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Sample records for centre anticipated benefits

  1. Anticipating the Economic Benefits of Blockchain

    Melanie Swan

    2017-01-01

    In this general overview article intended for non-experts, I define blockchain technology and some of the key concepts, and then I elaborate four specific applications that highlight the potential economic benefits of digital ledgers. These applications are digital asset registries, blockchains as leapfrog technology for global financial inclusion, long-tail personalized economic services, and net settlement payment channels. I also highlight key challenges that offset the potential economic ...

  2. Anticipating the Economic Benefits of Blockchain

    Melanie Swan

    2017-10-01

    Full Text Available In this general overview article intended for non-experts, I define blockchain technology and some of the key concepts, and then I elaborate four specific applications that highlight the potential economic benefits of digital ledgers. These applications are digital asset registries, blockchains as leapfrog technology for global financial inclusion, long-tail personalized economic services, and net settlement payment channels. I also highlight key challenges that offset the potential economic benefits of blockchain distributed ledgers, while arguing that the benefits would outweigh the potential risks. The overarching theme is that an increasing amount of everyday operations involving money, assets, and documents could start to be conducted via blockchain-based distributed network ledgers with cryptographic security, and at more granular levels of detail. One economic implication of widespread blockchain adoption is that the institutional structure of society could shift to one that is computationally-based and thus has a diminished need for human-operated brick-and-mortar institutions.

  3. Antenatal corticosteroids: an assessment of anticipated benefits and potential risks.

    Jobe, Alan H; Goldenberg, Robert L

    2018-04-07

    Antenatal corticosteroids are standard of care for pregnancies at risk of preterm delivery between 24-34 weeks' gestational age. Recent trials demonstrate modest benefits from antenatal corticosteroids for late preterm and elective cesarean deliveries, and antenatal corticosteroids for periviable deliveries should be considered with family discussion. However, many women with threatened preterm deliveries receive antenatal corticosteroids but do not deliver until >34 weeks or at term. The net effect is that a substantial fraction of the delivery population will be exposed to antenatal corticosteroids. There are gaps in accurate assessments of benefits of antenatal corticosteroids because the randomized controlled trials were performed prior to about 1990 in pregnancies generally >28 weeks. The care practices for the mother and infant survival were different than today. The randomized controlled trial data also do not strongly support the optimal interval from antenatal corticosteroid treatment to delivery of 1-7 days. Epidemiology-based studies using large cohorts with >85% of at-risk pregnancies treated with antenatal corticosteroids probably overestimate the benefits of antenatal corticosteroids. Although most of the prematurity-associated mortality is in low-resource environments, the efficacy and safety of antenatal corticosteroids in those environments remain to be evaluated. The short-term benefits of antenatal corticosteroids for high-risk pregnancies in high-resource environments certainly justify antenatal corticosteroids as few risks have been identified over many years. However, cardiovascular and metabolic abnormalities have been identified in large animal models and cohorts of children exposed to antenatal corticosteroids that are consistent with fetal programming for adult diseases. These late effects of antenatal corticosteroids suggest caution for the expanded use of antenatal corticosteroids beyond at-risk pregnancies at 24-34 weeks. A way forward

  4. Anticipated Benefits of Care (ABC): psychometrics and predictive value in psychiatric disorders.

    Warden, D; Trivedi, M H; Carmody, T J; Gollan, J K; Kashner, T M; Lind, L; Crismon, M L; Rush, A J

    2010-06-01

    Attitudes and expectations about treatment have been associated with symptomatic outcomes, adherence and utilization in patients with psychiatric disorders. No measure of patients' anticipated benefits of treatment on domains of everyday functioning has previously been available. The Anticipated Benefits of Care (ABC) is a new, 10-item questionnaire used to measure patient expectations about the impact of treatment on domains of everyday functioning. The ABC was collected at baseline in adult out-patients with major depressive disorder (MDD) (n=528), bipolar disorder (n=395) and schizophrenia (n=447) in the Texas Medication Algorithm Project (TMAP). Psychometric properties of the ABC were assessed, and the association of ABC scores with treatment response at 3 months was evaluated. Evaluation of the ABC's internal consistency yielded Cronbach's alpha of 0.90-0.92 for patients across disorders. Factor analysis showed that the ABC was unidimensional for all patients and for patients with each disorder. For patients with MDD, lower anticipated benefits of treatment was associated with less symptom improvement and lower odds of treatment response [odds ratio (OR) 0.72, 95% confidence interval (CI) 0.57-0.87, p=0.0011]. There was no association between ABC and symptom improvement or treatment response for patients with bipolar disorder or schizophrenia, possibly because these patients had modest benefits with treatment. The ABC is the first self-report that measures patient expectations about the benefits of treatment on everyday functioning, filling an important gap in available assessments of attitudes and expectations about treatment. The ABC is simple, easy to use, and has acceptable psychometric properties for use in research or clinical settings.

  5. Centres for People with Intellectual Disabilities: Attendees' Perceptions of Benefit

    Gajewska, Urszula; Trigg, Richard

    2016-01-01

    Background: Day and community learning centres aim to provide intellectually disabled (ID) people with social support, life skills and greater control over their lives. However, there is little research exploring the benefits of attendance from the perspective of attendees and whether these goals are met. Materials and methods: Unstructured…

  6. Electronic medical record systems in critical access hospitals: leadership perspectives on anticipated and realized benefits.

    Mills, Troy R; Vavroch, Jared; Bahensky, James A; Ward, Marcia M

    2010-04-01

    The growth of electronic medical records (EMRs) is driven by the belief that EMRs will significantly improve healthcare providers' performance and reduce healthcare costs. Evidence supporting these beliefs is limited, especially for small rural hospitals. A survey that focused on health information technology (HIT) capacity was administered to all hospitals in Iowa. Structured interviews were conducted with the leadership at 15 critical access hospitals (CAHs) that had implemented EMRs in order to assess the perceived benefits of operational EMRs. The results indicate that most of the hospitals implemented EMRs to improve efficiency, timely access, and quality. Many CAH leaders also viewed EMR implementation as a necessary business strategy to remain viable and improve financial performance. While some reasons reflect external influences, such as perceived future federal mandates, other reasons suggest that the decision was driven by internal forces, including the hospital's culture and the desires of key leaders to embrace HIT. Anticipated benefits were consistent with goals; however, realized benefits were rarely obvious in terms of quantifiable results. These findings expand the limited research on the rationale for implementing EMRs in critical access hospitals.

  7. Freshman College Students' Reasons for Enrolling in and Anticipated Benefits from a Basic College Physical Education Activity Course.

    Lackman, Jeremy; Smith, Matthew Lee; McNeill, Elisa Beth

    2015-01-01

    Given the rise in US obesity rates in adulthood, efforts are needed to assess physical activity engagement during the college years as a strategy to promote a lifetime of being physically active. This study identifies the reasons incoming college freshman enrolled in basic physical education activity courses (BPEAC) and the perceived benefits they anticipated receiving as a result of course participation. Data collected from 302 college freshmen in September 2013 were analyzed. A paper-based questionnaire was administered to 78% of BPEAC sections offered at a large Southeastern University. Frequencies were presented for all participants, which were then compared by sex and course type. Kappa statistics were calculated to examine the concordance between participants' reasons for enrolling in the course and the benefits they anticipated from course enrollment. Diverse physical, mental, social, and academic reasons for enrolling in BPEAC were reported by study participants. Varied anticipated benefits from course participation were reported as well. Reported enrollment reasons and anticipated benefits differed by sex and course type. High concordance between matched enrollment reasons and anticipated benefits was observed. Implications highlight the need for universities to provide quality BPEAC, promote high-quality instruction, and offer a wide variety of physical education courses to meet the diverse needs of students.

  8. How to anticipate the assessment of the public health benefit of new medicines?

    Massol, Jacques; Puech, Alain; Boissel, Jean-Pierre

    2007-01-01

    The Public Health Benefit (PHB) of new medicines is a recent and French-specific criterion (October 1999 decree) which is often only partially documented in the transparency files due to a lack of timely information. At the time of the first reimbursement application for a new medicine to the "Transparency Committee", the file is exclusively based on data from randomised clinical trials. These data are generated from a global clinical development plan which was designed a long time before the new medicine's submission for reimbursement. And this plan does not systematically provide the data needed to assess the PHB. Thus, one easily understands the difficulty to anticipate and document this recent French criterion. In France, the PHB is both one of the necessary criteria for the reimbursement submission and an indicator for the national health policy management. Its assessment also helps to identify the needs and objectives of the post-registration studies (nowadays in the scope of responsibilities of the "Drug Economics Committee"). The assessment of the PHB criterion is carried through after the marketing authorization process and is an addition to it. To understand how to anticipate the assessment of the new medicines' PHB, one needs to consider how it differs from the preliminary step of the marketing authorization process. Whereas the evaluation for marketing authorization seeks to determine if the new medicine could be useful in a specific indication, the PHB assessment aims at quantifying the therapeutic benefit in a population, taking into account the reference treatments in this population. A new medicine receives a marketing authorization based on the data of the registration file which provides information on the clinical benefit of the new medicine in the populations of the trials and in the context of the trials. On the other side, the PHB looks at the effects of the new medicine at the scale of the general population, in real practice. The PHB

  9. The anticipated costs analysis and benefit items survey against performing the maintenance rule

    Hwang, M. J.; Kim, K. Y.; Yang, Z. A.

    2002-01-01

    In this paper, we surveyed the cost and benefit items and evaluated the costs against performing the Maintenance Rule. In the past, only one electric power company had provided the electricity without free competition in Korea. In these days, however, the electric power company was divided into two parts by the sources: atomic and hydraulic generation and thermal-power generation. Therefore, the generation sources that done have competitiveness at the price will be weeded out in the electric power market. Although the preferential goal is on the safe operation at the Nuclear power Plants (NPPs), if too much money is required to maintain or improve the safety of the NPP, the licensee could hesitate to adopt the program related to the safety even though it is a good one. Since the Risk-Informed Applications (RIA) have been using for a plant operation in recent, the condition of a plant might be changed. Therefore, considering the affects of the RIA, a method to keep the capability through the monitoring the maintenance effectiveness has been proposed. However, to perform this, a number of works, continuous collecting data and monitoring the maintenance effectiveness and understanding the reason of degrading capability, should be preceded. Therefore, a lot of man-hour is needed to develop and to manage the application method, and the licensee should pay the costs. Therefore, in the domestic circumstance, it is necessary to evaluate the cost to monitor the maintenance effectiveness. Hence, we are going to examine the cost to perform the MR and its anticipated benefit lists

  10. Motivation for orthognathic treatment and anticipated satisfaction levels-a two-centre cross-national audit.

    Patcas, Raphael; Cunningham, Susan J; Shute, Justin; Lloyd, Timothy; Obwegeser, Joachim A; Arjomand, Lida; Sharma, Sujata

    2017-06-01

    This audit investigated factors which motivate patients to seek orthognathic treatment, assessed how confident patients were that they would be satisfied with the outcome of treatment, and explored possible influencing factors. Questionnaires were distributed to pre-surgical patients at two centres (United Kingdom and Switzerland); questions asked what patients wished to gain from orthognathic treatment and how confident they were that they would be satisfied with treatment outcome. Gender, age and location were recorded as demographic variables, and type of malocclusion was also recorded. A total of 202 questionnaires were returned (UK, n = 149; Switzerland, n = 53). Reported motivating factors focused on improvements in aesthetics (specified and unspecified) (UK vs. Switzerland: 91.3% vs. 83.0%), function (72.5% vs. 66.0%), psychosocial health (51.7% vs. 20.8%), speech (4.0% vs. 7.5%), alleviation of pain (5.4% vs. 17%) and normalization of breathing (1.3% vs. 7.5%). No significant relationships were observed relative to patient age, gender or malocclusion. The anticipated satisfaction levels were generally high (86.5% vs. 89.9%). Although the distribution of motivational factors varied between the two sites, it did not affect the anticipated satisfaction level. Patients were generally confident that they would be satisfied with their treatment outcome and that their reasons for seeking treatment would be addressed. Copyright © 2017 European Association for Cranio-Maxillo-Facial Surgery. All rights reserved.

  11. The benefit of issue management: anticipating crises in the digital age

    Strauβ, N.; Jonkman, J.

    2017-01-01

    Purpose The purpose of this paper is to find out how issue management and media monitoring is exercised in the digital age to anticipate crises. More specifically, it was investigated how these practices differ across communication professionals, organizations, and sectors in the Netherlands.

  12. Freshman College Students’ Reasons for Enrolling in and Anticipated Benefits from a Basic College Physical Education Activity Course

    Lackman, Jeremy; Smith, Matthew Lee; McNeill, Elisa Beth

    2015-01-01

    Background Given the rise in US obesity rates in adulthood, efforts are needed to assess physical activity engagement during the college years as a strategy to promote a lifetime of being physically active. This study identifies the reasons incoming college freshman enrolled in basic physical education activity courses (BPEAC) and the perceived benefits they anticipated receiving as a result of course participation. Methods Data collected from 302 college freshmen in September 2013...

  13. The programme benefits of improving project team communication through a contact centre

    Bond-Barnard, T. J.

    2013-08-01

    Full Text Available A South African national programme to repair government infrastructure uses a contact centre (or call centre to facilitate and manage communication. An important question is: How does the contact centre benefit the programme and its projects? This study discusses the findings of a survey that quantified the benefits of the programme when the communication between team members in the programme was improved by using a contact centre. The results show that, by using a contact centre to improve the communication between project team members, their perception of communication effectiveness, quality of project deliverables, service delivery, and customer satisfaction of the programme dramatically increases.

  14. Cost-benefit analysis of irradiation of vegetables and fruits at the Shanghai irradiation centre

    Xu Zhicheng; Sha Zhenyuan

    1993-01-01

    Differences between the developing and the developed countries in development and application of food irradiation are discussed, including the objectives of irradiation, scale, and the operation and control of facilities. These represent the chief problems of development of food irradiation in the developing countries. A proposal concerning the economic benefit of a gamma irradiation facility is discussed. In the light of many years' operating experience at the Shanghai Irradiation Centre, the operation cost per hour and coefficient of economic benefit are presented. These data can be used to estimate the economic benefit of gamma irradiated products at any time, and are useful for directing the daily operation of gamma irradiation facilities. From examples of cost-benefit analysis of irradiated garlic and apples it is shown that to improve the benefit of gamma irradiation facilities the annual hours of operation must be increased, so as to reduce the cost of operation. Food irradiated with a low dose provides more economic benefit than other irradiated products; the coefficients of economic benefit will increase as the irradiated processing throughput increases. Practical examples are given relating to garlic and apples, showing the economic benefit to wholesalers and retailers. (author). 4 refs, 3 figs, 7 tabs

  15. Anticipated regret

    Zeelenberg, M.; Parrott, R.

    2018-01-01

    Regret is the prototypical decision related emotion. It is felt when the outcome of a non-chosen alternative is better than the outcomes obtained. Regret is a functional emotion that helps people to correct mistakes. It is also functional because people can anticipate regret beforehand, then choose

  16. Climate Innovation Centres. A global instrument with local benefits. Policy brief

    De Coninck, H.C.; Rivera Tinoco, R.A.

    2010-09-01

    A climate innovation centre is an institution aimed at enabling development through catalyzing climate technology research, development and market creation. What do technologies need to flourish and to contribute to sustainable economic development? Current research suggests that functioning markets, innovative capacities and the availability of appropriate technology in countries such as Ghana are key. In the climate negotiations, climate technology innovation centres, as well as an international network of them is in the process of agreement, providing opportunities for Ghana. This Policy Brief explains the considerations for a climate innovation centre in Ghana. It goes into the climate negotiations context, the practical choices for Ghana, gives examples of other countries, and outlines the next steps in the ECN Technical Assistance project.

  17. National data centres and other means of regional cooperation in Africa: prospects and benefits

    Masawi, L.

    2002-01-01

    Participation in regional cooperation by Bulawayo National Data Centre in Zimbabwe is noted. East and Southern Africa Working Group (ESAWORG) is given as an example of such cooperation. The coming of CTBT is expected to strengthen the said group together with regional cooperation. Expected new developments are listed

  18. Safety and cost benefit of an ambulatory program for patients with low-risk neutropenic fever at an Australian centre.

    Teh, Benjamin W; Brown, Christine; Joyce, Trish; Worth, Leon J; Slavin, Monica A; Thursky, Karin A

    2018-03-01

    Neutropenic fever (NF) is a common complication of cancer chemotherapy. Patients at low risk of medical complications from NF can be identified using a validated risk assessment and managed in an outpatient setting. This is a new model of care for Australia. This study described the implementation of a sustainable ambulatory program for NF at a tertiary cancer centre over a 12-month period. Peter MacCallum Cancer Centre introduced an ambulatory care program in 2014, which identified low-risk NF patients, promoted early de-escalation to oral antibiotics, and early discharge to a nurse-led ambulatory program. Patients prospectively enrolled in the ambulatory program were compared with a historical-matched cohort of patients from 2011 for analysis. Patient demographics, clinical variables (cancer type, recent chemotherapy, treatment intent, site of presentation) and outcomes were collected and compared. Total cost of inpatient admissions was determined from diagnosis-related group (DRG) codes and applied to both the prospective and historical cohorts to allow comparisons. Twenty-five patients were managed in the first year of this program with a reduction in hospital median length of stay from 4.0 to 1.1 days and admission cost from Australian dollars ($AUD) 8580 to $AUD2360 compared to the historical cohort. Offsetting salary costs, the ambulatory program had a net cost benefit of $AUD 71895. Readmission for fever was infrequent (8.0%), and no deaths were reported. Of relevance to hospitals providing cancer care, feasibility, safety, and cost benefits of an ambulatory program for low-risk NF patients have been demonstrated.

  19. Anticipation and medicine

    2017-01-01

    In this book, practicing physicians and experts in anticipation present arguments for a new understanding of medicine. Their contributions make it clear that medicine is the decisive test for anticipation. The reader is presented with a provocative hypothesis: If medicine will align itself with the anticipatory condition of life, it can prompt the most important revolution in our time. To this end, all stakeholders—medical practitioners, patients, scientists, and technology developers—will have to engage in the conversation. The book makes the case for the transition from expensive, and only marginally effective, reactive treatment through “spare parts” (joint replacements, organ transplants) and reliance on pharmaceuticals (antibiotics, opiates) to anticipation-informed healthcare. Readers will understand why the current premise of treating various behavioral conditions (attention deficit disorder, hyperactivity, schizophrenia) through drugs has to be re-evaluated from the perspective of anticipation...

  20. Personal anticipated information need

    H. Bruce

    2005-01-01

    Full Text Available Background. The role of personal information collections is a well known feature of personal information management. The World Wide Web has introduced to such collections ideas such as filing Web pages or noting their existence in 'Bookmarks' and 'Favourites'. Argument. It is suggested that personal information collections are created in anticipation of some future need for that information-personal, anticipated information need, which also underlies the design of formal information systems. Elaboration. Examination of the literature of information needs and information seeking behaviour leads to the formulation of five propositions that elaborate the concept of personal, anticipated information need. These propositions draw upon concepts such as uncertainty, predictability, sensitivity and the valuation of information sources. Conclusion. An individual's understanding of personal, anticipated information need and how this understanding guides the acquisition and management of personal information will determine the effectiveness of that collection.

  1. Personal anticipated information need

    H. Bruce

    2005-01-01

    Background. The role of personal information collections is a well known feature of personal information management. The World Wide Web has introduced to such collections ideas such as filing Web pages or noting their existence in 'Bookmarks' and 'Favourites'. Argument. It is suggested that personal information collections are created in anticipation of some future need for that information-personal, anticipated information need, which also underlies the design of formal information systems. ...

  2. Anticipation across disciplines

    2016-01-01

    Never before was anticipation more relevant to the life and activity of humankind than it is today. “It is no overstatement to suggest that humanity’s future will be shaped by its capacity to anticipate….” (Research Agenda for the 21st Century, National Science Foundation). The sciences and the humanities can no longer risk explaining away the complexity and interactivity that lie at the foundation of life and living. The perspective of the world that anticipation opens justifies the descriptor “the post-Cartesian Revolution.” If anticipation is a valid research domain, what practical relevance can we await? Indeed, anticipation is more than just the latest catch-word in marketing the apps developed by the digital technology industry. Due to spectacular advances in the study of the living, anticipation can claim a legitimate place in current investigations and applications in the sciences and the humanities. Biology, genetics, medicine, as well as politics and cognitive, behavioral, and social sci...

  3. Anticipation in sport.

    Loffing, Florian; Cañal-Bruland, Rouwen

    2017-08-01

    Anticipation has become an increasingly important research area within sport psychology since its infancy in the late 1970s. Early work has increased our fundamental understanding of skilled anticipation in sports and how this skill is developed. With increasing theoretical and practical insights and concurrent technological advancements, researchers are now able to tackle more detailed questions with sophisticated methods. Despite this welcomed progress, some fundamental questions and challenges remain to be addressed, including the (relative) contributions of visual and motor experience to anticipation, intraindividual and interindividual variation in gaze behaviour, and the impact of non-kinematic (contextual or situational) information on performance and its interaction with advanced kinematic cues during the planning and execution of (re)actions in sport. The aim of this opinion paper is to shortly sketch the state of the art, and then to discuss recent work that has started to systematically address open challenges thereby inspiring promising future routes for research on anticipation and its application in practice. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. The Health and Safety Benefits of New Technologies in Mining: A Review and Strategy for Designing and Deploying Effective User-Centred Systems

    Tim Horberry

    2012-10-01

    Full Text Available Mining is currently experiencing a rapid growth in the development and uptake of automation and other new technologies (such as collision detection systems; however, they are often developed from a technology-centred perspective that does not explicitly consider the end-user. This paper first presents a review of the technologies currently available (or near-market and the likely human factors issues associated with them. The second part of the paper presents a potential long term strategy for research and development that aims to maximise the safety and health benefits for operators of such new technologies. The strategy includes a four stage research and development process, this covers: better understanding the needs for technology, user requirements and risk/cost analysis; human element design, procurement and deployment processes; evaluation and verification of the strategy; and dissemination of it to relevant stakeholders (including equipment manufacturers, mine site purchasers and regulators. The paper concludes by stressing the importance of considering the human element with respect to new mining technologies and the likely benefits of adopting the type of strategy proposed here. The overall vision is for mining to become safer and healthier through effective user-centred design and deployment of new technologies that serve both operator needs and the demands of the workplace.

  5. Anticipating Organizational Change

    Krogh, Simon

    This study reports on the extended time period prior to the introduction of the largest ever Health IT implementation in Denmark – Sundhedsplatformen. The focus of the dissertation is on organizational implications of introducing new technology and more specifically the anticipation...... of organizational members waiting for changes to take effect. The 3-year period leading up to the ‘go-live’ of Sundhedsplatformen has been a unique opportunity to study the anticipatory phase in connection with large scale IT project and has resulted in the development of a theoretical / conceptual framework...

  6. Embodied Anticipation: A Neurodevelopmental Interpretation

    Kinsbourne, Marcel; Jordan, J. Scott

    2009-01-01

    This article proposes an approach to the brain's role in communication that treats the brain as the vehicle of a multi-scale embodiment of anticipation. Instead of conceptualizing anticipation as something a brain is able to do when circumstances seem to require it, this study proposes that anticipation is continuous and ongoing because to…

  7. Anticipated transients without scram

    Lellouche, G.S.

    1980-01-01

    This article discusses in various degrees of depth the publications WASH-1270, WASH-1400, and NUREG-0460, and has as its purpose a description of the technical work done by Electric Power Research Institute (EPRI) personnel and its contractors on the subject of anticipated transients without scram (ATWS). It demonstrates the close relation between the probability of scram failure derived from historical scram data and that derived from the use of component data in a model of a system (the so-called synthesis method), such as was done in WASH-1400. The inherent conservatism of these models is demonstrated by showing that they predict significantly more events than have in fact occurred and that such models still predict scram failure probabilities low enough to make ATWS an insignificant contributor to accident risk

  8. Can Cavitation Be Anticipated?

    Allgood, G.O.; Dress, W.B.; Hylton, J.O.; Kercel, S.W.

    1999-04-25

    The major problem with cavitation in pumps and hydraulic systems is that there is no effective (conventional) method for detecting or predicting its inception. The traditional method of recognizing cavitation in a pump is to declare the event occurring when the total head drops by some arbitrary value (typically 3%) in response to a pressure reduction at the pump inlet. However, the device is already seriously cavitating when this happens. What is actually needed is a practical method to detect impending rather than incipient cavitation. Whereas the detection of incipient cavitation requires the detection of features just after cavitation starts, the anticipation of cavitation requires the detection and identification of precursor features just before it begins. Two recent advances that make this detection possible. The first is acoustic sensors with a bandwidth of 1 MHz and a dynamic range of 80 dB that preserve the fine details of the features when subjected to coarse vibrations. The second is the application of Bayesian parameter estimation which makes it possible to separate weak signals, such as those present in cavitation precursors, from strong signals, such as pump vibration. Bayesian parameter estimation derives a model based on cavitation hydrodynamics and produces a figure of merit of how well it fits the acquired data. Applying this model to an anticipatory engine should lead to a reliable method of anticipating cavitation before it occurs. This paper reports the findings of precursor features using high-performance sensors and Bayesian analysis of weak acoustic emissions in the 100-1000kHz band from an experimental flow loop.

  9. Management benefits and safety of computed tomography in patients undergoing extracorporeal membrane oxygenation therapy: experience of a single centre

    Jepson, S.L.; Harvey, C.; Entwisle, J.J.; Peek, G.J.

    2010-01-01

    Aim: To evaluate the benefits and logistical safety of computed tomography (CT) imaging in patients undergoing extracorporeal membrane oxygenation (ECMO) therapy in a single institution. Materials and methods: Over a period of 25 months, 134 patients (80 neonates, 19 children, and 35 adults) underwent ECMO therapy at this institution. The imaging of these patients was reviewed to identify patients who had undergone CT imaging whilst on ECMO. Patient notes were retrospectively reviewed. CT findings and subsequent decisions were analysed to assess the benefit of CT imaging. Complications arising due to the logistics of performing the scan were analysed to assess the safety of performing CT in ECMO patients. Results: Of 134 patients, 14 (10%) had a total of 15 CT examinations whilst undergoing ECMO therapy. Indications for CT included new neurology, increased respiratory demand, and increasing requirement for high ECMO flows. There were no major complications and two minor complications associated with the logistics of performing a CT examination on an ECMO patient. Significant findings resulted from 73.3% (11/15) of the CT examinations, and in all 15 examinations information was provided that was used in making further management decisions, including, in some cases, withdrawal of ECMO therapy. Conclusion: With an experienced team, CT imaging of patients on ECMO can be performed safely. CT provides valuable information for subsequent management of patients undergoing ECMO therapy.

  10. L'anticipation comme actualisation

    Mondeme, Chloé

    2018-01-01

    It is commonly stated that anticipation is a phenomenon that is prior to a given action or situation, both time-wise and logically speaking. In this article, we focus in detail on how anticipation reconfigures the very action being anticipated. By ‘in detail’, we mean through the meticulous...... observation and analysis of ordinary interactions. The corpus is constituted of learning interactions, between dog educator and dogs in formation, in which anticipating an action, notably by assessing it before it happens, contributes in a large part to (re)configure it. This point leads us to develop...

  11. Cost-effectiveness analysis of offering free leisure centre memberships to physically inactive members of the public receiving state benefits: a case study.

    Verhoef, Talitha I; Trend, Verena; Kelly, Barry; Robinson, Nigel; Fox, Paul; Morris, Stephen

    2016-07-22

    We evaluated the cost-effectiveness of the Give-it-a-Go programme, which offers free leisure centre memberships to physically inactive members of the public in a single London Borough receiving state benefits. A decision analytic Markov model was developed to analyse lifetime costs and quality-adjusted life-years (QALYs) of 1025 people recruited to the intervention versus no intervention. In the intervention group, people were offered 4 months of free membership at a leisure centre. Physical activity levels were assessed at 0 and 4 months using the International Physical Activity Questionnaire (IPAQ). Higher levels of physical activity were assumed to decrease the risk of coronary heart disease, stroke and diabetes mellitus type II, as well as improve mental health. Costs were assessed from a National Health Service (NHS) perspective. Uncertainty was assessed using one-way and probabilistic sensitivity analyses. One-hundred fifty nine participants (15.5 %) completed the programme by attending the leisure centre for 4 months. Compared with no intervention, Give it a Go increased costs by £67.25 and QALYs by 0.0033 (equivalent to 1.21 days in full health) per recruited person. The incremental costs per QALY gained were £20,347. The results were highly sensitive to the magnitude of mental health gain due to physical activity and the duration of the effect of the programme (1 year in the base case analysis). When the mental health gain was omitted from the analysis, the incremental cost per QALY gained increased to almost £1.5 million. In the probabilistic sensitivity analysis, the incremental costs per QALY gained were below £20,000 in 39 % of the 5000 simulations. Give it a Go did not significantly increase life-expectancy, but had a positive influence on quality of life due to the mental health gain of physical activity. If the increase in physical activity caused by Give it a Go lasts for more than 1 year, the programme would be cost-effective given a

  12. Game 'life' with anticipation property

    Makarenko, A.; Goldengorin, B.; Krushynskyi, D.; Umeo, H.; Morishita, S.; Nishinari, K.; Komatsuzaki, T.; Bandini, S.

    2008-01-01

    Mechanisms of endowing cellular automata (CA) models with anticipation property are considered. As a background for investigation a widely known Conway’s game of ‘Life’ was chosen. Even within this simple model, introduction of anticipation has a crucial impact on the behavior of the system,

  13. PERAN ANTICIPATED EMOTION, HASRAT DAN NIAT BERKUNJUNG PADA FREKUENSI KUNJUNGAN PUSAT PERBELANJAAN

    Sari, E. Nadia Maya

    2014-01-01

    Hunter (2006) states that the image of a shopping centre is one of the factors that may increase the frequency of visits. In addition, the anticipated emotion that the customers experience during shopping is also a variable that influences the frequency of visits. The customers that have emotional relationship with a shopping centre have a higher desire to visit the related shopping centre. The customers’ higher desire to visit the shopping centre will influence the increasing intention to vi...

  14. 300 Junior Novel Anticipation Guides

    Polette, Nancy

    2006-01-01

    In this book, the author has created reproducible anticipation guides to 300 popular junior novels (grades 4-8) ranging from classics like Ben and Me and Cricket in Times Square to the current award winner, Kira, Kira. The book consists of 300 reproducible sets of open ended values questions to pique the interest of readers. Librarians and…

  15. Liturgy as space for anticipation

    2011-05-04

    May 4, 2011 ... It is anticipation without answer; expectation without event ... conversing, arguing, singing, playing games, exercising, swapping hats and contemplating suicide. In effect, they ... of time, as it is about the infinituding of time and people's experience .... could include all four of the aforementioned categories. In.

  16. Reactive behavior, learning, and anticipation

    Whitehead, Steven D.; Ballard, Dana H.

    1989-01-01

    Reactive systems always act, thinking only long enough to 'look up' the action to execute. Traditional planning systems think a lot, and act only after generating fairly precise plans. Each represents an endpoint on a spectrum. It is argued that primitive forms of reasoning, like anticipation, play an important role in reducing the cost of learning and that the decision to act or think should be based on the uncertainty associated with the utility of executing an action in a particular situation. An architecture for an adaptable reactive system is presented and it is shown how it can be augmented with a simple anticipation mechanism that can substantially reduce the cost and time of learning.

  17. Replicating the Networking, Mentoring and Venture Creation Benefits of Entrepreneurship Centres on a Shoestring: A Student-Centered Approach to Entrepreneurship Education and Venture Creation

    Bell, Robin; Bell, Heather

    2016-01-01

    As support for both university-level entrepreneurship education and the use of experiential learning methods to foster student entrepreneurs has increased, so too has the number of university-established or affiliated entrepreneurship centres. This study focuses on an activity designed to combine experiential learning methods with assets…

  18. Needs of anticipation for transport operations

    Galtier, J.

    2005-01-01

    COGEMA LOGISTICS (formerly Transnucleaire) has designed and manufactured several thousands of casks, and owns fleet of more than 4000 casks. Benefiting from more than 40 years of experience in cask shipment COGEMA LOGISTICS has demonstrated an outstanding performance in transportation and has integrated all feed back from past successful operations in current ones. Early anticipation of needs, i.e. at preliminary design step, is of major importance from a technical point of view (capacity, interface, handling means, licensing), and also in terms of political and public acceptance issues from the design step. This paper will highlight for each step required for the implementation of an optimal transport and storage system: Decision to proceed (including political aspects)-Design of casks to be used (including operational interface)-Licensing process-Manufacturing process-Transport plan, Public Acceptance-Loading Operations-Transport-Maintenance operations. (authors)

  19. Anticipating flow assurance challenges through geochemistry

    Flannery, M. [Fluid Evaluation and Sampling Technologies (FEAST) Team, Shell International Exploration and Production (United Kingdom)

    2008-07-01

    The behaviour of reservoir fluids pose a challenge at all stages of petroleum production, from the reservoir to refinery. The challenges sometimes stem from sub-optimal operations or inappropriate system design, with assumptions of similar fluid properties across the field. Hydrocarbon fluid phase behaviour is the product of local PVT conditions and the geochemical identity of the fluids. An appropriate development scenario along with anticipation of production challenges, can benefit from early integration of engineering and geochemical understanding of hydrocarbon fluids. This paper presented field examples of how the kerogen type and maturity, and later post-generation alteration processes such as biodegradation, water washing, TSR can influence likely flow assurance challenges in the production stream. The confounding issues of multiple charges and overlaying signatures were also discussed.

  20. Time discounting and pain anticipation. Experimental evidence

    Brañas Garza, Pablo

    2012-03-01

    Full Text Available This paper deals with pain anticipation experienced before medical procedures. our experimental results show that individuals with lower time discount factors are more prone to suffer pain in advance. We provide a framework to rationalize the connection between pain anticipation and impatience. in this set up, more impatient subjects, who only value very near events, mainly take into account the present negative effects of medical procedures (the costs, whereas more patient individuals have a net positive valuation of medical events, given that they are able to value both the cost incurred now and all the benefits to be accrued in the future.

    Este artículo trata de la anticipación del dolor experimentada antes de los procedimientos médicos. nuestros resultados experimentales muestran que los individuos con factor de descuento temporal más bajo son más proclives a sufrir dolor por adelantado. el artículo proporciona un marco en el que racionalizar la relación existente entre impaciencia y anticipación del dolor. en este marco, los sujetos más impacientes, que evalúan sólo los eventos muy próximos en el tiempo, focalizan su atención principalmente en los efectos negativos de los procedimientos médicos (sólo los costes, mientras que los individuos más pacientes tienen una valoración neta positiva de los actos médicos puesto que valoran tanto el coste en el que se incurre en el presente como los beneficios que se obtendrán en el futuro.

  1. Attitudes toward Seeking Professional Help for an Eating Disorder: The Role of Stigma and Anticipated Outcomes

    Hackler, Ashley H.; Vogel, David L.; Wade, Nathaniel G.

    2010-01-01

    This study examined the relationship between self-stigma, anticipated risks and benefits associated with seeking counseling, and attitudes toward seeking counseling among college students with disordered eating attitudes and behaviors. The results of hierarchical regression analyses demonstrated that self-stigma and the anticipated risks and…

  2. Manche centre

    1997-05-01

    After a general presentation of radioactivity and radioactive wastes and of the French national agency for the management of radioactive wastes (ANDRA), this brochure gives a general overview of the Manche low- and medium-level radioactive waste disposal centre: principles of storage safety, waste containers (first confinement barrier), storage facility and cover (second confinement barrier), the underground (third confinement barrier), the impact of the centre on its environment, and the control of radioactivity in the vicinity of the centre. (J.S.)

  3. CANDU 9 Control Centre Mockup

    Webster, A.; Macbeth, M.J.

    1996-01-01

    This paper provides a summary of the design process being followed, the benefits of applying a systematic design using human factors engineering, presents an overview of the CANDU 9 control centre mockup facility, illustrates the control centre mockup with photographs of the 3D CADD model and the full scale mockup, and provides an update on the current status of the project. (author)

  4. Anticipated consumer reaction to irradiated foods

    Young, M.

    1983-01-01

    The reaction on first hearing of food irradiation is horror, revulsion, and disbelief that we could seriously anticipate such a thing. Ignorance coupled with fear of anything to do with the nuclear industry is the reason for such extreme reaction. Before anyone rushes into marketing irradiated foods, a lot of careful preparation must be done. A consumer education program is essential. The consumers must be told why it is proposed to irradiate food, what benefits it will bring to the public. Enough need will have to be demonstrated to overcome the supposed risk factor. Symbol on all irradiated foods must not be used to alert or alarm the consumer but rather as a piece of information. It will be necessary to be ever vigilant, to keep up the diligent training of food irradiators, food handlers and food inspectors. Irradiation is not a substitute for good manufacturing practice. So by using a different name or symbol, irradiated foods will soon be a part of our lives

  5. Anticipating urgent surgery in operating room departments

    van der Lans, M.; Hans, Elias W.; Hurink, Johann L.; Wullink, Gerhard; van Houdenhoven, M.; Kazemier, G.

    2005-01-01

    Operating Room (OR) departments need to create robust surgical schedules that anticipate urgent surgery, while minimizing urgent surgery waiting time and overtime, and maximizing utilization. We consider two levels of planning and control to anticipate urgent surgery. At the tactical level, we study

  6. Overlapping neural systems represent cognitive effort and reward anticipation.

    Vassena, Eliana; Silvetti, Massimo; Boehler, Carsten N; Achten, Eric; Fias, Wim; Verguts, Tom

    2014-01-01

    Anticipating a potential benefit and how difficult it will be to obtain it are valuable skills in a constantly changing environment. In the human brain, the anticipation of reward is encoded by the Anterior Cingulate Cortex (ACC) and Striatum. Naturally, potential rewards have an incentive quality, resulting in a motivational effect improving performance. Recently it has been proposed that an upcoming task requiring effort induces a similar anticipation mechanism as reward, relying on the same cortico-limbic network. However, this overlapping anticipatory activity for reward and effort has only been investigated in a perceptual task. Whether this generalizes to high-level cognitive tasks remains to be investigated. To this end, an fMRI experiment was designed to investigate anticipation of reward and effort in cognitive tasks. A mental arithmetic task was implemented, manipulating effort (difficulty), reward, and delay in reward delivery to control for temporal confounds. The goal was to test for the motivational effect induced by the expectation of bigger reward and higher effort. The results showed that the activation elicited by an upcoming difficult task overlapped with higher reward prospect in the ACC and in the striatum, thus highlighting a pivotal role of this circuit in sustaining motivated behavior.

  7. Role for Genetic Anticipation in Lynch Syndrome

    Nilbert, Mef; Timshel, Susanne; Bernstein, Inge

    2009-01-01

    PURPOSE: Anticipation (ie, an earlier age at onset in successive generations) is linked to repeat expansion in neurodegenerative syndromes, whereas its role in hereditary cancer is unclear. We assessed anticipation in Lynch syndrome (hereditary nonpolyposis colorectal cancer [HNPCC]), in which DNA...... parent-child pairs in which age at the first cancer diagnosis was assessed. A paired t-test and a specifically developed bivariate model were used to assess a possible role of anticipation. RESULTS: Both methods revealed anticipation with children developing cancer mean 9.8 years (P ... parents using the paired t-test and 5.5 years (P anticipation with 7.2 years earlier age at onset was identified also in the oldest cohort, in which the children were observed until they were older than 80 years...

  8. Benefits of being biased!

    Administrator

    Journal of Genetics, Vol. 83, No. 2, August 2004. Keywords. codon bias; alcohol dehydrogenase; Darwinian ... RESEARCH COMMENTARY. Benefits of being biased! SUTIRTH DEY*. Evolutionary Biology Laboratory, Evolutionary & Organismal Biology Unit,. Jawaharlal Nehru Centre for Advanced Scientific Research,.

  9. Anticipating and Resisting the Temptation to Behave Unethically.

    Sheldon, Oliver J; Fishbach, Ayelet

    2015-07-01

    Ethical dilemmas pose a self-control conflict between pursuing immediate benefits through behaving dishonestly and pursuing long-term benefits through acts of honesty. Therefore, factors that facilitate self-control for other types of goals (e.g., health and financial) should also promote ethical behavior. Across four studies, we find support for this possibility. Specifically, we find that only under conditions that facilitate conflict identification--including the consideration of several decisions simultaneously (i.e., a broad decision frame) and perceived high connectedness to the future self--does anticipating a temptation to behave dishonestly in advance promote honesty. We demonstrate these interaction patterns between conflict identification and temptation anticipation in negotiation situations (Study 1), lab tasks (Study 2), and ethical dilemmas in the workplace (Studies 3-4). We conclude that identifying a self-control conflict and anticipating a temptation are two necessary preconditions for ethical decision making. © 2015 by the Society for Personality and Social Psychology, Inc.

  10. Brain Responses during the Anticipation of Dyspnea.

    Stoeckel, M Cornelia; Esser, Roland W; Gamer, Matthias; Büchel, Christian; von Leupoldt, Andreas

    2016-01-01

    Dyspnea is common in many cardiorespiratory diseases. Already the anticipation of this aversive symptom elicits fear in many patients resulting in unfavorable health behaviors such as activity avoidance and sedentary lifestyle. This study investigated brain mechanisms underlying these anticipatory processes. We induced dyspnea using resistive-load breathing in healthy subjects during functional magnetic resonance imaging. Blocks of severe and mild dyspnea alternated, each preceded by anticipation periods. Severe dyspnea activated a network of sensorimotor, cerebellar, and limbic areas. The left insular, parietal opercular, and cerebellar cortices showed increased activation already during dyspnea anticipation. Left insular and parietal opercular cortex showed increased connectivity with right insular and anterior cingulate cortex when severe dyspnea was anticipated, while the cerebellum showed increased connectivity with the amygdala. Notably, insular activation during dyspnea perception was positively correlated with midbrain activation during anticipation. Moreover, anticipatory fear was positively correlated with anticipatory activation in right insular and anterior cingulate cortex. The results demonstrate that dyspnea anticipation activates brain areas involved in dyspnea perception. The involvement of emotion-related areas such as insula, anterior cingulate cortex, and amygdala during dyspnea anticipation most likely reflects anticipatory fear and might underlie the development of unfavorable health behaviors in patients suffering from dyspnea.

  11. David Barker: the revolution that anticipates existence

    Italo Farnetani

    2014-01-01

    Full Text Available David Barker is the man who “anticipated" the existence of babies by focusing attention on the importance of the fetus and what takes place during intrauterine life. Barker was one of the physicians who in the last decades brought about the greatest changes in medicine, changes so important as to represent a veritable revolution in medical thought. According to Barker's studies, the embryo obviously has a genetic complement coming from the mother and father, but from the very first stages of development it begins to undergo the influence of the outside environment, just as occurs for adults whose biological, psychological and pathological aspects are influenced by the environment to a not well-established percentage between genetic complement and epigenetics. Much of our future lives as adults is decided in our mothers' wombs. If Barker's discovery was revolutionary from the cultural standpoint, it was even more so from the strictly medical one. Barker's research method was rigid from the methodological standpoint, but innovative and speculative in its working hypotheses, with a humanistic slant. Barker's idea has another practical corollary: it is evident that the role of obstetricians, perinatologists and neonatologists is more and more relevant in medicine and future prevention. Unquestionably, besides the enormous merits of his clinical research, among the benefits that Barker has contributed there is that of having helped us to see things from new points of view. Not only is the neonate (and even more so the fetus not an adult of reduced proportions, but perhaps the neonate is the "father" of the adult person.

  12. Anticipated ethical challenges with growing molecular prenatal ...

    Anticipated ethical challenges with growing molecular prenatal diagnosis in Nigeria. ... Bayero Journal of Pure and Applied Sciences ... Ethical standards in medical laboratories are derived from medical ethics therefore, the four fundamental ...

  13. Anticipation Behavior Upstream of a Bottleneck

    Duives, D.C.; Daamen, W.; Hoogendoorn, S.P.

    2014-01-01

    Whether pedestrian movements do or do not follow similar patterns as vehicular traffic while experiencing congestion is not entirely understood. Using data gathered during bottleneck experiments under laboratory conditions, the phenomenon of anticipation before entering congestion is studied. This

  14. Seeing Like a Tesla: How Can We Anticipate Self-Driving Worlds?

    Jack Stilgoe

    2018-02-01

    Full Text Available In the last five years, investment and innovation in self-driving cars has accelerated dramatically. Automotive autonomy, once seen as impossible, is now sold as inevitable. Much of the governance discussion has centred on risk: will the cars be safer than their human-controlled counterparts? As with conventional cars, harder long-term questions relate to the future worlds that self-driving technologies might enable or even demand. The vision of an autonomous vehicle – able to navigate the world’s complexity using only its sensors and processors – on offer from companies like Tesla is intentionally misleading. So-called “autonomous” vehicles will depend upon webs of social and technical connectivity. For their purported benefits to be realised, infrastructures that were designed around humans will need to be upgraded in order to become machine-readable. It is vital to anticipate the politics of self-driving worlds in order to avoid exacerbating the inequalities that have emerged around conventional cars. Rather than being dazzled by the Tesla view, policymakers should start seeing like a city, from multiple perspectives. Good governance for self-driving cars means democratising experimentation and creating genuine collaboration between companies and local governments.

  15. Anticipating and projective-anticipating synchronization of coupled multidelay feedback systems

    Hoang, Thang Manh; Nakagawa, Masahiro

    2007-01-01

    In this Letter, the model of coupled multidelay feedback systems is investigated with the schemes of anticipating and projective-anticipating synchronizations. Under these synchronization schemes, the slave anticipates the master's trajectory. Moreover, with projective-anticipating synchronization there exists a scale factor in the amplitudes of the master's and slave's state variables. In the both cases, the driving signals are in the form of multiple nonlinear transformations of delayed state variable. The Krasovskii-Lyapunov theory is used to consider the sufficient condition for synchronization. The effectiveness of the proposed schemes is confirmed by the numerical simulation of specific examples with modified Ikeda and Mackey-Glass systems

  16. Fuel cycle centres

    Hagen, M.

    1977-01-01

    The concept of co-locating and integrating fuel cycle facilities at one site is discussed. This concept offers considerable advantages, especially in minimizing the amount of radioactive material to be transported on public roads. Safeguards and physical protection as relating to such an integrated system of facilities are analysed in detail, also industrial and commercial questions. An overall risk-benefit evaluation turns out to be in favour of fuel cycle centres. These centres seem to be specifically attractive with regard to the back end of the fuel cycle, including on-site disposal of radioactive wastes. The respective German approach is presented as an example. Special emphasis is given to the site selection procedures in this case. Time scale and cost for the implementation of this concept are important factors to be looked at. Since participation of governmental institutions in these centres seems to be indispensable their respective roles as compared to industry must be clearly defined. The idea of adjusting fuel cycle centres to regional rather than national use might be an attractive option, depending on the specific parameters in the region, though results of existing multinational ventures are inconclusive in this respect. Major difficulties might be expected e.g. because of different national safety regulations and standards as well as commercial conditions among partner countries. Public acceptance in the host country seems to be another stumbling block for the realization of this type of multinational facilities

  17. Anticipation in Soccer: A Systematic Review

    Gonçalves Eder

    2015-06-01

    Full Text Available Purpose. The present study aimed to examine the current methods employed to assess anticipation in soccer players as well as to elicit the main findings of recent studies. Methods. The study was carried out in systematic review form and its sample comprised nine scientific papers published in academic journals. Only the studies involving soccer players (professionals and amateurs, except goalkeepers were included in this review. Results and conclusions. We observed that most of the studies employed video footage obtained from soccer matches, which are occluded at a given point for study participants to quickly and precisely elicit the positions of opponents, teammates and the ball as well as anticipate actions (dribbling, shooting, passing from surrounding players (teammates and opponents. In addition, the studies compared the performance of players from both high and low competitive levels in anticipation tasks.

  18. Role for Genetic Anticipation in Lynch Syndrome

    Nilbert, Mef; Timshel, Susanne; Bernstein, Inge

    2009-01-01

    PURPOSE: Anticipation (ie, an earlier age at onset in successive generations) is linked to repeat expansion in neurodegenerative syndromes, whereas its role in hereditary cancer is unclear. We assessed anticipation in Lynch syndrome (hereditary nonpolyposis colorectal cancer [HNPCC]), in which DNA...... mismatch repair (MMR) defects cause early and accelerated tumor development with a broad tumor spectrum. PATIENTS AND METHODS: In the population-based Danish HNPCC registry, 407 MMR gene mutation carriers who had developed cancer associated with Lynch syndrome, were identified. These individuals formed 290....... The effect remained when cancers diagnosed at surveillance were excluded, applied to maternal as well as paternal inheritance, and was independent of the MMR gene mutated. CONCLUSION: The effect from anticipation demonstrated in this large, population-based Lynch syndrome cohort underscores the need...

  19. Could Intelligent Tutors Anticipate Successfully User Reactions?

    Kalisz, Eugenia; Florea, Adina Magda

    2006-06-01

    Emotions have been shown to have an important impact on several human processes such as decision-making, planning, cognition, and learning. In an e-learning system, an artificial tutor capable of effectively understanding and anticipating the student emotions during learning will have a significantly enhanced role. The paper presents a model of an artificial tutor endowed with synthesized emotions according to the BDE model, previously developed by the authors. It also analyzes possible student reactions while interacting with the learning material and the way the artificial tutor could anticipate and should respond to these reactions, with adequate actions.

  20. Anticipation: learning from the past. The Russian/Soviet contributions to the science of anticipation

    Bazac, Ana

    2018-05-01

    The focus on Russian/Soviet contributions is only an opportunity to understand the objective premises of anticipation. Since anticipation expresses a main concept characterizing human action, it is important to see whether and how it corresponds to the neuro-physiology of the human. The aim of this review is to show that anticipation is neuro-physiologically constitutive and is intertwined with all other reflective, cognitive, and coordinative functions that form an inseparable unity in the process of adaptation. The experiments described in the book draw attention to anticipation as the internal tendency of the living that cannot be ignored. The review highlights the dialectic of continuity and discontinuity in the living from the standpoint of anticipation, and the holistic conclusions of the scientific research regarding the living and the human being.

  1. Learning from anticipated and abnormal plant transients

    Varnado, B.

    1983-01-01

    A report is given of the American Nuclear Society topical meeting on Anticipated and Abnormal Transients in Light Water Reactors held in Jackson, Wyoming in September 1983. Industry involvement in the evaluation of operating experience, human error contributions, transient management, thermal hydraulic modelling, the role of probabilistic risk assessment and the cost of transient incidents are discussed. (U.K.)

  2. Anticipating ethical issues in emerging IT

    Brey, Philip A.E.

    2012-01-01

    In this essay, a new approach to the ethics of emerging information technology will be presented, called anticipatory technology ethics (ATE). The ethics of emerging technology is the study of ethical issues at the R&D and introduction stage of technology development through anticipation of possible

  3. Impact of anticipation in dynamical systems

    Gerlee, P.; Tunstrøm, K.; Lundh, T.; Wennberg, B.

    2017-12-01

    Many animals, including humans, have predictive capabilities and, presumably, base their behavioral decisions—at least partially—upon an anticipated state of their environment. We explore a minimal version of this idea in the context of particles that interact according to a pairwise potential. Anticipation enters the picture by calculating the interparticle forces from linear extrapolations of the particle positions some time τ in the future. Simulations show that for intermediate values of τ , compared to a transient time scale defined by the potential and the initial conditions, the particles form rotating clusters in which the particles are arranged in a hexagonal pattern. Analysis of the system shows that anticipation induces energy dissipation and we show that the kinetic energy asymptotically decays as 1 /t . Furthermore, we show that the angular momentum is not necessarily conserved for τ >0 , and that asymmetries in the initial condition therefore can cause rotational movement. These results suggest that anticipation could play an important role in collective behavior, since it may induce pattern formation and stabilizes the dynamics of the system.

  4. Well-being and Anticipation for Future Positive Events: Evidences from an fMRI Study.

    Luo, Yangmei; Chen, Xuhai; Qi, Senqing; You, Xuqun; Huang, Xiting

    2017-01-01

    Anticipation for future confers great benefits to human well-being and mental health. However, previous work focus on how people's well-being correlate with brain activities during perception of emotional stimuli, rather than anticipation for the future events. Here, the current study investigated how well-being relates to neural circuitry underlying the anticipating process of future desired events. Using event-related functional magnetic resonance imaging, 40 participants were scanned while they were performing an emotion anticipation task, in which they were instructed to anticipate the positive or neutral events. The results showed that bilateral medial prefrontal cortex (MPFC) were activated during anticipation for positive events relative to neutral events, and the enhanced brain activation in MPFC was associated with higher level of well-being. The findings suggest a neural mechanism by which the anticipation process to future desired events correlates to human well-being, which provide a future-oriented view on the neural sources of well-being.

  5. From Discrimination to Internalized Mental Illness Stigma: The Mediating Roles of Anticipated Discrimination and Anticipated Stigma

    Quinn, Diane M.; Williams, Michelle K.; Weisz, Bradley M.

    2015-01-01

    Objective Internalizing mental illness stigma is related to poorer well-being, but less is known about the factors that predict levels of internalized stigma. This study explored how experiences of discrimination relate to greater anticipation of discrimination and devaluation in the future, and how anticipation of stigma, in turn predicts greater stigma internalization. Method Participants were 105 adults with mental illness who self-reported their experiences of discrimination based on their mental illness, their anticipation of discrimination and social devaluation from others in the future, and their level of internalized stigma. Participants were approached in several locations and completed surveys on laptop computers. Results Correlational analyses indicated that more experiences of discrimination due to one’s mental illness were related to increased anticipated discrimination in the future, increased anticipated social stigma from others, and greater internalized stigma. Multiple serial mediator analyses showed that the effect of experiences of discrimination on internalized stigma was fully mediated by increased anticipated discrimination and anticipated stigma. Conclusion and Implications for Practice Experiences of discrimination over the lifetime may influence not only how much future discrimination people with mental illness are concerned with but also how much they internalize negative feelings about the self. Mental health professionals may need to address concerns with future discrimination and devaluation in order to decrease internalized stigma. PMID:25844910

  6. From discrimination to internalized mental illness stigma: The mediating roles of anticipated discrimination and anticipated stigma.

    Quinn, Diane M; Williams, Michelle K; Weisz, Bradley M

    2015-06-01

    Internalizing mental illness stigma is related to poorer well-being, but less is known about the factors that predict levels of internalized stigma. This study explored how experiences of discrimination relate to greater anticipation of discrimination and devaluation in the future and how anticipation of stigma in turn predicts greater stigma internalization. Participants were 105 adults with mental illness who self-reported their experiences of discrimination based on their mental illness, their anticipation of discrimination and social devaluation from others in the future, and their level of internalized stigma. Participants were approached in several locations and completed surveys on laptop computers. Correlational analyses indicated that more experiences of discrimination due to one's mental illness were related to increased anticipated discrimination in the future, increased anticipated social stigma from others, and greater internalized stigma. Multiple serial mediator analyses showed that the effect of experiences of discrimination on internalized stigma was fully mediated by increased anticipated discrimination and anticipated stigma. Experiences of discrimination over one's lifetime may influence not only how much future discrimination people with mental illness are concerned with but also how much they internalize negative feelings about the self. Mental health professionals may need to address concerns with future discrimination and devaluation in order to decrease internalized stigma. (c) 2015 APA, all rights reserved).

