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Sample records for central tipo iv

  1. High serum laminin and type IV collagen levels in schistosomiasis mansoni Elevação dos níveis séricos de laminina e colágeno tipo IV na esquistossomose mansoni

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    Rozangela Maria de Almeida Fernandes Wyszomirska

    2005-12-01

    Full Text Available BACKGROUND: Fibrosis is the process of excessive deposition of collagen and other extra cellular matrix components and large amounts of these components have been shown in periovular schistosomal granulomas, especially in the liver. Laminin and type IV collagen have been investigated in various hepatic disorders but their accuracy in fibrosis detection and in the evaluation of its progression in schistosomiasis have not been fully explained. AIM: To measure the serum levels of two markers of fibrosis, laminin and type IV collagen in schistosomiasis. PATIENTS AND METHODS: Sixty-four patients with different clinical forms of schistosomiasis mansoni: intestinal (group I, hepatointestinal (group II, compensated (group III and decompensated hepatosplenic (group IV and 18 healthy volunteers were included. RESULTS: Serum type IV collagen and laminin levels were significantly increased in patients compared to controls. At about clinical forms, serum type IV collagen was increased in groups II and IV, compared to controls and was significantly higher in group IV than in group I. Serum laminin was significantly increased in groups II, III and IV and was significantly higher in group IV than in group II. Serum type IV collagen was closely correlated with serum laminin in groups II and IV. CONCLUSIONS: Connective tissue marker levels did not correlate with periportal thickness. In schistosomiasis mansoni there is an increase of type IV collagen and laminin levels at the initial stage of the disease, as well as in advanced forms. We also suggest that these markers may be a useful predictor of disease progression.RACIONAL: A fibrose hepática é caracterizada por um aumento progressivo na quantidade do tecido conjuntivo hepático, que é formado pelo aumento na deposição de componentes da matriz extracelular, tendo sido encontrada grande quantidade desses componentes no fígado de pacientes com esquistossomose mansoni. A laminina e o colágeno tipo IV t

  2. Adaptabilidade e estabilidade de genótipos de girassol no Brasil Central Adaptability and stability of sunflower genotypes in Central Brazil

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    Anna Karolina Grunvald

    2008-11-01

    Full Text Available O objetivo deste trabalho foi avaliar a adaptabilidade e estabilidade de genótipos de girassol, no Brasil Central, quanto ao rendimento de grãos e de óleo. Os dados foram obtidos de ensaios de genótipos de girassol coordenados pela Embrapa Soja, de 2004 a 2007. Foram usados os métodos de Eberhart & Russell, Porto et al., Rocha et al. e Annicchiarico. Foi realizada a decomposição do índice de recomendação de Annicchiarico nos ambientes favoráveis e desfavoráveis. Este método e o de Porto et al. foram similares e mais adequados para avaliar a adaptabilidade dos genótipos. Em relação ao rendimento de grãos, as variedades BRSGira 02 e Nutrissol apresentaram adaptação ampla. Os híbridos Agrobel 959, MG50 e V03005 e as variedades Catissol e Multissol apresentaram adaptação aos ambientes favoráveis, e os híbridos BRHS 02 e BRHS 04 apresentaram adaptação aos ambientes desfavoráveis. Quanto ao rendimento de óleo, os híbridos Agrobel 959, V03005, MG50, VDH 487, EXP 1441, EXP 1447 e EXP 1446 e as variedades BRSGira 01, BRSGira 02 e Nutrissol apresentaram adaptação ampla. O híbrido MG52 e as variedades Catissol e Multissol mostraram adaptação aos ambientes favoráveis, e BRHS 04 e BRHS 02 mostraram adaptação aos ambientes desfavoráveis. Os genótipos selecionados mostraram-se estáveis, mas em níveis diferenciados.The objective of this study was to evaluate the adaptability and stability of sunflower genotype grain and oil yield, in Central Brazil. The analyzed data were obtained from sunflower genotype trials coordinated by Embrapa Soja, from 2004 to 2007. Genotype adaptability and stability were evaluated using the methods of Eberhart & Russell, Porto et al., Rocha et al., and Annicchiarico. The Annicchiarico method divides sites into favorable and unfavorable environments. This method and the one of Porto et al. were similar and more adequate to evaluate genotypic adaptability. For grain yield, the varieties BRSGira

  3. Central administration of angiotensin IV rapidly enhances novel object recognition among mice.

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    Paris, Jason J; Eans, Shainnel O; Mizrachi, Elisa; Reilley, Kate J; Ganno, Michelle L; McLaughlin, Jay P

    2013-07-01

    Angiotensin IV (Val(1)-Tyr(2)-Ile(3)-His(4)-Pro(5)-Phe(6)) has demonstrated potential cognitive-enhancing effects. The present investigation assessed and characterized: (1) dose-dependency of angiotensin IV's cognitive enhancement in a C57BL/6J mouse model of novel object recognition, (2) the time-course for these effects, (3) the identity of residues in the hexapeptide important to these effects and (4) the necessity of actions at angiotensin IV receptors for procognitive activity. Assessment of C57BL/6J mice in a novel object recognition task demonstrated that prior administration of angiotensin IV (0.1, 1.0, or 10.0, but not 0.01 nmol, i.c.v.) significantly enhanced novel object recognition in a dose-dependent manner. These effects were time dependent, with improved novel object recognition observed when angiotensin IV (0.1 nmol, i.c.v.) was administered 10 or 20, but not 30 min prior to the onset of the novel object recognition testing. An alanine scan of the angiotensin IV peptide revealed that replacement of the Val(1), Ile(3), His(4), or Phe(6) residues with Ala attenuated peptide-induced improvements in novel object recognition, whereas Tyr(2) or Pro(5) replacement did not significantly affect performance. Administration of the angiotensin IV receptor antagonist, divalinal-Ang IV (20 nmol, i.c.v.), reduced (but did not abolish) novel object recognition; however, this antagonist completely blocked the procognitive effects of angiotensin IV (0.1 nmol, i.c.v.) in this task. Rotorod testing demonstrated no locomotor effects with any angiotensin IV or divalinal-Ang IV dose tested. These data demonstrate that angiotensin IV produces a rapid enhancement of associative learning and memory performance in a mouse model that was dependent on the angiotensin IV receptor.

  4. Número, tipo e topografia dos pontos de vazamento em pacientes com coriorretinopatia serosa central Number, shape, and topography of leakage points in patients with central serous chorioretinopathy

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    Remo Turchetti

    2005-06-01

    Full Text Available OBJETIVO: Avaliar o número, forma e topografia dos pontos de vazamento em pacientes com coriorretinopatia serosa central (CRSC. MÉTODOS: Foram avaliados exames de angiografia fluoresceínica realizados utilizando o sistema digital Imagenet e selecionados os casos com diagnóstico de CRSC. Foram excluídos os casos em remissão e os exames referentes a um mesmo episódio. O autor preencheu fichas contendo o número do prontuário, iniciais, sexo, idade, data do exame e características do ponto de vazamento (número, localização e tipo dos casos selecionados. RESULTADOS: Foram incluídos 418 pacientes (455 olhos, com uma relação homem:mulher de 2,32:1, sendo que 91,15% dos pacientes apresentaram a doença unilateralmente e 8,85%, bilateralmente. A idade variou de 19 a 68 anos, com média de 43,04 anos. Dos 455 olhos acometidos, 88,35% apresentaram a forma típica de CRSC, enquanto 10,11% a descompensação do epitélio pigmentário da retina (DEPR e 1,54% com descolamento isolado do epitélio pigmentário da retina (EPR. Entre os casos de CRSC típica, observaram-se 88,81% dos pontos de vazamento em "mancha de tinta" e 11,19% em "chaminé". O quadrante nasal superior foi o mais acometido, abrigando 46,01% dos pontos de vazamento, seguido pelo temporal superior (23,27%, nasal inferior (19,18%, temporal inferior (11,01% e região subfoveal (0,53%. CONCLUSÕES: Na nossa casuística, a CRSC acometeu aproximadamente duas vezes mais homens que mulheres, na maior parte das vezes unilateralmente e em pacientes da 4ª década de vida. Cerca de 90% dos pacientes apresentaram a forma típica da doença, com 1 ou 2 pontos de vazamento em "mancha de tinta". O quadrante nasal superior foi o mais acometido. O descolamento isolado do EPR mostrou-se apresentação rara. Cerca de 10% dos pacientes apresentaram descompensação do EPR.PURPOSE: To evaluate the number, shape and topography of leakage points in patients with central serous chorioretinopathy (CSC

  5. Avaliação do tipo de curativo utilizado em cateter venoso central para hemodiálise Evaluación del tipo de curativo utilizado en cateter venoso central para hemodiálisis Evaluation of tow types of dressings used on central venous catheters for hemodialysis

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    Luciene de Fátima Neves Monteiro de Barros

    2009-01-01

    Full Text Available OBJETIVOS: Avaliar a efetividade de dois tipos de curativos utilizados em cateter venoso central (CVC em pacientes submetidos à hemodiálise; identificar a taxa de infecção no local de saída e de bacteremia comparando o curativo com gaze e micropore em relação ao filme transparente. MÉTODOS: Foi realizado um ensaio clínico randomizado controlado abrangendo 66 pacientes, sendo 33 nos grupos 1 e 2, respectivamente. No Grupo 1 o curativo utilizado foi gaze e micropore e no Grupo 2 filme transparente. Foram coletados os dados sócio demográficos, clínicos e os relacionados às infecções. Os 66 pacientes permaneceram no estudo até a indicação de retirada do cateter que ocorreu nos episódios de infecção quando foram realizadas culturas de óstio e da ponta do CVC e hemocultura quando indicado. RESULTADOS: Não houve diferença estatística significante quanto ao tipo de curativo e as variáveis estudadas. Os CVC posicionados a 90º em relação a pele apresentaram maior taxa de infecção por S. aureus. CONCLUSÃO: O uso do filme transparente não proporcionou redução de infecção, porém a análise qualitativa deste tipo de curativo teve melhor aceitação pelos pacientes e profissionais da Unidade de Diálise de um Hospital Universitário.OBJETIVOS: Evaluar la efectividad de dos tipos de curativos utilizados en cateter venoso central (CVC en pacientes submetidos al hemodiálisis; identificar el índice de infección en el local de salida y de bacteremia comparando el curativo con gaza y micropore el con al filme transparente. MÉTODOS: Fue realizado un ensayo clínico randomizado controlado. En el Grupo 1 el curativo utilizado fue gaza y micropore y en el Grupo 2 filme transparente. Fueron colectados los datos sócio demográficos, clínicos y los relacionados a las infecciones. Los 66 pacientes permanecieron en el estudio hasta la indicación de retirada del cateter que ocurrió en los episodios de infección cuando fueron

  6. Estabilidade dimensional dos moldes de poliéter e polissulfeto obtidos com a técnica do casquete de acrílico, vazados em gesso pedra especial tipo IV e V = Dimensional stability of polyether and polysulfide impression materials obtained with acrylic coping techniques pouring in stone type IV and V

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    Alves, Maria Cechinel

    2005-01-01

    Full Text Available O propósito deste estudo foi verificar o comportamento de moldes de polissulfeto (Permlastic e poliéter (Impregum Soft obtidos por meio da técnica do casquete de resina acrílica. Avaliou-se a estabilidade dimensional dos moldes confeccionados de uma matriz metálica contendo dois preparos protéticos, com diâmetros e alturas diferentes. Os moldes de cada material foram vazados com gessos pedra IV (Vel-mix e gesso pedra V (Exadur, perfazendo um total de quatro combinações experimentais: (polissulfeto/gesso-pedra IV, polissulfeto/gesso-pedra V, poliéter/gesso-pedra IV e poliéter/gesso-pedra V. Os troquéis de gesso foram mensurados com um paquímetro digital, 24 horas após sua obtenção. Os resultados obtidos foram submetidos a ANOVA a 5%. Pode-se concluir que os moldes de poliéter vazados com gesso pedra tipo V apresentaram melhor estabilidade dimensional em relação às outras condições experimentais

  7. Central nervous system infection caused by vancomycin-intermediate Staphylococcus aureus (SCCmec type IV, ST8).

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    Kino, Hiroyoshi; Suzuki, Hiromichi; Yamaguchi, Tetsuo; Notake, Shigeyuki; Oishi, Tsuyoshi; Ito, Yoshiro; Nakamura, Kazuhiro; Miyazaki, Haruko; Matsumoto, Tetsuya; Uemura, Kazuya; Matsumura, Akira

    2014-10-01

    A 77-year-old Japanese man with a history of surgical treatment of chronic subdural hemorrhage was hospitalized for drainage of a subdural abscess and brain abscess in the right occipital area. Pus obtained from both the subdural abscess and brain abscess grew vancomycin-intermediate Staphylococcus aureus (VISA) (minimum inhibitory concentration = 4 μg/mL), which was confirmed by population analysis. The SCCmec type and sequence type were subsequently identified as IV and ST8, respectively. The VISA strains were both sensitive to levofloxacin, clindamycin, minocycline, and linezolid. The patient was successfully treated with linezolid and discharged on day 51 after admission. We herein describe the first reported case of a brain abscess and subdural abscess caused by VISA in Japan.

  8. Key locations for soybean genotype assessment in Central Brazil Locais-chave para avaliação de genótipos de soja na Região Central do Brasil

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    Roberto Miranda Pacheco

    2009-05-01

    Full Text Available The objective of this work was to identify key locations for the establishment of soybean (Glycine max genetic breeding programs, in the Central Region of Brazil. Grain yield data of three maturity groups of soybean genotypes, from regional trials conducted over three years, at 18 locations in Brazilian Cerrado were used. A key location for the early phases of the breeding program was defined as the site that best classifies the winning genotypes in the region. Key locations for the final phases were defined as those sites that best represent each environmental stratum, in relation to the adaptability of the respective winning genotype. This adaptability was estimated by additive main effects and multiplicative interaction (AMMI model analysis, using the distance between the score of each location in a stratum and the score of the winning genotype, which characterizes such stratum in an AMMI biplot. The locations that best classified the winning genotypes over space and time were Mineiros, Placas and Rio Verde. For the final phases of genotype selection, with data from the three maturity group, the recommended locations were: Buritis, Chapadão do Céu, Iraí, Pamplona, Placas, Planaltina, Rio Verde, Sacramento, Senador Canedo, Uberaba, and Uberlândia.O objetivo deste trabalho foi identificar locais-chave para o estabelecimento de programas de melhoramento genético de soja (Glycine max, na Região Central do Brasil. Foram utilizados dados de produtividade de grãos de genótipos de soja, de três ciclos de maturação, obtidos de ensaios regionais conduzidos por três anos em 18 localidades da região. O local-chave para a condução das fases preliminares do programa foi definido como a localidade que melhor classifica os genótipos vencedores na região. Os locais-chave para as fases finais foram definidos como os que melhor representam cada estrato ambiental identificado, em termos da adaptabilidade do respectivo genótipo vencedor. Essa

  9. Evaluación de la calidad del riego en máquinas eléctricas de pivote central del modelo o tipo Ballama"

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    Norge Tornés O

    2009-01-01

    Full Text Available El trabajo se realizó en áreas regadas con la máquina eléctrica de pivote central tipo Ballama de 8 torres, en un suelo aluvial poco diferenciado cultivado de papa en la Unidad Básica de Producción Cooperativa (UBPC "Antonio Maceo", de la Empresa de Cultivos Varios "Paquito Rosales", ubicada en el poblado de Veguitas, municipio Yara, provincia Granma. El experimento se desarrolló en el período de diciembre de 2005 a marzo de 2006, El marco de siembra utilizado fue: 0,90 m entre hileras y 0,25m entre plantas. El análisis de la lluvia a lo largo de la máquina arrojó una distribución no uniforme, semejante comportamiento presentó la altura por planta obteniéndose los menores valores en tramos de valor del coeficiente de uniformidad.

  10. Novas técnicas cirúrgicas para o tratamento da atresia pulmonar com comunicação interventricular e anomalias de artérias pulmonares incluindo o assim chamado truncus tipo IV New surgical techniques for treatment of pulmonary atresia with ventricular septal defect and pulmonary arteries anomalies including the so-called tipo IV truncus

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    Miguel Barbero-Marcial

    1987-04-01

    Full Text Available Entre janeiro de 1975 e outubro de 1986, 42 pacientes com atresia pulmonar e comunicação interventricular, com idade entre 2 e 18 anos, foram submetidos a correção parcial, ou total. Foram divididos em: tipo A com todos os segmentos broncopulmonares conectados às artérias pulmonares (AP's, 34 pacientes; tipo B com alguns dos segmentos broncopulmonares conectados às AP's, 6 pacientes; tipo C com todos os segmentos broncopulmonares conectados às colaterais sistêmico-pulmonares, 2 pacientes. A correção foi planejada em uma a três etapas. No tipo A, 17 foram corrigidos em uma etapa, com três óbitos; em 9, na primeira etapa, as AP's foram reconstruídas e o Blalock (BT, realizado, tendo ocorrido um óbito. Em 2, a segunda etapa de correção total foi realizada, sem óbitos. No tipo B, a primeira etapa de unificação das colaterais intra ou extra-hilares foi realizada em 6 casos, sem óbitos; em 2, a segunda etapa da correção total foi realizada, com um óbito. No tipo C, 2 pacientes foram operados; 1 em três etapas; a primeira constou de construção de segmento arterial intermediário entre as artérias lobares e o BT; a segunda compreendeu unificação das colaterais contralaterais e a terceira, restabelecimento da continuidade ventrículo direito - circulação pulmonar; o paciente teve boa evolução. No segundo caso, a correção foi realizada após somente uma intervenção prévia. A evolução foi satisfatória. Estudos hemodinâmicos seriados foram realizados em 32 pacientes. As técnicas propostas permitem obter condições para correção total com adequada relação pós-operatória das pressões ventrículo direito - ventrículo esquerdo.Fourty-two patients with pulmonary atresia and interventricular septal defect were submited to a partial or total correction, between January 1975 and October 1986, with a range of 2 months to 18 years of age. Three groups were identified: Group A: 34 patients with all bronco

  11. Fibroma odontogénico central, tipo WHO: Reporte de un caso y revisión de la literatura Central odontogenic fibroma, WHO type: A case report and literature review

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    Carla Muñoz Torres

    2010-12-01

    Full Text Available El fibroma odontogénico central es una neoplasia benigna muy poco frecuente. Clásicamente se ha dividido en dos variantes histológicas: un tipo pobre en epitelio y otro tipo rico en epitelio con focos de material calcificado. En la mayoría de los casos muestra un crecimiento lento y progresivo con o sin sintomatología. Radiográficamente es habitual observar una imagen radiolúcida y unilocular que en raras ocasiones exhibe radiolucidez mixta. El tratamiento indicado en todos los casos es la enucleación del tumor. Se reporta el caso de una mujer de 36 años de edad, sin antecedentes mórbidos, con una lesión asintomática de radiolucidez mixta, expansiva de ambas corticales óseas, en la zona del cuerpo y ángulo mandibular izquierdo, asociada a un tercer molar incluido. Basándose en el estudio histopatológico inicial, se diagnosticó como fibroma odontogénico, y con el posterior tratamiento definitivo de la lesión, se determinó la subvariedad tipo OMS. La paciente no ha tenido recidiva en 16 meses de seguimiento.The central odontogenic fibroma is a rare benign neoplasm. Classically has been divided into two histological variants, a poor type epithelium and other rich epithelium with foci of calcified material. It shows in most cases, a slow and progressive growing with or without symptoms. Radiographically it is common to observe a radiolucent, unilocular, rarely exhibiting mixed radiolucency. The treatment in all cases is enucleation of the tumor. We report the case of a 36 year old woman, no morbid history, with an asymptomatic lesion of mixed radiolucency, cortical bone expansion in the area of the body and the left mandibular angle associated with a third molar. Based on the initial histopathology it was diagnosed as odontogenic fibroma and subsequent definitive treatment of the injury rate was determined sub manifold WHO. The patient had no recurrence at 16 months of follow-up.

  12. Múltiplas hiperintensidades no sistema nervoso central em uma criança com neurofibromatose do tipo 1 Multiple central nervous system hyperintensities in a child with neurofibromatosis type 1

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    Carla Graziadio

    2011-12-01

    Full Text Available OBJETIVO: Relatar o caso de uma criança com neurofibromatose do tipo 1, apresentando o achado ocasional de múltiplas hiperintensidades e de lesão hamartomatosa pré-quiasmática no sistema nervoso central. DESCRIÇÃO DO CASO: Menino de tez escura de quatro anos, cujo pai apresentava manchas café-com-leite e história de cirurgia de tumor de ouvido. A criança evoluiu com um adequado desenvolvimento neuropsicomotor, sem crises convulsivas ou déficit de aprendizagem. Ao exame físico, possuía múltiplas manchas café-com-leite e efélides. A avaliação pela ressonância nuclear magnética de encéfalo evidenciou múltiplas imagens nodulares hiperintensas em T2 e Flair, com isossinal em T1, localizadas na substância branca dos hemisférios cerebrais, cerebelo e tronco cerebral. Apresentava ainda lesão hamartomatosa pré-quiasmática. A avaliação eletroencefalográfica e o exame neurológico eram normais. COMENTÁRIOS: As imagens hiperintensas verificadas na ressonância nuclear magnética correspondem aos chamados unidentified bright objects (UBOs, observados em de 60 a 70% das crianças com neurofibromatose do tipo 1, sendo raros em adultos. Sua etiologia e significado clínico ainda não são claros. Alguns estudos os têm associado à disfunção cognitiva, déficit neurológico e risco de malignização. Hamartomas localizados próximos ao quiasma óptico são incomuns, mas podem se relacionar à puberdade precoce. A avaliação do sistema nervoso central de crianças assintomáticas com neurofibromatose do tipo 1 é discutível. Contudo, nos casos em que UBOs sejam identificados, é importante considerar seu seguimento radiológico, especialmente diante de lesões múltiplas ou atípicas.OBJECTIVE:To report a child with neurofibromatosis type 1 presenting the occasional central nervous system feature of multiple hyperintensities and a prechiasmatic hamartomatous lesion. CASE DESCRIPTION: The patient is a four-year old black boy

  13. Fratura extra-articular da extremidade medial da clavícula associada à luxação acromioclavicular tipo IV: relato de caso Extra-articular fracture of the medial end of the clavicle associated with type IV acromioclavicular dislocation: case report

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    Mário Chaves Correa

    2011-10-01

    Full Text Available Ocorrendo isoladamente, as fraturas da clavícula e as luxações acromioclaviculares são lesões muito comuns. A combinação de uma luxação acromioclavicular e de uma fratura do terço lateral da clavícula não é rara. Entretanto, existem muito poucos casos descritos de luxações acromioclaviculares associadas a fraturas do terço médio da clavícula; aquelas associadas a fraturas do terço medial são ainda mais raras. Nós reportamos o caso de um indivíduo adulto do sexo masculino que sofreu uma luxação acromioclavicular (tipo IV associada a uma fratura extra-articular desviada da extremidade medial da clavícula (grupo 3 de Almann em um acidente ciclístico. O paciente foi tratado na fase aguda com redução aberta e fixação interna das duas lesões. Na avaliação clínica, 12 meses após a cirurgia, o paciente apresentava-se assintomático, com mobilidade ativa e passiva completa, força e resistência normais e simetria das cinturas escapulares. As radiografias e a tomografia computadorizada tridimensional mostravam subluxação posterossuperior persistente da articulação acromioclavicular e consolidação anatômica da fratura clavicular.Fractures of the clavicle and acromioclavicular dislocations are very common injuries when they occur separately. The combination of an acromioclavicular dislocation and a fracture of the lateral third of the clavicle is not rare. However, there are very few reported cases of acromioclavicular dislocations associated with fractures of the middle third of the clavicle; those associated with fractures of the medial third are even rarer. We report the case of an adult male who suffered an acromioclavicular dislocation (type IV associated with a displaced extra-articular fracture of the medial end of the clavicle (Almann group 3 in a cycling accident. The patient was treated during the acute phase with open reduction and internal fixation of the two lesions. At the clinical evaluation 12

  14. Specialized consultant in radiological safety to the south central hospital of high speciality, PEMEX. IV. - October of 2001; Asesoria especializada en seguridad radiologica a la clinica al hospital central sur de alta especialidad, PEMEX. IV.- Octubre de 2001

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    Angeles C, A.; Vizuet G, J.; Benitez S, J. A.; Garcia A, J.; Rodriguez A, F

    2002-01-15

    The south central hospital of high speciality, dependent of PEMEX, It request consultant of the ININ to be able to maintain their sanitary license for the use of X-ray equipment for the radiologic diagnostic.The proposal of the ININ was to be a program of technical attendance, schedule monthly to be able to solve the observations that are presented in the use of those equipment, and that the hospital can conserve its respective sanitary license.(Author)

  15. Specialized consultant in radiological safety to the clinical north central hospital of high speciality, PEMEX. IV. - December of 2001; Asesoria especializada en seguridad radiologica a la clinica hospital central norte de alta especialidad, PEMEX. IV.- Diciembre de 2001

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    Angeles C, A.; Vizuet G, J.; Benitez S, J. A.; Garcia A, J.; Rodriguez A, F

    2002-01-15

    The clinical north central hospital of high speciality, dependent of PEMEX, It request consultant of the ININ to be able to maintain their sanitary license for the use of X-ray equipment for the radiologic diagnostic.The proposal of the ININ was to be a program of technical attendance, schedule monthly to be able to solve the observations that are presented in the use of those equipment, and that the hospital can conserve its respective sanitary license.(Author)

  16. Model of automatic fuel management for the Atucha II nuclear central with the PUMA IV code; Modelo de gestion automatica de combustible para la Central Nuclear Atucha II con el codigo PUMA IV

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    Marconi G, J.F.; Tarazaga, A.E.; Romero, L.D. [CNEA, Av. Gral. Paz 1499 San Martin-Bs. As. (Argentina)]. e-mail: marconi@cnea.gov.ar

    2007-07-01

    The Atucha II central is a heavy water power station and natural uranium. For this reason and due to the first floor reactivity excess that have this type of reactors, it is necessary to carry out a continuous fuel management and with the central in power (for the case of Atucha II every 0.7 days approximately). To maintain in operation these centrals and to achieve a good fuels economy, different types of negotiate of fuels that include areas and roads where the fuels displace inside the core are proved; it is necessary to prove the great majority of these managements in long periods in order to corroborate the behavior of the power station and the burnt of extraction of the fuel elements. To carry out this work it is of great help that a program implements the approaches to continue in each replacement, using the roads and areas of each administration type to prove, and this way to obtain as results the one regulations execution in the time and the average burnt of extraction of the fuel elements, being fundamental this last data for the operator company of the power station. To carry out the previous work it is necessary that a physicist with experience in fuel management proves each one of the possible managements, even those that quickly can be discarded if its don't fulfill with the regulatory standards or its possess an average extraction burnt too much low. For this it is of fundamental help that with an automatic model the different administrations are proven and lastly the physicist analyzes the more important cases. The pattern in question not only allows to program different types of roads and areas of fuel management, but rather it also foresees the possibility to disable some of the approaches. (Author)

  17. Efeito de frações peptídicas do veneno da serpente Bothrops jararaca (Serpentes, Viperidae: Crotalinae) sobre a atividade enzimática dipeptidil-peptidase IV (DPP-IV) e sobre o receptor (GLP-1R) do peptídeo glucagon-símile tipo 1 (GLP-1).

