WorldWideScience

Sample records for central-to-axial chirality transfer

  1. Central-to-axial chirality transfer revealed by liquid crystals: a combined experimental and computational approach for the determination of absolute configuration of carboxylic acids with an α chirality centre.

    Science.gov (United States)

    Ferrarini, Alberta; Ferroni, Fiammetta; Pieraccini, Silvia; Rosini, Carlo; Superchi, Stefano; Spada, Gian Piero

    2011-10-01

    The conversion into 6,7-dihydro-5H-dibenz[c,e]azepine (DAZ) N-protected amides is a viable route for the determination of the absolute configuration of chiral 2-substituted carboxylic acids. The biphenyl moiety of DAZ, besides being a probe of chirality for the electronic circular dichroism (ECD) spectroscopy, makes these systems suitable for configuration assignment by exploiting the chirality amplification which occurs in nematic liquid crystals. To assess the reliability of the liquid crystal method in detecting the absolute stereochemistry of chiral amides bound to a biphenyl group, we measured the helical twisting power of a series of DAZ-N-protected amides and compared these data with the results obtained from ECD measurements. We will show that the liquid crystal method, corroborated by HTP predictions, is trustworthy with our biphenyl derivatives, even when ECD spectra are ambiguous for the presence of aryl moieties displaying strong UV absorptions in the same range of the biphenyl chromophore.

  2. Gelation induced supramolecular chirality: chirality transfer, amplification and application.

    Science.gov (United States)

    Duan, Pengfei; Cao, Hai; Zhang, Li; Liu, Minghua

    2014-08-14

    Supramolecular chirality defines chirality at the supramolecular level, and is generated from the spatial arrangement of component molecules assembling through non-covalent interactions such as hydrogen bonding, van der Waals interactions, π-π stacking, hydrophobic interactions and so on. During the formation of low molecular weight gels (LMWGs), one kind of fascinating soft material, one frequently encounters the phenomenon of chirality as well as chiral nanostructures, either from chiral gelators or even achiral gelators. A view of gelation-induced supramolecular chirality will be very helpful to understand the self-assembly process of the gelator molecules as well as the chiral structures, the regulation of the chirality in the gels and the development of the "smart" chiral materials such as chiroptical devices, catalysts and chiral sensors. It necessitates fundamental understanding of chirality transfer and amplification in these supramolecular systems. In this review, recent progress in gelation-induced supramolecular chirality is discussed.

  3. Dynamic chirality, chirality transfer and aggregation behaviour of dithienylethene switches

    NARCIS (Netherlands)

    de Jong, Jaap J. D.; van Rijn, Patrick; Tiemersma-Wegeman, Theodora D.; Lucas, Linda N.; Browne, Wesley R.; Kellogg, Richard M.; Uchida, Kingo; Van Esch, Jan H.; Feringa, Ben L.

    2008-01-01

    The synthesis and characterisation of a series of chiral and achiral low molecular weight organogelators (LMWGs) based on bis-amide substituted dithienylethene photochromic switches is reported. The LMWGs gelate a range of solvents depending on the specific functionalisation of the hydrogen bonding

  4. Enantiomer-Specific State Transfer of Chiral Molecules

    CERN Document Server

    Eibenberger, Sandra; Patterson, David

    2016-01-01

    State-selective enantiomeric excess is realized using microwave-driven coherent population transfer. The method selectively promotes either R- or S- molecules to a higher rotational state by phase-controlled microwave pulses that drive electric-dipole allowed rotational transitions. We demonstrate the method using a racemic mixture of 1,2-propanediol. This method of chiral enrichment can be applied to nearly any chiral molecule that can be vaporized and cooled to the point where rotationally resolved spectroscopy is possible, including molecules that rapidly racemize. The rapid chiral switching demonstrated here allows for new applications in high-precision spectroscopic searches for parity violation in chiral molecules.

  5. Role of Achiral Nucleobases in Multicomponent Chiral Self-Assembly: Purine-Triggered Helix and Chirality Transfer.

    Science.gov (United States)

    Deng, Ming; Zhang, Li; Jiang, Yuqian; Liu, Minghua

    2016-11-21

    Chiral self-assembly is a basic process in biological systems, where many chiral biomolecules such as amino acids and sugars play important roles. Achiral nucleobases usually covalently bond to saccharides and play a significant role in the formation of the double helix structure. However, it remains unclear how the achiral nucleobases can function in chiral self-assembly without the sugar modification. Herein, we have clarified that purine nucleobases could trigger N-(9-fluorenylmethox-ycarbonyl) (Fmoc)-protected glutamic acid to self-assemble into helical nanostructures. Moreover, the helical nanostructure could serve as a matrix and transfer the chirality to an achiral fluorescence probe, thioflavin T (ThT). Upon chirality transfer, the ThT showed not only supramolecular chirality but also circular polarized fluorescence (CPL). Without the nucleobase, the self-assembly processes cannot happen, thus providing an example where achiral molecules played an essential role in the expression and transfer of the chirality.

  6. Mass transfer mechanism in chiral reversed phase liquid chromatography.

    Science.gov (United States)

    Gritti, Fabrice; Guiochon, Georges

    2014-03-01

    The mechanism of mass transfer in chiral chromatography was investigated using an experimental protocol already applied in RPLC and HILIC chromatography. The different contributions to the reduced height equivalent to a theoretical plate (HETP) include the longitudinal diffusion HETP term, the solid-liquid mass transfer resistance HETP term, the short-range eddy dispersion HETP term, and the long-range eddy dispersion HETP term. Their accurate measurement permits the determination of the adsorption rate constant kads of trans-stilbene enantiomers on a column packed with Lux 5 μm Cellulose-1 particles. The experimental results demonstrate that the number of adsorption-desorption steps per unit time of chiral compounds on polysaccharide-based chiral stationary phases is four orders of magnitude smaller than that of achiral compounds.

  7. A chiroptical switch based on supramolecular chirality transfer through alkyl chain entanglement and dynamic covalent bonding.

    Science.gov (United States)

    Lv, Kai; Qin, Long; Wang, Xiufeng; Zhang, Li; Liu, Minghua

    2013-12-14

    Chirality transfer is an interesting phenomenon in Nature, which represents an important step to understand the evolution of chiral bias and the amplification of the chirality. In this paper, we report the chirality transfer via the entanglement of the alkyl chains between chiral gelator molecules and achiral amphiphilic Schiff base. We have found that although an achiral Schiff base amphiphile could not form organogels in any kind of organic solvents, it formed co-organogels when mixed with a chiral gelator molecule. Interestingly, the chirality of the gelator molecules was transferred to the Schiff base chromophore in the mixed co-gels and there was a maximum mixing ratio for the chirality transfer. Furthermore, the supramolecular chirality was also produced based on a dynamic covalent chemistry of an imine formed by the reaction between an aldehyde and an amine. Such a covalent bond of imine was formed reversibly depending on the pH variation. When the covalent bond was formed the chirality transfer occurred, when it was destroyed, the transfer stopped. Thus, a supramolecular chiroptical switch is obtained based on supramolecular chirality transfer and dynamic covalent chemistry.

  8. Asymmetric transfer hydrogenation of imines catalyzed by a polymer-immobilized chiral catalyst.

    Science.gov (United States)

    Haraguchi, Naoki; Tsuru, Keiichi; Arakawa, Yukihiro; Itsuno, Shinichi

    2009-01-07

    The asymmetric transfer hydrogenation of imines was performed with the use of a polymer-immobilized chiral catalyst. The chiral catalyst, prepared from crosslinked polystyrene-immobilized chiral 1,2-diamine monosulfonamide, was effective in the asymmetric transfer hydrogenation of N-benzyl imines in CH(2)Cl(2) to give a chiral amine in high yield and good enantioselectivity. Furthermore, an amphiphilic polymeric catalyst prepared from crosslinked polystyrene containing sulfonated groups successfully catalyzed the asymmetric transfer hydrogenation of cyclic imines in water. Enantioenriched secondary amines with up to 94% ee were obtained by using a polymeric catalyst.

  9. Supramolecular helices: chirality transfer from conjugated molecules to structures.

    Science.gov (United States)

    Yang, Yang; Zhang, Yajie; Wei, Zhixiang

    2013-11-13

    Different scales of chirality endow a material with many excellent properties and potential applications. In this review, using π-conjugated molecules as functional building blocks, recent progress on supramolecular helices inspired by biological helicity is summarized. First, induced chirality on conjugated polymers and small molecules is introduced. Molecular chirality can be amplified to nanostructures, superstructures, and even macroscopic structures by a self-assembly process. Then, the principles for tuning the helicity of supramolecular chirality, as well as formation of helical heterojunctions, are summarized. Finally, the potential applications of chiral structures in chiral sensing and organic electronic devices are critically reviewed. Due to recent progress in chiral structures, an interdisciplinary area called "chiral electronics" is expected to gain wide popularity in the near future.

  10. Chirality Transfer in Gold(I)-Catalysed Direct Allylic Etherifications of Unactivated Alcohols: Experimental and Computational Study.

    Science.gov (United States)

    Barker, Graeme; Johnson, David G; Young, Paul C; Macgregor, Stuart A; Lee, Ai-Lan

    2015-09-21

    Gold(I)-catalysed direct allylic etherifications have been successfully carried out with chirality transfer to yield enantioenriched, γ-substituted secondary allylic ethers. Our investigations include a full substrate-scope screen to ascertain substituent effects on the regioselectivity, stereoselectivity and efficiency of chirality transfer, as well as control experiments to elucidate the mechanistic subtleties of the chirality-transfer process. Crucially, addition of molecular sieves was found to be necessary to ensure efficient and general chirality transfer. Computational studies suggest that the efficiency of chirality transfer is linked to the aggregation of the alcohol nucleophile around the reactive π-bound Au-allylic ether complex. With a single alcohol nucleophile, a high degree of chirality transfer is predicted. However, if three alcohols are present, alternative proton transfer chain mechanisms that erode the efficiency of chirality transfer become competitive.

  11. The asymmetric alkylation of dimethylhydrazones; intermolecular chirality transfer using sparteine as chiral ligand.

    Science.gov (United States)

    McSweeney, Christina M; Foley, Vera M; McGlacken, Gerard P

    2014-12-01

    The asymmetric alkylation of ketones represents a fundamental transformation in organic chemistry. Chiral auxiliaries have been used almost exclusively for this transformation. Herein we describe a strategy for the generation of enantiomerically enriched α-alkylated ketones up to an er of 83 : 17, using a chiral ligand protocol.

  12. Direct Observation of Molecular Preorganization for Chirality Transfer on a Catalyst Surface

    DEFF Research Database (Denmark)

    Demers-Carpentier, Vincent; Goubert,, Guillaume; Masini, Federico

    2011-01-01

    The chemisorption of specific optically active compounds on metal surfaces can create catalytically active chirality transfer sites. However, the mechanism through which these sites bias the stereoselectivity of reactions (typically hydrogenations) is generally assumed to be so complex that conti......The chemisorption of specific optically active compounds on metal surfaces can create catalytically active chirality transfer sites. However, the mechanism through which these sites bias the stereoselectivity of reactions (typically hydrogenations) is generally assumed to be so complex...... functional theory calculations reveals the stereodirecting forces governing preorganization into precise chiral modifier-substrate bimolecular surface complexes. The study shows that the chiral modifier induces prochiral switching on the surface and that different prochiral ratios prevail at different...

  13. Supramolecular Chirality: Solvent Chirality Transfer in Molecular Chemistry and Polymer Chemistry

    Directory of Open Access Journals (Sweden)

    Michiya Fujiki

    2014-08-01

    Full Text Available Controlled mirror symmetry breaking arising from chemical and physical origin is currently one of the hottest issues in the field of supramolecular chirality. The dynamic twisting abilities of solvent molecules are often ignored and unknown, although the targeted molecules and polymers in a fluid solution are surrounded by solvent molecules. We should pay more attention to the facts that mostly all of the chemical and physical properties of these molecules and polymers in the ground and photoexcited states are significantly influenced by the surrounding solvent molecules with much conformational freedom through non-covalent supramolecular interactions between these substances and solvent molecules. This review highlights a series of studies that include: (i historical background, covering chiral NaClO3 crystallization in the presence of d-sugars in the late 19th century; (ii early solvent chirality effects for optically inactive chromophores/fluorophores in the 1960s–1980s; and (iii the recent development of mirror symmetry breaking from the corresponding achiral or optically inactive molecules and polymers with the help of molecular chirality as the solvent use quantity.

  14. Synthesis of racemic and chiral BEDT-TTF derivatives possessing hydroxy groups and their achiral and chiral charge transfer complexes

    Directory of Open Access Journals (Sweden)

    Sara J. Krivickas

    2015-09-01

    Full Text Available Chiral molecular crystals built up by chiral molecules without inversion centers have attracted much interest owing to their versatile functionalities related to optical, magnetic, and electrical properties. However, there is a difficulty in chiral crystal growth due to the lack of symmetry. Therefore, we made the molecular design to introduce intermolecular hydrogen bonds in chiral crystals. Racemic and enantiopure bis(ethylenedithiotetrathiafulvalene (BEDT-TTF derivatives possessing hydroxymethyl groups as the source of hydrogen bonds were designed. The novel racemic trans-vic-(hydroxymethyl(methyl-BEDT-TTF 1, and racemic and enantiopure trans-vic-bis(hydroxymethyl-BEDT-TTF 2 were synthesized. Moreover, the preparations, crystal structure analyses, and electrical resistivity measurements of the novel achiral charge transfer salt θ21-[(S,S-2]3[(R,R-2]3(ClO42 and the chiral salt α’-[(R,R-2]ClO4(H2O were carried out. In the former θ21-[(S,S-2]3[(R,R-2]3(ClO42, there are two sets of three crystallographically independent donor molecules [(S,S-2]2[(R,R-2] in a unit cell, where the two sets are related by an inversion center. The latter α’-[(R,R-2]ClO4(H2O is the chiral salt with included solvent H2O, which is not isostructural with the reported chiral salt α’-[(S,S-2]ClO4 without H2O, but has a similar donor arrangement. According to the molecular design by introduction of hydroxy groups and a ClO4− anion, many intermediate-strength intermolecular hydrogen bonds (2.6–3.0 Å were observed in these crystals between electron donor molecules, anions, and included H2O solvent, which improve the crystallinity and facilitate the extraction of physical properties. Both salts are semiconductors with relatively low resistivities at room temperature and activation energies of 1.2 ohm cm with Ea = 86 meV for θ21-[(S,S-2]3[(R,R-2]3(ClO42 and 0.6 ohm cm with Ea = 140 meV for α'-[(R,R-2]2ClO4(H2O, respectively. The variety of donor arrangements

  15. Novel Chiral PNNP-Ru Complexes: Synthesis and Application in Asymmetric Transfer Hydrogenation of Ketones

    Institute of Scientific and Technical Information of China (English)

    CHENG Zhi-bo; YU Shen-luan; LI Yan-yun; DONG Zhen-rong; SUN Guo-song; HUANG Ke-lin; GAO Jing-xing

    2011-01-01

    The efficient catalytic systems generated in situ from RuCl2(PPh3)3 and chiral ligands N,N-bis[2-(di-otolylphosphino)-benzyl]cyclohexane-l,2-diamine(2) were employed for asymmetric transfer hydrogenation of aromatic ketones, giving the corresponding optically active alcohols with high activities(up to 99% conversion) and excellent enantioselectivities(up to 96% e.e.) under mild conditions. The chiral ruthenium(Ⅱ) complex (R,R)-3 has been prepared and characterized by NMR and X-ray crystallography.

  16. Atropselective syntheses of (-) and (+) rugulotrosin A utilizing point-to-axial chirality transfer

    Science.gov (United States)

    Qin, Tian; Skraba-Joiner, Sarah L.; Khalil, Zeinab G.; Johnson, Richard P.; Capon, Robert J.; Porco, John A.

    2015-03-01

    Chiral, dimeric natural products containing complex structures and interesting biological properties have inspired chemists and biologists for decades. A seven-step total synthesis of the axially chiral, dimeric tetrahydroxanthone natural product rugulotrosin A is described. The synthesis employs a one-pot Suzuki coupling/dimerization to generate the requisite 2,2‧-biaryl linkage. Highly selective point-to-axial chirality transfer was achieved using palladium catalysis with achiral phosphine ligands. Single X-ray crystal diffraction data were obtained to confirm both the atropisomeric configuration and absolute stereochemistry of rugulotrosin A. Computational studies are described to rationalize the atropselectivity observed in the key dimerization step. Comparison of the crude fungal extract with synthetic rugulotrosin A and its atropisomer verified that nature generates a single atropisomer of the natural product.

  17. Inter-instrumental method transfer of chiral capillary electrophoretic methods using robustness test information.

    Science.gov (United States)

    De Cock, Bart; Borsuk, Agnieszka; Dejaegher, Bieke; Stiens, Johan; Mangelings, Debby; Vander Heyden, Yvan

    2014-08-01

    Capillary electrophoresis (CE) is an electrodriven separation technique that is often used for the separation of chiral molecules. Advantages of CE are its flexibility, low cost and efficiency. On the other hand, the precision and transfer of CE methods are well-known problems of the technique. Reasons for the more complicated method transfer are the more diverse instrumental differences, such as total capillary lengths and capillary cooling systems; and the higher response variability of CE methods compared to other techniques, such as liquid chromatography (HPLC). Therefore, a larger systematic change in peak resolutions, migration times and peak areas, with a loss of separation and efficiency may be seen when a CE method is transferred to another laboratory or another type of instrument. A swift and successful method transfer is required because development and routine use of analytical methods are usually not performed in the same laboratory and/or on the same type of equipment. The aim of our study was to develop transfer rules to facilitate CE method transfers between different laboratories and instruments. In our case study, three β-blockers were chirally separated and inter-instrumental transfers were performed. The first step of our study was to optimise the precision of the chiral CE method. Next, a robustness test was performed to identify the instrumental and experimental parameters that were most influencing the considered responses. The precision- and the robustness study results were used to adapt instrumental and/or method settings to improve the transfer between different instruments. Finally, the comparison of adapted and non-adapted transfers allowed deriving some rules to facilitate CE method transfers.

  18. Catalytic Enantioselective Aryl Transfer to Aldehydes Using Chiral 2,2’-Bispyrrolidine-Based Salan Ligands

    Directory of Open Access Journals (Sweden)

    Yixiang Cheng

    2011-04-01

    Full Text Available Chiral C2-symmetric diamines have emerged as versatile auxiliaries or ligands in numerous asymmetric transformations. Chiral 2,2’-bispyrrolidine-based salan ligands were prepared and applied to the asymmetric aryl transfer to aldehydes with arylboronic acids as the source of transferable aryl groups. The corresponding diarylmethanols were obtained in high yields with moderate to good enantioselectivitives of up to 83% ee.

  19. Asymmetric cyclopropanation of chalcones using chiral phase-transfer catalysts

    OpenAIRE

    2013-01-01

    The first phase-transfer catalyzed cyclopropanation reaction of chalcones using bromomalonates as the nucleophiles in a Michael Initiated Ring Closing reaction (MIRC) was developed. Key to success was the use of a free OH-containing cinchona alkaloid ammonium salt catalyst and carefully optimized liquid/liquid reaction conditions. The reaction performed well for electron neutral and electron deficient chalcones giving the products in yields up to 98% and with enantiomeric ratios up to 91:9.

  20. Synthesis of novel chiral N, P-containing multidentate ligands and their applications in asymmetric transfer hydrogenation

    Institute of Scientific and Technical Information of China (English)

    Shen Luan Yu; Yan Yun Li; Zhen Rong Dong; Juan Ni Zhang; Qi Li; Jing Xing Gao

    2011-01-01

    Novel chiral PN4-type multidentate aminophosphine ligands have been successfully synthesized by Schiff-base condensation of bis(o-formylphenyl)phenylphosphane and various chiral amino-sulfonamides. Their structures were fully characterized by IR, EI-MS and NMR. The catalytic systems, prepared in situ from the multidentate ligands and iridium(I) complexes, showed high activity in asymmetric transfer hydrogenation of propiophenone in 2-propanol solution, leading to corresponding optical alcohol with up to 75% ee.

  1. Synthesis of novel chiral tetraaza ligands and their application in enantioselective transfer hydrogenation of ketones

    Institute of Scientific and Technical Information of China (English)

    Shen Luan Yu; Yan Yun Li; Zhen Rong Dong; Jing Xing Gao

    2012-01-01

    Novel chiral tetraaza ligands (R)-N,N'-bis[2-(piperidin-l-yl)benzylidene]propane-1,2-diamine 6 and (S)-N-[2-(piperidin-1-yl)benzylidene]-3-{ [2-(piperidin-1-yl)benzylidene]amino}-alanine sodium salt 7 have been synthesized and fully characterized by NMR,IR,MS and CD spectra.The catalytic property of the ligands was investigated in Ir-catalyzed enantioselective transfer hydrogenation of ketones.The corresponding optical active alcohols were obtained with high yields and moderate ees under mild reaction conditions.

  2. Chiral Selectivity in Inter-reactant Recognition and Electron Transfer of the Oxidation of Horse Heart Cytochrome c by Trioxalatocobaltate(III)

    DEFF Research Database (Denmark)

    Nazmutdinov, Renat R.; Bronshtein, Michael D.; Zinkicheva, Tamara T.;

    2016-01-01

    We have studied electron transfer between cytochrome c and the chiral transition-metal complex pair Λ- and Δ-[Co(Ox)3]3− (Ox2− = oxalate) via strong ion-pair formation. Chirality was found in both ion-pair formation and electron transfer, with the Λ enantiomer the more strongly bound and faster r...... reacting. Investigations of the chirality using electron-transfer theory combined with quantum-chemical and statistical-mechanical calculations showed that chirality is solely in inter-reactant interaction and electronic overlap....

  3. Enantioselective synthesis of angularly substituted 1-azabicylic rings: coupled dynamic kinetic epimerization and chirality transfer.

    Science.gov (United States)

    Aron, Zachary D; Ito, Tatsuya; May, Tricia L; Overman, Larry E; Wang, Jocelyn

    2013-10-01

    A new strategy for enantioselective synthesis of azacyclic molecules in which dynamic kinetic equilibration of diastereomeric iminium ions precedes a stereochemistry-determining sigmatropic rearrangement is reported. The method is illustrated by the synthesis, in high enantiomeric purity (generally 95-99% ee), of a variety of 1-azabicyclic molecules containing angular allyl or 3-substituted 2-propenyl side chains adjacent to nitrogen and up to three stereogenic centers. In these products, the size of the carbocyclic ring is varied widely (5-12 membered); however, useful yields are obtained in forming 1-azabicyclic products containing only fused pyrrolidine and piperidine rings. Chirality transfer from substituents at carbons 1 and 2 of the 3-butenylamine fragment of the starting material is investigated, with methyl and phenyl substituents at the allylic position shown to provide exquisite stereocontrol (generally 98-99% chirality transfer). An attractive feature of the method is the ability to carry out the key transformation in the absence of solvent. Illustrated also is the high yielding conversion of four such products to a new family of bicyclic β-amino acids of high enantiomeric purity.

  4. Cold denaturation induces inversion of dipole and spin transfer in chiral peptide monolayers

    Science.gov (United States)

    Eckshtain-Levi, Meital; Capua, Eyal; Refaely-Abramson, Sivan; Sarkar, Soumyajit; Gavrilov, Yulian; Mathew, Shinto P.; Paltiel, Yossi; Levy, Yaakov; Kronik, Leeor; Naaman, Ron

    2016-02-01

    Chirality-induced spin selectivity is a recently-discovered effect, which results in spin selectivity for electrons transmitted through chiral peptide monolayers. Here, we use this spin selectivity to probe the organization of self-assembled α-helix peptide monolayers and examine the relation between structural and spin transfer phenomena. We show that the α-helix structure of oligopeptides based on alanine and aminoisobutyric acid is transformed to a more linear one upon cooling. This process is similar to the known cold denaturation in peptides, but here the self-assembled monolayer plays the role of the solvent. The structural change results in a flip in the direction of the electrical dipole moment of the adsorbed molecules. The dipole flip is accompanied by a concomitant change in the spin that is preferred in electron transfer through the molecules, observed via a new solid-state hybrid organic-inorganic device that is based on the Hall effect, but operates with no external magnetic field or magnetic material.

  5. Effective Chirality Transfer in [3+2] Reaction between Allenyl-Rhodium and Enal: Mechanistic Study Based on DFT Calculations.

    Science.gov (United States)

    Qi, Xiaotian; Liu, Song; Zhang, Tao; Long, Rong; Huang, Jun; Gong, Jianxian; Yang, Zhen; Lan, Yu

    2016-09-16

    Theoretical calculation was performed to study the chirality transfer in a newly reported intramolecular [3+2] cycloaddition of enal and alleno rhodium species, generated in situ from an enynol precursor. [3.3.0] bicyclic system which contains two bridgehead quaternary carbons that can be achieved, the chirality of which are controlled by those of the starting material, and the product stereoselectivity is only determined by the α-position of the acetylene moiety. Density functional theory calculations predicted that only the cis [3.3.0] bicyclic product could be generated, regardless of either erythro or threo substrate, which was also confirmed by experimental observations.

  6. Quantum loop subalgebra and eigenvectors of the superintegrable chiral Potts transfer matrices

    Energy Technology Data Exchange (ETDEWEB)

    Au-Yang, Helen; Perk, Jacques H H, E-mail: perk@okstate.edu, E-mail: helenperk@yahoo.com [Department of Physics, Oklahoma State University, 145 Physical Sciences, Stillwater, OK 74078-3072 (United States)

    2011-01-14

    It has been shown in earlier works that for Q = 0 and L a multiple of N, the ground state sector eigenspace of the superintegrable {tau}{sub 2}(t{sub q}) model is highly degenerate and is generated by a quantum loop algebra L(sl{sub 2}). Furthermore, this loop algebra can be decomposed into r = (N - 1)L/N simple sl{sub 2} algebras. For Q {ne} 0, we shall show here that the corresponding eigenspace of {tau}{sub 2}(t{sub q}) is still highly degenerate, but splits into two spaces, each containing 2{sup r-1} independent eigenvectors. The generators for the sl{sub 2} subalgebras, and also for the quantum loop subalgebra, are given generalizing those in the Q = 0 case. However, the Serre relations for the generators of the loop subalgebra are only proven for some states, tested on small systems and conjectured otherwise. Assuming their validity we construct the eigenvectors of the Q {ne} 0 ground state sectors for the transfer matrix of the superintegrable chiral Potts model.

  7. Transfer of chirality from adsorbed chiral molecules to the substrates highlighted by circular dichroism in angle-resolved valence photoelectron spectroscopy

    DEFF Research Database (Denmark)

    Contini, G.; Turchini, S.; Sanna, Simone

    2012-01-01

    Studies of self-assembled chiral molecules on achiral metallic surfaces have mostly focused on the determination of the geometry of adsorbates and their electronic structure. The aim of this paper is to provide direct information on the chirality character of the system and on the chirality trans...

  8. On chirality transfer in electron donor-acceptor complexes. A prediction for the sulfinimine···BF3 system.

    Science.gov (United States)

    Rode, Joanna E; Dobrowolski, Jan Cz

    2012-01-01

    Stabilization energies of the electron donor-acceptor sulfinimine···BF(3) complexes calculated at either the B3LYP/aug-cc-pVTZ or the MP2/aug-cc-pVTZ level do not allow to judge, whether the N- or O-atom in sulfinimine is stronger electron-donor to BF(3) . The problem seems to be solvable because chirality transfer phenomenon between chiral sulfinimine and achiral BF(3) is expected to be vibrational circular dichroism (VCD) active. Moreover, the bands associated with the achiral BF(3) molecule are predicted to be the most intense in the entire spectrum. However, the VCD band robustness analyses show that most of the chirality transfer modes of BF(3) are unreliable. Conversely, variation of VCD intensity with change of intermolecular distance, angle, and selected dihedrals between the complex partners shows that to establish the robustness of chirality transfer mode. It is also necessary to determine the influence of the potential energy surface (PES) shape on the VCD intensity. At the moment, there is still no universal criterion for the chirality transfer mode robustness and the conclusions formulated based on one system cannot be directly transferred even to a quite similar one. However, it is certain that more attention should be focused on relation of PES shape and the VCD mode robustness problem.

  9. Transfer hydrogenation reactions catalyzed by chiral half-sandwich Ruthenium complexes derived from Proline

    Indian Academy of Sciences (India)

    ARUN KUMAR PANDIA KUMAR; ASHOKA G SAMUELSON

    2016-09-01

    Chiral ruthenium half-sandwich complexes were prepared using a chelating diamine made from proline with a phenyl, ethyl, or benzyl group, instead of hydrogen on one of the coordinating arms. Three of these complexes were obtained as single diastereoisomers and their configuration identified by X-ray crystallography. The complexes are recyclable catalysts for the reduction of ketones to chiral alcohols in water. A ruthenium hydride species is identified as the active species by NMR spectroscopy and isotopic labelling experiments.Maximum enantio-selectivity was attained when a phenyl group was directly attached to the primary amine on the diamine ligand derived from proline.

  10. Asymmetric fluorination of α-branched cyclohexanones enabled by a combination of chiral anion phase-transfer catalysis and enamine catalysis using protected amino acids.

    Science.gov (United States)

    Yang, Xiaoyu; Phipps, Robert J; Toste, F Dean

    2014-04-09

    We report a study involving the successful merger of two separate chiral catalytic cycles: a chiral anion phase-transfer catalysis cycle to activate Selectfluor and an enamine activation cycle, using a protected amino acid as organocatalyst. We have demonstrated the viability of this approach with the direct asymmetric fluorination of α-substituted cyclohexanones to generate quaternary fluorine-containing stereocenters. With these two chiral catalytic cycles operating together in a matched sense, high enantioselectivites can be achieved, and we envisage that this dual catalysis method has the potential to be more broadly applicable, given the breadth of enamine catalysis. It also represents a rare example of chiral enamine catalysis operating successfully on α-branched ketones, substrates commonly inert to this activation mode.

  11. Spontaneous transfer of chirality in an atropisomerically enriched two-axis system.

    Science.gov (United States)

    Barrett, Kimberly T; Metrano, Anthony J; Rablen, Paul R; Miller, Scott J

    2014-05-01

    One of the most well-recognized stereogenic elements in a chiral molecule is an sp(3)-hybridized carbon atom that is connected to four different substituents. Axes of chirality can also exist about bonds with hindered barriers of rotation; molecules containing such axes are known as atropisomers. Understanding the dynamics of these systems can be useful, for example, in the design of single-atropisomer drugs or molecular switches and motors. For molecules that exhibit a single axis of chirality, rotation about that axis leads to racemization as the system reaches equilibrium. Here we report a two-axis system for which an enantioselective reaction produces four stereoisomers (two enantiomeric pairs): following a catalytic asymmetric transformation, we observe a kinetically controlled product distribution that is perturbed from the system's equilibrium position. As the system undergoes isomerization, one of the diastereomeric pairs drifts spontaneously to a higher enantiomeric ratio. In a compensatory manner, the enantiomeric ratio of the other diastereomeric pair decreases. These observations are made for a class of unsymmetrical amides that exhibits two asymmetric axes--one axis is defined through a benzamide substructure, and the other axis is associated with differentially N,N-disubstituted amides. The stereodynamics of these substrates provides an opportunity to observe a curious interplay of kinetics and thermodynamics intrinsic to a system of stereoisomers that is constrained to a situation of partial equilibrium.

  12. Reconfigurable chiroptical nanocomposites with chirality transfer from the macro- to the nanoscale

    Science.gov (United States)

    Kim, Yoonseob; Yeom, Bongjun; Arteaga, Oriol; Jo Yoo, Seung; Lee, Sang-Gil; Kim, Jin-Gyu; Kotov, Nicholas A.

    2016-04-01

    Nanostructures with chiral geometries exhibit strong polarization rotation. However, achieving reversible modulation of chirality and polarization rotation in device-friendly solid-state films is difficult for rigid materials. Here, we describe nanocomposites, made by conformally coating twisted elastic substrates with films assembled layer-by-layer from plasmonic nanocolloids, whose nanoscale geometry and rotatory optical activity can be reversibly reconfigured and cyclically modulated by macroscale stretching, with up to tenfold concomitant increases in ellipticity. We show that the chiroptical activity at 660 nm of gold nanoparticle composites is associated with circular extinction from linear effects. The polarization rotation at 550 nm originates from the chirality of nanoparticle chains with an S-like shape that exhibit a non-planar buckled geometry, with the handedness of the substrate’s macroscale twist determining the handedness of the S-like chains. Chiroptical effects at the nexus of mechanics, excitonics and plasmonics open new operational principles for optical and optoelectronic devices from nanoparticles, carbon nanotubes and other nanoscale components.

  13. Lanthanide tris(β-diketonates) as useful probes for chirality determination of biological amino alcohols in vibrational circular dichroism: ligand to ligand chirality transfer in lanthanide coordination sphere.

    Science.gov (United States)

    Miyake, Hiroyuki; Terada, Keiko; Tsukube, Hiroshi

    2014-06-01

    A series of lanthanide tris(β-diketonates) functioned as useful chirality probes in the vibrational circular dichroism (VCD) characterization of biological amino alcohols. Various chiral amino alcohols induced intense VCD signals upon ternary complexation with racemic lanthanide tris(β-diketonates). The VCD signals observed around 1500 cm(-1) (β-diketonate IR absorption region) correlated well with the stereochemistry and enantiomeric purity of the targeted amino alcohol, while the corresponding monoalcohol, monoamine, and diol substrates induced very weak VCD signals. The high-coordination number and dynamic property of the lanthanide complex offer an effective chirality VCD probing of biological substrates.

  14. Chiral Selectivity in Inter-reactant Recognition and Electron Transfer of the Oxidation of Horse Heart Cytochrome c by Trioxalatocobaltate(III).

    Science.gov (United States)

    Nazmutdinov, Renat R; Bronshtein, Michael D; Zinkicheva, Tamara T; Hansen, Niels Sthen; Zhang, Jingdong; Ulstrup, Jens

    2016-09-19

    Outer-sphere electron transfer (ET) between optically active transition-metal complexes and either other transition-metal complexes or metalloproteins is a prototype reaction for kinetic chirality. Chirality as the ratio between bimolecular rate constants of two enantiomers mostly amounts to 1.05-1.2 with either the Λ or Δ form the more reactive, but the origin of chirality in ET parameters such as work terms, electronic transmission coefficient, and nuclear reorganization free energy has not been addressed. We report a study of ET between the Λ-/Δ-[Co(Ox)3](3-) pair (Ox = oxalate) and horse heart cytochrome c (cyt c). This choice is prompted by strong ion-pair formation that enables separation into inter-reactant interaction (chiral "recognition") and ET within the ion pair ("stereoselectivity"). Chiral selectivity was first addressed experimentally. Λ-[Co(Ox)3](3-) was found to be both the more strongly bound and faster reacting enantiomer expressed respectively by the ion-pair formation constant KX and ET rate constant kET(X) (X = Λ and Δ), with KΛ/KΔ and kET(Λ)/kET(Δ) both ≈1.1-1.2. rac-[Co(Ox)3](3-) behavior is intermediate between those of Λ- and Δ-[Co(Ox)3](3-). Chirality was next analyzed by quantum-mechanical ET theory combined with density functional theory and statistical mechanical computations. We also modeled the ion pair K(+)·[Co(Ox)3](3-) in order to address the influence of the solution ionic strength. The complex structure of cyt c meant that this reactant was represented solely by the heme group including the chiral axial ligands L-His and L-Met. Both singlet and triplet hemes as well as hemes with partially deprotonated propionic acid side groups were addressed. The computations showed that the most favorable inter-reactant configuration involved a narrow distance and orientation space very close to the contact distance, substantiating the notion of a reaction complex and the equivalence of the binding constant to a bimolecular

  15. Asymmetric Transfer Hydrogenation of Prochiral Ketones in Aqueous Media with New Water-Soluble Chiral Vicinal Diamine as Ligand

    Institute of Scientific and Technical Information of China (English)

    ZHU Jin; MA Ya-Ping; LIU Hui; CHEN Li; CUI Xin; DENG Jin-Gen

    2003-01-01

    @@ As a consequence of the increasing demand for atom economy and environmental friendly methods, the water soluble ligands and their metal complexes are of great interest in catalytic synthesis because of simpler product sepa ration and the possibility of recycling. [1] Unique reactivity and selectivity are often observed in aqueous reactions. [2]Recently, we have developed a new water-soluble chiral vicinal diamine and synthesized its mono-N-tosylated derivative for the first time. The application of its mono-N-tosylated derivative in catalytic asymmetric transfer hydrogenation of prochiral ketones was examined in aqueous media. High activity (up to > 99 % conv. ) and good enatioselectivity ( up to 98% ee ) were achieved for most of prochiral aromatic ketones in organic solvent free system. [3

  16. Optically active conjugated polymer from solvent chirality transfer polymerization in monoterpenes.

    Science.gov (United States)

    Kim, Hyojin; Lee, Daehoon; Lee, Seul; Suzuki, Nozomu; Fujiki, Michiya; Lee, Chang-Lyoul; Kwak, Giseop

    2013-09-01

    Disubstituted acetylene monomers [1,2-diphenylacetylenes (DPAs: DPA-pC1, DPA-mC1, DPA-pC8); 1-phenyl-2-hexylacetylene (PHA-pC1)] are tested for asymmetric polymerization in chiral monoterpenes used as solvents and compared with the corresponding monosubstituted acetylene monomer [1-phenylacetylene (PA-pC1)]. DPA-pC1 containing a trimethylsilyl group in the para-position of the phenyl ring produces an optically active polymer with a large Cotton effect, despite the absence of a stereogenic center. The polymer sample obtained by polymerization in 87% ee (-)-α-pinene shows the strongest CD signal (gCD value at 385 nm: ∼3.2 × 10⁻³). The Cotton bands of the polymers obtained in (-)- and (+)-α-pinenes show the opposite sign in the CD signals. Theoretical calculations show that only the cis-cisoid model adopts a helical conformation. A time-correlated single photon counting experiment shows that the emission of the chiral polymer originates from a virtually single excited species with a 98% component fraction. This polymer solution does not show any significant decrease in gCD value over a wide temperature range of 20 to 80 °C. No noticeable decrease in the gCD value is detected when the polymer solution is kept at relatively low temperatures for a prolonged period (35 d). In contrast, the other polymers show no CD signal.

  17. Impact of the nature and composition of the mobile phase on the mass transfer mechanism in chiral reversed phase liquid chromatography. Application to the minimization of the solvent cost in chiral separations.

    Science.gov (United States)

    Gritti, Fabrice; Guiochon, Georges

    2014-01-31

    The mechanism of mass transfer was studied on a cellulose-based chiral stationary phase (CSP, Lux Cellulose-1) using aqueous mixtures of acetonitrile (50/50-90/10, v/v) or methanol (90/10 and 100/0, v/v) as the mobile phase. An experimental protocol validated in RPLC and HILIC chromatography and recently extended to chiral RPLC was applied. The five mass-transfer contributions (longitudinal diffusion, short-range and long-range eddy dispersion, solid-liquid mass transfer resistances due to finite intra-particle diffusivity and slow adsorption-desorption) to the reduced height equivalent to a theoretical plate (HETP) were measured. The experimental results show that the adsorption rate constants kads of trans-stilbene enantiomers onto the CSP are three times larger with acetonitrile than with methanol as the organic modifier. This is correlated to the decrease of enantioselectivity from 1.4 (in methanol) to only 1.1 (in acetonitrile). The amount of solvent needed to achieve a separation factor of exactly 2.0 was determined. This showed that analysis cost could be reduced seven times by selecting pure methanol as the eluent for a 5cm long column rather than an acetonitrile-water mixture for a longer (20-45cm) column.

  18. Enantioselective synthesis of aziridines using asymmetric transfer hydrogenation as a precursor for chiral derivatives used as bonding agent for rocket solid propellants

    Directory of Open Access Journals (Sweden)

    Aparecida M. Kawamoto

    2002-11-01

    Full Text Available A rapid, expedient and enantioselective method for the synthesis of beta-hydroxy amines and monosubstituted aziridines in up to 99% e.e., via asymmetric transfer hydrogenation of a-amino ketones and cyclisation through treatment with tosyl chloride and base, is described. (1R,2R-N-(para-toluenesulfonyl-1,2-ethylenediamine with formic acid has been utilised as a ligand for the Ruthenium (II catalysed enantioselective transfer hydrogenation of the ketones.The chiral 2-methyl aziridine, which is a potentially more efficient bonding agent for Rocket Solid Propellant has been successfully achieved.

  19. Water-Soluble Phosphine-Protected Au₁₁ Clusters: Synthesis, Electronic Structure, and Chiral Phase Transfer in a Synergistic Fashion.

    Science.gov (United States)

    Yao, Hiroshi; Iwatsu, Mana

    2016-04-05

    Synthesis of atomically precise, water-soluble phosphine-protected gold clusters is still currently limited probably due to a stability issue. We here present the synthesis, magic-number isolation, and exploration of the electronic structures as well as the asymmetric conversion of triphenylphosphine monosulfonate (TPPS)-protected gold clusters. Electrospray ionization mass spectrometry and elemental analysis result in the primary formation of Au11(TPPS)9Cl undecagold cluster compound. Magnetic circular dichroism (MCD) spectroscopy clarifies that extremely weak transitions are present in the low-energy region unresolved in the UV-vis absorption, which can be due to the Faraday B-terms based on the magnetically allowed transitions in the cluster. Asymmetric conversion without changing the nuclearity is remarkable by the chiral phase transfer in a synergistic fashion, which yields a rather small anisotropy factor (g-factor) of at most (2.5-7.0) × 10(-5). Quantum chemical calculations for model undecagold cluster compounds are then used to evaluate the optical and chiroptical responses induced by the chiral phase transfer. On this basis, we find that the Au core distortion is ignorable, and the chiral ion-pairing causes a slight increase in the CD response of the Au11 cluster.

  20. Chiral photochemistry

    CERN Document Server

    Inoue, Yoshihisa

    2004-01-01

    Direct Asymmetric Photochemistry with Circularly Polarized Light, H. RauCoherent Laser Control of the Handedness of Chiral Molecules, P. Brumer and M. ShapiroMagnetochiral Anisotropy in Asymmetric Photochemistry, G.L.J.A.RikkenEnantiodifferentiating Photosensitized Reactions, Y. InoueDiastereodifferentiating Photoreactions, N. Hoffmann and J.-P. PeteChirality in Photochromism, Y. Yokoyama and M. SaitoChiral Photochemistry with Transition Metal Complexes, S. Sakaki and T. HamadaTemplate-Induced Enantioselective Photochemical Reactions in S

  1. Asymmetric transfer hydrogenation of ketones in aqueous solution catalyzed by Rhodium(III) complexes with C2-symmetric fluorene-ligands containing chiral (1R,2R)-cyclohexane-1,2-diamine

    Energy Technology Data Exchange (ETDEWEB)

    Montalvo-Gonzalez, Ruben [Universidad Autonoma de Nayarit, Tepic, Nay (Mexico). Unidad Academica de Ciencias Quimico Biologicas y Farmaceuticas; Chavez, Daniel; Aguirre, Gerardo; Parra-Hake, Miguel; Somanathan, Ratnasamy, E-mail: somanatha@sundown.sdsu.ed [Instituto Tecnologico de Tijuana, B.C. (Mexico). Centro de Graduados e Investigacion

    2010-07-01

    Two C{sub 2}-symmetric bis(sulfonamide) ligands containing fluorene-chiral (1R, 2R)-cyclohexane-1,2-diamine were complexed to Rh{sup III}(Cp{sup *}) and used as catalyst to reduce aromatic ketones. The corresponding chiral secondary alcohols were obtained in 87-100% ee and 85-99% yield, under asymmetric transfer hydrogenation (ATH) conditions using aqueous sodium formate as the hydride source. With acetophenone, 94% ee and 86-97% yield was achieved with substrate/catalyst (S/C) ratio of 10,000. (author)

  2. Chiral superconductors.

    Science.gov (United States)

    Kallin, Catherine; Berlinsky, John

    2016-05-01

    Chiral superconductivity is a striking quantum phenomenon in which an unconventional superconductor spontaneously develops an angular momentum and lowers its free energy by eliminating nodes in the gap. It is a topologically non-trivial state and, as such, exhibits distinctive topological modes at surfaces and defects. In this paper we discuss the current theory and experimental results on chiral superconductors, focusing on two of the best-studied systems, Sr2RuO4, which is thought to be a chiral triplet p-wave superconductor, and UPt3, which has two low-temperature superconducting phases (in zero magnetic field), the lower of which is believed to be chiral triplet f-wave. Other systems that may exhibit chiral superconductivity are also discussed. Key signatures of chiral superconductivity are surface currents and chiral Majorana modes, Majorana states in vortex cores, and the possibility of half-flux quantum vortices in the case of triplet pairing. Experimental evidence for chiral superconductivity from μSR, NMR, strain, polar Kerr effect and Josephson tunneling experiments are discussed.

  3. Transfer of noncovalent chiral information along an optically inactive helical peptide chain: allosteric control of asymmetry of the C-terminal site by external molecule that binds to the N-terminal site.

    Science.gov (United States)

    Ousaka, Naoki; Inai, Yoshihito

    2009-02-20

    This study aims at demonstrating end-to-end transfer of noncovalent chiral information along a peptide chain. The domino-type induction of helical sense is proven by using achiral peptides 1-m of bis-chromophoric sequence with different chain lengths: H-(Aib-Delta(Z)Phe)(m)-(Aib-Delta(Z)Bip)(2)-Aib-OCH(3) [m = 2, 4, and 6; Aib = alpha-aminoisobutyric acid; Delta(Z)Phe = (Z)-alpha,beta-didehydrophenylalanine; Delta(Z)Bip = (Z)-beta-(4,4'-biphenyl)-alpha,beta-didehydroalanine]. They all showed the tendency to adopt a 3(10)-helix. Whereas peptide 1-m originally shows no circular dichroism (CD) signals, marked CD signals were induced at around 270-320 nm based on both the beta-aryl didehydroresidues by chiral Boc-proline (Boc = tert-butoxycarbonyl). The observed CD spectra were interpreted on the basis of the exciton chirality method and theoretical CD simulation of several helical conformations that were energy-minimized. The experimental and theoretical CD analysis reveals that Boc-l-proline induces the preference for a right-handed helicity in the whole chain of 1-m. Such noncovalent chiral induction was not observed in the corresponding N-terminally protected 1-m. Obviously, helicity induction in 1-m originates from the binding of Boc-proline to the N-terminal site. In the 17-mer (1-6), the information of helix sense reaches the 16th residue from the N-terminus. We have monitored precise transfer of noncovalent chiral stimulus along a helical peptide chain. The present study also proposes a primitive allosteric model of a single protein-mimicking backbone. Here chiral molecule binding the N-terminal site of 1-6 controls the chiroptical signals and helical sense of the C-terminal site about 30 A away.

  4. Focusing, Power Tunneling and Rejection from Chiral and/or Chiral Nihility/Nihility Metamaterials Layers

    CERN Document Server

    Shah, Syed Touseef Hussain; Syed, Aqeel A; Naqvi, Qaisar Abbas

    2013-01-01

    Focusing of electromagnetic plane wave from a large size paraboloidal reflector, composed of layers of chiral and/or chiral nihility metamaterials, has been studied us- ing Maslov's method. First, the transmission and reflection of electromagnetic plane wave from two parallel layers of chiral and/or chiral nihility metamaterials are cal- culated using transfer matrix method. The effects of change of angle of incidence, chirality parameters and impedances of layers are noted and discussed. Special cases by taking very large and small values of permittivity of second layer, while assuming value of corresponding chirality equal to zero, are also treated. These special cases are equivalent to reflection from a perfect electric conductor backed chiral layer and nihility backed chiral layer, respectively. Results of reflection from parallel layers have been utilized to study focusing from a large size paraboloidal reflector. The present study, on focusing from a paraboloidal re{\\deg}ector, not only unifies several ...

  5. Isotopic chirality

    Energy Technology Data Exchange (ETDEWEB)

    Floss, H.G. [Univ. of Washington, Seattle, WA (United States)

    1994-12-01

    This paper deals with compounds that are chiral-at least in part, due to isotope substitution-and their use in tracing the steric course of enzyme reaction in vitro and in vivo. There are other applications of isotopically chiral compounds (for example, in analyzing the steric course of nonenzymatic reactions and in probing the conformation of biomolecules) that are important but they will not be discussed in this context.

  6. Chiral memory via chiral amplification and selective depolymerization of porphyrin aggregates.

    Science.gov (United States)

    Helmich, Floris; Lee, Cameron C; Schenning, Albertus P H J; Meijer, E W

    2010-12-01

    Chiral memory at the supramolecular level is obtained via a new approach using chiral Zn porphrins and achiral Cu porphyrins. In a "sergeant-and-soldiers" experiment, the Zn "sergeant" transfers its own chirality to Cu "soldiers" and, after chiral amplification, the "sergeant" is removed from the coaggregates by axial ligation with a Lewis base. After this extraction, the preferred helicity observed for the aggregates containing achiral Cu porphyrins reveals a chiral memory effect that is stable and can be erased and partially restored upon subsequent heating and cooling.

  7. Isonitrile iron(II) complexes with chiral N2P2 macrocycles in the enantioselective transfer hydrogenation of ketones.

    Science.gov (United States)

    Bigler, Raphael; Mezzetti, Antonio

    2014-12-19

    Bis(isonitrile) iron(II) complexes bearing a C2-symmetric N2P2 macrocyclic ligand, which are easily prepared from the corresponding bis(acetonitrile) analogue, catalyze the asymmetric transfer hydrogenation (ATH) of a broad scope of ketones in excellent yields (up to 98%) and with high enantioselectivity (up to 91% ee).

  8. Chiral Nanoscience and Nanotechnology

    OpenAIRE

    Dibyendu S. Bag; T.C. Shami; K.U. Bhasker Rao

    2008-01-01

    The paper reviews nanoscale science and technology of chiral molecules/macromolecules-under twosubtopics-chiral nanotechnology and nano-chiral technology. Chiral nanotechnology discusses thenanotechnology, where molecular chirality plays a role in the properties of materials, including molecularswitches, molecular motors, and other molecular devices; chiral supramolecules and self-assembled nanotubesand their functions are also highlighted. Nano-chiral technology  describes the nanoscale appr...

  9. Spatial control of chirality in supramolecular aggregates.

    Science.gov (United States)

    Castriciano, Maria A; Gentili, Denis; Romeo, Andrea; Cavallini, Massimiliano; Scolaro, Luigi Monsù

    2017-03-09

    Chirality is one of the most intriguing properties of matter related to a molecule's lack of mirror symmetry. The transmission of chirality from the molecular level up to the macroscopic scale has major implications in life sciences but it is also relevant for many chemical applications ranging from catalysis to spintronic. These technological applications require an accurate control of morphology, homogeneity and chiral handedness of thin films and nanostructures. We demonstrate a simple approach to specifically transfer chirality to the model supramolecular system of J aggregates of the protonated form of tetrakis(4-sulfonatophenyl)-porphyrin by utilizing a soft lithography technique. This approach successfully allows the fabrication of an ordered distribution of sub-micrometric structures in precise and controllable positions with programmed chirality, providing a fundamental breakthrough toward the exploitation of chiral supramolecular aggregates in technological applications, such as sensors, non-linear optics and spintronic.

  10. Spatial control of chirality in supramolecular aggregates

    Science.gov (United States)

    Castriciano, Maria A.; Gentili, Denis; Romeo, Andrea; Cavallini, Massimiliano; Scolaro, Luigi Monsù

    2017-01-01

    Chirality is one of the most intriguing properties of matter related to a molecule’s lack of mirror symmetry. The transmission of chirality from the molecular level up to the macroscopic scale has major implications in life sciences but it is also relevant for many chemical applications ranging from catalysis to spintronic. These technological applications require an accurate control of morphology, homogeneity and chiral handedness of thin films and nanostructures. We demonstrate a simple approach to specifically transfer chirality to the model supramolecular system of J aggregates of the protonated form of tetrakis(4-sulfonatophenyl)-porphyrin by utilizing a soft lithography technique. This approach successfully allows the fabrication of an ordered distribution of sub-micrometric structures in precise and controllable positions with programmed chirality, providing a fundamental breakthrough toward the exploitation of chiral supramolecular aggregates in technological applications, such as sensors, non-linear optics and spintronic. PMID:28275239

  11. On Chiral Space Groups and Chiral Molecules

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    This note explains the relationship (as well as the absence of a relationship) between chiral space groups and chiral molecules (which have absolute configurations). For a chiral molecule, which must crystallize in a chiral space group, the outcome of the absolute configuration determination must be linked to some other properties of the chiral crystal such as its optical activity for the observation to the relevant.

  12. On Chiral Space Groups and Chiral Molecules

    Institute of Scientific and Technical Information of China (English)

    NgSeikWng; HUSheng-Zhi

    2003-01-01

    This note explains the relationship (as well as the absence of a relationship) between chiral space groups and chiral molecules (which have absolute configurations).For a chiral molecule,which must crystallize in a chiral space group,the outcome of the absolute configuration determination must be linked to some other properties of the chiral crystal such as its optical activity for the observation to the relevant.

  13. Stegosaurus chirality

    OpenAIRE

    Cameron, R.P.; Cameron, J. A.; Barnett, S. M.

    2016-01-01

    We explain that Stegosaurus exhibited exterior chirality and observe that the largest plate in particular of USNM 4394, USNM 4714, DMNS 2818 and NHMUK R36730 appears to have tilted to the right rather than to the left in each case. Several instances in which Stegosaurus specimens have been confused with their distinct, hypothetical mirror-image forms are highlighted. We believe our findings to be consistent with the hypothesis that Stegosaurus's plates acted primarily as display structures. A...

  14. New Chiral Metal Cluster Systems for Catalytic Asymmetric Syntheses of Chiral Alcohols

    Institute of Scientific and Technical Information of China (English)

    LI Yan-yun; CHEN Jian-shan; YANG Chuan-bo; DONG Zhen-rong; LI Bao-zhu; ZHANG Hui; GAO Jing-xing; TAKAO Ikariya

    2004-01-01

    The efficient chiral Ru3(CO)12 systems were prepared in situ from Ru3(CO)12 and various chiral diiminoor diamino-diphosphine tetradentate ligands. The systems have been used for the asymmetric transfer hydrogenation of propiophenone in 2-propanol, leading to 1-phenyl-1-propanol in a 98% yield and 96% e.e. The IR study suggests that the carbonyl hydride anion [HRu3(CO)11]- most probably exists as a principal species under the reaction conditions. The high chiral efficiency may be due to the synergetic effect produced by the neighboring ruthenium atoms and a special chiral micro-environment involving the polydentate ligand and the Ru3 framework.