  7. Genetic anticipation in Swedish Lynch syndrome families.

    Jenny von Salomé

    2017-10-01

    Full Text Available Among hereditary colorectal cancer predisposing syndromes, Lynch syndrome (LS caused by mutations in DNA mismatch repair genes MLH1, MSH2, MSH6 or PMS2 is the most common. Patients with LS have an increased risk of early onset colon and endometrial cancer, but also other tumors that generally have an earlier onset compared to the general population. However, age at first primary cancer varies within families and genetic anticipation, i.e. decreasing age at onset in successive generations, has been suggested in LS. Anticipation is a well-known phenomenon in e.g neurodegenerative diseases and several reports have studied anticipation in heritable cancer. The purpose of this study is to determine whether anticipation can be shown in a nationwide cohort of Swedish LS families referred to the regional departments of clinical genetics in Lund, Stockholm, Linköping, Uppsala and Umeå between the years 1990-2013. We analyzed a homogenous group of mutation carriers, utilizing information from both affected and non-affected family members. In total, 239 families with a mismatch repair gene mutation (96 MLH1 families, 90 MSH2 families including one family with an EPCAM-MSH2 deletion, 39 MSH6 families, 12 PMS2 families, and 2 MLH1+PMS2 families comprising 1028 at-risk carriers were identified among the Swedish LS families, of which 1003 mutation carriers had available follow-up information and could be included in the study. Using a normal random effects model (NREM we estimate a 2.1 year decrease in age of diagnosis per generation. An alternative analysis using a mixed-effects Cox proportional hazards model (COX-R estimates a hazard ratio of exp(0.171, or about 1.19, for age of diagnosis between consecutive generations. LS-associated gene-specific anticipation effects are evident for MSH2 (2.6 years/generation for NREM and hazard ratio of 1.33 for COX-R and PMS2 (7.3 years/generation and hazard ratio of 1.86. The estimated anticipation effects for MLH1

  8. Genetic anticipation in Swedish Lynch syndrome families.

    von Salomé, Jenny; Boonstra, Philip S; Karimi, Masoud; Silander, Gustav; Stenmark-Askmalm, Marie; Gebre-Medhin, Samuel; Aravidis, Christos; Nilbert, Mef; Lindblom, Annika; Lagerstedt-Robinson, Kristina

    2017-10-01

    Among hereditary colorectal cancer predisposing syndromes, Lynch syndrome (LS) caused by mutations in DNA mismatch repair genes MLH1, MSH2, MSH6 or PMS2 is the most common. Patients with LS have an increased risk of early onset colon and endometrial cancer, but also other tumors that generally have an earlier onset compared to the general population. However, age at first primary cancer varies within families and genetic anticipation, i.e. decreasing age at onset in successive generations, has been suggested in LS. Anticipation is a well-known phenomenon in e.g neurodegenerative diseases and several reports have studied anticipation in heritable cancer. The purpose of this study is to determine whether anticipation can be shown in a nationwide cohort of Swedish LS families referred to the regional departments of clinical genetics in Lund, Stockholm, Linköping, Uppsala and Umeå between the years 1990-2013. We analyzed a homogenous group of mutation carriers, utilizing information from both affected and non-affected family members. In total, 239 families with a mismatch repair gene mutation (96 MLH1 families, 90 MSH2 families including one family with an EPCAM-MSH2 deletion, 39 MSH6 families, 12 PMS2 families, and 2 MLH1+PMS2 families) comprising 1028 at-risk carriers were identified among the Swedish LS families, of which 1003 mutation carriers had available follow-up information and could be included in the study. Using a normal random effects model (NREM) we estimate a 2.1 year decrease in age of diagnosis per generation. An alternative analysis using a mixed-effects Cox proportional hazards model (COX-R) estimates a hazard ratio of exp(0.171), or about 1.19, for age of diagnosis between consecutive generations. LS-associated gene-specific anticipation effects are evident for MSH2 (2.6 years/generation for NREM and hazard ratio of 1.33 for COX-R) and PMS2 (7.3 years/generation and hazard ratio of 1.86). The estimated anticipation effects for MLH1 and MSH6 are

  9. Genetic anticipation in Swedish Lynch syndrome families

    von Salomé, Jenny; Boonstra, Philip S.; Karimi, Masoud; Silander, Gustav; Stenmark-Askmalm, Marie; Gebre-Medhin, Samuel; Aravidis, Christos; Nilbert, Mef; Lindblom, Annika; Lagerstedt-Robinson, Kristina

    2017-01-01

    Among hereditary colorectal cancer predisposing syndromes, Lynch syndrome (LS) caused by mutations in DNA mismatch repair genes MLH1, MSH2, MSH6 or PMS2 is the most common. Patients with LS have an increased risk of early onset colon and endometrial cancer, but also other tumors that generally have an earlier onset compared to the general population. However, age at first primary cancer varies within families and genetic anticipation, i.e. decreasing age at onset in successive generations, ha...

  10. Partial observation control in an anticipating environment

    Oeksendal, B; Sulem, A

    2004-01-01

    A study is made of a controlled stochastic system whose state X(t) at time t is described by a stochastic differential equation driven by Levy processes with filtration {F t } telementof[0,T] . The system is assumed to be anticipating, in the sense that the coefficients are assumed to be adapted to a filtration {G t } t≥0 with F t subset of equal G t for all t element of [0,T]. The corresponding anticipating stochastic differential equation is interpreted in the sense of forward integrals, which naturally generalize semimartingale integrals. The admissible controls are assumed to be adapted to a filtration {E t } telementof[0,T] such that E t subset of equal F t for all t element of [0,T]. The general problem is to maximize a given performance functional of this system over all admissible controls. This is a partial observation stochastic control problem in an anticipating environment. Examples of applications include stochastic volatity models in finance, insider influenced financial markets, and stochastic control of systems with delayed noise effects. Some particular cases in finance, involving optimal portfolios with logarithmic utility, are solved explicitly

  11. Anticipation in Law and Social Science

    Winston P. Nagan

    2017-06-01

    Full Text Available This article explores a particular aspect of the role of anticipation in social and legal processes. The program begins by recognizing that social interaction happens within a time-space manifold of events. This means that society functions in terms of events located on the plane of time and the situation of space. This means that social process is a dynamic. As an ancient philosopher put it, change is so ubiquitous that you cannot jump into the same river twice. Since we tend to look at social dynamics in a more static way, one major theorist reminds us that the stable in social process is a special case of the unstable. The article underscores a point that the anticipatory perspective is a ubiquitous part of social dynamics and change. Indeed, it is a critical component of social coexistence. To briefly illustrate, if the members of a governing group come into power, they will immediately have to anticipate the security needs, the economic needs, the educational needs, the health and well-being needs, the skill and labor needs, the food needs of the body politic, the requirements of effective family relationships, the requirements of morality and ethics and the needs of aesthetics. The paper provides a framework in which anticipation is used to predict the problems that emerge from the social process. The value of a social science that facilitates anticipation before problems occur provides opportunities on the time-space manifold of society to develop problem-solving strategies with a better chance of those strategies being successful. To utilize this approach, the authors provide the sophisticated model of social process developed by WAAS Fellows Lasswell and McDougal: Human beings pursue values through institutions based on resources. Using this model the authors provide a provisional map of the social process with key markers at points likely to generate important problems. The markers in the maps are as follows: participators

  12. Responses of adults who stutter to the anticipation of stuttering.

    Jackson, Eric S; Yaruss, J Scott; Quesal, Robert W; Terranova, Valerie; Whalen, D H

    2015-09-01

    Many people who stutter experience the phenomenon of anticipation-the sense that stuttering will occur before it is physically and overtly realized. A systematic investigation of how people who stutter respond to anticipation has not been previously reported. The purposes of this study were to provide self-report evidence of what people do in response to anticipation of stuttering and to determine the extent to which this anticipation occurs. Thirty adults who stutter indicated on a Likert rating scale the extent to which they anticipate stuttering and answered three open-ended (written) questions regarding how they respond to anticipation. All participants reported experiencing anticipation at least "sometimes," and 77% of the participants reported experiencing anticipation "often" or "always." The extent to which participants reported experiencing anticipation was not related to stuttering severity, impact, or treatment history. Analysis of written responses revealed 24 major categories, which were heuristically divided into action or non-action responses. Categories representing avoidance and self-management strategies were further divided into 14 and 19 subcategories, respectively. Participants were just as likely to view anticipation as helpful as they were to view it as harmful. Findings demonstrate that most, if not all, adults who stutter experience anticipation, and the majority of adults who stutter report doing so at least often. Adults who stutter respond to this anticipation by altering the speech production process in various ways. Results highlight the importance of the role that anticipation plays in how stuttering behaviors manifest themselves. The reader will be able to: (a) summarize existing literature on the anticipation of stuttering; (b) describe the role and extent of anticipation of stuttering in adults; (c) describe the various ways that adults who stutter respond to anticipation; (d) describe the importance of measuring anticipation in

  13. Anticipation learning from the past the Russian/Soviet contributions to the science of anticipation

    2015-01-01

    This volume presents the work of leading scientists from Russia, Georgia, Estonia, Lithuania, Israel, and the USA, revealing major insights long unknown to the scientific community. Without any doubt their work will provide a springboard for further research in anticipation. Until recently, Robert Rosen (Anticipatory Systems) and Mihai Nadin (MIND – Anticipation and Chaos) were deemed forerunners in this still new knowledge domain. The distinguished neurobiologist, Steven Rose, pointed to the fact that Soviet neuropsychological theories have not on the whole been well received by Western science. These earlier insights as presented in this volume make an important contribution to the foundation of the science of anticipation. It is shown that the daring hypotheses and rich experimental evidence produced by Bernstein, Beritashvili, Ukhtomsky, Anokhin, and Uznadze, among others—extend foundational work to aspects of neuroscience, physiology, motorics, education.

  14. Anticipated transient without SCRAM experiments at LOFT

    Grush, W.H.; Harvego, E.A.; Koizumi, Y.; Varacalle, D.J.

    1983-01-01

    This paper discusses the experimental results for two anticipated transients without scram (ATWS) experiments, and compares computer code predictions with the experimental data. Experiment L9-3 simulated an ATWS in a commercial pressurized water reactor (PWR) initiated by a complete loss of feedwater and Experiment L9-4 simulated a loss-of-offsite-power-initiated (loss of feedwater and trip of the primary coolant pumps) ATWS. The LOFT facility is uniquely suited for ATWS experiments because it is a volumetrically scaled (1/44) experimental PWR designed to simulate the major components and system responses of larger commercial PWRs during both hypothesized loss-of-coolant accidents and anticipated transients. In both of the examined experiments, the primary system transient behavior was dominated by the interactions between the steam generator primary-to-secondary heat removal, the reactor kinetics, and the relief valve actuation. It is demonstrated that the discussed ATWS events can be controlled by properly sized automatic safety systems

  15. Brain activation during anticipation of sound sequences.

    Leaver, Amber M; Van Lare, Jennifer; Zielinski, Brandon; Halpern, Andrea R; Rauschecker, Josef P

    2009-02-25

    Music consists of sound sequences that require integration over time. As we become familiar with music, associations between notes, melodies, and entire symphonic movements become stronger and more complex. These associations can become so tight that, for example, hearing the end of one album track can elicit a robust image of the upcoming track while anticipating it in total silence. Here, we study this predictive "anticipatory imagery" at various stages throughout learning and investigate activity changes in corresponding neural structures using functional magnetic resonance imaging. Anticipatory imagery (in silence) for highly familiar naturalistic music was accompanied by pronounced activity in rostral prefrontal cortex (PFC) and premotor areas. Examining changes in the neural bases of anticipatory imagery during two stages of learning conditional associations between simple melodies, however, demonstrates the importance of fronto-striatal connections, consistent with a role of the basal ganglia in "training" frontal cortex (Pasupathy and Miller, 2005). Another striking change in neural resources during learning was a shift between caudal PFC earlier to rostral PFC later in learning. Our findings regarding musical anticipation and sound sequence learning are highly compatible with studies of motor sequence learning, suggesting common predictive mechanisms in both domains.

  16. Locomotor Behavior of Chickens Anticipating Incline Walking

    Chantal LeBlanc

    2018-01-01

    Full Text Available Keel bone damage (KBD is prevalent in hens raised for egg production, and ramps between different tiers in aviaries have potential to reduce the frequency of falls resulting in KBD. Effective use of ramps requires modulation of locomotion in anticipation of the incline. Inadequate adaptive locomotion may be one explanation why domestic layer hens (Gallus gallus domesticus exhibit high rates of KBD. To improve understanding of the capacity of hens to modulate their locomotion in anticipation of climbing, we measured the effects of incline angle upon the mechanics of the preparatory step before ascending a ramp. Because the energetic challenge of climbing increases with slope, we predicted that as angle of incline increased, birds during foot contact with the ground before starting to climb would increase their peak force and duration of contact and reduce variation in center of pressure (COP under their foot. We tested 20 female domestic chickens on ramp inclines at slopes of +0°, +40°, and +70° when birds were 17, 21, 26, 31, and 36 weeks of age. There were significantly higher vertical peak ground reaction forces in preparation at the steepest slope, and ground contact time increased significantly with each increase in ramp angle. Effects upon variation in COP were not apparent; likewise, effects of limb length, age, body mass were not significant. Our results reveal that domestic chickens are capable of modulating their locomotion in response to incline angle.

  17. Anticipation: Beyond synthetic biology and cognitive robotics.

    Nasuto, Slawomir J; Hayashi, Yoshikatsu

    2016-10-01

    The aim of this paper is to propose that current robotic technologies cannot have intentional states any more than is feasible within the sensorimotor variant of embodied cognition. It argues that anticipation is an emerging concept that can provide a bridge between both the deepest philosophical theories about the nature of life and cognition and the empirical biological and cognitive sciences steeped in reductionist and Newtonian conceptions of causality. The paper advocates that in order to move forward, cognitive robotics needs to embrace new platforms and a conceptual framework that will enable it to pursue, in a meaningful way, questions about autonomy and purposeful behaviour. We suggest that hybrid systems, part robotic and part cultures of neurones, offer experimental platforms where different dimensions of enactivism (sensorimotor, constitutive foundations of biological autonomy, including anticipation), and their relative contributions to cognition, can be investigated in an integrated way. A careful progression, mindful to the deep philosophical concerns but also respecting empirical evidence, will ultimately lead towards unifying theoretical and empirical biological sciences and may offer advancement where reductionist sciences have been so far faltering. Copyright © 2016 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

  18. Senior Benefits

    Information Medicaid Public Health Centers Temporary "Cash" Assistance Senior Benefits Program GovDelivery Skip Navigation Links Health and Social Services > Public Assistance > Senior Benefits Page Content Senior Benefits Senior Benefits Logo Senior Benefits Fact Sheet - June, 2016 Reduction Information

  19. 12 CFR 313.140 - Future benefits.

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Future benefits. 313.140 Section 313.140 Banks... CORPORATE DEBT COLLECTION Civil Service Retirement and Disability Fund Offset § 313.140 Future benefits. Unless otherwise prohibited by law, the FDIC may request that a debtor's anticipated or future benefit...

  20. Five-Year-Old Preschoolers’ Sharing is Influenced by Anticipated Reciprocation

    Xiong, Mingrui; Jiannong, Shi; Wu, Zhen

    2016-01-01

    Whether children share in anticipation of future benefits returned by a partner is an interesting question. In this study, 5-year-old children and an adult partner played a sharing game, in which children donated first and the partner donated afterward. In Experiment 1, the partner’s resources were......-value condition. We found that children were more generous when the partner’s resources were valued higher. These findings demonstrate that 5-year-old preschoolers’ sharing choices take into account the anticipated reciprocity of the recipient, suggesting either self-interested tactical sharing or direct...

  1. Anticipated Activities in Maritime Work, Process Control, and Business Processes

    Andersen, Peter Bøgh

    2004-01-01

    Most activities are anticipated before they are executed. The paper presents methods for describing this anticipated state and the processes that may lead to a new state where the activities are executed. The method builds on linguistic case-theory.......Most activities are anticipated before they are executed. The paper presents methods for describing this anticipated state and the processes that may lead to a new state where the activities are executed. The method builds on linguistic case-theory....

  2. Attitudes towards aloneness during adolescence : A Person-Centred Approach

    Teppers, E.; Luyckx, K.; Vanhalst, J.; Klimstra, T.A.; Goossens, L.

    2014-01-01

    Benefits and disadvantages of solitude for adolescents are often highlighted. However, research focusing on adolescents' attitudes towards solitude and their associations with such disadvantages or benefits is rather limited. The present study provides a person-centred perspective on the

  3. Intent, Future, Anticipation: A Semiotic, Transdisciplinary Approach

    Loeckenhoff, Hellmut

    2008-10-01

    Encouraged e.g. by chaos theory and (bio-)semiotics science is trying to attempt a deeper understanding of life. The paradigms of physics alone prove not sufficient to explain f. ex. evolution or phylogenesis and ontogenesis. In complement, research on life systems reassesses paradigmatic models not only for living systems and not only on the strict biological level. The ontological as well as the epistemological base of science in toto is to be reconsidered. Science itself proves a historical and cultural phenomenon and can be seen as shaped by evolution and semiosis. -Living systems are signified by purpose, intent and, necessarily, by the faculty to anticipate e.g. the cyclic changes of their environment. To understand the concepts behind a proposal is developed towards a model set constituting a transdisciplinary approach. It rests e.g. on concepts of systems, evolution, complexity and semiodynamics.

  4. EP1000 anticipated transient without scram analyses

    Saiu, G.; Frogheri, M.; Schulz, T.L.

    2001-01-01

    The present paper summarizes the main results of the Anticipated Transient Without Scram (ATWS) analysis activity, performed for the European Passive Plant Program (EPP). The behavior of the EP1000 plant following an ATWS has been analyzed by means of the RELAP5/Mod3.2 code. An ATWS is defined as an Anticipated Transient accompanied by a common mode failure in the reactor protection system, such that the control rods do not scram as required to mitigate the consequences of the transient. According to the experience gained in PWR design, the limiting ATWS events, in a PWR, have been found to be the heatup transients caused by a reduction of heat removal capability by the secondary side of the plant. For this reason, the Loss of Normal Feedwater initiating event, to which the failure of the reactor scram is associated, has been analyzed. The purpose of the study is to verify the performance requirements set for the core feedback characteristics (that is to evaluate the effect of the low boron core neutron kinetic parameters), the overpressure protection system, and boration systems to cope with the EUR Acceptance Criteria for ATWS. Another purpose of this analysis was to support development of revised PSA success criteria that would reduce the contribution of ATWS to the large release frequency (LRF). The low boron core improved the basic EP1000 response to an ATWS event. In particular, the peak pressure was significantly lower than that which would result from a standard core configuration. The improved ATWS analysis results also permitted improved ATWS PSA success criteria. For example, the reduced peak pressure allows the use of other plant features to mitigate the event, including manual initiation of feed-bleed cooling in the event of PRHR HX failure. As a result, the core melt frequency and especially the LRF are significantly reduced. (author)

  5. Anticipated Guilt for Not Helping and Anticipated Warm Glow for Helping Are Differently Impacted by Personal Responsibility to Help

    Erlandsson, Arvid; Jungstrand, Amanda Å.; Västfjäll, Daniel

    2016-01-01

    One important motivation for people behaving prosocially is that they want to avoid negative and obtain positive emotions. In the prosocial behavior literature however, the motivations to avoid negative emotions (e.g., guilt) and to approach positive emotions (e.g., warm glow) are rarely separated, and sometimes even aggregated into a single mood-management construct. The aim of this study was to investigate whether anticipated guilt if not helping and anticipated warm glow if helping are influenced similarly or differently when varying situational factors related to personal responsibility to help. Helping scenarios were created and pilot tests established that each helping scenario could be formulated both in a high-responsibility version and in a low-responsibility version. In Study 1 participants read high-responsibility and low-responsibility helping scenarios, and rated either their anticipated guilt if not helping or their anticipated warm glow if helping (i.e., separate evaluation). Study 2 was similar but here participants rated both their anticipated guilt if not helping and their anticipated warm glow if helping (i.e., joint evaluation). Anticipated guilt was clearly higher in the high-responsibility versions, but anticipated warm glow was unaffected (in Studies 1a and 1b), or even higher in the low-responsibility versions (Study 2). In Studies 3 (where anticipated guilt and warm glow were evaluated separately) and 4 (where they were evaluated jointly), personal responsibility to help was manipulated within-subjects. Anticipated guilt was again constantly higher in the high-responsibility versions but for many types of responsibility-manipulations, anticipated warm glow was higher in the low-responsibility versions. The results suggest that we anticipate guilt if not fulfilling our responsibility but that we anticipate warm glow primarily when doing over and beyond our responsibility. We argue that future studies investigating motivations for helping

  6. Anticipated and experienced emotions in environmental risk perception

    Gisela Bohm

    2008-01-01

    Full Text Available Affective forecasting with respect to two environmental risks (ozone depletion, air pollution was investigated by studying tourists who travelled to either Australia or Bangkok and were thus confronted with one of these risks. We measured anticipated outcome and anticipated emotions before the journey, actually experienced outcome and actually experienced emotions during the journey, and anticipated outcome and emotions concerning a future encounter with the same risk after the journey. Results indicate that tourists underestimate (air pollution or correctly predict (ozone depletion both the seriousness of the outcome and their emotional reactions. The relationship between actual outcome and actual emotions is stronger than that between anticipated outcome and anticipated emotions. Furthermore, tourists learn from their travel experience and adjust their anticipations concerning future encounters with the environmental risk. Findings suggest that the domain of environmental risks differs from personal outcomes with respect to the process of affective forecasting.

  7. Anticipated regret and health behavior: A meta-analysis.

    Brewer, Noel T; DeFrank, Jessica T; Gilkey, Melissa B

    2016-11-01

    Risk beliefs are central to most theories of health behavior, yet many unanswered questions remain about an increasingly studied risk construct, anticipated regret. The authors sought to better understand anticipated regret's role in motivating health behaviors. The authors systematically searched electronic databases for studies of anticipated regret and behavioral intentions or health behavior. They used random effects meta-analysis to synthesize effect sizes from 81 studies (n = 45,618). Anticipated regret was associated with both intentions (r+ = .50, p emotions and risk appraisals. Anticipated inaction regret has a stronger and more stable association with health behavior than previously thought. The field should give greater attention to understanding how anticipated regret differs from similar constructs, its role in health behavior theory, and its potential use in health behavior interventions. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  8. ICT AND NIGERIAN BANKS REFORMS: ANALYSIS OF ANTICIPATED IMPACTS IN SELECTED BANKS

    Osabuohien Evans S.C

    2008-01-01

    Banking has become highly Information Communication Technology (ICT) based and due to its intersectoral link, is reaping the benefits of technological revolution as evidenced by its application in most of its operations. This study empirical analyzes the anticipated role ICT has in enhancing the operations of selected Nigerian banks in the light of current reforms. Primary data was employed, which was analyzed using cross-tabulations and regression technique built on the framework of technica...

  9. Improving Students' Reading Comprehension in Descriptive Text Through Anticipation Guide

    Nasution, Maya Puspita

    2014-01-01

    This study concerrns with improving students' reading comprehension in descriptive text through anticipation guide.The objective was to investigate improvement of students' reading comprehension by applying anticipation guide. This research was conducted by using action research method. The subject of the study was grade VII students of SMP SWASTA TAMAN HARAPAN MEDAN totalling to 30 students. They were taught reading comprehension by anticipation guide. The instruments for collecting data wer...

  10. Human-centred Governance

    Bason, Christian

    2017-01-01

    Design approaches are now being applied all over the world as a powerful approach to innovating public policies and services. Christian Bason, author of Leading public design: Discovering human-centred governance, argues that by bringing design methods into play, public managers can lead change...... with citizens at the centre, and discover a new model for steering public organisations: human-centred governance....

  11. The Search for Centre

    Nunes, April

    2006-01-01

    This paper acknowledges the importance of a dancer's centre but likewise highlights the problematic nature of the communication of this concept from dance teacher to student. After a brief introduction of orthodox approaches in finding centre, this paper suggests a method of locating centre through the ancient somatic technique.

  12. CMS Centre at CERN

    2007-01-01

    A new "CMS Centre" is being established on the CERN Meyrin site by the CMS collaboration. It will be a focal point for communications, where physicists will work together on data quality monitoring, detector calibration, offline analysis of physics events, and CMS computing operations. Construction of the CMS Centre begins in the historic Proton Synchrotron (PS) control room. The historic Proton Synchrotron (PS) control room, Opened by Niels Bohr in 1960, will be reused by CMS to built its control centre. TThe LHC@FNAL Centre, in operation at Fermilab in the US, will work very closely with the CMS Centre, as well as the CERN Control Centre. (Photo Fermilab)The historic Proton Synchrotron (PS) control room is about to start a new life. Opened by Niels Bohr in 1960, the room will be reused by CMS to built its control centre. When finished, it will resemble the CERN Contro...

  13. Anticipated and abnormal transients in nuclear power plants

    Karam, R.A.

    1987-01-01

    This book contains the proceedings of an international conference on Anticipated and Abnormal Transients in Nuclear Power Plants. Included are the following papers: Comparative evaluation of recent water hammer events in light water reactors, Rick reduction through enhanced human performance, Assessment of the performance of an emergency boration system for anticipated transients without trip faults, Emergency procedure planning to mitigate event progression

  14. 42 CFR 21.47 - Examination; anticipation of meeting qualifications.

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Examination; anticipation of meeting qualifications. 21.47 Section 21.47 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL COMMISSIONED OFFICERS Appointment § 21.47 Examination; anticipation of meeting qualifications. A...

  15. Reward Circuitry Function in Autism during Face Anticipation and Outcomes

    Dichter, Gabriel S.; Richey, J. Anthony; Rittenberg, Alison M.; Sabatino, Antoinette; Bodfish, James W.

    2012-01-01

    The aim of this study was to investigate reward circuitry responses in autism during reward anticipation and outcomes for monetary and social rewards. During monetary anticipation, participants with autism spectrum disorders (ASDs) showed hypoactivation in right nucleus accumbens and hyperactivation in right hippocampus, whereas during monetary…

  16. Age Differences in Risky Decisions: The Role of Anticipated Emotions

    Chen, Yiwei; Ma, Xiaodong

    2009-01-01

    The present study investigated the role of anticipated emotions in risky decisions of young and older adults. Young and older adults were asked to make a choice between an alternative that may have either a very positive or a very negative consequence and an alternative that was relatively safe. Meanwhile, they rated their anticipated emotions if…

  17. Anticipated Guilt for not Helping and Anticipated Warm Glow for Helping are Differently Impacted by Personal Responsibility to Help

    Arvid Erlandsson

    2016-09-01

    Full Text Available One important motivation for people behaving prosocially is that they want to avoid negative and obtain positive emotions. In the prosocial behavior literature however, the motivations to avoid negative emotions (e.g. guilt and to approach positive emotions (e.g. warm glow are rarely separated, and sometimes even aggregated into a single mood-management construct. The aim of this study was to investigate whether anticipated guilt if not helping and anticipated warm glow if helping are influenced similarly or differently when varying situational factors related to personal responsibility to help. Helping scenarios were created and pilot tests established that each helping scenario could be formulated both in a high-responsibility version and in a low-responsibility version. In Study 1 participants read high-responsibility and low-responsibility helping scenarios, and rated either their anticipated guilt if not helping or their anticipated warm glow if helping (i.e. separate evaluation. Study 2 was similar but here participants rated both their anticipated guilt if not helping and their anticipated warm glow if helping (i.e. joint evaluation. Anticipated guilt was clearly higher in the high-responsibility versions, but anticipated warm glow was unaffected (in Studies 1a and 1b, or even higher in the low-responsibility versions (Study 2. In Studies 3 (where anticipated guilt and warm glow were evaluated separately and 4 (where they were evaluated jointly, personal responsibility to help was manipulated within-subjects. Anticipated guilt was again constantly higher in the high-responsibility versions but for many types of responsibility-manipulations, anticipated warm glow was higher in the low-responsibility versions. The results suggest that we anticipate guilt if not fulfilling our responsibility but that we anticipate warm glow primarily when doing over and beyond our responsibility. We argue that future studies investigating motivations for

  18. Anticipated Regret and Omission Bias in HPV Vaccination Decisions

    Jensen, Niels Holm

    2017-01-01

    This study investigated effects of anticipated regret on parents’ HPV vaccination intentions and effects of omission bias on HPV vaccination intentions and vaccine uptake. An online survey was completed by 851 parents of adolescent girls in Denmark, a country where HPV vaccine safety is currently...... heavily debated. Multivariate regression analyses revealed anticipated inaction regret as a significant positive predictor of vaccination intentions, and, anticipated action regret as a significant negative predictor of vaccination intentions. Multivariate analyses also revealed omission bias...... in a hypothetical vaccination vignette as a significant negative predictor of HPV vaccination intention as well as vaccine uptake. Finally, the study tested effects of anticipated regret and omission bias on evaluations of two extisting Danish pro-vaccine campaign videos. Here, the result revealed anticipated...

  19. A new car-following model considering velocity anticipation

    Jun-Fang, Tian; Bin, Jia; Xin-Gang, Li; Zi-You, Gao

    2010-01-01

    The full velocity difference model proposed by Jiang et al. [2001 Phys. Rev. E 64 017101] has been improved by introducing velocity anticipation. Velocity anticipation means the follower estimates the future velocity of the leader. The stability condition of the new model is obtained by using the linear stability theory. Theoretical results show that the stability region increases when we increase the anticipation time interval. The mKdV equation is derived to describe the kink–antikink soliton wave and obtain the coexisting stability line. The delay time of car motion and kinematic wave speed at jam density are obtained in this model. Numerical simulations exhibit that when we increase the anticipation time interval enough, the new model could avoid accidents under urgent braking cases. Also, the traffic jam could be suppressed by considering the anticipation velocity. All results demonstrate that this model is an improvement on the full velocity difference model. (general)

  20. A Review of Hazard Anticipation Training Programs for Young Drivers.

    McDonald, Catherine C; Goodwin, Arthur H; Pradhan, Anuj K; Romoser, Matthew R E; Williams, Allan F

    2015-07-01

    Poor hazard anticipation skills are a risk factor associated with high motor vehicle crash rates of young drivers. A number of programs have been developed to improve these skills. The purpose of this review was to assess the empirical literature on hazard anticipation training for young drivers. Studies were included if they (1) included an assessment of hazard anticipation training outcomes; (2) were published between January 1, 1980 and December 31, 2013 in an English language peer-reviewed journal or conference proceeding; and (3) included at least one group that uniquely comprised a cohort of participants aged anticipation outcomes but none investigated crash effects. Although there is promise in existing programs, future research should include long-term follow-up, evaluate crash outcomes, and assess the optimal timing of hazard anticipation training taking into account the age and experience level of young drivers. Copyright © 2015 Society for Adolescent Health and Medicine. All rights reserved.

  1. Young people's anticipation regarding education and job

    Juul, Tilde Mette; Lundby, Astrid Arbjerg

    ’ decision making competences, but also to an guide the students towards certain educations that is seen to fit the society’s future need for work force, especially vocational education and science education. Despite these initiatives increasing number of students choose to go to gymnasium – and less......In Denmark there is significant political attention towards leading young people faster through the education system. Through new policies and benefit structures the government aims to reduce the number of gap years in the transition between general upper secondary education (‘gymnasium......’) and higher education. At the same time a political reform has made it more difficult to take on leave, switch education and do work experience during the studies. Simultaneously there is increasing attention on student guidance on all educational levels. The aim is on one hand to improve the students...

  2. Dimensions of Anticipated Reaction in Information Management: Anticipating Responses and Outcomes.

    Magsamen-Conrad, Kate

    Many models, theories, and frameworks of information management (e.g., privacy, disclosure, secrets) incorporate the concept of receiver response, both anticipated and actual. Although most if not all information management literature highlights the importance of the response variable, each perspective conceptualizes and/or operationalizes response differently. The lack of consistency across perspectives limits research design, theory testing, and scholars' ability to make comparisons among and across theoretical frameworks, as well as their ability to evaluate research findings within the broader context of information management theory. This project presents a review and synthesis of receiver response within the context of information sharing and decision making, including both immediate responses and longer-term outcomes of sharing the information.

  3. Anticipation from sensation: using anticipating synchronization to stabilize a system with inherent sensory delay.

    Eberle, Henry; Nasuto, Slawomir J; Hayashi, Yoshikatsu

    2018-03-01

    We present a novel way of using a dynamical model for predictive tracking control that can adapt to a wide range of delays without parameter update. This is achieved by incorporating the paradigm of anticipating synchronization (AS), where a 'slave' system predicts a 'master' via delayed self-feedback. By treating the delayed output of the plant as one half of a 'sensory' AS coupling, the plant and an internal dynamical model can be synchronized such that the plant consistently leads the target's motion. We use two simulated robotic systems with differing arrangements of the plant and internal model ('parallel' and 'serial') to demonstrate that this form of control adapts to a wide range of delays without requiring the parameters of the controller to be changed.

  4. A magnetoencephalography study of visual processing of pain anticipation.

    Machado, Andre G; Gopalakrishnan, Raghavan; Plow, Ela B; Burgess, Richard C; Mosher, John C

    2014-07-15

    Anticipating pain is important for avoiding injury; however, in chronic pain patients, anticipatory behavior can become maladaptive, leading to sensitization and limiting function. Knowledge of networks involved in pain anticipation and conditioning over time could help devise novel, better-targeted therapies. With the use of magnetoencephalography, we evaluated in 10 healthy subjects the neural processing of pain anticipation. Anticipatory cortical activity elicited by consecutive visual cues that signified imminent painful stimulus was compared with cues signifying nonpainful and no stimulus. We found that the neural processing of visually evoked pain anticipation involves the primary visual cortex along with cingulate and frontal regions. Visual cortex could quickly and independently encode and discriminate between visual cues associated with pain anticipation and no pain during preconscious phases following object presentation. When evaluating the effect of task repetition on participating cortical areas, we found that activity of prefrontal and cingulate regions was mostly prominent early on when subjects were still naive to a cue's contextual meaning. Visual cortical activity was significant throughout later phases. Although visual cortex may precisely and time efficiently decode cues anticipating pain or no pain, prefrontal areas establish the context associated with each cue. These findings have important implications toward processes involved in pain anticipation and maladaptive pain conditioning. Copyright © 2014 the American Physiological Society.

  5. Fertility and apparent genetic anticipation in Lynch syndrome.

    Stupart, Douglas; Win, Aung Ko; Jenkins, Mark; Winship, Ingrid M; Goldberg, Paul; Ramesar, Rajkumar

    2014-09-01

    Genetic anticipation is the phenomenon in which age of onset of an inherited disorder decreases in successive generations. Inconsistent evidence suggests that this occurs in Lynch syndrome. A possible cause for apparent anticipation is fecundity bias, which occurs if the disease adversely affects fertility. The purpose of this study was to determine the effect of age of diagnosis of colorectal cancer (CRC) on lifetime fertility in Lynch syndrome, and whether this can falsely create the appearance of genetic anticipation. A computer model simulated age of diagnosis of CRC in hypothetical Lynch syndrome carriers and their offspring. The model assumed similar age distribution of CRC across generations (i.e. that there was no true anticipation). Age distribution of CRC diagnosis, and lifetime fertility rates (grouped by age of diagnosis of CRC) were determined from the Australasian Colorectal Cancer Family Registry (ACCFR). Apparent anticipation was calculated by comparing ages of diagnosis of CRC in affected parent-child pairs. A total of 1,088 patients with CRC were identified from the ACCFR. Total lifetime (cohort) fertility was related to age of diagnosis of CRC (correlation coefficient 0.13, P = 0.0001). In the simulation, apparent anticipation was 1.8 ± 0.54 years (P = 0.0044). Observed apparent anticipation in the ACCFR cohort was 4.8 ± 1.73 years (P = 0.0064). There was no difference in apparent anticipation between the simulate d and observed parent-child pairs (P = 0.89). The appearance of genetic anticipation in Lynch syndrome can be falsely created due to changes in fertility.

  6. SAP Nuclear Competence Centre

    Andrlova, Z.

    2009-01-01

    In this issue we continue and introduce the SAP Nuclear Competence Centre and its head Mr. Igor Dzama. SAP Nuclear Competence Centrum is one of the fi rst competence centres outside ENEL headquarters. It should operate in Slovakia and should have competencies within the whole Enel group. We are currently dealing with the issues of organisation and funding. We are trying to balance the accountability to the NPP directors and to the management of the competence centres at Enel headquarters; we are looking at the relations between the competence centres within the group and defining the services that we will provide for the NPPs. author)

  7. Canadian Irradiation Centre

    1987-05-01

    The Canadian Irradiation Centre is a non-profit cooperative project between Atomic Energy of Canada Limited, Radiochemical Company and Universite du Quebec, Institut Armand-Frappier, Centre for Applied Research in Food Science. The Centre's objectives are to develop, demonstrate and promote Canada's radiation processing technology and its applications by conducting applied research; training technical, professional and scientific personnel; educating industry and government; demonstrating operational and scientific procedures; developing processing procedures and standards, and performing product and market acceptance trials. This pamphlet outlines the history of radoation technology and the services offered by the Canadian Irradiation Centre

  8. Plant Betterment as Anticipated Measure For Plant Life Management

    Louvat, J. P.

    1991-01-01

    A lot of modifications have been made since critically on each of the 28 standardized 900 MW class PWR units in France. Most of this technical upgrading was accomplished to facilitate operation, improve availability, or bring the unit design in line with evolving regulatory requirements, but a substantial part of the modifications was dedicated to Plant Life Management. As part of the program launched by EDF for plant life management, this paper introduces the Frustum's contribution for plant betterment and enhancement of reactor operation concurrently to ensure or extend plant service life. The solutions contemplated in this field are provided to reduce the frequency of unexpected reactor trip occurrences, to mitigate their negative effects or to smooth off the reactor operation and thus the magnitude of associated transients. The lifetime evaluation of NPP is basically an economical exercise, which tries to determine how long the operation of the plant will remain competitive, taking into account the long term perspective maintenance costs. There cannot be any conflict between lifetime and safety considerations, based upon the pituitary requisite that the safety requirement must be met at any time of the operation. Plant life management needs a consistent approach that can not be improvised on a case by case basis. Instead, it must be kept in mind from the very beginning of unit operation. This is the sense of the backfitting and technical upgrading carried out in France for the PWRs of the 900 MW class. It is thanks to this necessary anticipation that plant life will be actually managed, giving benefit both from the standpoint of availability and from that of the service lives of sensitive components. Substantial savings will thus be obtained

  9. Collective motion with anticipation: flocking, spinning, and swarming.

    Morin, Alexandre; Caussin, Jean-Baptiste; Eloy, Christophe; Bartolo, Denis

    2015-01-01

    We investigate the collective dynamics of self-propelled particles able to probe and anticipate the orientation of their neighbors. We show that a simple anticipation strategy hinders the emergence of homogeneous flocking patterns. Yet anticipation promotes two other forms of self-organization: collective spinning and swarming. In the spinning phase, all particles follow synchronous circular orbits, while in the swarming phase, the population condensates into a single compact swarm that cruises coherently without requiring any cohesive interactions. We quantitatively characterize and rationalize these phases of polar active matter and discuss potential applications to the design of swarming robots.

  10. U.S. Dental Specialty Residents' Expectations and Anticipated Benefits of Academic Employment.

    Nazarova, Elena; Martin-Peele, Melanie; Fifield, Judith

    2016-10-01

    The aims of this study were to assess features of an academic career that dental specialty residents, as a group and by gender, find most attractive and to identify what determines their expectations for responsibilities and professional growth in academic employment. In November 2013, an invitation to participate in the study along with a link to an online survey was sent to the 407 U.S. program directors of six of the dental specialties (endodontics, oral and maxillofacial surgery, pediatric dentistry, periodontics, prosthodontics, and orthodontics), asking them to forward the survey to their residents. A total of 287 residents responded (112 [41.3%] female and 159 [58.7%] male) out of 4,400 enrolled in these specialty training programs (6.5% response rate). The female respondents were significantly more interested in joining academia than were the male respondents (female 48%; male 31.5%; pgenders were attracted to academic dentistry by opportunities for intellectual and professional stimulation, but the lifestyle of academicians was significantly more important for the female respondents. The most important feature of a successful academic career for the female respondents was the ability to have a good balance between career and personal life. While opportunity to conduct research was a positive feature for all residents interested in academia and both male and female respondents agreed strongly on the need for collaboration between faculty members for productive research, male respondents agreed significantly more than female respondents that faculty members should conduct independent research. Faculty members' feedback about academic employment were a significantly positive influence on those planning an academic career compared to those planning to enter private practice. This study found that the female and male residents differed in their expectations of responsibilities and professional growth in academic employment. These results may be useful for academic dental institutions and organizations when developing faculty recruitment and retention programs.

  11. Visual Benefits in Apparent Motion Displays: Automatically Driven Spatial and Temporal Anticipation Are Partially Dissociated.

    Merle-Marie Ahrens

    Full Text Available Many behaviourally relevant sensory events such as motion stimuli and speech have an intrinsic spatio-temporal structure. This will engage intentional and most likely unintentional (automatic prediction mechanisms enhancing the perception of upcoming stimuli in the event stream. Here we sought to probe the anticipatory processes that are automatically driven by rhythmic input streams in terms of their spatial and temporal components. To this end, we employed an apparent visual motion paradigm testing the effects of pre-target motion on lateralized visual target discrimination. The motion stimuli either moved towards or away from peripheral target positions (valid vs. invalid spatial motion cueing at a rhythmic or arrhythmic pace (valid vs. invalid temporal motion cueing. Crucially, we emphasized automatic motion-induced anticipatory processes by rendering the motion stimuli non-predictive of upcoming target position (by design and task-irrelevant (by instruction, and by creating instead endogenous (orthogonal expectations using symbolic cueing. Our data revealed that the apparent motion cues automatically engaged both spatial and temporal anticipatory processes, but that these processes were dissociated. We further found evidence for lateralisation of anticipatory temporal but not spatial processes. This indicates that distinct mechanisms may drive automatic spatial and temporal extrapolation of upcoming events from rhythmic event streams. This contrasts with previous findings that instead suggest an interaction between spatial and temporal attention processes when endogenously driven. Our results further highlight the need for isolating intentional from unintentional processes for better understanding the various anticipatory mechanisms engaged in processing behaviourally relevant stimuli with predictable spatio-temporal structure such as motion and speech.

  12. Anticipating the Environmental Impacts and Behavioral Drivers of Deep Decarbonization

    EPA is seeking regular and early career applications proposing research that will contribute to an improved ability to understand and anticipate the public health and environmental impacts and behavioral drivers of significant changes in energy consumption

  13. Fear appeals in HIV prevention: the role of anticipated regret.

    Smerecnik, Chris M R; Ruiter, Robert A C

    2010-10-01

    The present study examined the role of a number of cognitive beliefs (i.e. attitude, subjective norm, anticipated regret, and self-efficacy) in explaining the effects of fear appeal information on behavioral motivation. A randomized experiment with a 2 (threat: low versus high) × 2 (coping: low versus high) between-subjects design was used in the study. Undergraduates were exposed to one of four scenario messages that presented high or low threat information about HIV/AIDS combined with high or low coping information with regard to condom use in HIV prevention. Explorative analyses revealed that only anticipated regret qualified as a mediator of the effect of the fear appeal message on intention. High coping information was observed to increase anticipated regret, which increased the intention to use condoms. Anticipated regret mediated the coping-intention relationship. This finding furthers our understanding of the working mechanisms of fear appeals in HIV prevention.

  14. Defender's Edge: Utilizing Intelligent Agent Technology to Anticipate Terrorist Acts

    Scheiber, Lane

    2003-01-01

    ...), to the problem of anticipating terrorist acts. Two areas in which IAs could play a significant role are in the development and maintenance of a real-time picture of terrorist activity, and in predicting potential occurrences of terrorist acts...

  15. Experienced and anticipated discrimination against people with schizophrenia

    Milačić-Vidojević Ivona

    2011-01-01

    Full Text Available Aim of this research was to describe the nature, direction and severity of anticipated and experienced discrimination reported by people with schizophrenia. We applied interview to 50 patients with diagnosis of schizophrenia in two psychiatric hospitals in Belgrade. Discrimination was measured with discrimination and stigma scale (DISC which produce 3 subscores, positive experienced discrimination, negative experienced discrimination and anticipated discrimination. The same scale was used in cross-cultural research in 27 european countries. Results have shown that participants from Serbia do not recognize discrimination in all areas of life equally. The discrimination recognized is more frequentlly negative then positive and is associated with existentially important realms of life. Due to anticipated discrimination participants in our study prevent themselves from looking for a close relationship. Anticipated discrimination could not be predicted on the grounds of experienced, positive or negative discrimination.

  16. Research Informed Science Enrichment Programs at the Gravity Discovery Centre

    Venville, Grady; Blair, David; Coward, David; Deshon, Fred; Gargano, Mark; Gondwe, Mzamose; Heary, Auriol; Longnecker, Nancy; Pitts, Marina; Zadnik, Marjan

    2012-01-01

    Excursions to museums and science centres generally are great fun for students and teachers. The potential educational benefits beyond enjoyment, however, are rarely realised or analysed for their efficacy. The purpose of this paper is to describe four educational enrichment programs delivered at the Gravity Discovery Centre (GDC), near Gingin,…

  17. Client Centred Desing

    Ørngreen, Rikke; Nielsen, Janni; Levinsen, Karin

    2008-01-01

    In this paper we argue for the use of Client Centred preparation phases when designing complex systems. Through Client Centred Design human computer interaction can extend the focus on end-users to alse encompass the client's needs, context and resources....

  18. Experimental evidence of enhancement in the anticipation time by cascading

    Baraik, Abhijit; Singh, Harpartap; Parmananda, P.

    2014-01-01

    We have studied and verified experimentally the enhancement in the anticipation time by cascading Chua's circuits. The experiments have been carried out in a one dimensional array of Chua's circuits (2 to 8) coupled unidirectionally, such that each one acts as a master for the next one. By doing so, it has been observed that the anticipation time increases with an increase in the array size. Moreover, the numerical simulations of an array of eighty Chua's circuits verify the experimental observations.

  19. The anticipatory profile. An attempt to describe anticipation as process

    Nadin, Mihai

    2012-01-01

    Inductive class representation and the more comprehensive evolving transformation system (ETS) are congenial to the subject matter of anticipation. In substantiating this assertion, we examine the epistemological premises of a new form of representation, of interest to pattern recognition and Artificial Intelligence (AI), but even more to the study of living systems. Some concepts, such as classes, time and time scale, and generative processes are examined in detail with respect to their pertinence to anticipation. Finally, pattern generation and ETS programming are suggested.

  20. The reaction of stock market returns to anticipated unemployment

    Taamouti, Abderrahim; Gonzalo Muñoz, Jesús

    2012-01-01

    We empirically investigate the short-run impact of anticipated and unanticipated unemployment rates on stock prices. We particularly examine the nonlinearity in stock market's reaction to unemployment rate and study the effect at each individual point (quantile) of stock return distribution. Using nonparametric Granger causality and quantile regression based tests, we find that, contrary to the general findings in the literature, only anticipated unemployment rate has a strong impact on stock...

  1. Neurophysiology of action anticipation in athletes: A systematic review.

    Smith, Daniel M

    2016-01-01

    The purpose of this study was to provide a systematic review of action anticipation studies using functional neuroimaging or brain stimulation during a sport-specific anticipation task. A total of 15 studies from 2008 to 2014 were evaluated and are reported in four sections: expert-novice samples, action anticipation tasks, neuroimaging and stimulation techniques, and key findings. Investigators examined a wide range of action anticipation scenarios specific to eight different sports and utilized functional magnetic resonance imaging (fMRI), electroencephalogram (EEG), and transcranial magnetic stimulation (TMS). Expert-novice comparisons were commonly used to investigate differences in action anticipation performance and neurophysiology. Experts tended to outperform novices, and an extensive array of brain structures were reported to be involved differently for experts and novices during action anticipation. However, these neurophysiological findings were generally inconsistent across the studies reviewed. The discussion focuses on strengths and four key limitations. The conclusion posits remaining questions and recommendations for future research. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Disentangling reward anticipation with simultaneous pupillometry / fMRI.

    Schneider, Max; Leuchs, Laura; Czisch, Michael; Sämann, Philipp G; Spoormaker, Victor I

    2018-05-05

    The reward system may provide an interesting intermediate phenotype for anhedonia in affective disorders. Reward anticipation is characterized by an increase in arousal, and previous studies have linked the anterior cingulate cortex (ACC) to arousal responses such as dilation of the pupil. Here, we examined pupil dynamics during a reward anticipation task in forty-six healthy human subjects and evaluated its neural correlates using functional magnetic resonance imaging (fMRI). Pupil size showed a strong increase during monetary reward anticipation, a moderate increase during verbal reward anticipation and a decrease during control trials. For fMRI analyses, average pupil size and pupil change were computed in 1-s time bins during the anticipation phase. Activity in the ventral striatum was inversely related to the pupil size time course, indicating an early onset of activation and a role in reward prediction processing. Pupil dilations were linked to increased activity in the salience network (dorsal ACC and bilateral insula), which likely triggers an increase in arousal to enhance task performance. Finally, increased pupil size preceding the required motor response was associated with activity in the ventral attention network. In sum, pupillometry provides an effective tool for disentangling different phases of reward anticipation, with relevance for affective symptomatology. Copyright © 2018 Elsevier Inc. All rights reserved.

  3. Temporal dynamics of reward anticipation in the human brain.

    Zhang, Yuanyuan; Li, Qi; Wang, Zhao; Liu, Xun; Zheng, Ya

    2017-09-01

    Reward anticipation is a complex process including cue evaluation, motor preparation, and feedback anticipation. The present study investigated whether these psychological processes were dissociable on neural dynamics in terms of incentive valence and approach motivation. We recorded EEG when participants were performing a monetary incentive delay task, and found a cue-P3 during the cue-evaluation stage, a contingent negative variation (CNV) during the motor-preparation stage, and a stimulus-preceding negativity (SPN) during the feedback-anticipation stage. Critically, both the cue-P3 and SPN exhibited an enhanced sensitivity to gain versus loss anticipation, which was not observed for the CNV. Moreover, both the cue-P3 and SPN, instead of the CNV, for gain anticipation selectively predicted the participants' approach motivation as measured in a following effort expenditure for rewards task, particularly when reward uncertainty was maximal. Together, these results indicate that reward anticipation consists of several sub-stages, each with distinct functional significance, thus providing implications for neuropsychiatric diseases characterized by dysfunction in anticipatory reward processing. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Does expert perceptual anticipation transfer to a dissimilar domain?

    Müller, Sean; McLaren, Michelle; Appleby, Brendyn; Rosalie, Simon M

    2015-06-01

    The purpose of this experiment was to extend theoretical understanding of transfer of learning by investigating whether expert perceptual anticipation skill transfers to a dissimilar domain. The capability of expert and near-expert rugby players as well as novices to anticipate skill type within rugby (learning sport) was first examined using a temporal occlusion paradigm. Participants watched video footage of an opponent performing rugby skill types that were temporally occluded at different points in the opponent's action and then made a written prediction. Thereafter, the capability of participants to transfer their anticipation skill to predict pitch type in baseball (transfer sport) was examined. Participants watched video footage of a pitcher throwing different pitch types that were temporally occluded and made a written prediction. Results indicated that expert and near-expert rugby players anticipated significantly better than novices across all occlusion conditions. However, none of the skill groups were able to transfer anticipation skill to predict pitch type in baseball. The findings of this paper, along with existing literature, support the theoretical prediction that transfer of perceptual anticipation is expertise dependent and restricted to similar domains. (c) 2015 APA, all rights reserved).

  5. Anticipated affective consequences of physical activity adoption and maintenance.

    Dunton, Genevieve Fridlund; Vaughan, Elaine

    2008-11-01

    The expected emotional consequences of future actions are thought to play an important role in health behavior change. This research examined whether anticipated affective consequences of success and failure vary across stages of physical activity change and differentially predict physical activity adoption as compared to maintenance. Using a prospective design over a 3-month period, a community sample of 329 healthy, middle-aged adults were assessed at 2 time points. Anticipated positive and negative emotions, stage of behavior change (precontemplation [PC], contemplation [C], preparation [P], action [A], maintenance [M]), and level of physical activity. At baseline, anticipated positive emotions were greater in C versus PC, whereas anticipated negative emotions were greater in M versus A and in M versus P. Higher anticipated positive but not negative emotions predicted physical activity adoption and maintenance after 3 months. Although the expected affective consequences of future success and failure differentiated among individuals in the early and later stages of physical activity change, respectively; only the anticipated affective consequences of success predicted future behavior.

  6. The Frequencies of Different Inborn Errors of Metabolism in Adult Metabolic Centres: Report from the SSIEM Adult Metabolic Physicians Group

    Sirrs, S.; Hollak, C.; Merkel, M.; Sechi, A.; Glamuzina, E.; Janssen, M.C.H.; Lachmann, R.; Langendonk, J.; Scarpelli, M.; Omran, T. Ben; Mochel, F.; Tchan, M.C.

    2016-01-01

    BACKGROUND: There are few centres which specialise in the care of adults with inborn errors of metabolism (IEM). To anticipate facilities and staffing needed at these centres, it is of interest to know the distribution of the different disorders. METHODS: A survey was distributed through the

  7. Research on public logistics centre as tool for cooperation

    A. Jaržemskis

    2007-03-01

    Full Text Available This paper focuses on logistics centre concept and benefits for users. Intermodal benefit, forwarders impact, IT solutions, new transport flows due to synergy, better supply chain management, additional services, cost sharing, economies of scale, quality of the services, know-how, joint marketing impact, and benefit for growth of third-party logistics services are presented. The main bottlenecks such as duration of planning logistics centres process, pressure to land use for other purposes and problems caused by legislation are described. Results of pilot study of benefits from business cooperation are presented and concluded as well.

  8. Anticipation in turn-taking: mechanisms and information sources.

    Riest, Carina; Jorschick, Annett B; de Ruiter, Jan P

    2015-01-01

    During conversations participants alternate smoothly between speaker and hearer roles with only brief pauses and overlaps. There are two competing types of accounts about how conversationalists accomplish this: (a) the signaling approach and (b) the anticipatory ('projection') approach. We wanted to investigate, first, the relative merits of these two accounts, and second, the relative contribution of semantic and syntactic information to the timing of next turn initiation. We performed three button-press experiments using turn fragments taken from natural conversations to address the following questions: (a) Is turn-taking predominantly based on anticipation or on reaction, and (b) what is the relative contribution of semantic and syntactic information to accurate turn-taking. In our first experiment we gradually manipulated the information available for anticipation of the turn end (providing information about the turn end in advance to completely removing linguistic information). The results of our first experiment show that the distribution of the participants' estimation of turn-endings for natural turns is very similar to the distribution for pure anticipation. We conclude that listeners are indeed able to anticipate a turn-end and that this strategy is predominantly used in turn-taking. In Experiment 2 we collected purely reacted responses. We used the distributions from Experiments 1 and 2 together to estimate a new dependent variable called Reaction Anticipation Proportion. We used this variable in our third experiment where we manipulated the presence vs. absence of semantic and syntactic information by low-pass filtering open-class and closed class words in the turn. The results suggest that for turn-end anticipation, both semantic and syntactic information are needed, but that the semantic information is a more important anticipation cue than syntactic information.

  9. Anticipated debt and financial stress in medical students.

    Morra, Dante J; Regehr, Glenn; Ginsburg, Shiphra

    2008-01-01

    While medical student debt is increasing, the effect of debt on student well-being and performance remains unclear. As a part of a larger study examining medical student views of their future profession, data were collected to examine the role that current and anticipated debt has in predicting stress among medical students. A survey was administered to medical students in all four years at the University of Toronto. Of the 804 potential respondents across the four years of training, 549 surveys had sufficient data for inclusion in this analysis, for a response rate of 68%. Through multiple regression analysis, we evaluated the correlation between current and anticipated debt and financial stress. Although perceived financial stress correlates with both current and anticipated debt levels, anticipated debt was able to account for an additional 11.5% of variance in reported stress when compared to current debt levels alone. This study demonstrates a relationship between perceived financial stress and debt levels, and suggests that anticipated debt levels might be a more robust metric to capture financial burden, as it standardizes for year of training and captures future financial liabilities (future tuition and other future expenses).

  10. Utilization of cues in action anticipation in table tennis players.

    Zhao, Qi; Lu, Yingzhi; Jaquess, Kyle J; Zhou, Chenglin

    2018-04-11

    By manipulating the congruency between body kinematics and subsequent ball trajectory, this study investigated the anticipation capabilities of regional-level, college-level, and novice table tennis players using a full video simulation occluder paradigm. Participants watched footage containing congruent, incongruent, or no ball trajectory information, to predict the landing point of the ball. They were required to choose between two potential locations to make their prediction. Percent accuracy and relevant indexes (d-prime, criterion, effect size) were calculated for each condition. Results indicated that experienced table tennis players (both regional and college players) were superior to novices in the ability to anticipate ball trajectory using kinematic information, but no difference was found between regional-level and college-level players. The findings of this study further demonstrate the superior anticipation ability of experienced table tennis players. Furthermore, the present result suggests that there may be a certain "baseline" level of motor experience in racquet sports for effective action anticipation, while the addition of further motor experience does not appear to assist direction anticipation.

  11. Affective traits link to reliable neural markers of incentive anticipation.

    Wu, Charlene C; Samanez-Larkin, Gregory R; Katovich, Kiefer; Knutson, Brian

    2014-01-01

    While theorists have speculated that different affective traits are linked to reliable brain activity during anticipation of gains and losses, few have directly tested this prediction. We examined these associations in a community sample of healthy human adults (n=52) as they played a Monetary Incentive Delay task while undergoing functional magnetic resonance imaging (FMRI). Factor analysis of personality measures revealed that subjects independently varied in trait Positive Arousal and trait Negative Arousal. In a subsample (n=14) retested over 2.5years later, left nucleus accumbens (NAcc) activity during anticipation of large gains (+$5.00) and right anterior insula activity during anticipation of large losses (-$5.00) showed significant test-retest reliability (intraclass correlations>0.50, p'santicipation of large gains, while trait Negative Arousal correlated with individual differences in right anterior insula activity during anticipation of large losses. Associations of affective traits with neural activity were not attributable to the influence of other potential confounds (including sex, age, wealth, and motion). Together, these results demonstrate selective links between distinct affective traits and reliably-elicited activity in neural circuits associated with anticipation of gain versus loss. The findings thus reveal neural markers for affective dimensions of healthy personality, and potentially for related psychiatric symptoms. © 2013. Published by Elsevier Inc. All rights reserved.

  12. Differences in gaze anticipation for locomotion with and without vision

    Authié, Colas N.; Hilt, Pauline M.; N'Guyen, Steve; Berthoz, Alain; Bennequin, Daniel

    2015-01-01

    Previous experimental studies have shown a spontaneous anticipation of locomotor trajectory by the head and gaze direction during human locomotion. This anticipatory behavior could serve several functions: an optimal selection of visual information, for instance through landmarks and optic flow, as well as trajectory planning and motor control. This would imply that anticipation remains in darkness but with different characteristics. We asked 10 participants to walk along two predefined complex trajectories (limaçon and figure eight) without any cue on the trajectory to follow. Two visual conditions were used: (i) in light and (ii) in complete darkness with eyes open. The whole body kinematics were recorded by motion capture, along with the participant's right eye movements. We showed that in darkness and in light, horizontal gaze anticipates the orientation of the head which itself anticipates the trajectory direction. However, the horizontal angular anticipation decreases by a half in darkness for both gaze and head. In both visual conditions we observed an eye nystagmus with similar properties (frequency and amplitude). The main difference comes from the fact that in light, there is a shift of the orientations of the eye nystagmus and the head in the direction of the trajectory. These results suggest that a fundamental function of gaze is to represent self motion, stabilize the perception of space during locomotion, and to simulate the future trajectory, regardless of the vision condition. PMID:26106313

  13. The Bruce Energy Centre

    Jones, R.I.