    OpenAIRE

    Leonardo Zambotti Villela

    2010-01-01

    Novos agentes terapêuticos que preservem as células β do pâncreas e o controle do peso são importantes para o diabetes melittus tipo 2 (DM-2), constituindo uma importante área de investimento farmacêutico. Com o objetivo de contribuir com a toxinologia comparada de venenos de répteis e com a eventual descoberta de novos agentes insulinotrópicos, o presente estudo realizou a prospecção de compostos hipoglicemiantes análogos à exendina-4 (isolada de lagartos Heloderma) ou inibidores da dipe...

  18. TIPO TOTAL DE INJUSTO

    OpenAIRE

    Guimarães, Rodrigo Suzana

    2008-01-01

    Neste estudo, faz-se a releitura do injusto penal com base na teoria dos elementos negativos do tipo, analisando o seu acerto e a necessidade de sua aplicação para o desenvolvimento do Direito Penal brasileiro. A teoria dos elementos negativos do tipo surgiu na Alemanha do século XIX, por obra de Adolf Merkel, como forma de buscar a solução para uma lacuna deixada pelo antigo Código Penal alemão sobre o erro relativo aos pressupostos fáticos de uma causa de justificação. Merkel e seus seguido...

  19. TIPOS DE DISCURSO

    OpenAIRE

    Garcia, Afrânio; UERJ

    2012-01-01

    O professor Adilson Citelli, em seu excelente livro Linguageme persuasão, apresenta cinco tipos de discurso:§ discurso dominante§ discurso autorizado§ discurso polêmico,§ discurso lúdico§ discurso autoritário.

  20. Simplified system for the pressure control of a Nucleo electric central of the BWR type; Sistema simplificado para el control de presion de una central Nucleoelectrica del tipo BWR

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez J, J. [FI-UNAM, DEPFI Campus Morelos, Jiutepec, Morelos (Mexico)

    2003-07-01

    One of the main preoccupations of the electric power generator stations is the appropriate operation of the same ones. The operators must be qualified to respond in an adequate way and to be able to take to these power stations to an optimal, sure and stable operation condition under any circumstance. The Laboratory of Analysis in Nuclear Reactors Engineering (LAIRN) of the Engineering Faculty of UNAM (Fl) in collaboration with the International Atomic Energy Agency (IAEA), it develops an interactive classroom simulator in which simulations of the phenomena which take place in a nuclear power station are executed. The classroom simulator bases its operation on specialized nuclear codes feeding interactive graphic unfolding with those that it is possible to make a monitoring, supervision and control of the behavior of the power station under any operation regime, either in normal operation, transitory events or postulated accident sequence. The development of this classroom simulator includes a modular and re configurable structure. Due to it is indispensable to count with a higher inter activity with the system it is included the simulation of the control system of the plant and inside the same, one of those more important it is the reactor pressure control system. The present work describes the conceptual design and the used methodology for the development and implementation in the simulator of a simplified model of the pressure control system for a BWR generic central. The reach of the development will allow to accomplish the necessary tests to demonstrate that this has an adequate performance according to the carried out simplifications. (Author)

  1. O Herpesvírus bovino tipo 5 (BoHV-5) pode utilizar as rotas olfatória ou trigeminal para invadir o sistema nervoso central de coelhos, dependendo da via de inoculação

    OpenAIRE

    Diel,Diego Gustavo; Fonseca,Erika Toledo da; Souza,Soraia Figueiredo de; Mazzanti,Alexandre; Bauermann,Fernando; Weiblen,Rudi; Flores, Eduardo Furtado

    2005-01-01

    O herpesvírus bovino tipo 5 (BoHV-5) é um agente importante de meningoencefalite em bovinos. Após replicação na mucosa nasal, acredita-se que o vírus invada o cérebro principalmente pela via olfatória. Para investigar a importância dessa via na patogenia da infecção neurológica em um modelo animal, coelhos recém-desmamados (30 dias) foram submetidos à ablação cirúrgica dos bulbos olfatórios (BOs) e posteriormente inoculados pela via intranasal (IN) ou no saco conjuntival (IC) com uma cepa alt...

  2. Ataxia espinocerebelar tipo 6: relato de caso

    Directory of Open Access Journals (Sweden)

    Bianca Simone Zeigelboim

    2014-10-01

    Full Text Available O objetivo deste estudo foi verificar as alterações vestibulococleares observadas em um caso de ataxia espinocerebelar tipo 6. O caso foi encaminhado do Hospital de Clínicas para o Laboratório de Otoneurologia de uma Instituição de Ensino e foi submetido aos seguintes procedimentos: anamnese, inspeção otológica, avaliações audiológica e vestibular. O caso retrata uma paciente com diagnóstico genético de ataxia espinocerebelar tipo 6, do sexo feminino, com 57 anos de idade, que referiu desequilíbrio à marcha com tendência a queda para a esquerda, disartria e disfonia. Na avaliação audiológica apresentou configuração audiométrica descendente a partir da frequência de 4kHz e curva timpanométrica do tipo "A" com presença dos reflexos estapedianos bilateralmente. No exame vestibular observou-se na pesquisa da vertigem posicional presença de nistagmo vertical inferior e oblíquo, espontâneo e semiespontâneo múltiplo com características centrais (ausência de latência, paroxismo, fatigabilidade e vertigem, nistagmooptocinético abolido e hiporreflexia à prova calórica. Constataram-se alterações labirínticas que indicaram afecção do sistema vestibular central evidenciando-se a importância dessa avaliação. A existência da possível relação entre os achados com os sintomas vestibulares apresentados pela paciente apontou a relevância do exame labiríntico neste tipo de ataxia uma vez que a presença do nistagmo vertical inferior demonstrou ser frequente neste tipo de patologia.

  3. Asteroids IV

    Science.gov (United States)

    Michel, Patrick; DeMeo, Francesca E.; Bottke, William F.

    . Asteroids, like planets, are driven by a great variety of both dynamical and physical mechanisms. In fact, images sent back by space missions show a collection of small worlds whose characteristics seem designed to overthrow our preconceived notions. Given their wide range of sizes and surface compositions, it is clear that many formed in very different places and at different times within the solar nebula. These characteristics make them an exciting challenge for researchers who crave complex problems. The return of samples from these bodies may ultimately be needed to provide us with solutions. In the book Asteroids IV, the editors and authors have taken major strides in the long journey toward a much deeper understanding of our fascinating planetary ancestors. This book reviews major advances in 43 chapters that have been written and reviewed by a team of more than 200 international authorities in asteroids. It is aimed to be as comprehensive as possible while also remaining accessible to students and researchers who are interested in learning about these small but nonetheless important worlds. We hope this volume will serve as a leading reference on the topic of asteroids for the decade to come. We are deeply indebted to the many authors and referees for their tremendous efforts in helping us create Asteroids IV. We also thank the members of the Asteroids IV scientific organizing committee for helping us shape the structure and content of the book. The conference associated with the book, "Asteroids Comets Meteors 2014" held June 30-July 4, 2014, in Helsinki, Finland, did an outstanding job of demonstrating how much progress we have made in the field over the last decade. We are extremely grateful to our host Karri Muinonnen and his team. The editors are also grateful to the Asteroids IV production staff, namely Renée Dotson and her colleagues at the Lunar and Planetary Institute, for their efforts, their invaluable assistance, and their enthusiasm; they made life as

  4. Crescimento de genótipos de frangos tipo caipira

    Directory of Open Access Journals (Sweden)

    R. C. Veloso

    2015-10-01

    Full Text Available RESUMOObjetivou-se com este trabalho comparar o padrão de crescimento, mediante ajustes das respectivas curvas de crescimento por modelos não lineares, bem como estudar o desenvolvimento de cortes de carcaça em relação ao peso da carcaça em diferentes genótipos de frangos tipo caipira. Foram utilizados 840 pintos de um dia, machos, distribuídos em delineamento inteiramente ao acaso, dos seguintes genótipos da linhagem Redbro: Caboclo, Carijó, Colorpak, Gigante Negro, Pesadão Vermelho, Pescoço Pelado e Tricolor. As aves foram alojadas em 28 boxes, sendo 30 aves/boxe, em galpão de alvenaria com acesso a um piquete de 45m², com quatro repetições. O peso corporal individual dos frangos foi medido ao nascer, aos 14, 28, 42, 56, 70 e 84 dias de idade. Para a determinação das curvas de crescimento do peso corporal das aves, os dados coletados foram avaliados por meio dos modelos não lineares: Brody, Gompertz, Logístico, Richards e von Bertalanffy. Foi empregado o PROC NLIN do SAS, utilizando-se o método interativo de Gauss-Newton. Os critérios usados para escolha do modelo de melhor ajuste da curva de crescimento foram o coeficiente de determinação, o desvio padrão assintótico, o desvio médio absoluto dos resíduos e o índice assintótico. As análises para obtenção dos coeficientes alométricos foram realizadas por meio do PROC GLM do SAS para os genótipos Carijó, Colorpak, Pesadão Vermelho, Pescoço Pelado e Tricolor. Foram avaliados os pesos da carcaça, do peito, das coxas, das sobrecoxas, das pernas e das asas das aves abatidas aos 85 dias de idade. Apenas as equações propostas por Gompertz, von Bertalanffy e Logístico atingiram a convergência, e o modelo proposto por von Bertalanffy foi o mais adequado para descrever o crescimento dos genótipos de frangos caipiras. Todos os cortes avaliados apresentaram crescimento tardio em relação ao peso da carcaça em genótipos de frangos tipo caipira.

  5. Aplicación de la teoría de perturbación método diferencial al estudio de sensibilidad en generadores de vapor de centrales nucleares tipo PWR

    OpenAIRE

    Giol, Roberto

    1989-01-01

    En este trabajo se presenta una ampliación del formalismo diferencial de la teoría de perturbación a un modelo homogéneo de simulación del comportamiento estacionario de generadores de vapor de centrales nucleares PWR. El programa PERGEVAP, desarrollado a partir del modelo del código GEVAP de Souza, permite realizar cálculos de la sensibilidad de funciones lineales (como la temperatura media del primario) y no-lineales (como el flujo de calor medio) a variaciones en los parámetros termohidráu...

  6. en diferentes tipos de matrimonio

    Directory of Open Access Journals (Sweden)

    Mirta Margarita Flores Galaz

    2005-01-01

    Full Text Available En el presente estudio se analizan los estilos de poder y los estilos de negociación del conflicto utilizados por parejas yucatecas, así como la relación entre cada uno de los factores de los estilos de poder y de negociación por tipo de matrimonio, de acuerdo a los ingresos individuales de las esposas y en nivel de trabajo.

  7. "CEZAC 06": nueva variedad de ajo tipo Jaspeado para la región norte centro de México "CEZAC 06": new Jaspeado garlic cultivar for the northem-central region of Mexico

    Directory of Open Access Journals (Sweden)

    Manuel Reveles-Hernández

    2011-08-01

    Full Text Available Alrededor de 5 200 hectáreas de ajo son cultivadas en México donde la región norte centro, es una de las principales áreas productoras de esta hortaliza. La falta de variedades de ajo localmente adaptadas es una seria desventaja para los productores de ajo. En este reporte se mencionan las principales características agronómicas de "CEZAC 06", una nueva variedad de ajo disponible para los productores de los estados de Zacatecas, Aguascalientes, Durango, Chihuahua y Coahuila. Las principales ventajas de esta variedad son rendimientos más altos, bulbos consistentemente redondos, menor número de dientes por bulbo y maduración homogénea. En parcelas comerciales el rendimiento se ha mejorado en 9-17% y se han alcanzado rendimientos de hasta 30 t ha-1 con el uso de "CEZAC 06".About 5 200 hectares of garlic are cultivated in Mexico; the north-central region is one of the main producing areas of this vegetable. The lack of locally adapted varieties of garlic is a serious disadvantage for garlic producers. In this paper are mentioned the main agronomic characteristics of "CEZAC 06", a new garlic variety available for producers of Zacatecas, Aguascalientes, Durango, Chihuahua and Coahuila. The main advantages of this variety are higher yield, consistently round bulbs, fewer numbers of cloves per bulb and homogeneous maturation. In commercial plots, yield has improved in 9-17% and there have been achieved yields of up to 30 t ha-1 using "CEZAC 06".

  8. O Herpesvírus bovino tipo 5 (BoHV-5) pode utilizar as rotas olfatória ou trigeminal para invadir o sistema nervoso central de coelhos, dependendo da via de inoculação Bovine herpesvirus 5 may use the olfactory and trigeminal pathways to invade the central nervous system of rabbits, depending upon the route of inoculation

    OpenAIRE

    Diego Gustavo Diel; Erika Toledo da Fonseca; Soraia Figueiredo de Souza; Alexandre Mazzanti; Fernando Bauermann; Rudi Weiblen; Eduardo Furtado Flores

    2005-01-01

    O herpesvírus bovino tipo 5 (BoHV-5) é um agente importante de meningoencefalite em bovinos. Após replicação na mucosa nasal, acredita-se que o vírus invada o cérebro principalmente pela via olfatória. Para investigar a importância dessa via na patogenia da infecção neurológica em um modelo animal, coelhos recém-desmamados (30 dias) foram submetidos à ablação cirúrgica dos bulbos olfatórios (BOs) e posteriormente inoculados pela via intranasal (IN) ou no saco conjuntival (IC) com uma cepa alt...

  9. Un problema tipo bin-packing

    Directory of Open Access Journals (Sweden)

    Geovanni Figueroa Mata

    2011-09-01

    Full Text Available Se presentan dos algoritmos heurísticos para resolver un problema de tipo binpacking en el cual se quiere guardar objetos de n tipos diferentes (en donde la demanda del objeto de tipo i-ésimo está dada por d1 en m tipos de recipientes con capacidades no necesariamente iguales; todos los recipientes de tipo j =1,2,...,m deben tener la misma distribución de los objetos. El objetivo es minimizar el costo de los recipientes por utilizar, donde el costo de cada tipo de recipiente está dado por wj (j =1,2,...,m. Para cada recipiente de tipo j =1,2,...,m se deben encontrar el número de repeticiones xj del recipiente, así como el número de copias aij del objeto i-ésimo que se deben almacenar en el recipiente j-ésimo (j =1,2,...,m.

  10. INSULINA Y ENFERMEDAD DE ALZHEIMER: UNA DIABETES TIPO 3?

    Directory of Open Access Journals (Sweden)

    Andrés Jagua Gualdrón

    2007-03-01

    Full Text Available La enfermedad de Alzheimer es un trastorno degenerativo del sistema nervioso central cuya incidencia probablemente aumentará en los próximos años. Los resultados de investigaciones recientes relacionan esta enfermedad con trastornos en la señal de la insulina a nivel de las neuronas. ¿Es la Enfermedad de Alzheimer una diabetes tipo 3? En este documento presentamos una reseña breve de las evidencias que se levantan en torno a este modelo de la enfermedad.

  11. NNDSS - Table IV. Tuberculosis

    Data.gov (United States)

    U.S. Department of Health & Human Services — NNDSS - Table IV. Tuberculosis - 2014.This Table includes total number of cases reported in the United States, by region and by states, in accordance with the...

  12. NNDSS - Table IV. Tuberculosis

    Data.gov (United States)

    U.S. Department of Health & Human Services — NNDSS - Table IV. Tuberculosis - 2015.This Table includes total number of cases reported in the United States, by region and by states, in accordance with the...

  13. NNDSS - Table IV. Tuberculosis

    Data.gov (United States)

    U.S. Department of Health & Human Services — NNDSS - Table IV. Tuberculosis - 2016.This Table includes total number of cases reported in the United States, by region and by states, in accordance with the...

  14. Interplanetary Type IV Bursts

    CERN Document Server

    Hillaris, Alexander; Nindos, Alexander

    2016-01-01

    In this work we study the characteristics of moving type IV radio bursts which extend to the hectometric wavelengths (interplanetary type IV or type IV IP bursts) and their relationship with energetic phenomena on the Sun. Our dataset comprised 48 Interplanetary type IV bursts observed by the Wind/WAVES in the 13.825 MHz?20 KHz frequency range. The dynamic spec tra of the RSTN, DAM, ARTEMIS-IV, CULGOORA, Hiraiso and IZMIRAN Radio-spectrographs were used to track the evolution of the events in the low corona; these were supplemented with SXR ?ux recordings from GOES and CME data from LASCO. Positional information for the coronal bursts were obtained by the Nan\\c{c}ay radioheliograph (NRH). We examined the relationship of the type IV events with coronal radio bursts, CMEs and SXR ?ares. The majority of the events (45) were characterized as compact; their duration was on average 106 min. This type of events were, mostly, associated with M and X class ?ares (40 out of 45) and fast CMEs; 32 of these events had CME...

  15. O Herpesvírus bovino tipo 5 (BoHV-5 pode utilizar as rotas olfatória ou trigeminal para invadir o sistema nervoso central de coelhos, dependendo da via de inoculação Bovine herpesvirus 5 may use the olfactory and trigeminal pathways to invade the central nervous system of rabbits, depending upon the route of inoculation

    Directory of Open Access Journals (Sweden)

    Diego Gustavo Diel

    2005-09-01

    Full Text Available O herpesvírus bovino tipo 5 (BoHV-5 é um agente importante de meningoencefalite em bovinos. Após replicação na mucosa nasal, acredita-se que o vírus invada o cérebro principalmente pela via olfatória. Para investigar a importância dessa via na patogenia da infecção neurológica em um modelo animal, coelhos recém-desmamados (30 dias foram submetidos à ablação cirúrgica dos bulbos olfatórios (BOs e posteriormente inoculados pela via intranasal (IN ou no saco conjuntival (IC com uma cepa altamente neurovirulenta do BoHV-5 (SV-507. Após inoculação IN, 10/10 coelhos no Grupo Controle (com BOs desenvolveram enfermidade neurológica, com início dos sinais clínicos entre os dias 5 e 10 pós-inoculação (pi (média de 7,5 dias; em contraste, no grupo submetido à ablação dos BOs (n=11, apenas um animal (9,1% desenvolveu doença neurológica (início no dia 17pi. Administração de dexametasona aos animais sobreviventes (n=10 no dia 50 pi resultou em excreção viral em secreções nasais e/ou oculares por oito destes, demonstrando que o vírus foi capaz de atingir o gânglio trigêmeo (TG durante a infecção aguda. Esses resultados demonstram que a rota olfatória representa a via principal, mas não única, de acesso ao cérebro de coelhos após inoculação IN. Para investigar o papel de uma segunda possível via de acesso, grupos de coelhos controle (n=12 ou submetidos à ablação dos BOs (n=12 foram inoculados no saco conjuntival (IC, após o qual o vírus poderia utilizar o ramo oftálmico do nervo trigêmeo para invadir o cérebro. Dez coelhos controle (83,3 % desenvolveram doença neurológica após inoculação IC, com início dos sinais entre os dias 11 e 20 (média 15,3 dias. A ablação prévia dos BOs não afetou a freqüência ou o curso da doença neurológica nesse grupo: 10/12 coelhos (83,3 % sem os BOs desenvolveram a doença neurológica, com os sinais iniciando entre os dias 9 e 15pi (média 12,7 dias. Esses

  16. Algunos tipos de preferencias no transitivas

    OpenAIRE

    Carmen Vázquez

    2010-01-01

    Este trabajo ofrece una visión sobre la modelación de las relaciones de preferencias del consumidor diferente a la clásica, pues prescindimos de la hipótesis de transitividad. Concretamente, analizamos dos tipos de relaciones de preferencias no transitivas, las acíclicas y las asimétricas, que bajo ciertas condiciones, admiten tipos de representación numérica distintos. Justificamos la aceptación de las mismas mediante ejemplos prácticos y vemos también resultados que garantizan la existencia...

  17. Estrutura temporal dos tipos de xuro

    OpenAIRE

    Reboredo Nogueira, Juan Carlos

    2013-01-01

    Esta unidade didáctica forma parte do curso de Análise Económica dos Mercados Financeiros I que se imparte no primeiro cuadrimestre do Máster en Economía: Organización Industrial e Mercados Financeiros. Esta unidade ten como obxectivo analizar a estrutura temporal dos tipos de xuro, é dicir a relación existente entre os tipos de xuro a diferentes prazos. En particular, estudarase a curva cupón cero, a súa utilidade no proceso de valoración dos activos financeiros e os diferentes mé...

  18. Interplanetary Type IV Bursts

    Science.gov (United States)

    Hillaris, A.; Bouratzis, C.; Nindos, A.

