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Sample records for centre london uk

  1. Institutional profile: the London Centre for Nanotechnology.

    Science.gov (United States)

    Weston, David; Bontoux, Thierry

    2009-12-01

    Located in the London neighborhoods of Bloomsbury and South Kensington, the London Centre for Nanotechnology is a UK-based multidisciplinary research center that operates at the forefront of science and technology. It is a joint venture between two of the world's leading institutions, UCL and Imperial College London, uniting their strong capabilities in the disciplines that underpin nanotechnology: engineering, the physical sciences and biomedicine. The London Centre for Nanotechnology has a unique operating model that accesses and focuses the combined skills of the Departments of Chemistry, Physics, Materials, Medicine, Electrical and Electronic Engineering, Mechanical Engineering, Chemical Engineering, Biochemical Engineering and Earth Sciences across the two universities. It aims to provide the nanoscience and nanotechnology required to solve major problems in healthcare, information processing, energy and the environment.

  2. The introduction of 10% renewable energy in every building. Possibility or probability? Case study: Granville plus community Centre London, UK

    Science.gov (United States)

    Tsitnidis, Petros

    This thesis investigates the ways of producing 10% of the energy consumed in a site from renewable energy sources. It analyses how this can be accomplished by considering the general frame of the subject and referring to the general problem of climate change and its effects on the planet. Special attention is paid to architecture and an attempt is made to answer the question how the built environment can cope with this problem. Reference is also made to the UK's latest guidelines on the issue. The introduction of the 10% renewable energy use in buildings, known as the "Merton Rule", is one of the most pioneering guidelines towards sustainability. The thesis is continued with the post-occupancy assessment on a four year-old building, part of a much older community center complex that has been built with very advanced design and strict environmental targets but suffers from lack of care and management. The building does not achieve optimum performance as there are difficulties with various stakeholders in the buildings management. This thesis, therefore, examines possible solutions and suggests ways of improvement. The study concludes with remarks and suggestions based on simulation and assessment procedures. New ventilation strategies are proposed to be introduced to the building together with a series of ways to reduce the highest internal temperatures of the first floor. Extensive reference is also made to the initial sustainable approach of the design. The interventions proposed have as a target the improvement of the energy performance and the minimization of the carbon footprint of the building. Keywords: environmental design, sustainable architecture, granville plus, Merton Rule.

  3. Carbon dioxide and methane emission dynamics in central London (UK)

    Science.gov (United States)

    Helfter, Carole; Nemitz, Eiko; Barlow, Janet F.; Wood, Curtis R.

    2013-04-01

    London, with a population of 8.2 million, is the largest city in Europe. It is heavily built-up (typically 8% vegetation cover within the central boroughs) and boasts some of the busiest arteries in Europe despite efforts to reduce traffic in the city centre with the introduction of a congestion charging scheme in 2007. We report on two substantial pollution monitoring efforts in the heart of London between October 2006 and present. Fluxes of carbon dioxide (CO2) and water (H2O) were measured continuously by eddy-covariance in central London from October 2006 until May 2008 from a 190 m telecommunication tower (BT tower; 51° 31' 17.4'' N 0° 8' 20.04'' W). The eddy-covariance system consisted of a Gill R3-50 ultrasonic anemometer operated at 20 Hz and a LI-COR 6262 infrared gas analyser. Air was sampled 0.3 m below the sensor head of the ultrasonic anemometer - which was itself mounted on a 3 m mast to the top of a 15 m lattice tower situated on the roof of the tower (instrument head at 190 m above street level) - and pulled down 45 m of 12.7 mm OD Teflon tubing. In addition, meteorological variables (temperature, relative humidity, pressure, precipitation, wind speed and direction) were also measured with a multi-sensor (Weather Transmitter WXT510, Vaisala). Eddy-covariance measurements at the BT tower location were reinstated in July 2011 and include methane (CH4), CO2 and H2O concentrations measured by a Picarro fast methane analyser (G2301-f). CO2 emissions were found to be mainly controlled by fossil fuel combustion (e.g. traffic, commercial and domestic heating). Diurnal averages of CO2 fluxes were found to be highly correlated to traffic. However changes in heating-related natural gas consumption and, to a lesser extent, photosynthetic activity in two large city centre green spaces (Hyde Park and Regent's Park) explained the seasonal variability. Annual estimates of net exchange of CO2 obtained by eddy-covariance agreed well with up-scaled data from the UK

  4. Improved Survival from Ovarian Cancer in Patients Treated in Phase III Trial Active Cancer Centres in the UK.

    Science.gov (United States)

    Khoja, L; Nolan, K; Mekki, R; Milani, A; Mescallado, N; Ashcroft, L; Hasan, J; Edmondson, R; Winter-Roach, B; Kitchener, H C; Mould, T; Hutson, R; Hall, G; Clamp, A R; Perren, T; Ledermann, J; Jayson, G C

    2016-12-01

    Ovarian cancer is the principal cause of gynaecological cancer death in developed countries, yet overall survival in the UK has been reported as being inferior to that in some Western countries. As there is a range of survival across the UK we hypothesised that in major regional centres, outcomes are equivalent to the best internationally. Data from patients treated in multicentre international and UK-based trials were obtained from three regional cancer centres in the UK; Manchester, University College London and Leeds (MUL). The median progression-free survival (PFS) and overall survival were calculated for each trial and compared with the published trial data. Normalised median survival values and the respective 95% confidence intervals (ratio of pooled MUL data to trial median survival) were calculated to allow inter-trial survival comparisons. This strategy then allowed a comparison of median survival across the UK, in three regional UK centres and in international centres. The analysis showed that the trial-reported PFS was the same in the UK, in the MUL centres and in international centres for each of the trials included in the study. Overall survival was, however, 45% better in major regional centre-treated patients (95% confidence interval 9-73%) than the median overall survival reported in UK trials, whereas the median overall survival in MUL centres equated with that achieved in international centres. The data suggest that international survival statistics are achieved in UK regional cancer centres. Copyright © 2016 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

  5. London Calling Olympic spotlight will shine on U.K. consumer

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Come summer, the international spotlight will shine on the United Kingdom when the 2012 Olympics begin in London. While billions worldwide wilt be watching athletes striving to achieve their personal best, the coverage will also allow viewers to learn about the U.K. and its denizens. For apparel brands and retailers, it could offer a glimpse into possible new selling opportunities.

  6. Lively Bureaucracy? The ESRC's Doctoral Training Centres and UK Universities

    Science.gov (United States)

    Lunt, Ingrid; McAlpine, Lynn; Mills, David

    2014-01-01

    This paper explores the changing relationships between the UK government, its research councils and universities, focusing on the governing, funding and organisation of doctoral training. We use the Doctoral Training Centres (DTCs) funded by the Economic and Social Research Council (ESRC) as a prism through which to study the shifting nature of…

  7. Evaluating the use of an urban consolidation centre and electric vehicles in central London

    Directory of Open Access Journals (Sweden)

    Michael Browne

    2011-07-01

    Full Text Available The paper focuses on the role that can be played by urban consolidation centres (UCCs in reducing freight traffic and its environmental impacts in towns and cities. It is based on the before and after evaluation of a trial led by a major stationery and office supplies company in which urban freight deliveries in central London made from a depot in the suburbs using diesel vehicles were replaced with the use of an urban micro-consolidation centre located in the delivery area together with the use of electrically-assisted cargo tricycles and electric vans. The results show that the total distance travelled and the CO2eq emissions per parcel delivered fell by 20% and 54% respectively as a result of this delivery system. However, the evaluation has also indicated that the distance travelled per parcel rose substantially in the City of London delivery area as a result of the electric vehicles having far smaller load limits in both weight and volume compared with diesel vans. But, at the same time, the trial system was able to virtually eliminate CO2eq emissions per parcel delivered in the City of London. The trial proved successful from the company's perspective in transport, environmental and financial terms. The company therefore decided to continue the operation beyond the end of the trial with it being officially launched during 2010.

  8. Application of MM5/CMAQ for modelling urban air pollution a case study for London, UK

    Science.gov (United States)

    Kitwiroon, N.; Fragkou, E.; Sokhi, R. S.; San Jose, R.; Pérez Camaño, J. L.; Middleton, D.

    2003-04-01

    Urban air pollution has been particularly studied for the last few decades because of its recognised environmental dangers and health implications. The complexity of the urban surface characteristics and turbulence patterns has dictated the use of numerical models by environmental research agencies and regulators in order to predict and manage urban air pollution. However, most of these models are not specifically adapted to urban applications and normally do not include detailed urban parameterisation, such as for surface roughness or urban heat fluxes. Flow structure and dispersion of air pollutants within cities, however, are influenced by urban features such as increased surface roughness. This paper presents a study using MM5 and CMAQ to assess the effect of urban boundary layer features on meteorological parameters, and hence London's air quality. MM5 is a non-hydrostatic (version 3), terrain-following sigma-coordinate model designed to simulate mesoscale and regional-scale atmospheric circulation. This paper employs an improved surface roughness treatment on meteorological profiles and pollution dispersion. A surface roughness scale has been developed for London and the surrounding region. The land cover data was derived from the Centre for Ecology and Hydrology (CEH) data, with a spatial resolution of 25 × 25 m. These z_o values are employed with MM5 for modelling meteorological parameters over London, covering an inner domain area of 49 × 49 km. The outputs of MM5 have been coupled to CMAQ photochemical model to predict concentrations of particles, NO_2 and O_3 for London and the surrounding regions at a spatial resolution of 1 × 1 km. The predicted concentrations have been compared with monitored data obtained from a range of national air quality monitoring sites including Central London (Bloomsbury, Brent), East London (Bexley) and West London (Hillingdon). Comparison of hourly model predictions with measured data is made for pollution levels for

  9. Bullying, "Cussing" and "Mucking About": Complexities in Tackling Homophobia in Three Secondary Schools in South London, UK

    Science.gov (United States)

    Warwick, Ian; Aggleton, Peter

    2014-01-01

    In countries such as the UK, schools have a responsibility to prevent all forms of bullying, including those related to sexual orientation. However, relatively little is known about how schools go about this work successfully. This study aimed to identify how three secondary schools in south London, England, were addressing homophobia. Three…

  10. Prevalence, determinants and clinical correlates of vitamin D deficiency in adults with inhaled corticosteroid-treated asthma in London, UK.

    Science.gov (United States)

    Jolliffe, David A; Kilpin, Kate; MacLaughlin, Beverley D; Greiller, Claire L; Hooper, Richard L; Barnes, Neil C; Timms, Peter M; Rajakulasingam, Raj K; Bhowmik, Angshu; Choudhury, Aklak B; Simcock, David E; Hyppönen, Elina; Corrigan, Christopher J; Walton, Robert T; Griffiths, Christopher J; Martineau, Adrian R

    2016-11-05

    Vitamin D deficiency is common in children with asthma, and it associates with poor asthma control, reduced forced expiratory volume in one second (FEV1) and increased requirement for inhaled corticosteroids (ICS). Cross-sectional studies investigating the prevalence, determinants and clinical correlates of vitamin D deficiency in adults with asthma are lacking. We conducted a multi-centre cross-sectional study in 297 adults with a medical record diagnosis of ICS-treated asthma living in London, UK. Details of potential environmental determinants of vitamin D status, asthma control and medication use were collected by questionnaire; blood samples were taken for analysis of serum 25(OH)D concentration and DNA extraction, and participants underwent measurement of weight, height and fractional exhaled nitric oxide concentration (FeNO), spirometry and sputum induction for determination of lower airway eosinophil counts (n=35 sub-group). Thirty-five single nucleotide polymorphisms (SNP) in 11 vitamin D pathway genes (DBP, DHCR7, RXRA, CYP2R1, CYP27B1, CYP24A1, CYP3A4 CYP27A1, LRP2, CUBN, VDR) were typed using Taqman allelic discrimination assays. Linear regression was used to identify environmental and genetic factors independently associated with serum 25(OH)D concentration, and to determine whether vitamin D status was independently associated with Asthma Control Test (ACT) score, ICS dose, FeNO, forced vital capacity (FVC), FEV1 or lower airway eosinophilia. Mean serum 25(OH)D concentration was 50.6nmol/L (SD 24.9); 162/297 (54.5%) participants were vitamin D deficient (serum 25(OH)D concentration D status was associated with higher body mass index (P=0.014), non-White ethnicity (P=0.036), unemployment (P for trend=0.012), lack of vitamin D supplement use (PD status was not found to associate with any marker of asthma control investigated. Vitamin D deficiency is common among UK adults with ICS-treated asthma, and classical environmental determinants of serum 25(OH

  11. Centre of IT Excellence for SMEs in the West Midlands, UK: A Suitable Project Methodology

    Science.gov (United States)

    Thompson, Diana; Homer, Garry

    2005-01-01

    This paper presents an analysis of the IT Futures Centre, a European technology transfer project based at the University of Wolverhampton in the UK. After reviewing UK government policy in technology transfer, the authors highlight the project's two key elements--a new state-of-the-art building and an IT consultancy team--both of which are…

  12. Sources of greenhouse gases and carbon monoxide in central London (UK)

    Science.gov (United States)

    Helfter, Carole; Tremper, Anja; Zazzeri, Giulia; Barlow, Janet F.; Nemitz, Eiko

    2015-04-01

    Biosphere-atmosphere exchange of carbon dioxide (CO2) has been on the scientific agenda for several decades and new technology now also allows for high-precision, continuous monitoring of fluxes of methane (CH4) and nitrous oxide (N2O). Compared to the natural environment, flux measurements in the urban environment, which is home to over 50% of the population globally, are still rare despite high densities of anthropogenic sources of pollutants. We report on over three years of measurements atop a 192 m tower in central London (UK), Europe's largest city, which started in October 2011. Fluxes of methane, carbon monoxide (CO) and carbon dioxide are measured by eddy-covariance (EC) at the British Telecom tower (51° 31' 17.4' N 0° 8' 20.04' W). In addition to the long-term measurements, EC fluxes of nitrous oxide (N2O) were measured in February 2014. All four trace gases exhibit diurnal trends consistent with anthropogenic activities with minimum emissions at night and early afternoon maxima. Segregating emissions by wind direction reveals heterogeneous source distributions with temporal patterns and source strengths that differ between compounds. The lowest emissions for CO, CO2 and CH4 were recorded for NW winds. The highest emissions of methane were in the SE sector, in the NE for CO2 and in the W for CO. Fluxes of all 3 gases exhibited marked seasonal trends characterised by a decrease in emissions in summer (63% reduction for CO, 36% for CO2 and 22% for CH4). Monthly fluxes of CO and CO2 were linearly correlated to air temperature (R2 = 0.7 and 0.59 respectively); a weaker dependence upon temperature was also observed for CH4 (R2 = 0.31). Diurnal and seasonal emissions of CO and CO2 are mainly controlled by local fossil fuel combustion and vehicle cold starts are thought to account for 20-30% of additional emissions of CO during the winter. Fugitive emissions of CH4 from the natural gas distribution network are thought to be substantial, which is consistent

  13. Factors Affecting the Involvement of Day Centre Care Staff in the Delivery of Physiotherapy to Adults with Intellectual Disabilities: An Exploratory Study in One London Borough

    Science.gov (United States)

    Middleton, M. -J.; Kitchen, S. S.

    2008-01-01

    Background: Physiotherapists for adults with intellectual disabilities often work in day centres, relying on care staff to support programmes. This study investigates factors affecting physiotherapy delivery in 4 day centres in one London borough. Materials and Method: Semi-structured interviews were carried out with day centre care staff,…

  14. Pedestrian exposure to air pollution along a major road in Central London, UK

    Science.gov (United States)

    Kaur, S.; Nieuwenhuijsen, M. J.; Colvile, R. N.

    Pedestrian exposure to PM 2.5, the loss of reflectance ('blackness') of the PM 2.5 filters, ultrafine particle counts (particle range: 0.02-1 μm) and carbon monoxide (CO) was investigated along a major road running through the DAPPLE study site in Central London, UK. During an intensive 12-day exposure measurement campaign, groups of four volunteers sampled twice in the morning and twice in the afternoon along Marylebone Road. They were randomly designated a walking direction, walking position (kerbside or buildingside) and a side of the major road to walk along. PM 2.5 was sampled using high-flow gravimetric personal samplers, ultrafine particle counts were measured using TSI P-TRAKs and Langans were used to measure CO exposure. PM 2.5 samples were analysed gravimetrically and reflectance was measured using a smoke stain reflectometer to obtain a measure of 'black smoke'. In total 603 acceptable samples were obtained—155 PM 2.5 and reflectance, 120 ultrafine particle count and 173 CO. The average pedestrian exposure along the road was 37.7 μg/m 3, 12.1 m -1×10 -5, 80 009 pt/cm 3 and 1.3 ppm for PM 2.5, loss of reflectance, ultrafine particle counts and CO, respectively. PM 2.5 exposure in the morning was significantly higher than in the afternoon, and there was a significant difference in exposure on the different sides of the road. For both reflectance and ultrafine particle counts, the exposure was significantly different both between the two walking positions on the pavement and the two sides of the street canyon. However there was no significant difference in CO exposure based on walking position, walking direction, canyon side or timing. Filter reflectance was significantly but weakly correlated with PM 2.5 exposure ( r=0.3, N=155), CO exposure ( r=0.2, N=154) and ultrafine particle count exposure ( r=0.7, N=108). PM 2.5 and CO personal exposure measurements were much higher than those recorded at both the local background fixed monitoring station (FMS

  15. Receptor modelling of both particle composition and size distribution from a background site in London, UK

    Science.gov (United States)

    Beddows, D. C. S.; Harrison, R. M.; Green, D. C.; Fuller, G. W.

    2015-09-01

    Positive matrix factorisation (PMF) analysis was applied to PM10 chemical composition and particle number size distribution (NSD) data measured at an urban background site (North Kensington) in London, UK, for the whole of 2011 and 2012. The PMF analyses for these 2 years revealed six and four factors respectively which described seven sources or aerosol types. These included nucleation, traffic, urban background, secondary, fuel oil, marine and non-exhaust/crustal sources. Urban background, secondary and traffic sources were identified by both the chemical composition and particle NSD analysis, but a nucleation source was identified only from the particle NSD data set. Analysis of the PM10 chemical composition data set revealed fuel oil, marine, non-exhaust traffic/crustal sources which were not identified from the NSD data. The two methods appear to be complementary, as the analysis of the PM10 chemical composition data is able to distinguish components contributing largely to particle mass, whereas the number particle size distribution data set - although limited to detecting sources of particles below the diameter upper limit of the SMPS (604 nm) - is more effective for identifying components making an appreciable contribution to particle number. Analysis was also conducted on the combined chemical composition and NSD data set, revealing five factors representing urban background, nucleation, secondary, aged marine and traffic sources. However, the combined analysis appears not to offer any additional power to discriminate sources above that of the aggregate of the two separate PMF analyses. Day-of-the-week and month-of-the-year associations of the factors proved consistent with their assignment to source categories, and bivariate polar plots which examined the wind directional and wind speed association of the different factors also proved highly consistent with their inferred sources. Source attribution according to the air mass back trajectory showed, as

  16. Effects of the urban heat island on the phenology of Odonata in London, UK

    Science.gov (United States)

    Villalobos-Jiménez, Giovanna; Hassall, Christopher

    2017-02-01

    Urbanisation is one of the major drivers of ecosystem change and includes increased temperatures in cities leading to an urban heat island (UHI). This study quantified the phenological response of odonates across London, UK, from 1990 to 2012, using a database of 1,031,277 historical sightings. The ordinal flight dates of each species were used to calculate the leading edge, middle and trailing edge of the flight period (P5, P50 and P95, respectively). The results suggest that the phenology of odonates is affected by the UHI only at a community level: no significant changes in the P5 or P50 of the flight period were found, although the P95 shows a mean advance of 4.13 days compared to rural areas, thus suggesting a contraction of the flight period in urban areas. However, only one individual species (Sympetrum striolatum) exhibited an advance in the P95 of the flight period in urban areas compared to rural areas. On the other hand, climate change (minimum temperature) had a much stronger impact on the phenology of odonates at the community level with a significant advance of 6.9 days °C-1 in the P5 of the flight period, 3.1 days °C-1 in the P50 and 3.3 days °C-1 in the P95 flight date. Similarly, a significant advance in P5 was found in 7 of the 15 species tested in response to minimum temperature, and 2 species showed a significant advance in P50 in response to minimum temperature, but no species showed a shift in the P95 flight date due to minimum temperature. As shown in previous studies, life history influences the phenological response of odonates, with spring species and those species lacking an egg diapause being the most responsive to increased temperatures, although summer species and species with obligate egg diapause also respond to the UHI by advancing the P95 by 3.8 and 4.5 days, respectively, compared to rural areas, thus contracting the flight period. The present study shows that the UHI has negligible impacts on emergence patterns of odonates

  17. Regional methods for mapping major faults in areas of uniform low relief, as used in the London Basin, UK

    Science.gov (United States)

    Haslam, Richard; Aldiss, Donald

    2013-04-01

    Most of the London Basin, south-eastern UK, is underlain by the Palaeogene London Clay Formation, comprising a succession of rather uniform marine clay deposits up to 150 m thick, with widespread cover of Quaternary deposits and urban development. Therefore, in this area faults are difficult to delineate (or to detect) by conventional geological surveying methods in the field, and few are shown on the geological maps of the area. However, boreholes and excavations, especially those for civil engineering works, indicate that faults are probably widespread and numerous in the London area. A representative map of fault distribution and patterns of displacement is a pre-requisite for understanding the tectonic development of a region. Moreover, faulting is an important influence on the design and execution of civil engineering works, and on the hydrogeological characteristics of the ground. This paper reviews methods currently being used to map faults in the London Basin area. These are: the interpretation of persistent scatterer interferometry (PSI) data from time-series satellite-borne radar measurements; the interpretation of regional geophysical fields (Bouguer gravity anomaly and aeromagnetic), especially in combination with a digital elevation model; and the construction and interpretation of 3D geological models. Although these methods are generally not as accurate as large-scale geological field surveys, due to the availability of appropriate data in the London Basin they provide the means to recognise and delineate more faults, and with more confidence, than was possible using traditional geological mapping techniques. Together they reveal regional structures arising during Palaeogene crustal extension and subsidence in the North Sea, followed by inversion of a Mesozoic sedimentary basin in the south of the region, probably modified by strike-slip fault motion associated with the relative northward movement of the African Plate and the Alpine orogeny. This

  18. Prevalence, determinants and clinical correlates of vitamin D deficiency in patients with Chronic Obstructive Pulmonary Disease in London, UK.

    Science.gov (United States)

    Jolliffe, David A; James, Wai Yee; Hooper, Richard L; Barnes, Neil C; Greiller, Claire L; Islam, Kamrul; Bhowmik, Angshu; Timms, Peter M; Rajakulasingam, Raj K; Choudhury, Aklak B; Simcock, David E; Hyppönen, Elina; Walton, Robert T; Corrigan, Christopher J; Griffiths, Christopher J; Martineau, Adrian R

    2017-02-01

    Vitamin D deficiency is common in patients with chronic obstructive pulmonary disease (COPD), yet a comprehensive analysis of environmental and genetic determinants of serum 25-hydroxyvitamin D (25[OH]D) concentration in patients with this condition is lacking. We conducted a multi-centre cross-sectional study in 278 COPD patients aged 41-92 years in London, UK. Details of potential environmental determinants of vitamin D status and COPD symptom control and severity were collected by questionnaire, and blood samples were taken for analysis of serum 25(OH)D concentration and DNA extraction. All participants performed spirometry and underwent measurement of weight and height. Quadriceps muscle strength (QS) was measured in 134 participants, and sputum induction with enumeration of lower airway eosinophil and neutrophil counts was performed for 44 participants. Thirty-seven single nucleotide polymorphisms (SNP) in 11 genes in the vitamin D pathway (DBP, DHCR7, CYP2R1, CYP27B1, CYP24A1, CYP27A1, CYP3A4, LRP2, CUBN, RXRA, and VDR) were typed using Taqman allelic discrimination assays. Linear regression was used to identify environmental and genetic factors independently associated with serum 25(OH)D concentration and to determine whether vitamin D status or genetic factors independently associated with % predicted forced expiratory volume in one second (FEV1), % predicted forced vital capacity (FVC), the ratio of FEV1 to FVC (FEV1:FVC), daily inhaled corticosteroid (ICS) dose, respiratory quality of life (QoL), QS, and the percentage of eosinophils and neutrophils in induced sputum. Mean serum 25(OH)D concentration was 45.4nmol/L (SD 25.3); 171/278 (61.5%) participants were vitamin D deficient (serum 25[OH]D concentration D status was independently associated with higher body mass index (P=0.001), lower socio-economic position (P=0.037), lack of vitamin D supplement consumption (PD deficiency associated with reduced % predicted FEV1 (P for trend=0.060) and % predicted

  19. Bilingual Behaviour, Attitudes, Identity and Vitality: Some Data from Japanese Speakers in London, UK

    Science.gov (United States)

    Brown, Ivan; Sachdev, Itesh

    2009-01-01

    Although the Japanese community in London is relatively small, its composition is stable and reflects several aspects of Japan's relationship with the international community. Yet there appears to have been no systematic research exploring patterns of bilingual behaviour in relation to social psychological processes amongst Japanese nationals in…

  20. Staff perceptions on patient motives for attending GP-led urgent care centres in London: a qualitative study.

    Science.gov (United States)

    Greenfield, Geva; Ignatowicz, Agnieszka; Gnani, Shamini; Bucktowonsing, Medhavi; Ladbrooke, Tim; Millington, Hugh; Car, Josip; Majeed, Azeem

    2016-01-14

    General practitioner (GP)-led urgent care centres were established to meet the growing demand for urgent care. Staff members working in such centres are central in influencing patients' choices about which services they use, but little is known about staff perceptions of patients' motives for attending urgent care. We hence aimed to explore their perceptions of patients' motives for attending such centres. A phenomenological, qualitative study, including semistructured interviews. The interviews were analysed using thematic content analysis. 2 GP-led urgent care centres in 2 academic hospitals in London. 15 staff members working at the centres including 8 GPs, 5 emergency nurse practitioners and 2 receptionists. We identified 4 main themes: 'Confusion about choices', 'As if increase of appetite had grown; By what it fed on', 'Overt reasons, covert motives' and 'A question of legitimacy'. The participants thought that the centres introduce convenient and fast access for patients. So convenient, that an increasing number of patients use them as a regular alternative to their community GP. The participants perceived that patients attend the centres because they are anxious about their symptoms and view them as serious, cannot get an appointment with their GP quickly and conveniently, are dissatisfied with the GP, or lack self-care skills. Staff members perceived some motives as legitimate (an acute health need and difficulties in getting an appointment), and others as less legitimate (convenience, minor illness, and seeking quicker access to hospital facilities). The participants perceived that patients attend urgent care centres because of the convenience of access relative to primary care, as well as sense of acuity and anxiety, lack self-care skills and other reasons. They perceived some motives as more legitimate than others. Attention to unmet needs in primary care can help in promoting balanced access to urgent care. Published by the BMJ Publishing Group Limited

  1. Biomarkers in Clinical Trials--SMi Conference. 23-24 September 2009, London, UK.

    Science.gov (United States)

    Walker, Glenda

    2009-11-01

    The Biomarkers in Clinical Trials conference, held in London, included topics covering new developments in the field of biomarkers. This conference report highlights selected presentations on the definition of biomarkers, the use of biomarkers to support decisions in drug development and to improve treatment outcomes, and the aims of the Biomarkers Consortium. A case study of the investigational drug selumetinib (AstraZeneca plc) is also discussed.

  2. Determinants of fine particle (PM{sub 2.5}) personal exposure levels in transport microenvironments, London, UK

    Energy Technology Data Exchange (ETDEWEB)

    Adams, H.S.; Nieuwenhuijsen, M.J.; Colville, R.N. [Imperial Coll. of Science, Technology and Medicine, TH Huxley School of Environment, Earth Sciences and Engineering, London (United Kingdom)

    2001-07-01

    A series of field studies were carried out in London, UK, during 1999-2000 in which over 400 fine particle (PM{sub 2.5}) personal exposure level measurements were taken for journeys in bicycle, bus, car and underground rail transport microenvironments. This was the first comprehensive PM{sub 2.5} personal exposure study of transport users. Both a fixed-route multi-transport mode study and a study of cyclists' commuter journeys were undertaken. Subsequent to these field studies regression modelling of possible influencing factors of these exposure levels was carried out. Meteorological variables, traffic density, mode and route were considered; the relationships of personal exposure levels with fixed site monitor (FSM) concentrations, and of the FSM concentrations with the potential predictor variables, were also investigated. This analysis of the determinants of transport user exposure to PM{sub 2.5} in London, UK, showed that wind speed had a significant influence on personal exposure levels, though explained only up to 20% of the variability of road transport user exposure levels. The occurrence of higher wind speeds was strongly associated with a decrease in personal exposure levels; a 1.5-2.0 fold difference in exposure level concentrations was estimated between the 10th and 90th percentiles of wind speed. Route was a significant factor, whilst mode was not a significant factor in the street microenvironment (between bicycle, bus and car modes); models incorporating route and mode, as well as wind speed, explained approximately 35% of the variability in PM{sub 2.5} exposure levels. Personal exposure levels were reasonably correlated with urban background FSM concentrations, for fixed-route road mode (bicycle, bus and car) exposure level concentrations, r=0.27 (p<0.01) and for commuter cyclists' exposure level concentrations r=0.58 (p<0.01). (Author)

  3. Open Innovation, Triple Helix and Regional Innovation Systems: Exploring CATAPULT Centres in the UK

    Science.gov (United States)

    Kerry, Christopher; Danson, Michael

    2016-01-01

    Through the lens of UK CATAPULT Centres this conceptual paper presents an examination of the links between open innovation, the Triple Helix model and regional innovation systems. Highlighting the importance of boundary-spanning intermediaries, the combined role of these concepts is explored in detail. A conceptual model is then proposed which…

  4. UK Renal Registry 17th Annual Report: Chapter 6 Adequacy of Haemodialysis in UK Adult Patients in 2013: National and Centre-specific Analyses.

    Science.gov (United States)

    Shaw, Catriona; Steenkamp, Retha; Davenport, Andrew

    2015-01-01

    Outcomes in patients treated with haemodialysis(HD) are potentially influenced by the delivered dose of dialysis. The UK Renal Association publishes clinical practice guidelines recommendations for dialysis dose. The urea reduction ratio (URR) is a widely used measure of dialysis dose and has been historically the measure of adequacy reported by the UKRR. To determine the extent to which patients achieved the recommended UK target. Two groups of patients were included in the analyses: the prevalent HD patients on 30th September 2013 and the incident HD patients for 2012. Centres returning data on ,50% of their patient population or centres with,20 patients with data were excluded from centre-specific comparisons. Data regarding URR were available for analysis from 64 renal centres in the UK. The proportion of patients in the UK who met the UK clinical practice guideline for URR (.65%) increased from 69% in 2000 to 89% in 2013. There was persistent variation observed between centres, with 22 centres attaining the RA clinical practice guideline in .90% of patients and 37 centres attaining the guideline in 70–90% of patients. The overall proportion of prevalent HD patients with a URR .65% has continued to improve over time. The delivered dose of HD,as measured by URR for patients with established renal failure,has increased over the last decade. Whilst the majority of UK patients achieved the target URR, there was wide variation between centres in the percentage of patients achieving the current guideline target.

  5. Spatial and temporal variability of urban fluxes of methane, carbon monoxide and carbon dioxide above London, UK

    Science.gov (United States)

    Helfter, Carole; Tremper, Anja H.; Halios, Christoforos H.; Kotthaus, Simone; Bjorkegren, Alex; Grimmond, C. Sue B.; Barlow, Janet F.; Nemitz, Eiko

    2016-08-01

    We report on more than 3 years of measurements of fluxes of methane (CH4), carbon monoxide (CO) and carbon dioxide (CO2) taken by eddy-covariance in central London, UK. Mean annual emissions of CO2 in the period 2012-2014 (39.1 ± 2.4 ktons km-2 yr-1) and CO (89 ± 16 tons km-2 yr-1) were consistent (within 1 and 5 % respectively) with values from the London Atmospheric Emissions Inventory, but measured CH4 emissions (72 ± 3 tons km-2 yr-1) were over two-fold larger than the inventory value. Seasonal variability was large for CO with a winter to summer reduction of 69 %, and monthly fluxes were strongly anti-correlated with mean air temperature. The winter increment in CO emissions was attributed mainly to vehicle cold starts and reduced fuel combustion efficiency. CO2 fluxes were 33 % higher in winter than in summer and anti-correlated with mean air temperature, albeit to a lesser extent than for CO. This was attributed to an increased demand for natural gas for heating during the winter. CH4 fluxes exhibited moderate seasonality (21 % larger in winter), and a spatially variable linear anti-correlation with air temperature. Differences in resident population within the flux footprint explained up to 90 % of the spatial variability of the annual CO2 fluxes and up to 99 % for CH4. Furthermore, we suggest that biogenic sources of CH4, such as wastewater, which is unaccounted for by the atmospheric emissions inventories, make a substantial contribution to the overall budget and that commuting dynamics in and out of central business districts could explain some of the spatial and temporal variability of CO2 and CH4 emissions. To our knowledge, this study is unique given the length of the data sets presented, especially for CO and CH4 fluxes. This study offers an independent assessment of "bottom-up" emissions inventories and demonstrates that the urban sources of CO and CO2 are well characterized in London. This is however not the case for CH4 emissions which are

  6. Complaints about dog faeces as a symbolic representation of incivility in London, UK: a qualitative study.

    Science.gov (United States)

    Derges, Jane; Lynch, Rebecca; Clow, Angela; Petticrew, Mark; Draper, Alizon

    2012-12-01

    During a 'Well London' study, residents were asked about their neighbourhood and its environment. Above all other complaints, 'dog poo' was mentioned as a key concern. Despite low rates of infection and disease among the human population resulting from contact with canine faecal matter, the concerns of the public continue to rate it as a serious public health issue. Most public health studies, therefore, seek to identify processes of transmission and disease pathology as a method of addressing the problem. This study approaches the issue through a contextualised analysis of residents' complaints, using anthropological theory to examine the symbolic representation of 'dog poo'. Analysis of the interviews shows that these specific complaints were located among less easily defined or articulated experiences of social and environmental neglect, where neighbours were estranged from one another and local authorities seen as negligent. This approach has important implications for public health, as it provides not only a strong indicator of the level of dissatisfaction within some of London's more disadvantaged neighbourhoods, but also identifies a need for policies that are grounded in cross-disciplinary research into the relationship between health, 'wellbeing' and experiences of marginalisation among urban populations.

  7. Environmental Risk Factors influencing Bicycle Theft: A Spatial Analysis in London, UK

    Science.gov (United States)

    Helbich, Marco

    2016-01-01

    Urban authorities are continuously drawing up policies to promote cycling among commuters. However, these initiatives are counterproductive for the targeted objectives because they increase opportunities for bicycle theft. This paper explores Inner London as a case study to address place-specific risk factors for bicycle theft at the street-segment level while controlling for seasonal variation. The presence of certain public amenities (e.g., bicycle stands, railway stations, pawnshops) was evaluated against locations of bicycle theft between 2013 and 2016 and risk effects were estimated using negative binomial regression models. Results showed that a greater level of risk stemmed from land-use facilities than from area-based socioeconomic status. The presence of facilities such as train stations, vacant houses, pawnbrokers and payday lenders increased bicycle theft, but no evidence was found that linked police stations with crime levels. The findings have significant implications for urban crime prevention with respect to non-residential land use. PMID:27643788

  8. Highlights from Faraday Discussion: Designing New Heterogeneous Catalysts, London, UK, April 2016.

    Science.gov (United States)

    Fischer, Nico; Manyar, Haresh G; Roldan, Alberto

    2016-06-28

    The Faraday Discussion on the design of new heterogeneous catalysts took place from 4-6 April 2016 in London, United Kingdom. It brought together world leading scientists actively involved in the synthesis, characterisation, modelling and testing of solid catalysts, attracting more than one hundred delegates from a broad spectrum of backgrounds and experience levels - academic and industrial researchers, experimentalists and theoreticians, and students. The meeting was a reflection of how big of an impact the ability to control and design catalysts with specific properties for particular processes can potentially have on the chemical industry, environment, economy and society as a whole. In the following, we give an overview of the topics covered during this meeting and briefly highlight the content of each presentation.

  9. Discovery of previously unrecognised local faults in London, UK, using detailed 3D geological modelling

    Science.gov (United States)

    Aldiss, Don; Haslam, Richard

    2013-04-01

    In parts of London, faulting introduces lateral heterogeneity to the local ground conditions, especially where construction works intercept the Palaeogene Lambeth Group. This brings difficulties to the compilation of a ground model that is fully consistent with the ground investigation data, and so to the design and construction of engineering works. However, because bedrock in the London area is rather uniform at outcrop, and is widely covered by Quaternary deposits, few faults are shown on the geological maps of the area. This paper discusses a successful resolution of this problem at a site in east central London, where tunnels for a new underground railway station are planned. A 3D geological model was used to provide an understanding of the local geological structure, in faulted Lambeth Group strata, that had not been possible by other commonly-used methods. This model includes seven previously unrecognised faults, with downthrows ranging from about 1 m to about 12 m. The model was constructed in the GSI3D geological modelling software using about 145 borehole records, including many legacy records, in an area of 850 m by 500 m. The basis of a GSI3D 3D geological model is a network of 2D cross-sections drawn by a geologist, generally connecting borehole positions (where the borehole records define the level of the geological units that are present), and outcrop and subcrop lines for those units (where shown by a geological map). When the lines tracing the base of each geological unit within the intersecting cross-sections are complete and mutually consistent, the software is used to generate TIN surfaces between those lines, so creating a 3D geological model. Even where a geological model is constructed as if no faults were present, changes in apparent dip between two data points within a single cross-section can indicate that a fault is present in that segment of the cross-section. If displacements of similar size with the same polarity are found in a series

  10. Fear of crime, mobility and mental health in inner-city London, UK.

    Science.gov (United States)

    Whitley, Rob; Prince, Martin

    2005-10-01

    This paper examines the relationship between fear of crime and mental health, and assesses the role interventions may have in helping overcome any negative impact arising from this fear. The data were gathered over a 2-year period in the Gospel Oak neighbourhood of North London using in-depth interviews, focus groups and participant observation. The data are analysed primarily by comparing the impact of fear of crime across sub-groups notably divided by gender, age and mental health status. It was found that fear of crime had a disproportionately negative impact on certain sub-groups, most notably low-income mothers, and to a lesser extent the mentally ill. They experienced what we term "time-space inequalities" as a consequence of fear of crime and other related factors. These inequalities describe variation in the ability to access and utilise different times and spaces within both the immediate and the wider environment. These have negative behavioural and affective consequences that appear to impact on overall mental health. They restrict spatial and temporal movement deterring protective social activity, health-promoting community involvement and use of services. Affective consequences include negative mood and low self-esteem. These inequalities were experienced less in other groups such as mentally healthy men or middle-income women. They appeared to be diminished by interventions that encourage spatial and temporal movement. These include comprehensive local transport, government-issued free travel passes for vulnerable populations and neighbourhood community safety measures such as the installation of CCTV. We suggest that experience of time-space inequalities may be damaging to mental health and that interventions which lessen them may help prevent, ameliorate or shorten episodes of mental illness.

  11. How and Why Do Smokers Start Using E-Cigarettes? Qualitative Study of Vapers in London, UK

    Directory of Open Access Journals (Sweden)

    Elle Wadsworth

    2016-06-01

    Full Text Available The aims of the study were to (1 describe how and why smokers start to vape and what products they use; (2 relate findings to the COM-B theory of behaviour change (three conditions are necessary for behaviour change (B: capability (C, opportunity (O, and motivation (M; and (3 to consider implications for e-cigarette policy research. Semi-structured interviews (n = 30 were conducted in London, UK, with smokers or ex-smokers who were currently using or had used e-cigarettes. E-cigarette initiation (behaviour was facilitated by: capability (physical capability to use an e-cigarette and psychological capability to understand that using e-cigarettes was less harmful than smoking; opportunity (physical opportunity to access e-cigarettes in shops, at a lower cost than cigarettes, and to vape in “smoke-free” environments, as well as social opportunity to vape with friends and family; and motivation (automatic motivation including curiosity, and reflective motivation, including self-conscious decision-making processes related to perceived health benefits. The application of the COM-B model identified multiple factors that may lead to e-cigarette initiation, including those that could be influenced by policy, such as price relative to cigarettes and use in smoke-free environments. The effects of these policies on initiation should be further investigated along with the possible moderating/mediating effects of social support.

  12. Liminal identities: Caribbean men who have sex with men in London, UK.

    Science.gov (United States)

    Anderson, Moji; Elam, Gillian; Gerver, Sarah; Solarin, Ijeoma; Fenton, Kevin; Easterbrook, Phillippa

    2009-04-01

    Accounts by 10 Caribbean men who have sex with men living in the UK reveal them to be liminal beings with unstable and unresolved identities. They are between social states: aware they are not heterosexual and not publicly recognised, or in some cases self-accepted, as homosexual. Caribbean-born respondents especially suffer from homophobia, expressing regret and disappointment at their sexuality. They may also experience cognitive dissonance - as they are aware of their conflict with the heteronormative order - they cannot resolve. Religion contributes to homophobia and cognitive dissonance particularly for Caribbean-born men, some of whom may believe a fundamental conflict exists between Christianity and homosexuality. Heterosexism and homophobia contribute to and reinforce their liminal state, by preventing transition to publicly recognised homosexual status. Respondents may engage in private and public, internal and external, overt and covert policing of their and other gay men's behaviour: through strategic pretence at heterosexuality and/or condemnation of men engaging in behaviour identifiable as stereotypically homosexual, for example. Narratives point to the need to complexify the conventional understanding of Jamaican heterosexism to explain reported variations in the degree of anti-homosexual hostility in the country.

  13. Methanotrophy in London, UK, Landfill Topsoil: Microbiology, Stable Carbon Isotopes, Seasonal Variation and Laboratory Model Study

    Science.gov (United States)

    Sriskantharajah, S.; Fisher, R.; Lowry, D.; Grassineau, N.; Nisbet, E. G.

    2004-12-01

    Landfill is a major source of methane emissions into the atmosphere. Aerobic soil is also a good sink of methane, as it is inhabited by methane consuming bacteria, methanotrophs. Methanotrophic bacteria were cultured from landfill soil samples. Three genera of methanotrophs were cultured: Methylocaldum, Methylosinus and Methylomonas. Interestingly, the only established members of the Methylocaldum genus are all thermophilic, whilst those isolated in this study are mesophilic. This suggests that those Methylocaldum methanotrophs found in landfills may have migrated from hot spring natural settings. Representatives of each genera were inoculated into a simple topsoil model and subjected to variations in temperature, methane concentration and incubation periods. As expected, temperature greatly affected methane oxidation, but methane concentration affected the rate of oxidation far more than expected. The model study implies that the complete combustion of methane to carbon dioxide is greatly affected by temperature and methane availability, whilst the effect on the uptake of methane is not as great. Seasonal variations in methane concentrations within the topsoil were monitored over a one year period from November 2002 to October 2003 and show that methane flow through the topsoil, and consequently methanotrophy, is strongly controlled by meteorology, mainly air temperature and pressure. Generally, methanotrophy was low during colder months and higher at during warmer months, but changes in air pressure complicate this by controlling the rate of flow of methane through the topsoil. δ 13C analyses of methane and carbon dioxide emitted from landfill topsoil showed that there was a great deal of methanotrophic activity during the warmer months of 2003, with most fractionation of residual methane occurring during August. During the heat wave experienced in the UK in August 2003, the δ 13C from borehole samples of methane in the anaerobic zone shifted from -57‰ to -16

  14. Antibiotic resistance and mecA characterization of coagulase-negative staphylococci isolated from three hotels in London, UK.

    Science.gov (United States)

    Xu, Zhen; Mkrtchyan, Hermine V; Cutler, Ronald R

    2015-01-01

    Antibiotic resistance in bacteria isolated from non-healthcare environments, is a potential problem to public health. In our survey a total of 71 coagulase negative staphylococci (CNS) belonging to 11 different species were isolated from three large hotels in London, UK. The most prevalent species was Staphylococcus haemolyticus, with S. hominis, S. warneri, S. cohnii, and Staphylococcus epidermidis commonly detected. Antimicrobial susceptibilities and carriage of the mecA gene were determined for all of these isolates. Most (85.9%) staphylococci were resistant to multiple antibiotics with all displaying increased susceptibility toward penicillin, fusidic acid, erythromycin, and cefepime. Twenty-one (29.5%) of the isolates were mecA positive, however MIC values to oxacillin, normally associated with the carriage of mecA, varied widely in this group (from 0.06 to 256 mg/L). Fifteen of the twenty-one mecA positive isolates carried SCCmec of these seven were type V, one type I, one type II, and one type IV. Additionally, five of these 15 isolates carried a previously unreported type, 1A, which involves an association between class A mec complex and ccr type 1. The remaining six of the 21 isolates were non-typeable and carried a combination of class A mec complex and ccrC. In addition to this, we also report on new MLST types which were assigned for five S. epidermidis isolates. Four out of these five isolates had MICs between 0.06 and 256 mg/L to oxacillin and would be regarded as clinically susceptible but one isolate had a high oxacillin MIC of 256 mg/L. We demonstrated widespread multiple drug resistance among different staphylococcal species isolated from non-healthcare environments highlighting the potential for these species to act as a reservoir for methicillin and other forms of drug resistance.

  15. Antibiotic resistance and mecA characterization of coagulase-negative staphylococci isolated from three hotels in London, UK

    Directory of Open Access Journals (Sweden)

    Zhen eXu

    2015-09-01

    Full Text Available Antibiotic resistance in bacteria isolated from non–healthcare environments, is a potential problem to public health. In our survey a total of 71 coagulase negative staphylococci belonging to 11 different species were isolated from 3 large hotels in London, UK. The most prevalent species was Staphylococcus haemolyticus, with S. hominis, S. warneri, S.cohnii and S. epidermidis commonly detected. Antimicrobial susceptibilities and carriage of the mecA gene were determined for all of these isolates. Most (85.9% staphylococci were resistant to multiple antibiotics with all displaying increased susceptibility towards penicillin, fusidic acid, erythromycin and cefepime. 21 (29.5% of the isolates were mecA positive, however MIC values to oxacillin, normally associated with the carriage of mecA, varied widely in this group (from 0.06 mg/L to 256 mg/L. 15 of the 21 mecA positive isolates carried SCCmec of these 7 were type V, 1 type I, 1 type II and 1 type IV. Additionally, five of these 15 isolates carried a previously unreported type, 1A, which involves an association between class A mec complex and ccr type 1. The remaining 6 of the 21 isolates were non-typeable and carried a combination of class A mec complex and ccrC. In addition to this, we also report on new MLST types which were assigned for 5 Staphylococcus epidermidis isolates. 4 out of these 5 isolates had MICs between 0.06 to 256 mg/L to oxacillin and would be regarded as clinically susceptible but one isolate had a high oxacillin MIC of 256 mg/L. We demonstrated widespread multiple drug resistance among different staphylococcal species isolated from non-healthcare environments highlighting the potential for these species to act as a reservoir for methicillin and other forms of drug resistance.

  16. Handsearching the EMHJ for reports of randomized controlled trials by U.K. Cochrane Centre (Bahrain).

    Science.gov (United States)

    Al Hajeri, A; Al Sayyad, J; Eisinga, A

    2006-01-01

    This study used handsearching to find reports of randomized controlled trials in the Eastern Mediterranean Health Journal (EMHJ). EMBASE and MEDLINE were also searched electronically to identify if the reports found by the handsearch were already included in either of these databases. Nine reports were identified: 7 randomized controlled trials and 2 controlled clinical trials. The added value of the handsearch over EMBASE was 6 additional reports and over MEDLINE was 4. Reports identified were sent to the UK Cochrane Centre for verification and publication in The Cochrane Central Register of Controlled Trials (CENTRAL).

  17. The South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLAM BRC case register: development and descriptive data

    Directory of Open Access Journals (Sweden)

    Denis Mike

    2009-08-01

    Full Text Available Abstract Background Case registers have been used extensively in mental health research. Recent developments in electronic medical records, and in computer software to search and analyse these in anonymised format, have the potential to revolutionise this research tool. Methods We describe the development of the South London and Maudsley NHS Foundation Trust (SLAM Biomedical Research Centre (BRC Case Register Interactive Search tool (CRIS which allows research-accessible datasets to be derived from SLAM, the largest provider of secondary mental healthcare in Europe. All clinical data, including free text, are available for analysis in the form of anonymised datasets. Development involved both the building of the system and setting in place the necessary security (with both functional and procedural elements. Results Descriptive data are presented for the Register database as of October 2008. The database at that point included 122,440 cases, 35,396 of whom were receiving active case management under the Care Programme Approach. In terms of gender and ethnicity, the database was reasonably representative of the source population. The most common assigned primary diagnoses were within the ICD mood disorders (n = 12,756 category followed by schizophrenia and related disorders (8158, substance misuse (7749, neuroses (7105 and organic disorders (6414. Conclusion The SLAM BRC Case Register represents a 'new generation' of this research design, built on a long-running system of fully electronic clinical records and allowing in-depth secondary analysis of both numerical, string and free text data, whilst preserving anonymity through technical and procedural safeguards.

  18. Characteristics and practices of Traditional Chinese Medicine retail shops in London, UK: A cross-sectional study using an observational approach.

    Science.gov (United States)

    Teng, Lida; Shaw, Debbie; Barnes, Joanne

    2015-09-15

    Traditional Chinese Medicine (TCM) is a popular form of ethnomedicine in the UK, and is accessed by Western, Chinese and other ethnic groups. The current regulatory regime does not effectively protect the public against poor-quality and unsafe TCMs. Understanding ethnopharmacological information on how TCM is promoted and practiced may help to inform initiatives aimed at ensuring the safe use of TCMs in the UK, and put laboratory-based ethnopharmacological investigations of TCMs in a broader context. This study aimed to examine the characteristics and practices of TCM retail outlets in London, UK, and to identify factors relevant to the safe use of TCM in the UK. TCM retail outlets ('shops') in London, UK, were identified using a systematic approach. A structured questionnaire including questions on shop business type was used to recruit participant shops. Shops consenting to participate were visited within six weeks of providing consent. A piloted semi-structured questionnaire on shop characteristics was used for data collection following observation. The British National Formulary 53 was used to classify medical conditions/uses for TCMs promoted in the shops. Data were stored and analysed using MS Access 2003, MS Excel 2003 and SPSS 13. In total, 54 TCM shops in London were identified, of which 94% offered TCM consultations with a TCM practitioner. Detailed characteristics were described within 35/50 shops that gave consent to observing their premises. Most shops labelled and displayed over 150 Chinese Materia Medica (CMMs; crude materials, particularly herbs) for dispensing after consultations with a TCM practitioner. Medical conditions/uses and Patent Chinese Medicines (PCMs) were commonly promoted. In total, 794 occurrences of 205 different medical conditions/uses (median=32, QL=19, QU=48) were identified. These conditions/uses most commonly related to the following therapeutic systems: central nervous system (160/794, 20.2%); musculoskeletal and joint disease

  19. Are fuel poverty reduction schemes associated with decreased excess winter mortality in elders? A case study from London, U.K.

    Science.gov (United States)

    El Ansari, Walid; El-Silimy, Sally

    2008-12-01

    The London Borough of Newham, London piloted the Warm Zone, a government-led fuel poverty reduction scheme. Fuel poverty is often cited as a factor in excess winter mortality (EWM) in the U.K. This study reported in this paper assessed whether EWM decreased for people aged > or =65 years in Newham as compared to all London, employing data from before and throughout the duration of the Warm Zone project. The paper also discusses the difficulties surrounding the measurement and interpretation of health impact relating to fuel poverty. We calculated and compared the yearly EWM indices for people aged > or =65 years for all of London, and for Newham over 12 years (1993-2005). The yearly EWM ratio for Newham in relation to all London was then calculated and compared. No definitive evidence to support the effect of the War Zone on EMW were noted. Relationships between EWM and fewer poverty reduction schemes are difficult to interpret, as many factors are entangled. These include cold strain and biological, genetic, gender, physiological, thermoregulation, environmental, meteorological, socio-economic, healthcare provision/expenditure, lifestyle and co-morbidity aspects, besides the challenges of sample sizes and whether other fuel poverty reduction schemes were simultaneously in operation. Those in privately owned housing might be ;masked' (underestimated) in their vulnerability to fuel poverty. Redefining the specific criteria for eligibility for fuel poverty grants and tackling heat inefficiency in privately owned homes not eligible for home heating improvement despite fulfilling other criteria for vulnerability requires attention. The implications are discussed.

  20. Infectious canine hepatitis in red foxes (Vulpes vulpes) in wildlife rescue centres in the UK.

    Science.gov (United States)

    Walker, D; Abbondati, E; Cox, A L; Mitchell, G B B; Pizzi, R; Sharp, C P; Philbey, A W

    2016-04-23

    Outbreaks of infectious canine hepatitis are described in red foxes ( ITALIC! Vulpes vulpes) at two wildlife rescue centres in the UK. Disease occurred in two-month-old to four-month-old juvenile foxes, which were held in small enclosures in groups of three to eight animals. The foxes died or were euthanased after a short clinical course, sometimes including neurological signs and jaundice, with a high case fatality rate. Four red foxes submitted for postmortem examination had enlarged, congested livers, with rounded borders and mild accentuation of the lobular pattern. On histological examination, there was random, multifocal to massive hepatic necrosis, along with multifocal vasculitis in the central nervous system (CNS) and mild, multifocal glomerulonephritis. Intranuclear inclusion bodies, typical of canine adenovirus type 1 (CAV-1) infection, were present in hepatocytes, vascular endothelial cells in the CNS, renal glomeruli and renal tubular epithelial cells. CAV-1 was detected in tissues from affected foxes by PCR and sequencing. Congregation of juvenile foxes in wildlife rescue centres is likely to be a risk factor for transmission of CAV-1. Preventive measures in wildlife centres should be implemented to prevent the spread of the virus among conspecifics and to other susceptible species.

  1. Model simulations of cooking organic aerosol (COA) over the UK using estimates of emissions based on measurements at two sites in London

    Science.gov (United States)

    Ots, Riinu; Vieno, Massimo; Allan, James D.; Reis, Stefan; Nemitz, Eiko; Young, Dominique E.; Coe, Hugh; Di Marco, Chiara; Detournay, Anais; Mackenzie, Ian A.; Green, David C.; Heal, Mathew R.

    2016-11-01

    Cooking organic aerosol (COA) is currently not included in European emission inventories. However, recent positive matrix factorization (PMF) analyses of aerosol mass spectrometer (AMS) measurements have suggested important contributions of COA in several European cities. In this study, emissions of COA were estimated for the UK, based on hourly AMS measurements of COA made at two sites in London (a kerbside site in central London and an urban background site in a residential area close to central London) for the full calendar year of 2012 during the Clean Air for London (ClearfLo) campaign. Iteration of COA emissions estimates and subsequent evaluation and sensitivity experiments were conducted with the EMEP4UK atmospheric chemistry transport modelling system with a horizontal resolution of 5 km × 5 km. The spatial distribution of these emissions was based on workday population density derived from the 2011 census data. The estimated UK annual COA emission was 7.4 Gg per year, which is an almost 10 % addition to the officially reported UK national total anthropogenic emissions of PM2.5 (82 Gg in 2012), corresponding to 320 mg person-1 day-1 on average. Weekday and weekend diurnal variation in COA emissions were also based on the AMS measurements. Modelled concentrations of COA were then independently evaluated against AMS-derived COA measurements from another city and time period (Manchester, January-February 2007), as well as with COA estimated by a chemical mass balance model of measurements for a 2-week period at the Harwell rural site (˜ 80 km west of central London). The modelled annual average contribution of COA to ambient particulate matter (PM) in central London was between 1 and 2 µg m-3 (˜ 20 % of total measured OA1) and between 0.5 and 0.7 µg m-3 in other major cities in England (Manchester, Birmingham, Leeds). It was also shown that cities smaller than London can have a central hotspot of population density of smaller area than the

  2. Before the ban--an exploratory study of a local khat market in East London, U.K.

    Science.gov (United States)

    Kassim, Saba; Dalsania, Asha; Nordgren, Johan; Klein, Axel; Hulbert, Josh

    2015-06-12

    Khat is a green leaf with amphetamine-like effects. It is primarily used among people in Africa, the Middle East and in the diaspora communities from these countries. Prior to the prohibition of khat in the UK on 24 June 2014, there was almost no information available on key aspects of the local khat market. A cross-sectional study was conducted in 2012 using snowball sampling, Privileged Access Interviewing and area mapping in order to identify khat sale establishments. Data was collected via face-to-face interviews using mixed methods for data collection. This included information about the establishments selling khat, khat pricing and its use among different ethnic minority groups, in addition to the potential sale of khat to children and risk assessment (e.g., use of pesticides on khat). Five out of seven sellers identified agreed to participate. Sellers described their khat sale establishments as 'community centres' which included, for example, a restaurant basement. The sellers' history of selling khat ranged between 1-15 years and khat's sale took place between 2pm-10pm. Miraa (e.g., Lara) from Kenya was the most popularly used khat variety, sold in pre-wrapped bundles of approximately 250 g costing £3 each and delivered four days a week. Harari (e.g., Owdi) from Ethiopia was sold in 200 g, 400 g and 1 kg bundles, priced between £5 and £20 and delivered two days a week. The primary benefit of khat use was reported to be social interaction. The customers were predominantly adult males of Somali origin. Most sellers claimed a self-imposed ban on sales to children under 18 years old. Khat bundles had no labelling describing variety or weight and sellers had no knowledge of the use of pesticides on khat and did not advertise the risks associated with khat use. Khat selling establishments were businesses that did not adhere to trade standards regulations (e.g., labelling khat bundles). They claimed to provide a community service (facilitating social

  3. "That's your patient. There's your ventilator": exploring induction to work experiences in a group of non-UK EEA trained anaesthetists in a London hospital: a qualitative study.

    Science.gov (United States)

    Snelgrove, Huon; Kuybida, Yuriy; Fleet, Mark; McAnulty, Greg

    2015-03-17

    European health systems depend increasingly on the services of health professionals who obtained their primary medical qualification from other countries. There has been a significant increase recently in fully qualified specialist doctors arriving from the European Union to provide short term or longer-term solutions to health human resources needs in the UK National Health System. These doctors often take up senior consultant positions. As a result, the NHS has had to learn to deal with both expatriation and repatriation of EU doctors as a constant dynamic characteristic of its own ability to deliver services. We conducted a qualitative study to explore the acclimatisation experience of EU doctors with qualifications in anaesthesia arriving in the United Kingdom to take up clinical employment in the NHS. The question we ask is: how do specialty registered anaesthetists who trained in other European countries experience the process of acclimatisation to practice in the United Kingdom in a large hospital in London? We did individual interviews with non-UK, EU-qualified doctors with Certification of Completion of specialty Training who were registered with the General Medical Council in the UK and could practice in the NHS as specialist anaesthetists. The doctors were all interviewed whilst working in a large NHS teaching hospital in London, UK. We analysed qualitative data from interview transcripts to identity themes and patterns regarding senior doctor's acclimatisation to the British system. Acclimatisation conceived of as transfer of clinical expertise was problematic for doctors who felt they lacked the right kind of support. Doctors sought different opportunities to share wider perspectives on care deriving from their previous experience. Hospital conceptions of acclimatisation as a highly individual process can offer an idealized view of clinical work and learning in the new system. Socio-cultural theories suggest we create regular learning opportunities for

  4. Oral health and oral health behaviours of five-year-old children in the Charedi Orthodox Jewish Community in North London, UK.

    Science.gov (United States)

    Klass, C; Mondkar, A; Wright, D

    2017-03-01

    To report on the oral health status and oral health behaviours of five-year-old Charedi Orthodox Jewish children attending schools in London, UK. Cross-sectional survey. Clinical examinations mirroring the 2015 National Dental Public Health Epidemiology Programme for England for five-year-olds and a parental questionnaire on oral health behaviours. 137 five-year-olds attending Charedi Orthodox Jewish schools in Hackney, North London. Prevalence dmft⟩0 (%) and severity (mean dmft) of dental caries. Of these children 58% had experienced dental caries (95%CI 50,67), the mean number of decayed, missing and filled teeth was 2.38 (95%CI 1.90,2.82) and 23% (95%CI 16,30) had caries affecting their incisors. Only 20% reported that their children had their teeth brushed twice a day and 16% of the children started having their teeth brushed between six months and one year of age. The oral health of five-year-old children in the Charedi Orthodox Jewish community is significantly worse than their counterparts across Hackney, London and England. The establishment of robust baseline data supports the local authority plan to develop targeted oral health improvement programmes tailored to address the health needs and cultural sensitivities of this community. Copyright© 2017 Dennis Barber Ltd.

  5. Mechanisms, patterns and outcomes of paediatric polytrauma in a UK major trauma centre.

    Science.gov (United States)

    Naqvi, G; Johansson, G; Yip, G; Rehm, A; Carrothers, A; Stöhr, K

    2017-01-01

    Introduction Paediatric trauma is a significant burden to healthcare worldwide and accounts for a large proportion of deaths in the UK. Methods This retrospective study examined the epidemiological data from a major trauma centre in the UK between January 2012 and December 2014, reviewing all cases of moderate to severe trauma in children. Patients were included if aged ≤16 years and if they had an abbreviated injury scale score of ≥2 in one or more body region. Results A total of 213 patients were included in the study, with a mean age of 7.8 years (standard deviation [SD]: 5.2 years). The most common cause of injury was vehicle related incidents (46%). The median length of hospital stay was 5 days (interquartile range [IQR]: 4-10 days). Approximately half (52%) of the patients had to stay in the intensive care unit, for a median of 1 day (IQR: 0-2 days). The mortality rate was 6.6%. The mean injury severity score was 19 (SD: 10). Pearson's correlation coefficient showed a positive correlation for injury severity score with length of stay in hospital (p<0.001). Conclusions There is significant variation in mechanism of injury, severity and pattern of paediatric trauma across age groups. A multidisciplinary team approach is imperative, and patients should be managed in specialist centres to optimise their care and eventual functional recovery. Head injury remained the most common, with significant mortality in all age groups. Rib fractures and pelvic fractures should be considered a marker for the severity of injury, and should alert doctors to look for other associated injuries.

  6. Pregnancy outcomes in sickle cell disease: a retrospective cohort study from two tertiary centres in the UK

    OpenAIRE

    Chase, A. R.; Sohal, M; Howard, J.; Laher, R.; McCarthy, A; Layton, D. M.; Oteng-Ntim, E.

    2010-01-01

    The objective of this retrospective cohort study from two tertiary centres in the UK was to describe the pregnancy outcomes of women with sickle cell disease (SCD) who booked at these centres between 2004 and 2008, and to compare this with historical data. The study population comprised 122 singleton pregnancies in women with SCD: homozygous sickle cell disease 64, sickle cell haemoglobin C disease 45, sickle b plus thalassaemia 11, sickle cell haemoglobin E disease 1 and sickle cell delta di...

  7. Improving the installation of renewable heating technology in UK social housing properties through user centred design.