    1982-06-01

    The Bruce Energy Centre Development Corporation is a joint venture of the Ontario Energy Corporation and 6 private companies formed to market surplus steam from the Bruce Nuclear Power Development. The corporation will also sell or lease land near Bruce NPD. The Bruce Energy Centre has an energy output of 900 BTU per day per dollar invested. Potential customers include greenhouse operators, aquaculturalists, food and beverage manufacturers, and traditional manufacturers

  14. The Aube centre

    1996-07-01

    This educational booklet is devoted to a general presentation of the Aube radioactive wastes storage centre. After a short presentation of the Andra, the French national agency for the management of radioactive wastes, it gives some general information about radioactive wastes (origin, classification), containers (quality assurance and different types), wastes transportation (planning, safety), and about the Aube centre itself: description, treatment and conditioning of drums (compacting and injection), storage facilities, geological situation of the site, and environmental controls. (J.S.)

  15. CENTRE FOR GEOMETRICAL METROLOGY

    De Chiffre, Leonardo

    The objective of this Annual Report is to give a general introduction to CGM as well as to give an account of the tasks carried out using the facilities of CGM's Instrument Centre during 1998 and 1999.......The objective of this Annual Report is to give a general introduction to CGM as well as to give an account of the tasks carried out using the facilities of CGM's Instrument Centre during 1998 and 1999....

  16. Potential of satellite-derived ecosystem functional attributes to anticipate species range shifts

    Alcaraz-Segura, Domingo; Lomba, Angela; Sousa-Silva, Rita; Nieto-Lugilde, Diego; Alves, Paulo; Georges, Damien; Vicente, Joana R.; Honrado, João P.

    2017-05-01

    In a world facing rapid environmental changes, anticipating their impacts on biodiversity is of utmost relevance. Remotely-sensed Ecosystem Functional Attributes (EFAs) are promising predictors for Species Distribution Models (SDMs) by offering an early and integrative response of vegetation performance to environmental drivers. Species of high conservation concern would benefit the most from a better ability to anticipate changes in habitat suitability. Here we illustrate how yearly projections from SDMs based on EFAs could reveal short-term changes in potential habitat suitability, anticipating mid-term shifts predicted by climate-change-scenario models. We fitted two sets of SDMs for 41 plant species of conservation concern in the Iberian Peninsula: one calibrated with climate variables for baseline conditions and projected under two climate-change-scenarios (future conditions); and the other calibrated with EFAs for 2001 and projected annually from 2001 to 2013. Range shifts predicted by climate-based models for future conditions were compared to the 2001-2013 trends from EFAs-based models. Projections of EFAs-based models estimated changes (mostly contractions) in habitat suitability that anticipated, for the majority (up to 64%) of species, the mid-term shifts projected by traditional climate-change-scenario forecasting, and showed greater agreement with the business-as-usual scenario than with the sustainable-development one. This study shows how satellite-derived EFAs can be used as meaningful essential biodiversity variables in SDMs to provide early-warnings of range shifts and predictions of short-term fluctuations in suitable conditions for multiple species.

  17. Anticipated Changes in Conducting Scientific Data-Analysis Research in the Big-Data Era

    Kuo, Kwo-Sen; Seablom, Michael; Clune, Thomas; Ramachandran, Rahul

    2014-05-01

    A Big-Data environment is one that is capable of orchestrating quick-turnaround analyses involving large volumes of data for numerous simultaneous users. Based on our experiences with a prototype Big-Data analysis environment, we anticipate some important changes in research behaviors and processes while conducting scientific data-analysis research in the near future as such Big-Data environments become the mainstream. The first anticipated change will be the reduced effort and difficulty in most parts of the data management process. A Big-Data analysis environment is likely to house most of the data required for a particular research discipline along with appropriate analysis capabilities. This will reduce the need for researchers to download local copies of data. In turn, this also reduces the need for compute and storage procurement by individual researchers or groups, as well as associated maintenance and management afterwards. It is almost certain that Big-Data environments will require a different "programming language" to fully exploit the latent potential. In addition, the process of extending the environment to provide new analysis capabilities will likely be more involved than, say, compiling a piece of new or revised code. We thus anticipate that researchers will require support from dedicated organizations associated with the environment that are composed of professional software engineers and data scientists. A major benefit will likely be that such extensions are of higher-quality and broader applicability than ad hoc changes by physical scientists. Another anticipated significant change is improved collaboration among the researchers using the same environment. Since the environment is homogeneous within itself, many barriers to collaboration are minimized or eliminated. For example, data and analysis algorithms can be seamlessly shared, reused and re-purposed. In conclusion, we will be able to achieve a new level of scientific productivity in the

  18. Anticipated Changes in Conducting Scientific Data-Analysis Research in the Big-Data Era

    Kuo, Kwo-Sen; Seablom, Michael; Clune, Thomas; Ramachandran, Rahul

    2014-01-01

    A Big-Data environment is one that is capable of orchestrating quick-turnaround analyses involving large volumes of data for numerous simultaneous users. Based on our experiences with a prototype Big-Data analysis environment, we anticipate some important changes in research behaviors and processes while conducting scientific data-analysis research in the near future as such Big-Data environments become the mainstream. The first anticipated change will be the reduced effort and difficulty in most parts of the data management process. A Big-Data analysis environment is likely to house most of the data required for a particular research discipline along with appropriate analysis capabilities. This will reduce the need for researchers to download local copies of data. In turn, this also reduces the need for compute and storage procurement by individual researchers or groups, as well as associated maintenance and management afterwards. It is almost certain that Big-Data environments will require a different "programming language" to fully exploit the latent potential. In addition, the process of extending the environment to provide new analysis capabilities will likely be more involved than, say, compiling a piece of new or revised code.We thus anticipate that researchers will require support from dedicated organizations associated with the environment that are composed of professional software engineers and data scientists. A major benefit will likely be that such extensions are of higherquality and broader applicability than ad hoc changes by physical scientists. Another anticipated significant change is improved collaboration among the researchers using the same environment. Since the environment is homogeneous within itself, many barriers to collaboration are minimized or eliminated. For example, data and analysis algorithms can be seamlessly shared, reused and re-purposed. In conclusion, we will be able to achieve a new level of scientific productivity in the Big

  19. Day-Ahead Anticipation of Complex Network Vulnerability

    Stefanov, S. Z.; Wang, Paul P.

    2017-11-01

    In this paper, a day-ahead anticipation of complex network vulnerability for an intentional threat of an attack or a shock is carried out. An ecological observer is introduced for that reason, which is a watch in the intentional multiverse, tiled by cells; dynamics of the intentional threat for a day-ahead is characterized by a space-time cell; spreading of the intentional threat is derived from its energy; duration of the intentional threat is found by the self-assembling of a space-time cell; the lower bound of probability is assessed to anticipate for a day-ahead the intentional threat; it is indicated that this vulnerability anticipation for a day-ahead is right when the intentional threat leads to dimension doubling of the complex network.

  20. Inherent Anticipation in the Pharmaceutical and Biotechnology Industries.

    Goldman, Michael; Evans, Georgia; Zappia, Andrew

    2015-04-15

    Pharmaceutical and biotech research often involves discovering new properties of, or new methods to use, existing compositions. The doctrine of inherent anticipation, however, prevents the issuance and/or validity of a patent for discoveries deemed to have been implicitly disclosed in the prior art. This can be a barrier to patent rights in these technologies. Inherent anticipation therefore creates uncertainty for patent protection in the pharmaceutical and biotech sciences. Despite this uncertainty, Federal Circuit jurisprudence provides guidance on the boundaries of the inherent anticipation doctrine. In view of the case law, certain strategies may be employed to protect inventions that may potentially be viewed as inherent in the prior art. Copyright © 2015 Cold Spring Harbor Laboratory Press; all rights reserved.

  1. Uncertainty during pain anticipation: the adaptive value of preparatory processes.

    Seidel, Eva-Maria; Pfabigan, Daniela M; Hahn, Andreas; Sladky, Ronald; Grahl, Arvina; Paul, Katharina; Kraus, Christoph; Küblböck, Martin; Kranz, Georg S; Hummer, Allan; Lanzenberger, Rupert; Windischberger, Christian; Lamm, Claus

    2015-02-01

    Anticipatory processes prepare the organism for upcoming experiences. The aim of this study was to investigate neural responses related to anticipation and processing of painful stimuli occurring with different levels of uncertainty. Twenty-five participants (13 females) took part in an electroencephalography and functional magnetic resonance imaging (fMRI) experiment at separate times. A visual cue announced the occurrence of an electrical painful or nonpainful stimulus, delivered with certainty or uncertainty (50% chance), at some point during the following 15 s. During the first 2 s of the anticipation phase, a strong effect of uncertainty was reflected in a pronounced frontal stimulus-preceding negativity (SPN) and increased fMRI activation in higher visual processing areas. In the last 2 s before stimulus delivery, we observed stimulus-specific preparatory processes indicated by a centroparietal SPN and posterior insula activation that was most pronounced for the certain pain condition. Uncertain anticipation was associated with attentional control processes. During stimulation, the results revealed that unexpected painful stimuli produced the strongest activation in the affective pain processing network and a more pronounced offset-P2. Our results reflect that during early anticipation uncertainty is strongly associated with affective mechanisms and seems to be a more salient event compared to certain anticipation. During the last 2 s before stimulation, attentional control mechanisms are initiated related to the increased salience of uncertainty. Furthermore, stimulus-specific preparatory mechanisms during certain anticipation also shaped the response to stimulation, underlining the adaptive value of stimulus-targeted preparatory activity which is less likely when facing an uncertain event. © 2014 Wiley Periodicals, Inc.

  2. Adaptive and Rational Anticipations in Risk Management Systems and Economy

    Dubois, Daniel M.; Holmberg, Stig C.

    2010-11-01

    The global financial crisis of year 2009 is explained as a result of uncoordinated risk management decisions in business firms and economic organisations. The underlying reason for this can be found in the current financial system. As the financial market has lost much of its direct coupling to the concrete economy it provides misleading information to economic decision makers at all levels. Hence, the financial system has moved from a state of moderate and slow cyclical fluctuations into a state of fast and chaotic ones. Those misleading decisions can further be described, but not explained, by help of adaptive and rational expectations from macroeconomic theory. In this context, AE, the Adaptive Expectations are related to weak passive Exo-anticipation, and RE, the Rational expectations can be related to a strong, active and design oriented anticipation. The shortcomings of conventional cures, which builds on a reactive paradigm, have already been demonstrated in economic literature and are here further underlined by help of Ashby's "Law of Requisite Variety", Weaver's distinction between systems of "Disorganized Complexity" and those of "Organized Complexity", and Klir's "Reconstructability Analysis". Anticipatory decision-making is hence here proposed as a replacement to current expectation based and passive risk management. An anticipatory model of the business cycle is presented for supporting that proposition. The model, which is an extension of the Kaldor-Kalecki model, includes both retardation and anticipation. While cybernetics with the feedback process in control system deals with an explicit goal or purpose given to a system, the anticipatory system discussed here deals with a behaviour for which the future state of the system is built by the system itself, without explicit goal. A system with weak anticipation is based on a predictive model of the system, while a system with strong anticipation builds its own future by itself. Numerical simulations on

  3. Experimental evidence of enhancement in the anticipation time by cascading

    Baraik, Abhijit; Singh, Harpartap; Parmananda, P.

    2014-04-01

    We have studied and verified experimentally the enhancement in the anticipation time by cascading Chua's circuits. The experiments have been carried out in a one dimensional array of Chua's circuits (2 to 8) coupled unidirectionally, such that each one acts as a master for the next one. By doing so, it has been observed that the anticipation time increases with an increase in the array size. Moreover, the numerical simulations of an array of eighty Chua's circuits verify the experimental observations.

  4. Analyses of anticipated transient without scram events in SMART

    Kim, Hyung Rae; Chun, Ji Han; Kim, Soo Hyoung; Yang, Soo Hyung; Bae, Kyoo Hwan

    2012-01-01

    SMART is a small integral reactor, which was developed at KAERI and acquired standard design approval in 2012. SMART works like a pressurized light water reactor in principle though it is more compact than loop type large commercial reactors. ATWS(Anticipated Transient Without Scram) event is an AOO(Anticipated Operational Occurrence) where RPS fails to trip the reactor when requested. SMART incorporated a DPS(diverse protection system) to protect the reactor system when RPS(reactor protection system) fails to trip the reactor. The results of transient analyses show that DPS in SMART effectively mitigates the consequence of ATWS

  5. Linear stochastic differential equations with anticipating initial conditions

    Khalifa, Narjess; Kuo, Hui-Hsiung; Ouerdiane, Habib

    In this paper we use the new stochastic integral introduced by Ayed and Kuo (2008) and the results obtained by Kuo et al. (2012b) to find a solution to a drift-free linear stochastic differential equation with anticipating initial condition. Our solution is based on well-known results from...... classical Itô theory and anticipative Itô formula results from Kue et al. (2012b). We also show that the solution obtained by our method is consistent with the solution obtained by the methods of Malliavin calculus, e.g. Buckdahn and Nualart (1994)....

  6. The anticipation of death by violence: a psychological profile.

    Mahoney, J; Kyle, D; Katz, G

    1975-01-01

    College students (n = 172) completed Cattell's personality factor questionnaire, Rotter's locus of control scale, Speilberger's trait anxiety measure, and Sabatini and Kastenbaum's self-completed death certificate. Comparison of profiles for subjects anticipating sudden violent death (SVD, n = 59) with those anticipating natural death (ND, n = 113) disclosed that the SVD group was characteristically more anxious and socially isolated. A sex-by-type of death interaction occurred for locus of control, with SVD females being the most external, suggesting that this group was more likely to "give up" in response to stress. The data support Shneidman's concept of subintentioned death in disclosing that several personality factors may be associated with violent death.

  7. Potential benefits from the CTBT

    Chang, H.L.

    1999-01-01

    Discussing the potential benefits from the CTBT monitoring in Africa, analysis and data communication systems it was concluded that although yet undeveloped, the possibilities arising from participation in CTBT regime are being identified. The integrated data obtained from the verification technologies of the CTBT should open further horizons for civil society. The main topics of interest are: treaty related science and technology developments, monitoring techniques, ideas and initiatives for expanding existing activities and developing cooperation, including the issues of regional centres and centres of excellence

  8. Victims' use of professional services in a Dutch sexual assault centre

    Bicanic, I.; Snetselaar, H.; de Jongh, A.; van de Putte, E.

    2014-01-01

    Background: Prior research endorsed the establishment of sexual assault centres in the Netherlands because of the potential benefit for victims’ mental recovery. In 2012, the first Dutch sexual assault centre was founded at the University Medical Center Utrecht. The aim of the centre is to provide

  9. Multiple Benefits.

    Kreider, Beth

    1997-01-01

    Discusses the benefits of dome architecture for a community's middle- and high-school multi-purpose facility. The dome construction is revealed as being cost effective in construction and in maintenance and energy costs. (GR)

  10. Energy centre microgrid model

    Pasonen, R.

    2011-09-15

    A simulation model of Energy centre microgrid made with PSCAD simulation software version 4.2.1 has been built in SGEM Smart Grids and Energy Markets (SGEM) work package 6.6. Microgrid is an autonomous electric power system which can operate separate from common distribution system. The idea of energy centre microgrid concept was considered in Master of Science thesis 'Community Microgrid - A Building block of Finnish Smart Grid'. The name of energy centre microgrid comes from a fact that production and storage units are concentrated into a single location, an energy centre. This centre feeds the loads which can be households or industrial loads. Power direction flow on the demand side remains same compared to the current distribution system and allows to the use of standard fuse protection in the system. The model consists of photovoltaic solar array, battery unit, variable frequency boost converter, inverter, isolation transformer and demand side (load) model. The model is capable to automatically switch to islanded mode when there is a fault in outside grid and back to parallel operation mode when fault is removed. The modelled system responses well to load changes and total harmonic distortion related to 50Hz base frequency is kept under 1.5% while operating and feeding passive load. (orig.)

  11. Action preferences and the anticipation of action outcomes

    Mann, D.L.; Schaefers, T.; Canal Bruland, R.

    2014-01-01

    Skilled performers of time-constrained motor actions acquire information about the action preferences of their opponents in an effort to better anticipate the outcome of that opponent's actions. However, there is reason to doubt that knowledge of an opponent's action preferences would unequivocally

  12. Anticipated emotions and effort allocation in weight goal striving.

    Nelissen, Rob M A; de Vet, Emely; Zeelenberg, Marcel

    2011-02-01

    This study aimed to investigate the influence of anticipated emotions on preventive health behaviour if specified at the level of behavioural outcomes. Consistent with predictions from a recently developed model of goal pursuit, we hypothesized that the impact of emotions on effort levels depended on the perceived proximity to the goal. Participants with weight-loss intentions were randomly selected from an Internet panel and completed questionnaires at three points in time, baseline (T1; N= 725), 2 weeks later at T2 (N= 582) and again 2 months later at T3 (N= 528). Questionnaires assessed anticipated emotions (at T1) and experienced emotions (at T2) towards goal attainment and non-attainment. Goal proximity, goal desirability, and effort levels in striving for weight loss were assessed at both T1 and T2. Current and target weights were reported at all three assessments. In line with predictions, we found that negative anticipated emotions towards goal non-attainment resulted in increased effort but only if people perceived themselves in close proximity to their goal. Effort, in turn, predicted weight loss and goal achievement. The current data bear important practical implications as they identify anticipated emotions as targets of behaviour change interventions aimed to stimulate effort in striving for broad, health-related goals like weight loss. ©2010 The British Psychological Society.

  13. Anticipation of complications after laparoscopic cholecystectomy: prediction of individual outcome

    Donkervoort, S. C.; Kortram, K.; Dijksman, L. M.; Boermeester, M. A.; van Ramshorst, B.; Boerma, D.

    2016-01-01

    Complication rates after a laparoscopic cholecystectomy are still up to 10 %. Knowledge of individual patient risk profiles could help to reduce morbidity. The aim of this study is to create risk profiles for specific complications to anticipate on individual outcome. Individual patient outcome for

  14. Evidence of "Implemented Anticipation" in Mathematising by Beginning Modellers

    Stillman, Gloria; Brown, Jill P.

    2014-01-01

    Data from open modelling sessions for year 10 and 11 students at an extracurricular modelling event and from a year 9 class participating in a programme of structured modelling of real situations were analysed for evidence of Niss's theoretical construct, "implemented anticipation," during mathematisation. Evidence was found for all…

  15. ATWS: a reappraisal. Part 3. Frequency of anticipated transients

    McClymont, A.S.; Poehlman, B.W.

    1982-01-01

    This document is the first revision of Part 3 of the EPRI study of the anticipated transients without scram question. This revision includes an update of events at nuclear power plants which had led to fast reactor shutdowns (scrams). The purpose of this document is to present the nuclear power plant operating experience, reflecting the frequency of these events identified by their principal characteristics

  16. Empirical Evidence for Niss' "Implemented Anticipation" in Mathematising Realistic Situations

    Stillman, Gloria; Brown, Jill P.

    2012-01-01

    Mathematisation of realistic situations is an on-going focus of research. Classroom data from a Year 9 class participating in a program of structured modelling of real situations was analysed for evidence of Niss's theoretical construct, implemented anticipation, during mathematisation. Evidence was found for two of three proposed aspects. In…

  17. Looking Forward, Looking Back: Anticipation is More Evocative than Retrospection

    Van Boven, Leaf; Ashworth, Laurence

    2007-01-01

    The results of 5 experiments indicate that people report more intense emotions during anticipation of, than during retrospection about, emotional events that were positive (Thanksgiving Day), negative (annoying noises, menstruation), routine (menstruation), and hypothetical (all-expenses-paid ski vacation). People's tendency to report more intense…

  18. Study of anticipated transient without scram for PWR

    Pu Jilong.

    1985-01-01

    Anticipated Transient Without Scram (ATWS) of PWR, the one of the 'Unresolved Safety Issue' with NRC, has been investigated for many years. The latest analysis done by the author considers the PWR's inherent stability and long-term performence under the condition of ATWS combined with SBLOCA and studies the sensitivity of several assumptions, which shows positive results

  19. The Theoretical Analysis of the Phenomenon of Anticipation in Psychology

    Akhmetzyanova, Anna I.

    2016-01-01

    At the modern stage one of the urgent tasks of development of psychology and pedagogy is the study of the basic directions, trends and developmental priorities of research of the specifics of psychological indicators of anticipation of people with whose mental development corresponds to age norms and persons with intellectual and mental…

  20. Anticipated identification costs: Improving assortment evaluation by diagnostic attributes

    Herpen, van E.; Pieters, F.G.M.

    2007-01-01

    Abstract Consumers often make quick assessments of product assortments, to determine if these are worthwhile for further investigation. They anticipate how difficult it will be to distinguish the various options in the assortment, which will influence their assortment evaluations. We reason that

  1. Liturgy as space for anticipation | Cilliers | HTS Teologiese Studies ...

    This article proposes that the notion of liturgical space, understood in conjunction with the original Greek concept of space, is not only a quantitative, physical locality, but also a primary qualitative possibility for existence, a meaningful womb, a neighbourhood for imagination and a space for anticipation.

  2. Conservatives Anticipate and Experience Stronger Emotional Reactions to Negative Outcomes.

    Joel, Samantha; Burton, Caitlin M; Plaks, Jason E

    2014-02-01

    The present work examined whether conservatives and liberals differ in their anticipation of their own emotional reactions to negative events. In two studies, participants imagined experiencing positive or negative outcomes in domains that do not directly concern politics. In Study 1, 190 American participants recruited online (64 male, Mage  = 32 years) anticipated their emotional responses to romantic relationship outcomes. In Study 2, 97 Canadian undergraduate students (26 male, Mage  = 21 years) reported on their anticipated and experienced emotional responses to academic outcomes. In both studies, more conservative participants predicted they would feel stronger negative emotions following negative outcomes than did more liberal participants. Furthermore, a longitudinal follow-up of Study 2 participants revealed that more conservative participants actually felt worse than more liberal participants after receiving a lower-than-desired exam grade. These effects remained even when controlling for the Big Five traits, prevention focus, and attachment style (Study 1), and optimism (Study 2). We discuss how the relationship between political orientation and anticipated affect likely contributes to differences between conservatives and liberals in styles of decision and policy choices. © 2013 Wiley Periodicals, Inc.

  3. Anticipated emotions and effort allocation in weight goal striving

    Nelissen, R.M.A.; de Vet, H.C.W.; Zeelenberg, M.

    2011-01-01

    Objective. This study aimed to investigate the influence of anticipated emotions on preventive health behaviour if specified at the level of behavioural outcomes. Consistent with predictions from a recently developed model of goal pursuit, we hypothesized that the impact of emotions on effort levels

  4. Person x Context Effects on Anticipated Moral Emotions Following Aggression

    Roos, Sanna; Salmivalli, Christina; Hodges, Ernest V. E.

    2011-01-01

    We investigated person (sex, aggression level), context (witness type, victim reactions), and person x context effects on children's anticipated moral emotions following hypothetical acts of aggression against a peer. Children (N = 378, mean age = 11.3 years) were presented a series of hypothetical vignettes in which the presence of witnesses (no…

  5. The Axiomatic Basis of Anticipated Utility: A Clarification

    J. Quiggin (John); P.P. Wakker (Peter)

    1994-01-01

    textabstractQuiggin (J. Econ. Behav. Organization3 (1982), 323-345) introduced anticipated ("rank-dependent") utility theory into decision making under risk. Questions have been raised about mathematical aspects of Quiggin′s analysis. This paper settles these questions and shows that a minor

  6. Anticipated Work-Family Conflict: A Construct Investigation

    Westring, Alyssa Friede; Ryan, Ann Marie

    2011-01-01

    To date, little is known about how work-family issues impact the career development process. In the current paper, we explore this issue by investigating a relatively unstudied construct: anticipated work-family conflict. We found that this construct can be represented by the same six-dimensional factor structure used to assess concurrent…

  7. Force-induced chemical reactions on the metal centre in a single metalloprotein molecule

    Zheng, Peng; Arantes, Guilherme M.; Field, Martin J.; Li, Hongbin

    2015-01-01

    Metalloproteins play indispensable roles in biology owing to the versatile chemical reactivity of metal centres. However, studying their reactivity in many metalloproteins is challenging, as protein three-dimensional structure encloses labile metal centres, thus limiting their access to reactants and impeding direct measurements. Here we demonstrate the use of single-molecule atomic force microscopy to induce partial unfolding to expose metal centres in metalloproteins to aqueous solution, thus allowing for studying their chemical reactivity in aqueous solution for the first time. As a proof-of-principle, we demonstrate two chemical reactions for the FeS4 centre in rubredoxin: electrophilic protonation and nucleophilic ligand substitution. Our results show that protonation and ligand substitution result in mechanical destabilization of the FeS4 centre. Quantum chemical calculations corroborated experimental results and revealed detailed reaction mechanisms. We anticipate that this novel approach will provide insights into chemical reactivity of metal centres in metalloproteins under biologically more relevant conditions. PMID:26108369

  8. The ideal Atomic Centre

    Mas, R.

    1965-01-01

    The author presents considerations which should prove to be of interest to all those who have to design, to construct and to operate a nuclear research centre. A large number of the ideas presented can also be applied to non-nuclear scientific research centres. In his report the author reviews: various problems with which the constructor is faced: ground-plan, infrastructure, buildings and the large units of scientific equipment in the centre, and those problems facing the director: maintenance, production, supplies, security. The author stresses the relationship which ought to exist between the research workers and the management. With this aim in view he proposes the creation of National School for Administration in Research which would train administrative executives for public or private organisations; they would be specialised in the fields of fundamental or applied research. (author) [fr

  9. The Canadian Centre for Nuclear Innovation

    Root, J., E-mail: John.Root@usask.ca [Canadian Centre for Nuclear Innovation, Inc., Saskatoon, Saskatchewan (Canada)

    2013-07-01

    The Canadian Centre for Nuclear Innovation (CCNI) was incorporated on December 20, 2011, to help place Saskatchewan among global leaders of nuclear research, development and training, through investment in partnerships with academia and industry for maximum societal and economic benefit. As the CCNI builds a community of participants in the nuclear sector, the province of Saskatchewan expects to see positive impacts in nuclear medicine, materials research, nuclear energy, environmental responsibility and the quality of social policy related to nuclear science and technology. (author)

  10. Netherlands Reactor Centre

    Anon.

    1976-01-01

    Briefly reviews the last year's work of the twenty year old Netherlands Reactor Centre (RCN) in the fields of reactor safety, fissile material, nuclear fission, non-nuclear energy systems and overseas co-operation. The annual report thus summarised is the last one to appear under the name of RCN. The terms of reference of the organisation having been broadened to include research into energy supply in general, it is to be known in future as the Netherlands Energy Research Centre (ECN). (D.J.B.)

  11. The Structural Integrity Centre

    Tomkins, B.

    1987-01-01

    The paper concerns the development and work of the Structural Integrity Centre (SIC) at Risley Nuclear Laboratories, United Kingdom. The centre was set up to provide authoritative advice to plant designers and operators on the integrity and life assessment of structures and components across the reactor projects in the United Kingdom. A description is given of the structure and role of the SIC, as well as the Structural Integrity Assessment work. The assessment methods are described for thermally loaded structures and welded structures. Finally, defect significance assessment and environmental effects are outlined. (U.K.)

  12. Parental regret regarding children's vaccines-The correlation between anticipated regret, altruism, coping strategies and attitudes toward vaccines.

    Hamama-Raz, Yaira; Ginossar-David, Eyal; Ben-Ezra, Menachem

    2016-01-01

    Parental hesitancy for recommended childhood vaccines is a growing public health concern influenced by various factors. This study aimed to explore regret regarding parental decisions to vaccinate their children via possible correlations between anticipated regret, altruism, coping strategies, and parents' attitudes toward the vaccination of their children. The study was conducted during 2014 in Israel. Data were collected via snowballing methodology (i.e., Internet forums, Facebook and e- mails). 314 parents of children ages 0-6 years participated in the study. Questionnaires were distributed and completed on-line including attitudes toward vaccines, altruism, coping strategies, regret and anticipated regret. Pearson analysis revealed a moderate negative association between attitudes toward vaccinations and regret. In addition, weak but significant positive associations emerged between anticipated regret and regret as well as between gender and regret. Performing hierarchical regression analysis revealed contribution of 35.9 % to the explained variance of regret suggesting that coping strategy of instrumental support, attitudes toward vaccinations and anticipated regret are linked significantly to regret. Parental attitudes toward vaccines and anticipated regret have a salient role when deciding whether or not to vaccinate children and contribute to the prediction of regret regarding vaccination. In order to increase parental consent to vaccination of their children, it is important to minimize possible regret through the strength of the recommendation and/or knowledge base about risk/benefit (perceived, heuristic) of vaccines that might influence parental attitudes and lessen their anticipated regret. N/A. This is not a clinical trial and thus does not require registration. Ethics approval was received from Ariel University School of Social Work Ethics committee (18/02/14). This was an attitude survey. The Ariel University School of Social Work Ethics committee

  13. International research centre launched

    1965-01-01

    Full text: The first scientific research and educational institution to be set up on a completely international basis was officially inaugurated in Trieste on 5 October 1964 by the Director General of IAEA, Dr. Sigvard Eklund, when he opened the first seminar of the International Centre for Theoretical Physics. As evidence of the international nature of the institution he noted that the scientists who would work and teach there during the first year represented sixteen different countries. By the end of 1964, the Centre building was nearing completion and three of the five floors were occupied. A successful symposium had been held on the subject of plasma physics, and a score of professors and fellows were at work, from Bulgaria, Czechoslovakia, Greece, India, Japan, Jordan, the Netherlands, Norway, Pakistan, Poland, the United Kingdom, and the United States. A dozen scientific papers had been issued as preprints. The main purpose of the Centre is to foster the advancement of theoretical physics through training and research; at first the chief subject will be high-energy and elementary particle physics. Plasma physics, low energy physics and solid-state physics will also be dealt with. Special attention is paid to the needs of the developing countries. Of the 25 fellows selected for the academic year 1964-65, more than half are from South America, Africa and Asia. In conjunction with the Research Centre, there is an Advanced School for theoretical Physics to provide graduate training for fellows who need such preparation before they embark upon research. The Centre works under the guidance of a Scientific Council comprising the president, Prof. M. Sandoval-Vallarta (Nuclear Energy Commission of Mexico); Prof. A. Abragam (Saclay, France); Prof. R. Oppenheimer (Institute for Advanced Study, Princeton, USA); Dr. V. Soloviev (Dubna, USSR); Prof V.F. Weiskopf (Director General, CERN) ; Prof Abdus Salam (Imperial College, London) ; Prof. P. Budini (University of Trieste

  14. Centre for Political and

    user

    and definitions will be published and the data translated into the official ... The Centre provides a terminological and subject-related service to lecturers and ... postgraduate students in international politics, political studies and .... obtain financial contributions (cf. .... making of authoritative and enforceable rules (laws) for.

  15. Implementing Responsibility Centre Budgeting

    Vonasek, Joseph

    2011-01-01

    Recently, institutes of higher education (universities) have shown a renewed interest in organisational structures and operating methodologies that generate productivity and innovation; responsibility centre budgeting (RCB) is one such process. This paper describes the underlying principles constituting RCB, its origin and structural elements, and…

  16. Budapest Training Technology Centre.

    Budapest Training Technology Centre (Hungary).

    The Budapest Training Technology Centre (BTTC) grew out of a 1990 agreement calling for Great Britain to help Hungary develop and implement open and flexible training methods and technology-based training to support the labor force development and vocational training needs resulting from Hungary's transition to a market economy. The BTTC would be…

  17. Official Centre Hospitality

    Sylvain Dufour

    Approved by the Management Executive Committee. - 1 -. Version 3.1.0 effective 2017-06-28. Official Centre Hospitality. 1. Objective. 2. Application. 3. Definitions. 4. Roles and Responsibilities. 5. Authorization. 6. Consultants and Contractors. 7. Reimbursement. 1. Objective. To define the circumstances under which ...

  18. Academic Drug Discovery Centres

    Kirkegaard, Henriette Schultz; Valentin, Finn

    2014-01-01

    Academic drug discovery centres (ADDCs) are seen as one of the solutions to fill the innovation gap in early drug discovery, which has proven challenging for previous organisational models. Prior studies of ADDCs have identified the need to analyse them from the angle of their economic...

  19. ATLAS Visitors Centre

    claudia Marcelloni

    2009-01-01

    ATLAS Visitors Centre has opened its shiny new doors to the public. Officially launched on Monday February 23rd, 2009, the permanent exhibition at Point 1 was conceived as a tour resource for ATLAS guides, and as a way to preserve the public’s opportunity to get a close-up look at the experiment in action when the cavern is sealed.

  20. Benefits | NREL

    flexible work environment that enables and encourages a good work/life balance A growing, changing exceptional work. A woman riding her bike past the NREL entrance sign. Hundreds of NREL employees opt out of their cars, cycling to work, to take part in Bike To Work Day each year. Benefits Package NREL's

  1. Fringe Benefits.

    Podgursky, Michael

    2003-01-01

    Uses statistics from the National Center for Education Statistics and the Bureau of Labor Statistics to examine teacher salaries and benefits. Discusses compensation of teachers compared with nonteachers. Asserts that statistics from the American Federation of Teachers and the National Education Association underestimate teacher compensation…

  2. Pramipexole modulates the neural network of reward anticipation.

    Ye, Zheng; Hammer, Anke; Camara, Estela; Münte, Thomas F

    2011-05-01

    Pramipexole is widely prescribed to treat Parkinson's disease. It has been found to cause impulse control disorders such as pathological gambling. To examine how pramipexole modulates the network of reward anticipation, we carried out a pharmacological functional magnetic resonance imaging study with a double-blind, within-subject design. During the anticipation of monetary rewards, pramipexole increased the activity of the nucleus accumbens (NAcc), enhanced the interaction between the NAcc and the anterior insula, but weakened the interaction between the NAcc and the prefrontal cortex. These results suggest that pramipexole may exaggerate incentive and affective responses to possible rewards, but reduce the top-down control of impulses, leading to an increase in impulsive behaviors. This imbalance between the prefrontal-striatum connectivity and the insula-striatum connectivity may represent the neural mechanism of pathological gambling caused by pramipexole. Copyright © 2010 Wiley-Liss, Inc.

  3. Leveraging management information in improving call centre productivity

    Manthisana Mosese

    2016-04-01

    Objectives: This research explored the use of management information and its impact on two fundamental functions namely, improving productivity without compromising the quality of service, in the call centre of a well-known South African fashion retailer, Edcon. Following the implementation of the call centre technology project the research set out to determine how Edcon can transform their call centre to improve productivity and customer service through effective utilisation of their management information. Method: Internal documents and reports were analysed to provide the basis of evaluation between the measures of productivity prior to and post the implementation of a technology project at Edcon’s call centre. Semi-structured in-depth and group interviews were conducted to establish the importance and use of management information in improving productivity and customer service. Results: The results indicated that the availability of management information has indeed contributed to improved efficiency at the Edcon call centre. Although literature claims that there is a correlation between a call centre technology upgrade and improvement in performance, evident in the return on investment being realised within a year or two of implementation, it fell beyond the scope of this study to investigate the return on investment for Edcon’s call centre. Conclusion: Although Edcon has begun realising benefits in improved productivity in their call centre from their available management information, information will continue to play a crucial role in supporting management with informed decisions that will improve the call centre operations. [pdf to follow

  4. Exceptional maintenance and anticipation. Hazard detection and processing methodology

    Nicot, P.; Mesnage, J.

    1994-01-01

    In order to minimize the consequences of important problems on nuclear reactor equipment, the basic principle to be applied is anticipation, which concerns the development of methods and tools and the related preventive actions. The example of the reactor vessel cover leakage problem in 1991, and its resolution, has led to a control, detection and replacement-to-survey strategy. Thus, a preventive industrial awareness strategy has been implemented for predictable and unpredictable problems

  5. A review on Anticipated Breakthrough Technologies of 21st Century

    Aithal P. S.; Shubhrajyotsna Aithal

    2016-01-01

    This review discuss strategic management of thirteen most anticipated possible technology breakthroughs of 21st century which are substantially affect the life style of living beings in the world like (1) Nanotechnology-based human life comfort, (2) High speed computation through optical computers, (3) Embedded Intelligence, (4) HIV Antivirus, (5) Pseudo Senses - Sensation of existence through virtual reality and through artificial environment, (6) Off Planet Production in micro-gravity, (7) ...

  6. Anticipating requirements changes-using futurology in requirements elicitation

    Pimentel, João Henrique; Santos, Emanuel; Castro, Jaelson; Franch Gutiérrez, Javier

    2012-01-01

    It is well known that requirements changes in a later phase of software developments is a major source of software defects and costs. Thus, the need of techniques to control or reduce the amount of changes during software development projects. The authors advocate the use of foresight methods as a valuable input to requirements elicitation, with the potential to decrease the number of changes that would be required after deployment, by anticipating them. In this paper, the authors define a pr...

  7. Network Organization Unfolds over Time during Periods of Anxious Anticipation

    McMenamin, Brenton W.; Langeslag, Sandra J.E.; Sirbu, Mihai; Padmala, Srikanth; Pessoa, Luiz

    2014-01-01

    Entering a state of anxious anticipation triggers widespread changes across large-scale networks in the brain. The temporal aspects of this transition into an anxious state are poorly understood. To address this question, an instructed threat of shock paradigm was used while recording functional MRI in humans to measure how activation and functional connectivity change over time across the salience, executive, and task-negative networks and how they interact with key regions implicated in emo...

  8. Anticipating WPS PIN Vulnerability to Secure Wireless Network

    Indra Dwi Rianto

    2013-12-01

    Full Text Available WiFi Protected Setup (WPS is a standardized function supported by numerous vendors of wireless routers and access point to help set up connection to a wireless local area network. It is designed to simplify the set up and generally enabled by default. Due to design flaw, the WPS or QSS PIN is susceptible to a brute forceattack. In this paper, we test the security vulnerability occurred, evaluate the performance and give recommendations to anticipate the attack.

  9. [Precarity, vulnerability, anticipating end-of-life care at home].

    Bonneval, Camille

    2016-02-01

    Many patients want to end their life at home. Care teams adapt to these wishes and organise a form of treatment which blends safety of care and the respect of the expectations of the patients and family members. When factors of precarity increase the vulnerability inherent to the end of life, caregivers anticipate and support as best as they can the difficulties encountered as testified by a hospital at home team in Dax. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  10. Early event related fields during visually evoked pain anticipation.

    Gopalakrishnan, Raghavan; Burgess, Richard C; Plow, Ela B; Floden, Darlene P; Machado, Andre G

    2016-03-01

    Pain experience is not only a function of somatosensory inputs. Rather, it is strongly influenced by cognitive and affective pathways. Pain anticipatory phenomena, an important limitation to rehabilitative efforts in the chronic state, are processed by associative and limbic networks, along with primary sensory cortices. Characterization of neurophysiological correlates of pain anticipation, particularly during very early stages of neural processing is critical for development of therapeutic interventions. Here, we utilized magnetoencephalography to study early event-related fields (ERFs) in healthy subjects exposed to a 3 s visual countdown task that preceded a painful stimulus, a non-painful stimulus or no stimulus. We found that the first countdown cue, but not the last cue, evoked critical ERFs signaling anticipation, attention and alertness to the noxious stimuli. Further, we found that P2 and N2 components were significantly different in response to first-cues that signaled incoming painful stimuli when compared to non-painful or no stimuli. The findings indicate that early ERFs are relevant neural substrates of pain anticipatory phenomena and could be potentially serve as biomarkers. These measures could assist in the development of neurostimulation approaches aimed at curbing the negative effects of pain anticipation during rehabilitation. Copyright © 2015 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  11. The ADaptation and Anticipation Model (ADAM) of sensorimotor synchronization

    van der Steen, M. C. (Marieke); Keller, Peter E.

    2013-01-01

    A constantly changing environment requires precise yet flexible timing of movements. Sensorimotor synchronization (SMS)—the temporal coordination of an action with events in a predictable external rhythm—is a fundamental human skill that contributes to optimal sensory-motor control in daily life. A large body of research related to SMS has focused on adaptive error correction mechanisms that support the synchronization of periodic movements (e.g., finger taps) with events in regular pacing sequences. The results of recent studies additionally highlight the importance of anticipatory mechanisms that support temporal prediction in the context of SMS with sequences that contain tempo changes. To investigate the role of adaptation and anticipatory mechanisms in SMS we introduce ADAM: an ADaptation and Anticipation Model. ADAM combines reactive error correction processes (adaptation) with predictive temporal extrapolation processes (anticipation) inspired by the computational neuroscience concept of internal models. The combination of simulations and experimental manipulations based on ADAM creates a novel and promising approach for exploring adaptation and anticipation in SMS. The current paper describes the conceptual basis and architecture of ADAM. PMID:23772211

  12. Health, Anticipated Partner Infidelity, and Jealousy in Men and Women

    Steven Arnocky

    2015-07-01

    Full Text Available Health has been identified as an important variable involved in mate choice. Unhealthy organisms are generally less able to provide reproductively important resources to partners and offspring and are more likely to pass on communicable disease. Research on human mate preferences has shown that both men and women prefer healthy mates. Yet to date, little research has examined how health relates to one’s own mating experiences. In the present study, 164 participants (87 women who were currently in heterosexual romantic relationships completed measures of frequency and severity of health problems, anticipated partner infidelity, and intensity of jealousy felt in their current relationship. Mediation analyses showed that health problems predicted greater anticipated partner infidelity and jealousy scores and that anticipated partner infidelity mediated the links between health and jealousy for both frequency and severity of health problems, controlling for both sex and relationship duration. These findings suggest that unhealthy people perceive themselves to be at a mating disadvantage, experiencing associated differences in perceptions and emotions surrounding their romantic partners’ fidelity.

  13. Anticipating Early Fatality: Friends', Schoolmates' and Individual Perceptions of Fatality on Adolescent Risk Behaviors

    Soller, Brian; Williams, Kristi

    2015-01-01

    Past research indicates that anticipating adverse outcomes, such as early death (fatalism), is associated positively with adolescents' likelihood of engaging in risky behaviors. Health researchers and criminologists have argued that fatalism influences present risk taking in part by informing individuals' motivation for delaying gratification for the promise of future benefits. While past findings highlight the association between the anticipation of early death and a number of developmental outcomes, no known research has assessed the impact of location in a context characterized by high perceptions of fatality. Using data from Add Health and a sample of 9,584 adolescents (51 % female and 71 % white) nested in 113 schools, our study builds upon prior research by examining the association between friends', school mates', and individual perceptions of early fatality and adolescent risk behaviors. We test whether friends' anticipation of being killed prior to age 21 or location in a school where a high proportion of the student body subscribes to attitudes of high fatality, is associated with risky behaviors. Results indicate that friends' fatalism is positively associated with engaging in violent delinquency, non-violent delinquency, and drug use after controlling for individual covariates and prior individual risk-taking. Although friends' delinquency accounts for much of the effect of friends' fatalism on violence, none of the potential intervening variables fully explain the effect of friends' fatalism on youth involvement in nonviolent delinquency and drug use. Our results underscore the importance of friendship contextual effects in shaping adolescent risk-taking behavior and the very serious consequences perceptions of fatality have for adolescents' involvement in delinquency and drug use. PMID:23828725

  14. Extending cost–benefit analysis for the sustainability impact of inter-urban Intelligent Transport Systems

    Kolosz, Ben; Grant-Muller, Susan

    2015-01-01

    The paper reports research involving three cost–benefit analyses performed on different ITS schemes (Active Traffic Management, Intelligent Speed Adaptation and the Automated Highway System) on one of the UK's busiest highways — the M42. The environmental scope of the assets involved is widened to take into account the possibility of new technology linked by ICT and located within multiple spatial regions. The areas focused on in the study were data centre energy emissions, the embedded emissions of the road-side infrastructure, vehicle tailpipe emissions, additional hardware required by the vehicles (if applicable) and safety, and all aspects of sustainability. Dual discounting is applied which aims to provide a separate discount rate for environmental elements. For ATM, despite the energy costs of the data centre, the initial implementation costs and mitigation costs of its embedded emissions, a high cost–benefit ratio of 5.89 is achieved, although the scheme becomes less effective later on its lifecycle due to rising costs of energy. ISA and AHS generate a negative result, mainly due to the cost of getting the vehicle on the road. In order to negate these costs, the pricing of the vehicle should be scaled depending upon the technology that is outfitted. Retrofitting on vehicles without the technology should be paid for by the driver. ATM will offset greenhouse gas emissions by 99 kt of CO 2 equivalency over a 25 year lifespan. This reduction has taken into account the expected improvement in vehicle technology. AHS is anticipated to save 280 kt of CO 2 equivalency over 15 years of operational usage. However, this offset is largely dependent on assumptions such as the level of market penetration. - Highlights: • Three cost–benefit analyses are applied to inter-urban intelligent transport. • For ATM, a high cost–benefit ratio of 5.89 is achieved. • ATM offsets greenhouse gas emissions by 99 kt of CO 2 equivalency over 25 years. • ISA and AHS

  15. Extending cost–benefit analysis for the sustainability impact of inter-urban Intelligent Transport Systems

    Kolosz, Ben, E-mail: kolosz27@gmail.com; Grant-Muller, Susan, E-mail: S.M.Grant-Muller@its.leeds.ac.uk

    2015-01-15

    The paper reports research involving three cost–benefit analyses performed on different ITS schemes (Active Traffic Management, Intelligent Speed Adaptation and the Automated Highway System) on one of the UK's busiest highways — the M42. The environmental scope of the assets involved is widened to take into account the possibility of new technology linked by ICT and located within multiple spatial regions. The areas focused on in the study were data centre energy emissions, the embedded emissions of the road-side infrastructure, vehicle tailpipe emissions, additional hardware required by the vehicles (if applicable) and safety, and all aspects of sustainability. Dual discounting is applied which aims to provide a separate discount rate for environmental elements. For ATM, despite the energy costs of the data centre, the initial implementation costs and mitigation costs of its embedded emissions, a high cost–benefit ratio of 5.89 is achieved, although the scheme becomes less effective later on its lifecycle due to rising costs of energy. ISA and AHS generate a negative result, mainly due to the cost of getting the vehicle on the road. In order to negate these costs, the pricing of the vehicle should be scaled depending upon the technology that is outfitted. Retrofitting on vehicles without the technology should be paid for by the driver. ATM will offset greenhouse gas emissions by 99 kt of CO{sub 2} equivalency over a 25 year lifespan. This reduction has taken into account the expected improvement in vehicle technology. AHS is anticipated to save 280 kt of CO{sub 2} equivalency over 15 years of operational usage. However, this offset is largely dependent on assumptions such as the level of market penetration. - Highlights: • Three cost–benefit analyses are applied to inter-urban intelligent transport. • For ATM, a high cost–benefit ratio of 5.89 is achieved. • ATM offsets greenhouse gas emissions by 99 kt of CO{sub 2} equivalency over 25 years

  16. Who benefits?

    Hjorth, Frederik Georg

    2016-01-01

    Cross-border welfare rights for citizens of European Union member states are intensely contested, yet there is limited research into voter opposition to such rights, sometimes denoted ‘welfare chauvinism’. We highlight an overlooked aspect in scholarly work: the role of stereotypes about benefici...... recipient identity. These effects are strongest among respondents high in ethnic prejudice and economic conservatism. The findings imply that stereotypes about who benefits from cross-border welfare rights condition public support for those rights....

  17. Self-care and anticipated transition into retirement and later life in a Nordic welfare context

    Söderhamn O

    2011-07-01

    Full Text Available Olle Söderhamn1–3, Anne Skisland1,2, Margaretha Herrman31Department of Health and Nursing Sciences, Faculty of Health and Sport Sciences, University of Agder, Grimstad and Kristiansand, Norway; 2Centre for Caring Research – Southern Norway, Grimstad, Norway; 3Department of Nursing, Health and Culture, University West, Trollhättan, SwedenAbstract: Few studies have appeared in the health care literature on the meaning of transition into retirement and later life. However, this predictable-involuntary transition may influence personal health and well-being, and studying it from a self-care perspective could be useful. The aim of this study was to illuminate aspects of self-care in a group of middle-aged individuals in relation to their anticipated transition into retirement in the Nordic welfare context. A total of 13 individuals, aged 55 to 65 years, were randomly chosen from the total number of inhabitants in three municipalities in mid-west Sweden. Conversational interviews took place, during which the informants shared important events in their lives that had occurred from early childhood until the present time, together with thoughts about their anticipated future developmental transition into later life. The interviews were tape recorded and transcribed verbatim. After content analyses and interpretation, a comprehensive picture of the phenomenon was revealed. The results showed that there were opportunities, expectations, wishes, concerns, and worries related to the transition into retirement and old age among informants from both rural and urban municipalities. Self-care, in connection with this, depended on motivating and demotivating factors. Autonomy and mature dependence seemed to be positive driving forces for reaching a successful transition into later life. Supporting autonomy should be a way of facilitating the transition into retirement and later life.Keywords: aging, autonomy, motivation, older people, successful aging

  18. Elderly Care Centre

    Wagiman, Aliani; Haja Bava Mohidin, Hazrina; Ismail, Alice Sabrina

    2016-02-01

    The demand for elderly centre has increased tremendously abreast with the world demographic change as the number of senior citizens rose in the 21st century. This has become one of the most crucial problems of today's era. As the world progress into modernity, more and more people are occupied with daily work causing the senior citizens to lose the care that they actually need. This paper seeks to elucidate the best possible design of an elderly care centre with new approach in order to provide the best service for them by analysing their needs and suitable activities that could elevate their quality of life. All these findings will then be incorporated into design solutions so as to enhance the living environment for the elderly especially in Malaysian context.

  19. Five-Year-Old Preschoolers' Sharing is Influenced by Anticipated Reciprocation.

    Xiong, Mingrui; Shi, Jiannong; Wu, Zhen; Zhang, Zhen

    2016-01-01

    Whether children share in anticipation of future benefits returned by a partner is an interesting question. In this study, 5-year-old children and an adult partner played a sharing game, in which children donated first and the partner donated afterward. In Experiment 1, the partner's resources were more attractive than the child's. In the reciprocal condition, the child was told that s/he would be a recipient when the partner played as a donor. In the non-reciprocal condition, however, the child was told that an anonymous child would be the recipient when the partner donated. Results showed that children shared more with the partner when they knew that they would be a recipient later. In Experiment 2, the child was always the recipient when the partner donated, but the partner's resources were more desirable than the child's in the high-value condition, and less desirable in the low-value condition. We found that children were more generous when the partner's resources were valued higher. These findings demonstrate that 5-year-old preschoolers' sharing choices take into account the anticipated reciprocity of the recipient, suggesting either self-interested tactical sharing or direct reciprocity in advance of receiving. Specifically, they adjust their sharing behavior depending on whether a partner has the potential to reciprocate, and whether it is worth sharing relative to the value of the payback.

  20. International Data Centre (IDC)

    Johansson, P.

    2002-01-01

    The presentation outlines the International Data Centre (Indc) mission, objective and historical background. The Indc progressive commissioning and organizational plans are presented on charts. The IMS stations providing data to Indc operations and the global communication infrastructure are plotted on world maps. The various types of IMS data are thus listed as seismic, hydroacoustic, infrasound and radionuclide. Finally Indc products and services together with its main achievements are listed

  1. Historical centres: changing definitions

    Roberta Lazzarotti

    2014-02-01

    Full Text Available Since the end of the Second World War, the architectural and planning culture has been showing a fluctuating attention to the theme of historical centres and their enhancement. First of all this uneven progress explains the difficulty to reach a homogeneous definition and this is still lacking. During a long phase of this period, the historical parts of the town were considered as objects to be preserved in an integral way, as urban monuments. This is mostly due to the high symbolic value of these settlements, that represent fundamental landmarks. Identity building and empowerment of local communities are indispensable conditions for any development programme, especially in the case of centres or other historic environments at risk of abandonment. The progressive evolution of this concept brings awareness of the impossibility of separating – either in analytical or in planning terms ­ historical centres from their urban and territorial contexts, which are linked by mutual, deep relationships. This article attempts to retrace the steps signaled by the publication of international documents and conventions, from the Charter of Gubbio (1960 to the Charter of Krakow and the European Landscape Convention (2000; they obviously represent particular points of view, not exhaustive of the richness of the positions in the debate, but extremely significant in terms of diffusion and consensus.

  2. Low energy use at Vaestervik sports centre

    2009-05-15

    Vaestervik, in south Sweden, has saved both energy and money since modern energy efficiency equipment was installed in its swimming pool and bowling alley. Energy use in the sports centre has so far fallen by around 830 MWh/year, and operating costs have been reduced by efficient heat recovery. Energy efficiency at the Vaestervik sports centre is a good example of how a local authority can save energy and money by installing modern equipment for ventilation and heat recovery in a facility with high energy consumption. The well-used sports centre, including a swimming pool and bowling alley, is in central Vaestervik. In 1999 the Municipality received grants from the local investment programme (LIP) to improve the facility's energy efficiency. An efficient ventilation system with a dehumidifier and heat exchanger was installed at the swimming pool, reducing the need to introduce cold air. In addition the bowling alley, which did not have heat recovery, was given a modern heat-recovery plant. - Lower operating costs due to efficient heat recovery. - Reduced energy use (electricity and district heating) for the plant at around 830 MWh/year. The modern and highly efficient units for heat recovery, dehumidification and heat exchange result in lower operating costs and reduced energy use, which means that the Municipality of Vaestervik saves energy and money. Installation at the swimming pool resulted in slightly higher air humidity, but a relative humidity of 60% is common in swimming pools and difficult to reduce without inconveniencing bathers. A new fan room installed in the roof contributed to higher than anticipated costs, but the financial and economic gains outweigh these. New frequency-controlled circulation pumps for the pool water were installed in 2007. They are to have occupancy control capability, giving a further improvement of energy saving and heat recovery

  3. The CERN Control Centre is up and running!

    2006-01-01

    The CERN Control Centre (CCC) that combines all the control rooms for the accelerators, the cryogenic system and the technical infrastructure came into operation on 1st February. This is not a mock-up but the real thing! The CERN Control Centre has been built and put into operation in only 15 months.On 1st February, at 2.00 p.m., Patrick Villeton Pachot started the first Technical Infrastructure shift at the brand new CERN Control Centre. From now on, when you dial 72201 to report a leak or an electrical fault, your call will ring out in the brand new CERN Control Centre. The much anticipated CCC came on line on 1st February, exactly as planned. The 2.00 p.m. shift by the operators of the former Technical Control Room (TCR), now renamed TI for Technical Infrastructure, marked the start of operations at the Centre. The PCR, MCR, TCR and QCR are no more, and all the individual control rooms have been merged into one. And what a control room it is! True to the streamlined image announced when the project was f...

  4. Anticipating the use of future things: towards a framework for prospective use analysis in innovation design projects.

    Nelson, Julien; Buisine, Stéphanie; Aoussat, Améziane

    2013-11-01

    Anticipation of future product use is a persistent issue in User-Centered Design. In this paper, we argue that one obstacle to early integration of use analysis in innovation design is overreliance on retrospective use analysis, i.e. that which is based on clear references to existing products or activities. In contrast, innovation design projects are full of uncertainty, leading to a need for prospective analysis. After having described some limitations of prospective use analysis, we contend that creativity tools may be used to assist the anticipation of future product use, by allowing designers to approach the variability of situations of future use in a structured manner rather than by "muddling through". We illustrate the expected benefits of this approach with two case studies, and describe some prospects for future research and practice in ergonomics. Copyright © 2013. Published by Elsevier Ltd.

  5. Hi-Tech Skills Anticipation for Sustainable Development in Russia

    Valery Gurtov

    2014-12-01

    Full Text Available It is evident that there is a heightened importance in Russia attributed to ensuring that students develop skills, which will enable them to be more productive and engaged citizens. This article deals with a skills anticipation methodology for seven hi-tech industries in Russia that resulted in the development of models for both soft and hard skills. There is a variety of widely applied methods – qualitative projection of labor market parameters, desk studies, documents analysis, foresight sessions, employers' and experts' surveys. As a result, new skills models are to help the specialists to effectively overcome the challenges, apply innovative decisions, and increase their technological knowledge.

  6. Anticipation of dental anomalies induced by radiation therapy

    Guggenheimer, J.; Fischer, W.G.; Pechersky, J.L.

    1975-01-01

    Therapeutic irradiation of the head and neck of children up to the age of 16 years can cause malformation and developmental arrest of the permanent teeth. Dental anomalies occurring after irradiation of the palatal tumor in an 8-year-old are described and compared with a normal 8-year-old's developmental sequence to demonstrate that the immature, noncalcified dental structures are most susceptible to radiation injury. The stage of dental development at the time of therapy may be precisely determined by a routine oral radiographic survey, which provides a reliable estimate of the deformation that may be anticipated following radiotherapy. (auth)

  7. A parametric model for analyzing anticipation in genetically predisposed families

    Larsen, Klaus; Petersen, Janne; Bernstein, Inge

    2009-01-01

    and are sensitive to right truncation of the data. We propose a normal random effects model that allows for right-censored observations and includes covariates, and draw statistical inference based on the likelihood function. We applied the model to the hereditary nonpolyposis colorectal cancer (HNPCC)/Lynch...... syndrome family cohort from the national Danish HNPCC register. Age-at-onset was analyzed in 824 individuals from 2-4 generations in 125 families with proved disease-predisposing mutations. A significant effect from anticipation was identified with a mean of 3 years earlier age-at-onset per generation...