  15. Chiral Nanoscience and Nanotechnology

    Directory of Open Access Journals (Sweden)

    Dibyendu S. Bag

    2008-09-01

    Full Text Available The paper reviews nanoscale science and technology of chiral molecules/macromolecules-under twosubtopics-chiral nanotechnology and nano-chiral technology. Chiral nanotechnology discusses thenanotechnology, where molecular chirality plays a role in the properties of materials, including molecularswitches, molecular motors, and other molecular devices; chiral supramolecules and self-assembled nanotubesand their functions are also highlighted. Nano-chiral technology  describes the nanoscale approaches to chiraltechnology such as asymmetric synthesis and catalysis, chiral separation and detection, and enantiomericanalysis. Chiral sensors have also been included. The state-of-the-art chiral research at DMSRDE,Kanpur isalso presented.Defence Science Journal, 2008, 58(5, pp.626-635, DOI:http://dx.doi.org/10.14429/dsj.58.1685

  16. Chiral mirrors

    Energy Technology Data Exchange (ETDEWEB)

    Plum, Eric, E-mail: erp@orc.soton.ac.uk [Optoelectronics Research Centre and Centre for Photonic Metamaterials, University of Southampton, Highfield, Southampton SO17 1BJ (United Kingdom); Zheludev, Nikolay I., E-mail: niz@orc.soton.ac.uk [Optoelectronics Research Centre and Centre for Photonic Metamaterials, University of Southampton, Highfield, Southampton SO17 1BJ (United Kingdom); The Photonics Institute and Centre for Disruptive Photonic Technologies, Nanyang Technological University, Singapore 637378 (Singapore)

    2015-06-01

    Mirrors are used in telescopes, microscopes, photo cameras, lasers, satellite dishes, and everywhere else, where redirection of electromagnetic radiation is required making them arguably the most important optical component. While conventional isotropic mirrors will reflect linear polarizations without change, the handedness of circularly polarized waves is reversed upon reflection. Here, we demonstrate a type of mirror reflecting one circular polarization without changing its handedness, while absorbing the other. The polarization-preserving mirror consists of a planar metasurface with a subwavelength pattern that cannot be superimposed with its mirror image without being lifted out of its plane, and a conventional mirror spaced by a fraction of the wavelength from the metasurface. Such mirrors enable circularly polarized lasers and Fabry-Pérot cavities with enhanced tunability, gyroscopic applications, polarization-sensitive detectors of electromagnetic waves, and can be used to enhance spectroscopies of chiral media.

  17. Detecting, visualizing, and measuring gold nanoparticle chirality using helical pitch measurements in nematic liquid crystal phases.

    Science.gov (United States)

    Sharma, Anshul; Mori, Taizo; Lee, Huey-Charn; Worden, Matthew; Bidwell, Eric; Hegmann, Torsten

    2014-12-23

    Chirality at the nanoscale, or more precisely, the chirality or chiroptical effects of chiral ligand-capped metal nanoparticles (NPs) is an intriguing and rapidly evolving field in nanomaterial research with promising applications in catalysis, metamaterials, and chiral sensing. The aim of this work was to seek out a system that not only allows the detection and understanding of NP chirality but also permits visualization of the extent of chirality transfer to a surrounding medium. The nematic liquid crystal phase is an ideal candidate, displaying characteristic defect texture changes upon doping with chiral additives. To test this, we synthesized chiral cholesterol-capped gold NPs and prepared well-dispersed mixtures in two nematic liquid crystal hosts. Induced circular dichroism spectropolarimetry and polarized light optical microscopy revealed that all three gold NPs induce chiral nematic phases, and that those synthesized in the presence of a chiral bias (disulfide) are more powerful chiral inducers than those where the NP was formed in the absence of a chiral bias (prepared by conjugation of a chiral silane to preformed NPs). Helical pitch data here visually show a clear dependence on the NP size and the number of chiral ligands bound to the NP surface, thereby supporting earlier experimental and theoretical data that smaller metal NPs made in the presence of a chiral bias are stronger chiral inducers.

  18. Molecular chirality at surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Ernst, Karl-Heinz [Empa, Swiss Federal Laboratories for Materials Science and Technology, Ueberlandstrasse 129, 8600 Duebendorf (Switzerland); Organic Chemistry Institute, University Zurich, 8057 Zuerich (Switzerland)

    2012-11-15

    With the adsorption of larger molecules being increasingly tackled by surface scientists, the aspect of chirality often plays a role. This paper gives a topical review of molecular chirality at surfaces and gives a phenomenological overview of different aspects of adsorption and self-assembly of chiral and prochiral molecules and the principles of mirror-symmetry breaking at a surface. After a brief introduction into the history of molecular chirality and the important role it played for understanding the spatial structure of molecules, definitions of chirality are presented. Topics treated here are principle ways to create single chiral adsorbates, chiral ensembles, and monolayers by achiral molecules, adsorption of intrinsically chiral molecules at achiral and chiral surfaces, long-range symmetry breaking in two-dimensional (2D) crystals due to additional chiral bias, chiral restructuring of solid surfaces under the influence of chiral molecules, switching the handedness of adsorbates, and chirality at the liquid/air interface. An outlook onto further potential research directions and recommendations for further reading, including nonsurface-related sources of chiral topics completes this paper. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  19. Chiral dynamics of baryons in the perturbative chiral quark model

    Energy Technology Data Exchange (ETDEWEB)

    Pumsa-ard, K.

    2006-07-01

    In this work we develop and apply variants of a perturbative chiral quark model (PCQM) to the study of baryonic properties dominantly in the low-energy region. In a first step we consider a noncovariant form of the PCQM, where confinement is modelled by a static, effective potential and chiral corrections are treated to second order, in line with similar chiral quark models. We apply the PCQM to the study of the electromagnetic form factors of the baryon octet. We focus in particular on the low-energy observables such as the magnetic moments, the charge and magnetic radii. In addition, the electromagnetic N-delta transition is also studied in the framework of the PCQM. In the chiral loop calculations we consider a quark propagator, which is restricted to the quark ground state, or in hadronic language to nucleon and delta intermediate states, for simplicity. We furthermore include the low-lying excited states to the quark propagator. In particular, the charge radius of the neutron and the transverse helicity amplitudes of the N-delta transition are considerably improved by this additional effect. In a next step we develop a manifestly Lorentz covariant version of the PCQM, where in addition higher order chiral corrections are included. The full chiral quark Lagrangian is motivated by and in analogy to the one of Chiral Perturbation Theory (ChPT). This Lagrangian contains a set of low energy constants (LECs), which are parameters encoding short distance effects and heavy degrees of freedom. We evaluate the chiral Lagrangian to order O(p{sup 4}) and to one loop to generate the dressing of the bare quark operators by pseudoscalar mesons. In addition we include the vector meson degrees of freedom in our study. Projection of the dressed quark operators on the baryonic level serves to calculate the relevant matrix elements. In a first application of this scheme, we resort to a parameterization of the valence quark form factors in the electromagnetic sector. Constraints

  20. Chiral conducting polymers.

    Science.gov (United States)

    Kane-Maguire, Leon A P; Wallace, Gordon G

    2010-07-01

    This critical review describes the preparation and properties of a relatively new class of chiral macromolecules, namely chiral conducting polymers. It focuses in particular on examples based on polypyrrole, polythiophene and polyaniline. They possess remarkable properties, combining not only chirality with electrical conductivity but also the ability to undergo facile redox and pH switching. These unique properties have opened up a range of exciting new potential applications, including as chiral sensors, as novel stationary phases for chiral separations, and as chiral electrodes for electrochemical asymmetric synthesis (153 references).

  1. Deracemization of bilirubin as the marker of the chirality of micellar aggregates.

    Science.gov (United States)

    Sorrenti, Alessandro; Altieri, Barbara; Ceccacci, Francesca; Di Profio, Pietro; Germani, Raimondo; Giansanti, Luisa; Savelli, Gianfranco; Mancini, Giovanna

    2012-01-01

    The deracemization of bilirubin in micellar aggregates of structurally correlated chiral surfactants was studied by circular dichroism experiments and exploited as the marker of the expression of chirality of the aggregates. The obtained results suggest that the hydrophobic interactions control the transfer of chirality from the monomers to the aggregates, and that different regions of the same aggregate might feature opposite enantiorecognition capabilities.

  2. Reflection and transmission coefficients of multiple chiral layers

    Institute of Scientific and Technical Information of China (English)

    SABAH Cumali; UCKUN Savas

    2006-01-01

    This paper presents a general analysis of reflection and transmission coefficients of multiple chiral layers in detail. Reflection and transmission coefficients through multiple chiral layers are computed and presented particularly for the incident wave of parallel polarization for a number of cases-a wide range of incidence angle, neigh- boring center frequency and different chirality parameters. Transfer matrix method is used in the analysis. From the numerical results, it can be seen that multiple chiral layers may be used as a polarization-conversion transmission filter and antireflection filter at the frequency band around the central frequency.

  3. Baryons and Chiral Symmetry

    CERN Document Server

    Liu, Keh-Fei

    2016-01-01

    The relevance of chiral symmetry in baryons is highlighted in three examples in the nucleon spectroscopy and structure. The first one is the importance of chiral dynamics in understanding the Roper resonance. The second one is the role of chiral symmetry in the lattice calculation of $\\pi N \\sigma$ term and strangeness. The third one is the role of chiral $U(1)$ anomaly in the anomalous Ward identity in evaluating the quark spin and the quark orbital angular momentum. Finally, the chiral effective theory for baryons is discussed.

  4. Chiral Rotational Spectroscopy

    CERN Document Server

    Cameron, Robert P; Barnett, Stephen M

    2015-01-01

    We introduce chiral rotational spectroscopy: a new technique that enables the determination of the individual optical activity polarisability components $G_{XX}'$, $G_{YY}'$, $G_{ZZ}'$, $A_{X,YZ}$, $A_{Y,ZX}$ and $A_{Z,XY}$ of chiral molecules, in a manner that reveals the enantiomeric constitution of a sample whilst yielding an incisive signal even for a racemate. Chiral rotational spectroscopy could find particular use in the analysis of molecules that are chiral by virtue of their isotopic constitution and molecules with multiple chiral centres. The principles that underpin chiral rotational spectroscopy can also be exploited in the search for molecular chirality in space, which, if found, may add weight to hypotheses that biological homochirality and indeed life itself are of cosmic origin.

  5. On chiral and non chiral 1D supermultiplets

    Energy Technology Data Exchange (ETDEWEB)

    Toppan, Francesco, E-mail: toppan@cbpf.b [Centro Brasileiro de Pesquisas Fisicas (TEO/CBPF), Rio de Janeiro, RJ (Brazil). Coordenacao de Fisica Teorica

    2011-07-01

    In this talk I discuss and clarify some issues concerning chiral and non chiral properties of the one-dimensional supermultiplets of the N-extended supersymmetry. Quaternionic chirality can be defined for N = 4, 5, 6, 7, 8. Octonionic chirality for N = 8 and beyond. Inequivalent chiralities only arise when considering several copies of N = 4 or N = 8 supermultiplets. (author)

  6. Chiral symmetry and chiral-symmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Peskin, M.E.

    1982-12-01

    These lectures concern the dynamics of fermions in strong interaction with gauge fields. Systems of fermions coupled by gauge forces have a very rich structure of global symmetries, which are called chiral symmetries. These lectures will focus on the realization of chiral symmetries and the causes and consequences of thier spontaneous breaking. A brief introduction to the basic formalism and concepts of chiral symmetry breaking is given, then some explicit calculations of chiral symmetry breaking in gauge theories are given, treating first parity-invariant and then chiral models. These calculations are meant to be illustrative rather than accurate; they make use of unjustified mathematical approximations which serve to make the physics more clear. Some formal constraints on chiral symmetry breaking are discussed which illuminate and extend the results of our more explicit analysis. Finally, a brief review of the phenomenological theory of chiral symmetry breaking is presented, and some applications of this theory to problems in weak-interaction physics are discussed. (WHK)

  7. Extrinsic electromagnetic chirality in metamaterials

    OpenAIRE

    Plum, E.; Fedotov, V. A.; Zheludev, N. I.

    2009-01-01

    Three- and two-dimensional chirality arising from the mutual orientation of non-chiral planar metamaterial structures and the incident electromagnetic wave (extrinsic chirality) lead to pronounced optical activity, circular dichroism and asymmetric transmission indistinguishable from those seen in media consisting of three- and two-dimensionally chiral molecules (intrinsic chirality).

  8. Chirality in thiolate-protected gold clusters.

    Science.gov (United States)

    Knoppe, Stefan; Bürgi, Thomas

    2014-04-15

    Over recent years, research on thiolate-protected gold clusters Au(m)(SR)n has gained significant interest. Milestones were the successful determination of a series of crystal structures (Au102(SR)44, Au25(SR)18, Au38(SR)24, Au36(SR)24, and Au28(SR)20). For Au102(SR)44, Au38(SR)24, and Au28(SR)20, intrinsic chirality was found. Strong Cotton effects (circular dichroism, CD) of gold clusters protected by chiral ligands have been reported a long time ago, indicating the transfer of chiral information from the ligand into the cluster core. Our lab has done extensive studies on chiral thiolate-protected gold clusters, including those protected with chiral ligands. We demonstrated that vibrational circular dichroism can serve as a useful tool for the determination of conformation of the ligand on the surface of the cluster. The first reports on crystal structures of Au102(SR)44 and Au38(SR)24 revealed the intrinsic chirality of these clusters. Their chirality mainly arises from the arrangement of the ligands on the surface of the cluster cores. As achiral ligands are used to stabilize the clusters, racemic mixtures are obtained. However, the separation of the enantiomers by HPLC was demonstrated which enabled the measurement of their CD spectra. Thermally induced inversion allows determination of the activation parameters for their racemization. The inversion demonstrates that the gold-thiolate interface is anything but fixed; in contrast, it is rather flexible. This result is of fundamental interest and needs to be considered in future applications. A second line of our research is the selective introduction of chiral, bidentate ligands into the ligand layer of intrinsically chiral gold clusters. The ligand exchange reaction is highly diastereoselective. The bidentate ligand connects two of the protecting units on the cluster surface and thus effectively stabilizes the cluster against thermally induced inversion. A minor (but significant) influence of chiral ligands to

  9. Chirality and chiroptical properties of amyloid fibrils.

    Science.gov (United States)

    Dzwolak, Wojciech

    2014-09-01

    Chirality of amyloid fibrils-linear beta-sheet-rich aggregates of misfolded protein chains-often manifests in morphological traits such as helical twist visible in atomic force microscopy and in chiroptical properties accessible to vibrational circular dichroism (VCD). According to recent studies the relationship between molecular chirality of polypeptide building blocks and superstructural chirality of amyloid fibrils may be more intricate and less deterministic than previously assumed. Several puzzling experimental findings have put into question earlier intuitive ideas on: 1) the bottom-up chirality transfer upon amyloidogenic self-assembly, and 2) the structural origins of chiroptical properties of protein aggregates. For example, removal of a single amino acid residue from an amyloidogenic all-L peptide was shown to reverse handedness of fibrils. On the other hand, certain types of amyloid aggregates revealed surprisingly strong VCD spectra with the sign and shape dependent on the conditions of fibrillation. Hence, microscopic and chiroptical studies have highlighted chirality as one more aspect of polymorphism of amyloid fibrils. This brief review is intended to outline the current state of research on amyloid-like fibrils from the perspective of their structural and superstructural chirality and chiroptical properties.

  10. Chiral rotational spectroscopy

    Science.gov (United States)

    Cameron, Robert P.; Götte, Jörg B.; Barnett, Stephen M.

    2016-09-01

    We introduce chiral rotational spectroscopy, a technique that enables the determination of the orientated optical activity pseudotensor components BX X, BY Y, and BZ Z of chiral molecules, in a manner that reveals the enantiomeric constitution of a sample and provides an incisive signal even for a racemate. Chiral rotational spectroscopy could find particular use in the analysis of molecules that are chiral solely by virtue of their isotopic constitution and molecules with multiple chiral centers. A basic design for a chiral rotational spectrometer together with a model of its functionality is given. Our proposed technique offers the more familiar polarizability components αX X, αY Y, and αZ Z as by-products, which could see it find use even for achiral molecules.

  11. Chiral Superfluidity for QCD

    CERN Document Server

    Kalaydzhyan, Tigran

    2014-01-01

    We argue that the strongly coupled quark-gluon plasma formed at LHC and RHIC can be considered as a chiral superfluid. The "normal" component of the fluid is the thermalized matter in common sense, while the "superfluid" part consists of long wavelength (chiral) fermionic states moving independently. We use the bosonization procedure with a finite cut-off and obtain a dynamical axion-like field out of the chiral fermionic modes. Then we use relativistic hydrodynamics for macroscopic description of the effective theory obtained after the bosonization. Finally, solving the hydrodynamic equations in gradient expansion, we find that in the presence of external electromagnetic fields or rotation the motion of the "superfluid" component gives rise to the chiral magnetic, chiral vortical, chiral electric and dipole wave effects. Latter two effects are specific for a two-component fluid, which provides us with crucial experimental tests of the model.

  12. Emerging chirality in nanoscience.

    Science.gov (United States)

    Wang, Yong; Xu, Jun; Wang, Yawen; Chen, Hongyu

    2013-04-07

    Chirality in nanoscience may offer new opportunities for applications beyond the traditional fields of chirality, such as the asymmetric catalysts in the molecular world and the chiral propellers in the macroscopic world. In the last two decades, there has been an amazing array of chiral nanostructures reported in the literature. This review aims to explore and categorize the common mechanisms underlying these systems. We start by analyzing the origin of chirality in simple systems such as the helical spring and hair vortex. Then, the chiral nanostructures in the literature were categorized according to their material composition and underlying mechanism. Special attention is paid to highlight systems with original discoveries, exceptional structural characteristics, or unique mechanisms.

  13. Magnetic fields and chiral asymmetry in the early hot universe

    Science.gov (United States)

    Sydorenko, Maksym; Tomalak, Oleksandr; Shtanov, Yuri

    2016-10-01

    In this paper, we study analytically the process of external generation and subsequent free evolution of the lepton chiral asymmetry and helical magnetic fields in the early hot universe. This process is known to be affected by the Abelian anomaly of the electroweak gauge interactions. As a consequence, chiral asymmetry in the fermion distribution generates magnetic fields of non-zero helicity, and vice versa. We take into account the presence of thermal bath, which serves as a seed for the development of instability in magnetic field in the presence of externally generated lepton chiral asymmetry. The developed helical magnetic field and lepton chiral asymmetry support each other, considerably prolonging their mutual existence, in the process of `inverse cascade' transferring magnetic-field power from small to large spatial scales. For cosmologically interesting initial conditions, the chiral asymmetry and the energy density of helical magnetic field are shown to evolve by scaling laws, effectively depending on a single combined variable. In this case, the late-time asymptotics of the conformal chiral chemical potential reproduces the universal scaling law previously found in the literature for the system under consideration. This regime is terminated at lower temperatures because of scattering of electrons with chirality change, which exponentially washes out chiral asymmetry. We derive an expression for the termination temperature as a function of the chiral asymmetry and energy density of helical magnetic field.

  14. Chiral atomically thin films

    Science.gov (United States)

    Kim, Cheol-Joo; Sánchez-Castillo, A.; Ziegler, Zack; Ogawa, Yui; Noguez, Cecilia; Park, Jiwoong

    2016-06-01

    Chiral materials possess left- and right-handed counterparts linked by mirror symmetry. These materials are useful for advanced applications in polarization optics, stereochemistry and spintronics. In particular, the realization of spatially uniform chiral films with atomic-scale control of their handedness could provide a powerful means for developing nanodevices with novel chiral properties. However, previous approaches based on natural or grown films, or arrays of fabricated building blocks, could not offer a direct means to program intrinsic chiral properties of the film on the atomic scale. Here, we report a chiral stacking approach, where two-dimensional materials are positioned layer-by-layer with precise control of the interlayer rotation (θ) and polarity, resulting in tunable chiral properties of the final stack. Using this method, we produce left- and right-handed bilayer graphene, that is, a two-atom-thick chiral film. The film displays one of the highest intrinsic ellipticity values (6.5 deg μm-1) ever reported, and a remarkably strong circular dichroism (CD) with the peak energy and sign tuned by θ and polarity. We show that these chiral properties originate from the large in-plane magnetic moment associated with the interlayer optical transition. Furthermore, we show that we can program the chiral properties of atomically thin films layer-by-layer by producing three-layer graphene films with structurally controlled CD spectra.

  15. Chiral Shock Waves

    CERN Document Server

    Sen, Srimoyee

    2016-01-01

    We study shock waves in relativistic chiral matter. We argue that the conventional Rankine- Hugoinot relations are modified due to the presence of chiral transport phenomena. We show that the entropy discontinuity in a weak shock wave is linearly proportional to the pressure discontinuity when the effect of chiral transport becomes sufficiently large. We also show that rarefaction shock waves, which do not exist in usual nonchiral fluids, can appear in chiral matter. These features are exemplified by shock propagation in dense neutrino matter in the hydrodynamic regime.

  16. Anomalous chiral superfluidity

    Energy Technology Data Exchange (ETDEWEB)

    Lublinsky, Michael, E-mail: lublinsky@phys.uconn.ed [Department of Physics and Astronomy, Stony Brook University, Stony Brook, NY 11794 (United States); Physics Department, Ben-Gurion University, Beer Sheva 84105 (Israel); Zahed, Ismail [Department of Physics and Astronomy, Stony Brook University, Stony Brook, NY 11794 (United States)

    2010-02-08

    We discuss both the anomalous Cartan currents and the energy-momentum tensor in a left chiral theory with flavor anomalies as an effective theory for flavored chiral phonons in a chiral superfluid with the gauged Wess-Zumino-Witten term. In the mean-field (leading tadpole) approximation the anomalous Cartan currents and the energy-momentum tensor take the form of constitutive currents in the chiral superfluid state. The pertinence of higher order corrections and the Adler-Bardeen theorem is briefly noted.

  17. Doped Chiral Polymer Metamaterials Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Doped Chiral Polymer Metamaterials (DCPM) with tunable resonance frequencies have been developed by adding plasmonic inclusions into chiral polymers with variable...

  18. Applications of chiral symmetry

    CERN Document Server

    Pisarski, R D

    1995-01-01

    I discuss several topics in the applications of chiral symmetry at nonzero temperature, including: where the rho goes, disoriented chiral condensates, and the phase diagram for QCD with 2+1 flavors. (Based upon talks presented at the "Workshop on Finite Temperature QCD", Wuhan, P.R.C., April, 1994.)

  19. From helical to planar chirality by on-surface chemistry.

    Science.gov (United States)

    Stetsovych, Oleksandr; Švec, Martin; Vacek, Jaroslav; Chocholoušová, Jana Vacek; Jančařík, Andrej; Rybáček, Jiří; Kosmider, Krzysztof; Stará, Irena G; Jelínek, Pavel; Starý, Ivo

    2017-03-01

    The chirality of molecular structures is paramount in many phenomena, including enantioselective reactions, molecular self-assembly, biological processes and light or electron-spin polarization. Flat prochiral molecules, which are achiral in the gas phase or solution, can exhibit adsorption-induced chirality when deposited on surfaces. The whole array of such molecular adsorbates is naturally racemic as spontaneous global mirror-symmetry breaking is disfavoured. Here we demonstrate a chemical method of obtaining flat prochiral molecules adsorbed on the solid achiral surface in such a way that a specific adsorbate handedness globally dominates. An optically pure helical precursor is flattened in a cascade of on-surface reactions, which enables chirality transfer. The individual reaction products are identified by high-resolution scanning-probe microscopy. The ultimate formation of globally non-racemic assemblies of flat molecules through stereocontrolled on-surface synthesis allows for chirality to be expressed in as yet unexplored types of organic-inorganic chiral interfaces.

  20. From helical to planar chirality by on-surface chemistry

    Science.gov (United States)

    Stetsovych, Oleksandr; Švec, Martin; Vacek, Jaroslav; Chocholoušová, Jana Vacek; Jančařík, Andrej; Rybáček, Jiří; Kosmider, Krzysztof; Stará, Irena G.; Jelínek, Pavel; Starý, Ivo

    2016-11-01

    The chirality of molecular structures is paramount in many phenomena, including enantioselective reactions, molecular self-assembly, biological processes and light or electron-spin polarization. Flat prochiral molecules, which are achiral in the gas phase or solution, can exhibit adsorption-induced chirality when deposited on surfaces. The whole array of such molecular adsorbates is naturally racemic as spontaneous global mirror-symmetry breaking is disfavoured. Here we demonstrate a chemical method of obtaining flat prochiral molecules adsorbed on the solid achiral surface in such a way that a specific adsorbate handedness globally dominates. An optically pure helical precursor is flattened in a cascade of on-surface reactions, which enables chirality transfer. The individual reaction products are identified by high-resolution scanning-probe microscopy. The ultimate formation of globally non-racemic assemblies of flat molecules through stereocontrolled on-surface synthesis allows for chirality to be expressed in as yet unexplored types of organic-inorganic chiral interfaces.

  1. Magnetic fields and chiral asymmetry in the early hot universe

    CERN Document Server

    Sidorenko, Maxim; Shtanov, Yuri

    2016-01-01

    In this paper, we study analytically the process of external generation and subsequent free evolution of the lepton chiral asymmetry and helical magnetic fields in the early hot universe. This process is known to be affected by the Abelian anomaly of the electroweak gauge interactions. As a consequence, chiral asymmetry in the fermion distribution generates magnetic fields of non-zero helicity, and vice versa. We take into account the presence of thermal bath, which serves as a seed for the development of instability in magnetic field in the presence of externally generated lepton chiral asymmetry. The developed helical magnetic field and lepton chiral asymmetry support each other, considerably prolonging their mutual existence, in the process of 'inverse cascade' transferring magnetic-field power from small to large spatial scales. For cosmologically interesting initial conditions, the chiral asymmetry and the energy density of helical magnetic field are shown to evolve by scaling laws, effectively depending...

  2. Helical Ordering in Chiral Block Copolymers

    Science.gov (United States)

    Zhao, Wei; Hong, Sung Woo; Chen, Dian; Grason, Gregory; Russell, Thomas

    2012-02-01

    Introducing molecular chirality into the segments of block copolymers can influence the nature of the resultant morphology. Such an effect was found for poly(styrene-b-L-lactide) (PS-b-PLLA) diblock copolymers where hexagonally packed PLLA helical microdomains (H* phase) form in a PS matrix. However, molecular ordering of PLLA within the helical microdomains and the transfer of chirality from the segmental level to the mesoscale is still not well understood. We developed a field theoretic model to describe the interactions between segments of chiral blocks, which have the tendency to form a ``cholesteric'' texture. Based on the model, we calculated the bulk morphologies of chiral AB diblock copolymers using self-consistent field theory (SCFT). Experiments show that the H* phase only forms when microphase separation between PS and PLLA block happens first and crystallization of PLLA block is suppressed or happens within confined microdomain. Hence, crystalline ordering is not necessary for H* phase formation. The SCFT offers the chance to explore the range of thermodynamic stability of helical structures in the phase diagram of chiral block copolymer melts, by tuning parameters not only like the block segregation strength and composition, but also new parameters such as the ratio between preferred helical pitch to the radius of gyration and the Frank elastic constant for inter-segment distortions.

  3. Geometrical approach to central molecular chirality: a chirality selection rule

    OpenAIRE

    Capozziello, S.; Lattanzi, A

    2004-01-01

    Chirality is of primary importance in many areas of chemistry and has been extensively investigated since its discovery. We introduce here the description of central chirality for tetrahedral molecules using a geometrical approach based on complex numbers. According to this representation, for a molecule having n chiral centres, it is possible to define an index of chirality. Consequently a chirality selection rule has been derived which allows the characterization of a molecule as achiral, e...

  4. Molecular model for chirality phenomena.

    Science.gov (United States)

    Latinwo, Folarin; Stillinger, Frank H; Debenedetti, Pablo G

    2016-10-21

    Chirality is a hallmark feature for molecular recognition in biology and chemical physics. We present a three-dimensional continuum model for studying chirality phenomena in condensed phases using molecular simulations. Our model system is based upon a simple four-site molecule and incorporates non-trivial kinetic behavior, including the ability to switch chirality or racemize, as well as thermodynamics arising from an energetic preference for specific chiral interactions. In particular, we introduce a chiral renormalization parameter that can locally favor either homochiral or heterochiral configurations. Using this model, we explore a range of chirality-specific phenomena, including the kinetics of chiral inversion, the mechanism of spontaneous chiral symmetry breaking in the liquid, chirally driven liquid-liquid phase separation, and chiral crystal structures.

  5. Applications of chiral symmetry

    Energy Technology Data Exchange (ETDEWEB)

    Pisarski, R.D.

    1995-03-01

    The author discusses several topics in the applications of chiral symmetry at nonzero temperature. First, where does the rho go? The answer: up. The restoration of chiral symmetry at a temperature T{sub {chi}} implies that the {rho} and a{sub 1} vector mesons are degenerate in mass. In a gauged linear sigma model the {rho} mass increases with temperature, m{sub {rho}}(T{sub {chi}}) > m{sub {rho}}(0). The author conjectures that at T{sub {chi}} the thermal {rho} - a{sub 1}, peak is relatively high, at about {approximately}1 GeV, with a width approximately that at zero temperature (up to standard kinematic factors). The {omega} meson also increases in mass, nearly degenerate with the {rho}, but its width grows dramatically with temperature, increasing to at least {approximately}100 MeV by T{sub {chi}}. The author also stresses how utterly remarkable the principle of vector meson dominance is, when viewed from the modern perspective of the renormalization group. Secondly, he discusses the possible appearance of disoriented chiral condensates from {open_quotes}quenched{close_quotes} heavy ion collisions. It appears difficult to obtain large domains of disoriented chiral condensates in the standard two flavor model. This leads to the last topic, which is the phase diagram for QCD with three flavors, and its proximity to the chiral critical point. QCD may be very near this chiral critical point, and one might thereby generated large domains of disoriented chiral condensates.

  6. Theory of ion-chirality relation in ferroelectric liquid crystals

    Science.gov (United States)

    Lahiri, T.; Pal Majumder, T.

    2012-04-01

    The presence of impurity ions in ferroelectric liquid crystals (FLC) could produce a significant impact on the chirality of the medium with a possible modification in the polarization profile of the system. We theoretically observed these possibilities by considering an in-plane and bulk free energy density for the sample. Based on a suitable chirality transfer formalism, we explained the role of impurity ions in altering the chiral nature of a FLC medium. A continuous transition from modulated phases to uniform phases is also predicted within the framework of this theory. Then, we investigated the possible modification in the polarization profile driven by ionic impurities.

  7. Quantum-mechanical picture of peripheral chiral dynamics

    CERN Document Server

    Granados, C

    2015-01-01

    The nucleon's peripheral transverse charge and magnetization densities are computed in chiral effective field theory. The densities are represented in first-quantized form, as overlap integrals of chiral light-front wave functions describing the transition of the nucleon to soft pion-nucleon intermediate states. The orbital motion of the pion causes a large left-right asymmetry in a transversely polarized nucleon. The effect attests to the relativistic nature of chiral dynamics [pion momenta k = O(M_pi)] and could be observed in form factor measurements at low momentum transfer.

  8. Quantum-mechanical picture of peripheral chiral dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Granados, Carlos [Uppsala Univ., Uppsala (Sweden); Weiss, Christian [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)

    2015-08-28

    The nucleon's peripheral transverse charge and magnetization densities are computed in chiral effective field theory. The densities are represented in first-quantized form, as overlap integrals of chiral light-front wave functions describing the transition of the nucleon to soft pion-nucleon intermediate states. The orbital motion of the pion causes a large left-right asymmetry in a transversely polarized nucleon. As a result, the effect attests to the relativistic nature of chiral dynamics [pion momenta k = O(Mπ)] and could be observed in form factor measurements at low momentum transfer.

  9. Spectral signatures of chirality

    DEFF Research Database (Denmark)

    Pedersen, Jesper Goor; Mortensen, Asger

    2009-01-01

    We present a new way of measuring chirality, via the spectral shift of photonic band gaps in one-dimensional structures. We derive an explicit mapping of the problem of oblique incidence of circularly polarized light on a chiral one-dimensional photonic crystal with negligible index contrast...... to the formally equivalent problem of linearly polarized light incident on-axis on a non-chiral structure with index contrast. We derive analytical expressions for the first-order shifts of the band gaps for negligible index contrast. These are modified to give good approximations to the band gap shifts also...

  10. Chiral supergravity and anomalies

    CERN Document Server

    Mielke, E W; Macias, Alfredo; Mielke, Eckehard W.

    1999-01-01

    Similarily as in the Ashtekar approach, the translational Chern-Simons term is, as a generating function, instrumental for a chiral reformulation of simple (N=1) supergravity. After applying the algebraic Cartan relation between spin and torsion, the resulting canonical transformation induces not only decomposition of the gravitational fields into selfdual and antiselfdual modes, but also a splitting of the Rarita-Schwinger fields into their chiral parts in a natural way. In some detail, we also analyze the consequences for axial and chiral anomalies.

  11. Hyperon decay form factors in chiral perturbation theory

    CERN Document Server

    Lacour, Andre; Meißner, Ulf-G

    2007-01-01

    We present a complete calculation of the SU(3)-breaking corrections to the hyperon vector form factors up to O(p^4) in covariant baryon chiral perturbation theory. Partial higher-order contributions are obtained, and we discuss chiral extrapolations of the vector form factor at zero momentum transfer. In addition we derive low-energy theorems for the subleading moments in hyperon decays, the weak Dirac radii and the weak anomalous magnetic moments, up to O(p^4).

  12. Catalysis of Dynamical Chiral Symmetry Breaking by Chiral Chemical Potential

    CERN Document Server

    Braguta, V V

    2016-01-01

    In this paper we study the properties of media with chiral imbalance parameterized by chiral chemical potential. It is shown that depending on the strength of interaction between constituents in the media the chiral chemical potential either creates or enhances dynamical chiral symmetry breaking. Thus the chiral chemical potential plays a role of the catalyst of dynamical chiral symmetry breaking. Physically this effect results from the appearance of the Fermi surface and additional fermion states on this surface which take part in dynamical chiral symmetry breaking. An interesting conclusion which can be drawn is that at sufficiently small temperature chiral plasma is unstable with respect to condensation of Cooper pairs and dynamical chiral symmetry breaking even for vanishingly small interactions between constituents.

  13. Chiral Brownian heat pump

    OpenAIRE

    Van Den Broek, Martijn; Van Den Broeck, Christian

    2007-01-01

    We present the exact analysis of a chiral Brownian motor and heat pump. Optimization of the construction predicts, for a nanoscale device, frequencies of the order of kHz and cooling rates of the order of femtojoule per second.

  14. Chiral brownian heat pump.

    Science.gov (United States)

    van den Broek, M; Van den Broeck, C

    2008-04-04

    We present the exact analysis of a chiral Brownian motor and heat pump. Optimization of the construction predicts, for a nanoscale device, frequencies of the order of kHz and cooling rates of the order of femtojoule per second.

  15. Color chiral solitons

    CERN Document Server

    Novozhilov, V Yu; Novozhilov, Victor; Novozhilov, Yuri

    2002-01-01

    We discuss specific features of color chiral solitons (asymptotics, possibility of confainment, quantization) at example of isolated SU(2) color skyrmions, i.e. skyrmions in a background field which is the vacuum field forming the gluon condensate.

  16. Electrodynamics of chiral matter

    Science.gov (United States)

    Qiu, Zebin; Cao, Gaoqing; Huang, Xu-Guang

    2017-02-01

    Many-body systems with chiral fermions can exhibit novel transport phenomena that violate parity and time-reversal symmetries, such as the chiral magnetic effect, the anomalous Hall effect, and the anomalous generation of charge. Based on the Maxwell-Chern-Simons electrodynamics, we examine some electromagnetic and optical properties of such systems including the electrostatics, the magnetostatics, the propagation of electromagnetic waves, the novel optical effects, etc.

  17. Chiral Odd GPDs

    Directory of Open Access Journals (Sweden)

    Goldstein Gary R.

    2015-01-01

    Full Text Available Nucleon spin structure, transversity and the tensor charge are of central importance to understanding the role of QCD in hadronic physics. A new approach to measuring orbital angular momenta of quarks in the proton via twist 3 GPDs is shown. The “flexible parametrization” of chiral even GPDs is reviewed and its transformation into the chiral odd sector is discussed. The resulting parametrization is applied to recent data on π0 and η electroproduction.

  18. Axially chiral imidodiphosphoric Acid catalyst for asymmetric sulfoxidation reaction: insights on asymmetric induction.

    Science.gov (United States)

    Jindal, Garima; Sunoj, Raghavan B

    2014-04-22

    Insights into chiral induction for an asymmetric sulfoxidation reaction involving a single oxygen atom transfer are gained through analyzing the stereocontrolling transition states. The fitting of the substrate into the chiral cavity of a new class of imidodiphosphoric Brønsted acids, as well as weak CH⋅⋅⋅π and CH⋅⋅⋅O noncovalent interactions, are identified as responsible for the observed chiral induction.

  19. Spontaneous transmission of chirality through multiple length scales.

    Science.gov (United States)

    Iski, Erin V; Tierney, Heather L; Jewell, April D; Sykes, E Charles H

    2011-06-20

    The hierarchical transfer of chirality in nature, from the nano-, to meso-, to macroscopic length scales, is very complex, and as of yet, not well understood. The advent of scanning probes has allowed chirality to be monitored at the single molecule or monolayer level and has opened up the possibility to track enantiospecific interactions and chiral self-assembly with molecular-scale detail. This paper describes the self-assembly of a simple, model molecule (naphtho[2,3-a]pyrene) that is achiral in the gas phase, but becomes chiral when adsorbed on a surface. This polyaromatic hydrocarbon forms a stable and reversibly ordered system on Cu(111) in which the transmission of chirality from single surface-bound molecules to complex 2D chiral architectures can be monitored as a function of molecular packing density and surface temperature. In addition to the point chirality of the surface-bound molecule, the unit cell of the molecular domains was also found to be chiral due to the incommensurate alignment of the molecular rows with respect to the underlying metal lattice. These molecular domains always aggregated in groups of three, all of the same chirality, but with different rotational orientations, forming homochiral "tri-lobe" ensembles. At a larger length scale, these tri-lobe ensembles associated with nearest-neighbor tri-lobe units of opposite chirality at lower packing densities before forming an extended array of homochiral tri-lobe ensembles at higher converges. This system displayed chirality at a variety of size scales from the molecular (≈1 nm) and domain (≈5 nm) to the tri-lobe ensemble (≈10 nm) and extended array (>25 nm) levels. The chirality of the tri-lobe ensembles dictated how the overall surface packing occurred and both homo- and heterochiral arrays could be reproducibly and reversibly formed and interchanged as a function of surface coverage. Finally, these chirally templated surfaces displayed remarkable enantiospecificity for

  20. Opportunities Offered by Chiral η6-Arene/N-Arylsulfonyl-diamine-RuII Catalysts in the Asymmetric Transfer Hydrogenation of Ketones and Imines

    Directory of Open Access Journals (Sweden)

    Libor Červený

    2011-06-01

    Full Text Available Methods for the asymmetric transfer hydrogenation (ATH of ketones and imines are still being intensively studied and developed. Of foremost interest is the use of Noyori’s [RuCl(η6-arene(N-TsDPEN] complexes in the presence of a hydrogen donor (i-PrOH, formic acid. These complexes have found numerous practical applications and have been extensively modified. The resulting derivatives have been heterogenized, used in ATH in water or ionic liquids and even some attempts have been made to approach the properties of biocatalysts. Therefore, an appropriate modification of the catalyst that suits the specific requirements for the reaction conditions is very often readily available. The mechanism of the reaction has also been explored to a great extent. Model substrates, acetophenone (a ketone and 6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline (an imine, are both reduced by this Ru catalytic system with almost perfect selectivity. However, in each case the major product is a different enantiomer (S- for an alcohol, R- for an amine when the S,S-catalyst is used, which demanded an in-depth mechanistic investigation. Full-scale molecular modelling of this system enabled us to visualize the plausible 3D structures of the transition states, allowing the proposition of a viable explanation of previous experimental findings.

  1. Chiral Random Matrix Theory and Chiral Perturbation Theory

    CERN Document Server

    Damgaard, P H

    2011-01-01

    Spontaneous breaking of chiral symmetry in QCD has traditionally been inferred indirectly through low-energy theorems and comparison with experiments. Thanks to the understanding of an unexpected connection between chiral Random Matrix Theory and chiral Perturbation Theory, the spontaneous breaking of chiral symmetry in QCD can now be shown unequivocally from first principles and lattice simulations. In these lectures I give an introduction to the subject, starting with an elementary discussion of spontaneous breaking of global symmetries.

  2. Chiral Random Matrix Theory and Chiral Perturbation Theory

    Energy Technology Data Exchange (ETDEWEB)

    Damgaard, Poul H, E-mail: phdamg@nbi.dk [Niels Bohr International Academy and Discovery Center, The Niels Bohr Institute, Blegdamsvej 17, DK-2100 Copenhagen (Denmark)

    2011-04-01

    Spontaneous breaking of chiral symmetry in QCD has traditionally been inferred indirectly through low-energy theorems and comparison with experiments. Thanks to the understanding of an unexpected connection between chiral Random Matrix Theory and chiral Perturbation Theory, the spontaneous breaking of chiral symmetry in QCD can now be shown unequivocally from first principles and lattice simulations. In these lectures I give an introduction to the subject, starting with an elementary discussion of spontaneous breaking of global symmetries.

  3. Chiral Graphene Quantum Dots.

    Science.gov (United States)

    Suzuki, Nozomu; Wang, Yichun; Elvati, Paolo; Qu, Zhi-Bei; Kim, Kyoungwon; Jiang, Shuang; Baumeister, Elizabeth; Lee, Jaewook; Yeom, Bongjun; Bahng, Joong Hwan; Lee, Jaebeom; Violi, Angela; Kotov, Nicholas A

    2016-02-23

    Chiral nanostructures from metals and semiconductors attract wide interest as components for polarization-enabled optoelectronic devices. Similarly to other fields of nanotechnology, graphene-based materials can greatly enrich physical and chemical phenomena associated with optical and electronic properties of chiral nanostructures and facilitate their applications in biology as well as other areas. Here, we report that covalent attachment of l/d-cysteine moieties to the edges of graphene quantum dots (GQDs) leads to their helical buckling due to chiral interactions at the "crowded" edges. Circular dichroism (CD) spectra of the GQDs revealed bands at ca. 210-220 and 250-265 nm that changed their signs for different chirality of the cysteine edge ligands. The high-energy chiroptical peaks at 210-220 nm correspond to the hybridized molecular orbitals involving the chiral center of amino acids and atoms of graphene edges. Diverse experimental and modeling data, including density functional theory calculations of CD spectra with probabilistic distribution of GQD isomers, indicate that the band at 250-265 nm originates from the three-dimensional twisting of the graphene sheet and can be attributed to the chiral excitonic transitions. The positive and negative low-energy CD bands correspond to the left and right helicity of GQDs, respectively. Exposure of liver HepG2 cells to L/D-GQDs reveals their general biocompatibility and a noticeable difference in the toxicity of the stereoisomers. Molecular dynamics simulations demonstrated that d-GQDs have a stronger tendency to accumulate within the cellular membrane than L-GQDs. Emergence of nanoscale chirality in GQDs decorated with biomolecules is expected to be a general stereochemical phenomenon for flexible sheets of nanomaterials.

  4. Superconductivity in a chiral nanotube

    Science.gov (United States)

    Qin, F.; Shi, W.; Ideue, T.; Yoshida, M.; Zak, A.; Tenne, R.; Kikitsu, T.; Inoue, D.; Hashizume, D.; Iwasa, Y.

    2017-02-01

    Chirality of materials are known to affect optical, magnetic and electric properties, causing a variety of nontrivial phenomena such as circular dichiroism for chiral molecules, magnetic Skyrmions in chiral magnets and nonreciprocal carrier transport in chiral conductors. On the other hand, effect of chirality on superconducting transport has not been known. Here we report the nonreciprocity of superconductivity--unambiguous evidence of superconductivity reflecting chiral structure in which the forward and backward supercurrent flows are not equivalent because of inversion symmetry breaking. Such superconductivity is realized via ionic gating in individual chiral nanotubes of tungsten disulfide. The nonreciprocal signal is significantly enhanced in the superconducting state, being associated with unprecedented quantum Little-Parks oscillations originating from the interference of supercurrent along the circumference of the nanotube. The present results indicate that the nonreciprocity is a viable approach toward the superconductors with chiral or noncentrosymmetric structures.

  5. Chiral anomalies and differential geometry

    Energy Technology Data Exchange (ETDEWEB)

    Zumino, B.

    1983-10-01

    Some properties of chiral anomalies are described from a geometric point of view. Topics include chiral anomalies and differential forms, transformation properties of the anomalies, identification and use of the anomalies, and normalization of the anomalies. 22 references. (WHK)

  6. Quarkyonic Chiral Spirals

    CERN Document Server

    Kojo, Toru; McLerran, Larry; Pisarski, Robert D

    2009-01-01

    We consider the formation of chiral density waves in Quarkyonic matter, which is a phase where cold, dense quarks experience confining forces. We model confinement following Gribov and Zwanziger, taking the gluon propagator, in Coulomb gauge and momentum space, as 1/(p^2)^2. We assume that the number of colors, N, is large, and that the quark chemical potential, mu, is much larger than renormalization mass scale, Lambda_QCD. To leading order in 1/N and Lambda_QCD, a gauge theory with Nf flavors of massless quarks in 3+1 dimensions naturally reduces to a gauge theory in 1+1 dimensions, with an enlarged flavor symmetry of SU(2Nf). Through an anomalous chiral rotation, in two dimensions a Fermi sea of massless quarks maps directly onto the corresponding theory in vacuum. A chiral condensate forms locally, and varies with the spatial position, z, as . Following Schon and Thies, we term this two dimensional pion condensate a (Quarkyonic) chiral spiral. Massive quarks also exhibit chiral spirals, with the magnitude...

  7. Chiral Synthons in Pesticide Syntheses

    NARCIS (Netherlands)

    Feringa, Bernard

    1988-01-01

    The use of chiral synthons in the preparation of enantiomerically pure pesticides is described in this chapter. Several routes to chiral synthons based on asymmetric synthesis or on natural products are illustrated. Important sources of chiral building blocks are reviewed. Furthermore the implicatio

  8. Chiral fermions on the lattice

    CERN Document Server

    Jahn, O; Jahn, Oliver; Pawlowski, Jan M.

    2002-01-01

    We discuss topological obstructions to putting chiral fermions on an even dimensional lattice. The setting includes Ginsparg-Wilson fermions, but is more general. We prove a theorem which relates the total chirality to the difference of generalised winding numbers of chiral projection operators. For an odd number of Weyl fermions this implies that particles and anti-particles live in topologically different spaces.

  9. [Chirality and drugs].

    Science.gov (United States)

    Testa, B; Reist, M; Carrupt, P A

    2000-07-01

    The two enantiomers of a chiral drug may have vastly different pharmacodynamic and pharmacokinetic properties. As a result, the research and development of chiral drugs raises specific problems some of which are discussed here. Thus, various pharmacokinetic interactions may involve two enantiomers, as seen for example when one enantiomer inhibits the metabolism of the other and modifies its effects. A different situation occurs when a third compound stereoselectively inhibits the metabolism of one of the two enantiomers. Another problem examined here results from the lack of configurational stability of some chiral drugs, a little known phenomenon whose consequences can be of pharmacological or pharmaceutical significance depending on the rate of the reaction of racemization or epimerisation. In-depth investigations are needed before choosing between a eutomer or a racemate.

  10. Doped Chiral Polymer Metamaterials

    Science.gov (United States)

    Park, Cheol (Inventor); Kang, Jin Ho (Inventor); Gordon, Keith L. (Inventor); Sauti, Godfrey (Inventor); Lowther, Sharon E. (Inventor); Bryant, Robert G. (Inventor)

    2017-01-01

    Some implementations provide a composite material that includes a first material and a second material. In some implementations, the composite material is a metamaterial. The first material includes a chiral polymer (e.g., crystalline chiral helical polymer, poly-.gamma.-benzyl-L-glutamate (PBLG), poly-L-lactic acid (PLA), polypeptide, and/or polyacetylene). The second material is within the chiral polymer. The first material and the second material are configured to provide an effective index of refraction value for the composite material of 1 or less. In some implementations, the effective index of refraction value for the composite material is negative. In some implementations, the effective index of refraction value for the composite material of 1 or less is at least in a wavelength of one of at least a visible spectrum, an infrared spectrum, a microwave spectrum, and/or an ultraviolet spectrum.

  11. Chiral Quantum Optics

    CERN Document Server

    Lodahl, Peter; Stobbe, Søren; Schneeweiss, Philipp; Volz, Jürgen; Rauschenbeutel, Arno; Pichler, Hannes; Zoller, Peter

    2016-01-01

    At the most fundamental level, the interaction between light and matter is manifested by the emission and absorption of single photons by single quantum emitters. Controlling light--matter interaction is the basis for diverse applications ranging from light technology to quantum--information processing. Many of these applications are nowadays based on photonic nanostructures strongly benefitting from their scalability and integrability. The confinement of light in such nanostructures imposes an inherent link between the local polarization and propagation direction of light. This leads to {\\em chiral light--matter interaction}, i.e., the emission and absorption of photons depend on the propagation direction and local polarization of light as well as the polarization of the emitter transition. The burgeoning research field of {\\em chiral quantum optics} offers fundamentally new functionalities and applications both for single emitters and ensembles thereof. For instance, a chiral light--matter interface enables...

  12. Chiral quark model

    Indian Academy of Sciences (India)

    H Weigel

    2003-11-01

    In this talk I review studies of hadron properties in bosonized chiral quark models for the quark flavor dynamics. Mesons are constructed from Bethe–Salpeter equations and baryons emerge as chiral solitons. Such models require regularization and I show that the two-fold Pauli–Villars regularization scheme not only fully regularizes the effective action but also leads the scaling laws for structure functions. For the nucleon structure functions the present approach serves to determine the regularization prescription for structure functions whose leading moments are not given by matrix elements of local operators. Some numerical results are presented for the spin structure functions.

  13. Interweaving Chiral Spirals

    CERN Document Server

    Kojo, Toru; Fukushima, Kenji; McLerran, Larry; Pisarski, Robert D

    2011-01-01

    We elaborate how to construct the interweaving chiral spirals in (2+1) dimensions, that is defined as a superposition of differently oriented chiral spirals. We divide the two-dimensional Fermi sea into distinct wedges characterized by the opening angle 2 Theta and the depth Q \\simeq pF, where pF is the Fermi momentum. Each wedge earns an energy gain by forming a single chiral spiral. The optimal values for Theta and Q are chosen by the balance between this energy gain and the energy costs from the deformed Fermi surface (dominant at large Theta) and patch-patch interactions (dominant at small Theta). We estimate these energy gains and costs by means of the expansions in terms of 1/Nc, Lambda_QCD/Q, and Theta using a non-local four-Fermi interaction model: At small 1/Nc the mass gap (chiral condensate) is large enough and the interaction among quarks and the condensate is local in momentum space thanks to the form factor in our non-local model. The fact that patch-patch interactions lie only near the patch bo...

  14. Simplicial chiral models

    CERN Document Server

    Rossi, P; Rossi, Paolo; Tan, Chung I

    1995-01-01

    Principal chiral models on a d-1 dimensional simplex are introduced and studied analytically in the large N limit. The d = 0 , 2, 4 and \\infty models are explicitly solved. Relationship with standard lattice models and with few-matrix systems in the double scaling limit are discussed.

  15. Chiral magnetic effect without chirality source in asymmetric Weyl semimetals

    CERN Document Server

    Kharzeev, Dmitri; Meyer, Rene

    2016-01-01

    We describe a new type of the Chiral Magnetic Effect (CME) that should occur in Weyl semimetals with an asymmetry in the dispersion relations of the left- and right-handed chiral Weyl fermions. In such materials, time-dependent pumping of electrons from a non-chiral external source generates a non-vanishing chiral chemical potential. This is due to the different capacities of the left- and right-handed (LH and RH) chiral Weyl cones arising from the difference in the density of states in the LH and RH cones. The chiral chemical potential then generates, via the chiral anomaly, a current along the direction of an applied magnetic field even in the absence of an external electric field. The source of chirality imbalance in this new setup is thus due to the band structure of the system and the presence of (non-chiral) electron source, and not due to the parallel electric and magnetic fields. We illustrate the effect by an argument based on the effective field theory, and by the chiral kinetic theory calculation f...

  16. A VCD robust mode analysis of induced chirality: the case of pulegone in chloroform.

    Science.gov (United States)

    Nicu, Valentin Paul; Debie, Elke; Herrebout, Wouter; Van der Veken, Benjamin; Bultinck, Patrick; Baerends, Evert Jan

    2009-01-01

    Vibrational modes in an achiral molecule may acquire rotational strength by complexation to a chiral molecule, as happens for achiral solvent molecules complexed to a chiral solute. We investigate this transfer of chirality in vibrational circular dichroism for the pulegone molecule in CDCl(3) solvent from the point of view of the robustness concept introduced recently. It turns out that the transfer of chirality yields nonrobust modes, which means that, although they are observed in vibrational circular dichroism (VCD) experiments, the sign of these modes cannot be predicted reliably with standard (Density Functional Theory) VCD calculations. This limits the usefulness of the induced chirality phenomenon for obtaining information on the intermolecular interactions that give rise to it.

  17. Detecting the chirality for coupled quantum dots

    Energy Technology Data Exchange (ETDEWEB)

    Cao Huijuan [Institute for Condensed Matter Physics, School of Physics and Telecommunication Engineering, South China Normal University, Guangzhou 510631 (China); Hu Lian [Institute for Condensed Matter Physics, School of Physics and Telecommunication Engineering, South China Normal University, Guangzhou 510631 (China)], E-mail: huliancaohj@yahoo.com

    2008-04-21

    We propose a scheme to detect the chirality for a system consisting of three coupled quantum dots. The chirality is found to be determined by the frequency of the transition between chiral states under the chiral symmetry broken perturbation. The results are important to construct quantum gates and to demonstrate chiral entangle states in the triangle spin dots.

  18. Soldering Chiralities; 2, Non-Abelian Case

    CERN Document Server

    Wotzasek, C

    1996-01-01

    We study the non-abelian extension of the soldering process of two chiral WZW models of opposite chiralities, resulting in a (non-chiral) WZW model living in a 2D space-time with non trivial Riemanian curvature.