    2016-08-01

    We study the characteristics of moving type IV radio bursts that extend to hectometric wavelengths (interplanetary type IV or type {IV}_{{IP}} bursts) and their relationship with energetic phenomena on the Sun. Our dataset comprises 48 interplanetary type IV bursts observed with the Radio and Plasma Wave Investigation (WAVES) instrument onboard Wind in the 13.825 MHz - 20 kHz frequency range. The dynamic spectra of the Radio Solar Telescope Network (RSTN), the Nançay Decametric Array (DAM), the Appareil de Routine pour le Traitement et l' Enregistrement Magnetique de l' Information Spectral (ARTEMIS-IV), the Culgoora, Hiraso, and the Institute of Terrestrial Magnetism, Ionosphere and Radio Wave Propagation (IZMIRAN) Radio Spectrographs were used to track the evolution of the events in the low corona. These were supplemented with soft X-ray (SXR) flux-measurements from the Geostationary Operational Environmental Satellite (GOES) and coronal mass ejections (CME) data from the Large Angle and Spectroscopic Coronagraph (LASCO) onboard the Solar and Heliospheric Observatory (SOHO). Positional information of the coronal bursts was obtained by the Nançay Radioheliograph (NRH). We examined the relationship of the type IV events with coronal radio bursts, CMEs, and SXR flares. The majority of the events (45) were characterized as compact, their duration was on average 106 minutes. This type of events was, mostly, associated with M- and X-class flares (40 out of 45) and fast CMEs, 32 of these events had CMEs faster than 1000 km s^{-1}. Furthermore, in 43 compact events the CME was possibly subjected to reduced aerodynamic drag as it was propagating in the wake of a previous CME. A minority (three) of long-lived type {IV}_{{IP}} bursts was detected, with durations from 960 minutes to 115 hours. These events are referred to as extended or long duration and appear to replenish their energetic electron content, possibly from electrons escaping from the corresponding coronal

  19. IV access in dental practice.

    LENUS (Irish Health Repository)

    Fitzpatrick, J J

    2009-04-01

    Intravenous (IV) access is a valuable skill for dental practitioners in emergency situations and in IV sedation. However, many people feel some apprehension about performing this procedure. This article explains the basic principles behind IV access, and the relevant anatomy and physiology, as well as giving a step-by-step guide to placing an IV cannula.

  20. Capítulo IV. El Tipo Humano: Hombre de Paiján

    OpenAIRE

    Lacombe, Jean-Paul

    2015-01-01

    Antes de concluir, conviene resumir los principales caracteres anatómicos de los individuos de Paiján. Son individuos de talla más bien elevada, con una fuerte musculatura aunque los huesos sean gráciles; su cráneo es muy alargado, su cara alta, sus órbitas casi circulares y la nariz estrecha. Presentan un prognatismo facial total importante (como los australo-melanesios), diferente del prognatismo facial superior de los melano-africanos. La mandíbula es maciza con inserciones musculares marc...

  1. Chemotherapy versus best supportive care in stage IV non-small cell lung cancer, non metastatic to the brain Quimioterapia versus melhor tratamento de suporte em câncer de pulmão estádio clínico IV não metastático para o sistema nervoso central

    Directory of Open Access Journals (Sweden)

    Agnaldo Anelli

    2001-04-01

    Full Text Available Stage IV non-small cell lung cancer is a fatal disease, with a median survival of 14 months. Systemic chemotherapy is the most common approach. However the impact in overall survival and quality of life still a controversy. OBJECTIVES: To determine differences in overall survival and quality of life among patients with stage IV non-small cell lung cancer non-metastatic to the brain treated with best supportive care versus systemic chemotherapy. PATIENTS: From February 1990 through December 1995, 78 eligible patients were admitted with the diagnosis of stage IV non-small cell lung cancer . Patients were divided in 2 groups: Group A (n=31 -- treated with best supportive care , and Group B (n=47 -- treated with systemic chemotherapy. RESULTS: The median survival time was 23 weeks (range 5 -- 153 weeks in Group A and 55 weeks (range 7.4 -- 213 weeks in Group B (p=0.0018. In both groups, the incidence of admission for IV antibiotics and need of blood transfusions were similar. Patients receiving systemic chemotherapy were also stratified into those receiving mytomycin, vinblastin, and cisplatinum, n=25 and those receiving other combination regimens (platinum derivatives associated with other drugs, n=22. Patients receiving mytomycin, vinblastin, and cisplatinum, n=25 had a higher incidence of febrile neutropenia and had their cycles delayed for longer periods of time than the other group. These patients also had a shorter median survival time (51 versus 66 weeks, p=0.005. CONCLUSION: In patients with stage IV non-small cell lung cancer, non-metastatic to the brain, chemotherapy significantly increases survival compared with best supportive care.O câncer de pulmão de células não pequenas em estádio IV é uma doença fatal, com uma sobrevida mediana de seis meses. Quimioterapia é a abordagem mais freqüente, apresentando um impacto na sobrevida controverso e questionável alteração na qualidade de vida. OBJETIVOS: Comparar o impacto na

  2. Marketing produktu Karel IV.

    OpenAIRE

    Mikšů, Šárka

    2009-01-01

    Goal of the thesis Marketing of the product Karel IV. is to propose chanels of marketing communication and indicate possibilities of next product's development. Theoretical part is based on marketing plan and it's partition. In the practical part you can find market analysis and competing products analysis, product's evolution description and marketing research.

  3. Dibromidodimethyldipyridineplatinum(IV

    Directory of Open Access Journals (Sweden)

    Mairéad E. Kelly

    2008-11-01

    Full Text Available In the title complex, [PtBr2(CH32(C5H5N2], the PtIV metal centre lies on a twofold rotation axis and adopts a slightly distorted octahedral coordination geometry. The structure displays weak intramolecular C—H...Br hydrogen-bonding interactions.

  4. PLATO IV Accountancy Index.

    Science.gov (United States)

    Pondy, Dorothy, Comp.

    The catalog was compiled to assist instructors in planning community college and university curricula using the 48 computer-assisted accountancy lessons available on PLATO IV (Programmed Logic for Automatic Teaching Operation) for first semester accounting courses. It contains information on lesson access, lists of acceptable abbreviations for…

  5. Gaseous equilibrium in sector CP IV of the Cerro Prieto, B.C. Mexico geothermal field; Equilibrio gaseoso en el sector CP IV del campo geotermico Cerro Prieto, B.C., Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Barragan Reyes, Rosa Maria; Arellano Gomez, Victor Manuel; Portugal Marin, Enrique [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico); De Leon Vivar, Jesus [Comision Federal de Electricidad, Campo Geotermico Cerro Prieto, Cerro Prieto, B. C. (Mexico)

    2007-07-01

    Sector CP IV is located in the NE portion of the Cerrro Prieto geothermal field. The wells of this zone produce two-phase fluids, with different characteristics as far as their steam fraction content; in the central part and towards the NW the fluids are of dominant liquid type whereas towards the E and the S, the fluid contains a relatively higher steam fraction. The results of gaseous equilibrium FT- HSH3 showed that the fluids in the deposit are at temperatures between 275 Celsius degrees and 310 Celsius degrees and contain steam fractions between 0.01 and 0.5. The data found for the natural state are aligned in a tendency defined in the diagram FT- HSH3, that suggest the wells receive different proportions from preexisting steam in the deposit, which are mixed with the liquid phase to produce the observed discharges. The present data, besides showing the presence of deposit steam, also indicates the entrance of lower temperature fluid in the central part of sector CP IV. [Spanish] El sector CP IV se localiza en la porcion NE del campo geotermico Cerro Prieto. Los pozos de esta zona producen fluidos bifasicos, con diferentes caracteristicas en cuanto a su contenido de fraccion de vapor: en la parte central y hacia el NW los fluidos son de tipo liquido dominante mientras que hacia el E y hacia el S, el fluido contiene una fraccion relativamente alta de vapor. Los resultados de equilibrio gaseoso FT-HSH3 mostraron que los fluidos en el yacimiento se encuentran a temperaturas de entre 275 grados Celsius y 310 grados Celsius y contienen fracciones de vapor de entre -.01 y .5. Los datos hallados para el estado natural se alinean en una tendencia definida en el diagrama FT-HSH3, que sugiere que los pozos reciben diferentes proporciones de vapor pre-existente en el yacimiento, que se mezclan con fase liquida para producir las descargas que se observan. Los datos actuales, ademas de mostrar la presencia de vapor de yacimiento, tambien indican la entrada de fluidos de

  6. Neodesarrollismo y el tipo de cambio competitivo

    Directory of Open Access Journals (Sweden)

    Alejandro Fiorito

    2015-01-01

    Full Text Available En este trabajo se intenta mostrar que las modificaciones en los tipos de cambio tienen efectos limitados en el aumento del producto, mientras que, inversamente, esos cambios impactan especialmente en la distribución del ingreso al incidir en los precios domésticos. Se analizan y muestran múltiples referencias de la literatura internacional que cuestionan este "consenso de tipos de cambio competitivos". Se realizan correlaciones que muestran resultados distintos de los obtenidos en Rodrik (2008 con los mismos datos utilizados, aunque simplemente cambiando la metodología de datos de panel y usando en cambio una más convencional de series de tiempo.

  7. Tipos e mitos do pensamento brasileiro

    Directory of Open Access Journals (Sweden)

    Ianni Octavio

    2002-01-01

    Full Text Available No pensamento brasileiro são freqüentes os "tipos ideais" elaborados por diferentes autores e que se tornam emblemáticos, notáveis ou mesmo definitivos, podendo, às vezes, figurar como mitos. Esse é o caso do bandeirante, do gaúcho, do Jeca Tatu, do Macunaíma, do homem cordial e outros. Vale a pena refletir sobre este aspecto da cultura e do pensamento brasileiros.

  8. Eficacia de la Galantamina en los síntomas de demencia del tipo Alzheimer, vascular y mixta

    OpenAIRE

    José Luis Acosta-Patiño; Joaquín Jiménez-Alayola; Lucas López-Segovia; Manuel E. Borbolla-Sala

    2006-01-01

    Objetivo: evaluar la eficacia de la galantamina sobre los síntomas de demencia tipo Alzheimer, vascular o mixta en pacientes ambulatorios. Material y métodos: estudio experimental Fase IV en donde se incluyeron 32 pacientes con diagnóstico de demencia con base en el DSM-IV, se les administró solución gotas de galantamina con incremento gradual de la dosis, durante tres meses: 8, 16 y 24 mg/día, evaluando cada mes; tolerabilidad, eventos adversos, se aplicó y evaluó el minimental de Folstein. ...

  9. Enhanced Design Alternative IV

    Energy Technology Data Exchange (ETDEWEB)

    N. E. Kramer

    1999-05-18

    This report evaluates Enhanced Design Alternative (EDA) IV as part of the second phase of the License Application Design Selection (LADS) effort. The EDA IV concept was compared to the VA reference design using criteria from the ''Design Input Request for LADS Phase II EDA Evaluations'' (CRWMS M&O 1999b) and (CRWMS M&O 1999f). Briefly, the EDA IV concept arranges the waste packages close together in an emplacement configuration known as ''line load''. Continuous pre-closure ventilation keeps the waste packages from exceeding the 350 C cladding and 200 C (4.3.13) drift wall temperature limits. This EDA concept keeps relatively high, uniform emplacement drift temperatures (post-closure) to drive water away from the repository and thus dry out the pillars between emplacement drifts. The waste package is shielded to permit human access to emplacement drifts and includes an integral filler inside the package to reduce the amount of water that can contact the waste form. Closure of the repository is desired 50 years after first waste is emplaced. Both backfill and a drip shields will be emplaced at closure to improve post-closure performance.

  10. Identificação e diferenciação de herpesvírus bovino tipos 1 e 5 isolados de amostras clínicas no Centro-Sul do Brasil, Argentina e Uruguai (1987-2006 Identification and differentiation of herpesvirus types 1 and 5 isolated from clinical samples in central-southern Brazil, Argentina and Uruguay (1987-2006

    Directory of Open Access Journals (Sweden)

    Mariana Sá e Silva

    2007-10-01

    Full Text Available Os herpesvírus bovino tipos 1 e 5 (BoHV-1; BoHV-5 são genética e antigenicamente muito semelhantes e por isso são indistinguíveis pela maioria dos testes diagnósticos. Como o BoHV-1 tem sido classicamente associado com doença respiratória e genital, os herpesvírus isolados dessas enfermidades têm sido provisoriamente - e às vezes definitivamente - identificados como BoHV-1. Da mesma forma, os casos de infecção neurológica por herpesvírus em bovinos têm sido atribuídos em sua totalidade ao BoHV-5. Este trabalho relata a identificação de 40 amostras de herpesvírus isoladas de diferentes casos clínicos na região Centro-Sul do Brasil, Argentina e Uruguai entre 1987 e 2006, pelo uso de um PCR capaz de diferenciar esses vírus. As amostras identificadas como BoHV-1 (n=16 foram isoladas de doença respiratória (n=3, balanopostite e/ou vulvovaginite (n=3, do sêmen de touros saudáveis (n=5 e de casos doença neurológica (n=5. As amostras virais identificadas como BoHV-5 (n=24 foram em sua maioria isoladas de doença neurológica (n=21, mas também do sêmen de touros saudáveis (n=2 e do baço de um bezerro com doença sistêmica (n=1. Esses resultados demonstram que tanto o BoHV-1 como o BoHV-5 não estão estritamente associados às suas respectivas síndromes clínicas e que podem estar freqüentemente envolvidos em casos clínicos classicamente atribuídos ao outro vírus. Esses achados também reforçam a necessidade de se identificar corretamente os isolados de herpesvírus para um melhor conhecimento da sua patogenia e epidemiologia.Bovine herpesviruses types 1 and 5 (BoHV-1; BoHV-5 are genetically and antigenically closely related such they can not be distinguished by routine diagnostic tests. As BoHV-1 has been historically associated with respiratory and genital disease, herpesviruses isolated from these clinical syndromes have been tentatively - and sometimes definitively - diagnosed as BoHV-1. Likewise, cases of

  11. Prevalência, fatores de risco e genótipos da hepatite C entre usuários de drogas Prevalencia, factores de riesgo y genotipos de la hepatitis C entre usuarios de drogas Prevalence, risk factors and genotypes of hepatitis C virus infection among drug users, Central-Western Brazil

    Directory of Open Access Journals (Sweden)

    Carmen L R Lopes

    2009-08-01

    Full Text Available OBJETIVO: Estimar a prevalência e fatores associados à infecção pelo vírus da hepatite C em usuários de drogas e identificar os genótipos e subtipos virais circulantes. MÉTODOS: Estudo realizado com 691 usuários de drogas de 26 centros de tratamento de uso de drogas filantrópicos, particulares e públicos de Goiânia (GO e Campo Grande (MS, entre 2005 e 2006. Dados sociodemográficos e fatores de risco para infecção pelo HCV foram obtidos por meio de entrevistas. Amostras sangüíneas foram testadas para a detecção de anticorpos para o HCV. As amostras positivas foram submetidas à detecção do RNA-HCV pela reação em cadeia da polimerase com iniciadores complementares às regiões 5' NC e NS5B do genoma viral e genotipadas pelo line probe assay (LiPA e por seqüenciamento direto, seguido de análise filogenética. Prevalência e odds ratio foram calculados com intervalo de 95% de confiança. Os fatores de risco com pOBJETIVO: Estimar la prevalencia y factores asociados a la infección por el virus de la hepatitis C en usuarios de drogas e identificar los genotipos y subtipos virales circulantes. MÉTODOS: Estudio realizado con 691 usuarios de drogas de 26 centros de tratamiento de uso de drogas filantrópicos, particulares y públicos de Goiania y Campo Grande (Centro-Oeste, entre 2005 y 2006. Datos sociodemográficos y factores de riesgo para infección por el HCV fueron obtenidos por medio de entrevistas. Muestras sanguíneas fueron evaluadas para la detección de anticuerpos para el HCV. Las muestras positivas fueron sometidas a la detección de RNA-HCV por la reacción en cadena de polimerasa con iniciadores complementarios a las regiones 5' NC y NS5B del genoma viral y genotipadas por el line probe assay (LiPA y por secuenciación directa, seguido del análisis filogenético. Prevalencia y odds ratio fueron calculados con intervalo de 95% de confianza. Los factores de riesgo con pOBJECTIVE: To estimate prevalence of

  12. Error de tipo y el conocimiento del hecho

    OpenAIRE

    Palacios Riquetti, Damián Patricio

    2013-01-01

    Lo que busco es establecer la diferencia entre el error de tipo y el error de prohibición, para luego tratar sobre el conocimiento que debe tener el autor, sobre los elementos del tipo legal, para que se configure un error de tipo, y determinar si el error de tipo es evitable o inevitable, lo que en cada caso llevará a la gradación y a la imposición o no de una pena; trataré sobre el error de los elementos normativos integrados en el tipo penal, comentaré del error sobre el curso causa...

  13. O oraloma da diabetes melitos tipo 1 vs diabetes melitos tipo 2 - um estudo comparativo

    OpenAIRE

    2013-01-01

    A Diabetes Melitos é uma doença de grande prevalência a nível mundial e os seus mecanismos fisiopatológicos não são ainda totalmente conhecidos. Actualmente, a terapêutica seguida em casos de Diabetes Melitos é eminentemente sintomática consistindo na administração de insulina nos casos de Diabetes Melitos tipo 1 ou quando se verifica a falência das células beta do pâncreas de pacientes com Diabetes Melitos tipo 2, ou no controlo da glicemia nos casos de Diabetes Melitos ...

  14. La articulación del espacio doméstico en las casas de patio central. Un estudio para el Noreste peninsular ibérico entre los siglos IV - II a. C.

    Directory of Open Access Journals (Sweden)

    Fernández García, Gloria

    2015-12-01

    Full Text Available In this paper we approach a diachronic comparative study through space syntax analysis methodology of a set of courtyard houses from the East of the Iberian Peninsula dated between the IVth century and the IInd B.C., period previous and immediately to the beginning of Roman domination of these regions. These big complex houses with courtyard have been interpreted as the residences of minority powerful groups, that is to say, local aristocracy. In view of this, we shall try to study the evolution of this social class during this period characterized by economic and politic changes. Domestic space syntax analyses allows us to see the consequences of the adoption of formal changes in houses, for the social relationships. The high syntactic complexity observed in protohistorical houses is the main difference between these and roman houses.Presentamos un estudio comparativo diacrónico a través de la metodología analítica de la sintaxis espacial de un conjunto de casas de patio del este de la Península Ibérica datadas entre el siglo IV y el II a. C., periodo anterior e inmediatamente posterior al inicio de la conquista romana de esta región. Estas grandes casas complejas y con patio han sido interpretadas como las residencias de grupos minoritarios y poderosos: las aristocracias locales. A partir de esta idea trataremos de conocer el comportamiento y evolución de esta clase social durante el periodo de cambio que abordamos. La aplicación de un análisis sintáctico del espacio sobre una serie de casos nos ha permitido conocer las diferentes connotaciones que pueden adquirir las casas con patio. La principal diferencia entre las casas prerromanas e hispanorromanas está marcada por la mayor complejidad sintáctica de las primeras, que procede de las formas de la tradición indígena.

  15. Glaucoma secundario a neurofibromatosis tipo-1

    Directory of Open Access Journals (Sweden)

    Anay Martínez Díaz

    2012-02-01

    Full Text Available Paciente de 59 años de edad, con antecedentes de neurofibromatosis tipo 1 y trauma contuso del ojo derecho desde hace años. Acudió a consulta de oftalmología refiriendo disminución lenta de la visión; al examen físico se constató una agudeza visual de 0.6 en ambos ojos, así como disminución concéntrica del campo visual en la perimetría por confrontación. El examen objetivo mostró en los anexos una pingüécula en ojo derecho y pterigion grado II en ojo izquierdo; en segmento anterior, múltiples nódulos de Lisch en el iris de ambos ojos, y en el ojo derecho, pupila ligeramente midriática, pero reactiva. Se le realizó gonoscopia, oftalmoscopia y perimetría Humphry; en esta última se halló un escotoma arqueado en ojo derecho, y un defecto superior arqueado en el ojo izquierdo. Se concluyó el caso con los diagnósticos de catarata presenil incipiente y glaucoma secundario a neurofibromatosis tipo 1.

  16. What Is New in Rome IV

    Science.gov (United States)

    Schmulson, Max J; Drossman, Douglas A

    2017-01-01

    Functional gastrointestinal disorders (FGIDs) are diagnosed and classified using the Rome criteria; the criteria may change over time as new scientific data emerge. The Rome IV was released in May 2016. The aim is to review the main changes in Rome IV. FGIDs are now called disorders of gut-brain interaction (DGBI). Rome IV has a multicultural rather than a Western-culture focus. There are new chapters including multicultural, age-gender-women’s health, intestinal microenvironment, biopsychosocial, and centrally mediated disorders. New disorders have been included although not truly FGIDs, but fit the new definition of DGBI including opioid-induced gastrointestinal hyperalgesia, opioid-induced constipation, and cannabinoid hyperemesis. Also, new FGIDs based on available evidence including reflux hypersensitivity and centrally mediated abdominal pain syndrome. Using a normative survey to determine the frequency of normal bowel symptoms in the general population changes in the time frame for diagnosis were introduced. For irritable bowel syndrome (IBS) only pain is required and discomfort was eliminated because it is non-specific, having different meanings in different languages. Pain is now related to bowel movements rather than just improving with bowel movements (ie, can get worse with bowel movement). Functional bowel disorders (functional diarrhea, functional constipation, IBS with predominant diarrhea [IBS-D], IBS with predominant constipation [IBS-C], and IBS with mixed bowel habits) are considered to be on a continuum rather than as independent entities. Clinical applications such as diagnostic algorithms and the Multidimensional Clinical Profile have been updated. The new Rome IV iteration is evidence-based, multicultural oriented and with clinical applications. As new evidence become available, future updates are expected. PMID:28274109

  17. Diaquatetrabromidotin(IV trihydrate

    Directory of Open Access Journals (Sweden)

    Fei Ye

    2012-09-01

    Full Text Available The title compound, [SnBr4(H2O2]·3H2O, forms large colourless crystals in originally sealed samples of tin tetrabromide. It constitutes the first structurally characterized hydrate of SnBr4 and is isostructural with the corresponding hydrate of SnCl4. It is composed of SnIV atoms octahedrally coordinated by four Br atoms and two cis-related water molecules. The octahedra exhibit site symmetry 2. They are arranged into columns along [001] via medium–strong O—H...O hydrogen bonds involving the two lattice water molecules (one situated on a twofold rotation axis while the chains are interconnected via longer O—H...Br hydrogen bonds, forming a three-dimensional network.

  18. Phase IV of Drug Development

    OpenAIRE

    Viraj Suvarna

    2010-01-01

    Not all Phase IV studies are post-marketing surveillance (PMS) studies but every PMS study is a phase IV study. Phase IV is also an important phase of drug development. In particular, the real world effectiveness of a drug as evaluated in an observational, non-interventional trial in a naturalistic setting which complements the efficacy data that emanates from a pre-marketing randomized controlled trial (RCT). No matter how many patients are studied pre-marketing in a controlled environment, ...

  19. Confirmatory Factor Analysis of the WAIS-IV/WMS-IV

    Science.gov (United States)

    Holdnack, James A.; Zhou, Xiaobin; Larrabee, Glenn J.; Millis, Scott R.; Salthouse, Timothy A.

    2011-01-01

    The Wechsler Adult Intelligence Scale-fourth edition (WAIS-IV) and the Wechsler Memory Scale-fourth edition (WMS-IV) were co-developed to be used individually or as a combined battery of tests. The independent factor structure of each of the tests has been identified; however, the combined factor structure has yet to be determined. Confirmatory…

  20. Estereótipos e mulheres na cultura marroquina

    OpenAIRE

    Sadiqi,Fatima

    2008-01-01

    Estereótipos sobre as mulheres no Marrocos podem ser caracterizados como crenças culturais incompletas e inexatas mantidas por algumas pessoas e que se encontram inscritos em expressões lingüísticas ou em discursos subliminares. A cultura popular marroquina emprega representações poderosas para transmitir e sustentar tais estereótipos. Embora existam alguns estereótipos positivos, a maioria dos estereótipos sobre as mulheres no Marrocos é negativa e reflete ditames patriarcais subliminares qu...