  8. DGNB certified Healthcare Centres

    Brunsgaard, Camilla; Larsen, Tine Steen

    2015-01-01

    for sustainability and wants a certification. This research investigates the decision‐making and design process (DMaDP) behind four DGNB certified Healthcare Centres (HCC) in Northern Jutland in Denmark. In general, knowledge about the DMaDP is important. However it is important to know what part DGNB plays...... a dialog about DGNB and energy concept is important even before anyone start sketching. Experiences with the different approaches will be further outlined in the paper.Future research has the intention to collect further knowledge about DGNB and DMaDP in practise. This project was limited to Healthcare...

  9. Town Centre Redevelopment Strategies

    Vagnby, Bo Hellisen

    After many years of urban growth Danish downtowns are facing some important choices. Shall the stake one-sidedly be on the town centres as driving forces for growth and 'city marketing', or do they still have a role to play in a broader socio-economic context? In the paper we look back on eight...... as slum clearence and urban renewal. To a certain extent parallels are drawn to international experiences, especially where these are of such a nature that they can be assumed transferred to Danish connctions. Conclusively, the strategies are discussed in the light of the turn of Danish urban planning...

  10. Children's schemes for anticipating the validity of nets for solids

    Wright, Vince; Smith, Ken

    2017-09-01

    There is growing acknowledgement of the importance of spatial abilities to student achievement across a broad range of domains and disciplines. Nets are one way to connect three-dimensional shapes and their two-dimensional representations and are a common focus of geometry curricula. Thirty-four students at year 6 (upper primary school) were interviewed on two occasions about their anticipation of whether or not given nets for the cube- and square-based pyramid would fold to form the target solid. Vergnaud's ( Journal of Mathematical Behavior, 17(2), 167-181, 1998, Human Development, 52, 83-94, 2009) four characteristics of schemes were used as a theoretical lens to analyse the data. Successful schemes depended on the interaction of operational invariants, such as strategic choice of the base, rules for action, particularly rotation of shapes, and anticipations of composites of polygons in the net forming arrangements of faces in the solid. Inferences were rare. These data suggest that students need teacher support to make inferences, in order to create transferable schemes.

  11. Anticipation of the landing shock phenomenon in flight simulation

    Mcfarland, Richard E.

    1987-01-01

    An aircraft landing may be described as a controlled crash because a runway surface is intercepted. In a simulation model the transition from aerodynamic flight to weight on wheels involves a single computational cycle during which stiff differential equations are activated; with a significant probability these initial conditions are unrealistic. This occurs because of the finite cycle time, during which large restorative forces will accompany unrealistic initial oleo compressions. This problem was recognized a few years ago at Ames Research Center during simulation studies of a supersonic transport. The mathematical model of this vehicle severely taxed computational resources, and required a large cycle time. The ground strike problem was solved by a described technique called anticipation equations. This extensively used technique has not been previously reported. The technique of anticipating a significant event is a useful tool in the general field of discrete flight simulation. For the differential equations representing a landing gear model stiffness, rate of interception and cycle time may combine to produce an unrealistic simulation of the continuum.

  12. Deterministic and Probabilistic Analysis against Anticipated Transient Without Scram

    Choi, Sun Mi; Kim, Ji Hwan; Seok, Ho

    2016-01-01

    An Anticipated Transient Without Scram (ATWS) is an Anticipated Operational Occurrences (AOOs) accompanied by a failure of the reactor trip when required. By a suitable combination of inherent characteristics and diverse systems, the reactor design needs to reduce the probability of the ATWS and to limit any Core Damage and prevent loss of integrity of the reactor coolant pressure boundary if it happens. This study focuses on the deterministic analysis for the ATWS events with respect to Reactor Coolant System (RCS) over-pressure and fuel integrity for the EU-APR. Additionally, this report presents the Probabilistic Safety Assessment (PSA) reflecting those diverse systems. The analysis performed for the ATWS event indicates that the NSSS could be reached to controlled and safe state due to the addition of boron into the core via the EBS pump flow upon the EBAS by DPS. Decay heat is removed through MSADVs and the auxiliary feedwater. During the ATWS event, RCS pressure boundary is maintained by the operation of primary and secondary safety valves. Consequently, the acceptance criteria were satisfied by installing DPS and EBS in addition to the inherent safety characteristics

  13. Adaptability of expert visual anticipation in baseball batting.

    Müller, Sean; Fadde, Peter J; Harbaugh, Allen G

    2017-09-01

    By manipulating stimulus variation in terms of opponent pitcher actions, this study investigated the capability of expert (n = 30) and near-expert (n = 95) professional baseball batters to adapt anticipation skill when using the video simulation temporal occlusion paradigm. Participants watched in-game footage of two pitchers, one after the other, that was temporally occluded at ball release and various points during ball flight. They were required to make a written prediction of pitch types and locations. Per cent accuracy was calculated for pitch type, for pitch location, and for type and location combined. Results indicated that experts and near-experts could adapt their anticipation to predict above guessing level across both pitchers, but adaptation to the left-handed pitcher was poorer than the right-handed pitcher. Small-to-moderate effect sizes were found in terms of superior adaptation by experts over near-experts at the ball release and early ball flight occlusion conditions. The findings of this study extend theoretical and applied knowledge of expertise in striking sports. Practical application of the instruments and findings are discussed in terms of applied researchers, practitioners and high-performance staff in professional sporting organisations.

  14. Deterministic and Probabilistic Analysis against Anticipated Transient Without Scram

    Choi, Sun Mi; Kim, Ji Hwan [KHNP Central Research Institute, Daejeon (Korea, Republic of); Seok, Ho [KEPCO Engineering and Construction, Daejeon (Korea, Republic of)

    2016-10-15

    An Anticipated Transient Without Scram (ATWS) is an Anticipated Operational Occurrences (AOOs) accompanied by a failure of the reactor trip when required. By a suitable combination of inherent characteristics and diverse systems, the reactor design needs to reduce the probability of the ATWS and to limit any Core Damage and prevent loss of integrity of the reactor coolant pressure boundary if it happens. This study focuses on the deterministic analysis for the ATWS events with respect to Reactor Coolant System (RCS) over-pressure and fuel integrity for the EU-APR. Additionally, this report presents the Probabilistic Safety Assessment (PSA) reflecting those diverse systems. The analysis performed for the ATWS event indicates that the NSSS could be reached to controlled and safe state due to the addition of boron into the core via the EBS pump flow upon the EBAS by DPS. Decay heat is removed through MSADVs and the auxiliary feedwater. During the ATWS event, RCS pressure boundary is maintained by the operation of primary and secondary safety valves. Consequently, the acceptance criteria were satisfied by installing DPS and EBS in addition to the inherent safety characteristics.

  15. Coincidence-anticipation timing requirements are different in racket sports.

    Akpinar, Selçuk; Devrilmez, Erhan; Kirazci, Sadettin

    2012-10-01

    The aim of this study was to compare the coincidence-anticipation timing accuracy of athletes of different racket sports with various stimulus velocity requirements. Ninety players (15 girls, 15 boys for each sport) from tennis (M age = 12.4 yr., SD = 1.4), badminton (M age = 12.5 yr., SD = 1.4), and table tennis (M age = 12.4 yr., SD = 1.2) participated in this study. Three different stimulus velocities, low, moderate, and high, were used to simulate the velocity requirements of these racket sports. Tennis players had higher accuracy when they performed under the low stimulus velocity compared to badminton and table tennis players. Badminton players performed better under the moderate speed comparing to tennis and table tennis players. Table tennis players had better performance than tennis and badminton players under the high stimulus velocity. Therefore, visual and motor systems of players from different racket sports may adapt to a stimulus velocity in coincidence-anticipation timing, which is specific to each type of racket sports.

  16. The Boxing Day Tsunami: Could the Disaster have been Anticipated?

    Cummins, P. R.; Burbdige, D.

    2005-05-01

    The occurrence of the 26 December, 2004 Sumatra-Andaman earthquake and the accompanying "Boxing Day" Tsunami, which killed over 280,00, has been described as one of the most lethal natural disasters in human history. Many lives could have been saved had a tsunami warning system, similar to that which exists for the Pacific Ocean, been in operation for the Indian Ocean. The former exists because great subduction zone earthquakes have generated destructive, Pacific-wide tsunami in the Pacific Ocean with some frequency. Prior to 26 December, 2004, all of the world's earthquakes with magnitude > 9 were widely thought to have occurred in the Pacific Ocean, where they caused destructive tsunami. Could the occurrence of similar earthquakes and tsunami in the Indian Ocean been predicted prior to the 2004 Box Day Tragedy? This presentation will argue that the answer is "Yes". Almost without exception (the exception being the 1952 Kamchatka earthquake) the massive subduction zone earthquakes and tsunami of the Pacific Ocean have been associated with the subduction of relatively young ocean lithosphere (Boxing day event, the effects in the Bay of Bengal would not have been as severe. Thus, it seems to this author that the Boxing Day event could and should have been anticipated. This presentation will further consider why it was not, and what steps can be taken to anticipate and mitigate the effects of future events that may occur in the Indian Ocean and elsewhere.

  17. Nuclear Electric Visitor Centres - Innovation and inspiration

    Fenton, Bob

    1998-01-01

    Full text: This eight minute video demonstrates the approach taken by Nuclear Electric to exhibitions that are open to the public. The information is given both visually - with excerpts from some of the attractions on display at the centres - and in comments from interviews with visitors, the centre guides and the man responsible for many of the exhibits featured in the video. on one side are the schoolchildren who are visiting the exhibition and are seen both playing and learning as they press buttons, watch videos, 'meet' Michael Faraday, and learn about radiation - its disposal and its safe transportation. The headmaster of the school is interviewed and explains that the exhibition is helping his children understand the importance of electricity to their world. on the other side is Jackie Lucas, the visitor centre manager, explaining what the public make of the exhibition. We see her staff greeting the children and helping them to understand the show. The designer of the exhibition, Len Upton explains how you go about making an exhibition such as this both informative and fun. Also interviewed is the man behind many of the exhibitions featured at Nuclear Electric's visitor centres up and down the country, Nicholas Mullane. He explains the purpose of the exhibition and what messages it imparts. The video is presented in split-screen or composite format, whereby the interviewee and children are often presented together. Excerpts from the various videos on display are presented as both how they are seen from the floor, as well as the full screen effect of the various programmes. The video gives much of the feeling of fun to be gained at the exhibition, as well as showing the educational benefits to be gained from a couple of hours at one of Nuclear Electric's visitor centres. Copies of the video can be obtained from Bob Fenton at Nuclear Electric. (Fax: ++44 1 452 652 443). (author)

  18. Speciality preferences in Dutch medical students influenced by their anticipation on family responsibilities.

    Alers, Margret; Pepping, Tess; Bor, Hans; Verdonk, Petra; Hamberg, Katarina; Lagro-Janssen, Antoine

    2014-12-01

    Physician gender is associated with differences in the male-to-female ratio between specialities and with preferred working hours. We explored how graduating students' sex or full-time or part-time preference influences their speciality choice, taking work-life issues into account. Graduating medical students at Radboud University Medical Centre, the Netherlands participated in a survey (2008-2012) on career considerations. Logistic regression tested the influence of sex or working hour preference on speciality choice and whether work-life issues mediate. Of the responding students (N = 1,050, response rate 83, 73.3 % women), men preferred full-time work, whereas women equally opted for part time. More men chose surgery, more women family medicine. A full-time preference was associated with a preference for surgery, internal medicine and neurology, a part-time preference with psychiatry and family medicine. Both male and female students anticipated that foremost the career of women will be negatively influenced by family life. A full-time preference was associated with an expectation of equality in career opportunities or with a less ambitious partner whose career would affect family life. This increased the likelihood of a choice for surgery and reduced the preference for family medicine among female students. Gender specifically plays an important role in female graduates' speciality choice making, through considerations on career prospects and family responsibilities.

  19. Mochovce waste treatment centre

    Sedliak, D.; Endrody, J.

    2000-01-01

    The first unit of the Mochovce NPP (WWER 440 MW) was put in a test operation in October 1998. The second unit with the same power output was put in the test operation in March 2000. The Nuclear Regulatory Authority of the Slovak Republic in its Decision No. 318/98 of 28 October 1998, by which an agreement with the operation of the Unit 1 of the Mochovce. Nuclear Power Plant was issued, requires to start the construction of the Liquid Radioactive Waste Treatment Centre until January 2004. The subject of this presentation is a system description of the Liquid Radioactive Waste (LRW) management in the Mochovce NPP. The initial part is dedicated to a short description of the radioactive waste management legislation requirements. Then the presentation continues with an information about the LRW production in the Mochovce NPP, LRW sources, chemical and radiochemical attributes, description of storage. The presentation also provides real values of its production in a comparison with the design data. The LRW production minimization principles are also mentioned there. Another part deals with the basic requirements for the technology proposal of the liquid RW treatment, especially concerning the acceptance criteria at the Republic RW Repository Mochovce. The final part is devoted to a short description of the investment procedure principles - design preparation levels and a proposed construction schedule of the centre. (authors)

  20. The influence of anticipated pride and guilt on pro-environmental decision making.

    Claudia R Schneider

    Full Text Available The present research explores the relationship between anticipated emotions and pro-environmental decision making comparing two differently valenced emotions: anticipated pride and guilt. In an experimental design, we examined the causal effects of anticipated pride versus guilt on pro-environmental decision making and behavioral intentions by making anticipated emotions (i.e. pride and guilt salient just prior to asking participants to make a series of environmental decisions. We find evidence that anticipating one's positive future emotional state from green action just prior to making an environmental decision leads to higher pro-environmental behavioral intentions compared to anticipating one's negative emotional state from inaction. This finding suggests a rethinking in the domain of environmental and climate change messaging, which has traditionally favored inducing negative emotions such as guilt to promote pro-environmental action. Furthermore, exploratory results comparing anticipated pride and guilt inductions to baseline behavior point toward a reactance eliciting effect of anticipated guilt.

  1. The influence of anticipated pride and guilt on pro-environmental decision making.

    Schneider, Claudia R; Zaval, Lisa; Weber, Elke U; Markowitz, Ezra M

    2017-01-01

    The present research explores the relationship between anticipated emotions and pro-environmental decision making comparing two differently valenced emotions: anticipated pride and guilt. In an experimental design, we examined the causal effects of anticipated pride versus guilt on pro-environmental decision making and behavioral intentions by making anticipated emotions (i.e. pride and guilt) salient just prior to asking participants to make a series of environmental decisions. We find evidence that anticipating one's positive future emotional state from green action just prior to making an environmental decision leads to higher pro-environmental behavioral intentions compared to anticipating one's negative emotional state from inaction. This finding suggests a rethinking in the domain of environmental and climate change messaging, which has traditionally favored inducing negative emotions such as guilt to promote pro-environmental action. Furthermore, exploratory results comparing anticipated pride and guilt inductions to baseline behavior point toward a reactance eliciting effect of anticipated guilt.

  2. Experienced and anticipated discrimination reported by individuals in treatment for substance use disorders within the Netherlands

    van Boekel, L.C.; Brouwers, E.P.M.; van Weeghel, J.; Garretsen, H.F.L.

    2016-01-01

    Experiences and expectations of discrimination (anticipated discrimination) may delay treatment seeking among people with substance use disorders. In addition, experienced and anticipated discrimination can be a barrier to successful recovery and rehabilitation. The aim of this study was to study

  3. The impact of group composition and attitudes towards diversity on anticipated outcomes of diversity in groups

    van Oudenhoven-van der Zee, Karen; Paulus, Paul; Vos, Menno; Parthasarathy, Niveditha

    In two studies, students evaluated group pictures of workgroups of varying ethnic and gender composition with respect to anticipated affective and productive outcomes. The impact of level of diversity, faultlines and individual differences in diversity attitudes on anticipated outcomes were

  4. Anticipative Criminal Investigation : Theory and Counterterrorism Practice in the Netherlands and the United States

    Hirsch Ballin, M.F.H.

    2012-01-01

    The book assesses the adoption of counterterrorism measures in the Netherlands and the United States, which facilitate criminal investigations with a preventive focus (anticipative criminal investigations), from the perspective of rule of law principles. Anticipative criminal investigation has

  5. The influence of anticipated pride and guilt on pro-environmental decision making

    Schneider, Claudia R.; Zaval, Lisa; Weber, Elke U.; Markowitz, Ezra M.

    2017-01-01

    The present research explores the relationship between anticipated emotions and pro-environmental decision making comparing two differently valenced emotions: anticipated pride and guilt. In an experimental design, we examined the causal effects of anticipated pride versus guilt on pro-environmental decision making and behavioral intentions by making anticipated emotions (i.e. pride and guilt) salient just prior to asking participants to make a series of environmental decisions. We find evide...

  6. NNC's engineering development centre at Risley

    Garnsey, R.

    1994-01-01

    NNC's Engineering Development Centre (EDC) provides specialist engineering, manufacturing and development support to customers. EDC is located at Risley, near Warrington, but its operation are closely integrated into the Company's overall business activities based at its headquarters in Knutsford, Cheshire, fifteen miles away. EDC's facilities and expertise were originally developed to support the UK's nuclear power station construction programme. However, EDC professionals have since applied their specialist expertise to the benefit of new customers in line with the Company's diversification and a large and growing proportion of work is now in support of the defence and process industries. (author)

  7. Ecodriving acceptance : an experimental study on anticipation behavior of truck drivers

    Thijssen, R.J.T.G.; Hofman, T.; Ham, J.R.C.

    2014-01-01

    In this paper, it is researched to what extend truck drivers are willing to improve their anticipation behavior. For the purpose of this research, anticipation behavior is characterized by anticipation distance: the distance to a stopping point (e.g. roundabout), at which the accelerator pedal is

  8. Improving the Impact of Extension through the Use of Anticipation Guides

    Smith, Rebecca C.; Lemley, Stephanie M.

    2017-01-01

    In this article, we present the anticipation guide as a tool for preparing Extension audiences to learn the main points of Extension materials. Anticipation guides improve learner comprehension by appealing to an individual's natural curiosity and helping the individual focus on key ideas. Anticipation guides can be used with all types of…

  9. Conserving critical sites for biodiversity provides disproportionate benefits to people

    Larsen, Frank Wugt; Turner, Will R.; Brooks, Thomas M.

    2012-01-01

    Protecting natural habitats in priority areas is essential to halt the loss of biodiversity. Yet whether these benefits for biodiversity also yield benefits for human well-being remains controversial. Here we assess the potential human well-being benefits of safeguarding a global network of sites......) benefits to maintenance of human cultural diversity - significantly exceeding those anticipated from randomly selected sites within the same countries and ecoregions. Results suggest that safeguarding sites important for biodiversity conservation provides substantial benefits to human well-being....

  10. An anticipative escape system for vehicles in water crashes

    Shen, Chuanliang; Wang, Jiawei; Yin, Qi; Zhu, Yantao; Yang, Jiawei; Liao, Mengdi; Yang, Liming

    2017-07-01

    In this article, it designs an escape system for vehicles in water crashes. The structure mainly contains sensors, control organs and actuating mechanism for both doors and windows. Sensors judge whether the vehicle falls into water or is in the falling process. The actuating mechanism accepts the signal delivered by the control organs, then open the electronic central lock on doors and meanwhile lower the window. The water escape system is able to anticipate drowning situations for vehicles and controls both doors and windows in such an emergency. Under the premise of doors staying in an undamaged state, it is for sure that people in the vehicle can open the door while drowning in the water and safely escape.

  11. Systems and models with anticipation in physics and its applications

    Makarenko, A

    2012-01-01

    Investigations of recent physics processes and real applications of models require the new more and more improved models which should involved new properties. One of such properties is anticipation (that is taking into accounting some advanced effects).It is considered the special kind of advanced systems – namely a strong anticipatory systems introduced by D. Dubois. Some definitions, examples and peculiarities of solutions are described. The main feature is presumable multivaluedness of the solutions. Presumable physical examples of such systems are proposed: self-organization problems; dynamical chaos; synchronization; advanced potentials; structures in micro-, meso- and macro- levels; cellular automata; computing; neural network theory. Also some applications for modeling social, economical, technical and natural systems are described.

  12. Anticipated transients without scram for light water reactors

    1978-12-01

    In the first two volumes of this report, Anticipated Transients without Scram for Light Water Reactors NUREG-0460, dated April 1978, the NRC staff reviewed the information on this subject that had been developed in the past and evaluated the susceptibility of current nuclear plants to ATWS events using fault tree/event tree analysis techniques. Based on that evaluation, the staff concluded that some corrective measures were required to reduce the risk of severe consequences arising from possible ATWS events. Since the issuance of NUREG-0460, new safety and cost information has become available on ATWS. Also, new insights have been developed on the general subject of quantitative risk assessment. The purpose of this supplement to NUREG-0460 is to summarize the important additions to the information base and to propose a course of action from among a variety of alternatives for resolving the ATWS concern

  13. The rise of sea level. To understand and to anticipate

    2013-03-01

    By proposing and briefly commenting graphs and drawings, this publication propose brief presentations of the main issues related to sea level rise: global warming and climate disturbance, description of the phenomenon of sea level rise (difference between sea ice and ground ice, melting of glaciers), increase of sea level rise during the twentieth century, territories at risk (examples of Greenland, Tuvalu, Shanghai), acceleration of ice melting during the twenty first century with many coastal areas at risk, already noticed and possible future impacts in France (glaciers runoff, threatened coasts, example of the Xynthia tempest), how to be united and to anticipate (a threat for millions of people, adaptation to sea level rise, limitation of global warming to limit sea level rise)

  14. Vision for a Global Registry of Anticipated Public Health Studies

    Choi, Bernard C.K.; Frank, John; Mindell, Jennifer S.; Orlova, Anna; Lin, Vivian; Vaillancourt, Alain D.M.G.; Puska, Pekka; Pang, Tikki; Skinner, Harvey A.; Marsh, Marsha; Mokdad, Ali H.; Yu, Shun-Zhang; Lindner, M. Cristina; Sherman, Gregory; Barreto, Sandhi M.; Green, Lawrence W.; Svenson, Lawrence W.; Sainsbury, Peter; Yan, Yongping; Zhang, Zuo-Feng; Zevallos, Juan C.; Ho, Suzanne C.; de Salazar, Ligia M.

    2007-01-01

    In public health, the generation, management, and transfer of knowledge all need major improvement. Problems in generating knowledge include an imbalance in research funding, publication bias, unnecessary studies, adherence to fashion, and undue interest in novel and immediate issues. Impaired generation of knowledge, combined with a dated and inadequate process for managing knowledge and an inefficient system for transferring knowledge, mean a distorted body of evidence available for decisionmaking in public health. This article hopes to stimulate discussion by proposing a Global Registry of Anticipated Public Health Studies. This prospective, comprehensive system for tracking research in public health could help enhance collaboration and improve efficiency. Practical problems must be discussed before such a vision can be further developed. PMID:17413073

  15. Realizing the financial benefits of capitation arbitrage.

    Sussman, A J; Fairchild, D G; Colling, M C; Brennan, T A

    1999-11-01

    By anticipating the arbitrage potential of cash flow under budgeted capitation, healthcare organizations can make the best use of cash flow as a revenue-generating resource. Factors that determine the magnitude of the benefits for providers and insurers include settlement interval, withhold amount, which party controls the withhold, and incurred-but-not-reported expenses. In choosing how to structure these factors in their contract negotiations, providers and insurers should carefully assess whether capitation surpluses or deficits can be expected from the provider. In both instances, the recipient and magnitude of capitation arbitrage benefits are dictated largely by the performance of the provider.

  16. Strong anticipation: Multifractal cascade dynamics modulate scaling in synchronization behaviors

    Stephen, Damian G.; Dixon, James A.

    2011-01-01

    Research highlights: → We investigated anticipatory behaviors in response to chaotic metronomes. → We assessed multifractal structure in tap intervals and onset intervals. → Strength of multifractality in tap intervals appears to match that in onset intervals. - Abstract: Previous research on anticipatory behaviors has found that the fractal scaling of human behavior may attune to the fractal scaling of an unpredictable signal [Stephen DG, Stepp N, Dixon JA, Turvey MT. Strong anticipation: Sensitivity to long-range correlations in synchronization behavior. Physica A 2008;387:5271-8]. We propose to explain this attunement as a case of multifractal cascade dynamics [Schertzer D, Lovejoy S. Generalised scale invariance in turbulent phenomena. Physico-Chem Hydrodyn J 1985;6:623-5] in which perceptual-motor fluctuations are coordinated across multiple time scales. This account will serve to sharpen the contrast between strong and weak anticipation: whereas the former entails a sensitivity to the intermittent temporal structure of an unpredictable signal, the latter simply predicts sensitivity to an aggregate description of an unpredictable signal irrespective of actual sequence. We pursue this distinction through a reanalysis of Stephen et al.'s data by examining the relationship between the widths of singularity spectra for intertap interval time series and for each corresponding interonset interval time series. We find that the attunement of fractal scaling reported by Stephen et al. was not the trivial result of sensitivity to temporal structure in aggregate but reflected a subtle sensitivity to the coordination across multiple time scales of fluctuation in the unpredictable signal.

  17. Call Centre- Computer Telephone Integration

    Dražen Kovačević

    2012-10-01

    Full Text Available Call centre largely came into being as a result of consumerneeds converging with enabling technology- and by the companiesrecognising the revenue opportunities generated by meetingthose needs thereby increasing customer satisfaction. Regardlessof the specific application or activity of a Call centre, customersatisfaction with the interaction is critical to the revenuegenerated or protected by the Call centre. Physical(v, Call centreset up is a place that includes computer, telephone and supervisorstation. Call centre can be available 24 hours a day - whenthe customer wants to make a purchase, needs information, orsimply wishes to register a complaint.

  18. Paying with money or effort: Pricing when customers anticipate hassle

    Lambrecht, Anja; Tucker, Catherine Elizabeth

    2012-01-01

    For many services, customers subscribe to long-term contracts. Standard economic theory suggests that customers evaluate a contract on the basis of its overall net benefits. the authors suggest that rather than evaluating multiperiod service contracts at the contract level, customers use period-level bracketing. customers evaluate the distinct per-period loss or gain they incur from choosing this contract. this has important consequences when benefits vary over the course of the contract—for ...

  19. The Centres for Environment-friendly Energy Research (FME)

    NONE

    2011-07-01

    public administration and various types of organisations. Uniting the strongest players within a specific area under the aegis of a single centre gives each centre a very high level of overall expertise. The FME centres do not comprise an institution in a single geographic location but rather represent a grouping of entities with unique competencies in relevant areas. Adequate funding is critical to the centres success and further development. The centres each receive NOK 8-20 million annually for a five-year period, with the potential for a three-year extension. The Research Council will evaluate each centre individually and determine whether to grant further funding beyond the initial five-year period. The FME centres are expected to keep on boosting Norwegian energy-related expertise well into the future, with the benefits of their activities extending far beyond the actual lifecycle of the centres themselves. Individually and together, the FME centres will help to provide a secure energy future for Norway and the world at large.(Author)

  20. Anticipating the Future, Influencing the Present: Assessing the Societal Implications of Emerging Technologies

    Michelson, Evan S.

    A growing challenge for the American policymaking system is to respond effectively to a wide range of interconnected, complex, long-term science and technology issues. Simultaneously, current approaches and institutions of governance are ill suited to address these multidimensional challenges. As the next generation of innovations in science and technology is arriving at an accelerating rate, the governance system is lagging behind. This realization leads to a vital overarching consideration that steers this study: What approaches are well suited to anticipate the longer-term societal implications of emerging technologies in the 21st Century? This study identifies and examines strategies for anticipating the longer-term societal implications of emerging technologies by way of a qualitative case study. It explores one area of technology (nanotechnology), in one particular governance system (the United States), and with a focus on one high profile non-governmental organization (NGO) involved in addressing a range of nanotechnology's societal and policy implications: the Project on Emerging Nanotechnologies (PEN). Based at the Woodrow Wilson International Center for Scholars, PEN's goal was to ensure "that as nanotechnologies advance, possible risks are minimized, public and consumer engagement remains strong, and the potential benefits of these new technologies are realized." The conceptual framework of anticipatory governance guides the research, which offers a real-world example about how anticipatory governance applies in the nongovernmental sector and shows how this idea links to broader theoretical debates about the policymaking process. The study's main conclusion is that PEN utilized a set of interconnected strategies related to advancing foresight, operating in a boundary-spanning role, and promoting communications and public engagement in its attempt to influence, anticipate, and shape the societal implications of emerging technologies. The findings are

  1. Consensus statement on the anticipation and prevention of acute postoperative pain: multidisciplinary RADAR approach.

    Vickers, A; Bali, S; Baxter, A; Bruce, G; England, J; Heafield, R; Langford, R; Makin, R; Power, I; Trim, J

    2009-10-01

    There has been considerable investment in efforts to improve postoperative pain management, including the introduction of acute pain teams. There have also been a number of guidelines published on postoperative pain management and there is widespread agreement on how pain should be practically managed. Despite these advances, there is no apparent improvement in the number of patients experiencing moderately severe or extreme pain after surgery. This highlights significant scope for improvement in acute postoperative pain management. In January 2009, a multidisciplinary UK expert panel met to define and agree a practical framework to encourage implementation of the numerous guidelines and fundamentals of pain management at a local level. The panel recognised that to do this, there was a need to organise the information and guidelines into a simplified, accessible and easy-to-implement system based on their practical clinical experience. Given the volume of literature in this area, the Chair recommended that key international guidelines from professional bodies should be distributed and then reviewed during the meeting to form the basis of the framework. Consensus was reached by unanimous agreement of all ten participants. This report provides a framework for the key themes, including consensus recommendations based upon practical experience agreed during the meeting, with the aim of consolidating the key guidelines to provide a fundamental framework which is simple to teach and implement in all areas. Key priorities that emerged were: Responsibility, Anticipation, Discussion, Assessment and Response. This formed the basis of RADAR, a novel framework to help pain specialists educate the wider care team on understanding and prioritising the management of acute pain. Acute postoperative pain can be more effectively managed if it is prioritised and anticipated by a well-informed care team who are educated with regard to appropriate analgesic options and understand what

  2. The Optimal Time for Claiming Social Security Benefits: A Methodological Note

    Joseph Friedman

    2014-01-01

    The optimal age for initiating Social Security benefits and the initiation versus postponement of benefits decision are the subjects of a number of recent papers. It is generally agreed that an initiation versus postponement of benefits decision may have significant consequences, but there is less agreement about how to model the problem or measure its financial implications. By law benefits are paid only to live beneficiaries. Thus, the anticipated future benefits should be weighted by the r...

  3. INTRODUCTION: Anticipated changes in the global atmospheric water cycle

    Allan, Richard P.; Liepert, Beate G.

    2010-06-01

    The atmospheric branch of the water cycle, although containing just a tiny fraction of the Earth's total water reserves, presents a crucial interface between the physical climate (such as large-scale rainfall patterns) and the ecosystems upon which human societies ultimately depend. Because of the central importance of water in the Earth system, the question of how the water cycle is changing, and how it may alter in future as a result of anthropogenic changes, present one of the greatest challenges of this century. The recent Intergovernmental Panel on Climate Change report on Climate Change and Water (Bates et al 2008) highlighted the increasingly strong evidence of change in the global water cycle and associated environmental consequences. It is of critical importance to climate prediction and adaptation strategies that key processes in the atmospheric water cycle are precisely understood and determined, from evaporation at the surface of the ocean, transport by the atmosphere, condensation as cloud and eventual precipitation, and run-off through rivers following interaction with the land surface, sub-surface, ice, snow and vegetation. The purpose of this special focus issue of Environmental Research Letters on anticipated changes in the global atmospheric water cycle is to consolidate the recent substantial advances in understanding past, present and future changes in the global water cycle through evidence built upon theoretical understanding, backed up by observations and borne out by climate model simulations. Thermodynamic rises in water vapour provide a central constraint, as discussed in a guest editorial by Bengtsson (2010). Theoretical implications of the Clausius-Clapeyron equation are presented by O'Gorman and Muller (2010) and with reference to a simple model (Sherwood 2010) while observed humidity changes confirm these anticipated responses at the land and ocean surface (Willett et al 2008). Rises in low-level moisture are thought to fuel an

  4. Council celebrates CERN Control Centre

    2006-01-01

    With the unveiling of its new sign, the CERN Control Centre was officially inaugurated on Thursday 16 March. To celebrate its startup, CERN Council members visited the sleek centre, a futuristic-looking room filled with a multitude of monitoring screens.

  5. The Aube centre. 1997 statement

    1998-09-01

    Since January 1992 the Aube centre ensures the storage of 90% of the short life radioactive wastes produced in France. This educational booklet describes the organization of the activities in the centre from the storage of wastes to the radioactivity surveillance of the environment (air, surface and ground waters, river sediments, plants and milk). (J.S.)

  6. Overcoming the Educational Time Warp: Anticipating a Different Future

    Garry Jacobs

    2015-10-01

    Full Text Available Education abridges the time required for individual and social progress by preserving and propagating the essence of human experience. It delivers to youth the accumulated knowledge of countless past generations in an organized and abridged form, so that future generations can start off with all the capacities acquired by their predecessors. However, today education confronts a serious dilemma. We are living in an educational time warp. There is a growing gap between contemporary human experience and what is taught in our educational system and that gap is widening rapidly with each passing year. Today humanity confronts challenges of unprecedented scope, magnitude and intensity. The incremental development of educational content and pedagogy in recent decades has not kept with the ever-accelerating pace of technological and social evolution. Education is also subject to a generational time warp resulting from the fact that many of today’s teachers were educated decades ago during very different times and based on different values and perspectives. The challenge of preparing youth for the future is exasperated by the fact that the future for which we are educating youth does not yet exist and to a large extent is unknown or unknowable. The resulting gap between the content of education and societal needs inhibits our capacity to anticipate and effectively respond to social problems. All these factors argue for a major reorientation of educational content and pedagogy from transmission of acquired knowledge based on past experience to development of the knowledge, skills and capacities of personality needed in a future we cannot clearly envision. We may not be able to anticipate the precise nature of the future, but we can provide an education based on the understanding that it will be very different from the present. In terms of content, the emphasis needs to shift from facts regarding the actual state of affairs in the past, present and

  7. Anticipated SWOT Observations of Human Impacts on the Water Cycle

    Clark, E.; Andreadis, K.; Moller, D.; Lettenmaier, D. P.

    2012-12-01

    The impoundment of water behind dams alters the timing and magnitude of the discharge of rivers to the ocean, and hence sea level, as well as evaporation from the global land areas, and, through irrigation, the storage of water on land in the soil column. The impact of these effects on the global hydrologic cycle globally is difficult to estimate given currently available (and shared) observations of temporally varying reservoir storage. The upcoming joint U.S.-France Surface Water and Ocean Topography (SWOT) mission* will measure terrestrial surface water storage dynamics with unprecedented global coverage for managed reservoirs, as well as natural lakes and rivers. Previous studies have investigated SWOT's potential ability to measure storage change for some lakes; however, because reservoirs are typically located in flooded river valleys, they tend to be more elongate than the high latitude lakes that have been studied, and have more complex shorelines (and hence a longer land-water boundary). Furthermore, for reservoirs in mountainous regions, SWOT observations will be prone to topographic layover effects. Finally, the temporal variability of water levels in reservoirs is determined by management goals (i.e., hydropower, flood control, irrigation, supply, recreation), rather than climate, as in the case of natural lakes. We report an investigation of the potential accuracy of SWOT observations of storage change over selected managed reservoirs in the United States. First, we developed a time series of water height maps over each reservoir by combining available bathymetry data with observations of reservoir storage. We then simulated realistic SWOT observations of water level over these water bodies, given the planned SWOT orbital parameters, anticipated noise, and topographic layover errors. We also simulated a realistic tropospheric delay, modeled from daily MERRA reanalysis data. From these synthetic observations, we estimate the number of overpasses needed

  8. RTEMS CENTRE- RTEMS Improvement

    Silva, Helder; Constantino, Alexandre; Freitas, Daniel; Coutinho, Manuel; Faustino, Sergio; Sousa, Jose; Dias, Luis; Zulianello, Marco

    2010-08-01

    During the last two years, EDISOFT's RTEMS CENTRE team [1], jointly with the European Space Agency and with the support of the worldwide RTEMS community [2], have been developing an activity to facilitate the qualification of the real-time operating system RTEMS (Real-Time Operating System for Multiprocessor Systems). This paper intends to give a high level visibility of the progress and the results obtained in the RTEMS Improvement [3] activity. The primary objective [4] of the project is to improve the RTEMS product, its documentation and to facilitate the qualification of RTEMS for future space missions, taking into consideration the specific operational requirements. The sections below provide a brief overview of the RTEMS operating system and the activities performed in the RTEMS Improvement project, which includes the selection of API managers to be qualified, the tailoring process, the requirements analysis, the reverse engineering and design of the RTEMS, the quality assurance process, the ISVV activities, the test campaign, the results obtained, the criticality analysis and the facilitation of qualification process.

  9. Thailand's nuclear research centre

    Yamkate, P.

    2001-01-01

    The Office of Atomic Energy for Peace, Thailand, is charged with three main tasks, namely, Nuclear Energy development Plan, Utilization of Nuclear Based technology Plan and Science and Technology Plan. Its activities are centred around the research reactor TRR-1/M1. The main areas of contribution include improvement in agricultural production, nuclear medicine and nuclear oncology, health care and nutrition, increasing industrial productivity and efficiency and, development of cadre competent in nuclear science and technology. The office also has the responsibility of ensuring nuclear safety, radiation safety and nuclear waste management. The office has started a new project in 1997 under which a 10 MWt research reactor, an isotope production facility and a waste processing and storage facility would be set up by General Atomic of USA. OAEP has a strong linkage with the IAEA and has been an active participant in RCA programmes. In the future OAEP will enhance its present capabilities in the use of radioisotopes and radiation and look into the possibility of using nuclear energy as an alternative energy resource. (author)

  10. The Adult Education Centre

    Olga Drofenik

    1997-01-01

    Full Text Available The Adult Education Centre has drafted the professional foundations for the Master Plan for Adult Education which, according to the provisions stipulated in the Adult Education Act, will be adopted by the Parliament. The Master Plan specifies the goals, priority target groups, priority areas and a draft financial projection. The professional foundations include the ratings of adult education in studies about adult education trends in Slovenia and abroad. The paper presents research results relevant to the Master Plan and documents issued by international organizations, including research into the Decisive Global Factors of EC Development after 1992, the Report of Ministers of the OECD, and the Economic Development Strategy of Slovenia . All the above-mentioned documents emphasize the importance of life­long learning in achieving a more fulfilling personal life, faster economic growth and maintenance of social ties. In principle, the same views are shared in Slovenia. However, in practice the "multi-dimensional" nature of adult education often gives way to "education for production". This is why we especially stress the importance of adult education in the social and cultural context.

  11. Detecting, anticipating, and predicting critical transitions in spatially extended systems.

    Kwasniok, Frank

    2018-03-01

    A data-driven linear framework for detecting, anticipating, and predicting incipient bifurcations in spatially extended systems based on principal oscillation pattern (POP) analysis is discussed. The dynamics are assumed to be governed by a system of linear stochastic differential equations which is estimated from the data. The principal modes of the system together with corresponding decay or growth rates and oscillation frequencies are extracted as the eigenvectors and eigenvalues of the system matrix. The method can be applied to stationary datasets to identify the least stable modes and assess the proximity to instability; it can also be applied to nonstationary datasets using a sliding window approach to track the changing eigenvalues and eigenvectors of the system. As a further step, a genuinely nonstationary POP analysis is introduced. Here, the system matrix of the linear stochastic model is time-dependent, allowing for extrapolation and prediction of instabilities beyond the learning data window. The methods are demonstrated and explored using the one-dimensional Swift-Hohenberg equation as an example, focusing on the dynamics of stochastic fluctuations around the homogeneous stable state prior to the first bifurcation. The POP-based techniques are able to extract and track the least stable eigenvalues and eigenvectors of the system; the nonstationary POP analysis successfully predicts the timing of the first instability and the unstable mode well beyond the learning data window.

  12. In Wrong Anticipation - Miscalibrated Beliefs between Germans, Israelis, and Palestinians.

    Sebastian J Goerg

    Full Text Available The reconcilability of actions and beliefs in inter-country relationships, either in business or politics, is of vital importance as incorrect beliefs on foreigners' behavior can have serious implications. We study a typical inter-country interaction by means of a controlled laboratory investment game experiment in Germany, Israel and Palestine involving 400 student participants in total. An investor has to take a risky decision in a foreign country that involves transferring money to an investee/allocator. We found a notable constellation of calibrated and un-calibrated beliefs. Within each country, transfer standards exist, which investees correctly anticipate within their country. However, across countries these standards differ. By attributing the standard of their own environment to the other countries investees are remarkably bad in predicting foreign investors' behavior. The tendency to ignore this potential difference can be a source of misinterpreting motives in cross-country interaction. Foreigners might perceive behavior as unfavorable or favorable differentiation, even though-unknown to them-investors actually treat fellow-country people and foreigners alike.

  13. Current and anticipated uses of thermal hydraulic codes in Korea

    Kim, Kyung-Doo; Chang, Won-Pyo [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1997-07-01

    In Korea, the current uses of thermal hydraulic codes are categorized into 3 areas. The first application is in designing both nuclear fuel and NSSS. The codes have usually been introduced based on the technology transfer programs agreed between KAERI and the foreign vendors. Another area is in the supporting of the plant operations and licensing by the utility. The third category is research purposes. In this area assessments and some applications to the safety issue resolutions are major activities using the best estimate thermal hydraulic codes such as RELAP5/MOD3 and CATHARE2. Recently KEPCO plans to couple thermal hydraulic codes with a neutronics code for the design of the evolutionary type reactor by 2004. KAERI also plans to develop its own best estimate thermal hydraulic code, however, application range is different from KEPCO developing code. Considering these activities, it is anticipated that use of the best estimate hydraulic analysis code developed in Korea may be possible in the area of safety evaluation within 10 years.

  14. Blunted cardiovascular reactivity in dysphoria during reward and punishment anticipation.

    Franzen, Jessica; Brinkmann, Kerstin

    2015-03-01

    Hyposensitivity to reward in depression and dysphoria has been found in behavioral and neuroimaging studies. For punishment responsiveness, some studies showed hyposensitivity to punishment while other studies demonstrated hypersensitivity. Only few studies have addressed the motivational question as to whether depressed individuals mobilize less effort in anticipation of a positive or a negative consequence. The present study aimed at investigating reward and punishment responsiveness in subclinical depression from an effort mobilization perspective. Working on a recognition memory task, one third of the participants could earn small amounts of money, one third could lose small amounts of money, and one third could neither earn nor lose money. Effort mobilization was operationalized as participants' cardiovascular reactivity during task performance. As expected, reactivity of cardiac pre-ejection period and heart rate was higher in both incentive conditions compared to the neutral condition for nondysphorics, while it was blunted across conditions for dysphorics. Moreover, the present study found that dysphorics show an altered behavioral response to punishment. These findings thus show that dysphorics present a reduced motivation to obtain a reward or to avoid a punishment in terms of reduced effort-related cardiac reactivity. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. Rare disease patients in China anticipate the sunlight of legislation.

    Gao, J J; Song, P P; Tang, W

    2013-06-01

    It is estimated that there are over ten million rare disease patients in China currently. Due to a lack of effective drugs and reimbursement regulations for medical expenses the diseases bring most patients enormous physical suffering and psychological despair. Past experience in other countries such as the United States, Japan, and the European Union have shown that legislation is the critical step to improve the miserable situation of rare disease patients. Laws and regulations for rare diseases in these countries prescribe a series of incentives for research and development of orphan drugs which turn out to obviously allow these drugs to flourish. Legislation has also established a drug reimbursement system to reduce the medical burden of the patients. These measures effectively protect the rights and interests of patients with rare diseases. In China, legislation for rare diseases has begun to attract the attention of authorities. It is anticipated that relevant laws and regulations will be established as early as possible to provide safeguards for rare disease patients in China.

  16. LWR fuel performance during anticipated transients with scram

    Martinson, Z.R.; McCardell, R.K.; MacDonanl, P.E.; Rowland, T.C.; Tokar, M.

    1983-01-01

    Operational transients occur occasionally in light water reactors when minor malfunctions of certain system components affect the reactor core. Potential effects of such malfunctions include a loss of the secondary heat sink, an increase in system pressure, and, in boiling water reactors, void collapse and a brief increase in reactor power. The most severe postulated Boiling Water Reactor (BWR) anticipated transient is characterized by a power peak of up to 495% rated power for about 1 second (according to a recent General Electric Co., generic analysis). The results of a series of fuel behaviour tests in the Power Burst Facility (PBF) at the Idaho National Engineering Laboratory are presented in this paper. Four progressively higher and broader power transients at a constant coolant flow rate were performed. The first transient simulated a BWR-5 turbine trip without steam bypass with fuel rods operating at BWR-6 core average rod powers. The second transient simulated a generator load rejection without steam bypass with fuel rods operating at above core average powers. The last two transients were performed at higher powers than safety analysis predicts to be possible in commercial reactors to be defined failure threshold margins. The test rods did not fail and were not damaged during any of the four transients. (author)

  17. Preparedness for emerging infectious diseases: pathways from anticipation to action.

    Brookes, V J; Hernández-Jover, M; Black, P F; Ward, M P

    2015-07-01

    Emerging and re-emerging infectious disease (EID) events can have devastating human, animal and environmental health impacts. The emergence of EIDs has been associated with interconnected economic, social and environmental changes. Understanding these changes is crucial for EID preparedness and subsequent prevention and control of EID events. The aim of this review is to describe tools currently available for identification, prioritization and investigation of EIDs impacting human and animal health, and how these might be integrated into a systematic approach for directing EID preparedness. Environmental scanning, foresight programmes, horizon scanning and surveillance are used to collect and assess information for rapidly responding to EIDs and to anticipate drivers of emergence for mitigating future EID impacts. Prioritization of EIDs - using transparent and repeatable methods - based on disease impacts and the importance of those impacts to decision-makers can then be used for more efficient resource allocation for prevention and control. Risk assessment and simulation modelling methods assess the likelihood of EIDs occurring, define impact and identify mitigation strategies. Each of these tools has a role to play individually; however, we propose integration of these tools into a framework that enhances the development of tactical and strategic plans for emerging risk preparedness.

  18. [Early discharge of newborns: what problems should we anticipate?].

    Straczek, H; Vieux, R; Hubert, C; Miton, A; Hascoet, J-M

    2008-06-01

    Following Nordic and Anglo-Saxon countries, France is directing towards an early discharge policy from maternity hospitals. French National Authority for Health has published recommendations focusing on the importance to highlight the dangers of such a policy so as to be able to anticipate them. To describe the complications diagnosed in the newborn infants from day 2 to the current hospital's discharge (noteworthy, if infants are discharged early, these complications may occur at home) to determine predictive factors and to validate those proposed by the French National Authority for Health. Prospective study conducted in the maternity ward of Nancy's level III facility, from January 6th to May 6th 2005. Nine hundred and three newborn infants were included. Forty-two (4.6%) presented with complications diagnosed from day 2 to hospital's discharge, among which 4 required urgent neonatal care. The most frequent complication was hyperbilirubinemia: 23 newborns were treated with phototherapy between day 2 and day 10. Statistically significant risk factors of hyperbilirubinemia after day 2 in multivariate analysis were instrumental vaginal delivery (OR=2.94; CI 95% [1.04-8.34]) and jaundice before day 2 (OR=7.39; CI 95% [2.66-20.55]). According to the French National Authority for Health's policy, 33 among 42 infants presenting with a complication would have been withdrawn from an early discharge program. In our population, French National Authority for Health's recommendations were relevant to guide an early discharge project.

  19. Anticipating Potential Waste Acceptance Criteria for Defense Spent Nuclear Fuel

    Rechard, R.P.; Lord, M.E.; Stockman, C.T.; McCurley, R.D.

    1997-01-01

    The Office of Environmental Management of the U.S. Department of Energy is responsible for the safe management and disposal of DOE owned defense spent nuclear fuel and high level waste (DSNF/DHLW). A desirable option, direct disposal of the waste in the potential repository at Yucca Mountain, depends on the final waste acceptance criteria, which will be set by DOE's Office of Civilian Radioactive Waste Management (OCRWM). However, evolving regulations make it difficult to determine what the final acceptance criteria will be. A method of anticipating waste acceptance criteria is to gain an understanding of the DOE owned waste types and their behavior in a disposal system through a performance assessment and contrast such behavior with characteristics of commercial spent fuel. Preliminary results from such an analysis indicate that releases of 99Tc and 237Np from commercial spent fuel exceed those of the DSNF/DHLW; thus, if commercial spent fuel can meet the waste acceptance criteria, then DSNF can also meet the criteria. In large part, these results are caused by the small percentage of total activity of the DSNF in the repository (1.5%) and regulatory mass (4%), and also because commercial fuel cladding was assumed to provide no protection

  20. In Wrong Anticipation - Miscalibrated Beliefs between Germans, Israelis, and Palestinians

    Goerg, Sebastian J.; Hennig-Schmidt, Heike; Walkowitz, Gari; Winter, Eyal

    2016-01-01

    The reconcilability of actions and beliefs in inter-country relationships, either in business or politics, is of vital importance as incorrect beliefs on foreigners’ behavior can have serious implications. We study a typical inter-country interaction by means of a controlled laboratory investment game experiment in Germany, Israel and Palestine involving 400 student participants in total. An investor has to take a risky decision in a foreign country that involves transferring money to an investee/allocator. We found a notable constellation of calibrated and un-calibrated beliefs. Within each country, transfer standards exist, which investees correctly anticipate within their country. However, across countries these standards differ. By attributing the standard of their own environment to the other countries investees are remarkably bad in predicting foreign investors’ behavior. The tendency to ignore this potential difference can be a source of misinterpreting motives in cross-country interaction. Foreigners might perceive behavior as unfavorable or favorable differentiation, even though—unknown to them—investors actually treat fellow-country people and foreigners alike. PMID:27311066

  1. Regulating emotion in the context of interpersonal decisions: The role of anticipated pride and regret

    Job eVan Der Schalk

    2012-11-01

    Full Text Available Recent theories about the relation between emotion and behavior hold that social behavior is influenced not only by the experience of emotion, but also by the anticipation of emotion. We argue that anticipating future emotional states is an emotion regulation strategy when it leads to a change in behavior. In the current studies we examined how construal of a fair or an unfair situation in terms of positive or negative anticipated emotions influences the fairness of subsequent behavior. We used the Ultimatum Bargaining Game--an experimental game in which participants divide a resource between themselves and another person--as a social situation that offers the opportunity to engage in fair and unfair behavior. In Study 1 we used an autobiographical recall task to manipulate anticipated emotions. Although the task did not influence anticipated emotions directly, results showed that anticipated pride about fair behavior increased levels of fairness, whereas anticipated pride about unfair behavior decreased levels of fairness. Similarly, anticipated regret about fair behavior decreased levels of fairness, whereas anticipated regret about unfair behavior increased levels of fairness. In Study 2 we replicated this pattern of findings, and found that participants who thought about their anticipated emotions (pride or regret in relation to unfair behavior behaved more fairly. We discuss these findings in relation to theories of emotion regulation and economic decision-making.

  2. Anticipation in stuttering: A theoretical model of the nature of stutter prediction.

    Garcia-Barrera, Mauricio A; Davidow, Jason H

    2015-06-01

    The fact that some people who stutter have the ability to anticipate a stuttering moment is essential for several theories of stuttering and important for maximum effectiveness of many currently used treatment techniques. The "anticipation effect," however, is poorly understood despite much investigation into this phenomenon. In the present paper, we combine (1) behavioral evidence from the stuttering-anticipation literature, (2) speech production models, and (3) models of error detection to propose a theoretical model of anticipation. Integrating evidence from theories such as Damasio's Somatic Marker Hypothesis, Levelt's Perceptual Monitoring Theory, Guenther's The Directions Into Velocities of Articulators (DIVA) model, Postma's Covert Repair Hypothesis, among others, our central thesis is that the anticipation of a stuttering moment occurs as an outcome of the interactions between previous learning experiences (i.e., learnt associations between stuttered utterances and any self-experienced or environmental consequence) and error monitoring. Possible neurological mechanisms involved in generating conscious anticipation are also discussed, along with directions for future research. The reader will be able to: (a) describe historical theories that explain how PWS may learn to anticipate stuttering; (b) state some traditional sources of evidence of anticipation in stuttering; (c) describe how PWS may be sensitive to the detection of a stuttering; (d) state some of the neural correlates that may underlie anticipation in stuttering; and (e) describe some of the possible utilities of incorporating anticipation into stuttering interventions. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. The Aube centre; Le Centre de l`Aube

    NONE

    1996-07-01

    This educational booklet is devoted to a general presentation of the Aube radioactive wastes storage centre. After a short presentation of the Andra, the French national agency for the management of radioactive wastes, it gives some general information about radioactive wastes (origin, classification), containers (quality assurance and different types), wastes transportation (planning, safety), and about the Aube centre itself: description, treatment and conditioning of drums (compacting and injection), storage facilities, geological situation of the site, and environmental controls. (J.S.)

  4. Introducing the PET Centre Prague

    Belohlavek, O.

    2001-01-01

    The PET Centre Prague (www.homolka.cz/nm) was established in 1999 as the outcome of a joint project of the public Na Homolce Hospital and the Nuclear Research Institute Rez, plc, the Czech radiopharmaceutical producer. Technical and financial assistance was provided by the International Atomic Energy Agency, which perceived the Centre as its model project that could serve as a guide for the development of PET centres in countries sharing a comparable level of development with the Czech Republic. The article maps the history of the project, its design, workplace lay-out and equipment, radiation protection arrangements and spectrum of the first approx. 3000 investigations. (author)

  5. Proximity to the treating centre and outcomes following subarachnoid hemorrhage.

    O'Kelly, Cian J; Spears, Julian; Urbach, David; Wallace, M Christopher

    2011-01-01

    In the management of subarachnoid hemorrhage (SAH), the potential for early complications and the centralization of limited resources often challenge the delivery of timely neurosurgical care. We sought to determine the impact of proximity to the accepting neurosurgical centre on outcomes following aneurysmal SAH. Using administrative data, we analyzed patients undergoing treatment for aneurysmal subarachnoid hemorrhage at neurosurgical centres in Ontario between 1995 and 2004. We compared mortality for patients receiving treatment at a centre in their county (in-county) versus those treated from outside counties (out-of-county). We also examined the impact of distance from the patient's residence to the treating centre. The mortality rates were significantly lower for in-county versus out-of-county patients (23.5% vs. 27.6%, p=0.009). This advantage remained significant after adjusting for potential confounders (HR=0.84, p=0.01). The relationship between distance from the treating centre and mortality was biphasic. Under 300 km, mortality increased with increasing distance. Over 300 km, a survival benefit was observed. Proximity to the treating neurosurgical centre impacts survival after aneurysmal SAH. These results have significant implications for the triage of these critically ill patients.

  6. Limitation of Piston Centre Shift in Free Piston Stirling Engines

    Van der Woude, R.R. [ECN Energy in the Built Environment and Networks, Petten (Netherlands)

    2006-09-15

    Piston centre shift is one of the phenomena setting Free Piston engines apart from traditional kinematic engines. In kinematic engines the piston centre position is determined by the design of the engine's internal mechanisms. In Free Piston engines however, the piston's mid-stroke position is determined by the balance of forces acting on the piston, in particular flexure and gas pressure forces. As a result, a mean pressure difference across the piston emerging during engine operation will cause the piston mid-stroke position to shift away from the geometrical centre. This process will continue until a new balance is reached with the flexure forces counteracting the new mean pressure balance. Yet, before the new equilibrium is reached, the resulting piston centre shift may have grown to such an extent that piston overstrokes have become inevitable. In order to limit piston centre shift and prevent piston overstrokes, several solutions have been proposed in the past. Popular solutions include ingenious mechanisms to vent gas between the spaces separated by the piston, in an attempt to limit the pressure difference. Enatec however has adopted a different approach by applying a precisely determined clearance between the piston and cylinder. With the right shape the clearance effectively limits the mean pressure difference across the piston and therefore limits the extent of the piston centre drift. Taking benefit of tightly controlled tolerances of both piston and cylinder, Enatec has demonstrated the effectiveness of this simple concept in series produced engines.

  7. Increased clinical anticipation with maternal transmission in benign adult familial myoclonus epilepsy in Japan.

    Hitomi, Takefumi; Kobayashi, Katsuya; Jingami, Naoto; Nakagawa, Tomokazu; Imamura, Hisaji; Matsumoto, Riki; Kondo, Takayuki; Chin, Kazuo; Takahashi, Ryosuke; Ikeda, Akio

    2013-12-01

    We recently reported clinical anticipation in Japanese families with benign adult familial myoclonus epilepsy (BAFME). However, it remains unknown whether clinical anticipation is predominantly associated with paternal or maternal transmission. We investigated the relationship between gender of the transmitting parent and clinical anticipation in nine BAFME families. Clinical anticipation regarding either cortical tremor or generalised seizures was observed in all 12 parent/child pairs (8 mother/child pairs and 4 father/child pairs). Moreover, a higher degree of clinical anticipation was associated with maternal transmission than with paternal transmission (p=0.03). Although a causative gene for BAFME still remains unknown, our finding suggests that BAFME and diseases with unstable expanding repeats, including those in non-coding regions, might share a similar molecular mechanism because such diseases often show clinical anticipation with maternal transmission.

