WorldWideScience

Sample records for centre vertical transmission

  1. Vertical Transmission of Babesia microti, United States

    OpenAIRE

    Joseph, Julie T.; Purtill, Kerry; Wong, Susan J.; Munoz, Jose; Teal, Allen; Madison-Antenucci, Susan; Horowitz, Harold W.; Aguero-Rosenfeld, Maria E.; Moore, Julie M.; Abramowsky, Carlos; Wormser, Gary P.

    2012-01-01

    Babesiosis is usually acquired from a tick bite or through a blood transfusion. We report a case of babesiosis in an infant for whom vertical transmission was suggested by evidence of Babesia spp. antibodies in the heel-stick blood sample and confirmed by detection of Babesia spp. DNA in placenta tissue.

  2. Determinants of Arbovirus Vertical Transmission in Mosquitoes.

    Directory of Open Access Journals (Sweden)

    Sebastian Lequime

    2016-05-01

    Full Text Available Vertical transmission (VT and horizontal transmission (HT of pathogens refer to parental and non-parental chains of host-to-host transmission. Combining HT with VT enlarges considerably the range of ecological conditions in which a pathogen can persist, but the factors governing the relative frequency of each transmission mode are poorly understood for pathogens with mixed-mode transmission. Elucidating these factors is particularly important for understanding the epidemiology of arthropod-borne viruses (arboviruses of public health significance. Arboviruses are primarily maintained by HT between arthropod vectors and vertebrate hosts in nature, but are occasionally transmitted vertically in the vector population from an infected female to her offspring, which is a proposed maintenance mechanism during adverse conditions for HT. Here, we review over a century of published primary literature on natural and experimental VT, which we previously assembled into large databases, to identify biological factors associated with the efficiency of arbovirus VT in mosquito vectors. Using a robust statistical framework, we highlight a suite of environmental, taxonomic, and physiological predictors of arbovirus VT. These novel insights contribute to refine our understanding of strategies employed by arboviruses to persist in the environment and cause substantial public health concern. They also provide hypotheses on the biological processes underlying the relative VT frequency for pathogens with mixed-mode transmission that can be tested empirically.

  3. Medical data transmission system for remote healthcare centres

    International Nuclear Information System (INIS)

    The main motivation of this project is to improve the healthcare centres equipment and human resources efficiency, enabling those centres for transmission of parameters of medical interest. This system facilitates remote consultation, in particular between specialists and remote healthcare centres. Likewise it contributes to the qualification of professionals. The electrocardiographic (ECG) and electroencephalographic (EEG) signals are acquired, processed and then sent, fulfilling the effective norms, for application in the hospital network of Cordoba Province, which has nodes interconnected by phone line. As innovative aspects we emphasized the low cost of development and maintenance, great versatility and handling simplicity with a modular design for interconnection with diverse data transmission media (Wi-Fi, GPRS, etc.). Successfully experiences were obtained during the acquisition of the signals and transmissions on wired LAN networks. As improvements, we can mention: energy consumption optimization and mobile communication systems usage, in order to offer more autonomy

  4. Vertical transmission of Toxoplasma gondii in Australian marsupials

    OpenAIRE

    Parameswaran, N.; O’Handley, R.M.; Grigg, M. E.; Wayne, A.; Thompson, R.C.A.

    2009-01-01

    To date, little is known about the dynamics of vertical transmission of Toxoplasma gondii in Australian marsupials. Studies in mice demonstrate that vertical transmission of T. gondii is common and that chronically infected mice can transmit T. gondii to successive generations. In this study, PCR and immunohistochemistry were used to detect T. gondii in chronically infected marsupial dams and their offspring. T. gondii was detected in the unfurred pouch young of 2 out of 10 chronically infect...

  5. Vertical transmission of consumption behavior and the distribution of surnames

    OpenAIRE

    Collado, M. Dolores; Ortuño Ortin, Ignacio; Romeu, Andrés

    2006-01-01

    This paper attempts to detect the existence of links in consumption preferences between generations. Preferences for consumption goods may be determined by the preferences of parents (vertical transmission) and/or by preferences arising from the environment (horizontal transmission). We propose an indirect methodology to overcome the lack of data on consumption choices of dynasties, i.e., parents and their adult offspring. This new approach is based on the analysis of the correlation between ...

  6. WAVE TRANSMISSION AND REFLECTION DUE TO A THIN VERTICAL BARRIER

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A numerical method, the boundary fitted coordinate method (BFC),was used to investigate the transmission and reflection of water waves due to a rigid thin vertical barrier descending from the water surface to a depth, i. e. , a curtain-wall type breakwater. A comparison between the present computed results and previous experimental and analytical results was carried out which verifies the prediction of the BFC method. Wave transmission and reflection due to the barrier were computed, and the transmission and refiection coefficients were given in a figure.

  7. Vertical transmission of hepatitis C virus: Current knowledge and perspectives

    Institute of Scientific and Technical Information of China (English)

    Chun-Yan; Yeung; Hung-Chang; Lee; Wai-Tao; Chan; Chun-Bin; Jiang; Szu-Wen; Chang; Chih-Kuang; Chuang

    2014-01-01

    Hepatitis C virus(HCV) infection is a major global health issue.Infection by the HCV can cause acute and chronic liver diseases and may lead to cirrhosis,hepatocellular carcinoma or liver failure.The World Health Organization estimates that approximately 3% of the world population have been infected with HCVand the worldwide prevalence is between 1% and 8% in pregnant women and between 0.05% and 5% in children.Following the introduction of blood product screening,vertical transmission becomes the leading cause of childhood HCV infection.The prevalence of pediatric HCV infection varies from 0.05% to 0.36% in developed countries and between 1.8% and 5% in the developing world.All children born to women with antiHCV antibodies should be checked for HCV infection.Though universal screening is controversial,selective antenatal HCV screening on high-risk populations is highly recommended and should be tested probably.Multiple risk factors were shown to increase the possibility of HCV vertical transmission,including coinfections with human immunodeficiency virus,intravenous drug use and elevated maternal HCV viral load,while breastfeeding and HCV genotypes have been studied to have little impact.At present,no clinical intervention has been clearly studied and proved to reduce the HCV vertical transmission risk.Cesarean section should not be recommended as a procedure to prevent vertical transmission,however,breastfeeding is generally not forbidden.The high prevalence of global HCV infection necessitates renewed efforts in primary prevention,including vaccine development,as well as new approaches to reduce the burden of chronic liver disease.Future researches should focus on the interruption of vertical transmission,developments of HCV vaccine and directacting antivirals in infancy and early childhood.

  8. Intrapartum practices to limit vertical transmission of HIV.

    Science.gov (United States)

    du Preez, Antoinette; du Plessis, Engela; Pienaar, Abel

    2006-09-01

    The need to improve health services to HIV-positive women requires a specific focus on limiting mother-to-child transmission. Vertical transmission most often takes place during the intrapartum period; hence, it is essential to alert midwives to what constitutes safe or risky intrapartum practices. Midwives in the southern region of the North West Province of South Africa were surveyed for their knowledge of safe intrapartum practices that can limit vertical transmission of HIV, consequently indicating which intrapartum practices prevail in the region. We used a quantitative survey design and collected data by means of a questionnaire and checklist. A purposeful availability sample of 31 midwives who work in all four hospitals in the province was used and a random sample of 401 obstetric records was audited. Data were analysed by means of frequency analysis, effect sizes and cross-reference. A slight majority of the midwives had sufficient knowledge to distinguish between risky and safe practices. However, safe intrapartum practices are not always carried out and this raises concerns. Accordingly, we formulate general recommendations for nursing education, future research, and midwifery practice. In particular we suggest ways the national Guidelines for Maternity Care in South Africa may be adapted and better implemented to enhance safe intrapartum practices to limit vertical transmission of HIV. PMID:25875244

  9. Improving dimensional accuracy by error modelling and its compensation for 3-axis Vertical Machining Centre

    OpenAIRE

    Dobariya, H. M.; Patel, Y D; Jani, D. A.

    2015-01-01

    In today’s era, machining centres are very important units of manufacturing systems. Due to the structural characteristics, inaccuracy of the tool tip position is inherent. This could be a result of geometric error, thermal error, fixture dependant error and cutting force induced error. The geometric error contributes 70% of the total errors related to a machine tool. Present work focuses on improving dimensional accuracy of a 3-axis vertical machining centre (VMC). Accurate e...

  10. Evidence for Vertical Transmission of HPV from Mothers to Infants

    Directory of Open Access Journals (Sweden)

    Elaine M. Smith

    2010-01-01

    Full Text Available Few large studies have evaluated concordance based on a broad spectrum of human papillomavirus (HPV types in oral and genital specimens of mothers and their recently born infants. This information is important in determining whether HPV vaccines administered prior to pregnancy may be useful for preventing vertical transmission. HPV DNA was positive in 30% of mothers and 1.5% of newborns. Maternal/newborn concordance (HPV+/+ or HPV−/− was 71%. Among HPV DNA+ mothers, only 3% of their infants were DNA+ and only 1 pair had the same HPV type. Among HPV− women, 0.8% of infants were HPV+. HPV DNA detected in hospitalized newborns reflects current infection transmitted to infants during pregnancy or delivery. None of the mother/baby HPV DNA+ concordance pairs detected viral types found in HPV vaccines suggesting that vaccination prior to pregnancy is unlikely to be efficacious in preventing vertical transmission.

  11. Vertical transmission of nucleopolyhedrovirus in the silkworm, Bombyx mori L.

    Science.gov (United States)

    Khurad, A M; Mahulikar, A; Rathod, M K; Rai, M M; Kanginakudru, S; Nagaraju, J

    2004-09-01

    Nucleopolyhedrovirus (NPV) was tested for vertical transmission in the silkworm, Bombyx mori. Fifth instar larvae were exposed to four different dosages of BmNPV (830, 1300, 1800, and 2000OBs/larva) and a dosage of about 2000OBs/larva was found suitable for obtaining infected adults. Histopathological studies revealed the infection in susceptible tissues and organs initially, and at later stages of infection cycles the spermatocytes and nurse cells in the young oocytes were infected in the larval rudiments of testis and ovary, respectively. The mating of infected females with uninfected males resulted in significant reduction in fecundity (P < 0.01) and hatching of eggs (P < 0.001) due to transovarial transmission of BmNPV. Mating tests of uninfected females and infected males also confirmed venereal transmission as there was a significant reduction in hatching of eggs (P < 0.01). Further, among the F1 hybrid offspring (infected female x uninfected male) that were infected transovarially, larval progeny died at first and second instar stages, whereas those infected venereally developed acute lethal infection late and died by the end of third and fourth instar stage. PCR amplification and sequencing of 473bp of immediate early-1 (ie-1) gene of BmNPV isolated from the viral-infected parent and the F1 offspring confirmed that the viral infection is vertically transmitted to the progeny. PMID:15491594

  12. Diverse strategies for vertical symbiont transmission among subsocial stinkbugs.

    Directory of Open Access Journals (Sweden)

    Takahiro Hosokawa

    Full Text Available Sociality may affect symbiosis and vice versa. Many plant-sucking stinkbugs harbor mutualistic bacterial symbionts in the midgut. In the superfamily Pentatomoidea, adult females excrete symbiont-containing materials from the anus, which their offspring ingest orally and establish vertical symbiont transmission. In many stinkbug families whose members are mostly non-social, females excrete symbiont-containing materials onto/beside eggs upon oviposition. However, exceptional cases have been reported from two subsocial species representing the closely related families Cydnidae and Parastrachiidae, wherein females remain nearby eggs for maternal care after oviposition, and provide their offspring with symbiont-containing secretions at later stages, either just before or after hatching. These observations suggested that sociality of the host stinkbugs may be correlated with their symbiont transmission strategies. However, we found that cydnid stinkbugs of the genus Adomerus, which are associated with gammaproteobacterial gut symbionts and exhibit elaborate maternal care over their offspring, smear symbiont-containing secretions onto eggs upon oviposition as many non-social stinkbugs do. Surface sterilization of the eggs resulted in aposymbiotic insects of slower growth, smaller size and abnormal body coloration, indicating vertical symbiont transmission via egg surface contamination and presumable beneficial nature of the symbiosis. The Adomerus symbionts exhibited AT-biased nucleotide compositions, accelerated molecular evolutionary rates and reduced genome size, while these degenerative genomic traits were less severe than those in the symbiont of a subsocial parastrachiid. These results suggest that not only sociality but also other ecological and evolutionary aspects of the host stinkbugs, including the host-symbiont co-evolutionary history, may have substantially affected their symbiont transmission strategies.

  13. Vertical hepatitis C virus transmission:Main questions and answers

    Institute of Scientific and Technical Information of China (English)

    Grazia; Tosone; Alberto; Enrico; Maraolo; Silvia; Mascolo; Giulia; Palmiero; Orsola; Tambaro; Raffaele; Orlando

    2014-01-01

    Hepatitis C virus(HCV) affects about 3% of the world’s population and peaks in subjects aged over 40 years. Its prevalence in pregnant women is low(1%-2%) in most western countries but drastically increases in women in developing countries or with high risk behav-iors for blood-transmitted infections. Here we review clinical, prognostic and therapeutic aspects of HCV in-fection in pregnant women and their offspring infected through vertical transmission. Pregnancy-related im-mune weakness does not seem to affect the course of acute hepatitis C but can affect the progression of chronic hepatitis C. In fact, postpartum immune res-toration can exacerbate hepatic inflammation, thereby worsening the liver disease, particularly in patients with liver cirrhosis. HCV infection increases the risk of gestational diabetes in patients with excessive weight gain, premature rupture of membrane and caesarean delivery. Only 3%-5% of infants born to HCV-positive mothers have been infected by intrauterine or perinatal transmission. Maternal viral load, human immunode-ficiency virus coinfection, prolonged rupture of mem-branes, fetal exposure to maternal infected blood con-sequent to vaginal or perineal lacerations and invasive monitoring of fetus increase the risk of viral transmis-sion. Cesarean delivery and breastfeeding increases the transmission risk in HCV/human immunodeficiency virus coinfected women. The consensus is not to offer antivi-ral therapy to HCV-infected pregnant women because it is based on ribavirin(pregnancy category X) because of its embryocidal and teratogenic effects in animal spe-cies. In vertically infected children, chronic C hepatitis is often associated with minimal or mild liver disease and progression to liver cirrhosis and hepatocarcinoma is lower than in adults. Infected children may be treated after the second year of life, given the adverse effects of current antiviral agents.

  14. CLINICAL OBSERVATION ON VERTICAL TRANSMISSION OF HUMAN PAPILLOMAVIRUS

    Institute of Scientific and Technical Information of China (English)

    徐倏燊; 刘兰青; 吕绳敏; 任舒月

    1998-01-01

    Objective. To observe the possibility of maternal-fetal vertical transmission of human papillomavirus (HPV)via amniotic fluid. Subjects and methods. Specimens of cervical secretions from 30 pregnant women were obtained during the third trimester before rupture of membrane, and specimens of pharyngeal secretsions of their neonates weee obtained 12-48 h after birth. Amniotic fluids were collected in 13 pregnant women during cesarean section. The presence of HPV types 6,11,16,18,31,33,35,38 deoxyribonucleic acid were detected by consensus polymerase chain reaction. Remits. HPV deoxyribonucleic acid was found in 18 cervical secretions, 14 pharyngeal secretions and in 8 amniotic fluids, the positive rate was 53. 3%, 46.7%, 23. 1% respectively. The pharyngeal secretion was also HPV positive in one of the three neonates from the amnlotic fluid positive mothers. Conclusion. The results indic.am that HPV can be transmitted in utezo through amniotic fluid and cesarean section can not protect the neonates against vertical transmission completely.

  15. Expanding the role of community mobilization to accelerate progress towards ending vertical transmission of HIV in Uganda: the Networks model

    Directory of Open Access Journals (Sweden)

    Kate Iorpenda

    2012-07-01

    health and prevention of vertical HIV transmission. Conclusions: By placing persons living with HIV at the centre, the Networks model offers a mechanism for strengthening community and male involvement in preventing vertical transmission of HIV. The role of communities and networks of people living with HIV in planning, service delivery and monitoring of national targets for prevention of vertical transmission should be further strengthened through greater community engagement in service delivery and advocacy and through the regular sharing of data between communities and health facilities.

  16. Integrated Geometric Errors Simulation, Measurement and Compensation of Vertical Machining Centres

    OpenAIRE

    Gohel, C.K.; Makwana, A.H.

    2014-01-01

    This Paper presents research on geometric errors of simulated geometry which are measured and compensate in vertical machining centres. There are many errors in CNC machine tools have effect on the accuracy and repeatability of manufacture. Most of these errors are based on specific parameters such as the strength and the stress, the dimensional deviations of the structure of the machine tool, thermal variations, cutting force induced errors and tool wear. In this paper machining system that ...

  17. Possible Vertical Transmission of Bartonella bacilliformis in Peru

    Science.gov (United States)

    Tuya, Ximena L.; Escalante-Kanashiro, Raffo; Tinco, Carmen; Pons, Maria J.; Petrozzi, Verónica; Ruiz, Joaquim; del Valle, Juana

    2015-01-01

    A 22-day-old male was admitted with a 2-day history of irritability, dyspnea, jaundice, fever, and gastrointestinal bleeding. A thin blood smear was performed, which showed the presence of intraerythrocyte bacteria identified as Bartonella bacilliformis, and subsequently, the child was diagnosed with Carrion's disease. The diagnosis was confirmed by specific polymerase chain reaction. The child was born in a non-endemic B. bacilliformis area and had not traveled to such an area before hospitalization. However, the mother was from an endemic B. bacilliformis area, and posterior physical examination showed the presence of a wart compatible with B. bacilliformis in semi-immune subjects. These data support vertical transmission of B. bacilliformis. PMID:25371184

  18. Transmission of vertical stress in a real soil profile. Part III

    DEFF Research Database (Denmark)

    Lamandé, Mathieu; Schjønning, Per

    2011-01-01

    dry/dry, respectively). The Söhne model underestimated the vertical stresses at all depths, and the model fit was poorest at low water contents. Our data thus support the general characteristics of the elasticity theory, although the simple one-layer Söhne model gave poor quantitative stress......The transmission of stress in soils is extremely sensitive to changes in water content. According to the elasticity theory, for a given load applied to a given soil, an increase in soil water content yields a higher concentration of stresses under the centre of the load and a deeper propagation of...... stresses. We quantified the effect of soil water content of topsoil/subsoil layers (wet/wet, wet/dry, and dry/dry) on stress transmission. 3D measurements of vertical stresses under a towed wheel (800/50R34) were performed in situ in a Stagnic Luvisol. The tyre was loaded with 60 kN, and we used the...

  19. Estimation of hepatitis C virus infections resulting from vertical transmission in Egypt

    OpenAIRE

    Benova, Lenka; Awad, Susanne F.; Miller, F. DeWolfe; Abu-Raddad, Laith J

    2015-01-01

    Despite having the highest hepatitis C virus (HCV) prevalence in the world, the ongoing level of HCV incidence in Egypt and its drivers are poorly understood. Whereas HCV mother-to-child infection is a well-established transmission route, there are no estimates of HCV infections resulting from vertical transmission for any country, including Egypt. The aim of this study was to estimate the absolute number of new HCV infections resulting from vertical transmission in Egypt. We developed a conc...

  20. Vertical price transmission analysis: The case of milk in the slovak dairy sector

    OpenAIRE

    Lajdová, Zuzana; Bielik, Peter

    2013-01-01

    Testing for nature price transmission and calculating elasticities of price transmission are important areas of research for providing insights into market efficiency issues. Symmetric or asymmetric price transmission has been the subject of considerable attention in agricultural economics. The concept of the price transmission is an important area of the research particularly in relation to the assessment of impact on the welfare of the vertical entities. The main goal of the paper is an ana...

  1. Natural vertical transmission by Stegomyia albopicta as dengue vector in Brazil Transmissão vertical natural de Stegomyia albopicta como vetor de dengue no Brasil

    OpenAIRE

    AB. Cecílio; ES. Campanelli; KPR. Souza; LB. Figueiredo; MC. Resende

    2009-01-01

    The mosquito Stegomyia albopicta is among the most important arbovirus vectors in the world, particularly for Dengue viruses. Their natural history suggests that biologically these viruses are highly adapted to their mosquito hosts and they were most likely mosquito viruses prior to becoming adapted to lower primates and humans. As well as being maintained by transmission among susceptible humans, Dengue viruses may also be maintained by vertical transmission in mosquitoes during inter-epidem...

  2. Similar sponge-associated bacteria can be acquired via both vertical and horizontal transmission

    DEFF Research Database (Denmark)

    Sipkema, Detmer; de Caralt, Sònia; Morillo, Jose A;

    2015-01-01

    Marine sponges host diverse communities of microorganisms that are often vertically transmitted from mother to oocyte or embryo. Horizontal transmission has often been proposed to co-occur in marine sponges, but the mechanism is poorly understood. To assess the impact of the mode of transmission on...... the microbial assemblages of sponges, we analysed the microbiota in sympatric sponges that have previously been reported to acquire bacteria via either vertical (Corticium candelabrum and Crambe crambe) or horizontal transmission (Petrosia ficiformis). The comparative study was performed by PCR...... very different phylogenetic signature. In addition, nearly 50% of the reads obtained from P. ficiformis were most closely related to bacteria that were previously reported to be vertically transmitted in other sponges and comprised vertical-horizontal transmission phylogenetic clusters (VHT clusters...

  3. Vertical price transmission in the Danish food chain

    DEFF Research Database (Denmark)

    Jensen, Jørgen Dejgård; Møller, Anja Skadkær

    2005-01-01

    This purpose of this paper is to investigate price transmission patterns through selected Danish food chains – from primary production to processing, from processing to wholesale and from wholesale to retail prices. Specifically, the study addresses the following research questions: To what exten...... between sectors and stages of the food supply chain. Both transaction costs and imperfect competition seem to contribute to these asymmetries....... are commodity prices transmitted from one stage to another in the food chain? What is the time horizon in the price transmission? Is price transmission symmetric – in the short run and in the long run? Is the degree of price transmission affected by the degree of concentration in the supply and demand...

  4. Comparative analysis of Streptococcus pneumoniae transmission in Portuguese and Finnish day-care centres

    OpenAIRE

    Pessoa, Delphine; Hoti, Fabian; Syrjänen, Ritva; Sá-Leão, Raquel; Kaijalainen, Tarja; Gomes, M. Gabriela M.; Auranen, Kari

    2013-01-01

    Day-care centre (DCC) attendees play a central role in maintaining the circulation of Streptococcus pneumoniae (pneumococcus) in the population. The prevalence of pneumococcal carriage is highest in DCC attendees but varies across countries and is found to be consistently lower in Finland than in Portugal. We compared key parameters underlying pneumococcal transmission in DCCs to understand which of these contributed to the observed differences in carriage prevalence. PneumoCarr Consortium...

  5. Comparative analysis of Streptococcus pneumoniae transmission in Portuguese and Finnish day-care centres

    OpenAIRE

    Pessoa, Delphine; Hoti, Fabian; Syrjänen, Ritva; Sá-Leão, Raquel; Kaijalainen, Tarja; Gomes, M. Gabriela M.; Auranen, Kari

    2013-01-01

    Background Day-care centre (DCC) attendees play a central role in maintaining the circulation of Streptococcus pneumoniae (pneumococcus) in the population. The prevalence of pneumococcal carriage is highest in DCC attendees but varies across countries and is found to be consistently lower in Finland than in Portugal. We compared key parameters underlying pneumococcal transmission in DCCs to understand which of these contributed to the observed differences in carriage prevalence. Methods Longi...

  6. Biofuels and Vertical Price Transmission: The Case of the US Corn, Ethanol, and Food Markets

    NARCIS (Netherlands)

    Drabik, D.; Ciaian, P.; Pokrivcak, J.

    2014-01-01

    This is the first paper to analyze the impact of biofuels on the price transmission along the food chain. We analyze the U.S. corn sector and its vertical links with food and ethanol (energy) markets. We find that biofuels affect the price transmission elasticity in the food chain compared to a no b

  7. Discrepancy in impact of maternal milk on vertical transmission between Hepatitis B virus and Human cytomegalovirus

    Directory of Open Access Journals (Sweden)

    Ting Wang

    2015-08-01

    Conclusions: Breastfeeding is not a risk factor for maternal-to-infant transmission of HBV after the recommended prophylaxis is implemented. However, viral DNA positive breast milk is a main source for vertical transmission of HCMV to infants who are not protected by a standard immunoprophylaxis protocol.

  8. Economic Issues in the Prevention of Vertical Transmission of HIV

    OpenAIRE

    Ades, A. E.; Julie Ratcliffe; Gibb, Diana M.; Sculpher, Mark J.

    2000-01-01

    In the absence of interventions, 20% of infants born to women infected with HIV acquire infection from their mother at or before delivery. A further 15% are infected through breast feeding. Prenatal testing for HIV allows infected women to be reliably identified so that they can receive antiretroviral therapy and, in countries with safe water supplies, be advised not to breast feed. These and other interventions can reduce the risk of transmission to 5% or less. Economic evaluations of prenat...

  9. Effectiveness of the prevention of mother-to-child transmission of HIV protocol applied at Saint Camille Medical Centre in Ouagadougou, Burkina Faso

    Directory of Open Access Journals (Sweden)

    Serge Theophile Soubeiga

    2014-11-01

    Full Text Available Introduction: Despite many prevention efforts, the number of children infected by HIV in sub-Saharan Africa through vertical transmission remains high. This infection can be reduced through programmes of prevention of mother-to-child HIV transmission (PMTCT. The objective of this study was to evaluate the effectiveness of the PMTCT protocol at Saint Camille Medical Centre in Ouagadougou, Burkina Faso. Methods: From August 2012 to September 2013, samples of dried blood spot (DBS were collected from 160 children aged 6 weeks born to HIV-1 positive mothers who were under PMTCT protocol at Saint Camille Medical Centre and 40 children of the same age group from orphanages and whose mothers were dead or unknown. The samples were tested using the Abbott Real Time HIV-1 Qualitative kit. The clinical data of mothers were collected and analyzed using SPSS Version 17.0 and Epi Info Version 6.0 softwares. Results: Among pregnant women in this study, 52.5% were predominantly young (24–29 years and 60.62% were housewives. In total, 50.5% (101/200 were in combination of AZT/3TC/NVP and 29.5% (59/200 were on prophylaxis (AZT/3TC. The rate of vertical transmission of HIV-1 was 0.0% (p<0.001 in children whose mothers were taking a combination of AZT/3TC/NVP (0/101 or were on a prophylaxis AZT/3TC treatment (0 /59. The rate of HIV-1 transmission in orphaned children was 15.0% (6/40. Conclusions: The PMTCT protocol is effective and reduces very significantly (p<0.001 the risk of transmission of HIV-1 from mother to child. In addition, screening by PCR of orphaned children vertically infected with HIV, enabled them to receive an early treatment.

  10. ZIKA VIRUS INFECTION; VERTICAL TRANSMISSION AND FOETAL CONGENITAL ANOMALIES.

    Science.gov (United States)

    Abbasi, Aziz-un-Nisa

    2016-01-01

    Zika virus (ZIKV) is an arbovirus belonging to flaviviridae family that includes Dengue, West Nile, and Yellow Fever among others. Zika virus was first discovered in 1947 in Zika forest of Uganda. It is a vector borne disease, which has been sporadically reported mostly from Africa, Pacific islands and Southeast Asia since its discovery. ZIKV infection presents as a mild illness with symptoms lasting for several days to a week after the bite of an infected mosquito. Majority of the patients have low grade fever, rash, headaches, joints pain, myalgia, and flu like symptoms. Pregnant women are more vulnerable to ZIKV infection and serious congenital anomalies can occur in foetus through trans-placental transmission. The gestation at which infection is acquired is important. Zika virus infection acquired in early pregnancy poses greater risk. There is no evidence so far about transmission through breast milk. Foetal microcephaly, Gillian Barre syndrome and other neurological and autoimmune syndromes have been reported in areas where Zika outbreaks have occurred. As infection is usually very mild no specific treatment is required. Pregnant women may be advised to take rest, get plenty of fluids. For fever and pain they can take antipyretics like paracetamol. So far no specific drugs or vaccines are available against Zika Virus Infection so prevention is the mainstay against this diseases. As ZIKV infection is a vector borne disease, prevention can be a multi-pronged strategy. These entail vector control interventions, personal protection, environmental sanitation and health education among others. PMID:27323550

  11. Prevention of vertical transmission of HIV in Denmark

    DEFF Research Database (Denmark)

    Rasmussen, M.B.; Rasmussen, J.B.; Nielsen, V.R.;

    2008-01-01

    during the study period. In 79% of the cases, the woman knew her HIV status at the beginning of her pregnancy. The median CD4 count before delivery was 447 x 10(6)/l, and in 76% of the cases the HIV-RNA was < 20 copies/ml. 88% of the women delivered by Caesarean section. None of the children were...... breastfed. None of the children were infected during pregnancy, delivery or after birth. During the same period of time, 8 children were diagnosed with HIV in Denmark; they were born to mothers whose HIV infection was not diagnosed during pregnancy or delivery and therefore preventive treatment was not...... initiated. CONCLUSION: As long as preventive treatment strategies are followed, there is no transmission of HIV from mother to child, neither during pregnancy nor during or after birth Udgivelsesdato: 2008/8/18...

  12. Global dynamics behaviors for new delay SEIR epidemic disease model with vertical transmission and pulse vaccination

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    A robust SEIR epidemic disease model with a profitless delay and vertical transmission is formulated, and the dynamics behaviors of the model under pulse vaccination are analyzed.By use of the discrete dynamical system determined by the the model are under appropriate conditions.Using the theory on delay functional and impulsive differential equation, the sufficient condition with time delay for the permanence of the system is obtained, and it is proved that time delays, pulse vaccination and vertical transmission can bring obvious effects on the dynamics behaviors of the model.

  13. How Important is Vertical Transmission of Dengue Viruses by Mosquitoes (Diptera: Culicidae)?

    Science.gov (United States)

    Grunnill, Martin; Boots, Michael

    2016-01-01

    Vertical transmission of dengue viruses by mosquitoes was discovered at the end of the late 1970s and has been suggested to be a means by which these viruses persist. However, it is unclear how widespread it is in nature, and its importance in the epidemiology of this disease is still debated. Here, we review the literature on vertical transmission and discuss its role in dengue's epidemiology and control. We conclude that given the number of studies that failed to find evidence of vertical transmission, as well as mathematical models and its mechanistic basis, it is unlikely that vertical transmission is important for the epidemiological persistence of dengue viruses. A combination of asymptomatic infection in humans and movement of people are likely to be more important determinants of dengue's persistence. We argue, however, that there may be some need for further research into the prevalence of dengue viruses in desiccated, as well as diapausing, eggs and the role of horizontal transmission through larval cannibalism. PMID:26545718

  14. Influence of equinus treatments on the vertical displacement of the body's centre of mass in children with cerebral palsy.

    Science.gov (United States)

    Massaad, Firas; van den Hecke, Adélaïde; Renders, Anne; Detrembleur, Christine

    2006-10-01

    We assessed the influence of equinus gait treatments on the vertical displacement of the body's centre of mass (COM) in 21 patients with cerebral palsy (14 males, 7 females; mean age 8 y 9 mo [SD 2 y]; range 3 y 7 mo-17 y) presenting different topographical types (quadriplegia, n = 1; diplegia, n = 6; right hemiplegia, n = 6; and left hemiplegia, n = 8). Vertical COM displacement was computed from ground reaction forces, and lower limb kinematics was recorded simultaneously. Equinus gait was treated with non-operative treatments (i.e. botulinum toxin injections and stretching casts) in 14 patients, and with operative treatments in seven patients. After non-operative treatments, the entire ankle displacement shifted towards dorsiflexion throughout the gait cycle, but the amplitude of the third foot rocker (TR) and vertical COM displacement remained unchanged. However, after operative treatments, the amplitude of TR increased and vertical COM displacement decreased. A negative linear correlation was found between the former variables in all the patients where 53% of the changes in their vertical COM displacement, after equinus gait treatments, were explained by the changes in TR amplitude. In fact, TR remains a main gait determinant, reducing the vertical COM displacement after equinus gait treatment and influencing the general gait pattern. PMID:16978460

  15. Study on the risk factors related vertical transmission of HBV positive couples to their infant

    Institute of Scientific and Technical Information of China (English)

    张荣莲

    2013-01-01

    Objective To explore the risk factors and the rate of HBV vertical transmission from HBsAg-positive couple to their infant. Methods 46 families who had antenatal examination at Fujian Provincial Maternal and Child Health Hospital during August 2010 and November 2011 were

  16. Fatores protetores e de risco envolvidos na transmissão vertical do HIV-1 Protective and risk factors related to vertical transmission of the HIV-1

    Directory of Open Access Journals (Sweden)

    Rosângela P. Gianvecchio

    2005-04-01

    Full Text Available Este estudo avalia os fatores maternos e fetais envolvidos na transmissão vertical do HIV-1 em 47 pares de mãe e filho. As variáveis comportamentais, demográficas e obstétricas foram obtidas mediante entrevista; os dados referentes ao parto e ao recém-nascido, dos prontuários das maternidades. Durante o terceiro trimestre de gestação foi realizada a contagem da carga viral materna e dos linfócitos T CD4+. A média de idade foi de 25 anos e 23,4% das gestantes eram primigestas, e o fator comportamental mais prevalente foi não usar preservativos. Dentre as gestantes, 48,9% tinham células CD4+ superior a 500 células/mm³ e 93,6% se enquadravam na categoria clínica A; 95,7% submeteram-se à profilaxia com zidovudina durante a gestação ou no parto, a qual foi ministrada a todos os recém-nascidos; 50,0% delas foram submetidas à cesárea eletiva. Apesar de expostas a vários fatores de risco e protetores, nenhuma criança tornou-se infectada. A transmissão vertical resulta de um desequilíbrio entre os fatores, com predomínio dos de risco sobre os protetores.This study aimed to evaluate maternal and fetal factors related to vertical transmission of HIV-1. Participants included 47 mother-child pairs. Behavioral, demographic, and obstetric data were obtained through interviews. Data related to delivery and newborns were collected from registries in the maternity hospitals. During the third trimester of pregnancy, CD4+ T lymphocytes and maternal viral load were measured. Mean age of the mothers was 25 years and 23.4% of the pregnant women were primigravidae. The most prevalent behavioral factor was lack of condom use. 48.9% of the women presented a CD4+ count greater than 500 cells/ mm³, and 93.6% belonged to clinical category A. 95.7% of the women received zidovudine prophylaxis during pregnancy or childbirth, and the medication was also administered to all the neonates. 50.0% of patients were submitted to elective cesareans. Despite

  17. Asymptomatic Genital Infection of Human Papillomavirus in Pregnant Women and the Vertical Transmission Route

    Institute of Scientific and Technical Information of China (English)

    DENG Dongrui; WEN Liangzhen; CHEN Wen; LING Xiazhen

    2005-01-01

    Summary: To further investigate the vertical transmission route of human papillomavirus (HPV) and the indication for the choice of mode of delivery, the infective status of 152 asymptomatic pregnant wemen and the maternal-fetal transmission were studied. By using general primers in polymerase chain reaction (GP-PCR) combined with restriction fragment length polymorphism analysis, HPV DNA positive rate in cervical secretions and venous blood in asymptomatic pregnant women was 36.21 % and 52.78 %, respectively, and the identified genotypes were mainly HPV16 and 18. The maternal-fetal transmission rate of HPV via genital tract as well as blood was 40.91 % and 57.89 %, respectively. It was concluded that besides the transmission route of genital tract and amniotic fluid, there was also transplacental transmission of HPV in utero. Therefore,in our opinion, it is not an absolut indication to perform a cesarean delivery for the pregnant women with HPV asymtomatic genital infection.

  18. Vertical human immunodeficiency virus type 1 - HIV-1 -transmission - a review

    Directory of Open Access Journals (Sweden)

    Vera Bongertz

    2001-01-01

    Full Text Available Several factors appear to affect vertical HIV-1 transmission, dependent mainly on characteristics of the mother (extent of immunodeficiency, co-infections, risk behaviour, nutritional status, immune response, genetical make-up, but also of the virus (phenotype, tropism and, possibly, of the child (genetical make-up. This complex situation is compounded by the fact that the virus may have the whole gestation period, apart from variable periods between membrane rupture and birth and the breast-feeding period, to pass from the mother to the infant. It seems probable that an extensive interplay of all factors occurs, and that some factors may be more important during specific periods and other factors in other periods. Factors predominant in protection against in utero transmission may be less important for peri-natal transmission, and probably quite different from those that predominantly affect transmission by mothers milk. For instance, cytotoxic T lymphocytes will probably be unable to exert any effect during breast-feeding, while neutralizing antibodies will be unable to protect transmission by HIV transmitted through infected cells. Furthermore, some responses may be capable of controlling transmission of determined virus types, while being inadequate for controlling others. As occurence of mixed infections and recombination of HIV-1 types is a known fact, it does not appear possible to prevent vertical HIV-1 transmission by reinforcing just one of the factors, and probably a general strategy including all known factors must be used. Recent reports have brought information on vertical HIV-1 transmission in a variety of research fields, which will have to be considered in conjunction as background for specific studies.

  19. A Case of Vertical Transmission of Chagas Disease Contracted via Blood Transfusion in Canada

    Directory of Open Access Journals (Sweden)

    Margaret A Fearon

    2013-01-01

    Full Text Available Chagas disease is caused by the protozoan parasite Trypanosoma cruzi and is endemic in many countries in Latin America, where infected bugs of the Triatominea subfamily carry the parasite in the gut and transmit it to humans through fecal contamination of a bite. However, vertical transmission and transmission through blood transfusion and organ transplantation is well documented. Increasing immigration from endemic countries to North America has prompted blood operators, including Canadian Blood Services and Hema Quebec, to initiate blood donor testing for Chagas antibody. In the present report, an unusual case of vertical transmission from a mother, most likely infected through blood transfusion, and detected as part of a concurrent seroprevalence study in blood donors is described.

  20. Vertical and horizontal transmission of tilapia larvae encephalitis virus: the bad and the ugly.

    Science.gov (United States)

    Sinyakov, Michael S; Belotsky, Sandro; Shlapobersky, Mark; Avtalion, Ramy R

    2011-02-01

    Impairment of innate immunity in tilapia larvae after vertical and horizontal infection with the newly characterized tilapia larvae encephalitis virus (TLEV) was accessed by evaluation of cell-mediated reactive oxygen species (ROS) production in affected fish with the use of horseradish peroxidase-amplified luminol-dependent chemiluminescence assay. The priming in-vivo infection with TLEV resulted in downregulation of ROS response in both vertically- and horizontally-infected fish; this suppression was further exacerbated by specific in-vitro booster infection with the same virus. Application of Ca ionophore and phorbol myristate acetate as alternative nonspecific boosters enabled restoration of ROS release in vertically-infected but not in horizontally-infected larvae. The results indicate severe TLEV-imposed phagocyte dysfunction in affected larvae. The difference in restoration potential of ROS production after vertical and horizontal virus transmission is interpreted in the frame of principal distinctions between the two modes. PMID:21131016

  1. Economic evaluation of reliability-centred maintenance (RCM): an electricity transmission industry perspective

    International Nuclear Information System (INIS)

    Traditional approaches to appraising the introduction of reliability centred maintenance (RCM) are shown to exhibit severe limitations. In particular, the economic implications surrounding its adoption are repeatedly mis-stated, with the consequence that organisations may be investing in unprofitable RCM ventures. Previously quoted benefits are examined and, contrary to established opinion, it is shown that these 'generalised' statements, once redeemed, are able to be quantified. The paper then proceeds to describe a financial methodology, developed by NGC and UMIST, by which the introduction of RCM can be evaluated. Moreover, it shows that, by regarding RCM as an investment decision, rather than an 'act of faith', the economic viability of a potential application can be determined before vital resources are committed. Finally, it is demonstrated that when the methodology is applied within the context of the electricity transmission industry, the economic case underlying the adoption of RCM can be realistically appraised. (author)

  2. Conhecimento dos obstetras sobre a transmissão vertical da hepatite B Knowledge of obstetricians about the vertical transmission of hepatitis B virus

    Directory of Open Access Journals (Sweden)

    Joseni Santos da Conceição

    2009-03-01

    Full Text Available CONTEXTO: A transmissão vertical é responsável por 35% a 40% dos novos casos de hepatite B no mundo e a infecção precoce pelo vírus da hepatite B aumenta o risco de evolução para a hepatite crônica, cirrose e carcinoma hepatocelular. OBJETIVO: Determinar o conhecimento dos obstetras sobre as práticas para o diagnóstico da infecção pelo vírus da hepatite B em gestantes e as condutas para a prevenção desta infecção em recém-nascidos de mães infectadas. MÉTODOS: Foram sorteados aleatoriamente profissionais de saúde cadastrados na Sociedade de Obstetrícia e Ginecologia da Bahia, que foram convidados a responder um questionário anônimo com informações sobre sua formação acadêmica, o local de trabalho, o contato com estudantes e as suas práticas profissionais em relação ao vírus da hepatite B. Adotou-se como critério de exclusão o não exercício atual da obstetrícia e a não residência na Bahia. A análise dos dados foi feita através do programa estatístico Epiinfo e para análise das correlações foi adotado intervalo de confiança de 95%. RESULTADOS: Foram entrevistados 301 obstetras, dos quais 90,3% reconheciam a transmissibilidade vertical do vírus da hepatite B e 81,7% solicitavam algum exame para detecção de hepatite B durante o pré-natal de suas pacientes. Sessenta e seis por cento dos médicos entrevistados referiram o AgHBs como o marcador sorológico mais adequado para avaliar a presença de infecção pelo VHB. Apenas 13,0% destes profissionais indicavam de modo sistemático a vacina contra a hepatite B e a administração de imunoglobulina nas primeiras 12 horas de vida do recém-nascido de mães infectadas. O número de respostas corretas quanto à transmissibilidade vertical do VHB, ao marcador sorológico mais adequado e à conduta para o recém-nascido de mãe infectada foi maior entre os obstetras que possuíam o Título de Especialista em Ginecologia e Obstetrícia que entre os demais

  3. Larval Temperature-Food Effects on Adult Mosquito Infection and Vertical Transmission of Dengue-1 Virus.

    Science.gov (United States)

    Buckner, Eva A; Alto, Barry W; Lounibos, L Philip

    2016-01-01

    Temperature-food interactions in the larval environment can affect life history and population growth of container mosquitoes Aedes aegypti (L.) and Aedes albopictus Skuse, the primary vectors of chikungunya and dengue viruses. We used Ae. aegypti, Ae. albopictus, and dengue-1 virus (DENV-1) from Florida to investigate whether larval rearing temperature can alter the effects of larval food levels on Ae. aegypti and Ae. albopictus life history and DENV-1 infection and vertical transmission. Although we found no effect of larval treatments on survivorship to adulthood, DENV-1 titer, or DENV-1 vertical transmission, rates of vertical transmission up to 16-24% were observed in Ae. albopictus and Ae. aegypti, which may contribute to maintenance of this virus in nature. Larval treatments had no effect on number of progeny and DENV-1 infection in Ae. aegypti, but the interaction between temperature and food affected number of progeny and DENV-1 infection of the female Ae. albopictus parent. The cooler temperature (24°C) yielded the most progeny and this effect was accentuated by high food relative to the other conditions. Low and high food led to the highest (∼90%) and lowest (∼65%) parental infection at the cooler temperature, respectively, whereas intermediate infection rates (∼75-80%) were observed for all food conditions at the elevated temperature. These results suggest that temperature and food availability have minimal influence on rate of vertical transmission and a stronger influence on adults of Ae. albopictus than of Ae. aegypti, which could have consequences for dengue virus epidemiology. PMID:26489999

  4. Vertical Transmission of a Phylogenetically Complex Microbial Consortium in the Viviparous Sponge Ircinia felix▿

    OpenAIRE

    Schmitt, Susanne; Weisz, Jeremy B; Lindquist, Niels; Hentschel, Ute

    2007-01-01

    Many marine demosponges contain large amounts of phylogenetically complex yet highly sponge-specific microbial consortia within the mesohyl matrix, but little is known about how these microorganisms are acquired by their hosts. Settlement experiments were performed with the viviparous Caribbean demosponge Ircinia felix to investigate the role of larvae in the vertical transmission of the sponge-associated microbial community. Inspections by electron microscopy revealed large amounts of morpho...

  5. Two profitless delays for an SEIRS epidemic disease model with vertical transmission and pulse vaccination

    International Nuclear Information System (INIS)

    Since the investigation of impulsive delay differential equations is beginning, the literature on delay epidemic models with pulse vaccination is not extensive. In this paper, we propose a new SEIRS epidemic disease model with two profitless delays and vertical transmission, and analyze the dynamics behaviors of the model under pulse vaccination. Using the discrete dynamical system determined by the stroboscopic map, we obtain a 'infection-free' periodic solution, further, show that the 'infection-free' periodic solution is globally attractive when some parameters of the model are under appropriate conditions. Using a new modeling method, we obtain sufficient condition for the permanence of the epidemic model with pulse vaccination. We show that time delays, pulse vaccination and vertical transmission can bring different effects on the dynamics behaviors of the model by numerical analysis. Our results also show the delays are 'profitless'. In this paper, the main feature is to introduce two discrete time delays, vertical transmission and impulse into SEIRS epidemic model and to give pulse vaccination strategies.

  6. The Evolution of Musical Diversity: The Key Role of Vertical Transmission

    Science.gov (United States)

    Le Bomin, Sylvie; Lecointre, Guillaume; Heyer, Evelyne

    2016-01-01

    Music, like languages, is one of the key components of our culture, yet musical evolution is still poorly known. Numerous studies using computational methods derived from evolutionary biology have been successfully applied to varied subset of linguistic data. One of the major drawback regarding musical studies is the lack of suitable coded musical data that can be analysed using such evolutionary tools. Here we present for the first time an original set of musical data coded in a way that enables construction of trees classically used in evolutionary approaches. Using phylogenetic methods, we test two competing theories on musical evolution: vertical versus horizontal transmission. We show that, contrary to what is currently believed, vertical transmission plays a key role in shaping musical diversity. The signal of vertical transmission is particularly strong for intrinsic musical characters such as metrics, rhythm, and melody. Our findings reveal some of the evolutionary mechanisms at play for explaining musical diversity and open a new field of investigation in musical evolution. PMID:27027305

  7. The importance of vertical transmission of Neospora sp. in naturally infected horses.

    Science.gov (United States)

    Antonello, Ana Maria; Pivoto, Felipe Lamberti; Camillo, Giovana; Braunig, Patricia; Sangioni, Luis Antonio; Pompermayer, Endrigo; Vogel, Fernanda Silveira Flores

    2012-07-01

    Neospora spp. is a intracellular protozoan phylogenetically closely related to Toxoplasma gondii and Sarcocystis neurona, and it can infect horses leading to the development of reproductive or neurological diseases. We determined the presence of antibodies to Neospora sp. in mares at their parturition time and determine the frequency of vertical transmission in healthy foals to verify the importance of transplacental transmission. The samples were analyzed by indirect immunofluorescence antibody test, showing that seroprevalence in mares is higher than in foals and seropositive mares are likely to transmit the neosporosis to their offspring. This shows that endogenous challenge occurs in horses, and it suggests that this protozoan can be disseminated by means of transplacental transmission in horse species. PMID:22436425

  8. Evaluation of procalcitonin for diagnosis of neonatal sepsis of vertical transmission

    Science.gov (United States)

    López Sastre, José B; Solís, David Pérez; Serradilla, Vicente Roqués; Colomer, Belén Fernández; Cotallo, Gil D Coto

    2007-01-01

    Background The results of recent studies suggest the usefulness of PCT for early diagnosis of neonatal sepsis, with varying results. The aim of this prospective multicenter study was to determine the behavior of serum PCT concentrations in both uninfected and infected neonates, and to assess the value of this marker for diagnosis of neonatal sepsis of vertical transmission. Methods PCT was measured in 827 blood samples collected prospectively from 317 neonates admitted to 13 acute-care teaching hospitals in Spain over one year. Serum PCT concentrations were determined by a specific immunoluminometric assay. The diagnostic efficacy of PCT at birth and within 12–24 h and 36–48 h of life was evaluated calculating the sensitivity, specificity, and likelihood ratio of positive and negative results. Results 169 asymptomatic newborns and 148 symptomatic newborns (confirmed vertical sepsis: 31, vertical clinical sepsis: 38, non-infectious diseases: 79) were studied. In asymptomatic neonates, PCT values at 12–24 h were significantly higher than at birth and at 36–48 h of life. Resuscitation at birth and chorioamnionitis were independently associated to PCT values. Neonates with confirmed vertical sepsis showed significantly higher PCT values than those with clinical sepsis. PCT thresholds for the diagnosis of sepsis were 0.55 ng/mL at birth (sensitivity 75.4%, specificity 72.3%); 4.7 ng/mL within 12–24 h of life (sensitivity 73.8%, specificity 80.8%); and 1.7 ng/mL within 36–48 h of life (sensitivity 77.6%, specificity 79.2%). Conclusion Serum PCT was moderately useful for the detection of sepsis of vertical transmission, and its reliability as a maker of bacterial infection requires specific cutoff values for each evaluation point over the first 48 h of life. PMID:17324267

  9. Cellular and molecular remodelling of a host cell for vertical transmission of bacterial symbionts

    Science.gov (United States)

    Luan, Jun-Bo; Shan, Hong-Wei; Isermann, Philipp; Huang, Jia-Hsin; Lammerding, Jan; Liu, Shu-Sheng; Douglas, Angela E.

    2016-01-01

    Various insects require intracellular bacteria that are restricted to specialized cells (bacteriocytes) and are transmitted vertically via the female ovary, but the transmission mechanisms are obscure. We hypothesized that, in the whitefly Bemisia tabaci, where intact bacteriocytes (and not isolated bacteria) are transferred to oocytes, the transmission mechanism would be evident as cellular and molecular differences between the nymph (pre-adult) and adult bacteriocytes. We demonstrate dramatic remodelling of bacteriocytes at the developmental transition from nymph to adulthood. This transition involves the loss of cell–cell adhesion, high division rates to constant cell size and onset of cell mobility, enabling the bacteriocytes to crawl to the ovaries. These changes are accompanied by cytoskeleton reorganization and changes in gene expression: genes functioning in cell–cell adhesion display reduced expression and genes involved in cell division, cell motility and endocytosis/exocytosis have elevated expression in adult bacteriocytes, relative to nymph bacteriocytes. This study demonstrates, for the first time, how developmentally orchestrated remodelling of gene expression and correlated changes in cell behaviour underpin the capacity of bacteriocytes to mediate the vertical transmission and persistence of the symbiotic bacteria on which the insect host depends. PMID:27358364

  10. Transmission of vertical stress in a real soil profile. Part I

    DEFF Research Database (Denmark)

    Lamandé, Mathieu; Schjønning, Per

    2011-01-01

    Transmission of stresses in the soil profile is one crucial ingredient of the ‘chain of cause and effect’ leading to either persistent deformation or elastic deformation. This study is the first of a series of three, where effects of contact stress and soil conditions on the stress distribution in...... the soil profile were evaluated. Measurements of vertical stresses were performed in an undisturbed Stagnic luvisol in three dimensions during one pass of one wheel (in depth, across and along the driving direction). In the present study, we tested the effect of loosening the topsoil by 20 cm...... ploughing on the stress distribution in the soil profile. The reference soil had not been ploughed or otherwise tilled for 18 months. The distribution of vertical stress near the tyre–soil interface was fitted by a model combining a power function and an exponential function for the stresses, respectively...

  11. Vertical transmission of Zika virus targeting the radial glial cells affects cortex development of offspring mice.

    Science.gov (United States)

    Wu, Kong-Yan; Zuo, Guo-Long; Li, Xiao-Feng; Ye, Qing; Deng, Yong-Qiang; Huang, Xing-Yao; Cao, Wu-Chun; Qin, Cheng-Feng; Luo, Zhen-Ge

    2016-06-01

    The recent Zika virus (ZIKV) epidemic in Latin America coincided with a marked increase in microcephaly in newborns. However, the causal link between maternal ZIKV infection and malformation of the fetal brain has not been firmly established. Here we show a vertical transmission of ZIKV in mice and a marked effect on fetal brain development. We found that intraperitoneal (i.p.) injection of a contemporary ZIKV strain in pregnant mice led to the infection of radial glia cells (RGs) of dorsal ventricular zone of the fetuses, the primary neural progenitors responsible for cortex development, and caused a marked reduction of these cortex founder cells in the fetuses. Interestingly, the infected fetal mice exhibited a reduced cavity of lateral ventricles and a discernable decrease in surface areas of the cortex. This study thus supports the conclusion that vertically transmitted ZIKV affects fetal brain development and provides a valuable animal model for the evaluation of potential therapeutic or preventative strategies. PMID:27174054

  12. Vertical transmission of Zika virus targeting the radial glial cells affects cortex development of offspring mice

    Science.gov (United States)

    Wu, Kong-Yan; Zuo, Guo-Long; Li, Xiao-Feng; Ye, Qing; Deng, Yong-Qiang; Huang, Xing-Yao; Cao, Wu-Chun; Qin, Cheng-Feng; Luo, Zhen-Ge

    2016-01-01

    The recent Zika virus (ZIKV) epidemic in Latin America coincided with a marked increase in microcephaly in newborns. However, the causal link between maternal ZIKV infection and malformation of the fetal brain has not been firmly established. Here we show a vertical transmission of ZIKV in mice and a marked effect on fetal brain development. We found that intraperitoneal (i.p.) injection of a contemporary ZIKV strain in pregnant mice led to the infection of radial glia cells (RGs) of dorsal ventricular zone of the fetuses, the primary neural progenitors responsible for cortex development, and caused a marked reduction of these cortex founder cells in the fetuses. Interestingly, the infected fetal mice exhibited a reduced cavity of lateral ventricles and a discernable decrease in surface areas of the cortex. This study thus supports the conclusion that vertically transmitted ZIKV affects fetal brain development and provides a valuable animal model for the evaluation of potential therapeutic or preventative strategies. PMID:27174054

  13. The importance of addressing gender inequality in efforts to end vertical transmission of HIV

    Directory of Open Access Journals (Sweden)

    Dean Peacock

    2012-07-01

    Full Text Available Issues: The recently launched “Global Plan towards the Elimination of New HIV Infections among Children by 2015 and Keeping their Mothers Alive” sets forth ambitious targets that will require more widespread implementation of comprehensive prevention of vertical HIV transmission (PMTCT programmes. As PMTCT policymakers and implementers work toward these new goals, increased attention must be paid to the role that gender inequality plays in limiting PMTCT programmatic progress. Description: A growing body of evidence suggests that gender inequality, including gender-based violence, is a key obstacle to better outcomes related to all four components of a comprehensive PMTCT programme. Gender inequality affects the ability of women and girls to protect themselves from HIV, prevent unintended pregnancies and access and continue to use HIV prevention, care and treatment services. Lessons Learned: In light of this evidence, global health donors and international bodies increasingly recognize that it is critical to address the gender disparities that put women and children at increased risk of HIV and impede their access to care. The current policy environment provides unprecedented opportunities for PMTCT implementers to integrate efforts to address gender inequality with efforts to expand access to clinical interventions for preventing vertical HIV transmission. Effective community- and facility-based strategies to transform harmful gender norms and mitigate the impacts of gender inequality on HIV-related outcomes are emerging. PMTCT programmes must embrace these strategies and expand beyond the traditional focus of delivering ARV prophylaxis to pregnant women living with HIV. Without greater implementation of comprehensive, gender transformative PMTCT programmes, elimination of vertical transmission of HIV will remain elusive.

  14. Vertical Price Transmission in Local Rice Markets in Cote d'Ivoire: Are Consumers Really Right?

    Directory of Open Access Journals (Sweden)

    Yaya KEHO

    2012-12-01

    Full Text Available This paper analyses vertical relationships between wholesale and retail prices in three local rice markets in Côte d’Ivoire. The aim of the paper is to ascertain whether the popular complaint of consumers about the asymmetric price transmission holds true. Our empirical analysis makes use of threshold cointegration and error correction models and monthly data for the period 1990-1999. We found that wholesale and retail prices are cointegrated and increases in wholesale prices are passed on to retail prices more quickly than decreases.

  15. Overview of Studies on Vertical Price Transmission of Agro-products

    Institute of Scientific and Technical Information of China (English)

    Yun; GAO

    2013-01-01

    Research on price transmission in vertically markets models the various price data, production index, consumer index and expectations index to proof market integration relations and estimate price transmission cycles, as well as to find out its function mechanism. Thanks to the development of market integration theory, research in this field explored well-rounded metric models. And the main research results are very closely to. To build up systematic models to input more variables based on demand and supply function, and remove the assumption of constant returns to scale of enterprises involving marketing and fully competitive market would be the development direction in this field. In this way, models draw close to the truth of economic operations.

  16. Micro-size antenna structure with vertical nanowires for wireless power transmission and communication.

    Science.gov (United States)

    Kang, Jong-Gu; Jeong, Yeri; Shin, Jeong Hee; Choi, Ji-Woong; Sohn, Jung Inn; Cha, Seung Nam; Jang, Jae Eun

    2014-11-01

    For biomedical implanted devices, a wireless power or a signal transmission is essential to protect an infection and to enhance durability. In this study, we present a magnetic induction technique for a power transmission without any wire connection between transmitter (Tx) and receiver (Rx) in a micro scale. Due to a micro size effect of a flat spiral coil, a magnetic inductance is not high. To enhance the magnetic inductance, a three dimensional magnetic core is added to an antenna structure, which is consisted of ZnO nano wires coated by a nickel (Ni) layer. ZnO nano wires easily supply a large effective surface area with a vertical structural effect to the magnetic core structure, which induces a higher magnetic inductance with a ferro-magnetic material Ni. The magnetic induction antenna with the magnetic core shows a high inductance value, a low reflection power and a strong power transmission. The power transmission efficiencies are tested under the air and the water medium are almost the same values, so that the magnetic induction technique is quite proper to body implanted systems. PMID:25958501

  17. Vertical transmission and fetal damage in animal models of congenital toxoplasmosis: A systematic review.

    Science.gov (United States)

    Vargas-Villavicencio, José Antonio; Besné-Mérida, Alejandro; Correa, Dolores

    2016-06-15

    In humans, the probability of congenital infection and fetal damage due to Toxoplasma gondii is dependent on the gestation period at which primary infection occurs. Many animal models have been used for vaccine, drug testing, or studies on host or parasite factors that affect transmission or fetal pathology, but few works have directly tested fetal infection and damage rates along gestation. So, the purpose of this work was to perform a systematic review of the literature to determine if there is a model which reflects these changes as they occur in humans. We looked for papers appearing between 1970 and 2014 in major databases like Medline and Scopus, as well as gray literature. From almost 11,000 citations obtained, only 49 papers fulfilled the criteria of having data of all independent variables and at least one dependent datum for control (untreated) groups. Some interesting findings could be extracted. For example, pigs seem resistant and sheep susceptible to congenital infection. Also, oocysts cause more congenitally infected offspring than tissue cysts, bradyzoites or tachyzoites. In spite of these interesting findings, very few results on vertical transmission or fetal damage rates were similar to those described for humans and only for one of the gestation thirds, not all. Moreover, in most designs tissue cysts - with unknown number of bradyzoites - were used, so actual dose could not be established. The meta-analysis could not be performed, mainly because of great heterogeneity in experimental conditions. Nevertheless, results gathered suggest that a model could be designed to represent the increase in vertical transmission and decrease in fetal damage found in humans under natural conditions. PMID:27198800

  18. Is the vertical transmission of Neotyphodium lolii in perennial ryegrass the only possible way to the spread of endophytes?