    Science.gov (United States)

    Moore, Natalie; Haines, Victoria; Lilley, Debra

    2015-11-01

    Social housing organisations are increasingly installing renewable energy technologies, particularly for the provision of heating and hot water. To meet carbon reduction targets, uptake and installation must allow occupants to use the technology effectively. This paper describes research which investigated the service of installing heat pumps into UK social housing properties, from both landlords' and tenants' experiences. Adopting a user centred design approach, the research was in three phases: an exploration study to investigate landlords' and tenants' experiences of heat pump installation and use; refinement and development of the requirements for improved service delivery, primarily technology introduction and control; and the development and initial evaluation of an information leaflet as a key touchpoint in the service delivery. Recommendations for improved service delivery, to enable heat pumps to be accepted and used more effectively, are presented, as well as reflection on the process of applying user centred design in this context. In a relatively immature area of industry, installations to date have been heavily focused on technical aspects. This paper provides an insight into the human aspects of the service delivery of heat pumps in social housing, providing designers and social housing landlords with insight about how to improve the service.

  8. 20th ANNIVERSARY OF THE CHILDREN'S HEALTH AND EXERCISE CENTRE, UNIVERSITY OF EXETER, UK

    Directory of Open Access Journals (Sweden)

    Craig Sharp

    2007-09-01

    Full Text Available 20th ANNIVERSARY OF THE CHILDREN'S HEALTH AND EXERCISE CENTRE, UNIVERSITY OF EXETER, UK In recent years, partly because of the ever-younger exten-sion of high quality sport representation and partly, para-doxically, due to ever-increasing levels of obesity in the young, the discipline of paediatric physiology has moved from being an interesting curiosity to an extremely impor-tant area of practical knowledge. For example, children thermoregulate qualitatively and quantitatively differently from adults - before puberty their sweat rate per square metre of skin is less than half their adult level - and they may well have, proportionate to mass, 40% greater body surface area than an adult. On the musculo-skeletal side, they come late into 'kinetic-balance', into an appropriately economic mode of running or walking, so such effort is harder for them. In many other areas children, especially younger children, differ importantly from adults, and those involved in any aspects of their exercise, sport or medicine should be well aware of this. Hence the impor-tance of the discipline, and hence the reason for a very hearty celebration of the 20th anniversary of the Chil-dren's Health and Exercise Centre (CHERC, which, as is demonstrated here, has pioneered and expanded the entire discipline, as one of the world's leading paediatric labora-tories.To celebrate the 20th anniversary of the Children's Health and Exercise Centre (1987-2007 past and present mem-bers of the centre were invited to contribute a review article on paediatric exercise science. The collection of reviews, written by current and former PhD students, visiting research fellows and professors, visiting interns and current members of CHERC, discusses an array of topics, which have helped shaped the work of our centre. We would also like to take the opportunity to acknowl-edge all those associated with CHERC over the past 20 years, in particular the many children who have partici-pated in our

  9. Provision of cellular blood components to CMV-seronegative patients undergoing allogeneic stem cell transplantation in the UK: survey of UK transplant centres.

    Science.gov (United States)

    Morton, S; Peniket, A; Malladi, R; Murphy, M F

    2017-09-15

    To identify current UK practice with regards to provision of blood components for cytomegalovirus (CMV)-seronegative, potential, allogeneic stem cell recipients of seronegative grafts. Infection with CMV remains a major cause of morbidity and mortality after allogeneic stem cell transplantation (aSCT). CMV transmission has been a risk associated with the transfusion of blood components from previously exposed donors, but leucocyte reduction has been demonstrated to minimise this risk. In 2012, the UK Advisory Committee for the Safety of Tissues and Organs (SaBTO) recommended that CMV-unselected components could be safely transfused without increased risk of CMV transmission. We surveyed UK aSCT centres to establish current practice. Fifteen adult and seven paediatric centres (75%) responded; 22·7% continue to provide components from CMV-seronegative donors. Reasons cited include the continued perceived risk of CMV transmission by blood transfusion, its associated morbidity and concerns regarding potential for ambiguous CMV serostatus in seronegative potential transplant recipients due to passive antibody transfer from CMV-seropositive blood donors, leading to erroneous donor/recipient CMV matching at transplant. The survey demonstrated a surprisingly high rate (22.7%) of centres continuing to provide blood components from CMV-seronegative donors despite SaBTO guidance. © 2017 British Blood Transfusion Society.

  10. Lessons for control of heroin-associated anthrax in Europe from 2009-2010 outbreak case studies, London, UK.

    Science.gov (United States)

    Abbara, Aula; Brooks, Tim; Taylor, Graham P; Nolan, Marianne; Donaldson, Hugo; Manikon, Maribel; Holmes, Alison

    2014-07-01

    Outbreaks of serious infections associated with heroin use in persons who inject drugs (PWIDs) occur intermittently and require vigilance and rapid reporting of individual cases. Here, we give a firsthand account of the cases in London during an outbreak of heroin-associated anthrax during 2009-2010 in the United Kingdom. This new manifestation of anthrax has resulted in a clinical manifestation distinct from already recognized forms. During 2012-13, additional cases of heroin-associated anthrax among PWIDs in England and other European countries were reported, suggesting that anthrax-contaminated heroin remains in circulation. Antibacterial drugs used for serious soft tissue infection are effective against anthrax, which may lead to substantial underrecognition of this novel illness. The outbreak in London provides a strong case for ongoing vigilance and the use of serologic testing in diagnosis and serologic surveillance schemes to determine and monitor the prevalence of anthrax exposure in the PWID community.

  11. Materials modelling in London

    Science.gov (United States)

    Ciudad, David

    2016-04-01

    Angelos Michaelides, Professor in Theoretical Chemistry at University College London (UCL) and co-director of the Thomas Young Centre (TYC), explains to Nature Materials the challenges in materials modelling and the objectives of the TYC.

  12. Estimating the influence of different urban canopy cover types on atmospheric particulate matter (PM10) pollution abatement in London UK.

    Science.gov (United States)

    Tallis, Matthew; Freer-Smith, Peter; Sinnett, Danielle; Aylott, Matthew; Taylor, Gail

    2010-05-01

    In the urban environment atmospheric pollution by PM10 (particulate matter with a diameter less than 10 x 10-6 m) is a problem that can have adverse effects on human health, particularly increasing rates of respiratory disease. The main contributors to atmospheric PM10 in the urban environment are road traffic, industry and power production. The urban tree canopy is a receptor for removing PM10s from the atmosphere due to the large surface areas generated by leaves and air turbulence created by the structure of the urban forest. In this context urban greening has long been known as a mechanism to contribute towards PM10 removal from the air, furthermore, tree canopy cover has a role in contributing towards a more sustainable urban environment. The work reported here has been carried out within the BRIDGE project (SustainaBle uRban plannIng Decision support accountinG for urban mEtabolism). The aim of this project is to assess the fluxes of energy, water, carbon dioxide and particulates within the urban environment and develope a DSS (Decision Support System) to aid urban planners in sustainable development. A combination of published urban canopy cover data from ground, airborne and satellite based surveys was used. For each of the 33 London boroughs the urban canopy was classified to three groups, urban woodland, street trees and garden trees and each group quantified in terms of ground cover. The total [PM10] for each borough was taken from the LAEI (London Atmospheric Emissions Inventory 2006) and the contribution to reducing [PM10] was assessed for each canopy type. Deposition to the urban canopy was assessed using the UFORE (Urban Forest Effects Model) approach. Deposition to the canopy, boundary layer height and percentage reduction of the [PM10] in the atmosphere was assessed using both hourly meterological data and [PM10] and seasonal data derived from annual models. Results from hourly and annual data were compared with measured values. The model was then

  13. Report on Proceedings of the Sixth Annual Meeting of the European CME Forum, London, UK, 14–15 November 2013

    Directory of Open Access Journals (Sweden)

    Ron Murray

    2014-01-01

    Full Text Available Delegates from around the world attended the sixth annual meeting of the European CME Forum in London between 14 and 15 November 2013. The participants discussed best practices in continuing medical education and continuing professional development (CME–CPD delivery, reviewed CME provision by various medical specialist societies, and viewed examples of e-CME educational activities in CME–CPD. The details of a new code for disclosure by European pharmaceutical companies were unveiled, and the implications were discussed with expert panels comparing the CME landscape in the United States with that in Europe. Accreditation systems were compared, and a number of informal sessions allowed the delegates to consider issues relevant to physician learners, transparency and accountability in CME planning and implementation, and opportunities for collaboration.

  14. Evaluation of the source area of rooftop scalar measurements in London, UK using wind tunnel and modelling approaches.

    Science.gov (United States)

    Brocklehurst, Aidan; Boon, Alex; Barlow, Janet; Hayden, Paul; Robins, Alan

    2014-05-01

    The source area of an instrument is an estimate of the area of ground over which the measurement is generated. Quantification of the source area of a measurement site provides crucial context for analysis and interpretation of the data. A range of computational models exists to calculate the source area of an instrument, but these are usually based on assumptions which do not hold for instruments positioned very close to the surface, particularly those surrounded by heterogeneous terrain i.e. urban areas. Although positioning instrumentation at higher elevation (i.e. on masts) is ideal in urban areas, this can be costly in terms of installation and maintenance costs and logistically difficult to position instruments in the ideal geographical location. Therefore, in many studies, experimentalists turn to rooftops to position instrumentation. Experimental validations of source area models for these situations are very limited. In this study, a controlled tracer gas experiment was conducted in a wind tunnel based on a 1:200 scale model of a measurement site used in previous experimental work in central London. The detector was set at the location of the rooftop site as the tracer was released at a range of locations within the surrounding streets and rooftops. Concentration measurements are presented for a range of wind angles, with the spread of concentration measurements indicative of the source area distribution. Clear evidence of wind channeling by streets is seen with the shape of the source area strongly influenced by buildings upwind of the measurement point. The results of the wind tunnel study are compared to scalar concentration source areas generated by modelling approaches based on meteorological data from the central London experimental site and used in the interpretation of continuous carbon dioxide (CO2) concentration data. Initial conclusions will be drawn as to how to apply scalar concentration source area models to rooftop measurement sites and

  15. Quality of Life and Unmet Need in People with Psychosis in the London Borough of Haringey, UK

    Directory of Open Access Journals (Sweden)

    Maria Lambri

    2012-01-01

    Full Text Available Objectives. Deinstitutionalization of long-term psychiatric patients produced various community-based residential care facilities. However, inner-city areas have many patients with severe mental illness (SMI as well as deprivation, unemployment, and crime. This makes meeting their community needs complex. We undertook a needs assessment of service provision and consonance between service users’ evaluation of need and by care workers. Design. Cross-sectional study with random sample of SMI service users in four housing settings: rehabilitation units; high-supported; medium-supported; low-supported housing. Setting. London Borough of Haringey. Outcome Measures. 110 SMI service users and 110 keyworkers were interviewed, using Camberwell Assessment of Need; SF-36; Lancashire Quality-of-Life profile; demographic and clinical information. Results. People in “low-support” and “high-support” housing had similar symptom scores, though low support had significantly lower quality of life. Quality of life was positively predicted by self-reported mental-health score and negatively predicted by unmet-need score in whole sample and in medium-support residents. Residents’ and care-workers’ assessments of need differed considerably. Conclusions. Although patients’ housing needs were broadly met, those in low-supported housing fared least well. Attendance to self-reported mental health and unmet social needs to quality of life underpins planning of residential services for those with SMI. Social and personal needs of people in supported housing may be underestimated and overlooked; service providers need to prioritise these if concept of “recovery” is to advance.

  16. London 2012: Medal projection

    OpenAIRE

    2012-01-01

    We project the medal number and medal ranking for the Olympic Games in London in 2012. The largest relative increase is predicted for Brazil (80% more medals) and the UK (+28%). UK will continue to rank 4th. The largest decreases in medal numbers are predicted for Australia (-13%, but remains in 5th place) and the USA (-13%, remains No. 1). Germany should retain a rank of 6th and will win 38 medals (compared to 41 in 2008).

  17. Examining the family-centred approach to genetic testing and counselling among UK Pakistanis: a community perspective.

    Science.gov (United States)

    Darr, A; Small, N; Ahmad, W I U; Atkin, K; Corry, P; Benson, J; Morton, R; Modell, B

    2013-01-01

    WHO advice suggests a family-centred approach for managing the elevated risk of recessively inherited disorders in consanguineous communities, whilst emerging policy recommends community engagement as an integral component of genetic service development. This paper explores the feasibility of the family-centred approach in the UK Pakistani origin community. The study took place within a context of debate in the media, professional and lay circles about cousin marriage causing disability in children. Using qualitative methods, a total of six single-sex focus group discussions (n = 50) were conducted in three UK cities with a high settlement of people of Pakistani origin. Tape-recorded transcripts were analysed using framework analysis. Kinship networks within Pakistani origin communities are being sustained and marriage between close blood relatives continues to take place alongside other marriage options. Study participants were critical of what was perceived as a prevalent notion that cousin marriage causes disability in children. They were willing to discuss cousin marriage and disability, share genetic information and engage with genetic issues. A desire for accurate information and a public informed about genetic issues was articulated whilst ineffective communication of genetic risk information undermined professionals in their support role. This study suggests a community that is embracing change, one in which kinship networks are still active and genetic information exchange is taking place. At the community level, these are conditions supportive of the family-centred approach to genetic testing and counselling.

  18. Patterns of long bone growth in a mid-19th century documented sample of the urban poor from Bethnal Green, London, UK.

    Science.gov (United States)

    Ives, Rachel; Humphrey, Louise

    2017-05-01

    Studies of male and female long bone growth in past populations are limited and usually constrained by the lack of personal identification. This article aimed to evaluate long bone growth in a series of mid-19(th) century documented burials associated with the urban poor from Bethnal Green, London, UK. Maximum diaphyseal lengths from 74 males and 70 females (2 months to 12 years) were compared to modern reference data from North America. Diaphyseal lengths were expressed as a percentage of expected length and an average percentage value was calculated across all available long bones. An index of growth progression was introduced to explore differences in the progress of males and females towards their projected adult size. Deviation from the expected growth attainment was evident in both sexes in the archaeological series by 2-4 months of age. Only 19.4% (28/144) of the children had attained an average long bone length >90% of the predicted mean in the reference series. The percentage of expected growth attainment decreased steadily in both sexes during infancy and early childhood. Overall, females deviated further from their expected growth progression than males. Growth faltering in both males and females was established during infancy (growth. © 2017 Wiley Periodicals, Inc.

  19. Oral health of children with intractable epilepsy attending the UK National Centre for Young People with Epilepsy.

    Science.gov (United States)

    Percival, T; Aylett, S E; Pool, F; Bloch-Zupan, A; Roberts, G J; Lucas, V S

    2009-01-01

    To investigate the oral health of children with intractable epilepsy attending the UK National Centre for Young People with Epilepsy. 39 children and adolescents with intractable epilepsy at a residential school, the UK National Centre For Young People With Epilepsy (NCYPE) were age, gender and ethnicity matched with 39 healthy children from local schools in Surrey (England). Dental examinations were completed for indices for both the primary and permanent dentitions comprising decayed, missing and filled teeth and surfaces, plaque index, gingivitis index, developmental enamel defects, and incisor tooth trauma. There was no significant difference in the dmfs, dmft, DMFS or DMFT in the children with epilepsy compared with the controls. There was a significantly greater mean plaque score associated with permanent teeth in the children with epilepsy 68.0 SD+/- 31.5, compared with the control children, 142.9 SD+/- 23.2, pepilepsy 47.9+/-33.8, compared with the control children, 15.85+/-21.8, pepilepsy had experienced anterior tooth trauma, 54% in all, compared with the controls, 12.5% pepilepsy had greater mean plaque and gingivitis scores, the prevalence of dental caries was low. Children and teenagers with intractable epilepsy were more likely to have sustained dental trauma than controls. A dental service aimed at early attention to anterior tooth trauma is needed. In addition, there is an ongoing need for improving the oral hygiene of these individuals to prevent the development of periodontal disease in later life.

  20. The London 2012 Olympic and Paralympic Games Olympic—Intelligence Centre: Lessons Learned from Working with the Olympic Sponsors and the Private Sector

    Directory of Open Access Journals (Sweden)

    Sue Wilkinson

    2013-06-01

    Full Text Available This paper is a reflective discussion that critically describes the role of the Olympic Intelligence Centre (OIC played in the delivery of a safe and secure London 2012 Olympic and Paralympic Games. In particular, it examines how the OIC worked with the Olympic Sponsors and the wider private sector to provide them with the classified intelligence and information they needed to play their role in the safety and security operation effectively. Issues discussed include the cultural, statutory and systemic challenges that had to be overcome; how relationships were built to allay concerns and build trust and confidence; and the process that was put into place to allow the exchange of classified intelligence that supported the Sponsors and private sector in their operation. It details how the OIC worked with Sponsors to allow them in turn to exchange intelligence they held in their systems with the OIC, thus completing the intelligence cycle, enhancing the security operation. The article concludes with an outline of the lessons learned that were deduced through a reflective process and are offered to practitioners for consideration in future intelligence work involving the private sector.

  1. Cochlear-implanted children from homes where English is an additional language: findings from a recent audit in one London centre.

    Science.gov (United States)

    Mahon, M; Vickers, D; McCarthy, K; Barker, R; Merritt, R; Szagun, G; Mann, W; Rajput, K

    2011-05-01

    A 5-year retrospective audit of demographic, audiological, and other records of 147 children implanted at one London centre was conducted. The aim was to detail the number of children implanted, with a specific focus on children from families with English as an additional language (EAL), and to compare these children with children from monolingual English-speaking families on a variety of characteristics known to affect paediatric cochlear implant outcomes. In all, 28% of children were from families where English is an additional language, with 15 different languages recorded. There were no differences between EAL and English-speaking children with respect to age of implantation; bilateral versus unilateral implants or hearing levels in better ear. There were differences between these groups in aetiology, in the occurrence of additional needs, and in educational placements. Information about speech and language outcomes was difficult to gather. Conclusions indicate the need for more detailed record-keeping especially about children's home languages for purposes of planning intervention and for the inclusion of children with EAL in future studies.

  2. Screening for latent TB, HIV, and hepatitis B/C in new migrants in a high prevalence area of London, UK: a cross-sectional study.

    Science.gov (United States)

    Hargreaves, Sally; Seedat, Farah; Car, Josip; Escombe, Rod; Hasan, Samia; Eliahoo, Joseph; Friedland, Jon S

    2014-12-03

    Rising rates of infectious diseases in international migrants has reignited the debate around screening. There have been calls to strengthen primary-care-based programmes, focusing on latent TB. We did a cross-sectional study of new migrants to test an innovative one-stop blood test approach to detect multiple infections at one appointment (HIV, latent tuberculosis, and hepatitis B/C) on registration with a General Practitioner (GP) in primary care. The study was done across two GP practices attached to hospital Accident and Emergency Departments (A&E) in a high migrant area of London for 6 months. Inclusion criteria were foreign-born individuals from a high TB prevalence country (>40 cases per 100,000) who have lived in the UK ≤ 10 years, and were over 18 years of age. All new migrants who attended a New Patient Health Check were screened for eligibility and offered the blood test. We followed routine care pathways for follow-up. There were 1235 new registrations in 6 months. 453 attended their New Patient Health Check, of which 47 (10.4%) were identified as new migrants (age 32.11 years [range 18-72]; 22 different nationalities; time in UK 2.28 years [0-10]). 36 (76.6%) participated in the study. The intervention only increased the prevalence of diagnosed latent TB (18.18% [95% CI 6.98-35.46]; 181.8 cases per 1000). Ultimately 0 (0%) of 6 patients with latent TB went on to complete treatment (3 did not attend referral). No cases of HIV or hepatitis B/C were found. Foreign-born patients were under-represented at these practices in relation to 2011 Census data (Chi-square test -0.111 [95% CI -0.125 to -0.097]; p < 0.001). The one-stop approach was feasible in this context and acceptability was high. However, the number of presenting migrants was surprisingly low, reflecting the barriers to care that this group face on arrival, and none ultimately received treatment. The ongoing UK debate around immigration checks and charging in primary care for new

  3. Peri-operative management of high-risk paediatric adenotonsillectomy patients: A survey of 35 UK tertiary referral centres.

    Science.gov (United States)

    Cheong, Ryan Chin Taw; Bowles, Philippe; Moore, Andrew; Watts, Simon

    2017-05-01

    Peri-operative management of high-risk paediatric patients undergoing adenotonsillectomy for treatment of obstructive sleep apnoea varies between tertiary referral hospitals. 'Day of surgery cancellation' (DoSC) rates of up to 11% have been reported due to pre-booked critical care being unavailable on the day of surgery as a result of competing needs from other hospital departments. We report the results of a survey of peri-operative management in UK tertiary care centres of high-risk paediatric patients undergoing adenotonsillectomy for obstructive sleep apnoea (OSA). An 8-point questionnaire was developed using a cloud-based software platform (www.surveymonkey.com). A web-link to the survey was embedded in a customised e-mail which was sent via secure server to the Clinical Leads for Paediatric Otolaryngology at 35 United Kingdom (UK) Tertiary referral centres. The survey response rate was 60% (n = 21). Almost all (94.1%) of centres considered paediatric critical care facilities to be limited, with 70.6% (n = 12) stating that DoSC often occurred due to unavailable paediatric critical care capacity. There was variation between tertiary referral units in the practice applied for pre-booking critical care beds (our survey identifies 6 variations) (Table 1). The most frequent selection method reported (47.1%) was at the discretion of the booking clinician at the time of listing the patient for surgery. In the context of limited critical care resources, variation in practice and difficulty in accurately predicting which patients will require post-operative critical care beds, a review and consensus on best practice in the peri-operative management of high risk paediatric adenotonsillectomy patients may offer a safe means of reducing cancellations and improving patient care, resource allocation and hospital efficiency. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Percutaneous abscess drainage in the UK: A national survey and single centre study

    Energy Technology Data Exchange (ETDEWEB)

    Buckley, B.T. [Radiology Department, John Radcliffe Hospital, Oxford (United Kingdom)]. E-mail: BrendanB@adhb.govt.nz; Goodwin, M. [Radiology Department, John Radcliffe Hospital, Oxford (United Kingdom); Boardman, P. [Radiology Department, John Radcliffe Hospital, Oxford (United Kingdom); Uberoi, R. [Radiology Department, John Radcliffe Hospital, Oxford (United Kingdom)

    2006-01-15

    AIM: To establish the current practice for management of radiologically placed percutaneous drains for abdominal sepsis in the UK and prospectively study the management of radiologically placed drains at our institution. METHOD: A questionnaire on the management of radiologically placed drains was sent to all radiology departments on a Royal College of Radiologists database. We prospectively followed all drains placed by our radiology department for drainage of abdominal collections, over a 7-month period. RESULTS: A total of 210 questionnaires were sent for the national survey, of these 117 were returned (55.7%). The majority of departments (70.5%) reported that after drain insertion the clinical team took over daily management. Just over 5% of departments either formally managed the drain or obtained final outcome data. From October 2003 to April 2004 we followed 63 consecutive drains placed in 45 patients, for abdominal sepsis. Thirty-nine drains (61.9%) were curative and 17 (26.9%) drains failed. Three drains (4.8%) were placed for palliation, and four drains (6.4%) were placed in order to temporise prior to surgery. Forty-three (68.3%) drains had a successful primary outcome: success after secondary percutaneous abscess drainage (PAD) improved to 46 (73.0%) drains. Two (3%) major complications occurred. CONCLUSIONS: The current approach in the UK to management of radiologically placed drains differs significantly from that practised in the USA. The most common type of support offered by radiology departments in the UK is of informal advice and follow-up, with the clinical team managing the patient's drain. Observations in our hospital highlighted problems relating to drain management that may impact on the success of PAD. We suggest that more formal radiological support after PAD would improve communication and potentially improve outcomes.

  5. Personal exposure of street canyon intersection users to PM 2.5, ultrafine particle counts and carbon monoxide in Central London, UK

    Science.gov (United States)

    Kaur, S.; Nieuwenhuijsen, M.; Colvile, R.

    Short-term human exposure to PM 2.5, ultrafine particle counts (particle range: 0.02-1 μm) and carbon monoxide (CO) was investigated at and around a street canyon intersection in Central London, UK. During a four-week field campaign, groups of four volunteers collected samples at three timings (morning, lunch and afternoon), along two different routes (a heavily trafficked route and a backstreet route) via five modes of transport (walking, cycling, bus, car and taxi). PM 2.5 was sampled using high-flow gravimetric personal samplers, ultrafine particle counts were measured using TSI P-TRAKs and Langans were used to measure CO exposure. Three hundred and ninety-four samples were collected—197 PM 2.5, 86 ultrafine particle count and 111 CO. Arithmetic means of PM 2.5 personal exposure were 27.5, 33.5, 34.5, 38.0 and 41.5 μg m -3, ultrafine particle counts were 67 773, 93 968, 101 364, 99 736 and 87 545 pt cm -3 and CO levels were 0.9, 1.1, 0.8, 1.3 and 1.1 ppm for walking, cycling, bus, car and taxi respectively. On the heavily trafficked route, personal exposure was 35.3 μg m -3, 101142 pt cm -3 and 1.3 ppm, and on the backstreet route it was 31.8 μg m -3, 71628 pt cm -3 and 0.6 ppm for PM 2.5, ultrafine particle counts and CO, respectively. Personal exposure levels were high during the morning measurements for all three pollutants (34.6 μg m -3, 106 270 pt cm -3 and 1.5 ppm for PM 2.5, ultrafine particle counts and CO, respectively).There was a moderately strong correlation between personal exposure of ultrafine particle counts and CO ( r=0.7, N=67) but a weaker correlation between PM 2.5 and ultrafine particle counts ( r=0.5, N=83) and a low correlation between PM 2.5 and CO exposure ( r=0.2, N=105). The exposure assessment also revealed that the background and kerbside monitoring stations were not representative of the personal exposure of individuals to PM 2.5 and CO at and around a street canyon intersection.

  6. Factors influencing elementary school children's attitudes toward science before, during, and after a visit to the UK National Space Centre

    Science.gov (United States)

    Jarvis, Tina; Pell, Anthony

    2005-01-01

    This article reports on attitude changes of 300 children, aged 10 or 11 years, from four schools, who visited the UK National Space Centre. Attitudes toward science and space were explored by examining responses to five different attitude scales. These were administered before, immediately after, and 2 months and 4-5 months after a visit to the main exhibition area and Challenger Centre. Observations during the visits and interviews of teachers and a sample of children were carried out. Before the visit girls were more anxious than boys. Immediately afterward, children showed more interest in space and a moderate increase in their views about the value of science in society. Nearly 20% of the pupils showed an increased desire to become scientists in the future. These children also showed a positive advantage over the other children with regard to science enthusiasm and space interest. Two months later, they continued to be more positive about being future scientists but only the girls' scores were still significantly raised. Most children found the Challenger experience positive but had more problems with the exhibition area. Teachers' preparation and support during the visit as well as their personal interest had a significant long-term effect on children's attitudes.

  7. Early virological response to HIV treatment: can we predict who is likely to experience subsequent treatment failure? Results from an observational cohort study, London, UK.

    Science.gov (United States)

    Brima, Nataliya; Lampe, Fiona C; Copas, Andrew; Gilson, Richard; Williams, Ian; Johnson, Margaret A; Phillips, Andrew N; Smith, Colette J

    2017-08-30

    For people living with HIV, the first antiretroviral treatment (ART) regimen offers the best chance for a good virological response. Early identification of those unlikely to respond to first-line ART could enable timely intervention and increase chances of a good initial treatment response. In this study we assess the extent to which the HIV RNA viral load (VL) at 1 and 3 months is predictive of first-line treatment outcome at 6 months. Methods All previously ART-naive individuals starting ART at two London centres since 2000 with baseline (-180 to 3 days) VL >500 c/mL had a VL measurement between 6 and 12 months after starting ART, and at least one at month 1 (4-60 days) or month 3 (61-120 days) were included. Lack of treatment response was defined as (i) VL >200 copies/mL at 6 months or (ii) VL >200 copies/mL at 6 months or simultaneous switch in drugs from at least two different drug classes before 6 months. The association with VL measurements at 1 and 3 months post-ART; change from pre-ART in these values; and CD4 count measurements at 1 and 3 months were assessed using logistic regression models. The relative fit of the models was compared using the Akaike information criterion (AIC). A total of 198 out of 3258 individuals (6%) experienced lack of treatment response at 6 months (definition i), increasing to 511 (16%) for definition (ii). Those with a 1-month (day 4-60 window) VL of 100,000 copies/ml had a 4%, 8%, 23% and 24% chance, respectively, of subsequently experiencing treatment non-response at 6 months (definition (i)). When considering the 3-month (day 61-120 window) VL, the chances of subsequently experiencing treatment non-response were, respectively, 3%, 25%, 67% and 75%. Results were similar for definition (ii). Whilst 3-month VL provides good discrimination between low and high risk of treatment failure, 1-month VL does not. Presence of a VL >10,000 copies/ml after 3 months of ART is a cutoff above which individuals are at a

  8. UK National Data Centre archive of seismic recordings of (presumed) underground nuclear tests 1964-1996

    Science.gov (United States)

    Young, John; Peacock, Sheila

    2016-04-01

    The year 1996 has particular significance for forensic seismologists. This was the year when the Comprehensive Test Ban Treaty (CTBT) was signed in September at the United Nations, setting an international norm against nuclear testing. Blacknest, as a long time seismic centre for research into detecting and identifying underground explosions using seismology, provided significant technical advice during the CTBT negotiations. Since 1962 seismic recordings of both presumed nuclear explosions and earthquakes from the four seismometer arrays Eskdalemuir, Scotland (EKA), Yellowknife, Canada (YKA), Gauribidanur, India (GBA), and Warramunga, Australia (WRA) have been copied, digitised, and saved. There was a possibility this archive would be lost. It was decided to process the records and catalogue them for distribution to other groups and institutions. This work continues at Blacknest but the archive is no longer under threat. In addition much of the archive of analogue tape recordings has been re-digitised with modern equipment, allowing sampling rates of 100 rather than 20 Hz.

  9. Assessing Quality Outcome Measures in Children with Coeliac Disease—Experience from Two UK Centres

    Directory of Open Access Journals (Sweden)

    Alexander Ross

    2013-11-01

    Full Text Available Improved diagnosis of coeliac disease has increased incidence and therefore burden on the health care system. There are no quality outcome measures (QOM in use nationally to assess hospital management of this condition. This study applied QOM devised by the East of England paediatric gastroenterology network to 99 patients reviewed at two tertiary hospitals in the Network, to assess the quality of care provided by nurse led and doctor led care models. The average performance across all QOM was 96.2% at Addenbrooke’s Hospital (AH, and 98.7% at Norfolk and Norwich Hospital (NNUH, whilst 95% (n = 18 of QOM were met. Patient satisfaction was high at both sites (uptake of questionnaire 53 of 99 patients in the study. The study showed a comparably high level of care delivered by both a nurse and doctor led service. Our quality assessment tools could be applied in the future by other centres to measure standards of care.

  10. Looking Forward, Looking Back: Future Challenges for Narrative Research An event commemorating the tenth anniversary of the Centre for Narrative Research, University of East London

    Directory of Open Access Journals (Sweden)

    Molly Andrews

    2011-01-01

    Full Text Available The Centre for Narrative Research was founded at the turn of the millenium. To commemorate its tenth anniversary, we organised an event which took place on November 10, 2010, at the Marx Memorial Library in London. The day had a very flexible format. We began with a few opening words from the three co-directors (Molly Andrews, Corinne Squire, and Maria Tamboukou and the Research Fellow (Cigdem Esin of CNR. This was followed by contributions from six leading narrative scholars (Jens Brockmeier, Michael Erben, Mark Freeman, Margareta Hydén, Margaretta Jolly, and Olivia Sagan to which Alexandra Georgakopoulou and Matti Hyvärinen then responded. Following lunch, the sixty participants were broken up into smaller groups, where they discussed issues raised in the morning session. The day concluded with a final discussion piece offered by Mike Rustin. The six presenters were faced with a formidable challenge. We invited them to write pieces of approximately 500 words on "the promise and challenges for future narrative research, including critiques of and hopes for our own scholarship." These were prepared in advance of the event, and sent to the discussants, who were asked not only to comment upon the set of issues raised, but also to provide a framework for looking at the problems as a whole set. Not only did the contributors and discussants come from a range of different backgrounds and geographical locations, but the range of intellectual interests represented by those who attended the day was very marked: poets, writers of fiction, policy makers, psychoanalysts, sociologists, psychologists, political scientists, social workers, and others. Perhaps the most outstanding feature of the day was the conversations which happened across boundaries, characterised by both a search for common ground as well as a recognition of the different intellectual standpoints represented by the people there. What follows are written versions of the prepared, spoken

  11. Mortality in systemic sclerosis-a single centre study from the UK.

    Science.gov (United States)

    Strickland, Gemma; Pauling, John; Cavill, Charlotte; Shaddick, Gavin; McHugh, Neil

    2013-10-01

    This study aims to determine the cause and predictors of mortality in a cohort of patients with systemic sclerosis (SSc) and assess whether the mortality rate differs significantly from the general population. Patients enrolled onto the Royal National Hospital for Rheumatic Diseases Connective Tissue Disease database between 1999 and 2010 were included in this study. The NHS Strategic Tracing Service and UK Registry of Births, Marriages and Deaths were used to establish date and cause of deaths. A retrospective case note review collected information on clinical phenotype and serology. A standardised mortality ratio (SMR) was calculated and survival was determined using Kaplan-Meier estimates. Univariate and multivariate predictors of survival were assessed using proportional hazards regression modelling. Amongst this cohort of 204 patients (25 males, 40 diffuse SSc), the mean age at diagnosis was 51.6 years (SD13.7) and the mean duration of follow-up was 12.5 years (SD 8.8 years). In the deceased group (53 patients), the mean age of death was 72.0 years (SD 12.3 years). The mean disease duration at death was 14.2 years (SD 8.5 years). The overall SMR was 1.34 (95 % confidence interval (CI) 1.00-1.75). The SMR was higher in males (1.54 [95 % CI 0.67-3.04] vs. 1.30 [95 % CI 0.95-1.74]). The leading causes of death in this cohort were infection, respiratory disease and malignancy. The most common cause of SSc-related mortality was pulmonary complications. Factors adversely affecting survival were older age at diagnosis, male gender, interstitial lung disease (ILD) and anti-RNA polymerase III antibody. The mortality rate of our cohort, who had predominantly limited disease, was higher than that of the general population; although not as high as reported in previous retrospective studies.

  12. Percutaneous nephrostomy insertion: outcome data from a prospective multi-operator study at a UK training centre

    Energy Technology Data Exchange (ETDEWEB)

    Wah, T.M.; Weston, M.J.; Irving, H.C. E-mail: henry.irving@leedsth.nhs.uk

    2004-03-01

    AIM: To determine the success and complication rates of percutaneous nephrostomies (PCNs) performed at a UK training centre over a one-year period by different groups of operators. MATERIALS AND METHODS: During 2002, a total of 276 PCNs were performed in 190 patients by operators of varying experience. We employed two different techniques: (1) a 'Seldinger' technique (ultrasound-guided puncture with a 19 G sheathed needle followed by guide-wire insertion and track dilatation to accommodate 8-12 F nephrostomy catheters), with or without fluoroscopic guidance, and (2) an ultrasound-guided 'one-stab' technique using a 6 F Bonanno catheter. Selection of technique was according to configuration of the collecting system and whether the procedure was performed out of hours. RESULTS: There were 218 procedures using the Seldinger technique and 62 using the one-stab technique. The Seldinger technique and one-stab technique were compared: primary technical success rate was 98 versus 93%, the major complication rate was 4.1 versus 3.2%, the minor complication rate was 5 versus 13%, and tube complications, such as drainage catheter dislodgement and blockage, were 29.5 versus 17.7%, respectively. The 30-day mortality was 4.3%, none of which were procedure related. CONCLUSION: Based on data from the USA, proposed targets for primary technical success rates are 88-99%, major complications 4-8%, and minor complications 3-15%, and the results were within these target ranges. The ultrasound-guided one-stab technique is a quick and safe procedure in selected cases, and we recommend this method for temporary urinary diversion in cases with moderate to severe degrees of pelvicalyceal system dilatation. These data may help to form a baseline for outcome targets in the UK.

  13. Enteral feeding in head and neck cancer patients at a UK cancer centre.

    Science.gov (United States)

    Sheth, C H; Sharp, S; Walters, E R

    2013-10-01

    Patients undergoing radiotherapy or chemoradiotherapy treatment for head and neck cancer have an increased risk of malnutrition, and may require enteral feeding via nasogastric or gastrostomy tube. The aim of this audit was to examine current enteral feeding practice, mortality, morbidity and 6-month outcome data of head and neck cancer patients receiving radical (chemo)radiotherapy at a regional cancer centre and to compare the results with a regional head and neck cancer gastrostomy audit. A 2-year audit was conducted (2006-2008). Inclusion criteria were all adult patients diagnosed with squamous cell carcinoma of the head and neck, receiving radical radiotherapy or chemoradiotherapy treatment. The first-year data were collected retrospectively, and the second-year data were collected prospectively. Data were collected on all patients requiring enteral feeding with 6-month outcome data relating to route of nutrition. Approximately 14% (n = 32/223) of patients were admitted for nasogastric feeding as a result of inadequate oral alimentation. On admission, 94% were at risk of refeeding syndrome, taking a mean (SD) of 11 (4.9) days to reach full nutritional requirements. Mean (SD) length of hospital stay was 13 (5.1) days. No major complications from nasogastric tube insertion were found. The mean (SD) length of nasogastric feeding was 72 (20.1) days with 89.6% managing full nutritional requirements orally at 6 months. Patients requiring enteral feeding during treatment were fed via a nasogastric tube, rather than via a prophylactic gastrostomy tube. Compared with the regional gastrostomy audit results, our patients had a lower clinical risk/complication rate, with a greater proportion tolerating full oral intake at 6 months. Therefore, nasogastric feeding, rather than prophylactic gastrostomy tube feeding, could be a more appropriate method of enteral feeding in this patient group. © 2013 University Hospital Southampton Journal of Human Nutrition and Dietetics

  14. Pregnancy outcomes in sickle cell disease: a retrospective cohort study from two tertiary centres in the UK.

    Science.gov (United States)

    Chase, A R; Sohal, M; Howard, J; Laher, R; McCarthy, A; Layton, D M; Oteng-Ntim, E

    2010-09-01

    The objective of this retrospective cohort study from two tertiary centres in the UK was to describe the pregnancy outcomes of women with sickle cell disease (SCD) who booked at these centres between 2004 and 2008, and to compare this with historical data. The study population comprised 122 singleton pregnancies in women with SCD: homozygous sickle cell disease 64, sickle cell haemoglobin C disease 45, sickle b plus thalassaemia 11, sickle cell haemoglobin E disease 1 and sickle cell delta disease 1 from 2004 to 2008 managed in the joint haematology/obstetric antenatal clinics in two tertiary teaching hospitals. The main outcome measures were the frequency of sickle cell crises and obstetric complications. Age and gestation at booking were 18-43 years (mean 29.7) and 9-36 weeks gestation (mean 17.3), respectively. Complications of SCD occurred in 25% of pregnancies. Fifty-four percent of women had induction of labour and 39% were delivered by emergency caesarean section. Thirty-three percent had a postpartum haemorrhage. Nineteen percent of women delivered before 37 completed weeks. Birth weight below 2500 g occurred in 20% of singleton pregnancies. Three neonates developed transient complications related to maternal opiate exposure postnatally. Three intrauterine deaths occurred at 24, 29 and 34 weeks. Two of these had congenital defects, and the other severe intrauterine growth restriction. No maternal deaths occurred. Successful pregnancy outcomes can be achieved in SCD. There has been an improvement in fetal and maternal morbidity and mortality compared with historical data. Pregnancy in women with SCD remains high risk. Early access to antenatal care and to expertise in SCD is essential. A matched control population from the same time period and prospective data collection is needed to address confounders such as ethnicity and deprivation.

  15. Nutrition Labeling and Portion Size Information on Children's Menus in Fast-Food and Table-Service Chain Restaurants in London, UK

    Science.gov (United States)

    Reeves, Sue; Wake, Yvonne; Zick, Andrea

    2011-01-01

    Objective: To investigate meals, price, nutritional content, and nutrition and portion size information available on children's menus in fast-food and table-service chain restaurants in London, since the United Kingdom does not currently require such information but may be initiating a voluntary guideline. Methods: Children's menus were assessed…

  16. London 2012 - Medal Projection - Medaillenvorausberechnung

    OpenAIRE

    2012-01-01

    We project the medal number and medal ranking for the Olympic Games in London in 2012. The largest relative increase is predicted for Brazil (80% more medals) and the UK (+28%).UK will conti-nue to rank 4th. The largest decreases in medal numbers are predicted for Australia (-13%, but remains in 5th place) and the USA (-13%, remains No. 1). Germany should retain a rank of 6th and will win 38 medals (compared to 41 in 2008).

  17. A multi-centre study of interactional style in nurse specialist- and physician-led Rheumatology clinics in the UK.

    Science.gov (United States)

    Vinall-Collier, Karen; Madill, Anna; Firth, Jill

    2016-07-01

    Nurse-led care is well established in Rheumatology in the UK and provides follow-up care to people with inflammatory arthritis including treatment, monitoring, patient education and psychosocial support. The aim of this study is to compare and contrast interactional style with patients in physician-led and nurse-led Rheumatology clinics. A multi-centre mixed methods approach was adopted. Nine UK Rheumatology out-patient clinics were observed and audio-recorded May 2009-April 2010. Eighteen practitioners agreed to participate in clinic audio-recordings, researcher observations, and note-taking. Of 9 nurse specialists, 8 were female and 5 of 9 physicians were female. Eight practitioners in each group took part in audio-recorded post-clinic interviews. All patients on the clinic list for those practitioners were invited to participate and 107 were consented and observed. In the nurse specialist cohort 46% were female; 71% had a diagnosis of Rheumatoid Arthritis (RA). The physician cohort comprised 31% female; 40% with RA and 16% unconfirmed diagnosis. Nineteen (18%) of the patients observed were approached for an audio-recorded telephone interview and 15 participated (4 male, 11 female). Forty-four nurse specialist and 63 physician consultations with patients were recorded. Roter's Interactional Analysis System (RIAS) was used to code this data. Thirty-one semi-structured interviews were conducted (16 practitioner, 15 patients) within 24h of observed consultations and were analyzed using thematic analysis. RIAS results illuminated differences between practitioners that can be classified as 'socio-emotional' versus 'task-focussed'. Specifically, nurse specialists and their patients engaged significantly more in the socio-emotional activity of 'building a relationship'. Across practitioners, the greatest proportion of 'patient initiations' were in 'giving medical information' and reflected what patients wanted the practitioner to know rather than giving insight into

  18. Partnerships in Pharma--An Economist Intelligence Unit Seminar--Building Innovation into Alliances and Business Models. 1 October 2010, London, UK.

    Science.gov (United States)

    Kibble, Alexandra

    2010-12-01

    The Partnerships in Pharma seminar, held in London, included topics related to building innovation into alliances and business models within the pharmaceutical industry. This conference report highlights selected presentations on strategies for successful partnering, partnering alongside an evolving CRO industry, considering the pharma value chain, and partnerships between industry and academia. Approaches used by Ipsen, Merck Serono, Pfizer and ViiV Healthcare are also described.

  19. The 8th International Conference on Counter-current Chromatography held at Brunel University, London, UK, July 23-25, 2014.

    Science.gov (United States)

    Ignatova, Svetlana; Sutherland, Ian

    2015-12-18

    The 8th International Conference on Counter-current Chromatography (CCC2014) was held at Brunel University London from July 23rd to 25th, 2014. It has been 14 years since Brunel hosted the first International Conference on CCC (CCC2000) at the beginning of the millennium and therefore, it was a good opportunity to review the progress of this emerging technology and particularly the impact it is having with industry today.

  20. The UK Neovascular AMD Database Report 3: inter-centre variation in visual acuity outcomes and establishing real-world measures of care.

    Science.gov (United States)

    Liew, G; Lee, A Y; Zarranz-Ventura, J; Stratton, I; Bunce, C; Chakravarthy, U; Lee, C S; Keane, P A; Sim, D A; Akerele, T; McKibbin, M; Downey, L; Natha, S; Bailey, C; Khan, R; Antcliff, R; Armstrong, S; Varma, A; Kumar, V; Tsaloumas, M; Mandal, K; Egan, C; Johnston, R L; Tufail, A

    2016-11-01

    PurposeInternational variations in visual acuity (VA) outcomes of eyes treated for neovascular age-related macular degeneration (nAMD) are well-documented, but intra-country inter-centre regional variations are not known. These data are important for national quality outcome indicators. We aimed to determine intra-country and inter-centre regional variations in outcomes for treatment of nAMD.Patients and methodsProspective multicentre national database study of 13 UK centres that treated patients according to a set protocol (three loading doses, followed by Pro-Re-Nata retreatment). A total of 5811 treatment naive eyes of 5205 patients received a total of 36 206 ranibizumab injections over 12 months.ResultsMean starting VA between centres varied from 48.9 to 59.9 ETDRS letters. Mean inter-centre VA change from baseline to 12 months varied from +6.9 letters to -0.6 letters (mean of +2.5 letters). The proportion of eyes achieving VA of 70 letters or more varied between 21.9 and 48.7% at 12 months. Median number of injections (visits) at each centre varied from 5 to 8 (9 to 12), with an overall median of 6 (11). Age, starting VA, number of injections, and visits, but not gender were significantly associated with variation in these VA outcomes (Peven after adjusting for these factors.ConclusionThere are modest differences in VA outcomes between centres in the UK. These differences are influenced, but not completely explained, by factors such as patient age, starting VA, number of injections, and visits. These data provide an indication of the VA outcomes that are achievable in real-world settings.

  1. Mid-Pliocene climate modelled using the UK Hadley Centre Model: PlioMIP Experiments 1 and 2

    Directory of Open Access Journals (Sweden)

    F. J. Bragg

    2012-09-01

    Full Text Available The Pliocene Model Intercomparison Project (PlioMIP is a sub-project of the Paleoclimate Modelling Intercomparison Project (PMIP whose objective is to compare predictions of the mid-Pliocene climate from the widest possible range of general circulation models. The mid-Pliocene (3.3–3.0 Ma is the most recent sustained period of greater warmth and atmospheric carbon dioxide concentration than the pre-industrial times and as such has potential to inform predictions of our warming climate in the coming century. This paper describes the UK contribution to PlioMIP using the Hadley Centre Model both in atmosphere-only mode (HadAM3, PlioMIP Experiment 1 and atmosphere-ocean coupled mode (HadCM3, PlioMIP Experiment 2. The coupled model predicts a greater overall warming (3.3 °C relative to the control than the atmosphere-only (2.5 °C. The Northern Hemisphere latitudinal temperature gradient is greater in the coupled model with a warmer Equator and colder Arctic than the atmosphere-only model, which is constrained by sea surface temperatures from Pliocene proxy reconstructions. The atmosphere-only model predicts a reduction in equatorial precipitation and south Asian monsoon intensity, whereas the coupled model shows an increase in the intensity of these systems. We present sensitivity studies using alternative boundary conditions for both the Pliocene and the control simulations, indicating the sensitivity of the mid-Pliocene warming to uncertainties in both pre-industrial and mid-Pliocene climate.

  2. Fritz London

    Science.gov (United States)

    Gavroglu, Kostas

    2005-11-01

    Preface; Acknowledgements; Part I. From Philosophy to Physics: The years that left nothing unaffected; 1. The appeal of ideas; 2. Goëthe as a scientist; 3. How absolute is our knowledge?; 4. How do we come to know things?; 5. London's teachers in philosophy; 6. Husserl's teachings; 7. Expectations of things to come; 8. The thesis in philosophy; 9. Tolman's principle of similitude; 10. The necessary clarifications; 11. Work on quantum theory; 12. Transformation theory; 13. Unsuccessful attempts at unification; Part II. The Years in Berlin and the Beginnings of Quantum Chemistry: The mysterious bond; 14. London in Zürich; 15. Binding forces; 16. The Pauli principle; 17. Reactions to the Heitler-London paper; 18. Polyelectronic molecules and the application of group theory to problems of chemical valence; 19. Chemists as physicists?; 20. London's first contacts in Berlin; 21. Marriage; 22. Job offers; 23. Intermolecular forces; 24. The book which could not be written; 25. Leningrad and Rome; 26. Difficulties with group theory; 27. Linus Pauling's resonance structures; 28. Robert Mulliken's molecular orbitals; Part III. Oxford and Superconductivity: The rise of the Nazis; 29. Going to Oxford; 30. Lindemann, Simon and Heinz London; 31. Electricity in the very cold; 32. The end of old certainties; 33. The thermodynamic treatment; 34. The theory of Fritz and Heinz London; 35. Initial reactions by von Laue; 36. The discussion at the Royal Society; 37. Termination of the ICI fellowship; Part IV. Paris and Superfluidity: The Front Populaire; 38. The article in Nature 1937 and 'Nouvelle Conception'; 39. Laue again; 40. The structure of solid helium; 41. The peculiar properties of helium; 42. Bose-Einstein condensation; 43. The note in Nature; 44. The two-fluid model; 45. The trip to Jerusalem; 46. Leaving again; 47. The observer in quantum mechanics; Part V. United States and the Typing up of Loose Ends: Duke University, North Carolina; 48. The Soviet Union, Kapitza and

  3. 17 April 2013 - UK Queen Mary University London Principal S. Gaskell in the ATLAS control room at LHC Point 1, LHC tunnel and ATLAS experimental cavern with Collaboration Spokesperson D. Charlton and signing the guest book with CERN Director for Accelerators and Technology S. Myers.

    CERN Multimedia

    Maximilien Brice

    2013-01-01

    17 April 2013 - UK Queen Mary University London Principal S. Gaskell in the ATLAS control room at LHC Point 1, LHC tunnel and ATLAS experimental cavern with Collaboration Spokesperson D. Charlton and signing the guest book with CERN Director for Accelerators and Technology S. Myers.

  4. What factors influence UK medical students’ choice of foundation school?

    OpenAIRE

    Miah S; Pang KH; Rebello W; Rubakumar Z; Fung V; Venugopal S.; Begum H

    2017-01-01

    Saiful Miah,1,2 Karl H Pang,3 Wayne Rebello,4 Zoe Rubakumar,4 Victoria Fung,5 Suresh Venugopal,6 Hena Begum4 1Division of Surgery and Interventional science, University College London, London, UK; 2Department of Urology, Charing Cross Hospital Imperial College Healthcare NHS Trust, London, UK; 3Academic Urology Unit, University of Sheffield, Sheffield, UK; 4Medical School, University of Sheffield, Sheffield, UK; 5Department of Plastic Surgery, Royal Hallamshire Hospital, Sheffield, UK; 6Depar...

  5. Rail environmental impact: energy consumption and noise pollution assessment of different transport modes connecting Big Ben (London, UK and Eiffel Tower (Paris, FR

    Directory of Open Access Journals (Sweden)

    Roberto PALACIN

    2014-10-01

    Full Text Available This paper is set within the framework of the RailNewcastle Summer School program 2014 run by Newcastle University. It attempts to explore the sustainability credentials of railways when compared with other transport modes connecting central London with central Paris, two of Europe’s largest metropolis. Specifically, the study compares the energy consumption and noise pollution of a rail-only travel option with two other alternatives using a combination of public transport modes. The analysis includes defining the regulatory framework, sourcing and aggregating energy consumption from a number of references as well as creating noise maps for key nodes using validated tools available. The results suggest that the rail-only option has the best performance of the three options in terms of energy consumption while a bus-coach-metro combination seems to have lower noise levels than the rest. Assumptions due to lack of meaningful data made in the calculation of underground rail services are thought to have influence on the lower than expected performance of rails systems in terms of noise. The authors conclude that considering the combined outcomes of both assessments, the rail-only option is the preferred choice from a sustainability credentials perspective.

  6. Preventing work-related stress among staff working in children's cancer Principal Treatment Centres in the UK: a brief survey of staff support systems and practices.

    Science.gov (United States)

    Beresford, B; Gibson, F; Bayliss, J; Mukherjee, S

    2016-07-04

    Growing evidence of the association between health professionals' well-being and patient and organisational outcomes points to the need for effective staff support. This paper reports a brief survey of the UK's children's cancer Principal Treatment Centres (PTCs) regarding staff support systems and practices. A short on-line questionnaire, administered in 2012-2013, collected information about the availability of staff support interventions which seek to prevent work-related stress among different members of the multi-disciplinary team (MDT). It was completed by a member of staff with, where required, assistance from colleagues. All PTCs (n = 19) participated. Debriefs following a patient death was the most frequently reported staff support practice. Support groups were infrequently mentioned. There was wide variability between PTCs, and between professional groups, regarding the number and type of interventions available. Doctors appear to be least likely to have access to support. A few Centres routinely addressed work-related stress in wider staff management strategies. Two Centres had developed a bespoke intervention. Very few Centres were reported to actively raise awareness of support available from their hospital's Occupational Health department. A minority of PTCs had expert input regarding staff support from clinical psychology/liaison psychiatry.

  7. Adverse outcomes of pregnancy in HIV-positive women in the era of HAART: a perspective from an outer London centre in the UK

    Directory of Open Access Journals (Sweden)

    P Thayaparan

    2012-11-01

    Full Text Available Background: Increasing number of women with HIV are choosing to become pregnant as there is dramatic reduction in the risk of vertical transmission. However, management of HIV in pregnancy still poses a variety of challenges and adverse pregnancy outcomes are still common. We aimed to explore the factors associated with adverse outcomes of pregnancy in our HIV cohort. Methods: It is a retrospective case note review of all the women attended our unit and had HIV care from 2008–2011. A total of 87 women were followed up. Three women had two pregnancies during the study period. Data collected from Genitourinary Medicine and maternity records were analysed using SPSS program. Results: Mean age was 34 yrs ranging from 20–43 yrs. Majority (91% were of African origin; 67% had HIV subtype C; 26% resistant to one or more class of HIV drugs; 55% had a nadir CD4 fewer than 350; 44% diagnosed at an antenatal setting and 62% were planned pregnancies. Prior to the current pregnancy, these women had 121 children: 5% of the children have HIV and 33% not tested for HIV. Of the partners, 38% have HIV and 73% were aware of their partner's HIV status. None of the children born during the study period were infected with HIV; mean birth weight was 2789 g; there were 3 sets of twins; one still birth and one child died soon after birth. Around 46% were on anti-retroviral therapy (ART during conception, 6% had miscarriages and 16% had emergency caesarean sections. At delivery, viral load was detectable in 23%, mainly due to poor adherence (11% and late presentation (9%. 38% of the women experienced an obstetric complication, premature labour 9%; premature rupture of membranes and gestational diabetes both accounted to 4% whilst 3% had post-partum haemorrhage. On ART during conception and late HIV diagnosis that is nadir CD4, less than 350 cells were significantly associated (P<0.05 with having a foetal complication such as prematurity 8%, low birth weight 7% or having a foetal abnormality 2.3%. There was no significant association between 1st and 2nd trimester ART exposure and adverse pregnancy outcomes such as prematurity, low birth weight or foetal abnormality. Conclusion: Late diagnosis of HIV and ART during conception is significantly associated with adverse outcomes of pregnancy. Widespread HIV testing is essential and has to be extended to non-traditional settings. In addition, more studies are needed on ART exposure and adverse pregnancy outcomes.

  8. Environmental health impacts: occurrence, exposure and significance, Lancaster University, UK, 9-10 September 2003.

    Science.gov (United States)

    Martin, Francis L; Semple, Kirk T

    2004-09-01

    Speakers: John Ashby (Syngenta CTL, UK), Peter A. Behnisch (Eurofins GfA, Germany), Paul L. Carmichael (Unilever Colworth, UK), Curtis C.Harris (National Cancer Institute, USA), Kevin C. Jones (Lancaster University, UK), Andreas Kortenkamp (School of Pharmacy, London, UK), Caroline J. Langdon (Reading University, UK), Anthony M. Lynch (GlaxoSmithKline, UK), Francis L. Martin (Lancaster University, UK), Trevor J. McMillan (Lancaster University, UK), David H. Phillips (Institute of Cancer Research, UK), Huw J. Ricketts (University of Cardiff, UK), Michael N. Routledge (University of Leeds, UK), J. Thomas Sanderson (Utrecht University, The Netherlands) and Kirk T. Semple (Lancaster University, UK) The effects of many environmental exposures to either single contaminants or to mixtures still remain to be properly assessed in ecotoxicological and human toxicological settings. Such assessments need to be carried out using relevant biological assays. On a mechanistic basis, future studies need to be able to extrapolate exposure to disease risk. It is envisaged that such an approach would lead to the development of appropriate strategies to either reduce exposures or to initiate preventative measures in susceptible individuals or populations. To mark the opening of a new Institute, the Lancaster Environmental Centre, an environmental health workshop was held over 2 days (9-10 September 2003) at Lancaster University, UK. The fate, behaviour and movement of chemicals in the environment, together with environmental exposures and human health, biomarkers of such exposures, hormone-like compounds and appropriate genetic toxicology methodologies, were discussed.

  9. Facilitating and Nurturing Creativity in Pre-Vocational Dancers: Findings from the UK Centres for Advanced Training

    Science.gov (United States)

    Watson, Debbie E.; Nordin-Bates, Sanna M.; Chappell, Kerry A.

    2012-01-01

    This is a case study investigation into creativity involving young dancers and faculty members on the UK government-funded pre-vocational contemporary dance training programme. Qualitative research techniques were used to gather and interpret data on how individuals nurtured and viewed creativity at an individual level, as well as how the…

  10. Facilitating and Nurturing Creativity in Pre-Vocational Dancers: Findings from the UK Centres for Advanced Training

    Science.gov (United States)

    Watson, Debbie E.; Nordin-Bates, Sanna M.; Chappell, Kerry A.

    2012-01-01

    This is a case study investigation into creativity involving young dancers and faculty members on the UK government-funded pre-vocational contemporary dance training programme. Qualitative research techniques were used to gather and interpret data on how individuals nurtured and viewed creativity at an individual level, as well as how the…

  11. Special issue of selected papers from the second UK-Japan bilateral Workshop and First ERCOFTAC Workshop on Turbulent Flows Generated/Designed in Multiscale/Fractal Ways, London, March 2012

    Science.gov (United States)

    Laizet, Sylvain; Sakai, Yasuhiko; Christos Vassilicos, J.

    2013-12-01

    This special issue of Fluid Dynamics Research includes nine papers which are based on nine of the presentations at the Second UK-Japan bilateral Workshop and First ERCOFTAC Workshop on 'Turbulent flows generated/designed in multiscale/fractal ways: fundamentals and applications' held from 26 to 27 March 2012 at Imperial College London, UK. The research area of fractal-generated turbulent flows started with a chapter published in 2001 in one of the conference proceedings which came out of the 1999 Isaac Newton Institute 6 month Programme on Turbulence in Cambridge (UK). However, the first results which formed the basis of much of the work reported in this special issue started appearing from 2007 onwards and progress since then could perhaps be described as not insignificant. Research in this area has resulted in the following six notable advances: (a) the definition of two new length-scales characterizing grid-generated turbulence; (b) enhanced and energy-efficient stirring and scalar transfer by fractal grid and fractal openings/flanges with applications, in particular, to improved turbulence generation for combustion; (c) the non-equilibrium turbulent dissipation law; (d) non-equilibrium axisymmetric wake laws; (e) insights into the dependence of drag forces and vortex shedding on the fractal geometry of fractal objects and simulation methods for the calculation of drag of fractal trees; and (f) the invention and successful proof of concept of fractal spoilers and fractal fences. The present special issue contains papers directly related to these advances and can be seen as a reflection of the current research in the field of fractal-generated turbulent flows and their differences and commonalities with other turbulent flows. The financial support from the Japan Society for the Promotion of Science has been decisive for the organization and success of this workshop. We are also grateful to ERCOFTAC who put in place the EU-wide Special Interest Group on multiscale

  12. UK Renal Registry 18th Annual Report: Chapter 3 Demographic and Biochemistry Profile of Kidney Transplant Recipients in the UK in 2014: National and Centre-specific Analyses.

    Science.gov (United States)

    Pruthi, Rishi; Casula, Anna; MacPhee, Iain

    2016-01-01

    There was a 2% fall in overall renal transplant numbers in 2014, with a significant fall in kidney donation from donors after circulatory death (10%). In 2014, death-censored renal transplant failure rates in prevalent patients were similar to previous years at 2.4% per annum. Transplant patient death rates remained stable at 2.3 per 100 patient years. The median age of incident and prevalent renal transplant patients in the UK was 50.6 and 53.3 years respectively. The median eGFR of prevalent renal transplant recipients was 52.5 ml/min/1.73 m2. The median eGFR of patients one year after transplantation was 57.4 ml/min/1.73 m2 post live transplant, 53.6 ml/min/1.73 m2 post brainstem death transplant and 50.1 ml/min/1.73 m2 post circulatory death transplant. In 2014, 13% of prevalent transplant patients had eGFR ,30 ml/min/1.73 m2. The median decline in eGFR slope beyond the first year after transplantation was −0.48 ml/min/1.73 m2/year.In 2014, malignancy (26%) and infection (24%) remained the commonest causes of death in patients with a functioning renal transplant.

  13. Working at the weekend: Supermarket and shopping centre workers in Salford/Manchester (UK) and Porto (Portugal)

    OpenAIRE

    Sofia Alexandra Cruz; Jill Ebrey

    2014-01-01

    This paper firstly discusses the origins and importance of the weekend¿ in the industrial¿ cities of Manchester (UK) and Porto (Portugal). Drawing on previous work specifically focused on this subject, it examines the spatio-temporal shifts evident during the industrial revolution, which produced a more disciplined¿ labour process. Work and leisure were, thereafter, constituted as separate domains, the weekend being a designated leisure time and space. We consider the more recent temporal shi...

  14. London, England

    Science.gov (United States)

    2003-01-01

    For almost 2,000 years, the River Thames has served as the life force of London, capital of the United Kingdom and one of the world's most famous cities. In AD 43 the Romans established the trading settlement of Londinium at a favorable crossing point on the river. The Romans remained until the 5th century, when the city came under Saxon control. The early 17th century saw enormous growth, but the deadly plague of 1664 and 1665 ravaged the population, and in the following year the Great Fire, which burned for four days, destroyed most of the city. A public transportation system and other city services in the early 19th century eased many of the increasing urban problems of the burgeoning capital of the wealthy British Empire. After coping with the devastating effects of bombing during World War II and the gradual dismantling of the empire, London today thrives as a vital modern metropolis. London is one of 100 cities being studied using ASTER data to map and monitor urban use patterns and growth.This image was acquired on October 12, 2001 by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra satellite. With its 14 spectral bands from the visible to the thermal infrared wavelength region, and its high spatial resolution of 15 to 90 meters (about 50 to 300 feet), ASTER images Earth to map and monitor the changing surface of our planet.ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products.The broad spectral coverage and high spectral resolution of ASTER will provide scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring

  15. Impact of telephone consent and potential for eye donation in the UK: the Newcastle Eye Centre study

    Science.gov (United States)

    Ting, D S J; Potts, J; Jones, M; Lawther, T; Armitage, W J; Figueiredo, F C

    2016-01-01

    Aims To examine the impact of telephone consent introduced in 2007 on the eye donation rate and to report the changing trend and potential for improvement in eye donation in Newcastle upon Tyne, UK. Methods Relevant data were retrospectively collected from the local eye retrieval database for two separate years, namely, 2006 (before the introduction of telephone consent) and 2010. All the hospitals within Newcastle were included in the study. Results From 2006 to 2010, there was a 3.5-fold increase in eye donation from 32 (of 2479 deaths) to 111 donors per year (of 2213 deaths) in Newcastle (PNewcastle over the recent years. Introduction of telephone consent and high-quality eye donation service serve as effective measures for increasing eye donation. PMID:26514245

  16. Use of plasma human herpesvirus-8 viral load measurement: evaluation of practice in three UK HIV treatment centres.

    Science.gov (United States)

    Nugent, D B; Webster, D; Mabayoje, D; Chung, E; El Bouzidi, K; O'Sullivan, A; Ainsworth, J; Miller, R F

    2017-02-01

    A retrospective audit of plasma human herpesvirus-8 (HHV-8) viral load testing was performed in three HIV treatment centres over 24 months. Reasons for testing (360 tests) were: symptoms of systemic inflammatory response syndrome (SIRS) (fever, lymphadenopathy and raised inflammatory markers); monitoring in known HHV-8 pathology other than Kaposi sarcoma (KS); investigation of known/suspected KS, and other/no reason. Of patients with multicentric Castleman disease (MCD), 14/16 (88%) had detectable plasma HHV-8, as did 27/45 (60%) with biopsy proven or clinically confirmed KS, and 6/19 (32%) with lymphoma. Neither of the two patients with MCD and no detectable HHV-8 had SIRS symptoms at the time of the test. There was wide variation between centres in the indications prompting HHV-8 testing, with a more conservative approach resulting in a higher proportion of positive results. Measuring plasma HHV-8 in the absence of SIRS symptoms, established HHV-8 disease monitoring, or confirmed/suspected KS is unlikely to yield detectable HHV-8 thus allowing potential cost savings.