  8. THE TIME DOMAIN SPECTROSCOPIC SURVEY: VARIABLE SELECTION AND ANTICIPATED RESULTS

    Morganson, Eric; Green, Paul J. [Harvard Smithsonian Center for Astrophysics, 60 Garden St, Cambridge, MA 02138 (United States); Anderson, Scott F.; Ruan, John J. [Department of Astronomy, University of Washington, Box 351580, Seattle, WA 98195 (United States); Myers, Adam D. [Department of Physics and Astronomy, University of Wyoming, Laramie, WY 82071 (United States); Eracleous, Michael; Brandt, William Nielsen [Department of Astronomy and Astrophysics, 525 Davey Laboratory, The Pennsylvania State University, University Park, PA 16802 (United States); Kelly, Brandon [Department of Physics, Broida Hall, University of California, Santa Barbara, CA 93106-9530 (United States); Badenes, Carlos [Department of Physics and Astronomy and Pittsburgh Particle Physics, Astrophysics and Cosmology Center (PITT PACC), University of Pittsburgh, 3941 O’Hara St, Pittsburgh, PA 15260 (United States); Bañados, Eduardo [Max-Planck-Institut für Astronomie, Königstuhl 17, D-69117 Heidelberg (Germany); Blanton, Michael R. [Center for Cosmology and Particle Physics, Department of Physics, New York University, 4 Washington Place, New York, NY 10003 (United States); Bershady, Matthew A. [Department of Astronomy, University of Wisconsin, 475 N. Charter St., Madison, WI 53706 (United States); Borissova, Jura [Instituto de Física y Astronomía, Universidad de Valparaíso, Av. Gran Bretaña 1111, Playa Ancha, Casilla 5030, and Millennium Institute of Astrophysics (MAS), Santiago (Chile); Burgett, William S. [GMTO Corp, Suite 300, 251 S. Lake Ave, Pasadena, CA 91101 (United States); Chambers, Kenneth, E-mail: emorganson@cfa.harvard.edu [Institute for Astronomy, University of Hawaii at Manoa, Honolulu, HI 96822 (United States); and others

    2015-06-20

    We present the selection algorithm and anticipated results for the Time Domain Spectroscopic Survey (TDSS). TDSS is an Sloan Digital Sky Survey (SDSS)-IV Extended Baryon Oscillation Spectroscopic Survey (eBOSS) subproject that will provide initial identification spectra of approximately 220,000 luminosity-variable objects (variable stars and active galactic nuclei across 7500 deg{sup 2} selected from a combination of SDSS and multi-epoch Pan-STARRS1 photometry. TDSS will be the largest spectroscopic survey to explicitly target variable objects, avoiding pre-selection on the basis of colors or detailed modeling of specific variability characteristics. Kernel Density Estimate analysis of our target population performed on SDSS Stripe 82 data suggests our target sample will be 95% pure (meaning 95% of objects we select have genuine luminosity variability of a few magnitudes or more). Our final spectroscopic sample will contain roughly 135,000 quasars and 85,000 stellar variables, approximately 4000 of which will be RR Lyrae stars which may be used as outer Milky Way probes. The variability-selected quasar population has a smoother redshift distribution than a color-selected sample, and variability measurements similar to those we develop here may be used to make more uniform quasar samples in large surveys. The stellar variable targets are distributed fairly uniformly across color space, indicating that TDSS will obtain spectra for a wide variety of stellar variables including pulsating variables, stars with significant chromospheric activity, cataclysmic variables, and eclipsing binaries. TDSS will serve as a pathfinder mission to identify and characterize the multitude of variable objects that will be detected photometrically in even larger variability surveys such as Large Synoptic Survey Telescope.

  9. Neurobiological underpinnings of reward anticipation and outcome evaluation in gambling disorder

    Linnet, Jakob

    2014-01-01

    Gambling disorder is characterized by persistent and recurrent maladaptive gambling behavior, which leads to clinically significant impairment or distress. The disorder is associated with dysfunctions in the dopamine system. The dopamine system codes reward anticipation and outcome evaluation....... Reward anticipation refers to dopaminergic activation prior to reward, while outcome evaluation refers to dopaminergic activation after reward. This article reviews evidence of dopaminergic dysfunctions in reward anticipation and outcome evaluation in gambling disorder from two vantage points: a model...... in gambling disorder are suggested....

  10. How Anticipated and Experienced Stigma Can Contribute to Self-Stigma: The Case of Problem Gambling

    Hing, Nerilee; Russell, Alex M. T.

    2017-01-01

    The degree to which anticipated and experienced public stigma contribute to self-stigma remains open to debate, and little research has been conducted into the self-stigma of problem gambling. This study aimed to examine which aspects of anticipated and experienced stigma (if any) predict the anticipated level of public stigma associated with problem gambling and the degree of self-stigma felt by people experiencing problem gambling. An online survey of 177 Australians experiencing problem ga...

  11. The centre of the action

    2008-01-01

    The CERN Control Centre (CCC) has all the ingredients of an action movie control room: hundreds of screens, technicians buzzing in and out, huge floor-to-ceiling windows revealing the looming vista of a mountain range, flashing lights, microphones… This is the place where not just the LHC, but the whole of CERN’s accelerator complex and technical support is based - truly the centre of the action at CERN.

  12. The CERN Data Centre readies for Run 2

    Katarina Anthony

    2015-01-01

    While the world waits for Run 2 data with growing anticipation, the CERN Data Centre is battening down the hatches. Run 2 is set to see a significant increase in the amount of data produced by the LHC experiments, with more than one hundred additional petabytes expected over the next three years. How will CERN manage this flood of results? The Bulletin checks in with the IT Department to find out...   The CERN Data Centre: the heart of CERN's entire scientific, administrative, and computing infrastructure. With every second of run-time, gigabytes of data will come pouring into the CERN Data Centre to be stored, sorted and shared with physicists worldwide. To cope with this massive influx of Run 2 data, the CERN Data and Storage Services group focused on three areas: speed, capacity and reliability. First on the list, the group set out to increase the rate at which they could store data. "During Run 1, we were storing 1 gigabyte-per-second, with the occasional peak of 6 giga...

  13. Training centres - organization and management

    Kovar, P.

    1986-01-01

    In the lecture 'Training centres - organization and management' some principles and requirements which influence the organization, management and activity pattern of nuclear training centres, are briefly introduced. It is demonstrated, step by step, how these general principles are implemented in the development of the Czechoslovak nuclear power programme, it means, how the training of the NPP personnel proceeds in Czechoslovak nuclear training centres. General principles which are selected: a connection between the capacity of the training centre and the scope and needs of the nuclear power programme, a position of the training center within the institutional set-up, a structure and organization of the training system which complies with the system of NPP construction, reflect the pattern and the activity of the nuclear training centre and nuclear power technical level, a research group of workers in the nuclear training centre, main tasks and technical facilities, management of the training process and a transfer of knowledge and research results into the training process. The lecture is supplemented by pictures and slides. (orig.)

  14. RTEMS Centre - Support and Maintenance Centre to RTEMS Operating System

    Silva, H.; Constantino, A.; Freitas, D.; Coutinho, M.; Faustino, S.; Mota, M.; Colaço, P.; Sousa, J.; Dias, L.; Damjanovic, B.; Zulianello, M.; Rufino, J.

    2009-05-01

    RTEMS CENTRE - Support and Maintenance Centre to RTEMS Operating System is a joint ESA/Portuguese Task Force initiative to develop a support and maintenance centre to the Real-Time Executive for Multiprocessor Systems (RTEMS). This paper gives a high level visibility of the progress, the results obtained and the future work in the RTEMS CENTRE [6] and in the RTEMS Improvement [7] projects. RTEMS CENTRE started officially in November 2006, with the RTEMS 4.6.99.2 version. A full analysis of RTEMS operating system was produced. The architecture was analysed in terms of conceptual, organizational and operational concepts. The original objectives [1] of the centre were primarily to create and maintain technical expertise and competences in this RTOS, to develop a website to provide the European Space Community an entry point for obtaining support (http://rtemscentre.edisoft.pt), to design, develop, maintain and integrate some RTEMS support tools (Timeline Tool, Configuration and Management Tools), to maintain flight libraries and Board Support Packages, to develop a strong relationship with the World RTEMS Community and finally to produce some considerations in ARINC-653, DO-178B and ECSS E-40 standards. RTEMS Improvement is the continuation of the RTEMS CENTRE. Currently the RTEMS, version 4.8.0, is being facilitated for a future qualification. In this work, the validation material is being produced following the Galileo Software Standards Development Assurance Level B [5]. RTEMS is being completely tested, errors analysed, dead and deactivated code removed and tests produced to achieve 100% statement and decision coverage of source code [2]. The SW to exploit the LEON Memory Management Unit (MMU) hardware will be also added. A brief description of the expected implementations will be given.

  15. QUANTIFYING BENEFITS FOR COST-BENEFIT ANALYSIS

    Attila GYORGY; Nicoleta VINTILA; Florian GAMAN

    2014-01-01

    Cost Benefit Analysis is one of the most widely used financial tools to select future investment projects in public and private sector. This method is based on comparing costs and benefits in terms of constant prices. While costs are easier to predict and monetize, the benefits should be identified not only in direct relation with the investment, but also widening the sphere of analysis to indirect benefits experienced by the community from the neighbourhood or the whole society. During finan...

  16. Anticipating the uncertain: economic modeling and climate change policy

    Jensen, Svenn

    2012-11-01

    With this thesis I wish to contribute to the understanding of how uncertainty and the anticipation of future events by economic actors affect climate policies. The thesis consists of four papers. Two papers are analytical models which explicitly consider that emissions are caused by extracting scarce fossil fuels which in the future must be replaced by clean technologies. The other two are so called numerical integrated assessment models. Such models represent the world economy, the climate system and the interactions between those two quantitatively, complementing more abstract theoretical work. Should policy makers discriminate between subsidizing renewable energy sources such as wind or solar power, and technologies such as carbon capture and storage (CCS)? Focusing only on the dynamic supply of fossil fuels and hence Co{sub 2}, we find here that cheaper future renewables cause extraction to speed up, lower costs of CCS may delay it. CCS hence may dampen the dynamic inefficiency caused by the absence of comprehensive climate policies today. Does it matter whether uncertainty about future damage assessment is due to scientific complexities or stems from the political process? In paper two, I find that political and scientific uncertainties have opposing effects on the incentives to investment in renewables and the extraction of fossil fuels: The prospect of scientific learning about the climate system increases investment incentives and, ceteris paribus, slows extraction down; uncertainty about future political constellations does the opposite. The optimal carbon tax under scientific uncertainty equals expected marginal damages, whereas political uncertainty demands a tax below marginal damages that decreases over time. Does uncertainty about economic growth impact optimal climate policy today? Here we are the first to consistently analyze how uncertainty about future economic growth affects optimal emission reductions and the optimal social cost of carbon. We

  17. Anticipating Interruptions. Security and risk in a liberalized electricity infrastructure

    Silvast, A.

    2013-11-01

    During the past ten years, a number of social scientists have emphasized the importance of material infrastructures like electricity supply as a research topic for the social sciences. The developing of such new perspectives concerning infrastructures also includes uncertainties and risks. This research analyzes the management of uncertainties in the Finnish electricity infrastructure by posing the following research question: how are electricity interruptions, or blackouts, anticipated in Finland and how are these interruptions managed as risks? The main research methodology of the work is multi-sited field work. The empirical materials include interviews with experts and lay people (33 interviews); participant observation in two electricity control rooms; an electricity consumer survey (115 respondents); and also a number of infrastructure and security policy documents and observations from electricity security seminars. The materials were primarily gathered between 2004 and 2008. Social science research often links risks with major current social changes or socio-cultural risk perceptions. In recent international social science discussions, however, a new research topic has emerged - those styles of reasoning and techniques of governance that are deployed to manage risk as a practical matter. My study explores these themes empirically by focusing on the specific habitual practices of risk management in the Finnish electricity infrastructure. The work develops various also semi-ethnographic inquiries into infrastructure risk techniques like monitor screening of real-time risks in electricity control rooms; the management of risks in a liberalized electricity market; the emergence of Finnish reasoning about blackouts from a specific historical background; and the ways in which electricity consumers respond to blackouts in their homes. In addition, the work reflects upon the position of a risk researcher in those situations when the research subjects do not define

  18. To study the existing system of surgical safety for cataract surgery at tertiary care ophthalmic centre to implement WHO surgical safety checklist

    Ruchi Garg; Neeraj Garg; Shakti Kumar Gupta; J. S. Titiyal; R. Mahesh

    2016-01-01

    Background: Dr. Rajendra Prasad Centre for Ophthalmic Sciences, named after the first President of India, was established on the 10th of March, 1967 as a National centre for ophthalmic science, to provide state of the art patient care, expand human resources for medical education and undertake research to find solutions to eye health problems of national importance. Average numbers of cataract surgeries performed per month are 700 to 1000. Methods: Anticipating implementation in 50% cases...

  19. A survey of current and anticipated use of standard and specialist equipment by UK optometrists.

    Dabasia, Priya L; Edgar, David F; Garway-Heath, David F; Lawrenson, John G

    2014-09-01

    To investigate current and anticipated use of equipment and information technology (IT) in community optometric practice in the UK, and to elicit optometrists' views on adoption of specialist equipment and IT. An anonymous online questionnaire was developed, covering use of standard and specialist diagnostic equipment, and IT. The survey was distributed to a random sample of 1300 UK College of Optometrists members. Four hundred and thirty-two responses were received (response rate = 35%). Enhanced (locally commissioned) or additional/separately contracted services were provided by 73% of respondents. Services included glaucoma repeat measures (30% of respondents), glaucoma referral refinement (22%), fast-track referral for wet age-related macular degeneration (48%), and direct cataract referral (40%). Most respondents (88%) reported using non-contact/pneumo tonometry for intra-ocular pressure measurement, with 81% using Goldmann or Perkins tonometry. The most widely used item of specialist equipment was the fundus camera (74% of respondents). Optical Coherence Tomography (OCT) was used by 15% of respondents, up from 2% in 2007. Notably, 43% of those anticipating purchasing specialist equipment in the next 12 months planned to buy an OCT. 'Paperless' records were used by 39% of respondents, and almost 80% of practices used an electronic patient record/practice management system. Variations in responses between parts of the UK reflect differences in the provision of the General Ophthalmic Services contract or community enhanced services. There was general agreement that specialised equipment enhances clinical care, permits increased involvement in enhanced services, promotes the practice and can be used as a defence in clinico-legal cases, but initial costs and ongoing maintenance can be a financial burden. Respondents generally agreed that IT facilitates administrative flow and secure exchange of health information, and promotes a state-of-the-art practice image

  20. Outcome of physiotherapy after surgery for cervical disc disease: a prospective randomised multi-centre trial

    2014-01-01

    Background Many patients with cervical disc disease require leave from work, due to long-lasting, complex symptoms, including chronic pain and reduced levels of physical and psychological function. Surgery on a few segmental levels might be expected to resolve disc-specific pain and reduce neurological deficits, but not the non-specific neck pain and the frequent illness. No study has investigated whether post-surgery physiotherapy might improve the outcome of surgery. The main purpose of this study was to evaluate whether a well-structured rehabilitation programme might add benefit to the customary post-surgical treatment for cervical disc disease, with respect to function, disability, work capability, and cost effectiveness. Methods/Design This study was designed as a prospective, randomised, controlled, multi-centre study. An independent, blinded investigator will compare two alternatives of rehabilitation. We will include 200 patients of working age, with cervical disc disease confirmed by clinical findings and symptoms of cervical nerve root compression. After providing informed consent, study participants will be randomised to one of two alternative physiotherapy regimes; (A) customary treatment (information and advice on a specialist clinic); or (B) customary treatment plus active physiotherapy. Physiotherapy will follow a standardised, structured programme of neck-specific exercises combined with a behavioural approach. All patients will be evaluated both clinically and subjectively (with questionnaires) before surgery and at 6 weeks, 3 months, 6 months, 12 months, and 24 months after surgery. The main outcome variable will be neck-specific disability. Cost-effectiveness will also be calculated. Discussion We anticipate that the results of this study will provide evidence to support physiotherapeutic rehabilitation applied after surgery for cervical radiculopathy due to cervical disc disease. Trial registration ClinicalTrials.gov identifier: NCT01547611

  1. Developing a Stakeholder-Driven Anticipated Timeline of Impact for Evaluation of Social Programs

    Sridharan, Sanjeev; Campbell, Bernadette; Zinzow, Heidi

    2006-01-01

    The authors present a stakeholder-driven method, the earliest anticipated timeline of impact, which is designed to assess stakeholder expectations for the earliest time frame in which social programs are likely to affect outcomes. The utility of the anticipated timeline of impact is illustrated using an example from an evaluation of a…

  2. Steeling Ourselves : Intragroup Communication while Anticipating Intergroup Contact Evokes Defensive Intergroup Perceptions

    Greijdanus, Hedy; Postmes, Tom; Gordijn, Ernestine H.; van Zomeren, Martijn

    2015-01-01

    Two experiments investigated the role of intragroup communication in intergroup conflict (de-)escalation. Experiment 1 examined the effects of intragroup communication (vs. individual thought) and anticipated face-to-face intergroup contact (vs. no anticipated face-to-face intergroup contact). The

  3. The influence of anticipated pride and guilt on pro-environmental decision making

    Zaval, Lisa; Weber, Elke U.; Markowitz, Ezra M.

    2017-01-01

    The present research explores the relationship between anticipated emotions and pro-environmental decision making comparing two differently valenced emotions: anticipated pride and guilt. In an experimental design, we examined the causal effects of anticipated pride versus guilt on pro-environmental decision making and behavioral intentions by making anticipated emotions (i.e. pride and guilt) salient just prior to asking participants to make a series of environmental decisions. We find evidence that anticipating one’s positive future emotional state from green action just prior to making an environmental decision leads to higher pro-environmental behavioral intentions compared to anticipating one’s negative emotional state from inaction. This finding suggests a rethinking in the domain of environmental and climate change messaging, which has traditionally favored inducing negative emotions such as guilt to promote pro-environmental action. Furthermore, exploratory results comparing anticipated pride and guilt inductions to baseline behavior point toward a reactance eliciting effect of anticipated guilt. PMID:29190758

  4. 32 CFR 806b.19 - Information compiled in anticipation of civil action.

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Information compiled in anticipation of civil action. 806b.19 Section 806b.19 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR... compiled in anticipation of civil action. Withhold records compiled in connection with a civil action or...

  5. The relative importance of different perceptual-cognitive skills during anticipation.

    North, Jamie S; Hope, Ed; Williams, A Mark

    2016-10-01

    We examined whether anticipation is underpinned by perceiving structured patterns or postural cues and whether the relative importance of these processes varied as a function of task constraints. Skilled and less-skilled soccer players completed anticipation paradigms in video-film and point light display (PLD) format. Skilled players anticipated more accurately regardless of display condition, indicating that both perception of structured patterns between players and postural cues contribute to anticipation. However, the Skill×Display interaction showed skilled players' advantage was enhanced in the video-film condition, suggesting that they make better use of postural cues when available during anticipation. We also examined anticipation as a function of proximity to the ball. When participants were near the ball, anticipation was more accurate for video-film than PLD clips, whereas when the ball was far away there was no difference between viewing conditions. Perceiving advance postural cues appears more important than structured patterns when the ball is closer to the observer, whereas the reverse is true when the ball is far away. Various perceptual-cognitive skills contribute to anticipation with the relative importance of perceiving structured patterns and advance postural cues being determined by task constraints and the availability of perceptual information. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Awake fiberoptic or awake video laryngoscopic tracheal intubation in patients with anticipated difficult airway management

    Rosenstock, Charlotte Vallentin; Thøgersen, Bente; Afshari, Arash

    2012-01-01

    Awake flexible fiberoptic intubation (FFI) is the gold standard for management of anticipated difficult tracheal intubation. The purpose of this study was to compare awake FFI to awake McGrath® video laryngoscope, (MVL), (Aircraft Medical, Edinburgh, Scotland, United Kingdom) intubation in patients...... with an anticipated difficult intubation. The authors examined the hypothesis that MVL intubation would be faster than FFI....

  7. Motor Anticipation Failure in Infants with Autism: A Retrospective Analysis of Feeding Situations

    Brisson, Julie; Warreyn, Petra; Serres, Josette; Foussier, Stephane; Adrien-Louis, Jean

    2012-01-01

    Previous studies on autism have shown a lack of motor anticipation in children and adults with autism. As part of a programme of research into early detection of autism, we focussed on an everyday situation: spoon-feeding. We hypothesize that an anticipation deficit may be found very early on by observing whether the baby opens his or her mouth in…

  8. Brain Activity during Methamphetamine Anticipation in a Non-Invasive Self-Administration Paradigm in Mice.

    Juárez-Portilla, Claudia; Pitter, Michael; Kim, Rachel D; Patel, Pooja Y; Ledesma, Robert A; LeSauter, Joseph; Silver, Rae

    2018-01-01

    The ability to sense time and anticipate events is critical for survival. Learned responses that allow anticipation of the availability of food or water have been intensively studied. While anticipatory behaviors also occur prior to availability of regularly available rewards, there has been relatively little work on anticipation of drugs of abuse, specifically methamphetamine (MA). In the present study, we used a protocol that avoided possible CNS effects of stresses of handling or surgery by testing anticipation of MA availability in animals living in their home cages, with daily voluntary access to the drug at a fixed time of day. Anticipation was operationalized as the amount of wheel running prior to MA availability. Mice were divided into four groups given access to either nebulized MA or water, in early or late day. Animals with access to MA, but not water controls, showed anticipatory activity, with more anticipation in early compared to late day and significant interaction effects. Next, we explored the neural basis of the MA anticipation, using c-FOS expression, in animals euthanized at the usual time of nebulization access. In the dorsomedial hypothalamus (DMH) and orbitofrontal cortex (OFC), the pattern of c-FOS expression paralleled that of anticipatory behavior, with significant main and interaction effects of treatment and time of day. The results for the lateral septum (LS) were significant for main effects and marginally significant for interaction effects. These studies suggest that anticipation of MA is associated with activation of brain regions important in circadian timing, emotional regulation, and decision making.

  9. Anticipation increases tactile stimulus processing in the ipsilateral primary somatosensory cortex.

    van Ede, Freek; de Lange, Floris P; Maris, Eric

    2014-10-01

    Stimulus anticipation improves perception. To account for this improvement, we investigated how stimulus processing is altered by anticipation. In contrast to a large body of previous work, we employed a demanding perceptual task and investigated sensory responses that occur beyond early evoked activity in contralateral primary sensory areas: Stimulus-induced modulations of neural oscillations. For this, we recorded magnetoencephalography in 19 humans while they performed a cued tactile identification task involving the identification of either a proximal or a distal stimulation on the fingertips. We varied the cue-target interval between 0 and 1000 ms such that tactile targets occurred at various degrees of anticipation. This allowed us to investigate the influence of anticipation on stimulus processing in a parametric fashion. We observed that anticipation increases the stimulus-induced response (suppression of beta-band oscillations) originating from the ipsilateral primary somatosensory cortex. This occurs in the period in which the tactile memory trace is analyzed and is correlated with the anticipation-induced improvement in tactile perception. We propose that this ipsilateral response indicates distributed processing across bilateral primary sensory cortices, of which the extent increases with anticipation. This constitutes a new and potentially important mechanism contributing to perception and its improvement following anticipation. © The Author 2013. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  10. Probability effects in anticipation investigated with online behavioural measures (mouse tracking)

    Bruhn, Pernille; Bærentsen, Klaus B.

    Background: Anticipation of upcoming events is an adaptive mechanism that ensures quick and accurate perception and action. Consequently, lower Reaction Time (RT) and higher accuracy is found in response to events that can be adequately anticipated. However, events in the world happen with varying...

  11. Anticipation, Teamwork, and Cognitive Load: Chasing Efficiency during Robot-Assisted Surgery

    Sexton, Kevin; Johnson, Amanda; Gotsch, Amanda; Hussein, Ahmed A.; Cavuoto, Lora; Guru, Khurshid A.

    2018-01-01

    Introduction Robot-assisted surgery (RAS) has changed the traditional operating room, occupying more space with equipment and isolating console surgeons away from the patients and their team. We aimed to evaluate how anticipation of surgical steps and familiarity between team members impacted efficiency and safety. Methods We analyzed recordings (video and audio) of 12 robot-assisted radical prostatectomies. Any requests between surgeon and the team members were documented and classified by personnel, equipment type, mode of communication, level of inconvenience in fulfilling the request, and anticipation. Surgical team members completed questionnaires assessing team familiarity and cognitive load (NASA-TLX). Predictors of team efficiency were assessed using Pearson correlation and stepwise linear regression. Results 1330 requests were documented of which 413 (31%) were anticipated. Anticipation correlated negatively with operative time resulting in overall 8% reduction of OR time. Team familiarity negatively correlated with inconveniences. Anticipation ratio, percent of requests that were nonverbal, and total request duration were significantly correlated with the console surgeons’ cognitive load (r=0.77, p=0.006; r=0.63, p=0.04; and r=0.70, p=0.02, respectively). Conclusions Anticipation and active engagement by the surgical team resulted in shorter operative time; and higher familiarity scores were associated with fewer inconveniences. Less anticipation and nonverbal requests were also associated with lower cognitive load for the console surgeon. Training efforts to increase anticipation and team familiarity can improve team efficiency during RAS. PMID:28689193

  12. Contributions from eye movement potentials to stimulus preceding negativity during anticipation of auditory stimulation

    Engdahl, Lis; Bjerre, Vicky K; Christoffersen, Gert R J

    2007-01-01

    Cognitive anticipation of a stimulus has been associated with an ERP called "stimulus preceding negativity" (SPN). A new auditory delay task without stimulus-related motor activity demonstrated a prefrontal SPN, present during attentive anticipation of sounds with closed eyes, but absent during d...

  13. Anticipated Ongoing Interaction versus Channel Effects of Relational Communication in Computer-Mediated Interaction.

    Walther, Joseph B.

    1994-01-01

    Assesses the related effects of anticipated future interaction and different communication media (computer-mediated versus face-to-face communication) on the communication of relational intimacy and composure. Shows that the assignment of long-term versus short-term partnerships has a larger impact on anticipated future interaction reported by…

  14. parkin mutation dosage and the phenomenon of anticipation: a molecular genetic study of familial parkinsonism

    Schellenberg Gerard D

    2005-02-01

    Full Text Available Abstract Background parkin mutations are a common cause of parkinsonism. Possessing two parkin mutations leads to early-onset parkinsonism, while having one mutation may predispose to late-onset disease. This dosage pattern suggests that some parkin families should exhibit intergenerational variation in age at onset resembling anticipation. A subset of familial PD exhibits anticipation, the cause of which is unknown. The aim of this study was to determine if anticipation was due to parkin mutation dosage. Methods We studied 19 kindreds that had early-onset parkinsonism in the offspring generation, late-onset parkinsonism in the parent generation, and ≥ 20 years of anticipation. We also studied 28 early-onset parkinsonism cases without anticipation. Patients were diagnosed by neurologists at a movement disorder clinic. parkin analysis included sequencing and dosage analysis of all 12 exons. Results Only one of 19 cases had compound parkin mutations, but contrary to our postulate, the affected relative with late-onset parkinsonism did not have a parkin mutation. In effect, none of the anticipation cases could be attributed to parkin. In contrast, 21% of early-onset parkinsonism patients without anticipation had parkin mutations. Conclusion Anticipation is not linked to parkin, and may signify a distinct disease entity.

  15. The ideal Atomic Centre; Le Centre Atomique ideal

    Mas, R [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1965-07-01

    The author presents considerations which should prove to be of interest to all those who have to design, to construct and to operate a nuclear research centre. A large number of the ideas presented can also be applied to non-nuclear scientific research centres. In his report the author reviews: various problems with which the constructor is faced: ground-plan, infrastructure, buildings and the large units of scientific equipment in the centre, and those problems facing the director: maintenance, production, supplies, security. The author stresses the relationship which ought to exist between the research workers and the management. With this aim in view he proposes the creation of National School for Administration in Research which would train administrative executives for public or private organisations; they would be specialised in the fields of fundamental or applied research. (author) [French] L'auteur propose une base de reflexions a tous ceux qui doivent concevoir, realiser et faire vivre un Centre d'Etudes Nucleaires. Un grand nombre des idees exprimees peut d'ailleurs s'appliquer a un Centre d'Etudes Scientifiques non nucleaires. Dans son ouvrage, l'auteur passe en revue les differents problemes qui se posent au constructeur: plan, masse, infrastructure, batiments et grands appareils du Centre, et ceux qu'a a resoudre le directeur: entretien, fabrication, approvisionnements, securite. L'auteur insiste sur l'aspect des rapports qui doivent exister entre les chercheurs et ceux qui les administrent. Il propose a cette fin la creation d'une Ecole Nationale d'Administration de la Recherche qui formerait des cadres administratifs pour les organismes publics ou prives, specialises dans la Recherche fondamentale ou appliquee. (auteur)

  16. Amygdala response to anticipation of dyspnea is modulated by 5-HTTLPR genotype.

    Stoeckel, M Cornelia; Esser, Roland W; Gamer, Matthias; Kalisch, Raffael; Büchel, Christian; von Leupoldt, Andreas

    2015-07-01

    Dyspnea anticipation and perception varies largely between individuals. To investigate whether genetic factors related to negative affect such as the 5-HTTLPR polymorphism impact this variability, we investigated healthy, 5-HTTLPR stratified volunteers using resistive load induced dyspnea together with fMRI. Alternating blocks of severe and mild dyspnea ("perception") were differentially cued ("anticipation") and followed by intensity and unpleasantness ratings. In addition, volunteers indicated their anticipatory fear during the anticipation periods. There were no genotype-based group differences concerning dyspnea intensity and unpleasantness or brain activation during perception of severe vs. mild dyspnea. However, in risk allele carriers, higher anticipatory fear was paralleled by stronger amygdala activation during anticipation of severe vs. mild dyspnea. These results suggest a role of the 5-HTTLPR genotype in fearful dyspnea anticipation. © 2015 Society for Psychophysiological Research.

  17. Mimicking and anticipating others’ actions is linked to Social Information Processing

    Klomfar, Sophie; d’Haene, Ine; Brass, Marcel

    2018-01-01

    It is widely known that individuals frequently imitate each other in social situations and that such mimicry fulfills an important social role in the sense that it functions as a social glue. With reference to the anticipated action effect, it has recently been demonstrated that individuals do not only imitate others, but also engage in anticipated action before the observed person starts engaging in that action. Interestingly, both phenomena (i.e., mimicry and anticipated action) rely on tracking others’ social behavior. Therefore, in the present research we investigated whether mimicry and anticipated action are related to social abilities as indicated by measures of social intelligence. The results demonstrate for the first time that mimicry as well as anticipated action is correlated with an important aspect of social intelligence—namely the ability to process social information. Theoretical implications and limitations are discussed. PMID:29590127

  18. Benefits of Java

    ... Wellness Preventing Illness Benefits of Coffee Print Email Benefits of Coffee Reviewed by Taylor Wolfram, MS, RDN, ... your daily cup (or three) provides some health benefits as well. Drinking moderate amounts of coffee (including ...

  19. Benefits of quitting tobacco

    ... your risk of many serious health problems . THE BENEFITS OF QUITTING You may enjoy the following when ... about $2,000 a year on cigarettes. HEALTH BENEFITS Some health benefits begin almost immediately. Every week, ...

  20. School uniforms: tradition, benefit or predicament?

    Van Aardt, Annette Marie; Wilken, Ilani

    2012-01-01

    This article focuses on the controversies surrounding school uniforms. Roleplayers in this debate in South Africa are parents, learners and educators, and arguments centre on aspects such as identity, economy and the equalising effect of school uniforms, which are considered in the literature to be benefits. Opposing viewpoints highlight the fact that compulsory uniforms infringe on learners’ constitutional rights to self-expression. The aim of this research was to determine the perspectives ...

  1. How stakeholders frame dam removal: The role of current and anticipated future ecosystem service use

    Reilly, Kate; Adamowski, Jan

    2016-04-01

    Many river restoration projects, including dam removal, are controversial and can trigger conflicts between stakeholders who are for and against the proposed project. The study of environmental conflicts suggests that differences in how stakeholders 'frame', or make sense of a situation based on their prior knowledge and experiences, can perpetuate conflicts. Understanding different stakeholders' frames, particularly how they converge, can form the basis of successful conflict resolution. In the case of dam removals, it is often assumed that emphasising increased provision of ecosystem services can be a point of convergence between those advocating for ecological restoration and those opposed to removal because of negative human impacts. However, how exactly stakeholders frame a contentious proposed dam removal and how those frames relate to ecosystem services has been little studied. Here we used the case of a potential dam removal in New Brunswick to investigate how people frame the issue and how that relates to their current and anticipated future use of ecosystem services. Based on in-depth interviews with 30 stakeholders in the area, including both people for and against dam removal, we found that both groups currently used ecosystem services and were in favour of ecosystem protection. However, they differed in how they framed the issue of the potential dam removal. The group against dam removal framed the issue as one of loss and risk - they thought that any potential benefits to the ecosystem would be outweighed by the high risk of negative social impacts caused by a loss of access to ecosystem services, such as recreation and aesthetic enjoyment. By contrast, the group in favour of the dam framed the issue as one of opportunity and justice. They thought that following a short transition period, all stakeholders would benefit from the restored river, particularly from a restored salmon fishery, improved aesthetic appeal and the long-term sustainability of an

  2. Electronics Environmental Benefits Calculator

    U.S. Environmental Protection Agency — The Electronics Environmental Benefits Calculator (EEBC) was developed to assist organizations in estimating the environmental benefits of greening their purchase,...

  3. The Belgian nuclear research centre

    Moons, F.

    2001-01-01

    The Belgian Nuclear Research Centre is almost exclusively devoted to nuclear R and D and services and is able to generate 50% of its resources (out of 75 million Euro) by contract work and services. The main areas of research include nuclear reactor safety, radioactive waste management, radiation protection and safeguards. The high flux reactor BR2 is extensively used to test fuel and structural materials. PWR-plant BR3 is devoted to the scientific analysis of decommissioning problems. The Centre has a strong programme on the applications of radioisotopes and radiation in medicine and industry. The centre has plans to develop an accelerator driven spallation neutron source for various applications. It has initiated programmes to disseminate correct information on issues of nuclear energy production and non-energy nuclear applications to different target groups. It has strong linkages with the IAEA, OECD-NEA and the Euratom. (author)

  4. Technical support and emergency centre

    Bohun, L.; Kapisovsk y, M.

    1997-01-01

    This paper presents technical support and emergency management center which will be on two places: Mochovce NPP Emergency Centre (Technical support center and Support working center) and Reserve Emergency Centre in Levice (Reserve emergency center and Environmental Evaluation Center). The main aims of the emergency management centers are: the management and coordination of all persons and organisations; provision of the all information needed to evaluation of the accident and its mitigation; continuous evaluation of the potential or real radiological consequences; taking measure for an early notification of the governmental bodies and the organizations, warning and protection of the public; and other aims. In the next part the data for technical support and emergency centre are discussed

  5. Presentation of TVO's visitor's centre

    Aemmaelae, V.M.

    1993-01-01

    There are four nuclear power plant units in Finland, two of which are PWR's owned by Imatran Voima Oy. The two BWR units are located at Olkiluoto and owned by Teollisuuden Voima Oy. This presentation tells about TVO's concept of informing the visitors at Olkiluoto. At the site there are located, in addition to the two nuclear power plant units, the intermediate storage for spent fuel, the repository for low and medium-active waste as well as the training centre. At the Olkiluoto Visitor's Centre all the activities of the company are presented using varied audio-visual aids. The centre has several exhibits and there are also different installations to show how the plant works. (author)

  6. CLIMATE CHANGE – BETWEEN COSTS AND BENEFITS

    CARMEN VALENTINA RĂDULESCU

    2011-03-01

    Full Text Available Climate change – between costs and benefits. At global and regional levels the effects of climate change start to show up. While some of the countries make efforts to alleviate these effects and to find solutions, others are facing economic or political restrains that prevent them in applying the principle of common responsibility. The complex social, economic, and environmental implications of climate change’s effects focused a growing part of research on the analysis of costs and benefits. Although controversial, one of the methods used – the cost-benefit analysis – revealed that in most of the cases the prevention costs are lower than the costs of inaction. Prevention measures bring benefits by anticipating the impact and minimizing the risks for ecosystems and economy. The paper presents in its first part the controversies regarding the cost-benefit analysis, and continues, in the second part, with estimations on costs and benefits of certain policy instruments that target emission reduction.

  7. Maximising value from a United Kingdom Biomedical Research Centre: study protocol.

    Greenhalgh, Trisha; Ovseiko, Pavel V; Fahy, Nick; Shaw, Sara; Kerr, Polly; Rushforth, Alexander D; Channon, Keith M; Kiparoglou, Vasiliki

    2017-08-14

    Biomedical Research Centres (BRCs) are partnerships between healthcare organisations and universities in England. Their mission is to generate novel treatments, technologies, diagnostics and other interventions that increase the country's international competitiveness, to rapidly translate these innovations into benefits for patients, and to improve efficiency and reduce waste in healthcare. As NIHR Oxford BRC (Oxford BRC) enters its third 5-year funding period, we seek to (1) apply the evidence base on how best to support the various partnerships in this large, multi-stakeholder research system and (2) research how these partnerships play out in a new, ambitious programme of translational research. Organisational case study, informed by the principles of action research. A cross-cutting theme, 'Partnerships for Health, Wealth and Innovation' has been established with multiple sub-themes (drug development, device development, business support and commercialisation, research methodology and statistics, health economics, bioethics, patient and public involvement and engagement, knowledge translation, and education and training) to support individual BRC research themes and generate cross-theme learning. The 'Partnerships' theme will support the BRC's goals by facilitating six types of partnership (with patients and citizens, clinical services, industry, across the NIHR infrastructure, across academic disciplines, and with policymakers and payers) through a range of engagement platforms and activities. We will develop a longitudinal progress narrative centred around exemplar case studies, and apply theoretical models from innovation studies (Triple Helix), sociology of science (Mode 2 knowledge production) and business studies (Value Co-creation). Data sources will be the empirical research studies within individual BRC research themes (who will apply separately for NHS ethics approval), plus documentary analysis and interviews and ethnography with research

  8. International Development Research Centre Act Loi sur le Centre de ...

    1 juin 2009 ... research includes any scientific or technical inquiry or experimentation that is .... data centres and facilities for research and other activ- ities;. (b) initiate and ..... Loi sur la pension de la fonction publique ne s'applique pas aux ...

  9. Scheduling participants of Assessment Centres

    Lysgaard, Jens; Løber, Janni

      Assessment Centres are used as a tool for psychologists and coaches to observe a number of dimensions in a person's behaviour and test his/her potential within a number of chosen focus areas. This is done in an intense course, with a number of different exercises which expose each participant...... Centres usually last two days and involve 3-6 psychologists or trained coaches as assessors. An entire course is composed of a number of rounds, with each round having its individual duration. In each round, the participants are divided into a number of groups with prespecifed pairing of group sizes...

  10. Training centres in Latin America

    NONE

    1959-04-15

    Early 1958 the Brazilian representative on the Board of Governors of the International Atomic Energy Agency - supported by the Governors from Argentina and Guatemala -proposed that a study should be made of the possibility of setting up one or more atomic energy training centres in Latin America. On the Board's recommendation, the Director General of the Agency appointed a fact-finding team to make anon-the-spot study. In drafting this report the team was invited to consider the following points: (a) The need for establishing one or more regional training centres; (b) Existing facilities that are being or could be used for training, together with technical data concerning them; (c) The general scientific technological and industrial conditions of the countries visited insofar as they have a bearing on their training needs and capabilities. The authors of the report conclude that 'a training centre in radio-botany should provide vitally needed knowledge and vitally needed specialists to all the agricultural installations in Latin America. A training centre like this might provide an excellent model upon which to base training centres in other areas'. The report recommends that: 1. The Agency should meet the requests of Latin American universities by, for example, supplying equipment and sending experts; 2. At least one specialized training centre should be established as soon as possible. Taking as an example the field of radio-botany, such a centre would provide trained specialists in radio-botany to agricultural institutions throughout Latin America and also provide basic research results vital to agriculture. The cost of new facilities might be of the order of $7 500 000, with an annual budget of approximately $650 000. Staff required: 40 scientists and 175 employees; 3. Whenever it appears feasible to gather necessary staff of high creative ability and established productivity and when funds can be made available for facilities, equipment and operating costs, at

  11. Training centres in Latin America

    1959-01-01

    Early 1958 the Brazilian representative on the Board of Governors of the International Atomic Energy Agency - supported by the Governors from Argentina and Guatemala -proposed that a study should be made of the possibility of setting up one or more atomic energy training centres in Latin America. On the Board's recommendation, the Director General of the Agency appointed a fact-finding team to make anon-the-spot study. In drafting this report the team was invited to consider the following points: (a) The need for establishing one or more regional training centres; (b) Existing facilities that are being or could be used for training, together with technical data concerning them; (c) The general scientific technological and industrial conditions of the countries visited insofar as they have a bearing on their training needs and capabilities. The authors of the report conclude that 'a training centre in radio-botany should provide vitally needed knowledge and vitally needed specialists to all the agricultural installations in Latin America. A training centre like this might provide an excellent model upon which to base training centres in other areas'. The report recommends that: 1. The Agency should meet the requests of Latin American universities by, for example, supplying equipment and sending experts; 2. At least one specialized training centre should be established as soon as possible. Taking as an example the field of radio-botany, such a centre would provide trained specialists in radio-botany to agricultural institutions throughout Latin America and also provide basic research results vital to agriculture. The cost of new facilities might be of the order of $7 500 000, with an annual budget of approximately $650 000. Staff required: 40 scientists and 175 employees; 3. Whenever it appears feasible to gather necessary staff of high creative ability and established productivity and when funds can be made available for facilities, equipment and operating costs, at

  12. Logistics centres development in Latvia

    I. Kabashkin

    2007-12-01

    Full Text Available In the situation where a large increase in trade and freight transport volumes in the Baltic Sea region (BSR is expected and in which the BSR is facing a major economic restructuring, eff orts to achieve more integrated and sustainable transport and communication links within the BSR are needed. One of these eff orts is the development of logistics centres (LCs and their networking, which will continue to have an impact on improving communication links, spatial planning practices and approaches, logistics chain development and the promotion of sustainable transport modes. These factors will refl ect on logistics processes both in major gateway cities and in remote BSR areas. The importance of logistics systems as a whole is not seen clearly enough. Logistics actors see that logistics operations are not appreciated as much as other fi elds of activity. In addition, logistics centres and the importance of logistics activities to the business life of areas and the employment rate should be brought up better. In the paper main goal and tasks of national approach to LCs development are discussed. Strategic focus of new activities in this area is on the integration of various networks within and between logistics centres in order to improve and develop the quality of logistics networks as well as to spatially widen the networking activities. The key objectives are to integrate the links between logistics centres, ports and other logistics operators in a functional and sustainable way, to promote spatial integration by creating sustainable and integrated approaches to spatial planning of logistics centres and transport infrastructure, to improve ICT-based networking and communication practices of the fi elds of transport and logistics and to increase the competence of logistics centres and associated actors by organising educational and training events. The current activities include, for example, the creation of measures for transport networking and

  13. Strategy development for anticipating and handling a disruptive technology.

    Chan, Stephen

    2006-10-01

    The profession of radiology has greatly benefited from the introduction of new imaging technologies throughout its history. Therefore, it would seem reasonable for radiologists to believe that the emergence of a new imaging technology can generally be foreseen with sufficient advance notice to allow the appropriate levels of time, effort, and money to be devoted toward incorporating it into radiology practice. However, in his seminal work, Christiansen characterized a new form of technologic innovation, known as "disruptive technology," whose emergence often heralds the replacement of market leaders in an industry by competitors who are quicker in adopting and deploying the new technology. This article briefly describes the phenomenon of disruptive technology and addresses the challenges that organizations face in dealing with disruptive technology. The article raises 4 questions about the future of radiology: (1) Are health care and radiology vulnerable to disruptive technology? (2) What kinds of change may be in store for the radiology profession? (3) Can the radiology profession prepare itself to recognize and respond to a disruptive innovation among a group of new imaging technologies? and (4) How should a radiology organization decide whether to invest significant resources in a potentially disruptive technology? This article addresses these questions by reviewing key insights from leading "gurus" in the fields of competitive strategy and technology management and applying them to radiology. This illustrates how and why (despite past successes) the radiology profession may still have a blind spot in recognizing and handling disruptive technologies.

  14. Altered time course of amygdala activation during speech anticipation in social anxiety disorder.

    Davies, Carolyn D; Young, Katherine; Torre, Jared B; Burklund, Lisa J; Goldin, Philippe R; Brown, Lily A; Niles, Andrea N; Lieberman, Matthew D; Craske, Michelle G

    2017-02-01

    Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Participants (SAD n=58; HC n=16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task. Repeated measures multi-level modeling analyses were used to examine group differences in time course activity during speech vs. control anticipation for regions of interest, including bilateral amygdala, insula, ventral striatum, and dorsal anterior cingulate cortex. The time course of amygdala activity was more prolonged and less variable throughout speech anticipation in SAD participants compared to HCs, whereas the overall magnitude of amygdala response did not differ between groups. Magnitude and time course of activity was largely similar between groups across other regions of interest. Analyses were restricted to regions of interest and task order was the same across participants due to the nature of deception instructions. Sustained amygdala time course during anticipation may uniquely reflect heightened detection of threat or deficits in emotion regulation in socially anxious individuals. Findings highlight the importance of examining temporal dynamics of amygdala responding. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. The relationship between action anticipation and emotion recognition in athletes of open skill sports.

    Shih, Yu-Ling; Lin, Chia-Yen

    2016-08-01

    Action anticipation plays an important role in the successful performance of open skill sports, such as ball and combat sports. Evidence has shown that elite athletes of open sports excel in action anticipation. Most studies have targeted ball sports and agreed that information on body mechanics is one of the key determinants for successful action anticipation in open sports. However, less is known about combat sports, and whether facial emotions have an influence on athletes' action anticipation skill. It has been suggested that the understanding of intention in combat sports relies heavily on emotional context. Based on this suggestion, the present study compared the action anticipation performances of taekwondo athletes, weightlifting athletes, and non-athletes and then correlated these with their performances of emotion recognition. This study primarily found that accurate action anticipation does not necessarily rely on the dynamic information of movement, and that action anticipation performance is correlated with that of emotion recognition in taekwondo athletes, but not in weightlifting athletes. Our results suggest that the recognition of facial emotions plays a role in the action prediction in such combat sports as taekwondo.

  16. Optical mapping of prefrontal brain connectivity and activation during emotion anticipation.

    Wang, Meng-Yun; Lu, Feng-Mei; Hu, Zhishan; Zhang, Juan; Yuan, Zhen

    2018-09-17

    Accumulated neuroimaging evidence shows that the dorsal lateral prefrontal cortex (dlPFC) is activated during emotion anticipation. The aim of this work is to examine the brain connectivity and activation differences in dlPFC between the positive, neutral and negative emotion anticipation by using functional near-infrared spectroscopy (fNIRS). The hemodynamic responses were first assessed for all subjects during the performance of various emotion anticipation tasks. And then small-world analysis was performed, in which the small-world network indicators including the clustering coefficient, average path length, average node degree, and measure of small-world index were calculated for the functional brain networks associated with the positive, neutral and negative emotion anticipation, respectively. We discovered that compared to negative and neutral emotion anticipation, the positive one exhibited enhanced brain activation in the left dlPFC. Although the functional brain networks for the three emotion anticipation cases manifested the small-world properties regarding the clustering coefficient, average path length, average node degree, and measure of small-world index, the positive one showed significantly higher clustering coefficient and shorter average path length than those from the neutral and negative cases. Consequently, the small-world network indicators and brain activation in dlPPC were able to distinguish well between the positive, neutral and negative emotion anticipation. Copyright © 2018 Elsevier B.V. All rights reserved.

  17. Anticipation of high arousal aversive and positive movie clips engages common and distinct neural substrates.

    Greenberg, Tsafrir; Carlson, Joshua M; Rubin, Denis; Cha, Jiook; Mujica-Parodi, Lilianne

    2015-04-01

    The neural correlates of anxious anticipation have been primarily studied with aversive and neutral stimuli. In this study, we examined the effect of valence on anticipation by using high arousal aversive and positive stimuli and a condition of uncertainty (i.e. either positive or aversive). The task consisted of predetermined cues warning participants of upcoming aversive, positive, 'uncertain' (either aversive or positive) and neutral movie clips. Anticipation of all affective clips engaged common regions including the anterior insula, dorsal anterior cingulate cortex, thalamus, caudate, inferior parietal and prefrontal cortex that are associated with emotional experience, sustained attention and appraisal. In contrast, the nucleus accumbens and medial prefrontal cortex, regions implicated in reward processing, were selectively engaged during anticipation of positive clips (depicting sexually explicit content) and the mid-insula, which has been linked to processing aversive stimuli, was selectively engaged during anticipation of aversive clips (depicting graphic medical procedures); these three areas were also activated during anticipation of 'uncertain' clips reflecting a broad preparatory response for both aversive and positive stimuli. These results suggest that a common circuitry is recruited in anticipation of affective clips regardless of valence, with additional areas preferentially engaged depending on whether expected stimuli are negative or positive. © The Author (2014). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  18. How Anticipated and Experienced Stigma Can Contribute to Self-Stigma: The Case of Problem Gambling.

    Hing, Nerilee; Russell, Alex M T

    2017-01-01

    The degree to which anticipated and experienced public stigma contribute to self-stigma remains open to debate, and little research has been conducted into the self-stigma of problem gambling. This study aimed to examine which aspects of anticipated and experienced stigma (if any) predict the anticipated level of public stigma associated with problem gambling and the degree of self-stigma felt by people experiencing problem gambling. An online survey of 177 Australians experiencing problem gambling examined whether aspects of the public characterization of problem gambling, anticipated reactions to problem gamblers, and experiences of devaluation and discrimination predicted anticipated level of public stigma and self-stigma. The study found that self-stigma increases with expectations that the public applies a range of negative stereotypes to people with gambling problems, holds demeaning and discriminatory attitudes toward them, and considers them to lead highly disrupted lives. These variables directly predicted anticipated level of public stigma and indirectly predicted self-stigma. These findings lend weight to conceptualizations of self-stigma as an internalization of actual or anticipated public stigma. They also highlight the need for stigma reduction efforts, particularly those that lower negative stereotyping and prejudicial attitudes, to improve currently low rates of help-seeking amongst people with gambling problems.

  19. Regulatory Mode and Risk-Taking: The Mediating Role of Anticipated Regret.

    Panno, Angelo; Lauriola, Marco; Pierro, Antonio

    2015-01-01

    We propose that decision maker's regulatory mode affects risk-taking through anticipated regret. In the Study 1 either a locomotion or an assessment orientation were experimentally induced, and in the Studies 2 and 3 these different orientations were assessed as chronic individual differences. To assess risk-taking we used two behavioral measures of risk: BART and hot-CCT. The results show that experimentally induced assessment orientation--compared to locomotion--leads to decreased risk-taking through increased anticipated regret (Study 1). People chronically predisposed to be in the assessment state take less risk through increased anticipated regret (Study 2 and Study 3). Study 2 results also show a marginally non-significant indirect effect of chronic locomotion mode on BART through anticipated regret. Differently, Study 3 shows that people chronically predisposed to be in the locomotion state take greater risk through decreased anticipated regret, when play a dynamic risk task triggering stronger emotional arousal. Through all three studies, the average effect size for the relationship of assessment with anticipated regret was in the moderate-large range, whereas for risk-taking was in the moderate range. The average effect size for the relationship of locomotion with anticipated regret was in the moderate range, whereas for risk-taking was in the small-moderate range. These results increase our understanding of human behavior under conditions of risk obtaining novel insights into regulatory mode theory and decision science.

  20. Ascertainment bias causes false signal of anticipation in genetic prion disease.

    Minikel, Eric Vallabh; Zerr, Inga; Collins, Steven J; Ponto, Claudia; Boyd, Alison; Klug, Genevieve; Karch, André; Kenny, Joanna; Collinge, John; Takada, Leonel T; Forner, Sven; Fong, Jamie C; Mead, Simon; Geschwind, Michael D

    2014-10-02

    Anticipation is the phenomenon whereby age of onset in genetic disease decreases in successive generations. Three independent reports have claimed anticipation in Creutzfeldt-Jakob disease (CJD) caused by the c.598G > A mutation in PRNP encoding a p.Glu200Lys (E200K) substitution in the prion protein. If confirmed, this finding would carry clear implications for genetic counseling. We analyzed pedigrees with this mutation from four prion centers worldwide (n = 217 individuals with the mutation) to analyze age of onset and death in affected and censored individuals. We show through simulation that selective ascertainment of individuals whose onset falls within the historical window since the mutation's 1989 discovery is sufficient to create robust false signals both of anticipation and of heritability of age of onset. In our data set, the number of years of anticipation observed depends upon how strictly the data are limited by the ascertainment window. Among individuals whose disease was directly observed at a study center, a 28-year difference between parent and child age of onset is observed (p = 0.002), but including individuals ascertained retrospectively through family history reduces this figure to 7 years (p = 0.005). Applying survival analysis to the most thoroughly ascertained subset of data eliminates the signal of anticipation. Moreover, even non-CJD deaths exhibit 16 years anticipation (p = 0.002), indicating that ascertainment bias can entirely explain observed anticipation. We suggest that reports of anticipation in genetic prion disease are driven entirely by ascertainment bias. Guidelines for future studies claiming statistical evidence for anticipation are suggested. Copyright © 2014 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

  1. Anticipation of smoking sufficiently dampens stress reactivity in nicotine-deprived smokers.

    Bradford, Daniel E; Curtin, John J; Piper, Megan E

    2015-02-01

    Most smokers attempting to quit will relapse, even when using evidence-based cessation treatment. This illustrates the need for better understanding of the relapse process to thereby improve cessation treatments. Although the impact of stress sensitivity on relapse is clear, little research has precisely examined stress reactivity in addicted individuals. Further, most research on relapse focuses on affect surrounding self-administration, and does not address potentially important preconsumption processes such as anticipation of use. We examined the effects of anticipation and actual smoking on stress reactivity in 34 deprived smokers withdrawn for 24 hr and 37 nondeprived smokers, with 37 nonsmoker controls. Using a cued shock stressor task, we measured stress reactivity via startle potentiation and self-reported anxiety. After completing the task once, smokers anticipated smoking a cigarette resting in front of them while they completed the task a second time. Smokers then smoked before completing the task a third and final time. Nonsmokers anticipated and drank water as a control. Anticipation of smoking significantly attenuated both startle potentiation and self-reported anxiety to shock cues for deprived smokers relative to nondeprived smokers. Smokers' stress reactivity was not reduced by smoking beyond the prior effect of anticipation. These results suggest that anticipation, rather than actual drug consumption, may drive the primary reinforcing effect of reduced stress reactivity in smoking. Future research is needed to understand this effect of anticipation on drug use and to determine whether anticipation would make an effective intervention target for addiction and other psychopathology that exhibits increased stress sensitivity. (PsycINFO Database Record (c) 2015 APA, all rights reserved).

  2. Overcoming artefact: anticipation in 284 Portuguese kindreds with familial amyloid polyneuropathy (FAP) ATTRV30M.

    Lemos, Carolina; Coelho, Teresa; Alves-Ferreira, Miguel; Martins-da-Silva, Ana; Sequeiros, Jorge; Mendonça, Denisa; Sousa, Alda

    2014-03-01

    Early-onset (≤40 years) and later-onset (≥50 years) cases of familial amyloid polyneuropathy (FAP) ATTRV30M are not different entities, often coexisting in the same family, and showing anticipation (earlier age-at-onset (AO) in younger generations, usually associated with more severe phenotype). Historically, anticipation has been ascribed to ascertainment biases. Our aim was to study anticipation in a very large number of FAP kindreds, removing possible biases, and gain further insight into parent-of-origin effects. We analysed 926 parent-offspring pairs (from the Unidade Clínica de Paramiloidose roster, collected in 70 years), both clinically observed and had well-established AO, correcting for intrafamilial correlations. Women had a significantly higher AO, either for daughters (mean: 33.70, SD: 6.84) vs sons (29.43, 6.08); or mothers (39.57, 11.75) vs. fathers (35.62, 11.62). Also, 291 pairs showed marked anticipation (≥10 years); the transmitting parent was the mother in 203 pairs. Mother-son pairs showed larger anticipation (10.43, 9.34), while father-daughter pairs showed only a residual anticipation (1.23, 9.77). Gender of offspring and parents was highly significant (with no interaction). To remove possible biases, we repeated analyses: (1) excluding the proband; (2) removing pairs with simultaneous onset; and (3) excluding offspring born after 1960. Anticipation was found in all subsamples, with the same trend for a parent-of-origin effect. Noteworthy, parents with AO ≤40 years never had offspring with AO ≥50. These findings confirm anticipation as a true biological phenomenon, also in FAP ATTRV30M. Acknowledgment of anticipation may have important clinical implications in genetic counselling of offspring and in follow-up of mutation carriers.