  19. Spiral Galaxies as Chiral Objects?

    CERN Document Server

    Capozziello, S; Capozziello, Salvatore; Lattanzi, Alessandra

    2005-01-01

    Spiral galaxies show axial symmetry and an intrinsic 2D-chirality. Environmental effects can influence the chirality of originally isolated stellar systems and a progressive loss of chirality can be recognised in the Hubble sequence. We point out a preferential modality for genetic galaxies as in microscopic systems like aminoacids, sugars or neutrinos. This feature could be the remnant of a primordial symmetry breaking characterizing systems at all scales.

  20. Intrinsic Chirality of CdSe/ZnS Quantum Dots and Quantum Rods.

    Science.gov (United States)

    Mukhina, Maria V; Maslov, Vladimir G; Baranov, Alexander V; Fedorov, Anatoly V; Orlova, Anna O; Purcell-Milton, Finn; Govan, Joseph; Gun'ko, Yurii K

    2015-05-13

    A new class of chiral nanoparticles is of great interest not only for nanotechnology, but also for many other fields of scientific endeavor. Normally the chirality in semiconductor nanocrystals is induced by the initial presence of chiral ligands/stabilizer molecules. Here we report intrinsic chirality of ZnS coated CdSe quantum dots (QDs) and quantum rods (QRs) stabilized by achiral ligands. As-prepared ensembles of these nanocrystals have been found to be a racemic mixture of d- and l-nanocrystals which also includes a portion of nonchiral nanocrystals and so in total the solution does not show a circular dichroism (CD) signal. We have developed a new enantioselective phase transfer technique to separate chiral nanocrystals using an appropriate chiral ligand and obtain optically active ensembles of CdSe/ZnS QDs and QRs. After enantioselective phase transfer, the nanocrystals isolated in organic phase, still capped with achiral ligands, now display circular dichroism (CD). We propose that the intrinsic chirality of CdSe/ZnS nanocrystals is caused by the presence of naturally occurring chiral defects.

  1. Chiral Biomarkers in Meteorites

    Science.gov (United States)

    Hoover, Richard B.

    2010-01-01

    The chirality of organic molecules with the asymmetric location of group radicals was discovered in 1848 by Louis Pasteur during his investigations of the rotation of the plane of polarization of light by crystals of sodium ammonium paratartrate. It is well established that the amino acids in proteins are exclusively Levorotary (L-aminos) and the sugars in DNA and RNA are Dextrorotary (D-sugars). This phenomenon of homochirality of biological polymers is a fundamental property of all life known on Earth. Furthermore, abiotic production mechanisms typically yield recemic mixtures (i.e. equal amounts of the two enantiomers). When amino acids were first detected in carbonaceous meteorites, it was concluded that they were racemates. This conclusion was taken as evidence that they were extraterrestrial and produced by abiologically. Subsequent studies by numerous researchers have revealed that many of the amino acids in carbonaceous meteorites exhibit a significant L-excess. The observed chirality is much greater than that produced by any currently known abiotic processes (e.g. Linearly polarized light from neutron stars; Circularly polarized ultraviolet light from faint stars; optically active quartz powders; inclusion polymerization in clay minerals; Vester-Ulbricht hypothesis of parity violations, etc.). This paper compares the measured chirality detected in the amino acids of carbonaceous meteorites with the effect of these diverse abiotic processes. IT is concluded that the levels observed are inconsistent with post-arrival biological contamination or with any of the currently known abiotic production mechanisms. However, they are consistent with ancient biological processes on the meteorite parent body. This paper will consider these chiral biomarkers in view of the detection of possible microfossils found in the Orgueil and Murchison carbonaceous meteorites. Energy dispersive x-ray spectroscopy (EDS) data obtained on these morphological biomarkers will be

  2. Free-standing chiral plasmonics

    Science.gov (United States)

    Leong, Eunice Sok Ping; Deng, Jie; Wu, Siji; Khoo, Eng Huat; Liu, Yan Jun

    2014-11-01

    Chiral plasmonic nanostructures offer the ability to achieve strong optical circular dichroism (CD) activity over a broad spectral range, which has been challenging for chiral molecules. Chiral plasmonic nanostructures have been extensively studied based on top-down and bottom-up fabrication techniques. Particularly, in the top-down electron-beam lithography, 3D plasmonic nanostructure fabrication involves layer-by-layer patterning and complex alignment, which is time-consuming and causes many defects in the structures. Here, we present a free-standing 3D chiral plamonic nanostructures using the electron-beam lithography technique with much simplified fabrication processes. The 3D chiral plasmonic nanostructures consist of a free-standing ultrathin silicon nitride membrane with well-aligned L-shape metal nanostructures on one side and disk-shape ones on the other side. The free-standing membrane provides an ultra-smooth metal/dielectric interface and uniformly defines the gap between the upper and lower layers in an array of chiral nanostructures. Such free-standing chiral plasmonic nanostructures exhibit strong CD at optical frequencies, which can be engineered by simply changing the disk size on one side of the membrane. Experimental results are in good agreement with the finite-difference time-domain simulations. Such free-standing chiral plasmonics holds great potential for chirality analysis of biomolecules, drugs, and chemicals.

  3. Chiral nuclear thermodynamics

    CERN Document Server

    Fiorilla, Salvatore; Weise, Wolfram

    2011-01-01

    We calculate the equation of state of nuclear matter for arbitrary isospin-asymmetry up to three loop order in the free energy density in the framework of in-medium chiral perturbation theory. In our approach 1\\pi- and 2\\pi-exchange dynamics with the inclusion of the \\Delta-isobar excitation as an explicit degree of freedom, corresponding to the long- and intermediate-range correlations, are treated explicitly. Few contact terms fixed to reproduce selected known properties of nuclear matter encode the short-distance physics. Two-body as well as three-body forces are systematically included. We find a critical temperature of about 15 MeV for symmetric nuclear matter. We investigate the dependence of the liquid-gas first-order phase transition on isospin-asymmetry. In the same chiral framework we calculate the chiral condensate of isospin-symmetric nuclear matter at finite temperatures. The contribution of the \\Delta-isobar excitation is essential for stabilizing the condensate. As a result, we find no indicati...

  4. Generalized simplicial chiral models

    CERN Document Server

    Alimohammadi, M

    2000-01-01

    Using the auxiliary field representation of the simplicial chiral models on a (d-1)-dimensional simplex, we generalize the simplicial chiral models by replacing the term Tr$(AA^{\\d})$ in the Lagrangian of these models, by an arbitrary class function of $AA^{\\d}; V(AA^{\\d})$. This is the same method that has been used in defining the generalized two-dimensional Yang-Mills theories (gYM_2) from ordinary YM_2. We call these models, the " generalized simplicial chiral models ". With the help of the results of one-link integral over a U(N) matrix, we compute the large-N saddle-point equations for eigenvalue density function $\\ro (z)$ in the weak ($\\b >\\b_c$) and strong ($\\b <\\b_c$) regions. In d=2, where the model somehow relates to gYM_2 theory, we solve the saddle-point equations and find $\\ro (z)$ in two region, and calculate the explicit value of critical point $\\b_c$ for $V(B)=TrB^n (B=AA^{\\d})$. For $V(B)=Tr B^2,Tr B^3$ and Tr$B^4$, we study the critical behaviour of the model at d=2, and by calculating t...

  5. Amplification of Chirality through Self-Replication of Micellar Aggregates in Water

    KAUST Repository

    Bukhriakov, Konstantin

    2015-03-17

    We describe a system in which the self-replication of micellar aggregates results in a spontaneous amplification of chirality in the reaction products. In this system, amphiphiles are synthesized from two "clickable" fragments: a water-soluble "head" and a hydrophobic "tail". Under biphasic conditions, the reaction is autocatalytic, as aggregates facilitate the transfer of hydrophobic molecules to the aqueous phase. When chiral, partially enantioenriched surfactant heads are used, a strong nonlinear induction of chirality in the reaction products is observed. Preseeding the reaction mixture with an amphiphile of one chirality results in the amplification of this product and therefore information transfer between generations of self-replicating aggregates. Because our amphiphiles are capable of catalysis, information transfer, and self-assembly into bounded structures, they present a plausible model for prenucleic acid "lipid world" entities. © 2015 American Chemical Society.

  6. Chiral nanophotonics chiral optical properties of plasmonic systems

    CERN Document Server

    Schäferling, Martin

    2017-01-01

    This book describes the physics behind the optical properties of plasmonic nanostructures focusing on chiral aspects. It explains in detail how the geometry determines chiral near-fields and how to tailor their shape and strength. Electromagnetic fields with strong optical chirality interact strongly with chiral molecules and, therefore, can be used for enhancing the sensitivity of chiroptical spectroscopy techniques. Besides a short review of the latest results in the field of plasmonically enhanced enantiomer discrimination, this book introduces the concept of chiral plasmonic near-field sources for enhanced chiroptical spectroscopy. The discussion of the fundamental properties of these light sources provides the theoretical basis for further optimizations and is of interest for researchers at the intersection of nano-optics, plasmonics and stereochemistry. .

  7. Isothermal Titration Calorimetry of Chiral Polymeric Nanoparticles.

    Science.gov (United States)

    Werber, Liora; Preiss, Laura C; Landfester, Katharina; Muñoz-Espí, Rafael; Mastai, Yitzhak

    2015-09-01

    Chiral polymeric nanoparticles are of prime importance, mainly due to their enantioselective potential, for many applications such as catalysis and chiral separation in chromatography. In this article we report on the preparation of chiral polymeric nanoparticles by miniemulsion polymerization. In addition, we describe the use of isothermal titration calorimetry (ITC) to measure the chiral interactions and the energetics of the adsorption of enantiomers from aqueous solutions onto chiral polymeric nanoparticles. The characterization of chirality in nano-systems is a very challenging task; here, we demonstrate that ITC can be used to accurately determine the thermodynamic parameters associated with the chiral interactions of nanoparticles. The use of ITC to measure the energetics of chiral interactions and recognition at the surfaces of chiral nanoparticles can be applied to other nanoscale chiral systems and can provide further insight into the chiral discrimination processes of nanomaterials.

  8. Chiral Dynamics 2006

    Science.gov (United States)

    Ahmed, Mohammad W.; Gao, Haiyan; Weller, Henry R.; Holstein, Barry

    2007-10-01

    pt. A. Plenary session. Opening remarks: experimental tests of chiral symmetry breaking / A. M. Bernstein. [Double pie symbols] scattering / H. Leutwyler. Chiral effective field theory in a [Triangle]-resonance region / V. Pascalutsa. Some recent developments in chiral perturbation theory / Ulf-G. Mei ner. Chiral extrapolation and nucleon structure from the lattice / R.D. Young. Recent results from HAPPEX / R. Michaels. Chiral symmetries and low energy searches for new physics / M.J. Ramsey-Musolf. Kaon physics: recent experimental progress / M. Moulson. Status of the Cabibbo angle / V. Cirigliano. Lattice QCD and nucleon spin structure / J.W. Negele. Spin sum rules and polarizabilities: results from Jefferson lab / J-P Chen. Compton scattering and nucleon polarisabilities / Judith A. McGovern. Virtual compton scattering at MIT-bates / R. Miskimen. Physics results from the BLAST detector at the BATES accelerator / R.P. Redwine. The [Pie sympbol]NN system, recent progress / C. Hanhart. Application of chiral nuclear forces to light nuclei / A. Nogga. New results on few-body experiments at low energy / Y. Nagai. Few-body lattice calculations / M.J. Savage. Research opportunities at the upgraded HI?S facility / H.R. Weller -- pt. B. Goldstone boson dynamics. Working group summary: Goldstone Boson dynamics / G. Colangelo and S. Giovannella. Recent results on radiative Kaon decays from NA48 and NA48/2 / S.G. López. Cusps in K-->3 [Pie symbol] decays / B. Kubis. Recent KTeV results on radiative Kaon decays / M.C. Ronquest. The [Double pie symbols] scattering amplitude / J.R. Peláez. Determination of the Regge parameters in the [Double pie symbols] scattering amplitude / I. Caprini. e+e- Hadronic cross section measurement at DA[symbol]NE with the KLOE detector / P. Beltrame. Measurement of the form factors of e+e- -->2([Pie symbol]+[Pie symbol]-), pp and the resonant parameters of the heavy charmonia at BES / H. Hu. Measurement of e+e- multihadronic cross section below 4

  9. Synthesis of Novel Chiral Stationary Phase Based on Atom Transfer Radical Polymerization and Click Chemistry%基于原子转移自由基聚合和“Click”化学方法制备手性色谱固定相

    Institute of Scientific and Technical Information of China (English)

    王怀松; 彭江涛; 魏纪平; 姜安

    2012-01-01

    应用原子转移自由基聚合(ATRP)法和“Click”化学方法,以含叠氮基的烯类化合物为单体,在硅胶表面引发聚合,制备了“梳状”手性固定相.该固定相的合成采用“接出”方法接枝聚合物链,使接枝层更为均匀,并且避免了传统合成方法(如物理吸附等)稳定性差的缺点.所得到的“梳状”手性固定相实现了对一些手性药物的分离;并考察了该固定相中聚合物链的密度和长度对其手性分离能力的影响.%A novel chiral stationary phase was synthesized via the combination of atom transfer radical po- lymerization (ATRP) and click chemistry. In the synthesis, the silane coupling agent 3-(2-bromoisobutyryl)- propyl triethoxysilane (BPE) was chosen as the ATRP initiator and immobized on the porous silica gel. The polymer chains of poly(2-methyl-3-butyn-2-ol methacrylate) (pMBMA) were grafted on the silica substrates by surface-initiated ATRP. This "grafting-from" technique was used to synthesize polymers with controlla- ble molecular weight and narrow molecular weight distributions. For immobilizing the chiral selector, azide-modified β-cyclodextrin (β-CD) was synthesized and bounded on the pMBMA by click chemistry, which can avoid the side-reactions in the preparation. The materials with different pMBMA chain density and length on the silica gel surface were prepared. Several pharmaceuticals were used to evaluate the enantioseparation ability of the materials under reversed-phase high performance liquid chromatography. The results demonstrate that ATRP can well design the polymer structure, and click chemistry can provide an ef- fective route in the β-CD immobilization for chiral discrimination. It was found that the retention and separation factors of chiral compounds could be improved by adjusting the pMBMA chain density and length on the surface of silica gel.

  10. On one-chiral-sector-dominated turbulence states

    CERN Document Server

    Zhu, Jian-Zhou

    2013-01-01

    Left- and right-handed chiral sectors of a hydrodynamic-type system present with helical decomposition. One-chiral-sector-dominated,i.e., nearly maximally helical ("force free" in the magnetic case), turbulence states are systematically examined with helically decomposed absolute equilibria of pure magnetodynamics (PMD, or electron magnetohydrodynamics - EMHD), pure hydrodynamics (PHD), and, single-fluid and two-fluid MHDs. In any case, real poles of the absolute equilibrium spectra of the two chiral sectors are of opposite signs, so one sector dominates near its pole. Nearly force-free state at large scales is generically supported by the absolute equilibria of the models involving magnetic fields. We revisit some documented data and relevant issues, such as cascade properties, and, helical and nonhelical dynamo etc.. We also discuss new scenarios, such as the inverse magnetic helicity and forward energy dual transfers (may be cascades) in PMD (or EMHD), and, the continuous transition from completely-inverse...

  11. Chiral resolution of spin angular momentum in linearly polarized and unpolarized light.

    Science.gov (United States)

    Hernández, R J; Mazzulla, A; Provenzano, C; Pagliusi, P; Cipparrone, G

    2015-11-20

    Linearly polarized (LP) and unpolarized (UP) light are racemic entities since they can be described as superposition of opposite circularly polarized (CP) components of equal amplitude. As a consequence they do not carry spin angular momentum. Chiral resolution of a racemate, i.e. separation of their chiral components, is usually performed via asymmetric interaction with a chiral entity. In this paper we provide an experimental evidence of the chiral resolution of linearly polarized and unpolarized Gaussian beams through the transfer of spin angular momentum to chiral microparticles. Due to the interplay between linear and angular momentum exchange, basic manipulation tasks, as trapping, spinning or orbiting of micro-objects, can be performed by light with zero helicity. The results might broaden the perspectives for development of miniaturized and cost-effective devices.

  12. Chirality of 4,4'-Biphenylene Bridged Polybissilsesquioxane Nanotubes Using the Dipeptides Derived from Valine.

    Science.gov (United States)

    Sang, Yunsen; Guo, Yongmin; Wang, Hairui; Li, Yi; Li, Baozong; Yang, Yonggang

    2015-03-01

    Four dipeptides with alkyl chains derived from L- and D-valines were synthesized, the handedness of their self-assemblies were controlled by the valine chirality at the terminals. The stacking of the carbonyl groups plays an important in the formation of chiral organic self-assemblies. Chiral 4,4'-biphenylene bridged polybissilsesquioxane nanotubes were prepared using the self-assemblies of these dipeptides as the templates. The chirality of the polysilsesquioxane nanotubes was mainly controlled by the valines at the terminals of the dipeptides, which was transferred from the valines at the terminals through electrostatic interaction. The valines near the alkyl chains could also affect the polysilsesquioxane chirality through hydrogen bonding.

  13. Dileptons and Chiral Symmetry Restoration

    CERN Document Server

    Hohler, P M

    2015-01-01

    We report on recent work relating the medium effects observed in dilepton spectra in heavy-ion collisions to potential signals of chiral symmetry restoration. The key connection remains the approach to spectral function degeneracy between the vector-isovector channel with its chiral partner, the axialvector-isovector channel. Several approaches are discussed to elaborate this connection, namely QCD and Weinberg sum rules with input for chiral order parameters from lattice QCD, and chiral hadronic theory to directly evaluate the medium effects of the axialvector channel and the pertinent pion decay constant as function of temperature. A pattern emerges where the chiral mass splitting between rho and a_1 burns off and is accompanied by a strong broadening of the spectral distributions.

  14. Applications Of Chiral Perturbation Theory

    CERN Document Server

    Mohta, V

    2005-01-01

    Effective field theory techniques are used to describe the spectrum and interactions of hadrons. The mathematics of classical field theory and perturbative quantum field theory are reviewed. The physics of effective field theory and, in particular, of chiral perturbation theory and heavy baryon chiral perturbation theory are also reviewed. The geometry underlying heavy baryon chiral perturbation theory is described in detail. Results by Coleman et. al. in the physics literature are stated precisely and proven. A chiral perturbation theory is developed for a multiplet containing the recently- observed exotic baryons. A small coupling expansion is identified that allows the calculation of self-energy corrections to the exotic baryon masses. Opportunities in lattice calculations are discussed. Chiral perturbation theory is used to study the possibility of two multiplets of exotic baryons mixed by quark masses. A new symmetry constraint on reduced partial widths is identified. Predictions in the literature based ...

  15. Quark structure of chiral solitons

    CERN Document Server

    Diakonov, D

    2004-01-01

    There is a prejudice that the chiral soliton model of baryons is something orthogonal to the good old constituent quark models. In fact, it is the opposite: the spontaneous chiral symmetry breaking in strong interactions explains the appearance of massive constituent quarks of small size thus justifying the constituent quark models, in the first place. Chiral symmetry ensures that constituent quarks interact very strongly with the pseudoscalar fields. The ``chiral soliton'' is another word for the chiral field binding constituent quarks. We show how the old SU(6) quark wave functions follow from the ``soliton'', however, with computable relativistic corrections and additional quark-antiquark pairs. We also find the 5-quark wave function of the exotic baryon Theta+.

  16. Observing Disoriented Chiral Condensates

    CERN Document Server

    Bjorken, James D; Taylor, C C

    1993-01-01

    We speculate that, in very high energy hadronic collisions, large fireballs may be produced with interiors which have anomalous chiral order parameters. Such a process would result in radiation of pions with distinctive momentum and isospin distributions, and may provide an explanation of Centauro and related phenomena in cosmic-ray events. The phenomenology of such events is reviewed, with emphasis on the possibility of observing such phenomena at Fermilab experiment T-864 (MiniMax), or at a Full Acceptance Detector (FAD) at the SSC.

  17. Chiral Nuclear Dynamics II

    CERN Document Server

    Rho, Mannque

    2008-01-01

    This is the sequel to the first volume to treat in one effective field theory framework the physics of strongly interacting matter under extreme conditions. This is vital for understanding the high temperature phenomena taking place in relativistic heavy ion collisions and in the early Universe, as well as the high-density matter predicted to be present in compact stars. The underlying thesis is that what governs hadronic properties in a heat bath and/or a dense medium is hidden local symmetry which emerges from chiral dynamics of light quark systems and from the duality between QCD in 4D and

  18. Spontaneous Chiral Symmetry Breaking as Condensation of Dynamical Chirality

    CERN Document Server

    Alexandru, Andrei

    2012-01-01

    The occurrence of spontaneous chiral symmetry breaking (SChSB) is equivalent to sufficient abundance of Dirac near-zeromodes. However, dynamical mechanism leading to breakdown of chiral symmetry should be naturally reflected in chiral properties of the modes. Here we offer such connection, presenting evidence that SChSB in QCD proceeds via the appearance of modes exhibiting dynamical tendency for local chiral polarization. These modes form a band of finite width Lambda_ch (chiral polarization scale) around the surface of otherwise anti--polarized Dirac sea, and condense. Lambda_ch characterizes the dynamics of the breaking phenomenon and can be converted to a quark mass scale, thus offering conceptual means to determine which quarks of nature are governed by broken chiral dynamics. It is proposed that, within the context of SU(3) gauge theories with fundamental Dirac quarks, mode condensation is equivalent to chiral polarization, making Lambda_ch an "order parameter" of SChSB. Several uses of these features, ...

  19. Repulsive Casimir Force in Chiral Metamaterials

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, R.; Zhou, J.; Koschny, Th.; Economou, E.N.; Soukoulis, C.M.

    2009-09-04

    We demonstrate theoretically that one can obtain repulsive Casimir forces and stable nanolevitations by using chiral metamaterials. By extending the Lifshitz theory to treat chiral metamaterials, we find that a repulsive force and a minimum of the interaction energy possibly exist for strong chirality, under realistic frequency dependencies and correct limiting values (for zero and infinite frequencies) of the permittivity, permeability, and chiral coefficients.

  20. Repulsive Casimir Force in Chiral Metamaterials

    OpenAIRE

    Zhao, R.; J. Zhou; Koschny, Th.; Economou, E. N.; C M Soukoulis

    2009-01-01

    We demonstrate theoretically that one can obtain repulsive Casimir forces and stable nanolevitations by using chiral metamaterials. By extending the Lifshitz theory to treat chiral metamaterials, we find that a repulsive force and a minimum of the interaction energy exist for strong chirality, under realistic frequency dependencies and correct limiting values (for zero and infinite frequencies) of the permittivity, permeability, and chiral coefficients.

  1. Repulsive Casimir Force in Chiral Metamaterials

    Science.gov (United States)

    Zhao, R.; Zhou, J.; Koschny, Th.; Economou, E. N.; Soukoulis, C. M.

    2009-09-01

    We demonstrate theoretically that one can obtain repulsive Casimir forces and stable nanolevitations by using chiral metamaterials. By extending the Lifshitz theory to treat chiral metamaterials, we find that a repulsive force and a minimum of the interaction energy possibly exist for strong chirality, under realistic frequency dependencies and correct limiting values (for zero and infinite frequencies) of the permittivity, permeability, and chiral coefficients.

  2. Nanoscale chirality in metal and semiconductor nanoparticles.

    Science.gov (United States)

    Kumar, Jatish; Thomas, K George; Liz-Marzán, Luis M

    2016-10-18

    The field of chirality has recently seen a rejuvenation due to the observation of chirality in inorganic nanomaterials. The advancements in understanding the origin of nanoscale chirality and the potential applications of chiroptical nanomaterials in the areas of optics, catalysis and biosensing, among others, have opened up new avenues toward new concepts and design of novel materials. In this article, we review the concept of nanoscale chirality in metal nanoclusters and semiconductor quantum dots, then focus on recent experimental and theoretical advances in chiral metal nanoparticles and plasmonic chirality. Selected examples of potential applications and an outlook on the research on chiral nanomaterials are additionally provided.

  3. Nonequilibrium chiral perturbation theory and disoriented chiral condensates

    CERN Document Server

    Nicola, A G

    1999-01-01

    We analyse the extension of Chiral Perturbation Theory to describe a meson gas out of thermal equilibrium. For that purpose, we let the pion decay constant be a time-dependent function and work within the Schwinger-Keldysh contour technique. A useful connection with curved space-time QFT allows to consistently renormalise the model, introducing two new low-energy constants in the chiral limit. We discuss the applicability of our approach within a Relativistic Heavy-Ion Collision environment. In particular, we investigate the formation of Disoriented Chiral Condensate domains in this model, via the parametric resonance mechanism.

  4. Chiral quantum optics.

    Science.gov (United States)

    Lodahl, Peter; Mahmoodian, Sahand; Stobbe, Søren; Rauschenbeutel, Arno; Schneeweiss, Philipp; Volz, Jürgen; Pichler, Hannes; Zoller, Peter

    2017-01-25

    Advanced photonic nanostructures are currently revolutionizing the optics and photonics that underpin applications ranging from light technology to quantum-information processing. The strong light confinement in these structures can lock the local polarization of the light to its propagation direction, leading to propagation-direction-dependent emission, scattering and absorption of photons by quantum emitters. The possibility of such a propagation-direction-dependent, or chiral, light-matter interaction is not accounted for in standard quantum optics and its recent discovery brought about the research field of chiral quantum optics. The latter offers fundamentally new functionalities and applications: it enables the assembly of non-reciprocal single-photon devices that can be operated in a quantum superposition of two or more of their operational states and the realization of deterministic spin-photon interfaces. Moreover, engineered directional photonic reservoirs could lead to the development of complex quantum networks that, for example, could simulate novel classes of quantum many-body systems.

  5. Chiral imbalance in QCD

    Directory of Open Access Journals (Sweden)

    Andrianov Alexander

    2017-01-01

    Full Text Available The chiral imbalance (ChI is given by a difference between the numbers of RH and LH quarks which may occur in the fireball after heavy ion collision. To characterize it adiabatically a quark chiral (axial chemical potential must be introduced taking into account emergence of a ChI in such a phase. In this report the phenomenology of formation of Local spatial Parity Breaking (LPB in the hot and dense baryon matter is discussed and its simulation within a number of QCD-inspired models is outlined. The appearance of new states in the spectra of scalar, pseudoscalar and vector particles in such a matter is elucidated. In particular, from the effective vector meson theory in the presence of Chern-Simons interaction it is demonstrated that the spectrum of massive vector mesons splits into three polarization components with different effective masses. The asymmetry in production of longitudinally and transversely polarized states of ρ and ω mesons for various values of the dilepton invariant mass can serve as a characteristic indication of the LPB in PHENIX, STAR and ALICE experiments.

  6. Chirally extended quantum chromodynamics

    CERN Document Server

    Brower, R C; Tan, C I; Richard C Brower; Yue Shen; Chung-I Tan

    1994-01-01

    We propose an extended Quantum Chromodynamics (XQCD) Lagrangian in which the fermions are coupled to elementary scalar %\\sigma and \\pi fields through a Yukawa coupling which preserves chiral invariance. Our principle motivation is to find a new lattice formulation for QCD which avoids the source of critical slowing down usually encountered as the bare quark mass is tuned to the chiral limit. The phase diagram and the weak coupling limit for XQCD are studied. They suggest a conjecture that the continuum limit of XQCD is the same as the continuum limit of conventional lattice formulation of QCD. As examples of such universality, we present the large N solutions of two prototype models for XQCD, in which the mass of the spurious pion and sigma resonance go to infinity with the cut-off. Even if the universality conjecture turns out to be false, we believe that XQCD will still be useful as a low energy effective action for QCD phenomenology on the lattice. Numerical simulations are recommended to further investiga...

  7. Dynamic Figure Eight Chirality: Multifarious Inversions of a Helical Preference Induced by Complexation.

    Science.gov (United States)

    Katoono, Ryo; Tanaka, Yuki; Kusaka, Keiichi; Fujiwara, Kenshu; Suzuki, Takanori

    2015-08-07

    We demonstrate two types of inversion of a helical preference upon the 1:1 complexation of a dynamic figure eight molecule with a guest molecule through the controlled transmission of point chirality. We designed a series of macrocycles that prefer a nonplanar conformation with figure eight chirality. These macrocycles are composed of a chirality-transferring unit (terephthalamide) and a structure-modifying unit (two o-phenylene rings spaced with a varying number of triple bonds). The former unit provides a binding site for capturing a guest molecule through the formation of hydrogen bonds. The attachment of chiral auxiliaries to the former unit induces a helical preference for a particular sense through the intramolecular transmission of point chirality. For relatively small-sized macrocycles, the preferred sense was reversed upon complexation with an achiral guest. Contrary preferences before and after complexation were both seen for chiral auxiliaries associated with a figure eight host through two-way intramolecular transmission of the single chiral source. Alternatively, the helical preference induced in relatively large-sized macrocycles was reversed only when a figure eight host formed a 1:1 complex with a particular enantiomeric guest through the supramolecular transmission of point chirality in the guest. This stereospecific inversion of a helical preference is rare.

  8. Chiral quantum dot based materials

    Science.gov (United States)

    Govan, Joseph; Loudon, Alexander; Baranov, Alexander V.; Fedorov, Anatoly V.; Gun'ko, Yurii

    2014-05-01

    Recently, the use of stereospecific chiral stabilising molecules has also opened another avenue of interest in the area of quantum dot (QD) research. The main goal of our research is to develop new types of technologically important quantum dot materials containing chiral defects, study their properties and explore their applications. The utilisation of chiral penicillamine stabilisers allowed the preparation of new water soluble white emitting CdS quantum nanostructures which demonstrated circular dichroism in the band-edge region of the spectrum. It was also demonstrated that all three types of QDs (D-, L-, and Rac penicillamine stabilised) show very broad emission bands between 400 and 700 nm due to defects or trap states on the surfaces of the nanocrystals. In this work the chiral CdS based quantum nanostructures have also been doped by copper metal ions and new chiral penicilamine stabilized CuS nanoparticles have been prepared and investigated. It was found that copper doping had a strong effect at low levels in the synthesis of chiral CdS nanostructures. We expect that this research will open new horizons in the chemistry of chiral nanomaterials and their application in biotechnology, sensing and asymmetric synthesis.

  9. Coupling chiral bosons to gravity

    CERN Document Server

    Braga, N R F; Braga, N R F; Wotzasek, C

    1995-01-01

    chiral boson actions of Floreanini and Jackiw (FJ), and of McClain,Wu and Yu (MWY) have been recently shown to be different representations of the same chiral boson theory. MWY displays manifest covariance and also a (gauge) symmetry that is hidden in the FJ side, which, on the other hand, displays the physical spectrum in a simple manner. We make use of the covariance of the MWY representation for the chiral boson to couple it to background gravity showing explicitly the equivalence with the previous results for the FJ representation

  10. Chiral gravity in higher dimensions

    CERN Document Server

    Ootsuka, T; Ura, K; Ootsuka, Takayoshi; Tanaka, Erico; Ura, Kousuke

    2003-01-01

    We construct a chiral theory of gravity in 7 and 8 dimensions, which are equivalent to Einstein-Cartan theory using less variables. In these dimensions, we can construct such higher dimensional chiral gravity because of the existence of gravitational instanton. The octonionic-valued variables in the theory represent the deviation from the gravitational instanton, and from their non-associativity, prevents the theory to be SO(n) gauge invariant. Still the chiral gravity holds G_2 (7-D), and Spin(7) (8-D) gauge symmetry.

  11. Chiral Fermions on the Lattice

    CERN Document Server

    Bietenholz, Wolfgang

    2010-01-01

    In the last century the non-perturbative regularization of chiral fermions was a long-standing problem. We review how this problem was finally overcome by the formulation of a modified but exact form of chiral symmetry on the lattice. This also provides a sound definition of the topological charge of lattice gauge configurations. We illustrate a variety of applications to QCD in the p-, the epsilon- and the delta-regime, where simulation results can now be related to Random Matrix Theory and Chiral Perturbation Theory. The latter contains Low Energy Constants as free parameters, and we comment on their evaluation from first principles of QCD.

  12. POLYMERIZATION MECHANISM OF N-VINYLCARBAZOLE WITH CHIRALLY ORGANIC SALT AS CATALYST

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    The polymerization mechanism is described by the conductance change with the time during the polymerization. The mechanism can be explained by the equilibrium feature (i.e. main ion-pairs) between the free ions and the ion-pairs dissociated by the organic salt (-) Sp*+ (+) CSA*- (An asterisk represents the chirality) and the scheme of the polymerization process isdescribed mainly by the charge transfer complexes having chiral induction power.

  13. Field induced spin chirality and chirality switching in magnetic multilayers

    Energy Technology Data Exchange (ETDEWEB)

    Tartakovskaya, Elena V., E-mail: elena_tartakovskaya@yahoo.com [Institute of Magnetism NAS of Ukraine, Vernadsky blvd 36b, 03142 Kiev (Ukraine); Institute of High Technologies, Taras Shevchenko National University of Kiev, 03022 Kiev (Ukraine)

    2015-05-01

    The physical origin of the field-induced spin chirality experimentally observed in rare earth multilayers is determined. It is shown that the effect is possible due to the interplay between solid-state exchange interactions (the Ruderman–Kittel–Kasuya–Yosida and the Dsyaloshinsky–Moriya interactions), the external magnetic field and a special confinement of magnetic constituents. The presented model describes a certain temperature dependence of the chirality factor in agreement with experimental data and opens a new way to design nanostructured objects with predicted handedness. - Highlights: • Field-induced spin chirality in magnetic multilayers is explained. • The roles of the RKKY, the DM and the Zeeman interactions are clarified. • Theoretical analysis of the chirality factor is in agreement with experimental data.

  14. Chiral Relaxation Time at the Chiral Crossover of Quantum Chromodynamics

    CERN Document Server

    Ruggieri, M; Chernodub, M

    2016-01-01

    We study microscopic processes responsible for chirality flips in the thermal bath of Quantum Chromodynamics at finite temperature and zero baryon chemical potential. We focus on the temperature range where the crossover from chirally broken phase to quark-gluon plasma takes place, namely $T \\simeq (150, 200)$ MeV. The processes we consider are quark-quark scatterings mediated by collective excitations with the quantum number of pions and $\\sigma$-meson, hence we refer to these processes simply as \\sugg{to} one-pion (one-$\\sigma$) exchange\\sugg{s}. We use a Nambu-Jona-Lasinio model to compute equilibrium properties of the thermal bath, as well as the relevant scattering kernel to be used in the collision integral to estimate the chiral relaxation time $\\tau$. We find $\\tau\\simeq 0.1 \\div 1$ fm/c around the chiral crossover.

  15. Consistent chiral kinetic theory in Weyl materials: chiral magnetic plasmons

    CERN Document Server

    Gorbar, E V; Shovkovy, I A; Sukhachov, P O

    2016-01-01

    We argue that the correct definition of the electric current in the chiral kinetic theory for Weyl materials should include the Chern--Simons contribution that makes the theory consistent with the local conservation of the electric charge in electromagnetic and strain-induced pseudoelectromagnetic fields. By making use of such a kinetic theory, we study the plasma frequencies of collective modes in Weyl materials in constant magnetic and pseudomagnetic fields taking into account the effects of dynamical electromagnetism. We show that the collective modes are chiral plasmons. While the plasma frequency of the longitudinal collective mode coincides with the Langmuir one, this mode is unusual because it is characterized not only by oscillations of the electric current density, but also oscillations of the chiral current density. The latter are triggered by a dynamical version of the chiral electric separation effect. We also find that the plasma frequencies of the transverse modes split up in a magnetic field. T...

  16. Chirality in photonic systems

    Science.gov (United States)

    Solnyshkov, Dmitry; Malpuech, Guillaume

    2016-10-01

    The optical modes of photonic structures are the so-called TE and TM modes that bring intrinsic spin-orbit coupling and chirality to these systems. This, combined with the unique flexibility of design of the photonic potential, and the possibility to mix photon states with excitonic resonances, sensitive to magnetic field and interactions, allows us to achieve many phenomena, often analogous to other solid-state systems. In this contribution, we review in a qualitative and comprehensive way several of these realizations, namely the optical spin Hall effect, the creation of spin currents protected by a non-trivial geometry, the Berry curvature for photons, and the photonic/polaritonic topological insulator.

  17. Reducible chiral metamaterials

    CERN Document Server

    Ciattoni, Alessandro; Rizza, Carlo

    2016-01-01

    We introduce the concept of 3D reducible metamaterials whose constituent permittivity can be modelled by a factorized profile. The separated cartesian coordinates dependence, easily achieved in all-optical reconfigurable materials, allows to physically regard a reducible metamaterial as a superposition of three fictitious 1D generating media. We prove that, in the long-wavelength limit, the electromagnetic response of reducible metamaterials can be reconstructed from the properties of the 1D generating media whose interplay provides large freedom to control the electromagnetic chirality. Our approach introduces an unprecedented decomposition strategy in metamaterial science which allows the full ab-initio and flexible design of a complex 3D bianisotropic response by using 1D metamaterials as basic building blocks.

  18. Amino Acids and Chirality

    Science.gov (United States)

    Cook, Jamie E.

    2012-01-01

    Amino acids are among the most heavily studied organic compound class in carbonaceous chondrites. The abundance, distributions, enantiomeric compositions, and stable isotopic ratios of amino acids have been determined in carbonaceous chondrites fi'om a range of classes and petrographic types, with interesting correlations observed between these properties and the class and typc of the chondritcs. In particular, isomeric distributions appear to correlate with parent bodies (chondrite class). In addition, certain chiral amino acids are found in enantiomeric excess in some chondrites. The delivery of these enantiomeric excesses to the early Earth may have contributed to the origin of the homochirality that is central to life on Earth today. This talk will explore the amino acids in carbonaceous chondritcs and their relevance to the origin of life.

  19. Domains of Disoriented Chiral Condensate

    CERN Document Server

    Amado, R D; Lu, Yang

    1996-01-01

    The probability distribution of neutral pion fraction from independent domains of disoriented chiral condensate is characterized. The signal for the condensate is clear for a small number of domains but is greatly reduced for more than three.

  20. Review of chiral perturbation theory

    Indian Academy of Sciences (India)

    B Ananthanarayan

    2003-11-01

    A review of chiral perturbation theory and recent developments on the comparison of its predictions with experiment is presented. Some interesting topics with scope for further elaboration are touched upon.

  1. Chiral Dynamics With Wilson Fermions

    CERN Document Server

    Splittorff, K

    2012-01-01

    Close to the continuum the lattice spacing affects the smallest eigenvalues of the Wilson Dirac operator in a very specific manner determined by the way in which the discretization breaks chiral symmetry. These effects can be computed analytically by means of Wilson chiral perturbation theory and Wilson random matrix theory. A number of insights on chiral Dynamics with Wilson fermions can be obtained from the computation of the microscopic spectrum of the Wilson Dirac operator. For example, the unusual volume scaling of the smallest eigenvalues observed in lattice simulations has a natural explanation. The dynamics of the eigenvalues of the Wilson Dirac operator also allow us to determine the additional low energy constants of Wilson chiral perturbation theory and to understand why the Sharpe-Singleton scenario is only realized in unquenched simulations.

  2. Chirally motivated K - nuclear potentials

    Science.gov (United States)

    Cieplý, A.; Friedman, E.; Gal, A.; Gazda, D.; Mareš, J.

    2011-08-01

    In-medium subthreshold Kbar N scattering amplitudes calculated within a chirally motivated meson-baryon coupled-channel model are used self consistently to confront K- atom data across the periodic table. Substantially deeper K- nuclear potentials are obtained compared to the shallow potentials derived in some approaches from threshold Kbar N amplitudes, with Re VK-chiral = - (85 ± 5) MeV at nuclear matter density. When Kbar NN contributions are incorporated phenomenologically, a very deep K- nuclear potential results, Re VK-chiral + phen . = - (180 ± 5) MeV, in agreement with density dependent potentials obtained in purely phenomenological fits to the data. Self consistent dynamical calculations of K--nuclear quasibound states generated by VK-chiral are reported and discussed.

  3. Chiral Quark Model of Mesons

    CERN Document Server

    Wang, X J; Wang, Xiao-Jun; Yan, Mu-Lin

    1999-01-01

    We study SU(3)$_L\\timesSU(3)_R$ chiral quark model of mesons up to next leading order of $1/N_c$ expansion. Composite vector and axial-vector mesons resonances are introduced via non-linear realization of chiral SU(3) and vector meson dominant. Effects of one-loop graphs of pseudoscalar, vector and axial-vector mesons is calculated systematically and the significant results are obtained. Correction of effective gluon interaction is studied too. The light quark masses are introduced via new mechanism which agree with phenomenology and the requirement of chiral symmetry. Up to powers four of derivatives, chiral effective lagrangian of mesons is derived and evaluated to next leading order of $1/N_c$. Low energy limit of the model is examined. Ten low energy coupling constants $L_i(i=1,2,...,10)$ in ChPT are obtained and agree with ChPT well.

  4. Homogenization of resonant chiral metamaterials

    DEFF Research Database (Denmark)

    Andryieuski, Andrei; Menzel, C.; Rockstuhl, Carsten

    2010-01-01

    Homogenization of metamaterials is a crucial issue as it allows to describe their optical response in terms of effective wave parameters as, e.g., propagation constants. In this paper we consider the possible homogenization of chiral metamaterials. We show that for meta-atoms of a certain size...... an analytical criterion for performing the homogenization and a tool to predict the homogenization limit. We show that strong coupling between meta-atoms of chiral metamaterials may prevent their homogenization at all....

  5. Chiral thermodynamics of nuclear matter

    Energy Technology Data Exchange (ETDEWEB)

    Fiorilla, Salvatore

    2012-10-23

    The equation of state of nuclear matter is calculated at finite temperature in the framework of in-medium chiral perturbation theory up to three-loop order. The dependence of its thermodynamic properties on the isospin-asymmetry is investigated. The chiral quark condensate is evaluated for symmetric nuclear matter. Its behaviour as a function of density and temperature sets important nuclear physics constraints for the QCD phase diagram.

  6. Baryon spectrum and chiral dynamics

    CERN Document Server

    Glozman, L Ya

    1995-01-01

    New results on baryon structure and spectrum developed in collaboration with Dan Riska [1-4] are reported. The main idea is that beyond the chiral symmetry spontaneous breaking scale light and strange baryons should be considered as systems of three constituent quarks with an effective confining interaction and a chiral interaction that is mediated by the octet of Goldstone bosons (pseudoscalar mesons) between the constituent quarks.

  7. Bottom-up synthesis of chiral covalent organic frameworks and their bound capillaries for chiral separation.

    Science.gov (United States)

    Qian, Hai-Long; Yang, Cheng-Xiong; Yan, Xiu-Ping

    2016-07-12

    Covalent organic frameworks (COFs) are a novel class of porous materials, and offer great potential for various applications. However, the applications of COFs in chiral separation and chiral catalysis are largely underexplored due to the very limited chiral COFs available and their challenging synthesis. Here we show a bottom-up strategy to construct chiral COFs and an in situ growth approach to fabricate chiral COF-bound capillary columns for chiral gas chromatography. We incorporate the chiral centres into one of the organic ligands for the synthesis of the chiral COFs. We subsequently in situ prepare the COF-bound capillary columns. The prepared chiral COFs and their bound capillary columns give high resolution for the separation of enantiomers with excellent repeatability and reproducibility. The proposed strategy provides a promising platform for the synthesis of chiral COFs and their chiral separation application.

  8. Bottom-up synthesis of chiral covalent organic frameworks and their bound capillaries for chiral separation

    Science.gov (United States)

    Qian, Hai-Long; Yang, Cheng-Xiong; Yan, Xiu-Ping

    2016-07-01

    Covalent organic frameworks (COFs) are a novel class of porous materials, and offer great potential for various applications. However, the applications of COFs in chiral separation and chiral catalysis are largely underexplored due to the very limited chiral COFs available and their challenging synthesis. Here we show a bottom-up strategy to construct chiral COFs and an in situ growth approach to fabricate chiral COF-bound capillary columns for chiral gas chromatography. We incorporate the chiral centres into one of the organic ligands for the synthesis of the chiral COFs. We subsequently in situ prepare the COF-bound capillary columns. The prepared chiral COFs and their bound capillary columns give high resolution for the separation of enantiomers with excellent repeatability and reproducibility. The proposed strategy provides a promising platform for the synthesis of chiral COFs and their chiral separation application.

  9. Observations of Chiral Odd GPDs and Their Implications

    Science.gov (United States)

    Goldstein, Gary R.; Liuti, Simonetta; Gonzalez-Hernandez, J. Osvaldo

    2014-01-01

    Our original suggestion to investigate exclusive π0 electroproduction as a method for extracting the tensor charge, transversity, and other quantities related to chiral odd generalized parton distributions from cross section and asymmetry data is reviewed. We explain some of the details of the process: i) the connection between the helicity description and the cartesian basis; ii) the dependence on the momentum transfer squared, Q2, and iii) the angular momentum, parity, and charge conjugation constraints (JPC quantum numbers).

  10. Chirality in Bare and Passivated Gold Nanoclusters

    CERN Document Server

    Garzon, I L; Rodrigues-Hernandez, J I; Sigal, I; Beltran, M R; Michaelian, K

    2002-01-01

    Chiral structures have been found as the lowest-energy isomers of bare (Au$_{28}$ and Au$_{55}) and thiol-passivated (Au$_{28}(SCH$_{3})$_{16}$ and Au$_{38}$(SCH$_{3}$)$_{24}) gold nanoclusters. The degree of chirality existing in the chiral clusters was calculated using the Hausdorff chirality measure. We found that the index of chirality is higher in the passivated clusters and decreases with the cluster size. These results are consistent with the observed chiroptical activity recently reported for glutahione-passivated gold nanoclusters, and provide theoretical support for the existence of chirality in these novel compounds.

  11. Using the Chiral Organophosphorus Derivatizing Agents for Determination of the Enantiomeric Composition of Chiral Carboxylic Acids by 31PNMR Spectroscopy

    Institute of Scientific and Technical Information of China (English)

    Chao CHE; Zhong Ning ZHANG; Gui Lan HUANG; Xin Xing WANG; Zhao Hai QIN

    2004-01-01

    The use of chiral organophosphorus derivatizing agents prepared in situ from chiral tartrate or chiral diamine for the 31PNMR determination of the enantiomeric composition of chiral carboxylic acids is described. The method is accurate, reliable and convenient.

  12. Consistent Chiral Kinetic Theory in Weyl Materials: Chiral Magnetic Plasmons

    Science.gov (United States)

    Gorbar, E. V.; Miransky, V. A.; Shovkovy, I. A.; Sukhachov, P. O.

    2017-03-01

    We argue that the correct definition of the electric current in the chiral kinetic theory for Weyl materials should include the Chern-Simons contribution that makes the theory consistent with the local conservation of the electric charge in electromagnetic and strain-induced pseudoelectromagnetic fields. By making use of such a kinetic theory, we study the plasma frequencies of collective modes in Weyl materials in constant magnetic and pseudomagnetic fields, taking into account the effects of dynamical electromagnetism. We show that the collective modes are chiral plasmons. While the plasma frequency of the longitudinal collective mode coincides with the Langmuir one, this mode is unusual because it is characterized not only by oscillations of the electric current density, but also by oscillations of the chiral current density. The latter are triggered by a dynamical version of the chiral electric separation effect. We also find that the plasma frequencies of the transverse modes split up in a magnetic field. This finding suggests an efficient means of extracting the chiral shift parameter from the measurement of the plasma frequencies in Weyl materials.

  13. Bulky melamine-based Zn-porphyrin tweezer as a CD probe of molecular chirality.

    Science.gov (United States)

    Petrovic, Ana G; Vantomme, Ghislaine; Negrón-Abril, Yashira L; Lubian, Elisa; Saielli, Giacomo; Menegazzo, Ileana; Cordero, Roselynn; Proni, Gloria; Nakanishi, Koji; Carofiglio, Tommaso; Berova, Nina

    2011-10-01

    The transfer of chirality from a guest molecule to an achiral host is the subject of significant interest especially when, upon chiral induction, the chiroptical response of the host/guest complex can effectively report the absolute configuration (AC) of the guest. For more than a decade, dimeric metalloporphyrin hosts (tweezers) have been successfully applied as chirality probes for determination of the AC for a wide variety of chiral synthetic compounds and natural products. The objective of this study is to investigate the utility of a new class of melamine-bridged Zn-porphyrin tweezers as sensitive AC reporters. A combined approach based on an experimental CD analysis and a theoretical prediction of the prevailing interporphyrin helicity demonstrates that these tweezers display favorable properties for chiral recognition. Herein, we discuss the application of the melamine-bridged tweezer to the chiral recognition of a diverse set of chiral guests, such as 1,2-diamines, α-amino-esters and amides, secondary alcohols, and 1,2-amino-alcohols. The bulky periphery and the presence of a rigid porphyrin linkage lead, in some cases, to a more enhanced CD sensitivity than that reported earlier with other tweezers.

  14. Can a Non-Chiral Object Be Made of Two Identical Chiral Moieties?

    Science.gov (United States)

    LeMarechal, Jean Francois

    2008-01-01

    Several pedagogical objects can be used to discuss chirality. Here, we use the cut of an apple to show that the association of identical chiral moieties can form a non-chiral object. Octahedral chirality is used to find situations equivalent to the cut of the apple. (Contains 5 figures.)

  15. An Inherent Chiral Calix[4]arene Bearing Chiral Groups without Forming Sub-ring

    Institute of Scientific and Technical Information of China (English)

    Xian Xian LIU; Yan Song ZHENG; Wan Ling MO

    2006-01-01

    The NMR spectra revealed that the calixarene frame of 1, 3-disubstituted calix[4]arenes bearing optically active groups is asymmetric, even without the formation of a sub-ring. This inherent chirality arises from the interaction of the two chiral groups, which hinder the substituents' free rotation. Thus, these chiral calix[4]arenes display good chiral recognition ability.

  16. Chaos of chiral condensate

    CERN Document Server

    Hashimoto, Koji; Yoshida, Kentaroh

    2016-01-01

    Assigning a chaos index for vacua of generic quantum field theories is a challenging problem. We find chaotic behavior of chiral condensates of a quantum gauge theory at strong coupling limit, by using the AdS/CFT correspondence. We evaluate the time evolution of homogeneous quark condensates and in an N=2 supersymmetric QCD with the SU(N_c) gauge group at large N_c and at large 't Hooft coupling lambda. At an equivalent classical gravity picture, a Lyapunov exponent is readily defined. We show that the condensates exhibit chaotic behavior for energy density E > (6x10^2) (N_c/lambda^2) (m_q)^4 where m_q is the quark mass. The energy region of the chaotic vacua of the N=2 supersymmetric QCD increases for smaller N_c or larger lambda. The Lyapunov exponent is calculated as a function of the theory (N_c,lambda,E), showing that the N=2 supersymmetric QCD is more chaotic for smaller N_c.

  17. Dynamical evolution of the chiral magnetic effect: applications to the quark-gluon plasma

    CERN Document Server

    Manuel, Cristina

    2015-01-01

    We study the dynamical evolution of the so-called chiral magnetic effect in an electromagnetic conductor. To this end, we consider the coupled set of corresponding Maxwell and chiral anomaly equations, and we prove that these can be derived from chiral kinetic theory. After integrating the chiral anomaly equation over space in a closed volume, it leads to a quantum conservation law of the total helicity of the system. A change in the magnetic helicity density comes together with a modification of the chiral fermion density. We study in Fourier space the coupled set of anomalous equations and we obtain the dynamical evolution of the magnetic fields, magnetic helicity density, and chiral fermion imbalance. Depending on the initial conditions we observe how the helicity might be transferred from the fermions to the magnetic fields, or vice versa, and find that the rate of this transfer also depends on the scale of wavelengths of the gauge fields in consideration. We then focus our attention on the quark-gluon pl...

  18. Chiral Thirring–Wess model

    Energy Technology Data Exchange (ETDEWEB)

    Rahaman, Anisur, E-mail: anisur.rahman@saha.ac.in

    2015-10-15

    The vector type of interaction of the Thirring–Wess model was replaced by the chiral type and a new model was presented which was termed as chiral Thirring–Wess model in Rahaman (2015). The model was studied there with a Faddeevian class of regularization. Few ambiguity parameters were allowed there with the apprehension that unitarity might be threatened like the chiral generation of the Schwinger model. In the present work it has been shown that no counter term containing the regularization ambiguity is needed for this model to be physically sensible. So the chiral Thirring–Wess model is studied here without the presence of any ambiguity parameter and it has been found that the model not only remains exactly solvable but also does not lose the unitarity like the chiral generation of the Schwinger model. The phase space structure and the theoretical spectrum of this new model have been determined in the present scenario. The theoretical spectrum is found to contain a massive boson with ambiguity free mass and a massless boson.

  19. Chiral Logs in Quenched QCD

    CERN Document Server

    Dong, S J; Horváth, I; Lee, F X; Liu, K F; Mathur, N; Zhang, J B

    2003-01-01

    The quenched chiral logs are examined on a $16^3 \\times 28$ lattice with Iwasaki gauge action and overlap fermions. The pion decay constant $f_{\\pi}$ is used to set the lattice spacing, $a = 0.200(3)$ fm. With pion mass as low as $\\sim 180 {\\rm MeV}$, we see the quenched chiral logs clearly in $m_{\\pi}^2/m$ and $f_P$, the pseudoscalar decay constant. We analyze the data to determine how low the pion mass needs to be in order for the quenched one-loop chiral perturbation theory ($\\chi$PT) to apply. With the constrained curve fitting, we are able to extract the quenched chiral log parameter $\\delta$ together with the chiral cutoff $\\Lambda_{\\chi}$ and other parameters. Only for $m_{\\pi} \\leq 300 {\\rm MeV}$ do we obtain a consistent and stable fit with a constant $\\delta$ which we determine to be 0.23(2). By comparing to the $12^3 \\times 28$ lattice, we estimate the finite volume effect to be about 1.8% for the smallest pion mass. We also study the quenched non-analytic terms in the nucleon and the $\\rho$ masses...

  20. Orientation-dependent handedness and chiral design

    OpenAIRE

    Efrati, Efi; Irvine, William T. M.

    2013-01-01

    Chirality occupies a central role in fields ranging from biological self-assembly to the design of optical metamaterials. The definition of chirality, as given by Lord Kelvin, associates chirality with the lack of mirror symmetry: the inability to superpose an object on its mirror image. While this definition has guided the classification of chiral objects for over a century, the quantification of handed phenomena based on this definition has proven elusive, if not impossible, as manifest in ...