  17. Intravenous artesunate versus intravenous quinine in the treatment of severe falciparum malaria: a retrospective evaluation from a UK centre

    Science.gov (United States)

    Eder, Marcus; Farne, Hugo; Cargill, Tamsin; Abbara, Aula; Davidson, Robert N

    2012-01-01

    Introduction Despite evidence from developing world trials that intravenous (IV) artesunate (AS) is superior to IV quinine (Q) in severe falciparum malaria (FM), IV AS remains unlicensed in the UK with national guidelines listing it as an acceptable alternative to IV Q as the drug of choice. We retrospectively evaluate the safety and effectiveness of IV AS in returning travellers with severe FM. Methods We identified adults admitted to the Infectious Diseases unit with severe FM and treated with IV Q (1991–2009) or IV AS (2009–2011). Outcomes included adverse events, mortality, length of stay, admission to intensive care and, where data were available, parasite/fever clearance time and hypoglycaemic events. Results Of 167 patients, 24 received IV AS and 143 IV Q. There was one potential AS-associated adverse event, a case of late onset haemolysis. Median length of stay (LOS) was significantly shorter for AS (3.5 versus 5 days, P = 0.017), even after adjusting for African ethnicity (for LOS ⩾3 days, mhor = 0.33, P = 0.027; crude OR = 0.29, P = 0.013). In the AS group, there were no fatalities (versus five in Q group, NS) and fewer intensive care unit (ICU) admissions (NS). Median parasite clearance was significantly faster in AS (65 versus 85 hours in Q, P = 0.0045) with no hypoglycaemic episodes (versus five in Q). Discussion We found IV AS to be safe and effective, with shorter LOS, faster parasite and fever clearance, no fatalities or hypoglycaemic events, and fewer ICU admissions versus IV Q. This corroborates both developing world trials and smaller European case series (although these lacked comparison groups). As well as obvious benefits for patients, there are potential resource savings. A case of late-onset haemolysis may represent an adverse event, particularly as it has been documented elsewhere, warranting further investigation. Nonetheless, our experience suggests IV AS should be first-line for treating severe FM in the UK

  18. Does exposure to the food environment differ by socioeconomic position? Comparing area-based and person-centred metrics in the Fenland Study, UK.

    Science.gov (United States)

    Maguire, Eva R; Burgoine, Thomas; Penney, Tarra L; Forouhi, Nita G; Monsivais, Pablo

    2017-09-06

    Retail food environments (foodscapes) are a recognised determinant of eating behaviours and may contribute to inequalities in diet. However, findings from studies measuring socioeconomic inequality in the foodscape have been mixed, which may be due to methodological differences. The aim of this cross-sectional study was to compare exposure to the foodscape by socioeconomic position using different measures, to test whether the presence, direction or amplitude of differences was sensitive to the choice of foodscape metric or socioeconomic indicator. A sample of 10,429 adults aged 30-64 years with valid home address data were obtained from the Fenland Study, UK. Of this sample, 7270 participants also had valid work location data. The sample was linked to data on food outlets obtained from local government records. Foodscape metrics included count, density and proximity of takeaway outlets and supermarkets, and the percentage of takeaway outlets relative to all food outlets. Exposure metrics were area-based (lower super output areas), and person-centred (proximity to nearest; Euclidean and Network buffers at 800 m, 1 km, and 1 mile). Person-centred buffers were constructed using home and work locations. Socioeconomic status was measured at the area-level (2010 Index of Multiple Deprivation) and the individual-level (highest educational attainment; equivalised household income). Participants were classified into socioeconomic groups and average exposures estimated. Results were analysed using the statistical and percent differences between the highest and lowest socioeconomic groups. In area-based measures, the most deprived areas contained higher takeaway outlet densities (p < 0.001). However, in person-centred metrics lower socioeconomic status was associated with lower exposure to takeaway outlets and supermarkets (all home-based exposures p < 0.001) and socioeconomic differences were greatest at the smallest buffer sizes. Socioeconomic differences in

  19. Pigmented villonodular synovitis of the knee: A retrospective analysis of 214 cases at a UK tertiary referral centre.

    Science.gov (United States)

    Patel, K H; Gikas, P D; Pollock, R C; Carrington, R W; Cannon, S R; Skinner, J A; Briggs, T W; Aston, W J S

    2017-08-01

    Pigmented villonodular synovitis (PVNS) is a rare, locally aggressive and potentially recurrent synovial disease. We present the largest single-centre experience of knee PVNS. Our aim was to evaluate our tertiary hospital's experience in the management of knee PVNS. Retrospective data collection of consecutive cases of knee PVNS from 2002 to 2015. In total, 214 cases of knee PVNS were identified which represented 53.4% of all PVNS (12.1% were recurrent at presentation). 100 were localised PVNS (LPVNS), 114 diffuse PVNS (DPVNS) and two malignant PVNS. Knee PVNS was more likely to occur in females with a mean age of 39. Following surgery, 47.6% had recurrence with DPVNS as opposed to 8.6% with LPVNS. In LPVNS, there was no significant difference in recurrence between open and arthroscopic synovectomy (8.7% vs 9.1%, P>0.05). However, in DPVNS, there was a significantly higher risk of recurrence with arthroscopic compared to open synovectomy (83.3% vs 44.8%, RR=1.86 95% CI 1.32-2.62, P=0.0004). PVNS can be difficult to treat. We found no difference in local recurrence rates between open and arthroscopic treatment of LPVNS but significantly increased rates of recurrence for DPVNS following arthroscopic treatment. We would therefore recommend open synovectomy for DPVNS. Crown Copyright © 2017. Published by Elsevier B.V. All rights reserved.

  20. Rates of organ donation in a UK tertiary cardiac arrest centre following out-of-hospital cardiac arrest.

    Science.gov (United States)

    Cheetham, Olivia V; Thomas, Matthew J C; Hadfield, John; O'Higgins, Fran; Mitchell, Claire; Rooney, Kieron D

    2016-04-01

    To ascertain the rate of successful organ donation (OD) within patients who sustained an out of hospital cardiac arrest (OHCA) with initial return of spontaneous circulation (ROSC) and survival to hospital admission, but whom subsequently do not survive to hospital discharge. A retrospective audit of ambulance service and hospital databases from January 2010 to January 2015 was undertaken in a United Kingdom tertiary-referral regional cardiac arrest centre. Crude denominator data for cardiac arrests was obtained from the regional ambulance service; the ICU database was interrogated for OHCA patient admissions and outcomes. Patients who died were cross-referenced against the local Organ Donation service database. Five hundred and fourteen {514} patients were admitted to ICU following OHCA over this five year period. Two hundred and forty-one {241} patients (47%) survived to hospital discharge and 273 (53%) died of whom 106 (39%) were referred to a Specialist Nurse for Organ Donation (SNOD). The conversion rate after the family was approached was 64%. Twenty-eight {28} patients proceeded to donation and 25 patients (24%) successfully donated at least one organ. On average, a patient proceeding to donation provided 1.9 organs. A proactive, systematic approach to OD in OHCA patients can provide a good conversion rate and substantial number of donors. Most donations occur after death from circulatory criteria. There is a positive socio-economic benefit with nearly £4m in savings to the health service within the next 5 years potentially being realised during this period by liberating patients from dialysis. Copyright © 2016. Published by Elsevier Ireland Ltd.

  1. 14 April 2014 - UK University College London Hospitals and National Health Service Foundation Trust Chairman R. Murley in the ATLAS cavern with CERN Head of Medical Applications S. Myers and Collaboration Spokesperson D. Charlton.

    CERN Multimedia

    Gadmer, Jean-Claude

    2014-01-01

    Mr Richard Murley Chairman Sir Robert Naylor Chief Executive University College London Hospitals (UCLH) – National Health Service (NHS) Foundation Trust United Kingdom of Great Britain and Northern Ireland

  2. Centre-level variation of treatment and outcome in 5-year-old children with non-syndromic unilateral cleft lip and palate: The Cleft Care UK study. Part 1: Methodology and results for dento-facial outcomes.

    Science.gov (United States)

    Wills, A K; Mahmoud, O; Hall, A; Sell, D; Smallridge, J; Southby, L; Toms, S; Waylen, A; Wren, Y; Ness, A R; Sandy, J R

    2017-06-01

    Outline methods used to describe centre-level variation in treatment and outcome in children in the Cleft Care UK (CCUK) study. Report centre-level variation in dento-facial outcomes. Two hundred and sixty-eight five-year-old British children with non-syndromic unilateral cleft lip and palate (UCLP). Between January 2011 and December 2012, data were collected on a comprehensive range of outcomes. Child facial appearance and symmetry were assessed using photographic pictures. Dental arch relationships were assessed from standardized dental study models. Hierarchical statistical models were used to predict overall means and the variance partition coefficient (VPC)-a measure of amount of variation in treatment or outcome explained by the centre. Data on dento-alveolar arch relationships and facial appearance were available on 197 and 252 children, respectively. The median age of the children was 5.5 years, and 68% were boys. Variation was described across 13 centres. There was no evidence of centre-level variation in good or poor dento-alveolar arch relationships with a VPC of 4% and 3%, respectively. Similarly, there was no evidence of centre-level variation in good or poor facial appearance with a VPC of 2% and 5%, respectively. There was no evidence of centre-level variation for dento-facial outcomes although this study only had the power to detect large variation between sites. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. Routine Use of Fluoroscopic-Guided Femoral Arterial Puncture to Minimise Vascular Complication Rates in CTO Intervention: Multi-centre UK Experience.

    Science.gov (United States)

    Fairley, Sarah L; Lucking, Andrew J; McEntegart, Margaret; Shaukat, Aadil; Smith, David; Chase, Alexander; Hanratty, Colm G; Spratt, James C; Walsh, Simon J

    2016-12-01

    Chronic total occlusion (CTO) revascularisation has a crucial role in contemporary percutaneous coronary intervention (PCI). Procedural success is influenced by disease complexity, calcific burden and patient characteristics but has substantially improved with the implementation of novel hybrid strategies. However, vascular-access related complications remain a cause of morbidity and mortality. This study aimed to assess the effectiveness of fluoroscopic-guided femoral arterial puncture to minimise this risk during CTO PCI. Standardised data were retrospectively collected from four high-volume UK CTO centres between September 2011 and November 2013. Demographic, clinical and procedural data (vascular access site, sheath size, anticoagulation use) was collated. The anatomical location of the femoral puncture in relation to the femoral bifurcation, femoral head position and inferior epigastric artery were recorded. Adverse events related to vascular access were documented. A total of 528 patients were included (676 femoral punctures) with the majority being male (n=432, 81.8%). Large sheaths (8F) were used in 81.2% of cases. Fluoroscopy-enabled punctures were made in the 'safe zone' in over > 93% of cases. Vascular closure devices (VCD) were used in 88.3% of cases. The adverse event rate per puncture was 0.89%. This study demonstrates an extremely low incidence of vascular-access complications in CTO PCI when fluoroscopic guidance is used to obtain femoral arterial access by default radial operators. Copyright © 2016 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved.

  4. Lidar Observations of Pollution Transport From London to Rural Areas

    Science.gov (United States)

    Ricketts, Hugo; Vaughan, Geraint; Wareing, David

    2016-06-01

    The Clean Air for London (ClearfLo) Project took place in and around London, United Kingdom. The aim of the project was to learn how both atmospheric dynamics and chemistry affect air pollution in the south east of England. During the winter and summer of 2012 many different types of instrument including lidars were deployed throughout London city centre, suburbs and into rural areas. Amongst these instruments was the Boundary Layer Aerosol/Ozone Lidar owned by the National Centre for Atmospheric Sciences (NCAS) in the United Kingdom. Ozone and aerosol data are presented from data collected during July and August 2012 and compared to back trajectories to identify their origins.

  5. News Astronomy: Science and beauty combined Africa: Physics technicians offer valuable skills Conference: ESERA2013 brings researchers together in Cyprus Physics Olympiad: UK team bring home more medals from the Physics Olympics in Copenhagen Physics Tournament: IOC backs Shrewsbury to host IYPT 2014 Conference: MPTL18 looks at the latest multimedia developments Workshop: The selective absorption of light Science on Stage: Illuminating Science Education in London in 2015

    Science.gov (United States)

    2013-11-01

    Astronomy: Science and beauty combined Africa: Physics technicians offer valuable skills Conference: ESERA2013 brings researchers together in Cyprus Physics Olympiad: UK team bring home more medals from the Physics Olympics in Copenhagen Physics Tournament: IOC backs Shrewsbury to host IYPT 2014 Conference: MPTL18 looks at the latest multimedia developments Workshop: The selective absorption of light Science on Stage: Illuminating Science Education in London in 2015

  6. The London Congestion Charge

    National Research Council Canada - National Science Library

    Leape, Jonathan

    2006-01-01

    .... In early 2003, London imposed a congestion charge—a daily charge for driving or parking a vehicle on public roads within central London between the hours of 7:00 a.m. and 6:30 p.m. on workdays...

  7. UK Parkinson's Excellence Network: empowering service improvement across the UK.

    Science.gov (United States)

    Burn, David

    2015-01-01

    Parkinson's UK, together with leading Parkinson's professionals, has set up the UK Parkinson's Excellence Network to bring together the passion and expertise of leading clinicians with the strategic leadership and resources of Parkinson's UK underpinned by the voice of people affected by Parkinson's. Launched in London in February 2015, the Excellence Network aims to drive sustainable improvements in health and social care services. It will provide a more strategic approach to clinical development so that Parkinson's services across health and social care can be transformed to provide the best quality care across the UK.

  8. White Tower, London, England

    OpenAIRE

    William the Conqueror; William Rufus; Henry I

    2007-01-01

    White Tower (Tower of London), London, England. Photograph taken by Terry Barry. There is restoration work being carried out on one of the towers. The White Tower is a central tower at the Tower of London. The great central keep was built by William the Conqueror and finished by his sons and successors, William Rufus and Henry I, around 1087. It is 90 feet high and is of massive construction, the walls varying from 15 feet thickness at the base to almost 11 feet in the upper parts. Above ...

  9. The management for tuberculosis control in Greater London in comparison with that in Osaka City: lessons for improvement of TB control management in Osaka City urban setting.

    Science.gov (United States)

    Ohkado, Akihiro; Williams, Gini; Ishikawa, Nobukatsu; Shimouchi, Akira; Simon, Carter

    2005-07-01

    The tuberculosis (TB) notification in Osaka City has been persistently high compared with other urban areas in Japan. Although the TB notification in Greater London has kept much lower level compared with that in Osaka City, it has been also persistently high compared with other urban areas in the UK. Nonetheless, the contexts of the two cities relating TB control programme as well as the epidemiological situation greatly vary; there must be some lessons to be learnt from each other to improve each TB control programme to tackle against TB more effectively. Comparing the epidemiological situation of TB in both cities, it is obvious that Osaka City suffers TB more than Greater London in terms of the TB notification rate. Concerning the context of the TB control programme, Osaka City has centralised approach with strong local government commitment; Greater London, on the other hand, has an approach that is greatly fragmented but coordinated through voluntary TB Networks. This paper aims to draw some constructive and practical lessons from Greater London TB control management for further improvement of Osaka City TB control management through literature review and interview to health professionals. TB epidemiology in Greater London shows distinct features in the extent of TB in new entrants and TB co-infected with HIV in comparison with those in Osaka City. TB epidemiology in Osaka City is to a great extent specifically related to homeless people whereas in Greater London, this relationship occurs to a lesser extent. Both areas have relatively high TB-notification rates compared with national figures, and they have "TB hot spots" where remarkably high TB-notification rates exist. TB control in Greater London is characterised with decentralised and devolved services to local government health authorities supplemented with co-ordinating bodies across sectors as well as across Greater London. Sector-wide TB Network as well as London TB Group (LTBG) and London TB Nurses

  10. Taaskasutuses London / Marlen Promann

    Index Scriptorium Estoniae

    Promann, Marlen

    2007-01-01

    "100% Disain London" messist, kus peateemaks oli säästlikkus disainis, materjalides, tehnoloogias ja tootmises. Markko Karu jõudis sellel noore disainiettevõtja auhinna finaali (International Young Design Entrepreneur of the Year)

  11. The London Congestion Charge

    National Research Council Canada - National Science Library

    Leape, Jonathan

    2006-01-01

    .... Traffic congestion has declined substantially, and the program is largely popular. This article describes the origins of the London congestion charge, how it overcame practical and theoretical difficulties, and what effects it has had...

  12. Taaskasutuses London / Marlen Promann

    Index Scriptorium Estoniae

    Promann, Marlen

    2007-01-01

    "100% Disain London" messist, kus peateemaks oli säästlikkus disainis, materjalides, tehnoloogias ja tootmises. Markko Karu jõudis sellel noore disainiettevõtja auhinna finaali (International Young Design Entrepreneur of the Year)

  13. Mapping Arts, Health and Higher Education Collaborative Projects in London

    OpenAIRE

    Sheridan, Jill; Pring, Linda

    2007-01-01

    This publication is based on a report commissioned by The London Centre for Arts and Cultural Enterprise (LCACE) and Arts Council England (ACE) who are committed, along with other partners to building and analysing evidence of the impact of arts activity in the health arena. It seeks to map collaborative projects which have taken place in London since 2002 between the arts, health and higher education institutions. The remit for the research defines arts and health as arts-based activities th...

  14. Space in Pentecostal healing practices among Ghanaian migrants in London

    NARCIS (Netherlands)

    Krause, K.

    2014-01-01

    In this article I analyse different spatial practices related to Pentecostal healing, drawing on fieldwork with Pentecostal believers who have migrated from Ghana to London, UK. I explore the relationship between space and the manifestation of the Holy Spirit by looking at how points of contact with

  15. UK Renal Registry 16th annual report: chapter 14 2012 multisite dialysis access audit in England, Northern Ireland and Wales and 2011 PD one year follow-up: national and centre-specific analyses.

    Science.gov (United States)

    Briggs, Victoria; Pitcher, David; Shaw, Catriona; Fluck, Richard; Wilkie, Martin

    2013-01-01

    Dialysis access should be timely, minimise complications and maintain functionality. Good functional access is required for renal replacement therapy (RRT) to be successful. The aim of the combined vascular and peritoneal dialysis access audit was to examine practice patterns with respect to dialysis access and highlight variations in practice between renal centres. The UK Renal Registry collected centre-specific information on vascular and peritoneal access outcome measures including patient demographics, dialysis access type (at start of dialysis and three months after start of dialysis), surgical assessment and access functionality. The combined access audit covered incident haemodialysis (HD) and peritoneal dialysis (PD) patients in 2012 from England, Northern Ireland and Wales. Centres who had reported data on incident PD patients for the previous audit in 2011 were additionally asked to provide one year follow up data for this group. Fifty-one centres in England, Wales and Northern Ireland (representing 82% of all centres) returned data on first access from 3,720 incident HD patients and 1,018 incident PD patients. A strong relationship was seen between surgical assessment and the likelihood of starting HD with an arteriovenous fistula (AVF). Type of first access was related to the length of time known to renal services with higher numbers of AVFs and PD catheters used in patients known to renal services for at least one year. Three month and one year outcomes of HD and PD access were poorly reported. This audit provides information on important patient related outcome measures with the potential to lead to an improvement in access provision. This represents an important advance, however data collection remains suboptimal. There is wide practice variation across the England, Wales and Northern Ireland in provision of both HD and PD access which requires further exploration. © 2014 S. Karger AG, Basel.

  16. What is the role of a specialist regional mesothelioma multidisciplinary team meeting? A service evaluation of one tertiary referral centre in the UK

    OpenAIRE

    Bibby, Anna C; Williams, Katie; Smith, Sarah; Bhatt, Nidhi; Maskell, Nick A

    2016-01-01

    Background Multidisciplinary team meetings are standard care for cancer in the UK and Europe. Professional bodies recommend that mesothelioma cases should be discussed at specialist multidisciplinary team meetings. However, no evidence exists exploring the role of the specialist mesothelioma multidisciplinary team meeting. Objectives To evaluate the clinical activity of 1 specialist mesothelioma multidisciplinary team meeting and to determine how often a definitive diagnosis was made, whethe...

  17. SCHOLARSHIPS AT LONDON MET

    Institute of Scientific and Technical Information of China (English)

    杜松

    2006-01-01

    London Metropolitan University has a widerange of scholarship programmes for internationalstudents.We offer full and partial scholarships tooustandifg students from all over the world. Ourprogrammes include joint scholarships with BBCWorld Service, Asia House, International StudentsHouse and other global organisations.If you have outstanding academic results,and an excellent track record, please see our

  18. Kommunisme i London

    DEFF Research Database (Denmark)

    Hansen, Brian Benjamin; Nielsen, Kasper Porsgaard

    2010-01-01

    Begrebet ”kommunisme” var på dagsordenen, da over 800 mennesker mødtes i Birkbeck University College i London, den 13.-15. marts, 2009. En perlerække af talere var inviteret: Alain Badiou, Michael Hardt, Bruno Bosteels, Peter Hallward, Allesandro Russo, Alberto Toscano, Toni Negri, Terry Eagleton...

  19. Charmed Life in Contemporary London

    DEFF Research Database (Denmark)

    2011-01-01

    Documentary film produced for the Miracles and Charms exhibition at the Wellcome Collection, London......Documentary film produced for the Miracles and Charms exhibition at the Wellcome Collection, London...

  20. CITY OF LONDON: THE SECRETS OF STABILITY

    Directory of Open Access Journals (Sweden)

    M. K. Belyaev

    2010-01-01

    Full Text Available Reasons why the City, oldest London global financial centre, keeps to hold up leading positions in the financial world, are thoroughly discussed. Initially, this phenomenon was explained by dominating position England held as world industrial power. However, the City has not lost its leadership over last decades when England economics suffered bad times. This is explained by traditions, by the history as well as by specific position London holds as place where «business is made» as well as by the trend to «clustering» i.e. concentration characteristic for the market of financial services, all this making it possible for financial companies to cut their costs and to provide their clients with services on more attractive conditions.

  1. Think London, Think china

    Institute of Scientific and Technical Information of China (English)

    Yang Wei

    2008-01-01

    @@ The China-UK relationship has a long history and is one of the most important contemporary China-European ties.The UK was the first western country to recognize the People's Republic of China after it was founded in 1949.Later,the two sides reached an agreement to exchange Charges d'Affairs in 1954,and signed the Joint Communiqué for the Agreement on the Exchange of Ambassadors in 1972.

  2. Transfusion in CMV seronegative T-depleted allogeneic stem cell transplant recipients with CMV-unselected blood components results in zero CMV transmissions in the era of universal leukocyte reduction: a U.K. dual centre experience.

    Science.gov (United States)

    Hall, S; Danby, R; Osman, H; Peniket, A; Rocha, V; Craddock, C; Murphy, M; Chaganti, S

    2015-12-01

    To establish rates of cytomegalovirus (CMV) transmission with use of CMV-unselected (CMV-U), leukocyte-reduced blood components transfused to CMV-seronegative patient/CMV-seronegative donor (CMV neg/neg) allogeneic stem cell transplantation (SCT) recipients including those receiving T-depleted grafts. CMV infection remains a major cause of morbidity following SCT. CMV-seronegative SCT recipients are particularly at risk of transfusion transmitted CMV (TT-CMV) and until recently they have received blood components from CMV-seronegative donors with significant resource implications. Although leukocyte reduction of blood components is reported to minimise risk of TT-CMV, its efficacy in high-risk situations, such as in T-depleted transplant recipients, is unknown. We retrospectively analysed the incidence of TT-CMV in CMV neg/neg allogeneic SCT recipients transfused with CMV-U, leukocyte-reduced blood components in two transplantation centres in the UK. Patients were monitored for CMV infection by weekly CMV polymerase chain reaction testing. Leukocyte reduction of blood components was in accordance with current UK standards. Among 76 patients, including 59 receiving in vivo T-depletion, no episodes of CMV infection were detected. Patients were transfused with 1442 CMV-unselected, leukocyte-reduced components, equating to 1862 donor exposures. Our findings confirm the safety of leukocyte reduction as a strategy in preventing TT-CMV in high-risk allogeneic SCT recipients. © 2015 British Blood Transfusion Society.

  3. Lidar Observations of Pollution Transport From London to Rural Areas

    Directory of Open Access Journals (Sweden)

    Ricketts Hugo

    2016-01-01

    Full Text Available The Clean Air for London (ClearfLo Project took place in and around London, United Kingdom. The aim of the project was to learn how both atmospheric dynamics and chemistry affect air pollution in the south east of England. During the winter and summer of 2012 many different types of instrument including lidars were deployed throughout London city centre, suburbs and into rural areas. Amongst these instruments was the Boundary Layer Aerosol/Ozone Lidar owned by the National Centre for Atmospheric Sciences (NCAS in the United Kingdom. Ozone and aerosol data are presented from data collected during July and August 2012 and compared to back trajectories to identify their origins.

  4. Adidas Eyes Olympics to Take Nike's UK Crown

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    German sportswear maker Adidas plans to use the Olympic Games in London next year to generate 100 million pounds($165 million)of sales in the UK and steal market leadership there from arch rival Nike.

  5. A pilot randomised controlled trial of personalised care for depressed patients with symptomatic coronary heart disease in South London general practices: the UPBEAT-UK RCT protocol and recruitment

    Directory of Open Access Journals (Sweden)

    Tylee André

    2012-06-01

    Full Text Available Abstract Background Community studies reveal people with coronary heart disease (CHD are twice as likely to be depressed as the general population and that this co-morbidity negatively affects the course and outcome of both conditions. There is evidence for the efficacy of collaborative care and case management for depression treatment, and whilst NICE guidelines recommend these approaches only where depression has not responded to psychological, pharmacological, or combined treatments, these care approaches may be particularly relevant to the needs of people with CHD and depression in the earlier stages of stepped care in primary care settings. Methods This pilot randomised controlled trial will evaluate whether a simple intervention involving a personalised care plan, elements of case management and regular telephone review is a feasible and acceptable intervention that leads to better mental and physical health outcomes for these patients. The comparator group will be usual general practitioner (GP care. 81 participants have been recruited from CHD registers of 15 South London general practices. Eligible participants have probable major depression identified by a score of ≥8 on the Hospital Anxiety and Depression Scale depression subscale (HADS-D together with symptomatic CHD identified using the Modified Rose Angina Questionnaire. Consenting participants are randomly allocated to usual care or the personalised care intervention which involves a comprehensive assessment of each participant’s physical and mental health needs which are documented in a care plan, followed by regular telephone reviews by the case manager over a 6-month period. At each review, the intervention participant’s mood, function and identified problems are reviewed and the case manager uses evidence based behaviour change techniques to facilitate achievement of goals specified by the patient with the aim of increasing the patient’s self efficacy to solve their

  6. "Every morning before you open the door you have to watch for that brown envelope": complexities and challenges of undertaking oral history with Ethiopian forced migrants in London, UK.

    Science.gov (United States)

    Palmer, David

    2010-01-01

    The experience, "voice," and perceptions of the "individual refugee" is conspicuous by its virtual absence from academic research. The few studies dealing with black adn minority ethnic experiences from an emic perspective in relation to mental health do not specifically refer to refugees or asylum seekers. This article explores the use of oral history techniques when researching Ethiopian forced migrants in the U.K. Based on two pilot research projects which explored Ethiopian culture and experience in reference to mental health adn well-being, it will focus on some of the complexities and challenges encountered. This article acknowledges the need for an understanding of cultural traditions as well as history and experience when planning and implementing such research as this proved to be an essential part of the research process, ensuring that individual stories and truths were allowed to evolve. The oral history approach for this research therefore ensured that the experiential knowledge of the Ethiopian forced migrant participants was given space, authenticity, and validity.

  7. 23rd May 2011 - University of Liverpool Pro-Vice-Chancellor and Public Orator K. Everest (UK) Mrs Everest in the ATLAS visitor centre with Collaboration Deputy Spokesperson D. Charlton, in LHCb surface building with Collaboration Spokesperson A. Golutvin, accompanied throughout by P. Wells and Liverpool University T. Bowcock and M. Klein.

    CERN Document Server

    Maximilen Brice

    2011-01-01

    23rd May 2011 - University of Liverpool Pro-Vice-Chancellor and Public Orator K. Everest (UK) Mrs Everest in the ATLAS visitor centre with Collaboration Deputy Spokesperson D. Charlton, in LHCb surface building with Collaboration Spokesperson A. Golutvin, accompanied throughout by P. Wells and Liverpool University T. Bowcock and M. Klein.

  8. Impact on and use of health services by international migrants: questionnaire survey of inner city London A&E attenders

    Directory of Open Access Journals (Sweden)

    Eliahoo Joseph

    2006-11-01

    Full Text Available Abstract Background Changing immigration trends pose new challenges for the UK's open access health service and there is considerable speculation that migrants from resource-poor countries place a disproportionate burden on services. Data are needed to inform provision of services to migrant groups and to ensure their access to appropriate health care. We compared sociodemographic characteristics and impact of migrant groups and UK-born patients presenting to a hospital A&E/Walk-In Centre and prior use of community-based General Practitioner (GP services. Methods We administered an anonymous questionnaire survey of all presenting patients at an A&E/Walk-In Centre at an inner-city London hospital during a 1 month period. Questions related to nationality, immigration status, time in the UK, registration and use of GP services. We compared differences between groups using two-way tables by Chi-Square and Fisher's exact test. We used logistic regression modelling to quantify associations of explanatory variables and outcomes. Results 1611 of 3262 patients completed the survey (response rate 49.4%. 720 (44.7% were overseas born, representing 87 nationalities, of whom 532 (73.9% were new migrants to the UK (≤10 years. Overseas born were over-represented in comparison to local estimates (44.7% vs 33.6%; p Conclusion Recently arrived migrants are a diverse and substantial group, of whom migrants from refugee-generating countries and asylum seekers comprise only a minority group. Service reorganisation to ensure improved access to community-based GPs and delivery of more appropriate care may lessen their impact on acute services.

  9. OT {-(Uk} / ET {-(Uk}

    Directory of Open Access Journals (Sweden)

    Dr. İbrahim TAŞ

    2008-05-01

    Full Text Available The {-(Uk} affix, expressing the verb result and derivingqualifications, is not seen among the the rules of vowels, rounded-unroundedat old Turkic and middle Turkic texts. But in some words, rounded -unrounded rule is seen. At this text, we investigated some of these words.

  10. The development and implementation of the structured training programme for caregivers of inpatients after stroke (TRACS) intervention: the London Stroke Carers Training Course.

    Science.gov (United States)

    Forster, Anne; Dickerson, Josie; Melbourn, Anne; Steadman, Jayne; Wittink, Margreet; Young, John; Kalra, Lalit; Farrin, Amanda

    2015-03-01

    To describe the content and delivery of the adapted London Stroke Carers Training Course intervention evaluated in the Training Caregivers after Stroke (TRACS) trial. The London Stroke Carers Training Course is a structured training programme for caregivers of inpatients who are likely to return home after their stroke. The course was delivered by members of the multidisciplinary team while the patient was in the stroke unit with one recommended 'follow through' session after discharge home. The intervention consists of 14 training components (six mandatory) that were identified as important knowledge/skills that caregivers would need to be able to care for the stroke patient after discharge home. Following national training days, the London Stroke Carers Training Course was disseminated to intervention sites by the cascade method of implementation. The intervention was adapted for implementation across a range of stroke units. Training days were well attended (median 2.5 and 2.0 attendees per centre for the first and second days, respectively) and the feedback positive, demonstrating 'face validity' for the intervention. However cascading of this training to other members of the multidisciplinary team was not consistent, with 7/18 centres recording no cascade training. The adapted London Stroke Carers Training Course provided a training programme that could be delivered in a standardised, structured way in a variety of stroke unit settings throughout the UK. The intervention was well received by stroke unit staff, however, the cascade method of implementation was not as effective as we would have wished. © The Author(s) 2014.

  11. SPRUCE Mashup London

    Directory of Open Access Journals (Sweden)

    Edward M. Corrado

    2013-01-01

    Full Text Available SPRUCE digital preservation mashups are a series of unique events that are being organized in the United Kingdom to bring together digital preservation practitioners and developers to work on real-world digital preservation challenges. During the 3-day event the digital preservation developers work to create practical solutions to real-world challenges the practitioners are having related to digital preservation. Meanwhile, the practitioners work to create compelling business cases for digital preservation at their institution. This article describes the SPRUCE Mashup London event held in September 2012.

  12. Quality, bias and service user experience in healthcare: 10 years of mental health guidelines at the UK National Collaborating Centre for Mental Health.

    Science.gov (United States)

    Kendall, Tim; Glover, Naomi; Taylor, Clare; Pilling, Stephen

    2011-08-01

    The guideline programme developed by the National Collaborating Centre for Mental Health (NCCMH) for the National Institute for Health and Clinical Excellence (NICE) is probably the most comprehensive and methodologically advanced mental health guideline programme in the world, covering most adults and children with mental health problems and addressing a broad range of pharmacological and psychological/psychosocial interventions. As the success of the NICE programme gains momentum, its influence in the National Health Service (NHS) grows. If guidelines contain systematic bias the effects will be widespread. Over the last 10 years the NCCMH has recognized imperfections and patterns of bias in the way that evidence is generated and included in guidelines, including psychological/psychosocial interventions and drug treatments. The pharmaceutical industry remains a major source of bias through selective reporting and publishing, and represents a threat to ensuring the evidence underpinning guidelines and clinical decision-making is as complete and reliable as possible. The inclusion of service users into guideline development at the NCCMH has developed in parallel to the identification and understanding of evidential bias, and is now becoming an important focus for high-quality guidelines which are becoming increasingly person-centred. For mental health this is as radical as the integration of psychological/psychosocial treatments into what has, for many years, been a largely medical domain. The future role of service users in monitoring their own experience of care and ensuring that trusts are accountable to them is now a real possibility and is likely to have an impact upon the traditional power relations in mental health and the stigma usually associated with psychiatric problems.

  13. Non-contact low-frequency ultrasound therapy compared with UK standard of care for venous leg ulcers: a single-centre, assessor-blinded, randomised controlled trial.

    Science.gov (United States)

    White, Judith; Ivins, Nicola; Wilkes, Antony; Carolan-Rees, Grace; Harding, Keith G

    2016-10-01

    'Hard-to-heal' wounds are those which fail to heal with standard therapy in an orderly and timely manner and may warrant the use of advanced treatments such as non-contact low-frequency ultrasound (NLFU) therapy. This evaluator-blinded, single-site, randomised controlled trial, compared NLFU in addition to UK standard of care [SOC: (NLFU + SOC)] three times a week, with SOC alone at least once a week. Patients with chronic venous leg ulcers were eligible to participate. All 36 randomised patients completed treatment (17 NLFU + SOC, 19 SOC), and baseline demographics were comparable between groups. NLFU + SOC patients showed a -47% (SD: 38%) change in wound area; SOC, -39% (38%) change; and difference, -7·4% [95% confidence intervals (CIs) -33·4-18·6; P = 0·565]. The median number of infections per patient was two in both arms of the study and change in quality of life (QoL) scores was not significant (P = 0·490). NLFU + SOC patients reported a substantial mean (SD) reduction in pain score of -14·4 (14·9) points, SOC patients' pain scores reduced by -5·3 (14·8); the difference was -9·1 (P = 0·078). Results demonstrated the importance of high-quality wound care. Outcome measures favoured NLFU + SOC over SOC, but the differences were not statistically significant. A larger sample size and longer follow-up may reveal NLFU-related improvements not identified in this study.

  14. Should "Teacher Centred Teaching" Replace "Student Centred Learning"?

    Science.gov (United States)

    Bailey, Patrick D.

    2008-01-01

    Mission statements of most HEIs across the UK support "student centred learning". In this paper, it is suggested that "teacher centred teaching" should also have a major role to play, improving the quality of the learning experience in higher education. Students are extremely diverse in their skills, weaknesses, and learning…

  15. Management of obstetric postpartum hemorrhage: a national service evaluation of current practice in the UK

    Directory of Open Access Journals (Sweden)

    Al Wattar BH

    2017-01-01

    Full Text Available Bassel H Al Wattar,1,* Jennifer A Tamblyn,2,* William Parry-Smith,2,* Mathew Prior,3,* Helen Van Der Nelson4,* On behalf of UK Audit and Research trainee Collaborative in Obstetrics and Gynaecology (UKARCOG 1Women’s Health Research Unit, Barts and the London School of Medicine and Dentistry, Queen Mary University London, London, UK; 2Institute of Metabolism and Systems Research (IMSR, University of Birmingham, Birmingham, UK; 3Division of Child Health, Obstetrics & Gynaecology, School of Medicine, University of Nottingham, Nottingham, UK; 4Academic Centre for Women’s Health, North Bristol NHS Trust, Bristol, UK *UKARCOG Background: Postpartum hemorrhage (PPH continues to be one of the major causes of maternal mortality and morbidity in obstetrics. Variations in practice often lead to adverse maternity outcomes following PPH. Our objective was to assess the current practice in managing PPH in the UK.Methods: We performed a national multicenter prospective service evaluation study over one calendar month and compared the current performance to national standards for managing PPH. We used a standardized data collection tool and collected data on patients’ demographics, incidence of PPH, estimated blood loss (EBL, prophylactic and treatment measures, onset of labor, and mode of delivery.Results: We collected data from 98 obstetric units, including 3663 cases of primary PPH. Fifty percent of cases were minor PPH (EBL 500–1000 mL, n=1900/3613, 52.6% and the remaining were moderate PPH (EBL >1000 to <2000 mL, n=1424/3613, 39.4% and severe PPH (EBL >2000 mL, n=289/3613, 8%. The majority of women received active management of the third stage of labor (3504/3613, 97% most commonly with Syntometrine intramuscular (1479/3613, 40.9%. More than half required one additional uterotonic agent (2364/3613, 65.4% most commonly with Syntocinon intravenous infusion (1155/2364, 48.8%. There was a poor involvement of consultant obstetricians and anesthetists in

  16. Clean Air for London (CLEARFLO) Final Campaign Summary

    Energy Technology Data Exchange (ETDEWEB)

    Worsnop, D. R. [Aerodyne Research, Inc., Billerica, MA (United States); Williams, L. R. [Aerodyne Research, Inc., Billerica, MA (United States); Herndon, S. C. [Aerodyne Research, Inc., Billerica, MA (United States); Dubey, M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Ng, N. L. [Georgia Inst. of Technology, Atlanta, GA (United States); Thornton, J. [Univ. of Washington, Seattle, WA (United States); Knighton, B. [Montana State Univ., Bozeman, MT (United States); Coulter, R. [Argonne National Lab. (ANL), Argonne, IL (United States); Prévôt, Ash [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    2016-03-01

    This field campaign funded the participation of scientists from seven different research groups and operated over thirty instruments during the Winter Intensive Operating Period (January-February 2012) of the Clean Air for London (ClearfLo) campaign. The campaign took place at a rural site in Detling, UK, 45 kilometers southeast of central London. The primary science questions for the ClearfLo winter IOP (intensive operational periods) were: 1) “what is the urban increment of particulate matter (PM) and other pollutants in the greater London area?” and 2) “what is the contribution of solid fuel use for home heating to wintertime PM?” An additional motivation for the Detling measurements was the question of whether coatings on black carbon particles enhance absorption.

  17. Connected or informed?: Local Twitter networking in a London neighbourhood

    Directory of Open Access Journals (Sweden)

    John Bingham-Hall

    2015-08-01

    Full Text Available This paper asks whether geographically localised, or ‘hyperlocal’, uses of Twitter succeed in creating peer-to-peer neighbourhood networks or simply act as broadcast media at a reduced scale. Literature drawn from the smart cities discourse and from a UK research project into hyperlocal media, respectively, take on these two opposing interpretations. Evidence gathered in the case study presented here is consistent with the latter, and on this basis we criticise the notion that hyperlocal social media can be seen as a community in itself. We demonstrate this by creating a network map of Twitter followers of a popular hyperlocal blog in Brockley, southeast London. We describe various attributes of this network including its average degree and clustering coefficient to suggest that a small and highly connected cluster of visible local entities such as businesses form a clique at the centre of this network, with individual residents following these but not one another. We then plot the locations of these entities and demonstrate that sub-communities in the network are formed due to close geographical proximity between smaller sets of businesses. These observations are illustrated with qualitative evidence from interviews with users who suggest instead that rather than being connected to one another they benefit from what has been described as ‘neighbourhood storytelling’. Despite the limitations of working with Twitter data, we propose that this multi-modal approach offers a valuable way to investigate the experience of using social media as a communication tool in urban neighbourhoods.

  18. Reform of the London Stock Exchange: the prudential issues

    Directory of Open Access Journals (Sweden)

    M.J.B. HALL

    2013-12-01

    Full Text Available In October 1986 the London Stock Exchange underwent what was termed the Big Bang. This consisted of the removal of fixed commissions on UK securities transactions, the abolition of the single capacity system, and the removal of barriers to entry to UK securities markets. The author considers five prudential issues raised by this event: monopoly power and foreign dominance, international supervisory harmonisation, capital adequacy and managerial competence, the management of 'fall out' (exit from the industry, and conflicts of interest. Three further factors are considered in detail; the regulator's approach to conflicts of interest, the regulation of financial conglomerates, and the implications of the Financial Services Act.

  19. Developing Integrated Care Teams Across the North West London System

    OpenAIRE

    O'Halloran, Katherine Anne

    2016-01-01

    The health needs of the North West London population are changing. People are generally living longer and as a result a growing number are suffering from complex, long-term health conditions. This inevitably creates pressure on available services, to the point where there is a need to look at how these can be better provided. In North West London, the way hospitals and community health services are provided is being transformed to deliver a more co-ordinated and person centred service, achiev...

  20. A London shop window for PPARC industry partnership successes

    CERN Multimedia

    Neale, R

    2002-01-01

    The UK Particle Physics and Astronomy Research Council recently held a seminar in London to reveal the results of the impressive work they are doing in fostering partnerships between science and industry. They have many different types of funded programmes, the purpose of all of them is to encourage industry and entrepreneurs to both benefit from and service the requirements of particle physics science and technology (1 page).

  1. The Olympic legacy: feeding London

    NARCIS (Netherlands)

    Janssens, F.

    2012-01-01

    Over the last decades, the Olympic Games have increasingly claimed to deliver a social and economic ‘legacy’ to the host city. The 2012 Olympic Games in London have set out to deliver a legacy of better food for east London, an area perceived as ‘deprived’, with higher than average rates of obesity

  2. Counting eyeballs, soundbites and 'plings': Arts participation, strategic instrumentalism and the London 2012 Cultural Olympiad

    OpenAIRE

    Gilmore, Abigail

    2012-01-01

    This article examines cultural participation, its metrics and 'drivers' as they are defined through cultural programming for the London 2012 Olympics. The meanings and interpretation of these terms are considered by examining the development of an evaluation framework for the We Play programme in the North West of England, an initiative funded by Legacy Trust UK and part of the London 2012 Cultural Olympiad. It argues that in spite of the dissonance between arts and sports within Olympics pro...

  3. Optical legacy of Imperial College London

    Science.gov (United States)

    Kidger Webb-Moore, Tina E.

    2016-10-01

    The Industrial Revolution, beginning primarily in the UK, generated an increasing need for highly skilled technical people. Throughout the 19th century, technical instruction increased dramatically and the formation of schools specializing in science and technology grew quickly. In England, there was much motivation in favour of a national prestige center for science and technology centered in London. Central among the motivating forces was Queen Victoria's husband, Prince Albert. Although there were already existing specialist science and technology institutions in major English cities, the growth of superior institutions in other countries within Europe, especially Germany and the Charlottenburg area of Berlin (e.g., the Berlin Technical High School), encouraged important English dignitaries to become more competitive with continental Europe. As a result of this strong continental motivation, several science and technology institutions were built in the south Kensington part of London during the latter half of the 19th century. Imperial College, founded at the start of the 20th century, was a culmination and consolidation of several of these 19th century English institutions. Optical science and technology was an early beneficiary of the founding of Imperial College. This paper will attempt to provide the reader with an understanding of how great was the influence of the optical section of Imperial College in the further development of the world's optical science and technology.

  4. William Blake:London VS William Wordsworth:London, 1802

    Institute of Scientific and Technical Information of China (English)

    涂莉媛

    2013-01-01

    Blake and Wordsworth are all important representatives of romantic poets. Though Blake is 13 years older than Word⁃sworth, they are both concerned with human beings, especially the lives of lower class. The poem, London and London, 1802 were created in different time, but they both reflect the miserable lives of common people during industrial revolution period to some extent. This article compares some similarities and differences between the two poems.

  5. Summary of inaugural meeting of the Skin Care in Organ Recipients Group, UK, held at the Royal Society of Medicine, 7 October 2004.

    Science.gov (United States)

    Eedy, D J

    2005-07-01

    This summarizes a meeting held in London at the Royal Society of Medicine, which was brought together by Prof. Fenella Wojnarowska, Professor of Dermatology at Churchill Hospital, Oxford and cofounder of Skin Care in Organ Recipients, UK (SCOR.UK).

  6. Lipoedema: the first UK patient survey.

    Science.gov (United States)

    Evans, Suzanne

    2013-04-01

    Lipoedema UK was founded in 2012 by women with lipoedema and clinicians working in the Lymphoedema Service at St George's Hospital in London. Its patron is Professor Peter Mortimer, the UK's leading Lipoedema expert, and its nurse consultant is Sandy Ellis, who diagnoses and treats many women with Lipoedema in the UK and is also the nurse consultant in the St George's team. The charity's objectives are to educate doctors, health professionals and the public about lipoedema and its symptoms, so it may be diagnosed and treated earlier.

  7. Novel Approaches to the Treatment of Cancer in London UK

    Directory of Open Access Journals (Sweden)

    Judith Black

    2015-03-01

    Full Text Available An intensive and in-depth two-day conference providing an advanced level updateKEY TOPICS TO BE COVERED:New paradigms for targeted therapiesNew anti-cancer agents ~ industry viewpointNovel approaches to the treatment of breast cancer, melanoma and pancreatic cancerDrug development and precision radiotherapyEuropean drug development initiativesMarket access to novel cancer drugsRegulatory issues in marketing authorisation of anti-cancer productsGene and cell therapies and trial endpointsDeveloping cancer vaccinesCLICK HERE for more information 

  8. Investigating public space exploration support in the UK

    Science.gov (United States)

    Entradas, Marta; Miller, Steve

    2010-10-01

    Space agencies such as NASA and ESA have ambitious long-term programmes that mark the beginning of a new era in space exploration where humans will land on Mars; an era requiring public support and, therefore, more consideration for public opinion. Empirical research shows that there are substantial differences in the level of understanding of space exploration among the general public. Studying audiences appears to be crucial to inform public engagement and communication strategies as well as policy debate. This paper presents the results of a survey conducted in the UK in 2008 at two science outreach events, the Royal Society Exhibition in London and the National Space Centre in Leicester, to investigate the motivations, beliefs, political preferences and attitudes towards space exploration of this audience. A sample of 744 respondents was collected. The analysis shows that the British public who come to outreach and engagement activities support space exploration but have some reservations about considering the advancement of UK space activities to be of national interest. Yet, when asked about means of exploring space, the majority agrees that space should be explored using both mankind and machines, ranking "generating new scientific knowledge and advancing human culture" as the most important reason for continuing investment in space research. Although the greater number of supporters says that more than the current government funding should be allocated to civil space activities, concerns about risk and value appear to influence this view.

  9. [The Freud Museum in London as a research centre].

    Science.gov (United States)

    Molnar, Michael; Tögel, Christfried

    2006-01-01

    The paper presents a compact description of those resources of the Freud Museum most relevant for the Freud scholar: 1. the Archives with its collection of letters, documents, photos, and press cuttings from the 1920s and 1930s, as well as reproductions of paintings and photos of tourist features, compiled by Freud himself; 2. Freud's archaeological collection; 3. Freud's library.

  10. Pan-London tuberculosis services: a service evaluation

    Directory of Open Access Journals (Sweden)

    Belling Ruth

    2012-07-01

    Full Text Available Abstract Background London has the largest proportion of tuberculosis (TB cases of any western European capital, with almost half of new cases drug-resistant. Prevalence varies considerably between and within boroughs with research suggesting inadequate control of TB transmission in London. Economic pressures may exacerbate the already considerable challenges for service organisation and delivery within this context. This paper presents selected findings from an evaluation of London’s TB services’ organisation, delivery, professional workforce and skill mix, intended to support development of a strategic framework for a pan-London TB service. These may also interest health service professionals and managers in TB services in the UK, other European cities and countries and in services currently delivered by multiple providers operating independently. Methods Objectives were: 1 To establish how London’s TB services are structured and delivered in relation to leadership, management, organisation and delivery, coordination, staffing and support; 2 To identify tools/models for calculating skill mix as a basis for identifying skill mix requirements in delivering TB services across London; 3 To inform a strategic framework for the delivery of a pan-London TB service, which may be applicable to other European cities. The multi-method service audit evaluation comprised documentary analysis, semi-structured interviews with TB service users (n = 10, lead TB health professionals and managers (n = 13 representing London’s five sectors and focus groups with TB nurses (n = 8 and non-London network professionals (n = 2. Results Findings showed TB services to be mainly hospital-based, with fewer community-based services. Documentary analysis and professionals’ interviews suggested difficulties with early access to services, low suspicion index amongst some GPs and restricted referral routes. Interviews indicated lack of managed

  11. Teachers' Experiences of Autonomy in Continuing Professional Development: Teacher Learning Communities in London and Hong Kong

    Science.gov (United States)

    Hargreaves, Eleanore; Berry, Rita; Lai, Y. C.; Leung, Pamela; Scott, David; Stobart, Gordon

    2013-01-01

    This paper examines teachers' experiences of autonomy as they undertook Continuing Professional Development (CPD) in the form of Teacher Learning Communities (TLCs) to develop Assessment for Learning (AfL). Participant teacher interview data were used from two parallel TLC projects, one in Hong Kong and one in London, UK. Autonomy was defined in…

  12. Teachers' Experiences of Autonomy in Continuing Professional Development: Teacher Learning Communities in London and Hong Kong

    Science.gov (United States)

    Hargreaves, Eleanore; Berry, Rita; Lai, Y. C.; Leung, Pamela; Scott, David; Stobart, Gordon

    2013-01-01

    This paper examines teachers' experiences of autonomy as they undertook Continuing Professional Development (CPD) in the form of Teacher Learning Communities (TLCs) to develop Assessment for Learning (AfL). Participant teacher interview data were used from two parallel TLC projects, one in Hong Kong and one in London, UK. Autonomy was defined in…

  13. Analyzing the Roles, Activities, and Skills of Learning Technologists: A Case Study from City University London

    Science.gov (United States)

    Fox, Olivia; Sumner, Neal

    2014-01-01

    This article reports on a case study carried out at City University London into the role of learning technologists. The article examines how the role developed by providing points of comparison with a report on the career development of learning technology staff in UK universities in 2001. This case study identified that learning technologists…

  14. Analyzing the Roles, Activities, and Skills of Learning Technologists: A Case Study from City University London

    Science.gov (United States)

    Fox, Olivia; Sumner, Neal

    2014-01-01

    This article reports on a case study carried out at City University London into the role of learning technologists. The article examines how the role developed by providing points of comparison with a report on the career development of learning technology staff in UK universities in 2001. This case study identified that learning technologists…

  15. The Wrong Side of the Tracks: Starting School in a Socially Disadvantaged London Borough

    Science.gov (United States)

    Alsford, Elizabeth; Ralephata, Andrew; Bolderson, Sarah; Curtin, Martina; Parish, Esther; Klaber, Victoria; Griffin, Sue; Nash, Lisa; Cullen, Rachel; Musoke, Brenda; Bhalla, Sangheeta; Walker, Lindsay; Duffer, Luisa; O'Sullivan, Sylvia; Knowland, Victoria; Cozens, Suzanne; McLaren, Lindsey; Camilleri, Bernard; Halil, Suzan; Furze, Rachael; Leung, Wai; O'Gorman, Ciara; Carver, Verity; Young, Dorothy; Pring, Tim

    2017-01-01

    Substantial evidence exists that social circumstances can affect children's language development. As a result many children in socially deprived areas start school with delayed language, which may persist and adversely affect their attainment. We assessed the language of children in seven reception classes in a London (UK) borough and followed the…

  16. London Tideway Tunnels: tackling London's Victorian legacy of combined sewer overflows.

    Science.gov (United States)

    Thomas, G B; Crawford, D

    2011-01-01

    It takes a few millimetres of rainfall to cause the 34 most polluting combined sewer overflows (CSOs) to discharge into the River Thames. Currently, in a typical year, spillages to the tidal reaches of the River Thames occur about 60 times, with an estimated spill volume of 39 million cubic metres. Both the UK Government and the European Union have determined that the CSO discharges have an adverse environmental impact on fish species, introduce unacceptable aesthetics and elevate the health risks for recreational users of the Thames, with a frequency of discharge which is in breach of the Urban Wastewater Treatment Directive. Studies have established that the environmental objectives can be fully met on the most cost-effective basis by completing both quality improvements to treatment works and by the provision of a storage and transfer tunnel to intercept unsatisfactory CSOs. Extensive modelling has been undertaken to develop an optimised solution. In parallel with the design development a rigorous and comprehensive site selection methodology has been established to select sites and consult stakeholders and the public on the preferred sites and scheme, with the first stage of public consultation planned for later in 2010. The London Tideway Tunnels are an essential part of the delivery of improvements to the water quality of the tidal River Thames, and this ambitious, historic scheme represents a vital strategic investment in London's infrastructure.

  17. Deaths of cyclists in london: trends from 1992 to 2006

    Directory of Open Access Journals (Sweden)

    Lee William E

    2010-11-01

    Full Text Available Abstract Background Cycling is an increasingly important mode of transport for environmental and health reasons. Cycling fatalities in London were previously investigated in 1994 using routinely collected data. Since then, there have been shifts in the modes of transport used, and in transport policies. We sought to replicate the previous work using data on cyclist deaths in London between 1992 and 2006, specifically investigating whether heavy goods vehicles continued to pose a threat. Methods Observational study based on analysis of time series of police road casualties data, 1992 to 2006, in London, UK. The main outcome measures were cyclists killed in road traffic collisions. Poisson regression and chi-squared test for homogeneity were used to assess time effects. Travel flow data was then used to estimate annual fatality rates per 100,000 cyclists per kilometre. Results From 1992 to 2006 there was a mean of 16 cycling fatalities per year (range 8-21. 146 deaths (60% were in inner London and 96 in outer London. There was no evidence for a decline over time (p = 0.7 other than a pronounced dip in 2004 when there were 8 fatalities. Freight vehicles were involved in 103 of 242 (43% of all incidents and the vehicle was making a left turn in over half of these (53%. The fatality rate ranged from 20.5 deaths in 1992 to 11.1 deaths in 2006 per 100,000 estimated cyclists per kilometre (rate ratio 0.54, 95% confidence interval 0.28 to 1.03. Conclusions There is little evidence fatality rates have fallen. Freight vehicles over 3.5 tonnes continue to present a disproportionate threat; they should be removed from urban roads and more appropriate means of delivery of essential goods found.

  18. Space in Pentecostal healing practices among Ghanaian migrants in London.

    Science.gov (United States)

    Krause, Kristine

    2014-01-01

    In this article I analyze different spatial practices related to Pentecostal healing, drawing on fieldwork with Pentecostal believers who have migrated from Ghana to London, UK. I explore the relationship between space and the manifestation of the Holy Spirit by looking at how points of contact with the divine are created in the personal life of people and at the sites where the casting out of demons takes place. Unlike in other spirit-centered healing traditions, the Christian Holy Spirit is not conceived of as embodied in specific places, but rather is spatially unbound. To manifest, however, the Holy Spirit requires specific spatial qualities and esthetics.

  19. Eye casualty services in London

    Science.gov (United States)

    Smith, H B; Daniel, C S; Verma, S

    2013-01-01

    The combined pressures of the European Working Time Directive, 4 h waiting time target, and growing rates of unplanned hospital attendances have forced a major consolidation of eye casualty departments across the country, with the remaining units seeing a rapid increase in demand. We examine the effect of these changes on the provision of emergency eye care in Central London, and see what wider lessons can be learned. We surveyed the managers responsible for each of London's 8 out-of-hours eye casualty services, analysed data on attendance numbers, and conducted detailed interviews with lead clinicians. At London's two largest units, Moorfields Eye Hospital and the Western Eye Hospital, annual attendance numbers have been rising at 7.9% per year (to 76 034 patients in 2010/11) and 9.6% per year (to 31 128 patients in 2010/11), respectively. Using Moorfields as a case study, we discuss methods to increase capacity and efficiency in response to this demand, and also examine some of the unintended consequences of service consolidation including patients travelling long distances to geographically inappropriate units, and confusion over responsibility for out-of-hours inpatient cover. We describe a novel ‘referral pathway' developed to minimise unnecessary travelling and delay for patients, and propose a forum for the strategic planning of London's eye casualty services in the future. PMID:23370420

  20. London´s erotic masterpiece

    DEFF Research Database (Denmark)

    Kerchlango, Jørg

    2004-01-01

    Londoners call it the erotic ghurkin. Architects proclaim Norman Foster´s new building a revolutionary masterwork......Londoners call it the erotic ghurkin. Architects proclaim Norman Foster´s new building a revolutionary masterwork...

  1. Olympics Legacy: the London Olympics 2012

    OpenAIRE

    2010-01-01

    The reasons for proposing a London 2012 bid are outlined in the light of London city planning over the past sixty years. The processes influencing the bid for the London 2012 Olympics are investigated in respect of the lessons from Barcelona and Sydney. The role of environmental and landscape improvement is examined and the importance of legacy is described and analysed. The cost of Olympiads since Sydney 2000 are described and compared. Then progress of the London 2012 Olympics developmen...

  2. Tracer concentration profiles measured in central London as part of the REPARTEE campaign

    Science.gov (United States)

    Martin, D.; Petersson, K. F.; White, I. R.; Henshaw, S. J.; Nickless, G.; Lovelock, A.; Barlow, J. F.; Dunbar, T.; Wood, C. R.; Shallcross, D. E.

    2011-01-01

    There have been relatively few tracer experiments carried out that have looked at vertical plume spread in urban areas. In this paper we present results from two tracer (cyclic perfluorocarbon) experiments carried out in 2006 and 2007 in central London centred on the BT Tower as part of the REPARTEE (Regent's Park and Tower Environmental Experiment) campaign. The height of the tower gives a unique opportunity to study vertical dispersion profiles and transport times in central London. Vertical gradients are contrasted with the relevant Pasquill stability classes. Estimation of lateral advection and vertical mixing times are made and compared with previous measurements. Data are then compared with a simple operational dispersion model and contrasted with data taken in central London as part of the DAPPLE campaign. This correlates dosage with non-dimensionalised distance from source. Such analyses illustrate the feasibility of the use of these empirical correlations over these prescribed distances in central London.

  3. Tracer concentration profiles measured in central London as part of the REPARTEE campaign

    Directory of Open Access Journals (Sweden)

    D. Martin

    2011-01-01

    Full Text Available There have been relatively few tracer experiments carried out that have looked at vertical plume spread in urban areas. In this paper we present results from two tracer (cyclic perfluorocarbon experiments carried out in 2006 and 2007 in central London centred on the BT Tower as part of the REPARTEE (Regent's Park and Tower Environmental Experiment campaign. The height of the tower gives a unique opportunity to study vertical dispersion profiles and transport times in central London. Vertical gradients are contrasted with the relevant Pasquill stability classes. Estimation of lateral advection and vertical mixing times are made and compared with previous measurements. Data are then compared with a simple operational dispersion model and contrasted with data taken in central London as part of the DAPPLE campaign. This correlates dosage with non-dimensionalised distance from source. Such analyses illustrate the feasibility of the use of these empirical correlations over these prescribed distances in central London.

  4. Incremental validity of WISC-IV(UK) factor index scores with a referred Irish sample: predicting performance on the WIAT-II(UK.).

    Science.gov (United States)

    Canivez, Gary L; Watkins, Marley W; James, Trevor; Good, Rebecca; James, Kate

    2014-12-01

    Subtest and factor scores have typically provided little incremental predictive validity beyond the omnibus IQ score. This study examined the incremental validity of Wechsler Intelligence Scale for Children - Fourth UK Edition (WISC-IV(UK) ; Wechsler, 2004a, Wechsler Intelligence Scale for Children - Fourth UK Edition, Harcourt Assessment, London, UK) and factor index scores in predicting academic achievement on the Wechsler Individual Achievement Test - Second UK Edition (WIAT-II(UK) ; Wechsler, 2005a, Wechsler Individual Achievement Test-Second UK Edition, Pearson, London, UK), beyond that predicted by the WISC-IV(UK) FSIQ. The sample included 1,014 Irish children (ages 6-0 to 16-9) who were referred for evaluation of learning difficulties. Hierarchical multiple regression analyses were used with the WISC-IV(UK) FSIQ (Block 1) and factor index scores (Block 2) as predictors and WIAT-II(UK) subtest and composite scores as dependent variables. The WISC-IV(UK) FSIQ accounted for statistically significant and generally large portions of WIAT-II(UK) subtest and composite score variance. WISC-IV(UK) factor index scores combined to provide statistically significant increments in prediction of most WIAT-II(UK) subtest and composite scores over and above the FSIQ; however, the effect sizes were mostly small as previously observed (i.e., Canivez, 2013a, Psychol. Assess., 25, 484; Glutting et al., 2006, J. Spec. Educ., 40, 103; Nelson et al., 2013, Psychol. Assess., 25, 618). Individually, the WISC-IV(UK) factor index scores provided small unique contributions to predicting WIAT-II(UK) scores. This, in combination with studies of apportioned variance from bifactor confirmatory factor analysis (Watkins et al., 2013, Int. J. Sch. Educ. Psychol., 1, 102), indicated that the WISC-IV(UK) FSIQ should retain the greatest weight in WISC-IV(UK) interpretation. © 2014 The British Psychological Society.