  3. Effect of familiarity on reward anticipation in children with and without autism spectrum disorders.

    Katherine K M Stavropoulos

    Full Text Available Previous research on the reward system in autism spectrum disorders (ASD suggests that children with ASD anticipate and process social rewards differently than typically developing (TD children--but has focused on the reward value of unfamiliar face stimuli. Children with ASD process faces differently than their TD peers. Previous research has focused on face processing of unfamiliar faces, but less is known about how children with ASD process familiar faces. The current study investigated how children with ASD anticipate rewards accompanied by familiar versus unfamiliar faces.The stimulus preceding negativity (SPN of the event-related potential (ERP was utilized to measure reward anticipation. Participants were 6- to 10-year-olds with (N = 14 and without (N = 14 ASD. Children were presented with rewards accompanied by incidental face or non-face stimuli that were either familiar (caregivers or unfamiliar. All non-face stimuli were composed of scrambled face elements in the shape of arrows, controlling for visual properties.No significant differences between familiar versus unfamiliar faces were found for either group. When collapsing across familiarity, TD children showed larger reward anticipation to face versus non-face stimuli, whereas children with ASD did not show differential responses to these stimulus types. Magnitude of reward anticipation to faces was significantly correlated with behavioral measures of social impairment in the ASD group.The findings do not provide evidence for differential reward anticipation for familiar versus unfamiliar face stimuli in children with or without ASD. These findings replicate previous work suggesting that TD children anticipate rewards accompanied by social stimuli more than rewards accompanied by non-social stimuli. The results do not support the idea that familiarity normalizes reward anticipation in children with ASD. Our findings also suggest that magnitude of reward anticipation to faces is

  4. Formaldehyde in the Galactic Centre

    Cohen, R.J.; Few, R.W.

    1981-01-01

    Formaldehyde 6-cm absorption in the direction of the Galactic Centre has been surveyed using the Jodrell Bank MK II radio telescope (beam-width 10 x 9 arcmin). The observations sample the region - 2 0 = 0 and - 0 0 .5 = 0 .5, with a velocity range of 620 km s -1 , a velocity resolution of 2.1 km s -1 and an rms noise level of approximately 0.03 K. The data are presented as contour maps showing line temperature as a function of latitude and velocity (b-V maps) and as a function of longitude and velocity (l-V maps). Similar maps of the line-to-continuum ratio are also presented. The radial distribution of formaldehyde (H 2 CO) in the Galactic Centre region is derived using two different kinematic models which give similar results. Formaldehyde is strongly concentrated in the Galactic Centre in a layer of latitude extent approximately 0 0 .5 and longitude extent approximately 4 0 which contains one quarter of all the H 2 CO in the Galaxy. The distribution is centred on l approximately 1 0 . The individual H 2 CO features are described in detail. (author)

  5. The DEMETER Science Mission Centre

    Lagoutte, D.; Brochot, J.; Y.; de Carvalho, D.; Elie, F.; Harivelo, F.; Hobara, Y.; Madrias, L.; Parrot, M.; Pincon, J. L.; Berthelier, J. J.; Peschard, D.; Seran, E.; Gangloff, M.; Sauvaud, J. A.; Lebreton, J. P.; Štverák, Štěpán; Trávníček, Pavel M.; Grygorczuk, J.; Slominski, J.; Wronowski, R.; Barbier, S.; Bernard, P.; Gaboriaud, A.; Wallut, J. M.

    2006-01-01

    Roč. 54, č. 5 (2006), s. 428-440 ISSN 0032-0633 Institutional research plan: CEZ:AV0Z30420517 Keywords : Mission Centre * Data processing Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics Impact factor: 1.509, year: 2006

  6. CENTRE OF THE MAIN INTERESTS

    DIANA DELEANU

    2013-05-01

    Full Text Available The centre of the main interests of the debtor is a legal tool meant to settle conflicts that can arise between jurisdictions in cross-border insolvencies, based on the principles of mutual recognition and co-operation.

  7. Shale Gas Development and Brook Trout: Scaling Best Management Practices to Anticipate Cumulative Effects

    Smith, David; Snyder, Craig D.; Hitt, Nathaniel P.; Young, John A.; Faulkner, Stephen P.

    2012-01-01

    Shale gas development may involve trade-offs between energy development and benefits provided by natural ecosystems. However, current best management practices (BMPs) focus on mitigating localized ecological degradation. We review evidence for cumulative effects of natural gas development on brook trout (Salvelinus fontinalis) and conclude that BMPs should account for potential watershed-scale effects in addition to localized influences. The challenge is to develop BMPs in the face of uncertainty in the predicted response of brook trout to landscape-scale disturbance caused by gas extraction. We propose a decision-analysis approach to formulating BMPs in the specific case of relatively undisturbed watersheds where there is consensus to maintain brook trout populations during gas development. The decision analysis was informed by existing empirical models that describe brook trout occupancy responses to landscape disturbance and set bounds on the uncertainty in the predicted responses to shale gas development. The decision analysis showed that a high efficiency of gas development (e.g., 1 well pad per square mile and 7 acres per pad) was critical to achieving a win-win solution characterized by maintaining brook trout and maximizing extraction of available gas. This finding was invariant to uncertainty in predicted response of brook trout to watershed-level disturbance. However, as the efficiency of gas development decreased, the optimal BMP depended on the predicted response, and there was considerable potential value in discriminating among predictive models through adaptive management or research. The proposed decision-analysis framework provides an opportunity to anticipate the cumulative effects of shale gas development, account for uncertainty, and inform management decisions at the appropriate spatial scales.

  8. Anticipating and addressing event-specific alcohol consumption among adolescents

    Simone Pettigrew

    2016-07-01

    Full Text Available Abstract Background Various specific events and celebrations are associated with excessive alcohol consumption and related harms. End-of-school celebrations such as Schoolies in Australia are of particular concern given high levels of documented harm among underage and young drinkers. The present study investigated high school students’ expectations of their Schoolies celebrations to inform future interventions to reduce adverse outcomes among members of this vulnerable group and other young people involved in similar rites of passage. Methods A link to an online survey was distributed via high schools and Schoolies-related websites. The survey included qualitative questions that invited respondents to discuss (i aspects of Schoolies they were looking forward to most and least and (ii their perceptions of the likely consequences if they refrained from consuming alcohol during the event. In total, 435 students provided responses. Results Respondents discussed the role of Schoolies in marking their transition to adulthood. Their comments revealed a cross-temporal focus indicating that Schoolies is simultaneously symbolic of the past, present, and future. Through its ability to enhance social interaction, alcohol was perceived to have a vital role in realising the potential of this event to signify and facilitate this temporal progression. Conclusions Results suggest interventions that treat Schoolies as an isolated event that occurs in specific locations may fail to appreciate the extent to which these events transcend time for those involved. Instead, harm reduction is likely to involve a reconceptualisation of the event among both participants and authority figures to facilitate the provision of alternative pastimes to drinking during Schoolies that yield similar social benefits.

  9. Anticipating and addressing event-specific alcohol consumption among adolescents.

    Pettigrew, Simone; Biagioni, Nicole; Jongenelis, Michelle I

    2016-07-29

    Various specific events and celebrations are associated with excessive alcohol consumption and related harms. End-of-school celebrations such as Schoolies in Australia are of particular concern given high levels of documented harm among underage and young drinkers. The present study investigated high school students' expectations of their Schoolies celebrations to inform future interventions to reduce adverse outcomes among members of this vulnerable group and other young people involved in similar rites of passage. A link to an online survey was distributed via high schools and Schoolies-related websites. The survey included qualitative questions that invited respondents to discuss (i) aspects of Schoolies they were looking forward to most and least and (ii) their perceptions of the likely consequences if they refrained from consuming alcohol during the event. In total, 435 students provided responses. Respondents discussed the role of Schoolies in marking their transition to adulthood. Their comments revealed a cross-temporal focus indicating that Schoolies is simultaneously symbolic of the past, present, and future. Through its ability to enhance social interaction, alcohol was perceived to have a vital role in realising the potential of this event to signify and facilitate this temporal progression. Results suggest interventions that treat Schoolies as an isolated event that occurs in specific locations may fail to appreciate the extent to which these events transcend time for those involved. Instead, harm reduction is likely to involve a reconceptualisation of the event among both participants and authority figures to facilitate the provision of alternative pastimes to drinking during Schoolies that yield similar social benefits.

  10. Antibiotics in Canadian poultry productions and anticipated alternatives

    Moussa Sory Diarra

    2014-06-01

    Full Text Available The use of antibiotics in food-producing animals has significantly increased animal health by lowering mortality and the incidence of diseases. Antibiotics also have largely contributed to increase productivity of farms. However, antibiotic usage in general and relevance of non-therapeutic antibiotics in feed (growth promoters need to be reevaluated especially because bacterial pathogens of humans and animals have developed and shared a variety of antibiotic resistance mechanisms that can easily spread within microbial communities. In Canada, poultry production involves more than 2,600 regulated chicken producers. There are several antibiotics approved as feed additives available for poultry farmers. Feed recipes and mixtures greatly vary geographically and from one farm to another, making links between use of a specific antibiotic feed additive and production yields or selection of specific antibiotic-resistant bacteria difficult to establish. Many on-farm studies have revealed the widespread presence of antibiotic-resistant bacteria in broiler chickens. While sporadic reports linked the presence of antibiotic-resistant organisms to the use of feed supplemented with antibiotics, no recent studies could clearly demonstrate the benefit of antimicrobial growth promoters on performance and production yields. With modern biosecurity and hygienic practices, there is a genuine concern that intensive utilization of antibiotics or use of antimicrobial growth promoters in feed might no longer be useful. Public pressure and concerns about food and environmental safety (antibiotic residues, antibiotic-resistant pathogens have driven researchers to actively look for alternatives to antibiotics. Some of the alternatives include pre- and probiotics, organic acids and essential oils. We will describe here the properties of some bioactive molecules, like those found in cranberry, which have shown interesting polyvalent antibacterial and immuno

  11. Density waves in a lattice hydrodynamic traffic flow model with the anticipation effect

    Zhao Min; Sun Di-Hua; Tian Chuan

    2012-01-01

    By introducing the traffic anticipation effect in the real world into the original lattice hydrodynamic model, we present a new anticipation effect lattice hydrodynamic (AELH) model, and obtain the linear stability condition of the model by applying the linear stability theory. Through nonlinear analysis, we derive the Burgers equation and Korteweg-de Vries (KdV) equation, to describe the propagating behaviour of traffic density waves in the stable and the metastable regions, respectively. The good agreement between simulation results and analytical results shows that the stability of traffic flow can be enhanced when the anticipation effect is considered. (interdisciplinary physics and related areas of science and technology)

  12. A new lattice hydrodynamic traffic flow model with a consideration of multi-anticipation effect

    Tian Chuan; Sun Di-Hua; Yang Shu-Hong

    2011-01-01

    We present a new multi-anticipation lattice hydrodynamic model based on the traffic anticipation effect in the real world. Applying the linear stability theory, we obtain the linear stability condition of the model. Through nonlinear analysis, we derive the modified Korteweg-de Vries equation to describe the propagating behaviour of a traffic density wave near the critical point. The good agreement between the simulation results and the analytical results shows that the stability of traffic flow can be enhanced when the multi-anticipation effect is considered. (interdisciplinary physics and related areas of science and technology)

  13. Organisational culture and post-merger integration in an academic health centre: a mixed-methods study.

    Ovseiko, Pavel V; Melham, Karen; Fowler, Jan; Buchan, Alastair M

    2015-01-22

    Around the world, the last two decades have been characterised by an increase in the numbers of mergers between healthcare providers, including some of the most prestigious university hospitals and academic health centres. However, many mergers fail to bring the anticipated benefits, and successful post-merger integration in university hospitals and academic health centres is even harder to achieve. An increasing body of literature suggests that organisational culture affects the success of post-merger integration and academic-clinical collaboration. This paper reports findings from a mixed-methods single-site study to examine 1) the perceptions of organisational culture in academic and clinical enterprises at one National Health Service (NHS) trust, and 2) the major cultural issues for its post-merger integration with another NHS trust and strategic partnership with a university. From the entire population of 72 clinician-scientists at one of the legacy NHS trusts, 38 (53%) completed a quantitative Competing Values Framework survey and 24 (33%) also provided qualitative responses. The survey was followed up by semi-structured interviews with six clinician-scientists and a group discussion including five senior managers. The cultures of two legacy NHS trusts differed and were primarily distinct from the culture of the academic enterprise. Major cultural issues were related to the relative size, influence, and history of the legacy NHS trusts, and the implications of these for respective identities, clinical services, and finances. Strategic partnership with a university served as an important ameliorating consideration in reaching trust merger. However, some aspects of university entrepreneurial culture are difficult to reconcile with the NHS service delivery model and may create tension. There are challenges in preserving a more desirable culture at one of the legacy NHS trusts, enhancing cultures in both legacy NHS trusts during their post-merger integration, and

  14. [Air humidifier--benefit or risk?].

    Fidler, A H

    1989-12-01

    Indoor air pollution has become an issue of growing importance for the scientific community. A recent publication of a report of the US Environmental Protection Agency (EPA) showed evidence that portable ultrasonic humidifiers may play a significant role as health hazards as far as indoor air pollution with heavy metal particles is concerned. Especially if the manufacturers' guidelines are not followed strictly and the device is operated with tap water, indoor particle concentrations may reach up to 50 times US outdoor standards for toxic particle concentration. This paper highlights potential risks and benefits of various types of humidifiers, both in private and hospital settings, emphasizing that risks of air humidification in certain situations might outweigh anticipated benefits. The health policy implication of these findings should lead to a more critical application of air humidification in the health care environment and in addition to that, promote better information of the customer about safe operation and useful indications of such devices.

  15. Scenario drafting to anticipate future developments in technology assessment

    Retèl Valesca P

    2012-08-01

    Full Text Available Abstract Background Health Technology Assessment (HTA information, and in particular cost-effectiveness data is needed to guide decisions, preferably already in early stages of technological development. However, at that moment there is usually a high degree of uncertainty, because evidence is limited and different development paths are still possible. We developed a multi-parameter framework to assess dynamic aspects of a technology -still in development-, by means of scenario drafting to determine the effects, costs and cost-effectiveness of possible future diffusion patterns. Secondly, we explored the value of this method on the case of the clinical implementation of the 70-gene signature for breast cancer, a gene expression profile for selecting patients who will benefit most from chemotherapy. Methods To incorporate process-uncertainty, ten possible scenarios regarding the introduction of the 70-gene signature were drafted with European experts. Out of 5 most likely scenarios, 3 drivers of diffusion (non-compliance, technical failure, and uptake were quantitatively integrated in a decision-analytical model. For these scenarios, the cost-effectiveness of the 70-gene signature expressed in Incremental Cost-Effectiveness Ratios (ICERs was compared to clinical guidelines, calculated from the past (2005 until the future (2020. Results In 2005 the ICER was €1,9 million/quality-adjusted-life-year (QALY, meaning that the 70-gene signature was not yet cost-effective compared to the current clinical guideline. The ICER for the 70-gene signature improved over time with a range of €1,9 million to €26,145 in 2010 and €1,9 million to €11,123/QALY in 2020 depending on the separate scenario used. From 2010, the 70-gene signature should be cost-effective, based on the combined scenario. The uptake-scenario had strongest influence on the cost-effectiveness. Conclusions When optimal diffusion of a technology is sought, incorporating process

  16. The CCCB is a cultural centre, not a tourist centre

    Elena Xirau

    2004-04-01

    Full Text Available Last February, Barcelona's Centre of Contemporary Culture (CCCB celebrated its first ten years in existence. During this time, this institution has looked to be a showcase to the most modern and innovative cultural expressions focused on reflecting on the concept of the city. In this interview, Josep Ramoneda offers his personal view, as the CCCB's director. He talks of how this cultural project was born, of how the concept of the institution took shape in the CCCB, of its relations with Barcelona's Strategic Plan, of how the project has evolved, of the architectural remodelling of the Casa de la Caritat building for its conversion into a cultural centre, of the relations with other institutions and its future.

  17. Gestion du Centre | CRDI - Centre de recherches pour le ...

    Le Comité de gestion du Centre (CGC) est composé des membres de la haute direction du CRDI, notamment les directeurs de nos quatre bureaux régionaux et de nos principaux secteurs de programme. Le CGC travaille en collaboration avec le président afin de soutenir la recherche pour le développement, lui fournissant ...

  18. Protecting against natural hazards - Information seeking behaviour in anticipation of severe weather events

    Jeuring, Jelmer

    2011-01-01

    Protection against natural hazards - Information seeking behaviour in anticipation of severe weather events Severe weather events can have considerable impact on society, including tourism organisations and tourists. Providing accurate and timely information about possible risks due to environmental

  19. Predicting dynamic behavior via anticipating synchronization in coupled pendulum-like systems

    Xu Shiyun; Yang Ying

    2009-01-01

    In this paper, the regime of anticipating synchronization (sometimes called predicted synchronization) in a class of nonlinear dynamical systems is investigated by testing the global asymptotical stability of time-delayed error dynamics. Sufficient conditions in terms of linear matrix inequalities are established for anticipating synchronization between such systems with and without state time delay. These results allow one to predict the dynamic behavior of the systems by using a copy of the same system that performs as a slave. Moreover, the cascaded anticipating synchronization is concerned such that several slave systems could anticipate the same master system with different delays. Concrete applications to phase-locked loops demonstrate the applicability and validity of the proposed results.

  20. A review of statistical methods for testing genetic anticipation: looking for an answer in Lynch syndrome

    Boonstra, Philip S; Gruber, Stephen B; Raymond, Victoria M

    2010-01-01

    Anticipation, manifested through decreasing age of onset or increased severity in successive generations, has been noted in several genetic diseases. Statistical methods for genetic anticipation range from a simple use of the paired t-test for age of onset restricted to affected parent-child pairs......, and this right truncation effect is more pronounced in children than in parents. In this study, we first review different statistical methods for testing genetic anticipation in affected parent-child pairs that address the issue of bias due to right truncation. Using affected parent-child pair data, we compare...... the issue of multiplex ascertainment and its effect on the different methods. We then focus on exploring genetic anticipation in Lynch syndrome and analyze new data on the age of onset in affected parent-child pairs from families seen at the University of Michigan Cancer Genetics clinic with a mutation...

  1. Perturbation and Stability Analysis of the Multi-Anticipative Intelligent Driver Model

    Chen, Xi-Qun; Xie, Wei-Jun; Shi, Jing; Shi, Qi-Xin

    This paper discusses three kinds of IDM car-following models that consider both the multi-anticipative behaviors and the reaction delays of drivers. Here, the multi-anticipation comes from two ways: (1) the driver is capable of evaluating the dynamics of several preceding vehicles, and (2) the autonomous vehicles can obtain the velocity and distance information of several preceding vehicles via inter-vehicle communications. In this paper, we study the stability of homogeneous traffic flow. The linear stability analysis indicates that the stable region will generally be enlarged by the multi-anticipative behaviors and reduced by the reaction delays. The temporal amplification and the spatial divergence of velocities for local perturbation are also studied, where the results further prove this conclusion. Simulation results also show that the multi-anticipative behaviors near the bottleneck will lead to a quicker backwards propagation of oscillations.

  2. How Stakeholder Sensing and Anticipations Shape the Firm’s Strategic Response Capability

    Hallin, Carina Antonia; Andersen, Torben Juul; Ooi, Can-Seng

    We outline a strategic response capability framework drawing on cognitive neuroscience to explain stakeholder sensing and anticipations as essential input to environmental analysis. Stakeholders receive stimuli from ongoing interactions with the firm and thereby sense current environmental changes...

  3. RTEMS CENTRE- Support and Maintenance CENTRE to RTEMS Operating System

    Silva, H.; Constantino, A.; Coutunho, M.; Freitas, D.; Faustino, S.; Mota, M.; Colaço, P.; Zulianello, M.

    2008-08-01

    RTEMS stands for Real-Time Operating System for Multiprocessor Systems. It is a full featured Real Time Operating System that supports a variety of open APIs and interface standards. It provides a high performance environment for embedded applications, including a fixed-priority preemptive/non-preemptive scheduler, a comprehensive set of multitasking operations and a large range of supported architectures. Support and maintenance CENTRE to RTEMS operating system (RTEMS CENTRE) is a joint initiative of ESA-Portugal Task force, aiming to build a strong technical competence in the space flight (on- board) software, to offer support, maintenance and improvements to RTEMS. This paper provides a high level description of the current and future activities of the RTEMS CENTRE. It presents a brief description of the RTEMS operating system, a description of the tools developed and distributed to the community [1] and the improvements to be made to the operating system, including facilitation for the qualification of RTEMS (4.8.0) [2] for the space missions.

  4. The Mediating Role of Anticipated Guilt in Consumers’ Ethical Decision-Making

    S. STEENHAUT; P. VAN KENHOVE

    2006-01-01

    In this paper we theorize that the anticipation of guilt plays an important role in ethically questionable consumer situations. We propose an ethical decision-making framework incorporating anticipated guilt as partial mediator between consumers’ ethical beliefs (anteceded by ethical ideology) and intentions. In a first study we compared several models using structural equation modeling and found empirical support for our research model. A second experiment was set up to illustrate how retail...

  5. The Roles of Anticipated Guilt, Neutralisation and Advertising Appeals in Consumers' Ethical Decision-Making

    YANG, SHU-TING

    2008-01-01

    In this study, first, the discrepancy between consumers'ethical belief and ethical intention was reported in the ethical context of whether to use plastic carrier bags in supermarkets. Second, the anticipated guilt and consumers'acceptance of neutralization techniques were found to play the important roles in ethical consumers'decision making process. A framework, based on the theory of planned behavior, incorporated anticipated guilt as a mediator between consumers' neutralization and ethic...

  6. The Role of Medial Frontal Cortex in Action Anticipation in Professional Badminton Players.

    Xu, Huan; Wang, Pin; Ye, Zhuo'er; Di, Xin; Xu, Guiping; Mo, Lei; Lin, Huiyan; Rao, Hengyi; Jin, Hua

    2016-01-01

    Some studies show that the medial frontal cortex is associated with more skilled action anticipation, while similar findings are not observed in some other studies, possibly due to the stimuli employed and the participants used as the control group. In addition, no studies have investigated whether there is any functional connectivity between the medial frontal cortex and other brain regions in more skilled action anticipation. Therefore, the present study aimed to re-investigate how the medial frontal cortex is involved in more skilled action anticipation by circumventing the limitations of previous research and to investigate that the medial frontal cortex functionally connected with other brain regions involved in action processing in more skilled action anticipation. To this end, professional badminton players and novices were asked to anticipate the landing position of the shuttlecock while watching badminton match videos or to judge the gender of the players in the matches. The video clips ended right at the point that the shuttlecock and the racket came into contact to reduce the effect of information about the trajectory of the shuttlecock. Novices who lacked training and watching experience were recruited for the control group to reduce the effect of sport-related experience on the medial frontal cortex. Blood oxygenation level-dependent activation was assessed by means of functional magnetic resonance imaging. Compared to novices, badminton players exhibited stronger activation in the left medial frontal cortex during action anticipation and greater functional connectivity between left medial frontal cortex and some other brain regions (e.g., right posterior cingulate cortex). Therefore, the present study supports the position that the medial frontal cortex plays a role in more skilled action anticipation and that there is a specific brain network for more skilled action anticipation that involves right posterior cingulate cortex, right fusiform gyrus

  7. Circadian Clocks for All Meal-Times: Anticipation of 2 Daily Meals in Rats

    Mistlberger, Ralph E.; Kent, Brianne A.; Chan, Sofina; Patton, Danica F.; Weinberg, Alexander; Parfyonov, Maksim

    2012-01-01

    Anticipation of a daily meal in rats has been conceptualized as a rest-activity rhythm driven by a food-entrained circadian oscillator separate from the pacemaker generating light-dark (LD) entrained rhythms. Rats can also anticipate two daily mealtimes, but whether this involves independently entrained oscillators, one ‘continuously consulted’ clock, cue-dependent non-circadian interval timing or a combination of processes, is unclear. Rats received two daily meals, beginning 3-h (meal 1) and 13-h (meal 2) after lights-on (LD 14∶10). Anticipatory wheel running began 68±8 min prior to meal 1 and 101±9 min prior to meal 2 but neither the duration nor the variability of anticipation bout lengths exhibited the scalar property, a hallmark of interval timing. Meal omission tests in LD and constant dark (DD) did not alter the timing of either bout of anticipation, and anticipation of meal 2 was not altered by a 3-h advance of meal 1. Food anticipatory running in this 2-meal protocol thus does not exhibit properties of interval timing despite the availability of external time cues in LD. Across all days, the two bouts of anticipation were uncorrelated, a result more consistent with two independently entrained oscillators than a single consulted clock. Similar results were obtained for meals scheduled 3-h and 10-h after lights-on, and for a food-bin measure of anticipation. Most rats that showed weak or no anticipation to one or both meals exhibited elevated activity at mealtime during 1 or 2 day food deprivation tests in DD, suggesting covert operation of circadian timing in the absence of anticipatory behavior. A control experiment confirmed that daytime feeding did not shift LD-entrained rhythms, ruling out displaced nocturnal activity as an explanation for daytime activity. The results favor a multiple oscillator basis for 2-meal anticipatory rhythms and provide no evidence for involvement of cue-dependent interval timing. PMID:22355393

  8. Anticipated chaos in a nonsymmetric coupled external-cavity-laser system

    Rees, Paul; Spencer, Paul S.; Pierce, Iestyn; Sivaprakasam, S.; Shore, K. Alan

    2003-01-01

    We explain how the anticipation of chaos in a coupled external cavity laser system described by Sivaprakasam, Shahverdiev, Spencer, and Shore [Phys. Rev. Lett. 87, 154101 (2001)] is obtained. We show that the external cavity induces the required symmetry breaking necessary for the existence of a time delay between the synchronized output of the two laser diodes. The inclusion of a detuning between the two lasers causes one laser to anticipate the chaotic dynamics of the other

  9. Coexistence and switching of anticipating synchronization and lag synchronization in an optical system

    Wu, Liang; Zhu, Shiqun

    2003-01-01

    The chaotic synchronization between two bi-directionally coupled external cavity single-mode semiconductor lasers is investigated. Numerical simulation shows that anticipating synchronization and lag synchronization coexist and switch between each other in certain parameter regime. The anticipating time with different effects that were discussed quite differently in the previous theoretical analysis and experimental observation is determined by the involved parameters in the system

  10. ATWS analyses. Analysis of anticipated transients without reactor scram in Combustion Engineering NSSS's

    1976-05-01

    Results are presented of analyses of the transient thermal-hydraulic conditions and radiological release consequences which would occur in power plants which employ a Combustion Engineering Nuclear Steam Supply System during Anticipated Transients Without Scram due to a lack of insertion of the Control Element Assemblies upon signals for automatic or manual reactor shutdown. The transients analyzed include all events which meet the criterion to be considered as anticipated at least once in the plant lifetime with automatic reactor shutdown

  11. Anticipation, teamwork and cognitive load: chasing efficiency during robot-assisted surgery.

    Sexton, Kevin; Johnson, Amanda; Gotsch, Amanda; Hussein, Ahmed A; Cavuoto, Lora; Guru, Khurshid A

    2018-02-01

    Robot-assisted surgery (RAS) has changed the traditional operating room (OR), occupying more space with equipment and isolating console surgeons away from the patients and their team. We aimed to evaluate how anticipation of surgical steps and familiarity between team members impacted efficiency. We analysed recordings (video and audio) of 12 robot-assisted radical prostatectomies. Any requests between surgeon and the team members were documented and classified by personnel, equipment type, mode of communication, level of inconvenience in fulfilling the request and anticipation. Surgical team members completed questionnaires assessing team familiarity and cognitive load (National Aeronautics and Space Administration - Task Load Index). Predictors of team efficiency were assessed using Pearson correlation and stepwise linear regression. 1330 requests were documented, of which 413 (31%) were anticipated. Anticipation correlated negatively with operative time, resulting in overall 8% reduction of OR time. Team familiarity negatively correlated with inconveniences. Anticipation ratio, per cent of requests that were non-verbal and total request duration were significantly correlated with the console surgeons' cognitive load (r=0.77, p=0.006; r=0.63, p=0.04; and r=0.70, p=0.02, respectively). Anticipation and active engagement by the surgical team resulted in shorter operative time, and higher familiarity scores were associated with fewer inconveniences. Less anticipation and non-verbal requests were also associated with lower cognitive load for the console surgeon. Training efforts to increase anticipation and team familiarity can improve team efficiency during RAS. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  12. Dietary fat and corticosterone levels are contributing factors to meal anticipation.

    Namvar, Sara; Gyte, Amy; Denn, Mark; Leighton, Brendan; Piggins, Hugh D

    2016-04-15

    Daily restricted access to food leads to the development of food anticipatory activity and metabolism, which depends upon an as yet unidentified food-entrainable oscillator(s). A premeal anticipatory peak in circulating hormones, including corticosterone is also elicited by daily restricted feeding. High-fat feeding is associated with elevated levels of corticosterone with disrupted circadian rhythms and a failure to develop robust meal anticipation. It is not clear whether the disrupted corticosterone rhythm, resulting from high-fat feeding contributes to attenuated meal anticipation in high-fat fed rats. Our aim was to better characterize meal anticipation in rats fed a low- or high-fat diet, and to better understand the role of corticosterone in this process. To this end, we utilized behavioral observations, hypothalamic c-Fos expression, and indirect calorimetry to assess meal entrainment. We also used the glucocorticoid receptor antagonist, RU486, to dissect out the role of corticosterone in meal anticipation in rats given daily access to a meal with different fat content. Restricted access to a low-fat diet led to robust meal anticipation, as well as entrainment of hypothalamic c-Fos expression, metabolism, and circulating corticosterone. These measures were significantly attenuated in response to a high-fat diet, and animals on this diet exhibited a postanticipatory rise in corticosterone. Interestingly, antagonism of glucocorticoid activity using RU486 attenuated meal anticipation in low-fat fed rats, but promoted meal anticipation in high-fat-fed rats. These findings suggest an important role for corticosterone in the regulation of meal anticipation in a manner dependent upon dietary fat content. Copyright © 2016 the American Physiological Society.

  13. A negative relationship between ventral striatal loss anticipation response and impulsivity in borderline personality disorder

    Herbort, Maike C.; Soch, Joram; W?stenberg, Torsten; Krauel, Kerstin; Pujara, Maia; Koenigs, Michael; Gallinat, J?rgen; Walter, Henrik; Roepke, Stefan; Schott, Bj?rn H.

    2016-01-01

    Patients with borderline personality disorder (BPD) frequently exhibit impulsive behavior, and self-reported impulsivity is typically higher in BPD patients when compared to healthy controls. Previous functional neuroimaging studies have suggested a link between impulsivity, the ventral striatal response to reward anticipation, and prediction errors. Here we investigated the striatal neural response to monetary gain and loss anticipation and their relationship with impulsivity in 21 female BP...

  14. The role of medial frontal gyrus in action anticipation in professional badminton players

    Huan Xu

    2016-11-01

    Full Text Available Some studies show that the medial frontal cortex is associated with more skilled action anticipation, while similar findings are not observed in some other studies, possibly due to the stimuli employed and the participants used as the control group. In addition, no studies have investigated whether there is any functional connectivity between the medial frontal cortex and other brain regions in more skilled action anticipation. Therefore, the present study aimed to re-investigate how the medial frontal cortex is involved in more skilled action anticipation by circumventing the limitations of previous research and to investigate that the medial frontal cortex functionally connected with other brain regions involved in action processing in more skilled action anticipation. To this end, professional badminton players and novices were asked to anticipate the landing position of the shuttlecock while watching badminton match videos or to judge the gender of the players in the matches. The video clips ended right at the point that the shuttlecock and the racket came into contact to reduce the effect of information about the trajectory of the shuttlecock. Novices who lacked training and watching experience were recruited for the control group to reduce the effect of sport-related experience on the medial frontal cortex. Blood oxygenation level-dependent (BOLD activation was assessed by means of functional magnetic resonance imaging (fMRI. Compared to novices, badminton players exhibited stronger activation in the left medial frontal cortex during action anticipation and greater functional connectivity between left medial frontal cortex and some other brain regions (e.g., right posterior cingulate cortex. Therefore, the present study supports the position that the medial frontal cortex plays a role in more skilled action anticipation and that there is a specific brain network for more skilled action anticipation that involves right posterior cingulate

  15. Supporting anticipation in driving through attentional and interpretational in-vehicle displays.

    Stahl, Patrick; Donmez, Birsen; Jamieson, Greg A

    2016-06-01

    This paper evaluates two different types of in-vehicle interfaces to support anticipation in driving: one aids attention allocation and the other aids interpretation of traffic in addition to attention allocation. Anticipation is a competency that has been shown to facilitate safety and eco-driving through the efficient positioning of a vehicle for probable, upcoming changes in traffic. This competency has been shown to improve with driving experience. In an earlier simulator study, we showed that compared to novice drivers, experienced drivers exhibited a greater number of timely actions to avoid upcoming traffic conflicts. In this study, we seek to facilitate anticipation in general and for novice drivers in particular, who appear to lack the competency. We hypothesize that anticipation depends on two major steps and that it can be supported by aiding each: (1) conscious perception of relevant cues, and (2) effective processing of these cues to create a situational assessment as a basis for anticipation of future developments. We conducted a simulator experiment with 24 experienced and 24 novice drivers to evaluate two interfaces that were designed to aid the two hypothesized steps of anticipation. The attentional interface was designed to direct attention toward the most relevant cue. The interpretational interface represented several cues, and in addition to directing attention also aimed to aid sense-making of these cues. The results confirmed our hypothesis that novice drivers' anticipation performance, as measured through timely actions to avoid upcoming traffic conflicts, would be improved with either interface type. However, results contradicted our expectation that novice drivers would obtain larger improvements with the interpretational interface. Experienced drivers performed better than novice drivers to begin with and did not show any statistically significant improvements with either interface. Both interfaces improved anticipation performance for

  16. The Role of Medial Frontal Cortex in Action Anticipation in Professional Badminton Players

    Xu, Huan; Wang, Pin; Ye, Zhuo’er; Di, Xin; Xu, Guiping; Mo, Lei; Lin, Huiyan; Rao, Hengyi; Jin, Hua

    2016-01-01

    Some studies show that the medial frontal cortex is associated with more skilled action anticipation, while similar findings are not observed in some other studies, possibly due to the stimuli employed and the participants used as the control group. In addition, no studies have investigated whether there is any functional connectivity between the medial frontal cortex and other brain regions in more skilled action anticipation. Therefore, the present study aimed to re-investigate how the medial frontal cortex is involved in more skilled action anticipation by circumventing the limitations of previous research and to investigate that the medial frontal cortex functionally connected with other brain regions involved in action processing in more skilled action anticipation. To this end, professional badminton players and novices were asked to anticipate the landing position of the shuttlecock while watching badminton match videos or to judge the gender of the players in the matches. The video clips ended right at the point that the shuttlecock and the racket came into contact to reduce the effect of information about the trajectory of the shuttlecock. Novices who lacked training and watching experience were recruited for the control group to reduce the effect of sport-related experience on the medial frontal cortex. Blood oxygenation level-dependent activation was assessed by means of functional magnetic resonance imaging. Compared to novices, badminton players exhibited stronger activation in the left medial frontal cortex during action anticipation and greater functional connectivity between left medial frontal cortex and some other brain regions (e.g., right posterior cingulate cortex). Therefore, the present study supports the position that the medial frontal cortex plays a role in more skilled action anticipation and that there is a specific brain network for more skilled action anticipation that involves right posterior cingulate cortex, right fusiform gyrus

  17. Pakistan’s national Centre of Excellence contributes to sustaining nuclear security

    Dixit, Aabha

    2016-01-01

    Pakistani front line officers and first responders are in a better position to fight illicit trafficking in nuclear and other radioactive materials, as well as to use advanced radiation detection and monitoring equipment, thanks to training they have received at the country’s Centre of Excellence for Nuclear Security. This is just one of the benefits the country has reaped from the Centre, which is collaborating with the growing International Network for Nuclear Security Training and Support Centres (NSSC Network), building national capacity through training and strengthening technical and scientific support programmes. Since the establishment of the Centre of Excellence, Pakistan has organized training courses on nuclear security for personnel from national and regional organizations. The Centre of Excellence also offers technical support to personnel involved in the maintenance and upgrade of facilities, with a focus on enhancing technical and scientific skills and quality control of equipment.

  18. Interaction systems design and the protocol- and middleware-centred paradigms in distributed application development

    Andrade Almeida, João; van Sinderen, Marten J.; Quartel, Dick; Ferreira Pires, Luis

    2003-01-01

    This paper aims at demonstrating the benefits and importance of interaction systems design in the development of distributed applications. We position interaction systems design with respect to two paradigms that have influenced the design of distributed applications: the middleware-centred and the protocol-centred paradigm. We argue that interaction systems that support application-level interactions should be explicitly designed, using the externally observable behaviour of the interaction ...

  19. A magnetoencephalography study of multi-modal processing of pain anticipation in primary sensory cortices.

    Gopalakrishnan, R; Burgess, R C; Plow, E B; Floden, D P; Machado, A G

    2015-09-24

    Pain anticipation plays a critical role in pain chronification and results in disability due to pain avoidance. It is important to understand how different sensory modalities (auditory, visual or tactile) may influence pain anticipation as different strategies could be applied to mitigate anticipatory phenomena and chronification. In this study, using a countdown paradigm, we evaluated with magnetoencephalography the neural networks associated with pain anticipation elicited by different sensory modalities in normal volunteers. When encountered with well-established cues that signaled pain, visual and somatosensory cortices engaged the pain neuromatrix areas early during the countdown process, whereas the auditory cortex displayed delayed processing. In addition, during pain anticipation, the visual cortex displayed independent processing capabilities after learning the contextual meaning of cues from associative and limbic areas. Interestingly, cross-modal activation was also evident and strong when visual and tactile cues signaled upcoming pain. Dorsolateral prefrontal cortex and mid-cingulate cortex showed significant activity during pain anticipation regardless of modality. Our results show pain anticipation is processed with great time efficiency by a highly specialized and hierarchical network. The highest degree of higher-order processing is modulated by context (pain) rather than content (modality) and rests within the associative limbic regions, corroborating their intrinsic role in chronification. Copyright © 2015 IBRO. Published by Elsevier Ltd. All rights reserved.

  20. Neural correlates of anticipation and processing of performance feedback in social anxiety.

    Heitmann, Carina Y; Peterburs, Jutta; Mothes-Lasch, Martin; Hallfarth, Marlit C; Böhme, Stephanie; Miltner, Wolfgang H R; Straube, Thomas

    2014-12-01

    Fear of negative evaluation, such as negative social performance feedback, is the core symptom of social anxiety. The present study investigated the neural correlates of anticipation and perception of social performance feedback in social anxiety. High (HSA) and low (LSA) socially anxious individuals were asked to give a speech on a personally relevant topic and received standardized but appropriate expert performance feedback in a succeeding experimental session in which neural activity was measured during anticipation and presentation of negative and positive performance feedback concerning the speech performance, or a neutral feedback-unrelated control condition. HSA compared to LSA subjects reported greater anxiety during anticipation of negative feedback. Functional magnetic resonance imaging results showed deactivation of medial prefrontal brain areas during anticipation of negative feedback relative to the control and the positive condition, and medial prefrontal and insular hyperactivation during presentation of negative as well as positive feedback in HSA compared to LSA subjects. The results indicate distinct processes underlying feedback processing during anticipation and presentation of feedback in HSA as compared to LSA individuals. In line with the role of the medial prefrontal cortex in self-referential information processing and the insula in interoception, social anxiety seems to be associated with lower self-monitoring during feedback anticipation, and an increased self-focus and interoception during feedback presentation, regardless of feedback valence. © 2014 Wiley Periodicals, Inc.

  1. Reward and loss anticipation in panic disorder: An fMRI study.

    Held-Poschardt, Dada; Sterzer, Philipp; Schlagenhauf, Florian; Pehrs, Corinna; Wittmann, Andre; Stoy, Meline; Hägele, Claudia; Knutson, Brian; Heinz, Andreas; Ströhle, Andreas

    2018-01-30

    Anticipatory anxiety and harm avoidance are essential features of panic disorder (PD) and may involve deficits in the reward system of the brain, in particular in the ventral striatum. While neuroimaging studies on PD have focused on fearful and negative affective stimulus processing, no investigations have directly addressed deficits in reward and loss anticipation. To determine whether the ventral striatum shows abnormal neural activity in PD patients during anticipation of loss or gain, an event-related functional magnetic resonance imaging experiment using a monetary incentive delay task was employed in 10 patients with PD and 10 healthy controls. A repeated-measures ANOVA to identify effects of group (PD vs. Control) and condition (anticipation of loss vs. gain vs. neutral outcome) revealed that patients with PD showed significantly reduced bilateral ventral striatal activation during reward anticipation but increased activity during loss anticipation. Within the patient group, the degree of activation in the ventral striatum during loss-anticipation was positively correlated with harm avoidance and negatively correlated with novelty seeking. These findings suggest that behavioural impairments in panic disorder may be related to abnormal neural processing of motivational cues. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. A direct comparison of appetitive and aversive anticipation: Overlapping and distinct neural activation.

    Sege, Christopher T; Bradley, Margaret M; Weymar, Mathias; Lang, Peter J

    2017-05-30

    fMRI studies of reward find increased neural activity in ventral striatum and medial prefrontal cortex (mPFC), whereas other regions, including the dorsolateral prefrontal cortex (dlPFC), anterior cingulate cortex (ACC), and anterior insula, are activated when anticipating aversive exposure. Although these data suggest differential activation during anticipation of pleasant or of unpleasant exposure, they also arise in the context of different paradigms (e.g., preparation for reward vs. threat of shock) and participants. To determine overlapping and unique regions active during emotional anticipation, we compared neural activity during anticipation of pleasant or unpleasant exposure in the same participants. Cues signalled the upcoming presentation of erotic/romantic, violent, or everyday pictures while BOLD activity during the 9-s anticipatory period was measured using fMRI. Ventral striatum and a ventral mPFC subregion were activated when anticipating pleasant, but not unpleasant or neutral, pictures, whereas activation in other regions was enhanced when anticipating appetitive or aversive scenes. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Potential genetic anticipation in hereditary leiomyomatosis-renal cell cancer (HLRCC).

    Wong, Mei Hua; Tan, Chuen Seng; Lee, Soo Chin; Yong, Yvonne; Ooi, Aik Seng; Ngeow, Joanne; Tan, Min Han

    2014-06-01

    Hereditary leiomyomatosis-renal cell cancer (HLRCC) is an autosomal dominant disorder characterised by cutaneous leiomyomas, symptomatic uterine leiomyomas and aggressive type II papillary renal cell carcinoma. It is caused by heterozygous mutations in the fumarate hydratase (FH) gene on chromosome 1q43. We present evidence of genetic anticipation in HLRCC syndrome. A comprehensive literature review was performed to determine the potential for genetic anticipation in HLRCC syndrome. The normal random effects model was used to evaluate for genetic anticipation to ensure reduction in bias. A total of 11 FH kindreds with available multi-generational data were identified for analysis. The mean difference in age at diagnosis of RCC between the first and second generation was -18.6 years (95 % CI -26.6 to -10.6, p anticipation for uterine leiomyomas was observed (p = 0.349). We report preliminary evidence of genetic anticipation of RCC in HLRCC syndrome. Additional clinical validation is important to confirm this observation, which may have practical implications on counseling and timing of surveillance initiation. Exploration of the underlying mechanisms of anticipation in HLRCC would be of considerable biological interest.

  4. Anticipation of peer evaluation in anxious adolescents: divergence in neural activation and maturation.

    Spielberg, Jeffrey M; Jarcho, Johanna M; Dahl, Ronald E; Pine, Daniel S; Ernst, Monique; Nelson, Eric E

    2015-08-01

    Adolescence is the time of peak onset for many anxiety disorders, particularly Social Anxiety Disorder. Research using simulated social interactions consistently finds differential activation in several brain regions in anxious (vs non-anxious) youth, including amygdala, striatum and medial prefrontal cortex. However, few studies examined the anticipation of peer interactions, a key component in the etiology and maintenance of anxiety disorders. Youth completed the Chatroom Task while undergoing functional magnetic resonance imaging. Patterns of neural activation were assessed in anxious and non-anxious youth as they were cued to anticipate social feedback from peers. Anxious participants evidenced greater amygdala activation and rostral anterior cingulate (rACC)↔amygdala coupling than non-anxious participants during anticipation of feedback from peers they had previously rejected; anxious participants also evidenced less nucleus accumbens activation during anticipation of feedback from selected peers. Finally, anxiety interacted with age in rACC: in anxious participants, age was positively associated with activation to anticipated feedback from rejected peers and negatively for selected peers, whereas the opposite pattern emerged for non-anxious youth. Overall, anxious youth showed greater reactivity in anticipation of feedback from rejected peers and thus may ascribe greater salience to these potential interactions and increase the likelihood of avoidance behavior. © The Author (2014). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  5. Anticipation of Negative Pictures Enhances the P2 and P3 in Their Later Recognition.

    Lin, Huiyan; Xiang, Jing; Li, Saili; Liang, Jiafeng; Jin, Hua

    2015-01-01

    Anticipation of emotional pictures has been found to be relevant to the encoding of the pictures as well as their later recognition performance. However, it is as yet unknown whether anticipation modulates neural activity in the later recognition of emotional pictures. To address this issue, participants in the present study were asked to view emotional (negative or neutral) pictures. The picture was preceded by a cue which indicated the emotional content of the picture in half of the trials (the anticipated condition) and without any cues in the other half (the unanticipated condition). Subsequently, participants had to perform an unexpected old/new recognition task in which old and novel pictures were presented without any preceding cues. Electroencephalography data was recorded during the recognition phase. Event-related potential results showed that for negative pictures, P2 and P3 amplitudes were larger in the anticipated as compared to the unanticipated condition; whereas this anticipation effect was not shown for neutral pictures. The present findings suggest that anticipation of negative pictures may enhance neural activity in their later recognition.

  6. Pain anticipation: an activation likelihood estimation meta-analysis of brain imaging studies.

    Palermo, Sara; Benedetti, Fabrizio; Costa, Tommaso; Amanzio, Martina

    2015-05-01

    The anticipation of pain has been investigated in a variety of brain imaging studies. Importantly, today there is no clear overall picture of the areas that are involved in different studies and the exact role of these regions in pain expectation remains especially unexploited. To address this issue, we used activation likelihood estimation meta-analysis to analyze pain anticipation in several neuroimaging studies. A total of 19 functional magnetic resonance imaging were included in the analysis to search for the cortical areas involved in pain anticipation in human experimental models. During anticipation, activated foci were found in the dorsolateral prefrontal, midcingulate and anterior insula cortices, medial and inferior frontal gyri, inferior parietal lobule, middle and superior temporal gyrus, thalamus, and caudate. Deactivated foci were found in the anterior cingulate, superior frontal gyrus, parahippocampal gyrus and in the claustrum. The results of the meta-analytic connectivity analysis provide an overall view of the brain responses triggered by the anticipation of a noxious stimulus. Such a highly distributed perceptual set of self-regulation may prime brain regions to process information where emotion, action and perception as well as their related subcategories play a central role. Not only do these findings provide important information on the neural events when anticipating pain, but also they may give a perspective into nocebo responses, whereby negative expectations may lead to pain worsening. © 2014 Wiley Periodicals, Inc.

  7. Unravelling nocebo effect: the mediating effect of anxiety between anticipation and pain at wound dressing change.

    Woo, Kevin Y

    2015-07-01

    The purpose of this study was to examine the mediating effect of anxiety in the relationship between anticipation and pain in people with chronic wounds. Pain is common in people with chronic wounds. Anticipation or negative expectation of discomfort has been shown to have an augmenting effect on pain; also known as nocebo hyperalgesia. This was a cross-sectional study with repeated measures. Prior to dressing change, anticipatory pain level was evaluated by a 11-point numerical rating scale and anxiety by the Six-items State-Trait Anxiety Inventory (STAI-6). During wound dressing changes, pain was measured before dressing removal, at dressing removal, at cleansing and dressing application using the numerical scale. Analysis was completed based on the data from a convenience sample of 96 patients. Participants reported more pain at cleansing and dressing removal than baseline. High levels of anticipation, anxiety and pain at dressing change for wounds were related to heavy exudate and wound that were covered with necrotic tissue. Finally, the relationship between anticipation and pain perception was mediated by anxiety. Anticipation of pain triggers anxiety that can lead to increased pain. There is a need to incorporate evaluation of anxiety and personal expectations as part of comprehensive pain assessment. Clinicians should be aware of the impact of emotions and anticipation on overall pain experience. © 2015 John Wiley & Sons Ltd.

  8. Anticipated stigma and quality of life among people living with chronic illnesses.

    Earnshaw, Valerie A; Quinn, Diane M; Park, Crystal L

    2012-06-01

    We examined the process by which anticipated stigma relates to quality of life among people living with chronic illnesses. We hypothesized that stress, social support and patient satisfaction mediate the relationships between three sources of anticipated stigma and quality of life. Data were collected from adults living with chronic illnesses recruited from support groups and online communities, and were analysed with path analysis. Results demonstrated that stress mediated the relationships between anticipated stigma from friends and family, and work colleagues with quality of life; social support mediated the relationships between anticipated stigma from friends and family, and work colleagues with quality of life; and patient satisfaction mediated the relationship between anticipated stigma from healthcare providers with quality of life. The final path model fit the data well (χ (2) (8) = 8.66, p = 0.37; RMSEA = 0.02; CFI = 0.99; SRMR = 0.03), and accounted for 60% of the variance in participants' quality of life. This work highlights potential points of intervention to improve quality of life. It calls attention to the importance of differentiating between sources of anticipated stigma in clinical settings, interventions and research involving people living with chronic illnesses.

  9. Neighbourhood Centres – Organisation, Management and Finance

    Larsen, Jacob Norvig

    to identify different financial models and analyse economic sustainability. As regards organisational and management models data were collected through documentary sources and by means of personal interviews and field visits to ten centres. Even within the analysed limited population of centres economic...... public subsidy. Some of the centres have high number of users on a daily basis, whereas others are only rarely used. It is explored how organisation, management and financial set-up differs among the centres. Quantitative data on financial issues and annual accounts of fifteen centres were analysed...... and institutional sustainability varies significantly. In organisational terms centres range from fully-integrated in the municipal administration to independent voluntary managed centres. In terms of financial, or economic, models variation is less pronounced as all centres to some degree are dependent on current...

  10. Institutional Support : Centre for Research and Technology ...

    year-old science and technology research centre at Maseno University in western Kenya. The Centre focuses on science and technology research to influence both national policies and development practices at the community level. Currently ...

  11. Japanese maintenance centres strive for greater realism

    Nedderman, J.

    1987-01-01

    Japanese utilities have devoted considerable efforts to ensuring that realistic plant conditions are simulated at their maintenance centres. In some centres, eg that of Kansai Electric Power Co, realism extends to difficult access, limited lighting and restricted ventilation. (author)

  12. Report: Cultural Research Centre (CRC)

    Cross-Cultural Foundation of Uganda

    2010-01-01

    This report arises from research carried out in Iganga and Namutumba districts in late 2006/early 2007 by the Cultural Research Centre (CRC), based in Jinja. Our research focus was to gauge the impact of using Lusoga as a medium of instruction (since 2005 in "pilot" lower primary classes) within and outside the classroom. This initiative was in response to a new set of circumstances in the education sector in Uganda, especially the introduction by Government of teaching in local languages in ...

  13. Radwaste Treatment Centre Jaslovske Bohunice

    2000-01-01

    In this leaflet the Bohunice Radwaste Treatment Centre (BSC RAO) is presented. BSC RAO is designed to process and treat liquid and solid radwaste, arising from the NPP A-1 decommissioning, from NPPs V-1, V-2, and Mochovce operations, as well as institutional radwaste of diverse institutional (hospitals, research institutes) in the Slovak Republic. Transport, sorting, incineration, compacting, concentration and cementation of radwaste as well as monitoring of emission are described

  14. An evaluation of the utilisation of the virtual environment for radiotherapy training (VERT) in clinical radiotherapy centres across the UK

    James, Sarah; Dumbleton, Claire

    2013-01-01

    Aim: The purpose of the survey was to evaluate the utilisation of the Virtual Environment for Radiotherapy Training (VERT) in clinical radiotherapy centres across the UK. Methods: A survey questionnaire was constructed using the Survey Monkey™ tool to evaluate the utilisation of the Virtual Environment for Radiotherapy Training. Once constructed, an online link to the survey questionnaire was emailed to all radiotherapy centre managers in the UK (n = 67) who were invited to provide one response per centre. The survey comprised forty-five questions which were grouped into eleven sections. Key results: The results indicate that 61% of UK radiotherapy centres have VERT installed, twenty centres are currently without a VERT installation and only 1 centre is intending to install a system in the near future. The results also indicate that the use of VERT varies considerably in differing radiotherapy centres with the most frequent use of VERT being for the training of staff, specifically for the training of pre-registration therapeutic radiographers and preparation time for trainers. The majority of centres using VERT for any of the purposes investigated feel it provides benefits. Conclusions and recommendations: The survey highlighted the varied use of VERT in radiotherapy centres across the UK and indicated that when VERT is used in clinical radiotherapy centres, a wide variety of benefits are experienced. Because of the variation in use, it is concluded that the benefits of the VERT installations in radiotherapy centres across the UK are not being fully realised. It is recommended that all radiotherapy service managers commit adequate resources to develop and implement VERT fully and effectively so that its full potential is realised in all radiotherapy centres across the UK

  15. Family-centred care delivery

    Mayo-Bruinsma, Liesha; Hogg, William; Taljaard, Monica; Dahrouge, Simone

    2013-01-01

    Abstract Objective To determine whether models of primary care service delivery differ in their provision of family-centred care (FCC) and to identify practice characteristics associated with FCC. Design Cross-sectional study. Setting Primary care practices in Ontario (ie, 35 salaried community health centres, 35 fee-for-service practices, 32 capitation-based health service organizations, and 35 blended remuneration family health networks) that belong to 4 models of primary care service delivery. Participants A total of 137 practices, 363 providers, and 5144 patients. Main outcome measures Measures of FCC in patient and provider surveys were based on the Primary Care Assessment Tool. Statistical analyses were conducted using linear mixed regression models and generalized estimating equations. Results Patient-reported FCC scores were high and did not vary significantly by primary care model. Larger panel size in a practice was associated with lower odds of patients reporting FCC. Provider-reported FCC scores were significantly higher in community health centres than in family health networks (P = .035). A larger number of nurse practitioners and clinical services on-site were both associated with higher FCC scores, while scores decreased as the number of family physicians in a practice increased and if practices were more rural. Conclusion Based on provider and patient reports, primary care reform strategies that encourage larger practices and more patients per family physician might compromise the provision of FCC, while strategies that encourage multidisciplinary practices and a range of services might increase FCC. PMID:24235195

  16. Benefits of Exercise

    ... activity into your life. To get the most benefit, you should try to get the recommended amount ... likely even live longer. What are the health benefits of exercise? Regular exercise and physical activity may ...

  17. Medicare Hospice Benefits

    CENTERS for MEDICARE & MEDICAID SERVICES Medicare Hospice Benefits This official government booklet includes information about Medicare hospice benefits: Who’s eligible for hospice care What services are included in hospice care How ...

  18. Employee motivation and benefits

    Březíková, Tereza

    2009-01-01

    The topic of my bachelor's thesis is the employee motivation and benefits. The thesis is divided in two parts, a theoretical one and a practical one. The theoretical part deals with the theory of motivation and individual employee benefits. The practical part describes employee benefits in ČSOB, where I did my research by questionnaires that were filled in by employees from different departments of ČSOB. These employees answered questions about their work motivation and benefits. The resultts...

  19. The self-regulatory role of anticipated group-based shame and guilt in inhibiting in-group favoritism

    Shepherd, Lee; Spears, Russell; Manstead, Antony Stephen

    2013-01-01

    In three studies, we examined whether the anticipation of group-based guilt and shame inhibits in-group favoritism. In Studies 1 and 2, anticipated group-based shame negatively predicted in-group favoritism; in neither study did anticipated group-based guilt uniquely predict in-group favoritism. In

  20. The Aube storage centre: Annual report 2010

    2011-01-01

    After a presentation of the Aube storage centre, a storage centre for low and intermediate activity nuclear wastes, this report gives an overview of measures related to nuclear security, to radioprotection and to nuclear safety. It indicates the incidents and accidents which occurred in 2010, describes how the centre's wastes are managed, and indicates the actions performed in terms of public information

  1. Analysis of benefits

    Kováříková, Kamila

    2012-01-01

    This master thesis deals with employee benefits in the current labour market, especially from the perspective of young employees. The first part is focused on the theory of motivation and employee benefits also with their tax impact on employee's income. Employee benefits in the current labour market, employee's satisfaction and employer's attitude to this issue are analyzed in the second part of this thesis.