    Directory of Open Access Journals (Sweden)

    Barbara Wiewióra

    Full Text Available Endophytic fungi live their whole life within host tissues usually without any visible symptoms. Their vertical transmission (seed-plant-seed has been well described and documented. However, horizontal transmission (plant-plant needs more clarification. The aim of this study was to assess the extent to which endophytes move vertically in ecotypes of perennial ryegrass and whether there is evidence for the horizontal transmission of endophytes. Ecotypes from grasslands in Poland were collected in the form of living plants and used for vertical transmission analysis. Plants, the seed collected from these plants and plants grown from this collected seed were tested for endophytic infection. Provided that all produced seeds were viable and able to germinate and produce seedlings, the vertical transmission of Neotyphodium endophytes in perennial ryegrass ecotypes was nearly complete. For the horizontal transmission experiment, endophyte-hosting plants (E+ and endophyte-free plants (E- of four cultivars were planted in the field in close proximity on small plots that were frequently mown. These studies revealed that after 7 months of growth next to E+ plants, the characteristic Neotyphodium spp. mycelia were found in E- plants, which was especially true for plants growing in close proximity to the infected plants. The occurrence of horizontal transmission of endophytes has not been previously demonstrated.

  19. Narrow bottlenecks affect Pea seedborne mosaic virus populations during vertical seed transmission but not during leaf colonization.

    Directory of Open Access Journals (Sweden)

    Frédéric Fabre

    2014-01-01

    Full Text Available The effective size of populations (Ne determines whether selection or genetic drift is the predominant force shaping their genetic structure and evolution. Populations having high Ne adapt faster, as selection acts more intensely, than populations having low Ne, where random effects of genetic drift dominate. Estimating Ne for various steps of plant virus life cycle has been the focus of several studies in the last decade, but no estimates are available for the vertical transmission of plant viruses, although virus seed transmission is economically significant in at least 18% of plant viruses in at least one plant species. Here we study the co-dynamics of two variants of Pea seedborne mosaic virus (PSbMV colonizing leaves of pea plants (Pisum sativum L. during the whole flowering period, and their subsequent transmission to plant progeny through seeds. Whereas classical estimators of Ne could be used for leaf infection at the systemic level, as virus variants were equally competitive, dedicated stochastic models were needed to estimate Ne during vertical transmission. Very little genetic drift was observed during the infection of apical leaves, with Ne values ranging from 59 to 216. In contrast, a very drastic genetic drift was observed during vertical transmission, with an average number of infectious virus particles contributing to the infection of a seedling from an infected mother plant close to one. A simple model of vertical transmission, assuming a cumulative action of virus infectious particles and a virus density threshold required for vertical transmission to occur fitted the experimental data very satisfactorily. This study reveals that vertically-transmitted viruses endure bottlenecks as narrow as those imposed by horizontal transmission. These bottlenecks are likely to slow down virus adaptation and could decrease virus fitness and virulence.

  20. Genotyping of Giardia duodenalis isolates in asymptomatic children attending daycare centre: evidence of high risk for anthroponotic transmission.

    Science.gov (United States)

    Oliveira-Arbex, A P; David, E B; Oliveira-Sequeira, T C G; Bittencourt, G N; Guimarães, S

    2016-05-01

    Giardia duodenalis is a common intestinal parasite infecting children attending daycare centres. This study aimed to verify Giardia occurrence and the genotypes of isolates infecting children aged 0-6 years and workers at a daycare centre in the state of São Paulo, Brazil. The families of children who tested positive for Giardia, were asked to provide stool samples from household members and their dogs. Samples (123 children, 14 centre employees, 44 household members, 19 children after treatment, and 20 dogs) were examined for intestinal parasites using concentration methods. DNA extracted from all samples was submitted for polymerase chain reaction (PCR) testing and the amplicons generated were used for multilocus sequence typing of beta-giardin (bg), triose phosphate isomerase (tpi) and glutamate dehydrogenase (gdh) genes. Giardia was detected in 15·9% and 28·6% of the 220 samples by microscopy and PCR, respectively. Analysis of sequences retrieved from 29 isolates revealed both assemblages A (31%) and B (69%). Sub-assemblages AII, BIII and BIV were identified and the alignment of the bg, gdh and tpi sequences revealed the presence of some single nucleotide polymorphisms, especially in assemblage B sequences. The higher predominance of assemblage B and the identification of the AII type support the view that anthroponotic transmission appears to be an important route of transmission in environments that concentrate children at an age when poor hygiene practices make them more vulnerable to such infection. PMID:26593069

  1. A transmission line method for evaluation of vertical InAs nanowire contacts

    International Nuclear Information System (INIS)

    In this paper, we present a method for metal contact characterization to vertical semiconductor nanowires using the transmission line method (TLM) on a cylindrical geometry. InAs nanowire resistors are fabricated on Si substrates using a hydrogen silsesquioxane (HSQ) spacer between the bottom and top contact. The thickness of the HSQ is defined by the dose of an electron beam lithography step, and by varying the separation thickness for a group of resistors, a TLM series is fabricated. Using this method, the resistivity and specific contact resistance are determined for InAs nanowires with different doping and annealing conditions. The contacts are shown to improve with annealing at temperatures up to 300 °C for 1 min, with specific contact resistance values reaching down to below 1 Ω µm2

  2. Measurement of the wetting profile in concrete samples with vertical water by gamma radiation transmission method

    International Nuclear Information System (INIS)

    Samples of concrete for popular habitation (0,1x0,03x0,1 m) and cellular concrete (0,1x0,05x0,1 m) were submitted to water vertical ascending infiltration. The moisture content spatial and temporal evolution of each sample it was monitored in three halfway positions in a same horizontal line, applying the gamma rays transmission method. The data were taken with a 137Cs (3,7x1010 Bq, 0662 MeV) source, NaI (Tl) of 2x2' detector coupled to between wetting profiles and concrete strength. The cellular concrete showed a wetting profile compatible to its greater porosity. (author)

  3. Moisture profile measurements of concrete samples in vertical water flow by gamma ray transmission method

    International Nuclear Information System (INIS)

    Samples of concrete for popular habitation (0.1x0.03x0.1 m) and cellular concrete (0.1x0.05x0.1 m) were submitted to water vertical ascending infiltration. The moisture content spatial and temporal evolution of each sample it was monitored in three halfway positions in a same horizontal line, applying the gamma rays transmission method. The data were taken with a 137Cs (3.7x1010 Bq, 0662 MeV) source, NaI (Tl) of 2x2'' detector coupled to gamma ray spectrometry standard electronic with multichannel analyzer and a micrometric table. For the popular habitation concrete, there was a clear correlation between wetting profiles and concrete strength. The cellular concrete showed a wetting profile compatible to its greater porosity. (author)

  4. Study on HBV Vertical Transmission via the in vitro Fertilization(IVF)Technique

    Institute of Scientific and Technical Information of China (English)

    Jing-ning YANG; Qing-bin LUO; Chang-jun ZHANG; Hua WANG

    2009-01-01

    Objective To study the hepatitis B virus(HB V)vertical transmission via infected spermatozoa.Methods Eighteen male patients with HBV infection who underwent in vitro fertilization (IVF)were studied,5 HBV negative patients were selected as the control.Fluorescence in situ hybridization(FISH)analysis using the partial-length HBV DNA as the hybridization probe was performed to explore the existence of HBV DNA in the sperm and in the host embryonic genome.Results FISH showed that 5 of 18 patients' sperm presented positive signals and 2 of 18 embryos presented positive signals,while no positive signals were found in control group.Conclusion The HBV DNA was found in human sperm and embryos of HBV patients.These results provide direct evidence that HBV DNA could transmit to foetus via human infected spermatozoa.

  5. AIDS em gestantes: possibilidade de reduzir a transmissão vertical

    Directory of Open Access Journals (Sweden)

    Fernanda Scherer Wiethäuper

    2003-06-01

    Full Text Available Neste estudo, buscamos investigar o conhecimento que gestantes possuem sobre a transmissão vertical, o comprometimento do feto e o significado do resultado soropositivo que a identifica como infectada pelo HIV. A pesquisa exploratória, de natureza qualitativa, foi desenvolvida em Unidades Sanitárias de São Leopoldo/RS. A análise permitiu captar a percepção de 63 gestantes entre 16 e 40 anos sobre os motivos e os significados para realização do teste, os conhecimentos e vivências do cotidiano e as perspectivas e cuidados com o bebê. Os resultados trazem um alerta aos profissionais que atuam no pré-natal, visto que necessitam atender uma complexidade de situações que emergem quando se vincula gestação e AIDS.

  6. Moisture profile measurements of concrete samples in vertical water flow by gamma ray transmission method

    Science.gov (United States)

    da Rocha, M. C.; da Silva, L. M.; Appoloni, C. R.; Portezan Filho, O.; Lopes, F.; Melquíades, F. L.; dos Santos, E. A.; dos Santos, A. O.; Moreira, A. C.; Pötker, W. E.; de Almeida, E.; Tannous, C. Q.; Kuramoto, R.; Cavalcante, F. H. de M.; Barbieri, P. F.; Caleffi, A. F.; Carbonari, B. T.; Carbonari, G.

    2001-06-01

    Samples of concrete for popular habitation (0.1×0.03×0.1 m) and cellular concrete (0.1×0.05×0.1 m) were submitted to water vertical ascending infiltration. The moisture content spatial and temporal evolution of each sample it was monitored in three halfway positions in a same horizontal line, applying the gamma rays transmission method. The data were taken with a 137Cs (3.7×1010 Bq, 0662 MeV) source, Nal (Tl) of 2×2″ detector coupled to gamma ray spectrometry standard electronic with multichannel analyzer and a micrometric table. For the popular habitation concrete, there was a clear correlation between wetting profiles and concrete strength. The cellular concrete showed a wetting profile compatible to its greater porosity.

  7. Airborne lidar measurements of smoke plume distribution, vertical transmission, and particle size

    International Nuclear Information System (INIS)

    Observations were made of a dense smoke plume downwind from a forest using the ALPHA-1 two-wavelength downward-looking airborne lidar system. Facsimile displays derived from lidar signatures depict plume dimensions, boundary layer height, and underlying terrain elevation. Surface returns are interpreted in terms of vertical transmissions as function of cross-plume distance. Results show significantly greater plume attenuation at 0.53-μm wavelength than at 1.06-μm, indicating approx.0.1-μm mean particle diameters of the presence of gaseous constituents that absorb the visible radiation. These results demonstrate the potential of multiple-wavelength airborne lidar for quantitative analysis of atmospheric particulate and gaseous constituents

  8. A transmission line method for evaluation of vertical InAs nanowire contacts

    Energy Technology Data Exchange (ETDEWEB)

    Berg, M., E-mail: martin.berg@eit.lth.se; Svensson, J., E-mail: johannes.svensson@eit.lth.se; Lind, E., E-mail: erik.lind@eit.lth.se; Wernersson, L.-E., E-mail: lars-erik.wernersson@eit.lth.se [Department of Electrical and Information Technology, Lund University, Box 118, SE-221 00 Lund (Sweden)

    2015-12-07

    In this paper, we present a method for metal contact characterization to vertical semiconductor nanowires using the transmission line method (TLM) on a cylindrical geometry. InAs nanowire resistors are fabricated on Si substrates using a hydrogen silsesquioxane (HSQ) spacer between the bottom and top contact. The thickness of the HSQ is defined by the dose of an electron beam lithography step, and by varying the separation thickness for a group of resistors, a TLM series is fabricated. Using this method, the resistivity and specific contact resistance are determined for InAs nanowires with different doping and annealing conditions. The contacts are shown to improve with annealing at temperatures up to 300 °C for 1 min, with specific contact resistance values reaching down to below 1 Ω µm{sup 2}.

  9. Evidence of vertical transmission and tissue tropism of Streptococcosis from naturally infected red tilapia (Oreochromis spp.

    Directory of Open Access Journals (Sweden)

    Padmaja Jayaprasad Pradeep

    2016-05-01

    Full Text Available Streptococcosis is a highly problematic disease in the aquaculture of freshwater fishes, especially for tilapia. The possibility of vertical transmission of streptococcosis and the pattern of tissue tropism of this pathogen in various organs was examined in red tilapia (Oreochromis sp.. Healthy broodstock without any clinical signs of Streptococcus spp. were selected from a farm earlier reported to have the disease and a total of 10 pairs were forced spawned to provide samples of gametes and progeny for pathogen testing. A colorimetric LAMP assay was used to confirm whether the bacterial pathogens Streptococcus. agalactiae and Streptococcus. iniae was present in samples of milt, unfertilized eggs, fertilized eggs, and offspring at various stages of development, as well as internal organs of broodstock (reproductive organs, gill, liver, spleen, kidney and brain as well as samples of water from culture systems. The majority of samples of milt (9/10 and unfertilized eggs (7/10 collected from the broodstock were infected with S. iniae at the time of spawning and was transmitted to all of their offspring. Nevertheless, when the same samples of gametes were analyzed for S. agalactiae, they were all found to be negative but the pathogen was found to be present in some 10-day-old larval offspring (4/10. However, when the pathogenic presence was analyzed from the reproductive organs of the parents, both S. agalactiae (11/20 and S. iniae (18/20 bacterium were common. Although, all broodstock were asymptomatic, almost all broodstock harboured the bacteria in many organs. Confirmation of vertical transmission of streptococcosis in tilapia means that intergenerational break cannot be used as a reliable and simple means of reducing or eliminating the prevalence of these difficult pathogens in aquaculture stock.

  10. Transmissão vertical do HIV em população atendida no serviço de referência Vertical transmission of HIV in the population treated at a reference center

    Directory of Open Access Journals (Sweden)

    Sueli Teresinha Cruz Rodrigues

    2013-01-01

    Full Text Available OBJETIVO: Identificar a taxa de transmissão vertical do HIV e avaliar os fatores envolvidos em partes materna e fetal. MÉTODOS: Estudo transversal realizado no Serviço de Atendimento Especializado. Foram investigados 102 prontuários de mulheres com HIV que deram à luz a recém-nascidos vivos. RESULTADOS: A prevalência de 6,6% de transmissão vertical. Entre as crianças infectadas: 40,0% de mães sem pré-natal e 75% sem a profilaxia com anti-retrovirais durante o pré-natal, 50,0% sem profilaxia com AZT com oral e amamentado. Entre as crianças não infectadas: 91,5% iniciaram a profilaxia com AZT oral ao nascimento e 84,1% das mães receberam ARV. CONCLUSÃO: A ocorrência de transmissão vertical do HIV no serviço de referência correspondeu a 6,6%, o que indica uma alta prevalência.OBJECTIVE: To identify the rate of vertical transmission of HIV and assess the factors involved in maternal and fetal share. METHODS: Cross-sectional study conducted in the Specialized Care Service. We investigated 102 clinical records of HIV positive women who had given birth to live newborns. The primary variable was the occurrence of vertical transmission of HIV and the secondary variables were the factors associated with vertical transmission of HIV. RESULTS: Prevalence of 6.6% of vertical transmission. Among the infected children: 40.0% of mothers with out prenatal care and 75% without prophylaxis with antiretroviral drugs during the prenatal, 50.0% without AZT prophylaxis with oral and breast-fed. Among the uninfected children: 91.5% were started on prophylaxis with oral AZT at birth and 84.1% of mothers received ARV delivery. CONCLUSION: The occurrence of vertical transmission of HIV in the reference service corresponded to 6.6%, indicating a high prevalence.

  11. Safety of single-dose nevirapine for prevention of vertical transmission of human immunodeficiency virus infection

    Directory of Open Access Journals (Sweden)

    Mangala Bhaskar Murthy

    2011-01-01

    Full Text Available Introduction : Nevirapine administered as a single dose each to the mother and child within 72 h after birth is used to prevent vertical transmission of human immunodeficiency virus (HIV under the prevention of parent to child transmission of HIV program (PPTCT. The efficacy of nevirapine in this regard has been proved beyond doubt, but there are unresolved questions about its safety. Hence, the primary objective of this study was to evaluate the safety of this regime. Materials and Methods : HIV-positive pregnant women who consented to participate in the study received a single oral dose of 200 mg nevirapine at the onset of labor followed by administration of 2 mg/kg of nevirapine syrup to the newborn within 72 h of birth. Both mother and child were followed up for 1 week postpartum to note the occurrence of any adverse reactions. Results : The mother and child followed up for 1 week postpartum did not show any serious adverse reactions in the present study. Mothers reported adverse reactions like nausea, vomiting, and headache which were self-limiting and did not require any intervention. Conclusion : The present study substantiates the safety of nevirapine.

  12. Evidence for horizontal and vertical transmission in Campylobacter passage from hen to her progeny.

    Science.gov (United States)

    Cox, N A; Richardson, L J; Maurer, J J; Berrang, M E; Fedorka-Cray, P J; Buhr, R J; Byrd, J A; Lee, M D; Hofacre, C L; O'Kane, P M; Lammerding, A M; Clark, A G; Thayer, S G; Doyle, M P

    2012-10-01

    Campylobacter is an important human pathogen, and consumption of undercooked poultry has been linked to significant human illnesses. To reduce human illness, intervention strategies targeting Campylobacter reduction in poultry are in development. For more than a decade, there has been an ongoing national and international controversy about whether Campylobacter can pass from one generation of poultry to the next via the fertile egg. We recognize that there are numerous sources of Campylobacter entry into flocks of commercial poultry (including egg transmission), yet the environment is often cited as the only source. There has been an abundance of published research globally that refutes this contention, and this article lists and discusses many of them, along with other studies that support environment as the sole or primary source. One must remember that egg passage can mean more than vertical, transovarian transmission. Fecal bacteria, including Campylobacter, can contaminate the shell, shell membranes, and albumen of freshly laid fertile eggs. This contamination is drawn through the shell by temperature differential, aided by the presence of moisture (the "sweating" of the egg); then, when the chick emerges from the egg, it can ingest bacteria such as Campylobacter, become colonized, and spread this contamination to flock mates in the grow house. Improvements in cultural laboratory methods continue to advance our knowledge of the ecology of Campylobacter, and in the not-so-distant future, egg passage will not be a subject continuously debated but will be embraced, thus allowing the development and implementation of more effective intervention strategies. PMID:23043845

  13. Prevention of mother-to-child HIV-1 transmission in Burkina Faso: evaluation of vertical transmission by PCR, molecular characterization of subtypes and determination of antiretroviral drugs resistance

    Science.gov (United States)

    Sagna, Tani; Bisseye, Cyrille; Compaore, Tegewende R.; Kagone, Therese S.; Djigma, Florencia W.; Ouermi, Djeneba; Pirkle, Catherine M.; Zeba, Moctar T. A.; Bazie, Valerie J. T.; Douamba, Zoenabo; Moret, Remy; Pietra, Virginio; Koama, Adjirita; Gnoula, Charlemagne; Sia, Joseph D.; Nikiema, Jean-Baptiste; Simpore, Jacques

    2015-01-01

    Background Vertical human immunodeficiency virus (HIV) transmission is a public health problem in Burkina Faso. The main objective of this study on the prevention of mother-to-child HIV-1 transmission was to determine the residual risk of HIV transmission in infants born to mothers receiving highly active antiretroviral therapy (HAART). Moreover, we detect HIV antiretroviral (ARV) drug resistance among mother–infant pairs and identify subtypes and circulating recombinant forms (CRF) in Burkina Faso. Design In this study, 3,215 samples of pregnant women were analyzed for HIV using rapid tests. Vertical transmission was estimated by polymerase chain reaction in 6-month-old infants born to women who tested HIV positive. HIV-1 resistance to ARV, subtypes, and CRFs was determined through ViroSeq kit using the ABI PRISM 3,130 sequencer. Results In this study, 12.26% (394/3,215) of the pregnant women were diagnosed HIV positive. There was 0.52% (2/388) overall vertical transmission of HIV, with rates of 1.75% (2/114) among mothers under prophylaxis and 0.00% (0/274) for those under HAART. Genetic mutations were also isolated that induce resistance to ARV such as M184V, Y115F, K103N, Y181C, V179E, and G190A. There were subtypes and CRF of HIV-1 present, the most common being: CRF06_CPX (58.8%), CRF02_AG (35.3%), and subtype G (5.9%). Conclusions ARV drugs reduce the residual rate of HIV vertical transmission. However, the virus has developed resistance to ARV, which could limit future therapeutic options when treatment is needed. Resistance to ARV therefore requires a permanent interaction between researchers, physicians, and pharmacists, to strengthen the network of monitoring and surveillance of drug resistance in Burkina Faso. PMID:25630709

  14. Prevention of mother-to-child HIV-1 transmission in Burkina Faso: evaluation of vertical transmission by PCR, molecular characterization of subtypes and determination of antiretroviral drugs resistance

    Directory of Open Access Journals (Sweden)

    Tani Sagna

    2015-01-01

    Full Text Available Background: Vertical human immunodeficiency virus (HIV transmission is a public health problem in Burkina Faso. The main objective of this study on the prevention of mother-to-child HIV-1 transmission was to determine the residual risk of HIV transmission in infants born to mothers receiving highly active antiretroviral therapy (HAART. Moreover, we detect HIV antiretroviral (ARV drug resistance among mother–infant pairs and identify subtypes and circulating recombinant forms (CRF in Burkina Faso. Design: In this study, 3,215 samples of pregnant women were analyzed for HIV using rapid tests. Vertical transmission was estimated by polymerase chain reaction in 6-month-old infants born to women who tested HIV positive. HIV-1 resistance to ARV, subtypes, and CRFs was determined through ViroSeq kit using the ABI PRISM 3,130 sequencer. Results: In this study, 12.26% (394/3,215 of the pregnant women were diagnosed HIV positive. There was 0.52% (2/388 overall vertical transmission of HIV, with rates of 1.75% (2/114 among mothers under prophylaxis and 0.00% (0/274 for those under HAART. Genetic mutations were also isolated that induce resistance to ARV such as M184V, Y115F, K103N, Y181C, V179E, and G190A. There were subtypes and CRF of HIV-1 present, the most common being: CRF06_CPX (58.8%, CRF02_AG (35.3%, and subtype G (5.9%. Conclusions: ARV drugs reduce the residual rate of HIV vertical transmission. However, the virus has developed resistance to ARV, which could limit future therapeutic options when treatment is needed. Resistance to ARV therefore requires a permanent interaction between researchers, physicians, and pharmacists, to strengthen the network of monitoring and surveillance of drug resistance in Burkina Faso.

  15. Local Stability of AIDS Epidemic Model Through Treatment and Vertical Transmission with Time Delay

    Science.gov (United States)

    Novi W, Cascarilla; Lestari, Dwi

    2016-02-01

    This study aims to explain stability of the spread of AIDS through treatment and vertical transmission model. Human with HIV need a time to positively suffer AIDS. The existence of a time, human with HIV until positively suffer AIDS can be delayed for a time so that the model acquired is the model with time delay. The model form is a nonlinear differential equation with time delay, SIPTA (susceptible-infected-pre AIDS-treatment-AIDS). Based on SIPTA model analysis results the disease free equilibrium point and the endemic equilibrium point. The disease free equilibrium point with and without time delay are local asymptotically stable if the basic reproduction number is less than one. The endemic equilibrium point will be local asymptotically stable if the time delay is less than the critical value of delay, unstable if the time delay is more than the critical value of delay, and bifurcation occurs if the time delay is equal to the critical value of delay.

  16. Vertical transitions between transmission lines and waveguides in multilayer liquid crystal polymer (LCP) substrates

    Science.gov (United States)

    Zhang, Yifei; Shi, Shouyuan; Martin, Rick D.; Prather, Dennis W.

    2014-03-01

    In this paper we present two vertical transitions, in multilayer LCP substrates for millimeter wave (mmW) imaging application. The first transition is from conductor-backed co-planar waveguide (CBCPW) to strip line, and the second one connects CBCPW to substrate integrated waveguide (SIW). The multilayer structure consists of three LCP layers and four metal claddings. The CBCPW is designed on the top LCP layer, the strip line is sandwiched by the top and middle layers, and the SIW is built within the middle and bottom layers. Micro vias construct the side wall for the SIW, and electrically connect the transmission lines and waveguides. Both of the transitions perform low loss and low reflection at 77 GHz. They can efficiently connect the passive and active components in the front-end RF module of our mmW imager. Additionally, they may have promising application in high-performance systems, requiring high density, low size, weight, and power (SWaP).

  17. Transmission of vertical stress in a real soil profile. Part II

    DEFF Research Database (Denmark)

    Lamandé, Mathieu; Schjønning, Per

    2011-01-01

    We urgently need increased quantitative knowledge about stress transmission in real soils that suffer heavy loads of agricultural machinery. 3D measurements of vertical stresses under tracked wheels were performed in situ in an annually ploughed Stagnic Luvisol continuously cropped with small grain...... used rated tyre inflation pressures for traffic in the field (≤10 km h−1 driving speed). Seven load cells were inserted horizontally from a pit with minimal disturbance of soil at each of three depths (0.3, 0.6 and 0.9 m), covering the width of the wheeled area. The position of the wheel relative to...... cereals. The tests took place in the spring at field capacity when the topsoil had not been tilled for 1 1/2 years. Two Nokian ELS Radial-ply tyres (800/50R34 and 560/45R22.5) were loaded with two specific loads (30 kN and 60 kN), leading to four treatments labelled 800-30, 800-60, 560-30 and 560-60. We...

  18. Deciphering transmissivity and hydraulic conductivity of the aquifer by vertical electrical sounding (VES) experiments in Northwest Bangladesh

    Science.gov (United States)

    Sattar, Golam Shabbir; Keramat, Mumnunul; Shahid, Shamsuddin

    2016-03-01

    The vertical electrical soundings (VESs) are carried out in 24 selective locations of Chapai-Nawabganj area of northwest Bangladesh to determine the transmissivity and hydraulic conductivity of the aquifer. Initially, the transmissivity and hydraulic conductivity are determined from the pumping data of nearby available production wells. Afterwards, the T and K are correlated with geoelectrical resistance and the total resistivity of the aquifer. The present study deciphers the functional analogous relations of the geoelectrical resistance with the transmissivity and the total resistivity with the hydraulic conductivity of the aquifer in northwest Bangladesh. It has been shown that the given equations provide reasonable values of transmissivity and hydraulic conductivity where pumping test information is unavailable. It can be expected that the aquifer properties viz. transmissivity and hydraulic conductivity of geologically similar area can be determined with the help of the obtained equations by conducting VES experiments.

  19. Vertical transmission of HIV-1 in the western region of the State of São Paulo

    Directory of Open Access Journals (Sweden)

    Vera Lúcia Maria Alves Gonçalves

    2011-02-01

    Full Text Available INTRODUCTION: This study aimed to determine the prevalence of vertical HIV-1 transmission in the western region of the State of São Paulo, Brazil. METHODS: The study analyzed the medical records of HIV-1-infected mothers and infant pairs living in the municipalities of São Paulo Regional Health Departments DRS II (Araçatuba and DRS XI (Presidente Prudente. From March 2001 to March 2006, blood samples were collected and referred to the Molecular Biology Unit of the Adolfo Lutz Institute (ALI, Presidente Prudente. HIV-1-RNA viral load was determined by bDNA assay. RESULTS: The number of births (109/217, 50.2% and vertical HIV-1 transmissions (6/109, 5.5% that occurred in DRS II was similar to births (108/217, 49.8% and vertical transmissions (7/108, 6.5% in DRS XI (p > 0.05. Although 80% (4/5 of the infected children were male in DRS II, while in DRS XI, 75% (6/8 were female, no differences between sex regarding infected and noninfected children in the regions of Araçatuba and Presidente Prudente were verified. The overall vertical HIV-1 transmission rate was 6%. No consistent reduction in the prevalence of vertical HIV-1 transmission occurred over the years. About 20% of mothers did not know the HIV-1 status of their newborns eight months after delivery. CONCLUSIONS: In the present study, MTCT prevalence rates were about 70% higher than those previously determined in the State of São Paulo, with noreduction throughout the period.Furthermore, a significant number of mothers did not know the HIV-status of their newborns eight months after delivery.

  20. Vertical transmission of Mycoplasma wenyonii in cattle, supported by analysis of the ribonuclease P RNA gene - Short communication.

    Science.gov (United States)

    Sasaoka, Fumina; Suzuki, Jin; Hirata, Toh-Ichi; Ichijo, Toshihiro; Furuhama, Kazuhisa; Harasawa, Ryô; Satoh, Hiroshi

    2015-09-01

    The vertical transmission of Mycoplasma (M.) wenyonii was investigated in beef cattle raised on a farm in Japan by analysing the ribonuclease P RNA (rnpB) gene sequence using PCR. Peripheral blood samples from 17 dams infected with M. wenyonii and from their neonatal calves were collected and colostrum samples were taken from cows immediately after parturition, and subsequently the blood samples of calves were monitored continuously for three months. At birth on day 0, although no rnpB gene was detected in the colostrum of any of the dams, four (23.5%) of the 17 calves born were positive. At three months after delivery, the number of positive calves decreased to three. Although horizontal transmission by blood-feeding arthropod vectors has been basically accepted as the most common route of haemoplasma infection, these findings suggest that vertical transmission is, at least in part, another most likely route of M. wenyonii infection in cattle. PMID:26551417

  1. High-pass filtering and dynamic gain regulation enhance vertical bursts transmission along the mossy fiber pathway of cerebellum

    Directory of Open Access Journals (Sweden)

    Jonathan Mapelli

    2010-05-01

    Full Text Available Signal elaboration in the cerebellum mossy fiber input pathway presents controversial aspects, especially concerning gain regulation and the spot-like (rather than beam-like appearance of granular-to-molecular layer transmission. By using voltage-sensitive dye (VSD imaging in rat cerebellar slices (Mapelli et al., 2010, we found that mossy fiber bursts optimally excited the granular layer above ~50 Hz and the overlaying molecular layer above ~100 Hz, thus generating a cascade of high-pass filters. NMDA receptors enhanced transmission in the granular, while GABA-A receptors depressed transmission in both the granular and molecular layer. Burst transmission gain was controlled through a dynamic frequency-dependent involvement of these receptors. Moreover, while high-frequency transmission was enhanced along vertical lines connecting the granular to molecular layer, no high-frequency enhancement was observed along the parallel fiber axis in the molecular layer. This was probably due to the stronger effect of Purkinje cell GABA-A receptor-mediated inhibition occurring along the parallel fibers than along the granule cell axon ascending branch. The consequent amplification of burst responses along vertical transmission lines could explain the spot-like activation of Purkinje cells observed following punctuate stimulation in vivo .

  2. Sero-prevalence of hepatitis B virus and risk analysis of vertical transmission among pregnant women attending the obstetrics and gynecology hospital, Chennai (Tamilnadu, India

    Directory of Open Access Journals (Sweden)

    Anusha Raaj

    2016-01-01

    Conclusions: Prevalence of HBV in pregnant women was found to be high compared to general population reported earlier. LSCS had independent risk factor on vertical transmission than any other risk factors. Therefore, LSCS may not be advisable in HBsAg-positive pregnant women to prevent vertical transmission of HBV. [Int J Reprod Contracept Obstet Gynecol 2016; 5(1.000: 170-174

  3. RISK FACTORS OF HIV-1 VERTICAL TRANSMISSION (VT AND THE INFLUENCE OF ANTIRETROVIRAL THERAPY (ART IN PREGNANCY OUTCOME

    Directory of Open Access Journals (Sweden)

    Maria F.M. Barral

    2014-04-01

    Full Text Available In the absence of intervention, the rate of vertical transmission of HIV can range from 15-45%. With the inclusion of antiretroviral drugs during pregnancy and the choice of delivery route this amounts to less than 2%. However ARV use during pregnancy has generated several questions regarding the adverse effects of the gestational and neonatal outcome. This study aims to analyze the risk factors for vertical transmission of HIV-1 seropositive pregnant women living in Rio Grande and the influence of the use of ARVs in pregnancy outcome. Among the 262 pregnant women studied the rate of vertical transmission of HIV was found to be 3.8%. Regarding the VT, there was a lower risk of transmission when antiretroviral drugs were used and prenatal care was conducted at the referral service. However, the use of ART did not influence the outcome of pregnancy. However, initiation of prenatal care after the first trimester had an influence on low birth weight, as well as performance of less than six visits increased the risk of prematurity. Therefore, the risk factors analyzed in this study appear to be related to the realization of inadequate pre-natal and maternal behavior.

  4. Mouse model of congenital infection with a non-virulent Toxoplasma gondii strain: Vertical transmission, "sterile" fetal damage, or both?

    Science.gov (United States)

    Vargas-Villavicencio, J A; Cedillo-Peláez, C; Rico-Torres, C P; Besné-Mérida, A; García-Vázquez, F; Saldaña, J I; Correa, D

    2016-07-01

    Congenital transmission of Toxoplasma gondii may occur if the mother gets infected for the first time while pregnant. The risk of mother-to-child transmission depends on the gestation trimester at infection, being lowest in the first and highest in the last. Conversely, fetal damage is frequent and more severe at the beginning of pregnancy. The objective of this study was to evaluate congenital transmission and pathological aspects in the placenta and the fetus using a mouse model of congenital infection of the second gestation third. Forty-five female BALB/c mice were infected intravenously with 2.5-10.0 × 10(6) tachyzoites of the ME49 strain at middle gestation. Samples of maternal spleen and fetal/placental units were taken 72 h later. We determined parasite load and vertical transmission by qPCR, as well as damage macroscopically and by histopathology. With the lowest dose, 18% of the fetuses were infected. Also, 40% of fetuses/litter were altered, while this value was 10% in the control group (P < 0.05). These results are similar to those described in humans in terms of vertical transmission and fetal damage during the second third of gestation. The maternal spleen had 10-1000 times more tachyzoites than the placenta, and the later retained 90-99% of the parasites that could reach the fetus. Nevertheless, we found resorptions, abortions or fetal tissue damage in the presence but also in the absence of parasites. Our data indicate a strong protective effect of maternal organs and the placenta against fetal infection, but extensive damage of the later may led to resorption or abortion without vertical transmission. PMID:27068784

  5. Vertical Transmission Lines in Multilayer Substrates and Highly-Integrated Filtering Components Based on These Transmission Lines

    OpenAIRE

    Kushta, Taras

    2010-01-01

    In this chapter, advantages of shield vias disposed in a multilayer substrate at the higher frequencies have been shown. These structures have low leakage losses, well-controlled characteristic impedance and definite propagation constant. Presented physical model for the electromagnetic behavior of the shield via is consistent with results obtained by simulations and measurements and can be used for optimum design of vertical transitions in multilayer substrates for high-speed and high-freque...

  6. Comorbidities in children and adolescents with AIDS acquired by HIV vertical transmission in Vitoria, Brazil.

    Directory of Open Access Journals (Sweden)

    Sandra F Moreira-Silva

    Full Text Available BACKGROUND: Studying diseases associated with AIDS is essential for establishing intervention strategies because comorbidities can lead to death. The objectives were to describe the frequency of comorbidities and verify their distribution according to demographic, epidemiological and clinical data as well as to classify diseases in children and adolescents with AIDS in Vitória, Brazil. METHODS: A retrospective cohort study was conducted among children with AIDS, as defined according to the criteria established by the Ministry of Health, who acquired HIV via vertical transmission, were aged 0 to 18 years, and were monitored at a referral hospital from January 2001 to December 2011. RESULTS: A total of 177 patients were included, of whom 97 were female (55%. There were 60 patients (34% <1 year old, 67 patients (38% between the ages of 1 and 5, and 50 patients (28% ≥6 years of age included at the time of admission to the Infectious Diseases Ward. Regarding clinical-immunological classification, 146 patients (82.5% showed moderate/severe forms of the disease at the time of admission into the Ward, and 26 patients (14.7% died during the study. The most common clinical signs were hepatomegaly (81.62%, splenomegaly (63.8%, lymphadenopathy (68.4% and persistent fever (32.8%. The most common comorbidities were anaemia (67.2%, pneumonia/septicaemia/acute bacterial meningitis (ABM (64.2%, acute otitis media (AOM/recurrent sinusitis (55.4%, recurrent severe bacterial infections (47.4% and dermatitis (43.1%. An association between severe clinical-immunological classification and admission to the Ward for children aged less than one year old was found for several comorbidities (p<0.001. CONCLUSION: Delayed diagnosis was observed because the majority of patients were admitted to the Infectious Diseases Ward at ≥1 year of age and were already presenting with serious diseases. The general paediatrician should be alert to this possibility to make an early

  7. Avaliação dos fatores associados à transmissão vertical de HIV-1

    Directory of Open Access Journals (Sweden)

    Matheus Costa da Rosa

    2015-12-01

    Full Text Available Resumo Objetivo Comparar a prevalência e os fatores associados à transmissão vertical de HIV-1 entre grávidas tratadas de 1998-2004 e de 2005-2011 em um serviço de referência de cuidado de pacientes com HIV no sul do Brasil. Métodos Estudo descritivo e analítico que usou as bases de dados de laboratórios da Rede Nacional de Laboratórios de CD4 e Carga Viral de DST/Aids do Ministério da Saúde. As grávidas com HIV-1 foram selecionadas em uma pesquisa ativa de informações clínicas e dados obstétricos e neonatais em seus prontuários médicos entre 1998-2011. Resultados Foram analisadas 102 grávidas entre 1998 e 2004 e 251 entre 2005-2011, no total 353 crianças nascidas de grávidas com HIV-1. Observou-se que a transmissão vertical foi de 11,8% entre 1998 e 2004 e de 3,2% entre 2005-2011 (p < 0,001. O maior uso de medicamentos antirretrovirais (p = 0,02, a redução na carga viral (p < 0,001 e o tempo de ruptura de membranas menor do que quatro horas (p < 0,001 foram associados à redução nos fatores de transmissão vertical quando os dois períodos são comparados. Conclusão Observou-se uma redução na taxa de transmissão vertical nos últimos anos. De acordo com as variáveis estudadas, sugere-se que os fatores de risco de transmissão vertical de HIV-1 foram ausência de terapia antirretroviral, alta carga viral das grávidas e tempo de ruptura maior do que quatro horas.

  8. Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission.

    Science.gov (United States)

    Tian, Yongjun; Kuo, Cheng-Fu; Akbari, Omid; Ou, Jing-Hsiung James

    2016-05-17

    In contrast to horizontal transmission of hepatitis B virus (HBV) between adults, which often leads to self-limited acute infection, vertical transmission of HBV from mother to child often leads to chronic infection. However, the mechanisms linking vertical transmission with chronic infection are not known. We developed a mouse model to study the effect of maternal HBV infection on HBV persistence in offspring and found that HBV carried by the mother impaired CD8(+) T cell responses to HBV in her offspring, resulting in HBV persistence. This impairment of CD8(+) T cell responses was mediated by hepatic macrophages, which were predisposed by maternal HBV e antigen (HBeAg) to support HBV persistence by upregulation of inhibitory ligand PD-L1 and altered polarization upon restimulation with HBeAg. Depletion of hepatic macrophages led to CD8(+) T cell activation and HBV clearance in the offspring, raising the possibility of targeting macrophages to treat chronic HBV patients. PMID:27156385

  9. From parent to gamete: vertical transmission of Symbiodinium (Dinophyceae ITS2 sequence assemblages in the reef building coral Montipora capitata.

    Directory of Open Access Journals (Sweden)

    Jacqueline L Padilla-Gamiño

    Full Text Available Parental effects are ubiquitous in nature and in many organisms play a particularly critical role in the transfer of symbionts across generations; however, their influence and relative importance in the marine environment has rarely been considered. Coral reefs are biologically diverse and productive marine ecosystems, whose success is framed by symbiosis between reef-building corals and unicellular dinoflagellates in the genus Symbiodinium. Many corals produce aposymbiotic larvae that are infected by Symbiodinium from the environment (horizontal transmission, which allows for the acquisition of new endosymbionts (different from their parents each generation. In the remaining species, Symbiodinium are transmitted directly from parent to offspring via eggs (vertical transmission, a mechanism that perpetuates the relationship between some or all of the Symbiodinium diversity found in the parent through multiple generations. Here we examine vertical transmission in the Hawaiian coral Montipora capitata by comparing the Symbiodinium ITS2 sequence assemblages in parent colonies and the eggs they produce. Parental effects on sequence assemblages in eggs are explored in the context of the coral genotype, colony morphology, and the environment of parent colonies. Our results indicate that ITS2 sequence assemblages in eggs are generally similar to their parents, and patterns in parental assemblages are different, and reflect environmental conditions, but not colony morphology or coral genotype. We conclude that eggs released by parent colonies during mass spawning events are seeded with different ITS2 sequence assemblages, which encompass phylogenetic variability that may have profound implications for the development, settlement and survival of coral offspring.

  10. Vertical Energy and Momentum Fluxes in the Centre of Athens, Greece During a Heatwave Period (Thermopolis 2009 Campaign)

    Science.gov (United States)

    Rapsomanikis, S.; Trepekli, A.; Loupa, G.; Polyzou, C.

    2015-03-01

    The atmospheric energy budget in the centre of Athens, Greece was determined during the Thermopolis 2009 campaign in order to investigate the development of the urban heat island. Heatwaves during summer are a common occurrence in this large conurbation. Micrometeorological data from a tower were acquired in a densely built central district, and net all-wave radiation, sensible heat, latent heat and momentum flux densities were derived by the eddy-covariance method and also estimated using Monin-Obukhov similarity relationships. Under the prevailing hot and dry conditions, sensible heat-flux density was on average five times larger than the latent heat-flux density. The anthropogenic contribution to the energy budget was also determined on the basis of the acquired data.

  11. Repurposing of antiparasitic drugs: the hydroxy-naphthoquinone buparvaquone inhibits vertical transmission in the pregnant neosporosis mouse model.

    Science.gov (United States)

    Müller, Joachim; Aguado-Martínez, Adriana; Manser, Vera; Wong, Ho Ning; Haynes, Richard K; Hemphill, Andrew

    2016-01-01

    The three anti-malarial drugs artemiside, artemisone, and mefloquine, and the naphthoquinone buparvaquone known to be active against theileriosis in cattle and Leishmania infections in rodents, were assessed for activity against Neospora caninum infection. All four compounds inhibited the proliferation of N. caninum tachyzoites in vitro with IC50 in the sub-micromolar range, but artemisone and buparvaquone were most effective (IC50 = 3 and 4.9 nM, respectively). However, in a neosporosis mouse model for cerebral infection comprising Balb/c mice experimentally infected with the virulent isolate Nc-Spain7, the three anti-malarial compounds failed to exhibit any activity, since treatment did not reduce the parasite burden in brains and lungs compared to untreated controls. Thus, these compounds were not further evaluated in pregnant mice. On the other hand, buparvaquone, shown earlier to be effective in reducing the parasite load in the lungs in an acute neosporosis disease model, was further assessed in the pregnant mouse model. Buparvaquone efficiently inhibited vertical transmission in Balb/c mice experimentally infected at day 7 of pregnancy, reduced clinical signs in the pups, but had no effect on cerebral infection in the dams. This demonstrates proof-of-concept that drug repurposing may lead to the discovery of an effective compound against neosporosis that can protect offspring from vertical transmission and disease. PMID:26883424

  12. [Incidence of congenital syphilis and factors associated with vertical transmission: data from the Birth in Brazil study].

    Science.gov (United States)

    Domingues, Rosa Maria Soares Madeira; Leal, Maria do Carmo

    2016-06-20

    The objectives were to estimate incidence of congenital syphilis and verify factors associated with vertical transmission. A national hospital-based study was performed in 2011-2012 with 23,894 postpartum women using an in-hospital interview and data from patient charts and prenatal cards. Univariate logistic regression was performed to verify factors associated with congenital syphilis. Estimated incidence of congenital syphilis was 3.51 per 1,000 live births (95%CI: 2.29-5.37) and vertical transmission rate was 34.3% (95%CI: 24.7-45.4). Congenital syphilis was associated with lower maternal schooling, black skin color, higher rate of risk factors for prematurity, late initiation of prenatal care, fewer prenatal visits, and lower rate of prenatal serological testing. Fetal mortality was six times higher in congenital syphilis, and newborns with congenital syphilis showed higher hospital admission rates. Congenital syphilis is a persistent public health problem in Brazil and is associated with greater social vulnerability and gaps in prenatal care. PMID:27333146

  13. Vertical transmission of hepatitis C virus in a hospital in southern Brazil Transmissão vertical do vírus da hepatite C em um hospital do sul do Brasil

    Directory of Open Access Journals (Sweden)

    Mário Ferreira Peixoto

    2004-06-01

    Full Text Available BACKGROUND: There still are controversies concerning the vertical transmission of hepatitis C virus. AIM: To evaluate the prevalence of antibodies against hepatitis C virus in pregnant women, as well as the rate of vertical transmission of this virus. PATIENTS AND METHODS: Between August 1998 and November 1999, 1,090 consecutive pregnant women were screened for anti-hepatitis C virus; positive results were confirmed by the polymerase chain reaction assay. Patient's viral load was evaluated by the branched deoxyribonucleic acid assay. Hepatitis C virus genotype was identified by direct sequencing of the polymerase chain reaction amplification products. The same tests were performed in the children born from infected mothers at the 1st and 6th month of life. RESULTS: Of the 1,090 mothers surveyed, 29 were positive for anti-hepatitis C virus (prevalence of 2.66%. Twenty-five patients presented with hepatitis C virus RNA, with a median hepatitis C virus viral load of 3.132 ± 5.891 MEq/mL. Twenty-two patients (six human immunodeficiency virus-coinfected were followed and gave birth to 23 children; 18 of them had blood samples tested at the 1st month of life, and 22, at the 6th month. Vertical transmission rate was 5.56%; it affected a girl who had hepatitis C virus RNA detectable only in the 1st month sample (41.570 MEq/mL. The mother who transmitted hepatitis C virus was coinfected with human immunodeficiency virus and presented with an hepatitis C virus viral load of 3.765 MEq/mL, with 100% homology with her daughter's hepatitis C virus genotype. CONCLUSION: These results suggest that the prevalence of hepatitis C virus infection in pregnant women should not be neglected, and early diagnosis of vertical transmission and the follow up of infected children should be emphasized.RACIONAL: Ainda existem controvérsias em relação à transmissão vertical do vírus da hepatite C (VHC. OBJETIVO: Avaliar a prevalência dos anticorpos contra o VHC (anti

  14. RELIABILITY ASSESSMENT OF TRANSMISSION TOWER OF 220 KV M/C “MA” VERTICAL MEMBERS

    Directory of Open Access Journals (Sweden)

    M.V.R.SATYANARAYANA

    2014-04-01

    Full Text Available Transmission line towers are used to support conductors carrying extra high voltage (EHV electric transmission lines and one or two ground wires at suitable distance. These also carry vary heavy currents, to the tune of several hundred amperes. This has necessitated the use of tall towers to support the transmission line conductors carrying EHV. The cost of transmission line tower is 30% to 40% of total cost of transmission line. The problem of efficiently designing structural system involves reliability constraints imposed at both serviceability and ultimate limit state. Methods are developed using structural reliability principle to evaluate time dependent reliability of structure. These methods enable the impact on safety and serviceability of uncertainties in loading conditions, structural degradation due to aggressive environment to be assessed qualitatively. The prediction of service life of damaged or deteriorated steel structures remains at the stage of parametric studies, inspite of intensive research on corrosion in steel structures for the past three decades. Service live of steel structures is limited by the susceptibility of the member to corrosion. Oxidation of iron leads to the formulation of various products (such as ferrous and ferric oxides, some of which occupy much greater volume than the original iron that gets consumed by the corrosion process. At this stage the member loses its ability to resist the forces. This project is a study on reliability assessment of 220 kV transmission towers. In this the 220 kV tower consists of 33.935 m height arranged in 12 height Panels and it contain 225 members. The wind load on tower for zone –II condition is calculated according to IS Code IS: 802 (part – 1/Section – 1: 1995. The tower is analyzed as space truss for full load condition using STAAD Pro 2007. In this work the variation of reliability index of members with decrease in area of cross section are studied. The compression

  15. Trypanosoma brucei gambiense Infections in Mice Lead to Tropism to the Reproductive Organs, and Horizontal and Vertical Transmission.

    Science.gov (United States)

    Biteau, Nicolas; Asencio, Corinne; Izotte, Julien; Rousseau, Benoit; Fèvre, Muriel; Pillay, Davita; Baltz, Théo

    2016-01-01

    Trypanosoma brucei gambiense, transmitted by the tsetse fly, is the main causative agent of Human African trypanosomosis in West Africa and poses a significant health risk to 70 million people. Disease progression varies depending on host immunity, but usually begins with a haemo-lymphatic phase, followed by parasite invasion of the central nervous system. In the current study, the tropism of T. b. gambiense 1135, causing a low level chronic 'silent' infection, was monitored in a murine model using bioluminescence imaging and PCR. A tropism to the reproductive organs, in addition to the central nervous system, after 12-18 months of infection was observed. Bioluminescent analysis of healthy females crossed with infected males showed that 50%, 62.5% and 37.5% of the female mice were subsequently positive for parasites in their ovaries, uteri and brain respectively. Although PCR confirmed the presence of parasites in the uterus of one of these mice, the blood of all mice was negative by PCR and LAMP. Subsequently, bioluminescent imaging of the offspring of infected female mice crossed with healthy males indicated parasites were present in the reproductive organs of both male (80%) and female (60%) offspring. These findings imply that transmission of T. b. gambiense 1135 occurs horizontally, most probably via sexual contact, and vertically in a murine model, which raises the possibility of a similar transmission in humans. This has wide reaching implications. Firstly, the observations made in this study are likely to be valid for wild animals acting as a reservoir for T. b. gambiense. Also, the reproductive organs may act as a refuge for parasites during drug treatment in a similar manner to the central nervous system. This could leave patients at risk of a relapse, ultimately allowing them to act as a reservoir for subsequent transmission by tsetse and possibly, horizontally and vertically. PMID:26735855

  16. Vertical transmission explains the specific Burkholderia pattern in Sphagnum mosses at multi-geographic scale

    OpenAIRE

    AnastasiaBragina; ChristianBerg

    2013-01-01

    The betaproteobacterial genus Burkholderia is known for its versatile interactions with its hosts that can range from beneficial to pathogenic. A plant-beneficial-environmental (PBE) Burkholderia cluster was recently separated from the pathogen cluster, yet still little is known about burkholderial diversity, distribution, colonization, and transmission patterns on plants. In our study, we applied a combination of high-throughput molecular and microscopic methods to examine the aforementioned...

  17. Role of trade-off between sexual and vertical routes for evolution of pathogen transmission

    Czech Academy of Sciences Publication Activity Database

    Bernhauerová, V.; Berec, Luděk

    2015-01-01

    Roč. 8, č. 1 (2015), s. 23-36. ISSN 1874-1738 Grant ostatní: Masaryk University(CZ) MUNI/A/0849/2012 Institutional support: RVO:60077344 Keywords : adaptive dynamics * frequency-dependent transmission * infectious disease Subject RIV: EH - Ecology, Behaviour Impact factor: 1.553, year: 2014 http://link.springer.com/article/10.1007%2Fs12080-014-0234-8

  18. Vertical Transmission of Endobacteria in the Arbuscular Mycorrhizal Fungus Gigaspora margarita through Generation of Vegetative Spores

    OpenAIRE

    V Bianciotto; Genre, A.; Jargeat, P.; Lumini, E; Bécard, G.; Bonfante, P.

    2004-01-01

    Arbuscular mycorrhizal (AM) fungi living in symbiotic association with the roots of vascular plants have also been shown to host endocellular rod-shaped bacteria. Based on their ribosomal sequences, these endobacteria have recently been identified as a new taxon, Candidatus Glomeribacter gigasporarum. In order to investigate the cytoplasmic stability of the endobacteria in their fungal host and their transmission during AM fungal reproduction (asexual), a system based on transformed carrot ro...

  19. Transmission electron microscopy study of vertical quantum dots molecules grown by droplet epitaxy

    International Nuclear Information System (INIS)

    The compositional distribution of InAs quantum dots grown by molecular beam epitaxy on GaAs capped InAs quantum dots has been studied in this work. Upper quantum dots are nucleated preferentially on top of the quantum dots underneath, which have been nucleated by droplet epitaxy. The growth process of these nanostructures, which are usually called as quantum dots molecules, has been explained. In order to understand this growth process, the analysis of the strain has been carried out from a 3D model of the nanostructure built from transmission electron microscopy images sensitive to the composition.

  20. [On the possibility of vertical transmission of Trichinella and the impact of its invasion].

    Science.gov (United States)

    Odoevskaia, I M

    2014-01-01

    Whether experimentally infected female rats can transmit Trichinella in utero and its invasion may affect the immunity of their offspring has been investigated. There is evidence that maternal antibodies have a significant impact on the humoral immunity of the offspring and as a result on the number of Trichinella larvae accustomed in the muscles. Immune interlayer formation in the populations of carnivorous mammals in the endemic areas occurs due to reinvasions and passive transmission of maternal antibodies to the offspring. High-tension immunity in the population and animals contributes to a reduction in the onset of invasion and to a predominance of the subclinical course of the disease and asymptomatic carriage in a specific focus. Passive immunity transmitted from the Trichinella-infected mother to its offspring is of importance in the development of epidemic and epizootic processes in the natural and synanthropic foci of trichinosis. PMID:25812404

  1. Barriers to control syphilis and HIV vertical transmission in the health care system in the city of Sao Paulo

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    Valdete Maria Ramos

    2014-12-01

    Full Text Available OBJECTIVE: The objective of this study was to identify possible barriers to control vertical transmission of syphilis and HIV through the analysis of the orientation process of pregnant women from prenatal care to the obstetric center at an university hospital in Sao Paulo (Reference and their return (with their exposed babies for follow-up after hospital discharge (counter-reference. METHODS: It is a retrospective cross-sectional study including interviews with healthcare personnel. Pregnant women with syphilis and/or HIV-infection admitted for labor or miscarriage were identified from August 2006 to August 2007. Routine care for mothers and babies were analyzed. RESULTS: 56 pregnant women were identified: 43 were HIV-infected, 11 had syphilis and two were coinfected (syphilis/HIV; 22 health care professionals were interviewed. Prenatal care was identified in 91.1% of these women: 7/11 (63.6% with syphilis; 44/45 (97.8% HIV-infected or coinfected. The reference for delivery was satisfactory for 57.7% of the syphilis-infected women and 97.7% of the HIV-infected ones. The counter-reference was satisfactory for all babies and mothers at hospital discharge, besides the non-adherence to this recommendation. Interviews with health care professionals showed there are better routines for assisting and following-up pregnant women, puerperal women and HIV-infected or exposed babies than for those infected with syphilis. The epidemiological report and surveillance system are also better for HIV-infected patients. CONCLUSION: The difficulties in the reference and counter-reference system of these women and their babies are evident barriers to control the vertical transmission of these infectious diseases.

  2. Maternidade e projetos vitais em jovens infectadas com HIV por transmissão vertical

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    Ana Paula Eid, Brasil

    2015-07-01

    Full Text Available (analítico Este artículo relata una investigación cualitativa con el objetivo de analizar a través de entrevistas narrativas, autobiográficas, cómo los jóvenes VIH positivos, infectadas con trasmisión vertical, construyen sus proyectos de vida y sobretodo de maternidad. El análisis de las entrevistas se basó teóricamente en Análisis Crítico del Discurso (ACD. Emergieron dos ejes de discusión: Proyecto Vital y Maternidad. Las narrativas apuntan hacia una construcción de proyecto vital basadas en cuatro elementos complementarios: estudio, trabajo, conyugalidad y futuro. El eje discursivo Maternidad, se comprehende a través de seis elementos clave: la maternidad, embarazo planeado y no planeado, parto y puerperio, la lactancia, El VIH versus hijo(a sano(a y culpa y responsabilidad. Factores particulares, como prejuicio, aspiraciones y miedos, atraviesan la cotidianidad de quien vive con VIH/Sida. Las participantes perciben que la sociedad no las considera aptas para crear una familia y luchar por sus proyectos de vida.

  3. Zika Virus Targets Different Primary Human Placental Cells, Suggesting Two Routes for Vertical Transmission.

    Science.gov (United States)

    Tabata, Takako; Petitt, Matthew; Puerta-Guardo, Henry; Michlmayr, Daniela; Wang, Chunling; Fang-Hoover, June; Harris, Eva; Pereira, Lenore

    2016-08-10

    Zika virus (ZIKV) infection during pregnancy is linked to severe birth defects, but mother-to-fetus transmission routes are unknown. We infected different primary cell types from mid- and late-gestation placentas and explants from first-trimester chorionic villi with the prototype Ugandan and a recently isolated Nicaraguan ZIKV strain. ZIKV infects primary human placental cells and explants-cytotrophoblasts, endothelial cells, fibroblasts, and Hofbauer cells in chorionic villi and amniotic epithelial cells and trophoblast progenitors in amniochorionic membranes-that express Axl, Tyro3, and/or TIM1 viral entry cofactors. ZIKV produced NS3 and E proteins and generated higher viral titers in amniotic epithelial cells from mid-gestation compared to late-gestation placentas. Duramycin, a peptide that binds phosphatidylethanolamine in enveloped virions and precludes TIM1 binding, reduced ZIKV infection in placental cells and explants. Our results suggest that ZIKV spreads from basal and parietal decidua to chorionic villi and amniochorionic membranes and that targeting TIM1 could suppress infection at the uterine-placental interface. PMID:27443522

  4. Emergence of minor drug-resistant HIV-1 variants after triple antiretroviral prophylaxis for prevention of vertical HIV-1 transmission.