  1. Chiral Decomposition For Non-Abelian Bosons

    CERN Document Server

    Braga, N R F; Braga, Nelson R. F.; Wotzasek, Clovis

    1996-01-01

    We study the non-abelian extension for the splitting of a scalar field into chiral components. Using this procedure we find a non ambiguous way of coupling a non abelian chiral scalar field to gravity. We start with a (non-chiral) WZW model covariantly coupled to a background metric and, after the splitting, arrive at two chiral Wess-Zumino-Witten (WZW) models coupled to gravity.

  2. Chiral gap effect in curved space

    CERN Document Server

    Flachi, Antonino

    2014-01-01

    We discuss a new type of QCD phenomenon induced in curved space. In the QCD vacuum a mass gap of Dirac fermions is attributed to the spontaneous breaking of chiral symmetry. If the curvature is positive large, the chiral condensate melts but a chiral invariant mass gap can still remain, which we name the chiral gap effect in curved space. This leads to decoupling of quark deconfinement which implies a view of black holes surrounded by a first-order QCD phase transition.

  3. Chirality: a relational geometric-physical property.

    Science.gov (United States)

    Gerlach, Hans

    2013-11-01

    The definition of the term chirality by Lord Kelvin in 1893 and 1904 is analyzed by taking crystallography at that time into account. This shows clearly that chirality is a relational geometric-physical property, i.e., two relations between isometric objects are possible: homochiral or heterochiral. In scientific articles the relational term chirality is often mistaken for the two valued measure for the individual (absolute) sense of chirality, an arbitrary attributive term.

  4. Bifurcated, modular syntheses of chiral annulet triazacyclononanes.

    Science.gov (United States)

    Argouarch, Gilles; Stones, Graham; Gibson, Colin L; Kennedy, Alan R; Sherrington, David C

    2003-12-21

    Three chiral 2,6-disubstituted tri-N-methyl azamacrocycles have been prepared by modular methods. These macrocycles were accessed from three chiral 1,4,7-triazaheptanes intermediates that were prepared by two independent routes. The first of these routes involved the benzylamine opening of chiral tosyl aziridines followed by debenzylation but was problematic on solubility grounds. A second, more effective, route was developed which avoided debenzylation by using ammonia in the nucleophilic opening of chiral tosyl aziridines.

  5. On the Biological Advantage of Chirality

    OpenAIRE

    1999-01-01

    The presence of chirality in the main molecules of life may well be not just a structural artifact, but of pure biological advantage. The possibility of the existence of a phenomenon of a special mode of interaction, labeled as "chiral interaction" (CI), for which structural chirality is a necessary condition, is the main reason for such an advantage. In order to demonstrate such a possibility, macroscopic chiral devices are introduced and presented as analogies for such an interaction. For t...

  6. Anomaly-driven inverse cascade and inhomogeneities in a magnetized chiral plasma in the early Universe

    CERN Document Server

    Gorbar, E V; Shovkovy, I A; Vilchinskii, S

    2016-01-01

    By making use of a simple model that captures the key features of the anomalous Maxwell equations, we study the role of inhomogeneities on the evolution of magnetic fields in a chiral plasma. We find that inhomogeneities of the chiral asymmetry by themselves do not prevent the anomaly-driven inverse cascade and, as in the homogeneous case, the magnetic helicity is transferred from shorter to longer wavelength helical modes of the magnetic field. However, we also find that the evolution appears to be sensitive to the effects of diffusion. In the case when diffusion is negligible, the inverse cascade slows down considerably compared to the homogeneous scenario. In the case of the primordial plasma, though, we find that the diffusion is substantial and efficiently suppresses chiral asymmetry inhomogeneities. As a result, the inverse cascade proceeds practically in the same way as in the chirally homogeneous model.

  7. Field induced spin chirality and chirality switching in magnetic multilayers

    Science.gov (United States)

    Tartakovskaya, Elena V.

    2015-05-01

    The physical origin of the field-induced spin chirality experimentally observed in rare earth multilayers is determined. It is shown that the effect is possible due to the interplay between solid-state exchange interactions (the Ruderman-Kittel-Kasuya-Yosida and the Dsyaloshinsky-Moriya interactions), the external magnetic field and a special confinement of magnetic constituents. The presented model describes a certain temperature dependence of the chirality factor in agreement with experimental data and opens a new way to design nanostructured objects with predicted handedness.

  8. Neutrino Oscillation Induced by Chiral Phase Transition

    Institute of Scientific and Technical Information of China (English)

    MU Cheng-Fu; SUN Gao-Feng; ZHUANG Peng-Fei

    2009-01-01

    Electric charge neutrality provides a relationship between chiral dynamics and neutrino propagation in compact stars.Due to the sudden drop of the electron density at the first-order chiral phase transition,the oscillation for low energy neutrinos is significant and can be regarded as a signature of chiral symmetry restoration in the core of compact stars.

  9. Quenched Chiral Perturbation Theory to one loop

    NARCIS (Netherlands)

    Colangelo, G.; Pallante, E.

    1998-01-01

    The divergences of the generating functional of quenched Chiral Perturbation theory (qCHPT) to one loop are computed in closed form. We show how the quenched chiral logarithms can be reabsorbed in the renormalization of the B0 parameter of the leading order Lagrangian. Finally, we do the chiral powe

  10. Shear Viscosity of Turbulent Chiral Plasma

    CERN Document Server

    Kumar, Avdhesh; Das, Amita; Kaw, P K

    2016-01-01

    It is well known that the difference between the chemical potentials of left-handed and right-handed particles in a parity violating (chiral) plasma can lead to an instability. We show that the chiral instability may drive turbulent transport. Further we estimate the anomalous viscosity of chiral plasma arising from the enhanced collisionality due to turbulence.

  11. Exact Chiral Symmetry on the Lattice

    CERN Document Server

    Neuberger, H

    2001-01-01

    Developments during the last eight years have refuted the folklore that chiral symmetries cannot be preserved on the lattice. The mechanism that permits chiral symmetry to coexist with the lattice is quite general and may work in Nature as well. The reconciliation between chiral symmetry and the lattice is likely to revolutionize the field of numerical QCD.

  12. Chiral cardiovascular drugs: an overview.

    Science.gov (United States)

    Ranade, Vasant V; Somberg, John C

    2005-01-01

    Stereochemistry in drug molecules is rapidly becoming an important aspect in drug research, design, and development. Recently, individual stereoisomers of drug molecules with asymmetric centers such as fexofenadine, cetirizine, verapamil, fluoxetine, levalbutarol, and amphetamine, for example, have been separated and developed as individual drugs. These stereoisomers have different therapeutic activity, and each isomer has contributed differently with respect to its formulation's pharmacologic activity, side effects, and toxicity. The present overview discusses chirality among a select group of cardiovascular drugs, their stereochemical synthesis/preparation, isolation techniques using chiral chromatography, methods for confirmation of their enantiomeric purity, pharmacodynamics, and pharmacokinetics. Chirality has been visualized as an important factor in cardiovascular research. It is also becoming evident in other areas of therapeutics.

  13. Chirality and gravitational parity violation.

    Science.gov (United States)

    Bargueño, Pedro

    2015-06-01

    In this review, parity-violating gravitational potentials are presented as possible sources of both true and false chirality. In particular, whereas phenomenological long-range spin-dependent gravitational potentials contain both truly and falsely chiral terms, it is shown that there are models that extend general relativity including also coupling of fermionic degrees of freedom to gravity in the presence of torsion, which give place to short-range truly chiral interactions similar to that usually considered in molecular physics. Physical mechanisms which give place to gravitational parity violation together with the expected size of the effects and their experimental constraints are discussed. Finally, the possible role of parity-violating gravity in the origin of homochirality and a road map for future research works in quantum chemistry is presented.

  14. Synthetic Applications of Chiral Furanboronate

    Institute of Scientific and Technical Information of China (English)

    CHAN KinFai; WONG Henry N,C.

    2001-01-01

    @@ We recently uncovered that consecutive reactions of chiral furfural-boronate 1 with a lithium alkoxide and a nucleophile led to the formation of alcohols 2 with good diastereoselection in favor of S-configuration at the newly generated chiral carbon. In addition, it was also found that 2a and 2b were chromatographically separable on a silica gel column. This reaction is believed to involve a tetrahedral borate intermediate, as can be substantiated by 11BNMR spectroscopic studies. Chiral furanmethanolboronates 2a(or 2b) underwent a palladium-catalyzed Suzuki coupling to form enantiomerically pure furans 3, which can be further converted to the synthetically useful hydroxypyranones 4.1,2,3 In addition, Mukaiyama reaction of 1 also led to chromatographically separable diastereomeric aldol-products. The scope and limitation of these conversions will be discussed.

  15. Synthetic Applications of Chiral Furanboronate

    Institute of Scientific and Technical Information of China (English)

    CHAN; KinFai

    2001-01-01

    We recently uncovered that consecutive reactions of chiral furfural-boronate 1 with a lithium alkoxide and a nucleophile led to the formation of alcohols 2 with good diastereoselection in favor of S-configuration at the newly generated chiral carbon. In addition, it was also found that 2a and 2b were chromatographically separable on a silica gel column. This reaction is believed to involve a tetrahedral borate intermediate, as can be substantiated by 11BNMR spectroscopic studies. Chiral furanmethanolboronates 2a(or 2b) underwent a palladium-catalyzed Suzuki coupling to form enantiomerically pure furans 3, which can be further converted to the synthetically useful hydroxypyranones 4.1,2,3 In addition, Mukaiyama reaction of 1 also led to chromatographically separable diastereomeric aldol-products. The scope and limitation of these conversions will be discussed.  ……

  16. Chiral separation of agricultural fungicides.

    Science.gov (United States)

    Pérez-Fernández, Virginia; García, Maria Ángeles; Marina, Maria Luisa

    2011-09-23

    Fungicides are very important and diverse environmental and agricultural concern species. Their determination in commercial formulations or environmental matrices, requires highly efficient, selective and sensitive methods. A significant number of these chemicals are chiral with the activity residing usually in one of the enantiomers. The different toxicological and degradation behavior observed in many cases for fungicide enantiomers, results in the need to investigate them separately. For this purpose, separation techniques such as GC, HPLC, supercritical fluid chromatography (SFC) and CE have widely been employed although, at present, HPLC still dominates chromatographic chiral analysis of fungicides. This review covers the literature concerning the enantiomeric separation of fungicides usually employed in agriculture grouping the chiral separation methodologies developed for their analysis in environmental, biological, and food samples.

  17. Novel Chiral Auxiliaries of BIAZOLs

    Institute of Scientific and Technical Information of China (English)

    CHEN; Arh-Hwang

    2001-01-01

    Asymmetric catalysis is one of the most challenging and formidable endeavor in organic synthesis. The development of chiral auxiliaries is a key in the asymmetric catalysis. Azulenoids, a parent structure of bicyclo[5.3.0]decapentaene with 10 πelectrons, are useful as dye materials, medical treatment of inflammation and hypertension, and the development of liquid crystals. In continuing to investigate synthetic application of azulenoids, we have studied to develop novel chiral auxiliaries of BIAZOLs. The BIAZOLs were synthesized from dicyclopentadiene and characterized using spectroscopies.  ……

  18. Novel Chiral Auxiliaries of BIAZOLs

    Institute of Scientific and Technical Information of China (English)

    CHEN Arh-Hwang; YUAN Shou-Bin; CHIU Shu-Ching

    2001-01-01

    @@ Asymmetric catalysis is one of the most challenging and formidable endeavor in organic synthesis. The development of chiral auxiliaries is a key in the asymmetric catalysis. Azulenoids, a parent structure of bicyclo[5.3.0]decapentaene with 10 πelectrons, are useful as dye materials, medical treatment of inflammation and hypertension, and the development of liquid crystals. In continuing to investigate synthetic application of azulenoids, we have studied to develop novel chiral auxiliaries of BIAZOLs. The BIAZOLs were synthesized from dicyclopentadiene and characterized using spectroscopies.

  19. Asymmetric Synthesis via Chiral Aziridines

    DEFF Research Database (Denmark)

    Tanner, David Ackland; Harden, Adrian; Wyatt, Paul

    1996-01-01

    A series of chiral bis(aziridines) has been synthesised and evaluated as chelating ligands for a variety of asymmetric transformations mediated by metals [Os (dihydroxylation), Pd (allylic alkylation) Cu (cyclopropanation and aziridination, Li (1,2-addition of organolithiums to imines)]. In the b......A series of chiral bis(aziridines) has been synthesised and evaluated as chelating ligands for a variety of asymmetric transformations mediated by metals [Os (dihydroxylation), Pd (allylic alkylation) Cu (cyclopropanation and aziridination, Li (1,2-addition of organolithiums to imines...

  20. Collisions in Chiral Kinetic Theory

    CERN Document Server

    Chen, Jing-Yuan; Stephanov, Mikhail A

    2015-01-01

    Using a covariant formalism, we construct a chiral kinetic theory Lorentz invariant to order $\\mathcal O(\\hbar)$ which includes collisions. We find a new contribution to the particle number current due to the side jumps required by the conservation of angular momentum during collisions. We also find a conserved symmetric stress-energy tensor as well as the $H$-function obeying Boltzmann's $H$-theorem. We demonstrate their use by finding a general equilibrium solution and the values of the anomalous transport coefficients characterizing chiral vortical effect.

  1. Strange chiral nucleon form factors

    CERN Document Server

    Hemmert, T R; Meißner, Ulf G; Hemmert, Thomas R.; Kubis, Bastian; Meissner, Ulf-G.

    1999-01-01

    We investigate the strange electric and magnetic form factors of the nucleon in the framework of heavy baryon chiral perturbation theory to third order in the chiral expansion. All counterterms can be fixed from data. In particular, the two unknown singlet couplings can be deduced from the parity-violating electron scattering experiments performed by the SAMPLE and the HAPPEX collaborations. Within the given uncertainties, our analysis leads to a small and positive electric strangeness radius, $ = (0.05 \\pm 0.16) fm^2$. We also deduce the consequences for the upcoming MAMI A4 experiment.

  2. Corolla chirality does not contribute to directed pollen movement in Hypericum perforatum (Hypericaceae): mirror image pinwheel flowers function as radially symmetric flowers in pollination.

    Science.gov (United States)

    Diller, Carolina; Fenster, Charles B

    2016-07-01

    Corolla chirality, the pinwheel arrangement of petals within a flower, is found throughout the core eudicots. In 15 families, different chiral type flowers (i.e., right or left rotated corolla) exist on the same plant, and this condition is referred to as unfixed/enantiomorphic corolla chirality. There are no investigations on the significance of unfixed floral chirality on directed pollen movement even though analogous mirror image floral designs, for example, enantiostyly, has evolved in response to selection to direct pollinator and pollen movement. Here, we examine the role of corolla chirality on directing pollen transfer, pollinator behavior, and its potential influence on disassortative mating. We quantified pollen transfer and pollinator behavior and movement for both right and left rotated flowers in two populations of Hypericum perforatum. In addition, we quantified the number of right and left rotated flowers at the individual level. Pollinators were indifferent to corolla chirality resulting in no difference in pollen deposition between right and left flowers. Corolla chirality had no effect on pollinator and pollen movement between and within chiral morphs. Unlike other mirror image floral designs, corolla chirality appears to play no role in promoting disassortative mating in this species.

  3. K stability and stability of chiral ring

    CERN Document Server

    Collins, Tristan C; Yau, Shing-Tung

    2016-01-01

    We define a notion of stability for chiral ring of four dimensional N=1 theory by introducing test chiral rings and generalized a maximization. We conjecture that a chiral ring is the chiral ring of a superconformal field theory if and only if it is stable. We then study N=1 field theory derived from D3 branes probing a three-fold singularity X, and show that the K stability which implies the existence of Ricci-flat conic metric on X is equivalent to the stability of chiral ring of the corresponding field theory.

  4. Thermal chiral vortical and magnetic waves: new excitation modes in chiral fluids

    CERN Document Server

    Kalaydzhyan, Tigran

    2016-01-01

    In certain circumstances, chiral (parity-violating) medium can be described hydrodynamically as a chiral fluid with microscopic quantum anomalies. Possible examples of such systems include strongly coupled quark-gluon plasma, liquid helium 3He-A, neutron stars and the Early Universe. We study first-order hydrodynamics of a chiral fluid on a vortex background and in a external magnetic field. We show that there are two previously undiscovered modes describing heat waves propagating along the vortex and magnetic field. We call them the Thermal Chiral Vortical Wave and Thermal Chiral Magnetic Wave. We also identify known gapless excitations of density, the chiral vortical and chiral magnetic waves. We demonstrate that the velocity of the chiral vortical wave is zero, when the full hydrodynamic framework is applied, and hence the excitation reduces to a charge diffusion mode or is completely absent. We also correct the dispersion relation for the chiral magnetic wave.

  5. Chiral magnetic plasmons in anomalous relativistic matter

    CERN Document Server

    Gorbar, E V; Shovkovy, I A; Sukhachov, P O

    2016-01-01

    The chiral plasmon modes of relativistic matter in background magnetic and strain-induced pseudomagnetic fields are studied in detail using the consistent chiral kinetic theory. The results reveal a number of anomalous features of these chiral magnetic and pseudomagnetic plasmons that could be used to identify them in experiment. In a system with nonzero electric (chiral) chemical potential, the background magnetic (pseudomagnetic) fields not only modify the values of the plasmon frequencies in the long wavelength limit, but also affect the qualitative dependence on the wave-vector. Similar modifications can be also induced by the chiral shift parameter in Weyl materials. Interestingly, even in the absence of the chiral shift and external fields, the chiral chemical potential alone leads to a splitting of plasmon energies at linear order in the wave vector.

  6. Algebraic study of chiral anomalies

    Indian Academy of Sciences (India)

    Juan Mañes; Raymond Stora; Bruno Zumino

    2012-06-01

    The algebraic structure of chiral anomalies is made globally valid on non-trivial bundles by the introduction of a fixed background connection. Some of the techniques used in the study of the anomaly are improved or generalized, including a systematic way of generating towers of ‘descent equations’.

  7. Chiral Perturbation Theory and Unitarization

    CERN Document Server

    Ruiz-Arriola, E; Nieves, J; Peláez, J R

    2000-01-01

    We review our recent work on unitarization and chiral perturbation theory both in the $\\pi\\pi$ and the $\\pi N$ sectors. We pay particular attention to the Bethe-Salpeter and Inverse Amplitude unitarization methods and their recent applications to $\\pi\\pi$ and $\\pi N$ scattering.

  8. Single chirality through crystal grinding

    NARCIS (Netherlands)

    Noorduin, W.L.

    2010-01-01

    The properties of chiral molecules in living organisms can be different for left- and right-handed molecules. Therefore, ways to produce molecules of single handedness are of paramount importance, especially for economical, high yielding processes to synthesize pharmaceutical compounds that must be

  9. Chiral non-Fermi liquids

    Science.gov (United States)

    Sur, Shouvik; Lee, Sung-Sik

    2014-07-01

    A non-Fermi liquid state without time-reversal and parity symmetries arises when a chiral Fermi surface is coupled with a soft collective mode in two space dimensions. The full Fermi surface is described by a direct sum of chiral patch theories, which are decoupled from each other in the low-energy limit. Each patch includes low-energy excitations near a set of points on the Fermi surface with a common tangent vector. General patch theories are classified by the local shape of the Fermi surface, the dispersion of the critical boson, and the symmetry group, which form the data for distinct universality classes. We prove that a large class of chiral non-Fermi liquid states exists as stable critical states of matter. For this, we use a renormalization group scheme where low-energy excitations of the Fermi surface are interpreted as a collection of (1+1)-dimensional chiral fermions with a continuous flavor labeling the momentum along the Fermi surface. Due to chirality, the Wilsonian effective action is strictly UV finite. This allows one to extract the exact scaling exponents although the theories flow to strongly interacting field theories at low energies. In general, the low-energy effective theory of the full Fermi surface includes patch theories of more than one universality classes. As a result, physical responses include multiple universal components at low temperatures. We also point out that, in quantum field theories with extended Fermi surface, a noncommutative structure naturally emerges between a coordinate and a momentum which are orthogonal to each other. We show that the invalidity of patch description for Fermi liquid states is tied with the presence of UV/IR mixing associated with the emergent noncommutativity. On the other hand, UV/IR mixing is suppressed in non-Fermi liquid states due to UV insensitivity, and the patch description is valid.

  10. Nuclear chiral dynamics and thermodynamics

    Science.gov (United States)

    Holt, Jeremy W.; Kaiser, Norbert; Weise, Wolfram

    2013-11-01

    This presentation reviews an approach to nuclear many-body systems based on the spontaneously broken chiral symmetry of low-energy QCD. In the low-energy limit, for energies and momenta small compared to a characteristic symmetry breaking scale of order 1 GeV, QCD is realized as an effective field theory of Goldstone bosons (pions) coupled to heavy fermionic sources (nucleons). Nuclear forces at long and intermediate distance scales result from a systematic hierarchy of one- and two-pion exchange processes in combination with Pauli blocking effects in the nuclear medium. Short distance dynamics, not resolved at the wavelengths corresponding to typical nuclear Fermi momenta, are introduced as contact interactions between nucleons. Apart from a set of low-energy constants associated with these contact terms, the parameters of this theory are entirely determined by pion properties and low-energy pion-nucleon scattering observables. This framework (in-medium chiral perturbation theory) can provide a realistic description of both isospin-symmetric nuclear matter and neutron matter, with emphasis on the isospin-dependence determined by the underlying chiral NN interaction. The importance of three-body forces is emphasized, and the role of explicit Δ(1232)-isobar degrees of freedom is investigated in detail. Nuclear chiral thermodynamics is developed and a calculation of the nuclear phase diagram is performed. This includes a successful description of the first-order phase transition from a nuclear Fermi liquid to an interacting Fermi gas and the coexistence of these phases below a critical temperature Tc. Density functional methods for finite nuclei based on this approach are also discussed. Effective interactions, their density dependence and connections to Landau Fermi liquid theory are outlined. Finally, the density and temperature dependences of the chiral (quark) condensate are investigated.

  11. Chirality of Single-Handed Twisted Titania Tubular Nanoribbons Prepared Through Sol-gel Transcription.

    Science.gov (United States)

    Wang, Sibing; Zhang, Chuanyong; Li, Yi; Li, Baozong; Yang, Yonggang

    2015-08-01

    Single-handed twisted titania tubular nanoribbons were prepared through sol-gel transcription using a pair of enantiomers. Handedness was controlled by that of the template. The obtained samples were characterized using field-emission electron microscopy, transmission electron microscopy, diffuse reflectance circular dichroism (DRCD), and X-ray diffraction. The DRCD spectra indicated that the titania nanotubes exhibit optical activity. Although the tubular structure was destroyed after being calcined at 700 °C for 2.0 h, DRCD signals were still identified. However, the DRCD signals disappeared after being calcined at 1000 °C for 2.0 h. The optical activity of titania was proposed to be due to chiral defects. Previous results showed that straight titania tubes could be used as asymmetric autocatalysts, indicating that titania exhibit chirality at the angstrom level. Herein, it was found that they also exhibit DRCD signals, indicating that there are no obvious relationships between morphology at the nano level and chirality at the angstrom level. The nanotube chirality should originate from the chiral defects on the nanotube inner surface. The Fourier transform infrared spectra indicated that the chirality of the titania was transferred from the gelators through the hydrogen bonding between N-H and Ti-OH.

  12. Chiral metamaterials: retrieval of the effective parameters with and without substrate.

    Science.gov (United States)

    Zhao, Rongkuo; Koschny, Thomas; Soukoulis, Costas M

    2010-07-01

    After the prediction that strong enough optical activity may result in negative refraction and negative reflection, more and more artificial chiral metamaterials were designed and fabricated at difference frequency ranges from microwaves to optical waves. Therefore, a simple and robust method to retrieve the effective constitutive parameters for chiral metamaterials is urgently needed. Here, we analyze the wave propagation in chiral metamaterials and follow the regular retrieval procedure for ordinary metamaterials and apply it in chiral metamaterial slabs. Then based on the transfer matrix technique, the parameter retrieval is extended to treat samples with not only the substrate but also the top layers. After the parameter retrieval procedure, we take two examples to check our method and study how the substrate influences on the thin chiral metamaterials slabs. We find that the substrate may cause the homogeneous slab to be inhomogeneous, i.e. the reflections in forward and backward directions are different. However, the chiral metamaterial where the resonance element is embedded far away from the substrate is insensitive to the substrate.

  13. Molecular chirality and chiral capsule-type dimer formation of cyclic triamides via hydrogen-bonding interactions.

    Science.gov (United States)

    Fujimoto, Noriko; Matsumura, Mio; Azumaya, Isao; Nishiyama, Shizuka; Masu, Hyuma; Kagechika, Hiroyuki; Tanatani, Aya

    2012-05-18

    Chiral properties of bowl-shaped cyclic triamides bearing functional groups with hydrogen-bonding ability were examined. Chiral induction of cyclic triamide 3a was observed by addition of chiral amine in solution, and chiral separation was achieved by simple crystallization to afford chiral capsule-type dimer structure of 4a.

  14. Chiral extraction of ketoprofen enantiomers with chiral selector tartaric esters

    Institute of Scientific and Technical Information of China (English)

    ZHOU Dan; LIU Jia-jia; TANG Ke-wen; HUANG Ke-long

    2007-01-01

    Distribution behavior of ketoprofen enantiomers was examined in methanol aqueous and organic solvent mixture containing tartaric esters. The influence of length of alkyl chain of tartaric esters, concentration of L-tartaric esters and methanol aqueous, kind of organic solvent on partition ratio and separation factors was investigated. The results show that L-tartaric and D-tartaric esters have different chiral recognition abilities. S-ketoprofen is easily extracted by L-tartaric esters, and R-ketoprofen is easily extracted by D-tartaric esters. L-tartaric esters form more stable diastereomeric complexes with S-enantiomer than that with R-enantiomer. This distribution behavior is consistent with chiral recognition mechanism. With the increase of the concentration of tartaric ester from 0 to 0.3 mol/L, partition coefficient K and separation factor α increase. Also, the kind of organic solvent and the concentration of the methanol aqueous have significant influence on K and α.

  15. Spectral study of a chiral limit without chiral condensate

    CERN Document Server

    Bietenholz, Wolfgang

    2009-01-01

    Random Matrix Theory (RMT) has elaborated successful predictions for Dirac spectra in field theoretical models. However, a generic assumption by RMT has been a non-vanishing chiral condensate $\\Sigma$ in the chiral limit. Here we consider the 2-flavour Schwinger model, where this assumption does not hold. We simulated this model with dynamical overlap hypercube fermions, and entered terra incognita by analysing this Dirac spectrum. The usual RMT prediction for the unfolded level spacing distribution in a unitary ensemble is precisely confirmed. The microscopic spectrum does not perform a Banks-Casher plateau. Instead the obvious expectation is a density of the lowest eigenvalue $\\lambda_{1}$ which increases $\\propto \\lambda_{1}^{1/3}$. That would correspond to a scale-invariant parameter $\\propto \\lambda V^{3/4}$, which is, however, incompatible with our data. Instead we observe to high precision a scale-invariant parameter $z \\propto \\lambda V^{5/8}$. This surprising result implies a microscopic spectral den...

  16. Chiral Lagrangian and chiral quark model from confinement in QCD

    CERN Document Server

    Simonov, Yu A

    2015-01-01

    The effective chiral Lagrangian in both nonlocal form $L_{ECCL}$ and standard local form $L_{ECL}$ are derived in QCD using the confining kernel, obtained in the vacuum correlator formalism. As a result all coefficients of $L_{ECL}$ can be computed via $q\\bar q$ Green's functions. In the $p^2$ order of $L_{ECL}$ one obtains GOR relations and quark decay constants $f_a$ are calculated $a=1,...8$, while in the $p^4$ order the coefficients $L_1, L_2, L_3,L_4, L_5, L_6$ are obtained in good agreement with the values given by data. The chiral quark model is shown to be a simple consequence of $L_{ECCL}$ with defined coefficients. It is demonstrated that $L_{ECCL}$ gives an extension of the limiting low-energy Lagrangian $L_{ECL}$ to arbitrary momenta.

  17. Mechanism of chirality conversion by periodic change of temperature: Role of chiral clusters

    Science.gov (United States)

    Katsuno, Hiroyasu; Uwaha, Makio

    2016-01-01

    By grinding crystals in a solution, the chirality of crystal structure (and the molecular chirality for the case of chiral molecules as well) can be converted, and the cause of the phenomenon is attributed to crystal growth with chiral clusters. We show that the recently found chirality conversion with a periodic change of temperature can also be explained by crystal growth with chiral clusters. With the use of a generalized Becker-Döring model, which includes enantio-selective incorporation of small chiral clusters to large solid clusters, the change of cluster distribution and the mass flow between clusters are studied. The chiral clusters act as a reservoir to pump out the minority species to the majority, and the exponential amplification of the enantiomeric excess found in the experiment is reproduced in the numerical calculation.

  18. ENANTIOMERIC RATIOS OF CHIRAL PCB ATROPISOMERS IN RADIODATED SEDIMENT CORES

    Science.gov (United States)

    Enantiomeric ratios (ERs)) of chiral polychlorinated biphenyl (PCB) atropisomers were quantified in radiodated sediment cores of Lake Hartwell SC, a reservoir heavily impacted by PCBS, to study spatial and temporal changes in chirality. A chiral analysis of cores showed accumulat...

  19. Asymmetric synthesis using chiral-encoded metal

    Science.gov (United States)

    Yutthalekha, Thittaya; Wattanakit, Chularat; Lapeyre, Veronique; Nokbin, Somkiat; Warakulwit, Chompunuch; Limtrakul, Jumras; Kuhn, Alexander

    2016-08-01

    The synthesis of chiral compounds is of crucial importance in many areas of society and science, including medicine, biology, chemistry, biotechnology and agriculture. Thus, there is a fundamental interest in developing new approaches for the selective production of enantiomers. Here we report the use of mesoporous metal structures with encoded geometric chiral information for inducing asymmetry in the electrochemical synthesis of mandelic acid as a model molecule. The chiral-encoded mesoporous metal, obtained by the electrochemical reduction of platinum salts in the presence of a liquid crystal phase and the chiral template molecule, perfectly retains the chiral information after removal of the template. Starting from a prochiral compound we demonstrate enantiomeric excess of the (R)-enantiomer when using (R)-imprinted electrodes and vice versa for the (S)-imprinted ones. Moreover, changing the amount of chiral cavities in the material allows tuning the enantioselectivity.

  20. Molecular chirality: language, history, and significance.

    Science.gov (United States)

    Gal, Joseph

    2013-01-01

    In this chapter some background material concerning molecular chirality and enantiomerism is presented. First some basic chemical-molecular aspects of chirality are reviewed, after which certain relevant terminology whose use in the literature has been problematic is discussed. Then an overview is provided of some of the early discoveries that laid the foundations of the science of molecular chirality in chemistry and biology, including the discovery of the phenomenon of molecular chirality by L. Pasteur, the proposals for the asymmetric carbon atom by J.H. van 't Hoff and J.A. Lebel, Pasteur's discovery of biological enantioselectivity, the discovery of enantioselectivity at biological receptors by A. Piutti, the studies of enzymatic stereoselectivity by E. Fischer, and the work on enantioselectivity in pharmacology by A. Cushny. Finally, the role of molecular chirality in pharmacotherapy and new-drug development, arguably one of the main driving forces for the current intense interest in the phenomenon of molecular chirality, is discussed.

  1. Symmetries of Ginsparg-Wilson Chiral Fermions

    CERN Document Server

    Mandula, Jeffrey E

    2009-01-01

    The group structure of the variant chiral symmetry discovered by Luscher in the Ginsparg-Wilson description of lattice chiral fermions is analyzed. It is shown that the group contains an infinite number of linearly independent symmetry generators, and the Lie algebra is given explicitly. CP is an automorphism of this extended chiral group, and the CP transformation properties of the symmetry generators are found. The group has an infinite-parameter subgroup, and the factor group whose elements are its cosets is isomorphic to the continuum chiral symmetry group. Features of the currents associated with these symmetries are discussed, including the fact that some different, non-commuting symmetry generators lead to the same Noether current. These are universal features of lattice chiral fermions based on the Ginsparg-Wilson relation; they occur in the overlap, domain-wall, and perfect-action formulations. In a solvable example - free overlap fermions - these non-canonical elements of lattice chiral symmetry are...

  2. Enantioselective recognition at mesoporous chiral metal surfaces

    Science.gov (United States)

    Wattanakit, Chularat; Côme, Yémima Bon Saint; Lapeyre, Veronique; Bopp, Philippe A.; Heim, Matthias; Yadnum, Sudarat; Nokbin, Somkiat; Warakulwit, Chompunuch; Limtrakul, Jumras; Kuhn, Alexander

    2014-02-01

    Chirality is widespread in natural systems, and artificial reproduction of chiral recognition is a major scientific challenge, especially owing to various potential applications ranging from catalysis to sensing and separation science. In this context, molecular imprinting is a well-known approach for generating materials with enantioselective properties, and it has been successfully employed using polymers. However, it is particularly difficult to synthesize chiral metal matrices by this method. Here we report the fabrication of a chirally imprinted mesoporous metal, obtained by the electrochemical reduction of platinum salts in the presence of a liquid crystal phase and chiral template molecules. The porous platinum retains a chiral character after removal of the template molecules. A matrix obtained in this way exhibits a large active surface area due to its mesoporosity, and also shows a significant discrimination between two enantiomers, when they are probed using such materials as electrodes.

  3. Negative refractive index in chiral metamaterials.

    Science.gov (United States)

    Zhang, Shuang; Park, Yong-Shik; Li, Jensen; Lu, Xinchao; Zhang, Weili; Zhang, Xiang

    2009-01-16

    We experimentally demonstrate a chiral metamaterial exhibiting negative refractive index at terahertz frequencies. The presence of strong chirality in the terahertz metamaterial lifts the degeneracy for the two circularly polarized waves and allows for the achievement of negative refractive index without requiring simultaneously negative permittivity and negative permeability. The realization of terahertz chiral negative index metamaterials offers opportunities for investigation of their novel electromagnetic properties, such as negative refraction and negative reflection, as well as important terahertz device applications.

  4. Chiral Plasmonic Nanostructures on Achiral Nanopillars

    Science.gov (United States)

    2013-10-10

    0704-0188 3. DATES COVERED (From - To) - UU UU UU UU Approved for public release; distribution is unlimited. Chiral Plasmonic Nanostructures on Achiral...Nanopillars Chirality of plasmonic films can be strongly enhanced by threedimensional (3D) out-of-plane geometries. The complexity of lithographic...methods currently used to produce such structures and other methods utilizing chiral templates impose limitations on spectral windows of chiroptical

  5. Chirality and the angular momentum of light

    Science.gov (United States)

    Cameron, Robert P.; Götte, Jörg B.; Barnett, Stephen M.; Yao, Alison M.

    2017-02-01

    Chirality is exhibited by objects that cannot be rotated into their mirror images. It is far from obvious that this has anything to do with the angular momentum of light, which owes its existence to rotational symmetries. There is nevertheless a subtle connection between chirality and the angular momentum of light. We demonstrate this connection and, in particular, its significance in the context of chiral light-matter interactions. This article is part of the themed issue 'Optical orbital angular momentum'.

  6. Chiral phases of fundamental and adjoint quarks

    Energy Technology Data Exchange (ETDEWEB)

    Natale, A. A. [Centro de Ciências Naturais e Humanas, Universidade Federal do ABC 09210-170, Santo André, SP (Brazil); Instituto de Física Teórica - UNESP Rua Dr. Bento T. Ferraz, 271, Bl.II - 01140-070, São Paulo, SP (Brazil)

    2016-01-22

    We consider a QCD chiral symmetry breaking model where the gap equation contains an effective confining propagator and a dressed gluon propagator with a dynamically generated mass. This model is able to explain the ratios between the chiral transition and deconfinement temperatures in the case of fundamental and adjoint quarks. It also predicts the recovery of the chiral symmetry for a large number of quarks (n{sub f} ≈ 11 – 13) in agreement with lattice data.

  7. Infinite Chiral Symmetry in Four Dimensions

    CERN Document Server

    Beem, Christopher; Liendo, Pedro; Peelaers, Wolfger; Rastelli, Leonardo; van Rees, Balt C

    2015-01-01

    We describe a new correspondence between four-dimensional conformal field theories with extended supersymmetry and two-dimensional chiral algebras. The meromorphic correlators of the chiral algebra compute correlators in a protected sector of the four-dimensional theory. Infinite chiral symmetry has far-reaching consequences for the spectral data, correlation functions, and central charges of any four-dimensional theory with ${\\mathcal N}=2$ superconformal symmetry.

  8. A spectral route to determining chirality

    DEFF Research Database (Denmark)

    Pedersen, Jesper Goor; Mortensen, Asger

    2009-01-01

    We show how one-dimensional structured media can be used to measure chirality, via the spectral shift of the photonic band gap edges. Analytically, we show that a chiral contrast can, in some cases, be mapped unto an index contrast, thereby greatly simplifying the analysis of such structures. Using...... this mapping, we derive a first-order shift of the band gap edges with chirality. Potentially, this effect could be used for measuring enantiomeric excess....

  9. Chiral Separation of Erythromycin as a New Chiral Selector on CE

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Erythromycin as a new chiral selector was first used for chrial separation of four derivatives of biphenyldimethylester enantiomers on CE. The influence of pH, the chiral selector concentration and organic modifiers were preliminarily studied. Experiments show that the erythromycin as chiral selector is useful to CE.

  10. Chiral Induction with Chiral Conformational Switches in the Limit of Low "Sergeants to Soldiers" Ratio

    DEFF Research Database (Denmark)

    Nuermaimaiti, Ajiguli; Bombis, Christian; Knudsen, Martin Markvard

    2014-01-01

    " mechanism for an oligo(phenylene ethynylene) based chiral conformational switch by coadsorbing it with an intrinsically chiral seed on Au(111). Through statistical analysis of scanning tunneling microscopy (STM) data we demonstrate successful chiral induction with a very low concentration of seeding...

  11. Nucleon Properties and Restoration of Chiral Symmetry at Finite\

    CERN Document Server

    Christov, C V; Göke, K; Christov, Chr.V.

    1993-01-01

    Modifications of baryon properties due to the restoration of the chiral symmetry in an external hot and dense baryon medium are investigated in an effective chiral quark-meson theory. The nucleon arises as a soliton of the Gell-Mann - L\\'evi $\\zs$-model, the parameters of which are chosen to be the medium-modified meson values evaluated within the Nambu - Jona-Lasinio model. The nucleon properties are obtained by means of variational projection techniques. The nucleon form factors as well as the nucleon delta transition form factors are evaluated for various densities and temperatures of the medium. Similar to the chiral phase transition line the critical curve in the $T-\\zr$ plane for delocalization of the nucleon is non-monotonic and this feature is reflected in all nucleon properties. At medium densities of about $(2-3) \\rnm$ the baryonic phase exists only at intermediate temperatures. For finite temperature and densities the nucleon form factors get strongly reduced at finite transfer momenta.

  12. Staggered chiral random matrix theory

    CERN Document Server

    Osborn, James C

    2010-01-01

    We present a random matrix theory (RMT) for the staggered lattice QCD Dirac operator. The staggered RMT is equivalent to the zero-momentum limit of the staggered chiral Lagrangian and includes all taste breaking terms at their leading order. This is an extension of previous work which only included some of the taste breaking terms. We will also present some results for the taste breaking contributions to the partition function and the Dirac eigenvalues.

  13. On the gauging of chiral bosons

    CERN Document Server

    Wotzasek, C

    1995-01-01

    We study the coupling of chiral bosons to external electromagnetic fields. It is observed that a naive gauging procedure leaves the gauge invariant chirality condition incompatible with the field equations. We propose the use of this feature as a consistency test to select the appropriate way to perform the gauge coupling. We verify that among all the possible gauging schemes, only the coupling of gauge fields with chiral currents passes the consistency test. As an application, we use this gauging scheme to show how the introduction of a gauge field becomes necessary in order to sold together a right and a left chiral boson.

  14. Effects from inhomogeneities in the chiral transition

    CERN Document Server

    Taketani, B G; Taketani, Bruno G.; Fraga, Eduardo S.

    2006-01-01

    We consider an approximation procedure to evaluate the finite-temperature one-loop fermionic density in the presence of a chiral background field which systematically incorporates effects from inhomogeneities in the chiral field through a derivative expansion. We apply the method to the case of a simple low-energy effective chiral model which is commonly used in the study of the chiral phase transition, the linear sigma-model coupled to quarks. The modifications in the effective potential and their consequences for the bubble nucleation process are discussed.

  15. Laser Writing of Multiscale Chiral Polymer Metamaterials

    Directory of Open Access Journals (Sweden)

    E. P. Furlani

    2012-01-01

    Full Text Available A new approach to metamaterials is presented that involves laser-based patterning of novel chiral polymer media, wherein chirality is realized at two distinct length scales, intrinsically at the molecular level and geometrically at a length scale on the order of the wavelength of the incident field. In this approach, femtosecond-pulsed laser-induced two-photon lithography (TPL is used to pattern a photoresist-chiral polymer mixture into planar chiral shapes. Enhanced bulk chirality can be realized by tuning the wavelength-dependent chiral response at both the molecular and geometric level to ensure an overlap of their respective spectra. The approach is demonstrated via the fabrication of a metamaterial consisting of a two-dimensional array of chiral polymer-based L-structures. The fabrication process is described and modeling is performed to demonstrate the distinction between molecular and planar geometric-based chirality and the effects of the enhanced multiscale chirality on the optical response of such media. This new approach to metamaterials holds promise for the development of tunable, polymer-based optical metamaterials with low loss.

  16. Supramolecular Chirality in Dynamic Coordination Chemistry

    Directory of Open Access Journals (Sweden)

    Hiroyuki Miyake

    2014-10-01

    Full Text Available Labile metal complexes have a useful coordination bond; which is weaker than a covalent C–C bond and is reversibly and dynamically formed and dissociated. Such labile metal complexes also can be used to construct chiral shapes and offer dynamic conversion of chiral molecular shapes in response to external stimuli. This review provides recent examples of chirality induction and describes the dynamic conversion systems produced by chiral metal complexes including labile metal centers, most of which respond to external stimuli by exhibiting sophisticated conversion phenomena.

  17. Chiral methyl-branched pheromones.

    Science.gov (United States)

    Ando, Tetsu; Yamakawa, Rei

    2015-07-01

    Insect pheromones are some of the most interesting natural products because they are utilized for interspecific communication between various insects, such as beetles, moths, ants, and cockroaches. A large number of compounds of many kinds have been identified as pheromone components, reflecting the diversity of insect species. While this review deals only with chiral methyl-branched pheromones, the chemical structures of more than one hundred non-terpene compounds have been determined by applying excellent analytical techniques. Furthermore, their stereoselective syntheses have been achieved by employing trustworthy chiral sources and ingenious enantioselective reactions. The information has been reviewed here not only to make them available for new research but also to understand the characteristic chemical structures of the chiral pheromones. Since biosynthetic studies are still limited, it might be meaningful to examine whether the structures, particularly the positions and configurations of the branched methyl groups, are correlated with the taxonomy of the pheromone producers and also with the function of the pheromones in communication systems.

  18. Chiral symmetry breaking and monopoles

    CERN Document Server

    Di Giacomo, Adriano; Pucci, Fabrizio

    2015-01-01

    To understand the relation between the chiral symmetry breaking and monopoles, the chiral condensate which is the order parameter of the chiral symmetry breaking is calculated in the $\\overline{\\mbox{MS}}$ scheme at 2 [GeV]. First, we add one pair of monopoles, varying the monopole charges $m_{c}$ from zero to four, to SU(3) quenched configurations by a monopole creation operator. The low-lying eigenvalues of the Overlap Dirac operator are computed from the gauge links of the normal configurations and the configurations with additional monopoles. Next, we compare the distributions of the nearest-neighbor spacing of the low-lying eigenvalues with the prediction of the random matrix theory. The low-lying eigenvalues not depending on the scale parameter $\\Sigma$ are compared to the prediction of the random matrix theory. The results show the consistency with the random matrix theory. Thus, the additional monopoles do not affect the low-lying eigenvalues. Moreover, we discover that the additional monopoles increa...

  19. Pion Form Factor in Chiral Limit of Hard-Wall AdS/QCD Model

    Energy Technology Data Exchange (ETDEWEB)

    Anatoly Radyushkin; Hovhannes Grigoryan

    2007-12-01

    We develop a formalism to calculate form factor and charge density distribution of pion in the chiral limit using the holographic dual model of QCD with hard-wall cutoff. We introduce two conjugate pion wave functions and present analytic expressions for these functions and for the pion form factor. They allow to relate such observables as the pion decay constant and the pion charge electric radius to the values of chiral condensate and hard-wall cutoff scale. The evolution of the pion form factor to large values of the momentum transfer is discussed, and results are compared to existing experimental data.

  20. Modified High Frequency Radial Spin Wave Mode Spectrum in a Chirality-Controlled Nanopillar

    Science.gov (United States)

    Kolthammer, J. E.; Rudge, J.; Choi, B. C.; Hong, Y. K.

    2016-09-01

    Circular magnetic spin valve nanopillars in a dual vortex configuration have dynamic characteristics strongly dependent on the interlayer dipole coupling. We report here on frequency domain properties of such nanopillars obtained by micromagnetic simulations. After the free layer is chirality switched with spin transfer torque, a radial spin wave eigenmode spectrum forms in the free layer with unusually large edge amplitude. The structure of these modes indicate a departure from the magnetostatic processes typically observed experimentally and treated analytically in low aspect ratio isolated disks. Our findings give new details of dynamic chirality control and relxation in nanopillars and raise potential signatures for experiments.

  1. Gold-plated moments of nucleon structure functions in baryon chiral perturbation theory

    CERN Document Server

    Lensky, Vadim; Pascalutsa, Vladimir

    2014-01-01

    We obtain leading- and next-to-leading order predictions of chiral perturbation theory for several prominent moments of nucleon structure functions. These free-parameter free results turn out to be in overall agreement with the available empirical information on all of the considered moments, in the region of low-momentum transfer ($Q^2 < 0.3$ GeV$^2$). Especially surprising is the situation for the $\\delta_{LT}$ moment, which thus far was not reproducible for proton and neutron simultaneously in chiral perturbation theory. This problem, known as the "$\\delta_{LT}$ puzzle," is not seen in the present calculation.

  2. Forward virtual Compton scattering and the Lamb shift in chiral perturbation theory

    CERN Document Server

    Nevado, David

    2007-01-01

    We compute the spin-independent structure functions of the forward virtual-photon Compton tensor of the proton at one loop using heavy baryon chiral perturbation theory and dispersion relations. We study the relation between both approaches. We use these results to generalize some sum rules to virtual photon transfer momentum and relate them with sum rules in deep inelastic scattering. We then compute the leading chiral term of the polarizability correction to the Lamb shift of the hydrogen and muonic hydrogen. We obtain -87.05/n^3 Hz and -0.148/n^3 meV for the correction to the hydrogen and muonic hydrogen Lamb shift respectively.

  3. Synthesis and Chiral Recognition of a New Type of Chiral Calix[4]arene Derivatives

    Institute of Scientific and Technical Information of China (English)

    HE,Yong-Bing; LI,Jian-Feng; XIAO,Yuan-Jing; WEI,Lan-Hua; WU,Xiao-Jun; MENG,Ling-Zhi

    2003-01-01

    Two new chiral calix[4] arenes bearing chiral pendants, which were from by-product of the antibiotic industry, were synthesized and characterized by 1H NMR, MS-FAB and elemental analysis. Studies of 1H NMR of the two calix [4] arene derivatives indicate that they exist in cone conformation in solution. Results of chiral recognition of the two chiral ligands 2a and 2b towards the tartaric acid derivative 3 show that ligand 2a exhibited good chiral recognition abilities compared to ligand 2b.

  4. Chiral metamaterials reduce the attractive Casimir force

    Science.gov (United States)

    Zhao, R.; Koschny, Th.; Economou, E. N.; Soukoulis, C. M.

    2010-08-01

    In our previous work [R. Zhao, J. Zhou, Th. Koschny, E. N. Economou, and C. M. Soukoulis, Phys. Rev. Lett. 103, 103602 (2009)], we demonstrated theoretically that one can obtain repulsive Casimir forces and stable nanolevitations by using chiral metamaterials if the chirality is strong enough. In our recent work [R. Zhao, Th. Koschny, E.N. Economou, and C.M. Soukoulis, Phys. Rev. B 81, 235126 (2010)], we checked some chiral metamaterial designs and found that the artificial chiral metamaterials constructed by passive materials is very difficult to reach the critical chirality to realize repulsive Casimir force. Therefore, in this paper, we give a four-folded rotated Ω-particle chiral metamaterial as an example, use the effective medium approximation to retrieval the constitutive parameters, and take the same procedure as we did before to see how much the chiral metamaterial can reduce the attractive force. It shows that this un-optimized chiral metamaterial can reduce the Casimir attraction by 70%.

  5. LINEARLY POLARIZED PROBES OF SURFACE CHIRALITY

    NARCIS (Netherlands)

    VERBIEST, T; KAURANEN, M; MAKI, JJ; TEERENSTRA, MN; SCHOUTEN, AJ; NOLTE, RJM; PERSOONS, A

    1995-01-01

    We present a new nonlinear optical technique to study surface chirality. We demonstrate experimentally that the efficiency of second-harmonic generation from isotropic chiral surfaces is different for excitation with fundamental light that is +45 degrees and -45 degrees linearly polarized with respe

  6. An Extended Chiral SU(3) Quark Model

    Institute of Scientific and Technical Information of China (English)

    ZHANG Zong-Ye; YU You-Wen; WANG Ping; DAI Lian-Rong

    2003-01-01

    The chiral SU(3) quark model is extended by including the vector meson exchanges to describe the short range interactions. The phase shifts of NN scattering are studied in this model. Compared with the results of the chiral SU(3) quark model in which only the pseudo-scalar and scalar chiralfields are considered, the phase shifts of 1 So wave are obviously improved.

  7. A NEW CHIRAL ALLOTROPE C80

    Institute of Scientific and Technical Information of China (English)

    詹克明

    1994-01-01

    The theoretical prophecy is given on a new chiral allotrope of Fullerene-C80.C80 molecuule should have 3C2 symmetric axes,which should be vertical each othyer.C80 should have two chiral allotropes,13C-NMR spectra of C80 should consist of 20 lines of equal intensity.

  8. Chiral magnetic effect in condensed matter systems

    Science.gov (United States)

    Li, Qiang; Kharzeev, Dmitri E.

    2016-12-01

    The chiral magnetic effect (CME) is the generation of electrical current induced by chirality imbalance in the presence of magnetic field. It is a macroscopic manifestation of the quantum chiral anomaly [S. L. Adler. Axial-vector vertex in spinor electrodynamics. Physical Review, 177, 2426 (1969), J. S. Bell and R. Jackiw. A PCAC puzzle: π 0 γγin the σ-model. Il Nuovo Cimento A, 60, 47-61 (1969)] in systems possessing charged chiral fermions. In quark-gluon plasma containing nearly massless quarks, the chirality imbalance is sourced by the topological transitions. In condensed matter systems, the chiral quasiparticles emerge in gapless semiconductors with two energy bands having pointlike degeneracies opening the path to the study of chiral anomaly [H. B. Nielsen and M. Ninomiya. The Adler-Bell-Jackiw anomaly and Weyl fermions in a crystal. Physics Letters B, 130, 389-396 (1983)]. Recently, these novel materials - so-called Dirac and Weyl semimetals have been discovered experimentally, are suitable for the investigation of the CME in condensed matter experiments. Here we report on the first experimental observation of the CME in a 3D Dirac semimetal ZrTe5 [Q. Li, D. E. Kharzeev, C. Zhang, Y. Huang, I. Pletikosić, A. V. Fedorov, R. D. Zhong, J. A. Schneeloch, G. D. Gu, and T. Valla. Chiral magnetic effect in ZrTe5. Nature Physics (2016) doi:10.1038/nphys3648].

  9. DEVELOPMENT AND REGISTRATION OF CHIRAL DRUGS

    NARCIS (Netherlands)

    WITTE, DT; ENSING, K; FRANKE, JP; DEZEEUW, RA

    1993-01-01

    In this review we describe the impact of chirality on drug development and registration in the United States, Japan and the European Community. Enantiomers may have differences in their pharmacological profiles, and, therefore, chiral drugs ask for special analytical and pharmacological attention du

  10. Quenched chiral perturbation theory to one loop

    NARCIS (Netherlands)

    Colangelo, Gilberto; Pallante, Elisabetta

    1998-01-01

    We calculate the divergences of the generating functional of quenched chiral perturbation theory at one loop, and renormalize the theory by an appropriate definition of the counterterms. We show that the quenched chiral logarithms can be accounted for by defining a renormalized B0 parameter which, a

  11. Chiral Corrections to Nucleon Two- and Three-Point Correlation Functions

    CERN Document Server

    Tiburzi, Brian C

    2015-01-01

    We consider multi-particle contributions to nucleon two- and three-point functions from the perspective of chiral dynamics. Lattice nucleon interpolating operators, which have definite chiral transformation properties, can be mapped into chiral perturbation theory. Using the most common of such operators, we determine pion-nucleon and pion-delta couplings to nucleon two- and three-point correlation functions at leading order in the low-energy expansion. The couplings of pions to nucleons and deltas in two-point functions are consistent with simple phase-space considerations, in accordance with the Lehmann spectral representation. An argument based on available phase space on a torus is utilized to derive the scaling of multiple-pion couplings. While multi-pion states are indeed suppressed, this suppression scales differently with particle number compared to that in infinite volume. For nucleon three-point correlation functions, we investigate the axial-vector current at vanishing momentum transfer. The effect...

  12. Catalytic enantioselective amination of alcohols by the use of borrowing hydrogen methodology: cooperative catalysis by iridium and a chiral phosphoric acid.

    Science.gov (United States)

    Zhang, Yao; Lim, Ching-Si; Sim, Derek Sui Boon; Pan, Hui-Jie; Zhao, Yu

    2014-01-27

    The catalytic asymmetric reduction of ketimines has been explored extensively for the synthesis of chiral amines, with reductants ranging from Hantzsch esters, silanes, and formic acid to H2 gas. Alternatively, the amination of alcohols by the use of borrowing hydrogen methodology has proven a highly atom economical and green method for the production of amines without an external reductant, as the alcohol substrate serves as the H2 donor. A catalytic enantioselective variant of this process for the synthesis of chiral amines, however, was not known. We have examined various transition-metal complexes supported by chiral ligands known for asymmetric hydrogenation reactions, in combination with chiral Brønsted acids, which proved essential for the formation of the imine intermediate and the transfer-hydrogenation step. Our studies led to an asymmetric amination of alcohols to provide access to a wide range of chiral amines with good to excellent enantioselectivity.