  1. Ejemplares tipo de Asteraceae (= Compositae de A. L. Cabrera

    Directory of Open Access Journals (Sweden)

    Susana E. Freire

    2000-01-01

    Full Text Available Freire, S. E. & Iharlegui, L. 2000. Ejemplares tipo de Asteraceae (= Compositae de A. L.Cabrera. Darwiniana 38(3-4: 307-364.El presente trabajo representa un catálogo de los ejemplares tipo de 426 especies y 82 variedades deAsteraceae descriptas por A. L. Cabrera entre los años 1931 y 1999. Los taxones se presentan en ordenalfabético. Para cada taxón se indica: diagnosis original, tipo nomenclatural, categoría del tipo, herbario,etiqueta original y nombre actualizado

  2. 铁定千元机 索尼Xperia Tipo/Tipo Dual

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    除了XperiaMiro,还有另外一对因为疯狂点击而早产的双胞胎——XperiaTipo和XperiaTipoDual。两机外观上一摸一样。前者共有白、黑、蓝、红四色可选,后者仅有银、黑两色。Tipoi两兄弟都内置800MHz高通处理器、512MBRAM以及320万像素摄像头,屏幕再度缩减为3.2英寸HVGA级别。具备抗刮划的能力。其中,TipoDual还是一部支持双卡双待的产品.非常符合国内运营商千元机的定制标准。

  3. DSM-IV Progress Report.

    Science.gov (United States)

    Hohenshil, Thomas H.

    1992-01-01

    Notes that Diagnostic and Statistical Manual of Mental Disorders fourth edition (DSM-IV) will become one of most frequently used reference documents in counseling profession. Describes progress being made in development of DSM-IV, scheduled for publication in 1994. Describes revision process and proposed organizational changes and new diagnostic…

  4. Potencial de vida útil pós-colheita de quatro genótipos de melão tipo Galia Potential of postharvest shelf life of four genotypes of Galia type melons

    Directory of Open Access Journals (Sweden)

    Patrícia Lígia Dantas de Morais

    2004-12-01

    Full Text Available Avaliou-se o potencial de vida útil pós-colheita de melões (Cucumis melo L. tipo Galia (genótipos Primal, Solarking, Total e Vicar. Utilizou-se o delineamento inteiramente casualizado em esquema fatorial 4 (genótipos x 4 (tempos de armazenamento: 0, 3, 6 e 9 dias, com três repetições. Os frutos foram colhidos no estádio de maturação IV (predominantemente amarelo e armazenados à temperatura de 20 ± 1ºC e umidade relativa de 50 ± 2%. O genótipo Solarking apresentou uma firmeza média de polpa superior aos demais, do inicio ao final do período de armazenamento. Em todos os genótipos, os valores de sólidos solúveis no início do armazenamento encontraram-se dentro da faixa aceitável para comercialização no mercado externo, havendo pouca variação com o decorrer do período de armazenamento. A aparência interna limitou o tempo de vida útil pós-colheita do genótipo Total em apenas seis dias. Os genótipos Solarking, Vicar e Primal apresentaram maior potencial na conservação pós-colheita, principalmente o híbrido Solarking, que chegou aos nove dias de armazenamento com boa aparência interna.The postharvest life span of Galia (genotypes Primal, Solarking, Total, and Vicar melons (Cucumis melo L. was evaluated by a four (genotypes x four (storage periods: 0, 3, 6, and 9 days factorial experiment, in a completely randomized design with three replications. The fruits were harvested at maturation stage IV (yellow color predominance, and stored under 20 ± 1ºC and HR 50 ± 2%. Solarking's average firmness was better than that of the other genotypes during the experimental period. At the beginning of the experiment all genotypes had soluble solids contents at the level (eight to ten percent required for exportation, with these levels varying slightly during storage. The internal aspect limited to six days the postharvest life span of genotype Total. Solarking, Vicar, and Primal showed great postharvest conservation potential

  5. Miocardiopatía tipo Takotsubo

    Directory of Open Access Journals (Sweden)

    Juan José Ramírez Chaves

    2014-06-01

    Full Text Available La miocardiopatía adquirida de tipo Takotsubo ha sido descrita desde 1991 en pacientes principalmente del género feme­nino, post menopáusicas, quienes posterior a un evento estresante físico o psicológico asocian clínica de dolor precordial, con cambios electrocardiográficos, alteraciones transitorias de contractilidad de predominio anteroapical del ventrículo izquierdo (VI y elevación de los biomarcadores cardiacos, en ausencia de una enfermedad arterial coronaria (EAC aguda como mecanismo desencadenante del cuadro. La fisiopatología no ha sido completamente dilucidada pero existe con­senso sobre la acción tóxica de las catecolaminas sobre el miocardio. El pronóstico es variable y va desde dolor, insuficien­cia cardiaca, choque cardiogénico hasta, la muerte; por lo tanto, constituye un desafío en el diagnóstico diferencial de las causas no ateroescleróticas generadoras de un síndrome coronario agudo (SCA.

  6. Aqueous complexation of thorium(IV), uranium(IV), neptunium(IV), plutonium(III/IV), and cerium(III/IV) with DTPA.

    Science.gov (United States)

    Brown, M Alex; Paulenova, Alena; Gelis, Artem V

    2012-07-16

    Aqueous complexation of Th(IV), U(IV), Np(IV), Pu(III/IV), and Ce(III/IV) with DTPA was studied by potentiometry, absorption spectrophotometry, and cyclic voltammetry at 1 M ionic strength and 25 °C. The stability constants for the 1:1 complex of each trivalent and tetravalent metal were calculated. From the potentiometric data, we report stability constant values for Ce(III)DTPA, Ce(III)HDTPA, and Th(IV)DTPA of log β(101) = 20.01 ± 0.02, log β(111) = 22.0 ± 0.2, and log β(101) = 29.6 ± 1, respectively. From the absorption spectrophotometry data, we report stability constant values for U(IV)DTPA, Np(IV)DTPA, and Pu(IV)DTPA of log β(101) = 31.8 ± 0.1, 32.3 ± 0.1, and 33.67 ± 0.02, respectively. From the cyclic voltammetry data, we report stability constant values for Ce(IV) and Pu(III) of log β(101) = 34.04 ± 0.04 and 20.58 ± 0.04, respectively. The values obtained in this work are compared and discussed with respect to the ionic radius of each cationic metal.

  7. Doença cerebrovascular tipo "moyamoya"

    Directory of Open Access Journals (Sweden)

    Reynaldo A. Brandt

    1976-09-01

    Full Text Available É relatado o caso de um paciente masculino, branco, 34 anos, que apresentou hemorragia meníngea sem sinais de comprometimento cerebral. A carotidoangiografia direita mostrou as alterações típicas do "moyamoya", com estenose da artéria carótida interna ao nível do sifão, acima da origem da artéria comunicante posterior; há uma rede vascular angiomatosa anormal projetando-se na base do cérebro, da qual nascem as artérias cerebrais anterior e média, sendo as artérias comunicante e cerebral posterior hipertrofiadas e de trajeto tortuoso; há anastomoses meningo-corticiais, sendo as artérias meníngeas hipertrofiadas. A carotidoangiografia esquerda mostrou hipertrofia das artérias carótidas comum e interna, com contrastação de ambas as artérias cerebrais anteriores e médias a partir deste lado; a artéria comunicante anterior é do tipo fetal e há a presença anômala da artéria cerebral anterior mediana do corpo caloso. Estes dados apoiam a teoria segundo a qual a doença constitui anomalia do desenvolvimento vascular encefálico, não tendo sido encontrado outro caso na literatura com hipertrofia vicariante da artéria carótida interna contralateral à da lesão típica do "moyamoya".

  8. Fenótipo Rett em paciente com cariótipo XXY: relato de caso

    Directory of Open Access Journals (Sweden)

    SCHWARTZMAN JOSÉ SALOMÃO

    1998-01-01

    Full Text Available Relatamos o caso de um menino com cariótipo XXY que apresenta desordem neurológica progressiva com início por volta dos 11 meses de idade, com estagnação do desenvolvimento seguida de regressão. A criança apresenta, ainda, movimentos estereotipados de mãos, apraxia manual e microcefalia. Investigações não constataram presença de qualquer condição neurológica ou sistêmica definida que pudesse ser apontada como possível etiologia para o quadro descrito. Trata-se de menino com alterações fenotípicas muito similares àquelas consideradas típicas para a síndrome de Rett que, associadas com a alteração cromossômica constatada (cariótipo XXY, constituem quadro de evidente interesse científico.

  9. Genética de la diabetes mellitus tipo 2

    OpenAIRE

    Carmen Carrillo; Arturo Panduro Cerda

    2001-01-01

    Factores genéticos predisponen a la diabetesmellitus (DM) tipo 2 y el desarrollo de la enfermedad depende en gran parte de la alimentación y actividad física (factores ambientales).Existen familias cuyos miembros presentan DMtipo 2 solamente o bien diferentes tipos de diabetes. En general se presenta un patrón de herencia multifactorial, rara vez autosómico dominante o mitocondrial. El riesgo que tienen losfamiliares de pacientes con DM tipo 2 se establece con el valor lambda el cual depende ...

  10. Primeiro caso de botulismo tipo F, em Portugal

    OpenAIRE

    Saraiva, Margarida; Lopes, Teresa Teixeira; Militão, André; Ribeiro, Rosa Santos; Coelho, Adelaide; Moura, Isabel Bastos; Pena, Cláudia; Bonito, Conceição Costa; Cunha, Isabel Campos; Sousa, Isabel; Toscano, Maria Manuel; Gomes, Carlos Orta; Soares, Elsa; Tavares, António; Calhau, Maria Antónia

    2016-01-01

    A nível mundial, estão descritos poucos casos de botulismo tipo F em humanos. Em julho de 2016 foi identificado o primeiro caso de botulismo tipo F, em Portugal. Foi detetada toxina botulínica tipo F (BoNT/F) nas fezes de um doente com quadro clínico típico de botulismo e isolada a estirpe de Clostridium botulinum produtora de BoNT/F. Worldwide few cases of type F botulism are described in humans. In July 2016 the first case of type F botulism in Portugal was identified. ...

  11. Tipos de interés de los productos bancarios

    OpenAIRE

    Gonzalo Aguado, David

    2016-01-01

    EI trabajo analiza los tipos de interes que las entidades financieras establecen en sus productos. Se configura en tres bloques: Operaciones de Activo, Operaciones de Pasivo y Otras Operaciones. Se puede comprobar que tienen dos opciones : Aplicar un tipo de interés fijo, con el que desde el primer momento conocemos la totalidad de lo que vamos a pagar. La otra opción es aplicar un tipo de interés variable, normalmente aplicando el Euribor más una parte fija. Dentro de cada producto bancario,...

  12. Diabetes tipo 2 en niños. Reporte de caso

    OpenAIRE

    Pinto, Miguel; Servicio de Endocrinología, Hospital Nacional Cayetano Heredia. Facultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia Lima.; Seclén, Segundo; Servicio de Endocrinología, Hospital Nacional Cayetano Heredia. Lima.; Cabello, Emilio; Unidad de Endocrinología Pediátrica, Hospital Nacional Cayetano Heredia. Lima.

    2011-01-01

    Se reporta el caso de una niña de 14 años con antecedentes de obesidad, dislipidemia y diabetes que es referida a nuestro servicio por polidipsia, poliuria y sobrepeso. La paciente tenía el antecedente familiar de ambos padres con diagnóstico de diabetes tipo 2. El examen físico mostró obesidad central y acantosis nigricans severa en los pliegues cutáneos. Los análisis de laboratorio mostraron hiperglicemia, hiperinsulinemia y pép...

  13. Distrofia muscular progressiva congênita tipo Fukuyama descrição de um caso

    Directory of Open Access Journals (Sweden)

    José A. Levy

    1987-06-01

    Full Text Available Os autores relatam o primeiro caso de distrofia muscular progressiva congênita tipo Fukuyama descrito no Brasil, comprovado pelos achados clínicos e exames complementares. É dada ênfase à presença de retrações fibrotendinosas precoces e envolvimento do sistema nervoso central, o que constitui a característica fundamental da afecção. A moléstia é muito freqüente no Japão e pouco descrita em outros países. A etiopatogenia ainda não está definida.

  14. Distrofia muscular progressiva congênita tipo Fukuyama descrição de um caso

    OpenAIRE

    José A. Levy; Mary Souza de Carvalho Alegro; Paulo N. B. Salum; Mario W. Brotto; Ângela Levy

    1987-01-01

    Os autores relatam o primeiro caso de distrofia muscular progressiva congênita tipo Fukuyama descrito no Brasil, comprovado pelos achados clínicos e exames complementares. É dada ênfase à presença de retrações fibrotendinosas precoces e envolvimento do sistema nervoso central, o que constitui a característica fundamental da afecção. A moléstia é muito freqüente no Japão e pouco descrita em outros países. A etiopatogenia ainda não está definida.

  15. Nuevo tipo de apoyos y articulaciones

    Directory of Open Access Journals (Sweden)

    Andrä, Fritz Leonhardt

    1963-11-01

    of theoretical and technical difficulties inherent in these bearings: they also express acknowledgement to German individuals and institutions, for their contribution to this investigation.Las tendencias actuales son funciones que dependen directamente de la presencia creciente y mejorada de los materiales de construcción que se ofrecen al comercio. En el campo de los materiales cabe una marcada subdivisión en naturales y preparados o sintéticos; estos últimos constituyen la preocupación de los autores para su aprovechamiento y adecuada aplicación. De entre ellos, las resinas sintéticas o caucho artificial, dentro de las distintas especies de la extensa familia han gozado de un lugar preferente en este estudio de nuevos tipos de apoyos que presentan los notables ingenieros alemanes Wolfhart Andrä y Fritz Leonhardt. En los ensayos de laboratorio y a escala natural, las variedades comerciales de estas resinas, conocidas con los nombres de «neopreno» y «Teflon», han sido elegidas por presentar, por lo menos actualmente, características marcadamente apropiadas a la finalidad perseguida en este estudio, del que se confía ulterior desarrollo y mejor acogida, por las importantes aplicaciones que de él se derivan en el campo de la ingeniería y construcción. Los autores estudian con detenimiento y sobrado rigor para las aplicaciones prácticas las deformaciones que de estos materiales se espera al someterlos a fuerzas de gran concentración. En los apoyos juega particular interés la distribución de la carga siempre concentrada en superficies relativamente pequeñas, lo que exige elevadas cargas unitarias y, con ello, la utilización de materiales extremadamente nobles para resistirlas con la resistencia que las deformaciones instantáneas requieren para recobrar rápidamente la posición de estabilidad perdida momentáneamente. La fatiga en el ciclo de deformaciones relaja los materiales, y ha de tenerse presente al considerar las características que los

  16. Digital implementation, simulation and tests in MATLAB of the models of Steam line, the turbines, the pressure regulator of a BWR type nucleo electric power plant; Implementacion digital, simulacion y pruebas en MATLAB de los modelos de la linea de vapor, las turbinas y el regulador de presion de una central Nucleoelectrica tipo BWR

    Energy Technology Data Exchange (ETDEWEB)

    Lopez R, A. [UNAM, Laboratorio de Analisis de Ingenieria de Reactores Nucleares, DEPFI, Campus Morelos, en IMTA Jiutepec, Morelos (Mexico)]. e-mail: andyskamx@yahoo.com.mx

    2004-07-01

    In this phase of the project they were carried out exhaustive tests to the models of the steam lines, turbines and pressure regulator of a BWR type nucleo electric central for to verify that their tendencies and behaviors are it more real possible. For it, it was necessary to also analyze the transfer functions of the different components along the steam line until the power generator. Such models define alone the dominant poles of the system, what is not limitation to reproduce a wide range of anticipated transitoriness of a power station operation. In the same manner, it was integrated and proved the integrated model form with the models of feeding water of the SUN-RAH, simulating the nuclear reactor starting from predetermined entrances of the prospective values of the vessel. Also it was coupled with the graphic interface developed with the libraries DirectX implementing a specific monitoring panel for this system. (Author)

  17. Tipo de alimentación en pacientes con diabetes mellitus tipo 2: una muestra de Monterrey (México)

    OpenAIRE

    Samaniego Garay, Rafael Armando; Universidad Autónoma de Zacatecas; Álvarez Bermúdez, Javier; Universidad Autónoma de Nuevo León

    2013-01-01

    El presente trabajo tuvo el propósito de realizar un análisis descriptivo de la frecuencia y tipo de alimentos que se consumen en un grupo de personas con este padecimiento. Se describen los resultados obtenidos en 94 pacientes con diabetes tipo 2 que asistían a un hospital universitario, encontrándose que el tipo de dieta que realizan no es la apropiada, que este recurso es menos utilizado que otras actividades de tratamiento para el control de la diabetes y que el nivel de glucemia en ayuna...

  18. Parâmetros de desempenho e carcaça de genótipos de frangos tipo caipira

    OpenAIRE

    Veloso,R.C.; PIRES, A. V.; R.A. Torres Filho; Pinheiro,S.R.F.; Winkelstroter,L.K.; Alcântara,D.C.; Cruz,C.C.D.C.S.

    2014-01-01

    Objetivou-se com este trabalho avaliar as características de desempenho e de carcaça de sete genótipos de frangos tipo caipira da linhagem Redbro. Foram utilizados 840 pintos de um dia, machos, distribuídos em delineamento inteiramente ao acaso, dos seguintes genótipos: Caboclo, Carijó, Colorpak, Gigante Negro, Pesadão Vermelho, Pescoço Pelado e Tricolor. Os frangos foram alojados em 28 boxes, sendo 30 frangos por boxe, em galpão de alvenaria com a...

  19. Algunos swaps de tipos de interés

    OpenAIRE

    Fernández, Pablo

    2013-01-01

    Empresa A firmó, el 27 de febrero de 2008, un contrato de crédito de 800.000 euros por el que pagaría a Banco B el tipo euríbor más un 1% anual (véase la Figura 1 del caso). La empresa A invertía en plantas de energía solar fotovoltaica. Con este crédito, Empresa A tiene lo que se denomina "riesgo de tipo de interés", que es incertidumbre en el tipo de interés que pagará. El tipo de interés a pagar será alto (grande) si el euríbor sube, y bajo (pequeño) si el euríbor desciende.

  20. Changes in reactivity and in the margins to thermal limits by the inclusion of control rods of advanced type in the Laguna Verde Power plant; Cambios en la reactividad y en los margenes a limites termicos por la inclusion de barras de control de tipo avanzado en la Central Laguna Verde

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez, J.L.; Perusquia, R.; Montes, J.L.; Ortiz, J.J.; Ramirez, J.R. [ININ, Depto. de Sistemas Nucleares, A.P. 18-1027, 11801 Mexico D.F. (Mexico)]. E-mail: jlhm@nuclear.inin.mx

    2004-07-01

    The obtained results are presented when simulating with CM-PRESTO code the cycle 10 of the unit 1 of the Laguna Verde Central, using two advanced types of control bars, besides the originally loaded ones. The two advanced types, to those that are denominated 1AV and 2AV in this work, are of different design, however both have in some place of the bar, a section with hafnium like neutron absorber material. They thought about three different scenarios, in the first one, used as reference, is simulated the cycle 10 using the original control bars, while in the other two cases the advanced types are used. The values of the reactivity were compared and of some margins to the thermal limits obtained when using the bars of advanced type, with those obtained in the case in that alone they are considered those original bars. It was found that in condition of power both advanced types present bigger absorber power of neutrons that the original bars, being quantified in average this bigger power in 0.22 pcm/notch for the type 1AV and in 0.51 pcm/notch for the type 2AV. The affectation of the margins to the observed thermal limits is minimum. (Author)

  1. Confirmatory factor analysis of the WAIS-IV/WMS-IV.

    Science.gov (United States)

    Holdnack, James A; Xiaobin Zhou; Larrabee, Glenn J; Millis, Scott R; Salthouse, Timothy A

    2011-06-01

    The Wechsler Adult Intelligence Scale-fourth edition (WAIS-IV) and the Wechsler Memory Scale-fourth edition (WMS-IV) were co-developed to be used individually or as a combined battery of tests. The independent factor structure of each of the tests has been identified; however, the combined factor structure has yet to be determined. Confirmatory factor analysis was applied to the WAIS-IV/WMS-IV Adult battery (i.e., age 16-69 years) co-norming sample (n = 900) to test 13 measurement models. The results indicated that two models fit the data equally well. One model is a seven-factor solution without a hierarchical general ability factor: Verbal Comprehension, Perceptual Reasoning, Processing Speed, Auditory Working Memory, Visual Working Memory, Auditory Memory, and Visual Memory. The second model is a five-factor model composed of Verbal Comprehension, Perceptual Reasoning, Processing Speed, Working Memory, and Memory with a hierarchical general ability factor. Interpretative implications for each model are discussed.

  2. Contribution of alpha3(IV)alpha4(IV)alpha5(IV) Collagen IV to the Mechanical Properties of the Glomerular Basement Membrane

    Science.gov (United States)

    Gyoneva, Lazarina

    The glomerular basement membrane (GBM) is a vital part of the blood-urine filtration barrier in the kidneys. In healthy GBMs, the main tension-resisting component is alpha3(IV)alpha4(IV)alpha5(IV) type IV collagen, but in some diseases it is replaced by other collagen IV isoforms. As a result, the GBM becomes leaky and disorganized, ultimately resulting in kidney failure. Our goal is to understanding the biomechanical aspects of the alpha3(IV)alpha4(IV)alpha5(IV) chains and how their absence could be responsible for (1) the initial injury to the GBM and (2) progression to kidney failure. A combination of experiments and computational models were designed for that purpose. A model basement membrane was used to compare experimentally the distensibility of tissues with the alpha3(IV)alpha4(IV)alpha5(IV) chains present and missing. The experiments showed basement membranes containing alpha3(IV)alpha4(IV)alpha5(IV) chains were less distensible. It has been postulated that the higher level of lateral cross-linking (supercoiling) in the alpha3(IV)alpha4(IV)alpha5(IV) networks contributes additional strength/stability to basement membranes. In a computational model of supercoiled networks, we found that supercoiling greatly increased the stiffness of collagen IV networks but only minimally decreased the permeability, which is well suited for the needs of the GBM. It is also known that the alpha3(IV)alpha4(IV)alpha5(IV) networks are more protected from enzymatic degradation, and we explored their significance in GBM remodeling. Our simulations showed that the more protected network was needed to prevent the system from entering a dangerous feedback cycle due to autoregulation mechanisms in the kidneys. Overall, the work adds to the evidence of biomechanical differences between the alpha3(IV)alpha4(IV)alpha5(IV) networks and other collagen IV networks, points to supercoiling as the main source of biomechanical differences, discusses the suitability of alpha3(IV)alpha4(IV

  3. Free-format RPG IV

    CERN Document Server

    Martin, Jim

    2013-01-01

    This how-to guide offers a concise and thorough introduction to the increased productivity, better readability, and easier program maintenance that comes with the free-format style of programming in RPG IV. Although free-format information is available in IBM manuals, it is not separated from everything else, thereby requiring hours of tedious research to track down the information needed. This book provides everything one needs to know to write RPG IV in the free-format style, and author Jim Martin not only teaches rules and syntax but also explains how this new style of coding has the pot

  4. Manifestações radiológicas da mucopolissacaridose tipo VI

    Directory of Open Access Journals (Sweden)

    Turtelli Celso Montenegro

    2002-01-01

    Full Text Available O autor relata as alterações radiológicas da mucopolissacaridose tipo VI (mucopolissacárides VI observadas em dois irmãos. Foram realizadas radiografias convencionais do esqueleto e estudo por ressonância magnética do sistema nervoso central. As alterações osteoarticulares são bem conhecidas e em geral semelhantes às das outras mucopolissacárides. O estudo por ressonância magnética do sistema nervoso central pode colaborar no diagnóstico diferencial dessas doenças, avaliar a extensão das lesões e ajudar no controle evolutivo.