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    Andrea Hauser

    Full Text Available BACKGROUND: WHO-guidelines for prevention of mother-to-child transmission of HIV-1 in resource-limited settings recommend complex maternal antiretroviral prophylaxis comprising antenatal zidovudine (AZT, nevirapine single-dose (NVP-SD at labor onset and AZT/lamivudine (3TC during labor and one week postpartum. Data on resistance development selected by this regimen is not available. We therefore analyzed the emergence of minor drug-resistant HIV-1 variants in Tanzanian women following complex prophylaxis. METHOD: 1395 pregnant women were tested for HIV-1 at Kyela District Hospital, Tanzania. 87/202 HIV-positive women started complex prophylaxis. Blood samples were collected before start of prophylaxis, at birth and 1-2, 4-6 and 12-16 weeks postpartum. Allele-specific real-time PCR assays specific for HIV-1 subtypes A, C and D were developed and applied on samples of mothers and their vertically infected infants to quantify key resistance mutations of AZT (K70R/T215Y/T215F, NVP (K103N/Y181C and 3TC (M184V at detection limits of <1%. RESULTS: 50/87 HIV-infected women having started complex prophylaxis were eligible for the study. All women took AZT with a median duration of 53 days (IQR 39-64; all women ingested NVP-SD, 86% took 3TC. HIV-1 resistance mutations were detected in 20/50 (40% women, of which 70% displayed minority species. Variants with AZT-resistance mutations were found in 11/50 (22%, NVP-resistant variants in 9/50 (18% and 3TC-resistant variants in 4/50 women (8%. Three women harbored resistant HIV-1 against more than one drug. 49/50 infants, including the seven vertically HIV-infected were breastfed, 3/7 infants exhibited drug-resistant virus. CONCLUSION: Complex prophylaxis resulted in lower levels of NVP-selected resistance as compared to NVP-SD, but AZT-resistant HIV-1 emerged in a substantial proportion of women. Starting AZT in pregnancy week 14 instead of 28 as recommended by the current WHO-guidelines may further increase

  5. Fatores que influenciam a transmissão vertical do vírus da imunodeficiência humana tipo 1 Risk factors for vertical transmission of the human immunodeficiency virus type 1

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    Geraldo Duarte

    2005-11-01

    Full Text Available Um dos mais expressivos avanços visando controlar a dispersão da infecção pelo vírus da imunodeficiência humana tipo 1 (HIV-1 ocorreu no contexto da transmissão vertical (TV, reduzindo-a de cifras que chegavam a 40% para menos de 3%. O progresso tecnológico, aliado ao melhor conhecimento fisiopatológico dessa infecção, permitiu elencar as situações e os fatores que elevam as taxas de transmissão perinatal desse vírus, indicando quais as intervenções mais adequadas para o seu controle. Estas situações de maior risco para a TV do HIV-1 podem ser agrupadas em fatores maternos, anexiais, obstétricos, fetais, virais e pós-natais. Dos fatores maternos destaca-se a carga viral, o principal indicador do risco desta forma de transmissão. No entanto, a despeito da relevância da carga viral, ela não é a única variável desta equação, devendo ser lembrado o uso de drogas ilícitas, parceria sexual múltipla com sexo desprotegido, desnutrição, tabagismo, doença materna avançada e falta de adesão ou de acesso aos anti-retrovirais. Dos fatores anexiais apontam-se a corioamniorrexe prolongada, a perda da integridade placentária e a expressão dos receptores secundários no tecido placentário. Entre os fatores obstétricos deve ser lembrado que intervenções invasivas sobre o feto ou câmara amniótica, cardiotocografia interna, tipo de parto e contato do feto/recém-nascido com sangue materno também são importantes elementos a serem controlados. Dos fatores fetais são citados a expressão de receptores secundários para o HIV-1, a suscetibilidade genética, a função reduzida dos linfócitos T-citotóxicos e a prematuridade. Sobre os fatores virais aventa-se que a presença de mutações e cepas indutoras de sincício sejam fatores de risco para a TV. Finalmente, há os fatores pós-natais, representados pela carga viral elevada no leite, baixa concentração de anticorpos neste fluído, mastite clínica e les

  6. Estratégias que reduzem a transmissão vertical do vírus da imunodeficiência humana tipo 1 Strategies to avoid vertical transmission of human immunodeficiency virus type 1

    Directory of Open Access Journals (Sweden)

    Geraldo Duarte

    2005-12-01

    Full Text Available O conhecimento dos fatores ou situações que influenciam a transmissão vertical (TV do vírus da imunodeficiência humana tipo 1 (HIV-1 levou à adoção de estratégias com redução de taxas ao longo dos anos: de 40% para menos de 3% na atualidade. Um dos maiores avanços foi o uso profilático da zidovudina (AZT, administrada durante o pré-natal (via oral, no período anteparto (via endovenosa e ao recém-nascido (via oral. Esta intervenção reduz a TV do HIV-1 em 68%, fazendo com que seja considerada a estratégia isolada de maior efetividade. Na seqüência cronológica dos avanços, observou-se que a carga viral elevada é o principal indicador do risco para esta forma de transmissão. Como o AZT não reduz a carga viral e não consegue controlar a taxa residual observada na TV do HIV-1, a utilização dos esquemas profiláticos utilizando três anti-retrovirais foi objetivamente impulsionada. Completando o ciclo das estratégias obstétricas de maior impacto na redução da TV do HIV-1 está a cesárea eletiva, cuja efetividade está ligada à observação dos critérios de sua indicação: carga viral aferida após a 34ª semana de gravidez apresentando contagem maior que 1000 cópias/ml, gestação com mais de 38 semanas confirmada por ultra-sonografia, membranas corioamnióticas íntegras e fora de trabalho de parto. Nos casos em que a via de parto tem indicação obstétrica, deve ser lembrado que a corioamniorrexe prolongada, manobras invasivas sobre o feto, parto instrumentalizado e a episiotomia são situações que devem ser evitadas. Das intervenções pós-natais consideradas importantes para a redução da TV do HIV-1 são apontadas a recepção pediátrica (deve ser efetivada por profissional treinado evitando microtraumatismos de mucosa nas manobras aspirativas, utilização do AZT neonatal (por período de seis semanas e a amamentação artificial. Especial atenção deve ser dispensada às orientações para as nutrizes

  7. Mode of delivery and the risk of vertical HIV transmission%分娩方式与艾滋病母婴传播

    Institute of Scientific and Technical Information of China (English)

    张璐; 王临虹; 方利文

    2012-01-01

    艾滋病病毒(HIV)可通过母亲妊娠分娩传播给新生儿,即艾滋病的母婴传播.艾滋病母婴传播可发生在妊娠、分娩和哺乳的各个过程,但在分娩前后的传播比例最高.分娩过程中产科因素对艾滋病母婴传播风险的影响,特别是不同分娩方式是否会影响艾滋病母婴传播风险,既往一直争议不断.近年来由于抗病毒药物特别是高效抗反转录病毒疗法和人工喂养,已将母婴传播的风险下降到一个较低的水平,越来越多的研究者已不再倾向将分娩方式选择作为减少艾滋病母婴传播的主要干预措施.%HIV could be transmitted from mother to child by pregnancy and delivery, which is called vertical HIV transmission. Vertical transmission can occur during pregnancy, childbirth and breast-feeding, but most occurred during labor and delivery or early postpartum period. For many years it has been contentious whether obstetric factors during labor and delivery would affect the risk of transmission, especially different modes of delivery. In recent years, risk of vertical HIV transmission has been reduced to a lower level owing to antiviral drugs, especially highly active antiretroviral therapy (HAART) and artificial feeding. Then more and more researchers questioned the need to reduce vertical transmission by selection of mode of delivery.

  8. BOSS: intelligent embedded video surveillance system with real-time transmission of video to the control centre

    OpenAIRE

    Sanz, D.; DELCOURT,V; GATIN,O; BERBINEAU,M; Ambellouis, S.; Khoudour, L.

    2008-01-01

    This paper presents the European Research Project BOSS, which deals with automatic event detection and real-time video transmission towards control centers in order to develop a more intelligent and efficient embedded video-surveillance system for trains. Firstly, security issues concerning suburban trains in France and the general objectives of the project are introduced. Secondly the railway operator's needs are presented. Then the foreseen work in the domains of real-time video transmissio...

  9. Prevalência de HIV em gestantes e transmissão vertical segundo perfil socioeconômico, Vitória, ES

    Directory of Open Access Journals (Sweden)

    Anne Caroline Barbosa Cerqueira Vieira

    2011-08-01

    Full Text Available OBJETIVO: Descrever a prevalência de infecção por HIV em gestantes e a taxa de transmissão vertical, segundo o perfil socioeconômico dos bairros de residência das mães. MÉTODOS: Estudo ecológico exploratório utilizando a base de dados do Sistema de Informação de Agravos de Notificação de gestantes HIV-positivas e aids em crianças notificadas entre 2000 e 2006 em Vitória, ES. Para análise das informações socioeconômicas foi utilizado o Índice de Qualidade Urbana. A prevalência de HIV em gestantes e a taxa de transmissão vertical foram calculadas. A distribuição espacial dos casos foi realizada no programa Terraview 3.2.0. Para verificar a associação entre a qualidade urbana e a prevalência de HIV em gestantes utilizou-se o modelo de regressão de Poisson. RESULTADOS: Um total de 137 gestantes e 14 crianças infectadas por transmissão vertical foi notificado no período. Sete crianças correspondiam a mães HIV-positivas sem notificação de caso no período analisado. A prevalência de infecção em gestantes no período foi de 0,44% e a taxa de transmissão vertical foi de 9,7%. CONCLUSÕES: A prevalência de infecção por HIV em gestantes e a transmissão vertical associam-se à qualidade urbana do bairro de residência, indicando que os bairros com menor qualidade urbana devem ser priorizados quanto às ações para redução da transmissão vertical.

  10. Possible healthcare-associated transmission as a cause of secondary infection and population structure of Staphylococcus aureus isolates from two wound treatment centres in Ghana.

    Science.gov (United States)

    Kpeli, G; Darko Otchere, I; Lamelas, A; Buultjens, A L; Bulach, D; Baines, S L; Seemann, T; Giulieri, S; Nakobu, Z; Aboagye, S Y; Owusu-Mireku, E; Pluschke, G; Stinear, T P; Yeboah-Manu, D

    2016-09-01

    We have previously shown that secondary infections of Buruli ulcer wounds were frequently caused by Staphylococcus aureus. To gain understanding into possible routes of secondary infection, we characterized S. aureus isolates from patient lesions and surrounding environments across two Ghanaian health centres. One hundred and one S. aureus isolates were isolated from wounds (n = 93, 92.1%) and the hospital environment (n = 8, 7.9%) and characterized by the spa gene, mecA and the Panton-Valentine leucocidin toxin followed by spa sequencing and whole genome sequencing of a subset of 49 isolates. Spa typing and sequencing of the spa gene from 91 isolates identified 29 different spa types with t355 (ST152), t186 (ST88), and t346 dominating. Although many distinct strains were isolated from both health centres, genotype clustering was identified within centres. In addition, we identified a cluster consisting of isolates from a healthcare worker, patients dressed that same day and forceps used for dressing, pointing to possible healthcare-associated transmission. These clusters were confirmed by phylogenomic analysis. Twenty-four (22.8%) isolates were identified as methicillin-resistant S. aureus and lukFS genes encoding Panton-Valentine leucocidin were identified in 67 (63.8%) of the isolates. Phenotype screening showed widespread resistance to tetracycline, erythromycin, rifampicin, amikacin and streptomycin. Genomics confirmed the widespread presence of antibiotic resistance genes to β-lactams, chloramphenicol, trimethoprim, quinolone, streptomycin and tetracycline. Our findings indicate that the healthcare environment probably contributes to the superinfection of Buruli ulcer wounds and calls for improved training in wound management and infection control techniques. PMID:27547406

  11. Transmissão vertical do HIV: situação encontrada em uma maternidade de Teresina Transmisión vertical del HIV: situación encontrada en una maternidade de Teresina Vertical transmission of HIV: situation found in a maternity of Teresina

    Directory of Open Access Journals (Sweden)

    Liliam Mendes de Araújo

    2007-08-01

    Full Text Available Oaumento dos casos de AIDS em mulheres evidencia um progressivo aumento da transmissão vertical do HIV, no Brasil e no Piauí. Considerando a relevância do tema o presente estudo teve como objetivo analisar as condições da implementação das normas e medidas recomendadas pelo Ministério da Saúde para prevenir a transmissão vertical do HIV em uma maternidade de Teresina - PI. O caminho teórico-metodológico compreendeu o estudo da dinâmica organizacional e dos seus atores, por meio de abordagem qualitativa. Para obtenção dos dados foram realizadas 17 entrevistas semi-estruturadas. Os resultados mostraram que as recomendações do Ministério da Saúde não foram atendidas na sua totalidade evidenciando a precariedade da assistência prestada para o binômio mãe/filho.El aumento de los casos de AIDS en mujeres, evidencia un progresivo aumento de la transmisión vertical de lo HIV en el Brasil, e en el Piauí. Considerando la relevancia del tema, el presente estudio tuve como objetivo analizar las condiciones de la implementación de las reglas y medidas recomendadas por el Ministerio de la Salud para prevenir la transmisión vertical del HIV en una maternidad de Teresina-PI. El camino teórico-metodológico comprendió el estudio de la dinámica organizacional y de sus actores, a través del abordaje cualitativa.. Para la obtención de los datos fueran realizados 17 entrevistas medio-estructuradas. Los resultados mostraran que las recomendaciones del Ministerio de la Salud non fueran atendidas en la suya totalidad, evidenciando la precariedad de la asistencia prestada, para el binomio madre / hijo.The increase of the number of cases of AIDS among women reveals a progressive increase of the vertical transmission of HIV in Brazil, as well as in Piauí. Considering the relevance of the subject, this study had as objective to analyze the conditions of the implementation of the rules and measures recommended by the Ministry of Health to

  12. Gestantes portadoras de HIV/AIDS: aspectos psicológicos sobre a prevenção da transmissão vertical

    Directory of Open Access Journals (Sweden)

    Charmênia Maria Braga Cartaxo

    2013-09-01

    Full Text Available A gestação, em geral, repercute emocionalmente na mulher e, mais intensamente, quando associada a uma situação clínica comprometedora da saúde do filho, como na possibilidade de transmissão vertical do HIV. Nesse contexto, o presente estudo teve por objetivo investigar as significações subjetivas das gestantes portadoras de HIV sobre a realização das ações de prevenção da transmissão vertical. Para tanto, recorreu-se a uma investigação do tipo transversal, de natureza descritiva e exploratória, com abordagem qualitativa, da qual, segundo o critério de saturação do conteúdo, participaram 12 gestantes. Os resultados demonstraram que as gestantes têm dificuldades imediatas para aderir aos medicamentos antirretrovirais, relutância em aceitar a possível indicação do parto cesáreo e frustração, permeada por sentimentos de culpa, diante da impossibilidade de amamentação do filho. Observa-se, assim, a necessidade de ações de apoio socioemocional a serem desenvolvidas pelos profissionais de saúde, especialmente os psicólogos, para favorecer o enfrentamento da transmissão vertical.

  13. HIV-1 Vertical Transmission in Zimbabwe in 622 Mother and Infant Pairs: Rethinking the Contribution of Mannose Binding Lectin Deficiency in Africa.

    Science.gov (United States)

    Zinyama-Gutsire, Rutendo B L; Christiansen, Michael; Hedley, Paula L; Rusakaniko, Simbarashe; Hagen, Christian; Stray-Pedersen, Babill; Buzdugan, Raluca; Cowan, Frances; Chasela, Charles

    2016-07-01

    Vertical transmission of human immunodeficiency virus (HIV) remains a major global health problem. We assessed the association of mannose binding lectin (MBL) deficiency and vertical transmission of HIV. Novel diagnostics would be a major breakthrough in this regard. MBL is a liver-derived protein and a key component of the innate immune system. MBL levels may be classified as normal, intermediate, or deficient in the plasma and can use MBL2 haplotypes as a proxy. These haplotypes comprise polymorphisms in the MBL2 gene and promoter region and are known to result in varying levels of MBL deficiency. MBL deficiency can be defined as presence of A/O and O/O genotypes in the mothers and their children. MBL deficiency leads to defective opsonization activities of the innate immune system and increased susceptibility to several infections, including HIV-1. We determined the prevalence of MBL deficiency, using MBL2 haplotypes among 622 HIV-positive Zimbabwean mothers and their children aged 9-18 months old, in relation to the HIV-1 vertical transmission risk. The median age of the mothers was 30 (26-34, interquartile range [IQR]) years, and the babies' median age was 13 (11-15, IQR) months old at the time of enrollment. From the sample of 622 mothers who were HIV-1 infected, 574 babies were HIV negative and 48 were HIV-1-positive babies, giving a transmission rate of 7.7%. MBL2 normal structural allele A and variants B (codon 5 A>G), C (codon 57 A>G), and promoter region SNPs -550(H/L) and -221(X/Y) were detected. Prevalence of haplotype-predicted MBL deficiency was 34% among the mothers and 32% among the children. We found no association between maternal MBL2 deficiency and HIV-1 transmission to their children. We found no difference in the distribution of HIV-1 infected and uninfected children between the MBL2 genotypes of the mothers and those of the children. Taken together, the present study in a large sample of mother-infant pairs in Zimbabwe adds to the

  14. Risk adapted transmission prophylaxis to prevent vertical HIV–1 transmission: Effectiveness and safety of an abbreviated regimen of postnatal oral Zidovudine

    Directory of Open Access Journals (Sweden)

    Neubert Jennifer

    2013-01-01

    Full Text Available Abstract Background Antiretroviral drugs including zidovudine (ZDV are effective in reducing HIV mother to child transmission (MTCT, however safety concern remains. The optimal duration of postnatal ZDV has not been established in clinical studies and there is a lack of consensus regarding optimal management. The objective of this study was to investigate the effectiveness and safety of a risk adapted two week course of oral postnatal ZDV as part of a combined intervention to reduce MTCT. Methods 118 mother infant pairs were treated according to the German-Austrian recommendations for HIV therapy in pregnancy and in HIV exposed newborns between 2000–2010. In the absence of factors associated with an increased HIV–1 transmission risk, children were assigned to the low risk group and treated with an abbreviated postnatal regimen with oral ZDV for 2 weeks. In the presence of risk factors, postnatal ZDV was escalated accordingly. Results Of 118 mother-infant pairs 79 were stratified to the low risk group, 27 to the high risk group and 11 to the very high risk group for HIV–1 MTCT. 4 children were lost to follow up. Overall Transmission risk in the group regardless of risk factors and completion of prophylaxis was 1.8% (95% confidence interval (CI 0.09–6.6. If transmission prophylaxis was complete, transmission risk was 0.9% (95% CI 0.01-5.7. In the low risk group receiving two week oral ZDV transmission risk was 1.4% (95% CI 0.01–8.4 Conclusion These data demonstrate the effectiveness of a short neonatal ZDV regimen in infants of women on stable ART and effective HIV–1 suppression. Further evaluation is needed in larger studies.

  15. Stability and disease persistence in an age-structured SIS epidemic model with vertical transmission and proportionate mixing assumption

    International Nuclear Information System (INIS)

    The stability of the endemic equilibrium of an SIS age-structured epidemic model of a vertically as well as horizontally transmitted disease is investigated when the force of infection is of proportionate mixing assumption type. We also investigate the uniform weak disease persistence. (author)

  16. Effect of hepatitis B vaccination in hepatitis B surface antibody-negative pregnant mothers on the vertical transmission of hepatitis B virus from father to infant

    OpenAIRE

    Cao, Li-hua; LI, YUN-RU; WANG, SHOU-YUN; LIU, ZHI-MIN; SUN, SHAO-CHUN; Xu, Dong-Bo; ZHANG, JI-DONG

    2015-01-01

    The aim of the present study was to investigate the effects of vaccination with the hepatitis B vaccine (HBVac) in HB surface antibody (HBsAb)-negative pregnant mothers on the vertical transmission of HB virus (HBV) from father to infant. All the fathers tested positive for the serum HBV DNA and HB surface antigen (HBsAg) markers. The pregnant females were divided into an observation group or a control group depending on whether their serum was HBsAb-negative or positive. A total of 93 health...

  17. A Sensitive and Rapid Assay for Investigating Vertical Transmission of Hepatitis B Virus via Male Germ Line Using EGFP Vector as Reporter

    Science.gov (United States)

    Ahmed, Mohamed Morsi M.; Huang, Tian-Hua; Xie, Qing-Dong

    2008-01-01

    Hepatitis B virus (HBV) constitutes a serious menace to man. DNA recombination and sequencing, interspecific in vitro fertilization, single-embryo PCR and RT-PCR were employed to establish a sensitive and rapid assay for exploring the vertical transmission of viruses via male germ line. Plasmid pIRES2-EGFP-HBs which expressed enhanced green fluorescent protein as reporter for the expression of hepatitis B virus S gene was successfully constructed and confirmed by PCR, EcoR I and Sal I digestion, and DNA sequencing. After exposure to the plasmid, human spermatozoa were used to fertilize with zona-free hamster ova. Two-cell embryos were collected and classified into group A with green fluorescence and group B without green fluorescence under fluorescence microscope. The results showed that HBs DNA positive bands were detected in the embryos with green fluorescence (PCR and RT-PCR) and positive control (PCR) indicating expression of pIRES2-EGFP-HBs, and not observed in the embryos without green fluorescence and negative controls (PCR and RT-PCR) indicating no pIRES2-EGFP-HBs in the cells. The advantages and application foreground of this assay for study on vertical transmission of viruses such as HCV, HIV, HPV, and SARS via germ line were discussed. PMID:18670607

  18. Studies on vertical transmission of Trichinella spp. in experimentally infected ferrets (Mustela putorius furo), foxes (Vulpes vulpes), pigs, guinea pigs and mice.

    Science.gov (United States)

    Webster, P; Kapel, C M O

    2005-06-30

    Vertical transmission of Trichinella spiralis was evaluated in ferrets (n=21), foxes (n=11), pigs (n=12), guinea pigs (n=16), and mice (n=41). The placental barrier to be crossed by migratory Trichinella larvae varies structurally in different animal species. Ferrets and foxes have an endotheliochorial placenta structure, guinea pigs and mice a haemochorial, and pigs an epitheliochorial placenta. The non-encapsulating Trichinella pseudospiralis larvae have an extended muscle migration prior to entering a muscle cell. To evaluate if T. pseudospiralis was more likely to be transmitted to offspring, an additional group of foxes (n=11) infected with T. pseudospiralis was included. Two different dose levels were used for ferrets, pigs, guinea pigs, and mice. In pigs and guinea pigs, infection was given at different times of the gestation period. Vertical transmission, measured as recovery of muscle larvae in the offspring, was demonstrated in both ferrets groups, in all four guinea pig groups, and in the high dose mouse group, but not in any fox or pig groups. PMID:15925725

  19. First isolation of Aedes flavivirus in the Western Hemisphere and evidence of vertical transmission in the mosquito Aedes (Stegomyia) albopictus (Diptera: Culicidae)

    Energy Technology Data Exchange (ETDEWEB)

    Haddow, Andrew D., E-mail: adhaddow@gmail.com [Institute for Human Infections and Immunity, Center for Emerging Infectious Diseases and Biodefense, Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555-0609 (United States); Guzman, Hilda; Popov, Vsevolod L. [Institute for Human Infections and Immunity, Center for Emerging Infectious Diseases and Biodefense, Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555-0609 (United States); Wood, Thomas G.; Widen, Steven G. [Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555-0609 (United States); Haddow, Alastair D. [Mercy Clinic, 2115 S. Fremont, Springfield, MO 65804 (United States); Tesh, Robert B.; Weaver, Scott C. [Institute for Human Infections and Immunity, Center for Emerging Infectious Diseases and Biodefense, Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555-0609 (United States)

    2013-06-05

    We report here the first evidence of vertical transmission of Aedes flavivirus (AEFV) and its first isolation in the Western Hemisphere. AEFV strain SPFLD-MO-2011-MP6 was isolated in C6/36 cells from a pool of male Aedes albopictus mosquitoes that were reared to adults from larvae collected in southwest Missouri, USA, in 2011. Electron micrographs of the virus showed virions of approximately 45 nm in diameter with morphological characteristics associated with flaviviruses. The genomic sequence demonstrated that AEFV-SPFLD-MO-2011-MP6 shares a high degree of nucleotide and amino acid sequence identity with the AEFV Narita-21 strain, isolated in Japan in 2003. Intracerebral inoculation of newborn mice with the virus failed to produce observable illness or death and the virus did not replicate in vertebrate cells, consistent with a lack of vertebrate host range. - Highlights: ► The first report of Aedes flavivirus (AEFV) in the Western Hemisphere. ► The first evidence of vertical transmission of AEFV in mosquitoes. ► The first electron micrograph of AEFV. ► The first attempt to infect animals with AEFV.

  20. Prevalência de HIV em gestantes e transmissão vertical segundo perfil socioeconômico, Vitória, ES Factores asociados a recidiva en hanseníasis en Mato Grosso, Centro-oeste de Brasil HIV prevalence in pregnant women and vertical transmission in according to socioeconomic status, Southeastern Brazil

    Directory of Open Access Journals (Sweden)

    Anne Caroline Barbosa Cerqueira Vieira

    2011-08-01

    Full Text Available OBJETIVO: Descrever a prevalência de infecção por HIV em gestantes e a taxa de transmissão vertical, segundo o perfil socioeconômico dos bairros de residência das mães. MÉTODOS: Estudo ecológico exploratório utilizando a base de dados do Sistema de Informação de Agravos de Notificação de gestantes HIV-positivas e aids em crianças notificadas entre 2000 e 2006 em Vitória, ES. Para análise das informações socioeconômicas foi utilizado o Índice de Qualidade Urbana. A prevalência de HIV em gestantes e a taxa de transmissão vertical foram calculadas. A distribuição espacial dos casos foi realizada no programa Terraview 3.2.0. Para verificar a associação entre a qualidade urbana e a prevalência de HIV em gestantes utilizou-se o modelo de regressão de Poisson. RESULTADOS: Um total de 137 gestantes e 14 crianças infectadas por transmissão vertical foi notificado no período. Sete crianças correspondiam a mães HIV-positivas sem notificação de caso no período analisado. A prevalência de infecção em gestantes no período foi de 0,44% e a taxa de transmissão vertical foi de 9,7%. CONCLUSÕES: A prevalência de infecção por HIV em gestantes e a transmissão vertical associam-se à qualidade urbana do bairro de residência, indicando que os bairros com menor qualidade urbana devem ser priorizados quanto às ações para redução da transmissão vertical.OBJETIVO: Analizar factores asociados a la ocurrencia de recidiva en hanseníasis. MÉTODOS: Estudio retrospectivo caso-control con 159 pacientes mayores de 15 años diagnosticados con hanseníasis en cinco municipios del Estado de Mato Grosso, Centro-oeste de Brasil, cuyas unidades de salud eran consideradas de referencia para el atendimiento. El grupo de casos incluyó 53 individuos con recidiva de 2005 a 2007 y fue comparado con el grupo control (106 con alta por cura en 2005, pareados por sexo y clasificación operacional. Se usaron datos del Sistema de Informaci

  1. Vertical transmission efficiency and insecticidal properties of Spodoptera exigua Nucleopolyhedrovirus (SeMNPV) genotypes for their use in biological control

    OpenAIRE

    Martínez del Pino, Lara

    2011-01-01

    El nucleopoliedrovirus de Spodoptera exigua (SeMNPV) es un patógeno natural de las poblaciones larvarias de S. exigua que constituye la base de un bioinsecticida comercializado en España para el control biológico de esta plaga en pimiento. Recientes estudios han demostrado que la transmisión del virus a la descendencia (transmisión vertical) se da con frecuencia y podría ser una característica deseable para su uso en aplicaciones de campo. En el presente trabajo se discute la conveniencia de ...

  2. Evidence for natural vertical transmission of chikungunya viruses in field populations of Aedes aegypti in Delhi and Haryana states in India-a preliminary report.

    Science.gov (United States)

    Jain, Jaspreet; Kushwah, Raja Babu S; Singh, Shashi S; Sharma, Anil; Adak, Tridibes; Singh, Om P; Bhatnagar, Raj Kamal; Subbarao, Sarala K; Sunil, Sujatha

    2016-10-01

    Aedes aegypti and Aedes albopictus are principal vectors for the transmission of chikungunya virus (CHIKV). India is a hub for both dengue and chikungunya infections and there are several reports of co-infection of dengue and chikungunya virus in the clinical scenario. The present pilot entomological survey was conducted to evaluate vertical transmission of CHIKV in Aedes field populations. Aedes immature (larvae and pupae) collection was done in 2012, over a period of six months from selected sites in Delhi and Haryana, India. The immatures collected were reared for adult emergence and species identification was done. A. aegypti male and female mosquitoes were separated and pooled collection spot-wise, RNA extracted and RT PCR performed to test for the presence of CHIKV in the pools. Container index (CI) and minimum infection rate (MIR) were estimated. From study areas that tested positive for CHIKV, adult collections were made and females upon feeding on uninfected blood in laboratory were allowed to lay eggs. The progeny that emerged from these field-collected mothers were tested for CHIKV presence. Our pilot survey showed the existence of A. aegypti population even during peak summer season in a few foci which eventually helped the mosquitoes to tide over adverse environmental conditions and with the start of rainfall, the population exploded within a short period of time. Immatures collected from field and progeny of adults collected from the field were CHIKV positive demonstrating the presence of vertical transmission of chikungunya virus in field population of A. aegypti. The present study further demonstrates the importance of identifying permanent breeding sites for proper Aedes species control. PMID:27282096

  3. ASACUSA's radio-frequency quadrupole decelerator, open to show the four-rod structure along the centre, which crosses 35 resonator chambers formed by the vertical partitions.

    CERN Multimedia

    Laurent Guiraud

    2000-01-01

    The Radio-Frequency Quadrupole, RFQD, which further decelerates antiprotons ejected from the Antiproton Decelerator (AD). Starting from a momentum of 100 MeV/c (kinetic energy 5.3 MeV), the RFQD delivers very-low-energy antiprotons, adjustable between 10 and 110 keV, to the experiment ASACUSA. In picture _02, the view from the upstream end shows its 4-rod structure, traversing 35 resonator chambers formed by the vertical partitions. The tank has an inner diameter of 390 mm and is pumped to a vacuum of a few E-8 Torr.

  4. Evidence for Vertical Transmission of Bacterial Symbionts from Adult to Embryo in the Caribbean Sponge Svenzea zeai

    KAUST Repository

    Lee, O. O.

    2009-07-31

    The Caribbean reef sponge Svenzea zeai was previously found to contain substantial quantities of unicellular photosynthetic and autotrophic microbes in its tissues, but the identities of these symbionts and their method of transfer from adult to progeny are largely unknown. In this study, both a 16S rRNA gene-based fingerprinting technique (denaturing gradient gel electrophoresis [DGGE]) and clone library analysis were applied to compare the bacterial communities associated with adults and embryos of S. zeai to test the hypothesis of vertical transfer across generations. In addition, the same techniques were applied to the bacterial community from the seawater adjacent to adult sponges to test the hypothesis that water column bacteria could be transferred horizontally as sponge symbionts. Results of both DGGE and clone library analysis support the vertical transfer hypothesis in that the bacterial communities associated with sponge adults and embryos were highly similar to each other but completely different from those in the surrounding seawater. Sequencing of prominent DGGE bands and of clones from the libraries revealed that the bacterial communities associated with the sponge, whether adult or embryo, consisted of a large proportion of bacteria in the phyla Chloroflexi and Acidobacteria, while most of the sequences recovered from the community in the adjacent water column belonged to the class Alphaproteobacteria. Altogether, 21 monophyletic sequence clusters, comprising sequences from both sponge adults and embryos but not from the seawater, were identified. More than half of the sponge-derived sequences fell into these clusters. Comparison of sequences recovered in this study with those deposited in GenBank revealed that more than 75% of S. zeai-derived sequences were closely related to sequences derived from other sponge species, but none of the sequences recovered from the seawater column overlapped with those from adults or embryos of S. zeai. In

  5. Transmissão vertical do HIV em Fortaleza: revelando a situação epidemiológica em uma capital do nordeste

    Directory of Open Access Journals (Sweden)

    Cavalcante Maria do Socorro

    2004-01-01

    Full Text Available OBJETIVO: analisar as condutas que visam a redução da transmissão vertical do HIV nas grávidas infectadas atendidas nas maternidades públicas de Fortaleza. MÉTODOS: estudo descritivo no qual os bancos de dados do SINASC, SINAN e LACEN foram cruzados, procurando-se identificar as grávidas infectadas pelo HIV, seguido de busca ativa das informações complementares em prontuários médicos nas maternidades públicas. RESULTADOS: foram identificadas 138 grávidas infectadas pelo HIV. Observou-se que 35,5% destas já conheciam o status sorológico antes da gravidez e 48,6% foram diagnosticadas durante a gravidez. Das 101 grávidas que se souberam infectadas antes ou durante a gravidez, apenas 47,5% utilizaram, de forma correta, todas as etapas da profilaxia, incluindo as condutas para o recém-nascido. Associação estatisticamente significante foi encontrada entre o conhecimento prévio da sorologia para o HIV e realização de todas as etapas adequadas de profilaxia (p<0,001. CONCLUSÕES: encontrou-se elevado número de mulheres que não tiveram acesso às diferentes estratégias para redução da transmissão vertical, especialmente entre aquelas que engravidaram sem conhecimento de seu status sorológico. Faz-se necessária a contínua sensibilização e capacitação de todos os profissionais de saúde envolvidos com a assistência às mulheres, em geral, e às grávidas em especial, tendo em vista a aplicação correta das condutas para a redução da transmissão vertical do HIV.

  6. More than just trash bins? Potential roles for extracellular vesicles in the vertical and horizontal transmission of yeast prions.

    Science.gov (United States)

    Kabani, Mehdi; Melki, Ronald

    2016-05-01

    In the yeast Saccharomyces cerevisiae, an ensemble of structurally and functionally diverse cytoplasmic proteins has the ability to form self-perpetuating protein aggregates (e.g. prions) which are the vectors of heritable non-Mendelian phenotypic traits. Whether harboring these prions is deleterious-akin to mammalian degenerative disorders-or beneficial-as epigenetic modifiers of gene expression-for yeasts has been intensely debated and strong arguments were made in support of both views. We recently reported that the yeast prion protein Sup35p is exported via extracellular vesicles (EV), both in its soluble and aggregated infectious states. Herein, we discuss the possible implications of this observation and propose several hypotheses regarding the roles of EV in both vertical and horizontal propagation of 'good' and 'bad' yeast prions. PMID:26553335

  7. Vertical transmission of bovine viral diarrhoea virus (BVDV) in mousedeer (Tragulus javanicus) and spread to domestic cattle

    DEFF Research Database (Denmark)

    Uttenthal, Åse; Høyer, M.J.; Grøndahl, C.;

    2006-01-01

    This study investigates the transmission of bovine viral diarrhoea virus (BVDV) 1f from a persistently infected (PI) lesser Malayan mousedeer to two bovine calves. Different contact routes to two calves were analysed: 1) aerosol contact between two adjacent pens without physical contact; 2......) indirect contact by use of common utensils; 3) direct nose-to-nose contact for 30 seconds. One of the calves was infected either by aerosol or indirect contact. The virus sequence in 247 nucleotides in the 5'-UTR was 100% identical in mousedeer and calf. To elucidate the distribution of BVDV within the...... mousedeer BVD virus in the E2 region (420 nucleotides) through 4 generations showed only 7 mutations, which were maintained from mother to offspring....

  8. A qualitative investigation into knowledge, beliefs, and practices surrounding mastitis in sub-Saharan Africa: what implications for vertical transmission of HIV?

    Directory of Open Access Journals (Sweden)

    Hofmann Jennifer

    2007-02-01

    Full Text Available Abstract Background Mastitis constitutes an important risk factor in HIV vertical transmission. Very little, however, is known on how women in sub-Saharan Africa conceptualise health problems related to breastfeeding, such as mastitis, and how they act when sick. We aimed at filling this gap in knowledge, by documenting the indigenous nosography of mastitis, health seeking behaviour, and remedies for prophylaxis and treatment in rural sub-Saharan Africa. Methods The study was conducted in the Nouna Health District, rural Burkina Faso. We employed a combination of in-depth individual interviews and focus group discussions reaching both women and guérisseuers. All material was transcribed, translated, and analysed inductively, applying data and analyst triangulation. Results Respondents perceived breast problems related to lactation to be highly prevalent and described a sequence of symptoms which resembles the biomedical understanding of pathologies related to breastfeeding, ranging from breast engorgement (stasis to inflammation (mastitis and infection (breast abscess. The aetiology of disease, however, differed from biomedical notions as both women and guerisseurs distinguished between "natural" and "unnatural" causes of health problems related to breastfeeding. To prevent and treat such pathologies, women used a combination of traditional and biomedical therapies, depending on the perceived cause of illness. In general, however, a marked preference for traditional systems of care was observed. Conclusion Health problems related to breastfeeding are perceived to be very common in rural Burkina Faso. Further epidemiological research to assess the actual prevalence of such pathologies is urgently needed to inform the design of adequate control measures, especially given the impact of mastitis on HIV vertical transmission. Our investigation into local illness concepts and health care seeking behaviour is useful to ensure that such measures be

  9. The first evidence for vertical transmission of [i]Babesia canis[/i] in a litter of Central Asian Shepherd dogs

    Directory of Open Access Journals (Sweden)

    Ewa J Mierzejewska

    2014-09-01

    Full Text Available [b]Introduction and objective[/b]. Tick-borne infections constitute an increasing health problem in dogs and may lead to death, especially in young or elderly individuals. Canine babesiosis constitutes a serious health problem in dogs worldwide. The aim of the study was to verify the probability of vertical transmission of [i]Babesia canis[/i] between the bitch and the pups. [b]Materials and methods[/b]. In Autumn 2011, cases of babesiosis were diagnosed in a litter of 6-week-old puppies of a Central Asian Shepherd dog. Immediately following the first case of infection, blood samples were collected from all the pups in the litter (n=10 and from the female. Detection of Babesia infection was performed by molecular and microscopical techniques. [b]Results.[/b] The presence of[i] B. canis [/i]DNA was detected using PCR in three pups, presenting at the time or 24–48 hours later with babesiosis symptoms, and in their asymptomatic mother. The isolates derived from the pups and the female – 520 bp 18S rRNA gene fragment – were compared and analyzed. All isolates from the pups and their mother were identical and showed 100% homology with [i]B. canis[/i] group B (EU622793, supporting the same source of infection. Additionally, the USG of the peritoneal cavity was performed in the female, presenting evidence for splenomegaly. [b]Conclusions.[/b] On the basis of (1 the same timing of three pup cases; (2 the identical [i]B. canis[/i] sequences derived from all positive dogs; (3 evident splenomegaly in the asymptomatic female, this provides the first evidence of the vertical transmission of this piroplasm in dogs.

  10. A comprehensive review of the barriers and promoters health workers experience in delivering prevention of vertical transmission of HIV services in sub-Saharan Africa.

    Science.gov (United States)

    Schuster, Roseanne C; McMahon, Devon E; Young, Sera L

    2016-06-01

    Despite significant biomedical and policy advances, 199,000 infants and young children in sub-Saharan Africa (SSA) became infected with HIV in 2013, indicating challenges to implementation of these advances. To understand the nature of these challenges, we sought to (1) characterize the barriers and facilitators that health workers encountered delivering prevention of vertical transmission of HIV (PVT) services in SSA and (2) evaluate the use of theory to guide PVT service delivery. The PubMed and CINAHL databases were searched using keywords barriers, facilitators, HIV, prevention of vertical transmission of HIV, health workers, and their synonyms to identify relevant studies. Barriers and facilitators were coded at ecological levels according to the Determinants of Performance framework. Factors in this framework were then classified as affecting motivation, opportunity, or ability, per the Motivation-Opportunity-Ability (MOA) framework in order to evaluate domains of health worker performance within each ecological level. We found that the most frequently reported challenges occurred within the health facility level and spanned all three MOA domains. Barriers reported in 30% or more of studies from most proximal to distal included those affecting health worker motivation (stress, burnout, depression), patient opportunity (stigma), work opportunity (poor referral systems), health facility opportunity (overburdened workload, lack of supplies), and health facility ability (inadequate PVT training, inconsistent breastfeeding messages). Facilitators were reported in lower frequencies than barriers and tended to be resolutions to challenges (e.g., quality supervision, consistent supplies) or responses to an intervention (e.g., record systems and infrastructure improvements). The majority of studies did not use theory to guide study design or implementation. Interventions addressing health workers' multiple ecological levels of interactions, particularly the health

  11. Failure to demonstrate experimental vertical transmission of the epidemic strain of Chikungunya virus in Aedes albopictus from La Réunion Island, Indian Ocean

    Directory of Open Access Journals (Sweden)

    Marie Vazeille

    2009-07-01

    Full Text Available Aedes albopictus was responsible for transmission in the first outbreak of chikungunya (CHIK on La Réunion Island, Indian Ocean, in 2005-2006. The magnitude of the outbreak on this island, which had been free of arboviral diseases for over 30 years, as well as the efficiency of Ae. albopictus as the main vector, raises questions about the maintenance of the CHIK virus (CHIKV through vertical transmission mechanisms. Few specimens collected from the field as larvae were found to be infected. In this study, Ae. albopictus originating from La Réunion were orally infected with a blood-meal containing 10(8 pfu/mL of the CHIKV epidemic strain (CHIKV 06.21. Eggs from the first and second gonotrophic cycles were collected and raised to the adult stage. The infectious status of the progeny was checked (i by immunofluorescence on head squashes of individual mosquitoes to detect the presence of viral particles or (ii by quantitative RT-PCR on mosquito pools to detect viral RNA. We analysed a total of 1,675 specimens from the first gonotrophic cycle and 1,709 from the second gonotrophic cycle without detecting any viral particles or viral RNA. These laboratory results are compared to field records.

  12. Genetic Variability of Bovine Viral Diarrhea Virus and Evidence for a Possible Genetic Bottleneck during Vertical Transmission in Persistently Infected Cattle.

    Directory of Open Access Journals (Sweden)

    Natalie Dow

    Full Text Available Bovine viral diarrhea virus (BVDV, a Pestivirus in the family Flaviviridae, is an economically important pathogen of cattle worldwide. The primary propagators of the virus are immunotolerant persistently infected (PI cattle, which shed large quantities of virus throughout life. Despite the absence of an acquired immunity against BVDV in these PI cattle there are strong indications of viral variability that are of clinical and epidemiological importance. In this study the variability of E2 and NS5B sequences in multiple body compartments of PI cattle were characterized using clonal sequencing. Phylogenetic analyses revealed that BVDV exists as a quasispecies within PI cattle. Viral variants were clustered by tissue compartment significantly more often than expected by chance alone with the central nervous system appearing to be a particularly important viral reservoir. We also found strong indications for a genetic bottleneck during vertical transmission from PI animals to their offspring. These quasispecies analyses within PI cattle exemplify the role of the PI host in viral propagation and highlight the complex dynamics of BVDV pathogenesis, transmission and evolution.

  13. Systematic review on tuberculosis transmission on aircraft and update of the European Centre for Disease Prevention and Control risk assessment guidelines for tuberculosis transmitted on aircraft (RAGIDA-TB).

    Science.gov (United States)

    Kotila, Saara M; Payne Hallström, Lara; Jansen, Niesje; Helbling, Peter; Abubakar, Ibrahim

    2016-01-01

    As a setting for potential tuberculosis (TB) transmission and contact tracing, aircraft pose specific challenges. Evidence-based guidelines are needed to support the related-risk assessment and contact-tracing efforts. In this study evidence of TB transmission on aircraft was identified to update the Risk Assessment Guidelines for TB Transmitted on Aircraft (RAGIDA-TB) of the European Centre for Disease Prevention and Control (ECDC). Electronic searches were undertaken from Medline (Pubmed), Embase and Cochrane Library until 19 July 2013. Eligible records were identified by a two-stage screening process and data on flight and index case characteristics as well as contact tracing strategies extracted. The systematic literature review retrieved 21 records. Ten of these records were available only after the previous version of the RAGIDA guidelines (2009) and World Health Organization guidelines on TB and air travel (2008) were published. Seven of the 21 records presented some evidence of possible in-flight transmission, but only one record provided substantial evidence of TB transmission on an aircraft. The data indicate that overall risk of TB transmission on aircraft is very low. The updated ECDC guidelines for TB transmission on aircraft have global implications due to inevitable need for international collaboration in contract tracing and risk assessment. PMID:26848520

  14. PREVENTION OF PARENT TO CHILD TRANSMISSION OF HIV : A RETROSPECTIVE STUDY OF 5 YEARS IN A TERTIARY CENTRE , GUNTUR, SOUTH INDIA

    Directory of Open Access Journals (Sweden)

    Potharaju

    2015-02-01

    Full Text Available OBJECTIVE: Mother to child transmission of HIV is a major route of HIV infection in children. The objective of this study is to analyze the response to implementation of PPTCT programme, the response of the spouses of the seropositive antenatal women to undergo HIV testing, mode of delivery and breast feeding practices adopted by the ser o positive postnatal women and the status of infants after delivery at 18 months. METHODS : This retrospective study was done in the Department Of Obstetrics and Gynecology, Guntur Medical College, Guntur, A.P, India and data collected from April 2009 to march 2014, a period of 5 years was studied. PPTCT centre was established in our institution in 2003. The practice in our institution is that all pregnant women attending the Antenatal clinic or Labour Room are counseled for HIV testing, and tested as per NACO guidelines. Babies born to HIV s e ropositive women are followed up to 18 months for confirmatory testing. RESULTS : The number of antenatal women counseled who opted for HIV testing were 99.4% and women who tested seropositive was 1.6 %, 1.3%, 0.9%, 0.84%, 0.6% for the years 2009 - 10, 10 - 11, 11 - 12, 12 - 13, 13 - 14 respectively showing a declining trend in the prevalence of HIV in antenatal women. 94.6% of women attended the post - test counseling . Spouses of ser o positive antenatal women who opted for testing was 52.5% and seropositivity in the spouses tested was 65.87% during the study period. Of the 767 seropositive women who delivered, 542(70.66% had vaginal delivery 225(29.33% had LSCS for obstetric indication. Of the 767 seropositive women who delivered 719(93.7% had live births, 28(3.65% had intrauterine fetal demise and 20(2.6% newborns died in the perinatal period. The number of seropositive women opting for exclusive replacement feeding was 54.4% during the study period April 2009 to March 2014. Confirmatory test for infants was done at 18 months and of the 136 infants tested, 14 were

  15. What is the Reason for Poor Outcome of Antepartum Immunoprophylaxis of Hepatitis B Immunoglobulin in Prevention of Vertical Hepatitis B Transmission?

    Directory of Open Access Journals (Sweden)

    Bita Behnava

    2007-09-01

    reduced the maternal HBV-DNA levels of 56 cases from log10 7.38±1.17 copies/mL to log10 5.28±2.77 copies/mL (P<0.05 (13. While in another study, this regimen could not significantly reduce HBV-DNA levels (11. Xiao et al. (8 did not have HBV-DNA levels in the mothers. Therefore, concluding that hepatitis B had decreased needs more proving data. Furthermore, anti-HBcAb in neonates is an evidence of intrauterine transmission of HBV (14, 15, but in this study it is missing. Passive-active immunoprophylaxis with HBIG and hepatitis B vaccine in the infants of HBV carriers gives high levels of protection against vertical transmission and the rate of infantile infection is uncommon in HBeAg positive and negative mothers (7, 16-19 except in China where rate of transmission is reported to be high (13, 20, 21. Some infants may be infected intrapartumly or postpartumly and not intrauterinely. It was better to evaluate the cases after completion of postnatal immunoprophylaxis or 12 months after birth (22. In Xiao et al. (8 study the rate of vertical transmission with and without HBIG in mothers was significantly more than that in other reports. Is the mean HBV-DNA level in Chinese women higher than that from other parts of the world? Does genotype of hepatitis possibly B affect the HBV-DNA levels and rate of transmission? If the rate of infection after passive-active immunoprophylaxis in infants and passive immunoprophylaxis in mothers at antepartum period had not decreased to near zero percent, we should consider other interventions after evaluation of failure causes. Some studies in highly viremic HBsAg positive mothers have shown that, reduction of viremia by lamivudine therapy in the last month of pregnancy could effectively and safely reduce the rate of vertical transmission (13, 23.

  16. Transmissão Vertical Zero: parceria entre o serviço público e o terceiro setor Transmisión Vertical Cero: sociedad entre el servicio público y el Tercer Sector Project Zero Perinatal HIV Transmission: partnership between public and private agencies

    Directory of Open Access Journals (Sweden)

    Janie Maria de Almeida

    2009-01-01

    Full Text Available OBJETIVOS: Divulgar experiência multidisciplinar de parceria entre gestores da rede pública de saúde e organizações não-governamentais voltadas à atenção à gestante HIV positivo; e caracterizar as situações de exposição ao HIV por gestantes atendidas pelo Projeto Transmissão Vertical Zero do Município de Sorocaba - SP. MÉTODOS: Estudo retrospectivo com emprego de fontes documentais, e com levantamento de dados para caracterização sócio-demográfica e situações de exposição ao risco de infecção pelo HIV de 120 gestantes atendidas pelo Projeto, entre 1998 e 2004. RESULTADOS: O compartilhamento de ações entre o público e o terceiro setor constituiu-se em eficiente alternativa de assistência à mulher soropositiva para o HIV, ainda que 56,7% das gestantes desconhecessem a sorologia do parceiro e 73,3% nunca terem usado preservativo. CONCLUSÃO: A parceria contribuiu para a redução da transmissão vertical do HIV em Sorocaba - SP.OBJETIVOS: Divulgar la experiencia multidisciplinaria de sociedad entre gestores de la red pública de salud y organizaciones no gubernamentales dirigidas a la atención de la gestante VIH positivo; y caracterizar las situaciones de exposición al VIH por gestantes atendidas por el Proyecto Transmisión Vertical Zero del Municipio de Sorocaba - SP. MÉTODOS: Se trata de un estudio retrospectivo realizado con el empleo de fuentes documentales, y con el levantamiento de datos para caracterización socio-demográfica y situaciones de exposición al riesgo de infección por el VIH de 120 gestantes atendidas por el Proyecto, entre 1998 y 2004. RESULTADOS: El compartir acciones entre el público y el tercer sector se constituye en una eficiente alternativa de asistencia a la mujer seropositiva para el VIH, aunque el 56,7% de las gestantes desconociese la serología de la pareja y el 73,3% nunca haya usado preservativo. CONCLUSIÓN: La sociedad contribuyó a la reducción de la transmisión vertical

  17. Information Asymmetry,Vertical Market Characteristics and Price Transmission Asymmetry---An Example of Pork Price Transmission%信息不对称、纵向市场特征与猪肉价格传递非对称性

    Institute of Scientific and Technical Information of China (English)

    郭利京; 韩刚; 胡联; 孔小红

    2014-01-01

    Pork prices can not effectively reflect the information of supply and demand for asymmetric price transmission ,which distorts the resource allocation of the pig industry market and is the main reason of cyclical fluctuations in pork prices .This paper discusses the causes of asymmetry price transmission ,economic entities’asymmetric information and the characteristics of vertical pork markets .The mechanism of asymmetric price transmission is generated the intrinsic existence of information asymmetry .Therefore,expanding the scale of pig farming and reducing associated links are the key to breaking the longitudinally asymmetric information , asymmetry price transmission and promoting the healthy development of the pig industry .%价格传递非对称性使猪肉价格不能有效反映市场供求,扭曲了养猪业市场资源配置,是引起我国猪肉价格周期性大幅度波动的主要原因。以纵向市场结构理论和价格形成机制为基础,对比分析了纵向分离市场结构和一体化市场结构下的猪肉价格、猪肉销售量和纵向产业链整体利润情况。结果表明,信息不对称导致的逆向压价效应,不但扭曲了生猪市场价格、降低生猪养殖者利润,也误导了生猪养殖行为;数量众多的生猪散养户、可维持信息不对称和过多纵向关联环节是导致猪肉价格传递非对称的内在原因。因此,扩大生猪养殖规模和减少纵向关联环节数量是打破信息不对称、价格传递非对称性和促进养猪业健康发展的根本措施。

  18. Molecular identification of the first local dengue fever outbreak in Shenzhen city, China: a potential imported vertical transmission from Southeast Asia?

    Science.gov (United States)

    Yang, F; Guo, G Z; Chen, J Q; Ma, H W; Liu, T; Huang, D N; Yao, C H; Zhang, R L; Xue, C F; Zhang, L

    2014-02-01

    A suspected dengue fever outbreak occurred in 2010 at a solitary construction site in Shenzhen city, China. To investigate this epidemic, we used serological, molecular biological, and bioinformatics techniques. Of nine serum samples from suspected patients, we detected seven positive for dengue virus (DENV) antibodies, eight for DENV-1 RNA, and three containing live viruses. The isolated virus, SZ1029 strain, was sequenced and confirmed as DENV-1, showing the highest E-gene homology to D1/Malaysia/36000/05 and SG(EHI)DED142808 strains recently reported in Southeast Asia. Further phylogenetic tree analysis confirmed their close relationship. At the epidemic site, we also detected 14 asymptomatic co-workers (out of 291) positive for DENV antibody, and DENV-1-positive mosquitoes. Thus, we concluded that DENV-1 caused the first local dengue fever outbreak in Shenzhen. Because no imported case was identified, the molecular fingerprints of the SZ1029 strain suggest this outbreak may be due to vertical transmission imported from Southeast Asia. PMID:23587429

  19. Babesiosis due to the canine Babesia microti-like small piroplasm in dogs - first report from Portugal and possible vertical transmission

    Directory of Open Access Journals (Sweden)

    Araújo Manuela

    2011-04-01

    Full Text Available Abstract Background Canine babesiosis (or piroplasmosis is endemic in northern Portugal, but molecularly confirmed cases of infection with small piroplasms have not been reported in the country. Three German shepherd dogs - a bitch and its 2-month old pup and an unrelated male - clinically suspected of piroplasmosis were assessed for babesial infection. Results Parasitemia with small piroplasms was detected by microscopy in two dogs. All three dogs were positive by PCR and the Babesia microti-like small piroplasm (syn. Theileria annae was identified by DNA sequencing. These are the first confirmed cases of babesiosis caused by the B. microti-like piroplasm both in dogs from Portugal and in dogs suspected of clinical piroplasmosis outside of Spain. Conclusions Although the bitch and the male had visited neighboring Galicia (northwestern Spain, where the disease is endemic, incursion of this piroplasm into northern Portugal is evident and infection of the non-traveled pup was due to either vertical transmission or autochthonous tick infection.

  20. Update on System Coordination Centre

    International Nuclear Information System (INIS)

    The new System Coordination Centre at the Power Pool of Alberta was designed to meet the unique requirements of Alberta's electric industry under the new regulatory regime. Development of the Centre, key provisions of the energy management system (EMS) are highlighted. The centre will provide an energy management system for the Pool's system controller function and interface with the Power Pool Administrator's market functions and the operations of the Transmission Administrator. System controllers are expected to be operating from the new location by the end of 1998. Unique EMS features of the centre include: (1) real-time management of energy market and network operations using diverse SCADA/EMS, (2) inter-control centre protocol used to accommodate the unique participant information requirements, and (3) special custom applications. The Centre is expected to be fully functioning by July 1999. 1 fig

  1. Update on System Coordination Centre

    Energy Technology Data Exchange (ETDEWEB)

    Stangl, W. [Power Pool of Alberta, Calgary, AB (Canada)

    1998-07-01

    The new System Coordination Centre at the Power Pool of Alberta was designed to meet the unique requirements of Alberta`s electric industry under the new regulatory regime. Development of the Centre, key provisions of the energy management system (EMS) are highlighted. The centre will provide an energy management system for the Pool`s system controller function and interface with the Power Pool Administrator`s market functions and the operations of the Transmission Administrator. System controllers are expected to be operating from the new location by the end of 1998. Unique EMS features of the centre include: (1) real-time management of energy market and network operations using diverse SCADA/EMS, (2) inter-control centre protocol used to accommodate the unique participant information requirements, and (3) special custom applications. The Centre is expected to be fully functioning by July 1999. 1 fig.

  2. Effects of postnatal interventions for the reduction of vertical HIV transmission on infant growth and non-HIV infections: a systematic review

    Directory of Open Access Journals (Sweden)

    Moleen Zunza

    2013-12-01

    Full Text Available Introduction: Guidelines in resource-poor settings have progressively included interventions to reduce postnatal HIV transmission through breast milk. In addition to HIV-free survival, infant growth and non-HIV infections should be considered. Determining the effect of these interventions on infant growth and non-HIV infections will inform healthcare decisions about feeding HIV-exposed infants. We synthesize findings from studies comparing breast to formula feeding, early weaning to standard-duration breastfeeding, breastfeeding with extended antiretroviral (ARV to short-course ARV prophylaxis, and alternative preparations of infant formula to standard formula in HIV-exposed infants, focusing on infant growth and non-HIV infectious morbidity outcomes. The review objectives were to collate and appraise evidence of interventions to reduce postnatal vertical HIV transmission, and to estimate their effect on growth and non-HIV infections from birth to two years of age among HIV-exposed infants. Methods: We searched PubMed, SCOPUS, and Cochrane CENTRAL Controlled Trials Register. We included randomized trials and prospective cohort studies. Two authors independently extracted data and evaluated risk of bias. Rate ratios and mean differences were used as effect measures for dichotomous and continuous outcomes, respectively. Where pooling was possible, we used fixed-effects meta-analysis to pool results across studies. Quality of evidence was assessed using the GRADE approach. Results and discussion: Prospective cohort studies comparing breast- versus formula-fed HIV-exposed infants found breastfeeding to be protective against diarrhoea in early life [risk ratio (RR=0.31; 95% confidence interval (CI=0.13 to 0.74]. The effect of breastfeeding against diarrhoea [hazard ratio (HR=0.74; 95% CI=0.57 to 0.97] and respiratory infections (HR=0.65; 95% CI=0.41 to 1.00 was significant through two years of age. The only randomized controlled trial (RCT available

  3. Human Immunodeficiency Virus (HIV types Western blot (WB band profiles as potential surrogate markers of HIV disease progression and predictors of vertical transmission in a cohort of infected but antiretroviral therapy naïve pregnant women in Harare, Zimbabwe

    Directory of Open Access Journals (Sweden)

    Chirenje Mike Z

    2011-01-01

    Full Text Available Abstract Background Expensive CD4 count and viral load tests have failed the intended objective of enabling access to HIV therapy in poor resource settings. It is imperative to develop simple, affordable and non-subjective disease monitoring tools to complement clinical staging efforts of inexperienced health personnel currently manning most healthcare centres because of brain drain. Besides accurately predicting HIV infection, sequential appearance of specific bands of WB test offers a window of opportunity to develop a less subjective tool for monitoring disease progression. Methods HIV type characterization was done in a cohort of infected pregnant women at 36 gestational weeks using WB test. Student-t test was used to determine maternal differences in mean full blood counts and viral load of mothers with and those without HIV gag antigen bands. Pearson Chi-square test was used to assess differences in lack of bands appearance with vertical transmission and lymphadenopathy. Results Among the 64 HIV infected pregnant women, 98.4% had pure HIV-1 infection and one woman (1.7% had dual HIV-1/HIV-2 infections. Absence of HIV pol antigen bands was associated with acute infection, p = 0.002. All women with chronic HIV-1 infection had antibody reactivity to both the HIV-1 envelope and polymerase antigens. However, antibody reactivity to gag antigens varied among the women, being 100%, 90%, 70% and 63% for p24, p17, p39 and p55, respectively. Lack of antibody reactivity to gag p39 antigen was associated with disease progression as confirmed by the presence of lymphadenopathy, anemia, higher viral load, p = 0.010, 0.025 and 0.016, respectively. Although not statistically significant, women with p39 band missing were 1.4 times more likely to transmit HIV-1 to their infants. Conclusion Absence of antibody reactivity to pol and gag p39 antigens was associated with acute infection and disease progression, respectively. Apart from its use in HIV disease

  4. Vers une approche individu-centrée pour modéliser et simuler l’expression spatiale d’une maladie transmissible : la peste à Madagascar

    OpenAIRE

    Badariotti, Dominique; Banos, Arnaud; Laperrière, Vincent

    2007-01-01

    Depuis l’introduction de la peste à Madagascar par les colons européens, les recherchessur le cycle épidémiologique du foyer malgache se sont concentrées sur les processus de transmission du bacille pesteux entre les hôtes principaux -les rats- et secondaires -les hommes- via un vecteur, les puces. Ces mécanismes sont désormais bien connus grâce à la démarche expérimentale de laboratoire. L’enjeu actuel des recherches porte davantage sur l’analyse des processus d’émergence, de réémergence, de...