  13. Origin of Stereodivergence in Cooperative Asymmetric Catalysis with Simultaneous Involvement of Two Chiral Catalysts.

    Science.gov (United States)

    Bhaskararao, Bangaru; Sunoj, Raghavan B

    2015-12-23

    Accomplishing high diastereo- and enantioselectivities simultaneously is a persistent challenge in asymmetric catalysis. The use of two chiral catalysts in one-pot conditions might offer new avenues to this end. Chirality transfer from a catalyst to product gets increasingly complex due to potential chiral match-mismatch issues. The origin of high enantio- and diastereoselectivities in the reaction between a racemic aldehyde and an allyl alcohol, catalyzed by using axially chiral iridium phosphoramidites PR/S-Ir and cinchona amine is established through transition-state modeling. The multipoint contact analysis of the stereocontrolling transition state revealed how the stereodivergence could be achieved by inverting the configuration of the chiral catalysts that are involved in the activation of the reacting partners. While the enantiocontrol is identified as being decided in the generation of PR/S-Ir-π-allyl intermediate from the allyl alcohol, the diastereocontrol arises due to the differential stabilizations in the C-C bond formation transition states. The analysis of the weak interactions in the transition states responsible for chiral induction revealed that the geometric disposition of the quinoline ring at the C8 chiral carbon of cinchona-enamine plays an anchoring role. The quinolone ring is noted as participating in a π-stacking interaction with the phenyl ring of the Ir-π-allyl moiety in the case of PR with the (8R,9R)-cinchona catalyst combination, whereas a series of C-H···π interactions is identified as vital to the relative stabilization of the stereocontrolling transition states when PR is used with (8S,9S)-cinchona.

  14. Chiral THz metamaterial with tunable optical activity

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Jiangfeng [Los Alamos National Laboratory; Taylor, Antoinette [Los Alamos National Laboratory; O' Hara, John [Los Alamos National Laboratory; Chowdhury, Roy [Los Alamos National Laboratory; Zhao, Rongkuo [IOWA STATE UNIV; Soukoullis, Costas M [IOWA STATE UNIV

    2010-01-01

    Optical activity in chiral metamaterials is demonstrated in simulation and shows actively tunable giant polarization rotation at THz frequencies. Electric current distributions show that pure chirality is achieved by our bi-Iayer chiral metamaterial design. The chirality can be optically controlled by illumination with near-infrared light. Optical activity, occurring in chiral materials such as DNA, sugar and many other bio-molecules, is a phenomenon of great importance to many areas of science including molecular biology, analytical chemistry, optoelectronics and display applications. This phenomenon is well understood at an effective medium level as a magnetic/electric moment excited by the electric/magnetic field of the incident electromagnetic (EM) wave. Usually, natural chiral materials exhibit very weak optical activity e.g. a gyrotropic quartz crystal. The optical activity of chiral metamaterials, however, can be five orders of magnitude stronger. Chiral metamaterials are made of sub-wavelength resonators lacking symmetry planes. The asymmetry allows magnetic moments to be excited by the electric field of the incident EM wave and vice versa. Recently, chiral metamaterials have been demonstrated and lead to prospects in giant optical activity, circular dichroism, negative refraction and reversing the Casmir force. These fascinating optical properties require strong chirality, which may be designed through the microscopic structure of chiral metamaterials. However, these metamaterials have a fixed response function, defined by the geometric structuring, which limits their ability to manipulate EM waves. Active metamaterials realize dynamic control of response functions and have produced many influential applications such as ultra-fast switching devices, frequency and phase modulation and memory devices. Introducing active designs to chiral metamaterials will give additional freedom in controlling the optical activity, and therefore enable dynamic manipulation

  15. Cosmic chirality both true and false.

    Science.gov (United States)

    Barron, Laurence D

    2012-12-01

    The discrete symmetries of parity P, time reversal T, and charge conjugation C may be used to characterize the properties of chiral systems. It is well known that parity violation infiltrates into ordinary matter via an interaction between the nucleons and electrons, mediated by the Z(0) particle, that lifts the degeneracy of the mirror-image enantiomers of a chiral molecule. Being odd under P but even under T, this P-violating interaction exhibits true chirality and so may induce absolute enantioselection under all circumstances. It has been suggested that CP violation may also infiltrate into ordinary matter via a P-odd, T-odd interaction mediated by the (as yet undetected) axion. This CP-violating interaction exhibits false chirality and so may induce absolute enantioselection in processes far from equilibrium. Both true and false cosmic chirality should be considered together as possible sources of homochirality in the molecules of life.

  16. A liquid crystalline chirality balance for vapours

    Science.gov (United States)

    Ohzono, Takuya; Yamamoto, Takahiro; Fukuda, Jun-Ichi

    2014-04-01

    Chiral discrimination of vapours plays an important role in olfactory perception of biological systems and its realization by artificial sensors has been an intriguing challenge. Here, we report a simple method that tangibly visualizes the chirality of a diverse variety of molecules dissolved from vapours with high sensitivity, by making use of a structural change in a periodic microstructure of a nematic liquid crystal confined in open microchannels. This microstructure is accompanied by a topological line defect of a zigzag form with equal lengths of ‘zig’ and ‘zag.’ We find that a tiny amount of vapour of chiral molecules injected onto the liquid crystal induces the imbalance of ‘zig’ and ‘zag’ depending on its enantiomeric excess within a few seconds. Our liquid-crystal-based ‘chirality balance’ offers a simple, quick and versatile chirality-sensing/-screening method for gas-phase analysis (for example, for odours, environmental chemicals or drugs).

  17. Chirality on Surfaces: Modeling and Behaviour.

    Energy Technology Data Exchange (ETDEWEB)

    Paci, Irina; Szleifer, Igal; Ratner, Mark A.

    2007-09-01

    The research described in this product was performed in part in the Environmental Molecular Sciences Laboratory, a national scientific user facility sponsored by the Department of Energy's Office of Biological and Environmental Research and located at Pacific Northwest National Laboratory. Chirality has been a fascinating topic in chemistry, ever since its first observation by Biot in 1815. Its molecular basis was first understood by Pasteur in 1848. Enantiomers, identical in every way but mirror-images of each other, have similar physical properties, behave identically in chemical reactions with achiral molecules, but have very different interactions with chiral molecules. In recent decades, chirality has become an important direction in pharmaceutical research, as many drugs have stereoselective activity. This review focuses on a new aspect of chiral resolution on solid surfaces, and relationships between molecular structure, thermodynamic effects, and the result of chiral surface self-organization.

  18. Lambda Hypernuclei in a Chiral Hadronic Model

    Institute of Scientific and Technical Information of China (English)

    LIANG Yin-Hua; GUO Hua

    2005-01-01

    @@ Nuclear matter calculations in a chiral hadronic model have been performed. It has been found that the scalar and the vector potentials and binding energies per nucleon in the chiral hadronic model are very close to those of the microscopic relativistic Brueckner-Hartree-Fock calculations. The good results for finite nuclei can be obtained in the mean field approximation only if scalar mass ms and coupling constant gs have been improved with the fixed values of cs2 ≡ g2s(M/ms)2 as those given by the original parameter sets of the chiral hadronic model. Then the chiral hadronic model is extended to lambda hypernuclei. Our results predicted by the chiral hadronic model are compared with those by the nonlinear Walecka model. It has been shown that the hadronic model can also be used to describe lambda hypernuclei successfully.

  19. Chiral Superfluidity for the Heavy Ion Collisions

    CERN Document Server

    Kalaydzhyan, T

    2013-01-01

    We argue that the strongly coupled quark-gluon plasma formed at LHC and RHIC can be considered as a chiral superfluid. The "normal" component of the fluid is the thermalized matter in common sense, while the "superfluid" part consists of long wavelength (chiral) fermionic states moving independently. We use the bosonization procedure with a finite cut-off and obtain a dynamical axion-like field out of the chiral fermionic modes. Then we use relativistic hydrodynamics for macroscopic description of the effective theory obtained after the bosonization. Finally, solving the hydrodynamic equations in gradient expansion, we find that in the presence of external electromagnetic fields the motion of the "superfluid" component gives rise to the chiral magnetic, chiral electric and dipole wave effects. Latter two effects are specific for a two-component fluid, which provides us with crucial experimental tests of the model. By considering probe quarks one can show that the fermionic spectrum at the intermediate tempera...

  20. Principal chiral model on superspheres

    Energy Technology Data Exchange (ETDEWEB)

    Mitev, V.; Schomerus, V. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Quella, T. [Amsterdam Univ. (Netherlands). Inst. for Theoretical Physics

    2008-09-15

    We investigate the spectrum of the principal chiral model (PCM) on odd-dimensional superspheres as a function of the curvature radius R. For volume-filling branes on S{sup 3} {sup vertical} {sup stroke} {sup 2}, we compute the exact boundary spectrum as a function of R. The extension to higher dimensional superspheres is discussed, but not carried out in detail. Our results provide very convincing evidence in favor of the strong-weak coupling duality between supersphere PCMs and OSP(2S+2 vertical stroke 2S) Gross-Neveu models that was recently conjectured by Candu and Saleur. (orig.)

  1. Status of chiral meson physics

    Energy Technology Data Exchange (ETDEWEB)

    Bijnens, Johan [Department of Astronomy and Theoretical Physics, Lund University, Sölvegatan 14A, SE 22362 Lund (Sweden)

    2016-01-22

    This talk includes a short introduction to Chiral Perturbation Theory in the meson sector concentrating on a number of recent developments. I discuss the latest fit of the low-energy constants. Finite volume corrections are discussed for the case with twisted boundary conditions for form-factors and first results at two-loops for three flavours for masses. The last part discusses the extension to other symmetry breaking patterns relevant for technicolour and related theories as well as the calculation of leading logarithms to high loop orders.

  2. Chiral Anomaly in Contorted Spacetimes

    CERN Document Server

    Mielke, E W

    1999-01-01

    The Dirac equation in Riemann-Cartan spacetimes with torsion is reconsidered. As is well-known, only the axial covector torsion $A$, a one-form, couples to massive Dirac fields. Using diagrammatic techniques, we show that besides the familiar Riemannian term only the Pontrjagin type four-form $dA\\wedge dA$ does arise additionally in the chiral anomaly, but not the Nieh-Yan term $d ^* A$, as has been claimed recently. Implications for cosmic strings in Einstein-Cartan theory as well as for Ashtekar's canonical approach to quantum gravity are discussed.

  3. Threshold pion production in proton-proton collisions at NNLO in chiral EFT

    Science.gov (United States)

    Baru, V.; Epelbaum, E.; Filin, A. A.; Hanhart, C.; Krebs, H.; Myhrer, F.

    2016-05-01

    The reaction NN → NN π offers a good testing ground for chiral effective field theory at intermediate energies. It challenges our understanding of the first inelastic channel in nucleon-nucleon scattering and of the charge symmetry breaking pattern in hadronic reactions. In our previous studies, we presented a complete calculation of the pion production operator for s -wave pions up-to-and-including next-to-next-to-leading order (NNLO) in the formulation of chiral effective field theory, which includes pions, nucleons and Δ(1232) degrees of freedom. In this paper we calculate the near-threshold cross section for the pp → d π+ reaction by performing the convolution of the obtained operators with nuclear wave functions based on modern phenomenological and chiral potentials. The available chiral NN wave functions are constructed with a cutoff comparable with the momentum transfer scale inherent in pion production reactions. Hence, a significant portion of the dynamical intermediate-range physics is thereby cut off by them. On the other hand, the NNLO amplitudes evaluated with phenomenological wave functions appear to be largely independent of the NN model used and give corrections to the dominant leading-order contributions as expected from dimensional analysis. The result gives support to the counting scheme used to classify the pion production operators, which is a precondition for a reliable investigation of the chirally suppressed neutral pion production. The explicit inclusion of the Δ(1232) is found to be important but smaller than expected due to cancellations.

  4. A strategy for tuning achiral main-chain polymers into helical assemblies and chiral memory systems.

    Science.gov (United States)

    Yang, Dong; Zhao, Yin; Lv, Kai; Wang, Xiufeng; Zhang, Wei; Zhang, Li; Liu, Minghua

    2016-01-28

    A general strategy to tune the achiral main chain polymers into helical nanoassemblies was proposed based on the co-gelation approach. As an example, two achiral main chain polymers, PCz8 and PSi8, were selected, and their co-assembly with an amphiphilic l- or d-glutamide gelator was investigated. Although the polymers could not form gels individually, they could form co-gels with the gelator and the resultant gels exhibited macroscopic supramolecular chirality, which could be confirmed by CD spectra and SEM observations. Moreover, the supramolecular chirality can be memorized even after the gelator molecules were removed. Remarkably, either the gelator-containing or gelator-free chiral polymer assemblies showed circularly polarized luminescence (CPL), which is usually inherent to intrinsic chiral polymers. It was suggested that during the co-gelation, the chirality of the gelator was transferred to and memorized by the achiral polymers. The approach seems to be general and we provided the first example to tune the achiral polymers into helical assemblies through the co-gelation.

  5. Light meson electromagnetic form factors from three-flavor lattice QCD with exact chiral symmetry

    CERN Document Server

    Aoki, S; Feng, X; Hashimoto, S; Kaneko, T; Noaki, J; Onogi, T

    2015-01-01

    We study the chiral behavior of the electromagnetic (EM) form factors of pion and kaon in three-flavor lattice QCD. In order to make a direct comparison of the lattice data with chiral perturbation theory (ChPT), we employ the overlap quark action that has exact chiral symmetry. Gauge ensembles are generated at a lattice spacing of 0.11 fm with four pion masses ranging between M_pi \\simeq 290 MeV and 540 MeV and with a strange quark mass m_s close to its physical value. We utilize the all-to-all quark propagator technique to calculate the EM form factors with high precision. Their dependence on m_s and on the momentum transfer is studied by using the reweighting technique and the twisted boundary conditions for the quark fields, respectively. A detailed comparison with SU(2) and SU(3) ChPT reveals that the next-to-next-to-leading order terms in the chiral expansion are important to describe the chiral behavior of the form factors in the pion mass range studied in this work. We estimate the relevant low-energy...

  6. Spin-flavor structure of chiral-odd GPDs in the large-N_c limit

    CERN Document Server

    Schweitzer, P

    2016-01-01

    We study the spin-flavor structure of the nucleon's chiral-odd generalized parton distributions (transversity GPDs) in the large-N_c limit of QCD. In contrast to the chiral-even case, only three combinations of the four chiral-odd GPDs are non-zero in the leading order of the 1/N_c expansion: E_T-bar = E_T + 2 H_T-tilde, H_T and E_T-tilde. The degeneracy is explained by the absence of spin-orbit interactions correlating the transverse momentum transfer with the transverse quark spin. It can also be deduced from the natural N_c-scaling of the quark-nucleon helicity amplitudes associated with the GPDs. In the GPD E_T-bar the flavor-singlet component u + d is leading in the 1/N_c expansion, while in H_T and E_T-tilde it is the flavor-nonsinglet components u - d. The large-N_c relations are consistent with the spin-flavor structure extracted from hard exclusive pi0 and eta electroproduction data, if it is assumed that the processes are mediated by twist-3 amplitudes involving the chiral-odd GPDs and the chiral-od...

  7. Light meson electromagnetic form factors from three-flavor lattice QCD with exact chiral symmetry

    Science.gov (United States)

    Aoki, S.; Cossu, G.; Feng, X.; Hashimoto, S.; Kaneko, T.; Noaki, J.; Onogi, T.

    2016-02-01

    We study the chiral behavior of the electromagnetic (EM) form factors of pions and kaons in three-flavor lattice QCD. In order to make a direct comparison of the lattice data with chiral perturbation theory (ChPT), we employ the overlap quark action that has exact chiral symmetry. Gauge ensembles are generated at a lattice spacing of 0.11 fm with four pion masses ranging between Mπ≃290 MeV and 540 MeV and with a strange quark mass ms close to its physical value. We utilize the all-to-all quark propagator technique to calculate the EM form factors with high precision. Their dependence on ms and on the momentum transfer is studied by using the reweighting technique and the twisted boundary conditions for the quark fields, respectively. A detailed comparison with SU(2) and SU(3) ChPT reveals that the next-to-next-to-leading order terms in the chiral expansion are important to describe the chiral behavior of the form factors in the pion mass range studied in this work. We estimate the relevant low-energy constants and the charge radii, and find reasonable agreement with phenomenological and experimental results.

  8. New possibilities for the gauging of chiral bosons

    CERN Document Server

    Abreu, Everton M C; Wotzasek, C; Abreu, Everton M. C.; Dutra, Alvaro de Souza; Wotzasek, Clovis

    2003-01-01

    We study a new mechanism for the electromagnetic gauging of chiral bosons showing that new possibilities emerge for the interacting theory of chiral scalars. We introduce a chirally coupled gauge field necessary to mod out the degree of freedom that obstructs gauge invariance in a system of two opposite chiral bosons soldering them together.

  9. Synthesis and characterization of mixed ligand chiral nanoclusters

    KAUST Repository

    Guven, Zekiye P.

    2016-06-22

    Chiral mixed ligand silver nanoclusters were synthesized in the presence of a chiral and an achiral ligand. While the chiral ligand led mostly to the formation of nanoparticles, the presence of the achiral ligand drastically increased the yield of nanoclusters with enhanced chiral properties. © 2016 The Royal Society of Chemistry.

  10. Chiral Ionic Liquids in Chromatographic Separation and Spectroscopic Discrimination

    Science.gov (United States)

    Li, Min; Bwambok, David K.; Fakayode, Sayo O.; Warner, Isiah M.

    Chiral ionic liquids (CILs) are a subclass of ionic liquids (ILs) in which the cation, anion, or both may be chiral. The chirality can be central, axial, or planar. CILs possess a number of unique advantageous properties which are inherited from ionic liquids including negligible vapor pressure, wide liquidus temperature range, high thermal stability, and high tunability. Due to their dual functionalities as chiral selectors and chiral solvents simultaneously, CILs recently have been widely used both in enantiomeric chromatographic separation and in chiral spectroscopic discrimination. In this chapter, the various applications of CILs in chiral chromatographic separations such as GC, HPLC, CE, and MEKC are reviewed. The applications of CILs in enantiomeric spectroscopic discrimination using techniques such as NMR, fluorescence, and NIR are described. In addition, chiral recognition and separation mechanism using the CILs as chiral selectors or chiral solvents is also discussed.

  11. Chlorophylls, Symmetry, Chirality, and Photosynthesis

    Directory of Open Access Journals (Sweden)

    Mathias O. Senge

    2014-09-01

    Full Text Available Chlorophylls are a fundamental class of tetrapyrroles and function as the central reaction center, accessory and photoprotective pigments in photosynthesis. Their unique individual photochemical properties are a consequence of the tetrapyrrole macrocycle, the structural chemistry and coordination behavior of the phytochlorin system, and specific substituent pattern. They achieve their full potential in solar energy conversion by working in concert in highly complex, supramolecular structures such as the reaction centers and light-harvesting complexes of photobiology. The biochemical function of these structures depends on the controlled interplay of structural and functional principles of the apoprotein and pigment cofactors. Chlorophylls and bacteriochlorophylls are optically active molecules with several chiral centers, which are necessary for their natural biological function and the assembly of their supramolecular complexes. However, in many cases the exact role of chromophore stereochemistry in the biological context is unknown. This review gives an overview of chlorophyll research in terms of basic function, biosynthesis and their functional and structural role in photosynthesis. It highlights aspects of chirality and symmetry of chlorophylls to elicit further interest in their role in nature.

  12. Chiral transition with magnetic fields

    CERN Document Server

    Ayala, Alejandro; Mizher, Ana Julia; Rojas, Juan Cristobal; Villavicencio, Cristian

    2014-01-01

    We study the nature of the chiral transition for an effective theory with spontaneous breaking of symmetry, where charged bosons and fermions are subject to the effects of a constant external magnetic field. The problem is studied in terms of the relative intensity of the magnetic field with respect to the mass and the temperature. When the former is the smallest of the scales, we present a suitable method to obtain magnetic and thermal corrections up to ring order at high temperature. By these means, we solve the problem of the instability in the boson sector for these theories, where the squared masses, taken as functions of the order parameter, can vanish and even become negative. The solution is found by considering the screening properties of the plasma, encoded in the resummation of the ring diagrams at high temperature. We also study the case where the magnetic field is the intermediate of the three scales and explore the nature of the chiral transition as we vary the field strength, the coupling const...

  13. Nucleic acids, proteins, and chirality

    Science.gov (United States)

    Usher, D. A.; Profy, A. T.; Walstrum, S. A.; Needels, M. C.; Bulack, S. C.; Lo, K. M.

    1984-01-01

    The present investigation is concerned with experimental results related, in one case, to the chirality of nucleotides, and, in another case, to the possibility of a link between the chirality of nucleic acids, and that of peptides. It has been found that aminoacylation of the 'internal' hydroxyl group of a dinucleoside monophosphate can occur stereoselectively. However, this reaction has not yet been made a part of a working peptide synthesis scheme. The formation and cleavage of oligonucleotides is considered. In the event of the formation of a helical complex between the oligonucleotide and the polymer, 1-prime,5-prime-bonds in the oligomer are found to become more resistant towards cleavage. The conditions required for peptide bond formation are examined, taking into account the known structures of RNA and possible mechanisms for prebiotic peptide bond formation. The possibility is considered that the 2-prime,5-prime-internucleotide linkage could have played an important part in the early days of biological peptide synthesis.

  14. Chiral differential operators and topology

    CERN Document Server

    Cheung, Pokman

    2010-01-01

    The first part of this paper provides a new formulation of chiral differential operators (CDOs) in terms of global geometric quantities. The main result is a recipe to define essentially all sheaves of smooth CDOs on a cs-manifold; its ingredients consist of an affine connection and an even 3-form that trivializes the first Pontrjagin form. With the connection fixed, two suitable 3-forms define isomorphic sheaves of CDOs if and only if their difference is exact. Moreover, conformal structures are in one-to-one correspondence with even 1-forms that trivialize the first Chern form. The second part of this paper concerns the construction of what may be called "chiral Dolbeault complexes". The classical Dolbeault complex of a complex manifold M may be viewed as the functions on an associated cs-manifold with the action of an odd vector field Q that satisfies Q^2=0. Motivated by this, we study the condition under which a conformal sheaf of CDOs on that cs-manifold admits an odd derivation Q' that extends Q and sat...

  15. Nuclear chiral dynamics and thermodynamics

    CERN Document Server

    Holt, J W; Weise, W

    2013-01-01

    This presentation reviews an approach to nuclear many-body systems based on the spontaneously broken chiral symmetry of low-energy QCD. In the low-energy limit, for energies and momenta small compared to a characteristic symmetry breaking scale of order 1 GeV, QCD is realized as an effective field theory of Goldstone bosons (pions) coupled to heavy fermionic sources (nucleons). Nuclear forces at long and intermediate distance scales result from a systematic hierarchy of one- and two-pion exchange processes in combination with Pauli blocking effects in the nuclear medium. Short distance dynamics, not resolved at the wavelengths corresponding to typical nuclear Fermi momenta, are introduced as contact interactions between nucleons. Apart from a set of low-energy constants associated with these contact terms, the parameters of this theory are entirely determined by pion properties and low-energy pion-nucleon scattering observables. This framework (in-medium chiral perturbation theory) can provide a realistic des...

  16. Spontaneous Planar Chiral Symmetry Breaking in Cells

    Science.gov (United States)

    Hadidjojo, Jeremy; Lubensky, David

    Recent progress in animal development has highlighted the central role played by planar cell polarity (PCP) in epithelial tissue morphogenesis. Through PCP, cells have the ability to collectively polarize in the plane of the epithelium by localizing morphogenetic proteins along a certain axis. This allows direction-dependent modulation of tissue mechanical properties that can translate into the formation of complex, non-rotationally invariant shapes. Recent experimental observations[1] show that cells, in addition to being planar-polarized, can also spontaneously develop planar chirality, perhaps in the effort of making yet more complex shapes that are reflection non-invariant. In this talk we will present our work in characterizing general mechanisms that can lead to spontaneous chiral symmetry breaking in cells. We decompose interfacial concentration of polarity proteins in a hexagonal cell packing into irreducible representations. We find that in the case of polar concentration distributions, a chiral state can only be reached from a secondary instability after the cells are polarized. However in the case of nematic distributions, we show that a finite-amplitude (subcritical, or ``first-order'') nematic transition can send the system from disorder directly to a chiral state. In addition, we find that perturbing the system by stretching the hexagonal packing enables direct (supercritical, or ``second-order'') chiral transition in the nematic case. Finally, we do a Landau expansion to study competition between stretch-induced chirality and the tendency towards a non-chiral state in packings that have retained the full 6-fold symmetry.

  17. New Chiral Calixarene Derivatives: Syntheses and Their Chiral Recognition Toward Amino Acids by UV-Vis Spectroscopy

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Three novel types of chiral calixarene derivatives 5, 8, and 10 were designed and synthesized by introducing chiral units to parent calixarenes. Their chiralities were confirmed by rotational analysis. Chiral recognition properties of these host compounds towards L- and D-threonine were studied by UV-Vis spectroscopy. The results indicated that calixarene derivatives 5 and 8 exhibited good chiral recognition capabilities toward L- or D-threonine. Although calixarene derivative 10 had no evident chiral recognition ability, the supramolecules of calixarene derivative 10 with L- or D-threonine showed a hypochromic effect or hyperchromic effect respectively. Therefore, calixarene derivative 10 might serve as a good chiral UV-indicator.

  18. Biocatalysis: synthesis of chiral intermediates for drugs.

    Science.gov (United States)

    Patel, Ramesh N

    2006-11-01

    Chirality is a key factor in the safety and efficacy of many drug products and thus the production of single enantiomers of drug intermediates has become increasingly important in the pharmaceutical industry. Chiral intermediates and fine chemicals are in high demand for the bulk preparation of drug substances and agricultural products. There has been an increasing awareness of the enormous potential of the use of microorganisms and microorganism-derived enzymes for the transformation of synthetic chemicals with high chemo-, regio- and enantioselectivities. In this article, biocatalytic processes are described for the synthesis of chiral intermediates for drugs.

  19. Interplay between Deconfinement and Chiral Properties

    CERN Document Server

    Suganuma, Hideo; Redlich, Krzysztof; Sasaki, Chihiro

    2016-01-01

    We study interplay between confinement/deconfinement and chiral properties. We derive some analytical relations of the Dirac modes with the confinement quantities, such as the Polyakov loop, its susceptibility and the string tension. For the confinement quantities, the low-lying Dirac eigenmodes are found to give negligible contribution, while they are essential for chiral symmetry breaking. This indicates no direct, one-to-one correspondence between confinement/deconfinement and chiral properties in QCD. We also investigate the Polyakov loop in terms of the eigenmodes of the Wilson, the clover and the domain-wall fermion kernels, respectively.

  20. Enhanced Chiral Recognition by Cyclodextrin Dimers

    Directory of Open Access Journals (Sweden)

    Bart Jan Ravoo

    2011-07-01

    Full Text Available In this article we investigate the effect of multivalency in chiral recognition. To this end, we measured the host-guest interaction of a β-cyclodextrin dimer with divalent chiral guests. We report the synthesis of carbohydrate-based water soluble chiral guests functionalized with two borneol, menthol, or isopinocampheol units in either (+ or (– configuration. We determined the interaction of these divalent guests with a β-cyclodextrin dimer using isothermal titration calorimetry. It was found that—in spite of a highly unfavorable conformation—the cyclodextrin dimer binds to guest dimers with an increased enantioselectivity, which clearly reflects the effect of multivalency.

  1. Synthesis of chiral dopants based on carbohydrates.

    Science.gov (United States)

    Tsuruta, Toru; Koyama, Tetsuo; Yasutake, Mikio; Hatano, Ken; Matsuoka, Koji

    2014-07-01

    Chiral dopants based on carbohydrates for nematic liquid crystals were synthesized from D-glucose, and their helical twisting power (HTP) values were evaluated. The chiral dopants induced helices in the host nematic liquid crystals. An acetyl derivative having an ether-type glycosidic linkage between carbohydrate and a mesogenic moiety showed the highest HTP value of 10.4 μm(-1), while an acetyl derivative having an anomeric ester-type linkage did not show any HTP. It was surprising that this molecule had no HTP despite the presence of chirality in the molecule. A relationship between HTP and specific rotation was not observed in this study.

  2. Critical Temperature of Chiral Symmetry Restoration for Quark Matter with a Chiral Chemical Potential

    CERN Document Server

    Ruggieri, M

    2016-01-01

    In this article we study restoration of chiral symmetry at finite temperature for quark matter with a chiral chemical potential, $\\mu_5$, by means of a quark-meson model with vacuum fluctuations included. Vacuum fluctuations give a divergent contribution to the vacuum energy, so the latter has to be renormalized before computing physical quantities. The vacuum term is important for restoration of chiral symmetry at finite temperature and $\\mu_5\

  3. Role of keto–enol tautomerization in a chiral phosphoric acid catalyzed asymmetric thiocarboxylysis of meso-epoxide: a DFT study

    KAUST Repository

    Ajitha, Manjaly John

    2015-09-15

    The mechanism of a chiral phosphoric acid catalyzed thiocarboxylysis of meso-epoxide was investigated by density functional theory (DFT) calculations (M06-2X). The nucleophilic ring opening of epoxide by thiobenzoic acid was found to proceed via a concerted termolecular transition state with a simultaneous dual proton transfer to yield the β-hydroxy thioester product. Electrostatic interactions together with the steric environment inside the chiral catalyst play an important role in determining the enantioselectivity of the reaction.

  4. Binary mixtures of chiral gases

    CERN Document Server

    Presilla, Carlo

    2015-01-01

    A possible solution of the well known paradox of chiral molecules is based on the idea of spontaneous symmetry breaking. At low pressure the molecules are delocalized between the two minima of a given molecular potential while at higher pressure they become localized in one minimum due to the intermolecular dipole-dipole interactions. Evidence for such a phase transition is provided by measurements of the inversion spectrum of ammonia and deuterated ammonia at different pressures. In particular, at pressure greater than a critical value no inversion line is observed. These data are well accounted for by a model previously developed and recently extended to mixtures. In the present paper, we discuss the variation of the critical pressure in binary mixtures as a function of the fractions of the constituents.

  5. Chiral exceptional points in metasurfaces

    Science.gov (United States)

    Kang, Ming; Chen, Jing; Chong, Y. D.

    2016-09-01

    An exceptional point (EP) is a degeneracy occurring in a non-energy-conserving system, in which two eigenvectors of a non-Hermitian Hamiltonian coalesce. We explore how EPs can be realized in a metamaterial surface, or metasurface, consisting of a pair of lossy coupled linear antennas in each unit cell. EPs appear in the eigenvectors of the transmission matrix by tuning the frequency and the coupling and loss rates of the metasurface. Each EP is associated with the appearance of a circularly polarized transmission eigenstate; hence, within the parameter space of the system, the EPs lie along pairs of curves with distinct chirality. Our results are obtained using finite-difference time-domain simulations, as well as a fitted coupled-mode theory. The coupled-mode theory agrees well with the numerical results and is capable of accurately predicting the EP f curves.

  6. Resolution of the Chiral Drugs

    Institute of Scientific and Technical Information of China (English)

    DENG; JinGen

    2001-01-01

    Chiral drugs are generally not permitted to be used in racemic form so that unintended side effects and unnecessary environmental hazards are avoided. Moreover, homochiral molecules are required immediately to progress key toxicological and clinical studies in the drug discovery. One series of technologies which can rapidly supply homochiral compounds is the separation of racemates, and of those the technique of crystallization of diastereomers is extremely effective-principally because it is simple to operate and it affords both enantiomers. In classical resolution via diastereoisomeric salt formation, the resolved compounds are limited to a given racemic acid or base and the choice of a suitable resolving agent for a racemic target compound is achieved by time-consuming trial-and-error procedure.  ……

  7. Resolution of the Chiral Drugs

    Institute of Scientific and Technical Information of China (English)

    DENG JinGen; ZHU Jin

    2001-01-01

    @@ Chiral drugs are generally not permitted to be used in racemic form so that unintended side effects and unnecessary environmental hazards are avoided. Moreover, homochiral molecules are required immediately to progress key toxicological and clinical studies in the drug discovery. One series of technologies which can rapidly supply homochiral compounds is the separation of racemates, and of those the technique of crystallization of diastereomers is extremely effective-principally because it is simple to operate and it affords both enantiomers. In classical resolution via diastereoisomeric salt formation, the resolved compounds are limited to a given racemic acid or base and the choice of a suitable resolving agent for a racemic target compound is achieved by time-consuming trial-and-error procedure.

  8. Chiral Magnetic Effect in Heavy Ion Collisions

    CERN Document Server

    Liao, Jinfeng

    2016-01-01

    The Chiral Magnetic Effect (CME) is a remarkable phenomenon that stems from highly nontrivial interplay of QCD chiral symmetry, axial anomaly, and gluonic topology. It is of fundamental importance to search for the CME in experiments. The heavy ion collisions provide a unique environment where a hot chiral-symmetric quark-gluon plasma is created, gluonic topological fluctuations generate chirality imbalance, and very strong magnetic fields $|\\vec{\\bf B}|\\sim m_\\pi^2$ are present during the early stage of such collisions. Significant efforts have been made to look for CME signals in heavy ion collision experiments. In this contribution we give a brief overview on the status of such efforts.

  9. Development of safer molecules through chirality

    Directory of Open Access Journals (Sweden)

    Patil P

    2006-10-01

    Full Text Available Many of the drugs currently used in medical practice are mixtures of enantiomers (racemates. Many a times, the two enantiomers differ in their pharmacokinetic and pharmacodynamic properties. Replacing existing racemates with single isomers has resulted in improved safety and/or efficacy profile of various racemates. In this review, pharmacokinetic and pharmacodynamic implications of chirality are discussed in brief, followed by an overview of some important chiral switches that have yielded safer alternatives. These include levosalbutamol, S-ketamine, levobupivacaine, S-zopiclone, levocetirizine, S-amlodipine, S-atenolol, S-metoprolol, S-omeprazole, S-pantoprazole and R-ondansetron. Few potential chiral switches under evaluation and some chiral switches that have not been successful are also discussed.

  10. Random matrix model approach to chiral symmetry

    CERN Document Server

    Verbaarschot, J J M

    1996-01-01

    We review the application of random matrix theory (RMT) to chiral symmetry in QCD. Starting from the general philosophy of RMT we introduce a chiral random matrix model with the global symmetries of QCD. Exact results are obtained for universal properties of the Dirac spectrum: i) finite volume corrections to valence quark mass dependence of the chiral condensate, and ii) microscopic fluctuations of Dirac spectra. Comparisons with lattice QCD simulations are made. Most notably, the variance of the number of levels in an interval containing $n$ levels on average is suppressed by a factor $(\\log n)/\\pi^2 n$. An extension of the random matrix model model to nonzero temperatures and chemical potential provides us with a schematic model of the chiral phase transition. In particular, this elucidates the nature of the quenched approximation at nonzero chemical potential.

  11. Chiral dynamics with (non)strange quarks

    Science.gov (United States)

    Kubis, Bastian; Meißner, Ulf-G.

    2017-01-01

    We review the results and achievements of the project B.3. Topics addressed include pion photoproduction off the proton and off deuterium, three-flavor chiral perturbation theory studies, chiral symmetry tests in Goldstone boson decays, the development of unitarized chiral perturbation theory to next-to-leading order, the two-pole structure of the Λ(1405), the dynamical generation of the lowest S11 resonances, the theory of hadronic atoms and its application to various systems, precision studies in light-meson decays based on dispersion theory, the Roy-Steiner analysis of pion-nucleon scattering, a high-precision extraction of the elusive pion-nucleon σ-term, and aspects of chiral dynamics in few-nucleon systems.

  12. Chiral susceptibility and the scalar Ward identity.

    Energy Technology Data Exchange (ETDEWEB)

    Chang, L.; Liu, Y.-X.; Roberts, C. D.; Shi, Y.-M.; Sun, W.-M.; Zong, H.-S.; Physics; Inst. of Applied Physics and Computational Mathematics; Peking Univ.; National Lab. of Heavy Ion Accelerator; Univ. of New South Wales; Nanjing Univ.; Joint Center for Particle, Nuclear Physics and Cosmology

    2009-03-01

    The chiral susceptibility is given by the scalar vacuum polarization at zero total momentum. This follows directly from the expression for the vacuum quark condensate so long as a nonperturbative symmetry preserving truncation scheme is employed. For QCD in-vacuum the susceptibility can rigorously be defined via a Pauli-Villars regularization procedure. Owing to the scalar Ward identity, irrespective of the form or Ansatz for the kernel of the gap equation, the consistent scalar vertex at zero total momentum can automatically be obtained and hence the consistent susceptibility. This enables calculation of the chiral susceptibility for markedly different vertex Ansaetze. For the two cases considered, the results were consistent and the minor quantitative differences easily understood. The susceptibility can be used to demarcate the domain of coupling strength within a theory upon which chiral symmetry is dynamically broken. Degenerate massless scalar and pseudoscalar bound-states appear at the critical coupling for dynamical chiral symmetry breaking.

  13. New Advances in Chiral Catalyst Immobilization

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ Asymmetric catalysis of organic reactions is one of the most efficient ways to obtain optically pure chiral compounds, which are crucially important to the development of modern pharmaceutical and fine chemical industries, as well as material science.

  14. Notes on conservation laws in chiral hydrodynamics

    CERN Document Server

    Zakharov, V I

    2016-01-01

    We consider chiral fluids within the standard framework of a chiral-invariant underlying field theory, anomalous in presence of electromagnetic fields. Apart from the Noether axial current of the underlying theory, in the limit of ideal fluid there exist extra conserved currents, corresponding to classical helical motions. The extra conservation laws are known to break down once viscosity is non-vanishing. Which looks puzzling, as if introduction of viscosity were inconsistent with chiral invariance. As a resolution of the puzzle, we argue that locally one can introduce an inertial frame where an extra conservation law still holds. In other words, the extra currents are covariantly conserved. The emergent gravitational field is determined by dynamics of the viscous fluid. We turn then to instabilities of chiral plasma against decays into helical magnetic or vortical configurations. We emphasise similarity between the two cases in the far infrared region, responsible for the decays. This similarity is not appa...

  15. Application of cyclodextrins in chiral capillary electrophoresis.

    Science.gov (United States)

    Rezanka, Pavel; Navrátilová, Klára; Rezanka, Michal; Král, Vladimír; Sýkora, David

    2014-10-01

    CE represents a very powerful separation tool in the area of chiral separations. CD-mediated chiral CE is a continuously flourishing technique within the frame of the electromigration methods. In this review, a brief overview of the synthetic procedures leading to modified CDs is provided first. Next, selected aspects related to the utilization of CDs in chiral CE are discussed specifically in the view of recently published data. Advantages of CDs and basic principles of chiral CE are remained. The topic of the determination of binding constants is touched. Particular attention is paid to the effort aiming at better understanding of the molecular level of the enantiorecognition between CDs and the analyte in the solution. Powerful approaches extensively utilized in this field are NMR, molecular modeling, and computer simulations. Then, a summary of applications of CDs in the CE enantioseparations is given, covering years 2008-2013. Finally, the general trend of modified CDs use in separation science is statistically evaluated.

  16. Chiral transition of fundamental and adjoint quarks

    Energy Technology Data Exchange (ETDEWEB)

    Capdevilla, R.M. [Instituto de Física Teórica, UNESP – Universidade Estadual Paulista, Rua Dr. Bento T. Ferraz, 271, Bloco II, 01140-070 São Paulo, SP (Brazil); Doff, A., E-mail: agomes@utfpr.edu.br [Universidade Tecnológica Federal do Paraná – UTFPR – DAFIS, Av. Monteiro Lobato Km 04, 84016-210 Ponta Grossa, PR (Brazil); Natale, A.A., E-mail: natale@ift.unesp.br [Instituto de Física Teórica, UNESP – Universidade Estadual Paulista, Rua Dr. Bento T. Ferraz, 271, Bloco II, 01140-070 São Paulo, SP (Brazil); Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, 09210-170 Santo André, SP (Brazil)

    2014-01-20

    The chiral symmetry breaking transition of quarks in the fundamental and adjoint representation is studied in a model where the gap equation contains two contributions, one containing a confining propagator and another corresponding to the exchange of one-dressed dynamically massive gluons. When quarks are in the fundamental representation the confinement effect dominates the chiral symmetry breaking while the gluon exchange is suppressed due to the dynamical gluon mass effect in the propagator and in the coupling constant. In this case the chiral and deconfinement transition temperatures are approximately the same. For quarks in the adjoint representation, due to the larger Casimir eigenvalue, the gluon exchange is operative and the chiral transition happens at a larger temperature than the deconfinement one.

  17. NN Interaction in Chiral Constituent Quark Models

    CERN Document Server

    Valcarce, A; González, P

    2003-01-01

    We review the actual state in the description of the NN interaction by means of chiral constituent quark models. We present a series of relevant features that are nicely explained within the quark model framework.

  18. Large Enhancement of Circular Dichroism Using an Embossed Chiral Metamaterial

    CERN Document Server

    Mousavi, S Hamed Shams; El-Sayed, Mostafa A; Eftekhar, Ali A; Adibi, Ali

    2016-01-01

    In the close vicinity of a chiral nanostructure, the circular dichroism of a biomolecule could be greatly enhanced, due to the interaction with the local superchiral fields. Modest enhancement of optical activity using a planar metamaterial, with some chiral properties, and achiral nanoparticles has been previously reported. A more substantial chirality enhancement can be achieved in the local filed of a chiral nanostructure with a three-dimensional arrangement. Using an embossed chiral nanostructure designed for chiroptical sensing, we measure the circular dichroism spectra of two biomolecules, Chlorophylls A and B, at the molecular level, using a simple polarization resolved reflection measurement. This experiment is the first realization of the on-resonance surface-enhanced circular dichroism, achieved by matching the chiral resonances of a strongly chiral metamaterial with that of a chiral molecule, resulting in an unprecedentedly large differential CD spectrum from a monolayer of a chiral material.

  19. Bringing chiral optical forces to dominance with optical nanofibers

    CERN Document Server

    Alizadeh, M H

    2016-01-01

    Transverse spin angular momentum (SAM) of light and associated transverse chiral optical forces have received tremendous attention recently as the latter may lead to an optical separation of chiral biomolecules. Previous schemes to generate chiral forces are plagued by the fact that the chiral optical forces are orders of magnitude smaller than conventional gradient and scattering forces. The relative magnitude of chiral and non-chiral forces represents a fundamental challenge for the implementation of chiral separation schemes. In this work we demonstrate that, by spatially separating the maxima of transverse spin density from the gradient of field intensity, in the vicinity of optical nanofibers and nanowires, chiral optical forces can emerge that are stronger than gradient and scattering forces. This finding has important implications for the design of improved optical separation schemes for chiral biomolecules.

  20. On the covariantization of the chiral constraints

    CERN Document Server

    Neves, C; Wotzasek, C; Neves, C; de Abreu, E M C; Wotzasek, C

    1995-01-01

    We show that a complete covariantization of the chiral constraint in the Floreanini-Jackiw necessitates an infinite number of auxiliary Wess-Zumino fields otherwise the covariantization is only partial and unable to remove the nonlocality in the chiral boson operator. We comment on recent works that claim to obtain covariantization through the use of Batalin-Fradkin-Tyutin method, that uses just one Wess-Zumino field.

  1. Development of safer molecules through chirality

    OpenAIRE

    Patil P; Kothekar M

    2006-01-01

    Many of the drugs currently used in medical practice are mixtures of enantiomers (racemates). Many a times, the two enantiomers differ in their pharmacokinetic and pharmacodynamic properties. Replacing existing racemates with single isomers has resulted in improved safety and/or efficacy profile of various racemates. In this review, pharmacokinetic and pharmacodynamic implications of chirality are discussed in brief, followed by an overview of some important chiral switches that have yielded ...

  2. A liquid crystalline chirality balance for vapours

    OpenAIRE

    Ohzono, Takuya; Yamamoto, Takahiro; Fukuda, Jun-Ichi

    2014-01-01

    Chiral discrimination of vapours plays an important role in olfactory perception of biological systems and its realization by artificial sensors has been an intriguing challenge. Here, we report a simple method that tangibly visualizes the chirality of a diverse variety of molecules dissolved from vapours with high sensitivity, by making use of a structural change in a periodic microstructure of a nematic liquid crystal confined in open microchannels. This microstructure is accompanied by a t...

  3. Lattice quantum chromodynamics with approximately chiral fermions

    Energy Technology Data Exchange (ETDEWEB)

    Hierl, Dieter

    2008-05-15

    In this work we present Lattice QCD results obtained by approximately chiral fermions. We use the CI fermions in the quenched approximation to investigate the excited baryon spectrum and to search for the {theta}{sup +} pentaquark on the lattice. Furthermore we developed an algorithm for dynamical simulations using the FP action. Using FP fermions we calculate some LECs of chiral perturbation theory applying the epsilon expansion. (orig.)

  4. Open Problems in Understanding the Nuclear Chirality

    CERN Document Server

    Meng, Jie

    2010-01-01

    Open problems in the interpretation of the observed pair of near degenerate $\\Delta I = 1$ bands with the same parity as the chiral doublet bands are discussed. The ambiguities for the existing fingerprints of the chirality in atomic nuclei and problems in existing theory are discussed, including the description of quantum tunneling in the mean field approximation as well as the deformation, core polarization and configuration of particle rotor model (PRM). Future developments of the theoretical approach are prospected.

  5. Insights on some chiral smectic phases

    Indian Academy of Sciences (India)

    B Pansu

    2003-08-01

    Combining layered positional order as smectic order and chirality can generate complex architectures since twist parallel to the layers is not allowed. This paper will review some new experimental results on different phases resulting from the competition between smectic positional order and twist orientational order. It concerns the TGBA and the NL*, that is the liquid line phase as well as the SmQ phase. Chiral effects in the isotropic phase will also be discussed.

  6. The Chiral Dipolar Hard Sphere Model.

    OpenAIRE

    Mazars, Martial

    2009-01-01

    Abstract A simple molecular model of chiral molecules is presented in this paper : the chiral dipolar hard sphere model. The discriminatory interaction between enantiomers is represented by electrostatic (or magnetic) dipoles-dipoles interactions : short ranged steric repulsion are represented by hard sphere potential and, in each molecule, two point dipoles are located inside the sphere. The model is described in detail and some of its elementary properties are given ; in particul...

  7. Chiral symmetry and lattice gauge theory

    CERN Document Server

    Creutz, M

    1994-01-01

    I review the problem of formulating chiral symmetry in lattice gauge theory. I discuss recent approaches involving an infinite tower of additional heavy states to absorb Fermion doublers. For hadronic physics this provides a natural scheme for taking quark masses to zero without requiring a precise tuning of parameters. A mirror Fermion variation provides a possible way of extending the picture to chirally coupled light Fermions. Talk presented at "Quark Confinement and the Hadron Spectrum," Como, Italy, 20-24 June 1994.

  8. Chiral symmetry and the constituent quark model

    CERN Document Server

    Glozman, L Ya

    1995-01-01

    New results on baryon structure and spectrum developed in collaboration with Dan Riska [1-4] are reported. The main idea is that beyond the chiral symmetry spontaneous breaking scale light and strange baryons should be considered as systems of three constituent quarks with an effective confining interaction and a chiral interaction that is mediated by the octet of Goldstone bosons (pseudoscalar mesons) between the constituent quarks.

  9. Baryons in chiral constituent quark model

    CERN Document Server

    Glozman, L Ya

    1996-01-01

    Beyond the spontaneous chiral symmetry breaking scale light and strange baryons should be considered as systems of three constituent quarks with an effective confining interaction and a flavor-spin chiral interaction that is mediated by the octet of Goldstone bosons (pseudoscalar mesons) between the constituent quarks. One cannot exclude, however, the possibility that this flavor-spin interaction has an appreciable vector- and higher meson exchange component.

  10. Resonant mixing of optical orbital and spin angular momentum by using chiral silicon nanosphere clusters.

    Science.gov (United States)

    Al-Jarro, Ahmed; Biris, Claudiu G; Panoiu, Nicolae C

    2016-04-01

    We present an in-depth analysis of the resonant intermixing between optical orbital and spin angular momentum of Laguerre-Gaussian (LG) beams, mediated by chiral clusters made of silicon nanospheres. In particular, we establish a relationship between the spin and orbital quantum numbers characterizing the LG beam and the order q of the rotation symmetry group q of the cluster of nanospheres for which resonantly enhanced coupling between the two components of the optical angular momentum is observed. Thus, similar to the case of diffraction grating-mediated transfer of linear momentum between optical beams, we demonstrate that clusters of nanospheres that are invariant to specific rotation transformations can efficiently transfer optical angular momentum between LG beams with different quantum numbers. We also discuss the conditions in which the resonant interaction between LG beams and a chiral cluster of nanospheres leads to the generation of superchiral light.

  11. A Molecular Model for Chiral Symmetry Breaking

    Science.gov (United States)

    Latinwo, Folarin; Stillinger, Frank; Debenedetti, Pablo

    In this work, we present a new class of molecular models for chiral phenomena in condensed matter systems. A key feature of these models is the ability of the four-site (tetramer) ``molecules'' to inter-convert between two distinct chiral forms (enantiomers). Given this feature, we use analytical theory and computer simulations to investigate the emergent chiral properties (including symmetry breaking) over a range of conditions. In particular, we consider the single-molecule level and condensed-phase behavior of our model system. Interestingly, we find that our liquid-phase predictions are in excellent agreement with recent experimental reports on chiral self-sorting in isotropic liquids. From this perspective, our model demonstrates accurate predictive capabilities, as well as a platform for understanding the microscopic origins of a variety of chiral phenomena. In a broader context, we anticipate that this class of models will be relevant to chirality-dominated areas such as the pharmaceutical industry and pre-biotic geochemistry.

  12. Developing a Practical Chiral Toolbox for Asymmetric Catalytic Reactions

    Institute of Scientific and Technical Information of China (English)

    ZHANG XuMu

    2001-01-01

    @@ Chiral Quest's Toolbox Approach: During the last several decades, chemists have made major progress in discovering man-made catalysts to perform challenging asymmetric transformations. However, there is no universal chiral ligand or catalyst for solving problems in enantioselective transformations. The focus of Chiral Quest's research is to develop a useful chiral toolbox for strategically important asymmetric catalytic reactions by inventing a diverse set of novel chiral ligands and combining them with transition metals as effective enantioselective catalysts. The toolbox approach addresses significant problems in organic stereochemistry and has resulted in practical methods for the synthesis of chiral pharmaceuticals and agrochemicals

  13. Developing a Practical Chiral Toolbox for Asymmetric Catalytic Reactions

    Institute of Scientific and Technical Information of China (English)

    ZHANG; XuMu

    2001-01-01

    Chiral Quest's Toolbox Approach: During the last several decades, chemists have made major progress in discovering man-made catalysts to perform challenging asymmetric transformations. However, there is no universal chiral ligand or catalyst for solving problems in enantioselective transformations. The focus of Chiral Quest's research is to develop a useful chiral toolbox for strategically important asymmetric catalytic reactions by inventing a diverse set of novel chiral ligands and combining them with transition metals as effective enantioselective catalysts. The toolbox approach addresses significant problems in organic stereochemistry and has resulted in practical methods for the synthesis of chiral pharmaceuticals and agrochemicals  ……

  14. Enantioselectively controlled release of chiral drug (metoprolol) using chiral mesoporous silica materials

    Science.gov (United States)

    Guo, Zhen; Du, Yu; Liu, Xianbin; Ng, Siu-Choon; Chen, Yuan; Yang, Yanhui

    2010-04-01

    Chiral porous materials have attracted burgeoning attention on account of their potential applications in many areas, such as enantioseparation, chiral catalysis, chemical sensors and drug delivery. In this report, chiral mesoporous silica (CMS) materials with various pore sizes and structures were prepared using conventional achiral templates (other than chiral surfactant) and a chiral cobalt complex as co-template. The synthesized CMS materials were characterized by x-ray diffraction, nitrogen physisorption, scanning electron microscope and transmission electron microscope. These CMS materials, as carriers, were demonstrated to be able to control the enantioselective release of a representative chiral drug (metoprolol). The release kinetics, as modeled by the power law equation, suggested that the release profiles of metoprolol were remarkably dependent on the pore diameter and pore structure of CMS materials. More importantly, R- and S-enantiomers of metoprolol exhibited different release kinetics on CMS compared to the corresponding achiral mesoporous silica (ACMS), attributable to the existence of local chirality on the pore wall surface of CMS materials. The chirality of CMS materials on a molecular level was further substantiated by vibrational circular dichroism measurements.

  15. Enantioselectively controlled release of chiral drug (metoprolol) using chiral mesoporous silica materials

    Energy Technology Data Exchange (ETDEWEB)

    Guo Zhen; Liu Xianbin; Ng, Siu-Choon; Chen Yuan; Yang Yanhui [School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore 637459 (Singapore); Du Yu, E-mail: du_yu@jlu.edu.cn, E-mail: yhyang@ntu.edu.sg [College of Electronic Science and Engineering, Jilin University, Changchun 130012 (China)

    2010-04-23

    Chiral porous materials have attracted burgeoning attention on account of their potential applications in many areas, such as enantioseparation, chiral catalysis, chemical sensors and drug delivery. In this report, chiral mesoporous silica (CMS) materials with various pore sizes and structures were prepared using conventional achiral templates (other than chiral surfactant) and a chiral cobalt complex as co-template. The synthesized CMS materials were characterized by x-ray diffraction, nitrogen physisorption, scanning electron microscope and transmission electron microscope. These CMS materials, as carriers, were demonstrated to be able to control the enantioselective release of a representative chiral drug (metoprolol). The release kinetics, as modeled by the power law equation, suggested that the release profiles of metoprolol were remarkably dependent on the pore diameter and pore structure of CMS materials. More importantly, R- and S-enantiomers of metoprolol exhibited different release kinetics on CMS compared to the corresponding achiral mesoporous silica (ACMS), attributable to the existence of local chirality on the pore wall surface of CMS materials. The chirality of CMS materials on a molecular level was further substantiated by vibrational circular dichroism measurements.

