data of minor actinides are needed for transmutation of nuclear waste by an ADS system. The yield data, however, are not enough for the application. The present status of the yield data is presented in this report. (author)

  15. Presentation of SEPS, a.s

    International Nuclear Information System (INIS)

    In these video-movies are presented: Presentation of Slovak Electric Power Transmission System (SEPS); History of the transmission systems; Development of the transmission system; Slovak Power Dispatching; Diagnostic activities Krizovany

  16. Redundant Information Presentation in Hypertext Learning Environments

    NARCIS (Netherlands)

    Bezdan, Eniko; Kester, Liesbeth; Kirschner, Paul A.

    2011-01-01

    Bezdan, E., Kester, L., & Kirschner, P. A. (2011, 29 August). Redundant Information Presentation in Hypertext Learning Environments. Presentation at the pre-conference of the Junior Researchers of EARLI, Exeter, United Kingdom.

  17. Unusual Presentation of Cystic Papillary Thyroid Carcinoma

    OpenAIRE

    Patil, Vijayraj S.; Abhishek Vijayakumar; Neelamma Natikar

    2012-01-01

    Papillary thyroid carcinoma is the most common thyroid malignancy, accounting for 80% of all thyroid cancers. The most common presentation of thyroid cancer is an asymptomatic thyroid mass or a nodule. Usually as thyroid enlarges, it extends in to mediastinum. Papillary thyroid carcinoma presentation as multiple true cystic swelling extending from neck to anterior chest wall in subcutaneous plane is not present in the literature. We present a rare case of cystic papillary thyroid carcinoma wh...

  18. Presentation skills for the nurse educator.

    Science.gov (United States)

    Longo, Anne; Tierney, Carol

    2012-01-01

    With the increase in interdisciplinary bedside rounds, shared governance, and other leadership opportunities, nurses find themselves in positions requiring the creation and delivery of oral presentations. This is not a skill that comes naturally to most nurses and is often noted as the one leadership skill that causes the most personal discomfort. Today educators are in a position to coach inexperienced staff in developing their presentation skills. This article presents recommendations for designing and delivering winning presentations. PMID:22261901

  19. Left atrial myxoma presenting as pseudobulbar palsy.

    Directory of Open Access Journals (Sweden)

    Kumar A

    2002-04-01

    Full Text Available A case of left atrial (LA myxoma presenting as pseudobulbar palsy, due to multiple cerebral infarcts, without any cardiac manifestations, is presented. LA myxoma is rare cause of embolization to CNS causing ischemic infarcts. Due to multiple CNS infarcts patient can present with varied clinical picture and pseudobulbar palsy is not a very common presentation. It was a real diagnostic dilemma before LA myxoma was diagnosed on echocardiography.

  20. Refined solvable presentations for polycyclic groups

    Directory of Open Access Journals (Sweden)

    René Hartung

    2012-06-01

    Full Text Available We describe a new type of presentation that, when consistent, describes a polycyclic group. This presentation is obtained by re ning a series of normal subgroups with abelian sections. These presentations can be described e ectively in computeralgebra- systems like Gap or Magma. We study these presentations and, in particular, we obtain consistency criteria for them. The consistency implementation demonstrates that there are situations where the new method is faster than the existing methods for polycyclic groups.

  1. 7 CFR 2901.3 - Oral presentation.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Oral presentation. 2901.3 Section 2901.3 Agriculture... presentation. Any person seeking an adjustment under this part 2901 shall be given an opportunity to make an oral presentation of data, views and arguments in support of the request for an adjustment,...

  2. Do You Like Sending Presents Between Frends?

    Institute of Scientific and Technical Information of China (English)

    王秋元; 林达; Roy; 田田; Jenny

    2007-01-01

    王秋元Yes, I do. I think it is very important. When I get a present from a friend, I feel happy because it means that he or she cares about me. Different presents have different meanings. It doesn’t have to be expensive. It is important because it carries love. Do not forget to send presents to your friends.

  3. The Teacher as Researcher: Presenting Your Case.

    Science.gov (United States)

    Brumbaugh, Kenneth E; Poirot, James L.