  5. Community voices: barriers and opportunities for programmes to successfully prevent vertical transmission of HIV identified through consultations among people living with HIV

    Directory of Open Access Journals (Sweden)

    Christoforos Mallouris

    2012-07-01

    Full Text Available Introduction: In 2010, two global networks of people living with HIV, the International Community of Women Living with HIV (ICW Global and the Global Network of People living with HIV (GNP +  were invited to review a draft strategic framework for the global scale up of prevention of vertical transmission (PVT through the primary prevention of HIV and the prevention of unintended pregnancies among women living with HIV. In order to ensure recommendations were based on expressed needs of people living with HIV, GNP+ and ICW Global undertook a consultation amongst people living with HIV which highlighted both facilitators and barriers to prevention services. This commentary summarizes the results of that consultation. Discussion: The consultation was comprised of an online consultation (moderated chat-forum with 36 participants from 16 countries, an anonymous online e-survey (601 respondents from 58 countries, and focus-group discussions with people living with HIV in Jamaica (27 participants. The consultation highlighted the discrepancies across regions with respect to access to essential packages of PVT services. However, the consultation participants also identified common barriers to access, including a lack of trustworthy sources of information, service providers’ attitudes, and gender-based violence. In addition, participant responses revealed common facilitators of access, including quality counselling on reproductive choices, male involvement, and decentralized services. Conclusions: The consultation provided some understanding and insight into the participants’ experiences with and recommendations for PVT strategies. Participants agreed that successful, comprehensive PVT programming require greater efforts to both prevent primary HIV infection among young women and girls and, in particular, targeted efforts to ensure that women living with HIV and their partners are supported to avoid unintended pregnancies and to have safe, healthy

  6. 乙肝父婴垂直传播的临床观察%Clinical observation on vertical transmission from HBsAg-positive fathers to infants

    Institute of Scientific and Technical Information of China (English)

    陈起燕; 张荣莲; 黄欣欣; 修晓燕; 任坤海; 王梅颖

    2013-01-01

    Objective: To explore the effect of paternal hepatitis B virus (HBV) infection on infants.Methods: The positive status of serum HBeAg, paternal serum HBV DNA load, paternal spermic HBV DNA load, and neonatal umbilical cord blood HBV DNA were observed among 306 families with HBsAg - positive fathers, serum negative - HBVM and negative - HBVDNA mothers.Results: The incidence rates of paternal liver dysfunction was 7.5% ; the incidence rate of HBV infection among neonates was 21.6% (66/306) ; in case group, 81.8% of fathers were found with positive HBeAg, the positive rates of blood HBV DNA and spermic HBV DNA were 100% and 54.2% , respectively, which were 8.7, 2.1, and 34.3 times more than those among HBsAg - negative fathers.Conclusion: Paternal serum HBeAg, HBV DNA, and spermic HBV DNA detections should be included into conventional detection of men with positive HBsAg during antenatal care; necessary, systematic, and effective antiviral therapy among the patients with positive results may play an active and effective role in prevention of vertical transmission from HBsAg - positive fathers to infants.%目的:探讨父亲单方为乙肝病毒(HBV)感染者对子代的影响.方法:对父亲HBsAg阳性,母亲血清HBVM及HBVDNA均为阴性的306个家庭进行父亲血清HBeAg阳性状态、父亲血清HBV-DNA病毒载量、父亲精液HBV-DNA载量及新生儿脐带血HBV-DNA进行临床观察.结果:父亲肝功能异常发生率为7.5%;新生儿HBV感染率为21.6% (66/306);病例组中父亲为HBeAg阳性者达81.8%、血液HBV DNA阳性者达100%、精液HBV DNA阳性者达54.2%,分别是阴性者中发生HBV父婴垂直传播的8.7倍、2.1倍和34.3倍.结论:临床观察结果表明,孕前保健中务必将准父亲的血清HBeAg、HBVDNA、精液HBV DNA列入男性HBsAg阳性者的检测常规,对阳性者进行必要的系统有效的抗病毒治疗将对防范乙肝父婴垂直传播起积极和有效的作用.

  7. HIV positive mothers' beliefs about mother-to-child transmission Creencias de las madres seropositivas respecto a la transmisión vertical del HIV Crenças das mães soropositivas ao HIV acerca da transmissão vertical da doença

    Directory of Open Access Journals (Sweden)

    Lis Aparecida de Souza Neves

    2006-10-01

    Full Text Available Beliefs can influence health behavior. This qualitative study aimed to understand the beliefs that influence HIV positive mothers' behaviors towards prevention methods against mother-to-child transmission. Fourteen women were interviewed. Our research was based on the theoretical Health Belief Model, formed by the following dimensions: perceived susceptibility, perceived severity, perceived benefits and perceived obstacles. Data analysis showed reflections that evidence the paradox in the AIDS epidemic: knowledge does not change behavior; gender relations; fear of death; fear of stigma; financial problems; disbelief in the virus' existence. Identifying beliefs and understanding how to influence the conduction of the health problem can help services to promote patients' adherence.Las creencias son capaces de influenciar el comportamiento del hombre. El objetivo de este estudio cualitativo fue comprender las creencias que influencian el comportamiento de las madres HIV respecto a las medidas profilácticas de la transmisión vertical. Fueron entrevistadas 14 mujeres portadoras de HIV. Los datos fueron analizados utilizando como referencial teórico el Modelo de Creencias de la Salud, que es compuesto por las dimensiones de susceptibilidad percibida, severidad percibida, beneficios percibidos y barreras percibidas. Fueron observadas las contradicciones de la epidemia de SIDA: el conocimiento no muda comportamiento; miedo de la muerte; subestimación del HIV; dificultades financieras; no creer en la existencia del virus. Identificar y comprender las creencias puede ayudar los servicios de salud a promover la adhesión de la clientela.As crenças parecem influenciar diretamente nas atitudes dos seres humanos. Neste estudo qualitativo buscamos identificar as crenças que influenciam a adesão das mães portadoras do HIV às medidas profiláticas da transmissão vertical. Foram entrevistadas 14 mães soropositivas. A análise foi feita utilizando

  8. Vertical Integration, Monopoly, and the First Amendment.

    Science.gov (United States)

    Brennan, Timothy J.

    This paper addresses the relationship between the First Amendment, monopoly of transmission media, and vertical integration of transmission and content provision. A survey of some of the incentives a profit-maximizing transmission monopolist may have with respect to content is followed by a discussion of how vertical integration affects those…

  9. What is the Reason for Poor Outcome of Antepartum Immunoprophylaxis of Hepatitis B Immunoglobulin in Prevention of Vertical Hepatitis B Transmission?

    OpenAIRE

    Bita Behnava; Seyed Moayed Alavian

    2007-01-01

    Hepatitis B virus (HBV) infection is a serious global health problem, with 2 billion people infected worldwide, and 350 million suffering from chronic HBV infection. Hepatitis B infection is the 10th leading cause of death worldwide, and results in 500,000 to 1.2 million deaths per year caused by chronic hepatitis, cirrhosis, and hepatocellular carcinoma (HCC). HCC accounts for 320000 deaths per year (1). The risk of perinatal HBV transmission is greater for infants born from women who are po...

  10. The relativistic two-centre continuum

    International Nuclear Information System (INIS)

    A method is presented to define unique continuum states for the two-centre Dirac Hamiltonian. In the spherical limit these states become the familiar angular momentum eigenstates of the radial Coulomb potential. The different states for a fixed total energy vertical strokeEvertical stroke > m may be distinguished by considering the asymptotic spin-angular distribution of states with unique scattering-phases. First numerical solutions of the two-centre Dirac equation for continuum states are presented. (orig.)

  11. Detection of Torque teno midi virus/Small anellovirus (TTMDV/SAV) in the sera of domestic village chickens and its vertical transmission from hen to eggs.

    Science.gov (United States)

    Bouzari, M; Salmanizadeh, Sh

    2015-01-01

    Although the infection of different animals and non-human primates with other members of Anelloviridae have already been reported there is no report about infection of animals with Torque teno midi virus/Small anellovirs (TTMDV/SAV). The aim of this study was to detect the virus in domestic village chickens. Blood samples were collected from 79 domestic village chickens in Isfahan. Blood samples of five adult laying hens and one cockerel were collected in three consecutive weeks (days 1, 8 and 14) as experimental chickens. Ten eggs were randomly collected from the eggs laid during days 12 to 17 and thin and thick egg whites and yolk samples were collected aseptically. After DNA extraction Nested-PCR was performed using SMAs/SMAr primers. In PCR, 431 bp and 441 bp products were detected. The detected bands were extracted and sequenced. Totally 26 out of 79 (32.9%) of the blood samples were positive for the virus. The frequency of the infection of the different parts of the eggs tested was 76%. For the first time TTMDV/SAV was detected in domestic village chickens which also vertically transmitted to eggs. PMID:27175162

  12. Ongoing Horizontal and Vertical Transmission of Virulence Genes and papA Alleles among Escherichia coli Blood Isolates from Patients with Diverse-Source Bacteremia

    Science.gov (United States)

    Johnson, James R.; O'Bryan, Timothy T.; Kuskowski, Michael; Maslow, Joel N.

    2001-01-01

    The phylogenetic distributions of multiple putative virulence factors (VFs) and papA (P fimbrial structural subunit) alleles among 182 Escherichia coli blood isolates from patients with diverse-source bacteremia were defined. Phylogenetic correspondence among these strains, the E. coli Reference (ECOR) collection, and other collections of extraintestinal pathogenic E. coli (ExPEC) was assessed. Although among the 182 bacteremia isolates phylogenetic group B2 predominated, exhibited the greatest concentration of individual VFs, and contained the largest number of familiar virulent clones, other phylogenetic groups exhibited greater concentrations of certain VFs than did group B2 and included several additional virulent clones. Certain of the newly detected VF genes, e.g., fyuA (yersiniabactin; 76%) and focG (F1C fimbriae; 25%), were as prevalent or more prevalent than their more familiar traditional counterparts, e.g., iut (aerobactin; 57%) and sfaS (S fimbriae; 14%), thus possibly offering additional useful targets for preventive interventions. Considerable diversity of VF profiles was observed at every level within the phylogenetic tree, including even within individual lineages. This suggested that many different pathways can lead to extraintestinal virulence in E. coli and that the evolution of ExPEC, which involves extensive horizontal transmission of VFs and continuous remodeling of pathogenicity-associated islands, is a highly active, ongoing process. PMID:11500406

  13. Study on the risk factors related vertical transmission of HBV positive couples to their infant%父母双方乙型肝炎病毒感染垂直传播的危险因素研究

    Institute of Scientific and Technical Information of China (English)

    张荣莲; 王梅颖; 陈起燕; 修晓燕; 任坤海; 邱丽茵; 黄欣欣

    2012-01-01

    Objective To explore the risk factors and the rate of HBV vertical transmission from HBsAg-positive couple to their infant.Methods 46 families who had antenatal examination at Fujian Provincial Maternal and Child Health Hospital during August 2010 and November 2011 were chosen as research object.Cord blood was sampled after delivery for HBVM and HBV-DNA quantification.Those with HBV-DNA load ≥5 × 102 copies/ml were involved in the case group while those having <5 × 102 copies/ml were chosen as controls.Results The average positive rate of neonatal cord blood HBV-DNA was 45.7% (21/46),while the positive rates of cord blood HBsAg and HBeAg were 34.8%(16/46) and 23.9% (11/46) respectively.The positive rates of maternal serum HBV-DNA and paternal serum HBV-DNA were 52.2% (24/46) and 69.6% (32/46) respectively,with the positive rate of couple serum HBeAg as 39.1% (18/46) and 32.6%(15/46) respectively.Results from univariate analysis showed that hepatitis B surface markers,serum HBeAg-positive,serum HBV-DNA positive,and serum HBV-DNA load of the couples were risk factors to the HBV vertical transmission(x2=8.731,8.414,8.932,9.663,10.823,3.962,13.638,36.501 ;P<0.05).Data from the multivariate analysis showed that maternal serum HBV-DNA positive and paternal serum HBV-DNA load were risk factors to the HBV vertical transmission [OR= 17.6 (1.3-238.4) ;OR = 3.5 (1.6-7.6)].Serum HBV-DNA loads of the couples were positively correlated with the cord blood HBV-DNA load,while the load levels of the couple' s serum HBV-DNA were higher than cord blood HBV-DNA.There appeared dose-response relationship between couple' s serum HBV-DNA load level and the cord blood HBV-DNA load level.Results from the analysis of ROC curve showed that both maternal serum HBV-DNA load level (103 copies/ml) and paternal serum HBV-DNA load level (104 copies/ml) were demarcation points to better forecast the occurrence of vertical transmission of HBV,because there showed higher

  14. Autonomous vertical profiler data management

    Digital Repository Service at National Institute of Oceanography (India)

    Afzulpurkar, S.; Navelkar, G.S.; Desa, E.S.; Madhan, R.; Dabholkar, N.; Prabhudesai, S.P.; Mascarenhas, A.A.M.Q.

    and reduced data �� Ease in operation and one man deployable 2 Fig.1. Autonomous Vertical Profiler Table 1. Autonomous Vertical Profiler Specifications 2. Communication Communication with the AVP is through the satellite modem... Aluminum alloy, Acetal nose & tail cones Propulsion Single DC thruster Electronics 8051 and ARM7 microcontroller based Communication Radio modem (2.4 GHz) & Satellite Transmission (Iridium) GUI Labview based Energy Source Lithium Ion Polymer batteries...

  15. 乙型肝炎病毒父婴垂直传播的危险因素分析%Risk factors for paternal vertical transmission of hepatitis B virus

    Institute of Scientific and Technical Information of China (English)

    张荣莲; 陈起燕; 谢婧娴; 罗颖; 成玲; 郭胜斌; 黄欣欣

    2009-01-01

    临床结局无相关性(P>0.05).结论 父亲血清HBV DNA载量及乙型肝炎一级家族史是HBV父婴垂直传播的危险因素;当父亲HBV DNA载量≥1.0×107 copy/ml时,HBV父婴垂直传播率增加.%Objective To explore the risk factors of and the influence of different hepatitis B virus (HBV) DNA load on paternal vertical transmission of HBV.Methods Totally,161 HBsAg negative women,whose husband was HBsAg positive,attended the antenatal clinics of the Provincial Maternity and Child Health Hospital of Fujian from September 2007 to December 2008 and their newborns were selected,and the epidemiologic information,the duration of being a HBV carrier,the first class HBV family history of the fathers,HBV markers,HBV DNA load,HBsAb of the gravidas,the outcomes of the newborns were all collected.Cord blood was sampled after delivery for HBV DNA quantification and those with HBV DNA load ≥1.0×103 copy/ml were chosen as the case group and those < 1.0×103 copy/ml as control.Results (1) Among the 161 newborns,36 HBV DNA positive cord blood samples were detected,giving a rate of 22.4% (36/161) for paternal vertical transmission of HBV.The HBV DNA positive rate in cord blood was 32.0% (23/72) in HBeAg-positive fathers and 14.6% (13/89) in HBeAg-negative fathers.(2) Univariate analysis showed that HBeAg-positive,HBV DNA positive,first class family history of HBV and the duration of being a HBV carrier of the fathers were risk factors of paternal HBV vertical transmission[X2= 6.892,29.916,29.499 and 23.821,OR = 2.7,5.2,8.3 and 1.4 (P<0.01)].(3) Multivariate analysis found that paternal serum HBV DNA positive and the first class family history of HBV of the father side were risk factors of paternal vertical transmission of HBV (OR = 11.1,95% CI;4.6-27.1;OR = 17.1,95% CI:3.5-82.6).(4) According to the different serum HBV DNA load of the HBsAg-positive father,7 groups were divided.A dose dependent effect was found that the HBV DNA positive rate of the cord blood increased with the rising of

  16. CMS Centre at CERN

    CERN Multimedia

    2007-01-01

    A new "CMS Centre" is being established on the CERN Meyrin site by the CMS collaboration. It will be a focal point for communications, where physicists will work together on data quality monitoring, detector calibration, offline analysis of physics events, and CMS computing operations. Construction of the CMS Centre begins in the historic Proton Synchrotron (PS) control room. The historic Proton Synchrotron (PS) control room, Opened by Niels Bohr in 1960, will be reused by CMS to built its control centre. TThe LHC@FNAL Centre, in operation at Fermilab in the US, will work very closely with the CMS Centre, as well as the CERN Control Centre. (Photo Fermilab)The historic Proton Synchrotron (PS) control room is about to start a new life. Opened by Niels Bohr in 1960, the room will be reused by CMS to built its control centre. When finished, it will resemble the CERN Contro...

  17. 乙型肝炎病毒垂直传播及其预防效果的调查%A Survey on Vertical Transmission of Hepatitis B Virus and the Effect of Prevention

    Institute of Scientific and Technical Information of China (English)

    黄冠; 桂希恩; 黎逢良; 黎剑; 朱木森; 李燕; 刘书

    2013-01-01

    Objective; To estimate vertical transmission of hepatitis B virus (HBV) and the effect of prevention in central China. Methods: Infants whose fathers infected with HBV were received HBV vaccine and were followed at the age of 7-24 months. Infants whose mothers infected with HBV were received both HBIG and HBV vaccine and were followed at the age of 7-24 months. The parents and their children were tested for HBV-marker (HBV-M) and HBV-DNA. Results, None of the children whose father infected with HBV was HBsAg positive (0/117), but 79. 5% (93/ 117) were positive for anti-HBs. Fourteen children whose mothers infected with HBV were HBsAg and HBV-DNA positive (14/491, 2. 9%) and 81. 1% (398/491) were positive for anti-HBs. There was no significant difference of anti-HBs rate between the two groups. Conclusion: This study found no evidence for vertical transmission from father to child. The mother-to-child transmission rate was 2. 9% after passive and active immunization. About 20% of the children were anti-HBs negative after the immunization.%目的:评估乙肝父婴传播及母婴传播情况及阻断效果.方法:以男方HBsAg阳性所生的7-24月龄的婴幼儿为父亲HBsAg阳性组,子女出生后均接种乙肝疫苗;女方HBsAg阳性所生的7-24月龄的婴幼儿为母亲HBsAg阳性组,子女出生后均在24 h内注射乙肝免疫球蛋白并接种乙肝疫苗.分别检测父亲或母亲以及婴幼儿血清的乙肝标志物和HBV-DNA.结果:随访HBsAg阳性父亲及其小孩共117对,没有发现婴幼儿HBsAg阳性者,93名婴幼儿抗-HBs阳性,阳性率为79.5% (93/117);HBsAg阳性母亲及其婴幼儿共491对,14名婴幼儿HB-sAg阳性,母婴传播率2.9%(14/491),398名婴幼儿出现抗-HBs,阳性率为81.1% (398/491).父亲或母亲HB-sAg阳性组之婴幼儿抗-HBs阳性率差异无显著性(x2=0.769,P>0.05).结论:本研究未发现乙型肝炎病毒父婴垂直传播;对新生儿采取主被动免疫方

  18. Vertical microbial transmission in Caribbean bacteriosponges

    OpenAIRE

    Schmitt, Susanne

    2007-01-01

    Bakterienhaltige Schwämme sind durch große Mengen an morphologisch und phylogenetisch unterschiedlichen Mikroorganismen im Mesohyl gekennzeichnet. Diese mikrobiellen Konsortien sind permanent, stabil und hoch-spezifisch mit den Wirts-Schwämmen assoziiert. Über die Entstehung und die Aufrechterhaltung dieser Assoziation ist jedoch wenig bekannt. Es war das erste Ziel dieser Doktorarbeit, Co-Speziation zwischen mediterranen und karibischen Schwämmen der Gattung Aplysina und assoziierten Cyanoba...

  19. CMCC Data Distribution Centre

    Science.gov (United States)

    Aloisio, Giovanni; Fiore, Sandro; Negro, A.

    2010-05-01

    The CMCC Data Distribution Centre (DDC) is the primary entry point (web gateway) to the CMCC. It is a Data Grid Portal providing a ubiquitous and pervasive way to ease data publishing, climate metadata search, datasets discovery, metadata annotation, data access, data aggregation, sub-setting, etc. The grid portal security model includes the use of HTTPS protocol for secure communication with the client (based on X509v3 certificates that must be loaded into the browser) and secure cookies to establish and maintain user sessions. The CMCC DDC is now in a pre-production phase and it is currently used only by internal users (CMCC researchers and climate scientists). The most important component already available in the CMCC DDC is the Search Engine which allows users to perform, through web interfaces, distributed search and discovery activities by introducing one or more of the following search criteria: horizontal extent (which can be specified by interacting with a geographic map), vertical extent, temporal extent, keywords, topics, creation date, etc. By means of this page the user submits the first step of the query process on the metadata DB, then, she can choose one or more datasets retrieving and displaying the complete XML metadata description (from the browser). This way, the second step of the query process is carried out by accessing to a specific XML document of the metadata DB. Finally, through the web interface, the user can access to and download (partially or totally) the data stored on the storage device accessing to OPeNDAP servers and to other available grid storage interfaces. Requests concerning datasets stored in deep storage will be served asynchronously.

  20. Towards the complete eradication of mother-to-child HIV/HBV coinfection at Saint Camille Medical Centre in Burkina Faso, Africa

    Directory of Open Access Journals (Sweden)

    Denise Ilboudo

    2010-06-01

    Full Text Available The coinfection of HIV and hepatitis B virus (HBV and their vertical transmission constitute a public health problem in sub-Saharan countries of Africa. The objectives of this research are: i identify the pregnant women that are coinfected by HIV and HBV at Saint Camille Medical Centre; ii use three antiretroviral drugs (zidovudine, nevirapine and lamivudine to interrupt the vertical transmission of HIV and HBV from infected mothers; and iii use the PCR technique to diagnose children who are vertically infected by these viruses in order to offer them an early medical assistance. At Saint Camille Medical Centre, 115 pregnant women, aged from 19 to 41 years, were diagnosed as HIV-positive and, among them, 14 coinfected with HBV. They had at least 32 weeks of amenorrhoea and all of them received the HAART, which contained lamivudine. Two to six months after childbirth, the babies underwent PCR diagnosis for HIV and HBV. The results revealed that, among these mothers, 64.4% were housewives, 36.5% were illiterates, and only 1.7% had a university degree. The rate of vertical transmission of HIV and HBV was 0.0% (0/115 and 21.4% (3/14, respectively. The 3 mothers who transmitted the HBV to their children had all HBsAg, HbeAg, and HBV DNA positive. An antiretroviral therapy that in addition to zidovudine and nevirapine includes lamivudine could, as in the present study, block or reduce the vertical transmission in HIV positive pregnant women who are coinfected with HBV.

  1. Client Centred Desing

    DEFF Research Database (Denmark)

    Ørngreen, Rikke; Nielsen, Janni; Levinsen, Karin

    2008-01-01

    In this paper we argue for the use of Client Centred preparation phases when designing complex systems. Through Client Centred Design human computer interaction can extend the focus on end-users to alse encompass the client's needs, context and resources.......In this paper we argue for the use of Client Centred preparation phases when designing complex systems. Through Client Centred Design human computer interaction can extend the focus on end-users to alse encompass the client's needs, context and resources....

  2. SAP Nuclear Competence Centre

    International Nuclear Information System (INIS)

    In this issue we continue and introduce the SAP Nuclear Competence Centre and its head Mr. Igor Dzama. SAP Nuclear Competence Centrum is one of the fi rst competence centres outside ENEL headquarters. It should operate in Slovakia and should have competencies within the whole Enel group. We are currently dealing with the issues of organisation and funding. We are trying to balance the accountability to the NPP directors and to the management of the competence centres at Enel headquarters; we are looking at the relations between the competence centres within the group and defining the services that we will provide for the NPPs. author)

  3. Canadian Irradiation Centre

    International Nuclear Information System (INIS)

    The Canadian Irradiation Centre is a non-profit cooperative project between Atomic Energy of Canada Limited, Radiochemical Company and Universite du Quebec, Institut Armand-Frappier, Centre for Applied Research in Food Science. The Centre's objectives are to develop, demonstrate and promote Canada's radiation processing technology and its applications by conducting applied research; training technical, professional and scientific personnel; educating industry and government; demonstrating operational and scientific procedures; developing processing procedures and standards, and performing product and market acceptance trials. This pamphlet outlines the history of radoation technology and the services offered by the Canadian Irradiation Centre

  4. Study on the relationship between semen HBV-DNA load and offspring-paternal-vertical-transmission of HBV%HBV感染者精液HBV-DNA载量对子代垂直传播的影响

    Institute of Scientific and Technical Information of China (English)

    张荣莲; 王梅颖; 陈起燕; 任坤海; 修晓燕; 邱丽茵; 黄艳红

    2014-01-01

    Objective To explore the relationship between HBV-DNA load and the offspring vertical transmission of HBV.Methods 138 families who had taken the examination between August 2009 and November 2011 but the HBsAg of the housewife was negative,were chosen as research objects.Blood from the couples and sperms from the husbands during pregnancy were followed and collected for detection on related indicators.Cord blood was sampled after delivery for HBVM and HBV-DNA quantification.Those with HBV-DNA load ≥5 × 102 copies/ml were chosen as cases while those <5 × 102 copies/ml were formed as controls,respectively.Results 1) The positive rates of HBV-DNA was 34.8% (48/138) in the neonatal cord blood while the positive rates of cord blood HBsAg and HBeAg were 28.3% (39/138) and 15.2% (21/138) respectively.2) The positive rate of semen HBV-DNA was 21.0% (29/138) while the positive rates of paternal serum HBV-DNA and HBeAg were 76.8% (106/138)and 42.8% (59/138).3)Among the positive ones on paternal serum HBV-DNA,paternal serum HBeAg,semen HBV-DNA,items as measures taken for HBV vertical transmission and prevention on the fathers and the first class family histories on HBV appeared to be the risk factors for HBV paternal transmission (P<0.05).4)Data from Multivariate analysis showed that positivities on patemal serum HBV-DNA,paternal serum HBeAg and semen HBV-DNA were risk factors for HBV paternal transmission (OR=5.7,95%CI:1.1-29.1 ; OR=4.2,95%CI:1.7-10.0; OR=6.7,95% CI:2.4-18.9).5)Dose-response relationships were seen between levels of paternal serum HBV-DNA load and cord blood HBV-DNA load,between levels of paternal serum HBV-DNA load and semen HBV-DNA load,between levels of semen HBV-DNA load and cord blood HBV-DNA load.6)Results from the analysis on ROC curve showed that paternal serum HBV-DNA load level (105 copies/ml) and semen HBV-DNA load level (103 copies/ml)were better demarcation points to forecast the occurrence of paternal transmission of

  5. Vertical Farming

    OpenAIRE

    Molina Núñez, Antonio José

    2012-01-01

    El fin de la instalación es producir frutas y verduras utilizando la menor superficie posible en planta, debido a la escasez y encarecimiento de esta, incremento de la población y desertificación. Para ello esta modalidad de plantación, Vertical farming, utiliza el desarrollo en altura, aprovechando la superficie lo máximo posible combinado con una nueva técnica, hidroponia, que es la forma de cultivar las plantas sin tierra. Facultad de Ciencias de la Empresa Universidad...

  6. Resultados de la aplicación de tres guías nacionales para prevenir la transmisión vertical del VIH en el Instituto Nacional Materno Perinatal. Lima, Perú Results of the implementation of three national guidelines for the prevention of HIV vertical transmission in instituto Nacional Materno Perinatal. Lima, Perú

    Directory of Open Access Journals (Sweden)

    Carlos Velásquez

    2011-09-01

    Full Text Available Se realiza un análisis retrospectivo de tres periodos sucesivos entre los años 1996 al 2009, para evaluar el impacto de la aplicación de tres guías nacionales para la prevención de la transmisión vertical del VIH. Se incluyeron 275 nacimientos en los 13 años de estudio. Se encontraron diferencias significativas en el porcentaje de casos de VIH entre los niños expuestos al virus en los tres periodos: 15 % durante el periodo en el cual solo se administraba zidovudina (AZT a la gestante; 6,4 % durante el segundo (administración de AZT a la gestante sin criterios de inicios de TARGA, y TARGA a las que tenían criterios para este tratamiento, y 4 % durante el tercer periodo en el cual se aplicó TARGA a todas las gestantes con infección por VIH. El 95 % de las gestantes culminaron el embarazo por cesárea y el 100 % de niños recibió fórmula maternizada. Los cambios realizados en las guías nacionales han producido un impacto favorable en la disminución de nacimientos de niños infectados por el VIH en el Instituto Nacional Materno Perinatal en Perú.A retrospective analysis is performed in three successive periods between the years 1996 and 2009, in order to evaluate the impact of the implementation of three national guidelines for the prevention of the vertical transmission of HIV. 275 births were included in 13 years. Significant statistical differences were found in the percentage of HIV cases in the children exposed to the virus between the three periods: 15% during the period in which only zidovudine (AZT was administered to the pregnant woman, 6.4% during the second period (administration of AZT to the pregnant woman not fulfilling HAART initiation criteria and HAART to those fulfilling criteria for this treatment, and 4% during the third period in which HAART was applied to all pregnant women with HIV infection. 95% of pregnant women ended their pregnancy by cesarean section and the 100% of children received infant formula

  7. Control of mother-to-child transmission of infectious diseases in Brazil: progress in HIV/AIDS and failure in congenital syphilis Controle da transmissão vertical de doenças infecciosas no Brasil: avanços na infecção pelo HIV/AIDS e descompasso na sífilis congênita

    Directory of Open Access Journals (Sweden)

    Alberto Novaes Ramos Jr.

    2007-01-01

    Full Text Available In Brazil, syphilis and HIV infection are considered serious public health problems. However, in practice, epidemiological surveillance, prevention measures, and prenatal care seem to be more effective in the control of mother-to-child transmission of the HIV than in the control of transmission of the Treponema pallidum. Here we discuss the differences in surveillance, prenatal care, and care of the newborn. Important differences were identified. It is concluded that there is an urgent need to establish prevention of mother-to-child transmission of syphilis as a public health priority, using an integrated approach including women's health, children's health, primary health care, and STD/AIDS programs on all governmental levels. These issues also need to be discussed with all stakeholders involved. Important aspects related to the problem are the training of public health professionals, as well as the participation of the community. The elimination of congenital syphilis does not require expensive drugs, and diagnostic tools, but a long-term sustainable approach.No Brasil, a infecção pelo Treponema pallidum e pelo vírus da imunodeficiência humana são eventos considerados prioritários. No entanto, apesar das políticas públicas, a resposta em termos das ações de vigilância e prevenção, assistência pré-natal e ao recém-nascido, é diferenciada, parecendo ser mais bem estruturada para a redução da transmissão vertical do HIV do que para a do T. pallidum. No presente artigo, potenciais diferenças são analisadas quanto ao desenvolvimento das ações. Identificou-se que as desigualdades existentes na atenção aos dois problemas apresentam dimensões diferenciadas nas regiões do país. Reconheceu-se a necessária e urgente priorização da sífilis na gravidez, envolvendo áreas técnicas como atenção básica, saúde da mulher, saúde da criança e controle de doenças sexualmente transmissíveis, em todas as esferas de governo

  8. Intrauterine vertical transmission of HBV via pathway of peripheral blood mono-nuclear cells%外周血单个核细胞介导的HBV宫内垂直传播

    Institute of Scientific and Technical Information of China (English)

    周娜; 王健

    2014-01-01

    Objective:To study the HBV infection in peripheral blood mononuclear cells in mediating the role of mother -to-child transmission of hepatitis B virus.Methods: The peripheral blood mononuclear cells ( PBMCs ) in maternal and cord blood mononuclear cells ( CBMCs ) in newborns were conventionally isolated by Ficoll-Hypaque medium.The loads of HBV-DNA in peripheral blood of maternal and cord blood of newborns were both detected by PCR .Results:The clinical data showed that the positive detection rates of HBV-DNA in serum and PBMCs of pregnant women with HBeAg (+) were 100.00%( 25/25 ) and 72.00%( 18/25),and the positive detection rates of HBV-DNA in the neonatal umbilical cord blood serum and CBMCs were 60.00%(15/25) and 44.00%(11/25),respectively.There were significantly difference between HBeAg (+) and HBeAg(-) in the pregnant women (P<0.05 ).The positive detection rates of HBV-DNA in neonatal umbilical cord blood serum and CBMCs were higher in the group with high HBV loads (more than 106copies/ml) in PBMCs than those of low HBV loading group (102-103copies/ml).The significantly difference was explored between the two groups.Conclusion: Mononuclear cells can not only be infected by HBV , but also play a critical role in the intrauterine vertical transmission of HBV via the pathway transmitted from PBMCs in pregnant women to CBMCs in newborns.%目的:探讨HBV感染外周血单个核细胞在介导乙肝病毒母婴传播中的作用。方法:以Ficoll-Hypaque常规分离、纯化孕妇外周血单个核细胞( PBMCs )和新生儿脐血单个核细胞( CBMCs ), PCR法检测孕妇外周血和新生儿脐血HBV-DNA。结果:HBeAg(+)孕妇血清和PBMCs内HBV-DNA检出率分别为100.00%(25/25)和72.00%(18/25),其新生儿脐血血清和CBMCs内HBV-DNA检出率分别为60.00%(15/25)和44.00%(11/25),与 HBeAg (-)组相比差异有显著性( P<0.05)。 PBMCs内HBV高复制组其新生儿脐血及CBMCs

  9. HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil Prueba rápida para el HIV como una estrategia para la prevención de la transmisión vertical en Brasil Teste rápido para o HIV como estratégia de prevenção da transmissão vertical no Brasil

    Directory of Open Access Journals (Sweden)

    Valdiléa G Veloso

    2010-10-01

    de Janeiro (4/47 y en seis casos en Porto Alegre (6/79. CONCLUSIONES: La estrategia se mostró factible en las maternidades de Rio de Janeiro y de Porto Alegre. Esfuerzos deben ser emprendidos para maximizar la evaluación durante el trabajo de parto. Fuerte soporte social precisa ser acoplado a esa estrategia para garantizar el acceso de dicha población al sistema de salud posterior a ser dado de alta de la maternidad.OBJETIVO: Analisar a viabilidade da testagem rápida para o HIV entre gestantes na admissão à maternidade e de intervenções para reduzir a transmissão perinatal do HIV. MÉTODOS: Amostra de conveniência de mulheres que desconheciam sua situação sorológica para o HIV quando admitidas para o parto em maternidades públicas do Rio de Janeiro, RJ, e de Porto Alegre, RS, entre março de 2000 e abril de 2002. As mulheres foram aconselhadas e testadas com teste rápido Determine HIV1/2 na maternidade. Infecção pelo HIV foi confirmada pelo algoritmo brasileiro para o diagnóstico da infecção pelo HIV. A transmissão intra-útero foi determinada pelo PCR-DNA-HIV. Foram realizadas análises descritivas dos dados sociodemográficos, número de gestações e de abortos prévios, número de visitas de pré-natal, momento da testagem para o HIV, resultado do teste rápido para o HIV, intervenções recebidas pelos recém-natos e de transmissão vertical do HIV, de acordo com cada cidade. RESULTADOS: A prevalência de HIV entre as mulheres foi 6,5% (N=1.439 em Porto Alegre e 1,3% (N=3.778 no Rio de Janeiro. A maioria foi testada durante o trabalho de parto em Porto Alegre e no pós-parto, no Rio de Janeiro. Cento e quarenta e quatro crianças nasceram de 143 mulheres infectadas pelo HIV. Todos os recém-natos receberam ao menos a profilaxia com zidovudina oral, exceto um em cada cidade. Foi possível evitar qualquer exposição ao leite materno em 96,8% e 51,1% dos recém-natos em Porto Alegre e no Rio de Janeiro, respectivamente. A zidovudina injet

  10. The IGU Knowledge Centre

    NARCIS (Netherlands)

    Huizing, Bernardus

    2005-01-01

    This article describes an innovative service for members of the International Gas Union - IGU. The IGU Knowledge Centre provides members with relevant information and data. In this article is described why, how and where.

  11. Virtual particle therapy centre

    CERN Multimedia

    2015-01-01

    Particle therapy is an advanced technique of cancer radiation therapy, using protons or other ions to target the cancerous mass. This advanced technique requires a multi-disciplinary team working in a specialised centre. 3D animation: Nymus3D

  12. The Bruce Energy Centre

    International Nuclear Information System (INIS)

    The Bruce Energy Centre Development Corporation is a joint venture of the Ontario Energy Corporation and 6 private companies formed to market surplus steam from the Bruce Nuclear Power Development. The corporation will also sell or lease land near Bruce NPD. The Bruce Energy Centre has an energy output of 900 BTU per day per dollar invested. Potential customers include greenhouse operators, aquaculturalists, food and beverage manufacturers, and traditional manufacturers

  13. CENTRE FOR GEOMETRICAL METROLOGY

    DEFF Research Database (Denmark)

    De Chiffre, Leonardo

    The objective of this Annual Report is to give a general introduction to CGM as well as to give an account of the tasks carried out using the facilities of CGM's Instrument Centre during 1998 and 1999.......The objective of this Annual Report is to give a general introduction to CGM as well as to give an account of the tasks carried out using the facilities of CGM's Instrument Centre during 1998 and 1999....

  14. The Aube centre

    International Nuclear Information System (INIS)

    This educational booklet is devoted to a general presentation of the Aube radioactive wastes storage centre. After a short presentation of the Andra, the French national agency for the management of radioactive wastes, it gives some general information about radioactive wastes (origin, classification), containers (quality assurance and different types), wastes transportation (planning, safety), and about the Aube centre itself: description, treatment and conditioning of drums (compacting and injection), storage facilities, geological situation of the site, and environmental controls. (J.S.)

  15. Influencing factors of mother-infant vertical transmission of hepatitis B virus%乙型肝炎病毒母婴传播影响因素探讨

    Institute of Scientific and Technical Information of China (English)

    张薇莉; 赵隽; 李伟

    2011-01-01

    目的 探讨乙型肝炎病毒(HBV)母婴传播的影响因素,寻求降低婴儿HBV感染率的方法.方法 HBV携带及慢性乙型肝炎孕妇共635例,分别比较不同血HBV DNA滴度,不同分娩方式(剖宫产或自然分娩),以及不同肝功能状态孕妇所生婴儿出生时及3月龄时HBV的感染率.新生儿生后12h内肌注乙肝免疫球蛋白200U及重组酵母乙肝疫苗10μg;生后即刻显示血清HBV感染存在者,14d时再肌注乙肝免疫球蛋白200U.结果 孕妇高滴度组(HBV DNA>105拷贝/mL)所生新生儿出生时(14.4%vs4.1%,P<0.01)与3月龄时(4.7% vsO,P<0.01)HBV感染率均高于低滴度组(HBV DNA≤10(5)拷贝/mL).两组新生儿3月龄时HBV感染率均低于出生时(P<0.05).自然分娩的孕妇其婴儿出生时HBV感染率明显高于剖宫产组(P<0.01),但3月龄时,两组感染率接近.HBV携带孕妇所生婴儿出生时HBV感染率明显高于慢性乙型肝炎孕妇所生婴儿(P<0.01),但3月龄时两组婴儿HBV感染率亦接近.结论 孕妇血清HBV DNA水平与新生儿HBV宫内感染密切相关,故降低孕妇血清HBV DNA水平可能成为减少新生儿HBV感染的一种有效途径.在乙肝免疫球蛋白及重组酵母乙肝疫苗的双重保护下,孕妇的分娩方式与肝功能状态对HBV母婴传播无影响.%Objective To study the factors influencing mother-infant vertical transmission of hepatitis B virus (HBV).Methods A total of 635 pregnant women with chronic hepatitis B or chronic asymptomatic HBV carriers were enrolled. The rate of HBV infection was compared between the infants born from the pregnant women of different HBV-DNA load, different ways of delivery and different liver functions at birth and 3 months after birth. The newborn infants were routinely injected with hepatitis B immunoglobulin (200 IU) and hepatitis B vaccine (10 μg) within 12 hrs of birth. The newborns presenting HBV infection within 24 hrs of birth by serum test were re-injected with hepatitis B

  16. AIDS by mother-to-child transmission: survival analysis of cases followed from 1983 to 2002 in different regions of Brazil AIDS por transmissão vertical: análise de sobrevivência dos casos acompanhados entre 1983 e 2002 nas diferentes regiões do Brasil

    Directory of Open Access Journals (Sweden)

    Luiza Harunari Matida

    2007-01-01

    Full Text Available Antiretroviral therapy contributes to decreasing morbidity and mortality, and ultimately to increasing survival. In Brazil, there are regional differences in HIV epidemiology regarding pregnant women and children with HIV/AIDS. This study evaluates survival time after AIDS diagnosis in 914 children infected by mother-to-child transmission, reported between 1983 and 1998 and followed until 2002, in Brazil's five regions. Time between birth and HIV diagnosis decreased over the years, mainly in the South and Southeast Regions. There was a significant improvement in survival; more than 75% of cases were still living four years after diagnosis in the 1997-1998 group. This Brazilian study demonstrates that even with regional inequalities in health care infrastructure it is possible for a developing country to establish an effective system of universal and free access to antiretroviral therapy that produces a significant increase in survival for children with AIDS.A terapia anti-retroviral contribui para a diminuição da morbidade e da mortalidade, com conseqüente aumento da sobrevida. No Brasil, há diferenças regionais relativas à dinâmica da epidemia do HIV e ao seu enfrentamento no grupo das gestantes e das crianças com HIV/AIDS. Este estudo verifica o tempo de sobrevida após o diagnóstico de AIDS em 914 crianças infectadas por transmissão vertical, entre os anos de 1983 e 1998, e acompanhadas até 2002, nas cinco regiões brasileiras. O tempo do nascimento ao diagnóstico de infecção pelo HIV, ao longo dos anos, apresenta uma diminuição, principalmente nos estados das regiões Sul e Sudeste. Houve melhora significativa da sobrevivência, mais de 75% dos casos ainda estavam vivendo quatro anos após o diagnóstico, no grupo de 1997 e 1998. Esta análise brasileira mostra ser possível para um país em desenvolvimento estabelecer um sistema efetivo de acesso gratuito e universal à terapia anti-retroviral, mesmo com dificuldades

  17. Apport de la modélisation individu-centrée spatialement explicite à la compréhension de L'expression d'une maladie transmissible : la peste bubonique à Madagascar

    OpenAIRE

    Laperrière, Vincent

    2009-01-01

    La peste est une maladie qui n'a jamais disparu et réémerge même dans certains pays, dont Madagascar. Les recherches consacrées à sa forme bubonique se sont d'abord concentrées sur l'identification des agents hôtes et vecteurs, rongeurs et puces, impliqués dans le cycle épidémiologique, de leur dépendance à l'égard des facteurs environnementaux et des processus de transmission du bacille. Ces facteurs et mécanismes opérant au niveau individuel sont désormais mieux connus, grâce aux acquis des...

  18. The ideal Atomic Centre

    International Nuclear Information System (INIS)

    The author presents considerations which should prove to be of interest to all those who have to design, to construct and to operate a nuclear research centre. A large number of the ideas presented can also be applied to non-nuclear scientific research centres. In his report the author reviews: various problems with which the constructor is faced: ground-plan, infrastructure, buildings and the large units of scientific equipment in the centre, and those problems facing the director: maintenance, production, supplies, security. The author stresses the relationship which ought to exist between the research workers and the management. With this aim in view he proposes the creation of National School for Administration in Research which would train administrative executives for public or private organisations; they would be specialised in the fields of fundamental or applied research. (author)

  19. Lidar Calibration Centre

    Science.gov (United States)

    Pappalardo, Gelsomina; Freudenthaler, Volker; Nicolae, Doina; Mona, Lucia; Belegante, Livio; D'Amico, Giuseppe

    2016-06-01

    This paper presents the newly established Lidar Calibration Centre, a distributed infrastructure in Europe, whose goal is to offer services for complete characterization and calibration of lidars and ceilometers. Mobile reference lidars, laboratories for testing and characterization of optics and electronics, facilities for inspection and debugging of instruments, as well as for training in good practices are open to users from the scientific community, operational services and private sector. The Lidar Calibration Centre offers support for trans-national access through the EC HORIZON2020 project ACTRIS-2.

  20. International research centre launched

    International Nuclear Information System (INIS)

    Full text: The first scientific research and educational institution to be set up on a completely international basis was officially inaugurated in Trieste on 5 October 1964 by the Director General of IAEA, Dr. Sigvard Eklund, when he opened the first seminar of the International Centre for Theoretical Physics. As evidence of the international nature of the institution he noted that the scientists who would work and teach there during the first year represented sixteen different countries. By the end of 1964, the Centre building was nearing completion and three of the five floors were occupied. A successful symposium had been held on the subject of plasma physics, and a score of professors and fellows were at work, from Bulgaria, Czechoslovakia, Greece, India, Japan, Jordan, the Netherlands, Norway, Pakistan, Poland, the United Kingdom, and the United States. A dozen scientific papers had been issued as preprints. The main purpose of the Centre is to foster the advancement of theoretical physics through training and research; at first the chief subject will be high-energy and elementary particle physics. Plasma physics, low energy physics and solid-state physics will also be dealt with. Special attention is paid to the needs of the developing countries. Of the 25 fellows selected for the academic year 1964-65, more than half are from South America, Africa and Asia. In conjunction with the Research Centre, there is an Advanced School for theoretical Physics to provide graduate training for fellows who need such preparation before they embark upon research. The Centre works under the guidance of a Scientific Council comprising the president, Prof. M. Sandoval-Vallarta (Nuclear Energy Commission of Mexico); Prof. A. Abragam (Saclay, France); Prof. R. Oppenheimer (Institute for Advanced Study, Princeton, USA); Dr. V. Soloviev (Dubna, USSR); Prof V.F. Weiskopf (Director General, CERN) ; Prof Abdus Salam (Imperial College, London) ; Prof. P. Budini (University of Trieste

  1. Efficacité de la prévention de la transmission mère-enfant du Virus de l'Immunodéficience Humaine par le protocole 2010 de l'Organisation Mondiale de la Santé au Centre Médical Saint Camille de Ouagadougou (Burkina Faso)

    Science.gov (United States)

    OuédraogoYugbaré, Solange Odile; Zagré, Nikaise; Koueta, Fla; Dao, Lassina; Kam, Ludovic; Ouattara, Diarra Yé; Simporé, Jacques

    2015-01-01

    L’épidémie du Virus de l'Immunodéficience Humaine en milieu pédiatrique est surtout le résultat de la transmission mère-enfant. Notre étude a pour objectif de décrire l'efficacité de la prévention de la transmission mère-enfant du Virus de l'Immunodéficience Humaine par le protocole OMS 2010 (Option A et trithérapie) au centre médical saint Camille de Ouagadougou. Nous avons mené une étude d'une cohorte d'enfants suivis dans le cadre de la prévention de la transmission mère-enfant du Virus de l'Immunodéficience Humaine au centre médical saint Camille de Ouagadougou sur une période de 2 ans allant du 1er Janvier 2012 au 31 Décembre 2013. Nous avons obtenu l'accord de 4900 femmes enceintes pour le dépistage de l'infection du Virus de l'Immunodéficience Humaine et 238 gestantes ont été diagnostiquées séropositives soit 4,86% de séroprévalence. Les femmes étaient surtout infectées par le Virus de l'Immunodéficience Humaine avec de type I (95,38%)). La majorité était sous trithérapie (74,3%) et (25,7%) sous prophylaxie (option A). Les nouveau-nés (92,5%) ont reçu un traitement antirétroviral à base de névirapine dans les 72 heures après la naissance. L'allaitement sécurisé a été appliquée dans 78% des cas. Le taux global de transmission mère-enfant du VIH était de 3,6% avec 3% de transmission chez les enfants nés de mères sous trithérapie antirétrovirale et 6,3% dans les cas de prophylaxie antirétrovirale. Le facteur de risque de transmission a été le long délai du début d'administration des antirétroviraux chez le nouveau-né. La mortalité infantile à un an était de 3,5%. Cette étude a révélé l'efficacité de l'Option A et conforté celle de la trithérapie, le passage à l'Option B+ serait donc plus bénéfique. PMID:26966499

  2. Vers une approche individu-centrée pour modéliser et simuler l’expression spatiale d’une maladie transmissible : la peste à Madagascar

    Directory of Open Access Journals (Sweden)

    Arnaud Banos

    2007-07-01

    Full Text Available Depuis l’introduction de la peste à Madagascar par les colons européens, les recherches sur le cycle épidémiologique du foyer malgache se sont concentrées sur les processus de transmission du bacille pesteux entre les hôtes principaux -les rats- et secondaires -les hommes-  via un vecteur, les puces. Ces mécanismes sont désormais bien connus grâce à la démarche expérimentale de laboratoire. L’enjeu actuel des recherches porte davantage sur l’analyse des processus d’émergence, de réémergence, de diffusion et de conservation de la peste, ce qui suppose de replacer la maladie dans son environnement, dans l’objectif de mieux la contrôler. L’objet de cet article est de montrer, tout en retraçant l’évolution des recherches entreprises sur la peste à Madagascar, l’intérêt heuristique d’une approche récente de modélisation informatique dérivée de l’intelligence artificielle distribuée et fondée sur le paradigme de la complexité : les multi-agents.

  3. Advanced CANDU control centre

    International Nuclear Information System (INIS)

    The CANDU 9 design is based upon the 900 MWe class Darlington station in Canada, which is among the world leading nuclear power stations for capacity factor with low operation, maintenance and administration costs. The CANDU 9 design provides an advanced control centre with enhanced operations features. The advanced AECL control centre design includes the proven functionality of existing CANDU control centres, those implementable characteristics identified by systematic design combined with a human factors analysis of operations requirements and features needed to improve station operability which are made possible by the application of current technology. The design strategy is to preserve the general main control room operations staff work area as unchanged as possible to facilitate the inclusion of past features and operational experience while incorporating operability improvements. The author will present those features of the advanced CANDU control centre which facilitates improved operability capabilities. As well, aspects of the design process utilized, application of simulation technology and conclusions regarding this design approach will be reviewed

  4. Desacralization of Sokol Centres

    Czech Academy of Sciences Publication Activity Database

    Švácha, Rostislav

    Ljubljana : Založba ZRC, 2015 - (Lavrič, A.; Lazarini, F.; Murovec, B.), s. 277-290 ISBN 978-961-254-873-5. - ( Opera Instituti Artis Historiae) Institutional support: RVO:68378033 Keywords : architecture * Sokol centres Subject RIV: AL - Art, Architecture, Cultural Heritage

  5. ATLAS Visitors Centre

    CERN Multimedia

    claudia Marcelloni

    2009-01-01

    ATLAS Visitors Centre has opened its shiny new doors to the public. Officially launched on Monday February 23rd, 2009, the permanent exhibition at Point 1 was conceived as a tour resource for ATLAS guides, and as a way to preserve the public’s opportunity to get a close-up look at the experiment in action when the cavern is sealed.

  6. The GSO Data Centre

    CERN Document Server

    Paletou, F; Génot, V; Rouillard, A; Petit, P; Palacios, A; Caux, E; Wakelam, V

    2015-01-01

    Hereafter we describe the activities of the $Grand \\, Sud-Ouest$ Data Centre operated for INSU/CNRS by the OMP-IRAP and the Universit\\'e Paul Sabatier (Toulouse), in a collaboration with the OASU-LAB (Bordeaux) and OREME-LUPM (Montpellier).

  7. Academic Drug Discovery Centres

    DEFF Research Database (Denmark)

    Kirkegaard, Henriette Schultz; Valentin, Finn

    2014-01-01

    Academic drug discovery centres (ADDCs) are seen as one of the solutions to fill the innovation gap in early drug discovery, which has proven challenging for previous organisational models. Prior studies of ADDCs have identified the need to analyse them from the angle of their economic...

  8. DGNB certified Healthcare Centres

    DEFF Research Database (Denmark)

    Brunsgaard, Camilla; Larsen, Tine Steen

    2015-01-01

    sustainability and wants a certification. This research investigates the decision‐making and design process (DMaDP) behind four DGNB certified Healthcare Centres (HCC) in Northern Jutland in Denmark. In general, knowledge about the DMaDP is important. However it is important to know what part DGNB plays in an...... the architect, the construction engineer, the plumbing engineer etc. which overlap professional field just like other disciplines. Secondly, the general conception is that DGNB brings in limited new things into the project, but it gives a common notion of sustainability which usually can be discussed...... Healthcare Centres, which was certified as office buildings, however more traditional office buildings might differ en experience with DGNB....

  9. Elderly Care Centre

    Science.gov (United States)

    Wagiman, Aliani; Haja Bava Mohidin, Hazrina; Ismail, Alice Sabrina

    2016-02-01

    The demand for elderly centre has increased tremendously abreast with the world demographic change as the number of senior citizens rose in the 21st century. This has become one of the most crucial problems of today's era. As the world progress into modernity, more and more people are occupied with daily work causing the senior citizens to lose the care that they actually need. This paper seeks to elucidate the best possible design of an elderly care centre with new approach in order to provide the best service for them by analysing their needs and suitable activities that could elevate their quality of life. All these findings will then be incorporated into design solutions so as to enhance the living environment for the elderly especially in Malaysian context.

  10. International Data Centre (IDC)

    International Nuclear Information System (INIS)

    The presentation outlines the International Data Centre (Indc) mission, objective and historical background. The Indc progressive commissioning and organizational plans are presented on charts. The IMS stations providing data to Indc operations and the global communication infrastructure are plotted on world maps. The various types of IMS data are thus listed as seismic, hydroacoustic, infrasound and radionuclide. Finally Indc products and services together with its main achievements are listed

  11. The DESY Grid Centre

    International Nuclear Information System (INIS)

    DESY is one of the world-wide leading centers for research with particle accelerators, synchrotron light and astroparticles. DESY participates in LHC as a Tier-2 center, supports on-going analyzes of HERA data, is a leading partner for ILC, and runs the National Analysis Facility (NAF) for LHC and ILC in the framework of the Helmholtz Alliance, Physics at the Terascale. For the research with synchrotron light major new facilities are operated and built (FLASH, PETRA-III, and XFEL). DESY furthermore acts as Data-Tier1 centre for the Neutrino detector IceCube. Established within the EGI-project DESY operates a grid infrastructure which supports a number of virtual Organizations (VO), incl. ATLAS, CMS, and LHCb. Furthermore, DESY hosts some of HEP and non-HEP VOs, such as the HERA experiments and ILC as well as photon science communities. The support of the new astroparticle physics VOs IceCube and CTA is currently set up. As the global structure of the grid offers huge resources which are perfect for batch-like computing, DESY has set up the National Analysis Facility (NAF) which complements the grid to allow German HEP users for efficient data analysis. The grid infrastructure and the NAF use the same physics data which is distributed via the grid. We call the conjunction of grid and NAF the DESY Grid Centre. In the contribution to CHEP2012 we will in depth discuss the conceptional and operational aspects of our multi-VO and multi-community Grid Centre and present the system setup. We will in particular focus on the interplay of Grid and NAF and present experiences of the operations.

  12. The DESY Grid Centre

    Science.gov (United States)

    Haupt, A.; Gellrich, A.; Kemp, Y.; Leffhalm, K.; Ozerov, D.; Wegner, P.

    2012-12-01

    DESY is one of the world-wide leading centers for research with particle accelerators, synchrotron light and astroparticles. DESY participates in LHC as a Tier-2 center, supports on-going analyzes of HERA data, is a leading partner for ILC, and runs the National Analysis Facility (NAF) for LHC and ILC in the framework of the Helmholtz Alliance, Physics at the Terascale. For the research with synchrotron light major new facilities are operated and built (FLASH, PETRA-III, and XFEL). DESY furthermore acts as Data-Tier1 centre for the Neutrino detector IceCube. Established within the EGI-project DESY operates a grid infrastructure which supports a number of virtual Organizations (VO), incl. ATLAS, CMS, and LHCb. Furthermore, DESY hosts some of HEP and non-HEP VOs, such as the HERA experiments and ILC as well as photon science communities. The support of the new astroparticle physics VOs IceCube and CTA is currently set up. As the global structure of the grid offers huge resources which are perfect for batch-like computing, DESY has set up the National Analysis Facility (NAF) which complements the grid to allow German HEP users for efficient data analysis. The grid infrastructure and the NAF use the same physics data which is distributed via the grid. We call the conjunction of grid and NAF the DESY Grid Centre. In the contribution to CHEP2012 we will in depth discuss the conceptional and operational aspects of our multi-VO and multi-community Grid Centre and present the system setup. We will in particular focus on the interplay of Grid and NAF and present experiences of the operations.

  13. Town Centre Redevelopment Strategies

    DEFF Research Database (Denmark)

    Vagnby, Bo Hellisen

    After many years of urban growth Danish downtowns are facing some important choices. Shall the stake one-sidedly be on the town centres as driving forces for growth and 'city marketing', or do they still have a role to play in a broader socio-economic context? In the paper we look back on eight...... slum clearence and urban renewal. To a certain extent parallels are drawn to international experiences, especially where these are of such a nature that they can be assumed transferred to Danish connctions. Conclusively, the strategies are discussed in the light of the turn of Danish urban planning...

  14. Centre liikekeskuksen digital signage

    OpenAIRE

    Bincl, Suzana

    2015-01-01

    Opinnäytetyöni tarkastelee digital signagen suunnittelussa huomioitavia tekijöitä ja sen arvoa markkinointikanavana. Työ on toteutettu tilaustyönä Lappeenrantalaiselle mainostoimisto Mediakolmiolle. Työ sisältää teoriaosuuden lisäksi sisältösuunnitelman rakenteilla olevalle Centre liikekeskukselle. Tavoitteena oli luoda liikekeskukselle sen brändiä tukeva digital signage konsepti. Työ ei sisällä valmista tuotetta, vaan se toimii ehdotelmana myöhemmin alkavalle tuotanno...

  15. [The primary healthcare centres].