  5. Reimplante intencional en diente geminado con lesión endoperio tipo IV: Reporte de caso Intentional replantation gemina injured in tooth type IV endoperio: Case report

    Directory of Open Access Journals (Sweden)

    R.S. Rodríguez Rodríguez

    2012-10-01

    Full Text Available En los dientes con geminación y lesiones periapicales no resueltas después de un tratamiento endodóntico se debe pensar no solo en un diagnostico endodóntico sino también periodontal, ya que estos dientes en el intento de separación pueden presentar surcos o fisuras que van desde el borde incisal hasta la raíz convirtiéndose en un canal de comunicación entre la zona apical y la cavidad oral. Para realizar el plan de tratamiento se debe tener en cuenta: sintomatología persistente, posterior a la terapia endodóntica, persistencia de fístula, lesión periapical de gran tamaño, bolsa periodontal, anatomía radicular palatina del órgano dentario (presunto canal palatino, y que la anatomía del diente sea favorable para realizar el procedimiento. La extracción y reimplante intencional es el tratamiento indicado en casos donde el tratamiento endodóntico fracasa y por la anomalía dental, la cirugía periapical también fallaría porque solo se eliminaría la lesión momentáneamente más no la que lo causa que es la comunicación entre la cavidad oral y la zona apical. Sin embargo, se sabe que esta opción de tratamiento puede traer riesgos y beneficios, incluyendo pérdida del diente o una posible anquilosis y con una de tasa de éxito del 42,9%. El presenta caso clínico describe la extracción y reimplante intencional en un diente geminado con una lesión periapical persistente de origen periodontal, con sintomatología y fístula, posterior a tratamiento endodóntico complejo, su evolución y éxito.In teeth with gemination and unresolved periapical lesions after endodontic treatment we must think not only in diagnosis but also periodontal endodontic, as these teeth in the attempt of separation may have grooves or cracks that go from the incisal edge to root becoming a channel of communication between the apical and oral cavity. To make the treatment plan should take into account: persistent symptoms, after endodontic therapy, persistent fistula, large periapical lesions, periodontal pocket, root anatomy of the tooth organ palate (palatine canal alleged and that the anatomy tooth is favorable to perform the procedure. The extraction and intentional replantation is the treatment in cases where the endodontic treatment fails and the anomaly dental periapical surgery also fail because only temporarily remove the lesion but not the cause it is the communication between the oral cavity and apical area. However, it is known that this treatment option can have risks and benefits, including tooth loss or possible ankylosis and with a success rate of 42.9%. The present case report describes the extraction and intentional replantation geminate tooth with a persistent periapical lesion of periodontal origin, with symptoms and fistula, after endodontic treatment complex, its evolution and success.

  6. Reimplante intencional en diente geminado con lesión endoperio tipo IV: Reporte de caso Intentional replantation gemina injured in tooth type IV endoperio: Case report

    OpenAIRE

    R.S. Rodríguez Rodríguez; G. Gaitan Ibarra; A. Díaz Caballero

    2012-01-01

    En los dientes con geminación y lesiones periapicales no resueltas después de un tratamiento endodóntico se debe pensar no solo en un diagnostico endodóntico sino también periodontal, ya que estos dientes en el intento de separación pueden presentar surcos o fisuras que van desde el borde incisal hasta la raíz convirtiéndose en un canal de comunicación entre la zona apical y la cavidad oral. Para realizar el plan de tratamiento se debe tener en cuenta: sintomatología persistente, posterior a ...

  7. Phase IV of Drug Development.

    Science.gov (United States)

    Suvarna, Viraj

    2010-04-01

    Not all Phase IV studies are post-marketing surveillance (PMS) studies but every PMS study is a phase IV study. Phase IV is also an important phase of drug development. In particular, the real world effectiveness of a drug as evaluated in an observational, non-interventional trial in a naturalistic setting which complements the efficacy data that emanates from a pre-marketing randomized controlled trial (RCT). No matter how many patients are studied pre-marketing in a controlled environment, the true safety profile of a drug is characterized only by continuing safety surveillance through a spontaneous adverse event monitoring system and a post-marketing surveillance/non-interventional study. Prevalent practice patterns can generate leads that could result in further evaluation of a new indication via the RCT route or even a signal that may necessitate regulatory action (change in labeling, risk management/minimization action plan). Disease registries are another option as are the large simple hybrid trials. Surveillance of spontaneously reported adverse events continues as long as a product is marketed. And so Phase IV in that sense never ends.

  8. Phase IV of Drug Development

    Directory of Open Access Journals (Sweden)

    Viraj Suvarna

    2010-01-01

    Full Text Available Not all Phase IV studies are post-marketing surveillance (PMS studies but every PMS study is a phase IV study. Phase IV is also an important phase of drug development. In particular, the real world effectiveness of a drug as evaluated in an observational, non-interventional trial in a naturalistic setting which complements the efficacy data that emanates from a pre-marketing randomized controlled trial (RCT. No matter how many patients are studied pre-marketing in a controlled environment, the true safety profile of a drug is characterized only by continuing safety surveillance through a spontaneous adverse event monitoring system and a post-marketing surveillance/non-interventional study. Prevalent practice patterns can generate leads that could result in further evaluation of a new indication via the RCT route or even a signal that may necessitate regulatory action (change in labeling, risk management/minimization action plan. Disease registries are another option as are the large simple hybrid trials. Surveillance of spontaneously reported adverse events continues as long as a product is marketed. And so Phase IV in that sense never ends.

  9. VeVeRa-IV

    NARCIS (Netherlands)

    Evelien Eggink; Debbie Oudijk; Klarita Sadiraj

    2012-01-01

    Original title: VeVeRa-IV The Dutch population is set to age rapidly in the coming years. More and more people will also attain a very great age. This means that the need for home care and care provided in nursing or residential care homes will also increase. As part of the Long-term Care Programme

  10. Plan empresa productora de audiovisuales : La Central Audiovisual y Publicidad

    OpenAIRE

    Arroyave Velasquez, Alejandro

    2015-01-01

    El presente documento corresponde al plan de creación de empresa La Central Publicidad y Audiovisual, una empresa dedicada a la pre-producción, producción y post-producción de material de tipo audiovisual. La empresa estará ubicada en la ciudad de Cali y tiene como mercado objetivo atender los diferentes tipos de empresas de la ciudad, entre las cuales se encuentran las pequeñas, medianas y grandes empresas.

  11. Os distúrbios alimentares na diabetes mellitus tipo 1

    OpenAIRE

    Pereira, Inês Sofia Soares

    2013-01-01

    Introdução: A diabetes mellitus tipo 1 e os distúrbios alimentares são doenças frequentes na adolescência. Em ambas as condições, os pacientes dão uma grande importância ao peso corporal e à dieta. Assim, estima-se que os pacientes com diabetes mellitus tipo 1 tenham uma grande vulnerabilidade para o desenvolvimento de distúrbios alimentares (incluindo a diabulimia, um comportamento compensatório particular), que podem ter repercussões significativas na sua qualidade de vida. Os objectivos de...

  12. Alle har en historie, IV

    DEFF Research Database (Denmark)

    Ydegaard, Torbjørn

    Alle har en historie IV: Pædagogik med Freedom Writers lader et væld af pædagogiske facetter udspringe af den kendte skole-film Freedom Writers’ scener og handlinger. Der er både fokus på en almen tilgang til pædagogik og på Freedom Writer-metodikken, dels gennem de filmscener, der sættes til...

  13. Dieta y estrés oxidativo: cambios precoces en el metabolismo y la expresión de genes en la patogenia de la diabetes tipo 2

    OpenAIRE

    2013-01-01

    La Diabetes Mellitus Tipo 2 (DMT2) es una enfermedad crónica y grave cuyo aumento creciente se relaciona con la adopción de estilos de vida no saludables como dietas inadecuadas, sedentarismo y estrés crónico. Se asocia frecuentemente con otros factores de riesgo cardiovascular como obesidad de tipo central, hipertensión arterial y dislipidemia. Se demostró también la importancia de la distribución corporal del tejido adiposo en el desarrollo de los desórdenes metabólicos tales como la tolera...

  14. Deployable centralizers

    Energy Technology Data Exchange (ETDEWEB)

    Grubelich, Mark C.; Su, Jiann-Cherng; Knudsen, Steven D.

    2017-02-28

    A centralizer assembly is disclosed that allows for the assembly to be deployed in-situ. The centralizer assembly includes flexible members that can be extended into the well bore in situ by the initiation of a gas generating device. The centralizer assembly can support a large load carrying capability compared to a traditional bow spring with little or no installation drag. Additionally, larger displacements can be produced to centralize an extremely deviated casing.

  15. Central móvil de hormigón asfáltico

    Directory of Open Access Journals (Sweden)

    Editorial, Equipo

    1959-11-01

    Full Text Available En números anteriores se han publicado varios tipos de centrales hormigoneras, y entre ellas una para la preparación de hormigones asfálticos. El tipo de Central que se describe ligeramente en este trabajo, de la casa Braham Patterson & Benham Ltd, inglesa, presenta su particularidad propia e interés dentro del campo de rendimiento de producción del orden de 25 toneladas por hora.

  16. Test Review: Advanced Clinical Solutions for WAIS-IV and WMS-IV

    Science.gov (United States)

    Chu, Yiting; Lai, Mark H. C.; Xu, Yining; Zhou, Yuanyuan

    2012-01-01

    The authors review the "Advanced Clinical Solutions for WAIS-IV and WMS-IV". The "Advanced Clinical Solutions (ACS) for the Wechsler Adult Intelligence Scale-Fourth Edition" (WAIS-IV; Wechsler, 2008) and the "Wechsler Memory Scale-Fourth Edition" (WMS-IV; Wechsler, 2009) was published by Pearson in 2009. It is a…

  17. Test Review: Advanced Clinical Solutions for WAIS-IV and WMS-IV

    Science.gov (United States)

    Chu, Yiting; Lai, Mark H. C.; Xu, Yining; Zhou, Yuanyuan

    2012-01-01

    The authors review the "Advanced Clinical Solutions for WAIS-IV and WMS-IV". The "Advanced Clinical Solutions (ACS) for the Wechsler Adult Intelligence Scale-Fourth Edition" (WAIS-IV; Wechsler, 2008) and the "Wechsler Memory Scale-Fourth Edition" (WMS-IV; Wechsler, 2009) was published by Pearson in 2009. It is a clinical tool for extending the…

  18. Report on the O IV and S IV lines observed by IRIS

    CERN Document Server

    Young, Peter R

    2015-01-01

    The O IV intercombination lines observed by the Interface Region Imaging Spectrograph (IRIS) between 1397 and 1407 A provide useful density diagnostics. This document presents data that address two issues related to these lines: (1) the contribution of S IV to the O IV 1404.8 line; and (2) the range of sensitivity of the O IV 1399.8/1401.2 ratio.

  19. Hindbrain DPP-IV inhibition improves glycemic control and promotes negative energy balance.

    Science.gov (United States)

    Mietlicki-Baase, Elizabeth G; McGrath, Lauren E; Koch-Laskowski, Kieran; Krawczyk, Joanna; Pham, Tram; Lhamo, Rinzin; Reiner, David J; Hayes, Matthew R

    2017-01-22

    The beneficial glycemic and food intake-suppressive effects of glucagon-like peptide-1 (GLP-1) have made this neuroendocrine system a leading target for pharmacological approaches to the treatment of diabetes and obesity. One strategy to increase the activity of endogenous GLP-1 is to prevent the rapid degradation of the hormone by the enzyme dipeptidyl peptidase-IV (DPP-IV). However, despite the expression of both DPP-IV and GLP-1 in the brain, and the clear importance of central GLP-1 receptor (GLP-1R) signaling for glycemic and energy balance control, the metabolic effects of central inhibition of DPP-IV activity are unclear. To test whether hindbrain DPP-IV inhibition suppresses blood glucose, feeding, and body weight gain, the effects of 4th intracerebroventricular (ICV) administration of the FDA-approved DPP-IV inhibitor sitagliptin were evaluated. Results indicate that hindbrain delivery of sitagliptin improves glycemic control in a GLP-1R-dependent manner, suggesting that this effect is due at least in part to increased endogenous brainstem GLP-1 activity after sitagliptin administration. Furthermore, 4th ICV injection of sitagliptin reduced 24h body weight gain and energy intake, with a selective suppression of high-fat diet, but not chow, intake. These data reveal a novel role for hindbrain GLP-1R activation in glycemic control and also demonstrate that DPP-IV inhibition in the caudal brainstem promotes negative energy balance.

  20. CARACTERIZAÇÃO PÓS-COLHEITA E SENSORIAL DE GENÓTIPOS DE BANANEIRAS TIPO PRATA

    Directory of Open Access Journals (Sweden)

    ARIANE CASTRICINI

    2015-03-01

    Full Text Available RESUMO O norte de Minas Gerais é grande produtor de banana ‘Prata-Anã’ irrigada, cultura altamente suscetível ao Mal-do-Panamá. O uso de genótipos resistentes é uma alternativa, mas os frutos devem apresentar características pós-colheita o mais próximo possível da ‘Prata-Anã’, para melhor aceitação pelos consumidores. O objetivo do trabalho foi caracterizar frutos em pós-colheita, identificar a preferência e a intenção de compra de diferentes genótipos de bananeira tipo Prata. Os genótipos Prata-Anã, BRS Platina e Fhia-18. foram caracterizados no ponto de colheita (verdes e maduros (estádio seis de maturação, por avaliações químicas, físicas e sensoriais. Quando verde, ‘BRS Platina’ apresentou maior massa fresca e tamanho que ‘Fhia-18’ e ‘Prata-Anã’. ‘Fhia-18.’ teve a tonalidade verde da casca mais intensa que a dos demais genótipos. Madura, ‘BRS Platina’ foi mais firme, mas com a mesma resistência ao despencamento que ‘Fhia-18’ e superior à ‘Prata-Anã’. ‘Fhia-18’ apresentou cor da casca com amarelo mais clara e tão brilhante quanto da ‘Prata-Anã’, mas ‘BRS Platina’ teve a tonalidade de amarelo mais intensa. Bananas ‘Fhia-18’ foram mais ácidas, ‘BRS Platina’, com menor acidez titulável, e ‘Prata-Anã’, o maior teor de sólidos solúveis. Os genótipos Prata-Anã e BRS Platina tiveram maior preferência e intenção de compra pelos consumidores, sendo as bananas ‘Prata-Anã’ em dedos e ‘BRS Platina’ e ‘Fhia-18’ em dedos, buquê e penca, as mais preferidas. Entretanto, a maioria compraria bananas ‘Prata-Anã’ em buquê e ‘BRS Platina’ e ‘Fhia-18’ em penca. Enquanto verdes, os genótipos foram semelhantes à ‘Prata-Anã’, e maiores diferenças químicas e físicas ocorreram quando maduros.

  1. ANÁLISIS DIALÉLICO DEL RENDIMIENTO DE CHILE POR EL MÉTODO IV DE GRIFFING

    Directory of Open Access Journals (Sweden)

    Mirna Hern\\u00E1ndez-P\\u00E9rez

    2011-01-01

    Full Text Available El objetivo de este trabajo fue estimar la aptitud combinatoria general de genotipos de chile y la aptitud combinatoria específica de sus cruzas directas. Se utilizó el método IV modelo fijo de Griffing, con la finalidad de definir el esquema de mejoramiento genético. Los cruzamientos se realizaron en invernadero en la Universidad Autónoma Agraria Antonio Narro (UAAN, en Saltillo, Coahuila. La evaluación se realizó en el Campo Experimental Huastecas, Instituto Nacional de Investigaciones Forestales, Agrícolas y Pecuarias (INIFAP, Villa Cuauhtémoc, Tamaulipas, en el ciclo otoño-invierno de 2008. Se utilizaron seis tipos de chile tres tipo jalapeño (4, 6 y 118, tipo húngaro amarillo (8, uno tipo ancho (16 y uno tipo mulato. Se evaluó la progenie de seis cruzas directas, para días a floración y días a corte, y rendimiento de frutos por plantas, diámetro, longitud y peso promedio del fruto y rendimiento por hectárea. Los mejores genotipos fueron 6 y 16, por su mayor aptitud combinatoria general, y las mejores cruzas por su aptitud combinatoria específica fueron 6x16 y 4x6, la cruza 16x118 mostró alto rendimiento.

  2. IVS contribution to ITRF2014

    Science.gov (United States)

    Bachmann, Sabine; Thaller, Daniela; Roggenbuck, Ole; Lösler, Michael; Messerschmitt, Linda

    2016-07-01

    Every few years the International Terrestrial Reference System (ITRS) Center of the International Earth Rotation and Reference Systems Service (IERS) decides to generate a new version of the International Terrestrial Reference Frame (ITRF). For the upcoming ITRF2014 the official contribution of the International VLBI Service for Geodesy and Astrometry (IVS) comprises 5796 combined sessions in SINEX file format from 1979.6 to 2015.0 containing 158 stations, overall. Nine AC contributions were included in the combination process, using five different software packages. Station coordinate time series of the combined solution show an overall repeatability of 3.3 mm for the north, 4.3 mm for the east and 7.5 mm for the height component over all stations. The minimum repeatabilities are 1.5 mm for north, 2.1 mm for east and 2.9 mm for height. One of the important differences between the IVS contribution to the ITRF2014 and the routine IVS combination is the omission of the correction for non-tidal atmospheric pressure loading (NTAL). Comparisons between the amplitudes of the annual signals derived by the VLBI observations and the annual signals from an NTAL model show that for some stations, NTAL has a high impact on station height variation. For other stations, the effect of NTAL is low. Occasionally other loading effects have a higher influence (e.g. continental water storage loading). External comparisons of the scale parameter between the VTRF2014 (a TRF based on combined VLBI solutions), DTRF2008 (DGFI-TUM realization of ITRS) and ITRF2008 revealed a significant difference in the scale. A scale difference of 0.11 ppb (i.e. 0.7 mm on the Earth's surface) has been detected between the VTRF2014 and the DTRF2008, and a scale difference of 0.44 ppb (i.e. 2.8 mm on the Earth's surface) between the VTRF2014 and ITRF2008. Internal comparisons between the EOP of the combined solution and the individual solutions from the AC contributions show a WRMS in X- and Y-Pole between

  3. Vaciamiento gástrico y diabetes mellitus tipo 2

    Directory of Open Access Journals (Sweden)

    Camilo Andrés Quintero-Cadavid

    2015-04-01

    Full Text Available El adecuado control de la diabetes mellitus tiene una gran importancia desde muchos puntos de vista. En los últimos años, se ha destacado el impacto que tienen los niveles de la glucemia postprandial sobre el manejo y las complicaciones de esta enfermedad. Controlar la hiperglucemia postprandial y, por lo tanto, su participación en el deterioro clínico de los pacientes con diabetes puede conseguirse retardando el vaciamiento gástrico y estimulando el efecto incretina, los cuales se pueden promover utilizando los análogos del péptido similar al glucagón tipo 1 (GLP-1. En este artículo se revisa el concepto del efecto incretina y la utilidad de los análogos GLP-1 en el control de la glicemia en los pacientes con diabetes mellitus tipo 2.

  4. Sobre la localidad tipo de Eunectes notaeus Cope (Serpentes: Boidae

    Directory of Open Access Journals (Sweden)

    Waller, Tomás

    2000-02-01

    Full Text Available Todas las revisiones han pasado por alto el hecho de que el mismo de la descripción, al detallar el catálogo de la colección realizada durante la expedición conducida por el Capitán T. J. Page en los ríos Paraná, Paraguay, Bermejo y Uruguay, E. D. Cope especifica claramente el lugar de procedencia del especimen tipo: "...No. 4707. Taken in the Paraguay River about thirty miles south of Fort Coimbra, Brazil, near lat. 20°S" (Cope, 1862b: 350. En definitiva, esta última debería ser considerada la localidad tipo de E. notaeus.

  5. Efectos del tipo funcional de entrenamiento sobre el ajuste lector

    OpenAIRE

    Rosalinda Arroyo Hernández; Guadalupe Mares Cárdenas

    2009-01-01

    El presente trabajo tuvo por objetivo evaluar los efectos de entrenar cinco tipos de contacto con las relaciones entre objetos y sus elaboraciones lingüísticas sobre el ajuste lector de estudiantes universitarios. Primeramente los participantes fueron expuestos a una evaluación de ajuste lector, consistente en preguntas de diferente complejidad funcional, para posteriormente ser asignados aleatoriamente a uno de cinco grupos experimentales diferenciados por el nivel de complejidad funcional d...

  6. Estimulantes tipo-anfetamínicos : uma abordagem no trânsito, analítica e forense

    OpenAIRE

    2013-01-01

    A utilização de substâncias estimulantes tipo-anfetamínicos (ATS) por motoristas com objetivo de aumentar o tempo de vigília é um conhecido problema nacional com consequências sociais e legais. A dietilpropiona (DIE) e o femproporex (FEN) figuram entre os estimulantes do sistema nervoso central (SNC) mais utilizados por condutores no trânsito brasileiro. O metilfenidato (MPH) é um fármaco que apresenta propriedades similares à cocaína e à anfetamina (AMP). Sua utilização como droga de rua e r...

  7. Neurofibromatosis tipo 1 en el embarazo: reporte de caso y revisión de la literatura

    OpenAIRE

    2016-01-01

    Introducción: La combinación de embarazo y Neurofibromatosis tipo 1 (NF1) ha sido reportada con frecuencias de 1/2.500 a 1/18.500 partos. Patología con manifestaciones que van desde lesiones cutáneas, tumores o complicaciones ortopédicas. En la mujer esta enfermedad podría empeorar durante la gestación, debido a la cantidad de receptores esteroidales que tendrían los neurofibromas y la posibilidad de malignización de tumores del sistema nervioso central. Presentación del Caso: Mujer de 22 año...

  8. Applying the Fe(III) binding property of a chemical transferrin mimetic to Ti(IV) anticancer drug design.

    Science.gov (United States)

    Parks, Timothy B; Cruz, Yahaira M; Tinoco, Arthur D

    2014-02-03

    As an endogenous serum protein binder of Ti(IV), transferrin (Tf) serves as an excellent vehicle to stabilize the hydrolysis prone metal ion and successfully transport it into cells. This transporting role is thought to be central to Ti(IV)'s anticancer function, but efforts to synthesize Ti(IV) compounds targeting transferrin have not produced a drug. Nonetheless, the Ti(IV) transferrin complex (Ti2Tf) greatly informs on a new Ti(IV)-based anticancer drug design strategy. Ti2Tf interferes with cellular uptake of Fe(III), which is particularly detrimental to cancer cells because of their higher requirement for iron. Ti(IV) compounds of chemical transferrin mimetic (cTfm) ligands were designed to facilitate Ti(IV) activity by attenuating Fe(III) intracellular levels. In having a higher affinity for Fe(III) than Ti(IV), these ligands feature the appropriate balance between stability and lability to effectively transport Ti(IV) into cancer cells, release Ti(IV) via displacement by Fe(III), and deplete the intracellular Fe(III) levels. The cTfm ligand N,N'-di(o-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid (HBED) was selected to explore the feasibility of the design strategy. Kinetic studies on the Fe(III) displacement process revealed that Ti(IV) can be transported and released into cells by HBED on a physiologically relevant time scale. Cell viability studies using A549 cancerous and MRC5 normal human lung cells and testing the cytotoxicity of HBED and its Ti(IV), Fe(III), and Ga(III) compounds demonstrate the importance of Fe(III) depletion in the proposed drug design strategy and the specificity of the strategy for Ti(IV) activity. The readily derivatized cTfm ligands demonstrate great promise for improved Ti(IV) anticancer drugs.

  9. A IDENTIFICAÇÃO DE TIPOS DE LIDERANÇA A PARTIR DE ARQUÉTIPOS

    Directory of Open Access Journals (Sweden)

    Adriana Nunes Lacerda e Prestupa

    2009-09-01

    junguianos analisados por Moore e Gillette (1993 foram relacionados com características de líderes dentro do contexto organizacional. Desta forma foi possível apresentar uma tipologia rica e aplicável, onde o individuo pode se identificar e também entender o processo e a maturação das características dos arquétipos estudados para melhor desempenho dentro das organizações.