  5. News and Views: Very short GRBs may be Hawking radiation source; CubeSat for the UK: UKube1 seeks payloads; Galactic centre? It's just up there… There could be a lot of Earths out there

    Science.gov (United States)

    2010-12-01

    A particular group of gamma-ray bursts, those of very short duration, have characteristics that suggest they may be the signature of an evaporating primordial black hole - the Hawking radiation proposed by Stephen Hawking in 1974. The UK Space Agency is seeking small innovative payloads for the pilot UK CubeSat, UKube1. Planet-hunters have examined the distribution of exoplanets around stars like the Sun in our galaxy, and concluded that they can expect to find planets the size of Earth around a quarter of them - 46 billion or thereabouts.

  6. Construct Validity of the Wechsler Intelligence Scale for Children-Fourth UK Edition with a Referred Irish Sample: Wechsler and Cattell-Horn-Carroll Model Comparisons with 15 Subtests

    Science.gov (United States)

    Canivez, Gary L.; Watkins, Marley W.; Good, Rebecca; James, Kate; James, Trevor

    2017-01-01

    Background: Irish educational psychologists frequently use the Wechsler Intelligence Scale for Children-Fourth UK Edition (WISC-IV[superscript UK]; Wechsler, 2004, Wechsler Intelligence Scale for Children-Fourth UK Edition, London, UK, Harcourt Assessment) in clinical assessments of children with learning difficulties. Unfortunately, reliability…

  7. Knowledge Construction and Personal Relationship: Insights about a UK University Mentoring and Coaching Service

    Science.gov (United States)

    Hargreaves, Eleanore

    2010-01-01

    This article examines interview data from 12 mentors/coaches and eight of their clients in order to explore a mentoring and coaching service among UK university staff. Both mentors/coaches and clients were administrative or academic employees of the Institute of Education or affiliated colleges at London University, UK. Their roles related to the…

  8. Patterns in Payout Policy and Payout Channel Choice of UK Firms in the 1990s

    NARCIS (Netherlands)

    Renneboog, L.D.R.; Trojanowski, G.

    2005-01-01

    The paper examines the payout policy of UK firms listed on the London Stock Exchange during the 1990s.We complement the existing payout literature studies by analyzing jointly the trends in dividends and share repurchases.Unlike in the US, we find that, in the UK, firms do not demonstrate a

  9. Patterns in Payout Policy and Payout Channel Choice of UK Firms in the 1990s

    NARCIS (Netherlands)

    Renneboog, L.D.R.; Trojanowski, G.

    2005-01-01

    The paper examines the payout policy of UK firms listed on the London Stock Exchange during the 1990s.We complement the existing payout literature studies by analyzing jointly the trends in dividends and share repurchases.Unlike in the US, we find that, in the UK, firms do not demonstrate a decreasi

  10. Aircraft observations of the urban CO2 dome in London and calculated daytime CO2 fluxes at the urban-regional scale

    Science.gov (United States)

    Font, Anna; Morgui, Josep Anton; Grimmond, Sue; Barratt, Benjamin

    2013-04-01

    dispersed downwind, with peak concentrations displaced from the urban centre along the main wind direction. The urban-regional surface CO2 flux was calculated for four days in October 2011 by either the Integrative Mass Boundary Layer (IMBL) or the Column Integration method (CIM), dependent on meteorological conditions. The diurnal CO2 flux in London obtained from the aircraft observations ranged from 36 to 71 μmol CO2 m-2 s-1 during the day time. This compared well with continuous measurements of CO2 exchange by an eddy-covariance system located in central London. The day-to-day variability observed in the calculated CO2 fluxes responded to the spatial variability of the influence area and emissions that observations were sensitive to. This study provides an example how aircraft surveys in urban areas can be used to estimate CO2 surface fluxes at the urban-regional scale. It also presents an important cross-validation of two independent measurement-based methods to infer the contribution of urban areas to climate change in terms of CO2 emissions that complement bottom-up emissions inventories. References Committee on Methods for Estimating Greenhouse Gas Emissions (2010), The National Academia Press. DECC (2012), http://www.decc.gov.uk/en/content/cms/statistics/indicators/ni186/ni186.aspx

  11. Market Maker V Automated Order Book Markets: UK Evidence

    OpenAIRE

    Creswell, Phil

    2003-01-01

    The London Stock Exchange operates two separate trading platforms for UK equities: an automated limit order book (SETS) and a multiple dealer market (SEAQ). This paper examines the relative efficiency of the different market structures, by comparing the spread experienced by traders in each market.

  12. Estimation and comparison of night-time OH levels in the UK urban atmosphere using two different analysis methods

    Institute of Scientific and Technical Information of China (English)

    M.Anwar H. Khan; M.M.Nazmul Hoque; S.Shamsul Alam; M.J.Ashfold; Graham Nickless; Dudley E.Shallcross

    2011-01-01

    Night-time OH levels have been determined for UK urban surface environments using two methods, the decay and steady state approximation methods.Measurement data from the UK National Environmental Technology Centre archive for four urban sites (Bristol, Harwell, London Eltham and Edinburgh) over the time period of 1996 to 2000 have been used in this study.Three reactive alkenes, namely isoprene, 1,3-butadiene and trans-2-pentene were chosen for the calculation of OH levels by the decay method.Hourly measurements of NO, NO2, O3, CO and 20 VOCs were used to determine night-time OH level using the steady state approximation method.Our results showed that the night-time OH levels were in the range of 1×105-1×106 molecules/cm3 at these four urbar sites in the UK.The application of a t-test of these analyses indicated that except Bristol, there was no significant difference between the OH levels found from the decay and steady state approximation methods.Night-time levels of the OH radical appeared to peak in summer and spring time tracking the night-time O3 levels which also passed through a maximum at this time.

  13. UK photonics in defence and security

    Science.gov (United States)

    Gracie, C.; Tooley, I.; Wilson, A.

    2008-10-01

    The UK is globally recognised as strong in Photonics. However its Photonics sector is fragmented and the size and sectors of interest have not previously been established. The UK government has instigated the formation of the Photonics Knowledge Transfer Network (PKTN) to bring the Photonics community together. The UK features in Defence & Security; Communications; Measurement; Medical Technology; Lighting; Solar Energy; Information Technology and Flat Panels. This expertise is scattered through out the UK in geographic areas each with a breadth of Photonic interests. The PKTN has mapped the UK capability in all Photonics sectors. This paper will present the capability of the Companies, Research Institutions and Infrastructure making up the Defence & Security Photonics scene in the UK. Large Defence companies in the UK are well known throughout the world. However, there are a large number of SMEs, which may not be as well known in the supply chain. These are being actively encouraged by the UK MoD to engage with the Defence & Security Market and shall be discussed here. The presentation will reference a number of organisations which help to fund and network the community, such as the Defence Technology Centres. In addition the Roadmap for Defence & Security in the UK, produced for the UK Photonics Strategy (July 2006) by the Scottish Optoelectronics Association will be described and the plans in taking it forward under the PKTN will be revealed.

  14. Transmitted antiretroviral drug resistance in treatment naïve HIV-infected persons in London in 2011 to 2013

    Directory of Open Access Journals (Sweden)

    Katie McFaul

    2014-11-01

    Full Text Available Introduction: Previously published UK data on HIV transmitted drug resistance (TDR shows that it ranges between 3 and 9.4% [1,2]. However, there are no recent data from populations where HIV transmission rates are increasing. The aim of this study was to assess the prevalence of TDR in untreated HIV-infected individuals attending three HIV specialist clinics under the HIV Directorate, Chelsea and Westminster Hospital and based throughout London – the Kobler Clinic, 56 Dean Street and West London Centre for Sexual Health. Methods: We included all patients with a HIV diagnosis, no history of antiretroviral therapy (ART intake, attending one of the three clinics (Kobler (K, 56 Dean Street (DS and West London (WL, between 2011 and 2013 who started antiretrovirals. Reverse transcriptase (RT and protease region sequencing was performed using Vircotype virtual phenotype resistance analysis. Drug resistance mutations were identified according to Stanford University HIV Drug Resistance Database (http://hivdb.stanford.edu/. Results: Among 1705 HIV-1-infected patients enrolled in the study, 1252 were males (919 were MSM, 107 were females and 346 had no gender recorded. Ethnicity was 51.1% white British/Irish/other, 6.1% African, 2.1% Caribbean, 2.8% Asian, 1.3% Indian/Pakistani/Bangladeshi, 4.2%, other, 3.2% not stated, and 29.2% unknown. 547 were from K (84.3% males, 48.3% MSM, 826 were from DS (84.3% males, 71.9% MSM, and 109 from WL (87.2% males, 56.0% MSM, 223 from other sites not specified. 77.5% (1321 of 1705 of patients had baseline viral resistance testing performed. Prevalence of primary resistance in those with a baseline viral resistance test was 13.5% overall: 19.3% in K, 14.9% in DS, and 14.7% in WL. The most common mutations detected were: NRTI: 184V, 215F, 41L; NNRTI 103N, 179D, 90I; PI 90M, 46I, and 82A. Among patients who tested with TDR, 79.1% had one single mutation, 18.7% and 2.2% exhibited dual or triple class-resistant viruses

  15. Sao Paulo city and London architectonic epigraphs: a comparison from an information design perspective

    Directory of Open Access Journals (Sweden)

    Priscila Lena Farias

    2016-03-01

    Full Text Available This paper presents a comparative study on inscriptions containing the names of architects and builders found in the façades of building in the cities of São Paulo and London. For the study, 123 architectonic epigraphs found in São Paulo city historic centre were compared with 71 inscriptions of the same kind found in the regions of Westminster and Camden, in central London. The focus of the analysis is the informational aspects of the inscriptions, including its location, size, typographic configuration and content.

  16. UK Renal Registry 18th Annual Report: Chapter 11 2014 Multisite Dialysis Access Audit in England, Northern Ireland and Wales and 2013 PD One Year Follow-up: National and Centre-specific Analyses.

    Science.gov (United States)

    Rao, Anirudh; Evans, Rebecca; Wilkie, Martin; Fluck, Richard; Kumwenda, Mick

    2016-01-01

    Data are presented from the third combined vascular and peritoneal dialysis access audit. In 2014, 53 centres in England, Wales and Northern Ireland (out of 62) returned data on first access from 4,339 incident haemodialysis (HD) patients and 1,090 incident peritoneal dialysis (PD) patients. Of the 5,429 incident patients, 20.1% started dialysis on PD, 27.8% started with an arteriovenous fistula (AVF), 1.0% with an arteriovenous graft (AVG), 27.1% on a tunnelled line (TL) and 24.0% on a non-tunnelled line (NTL). Older patients (565 years) were more likely to start haemodialysis using AVF compared to their younger counterparts (36.2% vs. 32.8%). Thirteen of the nineteen centres (68%) using the physician led percutaneous insertion technique had over 20% of their incident patients starting on PD when compared to only seven out of fourteen centres (50%) which used single technique (open surgical or laparoscopic) for their PD catheter insertion. Wide variations were apparent between centres for use of AVF as the first haemodialysis access ranging from 10–54%. Eight of the 49 centres were achieving close to the 65% target for AV fistula in their incident patients. Length of time known to nephrology services and likelihood of commencing dialysis using either an AVF or a PD catheter are strongly associated. Patients who were known to a nephrologist for over one year were more likely to start dialysis with AVF, as compared to those who were referred between 90–365 days (39.2% vs. 24.6%). Similarly, patients who were known to a nephrologist between 90 days and one year were more likely to start on PD when compared to patients who were referred dialysis start (26.9% vs. 9.1%). By comparison, amongst the late presenters, only 3.5% had first access documented as an AVF and 87.3% started dialysis on either a tunnelled line or a non-tunnelled line. Initial surgical assessment was a key determinant of the likelihood of AVF formation. Of the incident patients known to renal

  17. Bringing together values-based and evidence-based medicine: UK Department of Health Initiatives in the 'Personalization' of Care.

    Science.gov (United States)

    Fulford, K W M Bill

    2011-04-01

    Person-centred medicine depends on combining best research evidence with the unique values (including the preferences, concerns, needs and wishes) of individual patients and their families. The paper gives a brief introduction to values-based practice as a new approach to incorporating patients' values into clinical decision making alongside best research evidence as derived from evidence-based practice. The role of values-based practice as a partner to evidence-based practice is illustrated through a series of policy, training and service development initiatives in mental health from the UK Department of Health in London. These initiatives have supported person-centred developments in key areas of mental health practice including, (1) the use of involuntary treatment; and (2) a shared approach of assessment. Early moves are underway to extend values-based practice to other areas of health care beyond mental health. Values-based practice offers a new approach to incorporating patients' unique values into clinical decision making that is complementary to evidence-based practice as a resource for person-centred medicine. © 2010 Blackwell Publishing Ltd.

  18. ATLAS Virtual Visit London-20-08-2014

    CERN Multimedia

    2014-01-01

    Working at the highest energy particle accelerator in the world, a group of scientists gathers each year to discuss the science and discovery potential of extremely energetic and complex phenomena that might emerge from the proton collisions at the LHC. The BOOST Conference of 2014 is hosted by the UCL HEP Group at the heart of London, and features an evening of particle physics, including an introduction to the Higgs and the Large Hadron Collider, a virtual visit to CERN hosted by David Miller of Chicago University, a talk by TEDx speaker Lily Asquith (Argonne National Lab/Sussex Uni) on sonification of LHC data, and a question and answer session! More information can be found on the conference website at: http://www.hep.ucl.ac.uk/boost2014/.

  19. Optimum design methodologies for pile foundations in London

    Directory of Open Access Journals (Sweden)

    Christos Letsios

    2014-12-01

    Full Text Available Given the importance of pile foundations in geotechnical engineering for supporting high-significance structures such as bridges, high-rise buildings, power plant stations, offshore platforms and museums, it becomes a necessity to find the best pile foundation design in terms of performance and economy. The number of piles required might exceed several hundreds or even thousands while the pile foundation cost might exceed 20% of the construction cost of the superstructure. In this work the problem of finding optimized designs of pile foundations is examined and is performed in accordance to two design code recommendations, namely Eurocode 7 and DIN 4014. The proposed structural optimization procedure is implemented in two real-world cases both located in London, UK in order to assess the efficiency of the proposed design formulation.

  20. International Workshop on Glasses and Ceramics, Hybrids and Nanocomposites from Gels (9th); Sol-Gel 󈨥 Held in Centre for Glass Research, The University of Sheffield, UK on 31 August-5 September 1997

    Science.gov (United States)

    1998-01-01

    5581), Universite Montpellier II, F-34095 Montpellier Cedex 5 lionel@gdpc.univ-montp2.fr T. GULIK-KRZYWICKI Centre de Genetique Moleculaire-CNRS...hydrolysis and gelation can be manipulated separately. Compared with aqueous sys- tems, borosiloxanes formed in this anhydrous system References 1. H...molecular weight of the organic polymers, as well as temperature; a precise control of viscosity can usually be attained by manipulating these

  1. Tracer concentration profiles measured in central London as part of the REPARTEE campaign

    Directory of Open Access Journals (Sweden)

    D. E. Shallcross

    2009-11-01

    Full Text Available There have been relatively few tracer experiments carried out that have looked at vertical plume spread in urban areas. In this paper we present results from cyclic perfluorocarbon tracer experiments carried out in 2006 and 2007 in central London centred on the BT Tower as part of the REPARTEE (Regent's Park and Tower Environmental Experiment campaign. The height of the tower gives a unique opportunity to study dispersion over a large vertical gradient. These gradients are then compared with classical Gaussian profiles of the relevant stability classes over a range of distances as well as interpretation of data with reference to both anemometry and LIDAR measurements made. Data are then compared with an operational model and contrasted with data taken in central London as part of the DAPPLE campaign looking at dosage compared with non-dimensionalised distance from source. Such analysis illustrates the feasibility of the use of these empirical correlations over these prescribed distances in central London.

  2. Ethnopharmacy of Turkish-speaking Cypriots in Greater London.

    Science.gov (United States)

    Yöney, Ahmet; Prieto, José M; Lardos, Andreas; Heinrich, Michael

    2010-05-01

    For centuries, in the Eastern Mediterranean region, medicinal plant use has been widely accepted as a treatment method for both minor and major diseases. Although some knowledge exists on the use of such medicinal plants within the Greek Cypriot culture and considerable information is available on various regions in Turkey, no detailed ethnopharmaceutical or ethnobotanical studies exist on Turkish-speaking Cypriots (TSC) both in Cyprus and within one of the largest TSC migrant communities in London, UK. Semi-structured interviews with members of the TSC community in London were conducted by using a questionnaire consisting both of open and closed questions. Open questions were aimed at identifying herbs, spices, medicinal plants and their uses. Also, graded questions were used to define informants' opinions as a quantitative parameter, constructing a statistical basis. A wide range of therapeutic claims were recorded, including 13 chronic illnesses within 85 different plant species, of which 18 were cited more than 10 times. The most frequently mentioned species were Mentha spicata, Salvia fruticosa and Pimpinella anisum. The plants recorded are frequently based on knowledge derived from Turkish-Cypriot traditions, but many examples of medicinal plants with a use based on UK or general western herbal medical traditions were also recorded. Informants highlighted the risk of knowledge loss in younger generations and thus this study serves as a repository of knowledge for use in the future. Due to a lack of knowledge about such usages in the healthcare professions, our study also highlights the need to develop information sources for use by healthcare practitioners in order to raise awareness about benefits and risks of such medical and health food products.

  3. Person-centred reflective practice.

    Science.gov (United States)

    Devenny, Bob; Duffy, Kathleen

    Person-centred health and person-centred care have gained prominence across the UK following the publication of reports on public inquiries exploring failings in care. Self-awareness and participation in reflective practice are recognised as vital to supporting the person-centred agenda. This article presents an education framework for reflective practice, developed and used in one NHS board in Scotland, and based on the tenets of the clinical pastoral education movement. Providing an insight into the usefulness of a spiritual component in the reflective process, the framework provides an opportunity for nurses and other healthcare professionals to examine the spiritual dimensions of patient encounters, their own values and beliefs, and the effect these may have on their practice.

  4. Taking centre stage...

    Science.gov (United States)

    1998-11-01

    Millennium Dome site, constructing a model of the Dome and designing a range of Dome exhibits from innovative assembly kits. Details of the 1999 competition will be available from the Engineering Council at 10 Maltravers Street, London WC2R 3ER (tel: 0171 240 7891, http://www.engc.org.uk).

  5. Clinical epidemiology of epithelial ovarian cancer in the UK

    Directory of Open Access Journals (Sweden)

    Doufekas K

    2014-05-01

    Full Text Available Konstantinos Doufekas, Adeola OlaitanDepartment of Gynaecological Oncology, University College London Hospitals, London, UKAbstract: Epithelial ovarian cancer is the fifth commonest cancer among women and the leading cause of gynecological cancer death in the UK. Most women present with advanced disease, mainly because the nonspecific nature of the symptoms lead to diagnostic delays. Recent data have shown a fall in ovarian cancer mortality rates in the UK, but rates are still higher when compared to other European countries or the USA. In addition, surgeons in the UK achieve on average lower optimal surgical cytoreduction rates in patients with advanced ovarian cancer. Despite a wealth of information on epidemiological risk factors, the pathogenesis of epithelial ovarian cancer remains largely unknown. This review presents the most recent data on incidence, mortality, and survival for epithelial ovarian cancer in the UK. Time trends, trends by age, international comparisons, and regional variation in incidence, survival, and mortality are presented within the context of a major reorganization of cancer services that took place in the UK over 10 years ago. Centralization of cancer services has meant that women with ovarian cancer receive treatment in specialist Cancer Centers.Keywords: ovarian, cancer, epidemiology, UK, incidence, survival

  6. Central and East European migrant men who have sex with men in London: a comparison of recruitment methods

    Directory of Open Access Journals (Sweden)

    Gerry Christopher J

    2011-05-01

    Full Text Available Abstract Background Following the expansion of the European Union, there has been a large influx of Central and East European (CEE migrants to the UK. CEE men who have sex with men (MSM represent a small minority within this population that are none-the-less important to capture in sexual health research among the CEE migrant community. This paper examines the feasibility of recruiting CEE MSM for a survey of sexual behaviour in London using respondent driven sampling (RDS, via gay websites and in GUM clinics. Methods We sought CEE MSM to start RDS chain referral among GUM clinic attendees, our personal contacts and at gay events and venues in central London. We recruited CEE MSM (n = 485 via two popular websites for gay men in Britain (March-May 2009 and at two central London GUM clinics (n = 51 (July 2008-March 2009. Results We found seventeen men who knew other CEE MSM in London and agreed to recruit contacts into the study. These men recruited only three men into the study, none of whom recruited any further respondents, and RDS was abandoned after 7 months (July 2008-January 2009. Half of the men that we approached to participate in RDS did not know any other CEE MSM in London. Men who agreed to recruit contacts for RDS were rather more likely to have been in the UK for more than one year (94.1% vs 70.0%, p = 0.052. Men recruited through gay websites and from GUM clinics were similar. Conclusions The Internet was the most successful method for collecting data on sexual risk behaviour among CEE MSM in London. CEE MSM in London were not well networked. RDS may also have failed because they did not fully understand the procedure and/or the financial incentive was not sufficient motivation to take part.

  7. A Migrant Culture on Display: The French Migrant and French Gastronomy in London (19th – 21st centuries)

    OpenAIRE

    Kelly, D.

    2016-01-01

    The large contemporary French migrant population – estimated by the French Consulate at around 300,000–400,000 in the UK, the majority living in London and the South-East – remains ‘absent’ from studies on migration, and, in a study of migrant food history in Britain, is considered not to have left traces as a migrant community. Over the centuries, the presence of various French communities in London has varied significantly as far as numbers are concerned, but what does not change is their s...

  8. Modelling total energy costs of sports centres

    Energy Technology Data Exchange (ETDEWEB)

    Boussabaine, A.H.; Kirkham, R.J.; Grew, R.J. [Liverpool Univ., School of Architecture and Building Engineering, Liverpool (United Kingdom)

    1999-12-07

    Providing and maintaining safe and comfortable conditions in sport centres raises many issues, particularly cost. The paper gives an overview of the factors associated with sport centre servicing and attempts to highlight the governing factors associated with this, particularly energy costs. A total of 19 sport centres in the City of Liverpool in the UK are investigated, using data elicited from the Liverpool Leisure Services Directorate. The energy operating costs were analysed using statistical methods. Six models were developed to predict total energy costs. Testing and validation results showed a high level of model accuracy. The models would be of use to professionals involved in feasibility studies at the design stage. (Author)

  9. Mind the gap: financial London and the regional class pay gap.

    Science.gov (United States)

    Friedman, Sam; Laurison, Daniel

    2017-09-01

    The hidden barriers, or 'gender pay gap', preventing women from earning equivalent incomes to men is well documented. Yet recent research has uncovered that, in Britain, there is also a comparable class-origin pay gap in higher professional and managerial occupations. So far this analysis has only been conducted at the national level and it is not known whether there are regional differences within the UK. This paper uses pooled data from the 2014 and 2015 Labour Force Survey (N = 7,534) to stage a more spatially sensitive analysis that examines regional variation in the class pay gap. We find that this 'class ceiling' is not evenly spatially distributed. Instead it is particularly marked in Central London, where those in high-status occupations who are from working-class backgrounds earn, on average, £10,660 less per year than those whose parents were in higher professional and managerial employment. Finally, we inspect the Capital further to reveal that the class pay gap is largest within Central London's banking and finance sector. Challenging policy conceptions of London as the 'engine room' of social mobility, these findings suggest that class disadvantage within high-status occupations is particularly acute in the Capital. The findings also underline the value of investigating regional differences in social mobility, and demonstrate how such analysis can unravel important and previously unrecognized spatial dimensions of class inequality. © London School of Economics and Political Science 2017.

  10. The Influence of Green Infrastructure on Urban Resilience in Greater London

    Science.gov (United States)

    Oh, Yukyung

    2017-04-01

    High population densities and diverse economic activities in urban areas create social issues as well as a range of environmental impacts including air pollution, soil contamination, loss of biodiversity and health problems (Alberti et al., 2003; Dobbs, Escobedo, & Zipperer, 2011; Grimm et al., 2008). The concept of urban resilience has been used for increasing the capacity of the entities and players to adapt to rapid changes, and urban green spaces play a crucial role in increasing urban resilience. Greater London has a good case for increasing urban green spaces and resilience under the London Plan. The relevance of urban open spaces and several socioeconomic indicators would provide researchers and policy makers with the information for managing green coverage. The correlation analysis of two quantitative data such as open space and socioeconomic data of Greater London was conducted with SPSS. The data for open spaces in Greater London was gained through Greenspace Information for Greater London. The data was converted from vector to raster in Geographic Information System (GIS), so as to calculate landscape metrics for open spaces in Greater London through a spatial pattern analysis program, FRAGSTATS 4.2. The socioeconomic data was obtained from "London Borough Profile", London Datastore. In addition, data on total carbon emissions from Industry and Commercial, Domestic, Transport, LULUCF Net Emissions, and per capita emissions were gained from UK local authority and regional carbon dioxide emissions national statistics: 2005-2014 released from Department of Energy and Climate Change. The indicators from open spaces are total area of open space and patch density or contagion of open spaces. The latter indicator allows to figure out the level of fragmentation of open spaces. The socioeconomic indicators cover number of jobs by workplace, jobs density, crime rates per thousand population, and several wellbeing indicators such as life satisfaction

  11. eSDO algorithms, data centre and visualization tools

    Science.gov (United States)

    Auden, E.; Toutain, T.; Zharkov, S.

    2007-03-01

    The eSDO project is a UK e-Science project funded by PPARC to develop solar algorithms, visualization tools and designs for a UK data centre that can be accessed through the UK virtual observatory in preparation for the Solar Dynamic Observatory (SDO) mission in 2008. Algorithms available for use by the solar community include helioseismology applications, coronal feature recognition, and wave power analysis. Visualization tools will allow users to vary time ranges, cadence and resolution and they view streams of images data from the Atmospheric Imaging Assembly (AIA) and Helioseismic Magnetic Imager (HMI) instruments. Finally, a prototype UK data centre will demonstrate efficient UK user access to SDO data through both AstroGrid searches and integration with the global SDO data archive.

  12. What factors influence UK medical students’ choice of foundation school?

    Directory of Open Access Journals (Sweden)

    Miah S

    2017-04-01

    Full Text Available Saiful Miah,1,2 Karl H Pang,3 Wayne Rebello,4 Zoe Rubakumar,4 Victoria Fung,5 Suresh Venugopal,6 Hena Begum4 1Division of Surgery and Interventional science, University College London, London, UK; 2Department of Urology, Charing Cross Hospital Imperial College Healthcare NHS Trust, London, UK; 3Academic Urology Unit, University of Sheffield, Sheffield, UK; 4Medical School, University of Sheffield, Sheffield, UK; 5Department of Plastic Surgery, Royal Hallamshire Hospital, Sheffield, UK; 6Department of Urology, Chesterfield Royal Infirmary, Chesterfield, UK Background: We aimed to identify the factors influencing UK medical student applicants’ choice of foundation school. We also explored the factors that doctors currently approaching the end of their 2-year program believe should be considered. Methods: A cross-sectional study was conducted during the 2013–2014 academic year. An online questionnaire was distributed to 2092 final-year medical students from nine UK medical schools and 84 foundation year-2 (FY2 doctors from eight foundation schools. Participants were asked to rank their top 3 from a list of 12 factors that could potentially influence choice of foundation school on a 5-point Likert scale. Collated categorical data from the two groups were compared using a chi-square test with Yates correction. Results: Geographic location was overwhelmingly the most important factor for medical students and FY2 doctors with 97.2% and 98.8% in agreement, respectively. Social relationships played a pivotal role for medical student applicants. Clinical specialties within the rotations were of less importance to medical students, in comparison to location and social relationships. In contrast, FY2 doctors placed a significantly greater importance on the specialties undertaken in their 2-year training program, when compared to medical students (chi-square; p=0.0001. Conclusion: UK medical schools should make their foundation program applicants aware

  13. Proceedings of the Seventh International Conference on Educational Data Mining (EDM) (7th, London, United Kingdom, July 4-7, 2014)

    Science.gov (United States)

    Stamper, John, Ed.; Pardos, Zachary, Ed.; Mavrikis, Manolis, Ed.; McLaren, Bruce M., Ed.

    2014-01-01

    The 7th International Conference on Education Data Mining held on July 4th-7th, 2014, at the Institute of Education, London, UK is the leading international forum for high-quality research that mines large data sets in order to answer educational research questions that shed light on the learning process. These data sets may come from the traces…

  14. The Dutch and British public debate on Islam: responses to the killing of Theo van Gogh and the London bombings compared

    NARCIS (Netherlands)

    Vellenga, S.

    2008-01-01

    Since the beginning of this century, Islam has become the subject of an intensive debate within Europe. Major triggers of this debate were, in the Netherlands, the assassination of the filmmaker Theo van Gogh on 2 November 2004 and, in the UK, the London bombings on 7 July 2005. Both violent actions

  15. The UK Casting Industry

    Institute of Scientific and Technical Information of China (English)

    Jincheng Liu

    2006-01-01

    The casting production in the UK in 2004 is presented and analysed. The UK casting industry has played an important role in world casting and manufacturing production. However recent years the rapid development of some developing countries has been shifting the casting production from the western industrialized countries including the UK. The UK casting industry and associated research and technology organizations, universities have been working together very hard to face the serious competition to make the UK casting industry have a sustainable future. The UK casting industry remains strong and plays an important role in world casting and manufacturing production.

  16. The Imperial College Thermophysical Properties Data Centre

    Science.gov (United States)

    Angus, S.; Cole, W. A.; Craven, R.; de Reuck, K. M.; Trengove, R. D.; Wakeham, W. A.

    1986-07-01

    The IUPAC Thermodynamic Tables Project Centre in London has at its disposal considerable expertise on the production and utilization of high-accuracy equations of state which represent the thermodynamic properties of substances. For some years they have been content to propagate this information by the traditional method of book production, but the increasing use of the computer in industry for process design has shown that an additional method was needed. The setting up of the IUPAC Transport Properties Project Centre, also at Imperial College, whose products would also be in demand by industry, afforded the occasion for a new look at the problem. The solution has been to set up the Imperial College Thermophysical Properties Data Centre, which embraces the two IUPAC Project Centres, and for it to establish a link with the existing Physical Properties Data Service of the Institution of Chemical Engineers, thus providing for the dissemination of the available information without involving the Centres in problems such as those of marketing and advertising. This paper outlines the activities of the Centres and discusses the problems in bringing their products to the attention of industry in suitable form.

  17. Alcohol Gel Ingestion Among Homeless Eastern and Central Europeans in London: Assessing the Effects on Cognitive Functioning and Psychological Health

    OpenAIRE

    Dawkins, LE; Soar, K; Papaioannou, G.

    2016-01-01

    Background: Intentional consumption of alcohol based hand gels has been reported especially amongst non-UK national, alcohol dependent, homeless individuals in London. Whilst alcohol misuse is known to be associated with impaired cognitive functioning and mental health problems, the effects of additional ingestion of alcohol gel are unknown. Objectives: To explore cognitive and psychological functioning in users who intentionally ingest alcohol gel compared with ethyl-alcohol only misusers an...

  18. Assessing the sources and bioaccessibility of Lead in Soils from London

    Science.gov (United States)

    Cave, Mark R.; Wragg, Joanna; Chenery, Simon

    2013-04-01

    The lead content of soil is important since it is toxic to humans and particularly because children tend to more readily absorb lead than do adults: children absorb up to 40% into the bloodstream from ingested or inhaled lead, versus 5-15% in adults. Studies have shown that relatively low concentrations of lead in blood can lead to significant decrease in IQ of children (e.g. Jakubowski, 2011) leading to neuropathy and hypertension in adults. The British Geological Survey has recently completed a systematic high-density geochemical soil survey of the Greater London Area (GLA) in which over 6000 surface soil samples were collected and analysed for 50 elements. The Pb content of the soils range from 11 mg/kg to greater than 10000 mg/kg with mean and median values of 301 and 185 mg/kg, respectively. The ingestion bioaccessible fraction of Pb was measured using an in-vitro bioaccessibility test showing that 68% of the total Pb in London soils is bioaccessible. Measurement of Pb isotopic ratios in selected soils matched with those found in London air particulates and, to a lesser extent, with petrol lead. Self modelling mixture resolution of the 50 element geochemical data set was used to identify geochemically distinct components in the data with Pb being associated with 11 of the components which were of both natural and anthropogenic origin. Relationships between the soil components, the bioaccessible fraction and the Pb isotope ratios provided an indication of the sources of mobile lead in the London soils. References JAKUBOWSKI, M. 2011. Low-level environmental lead exposure and intellectual impairment in children - the current concepts of risk assessment. International Journal of Occupational Medicine and Environmental Health, Vol. 24, 1-7. APPLETON, J D, CAVE, M R, and WRAGG, J. 2012. Modelling lead bioaccessibility in urban topsoils based on data from Glasgow, London, Northampton and Swansea, UK. Environmental Pollution, Vol. 171, 265-272.

  19. An update on UK rheumatology consultant workforce provision: the BSR/ARC Workforce Register 2005–07: assessing the impact of recent changes in NHS provision

    Science.gov (United States)

    Harrison, M. J.; Deighton, C.

    2008-01-01

    Objectives. To describe changes in the provision of rheumatology services, monitor the pattern of inequalities in UK rheumatology service provision since 2005, and to summarize the 3-yr impact of the new National Health Service (NHS) consultant contract and the Musculoskeletal Services Framework in England and Wales. Methods. Questionnaires about timetable and working conditions were sent to all consultants on the BSR/ARC UK Workforce Register in January 2007, along with the personal and job-related details currently held about them on the register to update. The questionnaire included a visual analogue scale asking ‘how concerned are you that your current post might be under threat’ ranging from 0 ‘Not at all’ to 100 ‘Extremely’. Results. The response rate of the 2005 and 2007 surveys were 89 and 87%, respectively. Levels of optimal provision now exceed 70% in England and Wales, and 50% in Scotland and Northern Ireland. Levels of provision remain substantially higher in London than anywhere else. The median level of perceived job threat in the UK was 31 (interquartile range 11–61). Consultants in areas where provision is highest and a higher proportion of services are run in conjunction with Clinical Assessment and Treatment (CAT) centres report higher perceived job threat. Conclusions. Provision of rheumatology services has continued to expand over the past decade; however, inequalities persist at national and sub-national level. There is evidence of improvement in regions with the lowest provision, but there are indications of increased perceived job threat in areas with traditionally higher provision and where CAT centres have been introduced. PMID:18424468

  20. Accounting for Impact at Imperial College London

    DEFF Research Database (Denmark)

    Perkmann, Markus; Fini, Riccardo; Ross, Jan-Michael

    We report findings of a study of academic engagement and commercialisation at Imperial College London. We detail the extent of collaboration with industry, consulting, patenting and entrepreneurship by Imperial academics, as well as individuals’ motivations and perceived barriers to engagement. T...

  1. Movement and Character. Lecture, London, 1946

    Science.gov (United States)

    Montesorri, Maria

    2013-01-01

    Dr. Montessori's words from the 1946 London Lectures describe principles of intelligence and character, the work of the hand, and movement with a purpose as being integral to self-construction. The perfection of movement is spiritual, says Dr. Montessori. Repetition of practical life exercises are exercises in movement with the dignity of human…

  2. Staging the orient. Aladdin London - Copenhagen

    DEFF Research Database (Denmark)

    Svane, Marie-Louise

    2017-01-01

    En sammenligning af John O'Keefes / Charles Farleys sceniske opsætning af Aladdin-eventyret fra Tusind og én nats eventyr i London (1813) med Adam Oehlenschlägers Aladdin-lystspil i København (1805). Artiklen diskuterer de to versioner af eventyrstykket som fortolkning og respons på to forskellig...

  3. Loss and material culture in South London

    NARCIS (Netherlands)

    Miller, D.; Parrott, F.

    2009-01-01

    This article describes the ways in which people, mainly selected from a single street in South London, utilize material culture in dealing with various experiences of separation and loss, such as death or the ending of a relationship. It starts from a dialectical approach to all relationships as con

  4. E. B. Nicholson and the London Institution

    Science.gov (United States)

    Manley, K. A.

    1973-01-01

    This article provides a history of the London Institution from 1805 to 1912, with special emphasis on E. B. Nicholson's term of office. The last years of the Institution are considered, its financial difficulties being traced back to the terms of its original foundation, and to the changing situation of its members. (47 references) (Author/SJ)

  5. Comparison and assessment of the participation of Polish swimmers at the Olympic and Paralympic Games in London

    Directory of Open Access Journals (Sweden)

    Seidel Wojciech

    2014-05-01

    Full Text Available Purpose : to assess and analyze the results of the Polish national team swimmers (Olympic and Paralympic at the XIV Summer Games 2012 in London (UK . Material : Score Polish swimmers start in London was carried out on the basis of medals won, participation in the finals. London also comparing the results with respect to the personal life record. The studies used the method of improving the outcome of the relative percentages - RPG% (relative performance gain %. It is based on the equation of RPG% = start time - end time / start time x 100. Material was to analyze and develop the results obtained by the Polish swimmers at the XIV Olympic and Paralympic Games in 2012 in London. Results : the basic criterion for evaluating the training and participation of Polish swimmers at the games in London was the number of medals won. By this criterion, the Poles showed a rather weak result. Healthy athletes do not receive medals. Thus, they confirmed their poor showing four years ago. Athletes with disabilities unable to get on the podium three times. In relation to the previous games (they won 10 medals the result was rather weak. Conclusions : in terms of participation in the Olympic finals and improve individual life records, the results were slightly better swimmers with disabilities.

  6. Skyscraper indicator and its application in the UK

    Directory of Open Access Journals (Sweden)

    Arvydas Jadevicius

    2016-06-01

    Full Text Available Objective: The research examines Skyscraper Indicator and its application in the UK. Until more recently, it was thought that this indicator was not suitable in gaging trajectory of Britain’s economy. The current study is therefore set to investigate whether Skyscraper Indicator can be used as a potential leading indicator for the UK. Research Design & Methods: Research employs dummy variable regression to test the hypothesis. The study selects quarterly UK GDP and GDP per capita series over Q1 1960 - Q4 2014 period as macro variables and a series of dummies for construction starts, durations and completions of the record-breaking buildings in the UK. Findings: Despite some of the methodological limitations, estimates suggest that the announcement of the construction of tallest building in the UK is related to national GDP. Implications & Recommendations: To make robust economic forecasts, analysts may therefore use the announcement of the construction of the record breaking skyscraper as a possible bell-weather in gaging future direction of the UK economy. They may turn their gaze towards the London skyline when contemplating UK market movements. Contribution & Value Added: The paper adds additional evidence on the contested Skyscraper Indicator issue.

  7. Survey of community pharmacists' perception of electronic cigarettes in London

    Science.gov (United States)

    Marques Gomes, Ana C N; Nabhani-Gebara, Shereen; Kayyali, Reem; Buonocore, Federico; Calabrese, Gianpiero

    2016-01-01

    Objectives To seek community pharmacists' perception on use, safety and possible effectiveness of e-cigarettes as quit smoking tools, and their future regulation. Setting A survey of a sample of 154 community pharmacies across London, UK. Context E-cigarettes have exclusively established themselves in the market through consumers-led demand. To date, e-cigarettes still remain unregulated and can be easily purchased in shops, over the internet, but more controversially also in pharmacies in the UK. Pharmacists find themselves with a shortage of information on their safety and efficacy, and may experience an ethical dilemma when consulted by patients/customers. Key findings Response rate: 60% (n=92). Independent pharmacies accounted for 90% of the sample. The majority of participants (73%) sell e-cigarettes. A minority of participants (20%) have been presented with adverse effects such as cough and dry mouth. As possible reasons for their use, pharmacists ranked ‘aid in stop smoking’ as the most important (56%), with ‘cheaper alternative’ (43%) and ‘social/recreational use’ (31%) being the least important ones. Safety issues were raised as statements such as ‘e-liquid in cartridges may be toxic’ were agreed by 52% of respondents. The majority of pharmacists (97%) were supportive of e-cigarettes being regulated, expressing current concerns regarding excipients (42%) and nicotine content (34%). Participants indicated that they would require training in the form of information packs (88%), online tutorials (67%), continuous professional development (CPD) workshops (43%) to cover safety, counselling, dosage instructions, adverse effects and role in the smoking cessation care pathway in the future. Conclusions Pharmacists expressed concerns about the safety of e-cigarettes, especially regarding the amounts of excipients and nicotine as these still remain unregulated. Currently, there are no guidelines for pharmacists regarding e-cigarettes. Community

  8. The state of ocular health among London's homeless population.

    Science.gov (United States)

    Sawers, N

    2017-04-01

    PurposeTo investigate the demographics, visual impairment, and diagnoses of patients presenting to Vision Care for Homeless People (VCHP), Crisis clinics for London's under-researched homeless population.Patients and methodsTwo hundred eighty-three patients records, including data on sociodemographic, diabetic status, visual acuity, and ocular examination, via a comprehensive eye test were reviewed from the VCHP clinics held at 10 London 'Crisis at Christmas' centres in 2014.ResultsTwo hundred eighty-three individual patients were seen at the VCHP clinics. Eighty-nine percent of patients were male and 11% were female. Thirty-two percent (90) patients had an ocular pathology. Lens problems, including cataracts (7%), vitreoretinal (6%), ocular motility (5%), and external eye disease (5%), were the four most common pathologies. In total, 6.4% of the patients reported that they were diabetic and a medical referral letter was given to 10% of the patients seen. Two hundred thirty-three were dispensed glasses (82%). Readers were most common (39%), then distance (28%), bifocals (15%). Presenting visual impairment was 12% in the patients tested. After refractive correction, this dropped to 2.5%.ConclusionThis study shows that there is a high prevalence of uncorrected refractive error among patients attending the Crisis for Christmas eye clinic. These data also show high prevalence of ocular pathology. There is a clear need for the provision of eye tests and spectacles to tackle the issues and prevent visual impairment. More research and eye care services are needed to investigate how this is linked to their living status and enable this vulnerable population to transition out of homelessness.

  9. Integrating Regional Development, Promoting Local Cooperation Reflections on the China-UK Regional Leaders Exchange Program

    Institute of Scientific and Technical Information of China (English)

    Liu; Chang

    2016-01-01

    The first China-UK Regional Leaders Meeting was held March21-24 in the United Kingdom,both in London and the industrial city of Sheffield.The event was jointly organized by the CPAFFC and the British Department for Communities and Local Government.The Chinese delegation,comprising government

  10. Supporting a UK Success Story: The Impact of University Research and Sport Development

    Science.gov (United States)

    Universities UK, 2012

    2012-01-01

    As part of an Olympic and Paralympic themed Universities Week this new report highlights just some of the many ways in which research will help Team Great Britain achieve exceptional results. While most attention will be on the results achieved in London this summer, it is inspiring to look at the research taking place in UK universities that will…

  11. Listening to those on the frontline: service users' experiences of London tuberculosis services

    Directory of Open Access Journals (Sweden)

    Boudioni M

    2011-06-01

    Full Text Available Markella Boudioni, Susan McLaren, Ruth Belling, Leslie WoodsInstitute for Leadership and Service Improvement, Faculty of Health and Social Care, London South Bank University, London, UKAim: To explore tuberculosis (TB service users' experiences and satisfaction with care provision.Background: Thirty-nine percent of all new UK TB cases occur in London. Prevalence varies considerably between and within boroughs. Overall, research suggests inadequate control of London's TB transmission; TB has become a health care priority for all London Primary Care Trusts. Service users' experiences and satisfaction with care provision have not been explored adequately previously.Methods: A qualitative research design, using semi-structured face-to-face interviews was used. Ten service users, purposively selected in key risk groups across London, were interviewed. All interviews were digitally recorded with users' permission, transcribed verbatim, and analyzed thematically.Results: Participants were treated in local hospitals for 6–12 months. Treatment was administered by TB nurses to inpatients and outpatients receiving directly observed therapy in consultation with medical staff and home visits for complex cases. Two participants did not realize the importance of compliance. Overall, they were satisfied with many TB services' aspects, communication, and service organization. Early access, low suspicion index amongst some GPs, and restricted referral routes were identified as service barriers. Other improvement areas were information provision on drug side effects, diet, nutritional status, and a few health professionals' attitudes. The effects on people varied enormously from minimal impact to psychological shock; TB also affected social and personal aspects of their life. With regard to further support facilities, some positive views on managed accommodation by TB-aware professionals for those with accommodation problems were identified.Conclusion: This

  12. Uncertainties in Tidally Adjusted Estimates of Sea Level Rise Flooding (Bathtub Model for the Greater London

    Directory of Open Access Journals (Sweden)

    Ali P. Yunus

    2016-04-01

    Full Text Available Sea-level rise (SLR from global warming may have severe consequences for coastal cities, particularly when combined with predicted increases in the strength of tidal surges. Predicting the regional impact of SLR flooding is strongly dependent on the modelling approach and accuracy of topographic data. Here, the areas under risk of sea water flooding for London boroughs were quantified based on the projected SLR scenarios reported in Intergovernmental Panel on Climate Change (IPCC fifth assessment report (AR5 and UK climatic projections 2009 (UKCP09 using a tidally-adjusted bathtub modelling approach. Medium- to very high-resolution digital elevation models (DEMs are used to evaluate inundation extents as well as uncertainties. Depending on the SLR scenario and DEMs used, it is estimated that 3%–8% of the area of Greater London could be inundated by 2100. The boroughs with the largest areas at risk of flooding are Newham, Southwark, and Greenwich. The differences in inundation areas estimated from a digital terrain model and a digital surface model are much greater than the root mean square error differences observed between the two data types, which may be attributed to processing levels. Flood models from SRTM data underestimate the inundation extent, so their results may not be reliable for constructing flood risk maps. This analysis provides a broad-scale estimate of the potential consequences of SLR and uncertainties in the DEM-based bathtub type flood inundation modelling for London boroughs.

  13. Immunisation status in inner London primary schools.

    OpenAIRE

    Bedford, H E; Masters, J I; Kurtz, Z

    1992-01-01

    In one inner London district health authority, the immunisation status of children attending their routine school entry health interview was reviewed over four terms. During the course of these interviews, school nurses completed a questionnaire with parents that asked for their child's immunisation history and details of family and social background. Parental reporting of immunisation history was compared with district health authority records. Only 56% of children reviewed were found to be ...

  14. Accounting for Impact at Imperial College London

    DEFF Research Database (Denmark)

    Perkmann, Markus; Fini, Riccardo; Ross, Jan-Michael

    We report findings of a study of academic engagement and commercialisation at Imperial College London. We detail the extent of collaboration with industry, consulting, patenting and entrepreneurship by Imperial academics, as well as individuals’ motivations and perceived barriers to engagement. T....... The data stems from archival records held by the College, complemented by external databases, and a survey conducted among all academic staff in 2013....

  15. Forty Years of Crime in London (Journal)

    OpenAIRE

    Shoemaker, R.B.

    2015-01-01

    As a contribution to the fortieth anniversary celebrations of the London Journal, this article provides an overview of the twenty-seven articles which it has published about crime and criminal justice since its inception. While few articles were published in its early years, there has been a big increase in articles published in the last decade, pushing the Journal into the forefront of the historiography on these topics. A survey of the recurring themes in articles about crime, policing, jus...

  16. The role of one large greenspace in mitigating London's nocturnal urban heat island.

    Science.gov (United States)

    Doick, Kieron J; Peace, Andrew; Hutchings, Tony R

    2014-09-15

    The term urban heat island (UHI) describes a phenomenon where cities are on average warmer than the surrounding rural area. Trees and greenspaces are recognised for their strong potential to regulate urban air temperatures and combat the UHI. Empirical data is required in the UK to inform predictions on cooling by urban greenspaces and guide planning to maximise cooling of urban populations. We describe a 5-month study to measure the temperature profile of one of central London's large greenspaces and also in an adjacent street to determine the extent to which the greenspace reduced night-time UHI intensity. Statistical modelling displayed an exponential decay in the extent of cooling with increased distance from the greenspace. The extent of cooling ranged from an estimated 20 m on some nights to 440 m on other nights. The mean temperature reduction over these distances was 1.1 °C in the summer months, with a maximum of 4 °C cooling observed on some nights. Results suggest that calculation of London's UHI using Met Stations close to urban greenspace can underestimate 'urban' heat island intensity due to the cooling effect of the greenspace and values could be in the region of 45% higher. Our results lend support to claims that urban greenspace is an important component of UHI mitigation strategies. Lack of certainty over the variables that govern the extent of the greenspace cooling influence indicates that the multifaceted roles of trees and greenspaces in the UK's urban environment merit further consideration.

  17. UK malaria treatment guidelines.

    Science.gov (United States)

    Lalloo, David G; Shingadia, Delane; Pasvol, Geoffrey; Chiodini, Peter L; Whitty, Christopher J; Beeching, Nicholas J; Hill, David R; Warrell, David A; Bannister, Barbara A

    2007-02-01

    ); quinine is highly effective but poorly tolerated in prolonged dosage and is always supplemented by additional treatment, usually with oral doxycycline. ALL patients treated for P. falciparum malaria should be admitted to hospital for at least 24 h, since patients can deteriorate suddenly, especially early in the course of treatment. Severe falciparum malaria, or infections complicated by a relatively high parasite count (more than 2% of red blood cells parasitized), should be treated with intravenous therapy until the patient is well enough to continue with oral treatment. In the UK, the treatment of choice for severe or complicated malaria is currently an infusion of intravenous quinine. This may exacerbate hypoglycaemia that can occur in malaria; patients treated with intravenous quinine therefore require careful monitoring. Intravenous artesunate reduces high parasite loads more rapidly than quinine and is more effective in treating severe malaria in selected situations. It can also be used in patients with contra-indications to quinine. Intravenous artesunate is unlicensed in the EU. Assistance in obtaining artesunate may be sought from specialist tropical medicine centres, on consultation, for named patients. Patients with severe or complicated malaria should be managed in a high dependency or intensive care environment. They may require haemodynamic support and management of acute respiratory distress syndrome, disseminated intravascular coagulation, renal impairment/failure, seizures, and severe intercurrent infections including gram-negative bacteraemia/septicaemia. Falciparum malaria in pregnancy is more likely to be severe and complicated: the placenta contains high levels of parasites. Stillbirth or early delivery may occur and diagnosis can be difficult if parasites are concentrated in the placenta and scanty in the blood. The treatment of choice for falciparum malaria in pregnancy is quinine; doxycycline is contraindicated in pregnancy but clindamycin can be

  18. Should an iBSc in Management be compulsory for all UK medical students?

    Directory of Open Access Journals (Sweden)

    Singh B

    2015-05-01

    Full Text Available Bharpoor Singh,1 Natalie Ramjeeawon,2 Neil Shah,1 Shawmian Singagireson1 1Imperial College London, London, UK; 2University of Sheffield, Sheffield, UKThe UK medical school system has traditionally offered an intercalated science degree (iBSc to supplement their regular medical degree. However, in recent times with an increasing focus on leadership in the National Health Service (NHS, there has been a shift. More medical schools now offer the option to study an iBSc in Management.I have just spent a year completing an iBSc in Management at Imperial College Business School. Throughout the year I became more and more immersed in our intricate health care system, which is only really apparent to health care professionals whilst on the job. My question to the General Medical Council is – should an iBSc in Management be compulsory for all UK medical students?

  19. Prevalence and correlates of disordered eating in a general population sample: the South East London Community Health (SELCoH) study

    OpenAIRE

    Solmi, F.; Hatch, S. L.; Hotopf, M; Treasure, J.; Micali, N.

    2014-01-01

    Purpose Disordered eating has been shown to be more prevalent than full eating disorders diagnoses. However, research on its prevalence, socio-demographic, psychological correlates, and patterns of service use in multi-ethnic samples is still limited. This paper explores these associations in a South London-based (UK) sample. Methods The South East London Community Health (SELCoH) study is a general population survey (N = 1,698) of individuals aged 16+. Disordered eating was defined as ≥2 pos...

  20. In the loop Large Hadron Collider project - UK engineering firms

    CERN Document Server

    Wilks, N

    2004-01-01

    This paper presents the latest measures being taken to boost the level of UK engineering firms' involvement in research at CERN (Centre for Nuclear Research), including its 27 km circular Large Hadron Collider (LHC) project. Virtually all of the components on this complex project have had to be custom-made, usually in the form of collaboration. It is part of these collaborations that some UK firms have proved they can shine. However, despite the proven capabilities, the financial return continues to be less than the government's funding. Each of the 20 CERN member states provides funds in proportion to its GDP and the UK is the second largest financial contributor. UK firms become price-competitive where a contract calls for a degree of customisation or product development, project management and tight quality control. Development of the Particle Physics Grid, for dissemination and analysis of data from the LHC, continues to provide major supply opportunities for UK manufacturers.

  1. A Brief Analysis on William Blake's London

    Institute of Scientific and Technical Information of China (English)

    张莉; 尚彦飞

    2014-01-01

    William Blake (1757-1827) is a renowned British poet in the 18th century. His lyric poems display the characteristics of romantic spirit, and he is regarded as the forefather of the British Romanticism. His London is a well-known lyric poetry, which is thought to be the best vesicle in the West. This paper will analyse this poem in terms of its form, theme, and im-age and then draw a brief conclusion for the characteristics of William Blake's poem.

  2. On biocoloniality and 'respectability' in contemporary London.

    OpenAIRE

    Narayan, Yasmeen

    2015-01-01

    This essay is framed by discussions on the civil unrest in British cities in 2011, the politics of austerity, the mass unemployment of the young, ‘the war on terror’ and ‘radicalisation’ and the vulnerability of the poor and ‘unrespectable’. It advances a concept of biocoloniality and explores ‘respectability’, class and transnational postcolonial urban cultures in contemporary London. The essay argues for a theorisation which can account for how a divided subject produces the effect of an un...

  3. "More Swimming Lessons from the London Whale"

    OpenAIRE

    Jan KREGEL

    2013-01-01

    This policy brief by Senior Scholar and Program Director Jan Kregel builds on an earlier analysis (Policy Note 2012/6) of JPMorgan Chase and the actions of the "London Whale", and what this episode reveals about the larger risks inherent in the financial system. It is clear that the Dodd-Frank Act failed to prevent massive losses by one of the world's largest banks. This is undeniable evidence that work remains to be done to reform the financial system. Toward this end, Kregel reviews the fin...

  4. Parallel to the Situational Judgement Test: is the Educational Performance Measure fair in ranking medical students on the UK Foundation Programme?

    Directory of Open Access Journals (Sweden)

    Singh Sidhu H

    2016-10-01

    Full Text Available Harmeet Singh Sidhu,1 Adil Mahmood,2 Ranjodh Sanghera,1 Jay Mandan11Faculty of Medicine, Imperial College London, London, UK; 2Faculty of Life Sciences and Medicine, King’s College London, London, UKWe readily appraised the expert opinion by Singagireson et al which explored the fairness of using the Situational Judgement Test (SJT to rank medical students as part of the UK Foundation Programme.1 Although we agree with many of the points raised, we feel it is equally important to discuss the role of the Educational Performance Measure (EPM, which has comparable weighting to the SJT in ranking medical students. Therefore, we aim to explore whether the EPM is a fair measure in determining the allocation of foundation-training jobs to newly qualified doctors.View the original paper by Singagireson et al

  5. The Volunteering Legacy of London 2012 Games. A Pilot Study.

    OpenAIRE

    2016-01-01

    The hosting of the London 2012 Olympic Games was seen as an opportunity to harness the enthusiasm of the 70000 volunteers involved and to provide a volunteer legacy post event. A total of 77 London 2012 volunteers completed a web-based open-ended survey. The participants were asked to indicate their level of current volunteering engagement and whether volunteering at the Games had an impact on their current volunteering levels. The study found that the London Olympics were the first volunteer...

  6. An audit of HIV treatment outcomes in a UK inner city cohort.

    Science.gov (United States)

    Bird, E; Cormack, I; Rodgers, M; Phillips, D; Elgalib, A

    2016-10-01

    We describe the demographics and treatment outcomes of a HIV-infected cohort from Croydon University Hospital, London, UK. We showed that the Croydon Cohort had good viral load suppression (98.6% with viral load < 100 copies/ml and 99.0% with viral load < 200 copies/ml) despite being a potentially challenging cohort in a deprived area of London. The viral load outcomes are better than the Public Health England data from 2014 and the latest British HIV Association audit using data from 2009.

  7. Five Rings: Enclosing the London 2012 Olympic Games

    Directory of Open Access Journals (Sweden)

    Jonathan William Gardner

    2013-08-01

    Full Text Available Considering the successive iterations of the fence surrounding the London 2012 Olympic site in Stratford, east London, I demonstrate that during the five periods of enclosure considered, these boundaries have highlighted the London Games’ contested past, present, and future. An examination of the material and discursive constructions of each of these boundaries shows the Janus-faced nature of their relationship to the wider ‘mega-event’. I conclude that though the purpose of such enclosures may initially seem obvious, in actuality they, as parts of a wider assemblage, can act unpredictably both to support and challenge the Olympic brand and its existence in this part of east London.

  8. James Henry Greathead and the London Underground

    Directory of Open Access Journals (Sweden)

    Laurence Wright

    2017-01-01

    Full Text Available This article investigates the origins and early history of the device known as the ‘Greathead Shield’, an important innovation in Victorian engineering crucial to constructing the London Underground. The aim is to explore the basis on which, many years later, a South African engineer, James Henry Greathead, was accorded prominent public acknowledgment, in the form of a statue, for ‘inventing’ the Shield. From a cultural studies perspective, how is the meaning of ‘invention’ to be understood, given that several other brilliant engineers were involved? The question is adjudicated using the notion of cultural ‘extelligence’, seen in relation to several contemporary and historical accounts, including Greathead’s own record of his achievements in the proceedings of the Institution of Civil Engineers and presented in The City and South London Railway (1896, edited by James Forrest. The paper was first delivered at the conference on ‘Novelty and Innovation in the Nineteenth Century’ held at the North-West University in May 2016.

  9. Stabbing and safeguarding in children and young people: a Pan-London service evaluation and audit.

    Science.gov (United States)

    Apps, John R; Williams, Carrie; McGuinness, Anne; Gabbie, Susie; Sutcliffe, Alastair G

    2013-07-01

    To characterize paediatric presentations of stabbing to emergency departments across London and to audit existing referral rates to the police and social services against the new standard set by the General Medical Council. Retrospective multi-centre service evaluation/audit. All emergency departments within London. Patients under 18 years of age presenting to emergency departments with non-accidental stabbing between 1 April 2007 and 30 April 2009. Patient age, nature of assault, assailant, injuries and management. Rates of documented referral to police and social services, as mandated by GMC guidance. A total of 381 presentations were identified from 20 out of the 32 hospitals in London, 160 of whom were less than 16 years old. The majority were seen only by emergency department staff and only a minority (28%) were admitted. Three died in the departments. A knife was the commonest weapon and the limbs the most common site of injury. Referrals to police were documented in only 30% of patients (43% if <16 years old) and to social services in 16% (31% if <16 years old) of those discharged. In the majority, there was no documentation (police 64%, social services 79%). A significant number of paediatric stabbings present to emergency departments across London. The majority of these are discharged directly from departments. Of those discharged, documentation regarding referral rates to Police and Social Services was poor, and documented referral rates low. This study covered a period prior to the introduction of new General Medical Council guidance and a repeat audit to assess subsequent documented referrals is required.

  10. CMS Centre at CERN

    CERN Multimedia

    2007-01-01

    A new "CMS Centre" is being established on the CERN Meyrin site by the CMS collaboration. It will be a focal point for communications, where physicists will work together on data quality monitoring, detector calibration, offline analysis of physics events, and CMS computing operations. Construction of the CMS Centre begins in the historic Proton Synchrotron (PS) control room. The historic Proton Synchrotron (PS) control room, Opened by Niels Bohr in 1960, will be reused by CMS to built its control centre. TThe LHC@FNAL Centre, in operation at Fermilab in the US, will work very closely with the CMS Centre, as well as the CERN Control Centre. (Photo Fermilab)The historic Proton Synchrotron (PS) control room is about to start a new life. Opened by Niels Bohr in 1960, the room will be reused by CMS to built its control centre. When finished, it will resemble the CERN Contro...

  11. UK academics share their thoughts on Hinkley Point C

    Energy Technology Data Exchange (ETDEWEB)

    Dalton, David [NucNet, Brussels (Belgium)

    2016-10-15

    The proposed Hinkley Point C nuclear power plant project has experienced controversy in the public since its inception. However the proposed Hinkley plant has many benefits. It will be the biggest construction site in Europe, providing 25,000 jobs. It will generate low carbon energy, providing enough power for six million homes, and supplying seven per cent of the UK's electricity needs over its 60 year lifetime. Six experts from Imperial College London, one of Europe's top science-based universities, give their opinions on Hinkley Point C.

  12. Remarks at Thomson Reuters Newsmaker Event, London, U.K., June 19, 2013

    OpenAIRE

    Kim, Jim Yong

    2013-01-01

    Jim Yong Kim, President of the World Bank Group, discusses climate change as being a fundamental threat to economic development and the fight against poverty. He releases the new climate change report “Climate Extremes: Regional Impacts and the Case for Resilience” which talks about the challenges we’d be facing if the global temperature rose by two degrees Celsius. He talks about developing tools that help countries better assess and adapt to climate change, including greenhouse gas emiss...

  13. Marketing lifestyle drugs==>to consumers = increased market share. 7-8 September 1999, London, UK.

    Science.gov (United States)

    Gianfrate, F

    1999-11-01

    This conference focused on 'lifestyle' drugs, the kind of medicines treating conditions not considered as diseases, such as erectile dysfunction, male baldness, stress, etc, to improve quality of life and well-being. The lifestyle area is the fastest growing area in pharmaceuticals, driven by drugs such as Viagra (sildenafil; Pfizer Inc), Propecia (finasteride; Merck & Co Inc), Xenical (orlistat; F Hoffmann-La Roche Ltd) and others. The aging population in developed countries has a new perception of health, which is an improvement of wellness. Patients are more informed and conscious about their own health and the higher involvement in copayment and decision-making are changing pharmaceutical markets and, consequently, pharmaceutical industry's business and R&D strategies. Successful marketing of lifestyle drugs requires taking into account the above scenario, using new communication tools and being able to re-think the conventional marketing strategies adopted so far.

  14. Highlights from Faraday Discussion 184: Single-Molecule Microscopy and Spectroscopy, London, UK, September 2015.

    Science.gov (United States)

    Gellings, E; Faez, S; Piatkowski, L

    2016-02-07

    The 2015 Faraday Discussion on single-molecule microscopy and spectroscopy brought together leading scientists involved in various topics of single-molecule research. It attracted almost a hundred delegates from a broad spectrum of backgrounds and experience levels - from experimentalists to theoreticians, from biologists to materials scientists, from masters students to Nobel Prize Laureates. The meeting was merely a reflection of how big of an impact the ability to detect individual molecules has had on science over the past quarter of a century. In the following we give an overview of the topics covered during this meeting and briefly highlight the content of each presentation.

  15. Detection of Factor XIII deficiency: data from multicentre exercises amongst UK NEQAS and PRO-RBDD project laboratories.