    Science.gov (United States)

    Brambilla, Antonio; Maciocco, Gavino

    2014-04-01

    The central attributes of primary care are: first contact (accessibility), longitudinality (person- focused preventive and curative care overtime), patient-oriented comprehensiveness and coordination (including navigation towards secondary and tertiary care). Besides taking care of the needs of the individuals, primary health care teams are also looking at the community, especially when addressing social determinants of health. The rationale for the benefits for primary care for health has been found in: 1) greater access to needed services; 2) better quality of care; 3) a greater focus on prevention; 4) early management of health problems; 5) organizing and delivering high quality care for chronic non-communicable diseases. This paper describes the role of primary healthcare centres in strengthening community primary services and in reducing health inequalities. Furthemore, the experiences of Regional Health Services from Tuscany and Emilia-Romagna are discussed, with a brief overview of the literature. PMID:24770539

  16. Experiences of Telebased Information Centres

    DEFF Research Database (Denmark)

    Falch, Morten

    1999-01-01

    Tele-based information community centres or just tele-centres have been seen as the killer application to empower local communities in developed and developing countries to meet the challenges of the information society. This paper will present a number of models for introducing such centres and ...... and discuss the different models and national strategies used for setting up tele-based information in relation to the Ghana experience.......Tele-based information community centres or just tele-centres have been seen as the killer application to empower local communities in developed and developing countries to meet the challenges of the information society. This paper will present a number of models for introducing such centres...

  17. Investigation of Vertical Distance between Incisive Papilla and Incisal Edge of Maxillary Central Incisors

    OpenAIRE

    Guldag, M. Ustun; Sentut, Fatih; Buyukkaplan, U. Sebnem

    2008-01-01

    Objectives The aim of the present study was to determine the vertical distance between maxillary central incisors and incisive papilla. Methods The vertical distance between incisal edges of maxillary central incisors and the centre of the incisive papilla was measured by a digital caliper on the stone casts that were obtained from dentate subjects. Results The mean vertical distance between maxillary central incisors and incisive papilla on the stone casts was 6.70±0.81 mm. The vertical dist...

  18. Sagittal plane ground reaction forces, centre of pressure and centre of mass in trotting horses.

    Science.gov (United States)

    Hobbs, Sarah J; Clayton, Hilary M

    2013-12-01

    The aims of this study were to measure ground reaction forces (GRFs) of concurrently loaded limbs and to evaluate spatial relationships between the centre of pressure (COP) and centre of mass (COM) in trotting horses. Kinematic (120Hz) and GRF data were collected at trot from three trials of eight horses using four force plates (960 Hz). Forelimb and hind limb GRFs were measured, COP was calculated from the resultant vertical GRF vector and COM was calculated by summation of weighted segmental COMs. Peak total vertical force (19.3 ± 1.3N/kg at 45.1 ± 2.3% diagonal stance) coincided with zero total longitudinal force (45.1 ± 2.4% stance). Initially, COP position corresponded with the fore or hind hoof of the diagonal that contacted the ground earlier. During diagonal overlap, COP position reflected forelimb contribution to total vertical GRF; it maintained a fairly constant position relative to the base of support through the middle part of stance, then moved cranially in the last third of stance towards the fore hoof, which was always the last hoof to leave the ground. The COM moved forward continuously; its longitudinal velocity decreased with the net braking force in early stance and increased with the net propulsive force in late stance. The COM was caudal to the COP in early stance, coincident at 35.8 ± 4.4% stance and was maximally ahead of the COP at 67.6 ± 4.8% stance. Changes in the spatial relationship between COP and COM affect the moment arms of the forelimb and hind limb vertical GRFs and their effect in generating a pitching torque around the COM. PMID:24138935

  19. From Human-Centred to Human-Context centred Approach

    DEFF Research Database (Denmark)

    Rasmussen, Lauge Baungaard

    The article presents and discusses various human centred design approaches . In addtion it suggests a way to use narrative and numeric simulation methods in a combined approach to meet the challenges of sustainable development with a human-context centred approach....

  20. Surveillance of mother-to-child HIV transmission: socioeconomic and health care coverage indicators Vigilância da transmissão vertical do HIV: indicadores socioeconômicos e de cobertura de atenção à saúde

    Directory of Open Access Journals (Sweden)

    Christovam Barcellos

    2009-12-01

    TODOS: Estudo ecológico tendo como unidade de análise as áreas de abrangência de unidades básicas de saúde em Porto Alegre, RS, em 2003. Foram utilizados Sistema de Informações Geográficas e ferramentas de análise espacial para calcular indicadores de cobertura da atenção básica à saúde, condições socioeconômicas e prevalência de nascidos vivos expostos ao HIV durante a gravidez e perinatal. Os dados analisados foram obtidos em sistemas de informação nacionais. A associação entre os diferentes indicadores foi avaliada por meio de teste não-paramétrico de Spearman. RESULTADOS: Observou-se associação entre infecção pelo HIV em gestantes com taxas de natalidade (r=0,22, p<0,01 e falta de assistência pré-natal (r=0,15, p<0,05. As maiores taxas de infecção por HIV em gestantes foram verificadas em áreas com piores condições socioeconômicas e dificuldades de acesso a serviços de saúde (r=0,28, p<0,01. No entanto, a relação observada entre a maior freqüência de assistência pré-natal entre gestantes HIV positivas e maior cobertura vacinal nas áreas (r=0,35, p<0,01 indica a capacidade de detecção precoce da infecção pelo HIV em áreas com melhores serviços de atenção básica. CONCLUSÕES: A pobreza urbana representa um forte condicionante da transmissão vertical do HIV mas a atuação de serviços de vigilância em saúde articulados com a atenção básica podem vencer essa tendência.

  1. Transmission issues

    International Nuclear Information System (INIS)

    This session on transmission issues focused on the role that transmission plays in electricity markets and the importance of getting the market structure right in terms of generation divestiture with buy back contracts, demand side responsive programs, transmission upgrades and long term contracts. The difficulties of distinguishing between market power and scarcity were examined along with some of the complications that ensue if transmission experiences congestion, as exemplified by the August 2003 blackout in eastern North America. The presentations described the best ways to handle transmission issues, and debated whether transmission should be deregulated or follow market forces. Issues of interconnections and reliability of connections were also debated along with the attempt to integrate renewables into the grid. Some presentations identified what new transmission must be built and what must be done to ensure that transmission gets built. The challenges and business opportunities for transmission in Alberta were discussed with reference to plans to invest in new infrastructure, where it is going outside of the province and how it works with other jurisdictions. Manitoba's Conawapa Hydro Project and its 2000 MW tie line to Ontario was also discussed. Some examples of non-optimal use of interconnections in Europe were also discussed in an effort to learn from these mistakes and avoid them in Canada. tabs., figs

  2. Energy Centre Bratislava

    International Nuclear Information System (INIS)

    Energy Centre Bratislava (ECB) is a non-governmental, not-for-profit organization initiating and promoting development and exploitation of energy efficient processes and technologies, use of alternative and renewable energy sources and reduction of energy use impact on environment. ECB was founded in 1993 by European Commission and Upper Austrian Energy Saving Association in the frame of THERMIE program. or the eleven years of the ECB existence, it maintains a rapid growth rate through expansion of its client base and development of its activities. It is one of the few independent institutions working in energy sector of Slovakia. Due in part to these facts and the number of its activities, the ECB has become a generally recognized partner and has achieved an outstanding reputation. It has given advice to governments, institutions, organizations and the European Commission on the formulation of energy policies and the development and implementation of energy plans at a regional, national and European Union level. The principal goal of ECB activities is the promotion and support measures and activities aimed at increasing energy efficiency and improving environmental protection in Slovakia. The objective of the ECB is likewise to contribute to increasing of public energy awareness. ECB plays an active part in transferring innovative technologies and supporting the implementation of concrete projects,activities and legislative changes. The methods used to fulfill this goal include activities in some fields are reviewed. Main previous and current projects of ECB are presented

  3. Thailand's nuclear research centre

    International Nuclear Information System (INIS)

    The Office of Atomic Energy for Peace, Thailand, is charged with three main tasks, namely, Nuclear Energy development Plan, Utilization of Nuclear Based technology Plan and Science and Technology Plan. Its activities are centred around the research reactor TRR-1/M1. The main areas of contribution include improvement in agricultural production, nuclear medicine and nuclear oncology, health care and nutrition, increasing industrial productivity and efficiency and, development of cadre competent in nuclear science and technology. The office also has the responsibility of ensuring nuclear safety, radiation safety and nuclear waste management. The office has started a new project in 1997 under which a 10 MWt research reactor, an isotope production facility and a waste processing and storage facility would be set up by General Atomic of USA. OAEP has a strong linkage with the IAEA and has been an active participant in RCA programmes. In the future OAEP will enhance its present capabilities in the use of radioisotopes and radiation and look into the possibility of using nuclear energy as an alternative energy resource. (author)

  4. CANDU 9 Control Centre Mockup

    International Nuclear Information System (INIS)

    This paper provides a summary of the design process being followed, the benefits of applying a systematic design using human factors engineering, presents an overview of the CANDU 9 control centre mockup facility, illustrates the control centre mockup with photographs of the 3D CADD model and the full scale mockup, and provides an update on the current status of the project. (author)

  5. Council celebrates CERN Control Centre

    CERN Multimedia

    2006-01-01

    With the unveiling of its new sign, the CERN Control Centre was officially inaugurated on Thursday 16 March. To celebrate its startup, CERN Council members visited the sleek centre, a futuristic-looking room filled with a multitude of monitoring screens.

  6. The Aube centre. 1997 statement

    International Nuclear Information System (INIS)

    Since January 1992 the Aube centre ensures the storage of 90% of the short life radioactive wastes produced in France. This educational booklet describes the organization of the activities in the centre from the storage of wastes to the radioactivity surveillance of the environment (air, surface and ground waters, river sediments, plants and milk). (J.S.)

  7. Hole centres in magnesium oxide

    International Nuclear Information System (INIS)

    When magnesium oxide crystals are exposed to ionizing radiation the electron-loss (hole) centres are normally identified as O·- ions. In this paper, I examine the EPR evidence for this, and compare the data with those for the hole centres in alkali- halides (VK centres). The latter are clearly σ* radical anions, such as F.-F-.The analogous centre in MgO is O.-O3-, which does not seem to have been considered. The results compare well, suggesting that the O·- centres are really O.-O3- radicals. In particular, the 17O data for the oxygen centre and the 19F data for F2·- give similar estimates of the 2s and 2p character of the orbitals on oxygen and fluorine, suggesting that the spin-density on oxygen is ca. 50%. The exception is the direction of the principal axes of these centres, which are quite different from each other. It is suggested that the primary hole-centres in MgO migrate by electron transfer to neighbouring cation vacancies where they are stable, and that at these sites the (1, 0, 0) directions are most favourable for σ- bonding

  8. Stress transmission in soil

    DEFF Research Database (Denmark)

    Lamandé, Mathieu; Schjønning, Per

    We urgently need increased quantitative knowledge on stress transmission in real soils loaded with agricultural machinery. 3D measurements of vertical stresses under tracked wheels were performed in situ in a Stagnic Luvisol (clay content 20 %) continuously cropped with small grain cereals. The......). Seven load cells were inserted horizontally from a pit with minimal disturbance of soil in each of three depths (0.3, 0.6 and 0.9 m), covering the width of the wheeled area. The position of the wheel relative to the transducers was recorded using a laser sensor. Finally, the vertical stresses near the...... soil-tyre interface were measured in separate tests by 17 stress transducers across the width of the tyres. The results showed that the inflation pressure controlled the level of maximum stresses at 0.3 m depth, while the wheel load was correlated to the measured stresses at 0.9 m depth. This supports...

  9. Estimated errors in vertical bar Vcd vertical bar / vertical bar Vcs vertical bar from semileptonic D decays

    International Nuclear Information System (INIS)

    We estimate statistical and systematic errors in the extraction of the CKM ratio vertical bar Vcd vertical bar / vertical bar Vcs vertical bar from exclusive D-meson semileptonic decays using lattice QCD and anticipated new experimental results

  10. Clinical Observation of Pregnant Woman Quantitative HBV-DNA and Mother to Infant Vertical Transmission%孕妇HBV-DNA定量与母婴垂直传播的临床观察

    Institute of Scientific and Technical Information of China (English)

    高卓; 俞洋

    2015-01-01

    significant difference(P0.05).Conclusion:The content of HBV-DNA are in the normal range,HBIG can effectively block mother to child transmission of HBsAg positive and HBV small sanyang,but not to block mother to child transmission of hepatitis B small three positive and HBsAg positive hepatitis B patients with HBeAg and HBV-DNA quantitative abnormalities.

  11. Comparison of 454 Ultra-Deep Sequencing and Allele-Specific Real-Time PCR with Regard to the Detection of Emerging Drug-Resistant Minor HIV-1 Variants after Antiretroviral Prophylaxis for Vertical Transmission.

    Directory of Open Access Journals (Sweden)

    Andrea Hauser

    Full Text Available Pregnant HIV-infected women were screened for the development of HIV-1 drug resistance after implementation of a triple-antiretroviral transmission prophylaxis as recommended by the WHO in 2006. The study offered the opportunity to compare amplicon-based 454 ultra-deep sequencing (UDS and allele-specific real-time PCR (ASPCR for the detection of drug-resistant minor variants in the HIV-1 reverse transcriptase (RT.Plasma samples from 34 Tanzanian women were previously analysed by ASPCR for key resistance mutations in the viral RT selected by AZT, 3TC, and NVP (K70R, K103N, Y181C, M184V, T215Y/F. In this study, the RT region of the same samples was investigated by amplicon-based UDS for resistance mutations using the 454 GS FLX System.Drug-resistant HIV-variants were identified in 69% (20/29 of women by UDS and in 45% (13/29 by ASPCR. The absolute number of resistance mutations identified by UDS was twice that identified by ASPCR (45 vs 24. By UDS 14 of 24 ASPCR-detected resistance mutations were identified at the same position. The overall concordance between UDS and ASPCR was 61.0% (25/41. The proportions of variants quantified by UDS were approximately 2-3 times lower than by ASPCR. Amplicon generation from samples with viral loads below 20,000 copies/ml failed more frequently by UDS compared to ASPCR (limit of detection = 650 copies/ml, resulting in missing or insufficient sequence coverage.Both methods can provide useful information about drug-resistant minor HIV-1 variants. ASPCR has a higher sensitivity than UDS, but is restricted to single resistance mutations. In contrast, UDS is limited by its requirement for high viral loads to achieve sufficient sequence coverage, but the sequence information reveals the complete resistance patterns within the genomic region analysed. Improvements to the UDS limit of detection are in progress, and UDS could then facilitate monitoring of drug-resistant minor variants in the HIV-1 quasispecies.

  12. The Aube centre; Le Centre de l`Aube

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-07-01

    This educational booklet is devoted to a general presentation of the Aube radioactive wastes storage centre. After a short presentation of the Andra, the French national agency for the management of radioactive wastes, it gives some general information about radioactive wastes (origin, classification), containers (quality assurance and different types), wastes transportation (planning, safety), and about the Aube centre itself: description, treatment and conditioning of drums (compacting and injection), storage facilities, geological situation of the site, and environmental controls. (J.S.)

  13. Minister unveils new nanotech centres

    Science.gov (United States)

    Dumé, Belle

    2009-06-01

    Three new nanotechnology research centres are to be set up in France as part of a €70m government plan to help French companies in the sector. Researchers at the new centres, which will be located in Grenoble, Saclay (near Paris) and Toulouse, will be encouraged to collaborate with industry to develop new nanotech-based products. Dubbed NANO-INNOV, the new plan includes €46m for two new buildings at Saclay, with the rest being used to buy new equipment at the three centres and to fund grant proposals from staff to the French National Research Agency (ANR).

  14. Radiation sterilization centres worldwide

    International Nuclear Information System (INIS)

    Commercial radiation sterilization has been used for more than 50 years. The Ethicon Division of Johnson and Johnson inaugurated medical device sterilization in 1954 for use with sutures. Over the decades, there has been enormous growth in the disposable medical products market. With this, there has been significant growth in the use of ionizing radiation as a method for sterilization. At present, 40-50% of all disposable medical products manufactured in North America are radiation sterilized. There are now some 160 commercial 60Co irradiators for radiation sterilization operating in 47 countries worldwide, containing approximately 240-260 MCi (8.9-9.6 x 1018 Bq) of gamma emitting 60Co. Included in this are service type facilities operated in research and development centres. Because of the ability to downscale 60Co units, there are many R and D and pilot scale small facilities as well, almost equal in number (approximately 150). When other uses are taken into account, there are in total over 200 gamma irradiators being operated for a variety of purposes in 55 different countries: 100-120 gamma irradiators are located in Europe and in the United States of America. Syringes, surgical gloves, gowns, masks, sticking plasters, dressings, medical 'tetrapacks', bottle teats for premature babies, artificial joints, food packaging, raw materials for pharmaceuticals and cosmetics, and even wine corks, are gamma sterilized. An increasing number of e-beam accelerators are also being operated, but at present e-beam is used for only a minority of radiation sterilized product. The use of e-beam as a radiation source has many attractive features, such as near instantaneous dose delivery, scalability for different throughput, and the capability to integrate in an on-line process. E-beam processing is, however, limited by the penetration of electrons, which is proportional to the accelerator voltage. The highest electron energy used in commercial applications, 10 MeV, penetrates

  15. CERI: Ionizing Radiation Calibration Centre

    International Nuclear Information System (INIS)

    The CERI has been granted by the National Bureau of Metrology (BNM) as an Ionizing Radiation Calibration Centre and as an Estimation and Qualification Centre for the ionizing radiation measurement devices. This article gives some information on the scope covered by the BNM's grant and on the various equipment on which the laboratory relies. It describes the calibration and estimation activities and mentions many kinds of services which are offered to the users mainly in the medical and industrial fields

  16. The centre of the action

    CERN Multimedia

    2008-01-01

    The CERN Control Centre (CCC) has all the ingredients of an action movie control room: hundreds of screens, technicians buzzing in and out, huge floor-to-ceiling windows revealing the looming vista of a mountain range, flashing lights, microphones… This is the place where not just the LHC, but the whole of CERN’s accelerator complex and technical support is based - truly the centre of the action at CERN.

  17. Contemporary design for 'landmark' centre.

    Science.gov (United States)

    2009-08-01

    As one of the UK's largest builders of healthcare facilities, construction company Morgan Ashurst is accustomed to delivering complex, challenging hospital projects. The construction of a new oncology centre at Musgrove Park Hospital, Taunton for Taunton and Somerset NHS Foundation Trust-- said to be the first new stand-alone radiotherapy centre to be built in the UK for almost 20 years--was no exception. Health Estate Journal reports. PMID:19711668

  18. IMPLICATIONS OF PATIENT CENTRING ON ORGAN DOSE IN COMPUTED TOMOGRAPHY.

    Science.gov (United States)

    Kataria, Bharti; Sandborg, Michael; Althén, Jonas Nilsson

    2016-06-01

    Automatic exposure control (AEC) in computed tomography (CT) facilitates optimisation of dose absorbed by the patient. The use of AEC requires appropriate 'patient centring' within the gantry, since positioning the patient off-centre may affect both image quality and absorbed dose. The aim of this experimental study was to measure the variation in organ and abdominal surface dose during CT examinations of the head, neck/thorax and abdomen. The dose was compared at the isocenter with two off-centre positions-ventral and dorsal to the isocenter. Measurements were made with an anthropomorphic adult phantom and thermoluminescent dosemeters. Organs and surfaces for ventral regions received lesser dose (5.6-39.0 %) than the isocenter when the phantom was positioned +3 cm off-centre. Similarly, organ and surface doses for dorsal regions were reduced by 5.0-21.0 % at -5 cm off-centre. Therefore, correct vertical positioning of the patient at the gantry isocenter is important to maintain optimal imaging conditions. PMID:26743256

  19. Training centres - organization and management

    International Nuclear Information System (INIS)

    In the lecture 'Training centres - organization and management' some principles and requirements which influence the organization, management and activity pattern of nuclear training centres, are briefly introduced. It is demonstrated, step by step, how these general principles are implemented in the development of the Czechoslovak nuclear power programme, it means, how the training of the NPP personnel proceeds in Czechoslovak nuclear training centres. General principles which are selected: a connection between the capacity of the training centre and the scope and needs of the nuclear power programme, a position of the training center within the institutional set-up, a structure and organization of the training system which complies with the system of NPP construction, reflect the pattern and the activity of the nuclear training centre and nuclear power technical level, a research group of workers in the nuclear training centre, main tasks and technical facilities, management of the training process and a transfer of knowledge and research results into the training process. The lecture is supplemented by pictures and slides. (orig.)

  20. RTEMS Centre - Support and Maintenance Centre to RTEMS Operating System

    Science.gov (United States)

    Silva, H.; Constantino, A.; Freitas, D.; Coutinho, M.; Faustino, S.; Mota, M.; Colaço, P.; Sousa, J.; Dias, L.; Damjanovic, B.; Zulianello, M.; Rufino, J.

    2009-05-01

    RTEMS CENTRE - Support and Maintenance Centre to RTEMS Operating System is a joint ESA/Portuguese Task Force initiative to develop a support and maintenance centre to the Real-Time Executive for Multiprocessor Systems (RTEMS). This paper gives a high level visibility of the progress, the results obtained and the future work in the RTEMS CENTRE [6] and in the RTEMS Improvement [7] projects. RTEMS CENTRE started officially in November 2006, with the RTEMS 4.6.99.2 version. A full analysis of RTEMS operating system was produced. The architecture was analysed in terms of conceptual, organizational and operational concepts. The original objectives [1] of the centre were primarily to create and maintain technical expertise and competences in this RTOS, to develop a website to provide the European Space Community an entry point for obtaining support (http://rtemscentre.edisoft.pt), to design, develop, maintain and integrate some RTEMS support tools (Timeline Tool, Configuration and Management Tools), to maintain flight libraries and Board Support Packages, to develop a strong relationship with the World RTEMS Community and finally to produce some considerations in ARINC-653, DO-178B and ECSS E-40 standards. RTEMS Improvement is the continuation of the RTEMS CENTRE. Currently the RTEMS, version 4.8.0, is being facilitated for a future qualification. In this work, the validation material is being produced following the Galileo Software Standards Development Assurance Level B [5]. RTEMS is being completely tested, errors analysed, dead and deactivated code removed and tests produced to achieve 100% statement and decision coverage of source code [2]. The SW to exploit the LEON Memory Management Unit (MMU) hardware will be also added. A brief description of the expected implementations will be given.

  1. 乙型肝炎病毒母婴垂直传播与乙肝抗原及乙肝DNA载量的关系研究%Study on the Correlation of Mother-to-infant Vertical Transmission of Hepatitis B Virus with Hepatitis B Antigen and HBV DNA Load

    Institute of Scientific and Technical Information of China (English)

    牛兆仪; 王芳; 靳晴; 初正敏; 沈冉; 李丽荣

    2014-01-01

    目的:研究妊娠合并乙型肝炎病毒感染孕妇母婴垂直传播相关因素。方法选择妊娠合并乙型肝炎病毒感染孕妇100例作为研究对象,对患者病病历资料作回顾性分析。结果HBsAg单阳性孕妇母婴垂直传播几率1.75%较HBsAg、HBeAg双阳性母婴垂直传播几率46.51%低,差异有统计学意义(P<0.05)。外周血HBV DNA≥106copies/mL的产孕妇分娩后胎儿HBV DNA阳性率50.0%较HBV DNA≤105copies/mL和105copies/mLvertical transmission of hepatitis B virus. Methods 100 pregnant women with hepatitis B virus infection were selected as the subjects. And the medical records of them were analyzed retrospectively. Results The probability of mother-to-infant vertical transmission of the pregnant women with positive HBsAg was 1.75%, lower than 46.51% of the pregnant women with double positive HBsAg, HBeAg, the difference was statistically significant (P<0.05). The fetal HBV DNA positive rate of the pregnant women with HBV DNA ≥ 106copies/ml in peripheral blood after childbirth was 50.0%, higher than HBV DNA≤105copies/ml and 105copies/ml

  2. The optimal vertical structure in the electricity industry when the incumbent has a cost advantage

    International Nuclear Information System (INIS)

    This paper studies how the vertical structure of the electricity industry affects the social welfare when the incumbent has a cost advantage in generation relative to the entrants. The model consists of a generation sector and a transmission sector. In the generation sector the incumbent and entrants compete in a Cournot fashion taking as given the access charge to the transmission network set in advance by the regulator to maximize the social welfare. Two vertical structures, integration and separation, are considered. Under vertical separation the transmission network is established as an organization independent of every generator, whereas under vertical integration it is a part of the incumbent's organization. The optimal vertical structure is shown to depend on the number of entrants. If the number of entrants is smaller than a certain threshold, vertical separation is superior in welfare to vertical integration, and vice versa. This is because the choice of vertical structure produces a trade-off in the effects on competition promotion and production efficiency. If a break-even constraint is imposed in the transmission sector, however, vertical integration is shown to be always superior in welfare. - Highlights: • We examine the optimal vertical structure in the electricity industry. • We model a generation sector in which the incumbent has a cost advantage. • A trade-off between production efficiency and competition promotion occurs. • The optimal vertical structure depends on the number of entrants. • Vertical integration is always superior if a break-even constraint is imposed

  3. Nuclear Information Centre is building branch reference centre

    International Nuclear Information System (INIS)

    Reference services are being prepared by the Nuclear Information Centre (NIC) in order to improve information services for nuclear science and technology. The objective is to analyse the user's request, to determine suitable information sources and to provide the end user with a reference to the appropriate information centre, specialized organization or a specialist, or to directly provide the requested information using own information sources. The reference services will use a number of the Centre's own information data files, the data bank of relevant information sources, a personal and corporate file, the record of Czechoslovak nonconventional materials, the data bank of NIC publishing operations, the auxiliary NIC services record, a catalogue of books and journals, and the data bases at NIC. Most information files will be automated and stored on IBM-compatible personal computers. (J.B.). 1 fig., 3 refs

  4. Trackless centre pivot-steered underground vehicle with electric-motor drive. Gleisloses knickgelenktes Untertagefahrzeug mit Elektromotorantrieb

    Energy Technology Data Exchange (ETDEWEB)

    Hillmann, W.; Paus, H.; Drews, E.

    1989-05-03

    Trackless, centre pivot-steered underground vehicle with electric-motor drive of the tractor section, the supply of energy to which takes place via sliding contact line and a current-collecting device which can be driven thereon, and via a connecting cable which is connected electrically and mechanically to the latter and can be unwound from a reel against a restoring force, characterised by the combination of the following features: (a) the connecting cable (supply cable) is connected to the current-collecting device via a slip-ring member which can be rotated about a vertical axle; (b) a cable reel which winds in a spiral and is driven by a hydraulic motor is mounted on the tractor section so as to be rotatable about a vertical axle, the axle being equipped with a slip-ring member; (c) a hydraulically pivotable guide arm is arranged coaxially to the cable reel; (d) a hydrostatic axial piston transmission for the travelling mechanism and drive in (b) and (c) is coupled to a three phase current motor. 1 fig.

  5. The ideal Atomic Centre; Le Centre Atomique ideal

    Energy Technology Data Exchange (ETDEWEB)

    Mas, R. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1965-07-01

    The author presents considerations which should prove to be of interest to all those who have to design, to construct and to operate a nuclear research centre. A large number of the ideas presented can also be applied to non-nuclear scientific research centres. In his report the author reviews: various problems with which the constructor is faced: ground-plan, infrastructure, buildings and the large units of scientific equipment in the centre, and those problems facing the director: maintenance, production, supplies, security. The author stresses the relationship which ought to exist between the research workers and the management. With this aim in view he proposes the creation of National School for Administration in Research which would train administrative executives for public or private organisations; they would be specialised in the fields of fundamental or applied research. (author) [French] L'auteur propose une base de reflexions a tous ceux qui doivent concevoir, realiser et faire vivre un Centre d'Etudes Nucleaires. Un grand nombre des idees exprimees peut d'ailleurs s'appliquer a un Centre d'Etudes Scientifiques non nucleaires. Dans son ouvrage, l'auteur passe en revue les differents problemes qui se posent au constructeur: plan, masse, infrastructure, batiments et grands appareils du Centre, et ceux qu'a a resoudre le directeur: entretien, fabrication, approvisionnements, securite. L'auteur insiste sur l'aspect des rapports qui doivent exister entre les chercheurs et ceux qui les administrent. Il propose a cette fin la creation d'une Ecole Nationale d'Administration de la Recherche qui formerait des cadres administratifs pour les organismes publics ou prives, specialises dans la Recherche fondamentale ou appliquee. (auteur)

  6. Hybrid vertical cavity laser

    DEFF Research Database (Denmark)

    Chung, Il-Sug; Mørk, Jesper

    2010-01-01

    A new hybrid vertical cavity laser structure for silicon photonics is suggested and numerically investigated. It incorporates a silicon subwavelength grating as a mirror and a lateral output coupler to a silicon ridge waveguide.......A new hybrid vertical cavity laser structure for silicon photonics is suggested and numerically investigated. It incorporates a silicon subwavelength grating as a mirror and a lateral output coupler to a silicon ridge waveguide....

  7. Composition of vertical gardens

    OpenAIRE

    Sandeva, Vaska; Despot, Katerina

    2013-01-01

    Vertical gardens are fully functional gardens in areas where there is less oxygen and space, ideal for residential and urban cities where there is no vegetation; occupy a special place in interiors furniture. The gardens occupy an important aesthetic problem. Aesthetic task in vertical gardens can be achieved by forming sectors of identification in the urban landscape through the choice of a particular plant spatial composition and composition, to create comfort and representation in commu...

  8. Correlation analysis between the load levels of paternal semen HBV-DNA and vertical transmission of HBV from father to infant%父亲精液HBV-D NA载量与HBV父婴垂直传播的相关性分析

    Institute of Scientific and Technical Information of China (English)

    陈顺萍; 张荣莲; 任坤海; 王梅颖

    2014-01-01

    Aim:To explore the impact of the load levels of paternal semen HBV-DNA on vertical transmission of HBV from HBsAg-positive father to infant.Methods:52 families of pregnant women with negative HBsAg and HBV-DNA and husbands with positive,serum HBsAg were selected.Clinical data and blood samples of the parents and their newborns、semen samples of the husbands were collected.Ser-um HBVM and the load levels of paternal blood and semen HBV-DNA were determined.In case-control study,based on the results of neonatal cord blood HBV-DNA detection,1 1 newborns with cord blood posi-tive HBV-DNA were selected as subiects,and 41 newborns with negative HBV-DNA as controls.Results:①The positive rate of neonatal cord blood HBV-DNA was found to be 21.2%(11/52),and that of se-men HBV-DNA was 26.9%(14/52).②The incidence of vertical transmission of HBV in infants with paternal positive semen HBV-DNA was found significantly higher than that in infants with paternal nega-tive semen HBV-DNA(P<0.01).③There was a positive rank correlation between semen and serum of HBV-DNA load levels,while the load levels of semen HBV-DNA was lower than that of serum HBV-DNA load levels.④The analysis of ROC curve showed that the prediction accuracy of semen HBV-DNA in the occurrence of vertical transmission were more accurate than that based on serum HBV-DNA load.Con-clusion:Paternal positive semen HBV-DNA is one of the risk fators for vertical transmission of HBV;re-ducing HBV-DNA load levels in paternal blood and semen before pregnancy may be a way to block father-fetal transmisson of HBV.%目的:探讨乙肝表面抗原(HBsAg)阳性父亲精液乙型肝炎病毒脱氧核糖核酸(HBV-DNA)载量对其新生儿发生HBV父婴垂直传播的影响,以期寻找阻断HBV父婴垂直传播的有效方法.方法:在知情同意的原则,以丈夫血清HBsAg阳性、孕母HBsAg及HBV-DNA均阴性的52个家庭作为研究对象,收集父母及其新生儿的相关资料及血液标

  9. HIV Transmission

    Science.gov (United States)

    ... Abroad Treatment Basic Statistics Get Tested Find an HIV testing site near you. Enter ZIP code or city Follow HIV/AIDS CDC HIV CDC HIV/AIDS See RSS | ... on HIV Syndicated Content Website Feedback HIV/AIDS HIV Transmission Language: English Español (Spanish) Recommend on Facebook ...

  10. The Galactic centre pulsar population

    CERN Document Server

    Chennamangalam, Jayanth

    2013-01-01

    The recent discovery of a magnetar in the Galactic centre region has allowed Spitler et al. to characterize the interstellar scattering in that direction. They find that the temporal broadening of the pulse profile of the magnetar is substantially less than that predicted by models of the electron density of that region. This raises the question of what the plausible limits for the number of potentially observable pulsars - i.e., the number of pulsars beaming towards the Earth - in the Galactic centre region are. In this paper, using realistic assumptions, we show that the potentially observable population of pulsars in the inner parsec has a conservative upper limit of $\\sim$950, and that it is premature to conclude that the number of pulsars in this region is small. We also show that the observational results so far are consistent with this number and make predictions for future radio pulsar surveys of the Galactic centre.

  11. The Belgian nuclear research centre

    International Nuclear Information System (INIS)

    The Belgian Nuclear Research Centre is almost exclusively devoted to nuclear R and D and services and is able to generate 50% of its resources (out of 75 million Euro) by contract work and services. The main areas of research include nuclear reactor safety, radioactive waste management, radiation protection and safeguards. The high flux reactor BR2 is extensively used to test fuel and structural materials. PWR-plant BR3 is devoted to the scientific analysis of decommissioning problems. The Centre has a strong programme on the applications of radioisotopes and radiation in medicine and industry. The centre has plans to develop an accelerator driven spallation neutron source for various applications. It has initiated programmes to disseminate correct information on issues of nuclear energy production and non-energy nuclear applications to different target groups. It has strong linkages with the IAEA, OECD-NEA and the Euratom. (author)

  12. Construction of the Wigner Data Centre

    CERN Multimedia

    2013-01-01

    A remote extension of the CERN data centre has recently been inaugurated. Hosted at the Wigner Research Centre for Physics in Hungary, it provides extra computing power required to cover CERN’s needs. This video presents the construction of the Wigner Data Centre from initial demolishing work through to its completion and details the major technical characteristics of the Data Centre.

  13. Training centres in Latin America

    International Nuclear Information System (INIS)

    Early 1958 the Brazilian representative on the Board of Governors of the International Atomic Energy Agency - supported by the Governors from Argentina and Guatemala -proposed that a study should be made of the possibility of setting up one or more atomic energy training centres in Latin America. On the Board's recommendation, the Director General of the Agency appointed a fact-finding team to make anon-the-spot study. In drafting this report the team was invited to consider the following points: (a) The need for establishing one or more regional training centres; (b) Existing facilities that are being or could be used for training, together with technical data concerning them; (c) The general scientific technological and industrial conditions of the countries visited insofar as they have a bearing on their training needs and capabilities. The authors of the report conclude that 'a training centre in radio-botany should provide vitally needed knowledge and vitally needed specialists to all the agricultural installations in Latin America. A training centre like this might provide an excellent model upon which to base training centres in other areas'. The report recommends that: 1. The Agency should meet the requests of Latin American universities by, for example, supplying equipment and sending experts; 2. At least one specialized training centre should be established as soon as possible. Taking as an example the field of radio-botany, such a centre would provide trained specialists in radio-botany to agricultural institutions throughout Latin America and also provide basic research results vital to agriculture. The cost of new facilities might be of the order of $7 500 000, with an annual budget of approximately $650 000. Staff required: 40 scientists and 175 employees; 3. Whenever it appears feasible to gather necessary staff of high creative ability and established productivity and when funds can be made available for facilities, equipment and operating costs, at

  14. Transmission of vertical soil stress under agricultural tyres

    DEFF Research Database (Denmark)

    Keller, Thomas; Berli, M.; Ruiz, S.;

    2014-01-01

    depth estimated from tyre characteristics as the upper boundary condition, and v was obtained at minimum deviation between measurements and simulations. For the five soils, we obtained an average v of 3.5 (for stress transmitting from 0.1 to 0.7 m depth). This was only slightly different from v = 3 for...

  15. The DEMETER Science Mission Centre

    Czech Academy of Sciences Publication Activity Database

    Lagoutte, D.; Brochot, J.; Y.; de Carvalho, D.; Elie, F.; Harivelo, F.; Hobara, Y.; Madrias, L.; Parrot, M.; Pincon, J. L.; Berthelier, J. J.; Peschard, D.; Seran, E.; Gangloff, M.; Sauvaud, J. A.; Lebreton, J. P.; Štverák, Štěpán; Trávníček, Pavel M.; Grygorczuk, J.; Slominski, J.; Wronowski, R.; Barbier, S.; Bernard, P.; Gaboriaud, A.; Wallut, J. M.

    2006-01-01

    Roč. 54, č. 5 (2006), s. 428-440. ISSN 0032-0633 Institutional research plan: CEZ:AV0Z30420517 Keywords : Mission Centre * Data processing Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics Impact factor: 1.509, year: 2006

  16. Vinohrady Sokol centre in Prague

    Czech Academy of Sciences Publication Activity Database

    Svobodová, Markéta

    Prague: Prostor - architektura, interiér, design, 2012 - (Švácha, R.), s. 178-181 ISBN 978-80-87064-09-2 Institutional support: RVO:68378033 Keywords : Sokol centre * functionalism * František Marek * Václav Vejrych * Zbyšek Jirsák Subject RIV: AL - Art, Architecture, Cultural Heritage

  17. Tracing the vertical composition of disc galaxies through colour gradients

    CERN Document Server

    De Grijs, R; Grijs, Richard de; Peletier, Reynier F.

    1999-01-01

    (Abbreviated) Optical observations of a statistically complete sample of edge-on disc galaxies are used to study the intrinsic vertical colour gradients in the galactic discs, to constrain the effects of population gradients, residual dust extinction and gradients in the galaxies' metal abundance. It appears that the intrinsic vertical colour gradients are either non-existent, or small and relatively constant as a function of position along the galaxies' major axes. Our results are consistent with the absence of any vertical colour gradient in the discs of the early-type sample galaxies. In most galaxies small-scale variations in the magnitude and even the direction of the vertical gradient are observed: at larger galactocentric distances they generally display redder colours with increasing z height, whereas the opposite is often observed in and near the galactic centres. For a significant fraction of our sample galaxies another mechanism in addition to the effects of stellar population gradients is required...

  18. Oregon ESA 2010 BKD vertical transmission - Test of analyses for bacterial kidney disease as predictors of vertical transmission

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Although the pathogen causing bacterial kidney disease is known to be transmitted from broodstock female to offspring, there is large uncertainty around the...

  19. The CCCB is a cultural centre, not a tourist centre

    Directory of Open Access Journals (Sweden)

    Elena Xirau

    2004-04-01

    Full Text Available Last February, Barcelona's Centre of Contemporary Culture (CCCB celebrated its first ten years in existence. During this time, this institution has looked to be a showcase to the most modern and innovative cultural expressions focused on reflecting on the concept of the city. In this interview, Josep Ramoneda offers his personal view, as the CCCB's director. He talks of how this cultural project was born, of how the concept of the institution took shape in the CCCB, of its relations with Barcelona's Strategic Plan, of how the project has evolved, of the architectural remodelling of the Casa de la Caritat building for its conversion into a cultural centre, of the relations with other institutions and its future.

  20. The CCCB is a cultural centre, not a tourist centre

    OpenAIRE

    Elena Xirau

    2004-01-01

    Last February, Barcelona's Centre of Contemporary Culture (CCCB) celebrated its first ten years in existence. During this time, this institution has looked to be a showcase to the most modern and innovative cultural expressions focused on reflecting on the concept of the city. In this interview, Josep Ramoneda offers his personal view, as the CCCB's director. He talks of how this cultural project was born, of how the concept of the institution took shape in the CCCB, of its relations with Bar...

  1. SAGE III Meteor-3M L1B Solar Event Transmission Data (Native) V004

    Data.gov (United States)

    National Aeronautics and Space Administration — Level 1B pixel group transmission profiles for a single solar event (Suggested Usage: Vertical transmission profiles for input into an inversion algorithm)

  2. SAGE III Meteor-3M L1B Solar Event Transmission Data (Native) V003

    Data.gov (United States)

    National Aeronautics and Space Administration — Level 1B pixel group transmission profiles for a single solar event (Suggested Usage: Vertical transmission profiles for input into an inversion algorithm)

  3. Determinantes de la transmisión vertical del VIH en Cataluña (1997-2001: ¿es posible su eliminación? Determinants of HIV mother-to-child transmission in Catalonia, Spain [1997-2001]: is it possible to eliminate it?

    Directory of Open Access Journals (Sweden)

    F. Ramos

    2003-07-01

    Full Text Available Objetivos: Identificar y describir los factores que han hecho posible la existencia de nuevas infecciones de VIH por transmisión vertical desde la implementación del tratamiento antirretroviral en la gestante seropositiva (1997-2001 en Cataluña. Métodos: Revisión sistemática de casos identificados en servicios de pediatría de todos los hospitales de Cataluña. Resultados: Se identificaron 28 casos de infección pediátrica por VIH: 9, 9, 8, 2 y 0 por año de nacimiento de 1997 a 2001, respectivamente. De 16 madres con diagnóstico de infección por VIH conocido antes o durante el embarazo, 9 realizaron profilaxis antirretroviral durante éste (5 con buena adhesión, uno desconocido y el resto con mala adhesión y 7 no realizaron profilaxis (6 por rechazo y uno no se conoce. De 12 diagnosticadas después del parto, 5 fueron embarazos no controlados y el resto poco o bien controlados. De estos últimos, en 6 no se practicó serología para VIH y en uno fue negativa en el primer trimestre. Conclusiones: La transmisión vertical del VIH en Cataluña ha disminuido en los últimos años, pero se han producido infecciones por la mala implementación en algún caso de las medidas preventivas conocidas. Debería ofrecerse la prueba diagnóstica para VIH a toda gestante no sólo en el primer trimestre de embarazo sino también al final, si se sospecha exposición al virus, y en caso de gestaciones no controladas hay que usar pruebas diagnósticas de lectura rápida en la sala de partos.Objectives: To identify and describe the factors that have led to new cases of HIV infection through mother-to-child transmission since the introduction of antiretroviral therapy in HIV-seropositive pregnant women (1997-2001 in Catalonia. Methods: Systematic review of cases identified in the pediatric services of all the hospitals in Catalonia. Results: Twenty-eight cases of pediatric HIV infection were identified: 9, 9, 8, 2 and 0 per year of birth from 1997 to 2001

  4. Transcending Transmission

    DEFF Research Database (Denmark)

    Schoeneborn, Dennis; Trittin, Hannah

    2013-01-01

    Purpose – Extant research on corporate social responsibility (CSR) communication primarily relies on a transmission model of communication that treats organizations and communication as distinct phenomena. This approach has been criticized for neglecting the formative role of communication in the....... Organizations are stabilized by various non-human entities that “act” on their behalf. Accordingly, CSR communication should also take into account non-human agency and responsibility. Originality/value – This paper links the literature on CSR communication to broader debates in organizational communication...... studies and, in particular, to the CCO perspective. By applying the CCO view, it reconceptualizes CSR communication as a complex process of meaning negotiation....

  5. Vertical market participation

    DEFF Research Database (Denmark)

    Schrader, Alexander; Martin, Stephen

    1998-01-01

    Firms that operate at both levels of vertically related Cournot oligopolies will purchase some input supplies from independent rivals, even though they can produce the good at a lower cost, driving up input price for nonintegrated firms at the final good level. Foreclosure, which avoids this stra...

  6. Global Vertical Reference Frame

    Czech Academy of Sciences Publication Activity Database

    Burša, Milan; Kenyon, S.; Kouba, J.; Šíma, Zdislav; Vatrt, V.; Vojtíšková, M.

    -, č. 5 (2009), s. 53-63. ISSN 1801-8483 R&D Projects: GA ČR GA205/08/0328 Institutional research plan: CEZ:AV0Z10030501 Keywords : sea surface topography * satellite altimetry * vertical frames Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics

  7. HBV父婴垂直传播水平与HBV-DNA载量的相关研究%A correlation analysis between the rate of vertical transmission of HBV and HBsAg-positive father to infant and the rate of neonatal cord blood HBV-DNA

    Institute of Scientific and Technical Information of China (English)

    张荣莲; 罗颖; 谢婧娴; 陈起燕; 成玲; 郭胜斌; 黄欣欣

    2010-01-01

    Objective To study the influence of HBV-DNA with different load levels of HBsAg-positive among fathers on the rate of neonatal cord blood HBV-DNA.Methods Using HBsAg and HBV-DNA as screening indicators for pregnant women and their husbands from an obstetric clinic.161 pregnant women whose HBsAg and HBV-DNA were negative,but HBsAg was positive among their husbands and their newborns,were selected.Blood samples from those pregnant women,their husbands and their newborns were collected to detect the related indicators.Using ELISA to detect hepatitis B virus markers(HBVM),and FQ-PCR to detect the levels of HBV-DNA load.According to neonatal cord blood HBV-DNA detection guideline,newborns with cord blood HBV-DNA positive were selected as cases,others as controls.Results(1)Result of the study showed that there was a dose-response relationship between paternal serum HBV-DNA load levels and neonatal cord blood HBV-DNA positive rates in newborns(trend χ~2=64.117,P=0.000).The rate of vertical transmission of HBV from HBsAg-positive father to infant in the paternal serum HBV-DNA>1.0×107 copies/ml group was significantly higher than HBV-DNA<1.0×107 copies/ml group(χ~2=71.539,P=0.000).(2)There was a positive rank correlation between semen positive HBeAg and vertical transmission of HBV from HBsAg-positive father to infant(χ~2=6.892,P=0.009).Conclusion There was a dose-response relationship between paternal serum HBV-DNA load levels and neonatal cord blood HBV-DNA positive in newborns.Paternal serum HBV-DNA≥1.0×107 copies/ml and with HBeAg positive status were risk factors of vertical transmission of HBV from HBsAg-positive father to infant.%目的 探讨HBsAg阳性父亲血HBV-DNA的不同载量水平对其新生儿发生HBV父婴垂直传播的影响.方法 对161例HBsAg阳性的父亲及其新生儿(母亲血清HBVM全阴性或仅HBsAb阳性及HBV-DNA均为阴性)HBV感染状况进行调查分析.采用ELISA检测HBVM,FQ-PCR法检测血清HBV DNA

  8. Vertical Transport of Subwavelength Localized Surface Electromagnetic Modes

    CERN Document Server

    Gao, Fei; Zhang, Youming; Shi, Xihang; Yang, Zhaoju; Zhang, Baile

    2015-01-01

    Transport of subwavelength electromagnetic (EM) energy has been achieved through near-field coupling of highly confined surface EM modes supported by plasmonic nanoparticles, in a configuration usually staying on a two-dimensional (2D) substrate. Vertical transport of similar modes along the third dimension, on the other hand, can bring more flexibility in designs of functional photonic devices, but this phenomenon has not been observed in reality. In this paper, designer (or spoof) surface plasmon resonators (plasmonic meta-atoms) are stacked in the direction vertical to their individual planes in demonstrating vertical transport of subwavelength localized surface EM modes. Dispersion relation of this vertical transport is determined from coupled mode theory and is verified with near-field transmission spectrum and field mapping with a microwave near-field scanning stage. This work extends the near-field coupled resonator optical waveguide (CROW) theory into the vertical direction, and may find applications ...

  9. The INTEGRAL Science Data Centre

    OpenAIRE

    Beckmann, V.

    2002-01-01

    The INTEGRAL Science Data Centre (ISDC) processes, archives and distributes data from the INTEGRAL mission. At the ISDC incoming data from the satellite are processed and searched for transient sources and Gamma-Ray bursts. The data are archived and distributed to the guest observers. As soon as the data are public, any astronomer can access the data via the internet. ISDC also provides the tools which are necessary for the data analysis and offers user support concerning questions related to...

  10. Radwaste Treatment Centre Jaslovske Bohunice

    International Nuclear Information System (INIS)

    In this leaflet the Bohunice Radwaste Treatment Centre (BSC RAO) is presented. BSC RAO is designed to process and treat liquid and solid radwaste, arising from the NPP A-1 decommissioning, from NPPs V-1, V-2, and Mochovce operations, as well as institutional radwaste of diverse institutional (hospitals, research institutes) in the Slovak Republic. Transport, sorting, incineration, compacting, concentration and cementation of radwaste as well as monitoring of emission are described

  11. Human immunoseficiency virus infection in Saudi Arabain children: transmission, clinical manifestations and outcome

    International Nuclear Information System (INIS)

    Vertical transmission from mother to infant is the most common mode of transmission of HIV infection in children. Data on pediatric HIV in the Middle East and Gulf region are scarce. We describe the spectrum, characteristics and outcome of HIV infection in Saudi children. We collected descriptive data on HIV-infected or exposed children seen at the King Faisal Hospital and Research Centre (KFSH and RC) between 1986 and 2003. Sixty-three children have proven HIV infection. The source of infection was perinatal transmission in 63.5% of cases and contaminated blood or blood products transfusion in 34.5%. Median age at diagnosis was 6 years. In 42 patients for whom complete records were available, 90% were delivered by spontaneous vaginal delivery and 10% by cesarean delivery. Ninety-three percent of infected infants were breastfed throughout infancy. The complete medical records were available for 66% of children; for the remainder, part of the records could not be retrieved. Thirteen percent had an AIDS-defining opportunistic infection, with disseminated cytomegalovirus (CMW) infection being the most common (37.5%). All cases received antiretroviral therapy starting in 1997. Of those who received highly active antiretroviral therapy, 79% were compliant with treatment and had a sustained virologic response below the detectable level. Seventy-five percent of those diagnosed before 1995 died compared with 7.7% diagnosed later. Effective preventive measures, such as antiretroviral prophylaxis, cesarean delivery, and abstention from breastfeeding are not being applied. This could be largely due to lack of knowledge among patients and heath care providers. Physicians must recognize the signs and symptoms of HIV infection, and have a high index of suspicion so that infected children are diagnosed early and referred to a specialized centre for treatment and follow-up. (author)

  12. Insertion of the force applied to handles into centre of pressure calculation modifies the amplitude of centre of pressure shifts.

    Science.gov (United States)

    Noé, Frédéric; Quaine, Franck

    2006-11-01

    This study examined situations where handles were used as additional postural supports. It aimed at determining the amplitude of centre of pressure (COP) shifts when considering or not the vertical handles reaction force. Eight healthy male subjects (24+/-6 years, body mass 65+/-5kg and height 175+/-7cm) voluntarily took part in the experiment. Subjects had to voluntarily rock on their heels or rise on their toe-tips while using handles. The vertical component of the handles forces and ground reaction force was measured and the shifts of the COP were calculated while inserting or not the handles forces. Significant differences were observed when comparing the amplitude of COP shifts calculated with or without the insertion of the handles forces. This study shows that the measurement of the handles forces should not be omitted, for a rigorous analysis of postural tasks performed in conditions including additional postural supports like handles. PMID:16300948

  13. National Model for Transparent Vertical Prioritisation in Swedish Health Care

    OpenAIRE

    Carlsson, Per; Kärvinge, Christina; Broqvist, Mari; Eklund, Kristina; Hallin, Bo; Jacobsson, Catrine; Jacobsson Ekman, Gunilla; Källgren Peterson, Christina; Lindh, Marion; Nordlander, Britt; Rosén, Per; Sjöblom, Urban; Sohlberg, Anna

    2007-01-01

    The proposed national model described in this report has been developed by a working group comprised of staff from the National Board of Health and Welfare, the National Centre for Priority Setting in Health Care, and other organisations involved in vertical prioritisation – including the Östergötland County Council, Stockholm County Council, Västra Götaland, the Health Services Region of Southern Sweden, the Swedish Society of Medicine, the Swedish Society of Nursing, and the Swedish Associa...

  14. The Notting Dale Urban Studies Centre

    Science.gov (United States)

    Webb, Chris; Lynas, Sue

    1976-01-01

    Founded in 1974, the Centre is one of the most intensively used resource centres in the United Kingdom. Adults and students from elementary to college level use its facilities to learn about the urban environment. (BD)

  15. Communicating astronomy by the Unizul Science Centre

    Science.gov (United States)

    Beesham, A.; Beesham, N.

    2015-03-01

    The University of Zululand, situated along the east coast of KwaZulu-Natal, has a thriving Science Centre (USC) situated in the developing port city of Richards Bay. Over 30 000 learners visit the centre annually, and it consists of an exhibition area, an auditorium, lecture areas and offices. The shows consist of interactive games, science shows, competitions, quizzes and matriculation workshops. Outreach activities take place through a mobile science centre for schools and communities that cannot visit the centre.

  16. Vertical organic transistors

    Science.gov (United States)

    Lüssem, Björn; Günther, Alrun; Fischer, Axel; Kasemann, Daniel; Leo, Karl

    2015-11-01

    Organic switching devices such as field effect transistors (OFETs) are a key element of future flexible electronic devices. So far, however, a commercial breakthrough has not been achieved because these devices usually lack in switching speed (e.g. for logic applications) and current density (e.g. for display pixel driving). The limited performance is caused by a combination of comparatively low charge carrier mobilities and the large channel length caused by the need for low-cost structuring. Vertical Organic Transistors are a novel technology that has the potential to overcome these limitations of OFETs. Vertical Organic Transistors allow to scale the channel length of organic transistors into the 100 nm regime without cost intensive structuring techniques. Several different approaches have been proposed in literature, which show high output currents, low operation voltages, and comparatively high speed even without sub-μm structuring technologies. In this review, these different approaches are compared and recent progress is highlighted.

  17. Vertical School of Art

    OpenAIRE

    Feijoo, Manuel

    2013-01-01

    Vertical Buildings (skyscrapers) challenge our perception of space, our perception of scale, our idea of movement, they challenge the way we live. Currently urban cities are becoming more and more dense. Lack of space is a big issue and now buildings are being torn down and are replaced by skyscrapers. And these new skyscrapers are being redefined to house a living and working environment. Cubism challenges our perception of depth, our tactile sense, our ideas of proportion. Cubism, as a 20th...

  18. NET vertical stability

    International Nuclear Information System (INIS)

    The elongated cross-section of the plasma in NET leads to vertical positional instability so that a passive and active stabilizing system is required. The passive action is performed essentially by the segmented first wall, while the active action is performed by two feedback driven toroidal bars. The performance of such a system is presented for a reference case, as well as a sensitivity analysis with respect to some parameters. (author)

  19. NET vertical stability

    International Nuclear Information System (INIS)

    The elongated cross-section of the plasma in NET leads to vertical positional instability so that a passive and active stabilizing system is required. The passive action is performed essentially by the segmented first wall, while the active action is performed by two feedback driven toroidal bars. The performance of such a system is presented here for a reference case, as well as a sensitivity analysis with respect to some parameters

  20. Teaching and Learning Centres: Towards Maturation

    Science.gov (United States)

    Challis, Di; Holt, Dale; Palmer, Stuart

    2009-01-01

    Approximately 70% of Australian Teaching and Learning Centres have been restructured and/or have undergone leadership changes in the last three years. The volatility of this environment reflects the number of significant challenges faced by Teaching and Learning Centres. In determining what makes Centres successful, the issues that are likely to…

  1. Colour centres in barium hexaaluminate (phase I)

    International Nuclear Information System (INIS)

    Colour centres produced by X-ray irradiation of barium hexaaluminate (phase I) with β-alumina structure are studied by electron paramagnetic resonance, optical absorption, and thermally stimulated luminescence. It is shown that in addition to the F+ centres characteristic of β-alumina phases, this compound presents other colour centres such as F, O-, and possibly V-type centres. The stability of these defects is investigated by means of thermal bleaching experiments and thermally stimulated luminescence. An alternative model to the generally accepted one is proposed, for the F+ centres, together with a mechanism of defect formation. (author)

  2. Trade elasticity and vertical specialisation

    OpenAIRE

    Ines Buono; Filippo Vergara Caffarelli

    2013-01-01

    This paper shows that vertical specialisation can increase the elasticity of trade to income, hence explaining dramatic events such as the great trade collapse. We argue that a change in the extent of vertical specialisation affects the elasticity of trade to income, while a mere change in global production levels for a given extent of vertical specialisation does not. In the model we show that only large demand shocks induce firms to vary the extent of vertical specialisation. Using panel da...

  3. Sensing data centres for energy efficiency.

    Science.gov (United States)

    Liu, Jie; Terzis, Andreas

    2012-01-13

    Data centres are large energy consumers today, and their consumption is expected to increase further, driven by the growth in cloud services. The large monetary cost and the environmental impact of this consumption have motivated operators to optimize data centre management. We argue that one of the underlying reasons for the low-energy utilization is the lack of visibility into a data centre's highly dynamic operating conditions. Wireless sensor networks promise to remove this veil of uncertainty by delivering large volumes of data collected at high spatial and temporal fidelities. The paper summarizes data centre operations in order to describe the parameters that a data centre sensing network should collect and motivate the challenges that such a network faces. We present technical approaches for the problems of data collection and management and close with an overview of a data centre genome, an end-to-end data centre sensing system. PMID:22124086

  4. Discussion on 'Centres of excellence' in Africa

    International Nuclear Information System (INIS)

    In Africa, Centres of Excellence should be oriented to build up scientific and technological capacity in the four topics of international Monitoring System related technologies, namely, seismic monitoring, hydro acoustic monitoring, infrasound monitoring and radionuclides monitoring. Training programs on these topics should be a major objective. A network of such centres should be established in a number of African countries. Centres should be equipped with means and materials for on-line course dispatch to interested training centres or research institutions. African centres should develop strong relationship among themselves through information and data exchange and sharing, harmonization of training programs. National data centres may be established as a component of the African Centre of Excellence. States Signatories may authorize the establishment of a specific fund to support the activities of the African center

  5. EHV/HV Underground Cable Systems for Power Transmission

    DEFF Research Database (Denmark)

    Bak, Claus Leth

    Power transmission is facing its largest challenges ever with regards to handling a transition from today’s fossil‐based power production into renewable sources of generation. We can no longer place power plants close to centres of consumption; they must be located where the natural resources are...... to be found. One very good example of this is offshore wind power plants. The current transmission system is laid out in a traditional manner, which is based on the idea of not transporting power over longer distances as the power plants have been located near centres of consumption. It has merely...... layout of the transmission system must be re‐thought in order to accommodate the transmission needs for the future. New lines have to be constructed. Transmission lines are usually laid out as overhead lines, which are large structures, i.e. a 400 kV power pylon is 50 meters high. According to public...

  6. Core Competencies Of A Call Centre AgentCore Competencies Of A Call Centre Agent

    OpenAIRE

    Christine White; Vera Roos

    2005-01-01

    Call centre agents are becoming increasingly important in the call centre context. They act as a contact point between the customer and the company. Call centre agents should have certain competencies to perform their duties sufficiently. Identifying competencies, required to be effective agents, will ease the task of training and recruitment. Due to the interrelatedness of the call centre agent, the management of a call centre and customers, all relevant role players’ perceptions were taken ...

  7. The new AMS control centre

    CERN Multimedia

    Anaïs Schaeffer

    2011-01-01

    Construction work for the future AMS control room began in November 2010 and should be finished this June. The new building, which will have been completed in record time thanks to the professionalism of the project team, will soon be ready to receive the initial data from the AMS experiment.     Luigi Scibile and Michael Poehler, from the GS department, at the AMS control centre construction site.   The Alpha Magnetic Spectrometer (AMS) is due to wing its way towards the International Space Station (ISS) on board the shuttle Discovery in April. Mainly intended for research on antimatter and dark matter, the data collected by AMS will be sent to Houston in the United States and then directly to CERN’s new Building 946. Construction work for the AMS control centre building on the Route Gentner at CERN’s Prévessin site started in November 2010 and must be completed in time to receive the first data from the spectrometer in June. “It normall...

