WorldWideScience

Sample records for centrifuge system sisak-3

  1. Studies on the chemistry of element 104 with the centrifuge system SISAK-3

    Energy Technology Data Exchange (ETDEWEB)

    Eberhardt, K.; Kratz, J.V.; Mendel, M.; Naehler, A.; Trautmann, N.; Wiehl, N. [Mainz Univ. (Germany); Alstadt, J.; Omtvedt, J.P. [Oslo Univ. (Norway); Malmbeck, R.; Skarnemark, G.; Wierczinski, B. [Chalmers Univ. of Technology, Goeteborg (Sweden); Eichler, B.; Gaeggeler, H.W.; Jost, D.T.; Tuerler, A. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1997-09-01

    The centrifuge system SISAK-3 combined with a detector for the measurement of {alpha}-particles and spontaneous fission (SF) fragments in a flowing organic liquid has been applied to study the chemical behaviour of element 104 produced in the reaction {sup 248}Cm({sup 18}O,5n){sup 261}104. (author) 2 figs., 2 refs.

  2. Centrifugal unbalance detection system

    Science.gov (United States)

    Cordaro, Joseph V.; Reeves, George; Mets, Michael

    2002-01-01

    A system consisting of an accelerometer sensor attached to a centrifuge enclosure for sensing vibrations and outputting a signal in the form of a sine wave with an amplitude and frequency that is passed through a pre-amp to convert it to a voltage signal, a low pass filter for removing extraneous noise, an A/D converter and a processor and algorithm for operating on the signal, whereby the algorithm interprets the amplitude and frequency associated with the signal and once an amplitude threshold has been exceeded the algorithm begins to count cycles during a predetermined time period and if a given number of complete cycles exceeds the frequency threshold during the predetermined time period, the system shuts down the centrifuge.

  3. Centrifugal shot blast system

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-02-01

    This report describes a demonstration of Concrete cleaning, Inc., modified centrifugal shot blast technology to remove the paint coating from concrete flooring. This demonstration is part of the Chicago Pile-5 (CP-5) Large-Scale Demonstration Project (LSDP) sponsored by the US Department of Energy (DOE), office of Science and Technology (OST), Deactivation and Decommissioning Focus Area (DDFA). The objective of the LSDP is to select and demonstrate potentially beneficial technologies at the Argonne National Laboratory-East (ANL) CP-5 Research Reactor. The purpose of the LSDP is to demonstrate that using innovative and improved decontamination and decommissioning (D and D) technologies from various sources can result in significant benefits, such as decreased cost and increased health and safety, as compared with baseline D and D technologies. Potential markets exist for the innovative centrifugal shot blast system at the following sites: Fernald Environmental Management Project, Los Alamos, Nevada, Oak Ridge Y-12 and K-25, Paducah, Portsmouth Gaseous Diffusion site, and the Savannah River Site. This information is based on a revision to the OST Linkage Tables dated August 4, 1997.

  4. Centrifugal shot blast system

    International Nuclear Information System (INIS)

    This report describes a demonstration of Concrete cleaning, Inc., modified centrifugal shot blast technology to remove the paint coating from concrete flooring. This demonstration is part of the Chicago Pile-5 (CP-5) Large-Scale Demonstration Project (LSDP) sponsored by the US Department of Energy (DOE), office of Science and Technology (OST), Deactivation and Decommissioning Focus Area (DDFA). The objective of the LSDP is to select and demonstrate potentially beneficial technologies at the Argonne National Laboratory-East (ANL) CP-5 Research Reactor. The purpose of the LSDP is to demonstrate that using innovative and improved decontamination and decommissioning (D and D) technologies from various sources can result in significant benefits, such as decreased cost and increased health and safety, as compared with baseline D and D technologies. Potential markets exist for the innovative centrifugal shot blast system at the following sites: Fernald Environmental Management Project, Los Alamos, Nevada, Oak Ridge Y-12 and K-25, Paducah, Portsmouth Gaseous Diffusion site, and the Savannah River Site. This information is based on a revision to the OST Linkage Tables dated August 4, 1997

  5. Centrifugal separator devices, systems and related methods

    Science.gov (United States)

    Meikrantz, David H.; Law, Jack D.; Garn, Troy G.; Todd, Terry A.; Macaluso, Lawrence L.

    2012-03-20

    Centrifugal separator devices, systems and related methods are described. More particularly, fluid transfer connections for a centrifugal separator system having support assemblies with a movable member coupled to a connection tube and coupled to a fixed member, such that the movable member is constrained to movement along a fixed path relative to the fixed member are described. Also, centrifugal separator systems including such fluid transfer connections are described. Additionally, methods of installing, removing and/or replacing centrifugal separators from centrifugal separator systems are described.

  6. Compact, Automated Centrifugal Slide-Staining System

    Science.gov (United States)

    Feeback, Daniel L.; Clarke, Mark S. F.

    2004-01-01

    The Directional Acceleration Vector-Driven Displacement of Fluids (DAVD-DOF) system, under development at the time of reporting the information for this article, would be a relatively compact, automated, centrifugally actuated system for staining blood smears and other microbiological samples on glass microscope slides in either a microgravitational or a normal Earth gravitational environment. The DAVD-DOF concept is a successor to the centrifuge-operated slide stainer (COSS) concept, which was reported in Slide-Staining System for Microgravity or Gravity (MSC-22949), NASA Tech Briefs, Vol. 25, No. 1 (January, 2001), page 64. The COSS includes reservoirs and a staining chamber that contains a microscope slide to which a biological sample is affixed. The staining chamber is sequentially filled with and drained of staining and related liquids from the reservoirs by use of a weighted plunger to force liquid from one reservoir to another at a constant level of hypergravity maintained in a standard swing-bucket centrifuge. In the DAVD-DOF system, a staining chamber containing a sample would also be sequentially filled and emptied, but with important differences. Instead of a simple microscope slide, one would use a special microscope slide on which would be fabricated a network of very small reservoirs and narrow channels connected to a staining chamber (see figure). Unlike in the COSS, displacement of liquid would be effected by use of the weight of the liquid itself, rather than the weight of a plunger.

  7. ELECTRO-HYDRAULIC SERVO SYSTEM IN THE CENTRIFUGE FIELD

    Institute of Scientific and Technical Information of China (English)

    Dong Longlei; Yan Guirong; Li Ronglin

    2004-01-01

    The mechanical characteristics of the electro-hydraulic servo system in the centrifuge field are analyzed.The hydraulic pressure law in the centrifuge field indicates the existence of the centrifuge hydraulic pressure.The mechanical characteristics of the slide-valve and the dual nozzle flapper valve are studied,and it is found that the centrifuge field can not only increase the driving force or moment of the function units,but also decrease the stability of the components.Finally by applying Gauss minimum constraint principle,the dynamic model of the electro-hydraulic vibrator in the centrifuge field is established,and the mechanical restriction of the system is also presented.The study will be helpful for the realization of the combined vibration and centrifuge test system.

  8. Control system modeling of a centrifuge

    International Nuclear Information System (INIS)

    Improved control of a centrifuge can be achieved by using a mathematical model. This model is a linear, time-invariant, second order model which relates the input to the output of the centrifuge. After the Z-transform of the model was taken, a digital computer program was written to implement the model. The model parameters were optimized through correlation of the theoretical output as compared with the actual output of the centrifuge. As a result, a model was developed that simulated the centrifuge. Traditionally, a desired centrifuge output was produced by an input which was determined by trial and error. However, using the model with the desired output curve, the necessary input can be calculated with the digital computer program

  9. Separation of Nanoparticles in Aqueous Multiphase Systems through Centrifugation

    KAUST Repository

    Akbulut, Ozge

    2012-08-08

    This paper demonstrates the use of aqueous multiphase systems (MuPSs) as media for rate-zonal centrifugation to separate nanoparticles of different shapes and sizes. The properties of MuPSs do not change with time or during centrifugation; this stability facilitates sample collection after separation. A three-phase system demonstrates the separation of the reaction products (nanorods, nanospheres, and large particles) of a synthesis of gold nanorods, and enriches the nanorods from 48 to 99% in less than ten minutes using a benchtop centrifuge. © 2012 American Chemical Society.

  10. Bond graph modeling of centrifugal compression systems

    OpenAIRE

    Uddin, Nur; Gravdahl, Jan Tommy

    2015-01-01

    A novel approach to model unsteady fluid dynamics in a compressor network by using a bond graph is presented. The model is intended in particular for compressor control system development. First, we develop a bond graph model of a single compression system. Bond graph modeling offers a different perspective to previous work by modeling the compression system based on energy flow instead of fluid dynamics. Analyzing the bond graph model explains the energy flow during compressor surge. Two pri...

  11. Analysis of cantilever NEMS in centrifugal-fluidic systems

    Science.gov (United States)

    Mohsen-Nia, Mohsen; Abadian, Fateme; Abadian, Naeime; Dehkordi, Keivan Mosaiebi; Keivani, Maryam; Abadyan, Mohamadreza

    2016-07-01

    Electromechanical nanocantilevers are promising for using as sensors/detectors in centrifugal-fluidic systems. For this application, the presence of angular speed and electrolyte environment should be considered in the theoretical analysis. Herein, the pull-in instability of the nanocantilever incorporating the effects of angular velocity and liquid media is investigated using a size-dependent continuum theory. Using d’Alembert principle, the angular speed is transformed into an equivalent centrifugal force. The electrochemical and dispersion forces are incorporated considering the corrections due to the presence of electrolyte media. Two different approaches, i.e., the Rayleigh-Ritz method (RRM) and proposing a lumped parameter model (LPM), were applied to analyze the system. The models are validated with the results presented in literature. Impacts of the angular velocity, electrolyte media, dispersion forces, and size effect on the instability characteristics of the nanocantilever are discussed.

  12. Dynamical System Analysis of Unsteady Phenomena in Centrifugal Compressor

    Institute of Scientific and Technical Information of China (English)

    YasuyukiKomatsubara; ShimpeiMizuki

    1997-01-01

    Surge and rotating stall occurring in a centrifugal compressor system are investigated by using a phase portrait reconstruction method.From experimentally measured time series of data,the method clarified the cyclic behavior of surge.For rotating stall,there still remain problems in the phase portrait due to the chaotic behavior.However,the results obtained by the present method are able to provide new insights to the modelings for surge and rotating stall.Surge and roatting stall occurring in a centrifugal compressor system are investigated by using a phase portrait reconstruction method.From experimentally measured time series of data,the method clarified the cylcic behavior of surge.For rotating stall,there still remain problems in the phase portrait due to the chaotic behavior.However,the results obtained by the present method are able to provide new insights to the modelings for surge and rotating stall.

  13. Dynamical system analysis of unstable flow phenomena in centrifugal blower

    Directory of Open Access Journals (Sweden)

    Garcia David

    2015-09-01

    Full Text Available Methods of dynamical system analysis were employed to analyze unsteady phenomena in a centrifugal blower. Pressure signals gathered at different control points were decomposed into their Principal Components (PCs by means of Singular Spectrum Analysis (SSA. Certain number of PCs was considered in the analysis based on their statistical correlation. Projection of the original signal onto its PCs allowed to draw the phase trajectory that clearly separated non-stable blower working conditions from its regular operation.

  14. A centrifuge CO2 pellet cleaning system

    Science.gov (United States)

    Foster, C. A.; Fisher, P. W.; Nelson, W. D.; Schechter, D. E.

    1995-01-01

    An advanced turbine/CO2 pellet accelerator is being evaluated as a depaint technology at Oak Ridge National Laboratory (ORNL). The program, sponsored by Warner Robins Air Logistics Center (ALC), Robins Air Force Base, Georgia, has developed a robot-compatible apparatus that efficiently accelerates pellets of dry ice with a high-speed rotating wheel. In comparison to the more conventional compressed air 'sandblast' pellet accelerators, the turbine system can achieve higher pellet speeds, has precise speed control, and is more than ten times as efficient. A preliminary study of the apparatus as a depaint technology has been undertaken. Depaint rates of military epoxy/urethane paint systems on 2024 and 7075 aluminum panels as a function of pellet speed and throughput have been measured. In addition, methods of enhancing the strip rate by combining infra-red heat lamps with pellet blasting and by combining the use of environmentally benign solvents with the pellet blasting have also been studied. The design and operation of the apparatus will be discussed along with data obtained from the depaint studies.

  15. Transient analysis of charging system with centrifugal charging pumps

    International Nuclear Information System (INIS)

    The CARD (CVCS Analysis for Design) code has been developed for the transient analysis of the letdown and charging system of Korea Standard Nuclear Power Plant. The computer code has been already verified and validated by comparing with actual test results. Analyzed in this paper are the flow and pressure transients in the charging line. The sensitivity studies are performed to select the acceptable control parameters of charging line backpressure controller and seal injection flow controller. In addition, the seal injection system transient is evaluated for the pressurizer auxiliary spray operation. It is shown that the charging line backpressure controller control parameters yield a significant effect on the charging system stability. The results obtained from this study will be used to verify the system design and to select the optimum control parameters for the charging system with centrifugal charging pumps

  16. Experiments on Plasma Injection into a Centrifugally Confined System

    Science.gov (United States)

    Messer, S.; Bomgardner, R.; Brockington, S.; Case, A.; Witherspoon, F. D.; Uzun-Kaymak, I.; Elton, R.; Young, W.; Teodorescu, C.; Morales, C. H.; Ellis, R. F.

    2009-11-01

    We describe the cross-field injection of plasma into a centrifugally-confined system. Two different types of plasma railgun have been installed on the Maryland Centrifugal Experiment (MCX) in an attempt to drive that plasma's rotation. The initial gun was a coaxial device designed to mitigate the blowby instability. The second one was a MiniRailgun with a rectangular bore oriented so that the MCX magnetic field augments the railgun's internal magnetic field. Tests at HyperV indicate this MiniRailgun reaches much higher densities than the original gun, although muzzle velocity is slightly reduced. We discuss the impact of these guns on MCX for various conditions. Initial results show that even for a 2 kG field, firing the MiniRailgun modifies oscillations of the MCX diamagnetic loops and can impact the core current and voltage. The gun also has a noticeable impact on MCX microwave emissions. These observations suggest plasma enters the MCX system. We also compare diagnostic data collected separately from MCX for these and other guns, focussing primarily on magnetic measurements.

  17. High Technology Centrifugal Compressor for Commercial Air Conditioning Systems

    Energy Technology Data Exchange (ETDEWEB)

    Ruckes, John

    2006-04-15

    R&D Dynamics, Bloomfield, CT in partnership with the State of Connecticut has been developing a high technology, oil-free, energy-efficient centrifugal compressor called CENVA for commercial air conditioning systems under a program funded by the US Department of Energy. The CENVA compressor applies the foil bearing technology used in all modern aircraft, civil and military, air conditioning systems. The CENVA compressor will enhance the efficiency of water and air cooled chillers, packaged roof top units, and other air conditioning systems by providing an 18% reduction in energy consumption in the unit capacity range of 25 to 350 tons of refrigeration The technical approach for CENVA involved the design and development of a high-speed, oil-free foil gas bearing-supported two-stage centrifugal compressor, CENVA encompassed the following high technologies, which are not currently utilized in commercial air conditioning systems: Foil gas bearings operating in HFC-134a; Efficient centrifugal impellers and diffusers; High speed motors and drives; and System integration of above technologies. Extensive design, development and testing efforts were carried out. Significant accomplishments achieved under this program are: (1) A total of 26 builds and over 200 tests were successfully completed with successively improved designs; (2) Use of foil gas bearings in refrigerant R134a was successfully proven; (3) A high speed, high power permanent magnet motor was developed; (4) An encoder was used for signal feedback between motor and controller. Due to temperature limitations of the encoder, the compressor could not operate at higher speed and in turn at higher pressure. In order to alleviate this problem a unique sensorless controller was developed; (5) This controller has successfully been tested as stand alone; however, it has not yet been integrated and tested as a system; (6) The compressor successfully operated at water cooled condensing temperatures Due to temperature

  18. Intelligent Diagnosis Method for Centrifugal Pump System Using Vibration Signal and Support Vector Machine

    OpenAIRE

    Hongtao Xue; Zhongxing Li; Huaqing Wang; Peng Chen

    2014-01-01

    This paper proposed an intelligent diagnosis method for a centrifugal pump system using statistic filter, support vector machine (SVM), possibility theory, and Dempster-Shafer theory (DST) on the basis of the vibration signals, to diagnose frequent faults in the centrifugal pump at an early stage, such as cavitation, impeller unbalance, and shaft misalignment. Firstly, statistic filter is used to extract the feature signals of pump faults from the measured vibration signals across an optimum ...

  19. Damages on pumps and systems the handbook for the operation of centrifugal pumps

    CERN Document Server

    Merkle, Thomas

    2014-01-01

    Damage on Pumps and Systems. The Handbook for the Operation of Centrifugal Pumps offers a combination of the theoretical basics and practical experience for the operation of circulation pumps in the engineering industry. Centrifugal pumps and systems are extremely vulnerable to damage from a variety of causes, but the resulting breakdown can be prevented by ensuring that these pumps and systems are operated properly. This book provides a total overview of operating centrifugal pumps, including condition monitoring, preventive maintenance, life cycle costs, energy savings and economic aspects. Extra emphasis is given to the potential damage to these pumps and systems, and what can be done to prevent breakdown. Addresses specific issues about pumping of metal chips, sand, abrasive dust and other solids in fluidsEmphasis on economic and efficiency aspects of predictive maintenance and condition monitoring Uses life cycle costs (LCC) to evaluate and calculate the costs of pumping systems

  20. A Turbidity Test Based Centrifugal Microfluidics Diagnostic System for Simultaneous Detection of HBV, HCV, and CMV

    Directory of Open Access Journals (Sweden)

    Hung-Cheng Chang

    2015-01-01

    Full Text Available This paper presents a LAMP- (loop-mediated isothermal amplification- based lab-on-disk optical system that allows the simultaneous detection of hepatitis B virus, hepatitis C virus, and cytomegalovirus. The various flow stages are controlled in the proposed system using different balance among centrifugal pumping, Coriolis pumping, and the capillary force. We have implemented a servo system for positioning and speed control for the heating and centrifugal pumping. We have also successfully employed a polymer light-emitting diode section for turbidity detection. The easy-to-use one-click system can perform diagnostics in less than 1 hour.

  1. Centrifugal reciprocating compressor

    Science.gov (United States)

    High, W. H.

    1980-01-01

    Efficient compressor uses centrifugal force to compress gas. System incorporates two coupled dc motors, each driving separate centrifugal reciprocating-compressor assembly. Motors are synchronized to accelerate and decelerate alternately.

  2. A Stability Enhancement Method for Centrifugal Compressors using Active Control Casing Treatment System

    Science.gov (United States)

    Zhao, Yuanyang; Xiao, Jun; Li, Liansheng; Yang, Qichao; Liu, Guangbin; Wang, Le

    2015-08-01

    The centrifugal compressors are widely used in many fields. When the centrifugal compressors operate at the edge of the surge line, the compressor will be unstable. In addition, if the centrifugal compressor runs at this situation long time, the damage will be occurred on compressor. There are some kinds of method to improve and enlarge the range of the centrifugal compressors, such as inlet guide vane, and casing treatment. For casing treatment method, some structures have been researched, such as holed recirculation, basic slot casing treatment and groove casing treatment. All these researches are the passive methods. This paper present a new stability enhancement method based Active Control Casing Treatment (ACCT). All parts of this new method are introduced in detail. The control strategy of the system is mentioned in the paper. As a research sample, a centrifugal compressor having this system is researched using CFD method. The study focuses on the effect of the active control system on the impeller flow. The vortex in impeller is changed by the active control system. And this leads to the suppression of the extension of vortex blockage in impeller and to contribute to the enhancement of the compressor operating range.

  3. MODEL OF CENTRIFUGAL EFFECT AND ATTITUDE MANEUVER STABILITY OF A COUPLED RIGID-FLEXIBLE SYSTEM

    Institute of Scientific and Technical Information of China (English)

    LI Zhi-bin; WANG Zhao-lin; WANG Tian-shu; LIU Ning

    2005-01-01

    The influences of nonlinear centrifugal force to large overall attitude motion of coupled rigid-flexible system was investigated. First the nonlinear model of the coupled rigidflexible system was deduced from the idea of "cenlrifugal potential field", and then the dynamic effects of the nonlinear centrifugal force to system attitude motion were analyzed by approximate calculation; At last, the Lyapunov function based on energy norm was selected,in the condition that only the measured values of attitude and attitude speed are available,and it is proved that the PD feedback control law can ensure the attitude stability during large angle maneuver.

  4. Systems approach used in the Gas Centrifuge Enrichment Plant

    International Nuclear Information System (INIS)

    A requirement exists for effective and efficient transfer of technical knowledge from the design engineering team to the production work force. Performance-Based Training (PBT) is a systematic approach to the design, development, and implementation of technical training. This approach has been successfully used by the US Armed Forces, industry, and other organizations. The advantages of the PBT approach are: cost-effectiveness (lowest life-cycle training cost), learning effectiveness, reduced implementation time, and ease of administration. The PBT process comprises five distinctive and rigorous phases: Analysis of Job Performance, Design of Instructional Strategy, Development of Training Materials and Instructional Media, Validation of Materials and Media, and Implementation of the Instructional Program. Examples from the Gas Centrifuge Enrichment Plant (GCEP) are used to illustrate the application of PBT

  5. Numerical investigation of nonlinear vibration for rotor-seal system of centrifugal pump

    International Nuclear Information System (INIS)

    The exciting force in the seal is an important factor for the stability of a multiple stage centrifugal pump. With the speed increasing, the rotor system of multiple stage centrifugal pump presents some nonlinear characters. In order to provide supports for the research of nonlinear characters of multiple stage centrifugal pump, a rotor-seal system model of centrifugal pump is presented and the Muszynska nonlinear seal model is used to express the seal exciting force with multiple parameters in the paper. The fourth-order Runge-Kutta method is also used to determine the vibration response at the impeller place and obtain bifurcation diagram, axis orbit, phase diagram as well as Poincaré Map. The bifurcation results show that the rotor-seal system would be stable under a lower speed and change to be unstable as the rotor speed increases. Various multi-periodic motions and quasi-periodic motions are found showing the complicated motions in the rotor-seal system under nonlinear seal forces

  6. Novel localized heating technique on centrifugal microfluidic disc with wireless temperature monitoring system.

    Science.gov (United States)

    Joseph, Karunan; Ibrahim, Fatimah; Cho, Jongman

    2015-01-01

    Recent advances in the field of centrifugal microfluidic disc suggest the need for electrical interface in the disc to perform active biomedical assays. In this paper, we have demonstrated an active application powered by the energy harvested from the rotation of the centrifugal microfluidic disc. A novel integration of power harvester disc onto centrifugal microfluidic disc to perform localized heating technique is the main idea of our paper. The power harvester disc utilizing electromagnetic induction mechanism generates electrical energy from the rotation of the disc. This contributes to the heat generation by the embedded heater on the localized heating disc. The main characteristic observed in our experiment is the heating pattern in relative to the rotation of the disc. The heating pattern is monitored wirelessly with a digital temperature sensing system also embedded on the disc. Maximum temperature achieved is 82 °C at rotational speed of 2000 RPM. The technique proves to be effective for continuous heating without the need to stop the centrifugal motion of the disc.

  7. A Study of Using Artificial Neural Network in a Non-linear Centrifugal Compressor System

    Directory of Open Access Journals (Sweden)

    Prof. Pin-Chang Chen

    2012-12-01

    Full Text Available This study adopts the centrifugal compressor system which produces the nitric acid equipment in China Petrochemical Development Corporation’s Plant. The system is non-linear and its manufacturing process is changeable, which the traditional PID (Proportional-Integral-Differential control method is difficult to apply. This study is intended to apply the artificial neural network methodto test and forecast the compressor performance. By means of collecting the PLC (Programmable Logic Controller on-line data, the proposed method is applied to simulate the control system. According to the result of this study, the proposed method can reach the high accuracy, and make concrete contributions in promoting the safety of the centrifugal compressor system.

  8. Centrifuge modeling of monopiles

    DEFF Research Database (Denmark)

    Klinkvort, Rasmus Tofte

    2010-01-01

    To gain a larger knowledge of the monopile foundation concept, centrifuge modeling is used by the geotechnical group at DTU. The centrifuge operated at DTU is a beam centrifuge and was built in 1976. In the recent years it has been upgraded with onboard data acquisition and control systems....... The capabilities of the centrifuge at DTU makes it possible to obtain a scale factor of 85 in experiments which equals a soil volume in prototype scale of a diameter of 40 meters and a depth of 40 meters. This paper describes centrifuge modeling theory, the centrifuge setup at DTU and as an example show results...... from centrifuge tests performed on large diameter piles installed in dry sand....

  9. CMAS: fully integrated portable centrifugal microfluidic analysis system for on-site colorimetric analysis

    OpenAIRE

    Czugala, Monika; Maher, Damien; Collins, Fiachra; Burger, Robert; Hopfgartner, Frank; Yang, Yang; Zhou, Jiang; Ducree, Jens; Alan F. SMEATON; Fraser, Kevin J.; Benito-Lopez, Fernando; Diamond, Dermot

    2013-01-01

    A portable, wireless system capable of in-situ reagent-based colorimetric analysis is demonstrated. The system is based on a reconfigurable low cost optical detection method employing a paired emitter detector diode device, which allows a wide range of centrifugal microfluidic layouts to be implemented. Due to the wireless communication, acquisition parameters can be controlled remotely and results can be downloaded in distant locations and displayed in real time. The stand-alone capabilities...

  10. A Study of Using Artificial Neural Network in a Non-linear Centrifugal Compressor System

    OpenAIRE

    Prof. Pin-Chang Chen; Prof. Hung-Teng Chang; Mr. Armada Hsu

    2012-01-01

    This study adopts the centrifugal compressor system which produces the nitric acid equipment in China Petrochemical Development Corporation’s Plant. The system is non-linear and its manufacturing process is changeable, which the traditional PID (Proportional-Integral-Differential) control method is difficult to apply. This study is intended to apply the artificial neural network methodto test and forecast the compressor performance. By means of collecting the PLC (Programmable Logic Controlle...

  11. Centrifugal Microfluidic System for Nucleic Acid Amplification and Detection.

    Science.gov (United States)

    Miao, Baogang; Peng, Niancai; Li, Lei; Li, Zheng; Hu, Fei; Zhang, Zengming; Wang, Chaohui

    2015-11-04

    We report here the development of a rapid PCR microfluidic system comprising a double-shaft turntable and centrifugal-based disc that rapidly drives the PCR mixture between chambers set at different temperatures, and the bidirectional flow improved the space utilization of the disc. Three heating resistors and thermistors maintained uniform, specific temperatures for the denaturation, annealing, and extension steps of the PCR. Infrared imaging showed that there was little thermal interference between reaction chambers; the system enabled the cycle number and reaction time of each step to be independently adjusted. To validate the function and efficiency of the centrifugal microfluidic system, a 350-base pair target gene from the hepatitis B virus was amplified and quantitated by fluorescence detection. By optimizing the cycling parameters, the reaction time was reduced to 32 min as compared to 120 min for a commercial PCR machine. DNA samples with concentrations ranging from 10 to 10⁶ copies/mL could be quantitatively analyzed using this system. This centrifugal-based microfluidic platform is a useful system and possesses industrialization potential that can be used for portable diagnostics.

  12. Test of an extruder feed system on the Tore Supra centrifugal pellet injector

    International Nuclear Information System (INIS)

    A deuterium ice extruder feed system has been developed by ORNL for adaptation to the existing ORNL Centrifugal Pellet Injector installed on Tore Supra. A detailed assessment of this feed system coupled to the centrifugal launcher has been carried out in a dedicated test bed at Cadarache, to complete and understand the first results obtained at ORNL and to improve them. The results presented in this paper are related to the study of the pellet trajectory from the deuterium ice cutting to the collection of the accelerated pellets in a guide tube. The overall reliability of the injector has been shown to be very sensitive to deviations in the free flight part of the trajectory, before capture by the rotating launcher

  13. Numerical analysis and centrifugal modeling of LNAPLs transport in subsurface system

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The transport of non-aqueous phase liquids (NAPLs) in unsaturated soils and groundwater is an important research topic in geo-environmental engineering. In this paper, the mechanism of light NAPLs (LNAPLs) transport in subsurface system is briefly introduced, and the mass transport equations, fluid flow equations, and the constitutive model of relative permeability - saturation - capillary pressure are discussed. Then the numerical method is introduced to simulate the multiphase flow problems in porous media, and the tempospatial distribution of LNAPLs is obtained. Moreover, different boundary conditions are employed in numerical simulation to investigate its effect on transport behavior. To verify the numerical data, centrifugal tests are conducted to model the LNAPLs migration in unsaturated soils and groundwater. The calculation results are agreeable with the experimental findings of centrifugal modeling, which indicates that LNAPLs from leaking point move downwards due to gravity force, and form a high concentration zone above the capillary fringe, and then spread out laterally along the groundwater table. Some LNAPL enters groundwater system to further migrate. The combination of numerical simulation and centrifuge modeling can be a useful means to study the transport behavior of LNAPLs in subsurface system.

  14. Online Parameter Estimation for a Centrifugal Decanter System

    DEFF Research Database (Denmark)

    Larsen, Jesper Abildgaard; Alstrøm, Preben

    2014-01-01

    In many processing plants decanter systems are used for separation of heterogenious mixtures, and even though they account for a large fraction of the energy consumption, most decanters just runs at a fixed setpoint. Here, multi model estimation is applied to a waste water treatment plant, and it...

  15. Study of a centrifugal blood pump in a mock loop system.

    Science.gov (United States)

    Uebelhart, Beatriz; da Silva, Bruno Utiyama; Fonseca, Jeison; Bock, Eduardo; Leme, Juliana; da Silva, Cibele; Leão, Tarcísio; Andrade, Aron

    2013-11-01

    An implantable centrifugal blood pump (ICBP) is being developed to be used as a ventricular assist device (VAD) in patients with severe cardiovascular diseases. The ICBP system is composed of a centrifugal pump, a motor, a controller, and a power supply. The electricity source provides power to the controller and to a motor that moves the pump's rotor through magnetic coupling. The centrifugal pump is composed of four parts: external conical house, external base, impeller, and impeller base. The rotor is supported by a pivot bearing system, and its impeller base is responsible for sheltering four permanent magnets. A hybrid cardiovascular simulator (HCS) was used to evaluate the ICBP's performance. A heart failure (HF) (when the heart increases beat frequency to compensate for decrease in blood flow) was simulated in the HCS. The main objective of this work is to analyze changes in physiological parameters such as cardiac output, blood pressure, and heart rate in three situations: healthy heart, HF, and HF with left circulatory assistance by ICBP. The results showed that parameters such as aortic pressure and cardiac output affected by the HF situation returned to normal values when the ICBP was connected to the HCS. In conclusion, the test results showed satisfactory performance for the ICBP as a VAD.

  16. A fluorescence-based centrifugal microfluidic system for parallel detection of multiple allergens

    Science.gov (United States)

    Chen, Q. L.; Ho, H. P.; Cheung, K. L.; Kong, S. K.; Suen, Y. K.; Kwan, Y. W.; Li, W. J.; Wong, C. K.

    2010-02-01

    This paper reports a robust polymer based centrifugal microfluidic analysis system that can provide parallel detection of multiple allergens in vitro. Many commercial food products (milk, bean, pollen, etc.) may introduce allergy to people. A low-cost device for rapid detection of allergens is highly desirable. With this as the objective, we have studied the feasibility of using a rotating disk device incorporating centrifugal microfluidics for performing actuationfree and multi-analyte detection of different allergen species with minimum sample usage and fast response time. Degranulation in basophils or mast cells is an indicator to demonstrate allergic reaction. In this connection, we used acridine orange (AO) to demonstrate degranulation in KU812 human basophils. It was found that the AO was released from granules when cells were stimulated by ionomycin, thus signifying the release of histamine which accounts for allergy symptoms [1-2]. Within this rotating optical platform, major microfluidic components including sample reservoirs, reaction chambers, microchannel and flow-control compartments are integrated into a single bio-compatible polydimethylsiloxane (PDMS) substrate. The flow sequence and reaction time can be controlled precisely. Sequentially through varying the spinning speed, the disk may perform a variety of steps on sample loading, reaction and detection. Our work demonstrates the feasibility of using centrifugation as a possible immunoassay system in the future.

  17. Surge Control of a Centrifugal Compression System by Using a Bouncing Ball

    Institute of Scientific and Technical Information of China (English)

    Yuichiro Asaga; Shimpei Mizuki; Hoshio Tsujita; Shinsuke Ohta

    2008-01-01

    The purpose of this study is to suppress the fluctuations of surge by a simple passive control method. A bouncing ball system with different weight of the balls was tested. As a result, the bouncing ball system suppressed mild surge without the deterioration of the performance characteristics, and moved the initiation point of surge toward the lower flow rate when the steel ball of 15mm outer diameter was used. The present system was effective to suppress the surge and to widen the stable operating range of a centrifugal compressor when the ball was chosen appropriately.

  18. Intelligent Diagnosis Method for Centrifugal Pump System Using Vibration Signal and Support Vector Machine

    Directory of Open Access Journals (Sweden)

    Hongtao Xue

    2014-01-01

    Full Text Available This paper proposed an intelligent diagnosis method for a centrifugal pump system using statistic filter, support vector machine (SVM, possibility theory, and Dempster-Shafer theory (DST on the basis of the vibration signals, to diagnose frequent faults in the centrifugal pump at an early stage, such as cavitation, impeller unbalance, and shaft misalignment. Firstly, statistic filter is used to extract the feature signals of pump faults from the measured vibration signals across an optimum frequency region, and nondimensional symptom parameters (NSPs are defined to represent the feature signals for distinguishing fault types. Secondly, the optimal classification hyperplane for distinguishing two states is obtained by SVM and NSPs, and its function is defined as synthetic symptom parameter (SSP in order to increase the diagnosis’ sensitivity. Finally, the possibility functions of the SSP are used to construct a sequential fuzzy diagnosis for fault detection and fault-type identification by possibility theory and DST. The proposed method has been applied to detect the faults of the centrifugal pump, and the efficiency of the method has been verified using practical examples.

  19. Automated and miniaturized detection of biological threats with a centrifugal microfluidic system

    Science.gov (United States)

    Mark, D.; van Oordt, T.; Strohmeier, O.; Roth, G.; Drexler, J.; Eberhard, M.; Niedrig, M.; Patel, P.; Zgaga-Griesz, A.; Bessler, W.; Weidmann, M.; Hufert, F.; Zengerle, R.; von Stetten, F.

    2012-06-01

    The world's growing mobility, mass tourism, and the threat of terrorism increase the risk of the fast spread of infectious microorganisms and toxins. Today's procedures for pathogen detection involve complex stationary devices, and are often too time consuming for a rapid and effective response. Therefore a robust and mobile diagnostic system is required. We present a microstructured LabDisk which performs complex biochemical analyses together with a mobile centrifugal microfluidic device which processes the LabDisk. This portable system will allow fully automated and rapid detection of biological threats at the point-of-need.

  20. Numerical and experimental investigation of a centrifugal compressor with an inducer casing bleed system

    Energy Technology Data Exchange (ETDEWEB)

    Hunziker, R.; Dickmann, H.P. [ABB Turbo Systems, Baden (Switzerland); Emmrich, R. [RWTH Aachen (Germany)

    2001-12-02

    State-of-the-art centrifugal compressors for turbocharger applications are required to provide broad compressor maps, high pressure ratios and high efficiency levels. Usually these requirements are perceived as contradictory and represent challenging design targets. Various techniques for map width enhancements have been reported since the early 1980s. ABB Turbo Systems Limited has adopted a simple bleed system for internal flow recirculation to a high flowrate, high efficiency, pressure ratio 4.2 centrifugal compressor stage. After initial test runs had proved the effectiveness of the bleed system, computational fluid dynamics (CFD) calculations were performed in order to gain insight into the flow pattern in both the compressor stage and the bleed system. The simulations explain the effectiveness by comparing them with simulations without the bleed channel. Selected streamline and iso-surface plots show the effect of the bleed channel flow on the main flow through the impeller. Four more variants of bleed channels have been modelled and investigated by CFD In order to optimize the bleed slot location and dimension. The most promising configuration, which showed a significant improvement in map width without a loss in efficiency, was subsequently built and tested. This test confirmed the validity of the CFD simulation results. (author)

  1. A new method of providing pulsatile flow in a centrifugal pump: assessment of pulsatility using a mock circulatory system.

    Science.gov (United States)

    Herreros, Jesús; Berjano, Enrique J; Sales-Nebot, Laura; Más, Pedro; Calvo, Irene; Mastrobuoni, Stefano; Mercé, Salvador

    2008-06-01

    Previous studies have demonstrated the potential advantages of pulsatile flow as compared with continuous flow. However, to date, physiologic pumps have been technically complex and their application has therefore remained in the experimental field. We have developed a new type of centrifugal pump, which can provide pulsatile as well as continuous flow. The inner wall of a centrifugal pump is pulsed by means of a flexible membrane, which can be accurately controlled by means of either a hydraulic or pneumatic driver. The aim of this study was to assess the hydraulic behavior of the new pump in terms of surplus hemodynamic energy (SHE). We conducted experiments using a mock circulatory system including a membrane oxygenator. No differences were found in the pressure-flow characteristics between the new pump and a conventional centrifugal pump, suggesting that the inclusion of the flexible membrane does not alter hydraulic performance. The value of SHE rose when systolic volume was increased. However, SHE dropped when the percentage of ejection time was reduced and also when the continuous flow (programmed by the centrifugal console) increased. Mean flow matched well with the continuous flow set by the centrifugal console, that is, the pulsatile component of the flow was exclusively controlled by the pulsatile console, and was therefore independent of the continuous flow programmed by the centrifugal console. The pulsatility of the new pump was approximately 25% of that created with a truly pulsatile pump.

  2. Design and optimization of a single stage centrifugal compressor for a solar dish-Brayton system

    Science.gov (United States)

    Wang, Yongsheng; Wang, Kai; Tong, Zhiting; Lin, Feng; Nie, Chaoqun; Engeda, Abraham

    2013-10-01

    According to the requirements of a solar dish-Brayton system, a centrifugal compressor stage with a minimum total pressure ratio of 5, an adiabatic efficiency above 75% and a surge margin more than 12% needs to be designed. A single stage, which consists of impeller, radial vaned diffuser, 90° crossover and two rows of axial stators, was chosen to satisfy this system. To achieve the stage performance, an impeller with a 6:1 total pressure ratio and an adiabatic efficiency of 90% was designed and its preliminary geometry came from an in-house one-dimensional program. Radial vaned diffuser was applied downstream of the impeller. Two rows of axial stators after 90° crossover were added to guide the flow into axial direction. Since jet-wake flow, shockwave and boundary layer separation coexisted in the impeller-diffuser region, optimization on the radius ratio of radial diffuser vane inlet to impeller exit, diffuser vane inlet blade angle and number of diffuser vanes was carried out at design point. Finally, an optimized centrifugal compressor stage fulfilled the high expectations and presented proper performance. Numerical simulation showed that at design point the stage adiabatic efficiency was 79.93% and the total pressure ratio was 5.6. The surge margin was 15%. The performance map including 80%, 90% and 100% design speed was also presented.

  3. Experimental Study on Active Control of Surge in a Centrifugal Compression System

    Directory of Open Access Journals (Sweden)

    Nie Chaoqun

    2000-01-01

    Full Text Available An experimental study has been carried out on the active control of surge in a centrifugal compression system. With a computerized on-line control scheme, the surge phenomenon is suppressed and the stable operating range of the system is extended. In order to design the active control scheme and choose the desired parameters of the control system inputs, special emphases have been placed on the development of surge inception and the nonlinear interaction between the system and the actuator. By use of the method designed in the present work, the results of active control onsurge have been demonstrated for the different B parameters, different prescribed criteria and different control frequencies.

  4. Centrifugal pumps

    CERN Document Server

    Anderson, HH

    1981-01-01

    Centrifugal Pumps describes the whole range of the centrifugal pump (mixed flow and axial flow pumps are dealt with more briefly), with emphasis on the development of the boiler feed pump. Organized into 46 chapters, this book discusses the general hydrodynamic principles, performance, dimensions, type number, flow, and efficiency of centrifugal pumps. This text also explains the pumps performance; entry conditions and cavitation; speed and dimensions for a given duty; and losses. Some chapters further describe centrifugal pump mechanical design, installation, monitoring, and maintenance. The

  5. CENTRIFUGAL SEPARATORS

    Science.gov (United States)

    Skarstrom, C.

    1959-03-10

    A centrifugal separator is described for separating gaseous mixtures where the temperature gradients both longitudinally and radially of the centrifuge may be controlled effectively to produce a maximum separation of the process gases flowing through. Tbe invention provides for the balancing of increases and decreases in temperature in various zones of the centrifuge chamber as the result of compression and expansions respectively, of process gases and may be employed effectively both to neutralize harmful temperature gradients and to utilize beneficial temperaturc gradients within the centrifuge.

  6. The evolution of the centrifugal visual system of vertebrates. A cladistic analysis and new hypotheses.

    Science.gov (United States)

    Repérant, J; Médina, M; Ward, R; Miceli, D; Kenigfest, N B; Rio, J P; Vesselkin, N P

    2007-01-01

    In a recent review of the available data concerning the centrifugal visual system (CVS) of vertebrates [Repérant, J., Ward, R., Miceli, D., Rio, J.P., Médina, M., Kenigfest, N.B., Vesselkin, N.P., 2006. The centrifugal visual system of vertebrates: a comparative analysis of its functional anatomical organization, Brain Res. Rev. 52, 1-57], we have shown that this feature of the visual system is not a particularity of birds, but is a permanent component of the vertebrate central nervous system which nevertheless shows considerable morphological and functional variation from one taxonomic group to another. Given these findings, the primary objective of the present article is an attempt to specify the evolutionary significance of this phylogenetic diversity. We begin by drawing up an inventory of this variation under several headings: the intracerebral location of the retinopetal neurons; the mode of intra-retinal arborizations of the centrifugal fibres and the nature of their targets; their neurochemical properties; and the afferent supplies of these neurons. We subsequently discuss these variations, particularly that of the intracerebral location of the retinopetal neurons during development and in adult forms, using the neuromeric terminology and in the framework of cladistic analysis, and seek to interpret them in a phylogenetic context. From this analysis, it becomes evident that the CVS is not a homogeneous entity formed by neurons with a common embryological origin, but rather a collection of at least eight distinct subsystems arising in very different regions of the neuraxis. These are the olfacto-retinal, dorsal thalamo-retinal, ventral thalamo-retinal, pretecto-retinal, tecto-retinal, tegmento-mesencephalo-retinal, dorsal isthmo-retinal and ventral isthmo-retinal systems. The olfacto-retinal system, which is probably absent in Agnatha, appears to be a pleisiomorphic characteristic of all Gnathostomata, while on the other hand the tegmento

  7. System-level network simulation for robust centrifugal-microfluidic lab-on-a-chip systems.

    Science.gov (United States)

    Schwarz, I; Zehnle, S; Hutzenlaub, T; Zengerle, R; Paust, N

    2016-05-10

    Centrifugal microfluidics shows a clear trend towards a higher degree of integration and parallelization. This trend leads to an increase in the number and density of integrated microfluidic unit operations. The fact that all unit operations are processed by the same common spin protocol turns higher integration into higher complexity. To allow for efficient development anyhow, we introduce advanced lumped models for network simulations in centrifugal microfluidics. These models consider the interplay of centrifugal and Euler pressures, viscous dissipation, capillary pressures and pneumatic pressures. The simulations are fast and simple to set up and allow for the precise prediction of flow rates as well as switching and valving events. During development, channel and chamber geometry variations due to manufacturing tolerances can be taken into account as well as pipetting errors, variations of contact angles, compliant chamber walls and temperature variations in the processing device. As an example of considering these parameters during development, we demonstrate simulation based robustness analysis for pneumatic siphon valving in centrifugal microfluidics. Subsequently, the influence of liquid properties on pumping and valving is studied for four liquids relevant for biochemical analysis, namely, water (large surface tension), blood plasma (large contact angle hysteresis), ethanol/water (highly wetting) and glycerine/water (highly viscous). In a second example, we derive a spin protocol to attain a constant flow rate under varying pressure conditions. Both examples show excellent agreement with experimental validations. PMID:27095248

  8. System-level network simulation for robust centrifugal-microfluidic lab-on-a-chip systems.

    Science.gov (United States)

    Schwarz, I; Zehnle, S; Hutzenlaub, T; Zengerle, R; Paust, N

    2016-05-10

    Centrifugal microfluidics shows a clear trend towards a higher degree of integration and parallelization. This trend leads to an increase in the number and density of integrated microfluidic unit operations. The fact that all unit operations are processed by the same common spin protocol turns higher integration into higher complexity. To allow for efficient development anyhow, we introduce advanced lumped models for network simulations in centrifugal microfluidics. These models consider the interplay of centrifugal and Euler pressures, viscous dissipation, capillary pressures and pneumatic pressures. The simulations are fast and simple to set up and allow for the precise prediction of flow rates as well as switching and valving events. During development, channel and chamber geometry variations due to manufacturing tolerances can be taken into account as well as pipetting errors, variations of contact angles, compliant chamber walls and temperature variations in the processing device. As an example of considering these parameters during development, we demonstrate simulation based robustness analysis for pneumatic siphon valving in centrifugal microfluidics. Subsequently, the influence of liquid properties on pumping and valving is studied for four liquids relevant for biochemical analysis, namely, water (large surface tension), blood plasma (large contact angle hysteresis), ethanol/water (highly wetting) and glycerine/water (highly viscous). In a second example, we derive a spin protocol to attain a constant flow rate under varying pressure conditions. Both examples show excellent agreement with experimental validations.

  9. Experiment and surge analysis of centrifugal two-stage turbocharging system

    Institute of Scientific and Technical Information of China (English)

    Yituan HE; Chaochen MA

    2008-01-01

    To study a centrifugal two-stage turbocharging system's surge and influencing factors, a special test bench was set up and the system surge test was performed. The test results indicate that the measured parameters such as air mass flow and rotation speed of a high pressure (HP) stage compressor can be converted into corrected para-meters under a standard condition according to the Mach number similarity criterion, because the air flow in a HP stage compressor has entered the Reynolds number (Re) auto-modeling range. Accordingly, the reasons leading to a two-stage turbocharging system's surge can be analyzed according to the corrected mass flow characteristic maps and actual operating conditions of HP and low pressure (LP) stage compressors.

  10. Microfluidic devices, systems, and methods for quantifying particles using centrifugal force

    Science.gov (United States)

    Schaff, Ulrich Y.; Sommer, Gregory J.; Singh, Anup K.

    2015-11-17

    Embodiments of the present invention are directed toward microfluidic systems, apparatus, and methods for measuring a quantity of cells in a fluid. Examples include a differential white blood cell measurement using a centrifugal microfluidic system. A method may include introducing a fluid sample containing a quantity of cells into a microfluidic channel defined in part by a substrate. The quantity of cells may be transported toward a detection region defined in part by the substrate, wherein the detection region contains a density media, and wherein the density media has a density lower than a density of the cells and higher than a density of the fluid sample. The substrate may be spun such that at least a portion of the quantity of cells are transported through the density media. Signals may be detected from label moieties affixed to the cells.

  11. Pressure pulsations in piping system excited by a centrifugal turbomachinery taking the damping characteristics into consideration

    Science.gov (United States)

    Hayashi, I.; Kaneko, S.

    2014-02-01

    Pressure pulsations excited by a centrifugal turbomachinery such as compressor, fan or pump at the blade passing frequency may cause severe noise and vibrations in piping system. Therefore, the practical evaluation method of pressure pulsations is strongly recommended. In particular, the maximum pressure amplitude under the resonant conditions should be appropriately evaluated. In this study, a one-dimensional excitation source model for a compressor or pump is introduced based on the equation of motion, so as to incorporate the non-linear damping proportional to velocity squared in the total piping system including the compressor or pump. The damping characteristics of the compressor or pump are investigated by using the semi-empirical model. It is shown that the resistance coefficient of the compressor or pump depends on the Reynolds number that is defined using the equivalent velocity of the pulsating flow. The frequency response of the pressure amplitude and the pressure distribution in the piping system can be evaluated by introducing the equivalent resistance of the compressor or pump and that of piping system. In particular, the relation of the maximum pressure amplitude in piping system to the location of the excitation source under resonant conditions can be evaluated. Finally, the reduction of the pressure pulsations by use of an orifice plate is discussed in terms of the pulsation energy loss.

  12. Centrifugal accelerator, system and method for removing unwanted layers from a surface

    Science.gov (United States)

    Foster, Christopher A.; Fisher, Paul W.

    1995-01-01

    A cryoblasting process having a centrifugal accelerator for accelerating frozen pellets of argon or carbon dioxide toward a target area utilizes an accelerator throw wheel designed to induce, during operation, the creation of a low-friction gas bearing within internal passages of the wheel which would otherwise retard acceleration of the pellets as they move through the passages. An associated system and method for removing paint from a surface with cryoblasting techniques involves the treating, such as a preheating, of the painted surface to soften the paint prior to the impacting of frozen pellets thereagainst to increase the rate of paint removal. A system and method for producing large quantities of frozen pellets from a liquid material, such as liquid argon or carbon dioxide, for use in a cryoblasting process utilizes a chamber into which the liquid material is introduced in the form of a jet which disintegrates into droplets. A non-condensible gas, such as inert helium or air, is injected into the chamber at a controlled rate so that the droplets freeze into bodies of relatively high density.

  13. Root cause analysis of vibrations and pulsations in a naphtha pipe system with centrifugal pumps

    NARCIS (Netherlands)

    Bokhorst, E. van; Almasy, S.

    2010-01-01

    The capacity of a platform installation consisting of naphtha feed lines from centrifugal pumps to an oven has been increased by 25 % in combination with rerouting of the piping layout upstream of the oven and inside the convection zone. The operating company observed considerable increase of the vi

  14. Centrifugal microfluidics for biomedical applications.

    Science.gov (United States)

    Gorkin, Robert; Park, Jiwoon; Siegrist, Jonathan; Amasia, Mary; Lee, Beom Seok; Park, Jong-Myeon; Kim, Jintae; Kim, Hanshin; Madou, Marc; Cho, Yoon-Kyoung

    2010-07-21

    The centrifugal microfluidic platform has been a focus of academic and industrial research efforts for almost 40 years. Primarily targeting biomedical applications, a range of assays have been adapted on the system; however, the platform has found limited commercial success as a research or clinical tool. Nonetheless, new developments in centrifugal microfluidic technologies have the potential to establish wide-spread utilization of the platform. This paper presents an in-depth review of the centrifugal microfluidic platform, while highlighting recent progress in the field and outlining the potential for future applications. An overview of centrifugal microfluidic technologies is presented, including descriptions of advantages of the platform as a microfluidic handling system and the principles behind centrifugal fluidic manipulation. The paper also discusses a history of significant centrifugal microfluidic platform developments with an explanation of the evolution of the platform as it pertains to academia and industry. Lastly, we review the few centrifugal microfluidic-based sample-to-answer analysis systems shown to date and examine the challenges to be tackled before the centrifugal platform can be more broadly accepted as a new diagnostic platform. In particular, fully integrated, easy to operate, inexpensive and accurate microfluidic tools in the area of in vitro nucleic acid diagnostics are discussed.

  15. Centrifugal analyzer development

    International Nuclear Information System (INIS)

    The development of the centrifuge fast analyzer (CFA) is reviewed. The development of a miniature CFA with computer data analysis is reported and applications for automated diagnostic chemical and hematological assays are discussed. A portable CFA system with microprocessor was adapted for field assays of air and water samples for environmental pollutants, including ammonia, nitrates, nitrites, phosphates, sulfates, and silica. 83 references

  16. Hydraulic Calculation Method for the Fluid Delivery System of Centrifugal Pump%离心泵流体输送系统水力计算方法

    Institute of Scientific and Technical Information of China (English)

    徐宏斌

    2001-01-01

    简述离心泵和管路的特性,介绍离心泵流体输送管路系统的水力计算方法,以及如何确定泵的安装高度。%The characteristics of centrifugal pump and pipeline are brieflyelaborated. The hydraulic calculation method for fluid delivery pipeline system of centrifugal pump and the method of determining the pump installation height are introduced.

  17. Design of an Unattended Environmental Aerosol Sampling and Analysis System for Gaseous Centrifuge Enrichment Plants

    International Nuclear Information System (INIS)

    The resources of the IAEA continue to be challenged by the rapid, worldwide expansion of nuclear energy production. Gaseous centrifuge enrichment plants (GCEPs) represent an especially formidable dilemma to the application of safeguard measures, as the size and enrichment capacity of GCEPs continue to escalate. During the early part of the 1990's, the IAEA began to lay the foundation to strengthen and make cost-effective its future safeguard regime. Measures under Part II of 'Programme 93+2' specifically sanctioned access to nuclear fuel production facilities and environmental sampling by IAEA inspectors. Today, the Additional Protocol grants inspection and environmental sample collection authority to IAEA inspectors at GCEPs during announced and low frequency unannounced (LFUA) inspections. During inspections, IAEA inspectors collect environmental swipe samples that are then shipped offsite to an analytical laboratory for enrichment assay. This approach has proven to be an effective deterrence to GCEP misuse, but this method has never achieved the timeliness of detection goals set forth by IAEA. Furthermore it is questionable whether the IAEA will have the resources to even maintain pace with the expansive production capacity of the modern GCEP, let alone improve the timeliness in reaching current safeguards conclusions. New safeguards propositions, outside of familiar mainstream safeguard measures, may therefore be required that counteract the changing landscape of nuclear energy fuel production. A new concept is proposed that offers rapid, cost effective GCEP misuse detection, without increasing LFUA inspection access or introducing intrusive access demands on GCEP operations. Our approach is based on continuous onsite aerosol collection and laser enrichment analysis. This approach mitigates many of the constraints imposed by the LFUA protocol, reduces the demand for onsite sample collection and offsite analysis, and overcomes current limitations associated with

  18. Centrifugal pyrocontactor

    Science.gov (United States)

    Chow, Lorac S.; Leonard, Ralph A.

    1993-01-01

    A method for mixing and separating immiscible liquid salts and liquid metals in a centrifugal contractor. The method includes introducing the liquids into an annular mixing zone and intensely mixing the liquids using vertical vanes attached to a rotor cooperating with vertical baffles, a horizontal baffle, and bottom vanes attached to the contactor housing. The liquids enter the contactor in the range of 700-800 degrees Celsius. The liquids are separated in the rotor into a dense phase and a light phase which are discharged from the contactor.

  19. Control of Surge in Centrifugal Compressor by Using a Nozzle Injection System: Universality in Optimal Position of Injection Nozzle

    OpenAIRE

    Toshiyuki Hirano; Takanori Uchida; Hoshio Tsujita

    2012-01-01

    The passive control method for surge and rotating stall in centrifugal compressors by using a nozzle injection system was proposed to extend the stable operating range to the low flow rate. A part of the flow at the scroll outlet of a compressor was recirculated to an injection nozzle installed on the inner wall of the suction pipe of the compressor through the bypass pipe and injected to the impeller inlet. Two types of compressors were tested at the rotational speeds of 50,000 rpm and 60,0...

  20. Performance enhanced design of chaos controller for the mechanical centrifugal flywheel governor system via adaptive dynamic surface control

    Science.gov (United States)

    Luo, Shaohua; Hou, Zhiwei; Zhang, Tao

    2016-09-01

    This paper addresses chaos suppression of the mechanical centrifugal flywheel governor system with output constraint and fully unknown parameters via adaptive dynamic surface control. To have a certain understanding of chaotic nature of the mechanical centrifugal flywheel governor system and subsequently design its controller, the useful tools like the phase diagrams and corresponding time histories are employed. By using tangent barrier Lyapunov function, a dynamic surface control scheme with neural network and tracking differentiator is developed to transform chaos oscillation into regular motion and the output constraint rule is not broken in whole process. Plugging second-order tracking differentiator into chaos controller tackles the "explosion of complexity" of backstepping and improves the accuracy in contrast with the first-order filter. Meanwhile, Chebyshev neural network with adaptive law whose input only depends on a subset of Chebyshev polynomials is derived to learn the behavior of unknown dynamics. The boundedness of all signals of the closed-loop system is verified in stability analysis. Finally, the results of numerical simulations illustrate effectiveness and exhibit the superior performance of the proposed scheme by comparing with the existing ADSC method.

  1. Performance enhanced design of chaos controller for the mechanical centrifugal flywheel governor system via adaptive dynamic surface control

    Directory of Open Access Journals (Sweden)

    Shaohua Luo

    2016-09-01

    Full Text Available This paper addresses chaos suppression of the mechanical centrifugal flywheel governor system with output constraint and fully unknown parameters via adaptive dynamic surface control. To have a certain understanding of chaotic nature of the mechanical centrifugal flywheel governor system and subsequently design its controller, the useful tools like the phase diagrams and corresponding time histories are employed. By using tangent barrier Lyapunov function, a dynamic surface control scheme with neural network and tracking differentiator is developed to transform chaos oscillation into regular motion and the output constraint rule is not broken in whole process. Plugging second-order tracking differentiator into chaos controller tackles the “explosion of complexity” of backstepping and improves the accuracy in contrast with the first-order filter. Meanwhile, Chebyshev neural network with adaptive law whose input only depends on a subset of Chebyshev polynomials is derived to learn the behavior of unknown dynamics. The boundedness of all signals of the closed-loop system is verified in stability analysis. Finally, the results of numerical simulations illustrate effectiveness and exhibit the superior performance of the proposed scheme by comparing with the existing ADSC method.

  2. A comprehensive classification of solvent systems used for natural product purifications in countercurrent and centrifugal partition chromatography.

    Science.gov (United States)

    Skalicka-Woźniak, Krystyna; Garrard, Ian

    2015-11-01

    Using both library paper copies and modern electronic copies, every known, published, English-language journal paper that employs either countercurrent or centrifugal partition chromatography solvent systems for natural product purifications has been studied and the solvent systems classified in a comprehensive database. Papers were studied from the earliest found examples containing natural product separations in 1984 until the end of 2014. In total, 2594 solvent systems have been classified, of which 272 are gradient systems. To observe any trends or patterns in the data, the natural product solutes were divided into 21 classes and the solvent systems into 7 different types. The complete database, sorted according to natural product class, is available for download to assist separation scientists in future liquid-liquid chromatography purifications. PMID:26219437

  3. Centrifugal pumps

    CERN Document Server

    Gülich, Johann Friedrich

    2014-01-01

    This book gives an unparalleled, up-to-date, in-depth treatment of all kinds of flow phenomena encountered in centrifugal pumps including the complex interactions of fluid flow with vibrations and wear of materials. The scope includes all aspects of hydraulic design, 3D-flow phenomena and partload operation, cavitation, numerical flow calculations, hydraulic forces, pressure pulsations, noise, pump vibrations (notably bearing housing vibration diagnostics and remedies), pipe vibrations, pump characteristics and pump operation, design of intake structures, the effects of highly viscous flows, pumping of gas-liquid mixtures, hydraulic transport of solids, fatigue damage to impellers or diffusers, material selection under the aspects of fatigue, corrosion, erosion-corrosion or hydro-abrasive wear, pump selection, and hydraulic quality criteria. As a novelty, the 3rd ed. brings a fully analytical design method for radial impellers, which eliminates the arbitrary choices inherent to former design procedures. The d...

  4. Centrifugal contactor modified for end stage operation in a multistage system

    Science.gov (United States)

    Jubin, Robert T.