    Science.gov (United States)

    Jennings, I; Kitchen, S; Menegatti, M; Palla, R; Walker, I; Makris, M; Peyvandi, F

    2017-08-01

    FXIII deficiency is a rare bleeding disorders, and specific FXIII assays are recommended to detect this deficiency. We investigated the performance and accuracy of FXIII investigations in two exercises, comparing centres enrolled in the PRO-RBDD project (prospective data collection on patients with fibrinogen and Factor XIII deficiencies), and UK NEQAS BC centres. Samples from a FXIII deficient subject and a normal donor were sent to participating centres, to investigate for FXIII deficiency, and interpret their results. Median, coefficient of variation and range were determined. Results were returned from 98 UK NEQAS BC and 28 PRO-RBDD centres. Up to 40% of UK NEQAS BC and 52% of PRO-RBDD centres reported clot solubility results - with diagnostic errors by two NEQAS BC centres (false negatives for the FXIII deficient sample) and one PRO-RBDD centre (false positive for the normal sample). Over 70% of UK NEQAS BC centres and PRO-RBDD centres performed FXIII assays. Median results were similar between the two groups, with the exception of sample 3 in survey 2 (5.5 vs. 14.0 μ/dl for UK NEQAS BC and PRO-RBDD centres respectively, P UK NEQAS BC centres. Approximately 70% of centres now employ FXIII assays, complying with international recommendations. However, solubility tests continue to be used. Our data show this can be successful, depending on the sensitivity of the method in use. Diagnostic errors are made by centres using both solubility screens and FXIII assays, and laboratories should ensure good quality assurance procedures to improve diagnostic accuracy. © 2017 John Wiley & Sons Ltd.

  16. UK victims of trafficking

    Directory of Open Access Journals (Sweden)

    Bob Burgoyne

    2006-05-01

    Full Text Available Analysis of court cases shows how hard it is forvictims of trafficking to win the right to remain in the UK. Case law is inconsistent and more research and data collection are urgently needed.

  17. Alcohol gel ingestion amongst homeless Eastern and Central Europeans in\\ud London: assessing the effects on cognitive functioning and psychological health

    OpenAIRE

    Soar, Kirstie; Papaioannou, G.; Dawkins, Lynne

    2016-01-01

    Background: Intentional consumption of alcohol based hand gels has been reported\\ud especially amongst non-UK national, alcohol dependent, homeless individuals in\\ud London. Whilst alcohol misuse is known to be associated with impaired cognitive\\ud functioning and mental health problems, the effects of additional ingestion of alcohol gel\\ud are unknown. Objectives: To explore cognitive and psychological functioning in users\\ud who intentionally ingest alcohol gel compared with ethyl-alcohol o...

  18. Changing the Subject: English in London, 1945-1967

    Science.gov (United States)

    Yandell, John

    2014-01-01

    Two recent books, "English Teachers in a Postwar Democracy: Emerging Choice in London Schools, 1945-1965" and "The London Association for the Teaching of English, 1947-67: A History," explore an important period in the development of English as a school subject and in the remaking of the professional identity of English…

  19. Alternative Spaces of Learning in East London: Opportunities and Challenges

    Science.gov (United States)

    Sneddon, Raymonde; Martin, Peter

    2012-01-01

    This article emerges from an ongoing exploration into how British minority ethnic communities in the London area create spaces in community-based programs to maintain or develop their languages and literacies. In London, more than one-third of the 850,000 school children speak a language other than English at home (Baker & Eversley, 2000).…

  20. Changing the Subject: English in London, 1945-1967

    Science.gov (United States)

    Yandell, John

    2014-01-01

    Two recent books, "English Teachers in a Postwar Democracy: Emerging Choice in London Schools, 1945-1965" and "The London Association for the Teaching of English, 1947-67: A History," explore an important period in the development of English as a school subject and in the remaking of the professional identity of English…

  1. Spatial and temporal associations of road traffic noise and air pollution in London: Implications for epidemiological studies.

    Science.gov (United States)

    Fecht, Daniela; Hansell, Anna L; Morley, David; Dajnak, David; Vienneau, Danielle; Beevers, Sean; Toledano, Mireille B; Kelly, Frank J; Anderson, H Ross; Gulliver, John

    2016-03-01

    Road traffic gives rise to noise and air pollution exposures, both of which are associated with adverse health effects especially for cardiovascular disease, but mechanisms may differ. Understanding the variability in correlations between these pollutants is essential to understand better their separate and joint effects on human health. We explored associations between modelled noise and air pollutants using different spatial units and area characteristics in London in 2003-2010. We modelled annual average exposures to road traffic noise (LAeq,24h, Lden, LAeq,16h, Lnight) for ~190,000 postcode centroids in London using the UK Calculation of Road Traffic Noise (CRTN) method. We used a dispersion model (KCLurban) to model nitrogen dioxide, nitrogen oxide, ozone, total and the traffic-only component of particulate matter ≤2.5μm and ≤10μm. We analysed noise and air pollution correlations at the postcode level (~50 people), postcodes stratified by London Boroughs (~240,000 people), neighbourhoods (Lower layer Super Output Areas) (~1600 people), 1km grid squares, air pollution tertiles, 50m, 100m and 200m in distance from major roads and by deprivation tertiles. Across all London postcodes, we observed overall moderate correlations between modelled noise and air pollution that were stable over time (Spearman's rho range: |0.34-0.55|). Correlations, however, varied considerably depending on the spatial unit: largest ranges were seen in neighbourhoods and 1km grid squares (both Spearman's rho range: |0.01-0.87|) and was less for Boroughs (Spearman's rho range: |0.21-0.78|). There was little difference in correlations between exposure tertiles, distance from road or deprivation tertiles. Associations between noise and air pollution at the relevant geographical unit of analysis need to be carefully considered in any epidemiological analysis, in particular in complex urban areas. Low correlations near roads, however, suggest that independent effects of road noise and

  2. Slowly Evolving Trends in Temporal Lobe Epilepsy Management at London Health Sciences Centre

    Science.gov (United States)

    Blume, Warren T.

    2013-01-01

    Although the advent of MRI impacted significantly our presurgical investigation, ictal semiology with interictal and ictal EEG has clearly retained its roles in localizing epileptogenesis. MRI-identified lesions considered epileptogenic on semiological and electroencephalographic grounds have increased the likelihood of resective surgery effectiveness whereas a nonlesional MRI would diminish this probability. Ictal propagation and the interplay between its source and destination have emerged as a significant component of seizure evaluation over the past 30 years. PMID:23533736

  3. Leading increasingly linguistically diverse London schools

    Directory of Open Access Journals (Sweden)

    Dina Mehmedbegović

    2008-10-01

    Full Text Available Engaging with bilingual parents, students and teachers with little awareness of the benefits of bilingualism has initiated a search for factors resulting in the low value attached to certain types of bilingualism. Working on the hypothesis that prevalent practice is influenced more by attitudes to bilingualism rather than relevant research and pedagogical theory, this research focuses on attitudes. This small-scale qualitative study conducted with a group of London headteachers provides an insight into the attitudes to bilingualism and how they impact on policy and practice in schools with significant proportions of multilingual learners. It also raises the question if schools which claim to support multilingual students in realising their full potential can achieve that without including home languages as an integral part of learning.

  4. Turner's prize[London transport policy

    Energy Technology Data Exchange (ETDEWEB)

    Sherrington, M.

    2000-10-26

    The article describes Ken Livingstone's plans for solving London's traffic problems: Derek Turner will be 'in charge of the capital's streets' but Livingstone will chair the board meetings. The radical new scheme will apply to both the Greater London Authority, its transport branch Transport for London (TfL) and 33 London Boroughs. Within TfL there is a core division called 'street management services' which has five area teams for day-to-day street management including road maintenance and street lighting. Other departments are communications, support services, traffic technology services, service development and performance, a London bus department and a department concentrating on congestion charging. There are plans to support pedestrians and cyclists but 'bus travel is really what it is all about'.

  5. Resuscitation of general paediatrics in the UK.

    Science.gov (United States)

    Wacogne, I; Scott-Jupp, R; Chambers, T

    2006-12-01

    "The report of my death was an exaggeration", said Mark Twain. For a dying specialty, general paediatrics has certainly been looking very healthy recently. It is timely to examine why our specialty was thought to be at such risk, and to explore why, although in many cases shocked and confused, it is well on the way to recovery. This article explores what is needed to keep it healthy to ensure that the general paediatrician is at the centre of the delivery of paediatrics in the UK.

  6. UK population norms for EQ-5D

    OpenAIRE

    Paul Kind; Geoffrey Hardman; Susan Macran

    1999-01-01

    This discussion paper presents data from the Department of Health funded Measurement and Valuation of Health survey conducted at the Centre for Health Economics in 1993. This was a nationally representative interview survey of 3395 men and women aged 18 or over living in the UK. Amongst other things, the survey collected information on health status using the EuroQol (EQ-5D) descriptive system. The data is presented as a series of tables of age/sex population norms for the EQ-5D, for both sel...

  7. Cochlear implantation in children with complex needs: The perceptions of professionals at cochlear implant centres

    NARCIS (Netherlands)

    Archbold, S.M.; Athalye, S.; Mulla, I.; Harrigan, S.; Wolters, N.; Isarin, J.; Knoors, H.E.T.

    2016-01-01

    Objective To explore the views of cochlear implant centre teams about the process of referral, assessment and rehabilitation for children with complex needs. Methods An on-line survey of cochlear implant centres in the UK and in the Netherlands was carried out, with both quantitative and qualitative

  8. Congressional Science Fellow tackles science policy for U.K.

    Science.gov (United States)

    Moses, Julie J.

    After an AGU Congressional Science Fellowship in 1997-1998,I decided to pursue science policy further. I spied an ad in the Sunday Washington Post advertising for someone with a science degree, who also had knowledge of the United Kingdom, and science policy experience on Capitol Hill. In addition to my Ph.D. from the University of California at Los Angeles and the Congressional Science Fellowship, I had spent two years in the U.K. as a post-doc at Queen Mary and Westfield College in London.I applied for the job, which was at the British Embassy in Washington, D.C., and was hired. The UK Foreign Office has a tradition of hiring many of its embassy staff locally; they consider knowledge of local politics and issues very use ful for their interests. Now I cover hard science issues, including space and the Internet for Her Majesty's Government.

  9. How appropriate are the English language test requirements for non-UK-trained nurses? A qualitative study of spoken communication in UK hospitals.

    Science.gov (United States)

    Sedgwick, Carole; Garner, Mark

    2017-06-01

    Non-native speakers of English who hold nursing qualifications from outside the UK are required to provide evidence of English language competence by achieving a minimum overall score of Band 7 on the International English Language Testing System (IELTS) academic test. To describe the English language required to deal with the daily demands of nursing in the UK. To compare these abilities with the stipulated levels on the language test. A tracking study was conducted with 4 nurses, and focus groups with 11 further nurses. The transcripts of the interviews and focus groups were analysed thematically for recurrent themes. These findings were then compared with the requirements of the IELTS spoken test. The study was conducted outside the participants' working shifts in busy London hospitals. The participants in the tracking study were selected opportunistically;all were trained in non-English speaking countries. Snowball sampling was used for the focus groups, of whom 4 were non-native and 7 native speakers of English. In the tracking study, each of the 4 nurses was interviewed on four occasions, outside the workplace, and as close to the end of a shift as possible. They were asked to recount their spoken interactions during the course of their shift. The participants in the focus groups were asked to describe their typical interactions with patients, family members, doctors, and nursing colleagues. They were prompted to recall specific instances of frequently-occurring communication problems. All interactions were audio-recorded, with the participants' permission,and transcribed. Nurses are at the centre of communication for patient care. They have to use appropriate registers to communicate with a range of health professionals, patients and their families. They must elicit information, calm and reassure, instruct, check procedures, ask for and give opinions,agree and disagree. Politeness strategies are needed to avoid threats to face. They participate in medical

  10. Birthweight by gestational age and its effect on perinatal mortality in white and in Punjabi births: experience at a district general hospital in West London 1967-1975.

    Science.gov (United States)

    Dawson, I; Golder, R Y; Jonas, E G

    1982-11-01

    At Hillingdon Hospital in West London two main ethnic groups: 'UK' (i.e. white European) and 'Indian' (i.e. Punjabi) account for the bulk of obstetric work load. Birthweight by gestational age graphs were calculated for some 6000 Indian and 18000 UK infants born between 1967 and 1975 inclusive. A mean weight difference at term favoured UK male babies by 240 g and UK female babies by 230 g. Though the crude perinatal results in the two populations were not significantly different, the perinatal mortality of infants less than 2500 g in birthweight was lower in the Indian than the UK population, particularly in the 1500-2400 g group. This is attributed to a levelling off in intrauterine growth from 36 to 37 weeks gestation onwards in Indian compared with UK pregnancies, so that they were more mature than UK births of the same weight. However light-for-dates births, defined as birthweights below the 10th centile of weight-for-gestational age on their own ethnic and sex specific standards pose problems, irrespective of ethnic background.

  11. Client Centred Desing

    DEFF Research Database (Denmark)

    Ørngreen, Rikke; Nielsen, Janni; Levinsen, Karin

    2008-01-01

    In this paper we argue for the use of Client Centred preparation phases when designing complex systems. Through Client Centred Design human computer interaction can extend the focus on end-users to alse encompass the client's needs, context and resources....

  12. Mentoring perception and academic performance: an Academic Health Science Centre survey.

    Science.gov (United States)

    Athanasiou, Thanos; Patel, Vanash; Garas, George; Ashrafian, Hutan; Shetty, Kunal; Sevdalis, Nick; Panzarasa, Pietro; Darzi, Ara; Paroutis, Sotirios

    2016-10-01

    To determine the association between professors' self-perception of mentoring skills and their academic performance. Two hundred and fifteen professors from Imperial College London, the first Academic Health Science Centre (AHSC) in the UK, were surveyed. The instrument adopted was the Mentorship Skills Self-Assessment Survey. Statement scores were aggregated to provide a score for each shared core, mentor-specific and mentee-specific skill. Univariate and multivariate regression analyses were used to evaluate their relationship with quantitative measures of academic performance (publications, citations and h-index). There were 104 professors that responded (response rate 48%). There were no statistically significant negative correlations between any mentoring statement and any performance measure. In contrast, several mentoring survey items were positively correlated with academic performance. The total survey score for frequency of application of mentoring skills had a statistically significant positive association with number of publications (B=0.012, SE=0.004, p=0.006), as did the frequency of acquiring mentors with number of citations (B=1.572, SE=0.702, p=0.030). Building trust and managing risks had a statistically significant positive association with h-index (B=0.941, SE=0.460, p=0.047 and B=0.613, SE=0.287, p=0.038, respectively). This study supports the view that mentoring is associated with high academic performance. Importantly, it suggests that frequent use of mentoring skills and quality of mentoring have positive effects on academic performance. Formal mentoring programmes should be considered a fundamental part of all AHSCs' configuration. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  13. Air quality and public health impacts of UK airports. Part II: Impacts and policy assessment

    Science.gov (United States)

    Yim, Steve H. L.; Stettler, Marc E. J.; Barrett, Steven R. H.

    2013-03-01

    The potential adverse human health impacts of emissions from UK airports have become a significant issue of public concern. We produce an inventory of UK airport emissions - including emissions from aircraft landing and takeoff operations, aircraft auxiliary power units (APUs) and ground support equipment (GSE) - with quantified uncertainty. Emissions due to more than 95% of UK passenger enplanements are accounted for. We apply a multi-scale air quality modelling approach to assess the air quality impacts of UK airports. Using a concentration-response function we estimate that 110 (90% CI: 72-160) early deaths occur in the UK each year (based on 2005 data) due to UK airport emissions. We estimate that up to 65% of the health impacts of UK airports could be mitigated by desulphurising jet fuel, electrifying GSE, avoiding use of APUs and use of single engine taxiing. Two plans for the expansion of UK airport capacity are examined - expansion of London Heathrow and new hub airport in the Thames Estuary. Even if capacity is constrained, we find that the health impacts of UK airports still increases by 170% in 2030 due to an increasing and aging population, increasing emissions, and a changing atmosphere. We estimate that if Heathrow were to be expanded as per previous UK Government plans, UK-wide health impacts in 2030 would increase by 4% relative to the 2030 constrained case, but this increase could become a 48% reduction if emissions mitigation measures were employed. We calculate that 24% of UK-wide aviation-attributable early deaths could be avoided in 2030 if Heathrow were replaced by a new airport in Thames Estuary because the location is downwind of London, where this reduction occurs notwithstanding the increase in aircraft emissions. A Thames hub airport would (isolated from knock-on effects at other airports) cause 60-70% fewer early deaths than an expanded Heathrow, or 55-63% fewer early deaths than an unexpanded Heathrow. Finally, replacing Heathrow by a

  14. Non-European nurses' perceived barriers to UK nurse registration.

    Science.gov (United States)

    Allan, Helen; Westwood, Sue

    2016-05-11

    Aim To conduct a scoping project to identify perceived barriers to UK nurse registration as experienced by internationally educated nurses working as healthcare assistants in the UK. Method Eleven internationally educated nurses working as healthcare assistants in two London hospitals attended two facilitated focus groups. Qualitative thematic analysis was used to analyse the data. Findings Study participants articulated frustration with UK English language testing requirements and a sense of injustice and unfairness relating to: double standards for nurses educated within and outside of the European Union (EU) and European Economic Area (EEA); and what was perceived, by some, as arbitrary English language testing with unnecessarily high standards. Differences among study participants related to issues of competency and accountability regarding English language skills and passing English language skills tests, with many feeling they were playing 'a game' where the rules kept changing. Conclusion Language testing barriers are impeding UK nurse registration for some internationally educated nurses from outside the EU and EEA who, as a result, are working as healthcare assistants. The provision of English language training by employers would improve their prospects of achieving nurse registration.

  15. UK Frac Sand Resources

    OpenAIRE

    Mitchell, C J

    2015-01-01

    Although still just a glimmer in the gas man’s eye, the prospect of shale hydrocarbon (oil and gas) development in the UK has many companies thinking about the industrial minerals it will require. Chief amongst these is silica sand which is used as a ‘proppant’ in the hydraulic fracturing, or ‘fracking’, of shales to help release the gas. The UK has large resources of sand and sandstone, of which only a small proportion have the necessary technical properties that classify them as ‘silica san...

  16. Teaching the History of Astronomy On Site in London

    Science.gov (United States)

    French, Linda M.

    2016-01-01

    In the autumn of 2014, the author had the opportunity to teach a class on the history of astronomy in England as part of a study abroad experience for students at Illinois Wesleyan University. The philosophy of the program is to use the rich cultural environment of London as a setting for active learning. In the classroom, students read and discussed selected works by Ptolemy, Copernicus, Kepler, Galileo, and Herschel. We visited Stonehenge, the Royal Greenwich Observatory, the London Science Museum, the London Monument, and the library of the Royal Astronomical Society. Lessons learned from the experience will be shared.

  17. VICTOR: Vinflunine in advanced metastatic transitional cell carcinoma of the urothelium: A retrospective analysis of the use of vinflunine in multi-centre real life setting as second line chemotherapy through Free of Charge Programme for patients in the UK and Ireland.

    Science.gov (United States)

    Hussain, Syed A; Ansari, Jawaher; Huddart, Robert; Power, Derek G; Lyons, Jeanette; Wylie, James; Vilarino-Varlela, Maria; Elander, Nils O; McMenemin, Rhona; Pickering, Lisa M; Faust, Guy; Chauhan, Seema; Jackson, Richard J

    2017-03-01

    There is no standard of care in the UK or Ireland for second-line chemotherapy for patients with advanced transitional cell carcinoma (TCCU). Vinflunine is approved for TCCU patients who have failed a platinum-based regimen, and is standard of care in Europe but is not routinely available in the UK. Data were collected retrospectively on patients who received vinfluine as a second-line treatment. The aims were to document the toxicity and efficacy in a real life setting. Data were collected on 49 patients from 9 sites across the UK and Ireland [median age, 64 (IQR, 57-70) years, 33 males]. All patients had advanced metastatic TCCU. Thirteen patients had bone or liver metastases, 4 patients had PS 2 and 11 patients had HB life data from Europe. Toxicity is further reduced with prophylactic laxative and oral antibiotics. Vinflunine is an efficient and tolerable second line treatment in advanced TCCU.

  18. 3-D GIS : Virtual London and beyond

    Directory of Open Access Journals (Sweden)

    Michael Batty

    2006-10-01

    Full Text Available In this paper, we outline how we have developed a series of technologies to enable detailed interactive 3-D Geographical Information Systems (GIS based models of cities to be created. Until relatively recently these models have been developed in Computer Aided Design (CAD software more often then in GIS. One of the main reasons was that ‘3-D GIS’ was often only 2.5-D under closer inspection. This is changing, and by straddling both technologies, and integrating others, we show how these models in turn enable planning information, statistics, pollution levels, sea level rises and much more to be visualised and analysed in the context of the 3-D city model. The client for ‘Virtual London’ is the Greater London Authority (GLA and their aim is to develop improved dissemination of planning information, which is explored. We then argue that virtual cities should go well beyond the traditional conceptions of 3-D GIS and CAD into virtual worlds and online design. But we also urge caution in pushing the digital message too far, showing how more conventional tangible media is always necessary in rooting such models in more realistic and familiar representations.

  19. Tracker electronics testing at Imperial College London

    CERN Document Server

    PPARC, UK

    2006-01-01

    Jonathon Fulcher and Rob Bainbridge testing a rack of CMS Tracker readout electronics at Imperial College London. The signals from the front end APV chips will be transmitted optically to racks of electronics ~100m away in an adjacent underground cavern where they are fed into ~20 crates where 500 CMS Front End Driver boards (FEDs) are located. The FED inputs are 8 fibre ribbons, each ribbon consisting of 12 fibres, each fibre carrying the serially multiplexed data originating from 2 APVs. To test the FEDs special tester boards have been designed to produce simulated APV data in optical form. In the picture the yellow cables are the fibres, which originate from the FED tester boards on the left hand side of the crate as 96 individual fibres, which are then combined into the 8 fibre ribbons feeding the FED board on the right hand side of the crate. Fig. 2 shows an APV25 test board mounted in the X-ray irradiation setup, Fig. 3 the X-ray machine where the chips are irradiated and Fig. 4 the MGPA (Multi-Gain Pre...

  20. Collider – the LHC in London

    CERN Multimedia

    Emma Sanders

    2013-01-01

    In November the London Science Museum will open a major new exhibition about the LHC. The project marks an ambitious new approach for the museum who will work with an eclectic design team that includes a video artist and a playwright. Both Olivier Award winners, they are more renowned for their work on stage and screen than inside museums.   Image courtesy of Science Museum / Nissen Richards Studio. The Science Museum team came to Geneva expecting to be blown away by the extraordinary physics and engineering at CERN and they weren’t disappointed. But what impressed them most was the people who made it all happen. Physicists of all kinds, restaurant staff, engineers, administrators, those working in transport and logistics, all had in common a passion for CERN and an enthusiasm for communicating their work. “What really struck us was how every single person mentioned the spirit of international collaboration and the importance of curiosity,” Alison Boyle told the ...

  1. Volatile organic compound fluxes and concentrations in London (ClearfLo)

    Science.gov (United States)

    Valach, Amy; Langford, Ben; Nemitz, Eiko; MacKenzie, Rob; Hewitt, Nick

    2014-05-01

    Volatile organic compounds (VOCs) from anthropogenic sources such as fuel combustion or evaporative emissions can directly and indirectly affect human health. Some VOCs, such as benzene and 1,3- butadiene are carcinogens. These and other VOCs contribute to the formation of ozone (O3) and aerosol particles, which have effects on human health and the radiative balance of the atmosphere. Although in the UK VOC emissions are subject to control under European Commission Directive 2008/50/EC and emission reducing technologies have been implemented, urban air pollution remains a concern. Urban air quality is likely to remain a priority since currently >50% of the global population live in urban areas with trends in urbanization and population migration predicted to increase. The ClearfLo project is a large multi-institutional consortium funded by the UK Natural Environment Research Council (NERC) and provides integrated measurements of meteorology, gas phase and particulate composition of the atmosphere over London. Both long term and IOP measurements were made at street and elevated locations at a range of sites across London and its surroundings during 2011 and 2012. Mixing ratios of a selection of nine VOCs were measured using a high sensitivity proton transfer reaction-mass spectrometer (PTR-MS) at a ground level urban background (North Kensington) and kerbside (Marylebone Road) site during the winter IOP. VOC fluxes were measured by virtually disjunct eddy covariance (vDEC) at an elevated urban site (King's College Strand) in Aug-Dec 2012. Our results for the first IOP showed that most of the selected compound concentrations depended on traffic emissions, although there was a marked difference between the urban background and kerbside sites. We identified some temperature effects on VOC concentrations. We also present the first analyses of VOC flux measurements over London. Preliminary analyses indicate most compounds associated with vehicle emissions closely

  2. Female condom launched in UK.

    Science.gov (United States)

    1992-01-01

    The lone-awaited female condom, Femidom, is to be launched at the end of September by manufacturers Chartex. It is being welcomed by the FPA [Family Planning Association] and other family planning experts as a valuable addition to the existing range of contraceptive methods and as an alternative to the male condom in offering effective protection against sexually transmitted diseases including HIV. A lubricated, loose-fitting polyurethane sheath, Femidom is inserted into the vagina at any time before sex. An inner ring holds the condom in place beyond the pubic bone and an outer ring lies flat against the vulva. In addition to extending choice, it is under direct control of the woman. As FPA Director Doreen Massey puts it: "We have to face the fact that some women who want safer sex can't get their partners to use condoms. for the 1st time with Femidom, you can insist that if he won't use a condom, you'll use yours." In trails of self-selected couples, up to 2/3 of women and their partners found the product acceptable. a study at the Institute of Population Studies in Exeter showed that while some couples had initial misgivings about the condom's size and appearance, especially its visibility when in position, these often declined with repeated use. Researcher Dr. Nicholas Ford pointed out that if the female condom makes a woman feel unattractive, her partner's comments may well influence these feelings. Users' experience of insertion and the condom's comfort also improved with repeated use. While there are no large studies showing ranges of effectiveness, it is likely to be as effective as the male condom (about 85%-98%). In a study of 106 women at the margaret Pyke Center in London, there were 7 unplanned pregnancies: 4 were due to inconsistent use of the method and 3 were method failures. Breakages were rare. 1/3 of participants dropped out in the 1st month. Users should continue with their existing contraceptive method until they are sure that they are using

  3. A tale of two cities: Comparison of impacts on CO2 emissions, the indoor environment and health of home energy efficiency strategies in London and Milton Keynes

    Science.gov (United States)

    Shrubsole, C.; Das, P.; Milner, J.; Hamilton, I. G.; Spadaro, J. V.; Oikonomou, E.; Davies, M.; Wilkinson, P.

    2015-11-01

    Dwellings are a substantial source of global CO2 emissions. The energy used in homes for heating, cooking and running electrical appliances is responsible for a quarter of current total UK emissions and is a key target of government policies for greenhouse gas abatement. Policymakers need to understand the potential impact that such decarbonization policies have on the indoor environment and health for a full assessment of costs and benefits. We investigated these impacts in two contrasting settings of the UK: London, a predominantly older city and Milton Keynes, a growing new town. We employed SCRIBE, a building physics-based health impact model of the UK housing stock linked to the English Housing Survey, to examine changes, 2010-2050, in end-use energy demand, CO2 emissions, winter indoor temperatures, airborne pollutant concentrations and associated health impacts. For each location we modelled the existing (2010) housing stock and three future scenarios with different levels of energy efficiency interventions combined with either a business-as-usual, or accelerated decarbonization of the electricity grid approach. The potential for CO2 savings was appreciably greater in London than Milton Keynes except when substantial decarbonization of the electricity grid was assumed, largely because of the lower level of current energy efficiency in London and differences in the type and form of the housing stock. The average net impact on health per thousand population was greater in magnitude under all scenarios in London compared to Milton Keynes and more beneficial when it was assumed that purpose-provided ventilation (PPV) would be part of energy efficiency interventions, but more detrimental when interventions were assumed not to include PPV. These findings illustrate the importance of considering ventilation measures for health protection and the potential variation in the impact of home energy efficiency strategies, suggesting the need for tailored policy

  4. BSE in the UK

    DEFF Research Database (Denmark)

    Jensen, Karsten Klint

    2004-01-01

    The 2000 BSE Inquiry report points out that the most serious failure of the UK Government was one of risk communication. This paper argues that the government's failure to communicate the risks BSE posed to humans to a large degree can be traced back to a lack of transparency in the first risk...

  5. Malnutrition in the UK.

    Science.gov (United States)

    Blades, Mabel

    2013-05-01

    Malnutrition is estimated to cost the UK twice that of obesity every year, but it is still an often overlooked problem. Dr Mabel Blades, a freelance Registered Dietician and Nutritionist, looks at the problems that malnutrition presents and the solutions that we can use to combat it.

  6. UK Mission to CERN

    CERN Multimedia

    2004-01-01

    At the end of June, nine experts from UK industry visited CERN to study techniques for developing distributed computing systems and to look at some specific applications. In a packed three-day programme, almost 40 CERN experts presented a comprehensive survey of achievements.

  7. Hewitt launches Research Councils UK

    CERN Multimedia

    2002-01-01

    "Trade and Industry Secretary Patricia Hewitt today launched 'Research Councils UK' - a new strategic partnership that will champion research in science, engineering and technology across the UK" (1 page).

  8. UK Royal Navy WWII Logbooks

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In 2006, the UK and NOAA's Climate Database Modernization Program (CDMP) funded the imaging of approximately 8,000 Royal Navy logbooks in the UK National Archives...

  9. Bottomley fuels fears London issues are too hot to handle.

    Science.gov (United States)

    1993-10-13

    Rumours that the government is shying away from tackling , the difficult issue of London's hospitals were fuelled by remarks made by Health Secretary Virginia Bottomley at a Conservative Party fringe meeting last week.

  10. Opinions from senior managers of London's luxury hotels

    African Journals Online (AJOL)

    jane.b

    consideration for hoteliers who are looking to open a luxury hotel within the city of London, ... the importance the spa plays to the hotel, its overall purpose of being in operation, .... market provide benefit by identifying different dynamics of.

  11. The Making of Two Readers: Agatha Christie and Jack London.

    Science.gov (United States)

    Baghban, Marcia

    1990-01-01

    Looks at the lives of two well-known writers to explore how diverse experiences produce literate adults. Discusses Agatha Christie and Jack London who used reading and writing to earn a living and to gain international reputations. (MG)

  12. The Growth Path and Future of London International Financial Center

    Institute of Scientific and Technical Information of China (English)

    李清娟

    2013-01-01

    London has grown up quickly to be a global financial center as a Phoenix in the past 100years,recorded history dating back to over 500 years ago.Though the financial services in London were berated to be "greedy"and as part of a giant casino led to the recession,this view was not accurate.London international financial center has become the core of the global financial industry,and played a crucial role in the development of the global economy.This article mainly discusses:the influence of London financial center on the world economy,the support to real economic development,the status of historical stages,and the development trend of the City.

  13. London house prices are power-law distributed

    CERN Document Server

    MacKay, Niall

    2010-01-01

    In this pilot study we explore the house price distributions for London, Manchester, Bristol, Newcastle, Birmingham and Leeds. We find Pareto (power law) behaviour in their upper tails, which is clearly distinct from lognormal behaviour in the cases of London and Manchester. We propose an index of Housing Wealth Inequality based on the Pareto exponent and analogous to the Gini coefficient, and comment on its possible uses.

  14. Eating fuet in London: From Autoethnography to Transnational Ethnography

    Directory of Open Access Journals (Sweden)

    Clara Rubio

    2017-08-01

    Full Text Available My own experience as a young Spanish migrant in London drove me to consider the importance that Spanish food has for emigrants and to consider its role within the community. This article presents food as a metaphor of the youth migration process to London during the economic crisis, and is based on three elements: how they construct their identity, their transition to adulthood and their condition as transmigrants.

  15. Assessing public health risk in the London polonium-210 incident, 2006.

    Science.gov (United States)

    Maguire, H; Fraser, G; Croft, J; Bailey, M; Tattersall, P; Morrey, M; Turbitt, D; Ruggles, R; Bishop, L; Giraudon, I; Walsh, B; Evans, B; Morgan, O; Clark, M; Lightfoot, N; Gilmour, R; Gross, R; Cox, R; Troop, P

    2010-06-01

    Mr Alexander Litvinenko died in a London hospital on 23 November 2006, allegedly from poisoning with the radionuclide polonium-210 ((210)Po). Associated circumstances required an integrated response to investigate the potential risk of internal contamination for individuals exposed to contaminated environments. Descriptive study. Contaminated locations presenting a potential risk to health were identified through environmental assessment by radiation protection specialists. Individuals connected with these locations were identified and assessed for internal contamination with (210)Po. In total, 1029 UK residents were identified, associated with the 11 most contaminated locations. Of these, 974 were personally interviewed and 787 were offered urine tests for (210)Po excretion. Overall, 139 individuals (18%) showed evidence of probable internal contamination with (210)Po arising from the incident, but only 53 (7%) had assessed radiation doses of 1mSv or more. The highest assessed radiation dose was approximately 100mSv. Although internal contamination with (210)Po was relatively frequent and was most extensive among individuals associated with locations judged a priori to pose the greatest risk, a high degree of assurance could be given to UK and international communities that the level of health risk from exposure to the radionuclide in this incident was low. Copyright 2010 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  16. Spectator Consumer Behaviors at the 2012 London Paralympic Games

    Directory of Open Access Journals (Sweden)

    Ridvan Ekmekci

    2013-01-01

    Full Text Available Although the Paralympics are the world’s second largest sporting event after the Olympics and continue to grow in popularity, there is little available research regarding spectators of sport competitions for disabled athletes. The purpose of this study was to profile spectators’ consumer behaviors in order to understand what factors explain spectators’ spending, length of stay, and attendance at the London Paralympic Games. Data was collected in a six-day period from a sample of 504 people present in London at three Paralympic sport facilities during the 2012 Paralympic Games. The results of the regression analyses revealed that nationality, attended contests, group size, having a connection with a Paralympic athlete, length of stay, gender and London Olympics’ spectators were significant determinants of Paralympics spectators’ spending in London. The data also indicated that spending, being from England (or not, gender, and being a friend/relative of a Paralympic athlete significantly affected spectators’ length of stay in London. Additionally, spectators’ attendance at the London Paralympic contests was predicted by spending, the size of the travel group, Beijing Paralympics’ spectators and age.

  17. Satisfaction with inpatient treatment for first-episode psychosis among different ethnic groups: A report from the UK AeSOP study.

    LENUS (Irish Health Repository)

    Boydell, Jane

    2010-09-17

    BACKGROUND: There is concern about the level of satisfaction with mental healthcare among minority ethnic patients in the UK, particularly as black patients have more compulsory admissions to hospital. AIMS: To determine and compare levels of satisfaction with mental healthcare between patients from different ethnic groups in a three-centre study of first-onset psychosis. METHOD: Data were collected from 216 patients with first-episode psychosis and 101 caregivers from South London, Nottingham and Bristol, using the Acute Services Study Questionnaire (Patient and Relative Version) and measures of sociodemographic variables and insight. RESULTS: No differences were found between ethnic groups in most domains of satisfaction tested individually, including items relating to treatment by ward staff and number of domains rated as satisfactory. However, logistic regression modelling (adjusting for age, gender, social class, diagnostic category and compulsion) showed that black Caribbean patients did not believe that they were receiving the right treatment and were less satisfied with medication than white patients. Black African patients were less satisfied with non-pharmacological treatments than white patients. These findings were not explained by lack of insight or compulsory treatment. CONCLUSIONS: The study found that black patients were less satisfied with specific aspects of treatment, particularly medication, but were equally satisfied with nursing and social care. Understanding the reasons behind this may improve the acceptability of psychiatric care to black minority ethnic groups.

  18. The Well London program - a cluster randomized trial of community engagement for improving health behaviors and mental wellbeing: baseline survey results

    Directory of Open Access Journals (Sweden)

    Phillips Gemma

    2012-07-01

    Full Text Available Abstract Background The Well London program used community engagement, complemented by changes to the physical and social neighborhood environment, to improve physical activity levels, healthy eating, and mental wellbeing in the most deprived communities in London. The effectiveness of Well London is being evaluated in a pair-matched cluster randomized trial (CRT. The baseline survey data are reported here. Methods The CRT involved 20 matched pairs of intervention and control communities (defined as UK census lower super output areas (LSOAs; ranked in the 11% most deprived LSOAs in London by the English Indices of Multiple Deprivation across 20 London boroughs. The primary trial outcomes, sociodemographic information, and environmental neighbourhood characteristics were assessed in three quantitative components within the Well London CRT at baseline: a cross-sectional, interviewer-administered adult household survey; a self-completed, school-based adolescent questionnaire; a fieldworker completed neighborhood environmental audit. Baseline data collection occurred in 2008. Physical activity, healthy eating, and mental wellbeing were assessed using standardized, validated questionnaire tools. Multiple imputation was used to account for missing data in the outcomes and other variables in the adult and adolescent surveys. Results There were 4,107 adults and 1,214 adolescent respondents in the baseline surveys. The intervention and control areas were broadly comparable with respect to the primary outcomes and key sociodemographic characteristics. The environmental characteristics of the intervention and control neighborhoods were broadly similar. There was greater between-cluster variation in the primary outcomes in the adult population compared to the adolescent population. Levels of healthy eating, smoking, and self-reported anxiety/depression were similar in the Well London adult population and the national Health Survey for England. Levels of

  19. Virtual particle therapy centre

    CERN Multimedia

    2015-01-01

    Particle therapy is an advanced technique of cancer radiation therapy, using protons or other ions to target the cancerous mass. This advanced technique requires a multi-disciplinary team working in a specialised centre. 3D animation: Nymus3D

  20. The IGU Knowledge Centre

    NARCIS (Netherlands)

    Huizing, Bernardus

    2005-01-01

    This article describes an innovative service for members of the International Gas Union - IGU. The IGU Knowledge Centre provides members with relevant information and data. In this article is described why, how and where.

  1. CENTRE FOR GEOMETRICAL METROLOGY

    DEFF Research Database (Denmark)

    De Chiffre, Leonardo

    The objective of this Annual Report is to give a general introduction to CGM as well as to give an account of the tasks carried out using the facilities of CGM's Instrument Centre during 1998 and 1999....

  2. Accessible by design: Library Search at the University of the Arts London

    Directory of Open Access Journals (Sweden)

    Karen Carden

    2016-07-01

    Full Text Available This brief case study, originally presented as a breakout session by Sandra Reed and Sara Osman at the UKSG Annual Conference in April 2016,1 outlines how the University of the Arts London put accessibility at the centre of its new open source library catalogue ‘Library Search’. It discusses how accessibility and inclusive design were prioritized throughout the initial discovery process and during engagement with students and other stakeholders, and how our requirement for accessibility was enhanced by the procurement method chosen. The article also considers how practical elements of good, accessible design are an integral part of the new interface. Our broader service offer and plans for the future are also included.

  3. The Prediction of Disruptive Behaviour Disorders in an Urban Community Sample: The Contribution of Person-Centred Analyses

    Science.gov (United States)

    Burt, Keith B.; Hay, Dale F.; Pawlby, Susan; Harold, Gordon; Sharp, Deborah

    2004-01-01

    Background: Variable- and person-centred analyses were used to examine prediction of middle childhood behaviour problems from earlier child and family measures. Method: A community sample of 164 families, initially recruited at antenatal clinics at two South London practices, was assessed for children's behaviour problems and cognitive ability,…

  4. Combined Ground and Space-Based Measurements of Air Quality during the London Olympic Games 2012

    Science.gov (United States)

    Graves, R. R.; Leigh, R. J.; Singh Anand, J.; McNally, M.; Lawrence, J.; Remedios, J.; Monks, P. S.

    2012-12-01

    During July and August 2012 the Summer Olympic Games were held in London. During this period, unusually high levels of traffic and visitors to the city were expected, it is important to understand the effect this had on the air quality in London during this period. To this end three novel CityScan instruments were installed in London from the 20th July though to the end of September; affording the unique opportunity to monitor the spatial and vertical structure of nitrogen dioxide within the boundary layer in unprecedented detail. The deployment was included as part of the large NERC funded ClearfLo project (Clean Air for London) involving many other institutions and complementary measurement techniques. CityScan is a Hemispherical Scanning Imaging Differential Optical Absorption Spectrometer (HSI-DOAS) which is has been optimised to measure concentrations of nitrogen dioxide. CityScan has a 95° field of view (FOV) between the zenith and 5° below the horizon. Across this FOV there are 128 resolved elements which are measured concurrently, the spectrometer is rotated azimuthally 1° per second providing full hemispherical coverage every 6 minutes. CityScan measures concentrations of nitrogen dioxide over specific lines of sight and due to the extensive field of view of the instrument this produces measurements which are representative over city-wide scales. Nitrogen dioxide is an important air pollutant which is produced in all combustion processes and can reduce lung function; especially in sensitised individuals. These instruments aim to bridge the gap in spatial scales between point source measurements of air quality and satellite measurements of air quality offering additional information on emissions, transport and the chemistry of nitrogen dioxide. More information regarding the CityScan technique can be found at http://www.leos.le.ac.uk/aq/index.html. The first of the three CityScan instruments was located in North Kensington, the second in Soho and third

  5. Current status of kilovoltage (kV) radiotherapy in the UK: installed equipment, clinical workload, physics quality control and radiation dosimetry.

    Science.gov (United States)

    Palmer, Antony L; Pearson, Michael; Whittard, Paul; McHugh, Katie E; Eaton, David J

    2016-12-01

    To assess the status and practice of kilovoltage (kV) radiotherapy in the UK. 96% of the radiotherapy centres in the UK responded to a comprehensive survey. An analysis of the installed equipment base, patient numbers, clinical treatment sites, quality control (QC) testing and radiation dosimetry processes were undertaken. 73% of UK centres have at least one kV treatment unit, with 58 units installed across the UK. Although 35% of units are over 10 years old, 39% units have been installed in the last 5 years. Approximately 6000 patients are treated with kV units in the UK each year, the most common site (44%) being basal cell carcinoma. A benchmark of QC practice in the UK is presented, against which individual centres can compare their procedures, frequency of testing and acceptable tolerance values. We propose the use of internal "notification" and "suspension" levels for analysis. All surveyed centres were using recommended Codes of Practice for kV dosimetry in the UK; approximately the same number using in-air and in-water methodologies for medium energy, with two-thirds of all centres citing "clinical relevance" as the reason for choice of code. 64% of centres had hosted an external dosimetry audit within the last 3 years, with only one centre never being independently audited. The majority of centres use locally measured applicator factors and published backscatter factors for treatments. Monitor unit calculations are performed using software in only 36% of centres. A comprehensive review of current kV practice in the UK is presented. Advances in knowledge: Data and discussion on contemporary kV radiotherapy in the UK, with a particular focus on physics aspects.

  6. Renal artery sympathetic denervation: observations from the UK experience

    OpenAIRE

    Sharp, Andrew S. P.; Davies, Justin E.; Lobo, Melvin D.; Bent, Clare L.; Mark, Patrick B.; Burchell, Amy E; Thackray, Simon D.; Martin, Una; McKane, William S.; Gerber, Robert T.; Wilkinson, James R.; Antonios, Tarek F.; Doulton, Timothy W.; Patterson, Tiffany; Clifford, Piers C.

    2016-01-01

    Background Renal denervation (RDN) may lower blood pressure (BP); however, it is unclear whether medication changes may be confounding results. Furthermore, limited data exist on pattern of ambulatory blood pressure (ABP) response—particularly in those prescribed aldosterone antagonists at the time of RDN. Methods We examined all patients treated with RDN for treatment-resistant hypertension in 18 UK centres. Results Results from 253 patients treated with five technologies are shown. Pre-proc...

  7. Bottling plant location of microbreweries in East Midlands area, UK

    OpenAIRE

    Zheng, Chi

    2013-01-01

    Facility location decisions are critical in real-life projects, which impact on profitability of investment and service levels from demand side. In this paper, a project-based facility location problem should be resolved which refers to the establishment of a centralized bottling plant to serve microbreweries in East Midlands area of UK. This problem will be structured by firstly finding a mathematically theoretical location using the centre-of-gravity method and then formulate the problem as...

  8. The UK Human Genome Mapping Project online computing service.

    Science.gov (United States)

    Rysavy, F R; Bishop, M J; Gibbs, G P; Williams, G W

    1992-04-01

    This paper presents an overview of computing and networking facilities developed by the Medical Research Council to provide online computing support to the Human Genome Mapping Project (HGMP) in the UK. The facility is connected to a number of other computing facilities in various centres of genetics and molecular biology research excellence, either directly via high-speed links or through national and international wide-area networks. The paper describes the design and implementation of the current system, a 'client/server' network of Sun, IBM, DEC and Apple servers, gateways and workstations. A short outline of online computing services currently delivered by this system to the UK human genetics research community is also provided. More information about the services and their availability could be obtained by a direct approach to the UK HGMP-RC.

  9. Patient assessment of an electronic device for subcutaneous self-injection of interferon ß-1a for multiple sclerosis: an observational study in the UK and Ireland

    Directory of Open Access Journals (Sweden)

    D'Arcy C

    2012-01-01

    Full Text Available Caroline D’Arcy1, Del Thomas2, Dee Stoneman3, Laura Parkes31West London Neuroscience Centre, Charing Cross Hospital, London, UK; 2Wye Valley NHS Trust, Hereford, UK; 3Merck Serono Ltd, Feltham, Middlesex, UKBackground: Injectable disease-modifying drugs (DMDs reduce the number of relapses and delay disability progression in patients with relapsing–remitting multiple sclerosis (RRMS. Regular self-injection can be stressful and impeded by MS symptoms. Auto-injection devices can simplify self-injection, overcome injection-related issues, and increase treatment satisfaction. This study investigated patient responses to an electronic auto-injection device.Methods: Patients with RRMS (n = 63, aged 18–65 years, naïve to subcutaneous (sc interferon (IFN ß-1a therapy, were recruited to a Phase IV, observational, open-label, multicenter study (NCT01195870. Patients self-injected sc IFN ß-1a using the RebiSmart™ (Merck Serono S.A. – Geneva, Switzerland electronic auto-injector for 12 weeks, including an initial titration period if recommended by the prescribing physician. In week 12, patients completed a questionnaire comprising of a visual analog scale (VAS to rate how much they liked using the device, a four-point response question on ease of use (‘very difficult’, ‘difficult’, ‘easy’, or ‘very easy’, and a list of ten device functions to rank, based upon their experiences.Results: Six patients (9.5% discontinued the study: one switched to manual injection; two discontinued all treatment; three changed therapy. In total, 59 out of 63 patients (93.7% completed the VAS; 54 out of 59 (91.5%; 95% confidence interval: 81.3%–97.2% ‘liked’ using the electronic auto-injector (score ≥6, whereas 57 out of 59 (96.6% rated the device overall as ‘easy’ or ‘very easy’ to use. Device features rated as most useful were the hidden needle (mean [standard deviation] score: 3.3 [3.01]; n = 56, confirmation sound (3.9 [2.45], and

  10. Life satisfaction and air quality in London

    Energy Technology Data Exchange (ETDEWEB)

    MacKerron, George; Mourato, Susana [Department of Geography and Environment, and Grantham Research Institute on Climate Change and the Environment, London School of Economics and Political Science, Houghton Street, London WC2A 2AE (United Kingdom)

    2009-03-15

    A growing body of research in economics concerns self-reported happiness, or life satisfaction (LS), and its relationship to a wide range of other variables. The findings of this research tend to highlight the importance of non-income aspects of individuals' life conditions. These findings are strongly complementary to themes within the sustainable development discourse. Firstly, they suggest ways in which we might consume less without compromising on our current levels of LS. And secondly, they help demonstrate the immediate LS benefits that could be gained from higher levels of environmental quality (EQ). However, the empirical evidence for the link between EQ and LS is, to date, somewhat weak, due in part to a lack of EQ data at a level of detail to match the individual-by-individual resolution of LS measures. This small, exploratory study therefore seeks to assess how the use of EQ data at very high spatial resolution could advance the empirical literature examining connections between LS and EQ levels, focusing on air quality in particular. It collects original survey data for approximately 400 Londoners, and uses geographical information system (GIS) software to calculate pollutant concentrations in the immediate vicinity of their homes. It uses this data to estimate maximum likelihood regression models explaining LS ratings in terms of a range of individual, household and local variables. Both perceived and measured air pollution levels are significantly negatively associated with the LS of the survey respondents, even when controlling for a wide range of other effects. An increase of 10 {mu}g/m{sup 3} in annual mean nitrogen dioxide concentration appears to correspond on average to a drop of nearly half a point of LS on an 11-point rating scale. These findings cannot yet be generalised with confidence. However, if they were confirmed by larger future studies, they would appear to strengthen and extend existing arguments in favour of policies to reduce

  11. Global sport mega-events and the politics of mobility: the case of the London 2012 Olympics.

    Science.gov (United States)

    Giulianotti, Richard; Armstrong, Gary; Hales, Gavin; Hobbs, Dick

    2015-03-01

    This paper examines the politics of mobility which surrounded the London 2012 Olympics. We provide a critical discussion of the mobility conflicts, problems and criticisms which emerged from our research with local people in the Stratford and wider Newham areas of London, where most Olympic events were located. The paper is divided into four broad parts. First, we identify and discuss the relevant components of the 'mobilities paradigm' in social science which underpin our analysis. Second, we briefly outline our research methods, centring particularly on fieldwork and interviews with different social groups. Third, we examine in detail the six main themes of mobility politics which were evident at London 2012, relating to social context, event construction, event mobility systems, commercial mobilities, the mobile politics of exclusion, and contested modes of mobility. In doing so, we seek to extend the mobilities paradigm by introducing various concepts and keywords - notably on the three-speed city, entryability, mobility panics, instrumental mobility, and corporate kettling - which may be utilized by social scientists to examine mobility systems in other social contexts. We conclude by reaffirming the significance of mobility-focused research at sport and other mega-events, and by indicating future lines of inquiry for social scientists.

  12. Assessment of the impact of the London Olympics 2012 on selected non-genitourinary medicine clinic sexual health services.

    Science.gov (United States)

    Hartley, A; Foster, R; Brook, M G; Cassell, J A; Mercer, C H; Coyne, K; Hughes, G; Crook, P

    2015-04-01

    With minimal information on sexual health provision during mass-gathering events, our aim was to describe the use of sexual health, contraceptive, sex worker and sexual assault services during the London 2012 Olympics. We analysed data from five sources. One contraceptive service provider reported a 10% increase in attendance during the main Games, while emergency contraception prescriptions rose during the main Olympics, compared to the week before, but were similar or lower than at the beginning and end of the summer period. A health telephone advice line reported a 16% fall in sexual health-related calls during the main Olympics, but a 33% increase subsequently. London sexual assault referral centres reported that 1.8% of sexual assaults were Olympics-linked. A service for sex workers reported that 16% started working in the sex industry and 7% moved to London to work during the Olympics. Fifty-eight per cent and 45% of sex workers reported fewer clients and an increase in police crack-downs, respectively. Our results show a change in activity across these services during the 2012 summer, which may be associated with the Olympics. Our data are a guide to other services when anticipating changes in service activity and planning staffing for mass-gathering events.

  13. Provision of health promotion programmes to people with serious mental illness: a mapping exercise of four South London boroughs.

    Science.gov (United States)

    O'Brien, C; Gardner-Sood, P; Corlett, S K; Ismail, K; Smith, S; Atakan, Z; Greenwood, K; Joseph, C; Gaughran, F

    2014-03-01

    People with serious mental illness (SMI) are at increased risk of developing various physical health diseases, contributing to significantly reduced life expectancies compared with the general population. In light of this, the Department of Health have set the physical health of people with mental health problems as a priority for improvement. Additionally, the UK government encourages the NHS and local authorities to develop health promotion programmes (HPPs) for people with SMI. To document how many and what types of HPPs were available to people with SMI across four South London boroughs, UK. We found 145 HPPs were available to people with SMI across the four boroughs, but with an inequitable distribution. We also found that certain HPPs set admission criteria that were likely to act as a barrier to improving health. A more integrated approach of documenting and providing information regarding the provision of HPPs for or inclusive of people with SMI is needed. People with serious mental illness (SMI) such as schizophrenia, schizoaffective disorders and bipolar disorder are at increased risk of developing diabetes, cardiovascular disease and respiratory disease, contributing to significantly reduced life expectancies. As a result, emphasis has been placed on developing Health Promotion Programmes (HPPs) to modify the risk of poor physical health in SMI. We examined how many and what types of HPPs are available for or inclusive of people with SMI across four borough in South London, UK. A cross-sectional mapping study was carried out to identify the number of HPPs available to people with SMI. We found 145 HPPs available to people with SMI existed across the four boroughs but with an inequitable distribution, which in some boroughs we anticipate may not meet need. In some cases, HPPs set admission conditions which were likely to further impede access. We recommend that accurate and readily available information on the provision of HPPs for or inclusive of people

  14. Exhaust system-related burns affecting children: a UK perspective and literature review

    OpenAIRE

    Vermaak, P.V.; Deall, C.E.; McArdle, C; Burge, T.

    2016-01-01

    Burns caused by exhaust systems in children may be associated with considerable morbidity. Current epidemiological data varies, but no data are available for the UK population. We aim to identify the pattern of exhaust-related burns affecting children who presented to a regional centre for paediatric burn care in the UK. Patients who sustained burns related to exhaust mechanisms between May 2005 and August 2012 were identified via the departmental database. Data collected included patient dem...

  15. Graduates of different UK medical schools show substantial differences in performance on MRCP(UK Part 1, Part 2 and PACES examinations

    Directory of Open Access Journals (Sweden)

    Mollon Jennifer

    2008-02-01

    Full Text Available Abstract Background The UK General Medical Council has emphasized the lack of evidence on whether graduates from different UK medical schools perform differently in their clinical careers. Here we assess the performance of UK graduates who have taken MRCP(UK Part 1 and Part 2, which are multiple-choice assessments, and PACES, an assessment using real and simulated patients of clinical examination skills and communication skills, and we explore the reasons for the differences between medical schools. Method We perform a retrospective analysis of the performance of 5827 doctors graduating in UK medical schools taking the Part 1, Part 2 or PACES for the first time between 2003/2 and 2005/3, and 22453 candidates taking Part 1 from 1989/1 to 2005/3. Results Graduates of UK medical schools performed differently in the MRCP(UK examination between 2003/2 and 2005/3. Part 1 and 2 performance of Oxford, Cambridge and Newcastle-upon-Tyne graduates was significantly better than average, and the performance of Liverpool, Dundee, Belfast and Aberdeen graduates was significantly worse than average. In the PACES (clinical examination, Oxford graduates performed significantly above average, and Dundee, Liverpool and London graduates significantly below average. About 60% of medical school variance was explained by differences in pre-admission qualifications, although the remaining variance was still significant, with graduates from Leicester, Oxford, Birmingham, Newcastle-upon-Tyne and London overperforming at Part 1, and graduates from Southampton, Dundee, Aberdeen, Liverpool and Belfast underperforming relative to pre-admission qualifications. The ranking of schools at Part 1 in 2003/2 to 2005/3 correlated 0.723, 0.654, 0.618 and 0.493 with performance in 1999–2001, 1996–1998, 1993–1995 and 1989–1992, respectively. Conclusion Candidates from different UK medical schools perform differently in all three parts of the MRCP(UK examination, with the

  16. Exploring anterograde associative memory in London taxi drivers.

    Science.gov (United States)

    Woollett, Katherine; Maguire, Eleanor A

    2012-10-24

    London taxi drivers are renowned for their navigation ability, spending a number of years acquiring 'The Knowledge' of London's complex layout and having to pass stringent examinations to obtain an operating licence. In several studies, this navigation skill has been associated with increased posterior but also decreased anterior hippocampal grey matter volume. Neuropsychologically, gain and loss has also been documented in taxi drivers; while very skilled at navigation in London, they are significantly poorer than controls at learning and recalling new object-location associations. Here we tested a group of London taxi drivers and matched control participants on this object-location associations task, while also subjecting them to a battery of challenging anterograde associative memory tests involving verbal, visual and auditory material both within and across modalities. Our aim was to assess whether their difficulty in previous studies reflected a general problem with associative memory, or was restricted to the spatial domain. We replicated previous findings of poor learning and memory of object-location associations. By contrast, their performance on the other anterograde associative memory tasks was comparable with controls. This resolves an outstanding question in the memory profile of London taxi drivers following hippocampal plasticity, and underlines the close relationship between space and the hippocampus.

  17. Introduction: Andrew Thomson and the Centre for Metalloprotein Spectroscopy and Biology at the University of East Anglia.

    Science.gov (United States)

    Wilson, Michael T

    2008-12-01

    The present article briefly relates the early history and growth of the Centre for Metalloprotein Spectroscopy and Biology at UEA (University of East Anglia) under the joint directorship of A.J. Thomson and C. Greenwood, and charts the exceptional success that this centre has had in fostering bioinorganic chemistry in the U.K. and the impact that it has had internationally.

  18. Virtual Visit to the ATLAS Control Room by London Academy

    CERN Multimedia

    2013-01-01

    London Academy is a multicultural academy in Edgware, outer London. Within an extremely caring and supportive environment, students, including those in the sixth form, many pupils, flourish and achieve well. The Principal`s clear vision of a learning community that develops in its students the skills and values that will enable them to live their lives as respectful, caring and responsible citizens is both shared and realised. The event was organised from London Academy by the Physics Teacher, Ms Pamela Chabba; the older science students, especially those who are studying pure physics, are very excited about the event linking them to CERN. They range between 14-18 years old and many plan to go on to study sciences at university.

  19. Learning as Social Exchange in City Year London

    DEFF Research Database (Denmark)

    Revsbech, Christine

    Learning as Social Exchange in City Year London: Action towards an image of greatness contributes to the growing field of research on social entrepreneurship. The thesis is the result of an interesting, anthropological study of a social voluntary organisation, City Year London, a British affiliate...... of an American charity. Young volunteers were followed in their daily activities working as mentors for public primary school children, and the interaction between staff and volunteers in City Year London were observed. Also, interviews with both volunteers and staff were carried out. The thesis explores...... the empirical findings applying an understanding of learning as social exchange of value. The rich empirical data has led to analyses that draw on and contribute to economic anthropology, learning theories and social entrepreneurship....

  20. Multifractal to monofractal evolution of the London's street network

    CERN Document Server

    Murcio, Roberto; Arcaute, Elsa; Batty, Michael

    2015-01-01

    We perform a multifractal analysis of the evolution of London's street network from 1786 to 2010. First, we show that a single fractal dimension, commonly associated with the morphological description of cities, does not su ce to capture the dynamics of the system. Instead, for a proper characterization of such a dynamics, the multifractal spectrum needs to be considered. Our analysis reveals that London evolves from an inhomogeneous fractal structure, that can be described in terms of a multifractal, to a homogeneous one, that converges to monofractality. We argue that London's multifractal to monofracal evolution might be a special outcome of the constraint imposed on its growth by a green belt. Through a series of simulations, we show that multifractal objects, constructed through di usion limited aggregation, evolve towards monofractality if their growth is constrained by a non-permeable boundary.

  1. The future of the London Buy-To-Let property market: Simulation with temporal Bayesian Networks

    Science.gov (United States)

    Fenton, Norman

    2017-01-01

    In 2015 the British government announced a number of major tax reforms for individual landlords. To give landlords time to adjust, some of these tax measures are being introduced gradually from April 2017, with full effect in tax year 2020/21. The changes in taxation have received much media attention since there has been widespread belief that the new measures were sufficiently skewed against landlords that they could signal the end of the Buy-To-Let (BTL) investment era in the UK. This paper assesses the prospective performance of BTL investments in London from the investor’s perspective, and examines the impact of incoming tax reforms using a novel Temporal Bayesian Network model. The model captures uncertainties of interest by simulating the impact of changing circumstances and the interventions available to an investor at various time-steps of a BTL investment portfolio. The simulation results suggest that the new tax reforms are likely to have a detrimental effect on net profits from rental income, and this hits risk-seeking investors who favour leverage much harder than risk-averse investors who do not seek to expand their property portfolio. The impact on net profits also poses substantial risks for lossmaking returns excluding capital gains, especially in the case of rising interest rates. While this makes it less desirable or even non-viable for some to continue being a landlord, based on the current status of all factors taken into consideration for simulation, investment prospects are still likely to remain good within a reasonable range of interest rate and capital growth rate variations. The results also suggest that the recent trend of property prices in London increasing faster than rents will not continue for much longer; either capital growth rates will have to decrease, rental growth rates will have to increase, or we shall observe a combination of the two events. PMID:28654698

  2. The future of the London Buy-To-Let property market: Simulation with temporal Bayesian Networks.

    Science.gov (United States)

    Constantinou, Anthony C; Fenton, Norman

    2017-01-01

    In 2015 the British government announced a number of major tax reforms for individual landlords. To give landlords time to adjust, some of these tax measures are being introduced gradually from April 2017, with full effect in tax year 2020/21. The changes in taxation have received much media attention since there has been widespread belief that the new measures were sufficiently skewed against landlords that they could signal the end of the Buy-To-Let (BTL) investment era in the UK. This paper assesses the prospective performance of BTL investments in London from the investor's perspective, and examines the impact of incoming tax reforms using a novel Temporal Bayesian Network model. The model captures uncertainties of interest by simulating the impact of changing circumstances and the interventions available to an investor at various time-steps of a BTL investment portfolio. The simulation results suggest that the new tax reforms are likely to have a detrimental effect on net profits from rental income, and this hits risk-seeking investors who favour leverage much harder than risk-averse investors who do not seek to expand their property portfolio. The impact on net profits also poses substantial risks for lossmaking returns excluding capital gains, especially in the case of rising interest rates. While this makes it less desirable or even non-viable for some to continue being a landlord, based on the current status of all factors taken into consideration for simulation, investment prospects are still likely to remain good within a reasonable range of interest rate and capital growth rate variations. The results also suggest that the recent trend of property prices in London increasing faster than rents will not continue for much longer; either capital growth rates will have to decrease, rental growth rates will have to increase, or we shall observe a combination of the two events.

  3. Epidemiology of internal contamination with polonium-210 in the London incident, 2006.

    Science.gov (United States)

    Fraser, G; Giraudon, I; Cohuet, S; Bishop, L; Maguire, H; Thomas, H L; Mandal, S; Anders, K; Sanchez-Padilla, E; Charlett, A; Evans, B; Gross, R

    2012-02-01

    More than 700 UK residents were tested for possible contamination with polonium-210 ((210)Po) following the alleged poisoning of Mr Alexander Litvinenko in London in November 2006. This paper describes the epidemiology of internal contamination with the radionuclide in this group. 11 locations in London had been identified as sufficiently environmentally contaminated with (210)Po to present a health risk to people associated with them. Public health consultant teams identified individuals at risk and offered 24-h urine testing for (210)Po excretion. Prevalence of internal contamination was estimated, and a retrospective cohort analysis was completed for each location. Overall 139 individuals (prevalence 0.19 (95% CI 0.13 to 0.27)) showed evidence of internal contamination with (210)Po, although none with uptakes likely to cause adverse health effects. Substantial prevalence was seen among specific hotel service staff, customers, staff and other users of a hotel bar, office and hospital staff, staff of one restaurant and residents of and visitors to the family home. Increased risks of contamination were seen for a hotel bar in association with occupational, behavioural and temporal factors. Occupational and guest exposure to contaminated areas of hotels were also associated with increased contamination risk. Nurses were more likely to become contaminated than other staff involved in direct patient care. Uptake of trace amounts of radionuclide in this incident was frequent. Occupational, behavioural and temporal gradients in contamination risk were mostly consistent with a priori site risk assessments. Utility of the investigation methods and findings for future accidental or deliberate environmental contamination incidents are discussed.