  16. Novel electrochemical method for the characterization of the degree of chirality in chiral polyaniline.

    Science.gov (United States)

    Feng, Zhang; Li, Ma; Yan, Yang; Jihai, Tang; Xiao, Li; Wanglin, Li

    2013-01-01

    A novel method to indicate the degree of chirality in polyaniline (PANI) was developed. The (D-camphorsulfonic acid)- and (HCl)-PANI-based electrodes exhibited significantly different electrochemical performances in D- and L-Alanine (Ala) aqueous solution, respectively, which can be used for the characterization the optical activity of chiral PANI. Cyclic voltammogram, tafel, and open circuit potential of PANI-based electrodes were measured within D- and L-Ala electrolyte solution, respectively. The open circuit potentials under different reacting conditions were analyzed by Doblhofer model formula, in which [C(+)](poly1)/[C(+)](poly2) was used as a parameter to characterize the degree of chirality in chiral PANI. The results showed that [C(+)](poly1)/[C(+)](poly2) can be increased with increasing concentrations of (1S)-(+)- and (1R)-(-)-10-camphorsulfonic acid. In addition, we detected that appropriate response time and lower temperature are necessary to improve the degree of chirality.

  17. Chiral dynamics and peripheral transverse densities

    Energy Technology Data Exchange (ETDEWEB)

    Granados, Carlos G. [Uppsala University (Sweden); Weiss, Christian [JLAB, Newport News, VA (United States)

    2014-01-01

    In the partonic (or light-front) description of relativistic systems the electromagnetic form factors are expressed in terms of frame-independent charge and magnetization densities in transverse space. This formulation allows one to identify the chiral components of nucleon structure as the peripheral densities at transverse distances b = O(M{sub {pi}}{sup -1}) and compute them in a parametrically controlled manner. A dispersion relation connects the large-distance behavior of the transverse charge and magnetization densities to the spectral functions of the Dirac and Pauli form factors near the two--pion threshold at timelike t = 4 M{ sub {pi}}{sup 2}, which can be computed in relativistic chiral effective field theory. Using the leading-order approximation we (a) derive the asymptotic behavior (Yukawa tail) of the isovector transverse densities in the "chiral" region b = O(M{sub {pi}}{sup -1}) and the "molecular" region b = O(M{sub N}{sup 2}/M{sub {pi}}{sup 3}); (b) perform the heavy-baryon expansion of the transverse densities; (c) explain the relative magnitude of the peripheral charge and magnetization densities in a simple mechanical picture; (d) include Delta isobar intermediate states and study the peripheral transverse densities in the large-N{ sub c} limit of QCD; (e) quantify the region of transverse distances where the chiral components of the densities are numerically dominant; (f) calculate the chiral divergences of the b{sup 2}-weighted moments of the isovector transverse densities (charge and anomalous magnetic radii) in the limit M{sub {pi}} -> 0 and determine their spatial support. Our approach provides a concise formulation of the spatial structure of the nucleon's chiral component and offers new insights into basic properties of the chiral expansion. It relates the information extracted from low-t elastic form factors to the generalized parton distributions probed in peripheral high-energy scattering processes.

  18. Chirality, photochemistry and the detection of amino acids in interstellar ice analogues and comets.

    Science.gov (United States)

    Evans, Amanda C; Meinert, Cornelia; Giri, Chaitanya; Goesmann, Fred; Meierhenrich, Uwe J

    2012-08-21

    The primordial appearance of chiral amino acids was an essential component of the asymmetric evolution of life on Earth. In this tutorial review we will explore the original life-generating, symmetry-breaking event and summarise recent thoughts on the origin of enantiomeric excess in the universe. We will then highlight the transfer of asymmetry from chiral photons to racemic amino acids and elucidate current experimental data on the photochemical synthesis of amino and diamino acid structures in simulated interstellar and circumstellar ice environments. The chirality inherent within actual interstellar (cometary) ice environments will be considered in this discussion: in 2014 the Rosetta Lander Philae onboard the Rosetta space probe is planned to detach from the orbiter and soft-land on the surface of the nucleus of comet 67P/Churyumov-Gerasimenko. It is equipped for the in situ enantioselective analysis of chiral prebiotic organic species in cometary ices. The scientific design of this mission will therefore be presented in the context of analysing the formation of amino acid structures within interstellar ice analogues as a means towards furthering understanding of the origin of asymmetric biological molecules.

  19. Threshold pion production in proton-proton collisions at NNLO in chiral EFT

    CERN Document Server

    Baru, V; Filin, A A; Hanhart, C; Krebs, H; Myhrer, F

    2016-01-01

    The reaction $NN \\to NN \\pi$ offers a good testing ground for chiral effective field theory at intermediate energies. It challenges our understanding of the first inelastic channel in nucleon-nucleon scattering and of the charge-symmetry breaking pattern in hadronic reactions. In our previous studies, we presented a complete calculation of the pion-production operator for s-wave pions up-to-and-including next-to-next-to-leading order (NNLO) in the formulation of chiral effective field theory, which includes pions, nucleons and $\\Delta(1232)$ degrees of freedom. In this paper we calculate the near threshold cross section for the $pp \\to d \\pi^{+}$ reaction by performing the convolution of the obtained operators with nuclear wave functions based on modern phenomenological and chiral potentials. The available chiral $NN$ wave functions are constructed with a cutoff comparable with the momentum transfer scale inherent in pion production reactions. Hence, a significant portion of the dynamical intermediate-range p...

  20. Diffusion of active chiral particles

    Science.gov (United States)

    Sevilla, Francisco J.

    2016-12-01

    The diffusion of chiral active Brownian particles in three-dimensional space is studied analytically, by consideration of the corresponding Fokker-Planck equation for the probability density of finding a particle at position x and moving along the direction v ̂ at time t , and numerically, by the use of Langevin dynamics simulations. The analysis is focused on the marginal probability density of finding a particle at a given location and at a given time (independently of its direction of motion), which is found from an infinite hierarchy of differential-recurrence relations for the coefficients that appear in the multipole expansion of the probability distribution, which contains the whole kinematic information. This approach allows the explicit calculation of the time dependence of the mean-squared displacement and the time dependence of the kurtosis of the marginal probability distribution, quantities from which the effective diffusion coefficient and the "shape" of the positions distribution are examined. Oscillations between two characteristic values were found in the time evolution of the kurtosis, namely, between the value that corresponds to a Gaussian and the one that corresponds to a distribution of spherical shell shape. In the case of an ensemble of particles, each one rotating around a uniformly distributed random axis, evidence is found of the so-called effect "anomalous, yet Brownian, diffusion," for which particles follow a non-Gaussian distribution for the positions yet the mean-squared displacement is a linear function of time.

  1. Magnetohydrodynamics of Chiral Relativistic Fluids

    CERN Document Server

    Boyarsky, Alexey; Ruchayskiy, Oleg

    2015-01-01

    We study the dynamics of a plasma of charged relativistic fermions at very high temperature $T\\gg m$, where $m$ is the fermion mass, coupled to the electromagnetic field. In particular, we derive a magneto-hydrodynamical description of the evolution of such a plasma. We show that, as compared to conventional MHD for a plasma of non-relativistic particles, the hydrodynamical description of the relativistic plasma involves new degrees of freedom described by a pseudo-scalar field originating in a local asymmetry in the densities of left-handed and right-handed fermions. This field can be interpreted as an effective axion field. Taking into account the chiral anomaly we present dynamical equations for the evolution of this field, as well as of other fields appearing in the MHD description of the plasma. Due to its non-linear coupling to helical magnetic fields, the axion field significantly affects the dynamics of a magnetized plasma and can give rise to a novel type of inverse cascade.

  2. Chiral heteropoly blues and controllable switching of achiral polyoxometalate clusters.

    Science.gov (United States)

    Wang, Yizhan; Li, Haolong; Wu, Che; Yang, Yang; Shi, Lei; Wu, Lixin

    2013-04-22

    Managing the blues: Chiral heteropoly blues of achiral polyoxometalate clusters were created through an intermolecular interaction with a chiral organic compound. Controllable chiroptical switching of the cluster complexes was possible through reversible photochromism of the polyoxometalates (see picture).

  3. A web site for calculating the degree of chirality.

    Science.gov (United States)

    Zayit, Amir; Pinsky, Mark; Elgavi, Hadassah; Dryzun, Chaim; Avnir, David

    2011-01-01

    The web site, http://www.csm.huji.ac.il/, uses the Continuous Chirality Measure to evaluate quantitatively the degree of chirality of a molecule, a structure, a fragment. The value of this measure ranges from zero, the molecule is achiral, to higher values (the upper limit is 100); the higher the chirality value, the more chiral the molecule is. The measure is based on the distance between the chiral molecule and the nearest structure that is achiral. Questions such as the following can be addressed: by how much is one molecule more chiral than the other? how does chirality change along conformational motions? is there a correlation between chirality and enantioselectivity in a series of molecules? Both elementary and advanced features are offered. Related calculation options are the symmetry measures and shape measures.

  4. Spontaneous chiral symmetry breaking in the Tayler instability

    CERN Document Server

    Del Sordo, Fabio; Brandenburg, Axel; Mitra, Dhrubaditya

    2011-01-01

    The chiral symmetry breaking properties of the Tayler instability are discussed. Effective amplitude equations are determined in one case. This model has three free parameters that are determined numerically. Comparison with chiral symmetry breaking in biochemistry is made.

  5. Enantioselective catalytic syntheses of alpha-branched chiral amines

    DEFF Research Database (Denmark)

    Brase, S.; Baumann, T.; Dahmen, S.

    2007-01-01

    Chiral amines play a pivotal role in fine chemical and natural product syntheses and the design of novel materials.......Chiral amines play a pivotal role in fine chemical and natural product syntheses and the design of novel materials....

  6. Radiation and scattering from thin wires in chiral media

    Science.gov (United States)

    Jaggard, Dwight L.; Liu, John C.; Grot, Annette; Pelet, Philippe

    1992-11-01

    The effect of chirality on thin win antennas and scatterers in unbounded chiral material is examined through the application of fundamental principles and the examination of several canonical examples. In particular, the interplay between normalized chirality and wire length is investigated to classify radiation and scattering patterns. Chirality induces rapid decay in the currents on such wires, resulting in mountain-peak-shaped current distributions characteristic of wire antennas and bow-tie-shaped current distributions characteristic of wire scatterers of sufficient length. These current distributions, in turn, cause radiation and scattering patterns which exhibit a chirality-dependent forbidden zone for both antennas and scatterers. In this zone, the fields are greatly reduced. These distinctive results lead naturally to the classification of wire scattering and radiation into subchiral, chiral, and superchiral regimes. All results are understood from the underlying physical principles of electromagnetic chirality, and are related to values of a dimensionless parameter involving normalized chirality and normalized wire length.

  7. METHODS DEVELOPMENT FOR THE ANALYSIS OF CHIRAL PESTICIDES

    Science.gov (United States)

    Chiral compounds exist as a pair of nonsuperimposable mirror images called enantiomers. Enantiomers have identical physical-chemical properties, but their interactions with other chiral molecules, toxicity, biodegradation, and fate are often different. Many pharmaceutical com...

  8. Chiral Hyperbolic Metamaterial as A Robust Photonic Topological Insulator

    CERN Document Server

    Gao, Wenlong; Yang, Biao; Liu, Fu; Fang, Fengzhou; Li, Jensen; Zhang, Shuang

    2014-01-01

    Topological insulators represent a new phase of matter which remain insulating for bulk electron transport while supporting protected one-way edge states. Recently it has been shown that the concept of topological order can also be transferred to photonic systems. Thus far however, photonic topological insulators have been realized almost exclusively in periodic structures where the specific connection between lattice symmetry and the band structure plays a critical role. Here we demonstrate robust photonic topological order in a homogenous medium described by only a few effective electromagnetic parameters, and not requiring the presence of an external magnetic field. By combining hyperbolicity and chirality, we show that a topologically nontrivial gap appears between the equi-frequency surfaces which support one-way edge states. The effective medium approach towards topological insulation paves the way for highly compact one-way transportation of electromagnetic waves in integrated photonic circuits.

  9. The Practical Asymmetric Syntheses of Key Chiral Intermediates of Chiral Drug from Four-Carbon Chiral Pool

    Institute of Scientific and Technical Information of China (English)

    MI AiQiao; LIN WenQin; HE Zhe; JIN Yi; JIANG YaoZhong

    2001-01-01

    @@ (S)-or (R)-2-Amino-4-phenylbutyric acid and (S)-or (R)-2-hydroxy-4-phenylbutyric acid and their ethyl esters are key chiral intermediates for the preparation of angiotensin converting enzyme inhibitors (ACEI) and other chiral drugs. Their practically asymmetric synthetic methods in large scale from four-carbon chiral pool, commercially available L-aspartic acid and L-malic acid, will be presented (as scheme). (S)-2-Amino-4-phenylbutyric acid and its ethyl ester hydrochloride were prepared from the easily available L-aspartic acid via activation by forming anhydride hydrochloride, Friedel-Crafts reaction with benzene, hydrogenolysis and esterification with ethanol in the presence of thionyl chloride in overall yield of 80% and 73.6% respectively with 99% ee. We first used amino acid anhydride hydrochloride as the acylating agent in Friedel-Crafts reaction without racemization. [1

  10. The Practical Asymmetric Syntheses of Key Chiral Intermediates of Chiral Drug from Four-Carbon Chiral Pool

    Institute of Scientific and Technical Information of China (English)

    MI; AiQiao

    2001-01-01

    (S)-or (R)-2-Amino-4-phenylbutyric acid and (S)-or (R)-2-hydroxy-4-phenylbutyric acid and their ethyl esters are key chiral intermediates for the preparation of angiotensin converting enzyme inhibitors (ACEI) and other chiral drugs. Their practically asymmetric synthetic methods in large scale from four-carbon chiral pool, commercially available L-aspartic acid and L-malic acid, will be presented (as scheme).  (S)-2-Amino-4-phenylbutyric acid and its ethyl ester hydrochloride were prepared from the easily available L-aspartic acid via activation by forming anhydride hydrochloride, Friedel-Crafts reaction with benzene, hydrogenolysis and esterification with ethanol in the presence of thionyl chloride in overall yield of 80% and 73.6% respectively with 99% ee. We first used amino acid anhydride hydrochloride as the acylating agent in Friedel-Crafts reaction without racemization. [1]……

  11. Rotating pigment cells exhibit an intrinsic chirality.

    Science.gov (United States)

    Yamanaka, Hiroaki; Kondo, Shigeru

    2015-01-01

    In multicellular organisms, cell properties, such as shape, size and function are important in morphogenesis and physiological functions. Recently, 'cellular chirality' has attracted attention as a cellular property because it can cause asymmetry in the bodies of animals. In recent in vitro studies, the left-right bias of cellular migration and of autonomous arrangement of cells under some specific culture conditions were discovered. However, it is difficult to identify the molecular mechanism underlying their intrinsic chirality because the left-right bias observed to date is subtle or is manifested in the stable orientation of cells. Here, we report that zebrafish (Danio rerio) melanophores exhibit clear cellular chirality by unidirectional counterclockwise rotational movement under isolated conditions without any special settings. The chirality is intrinsic to melanophores because the direction of the cellular rotation was not affected by the type of extracellular matrix. We further found that the cellular rotation was generated as a counter action of the clockwise movement of actin cytoskeleton. It suggested that the mechanism that directs actin cytoskeleton in the clockwise direction is pivotal for determining cellular chirality.

  12. [Preparations and biological properties of chiral compounds].

    Science.gov (United States)

    Sinko, Goran

    2005-12-01

    Enantiomers of chiral compounds may express various biological activities and also different toxicities. Examples of different pharmacological effects of some chiral drugs such as fluoxetine, penicillamine, ibuprofen and albuterol are provided in this paper. Due to possible differences in activity, the chiral drugs are required to be pure enantiomeric compounds in order to be more effective and safer to use. In the laboratory, enantiomers are mainly synthesized as racemates (an equimolar mixture of enantiomers) while in biological pathways only one enantiomeric form is produced, such as amino acids, sugars and lipids. This paper presents the principles of chirality, general information about enantiomers and their biological aspects. It gives an outline of stereoselective methods for chromatographic resolution of enantiomers with stereoselective protein stationary phases, i.e. capillary electrochromatography (CEC) and high performance liquid chromatography (HPLC). The use of enzyme biotransformations (hydrolysis, oxidation and reduction) in chiral syntheses of carboxyl-, phosphoryl- or beta-hydroxy esters, alcohols, epoxides and cis-carboxyl sulphoxide is described. This article also includes an example of lipase stereoselectivity improvement by amino acid mutations within the enzyme active site.

  13. On the chiral imbalance and Weibel instabilities

    Science.gov (United States)

    Kumar, Avdhesh; Bhatt, Jitesh R.; Kaw, P. K.

    2016-06-01

    We study the chiral-imbalance and the Weibel instabilities in presence of the quantum anomaly using the Berry-curvature modified kinetic equation. We argue that in many realistic situations, e.g. relativistic heavy-ion collisions, both the instabilities can occur simultaneously. The Weibel instability depends on the momentum anisotropy parameter ξ and the angle (θn) between the propagation vector and the anisotropy direction. It has maximum growth rate at θn = 0 while θn = π / 2 corresponds to a damping. On the other hand the pure chiral-imbalance instability occurs in an isotropic plasma and depends on difference between the chiral chemical potentials of right and left-handed particles. It is shown that when θn = 0, only for a very small values of the anisotropic parameter ξ ∼ξc, growth rates of the both instabilities are comparable. For the cases ξc Weibel modes dominate over the chiral-imbalance instability if μ5 / T ≤ 1. However, when μ5 / T ≥ 1, it is possible to have dominance of the chiral-imbalance modes at certain values of θn for an arbitrary ξ.

  14. Chiral effects in the confining QCD vacuum

    CERN Document Server

    Simonov, Yu A

    1994-01-01

    Configurations are introduced into the standard instanton vacuum model. This drastically improves theoretical properties of the vacuum: instanton size density $d(\\rho)$ stabilizes at $\\rho\\sim 0.2 fm$, all chiral effects are formulated in a gauge-invariant way and quarks are confined. An interesting interplay of chiral and confining dynamics is observed; for the realistic values of parameters the Georgi-Manohar picture emerges with chiral radius $R_{ch}\\sim \\rho\\sim 0.2 fm$ much less than confining radius $R_c\\sim$ hadron radius $\\sim 1 fm$. In the limit $R_{ch}\\ll R_c$ the chiral mass $M_{ch}(p)$ is unaffected by confinement and can be taken in the local limit $M_{ch}(p=0)$. Different types of effective chiral Lagrangians (ECL) are obtained, containing all or a part of gluon, quark and Nambu--Goldstone--meson fields. The ECL are manifestly gauge--invariant and in the limit of no gluon fields coincide with those found previously. The problem of the double role of the pion -- as a Goldstone meson or as a $q\\ba...

  15. Novel Lifshitz point for chiral transition in the magnetic field

    Directory of Open Access Journals (Sweden)

    Toshitaka Tatsumi

    2015-04-01

    Full Text Available Based on the generalized Ginzburg–Landau theory, chiral phase transition is discussed in the presence of magnetic field. Considering the chiral density wave we show that chiral anomaly gives rise to an inhomogeneous chiral phase for nonzero quark-number chemical potential. Novel Lifshitz point appears on the vanishing chemical potential line, which may be directly explored by the lattice QCD simulation.

  16. New Terms for Compact Form of Electroweak Chiral Lagrangian

    Institute of Scientific and Technical Information of China (English)

    YE Wei; ZHANG Hong-Hao; YANG Hong-Wei; YAN Wen-Bin; CHEN Na; J.K. Parry; LI Xue-Song

    2008-01-01

    The compact form of the electroweak chiral Lagrangian is a reformulation of its original form and is expressed in terms of chiral rotated electroweak gauge fields, which is crucial for relating the information of underlying theories to the coefficients of the low-energy effective Lagrangian. However the compact form obtained in previous works is not complete. In this letter we add several new chiral invariant terms to it and discuss the contributions of these terms to the original electroweak chiral Lagrangian.

  17. Inhomogeneous Polyakov loop induced by inhomogeneous chiral condensates

    Directory of Open Access Journals (Sweden)

    Tomoya Hayata

    2015-05-01

    Full Text Available We study the spatial inhomogeneity of the Polyakov loop induced by inhomogeneous chiral condensates. We formulate an effective model of gluons on the background fields of chiral condensates, and perform its lattice simulation. On the background of inhomogeneous chiral condensates, the Polyakov loop exhibits an in-phase spatial oscillation with the chiral condensates. We also analyze the heavy quark potential and show that the inhomogeneous Polyakov loop indicates the inhomogeneous confinement of heavy quarks.

  18. Inhomogeneous Polyakov loop induced by inhomogeneous chiral condensates

    Energy Technology Data Exchange (ETDEWEB)

    Hayata, Tomoya, E-mail: hayata@riken.jp [Department of Physics, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Theoretical Research Division, Nishina Center, RIKEN, Wako, Saitama 351-0198 (Japan); Yamamoto, Arata [Department of Physics, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Theoretical Research Division, Nishina Center, RIKEN, Wako, Saitama 351-0198 (Japan)

    2015-05-11

    We study the spatial inhomogeneity of the Polyakov loop induced by inhomogeneous chiral condensates. We formulate an effective model of gluons on the background fields of chiral condensates, and perform its lattice simulation. On the background of inhomogeneous chiral condensates, the Polyakov loop exhibits an in-phase spatial oscillation with the chiral condensates. We also analyze the heavy quark potential and show that the inhomogeneous Polyakov loop indicates the inhomogeneous confinement of heavy quarks.

  19. Emerging functional chiral microporous materials: synthetic strategies and enantioselective separations

    Directory of Open Access Journals (Sweden)

    Ming Xue

    2016-11-01

    Full Text Available In recent years, chiral microporous materials with open pores have attracted much attention because of their potential applications in enantioselective separation and catalysis. This review summarizes the recent advances on chiral microporous materials, such as metal-organic frameworks (MOFs, hydrogen-bonded organic frameworks (HOFs and covalent organic frameworks (COFs. We will introduce the synthetic strategies in detail and highlight the current status of chiral microporous materials on solid enantioselective adsorption, chiral chromatography resolution and membrane separation.

  20. Acylation of Chiral Alcohols: A Simple Procedure for Chiral GC Analysis

    Directory of Open Access Journals (Sweden)

    Mireia Oromí-Farrús

    2012-01-01

    Full Text Available The use of iodine as a catalyst and either acetic or trifluoroacetic acid as a derivatizing reagent for determining the enantiomeric composition of acyclic and cyclic aliphatic chiral alcohols was investigated. Optimal conditions were selected according to the molar ratio of alcohol to acid, the reaction time, and the reaction temperature. Afterwards, chiral stability of chiral carbons was studied. Although no isomerization was observed when acetic acid was used, partial isomerization was detected with the trifluoroacetic acid. A series of chiral alcohols of a widely varying structural type were then derivatized with acetic acid using the optimal conditions. The resolution of the enantiomeric esters and the free chiral alcohols was measured using a capillary gas chromatograph equipped with a CP Chirasil-DEX CB column. The best resolutions were obtained with 2-pentyl acetates (α=3.00 and 2-hexyl acetates (α=1.95. This method provides a very simple and efficient experimental workup procedure for analyzing chiral alcohols by chiral-phase GC.

  1. Influence of Axial and Point Chirality in the Chiral Self-Assembly of Twin N-Annulated Perylenecarboxamides.

    Science.gov (United States)

    Buendía, Julia; Greciano, Elisa E; Sánchez, Luis

    2015-12-18

    The synthesis of three bis(N-annulated perylenecarboxamides) endowed with achiral or chiral side chains is reported. The restricted rotation of the perylene moieties yields atropisomers that can be separated by chiral HPLC. The CD spectra of the six stereoisomers show a dichroic pattern in a good solvent that changes drastically upon adding a poor solvent that favors the aggregation. The cooperative character of the supramolecular polymerization mechanism of 1-3 has been determined by denaturation experiments, which reveal that the formation of homochiral aggregates is favored over the formation of heterochiral aggregates. A complete set of amplification of chirality experiments have been carried out, revealing the preponderance of axial chirality over point chirality. The results presented herein shed relevant light on the structural conditions exhibited by molecular units endowed with different elements of asymmetry to generate chiral supramolecular structures and the supremacy of axial chirality over point chirality in the origin of homochirality.

  2. Asymmetric Catalytic Reactions Catalyzed by Chiral Titanium Complexes

    Institute of Scientific and Technical Information of China (English)

    FENG XiaoMing

    2001-01-01

    @@ Chiral titanium complexes is very importance catalyst to asymmetric catalytic reactions. A series of catalytic systems based on titanium-chiral ligands complexes has been reported. This presentation will discuss some of our recent progress on asymmetric catalytic reactions catalyzed by chiral titanium complexes.

  3. Meson Effects on the Chiral Condensate at Finite Density

    Institute of Scientific and Technical Information of China (English)

    HUANG Mei; ZHUANG Peng-Fei; ZHAO Wei-Qin

    2002-01-01

    Meson corrections on the chiral condensate up to next-to-leading order in a 1/Nc expansion at finite densityare investigated in the NJL model with explicit chiral symmetry breaking. Compared with mean-field results, the chiralphase transition is still of the first order while the properties near the critical density for chiral phase transition are foundto change significantly.

  4. Asymmetric Catalytic Reactions Catalyzed by Chiral Titanium Complexes

    Institute of Scientific and Technical Information of China (English)

    FENG; XiaoMing

    2001-01-01

    Chiral titanium complexes is very importance catalyst to asymmetric catalytic reactions. A series of catalytic systems based on titanium-chiral ligands complexes has been reported. This presentation will discuss some of our recent progress on asymmetric catalytic reactions catalyzed by chiral titanium complexes.  ……

  5. Chiral doublet bands and energy-level crossing

    Institute of Scientific and Technical Information of China (English)

    QI Bin; MENG Jie; ZHANG Shuang-Quan; WANG Shou-Yu; PENG Jing

    2009-01-01

    Different definitions for chiral doublet bands based on excitation energies, B(E2) and B(M1) respectively are discussed in the triaxial particle rotor model. For the ideal chiral geometry, the selection rules of the electromagnetic transitions in different band definitions are illustrated. It is also shown that the energy-level crossings between chiral doublet bands may occur.

  6. Electronic and optoelectronic devices based on chirality-enriched wafer-scale single-wall carbon nanotube thin films

    Science.gov (United States)

    Gao, Weilu; He, Xiaowei; Xie, Lijuan; Zhang, Qi; Haroz, Erik; Doorn, Stephen K.; Kono, Junichiro

    2015-03-01

    The unique and rich material properties of single-wall carbon nanotubes (SWCNTs) make them attractive for nano-electronic and optoelectronic applications. Slight changes in tube diameter and wrapping angle, defined by the chirality indices (n, m), can dramatically modify the bandstructure, which can be utilized for designing devices with tailored properties. However, it remains to be a challenge to fabricate macroscopic, single-chirality devices. Here, we introduce a simple way of producing chirality-enriched wafer-scale SWCNT films by combining recently developed solution-based polymer-modified sorting method and vacuum filtration. The produced thin films can be easily transferred onto any substrate to have a CMOS compatible wafer. We fabricated a transistor of (6,5)-enriched SWCNTs with an on/off ratio >103. Large-scale photothermoelectric-effect-based and photovoltaic-effect-based photodetectors made of (6,6)- and (6,5)-enriched films, respectively, will also be discussed.

  7. Chiral optical Tamm states at the boundary of the medium with helical symmetry of the dielectric tensor

    CERN Document Server

    Timofeev, Ivan V

    2016-01-01

    A new optical state is described both analytically and numerically at the boundary of a chiral medium with continuous helical symmetry of the dielectric tensor. The tangential wave number is assumed to be zero. The state appears to be localized near the boundary. It does not transfer energy along this boundary and falls off exponentially with the distance from the boundary. The field penetration into chiral medium is blocked at wavelengths close to the helical pitch and corresponding to the photonic band gap. The polarization of light near the boundary has the same sign of chirality as the helical medium. It is shown that the homogeneous environment, or the substrate must exhibit the anisotropic metallic reflection. Spectral manifestation of the state is determined by the angle between the optical axes at the interface. A realistic example is considered at the boundary of a cholesteric liquid crystal and a metal-dielectric anisotropic nanocomposite.

  8. Chiral optical Tamm states at the boundary of the medium with helical symmetry of the dielectric tensor

    Science.gov (United States)

    Timofeev, I. V.; Vetrov, S. Ya.

    2016-09-01

    A new optical state at the boundary of a chiral medium whose dielectric tensor has a helical symmetry is described analytically and numerically. The case of zero tangential wavenumber is considered. The state localized near the boundary does not transfer energy along this boundary and decreases exponentially with the distance from the boundary. The penetration of the field into the chiral medium is blocked at wavelengths corresponding to the photonic band gap and close to the pitch of the helix. The polarization of light near the boundary has the same sign of chirality as the helical symmetry. It is shown that the homogeneous environment or a substrate should exhibit anisotropic metallic reflection. The spectral manifestation of the state is determined by the angle between the optical axes of the media at the interface. A state at the interface between a cholesteric liquid crystal and an anisotropic metal-dielectric nanocomposite was considered as an example.

  9. Vector solitons in nonlinear isotropic chiral metamaterials

    CERN Document Server

    Tsitsas, N L; Frantzeskakis, D J

    2011-01-01

    Starting from the Maxwell equations, we used the reductive perturbation method to derive a system of two coupled nonlinear Schr\\"{o}dinger (NLS) equations for the two Beltrami components of the electromagnetic field propagating along a fixed direction in an isotropic nonlinear chiral metamaterial. With single-resonance Lorentz models for the permittivity and permeability and a Condon model for the chirality parameter, in certain spectral regimes, one of the two Beltrami components exhibits a negative real refractive index when nonlinearity is ignored and the chirality parameter is sufficiently large.We found that, inside such a spectral regime, there may exist a subregime wherein the system of the NLS equations can be approximated by the Manakov system. Bright-bright, dark-dark, and dark-bright vector solitons can be formed in that spectral subregime.

  10. Interference Phenomenon for Different Chiral Bosonization Schemes

    CERN Document Server

    Abreu, Everton M C; Abreu, Everton M C; Wotzasek, Clovis

    1998-01-01

    We study the relationship between different chiral bosonization schemes (CBS) in the context of the soldering formalism\\cite{MS}, that considers the phenomenon of interference in the quantum field theory\\cite{ABW}. This analysis is done in the framework put forward by Siegel\\cite{WS} and by Floreanini and Jackiw\\cite{FJ} (FJ). We propose a field redefinition that discloses the presence of a noton, a non dynamical field, in Siegel's formulation for chiral bosons. The presence of a noton in the Siegel CBS is a new and surprising result, that separates dynamics from symmetry by diagonalising the Siegel action into the FJ and the noton action. While the first describes the chiral dynamics, the noton carries the symmetry contents, acquiring dynamics upon quantization and is fully responsible for the Siegel anomaly. The diagonal representation proposed here is used to study the effect of quantum interference between gauged rightons and leftons.

  11. Vector solitons in nonlinear isotropic chiral metamaterials

    Energy Technology Data Exchange (ETDEWEB)

    Tsitsas, N L [School of Applied Mathematical and Physical Sciences, National Technical University of Athens, Zografos, Athens 15773 (Greece); Lakhtakia, A [Department of Engineering Science and Mechanics, Pennsylvania State University, University Park, PA 16802-6812 (United States); Frantzeskakis, D J, E-mail: dfrantz@phys.uoa.gr [Department of Physics, University of Athens, Panepistimiopolis, Zografos, Athens 15784 (Greece)

    2011-10-28

    Starting from the Maxwell equations, we used the reductive perturbation method to derive a system of two coupled nonlinear Schroedinger (NLS) equations for the two Beltrami components of the electromagnetic field propagating along a fixed direction in an isotropic nonlinear chiral metamaterial. With single-resonance Lorentz models for the permittivity and permeability and a Condon model for the chirality parameter, in certain spectral regimes, one of the two Beltrami components exhibits a negative-real refractive index when nonlinearity is ignored and the chirality parameter is sufficiently large. We found that, inside such a spectral regime, there may exist a subregime wherein the system of the NLS equations can be approximated by the Manakov system. Bright-bright, dark-dark, and dark-bright vector solitons can be formed in that spectral subregime. (paper)

  12. Hydrodynamics of the Chiral Dirac Spectrum

    CERN Document Server

    Liu, Yizhuang; Zahed, Ismail

    2016-01-01

    We derive a hydrodynamical description of the eigenvalues of the chiral Dirac spectrum in the vacuum and in the large $N$ (volume) limit. The linearized hydrodynamics supports sound waves. The stochastic relaxation of the eigenvalues is captured by a hydrodynamical instanton configuration which follows from a pertinent form of Euler equation. The relaxation from a phase of localized eigenvalues and unbroken chiral symmetry to a phase of de-localized eigenvalues and broken chiral symmetry occurs over a time set by the speed of sound. We show that the time is $\\Delta \\tau=\\pi\\rho(0)/2\\beta N$ with $\\rho(0)$ the spectral density at zero virtuality and $\\beta=1,2,4$ for the three Dyson ensembles that characterize QCD with different quark representations in the ergodic regime.

  13. Chiral specific electron vortex beam spectroscopy

    CERN Document Server

    Yuan, J; Babiker, M

    2013-01-01

    Electron vortex beams carry well-defined orbital angular momentum (OAM) about the propagation axis. Such beams are thus characterised by chirality features which make them potentially useful as probes of magnetic and other chiral materials. An analysis of the inelastic processes in which electron vortex beams interact with atoms and which involve OAM exchange is outlined, leading to the multipolar selection rules governing this chiral specific electron vortex beam spectroscopy. Our results show clearly that the selection rules are dependent on the dynamical state and location of the atoms involved. In the most favorable scenario, this form of electron spectroscopy can induce magnetic sublevel transitions which are commonly probed using circularly polarized photon beams.

  14. Energy Conservation and the Chiral Magnetic Effect

    CERN Document Server

    Kaplan, David B; Sen, Srimoyee

    2016-01-01

    We analyze the chiral magnetic effect in a neutral plasma from the point of view of energy conservation, and construct an effective potential for the growth of helical perturbations of the electromagnetic field. We show that a negative curvature at the origin of the potential, indicating instability of the plasma, is induced by a chiral asymmetry in electron Fermi energy, as opposed to number density, while the potential grows at large field value. It follows that the ground state for a plasma has zero magnetic helicity; a nonzero electron mass will allow an excited state of a plasma with nonzero helicity to relax to that ground state quickly. We conclude that a chiral plasma instability triggered by weak interactions is not a viable mechanism for explaining magnetic fields in neutron stars.

  15. Chiral scars in chaotic Dirac fermion systems.

    Science.gov (United States)

    Xu, Hongya; Huang, Liang; Lai, Ying-Cheng; Grebogi, Celso

    2013-02-08

    Do relativistic quantum scars in classically chaotic systems possess unique features that are not shared by nonrelativistic quantum scars? We report a class of relativistic quantum scars in massless Dirac fermion systems whose phases return to the original values or acquire a 2π change only after circulating twice about some classical unstable periodic orbits. We name such scars chiral scars, the successful identification of which has been facilitated tremendously by our development of an analytic, conformal-mapping-based method to calculate an unprecedentedly large number of eigenstates with high accuracy. Our semiclassical theory indicates that the physical origin of chiral scars can be attributed to a combined effect of chirality intrinsic to massless Dirac fermions and the geometry of the underlying classical orbit.

  16. Viscoelastic modes in chiral liquid crystals

    Indian Academy of Sciences (India)

    K A Suresh

    2003-08-01

    Viscoelastic properties of liquid crystals are very important for applications like display technology. However, there are not many direct techniques to study them. In this review, we describe our studies on the viscoelastic modes of some chiral liquid crystals using dynamic light scattering. We discuss viscoelastic modes corresponding to the C director fluctuations in the chiral smectic C phase and the behaviour of the Goldstone-mode near the chiral smectic C–smectic A phase transition. In cholesteric liquid crystals, we consider the director fluctuations in a wavevector range comparable to the inverse pitch of the cholesteric. Here, the study of the scattered light in the vicinity of the Bragg reflection using a novel geometry will be presented.

  17. Chiral bosonization for non-commutative fields

    CERN Document Server

    Das, A; Méndez, F; López-Sarrion, J; Das, Ashok; Gamboa, Jorge; M\\'endez, Fernando; L\\'opez-Sarri\\'on, Justo

    2004-01-01

    A model of chiral bosons on a non-commutative field space is constructed and new generalized bosonization (fermionization) rules for these fields are given. The conformal structure of the theory is characterized by a level of the Kac-Moody algebra equal to $(1+ \\theta^2)$ where $\\theta$ is the non-commutativity parameter and chiral bosons living in a non-commutative fields space are described by a rational conformal field theory with the central charge of the Virasoro algebra equal to 1. The non-commutative chiral bosons are shown to correspond to a free fermion moving with a speed equal to $ c^{\\prime} = c \\sqrt{1+\\theta^2} $ where $c$ is the speed of light. Lorentz invariance remains intact if $c$ is rescaled by $c \\to c^{\\prime}$. The dispersion relation for bosons and fermions, in this case, is given by $\\omega = c^{\\prime} | k|$.

  18. Chiral Perturbation Theory With Lattice Regularization

    CERN Document Server

    Ouimet, P P A

    2005-01-01

    In this work, alternative methods to regularize chiral perturbation theory are discussed. First, Long Distance Regularization will be considered in the presence of the decuplet of the lightest spin 32 baryons for several different observables. This serves motivation and introduction to the use of the lattice regulator for chiral perturbation theory. The mesonic, baryonic and anomalous sectors of chiral perturbation theory will be formulated on a lattice of space time points. The consistency of the lattice as a regulator will be discussed in the context of the meson and baryon masses. Order a effects will also be discussed for the baryon masses, sigma terms and magnetic moments. The work will close with an attempt to derive an effective Wess-Zumino-Witten Lagrangian for Wilson fermions at non-zero a. Following this discussion, there will be a proposal for a phenomenologically useful WZW Lagrangian at non-zero a.

  19. Chiral light by symmetric optical antennas

    CERN Document Server

    Mekonnen, Addis; Zubritskaya, Irina; Jönsson, Gustav Edman; Dmitriev, Alexandre

    2014-01-01

    Chirality is at the origin of life and is ubiquitous in nature. An object is deemed chiral if it is non-superimposable with its own mirror image. This relates to how circularly polarized light interacts with such object, a circular dichroism, the differential absorption of right and left circularly polarized light. According to the common understanding in biology, chemistry and physics, the circular dichroism results from an internal chiral structure or external symmetry breaking by illumination. We show that circular dichroism is possible with simple symmetric optical nanoantennas at symmetric illumination. We experimentally and theoretically demonstrate that two electromagnetic dipole-like modes with a phase lag, in principle, suffice to produce circular dichroism in achiral structure. Examples of the latter are all visible spectrum optical nanoantennas, symmetric nanoellipses and nanodimers. The simplicity and generality of this finding reveal a whole new significance of the electromagnetic design at a nan...

  20. Chiral Liquid Crystals: Structures, Phases, Effects

    Directory of Open Access Journals (Sweden)

    Ingo Dierking

    2014-06-01

    Full Text Available The introduction of chirality, i.e., the lack of mirror symmetry, has a profound effect on liquid crystals, not only on the molecular scale but also on the supermolecular scale and phase. I review these effects, which are related to the formation of supermolecular helicity, the occurrence of novel thermodynamic phases, as well as electro-optic effects which can only be observed in chiral liquid crystalline materials. In particular, I will discuss the formation of helical superstructures in cholesteric, Twist Grain Boundary and ferroelectric phases. As examples for the occurrence of novel phases the Blue Phases and Twist Grain Boundary phases are introduced. Chirality related effects are demonstrated through the occurrence of ferroelectricity in both thermotropic as well as lyotropic liquid crystals. Lack of mirror symmetry is also discussed briefly for some biopolymers such as cellulose and DNA, together with its influence on liquid crystalline behavior.

  1. Chiral Molecules Revisited by Broadband Microwave Spectroscopy

    Science.gov (United States)

    Schnell, Melanie

    2014-06-01

    Chiral molecules have fascinated chemists for more than 150 years. While their physical properties are to a very good approximation identical, the two enantiomers of a chiral molecule can have completely different (bio)chemical activities. For example, the right-handed enantiomer of carvone smells of spearmint while the left-handed one smells of caraway. In addition, the active components of many drugs are of one specific handedness, such as in the case of ibuprofen. However, in nature as well as in pharmaceutical applications, chiral molecules often exist in mixtures with other chiral molecules. The analysis of these complex mixtures to identify the molecular components, to determine which enantiomers are present, and to measure the enantiomeric excesses (ee) remains a challenging task for analytical chemistry, despite its importance for modern drug development. We present here a new method of differentiating enantiomers of chiral molecules in the gas phase based on broadband rotational spectroscopy. The phase of the acquired signal bares the signature of the enantiomer, as it depends upon the combined quantity, μ_a μ_b μ_c, which is of opposite sign between enantiomers. It thus also provides information on the absolute configuration of the particular enantiomer. Furthermore, the signal amplitude is proportional to the ee. A significant advantage of our technique is its inherent mixture compatibility due to the fingerprint-like character of rotational spectra. In this contribution, we will introduce the technique and present our latest results on chiral molecule spectroscopy and enantiomer differentiation. D. Patterson, M. Schnell, J.M. Doyle, Nature 497 (2013) 475-477 V.A. Shubert, D. Schmitz, D. Patterson, J.M. Doyle, M. Schnell, Angewandte Chemie International Edition 53 (2014) 1152-1155

  2. Revealing atropisomer axial chirality in drug discovery.

    Science.gov (United States)

    LaPlante, Steven R; Edwards, Paul J; Fader, Lee D; Jakalian, Araz; Hucke, Oliver

    2011-03-07

    An often overlooked source of chirality is atropisomerism, which results from slow rotation along a bond axis due to steric hindrance and/or electronic factors. If undetected or not managed properly, this time-dependent chirality has the potential to lead to serious consequences, because atropisomers can be present as distinct enantiomers or diastereoisomers with their attendant different properties. Herein we introduce a strategy to reveal and classify compounds that have atropisomeric chirality. Energy barriers to axial rotation were calculated using quantum mechanics, from which predicted high barriers could be experimentally validated. A calculated rotational energy barrier of 20 kcal mol(-1) was established as a suitable threshold to distinguish between atropisomers and non-atropisomers with a prediction accuracy of 86%. This methodology was applied to subsets of drug databases in the course of which atropisomeric drugs were identified. In addition, some drugs were exposed that were not yet known to have this chiral attribute. The most valuable utility of this tool will be to predict atropisomerism along the drug discovery pathway. When used in concert with our compound classification scheme, decisions can be made during early discovery stages such as "hit-to-lead" and "lead optimization," to foresee and validate the presence of atropisomers and to exercise options of removing, further stabilizing, or rendering the chiral axis of interest more freely rotatable via SAR design, thereby decreasing this potential liability within a compound series. The strategy can also improve drug development plans, such as determining whether a drug or series should be developed as a racemic mixture or as an isolated single compound. Moreover, the work described herein can be extended to other chemical fields that require the assessment of potential chiral axes.

  3. Spin-flavor structure of chiral-odd generalized parton distributions in the large-Nc limit

    Science.gov (United States)

    Schweitzer, P.; Weiss, C.

    2016-10-01

    We study the spin-flavor structure of the nucleon's chiral-odd generalized parton distributions (transversity GPDs) in the large-Nc limit of QCD. In contrast to the chiral-even case, only three combinations of the four chiral-odd GPDs are nonzero in the leading order of the 1 /Nc expansion: E¯T=ET+2 H˜T,HT , and E˜T. The degeneracy is explained by the absence of spin-orbit interactions correlating the transverse momentum transfer with the transverse quark spin. It can also be deduced from the natural Nc scaling of the quark-nucleon helicity amplitudes associated with the GPDs. In the GPD E¯T the flavor-singlet component u +d is leading in the 1 /Nc expansion, while in HT and E˜T it is the flavor-nonsinglet components u -d . The large-Nc relations are consistent with the spin-flavor structure extracted from hard exclusive π0 and η electroproduction data, if it is assumed that the processes are mediated by twist-3 amplitudes involving the chiral-odd GPDs and the chiral-odd pseudoscalar meson distribution amplitudes.

  4. Invariant Regularization of Supersymmetric Chiral Gauge Theory

    CERN Document Server

    Suzuki, H

    1999-01-01

    We present a regularization scheme which respects the supersymmetry and the maximal background gauge covariance in supersymmetric chiral gauge theories. When the anomaly cancellation condition is satisfied, the effective action in the superfield background field method automatically restores the gauge invariance without counterterms. The scheme also provides a background gauge covariant definition of composite operators that is especially useful in analyzing anomalies. We present several applications: The minimal consistent gauge anomaly; the super-chiral anomaly and the superconformal anomaly; as the corresponding anomalous commutators, the Konishi anomaly and an anomalous supersymmetric transformation law of the supercurrent (the ``central extension'' of N=1 supersymmetry algebra) and of the R-current.

  5. Chirality sensing with stereodynamic biphenolate zinc complexes.

    Science.gov (United States)

    Bentley, Keith W; de Los Santos, Zeus A; Weiss, Mary J; Wolf, Christian

    2015-10-01

    Two bidentate ligands consisting of a fluxional polyarylacetylene framework with terminal phenol groups were synthesized. Reaction with diethylzinc gives stereodynamic complexes that undergo distinct asymmetric transformation of the first kind upon binding of chiral amines and amino alcohols. The substrate-to-ligand chirality imprinting at the zinc coordination sphere results in characteristic circular dichroism signals that can be used for direct enantiomeric excess (ee) analysis. This chemosensing approach bears potential for high-throughput ee screening with small sample amounts and reduced solvent waste compared to traditional high-performance liquid chromatography methods.

  6. Chiral logarithms in the massless limit tamed.

    Science.gov (United States)

    Kivel, Nikolai; Polyakov, Maxim V; Vladimirov, Alexei

    2008-12-31

    We derive nonlinear recursion relations for the leading chiral logarithms (LLs) in massless theories. These relations not only provide a very efficient method of computation of LLs (e.g., the 33-loop contribution is calculated in a dozen of seconds on a PC) but also equip us with a powerful tool for the summation of the LLs. Our method is not limited to chiral perturbation theory only; it is pertinent to any nonrenormalizable effective field theory such as, for instance, the theory of critical phenomena, low-energy quantum gravity, etc.

  7. Chiral Surface Waves for Enhanced Circular Dichroism

    CERN Document Server

    Pellegrini, Giovanni; Celebrano, Michele; Duò, Lamberto; Biagioni, Paolo

    2016-01-01

    We present a novel chiral sensing platform that combines a one-dimensional photonic crystal design with a birefringent surface defect. The platform sustains simultaneous transverse electric and transverse magnetic surface modes, which are exploited to generate chiral surface waves. The present design provides homogeneous and superchiral fields of both handednesses over arbitrarily large areas in a wide spectral range, resulting in the enhancement of the circular dichroism signal by two orders of magnitude, thus paving the road toward the successful combination of surface-enhanced spectroscopies and electromagnetic superchirality.

  8. Rotating optical microcavities with broken chiral symmetry

    CERN Document Server

    Sarma, Raktim; Wiersig, Jan; Cao, Hui

    2014-01-01

    We demonstrate in open microcavities with broken chiral symmetry, quasi-degenerate pairs of co-propagating modes in a non-rotating cavity evolve to counter-propagating modes with rotation. The emission patterns change dramatically by rotation, due to distinct output directions of CW and CCW waves. By tuning the degree of spatial chirality, we maximize the sensitivity of microcavity emission to rotation. The rotation-induced change of emission is orders of magnitude larger than the Sagnac effect, pointing to a promising direction for ultrasmall optical gyroscopes.

  9. Heavy-tailed chiral random matrix theory

    Science.gov (United States)

    Kanazawa, Takuya

    2016-05-01

    We study an unconventional chiral random matrix model with a heavy-tailed probabilistic weight. The model is shown to exhibit chiral symmetry breaking with no bilinear condensate, in analogy to the Stern phase of QCD. We solve the model analytically and obtain the microscopic spectral density and the smallest eigenvalue distribution for an arbitrary number of flavors and arbitrary quark masses. Exotic behaviors such as non-decoupling of heavy flavors and a power-law tail of the smallest eigenvalue distribution are illustrated.

  10. Phenomenology of chiral damping in noncentrosymmetric magnets

    KAUST Repository

    Akosa, Collins Ashu

    2016-06-21

    A phenomenology of magnetic chiral damping is proposed in the context of magnetic materials lacking inversion symmetry. We show that the magnetic damping tensor acquires a component linear in magnetization gradient in the form of Lifshitz invariants. We propose different microscopic mechanisms that can produce such a damping in ferromagnetic metals, among which local spin pumping in the presence of an anomalous Hall effect and an effective “s-d” Dzyaloshinskii-Moriya antisymmetric exchange. The implication of this chiral damping in terms of domain-wall motion is investigated in the flow and creep regimes.

  11. Dynamics of the chiral phase transition

    CERN Document Server

    van Hees, H; Meistrenko, A; Greiner, C

    2013-01-01

    The intention of this study is the search for signatures of the chiral phase transition in heavy-ion collisions. To investigate the impact of fluctuations, e.g., of the baryon number, at the transition or at a critical point, the linear sigma model is treated in a dynamical (3+1)-dimensional numerical simulation. Chiral fields are approximated as classical mean fields, and quarks are described as quasi particles in a Vlasov equation. Additional dynamics is implemented by quark-quark and quark-sigma-field interactions. For a consistent description of field-particle interactions, a new Monte-Carlo-Langevin-like formalism has been developed and is discussed.

  12. Chirality effects on 2D phase transitions

    DEFF Research Database (Denmark)

    Scalas, E.; Brezesinski, G.; Möhwald, H.

    1996-01-01

    -nearest neighbours (NNN) and an NNN-distorted lattice is observed. At 5 degrees C, the transition pressure is 15 mN m(-1), whereas at 20 degrees C it is 18 mN m(-1). Chirality destroys this transition: the pure enantiomer always exhibits an oblique lattice with tilted molecules, and the azimuths of tilt...... and distortion continuously vary from a direction close to NN to a direction close to NNN. The nature of the phase transition and the influence of chirality on it are discussed within the framework of Landau's theory of phase transitions....

  13. Heavy-tailed chiral random matrix theory

    CERN Document Server

    Kanazawa, Takuya

    2016-01-01

    We study an unconventional chiral random matrix model with a heavy-tailed probabilistic weight. The model is shown to exhibit chiral symmetry breaking with no bilinear condensate, in analogy to the Stern phase of QCD. We solve the model analytically and obtain the microscopic spectral density and the smallest eigenvalue distribution for an arbitrary number of flavors and arbitrary quark masses. Exotic behaviors such as non-decoupling of heavy flavors and a power-law tail of the smallest eigenvalue distribution are illustrated.

  14. Vector Meson Masses in Chiral Perturbation Theory

    CERN Document Server

    Bijnens, J; Talavera, P

    1997-01-01

    We discuss the vector meson masses within the context of Chiral Perturbation Theory performing an expansion in terms of the momenta, quark masses and 1/Nc. We extend the previous analysis to include isospin breaking effects and also include up to order p^4. We discuss vector meson chiral perturbation theory in some detail and present a derivation from a relativistic lagrangian. The unknown coefficients are estimated in various ways. We also discuss the relevance of electromagnetic corrections and the implications of the present calculation for the determination of quark masses.

  15. Probing Chiral Interactions in Light Nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Nogga, A; Barrett, B R; Meissner, U; Witala, H; Epelbaum, E; Kamada, H; Navratil, P; Glockle, W; Vary, J P

    2004-01-08

    Chiral two- and three-nucleon interactions are studied in a few-nucleon systems. We investigate the cut-off dependence and convergence with respect to the chiral expansion. It is pointed out that the spectra of light nuclei are sensitive to the three-nucleon force structure. As an example, we present calculations of the 1{sup +} and 3{sup +} states of {sup 6}Li using the no-core shell model approach. The results show contributions of the next-to-next-to-leading order terms to the spectra, which are not correlated to the three-nucleon binding energy prediction.

  16. Pentaquarks in chiral color dielectric model

    Indian Academy of Sciences (India)

    S C Pathak

    2006-04-01

    Recent experiments indicate that a narrow baryonic state having strangeness +1 and mass of about 1540 MeV may be existing. Such a state was predicted in chiral model by Diakonov et al. In this work I compute the mass and width of this state in chiral color dielectric model. I show that the computed width is about 30 MeV. I find that the mass of the state can be fitted to the experimentally observed mass by invoking a color neutral vector field and its interaction with the quarks.

  17. Speciation and gene flow between snails of opposite chirality.

    Directory of Open Access Journals (Sweden)

    Angus Davison

    2005-09-01

    Full Text Available Left-right asymmetry in snails is intriguing because individuals of opposite chirality are either unable to mate or can only mate with difficulty, so could be reproductively isolated from each other. We have therefore investigated chiral evolution in the Japanese land snail genus Euhadra to understand whether changes in chirality have promoted speciation. In particular, we aimed to understand the effect of the maternal inheritance of chirality on reproductive isolation and gene flow. We found that the mitochondrial DNA phylogeny of Euhadra is consistent with a single, relatively ancient evolution of sinistral species and suggests either recent "single-gene speciation" or gene flow between chiral morphs that are unable to mate. To clarify the conditions under which new chiral morphs might evolve and whether single-gene speciation can occur, we developed a mathematical model that is relevant to any maternal-effect gene. The model shows that reproductive character displacement can promote the evolution of new chiral morphs, tending to counteract the positive frequency-dependent selection that would otherwise drive the more common chiral morph to fixation. This therefore suggests a general mechanism as to how chiral variation arises in snails. In populations that contain both chiral morphs, two different situations are then possible. In the first, gene flow is substantial between morphs even without interchiral mating, because of the maternal inheritance of chirality. In the second, reproductive isolation is possible but unstable, and will also lead to gene flow if intrachiral matings occasionally produce offspring with the opposite chirality. Together, the results imply that speciation by chiral reversal is only meaningful in the context of a complex biogeographical process, and so must usually involve other factors. In order to understand the roles of reproductive character displacement and gene flow in the chiral evolution of Euhadra, it will be

  18. Threshold pion production in proton-proton collisions at NNLO in chiral EFT

    Energy Technology Data Exchange (ETDEWEB)

    Baru, V. [Ruhr-Universitaet Bochum, Institut fuer Theoretische Physik II, Bochum (Germany); Institute for Theoretical and Experimental Physics, Moscow (Russian Federation); Epelbaum, E.; Filin, A.A.; Krebs, H. [Ruhr-Universitaet Bochum, Institut fuer Theoretische Physik II, Bochum (Germany); Hanhart, C. [Forschungszentrum Juelich, Institut fuer Kernphysik, (Theorie) and Juelich Center for Hadron Physics, Juelich (Germany); Forschungszentrum Juelich, Institute for Advanced Simulation, Juelich (Germany); Myhrer, F. [University of South Carolina, Department of Physics and Astronomy, Columbia, SC (United States)

    2016-05-15

    The reaction NN→NNπ offers a good testing ground for chiral effective field theory at intermediate energies. It challenges our understanding of the first inelastic channel in nucleon-nucleon scattering and of the charge symmetry breaking pattern in hadronic reactions. In our previous studies, we presented a complete calculation of the pion production operator for s-wave pions up-to-and-including next-to-next-to-leading order (NNLO) in the formulation of chiral effective field theory, which includes pions, nucleons and Δ(1232) degrees of freedom. In this paper we calculate the near-threshold cross section for the pp → dπ{sup +} reaction by performing the convolution of the obtained operators with nuclear wave functions based on modern phenomenological and chiral potentials. The available chiral NN wave functions are constructed with a cutoff comparable with the momentum transfer scale inherent in pion production reactions. Hence, a significant portion of the dynamical intermediate-range physics is thereby cut off by them. On the other hand, the NNLO amplitudes evaluated with phenomenological wave functions appear to be largely independent of the NN model used and give corrections to the dominant leading-order contributions as expected from dimensional analysis. The result gives support to the counting scheme used to classify the pion production operators, which is a precondition for a reliable investigation of the chirally suppressed neutral pion production. The explicit inclusion of the Δ(1232) is found to be important but smaller than expected due to cancellations. (orig.)