    1990-01-01

    A cascade formed of a plurality of centrifugal contactors useful for countercurrent solvent extraction processes such as utilizable for the reprocessing of nuclear reactor fuels is modified to permit operation in the event one or both end stages of the cascade become inoperative. Weir assemblies are connected to each of the two end stages by suitable conduits for separating liquids discharged from an inoperative end stage based upon the weight of the liquid phases uses in the solvent extraction process. The weir assembly at one end stage is constructed to separate and discharge the heaviest liquid phase while the weir assembly at the other end stage is constructed to separate and discharge the lightest liquid phase. These weir assemblies function to keep the liquid discharge from an inoperative end stages on the same weight phase a would occur from an operating end stage.

  5. Control of Surge in Centrifugal Compressor by Using a Nozzle Injection System: Universality in Optimal Position of Injection Nozzle

    Directory of Open Access Journals (Sweden)

    Toshiyuki Hirano

    2012-01-01

    Full Text Available The passive control method for surge and rotating stall in centrifugal compressors by using a nozzle injection system was proposed to extend the stable operating range to the low flow rate. A part of the flow at the scroll outlet of a compressor was recirculated to an injection nozzle installed on the inner wall of the suction pipe of the compressor through the bypass pipe and injected to the impeller inlet. Two types of compressors were tested at the rotational speeds of 50,000 rpm and 60,000 rpm with the parameter of the circumferential position of the injection nozzle. The present experimental results revealed that the optimum circumferential position, which most effectively reduced the flow rate for the surge inception, existed at the opposite side of the tongue of the scroll against the rotational axis and did not depend on the compressor system and the rotational speeds.

  6. Development of a fully integrated analysis system for ions based on ion-selective optodes and centrifugal microfluidics

    Science.gov (United States)

    Johnson, R. D.; Badr, I. H.; Barrett, G.; Lai, S.; Lu, Y.; Madou, M. J.; Bachas, L. G.; Daunert, S. (Principal Investigator)

    2001-01-01

    A fully integrated, miniaturized analysis system for ions based on a centrifugal microfluidics platform and ion-selective optode membranes is described. The microfluidic architecture is composed of channels, five solution reservoirs, a measuring chamber, and a waste reservoir manufactured onto a disk-shaped substrate of poly(methyl methacrylate). Ion-selective optode membranes, composed of plasticized poly(vinyl chloride) impregnated with an ionophore, a proton chromoionophore, and a lipophilic anionic additive, were cast, with a spin-on device, onto a support layer and then immobilized on the disk. Fluid propulsion is achieved by the centrifugal force that results from spinning the disk, while a system of valves is built onto the disk to control flow. These valves operate based on fluid properties and fluid/substrate interactions and are controlled by the angular frequency of rotation. With this system, we have been able to deliver calibrant solutions, washing buffers, or "test" solutions to the measuring chamber where the optode membrane is located. An analysis system based on a potassium-selective optode has been characterized. Results indicate that optodes immobilized on the platform demonstrate theoretical responses in an absorbance mode of measurement. Samples of unknown concentration can be quantified to within 3% error by fitting the response function for a given optode membrane using an acid (for measuring the signal for a fully protonated chromoionophore), a base (for fully deprotonated chromoionophore), and two standard solutions. Further, the ability to measure ion concentrations by employing one standard solution in conjunction with acid and base and with two standards alone were studied to delineate whether the current architecture could be simplified. Finally, the efficacy of incorporating washing steps into the calibration protocol was investigated.

  7. Centrifugally decoupling touchdown bearings

    Science.gov (United States)

    Post, Richard F

    2014-06-24

    Centrifugally decoupling mechanical bearing systems provide thin tensioned metallic ribbons contained in a support structure. This assembly rotates around a stationary shaft being centered at low speeds by the action of the metal ribbons. Tension springs are connected on one end to the ribbons and on the other end to the support structure. The ribbons pass through slots in the inner ring of the support structure. The spring preloading thus insures contact (or near-contact) between the ribbons and the shaft at rotation speeds below the transition speed. Above this speed, however, the centrifugal force on the ribbons produces a tensile force on them that exceeds the spring tensile force so that the ribbons curve outward, effectively decoupling them from mechanical contact with the shaft. They still remain, however, in position to act as a touchdown bearing in case of abnormally high transverse accelerations.

  8. The Structure of Centrifugal Separator and its Control System%离心选矿机结构及其控制方法

    Institute of Scientific and Technical Information of China (English)

    李华杰

    2012-01-01

    Centrifugal separator is a kind of gravity separation equipment developed in the 1960s for dressing of low-grade and fine grained mineral. With the progress of technology, the integrated ore dressing technology with centrifugal separator has been gradually improved. The application of advanced automatic control technology make the working process of centrifugal separator more reliable and convenient, which greatly enhanced ore dressing performance of centrifugal separator. This article introduces the structure, components, working principle and automatic control system of centrifugal separator.%离心选矿机是国内60年代研制出的一种重选设备,适用于低品位、细粒级的钨矿石选别.随着技术的进步,离心选矿机选矿的综合技术日趋完善,特别是先进的自动控制技术的应用,使得离心选矿机的工作过程稳定可靠、调节方便,大大提升了离心选矿机的选矿效果.本文介绍了离心选矿机的结构组成、工作原理和自动控制系统.

  9. Biochemical Technology Program progress report for the period January 1--June 30, 1976. [Centrifugal analyzers and advanced analytical systems for blood and body fluids

    Energy Technology Data Exchange (ETDEWEB)

    Mrochek, J.E.; Burtis, C.A.; Scott, C.D. (comps.)

    1976-09-01

    This document, which covers the period January 1-June 30, 1976, describes progress in the following areas: (1) advanced analytical techniques for the clinical laboratory, (2) fast clinical analyzers, (3) development of a miniaturized analytical clinical laboratory system, (4) centrifugal fast analyzers for animal toxicological studies, and (5) chemical profile of body fluids.

  10. Enrichment: centrifuge process

    International Nuclear Information System (INIS)

    This short course is divided into three sections devoted respectively to the physics of the process, some practical problems raised by the design of a centrifuge and the present situation of centrifugation in the World. 31 figs., 18 refs

  11. Centrifuge facilities at Technical University of Denmark

    DEFF Research Database (Denmark)

    Leth, Caspar Thrane; Krogsbøll, Anette Susanne; Hededal, Ole

    2008-01-01

    The geotechnical group at the Danish Technical University (DTU) operates a geotechnical beam centrifuge. The centrifuge was build in 1976 and has been upgraded through the years, latest with onboard data and control systems. The centrifuge concept involves an increased gravity field in which...... the physical model is placed and tested. The capabilities of the centrifuge at DTU makes it possible to obtain a scale factor of 75-85 in the tests which equals a soil volume in prototype scale of ø40m and a depth of 36 m. The centrifuge facilities at DTU have through the years been used for testing various...... geotechnical issues, such as suction anchors, tension piles in clay, active earth pressures on sheet piles and group effects for lateral loaded piles. The paper describes physical modelling in general, the centrifuge, present setups and shows samples of obtained results....

  12. Centrifugal separators and related devices and methods

    Science.gov (United States)

    Meikrantz, David H.; Law, Jack D.; Garn, Troy G.; Macaluso, Lawrence L.; Todd, Terry A.

    2012-03-06

    Centrifugal separators and related methods and devices are described. More particularly, centrifugal separators comprising a first fluid supply fitting configured to deliver fluid into a longitudinal fluid passage of a rotor shaft and a second fluid supply fitting sized and configured to sealingly couple with the first fluid supply fitting are described. Also, centrifugal separator systems comprising a manifold having a drain fitting and a cleaning fluid supply fitting are described, wherein the manifold is coupled to a movable member of a support assembly. Additionally, methods of cleaning centrifugal separators are described.

  13. Development and application of centrifugal model test system for break of earth-rock dams%Development and application of centrifugal model test system for break of earth-rock dams

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    A centrifugal model test system is successfully developed for the study of the break of earth-rock dams. A rotational water-supply ring is fixed to ensure adequate water amount for simulating scouring flow against the dam body in the test under accelerated velocity conditions. Advanced data measur- ing methods and image capturing devices are used to capture in multiple directions the images of overall dam break processes under accelerated velocity and mud flow conditions. A model dam with height 32cm is used to simulate the overtopping failure of 3 homogeneous earth-rock dams. The mechanism of the dam break is clearly revealied, and the effect of dam height on the dam break and the hydrograph of flood flow is investigated. The results show that the higher the dam is, the greater the longitudinal downward cuting and the side slope collapse of the break are, the steeper the curve of the hydrograph of flood flow at the break is, the faster the peak flow discharge develops and the earlier the peak flow reaches its maximum amount, the shorter the duration of dam break becomes. As a result, the more serious the damage caused by the break will be.

  14. Isolation by a sensitive centrifugation cell culture system of 52 strains of spotted fever group rickettsiae from ticks collected in France.

    OpenAIRE

    Péter, O; Raoult, D.; Gilot, B.

    1990-01-01

    Boutonneuse fever caused by Rickettsia conorii is transmitted mainly by the brown dog tick, Rhipicephalus sanguineus. We collected 540 ticks in Marseille, France, and tried to isolate as many strains of rickettsia as possible. Ticks were evaluated for the presence of rickettsia by the hemolymph test and by a new culture system, the centrifugation-shell vial technique. We avoided contamination in the culture system. Prior to ticks being submitted to the hemolymph test, they were disinfected. O...

  15. Implantable centrifugal blood pump with dual impeller and double pivot bearing system: electromechanical actuator, prototyping, and anatomical studies.

    Science.gov (United States)

    Bock, Eduardo; Antunes, Pedro; Leao, Tarcisio; Uebelhart, Beatriz; Fonseca, Jeison; Leme, Juliana; Utiyama, Bruno; da Silva, Cibele; Cavalheiro, Andre; Filho, Diolino Santos; Dinkhuysen, Jarbas; Biscegli, Jose; Andrade, Aron; Arruda, Celso

    2011-05-01

    An implantable centrifugal blood pump has been developed with original features for a left ventricular assist device. This pump is part of a multicenter and international study with the objective to offer simple, affordable, and reliable devices to developing countries. Previous computational fluid dynamics investigations and wear evaluation in bearing system were performed followed by prototyping and in vitro tests. In addition, previous blood tests for assessment of normalized index of hemolysis show results of 0.0054±2.46 × 10⁻³ mg/100 L. An electromechanical actuator was tested in order to define the best motor topology and controller configuration. Three different topologies of brushless direct current motor (BLDCM) were analyzed. An electronic driver was tested in different situations, and the BLDCM had its mechanical properties tested in a dynamometer. Prior to evaluation of performance during in vivo animal studies, anatomical studies were necessary to achieve the best configuration and cannulation for left ventricular assistance. The results were considered satisfactory, and the next step is to test the performance of the device in vivo.

  16. Fluid dynamic design and analysis of a highly loaded Centrifugal rotor for mini orc power systems

    NARCIS (Netherlands)

    Vitale, S.; Pini, M.; Ghidoni, A.; Colonna di Paliano, P.

    2015-01-01

    Organic Rankine Cycle (ORC) power systems are a well-established technology for the conversion of thermal energy sources in the small-to-medium power range. In the last few years, efforts have been devoted to the development of mini ORC (mORC) power systems (5- 30 kWe) for waste heat recovery from t

  17. Centrifugal LabTube platform for fully automated DNA purification and LAMP amplification based on an integrated, low-cost heating system.

    Science.gov (United States)

    Hoehl, Melanie M; Weißert, Michael; Dannenberg, Arne; Nesch, Thomas; Paust, Nils; von Stetten, Felix; Zengerle, Roland; Slocum, Alexander H; Steigert, Juergen

    2014-06-01

    This paper introduces a disposable battery-driven heating system for loop-mediated isothermal DNA amplification (LAMP) inside a centrifugally-driven DNA purification platform (LabTube). We demonstrate LabTube-based fully automated DNA purification of as low as 100 cell-equivalents of verotoxin-producing Escherichia coli (VTEC) in water, milk and apple juice in a laboratory centrifuge, followed by integrated and automated LAMP amplification with a reduction of hands-on time from 45 to 1 min. The heating system consists of two parallel SMD thick film resistors and a NTC as heating and temperature sensing elements. They are driven by a 3 V battery and controlled by a microcontroller. The LAMP reagents are stored in the elution chamber and the amplification starts immediately after the eluate is purged into the chamber. The LabTube, including a microcontroller-based heating system, demonstrates contamination-free and automated sample-to-answer nucleic acid testing within a laboratory centrifuge. The heating system can be easily parallelized within one LabTube and it is deployable for a variety of heating and electrical applications.

  18. Centrifugal pumps for rocket engines

    Science.gov (United States)

    Campbell, W. E.; Farquhar, J.

    1974-01-01

    The use of centrifugal pumps for rocket engines is described in terms of general requirements of operational and planned systems. Hydrodynamic and mechanical design considerations and techniques and test procedures are summarized. Some of the pump development experiences, in terms of both problems and solutions, are highlighted.

  19. 自适应离心式机械摩擦阻尼传动系统设计%Design of Adaptive Centrifugal Mechanical Friction Damp Transmission System

    Institute of Scientific and Technical Information of China (English)

    陈明

    2012-01-01

    设计了一种自适应离心式机械摩擦阻尼传动系统.该系统主要是利用离心力随转速变化的运动特性实现机械传动装置输出运动的自适应速度控制.整套系统由齿轮传动组、离心轮、弹簧发条、钢丝滚筒四部分组成,着重对前三部分进行了设计计算与分析,并最终完成样机试制.通过对样机进行自适应速度测试试验,获得了摩擦阻力矩随滚筒转速变化的特征曲线,为离心式机械摩擦阻尼系统的设计提供理论上的技术参考,同时也为实现机械传动装置输出运动的自适应控制提供了一条新的设计思路.%Adaptive centrifugal of mechanical friction damp transmission system is designed, by using the character about centrifugal changing with velocity, adaptive velocity control function of mechanical transmission system is realized. The whole system includes gear transmission,clockwork spring,steel roller and centrifugal wheel, two front configurations are designed and calculated specially, the prototype is produced. Finally, experiment is carried out to get character curve of damp force changing with velocity, a technical supports for centrifugal friction damp system and a new thought for realizing adaptive control of mechanic transmission equipment are provided.

  20. PVC干燥离心母液系统改造%Improvement of centrifugal mother liquid system of PVC drying equipment

    Institute of Scientific and Technical Information of China (English)

    王智廷; 朱立国; 巩清明

    2012-01-01

    Based on the improvement of centrifugal mother liquid system, ensure the equipment running stably in a long period ,to reduce the repairing and operation works ,the economic profit was developed.%通过对离心母液系统改造,保证了设备长周期稳定运行,减少了维修及工艺操作工作量,创造了经济效益。

  1. Energy-saving control model of inverter for centrifugal pump systems

    Directory of Open Access Journals (Sweden)

    Yin Luo

    2015-06-01

    Full Text Available The inverter control strategy is the key to pump energy-saving operation and should be established based on the current system configurations and system requirements, which is not the case in practice. As a result, the characteristics of pump system requirements and a combination pump with inverter were studied, and the mathematical models were established. A new model for an optimal inverter control strategy based on the current system configurations and system requirements was then established, and a method combining golden section search and genetic algorithm was formulated to solve this optimal model. This model sets up an optimal inverter control strategy to increase the efficiency of pump operation following a process line near the minimum requirements to improve operation conditions. The implementation difficulty of the control law was also reduced. Finally, the optimized model was applied to an industrial circulating pump system, and the result showed that the model can not only determine the optimal inverter control strategy but also evaluate the current operation situation of the pump configuration and determine the energy-saving potential for the current configuration, which can aid in the subsequent energy-saving reconstruction.

  2. Solar gas turbine systems with centrifugal particle receivers, for remote power generation

    OpenAIRE

    Prosin, Tobias; Pryor, Trevor; Creagh, Christine; Amsbeck, Lars; Uhlig, Ralf

    2015-01-01

    There is a growing demand from remote communities in Australia to increase the amount of decentralised renewable energy in their energy supply mix in order to decrease their fuel costs. In contrast to large scale concentrated solar power (CSP) plants, small solar-hybrid gas turbine systems promise a way to decentralise electricity generation at power levels in the range of 0.1- 10 MWe, and reduce to cost of energy production for off-grid, isolated communities. Thermal storage provides such...

  3. Expert system for the diagnosis of the condition and performance of centrifugal pumps

    Energy Technology Data Exchange (ETDEWEB)

    Jantunen, E.; Vaehae-Pietilae, K.; Pesonen, K. [Technical Research Centre of Finland, Manufacturing Technology, Espoo (Finland)

    1997-12-31

    A brief description of the results of a study concerning the maintenance and downtime costs in Finnish pumping is given. The leakage of seals was found to be the fault that causes the highest downtime and maintenance costs. A small laboratory arrangement has been used to test the effectiveness of various condition monitoring methods. This information has been used in the development of a diagnostic expert system called CEPDIA, which can be used for diagnosing the condition of a pump and its components. The diagnosis is based on measuring results obtained from sensors and on information about maintenance actions carried out with the pump and its components. The principles of the CEPDIA expert system are described. A database is included in the system for handling and saving the measurement results, technical information on the pumps and maintenance actions carried out with the pumps. The diagnosis can also be based on vibration signature analysis, which is quite effective in determining which fault is the actual cause of malfunction of the pump or its components. CEPDIA can also be used to calculate of the efficiency of the electrical motor and the pump. CEPDIA has been tested in the diagnosis of 63 pumps. The average efficiency in pumping was less than 40 %, and more than 10 % of the pumps were pumping with less than 10 % efficiency. (orig.) 11 refs.

  4. Centrifugal innervation of the mammalian olfactory bulb.

    Science.gov (United States)

    Matsutani, Shinji; Yamamoto, Noboru

    2008-12-01

    Although it has been known for decades that the mammalian olfactory bulb receives a substantial number of centrifugal inputs from other regions of the brain, relatively few data have been available on the function of the centrifugal olfactory system. Knowing the role of the centrifugal projection and how it works is of critical importance to fully understanding olfaction. The centrifugal fibers can be classified into two groups, a group that release neuromodulators, such as noradrenaline, serotonin, or acetylcholine, and a group originating in the olfactory cortex. Accumulating evidence suggests that centrifugal neuromodulatory inputs are associated with acquisition of odor memory. Because the distribution of the terminals on these fibers is diffuse and widespread, the neuromodulatory inputs must affect diverse subsets of bulbar neurons at the same time. In contrast, knowledge of the role of centrifugal fibers from the olfactory cortical areas is limited. Judging from recent morphological evidence, these fibers may modify the activity of neurons located in sparse and discrete loci in the olfactory bulb. Given the modular organization of the olfactory bulb, centrifugal fibers from the olfactory cortex may help coordinate the activities of restricted subsets of neurons belonging to distinct functional modules in an odor-specific manner. Because the olfactory cortex receives inputs from limbic and neocortical areas in addition to inputs from the bulb, the centrifugal inputs from the cortex can modulate odor processing in the bulb in response to non-olfactory as well as olfactory cues.

  5. 离心泵机组中惯性飞轮装置的设计%Design of Inertia Flywheel in Centrifugal Pump System

    Institute of Scientific and Technical Information of China (English)

    汪永海

    2015-01-01

    对于离心泵作为冷却系统中的供液泵,在突然断电导致原动机失去动力的情况下,需要离心泵可以延时运转一段时间,并继续保持有一定的冷却液体输出,而常规的离心泵由于叶轮惯性相对较小,一旦原动机失去动力,离心泵会在液体的阻力作用下迅速停止;通过在离心泵机组中增加惯性飞轮作为储能装置,在原动机断电时,储能装置为离心泵提供动力,以实现延时运转并保持一定的液体输出,确保被冷却设备在突然断电时可以得到延时冷却,从而保护设备,并增加整个系统的处理时间。%For a centrifugal pump used in cooling system ,it needs the centrifugal pump keep running in the case of power outage,and continue pumping the liquid,but the ordinary centrifugal pump will stop very fast when power outage happened because of the small inertia of pump impeller. In order to keep the pump running after the power outage we add the inertia flywheel to the pump system. Inertia flywheel as an energy storage device can supply energy to the centrifugal pump when power outage happened, so that can drive the pump impeller running and pumping the liquid to protect the machine.

  6. Microfluidic Integration of a Cloth-Based Hybridization Array System (CHAS) for Rapid, Colorimetric Detection of Enterohemorrhagic Escherichia coli (EHEC) Using an Articulated, Centrifugal Platform.

    Science.gov (United States)

    Geissler, Matthias; Clime, Liviu; Hoa, Xuyen D; Morton, Keith J; Hébert, Harold; Poncelet, Lucas; Mounier, Maxence; Deschênes, Mylène; Gauthier, Martine E; Huszczynski, George; Corneau, Nathalie; Blais, Burton W; Veres, Teodor

    2015-10-20

    We describe the translation of a cloth-based hybridization array system (CHAS), a colorimetric DNA detection method that is used by food inspection laboratories for colony screening of pathogenic agents, onto a microfluidic chip format. We also introduce an articulated centrifugal platform with a novel fluid manipulation concept based on changes in the orientation of the chip with respect to the centrifugal force field to time the passage of multiple components required for the process. The platform features two movable and motorized carriers that can be reoriented on demand between 0 and 360° during stage rotation. Articulation of the chip can be used to trigger on-the-fly fluid dispensing through independently addressable siphon structures or to relocate solutions against the centrifugal force field, making them newly accessible for downstream transfer. With the microfluidic CHAS, we achieved significant reduction in the size of the cloth substrate as well as the volume of reagents and wash solutions. Both the chip design and the operational protocol were optimized to perform the entire process in a reliable, fully automated fashion. A demonstration with PCR-amplified genomic DNA confirms on-chip detection and identification of Escherichia coli O157:H7 from colony isolates in a colorimetric multiplex assay using rfbO157, fliCH7, vt1, and vt2 genes.

  7. Investigation of Embedded Si/C System Exposed to a Hybrid Reaction of Centrifugal-Assisted Thermite Method.

    Directory of Open Access Journals (Sweden)

    Reza Mahmoodian

    Full Text Available A novel method is proposed to study the behavior and phase formation of a Si+C compacted pellet under centrifugal acceleration in a hybrid reaction. Si+C as elemental mixture in the form of a pellet is embedded in a centrifugal tube. The pellet assembly and tube are exposed to the sudden thermal energy of a thermite reaction resulted in a hybrid reaction. The hybrid reaction of thermite and Si+C produced unique phases. X-ray diffraction pattern (XRD as well as microstructural and elemental analyses are then investigated. XRD pattern showed formation of materials with possible electronic and magnetic properties. The cooling rate and the molten particle viscosity mathematical model of the process are meant to assist in understanding the physical and chemical phenomena took place during and after reaction. The results analysis revealed that up to 85% of materials converted into secondary products as ceramics-matrix composite.

  8. Investigation of Embedded Si/C System Exposed to a Hybrid Reaction of Centrifugal-Assisted Thermite Method.

    Science.gov (United States)

    Mahmoodian, Reza; Yahya, Rosiyah; Dabbagh, Ali; Hamdi, Mohd; Hassan, Mohsen A

    2015-01-01

    A novel method is proposed to study the behavior and phase formation of a Si+C compacted pellet under centrifugal acceleration in a hybrid reaction. Si+C as elemental mixture in the form of a pellet is embedded in a centrifugal tube. The pellet assembly and tube are exposed to the sudden thermal energy of a thermite reaction resulted in a hybrid reaction. The hybrid reaction of thermite and Si+C produced unique phases. X-ray diffraction pattern (XRD) as well as microstructural and elemental analyses are then investigated. XRD pattern showed formation of materials with possible electronic and magnetic properties. The cooling rate and the molten particle viscosity mathematical model of the process are meant to assist in understanding the physical and chemical phenomena took place during and after reaction. The results analysis revealed that up to 85% of materials converted into secondary products as ceramics-matrix composite. PMID:26641651

  9. Design of a centrifugal blood pump: Heart Turcica Centrifugal.

    Science.gov (United States)

    Demir, Onur; Biyikli, Emre; Lazoglu, Ismail; Kucukaksu, Suha

    2011-07-01

    A prototype of a new implantable centrifugal blood pump system named Heart Turcica Centrifugal (HTC) was developed as a left ventricular assist device (LVAD) for the treatment of end-stage cardiac failure. In the development of HTC, effects of blade height and volute tongue profiles on the hydraulic and hemolytic performances of the pump were investigated. As a result, the prototype was manufactured using the best blade height and volute tongue profiles. Performance of the prototype model was experimentally evaluated in a closed-loop flow system using water as the medium. The hydraulic performance requirement of an LVAD (5 L/min flow rate against a pressure difference of 100 mm Hg) was attained at 2800 rpm rotational speed.

  10. Fault Detection and Isolation in Centrifugal Pumps

    DEFF Research Database (Denmark)

    Kallesøe, Carsten

    Centrifugal pumps are used in a variety of different applications, such as water supply, wastewater, and different industrial applications. Some pump installations are crucial for the applications to work. Failures can lead to substantial economic losses and can influence the life of many people...... is placed. The topic of this work is Fault Detection and Identification in centrifugal pumps. Different approaches are developed with special focus on robustness. Robustness with respect to disturbances, unknown parts of the system, and parameter variations are considered. All developed algorithms...... are tested on an industrial test setup, showing the usability of the algorithms on a real centrifugal pump....

  11. Centrifugal pump handbook

    CERN Document Server

    Pumps, Sulzer

    2010-01-01

    This long-awaited new edition is the complete reference for engineers and designers working on pump design and development or using centrifugal pumps in the field. This authoritative guide has been developed with access to the technical expertise of the leading centrifugal pump developer, Sulzer Pumps. In addition to providing the most comprehensive centrifugal pump theory and design reference with detailed material on cavitation, erosion, selection of materials, rotor vibration behavior and forces acting on pumps, the handbook also covers key pumping applications topics and operational

  12. Centrifuge pellet injector for JET

    International Nuclear Information System (INIS)

    An engineering design of a centrifuge pellet injector for JET is reported as part of the Phase I contract number JE 2/9016. A rather detailed design is presented for the mechanical and electronic features. Stress calculations, dynamic behaviour and life estimates are considered. The interfaces to the JET vacuum system and CODAS are discussed. Proposals for the pellet diagnostics (velocity, mass and shape) are presented. (orig.)

  13. Experimental Measurements of Drop Size Distributions in 30 mm Diameter Annular Centrifugal Contactor with 30% TBP-Nitric Acid Biphasic System

    Directory of Open Access Journals (Sweden)

    Shekhar Kumar

    2013-01-01

    Full Text Available For design and development of liquid-liquid extraction systems, it is essential to have an accurate estimation of hydrodynamic and mass transfer characteristics of the employed contactor. In the present study, experimental evaluations consisted primarily of determining the maximum solution throughput that could be processed without cross-phase contamination at a given rotor speed, O/A flow ratio, and organic-aqueous solution pair in a 30 mm bowl diameter centrifugal contactor. In addition, analysis included experimental drop size determinations as well as holdup determination. The experimental drop size distributions are expected to be helpful for modeling work.

  14. DESIGN INFORMATION REPORT: CENTRIFUGES

    Science.gov (United States)

    In the 1960s, manufacturers began to design centrifuges specifically for wastewater sludge applications. In addition, sludge thickening and dewatering processes were improved with the introduction of polyelectrolytes for chemical sludge conditioning. The report contains a brief d...

  15. Effects of centrifugation on gonadal and adrenocortical steroids in rats

    Science.gov (United States)

    Kakihana, R.; Butte, J. C.

    1980-01-01

    Many endocrine systems are sensitive to external changes in the environment. Both the pituitary adrenal and pituitary gonadal systems are affected by stress including centrifugation stress. The effect of centrifugation on the pituitary gonadal and pituitary adrenocortical systems was examined by measuring the gonadal and adrenal steroids in the plasma and brain following different duration and intensity of centrifugation stress in rats. Two studies were completed and the results are presented. The second study was carried out to describe the developmental changes of brain, plasma and testicular testosterone and dihydrotestosterone in Sprague Dawley rats so that the effect of centrifugation stress on the pituitary gonadal syatem could be better evaluated in future studies.

  16. Geotechnical Centrifuge Studies of Unsaturated Transport

    Science.gov (United States)

    Smith, R. W.; Mattson, E. D.; Palmer, C. D.

    2007-12-01

    Improved understanding of contaminant migration in heterogeneous, variably saturated porous media is required to better define the long-term stewardship requirements for U.S. Department of Energy (DOE) lands and to assist in the design of effective vadose-zone barriers to contaminant migrations. A geotechnical centrifuge provides an experimental approach to explore vadose zone transport over a wide range of relevant conditions in time frames not possible for conventional bench-top experiments. Our research to date resulted in the design, construction, and testing of in-flight experimental apparatus allowing the replication of traditional bench top unsaturated transport experiments using the 2-meter radius geotechnical centrifuge capabilities at the Idaho National Laboratory. Additionally we conducted a series of unsaturated 1-dimenstional column experiments using conservative tracers to evaluate the effects of increased centrifugal acceleration on derived transport properties and assessing the scaling relationships for these properties. Our experimental results indicated that breakthrough times for a conservative tracer decreased significantly and systematically as a function of increased centrifugal acceleration. Differences between these experimental results and estimates based on predictive scaling rules are due to slight moisture content differences between experiments at different centrifugal accelerations. In contrast, dispersion coefficients varied systemically with centrifugal acceleration in accordance with predictive scaling rules. The results we obtained in this study indicate that the centrifuge technique is a viable experimental method for the study of subsurface processes where gravitational acceleration is important. The geotechnical centrifuge allows experiments to be completed more quickly than tests conducted at 1-gravity and can be used to experimentally address important scaling issues, and permits experiments under a range of conditions that

  17. Separation of uranium isotopes by gas centrifugation

    International Nuclear Information System (INIS)

    The uranium isotope enrichment is studied by means of the countercurrent gas centrifuge driven by thermal convection. A description is given of (a) the transfer and purification of the uranium hexafluoride used as process gas in the present investigation; (b) the countercurrent centrifuge ZG3; (c) the system designed for the introduction and extraction of the process gas from the centrifuge; (d) the measurement of the process gas flow rate through the centrifuge; (e) the determination of the uranium isotopic abundance by mass spectrometry; (f) the operation and mechanical behavior of the centrifuge and (g) the isotope separation experiments, performed, respectively, at total reflux and with production of enriched material. The results from the separation experiments at total reflux are discussed in terms of the enrichment factor variation with the magnitude and flow profile of the countercurrent given by the temperature difference between the rotor covers. As far as the separation experiments with production are concerned, the discussion of their results is presented through the variation of the enrichment factor as a function of the flow rate, the observed asymmetry of the process and the calculated separative power of the centrifuge. (Author)

  18. Geotechnical centrifuge under construction

    Science.gov (United States)

    Richman, Barbara T.

    Modifications are underway at the National Aeronautics and Space Administration (NASA) Ames Research Center in California to transform a centrifuge used in the Apollo space program to the largest geotechnical centrifuge in the free world. The centrifuge, to be finished in August and opened next January, following check out and tuning, will enable geoscientists to model stratigraphic features down to 275 m below the earth's surface. Scientists will be able to model processes that are coupled with body force loading, including earthquake response of earth structures and soil structure interaction; rubbled-bed behavior during in situ coal gasification or in oil shale in situ retorts; behavior of frozen soil; frost heave; behavior of offshore structures; wave-seabed interactions; explosive cratering; and blast-induced liquefaction.The centrifuge will have a load capacity of 900-g-tons (short); that is, it will be able to carry a net soil load of 3 short tons to a centripetal acceleration of 300 times the acceleration caused by gravity. Modified for a total cost of $2.4 million, the centrifuge will have an arm with a 7.6-m radius and a swinging platform or bucket at its end that will be able to carry a payload container measuring 2.1×2.1 m. An additional future input of $500,000 would enable the purchase of a larger bucket that could accommodate a load of up to 20 tons, according to Charles Babendreier, program director for geotechnical engineering at the National Science Foundation. Additional cooling for the motor would also be required. The centrifuge has the capability of accelerating the 20-ton load to 100 g.

  19. Perceived radial translation during centrifugation

    NARCIS (Netherlands)

    Bos, J.E.; Correia Grácio, B.J.

    2015-01-01

    BACKGROUND: Linear acceleration generally gives rise to translation perception. Centripetal acceleration during centrifugation, however, has never been reported giving rise to a radial, inward translation perception. OBJECTIVE: To study whether centrifugation can induce a radial translation percepti

  20. A Review of Biomedical Centrifugal Microfluidic Platforms

    Directory of Open Access Journals (Sweden)

    Minghui Tang

    2016-02-01

    Full Text Available Centrifugal microfluidic or lab-on-a-disc platforms have many advantages over other microfluidic systems. These advantages include a minimal amount of instrumentation, the efficient removal of any disturbing bubbles or residual volumes, and inherently available density-based sample transportation and separation. Centrifugal microfluidic devices applied to biomedical analysis and point-of-care diagnostics have been extensively promoted recently. This paper presents an up-to-date overview of these devices. The development of biomedical centrifugal microfluidic platforms essentially covers two categories: (i unit operations that perform specific functionalities, and (ii systems that aim to address certain biomedical applications. With the aim to provide a comprehensive representation of current development in this field, this review summarizes progress in both categories. The advanced unit operations implemented for biological processing include mixing, valving, switching, metering and sequential loading. Depending on the type of sample to be used in the system, biomedical applications are classified into four groups: nucleic acid analysis, blood analysis, immunoassays, and other biomedical applications. Our overview of advanced unit operations also includes the basic concepts and mechanisms involved in centrifugal microfluidics, while on the other hand an outline on reported applications clarifies how an assembly of unit operations enables efficient implementation of various types of complex assays. Lastly, challenges and potential for future development of biomedical centrifugal microfluidic devices are discussed.

  1. Assessment of hydraulic performance and biocompatibility of a MagLev centrifugal pump system designed for pediatric cardiac or cardiopulmonary support.

    Science.gov (United States)

    Dasse, Kurt A; Gellman, Barry; Kameneva, Marina V; Woolley, Joshua R; Johnson, Carl A; Gempp, Thomas; Marks, John D; Kent, Stella; Koert, Andrew; Richardson, J Scott; Franklin, Steve; Snyder, Trevor A; Wearden, Peter; Wagner, William R; Gilbert, Richard J; Borovetz, Harvey S

    2007-01-01

    The treatment of children with life-threatening cardiac and cardiopulmonary failure is a large and underappreciated public health concern. We have previously shown that the CentriMag is a magnetically levitated centrifugal pump system, having the utility for treating adults and large children (1,500 utilized worldwide). We present here the PediVAS, a pump system whose design was modified from the CentriMag to meet the physiological requirements of young pediatric and neonatal patients. The PediVAS is comprised of a single-use centrifugal blood pump, reusable motor, and console, and is suitable for right ventricular assist device (RVAD), left ventricular assist device (LVAD), biventricular assist device (BVAD), or extracorporeal membrane oxygenator (ECMO) applications. It is designed to operate without bearings, seals and valves, and without regions of blood stasis, friction, or wear. The PediVAS pump is compatible with the CentriMag hardware, although the priming volume was reduced from 31 to 14 ml, and the port size reduced from 3/8 to (1/4) in. For the expected range of pediatric flow (0.3-3.0 L/min), the PediVAS exhibited superior hydraulic efficiency compared with the CentriMag. The PediVAS was evaluated in 14 pediatric animals for up to 30 days, demonstrating acceptable hydraulic function and hemocompatibility. The current results substantiate the performance and biocompatibility of the PediVAS cardiac assist system and are likely to support initiation of a US clinical trial in the future. PMID:18043164

  2. Central centrifugal cicatricial alopecia

    OpenAIRE

    Collin Blattner; Dennis C Polley; Frank Ferritto; Elston, Dirk M

    2013-01-01

    Central centrifugal cicatricial alopecia is a common cause of progressive permanent apical alopecia. This unique form of alopecia includes entities previously know as “hot comb alopecia,” “follicular degeneration syndrome,” “pseudopelade” in African Americans and “central elliptical pseudopelade” in Caucasians. The etiology appears to be multifactorial and the condition occurs in all races.

  3. Centrifugal atomisation of alloys

    Energy Technology Data Exchange (ETDEWEB)

    Li Huiping [School of Mechanical and Materials Engineering, Univ. of Surrey, Guilford (United Kingdom); Dept. of Inorganic Materials, East China Univ. of Science and Technology, Shanghai, SH (China); Tsakiropoulos, P. [School of Mechanical and Materials Engineering, Univ. of Surrey, Guilford (United Kingdom); Johnson, T. [Tetronics Ltd., Faringdon, Oxfordshire (United Kingdom)

    2001-07-01

    Centrifugal atomisation using a rotating disk is described and compared to REP and PREP. Results of calculations of models describing the interaction of a melt with a rotating disk, the formation of thin film on the disk and the break up of the thin film and its atomisation at the edge of the disk are compared with experimental results. (orig.)

  4. Pulsatile compared with nonpulsatile perfusion using a centrifugal pump for cardiopulmonary bypass during coronary artery bypass grafting. Effects on systemic haemodynamics, oxygenation, and inflammatory response parameters.

    Science.gov (United States)

    Driessen, J J; Dhaese, H; Fransen, G; Verrelst, P; Rondelez, L; Gevaert, L; van Becelaere, M; Schelstraete, E

    1995-01-01

    The present study investigated the influence of pulsatile or nonpulsatile flow delivery with a centrifugal pump for cardiopulmonary bypass (CPB) during coronary artery bypass grafting (CABG) in two randomized groups of 19 patients each. All patients received a standard anaesthetic and surgical protocol. Pulsatile perfusion during CPB was created by accelerating the baseline pump speed of the Sarns centrifugal pump at a rate of 50 cycles per minute. Measurements included perioperative systemic haemodynamics and oxygen exchange, total haemolytic complement (CH50), polymorphonuclear (neutrophil) granulocyte (PMN) count and plasma granulocyte elastase bound to alpha 1-proteinase inhibitor (E-alpha 1-PI). Laboratory measurements were corrected for haemodilution. During and after CPB there were only a few significant differences between the groups in systemic haemodynamics and oxygenation, i.e. a lower mean arterial blood pressure after the end of CPB in the nonpulsatile group (65 mmHg, SD = 11 vs 76 mmHg, SD = 11) and a lower SvO2 during rewarming on CPB in the nonpulsatile group (62%, SD = 8 vs 67%, SD = 8). The decrease in percentage of PMNs in the total white blood cell count during CPB was greater in the nonpulsatile group than in the pulsatile group (from 61 to 46% vs 63 to 53% of prebypass value). The steep increase of PMN count at the end of CPB and postoperatively was comparable in both groups. The maximal decrease of CH50 levels, occurring after surgery, was significantly higher in the nonpulsatile group (70% SD = 15 vs 79%, SD = 16, of baseline value), suggesting a greater complement activation. E-alpha 1-PI levels increased significantly in both groups during and after CPB with higher peak levels, obtained at one hour after admission to an intensive care unit, in the nonpulsatile group (316 micrograms/l, SD = 102) than in the pulsatile group (247 micrograms/l, SD = 106). There was a partly inverse correlation between the peak postoperative elastase levels and

  5. Detection methods for centrifugal microfluidic platforms.

    Science.gov (United States)

    Burger, Robert; Amato, Letizia; Boisen, Anja

    2016-02-15

    Centrifugal microfluidics has attracted much interest from academia as well as industry, since it potentially offers solutions for affordable, user-friendly and portable biosensing. A wide range of so-called fluidic unit operations, e.g. mixing, metering, liquid routing, and particle separation, have been developed and allow automation and integration of complex assay protocols in lab-on-a-disc systems. Besides liquid handling, the detection strategy for reading out the assay is crucial for developing a fully integrated system. In this review, we focus on biosensors and readout methods for the centrifugal microfluidics platform and cover optical as well as mechanical and electrical detection principles.

  6. Performance in Centrifugal Compressors

    Directory of Open Access Journals (Sweden)

    K. Sato

    1999-01-01

    Full Text Available A 3-D unsteady thin-layer Navier-Stokes code has been used to calculate the flow through a centrifugal compressor stage. The validation of the code for steady flows in centrifugal compressors was conducted for the Krain’s impeller with a vaneless diffuser as a test case and the numerical results were compared with the experimental results. The predicted flow field and performance agreed well with the experimental data. An unsteady stage solution was then conducted with this impeller followed by a generic low-solidity vaned-diffuser to examine the unsteady effects on the impeller performance. The computational results showed a stabilising effect of the blade row interaction.

  7. Phase system selection with fractional factorial design for purification of recombinant cyanovirin-N from a hydroponic culture medium using centrifugal partition chromatography.

    Science.gov (United States)

    Grudzień, Łukasz; Madeira, Luisa; Fisher, Derek; Ma, Julian; Garrard, Ian

    2013-04-12

    Centrifugal partition chromatography (CPC) with an aqueous two-phase system (ATPS) was used to purify recombinant cyanovirin-N (CV-N) from other proteins which were co-secreted into a hydroponic plant medium in a rhizosecretion process. To achieve satisfactory protein concentration, the purification was preceded by ultrafiltration performed on a 5 kDa filter. ATPS, because of their gentle nature, were selected as the phase system for CPC. A systematic phase system selection was applied. This involved studying the effect of seven parameters of ATPS: polymer type, salt type, the polymer and salt concentration, the polymer molecular weight, pH, and presence of two additional salts; NaCl and NaClO4, which all together gave 320 combinations. design of experiment (DoE) software allowed the reduction of this number to 46. Having tested partitioning of cyanovirin-N and impurities in 46 ATPS, the three best potential phase systems generated by the programme were then tested on the CPC. Out of these three, 13/13% PEG4000 sodium phosphate, pH 3.0, proved to be most effective phase system in the purification of cyanovirin-N, judged by ELISA and SDS-PAGE analysis, as it eliminated most of the impurities from the final cyanovirin-N preparation.

  8. Analysis of Secondary Flows in Centrifugal Impellers

    Directory of Open Access Journals (Sweden)

    Brun Klaus

    2005-01-01

    Full Text Available Secondary flows are undesirable in centrifugal compressors as they are a direct cause for flow (head losses, create nonuniform meridional flow profiles, potentially induce flow separation/stall, and contribute to impeller flow slip; that is, secondary flows negatively affect the compressor performance. A model based on the vorticity equation for a rotating system was developed to determine the streamwise vorticity from the normal and binormal vorticity components (which are known from the meridional flow profile. Using the streamwise vorticity results and the small shear-large disturbance flow method, the onset, direction, and magnitude of circulatory secondary flows in a shrouded centrifugal impeller can be predicted. This model is also used to estimate head losses due to secondary flows in a centrifugal flow impeller. The described method can be employed early in the design process to develop impeller flow shapes that intrinsically reduce secondary flows rather than using disruptive elements such as splitter vanes to accomplish this task.

  9. Gas Centrifuges and Nuclear Proliferation

    Energy Technology Data Exchange (ETDEWEB)

    Albright, David

    2004-09-15

    Gas centrifuges have been an ideal enrichment method for a wide variety of countries. Many countries have built gas centrifuges to make enriched uranium for peaceful nuclear purposes. Other countries have secretly sought centrifuges to make highly enriched uranium for nuclear weapons. In more recent times, several countries have secretly sought or built gas centrifuges in regions of tension. The main countries that have been of interest in the last two decades have been Pakistan, Iraq, Iran, and North Korea. Currently, most attention is focused on Iran, Pakistan, and North Korea. These states did not have the indigenous abilities to make gas centrifuges, focusing instead on illicit and questionable foreign procurement. The presentation covered the following main sections: Spread of centrifuges through illicit procurement; Role of export controls in stopping proliferation; Increasing the transparency of gas centrifuge programs in non-nuclear weapon states; and, Verified dismantlement of gas centrifuge programs. Gas centrifuges are important providers of low enriched uranium for civil nuclear power reactors. They also pose special nuclear proliferation risks. We all have special responsibilities to prevent the spread of gas centrifuges into regions of tension and to mitigate the consequences of their spread into the Middle East, South Asia, and North Asia.

  10. Study of centrifugal compressor dynamic pressure test system based on LabVIEW%基于 LabVIEW的离心压缩机动态压力测试系统研究

    Institute of Scientific and Technical Information of China (English)

    李杰; 王航; 刘宁; 程凯

    2015-01-01

    从分析表征离心压缩机喘振发生时的动态压力特性入手,揭示离心压缩机的出、入口及叶轮处的动态压力信号对研究压缩机喘振主动控制的重要意义。随后在800 kW离心压缩机系统上设计了动态压力测量的NI测试系统,并用LabVIEW进行软件开发和实现。为致力于研究离心压缩机系统特性、喘振机理及主动控制方法的工程技术人员提供了搭建测试系统的设计原则和实现方法,具有重要的参考价值。%Surge of centrifugal compressor is the unsteady flow process, the effective parameters of dynamic pressure characteristic of this process is analyzed.This illustrates that measurement and analysis of the dynamic pressure signal of centrifugal compressor at the exit, entrance and impeller is of great sig-nificance to study the active control of compressor surge.Then the NI test system is designed based on the 800 kW centrifugal compressor, which is suitable for the measurement of dynamic pressure of centrifugal compressor, and the software carried out by the LabVIEW.This paper provides the design principles of constructing test research and implementation method of the system for engineers and technicians, who committed to the research of system characteristics of centrifugal compressor, surge mechanism and active control method of surge.

  11. 模拟自然风风机控制系统设计%Design of Centrifugal Fan Control System for Natural Wind Simulation

    Institute of Scientific and Technical Information of China (English)

    杨义强; 付晶; 宋仲康; 汤馥源; 陈怡

    2016-01-01

    为了检验旋翼无人机巡检系统抗风能力,搭建抗风试验场模拟自然风. 重点阐述了敞开式风场环境中风机与风管控制机构参数计算过程、模拟自然风方法及风速控制算法. 仿真验证了风速控制算法的合理性,并简述了嵌入式控制器作为试验场控制装置的优点及其设计方法. 通过该设计实现了检验旋翼无人机巡检系统抗风能力高低的目的.%In order to examine the wind resistance ability of the rotorcraft Uav inspection system, the wind resistance test e-quipment was designed to simulate the natural wind.This article introduces the centrifugal fan system and the construction of duct and its control device, then the methods to simulate the natural wind and the wind-speed control arithmetics were studied.In the following part, it described the rationality of control arithmetics depend on the simulation results.Finally, the reason to choose the embedded controller and its design were illustrated.All the above combined to the wind resistance test equipment.

  12. Centrifugal-reciprocating compressor

    Science.gov (United States)

    Higa, W. H. (Inventor)

    1984-01-01

    A centrifugal compressor is described which includes at least one pair of cylinders arranged in coaxial alignment and supported for angular displacement about a common axis of rotation normally disecting a common longitudinal axis of symmetry for the cylinders. The cylinders are characterized by ported closures located at the mutually remote ends thereof through which the cylinders are charged and discharged, and a pair of piston heads seated within the cylinders and supported for floating displacement in compressive strokes in response to unidirectional angular displacement imparted to the cylinders.

  13. Centrifugal bucket hoist

    OpenAIRE

    Kotačka, Petr

    2014-01-01

    This bachelor thesis deals with an engineering design of a centrifugal bucket elevator with transport height 6.5 metres and transport performance 40 000 kilograms per hour. The thesis focuses especially on a functional calculation of the elevator thanks to which a gear motor, band and bucket are chosen. This is followed by an analysis of a constructional solution with a strength check of a drive shaft and parallel keys as well as a calculation of a service life of bearings. Technical document...

  14. Centrifugal membrane filtration - Task 9

    International Nuclear Information System (INIS)

    The Energy and Environmental Research Center (EERC) has teamed with SpinTek Membrane Systems, Inc., the developer of a centrifugal membrane filtration technology, to demonstrate applications for the SpinTek technology within the US Department of Energy (DOE) Environmental management (EM) Program. The technology uses supported microporous membranes rotating at high rpm, under pressure, to separate suspended and colloidal solids from liquid streams, yielding a solids-free permeate stream and a highly concentrated solids stream. This is a crosscutting technology that falls under the Efficient Separations and Processing Crosscutting Program, with potential application to tank wastes, contaminated groundwater, landfill leachate, and secondary liquid waste streams from other remediation processes, including decontamination and decommissioning systems. Membrane-screening tests were performed with the SpinTek STC-X4 static test cell filtration unit, using five ceramic membranes with different pore size and composition. Based on permeate flux, a 0.25-microm TiO2/Al2O3 membrane was selected for detailed performance evaluation using the SpinTek ST-IIL centrifugal membrane filtration unit with a surrogate tank waste solution. An extended test run of 100 hr performed on a surrogate tank waste solution showed some deterioration in filtration performance, based on flux, apparently due to the buildup of solids near the inner portion of the membrane where relative membrane velocities were low. Continued testing of the system will focus on modifications to the shear pattern across the entire membrane surface to affect improved long-term performance

  15. Centrifugal membrane filtration -- Task 9

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-08-01

    The Energy and Environmental Research Center (EERC) has teamed with SpinTek Membrane Systems, Inc., the developer of a centrifugal membrane filtration technology, to demonstrate applications for the SpinTek technology within the US Department of Energy (DOE) Environmental management (EM) Program. The technology uses supported microporous membranes rotating at high rpm, under pressure, to separate suspended and colloidal solids from liquid streams, yielding a solids-free permeate stream and a highly concentrated solids stream. This is a crosscutting technology that falls under the Efficient Separations and Processing Crosscutting Program, with potential application to tank wastes, contaminated groundwater, landfill leachate, and secondary liquid waste streams from other remediation processes, including decontamination and decommissioning systems. Membrane-screening tests were performed with the SpinTek STC-X4 static test cell filtration unit, using five ceramic membranes with different pore size and composition. Based on permeate flux, a 0.25-{micro}m TiO{sub 2}/Al{sub 2}O{sub 3} membrane was selected for detailed performance evaluation using the SpinTek ST-IIL centrifugal membrane filtration unit with a surrogate tank waste solution. An extended test run of 100 hr performed on a surrogate tank waste solution showed some deterioration in filtration performance, based on flux, apparently due to the buildup of solids near the inner portion of the membrane where relative membrane velocities were low. Continued testing of the system will focus on modifications to the shear pattern across the entire membrane surface to affect improved long-term performance.

  16. Differential white cell count by centrifugal microfluidics.

    Energy Technology Data Exchange (ETDEWEB)

    Sommer, Gregory Jon; Tentori, Augusto M.; Schaff, Ulrich Y.

    2010-07-01

    We present a method for counting white blood cells that is uniquely compatible with centrifugation based microfluidics. Blood is deposited on top of one or more layers of density media within a microfluidic disk. Spinning the disk causes the cell populations within whole blood to settle through the media, reaching an equilibrium based on the density of each cell type. Separation and fluorescence measurement of cell types stained with a DNA dye is demonstrated using this technique. The integrated signal from bands of fluorescent microspheres is shown to be proportional to their initial concentration in suspension. Among the current generation of medical diagnostics are devices based on the principle of centrifuging a CD sized disk functionalized with microfluidics. These portable 'lab on a disk' devices are capable of conducting multiple assays directly from a blood sample, embodied by platforms developed by Gyros, Samsung, and Abaxis. [1,2] However, no centrifugal platform to date includes a differential white blood cell count, which is an important metric complimentary to diagnostic assays. Measuring the differential white blood cell count (the relative fraction of granulocytes, lymphocytes, and monocytes) is a standard medical diagnostic technique useful for identifying sepsis, leukemia, AIDS, radiation exposure, and a host of other conditions that affect the immune system. Several methods exist for measuring the relative white blood cell count including flow cytometry, electrical impedance, and visual identification from a stained drop of blood under a microscope. However, none of these methods is easily incorporated into a centrifugal microfluidic diagnostic platform.

  17. Performance of a Centrifugal Slurry Pump

    Directory of Open Access Journals (Sweden)

    Hawas Yahya Bajawi

    2014-02-01

    Full Text Available The aim of this study was to experimentally investigate the effect of speed, concentration and size of slurry on the performance of a centrifugal pump. For this purpose a facility was built where the performance of a centrifugal slurry pump was examined using aggregate slurry. Three sizes of slurry with three concentrations and at three impeller speeds were used for the performance investigations of a centrifugal slurry pump. As a reference performance the performance of centrifugal slurry pump was also tested with clean water. The performance of pump has been reported as variations of head, power and efficiency at various flow rates along with the system characteristics of the pump. The results reveal that the pump performance is grossly affected by the type of slurry, its concentration and size. Besides this the variation in speed also affects the performance as is observed in pumps with water. The maximum decrease in the head, with respect to clear water, at the operating point was found to be 47% for aggregate for size 20 mm, 15% concentration and 2600 rpm. The maximum decrement in efficiency at operating point for aggregate was found to be 47% for 4 mm size, 15% concentration and at 2200 rpm. The power increment requirement for aggregate was 9% for 4 mm size, 15% concentration and 2600 rpm.

  18. Unshrouded Centrifugal Turbopump Impeller

    Science.gov (United States)

    Prueger, George; Williams, Morgan; Chen, Wei; Paris, John; Stewart, Eric; Williams, Robert

    1999-01-01

    The ratio of rocket engine thrust to weight is a limiting constraint in placing more payload into orbit at a low cost. A key component of an engine's overall weight is the turbopump weight, Reducing the turbopump weight can result in significant engine weight reduction and hence, increased delivered payload. There are two main types of pumps: centrifugal and axial pumps. These types of pumps can be further sub-divided into those with shrouds and those without shrouds (unshrouded pumps). Centrifugal pumps can achieve the same pump discharge pressure as an axial pump and it requires fewer pump stages and lower pump weight than an axial pump. Also, with unshrouded centrifugal pumps (impeller), the number of stages and weight can be further reduced. However. there are several issues with regard to using an unshrouded impeller: 1) there is a pump performance penalty due to the front open face recirculation flow; 2) there is a potential pump axial thrust problem from the unbalanced front open face and the back shroud face; and, 3) since test data is very linu'ted for this configuration, there is uncertainty in the magnitude and phase of the rotordynamics forces due to the front impeller passage. The purpose of the paper is to discuss the design of an unshrouded impeller and to examine the design's hydrodynamic performance, axial thrust, and rotordynamics performance. The design methodology will also be discussed. This work will help provide some guidelines for unshrouded impeller design. In particular, the paper will discuss the design of three unshrouded impellers - one with 5 full and 5 partial blades (5+5). one with 6+6 blades and one with 8+8 blades. One of these designs will be selected for actual fabrication and flow test. Computational fluid dynamics (CFD) is used to help design and optimize the unshrouded impeller. The relative pump performance penalty is assessed by comparing the CFD results of the unshrouded impeller with the equivalent shrouded impeller for a

  19. Research on the Energy Consumption Evaluation and Energy Saving Technical Reconstruction of Centrifugal Pump System Based on Actual Demand

    OpenAIRE

    Luo Yin; Shouqi Yuan; Tang Yue; Yuan Jianping

    2013-01-01

    A new method for calculating the operational efficiency of a pumping station has been developed based on the integral principle and operation rules of the pump flow rate. To determine the energy saving space of a pumping system and to reflect the relationship between supply and demand, a new method for evaluating the energy consumption rate of a pump system has been developed based on the principle of an inverter-controlled water supply with varying pressures. These methods have been applied ...

  20. [Galileo and centrifugal force].

    Science.gov (United States)

    Vilain, Christiane

    This work intends to focus on Galileo's study of what is now called "centrifugal force," within the framework of the Second Day of his Dialogo written in 1632, rather than on the previously published commentaries on the topic. Galileo proposes three geometrical demonstrations in order to prove that gravity will always overcome centrifugalforce, and that the potential rotation of the Earth, whatever its speed, cannot in any case project objects beyond it. Each of these demonstrations must consequently contain an error and it has seemed to us that the first one had not been understood up until now. Our analysis offers an opportunity to return to Galileo's geometrical representation of dynamical questions; actually, we get an insight into the sophistication of Galileo's practices more than into his mistakes. Our second point, concerning the historiography of the problem, shows an evolution from anachronic critics to more contextual considerations, in the course of the second half of the twentieth century.

  1. [Galileo and centrifugal force].

    Science.gov (United States)

    Vilain, Christiane

    This work intends to focus on Galileo's study of what is now called "centrifugal force," within the framework of the Second Day of his Dialogo written in 1632, rather than on the previously published commentaries on the topic. Galileo proposes three geometrical demonstrations in order to prove that gravity will always overcome centrifugalforce, and that the potential rotation of the Earth, whatever its speed, cannot in any case project objects beyond it. Each of these demonstrations must consequently contain an error and it has seemed to us that the first one had not been understood up until now. Our analysis offers an opportunity to return to Galileo's geometrical representation of dynamical questions; actually, we get an insight into the sophistication of Galileo's practices more than into his mistakes. Our second point, concerning the historiography of the problem, shows an evolution from anachronic critics to more contextual considerations, in the course of the second half of the twentieth century. PMID:25029818

  2. Development of the Seeding System Used for Laser Velocimeter Surveys of the NASA Low-Speed Centrifugal Compressor Flow Field

    Science.gov (United States)

    Wasserbauer, C. A.; Hathaway, M. D.

    1994-01-01

    Consideration is given to an atomizer-based system for distributing high-volume rates of polystyrene latex (PSL) seed material developed to support laser velocimeter investigations of the NASA Low-Speed Compressor flow field. Complete evaporation of the liquid carrier before the flow entering the compressor was of primary concern for the seeder system design. It is argued that the seed nozzle should incorporate a needle valve that can mechanically dislodge accumulated PSL seed material when the nozzle is turned off. Water is less expensive as the liquid carrier and should be used whenever adequate residence times are available to ensure complete evaporation. PSL agglomerates over time and needs to be mixed or blended before use. Arrangement of the spray nozzles needs to be adjustable to provide maximum seeding at the laser probe volume.

  3. High stability design for new centrifugal compressor

    Science.gov (United States)

    Kanki, H.; Katayama, K.; Morii, S.; Mouri, Y.; Umemura, S.; Ozawa, U.; Oda, T.

    1989-01-01

    It is essential that high-performance centrifugal compressors be free of subsynchronous vibrations. A new high-performance centrifugal compressor has been developed by applying the latest rotordynamics knowledge and design techniques: (1) To improve the system damping, a specially designed oil film seal was developed. This seal attained a damping ratio three times that of the conventional design. The oil film seal contains a special damper ring in the seal cartridge. (2) To reduce the destabilizing effect of the labyrinth seal, a special swirl canceler (anti-swirl nozzle) was applied to the balance piston seal. (3) To confirm the system damping margin, the dynamic simulation rotor model test and the full load test applied the vibration exciting test in actual load conditions.

  4. Condensing Heat Recovery of Centrifugal Chiller

    Institute of Scientific and Technical Information of China (English)

    GONG Guang-cai; JIAO Jun-jun; WANG Li-ping; ZENG Wei

    2009-01-01

    To a kind of centrifugal water chiUer with R22 and about 1745 kW of cooling capacity.a heat exchanger was added between the outlet of compressor and original condenser to get part of or all the condensing heat.Condensing heat can be recovered by compound condensing method,which adopts air-cooling model+wa-ter-cooling model or water-cooling model+water-cooling model at the condensing side of the system.By exergy analysis and experiment research on compound condensing heat recovery of centrifugal chiller,the results are ob-tained that the capability of the whole system increases,the energy efficiency ratio (EER) becomes 3.2~5.0 from 2.2~3.4, which implies the EER increases about 1.0~1.5,the exergy efficiency increases about 10%,and the chiller runs more stably after reformation.