  8. Perceptual centres in speech - an acoustic analysis

    Science.gov (United States)

    Scott, Sophie Kerttu

    Perceptual centres, or P-centres, represent the perceptual moments of occurrence of acoustic signals - the 'beat' of a sound. P-centres underlie the perception and production of rhythm in perceptually regular speech sequences. P-centres have been modelled both in speech and non speech (music) domains. The three aims of this thesis were toatest out current P-centre models to determine which best accounted for the experimental data bto identify a candidate parameter to map P-centres onto (a local approach) as opposed to the previous global models which rely upon the whole signal to determine the P-centre the final aim was to develop a model of P-centre location which could be applied to speech and non speech signals. The first aim was investigated by a series of experiments in which a) speech from different speakers was investigated to determine whether different models could account for variation between speakers b) whether rendering the amplitude time plot of a speech signal affects the P-centre of the signal c) whether increasing the amplitude at the offset of a speech signal alters P-centres in the production and perception of speech. The second aim was carried out by a) manipulating the rise time of different speech signals to determine whether the P-centre was affected, and whether the type of speech sound ramped affected the P-centre shift b) manipulating the rise time and decay time of a synthetic vowel to determine whether the onset alteration was had more affect on P-centre than the offset manipulation c) and whether the duration of a vowel affected the P-centre, if other attributes (amplitude, spectral contents) were held constant. The third aim - modelling P-centres - was based on these results. The Frequency dependent Amplitude Increase Model of P-centre location (FAIM) was developed using a modelling protocol, the APU GammaTone Filterbank and the speech from different speakers. The P-centres of the stimuli corpus were highly predicted by attributes of

  9. GPS, su datum vertical.

    Directory of Open Access Journals (Sweden)

    Esteban Dörries

    2016-03-01

    Full Text Available La introducción de la metodología GPS en aplicaciones topográficas y geodésicas pone en notoria evidencia la clásica separación de sistemas de referencia en horizontal y vertical. Con GPS el posicionamiento es tridimensional, pero el concepto de altura difiere del clásico. Si se desea utilizar la información altimétrica debe contemplarse la ondulación del geoide.

  10. Optimal Control of Vertically Transmitted Disease: An Integrated Approach

    Directory of Open Access Journals (Sweden)

    Samit Bhattacharyya

    2010-01-01

    horizontal transmission, administration of the antiviral drug to infected individuals lessens the chance of vertical transmission. Thus the vaccine and antiviral drug play different roles in controlling the disease, which has both vertical and horizontal transmission. We develop a 3D model with Susceptible–Infected–Recovered under vaccination to the susceptible and antiviral treatment to the infected and consider a control theoretic approach using the Pontryagin maximum principle to analyse the costeffectiveness of the control process. Our results demonstrate that a mixed intervention strategy of vaccination and antiviral drug in a proper ratio is the most effective way to control the disease. We show that cost-effectiveness of both intervention strategies intimately depends on disease-related parameters, such as force of infection, probability of being infected to offspring from infected mothers, loss of immunity or reinfection and also on cost of treatment.

  11. Vertical organic transistors

    International Nuclear Information System (INIS)

    Organic switching devices such as field effect transistors (OFETs) are a key element of future flexible electronic devices. So far, however, a commercial breakthrough has not been achieved because these devices usually lack in switching speed (e.g. for logic applications) and current density (e.g. for display pixel driving). The limited performance is caused by a combination of comparatively low charge carrier mobilities and the large channel length caused by the need for low-cost structuring. Vertical Organic Transistors are a novel technology that has the potential to overcome these limitations of OFETs. Vertical Organic Transistors allow to scale the channel length of organic transistors into the 100 nm regime without cost intensive structuring techniques. Several different approaches have been proposed in literature, which show high output currents, low operation voltages, and comparatively high speed even without sub-μm structuring technologies. In this review, these different approaches are compared and recent progress is highlighted. (topical review)

  12. Centre for nuclear engineering University of Toronto annual report 1984

    International Nuclear Information System (INIS)

    The annual report of the Centre for Nuclear Engineering, University of Toronto covers the following subjects: message from the Dean; Chairman's message; origins of the centre; formation of the centre; new nuclear appointments; and activities of the centre, 1984

  13. Powering the Future Data Centre

    DEFF Research Database (Denmark)

    Zhang, Zhe

    2010-01-01

    . Duty cycle control reduces the circulating current due to the wide input voltage range. With particular transformer windings connection strategy, the proposed boost-type dual input bidirectional converter can draw power from two different dc sources with lower voltage and deliver it to the higher......The extended run Uninterruptible Power Supply system (UPSs) which powered by fuel cells and supercapcitors, is a promising solution for future data centre to obtain environmentfriendly energy efficient and cost effective. There are many challenges in power electronic interface circuits, because of...... the characteristics of these two power sources: long warm-up stage and low dynamics for fuel cell, and variable terminal voltage for supercapacitors. The motivation for this project was to find ways which can overcome those limitations to integrate fuel cells and supercapcitors to the system with high...

  14. Development and Functions of Retail Centres in Zadar

    OpenAIRE

    Martina Jakovčić; Ivica Rendulić

    2008-01-01

    The paper deals with the development of retail centres in Zadar. Types of retail centres are classified on the basis of the type of business outlets and functions. Four main types of retail centres are: shopping centres, hypermarkets, specialized hypermarkets and shopping centres – hypermarkets. Typology based on the location of centres is also developed. Functions of retail centres are analyzed based on the results gathered by a survey conducted in two retail centres, namely City Galleria – ...

  15. Vertical Protocol Composition

    DEFF Research Database (Denmark)

    Groß, Thomas; Mödersheim, Sebastian Alexander

    2011-01-01

    composition, and it is truly commonplace in today’s communication with the diversity of VPNs and secure browser sessions. In fact, it is normal that we have several layers of secure channels: For instance, on top of a VPN-connection, a browser may establish another secure channel (possibly with a different...... end point). Even using the same protocol several times in such a stack of channels is not unusual: An application may very well establish another TLS channel over an established one. We call this selfcomposition. In fact, there is nothing that tells us that all these compositions are sound, i.e., that...... the combination cannot introduce attacks that the individual protocols in isolation do not have. In this work, we prove a composability result in the symbolic model that allows for arbitrary vertical composition (including self-composition). It holds for protocols from any suite of channel and...

  16. SAGE III Meteor-3M L1B Solar Event Transmission Data (HDF-EOS) V004

    Data.gov (United States)

    National Aeronautics and Space Administration — Level 1B pixel group transmission profiles for a single solar event (Suggested Usage: Vertical transmission profiles for input into an inversion algorithm)

  17. SAGE III Meteor-3M L1B Solar Event Transmission Data (HDF-EOS) V003

    Data.gov (United States)

    National Aeronautics and Space Administration — Level 1B pixel group transmission profiles for a single solar event (Suggested Usage: Vertical transmission profiles for input into an inversion algorithm)

  18. Smart work centres in rural areas

    DEFF Research Database (Denmark)

    Lorentzen, Anne Birte

    This paper discusses the establishment of telework centres as an element in local development strategies in rural areas, with a particular view to two new telework centres in region North Denmark. The paper argues that telework centres do not represent an easy solution to problems of local develo...... development and environmental sustainability, and further, that technology may not even be the most important feature needed to make them function as such....

  19. Elm Farm Organic Research Centre December 2006

    OpenAIRE

    Sanders, Richard; Whiltley, Andrew; Haigh, Zoe; Clarke, Sarah; Hitchings, Roger; O'Brien, Josie

    2006-01-01

    The Organic Research Centre. Elm Farm Research Centre Bulletin with Technical Updates from The Organic Advisory Service is a regular publication from The Organic Research Centre. The current issue covers: Report from 2006 Cirencester Conference; Quest for more home produced organic food; in a world where bread matters; Improving wheat with plenty of parents; Unlocking the secrets of the ancient (cereal varieties); Brain food- a good read; Not to late to protect the future: The organic...

  20. Introducing the Centre for Applied Archaeology

    OpenAIRE

    Dominic Perring

    2008-01-01

    The Centre for Applied Archaeology (CAA) is a new research centre within the Institute of Archaeology, established in 2006 to develop the work of the Institute’s Field Archaeology Unit, Archaeology South-East (ASE), through the creation of a productive research environment and the building of links with academic staff members of the Institute. In this article the Director of CAA defines “applied archaeology” and describes the aims and work of the Centre.

  1. Business plan – Tennis centre modernization

    OpenAIRE

    Moravec, Martin

    2012-01-01

    The goal of this master's thesis "Business plan -- Tennis centre modernization" - is creating and writing the business plan for the reconstruction of the existing tennis centre. The theoretical part describes characteristics of small and medium sized enterprises, their meaning. Describes the necessary parts of the business plan, its possible structure. The paper involves the knowledge gained into the concrete case of the tennis centre. Describes its nowadays conditions and possible solutions....

  2. Bangalore looks to new interdisciplinary science centre

    Science.gov (United States)

    Ramachandran, Ramaseshan

    2008-09-01

    A new centre to boost interdisciplinary research in India is being established in Bangalore - India's IT and software capital. The International Centre for Theoretical Sciences (ICTS) will be led by Spenta Wadia, a theoretical physicist from the Tata Institute of Fundamental Research (TIFR) in Mumbai, which is setting up the new centre. He expects construction of the ICTS, the first of its kind in India, to start by November 2009.

  3. Direct Observation of Ultralow Vertical Emittance using a Vertical Undulator

    Energy Technology Data Exchange (ETDEWEB)

    Wootton, Kent

    2015-09-17

    In recent work, the first quantitative measurements of electron beam vertical emittance using a vertical undulator were presented, with particular emphasis given to ultralow vertical emittances [K. P. Wootton, et al., Phys. Rev. ST Accel. Beams, 17, 112802 (2014)]. Using this apparatus, a geometric vertical emittance of 0.9 ± 0.3 pm rad has been observed. A critical analysis is given of measurement approaches that were attempted, with particular emphasis on systematic and statistical uncertainties. The method used is explained, compared to other techniques and the applicability of these results to other scenarios discussed.

  4. ENERGY EFFICIENT REFURBISHMENT IN AUSTRALIAN SHOPPING CENTRES

    OpenAIRE

    Reed, R. G.; S.J. Wilkinson

    2006-01-01

    Retail shopping centres are a dynamic business in Australia, annually generating $51 billion in sales, employing nearly half a million employees and having an asset value of AUD$69 billion. There are 1,338 retail shopping centres in Australia ranging from large regional centres of more than 100,000 square metres of retail space down to smaller, supermarket based centres of around 5,000 square metres. Importantly they account for 28% of the retail space and generate 41% of retail sales (PCA, 2...

  5. Zika and Sexual Transmission

    Science.gov (United States)

    ... Address What's this? Submit What's this? Submit Button Zika and Sexual Transmission Language: English Español Português ... Healthcare Providers: Sexual Transmission of Zika Basics of Zika Virus and Sex Transmission Zika can be passed ...

  6. Internal wave transmission through a thermohaline staircase

    Science.gov (United States)

    Sutherland, Bruce R.

    2016-05-01

    With the aim to predict energy transport by internal waves incident upon observed density staircases in the ocean, the theory for internal wave tunneling through a single finite-size mixed region is extended to predict the transmission of internal waves through a piecewise-constant density profile with an arbitrary number of steps. An analytic solution is found if all steps have equal vertical extent. From this solution, bounds are established for the relative incident horizontal wave number and frequency of waves that have negligible transmission, a result that is independent of the number of steps. If the step sizes vary randomly about a mean vertical extent, the transmission can be computed numerically for several random realizations. Provided the horizontal wavelength is much longer than the total vertical extent of the staircase, the standard deviation of the computed transmission coefficients is small and the mean agrees well with the analytic prediction for equally spaced steps. The results are applied to thermohaline staircases observed in the ocean in order to put lower bounds on the wavelengths of long inertia gravity waves that significantly transmit to great depth.

  7. Latitude and longitude vertical disparity

    OpenAIRE

    Read, Jenny C. A.; Phillipson, Graeme P.; Glennerster, Andrew

    2009-01-01

    The literature on vertical disparity is complicated by the fact that several different definitions of the term “vertical disparity” are in common use, often without a clear statement about which is intended or a widespread appreciation of the properties of the different definitions. Here, we examine two definitions of retinal vertical disparity: elevation-latitude and elevation-longitude disparity. Near the fixation point, these definitions become equivalent, but in general, they have quite d...

  8. Latitude and longitude vertical disparities

    OpenAIRE

    Read, Jenny C. A.; Phillipson, Graeme P.; Glennerster, Andrew

    2009-01-01

    The literature on vertical disparity is complicated by the fact that several different definitions of the term “vertical disparity” are in common use, often without a clear statement about which is intended or a widespread appreciation of the properties of the different definitions. Here, we examine two definitions of retinal vertical disparity: elevation-latitude and elevation-longitude disparities. Near the fixation point, these definitions become equivalent, but in general, they have quite...

  9. Survey of Transmission Cost Allocation Methodologies for Regional Transmission Organizations

    Energy Technology Data Exchange (ETDEWEB)

    Fink, S.; Porter, K.; Mudd, C.; Rogers, J.

    2011-02-01

    The report presents transmission cost allocation methodologies for reliability transmission projects, generation interconnection, and economic transmission projects for all Regional Transmission Organizations.

  10. Fast Web-Based Data Transmission

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Since web-based GIS processes large-size spatial geographic information on internet, we should try to improve the efficiency of spatial data query processing and transmission. This paper presents two efficient methods for this purpose: division-transmission and progressive-transmission methods. In division-transmission method, a map can be divided into several parts, called “tiles”, and only tiles can be transmitted at the request of a client. In progressive-transmission method, a map can be split into several phase views based on the significance of vertices, and a server produces a target object and then transmits it progressively when this spatial object is requested from a client. In order to achieve these methods, the algorithms, “tile division”, “priority-order estimation” and the strategies for data transmission are proposed in this paper, respectively. Compared with such traditional methods as “map total transmission” and “layer transmission”, the web-based GIS data transmission, proposed in this paper, is advantageous in the increase of the data transmission efficiency by a great margin.

  11. Laparoscopic adrenalectomy: Single centre experience.

    LENUS (Irish Health Repository)

    O'Farrell, N J

    2012-02-01

    BACKGROUND: Laparoscopic adrenalectomy is an attractive alternative to the traditional open approach in the surgical excision of an adrenal gland. It has replaced open adrenalectomy in our institution and we review our experience to date. METHODS: All cases of laparoscopic adrenalectomies in our hospital over eight years (from 2001 to May 2009) were retrospectively reviewed. Patient demographics, diagnosis, length of hospital stay, histology and all operative and post-operative details were evaluated. RESULTS: Fifty-five laparoscopic adrenalectomies (LA) were performed on 51 patients over eight years. The mean age was 48 years (Range 16-86 years) with the male: female ratio 1:2. Twenty-three cases had a right adrenalectomy, 24 had a left adrenalectomy and the remaining four patients had bilateral adrenalectomies. 91% were successfully completed laparoscopically with five converted to an open approach. Adenomas (functional and non functional) were the leading indication for LA, followed by phaeochromocytomas. Other indications for LA included Cushing\\'s disease, adrenal malignancies and rarer pathologies. There was one mortality from necrotising pancreatitis following a left adrenalectomy for severe Cushing\\'s disease, with subsequent death 10 days later. CONCLUSION: Laparoscopic adrenalectomy is effective for the treatment of adrenal tumours, fulfilling the criteria for the ideal minimally invasive procedure. It has replaced the traditional open approach in our centre and is a safe and effective alternative. However, in the case of severe Cushing\\'s disease, laparoscopic adrenalectomy has the potential for significant adverse outcomes and mortality.

  12. Vertically reciprocating auger

    Science.gov (United States)

    Etheridge, Mark; Morgan, Scott; Fain, Robert; Pearson, Jonathan; Weldi, Kevin; Woodrough, Stephen B., Jr.

    1988-01-01

    The mathematical model and test results developed for the Vertically Reciprocating Auger (VRA) are summarized. The VRA is a device capable of transporting cuttings that result from below surface drilling. It was developed chiefly for the lunar surface, where conventional fluid flushing while drilling would not be practical. The VRA uses only reciprocating motion and transports material through reflections with the surface above. Particles are reflected forward and land ahead of radially placed fences, which prevent the particles from rolling back down the auger. Three input wave forms are considered to drive the auger. A modified sawtooth wave form was chosen for testing, over a modified square wave or sine wave, due to its simplicity and effectiveness. The three-dimensional mathematical model predicted a sand throughput rate of 0.2667 pounds/stroke, while the actual test setup transported 0.075 pounds/stroke. Based on this result, a correction factor of 0.281 is suggested for a modified sawtooth input.

  13. Vertical 2D Heterostructures

    Science.gov (United States)

    Lotsch, Bettina V.

    2015-07-01

    Graphene's legacy has become an integral part of today's condensed matter science and has equipped a whole generation of scientists with an armory of concepts and techniques that open up new perspectives for the postgraphene area. In particular, the judicious combination of 2D building blocks into vertical heterostructures has recently been identified as a promising route to rationally engineer complex multilayer systems and artificial solids with intriguing properties. The present review highlights recent developments in the rapidly emerging field of 2D nanoarchitectonics from a materials chemistry perspective, with a focus on the types of heterostructures available, their assembly strategies, and their emerging properties. This overview is intended to bridge the gap between two major—yet largely disjunct—developments in 2D heterostructures, which are firmly rooted in solid-state chemistry or physics. Although the underlying types of heterostructures differ with respect to their dimensions, layer alignment, and interfacial quality, there is common ground, and future synergies between the various assembly strategies are to be expected.

  14. Vertical separation for TCF

    International Nuclear Information System (INIS)

    The authors studied an insertion for electrostatic separation of the electron and positron beams with the aims of: increasing luminosity by decreasing the minimum bunch spacing, matching the vertical dispersion function (not done in the Jowett lattice). The authors looked at three possibilities for the start of the insertion: a quadrupole doublet followed by the electrostatic separator (Jowett), a quadrupole doublet with the electrostatic separator between the two quadrupoles (Kamada), a separator followed by a quadrupole doublet. The third possibility was immediately discharged. Although possible for a B-factor with magnetic separation it is impractical for use with electrostatic separation because of the length and cross section of separator required. The Kamada scheme looked promising for getting very short inter-bunch spacing, but suffered from the disadvantage of requiring a very large ratio of beta functions at the Interaction Point (IP) (βx*/βy* = 100). (They would rather have a β* ratio closer to 20 to 1). They decided to persue the doublet scheme to see whether it could match the performance of Kamada insertion. They assumed superconducting magnets could be used for the insertion quadrupoles, and they used as strong an electrostatic field for the separator as Kamada

  15. Vertical guidance of shearers

    International Nuclear Information System (INIS)

    Mining Engineers have always been aware of the basic need to avoid contamination of the mined product, by controlling the cutting horizon at the coal face. The ability to maintain the optimum cutting horizon results in more effective roof control and ensures a safer and more efficient working environment, for men and machinery. The cost of treatment in the surface coal preparation plant is reduced. Transportation through the total mine system of material finally destined for the spoil heap is minimised. A reduction in product contamination is achieved and makes more effective use of the mine capacity. These benefits make possible significant improvements in productivity and financial returns. Exploitation of micro computer based systems has enabled the successful development of equipment which employs sensors to detect the very low natural gamma radiation from roof strata; to determine and allow control of the position of the cut relative to the roof and floor. This paper reviews the experience gained by the National Coal Board, particularly in South Yorkshire Area, with the vertical steering of ranging drum shearers. It outlines the benefits and considers the future for this technology and its contribution to total coal face automation

  16. Oil Trading Centre to Reopen in Shanghai

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    @@ Chinese oil companies will likely resume activities at the oil trading centre in Shanghai this year, a move to further liberalize the once tightly controlled oil market. The centre will trade forward contracts for refined oil products,including gasoline, diesel oil, kerosene and fuel oil, industrial sources said.

  17. Neighbourhood Centres – Organisation, Management and Finance

    DEFF Research Database (Denmark)

    Larsen, Jacob Norvig

    From the late 1990s neighbourhood centres were brought to the fore of public urban regen-eration policy, because they were seen as a means to accelerate the formation of social capital in deprived urban neighbourhoods. A number of such local community centres were established with substantial pub...

  18. Safety strategy at the RACSO nuclear centre

    International Nuclear Information System (INIS)

    The paper describes in general terms the physical security situation at the RACSO nuclear centre and the principal measures adopted to deal with the risk of subversive activities. Since 1980, Peru had to face terrorist problems; therefore, measures were adopted at RACSO to deal with this risk. As a result, it has been possible to keep the nuclear centre free from terrorist attacks. (author)

  19. Modern Equipment at VATESI Emergency Response Centre

    International Nuclear Information System (INIS)

    The Emergency Response Centre of the State Nuclear Power Safety Inspectorate equipped with state-of-the-art instruments started operating. The Centre is fulfilling the functions prescribed by the Lithuanian legislation in case of an accident at the Ignalina NPP, as well as nuclear or radiation accidents in the neighboring countries in accordance with the Convention on Early Notification

  20. Communications strategy for the Chernobyl Centre

    International Nuclear Information System (INIS)

    This Communications Strategy was developed for the International Chernobyl Centre (ICC) as part of a joint UK/Ukraine project, sponsored by the Department of Trade and Industry and NNC Limited. The Plan was developed during four weeks of workshop discussions in the UK between staff from the centre and experienced PR Professionals from NNC Limited. The requirements for a sustained communications activity at the ICC go much further than simply enhancing or promoting the Centre's scientific and technical activities. Raising sufficient awareness of the Centre among potential funding agents and commercial partners is critical to its future development as a major centre for international co-operation and research. It is only through establishing and developing effective communications that the Centre will become well enough known and understood both within the Ukraine, and internationally, to secure its long term future. However, as the workshop programme unfolded, it also became clear that communications was in itself a legitimate and necessary function of the Centre, and part of the foundations of its existence. The Centre has a fundamental role as an 'information exchange', collecting and communicating information from within the Ukraine to the rest of the world, and interpreting world interest and attitudes to the Ukraine Government and nuclear industry. As such compliments the efforts of individual power plant and corporate PR functions within the Ukraine nuclear energy sector

  1. CMS Centres Worldwide a New Collaborative Infrastructure

    CERN Document Server

    Taylor, Lucas

    2009-01-01

    The CMS Experiment at the LHC is establishing a global network of inter-connected "CMS Centres" for controls, operations and monitoring. These support: (1) CMS data quality monitoring, detector calibrations, and analysis; and (2) computing operations for the processing, storage and distribution of CMS data. We describe the infrastructure, computing, software, and communications systems required to create an effective and affordable CMS Centre. We present our highly successful operations experiences with the major CMS Centres at CERN, Fermilab, and DESY during the LHC first beam data-taking and cosmic ray commissioning work. The status of the various centres already operating or under construction in Asia, Europe, Russia, South America, and the USA is also described. We emphasise the collaborative communications aspects. For example, virtual co-location of experts in CMS Centres Worldwide is achieved using high-quality permanently-running "telepresence" video links. Generic Web-based tools have been developed ...

  2. The role of the sexual assault centre.

    LENUS (Irish Health Repository)

    Eogan, Maeve

    2013-02-01

    Sexual Assault Centres provide multidisciplinary care for men and women who have experienced sexual crime. These centres enable provision of medical, forensic, psychological support and follow-up care, even if patients chose not to report the incident to the police service. Sexual Support Centres need to provide a ring-fenced, forensically clean environment. They need to be appropriately staffed and available 24 hours a day, 7 days a week to allow prompt provision of medical and supportive care and collection of forensic evidence. Sexual Assault Centres work best within the context of a core agreed model of care, which includes defined multi-agency guidelines and care pathways, close links with forensic science and police services, and designated and sustainable funding arrangements. Additionally, Sexual Assault Centres also participate in patient, staff and community education and risk reduction. Furthermore, they contribute to the development, evaluation and implementation of national strategies on domestic, sexual and gender-based violence.

  3. Design and static performance of high speed machining centre with "direct drive"

    Institute of Scientific and Technical Information of China (English)

    Shuhong XIAO; Yulian CHEN; Guangyuan ZHENG

    2009-01-01

    "Direct drive" is an ideal method for speeding machine tools. In the structure of a CNC machining centre with "direct drive", the linear motor's primary and secondary parts are assembled into the worktable and machine bed respectively to directly drive the worktable. The built-in rotary motor is assembled in the spindle to realize the main transmission system of the machine tool "direct drive". All mechanical transmission elements in machine tools are eliminated. High speed, efficiency, and accuracy are easily obtained. However, in this type of "direct drive" machining centre, the magnetic attraction force between the primary and the secondary linear motors and the dynamic impact at acceleration and deceleration are directly imposed on the machine tool, and influence the performance of the machining centre. This paper analyzes the special demands of "direct drive" on the machine centre, and introduces a new structure of the machining tool. The worktable and machine bed are optimized to meet the special demands of "direct drive". Static performance simulation on the machining centre is done to reveal an ideal result.

  4. Analytical basis of technology asymmetrical allocation of cargo masses common centre in wagons

    Directory of Open Access Journals (Sweden)

    Khabibulla TURANOV

    2009-01-01

    Full Text Available The article gives the account of results of the analytical basis of technology asymmetrical cargo allocation in a wagon during rolling stock movement on track unevenness waves. The finite analytical formulas have been obtained for determination of response of wagon bogie spring sets in case of simultaneous displacement of cargo masses common centre longitudinally and sideways to the wagon, which make it possible to ground the cargo allocation according to admissible value of wagon vertical dynamic addition coefficient.

  5. The Canadian Astronomy Data Centre

    Science.gov (United States)

    Ball, Nicholas M.; Schade, D.; Astronomy Data Centre, Canadian

    2011-01-01

    The Canadian Astronomy Data Centre (CADC) is the world's largest astronomical data center, holding over 0.5 Petabytes of information, and serving nearly 3000 astronomers worldwide. Its current data collections include BLAST, CFHT, CGPS, FUSE, Gemini, HST, JCMT, MACHO, MOST, and numerous other archives and services. It provides extensive data archiving, curation, and processing expertise, via projects such as MegaPipe, and enables substantial day-to-day collaboration between resident astronomers and computer specialists. It is a stable, powerful, persistent, and properly supported environment for the storage and processing of large volumes of data, a condition that is now absolutely vital for their science potential to be exploited by the community. Through initiatives such as the Common Archive Observation Model (CAOM), the Canadian Virtual Observatory (CVO), and the Canadian Advanced Network for Astronomical Research (CANFAR), the CADC is at the global forefront of advancing astronomical research through improved data services. The CAOM aims to provide homogeneous data access, and hence viable interoperability between a potentially unlimited number of different data collections, at many wavelengths. It is active in the definition of numerous emerging standards within the International Virtual Observatory, and several datasets are already available. The CANFAR project is an initiative to make cloud computing for storage and data-intensive processing available to the community. It does this via a Virtual Machine environment that is equivalent to managing a local desktop. Several groups are already processing science data. CADC is also at the forefront of advanced astronomical data analysis, driven by the science requirements of astronomers both locally and further afield. The emergence of 'Astroinformatics' promises to provide not only utility items like object classifications, but to directly enable new science by accessing previously undiscovered or intractable

  6. IDRANAP - European Centre of Excellence

    International Nuclear Information System (INIS)

    Selected by the European Commission (EC) experts out of 185 proposals from 11 countries, IDRANAP (Inter-Disciplinary Research and Applications based on Nuclear and Atomic Physics) is the only EC Centre of Excellence in nuclear physics. The project, initiated and developed by a remarkable team from our institute, researchers with a recognized international scientific level, has as main objectives: - promotion in Romania and in the region of modern applications derived from basic and applied research in nuclear and atomic physics; - disciplinary research in ecology, health, biology, science of materials; - specific nuclear and atomic physics research aimed to open new possibilities for applications; - to ensure stimulative conditions for PhD students from Romania and other EC candidate countries to improve their knowledge and experience by joining scientific activities in the region, a fact that might counteract their tendency to migrate to Western countries. The high scientific level of researchers, their access to national and international facilities as well as the link with prestigious laboratories abroad and the socio-economic demand motivated the development of the project. Among expected results, we mention: improving and spreading the scientific knowledge by publications; producing new facilities, devices and instruments; application of nuclear methods in industry, health-care and environment protection, and training of young researchers. The project consists of 18 workpackages structured in 5 distinct areas: - Determining environmental pollution; - Nuclear methods in biology and medicine; - Radionuclide metrology; - Analysis and characterization of materials; - Nuclei far from stability, decay modes, cosmic rays, and facilities.We make an up-to-date presentation of obtained results and activities performed within IDRANAP project, as well as a short overview of our institute. (author)

  7. Big Surveys, Big Data Centres

    Science.gov (United States)

    Schade, D.

    2016-06-01

    Well-designed astronomical surveys are powerful and have consistently been keystones of scientific progress. The Byurakan Surveys using a Schmidt telescope with an objective prism produced a list of about 3000 UV-excess Markarian galaxies but these objects have stimulated an enormous amount of further study and appear in over 16,000 publications. The CFHT Legacy Surveys used a wide-field imager to cover thousands of square degrees and those surveys are mentioned in over 1100 publications since 2002. Both ground and space-based astronomy have been increasing their investments in survey work. Survey instrumentation strives toward fair samples and large sky coverage and therefore strives to produce massive datasets. Thus we are faced with the "big data" problem in astronomy. Survey datasets require specialized approaches to data management. Big data places additional challenging requirements for data management. If the term "big data" is defined as data collections that are too large to move then there are profound implications for the infrastructure that supports big data science. The current model of data centres is obsolete. In the era of big data the central problem is how to create architectures that effectively manage the relationship between data collections, networks, processing capabilities, and software, given the science requirements of the projects that need to be executed. A stand alone data silo cannot support big data science. I'll describe the current efforts of the Canadian community to deal with this situation and our successes and failures. I'll talk about how we are planning in the next decade to try to create a workable and adaptable solution to support big data science.

  8. Smart Transmission Grids - Benefits and Risks

    Directory of Open Access Journals (Sweden)

    Velasco-Ramírez E.

    2013-01-01

    Full Text Available Nowadays the Power Systems are working near their stability limits, for this reason it is necessary and essential a transition to new transmission systems that ensure efficient delivery of electrical energy, with the objective to prevent “blackouts” that causesignificant losses in the economy of any country in the world. This paper analyzes important elements to consider having a healthy and efficient transition from a power grid vertically integrated into a smart transmission grid. A comparative analysis in the model, development, benefits and risks of the implementation of these systems, between two of the main marc of references of smart grids, the EU and the USA is presented.

  9. Vibration Isolation and Transmissibility Characteristics of Passive Sequential Damper

    Directory of Open Access Journals (Sweden)

    M.S. Patil

    2004-01-01

    Full Text Available This paper presents a half-car model (4-degrees-of-freedom employing nonlinear passlve sequential damper. The vibration isolation and transmrssibility effect on the vehicle's centre ofgravity (C.G. has been studied. The results have been compared for transmissibility, displacement, and velocity transient response for half-car model having nonlinear passive sequentialhydropneumatic damper under different terrain excitation.

  10. Clustering of serotypes in a longitudinal study of Streptococcus pneumoniae carriage in three day care centres

    Directory of Open Access Journals (Sweden)

    Tanskanen Antti

    2008-12-01

    Full Text Available Abstract Background Streptococcus pneumoniae (pneumococcus causes a wide range of clinical manifestations that together constitute a major burden of disease worldwide. The main route of pneumococcal transmission is through asymptomatic colonisation of the nasopharynx. Studies of transmission are currently of general interest because of the impact of the new conjugate-polysaccharide vaccines on nasopharyngeal colonisation (carriage. Here we report the first longitudinal study of pneumococcal carriage that records serotype specific exposure to pneumococci simultaneously within the two most important mixing groups, families and day care facilities. Methods We followed attendees (N = 59 with their family members (N = 117 and the employees (N = 37 in three Finnish day care centres for 9 months with monthly sampling of nasopharyngeal carriage. Pneumococci were cultured, identified and serotyped by standard methods. Results Children in day care constitute a core group of pneumococcal carriage: of the 36 acquisitions of carriage with documented exposure to homologous pneumococci, the attendee had been exposed in her/his day care centre in 35 cases and in the family in 9 cases. Day care children introduce pneumococci to the family: 66% of acquisitions of a new serotype in a family were associated with simultaneous or previous carriage of the same type in the child attending day care. Consequently, pneumococcal transmission was found to take place as micro-epidemics driven by the day care centres. Each of the three day care centres was dominated by a serotype of its own, accounting for 100% of the isolates of that serotype among all samples from the day care attendees. Conclusion The transmission of pneumococci is more intense within than across clusters defined by day care facilities. The ensuing micro-epidemic behaviour enhances pneumococcal transmission.

  11. Clustering of serotypes in a longitudinal study of Streptococcus pneumoniae carriage in three day care centres

    Science.gov (United States)

    Leino, Tuija; Hoti, Fabian; Syrjänen, Ritva; Tanskanen, Antti; Auranen, Kari

    2008-01-01

    Background Streptococcus pneumoniae (pneumococcus) causes a wide range of clinical manifestations that together constitute a major burden of disease worldwide. The main route of pneumococcal transmission is through asymptomatic colonisation of the nasopharynx. Studies of transmission are currently of general interest because of the impact of the new conjugate-polysaccharide vaccines on nasopharyngeal colonisation (carriage). Here we report the first longitudinal study of pneumococcal carriage that records serotype specific exposure to pneumococci simultaneously within the two most important mixing groups, families and day care facilities. Methods We followed attendees (N = 59) with their family members (N = 117) and the employees (N = 37) in three Finnish day care centres for 9 months with monthly sampling of nasopharyngeal carriage. Pneumococci were cultured, identified and serotyped by standard methods. Results Children in day care constitute a core group of pneumococcal carriage: of the 36 acquisitions of carriage with documented exposure to homologous pneumococci, the attendee had been exposed in her/his day care centre in 35 cases and in the family in 9 cases. Day care children introduce pneumococci to the family: 66% of acquisitions of a new serotype in a family were associated with simultaneous or previous carriage of the same type in the child attending day care. Consequently, pneumococcal transmission was found to take place as micro-epidemics driven by the day care centres. Each of the three day care centres was dominated by a serotype of its own, accounting for 100% of the isolates of that serotype among all samples from the day care attendees. Conclusion The transmission of pneumococci is more intense within than across clusters defined by day care facilities. The ensuing micro-epidemic behaviour enhances pneumococcal transmission. PMID:19116005

  12. Nuclear Power Plant Temelin Technical Support Centre

    International Nuclear Information System (INIS)

    The erection of the Technical Support Centre for the Nuclear Power Plant Temelin has been a relatively sophisticated and costly issue. It was by proper use of the existing systems, as e.g. I and C, ISE and other systems, that a robust system has been created that is able to meet any requirements laid on the performance of the Technical Support Centre. The decision of the utility CEZ, a.s. that made it possible to establish the Technical Support Centre at the Nuclear Power Plant Temelin has been a right step which shows the level of safety culture within the utility. (author)

  13. Review of CERN Data Centre Infrastructure

    Science.gov (United States)

    Andrade, P.; Bell, T.; van Eldik, J.; McCance, G.; Panzer-Steindel, B.; Coelho dos Santos, M.; Traylen and, S.; Schwickerath, U.

    2012-12-01

    The CERN Data Centre is reviewing strategies for optimizing the use of the existing infrastructure and expanding to a new data centre by studying how other large sites are being operated. Over the past six months, CERN has been investigating modern and widely-used tools and procedures used for virtualisation, clouds and fabric management in order to reduce operational effort, increase agility and support unattended remote data centres. This paper gives the details on the project's motivations, current status and areas for future investigation.

  14. Red luminescence of color centres in sapphire

    International Nuclear Information System (INIS)

    Spectral and polarization studies of the IR photoluminescence of neutron-irradiated sapphire crystals are presented aimed at the clarification of the luminescence centres and the involved electronic transitions. From the temperature dependence of the photoluminescence bands the existence of a potential barrier for the transition from the highest to the lowest excited state of the axial centre was deduced and the height of the barrier was estimated. For a luminescence centre involving a pair of oxygen vacancies with three located electrons a semiquantitative configuration - coordinate diagram is constructed and discussed

  15. Review of CERN Data Centre Infrastructure

    CERN Document Server

    Andrade, P; van Eldik, J; McCance, G; Panzer-Steindel, B; Coelho dos Santos, M; Traylen, S; Schwickerath, U

    2012-01-01

    The CERN Data Centre is reviewing strategies for optimizing the use of the existing infrastructure and expanding to a new data centre by studying how other large sites are being operated. Over the past six months, CERN has been investigating modern and widely-used tools and procedures used for virtualisation, clouds and fabric management in order to reduce operational effort, increase agility and support unattended remote data centres. This paper gives the details on the project’s motivations, current status and areas for future investigation.

  16. Vertical Collective Action: Addressing Vertical Asymmetries in Watershed Management

    OpenAIRE

    Cárdenas, Juan-Camilo; Rodriguez, Luz Angela; Johnson, Nancy

    2015-01-01

    Watersheds and irrigation systems have the characteristic of connecting people vertically by water flows. The location of users along these systems defines their role in the provision and appropriation of water which adds complexity to the potential for cooperation. Verticality thus imposes a challenge to collective action. This paper presents the results of field experiments conducted in four watersheds of Colombia (South America) and Kenya (East Africa) to study the role that location plays...

  17. Towards Human-Centred Design

    Science.gov (United States)

    Bannon, Liam J.

    The field of HCI has evolved and expanded dramatically since its origin in the early 1980’s. The HCI community embraces a large community of researchers and practitioners around the world, from a variety of disciplinary backgrounds in the human and social sciences, engineering and informatics, and more recently, the arts and design disciplines. This kaleidoscope of cultures and disciplines as seen at INTERACT Conferences provides a rich pool of resources for examining our field. Applications are increasingly exploring our full range of sensory modalities, and merging the digital and physical worlds. WiFi has opened up a huge design space for mobile applications. A focus on usability of products and services has been complemented by an emphasis on engagement, enjoyment and experience. With the advent of ubiquitous computing, and the emergence of “The Internet of Things”, new kinds of more open infrastructures make possible radically new kinds of applications. The sources of innovation have also broadened, to include human and social actors outside of the computing and design organizations. The question is to what extent is our mainstream thinking in the HCI field ready for the challenges of this Brave New World? Do the technological and social innovations that we see emerging require us to re-shape, or even, re-create, our field, or is it a case of a more gradual evolution and development of that which we already know? In this closing Keynote, I will provide a perspective on the evolution and development of the HCI field, looking backwards as well as forwards, in order to determine what are some of the changes of significance in the field. This “broad-brush” approach to what I term “ human-centred design” will be complemented by the examination of specific projects and applications, to help anchor some of the discussion. Areas such as user-centred design, participatory design, computer-supported cooperative work and learning, and interaction design, in

  18. Potential vorticity dynamics in the Canadian Climate Centre GCM

    International Nuclear Information System (INIS)

    The global distribution of Ertel potential vorticity (PV), simulated by the Canadian Climate Centre general circulation model (CCC GCM) is examined. An expression for PV in terms of an arbitrary vertical coordinate is formulated. This expression is used to calculate temporally averaged PV from the model temperature and wind fields. It is shown that a good approximation to the temporally averaged PV can be obtained from temporally averaged temperature and wind fields. An equation governing the time evolution of PV in the model vertical coordinate system is also derived. This equation is written in flux form and the associated flux is examined in a lower stratographic region of enhanced gravity-wave drag, above the Tibetan plateau. In this region, the southward transport of PV effected by gravity-wave drag is balanced to a large degree by the advection of PV northward. Finally, results from a recent experimental version of the CCC GCM, with an uppermost level at 1 mb, are used to examine PV dynamics associated with a spontaneous model stratospheric sudden warming. The warming is preceded by 2 successive large amplitude wavenumber 1 disturbances in the lower stratosphere. The second of these leads to splitting of the mid-stratospheric vortex into a double vortex pattern, as is clearly evident on maps of the 850K PV field during the warming period

  19. Symmetric centres of braided monoidal categories

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    This paper introduces the concept of‘symmetric centres' of braided monoidal categories. Let H be a Hopf algebra with bijective antipode over a field k. We address the symmetric centre of the Yetter-Drinfel'd module category HH(yD) and show that a left Yetter-Drinfel'd module M belongs to the symmetric centre of HH(yD) if and only if M is trivial. We also study the symmetric centres of categories of representations of quasitriangular Hopf algebras and give a sufficient and necessary condition for the braid of H(M) to induce the braid of (H(H)(A),(○)A,A,φ,l,r), or equivalently, the braid of (A#H(H),(○)A,A,φ,l,r), where A is a quantum commutative H-module algebra.

  20. The Manche storage centre: Annual report 2010

    International Nuclear Information System (INIS)

    This report presents the installations of the CSM (Centre de Stockage de la Manche), the first French centre for the surface storage of low and intermediate level radioactive wastes. It briefly describes the site and its buildings, the multi-layer principle which is used to cover the wastes, how surface and drainage waters are managed, which controls are performed. It presents the different nuclear safety measures: principles, prevention measures, technical measures to meet the requirements, the legal plan for the control of the Centre and its environment, the quality management organization. It presents the measures regarding radioprotection and safety, indicates incidents and accidents which occurred in 2010, gives information and data on release management (effluents, controls, obtained data on surface and underground waters in different points). It briefly comments how the Centre's wastes are managed, evokes the case of other pollutions, and indicates actions performed in terms of public information

  1. The nuclear research centre at Bariloche, Argentina

    International Nuclear Information System (INIS)

    The nuclear research centre at Bariloche (CAB) is one of the four centres under the Atomic Energy Commission of Argentina (CNEA). The research programme of CAB addresses various issues like nuclear reactor development, nuclear fuel and fuel cycle, applications of radioisotopes and radiation, and waste management. There is also a basic nuclear science component. The human resource development in the areas of physics and nuclear engineering is done in an associated Balseiro Institute which has undergraduate and graduate programmes as well as doctoral and postdoctoral research. The Centre interacts well with the society and provides services in the nuclear area. It has a close interaction with the nuclear sector of Argentina as also with many international organisations. Regulatory control over the Centre is carried out by the Nuclear Regulatory Authority of Argentina. (author)

  2. Health centre surveys as a potential tool for monitoring malaria epidemiology by area and over time.

    Directory of Open Access Journals (Sweden)

    Abraham R Oduro

    Full Text Available BACKGROUND: Presently, many malaria control programmes use health facility data to evaluate the impact of their interventions. Facility-based malaria data, although useful, have problems with completeness, validity and representativeness and reliance on routinely collected health facility data might undermine demonstration of the magnitude of the impact of the recent scaleups of malaria interventions. To determine whether carefully conducted health centre surveys can be reliable means of monitoring area specific malaria epidemiology, we have compared malaria specific indices obtained from surveys in health centres with indices obtained from cross-sectional surveys conducted in their catchment communities. METHODS: A series of age stratified, seasonal, cross-sectional surveys were conducted during the peak malaria transmission season in 2008 and during the following dry season in 2009 in six ecologically diverse areas in The Gambia. Participants were patients who attended the health centres plus a representative sample from the catchment villages of these health facilities. Parasitaemia, anaemia, attributable proportion of fever and anti-MSP1-(19 antibody seroprevalence were compared in the health facility attendees and community participants. RESULTS: A total of 16,230 subjects completed the study; approximately half participated in the health centre surveys and half in the wet season surveys. Data from both the health centre and community surveys showed that malaria endemicity in The Gambia is now low, heterogeneous and seasonal. In the wet season, parasitaemia, seroprevalence and fever prevalence were higher in subjects seen in the health centres than in the community surveys. Age patterns of parasitaemia, attributable proportions of fever and seroprevalence rates were similar in subjects who participated in the community and health centre surveys. CONCLUSION: Health centre surveys have potential as a surveillance tool for evaluating area

  3. Analytical computation of reflection and transmission coefficients for love waves

    International Nuclear Information System (INIS)

    The computation of the transmission and reflection coefficients is an important step in the construction, if modal summation technique is used, of synthetic seismograms for 2-D or 3-D media. These coupling coefficients for Love waves at a vertical discontinuity are computed analytically. Numerical test for realistic structures show how the energy carried by an incoming mode is redistributed on the various modes existing on both sides of the vertical interface. (author). 15 refs, 8 figs

  4. Vertical axis wind turbine airfoil

    Science.gov (United States)

    Krivcov, Vladimir; Krivospitski, Vladimir; Maksimov, Vasili; Halstead, Richard; Grahov, Jurij Vasiljevich

    2012-12-18

    A vertical axis wind turbine airfoil is described. The wind turbine airfoil can include a leading edge, a trailing edge, an upper curved surface, a lower curved surface, and a centerline running between the upper surface and the lower surface and from the leading edge to the trailing edge. The airfoil can be configured so that the distance between the centerline and the upper surface is the same as the distance between the centerline and the lower surface at all points along the length of the airfoil. A plurality of such airfoils can be included in a vertical axis wind turbine. These airfoils can be vertically disposed and can rotate about a vertical axis.

  5. Deloitte Global Immigration Service Centre -- Business Plan

    OpenAIRE

    Mejtský, Miroslav

    2013-01-01

    The thesis "Deloitte Global Immigration Service Centre -- Business Plan" is in the theoretical part focused on the aspects of the business plan as a document, the ways of its evaluation and financing business in general. The practical part is focused on creation of a business plan for a project of Global Immigration Service Centre with all the essentials in order to verify the feasibility of the project. The project seems feasible for implementation based on the results of the thesis.

  6. Nuclear research centres - The Egyptian experiment

    International Nuclear Information System (INIS)

    The Atomic Energy Authority of Egypt has four research centres located at two sites. Its research reactors are devoted to the production of isotopes, neutron beam experiments, activation analysis and materials research. The accelerators are devoted to the production of short lived isotopes for medical applications and materials R and D. Irradiation technology is used for sterilization of medical supplies and food preservation. High level of expertise in those centres is also useful for other developmental activities in Egypt. (author)

  7. Karlsruhe Nuclear Research Centre. Programme budget 1988

    International Nuclear Information System (INIS)

    Following a general survey of tasks, planned activities and developmental trends of the nuclear research centre, the report gives an account of the activities to be performed in the subject fields of main interest, showing the budgeting figures for annual expenditure (for personnel, investments, operating costs) up to the year 1991. Further information explains the infrastructure of the centre and the distribution of overall expenditure as well as the budgetary planning. (UA)

  8. INFOTERM – Information Disseminating Centre for Terminology

    OpenAIRE

    Albina Auksoriūtė

    2014-01-01

    International Information Centre for Terminology (INFOTERM) was founded in 1971 by contract with the United Nations Educational, Scientific and Cultural Organization (UNESCO) and the Austrian Standards Institute (ASI). In 1996, INFOTERM was reorganized and established as an independent non-profit organization. INFOTERM promotes and supports the cooperation of existing and the establishment of new terminology centres and networks with the general aim to improve domain communication, knowledge ...

  9. Joint Research Centre. Ispra establishment-Italy

    International Nuclear Information System (INIS)

    A comprehensive review of the work carried out during 1974 and 1975 in the Ispra establishment of the Joint Research Centre is presented. A description of the activity carried out within the context of the running programmes is given. Some of the most relevant scientific and technical achievement are described from the viewpoints of the Scientific Departments of the Centre. The technical and administrative support activities are also presented. A list of publications issued by the Ispra Scientific staff is given

  10. Two centre problems in relativistic atomic physics

    OpenAIRE

    McConnell, Sean R.

    2012-01-01

    The work contained within this thesis is concerned with the explanation and usage of a set of theoretical procedures for the study of static and dynamic two–centre problems in the relativistic framework of Dirac’s equation. Two distinctly different theories for handling time–dependent atomic interactions are reviewed, namely semi–classical perturbation theory and a non–perturbative numerical technique based on the coupled channel equation to directly solve the time–dependent, two–centre Dirac...

  11. Social innovation for People-Centred Development

    DEFF Research Database (Denmark)

    Hulgård, Lars; P.K., Shajahan

    2013-01-01

    Social innovation is closely related to the people-centred development (PCD) framework of knowledge production. The discussion of PCD in this chapter particularly expands on the feature of empowerment and socio-political mobilization of people in social innovation......Social innovation is closely related to the people-centred development (PCD) framework of knowledge production. The discussion of PCD in this chapter particularly expands on the feature of empowerment and socio-political mobilization of people in social innovation...

  12. Vertical Integration, innovation and foreclosure

    OpenAIRE

    Allain, Marie-Laure; Chambolle, Claire; Rey, Patrick; Ecole Polytechnique Chaire d'économie

    2010-01-01

    This paper studies the potential effects of vertical integration on downstream firms’incentives to innovate. Interacting efficiently with a supplier may require information exchanges, which raises the concern that sensitive information may be disclosed to rivals. This may be particularly harmful in case of innovative activities, as it increases the risk of imitation. We show that vertical integration exacerbates this threat of imitation, which de facto degrades the integrated supplier’s abili...

  13. The Imperial College Thermophysical Properties Data Centre

    Science.gov (United States)

    Angus, S.; Cole, W. A.; Craven, R.; de Reuck, K. M.; Trengove, R. D.; Wakeham, W. A.

    1986-07-01

    The IUPAC Thermodynamic Tables Project Centre in London has at its disposal considerable expertise on the production and utilization of high-accuracy equations of state which represent the thermodynamic properties of substances. For some years they have been content to propagate this information by the traditional method of book production, but the increasing use of the computer in industry for process design has shown that an additional method was needed. The setting up of the IUPAC Transport Properties Project Centre, also at Imperial College, whose products would also be in demand by industry, afforded the occasion for a new look at the problem. The solution has been to set up the Imperial College Thermophysical Properties Data Centre, which embraces the two IUPAC Project Centres, and for it to establish a link with the existing Physical Properties Data Service of the Institution of Chemical Engineers, thus providing for the dissemination of the available information without involving the Centres in problems such as those of marketing and advertising. This paper outlines the activities of the Centres and discusses the problems in bringing their products to the attention of industry in suitable form.

  14. Perspectives on recycling centres and future developments.

    Science.gov (United States)

    Engkvist, I-L; Eklund, J; Krook, J; Björkman, M; Sundin, E

    2016-11-01

    The overall aim of this paper is to draw combined, all-embracing conclusions based on a long-term multidisciplinary research programme on recycling centres in Sweden, focussing on working conditions, environment and system performance. A second aim is to give recommendations for their development of new and existing recycling centres and to discuss implications for the future design and organisation. Several opportunities for improvement of recycling centres were identified, such as design, layout, ease with which users could sort their waste, the work environment, conflicting needs and goals within the industry, and industrialisation. Combining all results from the research, which consisted of different disciplinary aspects, made it possible to analyse and elucidate their interrelations. Waste sorting quality was recognized as the most prominent improvement field in the recycling centre system. The research identified the importance of involving stakeholders with different perspectives when planning a recycling centre in order to get functionality and high performance. Practical proposals of how to plan and build recycling centres are given in a detailed checklist. PMID:26826952

  15. Medication errors: pharmacovigilance centres in detection and prevention

    OpenAIRE

    Bencheikh, Rachida Soulaymani; Benabdallah, Ghita

    2009-01-01

    Detecting medication errors needs collaboration between various organizations, such as patient safety institutions, pharmacovigilance centres, and poison control centres. In order to evaluate the input of pharmacovigilance centres and poison control centres in detecting and evaluating medication errors a pilot project was initiated by the World Alliance for Patient Safety in collaboration with the Uppsala Monitoring Centre; the Moroccan pharmacovigilance centre acted as project coordinator. A...

  16. Engineering design of vertical test stand cryostat

    International Nuclear Information System (INIS)

    Under Indian Institutions and Fermilab collaboration, Raja Ramanna Centre for Advanced Technology and Fermi National Accelerator Laboratory are jointly developing 2K Vertical Test Stand (VTS) cryostats for testing SCRF cavities at 2K. The VTS cryostat has been designed for a large testing aperture of 86.36 cm for testing of 325 MHz Spoke resonators, 650 MHz and 1.3 GHz multi-cell SCRF cavities for Fermilab's Project-X. Units will be installed at Fermilab and RRCAT and used to test cavities for Project-X. A VTS cryostat comprises of liquid helium (LHe) vessel with internal magnetic shield, top insert plate equipped with cavity support stand and radiation shield, liquid nitrogen (LN2) shield and vacuum vessel with external magnetic shield. The engineering design and analysis of VTS cryostat has been carried out using ASME B and PV Code and Finite Element Analysis. Design of internal and external magnetic shields was performed to limit the magnetic field inside LHe vessel at the cavity surface 2 shield has been performed to check the effectiveness of LN2 cooling and for compliance with ASME piping code allowable stresses.

  17. Merchant Transmission Investment

    OpenAIRE

    Joskow, Paul L.; Tirole, Jean

    2003-01-01

    We examine the performance attributes of a merchant transmission investment framework that relies on ?market driven? transmission investment to provide the infrastructure to support competitive wholesale markets for electricity. Under a stringent set of assumptions, the merchant investment model appears to solve the natural monopoly problem and the associated need for regulating transmission companies traditionally associated with electric transmission networks. We expand the model to inc...

  18. Effects of the Centre-of-Mass Motion on the Population Trapping of Ultracold Atoms

    Institute of Scientific and Technical Information of China (English)

    熊锦; 张智明

    2003-01-01

    We investigate the effects of the atomic centre-of-mass motion on atomic population trapping in a two-mode micromaser injected with ultracold A-type three-level atoms.We find that in the mazer regime(the case in which the atomic kinetic energy is much smaller than the atom-field interaction energy),the interplay between reflection and transmission of the ultracold atom leads to the destruction of the atomic population trapping.

  19. The automotive transmission book

    CERN Document Server

    Fischer, Robert; Jürgens, Gunter; Najork, Rolf; Pollak, Burkhard

    2015-01-01

    This book presents essential information on systems and interactions in automotive transmission technology and outlines the methodologies used to analyze and develop transmission concepts and designs. Functions of and interactions between components and subassemblies of transmissions are introduced, providing a basis for designing transmission systems and for determining their potentials and properties in vehicle-specific applications: passenger cars, trucks, buses, tractors, and motorcycles. With these fundamentals the presentation provides universal resources for both state-of-the-art and future transmission technologies, including systems for electric and hybrid electric vehicles.

  20. To the problem of topological optimization of data processing and transmission networks in development of the automatic control system ''Atom''

    International Nuclear Information System (INIS)

    Some optimization problems occurring in developing the automatic control system (ASC) of a commercial amalgamation (ACS-ATOM), assessments of economically optimal structure of location of computation centres and means of data transmission in particular are considered

  1. Visits to Tier-1 Computing Centres

    CERN Multimedia

    Dario Barberis

    At the beginning of 2007 it became clear that an enhanced level of communication is needed between the ATLAS computing organisation and the Tier-1 centres. Most usual meetings are ATLAS-centric and cannot address the issues of each Tier-1; therefore we decided to organise a series of visits to the Tier-1 centres and focus on site issues. For us, ATLAS computing management, it is most useful to realize how each Tier-1 centre is organised, and its relation to the associated Tier-2s; indeed their presence at these visits is also very useful. We hope it is also useful for sites... at least, we are told so! The usual participation includes, from the ATLAS side: computing management, operations, data placement, resources, accounting and database deployment coordinators; and from the Tier-1 side: computer centre management, system managers, Grid infrastructure people, network, storage and database experts, local ATLAS liaison people and representatives of the associated Tier-2s. Visiting Tier-1 centres (1-4). ...

  2. UV LED lighting for automated crystal centring

    International Nuclear Information System (INIS)

    A low-cost light-emitting diode (LED) UV source has been developed for facilitating macromolecular sample centring in the X-ray beam. A direct outcome of the exponential growth of macromolecular crystallography is the continuously increasing demand for synchrotron beam time, both from academic and industrial users. As more and more projects entail screening a profusion of sample crystals, fully automated procedures at every level of the experiments are being implemented at all synchrotron facilities. One of the major obstacles to achieving such automation lies in the sample recognition and centring in the X-ray beam. The capacity of UV light to specifically react with aromatic residues present in proteins or with DNA base pairs is at the basis of UV-assisted crystal centring. Although very efficient, a well known side effect of illuminating biological samples with strong UV sources is the damage induced on the irradiated samples. In the present study the effectiveness of a softer UV light for crystal centring by taking advantage of low-power light-emitting diode (LED) sources has been investigated. The use of UV LEDs represents a low-cost solution for crystal centring with high specificity

  3. Scavenger hunt in the CERN Computing Centre

    CERN Multimedia

    CERN Bulletin

    2013-01-01

    Hidden among the racks of servers and disks in the CERN Computing Centre, you’ll find Hawaiian dancers, space aliens, gorillas… all LEGO® figurines! These characters were placed about the Centre for the arrival of Google’s Street View team for the world to discover.   PLEASE NOTE THAT THE COMPETITION IS OVER. ONLY FOR REFERENCE, HERE IS THE ORIGINAL ARTICLE. We’re pleased to announce our first global scavenger hunt! Spot three LEGO® figurines using Google’s Street View and you’ll be entered to win a gift of your choice from our CERN Gift Guide. A LEGO® figurine in the CERN Computing Centre, as seen on Google Street View. Here are the details: Find at least three LEGO® figurines hidden around the CERN Computing Centre using Google Street View.   Take screencaps of the figurines and e-mail the pictures to TreasureHunt-ComputingCentre@cern.ch. This email is no longer active.   The...

  4. The Aube centre. 1997 statement; Le centre de l`Aube. Bilan 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-09-01

    Since January 1992 the Aube centre ensures the storage of 90% of the short life radioactive wastes produced in France. This educational booklet describes the organization of the activities in the centre from the storage of wastes to the radioactivity surveillance of the environment (air, surface and ground waters, river sediments, plants and milk). (J.S.)

  5. A day in the CERN Control Centre

    CERN Multimedia

    Rosaria Marraffino

    2015-01-01

    The CERN Control Centre (CCC) is the nerve centre of the CERN beam systems. From this room, the experts prepare, monitor, adjust, and control the particle beams that circulate throughout the accelerator complex while ensuring that the services and the technical infrastructure work flawlessly. Buttons, screens, telephones, lights (but no sound): in the CCC, everything is ready to make it possible for the LHC to reach the unprecedented energies expected at Run 2.   Seen from above, the CERN Control Centre resembles the shape of a quadrupole magnet. The consoles are distributed in four circles, called “islands”, dedicated to the LHC, the SPS, the PS Complex and the Technical Infrastructure (TI) respectively. Spread between TI and LHC are the Cryogenics consoles. Being in the same room allows the 24h-manned islands to be constantly in touch with one another, thus ensuring the best performance of the machines. At the LHC island, operators are currently busy training the magnet...