  19. Magnetization switching in ferromagnets by adsorbed chiral molecules without current or external magnetic field.

    Science.gov (United States)

    Ben Dor, Oren; Yochelis, Shira; Radko, Anna; Vankayala, Kiran; Capua, Eyal; Capua, Amir; Yang, See-Hun; Baczewski, Lech Tomasz; Parkin, Stuart Stephen Papworth; Naaman, Ron; Paltiel, Yossi

    2017-02-23

    Ferromagnets are commonly magnetized by either external magnetic fields or spin polarized currents. The manipulation of magnetization by spin-current occurs through the spin-transfer-torque effect, which is applied, for example, in modern magnetoresistive random access memory. However, the current density required for the spin-transfer torque is of the order of 1 × 10(6) A·cm(-2), or about 1 × 10(25) electrons s(-1) cm(-2). This relatively high current density significantly affects the devices' structure and performance. Here we demonstrate magnetization switching of ferromagnetic thin layers that is induced solely by adsorption of chiral molecules. In this case, about 10(13) electrons per cm(2) are sufficient to induce magnetization reversal. The direction of the magnetization depends on the handedness of the adsorbed chiral molecules. Local magnetization switching is achieved by adsorbing a chiral self-assembled molecular monolayer on a gold-coated ferromagnetic layer with perpendicular magnetic anisotropy. These results present a simple low-power magnetization mechanism when operating at ambient conditions.

  20. Magnetization switching in ferromagnets by adsorbed chiral molecules without current or external magnetic field

    Science.gov (United States)

    Ben Dor, Oren; Yochelis, Shira; Radko, Anna; Vankayala, Kiran; Capua, Eyal; Capua, Amir; Yang, See-Hun; Baczewski, Lech Tomasz; Parkin, Stuart Stephen Papworth; Naaman, Ron; Paltiel, Yossi

    2017-01-01

    Ferromagnets are commonly magnetized by either external magnetic fields or spin polarized currents. The manipulation of magnetization by spin-current occurs through the spin-transfer-torque effect, which is applied, for example, in modern magnetoresistive random access memory. However, the current density required for the spin-transfer torque is of the order of 1 × 106 A·cm−2, or about 1 × 1025 electrons s−1 cm−2. This relatively high current density significantly affects the devices' structure and performance. Here we demonstrate magnetization switching of ferromagnetic thin layers that is induced solely by adsorption of chiral molecules. In this case, about 1013 electrons per cm2 are sufficient to induce magnetization reversal. The direction of the magnetization depends on the handedness of the adsorbed chiral molecules. Local magnetization switching is achieved by adsorbing a chiral self-assembled molecular monolayer on a gold-coated ferromagnetic layer with perpendicular magnetic anisotropy. These results present a simple low-power magnetization mechanism when operating at ambient conditions. PMID:28230054

  1. Chiroptical studies on supramolecular chirality of molecular aggregates.

    Science.gov (United States)

    Sato, Hisako; Yajima, Tomoko; Yamagishi, Akihiko

    2015-10-01

    The attempts of applying chiroptical spectroscopy to supramolecular chirality are reviewed with a focus on vibrational circular dichroism (VCD). Examples were taken from gels, solids, and monolayers formed by low-molecular mass weight chiral gelators. Particular attention was paid to a group of gelators with perfluoroalkyl chains. The effects of the helical conformation of the perfluoroalkyl chains on the formation of chiral architectures are reported. It is described how the conformation of a chiral gelator was determined by comparing the experimental and theoretical VCD spectra together with a model proposed for the molecular aggregation in fibrils. The results demonstrate the potential utility of the chiroptical method in analyzing organized chiral aggregates.

  2. Expanding proteomics into the analysis of chiral drugs.

    Science.gov (United States)

    Sui, Jianjun; Zhang, Jianhua; Ching, Chi Bun; Chen, Wei Ning

    2009-06-01

    The chiralities of chiral drugs have been investigated extensively with the purpose of enlightening the role of chirality in drug action. Proteomics, though in its infancy, has recently emerged as the foremost technology in drug development research, possessing the advantage of providing more useful information about an organism than genomics, as it directly addresses the level of genome products and their interactions. In this review, we will discuss the background of chiral drug investigation from which contemporary drug chirality research has emerged, the techniques involved in proteomics technology, the application of proteomics in this exciting area, and the perspectives in future applications of this field.

  3. Application of chiral thiazolidine ligands to asymmetric hydrosilation

    Institute of Scientific and Technical Information of China (English)

    李弘; 姚金水; 何炳林

    1997-01-01

    Seven chiral thiazolidines bound rhodium complexes were synthesized and their catalytic asymmetric hydrosilation properties were investigated It was found through investigation that the configuration of newly formed chiral centre C2 of substituted chiral thiazolidines prepared from L-cysteine or its esters has no effect on the final results of catalytic asymmetric hydrosilation.The direct reason for causing this phenomenon is reported by the present quantitative results for the first time:the rapid racemation of chiral center C2 of chiral thiazolidine ligands takes place under the catalysis of rhodium(Ⅰ) complex [Rh(COD)CI]2

  4. Nematic twist cell: Strong chirality induced at the surfaces

    Science.gov (United States)

    Lin, Tzu-Chieh; Nemitz, Ian R.; Pendery, Joel S.; Schubert, Christopher P. J.; Lemieux, Robert P.; Rosenblatt, Charles

    2013-04-01

    A nematic twist cell having a thickness gradient was filled with a mixture containing a configurationally achiral liquid crystal (LC) and chiral dopant. A chiral-based linear electrooptic effect was observed on application of an ac electric field. This "electroclinic effect" varied monotonically with d, changing sign at d =d0 where the chiral dopant exactly compensated the imposed twist. The results indicate that a significant chiral electrooptic effect always exists near the surfaces of a twist cell containing molecules that can be conformationally deracemized. Additionally, this approach can be used to measure the helical twisting power (HTP) of a chiral dopant in a liquid crystal.

  5. Fluctuations of Goldstone modes and the chiral transition in QCD

    CERN Document Server

    Karsch, Frithjof

    2008-01-01

    We provide evidence for the influence of thermal fluctuations of Goldstone modes on the chiral condensate at finite temperature. We show that at fixed temperature, Tchiral transition temperature this leads to a characteristic dependence of the chiral condensate on the square root of the light quark mass (m_l), which is expected for 3-dimensional models with broken O(N) symmetry. As a consequence the chiral susceptibility shows a strong quark mass dependence for all temperatures below Tc and diverges like 1/sqrt(m_l) in the chiral limit.

  6. Fabrication and characterization of three-dimensional biomimetic chiral composites.

    Science.gov (United States)

    Turner, Mark D; Schröder-Turk, Gerd E; Gu, Min

    2011-05-09

    Here we show the fabrication and characterization of a novel class of biomimetic photonic chiral composites inspired by a recent finding in butterfly wing-scales. These three-dimensional networks have cubic symmetry, are fully interconnected, have robust mechanical strength and possess chirality which can be controlled through the composition of multiple chiral networks, providing an excellent platform for developing novel chiral materials. Using direct laser writing we have fabricated different types of chiral composites that can be engineered to form novel photonic devices. We experimentally show strong circular dichroism and compare with numerical simulations to illustrate the high quality of these three-dimensional photonic structures.

  7. Chirally symmetric but confined hadrons at finite density

    CERN Document Server

    Glozman, L Ya

    2008-01-01

    At a critical finite chemical potential and low temperature QCD undergoes the chiral restoration phase transition. The folklore tradition is that simultaneously hadrons are deconfined and there appears the quark matter. We demonstrate that it is possible to have confined but chirally symmetric hadrons at a finite chemical potential and hence beyond the chiral restoration point at a finite chemical potential and low temperature there could exist a chirally symmetric matter consisting of chirally symmetric but confined hadrons. If it does happen in QCD, then the QCD phase diagram should be reconsidered with obvious implications for heavy ion programs and astrophysics.

  8. Enantiopure Ferrocene-Based Planar-Chiral Iridacycles: Stereospecific Control of Iridium-Centred Chirality.

    Science.gov (United States)

    Arthurs, Ross A; Ismail, Muhammad; Prior, Christopher C; Oganesyan, Vasily S; Horton, Peter N; Coles, Simon J; Richards, Christopher J

    2016-02-24

    Reaction of [IrCp*Cl2 ]2 with ferrocenylimines (Fc=NAr, Ar=Ph, p-MeOC6 H4 ) results in ferrocene C-H activation and the diastereoselective synthesis of half-sandwich iridacycles of relative configuration Sp *,RIr *. Extension to (S)-2-ferrocenyl-4-(1-methylethyl)oxazoline gave highly diastereoselective control over the new elements of planar chirality and metal-based pseudo-tetrahedral chirality, to give both neutral and cationic half-sandwich iridacycles of absolute configuration Sc ,Sp ,RIr . Substitution reactions proceed with retention of configuration, with the planar chirality controlling the metal-centred chirality through an iron-iridium interaction in the coordinatively unsaturated cationic intermediate.

  9. When Chiral Photons Meet Chiral Fermions: Photoinduced Anomalous Hall Effects in Weyl Semimetals

    Science.gov (United States)

    Chan, Ching-Kit; Lee, Patrick A.; Burch, Kenneth S.; Han, Jung Hoon; Ran, Ying

    2016-01-01

    The Weyl semimetal is characterized by three-dimensional linear band touching points called Weyl nodes. These nodes come in pairs with opposite chiralities. We show that the coupling of circularly polarized photons with these chiral electrons generates a Hall conductivity without any applied magnetic field in the plane orthogonal to the light propagation. This phenomenon comes about because with all three Pauli matrices exhausted to form the three-dimensional linear dispersion, the Weyl nodes cannot be gapped. Rather, the net influence of chiral photons is to shift the positions of the Weyl nodes. Interestingly, the momentum shift is tightly correlated with the chirality of the node to produce a net anomalous Hall signal. Application of our proposal to the recently discovered TaAs family of Weyl semimetals leads to an order-of-magnitude estimate of the photoinduced Hall conductivity which is within the experimentally accessible range.

  10. Peak of Chiral Susceptibility and Chiral Phase Transition in QED3

    Institute of Scientific and Technical Information of China (English)

    ZHOU Yu-Qing; YANG Yong-Hong

    2011-01-01

    A general expression for the scalar susceptibility in QEDs is given. We adopt the Dyson-Schwinger equation for the fermion propagator to solve xc within a range of the number of fermion flavors, N, in chiral symmetry breaking phase. We show that the scalar susceptibility has a peak and the corresponding N is less than the critical number of fermion flavors for chiral symmetry.%@@ A general expression for the scalar susceptibility in QED3 is given.We adopt the Dyson-Schwinger equation for the fermion propagator to solve Xc within a range of the number of fermion flavors, N, in chiral symmetry breaking phase.We show that the scalar susceptibility has a peak and the corresponding N is less than thecritical number of fermion flavors for chiral symmetry.

  11. Synthesis of a Chiral Crystal Form of MOF-5, CMOF-5, by Chiral Induction.

    Science.gov (United States)

    Zhang, Shi-Yuan; Li, Dan; Guo, Dong; Zhang, Hui; Shi, Wei; Cheng, Peng; Wojtas, Lukasz; Zaworotko, Michael J

    2015-12-16

    Chiral variants of the prototypal metal-organic framework MOF-5, Λ-CMOF-5 and Δ-CMOF-5, have been synthesized by preparing MOF-5 in the presence of L-proline or D-proline, respectively. CMOF-5 crystallizes in chiral space group P213 instead of Fm3̅m as exhibited by MOF-5. The phase purity of CMOF-5 was validated by single-crystal and powder X-ray diffraction, infrared spectroscopy, thermogravimetric analysis, N2 adsorption, microanalysis, and solid-state vibrational circular dichroism. CMOF-5 undergoes a reversible single crystal-to-single crystal phase change to MOF-5 when immersed in a variety of organic solvents, although N-methyl-2-pyrrolidone (NMP) does not induce loss of chirality. Indeed, MOF-5 undergoes chiral induction when immersed in NMP, affording racemic CMOF-5.

  12. Spintronics and chirality: spin selectivity in electron transport through chiral molecules.

    Science.gov (United States)

    Naaman, Ron; Waldeck, David H

    2015-04-01

    Recent experiments have demonstrated that the electron transmission yield through chiral molecules depends on the electron spin orientation. This phenomenon has been termed the chiral-induced spin selectivity (CISS) effect, and it provides a challenge to theory and promise for organic molecule-based spintronic devices. This article reviews recent developments in our understanding of CISS. Different theoretical models have been used to describe the effect; however, they all presume an unusually large spin-orbit coupling in chiral molecules for the effect to display the magnitudes seen in experiments. A simplified model for an electron's transport through a chiral potential suggests that these large couplings can be manifested. Techniques for measuring spin-selective electron transport through molecules are overviewed, and some examples of recent experiments are described. Finally, we present results obtained by studying several systems, and we describe the possible application of the CISS effect for memory devices.

  13. Intelligent Chiral Sensing Based on Supramolecular and Interfacial Concepts

    Directory of Open Access Journals (Sweden)

    Hironori Izawa

    2010-07-01

    Full Text Available Of the known intelligently-operating systems, the majority can undoubtedly be classed as being of biological origin. One of the notable differences between biological and artificial systems is the important fact that biological materials consist mostly of chiral molecules. While most biochemical processes routinely discriminate chiral molecules, differentiation between chiral molecules in artificial systems is currently one of the challenging subjects in the field of molecular recognition. Therefore, one of the important challenges for intelligent man-made sensors is to prepare a sensing system that can discriminate chiral molecules. Because intermolecular interactions and detection at surfaces are respectively parts of supramolecular chemistry and interfacial science, chiral sensing based on supramolecular and interfacial concepts is a significant topic. In this review, we briefly summarize recent advances in these fields, including supramolecular hosts for color detection on chiral sensing, indicator-displacement assays, kinetic resolution in supramolecular reactions with analyses by mass spectrometry, use of chiral shape-defined polymers, such as dynamic helical polymers, molecular imprinting, thin films on surfaces of devices such as QCM, functional electrodes, FET, and SPR, the combined technique of magnetic resonance imaging and immunoassay, and chiral detection using scanning tunneling microscopy and cantilever technology. In addition, we will discuss novel concepts in recent research including the use of achiral reagents for chiral sensing with NMR, and mechanical control of chiral sensing. The importance of integration of chiral sensing systems with rapidly developing nanotechnology and nanomaterials is also emphasized.

  14. Electrochemical impedance based chiral analysis of anti-ascorbutic drug: l-Ascorbic acid and d-ascorbic acid using C-dots decorated conductive polymer nano-composite electrode.

    Science.gov (United States)

    Pandey, Indu; Kant, Rama

    2016-03-15

    Clinical manifestations owing to l-ascorbic acid for scurvy as comparison to d-ascorbic acid and challenges of chiral purity are overcome by using chiral selective conductive polymer nanocomposite which mimics antibodies and enzymes. A novel chiral selective imprinted polyaniline-ferrocene-sulfonic acid film has been electrochemically fabricated on C-dots modified pencil graphite electrode. The performance of the obtained l-ascorbic acid or d-ascorbic acid chiral selective sensor was investigated by electrochemical impedance spectroscopy, cyclic and differential pulse voltammetry. The surface characteristics of the C-dots, chiral sensor before and after the de-doping of chiral d- and l-ascorbic acid were characterized by scanning electron microscopy, Raman spectroscopy and X-ray diffraction spectroscopy. Excellent recognition results were obtained by difference in electron transfer resistance. The proposed chiral sensor is capable of measuring d-ascorbic acid or l-ascorbic acid in aqueous as well as in real and commercial samples within the range of 0.020-0.187 nM and 0.003-0.232 nM with detection limit of 0.00073 nM and 0.00016 nM, respectively. The proposed method has also been examined for the chiral selective recognition of ascorbic acid isomers (d- and l-) quantitatively, in complicated matrices of real samples.

  15. Chiral-field microwave antennas (Chiral microwave near fields for far-field radiation)

    CERN Document Server

    Kamenetskii, E O; Shavit, R

    2015-01-01

    In a single-element structure we obtain a radiation pattern with a squint due to chiral microwave near fields originated from a magnetostatic-mode ferrite disk. At the magnetostatic resonances, one has strong subwavelength localization of energy of microwave radiation. Magnetostatic oscillations in a thin ferrite disk are characterized by unique topological properties: the Poynting-vector vortices and the field helicity. The chiral-topology near fields allow obtaining unique phase structure distribution for far-field microwave radiation.

  16. Proline Based Chiral Ionic Liquids for Enantioselective Michael Reaction

    Directory of Open Access Journals (Sweden)

    Kaoru Nobuoka

    2014-01-01

    Full Text Available Chiral ionic liquids, starting from (S-proline, have been prepared and evaluated the ability of a chiral catalyst. In Michael reaction of trans-β-nitrostyrene and cyclohexanone, all the reactions were carried out under homogeneous conditions without any solvent except for excess cyclohexanone. The chiral ionic liquid catalyst with the positive charge delocalized bulky pyrrolidinium cation shows excellent yields (up to 92%, diastereoselectivities (syn/anti = 96/4, and enantioselectivities (up to 95% ee and could be reused at least three times without any loss of its catalytic activity. Such results demonstrated a promising new approach for green and economic chiral synthesis by using the chiral ionic liquids as a chiral catalyst and a chiral medium.

  17. Cooperative expression of atomic chirality in inorganic nanostructures

    Science.gov (United States)

    Wang, Peng-Peng; Yu, Shang-Jie; Govorov, Alexander O.; Ouyang, Min

    2017-02-01

    Cooperative chirality phenomena extensively exist in biomolecular and organic systems via intra- and inter-molecular interactions, but study of inorganic materials has been lacking. Here we report, experimentally and theoretically, cooperative chirality in colloidal cinnabar mercury sulfide nanocrystals that originates from chirality interplay between the crystallographic lattice and geometric morphology at different length scales. A two-step synthetic scheme is developed to allow control of critical parameters of these two types of handedness, resulting in different chiral interplays expressed as observables through materials engineering. Furthermore, we adopt an electromagnetic model with the finite element method to elucidate cooperative chirality in inorganic systems, showing excellent agreement with experimental results. Our study enables an emerging class of nanostructures with tailored cooperative chirality that is vital for fundamental understanding of nanoscale chirality as well as technology applications based on new chiroptical building blocks.

  18. Chirality detection of enantiomers using twisted optical metamaterials

    Science.gov (United States)

    Zhao, Yang; Askarpour, Amir N.; Sun, Liuyang; Shi, Jinwei; Li, Xiaoqin; Alù, Andrea

    2017-01-01

    Many naturally occurring biomolecules, such as amino acids, sugars and nucleotides, are inherently chiral. Enantiomers, a pair of chiral isomers with opposite handedness, often exhibit similar physical and chemical properties due to their identical functional groups and composition, yet show different toxicity to cells. Detecting enantiomers in small quantities has an essential role in drug development to eliminate their unwanted side effects. Here we exploit strong chiral interactions with plasmonic metamaterials with specifically designed optical response to sense chiral molecules down to zeptomole levels, several orders of magnitude smaller than what is typically detectable with conventional circular dichroism spectroscopy. In particular, the measured spectra reveal opposite signs in the spectral regime directly associated with different chiral responses, providing a way to univocally assess molecular chirality. Our work introduces an ultrathin, planarized nanophotonic interface to sense chiral molecules with inherently weak circular dichroism at visible and near-infrared frequencies.

  19. Symmetries of hadrons after unbreaking the chiral symmetry

    CERN Document Server

    Glozman, L Ya; Schröck, M

    2012-01-01

    We study hadron correlators upon artificial restoration of the spontaneously broken chiral symmetry. In a dynamical lattice simulation we remove the lowest lying eigenmodes of the Dirac operator from the valence quark propagators and study evolution of the hadron masses obtained. All mesons and baryons in our study, except for a pion, survive unbreaking the chiral symmetry and their exponential decay signals become essentially better. From the analysis of the observed spectroscopic patterns we conclude that confinement still persists while the chiral symmetry is restored. All hadrons fall into different chiral multiplets. The broken U(1)_A symmetry does not get restored upon unbreaking the chiral symmetry. We also observe signals of some higher symmetry that includes chiral symmetry as a subgroup. Finally, from comparison of the \\Delta - N splitting before and after unbreaking of the chiral symmetry we conclude that both the color-magnetic and the flavor-spin quark-quark interactions are of equal importance.

  20. Chiral spiral induced by a strong magnetic field

    Directory of Open Access Journals (Sweden)

    Abuki Hiroaki

    2016-01-01

    Full Text Available We study the modification of the chiral phase structure of QCD due to an external magnetic field. We first demonstrate how the effect of magnetic field can systematically be incorporated into a generalized Ginzburg-Landau framework. We then analyze the phase structure in the vicinity of the chiral critical point. In the chiral limit, the effect is found to be so drastic that it brings a “continent” of chiral spiral in the phase diagram, by which the chiral tricritical point is totally washed out. This is the case no matter how small the intensity of magnetic field is. On the other hand, the current quark mass protects the chiral critical point from a weak magnetic field. However, the critical point will eventually be covered by the chiral spiral phase as the magnetic field grows.

  1. Chiral phase transition in QED3 at finite temperature

    Science.gov (United States)

    Yin, Pei-Lin; Xiao, Hai-Xiao; Wei, Wei; Feng, Hong-Tao; Zong, Hong-Shi

    2016-12-01

    In the framework of Dyson-Schwinger equations, we employ two kinds of criteria (one kind is the chiral condensate, the other kind is thermodynamic quantities, such as the pressure, the entropy, and the specific heat) to investigate the nature of chiral phase transitions in QED3 for different fermion flavors. It is found that the chiral phase transitions in QED3 for different fermion flavors are all typical second-order phase transitions; the critical temperature and order of the chiral phase transition obtained from the chiral condensate and susceptibility are the same with that obtained by the thermodynamic quantities, which means that they are equivalent in describing the chiral phase transition; the critical temperature decreases as the number of fermion flavors increases and there is a boundary that separates the Tc-Nf plane into chiral symmetry breaking and restoration regions.

  2. Chiral Orbifold Construction Of Field Theories With Extra Dimensions

    CERN Document Server

    Hailu, G

    2003-01-01

    We build higher dimensional field theories which have chiral fermion zero-modes on orbifolds. We show that orbifold boundary conditions and scalar vacuum expectation values interplay to produce chiral fermions localized on fat three branes. We develop a scheme for computing field propagators in higher dimensional theories obeying chiral orbifold boundary conditions. Using this scheme we compute the loop corrections to an effective field theory in five dimensions. We find that the renormalization group running of the higher dimensional bulk theory leads to a running of the four dimensional brane couplings. We generalize an argument to verify that the chiral anomaly that arises in these chiral orbifold theories is entirely confined on and uniformly distributed over the fixed points of the orbifold, independent of the shape of the chiral zero-modes. We construct a setup in which a scalar field with appropriate profile in the extra dimension is used to address the hierarchy problem and also localize both chiral f...

  3. Synthesis of Chiral Building Blocks for Use in Drug Discovery

    Directory of Open Access Journals (Sweden)

    Rustum S. Boyce

    2004-05-01

    Full Text Available In the past decade there has been a significant growth in the sales of pharmaceutical drugs worldwide, but more importantly there has been a dramatic growth in the sales of single enantiomer drugs. The pharmaceutical industry has a rising demand for chiral intermediates and research reagents because of the continuing imperative to improve drug efficacy. This in turn impacts on researchers involved in preclinical discovery work. Besides traditional chiral pool and resolution of racemates as sources of chiral building blocks, many new synthetic methods including a great variety of catalytic reactions have been developed which facilitate the production of complex chiral drug candidates for clinical trials. The most ambitious technique is to synthesise homochiral compounds from non-chiral starting materials using chiral metal catalysts and related chemistry. Examples of the synthesis of chiral building blocks from achiral materials utilizing asymmetric hydrogenation and asymmetric epoxidation are presented.

  4. A Non—linear Non—ideal Model of Simulated Moving Bed Chromatography for Chiral Separations

    Institute of Scientific and Technical Information of China (English)

    卢建刚

    2003-01-01

    A non-linear non-ideal model,taking into account non-linear competitive isotherms,axial disperison,film mass transfer,intraparticle diffusion,and port periodic switching,was developed to simulate the dynamics of simulated moving bed chromatography(SMBC),The model equations were solved by a new efficient numerical technique of orthogonal collocation on finite elements with periodical movement of conceantration vector,The simulated SMBC performance is in accordance with the experimental results reported in the literature for separation of 1,1''''''''-bi-2-naphtol enantiomers using SMBC,This model is useful for design,operation ,optimization and scale-up of non-linear SMBC for chiral separations with significant non-ideal effects,especially for high solute concentration and small intraparticle diffusion coefficient or large chiral stationary phase particle.

  5. First Measurement of Chiral Dynamics in $\\pi^-\\gamma \\to \\pi^-\\pi^-\\pi^+$

    CERN Document Server

    Adolph, C; Alexakhin, V Yu; Alexandrov, Yu; Alexeev, G D; Amoroso, A; Antonov, A A; Austregesilo, A; Badelek, B; Balestra, F; Barth, J; Baum, G; Bedfer, Y; Bernhard, J; Bertini, R; Bettinelli, M; Bicker, K A; Birsa, R; Bisplinghoff, J; Bordalo, P; Bradamante, F; Braun, C; Bravar, A; Bressan, A; Burtin, E; Chaberny, D; Chiosso, M; Chung, S U; Cicuttin, A; Crespo, M L; Dalla Torre, S; Das, S; Dasgupta, S S; Denisov, O Yu; Dhara, L; Donskov, S V; Doshita, N; Duic, V; Dunnweber, W; Dziewiecki, M; Efremov, A; Elia, C; Eversheim, P D; Eyrich, W; Faessler, M; Ferrero, A; Filin, A; Finger, M; Finger, M; Fischer, H; Franco, C; du Fresne von Hohenesche, N; Friedrich, J M; Garfagnini, R; Gautheron, F; Gavrichtchouk, O P; Gazda, R; Gerassimov, S; Geyer, R; Giorgi, M; Gnesi, I; Gobbo, B; Goertz, S; Grabmuller, S; Grasso, A; Grube, B; Gushterski, R; Guskov, A; Haas, F; von Harrach, D; Hasegawa, T; Heinsius, F H; Herrmann, F; Hess, C; Hinterberger, F; Horikawa, N; Hoppner, Ch; d'Hose, N; Huber, S; Ishimoto, S; Ivanov, O; Ivanshin, Yu; Iwata, T; Jahn, R; Jasinski, P; Jegou, G; Joosten, R; Kabuss, E; Kang, D; Ketzer, B; Khaustov, G V; Khokhlov, Yu A; Kisselev, Yu; Klein, F; Klimaszewski, K; Koblitz, S; Koivuniemi, J H; Kolosov, V N; Kondo, K; Konigsmann, K; Konorov, I; Konstantinov, V F; Korzenev, A; Kotzinian, A M; Kouznetsov, O; Kramer, M; Kroumchtein, Z V; Kunne, F; Kurek, K; Lauser, L; Lednev, A A; Lehmann, A; Levorato, S; Lichtenstadt, J; Maggiora, A; Magnon, A; Makke, N; Mallot, G K; Mann, A; Marchand, C; Martin, A; Marzec, J; Massmann, F; Matsuda, T; Meyer, W; Michigami, T; Mikhailov, Yu V; Moinester, M A; Morreale, A; Mutter, A; Nagaytsev, A; Nagel, T; Nerling, F; Neubert, S; Neyret, D; Nikolaenko, V I; Nowak, W D; Nunes, A S; Olshevsky, A G; Ostrick, M; Padee, A; Panknin, R; Panzieri, D; Parsamyan, B; Paul, S; Perevalova, E; Pesaro, G; Peshekhonov, D V; Piragino, G; Platchkov, S; Pochodzalla, J; Polak, J; Polyakov, V A; Pontecorvo, G; Pretz, J; Quintans, C; Rajotte, J F; Ramos, S; Rapatsky, V; Reicherz, G; Richter, A; Rocco, E; Rondio, E; Rossiyskaya, N S; Ryabchikov, D I; Samoylenko, V D; Sandacz, A; Sapozhnikov, M G; Sarkar, S; Savin, I A; Sbrizzai, G; Schiavon, P; Schill, C; Schluter, T; Schmitt, L; Schonning, K; Schopferer, S; Schroder, W; Shevchenko, O Yu; Siebert, H W; Silva, L; Sinha, L; Sissakian, A N; Slunecka, M; Smirnov, G I; Sosio, S; Sozzi, F; Srnka, A; Stolarski, M; Sulc, M; Sulej, R; Sznajder, P; Takekawa, S; Ter Wolbeek, J; Tessaro, S; Tessarotto, F; Teufel, A; Tkatchev, L G; Uhl, S; Uman, I; Vandenbroucke, M; Virius, M; Vlassov, N V; Windmolders, R; Wislicki, W; Wollny, H; Zaremba, K; Zavertyaev, M; Zemlyanichkina, E; Ziembicki, M; Zhuravlev, N; Zvyagin, A

    2012-01-01

    The COMPASS collaboration at CERN has investigated the $\\pi^-\\gamma \\to \\pi^-\\pi^-\\pi^+$ reaction at center-of-momentum energy below five pion masses, $\\sqrt{s} \\lt 5m_\\pi$ , embedded in the Primakoff reaction of 190 GeV pions impinging on a lead target. Exchange of quasi-real photons is selected by isolating the sharp Coulomb peak observed at smallest momentum transfers, $t' \\lt 0.001 GeV^2/c^2$. Using partial-wave analysis techniques, the scattering intensity of Coulomb production described in terms of chiral dynamics and its dependence on the 3pi-invariant mass $m_{3\\pi} = \\sqrt{s}$ were extracted. The absolute cross section was determined in seven bins of $\\sqrt{s}$ with an overall precision of 20%. At leading order, the result is found to be in good agreement with the prediction of chiral perturbation theory over the whole energy range investigated.

  6. Optical and Electrical Properties of Single-walled Carbon Nanotubes with Known Chiralities

    Science.gov (United States)

    Zhang, Zhengyi

    Carbon nanotube (CNT) is a hollow structure consisted by one-atom-thick sheet of carbon atoms, which can be considered as a rolled-up graphene sheet. The diameter and rolling angle (chirality) uniquely determines its electronic structure. Over two decades of study, due to the difficulty of synthesizing clean individual CNTs and the limitation of accurate chirality characterization, there are still unveiled questions towards the intrinsic properties of this 1-D material at single molecular level. In this thesis, I will discuss the approaches of fabricating chirality assigned CNT device and the experimental results of its optical and electrical properties. In the first part, I describe using 'fast heating' chemical vapor deposition (CVD) method to achieve the high quality suspended CNT growth. Combining Rayleigh and Raman spectroscopy, I demonstrate the accurate assignment of chirality for each suspended individual CNT. With the ability of chirality identification, a series of optical and electrical experiments were conducted on the selected CNTs of interest. In the following part, I first discuss the probe of many-body effect in a semiconducting CNT by observing the elastic scattering (Rayleigh spectra) with electrostatic gating. We found the dominant short-range interaction is reduced to 85% of its intrinsic strength for doping level of rho=0.4e/nm, demonstrating the possible control of sub-band exciton resonance frequency without rely on Pauli-blocking effect in CNTs. In order to study the substrate effect in electrical transport of CNTs, I improved the transfer technique to accurately place individual CNT on a specific substrate. With this technique, I've achieved transferring individual CNT on 20mum thin layer of hexagonal-boron nitride (h-BN) substrate with a +/- 5mum error. The low field electrical transport studies were conducted on both metallic and semiconducting CNTs with known chiralities on h-BN. Temperature dependent measurement shows the resistivity

  7. Preparation of Chiral 1,4-Phenylene-silicas via Chiral Low-molecular-weight Amphiphiles

    Institute of Scientific and Technical Information of China (English)

    XIAO Min; LIU Xiao-juan; HU Kai; WU Li-min; LI Yi; LI Bao-zong; YANG Yong-gang

    2012-01-01

    Chiral organic-inorganic hybrid silicas can be prepared via the self-assemblies of chiral surfactants and gelators as templates.However,the relationship between the chirality of the hybrid silica and the structure of the surfactant/gelator has not been systemically studied.Herein,a series of chiral low-molecular-weight amphiphiles(LMWAs) derived from L-valine was synthesized.Their alkyl chains were n-butadecyl,n-hexadecyl and n-octadecyl,respectively.They can form viscous liquids in pure water,and physical gels in tetrahydrofuran,cyclohexanone,acetonitrile,acetone,chlorobenzene and nitrobenzenc.Chiral 1,4-phenylene-silicas were prepared via the self-assemblies of these LMWAs as templates.With increasing the alkyl chain length,the 1,4-phenylene-silicas changed from short mesoporous nanorods to long nanotubcs. The circular dichroism spectra of the 1,4-phenylene-silicas indicated that the long nanotubes exhibit the strongest chirality.

  8. Fermion Determinant with Dynamical Chiral Symmetry Breaking

    Institute of Scientific and Technical Information of China (English)

    LU Qin; YANG Hua; WANG Qing

    2002-01-01

    One-loop fermion determinant is discussed for the case in which the dynamical chiral symmetry breakingcaused by momentum-dependent fermion self-energy ∑(p2) takes place. The obtained series generalizes the heat kernelexpansion for hard fermion mass.

  9. Finite Density QCD in the Chiral Limit

    CERN Document Server

    Aloisio, R; Di Carlo, G; Galante, A; Grillo, A F

    1998-01-01

    We present the first results of an exact simulation of full QCD at finite density in the chiral limit. We have used a MFA (Microcanonical Fermionic Average) inspired approach for the reconstruction of the Grand Canonical Partition Function of the theory; using the fugacity expansion of the fermionic determinant we are able to move continuously in the ($\\beta -\\mu$) plane with $m=0$.

  10. Field-enlarging transformations and chiral theories

    CERN Document Server

    Sladkowski, J

    1995-01-01

    A field-enlarging transformation in the chiral electrodynamics is performed. This introduces an additional gauge symmetry to the model that is unitary and anomaly-free and allows for comparison of different models discussed in the literature. The problem of superfluous degrees of freedom and their influence on quantization is discussed. Several "mysteries" are explained from this point of view.

  11. Chiral damping of magnetic domain walls

    Science.gov (United States)

    Jué, Emilie; Safeer, C. K.; Drouard, Marc; Lopez, Alexandre; Balint, Paul; Buda-Prejbeanu, Liliana; Boulle, Olivier; Auffret, Stephane; Schuhl, Alain; Manchon, Aurelien; Miron, Ioan Mihai; Gaudin, Gilles

    2016-03-01

    Structural symmetry breaking in magnetic materials is responsible for the existence of multiferroics, current-induced spin-orbit torques and some topological magnetic structures. In this Letter we report that the structural inversion asymmetry (SIA) gives rise to a chiral damping mechanism, which is evidenced by measuring the field-driven domain-wall (DW) motion in perpendicularly magnetized asymmetric Pt/Co/Pt trilayers. The DW dynamics associated with the chiral damping and those with Dzyaloshinskii-Moriya interaction (DMI) exhibit identical spatial symmetry. However, both scenarios are differentiated by their time reversal properties: whereas DMI is a conservative effect that can be modelled by an effective field, the chiral damping is purely dissipative and has no influence on the equilibrium magnetic texture. When the DW motion is modulated by an in-plane magnetic field, it reveals the structure of the internal fields experienced by the DWs, allowing one to distinguish the physical mechanism. The chiral damping enriches the spectrum of physical phenomena engendered by the SIA, and is essential for conceiving DW and skyrmion devices owing to its coexistence with DMI (ref. ).

  12. On the Chiral imbalance and Weibel Instabilities

    CERN Document Server

    Kumar, Avdhesh; Kaw, Predhiman K

    2016-01-01

    We study the chiral-imbalance and the Weibel instabilities in presence of the quantum anomaly using the Berry-curvature modified kinetic equation. We argue that in many realistic situations, e.g. relativistic heavy-ion collisions, both the instabilities can occur simultaneously. The Weibel instability depends on the momentum anisotropy parameter $\\xi$ and the angle ($\\theta_n$) between the propagation vector and the anisotropy direction. It has maximum growth rate at $\\theta_n=0$ while $\\theta_n=\\pi/2$ corresponds to a damping. On the other hand the pure chiral-imbalance instability occurs in an isotropic plasma and depends on difference between the chiral chemical potentials of right and left-handed particles. It is shown that when $\\theta_n=0$, only for a very small values of the anisotropic parameter $\\xi\\sim \\xi_c$, growth rates of the both instabilities are comparable. For the cases $\\xi_c<\\xi\\ll1$, $\\xi\\approx 1$ or $\\xi \\geq 1$ at $\\theta_n=0$, the Weibel modes dominate over the chiral-imbalance ins...

  13. Chiral thiols. Synthesis and enantiomeric excess determination

    NARCIS (Netherlands)

    Strijtveen, Bernardus Wilhelmus Maria

    1987-01-01

    Chiral thiols are a class of chira compounds, which is gaining mone and nore attention the last decenniun. Especially α-mercaptocarboxylic acids are frequently found as a structunal unit in (biologically) important products. As a consequence, many synthetic analoga or derivatives of these natural pr

  14. Leading chiral logarithms for the nucleon mass

    Energy Technology Data Exchange (ETDEWEB)

    Vladimirov, Alexey A.; Bijnens, Johan [Department of Astronomy and Theoretical Physics, Lund University, Sölvegatan 14A, SE 223 62 Lund (Sweden)

    2016-01-22

    We give a short introduction to the calculation of the leading chiral logarithms, and present the results of the recent evaluation of the LLog series for the nucleon mass within the heavy baryon theory. The presented results are the first example of LLog calculation in the nucleon ChPT. We also discuss some regularities observed in the leading logarithmical series for nucleon mass.

  15. Chiral symmetry breaking, instantons, and monopoles

    CERN Document Server

    Di Giacomo, Adriano

    2015-01-01

    The purpose of this study is to show that monopoles induce the chiral symmetry breaking. In order to indicate the evidence, we add one pair of monopoles with magnetic charges to the quenched SU(3) configurations by a monopole creation operator, and investigate the propaties of the chiral symmetry breaking using the Overlap fermion. We show that instantons are created by the monopoles. The pseudoscalar meson mass and decay constant are computed from the correlation functions, and the renormalization constant $Z_{S}$ is determined by the non perturbative method. The renormalization group invariant chiral condensate in $\\overline{\\mbox{MS}}$-scheme at 2 [GeV] is evaluated by the Gell-Mann-Oakes-Renner formula, and the random matrix theory. Finally, we estimate the renormalization group invariant quark masses $\\bar{m} = (m_{u} + m_{d})/2$, and $m_{s}$ in $\\overline{\\mbox{MS}}$-scheme at 2 [GeV]. The preliminary results indicate that the chiral condensate decreases and the quark masses become slightly heavy by inc...

  16. Anomalous Hall Effect for chiral fermions

    CERN Document Server

    Zhang, P -M

    2014-01-01

    Semiclassical chiral fermions manifest the anomalous spin-Hall effect: when put into a pure electric field, they suffer a side jump, analogous to what happens to their massive counterparts in non-commutative mechanics. The transverse shift is consistent with the conservation of the angular momentum. In a pure magnetic field a cork-screw-like, spiraling motion is found.

  17. On chiral differential operators over homogeneous spaces

    Directory of Open Access Journals (Sweden)

    Vassily Gorbounov

    2001-01-01

    Full Text Available We give a classification and construction of chiral algebras of differential operators over semisimple algebraic groups G and over homogeneous spaces G/N and G/P where N is a nilpotent and P a parabolic subgroup.

  18. Wave propagation retrieval method for chiral metamaterials

    DEFF Research Database (Denmark)

    Andryieuski, Andrei; Malureanu, Radu; Lavrinenko, Andrei

    2010-01-01

    In this paper we present the wave propagation method for the retrieving of effective properties of media with circularly polarized eigenwaves, in particularly for chiral metamaterials. The method is applied for thick slabs and provides bulk effective parameters. Its strong sides are the absence...

  19. Separation of Chiral Active Pharmaceutical Ingredients

    DEFF Research Database (Denmark)

    Chaaban, Joussef Hussein

    is regarded as a first step towards a fully continuous PC process. The current knowledge of the importance of crystallization processes in the pharmaceutical industry and the complex thermodynamic and kinetic phenomena accompanied with the separation of chiral compounds are addressed. The experimental work...

  20. Orientifold Planar Equivalence: The Chiral Condensate

    DEFF Research Database (Denmark)

    Armoni, Adi; Lucini, Biagio; Patella, Agostino

    2008-01-01

    The recently introduced orientifold planar equivalence is a promising tool for solving non-perturbative problems in QCD. One of the predictions of orientifold planar equivalence is that the chiral condensates of a theory with $N_f$ flavours of Dirac fermions in the symmetric (or antisymmetric...

  1. From Ostwald Ripening to Single Chirality

    NARCIS (Netherlands)

    Noorduin, Wim L.; Vlieg, Elias; Kellogg, Richard M.; Kaptein, Bernard

    2009-01-01

    A century ago Wilhelm Ostwald received the Nobel Prize for Chemistry. Although Ostwald was never significantly involved with the phenomenon of chirality, one of his discoveries, Ostwald ripening, is thought to be involved in a recently discovered method in which grinding-induced attrition is used to

  2. Chiral superfields in N = 2 supergravity

    NARCIS (Netherlands)

    Roo, M. de; Holten, J.W. van; Wit, B. de; Proeyen, A. Van

    1980-01-01

    The transformation laws of chiral (scalar) superfields with arbitrary Weyl weight w are determined for the U(2) superconformal theory. A superconformally invariant density is given for fields with w = 2. For w = 1 it is possible to have smaller irreducible multiplets. The full restriction upon which

  3. Chiral Block Copolymer Structures for Metamaterial Applications

    Science.gov (United States)

    2015-01-27

    MONITOR’S REPORT NUMBER(S) AOARD-114078 12. DISTRIBUTION/AVAILABILITY STATEMENT Distribution A: Approved for public release. Distribtion is...researchers focused o synthesis and processing, morphology and physical characterization of chiral block copolymer (BCP) materials. Such materials a...developed a platform process technology that can fabricate novel netwo morphologies from initial bicontinuous cubic phases through supergroup/subgroup

  4. The Many Uses of Chiral Effective Theories

    NARCIS (Netherlands)

    Pallante, Elisabetta

    2008-01-01

    I review basic concepts of chiral effective field theories guided by an historical perspective: from the first ideas to the merging with other effective frameworks, and to the interplay with lattice field theory. The impact of recent theoretical developments on phenomenological predictions is review

  5. Electroweak Chiral Lagrangian for Neutral Higgs Boson

    Institute of Scientific and Technical Information of China (English)

    WANG Shun-Zhi; WANG Qing

    2008-01-01

    A neutral Higgs boson is added into the traditional electroweak chiral Lagrangian by writing down all possible high dimension operators. The matter part of the Lagrangian is investigated in detail. We find that if Higgs field dependence of Yukawa couplings can be factorized out, there will be no flavour changing neutral couplings; neutral Higgs can induce coupling between light and heavy neutrinos.

  6. Magnetic properties in the inhomogeneous chiral phase

    CERN Document Server

    Yoshiike, Ryo; Tatsumi, Toshitaka

    2016-01-01

    We investigate the magnetic properties of quark matter in the inhomogeneous chiral phase, where both scalar and pseudoscalar condensates spatially modulate. The energy spectrum of the lowest Landau level becomes asymmetric about zero in the external magnetic field, and gives rise to the remarkably magnetic properties: quark matter has a spontaneous magnetization, while the magnetic susceptibility does not diverge on the critical point.

  7. Chiral interpolation in a finite volume

    CERN Document Server

    Fukaya, H; Hashimoto, S; Kaneko, T; Matsufuru, H; Noaki, J; Onogi, T; Yamada, N

    2011-01-01

    A simulation of lattice QCD at (or even below) the physical pion mass is feasible on a small lattice size of \\sim 2 fm. The results are, however, subject to large finite volume effects. In order to precisely understand the chiral behavior in a finite volume, we develop a new computational scheme to interpolate the conventional epsilon and p regimes within chiral perturbation theory. In this new scheme, we calculate the two-point function in the pseudoscalar channel, which is described by a set of Bessel functions in an infra-red finite way as in the epsilon regime, while chiral logarithmic effects are kept manifest as in the p regime. The new ChPT formula is compared to our 2+1- flavor lattice QCD data near the physical up and down quark mass, mud \\sim 3 MeV on an L \\sim 1.8 fm lattice. We extract the pion mass = 99(4) MeV, from which we attempt a chiral "interpolation" of the observables to the physical point.

  8. ISOSPIN BREAKING AND THE CHIRAL CONDENSATE.

    Energy Technology Data Exchange (ETDEWEB)

    CREUTZ, M.

    2005-07-25

    With two degenerate quarks, the chiral condensate exhibits a jump as the quark masses pass through zero. I discuss how this single transition splits into two Ising like transitions when the quarks are made non-degenerate. The order parameter is the expectation of the neutral pion field. The transitions represent long distance coherent phenomena occurring without the Dirac operator having vanishingly small eigenvalues.

  9. Chiral anomaly and transport in Weyl metals

    Science.gov (United States)

    Burkov, A. A.

    2015-03-01

    We present an overview of our recent work on transport phenomena in Weyl metals, which may be connected to their nontrivial topological properties, particularly to chiral anomaly. We argue that there are two basic phenomena, which are related to chiral anomaly in Weyl metals: anomalous Hall effect (AHE) and chiral magnetic effect (CME). While AHE is in principle present in any ferromagnetic metal, we demonstrate that a magnetic Weyl metal is distinguished from an ordinary ferromagnetic metal by the absence of the extrinsic and the Fermi surface part of the intrinsic contributions to the AHE, as long as the Fermi energy is sufficiently close to the Weyl nodes. The AHE in a Weyl metal is thus shown to be a purely intrinsic, universal property, fully determined by the location of the Weyl nodes in the first Brillouin zone. In other words, a ferromagnetic Weyl metal may be thought of as the only example of a ferromagnetic metal with a purely intrinsic AHE. We further develop a fully microscopic theory of diffusive magnetotransport in Weyl metals. We derive coupled diffusion equations for the total and axial (i.e. node-antisymmetric) charge densities and show that chiral anomaly manifests as a magnetic-field-induced coupling between them. We demonstrate that an experimentally-observable consequence of CME in magnetotransport in Weyl metals is a quadratic negative magnetoresistance, which will dominate all other contributions to magnetoresistance under certain conditions and may be regarded as a smoking-gun transport characteristic, unique to Weyl metals.

  10. Local topological and chiral properties of QCD

    CERN Document Server

    De Forcrand, Philippe; Laermann, E; Lagaë, J F; Pérez-Garcia, M; Stamatescu, I O; Forcrand, Ph. de

    1999-01-01

    To elucidate the role played by instantons in chiral symmetry breaking, we explore their properties in full QCD, around the critical temperature. We study in particular spatial correlations between low-lying Dirac eigenmodes and instantons. Our measurements are compared with the predictions of instanton-based models.

  11. Chiral damping of magnetic domain walls

    KAUST Repository

    Jué, Emilie

    2015-12-21

    Structural symmetry breaking in magnetic materials is responsible for the existence of multiferroics1, current-induced spin–orbit torques2, 3, 4, 5, 6, 7 and some topological magnetic structures8, 9, 10, 11, 12. In this Letter we report that the structural inversion asymmetry (SIA) gives rise to a chiral damping mechanism, which is evidenced by measuring the field-driven domain-wall (DW) motion in perpendicularly magnetized asymmetric Pt/Co/Pt trilayers. The DW dynamics associated with the chiral damping and those with Dzyaloshinskii–Moriya interaction (DMI) exhibit identical spatial symmetry13, 14, 15, 16, 17, 18, 19. However, both scenarios are differentiated by their time reversal properties: whereas DMI is a conservative effect that can be modelled by an effective field, the chiral damping is purely dissipative and has no influence on the equilibrium magnetic texture. When the DW motion is modulated by an in-plane magnetic field, it reveals the structure of the internal fields experienced by the DWs, allowing one to distinguish the physical mechanism. The chiral damping enriches the spectrum of physical phenomena engendered by the SIA, and is essential for conceiving DW and skyrmion devices owing to its coexistence with DMI (ref. 20).

  12. Chiral Corrections to Vector Meson Decay Constants

    CERN Document Server

    Bijnens, J; Talavera, P; Bijnens, Johan; Gosdzinsky, Peter; Talavera, Pere

    1998-01-01

    We calculate the leading quark mass corrections of order $m_q\\log(m_q)$, $m_q$ and $m_q^{3/2}$ to the vector meson decay constants within Heavy Vector Meson Chiral Perturbation Theory. We discuss the issue of electromagnetic gauge invariance and the heavy mass expansion. Reasonably good fits to the observed decay constants are obtained.

  13. Baryon form factors in chiral perturbation theory

    CERN Document Server

    Kubis, B; Kubis, Bastian; Meissner, Ulf-G.

    2001-01-01

    We analyze the electromagnetic form factors of the ground state baryon octet to fourth order in relativistic baryon chiral perturbation theory. Predictions for the \\Sigma^- charge radius and the \\Lambda-\\Sigma^0 transition moment are found to be in excellent agreement with the available experimental information. Furthermore, the convergence behavior of the hyperon charge radii is shown to be more than satisfactory.

  14. Chiral Thermodynamics in a finite box

    CERN Document Server

    Juričić, Ana

    2016-01-01

    Finite-volume modifications of the two-flavor chiral phase diagram are investigated within an effective quark-meson model in various mean-field approximations. The role of vacuum fluctuations and boundary conditions, their influence on higher cumulants and signatures of a possible pseudo-critical endpoint are amplified with smaller volumes.

  15. The Chiral Bilayer Effect Stabilizes Micellar Fibers

    NARCIS (Netherlands)

    Fuhrhop, Jürgen-Hinrich; Schnieder, Peter; Rosenberg, Jörg; Boekema, Egbert

    1987-01-01

    Dihelical fibers several micrometers in length and gels were obtained by spontaneous aggregation of octyl L- and D-gluconamides. The single strands have the thickness of a bimolecular layer. No fibers are formed from the racemate. The tendency of the chiral amphiphiles to aggregate to very long fibe

  16. In Search of the Chiral Regime

    CERN Document Server

    Beane, S R

    2004-01-01

    A critical appraisal is given of a recent analysis of the quark-mass and finite-size dependence of unquenched lattice QCD data for the nucleon mass. We use this forum to estimate the boundary of the chiral regime for nucleon properties.

  17. Quenched QCD near the chiral limit

    CERN Document Server

    Göckeler, M; Petters, D; Pleiter, D; Rakow, P E L; Schierholz, G

    2000-01-01

    A numerical study of quenched QCD for light quarks is presented using O(a)improved fermions. Particular attention is paid to the possible existence anddetermination of quenched chiral logarithms. A `safe' region to use for chiralextrapolations appears to be at and above the strange quark mass.

  18. Chiral effective field theory and nuclear forces

    CERN Document Server

    Machleidt, R

    2011-01-01

    We review how nuclear forces emerge from low-energy QCD via chiral effective field theory. The presentation is accessible to the non-specialist. At the same time, we also provide considerable detailed information (mostly in appendices) for the benefit of researchers who wish to start working in this field.

  19. Chiral separation and twin-beam photonics

    Science.gov (United States)

    Bradshaw, David S.; Andrews, David L.

    2016-03-01

    It is well-known that, in a homogeneous fluid medium, most optical means that afford discrimination between molecules of opposite handedness are intrinsically weak effects. The reason is simple: the wide variety of origins for differential response commonly feature real or virtual electronic transitions that break a parity condition. Despite being electric dipole allowed, they manifest the chirality of the material in which they occur by breaking a selection rule that would otherwise preclude the simultaneous involvement of magnetic dipole or electric quadrupole forms of coupling. Although the latter are typically weaker than electric dipole effects by several orders of magnitude, it is the involvement of these weak forms of interaction that are responsible for chiral sensitivity. There have been a number of attempts to cleverly exploit novel optical configurations to enhance the relative magnitude - and hence potentially the efficiency - of chiral discrimination. The prospect of success in any such venture is enticing, because of the huge impact that such an advance might be expected to have in the health, food and medical sectors. Some of these proposals have utilized mirror reflection, and others surface plasmon coupling, or optical binding methods. Several recent works in the literature have drawn attention to a further possibility: the deployment of optical beam interference as a means to achieve chiral separations of sizeable extent. In this paper the underlying theory is fully developed to identify the true scope and limitations of such an approach.