  5. Centrifugal compressor design choices for chillers

    Energy Technology Data Exchange (ETDEWEB)

    Brasz, J.J. [United Technologies Carrier, New York, NY (United States)

    1999-07-01

    The use of centrifugal compressors in the air conditioning and refrigeration industry is currently limited to large water cooled chillers varying in size from about 0.5 to 6 MW cooling capacity. These systems are primarily used for comfort or process cooling applications. All systems try to chill relatively large amounts of indoor or process water by a few degrees Celsius in a refrigerant evaporator. The heat removed from the chilled water is released together with the heat of compression in a refrigerant condenser to cooling tower water, from where it is discharged to the atmosphere. Different centrifugal compressor design concepts are used by the various chiller manufacturers: single-stage versus multi-stage, vaneless versus vaned diffuser, hermetic versus open-drive motors, shrouded versus open impellers, fixed versus variable diffuser geometry, low- versus high-pressure refrigerant. This variability seems strange for a mature industry like the air conditioning and refrigeration industry. This paper will show that the reason for this variability is the product compromise between the various conflicting system requirements with respect to size, cost, efficiency and refrigerant choice. The different system applications of the chillers (e.g. comfort cooling in a equatorial region versus process cooling in a moderate climate zone) play another major role in selecting an optimal centrifugal compression concept. Some general recommendations will be given for applications where a clear choice can be made. (Author)

  6. Centrifugal shot blasting. Innovative technology summary report

    Energy Technology Data Exchange (ETDEWEB)

    1999-07-01

    At the US Department of Energy (DOE) Fernald Environmental Management Project (FEMP), the Facilities Closure and Demolition Projects Integrated Remedial Design/Remedial Action (RD/RA) work plan calls for the removal of one inch (1 in) depth of concrete surface in areas where contamination with technetium-99 has been identified. This report describes a comparative demonstration between two concrete removal technologies: an innovative system using Centrifugal Shot Blasting (CSB) and a modified baseline technology called a rotary drum planer.

  7. Centrifugal shot blasting. Innovative technology summary report

    International Nuclear Information System (INIS)

    At the US Department of Energy (DOE) Fernald Environmental Management Project (FEMP), the Facilities Closure and Demolition Projects Integrated Remedial Design/Remedial Action (RD/RA) work plan calls for the removal of one inch (1 in) depth of concrete surface in areas where contamination with technetium-99 has been identified. This report describes a comparative demonstration between two concrete removal technologies: an innovative system using Centrifugal Shot Blasting (CSB) and a modified baseline technology called a rotary drum planer

  8. Microwave assisted centrifuge and related methods

    Science.gov (United States)

    Meikrantz, David H [Idaho Falls, ID

    2010-08-17

    Centrifuge samples may be exposed to microwave energy to heat the samples during centrifugation and to promote separation of the different components or constituents of the samples using a centrifuge device configured for generating microwave energy and directing the microwave energy at a sample located in the centrifuge.

  9. Analysis of the reliability of the centrifugal pumping system on the Northeast pole platforms in the Campos basin; Analise de confiabilidade do sistema de bombeio centrifugo das plataformas do polo nordeste da bacia de Campos

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Luiz; Bardy, Mariana [Principia Engenharia de Informatica, Salvador, BA (Brazil); Simoes Filho, Salvador [PETROBRAS, Rio de Janeiro, RJ (Brazil). Centro de Pesquisas (CENPES). Div. de Engenharia Basica Industrial; Neves, Edinei [PETROBRAS, Campos, RJ (Brazil). Exploracao e Producao

    1999-12-01

    The results of the statistical analysis of useful life data for the Submersible Centrifugal Pumping (BCS) sets installed in the wells in the Northeast Pole of the Campos Basin are given in this work. The objective is to analyze the data compiled with a view to determine the failure rate distributions for the various system components. These are important for the reliability analysis of the BCS systems and to predict the expected number of equipment acquisitions over a yearly period. In addition, suggestions are made aimed at improving the operational reliability of the systems analyzed. (author)

  10. Uranium enrichment by gas centrifuge

    International Nuclear Information System (INIS)

    After recalling the physical principles and the techniques of centrifuge enrichment the report describes the centrifuge enrichment programmes of the various countries concerned and compares this technology with other enrichment technologies like gaseous diffusion, laser, aerodynamic devices and chemical processes. The centrifuge enrichment process is said to be able to replace with advantage the existing enrichment facilities in the short and medium term. Future prospects of the process are also described, like recycled uranium enrichment and economic improvements; research and development needs to achieve the economic prospects are also indicated. Finally the report takes note of the positive aspect of centrifuge enrichment as far as safeguards and nuclear safety are concerned. 27 figs, 113 refs

  11. CALCULATION AND IMPROVEMENT OF DYNAMIC CHARACTERISTICS OF CENTRIFUGE

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The modeling of the rotor-support system of a typical centrifuge is discussed. The impedance matching method, cooperating with Riccati transfer matrix method and modal analysis method are adopted to calculate its dynamic characteristics. The influences of the main parts to the critical speeds are analyzed. Based on the analysis, a critical speed in the operating speed range is tuned successfully, and thus the dynamic characteristics of the centrifuge are much improved.

  12. Design and Characterization of a Centrifugal Compressor Surge Test Rig

    OpenAIRE

    Kin Tien Lim; Se Young Yoon; Christopher P. Goyne; Zongli Lin; Allaire, Paul E.

    2011-01-01

    A detailed description of a new centrifugal compressor surge test rig is presented. The objective of the design and development of the rig is to study the surge phenomenon in centrifugal compression systems and to investigate a novel method of surge control by active magnetic bearing servo actuation of the impeller axial tip clearance. In this paper, we focus on the design, initial setup, and testing of the rig. The latter two include the commissioning of the rig and the experimental characte...

  13. Gas centrifugal separator

    International Nuclear Information System (INIS)

    Object: To enhance separating performance by jointly using separating action of impulse wave without increasing peripheral speed of a gas centrifugal separator and lengthening a cylindrical portion thereof. Structure: A mixed gas is introduced into a rotating cylinder from a mixed gas pipe and is separated into gas rich in light component and gas decreased in light component, these gases being taken outside the rotating cylinder through a product opening and a fixed waste pipe, respectively. A fixed product recycling pipe is disposed between an upper end plate and an upper buffer plate of the rotating cylinder the recycling pipe having an opening formed at the leading end so as to oppose to the rotating mixed gas, and the gas introduced from the opening is re-introduced into the central portion of the rotating cylinder for recirculation. A waste pipe is disposed between a lower end plate and a lower buffer plate of the rotating cylinder, and the gas not introduced into the opening of the waste pipe is circulated within the rotating cylinder. (Kamimura, M.)

  14. A vibration model for centrifugal contactors

    Energy Technology Data Exchange (ETDEWEB)

    Leonard, R.A.; Wasserman, M.O.; Wygmans, D.G.

    1992-11-01

    Using the transfer matrix method, we created the Excel worksheet ``Beam`` for analyzing vibrations in centrifugal contactors. With this worksheet, a user can calculate the first natural frequency of the motor/rotor system for a centrifugal contactor. We determined a typical value for the bearing stiffness (k{sub B}) of a motor after measuring the k{sub B} value for three different motors. The k{sub B} value is an important parameter in this model, but it is not normally available for motors. The assumptions that we made in creating the Beam worksheet were verified by comparing the calculated results with those from a VAX computer program, BEAM IV. The Beam worksheet was applied to several contactor designs for which we have experimental data and found to work well.

  15. Vibration analysis of large centrifugal pump rotors

    Science.gov (United States)

    Y Zhao, W.; Ge, J. G.; Ma, D.; Li, C. M.; Bao, S. B.

    2013-12-01

    Through the critical speed of centrifugal pumps, internal flow field and the force of the impeller, we analyze centrifugal pump vibration. Using finite element analysis software ANSYS to calculate the natural frequency of the rotor system and the critical speed; with the help of the Fluent software to simulate pump internal flow field, we conclude that speed increase will not cause intense vibration of the fluid in the pump. Using unsteady numerical simulation we discovered that in an impeller suffering transient radial force cyclical change periodically, as well as the frequency size determined by the product of the impeller speed and number of blades, resonance phenomena should make impeller to transient radial force frequency. If wanting to avoid pump resonance when it is running away, the transient radial force frequency should avoid the frequency range which can cause resonance.

  16. Vibration analysis of large centrifugal pump rotors

    International Nuclear Information System (INIS)

    Through the critical speed of centrifugal pumps, internal flow field and the force of the impeller, we analyze centrifugal pump vibration. Using finite element analysis software ANSYS to calculate the natural frequency of the rotor system and the critical speed; with the help of the Fluent software to simulate pump internal flow field, we conclude that speed increase will not cause intense vibration of the fluid in the pump. Using unsteady numerical simulation we discovered that in an impeller suffering transient radial force cyclical change periodically, as well as the frequency size determined by the product of the impeller speed and number of blades, resonance phenomena should make impeller to transient radial force frequency. If wanting to avoid pump resonance when it is running away, the transient radial force frequency should avoid the frequency range which can cause resonance

  17. Fluent-based numerical simulation of flow centrifugal fan

    Institute of Scientific and Technical Information of China (English)

    LI Xian-zhang

    2011-01-01

    Testing centrifugal fan flow field by physical laboratory is difficult because the testing system is complex and the workload is heavy, and the results observed by naked-eye deviates far from the actual value. To address this problem, the computational fluid dynamics software FLUENT was applied to establish three-dimensional model of the centrifugal fan. The numeral model was verified by comparing simulation data to experimental data. The pressure centrifugal fan and the speed changes in distribution in centrifugal fan was simulated by computational fluid dynamics software FLUENT. The simulation results show that the gas flow velocity in the impeller increases with impeller radius increase. Static pressure gradually increases when gas from the fan access is imported through fan impeller leaving fans.

  18. Hyperbolically Shaped Centrifugal Compressor

    Institute of Scientific and Technical Information of China (English)

    Romuald Puzyrewski; Pawel Flaszy(n)ski

    2003-01-01

    Starting from the classical centrifugal compressor, cone shaped in meridional cross section, two modifications are considered on the basis of results from 2D and 3D flow models. The first modification is the change of the meridional cross section to hyperbolically shaped channel. The second modification, proposed on the basis of 2D axisymmetric solution, concerns the shape of blading. On the strength of this solution the blades are formed as 3D shaped blades, coinciding with the recent tendency in 3D designs. Two aims were considered for the change of meridional compressor shape. The first was to remove the separation zone which appears as the flow tums from axial to radial direction. The second aim is to uniformize the flow at exit of impeller. These two goals were considered within the frame of 2D axisymmetric model. Replacing the cone shaped compressor by a hyperbolically shaped one, the separation at the corner was removed. The disc and shroud shape of the compressor was chosen in the way which satisfies the condition of most uniform flow at the compressor exit. The uniformity of exit flow from the rotor can be considered as the factor which influences the performance of the diffuser following the rotor. In the 2D model a family of stream surfaces of S1 type is given in order to find S2 surfaces which may be identified with the midblade surfaces of compressor blading. A computation of 3D type has been performed in order to establish the relations between 2D and 3D models in the calculation of flow parameters. In the presented example the 2D model appears as the inverse model which leads to 3D shape of blading whereas the 3D model has been used for the direct solution. In the presented example the confrontation of two models, 2D and 3D, leads to a better understanding of the application of these models to the design procedure.

  19. Centrifugation. A theoretical study of oxygen enrichment by centrifugation

    Energy Technology Data Exchange (ETDEWEB)

    Kierkegaard, P.; Raetz, E.

    1998-12-01

    In the present paper we first investigate what happens if we fill a cylinder with air, close it and rotate it. The results show that no matter which peripheral speed is used, it is not possible by means of the radial separation effect alone, to enrich the oxygen concentration from the previous 21% to more then 23.3%, which is of no practical value. In case of a too low enrichment in one centrifuge, the wanted material from this centrifuge can be used as an input for a second centrifuge and so on, in this way forming a cascade of centrifuges. Oxygen will be enriched in each step, until the desired concentration is reached. Cascading was the technology in the very beginning by enrichment plants for uraniumhexaflouride, used for atomic weapons and nuclear power plants. In this study we try to avoid cascading by aiming for higher separation factors. Therefore, we next investigate the possibilities of using a countercurrent centrifuge where in principle the enriched gas is subjected to several centrifugation in the same centrifuge. The calculations show, that in this way it is possible to produce nearly a 100% pure oxygen (polluted with some heavier molecules like argon) in one machine. Our third step was to calculate the amount of oxygen produced per hour. Using a countercurrent centrifuge of the Zippe type, 100 cm high and 20 cm in diameter, it is or will be possible in the near future to produce 17 g enriched air per hour enriched to 50% oxygen. That corresponds to processing 1 m{sup 3} atmospherical air in the period of approximately 24 hours. This is not very impressive. Our fourth step was to estimate the amount of power used for producing this amount of oxygen. A rough, but complicated, estimate shows that the power consumption at the production level will be about the double of the consumption used today. The overall conclusion is, that centrifugation as a production method for oxygen (or nitrogen) will not be competitive with the currently used method in the

  20. EM Task 9 - Centrifugal Membrane Filtration

    International Nuclear Information System (INIS)

    This project is designed to establish the utility of a novel centrifugal membrane filtration technology for the remediation of liquid mixed waste streams at US Department of Energy (DOE) facilities in support of the DOE Environmental Management (EM) program. The Energy and Environmental Research Center (EERC) has teamed with SpinTek Membrane Systems, Inc., a small business and owner of the novel centrifugal membrane filtration technology, to establish the applicability of the technology to DOE site remediation and the commercial viability of the technology for liquid mixed waste stream remediation. The technology is a uniquely configured process that makes use of ultrafiltration and centrifugal force to separate suspended and dissolved solids from liquid waste streams, producing a filtered water stream and a low-volume contaminated concentrate stream. This technology has the potential for effective and efficient waste volume minimization, the treatment of liquid tank wastes, the remediation of contaminated groundwater plumes, and the treatment of secondary liquid waste streams from other remediation processes, as well as the liquid waste stream generated during decontamination and decommissioning activities

  1. Centrifugal microfluidic platforms: advanced unit operations and applications.

    Science.gov (United States)

    Strohmeier, O; Keller, M; Schwemmer, F; Zehnle, S; Mark, D; von Stetten, F; Zengerle, R; Paust, N

    2015-10-01

    Centrifugal microfluidics has evolved into a mature technology. Several major diagnostic companies either have products on the market or are currently evaluating centrifugal microfluidics for product development. The fields of application are widespread and include clinical chemistry, immunodiagnostics and protein analysis, cell handling, molecular diagnostics, as well as food, water, and soil analysis. Nevertheless, new fluidic functions and applications that expand the possibilities of centrifugal microfluidics are being introduced at a high pace. In this review, we first present an up-to-date comprehensive overview of centrifugal microfluidic unit operations. Then, we introduce the term "process chain" to review how these unit operations can be combined for the automation of laboratory workflows. Such aggregation of basic functionalities enables efficient fluidic design at a higher level of integration. Furthermore, we analyze how novel, ground-breaking unit operations may foster the integration of more complex applications. Among these are the storage of pneumatic energy to realize complex switching sequences or to pump liquids radially inward, as well as the complete pre-storage and release of reagents. In this context, centrifugal microfluidics provides major advantages over other microfluidic actuation principles: the pulse-free inertial liquid propulsion provided by centrifugal microfluidics allows for closed fluidic systems that are free of any interfaces to external pumps. Processed volumes are easily scalable from nanoliters to milliliters. Volume forces can be adjusted by rotation and thus, even for very small volumes, surface forces may easily be overcome in the centrifugal gravity field which enables the efficient separation of nanoliter volumes from channels, chambers or sensor matrixes as well as the removal of any disturbing bubbles. In summary, centrifugal microfluidics takes advantage of a comprehensive set of fluidic unit operations such as

  2. Deep eutectic solvents in countercurrent and centrifugal partition chromatography.

    Science.gov (United States)

    Roehrer, Simon; Bezold, Franziska; García, Eva Marra; Minceva, Mirjana

    2016-02-19

    Deep eutectic solvents (DESs) were evaluated as solvents in centrifugal partition chromatography, a liquid-liquid chromatography separation technology. To this end, the partition coefficients of ten natural compounds of different hydrophobicity were determined in non-aqueous biphasic systems containing DES. The influence of the composition of DESs and the presence of water in the biphasic system on the partition coefficient were also examined. In addition, several process relevant physical properties of the biphasic system, such as the density and viscosity of the phases, were measured. A mixture of three to four hydrophobic compounds was successfully separated in a centrifugal partition extractor using a heptane/ethanol/DES biphasic system.

  3. Deep eutectic solvents in countercurrent and centrifugal partition chromatography.

    Science.gov (United States)

    Roehrer, Simon; Bezold, Franziska; García, Eva Marra; Minceva, Mirjana

    2016-02-19

    Deep eutectic solvents (DESs) were evaluated as solvents in centrifugal partition chromatography, a liquid-liquid chromatography separation technology. To this end, the partition coefficients of ten natural compounds of different hydrophobicity were determined in non-aqueous biphasic systems containing DES. The influence of the composition of DESs and the presence of water in the biphasic system on the partition coefficient were also examined. In addition, several process relevant physical properties of the biphasic system, such as the density and viscosity of the phases, were measured. A mixture of three to four hydrophobic compounds was successfully separated in a centrifugal partition extractor using a heptane/ethanol/DES biphasic system. PMID:26810802

  4. The Dynamics of Stall and Surge Behavior in Axial-Centrifugal Compressors

    OpenAIRE

    Cousins, William T.

    1997-01-01

    The phenomena of stall and surge in axial-centrifugal compressors is investigated through high-response measurements of both the pressure field and the flowfield throughout the surge cycle. A unique high-response forward-facing and aft-facing probe provides flow information. Several axial-centrifugal compressors are examined, both in compressor rigs and engines. Extensive discussion is presented on the differences in axial and centrifugal rotors and their effect on the system response char...

  5. Centrifugation and the Manhattan Project

    Science.gov (United States)

    Reed, Cameron

    2009-05-01

    A study of U. S. Army Manhattan Engineer District documents reveals that consideration of centrifugation as a means of uranium enrichment during World War II was considerably more extensive than is commonly appreciated. By the time the centrifuge project was abandoned in early 1944 a full-scale prototype unit had been fabricated and tested at near-production speeds, enrichments of close to theoretically-expected levels had been demonstrated with pilot-plant units, and plans for production plants had been developed. This paper will review the history of this little-known aspect of the Project and examine the circumstances of how it came to be discontinued.

  6. Control and Data Acquisition System for R500B Biaxial Centrifuge Shaker%R500B大型土工离心机双向振动台控制及数据采集系统

    Institute of Scientific and Technical Information of China (English)

    宋献慧; 侯瑜京; 梁建辉

    2012-01-01

    介绍了中国水利水电科学研究院建成的大型土工离心机双向(水平+垂直)振动台控制和数据采集系统,介绍了系统采用控制软件的基本功能、控制原理,以及操作程序等.目前已成功实现了在高速旋转的离心机中进行振动台的控制和数据采集,但随着各类不同试验的具体要求,系统功能仍需要进一步开发和完善.%The authors introduce the control and data acquisition system for the R500B biaxial (horizontal and vertical) shaker table of the IWHR (China Institute of Water Resources and Hydropower Research) Geotechnical Centrifuge. The control theory, the function of the software and the working procedures of the system are presented in this paper. This system has been successfully operated at 80 g centrifugal acceleration, and is needed to be improved to meet different requirements of experiments in the future.

  7. Enriched surface acidity for surfactant-free suspensions of carboxylated carbon nanotubes purified by centrifugation

    Directory of Open Access Journals (Sweden)

    Elizabeth I. Braun

    2016-06-01

    Full Text Available It is well known that surfactant-suspended carbon nanotube (CNT samples can be purified by centrifugation to decrease agglomerates and increase individually-dispersed CNTs. However, centrifugation is not always part of protocols to prepare CNT samples used in biomedical applications. Herein, using carboxylated multi-walled CNTs (cMWCNTs suspended in water without a surfactant, we developed a Boehm titrimetric method for the analysis of centrifuged cMWCNT suspensions and used it to show that the surface acidity of oxidized carbon materials in aqueous cMWCNT suspensions was enriched by ∼40% by a single low-speed centrifugation step. This significant difference in surface acidity between un-centrifuged and centrifuged cMWCNT suspensions has not been previously appreciated and is important because the degree of surface acidity is known to affect the interactions of cMWCNTs with biological systems.

  8. Empirical Design Considerations for Industrial Centrifugal Compressors

    OpenAIRE

    Cheng Xu; Amano, Ryoichi S.

    2012-01-01

    Computational Fluid Dynamics (CFD) has been extensively used in centrifugal compressor design. CFD provides further optimisation opportunities for the compressor design rather than designing the centrifugal compressor. The experience-based design process still plays an important role for new compressor developments. The wide variety of design subjects represents a very complex design world for centrifugal compressor designers. Therefore, some basic information for centrifugal design is still ...

  9. Performance of a Centrifugal Slurry Pump

    OpenAIRE

    Hawas Yahya Bajawi; Basharat Salim; Ziyadh Suhibani

    2014-01-01

    The aim of this study was to experimentally investigate the effect of speed, concentration and size of slurry on the performance of a centrifugal pump. For this purpose a facility was built where the performance of a centrifugal slurry pump was examined using aggregate slurry. Three sizes of slurry with three concentrations and at three impeller speeds were used for the performance investigations of a centrifugal slurry pump. As a reference performance the performance of centrifugal slurry pu...

  10. Continuous-Flow Centrifugal Separator

    Science.gov (United States)

    Waldron, Robert D.

    1988-01-01

    Apparatus combines principles of centrifugal and cyclone separators to control movement of solid or liquid particles suspended in flowing gas. Spinning disk contains radial channels, width varys as function of distance from center. Gas flows from outer ring around disk toward center. Particles in gas collected at periphery, center or both.

  11. Laser and gas centrifuge enrichment

    Energy Technology Data Exchange (ETDEWEB)

    Heinonen, Olli [Senior Fellow, Belfer Center for Science and International Affairs, Harvard Kennedy School, Cambridge, Massachusetts (United States)

    2014-05-09

    Principles of uranium isotope enrichment using various laser and gas centrifuge techniques are briefly discussed. Examples on production of high enriched uranium are given. Concerns regarding the possibility of using low end technologies to produce weapons grade uranium are explained. Based on current assessments commercial enrichment services are able to cover the global needs of enriched uranium in the foreseeable future.

  12. Laser and gas centrifuge enrichment

    Science.gov (United States)

    Heinonen, Olli

    2014-05-01

    Principles of uranium isotope enrichment using various laser and gas centrifuge techniques are briefly discussed. Examples on production of high enriched uranium are given. Concerns regarding the possibility of using low end technologies to produce weapons grade uranium are explained. Based on current assessments commercial enrichment services are able to cover the global needs of enriched uranium in the foreseeable future.

  13. Evaluation of two new filtration systems--Fenwal PS400 and Organon Teknika Curesis--and comparison of results with two centrifugation systems--IBM model 2997 and Haemonetics V50.

    Science.gov (United States)

    Coffe, C; Couteret, Y; Pujol, J P; Kieffer, Y; Lenys, R; Panouse, J; Peters, A

    1985-07-01

    Two new filtration systems (Fenwal CPS 10TM - PS 400 and Organon Teknika Curesis - M82) were evaluated and compared with two centrifugal cell separators (IBM 2997 and Haemonetics V50). 11 patients with auto immune diseases and dermatological diseases underwent 230 consecutive plasma exchanges. For the filtration systems, the average whole blood rate was 50 ml/min and the plasma separation rate was about 21 ml/min for a transmembrane pressure about 70 mmHg. The pre/post percent reduction and sieving coefficient were calculated for some plasma and blood components. A variety of laboratory studies was monitored to assess the efficacy of plasma separators, their biocompatibility and some yields. These results show that the 2 filters appear safe and efficacious but their modules are too simple and do not offer a great security (no transmembrane pressure control or no extracorporeal fluid balance). For a blood banker, IBM 2997 seems more interesting if we take in account its characteristics during plasma exchanges and the possibility which is offered to carry out cytapheresis procedures. But for a thrombopenic patient the filtration systems keep their advantages.

  14. A fuzzy controlled three-phase centrifuge for waste separation

    International Nuclear Information System (INIS)

    The three-phase centrifuge technology discussed in this paper was developed by Neal Miller, president of Centech, Inc. The three-phase centrifuge is an excellent device for cleaning up oil field and refinery wastes which are typically composed of hydrocarbons, water, and solids. The technology is unique. It turns the waste into salable oil, reusable water, and landfill-able solids. No secondary waste is produced. The problem is that only the inventor can set up and run the equipment well enough to provide an optimal cleanup. Demand for this device has far exceeded a one man operation. There is now a need for several centrifuges to be operated at different locations at the same time. This has produced a demand for an intelligent control system, one that could replace a highly skilled operator, or at least supplement the skills of a less experienced operator. The control problem is ideally suited to fuzzy logic, since the centrifuge is a highly complicated machine operated entirely by the skill and experience of the operator. A fuzzy control system was designed for and used with the centrifuge

  15. Open-cycle centrifugal vapor-compression heat pump

    Science.gov (United States)

    Burgmeier, L. R.; Horner, J. E.

    1987-11-01

    The objectives of the program were: (1) to develop an open cycle, high lift, centrifugal steam compressor system that can be efficiently retrofitted to existing multi-effect and high temperature differential evaporators while maintaining the cost benefits of a single stage centrifugal compressor, and (2) to demonstrate the energy saving cost benefits of driving the compressor with a natural gas fueled gas turbine engine. The turbine exhaust was to be used for final drying of the product that was evaporated. The installation of the system is described along with the test activities through May 1987.

  16. Parametric performance evaluation of a hydraulic centrifugal pump

    Science.gov (United States)

    Heo, M. W.; Y Kim, K.; Ma, S. B.; Yoo, I. S.; Choi, W. C.; Kim, J. H.; Choi, Y. S.

    2014-03-01

    Parametric study of a hydraulic centrifugal pump with backward curved blades has been performed numerically using three-dimensional Reynolds-averaged Navier-Stokes equations. The shear stress transport turbulence model was used for analysis of turbulence. The finite volume method and an unstructured grid system were used for the numerical solution. The optimal grid system in the computational domain was selected through a grid dependency test. Tested parameters were related to the geometry of the impeller and volute: seven variables defining the hub and shroud contours and the blades angle of impeller, and two variables defining the inlet width and expansion angle of volute. The effects of these parameters on the hydrodynamic performance of the centrifugal pump have been investigated. It was found that the centrifugal water pump with the twisted blades has the enhancing efficiency compared to the straight blades pump.

  17. 同步带传动在离心机配平系统中的应用与研究%Application and Research of Synchronous Belt Transmission in Trimming System of the Centrifuge

    Institute of Scientific and Technical Information of China (English)

    李心耀; 洪建忠; 蒋春梅; 陈磊

    2011-01-01

    In order to trim combined environmental test centrifuge accurately, the synchronous belt transmission is designed to move the trim block in two tensile belts. The synchronous belt transmission comprises motor- reducer,trapezoidal synchronous belt, small pulley, big pulleys and tensioners. The axial force and the moment of synchronous belt transmission are analyzed. The transmission precision is also researched. The results indicate that synchronous belt transmission can realize adjustment of trimming system of the centrifuge steadily and accurately.%为了实现综合环境试验离心机的精确配平,设计了同步带传动来实现配重块在两根拉力带上的同步移动.同步带传动由电机-减速器、梯形齿同步带、小带轮、大带轮和张紧轮等组成.分析了同步带传动的压轴力和力矩传递状况,研究了同步带的传动精度.结果表明:同步带传动能实现离心机配平系统的平稳、精确调整.

  18. [The analytical setting of rotary speed of centrifuge rotor and centrifugation time in chemical, biochemical and microbiological practice].

    Science.gov (United States)

    Zolotarev, K V

    2012-08-01

    The researchers happen to face with suspensions in their chemical, biochemical and microbiological practice. The suspensions are the disperse systems with solid dispersed phase and liquid dispersion medium and with dispersed phase particle size > 100 nm (10-7 m). Quite often the necessity occurs to separate solid particles from liquid. To use for this purpose the precipitation in gravitation field can make the process to progress too long. In this respect an effective mode is the precipitation in the field of centrifugal forces--the centrifugation. The rotary speed of centrifuge rotor and centrifugation time can be set analytically using regularities of general dynamics and hydrodynamics. To this effect, should be written and transformed the equation of First and Second Newton Laws for suspension particle being in the field of centrifugal forces and forces of resistance of liquid and vessel wall. The force of liquid resistance depends on particle motion condition in liquid. To determine the regimen the Archimedes and Reynolds numerical dimensionless criteria are to be applied. The article demonstrates the results of these transformations as analytical inverse ratio dependence of centrifugation time from rotary speed. The calculation of series of "rate-time" data permits to choose the optimal data pair on the assumption of centrifuge capacity and practical reasonability. The results of calculations are validated by actual experimental data hence the physical mathematical apparatus can be considered as effective one. The setting progress depends both from parameter (Reynolds criterion) and data series calculation. So, the most convenient way to apply this operation is the programming approach. The article proposes to use the program Microsoft Excel and VBA programming language for this purpose. The possibility to download the file from Internet to use it for fast solution is proposed. PMID:23097986

  19. Characteristics of centrifugal rapid contactor, (3)

    International Nuclear Information System (INIS)

    Organic solvent yields the degradation product as a result of irradiation, in the extraction process of spent fuel reprocessing. The development of a centrifugal rapid contactor is required for the reduction of the solvent degradation by shortening the contact time. The effects of fine solid particles were investigated with a SGN-Robatel LX-208N contactor, following the uranium extraction and re-extraction performance tests. It was found as the experimental result that the considerable quantity of solids accumulated in the rotor of the centrifugal contactor. As for this experimental apparatus, the flow diagram for the centrifugal rapid contactor and auxiliary apparatuses is shown, which are the same system used for the uranium extraction and re-extraction tests. The schematic diagram, the typical stage construction and fluid transfer path of the LX-208 contactor are illustrated. The main specifications of the LX-208 contactor are as follows: the internal diameter of a rotating bowl 200 mm, the material SUS 316, the number of stages 8, and the total hold-up volume of the contactor 1.8 l. Most tests were carried out with aqueous feed only, because white Alundum is easily deposited in the rotor, and the particle concentration in effluent stream becomes undetectable when organic and aqueous feeds are supplied simultaneously. As the experimental results, the correlation of Alundum concentration in effluent and running time, the effect of rotor speed on effluent stream concentration, the particle size distribution curves for No. 6000 and No. 8000 white Alundum, the effect of flow rate on effluent stream concentration and the effect of flow rate on particle size distribution for both No. 6000 and No. 8000 white Alundum are presented. (Nakai, Y.)

  20. EM Task 9 - Centrifugal membrane filtration

    International Nuclear Information System (INIS)

    The overall project consists of several integrated research phases related to the applicability, continued development, demonstration, and commercialization of the SpinTek centrifugal membrane filtration process. Work performed during this reporting period consisted of Phase 2 evaluation of the SpinTek centrifugal membrane filtration technology and Phase 3, Technology Partnering. During Phase 1 testing conducted at the EERC using the SpinTek ST-IIL unit operating on a surrogate tank waste, a solids cake developed on the membrane surface. The solids cake was observed where linear membrane velocities were less than 17.5 ft/s and reduced the unobstructed membrane surface area up to 25%, reducing overall filtration performance. The primary goal of the Phase 2 research effort was to enhance filtration performance through the development and testing of alternative turbulence promoter designs. The turbulence promoters were designed to generate a shear force across the entire membrane surface sufficient to maintain a self-cleaning membrane capability and improve filtration efficiency and long-term performance. Specific Phase 2 research activities included the following: System modifications to accommodate an 11-in.-diameter, two-disk rotating membrane assembly; Development and fabrication of alternative turbulence promoter designs; Testing and evaluation of the existing and alternative turbulence promoters under selected operating conditions using a statistically designed test matrix; and Data reduction and analysis; The objective of Phase 3 research was to demonstrate the effectiveness of SpinTek's centrifugal membrane filtration as a pretreatment to remove suspended solids from a liquid waste upstream of 3M's WWL cartridge technology for the selective removal of technetium (Tc)

  1. Centrifugal pumps and allied machinery

    CERN Document Server

    Anderson, HH

    1994-01-01

    This book will be of vital interest to all engineers and designers concerned with centrifugal pumps and turbines. Including statistical information derived from 20000 pumps and 700 turbines with capacities of 5gpm to 5000000gpm, this book offers the widest range and scope of information currently available. Statistical analyses suggest practical methods of increasing pump performance and provide valuable data for new design aspects.

  2. Oscillatory Counter-Centrifugation: Effects of History and Lift Forces

    Science.gov (United States)

    Nadim, Ali

    2014-11-01

    This work is co-authored with my doctoral student Shujing Xu and is dedicated to the memory of my doctoral advisor Howard Brenner who enjoyed thought experiments related to rotating systems. Oscillatory Counter-Centrifugation refers to our theoretical discovery that within a liquid-filled container that rotates in an oscillatory manner about a fixed axis as a rigid body, a suspended particle can be made to migrate on average in the direction opposite to that of ordinary centrifugation. That is, a heavy (or light) particle can move toward (or away from) the rotation axis, when the frequency of oscillations is high enough. In this work we analyze the effects of the Basset history force and the Saffman lift force on particle trajectories and find that the counter-centrifugation phenomenon persists even when these forces are active.

  3. Secondary Containment Design for a High Speed Centrifuge

    Energy Technology Data Exchange (ETDEWEB)

    Snyder, K.W.

    1999-03-01

    Secondary containment for high speed rotating machinery, such as a centrifuge, is extremely important for operating personnel safety. Containment techniques can be very costly, ungainly and time consuming to construct. A novel containment concept is introduced which is fabricated out of modular sections of polycarbonate glazed into a Unistrut metal frame. A containment study for a high speed centrifuge is performed which includes the development of parameters for secondary containment design. The Unistrut/polycarbonate shield framing concept is presented including design details and proof testing procedures. The economical fabrication and modularity of the design indicates a usefulness for this shielding system in a wide variety of containment scenarios.

  4. Apparatus and method for centrifugation and robotic manipulation of samples

    Science.gov (United States)

    Vellinger, John C. (Inventor); Ormsby, Rachel A. (Inventor); Kennedy, David J. (Inventor); Thomas, Nathan A. (Inventor); Shulthise, Leo A. (Inventor); Kurk, Michael A. (Inventor); Metz, George W. (Inventor)

    2007-01-01

    A device for centrifugation and robotic manipulation of specimen samples, including incubating eggs, and uses thereof are provided. The device may advantageously be used for the incubation of avian, reptilian or any type of vertebrate eggs. The apparatus comprises a mechanism for holding samples individually, rotating them individually, rotating them on a centrifuge collectively, injecting them individually with a fixative or other chemical reagent, and maintaining them at controlled temperature, relative humidity and atmospheric composition. The device is applicable to experiments involving entities other than eggs, such as invertebrate specimens, plants, microorganisms and molecular systems.

  5. [Hemodynamic analysis of a centrifugal blood pump].

    Science.gov (United States)

    Wang, Yang; Yang, Ming; Xu, Zihao; Zhuang, Xiaoqi; Li, Qilei; Xu, Liang

    2015-01-01

    This paper built the mathematical model of a centrifugal blood pump, which was designed by ourselves, combined it with that of the human cardiovascular system and simulated the coupling system using Matlab. Then we set up the experiment platform, linked the blood pump to mock human cardiovascular system in case of three-stage heart failure, and measured aortic pressure and flow under different speed. The comparison between experiment results and simulation results not only indicates the coupling model is correct and the blood pump works well, but also shows that with the increase of blood pump speed, the pulsation of aortic pressure and flow will be reduced, this situation will affect the structure and function of blood vessels.

  6. [Hemodynamic analysis of a centrifugal blood pump].

    Science.gov (United States)

    Wang, Yang; Yang, Ming; Xu, Zihao; Zhuang, Xiaoqi; Li, Qilei; Xu, Liang

    2015-01-01

    This paper built the mathematical model of a centrifugal blood pump, which was designed by ourselves, combined it with that of the human cardiovascular system and simulated the coupling system using Matlab. Then we set up the experiment platform, linked the blood pump to mock human cardiovascular system in case of three-stage heart failure, and measured aortic pressure and flow under different speed. The comparison between experiment results and simulation results not only indicates the coupling model is correct and the blood pump works well, but also shows that with the increase of blood pump speed, the pulsation of aortic pressure and flow will be reduced, this situation will affect the structure and function of blood vessels. PMID:26027287

  7. Centrifugally driven microfluidic disc for detection of chromosomal translocations

    DEFF Research Database (Denmark)

    Brøgger, Anna Line; Kwasny, Dorota; Bosco, Filippo G.;

    2012-01-01

    and prognosis of patients. In this work we demonstrate a novel, centrifugally-driven microfluidic system for controlled manipulation of oligonucleotides and subsequent detection of chromosomal translocations. The device is fabricated in the form of a disc with capillary burst microvalves employed to control...

  8. Empirical Design Considerations for Industrial Centrifugal Compressors

    Directory of Open Access Journals (Sweden)

    Cheng Xu

    2012-01-01

    Full Text Available Computational Fluid Dynamics (CFD has been extensively used in centrifugal compressor design. CFD provides further optimisation opportunities for the compressor design rather than designing the centrifugal compressor. The experience-based design process still plays an important role for new compressor developments. The wide variety of design subjects represents a very complex design world for centrifugal compressor designers. Therefore, some basic information for centrifugal design is still very important. The impeller is the key part of the centrifugal stage. Designing a highly efficiency impeller with a wide operation range can ensure overall stage design success. This paper provides some empirical information for designing industrial centrifugal compressors with a focus on the impeller. A ported shroud compressor basic design guideline is also discussed for improving the compressor range.

  9. Test Results of a 1.2 kg/s Centrifugal Liquid Helium Pump for the ATLAS Superconducting Toroid Magnet System

    CERN Document Server

    Pengo, R; Passardi, Giorgio; Pirotte, O; ten Kate, H H J

    2002-01-01

    The toroid superconducting magnet of ATLAS-LHC experiment at CERN will be indirectly cooled by means of forced flow of liquid helium at about 4.5 K. A centrifugal pump will be used, providing a mass flow of 1.2 kg/s and a differential pressure of 40 kPa (ca. 400 mbar) at about 4300 rpm. Two pumps are foreseen, one for redundancy, in order to feed in parallel the cooling circuits of the Barrel and the two End-Caps toroid magnets. The paper describes the tests carried out at CERN to measure the characteristic curves, i.e. the head versus the mass flow at different rotational speeds, as well as the pump total efficiency. The pump is of the "fullemission" type, i.e. with curved blades and it is equipped with an exchangeable inducer. A dedicated pump test facility has been constructed at CERN, which includes a Coriolis-type liquid helium mass flow meter. This facility is connected to the helium refrigerator used for the tests at CERN of the racetrack magnets of the Barrel and of the End-Cap toroids.

  10. Design of Highspeed Tool Holder with Hydraulic Expansion System Driven by Centrifugal Force%离心力驱动液压膨胀式高速刀柄设计

    Institute of Scientific and Technical Information of China (English)

    王军; 马灿; 韩亚丽; 张淳

    2015-01-01

    针对高速刀柄与主轴锥孔离心膨胀不匹配的问题,设计了一种新型高速刀柄。刀柄采用实心短锥、双面定位结构。刀柄上安装有离心力驱动液压弹性膨胀系统,用以补偿刀柄与主轴锥孔的离心膨胀差。阐述了新型高速刀柄的结构原理,对刀柄几何参数和配合过盈量进行了设计;利用 ANSYS 有限元软件分析了刀柄的极限转速及与主轴的径向连接刚度。研究结果表明,新型刀柄与同规格的 HSK高速刀柄相比,极限转速提高了约38%,且径向连接刚度也有所提高,适合用于高速加工。%Against the centrifugal expansion mismatch of highspeed tool holder and taper hole of the spindle,a new type of highspeed tool holder was designed.It had the structure of short solid tapershank and doublesided positioning.A hydraulic elastic expansion system driven by centrifugal force was installed on the tool holder so as to compensate difference of the centrifugal expansions.The structure principle of tool holder was introduced herein.The geometrical parameters and interference were designed.The limit rotate speed and connection stiffness were analyzed by use of ANSYS.The reG search results prove that the limit rotate speed of new type of tool holder is 38% higher than that of the same specification HSK tool holder,and the radial connection stiffness is also improved to some extents,so this new type of tool holder is suitable to high speed machining.

  11. Effect of Centrifugation on Sesame Paste Temperature

    Directory of Open Access Journals (Sweden)

    Ahmad Kouchakzadeh

    2012-01-01

    Full Text Available The sesame seeds were mechanically cold pressed at temperature below 45 then centrifuged. No chemicals were used. The temperature during centrifugation of sesame paste was recorded. Temperatures in less than one hour operation has elevated to 148, 273 and 315 in 1200, 1800 and 2400 G-force centrifugal acceleration, respectively. since the centrifugal accelerations during the process cut at 1200, 1800 and 2400 G-force at about 35, 20 and 10 minutes, respectively. The maximum allowable temperatures raised to about 100 . Linear and quadratics regression model were fitted to data.

  12. Cavitation Effects in Centrifugal Pumps- A Review

    Directory of Open Access Journals (Sweden)

    Maxime Binama

    2016-05-01

    Full Text Available Cavitation is one of the most challenging fluid flow abnormalities leading to detrimental effects on both the centrifugal pump flow behaviors and physical characteristics. Centrifugal pumps’ most low pressure zones are the first cavitation victims, where cavitation manifests itself in form of pitting on the pump internal solid walls, accompanied by noise and vibration, all leading to the pump hydraulic performance degradation. In the present article, a general description of centrifugal pump performance and related parameters is presented. Based on the literature survey, some light were shed on fundamental cavitation features; where different aspects relating to cavitation in centrifugal pumps were briefly discussed

  13. Virgin Coconut Oil Production by Centrifugation Method

    Directory of Open Access Journals (Sweden)

    Y.C.Wong

    2014-03-01

    Full Text Available The virgin coconut oil (VCO production by centrifugation method was studied. The production of VCO was studied by using various centrifugation speed, temperature and time intervals. The results showed that the yield of VCO was 13.53% at 12000rpm, at 120 minutes. The highest yield of VCO was 13.80% at centrifugation temperature of 40oC. The concentration of lauric acid present in the samples with variables of centrifugation temperatures, speed, and time intervals were 0.4543µg, 6.2367µg, and 6.4894µg respectively.

  14. CFD simulation of centrifugal cells washers.

    Science.gov (United States)

    Kellet, Beth E; Binbing, Han; Dandy, David S; Wickramasinghe, S Ranil

    2004-01-01

    The feasibility of using computational fluid dynamics to guide the design of better centrifuges for processing shed blood is explored here. The velocity field and the rate of protein removal from the shed blood have been studied. The results indicate that computational fluid dynamics could help screen preliminary centrifuge bowl designs thus reducing the number of initial experimental tests required when developing new centrifuge bowls. Though the focus of this work is on washing shed blood the methods developed here are applicable to the design of centrifuge bowls for other blood processing applications. PMID:15133962

  15. Multiphase flow modeling in centrifugal partition chromatography.

    Science.gov (United States)

    Adelmann, S; Schwienheer, C; Schembecker, G

    2011-09-01

    The separation efficiency in Centrifugal Partition Chromatography (CPC) depends on selection of a suitable biphasic solvent system (distribution ratio, selectivity factor, sample solubility) and is influenced by hydrodynamics in the chambers. Especially the stationary phase retention, the interfacial area for mass transfer and the flow pattern (backmixing) are important parameters. Their relationship with physical properties, operating parameters and chamber geometry is not completely understood and predictions are hardly possible. Experimental flow visualization is expensive and two-dimensional only. Therefore we simulated the flow pattern using a volume-of-fluid (VOF) method, which was implemented in OpenFOAM®. For the three-dimensional simulation of a rotating FCPC®-chamber, gravitational centrifugal and Coriolis forces were added to the conservation equation. For experimental validation the flow pattern of different solvent systems was visualized with an optical measurement system. The amount of mobile phase in a chamber was calculated from gray scale values of videos recorded by an image processing routine in ImageJ®. To visualize the flow of the stationary phase polyethylene particles were used to perform a qualitative particle image velocimetry (PIV) analysis. We found a good agreement between flow patterns and velocity profiles of experiments and simulations. By using the model we found that increasing the chamber depth leads to higher specific interfacial area. Additionally a circular flow in the stationary phase was identified that lowers the interfacial area because it pushes the jet of mobile phase to the chamber wall. The Coriolis force alone gives the impulse for this behavior. As a result the model is easier to handle than experiments and allows 3D prediction of hydrodynamics in the chamber. Additionally it can be used for optimizing geometry and operating parameters for given physical properties of solvent systems. PMID:21324465

  16. Centrifugal quantum states of neutrons

    Science.gov (United States)

    Nesvizhevsky, V. V.; Petukhov, A. K.; Protasov, K. V.; Voronin, A. Yu.

    2008-09-01

    We propose a method for observation of the quasistationary states of neutrons localized near a curved mirror surface. The bounding effective well is formed by the centrifugal potential and the mirror Fermi potential. This phenomenon is an example of an exactly solvable “quantum bouncer” problem that can be studied experimentally. It could provide a promising tool for studying fundamental neutron-matter interactions, as well as quantum neutron optics and surface physics effects. We develop a formalism that describes quantitatively the neutron motion near the mirror surface. The effects of mirror roughness are taken into account.

  17. MR Continuously Variable Transmission Driven by SMA for Centrifugal Fan in Nuclear Power Plant

    OpenAIRE

    Jianzuo Ma; Hongyu Shu; Jin Huang

    2012-01-01

    The running efficiency of centrifugal fan affects the economical efficiency of the ventilation system. In this paper, we proposed a continuously variable transmission system based on magnetorheological fluid and shape memory alloy for improving the operating efficiency of the centrifugal fan. The equation of transmission torque developed by magnetorheological fluid is derived to compute the torque transmission ability in the continuously variable transmission system. A shape memory alloy spri...

  18. Potential commercial applications of centrifuge technology

    International Nuclear Information System (INIS)

    As part of an effort to prevent the loss of and maximize the use of unique developments of the centrifuge program, this document identifies and briefly describes unclassified technologies potentially available for transfer. In addition, this document presents a preliminary plan for action needed to carry out the transfer activity. Continuing efforts will provide additional descriptions of technologies which have applications that are not as apparent or as obvious as those presented here. Declassification of some of the program information, now classified as restricted data, would permit the descriptions of additional technologies which have significant commercial potential. The following are major areas of technology where transfer opportunities exist: biomedical; separation; motors and control systems; materials; vacuum; dynamics and balancing; and diagnostics and instrumentation

  19. Centrifuge modelling of offshore monopile foundation

    DEFF Research Database (Denmark)

    Klinkvort, Rasmus Tofte; Hededal, Ole

    2010-01-01

    centrifuge tests on a laterally loaded monopile in dry sand. The prototype dimension of the piles was modelled to a diameter of 1 meter and penetration depth on 6 meter. The test series were designed in order to investigate the scaling laws in the centrifuge both for monotonic and cyclic loading...

  20. Detection methods for centrifugal microfluidic platforms

    DEFF Research Database (Denmark)

    Burger, Robert; Amato, Letizia; Boisen, Anja

    2016-01-01

    Centrifugal microfluidics has attracted much interest from academia as well as industry, since it potentially offers solutions for affordable, user-friendly and portable biosensing. A wide range of so-called fluidic unit operations, e.g. mixing, metering, liquid routing, and particle separation...... for the centrifugal microfluidics platform and cover optical as well as mechanical and electrical detection principles....

  1. High frequency dynamics in centrifugal compressors

    NARCIS (Netherlands)

    Twerda, A.; Meulendijks, D.; Smeulers, J.P.M.; Handel, R. van den; Lier, L.J. van

    2008-01-01

    Problems with centrifugal compressors relating to high frequency, i.e. Blade passing frequency (BPF) are increasing. Pulsations and vibrations generated in centrifugal compressors can lead to nuisance, due to strong tonal noise, and even breakdown. In several cases the root cause of a failure or a n

  2. Rotor for a pyrolysis centrifuge reactor

    DEFF Research Database (Denmark)

    2015-01-01

    The present invention relates to a rotor for a pyrolysis centrifuge reactor, said rotor comprising a rotor body having a longitudinal centre axis, and at least one pivotally mounted blade being adapted to pivot around a pivot axis under rotation of the rotor body around the longitudinal centre axis....... Moreover, the present invention relates to a pyrolysis centrifuge reactor applying such a rotor....

  3. Blade Crack Detection of Centrifugal Fan Using Adaptive Stochastic Resonance

    Directory of Open Access Journals (Sweden)

    Bingbing Hu

    2015-01-01

    Full Text Available Centrifugal fans are widely used in various industries as a kind of turbo machinery. Among the components of the centrifugal fan, the impeller is a key part because it is used to transform kinetic energy into pressure energy. Crack in impeller’s blades is one of the serious hidden dangers. It is important to detect the cracks in the blades as early as possible. Based on blade vibration signals, this research applies an adaptive stochastic resonance (ASR method to diagnose crack fault in centrifugal fan. The ASR method, which can utilize the optimization ability of the grid search method and adaptively realize the optimal stochastic resonance system matching input signals, may weaken the noise and highlight weak characteristic and thus can diagnose the fault accurately. A centrifugal fan test rig is established and experiments with three cases of blades are conducted. In comparison with the ensemble empirical mode decomposition (EEMD analysis and the traditional Fourier transform method, the experiment verified the effectiveness of the current method in blade crack detection.

  4. Cyber meets nuclear - Stuxnet and the cyberattacks on Iranian centrifuges

    International Nuclear Information System (INIS)

    In 2010 the computer worm Stuxnet attacked the information hardware of the Iranian uranium enrichment program. Stuxnet spread by USB flash drives and attacked SCADA software installed on Windows systems via several zero-day exploits. SCADA configures programmable logic controllers which control in the case of the Iranian centrifuge cascades frequency converter drives to choose the frequency of centrifuge motors. Thus the attackers were able to either change the rotation frequency of the rotor and thereby the separative power of the centrifuge or even destroy the fast spinning centrifuges by stopping and restarting them. The designers of Stuxnet must have had intimate knowledge of the facility design as e.g. the cascade connection scheme was programmed into Stuxnet. Based on this information some calculations of the Iranian cascade regarding the potential to produce highly enriched uranium will be presented using cascade simulation tools. The use of such highly sophisticated computer attacks to sabotage a nuclear program shed a new light on the debate about cyber attacks and the use of information technology for kinetic attacks in general. The talk will address problems the weaponization of information technology poses for international security and will highlight some more recent developments.

  5. Fault Diagnosis in a Centrifugal Pump Using Active Magnetic Bearings

    OpenAIRE

    Nordmann Rainer; Aenis Martin

    2004-01-01

    The number of rotors running in active magnetic bearings (AMBs) has increased over the last few years. These systems offer a great variety of advantages compared to conventional systems. The aim of this article is to use the AMBs together with a developed built-in software for identification, fault detection, and diagnosis in a centrifugal pump. A single-stage pump representing the turbomachines is investigated. During full operation of the pump, the AMBs are used as actuators to generate def...

  6. Design of centrifugal impeller blades

    Science.gov (United States)

    Betz, A; Flugge-Lotz, I

    1939-01-01

    This paper restricts itself to radial impellers with cylindrical blades since, as Prasil has shown, the flow about an arbitrarily curved surface of revolution may be reduced to this normal form we have chosen by a relatively simple conformal transformation. This method starts from the simple hypotheses of the older centrifugal impeller theory by first assuming an impeller with an infinite number of blades. How the flow is then modified is then investigated. For the computation of flow for a finite number of blades, the approximation method as developed by Munk, Prandtl and Birnbaum, or Glauert is found suitable. The essential idea of this method is to replace the wing by a vortex sheet and compute the flow as the field of these vortices. The shape of the blades is then obtained from the condition that the flow must be along the surface of the blade.

  7. Modelling of horizontal centrifugal casting of work roll

    Science.gov (United States)

    Xu, Zhian; Song, Nannan; Tol, Rob Val; Luan, Yikun; Li, Dianzhong

    2012-07-01

    A numerical model to simulate horizontal centrifugal roll castings is presented in this paper. In order to simulate the flow fluid and solidification of horizontal centrifugal roll casting correctly, the model uses a body fitted mesh technique to represent the geometry. This new method maps a plate layer mesh to a circular mesh. The smooth body fitted mesh method gives more accurate calculation results for cylindrical geometries. A velocity depending on the angular velocity and inner radius of the mould is set up as a velocity boundary condition. The fluid flow coupled with heat transfer and solidification in a rapidly rotating roll is simulated. A gravity free falling method is applied as a pouring condition. A moveable pouring system is also used in the simulations. High speed steel is used to produce the work roll. Two different gating positions and a moveable gating system are simulated in this paper. Results show that the position of pouring system has a significant influence on the temperature distribution. The temperature distribution at a fixed central pouring system is more favourable than the distribution from a side pouring system. A moving gating system method is a better way to obtain a uniform temperature field in centrifugal casting and offers an alternative for existing techniques.

  8. Centrifuge workers study. Phase II, completion report

    Energy Technology Data Exchange (ETDEWEB)

    Wooten, H.D.

    1994-09-01

    Phase II of the Centrifuge Workers Study was a follow-up to the Phase I efforts. The Phase I results had indicated a higher risk than expected among centrifuge workers for developing bladder cancer when compared with the risk in the general population for developing this same type of cancer. However, no specific agent could be identified as the causative agent for these bladder cancers. As the Phase II Report states, Phase I had been limited to workers who had the greatest potential for exposure to substances used in the centrifuge process. Phase II was designed to expand the survey to evaluate the health of all employees who had ever worked in Centrifuge Program Departments 1330-1339 but who had not been interviewed in Phase I. Employees in analytical laboratories and maintenance departments who provided support services for the Centrifuge Program were also included in Phase II. In December 1989, the Oak Ridge Associated Universities (ORAU), now known as Oak Ridge Institute for Science and Education (ORISE), was contracted to conduct a follow-up study (Phase II). Phase H of the Centrifuge Workers Study expanded the survey to include all former centrifuge workers who were not included in Phase I. ORISE was chosen because they had performed the Phase I tasks and summarized the corresponding survey data therefrom.

  9. Centrifuge workers study. Phase II, completion report

    International Nuclear Information System (INIS)

    Phase II of the Centrifuge Workers Study was a follow-up to the Phase I efforts. The Phase I results had indicated a higher risk than expected among centrifuge workers for developing bladder cancer when compared with the risk in the general population for developing this same type of cancer. However, no specific agent could be identified as the causative agent for these bladder cancers. As the Phase II Report states, Phase I had been limited to workers who had the greatest potential for exposure to substances used in the centrifuge process. Phase II was designed to expand the survey to evaluate the health of all employees who had ever worked in Centrifuge Program Departments 1330-1339 but who had not been interviewed in Phase I. Employees in analytical laboratories and maintenance departments who provided support services for the Centrifuge Program were also included in Phase II. In December 1989, the Oak Ridge Associated Universities (ORAU), now known as Oak Ridge Institute for Science and Education (ORISE), was contracted to conduct a follow-up study (Phase II). Phase H of the Centrifuge Workers Study expanded the survey to include all former centrifuge workers who were not included in Phase I. ORISE was chosen because they had performed the Phase I tasks and summarized the corresponding survey data therefrom

  10. Isolation of exosomes by differential centrifugation: Theoretical analysis of a commonly used protocol

    Science.gov (United States)

    Livshts, Mikhail A.; Khomyakova, Elena; Evtushenko, Evgeniy G.; Lazarev, Vassili N.; Kulemin, Nikolay A.; Semina, Svetlana E.; Generozov, Edward V.; Govorun, Vadim M.

    2015-11-01

    Exosomes, small (40-100 nm) extracellular membranous vesicles, attract enormous research interest because they are carriers of disease markers and a prospective delivery system for therapeutic agents. Differential centrifugation, the prevalent method of exosome isolation, frequently produces dissimilar and improper results because of the faulty practice of using a common centrifugation protocol with different rotors. Moreover, as recommended by suppliers, adjusting the centrifugation duration according to rotor K-factors does not work for “fixed-angle” rotors. For both types of rotors - “swinging bucket” and “fixed-angle” - we express the theoretically expected proportion of pelleted vesicles of a given size and the “cut-off” size of completely sedimented vesicles as dependent on the centrifugation force and duration and the sedimentation path-lengths. The proper centrifugation conditions can be selected using relatively simple theoretical estimates of the “cut-off” sizes of vesicles. Experimental verification on exosomes isolated from HT29 cell culture supernatant confirmed the main theoretical statements. Measured by the nanoparticle tracking analysis (NTA) technique, the concentration and size distribution of the vesicles after centrifugation agree with those theoretically expected. To simplify this “cut-off”-size-based adjustment of centrifugation protocol for any rotor, we developed a web-calculator.

  11. In vitro pulsatility analysis of axial-flow and centrifugal-flow left ventricular assist devices.

    Science.gov (United States)

    Stanfield, J Ryan; Selzman, Craig H

    2013-03-01

    Recently, continuous-flow ventricular assist devices (CF-VADs) have supplanted older, pulsatile-flow pumps, for treating patients with advanced heart failure. Despite the excellent results of the newer generation devices, the effects of long-term loss of pulsatility remain unknown. The aim of this study is to compare the ability of both axial and centrifugal continuous-flow pumps to intrinsically modify pulsatility when placed under physiologically diverse conditions. Four VADs, two axial- and two centrifugal-flow, were evaluated on a mock circulatory flow system. Each VAD was operated at a constant impeller speed over three hypothetical cardiac conditions: normo-tensive, hypertensive, and hypotensive. Pulsatility index (PI) was compared for each device under each condition. Centrifugal-flow devices had a higher PI than that of axial-flow pumps. Under normo-tension, flow PI was 0.98 ± 0.03 and 1.50 ± 0.02 for the axial and centrifugal groups, respectively (p centrifugal pumps, respectively (p = 0.01). Under hypotension, PI was 0.73 ± 0.02 and 0.78 ± 0.02 for the axial and centrifugal groups, respectively (p = 0.13). All tested CF-VADs were capable of maintaining some pulsatile-flow when connected in parallel with our mock ventricle. We conclude that centrifugal-flow devices outperform the axial pumps from the basis of PI under tested conditions.

  12. Gas dynamics in strong centrifugal fields

    Energy Technology Data Exchange (ETDEWEB)

    Bogovalov, S.V.; Kislov, V.A.; Tronin, I.V. [National research nuclear university “MEPhI”, Kashirskoje shosse, 31,115409, Moscow (Russian Federation)

    2015-03-10

    Dynamics of waves generated by scopes in gas centrifuges (GC) for isotope separation is considered. The centrifugal acceleration in the GC reaches values of the order of 106g. The centrifugal and Coriolis forces modify essentially the conventional sound waves. Three families of the waves with different polarisation and dispersion exist in these conditions. Dynamics of the flow in the model GC Iguasu is investigated numerically. Comparison of the results of the numerical modelling of the wave dynamics with the analytical predictions is performed. New phenomena of the resonances in the GC is found. The resonances occur for the waves polarized along the rotational axis having the smallest dumping due to the viscosity.

  13. Concept for a short arm human centrifuge onbord ISS.

    Science.gov (United States)

    Kuebler, Ulrich; Grinberg, Anna; Kern, Peter

    Astrium is presently performing for ESA a definition study about the accommodation of a short arm human centrfiuge into a spacecraft. A scientific workshop has been part of the study with the goal to define from various research fields (e.g. cardiovascular, gravitational biology, neuroscience, bone/muscle) requirements for such an artificial gravity system on ISS. As a second step the requirements were consolidated to a set of common specfications for the developemnt of a centrifuge system serving as integrated countermeasure for longterm exposure to g. The presentation will focus on the scientific requirements and the respective translation into technical requirement, finally leading to a centrifuge concept, including accommodation possi-bilities onbord ISS.