  6. Medical applications in a nuclear research centre

    International Nuclear Information System (INIS)

    In these days of public aversion to nuclear power, it can be important to point at the medical applications of ionising radiation. Not only the general public, but also the authorities and research centres have to be aware of these medical applications, which are not without risk for public health. Now that funding for nuclear research is declining, an opening to the medical world can give new opportunities to a nuclear research centre. A lot of research could be done where the tools developed for the nuclear power world are very useful. Even new applications for the research reactors like BNCT (boron neutron capture therapy) can be envisaged for the near future. In this contribution an overview will be given of the different techniques used in the medical world with ionising radiation. The specific example of the Belgian Nuclear Research Centre will be given where the mission statement was changed to include a certain number of medical research topics. (authors)

  7. Occupational deprivation in an asylum centre:

    DEFF Research Database (Denmark)

    Morville, Anne-Le; Erlandsson, Lena-Karin

    2013-01-01

    This article presents a study of three asylum-seeking men from Iran and Afghanistan. It aimed to explore how and if they experienced occupations as occupations in a Danish asylum centre and how their life experience shaped their choice and value of current occupations. In-depth narrative interviews...... explored the participants’ occupational history and its influence on their occupations in the asylum centre. A thematic analysis showed that the participants had been subjected to occupational disruption and deprivation by politically oppressive systems even before their flight. Their occupations in...... Denmark were to a certain extent influenced by their earlier occupations and the current occupational deprivation they all experienced was due to limited possibilities in the centre. Although they tried their best to fill their days and create structure, there was a loss of valued occupations and a...

  8. Optimizing Data Centre Energy and Environmental Costs

    Science.gov (United States)

    Aikema, David Hendrik

    Data centres use an estimated 2% of US electrical power which accounts for much of their total cost of ownership. This consumption continues to grow, further straining power grids attempting to integrate more renewable energy. This dissertation focuses on assessing and reducing data centre environmental and financial costs. Emissions of projects undertaken to lower the data centre environmental footprints can be assessed and the emission reduction projects compared using an ISO-14064-2-compliant greenhouse gas reduction protocol outlined herein. I was closely involved with the development of the protocol. Full lifecycle analysis and verifying that projects exceed business-as-usual expectations are addressed, and a test project is described. Consuming power when it is low cost or when renewable energy is available can be used to reduce the financial and environmental costs of computing. Adaptation based on the power price showed 10--50% potential savings in typical cases, and local renewable energy use could be increased by 10--80%. Allowing a fraction of high-priority tasks to proceed unimpeded still allows significant savings. Power grid operators use mechanisms called ancillary services to address variation and system failures, paying organizations to alter power consumption on request. By bidding to offer these services, data centres may be able to lower their energy costs while reducing their environmental impact. If providing contingency reserves which require only infrequent action, savings of up to 12% were seen in simulations. Greater power cost savings are possible for those ceding more control to the power grid operator. Coordinating multiple data centres adds overhead, and altering at which data centre requests are processed based on changes in the financial or environmental costs of power is likely to increase this overhead. Tests of virtual machine migrations showed that in some cases there was no visible increase in power use while in others power use

  9. Imperial College Reactor Centre annual report. 1984

    International Nuclear Information System (INIS)

    The following new equipment is noted; for atomic absorption spectrometry to supplement the neutron activation analysis, and an additional nuclear data analysis system to improve the quality and speed of the service to users of the Centre's facilities. Users include undergraduates from the University of London, outside bodies such as the British Musueum, as well as departments of Colleges of the University of London. The reactor lost only three days through failures or faults. Two replacement fuel elements were put into the reactor during the year. The report contains brief accounts of 34 research programmes at the Centre. (U.K.)

  10. User-Centred BCI Videogame Design

    OpenAIRE

    Loup-Escande, Emilie; Lotte, Fabien; LOUP, Guillaume; Lécuyer, Anatole

    2015-01-01

    This chapter aims to offer a user-centred methodological framework to guide the design and evaluation of Brain-Computer Interface videogames. This framework is based on the contributions of ergonomics to ensure these games are well suited for their users (i.e., players). It provides methods, criteria and metrics to complete the different phases required by ae human-centred design process. This aims to understand the context of use, specify the user needs and evaluate the solutions in order to...

  11. Alligning vertical collection relevance with user intent

    NARCIS (Netherlands)

    Zhou, Ke; Demeester, Thomas; Nguyen, Dong; Hiemstra, Djoerd; Trieschnigg, Dolf

    2014-01-01

    Selecting and aggregating different types of content from multiple vertical search engines is becoming popular in web search. The user vertical intent, the verticals the user expects to be relevant for a particular information need, might not correspond to the vertical collection relevance, the vert

  12. Multiservice Vertical Handoff Decision Algorithms

    Directory of Open Access Journals (Sweden)

    Zhu Fang

    2006-01-01

    Full Text Available Future wireless networks must be able to coordinate services within a diverse-network environment. One of the challenging problems for coordination is vertical handoff, which is the decision for a mobile node to handoff between different types of networks. While traditional handoff is based on received signal strength comparisons, vertical handoff must evaluate additional factors, such as monetary cost, offered services, network conditions, and user preferences. In this paper, several optimizations are proposed for the execution of vertical handoff decision algorithms, with the goal of maximizing the quality of service experienced by each user. First, the concept of policy-based handoffs is discussed. Then, a multiservice vertical handoff decision algorithm (MUSE-VDA and cost function are introduced to judge target networks based on a variety of user- and network-valued metrics. Finally, a performance analysis demonstrates that significant gains in the ability to satisfy user requests for multiple simultaneous services and a more efficient use of resources can be achieved from the MUSE-VDA optimizations.

  13. Hybrid Vertical-Cavity Laser

    DEFF Research Database (Denmark)

    2010-01-01

    The present invention provides a light source (2) for light circuits on a silicon platform (3). A vertical laser cavity is formed by a gain region (101) arranged between a top mirror (4) and a bottom grating-mirror (12) in a grating region (11) in a silicon layer (10) on a substrate. A waveguide...

  14. Trade Liberalisation and Vertical Integration

    DEFF Research Database (Denmark)

    Bache, Peter Arendorf; Laugesen, Anders

    We build a three-country model of international trade in final goods and intermediate inputs and study the relation between different types of trade liberalisation and vertical integration. Firms are heterogeneous with respect to both productivity and factor intensity as observed in data. Final...

  15. Hydrostatic transmission design

    OpenAIRE

    Dalda Rivas, Ignacio

    2009-01-01

    This project treats the analysis of the hydrostatic transmission dynamic properties using a simulation model, which has been done with the simulation program AMESim. That simulation has been the main work in the project, especially because it is a good way to understand how a hydrostatic transmission works. The hydrostatic transmission are used in heavy vehicles such as earth moving machines, agriculture machines, forest machines, industrial and mining lifters. Nowadays, the demand of that...

  16. Series Transmission Line Transformer

    Science.gov (United States)

    Buckles, Robert A.; Booth, Rex; Yen, Boris T.

    2004-06-29

    A series transmission line transformer is set forth which includes two or more of impedance matched sets of at least two transmissions lines such as shielded cables, connected in parallel at one end ans series at the other in a cascading fashion. The cables are wound about a magnetic core. The series transmission line transformer (STLT) which can provide for higher impedance ratios and bandwidths, which is scalable, and which is of simpler design and construction.

  17. The monetary transmission mechanism

    OpenAIRE

    Ireland, Peter N.

    2006-01-01

    The monetary transmission mechanism describes how policy-induced changes in the nominal money stock or the short-term nominal interest rate impact on real variables such as aggregate output and employment. Specific channels of monetary transmission operate through the effects that monetary policy has on interest rates, exchange rates, equity and real estate prices, bank lending, and firm balance sheets. Recent research on the transmission mechanism seeks to understand how these channels work ...

  18. Tracking transmission of the zoonosis Toxoplasma gondii.

    Science.gov (United States)

    Smith, Judith E

    2009-01-01

    Toxoplasma gondii is a highly successful parasite that infects many host species and has colonised a wide range of habitats. Review of the parasite's life cycle demonstrates that it has become adapted to exploit multiple routes of transmission through a sexual cycle in the definitive host and asexually, through carnivory, and by vertical transmission. These alternative routes may operate synergistically to enhance transmission, but they might also provide a vehicle for selection leading to partitioning of strains in the environment. Genetic analysis has shown that parasite population structure varies globally. In South America, there is high strain diversity while in North America, Europe and Africa three clonal strain types predominate. This may imply a shift from sexual to asexual transmission. Mapping of the parasite genome has provided a wealth of markers for strain characterisation. Close genotyping of isolates gives evidence of multiple infection and recombination in natural populations and reveals differences in both the distribution and the phenotype of strains. More intensive epidemiological studies are now required to unravel the networks of transmission operating within defined habitats. PMID:19289193

  19. Vertical jumping performance of bonobo (Pan paniscus) suggests superior muscle properties

    OpenAIRE

    Scholz, Melanie N; D'Août, Kristiaan; Bobbert, Maarten F.; Aerts, Peter

    2006-01-01

    Vertical jumping was used to assess muscle mechanical output in bonobos and comparisons were drawn to human jumping. Jump height, defined as the vertical displacement of the body centre of mass during the airborne phase, was determined for three bonobos of varying age and sex. All bonobos reached jump heights above 0.7 m, which greatly exceeds typical human maximal performance (0.3–0.4 m). Jumps by one male bonobo (34 kg) and one human male (61.5 kg) were analysed using an inverse dynamics ap...

  20. The extrasolar planet atmosphere and exosphere: Emission and transmission spectroscopy

    CERN Document Server

    Tinetti, Giovanna

    2008-01-01

    We have entered the phase of extrasolar planets characterization, probing their atmospheres for molecules, constraining their horizontal and vertical temperature profiles and estimating the contribution of clouds and hazes. We report here a short review of the current situation using ground based and space based observations, and present the transmission spectra of HD189733b in the spectral range 0.5-24 microns.

  1. Microfluidic chip for high resolution transmission electron microscopy

    DEFF Research Database (Denmark)

    2013-01-01

    A Microfluidic chip (100) for transmission electron microscopy has a monolithic body (101) with a front side (102) and a back side (103). The monolithic body (101) comprises an opening (104) on the back side (103) extending in a vertical direction from the back side (103) to a membrane (107...

  2. The Australian Centre for Minesite Rehabilitation Research

    International Nuclear Information System (INIS)

    The Australian Centre for Minesite Rehabilitation Research (ACMRR) is a joint venture between the Australian mining industry through the Australian Mineral Industries Research Association Ltd. (AMIRA) and three of the organizations working most actively in this area in Australia: CSIRO Minesite Rehabilitation Research Program; University of Queensland Centre for Mined Land Rehabilitation; and Curtin University Mulga Research Centre. The ACMRR was established in July 1993 to provide a national framework to conduct Strategic Research into minesite rehabilitation. It is an industry led and funded initiative. The Goals of the Centre include: to conduct strategic research into minesite rehabilitation to provide sustainable environmental solutions which are acceptable to industry, government and the community; to be recognized as a center of excellence undertaking commissioned research on minesite rehabilitation in an independent and thorough manner; to provide scientific and technological foundations to facilitate industry and government in setting acceptable standards; to act as networking and communications focus; and to enhance education and training in minesite rehabilitation. Strategic Research Programs in: Water Systems--downstream surface and groundwater quality; Land--the long-term behavior and stability of constructed landforms; Ecosystems--the long-term sustainability of constructed landforms; Waste--the long-term treatment and disposal of waste products; will allow the ACMRR to achieve these goals through specific research projects in these areas, developed with industry sponsors. This paper will discuss their progress to date, research projects underway, and plans for the future

  3. Learner-Centred Education and "Cultural Translation"

    Science.gov (United States)

    Thompson, Paul

    2013-01-01

    This paper contests the proposal that learner-centred education (LCE) may simply be a western construct, irrelevant to the current educational needs of developing countries, by arguing that its specific forms will be more effective when introduced through small-scale institutional relationships than through large-scale contracts with national…

  4. The young centre of the Earth

    DEFF Research Database (Denmark)

    Uggerhøj, Ulrik Ingerslev; Mikkelsen, Rune E.; Faye, Jan

    2016-01-01

    We treat, as an illustrative example of gravitational time dilation in relativity, the observation that the centre of the Earth is younger than the surface by an appreciable amount. Richard Feynman first made this insightful point and presented an estimate of the size of the effect in a talk; a...

  5. Student-Centred Learning: A Humanist Perspective

    Science.gov (United States)

    Tangney, Sue

    2014-01-01

    The notion of student-centred learning is often not defined; within the pedagogic literature it is generally associated with constructivism or principles associated with a constructivist environment such as building on prior knowledge, purposeful active learning and sense-making. An informal enquiry into conceptions of university staff prior to…

  6. The BNFL technology centre at Sellafield

    International Nuclear Information System (INIS)

    A description is given of the BNFL technology centre at Sellafield. Special emphasis is on the facility plan and construction, the high active hot-cells, the laboratories, the high energy interrogation facility, and the rigg hall. Further, the servicing well as the contract strategy are discussed

  7. The fragility of human-centred design

    NARCIS (Netherlands)

    Steen, M.G.D.

    2008-01-01

    In human-centred design (HCD), researchers and designers develop products in cooperation with the potential users of these products. They attempt to give users a voice or a role in their projects, with the intention of developing products that match users' needs and preferences. This approach is esp

  8. Centring the Subject in Order to Educate

    Science.gov (United States)

    Webster, R. Scott

    2007-01-01

    It is important for educators to recognise that the various calls to decentre the subject--or self--should not be interpreted as necessarily requiring the removal of the subject altogether. Through the individualism of the Enlightenment the self was centred. This highly individualistic notion of the sovereign self has now been decentred especially…

  9. Renovation of the CERN Computer Centre

    CERN Multimedia

    Patrice Loïez

    2003-01-01

    The Computer Centre at CERN is seen after half of the equipment is the large ground floor room has been removed. A large-scale spring-cleaning operation took place before renovation work for the new CERN Grid system began. Fifteen kilometres of cables that were no longer needed were removed from the cavity floor for recycling.

  10. Enhancing person-centred communication in NICU

    DEFF Research Database (Denmark)

    Weis, Janne; Zoffmann, Vibeke; Egerod, Ingrid

    2015-01-01

    Aims of this article were (a) to explore how parents of premature infants experience guided family-centred care (GFCC), and (b) to compare how parents receiving GFCC versus standard care (SC) describe nurse-parent communication in the neonatal intensive care unit....

  11. Cactus: The Centres of a Triangle

    Science.gov (United States)

    Hyde, Hartley

    2009-01-01

    This is the first of two articles which describe how to use "JavaSketchPad" to explore the centres of a triangle. This introductory exercise is suggested in the GSP "Workshop Guide". Students can use "JavaSketchPad Interactive Geometry" (JSP) at home at no cost. They are likely to impress their parents with their enthusiasm for geometry and all…

  12. Interorganisatorisk styring i Shared Service Centre

    DEFF Research Database (Denmark)

    Harritz, Daniel

    2011-01-01

    I den offentlige sektor er der en stigende udbredelse af Shared Service Centre (SSC). Men der er endnu meget lidt viden om de interorganisatoriske styringsproblemstillinger, der opstår når et SSC oprettes. I denne artikel præsenteres, ud fra et interorganisatorisk perspektiv, en styringsramme der...

  13. In the Field: The Canadian Ecology Centre.

    Science.gov (United States)

    Magee, Clare

    2000-01-01

    The Canadian Ecology Centre (Ontario) offers year-round residential and day programs in outdoor and environmental education for secondary students, field placement and internship opportunities for college students, and ecotourism programs, while providing employment and tax revenues to the local community. Dubbed consensus environmentalism, the…

  14. Vertical Disintegration in the European Electricity Sector: Empirical Evidence on Lost Synergies

    OpenAIRE

    Klaus Gugler; Mario Liebensteiner; Stephan Schmitt

    2014-01-01

    The EU has been promoting unbundling of the transmission grid from other stages of the electricity supply chain with the aim of fostering competition in the upstream stage of electricity generation. At presence, ownership unbundling is the predominant form of unbundling in Europe. However, the benefits of increased competition from ownership unbundling of the transmission grid may come at the cost of lost vertical synergies between the formerly integrated stages of electricity supply. The pol...

  15. Nuclear Electric Visitor Centres - Innovation and inspiration

    International Nuclear Information System (INIS)

    Full text: This eight minute video demonstrates the approach taken by Nuclear Electric to exhibitions that are open to the public. The information is given both visually - with excerpts from some of the attractions on display at the centres - and in comments from interviews with visitors, the centre guides and the man responsible for many of the exhibits featured in the video. on one side are the schoolchildren who are visiting the exhibition and are seen both playing and learning as they press buttons, watch videos, 'meet' Michael Faraday, and learn about radiation - its disposal and its safe transportation. The headmaster of the school is interviewed and explains that the exhibition is helping his children understand the importance of electricity to their world. on the other side is Jackie Lucas, the visitor centre manager, explaining what the public make of the exhibition. We see her staff greeting the children and helping them to understand the show. The designer of the exhibition, Len Upton explains how you go about making an exhibition such as this both informative and fun. Also interviewed is the man behind many of the exhibitions featured at Nuclear Electric's visitor centres up and down the country, Nicholas Mullane. He explains the purpose of the exhibition and what messages it imparts. The video is presented in split-screen or composite format, whereby the interviewee and children are often presented together. Excerpts from the various videos on display are presented as both how they are seen from the floor, as well as the full screen effect of the various programmes. The video gives much of the feeling of fun to be gained at the exhibition, as well as showing the educational benefits to be gained from a couple of hours at one of Nuclear Electric's visitor centres. Copies of the video can be obtained from Bob Fenton at Nuclear Electric. (Fax: ++44 1 452 652 443). (author)

  16. Person-centred care in nursing documentation.

    LENUS (Irish Health Repository)

    Broderick, Margaret C

    2012-12-07

    BACKGROUND: Documentation is an essential part of nursing. It provides evidence that care has been carried out and contains important information to enhance the quality and continuity of care. Person-centred care (PCC) is an approach to care that is underpinned by mutual respect and the development of a therapeutic relationship between the patient and nurse. It is a core principle in standards for residential care settings for older people and is beneficial for both patients and staff (International Practice Development in Nursing and Healthcare, Chichester, Blackwell, 2008 and The Implementation of a Model of Person-Centred Practice in Older Person Settings, Dublin, Health Service Executive, 2010a). However, the literature suggests a lack of person-centredness within nursing documentation (International Journal of Older People Nursing 2, 2007, 263 and The Implementation of a Model of Person-Centred Practice in Older Person Settings, Dublin, Health Service Executive, 2010a). AIMS AND OBJECTIVES: To explore nursing documentation in long-term care, to determine whether it reflected a person-centred approach to care and to describe aspects of PCC as they appeared in nursing records. METHOD: A qualitative descriptive study using the PCN framework (Person-centred Nursing; Theory and Practice, Oxford, Wiley-Blackwell, 2010) as the context through which nursing assessments and care plans were explored. RESULTS: Findings indicated that many nursing records were incomplete, and information regarding psychosocial aspects of care was infrequent. There was evidence that nurses engaged with residents and worked with their beliefs and values. However, nursing documentation was not completed in consultation with the patient, and there was little to suggest that patients were involved in decisions relating to their care. IMPLICATIONS FOR PRACTICE: The structure of nursing documentation can be a major obstacle to the recording of PCC and appropriate care planning. Documentation

  17. Regional Supervision Centres for Environmental Protection in China: Functions and Limitations

    Directory of Open Access Journals (Sweden)

    Qingzhi Huan

    2011-01-01

    Full Text Available China’s Ministry of Environmental Protection (MEP, has set up six regional Supervision Centres for Environmental Protection (SCEPs in recent years. The creation of the SCEPs reflects the “green will” of Chinese government, to reverse the ever-worsening environmental situation throughout China by strengthening vertical supervision of the environmental laws and policies enforcement. A primary analysis focusing on the South China Supervision Centre (SCSC has clearly shown, however, that the SCEPs today can only perform well in the concrete or “small” tasks – most of them designated or handed over by the MEP – rather than in the complicated or “big” issues. To make the SCEPs do more and better, the most desirable but radical policy choice is to reshape them into fully authorised regional “sub-bureaus” of the MEP.

  18. Kinetic characterization of the photosynthetic reaction centres in microalgae by means of fluorescence methodology.

    Science.gov (United States)

    Gargano, Immacolata; Olivieri, Giuseppe; Spasiano, Danilo; Andreozzi, Roberto; Pollio, Antonino; Marotta, Raffaele; D'Ambrosio, Nicola; Marzocchella, Antonio

    2015-10-20

    The kinetic characterization of the photosynthetic activity in autotrophic microalgae plays a key role in the design of optimized photobioreactors. This paper presents a procedure to assess kinetic parameters of a three-state photosynthetic reaction centres model. Four kinetic parameters of the model were assessed by processing the time-series measurements of pulse-amplitude modulation fluorimetry. The kinetic parameters were assessed for several microalgal strains (Stichococcus bacillaris, Scenedesmus vacuolatus, Chlamydomonas reinhardtii, Chlorella vulgaris) growth in vertical and inclined bubble columns and irradiated by white-light or red/blue light. The procedure was successfully applied to the investigated strains. The assessed parameters allow identifying the irradiance range under which: the photochemical process is controlled by the photons capture; the photoinhibition competes with the photochemical quenching. The analysis of the time-scale of the photosynthetic reaction centres as a function of the irradiance allows interpreting the performances of photobioreactors characterized by non-homogeneous irradiance. PMID:26216180

  19. Topics on Electricity Transmission Pricing

    International Nuclear Information System (INIS)

    -subsidization, the largest state-owned firm was split to form Statkraft SF, Norway's largest generation company, and Statnett SF, the major transmission company. Statnett is also the system operator of the entire Norwegian power system. Many distribution companies, usually publicly owned, are still part of vertically integrated companies, but there is strict separation of the financial accounts for transmission/distribution and generation/marketing. Trading is accomplished through several channels. The largest organized market is the common Norwegian-Swedish pool, NordPool. NordPool ASA is owned by Statnett Marked (which is a subsidiary of Statnett) and the Swedish grid-company, Svenska Kraftnaet. NordPool also supports the Finnish and Danish markets, thus through cooperation with the grid-companies of Denmark (Eltra) and Finland (Fingrid), locational markets are provided in these countries as well. Unlike England and Wales, only part of actual production is traded on this market. In addition, independent brokers offer various energy-contracts and facilitate bilateral contracts. In 1998 22% of the energy was traded on the hourly day-ahead (spot) market of NordPool. NordPool also organizes a forward and futures market and settles contracts from the regulation market organized by Statnett. The regulation market is a realtime market used to settle imbalances in real time. In total, close to 30% of the energy traded is organized through NordPool, and this share is increasing year by year. The efficiency of the market is heavily affected by the operation and pricing of the transmission system, and the topic of this thesis concerns the interaction of the transmission network and the energy markets. Throughout, the findings are illustrated by means of simple examples. This is to enhance readability and intuition. To start with, chapter 2 is devoted to power flow models, whereas chapter 3 provides an overview of models developed to efficiently coordinate the allocation of transmission

  20. A Unified Global Reference Frame of Vertical Crustal Movements by Satellite Laser Ranging

    Directory of Open Access Journals (Sweden)

    Xinhui Zhu

    2016-02-01

    Full Text Available Crustal movement is one of the main factors influencing the change of the Earth system, especially in its vertical direction, which affects people’s daily life through the frequent occurrence of earthquakes, geological disasters, and so on. In order to get a better study and application of the vertical crustal movement,as well as its changes, the foundation and prerequisite areto devise and establish its reference frame; especially, a unified global reference frame is required. Since SLR (satellite laser ranging is one of the most accurate space techniques for monitoring geocentric motion and can directly measure the ground station’s geocentric coordinates and velocities relative to the centre of the Earth’s mass, we proposed to take the vertical velocity of the SLR technique in the ITRF2008 framework as the reference frame of vertical crustal motion, which we defined as the SLR vertical reference frame (SVRF. The systematic bias between other velocity fields and the SVRF was resolved by using the GPS (Global Positioning System and VLBI (very long baseline interferometry velocity observations, and the unity of other velocity fields and SVRF was realized,as well. The results show that it is feasible and suitable to take the SVRF as a reference frame, which has both geophysical meanings and geodetic observations, so we recommend taking the SLR vertical velocity under ITRF2008 as the global reference frame of vertical crustal movement.

  1. A Unified Global Reference Frame of Vertical Crustal Movements by Satellite Laser Ranging.

    Science.gov (United States)

    Zhu, Xinhui; Wang, Ren; Sun, Fuping; Wang, Jinling

    2016-01-01

    Crustal movement is one of the main factors influencing the change of the Earth system, especially in its vertical direction, which affects people's daily life through the frequent occurrence of earthquakes, geological disasters, and so on. In order to get a better study and application of the vertical crustal movement,as well as its changes, the foundation and prerequisite areto devise and establish its reference frame; especially, a unified global reference frame is required. Since SLR (satellite laser ranging) is one of the most accurate space techniques for monitoring geocentric motion and can directly measure the ground station's geocentric coordinates and velocities relative to the centre of the Earth's mass, we proposed to take the vertical velocity of the SLR technique in the ITRF2008 framework as the reference frame of vertical crustal motion, which we defined as the SLR vertical reference frame (SVRF). The systematic bias between other velocity fields and the SVRF was resolved by using the GPS (Global Positioning System) and VLBI (very long baseline interferometry) velocity observations, and the unity of other velocity fields and SVRF was realized,as well. The results show that it is feasible and suitable to take the SVRF as a reference frame, which has both geophysical meanings and geodetic observations, so we recommend taking the SLR vertical velocity under ITRF2008 as the global reference frame of vertical crustal movement. PMID:26867197

  2. A Unified Global Reference Frame of Vertical Crustal Movements by Satellite Laser Ranging

    Science.gov (United States)

    Zhu, Xinhui; Wang, Ren; Sun, Fuping; Wang, Jinling

    2016-01-01

    Crustal movement is one of the main factors influencing the change of the Earth system, especially in its vertical direction, which affects people’s daily life through the frequent occurrence of earthquakes, geological disasters, and so on. In order to get a better study and application of the vertical crustal movement, as well as its changes, the foundation and prerequisite areto devise and establish its reference frame; especially, a unified global reference frame is required. Since SLR (satellite laser ranging) is one of the most accurate space techniques for monitoring geocentric motion and can directly measure the ground station’s geocentric coordinates and velocities relative to the centre of the Earth’s mass, we proposed to take the vertical velocity of the SLR technique in the ITRF2008 framework as the reference frame of vertical crustal motion, which we defined as the SLR vertical reference frame (SVRF). The systematic bias between other velocity fields and the SVRF was resolved by using the GPS (Global Positioning System) and VLBI (very long baseline interferometry) velocity observations, and the unity of other velocity fields and SVRF was realized, as well. The results show that it is feasible and suitable to take the SVRF as a reference frame, which has both geophysical meanings and geodetic observations, so we recommend taking the SLR vertical velocity under ITRF2008 as the global reference frame of vertical crustal movement. PMID:26867197

  3. Polymer wedge for perfectly vertical light coupling to silicon

    Science.gov (United States)

    Schrauwen, J.; Scheerlinck, S.; Van Thourhout, D.; Baets, R.

    2009-02-01

    We present the design and fabrication of a refractive polymer wedge that allows perfectly vertical coupling of light into a silicon waveguide, which is of interest for flip-chip bonding of vertical cavity emitting light sources on a silicon integrated circuit. The structure includes a conventional diffractive grating coupler that requires off-normal incidence to avoid second order Bragg reflections. The polymer wedge is thus used to refract vertically impinging light into an off-normal wave that couples into the underlying grating. The fabrication involves two steps: mold fabrication and imprint replication. Firstly negative wedge-shaped craters are etched into a quartz mold by Focused-ion-beam milling. Secondly the mold is used to imprint a UV-curable polymer onto a silicon chip containing waveguides and grating couplers, and so replicating the wedges. The characterization setup consisted of a fiber-to-fiber transmission measurement of a silicon waveguide equipped with a pair of grating couplers and polymer wedges. The obtained fiber coupling efficiency was equal to the efficiency of regular grating couplers and fiber positioned at an off-normal angle. The proposed fabrication method enables low cost integration of vertical cavity emitting light sources on silicon integrated photonic circuits.

  4. Poverty and price transmission

    DEFF Research Database (Denmark)

    Elleby, Christian

    A key parameter determining the welfare impact from a world market shock is the transmission elasticity which measures the average domestic response to an international price change. Many studies have estimated price transmission elasticities for a large number of countries but the variation in t...

  5. Data Transmission Concepts.

    Science.gov (United States)

    Christenson, Chris

    1995-01-01

    Introduces some basic concepts related to the transmission of data from a computer to its peripherals to help distance educators make decisions regarding computer equipment purchases for their institutions. The following data transmission concepts are described: cables, serial and parallel, synchronous and asynchronous, bandwidth, and analog and…

  6. Nonlinear magnetoinductive transmission lines

    CERN Document Server

    Lazarides, Nikos; Tsironis, G P

    2011-01-01

    Power transmission in one-dimensional nonlinear magnetic metamaterials driven at one end is investigated numerically and analytically in a wide frequency range. The nonlinear magnetic metamaterials are composed of varactor-loaded split-ring resonators which are coupled magnetically through their mutual inductances, forming thus a magnetoiductive transmission line. In the linear limit, significant power transmission along the array only appears for frequencies inside the linear magnetoinductive wave band. We present analytical, closed form solutions for the magnetoinductive waves transmitting the power in this regime, and their discrete frequency dispersion. When nonlinearity is important, more frequency bands with significant power transmission along the array may appear. In the equivalent circuit picture, the nonlinear magnetoiductive transmission line driven at one end by a relatively weak electromotive force, can be modeled by coupled resistive-inductive-capacitive (RLC) circuits with voltage-dependent cap...

  7. The Manche storage centre: Annual report 2010; Centre de stockage de la Manche Rapport annuel 2010

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    This report presents the installations of the CSM (Centre de Stockage de la Manche), the first French centre for the surface storage of low and intermediate level radioactive wastes. It briefly describes the site and its buildings, the multi-layer principle which is used to cover the wastes, how surface and drainage waters are managed, which controls are performed. It presents the different nuclear safety measures: principles, prevention measures, technical measures to meet the requirements, the legal plan for the control of the Centre and its environment, the quality management organization. It presents the measures regarding radioprotection and safety, indicates incidents and accidents which occurred in 2010, gives information and data on release management (effluents, controls, obtained data on surface and underground waters in different points). It briefly comments how the Centre's wastes are managed, evokes the case of other pollutions, and indicates actions performed in terms of public information

  8. Vertically Integrated Circuits at Fermilab

    Energy Technology Data Exchange (ETDEWEB)

    Deptuch, Grzegorz; Demarteau, Marcel; Hoff, James; Lipton, Ronald; Shenai, Alpana; Trimpl, Marcel; Yarema, Raymond; Zimmerman, Tom; /Fermilab

    2009-01-01

    The exploration of the vertically integrated circuits, also commonly known as 3D-IC technology, for applications in radiation detection started at Fermilab in 2006. This paper examines the opportunities that vertical integration offers by looking at various 3D designs that have been completed by Fermilab. The emphasis is on opportunities that are presented by through silicon vias (TSV), wafer and circuit thinning and finally fusion bonding techniques to replace conventional bump bonding. Early work by Fermilab has led to an international consortium for the development of 3D-IC circuits for High Energy Physics. The consortium has submitted over 25 different designs for the Fermilab organized MPW run organized for the first time.

  9. INTERNATIONAL SPECIALIZATION AND VERTICAL DIFFERENTIATION

    Directory of Open Access Journals (Sweden)

    Furia Donatella

    2010-07-01

    Full Text Available During the last decades, market segmentation and intra-industry trade have become increasingly relevant. The underlying hypothesis of our work is that distinct articles have heterogeneous potential for vertical differentiation, implying that different patterns of international specialization should be identifiable. We carry out an analysis on revealed comparative advantage (through the Lafay Index in specific sectors of interest. Then we highlight the emergence of diverse degrees of product quality differentiation among sectors (through the Relative Quality Index. Results confirm our hypothesis. Indeed it appears that only certain goods, for which the pace of either creative or technological innovation (or both is particularly fast, present a high degree of vertical differentiation and market segmentation. This allows countries to specialize in a particular product variety and gain market power position for that variety. These findings should be taken in due consideration when designing trade policies.

  10. Kinematic Fitting of Detached Vertices

    Energy Technology Data Exchange (ETDEWEB)

    Paul Mattione

    2007-05-01

    The eg3 experiment at the Jefferson Lab CLAS detector aims to determine the existence of the $\\Xi_{5}$ pentaquarks and investigate the excited $\\Xi$ states. Specifically, the exotic $\\Xi_{5}^{--}$ pentaquark will be sought by first reconstructing the $\\Xi^{-}$ particle through its weak decays, $\\Xi^{-}\\to\\pi^{-}\\Lambda$ and $\\Lambda\\to\\pi^{-}$. A kinematic fitting routine was developed to reconstruct the detached vertices of these decays, where confidence level cuts on the fits are used to remove background events. Prior to fitting these decays, the exclusive reaction $\\gamma D\\rightarrow pp\\pi^{-}$ was studied in order to correct the track measurements and covariance matrices of the charged particles. The $\\Lambda\\rightarrow p\\pi^{-}$ and $\\Xi^{-}\\to\\pi^{-}\\Lambda$ decays were then investigated to demonstrate that the kinematic fitting routine reconstructs the decaying particles and their detached vertices correctly.

  11. Strategic Inventories in Vertical Contracts

    OpenAIRE

    Krishnan Anand; Ravi Anupindi; Yehuda Bassok

    2008-01-01

    Classical reasons for carrying inventory include fixed (nonlinear) production or procurement costs, lead times, nonstationary or uncertain supply/demand, and capacity constraints. The last decade has seen active research in supply chain coordination focusing on the role of incentive contracts to achieve first-best levels of inventory. An extensive literature in industrial organization that studies incentives for vertical controls largely ignores the effect of inventories. Does the ability to ...

  12. Vertical axis wind turbine acoustics

    OpenAIRE

    Pearson, Charlie

    2014-01-01

    Increasing awareness of the issues of climate change and sustainable energy use has led to growing levels of interest in small-scale, decentralised power generation. Small-scale wind power has seen significant growth in the last ten years, partly due to the political support for renewable energy and the introduction of Feed In Tariffs, which pay home owners for generating their own electricity. Due to their ability to respond quickly to changing wind conditions, small-scale vertical axis...

  13. NASA-Ames vertical gun

    Science.gov (United States)

    Schultz, P. H.

    1984-01-01

    A national facility, the NASA-Ames vertical gun range (AVGR) has an excellent reputation for revealing fundamental aspects of impact cratering that provide important constraints for planetary processes. The current logistics in accessing the AVGR, some of the past and ongoing experimental programs and their relevance, and the future role of this facility in planetary studies are reviewed. Publications resulting from experiments with the gun (1979 to 1984) are listed as well as the researchers and subjects studied.

  14. Industrial Chain: Industrial Vertical Definition

    Institute of Scientific and Technical Information of China (English)

    YifeiDu; GuojunJiang; ShimingLi

    2004-01-01

    Like value chain and supply chain, “industrial chain” becomes the focus of attention. The implication of “industrial chain” has gained a large range of extension. It not only expresses the industrial “chain” structure and relationship of “back and forward”in order or “up and down” in direction, but also it represents a cluster of large scale of firms in an area or colony. It is a network, or a community. Consequently, we conclude that “industrial chain” is a synthesis of industrial chain, industrial cluster, or industrial network.In this article, firstly we will distinguish industry chain from industry. An industry is the collection of firms that have the same attribute, so an industry can be defined by firm collection of certain attribute. We indicate that industrial chain is a kind of vertical and orderly industrial link. It is defined according to a series of specific product or service created. Secondly we analyze the vertical orderly defiinition process from the aspects of social division of labor and requirement division, self-organization system, and value analysis.Non-symmetry and depending on system or community of large scale of industrial units lead to entire industry to “orderly” structure. On the other hand, the draught of diversity and complexity of requirement simultaneously lead to entire industry to be more “orderly”. Along with processes of self-organization, industrial will appi'oach the state of more orderly and steady, and constantly make industrial chain upgrade. Each firm or unit, who will gain the value, has to establish channels of value, which we called “industrial value chain”. Lastly,we discuss the consequence of vertical and orderly definition, which is exhibited by a certain relationship body. The typical forms of industrial chain include industrial cluster, strategy alliance and vertical integration etc.

  15. Poligonación Vertical

    Directory of Open Access Journals (Sweden)

    Esteban Dörries

    2016-03-01

    Full Text Available La poligonación vertical es un método de medición de diferencias de altura que aprovecha las posibilidades de las estaciones totales. Se presta fundamentalmente para líneas de nivelación entre nodos formando red. El nombre se debe a que las visuales sucesivas se proyectan sobre aristas verticales en lugar de un plano horizontal, como ocurre en la poligonación convencional.

  16. Measurement of Eccentricity of the Centre of Mass from the Geometric Centre of a Sphere

    Institute of Scientific and Technical Information of China (English)

    郭俊起; 胡忠坤; 顾邦明; 罗俊

    2004-01-01

    The eccentricity of the centre of mass from the geometric centre of a spherical attracting mass in determining the Newtonian gravitational constant G is tested by means of an electronic balance. The experimental result shows that the eccentricity of the sample is about 0.31 μm with uncertainty of 0.05 μm. Two density distribution models are discussed to estimate the uncertainty to G by the eccentricities of the attracting masses.

  17. Vertical dispersion of oil droplets

    International Nuclear Information System (INIS)

    A mathematical model which predicts oil droplet mixing by breaking waves is presented. Oil spills pose a significant threat to marine and near-shore environments. The spilled oil forms a thin layer on the water surface where breaking waves cause the oil to mix vertically into the water column. The motion of the droplets plays a vital role in the oil mass exchange between the oil slick and the water column. The oil-water interfacial tension coefficient can be reduced with chemical dispersants, which promote the production of smaller droplets with weaker rising velocities compared to the mixing force of turbulence. This newly developed model uses a kinetic approach to describe vertical exchange of droplets at the interface between the water column and the oil slick. General mass conservation principles are satisfied by balancing the mass of oil between the slick and the mixing layer of the water column. This model makes it possible to quickly estimate the amount of dispersed oil under breaking waves. Future work will focus on parameterizing the impact of breaking waves on the vertical mixing of oil droplets to be used in a three-dimensional oil spill model. 31 refs., 6 figs

  18. Wireless Power Transmission

    Directory of Open Access Journals (Sweden)

    Pragati S. Chawardol

    2014-12-01

    Full Text Available A great concern has been voiced in recent years over the extensive use of energy, the limited supply of resourses, and the pollution of the environment from the use of present energy conversion systems. Electrical power accounts for much of the energy consumed. One of the major issue in power system is the losses occurs during the transmission and distribution of electrical power. As the demand increases day by day, the power generation increases and the power loss is also increased. The major amount of power loss occurs during transmission and distribution. The resistance of the wire used in the electrical grid distribution system causes a loss of 26-30% of the energy generated. This loss implies that our present system of electrical distribution is only 70-74% efficient. The above discussed problem can be solved by choose an alternative option for power transmission which could provide much higher efficiency, low transmission cost and avoid power theft. Wireless power transmission is one of the promising technologies and may be the righteous alternative for efficient power transmission. This paper focuses on the past and future possible advancements in WPT. Also the proposed method and technologies in WPT that will make the loss of energy during transmission and distribution to minimum are discussed. Keyword

  19. JOB CENTRE FOR DOMESTIC STAFF IN SWITZERLAND

    CERN Multimedia

    Relations with the Host States Service; http://www.cern.ch/relations/

    2001-01-01

    The Permanent mission of Switzerland to the International Organisations in Geneva has informed CERN that the Geneva Welcome Centre has set up an employment registration desk for the domestic staff of international civil servants. The aim of this pilot project is, on the one hand, to help international civil servants find domestic staff and, on the other hand, to help domestic staff holding an 'F'-type carte de légitimation find employment within 30 days after the expiry of a contract. For more information, please contact the Geneva Welcome Centre, La Pastorale, 106, route de Ferney, Case postale 103, 1211 Genève 20, tel. (+41.22) 918 02 70, fax (+41.22) 918 02 79), http://geneva-international.org/Welcome.E.html.

  20. Danish Polymer Centre annual report 2001

    DEFF Research Database (Denmark)

    Hassager, O.; Hvilsted, S.; Mortensen, Kell

    campus in Lyngby as shown in the pictures on this page. In addition to well equipped laboratories at Risø which will be expanded in 2002 and 2003, thesefacilities provide a common ground for polymer chemists, polymer physicists, chemical engineers and mechanical engineers from the two institutions. The......The centre is a collaboration between the Risø National Laboratory and the Technical University of Denmark (DTU). At the DTU the Department of Chemical Engineering and the Department of Manufacturing Engineering and Management participate in the centre.From 2001 the Polymer Department at Risø...... coordinates the activities at Risø From the outset it was considered important with common laboratories to obtain the full effect of the collaboration between the two departments at the DTU and Risø NationalLaboratory. In 2001 new laboratories for polymer research and education were established at the DTU...

  1. Patient-centred Prevention among PAD Patients

    DEFF Research Database (Denmark)

    Pii, Kathrine Hoffmann

    2014-01-01

    Intro: This paper discusses a central professional dilemma in patient-centred education: on one hand the concern for ensuring patients autonomy and right to make their own decisions regarding their treatment and, on the other hand, a concern for getting patients to make the “right” decisions that...... will improve their health condition. The patient-centred approach (and related concepts: patient participation, involvement, and empowerment) is being promoted both in healthcare politics and by healthcare professionals as a way to achieve more active self-managing and self-caring patients. Patient......-centredness is thus promoted as a way to organize health more effectively (in terms of cost and treatment outcomes) and as a way to ensure patients’ autonomy and fundamental right to make their own decisions regarding their treatment. Critical voices within social and nursing theory have however argued that the...

  2. It's all change at the Computer Centre

    CERN Multimedia

    Laëtitia Pedroso

    2011-01-01

    The IT and EN Departments are modernising the infrastructure of the Computer Centre to improve the conditions in which the equipment has to operate and to increase capacity. The construction work has already begun and is due to be completed in October 2012.   Every year CERN experiences around ten power cuts lasting from less than a second to several hours. In most cases the two protection systems - the UPS* and the diesel generators – are able to ensure that the operation of the Computer Centre is not affected. As Vincent Doré, the project leader for the IT Department, and Paul Pepinster, the EN Department's technical coordinator in charge of modernising the infrastructure, explains: "Building 513 has two types of computing facilities – the "non-critical" ones, such as the servers for "off-line" computing, which have UPS systems ensuring that they can operate for 10 minutes after a power cut, and the "critical&...

  3. Has Trade any Importance in the Transmission of Currency Shocks?

    OpenAIRE

    Roberta De Santis

    2004-01-01

    The object of this study is to assess the role of trade in the transmission of currency shocks across geographically close countries. The analysis will focus on identifying and comparing the degree of vulnerability of new EU member states from the Central and Eastern European countries (CEECs) to currency shocks. We interpret the interactions that a centre-periphery model identifies for periphery countries as a possible description of existing interdependencies among CEECs. According to the c...

  4. Display-centred applications in ubiquitous computing

    OpenAIRE

    José, Rui; Pinto, Helder

    2006-01-01

    Public displays can play an important enabling role in ubiquitous computing environments. This paper describes an on-going work for a multipurpose, multi-display infrastructure, designed to address the requirements of display-centred applications in ubiquitous computing environments. The system provides an infrastructure in which situated displays can act as portals to the physical space, allowing ubicomp applications to support their association with the physical world by providing them with...

  5. Training science centre Explainers. The Techniquest experience

    Directory of Open Access Journals (Sweden)

    Colin Johnson

    2005-12-01

    Full Text Available Techniquest was established in 1986, and in 1995 moved to its current premises at Cardiff Bay, South Wales. This was the first purpose-built science centre in the UK. It receives around 200,000 visitors every year to its exhibition, and to its programmes for schools and public audiences in the theatre, laboratory, discovery room and planetarium. The author joined the Techniquest project in 1985, became a staff member in 1990 and was the Chief Executive from 1997 until his retirement in 2004. Techniquest has three “out-stations” in Wales, and is responsible for the supply and maintenance of exhibits to the Look Out Discovery Centre in Bracknell, England. There is a Techniquest gallery at the Lisbon Pavilhão do Conhecimento - Ciência Viva, and a traveling exhibition, SciQuest, in South Africa which was also supplied by Techniquest. All these centres rely on the effective intervention of “Explainers” (at Techniquest we call them “Helpers” to provide the best possible experience for visitors. At its most demanding, the tasks of an Explainer are varied and intensive, yet there may be times when the duties are mundane or even dull. When you rely on people to act as both hosts and housekeepers, to provide both support and stimulus, and to be both welcoming and watchful, you are asking a great deal. This article raises some of the issues concerned with the recruitment and retention of Explainers, their training and management, and the way in which their role is recognized and valued by the science centre as a whole.

  6. CMS Centres Worldwide - a New Collaborative Infrastructure

    CERN Document Server

    Taylor, Lucas

    2011-01-01

    Webcasts, and generic Web tools such as CMS-TV for broadcasting live monitoring and outreach information. Being Web-based and experiment-independent, these systems could easily be extended to other organizations. We describe the experiences of using CMS Centres Worldwide in the CMS data-taking operations as well as for major media events with several hundred TV channels, radio stations, and many more press journalists simultaneously around the world.

  7. Learning Styles of Independent Learning Centre Users

    OpenAIRE

    Tarik Uzun

    2014-01-01

    Learning style research has been a significant field within language teaching and learning. There have been very few attempts, however, to seek possible links between independent learning and learning style preferences. This paper aims to identify the learning styles of students who use the Independent Learning Centre (ILC) on a regular basis at a state university in Turkey (n=102). The findings of the learning style analysis revealed that, contrary to expectations, most of the regular users ...

  8. The Researcher : The Refugee Documentation Centre Newsletter

    OpenAIRE

    Ahmed, Elisabeth; Goggins, David

    2014-01-01

    Contents: Subsidiary Protection – a distinct and autonomous form of complementary protection / Enda O’Neill, Jennifer Higgins, UNHCR Ireland; Recent Changes at the Refugee Appeals Tribunal / Barry Magee, Refugee Appeals Tribunal; The Use of Decision Templates for Refugee Status Determination / Seán O’Connell, Refugee Appeals Tribunal; Forced Marriage in Afghanistan / David Goggins, Refugee Documentation Centre; Houses of the Holy: Iraq and the last days of the Mandeans / Patrick Dowling, R...

  9. Structure and Responsibilities of Radiation Protection Centre

    International Nuclear Information System (INIS)

    Constitution of Radiation Protection Centre (RPC) in Lithuania is presented. RPC was established in 1997, in 1999 the Government granted the status of the regulatory authority of Lithuania on radiation protection issues. Currently there are two departments at RPC: two in Vilnius - Department of Radiation Protection Supervision and Control and Department of Programs and Expertise, and four in the districts. Main tasks of RPC are listed

  10. Introducing the PET Centre Bydgoszcz - Poland

    International Nuclear Information System (INIS)

    Opening the PET station held 26th February, 2003 was an excellent opportunity to present Regional Centre of Oncology in Bydgoszcz, the city in northern Poland. Department of Nuclear Medicine and its building, equipment, CT/PET station and scanning parameters, the cyclotron with basic technical data have been shortly described. A future of PET diagnostics in Poland taking into account the economical factors has been also discussed

  11. The Elusiveness of Learner-centred Teaching

    OpenAIRE

    Kovačević, Ervin; AKBAROV, Azamat

    2016-01-01

    This research will explore teaching styles of university professors. Teaching style is an umbrella term for teaching decisions made during the entire teaching process – planning, delivery, and evaluation. Contemporary university teachers are advised to adopt the learner-centred teaching style which is assumed to produce remarkable possibilities. In the Fall Semester 2015 fifty-two respondents in different faculties of International University of Sarajevo were surveyed using The Principles of ...

  12. Bismuth centred magnetic perovskite: A projected multiferroic

    International Nuclear Information System (INIS)

    In recent time substantial attention has been initiated to understand the physics behind multiferroism and to design new multiferroic materials. BiMnO3 and BiFeO3 are the well-studied Bi-centred multiferroic oxides. BiMnO3 is a ferromagnetic–ferroelectric (metastable) phase and require drastic conditions to synthesize. However, lanthanum substituted BiMnO3 phases stabilized at ambient pressure. It is thus of major importance to increase the number of ferromagnetic perovskites with Bi cations that could be designed under ambient conditions. In this article, we have presented an up to date report of investigations on Bi-centred magnetic perovskites, a prospective material for multiferroic application. Central focus is concentrated on La0.5Bi0.5MnO3 perovskite with various substitutions at different levels. A few of these perovskites are found to be of practical importance e.g. La0.5Bi0.5Mn0.67Co0.33O3 with high dielectric permittivity coupled with ferromagnetism. A comprehensive analysis of different physical functionalities and their interrelation for a wide range of compositions of these Bi-centred perovskites is presented. It has been found that the complex magnetic behaviour originates from mixed valence metal ions. The ferroelectricity is associated with the 6s2 lone pair of Bi3+ cations. The magnetic ground state influences the dielectric properties reflecting the multiferroism in a single material. - Highlights: • Multiferroics have attracted increasing attention due to their possible device applications. • Bismuth centred magnetic perovskite is one kind of such promising multiferroic materials. • Ferromagnetic Bi-perovskites, which are synthesized at ambient conditions, have been discussed

  13. Shielding design for ETOILE hadron therapy centre

    International Nuclear Information System (INIS)

    The Ion Beam Applications Company is developing a compact superconducting cyclotron for hadron therapy able to deliver various ion beams with an energy of 400 MeV per nucleon and proton beams with an energy of 260 MeV. This system is being proposed to equip ETOILE hadron therapy centre in Lyon. Shielding design based on PHITS and MCNPX Monte Carlo simulation codes is presented, together with some performance figures for the energy degrader. (authors)

  14. Benefits of Reliability Centred Asset Management

    OpenAIRE

    Hilber, Patrik; Wallnerström, Carl Johan; Rosenlind, Johanna; Babu, Sajeesh; Westerlund, Per

    2013-01-01

    This paper provides an overview of risk and reliability assessment techniques, some which are available for distribution system operators, and others that are in the process of development. The main contribution of this paper is showing the possibilities and benefits of detailed risk and reliability analysis. Six samples of findings from research developed over the last decade within the RCAM group (Reliability Centred Asset Management) at the Royal Institute of Technology, Stockholm Sweden, ...

  15. LSE centre for economic performance: bankers’ bonuses

    OpenAIRE

    Bell, Brian

    2010-01-01

    A new series of Election Analyses is now available from the LSE’s Centre for Economic Performance (CEP). The series will discuss the research evidence on some of the key policy battlegrounds of the 2010 General Election, including macroeconomic policy, immigration, health, education, crime, poverty and inequality, labour market policy, regional policy, energy and the environment, financial regulation and bankers’ bonuses, and foreign aid. The latest CEP Election Analysis, by Brian Bell, g...

  16. Mathematical modelling of Regional Fuel Cycle Centres

    International Nuclear Information System (INIS)

    The concept of Regional Fuel Cycle Centres (RFCC) has attracted wide interest as a possible approach towards meeting the nuclear fuel cycle needs of many countries. As part of its study of the RFCC concept, the International Atomic Energy Agency is developing mathematical models and associated computer codes to analyse the economics and logistics of various strategies for management of spent nuclear fuel and waste materials. (author)

  17. The LifeWatch Service Centre Plan

    OpenAIRE

    Parr, Terry; Spinelli, Oliviero; Mauri, Maria Paola; Billisari, Livia; Hardisty, Alex; Ludlow, David; Khan, Zaheer; Roberts, Dave; Sleep, Chris; Sier, Andrew

    2011-01-01

    This report summarises the construction plan for the Lifewatch Service Centre. The main purpose of LifeWatch is to serve the biodiversity and ecosystem research community in its work on the understanding and rational management of our ecosystems for use by policy makers, resource managers, the private sector and the general public. To do this the LifeWatch infrastructure will provide capabilities to analyse, model and simulate with integrated biodiversity and ecosystem data from many dive...

  18. Studies of the CNESTEN's Nuclear Research Centre

    International Nuclear Information System (INIS)

    The different steps of the methodology applied to the site selection of Maamora's Nuclear Research Centre, within a 20 km wide coastal band preliminarily fixed between Kenitra and Casablanca cities, are outlined: delimitation of potential zones, identification of potential sites, selection of preferred sites. A particular attention is given to the criterium of the methodology applied to the preferred sites classifying. 1 map, 2 tabs, 2 refs. (F.M.)

  19. Imperial College Reactor Centre annual report. 1983

    International Nuclear Information System (INIS)

    It is reported that the reactor operated reliably during the year with less than half a day of operating time lost by faults or failures. Brief accounts of the 34 research projects at the Centre are given, and a list of teaching experiments or visits is included. These include undergraduate and post-graduate teaching. Commercial requests for irradiations and neutron activation analysis are reported as increasing. (U.K.)

  20. Stability of some centres in quartz

    OpenAIRE

    Falguères, Christophe; Yokoyama, Yuji; Miallier, Didier

    1991-01-01

    Electron spin resonance (ESR) is a promising dating method for Quaternary sediments. A preliminary ESR analysis was done on quartz grains extracted from sediments baked by lava-flows of Massif Central (France). For this type of sample, zeroing occurs during heating. To test the reliability of the method, the palaeodoses were determined from centres (Al and Ti) and compared with those obtained by the thermoluminescence (TL) method.The annealing temperature and sunlight have an effect upon the ...

  1. Swasti: An International Health Resource Centre

    OpenAIRE

    N. S. Kumar

    2013-01-01

    Swasti, an International Health Resource Centre was established in 2002 in India. The objective was to enhance the health and well-being of communities, particularly the marginalized. Swasti’s main focus lies in the areas of primary health, sexual and reproductive health including HIV, communicable and non-communicable diseases, water, sanitation and hygiene and gender based violence. The organization, during the last decade has grown in leaps and bounds reaching out to the most affected comm...

  2. Lift Augmentation for Vertical Axis Wind Turbines

    Directory of Open Access Journals (Sweden)

    Gerald M Angle II

    2010-12-01

    Full Text Available The concept of harnessing wind power has been around for centuries, and is first recorded by the Persians in 900 AD. These early uses of wind power were for the processing of food, particularly grinding grains, and consisted of stationary blades around a horizontal axis, the precursor to today’s horizontal axis wind turbines (HAWT. Technology for these wind mills was essentially the same until the 1930’s when advances in aircraft propeller theories were applied to the blades of the turbine. During this development period, which has since remained basically unchanged, the design push was for increasingly larger propellers requiring heavy and costly transmissions, generators, and support towers to be installed. An alternative concept to the HAWT was developed by Georges Darrieus [5], which utilized a vertical shaft and is known as a vertical axis wind turbine (VAWT. The scientific development of the concept did not gain strong attention until the 1970’s due to the perceived low efficiency of this style. This perception was due in part to the portion of the blade’s rotary path that is adverse to the generation of power. This efficiency loss can be minimized by the mechanical movement of the blade, relative to the airflow during the upwind portion of the blades’ rotational path. Since, circulation control can alter the forces generated by an airfoil, it could be used to increase the efficiency of a VAWT by increasing the torque produced on the downwind portion of the path, while removing the need for a physical change in angle of attack. With the recent upturn in petroleum costs and global warming concerns, interest in renewable energy technologies have been reinvigorated, in particular the desire for advanced wind energy technologies, including the application of lift augmentation techniques. One of these techniques is to utilize circulation control to enhance the lifting capacity of the blades based on the location of the blade in the

  3. Understanding Ebola Virus Transmission

    Directory of Open Access Journals (Sweden)

    Seth Judson

    2015-02-01

    Full Text Available An unprecedented number of Ebola virus infections among healthcare workers and patients have raised questions about our understanding of Ebola virus transmission. Here, we explore different routes of Ebola virus transmission between people, summarizing the known epidemiological and experimental data. From this data, we expose important gaps in Ebola virus research pertinent to outbreak situations. We further propose experiments and methods of data collection that will enable scientists to fill these voids in our knowledge about the transmission of Ebola virus.

  4. Upcoming opening of CERN's new Mobility Centre

    CERN Multimedia

    2016-01-01

    On 29 February, CERN’s brand new Mobility Centre opened in the Globe car park. The Centre has been created to cater to the transport needs of everyone at CERN, to simplify procedures and to centralise all the transport services on offer: the rental of CERN bikes and cars, the CERN car-sharing scheme and SIXT car rental.   From 29 February onwards, the Mobility Centre in the Globe car park will be the place to go for all your duty travel needs: rental of CERN cars (with or without the CERN logo), SIXT car rental, CERN bike rental, distribution of cards allowing the use of CERN’s self-service bike- and car-sharing schemes. That same day, the premises currently housing the Car Pool in Building 130 will become the CERN garage, responsible for: upkeep and repairs on CERN bikes, minor maintenance work on CERN vehicles (e.g. replacing windscreen wipers, bulbs and fuses, refilling windscreen washer fluid, pumping up tyres, etc.), arranging and following up the repair and maintenan...

  5. INFOTERM – Information Disseminating Centre for Terminology

    Directory of Open Access Journals (Sweden)

    Albina Auksoriūtė

    2014-12-01

    Full Text Available International Information Centre for Terminology (INFOTERM was founded in 1971 by contract with the United Nations Educational, Scientific and Cultural Organization (UNESCO and the Austrian Standards Institute (ASI. In 1996, INFOTERM was reorganized and established as an independent non-profit organization. INFOTERM promotes and supports the cooperation of existing and the establishment of new terminology centres and networks with the general aim to improve domain communication, knowledge transfer and provision of content with view to facilitating the participation of all in the global multilingual knowledge society. The article presents not only a history of the foundation of INFOTERM, the tasks and activities of INFOTERM and its members, which are international, regional or national terminology institutions, organizations and networks, as well as specialized public or semi-public or other non-profit institutions engaged in terminological activities, but also analyses “Guidelines for terminology policies”, preparied by INFOTERM, and cooperation between INFOTERM and the Institute of the Lithuanian Language.In conclusion, the experience and sharing expertise of INFOTERM regarding harmonized methods and guidelines for terminology management and policies, the management of terminology centres, terminology standardization, the use of terminological data, methods and tools in all applications etc are very important for all countries and language communities especially for countries and language communities with less mature terminologies. The Institute of the Lithuanian Language as a member of INFOTERM has a possibility to get information on terminology research and training, terminology publications, terminological events and activities all over the world.

  6. A new visitor centre for CMS

    CERN Multimedia

    2001-01-01

    At the inauguration of the new CMS visitor centre. The CMS experiment inaugurated a new visitor centre at its Cessy site on 14 June. This will allow the thousands of people who come to CERN each year to follow the construction of one the Laboratory's flagship experiments first-hand. CERN receives over 20,000 visitors each year. Until recently, many of them were taken on a guided tour of one of the LEP experiments. With the closure of LEP, however, trips underground are no longer possible, and the Visits' Service has put in place a number of other itineraries (Bulletin 46/2000). Since the CMS detector will be almost entirely constructed in a surface hall, it is now taking a big share of the limelight. The CMS visitor centre has been built on a platform overlooking CMS construction. It contains a set of clear descriptive posters describing the experiment, along with a video projection showing animations and movies about CMS construction. In the coming weeks, a display of CMS detector elements will be added, as...