    1993-01-01

    Discusses presentations as a format teachers can use for dissemination of research findings. The sixth in a series on the teacher as researcher, the article covers identifying the target audience; organizing and practicing a presentation; and choosing appropriate audio-video technologies. A sidebar provides a generalized presentation outline. (KRN)

  4. Scrub Typhus Presenting as Acute Mastoiditis

    Directory of Open Access Journals (Sweden)

    Bhushal Lal

    2014-02-01

    Full Text Available Scrub typhus, a zoonosis, is known to present with varied clinical presentation. We present a case of acute mastoiditis who did not respond to conventional antibiotic therapy. The detailed repeat clinical examination revealed lymphadenopathy with eschar and IgM antibodies for scrub typhus by ELISA were positive. Patient had dramatic response to doxycycline therapy.

  5. Scrub Typhus Presenting as Acute Mastoiditis

    OpenAIRE

    Bhushal Lal; Ravinder Singh Minhas; Dev Raj Sharma; Suresh Kumar

    2014-01-01

    Scrub typhus, a zoonosis, is known to present with varied clinical presentation. We present a case of acute mastoiditis who did not respond to conventional antibiotic therapy. The detailed repeat clinical examination revealed lymphadenopathy with eschar and IgM antibodies for scrub typhus by ELISA were positive. Patient had dramatic response to doxycycline therapy.

  6. Idiopathic cervical osteomyelitis presenting as dysphagia

    OpenAIRE

    Ghaly GA; Espeso A; Fish B

    2010-01-01

    We discuss a case of idiopathic cervical epidural abscess, complicated by osteomyelitis, presenting with dysphagia as the main complaint. No predisposing factors were identified and blood cultures were negative. Case was treated conservatively by long course of IV antibiotics. We present a review of presentation of spinal epidural abscesses and indications for surgical intervention.

  7. Effect of Notecard Restrictions on Student Presentations

    Science.gov (United States)

    Decker, Ronald; Tyler, Leon

    2013-01-01

    Student presentations are an integral part of many business course curricula. PowerPoint™ and other presentation slideware offerings create opportunities for students to create text laden slides which are used as Teleprompters by less than fully-prepared presenters. Numerous prescriptions have been proposed for remedying text laden presentation…

  8. Clinical presentation of adult coeliac disease.

    LENUS (Irish Health Repository)

    Tajuddin, T

    2012-02-01

    The mode of presentation of coeliac disease has been changing to more atypical or silent disease. Few studies described the clinical presentation of adult coeliac disease in Ireland in recent years. We retrospectively collected the clinical data for all patients who had a diagnosis of coeliac disease made in our centre between January 07 and December 08. Forty seven adults, predominantly females (n = 30), had a confirmed diagnosis of coeliac disease made during the study period. In our patient cohort, the presenting symptom was diarrhoea in 19 (40%) patients, while 16 patients (34%) did not have any G.I. symptoms, 10 (21%) presented with anaemia. Females presented at a significantly younger age compared to males, with median ages at diagnosis of 44.5 and 57 years, respectively (p = 0.04). Females also presented more commonly with non G.I. symptoms (p = 0.07). The reasons behind this gender difference need further study.

  9. Chromobacterium violaceum presenting as a surgical emergency

    International Nuclear Information System (INIS)

    A case of Chromobacterium violaceum infection in a patient who apparently acquired the infection from the water of a Florida river is described. In addition to the usual presentation of sepsis, hepatic abscesses, and pustular dermatits, the patient presented as an acute abdominal emergency. Although most reported cases have been fatal, this patient recovered completely. Chromobacterium violaceum infection should be considered when a patient presents with a febrile illness after a water accident in the southeastern United States

  10. Nasopharyngeal bursitis: from embryology to clinical presentation

    OpenAIRE

    AE El-Shazly; S Barriat; PP Lefebvre

    2010-01-01

    AE El-Shazly, S Barriat, PP LefebvreDepartment of Otorhinolaryngology and Head and Neck Surgery, Liege University Hospital, Liege, BelgiumAbstract: Nasopharyngeal bursitis is a relatively rare syndrome characterized by a collection of symptoms that multidisciplinary specialists should be aware of. Here we present an audit of cases presenting to a rhinology clinic over a two-year period, as well as an overview of the relevant embryology and different clinical presentations of nasopharyngeal bu...