  4. UK maritime developments

    Energy Technology Data Exchange (ETDEWEB)

    Cappuccaio, M.

    2005-05-01

    Global maritime trade continues to expand in 2003. UNCTAD estimated over 6 Bn/t (billion tonnes) of dry bulk raw materials, oil, oil products and manufactured good were shipped by sea in 2003, recording a 3.7% annual growth rate with similarly healthy growth projected for 2004 and 2005. The expansion is mainly attributable to the economic performance of the US, Japan and China and, to a lesser extent, Europe. The article gives the latest news on developments at UK ports and contains statistics on port traffic and cargo. A table gives figures for coal handled by major ports from 2001 to 2003. 7 tabs., 2 photos.

  5. Academic Drug Discovery Centres

    DEFF Research Database (Denmark)

    Kirkegaard, Henriette Schultz; Valentin, Finn

    2014-01-01

    Academic drug discovery centres (ADDCs) are seen as one of the solutions to fill the innovation gap in early drug discovery, which has proven challenging for previous organisational models. Prior studies of ADDCs have identified the need to analyse them from the angle of their economic...... their performance....

  6. CENTRE IN NIGERIA.

    African Journals Online (AJOL)

    PATTERN OF NEURO-OPHTHALMIC DISORDERS IN A TERTIARY EYE. CENTRE IN NIGERIA. A E Omoti , M J M ... movement or light was determined. The external ... assessed by color desaturation tests and visual field assessment by the ...

  7. Implementing Responsibility Centre Budgeting

    Science.gov (United States)

    Vonasek, Joseph

    2011-01-01

    Recently, institutes of higher education (universities) have shown a renewed interest in organisational structures and operating methodologies that generate productivity and innovation; responsibility centre budgeting (RCB) is one such process. This paper describes the underlying principles constituting RCB, its origin and structural elements, and…

  8. The GSO Data Centre

    CERN Document Server

    Paletou, F; Génot, V; Rouillard, A; Petit, P; Palacios, A; Caux, E; Wakelam, V

    2015-01-01

    Hereafter we describe the activities of the $Grand \\, Sud-Ouest$ Data Centre operated for INSU/CNRS by the OMP-IRAP and the Universit\\'e Paul Sabatier (Toulouse), in a collaboration with the OASU-LAB (Bordeaux) and OREME-LUPM (Montpellier).

  9. Implementing Responsibility Centre Budgeting

    Science.gov (United States)

    Vonasek, Joseph

    2011-01-01

    Recently, institutes of higher education (universities) have shown a renewed interest in organisational structures and operating methodologies that generate productivity and innovation; responsibility centre budgeting (RCB) is one such process. This paper describes the underlying principles constituting RCB, its origin and structural elements, and…

  10. ATLAS Visitors Centre

    CERN Multimedia

    claudia Marcelloni

    2009-01-01

    ATLAS Visitors Centre has opened its shiny new doors to the public. Officially launched on Monday February 23rd, 2009, the permanent exhibition at Point 1 was conceived as a tour resource for ATLAS guides, and as a way to preserve the public’s opportunity to get a close-up look at the experiment in action when the cavern is sealed.

  11. Algebra of the Visual: The London Underground Map and the Art It Has Inspired

    Directory of Open Access Journals (Sweden)

    Alan Ashton-Smith

    2011-01-01

    Full Text Available "Algebra of the Visual: The London Underground Map and the Art It Has Inspired" by Alan Ashton-Smith. The London Underground symbolizes London, and the London Underground map, designed by Harry Beck in 1931, symbolizes the London Underground. Accordingly, Beck’s map has in itself come to be a recognizable signifier of London. Its impact resonates beyond this city though: it is also the prototype for metro maps worldwide, with its basic topological structure having been adopted for use on the subways of many other cities. (NANO: New American Notes Online

  12. Investigating the annual behaviour of submicron secondary inorganic and organic aerosols in London

    Directory of Open Access Journals (Sweden)

    D. E. Young

    2014-07-01

    Full Text Available For the first time, the behaviour of non-refractory inorganic and organic submicron particulate through an entire annual cycle is investigated using measurements from an Aerodyne compact time-of-flight aerosol mass spectrometer (cToF-AMS located at a UK urban background site in North Kensington, London. We show secondary aerosols account for a significant fraction of the submicron aerosol burden and that high concentration events are governed by different factors depending on season. Furthermore, we demonstrate that on an annual basis there is no variability in the extent of secondary organic aerosol (SOA oxidation, as defined by the oxygen content, irrespective of amount. This result is surprising given the changes in precursor emissions and contributions as well as photochemical activity throughout the year; however it may make the characterisation of SOA in urban environments more straightforward than previously supposed. Organic species, nitrate, sulphate, ammonium, and chloride were measured during 2012 with average concentrations (±one standard deviation of 4.32 (±4.42, 2.74 (±5.00, 1.39 (±1.34, 1.30 (±1.52 and 0.15 (±0.24 μg m–3, contributing 43, 28, 14, 13 and 2% to the total submicron mass, respectively. Components of the organic aerosol fraction are determined using positive matrix factorisation (PMF where five factors are identified and attributed as hydrocarbon-like OA (HOA, cooking OA (COA, solid fuel OA (SFOA, type 1 oxygenated OA (OOA1, and type 2 oxygenated OA (OOA2. OOA1 and OOA2 represent more and less oxygenated OA with average concentrations of 1.27 (±1.49 and 0.14 (±0.29 μg m–3, respectively, where OOA1 dominates the SOA fraction (90%. Diurnal, monthly, and seasonal trends are observed in all organic and inorganic species, due to meteorological conditions, specific nature of the aerosols, and availability of precursors. Regional and transboundary pollution as well as other individual pollution events influence

  13. A Canadian model for building university and community partnerships: centre for research & education on violence against women and children.

    Science.gov (United States)

    Jaffe, Peter G; Berman, Helene; MacQuarrie, Barb

    2011-09-01

    The importance of Canadian research on violence against women became a national focus after the 1989 murder of 14 women at École Polytechnique in Montreal. This tragedy led to several federal government studies that identified a need to develop centers for applied research and community-university alliances on violence against women. One such center is the Centre for Research & Education on Violence against Women and Children. The Centre was founded in London, Canada in 1992 out of a partnership of a university, a community college, and community services. The centre's history and current activities are summarized as a model for the development and sustainability of similar centers.

  14. Training science centre Explainers. The Techniquest experience

    Directory of Open Access Journals (Sweden)

    Colin Johnson

    2005-12-01

    Full Text Available Techniquest was established in 1986, and in 1995 moved to its current premises at Cardiff Bay, South Wales. This was the first purpose-built science centre in the UK. It receives around 200,000 visitors every year to its exhibition, and to its programmes for schools and public audiences in the theatre, laboratory, discovery room and planetarium. The author joined the Techniquest project in 1985, became a staff member in 1990 and was the Chief Executive from 1997 until his retirement in 2004. Techniquest has three “out-stations” in Wales, and is responsible for the supply and maintenance of exhibits to the Look Out Discovery Centre in Bracknell, England. There is a Techniquest gallery at the Lisbon Pavilhão do Conhecimento - Ciência Viva, and a traveling exhibition, SciQuest, in South Africa which was also supplied by Techniquest. All these centres rely on the effective intervention of “Explainers” (at Techniquest we call them “Helpers” to provide the best possible experience for visitors. At its most demanding, the tasks of an Explainer are varied and intensive, yet there may be times when the duties are mundane or even dull. When you rely on people to act as both hosts and housekeepers, to provide both support and stimulus, and to be both welcoming and watchful, you are asking a great deal. This article raises some of the issues concerned with the recruitment and retention of Explainers, their training and management, and the way in which their role is recognized and valued by the science centre as a whole.

  15. Organisational structure of liver transplantation in the UK.

    Science.gov (United States)

    Neuberger, James

    2015-07-01

    This review aims to outline the delivery of liver transplant services in the UK. Liver transplantation in the UK is based on seven designated transplant units serving a population of just over 60 million people. Nearly 900 liver transplants were done in 2013/2014. Potential deceased donors are identified and referred to centrally employed specialist nurses for obtaining family consent and for donor characterisation. Organs are retrieved by a National Organ Retrieval Service, based on seven abdominal and six cardiothoracic retrieval teams providing a 24/7 service which has shown to be capable of retrieving organs from up to ten donors a day. Donated organs are allocated first nationally to those who qualify for super-urgent listing. The next priority is for splitting livers, and if there is no suitable recipient or the liver is not suitable for splitting, then livers are offered first to the local centre; each centre has a designated donor zone, adjusted annually to ensure equity between the number of patients listed and the number of donors. The allocation scheme is being reviewed, and national schemes based on need, utility and benefit are being assessed. Outcomes are monitored by National Health Service Blood and Transplant (NHSBT), and if there is a possibility of adverse deviation, then further inquiries are made. Outcomes, both from listing and from transplantation, are published by the centre on the NHSBT website ( www.odt.nhs.uk ). NHSBT works closely with stakeholders primarily through the advisory groups with clinicians, patients, lay members and professional societies and aims to provide openness and transparency. The system for organ donation and delivery of liver transplant in the UK has developed and is now providing an effective and efficient service, but there remains room for improvement.

  16. An Open Access Source for the Study of Religion and the Law: The Proceedings of the Old Bailey: London's Central Criminal Court 1674-1913

    Directory of Open Access Journals (Sweden)

    Fred Guyette

    2008-11-01

    Full Text Available The work of theological librarians is in a state of rapid flux as collections of digitized texts become more widely available, and as theological education continues to shift from paper to a more electronic research environment. /The Proceedings of the/ /Old Bailey, London 1674-1913 /is a rich collection of court records, now freely available on the World Wide Web (http://www.oldbaileyonline.org.uk/ . The study of a small, but meaningful selection of texts from the /OBP/ shows how theological librarians can use this resource to advance the conversation between religion and law. Five examples are offered to indicate how this might be done.

  17. Town Centre Redevelopment Strategies

    DEFF Research Database (Denmark)

    Vagnby, Bo Hellisen

    as slum clearence and urban renewal. To a certain extent parallels are drawn to international experiences, especially where these are of such a nature that they can be assumed transferred to Danish connctions. Conclusively, the strategies are discussed in the light of the turn of Danish urban planning...... urban planning and design strategieswhich have been practised in most of the larger Danish towns: pedestrian streets, shopping centres, preservation of historic features, waterfronts, concentration of offices, conference and sports facilities, improvement og traffic and transport conditions as well...... during late years, where increased internationalisation is in focus and where it seems as if the social dimension of the town centre planning is slipping out of the hands of the urban planners....

  18. Elderly Care Centre

    Science.gov (United States)

    Wagiman, Aliani; Haja Bava Mohidin, Hazrina; Ismail, Alice Sabrina

    2016-02-01

    The demand for elderly centre has increased tremendously abreast with the world demographic change as the number of senior citizens rose in the 21st century. This has become one of the most crucial problems of today's era. As the world progress into modernity, more and more people are occupied with daily work causing the senior citizens to lose the care that they actually need. This paper seeks to elucidate the best possible design of an elderly care centre with new approach in order to provide the best service for them by analysing their needs and suitable activities that could elevate their quality of life. All these findings will then be incorporated into design solutions so as to enhance the living environment for the elderly especially in Malaysian context.

  19. The University College London Archive of Stuttered Speech (UCLASS)

    Science.gov (United States)

    Howell, Peter; Davis, Stephen; Bartrip, Jon

    2009-01-01

    Purpose: This research note gives details of 2 releases of audio recordings available from speakers who stutter that can be accessed on the Web. Method: Most of the recordings are from school-age children. These are available on the University College London Archive of Stuttered Speech (UCLASS) Web site, and information is provided about how to…

  20. Jack London and "the Call of the Wild"

    Institute of Scientific and Technical Information of China (English)

    徐晶

    2002-01-01

    The article vividly analyzes the characteristics of Jack London's writing theme that is the description of the con-flicts between nature and human. Based on the "call of the wild" and its hero Buck, It points out the author' s writingthoughts, that is strong will human show in their fight against nature.

  1. A fatal case of Lassa fever in London, January 2009.

    Science.gov (United States)

    Kitching, A; Addiman, S; Cathcart, S; Bischop, L; Krahé, D; Nicholas, M; Coakley, J; Lloyd, G; Brooks, T; Morgan, D; Turbitt, D

    2009-02-12

    In January 2009, the eleventh [corrected] case of Lassa fever imported to the United Kingdom was diagnosed in London. Risk assessment of 328 healthcare contacts with potential direct exposure to Lassa virus - through contact with the case or exposure to bodily fluids - was undertaken. No contacts were assessed to be at high risk of infection and no secondary clinical cases identified.

  2. JACK LONDON ETNÓLOGO AMATEUR DEL PUGILISMO

    Directory of Open Access Journals (Sweden)

    Loïc Wacquant

    2012-12-01

    Full Text Available De los relatos que Jack London ha consagrado al boxeo, A Piece of Steak es sin dudas aquel que merece hoy nuestra mayor atención, e incluso un lugar en el panteón de los textos literarios sobre el Noble Arte, y junto a él otros tres títulos...

  3. London tõukas New Yorgi troonilt / Kertu Ruus

    Index Scriptorium Estoniae

    Ruus, Kertu, 1977-

    2007-01-01

    Maailma finantskeskuste indeksi järgi on London tõuganud New Yorgi teisele kohale, neile järgnevad Hongkong, Singapur ja Zürich. Vt. samas: IPOd on USAs kokku kuivanud. Tabel: Londoni börsile tuli mullu rohkem firmasid

  4. The Maintenance of The London Underground Tube Tunnel Network

    Institute of Scientific and Technical Information of China (English)

    Gleig Frazer

    2004-01-01

    It is helpful to have a brief history of London Underground when considering any aspect of its maintenance or future development. The system has developed over more than 100 years and only comparatively recently come under the control of a single organisation. This partly explains the complexity that has resulted from differences in construction between lines. A brief History is accordingly appended to this presentation as Appendix B. The recent History outlines how Tube Lines have come to be involved with London Underground and explains a little of the reason for our existence. We are required to maintain and improve London Underground assets. Our performance has to be measurable and it follows that we need to know the current condition "value" of those assets. A large part of London Underground's infrastructure is tube tunnels some of which have not been fully assessed since they were first constructed in the 19th Century. They used materials whose physical and durability properties were not, at the time, fully understood; and they were designed on a very empirical basis if they were "designed" at all. Some shafts and other elements of the Tunnel Asset appeared to have been forgotten or lost when the Public Private Partnership (PPP) instigation procedures began in earnest in 1998. A major part of our current maintenance programme is thus to ascertain and agree the current condition and extent of approximately 178kilometres of tube tunnel asset that we are required to maintain and improve.

  5. A Multimodal Discourse Analysis of 2012 London Olympic Emblem

    Institute of Scientific and Technical Information of China (English)

    张瑞雪

    2012-01-01

    At present,communication is developing from mono-modality to multi-modality.The related study on multimodal discourse is becoming a hot issue.This paper will adopt the theory of Kress and van Leeuwen's visual grammar as the theoretical framework to analyze the 2012 London Olympic emblem,exploring the meanings hidden behind the visual images.

  6. 'ah famous citie' : women, writing, and early modern London

    NARCIS (Netherlands)

    Wilcox, Helen

    2010-01-01

    This article explores aspects of the textual relationship between women and early modern London by examining three verbal 'snapshots' of the city in works either written by women or focusing on women in their urban environment. The first text, Isabella Whitney's 'Wyll and Testament' (1573), addresse

  7. Intergenerational Learning between Children and Grandparents in East London

    Science.gov (United States)

    Kenner, Charmian; Ruby, Mahera; Jessel, John; Gregory, Eve; Arju, Tahera

    2007-01-01

    This study investigates the learning exchange between three- to six-year-old children and their grandparents, in Sylheti/Bengali-speaking families of Bangladeshi origin and monolingual English-speaking families living in east London. The following concepts from sociocultural theory are applied to this new area of intergenerational learning:…

  8. 'ah famous citie' : women, writing, and early modern London

    NARCIS (Netherlands)

    Wilcox - Boulton, Helen

    2010-01-01

    This article explores aspects of the textual relationship between women and early modern London by examining three verbal 'snapshots' of the city in works either written by women or focusing on women in their urban environment. The first text, Isabella Whitney's 'Wyll and Testament' (1573), addresse

  9. Middling migration: contradictory mobility experiences of Indian youth in London

    NARCIS (Netherlands)

    Rutten, M.; Verstappen, S.

    2012-01-01

    In this paper we examine the contradictory migration experiences of Indian youngsters who recently moved to Britain on a student or temporary work visa. All of them lived in London at the time of the interview, and are from middle class families in Gujarat. Like many of their peers in developing

  10. Participation and Performance at the London 2012 Olympics

    NARCIS (Netherlands)

    Kuper, Gerard H.; Sterken, Elmer

    2012-01-01

    The current paper predicts the medal tally for the London 2012 Olympic Games. The forecast procedure consists of analyzing participation and success at the country level of the three most recent editions of the Olympic Summer Games. Potential explanatory variables for medal winnings are income per c

  11. Entrepreneurship and UK Doctoral Graduates

    Science.gov (United States)

    Hooley, Tristram; Bentley, Kieran; Marriott, John

    2011-01-01

    This paper discusses the experience of UK doctoral graduates in pursuing entrepreneurial careers: there is evidence that this applies to a substantial number--about 10%--of doctoral graduates. The nature of their experience was explored using 37 interviews with doctoral entrepreneurs. The research was funded by Vitae (www.vitae.ac.uk), an…

  12. Call centres: constructing flexibility

    OpenAIRE

    Arzbächer, Sandra; Holtgrewe, Ursula; Kerst, Christian

    2002-01-01

    "The development of call centres as a flexible interface between firms and their environments has been seen as exemplary or even symptomatic of flexible capitalism (Sennett 1998). We are going to point out that they do not just stand for organisational change but also for changes of institutions towards deregulation. Employers and managers hoped for gains of flexibility, decreasing labour costs, and market gains by an expanded 24-hour-service. Surveillance and control by flexib...

  13. Impact on and use of an inner-city London Infectious Diseases Department by international migrants: a questionnaire survey

    Directory of Open Access Journals (Sweden)

    Holmes Alison

    2007-07-01

    Full Text Available Abstract Background The UK has witnessed a considerable increase in immigration in the past decade. Migrant may face barriers to accessing appropriate health care on arrival and the current focus on screening certain migrants for tuberculosis on arrival is considered inadequate. We assessed the implications for an inner-city London Infectious Diseases Department in a high migrant area. Methods We administered an anonymous 20-point questionnaire survey to all admitted patients during a 6 week period. Questions related to sociodemographic characteristics and clinical presentation. Analysis was by migration status (UK born vs overseas born. Results 111 of 133 patients completed the survey (response rate 83.4%. 58 (52.2% were born in the UK; 53 (47.7% of the cohort were overseas born. Overseas-born were over-represented in comparison to Census data for this survey site (47.7% vs 33.6%; proportional difference 0.142 [95% CI 0.049–0.235]; p = 0.002: overseas born reported 33 different countries of birth, most (73.6% of whom arrived in the UK pre-1975 and self-reported their nationality as British. A smaller number (26.4% were new migrants to the UK (≤10 years, mostly refugees/asylum seekers. Overseas-born patients presented with a broad range and more severe spectrum of infections, differing from the UK-born population, resulting in two deaths in this group only. Presentation with a primary infection was associated with refugee/asylum status (n = 8; OR 6.35 [95% CI 1.28–31.50]; p = 0.023, being a new migrant (12; 10.62 [2.24–50.23]; p = 0.003, and being overseas born (31; 3.69 [1.67–8.18]; p = 0.001. Not having registered with a primary-care physician was associated with being overseas born, being a refugee/asylum seeker, being a new migrant, not having English as a first language, and being in the UK for ≤5 years. No significant differences were found between groups in terms of duration of illness prior to presentation or duration of

  14. Historical centres: changing definitions

    Directory of Open Access Journals (Sweden)

    Roberta Lazzarotti

    2014-02-01

    Full Text Available Since the end of the Second World War, the architectural and planning culture has been showing a fluctuating attention to the theme of historical centres and their enhancement. First of all this uneven progress explains the difficulty to reach a homogeneous definition and this is still lacking. During a long phase of this period, the historical parts of the town were considered as objects to be preserved in an integral way, as urban monuments. This is mostly due to the high symbolic value of these settlements, that represent fundamental landmarks. Identity building and empowerment of local communities are indispensable conditions for any development programme, especially in the case of centres or other historic environments at risk of abandonment. The progressive evolution of this concept brings awareness of the impossibility of separating – either in analytical or in planning terms ­ historical centres from their urban and territorial contexts, which are linked by mutual, deep relationships. This article attempts to retrace the steps signaled by the publication of international documents and conventions, from the Charter of Gubbio (1960 to the Charter of Krakow and the European Landscape Convention (2000; they obviously represent particular points of view, not exhaustive of the richness of the positions in the debate, but extremely significant in terms of diffusion and consensus.

  15. Sébastien Lechevalier (editor), The Great Transformation of Japanese Capitalism. London: Routledge, 2014. 240 pp

    DEFF Research Database (Denmark)

    Kravtsova, Victoria

    2015-01-01

    Book review of: Sébastien Lechevalier (editor), The Great Transformation of Japanese Capitalism. London: Routledge, 2014.......Book review of: Sébastien Lechevalier (editor), The Great Transformation of Japanese Capitalism. London: Routledge, 2014....

  16. A Roof over your Head; House Price Peaks in the UK and Ireland

    CERN Document Server

    Richmond, P

    2006-01-01

    We analyse, following recent work of Roehner, changes in house prices for both the UK and Ireland. We conclude that prices in London have reached a tipping point and prices relative to inflation are set to fall over the next few years. If inflation does not rise then a hard landing seems likely. House prices in the Irish Republic are shown to have broken away from the moderate rise still to be found in Northern Ireland and Dublin has emerged as another global 'hot spot'. An evolution of Dublin house prices similar to that in London can be anticipated. Keywords: Econophysics, house prices, real estate, prediction PACS: 89.65.Gh, 89.90.+n

  17. Contrasting fortunes: lope in the uk/Shakespeare in Spain Contrasting fortunes: lope in the uk/Shakespeare in Spain

    Directory of Open Access Journals (Sweden)

    Keith Gregor

    2008-04-01

    Full Text Available In April 2004 the RSC began a season of five plays chosen from the vast, and still largely unexplored corpus of Spanish “Golden Age” drama. Laurence Boswell, who had received plaudits and also the Olivier Award for the SGA season he had conducted at The Gate theatre in London in 1992, was once again appointed to initiate audiences at Stratford, London and the provinces in the subtleties of the comedia form. And though at least two of the plays selected—Cervantes’s Pedro, the Great Pretender (directed by Mike Alfreds and the Mexican nun Sor Juana Inés de la Cruz’s House of Desires (directed by Nancy Meckler—had never been performed on the mainstream British stage, the pre-season hype and, naturally, Boswell himself were confident that the “plot-driven stories” of each of the plays, stories showing “essential human situations, like couples struggling with very recognizable dilemmas of love” (Boswell 2004, were what put them at the very centre of the European folk drama genre. In April 2004 the RSC began a season of five plays chosen from the vast, and still largely unexplored corpus of Spanish “Golden Age” drama. Laurence Boswell, who had received plaudits and also the Olivier Award for the SGA season he had conducted at The Gate theatre in London in 1992, was once again appointed to initiate audiences at Stratford, London and the provinces in the subtleties of the comedia form. And though at least two of the plays selected—Cervantes’s Pedro, the Great Pretender (directed by Mike Alfreds and the Mexican nun Sor Juana Inés de la Cruz’s House of Desires (directed by Nancy Meckler—had never been performed on the mainstream British stage, the pre-season hype and, naturally, Boswell himself were confident that the “plot-driven stories” of each of the plays, stories showing “essential human situations, like couples struggling with very recognizable dilemmas of love” (Boswell 2004, were what put them at the

  18. Tele-centres in Ghana

    DEFF Research Database (Denmark)

    Falch, Morten

    2004-01-01

    Tele-centres offer a low cost opportunity for the many who cannot afford their own phone or Internet connection. This paper presents a field study of tele-centres in Ghana and analyses how they contribute to universal access.......Tele-centres offer a low cost opportunity for the many who cannot afford their own phone or Internet connection. This paper presents a field study of tele-centres in Ghana and analyses how they contribute to universal access....

  19. UK Environmental Prediction - integration and evaluation at the convective scale

    Science.gov (United States)

    Fallmann, Joachim; Lewis, Huw; Castillo, Juan Manuel; Pearson, David; Harris, Chris; Saulter, Andy; Bricheno, Lucy; Blyth, Eleanor

    2016-04-01

    It has long been understood that accurate prediction and warning of the impacts of severe weather requires an integrated approach to forecasting. For example, high impact weather is typically manifested through various interactions and feedbacks between different components of the Earth System. Damaging high winds can lead to significant damage from the large waves and storm surge along coastlines. The impact of intense rainfall can be translated through saturated soils and land surface processes, high river flows and flooding inland. The substantial impacts on individuals, businesses and infrastructure of such events indicate a pressing need to understand better the value that might be delivered through more integrated environmental prediction. To address this need, the Met Office, NERC Centre for Ecology & Hydrology and NERC National Oceanography Centre have begun to develop the foundations of a coupled high resolution probabilistic forecast system for the UK at km-scale. This links together existing model components of the atmosphere, coastal ocean, land surface and hydrology. Our initial focus has been on a 2-year Prototype project to demonstrate the UK coupled prediction concept in research mode. This presentation will provide an update on UK environmental prediction activities. We will present the results from the initial implementation of an atmosphere-land-ocean coupled system and discuss progress and initial results from further development to integrate wave interactions. We will discuss future directions and opportunities for collaboration in environmental prediction, and the challenges to realise the potential of integrated regional coupled forecasting for improving predictions and applications.

  20. Development of a novel walkability index for London, United Kingdom: cross-sectional application to the Whitehall II Study.

    Science.gov (United States)

    Stockton, Jemima C; Duke-Williams, Oliver; Stamatakis, Emmanuel; Mindell, Jennifer S; Brunner, Eric J; Shelton, Nicola J

    2016-05-18

    Physical activity is essential for health; walking is the easiest way to incorporate activity into everyday life. Previous studies report positive associations between neighbourhood walkability and walking but most focused on cities in North America and Australasia. Urban form with respect to street connectivity, residential density and land use mix-common components of walkability indices-differs in European cities. The objective of this study was to develop a walkability index for London and test the index using walking data from the Whitehall II Study.  A neighbourhood walkability index for London was constructed, comprising factors associated with walking behaviours: residential dwelling density, street connectivity and land use mix. Three models were produced that differed in the land uses included. Neighbourhoods were operationalised at three levels of administrative geography: (i) 21,140 output areas, (ii) 633 wards and (iii) 33 local authorities. A neighbourhood walkability score was assigned to each London-dwelling Whitehall II Study participant (2003-04, N = 3020, mean ± SD age = 61.0 years ± 6.0) based on residential postcode. The effect of changing the model specification and the units of enumeration on spatial variation in walkability was examined. There was a radial decay in walkability from the centre to the periphery of London. There was high inter-model correlation in walkability scores for any given neighbourhood operationalisation (0.92-0.98), and moderate-high correlation between neighbourhood operationalisations for any given model (0.39-0.70). After adjustment for individual level factors and area deprivation, individuals in the most walkable neighbourhoods operationalised as wards were more likely to walk >6 h/week (OR = 1.4; 95 % CI: 1.1-1.9) than those in the least walkable. Walkability was associated with walking time in adults. This walkability index could help urban planners identify and design neighbourhoods in

  1. Thermonuclear fusion in the UK: towards a new abundant and durable energy source; La fusion nucleaire au Royaume-Uni: vers une nouvelle source d'energie abondante et durable

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-04-15

    The ITER treaty (International thermonuclear experimental reactor) was signed in Paris on November 21, 2006, by the European Union, China, the USA, Japan and Russia. This treaty is devoted to the construction and exploitation of the biggest thermonuclear facility ever, capable to generate 500 MW during a reaction of 10 minutes. ITER is a priori the last experimental step before the construction of a fusion power plant for power generation at the industrial scale. The goal of ITER is to obtain a quasi-unexhaustible and less polluting energy source by the mid-21. century. The British research work has largely contributed to the development of this technology through a large number of projects that have preceded ITER but also through its present day involvement in the creation of the future reactor of Cadarache. This document presents: the UK fusion program, the projects carried out at the Culham science centre (Compass-D, Joint European Torus (JET), Small Tight Aspect Ratio Tokamak (START), Mega-Ampere Spherical Tokamak (MAST), EASY-2005 (European activation system)), the British involvement in ITER project and the transfer of technologies, and the nuclear fusion research in British universities (PPRG Imperial College London, CFSA Warwick university, Dalton nuclear institute (DNI), department of physics York university). (J.S.)

  2. Thermonuclear fusion in the UK: towards a new abundant and durable energy source; La fusion nucleaire au Royaume-Uni: vers une nouvelle source d'energie abondante et durable

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-04-15

    The ITER treaty (International thermonuclear experimental reactor) was signed in Paris on November 21, 2006, by the European Union, China, the USA, Japan and Russia. This treaty is devoted to the construction and exploitation of the biggest thermonuclear facility ever, capable to generate 500 MW during a reaction of 10 minutes. ITER is a priori the last experimental step before the construction of a fusion power plant for power generation at the industrial scale. The goal of ITER is to obtain a quasi-unexhaustible and less polluting energy source by the mid-21. century. The British research work has largely contributed to the development of this technology through a large number of projects that have preceded ITER but also through its present day involvement in the creation of the future reactor of Cadarache. This document presents: the UK fusion program, the projects carried out at the Culham science centre (Compass-D, Joint European Torus (JET), Small Tight Aspect Ratio Tokamak (START), Mega-Ampere Spherical Tokamak (MAST), EASY-2005 (European activation system)), the British involvement in ITER project and the transfer of technologies, and the nuclear fusion research in British universities (PPRG Imperial College London, CFSA Warwick university, Dalton nuclear institute (DNI), department of physics York university). (J.S.)

  3. WISB: Warwick Integrative Synthetic Biology Centre.

    Science.gov (United States)

    McCarthy, John

    2016-06-15

    Synthetic biology promises to create high-impact solutions to challenges in the areas of biotechnology, human/animal health, the environment, energy, materials and food security. Equally, synthetic biologists create tools and strategies that have the potential to help us answer important fundamental questions in biology. Warwick Integrative Synthetic Biology (WISB) pursues both of these mutually complementary 'build to apply' and 'build to understand' approaches. This is reflected in our research structure, in which a core theme on predictive biosystems engineering develops underpinning understanding as well as next-generation experimental/theoretical tools, and these are then incorporated into three applied themes in which we engineer biosynthetic pathways, microbial communities and microbial effector systems in plants. WISB takes a comprehensive approach to training, education and outreach. For example, WISB is a partner in the EPSRC/BBSRC-funded U.K. Doctoral Training Centre in synthetic biology, we have developed a new undergraduate module in the subject, and we have established five WISB Research Career Development Fellowships to support young group leaders. Research in Ethical, Legal and Societal Aspects (ELSA) of synthetic biology is embedded in our centre activities. WISB has been highly proactive in building an international research and training network that includes partners in Barcelona, Boston, Copenhagen, Madrid, Marburg, São Paulo, Tartu and Valencia.

  4. Anthropological demography in Europe: Methodological lessons from a comparative ethnographic study in Athens and London

    Directory of Open Access Journals (Sweden)

    Katerina Georgiadis

    2007-07-01

    Full Text Available This paper offers a descriptive account of the methods used to conduct a comparative ethnographic study of below-replacement fertility in Athens, Greece and London, UK. It argues that in order for anthropology and demography to forge a closer relationship each discipline first needs to gain a deeper appreciation of the other's methodological perspectives. The following discussion presents the key anthropological approaches employed to realize a research project on low fertility in Europe, and provides justification for their use. While the practices described in this paper might be familiar to anthropologists and qualitative demographers, they are less well-known in the wider demographic community. Those convinced of the benefits of the ethnographic approach to the study of fertility are also invited to consider the specific obstacles encountered in the course of this enquiry. This paper reaches the following methodological conclusions: 1 Findings from two ethnographic studies of low fertility can be compared and generalised if such concepts as 'comparison' and 'generalisation' are understood in the anthropological sense. 2 Those investigating fertility in Europe must remain critical of their position relative to their study participants, even if they are undertaking research 'at home'. 3 Exploring attitudes towards reproduction and experiences of family-formation in an urban setting presents unique challenges as does 4 asking women about their childbearing beliefs and practices. 5 Analysing press perspectives on low fertility must involve treating media representations as 'discourse' and 6 qualitative studies are invaluable to the low fertility debate because of their thematic contributions.

  5. Seven years of teenage pregnancy in an inner London genitourinary medicine service - a retrospective cohort study.

    Science.gov (United States)

    Hegazi, Aseel; Daley, Natalie; Williams, Elizabeth; McLeod, Felicity; Rafiezadeh, Saba; Prime, Katia

    2014-12-01

    Young people attending genitourinary medicine services are at high risk of unplanned pregnancy. We performed a retrospective cohort study to identify characteristics of pregnant teenagers accessing an inner London genitourinary medicine service. There were 481 pregnancies in 458 teenagers with 54 previous pregnancies and 46 previous terminations of pregnancy. The under-18 and under-16 teenage pregnancy rates were 92.1 and 85.8 per 1000 age-matched clinic attendees, respectively. Median age was 17.1 years. 'Black Other' teenagers ('Black British', 'Mixed White-Black Caribbean' and 'Mixed White-Black African') were over-represented, compared to our clinic population, while those of White ethnicity were under-represented. Few pregnancies (1.5%) were planned with the majority (64%) intending terminations of pregnancy. Most teenagers did not use consistent contraception. Two-thirds of patients had attended genitourinary medicine services in the past and sexually transmitted infection prevalence at presentation was high. Effectively targeting the sexual and reproductive health needs of teenage genitourinary medicine clinic attendees may have a significant impact on reducing sexually transmitted infections, unplanned pregnancy and terminations of pregnancy in this group. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  6. ICU fire evacuation preparedness in London: a cross-sectional study.

    Science.gov (United States)

    Murphy, G R F; Foot, C

    2011-05-01

    Hospital fires present a sporadic but significant threat to patients and staff. This is especially so within an intensive care unit (ICU) setting, due to the complexity of moving acutely unwell patients reliant on invasive monitoring and organ support. Despite an average of 500 in-hospital fires reported to the UK department of health per annum, causing 65 injuries and 1-2 fatalities, the readiness of ICUs for urgent evacuation has not been assessed. A cross-sectional survey of all 50 adult and paediatric ICUs within the London Postgraduate Deanery was conducted; neonatal units were excluded. The senior nurse at each unit was asked to complete a 90-question structured questionnaire, covering unit patient characteristics, design, equipment, training, and their evacuation plan. Thirty-five of 50 (70%) responded within 2 months of the study. Significant weaknesses were reported in unit design, equipment, and planning. Unit design was compromised by inadequate fire doors (20%), ventilation cut-outs (17%), and escape routes (up to 60%). The ability to evacuate multiple patients simultaneously may be limited by a lack of portable monitoring equipment (49% of beds) and emergency drug supplies (20% of beds). Evacuation plans were often limited in their scope (96% expected to remain on their floor; 14% had plans to obtain medications after evacuation), and not rehearsed (60%). Staff training, while well provided for permanent staff, is less so for temporary staff (34%). Forward planning for an urgent evacuation can be improved.

  7. Key Barriers to Community Cohesion: Views from Residents of 20 London Deprived Neighbourhoods

    Science.gov (United States)

    Bertotti, Marcello; Adams-Eaton, Faye; Sheridan, Kevin; Renton, Adrian

    2016-01-01

    The notion of community has been central to the political project of renewal of New Labour in the UK. The paper explores how the discourses of community are framed within New Labour and discusses these in the light of the results from research which focuses on how people within urban deprived areas construct their community. It draws upon the results of one part of a larger research project (the ‘Well London’ programme) which aimed to capture the views of residents from 20 disadvantaged neighbourhoods throughout London using an innovative qualitative method known as the ‘World Café’. Our results show the centrality of young people to the development of cohesive communities, the importance of building informal relationships between residents alongside encouraging greater participation to policy making, and the need to see these places as fragile and temporary locations but with considerable social strengths. Government policies are only partially addressing these issues. They pay greater attention to formally encouraging citizens to become more involved in policy making, largely ignore the contribution young people could make to the community cohesion agenda, and weakly define the shared norms and values that are crucial in building cohesive communities. Thus, the conclusion is that whilst an emphasis of the government on ‘community’ is to be welcome, more needs to be done in terms of considering the ‘voices’ of the community as well as enabling communities to determine and act upon their priorities.

  8. Integrating research & teaching: the Queen Mary, University of London module in Geodiversity & Geoconservation

    Science.gov (United States)

    Gray, M.

    2012-04-01

    The School of Geography at Queen Mary, University of London has been running a Level 6 (undergraduate) module in "Geodiversity & Geoconservation" since 2004. The course is based around the book Geodiversity: valuing and conserving abiotic nature (John Wiley, 2004) but lectures are used to update each topic based on the latest research. The course is divided into 5 parts: 1. Defining and describing geodiversity - which discusses the concept of geodiversity, its definition and the nature of the geodiversity of Planet Earth; 2. Values of, and threats to, geodiversity - a lecture on valuing geodiversity is now based around important research on the role of geodiversity in "ecosystem services" assessments. A second lecture covers the major threats to geodiversity; 3. The protected area approach - lectures here cover geological World Heritage Sites, Global Geoparks, GSSPs, and national geoconservation systems in the UK, USA and other parts of the world; 4. Protecting geodiversity in the wider landscape - the contribution of geology and geomorphology to landscape character are described, together with the role of land-use planning and policy-making in protecting geodiversity. 5. Putting it all together - lectures here emphasize that geodiversity is an important basis for geoconservation, that different geoconservation methods are appropriate to different elements of geodiversity, and that integrated geo/bio conservation is essential. A field trip to three Chalk/Quaternary Sites of Special Scientific Interest in East Sussex is included which discusses some of the planning issues that have arisen at these sites, a theme that is expanded in the lectures.

  9. Communicating geohazard information for emergency responders, a case study from the UK.

    Science.gov (United States)

    Banks, Vanessa; Cooper, Anthony

    2016-04-01

    SSS11.4/ESSI4.6/HS11.39/NH9.13 Communication of uncertain information in earth sciences: data, models and visualization Communicating geohazard information for emergency responders, a case study from the UK. Cooper, A. H.1, Banks, V.J.1, Cowup, P.2, Curness, J.3, Davis, R.4, Dawson, L3. and Gazzard, L.4 1 British Geological Survey, Keyworth, NG12 5GG, UK 2 London Fire Brigade, 169 Union Street, London, SE1 0LL, UK 3.Coventry University, Priory Street, Coventry, CV1 5FB, UK 4.Avon Fire and Rescue, Temple Back, Bristol, BS1 6EU, UK. In February 2013 a sinkhole opened beneath a Florida Home resulting in the loss of a life and demolition of the affected home. The resulting void was in the order of 15 m deep. Neighbouring homes also had to be demolished. Television footage of this unfortunate incident resonated with an Assistant Commissioner of the London Fire Brigade who questioned whether or not such a feature would be recognised in the UK and if so, how the emergency response would be managed. Stemming from this, the British Geological Survey was invited to work with the Chief Fire Officers Association Urban Search and Rescue working group on geohazards. The aim of this group was to develop national tactical operational guidance on geohazards that would form the basis for regional guidance and training. The project was addressed collaboratively providing opportunities for two students from the Coventry University Disaster Management course, that were on placements with Avon Fire and Rescue, to work with the BGS to develop the guidance. Key to the success of the project was an iterative approach to knowledge exchange with respect to firstly, the characterization of the geohazards, and the processes and uncertainties associated with them and secondly, with respect to emergency responders' needs and priorities. Effective communication was achieved through challenging and rationalising the geoscience language for the end user and through a series of customised

  10. Town Centre Redevelopment Strategies

    DEFF Research Database (Denmark)

    Vagnby, Bo Hellisen

    After many years of urban growth Danish downtowns are facing some important choices. Shall the stake one-sidedly be on the town centres as driving forces for growth and 'city marketing', or do they still have a role to play in a broader socio-economic context? In the paper we look back on eight...... as slum clearence and urban renewal. To a certain extent parallels are drawn to international experiences, especially where these are of such a nature that they can be assumed transferred to Danish connctions. Conclusively, the strategies are discussed in the light of the turn of Danish urban planning...

  11. UK parents' attitudes towards meningococcal group B (MenB) vaccination: a qualitative analysis.

    Science.gov (United States)

    Jackson, Cath; Yarwood, Joanne; Saliba, Vanessa; Bedford, Helen

    2017-05-04

    (1) To explore existing knowledge of, and attitudes, to group B meningococcal disease and serogroup B meningococcal (MenB) vaccine among parents of young children. (2) To seek views on their information needs. Cross-sectional qualitative study using individual and group interviews conducted in February and March 2015, prior to the introduction of MenB vaccine (Bexsero) into the UK childhood immunisation schedule. Community centres, mother and toddler groups, parents' homes and workplaces in London and Yorkshire. 60 parents of children under 2 years of age recruited via mother and baby groups and via an advert posted to a midwife-led Facebook group. Although recognising the severity of meningitis and septicaemia, parents' knowledge of group B meningococcal disease and MenB vaccine was poor. While nervous about fever, most said they would take their child for MenB vaccination despite its link to fever. Most parents had liquid paracetamol at home. Many were willing to administer it after MenB vaccination as a preventive measure, although some had concerns. There were mixed views on the acceptability of four vaccinations at the 12-month booster visit; some preferred one visit, while others favoured spreading the vaccines over two visits. Parents were clear on the information they required before attending the immunisation appointment. The successful implementation of the MenB vaccination programme depends on its acceptance by parents. In view of parents' recognition of the severity of meningitis and septicaemia, and successful introduction of other vaccines to prevent bacterial meningitis and septicaemia, the MenB vaccination programme is likely to be successful. However, the need for additional injections, the likelihood of post-immunisation fever and its management are issues about which parents will need information and reassurance from healthcare professionals. Public Health England has developed written information for parents, informed by these findings.

  12. Contact sensitivity to preservatives in the UK, 2004-2005: results of multicentre study.

    Science.gov (United States)

    Jong, Cherng T; Statham, Barry N; Green, Cathy M; King, Codagh M; Gawkrodger, David J; Sansom, Jane E; English, John S C; Wilkinson, S Mark; Ormerod, Anthony D; Chowdhury, Mahbub M U

    2007-09-01

    Preservative sensitivity in the UK was last assessed in 2000. Given the changes in preservative usage, we have re-evaluated our patch test data in order to detect any changes in the trend of sensitization. The results of patch testing using the extended British Contact Dermatitis Society Standard series were collected from 9 dermatology centres in the UK. Positive reactions to each of 10 preservative allergens were captured together with the MOAHFLA indices for each centre. In total, 6958 patients were tested during the period 2004-2005. The current data were compared with previously published data. Formaldehyde and methylchloroisothiazolinone/methyl-isothiazolinone have the highest positivity rates at 2.0% and chloroxylenol the lowest at 0.2%. Parabens mix has the highest irritancy rate. Compared with the UK data in 2000, the positivity rate of imidazolidinyl urea (0.02 methyldibromo glutaronitrile has significantly reduced (P < 0.001).

  13. A UK national audit of hereditary and acquired angioedema.

    Science.gov (United States)

    Jolles, S; Williams, P; Carne, E; Mian, H; Huissoon, A; Wong, G; Hackett, S; Lortan, J; Platts, V; Longhurst, H; Grigoriadou, S; Dempster, J; Deacock, S; Khan, S; Darroch, J; Simon, C; Thomas, M; Pavaladurai, V; Alachkar, H; Herwadkar, A; Abinun, M; Arkwright, P; Tarzi, M; Helbert, M; Bangs, C; Pastacaldi, C; Phillips, C; Bennett, H; El-Shanawany, T

    2014-01-01

    Hereditary angioedema (HAE) and acquired angioedema (AAE) are rare life-threatening conditions caused by deficiency of C1 inhibitor (C1INH). Both are characterized by recurrent unpredictable episodes of mucosal swelling involving three main areas: the skin, gastrointestinal tract and larynx. Swelling in the gastrointestinal tract results in abdominal pain and vomiting, while swelling in the larynx may be fatal. There are limited UK data on these patients to help improve practice and understand more clearly the burden of disease. An audit tool was designed, informed by the published UK consensus document and clinical practice, and sent to clinicians involved in the care of HAE patients through a number of national organizations. Data sets on 376 patients were received from 14 centres in England, Scotland and Wales. There were 55 deaths from HAE in 33 families, emphasizing the potentially lethal nature of this disease. These data also show that there is a significant diagnostic delay of on average 10 years for type I HAE, 18 years for type II HAE and 5 years for AAE. For HAE the average annual frequency of swellings per patient affecting the periphery was eight, abdomen 5 and airway 0·5, with wide individual variation. The impact on quality of life was rated as moderate or severe by 37% of adult patients. The audit has helped to define the burden of disease in the UK and has aided planning new treatments for UK patients.

  14. The sexual attitudes and lifestyles of London's Eastern Europeans (SALLEE Project: design and methods

    Directory of Open Access Journals (Sweden)

    French Rebecca S

    2009-10-01

    Full Text Available Abstract Background Since May 2004, ten Central and Eastern European (CEE countries have joined the European Union, leading to a large influx of CEE migrants to the United Kingdom (UK. The SALLEE project (sexual attitudes and lifestyles of London's Eastern Europeans set out to establish an understanding of the sexual lifestyles and reproductive health risks of CEE migrants. CEE nationals make up a small minority of the population resident in the UK with no sampling frame from which to select a probability sample. There is also difficulty estimating the socio-demographic and geographical distribution of the population. In addition, measuring self-reported sexual behaviour which is generally found to be problematic, may be compounded among people from a range of different cultural and linguistic backgrounds. This paper will describe the methods adopted by the SALLEE project to address these challenges. Methods The research was undertaken using quantitative and qualitative methods: a cross-sectional survey of CEE migrants based on three convenience samples (recruited from community venues, sexual health clinics and from the Internet and semi-structured in-depth interviews with a purposively selected sample of CEE migrants. A detailed social mapping exercise of the CEE community was conducted prior to commencement of the survey to identify places where CEE migrants could be recruited. A total of 3,005 respondents took part in the cross-sectional survey, including 2,276 respondents in the community sample, 357 in the clinic sample and 372 in the Internet sample. 40 in-depth qualitative interviews were undertaken with a range of individuals, as determined by the interview quota matrix. Discussion The SALLEE project has benefited from using quantitative research to provide generalisable data on a range of variables and qualitative research to add in-depth understanding and interpretation. The social mapping exercise successfully located a large number

  15. Rock and mineral physics at University College London

    Science.gov (United States)

    Dennis, Paul; Meredith, Philip; Price, David

    The Department of Geological Sciences at University College London (UCL), has undergone a period of major expansion and growth as a result of the restructuring of geology departments within the University of London that was carried out in 1982. This exercise produced the amalgamation of selected parts of the Department of Geological Sciences of Queen Mary College and the Department of Geology, UCL, on the UCL site. The creation of this strengthened grouping has been successful in attracting a significant number of active researchers in the field of rock and mineral physics (RMP) to the new UCL department. As a result, the academic staff has more than douhled since 1982 and now stands at 31.

  16. A mathematical model of the London riots and their policing.

    Science.gov (United States)

    Davies, Toby P; Fry, Hannah M; Wilson, Alan G; Bishop, Steven R

    2013-01-01

    In August 2011, several areas of London experienced episodes of large-scale disorder, comprising looting, rioting and violence. Much subsequent discourse has questioned the adequacy of the police response, in terms of the resources available and strategies used. In this article, we present a mathematical model of the spatial development of the disorder, which can be used to examine the effect of varying policing arrangements. The model is capable of simulating the general emergent patterns of the events and focusses on three fundamental aspects: the apparently-contagious nature of participation; the distances travelled to riot locations; and the deterrent effect of policing. We demonstrate that the spatial configuration of London places some areas at naturally higher risk than others, highlighting the importance of spatial considerations when planning for such events. We also investigate the consequences of varying police numbers and reaction time, which has the potential to guide policy in this area.

  17. Intussusception and the great smog of London, December 1952.

    Science.gov (United States)

    Black, J

    2003-12-01

    To discuss the possible significance of the increased incidence of intussusception in children in relation to the "Great Smog" of London in December 1952. Cases of intussusception were recorded in two hospitals in East London for the years 1951, 1952, 1953, and 1954. For 1952 the actual dates of admission were recorded. During the year 1952 the total number of cases of intussusception greatly exceeded that in the previous and succeeding years. Immediately during and after the fog there was a clustering of cases, which only occurred during this period. The increased incidence of cases during 1952 is thought to reflect the annual variation in incidence resulting from changes in the prevalence of viruses capable of causing intussusception. The clustering of cases in relation to the fog may reflect a facilitated entry of virus through the wall of the terminal ileum due to the effect of swallowed irritants such as sulphurous acid and smoke particles.

  18. "Mothering through Islam": Narratives of Religious Identity in London

    Directory of Open Access Journals (Sweden)

    Louise Ryan

    2013-04-01

    Full Text Available This paper draws upon research with mothers of diverse Muslim backgroundsin London to explore how these women use ‘conservative’ interpretations ofIslamic beliefs and practices to underpin their parenting strategies. In particularthe paper looks at how mothers use religion as a frame to make sense of andgive meaning to their experiences and encounters in Britain. We suggest thatthe women use Islam in four key ways: (i as a framework for teaching theirchildren right and wrong, (ii as a means of protecting children from the ‘moral’dangers of British society, (iii as an authoritative voice that reinforces parentingand (iv as a means of critiquing specific aspects of both the traditional andBritish culture in which they live and daily negotiate their different cultural andreligious belonging. In attempting to instil religious values in their London-basedchildren, these mothers have to negotiate the hostility that Islam increasinglyprovokes in British society’s public arenas.

  19. Chinese herbal medicine for treating menopausal symptoms in London women: developing a good practice protocol via the factor analysis of prescribing patterns in a clinical study.

    Science.gov (United States)

    Scheid, Volker; Tuffrey, Veronica; Bovey, Mark

    2017-06-01

    The objective of the study described in this paper was to define Chinese medicine formula patterns for the treatment of menopausal women in London. These formula patterns are intended to inform the development of best practice guidelines for a future pragmatic randomised controlled trial, with the ultimate goal of evaluating the possibility of integrating Chinese medicine treatment strategies for menopausal symptoms into the UK National Health Service. Data from a clinical study that had demonstrated the effectiveness and safety of Chinese medicine in treating 117 perimenopausal women at the Westminster University Polyclinic in London were analysed for symptom occurrence and herb use. The frequency of occurrence of different presenting symptoms and the frequency of use of individual herbs is described, the patterns of combined herb use were analysed by means of factor analysis, and the correlations between these patterns and the presenting symptoms were analysed using the chi square test. Treating the emergent use patterns as Chinese herbal medicine formulas, five distinctive formula patterns emerged in the course of this study. While there is some overlap between these formulas and their associated symptom patterns and those described in Chinese medicine textbooks and guidelines, some formula patterns appear to be unique to London women. This indicates that best practice guidelines for the Chinese medicine treatment of menopausal symptoms, which have been shown to vary cross-culturally, need to be derived from local clinical practice. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. UK businesses bag innovation awards

    Science.gov (United States)

    Banks, Michael

    2015-09-01

    Five UK firms have received innovation awards from the Institute of Physics (IOP), which publishes Physics World. Hallmarq Veterinary Imaging, Metrasens, M Squared Lasers, Silixa and Tracerco have all won an IOP award for developing new innovative products.

  1. UK science, post-Brexit

    National Research Council Canada - National Science Library

    James Wilsdon

    2017-01-01

    Nine months since the British vote to exit the European Union ("Brexit"), the UK science community's initial dismay has given way to hard-boiled determination to limit the damage it will do to universities and research...

  2. UK Punched Card Reference Manuals

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Documentation for using and reading punched cards kept at the UK Met Office. Includes five Marine and one upper air manual, dated from 1953-1981.

  3. "UK today" Tallinnas / Tuuli Oder

    Index Scriptorium Estoniae

    Oder, Tuuli, 1958-

    2001-01-01

    Vabariikliku inglise keele olümpiaadi raames toimus Tallinnas viktoriini "UK today" lõppvoor. Osalesid 22 kooli kaheliikmelised võistkonnad. Viktoriini tulemused koolide lõikes ja küsimused õigete vastustega

  4. Intergenerational learning between children and grandparents in East London

    OpenAIRE

    Kenner, Charmian; Gregory, Eve E.; Jessel, John; Ruby, Mahera; Arju, Tahera

    2004-01-01

    The study set out to investigate learning events taking place between young children and grandparents in London's East End, both in activities where older people have traditionally provided support (such as storytelling) and in the newer areas of information and communication technology where children have competences which their grandparents would like to access. This area of family learning is growing in significance as grandparents are increasingly taking on a childcare role in different e...

  5. Has UK energy policy failed

    Energy Technology Data Exchange (ETDEWEB)

    Parker, M.J. (Sussex University, Brighton (United Kingdom). Science Policy Research Unit)

    1993-01-01

    The coal crisis of last October focused attention on the UK's energy supplies and led many to criticise the government's energy policy. Are these criticisms justified Was the crisis a massive policy failure An Honorary Fellow at the Science Policy Research Unit at Sussex University and formerly Director of Economics at British Coal, assesses UK energy policy and highlights some of the outstanding issues. 1 tab.

  6. Unified storage systems for distributed Tier-2 centres

    CERN Document Server

    Cowan, Greig A; Elwell, Andrew

    2008-01-01

    The start of data taking at the Large Hadron Collider will herald a new era in data volumes and distributed processing in particle physics. Data volumes of hundreds of Terabytes will be shipped to Tier-2 centres for analysis by the LHC experiments using the Worldwide LHC Computing Grid (WLCG). In many countries Tier-2 centres are distributed between a number of institutes, e.g., the geographically spread Tier-2s of GridPP in the UK. This presents a number of challenges for experiments to utilise these centres efficaciously, as CPU and storage resources may be sub-divided and exposed in smaller units than the experiment would ideally want to work with. In addition, unhelpful mismatches between storage and CPU at the individual centres may be seen, which make efficient exploitation of a Tier-2's resources difficult. One method of addressing this is to unify the storage across a distributed Tier-2, presenting the centres' aggregated storage as a single system. This greatly simplifies data management for the VO, ...

  7. Enhancing Resilience of London by Learning from Experiences

    Directory of Open Access Journals (Sweden)

    Funda Atun

    2012-07-01

    Full Text Available The concept of resilience was introduced at the beginning of the 70s to indicate the capability of natural systems to absorb perturbations, preserving their structure and keeping the system functioning. The paper considers London as an example to a resilient city by focusing on some remarkable disasters in the history of London, such as the Great Fire of 1666, the air raids during the World War 2, 18 December 1987 Kings Cross Fire, terrorist attack to tube network on the 7th of July 2005, 1928 flooding and 1953 storm surge. The paper starts by giving short descriptions of these disasters and continues by discussing the lessons learned. In this paper, the concept of resilience has been studied in three phases: prepare for, respond to and recover from a disaster. Besides, actions that have to be taken according to these three phases are going to be explored in detail. In conclusion, the notable effects of the mentioned disasters on the structural and non-structural tools for disaster prevention have been revealed by considering resilience of London.

  8. Evolving Pb isotope signatures of London airborne particulate matter (PM 10)-constraints from on-filter and solution-mode MC-ICP-MS.

    Science.gov (United States)

    Noble, Stephen R; Horstwood, Matthew S A; Davy, Pamela; Pashley, Vanessa; Spiro, Baruch; Smith, Steve

    2008-07-01

    Pb isotope compositions of biologically significant PM(10) atmospheric particulates from a busy roadside location in London UK were measured using solution- and laser ablation-mode MC-ICP-MS. The solution-mode data for PM(10) sampled between 1998-2001 document a dramatic shift to increasingly radiogenic compositions as leaded petrol was phased out. LA-MC-ICP-MS isotope analysis, piloted on a subset of the available samples, is shown to be a potential reconnaissance analytical technique. PM(10) particles trapped on quartz filters were liberated from the filter surface, without ablating the filter substrate, using a 266 nm UV laser and a dynamic, large diameter, low-fluence ablation protocol. The Pb isotope evolution noted in the London data set obtained by both analytical protocols is similar to that observed elsewhere in Western Europe following leaded petrol elimination. The data therefore provide important baseline isotope composition information useful for continued UK atmospheric monitoring through the early 21(st) century.

  9. London 2012: espacio de excepción London 2012: espaço de exceção;London 2012: space of exception

    Directory of Open Access Journals (Sweden)

    Isaac Marrero-Guillamón

    2011-12-01

    Full Text Available La teoría del estado de excepción de Giorgio Agamben, según la cual, lejos de ser una medida provisional y extraordinaria, éste habría devenido una técnica de gobierno, puede ayudar a entender la configuración legal y espacial de los Juegos Olímpicos. Este texto analiza los documentos fundamentales de la arquitectura legal de London 2012 con el fin de mostrar su impacto en la regulación y vigilancia del espacio económico y político de la ciudad. Tras presentar los pilares fundamentales de la gobernanza olímpica, el texto se centra en la configuración jurídica de la excepcionalidad. A través de un sistema de legitimación basado en la necesidad y la amenaza, la normativa asociada a los Juegos aprobada por el Gobierno Británico logra efectivamente materializar un estado de excepción: una suerte de paraíso capitalista, en el que la actividad económica está regulada por contratos exclusivos, toda actividad política está criminalizada, y los privilegios son protegidos policial y militarmente. De aquí que London 2012 pueda ser calificado como un “espacio de excepción”.

  10. UK Environmental Prediction - integration and evaluation at the convective scale

    Science.gov (United States)

    Fallmann, Joachim; Lewis, Huw; Castillo, Juan Manuel; Pearson, David; Harris, Chris; Saulter, Andy; Bricheno, Lucy; Blyth, Eleanor

    2016-04-01

    Traditionally, the simulation of regional ocean, wave and atmosphere components of the Earth System have been considered separately, with some information on other components provided by means of boundary or forcing conditions. More recently, the potential value of a more integrated approach, as required for global climate and Earth System prediction, for regional short-term applications has begun to gain increasing research effort. In the UK, this activity is motivated by an understanding that accurate prediction and warning of the impacts of severe weather requires an integrated approach to forecasting. The substantial impacts on individuals, businesses and infrastructure of such events indicate a pressing need to understand better the value that might be delivered through more integrated environmental prediction. To address this need, the Met Office, NERC Centre for Ecology & Hydrology and NERC National Oceanography Centre have begun to develop the foundations of a coupled high resolution probabilistic forecast system for the UK at km-scale. This links together existing model components of the atmosphere, coastal ocean, land surface and hydrology. Our initial focus has been on a 2-year Prototype project to demonstrate the UK coupled prediction concept in research mode. This presentation will provide an update on UK environmental prediction activities. We will present the results from the initial implementation of an atmosphere-land-ocean coupled system, including a new eddy-permitting resolution ocean component, and discuss progress and initial results from further development to integrate wave interactions in this relatively high resolution system. We will discuss future directions and opportunities for collaboration in environmental prediction, and the challenges to realise the potential of integrated regional coupled forecasting for improving predictions and applications.

  11. Stavanger Squash Centre, Norway

    Energy Technology Data Exchange (ETDEWEB)

    Rostvik, H. [Sunlab/ABB, Stavanger (Norway)

    1999-07-01

    Although Stavanger is the technological and financial oil-capital of Norway, the Stavanger Squash Centre was until recently the largest solar building in Norway, with 120 m{sup 2} of collectors. The active, building-integrated, solar air collector in the 45 {sup o} roof facing 15 {sup o} east of due south, has now been delivering solar-heated hot water for the showers for 15 years. The solar system consists of several standard products put together in a new way. Monitoring has shown that the system produced 18,000 kWh/m{sup 2} a (150 kWh/m{sub coll} {sup 2}a). If operated as planned, it could have had a solar contribution of 45,000 kWh/a) (375 kWh/m{sub coll} {sup 2}a), resulting in a 19% solar fraction of total demand. (author)

  12. A cancer help centre.

    Science.gov (United States)

    Daniel, R

    1996-06-01

    The diagnosis of cancer can be shattering to all involved. The treatment of cancer is intense and often very challenging. Prevailing attitudes to cancer are sometimes fearful, negative and depressing. This combination may leave those affected by cancer shocked, disorientated and without hope. Even worse than this, on asking consultants 'What can I do to help myself?' patients are frequently told 'Absolutely nothing'--crushing in one fell swoop their remaining fighting spirit. Not so in the case of Penny Brohn, who, when faced with the diagnosis of breast cancer, travelled the world to find alternative cancer treatments, and having successfully brought her own cancer under control, dedicated her life to creating a Centre for others wishing to fight their disease.

  13. Discrimination and common mental disorder among migrant and ethnic groups: findings from a South East London Community sample.

    Science.gov (United States)

    Hatch, S L; Gazard, B; Williams, D R; Frissa, S; Goodwin, L; Hotopf, M

    2016-05-01

    Few studies have examined discrimination and mental health in the UK, particularly by migrant status and in urban contexts with greater demographic diversity. This study aims to (1) describe the prevalence of discrimination experiences across multiple life domains; (2) to describe associations between discrimination experiences and common mental disorder (CMD); (3) to determine whether or not the relationship between discrimination and CMD varies by migrant status and ethnicity. Data on major, anticipated and everyday discrimination and CMD symptoms were collected from an ethnically diverse prospective sample of 1052 participants followed up from 2008 to 2013 in the South East London Community Health study, a population-based household survey. With few exceptions, discrimination was most prevalent among those in the Black Caribbean group. However, those in the White Other ethnic group had similar or greater reporting major and anticipated discrimination to Black or mixed ethnic minority groups. The effects of discrimination on CMD were most pronounced for individuals who had recently migrated to the UK, an ethnically heterogeneous group, and for Black and Mixed ethnic minority groups in partially adjusted models. Prior CMD accounted for differences between the Mixed and White British ethnic groups, but the strength of the association for the most recent migrant group and the Black ethnic groups remained two or more times greater than the reference groups. The strength of the relationship suggests a need for more consideration of migration status along with ethnicity in examining the impact of discrimination on mental disorder in community and clinical samples.

  14. E-Tendering Process Within Construction: A UK Perspective

    Institute of Scientific and Technical Information of China (English)

    Geoff Tindsley; Paul Stephenson

    2008-01-01

    E-tendering can be defined as the issue and receipt of tender documentation through electronic means which facilitates the procurement of construction work and the award of contracts. The current paper-based method of tendering has been commonplace within the industry for a significant number of years, but with recent technological advancements, this traditional process is rapidly becoming outdated. Several ma-jor projects within the UK are now being procured through the e-tendering process which includes the multi-billion pound development for the Olympic Games in London 2012. However, while these prestigious pro-jects are embracing e-tendering technology, it is not certain as to what extent e-tendering is used across the construction sector generally. This research is primarily concemed with establishing the current status, prac-ticalities and resource effectiveness of e-tendering within UK construction. Results are provided from an in-dustry survey which includes both quantitative and qualitative data. A case study implementation is also in-cluded which assesses the utilisation of e-tendering software in practice. The research findings indicated that e-tendering can provide substantial resource savings to a major part of the supply chain, with the key benefits being enhanced communication, time savings and reduced costs. However, a considerable propor-tion of the industry remains uncertain about embracing new technologies, with reluctance to change being perceived as the greatest barrier. The findings suggest that many professionals within the UK construction industry recognise a requirement for increased implementation of e-tendering, but feel that training, educa-tion and support from senior management are essential requirements for e-tendering to become widely ac-cepted in the future.