  10. La ficción de Iván Molina Jiménez (Science Fiction by Iván Molina Jiménez

    Directory of Open Access Journals (Sweden)

    Roy Alfaro Vargas

    2014-11-01

    Full Text Available El estudio analiza la narrativa de ciencia ficción de Iván Molina Jiménez, a partir de un cuerpo teórico para abordar el análisis y la producción literaria de ciencia ficción, desde una adecuada poiesis. Se plantean los principios alrededor de la noción de novum, para la producción literaria de este tipo. Luego, se analizan algunos textos de ciencia ficción de Molina, y se muestran deficiencias de tal producción para así iniciar la construcción de las bases de la ciencia ficción costarricense. This article analyzes the tales of science fiction by Iván Molina Jiménez using a theoretical framework which makes it possible to address the literary production of science fiction, from the perspective of an adequate poiesis. The necessary principles based on the notion of novum are proposed for this genre. Then, some texts of science fiction by Iván Molina are analyzed, indicating certain deficiencies in order to begin the construction of the basis of the Costa Rican science fiction.

  11. Qualidade sanitária de grãos de soja tipo alimento

    OpenAIRE

    Ronaldo, Adilson Bizzeto; Universidade Estadual de Londrina; Levy, Mauricio; Universidade Estadual de Londrina; Homechin, Martin; Universidade Estadual de Londrina; Destro, Deonisio; Universidade Estadual de Londrina; Miranda, Lilian Azevedo; Universidade Estadual de Londrina

    1996-01-01

    O objetivo foi quantificar a incidência de fungos em grãos de soja (Glycine max ( L.) Merrill) provenientes de cruzamentos de soja tipo alimento com soja tipo grão. A soja tipo alimento inclui a soja com sementes grandes, com peso de cem sementes (PCS) igual ou maior que 20 gramas (soja tipo hortaliça) e a soja com sementes pequenas, com PCS menor que 10 gramas (soja para consumo na forma de brotos ou "natto"). A soja tipo grão tem sementes de tamanho médio, com PCS entre 10 e 19 gramas, e é ...

  12. Structural Basis of DNA Ligase IV-Artemis Interaction in Nonhomologous End-Joining

    Directory of Open Access Journals (Sweden)

    Pablo De Ioannes

    2012-12-01

    Full Text Available DNA ligase IV (LigIV and Artemis are central components of the nonhomologous end-joining (NHEJ machinery that is required for V(DJ recombination and the maintenance of genomic integrity in mammalian cells. We report here crystal structures of the LigIV DNA binding domain (DBD in both its apo form and in complex with a peptide derived from the Artemis C-terminal region. We show that LigIV interacts with Artemis through an extended hydrophobic surface. In particular, we find that the helix α2 in LigIV-DBD is longer than in other mammalian ligases and presents residues that specifically interact with the Artemis peptide, which adopts a partially helical conformation on binding. Mutations of key residues on the LigIV-DBD hydrophobic surface abolish the interaction. Together, our results provide structural insights into the specificity of the LigIV-Artemis interaction and how the enzymatic activities of the two proteins may be coordinated during NHEJ.

  13. IVS Working Group 4: VLBI Data Structures

    Science.gov (United States)

    Gipson, John

    2010-01-01

    In 2007 the IVS Directing Board established IVS Working Group 4 on VLBI Data Structures. This note discusses the current VLBI data format, goals for a new format, the history and formation of the Working Group, and a timeline for the development of a new VLBI data format.

  14. Stark broadening of B IV spectral lines

    CERN Document Server

    Dimitrijevic, Milan S; Simic, Zoran; Kovacevic, Andjelka; Sahal-Brechot, Sylvie

    2016-01-01

    Stark broadening parameters for 157 multiplets of helium like boron (B IV) have been calculated using the impact semiclassical perturbation formalism. Obtained results have been used to investigate the regularities within spectral series. An example of the influence of Stark broadening on B IV lines in DO white dwarfs is given.

  15. Metsahovi Radio Observatory - IVS Network Station

    Science.gov (United States)

    Uunila, Minttu; Zubko, Nataliya; Poutanen, Markku; Kallunki, Juha; Kallio, Ulla

    2013-01-01

    In 2012, Metsahovi Radio Observatory together with Finnish Geodetic Institute officially became an IVS Network Station. Eight IVS sessions were observed during the year. Two spacecraft tracking and one EVN X-band experiment were also performed. In 2012, the Metsahovi VLBI equipment was upgraded with a Digital Base Band Converter, a Mark 5B+, a FILA10G, and a FlexBuff.

  16. ACME-III and ACME-IV Final Campaign Reports

    Energy Technology Data Exchange (ETDEWEB)

    Biraud, S. C. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2016-01-01

    The goals of the Atmospheric Radiation Measurement (ARM) Climate Research Facility’s third and fourth Airborne Carbon Measurements (ACME) field campaigns, ACME-III and ACME-IV, are: 1) to measure and model the exchange of CO2, water vapor, and other greenhouse gases by the natural, agricultural, and industrial ecosystems of the Southern Great Plains (SGP) region; 2) to develop quantitative approaches to relate these local fluxes to the concentration of greenhouse gases measured at the Central Facility tower and in the atmospheric column above the ARM SGP Central Facility, 3) to develop and test bottom-up measurement and modeling approaches to estimate regional scale carbon balances, and 4) to develop and test inverse modeling approaches to estimate regional scale carbon balance and anthropogenic sources over continental regions. Regular soundings of the atmosphere from near the surface into the mid-troposphere are essential for this research.

  17. Síndrome de Waardenburg tipo I: relato de caso

    Directory of Open Access Journals (Sweden)

    Patricia Capua Vieira da Silva

    2011-06-01

    Full Text Available A síndrome de Waardenburg tipo I é uma desordem auditivo-pigmentária que inclui, entre outros, perda auditiva neurossensorial congênita não progressiva, telecanto, distúrbios pigmentares de íris, cabelo e pele. Indivíduos afetados podem ter maior risco de: defeitos no tubo neural, fendas labial e palatina, anormalidades nos membros e doença de Hirschsprung. O diagnóstico é clínico, sendo necessários dois critérios maiores ou um maior e dois menores. PAX3 é o único gene conhecido associado à síndrome, sendo, entretanto, mais usado no aconselhamento genético. Quanto ao diagnóstico diferencial, podemos citar: outras causas de perda auditiva neurossensorial congênita não progressiva, outros tipo de síndrome de Waardenburg, piebaldismo, albinismo, vitiligo e síndrome de Teitz. Neste trabalho, apresenta-se um paciente masculino de 11 anos com diagnóstico de síndrome de Waardenburg tipo I. Ressalta-se a importância do oftalmologista no auxílio do diagnóstico deste raro quadro sistêmico, uma vez que inclui algumas alterações oftalmológicas. O diagnóstico precoce da síndrome permite estimulação adequada para a perda auditiva, assim como medidas preventivas em caso de gestantes afetadas no aconselhamento genético.

  18. Thermodynamic data for predicting concentrations of Th(IV), U(IV), Np(IV), and Pu(IV) in geologic environments

    Energy Technology Data Exchange (ETDEWEB)

    Rai, Dhanpat; Roa, Linfeng; Weger, H.T.; Felmy, A.R. [Battelle, Pacific Northwest National Laboratory (PNNL) (United States); Choppin, G.R. [Florida State University (United States); Yui, Mikazu [Waste Isolation Research Division, Tokai Works, Japan Nuclear Cycle Development Inst., Tokai, Ibaraki (Japan)

    1999-01-01

    This report provides thermodynamic data for predicting concentrations of Th(IV), U(IV), Np(IV), and Pu(IV) in geologic environments, and contributes to an integration of the JNC chemical thermodynamic database, JNC-TDB (previously PNC-TDB), for the performance analysis of geological isolation system for high-level radioactive wastes. Thermodynamic data for the formation of complexes or compounds with hydroxide, chloride, fluoride, carbonate, nitrate, sulfate and phosphate are discussed in this report. Where data for specific actinide(IV) species was lacking, the data were selected based on chemical analogy to other tetravalent actinides. In this study, the Pitzer ion-interaction model is used to extrapolate thermodynamic constants to zero ionic strength at 25degC. (author)

  19. Actividad física y diabetes mellitus tipo 2

    OpenAIRE

    Blanca Estela Bastidas Ramírez; Jesús Javier García Bañuelos; Ana Rosa Rincón Sánchez; Arturo Panduro Cerda

    2001-01-01

    Los efectos del ejercicio sobre el metabolismode la glucosa y los lípidos han sido plenamentecomprobados, por lo que se debería considerarcomo medida terapéutica y preventiva de la diabetes mellitus tipo 2. El ejercicio produce unefecto inmediato sobre la captación de glucosa, que perdura hasta por 2 hrs, provocado porla translocación de receptores GLUT4 a la membrana plasmática de músculo esquelético, pormecanismos diferentes a los desencadenadospor insulina. Además, se presenta un efecto ta...

  20. Manejo nutricio del adulto con diabetes mellitus tipo 2

    OpenAIRE

    Claudia Hunot Alexander

    2001-01-01

    El manejo nutricio del adulto con diabetes tipo2, es la parte angular en el tratamiento de esta enfermedad. Es un proceso que requiere de unconocimiento profundo de nutrición y alimenta-ción, en donde el profesional de la salud recibeun entrenamiento a profundidad en esta áreacon la finalidad de transmitir esta información alos pacientes. El establecimiento de un plan decuidado nutricio, implementado a través del pro-ceso de terapia médico nutrimental, involucrael trabajo multidisciplinario d...

  1. Tratamiento de la diabetes mellitus tipo 2. Actualidades

    OpenAIRE

    J. Miguel Escalante Pulido

    2001-01-01

    La diabetes mellitus tipo 2 es un grupo de trastornos con complejas anormalidadesmetabólicas. Estas incluyen: elevada producciónde glucosa por el hígado, deficiente secreciónde insulina por el páncreas y una pobre respuestadel organismo hacia la insulina, referido comoresistencia a la insulina. Por lo tanto, una correcta selección de los diferentes fármacos actuales es necesaria para modificar favorablemente los diferentes trastornos de esta enfermedad. Los hipoglucemiantes actuales modifican...

  2. Tipos de humor en la publicidad impresa en Colombia

    OpenAIRE

    Carolina María Cifuentes

    2005-01-01

    Una de las herramientas frecuentemente utilizadas por los publicistas para persuadir es el humor. De ahí el creciente interés por estudiar su influencia en el procesamiento, actitudes y comportamiento de los individuos. Se realizó una revisión de investigaciones sobre humor publicitario y sus efectos en la persuasión, atención, comprensión, actitudes y memoria, así como estudios sobre humor y factores culturales, de audiencia, medios masivos y tipos de producto. Se pre...

  3. Sarcopenia en pacientes con diabetes mellitus tipo 2.

    OpenAIRE

    Vergara Ruiz, José Carlos

    2015-01-01

    El riesgo de discapacidad es mayor en pacientes con diabetes mellitus tipo 2 (DM2). Buena parte del mismo se debe al envejecimiento del músculo esquelético o sarcopenia. El déficit de fuerza muscular asociado a la edad tiene mayor asociación con la pérdida de funcionalidad que el mismo proceso cuando afecta a la masa muscular esquelética, y no ocurren de forma paralela ni proporcional. Recientemente se ha propuesto el término dinapenia para referirse a ésta pérdida de fuerza muscular, con ind...

  4. Alteraciones salivares en pacientes con diabetes tipo 2

    OpenAIRE

    Carda Batalla, María del Carmen; Mosquera Lloreda, Nezly; Salom, Lucas; Gómez de Ferraris, María Elsa; Peydró Olaya, Amando

    2006-01-01

    La diabetes mellitus tipo 2 es el desorden metabólico más frecuente, siendo además causante de una importante morbi-mortalidad. En estos pacientes se han descrito alteraciones estructurales de la parotida (sialosis) que podrían comportar modificaciones en la composición salivar, así como un incremento de patología dental y periodontal. Objetivos: establecer las alteraciones bioquímicas de la saliva y su posible correlación con los hallazgos morfológicos. Diseño del estudio: se realizo u...

  5. "The Shield": un tipo de policía diferente

    OpenAIRE

    García-Martínez, A.N. (Alberto Nahum)

    2013-01-01

    No hay ficción televisiva que se abra y se cierre mejor que The Shield. El primer asalto es salvaje: una crochet de realismo sucio y adrenalina en la jungla de asfalto, una hora que castiga el hígado hasta noquearte. «Lo del poli bueno y el poli malo se acabó por hoy. Yo soy un tipo de policía diferente», clama Vic Mackey antes de partirle los dientes a un pederasta en la sala de interrogación. Como el protagonista, The Shield (FX, 2002-08) también es un relato diferente, arriesgado, que...

  6. Sistemas de tipos en lenguajes lógico-funcionales

    OpenAIRE

    2013-01-01

    La programación lógico-funcional es un paradigma de programación declarativa muy expresivo, fruto de la combinación de la programación funcional y la programación lógica. Entre sus principales características destacan la posibilidad de de1nir funciones indeterministas, los patrones de orden superior y el uso de variables libres que se ligan a valores adecuados durante el cómputo. Desde el punto de vista de tipos, los sistemas lógico-funcionales han adoptado demaneradirectaelsistemadetiposdeDa...

  7. INTEGRACION DE UNA CELULA FLEXIBLE DE MECANIZADO, DE TIPO DOCENTE

    OpenAIRE

    2007-01-01

    Este trabajo trata sobre la integración de una célula flexible de mecanizado de tipo docente, compuesta por una fresadora didáctica CNC, marca Denford, un brazo robótico articulado de seis ejes, modelo Scorbot -ER Vplus  y un riel deslizante; todos pertenecientes al Laboratorio de Manufactura Integrada por Computador, de la Escuela de Ingeniería Mecánica de la Universidad de Talca. Las tareas que realiza esta célula flexible son controladas por un PC director  a través de un  programa, utiliz...

  8. Apoptosis neuronal: la diversidad de señales y de tipos celulares

    Directory of Open Access Journals (Sweden)

    Lina Vanessa Becerra

    2009-03-01

    Full Text Available La muerte celular programada es un evento fisiológico durante el desarrollo. En el encéfalo y la médula espinal, este proceso determina el número y la localización de los diferentes tipos celulares. En el sistema nervioso del adulto, la muerte celular programada o apoptosis está más restringida, pero puede jugar un papel determinante en enfermedades crónicas o agudas. Al contrario de otros tejidos en los cuales la apoptosis está documentada ampliamente desde el punto de vista morfológico, en el sistema nervioso central la evidencia en este sentido es escasa. A pesar de esto, existe consenso acerca de la activación de diferentes sistemas de señalización apoptótica. En el presente artículo se intenta resumir las principales vías de señalización apoptótica identificadas en el tejido nervioso. Considerando que las vías apoptóticas son múltiples, los tipos neuronales diversos y especializados y que la respuesta neuronal a la lesión y la supervivencia dependen del contexto de la célula en el tejido (preservación de la conectividad, integridad glial y matriz extracelular, flujo sanguíneo y disponibilidad de factores tróficos, lo que es relevante en el proceso apoptótico en un sector del cerebro puede no serlo en otro.

  9. Marginal adaptation of large adhesive class IV composite restorations before and after artificial aging

    NARCIS (Netherlands)

    Ardu, S.; Stavridakis, M.; Feilzer, A.J.; Krejci, I.; Lefever, D.; Dietschi, D.

    2011-01-01

    Purpose: To test the marginal adaptation of Class IV restorations made of different composite materials designed for anterior use. Materials and Methods: Forty-two extracted caries-free human maxillary central incisors were randomly divided into 7 experimental groups - one per composite tested - for

  10. European Energy Law. Report IV

    Energy Technology Data Exchange (ETDEWEB)

    Hammer, U.; Roggenkamp, M.M. (eds.)

    2007-07-01

    The European Energy Law Report IV presents an overview of the most important legal developments in the field of EU and national energy law as discussed at the 2006 European Energy Law Seminar. It examines recent developments in EU and National Law affecting the energy sector. This includes the increasing use of EU competition law to liberalise the energy markets, the long-awaited implementation of the 2003 Electricity and Gas Directives in Germany and an assessment of Regulation 1775/2005 and its effect on the European gas market. Besides the energy market liberalisation, the Community is increasingly paying attention to the need for a sustainable and clean energy supply. The second part of the book therefore includes chapters on legal issues resulting from the experiences on emission trading in 2005-2007, the regulatory challenges resulting from the new Commission Energy Policy, the impact of the Amsterdam and Berlin Fora on EU Energy policy, and the EU policy framework on energy efficiency. An important tool for improving energy efficiency is the introduction of white certificates. The third part of the report presents the basic principles of white certificates as well as practical experiences and policies in some member states like Italy, France, The Netherlands and the UK. The final part of the report considers several issues related to the development and use of subsea electricity interconnectors and pays special attention to the development of the NorNed cable. It raises the need for a Treaty perspective on the developments of such subsea interconnectors. Then some regulatory views on the development of the NorNed cable and market coupling through the cable are presented. Finally, the economic and regulatory distinction between regulated and merchant interconnectors is discussed.

  11. GALACTIC KINEMATICS OF PLANETARY NEBULAE WITH [WC] CENTRAL STAR

    Directory of Open Access Journals (Sweden)

    Miriam Peña

    2013-01-01

    Full Text Available Usando espectros de alta resolución, analizamos la distribución y cinemática galáctica de nebulosas planetarias con estrella central [WR] y ‘wels’ ([WR]PN y WLPN. Se calcularon las velocidades circulares y peculiares (Vpec de los objetos, y obtuvimos que: (a Las [WR]PNe pertenecen al disco galáctico y están más concentradas que las WLPNe y PN normales, lo que corresponde a objetos más jóvenes. (b Clasificamos la muestra en Tipos de Peimbert y encontramos que las PNe de Tipo I tienen Vpec ˂ 50 km s−1, como corresponde a objetos jóvenes; la mayoría de las [WR]PN son del Tipo II con Vpec ˂ 60 km s−1, aunque un porcentaje de la muestra es del Tipo III con Vpec más alta, lo que indica que el fenómeno Wolf- Rayet en estrellas centrales puede ocurrir con cualquier masa estelar y en objetos viejos. Ninguna WLPN de la muestra es Tipo I. Así [WR]PNe y WLPNe no están relacionados.

  12. Memoria larga en el tipo de cambio nominal: evidencia internacional

    Directory of Open Access Journals (Sweden)

    Héctor F. Salazar Núnez

    2015-01-01

    Full Text Available En este trabajo se examina la dinámica del tipo de cambio con respecto del dólar americano para varias economías, desarrolladas y en vías de desarrollo, con el fin de encontrar evidencia de memoria larga durante el periodo 1971-2012. Para ello se aplican lassiguientes pruebas: coeficiente de Hurst, correlograma, gráfico de la varianza, Geweke y Porter-Hudak, así como estimador local de Whittle de Robinson. Al respecto, Chile, China, Islandia, Israel, México y Turquía presentaron evidencia de memoria larga de acuerdo con pruebas consistentes y, en consecuencia, se estimó para ellos un modelo Autorregresivo Fraccionalmente Integrado con Medias Móviles en los dominios del tiempo y la frecuencia. En el dominio del tiempo se empleó el método de máxima verosimilitud (Sowell, 1992, y en el dominio de la frecuencia se utilizó la técnica de Fox y Taqqu (1986. Los resultados del modelo Autorregresivo Fraccionalmente Integrado con Medias Móviles muestran que Chile, China, Islandia y México presentan evidencia de memoria larga en el tipo de cambio; el método de estimación que presenta el mejor ajuste a la curva original es el método de máxima verosimilitud exacta de acuerdo con el criterio de información de Akaike.

  13. Ocorrência de Staphylococcus aureus em queijo tipo "frescal"

    Directory of Open Access Journals (Sweden)

    Almeida Filho Edvaldo Sampaio de

    2000-01-01

    Full Text Available OBJETIVO: Verificar a ocorrência de Staphylococcus aureus em uma amostra de queijo tipo Minas "frescal" comercializado na cidade de Poços de Caldas, MG, de modo a obter subsídios que permitam avaliar o risco potencial que este produto pode representar para a saúde da população consumidora. MÉTODOS: Foi investigada a presença e o número de cepas de Staphylococcus aureus em 80 amostras de queijo tipo Minas "frescal" produzido artesanalmente e comercializado na cidade de Poços de Caldas, MG, Brasil. RESULTADOS: Os resultados obtidos evidenciaram a presença de S. aureus em 40 (50,0% amostras, cujas contagens revelaram valores médios em torno de 10(5/g. CONCLUSÕES: Tais achados parecem ser extremamente preocupantes, pois além de se situarem acima do limite máximo de 10³/g estabelecido pelo Ministério da Saúde, estes valores mostraram-se muito próximos dos requeridos para a produção de enterotoxinas em quantidades suficientes para a ocorrência de surtos de intoxicação alimentar estafilocócica.

  14. Surprising Coordination Geometry Differences in Ce(IV)- and Pu(IV)-Maltol Complexes

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence Berkeley National Laboratory; Raymond, Kenneth; Szigethy, Geza; Xu, Jide; Gorden, Anne E.V.; Teat, Simon J.; Shuh, David K.; Raymond, Kenneth N.

    2008-02-12

    As part of a study to characterize the detailed coordination behavior of Pu(IV), single crystal X-ray diffraction structures have been determined for Pu(IV) and Ce(IV) complexes with the naturally-occurring ligand maltol (3-hydroxy-2-methyl-pyran-4-one) and its derivative bromomaltol (5-bromo-3-hydroxy-2-methyl-pyran-4-one). Although Ce(IV) is generally accepted as a structural analog for Pu(IV), and the maltol complexes of these two metals are isostructural, the corresponding bromomaltol complexes are strikingly different with respect to ligand orientation about the metal ion: All complexes exhibit trigonal dodecahedral coordination geometry but the Ce(IV)-bromomaltol complex displays an uncommon ligand arrangement not mirrored in the Pu(IV) complex, although the two metal species are generally accepted to be structural analogs.

  15. Las copas tipo Cástulo en la Península Ibérica

    Directory of Open Access Journals (Sweden)

    Sánchez, Carmen

    1992-12-01

    Full Text Available The Castulo cup is one of the most common black glaze Attic forms in the Iberian Peninsula from the Atlantic coast to Ampurias. Their date in the Iberian Peninsula is some years later than that proposed for Athens. They did not appear till some years after the second half of the 5th c. B.C. Their production probably continued until the first quarter of the 4th century B.C. They are almost fixed in their form for about a century, but some differences in the outside decoration and the underside of the foot can be pointed out. Two main types are proposed for the second half of the 5th century and the first quarter of the 4th century B.C. The differences in date compared with those found at Athens can be explained as an adaptation of the workshops to the demands of Iberian customers. Athen's artisans continued making Castulo cups for export at a time when in Athens they did not use them any more, because the stemless cup had been replaced by the popular kantharoi and cup-kantharoi.

    La copa Cástulo es una de las formas áticas de barniz negro más abundante en los yacimientos peninsulares desde la costa atlántica hasta Ampurias. Su cronología es en la Península Ibérica algo posterior a la propuesta para Atenas. No aparecen hasta algo después de mediados del siglo V y probablemente se continúan fabricando hasta el primer cuarto del IV a. C. No experimentan durante casi un siglo de producción ninguna variación formal, sin embargo sí se pueden ver diferencias en el tratamiento de la decoración exterior y del fondo externo. Se proponen aquí fundamentalmente dos tipos de la segunda mitad del siglo V y primer cuarto del IV a. C. La diferencia cronológica con las halladas en Atenas se explica como una adaptación de los talleres áticos a la demanda de los clientes ibéricos. Los artesanos atenienses continúan fabricando copas Cástulo para la exportación cuando en Atenas se han dejado ya de utilizar las copas de pie bajo al ser

  16. Atmosphere of Mars - Mariner IV models compared.

    Science.gov (United States)

    Eshleman, V. R.; Fjeldbo, G.; Fjeldbo, W. C.

    1966-01-01

    Mariner IV models of three Mars atmospheric layers analogous to terrestrial E, F-1 and F-2 layers, considering relative mass densities, temperatures, carbon dioxide photodissociation and ionization profile

  17. Periodontal Disease Part IV: Periodontal Infections

    OpenAIRE

    Turnbull, Robert S.

    1988-01-01

    In Part IV of this article, the author describes two periodontal infections, acute necrotizing ulcerative gingivitis (trench mouth) and periodontal abscess, both acute painful conditions for which patients may seek advice from their family physician rather than their dentist.