  20. The development of chiral nematic mesoporous materials.

    Science.gov (United States)

    Kelly, Joel A; Giese, Michael; Shopsowitz, Kevin E; Hamad, Wadood Y; MacLachlan, Mark J

    2014-04-15

    Cellulose nanocrystals (CNCs) are obtained from the sulfuric acid-catalyzed hydrolysis of bulk cellulose. The nanocrystals have diameters of ~5-15 nm and lengths of ~100-300 nm (depending on the cellulose source and hydrolysis conditions). This lightweight material has mostly been investigated to reinforce composites and polymers because it has remarkable strength that rivals carbon nanotubes. But CNCs have an additional, less explored property: they organize into a chiral nematic (historically referred to as cholesteric) liquid crystal in water. When dried into a thin solid film, the CNCs retain the helicoidal chiral nematic order and assemble into a layered structure where the CNCs have aligned orientation within each layer, and their orientation rotates through the stack with a characteristic pitch (repeating distance). The cholesteric ordering can act as a 1-D photonic structure, selectively reflecting circularly polarized light that has a wavelength nearly matching the pitch. During CNC self-assembly, it is possible to add sol-gel precursors, such as Si(OMe)4, that undergo hydrolysis and condensation as the solvent evaporates, leading to a chiral nematic silica/CNC composite material. Calcination of the material in air destroys the cellulose template, leaving a high surface area mesoporous silica film that has pore diameters of ~3-10 nm. Importantly, the silica is brilliantly iridescent because the pores in its interior replicate the chiral nematic structure. These films may be useful as optical filters, reflectors, and membranes. In this Account, we describe our recent research into mesoporous films with chiral nematic order. Taking advantage of the chiral nematic order and nanoscale of the CNC templates, new functional materials can be prepared. For example, heating the silica/CNC composites under an inert atmosphere followed by removal of the silica leaves highly ordered, mesoporous carbon films that can be used as supercapacitor electrodes. The composition

  1. Low-energy analysis of the nucleon electromagnetic form factors 12.39.Fe; 13.40.Gp; 14.20.Dh; Nucleon electromagnetic form factors; Chiral perturbation theory

    CERN Document Server

    Kubis, B

    2001-01-01

    We analyze the electromagnetic form factors of the nucleon to fourth order in relativistic baryon chiral perturbation theory. We employ the recently proposed infrared regularization scheme and show that the convergence of the chiral expansion is improved as compared to the heavy-fermion approach. We also discuss the inclusion of vector mesons and obtain an accurate description of all four-nucleon form factors for momentum transfer squared up to Q sup 2 approx =0.4 GeV sup 2.

  2. Chiral Sensitivity in Electron-Molecule Interactions

    Science.gov (United States)

    Dreiling, Joan

    2015-09-01

    All molecular forms of life possess a chiral asymmetry, with amino acids and sugars found respectively in L- and D-enantiomers only. The primordial origin of this enantiomeric excess is unknown. One possible explanation is given by the Vester- Ulbricht hypothesis, which suggests that left-handed electrons present in beta-radiation, produced by parity-violating weak decays, interacted with biological precursors and preferentially destroyed one of the two enantiomers. Experimental tests of this idea have thus far yielded inconclusive results. We show direct evidence for chirally-dependent bond breaking through a dissociative electron attachment (DEA) reaction when spin-polarized electrons are incident on gas-phase chiral molecules. This provides unambiguous evidence for a well-defined, chirally-sensitive destructive molecular process and, as such, circumstantial evidence for the Vester-Ulbricht hypothesis. I will also present the results of our systematic study of the DEA asymmetry for different chiral halocamphor molecules. Three halocamphor molecules were investigated: 3-bromocamphor (C10H15BrO), 3-iodocamphor(C10H15IO), and 10-iodocamphor. The DEA asymmetries collected for bromocamphor and iodocamphor are qualitatively different, suggesting that the atomic number of the heaviest atom in the molecule plays a crucial role in the asymmetric interactions. The DEA asymmetry data for 3- and 10-iodocamphor have the same qualitative behavior, but the 10-iodocamphor asymmetry is about twice as large at the lowest energies investigated, so the location of the heavy atom in the camphor molecule also affects the asymmetries. This work was performed at the University of Nebraska-Lincoln. This project is funded by NSF Grant PHY-1206067.

  3. Transition State Models for Understanding the Origin of Chiral Induction in Asymmetric Catalysis.

    Science.gov (United States)

    Sunoj, Raghavan B

    2016-05-17

    transition states of five reaction types, three of which provide access to chiral quaternary carbon atoms. While each reaction has its own utility and interest, the focus of our research has been on the mechanism and the origin of the enantio- and diastereoselectivity. In all of the examples, such as asymmetric diamination, sulfoxidation, allylation, and Wacker-type ring expansion, the role played by non-covalent interactions in the stereocontrolling transition states has been identified as crucial. The transfer of the chiral information from the chiral catalyst to the product is identified as taking place through a series of non-covalent interactions between the catalyst and a given position/orientation of the substrate in the chiral environment offered by the axially chiral catalyst. The molecular insights enunciated herein allude to abundant opportunities for rational modifications of the present generation of catalysts and the choice of substrates in these as well as related families of reactions. It is our intent to propose that the domain of asymmetric catalysis could enjoy additional benefits by having knowledge of the vital stereoelectronic interactions in the stereocontrolling transition states.

  4. Optical properties and circular dichroism of chiral metal nanoparticles

    Science.gov (United States)

    Fan, Zhiyuan; Govorov, Alexander; OU Team

    2013-03-01

    In nature, biological systems are built up by homochiral building blocks, such as a sugar and protein. Circular dichroism (CD) is an effective tool of resolving molecular conformations. It utilizes circularly polarized light to detect differential absorption of chiral materials. In medicine, it will help us to develop new drugs and therapies, if we understand the connection between the physical or chemical properties of drug molecules and their conformations. With the rapid development of nanotechnologies, chiral nanomaterials attract lots of attention nowadays. CD signals of chiral molecules can be enhanced or shifted to the visible band in the presence of plasmonic nanocrystals. Here we present a plasmonic CD mechanism from a single chiral metal nanocrystal. The mechanism is essentially different from the dipolar plasmon-plasmon interaction in a chiral NP assembly, which mimics the CD mechanism of chiral molecules. Chiral metal nanocrystals are expected to have promising applications in biosensing. Recently a few experimental papers reported successful realizations of chiral nanocrystals in a macroscopic ensemble in solution. Particularly the paper described silver nanoparticles grown on chiral template molecules and demonstrating characteristic CD signals at a plasmonic wavelength. The plasmonic CD signals in Ref. can come from a dipolar plasmon-molecule interaction or from a chiral shape of nanocrystals. This work was supported by the NSF (project: CBET- 0933782) and by the Volkswagen Foundation.

  5. Chiral corrections to the Adler-Weisberger sum rule

    Science.gov (United States)

    Beane, Silas R.; Klco, Natalie

    2016-12-01

    The Adler-Weisberger sum rule for the nucleon axial-vector charge, gA , offers a unique signature of chiral symmetry and its breaking in QCD. Its derivation relies on both algebraic aspects of chiral symmetry, which guarantee the convergence of the sum rule, and dynamical aspects of chiral symmetry breaking—as exploited using chiral perturbation theory—which allow the rigorous inclusion of explicit chiral symmetry breaking effects due to light-quark masses. The original derivations obtained the sum rule in the chiral limit and, without the benefit of chiral perturbation theory, made various attempts at extrapolating to nonvanishing pion masses. In this paper, the leading, universal, chiral corrections to the chiral-limit sum rule are obtained. Using PDG data, a recent parametrization of the pion-nucleon total cross sections in the resonance region given by the SAID group, as well as recent Roy-Steiner equation determinations of subthreshold amplitudes, threshold parameters, and correlated low-energy constants, the Adler-Weisberger sum rule is confronted with experimental data. With uncertainty estimates associated with the cross-section parametrization, the Goldberger-Treimann discrepancy, and the truncation of the sum rule at O (Mπ4) in the chiral expansion, this work finds gA=1.248 ±0.010 ±0.007 ±0.013 .

  6. Baryons in the chiral regime

    Energy Technology Data Exchange (ETDEWEB)

    Knippschild, Bastian

    2012-03-05

    Quantum Chromodynamics (QCD) is the theory of strong interactions, one of the four fundamental forces in our Universe. It describes the interaction of gluons and quarks which build up hadrons like protons and neutrons. Most of the visible matter in our universe is made of protons and neutrons. Hence, we are interested in their fundamental properties like their masses, their distribution of charge and their shape. The only known theoretical, non-perturbative and ab initio method to investigate hadron properties at low energies is lattice Quantum Chromodynamics (lattice QCD). However, up-to-date simulations (especially for baryonic quantities) do not achieve the accuracy of experiments. In fact, current simulations do not even reproduce the experimental values for the form factors. The question arises wether these deviations can be explained by systematic effects in lattice QCD simulations. This thesis is about the computation of nucleon form factors and other hadronic quantities from lattice QCD. So called Wilson fermions are used and the u- and d-quarks are treated fully dynamically. The simulations were performed using gauge ensembles with a range of lattice spacings, volumes and pion masses. First of all, the lattice spacing was set to be able to make contact between the lattice results and their experimental complement and to be able to perform a continuum extrapolation. The light quark mass has been computed and found to be m{sub ud}{sup MS}(2 GeV)=3.03(17)(38) MeV. This value is in good agreement with values from experiments and other lattice determinations. Electro-magnetic and axial form factors of the nucleon have been calculated. From these form factors the nucleon radii and the coupling constants were computed. The different ensembles enabled us to investigate systematically the dependence of these quantities on the volume, the lattice spacing and the pion mass. Finally we perform a continuum extrapolation and chiral extrapolations to the physical point

  7. Analysis of Chiral Carboxylic Acids in Meteorites

    Science.gov (United States)

    Burton, A. S.; Elsila, J. E.; Hein, J. E.; Aponte, J. C.; Parker, E. T.; Glavin, D. P.; Dworkin, J. P.

    2015-01-01

    Homochirality of amino acids in proteins and sugars in DNA and RNA is a critical feature of life on Earth. In the absence of a chiral driving force, however, reactions leading to the synthesis of amino acids and sugars result in racemic mixtures. It is currently unknown whether homochirality was necessary for the origins of life or if it was a product of early life. The observation of enantiomeric excesses of certain amino acids of extraterrestrial origins in meteorites provides evidence to support the hypothesis that there was a mechanism for the preferential synthesis or destruction of a particular amino acid enantiomer [e.g., 1-3]. The cause of the observed chiral excesses is un-clear, although at least in the case of the amino acid isovaline, the degree of aqueous alteration that occurred on the meteorite parent body is correlated to the isovaline L-enantiomeric excess [3, 4]. This suggests that chiral symmetry is broken and/or amplified within the meteorite parent bodies. Besides amino acids, there have been only a few reports of other meteoritic compounds found in enantiomeric excess: sugars and sugar acids [5, 6] and the hydroxy acid lactic acid [7]. Determining whether or not additional types of molecules in meteorites are also present in enantiomeric excesses of extraterrestrial information will provide insights into mechanisms for breaking chiral symmetry. Though the previous measurements (e.g., enantiomeric composition of lactic acid [7], and chiral carboxylic acids [8]) were made by gas chromatography-mass spectrometry, the potential for increased sensitivity of liquid chromatography-mass spectrometry (LC-MS) analyses is important because for many meteorite samples, only small sample masses are available for study. Furthermore, at least in the case of amino acids, many of the largest amino acid enantiomeric excesses were observed in samples that contained lower abundances (tens of ppb) of a given amino acid enantiomer. In the present work, we describe

  8. Model of complex chiral drug metabolic systems and numerical simulation of the remaining chirality toward analysis of dynamical pharmacological activity.

    Science.gov (United States)

    Ogino, Yoshiyuki; Asahi, Toru

    2015-05-21

    In this study, systems of complicated pathways involved in chiral drug metabolism were investigated. The development of chiral drugs resulted in significant improvement in the remedies available for the treatment of various severe sicknesses. Enantiopure drugs undergo various biological transformations that involve chiral inversion and thus result in the generation of multiple enantiomeric metabolites. Identification of the specific active substances determining a given drug׳s efficacy among such a mixture of different metabolites remains a challenge. To comprehend this complexity, we constructed a mathematical model representing the complicated metabolic pathways simultaneously involving chiral inversion. Moreover, this model is applied to the metabolism of thalidomide, which has recently been revived as a potentially effective prescription drug for a number of intractable diseases. The numerical simulation results indicate that retained chirality in the metabolites reflects the original chirality of the unmetabolized drug, and a higher level of enantiomeric purity is preserved during spontaneous degradation. In addition, chirality remaining after equilibration is directly related to the rate constant not only for chiral inversion but also for generation and degradation. Furthermore, the retention of chirality is quantitatively predictable using this combination of kinetic parameters. Our simulation results well explain the behavior of thalidomide in the practical biological experimental data. Therefore, this model promises a comprehensive understanding of dynamic metabolic systems involving chiral drugs that express multiple enantiospecific drug efficacies.

  9. Molecular-Level Design of Heterogeneous Chiral Catalysis

    Energy Technology Data Exchange (ETDEWEB)

    Francisco Zaera

    2012-03-21

    The following is a proposal to continue our multi-institutional research on heterogeneous chiral catalysis. Our team combines the use of surface-sensitive analytical techniques for the characterization of model systems with quantum and statistical mechanical calculations to interpret experimental data and guide the design of future research. Our investigation focuses on the interrelation among the three main mechanisms by which enantioselectivity can be bestowed to heterogeneous catalysts, namely: (1) by templating chirality via the adsorption of chiral supramolecular assemblies, (2) by using chiral modifiers capable of forming chiral complexes with the reactant and force enantioselective surface reactions, and (3) by forming naturally chiral surfaces using imprinting chiral agents. Individually, the members of our team are leaders in these various aspects of chiral catalysis, but the present program provides the vehicle to generate and exploit the synergies necessary to address the problem in a comprehensive manner. Our initial work has advanced the methodology needed for these studies, including an enantioselective titration procedure to identify surface chiral sites, infrared spectroscopy in situ at the interface between gases or liquids and solids to mimic realistic catalytic conditions, and DFT and Monte Carlo algorithms to simulate and understand chirality on surfaces. The next step, to be funded by the monies requested in this proposal, is to apply those methods to specific problems in chiral catalysis, including the identification of the requirements for the formation of supramolecular surface structures with enantioselective behavior, the search for better molecules to probe the chiral nature of the modified surfaces, the exploration of the transition from supramolecular to one-to-one chiral modification, the correlation of the adsorption characteristics of one-to-one chiral modifiers with their physical properties, in particular with their configuration

  10. Spin Chirality of Cu3 and V3 Nanomagnets. 1. Rotation Behavior of Vector Chirality, Scalar Chirality, and Magnetization in the Rotating Magnetic Field, Magnetochiral Correlations.

    Science.gov (United States)

    Belinsky, Moisey I

    2016-05-02

    The rotation behavior of the vector chirality κ, scalar chirality χ, and magnetization M in the rotating magnetic field H1 is considered for the V3 and Cu3 nanomagnets, in which the Dzialoshinsky-Moriya coupling is active. The polar rotation of the field H1 of the given strength H1 results in the energy spectrum characterized by different vector and scalar chiralities in the ground and excited states. The magnetochiral correlations between the vector and scalar chiralities, energy, and magnetization in the rotating field were considered. Under the uniform polar rotation of the field H1, the ground-state chirality vector κI performs sawtooth oscillations and the magnetization vector MI performs the sawtooth oscillating rotation that is accompanied by the correlated transformation of the scalar chirality χI. This demonstrates the magnetochiral effect of the joint rotation behavior and simultaneous frustrations of the spin chiralities and magnetization in the rotating field, which are governed by the correlation between the chiralities and magnetization.

  11. Chiral assembly of weakly curled hard rods: Effect of steric chirality and polarity

    Energy Technology Data Exchange (ETDEWEB)

    Wensink, H. H., E-mail: wensink@lps.u-psud.fr; Morales-Anda, L. [Laboratoire de Physique des Solides–UMR 8502, Université Paris-Sud & CNRS, 91405 Orsay (France)

    2015-10-14

    We theoretically investigate the pitch of lyotropic cholesteric phases composed of slender rods with steric chirality transmitted via a weak helical deformation of the backbone. In this limit, the model is amenable to analytical treatment within Onsager theory and a closed expression for the pitch versus concentration and helical shape can be derived. Within the same framework, we also briefly review the possibility of alternative types of chiral order, such as twist-bend or screw-like nematic phases, finding that cholesteric order dominates for weakly helical distortions. While long-ranged or “soft” chiral forces usually lead to a pitch decreasing linearly with concentration, steric chirality leads to a much steeper decrease of quadratic nature. This reveals a subtle link between the range of chiral intermolecular interaction and the pitch sensitivity with concentration. A much richer dependence on the thermodynamic state is revealed for polar helices where parallel and anti-parallel pair alignments along the local director are no longer equivalent. It is found that weak temperature variations may lead to dramatic changes in the pitch, despite the lyotropic nature of the assembly.

  12. Emergence of collective dynamical chirality for achiral active particles.

    Science.gov (United States)

    Jiang, Huijun; Ding, Huai; Pu, Mingfeng; Hou, Zhonghuai

    2017-01-25

    Emergence of collective dynamical chirality (CDC) at mesoscopic scales plays a key role in many formation processes of chiral structures in nature, which may also provide possible routines for people to fabricate complex chiral architectures. So far, most of the reported CDCs have been found in systems of active objects with individual structure chirality or/and dynamical chirality, and whether CDC can arise from simple and achiral units is still an attractive mystery. Here, we report a spontaneous formation of CDC in a system of both dynamically and structurally achiral particles motivated by active motion of cells adhered onto a substrate. Active motion, confinement and hydrodynamic interaction are found to be the three key factors. Detailed analysis shows that the system can support abundant collective dynamical behaviors, including rotating droplets, rotating bubbles, CDC oscillations, arrays of collective rotations, and interesting transitions such as chirality transition, structure transition and state reentrance.

  13. A molecular propeller effect for chiral separation and analysis

    Science.gov (United States)

    Clemens, Jonathon B.; Kibar, Osman; Chachisvilis, Mirianas

    2015-07-01

    Enantiomers share nearly identical physical properties but have different chiral geometries, making their identification and separation difficult. Here we show that when exposed to a rotating electric field, the left- and right-handed chiral molecules rotate with the field and act as microscopic propellers; moreover, owing to their opposite handedness, they propel along the axis of field rotation in opposite directions. We introduce a new molecular parameter called hydrodynamic chirality to characterize the coupling of rotational motion of a chiral molecule into its translational motion and quantify the direction and velocity of such motion. We demonstrate >80% enrichment level of counterpart enantiomers in solution without using chiral selectors or circularly polarized light. We expect our results to have an impact on multiple applications in drug discovery, analytical and chiral chemistry, including determination of absolute configuration, as well as in influencing the understanding of artificial and natural molecular systems where rotational motion of the molecules is involved.

  14. Microstructure Effects for Casimir Forces in Chiral Metamaterials

    CERN Document Server

    McCauley, Alexander P; Reid, M T Homer; Rodriguez, Alejandro W; Zhou, Jiangfeng; Rosa, F S S; Joannopoulos, John D; Dalvit, D A R; Soukoulis, Costas M; Johnson, Steven G

    2010-01-01

    We examine a recent prediction for the chirality-dependence of the Casimir force in chiral metamaterials by numerical computation of the forces between the exact microstructures, rather than homogeneous approximations. We compute the exact force for a chiral bent-cross pattern, as well as forces for an idealized "omega"-particle medium in the dilute approximation and identify the effects of structural inhomogeneity (i.e. proximity forces and anisotropy). We find that these microstructure effects dominate the force for separations where chirality was predicted to have a strong influence. To get observations of chirality free from microstructure effects, one must go to large separations where the effect of chirality is at most $\\sim10^{-4}$ of the total force.

  15. Designing large scale chiral metamaterials by nanosphere shadowing lithography

    Science.gov (United States)

    He, Yizhuo; Zhao, Yiping

    2016-09-01

    A scalable nanofabrication technique for chiral metamaterials is presented, which combines the dynamic shadowing growth and self-assembled nanosphere monolayers, and is also known as nanosphere shadowing lithography. We have developed two strategies based on nanosphere shadowing lithography to prepare chiral nanostructures. The first strategy is to create a quasi-three-dimensional single-layer fan-shaped chiral nanostructure on nanospheres with one plasmonic material. The second strategy is to create three-dimensional multi-layers helical nanostructures with one plasmonic material and one dielectric material. Both strategies can produce large-area chiral nanostructures with strong chiral optical response, which makes nanosphere shadowing lithography suitable for producing chiral metamaterial based devices such as an ultrathin narrow-band circular polarizer.

  16. Chiral medium produced by parallel electric and magnetic fields

    CERN Document Server

    Ruggieri, Marco; Chernodub, Maxim

    2016-01-01

    We compute (pseudo)critical temperature, $T_c$, of chiral symmetry restoration for quark matter in the background of parallel electric and magnetic fields. This field configuration leads to the production of a chiral medium on a time scale $\\tau$, characterized by a nonvanishing value of the chiral density that equilibrates due to microscopic processes in the thermal bath. We estimate the relaxation time $\\tau$ to be about $\\approx 0.1-1$ fm/c around the chiral crossover; then we compute the effect of the fields and of the chiral medium on~$T_c$. We find $T_c$ to be lowered by the external fields in the chiral medium.

  17. Chiral spiral induced by a strong magnetic field

    CERN Document Server

    Abuki, H

    2016-01-01

    We study the modification of the chiral phase structure of QCD due to an external magnetic field. We first demonstrate how the effect of magnetic field can systematically be incorporated into a generalized Ginzburg-Landau framework. We then analyze the phase structure in the vicinity of the chiral critical point. In the chiral limit, the effect is found to be so drastic that it totally washes the tricritical point out of the phase diagram, bringing the continent for the chiral spiral. This is the case no matter how small is the intensity of the magnetic field. On the other hand, the current quark mass protects the chiral critical point from a weak magnetic field. However the critical point will eventually be covered by the chiral spiral phase as the magnetic field grows.

  18. Chiral metamaterial design using optimized pixelated inclusions with genetic algorithm

    Science.gov (United States)

    Akturk, Cemal; Karaaslan, Muharrem; Ozdemir, Ersin; Ozkaner, Vedat; Dincer, Furkan; Bakir, Mehmet; Ozer, Zafer

    2015-03-01

    Chiral metamaterials have been a research area for many researchers due to their polarization rotation properties on electromagnetic waves. However, most of the proposed chiral metamaterials are designed depending on experience or time-consuming inefficient simulations. A method is investigated for designing a chiral metamaterial with a strong and natural chirality admittance by optimizing a grid of metallic pixels through both sides of a dielectric sheet placed perpendicular to the incident wave by using a genetic algorithm (GA) technique based on finite element method solver. The effective medium parameters are obtained by using constitutive equations and S parameters. The proposed methodology is very efficient for designing a chiral metamaterial with the desired effective medium parameters. By using GA-based topology, it is proven that a chiral metamaterial can be designed and manufactured more easily and with a low cost.

  19. Manipulating the Lorentz force via the chirality of nanoparticles

    Science.gov (United States)

    Wang, Maoyan; Li, Hailong; Dong, Yuliang; Zhang, Xiaochuan; Du, Ming; Wang, Rui; Xu, Tong; Wu, Jian

    2016-12-01

    We demonstrate that a single plane wave pulls a chiral nanoparticle toward the light source. The nanoparticle exhibits optical gain in a particular wavelength region. The equivalence of the generalized and alternative expressions of the Lorentz force density relating to bound charges for chiral media is numerically validated. By considering the two-dimensional electromagnetic problem of incident plane waves normally impinged on active chiral cylinders, it is shown that the gradient force is mainly contributed by the bound electric and magnetic current densities of the cross-polarized waves. We also investigate how the medium parameters and impedance mismatch can be used to manipulate the pulling or pushing Lorentz forces between two chiral cylinders. This finding may provide a recipe to understand the light interaction with multiple chiral nanoparticles of arbitrary shapes (in general) with the aid of the numerical approach. It could be a promising avenue in controlling the optical micromanipulation for chiral nanoparticles with mirroring asymmetry.

  20. Study of surface plasmon chirality induced by Archimedes' spiral grooves.

    Science.gov (United States)

    Ohno, Tomoki; Miyanishi, Shintaro

    2006-06-26

    A chirality of surface plasmons excited on a silver film with Archimedes' spiral grooves during incidence of a circularly polarized light is analytically and numerically studied by using the finite-difference time-domain (FDTD) modeling method. We found that the surface of a plasmon has selective chirality, which is given by the sum of the chiralities of the incident light and the spiral structure. The surface plasmons with the chirality lead to zero-order, first-order, and high-order evanescent Bessel beams with electric charge distributions on the film. This selectivity could be widely applied for chiral detection of the incident light and chiral excitation of several optical modes in nanophotonics.

  1. Detecting chirality in molecules by linearly polarized laser fields

    CERN Document Server

    Yachmenev, Andrey

    2016-01-01

    A new scheme for enantiomer differentiation of chiral molecules using a pair of linearly polarized intense ultrashort laser pulses with skewed mutual polarization is presented. The technique relies on the fact that the off-diagonal anisotropic contributions to the electric polarizability tensor for two enantiomers have different signs. Exploiting this property, we are able to excite a coherent unidirectional rotation of two enantiomers with a {\\pi} phase difference in the molecular electric dipole moment. The approach is robust and suitable for relatively high temperatures of molecular samples, making it applicable for selective chiral analysis of mixtures, and to chiral molecules with low barriers between enantiomers. As an illustration, we present nanosecond laser-driven dynamics of a tetratomic non-rigid chiral molecule with short-lived chirality. The ultrafast time scale of the proposed technique is well suited to study parity violation in molecular systems in short-lived chiral states.

  2. Development of chiral sulfoxide ligands for asymmetric catalysis.

    Science.gov (United States)

    Trost, Barry M; Rao, Meera

    2015-04-20

    Nitrogen-, phosphorus-, and oxygen-based ligands with chiral backbones have been the historic workhorses of asymmetric transition-metal-catalyzed reactions. On the contrary, sulfoxides containing chirality at the sulfur atom have mainly been used as chiral auxiliaries for diastereoselective reactions. Despite several distinct advantages over traditional ligand scaffolds, such as the proximity of the chiral information to the metal center and the ability to switch between S and O coordination, these compounds have only recently emerged as a versatile class of chiral ligands. In this Review, we detail the history of the development of chiral sulfoxide ligands for asymmetric catalysis. We also provide brief descriptions of metal-sulfoxide bonding and strategies for the synthesis of enantiopure sulfoxides. Finally, insights into the future development of this underutilized ligand class are discussed.

  3. Bootstrapping ${\\mathcal N}=2$ chiral correlators

    CERN Document Server

    Lemos, Madalena

    2016-01-01

    We apply the numerical bootstrap program to chiral operators in four-dimensional ${\\mathcal N}=2$ SCFTs. In the first part of this work we study four-point functions in which all fields have the same conformal dimension. We give special emphasis to bootstrapping a specific theory: the simplest Argyres-Douglas fixed point with no flavor symmetry. In the second part we generalize our setup and consider correlators of fields with unequal dimension. This is an example of a mixed correlator and allows us to probe new regions in the parameter space of ${\\mathcal N}=2$ SCFTs. In particular, our results put constraints on relations in the Coulomb branch chiral ring and on the curvature of the Zamolodchikov metric.

  4. A Nonperturbative Regulator for Chiral Gauge Theories

    CERN Document Server

    Grabowska, Dorota M

    2015-01-01

    We propose a nonperturbative gauge invariant regulator for $d$-dimensional chiral gauge theories on the lattice. The method involves simulating domain wall fermions in $d+1$ dimensions with quantum gauge fields that reside on one $d$-dimensional surface and are extended into the bulk via gradient flow. The result is a theory of gauged fermions plus mirror fermions, where the mirror fermions couple to the gauge fields via a form factor that becomes exponentially soft with the separation between domain walls. The resultant theory has a local $d$-dimensional interpretation if and only if the chiral fermion representation is anomaly free. A physical realization of this construction leads to mirror fermions in the Standard Model with soft form factors for gauge fields and gravity. These mirror particles could evade detection except by sensitive probes at extremely low energy, and yet still affect vacuum topology, and could gravitate differently than conventional matter.

  5. Optical Tractor Beam with Chiral Light

    CERN Document Server

    Fernandes, David E

    2015-01-01

    We suggest a novel mechanism to induce the motion of a chiral material body towards an optical source. Our solution is based on the interference between a chiral light beam and its reflection on an opaque mirror. Surprisingly, it is theoretically shown that the electromagnetic response of the material may be tailored in such a way that independent of the specific body location with the respect to the mirror, it is always pushed upstream against the photon flow associated with the incoming wave. Moreover, it is proven that by controlling the handedness of the incoming light it may be possible to harness the sign of the optical force, switching from a pulling force to a pushing force.

  6. Random Matrices and Chiral Symmetry in QCD

    CERN Document Server

    Janik, R A; Papp, G; Zahed, I; Janik, Romuald A.; Nowak, Maciej A.; Papp, Gabor; Zahed, Ismail

    1998-01-01

    In this talk we review some recent results from random matrix models as applied to some non-perturbative issues in QCD. All of the issues we will discuss touched upon the important phenomenon related to the spontaneous breaking of chiral symmetry. The afore mentioned insights are: 1. Spontaneous breakdown of chiral symmetry and disorder. 2. Universal microscopic properties of the eigenvalues of the Dirac operator in the vacuum. 3. Universal microscopic properties of the eigenvalues of the Dirac operator in matter. 4. Structural changes of the Dirac spectrum - finite temperature. 5. Structural changes of the Dirac spectrum - finite baryonic density - ``phony vacua'' 6. Structural changes of the Dirac spectrum - finite baryonic density - ``true vacua'' . 7. Phase diagram. 8. Critical parameters. 9. Critical exponents. 10. $U(1)_A$ problem. 11. Screening of the pseudoscalar susceptibility. 12. Strong CP violation (finite $\\theta$).

  7. Active control of chirality in nonlinear metamaterials

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Yu; Chai, Zhen; Yang, Hong [State Key Laboratory for Mesoscopic Physics and Department of Physics, Peking University, Beijing 100871 (China); Hu, Xiaoyong, E-mail: xiaoyonghu@pku.edu.cn; Gong, Qihuang [State Key Laboratory for Mesoscopic Physics and Department of Physics, Peking University, Beijing 100871 (China); Collaborative Innovation Center of Quantum Matter, Beijing 100871 (China)

    2015-03-02

    An all-optical tunabe chirality is realized in a photonic metamaterial, the metamolecule of which consists of a nonlinear nano-Au:polycrystalline indium-tin oxide layer sandwiched between two L-shaped gold nano-antennas twisted 90° with each other. The maximum circular dichroism reached 30%. Under excitation of a 40 kW/cm{sup 2} weak pump light, the peak in the circular dichroism shifts 45 nm in the short-wavelength direction. An ultrafast response time of 35 ps is maintained. This work not only opens up the possibility for the realization of ultralow-power and ultrafast all-optical tunable chirality but also offers a way to construct ultrahigh-speed on-chip biochemical sensors.

  8. A primer for Chiral Perturbative Theory

    Energy Technology Data Exchange (ETDEWEB)

    Scherer, Stefan [Mainz Univ. (Germany). Inst. fuer Kernphysik; Schindler, Matthias R. [South Carolina Univ., Columbia, SC (United States). Dept. of Physics; George Washington Univ., Washington, DC (United States). Dept. of Physics

    2012-07-01

    Chiral Perturbation Theory, as effective field theory, is a commonly accepted and well established working tool, approximating quantum chromodynamics at energies well below typical hadron masses. This volume, based on a number of lectures and supplemented with additional material, provides a pedagogical introduction for graduate students and newcomers entering the field from related areas of nuclear and particle physics. Starting with the the Lagrangian of the strong interactions and general symmetry principles, the basic concepts of Chiral Perturbation Theory in the mesonic and baryonic sectors are developed. The application of these concepts is then illustrated with a number of examples. A large number of exercises (81, with complete solutions) are included to familiarize the reader with helpful calculational techniques. (orig.)

  9. Oscillating Chiral Tensor Spectrum from Axionic Inflation

    CERN Document Server

    Obata, Ippei

    2016-01-01

    We study the axionic inflation with a modulated potential and examine if the primordial tensor power spectrum exhibits oscillatory feature, which is testable with future space-based gravitational wave experiments such as DECIGO and BBO. In the case of the single-field axion monodromy inflation, it turns out that it is difficult to detect the oscillation in the spectrum due to suppression of the sub-Planckian decay constant of axion. On the other hand, in the case of aligned chromo-natural inflation where the axion is coupled to a SU(2) gauge field, it turns out that the sizable oscillation in the tensor spectrum can occur due to the enhancement of chiral gravitational waves sourced by the gauge field. We expect that this feature will be a new probe to axion phenomenologies in early universe through the chiral gravitational waves.

  10. Chiral transition and deconfinement in QCD

    CERN Document Server

    D'Elia, M; Pica, C

    2006-01-01

    The study of QCD with two light dynamical fermions is of fundamental importance to understand the mechanism of color confinement. We present results of a numerical investigation on the order of the chiral phase transition with $N_f = 2$ by use of a novel strategy in finite size scaling analysis. We compare the critical behaviour of the specific heat, of the chiral susceptibility and of the equation of state with the possible critical behaviours. A second order transition in the O(4) and O(2) universality classes are excluded by our data and substantial evidence emerges for a first order transition. Like in most of previous works we have used the standard staggered action with $L_t = 4$: possible scaling violations and the need for further studies are discussed.

  11. Chiral fermions in asymptotically safe quantum gravity

    Energy Technology Data Exchange (ETDEWEB)

    Meibohm, J. [Gothenburg University, Department of Physics, Goeteborg (Sweden); Universitaet Heidelberg, Institut fuer Theoretische Physik, Heidelberg (Germany); Pawlowski, J.M. [Universitaet Heidelberg, Institut fuer Theoretische Physik, Heidelberg (Germany); GSI Helmholtzzentrum fuer Schwerionenforschung mbH, ExtreMe Matter Institute EMMI, Darmstadt (Germany)

    2016-05-15

    We study the consistency of dynamical fermionic matter with the asymptotic safety scenario of quantum gravity using the functional renormalisation group. Since this scenario suggests strongly coupled quantum gravity in the UV, one expects gravity-induced fermion self-interactions at energies of the Planck scale. These could lead to chiral symmetry breaking at very high energies and thus to large fermion masses in the IR. The present analysis which is based on the previous works (Christiansen et al., Phys Rev D 92:121501, 2015; Meibohm et al., Phys Rev D 93:084035, 2016), concludes that gravity-induced chiral symmetry breaking at the Planck scale is avoided for a general class of NJL-type models. We find strong evidence that this feature is independent of the number of fermion fields. This finding suggests that the phase diagram for these models is topologically stable under the influence of gravitational interactions. (orig.)

  12. Magnetic rotation and chiral symmetry breaking

    Indian Academy of Sciences (India)

    Ashok Kumar Jain; Amita

    2001-08-01

    The deformed mean field of nuclei exhibits various geometrical and dynamical symmetries which manifest themselves as various types of rotational and decay patterns. Most of the symmetry operations considered so far have been defined for a situation wherein the angular momentum coincides with one of the principal axes and the principal axis cranking may be invoked. New possibilities arise with the observation of rotational features in weakly deformed nuclei and now interpreted as magnetic rotational bands. More than 120 MR bands have now been identified by filtering the existing data. We present a brief overview of these bands. The total angular momentum vector in such bands is tilted away from the principal axes. Such a situation gives rise to several new possibilities including breaking of chiral symmetry as discussed recently by Frauendorf. We present the outcome of such symmetries and their possible experimental verification. Some possible examples of chiral bands are presented.

  13. Chiral discrimination in biomimetic systems: Phenylalanine

    Indian Academy of Sciences (India)

    K Thirumoorthy; K Soni; T Arun; N Nandi

    2007-09-01

    Chiral discrimination and recognition is important in peptide biosynthesis, amino acid synthesis and drug designing. Detailed structural information is available about the peptide synthesis in ribosome. However, no detailed study is available about the discrimination in peptide synthesis. We study the conformational energy variation of neutral methoxy phenyl alanine molecule as a function of its different dihedral angle to locate the minimum energy conformation using quantum chemical theory. We compared the intermolecular energy surfaces of phenyl alanine molecule in its neutral and zwitterionic state using quantum chemical theory as a function of distance and mutual orientation. The energy surfaces are studied with rigid geometry by varying the distance and orientation. The potential energy surfaces of - and - pairs are found to be dissimilar and reflect the underlying chirality of the homochiral pair and racemic nature of the heterochiral pair. The intermolecular energy surface of homochiral pair is more favourable than the corresponding energy surface of heterochiral pair.

  14. Helical chirality induction of expanded porphyrin analogues

    Indian Academy of Sciences (India)

    Jun-Ichiro Setsune

    2012-11-01

    Expanded porphyrin analogues with unique figure-eight conformation were prepared by way of useful pyrrole intermediates such as bis(azafulvene)s and 2-borylpyrrole. Supramolecular chirogenesis of cyclooctapyrrole O1 with 32-cycloconjugation was successfully applied to determine absolute configuration of chiral carboxylic acids. Dinuclear CuII complex of cyclooctapyrrole O2 with interrupted -conjugation was resolved by HPLC into enantiomers and their helical handedness was determined by theoretical simulation of their CD spectral pattern. Enantioselective induction of helicity in the metal helicate formation in the presence of a chiral promoter was demonstrated by using ()-(+)-1-(1-phenyl)ethylamine that favoured , helicity. Dinuclear CoII complexes of cyclotetrapyrroletetrapyridine O3 were found to be substitution labile and pick up amino acid anions in water. Those amino acid complexes of O3Co2 were rendered to adopt a particular unidirectional helical conformation preferentially depending on the ligated amino acid anion.

  15. A primer for chiral perturbation theory

    CERN Document Server

    Scherer, Stefan

    2012-01-01

    Chiral Perturbation Theory, as effective field theory, is a commonly accepted and well established working tool, approximating quantum chromodynamics at energies well below typical hadron masses. This volume, based on a number of lectures and supplemented with additional material, provides a pedagogical introduction for graduate students and newcomers entering the field from related areas of nuclear and particle physics. Starting with the the Lagrangian of the strong interactions and general symmetry principles, the basic concepts of Chiral Perturbation Theory in the mesonic and baryonic sectors are developed. The application of these concepts is then illustrated with a number of examples. A large number of exercises (81, with complete solutions) are included to familiarize the reader with helpful calculational techniques.

  16. New approaches in sensitive chiral CE.

    Science.gov (United States)

    Sánchez-Hernández, Laura; Guijarro-Diez, Miguel; Marina, María Luisa; Crego, Antonio L

    2014-01-01

    CE has shown to have a big potential for chiral separations, with advantages such as high efficiency, high resolution, and low sample and reagents consumption. Nevertheless, when UV detection is employed, CE has some drawbacks, especially the low sensitivity obtained due to the short optical path length. Notwithstanding, sensitivity improvements can be achieved when different approaches are employed, such as sample treatment strategies (off-line or on-line), in-capillary sample preconcentration techniques, and/or alternative detection systems to UV-Vis (such as fluorescence, conductimetry, electrochemiluminiscence, MS, etc.). This article reviews the most recent methodological and instrumental advances reported from June 2011 to May 2013 for enhancing the sensitivity in chiral analysis by CE. The sensitivity achieved for the enantioseparated analytes and the applications carried out using the developed methodologies are also summarized.

  17. Chiral patterning in Paenibacillus colonies under stress

    Science.gov (United States)

    Levine, Herbert

    2012-02-01

    One of the most striking examples of bacterial colony patterning occurs in the C-morphotype of Paenibacillus strains. Here, macroscopic chirality results from the interaction of local liquid-crystal ordering of the long bacterial cells with the self-propelled motility driven by the non-reflection-symmetric flagella. This talk will review some of the original experimental data from the Ben-Jacob lab as well as recent insight obtained via genomics. I will then discuss attempts to model and simulate the chiral patterns via solving reaction-diffusion equations on random lattices. At the end, I will introduce the challenges still to be faced in understanding transitions between these patterns and more common branching structures

  18. Chiral fermions in asymptotically safe quantum gravity

    CERN Document Server

    Meibohm, Jan

    2016-01-01

    We study the consistency of dynamical fermionic matter with the asymptotic safety scenario of quantum gravity using the functional renormalisation group. Since this scenario suggests strongly coupled quantum gravity in the UV, one expects gravity-induced fermion self-interactions at energies of the Planck-scale. These could lead to chiral symmetry breaking at very high energies and thus to large fermion masses in the IR. The present analysis which is based on the previous works \\cite{Christiansen:2015rva, Meibohm:2015twa}, concludes that gravity-induced chiral symmetry breaking at the Planck scale is avoided for a general class of NJL-type models, regardless of the number of fermion flavours. This suggests that the phase diagram for these models is topologically stable under the influence of gravitational interactions.

  19. Chiral perturbation theory with tensor sources

    Energy Technology Data Exchange (ETDEWEB)

    Cata, Oscar; Cata, Oscar; Mateu, Vicent

    2007-05-21

    We construct the most general chirally-invariant Lagrangian for mesons in the presence of external sources coupled to the tensor current \\bar psi sigma_mu nu psi. In order to have only even terms in the chiral expansion, we consider the new source of O(p2). With this choice, we build the even-parity effective Lagrangian up to the p6-order (NLO). While there are only 4 new terms at the p4-order, at p6-order we find 78 terms for n_f=2 and 113 terms for n_f=3. We provide a detailed discussion on the different mechanisms that ensure that our final set of operators is complete and non-redundant. We also examine the odd-parity sector, to conclude that the first operators appear at the p8-order (NNLO).

  20. Chiral Magnetic Effect Task Force Report

    CERN Document Server

    Skokov, Vladimir; Koch, Volker; Schlichting, Soeren; Thomas, Jim; Voloshin, Sergei; Wang, Gang; Yee, Ho-Ung

    2016-01-01

    In this report, we briefly examine the current status of the study of the chiral magnetic effect including theory and experimental progress. We recommend future strategies for resolving uncertainties in interpretation including recommendations for theoretical work, recommendations for measurements based on data collected in the past five years, and recommendations for beam use in the coming years of RHIC. We have specifically investigated the case for colliding nuclear isobars (nuclei with the same mass but different charge) and find the case compelling. We recommend that a program of nuclear isobar collisions to isolate the chiral magnetic effect from background sources be placed as a high priority item in the strategy for completing the RHIC mission.

  1. Chiral closed strings: four massless states scattering amplitude

    Science.gov (United States)

    Leite, Marcelo M.; Siegel, Warren

    2017-01-01

    We compute the scattering amplitudes of four massless states for chiral (closed) bosonic and type II superstrings using the Kawai-Lewellen-Tye ( KLT ) factorization method. The amplitude in the chiral bosonic case is identical to a field theory amplitude corresponding to the spin-2 tachyon, massless gravitational sector and massive spin-2 tardyon states of the spectrum. Chiral type II superstrings amplitude only possess poles associated with the massless gravitational sector. We briefly discuss the extension of the calculation to heterotic superstrings.

  2. Chiral Closed strings: Four massless states scattering amplitude

    CERN Document Server

    Leite, Marcelo M

    2016-01-01

    We compute the scattering amplitudes of four massless states for chiral (closed) bosonic and type II superstrings using the Kawai-Lewellen-Tye ($KLT$) factorization method. The amplitude in the chiral bosonic case is identical to a field theory amplitude corresponding to the spin-$2$ tachyon, massless gravitational sector and massive spin-2 tardyon states of the spectrum. Chiral type II superstrings amplitude only possess poles associated with the massless gravitational sector. We briefly discuss the extension of the calculation to heterotic superstrings.

  3. First molecules, biological chirality, origin(s) of life.

    Science.gov (United States)

    Caglioti, Luciano; Micskei, Károly; Pályi, Gyula

    2011-01-01

    Origin(s) of biological chirality appear(s) to be intimately connected to origin(s) of life. Prebiotic evolution toward these important turning points can be traced back to single chiral molecules. These can be small (monomeric) units as amino acids or monosaccharides or oligomers as oligo-RNA type molecules. Earlier speculations about these two kinds of entries to biological chirality are critically reviewed.

  4. Chirality and anaesthetic drugs: A review and an update

    OpenAIRE

    Sukanya Mitra; Puneet Chopra

    2011-01-01

    Many molecules can exist as right-handed and left-handed forms that are non-superimposable mirror images of each other. They are known as enantiomers or substances of opposite shape. Such compounds are also said to be chiral (Greek chiros meaning ‘hand’). Such chiral molecules are of great relevance to anaesthetic theory and practice. This review summarizes the basic concepts, pharmacokinetic and pharmacodynamic aspects of chirality, and some specific examples of their application in anaesthe...

  5. Microstructure Effects for Casimir Forces in Chiral Metamaterials

    OpenAIRE

    McCauley, Alexander P.; Zhao, Rongkuo; Reid, M. T. Homer; Rodriguez, Alejandro W.; Zhou, Jiangfeng; Rosa, F. S. S.; Joannopoulos, John D; Dalvit, D. A. R.; Soukoulis, Costas M.; Johnson, Steven G.

    2010-01-01

    We examine a recent prediction for the chirality-dependence of the Casimir force in chiral metamaterials by numerical computation of the forces between the exact microstructures, rather than homogeneous approximations. We compute the exact force for a chiral bent-cross pattern, as well as forces for an idealized "omega"-particle medium in the dilute approximation and identify the effects of structural inhomogeneity (i.e. proximity forces and anisotropy). We find that these microstructure effe...

  6. Chiral condensate, susceptibilities, critical coupling and indices in QED$_{4}$

    CERN Document Server

    Azcoiti, V; Galante, A; Grillo, A F; Laliena, V; Piedrafita, C E

    1995-01-01

    We measure chiral susceptibilities in the Coulomb phase of noncompact QED_4 in 8^4, 10^4 and 12^4 lattices. The MFA approach allows simulations in the chiral limit which are therefore free from arbitrary mass extrapolations. Using the critical couplings extracted from these calculations, we study the critical behaviour of the chiral condensate, which we find in disagreement with the predictions of logarithmically improved scalar Mean Field theory.

  7. Simultaneous Chiral SeparationUsing a Combinatorial Molecular Imprinting Phase

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Molecular imprinting chiral stationary phase against Cbz-L-Serine (Cbz-L-Ser) and Cbz-L-Alaine (Cbz-L-Ala) were prepared utilizing acrylamide + 2-vinylpyridine as combined basic functional monomers.Cross-selectivity was used to obtain simultaneous chiral separations of Cbz-DL-Ser and Cbz-DL-Ala by connecting two columns packed with Cbz-L-Ser and Cbz-L-Ala imprinted chiral stationary phase, respectively.

  8. Nanoconfinement-Induced Structures in Chiral Liquid Crystals

    OpenAIRE

    2013-01-01

    We employ Monte Carlo simulations in a specialized isothermal-isobaric and in the grand canonical ensemble to study structure formation in chiral liquid crystals as a function of molecular chirality. Our model potential consists of a simple Lennard-Jones potential, where the attractive contribution has been modified to represent the orientation dependence of the interaction between a pair of chiral liquid-crystal molecules. The liquid crystal is confined between a pair of planar and atomicall...

  9. Chiral deformations of conformal field theories

    Science.gov (United States)

    Dijkgraaf, Robbert

    1997-02-01

    We study general perturbations of two-dimensional conformal field theories by holomorphic fields. It is shown that the genus one partition function is controlled by a contact term (pre-Lie) algebra given in terms of the operator product expansion. These models have applications to vertex operator algebras, two-dimensional QCD, topological strings, holomorphic anomaly equations and modular properties of generalized characters of chiral algebras such as the W1+∞ algebra, that is treated in detail.

  10. Chiral Deformations of Conformal Field Theories

    CERN Document Server

    Dijkgraaf, R

    1996-01-01

    We study general perturbations of two-dimensional conformal field theories by holomorphic fields. It is shown that the genus one partition function is controlled by a contact term (pre-Lie) algebra given in terms of the operator product expansion. These models have applications to vertex operator algebras, two-dimensional QCD, topological strings, holomorphic anomaly equations and modular properties of generalized characters of chiral algebras such as the $W_{1+\\infty}$ algebra, that is treated in detail.

  11. Chiral deformations of conformal field theories

    Energy Technology Data Exchange (ETDEWEB)

    Dijkgraaf, R. [Amsterdam Univ. (Netherlands). Dept. of Math.

    1997-06-02

    We study general perturbations of two-dimensional conformal field theories by holomorphic fields. It is shown that the genus one partition function is controlled by a contact term (pre-Lie) algebra given in terms of the operator product expansion. These models have applications to vertex operator algebras, two-dimensional QCD, topological strings, holomorphic anomaly equations and modular properties of generalized characters of chiral algebras such as the W{sub 1+{infinity}} algebra, that is treated in detail. (orig.).

  12. Chiral Deformations of Conformal Field Theories

    OpenAIRE

    Dijkgraaf, R.

    1996-01-01

    We study general perturbations of two-dimensional conformal field theories by holomorphic fields. It is shown that the genus one partition function is controlled by a contact term (pre-Lie) algebra given in terms of the operator product expansion. These models have applications to vertex operator algebras, two-dimensional QCD, topological strings, holomorphic anomaly equations and modular properties of generalized characters of chiral algebras such as the $W_{1+\\infty}$ algebra, that is treat...

  13. Chiral Symmetry restoration from the hadronic regime

    CERN Document Server

    Nicola, Angel Gomez; Morales, John; de Elvira, Jacobo Ruiz; Andres, Ricardo Torres

    2016-01-01

    We discuss recent advances on QCD chiral symmetry restoration at finite temperature, within the theoretical framework of Effective Theories. $U(3)$ Ward Identities are derived between pseudoscalar susceptibilities and quark condensates, allowing to explain the behaviour of lattice meson screening masses. Unitarized interactions and the generated $f_0(500)$ thermal state are showed to play an essential role in the description of the transition through the scalar susceptibility

  14. Synthesis of Resins with Chiral Salen Complexes

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@ The enormous growth in the use of polymer resin supports in solid phase combinatorial synthesis, and related methodologies, has re-stimulated interest in the area of polymer-supported transition metal complex catalyst .The recently developed chiral salen-based for the enantioselective ring opening of meso epoxides and kinetic resolution of terminal epoxides are appealing candidates for immobilization on solid support. The catalysts are reading prepare from inexpensive components, and are amenable to modification for attachment to a solid support.

  15. Anomalous CMB polarization and gravitational chirality

    OpenAIRE

    Contaldi, Carlo R.; Magueijo, Joao; Smolin, Lee

    2008-01-01

    We consider the possibility that gravity breaks parity, with left and right handed gravitons coupling to matter with a different Newton's constant and show that this would affect their zero-point vacuum fluctuations during inflation. Should there be a cosmic background of gravity waves, the effect would translate into anomalous CMB polarization. Non-vanishing TB (and EB) polarization components emerge, revealing interesting experimental targets. Indeed if reasonable chirality is present a TB ...

  16. Stern-Gerlach effect goes chiral

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ Prof. SUN Changpu from the CAS Institute of Theoretical Physics and coworkers from University of Basel in Switzerland have worked out a way - at least in theory - to split a beam of molecules according to their chirality. The technique involves passing the molecules through three different laser beams and is similar to the famous Stern-Gerlach effect, whereby a beam of atoms passing through a magnetic field is split in two according to the atoms' spin states (Phys. Rev. Lett. 99 130403).

  17. Chiral Biomarkers and Microfossils in Carbonaceous Meteorites

    Science.gov (United States)

    Hoover, Richard B.

    2010-01-01

    Homochirality of the biomolecules (D-sugars of DNA and RNA and L-amino acids of proteins) is a fundamental property of all life on Earth. Abiotic mechanisms yield racemic mixtures (D/L=1) of chiral molecules and after the death of an organism, the enantiopure chiral biomolecules slowly racemize. Several independent investigators have now established that the amino acids present in CI1 and CM2 carbonaceous meteorites have a moderate to strong excess of the L-enantiomer. Stable isotope data have established that these amino acids are both indigenous and extraterrestrial. Carbonaceous meteorites also contain many other strong chemical biomarkers including purines and pyrimidines (nitrogen heterocycles of nucleic acids); pristine and phytane (components of the chlorophyll pigment) and morphological biomarkers (microfossils of filamentous cyanobacteria). Energy dispersive X-ray Spectroscopy (EDS) analysis reveals that nitrogen is below the detectability level in most of the meteorite filaments as well as in Cambrian Trilobites and filaments of 2.7 Gya Archaean cyanobacteria from Karelia. The deficiency of nitrogen in the filaments and the total absence of sugars, of twelve of the life-critical protein amino acids, and two of the nucleobases of DNA and RNA provide clear and convincing evidence that these filaments are not modern biological contaminants. This paper reviews the chiral, chemical biomarkers morphological biomarkers and microfossils in carbonaceous meteorites. This paper reviews chiral and morphological biomarkers and discusses the missing nitrogen, sugars, protein amino acids, and nucleobases as ?bio-discriminators? that exclude modern biological contaminants as a possible explanation for the permineralized cyanobacterial filaments found in the meteorites.

  18. Chiral benzimidazoles as hydrogen bonding organocatalysts

    OpenAIRE

    Nájera Domingo, Carmen; Yus Astiz, Miguel

    2015-01-01

    Several bifunctional organocatalysts bearing the benzimidazole unit have been designed in order to act as bifunctional systems by hydrogen bonding. Chiral 2-aminobenzimidazoles are conformational rigid guanidines able to catalyze enantioselectively Michael reaction, direct SN1 of alcohols, and aldol reactions. Some of these organocatalysts can be easily recovered by simple isolation methods and reused without loss of catalytic activity. Related (2-aminoalkyl)benzimidazoles have been used as c...

  19. Chiral random matrix theory for staggered fermions

    CERN Document Server

    Osborn, James C

    2012-01-01

    We present a completed random matrix theory for staggered fermions which incorporates all taste symmetry breaking terms at their leading order from the staggered chiral Lagrangian. This is an extension of previous work which only included some of the taste breaking terms. We will also discuss the effects of taste symmetry breaking on the eigenvalues in the weak and strong taste breaking limits, and compare with some results from lattice simulations.

  20. Chiral unitary theory: Application to nuclear problems

    Indian Academy of Sciences (India)

    E Oset; D Cabrera; H C Chiang; C Garcia Recio; S Hirenzaki; S S Kamalov; J Nieves; Y Okumura; A Ramos; H Toki; M J Vicente Vacas

    2001-08-01

    In this talk we briefly describe some basic elements of chiral perturbation theory, , and how the implementation of unitarity and other novel elements lead to a better expansion of the -matrix for meson–meson and meson–baryon interactions. Applications are then done to the interaction in nuclear matter in the scalar and vector channels, antikaons in nuclei and - atoms, and how the meson properties are changed in a nuclear medium.