  15. Call Centre- Computer Telephone Integration

    Directory of Open Access Journals (Sweden)

    Dražen Kovačević

    2012-10-01

    Full Text Available Call centre largely came into being as a result of consumerneeds converging with enabling technology- and by the companiesrecognising the revenue opportunities generated by meetingthose needs thereby increasing customer satisfaction. Regardlessof the specific application or activity of a Call centre, customersatisfaction with the interaction is critical to the revenuegenerated or protected by the Call centre. Physical(v, Call centreset up is a place that includes computer, telephone and supervisorstation. Call centre can be available 24 hours a day - whenthe customer wants to make a purchase, needs information, orsimply wishes to register a complaint.

  16. Atmospheric ethanol in London and the potential impacts of future fuel formulations.

    Science.gov (United States)

    Dunmore, Rachel E; Whalley, Lisa K; Sherwen, Tomás; Evans, Mathew J; Heard, Dwayne E; Hopkins, James R; Lee, James D; Lewis, Alastair C; Lidster, Richard T; Rickard, Andrew R; Hamilton, Jacqueline F

    2016-07-18

    There is growing global consumption of non-fossil fuels such as ethanol made from renewable biomass. Previous studies have shown that one of the main air quality disadvantages of using ethanol blended fuels is a significant increase in the production of acetaldehyde, an unregulated and toxic pollutant. Most studies on the impacts of ethanol blended gasoline have been carried out in the US and Brazil, with much less focus on the UK and Europe. We report time resolved measurements of ethanol in London during the winter and summer of 2012. In both seasons the mean mixing ratio of ethanol was around 5 ppb, with maximum values over 30 ppb, making ethanol currently the most abundant VOC in London air. We identify a road transport related source, with 'rush-hour' peaks observed. Ethanol is strongly correlated with other road transport-related emissions, such as small aromatics and light alkanes, and has no relationship to summer biogenic emissions. To determine the impact of road transport-related ethanol emission on secondary species (i.e. acetaldehyde and ozone), we use both a chemically detailed box model (incorporating the Master Chemical Mechanism, MCM) and a global and nested regional scale chemical transport model (GEOS-Chem), on various processing time scales. Using the MCM model, only 16% of the modelled acetaldehyde was formed from ethanol oxidation. However, the model significantly underpredicts the total levels of acetaldehyde, indicating a missing primary emission source, that appears to be traffic-related. Further support for a primary emission source comes from the regional scale model simulations, where the observed concentrations of ethanol and acetaldehyde can only be reconciled with the inclusion of large primary emissions. Although only constrained by one set of observations, the regional modelling suggests a European ethanol source similar in magnitude to that of ethane (∼60 Gg per year) and greater than that of acetaldehyde (∼10 Gg per year). The

  17. Recruitment to UK cardiothoracic surgery in the era of public outcome reporting.

    Science.gov (United States)

    Westaby, Stephen; Baig, Kamran; De Silva, Ravi; Unsworth-White, Jonathan; Pepper, John

    2015-04-01

    Since 1999 important widely publicized issues have affected morale in UK cardiothoracic (CT) surgery. Because more surgeons are needed, we sought to investigate whether these events have affected recruitment and demographic change in the specialty between 1999 and 2014. We collected information on UK consultant CT surgeons using the SCTS public portal, the GMC Specialist Register and the NHS Annual Workforce Census via the Health & Social Care Information Centre. We analysed the demographics of UK CT surgeons with regard to country of primary medical qualification and ethnicity between 1999 and 2014. We compared the changes with other surgical specialties, cardiology and respiratory medicine. There has been a worrying decline in UK medical graduates entering the specialty and a 4-fold increase (282%) in consultant appointments from Europe. Whilst consultant numbers expanded by 83% overall, 59% of congenital heart surgeons, 46% of thoracic surgeons and 36% of adult cardiac surgeons are overseas graduates. It is found that 5% are female. Currently, only 32% of trainee surgeons are UK graduates. Of those receiving UK Certificate of Completion of Training in 2013, only 18% were UK graduates compared with 68% in 2000. Comparison with other specialties shows fewer UK graduates in CT surgery with the exception of Obstetrics and Gynaecology (52%). In cardiology, 77% are UK graduates with only 8% from Europe. Repeated negative messages have had a detrimental influence on recruitment. Because 55% of UK medical graduates, but less than 5% of CT surgeons are female, recruitment problems may worsen. Action is needed to restore interest in the specialty. © The Author 2015. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

  18. Aircraft trace gas measurements during the London 2012 Olympics: Air quality and emission fluxes derived from sampling upwind and downwind of a megacity

    Science.gov (United States)

    Allen, G.; O'Shea, S.; Muller, J.; Jones, B.; O'Sullivan, D.; Lee, J. D.; Bauguitte, S.; Gallagher, M. W.; Percival, C.; Barratt, B.; McQuaid, J. B.; Illingworth, S.

    2013-12-01

    This study presents airborne in situ and remote sensing measurements recorded during July and August 2012, across the period of the London 2012 Summer Olympics and simultaneous with the Clear air for London (ClearfLo) ground-based measurement and modelling campaign. Through long-term (2-year) and intensive observation periods (Winter 2011 and Summer 2012), the ClearfLo programme aims to better understand emissions, as well as the chemical, dynamical and micro-meteorological processes which modulate air quality in the London urban environment - an important risk factor for both acute and chronic health effects. The work presented here focuses on two contrasting case studies within the summer ClearfLo period: 30 July 2012 and 9 August 2012, representing relatively clean background and polluted background cases, respectively, and characterised by well-mixed Atlantic westerly maritime inflow in the former and stagnant air (high pressure) in the latter. Measurements of CO, CO2, CH4, N2O, O3, HCN, and other gases measured on board the UK Facility for Airborne Atmospheric Measurement (FAAM) BAe-146 aircraft will be presented and interpreted, with emphasis on observed concentration gradients and tracer-tracer correlations as well as airmass vertical structure and airmass history upwind and downwind of central London in each case. By applying a simple advective model and making use of vertically resolved thermodynamic and composition data, we are able to derive emission strengths for these gases that are representative of the total enclosed surface area. Example emissions for these two cases range between 6x105 kg(C)/hr and 9x105 kg(C)/hr for CO2, and ~0.6x105 kg(C)/hr for CH4. This airborne sampling methodology highlights the unique utility of aircraft measurements to routinely and climatologically characterise emissions from area sources such as cities, and points to future missions to target localised hotspots and distributed point sources.

  19. Clinical leadership development in postgraduate medical education and training: policy, strategy, and delivery in the UK National Health Service

    Directory of Open Access Journals (Sweden)

    Aggarwal R

    2015-11-01

    Full Text Available Reena Aggarwal,1,2 Tim Swanwick2 1Women's Health, Whittington Health, London, UK; 2Health Education England, North Central and East London, London, UK Abstract: Achieving high quality health care against a background of continual change, increasing demand, and shrinking financial resource is a major challenge. However, there is significant international evidence that when clinicians use their voices and values to engage with system delivery, operational efficiency and care outcomes are improved. In the UK National Health Service, the traditional divide between doctors and managers is being bridged, as clinical leadership is now foregrounded as an important organizational priority. There are 60,000 doctors in postgraduate training (junior doctors in the UK who provide the majority of front-line patient care and form an "operating core" of most health care organizations. This group of doctors is therefore seen as an important resource in initiating, championing, and delivering improvement in the quality of patient care. This paper provides a brief overview of leadership theories and constructs that have been used to develop a raft of interventions to develop leadership capability among junior doctors. We explore some of the approaches used, including competency frameworks, talent management, shared learning, clinical fellowships, and quality improvement. A new paradigm is identified as necessary to make a difference at a local level, which moves learning and leadership away from developing "leaders", to a more inclusive model of developing relationships between individuals within organizations. This shifts the emphasis from the development of a "heroic" individual leader to a more distributed model, where organizations are "leader-ful" and not just "well led" and leadership is centered on a shared vision owned by whole teams working on the frontline. Keywords: National Health Service, junior doctors, quality improvement, management, health care

  20. Paediatric UK demyelinating disease longitudinal study (PUDDLS

    Directory of Open Access Journals (Sweden)

    Likeman Marcus

    2011-07-01

    Full Text Available Abstract Background There is evidence that at least 5% of Multiple sclerosis (MS cases manifest in childhood. Children with MS present with a demyelinating episode involving single or multiple symptoms prior to developing a second event (usually within two years to then meet criteria for diagnosis. There is evidence from adult cohorts that the incidence and sex ratios of MS are changing and that children of immigrants have a higher risk for developing MS. A paediatric population should reflect the vanguard of such changes and may reflect trends yet to be observed in adult cohorts. Studying a paediatric population from the first demyelinating event will allow us to test these hypotheses, and may offer further valuable insights into the genetic and environmental interactions in the pathogenesis of MS. Methods/Design The Paediatric UK Demyelinating Disease Longitudinal Study (PUDDLS is a prospective longitudinal observational study which aims to determine the natural history, predictors and outcomes of childhood CNS inflammatory demyelinating diseases. PUDDLS will involve centres in the UK, and will establish a cohort of children affected with a first CNS inflammatory demyelinating event for long-term follow up by recruiting for approximately 5 years. PUDDLS will also establish a biological sample archive (CSF, serum, and DNA, allowing future hypothesis driven research. For example, the future discovery of a biomarker will allow validation within this dataset for the evaluation of novel biomarkers. Patients will also be requested to consent to be contacted in the future. A secondary aim is to collaborate internationally with the International Paediatric Multiple Sclerosis Study Group when future collaborative studies are proposed, whilst sharing a minimal anonymised dataset. PUDDLS is the second of two jointly funded studies. The first (UCID-SS is an epidemiological surveillance study that already received ethical approvals, and started on the 1st

  1. Multiple sclerosis in Japan appears to be a milder disease compared to the UK.

    Science.gov (United States)

    Piccolo, L; Kumar, G; Nakashima, I; Misu, T; Kong, Y; Wakerley, B; Ryan, S; Cavey, A; Fujihara, K; Palace, Jacqueline

    2015-01-01

    Multiple sclerosis (MS) is relatively common in the West, but rare in Japan. In the literature, there are few comparative data regarding disease severity throughout the world. The objective of this study was to compare disability in patients from a UK and a Japanese MS cohort. We retrospectively analysed the clinical features of patients with MS from a UK and Japanese MS centre. The Multiple Sclerosis Severity Score (MSSS), which adjusts the Expanded Disability Status Scale score according to disease duration, was used as a marker of disease severity. One thousand one hundred forty-eight UK patients and 104 Japanese patient were identified representing the relative national prevalence. Demographics and disease duration did not differ between the groups. Median MSSS was significantly different between the two groups (Japan 3.34 vs. UK 5.87, p UK (12.9%) than in the Japanese cohort (3%, p = 0.044). The majority of Japanese patients (83.7% vs. UK 17%) had been exposed to disease modifying treatments (DMTs). Exposure to DMTs did not show a significant effect on disability. In conclusion, this study suggests that MS in Japan may be associated with less disability than in UK. More Japanese patients were treated with DMTs. Differences in treatments do not seem to explain the disparity in disability severity. This suggests either genetic or environmental influences on disease severity.

  2. Dietary management of urea cycle disorders: UK practice.

    Science.gov (United States)

    Adam, S; Champion, H; Daly, A; Dawson, S; Dixon, M; Dunlop, C; Eardley, J; Evans, S; Ferguson, C; Jankowski, C; Lowry, S; MacDonald, A; Maritz, C; Micciche, A; Robertson, L; Stafford, J; Terry, A; Thom, R; van Wyk, K; Webster, D; White, F J; Wildgoose, J

    2012-08-01

    There is no published data describing UK dietary management of urea cycle disorders (UCD). The present study describes dietary practices in UK inherited metabolic disorder (IMD) centres. Cross-sectional data from 16 IMD centres were collected by a questionnaire describing the management of UCD patients on prescribed protein-restricted diets. One hundred and seventy-five patients [N-acetylglutamate synthase deficiency, n = 3; carbamoyl phosphate synthase deficiency (CPS), n = 8; ornithine transcarbamoylase deficiency (OTC), n = 75; citrullinaemia, n = 41; argininosuccinic aciduria (ASA), n = 36; arginase deficiency, n = 12] were reported; 70% (n = 123) aged 0-16 years; 30% (n = 52) >16 years. Prescribed median protein intake decreased with age (0-6 months: 2 g kg(-1) day(-1); 7-12 months: 1.6 g kg(-1) day(-1); 1-10 years: 1.3 g kg(-1) day(-1); 11-16 years: 0.9 g kg(-1) day(-1) and >16 years: 0.8 g kg(-1) day(-1)) with little variation between disorders. Adult protein prescription ranged 0.4-1.2 g kg(-1) day(-1) (40-60 g day(-1)). In the previous 2 years, 30% (n = 53) were given essential amino acid supplements (EAAs) (CPS, n = 2; OTC, n = 20; citrullinaemia, n = 15; ASA, n = 7; arginase deficiency, n = 9). EAAs were prescribed for low plasma quantitative essential amino acids (n = 13 centres); inadequate natural protein intake (n = 11) and poor metabolic control (n = 9). From diagnosis, one centre prescribed EAAs for all patients and one centre for severe defects only. Only 3% (n = 6) were given branch chain amino acid supplements. Enteral feeding tubes were used by 25% (n = 44) for feeds and 3% (n = 6) for medications. Oral energy supplements were prescribed in 17% (n = 30) of cases. In the UK, protein restriction based on World Health Organization 'safe intakes of protein', is the principle dietary treatment for UCD. EAA supplements are prescribed mainly on clinical need. Multicentre collaborative research is required to define optimal dietary treatments. © 2012

  3. Going home after infant cardiac surgery: a UK qualitative study.

    Science.gov (United States)

    Tregay, Jenifer; Wray, Jo; Crowe, Sonya; Knowles, Rachel; Daubeney, Piers; Franklin, Rodney; Barron, David; Hull, Sally; Barnes, Nick; Bull, Catherine; Brown, Katherine L

    2016-04-01

    To qualitatively assess the discharge processes and postdischarge care in the community for infants discharged after congenital heart interventions in the first year of life. Qualitative study using semistructured interviews and Framework Analysis. UK specialist cardiac centres and the services their patients are discharged to. Twenty-five cardiologists and nurses from tertiary centres, 11 primary and secondary health professionals and 20 parents of children who had either died after discharge or had needed emergency readmission. Participants indicated that going home with an infant after cardiac intervention represents a major challenge for parents and professionals. Although there were reported examples of good care, difficulties are exacerbated by inconsistent pathways and potential loss of information between the multiple teams involved. Written documentation from tertiary centres frequently lacks crucial contact information and contains too many specialist terms. Non-tertiary professionals and parents may not hold the information required to respond appropriately when an infant deteriorates, this contributing to the stressful experience of managing these infants at home. Where they exist, the content of formal 'home monitoring pathways' varies nationally, and families can find this onerous. Service improvements are needed for infants going home after cardiac intervention in the UK, focusing especially on enhancing mechanisms for effective transfer of information outside the tertiary centre and processes to assist with monitoring and triage of vulnerable infants in the community by primary and secondary care professionals. At present there is no routine audit for this stage of the patient journey. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  4. UK Hazard Assessment for a Laki-type Volcanic Eruption

    Science.gov (United States)

    Witham, Claire; Felton, Chris; Daud, Sophie; Aspinall, Willy; Braban, Christine; Loughlin, Sue; Hort, Matthew; Schmidt, Anja; Vieno, Massimo

    2014-05-01

    Following the impacts of the Eyjafjallajokull eruption in 2010, two types of volcanic eruption have been added to the UK Government's National Risk Register for Civil Emergencies. One of these, a large gas-rich volcanic eruption, was identified as a high impact natural hazard, one of the three highest priority natural hazards faced by the UK. This eruption scenario is typified by the Laki eruption in Iceland in 1783-1784. The Civil Contingency Secretariat (CCS) of the UK's Cabinet Office, responsible for Civil Protection in the UK, has since been working on quantifying the risk and better understanding its potential impacts. This involves cross-cutting work across UK Government departments and the wider scientific community in order to identify the capabilities needed to respond to an effusive eruption, to exercise the response and develop increased resilience where possible. As part of its current work, CCS has been working closely with the UK Met Office and other UK agencies and academics (represented by the co-authors and others) to generate and assess the impacts of a 'reasonable worst case scenario', which can be used for decision making and preparation in advance of an eruption. Information from the literature and the findings of an expert elicitation have been synthesised to determine appropriate eruption source term parameters and associated uncertainties. This scenario is then being used to create a limited ensemble of model simulations of the dispersion and chemical conversion of the emissions of volcanic gases during such an eruption. The UK Met Office's NAME Lagrangian dispersion model and the Centre for Ecology and Hydrology's EMEP4UK Eulerian model are both being used. Modelling outputs will address the likelihood of near-surface concentrations of sulphur and halogen species being above specified health thresholds. Concentrations at aviation relevant altitudes will also be evaluated, as well as the effects of acid deposition of volcanic species on

  5. A qualitative study exploring parental accounts of feeding pre-school children in two low-income populations in the UK.

    Science.gov (United States)

    Hayter, Arabella K M; Draper, Alizon K; Ohly, Heather R; Rees, Gail A; Pettinger, Clare; McGlone, Pauline; Watt, Richard G

    2015-07-01

    Good nutrition in the early years of life is essential, yet the diets of many pre-school children in the UK are known to be poor. Understanding the decisions parents make when feeding young children is very important in determining what type and nature of interventional support may be developed to promote good nutrition. The aim of this study was to explore using qualitative methods, parental perceptions of feeding their children in order to inform the development of a nutrition intervention. Focus groups (n = 33) and individual interviews (n = 6) were undertaken with parents, most of whom were attending children's centres in two deprived populations from one urban (Islington, north London) and one rural (Cornwall) location in England. Accounts of feeding pre-school children were primarily concerned with dealing with the practicalities of modern life, in particular the cost of food and the need to manage on a restricted household budget. Time pressures, a lack of perceived knowledge and confidence in preparing food and managing conflict over food choices between family members were also strong themes. Parents commonly reported differences between how they would like to feed their children and the reality of what they were able to do in their circumstances. These findings suggest that the poor eating habits of many pre-school children may be less a case of parental ignorance but rather the product of a range of coping strategies. Designing an intervention, which helps parents to build their confidence and self-efficacy, may enable them to make positive changes to their children's diets. © 2013 Blackwell Publishing Ltd.

  6. UK malaria treatment guidelines 2016.

    Science.gov (United States)

    Lalloo, David G; Shingadia, Delane; Bell, David J; Beeching, Nicholas J; Whitty, Christopher J M; Chiodini, Peter L

    2016-06-01

    1.Malaria is the tropical disease most commonly imported into the UK, with 1300-1800 cases reported each year, and 2-11 deaths. 2. Approximately three quarters of reported malaria cases in the UK are caused by Plasmodium falciparum, which is capable of invading a high proportion of red blood cells and rapidly leading to severe or life-threatening multi-organ disease. 3. Most non-falciparum malaria cases are caused by Plasmodium vivax; a few cases are caused by the other species of plasmodium: Plasmodium ovale, Plasmodium malariae or Plasmodium knowlesi. 4. Mixed infections with more than one species of parasite can occur; they commonly involve P. falciparum with the attendant risks of severe malaria. 5. There are no typical clinical features of malaria; even fever is not invariably present. Malaria in children (and sometimes in adults) may present with misleading symptoms such as gastrointestinal features, sore throat or lower respiratory complaints. 6. A diagnosis of malaria must always be sought in a feverish or sick child or adult who has visited malaria-endemic areas. Specific country information on malaria can be found at http://travelhealthpro.org.uk/. P. falciparum infection rarely presents more than six months after exposure but presentation of other species can occur more than a year after exposure. 7. Management of malaria depends on awareness of the diagnosis and on performing the correct diagnostic tests: the diagnosis cannot be excluded until more than one blood specimen has been examined. Other travel related infections, especially viral haemorrhagic fevers, should also be considered. 8. The optimum diagnostic procedure is examination of thick and thin blood films by an expert to detect and speciate the malarial parasites. P. falciparum and P. vivax (depending upon the product) malaria can be diagnosed almost as accurately using rapid diagnostic tests (RDTs) which detect plasmodial antigens. RDTs for other Plasmodium species are not as reliable. 9

  7. Assessment of micro-scale anaerobic digestion for management of urban organic waste: A case study in London, UK.

    Science.gov (United States)

    Walker, M; Theaker, H; Yaman, R; Poggio, D; Nimmo, W; Bywater, A; Blanch, G; Pourkashanian, M

    2017-03-01

    This paper describes the analysis of an AD plant that is novel in that it is located in an urban environment, built on a micro-scale, fed on food and catering waste, and operates as a purposeful system. The plant was built in 2013 and continues to operate to date, processing urban food waste and generating biogas for use in a community café. The plant was monitored for a period of 319days during 2014, during which the operational parameters, biological stability and energy requirements of the plant were assessed. The plant processed 4574kg of food waste during this time, producing 1008m(3) of biogas at average 60.6% methane. The results showed that the plant was capable of stable operation despite large fluctuations in the rate and type of feed. Another innovative aspect of the plant was that it was equipped with a pre-digester tank and automated feeding, which reduced the effect of feedstock variations on the digestion process. Towards the end of the testing period, a rise in the concentration of volatile fatty acids and ammonia was detected in the digestate, indicating biological instability, and this was successfully remedied by adding trace elements. The energy balance and coefficient of performance (COP) of the system were calculated, which concluded that the system used 49% less heat energy by being housed in a greenhouse, achieved a net positive energy balance and potential COP of 3.16 and 5.55 based on electrical and heat energy, respectively. Greenhouse gas emissions analysis concluded that the most important contribution of the plant to the mitigation of greenhouse gases was the avoidance of on-site fossil fuel use, followed by the diversion of food waste from landfill and that the plant could result in carbon reduction of 2.95kg CO2eq kWh(-1) electricity production or 0.741kg CO2eq kg(-1) waste treated. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Pharma Pricing & Market Access Europe 2016--Health Network Communications' Tenth Annual Conference (February 23-25, 2016--London, UK).

    Science.gov (United States)

    D'Souza, P

    2016-03-01

    Tighter national budgets and escalating drug prices continue to present challenges for pharmaceutical market access strategies and societal cost of care. As pharmaceutical companies and medical governmental advisory organizations enter tougher negotiations, hospital trusts and other dispensary firms face barriers to receiving the best medical treatment, and as a result patient access is limited. The 2016 HealthNetwork Communications' Pharma Pricing & Market Access Europe meeting brought together pharmaceutical, medical governmental advisory and stakeholders and market access/pricing consultants, to encourage discussions and negotiations into how to improve the drug pricing system and consequential market access strategies while achieving the respective reimbursement and affordability objectives. Copyright 2016 Prous Science, S.A.U. or its licensors. All rights reserved.

  9. AVSS 2007: IEEE International Conference onAdvanced Video and Signal based Surveillance, London, UK, September 2007

    DEFF Research Database (Denmark)

    Fihl, Preben

    This technical report will cover the participation in the IEEE International Conference on Advanced Video and Signal based Surveillance in September 2007. The report will give a concise description of the most relevant topics presented at the conference, focusing on the work related to the HERMES...

  10. Trust, Autonomy and Relationships: The Help-Seeking Preferences of Young People in Secondary Level Schools in London (UK)

    Science.gov (United States)

    Leavey, Gerard; Rothi, Despina; Paul, Rini

    2011-01-01

    Help-seeking among young people is complicated, often determined vicariously by the ability of adults, family or professionals, to recognize, and respond to, their difficulties. We know very little about the complex concerns of teenage young people and how they impact on help-seeking preferences. We aimed to ascertain the help-seeking preferences…

  11. The Particle Physicists’ Song : the CERN Choir in full voice in the CERN Control Centre, with writer Danuta Orlowska

    CERN Multimedia

    Maximilien Brice

    2010-01-01

    The song was submitted to CERN Courier by Danuta Orlowska, a clinical psychologist with Guy’s and St Thomas’ NHS Foundation Trust in London. It is written to be sung to the tune of The Hippopotamus Song, by Michael Flanders and Donald Swann, which will be well known to many British readers. On 3 February, members of the CERN choir gathered to give a rendition in the CERN Control Centre – the nerve centre of the LHC, which lies at the heart of the lyrics.

  12. Council celebrates CERN Control Centre

    CERN Multimedia

    2006-01-01

    With the unveiling of its new sign, the CERN Control Centre was officially inaugurated on Thursday 16 March. To celebrate its startup, CERN Council members visited the sleek centre, a futuristic-looking room filled with a multitude of monitoring screens.

  13. An exploratory study of information sources and key findings on UK cocaine-related deaths.

    Science.gov (United States)

    Corkery, John M; Claridge, Hugh; Goodair, Christine; Schifano, Fabrizio

    2017-08-01

    Cocaine-related deaths have increased since the early 1990s in Europe, including the UK. Being multi-factorial, they are difficult to define, detect and record. The European Monitoring Centre for Drugs and Drug Addiction commissioned research to: describe trends reported to Special Mortality Registries and General Mortality Registers; provide demographic and drug-use characteristic information of cases; and establish how deaths are identified and classified. A questionnaire was developed and piloted amongst all European Monitoring Centre for Drugs and Drug Addiction Focal Point experts/Special Mortality Registries: 19 (63%) responded; nine countries provided aggregated data. UK General Mortality Registers use cause of death and toxicology to identify cocaine-related deaths. Categorisation is based on International Classification of Diseases codes. Special Mortality Registries use toxicology, autopsy, evidence and cause of death. The cocaine metabolites commonly screened for are: benzoylecgonine, ecgonine methyl ester, cocaethylene and ecgonine. The 2000s saw a generally accelerating upward trend in cases, followed by a decline in 2009. The UK recorded 2700-2900 deaths during 1998-2012. UK Special Mortality Registry data (2005-2009) indicate: 25-44 year-olds account for 74% of deaths; mean age=34 (range 15-81) years; 84% male. Cocaine overdoses account for two-thirds of cases; cocaine alone being mentioned/implicated in 23% in the UK. Opioids are involved in most (58%) cocaine overdose cases.

  14. Lessons for climate policy from The Great Stink of London

    Science.gov (United States)

    Skuce, A.

    2012-12-01

    A rapidly growing population and the introduction of the flush toilet in nineteenth-century London caused a crisis with sewage pollution in the River Thames (Halliday, 1999). There were decades of delays in implementing solutions owing to: inadequate governance institutions; political inertia; difficulties with financing; opposition from vested interests; scientific uncertainties; and technological challenges. Effective counter-measures were started only once the problem arose, quite literally, under the noses of parliamentarians. There are parallels, some of them pointed out earlier by Alley et al (2010), between the sewage crisis in Victorian London and the current problem with climate change. Both involve the unsustainable use of a common resource (a river, the atmosphere) for the unconstrained disposal of human waste products. Alley (2011) estimated that the costs of providing clean water and sanitation are comparable to the expected costs of reducing greenhouse gas emissions. Despite the similarities, the climate change issue is actually much more difficult because of: a) the unequal and uncertain global distribution of cause and effect; b) its long, intergenerational time lines; c) the insufficiency of adequate institutions, conventions or the tools— political, moral or economic—for tackling the climate crisis. This analysis is consistent with the model proposed by Gardiner (2011) in his book A Perfect Moral Storm. The three "storms" he identifies, the global, intergenerational and theoretical storms, combine in a powerful synergy to create a challenge of unprecedented intractability, providing opportunities for what Gardiner calls moral corruption: the obscuring of the buck-passing and procrastination that characterizes climate policy today. In Victorian London, the crucial steps to solve the sewage crises were not taken until the stench from the River Thames during the hot summer of 1858 rendered the House of Commons uninhabitable. A greater stink of a

  15. Two daily smoke maxima in eighteenth century London air

    Science.gov (United States)

    Harrison, R. Giles

    Varied electrostatics experiments followed Benjamin Franklin's pioneering atmospheric investigations. In Knightsbridge, Central London, John Read (1726-1814) installed a sensing rod in the upper part of his house and, using a pith ball electrometer and Franklin chimes, monitored atmospheric electricity from 1789 to 1791. Atmospheric electricity is sensitive to weather and smoke pollution. In calm weather conditions, Read observed two daily electrification maxima in moderate weather, around 9 am and 7 pm. This is likely to represent a double diurnal cycle in urban smoke. Before the motor car and steam railways, one source of the double maximum smoke pattern was the daily routine of fire lighting for domestic heating.

  16. The psychological and psychiatric effects of terrorism: lessons from London.

    Science.gov (United States)

    Rubin, G James; Wessely, Simon

    2013-09-01

    The 7 July 2005 bombings in London caused heightened levels of distress among some in the general community. This distress was most notable in Muslims and members of ethnic minority groups. These effects were transient for most. An estimated 30% of those who were more affected by the attacks, including victims and witnesses, developed psychiatric disorders as a result. An outreach program was set up to screen those who were exposed to potentially traumatic events and to offer them evidence-based treatment. This article discusses what lessons might be learned from studies of the general community and the screen-and-treat approach. Copyright © 2013 Elsevier Inc. All rights reserved.

  17. Stylistic Analysis of William Blake’s Poem London

    Institute of Scientific and Technical Information of China (English)

    陈杨波

    2014-01-01

    William Blake utilized ingenious language in his creation of the poem London. Foregrounding and deviation are well practised in this poem. In rhyme pattern, the poem takes end rhyme, consonance, alliteration and internal rhyme. In rhythm pat-tern, the poem mainly uses iambic tetrameter along with the variation of three troches and one single stress at the end of lines which produces a shocking atmosphere. Among syntax features, emphatic pattern and anticipatory structure are used. Among lexi-cal features, the reiteration of specific words makes neat euphonious parallelism while the subtle pun word create a far-reaching artistry.

  18. Regeneralized London free energy for high-Tc vortex lattices

    Directory of Open Access Journals (Sweden)

    M. A. Shahzamanian

    2006-09-01

    Full Text Available   The London free-energy is regeneralized by the Ginsburg-Landau free-energy density in the presence of both d and s order parameters. We have shown that the strength of the s-d coupling, makes an important rule to determine the form of the lattice vortex. Appearance of the ratios of the coherence length to penetration depth in the higher order corrections of the free-energy density will truncate these corrections for even large values of .

  19. Carrington-L5: The UK/US Space Weather Operational Mission.

    Science.gov (United States)

    Bisi, M. M.; Trichas, M.

    2015-12-01

    Airbus Defence and Space (UK) have carried out a study for an operational L5 space weather mission, in collaboration with RAL, the UK Met Office, UCL and Imperial College London. The study looked at the user requirements for an operational mission, a model instrument payload, and a mission/spacecraft concept. A particular focus is cost effectiveness and timelineness of the data, suitable for operational forecasting needs. The study focussed on a mission at L5 assuming that a US mission to L1 will already occur, on the basis that L5 offers the greatest benefit for SWE predictions. The baseline payload has been selected to address all MOSWOC/SWPC priorities using UK/US instruments, consisting of: a heliospheric imager, coronagraph, EUV imager, magnetograph, magnetometer, solar wind analyser and radiation monitor. The platform is based on extensive re-use from Airbus' past missions to minimize the cost and a Falcon-9 launcher has been selected on the same basis. A schedule analysis shows that the earliest launch could occur in 2020, assuming Phase A KO in 2015. The study team have selected the name "Carrington" for the mission, reflecting the UK's proud history in this domain.

  20. Balancing Fear: Why Counter-Terror Legislation was Blocked after the Oklahoma City and London Bombings

    Directory of Open Access Journals (Sweden)

    Gabriel Rubin

    2010-11-01

    executive approval ratings are critical to the passage of counter-terror laws.  In light of the recent slew of counter-terror legislation passed worldwide, cases where counter-terror legislation has been blocked have become critically important.  To this end, this article asks, “Why does counter-terror legislation get blocked when it does?”  To answer the question, three variables are tested: partisan composition of the government, public opinion-based mass fear levels, and executive approval ratings.  To test the variables, two cases are evaluated: the passage of diluted counter-terror legislation after the Oklahoma City Bombing in 1995 and after the 2005 London Bombings.  In evaluating the cases, legislative debates and executive statements that occurred after the terror attacks are examined and then compared to cases from the UK in 1974 and the US in 2001 where counter-terror legislation quickly passed.  The article concludes that executive approval ratings and the partisan composition of the government have the most explanatory power in determining whether terror attacks will lead to broad counter-terror legislation or not.Keywords: London bombings; counter-terror legislation; USA; United Kingdom

  1. Balancing Fear: Why Counter-Terror Legislation was Blocked after the Oklahoma City and London Bombings

    Directory of Open Access Journals (Sweden)

    Gabriel Rubin

    2010-11-01

    executive approval ratings are critical to the passage of counter-terror laws.  In light of the recent slew of counter-terror legislation passed worldwide, cases where counter-terror legislation has been blocked have become critically important.  To this end, this article asks, “Why does counter-terror legislation get blocked when it does?”  To answer the question, three variables are tested: partisan composition of the government, public opinion-based mass fear levels, and executive approval ratings.  To test the variables, two cases are evaluated: the passage of diluted counter-terror legislation after the Oklahoma City Bombing in 1995 and after the 2005 London Bombings.  In evaluating the cases, legislative debates and executive statements that occurred after the terror attacks are examined and then compared to cases from the UK in 1974 and the US in 2001 where counter-terror legislation quickly passed.  The article concludes that executive approval ratings and the partisan composition of the government have the most explanatory power in determining whether terror attacks will lead to broad counter-terror legislation or not.Keywords: London bombings; counter-terror legislation; USA; United Kingdom

  2. Recording of hospitalizations for acute exacerbations of COPD in UK electronic health care records

    Directory of Open Access Journals (Sweden)

    Rothnie KJ

    2016-11-01

    Full Text Available Kieran J Rothnie,1,2 Hana Müllerová,3 Sara L Thomas,2 Joht S Chandan,4 Liam Smeeth,2 John R Hurst,5 Kourtney Davis,3 Jennifer K Quint1,2 1Respiratory Epidemiology, Occupational Medicine and Public Health, National Heart and Lung Institute, Imperial College London, London, UK; 2Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK; 3Respiratory Epidemiology, GlaxoSmithKline R&D, Uxbridge, London; 4Medical School, 5UCL Respiratory, University College London, London, UK Background: Accurate identification of hospitalizations for acute exacerbations of chronic obstructive pulmonary disease (AECOPD within electronic health care records is important for research, public health, and to inform health care utilization and service provision. We aimed to develop a strategy to identify hospitalizations for AECOPD in secondary care data and to investigate the validity of strategies to identify hospitalizations for AECOPD in primary care data. Methods: We identified patients with chronic obstructive pulmonary disease (COPD in the Clinical Practice Research Datalink (CPRD with linked Hospital Episodes Statistics (HES data. We used discharge summaries for recent hospitalizations for AECOPD to develop a strategy to identify the recording of hospitalizations for AECOPD in HES. We then used the HES strategy as a reference standard to investigate the positive predictive value (PPV and sensitivity of strategies for identifying AECOPD using general practice CPRD data. We tested two strategies: 1 codes for hospitalization for AECOPD and 2 a code for AECOPD other than hospitalization on the same day as a code for hospitalization due to unspecified reason. Results: In total, 27,182 patients with COPD were included. Our strategy to identify hospitalizations for AECOPD in HES had a sensitivity of 87.5%. When compared with HES, using a code suggesting hospitalization for AECOPD in CPRD resulted in a PPV of 50.2% (95

  3. Creating a no-blame culture through medical education: a UK perspective

    Directory of Open Access Journals (Sweden)

    Elmqvist KO

    2016-08-01

    Full Text Available Karl O Elmqvist,1 Maxime TJ Rigaudy,1,2 Jasper P Vink1 1Imperial College Business School, Imperial College London, London, UK; 2Hull York Medical School, York, UK We read with great interest, and agree with the points made, in the Commentary by Leotsakos et al1 regarding the need to integrate patient safety into the core curricula for higher education in health care. The World Health Organisation (WHO patient safety curriculum guide: multi-professional edition (Geneva: Switzerland 2011 appears to be an effective aid to achieve this aim, promoting the culture of patient safety internationally. In the UK, where patient safety is a defining part of quality of care,2 attempts have been made to introduce the concept of a “no-blame culture”. The no-blame culture was introduced as a method to improve the quality of care by learning from mistakes, putting safeguards in place to ensure they do not occur again.  View the original paper by Leotsakos and colleagues.

  4. Processing LHC data in the UK.

    Science.gov (United States)

    Colling, D; Britton, D; Gordon, J; Lloyd, S; Doyle, A; Gronbech, P; Coles, J; Sansum, A; Patrick, G; Jones, R; Middleton, R; Kelsey, D; Cass, A; Geddes, N; Clark, P; Barnby, L

    2013-01-28

    The Large Hadron Collider (LHC) is one of the greatest scientific endeavours to date. The construction of the collider itself and the experiments that collect data from it represent a huge investment, both financially and in terms of human effort, in our hope to understand the way the Universe works at a deeper level. Yet the volumes of data produced are so large that they cannot be analysed at any single computing centre. Instead, the experiments have all adopted distributed computing models based on the LHC Computing Grid. Without the correct functioning of this grid infrastructure the experiments would not be able to understand the data that they have collected. Within the UK, the Grid infrastructure needed by the experiments is provided by the GridPP project. We report on the operations, performance and contributions made to the experiments by the GridPP project during the years of 2010 and 2011--the first two significant years of the running of the LHC.

  5. CMCC Data Distribution Centre

    Science.gov (United States)

    Aloisio, Giovanni; Fiore, Sandro; Negro, A.

    2010-05-01

    The CMCC Data Distribution Centre (DDC) is the primary entry point (web gateway) to the CMCC. It is a Data Grid Portal providing a ubiquitous and pervasive way to ease data publishing, climate metadata search, datasets discovery, metadata annotation, data access, data aggregation, sub-setting, etc. The grid portal security model includes the use of HTTPS protocol for secure communication with the client (based on X509v3 certificates that must be loaded into the browser) and secure cookies to establish and maintain user sessions. The CMCC DDC is now in a pre-production phase and it is currently used only by internal users (CMCC researchers and climate scientists). The most important component already available in the CMCC DDC is the Search Engine which allows users to perform, through web interfaces, distributed search and discovery activities by introducing one or more of the following search criteria: horizontal extent (which can be specified by interacting with a geographic map), vertical extent, temporal extent, keywords, topics, creation date, etc. By means of this page the user submits the first step of the query process on the metadata DB, then, she can choose one or more datasets retrieving and displaying the complete XML metadata description (from the browser). This way, the second step of the query process is carried out by accessing to a specific XML document of the metadata DB. Finally, through the web interface, the user can access to and download (partially or totally) the data stored on the storage device accessing to OPeNDAP servers and to other available grid storage interfaces. Requests concerning datasets stored in deep storage will be served asynchronously.

  6. Analysis on Jack London's Feminist Point of View in Martin Eden

    Institute of Scientific and Technical Information of China (English)

    陈俊汀

    2016-01-01

    Martin Eden is one of the famous novels of Jack London, who is a distinguished writer in America, and now it still wins great popularity in the whole world. In this novel, the author Jack London depicts the protagonist Martin Eden's striving for success incisively. This thesis, based on the theory of feminism, will give a detailed analysis of the character traits of female characters in Martin Eden and Jack London's attitudes towards women.

  7. ""Thames Valley cotton pickers"": Race and youth in London blues culture

    OpenAIRE

    2005-01-01

    This study addresses the reception of African American blues music and the ensuing production of English blues in London from 1955 to 1966. It concentrates on London adolescents' unexpected fascination with a musical style that they virtually had no contact with prior to 1955, while analyzing how this immersion in African American culture shaped their cultural identity. Analysis of the influence of African American blues music in London during this period highlights the BBC's weakened influen...

  8. The Cleft Care UK study. Part 4: perceptual speech outcomes

    Science.gov (United States)

    Sell, D; Mildinhall, S; Albery, L; Wills, A K; Sandy, J R; Ness, A R

    2015-01-01

    Structured Abstract Objectives To describe the perceptual speech outcomes from the Cleft Care UK (CCUK) study and compare them to the 1998 Clinical Standards Advisory Group (CSAG) audit. Setting and sample population A cross-sectional study of 248 children born with complete unilateral cleft lip and palate, between 1 April 2005 and 31 March 2007 who underwent speech assessment. Materials and methods Centre-based specialist speech and language therapists (SLT) took speech audio–video recordings according to nationally agreed guidelines. Two independent listeners undertook the perceptual analysis using the CAPS-A Audit tool. Intra- and inter-rater reliability were tested. Results For each speech parameter of intelligibility/distinctiveness, hypernasality, palatal/palatalization, backed to velar/uvular, glottal, weak and nasalized consonants, and nasal realizations, there was strong evidence that speech outcomes were better in the CCUK children compared to CSAG children. The parameters which did not show improvement were nasal emission, nasal turbulence, hyponasality and lateral/lateralization. Conclusion These results suggest that centralization of cleft care into high volume centres has resulted in improvements in UK speech outcomes in five-year-olds with unilateral cleft lip and palate. This may be associated with the development of a specialized workforce. Nevertheless, there still remains a group of children with significant difficulties at school entry. PMID:26567854

  9. Impact of UK Building Regulations on design and thermal performance of dwellings

    Institute of Scientific and Technical Information of China (English)

    LIM; D; 姚润明

    2009-01-01

    This paper looks at the progressive impact of UK Building Regulations (Part L) on the energy consumption of dwellings with respect to thermal performance of the building envelope. It provides an overview of building legislation,highlighting progressive improvement in building elemental U-values and compliance methods. The focus centres on Building Regulations from 1965 to 2006,at a time when energy conservation has become an integral component of building control due to environmental concerns. Simulation software is used to compare energy consumption for 5 typical UK dwelling types through a series of case studies which illustrate the rate of impact over recent years.

  10. Liquidity, price impact and trade informativeness: Evidence from the London stock exchange

    National Research Council Canada - National Science Library

    Teodorovic, Natasa

    2011-01-01

    ...) market microstructure time series analysis to examine adverse selection and information asymmetry issues on diverse liquidity leveled stocks listed on the London Stock Exchange, which is a market...

  11. The international follow-up of individuals potentially exposed to polonium-210 in London 2006.

    Science.gov (United States)

    Shaw, K; Anders, K; Olowokure, B; Fraser, G; Maguire, H; Bailey, M; Smith, J; Frossell, S; Yap, K; Evans, B

    2010-06-01

    Following a death from polonium-210 ((210)Po), contamination was found at several sites in London. This paper describes the UK Health Protection Agency's follow-up and assessment of individuals resident overseas who were potentially exposed to (210)Po. Descriptive follow-up study. Individuals were classified into three exposure groups (higher, lower and unknown). Presence and degree of internal contamination were measured by 24-h urinary (210)Po activity (mBq/day). Results over 30mBq/day were taken to indicate probable contact with (210)Po in this incident. Dose assessments were conducted to determine degree of exposure and to identify individuals requiring further follow-up. Overall, 664 potentially exposed persons from 52 countries and territories were identified. Of these, 157 (24%) were in the higher exposure category, and urinary measurements were reported for 31% (48/157). Results for 19% (9/48) of those at higher exposure were more than 30mBq/day. For those at lower exposure, the percentage was 4% (3/68). Results above 30mBq/day were significantly more likely to be reported for the higher exposure category than the lower exposure category (Fisher's exact test P=0.010). Reported dose assessments suggested that identified individuals were not at increased health risk in the long term. Challenges and practical lessons were identified during the investigation. The results suggest that it is unlikely that any overseas resident had significant internal contamination with (210)Po. However, this incident clearly demonstrated the scale of international involvement likely to be necessary in other public health emergencies in large cities. The lessons identified have implications for the international health community, particularly with regard to the follow-up of individuals exposed to radiation in one country who then travel to another. Copyright 2010 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  12. Space-Time Analysis of Crime Patterns in Central London

    Science.gov (United States)

    Cheng, T.; Williams, D.

    2012-07-01

    Crime continues to cast a shadow over citizen well-being in big cities today, while also imposing huge economic and social costs. Timely understanding of how criminality emerges and how crime patterns evolve is crucial to anticipating crime, dealing with it when it occurs and developing public confidence in the police service. Every day, about 10,000 crime incidents are reported by citizens, recorded and geo-referenced in the London Metropolitan Police Service Computer Aided Dispatch (CAD) database. The unique nature of this dataset allows the patterns to be explored at particularly fine temporal granularity and at multiple spatial resolutions. This study provides a framework for the exploratory spatio-temporal analysis of crime patterns that combines visual inquiry tools (interactive animations, space-time cubes and map matrices) with cluster analysis (spatial-temporal scan statistics and the self-organizing map). This framework is tested on the CAD dataset for the London Borough of Camden in March 2010. Patterns of crime through space and time are discovered and the clustering methods were evaluated on their ability to facilitate the discovery and interpretation of these patterns.

  13. Carbon Capture and Storage and the London Protocol

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The International Energy Agency (IEA) estimates that 100 Carbon Capture and Storage (CCS) projects will be required by 2020 and over 3000 by 2050 if CCS is to contribute fully to the least-cost technology portfolio for CO2 mitigation. For CCS to reach its emissions reduction potential, the 2009 IEA publication Technology Roadmap: Carbon Capture and Storage recommends that international legal obstacles associated with global CCS deployment be removed by 2012 -- including the prohibition on transboundary CO2 transfer under the London Protocol. The London Protocol was amended by contracting parties in 2009 to allow for cross-border transportation of CO2 for sub-seabed storage, but the amendment must be ratified by two-thirds of contracting parties to enter into force. It is unlikely that this will occur in the near term; this working paper therefore outlines options that may be available to contracting parties under international law to address the barrier to deployment presented by Article 6, pending formal entry into force of the 2009 amendment.

  14. Ethnic inequalities in dental caries among adults in East London.

    Science.gov (United States)

    Delgado-Angulo, Elsa K; Bernabé, Eduardo; Marcenes, Wagner

    2016-06-01

    This study explored ethnic inequalities in dental caries among adults and assessed the role of socioeconomic position (SEP) in explaining those inequalities. We analysed data on 2013 adults aged 16-65 years, from the East London Oral Health Inequality (ELOHI) Study, which included a random sample of adults and children living in East London in 2009-10. Participants completed a questionnaire and were clinically examined for dental caries at home. Dental caries was measured using the number of decayed, missing and filled teeth or DMFT index. Ethnic inequalities in dental caries were assessed in negative binomial regression models before and after adjustment for demographic (sex and age groups) and SEP measures (education and socioeconomic classification). White Eastern European and White Other had higher DMFT, whereas all Asian (Pakistani, Indian, Bangladeshi and Other) and all Black (African, Caribbean and Other) ethnic groups had lower DMFT than White British. Similar inequalities were found for the number of filled and missing teeth, but there were no differences in the number of decayed teeth between ethnic groups. This study showed considerable disparities in dental caries between and within the major ethnic categories, which were independent of demographics and SEP. © The Author 2015. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  15. CT colonography practice in the UK: a national survey

    Energy Technology Data Exchange (ETDEWEB)

    Burling, D.; Halligan, S. E-mail: s.halligan@imperial.ac.uk; Taylor, S.A.; Usiskin, S.; Bartram, C.I

    2004-01-01

    AIM: To determine the provision of computed tomography (CT) colonography in UK radiology departments. MATERIALS AND METHODS: A questionnaire relating to the availability of CT colonography, barriers to implementation, clinical indications, technique, and practitioners was posted to clinical directors of UK radiology departments. RESULTS: One hundred and thirty-eight departments responded. Fifty (36%) offered CT colonography in day-to-day clinical practice. Of those that did not, 68 of 87 (64%) cited limited scanner capacity as the main barrier. Of the 50 departments offering a service, 39 (78%) offered CT after incomplete colonoscopy, 36 (72%), after failed barium enema, and 37 (74%) as an alternative to barium enema. Of those offering a service, the number of studies performed varied between one per month (38%) to more than one per day (8%). Total experience varied between 20 or fewer studies (28%) to more than 300 (12%). Full bowel preparation was common (92%), as was dual positioning (90%). Colonography was interpreted by radiologists with a subspecialty interest in gastrointestinal imaging in 64% of centres offering a service. CONCLUSION: CT colonography is widely available in the UK, with approximately one-third of responders offering a service. Experience and throughput varies considerably. Limited CT scanner capacity is the major barrier to further dissemination.

  16. Visit of UK Prime Minister

    CERN Multimedia

    1982-01-01

    Wolfgang Schnell shows a prototype LEP r.f. accelerating cavity with a superposed storage cavity to U.K. Head of Government Mrs.Margareth Thatcher during her visit to CERN. Behind Mrs.Thatcher one can see CERN Director General Herwig Schopper.

  17. The UK Prospective Diabetes Study

    DEFF Research Database (Denmark)

    Olivarius, Niels de Fine; Andreasen, A.H.

    1998-01-01

    Læserbrev, som kritiserer det store UK Prospective Diabetes Study's forfattere for at overfortolke deres fund, idet marginalt signifikante p-værdier tages som udtryk for slående effekt (af at sænke blodsukkeret). Det sker selvom der f.eks. indgår effektvariabler, som kunne påvirkes af patienternes...

  18. Teaching Astronomy in UK Schools

    Science.gov (United States)

    Roche, Paul; Roberts, Sarah; Newsam, Andy; Barclay, Charles

    2012-01-01

    This article attempts to summarise the good, bad and (occasionally) ugly aspects of teaching astronomy in UK schools. It covers the most common problems reported by teachers when asked about covering the astronomy/space topics in school. Particular focus is given to the GCSE Astronomy qualification offered by Edexcel (which is currently the…

  19. Teaching Astronomy in UK Schools

    Science.gov (United States)

    Roche, Paul; Roberts, Sarah; Newsam, Andy; Barclay, Charles

    2012-01-01

    This article attempts to summarise the good, bad and (occasionally) ugly aspects of teaching astronomy in UK schools. It covers the most common problems reported by teachers when asked about covering the astronomy/space topics in school. Particular focus is given to the GCSE Astronomy qualification offered by Edexcel (which is currently the…

  20. "UK today" Tallinnas / Tuuli Oder

    Index Scriptorium Estoniae

    Oder, Tuuli

    2001-01-01

    Vabariikliku inglise keele olümpiaadi raames toimus 9. nov.̀2001 Tallinnas viktoriini "UK today" lõppvoor, mille korraldas üleriigiline inglise keele ainenõukogu. Osalesid 22 kooli kaheliikmelised võistkonnad. Viktoriini tulemused koolide lõikes ja küsimused õigete vastustega

  1. UK Open Access Policy Landscape

    OpenAIRE

    Picarra, Mafalda

    2014-01-01

    Two distinct paths for open access are being promoted in UK open access policies: open access publishing (gold open access) by RCUK (Gold OA) and self-archiving (green open access) by HEFCE. This requires continuous and coordinated efforts to support universities, academic libraries and researchers in achieving compliance.

  2. Minister unveils new nanotech centres

    Science.gov (United States)

    Dumé, Belle

    2009-06-01

    Three new nanotechnology research centres are to be set up in France as part of a €70m government plan to help French companies in the sector. Researchers at the new centres, which will be located in Grenoble, Saclay (near Paris) and Toulouse, will be encouraged to collaborate with industry to develop new nanotech-based products. Dubbed NANO-INNOV, the new plan includes €46m for two new buildings at Saclay, with the rest being used to buy new equipment at the three centres and to fund grant proposals from staff to the French National Research Agency (ANR).

  3. 25 years Nuclear Research Centre

    Energy Technology Data Exchange (ETDEWEB)

    Harde, R.

    1981-07-01

    On June 12, the Karlsruhe Nuclear Research Centre celebrated its 25th anniversary. The Centre was founded on July 19, 1956. The importance of this institution became apparent by the large number of prominent guests, at the head, the Federal President, Karl Carstens. Minister President Spaeth and the Federal Minister for Research and Technology, von Buelow, appreciated the achievements obtained by this big science centre of nuclear technology. The ceremony held in the State theatre of Baden-Wuerttemberg gave testimony of an impressing confession in favour of nuclear energy. Excerpts from the speech of the Chairman of the Managing Board, Prof. Harde, are quoted.

  4. The World Heritage Centr

    Directory of Open Access Journals (Sweden)

    Ayman G. Abdel Tawab

    2014-09-01

    Full Text Available New Gourna Village, which is located inside one of the World Heritage Sites in Egypt, has never been recognized as an element contributing to the site’s Outstanding Universal Value. The recognition of the village as a contributing element is reliant on the successful assessment of its authenticity and integrity. Responding to the dramatically declining integrity of the village, the World Heritage Centre has carried out an architectural study to guide the potential conservation works in the property. The study has recommended that a group of objectives and two approaches to the conservation of the village should be adopted. One of these two approaches has been concerned with the conservation of the village according to the architect’s original intentions and principles. The previous approach can be called the principles-based approach. The main aim of this study was to examine the agreement of the World Heritage Centre’s objectives and their proposed principles-based approach to the conservation of the village with the aim to improve its chance in meeting the conditions of authenticity and integrity. The study approached the previous aim by assessing, by means of a proposed methodology; the level of significance, authenticity and integrity of the property. Based on the previous assessment, a list of conservation interventions was proposed to improve the property’s chance in meeting the conditions of authenticity and integrity. Finally, the World Heritage Centre’s recommended approaches and objectives were examined against the previous proposed conservation interventions. The findings indicated the possibility to adopt the principles-based approach to the conservation of New Gourna Village, as well as the other World Heritage Centre’s objectives, without limiting the property’s chance in meeting the conditions of authenticity and integrity. The study recommends to carry out further studies that are concerned with the identification

  5. Chinese Investment into the UK Record High

    Institute of Scientific and Technical Information of China (English)

    Alice Yang

    2010-01-01

    @@ Foreign investment from China in the UK has maintained strong growth from 59 projects(2008-09)to a new record 74 projects in2009-2010 financial year according to UK Trade & Investment Annual Review.

  6. Radiotherapy physics research in the UK: challenges and proposed solutions.

    Science.gov (United States)

    Mackay, R I; Burnet, N G; Green, S; Illidge, T M; Staffurth, J N

    2012-10-01

    In 2011, the Clinical and Translational Radiotherapy Research Working Group (CTRad) of the National Cancer Research Institute brought together UK radiotherapy physics leaders for a think tank meeting. Following a format that CTRad had previously and successfully used with clinical oncologists, 23 departments were asked to complete a pre-meeting evaluation of their radiotherapy physics research infrastructure and the strengths, weaknesses, opportunities and threats within their own centre. These departments were brought together with the CTRad Executive Group and research funders to discuss the current state of radiotherapy physics research, perceived barriers and possible solutions. In this Commentary, we summarise the submitted materials, presentations and discussions from the meeting and propose an action plan. It is clear that there are challenges in both funding and staffing of radiotherapy physics research. Programme and project funding streams sometimes struggle to cater for physics-led work, and increased representation on research funding bodies would be valuable. Career paths for academic radiotherapy physicists need to be examined and an academic training route identified within Modernising Scientific Careers; the introduction of formal job plans may allow greater protection of research time, and should be considered. Improved access to research facilities, including research linear accelerators, would enhance research activity and pass on developments to patients more quickly; research infrastructure could be benchmarked against centres in the UK and abroad. UK National Health Service departments wishing to undertake radiotherapy research, with its attendant added value for patients, need to develop a strategy with their partner higher education institution, and collaboration between departments may provide enhanced opportunities for funded research.

  7. Engaging the Somali community in the road safety agenda: a process evaluation from the London borough of Hounslow.

    Science.gov (United States)

    Christie, Nicola; Sleney, Judith; Ahmed, Fatima; Knight, Elisabeth

    2012-08-01

    In the UK the most disadvantaged in society are more likely than those more affluent to be injured or killed in a road traffic collision and therefore it is a major cause of health inequality. There is a strong link between ethnicity, deprivation and injury. Whilst national road traffic injury data does not collect ethnic origin the London accident and analysis group does in terms of broad categories such as 'white', 'black' and 'Asian'. Analysis of this data revealed the over-representation of child pedestrian casualties from a 'black' ethnic origin. This information led road safety practitioners in one London borough to map child pedestrian casualties against census data which identified the Somali community as being particularly at risk of being involved in a road traffic collision. Working with the community they sought to discuss and address road safety issues and introduced practical evidence based approaches such as child pedestrian training. The process evaluation of the project used a qualitative approach and showed that engaging with community partners and working across organisational boundaries was a useful strategy to gain an understanding of the Somali community. A bottom approach provided the community with a sense of control and involvement which appears to add value in terms of reducing the sense of powerlessness that marginalised communities often feel. In terms of evaluation, small projects like these, lend themselves to a qualitative process evaluation though it has to be accepted that the strength of this evidence may be regarded as weak. Where possible routine injury data needs to take into account ethnicity which is a known risk factor for road casualty involvement which needs to be continually monitored.

  8. The top-level global research system, 1997-99: Centres, networks and nodality

    DEFF Research Database (Denmark)

    Matthiessen, C. W.; Schwarz, Annette Winkel; Find, Søren

    2002-01-01

    of the global research centres. The data are records in the Science Catation Index 1997-99 of papers produced by authors from the 40 largest `greater' urban regions of the world as measured by research output. The network of research co-operation depends on nationality, distance and other factors. The top......-level nodes in the co-operation network of the world are London, Geneve-Lausanne and the San Francisco Bay Area. In absolute number of co-authored papers, Los Angeles, Boston and New York constitute a second level and, when observed links are related to expected links, the second level combines Amsterdam...

  9. Chernobyl accident. [Radiation monitoring in UK

    Energy Technology Data Exchange (ETDEWEB)

    Gittus, J.H.

    1986-07-01

    A brief report is given of the implications for the UK from the radioactivity released during the Chernobyl accident. Results of radio-activity monitoring around the UK are given and the additional radiation doses to the UK population are evaluated.

  10. Evaluating the effectiveness and cost-effectiveness of Dementia Care Mapping™ to enable person-centred care for people with dementia and their carers (DCM-EPIC) in care homes: study protocol for a randomised controlled trial.

    Science.gov (United States)

    Surr, Claire A; Walwyn, Rebecca E A; Lilley-Kelly, Amanda; Cicero, Robert; Meads, David; Ballard, Clive; Burton, Kayleigh; Chenoweth, Lynn; Corbett, Anne; Creese, Byron; Downs, Murna; Farrin, Amanda J; Fossey, Jane; Garrod, Lucy; Graham, Elizabeth H; Griffiths, Alys; Holloway, Ivana; Jones, Sharon; Malik, Baber; Siddiqi, Najma; Robinson, Louise; Stokes, Graham; Wallace, Daphne

    2016-06-24

    Up to 90 % of people living with dementia in care homes experience one or more behaviours that staff may describe as challenging to support (BSC). Of these agitation is the most common and difficult to manage. The presence of agitation is associated with fewer visits from relatives, poorer quality of life and social isolation. It is recommended that agitation is treated through psychosocial interventions. Dementia Care Mapping™ (DCM™) is an established, widely used observational tool and practice development cycle, for ensuring a systematic approach to providing person-centred care. There is a body of practice-based literature and experience to suggests that DCM™ is potentially effective but limited robust evidence for its effectiveness, and no examination of its cost-effectiveness, as a UK health care intervention. Therefore, a definitive randomised controlled trial (RCT) of DCM™ in the UK is urgently needed. A pragmatic, multi-centre, cluster-randomised controlled trial of Dementia Care Mapping (DCM™) plus Usual Care (UC) versus UC alone, where UC is the normal care delivered within the care home following a minimum level of dementia awareness training. The trial will take place in residential, nursing and dementia-specialist care homes across West Yorkshire, Oxfordshire and London, with residents with dementia. A random sample of 50 care homes will be selected within which a minimum of 750 residents will be registered. Care homes will be randomised in an allocation ratio of 3:2 to receive either intervention or control. Outcome measures will be obtained at 6 and 16 months following randomisation. The primary outcome is agitation as measured by the Cohen-Mansfield Agitation Inventory, at 16 months post randomisation. Key secondary outcomes are other BSC and quality of life. There will be an integral cost-effectiveness analysis and a process evaluation. The protocol was refined following a pilot of trial procedures. Changes include replacement of a

  11. The centre of the action

    CERN Multimedia

    2008-01-01

    The CERN Control Centre (CCC) has all the ingredients of an action movie control room: hundreds of screens, technicians buzzing in and out, huge floor-to-ceiling windows revealing the looming vista of a mountain range, flashing lights, microphones… This is the place where not just the LHC, but the whole of CERN’s accelerator complex and technical support is based - truly the centre of the action at CERN.

  12. Offshore wind power fundaments. Practical experience from the projects London Array and Dan Tysk; Offshore Windkraft Fundamente. Praxiserfahrung aus den Projekten London Array und DanTysk

    Energy Technology Data Exchange (ETDEWEB)

    Horn, Moritz [Bilfinger Berger Ingenieurbau GmbH, Hamburg (Germany). Ingenieurwasserbau

    2012-11-01

    Based on a collection of diagrams and images the authors of the contribution under consideration report on practical experiences resulting from the project London Array and Dan Tysk with respect to the foundations of offshore wind turbines.

  13. [Cross-validation of the first trimester screening algorithm of the FMF London on 38,700 pregnancies in Germany].

    Science.gov (United States)

    Lüthgens, K; Abele, H; Alkier, R; Hoopmann, M; Kagan, K O

    2011-08-01

    Validation of the performance of the new algorithm of the FMF London for screening for trisomy 21 using a combination of maternal age, fetal nuchal translucency (NT) and maternal serum free β-hCG and PAPP-A. Between 2002 and 2007, NT was measured prospectively in 39,004 pregnancies in the context of routinely performed first trimester screening in Germany. Individual trisomy 21 risks were calculated by a combination of NT, maternal age, free β-hCG, and PAPP-A using the FMF algorithm in force at the time of investigation. In this study we recalculated the trisomy 21 risks applying the new algorithm of the FMF UK that includes the new mixture model for the NT measurement. 38,751 singleton pregnancies could be included in the study of which 109 (0.3 %) had a trisomy 21. Only 35 % of the NT measurements of euploids were above the median and 25 % of the NT measurements were below the 5th percentile of the FMF UK. For sonographers that were qualified according to level II or III of the German DEGUM system, the median NT of fetuses with trisomy 21 was 0.9 mm above the median of the FMF UK and only 0.5 mm above the median for all other sonographers. Despite the limited performance of the NT measurement, the overall detection rate for a trisomy 21 was 90.8 % when combining the NT with maternal age, PAPP-A and free β-hCG. The overall false-positive rate for a trisomy 21 was 6.5 % at a cut-off value of 1:300. In this study we were able to show that the use of the new risk algorithm of the FMF UK leads to a trisomy 21 detection rate of about 90 % at a 5 % false-positive rate in a German collective despite a significant underestimation of the NT. © Georg Thieme Verlag KG Stuttgart · New York.