  2. The DIY Digital Medical Centre.

    Timmis, James Kenneth; Timmis, Kenneth

    2017-09-01

    Healthcare systems worldwide are confronted with major economic, organizational and logistical challenges. Historic evolution of health care has led to significant healthcare sector fragmentation, resulting in systemic inefficiencies and suboptimal resource exploitation. To attain a sustainable healthcare model, fundamental, system-wide improvements that effectively network, and ensure fulfilment of potential synergies between sectors, and include and facilitate coherent strategic planning and organisation of healthcare infrastructure are needed. Critically, they must be specifically designed to sustainably achieve peak performance within the current policy environment for cost-control, and efficiency and quality improvement for service delivery. We propose creation of a new healthcare cluster, to be embedded in existing healthcare systems. It consists of (i) local 24/7 walk-in virtually autonomous do-it-yourself Digital Medical Centres performing routine diagnosis, monitoring, prevention, treatment and standardized documentation and health outcome assessment/reporting, which are online interfaced with (ii) regional 24/7 eClinician Centres providing on-demand clinical supervision/assistance to Digital Medical Centre patients. Both of these are, in turn, online interfaced with (iii) the National Clinical Informatics Centre, which houses the national patient data centre (cloud) and data analysis units that conduct patient- and population-level, personalized and predictive(-medicine) intervention optimization analyses. The National Clinical Informatics Centre also interfaces with biomedical research and prioritizes and accelerates the translation of new discoveries into clinical practice. The associated Health Policy Innovation and Evaluation Centre rapidly integrates new findings with health policy/regulatory discussions. This new cluster would synergistically link all health system components in a circular format, enable not only access by all arms of the health

  3. Is it Worth the Effort? Novel Insights into Obesity-Associated Alterations in Cost-Benefit Decision-Making

    Mathar, David; Horstmann, Annette; Pleger, Burkhard; Villringer, Arno; Neumann, Jane

    2016-01-01

    Cost-benefit decision-making entails the process of evaluating potential actions according to the trade-off between the expected reward (benefit) and the anticipated effort (costs). Recent research revealed that dopaminergic transmission within the fronto-striatal circuitry strongly modulates cost-benefit decision-making. Alterations within the dopaminergic fronto-striatal system have been associated with obesity, but little is known about cost-benefit decision-making differences in obese com...

  4. Energy efficiency in U.K. shopping centres

    Mangiarotti, Michela

    Energy efficiency in shopping centres means providing comfortable internal environment and services to the occupants with minimum energy use in a cost-effective and environmentally sensitive manner. This research considers the interaction of three factors affecting the energy efficiency of shopping centres: i) performance of the building fabric and services ii) management of the building in terms of operation, control, maintenance and replacement of the building fabric and services, and company's energy policy iii) occupants' expectation for comfort and awareness of energy efficiency. The aim of the investigation is to determine the role of the above factors in the energy consumption and carbon emissions of shopping centres and the scope for reducing this energy usage by changing one or all the three factors. The study also attempts to prioritize the changes in the above factors that are more cost-effective at reducing that energy consumption and identify the benefits and main economic and legal drivers for energy efficiency in shopping centres. To achieve these targets, three case studies have been analysed. Using energy data from bills, the performance of the selected case studies has been assessed to establish trends and current energy consumption and carbon emissions of shopping centres and their related causes. A regression analysis has attempted to break down the energy consumption of the landlords' area by end-use to identify the main sources of energy usage and consequently introduce cost-effective measures for saving energy. A monitoring and occupants' survey in both landlords' and tenants' areas have been carried out at the same time to compare the objective data of the environmental conditions with the subjective impressions of shoppers and shopkeepers. In particular, the monitoring aimed at assessing the internal environment to identify possible causes of discomfort and opportunities for introducing energy saving measures. The survey looked at

  5. Sensorimotor synchronization with tempo-changing auditory sequences: Modeling temporal adaptation and anticipation.

    van der Steen, M C Marieke; Jacoby, Nori; Fairhurst, Merle T; Keller, Peter E

    2015-11-11

    The current study investigated the human ability to synchronize movements with event sequences containing continuous tempo changes. This capacity is evident, for example, in ensemble musicians who maintain precise interpersonal coordination while modulating the performance tempo for expressive purposes. Here we tested an ADaptation and Anticipation Model (ADAM) that was developed to account for such behavior by combining error correction processes (adaptation) with a predictive temporal extrapolation process (anticipation). While previous computational models of synchronization incorporate error correction, they do not account for prediction during tempo-changing behavior. The fit between behavioral data and computer simulations based on four versions of ADAM was assessed. These versions included a model with adaptation only, one in which adaptation and anticipation act in combination (error correction is applied on the basis of predicted tempo changes), and two models in which adaptation and anticipation were linked in a joint module that corrects for predicted discrepancies between the outcomes of adaptive and anticipatory processes. The behavioral experiment required participants to tap their finger in time with three auditory pacing sequences containing tempo changes that differed in the rate of change and the number of turning points. Behavioral results indicated that sensorimotor synchronization accuracy and precision, while generally high, decreased with increases in the rate of tempo change and number of turning points. Simulations and model-based parameter estimates showed that adaptation mechanisms alone could not fully explain the observed precision of sensorimotor synchronization. Including anticipation in the model increased the precision of simulated sensorimotor synchronization and improved the fit of model to behavioral data, especially when adaptation and anticipation mechanisms were linked via a joint module based on the notion of joint internal

  6. Altered brain activation and connectivity during anticipation of uncertain threat in trait anxiety.

    Geng, Haiyang; Wang, Yi; Gu, Ruolei; Luo, Yue-Jia; Xu, Pengfei; Huang, Yuxia; Li, Xuebing

    2018-06-08

    In the research field of anxiety, previous studies generally focus on emotional responses following threat. A recent model of anxiety proposes that altered anticipation prior to uncertain threat is related with the development of anxiety. Behavioral findings have built the relationship between anxiety and distinct anticipatory processes including attention, estimation of threat, and emotional responses. However, few studies have characterized the brain organization underlying anticipation of uncertain threat and its role in anxiety. In the present study, we used an emotional anticipation paradigm with functional magnetic resonance imaging (fMRI) to examine the aforementioned topics by employing brain activation and general psychophysiological interactions (gPPI) analysis. In the activation analysis, we found that high trait anxious individuals showed significantly increased activation in the thalamus, middle temporal gyrus (MTG), and dorsomedial prefrontal cortex (dmPFC), as well as decreased activation in the precuneus, during anticipation of uncertain threat compared to the certain condition. In the gPPI analysis, the key regions including the amygdala, dmPFC, and precuneus showed altered connections with distributed brain areas including the ventromedial prefrontal cortex (vmPFC), dorsolateral prefrontal cortex (dlPFC), inferior parietal sulcus (IPS), insula, para-hippocampus gyrus (PHA), thalamus, and MTG involved in anticipation of uncertain threat in anxious individuals. Taken together, our findings indicate that during the anticipation of uncertain threat, anxious individuals showed altered activations and functional connectivity in widely distributed brain areas, which may be critical for abnormal perception, estimation, and emotion reactions during the anticipation of uncertain threat. © 2018 Wiley Periodicals, Inc.

  7. Intolerance of uncertainty mediates reduced reward anticipation in major depressive disorder.

    Nelson, Brady D; Shankman, Stewart A; Proudfit, Greg H

    2014-04-01

    Reduced reward sensitivity has long been considered a fundamental deficit of major depressive disorder (MDD). One way this deficit has been measured is by an asymmetry in electroencephalogram (EEG) activity between left and right frontal brain regions. MDD has been associated with a reduced frontal EEG asymmetry (i.e., decreased left relative to right) while anticipating reward. However, the mechanism (or mediator) of this association is unclear. The present study examined whether intolerance of uncertainty (IU) mediated the association between depression and reduced reward anticipation. Data were obtained from a prior study reporting reduced frontal EEG asymmetry while anticipating reward in early-onset MDD. Participants included 156 individuals with early-onset MDD-only, panic disorder-only, both (comorbids), or controls. Frontal EEG asymmetry was recorded during an uncertain reward anticipation task. Participants completed a self-report measure of IU. All three psychopathology groups reported greater IU relative to controls. Across all participants, greater IU was associated with a reduced frontal EEG asymmetry. Furthermore, IU mediated the relationship between MDD and frontal EEG asymmetry and results remained significant after controlling for neuroticism, suggesting effects were not due to broad negative affectivity. MDD participants were limited to those with early-onset depression. Measures were collected cross-sectionally, precluding causal relationships. IU mediated the relationship between MDD and reduced reward anticipation, independent of neuroticism. Explanations are provided regarding how IU may contribute to reduced reward anticipation in depression. Overall, IU appears to be an important mechanism for the association between depression and reduced reward anticipation. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. Elevated amygdala activity during reappraisal anticipation predicts anxiety in avoidant personality disorder.

    Denny, Bryan T; Fan, Jin; Liu, Xun; Ochsner, Kevin N; Guerreri, Stephanie; Mayson, Sarah Jo; Rimsky, Liza; McMaster, Antonia; New, Antonia S; Goodman, Marianne; Siever, Larry J; Koenigsberg, Harold W

    2015-02-01

    Avoidant personality disorder is characterized by pervasive anxiety, fear of criticism, disapproval, and rejection, particularly in anticipation of exposure to social situations. An important but underexplored question concerns whether anxiety in avoidant patients is associated with an impaired ability to engage emotion regulatory strategies in anticipation of and during appraisal of negative social stimuli. We examined the use of an adaptive emotion regulation strategy, cognitive reappraisal, in avoidant patients. In addition to assessing individual differences in state and trait anxiety levels, self-reported affect as well as measures of neural activity were compared between 17 avoidant patients and 21 healthy control participants both in anticipation of and during performance of a reappraisal task. Avoidant patients showed greater state and trait-related anxiety relative to healthy participants. In addition, relative to healthy participants, avoidant patients showed pronounced amygdala hyper-reactivity during reappraisal anticipation, and this hyper-reactivity effect was positively associated with increasing self-reported anxiety levels. Our finding of exaggerated amygdala activity during reappraisal anticipation could reflect anxiety about the impending need to reappraise, anxiety about the certainty of an upcoming negative image, or anxiety relating to anticipated scrutiny of task responses by the experimenters. While we believe that all of these possibilities are consistent with the phenomenology of avoidant personality disorder, future research may clarify this ambiguity. These results suggest that amygdala reactivity in anticipation of receiving negative social information may represent a key component of the neural mechanisms underlying the heightened anxiety present in avoidant patients. Published by Elsevier B.V.

  9. Medial prefrontal brain activation to anticipated reward and loss in obsessive-compulsive disorder.

    Kaufmann, C; Beucke, J C; Preuße, F; Endrass, T; Schlagenhauf, F; Heinz, A; Juckel, G; Kathmann, N

    2013-01-01

    Obsessive-compulsive disorder (OCD) is associated with dysfunctional brain activity in several regions which are also involved in the processing of motivational stimuli. Processing of reward and punishment appears to be of special importance to understand clinical symptoms. There is evidence for higher sensitivity to punishment in patients with OCD which raises the question how avoidance of punishment relates to activity within the brain's reward circuitry. We employed the monetary incentive delay task paradigm optimized for modeling the anticipation phase of immediate reward and punishment, in the context of a cross-sectional event-related FMRI study comparing OCD patients and healthy control participants (n = 19 in each group). While overall behavioral performance was similar in both groups, patients showed increased activation upon anticipated losses in a medial and superior frontal cortex region extending into the cingulate cortex, and decreased activation upon anticipated rewards. No evidence was found for altered activation of dorsal or ventral striatal regions. Patients also showed more delayed responses for anticipated rewards than for anticipated losses whereas the reverse was true in healthy participants. The medial prefrontal cortex has been shown to implement a domain-general process comprising negative affect, pain and cognitive control. This process uses information about punishment to control aversively motivated actions by integrating signals arriving from subcortical regions. Our results support the notion that OCD is associated with altered sensitivity to anticipated rewards and losses in a medial prefrontal region whereas there is no significant aberrant activation in ventral or dorsal striatal brain regions during processing of reinforcement anticipation.

  10. Altered brain activity during reward anticipation in pathological gambling and obsessive-compulsive disorder.

    Jung-Seok Choi

    Full Text Available BACKGROUND: Pathological gambling (PG and obsessive-compulsive disorder (OCD are conceptualized as a behavioral addiction, with a dependency on repetitive gambling behavior and rewarding effects following compulsive behavior, respectively. However, no neuroimaging studies to date have examined reward circuitry during the anticipation phase of reward in PG compared with in OCD while considering repetitive gambling and compulsion as addictive behaviors. METHODS/PRINCIPAL FINDINGS: To elucidate the neural activities specific to the anticipation phase of reward, we performed event-related functional magnetic resonance imaging (fMRI in young adults with PG and compared them with those in patients with OCD and healthy controls. Fifteen male patients with PG, 13 patients with OCD, and 15 healthy controls, group-matched for age, gender, and IQ, participated in a monetary incentive delay task during fMRI scanning. Neural activation in the ventromedial caudate nucleus during anticipation of both gain and loss decreased in patients with PG compared with that in patients with OCD and healthy controls. Additionally, reduced activation in the anterior insula during anticipation of loss was observed in patients with PG compared with that in patients with OCD which was intermediate between that in OCD and healthy controls (healthy controls < PG < OCD, and a significant positive correlation between activity in the anterior insula and South Oaks Gambling Screen score was found in patients with PG. CONCLUSIONS: Decreased neural activity in the ventromedial caudate nucleus during anticipation may be a specific neurobiological feature for the pathophysiology of PG, distinguishing it from OCD and healthy controls. Correlation of anterior insular activity during loss anticipation with PG symptoms suggests that patients with PG fit the features of OCD associated with harm avoidance as PG symptoms deteriorate. Our findings have identified functional disparities and

  11. Medical futility decisions and physicians' legal defensiveness: the impact of anticipated conflict on thresholds for end-of-life treatment.

    Swanson, J W; McCrary, S V

    1996-01-01

    Does legal defensiveness significantly influence physicians' assessments of medical futility, in ways that may adversely affect the rights of patients and their family members to make their own health care decisions at the end of life? This exploratory study addresses that question with attitudinal data from a survey of 301 physicians practicing in academic medical centers in Texas. The majority of respondents indicated that the probability of success defining futile treatment should hypothetically be lower for patients with potential to benefit more from life-sustaining medical intervention (e.g. typically patients who are sentient), and higher for patients with less potential to benefit (e.g. patients in a persistent vegetative state). That is to say, physicians normally perceive longer odds to be worth pursuing for greater potential gain - a position that seems logically consonant with patients' rational self-interest. However, physicians with an attitude of extreme legal defensiveness did not fit this pattern. Rather, they tended to define futility in a manner that would maximize the physician's latitude to justifiably oppose patient preferences for end-of-life treatment abatement. These findings suggest that some physicians assume an adversarial position in their consideration of medical futility issues - an attitude that anticipates conflict with terminally-ill patients or their surrogates. The analysis presented here is not definitive, but at least raises the question of whether some physicians may inappropriately use their prerogative over medical futility as a means to guard their professional autonomy against perceived threats.

  12. Psychological capital, work engagement and organisational commitment amongst call centre employees in South Africa

    Janet C. Simons

    2013-11-01

    Research purpose: The purpose of the research was to determine the relationship between psychological capital, work engagement and organisational commitment amongst call centre employees; and further, to determine whether psychological capital and work engagement hold predictive value for the organisational commitment of call centre employees. Motivation for the study: There is a gap in research in understanding and enabling positive resource capacities in highly stressful work contexts such as call centres. Research design, approach and method: A cross-sectional survey design was used. A sample of 106 call centre employees from a South African organisation participated in the research. The measuring instruments included a demographic questionnaire, the Psychological Capital Questionnaire (PCQ, the Utrecht Work Engagement Scale (UWES and the Organisational Commitment Questionnaire (OCQ. Main findings: Significant positive relationships were found between psychological capital, work engagement and organisational commitment. The results showed work engagement as being the only significant predictor of organisational commitment. Practical/managerial implications: Call centre employers need to develop and implement workplace interventions that would increase the psychological capital of call centre employees. Contribution/value-add: The research findings will benefit both call centre employees and management. The study highlighted the importance of the role of optimism as a subdimension of psychological capital in developing work engagement and organisational commitment amongst call centre employees.

  13. How to predict a high rate of inappropriateness for upper endoscopy in an endoscopic centre?

    Buri, L; Bersani, G; Hassan, C; Anti, M; Bianco, M A; Cipolletta, L; Di Giulio, E; Di Matteo, G; Familiari, L; Ficano, L; Loriga, P; Morini, S; Pietropaolo, V; Zambelli, A; Grossi, E; Intraligi, M; Tessari, F; Buscema, M

    2010-09-01

    Inappropriateness of upper endoscopy (EGD) indication causes decreased diagnostic yield. Our aim of was to identify predictors of appropriateness rate for EGD among endoscopic centres. A post-hoc analysis of two multicentre cross-sectional studies, including 6270 and 8252 patients consecutively referred to EGD in 44 (group A) and 55 (group B) endoscopic Italian centres in 2003 and 2007, respectively, was performed. A multiple forward stepwise regression was applied to group A, and independently validated in group B. A <70% threshold was adopted to define inadequate appropriateness rate clustered by centre. discrete variability of clustered appropriateness rates among the 44 group A centres was observed (median: 77%; range: 41-97%), and a <70% appropriateness rate was detected in 11 (25%). Independent predictors of centre appropriateness rate were: percentage of patients referred by general practitioners (GP), rate of urgent examinations, prevalence of relevant diseases, and academic status. For group B, sensitivity, specificity and area under receiver operating characteristic curve of the model in detecting centres with a <70% appropriateness rate were 54%, 93% and 0.72, respectively. A simple predictive rule, based on rate of patients referred by GPs, rate of urgent examinations, prevalence of relevant diseases and academic status, identified a small subset of centres characterised by a high rate of inappropriateness. These centres may be presumed to obtain the largest benefit from targeted educational programs. Copyright (c) 2010 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

  14. Anticipation-related brain connectivity in bipolar and unipolar depression: a graph theory approach.

    Manelis, Anna; Almeida, Jorge R C; Stiffler, Richelle; Lockovich, Jeanette C; Aslam, Haris A; Phillips, Mary L

    2016-09-01

    Bipolar disorder is often misdiagnosed as major depressive disorder, which leads to inadequate treatment. Depressed individuals versus healthy control subjects, show increased expectation of negative outcomes. Due to increased impulsivity and risk for mania, however, depressed individuals with bipolar disorder may differ from those with major depressive disorder in neural mechanisms underlying anticipation processes. Graph theory methods for neuroimaging data analysis allow the identification of connectivity between multiple brain regions without prior model specification, and may help to identify neurobiological markers differentiating these disorders, thereby facilitating development of better therapeutic interventions. This study aimed to compare brain connectivity among regions involved in win/loss anticipation in depressed individuals with bipolar disorder (BDD) versus depressed individuals with major depressive disorder (MDD) versus healthy control subjects using graph theory methods. The study was conducted at the University of Pittsburgh Medical Center and included 31 BDD, 39 MDD, and 36 healthy control subjects. Participants were scanned while performing a number guessing reward task that included the periods of win and loss anticipation. We first identified the anticipatory network across all 106 participants by contrasting brain activation during all anticipation periods (win anticipation + loss anticipation) versus baseline, and win anticipation versus loss anticipation. Brain connectivity within the identified network was determined using the Independent Multiple sample Greedy Equivalence Search (IMaGES) and Linear non-Gaussian Orientation, Fixed Structure (LOFS) algorithms. Density of connections (the number of connections in the network), path length, and the global connectivity direction ('top-down' versus 'bottom-up') were compared across groups (BDD/MDD/healthy control subjects) and conditions (win/loss anticipation). These analyses showed that

  15. Power of Pets: Health Benefits of Human-Animal Interactions

    ... partnered with the Mars Corporation’s WALTHAM Centre for Pet Nutrition to answer questions like these by funding research studies. Scientists are looking at what the potential physical and mental health benefits are for different animals—from fish to ...

  16. How health leaders can benefit from predictive analytics.

    Giga, Aliyah

    2017-11-01

    Predictive analytics can support a better integrated health system providing continuous, coordinated, and comprehensive person-centred care to those who could benefit most. In addition to dollars saved, using a predictive model in healthcare can generate opportunities for meaningful improvements in efficiency, productivity, costs, and better population health with targeted interventions toward patients at risk.

  17. Determination of benefit of early identification of severe forms of ...

    Background/Aims: A pilot study to determine benefits of early identification of severe forms of malaria in peripheral centres was carried out in 3 rural communities of South Eastern Nigeria. Methodology: The study area is located in the rain forest belt of South Eastern Nigeria with high temperature and humidity. It is a typical ...

  18. Discussion on 'Centres of excellence' in Africa

    Riad, S.

    1999-01-01

    In Africa, Centres of Excellence should be oriented to build up scientific and technological capacity in the four topics of international Monitoring System related technologies, namely, seismic monitoring, hydro acoustic monitoring, infrasound monitoring and radionuclides monitoring. Training programs on these topics should be a major objective. A network of such centres should be established in a number of African countries. Centres should be equipped with means and materials for on-line course dispatch to interested training centres or research institutions. African centres should develop strong relationship among themselves through information and data exchange and sharing, harmonization of training programs. National data centres may be established as a component of the African Centre of Excellence. States Signatories may authorize the establishment of a specific fund to support the activities of the African center

  19. Steeling Ourselves: Intragroup Communication while Anticipating Intergroup Contact Evokes Defensive Intergroup Perceptions.

    Greijdanus, Hedy; Postmes, Tom; Gordijn, Ernestine H; van Zomeren, Martijn

    2015-01-01

    Two experiments investigated the role of intragroup communication in intergroup conflict (de-)escalation. Experiment 1 examined the effects of intragroup communication (vs. individual thought) and anticipated face-to-face intergroup contact (vs. no anticipated face-to-face intergroup contact). The group discussions of stigmatized group members who anticipated face-to-face intergroup contact revolved more around intergroup hostility. This boosted ingroup identification and increased social creativity but also led to steeling (a hardening of perceived intergroup relations). In Experiment 2, new participants listened to the taped group discussions. The discussions of groups anticipating face-to-face intergroup contact evoked more intergroup anxiety-related discomfort than discussions of groups not anticipating face-to-face intergroup encounters. Together, these results support the idea that steeling is a defensive reaction to prepare for an anxiety-arousing intergroup confrontation. Although steeling is also associated with positive consequences such as increased ingroup solidarity and social creativity, this hardened stance may be an obstacle to conflict de-escalation.

  20. Neural responsivity during soft drink intake, anticipation, and advertisement exposure in habitually consuming youth.

    Burger, Kyle S; Stice, Eric

    2014-02-01

    Although soft drinks are heavily advertised, widely consumed, and have been associated with obesity, little is understood regarding neural responsivity to soft drink intake, anticipated intake, and advertisements. Functional MRI was used to assess examine neural response to carbonated soft drink intake, anticipated intake and advertisement exposure as well as milkshake intake in 27 adolescents that varied on soft drink consumer status. Intake and anticipated intake of carbonated Coke® activated regions implicated in gustatory, oral somatosensory, and reward processing, yet high-fat/sugar milkshake intake elicited greater activation in these regions vs. Coke intake. Advertisements highlighting the Coke product vs. nonfood control advertisements, but not the Coke logo, activated gustatory and visual brain regions. Habitual Coke consumers vs. nonconsumers showed greater posterior cingulate responsivity to Coke logo ads, suggesting that the logo is a conditioned cue. Coke consumers exhibited less ventrolateral prefrontal cortex responsivity during anticipated Coke intake relative to nonconsumers. Results indicate that soft drinks activate reward and gustatory regions, but are less potent in activating these regions than high-fat/sugar beverages, and imply that habitual soft drink intake promotes hyper-responsivity of regions encoding salience/attention toward brand specific cues and hypo-responsivity of inhibitory regions while anticipating intake. Copyright © 2013 The Obesity Society.

  1. Neural responsivity during soft drink intake, anticipation, and advertisement exposure in habitually consuming youth

    Burger, Kyle S.; Stice, Eric

    2014-01-01

    OBJECTIVE Although soft drinks are heavily advertised, widely consumed, and have been associated with obesity, little is understood regarding neural responsivity to soft drink intake, anticipated intake, and advertisements. METHODS Functional MRI was used to assess examine neural response to carbonated soft drink intake, anticipated intake and advertisement exposure as well as milkshake intake in 27 adolescents that varied on soft drink consumer status. RESULTS Intake and anticipated intake of carbonated Coke® activated regions implicated in gustatory, oral somatosensory, and reward processing, yet high-fat/sugar milkshake intake elicited greater activation in these regions versus Coke intake. Advertisements highlighting the Coke product vs. non-food control advertisements, but not the Coke logo, activated gustatory and visual brain regions. Habitual Coke consumers vs. non-consumers showed greater posterior cingulate responsivity to Coke logo ads, suggesting that the logo is a conditioned cue. Coke consumers exhibited less ventrolateral prefrontal cortex responsivity during anticipated Coke intake relative to non-consumers. CONCLUSIONS Results indicate that soft drinks activate reward and gustatory regions, but are less potent in activating these regions than high-fat/sugar beverages, and imply that habitual soft drink intake promotes hyper-responsivity of regions encoding salience/attention toward brand specific cues and hypo-responsivity of inhibitory regions while anticipating intake. PMID:23836764

  2. Neural Activation during Anticipation of Near Pain-Threshold Stimulation Among the Pain-Fearful

    Zhou Yang

    2016-07-01

    Full Text Available Fear of pain (FOP can increase risk for chronic pain and disability but little is known about corresponding neural responses in anticipation of potential pain. In this study, more (10 women, 6 men and less (7 women, 6 men pain-fearful groups underwent whole-brain functional magnetic resonance imaging (fMRI during anticipation of near pain-threshold stimulation. Groups did not differ in the proportion of stimuli judged to be painful but pain-fearful participants reported significantly more state fear prior to stimulus exposure. Within the entire sample, stronger activation was found in several pain regions (e.g., bilateral insula, midcingulate cortex (MCC, thalamus, superior frontal gyrus and visual areas linked to decoding stimulus valences (inferior orbital cortex during anticipation of painful stimuli. Between groups and correlation analyses indicated pain-fearful participants experienced comparatively more activity in regions implicated in evaluating potential threats and processing negative emotions during anticipation (i.e., MCC, mid occipital cortex, superior temporal pole, though group differences were not apparent in most so-called pain matrix regions. In sum, trait- and task-based FOP is associated with enhanced responsiveness in regions involved in threat processing and negative affect during anticipation of potentially painful stimulation.

  3. Anticipating synchronization in a chain of chaotic oscillators with switching parameters

    Pyragienė, T., E-mail: tatjana.pyragiene@ftmc.lt; Pyragas, K.

    2015-12-18

    A new coupling scheme for anticipating synchronization of chaotic systems is proposed. The scheme consists of a master system and two in series coupled slave systems with periodically switching parameters. The scheme does not require the presence of any time-delay terms either in a master or in slave systems and provides long-term anticipation. The value of anticipation time as well as the conditions of synchronization are derived in an analytical form. Analytical results are tested by numerical experiments with the chaotic Rössler and Lorenz systems as well as the Hindmarsh–Rose neuron in a regime of chaotic bursting. Also a robustness of the scheme with respect to parameter mismatch and noise is demonstrated. - Highlights: • A new coupling scheme for anticipating chaotic synchronization is proposed. • The scheme consists of three coupled systems with periodically switching parameters. • Long-term anticipation is achieved without using time-delay terms. • The method is verified for the Rössler, Lorenz and Hindmarsh–Rose neuron systems.

  4. Anticipating synchronization in a chain of chaotic oscillators with switching parameters

    Pyragienė, T.; Pyragas, K.

    2015-01-01

    A new coupling scheme for anticipating synchronization of chaotic systems is proposed. The scheme consists of a master system and two in series coupled slave systems with periodically switching parameters. The scheme does not require the presence of any time-delay terms either in a master or in slave systems and provides long-term anticipation. The value of anticipation time as well as the conditions of synchronization are derived in an analytical form. Analytical results are tested by numerical experiments with the chaotic Rössler and Lorenz systems as well as the Hindmarsh–Rose neuron in a regime of chaotic bursting. Also a robustness of the scheme with respect to parameter mismatch and noise is demonstrated. - Highlights: • A new coupling scheme for anticipating chaotic synchronization is proposed. • The scheme consists of three coupled systems with periodically switching parameters. • Long-term anticipation is achieved without using time-delay terms. • The method is verified for the Rössler, Lorenz and Hindmarsh–Rose neuron systems.

  5. Premenstrual dysphoric disorder and prefrontal reactivity during anticipation of emotional stimuli.

    Gingnell, Malin; Bannbers, Elin; Wikström, Johan; Fredrikson, Mats; Sundström-Poromaa, Inger

    2013-11-01

    Premenstrual disorder (PMDD) affects around 5% of women in childbearing ages. An increased sensitivity in emotion processing areas of the brain to variations in ovarian steroid levels has been suggested as part of the pathophysiology in PMDD, but prior neuroimaging studies of emotion processing are yet inconclusive. Previous behavioral studies of women with PMDD have, however, reported enhanced luteal phase startle responsivity during emotional anticipation. Here we used functional magnetic resonance imaging (fMRI) to investigate central neural circuitry activity during anticipation of, and exposure to, emotional stimuli across the menstrual cycle in women with and without PMDD. As compared to healthy controls, women with PMDD displayed significantly enhanced reactivity in the prefrontal cortex during anticipation of, but not exposure to, negative emotional stimuli during the luteal phase. In PMDD patients, BOLD reactivity during anticipation or viewing of negative emotional stimuli was not dependent on absolute levels of estradiol or progesterone. However, progesterone levels were positively correlated with emotion-induced reactivity in the dorsolateral prefrontal cortex to positive emotional stimuli. These findings suggest that cortical emotional circuitry reactivity during anticipation is altered in PMDD during the luteal phase, which might be part of the pathophysiology behind the emotional symptoms or lack of emotional control reported by women with PMDD. © 2013 Elsevier B.V. and ECNP. All rights reserved.

  6. Neural response during anticipation of monetary loss is elevated in adult attention deficit hyperactivity disorder.

    Wilbertz, Gregor; Delgado, Mauricio R; Tebartz Van Elst, Ludger; Maier, Simon; Philipsen, Alexandra; Blechert, Jens

    2017-06-01

    Risky behaviour seriously impacts the life of adult patients with attention deficit hyperactivity disorder (ADHD). Such behaviours have often been attributed to their exaggerated reward seeking, but dysfunctional anticipation of negative outcomes might also play a role. The present study compared adult patients with ADHD (n = 28) with matched healthy controls (n = 28) during anticipation of monetary losses versus gains while undergoing functional magnetic resonance imaging (fMRI) and skin conductance recording. Skin conductance was higher during anticipation of losses compared to gains in both groups. Affective ratings of predictive cues did not differ between groups. ADHD patients showed increased activity in bilateral amygdalae, left anterior insula (region of interest analysis) and left temporal pole (whole brain analysis) compared to healthy controls during loss versus gain anticipation. In the ADHD group higher insula and temporal pole activations went along with more negative affective ratings. Neural correlates of loss anticipation are not blunted but rather increased in ADHD, possibly due to a life history of repeated failures and the respective environmental sanctions. Behavioural adaptations to such losses, however, might differentiate them from controls: future research should study whether negative affect might drive more risk seeking than risk avoidance.

  7. Anticipation of a mentally effortful task recruits Dorsolateral Prefrontal Cortex: An fNIRS validation study.

    Vassena, Eliana; Gerrits, Robin; Demanet, Jelle; Verguts, Tom; Siugzdaite, Roma

    2018-04-26

    Preparing for a mentally demanding task calls upon cognitive and motivational resources. The underlying neural implementation of these mechanisms is receiving growing attention because of its implications for professional, social, and medical contexts. While several fMRI studies converge in assigning a crucial role to a cortico-subcortical network including Anterior Cigulate Cortex (ACC) and striatum, the involvement of Dorsolateral Prefrontal Cortex (DLPFC) during mental effort anticipation has yet to be replicated. This study was designed to target DLPFC contribution to anticipation of a difficult task using functional Near Infrared Spectroscopy (fNIRS), as a more cost-effective tool measuring cortical hemodynamics. We adapted a validated mental effort task, where participants performed easy and difficult mental calculation, and measured DLPFC activity during the anticipation phase. As hypothesized, DLPFC activity increased during anticipation of a hard task as compared to an easy task. Besides replicating previous fMRI work, these results establish fNIRS as an effective tool to investigate cortical contributions to anticipation of effortful behavior. This is especially useful if one requires testing large samples (e.g., to target individual differences), populations with contraindication for functional MRI (e.g., infants or patients with metal implants), or subjects in more naturalistic environments (e.g., work or sport). Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

  8. Neural signal during immediate reward anticipation in schizophrenia: Relationship to real-world motivation and function

    Subramaniam, Karuna; Hooker, Christine I.; Biagianti, Bruno; Fisher, Melissa; Nagarajan, Srikantan; Vinogradov, Sophia

    2015-01-01

    Amotivation in schizophrenia is a central predictor of poor functioning, and is thought to occur due to deficits in anticipating future rewards, suggesting that impairments in anticipating pleasure can contribute to functional disability in schizophrenia. In healthy comparison (HC) participants, reward anticipation is associated with activity in frontal–striatal networks. By contrast, schizophrenia (SZ) participants show hypoactivation within these frontal–striatal networks during this motivated anticipatory brain state. Here, we examined neural activation in SZ and HC participants during the anticipatory phase of stimuli that predicted immediate upcoming reward and punishment, and during the feedback/outcome phase, in relation to trait measures of hedonic pleasure and real-world functional capacity. SZ patients showed hypoactivation in ventral striatum during reward anticipation. Additionally, we found distinct differences between HC and SZ groups in their association between reward-related immediate anticipatory neural activity and their reported experience of pleasure. HC participants recruited reward-related regions in striatum that significantly correlated with subjective consummatory pleasure, while SZ patients revealed activation in attention-related regions, such as the IPL, which correlated with consummatory pleasure and functional capacity. These findings may suggest that SZ patients activate compensatory attention processes during anticipation of immediate upcoming rewards, which likely contribute to their functional capacity in daily life. PMID:26413478

  9. Convergence of EEG and fMRI measures of reward anticipation.

    Gorka, Stephanie M; Phan, K Luan; Shankman, Stewart A

    2015-12-01

    Deficits in reward anticipation are putative mechanisms for multiple psychopathologies. Research indicates that these deficits are characterized by reduced left (relative to right) frontal electroencephalogram (EEG) activity and blood oxygenation level-dependent (BOLD) signal abnormalities in mesolimbic and prefrontal neural regions during reward anticipation. Although it is often assumed that these two measures capture similar mechanisms, no study to our knowledge has directly examined the convergence between frontal EEG alpha asymmetry and functional magnetic resonance imaging (fMRI) during reward anticipation in the same sample. Therefore, the aim of the current study was to investigate if and where in the brain frontal EEG alpha asymmetry and fMRI measures were correlated in a sample of 40 adults. All participants completed two analogous reward anticipation tasks--once during EEG data collection and the other during fMRI data collection. Results indicated that the two measures do converge and that during reward anticipation, increased relative left frontal activity is associated with increased left anterior cingulate cortex (ACC)/medial prefrontal cortex (mPFC) and left orbitofrontal cortex (OFC) activation. This suggests that the two measures may similarly capture PFC functioning, which is noteworthy given the role of these regions in reward processing and the pathophysiology of disorders such as depression and schizophrenia. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. Neural Activation during Anticipation of Near Pain-Threshold Stimulation among the Pain-Fearful.

    Yang, Zhou; Jackson, Todd; Huang, Chengzhi

    2016-01-01

    Fear of pain (FOP) can increase risk for chronic pain and disability but little is known about corresponding neural responses in anticipation of potential pain. In this study, more (10 women, 6 men) and less (7 women, 6 men) pain-fearful groups underwent whole-brain functional magnetic resonance imaging (fMRI) during anticipation of near pain-threshold stimulation. Groups did not differ in the proportion of stimuli judged to be painful but pain-fearful participants reported significantly more state fear prior to stimulus exposure. Within the entire sample, stronger activation was found in several pain perception regions (e.g., bilateral insula, midcingulate cortex (MCC), thalamus, superior frontal gyrus) and visual areas linked to decoding stimulus valences (inferior orbital cortex) during anticipation of "painful" stimuli. Between groups and correlation analyses indicated pain-fearful participants experienced comparatively more activity in regions implicated in evaluating potential threats and processing negative emotions during anticipation (i.e., MCC, mid occipital cortex, superior temporal pole), though group differences were not apparent in most so-called "pain matrix" regions. In sum, trait- and task-based FOP is associated with enhanced responsiveness in regions involved in threat processing and negative affect during anticipation of potentially painful stimulation.

  11. Neural signal during immediate reward anticipation in schizophrenia: Relationship to real-world motivation and function

    Karuna Subramaniam

    2015-01-01

    Full Text Available Amotivation in schizophrenia is a central predictor of poor functioning, and is thought to occur due to deficits in anticipating future rewards, suggesting that impairments in anticipating pleasure can contribute to functional disability in schizophrenia. In healthy comparison (HC participants, reward anticipation is associated with activity in frontal–striatal networks. By contrast, schizophrenia (SZ participants show hypoactivation within these frontal–striatal networks during this motivated anticipatory brain state. Here, we examined neural activation in SZ and HC participants during the anticipatory phase of stimuli that predicted immediate upcoming reward and punishment, and during the feedback/outcome phase, in relation to trait measures of hedonic pleasure and real-world functional capacity. SZ patients showed hypoactivation in ventral striatum during reward anticipation. Additionally, we found distinct differences between HC and SZ groups in their association between reward-related immediate anticipatory neural activity and their reported experience of pleasure. HC participants recruited reward-related regions in striatum that significantly correlated with subjective consummatory pleasure, while SZ patients revealed activation in attention-related regions, such as the IPL, which correlated with consummatory pleasure and functional capacity. These findings may suggest that SZ patients activate compensatory attention processes during anticipation of immediate upcoming rewards, which likely contribute to their functional capacity in daily life.

  12. A negative relationship between ventral striatal loss anticipation response and impulsivity in borderline personality disorder.

    Herbort, Maike C; Soch, Joram; Wüstenberg, Torsten; Krauel, Kerstin; Pujara, Maia; Koenigs, Michael; Gallinat, Jürgen; Walter, Henrik; Roepke, Stefan; Schott, Björn H

    2016-01-01

    Patients with borderline personality disorder (BPD) frequently exhibit impulsive behavior, and self-reported impulsivity is typically higher in BPD patients when compared to healthy controls. Previous functional neuroimaging studies have suggested a link between impulsivity, the ventral striatal response to reward anticipation, and prediction errors. Here we investigated the striatal neural response to monetary gain and loss anticipation and their relationship with impulsivity in 21 female BPD patients and 23 age-matched female healthy controls using functional magnetic resonance imaging (fMRI). Participants performed a delayed monetary incentive task in which three categories of objects predicted a potential gain, loss, or neutral outcome. Impulsivity was assessed using the Barratt Impulsiveness Scale (BIS-11). Compared to healthy controls, BPD patients exhibited significantly reduced fMRI responses of the ventral striatum/nucleus accumbens (VS/NAcc) to both reward-predicting and loss-predicting cues. BIS-11 scores showed a significant positive correlation with the VS/NAcc reward anticipation responses in healthy controls, and this correlation, while also nominally positive, failed to reach significance in BPD patients. BPD patients, on the other hand, exhibited a significantly negative correlation between ventral striatal loss anticipation responses and BIS-11 scores, whereas this correlation was significantly positive in healthy controls. Our results suggest that patients with BPD show attenuated anticipation responses in the VS/NAcc and, furthermore, that higher impulsivity in BPD patients might be related to impaired prediction of aversive outcomes.

  13. The emergence of urban centres

    Lazaro, Evelyn; Agergaard, Jytte; Larsen, Marianne Nylandsted

    by Tanzanian market liberalizations and its long term effects on private enterprise. The paper is based on a study of four EUCs in Tanzania (Ilula, Igowole, Madizini and Kibaigwa) and seeks to answer three research questions: 1) What economic and spatial trends, including national policies, have formed...... the pathway for rural transformation and early densification towards the emergence of urban centres in Tanzania? 2) What characterize the relationship between value chain dynamics and rural densification? 3) How do migration and investments contribute to the consolidation of EUCs as places of attraction...

  14. Centre for nuclear engineering University of Toronto annual report 1984

    1984-12-01

    The annual report of the Centre for Nuclear Engineering, University of Toronto covers the following subjects: message from the Dean; Chairman's message; origins of the centre; formation of the centre; new nuclear appointments; and activities of the centre, 1984

  15. Centres for Leadership: a strategy for academic integration.

    King, Gillian; Parker, Kathryn; Peacocke, Sean; Curran, C J; McPherson, Amy C; Chau, Tom; Widgett, Elaine; Fehlings, Darcy; Milo-Manson, Golda

    2017-05-15

    Purpose The purpose of this paper is to describe how an Academic Health Science Centre, providing pediatric rehabilitation services, research, and education, developed a Centres for Leadership (CfL) initiative to integrate its academic functions and embrace the goal of being a learning organization. Design/methodology/approach Historical documents, tracked output information, and staff members' insights were used to describe the ten-year evolution of the initiative, its benefits, and transformational learnings for the organization. Findings The evolutions concerned development of a series of CfLs, and changes over time in leadership and management structure, as well as in operations and targeted activities. Benefits included enhanced clinician engagement in research, practice-based research, and impacts on clinical practice. Transformational learnings concerned the importance of supporting stakeholder engagement, fostering a spirit of inquiry, and fostering leaderful practice. These learnings contributed to three related emergent outcomes reflecting "way stations" on the journey to enhanced evidence-informed decision making and clinical excellence: enhancements in authentic partnerships, greater innovation capacity, and greater understanding and actualization of leadership values. Practical implications Practical information is provided for other organizations interested in understanding how this initiative evolved, its tangible value, and its wider benefits for organizational collaboration, innovation, and leadership values. Challenges encountered and main messages for other organizations are also considered. Originality/value A strategy map is used to present the structures, processes, and outcomes arising from the initiative, with the goal of informing the operations of other organizations desiring to be learning organizations.

  16. On the origins of anticipation as an evolutionary framework: functional systems perspective

    Kurismaa, Andres

    2015-08-01

    This paper discusses the problem of anticipation from an evolutionary and systems-theoretical perspective, developed in the context of Russian/Soviet evolutionary biological and neurophysiological schools in the early and mid-twentieth century. On this background, an outline is given of the epigenetic interpretation of anticipatory capacities formulated and substantiated by the eminent Russian neurophysiologist academician Peter K. Anokhin in the framework of functional systems theory. It is considered that several key positions of this theory are well confirmed by recent evidence on anticipation as an evolutionarily basic adaptive capacity, possibly inherent to the organization of life. In the field of neuroscience, the theory of functional systems may potentially facilitate future studies at the intersection of learning, development and evolution by representing an integrative approach to the problem of anticipation.

  17. Event-related EEG responses to anticipation and delivery of monetary and social reward.

    Flores, Amanda; Münte, Thomas F; Doñamayor, Nuria

    2015-07-01

    Monetary and a social incentive delay tasks were used to characterize reward anticipation and delivery with electroencephalography. During reward anticipation, N1, P2 and P3 components were modulated by both prospective reward value and incentive type (monetary or social), suggesting distinctive allocation of attentional and motivational resources depending not only on whether rewards or non-rewards were cued, but also on the monetary and social nature of the prospective outcomes. In the delivery phase, P2, FRN and P3 components were also modulated by levels of reward value and incentive type, illustrating how distinctive affective and cognitive processes were attached to the different outcomes. Our findings imply that neural processing of both reward anticipation and delivery can be specific to incentive type, which might have implications for basic as well as translational research. These results are discussed in the light of previous electrophysiological and neuroimaging work using similar tasks. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. Achievement as Gift and Prestige: Formulating Anticipated Emotion of Others as New Determinant of Consumer Motivation

    Bilson Simamora

    2016-06-01

    Full Text Available Emotion is central component of consumer behavior. This concept, that is borrowed from psychology, is now widely and applied studied in marketing. Two major approaches used by marketing researchers are, first, behavior causes emotions and second, emotions cause behavior. In the second approach, marketing researchers study anticipated emotions of the actors and their consequences on the actors’ behavior. The interesting question, how is anticipated emotion of others on the actor’s behavior? This study is purposed to answer that question. The author studies potential emotions of others that accompany future individuals’ achievement when achievement is considered as gift to significant others or prestige source for the individuals. In doing so, the author develops anticipated emotion of others concept, conceptual model, and related propositions. Discussion, direction for further research, and the contributions of the study to the academic and practical worlds are also presented.

  19. An effect from anticipation also in hereditary nonpolyposis colorectal cancer families without identified mutations

    Timshel, Susanne; Therkildsen, Christina; Bendahl, Pär-Ola

    2009-01-01

    Optimal prevention of hereditary cancer is central and requires initiation of surveillance programmes and/or prophylactic measures at a safe age. Anticipation, expressed as an earlier age at onset in successive generations, has been demonstrated in hereditary nonpolyposis colorectal cancer (HNPCC......). We specifically addressed anticipation in phenotypic HNPCC families without disease-predisposing mismatch repair (MMR) defects since risk estimates and age at onset are particularly difficult to determine in this cohort. The national Danish HNPCC register was used to identify families who fulfilled...... the Amsterdam criteria for HNPCC and showed normal MMR function and/or lack of disease-predisposing MMR gene mutation. In total, 319 cancers from 212 parent-child pairs in 99 families were identified. A paired t-test and a bivariate statistical model were used to assess anticipation. Both methods demonstrated...

  20. Best-estimate methodology for analysis of anticipated transients without scram in pressurized water reactors

    Rebollo, L.

    1993-01-01

    Union Fenosa, a utility company in Spain, has performed research on pressurized water reactor (PWR) safety with respect to the development of a best-estimate methodology for the analysis of anticipated transients without scram (ATWS), i.e., those anticipated transients for which failure of the reactor protection system is postulated. A scientific and technical approach is adopted with respect to the ATWS phenomenon as it affects a PWR, specifically the Zorita nuclear power plant, a single-loop Westinghouse-designed PWR in Spain. In this respect, an ATWS sequence analysis methodology based on published codes that is generically applicable to any PWR is proposed, which covers all the anticipated phenomena and defines the applicable acceptance criteria. The areas contemplated are cell neutron analysis, core thermal hydraulics, and plant dynamics, which are developed, qualified, and plant dynamics, which are developed, qualified, and validated by comparison with reference calculations and measurements obtained from integral or separate-effects tests

  1. Bayesian Modeling for Genetic Anticipation in Presence of Mutational Heterogeneity: A Case Study in Lynch Syndrome

    Boonstra, Philip S; Mukherjee, Bhramar; Taylor, Jeremy M G

    2011-01-01

    Summary Genetic anticipation, described by earlier age of onset (AOO) and more aggressive symptoms in successive generations, is a phenomenon noted in certain hereditary diseases. Its extent may vary between families and/or between mutation subtypes known to be associated with the disease phenotype....... In this article, we posit a Bayesian approach to infer genetic anticipation under flexible random effects models for censored data that capture the effect of successive generations on AOO. Primary interest lies in the random effects. Misspecifying the distribution of random effects may result in incorrect...... to cause hereditary nonpolyposis colorectal cancer, also called Lynch syndrome (LS). We find evidence for a decrease in AOO between generations in this article. Our model predicts family-level anticipation effects that are potentially useful in genetic counseling clinics for high-risk families....

  2. PWR and BWR anticipated and abnormal plant transient research sponsored by the US Nuclear Regulatory Commission

    Beckner, W.D.; Sullivan, L.H.

    1984-01-01

    This chapter reviews the regulatory activities of the US NRC since the realization that anticipated transients with multiple failures (including operator actions) are the major contributors to risk from reactor operations and that the low probability design basis accidents (DBA) are relatively small contributors to risk. The Three Mile Island-2 accident demonstrated that anticipated transients, combined with multiple equipment and/or operator failures, can result in significant core damage. Topics considered include research in direct response to Three Mile Island-2, research in response to specific safety issues, and research to improve the overall understanding of transients (experimental facilities, computer codes). It is concluded that the US NRC has made significant progress in improving its ability to analyze and evaluate abnormal and anticipated transients

  3. Neurobiological underpinnings of reward anticipation and outcome evaluation in gambling disorder

    Linnet, Jakob

    2014-01-01

    Gambling disorder is characterized by persistent and recurrent maladaptive gambling behavior, which leads to clinically significant impairment or distress. The disorder is associated with dysfunctions in the dopamine system. The dopamine system codes reward anticipation and outcome evaluation....... Reward anticipation refers to dopaminergic activation prior to reward, while outcome evaluation refers to dopaminergic activation after reward. This article reviews evidence of dopaminergic dysfunctions in reward anticipation and outcome evaluation in gambling disorder from two vantage points: a model...... of reward prediction and reward prediction error by Wolfram Schultz et al. and a model of “wanting” and “liking” by Terry E. Robinson and Kent C. Berridge. Both models offer important insights on the study of dopaminergic dysfunctions in addiction, and implications for the study of dopaminergic dysfunctions...

  4. Functional MRI reveals expert-novice differences during sport-related anticipation.

    Wright, Michael J; Bishop, Daniel T; Jackson, Robin C; Abernethy, Bruce

    2010-01-27

    We examined the effect of expertise on cortical activation during sports anticipation using functional MRI. In experiment 1, recreational players predicted badminton stroke direction and the pattern of active clusters was consistent with a proposed perception-of-action network. This pattern was not replicated in a stimulus-matched, action-unrelated control task. In experiment 2, players of three different skill levels anticipated stroke direction from clips occluded either 160 ms before or 80 ms after racquet-shuttle contact. Early-occluded sequences produced more activation than late-occluded sequences overall, in most cortical regions of interest, but experts showed an additional enhancement in medial, dorsolateral and ventrolateral frontal cortex. Anticipation in open-skill sports engages cortical areas integral to observing and understanding others' actions; such activity is enhanced in experts.

  5. College students' electronic victimization in friendships and dating relationships: anticipated distress and associations with risky behaviors.

    Bennett, Diana C; Guran, Elyse L; Ramos, Michelle C; Margolin, Gayla

    2011-01-01

    This study investigated college students' reports of electronic victimization in friendships and dating relationships. We examined 22 items representing four categories of electronic victimization: hostility, humiliation, exclusion, and intrusiveness. Nearly all participants (92%) reported some electronic victimization in the past year, with males reporting more victimization and females anticipating more distress. Both females and males anticipated more distress from electronic victimization in dating relationships than friendships. More actual experience with electronic victimization related to lower anticipated distress. Electronic victimization was associated with females' alcohol use, even after controlling for other victimization experiences. Discussion focuses on the contextualized nature of electronic victimization, and on the importance of understanding what makes electronic victimization highly distressing for some individuals.

  6. Perceptual training effects on anticipation of direct and deceptive 7-m throws in handball.

    Alsharji, Khaled E; Wade, Michael G

    2016-01-01

    We examined the effectiveness of perceptual training on the performance of handball goalkeepers when anticipating the direction of both direct and deceptive 7-m throws. Skilled goalkeepers were assigned equally to three matched-ability groups based on their pre-test performance: a perceptual training group (n = 14) received video-based perceptual training, a placebo training group (n = 14) received video-based regular training and a control group received no training. Participants in the perceptual training group significantly improved their performance compared to both placebo and control groups; however, anticipation of deceptive throws improved less than for direct throws. The results confirm that although anticipating deception in handball is a challenging task for goalkeepers, task-specific perceptual training can minimise its effect and improve performance.

  7. Moral Identity Predicts Doping Likelihood via Moral Disengagement and Anticipated Guilt.

    Kavussanu, Maria; Ring, Christopher

    2017-08-01

    In this study, we integrated elements of social cognitive theory of moral thought and action and the social cognitive model of moral identity to better understand doping likelihood in athletes. Participants (N = 398) recruited from a variety of team sports completed measures of moral identity, moral disengagement, anticipated guilt, and doping likelihood. Moral identity predicted doping likelihood indirectly via moral disengagement and anticipated guilt. Anticipated guilt about potential doping mediated the relationship between moral disengagement and doping likelihood. Our findings provide novel evidence to suggest that athletes, who feel that being a moral person is central to their self-concept, are less likely to use banned substances due to their lower tendency to morally disengage and the more intense feelings of guilt they expect to experience for using banned substances.

  8. Analysis of Employee Benefits

    Burešová, Lenka

    2013-01-01

    The target of this bachelor thesis is to analyze employee benefits from the perspective of employees and to employers suggest possible ideas to improve their provision. The work is divided into two parts: theoretical and practical. The theoretical part describes the overal remuneration of employees, payroll system and employee benefits. Benefits are included in the remuneration system, broken and some of them are defined. The practical part presents a survey among employees in the Czech Repub...

  9. The new AMS control centre

    Anaïs Schaeffer

    2011-01-01

    Construction work for the future AMS control room began in November 2010 and should be finished this June. The new building, which will have been completed in record time thanks to the professionalism of the project team, will soon be ready to receive the initial data from the AMS experiment.     Luigi Scibile and Michael Poehler, from the GS department, at the AMS control centre construction site.   The Alpha Magnetic Spectrometer (AMS) is due to wing its way towards the International Space Station (ISS) on board the shuttle Discovery in April. Mainly intended for research on antimatter and dark matter, the data collected by AMS will be sent to Houston in the United States and then directly to CERN’s new Building 946. Construction work for the AMS control centre building on the Route Gentner at CERN’s Prévessin site started in November 2010 and must be completed in time to receive the first data from the spectrometer in June. “It normall...

  10. Neural response to reward anticipation in those with depression with and without panic disorder.

    Gorka, Stephanie M; Huggins, Ashley A; Fitzgerald, Daniel A; Nelson, Brady D; Phan, K Luan; Shankman, Stewart A

    2014-08-01

    One of the hallmark features of major depressive disorder (MDD) is reduced reward anticipation. There have been mixed findings in the literature as to whether reward anticipation deficits in MDD are related to diminished mesolimbic activation and/or enhanced dorsal anterior cingulate activation (dACC). One of the reasons for these mixed findings is that these studies have typically not addressed the role of comorbid anxiety, a class of disorders which frequently co-occur with depression and have a common neurobiology. The aim of the current study was to examine group differences in neural responses to reward anticipation in 40 adults with either: (1) current MDD with no lifetime diagnosis of an anxiety disorder (MDD-only), (2) current MDD with comorbid panic disorder (MDD-PD), or (3) no lifetime diagnosis of psychopathology. All participants completed a passive slot machine task during a functional magnetic resonance imaging (fMRI) scan. Analyses indicated that there were no group differences in activation of mesolimbic reward regions; however, the MDD-only group exhibited greater dACC activation during the anticipation of rewards compared with the healthy controls and the comorbid MDD-PD group (who did not differ from each other). The sample size was small which limits generalizability. These findings provide preliminary support for the role of hyperactive dACC functioning in reduced reward anticipation in MDD. They also indicate that comorbid anxiety may alter the association between MDD and neural responding to reward anticipation. Copyright © 2014 Elsevier B.V. All rights reserved.

  11. Novelty Seeking, Harm Avoidance, and Cerebral Responses to Conflict Anticipation: An Exploratory Study.

    Hu, Jianping; Hu, Sien; Maisano, Julianna R; Chao, Herta H; Zhang, Sheng; Li, Chiang-Shan R

    2016-01-01

    Proactive control allows us to maneuver a changing environment and individuals are distinct in how they anticipate and approach such changes. Here, we examined how individual differences in personality traits influence cerebral responses to conflict anticipation, a critical process of proactive control. We explored this issue in an fMRI study of the stop signal task, in which the probability of stop signal - p(Stop) - was computed trial by trial with a Bayesian model. Higher p(Stop) is associated with prolonged go trial reaction time, indicating conflict anticipation and proactive control of motor response. Regional brain activations to conflict anticipation were correlated to novelty seeking (NS), harm avoidance (HA), reward dependence, as assessed by the Tridimensional Personality Questionnaire, with age and gender as covariates, in a whole-brain linear regression. Results showed that increased anticipation of the stop signal is associated with activations in the bilateral inferior parietal lobules (IPL), right lateral orbitofrontal cortex (lOFC), middle frontal gyrus (MFG), anterior pre-supplementary motor area (pre-SMA), and bilateral thalamus, with men showing greater activation in the IPL than women. NS correlated negatively to activity in the anterior pre-SMA, right IPL, and MFG/lOFC, and HA correlated negatively to activity in the thalamus during conflict anticipation. In addition, the negative association between NS and MFG/lOFC activity was significant in men but not in women. Thus, NS and HA traits are associated with reduced mobilization of cognitive control circuits when enhanced behavioral control is necessary. The findings from this exploratory study characterize the influence of NS and HA on proactive control and provide preliminary evidence for gender differences in these associations.