  14. Modeling of Centrifugal Force Field and the Effect on Filling and Solidification in Centrifugal Casting

    Science.gov (United States)

    Sheng, Wenbin; Ma, Chunxue; Gu, Wanli

    2011-06-01

    Based on the steady flow in a tube, a mathematical model has been established for the consideration of centrifuging force field by combining the equations of continuity, conservation of momentum and general energy. Effects of centrifugal field on the filling and solidification are modeled by two accessional terms: centrifugal force and Chorios force. In addition, the transfer of heat by convection is considered to achieve a coupling calculation of velocity field and temperature field. The solution of pressure item is avoided by introducing the stream function ψ(x,y) and the eddy function ξ(x,y). Corresponding difference formats for the simultaneous equations of centrifugal filling, the accessional terms and the solidifying latent heat have been established by the finite difference technique. Furthermore, the centrifugal filling and solidification processes in a horizontal tube are summarized to interpret the mechanism by which internal defects are formed in centrifugal castings.

  15. Dynamic Actuator for Centrifuge Modeling of Soil-Structure Interaction

    OpenAIRE

    CABRERA, Miguel Angel; Caicedo, Bernardo; THOREL, Luc

    2012-01-01

    This paper presents a new dynamic actuator useful to study soil-structure interactions in a centrifuge. This new dynamic apparatus is based on an amplified piezoelectric actuator. Using this device it is possible to create vibrations in the soil sample of different frequencies and amplitudes. The dynamic actuator consists of a set of weights in a single degree of freedom system plus a piezoelectric actuator and a piezoelectric load cell, which measures the dynamic load. A description of the d...

  16. Centrifugal compressor flow instabilities at lowmass flow rate

    OpenAIRE

    Sundström, Elias

    2016-01-01

    Turbochargers play an important role in increasing the energetic efficiency andreducing emissions of modern power-train systems based on downsized recipro-cating internal combustion engines (ICE). The centrifugal compressor in tur-bochargers is limited at off-design operating conditions by the inception of flowinstabilities causing rotating stall and surge. They occur at reduced enginespeeds (low mass flow rates), i.e. typical operating conditions for a betterengine fuel economy, harming ICEs...

  17. Molecular structure and centrifugal distortion in methylthioethyne

    NARCIS (Netherlands)

    Engelsen, D. den

    1969-01-01

    The investigation of the microwave spectra of five isotopic species of methylthioethyne, HCCSCH3 enabled a fairly reliable calculation to be made of bond lengths and angles. The centrifugal distortion parameters are related to molecular vibrations.

  18. Determination of Possible Wear on the Centrifugal Pump Wheel Used for Agricultural Irrigation Purposes

    OpenAIRE

    Yuksel, E; B. Eker

    2009-01-01

    The extent of this work is operating characteristics of a horizontal shafted centrifugal pump which has been operated for 6 ½ to 7 hours on the average. A closed circuit pump system (circulating within itself) which was formed by attaching a horizontal shafted centrifugal pump which can be used in irrigation applications with a drum has been operated for 180 hours at laboratory conditions. To define the operating properties of the pump, its operating characteristics were measured in respect t...

  19. Towards Centrifugal Compressor Stages Virtual Testing

    OpenAIRE

    Guidotti, Emanuele

    2014-01-01

    Flow features inside centrifugal compressor stages are very complicated to simulate with numerical tools due to the highly complex geometry and varying gas conditions all across the machine. For this reason, a big effort is currently being made to increase the fidelity of the numerical models during the design and validation phases. Computational Fluid Dynamics (CFD) plays an increasing role in the assessment of the performance prediction of centrifugal compressor stages. Historically, CFD wa...

  20. Meridional Considerations of the Centrifugal Compressor Development

    OpenAIRE

    Xu, C.; Amano, R. S.

    2012-01-01

    Centrifugal compressor developments are interested in using optimization procedures that enable compressor high efficiency and wide operating ranges. Recently, high pressure ratio and efficiency of the centrifugal compressors require impeller design to pay attention to both the blade angle distribution and the meridional profile. The geometry of the blades and the meridional profile are very important contributions of compressor performance and structure reliability. This paper presents some ...

  1. CFD Simulation of Annular Centrifugal Extractors

    OpenAIRE

    Vedantam, S.; Wardle, K. E.; Tamhane, T. V.; Ranade, V. V.; Joshi, J. B.

    2012-01-01

    Annular centrifugal extractors (ACE), also called annular centrifugal contactors offer several advantages over the other conventional process equipment such as low hold-up, high process throughput, low residence time, low solvent inventory and high turn down ratio. The equipment provides a very high value of mass transfer coefficient and interfacial area in the annular zone because of the high level of power consumption per unit volume and separation inside the rotor due to the high g of cent...

  2. Finite element analysis of centrifugal impellers

    OpenAIRE

    Sham Sunder, K.

    1981-01-01

    A three-dimensional method of stress analysis using finite element techniques is presented for determining the stress distribution in centrifugal impellers. It can treat all of the three types of loading possible in an inpeller, viz centrifugal, thermal and fluid. The method has no known limitations with regards to the geometric factors such as asymnetry of disk, blade curvature, presence of a cover disk or shroud, single or double sided impeller etc. A comparison of r...

  3. CFD Analysis of Centrifugal Pump: A Review

    OpenAIRE

    Narayan P. Jaiswal

    2014-01-01

    The main objective of this work is to understand role of the computational fluid dynamics (CFD) technique in analyzing and predicting the performance of centrifugal pump. Computational Fluid Dynamics (CFD) is the present day state-of-art technique for fluid flow analysis. The critical review of CFD analysis of CFD analysis of centrifugal pump along with future scope for further improvement is presented in this paper. Different solver like ANSYS-CFX, FLUENT etc can be used for ...

  4. Return Vane Installed in Multistage Centrifugal Pump

    OpenAIRE

    Miyano, Masafumi; Kanemoto, Toshiaki; Kawashima, Daisuke; Wada, Akihiro; Hara, Takashi; Sakoda, Kazuyuki

    2008-01-01

    To optimize the stationary components in the multistage centrifugal pump, the effects of the return vane profile on the performances of the multistage centrifugal pump were investigated experimentally, taking account of the inlet flow conditions for the next stage impeller. The return vane, whose trailing edge is set at the outer wall position of the annular channel downstream of the vane and which discharges the swirl-less flow, gives better pump performances. By equipping such return vane w...

  5. Enrichment technology. Dependable vendor of gas centrifuges

    International Nuclear Information System (INIS)

    Enrichment Technology is an innovative, high-tech company that develops, manufactures and installs gas centrifuges for enriching uranium. In addition, Enrichment Technology designs enrichment plants that use gas centrifuge technology. This technology offers the most efficient and cost-effective method for enriching uranium yet: high-performance, safe technology that dominates the market with a global share of 45 percent. A determining factor in Enrichment Technology's success is its mission: supplying its customers with safe, reliable technology. Production of the centrifuges requires versatile know-how and collaboration between different departments as well as interdisciplinary teams at the various sites. More than 2000 operators at 8 sites in 5 countries contribute their individual knowledge and personal skills in order to produce this exceptional technology. The head office is in Beaconsfield near London and the operational headquarters are in Almelo in the Netherlands. There are other sites in Germany (Juelich und Gronau), Great Britain (Capenhurst) as well as project sites in the USA and France. Capenhurst is where experienced engineers design new enrichment plants and organise their construction. Centrifuge components are manufactured in Almelo and Juelich, while the pipework needed to connect up the centrifuges is produced at the site in Gronau. In Juelich, highly qualified scientists in interdisciplinary teams are continuously researching ways of improving the current centrifuges. Communication between specialists in the fields of chemistry, physics and engineering forms the basis for the company's success and the key to extending this leading position in the global enrichment market. (orig.)

  6. Clinical experience with the Sarns centrifugal pump.

    Science.gov (United States)

    Curtis, J J; Walls, J T; Demmy, T L; Boley, T M; Schmaltz, R A; Goss, C F; Wagner-Mann, C C

    1993-07-01

    Since October 1986, we have had experience with 96 Sarns centrifugal pumps in 72 patients (pts). Heparinless left atrial to femoral artery or aorta bypass was used in 14 pts undergoing surgery on the thoracic aorta with 13 survivors (93%). No paraplegia or device-related complications were observed. In 57 patients, the Sarns centrifugal pump was used as a univentricular (27 pts) or biventricular (30 pts) cardiac assist device for postcardiotomy cardiogenic shock. In these patients, cardiac assist duration ranged from 2 to 434 h with a hospital survival rate of 29% in those requiring left ventricular assist and 13% in those requiring biventricular assist. Although complications were ubiquitous in this mortally ill patient population, in 5,235 pump-hours, no pump thrombosis was observed. Hospital survivors followed for 4 months to 6 years have enjoyed an improved functional class. We conclude that the Sarns centrifugal pump is an effective cardiac assist device when used to salvage patients otherwise unweanable from cardiopulmonary bypass. Partial left ventricular bypass using a centrifugal pump has become our procedure of choice for unloading the left ventricle and for maintenance of distal aortic perfusion pressure when performing surgery on the thoracic aorta. This clinical experience with the Sarns centrifugal pump appears to be similar to that reported with other centrifugal assist devices.

  7. Considerations in designing a centrifugal atomiser for metal powder production

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Y.Y. [Department of Engineering, The University of Liverpool, Liverpool L69 3GH (United Kingdom)]. E-mail: y.y.zhao@livepool.ac.uk

    2006-07-01

    In centrifugal atomisation for metal powder production, the key to the control of the particle sizes is the design of the atomiser. This paper studies the main issues concerned in designing a centrifugal atomiser and provides guidance on the selection of an electric motor, radius of atomiser, slope angle of atomiser wall and flow rate of cooling water. In the selection of the atomiser radius, the power and material constraints as well as the hydraulic jump radius need to be considered. A cup atomiser with a slope angle of 60-70{sup o} would result in small spray droplets and thus a fine powder. The water cooling system needs to be assessed by examining the heat flow in the solid metal layer and in the atomiser.

  8. Stage-efficiency of centrifugal extractor used in nuclear industry

    Institute of Scientific and Technical Information of China (English)

    吴秋林; 景山; 王兴海; 宋崇立

    2003-01-01

    The stage-efficiency of a single-stage prototype (d70) centrifugal extractor and the cascade is tested by HNO3-Nd3+ and 30%TRPO-kerosene system. The experimental results of the single-stage centrifugal extractor show that the carryover of the two phases decreases with increasing ratio of the two flow rate and rotation rate and the stage efficiency increases with not only decreasing total flow rate but also increasing rotor speed. However, the experimental results of the cascade show that the average stage efficiency of the cascade increases with not only decreasing total flow rate but also increasing rotor speed in both three-stage mode and two-stage mode.

  9. Numerical investigation of suction vortices behavior in centrifugal pump

    Energy Technology Data Exchange (ETDEWEB)

    An, Young Joon; Shin, Byeong Rog [Changwon National University, Changwon (Korea, Republic of)

    2011-03-15

    A numerical simulation on suction vortices behavior in a centrifugal pump was carried out to investigate their influence on the internal flow through impellers including formation and shedding of cavitation by using a finite-volume method and k-{omega} Shear Stress Transport turbulence model. For cavitating flow, a two phase homogeneous cavitation model was used. A full three-dimensional flow in a single section centrifugal pump consisting of a six blade impeller and shroud ring was computed with structured mesh. A constant suction vortex is imposed as a boundary condition. Vortices behavior was investigated according to the variation of flow rates of two pump systems with and without suction vortices. From the results, suction vortices induced biased flow structure and more cavitations, especially at the low flow rate condition. Complicated internal flow phenomena through impellers such as formation of cavitations, growing and shedding of the vortex, flow separation and flow unsteadiness due to the suction vortices are investigated and discussed.

  10. Numerical investigation of suction vortices behavior in centrifugal pump

    International Nuclear Information System (INIS)

    A numerical simulation on suction vortices behavior in a centrifugal pump was carried out to investigate their influence on the internal flow through impellers including formation and shedding of cavitation by using a finite-volume method and k-ω Shear Stress Transport turbulence model. For cavitating flow, a two phase homogeneous cavitation model was used. A full three-dimensional flow in a single section centrifugal pump consisting of a six blade impeller and shroud ring was computed with structured mesh. A constant suction vortex is imposed as a boundary condition. Vortices behavior was investigated according to the variation of flow rates of two pump systems with and without suction vortices. From the results, suction vortices induced biased flow structure and more cavitations, especially at the low flow rate condition. Complicated internal flow phenomena through impellers such as formation of cavitations, growing and shedding of the vortex, flow separation and flow unsteadiness due to the suction vortices are investigated and discussed

  11. Waste minimization and resource recovery using centrifugation and thermal desorption

    International Nuclear Information System (INIS)

    Separation and Recovery Systems, Inc. (SRS) provides on-site waste minimization and resource recovery using its state-of-the-art MX-1500 centrifuge and MX-2000 thermal desorber. The MX-1500 can process over 450 feed tons of material per day, resulting in centrifuged cake containing 20% to 60% by weight. The MX-2000 is a hollow-flite thermal processor indirectly heated by either steam or hot oil. SRS has dewatered and/or deoiled over 1,000,000 feed tons of material in the refining, chemical, and energy industries using the MX-1500. SRS estimates that over 300,000 barrels of reusable oil have been recovered from that material. Additionally, SRS has dried and/or detoxified over 150,000 wet tons of solids or soil to regulatory or customer-specified limits using the MX-2000

  12. Centrifuge Modeling of Piles Subjected to Lateral Loads

    Science.gov (United States)

    Brant, Logan; Ling, Hoe I.

    There are many applications where piles are employed to absorb and deflect lateral impact loads. Structural elements of this type are used to protect infrastructure and are commonly found at marine sites. A series of model tests have been conducted using Columbia University's centrifuge facility to better understand the performance of piles subjected to these loading conditions. A device was designed to install and laterally load single model piles during centrifuge flight. This device uniquely contains two lateral loading systems, one which allows static testing and another appropriate for dynamic tests. This research examines the behavior of tubular steel piles embedded within dry or saturated soil and subjected to varied rates of lateral loading. This investigation provides insight on the contribution of lateral loading rates to the behavior of piles.

  13. Study of the applicability of non-conventional aqueous two-phase systems in counter-current and centrifugal partition chromatography.

    Science.gov (United States)

    Bezold, Franziska; Goll, Johannes; Minceva, Mirjana

    2015-04-01

    Aqueous two-phase systems composed of imidazolium-based ionic liquids and phosphate salts were evaluated for their applicability in liquid-liquid chromatography. The influence of the nature of ionic liquid anion and cation on the partitioning of bovine serum albumin, lysozyme and myoglobin was investigated. A mixture of K2HPO4 and KH2PO4 in a ratio of 1.82:1 wt/wt was used in all of the tested biphasic systems to adjust the pH to a range of 7-8. The results show that more hydrophobic cations decrease the partition coefficients of the proteins in the biphasic systems and outweigh the effect of the anion on the distribution of the macromolecules. Viscosities and densities of the biphasic systems were in a suitable range for liquid-liquid chromatography. Even though the partition coefficients were too high for a conventional batch operation mode, these aqueous two-phase systems show favorable properties for protein capturing in liquid-liquid chromatographic columns. Additionally, the possible application of ionic liquids as modifiers in polyethylene glycol (PEG)-based aqueous two-phase systems was investigated. It could be demonstrated that ionic liquids alter the partition coefficients of the proteins. PMID:25736304

  14. Need, utilization, and configuration of a large, multi-G centrifuge on the Space Station

    Science.gov (United States)

    Bonting, Sjoerd L.

    1987-01-01

    A large, multi-g centrifuge is required on the Space Station (1) to provide valid 1-g controls for the study of zero-g effects on animals and plants and to study readaptation to 1 g; (2) to store animals at 1 g prior to short-term zero-g experimentation; (3) to permit g-level threshold studies of gravity effects. These requirements can be met by a 13-ft-diam., center-mounted centrifuge, on which up to 48 modular habitats with animals (squirrel monkey, rat, mouse) and plants are attached. The advantages of locating this centrifuge with the vivarium, a common environmental control and life support system, a general-purpose work station and storage of food, water, and supplies in an attached short module, are elaborated. Servicing and operation of the centrifuge, as well as minimizing its impact on other Space Station functions are also considered.

  15. Active pneumatic control of centrifugal microfluidic flows for lab-on-a-chip applications.

    Science.gov (United States)

    Clime, Liviu; Brassard, Daniel; Geissler, Matthias; Veres, Teodor

    2015-06-01

    This paper reports a novel method of controlling liquid motion on a centrifugal microfluidic platform based on the integration of a regulated pressure pump and a programmable electromechanical valving system. We demonstrate accurate control over the displacement of liquids within the system by pressurizing simultaneously multiple ports of the microfluidic device while the platform is rotating at high speed. Compared to classical centrifugal microfluidic platforms where liquids are solely driven by centrifugal and capillary forces, the method presented herein adds a new degree of freedom for fluidic manipulation, which represents a paradigm change in centrifugal microfluidics. We first demonstrate how various core microfluidic functions such as valving, switching, and reverse pumping (i.e., against the centrifugal field) can be easily achieved by programming the pressures applied at dedicated access ports of the microfluidic device. We then show, for the first time, that the combination of centrifugal force and active pneumatic pumping offers the possibility of mixing fluids rapidly (~0.1 s) and efficiently based on the creation of air bubbles at the bottom of a microfluidic reservoir. Finally, the suitability of the developed platform for performing complex bioanalytical assays in an automated fashion is demonstrated in a DNA harvesting experiment where recovery rates of about 70% were systematically achieved. The proposed concept offers the interesting prospect to decouple basic microfluidic functions from specific material properties, channel dimensions and fabrication tolerances, surface treatments, or on-chip active components, thus promoting integration of complex assays on simple and low-cost microfluidic cartridges.

  16. Numerical and experimental investigation of the centrifugal stage axial compressor centrifugal stationary GTE

    OpenAIRE

    Шаровский, Михаил Антонович; Усатенко, Елена Александровна; Шелковский, Михаил Юрьевич; Зубрицкая, Инна Аркадьевна

    2012-01-01

    About increase in efficiency of a centrifugal step of the compressor in low-dimensional GTD with the osetsentrobezhny compressor. Use of the “closed” driving wheel as basic possibility of receiving a highly effective centrifugal step. The gazodinamichesky aspect of its design and manufacturing is considered.

  17. 离心式压缩机转子系统稳定性控制方法研究%Instability control strategy for rotor-bearing system in centrifugal compressor

    Institute of Scientific and Technical Information of China (English)

    王维民; 齐鹏逸; 李启行; 高金吉

    2014-01-01

    For a centrifugal compressor,as its capacity,compression ratio and efficiency,instability of its inner rotor-bearing system becomes the major obstacle for its operation in a long period without shutdown.Based on the study on its mechanism and influencial factors,the control strategy for improving the stability of the rotor bearing system was discussed.By introducing a case study about a centrifugal compressor with several instable faults,the transient response was investigated to find the effect of rotating speed and cross coupling stiffness of seal on the stability of rotor.Then the force exerted on the rotor was controlled by using a controller through two ways,namely,the displacement feed-back and velocity feed-back strategy.With displacement feed-back,the controller functions as a spring with cross-coupling stiffness against the seal.While,it functions as a damper when velocity feed-back was adopted.The results indicate that both strategies can depress the vibration caused by the instability of the rotor.Furthermore,the displacement feed-back strategy has high efficiency because of its lower power consuming.The results can provide some new insight and feasibility for controlling or upgrading the stability of compressor rotor-bearing system.%针对离心压缩机转子失稳已成高效长周期运转主要障碍问题,通过分析失稳机理及影响因素,研究压缩机转子系统稳定性控制方法。结合工程案例,采用有限元方法对转子进行瞬态动力学分析,研究转速及因密封等部件交叉刚度对转子稳定性影响。研究转子振动位移反馈与速度反馈方法对转子失稳振动的控制效果。结果表明,两种方法均能有效提高转子系统稳定性。对比在达到相同控制效果时执行机构能量消耗表明,通过位移反馈方式能以更低能耗达到控制效果。该结果可为离心压缩机转子稳定性控制与提高提供新的思路及可行性。

  18. Concentration and purification of poliovirus by ultrafiltration and isopycnic centrifugation.

    Science.gov (United States)

    Guskey, L E; Wolff, D A

    1972-07-01

    A method is described by which poliovirus can be rapidly and simply concentrated by the use of a Diaflo XM-50 ultrafilter membrane. Freon-extracted ultrafilter concentrates banded in CsCl provided a 1,724-fold volumetric concentration of poliovirus. During concentration, trypsin-digested cellular material can pass through the ultrafilter membrane, thus providing a versatile means of degrading and eliminating extraneous contaminating proteins. The ultrafilter concentration system is compared with the CsCl cushion system of poliovirus concentration, and both systems are further compared by banding virus and virus capsid material in CsCl by use of isopycnic centrifugation. PMID:4341520

  19. 通用离心风机参数化设计系统的开发%Development of a Parametric Design System for Centrifugal Fan

    Institute of Scientific and Technical Information of China (English)

    李锐; 许敏; 陈雷

    2014-01-01

    Based on parametric design theory of fan, the parametric modeling and drawing software modules for main parts of fan is developed with the combination of SolidWorks and Visual Basic, which realized the CAD system for fan with combination of parametric 3D modeling and 2D engineering drawing. The system has characteristics of good generalization, simple operation and good maintainability, friendly interface and easy to operate. It can significantly shorten the research and development cycle, improve fan design efficiency and realize fan design automation.%以通风机参数化设计理论为基础,结合三维建模软件 SolidWorks 和面向对象的 Visual Basic语言开发出通风机主要零部件的参数化造型和制图软件模块,实现了通风机参数化三维造型与二维工程图纸绘制相结合的通风机CAD系统。该系统通用性强,可维护性好,界面友好,操作方便,可显著缩短风机研发周期,提高风机设计效率,实现风机设计自动化。

  20. Modeling on Fluid Flow and Inclusion Motion in Centrifugal Continuous Casting Strands

    Science.gov (United States)

    Wang, Qiangqiang; Zhang, Lifeng; Sridhar, Seetharaman

    2016-08-01

    During the centrifugal continuous casting process, unreasonable casting parameters can cause violent level fluctuation, serious gas entrainment, and formation of frozen shell pieces at the meniscus. Thus, in the current study, a three-dimensional multiphase turbulent model was established to study the transport phenomena during centrifugal continuous casting process. The effects of nozzle position, casting and rotational speed on the flow pattern, centrifugal force acting on the molten steel, level fluctuation, gas entrainment, shear stress on mold wall, and motion of inclusions during centrifugal continuous casting process were investigated. Volume of Fluid model was used to simulate the molten steel-air two-phase. The level fluctuation and the gas entrainment during casting were calculated by user-developed subroutines. The trajectory of inclusions in the rotating system was calculated using the Lagrangian approach. The results show that during centrifugal continuous casting, a large amount of gas was entrained into the molten steel, and broken into bubbles of various sizes. The greater the distance to the mold wall, the smaller the centrifugal force. Rotation speed had the most important influence on the centrifugal force distribution at the side region. Angular moving angle of the nozzle with 8° and keeping the rotation speed with 60 revolutions per minute can somehow stabilize the level fluctuation. The increase of angular angle of nozzle from 8 to 18 deg and rotation speed from 40 to 80 revolutions per minute favored to decrease the total volume of entrained bubbles, while the increase of distance of nozzle moving left and casting speed had reverse effects. The trajectories of inclusions in the mold were irregular, and then rotated along the strand length. After penetrating a certain distance, the inclusions gradually moved to the center of billet and gathered there. More work, such as the heat transfer, the solidification, and the inclusions entrapment

  1. Centrifugal acceleration in the magnetotail lobes

    Directory of Open Access Journals (Sweden)

    H. Nilsson

    2010-02-01

    Full Text Available Combined Cluster EFW and EDI measurements have shown that cold ion outflow in the magnetospheric lobes dominates the hydrogen ion outflow from the Earth's atmosphere. The ions have too low kinetic energy to be measurable with particle instruments, at least for the typical spacecraft potential of a sunlit spacecraft in the tenuous lobe plasmas outside a few RE. The measurement technique yields both density and bulk velocity, which can be combined with magnetic field measurements to estimate the centrifugal acceleration experienced by these particles. We present a quantitative estimate of the centrifugal acceleration, and the velocity change with distance which we would expect due to centrifugal acceleration. It is found that the centrifugal acceleration is on average outward with an average value of about of 5 m s−2. This is small, but acting during long transport times and over long distances the cumulative effect is significant, while still consistent with the relatively low velocities estimated using the combination of EFW and EDI data. The centrifugal acceleration should accelerate any oxygen ions in the lobes to energies observable by particle spectrometers. The data set also put constraints on the effectiveness of any other acceleration mechanisms acting in the lobes, where the total velocity increase between 5 and 19 RE geocentric distance is less than 5 km s−1.

  2. Roller and Centrifugal Pumps: A Retrospective Comparison of Bleeding Complications in Extracorporeal Membrane Oxygenation.

    Science.gov (United States)

    Halaweish, Ihab; Cole, Adam; Cooley, Elaine; Lynch, William R; Haft, Jonathan W

    2015-01-01

    Centrifugal pumps are increasingly used for extracorporeal membrane oxygenation (ECMO) rather than roller pumps. However, shear forces induced by these types of continuousflow pumps are associated with acquired von Willebrand factor deficiency and bleeding complications. This study was undertaken to compare adverse bleeding complications with the use of centrifugal and roller pumps in patients on prolonged ECMO support. The records of all adult ECMO patients from June 2002 to 2013 were retrospectively reviewed using the University of Michigan Health System database and the Extracorporeal Life Support Organization registry, focusing on patients supported for at least 5 days. Ninety-five ECMO patients met criteria for inclusion (48 roller vs. 47 centrifugal pump). Indications included pulmonary (79%), cardiac (15%), and extracorporeal cardiopulmonary resuscitation (6%), without significant difference between the two groups. Despite lower heparin anticoagulation (10.9 vs. 13.7 IU/kg/hr) with centrifugal pumps, there was a higher incidence of nonsurgical bleeding (gastrointestinal, pulmonary, and neurological) in centrifugal pump patients (26.1 vs. 9.0 events/1,000 patient-days, p = 0.024). In conclusion, in our historical comparison, despite reduced anticoagulation, ECMO support using centrifugal pumps was associated with a higher incidence of nonsurgical bleeding. The mechanisms behind this are multifactorial and require further investigation.

  3. Feasibility of a Short-Arm Centrifuge for Mouse Hypergravity Experiments.

    Directory of Open Access Journals (Sweden)

    Hironobu Morita

    Full Text Available To elucidate the pure impact of microgravity on small mammals despite uncontrolled factors that exist in the International Space Station, it is necessary to construct a 1 g environment in space. The Japan Aerospace Exploration Agency has developed a novel mouse habitat cage unit that can be installed in the Cell Biology Experiment Facility in the Kibo module of the International Space Station. The Cell Biology Experiment Facility has a short-arm centrifuge to produce artificial 1 g gravity in space for mouse experiments. However, the gravitational gradient formed inside the rearing cage is larger when the radius of gyration is shorter; this may have some impact on mice. Accordingly, biological responses to hypergravity induced by a short-arm centrifuge were examined and compared with those induced by a long-arm centrifuge. Hypergravity induced a significant Fos expression in the central nervous system, a suppression of body mass growth, an acute and transient reduction in food intake, and impaired vestibulomotor coordination. There was no difference in these responses between mice raised in a short-arm centrifuge and those in a long-arm centrifuge. These results demonstrate the feasibility of using a short-arm centrifuge for mouse experiments.

  4. Roller and Centrifugal Pumps: A Retrospective Comparison of Bleeding Complications in Extracorporeal Membrane Oxygenation.

    Science.gov (United States)

    Halaweish, Ihab; Cole, Adam; Cooley, Elaine; Lynch, William R; Haft, Jonathan W

    2015-01-01

    Centrifugal pumps are increasingly used for extracorporeal membrane oxygenation (ECMO) rather than roller pumps. However, shear forces induced by these types of continuousflow pumps are associated with acquired von Willebrand factor deficiency and bleeding complications. This study was undertaken to compare adverse bleeding complications with the use of centrifugal and roller pumps in patients on prolonged ECMO support. The records of all adult ECMO patients from June 2002 to 2013 were retrospectively reviewed using the University of Michigan Health System database and the Extracorporeal Life Support Organization registry, focusing on patients supported for at least 5 days. Ninety-five ECMO patients met criteria for inclusion (48 roller vs. 47 centrifugal pump). Indications included pulmonary (79%), cardiac (15%), and extracorporeal cardiopulmonary resuscitation (6%), without significant difference between the two groups. Despite lower heparin anticoagulation (10.9 vs. 13.7 IU/kg/hr) with centrifugal pumps, there was a higher incidence of nonsurgical bleeding (gastrointestinal, pulmonary, and neurological) in centrifugal pump patients (26.1 vs. 9.0 events/1,000 patient-days, p = 0.024). In conclusion, in our historical comparison, despite reduced anticoagulation, ECMO support using centrifugal pumps was associated with a higher incidence of nonsurgical bleeding. The mechanisms behind this are multifactorial and require further investigation. PMID:25914954

  5. Centrifugal compressor design for electrically assisted boost

    Science.gov (United States)

    Y Yang, M.; Martinez-Botas, R. F.; Zhuge, W. L.; Qureshi, U.; Richards, B.

    2013-12-01

    Electrically assisted boost is a prominent method to solve the issues of transient lag in turbocharger and remains an optimized operation condition for a compressor due to decoupling from turbine. Usually a centrifugal compressor for gasoline engine boosting is operated at high rotational speed which is beyond the ability of an electric motor in market. In this paper a centrifugal compressor with rotational speed as 120k RPM and pressure ratio as 2.0 is specially developed for electrically assisted boost. A centrifugal compressor including the impeller, vaneless diffuser and the volute is designed by meanline method followed by 3D detailed design. Then CFD method is employed to predict as well as analyse the performance of the design compressor. The results show that the pressure ratio and efficiency at design point is 2.07 and 78% specifically.

  6. Centrifugal compressor design for electrically assisted boost

    International Nuclear Information System (INIS)

    Electrically assisted boost is a prominent method to solve the issues of transient lag in turbocharger and remains an optimized operation condition for a compressor due to decoupling from turbine. Usually a centrifugal compressor for gasoline engine boosting is operated at high rotational speed which is beyond the ability of an electric motor in market. In this paper a centrifugal compressor with rotational speed as 120k RPM and pressure ratio as 2.0 is specially developed for electrically assisted boost. A centrifugal compressor including the impeller, vaneless diffuser and the volute is designed by meanline method followed by 3D detailed design. Then CFD method is employed to predict as well as analyse the performance of the design compressor. The results show that the pressure ratio and efficiency at design point is 2.07 and 78% specifically

  7. Neuro-Motor Responses to Daily Centrifugation in Bed-Rested Subjects

    Science.gov (United States)

    Reschke, Millard F.; Somers, Jeffery T.; Krnavek, Jody; Fisher, Elizibeth; Ford, George; Paloski, William H.

    2007-01-01

    It is well known from numerous space flight studies that exposure to micro-g produces both morphological and neural adaptations in the major postural muscles. However, the characteristics and mechanism of these changes, particularly when it may involve the central nervous system are not defined. Furthermore, it is not known what role unloading of the muscular system may have on central changes in sensorimotor function or if centrifugation along the +Gz direction (long body axis) can mitigate both the peripheral changes in muscle function and modification of the central changes in sensorimotor adaptation to the near weightless environment of space flight. The purpose of this specific effort was, therefore, to investigate the efficacy of artificial gravity (AG) as a method for maintaining sensorimotor function in micro-g. Eight male subjects were exposed to daily 1 hr centrifugation during a 21 day 6 degree head-down bed rest study. Seven controls were placed on the centrifuge without rotation. The radius and angular velocity of the centrifuge were adjusted such that each subject experienced a centripetal acceleration of 2.5g at the feet, and approximately 1.0g at the heart. Both the tendon (MSR) and functional stretch reflexes (FSR) were collected using an 80 lb. ft. servomotor controlled via position feedback to provide a dorsiflexion step input to elicit the MSR, and the same step input with a built in 3 sec hold to evoke the FSR. EMG data were obtained from the triceps surae. Supplementary torque, velocity and position data were collected with the EMG responses. All data were digitized and sampled at 4 kHz. Only the MSR data has been analyzed at this time, and preliminary results suggest that those subjects exposed to active centrifugation (treatment group) show only minor changes in MSR peak latency times, either as a function of time spent in bed rest or exposure to centrifugation, while the control subjects show delays in the MSR peak latencies that are

  8. Wave-Driven Rotation In Centrifugal Mirrors

    International Nuclear Information System (INIS)

    Centrifugal mirrors use supersonic rotation to provide axial confinement and enhanced stability. Usually the rotation is produced using electrodes, but these electrodes have limited the rotation to the Alfven critical ionization velocity, which is too slow to be useful for fusion. Instead, the rotation could be produced using radio frequency waves. A fixed azimuthal ripple is a simple and efficient wave that could produce rotation by harnessing alpha particle energy. This is an extension of the alpha channeling effect. The alpha particle power and efficiency in a simulated devices is sufficient to produce rotation without external energy input. By eliminating the need for electrodes, this opens new opportunities for centrifugal traps.

  9. Centrifugal Sieve for Size-Segregation/ Beneficiation of Regolith Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Utilizing centrifugal force as the primary body-force, combined with both shearing flow and vibratory motion the proposed centrifugal-sieve separators can provide...

  10. Design Optimization of Centrifugal Pump Using Radial Basis Function Metamodels

    OpenAIRE

    Yu Zhang; Jinglai Wu; Yunqing Zhang; Liping Chen

    2014-01-01

    Optimization design of centrifugal pump is a typical multiobjective optimization (MOO) problem. This paper presents an MOO design of centrifugal pump with five decision variables and three objective functions, and a set of centrifugal pumps with various impeller shroud shapes are studied by CFD numerical simulations. The important performance indexes for centrifugal pump such as head, efficiency, and required net positive suction head (NPSHr) are investigated, and the results indicate that th...

  11. Experimental Study on Series Operation of Sliding Vane Pump and Centrifugal Pump

    Directory of Open Access Journals (Sweden)

    Tao Li

    2013-01-01

    Full Text Available A platform for sliding vane pump and centrifugal pump tests is installed to study the series operation of them under different characteristics of pipeline. Firstly, the sliding vane pump and the centrifugal pump work independently, and the performance is recorded. Then, the two types of pumps are combined together, with the sliding vane pump acting as the feeding pump. Comparison is made between the performance of the independently working pump and the performance of series operation pump. Results show that the system flow rate is determined by the sliding vane pump. In order to ensure the stability of the series operation pumping system, the energy consumption required by the pipeline under the system flow should be greater than the pressure energy centrifugal pump can generate. Otherwise, the centrifugal pump can not operate stably, with reflux, swirl, gas-liquid two-phase flow in the runner and strong vibration and noise. The sliding vane pump can be in serial operation with the centrifugal pump under limited conditions.

  12. APPLICATION ANALYSIS REPORT: RETECH PLASMA CENTRIFUGAL FURNACE

    Science.gov (United States)

    This document is an evaluation of the performance of the Retech, Inc. Plasma Centrifugal Furnace (PCF) and its applicability as a treatment for soils contaminated with organic and/or inorganic compounds. Both the technical and economic aspectsof the technology were examined. A...

  13. Centrifugal Pump Experiment for Chemical Engineering Undergraduates

    Science.gov (United States)

    Vanderslice, Nicholas; Oberto, Richard; Marrero, Thomas R.

    2012-01-01

    The purpose of this paper is to describe a Centrifugal Pump Experiment that provided an experiential learning experience to chemical engineering undergraduates at the University of Missouri in the spring of 2010 in the Unit Operations Laboratory course. Lab equipment was used by senior students with computer-based data and control technology. In…

  14. Positive feedback stabilization of centrifugal compressor surge

    NARCIS (Netherlands)

    Willems, Frank; Heemels, W.P.M.H.; Jager, de Bram; Stoorvogel, Anton A.

    2002-01-01

    Stable operation of axial and centrifugal compressors is limited towards low mass flows due to the occurrence of surge. The stable operating region can be enlarged by active control. In this study, we use a control valve which is fully closed in the desired operating point and only opens to stabiliz

  15. Flow Pattern Characterization for a Centrifugal Impeller

    Science.gov (United States)

    Benavides, Efrén M.

    2014-08-01

    This paper proposes a model for characterizing the flow pattern of a centrifugal impeller attending to the severity of the reverse flow. The model assumes 1) a definition of an escaping particle as the one that flows in every operational point from the trailing edge towards the leading edge of the impeller blades, and 2) a characterization of flow where an operational point is said to have a theoretical flow pattern if it is not possible to establish a fully-reversed escaping particle on it. Therefore, the first part of the article is focused on defining an escaping particle for a centrifugal compressor. The model locates over the map of a centrifugal impeller the line that splits the map in two regions: the region on the right hand side, where a theoretical flow pattern can exist, and the region on the left, where a theoretical flow pattern cannot exist. Therefore, the locus of this line marks a frontier where the expected performance of the impeller cannot be sustained as high as expected. The second part of the article uses a high-performance commercial centrifugal impeller wheel for contrasting the model. A qualitative characterization of the surge line, conclusions and discussions are presented.

  16. 14 CFR 35.35 - Centrifugal load tests.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Centrifugal load tests. 35.35 Section 35.35... STANDARDS: PROPELLERS Tests and Inspections § 35.35 Centrifugal load tests. The applicant must demonstrate... to twice the maximum centrifugal load to which the propeller would be subjected during operation...

  17. Bacterial Cell Surface Damage Due to Centrifugal Compaction

    NARCIS (Netherlands)

    Peterson, Brandon W.; Sharma, Prashant K.; van der Mei, Henny C.; Busscher, Henk J.

    2012-01-01

    Centrifugal damage has been known to alter bacterial cell surface properties and interior structures, including DNA. Very few studies exist on bacterial damage caused by centrifugation because of the difficulty in relating centrifugation speed and container geometry to the damage caused. Here, we pr

  18. Physical modelling of earthquakes in the LCPC centrifuge

    OpenAIRE

    CHAZELAS, JL; Derkx, F.; THOREL, L; Escoffier, S.; Rault, G; BUTTIGIEG, S; COTTINEAU, LM; J. Garnier

    2006-01-01

    This paper presents a set of three new equipments that will enable next the Laboratoire Central des Ponts et Chaussées (LCPC - Nantes - France) to carry out reduced scale physical modeling in the centrifuge for earthquake engineering researches and testing. An earthquake simulator (EQS), designed by ACTIDYN Systems, will enable to apply as well sinus inputs in a wide band of frequencies as real or synthesis earthquakes at the bottom of soil models. This EQS is mono axial and its originality s...

  19. LISSAT Analysis of a Generic Centrifuge Enrichment Plant

    Energy Technology Data Exchange (ETDEWEB)

    Lambert, H; Elayat, H A; O?Connell, W J; Szytel, L; Dreicer, M

    2007-05-31

    The U.S. Department of Energy (DOE) is interested in developing tools and methods for use in designing and evaluating safeguards systems for current and future plants in the nuclear power fuel cycle. The DOE is engaging several DOE National Laboratories in efforts applied to safeguards for chemical conversion plants and gaseous centrifuge enrichment plants. As part of the development, Lawrence Livermore National Laboratory has developed an integrated safeguards system analysis tool (LISSAT). This tool provides modeling and analysis of facility and safeguards operations, generation of diversion paths, and evaluation of safeguards system effectiveness. The constituent elements of diversion scenarios, including material extraction and concealment measures, are structured using directed graphs (digraphs) and fault trees. Statistical analysis evaluates the effectiveness of measurement verification plans and randomly timed inspections. Time domain simulations analyze significant scenarios, especially those involving alternate time ordering of events or issues of timeliness. Such simulations can provide additional information to the fault tree analysis and can help identify the range of normal operations and, by extension, identify additional plant operational signatures of diversions. LISSAT analyses can be used to compare the diversion-detection probabilities for individual safeguards technologies and to inform overall strategy implementations for present and future plants. Additionally, LISSAT can be the basis for a rigorous cost-effectiveness analysis of safeguards and design options. This paper will describe the results of a LISSAT analysis of a generic centrifuge enrichment plant. The paper will describe the diversion scenarios analyzed and the effectiveness of various safeguards systems alternatives.

  20. Clinical use of centrifugal pumps and the roller pump in open heart surgery: a comparative evaluation.

    Science.gov (United States)

    Yoshikai, M; Hamada, M; Takarabe, K; Okazaki, Y; Ito, T

    1996-06-01

    Centrifugal pumps have been used widely as the main pump in open heart surgery to reduce damage to blood elements and to reduce the activation of the coagulation system. The purpose of this study was the evaluation and comparison of the effects of two types of centrifugal pumps and of one type of roller pump on blood elements, the coagulation system, complements, and immunoglobulins. Two types of centrifugal pumps (Lifestream; St. Jude Medical, Chelmsford, Massachusetts; and BP-80: Medtronic, BioMedicus, Inc., Eden Prairie, Minnesota, U.S.A.) and one roller pump (Mera Co.) were used separately as the main pump for cardiopulmonary bypass (CPB) in 29 patients. Platelet counts, lactate dehydrogenase, antithrombin III, thrombin-antithrombin complex (TAT), complements (C3, C4, and CH50) and immunoglobulins G, A, and M values were measured before and after CPB and compared. Values, except those for TAT, showed no significant difference among the three groups. The TAT values increased less in each of the centrifugal pump groups than in the roller pump group. This finding suggests that thrombin synthesis might be suppressed by the use of a centrifugal pump.

  1. Direct calculation of acceleration field through homogeneous transformation for two-axis centrifuge

    Institute of Scientific and Technical Information of China (English)

    吴广玉; 任顺清; 陈希军

    2003-01-01

    A precision centrifuge is an inertial navigation test equipment used for calibrating the characteristicsof accelerometers with high overloading, and a two-axis centrifuge can be used to generate either constant accel-eration or harmonic acceleration. The moving trajectory equation about the origin of the accelerometer coordinatesystem in a two-axis centrifuge was directly deduced through homogeneous transformation. The acceleration vec-tor of the origin in accelerometer coordinate system was achieved by making the second derivative of this trajec-tory equation. The acceleration components were acquired by decomposing this acceleration vector along thethree axes of the accelerometer coordinate system. The correctness of the homogeneous transformation was veri-fied through vector analysis.

  2. Methodology for optimally sized centrifugal partition chromatography columns.

    Science.gov (United States)

    Chollet, Sébastien; Marchal, Luc; Jérémy Meucci; Renault, Jean-Hugues; Legrand, Jack; Foucault, Alain

    2015-04-01

    Centrifugal Partition Chromatography (CPC) is a separation process based on the partitioning of solutes between two partially miscible liquid phases. There is no solid support for the stationary phase. The centrifugal acceleration is responsible for both stationary phase retention and mobile phase dispersion. CPC is thus a process based on liquid-liquid mass transfer. The separation efficiency is mainly influenced by the hydrodynamics of the phases in each cell of the column. Thanks to a visualization system, called "Visual CPC", it was observed that the mobile phase can flow through the stationary phase as a sheet, or a spray. Hydrodynamics, which directly governs the instrument efficiency, is directly affected during scale changes, and non-linear phenomena prevent the successful achievement of mastered geometrical scale changes. In this work, a methodology for CPC column sizing is proposed, based on the characterization of the efficiency of advanced cell shapes, taking into account the hydrodynamics. Knowledge about relationship between stationary phase volume, cell efficiency and separation resolution in CPC allowed calculating the optimum cell number for laboratory and industrial scale CPC application. The methodology is highlighted with results on five different geometries from 25 to 5000 mL, for two applications: the separation of alkylbenzene by partitioning with heptane/methanol/water biphasic system; and the separation of peptides by partitioning with n-butanol/acetic acid/water (4/1/5) biphasic system. With this approach, it is possible to predict the optimal CPC column length leading to highest productivity.

  3. Effects of centrifugal and Coriolis forces on the mold-filling behavior of titanium melts in vertically rotating molds

    Institute of Scientific and Technical Information of China (English)

    Xu Daming; Jia Limin; Fu Hengzhi

    2008-01-01

    The vertical centrifugal-casting technique is widely used in the manufacture of various irregularly-shaped castings of advanced structural alloys with thin walls, complex shapes and/or large sizes. These castings are used in the increasing applications in aero-space/aviation industries, human teeth/bone repairs with near-net shaped components, etc. In a vertically rotating casting system, the mold-filling processes of alloy melts, coupled with solidification-heat transfer, may be much more complicated, because they are driven simultaneously by gravity, centrifugal and Codolis forces. In the present work, an N-S/VOF-equations-based model, solved using a SOLA-VOF algorithm, under a rotating coordinate system was applied to numerically investigate the impacts of centrifugal and Coriolis forces on metallic melt mold-filling processes in different vertical centrifugal-casting configurations with different mold-rotation rates using an authors' computer-codes system. The computational results show that the Coriolis force may cause remarkable variations in the flow patterns in the casting-part-cavities of a large horizontal-section area and directly connected to the sprue via a short ingate in a vertical centrifugal-casting process. A "turn-back" mold-filling technique, which only takes advantage of the centrifugal force in a transient rotating melt system, has been confirmed to be a rational centrifugal-casting process in order to achieve smooth and layer-by-layer casting-cavities-filling control. The simulated mold-filling processes of Ti-6Al-4V alloy melt, in a vertical centrifugal-casting system with horizontally-connected plate-casting cavities, show reasonable agreement with experimental results from the literature.

  4. 国产离心式氯气压缩机的使用情况%Application of domestic centrifugal chlorine compressor

    Institute of Scientific and Technical Information of China (English)

    王增艳; 宋爱华; 张玉莲

    2012-01-01

    The working principle, structural performance and its auxiliary systems of centrifugal chlorine compressors was outlined .Maintenance and use of centrifugal chlorine compressors was introduced.%简述了离心式氯气压缩机的工作原理、结构性能、辅助系统及维护使用情况。

  5. Meridional Considerations of the Centrifugal Compressor Development

    Directory of Open Access Journals (Sweden)

    C. Xu

    2012-01-01

    Full Text Available Centrifugal compressor developments are interested in using optimization procedures that enable compressor high efficiency and wide operating ranges. Recently, high pressure ratio and efficiency of the centrifugal compressors require impeller design to pay attention to both the blade angle distribution and the meridional profile. The geometry of the blades and the meridional profile are very important contributions of compressor performance and structure reliability. This paper presents some recent studies of meridional impacts of the compressor. Studies indicated that the meridional profiles of the impeller impact the overall compressor efficiency and pressure ratio at the same rotational speed. Proper meridional profiles can improve the compressor efficiency and increase the overall pressure ratio at the same blade back curvature.

  6. Reconstitution of Human Ion Channels into Solvent-free Lipid Bilayers Enhanced by Centrifugal Forces.

    Science.gov (United States)

    Hirano-Iwata, Ayumi; Ishinari, Yutaka; Yoshida, Miyu; Araki, Shun; Tadaki, Daisuke; Miyata, Ryusuke; Ishibashi, Kenichi; Yamamoto, Hideaki; Kimura, Yasuo; Niwano, Michio

    2016-05-24

    Artificially formed bilayer lipid membranes (BLMs) provide well-defined systems for functional analyses of various membrane proteins, including ion channels. However, difficulties associated with the integration of membrane proteins into BLMs limit the experimental efficiency and usefulness of such BLM reconstitution systems. Here, we report on the use of centrifugation to more efficiently reconstitute human ion channels in solvent-free BLMs. The method improves the probability of membrane fusion. Membrane vesicles containing the human ether-a-go-go-related gene (hERG) channel, the human cardiac sodium channel (Nav1.5), and the human GABAA receptor (GABAAR) channel were formed, and the functional reconstitution of the channels into BLMs via vesicle fusion was investigated. Ion channel currents were recorded in 67% of the BLMs that were centrifuged with membrane vesicles under appropriate centrifugal conditions (14-55 × g). The characteristic channel properties were retained for hERG, Nav1.5, and GABAAR channels after centrifugal incorporation into the BLMs. A comparison of the centrifugal force with reported values for the fusion force revealed that a centrifugal enhancement in vesicle fusion was attained, not by accelerating the fusion process but by accelerating the delivery of membrane vesicles to the surface of the BLMs, which led to an increase in the number of membrane vesicles that were available for fusion. Our method for enhancing the probability of vesicle fusion promises to dramatically increase the experimental efficiency of BLM reconstitution systems, leading to the realization of a BLM-based, high-throughput platform for functional assays of various membrane proteins.

  7. Droplet centrifugation, droplet DNA extraction, and rapid droplet thermocycling for simpler and faster PCR assay using wire-guided manipulations

    OpenAIRE

    You David J; Yoon Jeong-Yeol

    2012-01-01

    Abstract A computer numerical control (CNC) apparatus was used to perform droplet centrifugation, droplet DNA extraction, and rapid droplet thermocycling on a single superhydrophobic surface and a multi-chambered PCB heater. Droplets were manipulated using “wire-guided” method (a pipette tip was used in this study). This methodology can be easily adapted to existing commercial robotic pipetting system, while demonstrated added capabilities such as vibrational mixing, high-speed centrifuging o...

  8. Determination of Wear That Can be Formed at the Stainless Steel Wheels of the Centrifuge Pumps Used at Agricultural Irrigation

    OpenAIRE

    Yuksel, E; B. Eker

    2009-01-01

    The extent of this work is operating characteristics of a horizontal shafted centrifugal pump (which has stainless steel wheel) which has been operated for 7 hours on the average. A closed circuit pump system (circulating within itself) which was formed by attaching a horizontal shafted centrifugal pump which can be used in irrigation applications with a drum has been operated for 150 hours at laboratory conditions. To define the operating properties of the pump, its operating characteristics...

  9. Component Analysis of Unsteady Hydrodynamic Force of Closed-Type Centrifugal Pump with Single Blades of Different Blade Outlet Angles

    OpenAIRE

    Yasuyuki Nishi; Junichiro Fukutomi

    2015-01-01

    Single-blade centrifugal impellers for sewage systems undergo both unsteady radial and axial thrusts. Therefore, it is extremely important for the improvement of pump reliability to quantitatively grasp these fluctuating hydrodynamic forces and determine the generation mechanism behind them. In this study, we conducted component analyses of radial and axial thrusts of closed, single-blade centrifugal pumps with different blade outlet angles by numerical analysis while considering leakage flow...

  10. Centrifuge modeling of soil atmosphere interaction

    OpenAIRE

    CAICEDO, B; TRISTANCHO, J; THOREL, Luc

    2010-01-01

    Atmosphere process of infiltration or evaporation affect the behavior of geotechnical structures located near the soil surface. This paper focuses on the drying process of soils due to evaporation. The scaling laws are analyzed and afterwards the results on applying two cycles of heating and cooling on a soil mass are presented. Based on these results, conclusions about the feasibility of reproducing evaporation on centrifuge models are recommended.

  11. Aerodynamic instabilities in transonic centrifugal compressor

    OpenAIRE

    Buffaz, Nicolas; Trébinjac, Isabelle

    2014-01-01

    International audience This paper presents the analysis of the instabilities inception in a transonic centrifugal com-pressor for different rotation speeds. The analysis was conducted from experimental results obtained with unsteady pressure sensors implanted in the inducer, vaneless diffuser and vaned diffuser. Beyond the stability limit the compressor enters into a deep surge without any precursor, whatever the speed. The surge process is initiated in the vaned diffuser by a massive boun...

  12. Submarine landslide flows simulation through centrifuge modelling

    OpenAIRE

    Gue, Chang Shin

    2012-01-01

    Landslides occur both onshore and offshore. However, little attention has been given to offshore landslides (submarine landslides). Submarine landslides have significant impacts and consequences on offshore and coastal facilities. The unique characteristics of submarine landslides include large mass movements and long travel distances at very gentle slopes. This thesis is concerned with developing centrifuge scaling laws for submarine landslide flows through the study of modell...

  13. Development of centrifuge modelling in geotechnics

    OpenAIRE

    J. Garnier

    2006-01-01

    In order to satisfy similitude conditions, physical modelling in the field of geotechnics requires major facilities, such as shaking tables, calibration chambers and centrifuges. The rapid expansion of centifuge modelling since the beginning of the 1980's can be explained by technological developments in computing, electronics and mechanics as well by enhanced knowledge in the areas of scaling laws, thanks to recent research work on both the properties of reconstituted soils and similitude co...

  14. Potential flow through centrifugal pumps and turbines

    Science.gov (United States)

    Sorensen, E

    1941-01-01

    The methods of conformal transformation up to the present have been applied to the potential flows in the rotation of solid bodies only to a limited extent. This report deals with aspects of centrifugal pumps and turbines such as: the complex potential for rotation, potential for the flow due to the blade rotation, velocities at the blade tip, comparison with "infinite number of blades," and a variable number of blades.

  15. CENTRIFUGAL VIBRATION TEST OF RC PILE FOUNDATION

    Science.gov (United States)

    Higuchi, Shunichi; Tsutsumiuchi, Takahiro; Otsuka, Rinna; Ito, Koji; Ejiri, Joji

    It is necessary that nonlinear responses of structures are clarified by soil-structure interaction analysis for the purpose of evaluating the seismic performances of underground structure or foundation structure. In this research, centrifuge shake table tests of reinforced concrete pile foundation installed in the liquefied ground were conducted. Then, finite element analyses for the tests were conducted to confirm an applicability of the analytical method by comparing the experimental results and analytical results.

  16. Gender Differences in Cardiovascular Tolerance to Short Arm Centrifugation

    Science.gov (United States)

    Fong, Kevin J.; Arya, Maneesh; Paloski, William H.

    2007-01-01

    In preparation for the NASA Artificial Gravity (AG) pilot study, the tolerability of the proposed AG parameters was tested in 11 ambulatory human subjects (6m, 5w) by exposing each to a short arm centrifuge trial. Subjects were oriented in the supine position (but inclined 6deg head down) on one arm of the centrifuge, and the rotation rate (30.6-33.4 rpm) and radial position of the feet were set to produce 2.5G of equivalent gravitational load at the force plate directly beneath the feet, 1G at the level of the mediastinum, and approximately 0.55G at the labyrinth. Amongst the 6 men participating in this preliminary study, 5 completed at least 60 minutes of the trial successfully with no adverse sequelae. However, amongst the female cohort the test was stopped by the medical monitor before 60 min in all but one case, with pre-syncope listed as the reason for termination in all cases. Mean time before abort of the centrifuge run amongst the women was 33.2 +/- 20.97 min. It is known that women have a greater predisposition to syncope during orthostatic stress, under normal tilt table conditions, during LBNP, and following space flight. The reasons for this difference are the subject of some debate, but anthropometric factors, the vasoactive effects of sex hormones, gender differences in susceptibility to motion sickness, catecholamine levels, ability to augment total peripheral resistance in response to orthostatic stress, and structural differences in cardiac anatomy and physiology have all been suggested. This finding led to the exclusion of women from the AG pilot study. Clearly if AG is to be employed as a multi-system countermeasure it must provide physiological protection at rotation rates within the tolerance limits of all potential astronauts. Further investigation of the responses of women to centrifugation will be necessary to determine how to adjust AG parameters for tolerance by female subjects before a more detailed investigation of the appropriate dose

  17. Numerical Study of a Fuel Centrifugal Pump with Variable Impeller Width for Aero-engines

    Science.gov (United States)

    Wang, Bin; Guan, Huasheng; Ye, Zhifeng

    2015-12-01

    As typical pump with large flow rate and high reliability, centrifugal pumps in fuel system of aero-engines mostly regulate flow rate by flow bypass, which leads to low efficiency and large fuel temperature rise especially at low flow rate. An innovative fuel centrifugal pump with variable impeller width is a more effective way to regulate flow rate than flow bypass. To find external characteristics of the centrifugal pump with variable impeller width proposed in this paper, flow domain within the pump is simulated numerically and some primary performance parameters and their correlation are analyzed. Results show that flow rate of the pump can be regulated by variable impeller width and that efficiency for this scheme is higher than that for flow bypass. The higher outlet static pressure the pump runs at, the wider range of flow rates can be obtained with stronger nonlinear relationship between flow rate and impeller width.

  18. Stable isotope enrichment using a plasma centrifuge

    Science.gov (United States)

    Krishnan, Mahadevan; Bures, Brian; Madden, Robert

    2012-10-01

    A primary goal of the Department of Energy's Isotope Development and Production for Research and Applications Program (Isotope Program) within the Office of Nuclear Physics (NP) is to produce isotopes that are in short supply in the U.S. and of which there exists no or insufficient domestic commercial production capability. A vacuum arc plasma centrifuge is a rigid rotor column of metal plasma in which centrifugal forces re-distribute ions radially according to their mass/charge ratio. Early work demonstrated rotation at 2 million rpm and separation of various stable isotopes. The spinning plasma column had a Gaussian flux profile, peaked on the rigid rotor axis. This work adopts a more efficient approach, with the plasma created as a hollow column, wherein the flux is concentrated at larger radii where the centrifugal action is highest. By tailoring the vacuum arc discharge geometry, the rotation rate can also be increased to ˜10 million rpm. Data from Cu, Al and other metal plasmas will be presented and discussed in light of enriched stable isotopes needed for research and medicine.

  19. CFD Simulation of Annular Centrifugal Extractors

    Directory of Open Access Journals (Sweden)

    S. Vedantam

    2012-01-01

    Full Text Available Annular centrifugal extractors (ACE, also called annular centrifugal contactors offer several advantages over the other conventional process equipment such as low hold-up, high process throughput, low residence time, low solvent inventory and high turn down ratio. The equipment provides a very high value of mass transfer coefficient and interfacial area in the annular zone because of the high level of power consumption per unit volume and separation inside the rotor due to the high g of centrifugal field. For the development of rational and reliable design procedures, it is important to understand the flow patterns in the mixer and settler zones. Computational Fluid Dynamics (CFD has played a major role in the constant evolution and improvements of this device. During the past thirty years, a large number of investigators have undertaken CFD simulations. All these publications have been carefully and critically analyzed and a coherent picture of the present status has been presented in this review paper. Initially, review of the single phase studies in the annular region has been presented, followed by the separator region. In continuation, the two-phase CFD simulations involving liquid-liquid and gas-liquid flow in the annular as well as separator regions have been reviewed. Suggestions have been made for the future work for bridging the existing knowledge gaps. In particular, emphasis has been given to the application of CFD simulations for the design of this equipment.

  20. Shallow water model for horizontal centrifugal casting

    Science.gov (United States)

    Boháček, J.; Kharicha, A.; Ludwig, A.; Wu, M.

    2012-07-01

    A numerical model was proposed to simulate the solidification process of an outer shell of work roll made by the horizontal centrifugal casting technique. Shallow water model was adopted to solve the 2D average flow dynamics of melt spreading and the average temperature distribution inside the centrifugal casting mould by considering the centrifugal force, Coriolis force, viscous force due to zero velocity on the mould wall, gravity, and energy transport by the flow. Additionally, a 1D sub-model was implemented to consider the heat transfer in the radial direction from the solidifying shell to the mould. The solidification front was tracked by fulfilling the Stefan condition. Radiative and convective heat losses were included from both, the free liquid surface and the outer wall of the mould. Several cases were simulated with the following assumed initial conditions: constant height of the liquid metal (10, 20, and 30 mm), uniform temperature of the free liquid surface (1755 K). The simulation results have shown that while the solidification front remained rather flat, the free surface was disturbed by waves. The amplitude of waves increased with the liquid height. Free surface waves diminished as the solidification proceeded.