  11. Multiple Dural Tuberculomas Presenting as Leptomeningeal Carcinomatosis

    OpenAIRE

    Ahmet Bekar; Ahmet Karaoğlu; Elif Başaran; Hasan Kocaeli; Özgür Taşkapılıoğlu

    2011-01-01

    Objective and Importance. We present the rare occurrence of multiple dural-based tuberculomas mimicking leptomeningeal carcinomatosis in a young immunocompetent patient. Clinical Presentation. A 36-year-old man presented with a 2-month history of generalized epileptic activity and altered perception. Neurological examination was remarkable for bilateral Babinski's sign. Cranial magnetic resonance imaging (MRI) revealed multiple dural-based enhancing lesions with cerebral edema. Intervention. ...

  12. Tests and present status of gauge theories

    International Nuclear Information System (INIS)

    The author discusses the predictions of the standard model for strong, weak and electromagnetic interactions. The Abelian Model is presented to represent gauge theories at work. Hadronic structure functions are explained which describe the distribution of quarks and gluons within the initial state hadrons. Hadronic fragmentation functions are defined and illustrated. A set of exercises is presented which may be helpful toward understanding the material presented

  13. Extramedullary leukemia in children presenting with proptosis

    OpenAIRE

    Naik Milind; Honavar Santosh G; Vemuganti Geeta K; Murthy Ramesh; Reddy Vijayanand

    2009-01-01

    Abstract Background We highlight the orbital manifestations of acute myeloid leukemia and the role of peripheral blood smear in the diagnosis of these cases. A total of 12 patients who presented with proptosis and were subsequently diagnosed to have acute myeloid leukemia based on incision biopsy or peripheral blood smear were included in the study. Results A retrospective review of all cases of acute myeloid leukemia presenting to the Orbital clinic was performed. The age at presentation, ge...

  14. Presentation of Ileal Burkitt Lymphoma in Children

    OpenAIRE

    Grajo, Joseph R; Kayton, Mark L.; Steffensen, Thora S.; Dragicevic, Natasa; Guidi, Claude B.

    2012-01-01

    Burkitt lymphoma is a highly aggressive form of Non-Hodgkin lymphoma that responds favorably if diagnosed accurately and treated early. Recognition of the various radiologic manifestations of Burkitt lymphoma can help guide the clinician to expedite appropriate chemotherapy. We present two cases that illustrate different radiologic presentations of this aggressive gastrointestinal malignancy in children. Case 1 features a 7-year-old boy who presented to our hospital with recurrent ileocecal i...

  15. An Unusual Presentation of Galactosemia: Hemophagocytic Lymphohistiocytosis

    OpenAIRE

    Ahmet Afşin Kundak; Ayşegül Zenciroğlu; Neşe Yaralı; Belma Saygılı Karagöl; Arzu Dursun; Selim Gökçe; Nilgün Karadağ; Nurullah Okumuş

    2012-01-01

    Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening condition. Uncontrolled proliferation of activated lymphocytes secreting high amounts of inflammatory cytokines seems to be the main pathogenesis. The diagnosis of HLH can often be difficult. It may presents in many forms such as fever of unknown origin, hepatitis, acute liver failure, and sepsis-like illness. Here we present a newborn galactosemia case presented with HLH. Close monitoring of the diagnostic criteria of HLH du...

  16. Paediatric presentation of type 2 neurofibromatosis

    OpenAIRE

    Evans, D.; Birch, J.; Ramsden, R

    1999-01-01

    BACKGROUND—Neurofibromatosis type 2 (NF2) is a highly penetrant autosomal dominant condition predisposing affected individuals to schwannomas and meningiomas. The proportion of children presenting with meningioma or schwannoma who have NF2 is not well described, and neither is the mode of presentation in most children with the inherited disease.
AIMS—To determine the frequency of childhood meningioma and schwannoma cases caused by NF2 and the mode of presentation.
METHODS...