  18. A ultra-sonografia do pâncreas é eficaz em diagnosticar o diabete melito tipo 1 e tipo 2?

    Directory of Open Access Journals (Sweden)

    Pimenta Walkyria de Paula

    2002-01-01

    Full Text Available Este trabalho foi realizado para verificar se a ultra-sonografia do pâncreas oferece dados auxiliares na classificação de diabéticos adultos dos tipos 1 e 2. O tamanho e a ecogenicidade do pâncreas foram determinados pela ultra-sonografia em 81 diabéticos, sendo 20 do tipo 1 e 61 do tipo 2 (53 obesos e oito não-obesos. Os pacientes tipo 2 obesos diferiram dos demais por apresentarem área total e diâmetro ântero-posterior do corpo do pâncreas significativamente maiores. Quanto à ecogenicidade pancreática, esta estava aumentada com maior freqüência nos diabéticos tipo 2 obesos que nos diabéticos tipo 1. Consideramos, assim, que a ultra-sonografia do pâncreas constitui metodologia auxiliar na classificação de diabéticos entre os tipo 1 e 2, sendo menos eficaz quando os últimos não são obesos.

  19. A ultra-sonografia do pâncreas é eficaz em diagnosticar o diabete melito tipo 1 e tipo 2?

    Directory of Open Access Journals (Sweden)

    Walkyria de Paula Pimenta

    2002-07-01

    Full Text Available Este trabalho foi realizado para verificar se a ultra-sonografia do pâncreas oferece dados auxiliares na classificação de diabéticos adultos dos tipos 1 e 2. O tamanho e a ecogenicidade do pâncreas foram determinados pela ultra-sonografia em 81 diabéticos, sendo 20 do tipo 1 e 61 do tipo 2 (53 obesos e oito não-obesos. Os pacientes tipo 2 obesos diferiram dos demais por apresentarem área total e diâmetro ântero-posterior do corpo do pâncreas significativamente maiores. Quanto à ecogenicidade pancreática, esta estava aumentada com maior freqüência nos diabéticos tipo 2 obesos que nos diabéticos tipo 1. Consideramos, assim, que a ultra-sonografia do pâncreas constitui metodologia auxiliar na classificação de diabéticos entre os tipo 1 e 2, sendo menos eficaz quando os últimos não são obesos.

  20. Intoxicação experimental de bovinos com toxina botulínica tipo D

    Directory of Open Access Journals (Sweden)

    Colbachini L.

    1999-01-01

    Full Text Available Realizou-se uma intoxicação experimental em bovinos, pela administração oral, com diferentes doses de toxina botulínica tipo D. O objetivo foi determinar o tempo de permanência da toxina no sangue circulante de bovinos, pela detecção da toxina no soro mediante bioensaio em camundongos, e de verificar a presença da toxina no fígado, no baço, nos rins e no coração, e no conteúdo ruminal de bovinos que morreram e/ou foram sacrificados. Utilizaram-se 12 bovinos, mestiços, divididos em quatro grupos de três animais cada. Os grupos I, II e III receberam 200DL50/ml, 21.300DL50/ml e 63.200DL50/ml de toxina botulínica, respectivamente, e o grupo IV manteve-se como controle. A toxina foi detectada principalmente no soro dos bovinos pertencentes aos grupos II e III que receberam altas doses do inóculo tóxico, nos quais a toxina permaneceu por um período de um a sete dias após o aparecimento dos primeiros sinais clínicos da doença. A toxina não foi detectada no fígado, no baço, nos rins e no coração, mas o foi no conteúdo ruminal de um bovino do grupo II. A toxina botulínica foi mais facilmente detectada no soro do que nos órgãos dos bovinos, sendo encontrada principalmente quando o animal ingeriu muita toxina, durante a fase inicial da doença e por um período de sete dias.

  1. Comparison of Russian and IVS intensive series

    Science.gov (United States)

    Kurdubov, S. L.

    2013-08-01

    The article presents results of first comparison the Russian National UT1-UTC estimation program Ru-U and IVS-intensive international campaign. It is shown that the Ru-U sessions are performing with good accuracy and results can be included into international VLBI data processing scheme. Comparison of different distributions shows that the problem of correlation lack between single delay formal errors and UT1 estimations are presented both in Ru-U and IVS-intensive series.

  2. Central line infections - hospitals

    Science.gov (United States)

    ... infection; Central venous catheter - infection; CVC - infection; Central venous device - infection; Infection control - central line infection; Nosocomial infection - central line infection; Hospital acquired ...

  3. Biopirataria: reflexões sobre um tipo penal

    OpenAIRE

    Ivanira Pancheri

    2013-01-01

    O foco do presente Doutorado cinge-se ao tema Biopirataria reflexionando sob a criação de um respectivo tipo penal. Não obstante a ausência de uma conceituação jurídica uníssona sobre Biopirataria parte-se da concepção primordial de um acesso irregular ao Patrimônio Genético e ainda, aos Conhecimentos Tradicionais associados. Não se olvide todavia que, ao lado destes dois grandes nortes, comportamentos outros igualmente conformam a problemática, demandando coibição, ad exemplum, a não reparti...

  4. Terapêutica da diabetes mellitus tipo 1

    OpenAIRE

    Antunes, Ana Luisa Lopes

    2009-01-01

    Introdução: Diabetes Mellitus (DM) é uma doença metabólica de etiologia múltipla caracterizada por hiperglicemia crónica com distúrbios no metabolismo dos hidratos de carbono, lípidos e proteínas, por deficiências na secreção e/ou acção da insulina. A descoberta da insulina em 1921, foi um grande marco na sua terapêutica, aumentando a esperança e qualidade de vida dos doentes, nomeadamente na DM tipo 1. Tornou-se um fármaco salvador de vidas (life saving). A primeira a ser comercializad...

  5. COMPORTAMENTO HIGROSCÓPICO DA LINGUIÇA TIPO CALABRESA

    OpenAIRE

    Piaia, Julio Cesar Zanchet; Quadri,Marintho Bastos; Bolzan, Ariovaldo

    2012-01-01

    O presente trabalho teve como objetivo a obtenção de isotermas de dessorção de umidade da linguiça tipo calabresa cozida e defumada. As isotermas foram obtidas em três temperaturas (20, 30, e 40 °C) em condições de dessorção, através do método gravimétrico estático, com soluções de ácido sulfúrico. Os dados experimentais foram ajustados a quatro modelos matemáticos da literatura (Henderson, Oswin, GAB e BET modificado) e determinou-se o valor do conteúdo de umidade da monocamada. O produto ap...

  6. Cirurgia metabólica: cura para diabete tipo 2

    OpenAIRE

    Zeve,Jorge Luiz de Mattos; Tomaz, Carlos Alberto Bezerra

    2011-01-01

    INTRODUÇÃO: O diabete melito tipo 2 é doença metabólica caracterizada por hiperglicemia crônica que está associada com dano e insuficiência de vários órgãos. A evolução da doença é a causa mais comum de cegueira, amputações e insuficiência renal em adultos no ocidente, além de aumentar a incidência de infarto agudo do miocárdio e acidente vascular cerebral, com maior mortalidade dos pacientes. A associação dele com obesidade é relevante. Os pacientes obesos diabéticos quando submetidos ao tra...

  7. formales o categorías tipo interfase?

    Directory of Open Access Journals (Sweden)

    Julio Alfonso Piña López

    2011-01-01

    Full Text Available Se analiza la relación entre los fenómenos básicos y los fenómenos del desarrollo y la personalidad, en términos de si los primeros deberían concebirse como condición de existencia necesaria y suficiente de los segundos, y, a su vez, si los unos y los otros lo son de los últimos. Se concluye que dependiendo de cómo se plantee dicha relación, es que eventualmente tendrá sentido la construcción de teorías formales sobre el desarrollo y la personalidad, o bien caracterizar ambos fenómenos como categorías tipo interfase con fines de predicción.

  8. Tipos de socialización y desesperanza aprendida

    Directory of Open Access Journals (Sweden)

    Sandro Macassi

    1988-12-01

    Full Text Available Las nociones de alienación, falta de poder y desesperanza aprendida son revisadas. Sesenta obreros de una empresa limeña fueron evaluados en términos del tipo de socialización dominante (SD y desesperanza aprendida (DA en sus tres áreas: falta de motivación, falta de control y expectativas de no-control en el futuro. Las escalas SD y DA resultaron consistentes. El análisis de regresión múltiple con las variables grado de división del trabajo, el grado de instrucción y –en migrantes- edad de arribo y permanencia en la capital, evidenció que el único predictor de DA es el grado de instrucción, correlacionándose negativamente. Los resultados se discuten a la luz de la realidad peruana.

  9. Una propuesta de tipo investigativo - interventivo para construir resiliencia

    Directory of Open Access Journals (Sweden)

    Sandra Liliana Aya Angarita

    2012-01-01

    Full Text Available Este artículo continúa con las reflexiones planteadas en la tesis magistral “Procesos de construcciónnarrativa que organizan experiencias resilientes enfamilias en situación de desplazamiento, en la interaccióninstitución familia” (articulada a la Maestríade Psicología Clínica y de Familia de la Universidad Santo Tomás, en las que se pretende comprender losprocesos de construcción narrativa y el interventivo busca movilizar dichos procesos hacia la emergenciade experiencias resilientes. El texto muestra algunos resultados de la intención interventiva, definiendola resiliencia desde diversas perspectivas, para luego conectar dichos significados con los procesos de construcción narrativa. Finalmente se proponenideas acerca de cómo en un escenario conversacional de tipo reflexivo es posible movilizar procesos haciala construcción de experiencias resilientes.

  10. Estudo clinico da epilepsia catamenial: tipos clinicos das crises epilepticas

    Directory of Open Access Journals (Sweden)

    Arthur Oscar Schelp

    1983-06-01

    Full Text Available Foram atendidas 431 pacientes epilépticas com idades acima de 10 anos, no período de fevereiro a julho de 1981 no ambulatório de neurologia do H.C.F.M.R.P. Destas, foram selecionadas 119 pacientes com idade de 13 a 45 anos e/ou fluxo menstrual periódico e pelo menos uma crise epiléptica ao mês. As pacientes foram separadas em dois grupos, o primeiro constituído de 36 pacientes com diagnóstico de epilepsia catamenial e o segundo com 83 pacientes que apresentavam epilepsia não catamenial. Determinamos um coeficiente de prevalência de 105,9/1000 para a epilepsia catamenial. Classificamos os tipos clínicos de crises epilépticas ocorridas em pacientes com epilepsia catamenial e comparamos com as ocorridas em pacientes na menacme.

  11. Observational properties of decameter type IV bursts

    Science.gov (United States)

    Melnik, Valentin; Brazhenko, Anatoly; Rucker, Helmut; Konovalenko, Alexander; Briand, Carine; Dorovskyy, Vladimir; Zarka, Philippe; Frantzusenko, Anatoly; Panchenko, Michael; Poedts, Stefan; Zaqarashvili, Teimuraz; Shergelashvili, Bidzina

    2013-04-01

    Oscillations of decameter type IV bursts were registered during observations of solar radio emission by UTR-2, URAN-2 and NDA in 2011-2012. Large majority of these bursts were accompanied by coronal mass ejections (CMEs), which were observed by SOHO and STEREO in the visible light. Only in some cases decameter type IV bursts were not associated with CMEs. The largest periods of oscillations P were some tens of minutes. There were some modes of long periods of oscillations simultaneously. Periods of oscillations in flux and in polarization profiles were close. Detailed properties of oscillations at different frequencies were analyzed on the example of two type IV bursts. One of them was observed on April 7, 2011 when a CME happened. Another one (August 1, 2011) was registered without any CME. The 7 April type IV burst had two periods in the frames 75-85 and 35-85 minutes. Interesting feature of these oscillations is decreasing periods with time. The observed decreasing rates dP/dt equaled 0.03-0.07. Concerning type IV burst observed on August 1, 2011 the period of its oscillations increases from 17 min. at 30 MHz to 44 min. at 10 MHz. Connection of type IV burst oscillations with oscillations of magnetic arches and CMEs at corresponding altitudes are discussed. The work is fulfilled in the frame of FP7 project "SOLSPANET".

  12. Todo tipo de relacionamento consumidor-marca é eficiente?

    Directory of Open Access Journals (Sweden)

    Eliane Cristine Francisco-Maffezzolli

    2014-03-01

    Full Text Available O objetivo neste estudo foi investigar a existência de diferentes perfis de relacionamento consumidor-marca e sua respectiva eficiência na relação comercial. Três construtos da teoria de relacionamento com marcas foram avaliados: autoconexão, intimidade e interdependência com a marca. Foi realizado um survey com 441 casos. Os dados foram analisados por técnicas de cluster, fatorial e ANOVA. Três diferentes perfis foram encontrados: o relacionamento por inércia (RI, o qual sugere uma relação superficial e com menor poder de diferenciação sobre a marca; o relacionamento moderado (RM, o qual registrou avaliações intermediárias em todas as variáveis; o relacionamento verdadeiro (RV, o qual demonstra maior proximidade e conexão com a marca. Para verificar a eficiência desses tipos, foram avaliados os índices de satisfação, confiança, comprometimento e lealdade. Consumidores do tipo RI tendem a trocar de marca tão logo percebam vantagens maiores em outros concorrentes. Já os RM demonstram certa tendência de atitudes positivas em relação à marca, dependendo de seu contexto e oferta. O grupo RV demonstra maior tendência à continuidade do relacionamento. Do ponto de vista gerencial, perceber diferentes intensidades de relacionamento permite reconhecer que nem todo relacionamento é eficiente.

  13. Tipos (Guía de programación de C#)

    OpenAIRE

    MSDN, Microsoft

    2015-01-01

    C# es un lenguaje fuertemente tipado. Todas las variables y constantes tienen un tipo, al igual que toda expresión que da como resultado un valor.Cada firma de método especifica un tipo para cada parámetro de entrada y para el valor devuelto.La biblioteca de clases .NET Framework define un conjunto de tipos numéricos integrados y tipos más complejos que representan una amplia variedad de construcciones lógicas, como el sistema de archivos, conexiones de red, colecciones y matrices de objetos ...

  14. Axis IV--psychosocial and environmental problems--in the DSM-IV.

    Science.gov (United States)

    Ramirez, A; Ekselius, L; Ramklint, M

    2013-11-01

    The aim of this study was to further explore the properties of axis IV in the Diagnostic and statistical manual of mental disorders, 4th edition (DSM-IV). In a naturalistic cross-sectional design, a group (n = 163) of young (18-25 years old) Swedish psychiatric outpatients was assessed according to DSM-IV. Psychosocial and environmental problems/axis IV were evaluated through structured interviewing by a social worker and by self-assessment on a questionnaire. Reliability between professional assessment and self-assessment of axis IV was examined. Concurrent validity of axis IV was also examined. Reliability between professional and self-assessed axis IV was fair to almost perfect, 0.31-0.83, according to prevalence and bias-adjusted kappa. Categories of psychosocial stress and environmental problems were related to the presence of axis I disorders, co-morbidity, personality disorders and decreasing Global Assessment of Functioning (GAF) values. The revised axis IV according to DSM-IV seems to have concurrent validity, but is still hampered by limited reliability.

  15. Central Solenoid

    CERN Multimedia

    2002-01-01

    The Central Solenoid (CS) is a single layer coil wound internally in a supporting cylinder housed in the cryostat of the Liquid Argon Calorimeter. It was successfully tested at Toshiba in December 2000 and was delivered to CERN in September 2001 ready for integration in the LAr Calorimeter in 2003. An intermediate test of the chimney and proximity cryogenics was successfully performed in June 2002.

  16. EMISSÕES SOLARES TIPO-U E TIPO-J DECIMÉTRICAS REGISTRADAS PELO BRAZILIAN SOLAR SPECTROSCOPE (BSS

    Directory of Open Access Journals (Sweden)

    José Augusto S. S. Dutra

    2013-09-01

    Full Text Available Neste trabalho são apresentados os resultados da análise de cinco emissões solares tipo-U e tipo-J registradas pelo rádio espectrógrafo “Brazilian Solar Spectroscope” (BSS em frequências decimétricas (1,0 – 2,5 GHz, entre junho de 2000 e outubro de 2001. As características espectro-temporais das emissões foram medidas a partir dos espectros dinâmicos. Considerando a emissão de plasma no segundo harmônico, foram inferidos os seguintes parâmetros da fonte emissora: densidade de fluxo inferior a 20 – 80 u.f.s.; comprimento dos arcos magnéticos da ordem de (0,3 – 5,1 ´ 1010 cm; velocidade dos feixes de elétrons de (0,47 – 1,16 ´ 105 km/s; densidade máxima dos feixes de elétrons de (0,56 - 1,95 ´ 105 cm-3; máximo de (2,53 – 7,37 ´ 1031 elétrons no feixe; temperatura do topo dos arcos magnéticos de (2,5 – 15,5 ´ 106 K; e limite inferior para a intensidade do campo magnético na região do plasma confinado de 7 – 22 G. Os resultados são comparados com determinações publicadas na literatura.

  17. Europa central

    Directory of Open Access Journals (Sweden)

    Karel BARTOSEK

    2010-02-01

    Full Text Available La investigación francesa continúa interesándose por Europa Central. Desde luego, hay límites a este interés en el ambiente general de mi nueva patria: en la ignorancia, producto del largo desinterés de Francia por este espacio después de la Segunda Guerra Mundial, y en el comportamiento y la reflexión de la clase política y de los medios de comunicación (una anécdota para ilustrar este ambiente: durante la preparación de nuestro coloquio «Refugiados e inmigrantes de Europa Central en el movimiento antifascista y la Resistencia en Francia, 1933-1945», celebrado en París en octubre de 1986, el problema de la definición fue planteado concreta y «prácticamente». ¡Y hubo entonces un historiador eminente, para quién Alemania no formaría parte de Europa Central!.

  18. E1B 55k-independent dissociation of the DNA ligase IV/XRCC4 complex by E4 34k during adenovirus infection

    OpenAIRE

    2008-01-01

    The ligase IV/XRCC4 complex plays a central role in DNA double-strand break repair by non-homologous end joining (NHEJ). During adenovirus infection, NHEJ is inhibited by viral proteins E4 34k and E1B 55k, which redirect the Cul5/Rbx1/Elongin BC ubiquitin E3 ligase to polyubiquitinate and promote degradation of ligase IV. In cells infected with E1B 55k-deficient adenovirus, ligase IV could not be found in XRCC4-containing complexes and was observed in a novel ligase IV/E4 34k/Cul5/Elongin BC ...

  19. Confirmatory Factor Analysis of the WAIS-IV and WMS-IV in Older Adults

    Science.gov (United States)

    Miller, Delyana I.; Davidson, Patrick S. R.; Schindler, Dwayne; Messier, Claude

    2013-01-01

    New editions of the Wechsler Adult Intelligence and Memory scales are now available. Yet, given the significant changes in these new releases and the skepticism that has met them, independent evidence on their psychometric properties is much needed but currently lacking. We administered the WAIS-IV and the Older Adult version of the WMS-IV to 145…

  20. On the stabilization of niobium(V) solutions by zirconium(IV) and hafnium(IV)

    DEFF Research Database (Denmark)

    Sørensen, E.; Bjerre, A.B.

    1992-01-01

    Niobium cannot be separated from zirconium or hafnium when these elements occur together in solution with common anions such as chloride and sulphate. This is ascribed to the co-polymerization of niobium(V) and the hydrolysed ionic species of zirconium(IV) and hafnium(IV) to form colloidal...

  1. Reducing bloodstream infection with a chlorhexidine gel IV dressing.

    Science.gov (United States)

    Jeanes, Annette; Bitmead, James

    The use of vascular access devices (VAD) is common in healthcare provision but there is a significant risk of acquiring an infection. Central venous catheters (CVC) are associated with the highest risk of intravenous catheter-related bloodstream infection (CRBSI). 3M™ Tegaderm™ CHG IV dressing is a semi-permeable transparent adhesive dressing with an integrated gel pad containing chlorhexidine gluconate 2%. This product was reviewed by the National Institute for Health and Care Excellence (NICE) in 2015, recommending that Tegaderm CHG could be used for CVC and arterial line dressings in high-dependency and intensive-care settings. This article discusses issues around CRBSI, interventions to reduce the risk of CRBSI, and the use of Tegaderm CHG dressing.

  2. Thorium nanochemistry: the solution structure of the Th(IV)-hydroxo pentamer

    Energy Technology Data Exchange (ETDEWEB)

    Walther, Clemens; Rothe, Jörg; Schimmelpfennig, Bernd; Fuss, Markus [Karlsruher

    2012-10-10

    Tetravalent thorium exhibits a strong tendency towards hydrolysis and subsequent polymerization. Polymeric species play a crucial role in understanding thorium solution chemistry, since their presence causes apparent solubility several orders of magnitude higher than predicted by thermodynamic data bases. Although electrospray mass spectrometry (ESI MS) identifies Th(IV) dimers and pentamers unequivocally as dominant species close to the solubility limit, the molecular structure of Th5(OH)y polymers was hitherto unknown. In the present study, X-ray absorption fine structure (XAFS) spectroscopy, high energy X-ray scattering (HEXS) measurements, and quantum chemical calculations are combined to solve the pentamer structure. The most favourable structure is represented by two Th(IV) dimers linked by a central Th(IV) cation through hydroxide bridges.

  3. Thorium nanochemistry: the solution structure of the Th(IV)-hydroxo pentamer.

    Science.gov (United States)

    Walther, Clemens; Rothe, Jörg; Schimmelpfennig, Bernd; Fuss, Markus

    2012-08-28

    Tetravalent thorium exhibits a strong tendency towards hydrolysis and subsequent polymerization. Polymeric species play a crucial role in understanding thorium solution chemistry, since their presence causes apparent solubility several orders of magnitude higher than predicted by thermodynamic data bases. Although electrospray mass spectrometry (ESI MS) identifies Th(IV) dimers and pentamers unequivocally as dominant species close to the solubility limit, the molecular structure of Th(5)(OH)(y) polymers was hitherto unknown. In the present study, X-ray absorption fine structure (XAFS) spectroscopy, high energy X-ray scattering (HEXS) measurements, and quantum chemical calculations are combined to solve the pentamer structure. The most favourable structure is represented by two Th(IV) dimers linked by a central Th(IV) cation through hydroxide bridges.

  4. Central pain.

    Science.gov (United States)

    Singh, Supreet

    2014-12-01

    Questions from patients about pain conditions and analgesic pharmacotherapy and responses from authors are presented to help educate patients and make them more effective self-advocates. The topic addressed in this issue is central pain, a neuropathic pain syndrome caused by a lesion in the brain or spinal cord that sensitizes one's perception of pain. It is a debilitating condition caused by various diseases such as multiple sclerosis, strokes, spinal cord injuries, or brain tumors. Varied symptoms and the use of pharmacological medicines and nonpharmacological therapies will be addressed.

  5. central t

    Directory of Open Access Journals (Sweden)

    Manuel R. Piña Monarrez

    2007-01-01

    Full Text Available Dado que la Regresión Ridge (RR, es una estimación sesgada que parte de la solución de la regresión de Mínimos Cuadrados (MC, es vital establecer las condiciones para las que la distribución central t de Student que se utiliza en la prueba de hipótesis en MC, sea también aplicable a la regresión RR. La prueba de este importante resultado se presenta en este artículo.

  6. Seafloor earthquake measurement system, SEMS IV

    Energy Technology Data Exchange (ETDEWEB)

    Platzbecker, M.R.; Ehasz, J.P.; Franco, R.J.

    1997-07-01

    Staff of the Telemetry Technology Development Department (2664) have, in support of the U.S. Interior Department Mineral Management Services (MMS), developed and deployed the Seafloor Earthquake Measurement System IV (SEMS IV). The result of this development project is a series of three fully operational seafloor seismic monitor systems located at offshore platforms: Eureka, Grace, and Irene. The instrument probes are embedded from three to seven feet into the seafloor and hardwired to seismic data recorders installed top side at the offshore platforms. The probes and underwater cables were designed to survive the seafloor environment with an operation life of five years. The units have been operational for two years and have produced recordings of several minor earthquakes in that time. Sandia Labs will transfer operation of SEMS IV to MMS contractors in the coming months. 29 figs., 25 tabs.