  7. Gamma Rays frim the Galactic Centre

    CERN Document Server

    Erlykin, A D

    2007-01-01

    Recent results from the HESS gamma ray telescope have shown the presence of both a diffuse, extended, flux of gamma rays above ~0.4 TeV and discrete sources in and near the Galactic Centre. Here, we put forward a possible explanation in terms of the diffusion of cosmic ray protons from a succession of supernova remnants (SNR) in the SgrA* region of the Galaxy plus a contribution from SNR in the rest of the Galactic Centre Region, to be called the Galactic Centre Ridge (GCR). Protons are favoured over electrons because the mG magnetic fields in the Region will attenuate energetic electrons severely. Prominent features are the need for 'anomalous diffusion' of the protons in the whole region and the adoption of low efficiency for SNR acceleration in the high density regions. The latter is related by us to the well-known low 'cosmic ray gradient' in the Galaxy. A corroborating feature is the close correlation of inferred cosmic ray intensity with the smoothed intensity of 5 GHZ radio radiation. We attribute this...

  8. [Vertical fractures: apropos of 2 clinical cases].

    Science.gov (United States)

    Félix Mañes Ferrer, J; Micò Muñoz, P; Sánchez Cortés, J L; Paricio Martín, J J; Miñana Laliga, R

    1991-01-01

    The aim of the study is to present a clinical review of the vertical root fractures. Two clinical cases are presented to demonstrates the criteria for obtaining a correct diagnosis of vertical root fractures. PMID:1659859

  9. Vertical separation of the two beams

    Energy Technology Data Exchange (ETDEWEB)

    Heifets, S.

    1985-10-01

    The author discusses the problem of design of insertion points on the SSC, and in particular keeping the length necessary for them under control. Here he considers the possibility of having vertically separated beams, without a vertical dispersion suppressor.

  10. Prediction of transmissivity of the intervening atmosphere for infrared signature studies

    Science.gov (United States)

    Mahulikar, Shripad P.

    This paper outlines a quick method of estimating the transmissivity of the intervening atmosphere (between the infrared detector and the object to be detected - aircraft/missile), for vertical and slant beams of infrared radiation. The data needed is the transmissivity for horizontal beams of infrared radiation, of a given length, at various altitudes. The intervening atmosphere is discretized into regions of contstant extinction coefficients, and the tranmissivities of these regions are multiplied together to find the transmissivity of the intervening atmosphere.

  11. Tractor Transmissions. A Teaching Reference.

    Science.gov (United States)

    American Association for Agricultural Engineering and Vocational Agriculture, Athens, GA.

    The manual was developed as a reference for teaching students about transmissions in farm tractors. The manual is divided into five sections: (1) transmission history, (2) gears and bearings in transmission, (3) sliding-gear transmissions, (4) planetary gearing, and (5) glossary. The working principles of the sliding-gear transmission, the most…

  12. Transmissions in vehicles 2010

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    Within the international VDI congress 'Gears in vehicles 2010' of the VDI Wissensforum GmbH (Duesseldorf, Federal Republic of Germany) between 22nd and 23rd June, 2010, in Friedrichshafen (Federal Republic of Germany), the following lectures were held: (1) 8HP70H - The moldhybrid transmission from ZF - Cjallenges and achievements (P. Gutmann); (2) GETRAG boosted range extender - A highly flexible electric powertrain for maximum CO{sub 2} reduction (S. Huepkes); (3) E-Transmission between full-hybrid and E-drive (P. Tenberge); (4) Reducing NO{sub x} and particulate emissions in electrified drivelines (R. Kuberczyk); (5) Simulation aided HEV and EV development: from the component to the whole powertrain (A. Gacometti); (6) Investigations on operating behaviour of the optimized CVT hybrid driveline (B.-R. Hoehn); (7) Customer-oriented dimensioning of electrified drivetrains (M. Eghtessad); (8) Decentralized optimal control strategy for parallel hybrid electric vehicles (A. Frenkel); (9) The new generation 6-speed automatic transmission AF40 (G. Bednarek); (10) Customized mechatronic solutions for integrated transmission control units (M. Wieczorek); (11) The optimal automatic transmission for front-transverse applications - Planetary transmissions or dual clutch transmissions? (G. Gumpoltsberger); (12) The new shift-by-wire gearshift lever for the Audi A8 - Requirements and concept (T. Guttenbergere); (13) The new shift-by-wire gearshift lever for the Audi A8 - Realization (A. Giefer); (14) Fuel-efficient transmissions of the future: Calculation of the efficiency factor for vehicle transmissions (B. Volpert); (15) HT-ACM: A new polymer generation for static and dynamic gearbox sealing solutions (E. Osen); (16) 'Energy efficiency equipped solutions by SKF' for power train applications - A contribution to CO{sub 2} - emission reduction and sustainability (T. Bobke); (17) 6-Ratio planetary shift transmission controlled by 4 external brakes, and design

  13. IAEA establishes International Seismic Safety Centre

    International Nuclear Information System (INIS)

    Full text: The IAEA today officially inaugurated an international centre to coordinate efforts for protecting nuclear installations against the effects of earthquakes. The International Seismic Safety Centre (ISSC), which has been established within the IAEA's Department of Nuclear Safety and Security, will serve as a focal point on seismic safety for nuclear installations worldwide. ISSC will assist countries on the assessment of seismic hazards of nuclear facilities to mitigate the consequences of strong earthquakes. 'With safety as our first priority, it is vital that we pool all expert knowledge available worldwide to assist nuclear operators and regulators to be well prepared for coping with major seismic events,' said Antonio Godoy, Acting Head of the IAEA's Engineering Safety Section and leader of the ISSC. 'The creation of the ISSC represents the culmination of three decades of the IAEA's active and recognized involvement in this matter through the development of an updated set of safety standards and the assistance to Member States for their application.' To further seismic safety at nuclear installations worldwide, the ISSC will: - Promote knowledge sharing among the international community in order to avoid or mitigate the consequences of extreme seismic events on nuclear installations; - Support countries through advisory services and training courses; and - Enhance seismic safety by utilizing experience gained from previous seismic events in member states. The centre is supported by a scientific committee of high-level experts from academic, industrial and nuclear safety authorities that will advise the ISSC on implementation of its programme. Experts have been nominated from seven specialized areas, including geology and tectonics, seismology, seismic hazard, geotechnical engineering, structural engineering, equipment, and seismic risk. Japan and the United States have both contributed initial funds for creation of the centre, which will be based at

  14. Addressing the challenges of patient-centred design

    Directory of Open Access Journals (Sweden)

    Karen LaBat

    2009-11-01

    Full Text Available Patient-centred design is a relatively new term, but a longstanding concept in clinical practice. This discussion looks at patient-centred design and explores the relationships of patient-centred design to universal design, user-centred design and the newer human-centred design. It also explores why interdisciplinary approaches are needed for patient-centred design and how interdisciplinary collaboration works to address the challenges of patient centred design. Successful patient-centred solutions can grow from collaborations which include shared visions, understanding of both the nature and degree of variation in the patient,materials, and the designed solution, clear regular communication among all parties with careful definition of terms, and respect for the inherent cultures of all disciplines involved.

  15. Kansas Electric Transmission Lines

    Data.gov (United States)

    Kansas Data Access and Support Center — This data set is a digital representation of the EletcircTransmission lines for the State of Kansas as maintained by the Kansas Corporation Commission. Data is...

  16. Transmission of Flu (Influenza)

    Science.gov (United States)

    ... Skip Content Marketing Share this: Main Content Area Flu (Influenza) Transmission How Flu Spreads Coughing and Sneezing People with flu can ... not be shared without washing thoroughly first. The Flu Is Contagious You may be able to pass ...

  17. Down hole transmission system

    Science.gov (United States)

    Hall, David R.; Hall, Jr., H. Tracy

    2007-07-24

    A transmission system in a downhole component comprises a data transmission element in both ends of the downhole component. Each data transmission element houses an electrically conducting coil in a MCEI circular trough. The electrically conducting coil comprises at least two generally fractional loops. In the preferred embodiment, the transmission elements are connected by an electrical conductor. Preferably, the electrical conductor is a coaxial cable. Preferably, the MCEI trough comprises ferrite. In the preferred embodiment, the fractional loops are connected by a connecting cable. In one aspect of the present invention, the connecting cable is a pair of twisted wires. In one embodiment the connecting cable is a shielded pair of twisted wires. In another aspect of the present invention, the connecting cable is a coaxial cable. The connecting cable may be disposed outside of the MCEI circular trough.

  18. Coexistence of Strategic Vertical Separation and Integration

    DEFF Research Database (Denmark)

    Jansen, Jos

    2003-01-01

    This paper gives conditions under which vertical separation is chosen by some upstream firms, while vertical integration is chosen by others in the equilibrium of a symmetric model. A vertically separating firm trades off fixed contracting costs against the strategic benefit of writing a (two-par...

  19. Vertically aligned nanostructure scanning probe microscope tips

    Science.gov (United States)

    Guillorn, Michael A.; Ilic, Bojan; Melechko, Anatoli V.; Merkulov, Vladimir I.; Lowndes, Douglas H.; Simpson, Michael L.

    2006-12-19

    Methods and apparatus are described for cantilever structures that include a vertically aligned nanostructure, especially vertically aligned carbon nanofiber scanning probe microscope tips. An apparatus includes a cantilever structure including a substrate including a cantilever body, that optionally includes a doped layer, and a vertically aligned nanostructure coupled to the cantilever body.

  20. A design for vertical crossing insertions

    Energy Technology Data Exchange (ETDEWEB)

    Garren, A.

    1985-10-01

    A crossing insertion designed for an SSC with vertically separated 1-in-1 beam lines is presented in this note. The author supposes that the beam lines consist of separate magnets in separate cryostats separated by about 70 cm. He then describes the design, where vertical separation is done with four vertical dipoles producing a steplike beam line.

  1. Gravity wave transmission diagram

    OpenAIRE

    Tomikawa, Y.

    2015-01-01

    A new method of obtaining power spectral distribution of gravity waves as a function of ground-based horizontal phase speed and propagation direction from airglow observations has recently been proposed. To explain gravity wave power spectrum anisotropy, a new gravity wave transmission diagram was developed in this study. Gravity wave transmissivity depends on the existence of critical and turning levels for waves that are determined by background horizontal wind distributio...

  2. Understanding Ebola Virus Transmission

    OpenAIRE

    Seth Judson; Joseph Prescott; Vincent Munster

    2015-01-01

    An unprecedented number of Ebola virus infections among healthcare workers and patients have raised questions about our understanding of Ebola virus transmission. Here, we explore different routes of Ebola virus transmission between people, summarizing the known epidemiological and experimental data. From this data, we expose important gaps in Ebola virus research pertinent to outbreak situations. We further propose experiments and methods of data collection that will enable scientists to fil...

  3. Eliminating Perinatal HIV Transmission

    Centers for Disease Control (CDC) Podcasts

    2012-11-26

    In this podcast, CDC’s Dr. Steve Nesheim discusses perinatal HIV transmission, including the importance of preventing HIV among women, preconception care, and timely HIV testing of the mother. Dr. Nesheim also introduces the revised curriculum Eliminating Perinatal HIV Transmission intended for faculty of OB/GYN and pediatric residents and nurse midwifery students.  Created: 11/26/2012 by Division of HIV/AIDS Prevention.   Date Released: 11/26/2012.

  4. Glutamate Transmission in Addiction

    OpenAIRE

    Kalivas, Peter W.; LaLumiere, Ryan; Knackstedt, Lori; Shen, Haowei

    2008-01-01

    Cortico-striatal glutamate transmission has been implicated in both the initiation and expression of addiction related behaviors, such as locomotor sensitization and drug seeking. While glutamate transmission onto dopamine cells in the ventral tegmental area undergoes transient plasticity important for establishing addiction-related behaviors, glutamatergic plasticity in the nucleus accumbens is critical for the expression of these behaviors. This information points to the value of exploring ...

  5. Continuously Variable Transmission

    Science.gov (United States)

    Grana, D. C.

    1985-01-01

    Chain slides along two cones, in novel transmission concept. Transmission includes chain drive between two splined shafts. Chain sprockets follow surfaces of two cones. As one chain sprocket moves toward smaller diameter other chain sprocket moves toward larger diameter, thereby changing "gear" ratio. Movement initiated by tension applied to chain by planetary gear mechanism. Device positive, simple, and efficient over wide range of speed ratios.

  6. Gravity wave transmission diagram

    Science.gov (United States)

    Tomikawa, Yoshihiro

    2016-07-01

    A possibility of gravity wave propagation from a source region to the airglow layer around the mesopause has been discussed based on the gravity wave blocking diagram taking into account the critical level filtering alone. This paper proposes a new gravity wave transmission diagram in which both the critical level filtering and turning level reflection of gravity waves are considered. It shows a significantly different distribution of gravity wave transmissivity from the blocking diagram.

  7. THE IMPLEMENTATION OF PROFIT CENTRES INSIDE AN ECONOMIC ENTITY

    OpenAIRE

    ADRIAN GROSANU; PAULA RAMONA RACHISAN

    2008-01-01

    The first part of this paper presents, from a conceptual point of view, the responsibility centres and we used a theoretical and methodological approach that allows us to understand the role generally played by the responsibility centres, profit centres in particular, concerning the optimization of economic efficiency of a business. According to the existing particularities of economic entities of the cosmetic industry, we delimited some responsibility centres and identified some of the relat...

  8. National transmission grid study

    Energy Technology Data Exchange (ETDEWEB)

    Abraham, Spencer [USDOE Office of the Secretary of Energy, Washington, DC (United States)

    2003-05-31

    The National Energy Policy Plan directed the U.S. Department of Energy (DOE) to conduct a study to examine the benefits of establishing a national electricity transmission grid and to identify transmission bottlenecks and measures to address them. DOE began by conducting an independent analysis of U.S. electricity markets and identifying transmission system bottlenecks using DOE’s Policy Office Electricity Modeling System (POEMS). DOE’s analysis, presented in Section 2, confirms the central role of the nation’s transmission system in lowering costs to consumers through increased trade. More importantly, DOE’s analysis also confirms the results of previous studies, which show that transmission bottlenecks and related transmission system market practices are adding hundreds of millions of dollars to consumers’ electricity bills each year. A more detailed technical overview of the use of POEMS is provided in Appendix A. DOE led an extensive, open, public input process and heard a wide range of comments and recommendations that have all been considered.1 More than 150 participants registered for three public workshops held in Detroit, MI (September 24, 2001); Atlanta, GA (September 26, 2001); and Phoenix, AZ (September 28, 2001).

  9. ?Vertical Sextants give Good Sights?

    Science.gov (United States)

    Richey, Michael

    Mark Dixon suggests (Forum, Vol. 50, 137) that nobody thus far has attempted to quantify the errors from tilt that arise while observing with the marine sextant. The issue in fact, with the related problem of what exactly is the axis about which the sextant is rotated whilst being (to define the vertical), was the subject of a lively controversy in the first two volumes of this Journal some fifty years ago. Since the consensus of opinion seems to have been that the maximum error does not necessarily occur at 45 degrees, whereas Dixon's table suggests that it does, some reiteration of the arguments may be in order.

  10. Topics in Electricity Transmission Pricing

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerndal, Mette

    2000-02-01

    Directorate (NVE). To prevent cross-subsidization, the largest state-owned firm was split to form Statkraft SF, Norway's largest generation company, and Statnett SF, the major transmission company. Statnett is also the system operator of the entire Norwegian power system. Many distribution companies, usually publicly owned, are still part of vertically integrated companies, but there is strict separation of the financial accounts for transmission/distribution and generation/marketing. Trading is accomplished through several channels. The largest organized market is the common Norwegian-Swedish pool, NordPool. NordPool ASA is owned by Statnett Marked (which is a subsidiary of Statnett) and the Swedish grid-company, Svenska Kraftnaet. NordPool also supports the Finnish and Danish markets, thus through cooperation with the grid-companies of Denmark (Eltra) and Finland (Fingrid), locational markets are provided in these countries as well. Unlike England and Wales, only part of actual production is traded on this market. In addition, independent brokers offer various energy-contracts and facilitate bilateral contracts. In 1998 22% of the energy was traded on the hourly day-ahead (spot) market of NordPool. NordPool also organizes a forward and futures market and settles contracts from the regulation market organized by Statnett. The regulation market is a realtime market used to settle imbalances in real time. In total, close to 30% of the energy traded is organized through NordPool, and this share is increasing year by year. The efficiency of the market is heavily affected by the operation and pricing of the transmission system, and the topic of this thesis concerns the interaction of the transmission network and the energy markets. Throughout, the findings are illustrated by means of simple examples. This is to enhance readability and intuition. To start with, chapter 2 is devoted to power flow models, whereas chapter 3 provides an overview of models developed to efficiently

  11. Topics on Electricity Transmission Pricing

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerndal, Mette

    2000-02-01

    Directorate (NVE). To prevent cross-subsidization, the largest state-owned firm was split to form Statkraft SF, Norway's largest generation company, and Statnett SF, the major transmission company. Statnett is also the system operator of the entire Norwegian power system. Many distribution companies, usually publicly owned, are still part of vertically integrated companies, but there is strict separation of the financial accounts for transmission/distribution and generation/marketing. Trading is accomplished through several channels. The largest organized market is the common Norwegian-Swedish pool, NordPool. NordPool ASA is owned by Statnett Marked (which is a subsidiary of Statnett) and the Swedish grid-company, Svenska Kraftnaet. NordPool also supports the Finnish and Danish markets, thus through cooperation with the grid-companies of Denmark (Eltra) and Finland (Fingrid), locational markets are provided in these countries as well. Unlike England and Wales, only part of actual production is traded on this market. In addition, independent brokers offer various energy-contracts and facilitate bilateral contracts. In 1998 22% of the energy was traded on the hourly day-ahead (spot) market of NordPool. NordPool also organizes a forward and futures market and settles contracts from the regulation market organized by Statnett. The regulation market is a realtime market used to settle imbalances in real time. In total, close to 30% of the energy traded is organized through NordPool, and this share is increasing year by year. The efficiency of the market is heavily affected by the operation and pricing of the transmission system, and the topic of this thesis concerns the interaction of the transmission network and the energy markets. Throughout, the findings are illustrated by means of simple examples. This is to enhance readability and intuition. Chapter 2 is devoted to power flow models, whereas chapter 3 provides an overview of models developed to efficiently coordinate the

  12. Geotechnical assessments of upgrading power transmission lines

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Andrew [Coffey Geotechnics Ltd., Harrogate (United Kingdom)

    2012-11-01

    One of the consequences of increasing demand for energy is a corresponding requirement for increased energy distribution. This trend is likely to be magnified by the current tendency to generate power in locations remote from centres of population. New power transmission routes are expensive and awkward to develop, and there are therefore benefits to be gained by upgrading existing routes. However, this in turn raises problems of a different nature. The re-use of any structure must necessarily imply the acceptance of unknowns. The upgrading of transmission lines is no exception to this, particularly when assessing foundations, which in their nature are not visible. A risk-based approach is therefore used. This paper describes some of the geotechnical aspects of the assessment of electric power transmission lines for upgrading. It briefly describes the background, then discusses some of the problems encountered and the methods used to address them. These methods are based mainly on information obtained from desk studies and walkover surveys, with a limited amount of intrusive investigation. (orig.)

  13. Canadian Educational Development Centre Websites: More Ebb than Flow?

    Science.gov (United States)

    Simmons, Nicola

    2010-01-01

    This paper examines information portrayed on Canadian educational development (ED) centre websites and, in particular, whether information that corresponds to questions compiled from a literature search of ED centre practices is readily available from centre websites. This study phase is part of a larger national study of Canadian educational…

  14. Tele-centres as a way of achieving universal access

    DEFF Research Database (Denmark)

    Falch, Morten; Anyimadu, Amos

    2003-01-01

    The success of tele-centres in Ghana is discussed. The tele-centres offer a low cost opportunity to empower local communities in developed and developing countries to meet the challenges of the information society. The tele-centres can also contribute more directly to the supply of non-commercial...

  15. Implementation of SST-1 plasma position control using vertical field

    International Nuclear Information System (INIS)

    SST-1 (Steady State Superconducting Tokamak) is a plasma confinement device in Institute for Plasma Research (IPR) India. SST-1 has been commissioned successfully and has been carrying out plasma experiments since the beginning of 2014 and achieved a maximum plasma current of 75 kA at a central field of 1.5 T and the plasma duration ∼ 500 ms. After commissioning of first wall components SST-1 looks forward to carrying out elongated plasma experiments and stretching plasma pulses beyond 1sec. The plasma is very unstable in nature. In order to confine it for a longer duration various controls need to be act upon simultaneously. The most important control is the position control. One of the means to control plasma position is by adjusting Vertical Field (VF) which forces plasma to remain in centre of the Tokamak. The SST-1 Plasma control system is a distributed real-time system based on VME architecture. The plasma position and current are computed in real time on Digital Signal Processor (DSP) module and then transmitted to VF power supply controller over Reflective Memory (RFM) based data network where VF coil current is modified based on plasma position drift from the centre. The SST-1 recent campaign shows that real time control of VF enhanced the plasma duration by the order of few msec. This paper focuses on the architecture and implementation aspects of the plasma position feedback control system and presents the initial results observed in recent SST-1 experiment campaign. (author)

  16. Wireless data signal transmission system

    DEFF Research Database (Denmark)

    2014-01-01

    The present invention relates to a method for providing a radio frequency signal for transmission, a system for providing a radio frequency signal for transmission and a method for wireless data transmission between a transmitter and a receiver.......The present invention relates to a method for providing a radio frequency signal for transmission, a system for providing a radio frequency signal for transmission and a method for wireless data transmission between a transmitter and a receiver....

  17. Addiction research centres and the nurturing of creativity The Norwegian Centre for Addiction Research (SERAF).

    Science.gov (United States)

    Bramness, Jørgen G; Clausen, Thomas; Duckert, Fanny; Ravndal, Edle; Waal, Helge

    2011-08-01

    The Norwegian Centre for Addiction Research (SERAF) at the University of Oslo is a newly established, clinical addiction research centre. It is located at the Oslo University Hospital and has a major focus on opioid dependency, investigating Norwegian opioid maintenance treatment (OMT), with special interest in OMT during pregnancy, mortality, morbidity and criminality before, during and after OMT and alternatives to OMT, such as the use of naltrexone implants. The well-developed health registries of Norway are core assets that also allow the opportunity for other types of substance abuse research. This research includes health services, abuse of prescription drugs and drugs of abuse in connection with traffic. The centre also focuses upon comorbidity, investigating the usefulness and limitations of psychometric instruments, drug abuse in different psychiatric treatment settings and internet-based interventions for hazardous alcohol consumption. PMID:20735364

  18. Bhabha Atomic Research Centre: annual report 1988

    International Nuclear Information System (INIS)

    The research and development (R and D) work carried out in the Bhabha Atomic Research Centre (BARC), Bombay during 1988 is summarised and presented in the sections entitled Physical Sciences, Chemical Sciences, Materials and Materials Science, Radioisotopes, Reactors, Fuel cycle, Radiological Safety and Protection, Electronics and Instrumentation, Engineering Services, Life Sciences and General. At the end of each section a list of publications is also given. The R and D work of the outstation units of BARC, namely, Nuclear Research Laboratory, Srinagar; High Altitute Research Laboratory, Gulmarg and Variable Energy Cyclotron Centre, Calcutta are also described in this report. Some of the highlights of the work during the year are: (1) Medium Energy Heavy Ion Accelerator (MEHIA) facility set up jointly by BARC and the Tata Institute of Fundamental Research (TIFR) at TIFR premises became fully operational in September 1988. A number of new compositions of high temperature supconducting materials were synthesized. The highest transition temperature achieved was 125 K. Research work to improve the quality of sintered uranium oxide pellets achieved the purpose. Nuclear fuels were fabricated by using sol-gel process. R and D work for 235 MWe and 500 MWe PHWR type reactors is continuing. Conceptual design of the fuel handling system for the prototype fast breeder reactor was finalised. 233U+Al alloy fuel for Kamini reactor was fabricated. Progress has been made in industrial applications of enzymes. Various applications of radioisotopes are being continued. Certain technologies and processes developed in the Centre were transferred to commercial agencies for large scale exploitation. (M.G.B.)

  19. Human-centred approaches in slipperiness measurement

    Science.gov (United States)

    Grönqvist, Raoul; Abeysekera, John; Gard, Gunvor; Hsiang, Simon M.; Leamon, Tom B.; Newman, Dava J.; Gielo-Perczak, Krystyna; Lockhart, Thurmon E.; Pai, Clive Y.-C.

    2010-01-01

    A number of human-centred methodologies—subjective, objective, and combined—are used for slipperiness measurement. They comprise a variety of approaches from biomechanically-oriented experiments to psychophysical tests and subjective evaluations. The objective of this paper is to review some of the research done in the field, including such topics as awareness and perception of slipperiness, postural and balance control, rating scales for balance, adaptation to slippery conditions, measurement of unexpected movements, kinematics of slipping, and protective movements during falling. The role of human factors in slips and falls will be discussed. Strengths and weaknesses of human-centred approaches in relation to mechanical slip test methodologies are considered. Current friction-based criteria and thresholds for walking without slipping are reviewed for a number of work tasks. These include activities such as walking on a level or an inclined surface, running, stopping and jumping, as well as stair ascent and descent, manual exertion (pushing and pulling, load carrying, lifting) and particular concerns of the elderly and mobility disabled persons. Some future directions for slipperiness measurement and research in the field of slips and falls are outlined. Human-centred approaches for slipperiness measurement do have many applications. First, they are utilized to develop research hypotheses and models to predict workplace risks caused by slipping. Second, they are important alternatives to apparatus-based friction measurements and are used to validate such methodologies. Third, they are used as practical tools for evaluating and monitoring slip resistance properties of foot wear, anti-skid devices and floor surfaces. PMID:11794763

  20. The "Magic" of Tutorial Centres in Hong Kong: An Analysis of Media Marketing and Pedagogy in a Tutorial Centre

    Science.gov (United States)

    Koh, Aaron

    2014-01-01

    Why do more than three-quarters of Hong Kong's senior secondary students flock to tutorial centres like moths to light? What is the "magic" that is driving the popularity of the tutorial centre enterprise? Indeed, looking at the ongoing boom of tutorial centres in Hong Kong (there are almost 1,000 of them), it is difficult not to ask…

  1. Biological Inspiration in Human Centred Robotics

    Institute of Scientific and Technical Information of China (English)

    HU Huo-sheng; LIU Jin-dong; Calderon Carlos A

    2004-01-01

    Human centred robotics (HCR) concerns with the development of various kinds of intelligent systems and robots that will be used in environments coexisting with humans. These systems and robots will be interactive and useful assistants/companions for people in different ages, situations, activities and environments in order to improve the quality of life. This paper presents the autors' current research work toward the development of advanced theory and technologies for HCR applications, based on inspiration from biological systems. More specifically, both bio-mimetic system modelling and robot learning by imitation are discussed respectively, and some preliminary results are demonstrated.

  2. Frequency selectivity at very low centre frequencies

    DEFF Research Database (Denmark)

    Orellana, Carlos Andrés Jurado; Pedersen, Christian Sejer; Marquardt, Torsten

    2010-01-01

    measurements based on OAE suppression techniques and notched-noise masking data psychophysically measured for centre frequencies in the range 50-125 Hz, this study examines how individual differences in frequency selectivity, as well as in masking, may occur at very low CFs due to individual differences in the...... shape of the METFs, thought to be affected by the helicotrema impedance. Preliminary analysis indicates that individual differences in the METFs might underlay the observed individual differences in frequency selectivity. Main effects predicted by the calculations are a pronounced flattening off of the...

  3. STEPS Centre research: our approach to impact

    OpenAIRE

    Ely, Adrian; Oxley, Nathan

    2014-01-01

    The ‘impact’ of research has seen a dramatic rise up the UK’s policy agenda in recent years. But what does ‘impact’ really mean? How do researchers and others respond to the new ‘impact agenda’ and how might we best plan, monitor and report on impact? This working paper attempts to provide answers to some of these questions by reviewing various understandings of ‘impact’ and describing the approach used by the ESRC STEPS Centre in its second five-year phase of funding. In particular, we draw ...

  4. Hunting for hardware changes in data centres

    International Nuclear Information System (INIS)

    With many servers and server parts the environment of warehouse sized data centres is increasingly complex. Server life-cycle management and hardware failures are responsible for frequent changes that need to be managed. To manage these changes better a project codenamed “hardware hound” focusing on hardware failure trending and hardware inventory has been started at CERN. By creating and using a hardware oriented data set - the inventory - with detailed information on servers and their parts as well as tracking changes to this inventory, the project aims at, for example, being able to discover trends in hardware failure rates.

  5. The INTEGRAL science data centre (ISDC)

    DEFF Research Database (Denmark)

    Courvoisier, T.J.L.; Walter, Rasmus; Beckmann, V.;

    2003-01-01

    The INTEGRAL Science Data Centre (ISDC) provides the INTEGRAL data and means to analyse them to the scientific community. The ISDC runs a gamma ray burst alert system that provides the position of gamma ray bursts on the sky within seconds to the community. It operates a quick-look analysis of the...... data within few hours that detects new and unexpected sources as well as it monitors the instruments. The ISDC processes the data through a standard analysis the results of which are provided to the observers together with their data....

  6. Vertical optical ring resonators fully integrated with nanophotonic waveguides on silicon-on-insulator substrates

    CERN Document Server

    Madani, Abbas; Stolarek, David; Zimmermann, Lars; Ma, Libo; Schmidt, Oliver G

    2015-01-01

    We demonstrate full integration of vertical optical ring resonators with silicon nanophotonic waveguides on silicon-on-insulator substrates to accomplish a significant step towards 3D photonic integration. The on-chip integration is realized by rolling up 2D differentially strained TiO2 nanomembranes into 3D microtube cavities on a nanophotonic microchip. The integration configuration allows for out of plane optical coupling between the in-plane nanowaveguides and the vertical microtube cavities as a compact and mechanically stable optical unit, which could enable refined vertical light transfer in 3D stacks of multiple photonic layers. In this vertical transmission scheme, resonant filtering of optical signals at telecommunication wavelengths is demonstrated based on subwavelength thick walled microcavities. Moreover, an array of microtube cavities is prepared and each microtube cavity is integrated with multiple waveguides which opens up interesting perspectives towards parallel and multi-routing through a ...

  7. 2006 Final Transmission Proposal.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    2005-06-01

    This Record of Decision (ROD) contains the decisions of the Administrator of the Bonneville Power Administration BPABPA with respect to the adoption of transmission and ancillary services rates for the two-year rate period beginning October 1, 2005, and ending September 30, 2007 (fiscal years (FY) 2006-2007)(2006 Final Transmission and Ancillary Services Rate Proposal). These decisions are based on the record compiled in this rate proceeding. The transmission and ancillary services rates adopted in this ROD are the rates proposed as a result of a comprehensive settlement agreement between BPA's Transmission Business Line (BPA-TBL) and a diverse group of transmission customers, including BPA's Power Business Line (BPA-PBL), regional investor-owned utilities, partial and full requirements customers of the BPA-PBL, Direct Services Industrial (DSI) customers, and merchant generators. The decisions in this ROD to adopt the rates and charges proposed by the settlement agreement are not intended to create or imply any factual , legal, procedural or substantive precedent, or to create agreement to any underlying principle or methodology.

  8. Structural and Electrical Investigation of C60-Graphene Vertical Heterostructures.

    Science.gov (United States)

    Kim, Kwanpyo; Lee, Tae Hoon; Santos, Elton J G; Jo, Pil Sung; Salleo, Alberto; Nishi, Yoshio; Bao, Zhenan

    2015-06-23

    Graphene, with its unique electronic and structural qualities, has become an important playground for studying adsorption and assembly of various materials including organic molecules. Moreover, organic/graphene vertical structures assembled by van der Waals interaction have potential for multifunctional device applications. Here, we investigate structural and electrical properties of vertical heterostructures composed of C60 thin film on graphene. The assembled film structure of C60 on graphene is investigated using transmission electron microscopy, which reveals a uniform morphology of C60 film on graphene with a grain size as large as 500 nm. The strong epitaxial relations between C60 crystal and graphene lattice directions are found, and van der Waals ab initio calculations support the observed phenomena. Moreover, using C60-graphene heterostructures, we fabricate vertical graphene transistors incorporating n-type organic semiconducting materials with an on/off ratio above 3 × 10(3). Our work demonstrates that graphene can serve as an excellent substrate for assembly of molecules, and attained organic/graphene heterostructures have great potential for electronics applications. PMID:26027690

  9. Prevention and control of carbapenemase-producing organisms at a regional burns centre.

    Science.gov (United States)

    Teare, L; Myers, J; Kirkham, A; Tredoux, T; Martin, R; Boasman, S; Wisbey, A; Charlton, C; Dziewulski, P

    2016-06-01

    In many parts of the world, carbapenemase-producing organisms (CPOs) are endemic. The transfer of medical patients from such countries to the UK requires us to have control systems in place to avoid onward transmission. This report describes the experience of a regional burns centre challenged by its first four cases of CPO in two separate incidents. Key learning from our experience was the importance of CPOs being considered in empirical antibiotics for any patient from an endemic area. Using contact plates, we demonstrated high bacterial counts after cleaning and we describe a terminal cleaning strategy along with the importance of continuing staff engagement and education. PMID:27105751

  10. Clinico-epidemiological profile of malaria: Analysis from a primary health centre in Karnataka, Southern India

    Directory of Open Access Journals (Sweden)

    Ramachandra Kamath

    2013-01-01

    Full Text Available Malaria continues to be a major public health problem in India and worldwide. The present study was based on records from a primary health centre in Karnataka. Morbidity patterns and important features of malaria transmission specific to Udupi district were investigated. The incidence of malaria and various morbidity patterns during 2010 and 2011 were compared and analyzed. Factors such as rapid urbanization, increased construction activities and influx of migratory workers were highlighted as the leading causes for the advent of malaria in the area. Recommendations have been provided for implementation in the near future.

  11. The Australian centre for RF bioeffects research (ACRBR) - an NHMRC centre of research excellence

    International Nuclear Information System (INIS)

    Full text: The Australian Centre for Radiofrequency Bioeffects Research (ACRBR) is a newly established multi-institutional research centre which seeks to research questions pertaining to possible health effects of exposure to radiofrequency devices, such as mobile phones and which is funded under the Australian National Health and Medical Research Council (NHMRC) Centres of Research Excellence funding program. The Centre of Research Excellence in Electromagnetic Energy is combining the efforts of engineers, epidemiologists, physicists, psychophysiologists and veterinary pathologists from RMIT University, the Institute of Medical and Veterinary Science in South Australia (IMVS), Monash University, Swinburne University of Technology and Telstra Research Laboratories (TRL). The centre is funded at $2.5 M over five years and will undertake a program of research to address the issue of exposure to radiofrequency (RF) devices and health. It will also train new scientists, keep the community informed of ongoing developments and help the development of government policies in this area of considerable public concern. The 5-year program has the following components: Neurobiology: One important area where there is a perceived research gap is in the area of potential neurological effects, which will hence be a major focus of this Centre. The proposed studies range from in vitro and in vivo research studies of RF effects on neuron and neural system functioning in rodents, to that of RF effects on simple neural function, cognition and subjective report in humans. The latter series of studies have been developed to account for the consensus view that more emphasis needs to be placed on possible differences in RF population sensitivity (e.g. youth versus aged, and ' electromagnetic hypersensitives'). Epidemiological studies are an important tool in studying the impact on public health from exposure of whole populations to modern radio technologies. Cancer outcomes in this area of

  12. Aerosol Transmission of Filoviruses

    Directory of Open Access Journals (Sweden)

    Berhanu Mekibib

    2016-05-01

    Full Text Available Filoviruses have become a worldwide public health concern because of their potential for introductions into non-endemic countries through international travel and the international transport of infected animals or animal products. Since it was first identified in 1976, in the Democratic Republic of Congo (formerly Zaire and Sudan, the 2013–2015 western African Ebola virus disease (EVD outbreak is the largest, both by number of cases and geographical extension, and deadliest, recorded so far in medical history. The source of ebolaviruses for human index case(s in most outbreaks is presumptively associated with handling of bush meat or contact with fruit bats. Transmission among humans occurs easily when a person comes in contact with contaminated body fluids of patients, but our understanding of other transmission routes is still fragmentary. This review deals with the controversial issue of aerosol transmission of filoviruses.

  13. Aerosol Transmission of Filoviruses.

    Science.gov (United States)

    Mekibib, Berhanu; Ariën, Kevin K

    2016-01-01

    Filoviruses have become a worldwide public health concern because of their potential for introductions into non-endemic countries through international travel and the international transport of infected animals or animal products. Since it was first identified in 1976, in the Democratic Republic of Congo (formerly Zaire) and Sudan, the 2013-2015 western African Ebola virus disease (EVD) outbreak is the largest, both by number of cases and geographical extension, and deadliest, recorded so far in medical history. The source of ebolaviruses for human index case(s) in most outbreaks is presumptively associated with handling of bush meat or contact with fruit bats. Transmission among humans occurs easily when a person comes in contact with contaminated body fluids of patients, but our understanding of other transmission routes is still fragmentary. This review deals with the controversial issue of aerosol transmission of filoviruses. PMID:27223296

  14. Dynamic lung transmission studies

    International Nuclear Information System (INIS)

    The aim of this study was to develop a non-invasive method for determining regional lungvolumes, which could replace bronchospirometry in routine clinical use. Transmission through the thorax of sup(99m)Tc-gammarays is measured by means of a gamma camera on line with a computer. The technique of measurement and data analysis is described and tested in several series of phantom studies. The results proved to be good: the mean difference with the real volumes was -4%. The error varied between -10% and +1. Transmission studies and bronchospirometry are compared in a group of 11 patients and there proved to be a good correspondence between the results of these methods. It is concluded that transmission experiments can determine the vital capacity of both lungs as a whole as accurately as spirometry and allows the measurement of vital capacity for each lung separately with the same accuracy as bronchospirometry. (Auth.)

  15. Information validation tool for technical support centres

    International Nuclear Information System (INIS)

    The French National Emergency Organisation relies on the expert advice given by the different Technical Support Centres (EDF/SEPTEN, CEA/IPSN, Framatome). For several years a great effort has been made to improve tools. The first generation was mainly concerned with computational aids such as real-time plant data acquisition and visualisation, break size calculations, containment release estimations... These tools were presented at the OECD NEA Specialist Meeting in 1993. Currently work is performed in the field of validation of information available to the Technical Support Centres. The three partners (EDF, CEA and Framatome) have developed a prototype implementing the diagnosis and the quality of the information pertaining to the 3D/3P method. The philosophy of this tool is to present to the expert a set of essential information (e.g. state of the fuel barrier, primary water inventory...) for the diagnosis with a confidence level associated to each information and the adequate explications. In fact the expert has not only to know the diagnosis but also how reliable the information is and why. Subsequently, the algorithms used to elaborate the diagnoses and the confidence factor have to be simple enough so that the user is able to consult the explanations in a fast and easy way. The paper details the three-step process to elaborate the diagnosis and the confidence factor

  16. KNMI Data Centre: Easy access for all

    Science.gov (United States)

    van de Vegte, John; Som de Cerff, Wim; Plieger, Maarten; de Vreede, Ernst; Sluiter, Raymond; Willem Noteboom, Jan; van der Neut, Ian; Verhoef, Hans; van Versendaal, Robert; van Binnendijk, Martin; Kalle, Henk; Knopper, Arthur; Spit, Jasper; Mastop, Joeri; Klos, Olaf; Calis, Gijs; Ha, Siu-Siu; van Moosel, Wim; Klein Ikkink, Henk-Jan; Tosun, Tuncay

    2013-04-01

    KNMI is the Dutch institute for weather, climate research and seismology. It disseminates weather information to the public at large, the government, aviation and the shipping industry in the interest of safety, the economy and a sustainable environment. To gain insight into long-term developments KNMI conducts research on climate change. Making the knowledge, data and information on hand at KNMI accessible is one core activity. A huge part of the KNMI information is from numerical models, insitu sensor networks and remote sensing satellites. This digital collection is mostly internal only available and is a collection of non searchable , non standardized file formats, lacking documentation and has no references to scientific publications. With the KNMI Data Centre (KDC) project these issues are tackled. In the project a user driven development approach with SCRUM was chosen to get maximum user involvement in a relative short development timeframe. Building on open standards and proven open source technology (which includes in-house developed software like ADAGUC WMS and Portal) resulted in a first release in December 2012 This presentation will focus on the aspects of KDC relating to its technical challenges, the development strategy and the initial usage results of the data centre.

  17. ALICE opens its new nerve centre

    CERN Multimedia

    Antonella Del Rosso

    2014-01-01

    Twenty-nine fully equipped and ergonomic workstations, one meeting area and 11 large format screens in a completely refurbished room: the ALICE Run Control Centre (ARC) implements the best and newest solutions for its shift workers and expert operators, including access for persons with reduced mobility and very soon a magic window for Point 2 visitors.   The ALICE Run Control Centre. “Our initial intention was just to optimise the old layout,” says Federico Ronchetti from Laboratori Nazionali di Frascati (Italy), a CERN scientific associate currently appointed as ALICE Run Coordinator and person in charge of the ALICE Consolidation Task Force. “However, during the review process, we carried out a study of all the existing control rooms at CERN and became aware we needed a radical change. Hence we started planning a complete redesign of the workspace.” Designed and equipped over many years, the old ALICE control room did not have enough space to fit al...

  18. Pharmacist involvement in a diabetic education centre.

    Science.gov (United States)

    Kanitz, J; Birken, B; Ward, V

    1982-01-01

    During the past two years, a multi-discipline health team has been meeting with selected diabetic "problem" patients on a regular basis at the North York General Hospital (NYGH). The patients are referred to the programme by their physicians when they appear to be having difficulty handling or coping with their diabetes. The participants in the programme attend the Diabetic Education Centre (DEC) for one week as day patients in the hospital and are exposed to various types of counselling from members of the Diabetic Education Centre Team (DECT), one of which is the pharmacist. Follow-up from this week of intensive education is made at annual intervals. The main purpose of the pharmacist in the clinic is to provide information for the patients regarding their prescriptions and over the counter (OTC) medication. This is achieved by means of individual patient interviews and informal group discussions, as well as rounds with other team members and contact with patients' families. This programme provides a forum for the patient and the patient's family to obtain valid information about diabetes, as well as problems associated with the disease, and aids in coping with these problems. The team concept enables the patient to be analyzed by all disciplines in order to assess his teaching needs and fulfill them. The pharmacist is continually involved in this information system and plays a valuable role on the team. PMID:10257341

  19. CMS tracker slides into centre stage

    CERN Multimedia

    2006-01-01

    As preparations for the magnet test and cosmic challenge get underway, a prototype tracker has been carefully inserted into the centre of CMS. The tracker, in its special platform, is slowly inserted into the centre of CMS. The CMS prototype tracker to be used for the magnet test and cosmic challenge coming up this summer has the same dimensions -2.5 m in diameter and 6 m in length- as the real one and tooling exactly like it. However, the support tube is only about 1% equipped, with 2 m2 of silicon detectors installed out of the total 200 m2. This is already more than any LEP experiment ever used and indicates the great care needed to be taken by engineers and technicians as these fragile detectors were installed and transported to Point 5. Sixteen thousand silicon detectors with a total of about 10 million strips will make up the full tracker. So far, 140 modules with about 100 000 strips have been implanted into the prototype tracker. These silicon strips will provide precision tracking for cosmic muon...

  20. Bhabha Atomic Research Centre annual report : 1989

    International Nuclear Information System (INIS)

    The main thrust of the various research and development (R and D) activities of the Bhabha Atomic Research Centre (BARC), Bombay, is towards the implementation of India's nuclear power programme. To that end, its R and D activities cover the entire nuclear fuel cycle, reactor technology; applications of radioisotopes and radiations in agriculture, medicine and industries; and radiation protection in nuclear installations. The report presents in summarised form the R and D activities carried out during 1989 in the chapters entitled: Physical Sciences, Chemical Sciences, Materials and Materials Sciences, Radioisotopes, Reactors, Fuel Cycle, Radiological Safety and Protection, Electronics and Instrumentation, Engineering Services, Life Sciences and General. At the end of each chapter, a list of publications by the staff scientists in the corresponding subject field is given. The list includes published journal articles and technical reports, and papers presented at conferences, symposia etc. The report also covers the R and D activities of the outstation units of BARC, namely, Nuclear Research Laboratory, Srinagar; High Altitude Research Laboratory, Gulmarg; and Variable Energy Cyclotron Centre, Calcutta. BARC is also engaged in basic an applied research in frontier areas of science such as plasma and fusion physics, accelerators and lasers, high temperature superconductivity, condensed matter physics, high pressure physics, high resolution spectroscopy, chemical reaction dynamics and laser induced chemistry, electronics and robotics: radiation biology, and genetic engineering. Report is illustrated with a number of figures, graphs, and coloured pictures. (M.G.B.) figs., refs

  1. Enhancing Communication in an Egyptian Research Centre

    International Nuclear Information System (INIS)

    This paper is a proposed attempt to enhance communication in a research centre in Egypt. The currently Nuclear and Radiological Regulatory Authority (NRRA) which formerly was the National Centre for Nuclear Safety and Radiation Control (NCNSRC) is housed in a nine-storey building with a straight double loaded corridor architectural plan. Syntactic axial analysis showed high integration for each floor plan individually which means that the floor plan is not to be blamed for lack of communication among floor inhabitants; other means must be attempted. But global axial integration (for the whole building) proved to be poor. A problem of communication among floors was identified. Means for enhancing communication were introduced: The lecture hall, the cafe and meeting rooms can play an important role in enhancing global communication among NRRA inhabitants. Besides a questionnaire was designed and distributed on all inhabitants and its feedback came up with ideas which if implemented could result in enhancing the level of communication between the inhabitants of the building thus overcoming spatial hindrances.

  2. WISB: Warwick Integrative Synthetic Biology Centre.

    Science.gov (United States)

    McCarthy, John

    2016-06-15

    Synthetic biology promises to create high-impact solutions to challenges in the areas of biotechnology, human/animal health, the environment, energy, materials and food security. Equally, synthetic biologists create tools and strategies that have the potential to help us answer important fundamental questions in biology. Warwick Integrative Synthetic Biology (WISB) pursues both of these mutually complementary 'build to apply' and 'build to understand' approaches. This is reflected in our research structure, in which a core theme on predictive biosystems engineering develops underpinning understanding as well as next-generation experimental/theoretical tools, and these are then incorporated into three applied themes in which we engineer biosynthetic pathways, microbial communities and microbial effector systems in plants. WISB takes a comprehensive approach to training, education and outreach. For example, WISB is a partner in the EPSRC/BBSRC-funded U.K. Doctoral Training Centre in synthetic biology, we have developed a new undergraduate module in the subject, and we have established five WISB Research Career Development Fellowships to support young group leaders. Research in Ethical, Legal and Societal Aspects (ELSA) of synthetic biology is embedded in our centre activities. WISB has been highly proactive in building an international research and training network that includes partners in Barcelona, Boston, Copenhagen, Madrid, Marburg, São Paulo, Tartu and Valencia. PMID:27284024

  3. Vertical distribution of sediment concentration

    Institute of Scientific and Technical Information of China (English)

    Sai-hua HUANG; Zhi-lin SUN; Dan XU; Shan-shan XIA

    2008-01-01

    A simple formula is proposed to predict the vertical distribution of a suspended load concentration in a 2D steady turbulent flow.The proposed formula significantly improves the well-known Rouse formula where sediment concentration has an infinitely large value at the channel bottom and a zero value at the water surface.Based on this formula and the logarithmic ve-locity profile,a theoretical elementary function for the transport rate of a suspended load is developed.This equation improves the Einstein equation in which the unit-width suspended sediment discharge must be solved by numerical integration and a contra-diction between the lower limit of the integral and that of velocity distribution exists.

  4. Transmission line capital costs

    International Nuclear Information System (INIS)

    The displacement or deferral of conventional AC transmission line installation is a key benefit associated with several technologies being developed with the support of the U.S. Department of Energy's Office of Energy Management (OEM). Previous benefits assessments conducted within OEM have been based on significantly different assumptions for the average cost per mile of AC transmission line. In response to this uncertainty, an investigation of transmission line capital cost data was initiated. The objective of this study was to develop a database for preparing preliminary estimates of transmission line costs. An extensive search of potential data sources identified databases maintained by the Bonneville Power Administration (BPA) and the Western Area Power Administration (WAPA) as superior sources of transmission line cost data. The BPA and WAPA data were adjusted to a common basis and combined together. The composite database covers voltage levels from 13.8 to 765 W, with cost estimates for a given voltage level varying depending on conductor size, tower material type, tower frame type, and number of circuits. Reported transmission line costs vary significantly, even for a given voltage level. This can usually be explained by variation in the design factors noted above and variation in environmental and land (right-of-way) costs, which are extremely site-specific. Cost estimates prepared from the composite database were compared to cost data collected by the Federal Energy Regulatory Commission (FERC) for investor-owned utilities from across the United States. The comparison was hampered because the only design specifications included with the FERC data were voltage level and line length. Working within this limitation, the FERC data were not found to differ significantly from the composite database. Therefore, the composite database was judged to be a reasonable proxy for estimating national average costs

  5. Modeling effective transmission pathways and control of the world's most successful parasite.

    Science.gov (United States)

    Turner, Matthew; Lenhart, Suzanne; Rosenthal, Benjamin; Zhao, Xiaopeng

    2013-06-01

    Toxoplasma gondii(T. gondii) is a single-celled, intracellular protozoan responsible for the disease toxoplasmosis. The parasite is prevalent worldwide, and it infects all warm-blooded vertebrates. Consumption of meats in which this parasite has encysted confers risk of infection to people and other animals, as does ingestion of water or foods contaminated with environmentally resistant oocysts excreted by cats. Vertical transmission (from mother to offspring) is also possible, leading to disease risk and contributing additional means of ensuring perpetuation of transmission. In this work, we adopt a differential equation model to investigate the effective transmission pathways of T. gondii, as well as potential control mechanisms. Detailed analyses are carried out to examine the significance of transmission routes, virulence, vertical transmission, parasite-induced changes in host behavior, and controls based on vaccination and harvesting. Modeling and analysis efforts may shed insights into understanding the complex life cycle of T. gondii. PMID:23624067

  6. Transmission grid security

    CERN Document Server

    Haarla, Liisa; Hirvonen, Ritva; Labeau, Pierre-Etienne

    2011-01-01

    In response to the growing importance of power system security and reliability, ""Transmission Grid Security"" proposes a systematic and probabilistic approach for transmission grid security analysis. The analysis presented uses probabilistic safety assessment (PSA) and takes into account the power system dynamics after severe faults. In the method shown in this book the power system states (stable, not stable, system breakdown, etc.) are connected with the substation reliability model. In this way it is possible to: estimate the system-wide consequences of grid faults; identify a chain of eve

  7. Viewing transmission issues in perspective

    International Nuclear Information System (INIS)

    This article examines electric power transmission from the perspective of the power producers. The article discusses the impact to transmission line routing policy of the health effects of, and public opinion about, electromagnetic fields. The author examines past pricing policy for transmission access and encourages the power producers and owners of transmission lines to become more involved in the regulatory process

  8. Viewing transmission issues in perspective

    Energy Technology Data Exchange (ETDEWEB)

    Casazza, J.A.

    1993-10-01

    This article examines electric power transmission from the perspective of the power producers. The article discusses the impact to transmission line routing policy of the health effects of, and public opinion about, electromagnetic fields. The author examines past pricing policy for transmission access and encourages the power producers and owners of transmission lines to become more involved in the regulatory process.

  9. Economical quantum anonymous transmissions

    International Nuclear Information System (INIS)

    We present a new information-theoretically secure protocol for the anonymous transmission of quantum information. Different from the pioneering works, we use single photons to construct anonymous entanglement instead of multi-partite entangled states in this protocol, and therefore we reduce the complexity of physical implementation in practice.

  10. Watching Handball Transmissions

    DEFF Research Database (Denmark)

    Frandsen, Kirsten

    2010-01-01

    competent when mastering the game and in relation to others. The study shows that entertainment concerns both affective involvement and identity formation, as social and cultural meaning seem to be at the root of involvement. Even though both men and women find great joy in the transmissions, their viewing...

  11. Improving Transmission Planning

    OpenAIRE

    Saraswat, Kavita; Gupta, Amol

    2016-01-01

    Development of power transmission networks requires long lead times and substantial capital. Optimization of investment is especially critical in fast-growing economies such as India’s, where there are competing demands on financial resources, and utilities need to maintain adequate cash flow to expand electricity service for economic growth and poverty reduction. As shown by examples from...

  12. Dilemmas of Cultural Transmission

    Science.gov (United States)

    Kováts-Németh, Mária

    2016-01-01

    The fundamental problem of the 21st century is that in the modern civilization "the transmission of values is not stable." There is nothing, except for the natural sense of justice and some legal traditions, which would exercise selective power on social behavior. At a critical time in 1949 Albert Szent-Györgyi drew the attention to the…

  13. Strategic investment in merchant transmission: The impact of capacity utilization rules

    International Nuclear Information System (INIS)

    In this paper we look at the relative merits of two capacity utilization regimes in the merchant electricity transmission network: Must offer (Mo) where the entire capacity installed has to be made available for transmission and Non Must Offer (NMo) where some capacity could be withheld. We look at two specific cases: (i) demand for transmission varies across time, and (ii) vertical integration is allowed between investors in transmission network and electricity generators. In the case of time-varying demand under Mo, we find that a monopolist may underinvest in transmission when compared to NMo, although NMo may lead to more capacity withholding. In the case of vertical integration, we find that when the market power is with the generators of the exporting node, without vertical integration no welfare-enhancing merchant investment would occur, neither under Mo nor NMo. Further, if the generators in the importing node have market power, in case vertical integration is allowed, Mo is better than NMo. Finally, we also argue that the incentive to collude among various transmission network investors is mitigated with Mo in place. -- Highlights: •We model merits of Must offer (Mo) versus non-Must offer (NMo) regimes. •With fluctuating demand, NMo in general may generate more investment in capacity. •At the same time it may reduce capacity utilization. •With market power in the inefficient generating node, Mo is welfare-enhancing. •Collusion is mitigated with 'must offer' regime in place

  14. The effect of centre of mass location on sagittal plane moments around the centre of mass in trotting horses.

    Science.gov (United States)

    Hobbs, Sarah Jane; Richards, Jim; Clayton, Hilary M

    2014-04-11

    The diagonal limb support pattern at trot provides pitch and roll stability, but little is known about the control of moments about the centre of mass (COM) in horses. Correct COM location is critical in the calculation of pitching moments. The objectives were to determine the effect of COM location on pitching moments in trotting horses and explore how COM location could influence balance. Kinematic (120 Hz) and GRF (4 force plates, 960 Hz) data were collected at trot from three trials of eight horses. The position of the COM was determined from the weighted summation of the segmental COMs and this was then manipulated cranially and caudally to test the model. Sagittal-plane moments around the COM were calculated for each manipulation of the model and their relationship determined using reduced major axis regression. Over the stride, the moments must sum to zero to prevent accumulation of rotational motion. This was found when the weight on the forelimbs in standing was 58.7% ± 3% (mean ± 95% C.I.), which corresponded closely to the COP ratio in standing. Moments were typically nose-up at foot strike changing to nose-down prior to midstance, and then reversing to nose-up in late stance. Mean moments were larger in the hindlimbs and more sensitive to COM location changes. Divergence of the COM from the COP creating a vertical force moment arm prior to midstance may assist the hindlimb in relation to propulsive effort. A similar effect is seen in the forelimb during single limb support. PMID:24636530

  15. On Vertical Relations and Technology Adoption Timing

    OpenAIRE

    Maria Alipranti; Chrysovalantou Miliou; Emmanuel Petrakis

    2014-01-01

    This paper explores how vertical relations influence the timing of new technology adoption. It shows that both the bargaining power distribution among the vertically related firms and the contract type through which vertical trading is conducted affect crucially the speed of adoption: the downstream firms can adopt later a new technology when the upstream bargaining power increases as well as when wholesale price contracts, instead of two-part tariffs, are employed. Importantly, it shows that...

  16. The green building envelope: vertical greening

    OpenAIRE

    Ottelé, M.

    2011-01-01

    Planting on roofs and façades is one of the most innovative and fastest developing fields of green technologies with respect to the built environment and horticulture. This thesis is focused on vertical greening of structures and to the multi-scale benefits of vegetation. Vertical green can improve the environment in urban areas and is becoming a key design consideration in modern building developments. Vertical greening of structures offers large surfaces with vegetation and at the same time...

  17. How vertically specialized is Chinese trade?

    OpenAIRE

    Dean, Judith; Fung, K. C.; Wang, Zhi

    2008-01-01

    Two recent phenomena have transformed the nature of world trade: the explosive growth of Chinese trade, and the growth of vertically specialized trade due to international production fragmentation. While vertical specialization may explain much of the growth and unique features of Chinese trade, few papers have quantitatively assessed these two phenomena together. In part, this is because it is difficult to measure just how vertically specialized Chinese trade is. The unique features of China...

  18. Surface tension profiles in vertical soap films

    OpenAIRE

    Adami, N.; Caps, H.

    2013-01-01

    Surface tension profiles in vertical soap films are experimentally investigated. Measurements are performed introducing deformable elastic objets in the films. The shape adopted by those objects set in the film can be related to the surface tension value at a given vertical position by numerical solving of adapted elasticity equations. We show that the observed dependency of the surface tension versus the vertical position in the soap film can be reproduced by simple modeling taking into acco...

  19. Plasmonic Properties of Vertically Aligned Nanowire Arrays

    OpenAIRE

    Hua Qi; Glembocki, O. J.; Prokes, S. M.

    2012-01-01

    Nanowires (NWs)/Ag sheath composites were produced to investigate plasmonic coupling between vertically aligned NWs for surface-enhanced Raman scattering (SERS) applications. In this investigation, two types of vertical NW arrays were studied; those of ZnO NWs grown on nanosphere lithography patterned sapphire substrate via vapor-liquid-solid (VLS) mechanism and Si NW arrays produced by wet chemical etching. Both types of vertical NW arrays were coated with a thin layer of silver by electrole...

  20. Turbulence in vertical axis wind turbine canopies

    OpenAIRE

    Kinzel, Matthias; Araya, Daniel B.; Dabiri, John O.

    2015-01-01

    Experimental results from three different full scale arrays of vertical-axis wind turbines (VAWTs) under natural wind conditions are presented. The wind velocities throughout the turbine arrays are measured using a portable meteorological tower with seven, vertically staggered, three-component ultrasonic anemometers. The power output of each turbine is recorded simultaneously. The comparison between the horizontal and vertical energy transport for the different turbine array sizes shows the i...