  17. Trismus: An unusual presentation following road accident

    Directory of Open Access Journals (Sweden)

    Thakur Jagdeep

    2007-01-01

    Full Text Available Trismus due to trauma usually follows road accidents leading to massive faciomaxillary injury. In the literature there is no report of a foreign body causing trismus following a road accident, this rare case is an exception. We present a case of isolated presentation of trismus following a road accident. This case report stresses on the thorough evaluation of patients presenting with trismus following a road accident.

  18. Primary synovial osteochondromatosis presenting as constrictive capsulitis

    International Nuclear Information System (INIS)

    Primary synovial chondromatosis of the joints can present as capsular constriction with peri-articular osteopenia. This rare presentation is highlighted in three cases (two hips and one shoulder). The diagnosis in all the patients was made on arthrography and/or MRI/CT and was confirmed histologically. Synovial chondromatosis should be considered in patients with this presentation. Arthrography is the best imaging modality to confirm the cause (synovial chondromatosis) and effect (constrictive capsulitis). (orig.)

  19. Alopecia as the Presenting Symptom of Syphilis

    OpenAIRE

    Ornelas, Jennifer; Agbai, Oma N; Kiuru, Maija; Sivamani, Raja K.

    2015-01-01

    Alopecia can be one of the many symptoms of secondary syphilis and the clinical presentations include essential syphilitic alopecia or symptomatic syphilitic alopecia. In this report, we present a case of a patient with essential syphilitic alopecia whose sole presenting symptom of syphilis was alopecia. Despite an initial negative rapid plasma reagin (RPR) test, he was ultimately found to have syphilis on scalp biopsy. His alopecia improved following treatment with benzathine penicillin. Thi...

  20. Polyarteritis nodosa presenting with frank hematuria

    OpenAIRE

    Ahmad, Muhammad Shabi; Saha, Aninda; Reaich, David; Naisby, Geoffery P.; West, Alaiyi Fred

    2010-01-01

    Polyarteritis nodosa (PAN) is an uncommon systemic vasculitis characterized by necrotizing inflammation of small- or medium-sized arteries. The disease normally presents with non-specific symptoms. Urological symptoms at presentation are extremely rare. We report a 65-year-old man who was diagnosed with a polyarteritis nodosa having presented atypically with left testicular pain and swelling, and an intratesticular lesion. He developed painless visible hematuria while under investigation. No ...

  1. Subacute sclerosing panencephalitis presenting as mania

    Directory of Open Access Journals (Sweden)

    Aggarwal Ashish

    2011-01-01

    Full Text Available Subacute sclerosing panencephalitis (SSPE is a rare, invariably fatal degenerative disease of the central nervous system developing after measles infection. Besides neurological symptoms as initial presenting symptoms, rare reports of its presentation with pure psychiatric symptoms have been reported. We here report a case of 14 year old male who initially presented with manic symptoms and then subsequently diagnosed to be suffering from SSPE. Improtance of ruling our organic conditions is emphasized.

  2. Severe neuropsychiatric presentation of Wilson's disease

    OpenAIRE

    Chakor, Rahul T.; Santhosh, N. S.

    2011-01-01

    Wilson's disease (WD) is a relatively rare disease of copper metabolism. The diagnosis is often missed initially. The presentation is usually neurologic or hepatic, seen in 40% of patients. Psychiatric presentation of WD is reported in only 15% of patients. We present a 32-year-old patient with severe psychiatric manifestations. On examination, he had mild rest and postural tremors and a KF ring was seen. Serum ceruloplasmin was low and 24-hour urinary copper was elevated. The patient respond...

  3. Selected Regional Judicial Officer Cases, 2005 - Present

    Data.gov (United States)

    U.S. Environmental Protection Agency — This dataset contains selected cases involving EPA's Regional Judicial Officers (RJOs) from 2005 to present. EPA's Regional Judicial Officers (RJOs) perform...