  14. Travel in holography continued: from London to Gent to Point Reyes

    Science.gov (United States)

    Casdin-Silver, Harriet

    1995-02-01

    Since Lake Forest Symposium '91, when her paper recounted her holographic work in three locations, Kiev, Ukraine; Miami Beach, U.S.A.; and Paris, France; the author has worked in the laboratories of the Royal college of Art, London, England; Rijksuniversiteit, Gent, Belgium; Third Dimension, London, England; and in Point Reyes, California, U.S.A. A discussion of these ventures follows.

  15. The electronic Discharge Letter Mobile App - The London man who went to the Tokio Olympics

    NARCIS (Netherlands)

    Lezcano, Leonardo; Ternier, Stefaan; Drachsler, Hendrik; Kalz, Marco; Specht, Marcus

    2013-01-01

    Lezcano, L., Ternier, S., Drachsler, H., Kalz, M., & Specht, M. (2013, September). The Electronic Discharge Letter Mobile App - The London man who went to the Tokio Olympics. Presentation at MEDICINE 2.0: 6th World Congress on Social Media, Mobile Apps, Internet/Web 2.0, London, England.

  16. Diversity in Adoption of Linguistic Features of London English by Chinese and Bangladeshi Adolescents

    Science.gov (United States)

    Pennington, Martha C.; Lau, Lawrence; Sachdev, Itesh

    2011-01-01

    This comparative study, conducted in multicultural London, investigates the occurrence in interviews with a researcher and in constructed same-sex peer conversations of five linguistic features characteristic of London English in the speech of two groups of British-born adolescents: ethnic Bangladeshis and ethnic Chinese of Cantonese heritage. The…

  17. Psychoanalysis of Jack London's "The Call of the Wild" and "White Fang"

    Science.gov (United States)

    Yang, Hongyan

    2015-01-01

    "The Call of the Wild" and "White Fang" both are masterpieces of Jack London. The protagonists Buck and White Fang are the incarnation of Jack himself to some extent for the two novels reveal a great deal of the writer. This essay aims at psychoanalyzing Jack London's creative process, the Oedipus complex and the confliction…

  18. Development and validation of the Dutch version of the London Handicap Scale

    NARCIS (Netherlands)

    Groothuis-Oudshoorn, C.G.M.; Chorus, A.M.J.; Verrips, G.H.W.; Detmar, S.B.

    2015-01-01

    BACKGROUND: The London Handicap Scale (LHS) was found to be a valid and reliable scale for measuring participation restrictions in adults. OBJECTIVE: This paper describes the development and assesses the construct-related validity of a Dutch version of the London Handicap Scale (DLHS). METHODS: The

  19. The electronic Discharge Letter Mobile App - The London man who went to the Tokio Olympics

    NARCIS (Netherlands)

    Lezcano, Leonardo; Ternier, Stefaan; Drachsler, Hendrik; Kalz, Marco; Specht, Marcus

    2013-01-01

    Lezcano, L., Ternier, S., Drachsler, H., Kalz, M., & Specht, M. (2013, September). The Electronic Discharge Letter Mobile App - The London man who went to the Tokio Olympics. Presentation at MEDICINE 2.0: 6th World Congress on Social Media, Mobile Apps, Internet/Web 2.0, London, England.

  20. Long-term macronutrient stoichiometry of UK ombrotrophic peatlands.

    Science.gov (United States)

    Schillereff, Daniel N; Boyle, John F; Toberman, Hannah; Adams, Jessica L; Bryant, Charlotte L; Chiverrell, Richard C; Helliwell, Rachel C; Keenan, Patrick; Lilly, Allan; Tipping, Edward

    2016-12-01

    In this paper we report new data on peat carbon (C), nitrogen (N) and phosphorus (P) concentrations and accumulation rates for 15 sites in the UK. Concentrations of C, N and P measured in peat from five ombrotrophic blanket mires, spanning 4000-10,000years to present were combined with existing nutrient data from ten Scottish ombrotrophic peat bogs to provide the first UK perspective on millennial scale macronutrient concentrations in ombrotrophic peats. Long-term average C, N and P concentrations (0-1.25m) for the UK are 54.8, 1.56 and 0.039wt%, of similar magnitude to the few published comparable sites worldwide. The uppermost peat (0-0.2m) is enriched in P and N (51.0, 1.86, and 0.070wt%) relative to the deeper peat (0.5-1.25m, 56.3, 1.39, and 0.027wt%). Long-term average (whole core) accumulation rates of C, N and P are 25.3±2.2gCm(-2)year(-)(1) (mean±SE), 0.70±0.09gNm(-2)year(-1) and 0.018±0.004gPm(-2)year(-1), again similar to values reported elsewhere in the world. The two most significant findings are: 1) that a regression model of N concentration on P concentration and mean annual precipitation, based on global meta data for surface peat samples, can explain 54% of variance in N concentration in these UK peat profiles; and 2) budget calculations for the UK peat cores yield an estimate for long-term average N-fixation of 0.8gm(-2)year(-1). Our UK results, and comparison with others sites, corroborate published estimates of N storage in northern boreal peatlands through the Holocene as ranging between 8 and 15Pg N. However, the observed correlation of N% with both mean annual precipitation and P concentration allows a potential bias in global estimates that do not take this into account. The peat sampling data set has been deposited at the NERC Data Centre (Toberman et al., 2016).

  1. Postmodern Apocalypse in White Noise and London Fields

    Directory of Open Access Journals (Sweden)

    Neda Khodadadegan

    2016-07-01

    Full Text Available Postmodern Apocalypse is considered as a strategy a writer employs to depict the dreadfulness of nuclear disaster. It is a rich way of transmitting ideas of catastrophe and fear into a more meaningful fiction about a teleological end. This study analyzes postmodern apocalypse in two selected novels, namely Don DeLillo’s White Noise (1985 and Martin Amis’s London Fields (1989. The term which refers to characters who cry their concern about the destruction of the world demonstrates a sense of apocalypse in a community of nuclear age. Both DeLillo and Amis show their fear of a nuclear explosion. The present study aims to present an apocalyptic reading of two selected texts through using in the 1980s.Elizabeth K. Rosen’s Apocalyptic Transformation: Apocalypse and the Postmodern Imagination (2008. Keywords: Postmodern Apocalyptic Literature, Apocalypse, Post-Hiroshima era

  2. Mid-nineteenth century smoke concentrations near London

    Science.gov (United States)

    Harrison, R. G.; Aplin, K. L.

    Measurements of atmospheric electricity began at Kew Observatory, London (51°28'N, 0°19'W) in 1843, with recording apparatus installed by Lord Kelvin in 1861. The measured electric potential gradient (PG) at Kew has always been influenced by smoke pollution, causing a December PG maximum and July minimum. Theory links PG variations with aerosol concentrations, and the 20th century smoke measurements made at Kew permit smoke concentrations to be retrieved from 19th century PG data. Absolute calibration of the 1862-1864 PG is achieved by considering changes in the global electric circuit, for which the geomagnetic aa-index is used as a proxy. The mean annual PG in 1863 is estimated as 363±29 V m -1, and the mean smoke concentration found is 0.17±0.05 mg m -3. Diurnal variations in smoke pollution differ between the seasons, and change in their character after the advent of motor traffic.

  3. Cost benefit analysis of 20 mph zones in London.

    Science.gov (United States)

    Steinbach, Rebecca; Cairns, John; Grundy, Chris; Edwards, Phil

    2013-06-01

    Evidence suggests that 20 mph zones are an effective intervention to reduce casualties from road traffic crashes in urban areas. This analysis compares the costs of construction of the 20 mph zone intervention in high and low casualty areas in London to the value of casualties avoided over 5 and 10 year time horizons. Probabilistic sensitivity analyses were conducted to quantify uncertainty in the results associated with model parameters. Results indicate a net present value (NPV) of £18 947 (90% credible limits -£75 252 to £82 021 2005 prices) after 5 years and £67 306 (£-29 157 to £137 890) after 10 years when 20 mph zones are implemented in areas with one or more casualty per kilometre of road. Simulations from our model suggest that the 'threshold of casualties' where NPVs become positive using a 10 year time horizon is 0.7 casualties per kilometre.

  4. Brachial plexus injury: the London experience with supraclavicular traction lesions.

    Science.gov (United States)

    Birch, Rolfe

    2009-01-01

    In this article, the author details the experiences of his hospital and other London hospitals in treating brachial plexus injury. As noted, important advances have been made in methods of diagnosis and repair. Myelography was replaced by CT scan and later by MRI. Among the topics the author explores are diagnosis (including pain, the presence or absence of the Tinel sign, and the irradiation of pins and needles) and the principles of repair. The author emphasizes that it is imperative that ruptured nerves be repaired as soon as possible, with the closed traction lesion coming, in urgency, close behind reattachment of the amputated hand or repair of a great artery and a trunk nerve in the combined lesion. Finally, the article concludes that the surgeon must be actively engaged in the whole process of rehabilitation and treatment of pain. This is part of a Point-Counterpoint discussion with Dr. David G. Kline's presentation of "A Personal Experience."

  5. Polonium-210 poisoning in London: hypochondriasis and public health.

    Science.gov (United States)

    Morgan, Oliver W; Page, Lisa; Forrester, Sarah; Maguire, Helen

    2008-01-01

    In November 2006, a Russian dissident died from radioactive Polonium-210 (210Po) poisoning in London. Providing reassuring messages during a public health incident may be ineffective for individuals with high health anxiety (hypochondriasis). Members of the public who called a 24-hour telephone helpline were offered a follow-up call by a health protection specialist for reassurance. A psychiatrist attempted to contact those callers who were unable to be reassured by the health protection specialist. Of 872 individuals contacted for reassurance, seven (0.6%) could not be reassured. The psychiatrist contacted four of these individuals. Three had a history of health-related anxiety and two attributed somatic symptoms to 210Po exposure. For individuals with hypochondriasis, reassurance during major public health incidents may be ineffective. Having a psychiatrist available was helpful in managing individuals with excessive health anxiety.

  6. Interoceptive Ability Predicts Survival on a London Trading Floor.

    Science.gov (United States)

    Kandasamy, Narayanan; Garfinkel, Sarah N; Page, Lionel; Hardy, Ben; Critchley, Hugo D; Gurnell, Mark; Coates, John M

    2016-09-19

    Interoception is the sensing of physiological signals originating inside the body, such as hunger, pain and heart rate. People with greater sensitivity to interoceptive signals, as measured by, for example, tests of heart beat detection, perform better in laboratory studies of risky decision-making. However, there has been little field work to determine if interoceptive sensitivity contributes to success in real-world, high-stakes risk taking. Here, we report on a study in which we quantified heartbeat detection skills in a group of financial traders working on a London trading floor. We found that traders are better able to perceive their own heartbeats than matched controls from the non-trading population. Moreover, the interoceptive ability of traders predicted their relative profitability, and strikingly, how long they survived in the financial markets. Our results suggest that signals from the body - the gut feelings of financial lore - contribute to success in the markets.

  7. Cosmic Rays & ULF Waves: Research in Schools Projects in London

    Science.gov (United States)

    Archer, Martin

    2017-04-01

    Research in Schools (RiS) projects offer school students opportunities to experience scientific research over prolonged periods within their school environment. Over the past two years we have piloted a RiS programme with five London schools across two research areas: the cosmic ray muons which serve as backgrounds to current neutrino experiments; and the magnetospheric ultra-low frequency waves that play a key role within space weather. From the evaluation of this pilot programme we have found that RiS can have significantly positive results on students' understanding and appreciation of science, as well as equipping them with vital skills. Teachers are also found to benefit from the projects, reconnecting them with their subject at an academic level, challenging them and aiding towards their professional development. It is important to note that supervision from current researchers was key to these outcomes. Finally, a number of recommendations on project structure, resources and workloads are presented.

  8. Do Student-Centred Learning Activities Improve Learning Outcomes on a BTEC Applied Science Course in FE?

    Science.gov (United States)

    Dear, Denise V.

    2017-01-01

    This article provides quantitative evidence on the effect on learning outcomes of contrasting teaching styles applied to a class of Level 3 final-year students on a BTEC Applied Science course within a further education college in the UK. Two topics within a unit were taught using either a student-centred or teacher-centric (instructional)…

  9. Sex differentials in caries frequencies in Medieval London.

    Science.gov (United States)

    Walter, Brittany S; DeWitte, Sharon N; Redfern, Rebecca C

    2016-03-01

    Tooth decay is one of the most common oral infections observed in skeletal assemblages. Sex differentials in caries frequency are commonly examined, with most studies finding that females tend to have a higher frequency of carious lesions (caries) compared to males. Less research has examined differences in caries between males and females with respect to age in past populations. Findings from living populations indicate that caries frequencies are higher in females, at least in part, because of the effects of estrogen and pregnancy. We are interested in the interaction of age, sex, and caries in medieval London, during a period of repeated famines, which might have exacerbated underlying biological causes of caries sex differentials. We examined caries in adults from two medieval London cemeteries dating to c. 1120-1539 AD: St. Mary Spital (n=291) and St. Mary Graces (n=80) to test the hypothesis that males and females have different caries frequencies irrespective of age. The association between maxillary molar caries and sex was tested using hierarchical log-linear analysis to control for the effects of age on caries frequencies. The results indicate a higher frequency of maxillary molar caries in females (P<0.00), and that the age distribution of caries differs between the sexes (P=0.01), with a consistent increase in frequency with age for females until late adulthood, but not males. The difference in caries frequencies is not explained by differences in the age distributions of the sexes. Differences in the age patterns of caries for males and females could be the result of biological factors that present during reproductive age, differences in diet, or differential access to resources during famine. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Assessment of the noise exposure of call centre operators.

    Science.gov (United States)

    Patel, Jacqueline A; Broughton, Keith

    2002-11-01

    Call centres now play a major role in the daily operations of financial, technology and utility companies, as well as public bodies. It is predicted that 2002 will see 2.3% of the total British workforce employed in call centres. However, local authority enforcement officers, unions, voluntary organizations, employers and employees have all expressed concern that there are hazards to health and safety unique to this new and developing industry. One of the potential hazards reported in the press is hearing damage from using headsets. In a Health & Safety Executive funded project, the noise exposure of 150 call centre operators was evaluated, in call centres which included financial services, home shopping and telecommunications services. The results show that the daily personal noise exposure of these call centre operators is unlikely to exceed the 85 dB(A) action level defined in the Noise at Work Regulations 1989. The risk of hearing damage is therefore extremely low. Exposure to higher noise levels is possible, for example from fax tones, holding tones and high pitched tones from mobile phones. However, the duration of these events is likely to be short and they are therefore unlikely to have a significant effect on the operators' overall noise exposure. A practical method of limiting exposure to unexpected high noises from headsets is to ensure that the headsets incorporate acoustic shock protection that meets the requirements of the Department of Trade and Industry specification 85/013. In the UK, this limiter ensures any noise above 118 dB is not transmitted through the headset. Operators should receive regular training on the headset and telephone equipment they are using. This training should include correct use of the headset and the volume control facilities, and advice on how and when to clean and maintain the headsets.

  11. UK coal mining engineering capability

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-03-01

    The document outlines the current position of underground coal mining in the UK and identifies the key suppliers of equipment and services, in the following sections: longwall face machinery; roadway drivage; seismic exploration; ventilation; methane drainage; underground transport; electrical and control systems; underground safety; research and development; consultancy services; coal associations. A directory of 43 companies organizations and academic institutions is included. 13 figs., 1 tab.

  12. Online Shopping In The UK

    OpenAIRE

    Ramachandran, K.K.; K. K. Karthick; M. Saravana Kumar

    2011-01-01

    This paper will contribute to current academic literature in the area of online retailing and consumer behaviour. Our research outlines a survey conducted with respondents from the UK to ascertain their attitudes to grocery shopping both off and online. The findings indicate that, whilst the vast majority of our sample has experience of online shopping, few actively engage in online grocery shopping. Some of the reasons for this are highlighted and the key issues relate to consumer trust and ...

  13. BrisSynBio: a BBSRC/EPSRC-funded Synthetic Biology Research Centre.

    Science.gov (United States)

    Sedgley, Kathleen R; Race, Paul R; Woolfson, Derek N

    2016-06-15

    BrisSynBio is the Bristol-based Biotechnology and Biological Sciences Research Council (BBSRC)/Engineering and Physical Sciences Research Council (EPSRC)-funded Synthetic Biology Research Centre. It is one of six such Centres in the U.K. BrisSynBio's emphasis is on rational and predictive bimolecular modelling, design and engineering in the context of synthetic biology. It trains the next generation of synthetic biologists in these approaches, to facilitate translation of fundamental synthetic biology research to industry and the clinic, and to do this within an innovative and responsible research framework. © 2016 The Author(s).

  14. Findings of, and reflections on, the Gender, Lifelong Learning and Social Class (GLAS project. A UK partnership based perspective.

    Directory of Open Access Journals (Sweden)

    Sue Betts

    2014-06-01

    Full Text Available This paper describes the main findings of GLAS, a two-year, EC co-funded project to address potential barriers to lifelong learning. In considering the genesis of the project, its structure and partnership, we will discuss findings from the perspective of UK partners, Linking London. We will show that tackling complex issues of social inclusion requires the creative use of processes and strategies which already exist within higher education, and conclude by making recommendations for future research and action.

  15. Worldwide open access: UK leadership?

    Directory of Open Access Journals (Sweden)

    Stevan Harnad

    2013-03-01

    Full Text Available The web is destined to become humankind's cognitive commons, where digital knowledge is jointly created and freely shared. The UK has been a leader in the global movement toward open access (OA to research but recently its leadership has been derailed by the joint influence of the publishing industry lobby from without and well-intentioned but premature and unhelpful over-reaching from within the OA movement itself. The result has been the extremely counterproductive ‘Finch Report’ followed by a new draft of the Research Councils UK (RCUK OA mandate, downgrading the role of cost-free OA self-archiving of research publications (‘green OA’ in favor of paying subscription publishers over and above subscriptions, out of scarce research funds, in exchange for making single articles OA (‘hybrid gold OA’. The motivation of the new policy is to reform publication and to gain certain re-use rights (CC-BY, but the likely effect would be researcher resistance, very little OA and a waste of research funds. There is still time to fix the RCUK mandate and restore the UK's leadership by taking a few very specific steps to clarify and strengthen the green component by adding a mechanism for monitoring and verifying compliance, with consequences for non-compliance, along lines also being adopted in the EC and the US.

  16. Equine uveitis: a UK perspective.

    Science.gov (United States)

    Lowe, R C

    2010-03-01

    Uveitis in the equine population of the UK does not appear to be as prevalent or disastrous as seen across regions of Europe and the USA. Some cases perceived to be recurrent uveitis may be poorly resolved single episodes of uveitis and care should be taken not to make the diagnosis of recurrence without ensuring effective control of the initial episode. Leptospira spp. appear to play only a minor role ERU in the UK which is probably the main reason for the prevalence of the disease being much lower compared to the USA and mainland Europe. Actual data are relatively few on the ground as far as disease surveillance in concerned. This has 2 implications. Firstly unless we are able to effectively monitor the levels of uveitic disease, it will be difficult to pick up early changes in the trend which may allow quicker intervention. Secondly, it is difficult to secure funding for further research if the prevalence of the problem is poorly defined. This may leave the UK equine population at risk should the disease profile suddenly alter for the worse.

  17. Nutritional Knowledge of UK Coaches

    Directory of Open Access Journals (Sweden)

    Emma Cockburn

    2014-04-01

    Full Text Available Athletes obtain nutritional information from their coaches, yet their competency in this area is lacking. Currently, no research exists in the UK which has a different coach education system to many other countries. Therefore, the aim of this study was to evaluate the sports nutrition knowledge of UK coaching certificate (UKCC level 2 and 3, hockey and netball qualified coaches. All coaches (n = 163 completed a sports nutrition questionnaire to identify: (a if they provided nutritional advice; (b their level of sport nutrition knowledge; and (c factors that may have contributed to their level of knowledge. Over half the coaches provided advice to their athletes (n = 93, 57.1%, even though they were not competent to do so. Coaches responded correctly to 60.3 ± 10.5% of all knowledge questions with no differences between those providing advice and those who did not (p > 0.05. Those coaches who had undertaken formal nutrition training achieved higher scores than those who had not (p < 0.05. In conclusion, UK sports coaches would benefit from continued professional development in sports nutrition to enhance their coaching practice.

  18. Liver transplantation in the UK

    Institute of Scientific and Technical Information of China (English)

    SR Bramhall; E Minford; B Gunson; JAC Buckels

    2001-01-01

    Introduction: This paper provides a review of the practice of liver transplantation with the main emphasis on UK practice and indications for transplantation.``Referral and Assessment: This section reviews the process of referral and assessment of patients with liver disease with reference to UK practice.``Donor Organs: The practice of brainstem death and cadaveric organ donation is peculiar to individual countries and rates of donation and potential areas of improvement are addressed.``Operative Technique: The technical innovations that have led to liver transplantation becoming a semi-elective procedure are reviewed. Specific emphasis is made to the role of liver reduction and splitting and living related liver transplantation and how this impacts on UK practice are reviewed. The complications of liver transplantation are also reviewed with reference to our own unit.``Imrnunosuppression: The evolution of immunosuppression and its impact on liver transplantation are reviewed with some reference to future protocols.Retransplantation: The role of retransplantation is reviewed.``Outcome and Survival: The results of liver transplantation are reviewed with specific emphasis on our own experience.``Future: The future of liver transplantation is addressed.``

  19. UK Defence Acquisition Process for NEC: Transaction Governance within an Integrated Project Team

    Science.gov (United States)

    2009-04-22

    a PhD candidate in his second year at MBS, researching UK defence acquisition applying a transaction cost approach. Ermias Kebede Centre for...Williamson’s (1975,1985) work on transaction cost economics (TCE) as a model of understanding managers’ behaviour in an economic environment...modernisation programme is a gradual change in the structure of the defence sector. In the governance level section, we use a transaction cost approach

  20. Neck and Back Pain in Undergraduate Dental Students at a UK Dental School

    OpenAIRE

    2016-01-01

    Objective Limited data exist on musculoskeletal problems within dental students: we aimed to determine the prevalence of these disorders. Design Single centre cross-sectional study Setting A UK Dental School 2015. Subjects (materials) and methods Students completed a modified Nordic pain questionnaire. Main outcome measures Self-reported frequency and severity of pain, fitness and coping strategies. Results 63% of 390 respondents were female and 75% aged under 23. Seventy-nine percent experie...

  1. The inevitable drift to triple therapy in COPD: an analysis of prescribing pathways in the UK

    OpenAIRE

    Brusselle G; Price D; Gruffydd-Jones K; Miravitlles M; Keininger DL; Stewart R; Baldwin M; Jones RC

    2015-01-01

    Guy Brusselle,1–3 David Price,4,5 Kevin Gruffydd-Jones,6 Marc Miravitlles,7 Dorothy L Keininger,8 Rebecca Stewart,5 Michael Baldwin,9 Rupert C Jones101Department of Respiratory Medicine, University Hospital Ghent, Ghent, Belgium; 2Department of Epidemiology, 3Department of Respiratory Medicine, Erasmus Medical Center, Rotterdam, Netherlands; 4Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK; 5Research in Real Life (RiRL), Singapore; 6Box Surgery, Wiltsh...

  2. The ideal Atomic Centre; Le Centre Atomique ideal

    Energy Technology Data Exchange (ETDEWEB)

    Mas, R. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1965-07-01

    The author presents considerations which should prove to be of interest to all those who have to design, to construct and to operate a nuclear research centre. A large number of the ideas presented can also be applied to non-nuclear scientific research centres. In his report the author reviews: various problems with which the constructor is faced: ground-plan, infrastructure, buildings and the large units of scientific equipment in the centre, and those problems facing the director: maintenance, production, supplies, security. The author stresses the relationship which ought to exist between the research workers and the management. With this aim in view he proposes the creation of National School for Administration in Research which would train administrative executives for public or private organisations; they would be specialised in the fields of fundamental or applied research. (author) [French] L'auteur propose une base de reflexions a tous ceux qui doivent concevoir, realiser et faire vivre un Centre d'Etudes Nucleaires. Un grand nombre des idees exprimees peut d'ailleurs s'appliquer a un Centre d'Etudes Scientifiques non nucleaires. Dans son ouvrage, l'auteur passe en revue les differents problemes qui se posent au constructeur: plan, masse, infrastructure, batiments et grands appareils du Centre, et ceux qu'a a resoudre le directeur: entretien, fabrication, approvisionnements, securite. L'auteur insiste sur l'aspect des rapports qui doivent exister entre les chercheurs et ceux qui les administrent. Il propose a cette fin la creation d'une Ecole Nationale d'Administration de la Recherche qui formerait des cadres administratifs pour les organismes publics ou prives, specialises dans la Recherche fondamentale ou appliquee. (auteur)

  3. Rhetoric, Reality, and Rationalization: A Study of the Masking Function of Rhetoric in the London Theosophical Movement.

    Science.gov (United States)

    Clark, Thomas D.

    1978-01-01

    Examines the history of the "Blavatsky" phase of the London Theosophical movement. Focuses on the disparity between the public rhetoric of the Theosophical Society's leadership and the deeper motivations which inspired many Londoners to join the movement. (JMF)

  4. Engaging nurses in genetics: the strategic approach of the NHS National Genetics Education and Development Centre.

    Science.gov (United States)

    Kirk, Maggie; Tonkin, Emma; Burke, Sarah

    2008-04-01

    The UK government announced the establishment of an NHS National Genetics Education and Development Centre in its Genetics White Paper. The Centre aims to lead and coordinate developments to enhance genetics literacy of health professionals. The nursing program takes a strategic approach based on Ajzen's Theory of Planned Behavior, using the UK nursing genetics competences as the platform for development. The program team uses innovative approaches to raise awareness of the relevance of genetics, working collaboratively with policy stakeholders, as key agents of change in promoting competence. Providing practical help in preparing learning and teaching resources lends further encouragement. Evaluation of the program is dependent on gathering baseline data, and the program has been informed by an education needs analysis. The challenges faced are substantial and necessitate international collaboration where expertise and resources can be shared to produce a global system of influence to facilitate the engagement of non-genetic nurses.

  5. The average body surface area of adult cancer patients in the UK: a multicentre retrospective study.

    Directory of Open Access Journals (Sweden)

    Joseph J Sacco

    Full Text Available The majority of chemotherapy drugs are dosed based on body surface area (BSA. No standard BSA values for patients being treated in the United Kingdom are available on which to base dose and cost calculations. We therefore retrospectively assessed the BSA of patients receiving chemotherapy treatment at three oncology centres in the UK between 1(st January 2005 and 31(st December 2005.A total of 3613 patients receiving chemotherapy for head and neck, ovarian, lung, upper GI/pancreas, breast or colorectal cancers were included. The overall mean BSA was 1.79 m(2 (95% CI 1.78-1.80 with a mean BSA for men of 1.91 m(2 (1.90-1.92 and 1.71 m(2 (1.70-1.72 for women. Results were consistent across the three centres. No significant differences were noted between treatment in the adjuvant or palliative setting in patients with breast or colorectal cancer. However, statistically significant, albeit small, differences were detected between some tumour groups.In view of the consistency of results between three geographically distinct UK cancer centres, we believe the results of this study may be generalised and used in future costings and budgeting for new chemotherapy agents in the UK.

  6. Radiotherapy dosimetry audit: three decades of improving standards and accuracy in UK clinical practice and trials.

    Science.gov (United States)

    Clark, Catharine H; Aird, Edwin G A; Bolton, Steve; Miles, Elizabeth A; Nisbet, Andrew; Snaith, Julia A D; Thomas, Russell A S; Venables, Karen; Thwaites, David I

    2015-01-01

    Dosimetry audit plays an important role in the development and safety of radiotherapy. National and large scale audits are able to set, maintain and improve standards, as well as having the potential to identify issues which may cause harm to patients. They can support implementation of complex techniques and can facilitate awareness and understanding of any issues which may exist by benchmarking centres with similar equipment. This review examines the development of dosimetry audit in the UK over the past 30 years, including the involvement of the UK in international audits. A summary of audit results is given, with an overview of methodologies employed and lessons learnt. Recent and forthcoming more complex audits are considered, with a focus on future needs including the arrival of proton therapy in the UK and other advanced techniques such as four-dimensional radiotherapy delivery and verification, stereotactic radiotherapy and MR linear accelerators. The work of the main quality assurance and auditing bodies is discussed, including how they are working together to streamline audit and to ensure that all radiotherapy centres are involved. Undertaking regular external audit motivates centres to modernize and develop techniques and provides assurance, not only that radiotherapy is planned and delivered accurately but also that the patient dose delivered is as prescribed.

  7. Sustaining International CBRN Centers of Excellence with a Focus on Nuclear Security and Safeguards: Initial Scoping Session London, 23-24 September 2013 SUMMARY REPORT

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Roger G.; Frazar, Sarah L.

    2013-12-12

    This report provides a summary-level description of the key information, observations, ideas, and recommendations expressed during the subject meeting. The report is organized to correspond to the meeting agenda provided in Appendix 1 and includes references to several of the participants listed in Appendix 2 .The meeting venue was Lloyd’s Register in the City of London. Lloyd’s Register graciously accommodated the request of The Pacific Northwest Laboratory (PNNL) with whom it works on various safeguards activities commissioned by NNSA. PNNL and NNSA also shared the goal of the meeting/study with the United Kingdom (UK) Foreign and Commonwealth Office (FCO) and the Department of Energy and Climate Change with whom they coordinated the participant list.

  8. The sero-epidemiology of human papillomavirus among Caucasian transplant recipients in the UK

    Directory of Open Access Journals (Sweden)

    Newton Robert

    2009-09-01

    Full Text Available Abstract Background Despite intensive study of high-risk mucosal human papillomaviruses (HPV, little is known of the epidemiology of cutaneous HPV. As part of a study of cutaneous squamous cell carcinoma and HPV among organ transplant recipients (OTR from London and Oxford, we investigated the seroprevalence and risk factors for 34 HPV types (detected using Luminex technology among 425 Caucasian OTR without skin cancer. Results Overall, 86% of participants were seropositive to at least one HPV: 41% to mucosal alpha types, 33% to cutaneous alpha types, 57% to alpha types, 56% to beta, 47% to gamma types and 45% to other types (nu, mu, HPV101 and 103. In both centres, the most common types were HPV6 (33% and 26% for London and Oxford respectively, HPV8 (24% and 18%, HPV15 (26% and 29%, HPV17 (25% and 21%, HPV38 (23% and 21%, HPV49 (19% and 21%, HPV4 (27% and 23%, HPV65 (30% and 25%, HPV95 (22% and 20%, HPV1 (33% and 24% and HPV63 (28% and 17%. The seroprevalence of 8 HPV types differed significantly (P Conclusion Findings for mucosal HPV types were in line with results from previous studies. We observed differences in HPV seroprevalence between organ transplant recipients from two geographically close centres but no clear risk factor was found associated with cutaneous HPV seropositivity among organ transplant recipients. These findings have implications for interpretation of future seroepidemiology studies addressing the association between HPV and cutaneous SCC in OTR populations.

  9. The emergence of urban centres

    DEFF Research Database (Denmark)

    Lazaro, Evelyn; Agergaard, Jytte; Larsen, Marianne Nylandsted

    In this paper we aim at understanding how social and spatial transformation of dynamic rural regions is driving spatial concentration and urbanization. We are particularly concerned with the processes of spatial change, verbalized as the emergence of urban centres in rural areas. Emerging Urban...... Centres (EUCs) are characterized by rapid population growth related to continuous and diverse flows of migrants from rural hinterlands and more detached rural locations. Many of these centres are also characterized by economic dynamics related to agricultural sector activities that have been stimulated...... by Tanzanian market liberalizations and its long term effects on private enterprise. The paper is based on a study of four EUCs in Tanzania (Ilula, Igowole, Madizini and Kibaigwa) and seeks to answer three research questions: 1) What economic and spatial trends, including national policies, have formed...

  10. Construction of the Wigner Data Centre

    CERN Multimedia

    2013-01-01

    A remote extension of the CERN data centre has recently been inaugurated. Hosted at the Wigner Research Centre for Physics in Hungary, it provides extra computing power required to cover CERN’s needs. This video presents the construction of the Wigner Data Centre from initial demolishing work through to its completion and details the major technical characteristics of the Data Centre.

  11. Construction of the Wigner Data Centre

    CERN Document Server

    2013-01-01

    A remote extension of the CERN data centre has recently been inaugurated. Hosted at the Wigner Research Centre for Physics in Hungary, it provides extra computing power required to cover CERN’s needs. This video presents the construction of the Wigner Data Centre from initial demolishing work through to its completion and details the major technical characteristics of the Data Centre.

  12. Scheduling participants of Assessment Centres

    DEFF Research Database (Denmark)

    Lysgaard, Jens; Løber, Janni

      Assessment Centres are used as a tool for psychologists and coaches to observe a number of dimensions in a person's behaviour and test his/her potential within a number of chosen focus areas. This is done in an intense course, with a number of different exercises which expose each participant...... Centres usually last two days and involve 3-6 psychologists or trained coaches as assessors. An entire course is composed of a number of rounds, with each round having its individual duration. In each round, the participants are divided into a number of groups with prespecifed pairing of group sizes...

  13. 'Ye Olde Hot Aire': reporting on human contributions to climate change in the UK tabloid press

    Science.gov (United States)

    Boykoff, Maxwell T.; Mansfield, Maria

    2008-04-01

    This letter explores daily print media coverage of climate change in four United Kingdom (UK) tabloid newspapers: The Sun (and News of the World), Daily Mail (and Mail on Sunday), the Daily Express (and Sunday Express), and the Mirror (and Sunday Mirror). Through examinations of content in articles over the last seven years (2000 2006), triangulated with semi-structured interviews of journalists and editors, the study finds that UK tabloid coverage significantly diverged from the scientific consensus that humans contribute to climate change. Moreover, there was no consistent increase in the percentage of accurate coverage throughout the period of analysis and across all tabloid newspapers, and these findings are not consistent with recent trends documented in United States and UK 'prestige press' or broadsheet newspaper reporting. Findings from interviews indicate that inaccurate reporting may be linked to the lack of specialist journalists in the tabloid press. This study therefore contributes to wider discussions of socio-economic inequality, media and the environment. Looking to newspapers that are consumed by typically working class readership, this article contributes to ongoing investigations related to what media representations mean for ongoing science policy interactions as well as potentialities for public engagement. Headline from a Daily Mail article analyzed during this study, which claimed to 'debunk the myth of global warming' (Hanlon 2003 Ye olde hot aire Daily Mail London (8 April) p 17).

  14. Producing the BEANs needed for person-centred healthcare decision making requires translating the wisdom of the clinical crowd

    DEFF Research Database (Denmark)

    Kaltoft, Mette Kjer; Eiring, Øystein; Nielsen, Jesper Bo

    Producing the BEANs needed for person-centred healthcare decision making requires translating the wisdom of the clinical crowd Mette Kjer Kaltoft, University of Southern Denmark Øystein Eiring, Norwegian Knowledge Centre for the Health Services Jesper Bo Nielsen, University of Southern Denmark...... Glenn Salkeld, University of Sydney School of Public Health Jack Dowie, London School of Hygiene and Tropical Medicine (presenting) Abstract (500) Person-centred care is the increasingly avowed aim of health services and professionals. To be meaningful such care requires a shared decision making process...... in which an individual's preferences over the multiple criteria that matter to them are synthesised with the Best Estimate Available Now (at the point of decision) for how well each of the available options will perform on each criterion. Conventional evidence-based approaches can meet the latter...

  15. Radical observations during the Clean air for London project

    Science.gov (United States)

    Whalley, L. K.; Stone, D.; Clancy, N.; Lee, J. D.; Laufs, S.; Kleffmann, J.; Heard, D. E.

    2012-12-01

    With greater than 50 % of the global population residing in urban conurbations, poor urban air quality has a demonstrable effect on human health. OH and HO2 radicals, (collectively termed HOx) together with RO2 radicals, mediate virtually all of the oxidative chemistry in the atmosphere, being responsible for the transformation of primary emissions into secondary pollutants such as NO2, O3 and particulates. Understanding the chemistry of free-radicals in the atmosphere is essential in improving predictions of the lifetimes of pollutants and spatial scales of their transport within urban areas. Results from earlier field campaigns in urban and polluted regions have demonstrated the significance of HONO photolysis and alkene ozonolysis in the production of HOx radicals. In many cases, however, measurements of HONO have not been made, reducing the ability to evaluate model successes for OH in these environments. Here we present measurements of OH, HO2, RO2 and OH reactivity taken during the wintertime (January - February, 2012) and summertime (July - August, 2012) as part of the Clean air for London (ClearfLo) project in London. RO2 was detected using a newly developed flow-reactor laser-induced fluorescence technique which is able to discriminate between HO2 and organic peroxy radicals [1]. Low concentrations of radicals were observed during the wintertime, midday [OH], [HO2] and [RO2] were ~ 0.04, 0.8 and 1.5 pptv respectively, comparable to observations of radicals at other urban locations in winter [2,3,4], and which displayed a negative correlation with NO concentrations. OH reactivity was high and largely tracked the diurnal profiles of NOx and CO, with the highest reactivity ~100 s-1 observed during the morning rush hour. Analysis of factors controlling OH concentrations during the wintertime suggests that the formation of OH from the photolysis of O3 and subsequent reaction of O(1D) with H2O is a minor contribution both under high and low NOx conditions owing

  16. History magazines in the UK

    OpenAIRE

    Haydn, Terry

    2013-01-01

    The paper explores the phenomenon of popular history magazines as a facet of public history. The UK has seen a substantial increase in the number of popular history magazines available to the public, with some magazines reaching high levels of circulation. The paper looks at the range of magazines available – from ‘heritage’ and ‘family’ history, to special interest magazines, and more ‘serious’ and scholarly history magazines. What is it that makes history magazines sell, and what influence ...

  17. LDE centres: sprint or marathon?

    NARCIS (Netherlands)

    Bonger, S.; Van Rein, E.

    2015-01-01

    The aim of the Strategic Leiden-Delft-Erasmus Alliance, established by the three universities in 2012, was to improve research and education and competitiveness. Projects are intended to develop from the ground up, which led to the establishment of eight joint centres in 2013. A quick look around re

  18. The UK National Infrastructure Plan 2010

    OpenAIRE

    Stewart, James

    2010-01-01

    The challenges of infrastructure finance need to be considered in the context of long-term infrastructure planning. This article outlines the UK's new integrated approach to infrastructure planning to meet large investment needs against the backdrop of fiscal consolidation. The UK National Infrastructure Plan for the first time sets our a broad, integrated, corss-sectoral vision and plan for the substantial infrastructure investment required to underpin the UK's economic growth. This plan wil...

  19. Making progress: UKCIP & adaptation in the UK

    OpenAIRE

    2011-01-01

    The UK Climate Impacts Programme (UKCIP) was established by the UK Government in 1997, who awarded the contract for co-ordinating research into the likely impacts of climate change in the UK to the Environmental Change Institute at the University of Oxford. It was originally established to provide decision-makers with information on climate change impacts, and did not have a remit to consider adaptation to climate change.

  20. Cultural Background Variables in Dance Talent Development: Findings from the UK Centres for Advanced Training

    Science.gov (United States)

    Sanchez, Erin N.; Aujla, Imogen J.; Nordin-Bates, Sanna

    2013-01-01

    This study is a qualitative enquiry into cultural background variables--social support, values, race/ethnicity and economic means--in the process of dance talent development. Seven urban dance students in pre-vocational training, aged 15-19, participated in semi-structured interviews. Interviews were inductively analysed using QSR International…

  1. Does Early Decompressive Craniectomy Improve Outcome? Experience from an Active UK Recruiter Centre

    Directory of Open Access Journals (Sweden)

    E. García Vicente

    2013-01-01

    Full Text Available Introduction. The results of the recent DECRA study suggest that although craniectomy decreases ICP and ICU length of stay, it is also associated with worst outcomes. Our experience, illustrated by these two striking cases, supports that early decompressive craniectomy may significantly improve the outcome in selected patients. Case Reports. The first patient, a 20-year-old man who suffered severe brain contusion and subarachnoid haemorrhage after a fall downstairs, with refractory ICP of 35 mmHg, despite maximal medical therapy, eventually underwent decompressive craniectomy. After 18 days in intensive care, he was discharged for rehabilitation. The second patient, a 23-year-old man was found at the scene of a road accident with a GCS of 3 and fixed, dilated pupils who underwent extensive unilateral decompressive craniectomy for refractory intracranial hypertension. After three weeks of cooling, paralysis, and neuroprotection, he eventually left ICU for rehabilitation. Outcomes. Four months after leaving ICU, the first patient abseiled 40 m down the main building of St. Mary’s Hospital to raise money for the Trauma Unit. He has returned to part-time work. The second patient, was decannulated less than a month later and made a full cognitive recovery. A year later, with a titanium skull prosthesis, he is back to part-time work and to playing football. Conclusions. Despite the conclusions of the DECRA study, our experience of the use of early decompressive craniectomy has been associated with outstanding outcomes. We are currently actively recruiting patients into the RESCUEicp trial and have high hopes that it will clarify the role of the decompressive craniectomy in traumatic brain injury and whether it effectively improves outcomes.

  2. Characteristics of Talented Dancers and Age Group Differences: Findings from the UK Centres for Advanced Training

    Science.gov (United States)

    Walker, Imogen J.; Nordin-Bates, Sanna M.; Redding, Emma

    2011-01-01

    This study investigated differences in the characteristics of talented dancers in relation to age. Physical (handgrip muscular strength, leg muscular power, hamstring flexibility and external hip rotation), psychological (passion, self-esteem and anxiety) and social (the motivational climate) characteristics were assessed in 334 students enrolled…

  3. Endoscopic thoracic sympathectomy for primary hyperhidrosis: a 16-year follow up in a single UK centre.

    Science.gov (United States)

    Askari, Alan; Kordzadeh, Ali; Lee, Gui Han; Harvey, Michael

    2013-06-01

    Since the introduction of Endoscopic Thoracic Sympathectomy ( ETS ) by Kux in 1951, the procedure has been performed for treatment of primary hyperhidrosis (PH) of the upper limb. Despite its initial success and minimally invasive nature, the long-term results are yet to be established. The aim of this study is to evaluate the outcome of patients after ETS with particular emphasis on patient satisfaction and its effectiveness over a 16-year period. A patient survey of fifty-one (n = 51) patients who had ETS for PH of palms from 1995 to 2011 was conducted. The data on age, sex, site of the PH, family history, trigger, hospital stay, relief from symptoms, complications, refractory sweating and overall satisfaction with the procedure was analysed with SAS software version 9.1.3. The mean follow-up was 77 months (range, 6-189 months) with equal gender distribution (n = 24 males Vs n = 27 females) and mean age of 19 (range, 13-64 years). The hereditary prevalence was 55%. Forty-six patients (90.2%) reported an immediate (≤24 h) and four patients (7.8%) reported a delay (>24 h) in relief of symptoms. To the best of our knowledge this is longest duration of follow-up reported in the literature. Copyright © 2012 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.

  4. Outcome of gastroplasty and gastric bypass in a single centre in the UK

    Directory of Open Access Journals (Sweden)

    Sintler M

    2009-09-01

    Full Text Available Abstract Background Morbid obesity is defined as BMI>40 kg/m2. It affects 124,000 men and 412,000 women in England and Wales (NICE, July 2002. According to NICE guidelines, Bariatric surgery is indicated if the treatments for obesity such as exercise, diet and drugs fail. Procedures include laparoscopic gastric banding (LGB, vertical banded gastroplasty (VBG, and Gastric Bypass (GB. Aims The aim of this audit was to determine if NICE guidelines on the use of Bariatric surgery in the Manor Hospital, Walsall was being adhered to. Secondary aims were also to establish if Bariatric surgery is achieving its goal in the long-term and if weight reduction is being maintained in this group of patients. Methods A retrospective cohort study was carried out on patients who underwent Bariatric surgery between 1990 and 2004. Retrieved records were scrutinised and the following parameters were collated: pre-operative morbidities, intra and post-operative complication rates and weight reduction on follow-up. Results 129 patients were operated on in the 14 year period. For VBG, 40 out of 105 patients had weight gain by the 5th follow-up visit. This compared with 5 out of 18 patients after the same timescale for the GB group and 1 out of 6 in the LGB group. The most common post-operative complication was stenosis (28% of VBG group. Conclusion Bariatric surgery is relatively safe as an intervention for morbid obesity. Weight loss however is not maintained in the long term. VBG and LGB are short term interventions. Further research is required to look into the merits of gastric bypass surgery.

  5. Multidisciplinary predictors of adherence to contemporary dance training: findings from the UK Centres for Advanced Training.

    Science.gov (United States)

    Aujla, Imogen J; Nordin-Bates, Sanna M; Redding, Emma

    2015-01-01

    Little is known about the predictors of adherence in a dance context. The aim of this study was to investigate adherence to a dance talent programme using a multidisciplinary set of variables representing psychological correlates of adherence, maturation and physical factors relating to dance talent. Psychological (passion, motivational climate perceptions, eating attitudes), physical competence (vertical jump height, handgrip strength, hamstring flexibility, external hip rotation, aerobic fitness), and maturation-related (age of menarche) variables were gathered from female students enrolled on a dance talent programme. Participation behaviour (adherence/dropout) was collected from the talent programme's records approximately two years later. Logistic regression analysis of 287 participants revealed that greater levels of harmonious passion predicted greater likelihood of adherence to the programme, and greater ego-involving motivational climate perceptions predicted less likelihood of adherence. Neither measures of physical competence nor maturation distinguished adhering from dropout participants. Overall, the results of this study indicate that psychological factors are more important than physical competence and maturation in the participation behaviour of young talented dancers.

  6. Theorizing Surveillance in the UK Crime Control Field

    Directory of Open Access Journals (Sweden)

    Michael McCahill

    2015-09-01

    Full Text Available Drawing upon the work of Pierre Bourdieu and Loic Wacquant, this paper argues that the demise of the Keynesian Welfare State (KWS and the rise of neo-liberal economic policies in the UK has placed new surveillance technologies at the centre of a reconfigured “crime control field” (Garland, 2001 designed to control the problem populations created by neo-liberal economic policies (Wacquant, 2009a. The paper also suggests that field theory could be usefully deployed in future research to explore how wider global trends or social forces, such as neo-liberalism or bio-power, are refracted through the crime control field in different national jurisdictions. We conclude by showing how this approach provides a bridge between society-wide analysis and micro-sociology by exploring how the operation of new surveillance technologies is mediated by the “habitus” of surveillance agents working in the crime control field and contested by surveillance subjects.

  7. Theorizing Surveillance in the UK Crime Control Field

    Directory of Open Access Journals (Sweden)

    Michael McCahill

    2015-09-01

    Full Text Available Drawing upon the work of Pierre Bourdieu and Loic Wacquant, this paper argues that the demise of the Keynesian Welfare State (KWS and the rise of neo-liberal economic policies in the UK has placed new surveillance technologies at the centre of a reconfigured “crime control field” (Garland, 2001 designed to control the problem populations created by neo-liberal economic policies (Wacquant, 2009a. The paper also suggests that field theory could be usefully deployed in future research to explore how wider global trends or social forces, such as neo-liberalism or bio-power, are refracted through the crime control field in different national jurisdictions. We conclude by showing how this approach provides a bridge between society-wide analysis and micro-sociology by exploring how the operation of new surveillance technologies is mediated by the “habitus” of surveillance agents working in the crime control field and contested by surveillance subjects.

  8. Imported dengue fever in East London: a 6-year retrospective observational study.

    Science.gov (United States)

    Riddell, Anna; Babiker, Zahir Osman Eltahir

    2017-05-01

    Dengue fever (DF) is a frequently imported arthropod-borne infection in the United Kingdom but its broad range of clinical presentations makes it potentially unrecognized by clinicians. We conducted a 6-year retrospective case note review of laboratory confirmed DF patients in East London in the period from 1 January 2010 through 31 December 2015. Epidemiological, clinical and laboratory features of imported DF were described. Risk factors associated with viraemic DF presentations were assessed. Forty-four patients (4 from primary care clinics and 40 from three acute hospitals) were confirmed to have DF through RNA and/or IgM detection. In total, 86.4% (38/44) had primary infection compared to 13.6% (6/44) with secondary infection. Viraemic DF presentations accounted for 59.1% (26/44) of cases. The median age was 34 years (IQR 25-43). Most patients were males (68.2%, 30/44) and of non-white ethnicity (81.8%, 36/44). South Asia was the most frequent travel destination (52.3%, 23/44) followed by Southeast Asia (20.5%, 9/44). July-September was the peak season of presentation (43.2%, 19/44). The median interval between arrival in the UK and laboratory testing was 7 days (IQR 4-13). Arriving from abroad ≤ 7 days before molecular testing (age-adjusted odds ratios [OR] 16.98, 95% CI 2.43-118.75, P  =   0.004) and travel to South or Southeast Asia regions (age-adjusted OR 4.41, 95% CI 1.07-18.21, P  =   0.040) were associated with detectable viraemia at presentation. Only one DF patient met the WHO severity criteria. HIV serostatus was determined in 61.4% (27/44) of cases. Clinicians need to improve DF recognition as well as rates of HIV testing in tropical travellers. Region of travel and time since arrival from DF endemic settings may help clinicians optimize requests for molecular testing. Further research on the clinical and public health aspects of imported DF is needed.

  9. Pub Culture in the U.K.

    Institute of Scientific and Technical Information of China (English)

    孙鑫

    2015-01-01

    In the U.K., pubs can be seen everywhere. They play an important role in the British society. How pubs came into being in the U.K.? Why is pub culture formed and what makes it prosperous? What effects does pub culture make on British society both in the past and in the present? Does any British character be shown in pub culture in the U.K.? In this paper, I will give a brief in-troduction of pub culture's history and development in the U.K.. Besides, the above questions will be explored and analyzed one by one.

  10. The nutritional composition of British bread: London area study.

    Science.gov (United States)

    Sivell, L M; Wenlock, R W

    1983-12-01

    Samples of white and brown bread, both sliced and unsliced, and of wheatgerm breads and wholemeal bread were purchased in London and analysed for a wide range of nutrients. Available carbohydrate, dietary fibre, fatty acids, riboflavin, vitamin B6, and iodine were determined in bulked samples of each type of bread and, in addition, every loaf was analysed for moisture, fat, protein, phosphorus, chloride, sodium, potassium, calcium, magnesium, iron, zinc, copper, manganese, thiamin, nicotinic acid, and free and total folic acid, in order to provide an estimate the variability within each kind of bread. Virtually all the constituents that were measured in the individual loaves showed inter-loaf variation--particularly moisture contents and the levels of calcium, copper and folic acid. Unsliced loaves were more variable than sliced loaves but when expressed on a dry matter basis there were no significant differences in the nutrient levels in sliced and unsliced breads. Wheatgerm breads were relatively more homogenous products but wholemeal loaves were very unhomogenous reflecting the difficulty of accurately identifying unwrapped wholemeal loaves in retail outlets. Some differences from previously published values for all breads were found for dietary fibre, iron, thiamin and vitamin B6. Experience of sampling at retail outlets and analysis provided by this study will be integrated into the design of a planned study of breads throughout Britain.

  11. Occupy London und die besetzte Friern Barnet Library

    Directory of Open Access Journals (Sweden)

    Johannes Diesing

    2013-12-01

    Full Text Available Der Gegenstand des Beitrages ist die besetzte Friern Barnet Library in Nord-London. Dieser steht für eine ‚Politik des Politischen‘, die sich gegen die Privatisierungsmaßnahmen der regierenden liberal-konservativen Koalition richtet. In diesem Kampf um die Bibliothek wurden Aussagen der programmatischen Vision der Regierung von einer Allianz aus Aktivist_innen und Bürger_innen polemisch gegen die Politik gewendet, deren Umsetzung diese Vision ideologisch legitimieren sollte. Es werden zunächst die Rahmenbedingungen der Besetzung beschrieben, danach wird detailliert auf das Geschehen im Herbst 2012 und Winter 2012/13 eingegangen. Es wird erklärt, warum die Auseinandersetzung um die Bibliothek für das Verständnis gegenwärtiger sozialer Kämpfe in der ‚postpolitischen Stadt‘ hilfreich ist. Zum Begriff der Postpolitik bzw. der Postdemokratie haben sowohl Colin Crouch als auch Jacques Rancière Theorien vorgelegt. Der Aufsatz wird den theoretischen Schwerpunkt auf Rancière legen, Crouchs Überlegungen jedoch ebenfalls mit einbeziehen.

  12. Ethnic variations in orthodontic treatment need in London schoolchildren

    Directory of Open Access Journals (Sweden)

    Jopanputra Pooja

    2005-09-01

    Full Text Available Abstract Background The study was carried out to determine the prevalence of orthodontic treatment need in children from minority ethnic groups and compare the need to the white population. The second objective was to explore variations in agreement between subjective and objective treatment need in a multiethnic context using the aesthetic component of Orthodontic Treatment Need Index (IOTN AC. Methods A cross-sectional study in North West London, 14 schools were randomly selected from the 27 schools in the two boroughs of Harrow and Hillingdon. Comparison between objective and subjective treatment need was carried out using IOTN AC index. Clinical orthodontic treatment need was also recorded using the dental health component of Orthodontic Treatment Need Index (IOTN DHC. Results 2,788 children were examined and completed the questionnaire. 16% of the study population were already wearing appliances or had finished orthodontic treatment. Of the remaining children; 15% had definite need for treatment using the dental health component of the IOTN. There was no significant variation in the need for orthodontic treatment between different ethnic backgrounds (P > 0.05 whether using the AC or DHC components of the IOTN index. However, poor agreement was detected between professional and subjective assessment of ethnic minority of orthodontic treatment need using IOTN AC index. Conclusion Orthodontic treatment need in children of ethnic minorities does not differ significantly from the vast majority of white children. However treatment need based on aesthetic index continues to vary in all ethnic groups from the professional aesthetic assessment

  13. Healthcare planning for the Olympics in London: a qualitative evaluation.

    Directory of Open Access Journals (Sweden)

    Georgia Black

    Full Text Available BACKGROUND: Mass gatherings, such as the Olympic and Paralympic Games, represent an enormous logistical challenge for the host city. Health service planners must deliver routine and emergency services and, in recent Games, health legacy initiatives, for the local and visiting population. However there is little evidence to support their planning decisions. We therefore evaluated the strategic health planning programme for the London 2012 Olympic and Paralympic Games to identify generalisable information for future Games. METHODS: We thematically analysed data from stakeholder interviews and documents. The data were prospectively collected in three phases, before, during and after the Games. FINDINGS: We identified five key themes: (1 Systemic Improvement for example in communications, (2 Effective relationships led to efficiencies and permanent gains, such as new relationships with the private sector (3 Difficult relationships led to inefficiencies, for instance, duplication in testing and exercising emergency scenarios, (4 Tendency to over-estimate demand for care, particularly emergency medicine, and (5 Difficulties establishing a health legacy due to its deprioritisation and lack of vision by the programme team. INTERPRETATION: Enduring improvements which are sustained after the Games are possible, such as the establishment of new and productive partnerships. Relationships must be established early on to avoid duplication, delay and unnecessary expense. There should be greater critical evaluation of the likely demand for health services to reduce the wasting of resources. Finally, if a health legacy is planned, then clear definitions and commitment to its measurement is essential.

  14. The Dialectal Provenance of London, Wellcome Library, Ms 5262

    Directory of Open Access Journals (Sweden)

    Esteban-Segura Laura

    2014-12-01

    Full Text Available This paper takes into consideration the language found in London, Wellcome Library, MS 5262, a one-volume codex from the early fifteenth century which holds a medical recipe collection. The manuscript, written in Middle English (and with a few fragments in Latin, represents a fine exemplar of a remedybook, a type of writing that has been traditionally considered to be popular. The main aim is to study the dialect of the text contained in folios 3v-61v in order to localise it geographically. The methodology followed for the purpose is grounded on the model supplied by the Linguistic Atlas of Late Mediaeval English (LALME (McIntosh et al. 1986, which consists of several stages including the completion of a survey questionnaire, the creation of the linguistic profile of the text and the application of the ‘fit’-technique (McIntosh et al. 1986, vol. 1: 10-12; Benskin 1991. Extralinguistic features of the manuscript may also be taken into consideration. This comprehensive analysis will help us to circumscribe the dialectal provenance and/or local origin of the text accurately.

  15. Persistent sulfate formation from London Fog to Chinese haze

    Science.gov (United States)

    Wang, Gehui; Zhang, Renyi; Gomez, Mario E.; Yang, Lingxiao; Levy Zamora, Misti; Hu, Min; Lin, Yun; Peng, Jianfei; Guo, Song; Meng, Jingjing; Li, Jianjun; Cheng, Chunlei; Hu, Tafeng; Ren, Yanqin; Wang, Yuesi; Gao, Jian; Cao, Junji; An, Zhisheng; Zhou, Weijian; Li, Guohui; Wang, Jiayuan; Tian, Pengfei; Marrero-Ortiz, Wilmarie; Secrest, Jeremiah; Du, Zhuofei; Zheng, Jing; Shang, Dongjie; Zeng, Limin; Shao, Min; Wang, Weigang; Huang, Yao; Wang, Yuan; Zhu, Yujiao; Li, Yixin; Hu, Jiaxi; Pan, Bowen; Cai, Li; Cheng, Yuting; Ji, Yuemeng; Zhang, Fang; Rosenfeld, Daniel; Liss, Peter S.; Duce, Robert A.; Kolb, Charles E.; Molina, Mario J.

    2016-11-01

    Sulfate aerosols exert profound impacts on human and ecosystem health, weather, and climate, but their formation mechanism remains uncertain. Atmospheric models consistently underpredict sulfate levels under diverse environmental conditions. From atmospheric measurements in two Chinese megacities and complementary laboratory experiments, we show that the aqueous oxidation of SO2 by NO2 is key to efficient sulfate formation but is only feasible under two atmospheric conditions: on fine aerosols with high relative humidity and NH3 neutralization or under cloud conditions. Under polluted environments, this SO2 oxidation process leads to large sulfate production rates and promotes formation of nitrate and organic matter on aqueous particles, exacerbating severe haze development. Effective haze mitigation is achievable by intervening in the sulfate formation process with enforced NH3 and NO2 control measures. In addition to explaining the polluted episodes currently occurring in China and during the 1952 London Fog, this sulfate production mechanism is widespread, and our results suggest a way to tackle this growing problem in China and much of the developing world.

  16. The London polonium incident: lessons in risk communications.

    Science.gov (United States)

    Rubin, G James; Amlôt, Richard; Page, Lisa

    2011-11-01

    Public responses to large-scale radiological incidents are often thought to be disproportionate to the objective risk and can involve widespread societal disruption. Recent experiences of the (200)Po incident in central London suggest that public responses depend heavily on the nature of the incident and the effectiveness of risk communication efforts. This paper describes the outcome of several studies done in the aftermath of the (200)Po incident that suggest the reaction of the public on this occasion was muted, even for those directly affected. However, the desire for accurate, up-to-date and individually-tailored information was strong, and satisfaction with the efforts of the responding agencies was mediated by this information provision. A small minority of individuals was difficult to reassure effectively. This group may confer a particular drain on resources. Lessons for the risk communication efforts of public health responders are identified, in particular the importance of helping individuals to identify their risk of exposure, understand the difference between acute and chronic effects of exposure, and appreciate the meaning of any test results. Attempts at providing reassurance in the absence of specific information are likely to be counterproductive in any future radiological incident.

  17. Scaling and allometry in the building geometries of Greater London

    Science.gov (United States)

    Batty, M.; Carvalho, R.; Hudson-Smith, A.; Milton, R.; Smith, D.; Steadman, P.

    2008-06-01

    Many aggregate distributions of urban activities such as city sizes reveal scaling but hardly any work exists on the properties of spatial distributions within individual cities, notwithstanding considerable knowledge about their fractal structure. We redress this here by examining scaling relationships in a world city using data on the geometric properties of individual buildings. We first summarise how power laws can be used to approximate the size distributions of buildings, in analogy to city-size distributions which have been widely studied as rank-size and lognormal distributions following Zipf [ Human Behavior and the Principle of Least Effort (Addison-Wesley, Cambridge, 1949)] and Gibrat [ Les Inégalités Économiques (Librarie du Recueil Sirey, Paris, 1931)]. We then extend this analysis to allometric relationships between buildings in terms of their different geometric size properties. We present some preliminary analysis of building heights from the Emporis database which suggests very strong scaling in world cities. The data base for Greater London is then introduced from which we extract 3.6 million buildings whose scaling properties we explore. We examine key allometric relationships between these different properties illustrating how building shape changes according to size, and we extend this analysis to the classification of buildings according to land use types. We conclude with an analysis of two-point correlation functions of building geometries which supports our non-spatial analysis of scaling.

  18. Nutritional knowledge of UK coaches.

    Science.gov (United States)

    Cockburn, Emma; Fortune, Alistair; Briggs, Marc; Rumbold, Penny

    2014-04-10

    Athletes obtain nutritional information from their coaches, yet their competency in this area is lacking. Currently, no research exists in the UK which has a different coach education system to many other countries. Therefore, the aim of this study was to evaluate the sports nutrition knowledge of UK coaching certificate (UKCC) level 2 and 3, hockey and netball qualified coaches. All coaches (n = 163) completed a sports nutrition questionnaire to identify: (a) if they provided nutritional advice; (b) their level of sport nutrition knowledge; and (c) factors that may have contributed to their level of knowledge. Over half the coaches provided advice to their athletes (n = 93, 57.1%), even though they were not competent to do so. Coaches responded correctly to 60.3 ± 10.5% of all knowledge questions with no differences between those providing advice and those who did not (p > 0.05). Those coaches who had undertaken formal nutrition training achieved higher scores than those who had not (p sports coaches would benefit from continued professional development in sports nutrition to enhance their coaching practice.

  19. Environmental enforcement in the UK.

    Science.gov (United States)

    Stott, David

    2009-03-01

    In the UK, the Environment Agency is responsible for enforcement of environmental legislation and offences committed under such laws and regulations. Under the current regime, if deemed serious enough, offenders are taken to court. In the past eight years, there have been approximately 1600 cases (including approximately 800 prosecutions) per year with 61% being for illegal disposal of wastes and a further 26% being for water pollution incidents. The level of fine has been relatively small at around pound sterling 6700 per conviction for water offences and pound sterling 3700 for waste offences. This is possibly due to a lack of awareness of the damage caused in environmental offending by the courts. New legislation in the form of the Regulatory Enforcement and Sanctions Act 2008 is likely to change the way offences are assessed and treated by the Agency and a proportion of cases will be dealt with by the Agency itself, with appeals being handled by a Tribunal and only the most serious cases going to the criminal courts. The efficacy of this approach has yet to be tested in the UK but may speed up the process and lead to more appropriate sanctions being levied.

  20. The CCCB is a cultural centre, not a tourist centre

    Directory of Open Access Journals (Sweden)

    Elena Xirau

    2004-04-01

    Full Text Available Last February, Barcelona's Centre of Contemporary Culture (CCCB celebrated its first ten years in existence. During this time, this institution has looked to be a showcase to the most modern and innovative cultural expressions focused on reflecting on the concept of the city. In this interview, Josep Ramoneda offers his personal view, as the CCCB's director. He talks of how this cultural project was born, of how the concept of the institution took shape in the CCCB, of its relations with Barcelona's Strategic Plan, of how the project has evolved, of the architectural remodelling of the Casa de la Caritat building for its conversion into a cultural centre, of the relations with other institutions and its future.