  12. Neural alterations of fronto-striatal circuitry during reward anticipation in euthymic bipolar disorder.

    Schreiter, S; Spengler, S; Willert, A; Mohnke, S; Herold, D; Erk, S; Romanczuk-Seiferth, N; Quinlivan, E; Hindi-Attar, C; Banzhaf, C; Wackerhagen, C; Romund, L; Garbusow, M; Stamm, T; Heinz, A; Walter, H; Bermpohl, F

    2016-11-01

    Bipolar disorder (BD), with the hallmark symptoms of elevated and depressed mood, is thought to be characterized by underlying alterations in reward-processing networks. However, to date the neural circuitry underlying abnormal responses during reward processing in BD remains largely unexplored. The aim of this study was to investigate whether euthymic BD is characterized by aberrant ventral striatal (VS) activation patterns and altered connectivity with the prefrontal cortex in response to monetary gains and losses. During functional magnetic resonance imaging 20 euthymic BD patients and 20 age-, gender- and intelligence quotient-matched healthy controls completed a monetary incentive delay paradigm, to examine neural processing of reward and loss anticipation. A priori defined regions of interest (ROIs) included the VS and the anterior prefrontal cortex (aPFC). Psychophysiological interactions (PPIs) between these ROIs were estimated and tested for group differences for reward and loss anticipation separately. BD participants, relative to healthy controls, displayed decreased activation selectively in the left and right VS during anticipation of reward, but not during loss anticipation. PPI analyses showed decreased functional connectivity between the left VS and aPFC in BD patients compared with healthy controls during reward anticipation. This is the first study showing decreased VS activity and aberrant connectivity in the reward-processing circuitry in euthymic, medicated BD patients during reward anticipation. Our findings contrast with research supporting a reward hypersensitivity model of BD, and add to the body of literature suggesting that blunted activation of reward processing circuits may be a vulnerability factor for mood disorders.

  13. Effects of Spike Anticipation on the Spiking Dynamics of Neural Networks.

    de Santos-Sierra, Daniel; Sanchez-Jimenez, Abel; Garcia-Vellisca, Mariano A; Navas, Adrian; Villacorta-Atienza, Jose A

    2015-01-01

    Synchronization is one of the central phenomena involved in information processing in living systems. It is known that the nervous system requires the coordinated activity of both local and distant neural populations. Such an interplay allows to merge different information modalities in a whole processing supporting high-level mental skills as understanding, memory, abstraction, etc. Though, the biological processes underlying synchronization in the brain are not fully understood there have been reported a variety of mechanisms supporting different types of synchronization both at theoretical and experimental level. One of the more intriguing of these phenomena is the anticipating synchronization, which has been recently reported in a pair of unidirectionally coupled artificial neurons under simple conditions (Pyragiene and Pyragas, 2013), where the slave neuron is able to anticipate in time the behavior of the master one. In this paper, we explore the effect of spike anticipation over the information processing performed by a neural network at functional and structural level. We show that the introduction of intermediary neurons in the network enhances spike anticipation and analyse how these variations in spike anticipation can significantly change the firing regime of the neural network according to its functional and structural properties. In addition we show that the interspike interval (ISI), one of the main features of the neural response associated with the information coding, can be closely related to spike anticipation by each spike, and how synaptic plasticity can be modulated through that relationship. This study has been performed through numerical simulation of a coupled system of Hindmarsh-Rose neurons.

  14. Dissociable Fronto-Operculum-Insula Control Signals for Anticipation and Detection of Inhibitory Sensory Cue.

    Cai, Weidong; Chen, Tianwen; Ide, Jaime S; Li, Chiang-Shan R; Menon, Vinod

    2017-08-01

    The ability to anticipate and detect behaviorally salient stimuli is important for virtually all adaptive behaviors, including inhibitory control that requires the withholding of prepotent responses when instructed by external cues. Although right fronto-operculum-insula (FOI), encompassing the anterior insular cortex (rAI) and inferior frontal cortex (rIFC), involvement in inhibitory control is well established, little is known about signaling mechanisms underlying their differential roles in detection and anticipation of salient inhibitory cues. Here we use 2 independent functional magnetic resonance imaging data sets to investigate dynamic causal interactions of the rAI and rIFC, with sensory cortex during detection and anticipation of inhibitory cues. Across 2 different experiments involving auditory and visual inhibitory cues, we demonstrate that primary sensory cortex has a stronger causal influence on rAI than on rIFC, suggesting a greater role for the rAI in detection of salient inhibitory cues. Crucially, a Bayesian prediction model of subjective trial-by-trial changes in inhibitory cue anticipation revealed that the strength of causal influences from rIFC to rAI increased significantly on trials in which participants had higher anticipation of inhibitory cues. Together, these results demonstrate the dissociable bottom-up and top-down roles of distinct FOI regions in detection and anticipation of behaviorally salient cues across multiple sensory modalities. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  15. Dissociating the influence of response selection and task anticipation on corticospinal suppression during response preparation.

    Duque, Julie; Labruna, Ludovica; Cazares, Christian; Ivry, Richard B

    2014-12-01

    Motor behavior requires selecting between potential actions. The role of inhibition in response selection has frequently been examined in tasks in which participants are engaged in some advance preparation prior to the presentation of an imperative signal. Under such conditions, inhibition could be related to processes associated with response selection, or to more general inhibitory processes that are engaged in high states of anticipation. In Experiment 1, we manipulated the degree of anticipatory preparation. Participants performed a choice reaction time task that required choosing between a movement of the left or right index finger, and used transcranial magnetic stimulation (TMS) to elicit motor evoked potentials (MEPs) in the left hand agonist. In high anticipation blocks, a non-informative cue (e.g., fixation marker) preceded the imperative; in low anticipation blocks, there was no cue and participants were required to divide their attention between two tasks to further reduce anticipation. MEPs were substantially reduced before the imperative signal in high anticipation blocks. In contrast, in low anticipation blocks, MEPs remained unchanged before the imperative signal but showed a marked suppression right after the onset of the imperative. This effect occurred regardless of whether the imperative had signalled a left or right hand response. After this initial inhibition, left MEPs increased when the left hand was selected and remained suppressed when the right hand was selected. We obtained similar results in Experiment 2 except that the persistent left MEP suppression when the left hand was not selected was attenuated when the alternative response involved a non-homologous effector (right foot). These results indicate that, even in the absence of an anticipatory period, inhibitory mechanisms are engaged during response selection, possibly to prevent the occurrence of premature and inappropriate responses during a competitive selection process. Copyright

  16. Local perceptions of cholera and anticipated vaccine acceptance in Katanga province, Democratic Republic of Congo

    2013-01-01

    Background In regions where access to clean water and the provision of a sanitary infrastructure has not been sustainable, cholera continues to pose an important public health burden. Although oral cholera vaccines (OCV) are effective means to complement classical cholera control efforts, still relatively little is known about their acceptability in targeted communities. Clarification of vaccine acceptability prior to the introduction of a new vaccine provides important information for future policy and planning. Methods In a cross-sectional study in Katanga province, Democratic Republic of Congo (DRC), local perceptions of cholera and anticipated acceptance of an OCV were investigated. A random sample of 360 unaffected adults from a rural town and a remote fishing island was interviewed in 2010. In-depth interviews with a purposive sample of key informants and focus-group discussions provided contextual information. Socio-cultural determinants of anticipated OCV acceptance were assessed with logistic regression. Results Most respondents perceived contaminated water (63%) and food (61%) as main causes of cholera. Vaccines (28%), health education (18%) and the provision of clean water (15%) were considered the most effective measures of cholera control. Anticipated vaccine acceptance reached 97% if an OCV would be provided for free. Cholera-specific knowledge of hygiene and self-help in form of praying for healing were positively associated with anticipated OCV acceptance if costs of USD 5 were assumed. Conversely, respondents who feared negative social implications of cholera were less likely to anticipate acceptance of OCVs. These fears were especially prominent among respondents who generated their income through fishing. With an increase of assumed costs to USD 10.5, fear of financial constraints was negatively associated with anticipated vaccine acceptance as well. Conclusions Results suggest a high motivation to use an OCV as long as it seems affordable. The

  17. Effects of Spike Anticipation on the Spiking Dynamics of Neural Networks

    Daniel ede Santos-Sierra

    2015-11-01

    Full Text Available Synchronization is one of the central phenomena involved in information processing in living systems. It is known that the nervous system requires the coordinated activity of both local and distant neural populations. Such an interplay allows to merge different information modalities in a whole processing supporting high-level mental skills as understanding, memory, abstraction, etc. Though the biological processes underlying synchronization in the brain are not fully understood there have been reported a variety of mechanisms supporting different types of synchronization both at theoretical and experimental level. One of the more intriguing of these phenomena is the anticipating synchronization, which has been recently reported in a pair of unidirectionally coupled artificial neurons under simple conditions cite{Pyragas}, where the slave neuron is able to anticipate in time the behaviour of the master one. In this paper we explore the effect of spike anticipation over the information processing performed by a neural network at functional and structural level. We show that the introduction of intermediary neurons in the network enhances spike anticipation and analyse how these variations in spike anticipation can significantly change the firing regime of the neural network according to its functional and structural properties. In addition we show that the interspike interval (ISI, one of the main features of the neural response associated to the information coding, can be closely related to spike anticipation by each spike, and how synaptic plasticity can be modulated through that relationship. This study has been performed through numerical simulation of a coupled system of Hindmarsh-Rose neurons.

  18. Fear of negative evaluation modulates electrocortical and behavioral responses when anticipating social evaluative feedback

    Melle J.W. Van Der Molen

    2014-01-01

    Full Text Available Cognitive models posit that the fear of negative evaluation (FNE is a hallmark feature of social anxiety. As such, individuals with high FNE may show biased information processing when faced with social evaluation. The aim of the current study was to examine the neural underpinnings of anticipating and processing of social-evaluative feedback, and its correlates with FNE. We used a social judgment paradigm in which female participants (N=31 were asked to indicate whether they believed to be socially accepted or rejected by their peers. Anticipatory attention was indexed by the stimulus preceding negativity (SPN, while the feedback-related negativity and P3 were used to index the processing of social-evaluative feedback. Results provided evidence of an optimism bias in social peer evaluation, as participants more often predicted to be socially accepted than rejected. Participants with high levels of FNE needed more time to provide their judgments about the social-evaluative outcome. While anticipating social-evaluative feedback, SPN amplitudes were larger for anticipated social acceptance than for social rejection feedback. Interestingly, the SPN during anticipated social acceptance was larger in participants with high levels of FNE. None of the feedback-related brain potentials correlated with the FNE. Together, the results provide evidence of biased information processing in individuals with high levels of FNE when anticipating (rather than processing social-evaluative feedback. The delayed response times in high FNE individuals were interpreted to reflect augmented vigilance imposed by the upcoming social evaluative threat. Allegedly, the SPN constitutes a neural marker of this vigilance in females with higher FNE levels, particularly when anticipating social acceptance feedback.

  19. Fear of negative evaluation modulates electrocortical and behavioral responses when anticipating social evaluative feedback

    Van der Molen, Melle J. W.; Poppelaars, Eefje S.; Van Hartingsveldt, Caroline T. A.; Harrewijn, Anita; Gunther Moor, Bregtje; Westenberg, P. Michiel

    2014-01-01

    Cognitive models posit that the fear of negative evaluation (FNE) is a hallmark feature of social anxiety. As such, individuals with high FNE may show biased information processing when faced with social evaluation. The aim of the current study was to examine the neural underpinnings of anticipating and processing social-evaluative feedback, and its correlates with FNE. We used a social judgment paradigm in which female participants (N = 31) were asked to indicate whether they believed to be socially accepted or rejected by their peers. Anticipatory attention was indexed by the stimulus preceding negativity (SPN), while the feedback-related negativity and P3 were used to index the processing of social-evaluative feedback. Results provided evidence of an optimism bias in social peer evaluation, as participants more often predicted to be socially accepted than rejected. Participants with high levels of FNE needed more time to provide their judgments about the social-evaluative outcome. While anticipating social-evaluative feedback, SPN amplitudes were larger for anticipated social acceptance than for social rejection feedback. Interestingly, the SPN during anticipated social acceptance was larger in participants with high levels of FNE. None of the feedback-related brain potentials correlated with the FNE. Together, the results provided evidence of biased information processing in individuals with high levels of FNE when anticipating (rather than processing) social-evaluative feedback. The delayed response times in high FNE individuals were interpreted to reflect augmented vigilance imposed by the upcoming social-evaluative threat. Possibly, the SPN constitutes a neural marker of this vigilance in females with higher FNE levels, particularly when anticipating social acceptance feedback. PMID:24478667

  20. Dissociating the Influence of Response Selection and Task Anticipation on Corticospinal Suppression During Response Preparation

    Duque, Julie; Labruna, Ludovica; Cazares, Christian; Ivry, Richard B.

    2014-01-01

    Motor behavior requires selecting between potential actions. The role of inhibition in response selection has frequently been examined in tasks in which participants are engaged in some advance preparation prior to the presentation of an imperative signal. Under such conditions, inhibition could be related to processes associated with response selection, or to more general inhibitory processes that are engaged in high states of anticipation. In Experiment 1, we manipulated the degree of anticipatory preparation. Participants performed a choice reaction time task that required choosing between a movement of the left or right index finger, and used transcranial magnetic stimulation (TMS) to elicit motor evoked potentials (MEPs) in the left hand agonist. In high anticipation blocks, a non-informative cue (e.g., fixation marker) preceded the imperative; in low anticipation blocks, there was no cue and participants were required to divide their attention between two tasks to further reduce anticipation. MEPs were substantially reduced before the imperative signal in high anticipation blocks. In contrast, in low anticipation blocks, MEPs remained unchanged before the imperative signal but showed a marked suppression right after the onset of the imperative. This effect occurred regardless of whether the imperative had signaled a left or right hand response. After this initial inhibition, left MEPs increased when the left hand was selected and remained suppressed when the right hand was selected. We obtained similar results in Experiment 2 except that the persistent left MEP suppression when the left hand was not selected was attenuated when the alternative response involved a non-homologous effector (right foot). These results indicate that, even in the absence of an anticipatory period, inhibitory mechanisms are engaged during response selection, possibly to prevent the occurrence of premature and inappropriate responses during a competitive selection process. PMID

  1. Learning from a mouse - how adoption of Disney methods could assist development of CANDU control centres

    Davey, E. [Crew Systems Solutions, Deep River, Ontario (Canada)

    2005-07-01

    Many organizations are challenged with the tasks of identifying customer needs and expectations for their products, anticipating future product needs, communicating a future product vision to clients, and designing with today's technology to bring a future vision to successful realization. The design evolution of plant control centres is one aspect of CANDU development that faces such challenges. The Disney Corporation is an example of an organization that has been successful in consistently meeting these challenges for over fifty years; and some of the design practices proven in moviemaking, theme park and resort layout, and vacation experience organization may be helpful and effective when applied in other domains. This paper summarizes the findings from an examination of Disney Corporation design practices, and suggests how some practices could be used to simplify and enhance the design of future CANDU control centres. (author)

  2. Learning from a mouse - how adoption of Disney methods could assist development of CANDU control centres

    Davey, E.

    2005-01-01

    Many organizations are challenged with the tasks of identifying customer needs and expectations for their products, anticipating future product needs, communicating a future product vision to clients, and designing with today's technology to bring a future vision to successful realization. The design evolution of plant control centres is one aspect of CANDU development that faces such challenges. The Disney Corporation is an example of an organization that has been successful in consistently meeting these challenges for over fifty years; and some of the design practices proven in moviemaking, theme park and resort layout, and vacation experience organization may be helpful and effective when applied in other domains. This paper summarizes the findings from an examination of Disney Corporation design practices, and suggests how some practices could be used to simplify and enhance the design of future CANDU control centres. (author)

  3. Transit Benefit Program Data -

    Department of Transportation — This data set contains information about any US government agency participating in the transit benefits program, funding agreements, individual participating Federal...

  4. Socio-cultural determinants of anticipated acceptance of an oral cholera vaccine in Western Kenya

    SUNDARAM, N.; SCHAETTI, C.; CHAIGNAT, C.-L.; HUTUBESSY, R.; NYAMBEDHA, E. O.; MBONGA, L. A.; WEISS, M. G.

    2012-01-01

    SUMMARY Determinants of anticipated acceptance of an oral cholera vaccine (OCV) were studied in urban and rural communities of Western Kenya. An explanatory model interview administered to 379 community residents assessed anticipated vaccine acceptance at various prices from no cost to full-cost recovery, socio-cultural features of cholera and social characteristics. Nearly all (99%) residents indicated willingness to accept a no-cost OCV, 95% at a price of US$ 0?8, 73% at US$ 4?2 and 59% at ...

  5. Control-oriented approaches to anticipating synchronization of chaotic deterministic ratchets

    Xu Shiyun [State Key Lab for Turbulence and Complex Systems, Department of Mechanics and Aerospace Engineering, College of Engineering, Peking University, Beijing 100871 (China)], E-mail: xushiyun@pku.edu.cn; Yang Ying [State Key Lab for Turbulence and Complex Systems, Department of Mechanics and Aerospace Engineering, College of Engineering, Peking University, Beijing 100871 (China)], E-mail: yy@mech.pku.edu.cn; Song Lei [State Key Lab for Turbulence and Complex Systems, Department of Mechanics and Aerospace Engineering, College of Engineering, Peking University, Beijing 100871 (China)

    2009-06-15

    In virtue of techniques derived from nonlinear control system theory, we establish conditions under which one could obtain anticipating synchronization between two periodically driven deterministic ratchets that are able to exhibit directed transport with a finite velocity. Criteria are established in order to guarantee the anticipating synchronization property of such systems as well as characterize phase space dynamics of the ratchet transporting behaviors. These results allow one to predict the chaotic direct transport features of particles on a ratchet potential using a copy of the same system that performs as a slave, which are verified through numerical simulation.

  6. A review of statistical methods for testing genetic anticipation: looking for an answer in Lynch syndrome

    Boonstra, Philip S; Gruber, Stephen B; Raymond, Victoria M

    2010-01-01

    the issue of multiplex ascertainment and its effect on the different methods. We then focus on exploring genetic anticipation in Lynch syndrome and analyze new data on the age of onset in affected parent-child pairs from families seen at the University of Michigan Cancer Genetics clinic with a mutation...... in one of the three main mismatch repair (MMR) genes. In contrast to the clinic-based population, we re-analyze data on a population-based Lynch syndrome cohort, derived from the Danish HNPCC-register. Both datasets indicate evidence of genetic anticipation in Lynch syndrome. We then expand our review...

  7. A promising poison information centre model for Africa

    Carine Marks

    2016-06-01

    Conclusion: A number of benefits might result from such a poisons centre network hub, including: (1 Improved cooperation between countries on poisoning problems; (2 Harmonisation and strengthening of research and surveillance; (3 Common standards and best practices e.g. regulating chemicals, data management, and staff training; and (4 Greater bargaining power to secure resources. Further investigation is needed to identify the most suitable location for the network hub, the activities it should fulfil, and the availability of specialists in poisons information who could become members of the hub.

  8. Unemployment Benefit Exhaustion

    Filges, Trine; Pico Geerdsen, Lars; Knudsen, Anne-Sofie Due

    2015-01-01

    This systematic review studied the impact of exhaustion of unemployment benefits on the exit rate out of unemployment and into employment prior to benefit exhaustion or shortly thereafter. Method: We followed Campbell Collaboration guidelines to prepare this review, and ultimately located 12...

  9. Putting Paid to Benefits

    Stella Hoff; Gerda Jehoel-Gijsbers; J.M. Wildeboer Schut

    2003-01-01

    Original title: De uitkering van de baan. A good deal of time, money and effort is invested in the reintegration of benefit claimants. What is the result? How many recipients of disability, unemployment or social assistance benefit are in principle capable of working but are currently not

  10. Nanocosmetics: benefits and risks

    Shokri, Javad

    2017-01-01

    Summary Various nanomaterials/nanoparticles (NPs) have been used for the development of cosmetic products - a field so-called nanocosmetic formulations. These advanced materials offer some benefits, while their utilization in the cosmetic formulations may be associated with some risks. The main aim of this editorial is to highlight the benefits and risks of the nanomaterials used in the cosmetic products.

  11. Who Benefits from Religion?

    Mochon, Daniel; Norton, Michael I.; Ariely, Dan

    2011-01-01

    Many studies have documented the benefits of religious involvement. Indeed, highly religious people tend to be healthier, live longer, and have higher levels of subjective well-being. While religious involvement offers clear benefits to many, in this paper we explore whether it may also be detrimental to some. Specifically, we examine in detail…

  12. Wellbeing or welfare benefits

    Handlos, Line Neerup; Kristiansen, Maria; Nørredam, Marie Louise

    2016-01-01

    This debate article debunks the myth that migrants are driven primarily by the size of the welfare benefits in the host country, when they decide where to migrate to. We show that instead of welfare benefits, migrants are driven by a desire for safety, wellbeing, social networks and opportunities...

  13. Smart work centres in rural areas

    Lorentzen, Anne Birte

    This paper discusses the establishment of telework centres as an element in local development strategies in rural areas, with a particular view to two new telework centres in region North Denmark. The paper argues that telework centres do not represent an easy solution to problems of local...... development and environmental sustainability, and further, that technology may not even be the most important feature needed to make them function as such....

  14. Elm Farm Organic Research Centre December 2006

    Sanders, Richard; Whiltley, Andrew; Haigh, Zoe; Clarke, Sarah; Hitchings, Roger; O'Brien, Josie

    2006-01-01

    The Organic Research Centre. Elm Farm Research Centre Bulletin with Technical Updates from The Organic Advisory Service is a regular publication from The Organic Research Centre. The current issue covers: Report from 2006 Cirencester Conference; Quest for more home produced organic food; in a world where bread matters; Improving wheat with plenty of parents; Unlocking the secrets of the ancient (cereal varieties); Brain food- a good read; Not to late to protect the future: The organic...

  15. Powering the Future Data Centre

    Zhang, Zhe

    2010-01-01

    of the characteristics of these two power sources: long warm-up stage and low dynamics for fuel cell, and variable terminal voltage for supercapacitors. The motivation for this project was to find ways which can overcome those limitations to integrate fuel cells and supercapcitors to the system with high efficiency......The extended run Uninterruptible Power Supply system (UPSs) which powered by fuel cells and supercapcitors, is a promising solution for future data centre to obtain environmentfriendly energy efficient and cost effective. There are many challenges in power electronic interface circuits, because......: • Optimized design method for dual active bridge (DAB) converter and its derived circuits; • A novel hybrid dc-dc converter and its corresponding optimal design method are proposed; • An improved dual input current-fed DC-DC converter with bidirectional power conversion ability is investigated; • Extend...

  16. Preparation of emergency care centre exercises

    Schnadt, H.; Miska, H.

    2011-01-01

    Setup and operation of emergency care centres (sometimes also addressed as emergency reception centres) are part of emergency response in the environs of nuclear power plants. The preparation of an exercise scenario for such a centre is very demanding on the responsible agency. Therefore, a computer code has been developed which helps to translate the exercise objectives into instructions for figurants which simulate the affected population. These instructions are intended to steer a determined flow of people through the emergency care centre by providing fictitious radiological readings and by injecting the demand for additional actions of response personnel by statements and questions. (orig.)

  17. Perceived and anticipated discrimination in people with mental illness--an interview study.

    Hansson, Lars; Stjernswärd, Sigrid; Svensson, Bengt

    2014-02-01

    Studies on perceived discrimination of people with mental illness are largely lacking. The purpose of the study was to investigate perceived discrimination in a sample of users in contact with mental health services in Sweden. Interviews were conducted with 156 users, asking for perceived and anticipated discrimination during the last 2 years. Background characteristics were also collected. Perceived discrimination was common. Highest frequencies were reported regarding family (54%), avoidance by people who knew about the mental illness (53%) and in making or keeping friends (50%). A majority of those anticipating discrimination regarding job or education seeking, or starting a close relationship did not report having been discriminated in these areas. Previous hospitalizations were associated with discrimination, and age with anticipated discrimination. Public stigma and self-stigma have been reported to have a number of negative consequences for people with mental illness. Discrimination is part of this complex situation and this study showed that this largely affects a number of individual life areas posing an obstacle for social integration. Anticipated discrimination or self-stigma was also prevalent and it is pointed out that this to a great extent is an obstacle on its own without being promoted by actual experiences of discrimination.

  18. An effect from anticipation also in hereditary nonpolyposis colorectal cancer families without identified mutations

    Timshel, Susanne; Therkildsen, Christina; Bendahl, Pär-Ola

    2009-01-01

    the Amsterdam criteria for HNPCC and showed normal MMR function and/or lack of disease-predisposing MMR gene mutation. In total, 319 cancers from 212 parent-child pairs in 99 families were identified. A paired t-test and a bivariate statistical model were used to assess anticipation. Both methods demonstrated...

  19. The Influence of Anticipation of Word Misrecognition on the Likelihood of Stuttering

    Brocklehurst, Paul H.; Lickley, Robin J.; Corley, Martin

    2012-01-01

    This study investigates whether the experience of stuttering can result from the speaker's anticipation of his words being misrecognized. Twelve adults who stutter (AWS) repeated single words into what appeared to be an automatic speech-recognition system. Following each iteration of each word, participants provided a self-rating of whether they…

  20. Initial and sustained brain responses to threat anticipation in blood-injection-injury phobia

    Leonie Brinkmann

    2017-01-01

    Full Text Available Blood-injection-injury (BII phobia differs from other subtypes of specific phobia in that it is associated with elevated disgust-sensitivity as well as specific autonomic and brain responses during processing of phobia-relevant stimuli. To what extent these features play a role already during threat anticipation is unclear. In the current fMRI experiment, 16 female BII phobics and 16 female healthy controls anticipated the presentation of phobia-specific and neutral pictures. On the behavioral level, anxiety dominated the anticipatory period in BII phobics relative to controls, while both anxiety and disgust were elevated during picture presentation. By applying two different models for the analysis of brain responses to anticipation of phobia-specific versus neutral stimuli, we found initial and sustained increases of activation in anterior cingulate cortex (ACC, insula, lateral and medial prefrontal cortex (PFC, thalamus and visual areas, as well as initial activation in the amygdala for BII phobics as compared to healthy controls. These results suggest that BII phobia is characterized by activation of a typical neural defense network during threat anticipation, with anxiety as the predominant emotion.

  1. Differential effects of uncertainty on LPP responses to emotional events during explicit and implicit anticipation.

    Lin, Huiyan; Liang, Jiafeng; Jin, Hua; Zhao, Dongmei

    2018-07-01

    Previous studies have investigated whether uncertainty influences neural responses to emotional events. The findings of such studies, particularly with respect to event-related potentials (ERPs), have been controversial due to several factors, such as the stimuli that serve as cues and the emotional content of the events. However, it is still unknown whether the effects of uncertainty on ERP responses to emotional events are influenced by anticipation patterns (e.g., explicit or implicit anticipation). To address this issue, participants in the present study were presented with anticipatory cues and then emotional (negative and neutral) pictures. The cues either did or did not signify the emotional content of the upcoming picture. In the inter-stimulus intervals between cues and pictures, participants were asked to estimate the expected probability of the occurrence of a specific emotional category of the subsequent picture based on a scale in the explicit anticipation condition, while in the implicit condition, participants were asked to indicate, using a number on a scale, which color was different from the others. The results revealed that in the explicit condition, uncertainty increased late positive potential (LPP) responses, particularly for negative pictures, whereas LPP responses were larger for certain negative pictures than for uncertain negative pictures in the implicit condition. The findings in the present study suggest that the anticipation pattern influences the effects of uncertainty when evaluation of negative events. Copyright © 2018 Elsevier B.V. All rights reserved.

  2. Age associations with neural processing of reward anticipation in adolescents with bipolar disorders

    Urošević, Snežana; Luciana, Monica; Jensen, Jonathan B.; Youngstrom, Eric A.; Thomas, Kathleen M.

    2016-01-01

    Reward/behavioral approach system hypersensitivity is implicated in bipolar disorders (BD) and in normative development during adolescence. Pediatric onset of BD is associated with a more severe illness course. However, little is known about neural processing of rewards in adolescents with BD or developmental (i.e., age) associations with activation of these neural systems. The present study aims to address this knowledge gap. The present sample included 21 adolescents with BD and 26 healthy adolescents, ages 13 to 19. Participants completed a functional magnetic resonance imaging (fMRI) protocol using the Monetary Incentive Delay (MID) task. Behavioral performance was similar between groups. Group differences in BOLD activation during target anticipation and feedback anticipation periods of the task were examined using whole-brain analyses, as were group differences in age effects. During both target anticipation and feedback anticipation, adolescents with BD, compared to adolescents without psychopathology, exhibited decreased engagement of frontal regions involved in cognitive control (i.e., dorsolateral prefrontal cortex). Healthy adolescents exhibited age-related decreases, while adolescents with BD exhibited age-related increases, in activity of other cognitive control frontal areas (i.e., right inferior frontal gyrus), suggesting altered development in the BD group. Longitudinal research is needed to examine potentially abnormal development of cognitive control during reward pursuit in adolescent BD and whether early therapeutic interventions can prevent these potential deviations from normative development. PMID:27114896

  3. Differential mesolimbic and prefrontal alterations during reward anticipation and consummation in positive and negative schizotypy.

    Yan, Chao; Wang, Yi; Su, Li; Xu, Ting; Yin, Da-Zhi; Fan, Ming-Xia; Deng, Ci-Ping; Wang, Zhao-Xin; Lui, Simon S Y; Cheung, Eric F C; Chan, Raymond C K

    2016-08-30

    Schizotypy is associated with anhedonia. However, previous findings on the neural substrates of anhedonia in schizotypy are mixed. In the present study, we measured the neural substrates associated with reward anticipation and consummation in positive and negative schizotypy using functional MRI. The Monetary Incentive Delay task was administered to 33 individuals with schizotypy (18 positive schizotypy (PS),15 negative schizotypy (NS)) and 22 healthy controls. Comparison between schizotypy individuals and controls were performed using two-sample T tests for contrast images involving gain versus non-gain anticipation condition and gain versus non-gain consummation condition. Multiple comparisons were corrected using Monte Carlo Simulation correction of panticipation or consummation. However, during the consummatory phase, NS individuals rather than PS individuals showed diminished left amygdala and left putamen activity compared with controls. We observed significantly weaker activation at the left ventral striatum during gain anticipation in NS individuals compared with controls. PS individuals, however, exhibited enhanced right ventral lateral prefrontal activity. These findings suggest that different dimensions of schizotypy may be underlied by different neural dysfunctions in reward anticipation and consummation. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  4. Perceptual Training Methods Compared: The Relative Efficacy of Different Approaches to Enhancing Sport-Specific Anticipation

    Abernethy, Bruce; Schorer, Jorg; Jackson, Robin C.; Hagemann, Norbert

    2012-01-01

    The comparative efficacy of different perceptual training approaches for the improvement of anticipation was examined using a goalkeeping task from European handball that required the rapid prediction of shot direction. Novice participants (N = 60) were assigned equally to four different training groups and two different control groups (a placebo…

  5. Effects of increasing and decreasing physiological arousal on anticipation timing performance during competition and practice.

    Duncan, Michael J; Smith, Mike; Bryant, Elizabeth; Eyre, Emma; Cook, Kathryn; Hankey, Joanne; Tallis, Jason; Clarke, Neil; Jones, Marc V

    2016-01-01

    The aim of this study was to investigate if the effects of changes in physiological arousal on timing performance can be accurately predicted by the catastrophe model. Eighteen young adults (8 males, 10 females) volunteered to participate in the study following ethical approval. After familiarisation, coincidence anticipation was measured using the Bassin Anticipation Timer under four incremental exercise conditions: Increasing exercise intensity and low cognitive anxiety, increasing exercise intensity and high cognitive anxiety, decreasing exercise intensity and low cognitive anxiety and decreasing exercise intensity and high cognitive anxiety. Incremental exercise was performed on a treadmill at intensities of 30%, 50%, 70% and 90% heart rate reserve (HRR) respectively. Ratings of cognitive anxiety were taken at each intensity using the Mental Readiness Form 3 (MRF3) followed by performance of coincidence anticipation trials at speeds of 3 and 8 mph. Results indicated significant condition × intensity interactions for absolute error (AE; p = .0001) and MRF cognitive anxiety intensity scores (p = .05). Post hoc analysis indicated that there were no statistically significant differences in AE across exercise intensities in low-cognitive anxiety conditions. In high-cognitive anxiety conditions, timing performance AE was significantly poorer and cognitive anxiety higher at 90% HRR, compared to the other exercise intensities. There was no difference in timing responses at 90% HRR during competitive trials, irrespective of whether exercise intensity was increasing or decreasing. This study suggests that anticipation timing performance is negatively affected when physiological arousal and cognitive anxiety are high.

  6. Anticipation in Real-world Scenes: The Role of Visual Context and Visual Memory

    Coco, Moreno I.; Keller, Frank; Malcolm, George L.

    2016-01-01

    The human sentence processor is able to make rapid predictions about upcoming linguistic input. For example, upon hearing the verb eat, anticipatory eye-movements are launched toward edible objects in a visual scene (Altmann & Kamide, 1999). However, the cognitive mechanisms that underlie anticipation remain to be elucidated in ecologically…

  7. A Genetic Polymorphism of the Endogenous Opioid Dynorphin Modulates Monetary Reward Anticipation in the Corticostriatal Loop

    Votinov, Mikhail; Pripfl, Juergen; Windischberger, Christian; Kalcher, Klaudius; Zimprich, Alexander; Zimprich, Fritz; Moser, Ewald

    2014-01-01

    The dynorphin/κ-opioid receptor (KOP-R) system has been shown to play a role in different types of behavior regulation, including reward-related behavior and drug craving. It has been shown that alleles with 3 or 4 repeats (HH genotype) of the variable nucleotide tandem repeat (68-bp VNTR) functional polymorphism of the prodynorphin (PDYN) gene are associated with higher levels of dynorphin peptides than alleles with 1 or 2 repeats (LL genotype). We used fMRI on N = 71 prescreened healthy participants to investigate the effect of this polymorphism on cerebral activation in the limbic-corticostriatal loop during reward anticipation. Individuals with the HH genotype showed higher activation than those with the LL genotype in the medial orbitofrontal cortex (mOFC) when anticipating a possible monetary reward. In addition, the HH genotype showed stronger functional coupling (as assessed by effective connectivity analyses) of mOFC with VMPFC, subgenual anterior cingulate cortex, and ventral striatum during reward anticipation. This hints at a larger sensitivity for upcoming rewards in individuals with the HH genotype, resulting in a higher motivation to attain these rewards. These findings provide first evidence in humans that the PDYN polymorphism modulates neural processes associated with the anticipation of rewards, which ultimately may help to explain differences between genotypes with respect to addiction and drug abuse. PMID:24587148

  8. The effect of a new communication template on anticipated willingness to initiate or resume allergen immunotherapy

    Calderon, Moises A; Cox, Linda; Casale, Thomas B

    2015-01-01

    to validate the new communication template and to assess its impact on anticipated willingness to initiate or resume allergen immunotherapy. RESULTS: We surveyed a total of 261 patients (France: 57; Germany: 51; Spain: 52; USA: 51; Russia: 50), comprising 127 "early abandoners" and 134 "non...

  9. Exploring potential social influences on brain potentials during anticipation of tactile stimulation.

    Shen, Guannan; Saby, Joni N; Drew, Ashley R; Marshall, Peter J

    2017-03-15

    This study explored interpersonal influences on electrophysiological responses during the anticipation of tactile stimulation. It is well-known that broad, negative-going potentials are present in the event-related potential (ERP) between a forewarning cue and a tactile stimulus. It has also been shown that the alpha-range mu rhythm shows a lateralized desynchronization over central electrode sites during anticipation of tactile stimulation of the hand. The current study used a tactile discrimination task in which a visual cue signaled that an upcoming stimulus would either be delivered 1500ms later to the participant's hand, to a task partner's hand, or to neither person. For the condition in which participants anticipated the tactile stimulation to their own hand, a negative potential (contingent negative variation, CNV) was observed in the ERP at central sites in the 1000ms prior to the tactile stimulus. Significant mu rhythm desynchronization was also present in the same time window. The magnitudes of the ERPs and of the mu desynchronization were greater in the contralateral than in the ipsilateral hemisphere prior to right hand stimulation. Similar ERP and EEG changes were not present when the visual cue indicated that stimulation would be delivered to the task partner or to neither person. The absence of social influences during anticipation of tactile stimulation, and the relationship between the two brain signatures of anticipatory attention (CNV and mu rhythm) are discussed. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Anticipated outcomes from introduction of 5-HTTLPR genotyping for depressed patients

    Østergaard, Svetlana; Møldrup, C

    2010-01-01

    rates with genotyping at first sight do not appear to be superior to existing practice, i.e. without genotyping. It is anticipated that a combination of 5-HTTLPR testing with other genomic variables, which have yet to be determined, and compliance measurements can improve clinical outcomes in the future...

  11. ATWS: a reappraisal. Part III. Frequency of anticipated transients. Interim report

    Leverenz, F.L. Jr.; Koren, J.M.; Erdmann, R.C.; Lellouche, G.S.

    1978-07-01

    The document is Part III of the Institute study of the ATWS question. The frequencies of the various events which have led to a reactor scram are documented from the nuclear power plant records. Some of these events, in the absence of scram, could lead to undesirable system response and are the ''transients of significance'' which comprise the anticipated transients of the ATWS question

  12. Old Anticipations, New Anxieties? A Contemporary Perspective on Primary to Secondary Transfer

    Mellor, David; Delamont, Sara

    2011-01-01

    The transfer from primary to secondary school in England and Wales is a status passage, from child to teenager. Research on the anxieties and anticipations surrounding that transfer over a 30-year period shows continuities and discontinuities. As well as the contrast of sociological approaches, the perceptions of children in 1977-1978 and…

  13. Constraints on Excuse Making: The Deterring Effects of Shyness and Anticipated Retest.

    Shepperd, James A.; And Others

    1995-01-01

    Examined whether the apparent absence of an egocentric bias among shy individuals is reflected in their excuse making following poor performance and whether anticipating a challenge to one's excuses would dissuade even nonshy individuals from making excuses. Shy individuals refrained form making consistency-lowering excuses regardless of…

  14. Effects of anticipated emotional category and temporal predictability on the startle reflex.

    Parisi, Elizabeth A; Hajcak, Greg; Aneziris, Eleni; Nelson, Brady D

    2017-09-01

    Anticipated emotional category and temporal predictability are key characteristics that have both been shown to impact psychophysiological indices of defensive motivation (e.g., the startle reflex). To date, research has primarily examined these features in isolation, and it is unclear whether they have additive or interactive effects on defensive motivation. In the present study, the startle reflex was measured in anticipation of low arousal neutral, moderate arousal pleasant, and high arousal unpleasant pictures that were presented with either predictable or unpredictable timing. Linear mixed-effects modeling was conducted to examine startle magnitude across time, and the intercept at the beginning and end of the task. Across the entire task, the anticipation of temporally unpredictable (relative to predictable) pictures and emotional (relative to neutral) pictures potentiated startle magnitude, but there was no interaction between the two features. However, examination of the intercept at the beginning of the task indicated a Predictability by Emotional Category interaction, such that temporal unpredictability enhanced startle potentiation in anticipation of unpleasant pictures only. Examination of the intercept at the end of the task indicated that the effects of predictability and emotional category on startle magnitude were largely diminished. The present study replicates previous reports demonstrating that emotional category and temporal predictability impact the startle reflex, and provides novel evidence suggesting an interactive effect on defensive motivation at the beginning of the task. This study also highlights the importance of examining the time course of the startle reflex. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Adaptive neural reward processing during anticipation and receipt of monetary rewards in mindfulness meditators.

    Kirk, Ulrich; Brown, Kirk Warren; Downar, Jonathan

    2015-05-01

    Reward seeking is ubiquitous and adaptive in humans. But excessive reward seeking behavior, such as chasing monetary rewards, may lead to diminished subjective well-being. This study examined whether individuals trained in mindfulness meditation show neural evidence of lower susceptibility to monetary rewards. Seventy-eight participants (34 meditators, 44 matched controls) completed the monetary incentive delay task while undergoing functional magnetic resonance imaging. The groups performed equally on the task, but meditators showed lower neural activations in the caudate nucleus during reward anticipation, and elevated bilateral posterior insula activation during reward anticipation. Meditators also evidenced reduced activations in the ventromedial prefrontal cortex during reward receipt compared with controls. Connectivity parameters between the right caudate and bilateral anterior insula were attenuated in meditators during incentive anticipation. In summary, brain regions involved in reward processing-both during reward anticipation and receipt of reward-responded differently in mindfulness meditators than in nonmeditators, indicating that the former are less susceptible to monetary incentives. © The Author (2014). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  16. Socio-cultural determinants of anticipated acceptance of an oral cholera vaccine in Western Kenya.

    Sundaram, N; Schaetti, C; Chaignat, C-L; Hutubessy, R; Nyambedha, E O; Mbonga, L A; Weiss, M G

    2013-03-01

    Determinants of anticipated acceptance of an oral cholera vaccine (OCV) were studied in urban and rural communities of Western Kenya. An explanatory model interview administered to 379 community residents assessed anticipated vaccine acceptance at various prices from no cost to full-cost recovery, socio-cultural features of cholera and social characteristics. Nearly all (99%) residents indicated willingness to accept a no-cost OCV, 95% at a price of US$ 0·8, 73% at US$ 4·2 and 59% at US$ 8·4. Logistic regression models analysed socio-cultural determinants of anticipated OCV acceptance. Prominence of non-specific symptoms for cholera was negatively associated with acceptance. A cholera-specific symptom (thirst), self-help referring to prayer, income and education were positively associated. In the high-cost model, education was no longer significant and reliance on herbal treatment was a significant determinant of vaccine non-acceptance. Findings suggest high motivation for OCVs, if affordable. Socio-cultural determinants are better predictors of anticipated acceptance than socio-demographic factors alone.

  17. Professional writers and empathy: Exploring the barriers to anticipating reader problems

    de Jong, Menno D.T.; Lentz, Leo

    2007-01-01

    Research has shown that professional writers cannot accurately predict the problems readers will experience when using functional documents. In this paper, we give an overview of reasons why it can be so hardfor writers to anticipate reader problems. We elaborate on the concept of empathy, and

  18. Age associations with neural processing of reward anticipation in adolescents with bipolar disorders

    Snežana Urošević

    2016-01-01

    Full Text Available Reward/behavioral approach system hypersensitivity is implicated in bipolar disorders (BD and in normative development during adolescence. Pediatric onset of BD is associated with a more severe illness course. However, little is known about neural processing of rewards in adolescents with BD or developmental (i.e., age associations with activation of these neural systems. The present study aims to address this knowledge gap. The present sample included 21 adolescents with BD and 26 healthy adolescents, ages 13 to 19. Participants completed a functional magnetic resonance imaging (fMRI protocol using the Monetary Incentive Delay (MID task. Behavioral performance was similar between groups. Group differences in BOLD activation during target anticipation and feedback anticipation periods of the task were examined using whole-brain analyses, as were group differences in age effects. During both target anticipation and feedback anticipation, adolescents with BD, compared to adolescents without psychopathology, exhibited decreased engagement of frontal regions involved in cognitive control (i.e., dorsolateral prefrontal cortex. Healthy adolescents exhibited age-related decreases, while adolescents with BD exhibited age-related increases, in activity of other cognitive control frontal areas (i.e., right inferior frontal gyrus, suggesting altered development in the BD group. Longitudinal research is needed to examine potentially abnormal development of cognitive control during reward pursuit in adolescent BD and whether early therapeutic interventions can prevent these potential deviations from normative development.

  19. The impact of anticipated stigma on psychological and physical health problems in the unemployed group

    Aisling T. O'Donnell

    2015-08-01

    Full Text Available Previous research has demonstrated that the unemployed suffer increased psychological and physical health problems compared to their employed counterparts. Further, unemployment leads to an unwanted new social identity that is stigmatizing, and stigma is known to be a stressor causing psychological and physical health problems. However, it is not yet known whether being stigmatized as an unemployed group member is associated with psychological and physical health in this group. The current study tested the impact of anticipated stigma on psychological distress and physical health problems, operationalized as somatic symptoms, in a volunteer sample of unemployed people. Results revealed that anticipated stigma had a direct effect on both psychological distress and somatic symptoms, such that greater anticipated stigma significantly predicted higher levels of both. Moreover, the direct effect on somatic symptoms became non-significant when psychological distress was taken into account. Thus, to the extent that unemployed participants anticipated experiencing greater stigma, they also reported increased psychological distress, and this psychological distress predicted increased somatic symptoms. Our findings complement and extend the existing literature on the relationships between stigmatized identities, psychological distress and physical health problems, particularly in relation to the unemployed group. This group is important to consider both theoretically, given the unwanted and transient nature of the identity compared to other stigmatized identities, but also practically, as the findings indicate a need to orient to the perceived valence of the unemployed identity and its effects on psychological and physical health.

  20. Anticipating climate change: knowledge use in participatory flood management in the river Meuse.

    Wesselink, A.; Reuber, J.; Krol, Martinus S.

    2005-01-01

    Given the latest knowledge on climate change, the Dutch government wants to anticipate the increased risk of flooding. For the river Meuse in The Netherlands, the design discharge is estimated to increase from 3800m3/s to 4600m3/s. With the existing policy of “Room for the River”, this increase is

  1. A genetic polymorphism of the endogenous opioid dynorphin modulates monetary reward anticipation in the corticostriatal loop.

    Mikhail Votinov

    Full Text Available The dynorphin/κ-opioid receptor (KOP-R system has been shown to play a role in different types of behavior regulation, including reward-related behavior and drug craving. It has been shown that alleles with 3 or 4 repeats (HH genotype of the variable nucleotide tandem repeat (68-bp VNTR functional polymorphism of the prodynorphin (PDYN gene are associated with higher levels of dynorphin peptides than alleles with 1 or 2 repeats (LL genotype. We used fMRI on N = 71 prescreened healthy participants to investigate the effect of this polymorphism on cerebral activation in the limbic-corticostriatal loop during reward anticipation. Individuals with the HH genotype showed higher activation than those with the LL genotype in the medial orbitofrontal cortex (mOFC when anticipating a possible monetary reward. In addition, the HH genotype showed stronger functional coupling (as assessed by effective connectivity analyses of mOFC with VMPFC, subgenual anterior cingulate cortex, and ventral striatum during reward anticipation. This hints at a larger sensitivity for upcoming rewards in individuals with the HH genotype, resulting in a higher motivation to attain these rewards. These findings provide first evidence in humans that the PDYN polymorphism modulates neural processes associated with the anticipation of rewards, which ultimately may help to explain differences between genotypes with respect to addiction and drug abuse.

  2. A genetic polymorphism of the endogenous opioid dynorphin modulates monetary reward anticipation in the corticostriatal loop.

    Votinov, Mikhail; Pripfl, Juergen; Windischberger, Christian; Kalcher, Klaudius; Zimprich, Alexander; Zimprich, Fritz; Moser, Ewald; Lamm, Claus; Sailer, Uta

    2014-01-01

    The dynorphin/κ-opioid receptor (KOP-R) system has been shown to play a role in different types of behavior regulation, including reward-related behavior and drug craving. It has been shown that alleles with 3 or 4 repeats (HH genotype) of the variable nucleotide tandem repeat (68-bp VNTR) functional polymorphism of the prodynorphin (PDYN) gene are associated with higher levels of dynorphin peptides than alleles with 1 or 2 repeats (LL genotype). We used fMRI on N = 71 prescreened healthy participants to investigate the effect of this polymorphism on cerebral activation in the limbic-corticostriatal loop during reward anticipation. Individuals with the HH genotype showed higher activation than those with the LL genotype in the medial orbitofrontal cortex (mOFC) when anticipating a possible monetary reward. In addition, the HH genotype showed stronger functional coupling (as assessed by effective connectivity analyses) of mOFC with VMPFC, subgenual anterior cingulate cortex, and ventral striatum during reward anticipation. This hints at a larger sensitivity for upcoming rewards in individuals with the HH genotype, resulting in a higher motivation to attain these rewards. These findings provide first evidence in humans that the PDYN polymorphism modulates neural processes associated with the anticipation of rewards, which ultimately may help to explain differences between genotypes with respect to addiction and drug abuse.

  3. How to come to military platforms that are capable to perform the anticipated tasks and missions

    Smit, C.S.; Rijn, T.P.J. van

    2010-01-01

    A programme has been performed in the Netherlands to realise a framework to support the armed forces during the procurement of (land based) platforms. The aim is to procure platforms that are capable to perform the anticipated tasks and missions. The support comprises two aspects: formulation of

  4. Resilience Training for Hospital Workers in Anticipation of an Influenza Pandemic

    Aiello, Andria; Khayeri, Michelle Young-Eun; Raja, Shreyshree; Peladeau, Nathalie; Romano, Donna; Leszcz, Molyn; Maunder, Robert G.; Rose, Marci; Adam, Mary Anne; Pain, Clare; Moore, Andrea; Savage, Diane; Schulman, Rabbi Bernard

    2011-01-01

    Background: Well before the H1N1 influenza, health care organizations worldwide prepared for a pandemic of unpredictable impact. Planners anticipated the possibility of a pandemic involving high mortality, high health care demands, rates of absenteeism rising up to 20-30% among health care workers, rationing of health care, and extraordinary…

  5. Employees' intentions to retire early : a case of planned behavior and anticipated work conditions

    van Dam, Karen; van der Vorst, Janine D.M.; van der Heijden, Beatrice

    2009-01-01

    This study investigated the early retirement intentions of 346 older Dutch employees by extending the theory of planned behavior with anticipated work conditions. The results showed that employees who felt a pressure from their spouse to retire early had a strong intention to leave the work force

  6. Attention! An affective approach to anticipated action : Cognitive, affective, and motivational processes underlying proactive behavior

    Wolsink, I.

    2017-01-01

    Proactivity is popular: on vacancy websites, ‘proactive’ generates more hits than any other competency. Proactive individuals do not wait for instructions. They actively try to anticipate future problems and opportunities and initiate improvement in themselves and their environment. Despite

  7. The self-regulatory function of anticipated pride and guilt in sustainable and health consumption

    Onwezen, M.C.; Bartels, J.; Antonides, G.

    2014-01-01

    Although individuals generally value health and sustainability, they do not always behave in a manner that is consistent with their standards. The current study examines whether attitudes and social norms (i.e., descriptive and injunctive norms) can evoke anticipated pride and guilt, which, in turn,

  8. Under stochastic dominance Choquet-expected utility and anticipated utility are identical

    P.P. Wakker (Peter)

    1990-01-01

    textabstractThe aim of this paper is to convince the reader that Choquet-expected utility, as initiated by Schmeidler (1982, 1989) for decision making under uncertainty, when formulated for decision making under risk naturally leads to anticipated utility, as initiated by Quiggin/Yaari. Thus the two

  9. Under stochastic dominance choquet-expected utility and anticipated utility are identical

    Wakker, P.P.

    1990-01-01

    The aim of this paper is to convince the reader that Choquet-expected utility, as initiated by Schmeidler (1982) for decision making under uncertainty, when formulated for decision making under risk naturally leads to Yaari (1987)'s anticipated utility. Thus the two generalizations of expected

  10. The influence of anticipated regret on business start-up behaviour: A research note

    Hatak, Isabella; Snellman, Kirsi

    This research note aims to develop the emotional underpinning of early-stage entrepreneurship by examining the influence of anticipated regret, a negative emotion, on the transformation of latent entrepreneurs into nascent entrepreneurs. Drawing on regret regulation theory and two waves of survey

  11. 76 FR 37661 - Notification of Anticipated Delay in Administrative Appeal Decisions

    2011-06-28

    ... material ``Self-reactive solid, Type F, UN3230.'' Dangerous Goods Transport Appeal focuses on the...] Notification of Anticipated Delay in Administrative Appeal Decisions AGENCY: Pipeline and Hazardous Materials... currently reviewing numerous administrative appeals (i.e., petitions for reconsideration) on recently issued...

  12. Bayesian Modeling for Genetic Anticipation in Presence of Mutational Heterogeneity: A Case Study in Lynch Syndrome

    Boonstra, Philip S; Mukherjee, Bhramar; Taylor, Jeremy M G

    2011-01-01

    to cause hereditary nonpolyposis colorectal cancer, also called Lynch syndrome (LS). We find evidence for a decrease in AOO between generations in this article. Our model predicts family-level anticipation effects that are potentially useful in genetic counseling clinics for high-risk families....

  13. Women’s Work and Divorce : A Matter of Anticipation? A Research Note

    Poortman, Anne-Rigt

    2005-01-01

    The most common hypothesis on the positive association between wives’ work and divorce is that the wife’s work increases the risk of divorce. Critics argue that the causal direction is the other way around and that women adjust their working hours in anticipation of divorce. These competing

  14. Women's work and divorce: a matter of anticipation? A research note

    Poortman, A.R.

    2005-01-01

    The most common hypothesis on the positive association between wives' work and divorce is that the wife's work increases the risk of divorce. Critics argue that the causal direction is the other way around and that women adjust their working hours in anticipation of divorce. These competing

  15. The effects of anticipated regret on risk preferences of social and problem gamblers

    Karin Tochkov

    2009-04-01

    Full Text Available Anticipated regret is an important determinant in risky decision making, however only a few studies have explored its role in problem gambling. This study tested for differences in the anticipation of regret among social and problem gamblers and examined how these differences affect risk preferences in a gambling task. The extent of problem gambling was assessed using the South Oaks Gambling Screen and participants were randomly assigned to one of two conditions. In the risky feedback condition, the feeling of regret was avoided by choosing the risky gamble, whereas in the safe feedback condition the safe gamble was the regret-minimizing option. Problem gambling was associated with the choice of the risky gamble in both conditions indicating less sensitivity to anticipated regret. It was also associated with risk seeking across feedback conditions when the stakes of winning and loosing were higher. These findings suggest that less regret or the poor anticipation of regret might contribute to excessive gambling and thus need to be addressed in cognitive treatments of problem gambling.

  16. Anticipated Work-Family Conflict: Effects of Role Salience and Self-Efficacy

    Cinamon, Rachel Gali

    2010-01-01

    The current study investigated how male and female university students' self-efficacy and their role salience contributed to the variance in their anticipated work-family conflict (WFC). Participants comprised 387 unmarried students (mean age 24 years). Cluster analysis yielded four profiles of participants who differed in their attributions of…

  17. Will Marriage Matter? Effects of Marriage Anticipated by Same-Sex Couples

    Shulman, Julie L.; Gotta, Gabrielle; Green, Robert-Jay

    2012-01-01

    The current study used an online survey to explore the anticipated impact of legalized marriage on partners in same-sex couples living in California. These data were gathered prior to the California Supreme Court decision in May 2008 legalizing same-sex marriage, which held sway for 5 months before California Proposition 8 eliminating same-sex…

  18. The "ick" factor, anticipated regret, and willingness to become an organ donor.

    O'Carroll, Ronan E; Foster, Catherine; McGeechan, Grant; Sandford, Kayleigh; Ferguson, Eamonn

    2011-03-01

    This research tested the role of traditional rational-cognitive factors and emotional barriers to posthumous organ donation. An example of an emotional barrier is the "ick" factor, a basic disgust reaction to the idea of organ donation. We also tested the potential role of manipulating anticipated regret to increase intention to donate in people who are not yet registered organ donors. In three experiments involving 621 members of the United Kingdom general public, participants were invited to complete questionnaire measures tapping potential emotional affective attitude barriers such as the "ick" factor, the desire to retain bodily integrity after death, and medical mistrust. Registered posthumous organ donors were compared with nondonors. In Experiments 2 and 3, nondonors were then allocated to a simple anticipated regret manipulation versus a control condition, and the impact on intention to donate was tested. Self-reported emotional barriers and intention to donate in the future. Traditional rational-cognitive factors such as knowledge, attitude, and subjective norm failed to distinguish donors from nondonors. However, in all three experiments, nondonors scored significantly higher than donors on the emotional "ick" factor and bodily integrity scales. A simple anticipated regret manipulation led to a significant increase in intention to register as an organ donor in future. Negative affective attitudes are thus crucial barriers to people registering as organ donors. A simple anticipated regret manipulation has the potential to significantly increase organ donation rates. (c) 2011 APA, all rights reserved

  19. "I Want, Therefore I Am" - Anticipated Upward Mobility Reduces Ingroup Concern.

    Chipeaux, Marion; Kulich, Clara; Iacoviello, Vincenzo; Lorenzi-Cioldi, Fabio

    2017-01-01

    Empirical findings suggest that members of socially disadvantaged groups who join a better-valued group through individual achievement tend to express low concern for their disadvantaged ingroup (e.g., denial of collective discrimination, low intent to initiate collective action). In the present research, we investigated whether this tendency occurs solely for individuals who have already engaged in social mobility, or also for individuals who psychologically prepare themselves, that is 'anticipate', social mobility. Moreover, we examined the role of group identification in this process. In two studies, we looked at the case of 'frontier workers', that is people who cross a national border every day to work in another country where the salaries are higher thereby achieving a better socio-economic status than in their home-country. Study 1 ( N = 176) examined attitudes of French nationals (both the socially mobile and the non-mobile) and of Swiss nationals toward the non-mobile group. As expected, results showed that the mobile French had more negative attitudes than their non-mobile counterparts, but less negative attitudes than the Swiss. In Study 2 ( N = 216), we examined ingroup concern at different stages of the social mobility process by comparing the attitudes of French people who worked in Switzerland (mobile individuals), with those who envisioned (anticipators), or not (non-anticipators), to work in Switzerland. The findings revealed that anticipators' motivation to get personally involved in collective action for their French ingroup was lower than the non-anticipators', but higher than the mobile individuals'. Moreover, we found that the decrease in ingroup concern across the different stages of social mobility was accounted for by a lower identification with the inherited ingroup. These findings corroborate the deleterious impact of social mobility on attitudes toward a low-status ingroup, and show that the decrease in ingroup concern already occurs

  20. Asie du sud | Page 107 | CRDI - Centre de recherches pour le ...

    In this spirit, Viet Nam's Minister of Science, Technology and Environment approached the International Development Research Centre ( IDRC ) and the ... of social difference is needed to find answers to the questions of who participates and how, and who benefits and how from development interventions, projects, ...