  4. Take Presentations into the EFL Classroom

    Institute of Scientific and Technical Information of China (English)

    丁竞

    2014-01-01

    Presentations are activities in which people show, describe, or explain something to a group of people. They are often used in American school classrooms. On the base of the author’s referring to literature, observing classes and co-teaching prac-tice, presentations are suggested to be applied to EFL classrooms to help students improve their speaking levels and integrate their language skills efficiently. In point of ways of organizing, presentations can be divided into three types: controlled, guided and free ones. While in point of ways of applying, they can be divided into five types:interactive, role-plays, interview, note-taking, and discourse analysis ones. Thus different types of presentations should be adopted according to EFL students ’different levels and different communication purposes. Topics relating to EFL students’study, life and interest are practical for presentations. Im-portant aspects of presentations include: posture and presence, eye contact with the audience, volume and voice projection, rate of speech, use of audiovisual aids, vitality, adherence to the topic, keeping track of time, natural delivery, fluency and accuracy, the quantity of information presented, the way the topic was handled and how the questions are handled in the post-presentation session and so on. Presentation evaluations can be done by the teacher or together with student peers.

  5. Visual communication in presentation on physics

    Science.gov (United States)

    Grebenyuk, Konstantin A.

    2005-06-01

    It is essential that our audience be attentive during lecture, report or another presentation on physics. Therefore we have to take care of both speech and visual communication with audience. Three important aspects of successful visual aids use are singled out in this paper. The main idea is that physicists could appreciably increase efficiency of their presentations by use of these simple principles of presentation art. Recommendations offered are results of special literature research, author' s observations and experience of communication with skilled masters of presentations.

  6. Tafoni – presenting characteristics of a landform

    Directory of Open Access Journals (Sweden)

    Leni Ozis

    2014-12-01

    Full Text Available Landforms tafoni and alveoli – shallow caverns formed in boulders and rock faces – are presented in the article, with greater emphasis given on tafoni. Tafoni occur in different climate and rocks types, they are formed by cavernous weathering. In Slovenian geographical literature term tafoni rarely occurs. Exceptions are some examples of describing tafoni as landforms that are similar to another landform – rock shelters. The aim of this article is to present main characteristics of tafoni, introduce some terms that are being related to tafoni, present dilemmas related to existing knowledge of tafoni, and present tafoni’s features that are different from that of rock shelters.

  7. Dengue infection presenting as acute hypokalemic quadriparesis

    Directory of Open Access Journals (Sweden)

    N Gupta

    2014-01-01

    Full Text Available Dengue infection is one of the most common viral hemorrhagic fevers seen in the tropical countries, including India. Its presentation varies from an acute self-resolving febrile illness to life-threatening hemorrhagic shock and multiorgan dysfunction leading to death. Neurological presentations are uncommon and limited to case reports only. Most common neurological manifestations being encephalitis, acute inflammatory demyelinating polyradiculoneuropathy, transverse myelitis, and acute disseminated encephalomyelitis.Hypokalemic quadriparesis as a presenting feature of dengue is extremely rare. Here, we report this case of a 33-year-old female, who presented with hypokalemic quadriparesis and was subsequently diagnosed as dengue infection.

  8. Prolactinoma presenting with intermittent third nerve palsy.

    OpenAIRE

    Wykes, W N

    1986-01-01

    A patient presented with a painful third nerve palsy. This resolved spontaneously, but recurred several months later. At his second presentation carotid angiography gave normal results, but a high resolution CT scan showed a tumour in the right parasellar region. The serum prolactin was raised at over 22,000 millimicrons/, showing this to be a prolactinoma.

  9. Hartnup disease presenting in an adult.

    Science.gov (United States)

    Oakley, A; Wallace, J

    1994-09-01

    A young woman presented with pellagra. Her symptoms were precipitated by prolonged lactation and increased activity. Dietary intake of niacin was within recommended guidelines. Chromatography of urinary amino acids was diagnostic of Hartnup disease, an inherited disorder usually presenting in childhood. Her symptoms resolved with oral nicotinamide. PMID:7955499

  10. Identities among relations of group presentations

    International Nuclear Information System (INIS)

    The aim of this article is to give an account of the theory of (identity) sequences over group presentations. In the first section the algebraic theory is discussed, in the next one an elementary and complete exposition of the theory of pictures is given and some examples of so-called combinatorially aspherical presentations are discussed in the last section. 62 refs

  11. Presentation Trainer Prototype 2.0

    NARCIS (Netherlands)

    Schneider, Jan; Börner, Dirk

    2014-01-01

    It is a tool to train nonverbal communication skills for presentations. It was the first tested version of the Presentation Trainer for the PhD project on sensor-based learning support. It includes the first dashboard design of the trainer. Available under the GNU LGPL licence version 3 or higher.