  1. CFD Analysis of Centrifugal Pump: A Review

    Directory of Open Access Journals (Sweden)

    Narayan P. Jaiswal

    2014-05-01

    Full Text Available The main objective of this work is to understand role of the computational fluid dynamics (CFD technique in analyzing and predicting the performance of centrifugal pump. Computational Fluid Dynamics (CFD is the present day state-of-art technique for fluid flow analysis. The critical review of CFD analysis of CFD analysis of centrifugal pump along with future scope for further improvement is presented in this paper. Different solver like ANSYS-CFX, FLUENT etc can be used for simulations. Shear stress transport model has been found appropriate as turbulence model. Study of pressure contours, velocity contours, flow streamlines etc can be studied by CFD techniques. Unsteady Reynolds Averaged Navier Stokes (URANS equations are solved by solver to get flow simulation results inside centrifugal pump. CFD results has to be validated with testing results or with performance characteristics curves. Performance prediction at design and off-design conditions, parametric study, cavitation analysis, diffuser pump analysis, performance of pump running in turbine mode etc. are possible with CFD simulation techniques.

  2. Benefication of coking-coal slimes by means of screen centrifuges

    Energy Technology Data Exchange (ETDEWEB)

    S.A. Osadchii; E.K. Samoilova; G.Y. Gol' berg [Coal Preparation Plant Neryungrinskaya, Neryungri (Russian Federation)

    2009-06-15

    A new slime-benefication technology has been developed at Coal Preparation Plant Neryungrinskaya. In this technology, the product is separated in screen centrifuges. As a result, small particles with relatively high ash content are extracted in the centrifugate. Correspondingly, the cake has the required ash content of {le} 10%. Industrial tests indicate that this technology is feasible at the facility. The parameters that ensure most effective slime separation are determined. The new slime-benefication system is simple and characterized by relatively low operating costs: the expected reduction in production costs relative to the existing technology is about 126 million rub/yr.

  3. Centrifugal separation and equilibration dynamics in an electron-antiproton plasma

    CERN Document Server

    Andresen, G B; Baquero-Ruiz, Marcelo; Bertsche, William; Bowe, Paul D; Butler, Eoin; Cesar, Claudio L; Chapman, Steven; Charlton, Michael; Deller, A; Eriksson, S; Fajans, Joel; Friesen, Tim; Fujiwara, Makoto C; Gill, David R; Gutierrez, A; Hangst, Jeffrey S; Hardy, Walter N; Hayden, Michael E; Humphries, Andrew J; Hydomako, Richard; Jonsell, Svante; Madsen, Niels; Menary, Scott; Nolan, Paul; Olin, Art; Povilus, Alexander; Pusa, Petteri; Robicheaux, Francis; Sarid, Eli; Silveira, Daniel M; So, Chukman; Storey, James W; Thompson, Robert I; van der Werf, Dirk P; Wurtele, Jonathan S; Yamazaki, Yasunori

    2011-01-01

    Charges in cold, multiple-species, non-neutral plasmas separate radially by mass, forming centrifugally-separated states. Here, we report the first detailed measurements of such states in an electron-antiproton plasma, and the first observations of the separation dynamics in any centrifugally-separated system. While the observed equilibrium states are expected and in agreement with theory, the equilibration time is approximately constant over a wide range of parameters, a surprising and as yet unexplained result. Electron-antiproton plasmas play a crucial role in antihydrogen trapping experiments.

  4. Numerical studies of the velocity distribution within the volute of a centrifugal pump

    OpenAIRE

    Al-Obaidi, Ahmed; Pradhan, Suman; Asim, Taimoor; Mishra, Rakesh; Zala, Karina

    2014-01-01

    Centrifugal pumps play an essential role in engineering systems since they are widely used in the process and power industries. The performance of a centrifugal pump needs to be maximised due to its importance and this depends on the flow structure within the pump. The flow structure within a pump is very complex due to the presence of a rotating impeller and its interaction with the volute casing. In this paper, a numerical investigation using CFD analysis has been carried out to determine t...

  5. Numerical Study of Unsteady Flow in Centrifugal Cold Compressor

    Science.gov (United States)

    Zhang, Ning; Zhang, Peng; Wu, Jihao; Li, Qing

    In helium refrigeration system, high-speed centrifugal cold compressor is utilized to pumped gaseous helium from saturated liquid helium tank at low temperature and low pressure for producing superfluid helium or sub-cooled helium. Stall and surge are common unsteady flow phenomena in centrifugal cold compressors which severely limit operation range and impact efficiency reliability. In order to obtain the installed range of cold compressor, unsteady flow in the case of low mass flow or high pressure ratio is investigated by the CFD. From the results of the numerical analysis, it can be deduced that the pressure ratio increases with the decrease in reduced mass flow. With the decrease of the reduced mass flow, backflow and vortex are intensified near the shroud of impeller. The unsteady flow will not only increase the flow loss, but also damage the compressor. It provided a numerical foundation of analyzing the effect of unsteady flow field and reducing the flow loss, and it is helpful for the further study and able to instruct the designing.

  6. Design and Characterization of a Centrifugal Compressor Surge Test Rig

    Directory of Open Access Journals (Sweden)

    Kin Tien Lim

    2011-01-01

    Full Text Available A detailed description of a new centrifugal compressor surge test rig is presented. The objective of the design and development of the rig is to study the surge phenomenon in centrifugal compression systems and to investigate a novel method of surge control by active magnetic bearing servo actuation of the impeller axial tip clearance. In this paper, we focus on the design, initial setup, and testing of the rig. The latter two include the commissioning of the rig and the experimental characterization of the compressor performance. The behavior of the compressor during surge is analyzed by driving the experimental setup into surge. Two fundamental frequencies, 21 Hz and 7 Hz, connected to the surge oscillation in the test rig are identified, and the observed instability is categorized according to the intensity of pressure fluctuations. Based on the test results, the excited pressure waves are clearly the result of surge and not stall. Also, they exhibit the characteristics of mild and classic surge instead of deep surge. Finally, the change in the compressor performance due to variation in the impeller tip clearance is experimentally examined, and the results support the potential of the tip clearance modulation for the control of compressor surge. This is the first such demonstration of the feasibility of surge control of a compressor using active magnetic bearings.

  7. In-vitro assessment of centrifugal pumps for ventricular assist.

    Science.gov (United States)

    Jakob, H; Kutschera, Y; Palzer, B; Prellwitz, W; Oelert, H

    1990-08-01

    Currently two major types of centrifugal pumps are commercially available for ventricular assist: the Biomedicus-cone (Group I) and the Centrimed-impeller pump (now Sarns 3M) (Group II). To compare them for blood trauma and hemolysis, an in-vitro experiment was designed with a Stöckert roller pump as a standard control (Group III). The in-vitro circuit was constructed consisting of a pump head, electromagnetic flow probe, polyvinyl chloride tubing and a reservoir, identical for all groups. Human ACD blood was used for priming and was circulated with a flow rate of 2 L/min for 24 h. Blood samples were taken at 0, 1, 3, 6, 12, and 24 h and zero control values were subtracted from the resulting data per time interval. Among the 16 parameters studied, a highly significant difference in favor of Group I was found for glutamate oxalacetate transaminase (GOT) and lactate dehydrogenase (p less than 0.0001) and for the free plasma hemoglobin (p less than 0.0001) after 12 and 24 h, respectively. The hemolytic index (Allen) again was lowest for group I in contrast to Groups II and III (0.012 versus 0.060 and 1.70) after 24 h. All other parameters studied did not render significant differences between the systems tested. The authors conclude that the Biomedicus pump currently is the least traumatic centrifugal pump for ventricular assist.

  8. Platelet function and hemolysis in centrifugal pumps: in vitro investigations.

    Science.gov (United States)

    Steines, D; Westphal, D; Göbel, C; Reul, H; Rau, G

    1999-08-01

    The effects of centrifugal pumps on blood components other than erythrocytes, namely platelets and their interaction with the coagulation system, are not very well known. In a comparative study with three centrifugal pumps (BioMedicus BP-80, St. Jude Isoflow, and Sarns Delphin) and the Stockert roller pump hemolysis, platelet counts, thromboplastin and partial thromboplastin times, as well as resonance thrombography (RTG) parameters for the assessment of platelet and coagulation function were evaluated in vitro. Normalized indices of hemolysis (NIH) with ACD anticoagulation after 360 minutes were 0.008+/-0.004 (Isoflow), 0.018+/-0.017 (BP-80), 0.085+/-0.051 (Delphin), and 0.049+/-0.010 g/1001 (roller pump). Plasmatic coagulation was activated in all circuits. Platelet function was severely inhibited by the BP-80, indicated by increase in RTG platelet time to 358%+/-150% of initial values compared to 42%+/-29% (Isoflow), 40%+/-20% (Delphin), and 12%+/-10% (roller pump). Fibrin polymerization was affected similarly. The large surface area of the BP-80 leads to an extensive activation of platelets and plasminogen.

  9. Concrete Cleaning, Inc. centrifugal shot blaster: Baseline report; Greenbook (chapter)

    International Nuclear Information System (INIS)

    The centrifugal shot blaster technology was tested and is being evaluated at Florida International University (FIU) as a baseline technology. In conjunction with FIU's evaluation of efficiency and cost, this report covers the evaluation conducted for safety and health issues. It is a commercially available technology and has been used for various projects at locations throughout the country. The centrifugal shot blaster is an electronically operated shot blast machine that has been modified to remove layers of concrete to varying depths. A hardened steel shot propelled at a high rate of speed abrades the surface of the concrete. The depth of material removed is determined by the rate of speed the machine is traveling and the volume of shot being fired into the blast chamber. The steel shot is recycled and used over until it is pulverized into dust, which ends up in the waste container with the concrete being removed. Debris is continually vacuumed by a large dust collection system attached to the shot blaster. The safety and health evaluation during the human factors assessment focused on two main areas: noise and dust

  10. Model based fault diagnosis in a centrifugal pump application using structural analysis

    DEFF Research Database (Denmark)

    Kallesøe, C. S.; Izadi-Zamanabadi, Roozbeh; Rasmussen, Henrik;

    2004-01-01

    A model based approach for fault detection and isolation in a centrifugal pump is proposed in this paper. The fault detection algorithm is derived using a combination of structural analysis, Analytical Redundant Relations (ARR) and observer designs. Structural considerations on the system are used...

  11. Model Based Fault Diagnosis in a Centrifugal Pump Application using Structural Analysis

    DEFF Research Database (Denmark)

    Kallesøe, C. S.; Izadi-Zamanabadi, Roozbeh; Rasmussen, Henrik;

    2004-01-01

    A model based approach for fault detection and isolation in a centrifugal pump is proposed in this paper. The fault detection algorithm is derived using a combination of structural analysis, Analytical Redundant Relations (ARR) and observer designs. Structural considerations on the system are used...

  12. Cardio-postural interactions and short-arm centrifugation.

    Science.gov (United States)

    Blaber, Andrew; Goswami, Nandu; Xu, Da; Laurin, Alexendre

    INTRODUCTION: We are interested in mechanisms associated with orthostatic tolerance. In previous studies we have shown that postural muscles in the calf contribute to both posture and blood pressure regulation during orthostatic stress. In this study we investigated the relationship between cardiovascular and postural muscle control before, during and after short arm human centrifuge (SAHC) up to 2.2 G. METHODS: Eleven healthy young subjects (6 m, 5 f), with no history of cardiovascular disease, falls or orthostatic hypotension, participated. All were familiarized with the SAHC with 10 minutes at 1-G at the feet. Each subject was instrumented in the supine position on the SAHC for beat-to-beat ECG and blood pressure (Portapres derived SBP). Bilateral lower leg EMG was collected from four leg postural muscles: tibialis anterior, medial gastrocnemius, lateral gastrocnemius, and medial soleus. Transdermal differential recording of signals was performed using an 8-channel EMG system, (Myosystem 1200, Noraxon Inc., Arizona, USA). Postural sway data of the body COP was computed from the force and moment data collected with a force platform (Accusway, AMTI, MA, USA). Before and after SAHC, the subject stood on a force platform with their gaze fixed on a point at eye level, closed their eyes and stood quietly for 5 min. A final stand was conducted 30 min after centrifugation with supine rest in between. During clockwise centrifugation (10-min 1g and 10-min 2.2g at the foot) the subjects’ head was hooded and in the dark. The subject’s body was restrained into the rotation arm with a parachute harness and given additional body support with a foot-plate. ECG, EMG and BP data were collected throughout and centre of pressure trajectory (COP) collected during the stand test. Subjects were requested to relax and not to voluntarily contract the leg muscles; however, they were not to suppress contractions as they occurred involuntarily or by reflex. A Continuous Wavelet

  13. Pressure Pulsation Signal Analysis for Centrifugal Compressor Blade Crack Determination

    OpenAIRE

    Hongkun Li; Xuefeng Zhang; Xiaowen Zhang; Shuhua Yang; Fujian Xu

    2014-01-01

    Blade is a key piece of component for centrifugal compressor. But blade crack could usually occur as blade suffers from the effect of centrifugal forces, gas pressure, friction force, and so on. It could lead to blade failure and centrifugal compressor closing down. Therefore, it is important for blade crack early warning. It is difficult to determine blade crack as the information is weak. In this research, a pressure pulsation (PP) sensor installed in vicinity to the crack area is used to d...

  14. Numerical Investigations on the Transient Performance of a Centrifugal Pump

    OpenAIRE

    Asim, Taimoor; Mishra, Rakesh

    2015-01-01

    Centrifugal pumps are an integral part of plants used in process industries. The flow structure within a centrifugal pump is very complex due to the interaction between the rotating impeller and the geometric features around it. In the present study, numerical investigations on a centrifugal pump have been carried out using a Computational Fluid Dynamics (CFD) based solver. This study employs finite volume technique in order to analyse the influence of variations in the rotational speed of th...

  15. Latex Micro-balloon Pumping in Centrifugal Microfluidic Platforms

    OpenAIRE

    Aeinehvand, Mohammad Mahdi; Ibrahim, Fatimah; Al-Faqheri, Wisam; Thio, Tzer Hwai Gilbert; Kazemzadeh, Amin; Wadi harun, Sulaiman; Madou, Marc

    2014-01-01

    Centrifugal microfluidic platforms have emerged as point-of-care diagnostic tools. However, the unidirectional nature of the centrifugal force limits the available space for multi-stepped processes on a single microfluidics disc. To overcome this limitation, a passive pneumatic pumping method actuated at high rotational speeds has been previously proposed to pump liquid against the centrifugal force. In this paper, a novel micro-balloon pumping method that relies on elastic energy stored in a...

  16. Centrifugal Sieve for Gravity-Level-Independent Size Segregation of Granular Materials

    Science.gov (United States)

    Walton, Otis R.; Dreyer, Christopher; Riedel, Edward

    2013-01-01

    Conventional size segregation or screening in batch mode, using stacked vibrated screens, is often a time-consuming process. Utilization of centrifugal force instead of gravity as the primary body force can significantly shorten the time to segregate feedstock into a set of different-sized fractions. Likewise, under reduced gravity or microgravity, a centrifugal sieve system would function as well as it does terrestrially. When vibratory and mechanical blade sieving screens designed for terrestrial conditions were tested under lunar gravity conditions, they did not function well. The centrifugal sieving design of this technology overcomes the issues that prevented sieves designed for terrestrial conditions from functioning under reduced gravity. These sieves feature a rotating outer (cylindrical or conical) screen wall, rotating fast enough for the centrifugal forces near the wall to hold granular material against the rotating screen. Conventional centrifugal sieves have a stationary screen and rapidly rotating blades that shear the granular solid near the stationary screen, and effect the sieving process assisted by the airflow inside the unit. The centrifugal sieves of this new design may (or may not) have an inner blade or blades, moving relative to the rotating wall screen. Some continuous flow embodiments would have no inner auger or blades, but achieve axial motion through vibration. In all cases, the shearing action is gentler than conventional centrifugal sieves, which have very high velocity differences between the stationary outer screen and the rapidly rotating blades. The new design does not depend on airflow in the sieving unit, so it will function just as well in vacuum as in air. One advantage of the innovation for batch sieving is that a batch-mode centrifugal sieve may accomplish the same sieving operation in much less time than a conventional stacked set of vibrated screens (which utilize gravity as the primary driving force for size separation

  17. Separative power of an optimised concurrent gas centrifuge

    Energy Technology Data Exchange (ETDEWEB)

    Bogovalov, Sergey; Boman, Vladimir [National Research Nuclear University (MEPHI), Moscow (Russian Federation)

    2016-06-15

    The problem of separation of isotopes in a concurrent gas centrifuge is solved analytically for an arbitrary binary mixture of isotopes. The separative power of the optimised concurrent gas centrifuges for the uranium isotopes equals to δU = 12.7 (V/700 m/s)2(300 K/T)(L/1 m) kg·SWU/yr, where L and V are the length and linear velocity of the rotor of the gas centrifuge and T is the temperature. This equation agrees well with the empirically determined separative power of optimised counter-current gas centrifuges.

  18. [Design and optimization of a centrifugal pump for CPCR].

    Science.gov (United States)

    Pei, J; Tan, X; Chen, K; Li, X

    2000-06-01

    Requirements for an optimal centrifugal pump, the vital component in the equipment for cardiopulmonary cerebral resuscitation(CPCR), have been presented. The performance of the Sarns centrifugal pump (Sarns, Inc./3M, Ann arbor, MI, U.S.A) was tested. The preliminarily optimized model for CPCR was designed according to the requirements of CPCR and to the comparison and analysis of several clinically available centrifugal pumps. The preliminary tests using the centrifugal pump made in our laboratory(Type CPCR-I) have confirmed the design and the optimization.

  19. Computer simulation for centrifugal mold filling of precision titanium castings

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    Computer simulation codes were developed based on a proposed mathematical model for centrifugal mold filling processes and previous computer software for 3D mold filling and solidification of castings (CASM-3D for Windows). Sample simulations were implemented for mold filling processes of precision titanium castings under gravity and different centrifugal casting techniques. The computation results show that the alloy melt has a much stronger mold filling ability for thin section castings under a centrifugal force field than that only under the gravity. A "return back" mold filling manner is showed to be a reasonable technique for centrifugal casting processes, especially for thin section precision castings.

  20. Rotational spectroscopy with an optical centrifuge

    CERN Document Server

    Korobenko, Aleksey; Hepburn, John W; Milner, Valery

    2013-01-01

    We demonstrate a new spectroscopic method for studying electronic transitions in molecules with extremely broad range of angular momentum. We employ an optical centrifuge to create narrow rotational wave packets in the ground electronic state of $^{16}$O$_2$. Using the technique of resonance-enhanced multi-photon ionization, we record the spectrum of multiple ro-vibrational transitions between $X^3\\Sigma_{g}^{-}$ and $C^3\\Pi_{g}$ electronic manifolds of oxygen. Direct control of rotational excitation, extending to rotational quantum numbers as high as $N\\gtrsim 120$, enables us to interpret the complex structure of rotational spectra of $C^3\\Pi_{g}$ beyond thermally accessible levels.

  1. Gas centrifuge bibliography 1980-1982

    International Nuclear Information System (INIS)

    A bibliography, with abstract, is presented of the gas centrifuge literature published from 1980 to 1982 inclusive. It supplements PG Information Series 25 (CA), BNFL Information Series 15 (CA) and BNFL Information Series 23 (CA), which covered the periods 1895 to 1970, 1970 to 1974, and 1975 to 1979 respectively. After bibliographies and books and pamphlets, the main list is arranged chronologically under the headings, Reports, Journal articles, and Conference papers. Items omitted from the earlier bibliographies or received too late for inclusion in this, have been listed separately. There are author, report number and subject indexes. (U.K.)

  2. DESIGN PARAMETERS OF CENTRIFUGAL COMPRESSOR INDUCER

    Directory of Open Access Journals (Sweden)

    Saim KOÇAK

    1998-03-01

    Full Text Available Design characteristics of centrifugal compressor impellers working with compressible fluids are analyzed, and the design parameters of inducer are defined. The effects of incidence, deviation and deflection angles, relative eddy, rotating stall and Mach number are investigated. The relation between minimum relative Mach number of inducer and flow angle is investigated and it is observed that the minimum Mach number occurs for flow angle values between -680 and -520 . In the design, the effect of a 100 difference in flow angle is found to be less than 1 % on minimum relative Mach number.

  3. Rotordynamic Forces on Centrifugal Pump Impellers

    OpenAIRE

    Franz, R.; Arndt, N.; Caughey, T. K.; Brennen, C. E.; Acosta, A.J

    1987-01-01

    The asymmetric flow around an impeller in a volute exerts a force upon the impeller. To study the rotordynamic force on an impeller which is vibrating around its machine axis of rotation, the impeller, mounted on a dynamometer, is made to whirl in a circular orbit within the volute. The measured force is expressed as the sum of a steady radial force and an unsteady force due to the eccentric motion of the impeller. These forces were measured in separate tests on a centrifugal pump with rad...

  4. THERMODYNAMIC DESIGN OF CENTRIFUGAL COMPRESSOR FOR TURBOCHARGER

    OpenAIRE

    Sonawane Shubham*, Sondkar Pratik, Qasim Siddiqui, Phirke Indraneel, Prof. R. P. Kakde

    2016-01-01

    The purpose of a turbocharger is to increase the power output of an engine by supplying compressed air to the engine intake manifold so that fuel can be burnt efficiently. In this work, thermodynamic design of a high pressure ratio centrifugal compressor, for 75 kW class engines, was carried out. A pressure ratio of 2.8 was considered with a compressor rotational speed of 60,000 RPM. The compressor was designed for vane less diffuser. The impeller designs were obtained using ci...

  5. Design and Prototyping of Micro Centrifugal Compressor

    Institute of Scientific and Technical Information of China (English)

    Shimpei Mizuki; Gaku Minorikawa; Toshiyuki Hirano; Yuichiro Asaga; Naoki Yamaguchi; Yutaka Ohta; Eisuke Outa

    2003-01-01

    In order to establish the design methodology of ultra micro centrifugal compressor, which is the most important component of ultra micro gas turbine unit, a 10 times of the final target size model was designed, prototyped and tested. The problems to be solved for downsizing were examined and 2-dimensional impeller was chosen as the first model due to its productivity. The conventional 1D prediction method, CFD and the inverse design were attempted. The prototyped compressor was driven by using a turbocharger and the performance characteristics were measured.

  6. Impeller blade design method for centrifugal compressors

    Science.gov (United States)

    Jansen, W.; Kirschner, A. M.

    1974-01-01

    The design of a centrifugal impeller with blades that are aerodynamically efficient, easy to manufacture, and mechanically sound is discussed. The blade design method described here satisfies the first two criteria and with a judicious choice of certain variables will also satisfy stress considerations. The blade shape is generated by specifying surface velocity distributions and consists of straight-line elements that connect points at hub and shroud. The method may be used to design radially elemented and backward-swept blades. The background, a brief account of the theory, and a sample design are described.

  7. Theory and experiments on centrifuge cratering

    Science.gov (United States)

    Schmidt, R. M.; Holsapple, K. A.

    1980-01-01

    Centrifuge experimental techniques provide possibilities for laboratory simulation of ground motion and cratering effects due to explosive loadings. The results of a similarity analysis for the thermomechanical response of a continuum show that increased gravity is a necessary condition for subscale testing when identical materials for both model and prototype are being used. The general similarity requirements for this type of subscale testing are examined both theoretically and experimentally. The similarity analysis is used to derive the necessary and sufficient requirements due to the general balance and jump equations and gives relations among all the scale factors for size, density, stress, body forces, internal energy, heat supply, heat conduction, heat of detonation, and time. Additional constraints due to specific choices of material constitutive equations are evaluated separately. The class of constitutive equations that add no further requirements is identified. For this class of materials, direct simulation of large-scale cratering events at small scale on the centrifuge is possible and independent of the actual constitutive equations. For a rate-independent soil it is shown that a small experiment at gravity g and energy E is similar to a large event at 1 G but with energy equal to g3E. Consequently, experiments at 500 G with 8 grams of explosives can be used to simulate a kiloton in the field. A series of centrifuge experiments was performed to validate the derived similarity requirements and to determine the practicality of applying the technique to dry granular soils having little or no cohesion. Ten shots using Ottawa sand at various gravities confirmed reproducibility of results in the centrifuge environment, provided information on particle size effects, and demonstrated the applicability of the derived similitude requirements. These experiments used 0.5-4 grams of pentaerythritol-tetranitrate (PETN) and 1.7 grams of lead-azide explosives. They

  8. Illusory movement of stationary stimuli in the visual periphery: evidence for a strong centrifugal prior in motion processing.

    Science.gov (United States)

    Zhang, Ruyuan; Kwon, Oh-Sang; Tadin, Duje

    2013-03-01

    Visual input is remarkably diverse. Certain sensory inputs are more probable than others, mirroring statistical regularities of the visual environment. The visual system exploits many of these regularities, resulting, on average, in better inferences about visual stimuli. However, by incorporating prior knowledge into perceptual decisions, visual processing can also result in perceptions that do not match sensory inputs. Such perceptual biases can often reveal unique insights into underlying mechanisms and computations. For example, a prior assumption that objects move slowly can explain a wide range of motion phenomena. The prior on slow speed is usually rationalized by its match with visual input, which typically includes stationary or slow moving objects. However, this only holds for foveal and parafoveal stimulation. The visual periphery tends to be exposed to faster motions, which are biased toward centrifugal directions. Thus, if prior assumptions derive from experience, peripheral motion processing should be biased toward centrifugal speeds. Here, in experiments with human participants, we support this hypothesis and report a novel visual illusion where stationary objects in the visual periphery are perceived as moving centrifugally, while objects moving as fast as 7°/s toward fovea are perceived as stationary. These behavioral results were quantitatively explained by a Bayesian observer that has a strong centrifugal prior. This prior is consistent with both the prevalence of centrifugal motions in the visual periphery and a centrifugal bias of direction tuning in cortical area MT, supporting the notion that visual processing mirrors its input statistics.

  9. Different Ways to On-Line Hyphenate Centrifugal Partition Chromatography and Mass Spectrometry: Application to Prenylated Xanthones from Garcinia mangostana.

    Science.gov (United States)

    Destandau, Emilie; Michel, Thomas; Toribio, Alix; Elfakir, Claire

    2015-11-01

    Centrifugal partition chromatography is a liquid-liquid separation method well adapted for the fractionation or purification of natural compounds from plant extracts. However, following the preparative isolation, the fractions collected must be analysed by high-performance thin-layer chromatography or high-performance liquid chromatography to evaluate their composition and/or their purity. These additional steps are time-consuming and increase the risk of compound degradation. In order to get an instantaneous analysis of fraction content with structural information on the phytochemicals eluted, it is possible to hyphenate on-line centrifugal partition chromatography with mass spectrometry. Depending on the complexity of the extract, two different kinds of centrifugal partition chromatography-mass spectrometry coupling can be performed: centrifugal partition chromatography-mass spectrometry or centrifugal partition chromatography-high-performance liquid chromatography-mass spectrometry coupling. In the first case, one part of the centrifugal partition chromatography effluent is directly introduced in the mass spectrometry ionisation source to identify the eluted compounds, while in the second case, it is directed to a high-performance liquid chromatography-mass spectrometry system where compounds are first separated thanks to high-performance liquid chromatography and then identified using mass spectrometry.

  10. Different Ways to On-Line Hyphenate Centrifugal Partition Chromatography and Mass Spectrometry: Application to Prenylated Xanthones from Garcinia mangostana.

    Science.gov (United States)

    Destandau, Emilie; Michel, Thomas; Toribio, Alix; Elfakir, Claire

    2015-11-01

    Centrifugal partition chromatography is a liquid-liquid separation method well adapted for the fractionation or purification of natural compounds from plant extracts. However, following the preparative isolation, the fractions collected must be analysed by high-performance thin-layer chromatography or high-performance liquid chromatography to evaluate their composition and/or their purity. These additional steps are time-consuming and increase the risk of compound degradation. In order to get an instantaneous analysis of fraction content with structural information on the phytochemicals eluted, it is possible to hyphenate on-line centrifugal partition chromatography with mass spectrometry. Depending on the complexity of the extract, two different kinds of centrifugal partition chromatography-mass spectrometry coupling can be performed: centrifugal partition chromatography-mass spectrometry or centrifugal partition chromatography-high-performance liquid chromatography-mass spectrometry coupling. In the first case, one part of the centrifugal partition chromatography effluent is directly introduced in the mass spectrometry ionisation source to identify the eluted compounds, while in the second case, it is directed to a high-performance liquid chromatography-mass spectrometry system where compounds are first separated thanks to high-performance liquid chromatography and then identified using mass spectrometry. PMID:25615274

  11. Clinical evaluation of the centrifugal pump in open heart surgery: a comparative study of different pumps.

    Science.gov (United States)

    Takarabe, K; Yoshikai, M; Murayama, J; Hamada, M; Ito, T

    1997-07-01

    The centrifugal pump is now widely used in open heart surgery for its clinical benefits related to the blood elements and the coagulation system. The purpose of this study was to compare the clinical performances of and the outcomes offered by 4 types of centrifugal pumps. For each pump, we investigated the effects on the blood elements, coagulation system, complements, and immunoglobulins during open heart surgery. Four types of centrifugal pumps were used: the HPM-15 (Nikkiso Co.), the Capiox (Terumo Co.), the Lifestream (St. Jude Medical Co.), and the BP-80 (Medtronic, BioMedicus Co.). The platelet count, lactate dehydrogenase (LDH), antithrombin III (AT III), thrombin-antithrombin complex (TAT), complements (C3, C4, and CH50), and immunoglobulins (IgG, IgA, and IgM) were measured before and after cardiopulmonary bypass (CPB). The platelet count was decreased more significantly by the HPM-15 than by any of the other pumps. The other parameters showed no difference among the 4 pumps. In clinical use, each of the 4 types of centrifugal pumps was safe.

  12. Centrifugally Stimulated Exospheric Ion Escape at Mercury

    Science.gov (United States)

    Delcourt, Dominique; Seki, K.; Terada, N.; Moore, Thomas E.

    2012-01-01

    We investigate the transport of ions in the low-altitude magnetosphere magnetosphere of Mercury. We show that, because of small spatial scales, the centrifugal effect due to curvature of the E B drift paths can lead to significant particle energization in the parallel direction. We demonstrate that because of this effect, ions with initial speed smaller than the escape speed such as those produced via thermal desorption can overcome gravity and escape into the magnetosphere. The escape route of this low-energy exosphere originating material is largely controlled by the magnetospheric convection rate. This escape route spreads over a narrower range of altitudes when the convection rate increases. Bulk transport of low-energy planetary material thus occurs within a limited region of space once moderate magnetospheric convection is established. These results suggest that, via release of material otherwise gravitationally trapped, the E B related centrifugal acceleration is an important mechanism for the net supply of plasma to the magnetosphere of Mercury.

  13. Postcardiotomy centrifugal assist: a single surgeon's experience.

    Science.gov (United States)

    Curtis, Jack J; McKenney-Knox, Charlotte A; Wagner-Mann, Colette C

    2002-11-01

    Because of the infrequent application of cardiac assist devices for postcardiotomy heart failure, most published reports include the results of learning curves from multiple surgeons. Between October 1986 and June 2001, a single surgeon used 35 Sarns Centrifugal Pumps as ventricular assist devices in 21 patients with severe hemodynamic compromise after open heart surgery (0.88% incidence). Patients' ages ranged from 39 to 77 (mean, 59.6 years). Three patients required right ventricular assist devices, 4 left ventricular assist devices, and 14 had biventricular assist devices. For all, the indication for application was inability to wean from cardiopulmonary bypass despite multiple inotropes and intraaortic balloon pumping. All were expected to be intraoperative deaths without further mechanical assistance. Patients were assisted from 2 to 434 h (median, 48 h). Fifteen patients (71.4%) were weaned from device(s), and 11 patients (52.4%) were hospital survivors. Actuarial survival in those dismissed from the hospital was 78% at 5 years and 39% at 10 years. Patients facing certain demise after cardiac surgery can be salvaged with temporary centrifugal mechanical assist. Results are competitive with that achieved with more sophisticated devices. Hospital survivors enjoy reasonable longevity.

  14. PARTICLE DISTRIBUTION IN CENTRIFUGAL ACCELERATING FIELDS

    Institute of Scientific and Technical Information of China (English)

    Yu Sirong; Zhang Xinping; He Zhenming; Liu Yaohui

    2003-01-01

    Based on continuum theory and moving law of particles, a model is presented to obtain gradient distribution of particles in centrifugal accelerating field, by which the particle distribution in gradient composite material can be predicted. The simulation shows with increases in rotating time, four regions gradually appear from the internal periphery to the external one, they are free region, transition region, steady region and surface reinforced region,and the latest three regions are defined as a rich region. Finally, the steady region disappears, and the rich region only includes transition region and surface reinforced region. The influences of centrifugal acceleration coefficient G,primary volume fraction (0,pouring temperature (p and density difference between the particle and the metal matrix on particles gradient distribution are studied in detail. The results of the theoretical analysis agree with experiment ones. Both of analysis and experiment results indicate that with the increase in G and (p, the particle distribution becomes more centralized and the consistence of particle in the surface periphery becomes larger.

  15. Some aversive characteristics of centrifugally generated gravity.

    Science.gov (United States)

    Altman, F.

    1973-01-01

    The effective weight of rats was manipulated by centrifugation. Two effective weight levels were obtained. In three escape avoidance conditions a lever press produced a change from a base level of 2.1 g to a response level of 1.1 g. In a punishment condition a response produced a change from a 1.1 g level to a 2.1 g level and in an extinction condition responses had no effect on the 2.1 g effective weight level present. All changes took 30 sec and were maintained for an additional 10 sec before a return to base level was initiated. When responses occurred closer together than the 40 sec, they delayed the return to base level by 40 sec. This 40 sec interval is referred to as response-contingent-time. The response rate and amount of response-contingent-time served as the data. The results confirmed previous data that centrifugation is aversive. The results are interpreted as indicating that the aversiveness is attributable to the increase in effective weight, and that rats can discriminate the different angular velocity-radius of rotation combinations used.

  16. Concrete Cleaning, Inc. centrifugal shot blaster: Baseline report; Summary

    International Nuclear Information System (INIS)

    The centrifugal shot blaster is an electronically operated shot-blast machine that removes layer of concrete of varying depths. Hardened steel shot propelled at a high rate of speed abrades the surface of the concrete. The depth of material removed is determined by the rate of speed the machine is traveling and the volume of shot being fired into the blast chamber. The steel shot is reused until it is pulverized to dust, which is deposited in the waste container with the concrete being removed. Debris is continually vacuumed by a large dust collection system attached to the shot blaster. The safety and health evaluation during the human factors assessment focused on two main areas: noise and dust

  17. A multiple disk centrifugal pump as a blood flow device.

    Science.gov (United States)

    Miller, G E; Etter, B D; Dorsi, J M

    1990-02-01

    A multiple disk, shear force, valveless centrifugal pump was studied to determine its suitability as a blood flow device. A pulsatile version of the Tesla viscous flow turbine was designed by modifying the original steady flow pump concept to produce physiological pressures and flows with the aid of controlling circuitry. Pressures and flows from this pump were compared to a Harvard Apparatus pulsatile piston pump. Both pumps were connected to an artificial circulatory system. Frequency and systolic duration were varied over a range of physiological conditions for both pumps. The results indicated that the Tesla pump, operating in a pulsatile mode, is capable of producing physiologic pressures and flows similar to the Harvard pump and other pulsatile blood pumps. PMID:2312140

  18. Numerical study of a high-speed miniature centrifugal compressor

    Science.gov (United States)

    Li, Xiaoyi

    A miniature centrifugal compressor is a key component of reverse Brayton cycle cryogenic cooling system. The system is commonly used to generate a low cryogenic temperature environment for electronics to increase their efficiency, or generate, store and transport cryogenic liquids, such as liquid hydrogen and oxygen, where space limit is also an issue. Because of space limitation, the compressor is composed of a radial IGV, a radial impeller and an axial-direction diffuser (which reduces the radial size because of smaller diameter). As a result of reduction in size, rotating speed of the impeller is as high as 313,000 rpm, and Helium is used as the working fluid, in order to obtain the required static pressure ratio/rise. Two main characteristics of the compressor---miniature and high-speed, make it distinct from conventional compressors. Higher compressor efficiency is required to obtain a higher COP (coefficient of performance) system. Even though miniature centrifugal compressors start to draw researchers' attention in recent years, understanding of the performance and loss mechanism is still lacking. Since current experimental techniques are not advanced enough to capture details of flow at miniature scale, numerical methods dominate miniature turbomachinery study. This work numerically studied a high speed miniature centrifugal compressor with commercial CFD code. The overall performance of the compressor was predicted with consideration of interaction between blade rows by using sliding mesh model. The law of similarity of turbomachinery was validated for small scale machines. It was found that the specific ratio effect needs to be considered when similarity law is applied. But Reynolds number effect can be neglected. The loss mechanism of each component was analyzed. Loss due to turning bend was significant in each component. Tip leakage loss of small scale turbomachines has more impact on the impeller performance than that of large scale ones. Because the

  19. A specter of coexistence: Is centrifugal community organization haunted by the ghost of competition?

    Science.gov (United States)

    Wasserberg, G.; Kotler, B.P.; Morris, D.W.; Abramsky, Z.

    2006-01-01

    In a centrifugally organized community species prefer the same habitat (called "core") but differ in their secondary habitat preferences. The first model of centrifugal community organization (CCO) predicted that optimally foraging, symmetrically competing species would share use of the core habitat at all density combinations. But one might also assume that the competition in the core habitat is asymmetrical, that is, that one of the species (the dominant) has a behavioral advantage therein. In this study, we asked how should habitat use evolve in a centrifugally organized community if its species compete asymmetrically in the core habitat? To address this question we developed an "isoleg model". The model predicts that in a centrifugally organized community, asymmetric competition promotes the use of the core habitat exclusively by the dominant species at most points in the state space. The separation of the core habitat use by the species ("the ghost of competition past") may be either complete or partial ("partial ghost"), and behavior at the stable competitive equilibrium between the species could determine whether coexistence should occur at the "complete-" or the "partial ghost" regions. This version of CCO should be a common feature of competitive systems.

  20. EXPERIMENTAL INVESTIGATION OF ROTATING STALL FOR A LOW-SPEED CENTRIFUGAL COMPRESSOR

    Institute of Scientific and Technical Information of China (English)

    ZHU Xiaocheng; GUO Qiang; DU Zhaohui; CHEN Hua; ZHAO Yan

    2008-01-01

    Unsteady flows and rotating stall of a low-speed centrifugal compressor are investigated by measuring vaneless diffuser wall static pressure fluctuation and internal flow fields at different small flow fluxes. During the experiment, firstly the real time static pressure fluctuations on the vaneless diffuser shroud at different circumferential and radial position were acquired by high-frequency dynamic pressure transducers. Discrete Fourier transformation analysis and cross-correlation analysis were applied to the experimental results to ascertain the rotating stall beginning operation conditions and stall cells numbers and rotating speed. Secondly, the vaneless diffuser inlet flow angle distribution along diffuser width direction was acquired by single hotwire, which was compared with SENOO's analysis results. At last, the internal flow fields of the centrifugal compressor were investigated with a particle image velocimetry (PIV) system at different small flow fluxes. The flow field development of vaneless diffuser and blade flow passage are given at rotating stall conditions. The experiments enrich the understanding of rotating stall flow phenomenon of the low-speed centrifugal compressor and provide full experiment data for designing high performance centrifugal compressor.

  1. Transition to centrifuging granular flow in rotating tumblers: a modified Froude number

    International Nuclear Information System (INIS)

    Centrifuging of granular material in a partially filled rotating circular tumbler occurs when particles are flung outward to form a ring of particles at the periphery of the tumbler rotating as a solid body. The critical rotation speed for centrifuging was studied experimentally in a quasi-two-dimensional tumbler as a function of particle diameter, tumbler fill fraction and interstitial fluid. A qualitative numerical study using the discrete element method was also conducted to obtain a better understanding of the impact of friction on the transition. Experimental results show that the critical rotational speed for dry systems is not affected by the particle diameter unless the fill fraction is above 75%, where endwall friction begins to play a significant role. The critical speed is proportional to (1-φ)(-1/4), where φ represents the tumbler fill fraction. The angle of repose, which represents inter-particle friction, also affects the transition to centrifuging. Finally, the interstitial fluid, or rather the density difference between the particles and the interstitial fluid, affects the measured critical speed. Correction terms for the critical rotational speed are proposed to more accurately characterize the transition to centrifuging for granular flow in rotating tumblers, resulting in a modified Froude number.

  2. Experimental testing of centrifugal pump: small and medium sized enterprise product

    Science.gov (United States)

    Ismail, R.; Paddiyatu, F.; Khafidh, M.; Nugroho, S.; Sugiyanto, S.; Jamari, J.

    2014-06-01

    This paper reports the experimental testing for centrifugal pump for fisherman ship, manufactured by small and medium sized enterprises in Central Java Province, Indonesia. The research covers material analysis, component observation, endurance and vibration test. Six centrifugal pumps are tested and three main pump components are discussed: shaft, bearings and seals. The results show that the material of the shaft is predicted to support and transmit the load from the engine to impeller. The problem found in the tolerance and geometry accuracy of the shaft which causes difficulties during assembling process, excessive wear and leakage during testing. From the endurance and vibration test, the ball bearings fail and lock the shaft due to the fatigue on the rolling elements and raceways. The oil seal and water seal also fail in maintaining the oil and water in the chamber and induce the unlubricated system for the ball bearings. Some suggestions are delivered to improve the product quality of the centrifugal pump. A good quality of the centrifugal pump for fishermen ship and long life span is expected to be produced by local SMEs to win the free trade competition in the Indonesian market.

  3. High Efficiency Centrifugal Compressor for Rotorcraft Applications

    Science.gov (United States)

    Medic, Gorazd; Sharma, Om P.; Jongwook, Joo; Hardin, Larry W.; McCormick, Duane C.; Cousins, William T.; Lurie, Elizabeth A.; Shabbir, Aamir; Holley, Brian M.; Van Slooten, Paul R.

    2014-01-01

    The report "High Efficiency Centrifugal Compressor for Rotorcraft Applications" documents the work conducted at UTRC under the NRA Contract NNC08CB03C, with cost share 2/3 NASA, and 1/3 UTRC, that has been extended to 4.5 years. The purpose of this effort was to identify key technical barriers to advancing the state-of-the-art of small centrifugal compressor stages; to delineate the measurements required to provide insight into the flow physics of the technical barriers; to design, fabricate, install, and test a state-of-the-art research compressor that is representative of the rear stage of an axial-centrifugal aero-engine; and to acquire detailed aerodynamic performance and research quality data to clarify flow physics and to establish detailed data sets for future application. The design activity centered on meeting the goal set outlined in the NASA solicitation-the design target was to increase efficiency at higher work factor, while also reducing the maximum diameter of the stage. To fit within the existing Small Engine Components Test Facility at NASA Glenn Research Center (GRC) and to facilitate component re-use, certain key design parameters were fixed by UTRC, including impeller tip diameter, impeller rotational speed, and impeller inlet hub and shroud radii. This report describes the design effort of the High Efficiency Centrifugal Compressor stage (HECC) and delineation of measurements, fabrication of the compressor, and the initial tests that were performed. A new High-Efficiency Centrifugal Compressor stage with a very challenging reduction in radius ratio was successfully designed, fabricated and installed at GRC. The testing was successful, with no mechanical problems and the running clearances were achieved without impeller rubs. Overall, measured pressure ratio of 4.68, work factor of 0.81, and at design exit corrected flow rate of 3 lbm/s met the target requirements. Polytropic efficiency of 85.5 percent and stall margin of 7.5 percent were

  4. Separative power of an optimised concurrent gas centrifuge

    CERN Document Server

    Bogovalov, S V

    2015-01-01

    The problem of separation of uranium isotopes in a concurrent gas centrifuge is solved analytically. Separative power of the optimized concurrent gas centrifuges equals to $\\delta U=12.7(V/700~{\\rm m/s})^2 (300 ~{\\rm K}/T)L, ~{\\rm kg ~SWU/yr}$, where $L$ and $V$ are the length and linear velocity of the rotor of the gas centrifuge, $T$ is the temperature. This formula well agrees with an empirical separative power of counter current gas centrifuges. The optimal value of the separative power is not unique on the plane $(p_w,v_z)$, where $p_w$ is pressure at the wall of the rotor and $v_z$ is axial velocity of the gas. This value is constant on a line defined by the equation $p_wv_z=constant$. Equations defining the mass flux and the electric power necessary to support the rotation of the gas centrifuge are obtained.

  5. Current status of the gyro centrifugal blood pump--development of the permanently implantable centrifugal blood pump as a biventricular assist device (NEDO project).

    Science.gov (United States)

    Nosé, Yukihiko; Furukawa, Kojiro

    2004-10-01

    The New Energy and Industrial Technology Development Organization (NEDO) project was started in 1995. The goal is the development of a multipurpose, totally implantable biventricular assist device (BVAD) that can be used for any patient who suffers from severe heart failure. Our C1E3 (two-week pump) centrifugal pump, called the Gyro pump, has three design characteristics: a magnetic coupling and double pivot bearing system, an eccentric inlet port, and secondary vanes on the bottom of the impeller. The pump was miniaturized. The C1E3 evolved into the NEDO PI-601, a totally implantable centrifugal pump for BVAD. The current NEDO PI-710 pump (five-year pump) system includes a centrifugal pump with pivot bearings, a hydraulically-levitated impeller, an rpm-controlled miniaturized actuator (all-in-one actuator plus controller), an emergency clamp on the left outflow, and a Frank-Starling-type flow control. The final mass production model is now finalized, and the final animal study and two-year endurance studies are ongoing.

  6. Recent advances in centrifugal contactors design

    International Nuclear Information System (INIS)

    Advances in thedesign of the Argonne centrifugal contactor for solvent extaction are being realized as these contactors are built, tested, and used to implement the TRUEX process for the cleanup of nuclear waste liquids. These advances include (1) using off-the-shelf, face-mounted motors, (2) modifying the contractor so that relatively volatile solvents can be used, (3) adding a high-level liquid detector that can be used to alert the plant operator of process upsets, (4) providing secondary feed ports, (5) optimizing support frame design, (6) maintaining a linear design with external interstage lines so the stages can be allocated as needed for extraction, scrub, strip, and solvent cleanup operations, and (7) developing features that facilitate contractor operation in remote facilities. 11 refs., 8 figs

  7. Centrifugal acceleration of plasma in pulsar magnetosphere

    Indian Academy of Sciences (India)

    R T Gangadhara; V Krishna

    2003-12-01

    We present a relativistic model for the centrifugal acceleration of plasma bunches and the coherent radio emission in pulsar magnetosphere. We find that rotation broadens the width of leading component compared to the width of trailing component. We explain this difference in the component widths using the nested cone emission geometry. We estimate the effect of pulsar spin on the Stokes parameters, and find that the inclination between the rotation and magnetic axes can introduce an asymmetry in the circular polarization of the conal components. We analyse the single pulse polarization data of PSR B0329+54 at 606 MHz, and find that in its conal components, one sense of circular polarization dominates in the leading component while the other sense dominates in the trailing component. Our simulation shows that changing the sign of the impact parameter changes the sense of circular polarization as well as the swing of polarization angle.

  8. Stability of centrifugal pump characteristic curve

    OpenAIRE

    Chmatil, Ľuboš

    2011-01-01

    Předložená diplomová práce obsahuje teoretický rozbor charakteristik odstředíveho čerpadla, podmínky stability Y(Q) charakteristiky, výpočet charakteristiky ßč(ns), úpravy vedúce k stabilizaci spirálního telesa a oběžného kola, návrh spirály, obežného kola a následný výpočet v programe Fluent. This master's thesis includes theoretical analysis of characteristics of a centrifugal pump, conditions of stability of Y(Q) characteristic, calculation of characteristics ßč(ns), modifications leadi...

  9. Rotordynamic forces on centrifugal pump impellers

    Science.gov (United States)

    Franz, R.; Arndt, N.; Caughey, T. K.; Brennen, C. E.; Acosta, A. J.

    1987-01-01

    The asymmetric flow around an impeller in a volute exerts a force upon the impeller. To study the rotordynamic force on an impeller which is vibrating around its machine axis of rotation, the impeller, mounted on a dynamometer, is made to whirl in a circular orbit within the volute. The measured force is expressed as the sum of a steady radial force and an unsteady force due to the eccentric motion of the impeller. These forces were measured in separate tests on a centrifugal pump with radically increased shroud clearance, a two-dimensional impeller, and an impeller with an inducer, the impeller of the HPOTP (High Pressure Oxygen Turbopump) of the SSME (Space Shuttle Main Engine). In each case, a destabilizing force was observed over a region of positive whirl.

  10. Carnosol purification. Scaling-up centrifugal partition chromatography separations.

    Science.gov (United States)

    Bouju, Elodie; Berthod, Alain; Faure, Karine

    2016-09-30

    This paper illustrates the application of a recently proposed protocol allowing the scale-up prediction on hydrostatic countercurrent chromatography columns (centrifugal partition chromatographs or CPC). A commercial extract of rosemary (Rosmarinus officinalis L.) was used as the starting material containing 0.48% of carnosol, an active pharmaceutical ingredient with great potential. After a rapid method development on a small-scale 35-mL CPC instrument that allowed for the determination of the solvent system and maximum sample concentration and volume, the purification was transferred on two larger instruments using the "free space between peaks" method. The method takes into account the technical limitations of the larger instruments, such as pressure and/or maximum centrifugal field, and allows, by simply running an analytical-sized injection on the large scale rotor, to give an accurate prediction of the maximum sample load and best throughput. The 0.27g of rosemary extract maximum load on a 35-mL CPC was transferred as a 1.9g load on a 254-mL medium size CPC and 9g load on a 812-mL CPC. The maximum process efficiency of 3.1mg of carnosol per hour obtained on the small 35-mL column was transferred on the 254-mL CPC giving 8.3mg/h and, on the larger 812-mL column 49.4mg of carnosol could be obtained per hour. If the scaling-up in CPC instruments is not directly homothetic, it can be highly predictable through a few simple experiments. PMID:27590084

  11. Carnosol purification. Scaling-up centrifugal partition chromatography separations.

    Science.gov (United States)

    Bouju, Elodie; Berthod, Alain; Faure, Karine

    2016-09-30

    This paper illustrates the application of a recently proposed protocol allowing the scale-up prediction on hydrostatic countercurrent chromatography columns (centrifugal partition chromatographs or CPC). A commercial extract of rosemary (Rosmarinus officinalis L.) was used as the starting material containing 0.48% of carnosol, an active pharmaceutical ingredient with great potential. After a rapid method development on a small-scale 35-mL CPC instrument that allowed for the determination of the solvent system and maximum sample concentration and volume, the purification was transferred on two larger instruments using the "free space between peaks" method. The method takes into account the technical limitations of the larger instruments, such as pressure and/or maximum centrifugal field, and allows, by simply running an analytical-sized injection on the large scale rotor, to give an accurate prediction of the maximum sample load and best throughput. The 0.27g of rosemary extract maximum load on a 35-mL CPC was transferred as a 1.9g load on a 254-mL medium size CPC and 9g load on a 812-mL CPC. The maximum process efficiency of 3.1mg of carnosol per hour obtained on the small 35-mL column was transferred on the 254-mL CPC giving 8.3mg/h and, on the larger 812-mL column 49.4mg of carnosol could be obtained per hour. If the scaling-up in CPC instruments is not directly homothetic, it can be highly predictable through a few simple experiments.

  12. A Novel Fabrication Method for Functionally Graded Materials under Centrifugal Force: The Centrifugal Mixed-Powder Method

    Directory of Open Access Journals (Sweden)

    Eri Miura-Fujiwara

    2009-12-01

    Full Text Available One of the fabrication methods for functionally graded materials (FGMs is a centrifugal solid-particle method, which is an application of the centrifugal casting technique. However, it is the difficult to fabricate FGMs containing nano-particles by the centrifugal solid-particle method. Recently, we proposed a novel fabrication method, which we have named the centrifugal mixed-powder method, by which we can obtain FGMs containing nano-particles. Using this processing method, Cu-based FGMs containing SiC particles and Al-based FGMs containing TiO2 nano-particles on their surfaces have been fabricated. In this article, the microstructure and mechanical property of Cu/SiC and Al/TiO2 FGMs, fabricated by the centrifugal mixed-powder method are reviewed.

  13. Analysis of centrifugal convection in rotating pipes

    Science.gov (United States)

    Shtern, Vladimir; Zimin, Valery; Hussain, Fazle

    2001-08-01

    New exact solutions, obtained for centrifugal convection of a compressible fluid in pipes and annular pipes, explain axially elongated counterflow and energy separation—poorly understood phenomena occurring in vortex devices, e.g., hydrocyclones and Ranque tubes. Centrifugal acceleration (which can be up to 106 times gravity in practical vortex tubes), combined with an axial gradient of temperature (even small), induces an intense flow from the cold end to the hot end along the pipe wall and a backflow near the axis. To account for large density variations in vortex devices, we use the axial temperature gradient as a small parameter instead of the Boussinesq approximation. For weak pipe rotation, the swirl is of solid-body type and solutions are compact: vz/vza=1-4y2+3y4 and (T-Tw)/(Ta-Tw)=(1-y2)3; where y=r/rw, the subscripts w and a denote values of axial velocity vz, temperature T, and radial distance r, at the wall and on the axis. The axial gradient of pressure, being proportional to 3y2-1, has opposite directions near the wall, y=1, and near the axis, y=0; this explains the counterflow. With increasing pipe rotation, the flow starts to converge to the axis. This causes important new effects: (i) the density and swirl velocity maxima occur away from the wall (vortex core formation), (ii) the temperature near the axis becomes lower than near the wall (the Ranque effect), (iii) the axial gradient of temperature drops from the wall to the axis, and (iv) the total axial heat flux (Nu) reaches its maximum Numax≈4000 and then decreases as swirl increases. These features can be exploited for the development of a micro-heat-exchanger, e.g., for cooling computer chips.

  14. A straight path centrifugal blood pump concept in the Capiox centrifugal pump.

    Science.gov (United States)

    Kijima, T; Oshiyama, H; Horiuchi, K; Nogawa, A; Hamasaki, H; Amano, N; Nojiri, C; Fukasawa, H; Akutsu, T

    1993-07-01

    This article describes comparative studies of a newly developed "straight path" centrifugal pump (Capiox centrifugal pump) targeted for open-heart surgery and circulatory support. A unique straight path design of the rotor was very effective in reducing the pump's rotational speed and prime volume. This pump was evaluated for hydraulics, hemolysis, depriming characteristics, cavitation, and heat generation. Two commercially available centrifugal pumps, the Biomedicus cone-type pump and the Sarns 3M impeller-type pump, were used as controls. The new pump required the lowest pump speed to produce the same flow rates under the same pressure loads and demonstrated the lowest hemolysis and the lowest temperature rise with the outlet clamped. The air volume required to deprime the new pump was one-third to one-half that for the other pumps, and no sign of cavitation was observed even if a small amount of air was introduced to the pump inlet under a negative pressure of 200 mm Hg.

  15. Trajectory and terminal distribution of single centrifugal axons from olfactory cortical areas in the rat olfactory bulb.

    Science.gov (United States)

    Matsutani, S

    2010-08-11

    The olfactory bulb receives a large number of centrifugal fibers whose functions remain unclear. To gain insight into the function of the bulbar centrifugal system, the morphology of individual centrifugal axons from olfactory cortical areas was examined in detail. An anterograde tracer, Phaseolus vulgaris leucoagglutinin, was injected into rat olfactory cortical areas, including the pars lateralis of the anterior olfactory nucleus (lAON) and the anterior part of the piriform cortex (aPC). Reconstruction from serial sections revealed that the extrabulbar segments of centrifugal axons from the lAON and those from the aPC had distinct trajectories: the former tended to innervate the pars externa of the AON before entering the olfactory bulb, while the latter had extrabulbar collaterals that extended to a variety of targets. In contrast to the extrabulbar segments, no clear differences were found between the intrabulbar segments of axons from the lAON and from the aPC. The intrabulbar segments of centrifugal axons were mainly found in the granule cell layer but a few axons extended into the external plexiform and glomerular layer. Approximately 40% of centrifugal axons innervated both the medial and lateral aspects of the olfactory bulb. The number of boutons found on single intrabulbar segments was typically less than 1000. Boutons tended to aggregate and form complex terminal tufts with short axonal branches. Terminal tufts, no more than 10 in single axons from ipsilateral cortical areas, were localized to the granule cell layer with varying intervals; some tufts formed patchy clusters and others were scattered over areas that extended for a few millimeters. The patchy, widespread distribution of terminals suggests that the centrifugal axons are able to couple the activity of specific subsets of bulbar neurons even when the subsets are spatially separated.

  16. Tropic responses of Phycomyces sporangiophores to gravitational and centrifugal stimuli.

    Science.gov (United States)

    DENNISON, D S

    1961-09-01

    A low-speed centrifuge was used to study the tropic responses of Phycomyces sporangiophores in darkness to the stimulus of combined gravitational and centrifugal forces. If this stimulus is constant the response is a relatively slow tropic reaction, which persists for up to 12 hours. The response is accelerated by increasing the magnitude of the gravitational-centrifugal force. A wholly different tropic response, the transient response, is elicited by an abrupt change in the gravitational-centrifugal stimulus. The transient response has a duration of only about 6 min. but is characterized by a high bending speed (about 5 degrees /min.). An analysis of the distribution of the transient response along the growing zone shows that the active phase of the response has a distribution similar to that of the light sensitivity for the light-growth and phototropic responses. Experiments in which sporangiophores are centrifuged in an inert dense fluid indicate that the sensory mechanism of the transient response is closely related to the physical deformation of the growing zone caused by the action of the gravitational-centrifugal force on the sporangiophore as a whole. However, the response to a steady gravitational-centrifugal force is most likely not connected with this deformation, but is probably triggered by the shifting of regions or particles of differing density relative to one another inside the cell. PMID:13721903

  17. Purification of Sardinella sp., Oil: Centrifugation and Bentonite Adsorbent

    Directory of Open Access Journals (Sweden)

    S.H. Suseno

    2014-01-01

    Full Text Available Centrifugation and purification using adsorbents is one example of a fish oil refining techniques applied to reduce impurities of fish oil. The study aimed to determine the sardine oil quality before treatment, to determine yield of fish oil after centrifugation treatment and to determine the influence of centrifugation speed and bentonite concentration on sardine oil quality. Factorial design with two factors was used in this study. Level of free fatty acid and peroxide value before purification was 35.53% and 170 mEq/kg. Yield of fish oil after centrifugation treatment has been ranged from 17.42±3.56 to 76.33±0.21%. The best treatment which could reduce the peroxide value and total oxidation was a treatment with centrifugation speed at 6500 rpm and bentonite concentration at 3%. Peroxide value and total oxidation of its treatment was 25.00±0.00 and 51.43±0.01 mEq/kg. The lowest value of p-anisidine was 1.29±0.05 mEq/kg and its value could be found in a treatment with centrifugation speed at 4500 rpm and bentonite concentration at 5%. The level of free fatty acid after purification process was ranged from 27.35 to 34.69%. Oil clarity tended to increase with the increase of centrifugation speed and adsorbent concentration.

  18. Performance analysis of mini centrifugal pump with splitter blades

    Science.gov (United States)

    Shigemitsu, T.; Fukutomi, J.; Wada, T.; Shinohara, H.

    2013-12-01

    Design method for a mini centrifugal pump is not established because the internal flow condition for these small-sized fluid machines is not clarified and conventional theory is not suitable for small-sized pumps. Then, a semi-open impeller for the mini centrifugal pump with 55mm impeller diameter is adopted in this research to take simplicity and maintenance into consideration. Splitter blades are adopted in this research to improve the performance and internal flow condition of mini centrifugal pump having large blade outlet angle. The performance tests are conducted with these rotors in order to investigate the effect of the splitter blades on the performance and internal flow condition of the mini centrifugal pump. A three dimensional steady numerical flow analysis is conducted to analyze rotor, volute efficiency and loss caused by a vortex. It is clarified from the experimental results that the performance of the mini centrifugal pump is improved by the effect of the splitter blades. Flow condition at outlet of the rotor becomes uniform and back flow regions are suppressed in the case with the splitter blades. Further, the volute efficiency increases and the vortex loss decreases. In the present paper, the performance of the mini centrifugal pump is shown and the flow condition is clarified with the results of the experiment and the numerical flow analysis. Furthermore, the performance analyses of the mini centrifugal pumps with and without the splitter blades are conducted.

  19. Effect of simulated microgravity and centrifugation on nitric oxide synthase activity of osteocyte-like cell line MLO-Y4

    Science.gov (United States)

    Sun, Lian-Wen; Yang, Xiao; Fan, Yu-Bo

    Bone is a highly mechanosensitive tissue, which can adapt functionally to varying levels of mechanical loads throughout a lifetime. Osteocytes are thought to be the most mechanically sensitive bone cell population. In order to understand the mechanism of microgravity-induced bone loss, it's very important to research the behavior of osteocytes under microgravity. In this study, rotary cell culture system was used to simulate microgravity. Nitric oxide synthase (NOS) activity in osteocyte-like cell MLO-Y4 was investigated under simulated microgravity. And the effect of centrifugation on NOS activity in sedentary and rotary culture cell was also investi-gated. The cultured cells were divided into four groups, including sedentary control (CON), sedentary control and centrifugation (CONC), rotary culture (RT), rotary and centrifugation (RTC). In CONC and RTC, NOS activity was determined after centrifugation (1100g 5min). The results showed NOS activity decreased significantly in RT compared with CON. However, this difference disappeared after centrifugation. On the other hand, NOS activity increased significant in RTC compared with RT while there was no difference between CON and CONC. These results indicate the normal centrifugation could counter the effect of simulated micro-gravity on NOS activity. However, it has no effect on the cells cultured under 1G. In general, osteocytes under simulated microgravity are more sensitive to centrifugation than that under 1G.

  20. Model of mass transfer processes in the cascade of centrifugal extractors

    Science.gov (United States)

    Zelenetskaya, E. P.; Goryunov, A. G.; Daneikina, N. V.

    2016-06-01

    The paper describes a mathematical model of mass transfer processes in a cascade of reverse-flow centrifugal extractors. Model of operation of each extractor is given as tightly coupled system of mixing and separating chambers. All model units are represented by systems of differential equations. The article presents the results of testing of the developed model, which confirmed the validity of the assumptions made in the model. The authors assessed the impact of the overflow of dense phase level on the hydrostatic position of phase interface level in the extractor. The research showed that a change in the volume of dense and light phases occurs in each apparatus of a cascade even in the steady mode. Operation of the cascade consisting of 12 series-connected centrifugal extractors was simulated in order to verify the model. Computer simulation results confirm the adequacy of the developed model.

  1. A New Approach to Designing the S-Shaped Annular Duct for Industrial Centrifugal Compressor

    Directory of Open Access Journals (Sweden)

    Ivan Yurko

    2014-01-01

    Full Text Available The authors propose an analytical method for designing the inlet annular duct for an industrial centrifugal compressor using high-order Bezier curves. Using the design of experiments (DOE theory, the three-level full factorial design was developed for determination of influence of the dimensionless geometric parameters on the output criteria. Numerical research was carried out for determination of pressure loss coefficients and velocity swirl angles using the software system ANSYS CFX. Optimal values of the slope for a wide range of geometric parameters, allowing minimizing losses in the duct, have been found. The study has used modern computational fluid dynamics techniques to develop a generalized technique for future development of efficient variable inlet guide vane systems. Recommendations for design of the s-shaped annular duct for industrial centrifugal compressor have been given.

  2. SEQUENTIAL DIAGNOSIS FOR A CENTRIFUGAL PUMP BASED ON FUZZY NEURAL NETWORK

    Institute of Scientific and Technical Information of China (English)

    ZHOU Xiong; WANG Huaqing; CHEN Peng; TANG Yike

    2008-01-01

    A sequential diagnosis method is proposed based on a fuzzy neural network realized by "the partially-linearized neural network (PNN)", by which the fault types of rotating machinery can be precisely and effectively distinguished at an early stage on the basis of the possibilities of symptom parameters. The non-dimensional symptom parameters in time domain are defined for reflecting the features of time signals measured for the fault diagnosis of rotating machinery. The synthetic detection index is also proposed to evaluate the sensitivity of non-dimensional symptom parameters for detecting faults. The practical example of condition diagnosis for detecting and distinguishing fault states of a centrifugal pump system, such as cavitation, impeller eccentricity which often occur in a centrifugal pump system, are shown to verify the efficiency of the method proposed in this paper.

  3. Control of Surge in Centrifugal Compressors by Active Magnetic Bearings Theory and Implementation

    CERN Document Server

    Yoon, Se Young; Allaire, Paul E

    2013-01-01

    Control of Surge in Centrifugal Compressors by Active Magnetic Bearings sets out the fundamentals of integrating the active magnetic bearing (AMB) rotor suspension technology in compressor systems, and describes how this relatively new bearing technology can be employed in the active control of compressor surge. The authors provide a self-contained and comprehensive review of rotordynamics and the fundamentals of the AMB technology. The active stabilization of compressor surge employing AMBs in a machine is fully explored, from the modeling of the instability and the design of feedback controllers, to the implementation and experimental testing of the control algorithms in a specially-constructed, industrial-size centrifugal compression system. The results of these tests demonstrate the great potential of the new surge control method developed in this text. This book will be useful for engineers in industries that involve turbocompressors and magnetic bearings, as well as for researchers and graduate students...

  4. Study on seal improvement and rotor thrust control of centrifugal compressor

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Fluid pressure variations due to process fluctuations or balance drum seal degradation can result in rotor thrust increasing that may jeopardize thrust bearing and compressor's reliability. Also, the leakage flow through balance drum seal can seriously affect the efficiency of compressor. A method that can improve both the efficiency and reliability of centrifugal compressor is presented. The method focused on rotor thrust control and balance drum seal upgrading. The low leakage feature of Dry-Gas-Seal(DGS), high reliability of labyrinth, and the feasibility of upgrading existing structure are taken into account at the same time to design a combined labyrinth-dry gas seal system on the balancing drum. Based on the combined seal system, a Fault Self-Recovering(FSR) system for the fault of rotor shaft displacement is introduced to assure the safety and reliability of centrifugal compressor. The modern Computational Fluid Dynamics(CFD) is used to validate this envision. The numerical result and relevant information indicate that the combined sealing system could improve the efficiency of the centrifugal compressor by about 4%.

  5. Modifying a Commercial Centrifuge to Reduce Electromagnetic Interference and Evaluating Functionality of Ultrasound Equipment

    Science.gov (United States)

    Greening, Gage J.

    2016-01-01

    The Project Management and Engineering Branch (SF4) supports the Human Health and Performance Directorate (HH&P) and is responsible for developing and supporting human systems hardware for the International Space Station (ISS). When a principal investigator's (PI) medical research project on the ISS is accepted, SF4 develops the necessary hardware and software to transport to the ISS. The two projects I primarily worked on were the centrifuge and ultrasound projects. Centrifuge: One concern with spacecraft such as the ISS is electromagnetic interference (EMI) from onboard equipment, typically from radio waves (frequencies of 3 kHz to 300 GHz), which can negatively affect nearby circuitry. Standard commercial centrifuges produce EMI above safety limits, so my task was to help reduce EMI production from this equipment. Two centrifuges were tested: one unmodified as a control and one modified. To reduce EMI below safety limits, one centrifuge was modified to become a Faraday shield, in which significant electrical contact was made between all regions of the centrifuge housing. This included removing non-conductive paint, applying conductive fabric to the lid and foam sealer, adding a 10,000 µF decoupling capacitor across the power supply, and adding copper adhesive-mount gaskets to the housing interior. EMI testing of both centrifuges was performed in the EMI/EMC Control Test and Measurement Facility. EMI for both centrifuges was below safety limits for frequencies between 10 MHz and 15 GHz (pass); however, between 14 kHz and 10 MHz, EMI for the unmodified centrifuge exceeded safety limits (fail) as expected. Alternatively, for the modified centrifuge with the Faraday shield, EMI was below the safely limit of 55 dBµV/m for electromagnetic frequencies between 14 kHz and 10 MHz. This result indicates our modifications were successful. The successful EMI test allowed us to communicate with the vendor what modifications they needed to make to their commercial unit to

  6. Speed and surge control for a lower order centrifugal compressor model

    OpenAIRE

    Gravdahl, Jan T; Olav Egeland

    1998-01-01

    A model of a variable speed centrifugal compression system is presented. The model is based on the work of Greitzer (1976), but the compressor characteristic is developed by modelling the losses in the compressor. For surge control, a close coupled valve is employed. This valve is placed immediately downstream of the compressor, and the pressure drop over the valve is used as the control variable. This makes it possible to manipulate the shape of the equivalent compressor, consisting of compr...

  7. A New Approach to Designing the S-Shaped Annular Duct for Industrial Centrifugal Compressor

    OpenAIRE

    Ivan Yurko; German Bondarenko

    2014-01-01

    The authors propose an analytical method for designing the inlet annular duct for an industrial centrifugal compressor using high-order Bezier curves. Using the design of experiments (DOE) theory, the three-level full factorial design was developed for determination of influence of the dimensionless geometric parameters on the output criteria. Numerical research was carried out for determination of pressure loss coefficients and velocity swirl angles using the software system ANSYS CFX. Optim...

  8. New Measures to Safeguard Gas Centrifuge Enrichment Plants

    Energy Technology Data Exchange (ETDEWEB)

    Whitaker, Jr., James [ORNL; Garner, James R [ORNL; Whitaker, Michael [ORNL; Lockwood, Dunbar [U.S. Department of Energy, NNSA; Gilligan, Kimberly V [ORNL; Younkin, James R [ORNL; Hooper, David A [ORNL; Henkel, James J [ORNL; Krichinsky, Alan M [ORNL

    2011-01-01

    As Gas Centrifuge Enrichment Plants (GCEPs) increase in separative work unit (SWU) capacity, the current International Atomic Energy Agency (IAEA) model safeguards approach needs to be strengthened. New measures to increase the effectiveness of the safeguards approach are being investigated that will be mutually beneficial to the facility operators and the IAEA. One of the key concepts being studied for application at future GCEPs is embracing joint use equipment for process monitoring of load cells at feed and withdrawal (F/W) stations. A mock F/W system was built at Oak Ridge National Laboratory (ORNL) to generate and collect F/W data from an analogous system. The ORNL system has been used to collect data representing several realistic normal process and off-normal (including diversion) scenarios. Emphasis is placed on the novelty of the analysis of data from the sensors as well as the ability to build information out of raw data, which facilitates a more effective and efficient verification process. This paper will provide a progress report on recent accomplishments and next steps.

  9. Oil-free centrifugal hydrogen compression technology demonstration

    Energy Technology Data Exchange (ETDEWEB)

    Heshmat, Hooshang [Mohawk Innovative Technology Inc., Albany, NY (United States)

    2014-05-31

    One of the key elements in realizing a mature market for hydrogen vehicles is the deployment of a safe and efficient hydrogen production and delivery infrastructure on a scale that can compete economically with current fuels. The challenge, however, is that hydrogen, being the lightest and smallest of gases with a lower viscosity and density than natural gas, readily migrates through small spaces and is difficult to compresses efficiently. While efficient and cost effective compression technology is crucial to effective pipeline delivery of hydrogen, the compression methods used currently rely on oil lubricated positive displacement (PD) machines. PD compression technology is very costly, has poor reliability and durability, especially for components subjected to wear (e.g., valves, rider bands and piston rings) and contaminates hydrogen with lubricating fluid. Even so called “oil-free” machines use oil lubricants that migrate into and contaminate the gas path. Due to the poor reliability of PD compressors, current hydrogen producers often install duplicate units in order to maintain on-line times of 98-99%. Such machine redundancy adds substantially to system capital costs. As such, DOE deemed that low capital cost, reliable, efficient and oil-free advanced compressor technologies are needed. MiTi’s solution is a completely oil-free, multi-stage, high-speed, centrifugal compressor designed for flow capacity of 500,000 kg/day with a discharge pressure of 1200 psig. The design employs oil-free compliant foil bearings and seals to allow for very high operating speeds, totally contamination free operation, long life and reliability. This design meets the DOE’s performance targets and achieves an extremely aggressive, specific power metric of 0.48 kW-hr/kg and provides significant improvements in reliability/durability, energy efficiency, sealing and freedom from contamination. The multi-stage compressor system concept has been validated through full scale

  10. Confusion around the tidal force and the centrifugal force

    CERN Document Server

    Matsuda, Takuya; Boffin, Henri M J

    2015-01-01

    We discuss the tidal force, whose notion is sometimes misunderstood in the public domain literature. We discuss the tidal force exerted by a secondary point mass on an extended primary body such as the Earth. The tidal force arises because the gravitational force exerted on the extended body by the secondary mass is not uniform across the primary. In the derivation of the tidal force, the non-uniformity of the gravity is essential, and inertial forces such as the centrifugal force are not needed. Nevertheless, it is often asserted that the tidal force can be explained by the centrifugal force. If we literally take into account the centrifugal force, it would mislead us. We therefore also discuss the proper treatment of the centrifugal force.

  11. Experimental study on cavitation in centrifugal pump impellers

    International Nuclear Information System (INIS)

    Investigations concerning cavitation in centrifugal impellers were carried out in a closed circuit. The value of net positive suction head (NPSH) at different head drops and at breakdown were used to verify the affinity laws

  12. MULTIOBJECT OPTIMIZATION OF A CENTRIFUGAL IMPELLER USING EVOLUTIONARY ALGORITHMS

    Institute of Scientific and Technical Information of China (English)

    Li Jun; Liu Lijun; Feng Zhenping

    2004-01-01

    Application of the multiobjective evolutionary algorithms to the aerodynamic optimization design of a centrifugal impeller is presented. The aerodynamic performance of a centrifugal impeller is evaluated by using the three-dimensional Navier-Stokes solutions. The typical centrifugal impeller is redesigned for maximization of the pressure rise and blade load and minimization of the rotational total pressure loss at the given flow conditions. The B閦ier curves are used to parameterize the three-dimensional impeller blade shape. The present method obtains many reasonable Pareto optimal designs that outperform the original centrifugal impeller. Detailed observation of the certain Pareto optimal design demonstrates the feasibility of the present multiobjective optimization method tool for turbomachinery design.

  13. TECHNOLOGY EVALUATION REPORT: RETECH'S PLASMA CENTRIFUGAL FURNACE - VOLUME I

    Science.gov (United States)

    A demonstration of the Retech, Inc. Plasma Centrifugal Furnace (PCF) was conducted under the Superfund Innovative Technology Evaluation (SITE) Program at the Department of Energy's (DOE's) Component Development and Integration Facility in Butte, Montana. The furnace uses heat gen...

  14. Centrifuging Step-Screw Conveyor for Regolith Project

    Data.gov (United States)

    National Aeronautics and Space Administration — A variety of ISRU operations will utilize lunar regolith as feedstock. The proposed centrifuging step-screw conveyor concept will provide a well controlled robust,...

  15. Investigation on complete characteristics and hydraulic transient of centrifugal pump

    International Nuclear Information System (INIS)

    An improved method was developed to obtain the complete characteristic of centrifugal pump. The conversion formula of complete characteristics is established based on the normal performance curve. An example was presented to illuminate the new method, and the complete characteristic curves of 14SA-10 centrifugal pump were obtained by the new method. The hydraulic transient of the centrifugal pump failure and start-up was simulated by method of characteristics (MOC), which quote the complete characteristics data. The results show that the inversion method is available to obtain the complete pump characteristic curves provided the normal performance curve. For hydraulic transient simulation, more accurate numerical result can be obtained, if the new model is adopted to convert the experimental normal performance curve to complete characteristics curve of centrifugal pump

  16. Measurement of ground shock in explosive centrifuge model tests

    International Nuclear Information System (INIS)

    Los Alamos National Laboratory has begun a project to simulate the formation and collapse of underground cavities produced by nuclear explosions using chemical explosions at much smaller scale on a large geotechnical centrifuge. Use of a centrifuge for this project presents instrumentation challenges which are not encountered in tests at similar scale off of the centrifuge. Electromagnetic velocity measuring methods which have been very successfully applied to such models at 1 g would be very difficult, if not impossible, to implement at 100 g. We are investigating the feasibility of other techniques for monitoring the ground shock in small-scale tests including accelerometers, stress gauges, dynamic strain meters and small, mutual-inductance particle velocity gauges. Initial results indicate that some of these techniques can be adapted for centrifuge applications. 17 references, 4 figures

  17. Preliminary Study of a Novel Compact R718 Water Chiller With Integration of a Single Stage Centrifugal Compressor and Two-Phase Ejectors

    OpenAIRE

    Sarevski, Milan Nikola; Sarevski, Vasko Nikola

    2012-01-01

    A novel compact R718 water chiller with integration of a centrifugal compressor stage and two phase ejectors as a second stage compression device is proposed. The paper describes the investigations of this R718 refrigerating cycle. The limitations of the R718 centrifugal compressor stage pressure ratio are discussed, and possibilities for introduction of two-phase ejectors in the R718 refrigerating systems with direct evaporation and condensation are analyzed. The complex thermal and flow phe...

  18. Central centrifugal cicatricial alopecia: challenges and solutions.

    Science.gov (United States)

    Herskovitz, Ingrid; Miteva, Mariya

    2016-01-01

    Central centrifugal cicatricial alopecia (CCCA) is the most common scarring alopecia among African American women. Data about epidemiology, etiology, genetic inheritance, and management are scarce and come from individual reports or small series. CCCA has been associated with hot combing and traumatic hair styling for years; however, studies fail to confirm it as the sole etiologic factor. It has been shown in a small series that CCCA can be inherited in an autosomal dominant fashion, with a partial penetrance and a strong modifying effect of hairstyling and sex. CCCA presents clinically as a central area of progressive irreversible hair loss that expands to the periphery. A patchy form has also been described. Dermoscopy is helpful to identify the optimal site for the biopsy, which establishes the diagnosis. Well-designed randomized controlled trials are needed to discover the optimal management. At this point, patients are advised to avoid traction and chemical treatments; topical and intralesional steroids, calcineurin inhibitors, and minoxidil can be helpful in halting the progression. PMID:27574457

  19. Failure analysis of a polymer centrifugal impeller

    Directory of Open Access Journals (Sweden)

    Nikhil K. Kar

    2015-10-01

    Full Text Available A failure analysis investigation was performed on a fractured polymer impeller used in a respiratory blower. Light microscopy, scanning electron microscopy and finite element analysis techniques were utilized to characterize the mode(s of failure and fracture surfaces. A radial split down the impeller center was observed with symmetric fracture faces about the impeller bore. Fractographic analysis revealed brittle fracture features including Wallner lines, mirror, mist and hackle features stemming from the impeller bore, emanating radially outward. Crazed fibrils and faint fatigue striations suggest that intermittent load cycling led to initiation, and rapid propagation of multiple crack fronts originating along the impeller lip. Finite element analysis revealed a flexural condition induces localized stresses along the impeller lip. Significant wear features were also observed within the impeller bore, which may have contributed to premature failure of the impeller. The brittle fracture morphology and defects within the impeller bore suggest that premature failure occurred because of multiple interacting factors including: intermittently high centrifugal velocities, imbalance bore and shaft conditions, defects within the bore caused by machining, and stress concentrations along the circumference of the impeller lip.

  20. Investigation of Flow in a Centrifugal Pump

    Science.gov (United States)

    Fischer, Karl

    1946-01-01

    The investigation of the flow in a centrifugal pump indicated that the flow patterns in frictional fluid are fundamentally different from those in frictionless fluid. In particular, the dead air space adhering to the section side undoubtedly causes a reduction of the theoretically possible delivery head. The velocity distribution over a parallel circle is also subjected to a noticeable change as a result of the incomplete filling of the passages. The relative velocity on the pressure side of the vane, which for passages completely filled with active flow would differ little from zero even at comparatively lower than normal delivery volume, is increased, so that no rapid reverse flow occurs on the pressure side of the vane even for smaller delivery volume. It was established, further, that the flow ceases to be stationary for very small quantities of water. The inflow to the impeller can be regarded as radial for the operating range an question. The velocity triangles at the exit are subjected to a significant alteration in shape ae a result of the increased peripheral velocity, which may be of particular importance in the determination of the guide vane entrance angle.

  1. Central centrifugal cicatricial alopecia: challenges and solutions.

    Science.gov (United States)

    Herskovitz, Ingrid; Miteva, Mariya

    2016-01-01

    Central centrifugal cicatricial alopecia (CCCA) is the most common scarring alopecia among African American women. Data about epidemiology, etiology, genetic inheritance, and management are scarce and come from individual reports or small series. CCCA has been associated with hot combing and traumatic hair styling for years; however, studies fail to confirm it as the sole etiologic factor. It has been shown in a small series that CCCA can be inherited in an autosomal dominant fashion, with a partial penetrance and a strong modifying effect of hairstyling and sex. CCCA presents clinically as a central area of progressive irreversible hair loss that expands to the periphery. A patchy form has also been described. Dermoscopy is helpful to identify the optimal site for the biopsy, which establishes the diagnosis. Well-designed randomized controlled trials are needed to discover the optimal management. At this point, patients are advised to avoid traction and chemical treatments; topical and intralesional steroids, calcineurin inhibitors, and minoxidil can be helpful in halting the progression.

  2. Central centrifugal cicatricial alopecia: challenges and solutions

    Directory of Open Access Journals (Sweden)

    Herskovitz I

    2016-08-01

    Full Text Available Ingrid Herskovitz, Mariya Miteva Department of Dermatology and Cutaneous Surgery, University of Miami L Miller School of Medicine, Miami, FL, USA Abstract: Central centrifugal cicatricial alopecia (CCCA is the most common scarring alopecia among African American women. Data about epidemiology, etiology, genetic inheritance, and management are scarce and come from individual reports or small series. CCCA has been associated with hot combing and traumatic hair styling for years; however, studies fail to confirm it as the sole etiologic factor. It has been shown in a small series that CCCA can be inherited in an autosomal dominant fashion, with a partial penetrance and a strong modifying effect of hairstyling and sex. CCCA presents clinically as a central area of progressive irreversible hair loss that expands to the periphery. A patchy form has also been described. Dermoscopy is helpful to identify the optimal site for the biopsy, which establishes the diagnosis. Well-designed randomized controlled trials are needed to discover the optimal management. At this point, patients are advised to avoid traction and chemical treatments; topical and intralesional steroids, calcineurin inhibitors, and minoxidil can be helpful in halting the progression. Keywords: hair loss, alopecia, dermatoscopy, dermoscopy, trichoscopy, black scalp, African American, scarring alopecia

  3. Centrifugal Liquid/Gas Separator With Phase Detectors

    Science.gov (United States)

    Schneider, Steven J.

    1994-01-01

    Centrifugal liquid/gas separator that includes phase (liquid or gas) detectors helps ensure exclusiveness of each phase at its assigned outlet. Acoustic sensors in centrifugal liquid/gas separator measure speeds of sound in nominally pure liquid and nominally pure gas at liquid and gas outlets respectively. When speed of sound is that of pure liquid or gas, valve opens to let liquid or gas flow out.

  4. Design Method for Channel Diffusers of Centrifugal Compressors

    OpenAIRE

    Mykola Kalinkevych; Andriy Skoryk

    2013-01-01

    The design method for channel diffusers of centrifugal compressors, which is based on the solving of the inverse problem of gas dynamics, is presented in the paper. The concept of the design is to provide high pressure recovery of the diffuser by assuming the preseparation condition of the boundary layer along one of the channel surfaces. The channel diffuser was designed with the use of developed method to replace the vaned diffuser of the centrifugal compressor model stage. The numerical si...

  5. Non Adiabatic Centrifugal Compressor Gas Dynamic Performance Definition

    OpenAIRE

    Soldatova, Kristina

    2014-01-01

    Most centrifugal compressors operate in conditions with negligible heat transfer (adiabatic compression). Their plant tests conditions are similar or close to adiabatic conditions. Test regulations establish measures to diminish influence of a heat transfer “compressor body – atmospheric air” to an exit temperature. Therefore a temperature rise in a compressor is used to calculate a work input coefficient and efficiency. Unlike it high pressure centrifugal compressors of gas turbines and supe...

  6. Numerical Calculation on Cavitation Pressure Pulsation in Centrifugal Pump

    OpenAIRE

    Weidong Shi; Chuan Wang; Wei Wang; Bing Pei

    2014-01-01

    In order to study the internal flow in centrifugal pump when cavitation occurs, numerical calculation of the unsteady flow field in the WP7 automobile centrifugal pump is conducted based on the Navier-Stokes equations with the RNG k-ε turbulence model and Zwart-Gerber-Belamri cavitation model. The distributions of bubble volume fraction and pressure pulsation laws in the pump are analyzed when cavitation occurs. The conclusions are as follows: the bubble volume fraction is larger on the sucti...

  7. Effect of Perturbations in the Coriolis and Centrifugal Forces on the Stability of 4 in the Relativistic R3BP

    Indian Academy of Sciences (India)

    Jagadish Singh; Nakone Bello

    2014-12-01

    The centrifugal and Coriolis forces do not appear as a result of physically imposed forces, but are due to a special property of a rotation. Thus, these forces are called pseudo-forces or `fictitious forces’. They are merely an artifact of the rotation of the reference frame adopted. This paper studies the motion of a test particle in the neighbourhood of the triangular point 4 in the framework of the perturbed relativistic restricted three-body problem (R3BP) when small perturbations are conferred to the centrifugal and Coriolis forces. It is found that the position and stability of the triangular point are affected by both the relativistic factor and small perturbations in the Coriolis and centrifugal forces. As an application, the Sun–Earth system is considered.

  8. In vitro study to estimate particle release from a centrifugal blood pump.

    Science.gov (United States)

    Takami, Yoshiyuki

    2006-05-01

    Centrifugal pumps have been increasingly used in clinical settings. Like roller pumps, centrifugal pumps can cause debris release due to mechanical stress. The objectives of this study were to evaluate in vitro the particle release from a centrifugal pump, Gyro Pump (Japan Medical Materials Co., Osaka, Japan), which is a pivot-bearing supported pump clinically used in Japan, and to identify the released particles. In the clean room Class 10,000, the pump was operated for 24 h at 4000 rpm and 6 L/min in a mock loop filled with lactated Ringer's solution. After 24 h, the sample fluid and a blank were filtered with a 0.45-microm membrane filter for microscopic counting, followed by observation with a scanning electron microscope and element analysis with an X-ray spectrometer. Microscopic countings were 128 +/- 42 in the test samples (n = 10) of the Gyro Pump and 98 +/- 42 in the blank samples (n = 10) (P = 0.12). The oxygen/carbon atomic ratio of the particles in the test samples was 0.32 +/- 0.06, which was similar to the ratio of the particles in the blank sample (0.34 +/- 0.06). The profiles of elements with an X-ray spectrometer showed that the released particles from the Gyro Pump were not derived from the pump materials. In conclusion, an in vitro test system has been established for estimation of particle release from a centrifugal pump. Based upon the results with the system, the Gyro Pump with a pivot-bearing system has little risk to release debris particles even in a severe condition.

  9. Entrainment and phase-shifting by centrifugation abolished in mice lacking functional vestibular input

    Science.gov (United States)

    Fuller, Charles; Ringgold, Kristyn

    The circadian pacemaker can be phase shifted and entrained by appropriately timed locomotor activity, however the mechanism(s) involved remain poorly understood. Recent work in our lab has suggested the involvement of the vestibular otolith organs in activity-induced changes within the circadian timing system (CTS). For example, we have shown that changes in circa-dian period and phase in response to locomotion (wheel running) require functional macular gravity receptors. We believe the neurovestibular system is responsible for the transduction of gravitoinertial input associated with the types of locomotor activity that are known to af-fect the pacemaker. This study investigated the hypothesis that daily, timed gravitoinertial stimuli, as applied by centrifugation. would induce entrainment of circadian rhythms in only those animals with functional afferent vestibular input. To test this hypothesis, , chemically labyrinthectomized (Labx) mice, mice lacking macular vestibular input (head tilt or hets) and wildtype (WT) littermates were implanted i.p. with biotelemetry and individually housed in a 4-meter diameter centrifuge in constant darkness (DD). After 2 weeks in DD, the mice were exposed daily to 2G via centrifugation from 1000-1200 for 9 weeks. Only WT mice showed entrainment to the daily 2G pulse. The 2G pulse was then re-set to occur at 1200-1400 for 4 weeks. Only WT mice demonstrated a phase shift in response to the re-setting of the 2G pulse and subsequent re-entrainment to the new centrifugation schedule. These results provide further evidence that gravitoinertial stimuli require a functional vestibular system to both en-train and phase shift the CTS. Entrainment among only WT mice supports the role of macular gravity receptive cells in modulation of the CTS while also providing a functional mechanism by which gravitoinertial stimuli, including locomotor activity, may affect the pacemaker.

  10. Feedback Control and Dynamic Behaviour of Z-Source Converter Fed Separately Excited DC Motor and Centrifugal Pump Set

    Directory of Open Access Journals (Sweden)

    Saswati Swapna Dash

    2014-07-01

    Full Text Available This paper presents an overall study of Feedback Control of Z-Source Converter Fed Separately excited DC motor with centrifugal Pump Set. Z-source converter can be used for both voltage buck and boost mode using LC impedance network. In this paper the dynamic modeling of Z-source with motor load and centrifugal pump set is carried out with new findings. The compensators for speed feedback loop are designed by taking average state space analysis and small signal model of the system. The feedback loop is designed by classical control methods. The experiment is done in MATLAB work environment and the result is verified by Simulation.

  11. Feedback Control and Dynamic Behaviour of Z-Source Converter Fed Separately Excited DC Motor and Centrifugal Pump Set

    OpenAIRE

    Saswati Swapna Dash; Byamakesh Nayak; Subrat Kumar

    2014-01-01

    This paper presents an overall study of Feedback Control of Z-Source Converter Fed Separately excited DC motor with centrifugal Pump Set. Z-source converter can be used for both voltage buck and boost mode using LC impedance network. In this paper the dynamic modeling of Z-source with motor load and centrifugal pump set is carried out with new findings. The compensators for speed feedback loop are designed by taking average state space analysis and small signal model of the system. The feedba...

  12. Centrifugal potential energy : an astounding renewable energy concept

    Energy Technology Data Exchange (ETDEWEB)

    Oduniyi, I.A. [Aled Conglomerate Nigeria Ltd., Lagos (Nigeria)

    2010-07-01

    A new energy concept known as centrifugal potential energy was discussed. This new energy concept is capable of increasing the pressure, temperature and enthalpy of a fluid, without having to apply work or heat transfer to the fluid. It occurs through a change in the centrifugal potential energy of the flowing fluid in a rotating frame of reference or a centrifugal force field, where work is performed internally by the centrifugal weight of the fluid. This energy concept has resulted in new energy equations, such as the Rotational Frame Bernoulli's Equation for liquids and the Rotational Frame Steady-Flow Energy Equation for gases. Applications of these equations have been incorporated into the design of centrifugal field pumps and compressors. Rather than compressing a fluid with a physical load transfer, these devices can compress a fluid via the effect of centrifugal force applied to the object. A large amount of energy is therefore produced when this high pressure compressed working fluid expands in a turbine. When water is used as the working fluid, it could reach renewable energy densities in the range of 25-100 kJ/kg of water. When atmospheric air is used, it could reach energy densities in the range of 500-1,500 kJ/kg of air.

  13. Investigation into the Interaction of Centrifugal Compressor Impeller and Vaneless Diffuser

    Institute of Scientific and Technical Information of China (English)

    YANG Ce; ZHANG Dian-zuo; MA Chao-chen; HU Liao-ping

    2006-01-01

    Centrifugal compressors with parallel-wall and contracting wall vaneless diffuser are designed by using centrifugal compressor computer-aided integrated design system. The internal flow fields of the compressor are calculated by solving three-dimensional Navier-Stokes equation. Four aspects are investigated and calculation results show that the total efficiencies and total pressure ratios of the compressor with contracting wall vaneless diffuser is higher than that of the compressor with parallel-wall. The jet and wake don't mix rapidly inside vaneless diffuser. The outlet blade lean angle doesn't affect the compressor performance. The greater the mass flow rate through impeller, the more uneven the velocity distribution at impeller outlet is.

  14. Effect of double air injection on performance characteristics of centrifugal compressor

    Science.gov (United States)

    Hirano, Toshiyuki; Takano, Mizuki; Tsujita, Hoshio

    2015-02-01

    In the operation of a centrifugal compressor of turbocharger, instability phenomena such as rotating stall and surge are induced at a lower flow rate close to the maximum pressure ratio. In this study, for the suppression of surge phenomenon resulting in the extension of the stable operating range of centrifugal compressor to lower flow rate, the compressed air at the compressor exit was re-circulated and injected into the impeller inlet by using the double injection nozzle system. The experiments were performed to find out the optimum circumferential position of the second nozzle relative to the fixed first one and the optimum inner diameter of the injection nozzles, which are able to most effectively reduce the flow rate of surge inception. Moreover, in order to examine the universality of these optimum values, the experiments were carried out for two types of compressors.

  15. Fabrication of highly aligned fibrous scaffolds for tissue regeneration by centrifugal spinning technology

    Energy Technology Data Exchange (ETDEWEB)

    Loordhuswamy, Amalorpava Mary [Department of Textile Technology, Anna University, Chennai 600025 (India); Krishnaswamy, Venkat Raghavan; Korrapati, Purna Sai [Department of Biomaterials, CSIR-Central Leather Research Institute, Chennai 600020 (India); Thinakaran, Senthilram [Department of Textile Technology, Anna University, Chennai 600025 (India); Rengaswami, Giri Dev Venkateshwarapuram, E-mail: vrgiridev@yahoo.com [Department of Textile Technology, Anna University, Chennai 600025 (India)

    2014-09-01

    Centrifugal spinning (C-Spin) is an emerging technology which uses centrifugal force to produce ultrafine fibers. Being a voltage free technique it can overcome the limitations of electrospinning. Owing to the unique characteristic features such as high surface area to volume ratio, porosity, mechanical strength and fiber alignment, centrifugal spun (C-spun) fibrous mat has a wide range of scope in various biomedical applications. Higher degree of fiber alignment can be effortlessly achieved by the C-Spin process. In order to prove the versatility of C-Spin system with respect to fiber alignment, Polycaprolactone (PCL) and gelatin were spun taking them as model polymers. The morphological analysis revealed that highly aligned ultrafine fibers with smooth surface are achieved by C-Spinning. Hydrophilicity, porosity and mechanical property results confirm that the C-spun mat is more suitable for tissue engineering applications. In vitro and in vivo experiments proved that the scaffolds are biocompatible and can be efficiently used as a wound dressing material. - Highlights: • Highly aligned PCL/gelatin fibrous scaffolds were prepared by C-Spinning system. • Degree of fiber alignment was influenced by the proportion of gelatin in the blends. • Direction of cell growth was parallel to the direction of fiber alignment. • C-Spun matrices can efficiently accelerate faster wound healing.

  16. Hemocompatibility of Axial Versus Centrifugal Pump Technology in Mechanical Circulatory Support Devices.

    Science.gov (United States)

    Schibilsky, David; Lenglinger, Matthias; Avci-Adali, Meltem; Haller, Christoph; Walker, Tobias; Wendel, Hans Peter; Schlensak, Christian

    2015-08-01

    The hemocompatible properties of rotary blood pumps commonly used in mechanical circulatory support (MCS) are widely unknown regarding specific biocompatibility profiles of different pump technologies. Therefore, we analyzed the hemocompatibility indicating markers of an axial flow and a magnetically levitated centrifugal device within an in vitro mock loop. The HeartMate II (HM II; n = 3) device and a CentriMag (CM; n = 3) adult pump were investigated in a human whole blood mock loop for 360 min using the MCS devices as a driving component. Blood samples were analyzed by enzyme-linked immunosorbent assay for markers of coagulation, complement system, and inflammatory response. There was a time-dependent activation of the coagulation (thrombin-antithrombin complexes [TAT]), complement (SC5b-9), and inflammation system (polymorphonuclear [PMN] elastase) in both groups. The mean value of TAT (CM: 4.0 μg/L vs. 29.4 μg/L, P centrifugal CM device showed significantly lower activation of coagulation and inflammation than that of the HM II axial flow pump. Both HM II and CM have demonstrated an acceptable hemocompatibility profile in patients. However, there is a great opportunity to gain a clinical benefit by developing techniques to lower the blood surface interaction within both pump technologies and a magnetically levitated centrifugal pump design might be superior.

  17. Experimental and numerical investigation of centrifugal pumps with asymmetric inflow conditions

    Science.gov (United States)

    Mittag, Sten; Gabi, Martin

    2015-11-01

    Most of the times pumps operate off best point states. Reasons are changes of operating conditions, modifications, pollution and wearout or erosion. As consequences non-rotational symmetric flows, transient operational conditions, increased risk of cavitation, decrease of efficiency and unpredictable wearout can appear. Especially construction components of centrifugal pumps, in particular intake elbows, contribute to this matter. Intake elbows causes additional losses and secondary flows, hence non-rotational velocity distributions as intake profile to the centrifugal pump. As a result the impeller vanes experience permanent changes of the intake flow angle and with it transient flow conditions in the blade channels. This paper presents the first results of a project, experimentally and numerically investigating the consequences of non-rotational inflow to leading edge flow conditions of a centrifugal pump. Therefore two pumpintake- elbow systems are compared, by only altering the intake elbow geometry: a common single bended 90° elbow and a numerically optimized elbow (improved regarding rotational symmetric inflow conditions and friction coefficient). The experiments are carried out, using time resolved stereoscopic PIV on a full acrylic pump with refractions index matched (RIM) working fluid. This allows transient investigations of the flow field simultaneously for all blade leading edges. Additional CFD results are validated and used to further support the investigation i.e. for comparing an analog pump system with ideal inflow conditions.

  18. Hemocompatibility of Axial Versus Centrifugal Pump Technology in Mechanical Circulatory Support Devices.

    Science.gov (United States)

    Schibilsky, David; Lenglinger, Matthias; Avci-Adali, Meltem; Haller, Christoph; Walker, Tobias; Wendel, Hans Peter; Schlensak, Christian

    2015-08-01

    The hemocompatible properties of rotary blood pumps commonly used in mechanical circulatory support (MCS) are widely unknown regarding specific biocompatibility profiles of different pump technologies. Therefore, we analyzed the hemocompatibility indicating markers of an axial flow and a magnetically levitated centrifugal device within an in vitro mock loop. The HeartMate II (HM II; n = 3) device and a CentriMag (CM; n = 3) adult pump were investigated in a human whole blood mock loop for 360 min using the MCS devices as a driving component. Blood samples were analyzed by enzyme-linked immunosorbent assay for markers of coagulation, complement system, and inflammatory response. There was a time-dependent activation of the coagulation (thrombin-antithrombin complexes [TAT]), complement (SC5b-9), and inflammation system (polymorphonuclear [PMN] elastase) in both groups. The mean value of TAT (CM: 4.0 μg/L vs. 29.4 μg/L, P centrifugal CM device showed significantly lower activation of coagulation and inflammation than that of the HM II axial flow pump. Both HM II and CM have demonstrated an acceptable hemocompatibility profile in patients. However, there is a great opportunity to gain a clinical benefit by developing techniques to lower the blood surface interaction within both pump technologies and a magnetically levitated centrifugal pump design might be superior. PMID:26234452

  19. A wireless centrifuge force microscope (CFM) enables multiplexed single-molecule experiments in a commercial centrifuge

    Science.gov (United States)

    Hoang, Tony; Patel, Dhruv S.; Halvorsen, Ken

    2016-08-01

    The centrifuge force microscope (CFM) was recently introduced as a platform for massively parallel single-molecule manipulation and analysis. Here we developed a low-cost and self-contained CFM module that works directly within a commercial centrifuge, greatly improving accessibility and ease of use. Our instrument incorporates research grade video microscopy, a power source, a computer, and wireless transmission capability to simultaneously monitor many individually tethered microspheres. We validated the instrument by performing single-molecule force shearing of short DNA duplexes. For a 7 bp duplex, we observed over 1000 dissociation events due to force dependent shearing from 2 pN to 12 pN with dissociation times in the range of 10-100 s. We extended the measurement to a 10 bp duplex, applying a 12 pN force clamp and directly observing single-molecule dissociation over an 85 min experiment. Our new CFM module facilitates simple and inexpensive experiments that dramatically improve access to single-molecule analysis.

  20. A wireless centrifuge force microscope (CFM) enables multiplexed single-molecule experiments in a commercial centrifuge.

    Science.gov (United States)

    Hoang, Tony; Patel, Dhruv S; Halvorsen, Ken

    2016-08-01

    The centrifuge force microscope (CFM) was recently introduced as a platform for massively parallel single-molecule manipulation and analysis. Here we developed a low-cost and self-contained CFM module that works directly within a commercial centrifuge, greatly improving accessibility and ease of use. Our instrument incorporates research grade video microscopy, a power source, a computer, and wireless transmission capability to simultaneously monitor many individually tethered microspheres. We validated the instrument by performing single-molecule force shearing of short DNA duplexes. For a 7 bp duplex, we observed over 1000 dissociation events due to force dependent shearing from 2 pN to 12 pN with dissociation times in the range of 10-100 s. We extended the measurement to a 10 bp duplex, applying a 12 pN force clamp and directly observing single-molecule dissociation over an 85 min experiment. Our new CFM module facilitates simple and inexpensive experiments that dramatically improve access to single-molecule analysis. PMID:27587129

  1. Parametric representation of centrifugal pump homologous curves

    Energy Technology Data Exchange (ETDEWEB)

    Veloso, Marcelo A.; Mattos, Joao R.L. de, E-mail: velosom@cdtn.br, E-mail: jrmattos@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2015-07-01

    Essential for any mathematical model designed to simulate flow transient events caused by pump operations is the pump performance data. The performance of a centrifugal pump is characterized by four basic quantities: the rotational speed, the volumetric flow rate, the dynamic head, and the hydraulic torque. The curves showing the relationships between these four variables are called the pump characteristic curves. The characteristic curves are empirically developed by the pump manufacturer and uniquely describe head and torque as functions of volumetric flow rate and rotation speed. Because of comprising a large amount of points, this configuration is not suitable for computational purposes. However, it can be converted to a simpler form by the development of the homologous curves, in which dynamic head and hydraulic torque ratios are expressed as functions of volumetric flow and rotation speed ratios. The numerical use of the complete set of homologous curves requires specification of sixteen partial curves, being eight for the dynamic head and eight for the hydraulic torque. As a consequence, the handling of homologous curves is still somewhat complicated. In solving flow transient problems that require the pump characteristic data for all the operation zones, the parametric form appears as the simplest way to deal with the homologous curves. In this approach, the complete characteristics of a pump can be described by only two closed curves, one for the dynamic head and other for the hydraulic torque, both in function of a single angular coordinate defined adequately in terms of the quotient between volumetric flow ratio and rotation speed ratio. The usefulness and advantages of this alternative method are demonstrated through a practical example in which the homologous curves for a pump of the type used in the main coolant loops of a pressurized water reactor (PWR) are transformed to the parametric form. (author)

  2. Hydrodynamic performance and heat generation by centrifugal pumps.

    Science.gov (United States)

    Ganushchak, Y; van Marken Lichtenbelt, W; van der Nagel, T; de Jong, D S

    2006-11-01

    For over a century, centrifugal pumps (CP) have been used in various applications, from large industrial pumps to flow pumps for aquariums. However, the use of CP as blood pumps has a rather short history. Consequently, the hydraulic performance data for a blood CP are limited. The aim of our investigation was to study the hydraulic performance and the heat generation of three commercially available CP: Bio-Medicus Bio-Pump BP80 (Medtronic), Rotaflow (Jostra Medizintechnik), and DeltaStream DP2 (MEDOS Medizintechnik AQ). The study was performed using a circuit primed with a water-glycerin mixture with a dynamic viscosity of 0.00272 pa/s. Pressure-flow curves were obtained by a stepwise stagnation of the pump outlet or inlet. The temperature changes were observed using ThermaCAM SC2000 (Flir Systems). The pumps' performance in close to clinical conditions ('operating region') was analysed in this report. The 'operating region' in the case of the BP80 is positioned around the pressure-flow curve at a pump speed of 3000 rpm. In the case of the Rotaflow, the 'operating region' was between the pump pressure-flow curves at a speed of 3000 and 4000 rpm, and the DP2 was found between 7000 and 8000 rpm. The standard deviation of mean pressure through the pump was used to characterise the stability of the pump. In experiments with outlet stagnation, the BP80 demonstrated high negative association between flow and pressure variability (r = -0.68, p pumps demonstrated significantly higher variability of pressure in experiments with inlet stagnation in comparison to the experiments with outlet stagnation. The rise of relative temperature in the inlet of a pump was closely related to the flow rate. The heating of fluid was more pronounced in the 'zero-flow' mode, especially in experiments with inlet stagnation. In summary, (1) the 'zero-flow' regime, which is described in the manuals of some commercially-available pumps, is the use of the pump outside the allowable operating

  3. Solanidine isolation from Solanum tuberosum by centrifugal partition chromatography.

    Science.gov (United States)

    Attoumbré, Jacques; Giordanengo, Philippe; Baltora-Rosset, Sylvie

    2013-07-01

    The aim of this investigation was the preparative isolation of solanidine (aglycone of the two main potato glycoalkaloids: α-chaconine and α-solanine) from fresh Solanum tuberosum (cv. Pompadour) material by implementing a new preparation scheme using centrifugal partition chromatography (CPC). A setup for obtaining solanidine by hydrolysis of the glycoalkaloids found in the skin and sprouts of S. tuberosum was first developed. Then its isolation was carried out by the development of CPC conditions: the solvent system used for separation was ethyl acetate/butanol/water in the ratio 42.5:7.5:50 v/v/v, 0.6 g of crude extract were separated with a 8 mL/min flow rate of mobile phase while rotating at 2500 rpm. A run yielded 98 mg of solanidine (86.7% recovery from the crude extract) in a one-step separation. The purity of the isolated solanidine was over 98%. Thus, CPC has proven to be the method of choice to get solanidine of very high purity from S. tuberosum biomass in large quantities.

  4. Isolation of Methoxyfuranocoumarins From Ammi majus by Centrifugal Partition Chromatography.

    Science.gov (United States)

    Bartnik, Magdalena; Mazurek, Anna Katarzyna

    2016-01-01

    Pure methoxyfuranocoumarins were isolated from Ammi majus L. by use of low-pressure column chromatography (LPCC) followed by centrifugal partition chromatography (CPC). The concentrated petroleum ether extract from fruits of A. majus was fractionated on a silica gel column using a gradient of ethyl acetate in dichloromethane (0-80%, v/v). Coumarin-rich fractions were analyzed by thin-layer chromatography (TLC) and high-performance liquid chromatography with diode array detection (HPLC/DAD). Xanthotoxin (8-MOP) and isopimpinellin (isoP), structurally similar compounds, were isolated in one fraction (FR6). To avoid multistep and long-lasting TLC preparation, optimization of CPC conditions has been performed. In one run, an effective separation of 8-MOP and isoP was achieved. The two-phase solvent system composed of n-hexane-ethyl acetate-methanol-water (10 : 8 : 10 : 9; v/v) in an ascending mode (the aqueous phase was a stationary phase, and the organic phase was a mobile phase), with flow rate 3 mL/min and rotation speed 1,600 r.p.m., was used. The identification and high purities of isolated 8-MOP (98.7%) and isoP (100%) were confirmed by HPLC/DAD assay, when compared with standards. The developed CPC method could be applied to the effective isolation of 8-MOP and isoP from plant extracts. The high purity of obtained compounds makes possible further exploitation of these components in biological studies.

  5. Experimental on-stream elimination of resonant whirl in a large centrifugal compressor

    Science.gov (United States)

    Bhat, G. I.; Eierman, R. G.

    1984-01-01

    Resonant whirl condition during operation of a multi-stage centrifugal compressor at higher than anticipated speeds and loads was reported. The condition was diagnosed by a large scale computerized Machinery Condition Monitoring System (MACMOS). This computerized system verified that the predominant subsynchronous whirl frequency locked in on the first resonant frequency of the compressor rotor and did not vary with compressor speed. Compressor stability calculations showed the rotor system had excessive hearing stiffness and inadequate effective damping. An optimum bearing design which was developed to minimize the unbalance response and to maximize the stability threshold is presented.

  6. Concentration and Purification of Poliovirus by Ultrafiltration and Isopycnic Centrifugation1

    Science.gov (United States)

    Guskey, Louis E.; Wolff, David A.

    1972-01-01

    A method is described by which poliovirus can be rapidly and simply concentrated by the use of a Diaflo XM-50 ultrafilter membrane. Freon-extracted ultrafilter concentrates banded in CsCl provided a 1,724-fold volumetric concentration of poliovirus. During concentration, trypsin-digested cellular material can pass through the ultrafilter membrane, thus providing a versatile means of degrading and eliminating extraneous contaminating proteins. The ultrafilter concentration system is compared with the CsCl cushion system of poliovirus concentration, and both systems are further compared by banding virus and virus capsid material in CsCl by use of isopycnic centrifugation. Images PMID:4341520

  7. Towards an optimized flow-sheet for a SANEX demonstration process using centrifugal contactors

    Energy Technology Data Exchange (ETDEWEB)

    Magnusson, D. [European Commission, Joint Research Center, Karlsruhe (Germany). Inst. for Transuranium Elements; Chalmers Univ. of Technology, Gothenburg (Sweden). Nuclear Chemistry, Dept. of Chemical and Biological Engineering; Christiansen, B.; Glatz, J.P.; Malmbeck, R.; Serrano-Purroy, D. [European Commission, Joint Research Center, Karlsruhe (Germany). Inst. for Transuranium Elements; Modolo, G. [Forschungszentrum Juelich GmbH (Germany). Inst. for Energy Research, Safety Research and Reactor Technology; Sorel, C. [Commissariat a l' Energie Atomique Valrho (CEA), DRCP/SCPS, Bagnols-sur-Ceze (France)

    2009-07-01

    The design of an efficient process flow-sheet requires accurate extraction data for the experimental set-up used. Often this data is provided as equilibrium data. Due to the small hold-up volume compared to the flow rate in centrifugal contactors the time for extraction is often too short to reach equilibrium D-ratios. In this work single stage kinetics experiments have been carried out to investigate the D-ratio dependence of the flow rate and to compare this with equilibrium batch experiments for a SANEX system based on CyMe{sub 4}-BTBP. The first centrifuge experiment was run with spiked solutions while in the second a genuine actinide/lanthanide fraction from a TODGA process was used. Three different flow rates were tested with each set-up. The results show that even with low flow rates, only around 9% of the equilibrium D-ratio (Am) was reached for the extraction in the spiked test and around 16% in the hot test (the difference is due to the size of the centrifuges). In the hot test the lanthanide scrubbing was inefficient whereas in the stripping both the actinides and the lanthanides showed good results. Based on these results improvements of the suggested flow-sheet is discussed. (orig.)

  8. Research on the induction motor current signature for centrifugal pump at cavitation condition

    Directory of Open Access Journals (Sweden)

    Yin Luo

    2015-11-01

    Full Text Available Cavitation is a major undesirable phenomenon for centrifugal pump because it can cause hydraulic performance deterioration, pump damage by pitting and material erosion, and structural vibration and noise. Cavitation can appear within the entire range of the operating conditions; therefore, it must be prevented by all means. Sensorless monitoring technology based on motor current signature analysis is non-intrusive and economic for monitoring motor-driven equipment. Thus, this technology is suitable for centrifugal pump systems. The motor current signature for centrifugal pump load at the cavitation condition is the basis of this technology. However, systematic research is lacking on sensorless monitoring technology based on motor current signature. As a result, the tentative exploration for motor current signature at cavitation load was conducted in this study. The results show that the stator current is still a sinusoidal alternating current strictly to the law of sine. Moreover, the root mean square of the current fluctuates because of different flow regimes in the cavitation progress and decreases because vapor density is smaller than water density when cavitation is fully formed. For the stator current spectrum, the noise level, noise distribution, rotation speed, and vane pass frequency components show features in the cavitation process. These indicator indexes change according to the stage of cavitation development. Thus, the motor current signature analysis is found to be a feasible and cost-effective method for the stages of cavitation condition.

  9. Rotordynamic forces generated by discharge-to-suction leakage flows in centrifugal pumps

    Institute of Scientific and Technical Information of China (English)

    LIU Quan-zhong; WANG Hong-jie; LIU Zhan-sheng

    2009-01-01

    In order to investigate the flow-induced vibration in the shroud passage of centrifugal pump and pre-dict rotordynamic forces of centrifugal pump rotor system,an analysis of rotordynamic forces arising from shrou-ded centnlugal pump is presented.CFD techniques were utilized to analyze the full three-dimensional viscous,primary/secondary flow field in a centrifugal pump impeller to determine rotordynamic forces. Multiple quasi-steady solutions of an eccentric three-dimensional model at different whirl frequency ratios yielded the rotordy-namic forces. The skew-symmetric stiffness,damping,and mass matrices were obtained by second-order least-squares analysis.Simulation of the coupled primary/secondary flow field was conducted,and the complex flow characteristcs.in the flow field of a shroud passage were achieved including the mean velocity and pressure,as well as the eddy in a large scale of flow field due to viscosity.The rotordynamic force coefficients were calculat-ed,and the results were in good agreement with those of experiment except for the direct inertial coefficient without the consideration of whirling forces from the impeller primary flow passage.

  10. Fabrication of highly aligned fibrous scaffolds for tissue regeneration by centrifugal spinning technology.

    Science.gov (United States)

    Loordhuswamy, Amalorpava Mary; Krishnaswamy, Venkat Raghavan; Korrapati, Purna Sai; Thinakaran, Senthilram; Rengaswami, Giri Dev Venkateshwarapuram

    2014-09-01

    Centrifugal spinning (C-Spin) is an emerging technology which uses centrifugal force to produce ultrafine fibers. Being a voltage free technique it can overcome the limitations of electrospinning. Owing to the unique characteristic features such as high surface area to volume ratio, porosity, mechanical strength and fiber alignment, centrifugal spun (C-spun) fibrous mat has a wide range of scope in various biomedical applications. Higher degree of fiber alignment can be effortlessly achieved by the C-Spin process. In order to prove the versatility of C-Spin system with respect to fiber alignment, Polycaprolactone (PCL) and gelatin were spun taking them as model polymers. The morphological analysis revealed that highly aligned ultrafine fibers with smooth surface are achieved by C-Spinning. Hydrophilicity, porosity and mechanical property results confirm that the C-spun mat is more suitable for tissue engineering applications. In vitro and in vivo experiments proved that the scaffolds are biocompatible and can be efficiently used as a wound dressing material.

  11. Task 9 - Centrifugal membrane filtration. Semi-annual report, April 1 - September 30, 1997

    International Nuclear Information System (INIS)

    This project is designed to establish the utility of a novel centrifugal membrane filtration technology for the remediation of liquid mixed waste streams at US Department of Energy (DOE) facilities in support of the DOE Environmental Management (EM) program. The Energy and Environmental Research Center (EERC) has teamed with SpinTek Membrane Systems, Inc., a small business and owner of the novel centrifugal membrane filtration technology, to establish the applicability of the technology to DOE site remediation and the commercial viability of the technology for liquid mixed waste stream remediation. The technology is a uniquely configured process that makes use of ultrafiltration and centrifugal force to separate suspended and dissolved solids from liquid waste streams, producing a filtered water stream and a low-volume contaminated concentrate stream. This technology has the potential for effective and efficient waste volume minimization, the treatment of liquid tank wastes, the remediation of contaminated groundwater plumes, and the treatment of secondary liquid waste streams from other remediation processes, as well as the liquid waste stream generated during decontamination and decommissioning activities

  12. Challenges and Opportunities of Centrifugal Microfluidics for Extreme Point-of-Care Testing

    Directory of Open Access Journals (Sweden)

    Issac J. Michael

    2016-02-01

    Full Text Available The advantages offered by centrifugal microfluidic systems have encouraged its rapid adaptation in the fields of in vitro diagnostics, clinical chemistry, immunoassays, and nucleic acid tests. Centrifugal microfluidic devices are currently used in both clinical and point-of-care settings. Recent studies have shown that this new diagnostic platform could be potentially used in extreme point-of-care settings like remote villages in the Indian subcontinent and in Africa. Several technological inventions have decentralized diagnostics in developing countries; however, very few microfluidic technologies have been successful in meeting the demand. By identifying the finest difference between the point-of-care testing and extreme point-of-care infrastructure, this review captures the evolving diagnostic needs of developing countries paired with infrastructural challenges with technological hurdles to healthcare delivery in extreme point-of-care settings. In particular, the requirements for making centrifugal diagnostic devices viable in developing countries are discussed based on a detailed analysis of the demands in different clinical settings including the distinctive needs of extreme point-of-care settings.

  13. Study of flow instability in a centrifugal fan based on energy gradient theory

    Energy Technology Data Exchange (ETDEWEB)

    Xiao, Meina; Dou, Hua-Shu; Ma, Xiaoyang [Zhejiang Sci-Tech University, Hangzhou (China); Xiao, Qing [University of Strathclyde, Glasgow (United Kingdom); Chen, Yongning; He, Haijiang; Ye, Xinxue [Zhejiang Yilida Ventilator Co. Ltd, Taizhou (China)

    2016-02-15

    Flow instability in a centrifugal fan was studied using energy gradient theory. Numerical simulation was performed for the three dimensional turbulent flow field in a centrifugal fan. The flow is governed by the three-dimensional incompressible Navier-Stokes equations coupled with the RNG k-ε turbulent model. The finite volume method was used to discretize the governing equations and the Semiimplicit method for pressure linked equation (SIMPLE) algorithm is employed to iterate the system of the equations. The interior flow field in the centrifugal fan and the distribution of the energy gradient function K are obtained at different flow rates. According to the energy gradient method, the area with larger value of K is the place where the flow loses stability easier. The results show that instability is easier to generate in the regions of impeller outlet and volute tongue. The air flow near the hub is more stable than that near the shroud. That is due to the influences of variations of the velocity and the inlet angle along the axial direction. With the decrease of the flow rate, instability zone in a blade channel moves to the impeller inlet from the outlet and the unstable regions in different channels develop in opposite direction to the rotation of impeller.

  14. A numerical optimization on the vibroacoustics of a centrifugal fan volute

    Science.gov (United States)

    Lu, F. A.; Qi, D. T.; Wang, X. J.; Zhou, Z.; Zhou, H. H.

    2012-05-01

    A numerical optimization is presented to reduce the vibration and noise of a centrifugal fan volute. Minimal vibration was considered as the aim of the optimization, and the calculation of sound field induced by the vibration of the volute was only based on the final results of the optimization. After the three-dimensional unsteady flow simulation of a centrifugal fan, the parametric finite element model of the volute was created using the pressure fluctuations at blade passing frequency on the volute as external excitation forces. To validate the finite element model of the volute, natural frequencies and amplitudes of the normal velocities of the volute at blade passing frequency were measured. A good agreement was found between the numerical and the experimental results. Then, random method and first-order optimization method were applied in the optimization process. The numerical optimization of the volute was carried out using the local thickness of the volute as design variables and the quadratic sum of the nodal velocities as an objective function. Numerical optimization results show that the volute vibration is reduced by the optimization method. Finally, vibroacoustics of the volute before and after the optimization were calculated by direct boundary element method. The results show that the radiated power of the vibroacoustics of the volute is reduced significantly as well as the vibration of the volute after the optimization.This numerical optimization process provides a useful reference for vibroacoustic reduction of centrifugal compressors and centrifugal fans whose fluids should be kept strictly in a system without leakage.