  12. Permutation presentations of modules over finite groups

    OpenAIRE

    Katsura, Takeshi

    2006-01-01

    We introduce a notion of permutation presentations of modules over finite groups, and completely determine finite groups over which every module has a permutation presentation. To get this result, we prove that every coflasque module over a cyclic p-group is permutation projective.

  13. Glossopharyngeal schwannoma presenting as gagging dysphagia.

    OpenAIRE

    Tay, H.L.; Swanston, A. R.; Lumley, J. S.

    1994-01-01

    A case of cervical glossopharyngeal schwannoma presenting with gagging dysphagia is presented. Treatment was by total excision of the schwannoma following which the patient made a good recovery. To our knowledge, this is the first report of gagging dysphagia associated with a glossopharyngeal schwannoma.

  14. Retroperitoneal synovial sarcoma presenting as paraneoplastic hypoglycaemia

    Directory of Open Access Journals (Sweden)

    Reddy VV

    2015-01-01

    Full Text Available Synovial sarcoma is a well-recognized malignant mesenchymal neoplasm. Primary retroperitoneal synovial sarcoma is extremely rare and has poor prognosis. There are sparse reports in the literature on the secretory synovial sarcomas. In this report, we present the case of a patient with retroperitoneal synovial sarcoma who presented with recurrent attacks of hypoglycaemia.

  15. Retroperitoneal synovial sarcoma presenting as paraneoplastic hypoglycaemia

    OpenAIRE

    Reddy VV; Sarala S; Mathai V; Madhu; Sreedhar Babu KV

    2015-01-01

    Synovial sarcoma is a well-recognized malignant mesenchymal neoplasm. Primary retroperitoneal synovial sarcoma is extremely rare and has poor prognosis. There are sparse reports in the literature on the secretory synovial sarcomas. In this report, we present the case of a patient with retroperitoneal synovial sarcoma who presented with recurrent attacks of hypoglycaemia.

  16. 19 CFR 112.47 - Wrongful presentation.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Wrongful presentation. 112.47 Section 112.47 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CARRIERS, CARTMEN, AND LIGHTERMEN Identification Cards § 112.47 Wrongful presentation. If...

  17. Evaluating Presentation Skills of Volunteer Trainers.

    Science.gov (United States)

    Mohan, Donna K.

    A systematic method for evaluating the presentation skills of volunteer trainers would enable the discovery of hidden problems. It would also increase individual trainer skills and satisfaction and improve the overall effectiveness of the training program. A first step is to determine the general presentation skills a successful volunteer trainer…

  18. Renal Cell Carcinoma Presenting as Dysphagia

    OpenAIRE

    Chauhan, Sharad; Yadav, Sher Singh; Tomar, Vinay

    2015-01-01

    Renal cell carcinoma presenting with dysphagia is rare. We report a case who presented with dysphagia as the only manifestations of renal malignancy. Biopsy from the pyriform fossa nodules revealed a clear cell neoplasm. Immuno-histochemical analysis of tissue confirmed metastasis of renal cell carcinoma.

  19. Considering the Audience: Air Force Recruiting Presentations

    Science.gov (United States)

    Malone, Darek L.

    2012-01-01

    Each Air Force recruiter is formally trained in public speaking and the art of salesmanship or persuasion. These recruiters communicate to thousands of high school students each year through presentations in classrooms, auditoriums and other venues as part of their assigned duties. Persuasive presentations are public speaking events specifically…

  20. Computer programmes for mineral processing presentation

    OpenAIRE

    Krstev, Aleksandar; Krstev, Boris; Golomeov, Blagoj; Golomeova, Mirjana

    2009-01-01

    In this paper will be shown computer application of softwares Minteh-5, Minteh-6 and Cyclone in Visual Basic, Visual Studio for presentation of two-products for some closed circuits od grinding-clasifying processes. These methods make possibilities for appropriate, fast and sure presentation of some complex circuits in the mineral processing technologies.