  15. Defining the needs for gas centrifuge enrichment plants advanced safeguards

    Energy Technology Data Exchange (ETDEWEB)

    Boyer, Brian David [Los Alamos National Laboratory; Erpenbeck, Heather H [Los Alamos National Laboratory; Miller, Karen A [Los Alamos National Laboratory; Swinhoe, Martyn T [Los Alamos National Laboratory; Ianakiev, Kiril [Los Alamos National Laboratory; Marlow, Johnna B [Los Alamos National Laboratory

    2010-04-05

    Current safeguards approaches used by the International Atomic Energy Agency (IAEA) at gas centrifuge enrichment plants (GCEPs) need enhancement in order to verify declared low-enriched (LEU) production, detect undeclared LEU production and detect highly enriched uranium (HEU) production with adequate detection probability using nondestructive assay (NDA) techniques. At present inspectors use attended systems, systems needing the presence of an inspector for operation, during inspections to verify the mass and {sup 235}U enrichment of declared UF{sub 6} containers used in the process of enrichment at GCEPs. In verifying declared LEU production, the inspectors also take samples for off-site destructive assay (DA) which provide accurate data, with 0.1% to 0.5% measurement uncertainty, on the enrichment of the UF{sub 6} feed, tails, and product. However, taking samples of UF{sub 6} for off-site analysis is a much more labor and resource intensive exercise for the operator and inspector. Furthermore, the operator must ship the samples off-site to the IAEA laboratory which delays the timeliness of results and interruptions to the continuity of knowledge (CofK) of the samples during their storage and transit. This paper contains an analysis of possible improvements in unattended and attended NDA systems such as process monitoring and possible on-site analysis of DA samples that could reduce the uncertainty of the inspector's measurements and provide more effective and efficient IAEA GCEPs safeguards. We also introduce examples advanced safeguards systems that could be assembled for unattended operation.

  16. Comparative analysis of discrete exosome fractions obtained by differential centrifugation

    DEFF Research Database (Denmark)

    Jeppesen, Dennis Kjølhede; Hvam, Michael L; Primdahl-Bengtson, Bjarke;

    2014-01-01

    BACKGROUND: Cells release a mixture of extracellular vesicles, amongst these exosomes, that differ in size, density and composition. The standard isolation method for exosomes is centrifugation of fluid samples, typically at 100,000×g or above. Knowledge of the effect of discrete ultracentrifugat......BACKGROUND: Cells release a mixture of extracellular vesicles, amongst these exosomes, that differ in size, density and composition. The standard isolation method for exosomes is centrifugation of fluid samples, typically at 100,000×g or above. Knowledge of the effect of discrete...... ultracentrifugation speeds on the purification from different cell types, however, is limited. METHODS: We examined the effect of applying differential centrifugation g-forces ranging from 33,000×g to 200,000×g on exosome yield and purity, using 2 unrelated human cell lines, embryonic kidney HEK293 cells and bladder...... of phenol red and cleared by 200,000×g overnight centrifugation. The centrifugation tube fill level impacted the sedimentation efficacy. Comparative analysis by NTA, protein quantification, and detection of exosomal and contamination markers identified differences in vesicle size, concentration...

  17. Experience with the Sarns centrifugal pump in postcardiotomy ventricular failure.

    Science.gov (United States)

    Curtis, J J; Walls, J T; Schmaltz, R; Boley, T M; Nawarawong, W; Landreneau, R J

    1992-09-01

    The reported clinical use of the Sarns centrifugal pump (Sarns, Inc./3M, Ann Arbor, Mich.) as a cardiac assist device for postcardiotomy ventricular failure is limited. During a 25-month period ending November 1988, we used 40 Sarns centrifugal pumps as univentricular or biventricular cardiac assist devices in 27 patients who could not be weaned from cardiopulmonary bypass despite maximal pharmacologic and intraaortic balloon support. Eighteen men and nine women with a mean age of 60.4 years (28 to 83) required assistance. Left ventricular assist alone was used in 12 patients, right ventricular assist in 2, and biventricular assist in 13. The duration of assist ranged from 2 to 434 hours (median 45). Centrifugal assist was successful in weaning 100% of the patients. Ten of 27 patients (37%) improved hemodynamically, allowing removal of the device(s), and 5 of 27 (18.5%) survived hospitalization. Survival of patients requiring left ventricular assist only was 33.3% (4/12). Complications were common and included renal failure, hemorrhage, coagulopathy, ventricular arrhythmias, sepsis, cerebrovascular accident, and wound infection. During 3560 centrifugal pump hours, no pump thrombosis was observed. The Sarns centrifugal pump is an effective assist device when used to salvage patients who otherwise cannot be weaned from cardiopulmonary bypass. Statistical analysis of preoperative patient characteristics, operative risk factors, and postoperative complications failed to predict which patients would be weaned from cardiac assist or which would survive.

  18. Centrifuge modelling - migration of radionuclides from engineered trenches

    International Nuclear Information System (INIS)

    This report provides an overview of some centrifuge small-scale physical model tests and 1g experimental and theoretical work relating to the sub-surface migration of a model pollutant (sodium chloride) from a notional prototype surface landfill of width 25 metres and depth 3 metres cut into a 20 metre deep layer of nominally uniform soil overlying a more permeable base layer. An introduction is given to the application of geotechnical centrifuge modelling techniques to pollutant migration studies. Experiments performed at 1/100th scale using the Cambridge 10 metre diameter Geotechnical Beam Centrifuge simulating transport through silt over prototype time periods of around 35 years, are summarised. Comparisons of data with calculations using early versions of the POLLUTE and MIGRATE computer codes are presented. An experiment at 1/400th scale using the new Cambridge Geotechnical Drum Centrifuge, involving transport through clay over a prototype time period of around 1000 years, is described. Potential future uses of centrifuge modelling techniques to simulate long-term migration through more complex hydrological environments are also discussed. (author)

  19. A study on energy saving rate for variable speed condition of multistage centrifugal pump

    Science.gov (United States)

    Suh, Sang-Ho; Rakibuzzaman; Kim, Kyung-Wuk; Kim, Hyoung-Ho; Yoon, In Sik; Cho, Min-Tae

    2015-11-01

    Centrifugal pumps are being widely used in many industrial and commercial applications. Many of these pumps are being operated at constant speed but could provide energy savings through adjustable speed operations. The purpose of this study was to get the energy saving rates of the multistage centrifugal pump with variable speed conditions. For this investigation an experimental set up of variable flow and pressure system was made to get energy saving rates and numerical analyses are applied to validate the pump performance. The energy saving and therefore the cost saving depends on the specific duty cycle of which the machine operates. Duty cycle is the proportion of time during which a component, device and system is operated. The duty cycle segmented into different flow rates and weighting the average value for each segment by the interval time. The system was operated at 50% or less of the pump capacity. The input power of the system was carried out by pump characteristics curve of each operating point. The energy consumption was done by the product of specific duty cycle and the input power of the system for constant speed and variable speed drive operation. The total energy consumed for constant speed drive pump was 75,770 kW.hr and for variable speed drive pump was 31,700 kW.hr. The total energy saving of the system was 44,070 kW.hr or 58.16% annually. So, this paper suggests a method of implementing an energy saving on variable-flow and pressure system of the multistage centrifugal pump.

  20. Fault diagnosis of monoblock centrifugal pump using SVM

    Directory of Open Access Journals (Sweden)

    V. Muralidharan

    2014-09-01

    Full Text Available Monoblock centrifugal pumps are employed in variety of critical engineering applications. Continuous monitoring of such machine component becomes essential in order to reduce the unnecessary break downs. At the outset, vibration based approaches are widely used to carry out the condition monitoring tasks. Particularly fuzzy logic, support vector machine (SVM and artificial neural networks were employed for continuous monitoring and fault diagnosis. In the present study, the application of SVM algorithm in the field of fault diagnosis and condition monitoring is discussed. The continuous wavelet transforms were calculated for different families and at different levels. The computed transformation coefficients form the feature set for the classification of good and faulty conditions of the components of centrifugal pump. The classification accuracies of different continuous wavelet families at different levels were calculated and compared to find the best wavelet for the fault diagnosis of the monoblock centrifugal pump.

  1. Investigation of Surge Behavior in a Micro Centrifugal Compressor

    Institute of Scientific and Technical Information of China (English)

    Shimpei MIZUKI; Yuichiro ASAGA; Yushi ONO; Hoshio TSUJITA

    2006-01-01

    This paper reports the experimental and theoretical study of the surge occurred in prototyping an ultra micro centrifugal compressor. As the first step, the 10 times size model of an ultra micro centrifugal compressor having the 40 mm outer diameter was designed and manufactured. The detailed experimental investigations for the transient behavior of surge with several different values of B parameter were carried out. The experimental results during the surge were compared with those obtained by the non-linear lumped parameter theory in order to validate the effectiveness of the theoretical surge model for the micro centrifugal compressor. As a result, the quite different behavior of the surge appeared for the different values of B both in the experiment and in the analysis.

  2. Space Station Centrifuge: A Requirement for Life Science Research

    Science.gov (United States)

    Smith, Arthur H.; Fuller, Charles A.; Johnson, Catherine C.; Winget, Charles M.

    1992-01-01

    A centrifuge with the largest diameter that can be accommodated on Space Station Freedom is required to conduct life science research in the microgravity environment of space. (This was one of the findings of a group of life scientists convened at the University of California, Davis, by Ames Research Center.) The centrifuge will be used as a research tool to understand how gravity affects biological processes; to provide an on-orbit one-g control; and to assess the efficacy of using artificial gravity to counteract the deleterious biological effect of space flight. The rationale for the recommendation and examples of using ground-based centrifugation for animal and plant acceleration studies are presented. Included are four appendixes and an extensive bibliography of hypergravity studies.

  3. Centrifuge Techniques and Apparatus for Transport Experiments in Porous Media

    Energy Technology Data Exchange (ETDEWEB)

    Earl D. Mattson; Carl D. Paler; Robert W. Smith; Markus Flury

    2010-06-01

    This paper describes experimental approaches and apparatus that we have developed to study solute and colloid transport in porous media using Idaho National Laboratory's 2-m radius centrifuge. The ex-perimental techniques include water flux scaling with applied acceleration at the top of the column and sub-atmospheric pressure control at the column base, automation of data collection, and remote experimental con-trol over the internet. These apparatus include a constant displacement piston pump, a custom designed liquid fraction collector based on switching valve technology, and modified moisture monitoring equipment. Suc-cessful development of these experimental techniques and equipment is illustrated through application to transport of a conservative tracer through unsaturated sand column, with centrifugal acceleration up to 40 gs. Development of such experimental equipment that can withstand high accelerations enhances the centrifuge technique to conduct highly controlled unsaturated solute/colloid transport experiments and allows in-flight liquid sample collection of the effluent.

  4. Design Optimization of a Centrifugal Fan with Splitter Blades

    Science.gov (United States)

    Heo, Man-Woong; Kim, Jin-Hyuk; Kim, Kwang-Yong

    2015-05-01

    Multi-objective optimization of a centrifugal fan with additionally installed splitter blades was performed to simultaneously maximize the efficiency and pressure rise using three-dimensional Reynolds-averaged Navier-Stokes equations and hybrid multi-objective evolutionary algorithm. Two design variables defining the location of splitter, and the height ratio between inlet and outlet of impeller were selected for the optimization. In addition, the aerodynamic characteristics of the centrifugal fan were investigated with the variation of design variables in the design space. Latin hypercube sampling was used to select the training points, and response surface approximation models were constructed as surrogate models of the objective functions. With the optimization, both the efficiency and pressure rise of the centrifugal fan with splitter blades were improved considerably compared to the reference model.

  5. Design Method for Single-Blade Centrifugal Pump Impeller

    Science.gov (United States)

    Nishi, Yasuyuki; Fujiwara, Ryota; Fukutomi, Junichiro

    The sewage pumps are demanded a high pump efficiency and a performance in passing foreign bodies. Therefore, the impeller used by these usages requires the large passed particle size (minimum particle size in the pump). However, because conventional design method of pump impeller results in small impeller exit width, it is difficult to be applied to the design of single-blade centrifugal pump impeller which is used as a sewage pump. This paper proposes a design method for single-blade centrifugal pump impeller. As a result, the head curve of the impeller designed by the proposed design method satisfied design specifications, and pump efficiency was over 62% more than conventional single-blade centrifugal pump impeller. By comparing design values with CFD analysis values, the suction velocity ratio of the design parameter agreed well with each other, but the relative velocity ratio did not agree due to the influence of the backflow of the impeller entrance.

  6. Centrifugally activated bearing for high-speed rotating machinery

    Science.gov (United States)

    Post, Richard F.

    1994-01-01

    A centrifugally activated bearing is disclosed. The bearing includes an annular member that extends laterally and radially from a central axis. A rotating member that rotates about the central axis relative to the annular member is also included. The rotating member has an interior chamber that surrounds the central axis and in which the annular member is suspended. Furthermore, the interior chamber has a concave shape for retaining a lubricant therein while the rotating member is at rest and for retaining a lubricant therein while the rotating member is rotating. The concave shape is such that while the rotating member is rotating a centrifugal force causes a lubricant to be forced away from the central axis to form a cylindrical surface having an axis collinear with the central axis. This centrifugally displaced lubricant provides restoring forces to counteract lateral displacement during operation.

  7. "Centrifugal fragmentation" in the photodissociation of H2+ in intense laser fields

    CERN Document Server

    Fischer, Michael; Schmidt, Burkhard; Schmidt, Rüdiger

    2011-01-01

    By means of quantum-dynamical and classical trajectory calculations of H2+ photodissociation in strong laser fields, it is shown that for certain combinations of pulse durations and intensities the rotational dynamics can lead to centrifugal fragmentation. In that case, the photofragments exhibit characteristic angular distributions. The classical calculations provide a transparent physical picture of this mechanism which is also very well established in collisions between atomic nuclei or liquid droplets: non-rotating systems are stable, whereas rotating systems fragment due to the decrease of the fragmentation barrier with increasing angular momentum.

  8. Investigation of the jet-wake flow of a highly loaded centrifugal compressor impeller

    Science.gov (United States)

    Eckardt, D.

    1978-01-01

    Investigations, aimed at developing a better understanding of the complex flow field in high performance centrifugal compressors were performed. Newly developed measuring techniques for unsteady static and total pressures as well as flow directions, and a digital data analysis system for fluctuating signals were thoroughly tested. The loss-affected mixing process of the distorted impeller discharge flow was investigated in detail, in the absolute and relative system, at impeller tip speeds up to 380 m/s. A theoretical analysis proved good coincidence of the test results with the DEAN-SENOO theory, which was extended to compressible flows.

  9. Recent advances of annular centrifugal extractor for hot test of nuclear waste partitioning process

    Institute of Scientific and Technical Information of China (English)

    HeXiang-Ming; YanYu-Shun; 等

    1998-01-01

    Advances are being made in the design of the annular centrifugal extractor fornuclear fuel reprocessing extraction process studies.The extractors have been built and tested.Twelve stages of this extractor and 50 stages are used toimplement the TRPO process for the cleanup ofcommercial and defense nuclear waste liquids,respectively.Following advances are available:(1) simple way of assembly and disassembly between rotor part and housing part of extractor,ease of manipulator operation;(2)automatic sampling from housing of extractor in hot cell;(3) compact multi-stage housing system;(4) easy interstage link;(5) computer data acquisition and monitoring system of speed.

  10. Preliminary results of left heart bypass in pigs using a heparin-coated centrifugal pump.

    Science.gov (United States)

    Campanella, C; Cameron, E; Sinclair, C; Feilberg, V L; Hider, C; Prasad, S; Boulton, F; Lamb, D

    1991-08-01

    To assess the feasibility of left ventricular assist without systemic heparinization, we used a commercially available (Sarns 3M) centrifugal pump with tubing set and cannulas, all internally precoated for the purpose of this study with heparin, to bypass the left ventricle in 12 pigs for periods of either 1 or 3 hours. There was no significant activation of clotting and there was no sign of generalized embolization. However, on postmortem studies, 5 kidneys out of 22 examined showed signs of minimal thromboembolism. This experiment shows that artificial left ventricular assist, free of systemic heparinization but using heparin precoating, is feasible and safe, at least for a short period of time.

  11. Centrifuge modelling of a laterally cyclic loaded pile

    DEFF Research Database (Denmark)

    Klinkvort, Rasmus Tofte; Leth, Caspar Thrane; Hededal, Ole

    2010-01-01

    A total number of 9 static and 6 cyclic centrifuge tests on laterally loaded piles in very dense, dry sand was erformed. The prototype dimensions of the piles were 1 meter in diameter and penetration depths varying from 6 to 10 meters. The static tests were used to investigate the initial subgrade...... reaction modulus and as a reference for cyclic tests. For the cyclic tests the accumulation of deflections and the change in secant stiffness of the soil from repetitive loading were investigated. From all the tests carried out accumulations of deflections were seen. rom the centrifuge tests it was seen...

  12. Aspiration spiral-flow type centrifugal flotation machine

    Institute of Scientific and Technical Information of China (English)

    陈文义

    2002-01-01

    Aspiration spiral flow type centrifugal flotation machine takes full advantage of centrifugal force field and gravitational field, and strengthens flotation of coal slurry. As a new-type flotation machine of high efficiency, its key component is bubble generator. Which completes the process of ore pulp inflation and liberalization. The design, parameters and working principle of bubble generator provide the design of the same device in similar equipment with reference. The result of industrial operation shows that this machine is of such features as small occupational area, greater concentration ratio, high processing capacity, high efficiency and lower investment etc.

  13. Design Method for Channel Diffusers of Centrifugal Compressors

    Directory of Open Access Journals (Sweden)

    Mykola Kalinkevych

    2013-01-01

    Full Text Available The design method for channel diffusers of centrifugal compressors, which is based on the solving of the inverse problem of gas dynamics, is presented in the paper. The concept of the design is to provide high pressure recovery of the diffuser by assuming the preseparation condition of the boundary layer along one of the channel surfaces. The channel diffuser was designed with the use of developed method to replace the vaned diffuser of the centrifugal compressor model stage. The numerical simulation of the diffusers was implemented by means of CFD software. Obtained gas dynamic characteristics of the designed diffuser were compared to the base vaned diffuser of the compressor stage.

  14. On the characteristics of centrifugal-reciprocating machines. [cryogenic coolers

    Science.gov (United States)

    Higa, W. H.

    1980-01-01

    A method of compressing helium gas for cryogenic coolers is presented which uses centrifugal force to reduce the forces on the connecting rod and crankshaft in the usual reciprocating compressor. This is achieved by rotating the piston-cylinder assembly at a speed sufficient for the centrifugal force on the piston to overcome the compressional force due to the working fluid. The rotating assembly is dynamically braked in order to recharge the working space with fluid. The intake stroke consists of decelerating the rotating piston-cylinder assembly and the exhaust stroke consists of accelerating the assembly.

  15. Blade Crack Detection of Centrifugal Fan Using Adaptive Stochastic Resonance

    OpenAIRE

    Bingbing Hu; Bing Li

    2015-01-01

    Centrifugal fans are widely used in various industries as a kind of turbo machinery. Among the components of the centrifugal fan, the impeller is a key part because it is used to transform kinetic energy into pressure energy. Crack in impeller’s blades is one of the serious hidden dangers. It is important to detect the cracks in the blades as early as possible. Based on blade vibration signals, this research applies an adaptive stochastic resonance (ASR) method to diagnose crack fault in cent...

  16. The effect of gas fraction on centrifugal pump

    Science.gov (United States)

    Zhu, Z. T.; Wang, Y.; Zhao, L. F.; Ning, C.; Xie, S. F.; Liu, Z. C.

    2015-01-01

    In order to study the multiphase flow field in M125 centrifugal pump, three-dimensional modeling was used for internal flow through three-dimensional software Pro/E. Then based on SST turbulence model combining with Rayleigh-Plesset cavitation model, and structured grid to simulate the hydraulic characteristics of volute and impeller within different gas conditions. The velocity, pressure and gas volume fraction distributions of the interior flow field of volute and impeller were obtained and analyzed, which revealed the effect of gas fractions on the flow characteristic of the centrifugal pump.

  17. Flow in a Low Specific Speed Centrifugal Pump Using PIV

    OpenAIRE

    Cui Dai; Liang Dong

    2013-01-01

    The interflow plays important roles in centrifugal pump design. In order to study the effect of rotation and z-axis on internal flow, two-dimensional particle image velocimetry (PIV) measurements have been performed to measure the steady velocity field on three planes in all impeller passages of a low specific-speed centrifugal pump. The results show that the relative velocity flows in blade passages are obviously different in terms of the positions of the blade relative to the tongue. The in...

  18. Centrifugal compressor surge detecting method based on wavelet analysis of unsteady pressure fluctuations in typical stages

    Science.gov (United States)

    Izmaylov, R.; Lebedev, A.

    2015-08-01

    Centrifugal compressors are complex energy equipment. Automotive control and protection system should meet the requirements: of operation reliability and durability. In turbocompressors there are at least two dangerous areas: surge and rotating stall. Antisurge protecting systems usually use parametric or feature methods. As a rule industrial system are parametric. The main disadvantages of anti-surge parametric systems are difficulties in mass flow measurements in natural gas pipeline compressor. The principal idea of feature method is based on the experimental fact: as a rule just before the onset of surge rotating or precursor stall established in compressor. In this case the problem consists in detecting of unsteady pressure or velocity fluctuations characteristic signals. Wavelet analysis is the best method for detecting onset of rotating stall in spite of high level of spurious signals (rotating wakes, turbulence, etc.). This method is compatible with state of the art DSP systems of industrial control. Examples of wavelet analysis application for detecting onset of rotating stall in typical stages centrifugal compressor are presented. Experimental investigations include unsteady pressure measurement and sophisticated data acquisition system. Wavelet transforms used biorthogonal wavelets in Mathlab systems.

  19. Hydrodynamic and mass transfer studies in 50 mm centrifugal extractor

    International Nuclear Information System (INIS)

    Solvent extraction is promising unit operation in reprocessing of closed nuclear fuel cycle. Unlike thermal reactor in fast reactor spent fuel reprocessing criticality and radiation damage problems are severe. This leads to the degradation of solvent and increase its inventory. To address these challenges solvent extraction equipment with small hold up and fast separation is required. Hence, centrifugal extractors are inevitable. In mass transfer studies extraction operation was carried at constant rotor speed 3000 rpm and constant flow ratio of 1 for 30%TBP and nearly 4N HNO3 system by varying total throughput from 50 ml/min to 1500 ml/min. In mass transfer studies stripping operation was carried at constant rotor speed 3000 rpm and constant flow rate of 500 ml/min for loaded TBP and slightly acidified RO water system by varying A/O flow ratio from 0.1 to 10. Mass transfer efficiency for both the cases was found to be nearly 100%. In mass transfer studies stripping operation was carried at constant total throughput of 500 ml/min and constant A/O flow ratio of 1 for rotor speeds 1500, 2000, 3000 and 4000 rpm. Mass transfer efficiency was found to slightly dependent on rotor speed. In hydrodynamics flooding limit was found under no mass transfer conditions for A/O flow ratios from 0.1 to 10 at 2500, 3000 and 3500 rpm. Maximum possible throughput was found to be ≅ 110 lph. Modeling of flooding behavior was found to be difficult

  20. Active control of surge in centrifugal compressors using magnetic thrust bearing actuation

    Science.gov (United States)

    Sanadgol, Dorsa

    This research presents a new method for active surge control in centrifugal compressors with unshrouded impellers using a magnetic thrust bearing to modulate the impeller tip clearance. Magnetic bearings offer the potential for active control of flow instabilities. This capability is highly dependent on the sensitivity of the compressor characteristics to blade tip clearance. If the position of the shaft can be actuated with sufficient authority and speed, the induced pressure modulation makes control of surge promising. The active nature of the magnetic bearing system makes the real-time static and dynamic positioning of the rotor and therefore modulation of the impeller tip clearance possible. A theoretical model is first established that describes the sensitivity of the centrifugal compressor characteristic curve to tip clearance variations induced by axial motion of the rotor. Results from simulation of the nonlinear model for a single stage high-speed centrifugal compressor show that using the proposed control method, mass flow and pressure oscillations associated with compressor surge are quickly suppressed with acceptable tip clearance excursions, typically less than 20% of the available clearance. It is shown that it is possible to produce adequate axial excursions in the clearance between the impeller blades and the adjacent stationary shroud using a magnetic thrust bearing with practical levels of drive voltage. This surge control method would allow centrifugal compressors to reliably and safely operate with a wider range than is currently done in the field. The principal advantage of the proposed approach over conventional surge control methods lies in that, in machines already equipped with magnetic bearing, the method can potentially be implemented by simply modifying controller software. This dispenses with the need to introduce additional hardware, permitting adaptation of existing machinery at virtually no cost. In addition, since the controller is

  1. The human response to artificial gravity in a weightless environment: Results from the Neurolab centrifugation experiments

    Science.gov (United States)

    Moore, Steven T.; Clément, Gilles; Raphan, Theodore; Curthoys, Ian; Koizuka, Izumi; Cohen, Bernard

    2000-01-01

    On Earth, afferent otolith activity encodes head tilt with respect to gravity, as well as head linear acceleration. The vector sum of head acceleration and gravity, termed gravito-inertial acceleration (GIA), is used by the vestibular system to generate the perception of vertical, ocular counter-rolling (OCR), and vertical or roll components of nystagmus, which orient the axis of eye velocity towards alignment with the GIA. Head tilt is not sensed by the otoliths in microgravity, but the otoliths are still activated by translation. It has therefore been proposed that the brain reinterprets tilt-related otolith information as translation during space flight. During the 1998 Neurolab mission, 4 astronauts were exposed to inter-aural (IA) and body vertical (Z-axis) centripetal accelerations of 0.5 and 1-g by rotation in an off-axis centrifuge. During rotation, binocular 3D eye movements were measured using a video technique with the subject in darkness and while viewing an optokinetic stimulus. On Earth, 1-g centrifugation tilts the GIA 45° with respect to the head, and pre-flight perception of roll tilt was 35°. By flight day 5, all astronauts perceived ~90° of roll tilt in response to a constant 1-g IA linear acceleration. This tilt angle was under-reported early in flight, and over-estimated on return to Earth, possibly due to adaptation of otolith and/or somatosensory function during transition to the new gravitational states. Tilt perception was proportionally lower during 0.5-g centrifugation, both pre-flight (20°) and in-flight (46°). Similar results were obtained for pitch tilt perception during Z-axis centrifugation. The magnitude of OCR in response to the GIA during IA centrifugation was unchanged in microgravity, and was proportional to the centripetal acceleration. This suggests that both OCR and roll tilt perception are strongly dependent on the magnitude of IA linear acceleration, as in microgravity there is no body vertical (Z-axis) linear

  2. Novel design for centrifugal counter-current chromatography: VI. Ellipsoid column.

    Science.gov (United States)

    Gu, Dongyu; Yang, Yi; Xin, Xuelei; Aisa, Haji Akber; Ito, Yoichiro

    2015-01-01

    A novel ellipsoid column was designed for centrifugal counter-current chromatography. Performance of the ellipsoid column with a capacity of 3.4 mL was examined with three different solvent systems composed of 1-butanol-acetic acid-water (4:1:5, v/v) (BAW), hexane-ethyl acetate-methanol-0.1 M HCl (1:1:1:1, v/v) (HEMH), and 12.5% (w/w) PEG1000 and 12.5% (w/w) dibasic potassium phosphate in water (PEG-DPP) each with suitable test samples. In dipeptide separation with BAW system, both stationary phase retention (Sf) and peak resolution (Rs) of the ellipsoid column were much higher at 0° column angle (column axis parallel to the centrifugal force) than at 90° column angle (column axis perpendicular to the centrifugal force), where elution with the lower phase at a low flow rate produced the best separation yielding Rs at 2.02 with 27.8% Sf at a flow rate of 0.07 ml/min. In the DNP-amino acid separation with HEMW system, the best results were obtained at a flow rate of 0.05 ml/min with 31.6% Sf yielding high Rs values at 2.16 between DNP-DL-glu and DNP-β-ala peaks and 1.81 between DNP-β-ala and DNP-L-ala peaks. In protein separation with PEG-DPP system, lysozyme and myolobin were resolved at Rs of 1.08 at a flow rate of 0.03 ml/min with 38.9% Sf. Most of those Rs values exceed those obtained from the figure-8 column under similar experimental conditions previously reported.

  3. Mechanism of Gas Intrusion into Molten Metal during Horizontal Centrifugal Casting

    Institute of Scientific and Technical Information of China (English)

    NI Feng; ZHANG Xhan-ling; YANG Di-xin; BI Xiao-qin; ZHANG Yong-zhen

    2004-01-01

    A mechanism of gas intrusion into molten metal during horizontal centrifugal casting was introduced .Based upon this concept, a special pouring method was suggested ,which can effectively prevent the pinhole defects in horizontal centrifugal castings.

  4. Effects of centrifugation stress on pituitary-gonadal function in male rats

    Science.gov (United States)

    Gray, G. D.; Smith, E. R.; Damassa, D. A.; Davidson, J. M.

    1980-01-01

    The effects of centrifugation for various lengths of time on circulating levels of luteinizing hormone (LH) and testosterone in male rats were investigated. In a chronic 52-day experiment, centrifugation at 4.1 G significantly reduced LH and testosterone levels for the entire period. Centrifugation at 2.3 G had less effect inasmuch as LH levels were not significantly decreased and testosterone levels were significantly reduced only during the first few days of centrifugation. In more acute experiments, centrifugation at 4.1 G for 4 h resulted in reduced testosterone levels, whereas centrifugation for 15 min did not significantly alter the hormone levels. These results indicate that centrifugation can decrease circulating LH and testosterone levels if the gravitational force is of sufficient magnitude and is maintained for a period of hours. Chronic centrifugation may also inhibit the acute excitatory response of LH to handling and ether stress.

  5. Design of On-line Monitoring System for Running Parameter of Large Centrifugal Compressor Unit%大型离心式压缩机组运行参数在线监测系统的设计

    Institute of Scientific and Technical Information of China (English)

    曲延滨; 腾飞; 赵丽

    2001-01-01

    介绍了Schlumberg公司的分散式数据转换器IMP及在监测系统中的应用。给出了IMP在大型空气压缩机组运行参数在线监测系统中的应用实例。%This paper discusses the IMP(Isolated Measurement Pods)of Schlumberg Co.and its application in monitoring system.A instance of IMP which is used in on-line monitoring system for running parameter of air compressor unit is also shown.

  6. Dynamic actuator for Soil-Structure Interaction physical modelling in centrifuge

    OpenAIRE

    CABRERA, Miguel; Caicedo, Bernardo; THOREL, Luc

    2014-01-01

    Dynamic interactions in centrifuge modelling are often induced with external or not controlled sources. This paper presents a method to study Soil-Structure Interaction in centrifuge, with the use of a dynamic actuator developed for centrifuge testing. The dynamic actuator is employed into the model giving the possibility to test the dynamic response of a wind turbine structure, without any additional supporting accessory. The centrifuge soil model was instrumented in order to measure the wav...

  7. Effect of inner structure of centrifugal separator on particle classification performance

    OpenAIRE

    Yamamoto, Tetsuya; Watanabe, Natsuko; Fukui, Kunihiro; Yoshida, Hideto

    2009-01-01

    This study investigated the effects of the inner structure of a centrifugal separator on particle classification performance. The typical inner structure of centrifugal separators is as follows: a blade, which consists of two orthogonal plates. is inserted into the centrifugal separator to create rigid fluid and particle rotations. The results of the present study demonstrate that centrifugal separator performance was significantly improved by attachment of a cylinder to the center of a conve...

  8. Thermal hydrodynamic analysis of a countercurrent gas centrifuge

    International Nuclear Information System (INIS)

    The influence of the thermal countercurrent on the separative performance of countercurrent centrifuges is treated in this work. The methodology used consists in modeling the gas flow inside the rotor under thermal boundary conditions supplied by the structural thermal model. The gas flow model, also called hydrodynamical model, is based on the Finite Volume Method for cylindrical geometry with azimuthal symmetry. The structural thermal model is based on the Nodal Method and take into account simultaneously, the conduction convection and radiation phenomena. The procedure adopted for this study consisted in the definition of the operational and geometric conditions of a centrifuge which was used as a pattern to the accomplished analysis. This configuration, called 'Standard Centrifuge', was used for the accomplishment of several simulations where the importance of the realistic boundary thermal conditions for the numerical evaluation of the centrifuge separative capacity was evidenced. A selective alteration for the optical properties based on simple engineering procedures was proposed. An improvement of 5% was obtained with this alteration. (author)

  9. Centrifuge modeling of LNAPL transport in partially saturated sand

    NARCIS (Netherlands)

    Esposito, G.; Allersma, H.G.B.; Selvadurai, A.P.S.

    1999-01-01

    Model tests were performed at the Geotechnical Centrifuge Facility of Delft University of Technology, The Netherlands, to examine the mechanics of light nonaqueous phase liquid (LNAPL) movement in a partially saturated porous granular medium. The experiment simulated a 2D spill of LNAPL in an unsatu

  10. Centrifugal impeller operating at a very low temperature

    International Nuclear Information System (INIS)

    Several compression stages working at very low temperatures (approximately= 4 K) and low pressures (approximately= 10 mb) have been calculated, assembled and tested. Good thermodynamic efficiencies (approximately= 0,55) and compression ratios (approximately= 3) are obtained. A compression stage is constituted by a centrifugal impeller surrounded by a static diffuser

  11. Centrifugal Model Tests on Railway Embankments of Expansive Soils

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    Based on the centrifugal model tests on railway embankments of expansive soil in Nanning-Kunming railway,the author studied several embankments under different physical conditions. The stress and strain states and settlement of the embankments were analyzed, and the obtained results can be used as a reference to field construction.

  12. Centrifuge modelling of rigid piles in soft clay

    DEFF Research Database (Denmark)

    Klinkvort, R.T.; Poder, M.; Truong, P.;

    2016-01-01

    of this study is to employ centrifuge modelling in order to derive experimental p-y curves for rigid piles embedded in over-consolidated soft clay. A kaolin clay sample was prepared and pre-consolidated by applying a constant pressure at the soil surface, while different over-consolidation ratios were achieved...

  13. Model Based Fault Detection in a Centrifugal Pump Application

    DEFF Research Database (Denmark)

    Kallesøe, Carsten; Cocquempot, Vincent; Izadi-Zamanabadi, Roozbeh

    2006-01-01

    A model based approach for fault detection in a centrifugal pump, driven by an induction motor, is proposed in this paper. The fault detection algorithm is derived using a combination of structural analysis, observer design and Analytical Redundancy Relation (ARR) design. Structural considerations...

  14. Liquid egg white pasteurization using a centrifugal UV irradiator

    Science.gov (United States)

    Studies are lacking on UV nonthermal pasteurization of liquid egg white (LEW). The objective of this study was to inactivate Escherichia coli using a UV irradiator that centrifugally formed a thin film of LEW on the inside of a rotating cylinder. The LEW was inoculated with E. coli K12 to approximat...

  15. DEMONSTRATION BULLETIN: THE PLASMA CENTRIFUGAL FURNACE RETECH, INC.

    Science.gov (United States)

    The plasma centrifugal furnace is a thermal technology which uses the heat generated from a plasma torch to decontaminate metal and organic contaminated waste. This is accomplished by melting metal-bearing solids and, in the process, thermally destroying organic contaminants. The...

  16. Pasteurization of grapefruit juice using a centrifugal ultraviolet light irradiator

    Science.gov (United States)

    The pharmaceutical industry uses UV irradiators to inactivate viruses in liquids without heat. The penetration depth of UV in some liquids, such as serum plasma, can be short. To overcome this, very thin films may be produced by centrifugal force, small diameter tubing, or other means. Many liquid f...

  17. Latex micro-balloon pumping in centrifugal microfluidic platforms.

    Science.gov (United States)

    Aeinehvand, Mohammad Mahdi; Ibrahim, Fatimah; Harun, Sulaiman Wadi; Al-Faqheri, Wisam; Thio, Tzer Hwai Gilbert; Kazemzadeh, Amin; Madou, Marc

    2014-03-01

    Centrifugal microfluidic platforms have emerged as point-of-care diagnostic tools. However, the unidirectional nature of the centrifugal force limits the available space for multi-step processes on a single microfluidic disc. To overcome this limitation, a passive pneumatic pumping method actuated at high rotational speeds has been previously proposed to pump liquid against the centrifugal force. In this paper, a novel micro-balloon pumping method that relies on elastic energy stored in a latex membrane is introduced. It operates at low rotational speeds and pumps a larger volume of liquid towards the centre of the disc. Two different micro-balloon pumping mechanisms have been designed to study the pump performance at a range of rotational frequencies from 0 to 1500 rpm. The behaviour of the micro-balloon pump on the centrifugal microfluidic platforms has been theoretically analysed and compared with the experimental data. The experimental data show that the developed pumping method dramatically decreases the required rotational speed to pump liquid compared to the previously developed pneumatic pumping methods. It also shows that within a range of rotational speed, a desirable volume of liquid can be stored and pumped by adjusting the size of the micro-balloon.

  18. Pasteurization of Grapefruit Juice using a Centrifugal Ultraviolet Light Device

    Science.gov (United States)

    The pharmaceutical industry uses UV devices to nonthermally inactivate viruses in liquids. To overcome the low penetration depth of UV in some liquids, such as serum plasma, thin films are formed by centrifugal force. Liquid foods also have low UV penetration depths. Studies are lacking on nontherma...

  19. Pressure Pulsation Signal Analysis for Centrifugal Compressor Blade Crack Determination

    Directory of Open Access Journals (Sweden)

    Hongkun Li

    2014-01-01

    Full Text Available Blade is a key piece of component for centrifugal compressor. But blade crack could usually occur as blade suffers from the effect of centrifugal forces, gas pressure, friction force, and so on. It could lead to blade failure and centrifugal compressor closing down. Therefore, it is important for blade crack early warning. It is difficult to determine blade crack as the information is weak. In this research, a pressure pulsation (PP sensor installed in vicinity to the crack area is used to determine blade crack according to blade vibration transfer process analysis. As it cannot show the blade crack information clearly, signal analysis and empirical mode decomposition (EMD are investigated for feature extraction and early warning. Firstly, signal filter is carried on PP signal around blade passing frequency (BPF based on working process analysis. Then, envelope analysis is carried on to filter the BPF. In the end, EMD is carried on to determine the characteristic frequency (CF for blade crack. Dynamic strain sensor is installed on the blade to determine the crack CF. Simulation and experimental investigation are carried on to verify the effectiveness of this method. The results show that this method can be helpful for blade crack classification for centrifugal compressors.

  20. Centrifugal pumping of gas-liquid mixtures: a mechanistic approach

    Energy Technology Data Exchange (ETDEWEB)

    Estevam, Valdir [PETROBRAS, Rio de Janeiro, RJ (Brazil); Franca, Fernando A. [Universidade Estadual de Campinas, SP (Brazil); Alhanati, Francisco J.S. [C-Fer Technologies, Edmonton, Alberta (Canada)

    2004-07-01

    Centrifugal pumps are known to show a 'surging' behavior at certain conditions of free gas and liquid flow rate at the intake. In the 'surging region' on a pump characteristic curve, the head generated is significantly lower than if the pump were handling a gas-liquid homogeneous mixture. The surging happens, as one shows in this paper, due to the existence of a gas pocket, referred as 'elongated bubble', at the pump impeller inlet region. Therefore, to be able to predict the performance of centrifugal pumps under two-phase conditions, one has to disclose and model the mechanisms that set existence of the elongated bubble at the impeller inlet, besides calculating its length inside the impeller. This paper reports on the results of experimental and mechanistic modelling work conducted with the objective of better predicting the gas-liquid performance of centrifugal pumps under all range of conditions, including those characterized by 'surging'. The focus was on small diameter centrifugal pumps used to produce oil wells. A mechanistic two-fluid model devised to calculate the head generated by the pump was developed. The predictions of the model show good agreement with data collected for this study, and with data recently collected by other research organizations. (author)

  1. The cavitation behavior with short length blades in centrifugal pump

    Energy Technology Data Exchange (ETDEWEB)

    Thai, Quangnha; Lee, Chang Jin [Konkuk University, Seoul (Korea, Republic of)

    2010-10-15

    A CFD code with 2-D cascade model was developed to predict the cavitation behavior around the impeller blades of impeller in a centrifugal pump. The governing equations are the two-phase Reynolds Averaged Navier-Stokes equations in a homogeneous form in which both liquid and vapor phases are treated as incompressible fluid. To close the model, a standard k-{epsilon} turbulence model is introduced. And the mass transfer rates between liquid and vapor phases are implemented as well. The validations are carried out by comparing with reference data in impeller of a centrifugal pump impeller. The cavitation characteristics of current centrifugal pumps is tested at an on design point (V=8 m/s) and two off-design points (V=20 m/s and V=30 m/s), respectively. The criteria of cavitation and flow instability around blades are presented. The results show that the current centrifugal pump can safely operate without cavitation at on-design point. Also, the simulation shows cavitation develops inhomogeneously among the blades at off-design points. Moreover, the effects of additional blades in the impeller are studied as well. From the numerical results, it is expected that a half-length blade is the optimum configuration as additional blades in cavitation point of view

  2. Prediction of performance of centrifugal pumps during starts under pressure

    Science.gov (United States)

    Rostafinski, W.

    1969-01-01

    Method which calculates start-up characteristics of centrifugal pumps reveals a capacity to predict pressure drop characteristics of pumps with vaned diffusers. Calculations are based on pump geometry, design-point flow, speed, and pressure rise, and the pump characteristic within range of approximately ten percent of the design-point flow.

  3. Measurements of the rotordynamic shroud forces for centrifugal pumps

    Science.gov (United States)

    Guinzburg, A.; Brennen, C. E.; Acosta, A. J.; Caughey, T. K.

    1990-01-01

    An experiment was designed to measure the rotordynamic shroud forces on a centrifugal pump impeller. The measurements were done for various whirl/impeller speed ratios and for different flow rates. A destabilizing tangential force was measured for small positive whirl ratios and this force decreased with increasing flow rate.

  4. Synthesis and Analytical Centrifugation of Magnetic Model Colloids

    NARCIS (Netherlands)

    Luigjes, B.

    2012-01-01

    This thesis is a study of the preparation and thermodynamic properties of magnetic colloids. First, two types of magnetic model colloids are investigated: composite colloids and single-domain nanoparticles. Thermodynamics of magnetic colloids is studied using analytical centrifugation, including a s

  5. 21 CFR 864.9275 - Blood bank centrifuge for in vitro diagnostic use.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Blood bank centrifuge for in vitro diagnostic use... Manufacture Blood and Blood Products § 864.9275 Blood bank centrifuge for in vitro diagnostic use. (a) Identification. A blood bank centrifuge for in vitro diagnostic use is a device used only to separate blood...

  6. Enhancement of invasiveness of Yersinia enterocolitica and Escherichia coli in HEp-2 cells by centrifugation.

    OpenAIRE

    Vesikari, T; Bromirska, J; Mäki, M

    1982-01-01

    Centrifugation enhanced the infectivity of invasive Escherichia coli and Yersinia enterocolitica for HEp-2 cells. Noninvasive bacteria were not endocytosed after centrifugation. The centrifugation procedure may increase the sensitivity of testing for bacterial invasiveness in cell culture without causing false-positive results.

  7. Experimental Investigation on Characteristics of Flow Instabilities in Centrifugal Pump Impeller under Part-Load Conditions

    OpenAIRE

    Denghao Wu; Yun Ren; Houlin Liu; Jiegang Mu; Lanfang Jiang

    2014-01-01

    This paper presents an experimental investigation of large-scale flow-field instabilities in a centrifugal pump impeller of low specific speed. Measurements of pump hydraulic performance and flow-field in the impeller passages were made with a hydraulic test rig and a Particle Image Velocimetry (PIV) system separately. Analyses of Q-H data and flow structures in the impeller passages were performed. Results showed that an unstable area existed in the range from 0.1QBEP to 0.6QBEP and had a cl...

  8. Vacuum Infiltration-Centrifugation Method for Apoplastic Protein Extraction in Grapevine.

    Science.gov (United States)

    Delaunois, Bertrand; Baillieul, Fabienne; Clément, Christophe; Jeandet, Philippe; Cordelier, Sylvain

    2016-01-01

    The apoplastic fluid moving in the extracellular space external to the plasma membrane provides a means of delivering molecules and facilitates intercellular communications. However, the apoplastic fluid extraction from in planta systems remains challenging and this is particularly true for grapevine (Vitis vinifera L.), a worldwide-cultivated fruit plant. Here, we describe an optimized vacuum-infiltration-centrifugation method to extract soluble proteins from apoplastic fluid of grapevine leaves. This optimized method allows recovering of the grapevine apoplastic soluble proteins suitable for mono- and bi-dimensional gel electrophoresis for further proteomic analysis in order to elucidate their physiological functions. PMID:27665564

  9. Experimental analysis of the inertial soil-pile interaction in the centrifuge

    OpenAIRE

    CHENAF, N; CHAZELAS, JL; Escoffier, S.

    2006-01-01

    The soil-pile dynamic interaction is studied through centrifuge tests. In this paper, we focus on the inertial effect as a first step to knowledge the seismic behaviour of the soil-pile system. A single shock test, applied at the head of a flexible single pile, is used to simulate an impact on bridge piers ; successive shocks are also used to simulate boat impacts on harbour facilities. To improve the understanding of the inertial soil-pile interaction, a comparison of pile response to both l...

  10. Comparative analysis of discrete exosome fractions obtained by differential centrifugation

    Directory of Open Access Journals (Sweden)

    Dennis K. Jeppesen

    2014-11-01

    Full Text Available Background: Cells release a mixture of extracellular vesicles, amongst these exosomes, that differ in size, density and composition. The standard isolation method for exosomes is centrifugation of fluid samples, typically at 100,000×g or above. Knowledge of the effect of discrete ultracentrifugation speeds on the purification from different cell types, however, is limited. Methods: We examined the effect of applying differential centrifugation g-forces ranging from 33,000×g to 200,000×g on exosome yield and purity, using 2 unrelated human cell lines, embryonic kidney HEK293 cells and bladder carcinoma FL3 cells. The fractions were evaluated by nanoparticle tracking analysis (NTA, total protein quantification and immunoblotting for CD81, TSG101, syntenin, VDAC1 and calreticulin. Results: NTA revealed the lowest background particle count in Dulbecco's Modified Eagle's Medium media devoid of phenol red and cleared by 200,000×g overnight centrifugation. The centrifugation tube fill level impacted the sedimentation efficacy. Comparative analysis by NTA, protein quantification, and detection of exosomal and contamination markers identified differences in vesicle size, concentration and composition of the obtained fractions. In addition, HEK293 and FL3 vesicles displayed marked differences in sedimentation characteristics. Exosomes were pelleted already at 33,000×g, a g-force which also removed most contaminating microsomes. Optimal vesicle-to-protein yield was obtained at 67,000×g for HEK293 cells but 100,000×g for FL3 cells. Relative expression of exosomal markers (TSG101, CD81, syntenin suggested presence of exosome subpopulations with variable sedimentation characteristics. Conclusions: Specific g-force/k factor usage during differential centrifugation greatly influences the purity and yield of exosomes. The vesicle sedimentation profile differed between the 2 cell lines.

  11. A comparison of moving-boundary and finite-volume formulations for transients in centrifugal chillers

    Energy Technology Data Exchange (ETDEWEB)

    Bendapudi, Satyam [United Technologies Research Center, East Hartford, CT (United States); Braun, James E.; Groll, Eckhard A. [School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907 (United States)

    2008-12-15

    Dynamic models of vapor compression systems are useful tools in developing feedback controllers and are gaining increasing attention in recent years. The dominant dynamics are typically those of the evaporator and condenser, which are difficult to model. Accuracy and execution speed of system models therefore are highly dependent on the modeling approach of the heat exchangers. The two common approaches are the finite-volume (FV) and the moving-boundary (MB) methods. Both have been used successfully and reported in the literature, but there is little discussion presented for either choice. This paper presents the development and comparative study of shell-and-tube heat exchanger dynamic models using both the FV and the MB approaches. Detailed model formulations are provided and stability is demonstrated as components and within a complete centrifugal chiller system model. The system models are validated using data from a 300 kW R134a centrifugal chiller test stand. The FV formulation is found to be more robust through start-up and all load-change transients, but executes slower. The moving-boundary method can handle all load-change transients but start-up stability is more sensitive to compressor and expansion valve formulations. The moving-boundary formulation also executes about three times faster than the finite-volume while maintaining nearly identical accuracy. With the homogenous two-phase assumption, charge prediction is seen to be less accurate in the moving-boundary approach. (author)

  12. Modeling for control of centrifugal compressors

    OpenAIRE

    Leufvén, Oskar

    2013-01-01

    Downsizing and turbocharging of engines provide a way to meet increasing demands for efficiency and performance in the automotive industry. An engine design is a result of compromises, e.g. the selection of charging system, and the trend is to reduce these compromises by increasing system complexity. Models have come to play a central role to handle this rise in complexity, and are used for simulation, system optimization and control synthesis. The models should describe the entire operating ...

  13. Experimental study on control model of centrifugal pump variable-pressure water supply system%离心泵变压供水系统控制模型辨识的试验研究

    Institute of Scientific and Technical Information of China (English)

    汤跃; 张新鹏; 黄志攀; 成军

    2012-01-01

    Variable-pressure water supply is considered to be a good operation mode to save energy. But lacking enough study on the control model results in pressure fluctuation at user side, which will restrict variable-pressure water supply for application and popularization. To improve the control quality, a step response experiment rig of water-supply system was set up based on virtual instrument and frequency converter. A Lab VIEW test program was compiled to carry out the step response experiment at different openings of valve. And then process models were constructed with system identification toolbox of Matlab according to experiment data. Contrasting the theoretical and experimental models, variations among different processes were analyzed from vertical and horizontal aspects. The results showed that the variable-pressure operation had a similar variation trend in structure and parameters, and it also had more obvious inertia, time varying and hysteretic nature. So the transient state performance of the variable-pressure water supply system should be considered for design of variable-parameter controller with PID.%离心泵变压供水被认为是一种节能供水模式,但由于对其控制模型的研究不够深入,在水泵变工况运行时常常造成用户端水压不稳,推广应用受到很大限制.为提高变压运行控制系统性能,利用变频器、虚拟仪器搭建离心泵供水系统试验台,编制LabView测控程序,进行变工况下的变压和恒压模型辨识试验.根据各响应过程,通过MATLAB系统辨识工具箱建立过程模型与理论模型比较,并对比分析相同阀门开度下和不同阀门开度下变压与恒压过程控制模型的参数和结构变化.结果表明随着离心泵工况改变,变压供水控制模型是定结构的带延迟二阶模型,参数具有较大幅度的变化,其惯性、时变和时滞特性比恒压供水更大,建议针对系统暂态性能改善设计具有PID特性的变参数控制器.

  14. The enhanced ASDEX Upgrade pellet centrifuge launcher

    Science.gov (United States)

    Plöckl, B.; Lang, P. T.

    2013-10-01

    Pellets played an important role in the program of ASDEX Upgrade serving both for investigations on efficient particle fuelling and high density scenarios but also for pioneering work on Edge Localised Mode (ELM) pacing and mitigation. Initially designed for launching fuelling pellets from the magnetic low field side, the system was converted already some time ago to inject pellets from the magnetic high field side as much higher fuelling efficiency was found using this configuration. In operation for more than 20 years, the pellet launching system had to undergo a major revision and upgrading, in particular of its control system. Furthermore, the control system installed adjacent to the launcher had to be transferred to a more distant location enforcing a complete galvanic separation from torus potential and a fully remote control solution. Changing from a hybrid system consisting of PLC S5/S7 and some hard wired relay control to a state of the art PLC system allowed the introduction of several new operational options enabling more flexibility in the pellet experiments. This article describes the new system architecture of control hardware and software, the operating procedure, and the extended operational window. First successful applications for ELM pacing and triggering studies are presented as well as utilization for the development of high density scenarios.

  15. A study of the Coriolis effect on the fluid flow profile in a centrifugal bioreactor.

    Science.gov (United States)

    Detzel, Christopher J; Thorson, Michael R; Van Wie, Bernard J; Ivory, Cornelius F

    2009-01-01

    Increasing demand for tissues, proteins, and antibodies derived from cell culture is necessitating the development and implementation of high cell density bioreactors. A system for studying high density culture is the centrifugal bioreactor (CCBR), which retains cells by increasing settling velocities through system rotation, thereby eliminating diffusional limitations associated with mechanical cell retention devices. This article focuses on the fluid mechanics of the CCBR system by considering Coriolis effects. Such considerations for centrifugal bioprocessing have heretofore been ignored; therefore, a simpler analysis of an empty chamber will be performed. Comparisons are made between numerical simulations and bromophenol blue dye injection experiments. For the non-rotating bioreactor with an inlet velocity of 4.3 cm/s, both the numerical and experimental results show the formation of a teardrop shaped plume of dye following streamlines through the reactor. However, as the reactor is rotated, the simulation predicts the development of vortices and a flow profile dominated by Coriolis forces resulting in the majority of flow up the leading wall of the reactor as dye initially enters the chamber, results are confirmed by experimental observations. As the reactor continues to fill with dye, the simulation predicts dye movement up both walls while experimental observations show the reactor fills with dye from the exit to the inlet. Differences between the simulation and experimental observations can be explained by excessive diffusion required for simulation convergence, and a slight density difference between dyed and un-dyed solutions. Implications of the results on practical bioreactor use are also discussed.

  16. Quality evaluation of energy consumed in flow regulation method by speed variation in centrifugal pumps

    Science.gov (United States)

    Morales, S.; Culman, M.; Acevedo, C.; Rey, C.

    2014-06-01

    Nowadays, energy efficiency and the Electric Power Quality are two inseparable issues in the evaluation of three-phase induction motors, framed within the program of Rational and Efficient Use of Energy (RUE).The use of efficient energy saving devices has been increasing significantly in RUE programs, for example the use of variable frequency drives (VFD) in pumping systems.The overall objective of the project was to evaluate the impact on power quality and energy efficiency in a centrifugal pump driven by an induction three-phase motor, using the flow control method of speed variation by VFD. The fundamental purpose was to test the opinions continuously heard about the use of flow control methods in centrifugal pumps, analyzing the advantages and disadvantages that have been formulated deliberately in order to offer support to the industry in taking correct decisions. The VFD changes the speed of the motor-pump system increasing efficiency compared to the classical methods of regulation. However, the VFD originates conditions that degrade the quality of the electric power supplied to the system and therefore its efficiency, due to the nonlinearity and presence of harmonic currents. It was possible to analyze the power quality, ensuring that the information that comes to the industry is generally biased.

  17. Environmental and centrifugal factors influencing the visco-elastic properties of oral biofilms in vitro.

    Science.gov (United States)

    Peterson, Brandon W; Busscher, Henk J; Sharma, Prashant K; van der Mei, Henny C

    2012-01-01

    Centrifugal compaction causes changes in the surface properties of bacterial cells. It has been shown previously that the surface properties of planktonic cells change with increasing centrifugal compaction. This study aimed to analyze the influences of centrifugal compaction and environmental conditions on the visco-elastic properties of oral biofilms. Biofilms were grown out of a layer of initially adhering streptococci, actinomyces or a combination of these. Different uni-axial deformations were induced on the biofilms and the load relaxations were measured over time. Linear-Regression-Analysis demonstrated that both the centrifugation coefficient for streptococci and induced deformation influenced the percentage relaxation. Centrifugal compaction significantly influenced relaxation only upon compression of the outermost 20% of the biofilm (p centrifugal compaction of initially adhering, centrifuged bacteria extend to the visco-elastic properties of biofilms, indicating that the initial bacterial layer influences the structure of the entire biofilm.

  18. Dynamic stress analysis of sewage centrifugal pump impeller based on two-way coupling method

    Science.gov (United States)

    Pei, Ji; Yuan, Shouqi; Yuan, Jianping

    2014-03-01

    Current research on the operational reliability of centrifugal pumps has mainly focused on hydrodynamic instability. However, the interaction between the fluid and structure has not been sufficiently considered; this interaction can cause vibration and dynamic stress, which can affect the reliability. In this study, the dynamic stresses in a single-blade centrifugal pump impeller are analysed under different operating conditions; the two-way coupling method is used to calculate the fluid-structure interaction. Three-dimensional unsteady Reynolds-averaged Navier-Stokes equations are solved with the SST k-ω turbulence model for the fluid in the whole flow passage, while transient structure dynamic analysis is used with the finite element method for the structure side. The dynamic stresses in the rotor system are computed according to the fourth strength theory. The stress results show that the highest stress is near the loose bearing and that the equivalent stress increases with the flow rate because the dynamic stresses are closely related to the pressure load. The stress distributions on the blade pressure side, suction side, leading edge, and trailing edge are each analysed for different flow rates; the highest stress distribution is found on the pressure side. On the blade pressure side, a relatively large stress is found near the trailing edge and hub side. Based on these results, a stress distribution prediction method is proposed for centrifugal pumps, which considers the interaction between the fluid and structure. The method can be used to check the dynamic stress at different flow rates when optimising the pump design to increase the pump reliability.

  19. The plasma centrifuge: A compact, low cost, stable isotope separator. Phase 2 final technical report, September 15, 1991 - September 14, 1995

    International Nuclear Information System (INIS)

    Enriched stable isotopes are required for production of radionuclides as well as for research and diagnostic uses. Science Research Laboratory (SRL) has developed a plasma centrifuge for moderate throughput of enriched stable isotopes, such as 13C, 17O, 18O, and 203Tl, for medical as well as other applications. Dwindling isotope stocks have restricted the use of enriched isotopes and their associated labeled organic molecules in medical imaging to very few research facilities because of high costs of isotope separation. With the introduction of the plasma centrifuge separator, the cost per separated gram of even rarely occurring isotopes (≤ 1% natural abundance) is potentially many times lower than with other separation technologies (cryogenic distillation and calutrons). The centrifuge is a simple, robust, pulsed electrical discharge device that has successfully demonstrated isotope separation of small (mg) quantities of 26Mg. Based on the results of the Phase 2 program, modest enhancements to the power supplies and cooling systems, a centrifuge separator will have high repetition rate (60 pps) and high duty cycle (60%) to produce in one month kilogram quantities of highly enriched stable isotopes. The centrifuge may be used in stand-alone operation or could be used as a high-throughput pre-separation stage with calutrons providing the final separation

  20. An in-line spectrophotometer on a centrifugal microfluidic platform for real-time protein determination and calibration.

    Science.gov (United States)

    Ding, Zhaoxiong; Zhang, Dongying; Wang, Guanghui; Tang, Minghui; Dong, Yumin; Zhang, Yixin; Ho, Ho-Pui; Zhang, Xuping

    2016-09-21

    In this paper, an in-line, low-cost, miniature and portable spectrophotometric detection system is presented and used for fast protein determination and calibration in centrifugal microfluidics. Our portable detection system is configured with paired emitter and detector diodes (PEDD), where the light beam between both LEDs is collimated with enhanced system tolerance. It is the first time that a physical model of PEDD is clearly presented, which could be modelled as a photosensitive RC oscillator. A portable centrifugal microfluidic system that contains a wireless port in real-time communication with a smartphone has been built to show that PEDD is an effective strategy for conducting rapid protein bioassays with detection performance comparable to that of a UV-vis spectrophotometer. The choice of centrifugal microfluidics offers the unique benefits of highly parallel fluidic actuation at high accuracy while there is no need for a pump, as inertial forces are present within the entire spinning disc and accurately controlled by varying the spinning speed. As a demonstration experiment, we have conducted the Bradford assay for bovine serum albumin (BSA) concentration calibration from 0 to 2 mg mL(-1). Moreover, a novel centrifugal disc with a spiral microchannel is proposed for automatic distribution and metering of the sample to all the parallel reactions at one time. The reported lab-on-a-disc scheme with PEDD detection may offer a solution for high-throughput assays, such as protein density calibration, drug screening and drug solubility measurement that require the handling of a large number of reactions in parallel.

  1. An in-line spectrophotometer on a centrifugal microfluidic platform for real-time protein determination and calibration.

    Science.gov (United States)

    Ding, Zhaoxiong; Zhang, Dongying; Wang, Guanghui; Tang, Minghui; Dong, Yumin; Zhang, Yixin; Ho, Ho-Pui; Zhang, Xuping

    2016-09-21

    In this paper, an in-line, low-cost, miniature and portable spectrophotometric detection system is presented and used for fast protein determination and calibration in centrifugal microfluidics. Our portable detection system is configured with paired emitter and detector diodes (PEDD), where the light beam between both LEDs is collimated with enhanced system tolerance. It is the first time that a physical model of PEDD is clearly presented, which could be modelled as a photosensitive RC oscillator. A portable centrifugal microfluidic system that contains a wireless port in real-time communication with a smartphone has been built to show that PEDD is an effective strategy for conducting rapid protein bioassays with detection performance comparable to that of a UV-vis spectrophotometer. The choice of centrifugal microfluidics offers the unique benefits of highly parallel fluidic actuation at high accuracy while there is no need for a pump, as inertial forces are present within the entire spinning disc and accurately controlled by varying the spinning speed. As a demonstration experiment, we have conducted the Bradford assay for bovine serum albumin (BSA) concentration calibration from 0 to 2 mg mL(-1). Moreover, a novel centrifugal disc with a spiral microchannel is proposed for automatic distribution and metering of the sample to all the parallel reactions at one time. The reported lab-on-a-disc scheme with PEDD detection may offer a solution for high-throughput assays, such as protein density calibration, drug screening and drug solubility measurement that require the handling of a large number of reactions in parallel. PMID:27531134

  2. Effects of a Nonuniform Tip Clearance Profile on the Performance and Flow Field in a Centrifugal Compressor

    OpenAIRE

    Yohan Jung; Minsuk Choi; Seonghwan Oh; Jehyun Baek

    2012-01-01

    This paper presents a numerical investigation of the effects of a nonuniform tip clearance profile on the performance and flow field in a centrifugal compressor with a vaneless diffuser. This study focuses in particular on the magnitude and location of the wake. Six impellers with different tip clearance profiles were tested in the flow simulations. The accuracy of the numerical simulations was assessed by comparing the experimental data with the computational results for a system characteriz...

  3. Fluidic Analysis in an Annular Centrifugal Contactor for Fuel Reprocessing

    International Nuclear Information System (INIS)

    An annular centrifugal contactor (ACC) is a promising device for fuel reprocessing process, because it offers several advantages—a smaller size, a smaller holdup volume, and a higher separation performance—over conventional contactors such as a mixer-settler and a pulse column. Fluid dynamics and dispersion in an ACC, which has a combined mixer/centrifuge structure, are closely related to its separation performance and capacity, and this information is useful in improving equipment design. In this paper, experimental and computational fluid dynamics (CFD) studies were conducted to analyze fluidic and dispersion behavior in ACCs. Multiphase mixing (water/TBP-dodecane/air) in the annular zone was observed by Particle Imaging Velocimetry, and the change in the fluidic and dispersion behavior was ascertained under several operational conditions. The results of the CFD studies, which considered multiphase turbulent flow in the annular and rotor interior zones, were in a good agreement with the experimental data. (author)

  4. Centrifuge modeling of PGD response of buried pipe

    Institute of Scientific and Technical Information of China (English)

    Michael O'Rourke; Vikram Gadicherla; Tarek Abdoun

    2005-01-01

    A new centrifuge based method for determining the response of continuous buried pipe to PGD is presented.The physical characteristics of the RPI's 100 g-ton geotechnical centrifuge and the current lifeline experiment split-box are described: The split-box contains the model pipeline and surrounding soil and is manufactured such that half can be offset, in flight, simulating PGD. In addition, governing similitude relations which allow one to determine the physical characteristics,(diameter, wall thickness and material modulus of elasticity) of the model pipeline are presented. Finally, recorded strains induced in two buried pipes with prototype diameters of 0.63 m and 0.95 m (24 and 36 inch) subject to 0.6 and 2.0 meters (2and 6 feet) of full scale fault offsets and presented and compared to corresponding FE results.

  5. Massively parallel single-molecule manipulation using centrifugal force

    CERN Document Server

    Halvorsen, Ken

    2009-01-01

    Precise manipulation of single molecules has already led to remarkable insights in physics, chemistry, biology and medicine. However, widespread adoption of single-molecule techniques has been impeded by equipment cost and the laborious nature of making measurements one molecule at a time. We have solved these issues with a new approach: massively parallel single-molecule force measurements using centrifugal force. This approach is realized in a novel instrument that we call the Centrifuge Force Microscope (CFM), in which objects in an orbiting sample are subjected to a calibration-free, macroscopically uniform force-field while their micro-to-nanoscopic motions are observed. We demonstrate high-throughput single-molecule force spectroscopy with this technique by performing thousands of rupture experiments in parallel, characterizing force-dependent unbinding kinetics of an antibody-antigen pair in minutes rather than days. Additionally, we verify the force accuracy of the instrument by measuring the well-est...

  6. Flow generation in a novel centrifugal diffuser test device

    Science.gov (United States)

    Vidos, P.

    1983-09-01

    Recognition of the need to develop optimum diffusers for advanced centrifugal compressors, resulted in the design and manufacture of a novel low-speed test facility for centrifugal diffuser testing. The CDTD was designed to allow the flow angle and wall boundary profiles into the test diffuser to be controlled by variable geometry in the flow generator. The present study reports on the design of the flow generator and the analysis of the internal flow using a NASA computer code (MERIDL). First test results are given and are compared with the results of a control volume analysis. The flow angle control technique was found to work effectively but to give somewhat smaller angles (by 4 deg) than were predicted. It was concluded that the information obtained would allow scaling of the device; however, an analysis code was needed which would accept the real physical boundary conditions.

  7. A centrifugal pump concept designed for multiple use in space

    Science.gov (United States)

    Wunderlich, E.; Wulz, H. G.

    A centrifugal pump concept was elaborated for a multiple application in future spacecrafts. Based on this concept a prototype of a small centrifugal pump was manufactured and comprehensively tested. The model pump has been approved in different test series with the fluids liquid ammonia and demineralized water. The design of the model pump was driven by strict requirements of COLUMBUS, namely long life, noiseless operation, minimum mass and low energy consumption. Because of its modular design and as a result of selected materials of multiple compatibility, this pump is suited for the delivery of various further fluids, such as freons, hydrocarbons, propellants (hydrazine) etc.. It is also capable of pumping corrosive or toxic fluids for laboratory processes in space. The wide speed range from about 1,00 to 20,000 rpm which corresponds to a flow from about 1 to 20 l/min, permits an energy saving adaption and flow control.

  8. Optimization of centrifugal pump cavitation performance based on CFD

    Science.gov (United States)

    Xie, S. F.; Wang, Y.; Liu, Z. C.; Zhu, Z. T.; Ning, C.; Zhao, L. F.

    2015-01-01

    In order to further improve the cavitation performance of a centrifugal pump, slots on impeller blade near inlet were studied and six groups of hydraulic model were designed. Base on cavitating flow feature inside a centrifugal pump, bubble growth and implosion are calculated from the Rayleigh-Plesset equation which describes the dynamic behavior of spherical bubble and RNG κ-epsilon model was employed to simulate and analyze the internal two-phase flow of the model pump under the same conditions. The simulation results show that slots on blade near inlet could improve the cavitation performance and cavitation performance improvement of the second group was more obvious. Under the same conditions, the pressure on the back of blade near inlet was higher than the pressure on the back of unmodified blade near inlet, and energy distribution in the flow channel between the two blades was more uniform with a small change of head.

  9. Isolation of Guttiferones from Renewable Parts of Symphonia globulifera by Centrifugal Partition Chromatography.

    Science.gov (United States)

    Cottet, Kevin; Fromentin, Yann; Kritsanida, Marina; Grougnet, Raphaël; Odonne, Guillaume; Duplais, Christophe; Michel, Sylvie; Lallemand, Marie-Christine

    2015-11-01

    The aim of this study was to investigate the species Symphonia globulifera, a source of polycyclic polyprenylated acyl phloroglucinols such as guttiferone A, which is known to exhibit a variety of biological activities including noticeable antileishmanial properties. Our goal was the identification and the quantification of guttiferone A in different renewable parts of S. globulifera and its preparative isolation. To the best of our knowledge, there is no data concerning its mechanism of action. Consequently, it is particularly interesting to isolate it in gram quantities in order to establish structure activity relationship studies. After performing high-performance liquid chromatography profiles detecting the presence of guttiferone A and proceeding to its quantification, a centrifugal partition chromatography methodology using a two-phase solvent system of cyclohexane/ethyl acetate/methanol/water (20 :  1 :  20 : 1, v/v/v/v) was applied to each extract. In conclusion, a centrifugal partition chromatography system has been developed to ensure a fast, reliable, and scalable way to isolate, with a high level of purity, guttiferone A from five renewable parts of S. globulifera. Moreover, this methodology can be extended to the isolation of other polycyclic polyprenylated acyl phloroglucinols such as guttiferones B, C, and D. PMID:26393938

  10. Designing and modeling a centrifugal microfluidic device to separate target blood cells

    Science.gov (United States)

    Shamloo, Amir; Selahi, AmirAli; Madadelahi, Masoud

    2016-03-01

    The objective of this study is to design a novel and efficient portable lab-on-a-CD (LOCD) microfluidic device for separation of specific cells (target cells) using magnetic beads. In this study the results are shown for neutrophils as target cells. However, other kinds of target cells can be separated in a similar approach. The designed microfluidics can be utilized as a point of care system for neutrophil detection. This microfluidic system employs centrifugal and magnetic forces for separation. After model validation by the experimental data in the literature (that may be used as a design tool for developing centrifugo-magnetophoretic devices), two models are presented for separation of target cells using magnetic beads. The first model consists of one container in the inlet section and two containers in the outlets. Initially, the inlet container is filled with diluted blood sample which is a mixture of red blood cells (RBCs) plus neutrophils which are attached to Magnetic beads. It is shown that by using centrifugal and magnetic forces, this model can separate all neutrophils with recovery factor of ~100%. In the second model, due to excess of magnetic beads in usual experimental analysis (to ensure that all target cells are attached to them) the geometry is improved by adding a third outlet for these free magnetic beads. It is shown that at angular velocity of 45 rad s-1, recovery factor of 100% is achievable for RBCs, free magnetic beads and neutrophils as target cells.

  11. Designing and modeling a centrifugal microfluidic device to separate target blood cells

    International Nuclear Information System (INIS)

    The objective of this study is to design a novel and efficient portable lab-on-a-CD (LOCD) microfluidic device for separation of specific cells (target cells) using magnetic beads. In this study the results are shown for neutrophils as target cells. However, other kinds of target cells can be separated in a similar approach. The designed microfluidics can be utilized as a point of care system for neutrophil detection. This microfluidic system employs centrifugal and magnetic forces for separation. After model validation by the experimental data in the literature (that may be used as a design tool for developing centrifugo-magnetophoretic devices), two models are presented for separation of target cells using magnetic beads. The first model consists of one container in the inlet section and two containers in the outlets. Initially, the inlet container is filled with diluted blood sample which is a mixture of red blood cells (RBCs) plus neutrophils which are attached to Magnetic beads. It is shown that by using centrifugal and magnetic forces, this model can separate all neutrophils with recovery factor of ∼100%. In the second model, due to excess of magnetic beads in usual experimental analysis (to ensure that all target cells are attached to them) the geometry is improved by adding a third outlet for these free magnetic beads. It is shown that at angular velocity of 45 rad s−1, recovery factor of 100% is achievable for RBCs, free magnetic beads and neutrophils as target cells. (paper)

  12. Centrifuge modeling of soil atmosphere interaction using climatic chamber

    OpenAIRE

    CAICEDO, B; TRISTANCHO, J; THOREL, Luc

    2010-01-01

    Soil-atmospheric interaction processes such as infiltration or evaporation can have a significant effect on the behavior of geotechnical structures located near the soil surface. This paper focuses on the drying process of soils due to evaporation. The scaling laws are analyzed and the results of the application of two cycles of heating and cooling on a soil mass are presented. Based on these results, conclusions about the feasibility of reproducing evaporation on centrifuge models are recomm...

  13. Centrifugal effects in a weakly ionized rotating gas

    International Nuclear Information System (INIS)

    The author deals with a weakly ionized gas rotating under the influence of the Lorentz force in a cylindrical vessel. This force occurs if an electrical current flows across a magnetic field. The investigation concerns the possibility to bring a neutral gas into rotation by a relatively small number of charged particles (ions and electrons) on which the Lorentz force is acting. Also the possibility to use the centrifugal force, due to the rotation of the gas, for mass separation, is discussed. (Auth.)

  14. Origins of hydrodynamic forces on centrifugal pump impellers

    OpenAIRE

    Adkins, Douglas R.; Brennen, Christopher E.

    1986-01-01

    Hydrodynamic interactions that occur between a centrifugal pump impeller and volute are experimentally and theoretically investigated. The theoretical analysis considers the inability of the blades to perfectly guide the flow through the impeller, and also includes a quasi-one dimensional treatment of the flow in the volute. The disturbance at the impeller discharge and the resulting forces are determined by the theoretical model. The model is then extended to obtain the hydrodynamic force pe...

  15. Analyses of Hydrodynamic Radial Forces on Centrifugal Pump Impellers

    OpenAIRE

    Adkins, D. R.; Brennen, C. E.

    1988-01-01

    Hydrodynamic interactions that occur between a centrifugal pump impeller and a volute are experimentally and theoretically investigates. The theoretical analysis considers the inability of the blades to perfectly guide the flow through the impeller, and also includes a quasi-one dimensional treatment of flow in the volute. Flow disturbances at the impeller discharge and the resulting forces are determined by the theoretical model. The model is then extended to obtain the hydrodynamic force...

  16. Computational and Experimental Study of an Industrial Centrifugal Compressor Volute

    Institute of Scientific and Technical Information of China (English)

    HarriPitkanen; HannuEsa; 等

    2000-01-01

    A centrifugal compressor with a vaneless diffuser was studied experimentally and numericallly.The main target of the study was to analyze the volute flow.Two different volute geometries was studied.The numerical solution was done by using a steady-state RANS code at both design and off-design conditions.Both calculated and measured pressure and velocity distributions are presented.

  17. Centrifugal stretching of 170Hf in the interacting boson model

    Directory of Open Access Journals (Sweden)

    Werner V.

    2014-03-01

    Full Text Available We present the results of a recent experiment to deduce lifetimes of members of the ground state rotational band of 170Hf, which show the effect of centrifugal stretching in this deformed isotope. Results are compared to the geometrical confined beta-soft(CBS rotor model, as well as to the interacting boson model (IBM. Two methods to correct for effects due to the finite valence space within the IBM are proposed.

  18. Purification of crime scene DNA extracts using centrifugal filter devices

    OpenAIRE

    Norén, Lina; Hedell, Ronny; Ansell, Ricky; Hedman, Johannes

    2013-01-01

    BACKGROUND: The success of forensic DNA analysis is limited by the size, quality and purity of biological evidence found at crime scenes. Sample impurities can inhibit PCR, resulting in partial or negative DNA profiles. Various DNA purification methods are applied to remove impurities, for example, employing centrifugal filter devices. However, irrespective of method, DNA purification leads to DNA loss. Here we evaluate the filter devices Amicon Ultra 30 K and Microsep 30 K with respect to re...

  19. A Review of Centrifugal Testing of Gasoline Contamination and Remediation

    OpenAIRE

    Jay N. Meegoda; Liming Hu

    2011-01-01

    Leaking underground storage tanks (USTs) containing gasoline represent a significant public health hazard. Virtually undetectable to the UST owner, gasoline leaks can contaminate groundwater supplies. In order to develop remediation plans one must know the extent of gasoline contamination. Centrifugal simulations showed that in silty and sandy soils gasoline moved due to the physical process of advection and was retained as a pool of free products above the water table. However, in clayey soi...

  20. Development and Design of a Centrifugal Compressor Volute

    OpenAIRE

    Cheng Xu; Michael Müller

    2005-01-01

    The volute is one of the key components of a centrifugal compressor. The design of the volute not only impacts the compressor efficiency but also influences the operating range. The detailed flow simulation presented here helps to better understand the volute flow mechanisms and provide design guidance in volute design to meet performance goals. In this study, the viscous Navier-Stokes equations are used to simulate the flow inside the vaneless diffuser and volute. The de...

  1. Inverse Design of Centrifugal Compressor Stages Using a Meanline Approach

    OpenAIRE

    Yuri Biba; Peter Menegay

    2004-01-01

    This article discusses an approach for determining meanline geometric parameters of centrifugal compressor stages given specified performance requirements. This is commonly known as the inverse design approach. The opposite process, that of calculating performance parameters based on geometry input is usually called analysis, or direct calculation. An algorithm and computer code implementing the inverse approach is described. As an alternative to commercially available inverse design codes...

  2. A Novel Aerodynamic Design Method for Centrifugal Compressor Impeller

    OpenAIRE

    Mahdi Nili-Ahmadabadi; mohammad durali; Ali Hajilouy Benisi

    2014-01-01

    This paper describes a new quasi-3D design method for centrifugal compressor impeller. The method links up a novel inverse design algorithm, called Ball-Spine Algorithm (BSA), and a quasi-3D analysis. Euler equation is solved on the impeller meridional plane. The unknown boundaries (hub and shroud) of numerical domain are iteratively modified by BSA until a target pressure distribution in flow passage is reached. To validate the quasi-3D analysis code, existing compressor impeller is investig...

  3. Comparison of Two Diffusers in a Transonic Centrifugal Compressor

    OpenAIRE

    Koji Nakagawa; Hiroshi Hayami; Yuichi Keimi

    2003-01-01

    Flow mechanisms suppressing the flow separation in two diffusers, a low-solidity cascade diffuser and a vaned diffuser with additional small vanes near the inlet, were compared mainly by numerical simulation. As the superiority of the low-solidity cascade diffuser was expected, a series of experiments was conducted using a transonic centrifugal compressor with a maximum pressure ratio of 7. The performance of the compressor with the vaned diffuser was comparable to that of the low-solidity ca...

  4. Optimal Design of a Centrifugal Compressor Impeller Using Evolutionary Algorithms

    OpenAIRE

    Soo-Yong Cho; Kook-Young Ahn; Young-Duk Lee; Young-Cheol Kim

    2012-01-01

    An optimization study was conducted on a centrifugal compressor. Eight design variables were chosen from the control points for the Bezier curves which widely influenced the geometric variation; four design variables were selected to optimize the flow passage between the hub and the shroud, and other four design variables were used to improve the performance of the impeller blade. As an optimization algorithm, an artificial neural network (ANN) was adopted. Initially, the design of experiment...

  5. Measurement and Calibration of Centrifugal Compressor Pressure Scanning Instrumentation

    OpenAIRE

    Rivas, Jose R; Lou, Fangyuan; Harrison, Herbert "Trey"; Key, Nicole

    2015-01-01

    The compressor is a key component of a jet engine necessary to compress air for the combustion process. Research to optimize compressor efficiency through the understanding of air flow behavior has led to increased efforts in creating modern compressor test facilities. In collaboration with Honeywell, the High Speed Compressor facility at Zucrow Laboratories has built a centrifugal compressor test cell with instrumentation to measure the temperatures and pressures of the air flow. This facili...

  6. Impeller Design of a Centrifugal Fan with Blade Optimization

    OpenAIRE

    Yu-Tai Lee; Vineet Ahuja; Ashvin Hosangadi; Michael E. Slipper; Lawrence P. Mulvihill; Roger Birkbeck; Coleman, Roderick M.

    2011-01-01

    A method is presented for redesigning a centrifugal impeller and its inlet duct. The double-discharge volute casing is a structural constraint and is maintained for its shape. The redesign effort was geared towards meeting the design volute exit pressure while reducing the power required to operate the fan. Given the high performance of the baseline impeller, the redesign adopted a high-fidelity CFD-based computational approach capable of accounting for all aerodynamic losses. The present eff...

  7. Centrifuge modeling of rocking-isolated inelastic RC bridge piers

    OpenAIRE

    Loli, Marianna; Knappett, Jonathan A; Brown, Michael J.; Anastasopoulos, Ioannis; GAZETAS, George

    2014-01-01

    Experimental proof is provided of an unconventional seismic design concept, which is based on deliberately underdesigning shallow foundations to promote intense rocking oscillations and thereby to dramatically improve the seismic resilience of structures. Termed rocking isolation, this new seismic design philosophy is investigated through a series of dynamic centrifuge experiments on properly scaled models of a modern reinforced concrete (RC) bridge pier. The experimental method reproduces th...

  8. Comparative hemolysis study of clinically available centrifugal pumps.

    Science.gov (United States)

    Naito, K; Suenaga, E; Cao, Z L; Suda, H; Ueno, T; Natsuaki, M; Itoh, T

    1996-06-01

    Centrifugal pumps have become important devices for cardiopulmonary bypass and circulatory assistance. Five types of centrifugal pumps are clinically available in Japan. To evaluate the blood trauma caused by centrifugal pumps, a comparative hemolysis study was performed under identical conditions. In vitro hemolysis test circuits were constructed to operate the BioMedicus BP-80 (Medtronic, BioMedicus), Sarns Delphin (Sarns/3M Healthcare), Isoflow (St. Jude Medical [SJM]), HPM-15 (Nikkiso), and Capiox CX-SP45 (Terumo). The hemolysis test loop consisted of two 1.5 m lengths of polyvinyl chloride tubing with a 3/8-inch internal diameter, a reservoir with a sampling port, and a pump head. All pumps were set to flow at 6 L/min against the total pressure head of 120 mm Hg. Experiments were conducted simultaneously for 6 h at room temperature (21 degrees C) with fresh bovine blood. Blood samples for plasma-free hemoglobin testing were taken, and the change in temperature at the pump outlet port was measured during the experiment. The mean pump rotational speeds were 1,570, 1,374, 1,438, 1,944, and 1,296 rpm, and the normalized indexes of hemolysis were 0.00070, 0.00745, 0.00096, 0.00066, 0.00090 g/100 L for the BP-80, Sarns, SJM, Nikkiso, and Terumo pumps, respectively. The change in temperature at the pump outlet port was the least for the Nikkiso pump (1.8 degrees C) and the most with the SJM pump (3.8 degrees C). This study showed that there is no relationship between the pump rotational speed (rpm) and the normalized index of hemolysis in 5 types of centrifugal pumps. The pump design and number of impellers could be more notable factors in blood damage.

  9. Effects of Different Blade Angle Distributions on Centrifugal Compressor Performance

    OpenAIRE

    Pekka Röyttä; Aki Grönman; Ahti Jaatinen; Teemu Turunen-Saaresti; Jari Backman

    2009-01-01

    A centrifugal compressor with three different shrouded 2D impellers is studied numerically. All impellers have the same dimensions, and they only differ in channel length and geometry. Noticeable differences in efficiency are observed. Two different turbulence models, Chien's k-ε and k-ω SST, are compared. For this case, k-ω SST was found more realistic. The hypothesis that pressure losses in a curved duct and in an impeller passage behave similarly is suggested and found inadequate.

  10. Numerical simulation of the countercurrent flow in a gas centrifuge

    Energy Technology Data Exchange (ETDEWEB)

    Cloutman, L.D.; Gentry, R.A.

    1983-03-01

    We present a finite difference method for the numerical simulation of the axisymmetric countercurrent flow in a gas centrifuge. A time-marching technique is used to relax an arbitrary initial condition to the desired steady-state solution. All boundary layers can be resolved, and nonlinear effects may be included. Numerical examples are presented. We conclude that this technique is capable of predicting accurately the performance of a wide variety of machines under all operating conditions of interest.

  11. Axial and centrifugal pump meanline performance analysis

    Science.gov (United States)

    Veres, Joseph P.

    1994-01-01

    A meanline pump flow modeling method has been developed to provide a fast capability for modeling pumps of cryogenic rocket engines. Based on this method, a meanline pump flow code (PUMPA) has been written that can predict the performance of pumps at off-design operating conditions, given the loss of the diffusion system at the design point. The design point rotor efficiency is obtained from empirically derived correlations of loss to rotor specific speed. The rapid input setup and computer run time for the meanline pump flow code makes it an effective analysis and conceptual design tool. The map generation capabilities of the PUMPA code provide the information needed for interfacing with a rocket engine system modeling code.

  12. The effect of contact angles and capillary dimensions on the burst frequency of super hydrophilic and hydrophilic centrifugal microfluidic platforms, a CFD study.

    Science.gov (United States)

    Kazemzadeh, Amin; Ganesan, Poo; Ibrahim, Fatimah; He, Shuisheng; Madou, Marc J

    2013-01-01

    This paper employs the volume of fluid (VOF) method to numerically investigate the effect of the width, height, and contact angles on burst frequencies of super hydrophilic and hydrophilic capillary valves in centrifugal microfluidic systems. Existing experimental results in the literature have been used to validate the implementation of the numerical method. The performance of capillary valves in the rectangular and the circular microfluidic structures on super hydrophilic centrifugal microfluidic platforms is studied. The numerical results are also compared with the existing theoretical models and the differences are discussed. Our experimental and computed results show a minimum burst frequency occurring at square capillaries and this result is useful for designing and developing more sophisticated networks of capillary valves. It also predicts that in super hydrophilic microfluidics, the fluid leaks consistently from the capillary valve at low pressures which can disrupt the biomedical procedures in centrifugal microfluidic platforms. PMID:24069169

  13. The effect of contact angles and capillary dimensions on the burst frequency of super hydrophilic and hydrophilic centrifugal microfluidic platforms, a CFD study.

    Directory of Open Access Journals (Sweden)

    Amin Kazemzadeh

    Full Text Available This paper employs the volume of fluid (VOF method to numerically investigate the effect of the width, height, and contact angles on burst frequencies of super hydrophilic and hydrophilic capillary valves in centrifugal microfluidic systems. Existing experimental results in the literature have been used to validate the implementation of the numerical method. The performance of capillary valves in the rectangular and the circular microfluidic structures on super hydrophilic centrifugal microfluidic platforms is studied. The numerical results are also compared with the existing theoretical models and the differences are discussed. Our experimental and computed results show a minimum burst frequency occurring at square capillaries and this result is useful for designing and developing more sophisticated networks of capillary valves. It also predicts that in super hydrophilic microfluidics, the fluid leaks consistently from the capillary valve at low pressures which can disrupt the biomedical procedures in centrifugal microfluidic platforms.

  14. The Review on Energy Saving Technology Development and Prospect of Centrifugal Pump%离心泵的节能技术发展及前景分析

    Institute of Scientific and Technical Information of China (English)

    凌素琴; 陈勇; 刘莉

    2014-01-01

    It analyzes the current main problems of domestic energy saving technology in centrifugal pump manu -facture , presents the detail technical way for centrifugal pump energy saving from the pump design , manufactur-ing, the system cooperation with connection accessories , the integration of mechanical and electrical instrument development and application .Finally it describes the prospect of energy saving technology for centrifugal pump .%分析了目前国内离心泵在节能方面存在的主要问题,分别从单泵的设计和制造、系统的连接附件配合、机电仪一体化发展以及使用方面有针对性地提出了离心泵节能的技术途径,并对离心泵节能技术客观地进行了前景分析。

  15. Phase characterization in two centrifugally cast HK stainless steel tubes

    International Nuclear Information System (INIS)

    The petrochemical industry has been using 25% Cr - 20% Ni centrifugally cast stainless steel since the early 1960s in reformer and pyrolysis furnaces. This class of material has replaced the traditional superalloys showing similar creep behavior, with substantial reduction in costs. The use of the centrifugal casting technique for tube production has also contributed to better quality in these components. During the past two decades, several studies have been conducted concerning the improvement in the performance of this material at high temperatures. Some of them were related to failure analysis and life prediction, while others were related to the chemical composition balance and to new alloying procedures. As a consequence, a new generation of centrifugally cast steels has been developed in the form of niobium-modified HK and HP steels. The creep resistance of these alloys appears to be dependent on the composition, morphology, and distribution of carbides that form within them. The purpose of the study reported herein is to characterize the precipitation effects occurring during long- term service in two HK-type steels, one being of basic HK composition and the other a niobium-modified alloy

  16. Governing Principles of Alginate Microparticle Synthesis with Centrifugal Forces.

    Science.gov (United States)

    Eral, Huseyin Burak; Safai, Eric R; Keshavarz, Bavand; Kim, Jae Jung; Lee, Jisoek; Doyle, P S

    2016-07-19

    A controlled synthesis of polymeric particles is becoming increasingly important because of emerging applications ranging from medical diagnostics to self-assembly. Centrifugal synthesis of hydrogel microparticles is a promising method, combining rapid particle synthesis and the ease of manufacturing with readily available laboratory equipment. This method utilizes centrifugal forces to extrude an aqueous polymer solution, sodium alginate (NaALG) through a nozzle. The extruded solution forms droplets that quickly cross-link upon contact with aqueous calcium chloride (CaCl2) solution to form hydrogel particles. The size distribution of hydrogel particles is dictated by the pinch-off behavior of the extruded solution through a balance of inertial, viscous, and surface tension stresses. We identify the parameters dictating the particle size and provide a numerical correlation predicting the average particle size. Furthermore, we create a phase map identifying different pinch-off regimes (dripping without satellites, dripping with satellites, and jetting), explaining the corresponding particle size distributions, and present scaling arguments predicting the transition between regimes. By shedding light on the underlying physics, this study enables the rational design and operation of particle synthesis by centrifugal forces.

  17. Numerical Analysis and Centrifuge Modeling of Shallow Foundations

    Institute of Scientific and Technical Information of China (English)

    罗强; 栾茂田; 杨蕴明; 王忠涛; 赵守正

    2014-01-01

    The influence of non-coaxial constitutive model on predictions of dense sand behavior is investigated in this paper. The non-coaxial model with strain softening plasticity is applied into finite-element program ABAQUS, which is first used to predict the stress-strain behavior and the non-coaxial characteristic between the orientations of the principal stress and principal plastic strain rate in simple shear tests. The model is also used to predict load settlement responses and bearing capacity factors of shallow foundations. A series of centrifuge tests for shallow foundations on saturated dense sand are performed under drained conditions and the test results are compared with the corresponding numerical results. Various footing dimensions, depths of embedment, and footing shapes are considered in these tests. In view of the load settlement relationships, the stiffness of the load-displacement curves is significantly affected by the non-coaxial model compared with those predicted by the coaxial model, and a lower value of non-coaxial modulus gives a softer response. Considering the soil behavior at failure, the coaxial model predictions of bearing capacity factors are more advanced than those of centrifuge test results and the non-coaxial model results;besides, the non-coaxial model gives better predictions. The non-coaxial model predictions are closer to those of the centrifuge results when a proper non-coaxial plastic modulus is chosen.

  18. Flow measurements in a centrifugal diffusor test device

    Science.gov (United States)

    Vitting, T.

    1985-06-01

    This work sought to verify concepts used in the design of a large scale, low speed, radial cascade wind tunnel which was to be used to investigate flow phenomena in and the performance of vaned radial diffusors. A major contributor to centrifugal compressor efficiency is the performance of the vaned diffusor which closely follows the impeller of the compressor. The purpose of this diffusor is to efficiently convert most of the kinetic energy of the transonic flow entering the vane into pressure. The need for an experimental facility which could simulate adequately, at low cost and in a controlled way, the environment of the centrifugal compressor motivated the development of the Centrifugal Diffusor Test Device (CDTD). It was expected that the generation of a three dimensional flow would provide improved empirical data on annular cascade performance. This measurement program surveyed the axial and circumferential uniformity of the flow at the inlet of a transonic wedge-type blading mounted in the device. Evaluation of the results showed the flow uniformity to be unsatisfactory. Leakage and other small perturbations in the flow field in the swirl generator are believed to be amplified by the basic flow configuration of the device.

  19. Governing Principles of Alginate Microparticle Synthesis with Centrifugal Forces.

    Science.gov (United States)

    Eral, Huseyin Burak; Safai, Eric R; Keshavarz, Bavand; Kim, Jae Jung; Lee, Jisoek; Doyle, P S

    2016-07-19

    A controlled synthesis of polymeric particles is becoming increasingly important because of emerging applications ranging from medical diagnostics to self-assembly. Centrifugal synthesis of hydrogel microparticles is a promising method, combining rapid particle synthesis and the ease of manufacturing with readily available laboratory equipment. This method utilizes centrifugal forces to extrude an aqueous polymer solution, sodium alginate (NaALG) through a nozzle. The extruded solution forms droplets that quickly cross-link upon contact with aqueous calcium chloride (CaCl2) solution to form hydrogel particles. The size distribution of hydrogel particles is dictated by the pinch-off behavior of the extruded solution through a balance of inertial, viscous, and surface tension stresses. We identify the parameters dictating the particle size and provide a numerical correlation predicting the average particle size. Furthermore, we create a phase map identifying different pinch-off regimes (dripping without satellites, dripping with satellites, and jetting), explaining the corresponding particle size distributions, and present scaling arguments predicting the transition between regimes. By shedding light on the underlying physics, this study enables the rational design and operation of particle synthesis by centrifugal forces. PMID:27311392

  20. Subchronic centrifugal mechanical assist in an unheparinized calf model.

    Science.gov (United States)

    Wagner-Mann, C; Curtis, J; Mann, F A; Turk, J; Demmy, T; Turpin, T

    1996-06-01

    The purpose of this study was to determine whether the major centrifugal pumps currently in use in the United States (Medtronic, BioMedicus BioPump and Carmeda-coated BioPump, Sarns 3M centrifugal pump, and St. Jude Medical Lifestream) could function as left mechanical assist devices in the subchronic (72 h) unheparinized calf model. Calves were instrumented for left atrial to aorta ex vivo assist, and the pump flow was set at 3.5 +/- 0.4 L/min. Two calves (Sarns 3M and St. Jude) survived 72 h of pumping without clinical complications. The other 2 calves died at 62 and 66 h (Medtronic BioPump and Carmeda-coated BioPump, respectively); both had pelvic limb paralysis. The seal of the Sarns 3M pump head ruptured after approximately 36 h of pumping and required replacement. On postmortem examination, pump-associated thromboembolic lesions were detected in 3 of the 4 calves in one or more of the following organs: kidneys, pancreas, abomasum, duodenum, ileum, spleen, and lumbar spinal cord. The calf with the Sarns 3M pump had no discernable lesions. Because of the clinical abnormalities and postmortem lesions in the unheparinized calf model, it was suggested that anticoagulation is necessary for conducting centrifugal mechanical assist studies in calves using presently available technology.

  1. Determination of Wear That Can be Formed at the Stainless Steel Wheels of the Centrifuge Pumps Used at Agricultural Irrigation

    Directory of Open Access Journals (Sweden)

    E. Yuksel

    2009-09-01

    Full Text Available The extent of this work is operating characteristics of a horizontal shafted centrifugal pump (which has stainless steel wheel which has been operated for 7 hours on the average. A closed circuit pump system (circulating within itself which was formed by attaching a horizontal shafted centrifugal pump which can be used in irrigation applications with a drum has been operated for 150 hours at laboratory conditions. To define the operating properties of the pump, its operating characteristics were measured in respect to ISO 2548. Furthermore, observations have been done to determine whether there is a connection between operating characteristics of the pump and the wear and corrosion occured on the wheel or not.

  2. Challenges in the Use of Compact Disc-Based Centrifugal Microfluidics for Healthcare Diagnostics at the Extreme Point of Care

    Directory of Open Access Journals (Sweden)

    Jordon Gilmore

    2016-03-01

    Full Text Available Since its inception, Compact Disc (CD-based centrifugal microfluidic technology has drawn a great deal of interest within research communities due to its potential use in biomedical applications. The technology has been referred to by different names, including compact-disc microfluidics, lab-on-a-disk, lab-on-a-CD and bio-disk. This paper critically reviews the state-of-the-art in CD-based centrifugal microfluidics devices and attempts to identify the challenges that, if solved, would enable their use in the extreme point of care. Sample actuation, manufacturing, reagent storage and implementation, target multiplexing, bio-particle detection, required hardware and system disposal, and sustainability are the topics of focus.

  3. Evaluation of HL-20 roller pump and Rotaflow centrifugal pump on perfusion quality and gaseous microemboli delivery.

    Science.gov (United States)

    Yee, Stella; Qiu, Feng; Su, Xiaowei; Rider, Alan; Kunselman, Allen R; Guan, Yulong; Undar, Akif

    2010-11-01

    The purpose of this study was to compare the HL-20 roller pump (Jostra USA, Austin, TX, USA) and Rotaflow centrifugal pump (Jostra USA) on hemodynamic energy production and gaseous microemboli (GME) delivery in a simulated neonatal cardiopulmonary bypass (CPB) circuit under nonpulsatile perfusion. This study employed a simulated model of the pediatric CPB including a Jostra HL-20 heart-lung machine (or a Rotaflow centrifugal pump), a Capiox BabyRX05 oxygenator (Terumo Corporation, Tokyo, Japan), a Capiox pediatric arterial filter (Terumo Corporation), and ¼-inch tubing. The total volume of the experimental system was 700mL (500mL for the circuit and 200mL for the pseudo neonatal patient). The hematocrit was maintained at 30% using human blood. At the beginning of each trial, a 5mL bolus of air was injected into the venous line. Both GME data and pressure values were recorded at postpump and postoxygenator sites. All the experiments were conducted under nonpulsatile perfusion at three flow rates (500, 750, and 1000mL/min) and three blood temperatures (35, 30, and 25°C). As n=6 for each setup, a total of 108 trials were done. The total number of GME increased as temperature decreased from 35°C to 25°C in the trials using the HL-20 roller pump while the opposite effect occurred when using the Rotaflow centrifugal pump. At a given temperature, total GME counts increased with increasing flow rates for both pumps. Results indicated the Rotaflow centrifugal pump delivered significantly fewer microemboli compared to the HL-20 roller pump, especially under high flow rates. Less than 10% of total microemboli were larger than 40µm in size and the majority of GME were in the 0-20µm class in all trials. Postpump total hemodynamic energy (THE) increased with increasing flow rates and decreasing temperatures in both circuits using these two pumps. The HL-20 roller pump delivered more THE than the Rotaflow centrifugal pump at all tested flow rates and temperature conditions

  4. Dynamo generated by the centrifugal instability

    CERN Document Server

    Marcotte, Florence

    2016-01-01

    We present a new scenario for magnetic field amplification where an electrically conducting fluid is confined in a differentially rotating, spherical shell with thin aspect-ratio. When the angular momentum sufficiently decreases outwards, an hydrodynamic instability develops in the equatorial region, characterised by pairs of counter-rotating toroidal vortices similar to those observed in cylindrical Couette flow. These spherical Taylor-Couette vortices generate a subcritical dynamo magnetic field dominated by non-axisymmetric components. We show that the critical magnetic Reynolds number seems to reach a constant value at large Reynolds number and that the global rotation can strongly decrease the dynamo onset. Our numerical results are understood within the framework of a simple dynamical system, and we propose a low-dimensional model for subcritical dynamo bifurcations. Implications for both laboratory dynamos and astrophysical magnetic fields are finally discussed.

  5. Small centrifugal pumps for low thrust rockets

    Science.gov (United States)

    Gulbrandsen, N. C.; Furst, R. B.; Burgess, R. M.; Scheer, D. D.

    1985-01-01

    This paper presents the results of a combined analytical and experimental investigation of low specific speed pumps for potential use as components of propellant feed systems for low thrust rocket engines. Shrouded impellers and open face impellers were tested in volute type and vaned diffuser type pumps. Full- and partial-emission diffusers and full- and partial-admission impellers were tested. Axial and radial loads, head and efficiency versus flow, and cavitation tests were conducted. Predicted performance of two pumps are compared when pumping water and liquid hydrogen. Detailed pressure loss and parasitic power values are presented for two pump configurations. Partial-emission diffusers were found to permit use of larger impeller and diffuser passages with a minimal performance penalty. Normal manufacturing tolerances were found to result in substantial power requirement variation with only a small pressure rise change. Impeller wear ring leakage was found to reduce pump pressure rise to an increasing degree as the pump flowrate was decreased.

  6. Evaluation of hydraulic radial forces on the impeller by the volute in a centrifugal rotary blood pump.

    Science.gov (United States)

    Boehning, Fiete; Timms, Daniel L; Amaral, Felipe; Oliveira, Leonardo; Graefe, Roland; Hsu, Po-Lin; Schmitz-Rode, Thomas; Steinseifer, Ulrich

    2011-08-01

    In many state-of-the-art rotary blood pumps for long-term ventricular assistance, the impeller is suspended within the casing by magnetic or hydrodynamic means. For the design of such suspension systems, profound knowledge of the acting forces on the impeller is crucial. Hydrodynamic bearings running at low clearance gaps can yield increased blood damage and magnetic bearings counteracting high forces consume excessive power. Most current rotary blood pump devices with contactless bearings are centrifugal pumps that incorporate a radial diffuser volute where hydraulic forces on the impeller develop. The yielding radial forces are highly dependent on impeller design, operating point and volute design. There are three basic types of volute design--singular, circular, and double volute. In this study, the hydraulic radial forces on the impeller created by the volute in an investigational centrifugal blood pump are evaluated and discussed with regard to the choice of contactless suspension systems. Each volute type was tested experimentally in a centrifugal pump test setup at various rotational speeds and flow rates. For the pump's design point at 5 L/min and 2500 rpm, the single volute had the lowest radial force (∼0 N), the circular volute yielded the highest force (∼2 N), and the double volute possessed a force of approx. 0.5 N. Results of radial force magnitude and direction were obtained and compared with a previously performed computational fluid dynamics (CFD) study.

  7. Response of centrifugal blowers to simulated tornado transients, July-September 1981

    International Nuclear Information System (INIS)

    During this quarter, quasi-steady and dynamic testing of the 24-in. centrifugal blower was completed using the blowdown facility located at New Mexico State University. The data were obtained using a new digital data-acquisition system. Software was developed at the Los Alamos National Laboratory to reduce the dynamic test data and create computer-generated movies showing the dynamic performance of the blower under simulated tornado transient pressure conditions relative to its quasi-steady-state performance. Currently, quadrant-four (outrunning flow) data have been reduced for the most severe and a less severe tornado pressure transient. The results indicate that both the quasi-steady and dynamic blower performance are very similar. Some hysteresis in the dynamic performance occurs because of rotational inertia effects in the blower rotor and drive system. Currently quadrant-two (backflow) data are being transferred to the LTSS computer system at Los Alamos and will be reduced shortly

  8. Droplet centrifugation, droplet DNA extraction, and rapid droplet thermocycling for simpler and faster PCR assay using wire-guided manipulations

    Directory of Open Access Journals (Sweden)

    You David J

    2012-09-01

    Full Text Available Abstract A computer numerical control (CNC apparatus was used to perform droplet centrifugation, droplet DNA extraction, and rapid droplet thermocycling on a single superhydrophobic surface and a multi-chambered PCB heater. Droplets were manipulated using “wire-guided” method (a pipette tip was used in this study. This methodology can be easily adapted to existing commercial robotic pipetting system, while demonstrated added capabilities such as vibrational mixing, high-speed centrifuging of droplets, simple DNA extraction utilizing the hydrophobicity difference between the tip and the superhydrophobic surface, and rapid thermocycling with a moving droplet, all with wire-guided droplet manipulations on a superhydrophobic surface and a multi-chambered PCB heater (i.e., not on a 96-well plate. Serial dilutions were demonstrated for diluting sample matrix. Centrifuging was demonstrated by rotating a 10 μL droplet at 2300 round per minute, concentrating E. coli by more than 3-fold within 3 min. DNA extraction was demonstrated from E. coli sample utilizing the disposable pipette tip to cleverly attract the extracted DNA from the droplet residing on a superhydrophobic surface, which took less than 10 min. Following extraction, the 1500 bp sequence of Peptidase D from E. coli was amplified using rapid droplet thermocycling, which took 10 min for 30 cycles. The total assay time was 23 min, including droplet centrifugation, droplet DNA extraction and rapid droplet thermocycling. Evaporation from of 10 μL droplets was not significant during these procedures, since the longest time exposure to air and the vibrations was less than 5 min (during DNA extraction. The results of these sequentially executed processes were analyzed using gel electrophoresis. Thus, this work demonstrates the adaptability of the system to replace many common laboratory tasks on a single platform (through re-programmability, in rapid succession (using droplets

  9. Droplet centrifugation, droplet DNA extraction, and rapid droplet thermocycling for simpler and faster PCR assay using wire-guided manipulations.

    Science.gov (United States)

    You, David J; Yoon, Jeong-Yeol

    2012-01-01

    A computer numerical control (CNC) apparatus was used to perform droplet centrifugation, droplet DNA extraction, and rapid droplet thermocycling on a single superhydrophobic surface and a multi-chambered PCB heater. Droplets were manipulated using "wire-guided" method (a pipette tip was used in this study). This methodology can be easily adapted to existing commercial robotic pipetting system, while demonstrated added capabilities such as vibrational mixing, high-speed centrifuging of droplets, simple DNA extraction utilizing the hydrophobicity difference between the tip and the superhydrophobic surface, and rapid thermocycling with a moving droplet, all with wire-guided droplet manipulations on a superhydrophobic surface and a multi-chambered PCB heater (i.e., not on a 96-well plate). Serial dilutions were demonstrated for diluting sample matrix. Centrifuging was demonstrated by rotating a 10 μL droplet at 2300 round per minute, concentrating E. coli by more than 3-fold within 3 min. DNA extraction was demonstrated from E. coli sample utilizing the disposable pipette tip to cleverly attract the extracted DNA from the droplet residing on a superhydrophobic surface, which took less than 10 min. Following extraction, the 1500 bp sequence of Peptidase D from E. coli was amplified using rapid droplet thermocycling, which took 10 min for 30 cycles. The total assay time was 23 min, including droplet centrifugation, droplet DNA extraction and rapid droplet thermocycling. Evaporation from of 10 μL droplets was not significant during these procedures, since the longest time exposure to air and the vibrations was less than 5 min (during DNA extraction). The results of these sequentially executed processes were analyzed using gel electrophoresis. Thus, this work demonstrates the adaptability of the system to replace many common laboratory tasks on a single platform (through re-programmability), in rapid succession (using droplets), and with a high level of

  10. Centrifugal loop-mediated isothermal amplification microdevice for rapid, multiplex and colorimetric foodborne pathogen detection.

    Science.gov (United States)

    Oh, Seung Jun; Park, Byung Hyun; Jung, Jae Hwan; Choi, Goro; Lee, Doh C; Kim, Do Hyun; Seo, Tae Seok

    2016-01-15

    We present a centrifugal microfluidic device which enables multiplex foodborne pathogen identification by loop-mediated isothermal amplification (LAMP) and colorimetric detection using Eriochrome Black T (EBT). Five identical structures were designed in the centrifugal microfluidic system to perform the genetic analysis of 25 pathogen samples in a high-throughput manner. The sequential loading and aliquoting of the LAMP cocktail, the primer mixtures, and the DNA sample solutions were accomplished by the optimized zigzag-shaped microchannels and RPM control. We targeted three kinds of pathogenic bacteria (Escherichia coli O157:H7, Salmonella typhimurium and Vibrio parahaemolyticus) and detected the amplicons of the LAMP reaction by the EBT-mediated colorimetric method. For the limit-of-detection (LOD) test, we carried out the LAMP reaction on a chip with serially diluted DNA templates of E. coli O157:H7, and could observe the color change with 380 copies. The used primer sets in the LAMP reaction were specific only to the genomic DNA of E. coli O157:H7, enabling the on-chip selective, sensitive, and high-throughput pathogen identification with the naked eyes. The entire process was completed in 60min. Since the proposed microsystem does not require any bulky and expensive instrumentation for end-point detection, our microdevice would be adequate for point-of-care (POC) testing with high simplicity and high speed, providing an advanced genetic analysis microsystem for foodborne pathogen detection.

  11. Alternative separation steps for monoclonal antibody purification: combination of centrifugal partitioning chromatography and precipitation.

    Science.gov (United States)

    Oelmeier, Stefan A; Ladd-Effio, Christopher; Hubbuch, Jürgen

    2013-12-01

    Protein drugs continue to grow both in medicinal importance as in scale of their production. This furthers the interest in separation technologies that have the potential to replace chromatographic steps in a protein purification process. Two such unit operations that are employed in large scale in the chemical industry are extraction and precipitation. Their usefulness for the purification of proteins has been demonstrated, but the integration of such unit operations in a way that generate an output stream of high protein concentration and low process related impurities was missing. In this work, we employ centrifugal partitioning chromatography ('CPC') in combination with precipitation of the protein of interest to purify a cell culture supernatant of a monoclonal antibody producing cell line. Centrifugal partitioning chromatography was used as means of multi-step extraction using aqueous two-phase systems and was able to remove up to 88.2% of host cell protein ('HCP'). The following PEG driven precipitation and resolubilization of the protein of interest was use to condition the CPC output stream to suit subsequent chromatographic steps, to increase mAb concentration, remove the phase forming polymer, further improve HCP clearance, and integrate a low pH hold step for viral clearance. The entire process reduced HCP content by 99.4% while recovering 93% of the protein of interest. High throughput screening techniques were extensively employed during the development of the process.

  12. Centrifugal blood pump for temporary ventricular assist devices with low priming and ceramic bearings.

    Science.gov (United States)

    Leme, Juliana; da Silva, Cibele; Fonseca, Jeison; da Silva, Bruno Utiyama; Uebelhart, Beatriz; Biscegli, José F; Andrade, Aron

    2013-11-01

    A new model of centrifugal blood pump for temporary ventricular assist devices has been developed and evaluated. The design of the device is based on centrifugal pumping principles and the usage of ceramic bearings, resulting in a pump with reduced priming (35 ± 2 mL) that can be applied for up to 30 days. Computational fluid dynamic (CFD) analysis is an efficient tool to optimize flow path geometry, maximize hydraulic performance, and minimize shear stress, consequently decreasing hemolysis. Initial studies were conducted by analyzing flow behavior with different impellers, aiming to determine the best impeller design. After CFD studies, rapid prototyping technology was used for production of pump prototypes with three different impellers. In vitro experiments were performed with those prototypes, using a mock loop system composed of Tygon tubes, oxygenator, digital flow meter, pressure monitor, electronic driver, and adjustable clamp for flow control, filled with a solution (1/3 water, 1/3 glycerin, 1/3 alcohol) simulating blood viscosity and density. Flow-versus-pressure curves were obtained for rotational speeds of 1000, 1500, 2000, 2500, and 3000 rpm. As the next step, the CFD analysis and hydrodynamic performance results will be compared with the results of flow visualization studies and hemolysis tests.

  13. Experience in full-load testing of natural gas centrifugal compressors for rotordynamics improvements

    Energy Technology Data Exchange (ETDEWEB)

    Gelin, A.; Pugnet, J.M.; Bolusset, D.; Friez, P. [Framatome, Le Creusot (France)

    1997-10-01

    During full-load shop tests under natural gas, two multistage centrifugal compressors exhibited subsynchronous vibrations. Both of them are low-flow, high-pressure, high rotational speed compressors, and are fitted with tilting and bearings and dry gas seals. A rotating stall problem was first eliminated by a modification of the diffuser geometry. Then, aerodynamic excitations caused the rotors to operate at their stability limit, and high vibration levels were observed at the first natural frequency. A complete rotordynamics analysis was performed in order to model precisely all the fluid-structure interactions. Modifications of the rotor designs were implemented, consisting in optimizing conveniently the bearing pads, replacing the toothed labyrinth seals of the balance pistons by damping honeycomb seals, fitting them with improved shunt hole systems. In addition, the dry gas seals were found to have been damaged, due to thermal effects, and further modifications were implemented to eliminate this problem. Final full load tests demonstrated a satisfactory behavior of both centrifugal compressors.

  14. Identify the Rotating Stall in Centrifugal Compressors by Fractal Dimension in Reconstructed Phase Space

    Directory of Open Access Journals (Sweden)

    Le Wang

    2015-11-01

    Full Text Available Based on phase space reconstruction and fractal dynamics in nonlinear dynamics, a method is proposed to extract and analyze the dynamics of the rotating stall in the impeller of centrifugal compressor, and some numerical examples are given to verify the results as well. First, the rotating stall of an existing low speed centrifugal compressor (LSCC is numerically simulated, and the time series of pressure in the rotating stall is obtained at various locations near the impeller outlet. Then, the phase space reconstruction is applied to these pressure time series, and a low-dimensional dynamical system, which the dynamics properties are included in, is reconstructed. In phase space reconstruction, C–C method is used to obtain the key parameters, such as time delay and the embedding dimension of the reconstructed phase space. Further, the fractal characteristics of the rotating stall are analyzed in detail, and the fractal dimensions are given for some examples to measure the complexity of the flow in the post-rotating stall. The results show that the fractal structures could reveal the intrinsic dynamics of the rotating stall flow and could be considered as a characteristic to identify the rotating stall.

  15. Research on energy conversion mechanism of rotodynamic pump and design of non-overload centrifugal pump

    Science.gov (United States)

    Zhang, X. L.; Hu, S. B.; Shen, Z. Z.; Wu, S. P.; Li, K.

    2016-05-01

    In this paper, an attempt has been made for the calculation of an expression for the intrinsic law of input power which has not yet been given by current theory of Rotodynamic pump. By adequate recognition of the characteristics of non-inertial system within the rotating impeller, it is concluded that the input power consists of two power components, the first power component, whose magnitude increases with the increase of the flow rate, corresponds to radial velocity component, and the second power component, whose magnitude decreases with the increase of the flow rate, corresponds to tangential velocity component, therefore, the law of rise, basic levelness and drop of input power curves of centrifugal pump, mixed-flow pump and axial-flow pump can be explained reasonably. Through further analysis, the main ways for realizing non-overload of centrifugal pump are obtained, and its equivalent design factor is found out, the factor correlates with the outlet angle of leading face and back face of the blade, wrap angle, number of blades, outlet width, area ratio, and the ratio of operating flow rate to specified flow rate and so on. These are verified with actual example.

  16. Design optimization of a multi-blade centrifugal fan with Navier-Stokes analysis

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Seoung Jin; Kim, Kwang Yong [Inha Univ., Incheon (Korea, Republic of)

    2003-07-01

    In this paper, the response surface method using three-dimensional Navier-Stokes analysis to optimize the shape of a forward-curved blades centrifugal fan, is described. For numerical analysis, Reynolds-averaged Navier-Stokes equations with standard {kappa}-{epsilon} turbulence model are transformed into non-orthogonal curvilinear coordinate system, and are discretized with finite volume approximations. Due to the large number of blades in forward-curved blades centrifugal fan, the flow inside of the fan is regarded as steady flow by introducing the impeller force models for economic calculations. Linear Upwind Differencing Scheme(LUDS) is used to approximate the convection terms in the governing equations. SIMPLEC algorithm is used as a velocity-pressure correction procedure. Design variables, location of cur off, radius of cut off, expansion angle of scroll and width of impeller were selected to optimize the shapes of scroll and blades. Data points for response evaluations were selected by D-optimal design, and linear programming method was used for the optimization on the response surface. As a main result of the optimization, the efficiency was successfully improved. It was found that the optimization process provides reliable design of this kind of fans with reasonable computing time.

  17. Preparative Isolation of Polar Antioxidant Constituents from Abies koreana Using Centrifugal Partition Chromatography Guided by DPPH center dot-HPLC Experiment

    NARCIS (Netherlands)

    Jeon, Je-Seung; Kim, Ji Hoon; Park, Chae Lee; Kim, Chul Young

    2015-01-01

    Preparative separation of antioxidant constituents from the leaves of Abies koreana Wilson (Pinaceae) was performed by centrifugal partition chromatography (CPC) with a two-phase solvent system of ethyl acetate-isopropanol-water (9:1:10, v/v) target-guided by DPPH•-HPLC experiment. In DPPH•-HPLC exp

  18. Calibration of gyro error model coefficients on precision centrifuge with counter-rotating platform%《中国惯性技术学报》征稿简则

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    In order to accurately calibrate the gyro drift coefficients, a coordinate system was set up based on the precision centrifuge with counter-rotating platform, and the attitude relationship between two adjacent coordinate systems were analyzed in consideration of the error sources. Precise angular velocity input for each axis of gyro was derived by using direction cosine matrices, and the nominal value of each specific force input was given as well. Combined with the gyro's static error model, various harmonic amplitude expressions were deduced including gyro drift coefficients. By using centrifuge to provide two different harmonic accelerations, and sampling the output of gyro at each sampling time, the amplitudes of 0-2nd harmonics were obtained through Fourier analysis. The drift coefficients were identified by least square method based on the relationship between harmonic amplitude expressions and drift coefficients. The test simulation results show that the calibration of the gyro drift coefficients on centrifuge with counter-rotating platform can effectively avoid some of the centrifuge errors, and other centrifuge errors only have significant impacts on D1, Ds, DIO and DOs whose accurate calibration can be achieved by compensating the centrifuge errors.

  19. Distribution of centrifugal neurons targeting the soma clusters of the olfactory midbrain among decapod crustaceans.

    Science.gov (United States)

    Schmidt, M

    1997-03-28

    To determine the distribution of two systems of centrifugal neurons innervating the soma clusters of the olfactory midbrain across decapod crustaceans, brains of the following nine species comprising most infraorders were immunostained with antibodies against dopamine and the neuropeptides substance P and FMRFamide: Macrobrachium rosenbergii, Homarus americanus, Cherax destructor, Orconectes limosus, Procambarus clarkii, Astacus leptodactylus, Carcinus maenas, Eriocheir sinensis and Pagurus bernhardus. One system consisting of several neurons with dopamine-like immunoreactivity that originate in the eyestalk ganglia was present in the four crayfish but not in any other species. These neurons project mainly into the lateral soma clusters (cluster 10) comprising the somata of ascending olfactory projection neurons and innervate very sparsely the medial soma clusters (clusters 9 and 11) containing the somata of local interneurons. In the innervation pattern of the lateral cluster, the dopamine-immunoreactive neurons showed large species-specific differences. The other system comprises a pair of giant neurons with substance P-like immunoreactivity. These neurons have somata in the median protocerebrum of the central brain and major projections into the lateral clusters and the core of the olfactory lobes, the neuropils that are the first synaptic relay in the central olfactory pathway of decapods; minor arborizations are present in the medial clusters. The system of substance P-immunoreactive giant neurons was present and of great morphological similarity in all studied species. Only in one species, the shrimp Macrobrachium rosenbergii, evidence for co-localization of FMRFamide-like with substance P-like immunoreactivity in these neurons was obtained. These and previously collected data indicate that the centrifugal neurons with dopamine-like immunoreactivity may be associated with the presence of an accessory lobe, a second-order neuropil that receives input from the

  20. Influence of blade angle distribution along leading edge on cavitation performance of a centrifugal pump

    Science.gov (United States)

    Xu, Y.; Tan, L.; Cao, S. L.; Wang, Y. C.; Meng, G.; Qu, W. S.

    2015-01-01

    The influence of blade angle distribution along leading edge on cavitation performance of centrifugal pumps is analysed in the present paper. Three sets of blade angle distribution along leading edge for three blade inlet angles are chosen to design nine centrifugal pump impellers. The RNG k-epsilon turbulence model and the Zwart-Gerber-Belamri cavitation model are employed to simulate the cavitation flows in centrifugal pumps with different impellers and the same volute. The numerical results are compared with the experimental data, and the comparison proves that the numerical simulation can accurately predict the cavitation performance of centrifugal pumps. On the basis of the numerical simulations, the pump head variations with pump inlet pressure, and the flow details in centrifugal pump are revealed to demonstrate the influence of blade angle distribution along leading edge on cavitation performances of centrifugal pumps.