  7. The Berkeley SETI program - SERENDIP IV instrumentation

    Science.gov (United States)

    Werthimer, Dan; Bowyer, Stuart; Ng, David; Donnelly, Charles; Cobb, Jeff; Lampton, Michael; Airieau, Sabine

    1997-01-01

    We discuss the hardware design of SERENDIP IV, which will be deployed in early 1997 for a 21-cm sky survey at the National Astronomy and Ionospheric Center's 305-m radio telescope in Arecibo, Puerto Rico. SERENDIP IV is a 167 million channel spectrum analyzer, covering a 100-Mhz bandwidth, with 0.6-Hz resolution and a 1.7-s integration time. SERENDIP IV's modular design incorporates a bank of digital mixers and filters to separate the 100 MHz band into 40 2.5 MHz subbands. Each 2.5 MHz subband is further broken down into 0.6 Hz bins by means of a four million point fast Fourier transform. The resulting power spectra are analyzed by 40 high-speed processors. Narrowband signals having power significantly above background noise levels are recorded along with telescope coordinates, time, and frequency. The data are sent in real time to Berkeley for analysis.

  8. Oxochloroalkoxide of the Cerium (IV and Titanium (IV as oxides precursor

    Directory of Open Access Journals (Sweden)

    Machado Luiz Carlos

    2002-01-01

    Full Text Available The Cerium (IV and Titanium (IV oxides mixture (CeO2-3TiO2 was prepared by thermal treatment of the oxochloroisopropoxide of Cerium (IV and Titanium (IV. The chemical route utilizing the Cerium (III chloride alcoholic complex and Titanium (IV isopropoxide is presented. The compound Ce5Ti15Cl16O30 (iOPr4(OH-Et15 was characterized by elemental analysis, FTIR and TG/DTG. The X-ray diffraction patterns of the oxides resulting from the thermal decomposition of the precursor at 1000 degreesC for 36 h indicated the formation of cubic cerianite (a = 5.417Å and tetragonal rutile (a = 4.592Å and (c = 2.962 Å, with apparent crystallite sizes around 38 and 55nm, respectively.

  9. y Banca Central

    Directory of Open Access Journals (Sweden)

    Ángel García Banchs

    2008-01-01

    Full Text Available Las teorías monetarias modernas, ortodoxas y heterodoxas, han pasado por alto el hecho de que posterior a la Segunda Guerra Mundial el mundo quedó dividido entre economías emisoras y receptoras de reservas, pasando el sistema monetario internacional desde entonces a ser completamente asimétrico. De allí que, desde el punto de vista teórico, señalemos la necesidad de tomar en cuenta si las economías emiten o no una moneda de reserva internacional, pues ello explicaría la existencia de diversas prácticas monetarias a nivel mundial. Este trabajo propone, y calcula, indicadores basados en datos provenientes de los balances de activos y pasivos de quince bancos centrales pertenecientes a Norteamérica, Suramérica, Europa y Asia. Los hallazgos con respecto a las diversas estructuras de activos y pasivos confirman la hipótesis acerca de la presencia de tales asimetrías. Se infiere en consecuencia que la política monetaria es menos flexible pero más influyente en las economías receptoras de reservas, y a la vez más flexible pero menos influyente en las economías emisoras. En pocas palabras, la exogeneidad de la tasa de interés de corto plazo es más débil en el caso de las economías receptoras de reservas las cuales se ven obligadas a acumular divisas y a procurar la estabilidad del tipo de cambio, debido a que sus monedas locales no son aceptadas en el exterior. Así, aunque la oferta crediticia es endógena en esas economías, las mismas no han sido capaces de librarse aún de la necesidad de mantener reservas monetarias en divisas extranjeras

  10. Demencia tipo Alzheimer, deterioro cognitivo y toma de decisiones

    Directory of Open Access Journals (Sweden)

    Aurora Moreno

    2011-04-01

    Full Text Available El objetivo de este trabajo es el de conocer cómo es la toma de decisiones en la Demencia Tipo Alzheimer (DTA en situaciones de incertidumbre, si se manifiesta la tendencia al riesgo o no, y la relación que guarda la ejecución con el status cognitivo en cada una de las áreas evaluadas por los test de cribado del deterioro cognitivo propios de las demencias. Participaron 10 pacientes con DTA, y comparados con 10 sujetos controles. Se utilizó la Prueba Cartas (basada en la Iowa Gambling Task, donde los sujetos deben elegir entre varias opciones que entrañan más o menos riesgo, y una batería de cribado del deterioro cognitivo. Los resultados reflejaron que los sujetos con DTA en etapas iniciales presentan cierta tendencia al riesgo en las decisiones que toman y no desarrollan patrones estratégicos de elección. Parece que el deterioro cognitivo y el grado de afectación en las distintas áreas se relaciona con la forma en que toman decisiones.

  11. Polityka religijna Ptolemeusza IV Filopatora : wybrane aspekty

    OpenAIRE

    Grabowski, Tomasz

    2014-01-01

    Religion was very highly placed in the politics and propaganda of the Ptolemaic dynasty. Ptolemy IV Philopator belonged to the kings of Egypt who were particularly active in this field. The person of Ptolemy I Soter, who was the founder of the dynasty, was of considerable importance in his policy. Among many other things, Ptolemy IV established his eponymous cult in Ptolemais. He also invested the dynastic cult with its final form by incorporating into it the cult of Theoi Soters (Ptolemy I a...

  12. Tamponamento das lesões hepáticas transfixantes com colágeno tipo I

    Directory of Open Access Journals (Sweden)

    Mantovani Mario

    1998-01-01

    Full Text Available Nos últimos seis anos temos utilizado o balão de SANGESTAKEN-BLACKMORE para o tamponamento de lesões transfixantes hepáticas. Para substituir este corpo estranho, consideramos o uso de colágeno tipo I produzido na UNICAMP, o qual pode ser injetado e moldado ocupando toda a área lesada e o trajeto anfractuoso ou irregular. Desta forma, pode-se conseguir um tamponamento completo, coibindo a hemorragia e sustando a perda de bile. O colágeno será posteriormente reabsorvido não funcionando como corpo estranho. Vinte cães foram submetidos a lesão transfixante na região central do fígado, procurando simular uma lesão produzida por um projétil de arma de fogo. Quatro destes animais, não receberam tratamento e foram a óbito por choque hemorrágico. Em todos os outros 16 animais, aplicou-se o colágeno tipo I em toda a extensão do túnel formado pela lesão, através de injeção do material. Foram realizadas avaliações clínicas no pós-operatório, sendo os cães sacrificados, em grupo de quatro, aos quatro, sete, 15 e 30 dias de pós-operatório. O estudo macroscópico e o microscópico, tanto à microscopia óptica quanto à de polarização, revelou uma formação cicatricial homogênea, com regeneração hepática intensa, precoce e organizada, a partir do 7º dia de pós-operatório. Conclui-se que a aplicação do colágeno tipo I, nestes tipos de ferimentos, são de aplicação simples e segura.

  13. GROWING MAGNETIC FIELDS IN CENTRAL COMPACT OBJECTS

    Directory of Open Access Journals (Sweden)

    C. G. Bernal

    2011-01-01

    Full Text Available Estudiamos el efecto de un modelo de crecimiento del campo magnético en los llamados Objetos Compactos Centrales (OCCs. Tal evolución del campo magnético no es una idea nueva (Blandford, Applegate, & Hernquist 1983 pero sus implicaciones evolutivas no han sido estudiadas completamente (Michel 1994. Discutimos las nuevas clases de estrellas de neutrones, las cuales se presentan en cinco tipos reconocidos en los últimos diez años. Comentamos la posibilidad de que un pulsar magnetizado, débilmente rotante, pueda haberse formado en SN1987A.

  14. Le Tumulus - Cromlech de Millagate IV (Compte rendu de fouilles 1986.

    Directory of Open Access Journals (Sweden)

    Jacques Blot

    1988-01-01

    Full Text Available El túmulo - cromlech de Millagate IV, excavado en 1986, mide 12 m. de diámetro y 0,50 m. de alto. Se aprecia una corona externa de grandes piedras, que en su cara interna contiene un pequeño murete de piedras dispuestas en 3 o 4 capas. En el centro, a 1 m. de profundidad, una hermosa cista de 1,10 m. x 0,50 m. contenía carbón vegetal y un importante depósito de restos óseos humanos calcinados: los restos de un único individuo, robusto, adulto, de sexo masculino; sin ningún ajuar. Es la primera vez que se encuentra un depósito de huesos semejante en un círculo de piedras del País Vasco, lo que confirma claramente la finalidad funeraria de este tipo de monumentos.

  15. Nonpreference of whitefly for oviposition in tomato genotypes Não-preferência para oviposição de mosca-branca por genótipos de tomateiro

    Directory of Open Access Journals (Sweden)

    Luciana Cláudia Toscano

    2002-12-01

    Full Text Available The silverleaf whitefly is one of most important pests of tomato (Lycopersicon spp.. The use of host plant resistance to control this insect is an interesting, potentially useful technique, but in demand of more research. The objectives of this work were to evaluate the oviposition non-preference of Bemisia tabaci (Gennadius, 1889 biotype B for different tomato plant genotypes, evaluating the correlation between oviposition preference and pubescence in the genotypes, and analyzing the abaxial and adaxial surfaces of Lycopersicon pennellii leaflets under the scanning electron microscope. Four wild tomato genotypes, LA 716 (L. pennellii; PI 127826 and PI 127827 (L. hirsutum; PI 134417 (L. hirsutum f. glabratum, and two commercial genotypes, Santa Clara and Bruna VFN hybrid (L. esculentum were evaluated for number of eggs cm-2 in free and no-choice oviposition tests, using randomized block design and completely randomized design, respectively. The number of trichome was measured in 4 mm² and coefficients of correlation between number of trichomes and number of eggs were calculated. The wild genotypes LA 716 and PI 134417 were less preferred showing oviposition nonpreference resistance type in both tests. The Bruna VFN and Santa Clara were more preferred in free-choice test, while wild genotypes PI 127826 and PI 127827 were more preferred in no-choice test. L. pennellii leaflets presented glandular trichomes type IV in both surfaces. Santa Clara genotype presented higher density of trichomes, and B. tabaci biotype B presented higher preference to oviposition.A mosca-branca Bemisia tabaci (Gennadius, 1889 biótipo B é atualmente uma das principais pragas do tomateiro (Lycopersicon spp.. O uso de plantas resistentes para o controle deste inseto apresenta-se interessante, com grande potencial para Manejo Integrado de Pragas. Este trabalho teve por objetivos verificar a não-preferência para oviposição de B. tabaci biótipo B em genótipos de

  16. Dipeptidyl peptidase-IV (DPP-IV inhibitory activity of parotid exudate of Bufo melanostictus

    Directory of Open Access Journals (Sweden)

    Allenki Venkatesham

    2009-01-01

    Full Text Available Type 2 diabetes arises as a result of β-cell failure combined with concomitant insulin resistance. Glucagon-like peptide-1 is a gastrointestinal hormone that is released postprandially from the L cells of the gut and exerts a glucose- dependent and direct insulinotropic effect on the pancreatic β cell. Which activate adenylate cyclase and enhances insulin secretion. GLP-1 is rapidly degraded by DPP-IV to GLP-1(9-37 amide following release from gut L cells. GLP-1 directly enhances glucose-dependent insulin secretion via an increase in β-cell cAMP. Dipeptidyl peptidase IV (DPP-IV is a plasma membrane glycoprotein ectopeptidase. In mammals, DPP-IV was widely expressed on the surface of endothelial and epithelial cells and highest levels in humans have been reported to occur in the intestine, bone marrow and kidney. Inhibiting DPP-IV reduces its rapid degradation of GLP-1, increasing circulating levels of the active hormone in vivo and prolonging its beneficial effects. The IC 50 value of parotid exudate was found to be 9.4 μg/ml. The maximum % inhibition (61.8 was showed at a concentration of 12μg/ml. Parotid exudate through inhibition of DPP-IV, improves glucose tolerance and enhances insulin secretion. DPP-IV inhibitors are a novel class of oral hypoglycemic agents with a potential to improve pancreatic beta cell function and the clinical course of type 2 diabetes.

  17. Tipo de parto: expectativas das mulheres Tipo de parto: expectativas de las mujeres Childbirth types: women's expectations

    Directory of Open Access Journals (Sweden)

    Sonia Maria Junqueira Vasconcellos de Oliveira

    2002-10-01

    Full Text Available Estudo descritivo e exploratório, realizado mediante entrevista com 221 puérperas que tiveram parto em maternidades públicas estaduais, localizadas no município de São Paulo. Teve como objetivos: 1. identificar o tipo de parto esperado pelas mulheres, considerando a via vaginal ou cesariana, e sua justificativa; 2. verificar a ocorrência do tipo de parto, segundo as expectativas dessas mulheres; 3. comparar a indicação médica da cesariana com o entendimento das mulheres sobre justificativa dessa intervenção. Os dados revelam que 74,7% tinham expectativa de que o parto fosse normal, e 25,3%, de que fosse cesárea. O parto normal, esperado por 165 entrevistadas, ocorreu em 66,1% dessas mulheres. A justificativa mais citada pelas mulheres para esperar o parto normal foi a recuperação pós-parto mais rápida e, para a cesárea, ter tido cesárea anterior. As justificativas apresentadas por 61 mulheres para a realização da cesariana não era coincidente com a indicação médica em 47,5% dos casos.Estudio descriptivo y exploratorio, realizado mediante entrevista con 221 puerperas que tuvieron el parto en maternidades públicas de en la ciudad de São Paulo. La investigación tuvo como objetivos: 1. identificar el tipo de parto esperado por las mujeres, considerando la vía vaginal o cesárea y su justificación; 2. verificar la ocurrencia del tipo de parto, según las expectativas de esas mujeres; 3. comparar la indicación médica da la cesárea con la comprensión de las mujeres sobre la justificación para esa intervención. Los datos muestran que 74,7% de las mujeres tenían la expectativa de que el parto fuese normal y 25,3% que fuese cesárea. El parto normal, esperado por 165 entrevistadas, ocurrió en 66,1% de estas mujeres. La justificativa más utilizada por las mujeres para esperar el parto normal fue la recuperación postparto más rápida y para la cesárea, haber tenido la cesárea anterior. La justificación presentada

  18. TFRC—IVS Flow Control Algorithm

    Institute of Scientific and Technical Information of China (English)

    HEKaijian; LINYaping; YANGAng

    2003-01-01

    This paper investigates the TCP (Trans-mission Control Protocol) friendliness of multicast video-conferencing systems. Through the analysis and simulation experiments it is shown that the slow response to network state changes and the fixed rate adjustment process lead to TCP unfriendliness in the bandwidth sharing. Therefore,this paper proposes a new TCP friendly flow control al-gorithm called TFRC-IVS flow control algorithm for the current best-effort Internet. TFRC-IVS (TCP-Friendly Rate Control--INRIA Videoconferencing System) algo-rithm utilizes TCP friendly control function derived from complex TCP model to calculate TCP friendly sending rate.Simulation results show that TFRC-IVS flow control algorithm improves the smoothness of transmission rates and converges quickly to the stable sending rate. In addi-tion, the TCP friendly control function in TFRC-IVS flow control algorithm ensures the TCP friendliness of video flows and fair bandwidth allocation with TCP flows, which the traditional static rate adjustment algorithm lacks.

  19. Bis(4-methylpiperidinium hexachloridostannate(IV

    Directory of Open Access Journals (Sweden)

    Madeleine Helliwell

    2008-04-01

    Full Text Available The crystal structure of the title compound, (C6H14N2[SnCl6], is built of 4-methylpiperidinium cations, occupying special positions on the mirror plane, and hexachloridostannate(IV anions on a special position of 2/m symmetry. The ions are linked via N—H...Cl hydrogen bonds into chains running along the b axis.

  20. Painlevé IV coherent states

    Energy Technology Data Exchange (ETDEWEB)

    Bermudez, David, E-mail: david.bermudez@weizmann.ac.il [Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100 (Israel); Departamento de Física, Cinvestav, A.P. 14-740, 07000 México D.F. (Mexico); Contreras-Astorga, Alonso, E-mail: aloncont@iun.edu [Department of Mathematics and Actuarial Science, Indiana University Northwest, 3400 Broadway, Gary IN 46408 (United States); Departamento de Física, Cinvestav, A.P. 14-740, 07000 México D.F. (Mexico); Fernández C, David J., E-mail: david@fis.cinvestav.mx [Departamento de Física, Cinvestav, A.P. 14-740, 07000 México D.F. (Mexico)

    2014-11-15

    A simple way to find solutions of the Painlevé IV equation is by identifying Hamiltonian systems with third-order differential ladder operators. Some of these systems can be obtained by applying supersymmetric quantum mechanics (SUSY QM) to the harmonic oscillator. In this work, we will construct families of coherent states for such subset of SUSY partner Hamiltonians which are connected with the Painlevé IV equation. First, these coherent states are built up as eigenstates of the annihilation operator, then as displaced versions of the extremal states, both involving the related third-order ladder operators, and finally as extremal states which are also displaced but now using the so called linearized ladder operators. To each SUSY partner Hamiltonian corresponds two families of coherent states: one inside the infinite subspace associated with the isospectral part of the spectrum and another one in the finite subspace generated by the states created through the SUSY technique. - Highlights: • We use SUSY QM to obtain Hamiltonians with third-order differential ladder operators. • We show that these systems are related with the Painlevé IV equation. • We apply different definitions of coherent states to these Hamiltonians using the third-order ladder operators and some linearized ones. • We construct families of coherent states for such systems, which we called Painlevé IV coherent states.

  1. Industrial Waste Landfill IV upgrade package

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-29

    The Y-12 Plant, K-25 Site, and ORNL are managed by DOE`s Operating Contractor (OC), Martin Marietta Energy Systems, Inc. (Energy Systems) for DOE. Operation associated with the facilities by the Operating Contractor and subcontractors, DOE contractors and the DOE Federal Building result in the generation of industrial solid wastes as well as construction/demolition wastes. Due to the waste streams mentioned, the Y-12 Industrial Waste Landfill IV (IWLF-IV) was developed for the disposal of solid industrial waste in accordance to Rule 1200-1-7, Regulations Governing Solid Waste Processing and Disposal in Tennessee. This revised operating document is a part of a request for modification to the existing Y-12 IWLF-IV to comply with revised regulation (Rule Chapters 1200-1-7-.01 through 1200-1-7-.08) in order to provide future disposal space for the ORR, Subcontractors, and the DOE Federal Building. This revised operating manual also reflects approved modifications that have been made over the years since the original landfill permit approval. The drawings referred to in this manual are included in Drawings section of the package. IWLF-IV is a Tennessee Department of Environmental and Conservation/Division of Solid Waste Management (TDEC/DSWM) Class 11 disposal unit.

  2. Rhabdoid choroid plexus carcinoma: a rare histological type Carcinoma de plexus coroides de tipo rabdoide: un tipo histológico raro

    Directory of Open Access Journals (Sweden)

    Martha Lilia Tena-Suck

    2007-09-01

    Full Text Available Primary central nervous system atypical teratoid/rhabdoid tumors mostly occur during early childhood and are almost invariably fatal. These tumors show similar histological and radiological features to primitive neuroectodermal tumor, meduloblastoma and choroid plexus carcinoma, but present different biological behaviors. We present the case of an 18 year-old man who presented headache, vomiting and ataxia. CT-scan and MRI revealed a posterior fossa tumor. A gross total resection was performed. An intraoperative study showed papillary-like tumors with large cells and mitotic features. Histological examination showed two different main growth patterns: solid sheets of undifferentiated polygonal cells with papillary features and rhabdoid cells. Immunohistochemically, these rhabdoid cells were positive for vimentin, epithelial membrane antigen, smooth-muscle actin, cytokeratin, S-100 protein, and glial fibrillary acidic protein. Electro-microscopically, the typical rhabdoid cells contained whorled bundles of intermediate filaments in their cytoplasm. A rhabdoid tumor is a clinicalpathological entity and emphasizes the necessity to distinguish this unique tumor from other pediatric central nervous system neoplasms. Cytopathological features, immunohistochemistry and electro-microscopy differential diagnoses are discussed.Los tumores de tipo rabdoide primarios en cualquier sitio son raros y en el sistema nervioso central son extremadamente raros y ocurren principalmente en niños, el tumor teratoide/rabdoide es el tumor más frecuente dentro de este grupo y de evolución clínica fatal. El tumor neuroectodermico primitivo, medulobalstoma y al carcinoma de plexos coroides son tumores generalmente muestran aspectos clínicos radiológicos e histológicos similares, con evolución diferente. Presentamos el caso de un hombre joven de 18 años que inició con cefalea vómitos y ataxia. La imagen de TC muestra tumor en fosa posterior. Se realizó resecci

  3. Gen IV Materials Handbook Implementation Plan

    Energy Technology Data Exchange (ETDEWEB)

    Rittenhouse, P.; Ren, W.

    2005-03-29

    A Gen IV Materials Handbook is being developed to provide an authoritative single source of highly qualified structural materials information and materials properties data for use in design and analyses of all Generation IV Reactor Systems. The Handbook will be responsive to the needs expressed by all of the principal government, national laboratory, and private company stakeholders of Gen IV Reactor Systems. The Gen IV Materials Handbook Implementation Plan provided here addresses the purpose, rationale, attributes, and benefits of the Handbook and will detail its content, format, quality assurance, applicability, and access. Structural materials, both metallic and ceramic, for all Gen IV reactor types currently supported by the Department of Energy (DOE) will be included in the Gen IV Materials Handbook. However, initial emphasis will be on materials for the Very High Temperature Reactor (VHTR). Descriptive information (e.g., chemical composition and applicable technical specifications and codes) will be provided for each material along with an extensive presentation of mechanical and physical property data including consideration of temperature, irradiation, environment, etc. effects on properties. Access to the Gen IV Materials Handbook will be internet-based with appropriate levels of control. Information and data in the Handbook will be configured to allow search by material classes, specific materials, specific information or property class, specific property, data parameters, and individual data points identified with materials parameters, test conditions, and data source. Details on all of these as well as proposed applicability and consideration of data quality classes are provided in the Implementation Plan. Website development for the Handbook is divided into six phases including (1) detailed product analysis and specification, (2) simulation and design, (3) implementation and testing, (4) product release, (5) project/product evaluation, and (6) product

  4. Remote Control Research in Central Africa

    OpenAIRE

    Trefon, Theodore; Cogels, Serge

    2009-01-01

    This article explains how a project being implemented in peri-urban central Africa is coordinated from an office in Brussels. After an overview that addresses the conceptual challenges of defining ‘peri-urban’ and the question of why these social spaces are important from a development perspective, the article outlines ‘remote control research’ step-by-step: (i) conceptualisation, (ii) identification and recruitment of local experts, (iii) selection of research sites, (iv) the process of form...

  5. Implantes inmediatos transalveolares tipo IMETI®. Reporte de un caso

    Directory of Open Access Journals (Sweden)

    Joyce Barrios Mejía

    2013-10-01

    Full Text Available ResumenHoy en día existen avances en el concepto de mantenimiento y regeneración ósea. Es bien conocido en el ámbito de la odontología que tras una exodoncia se produce una reabsorción del alveolo residual dentro del mismo proceso de cicatrización y remodelación gingival y ósea, pero para evitar estos inconvenientes se plantean los implantes inmediatos insertados en el mismo acto quirúrgico en el cual se extrae el diente a sustituir. Con respecto a los implantes diferidos, tienen precisamente la ventaja de disminuir la continua reabsorción ósea del alveolo postextracción, acortar el tiempo de tratamiento rehabilitador y evitar segundas cirugías de implantación. El objetivo de este artículo es caracterizar a través de un caso el éxito de esta técnica quirúrgica con la convencional utilizando los implantes tipo IMETI ®. (Duazary 2007; 1: 45 - 51AbstractNow a days exists an advance in the maintenance concept and bony regeneration. is very well-known that after an exodontic a reabsorption of the residual alveolus takes place inside the same scaring process and gingival remodeling and bony, to avoid these inconveniences, it is thought about the immediate implant inserted in the same surgical act in which the tooth to substitute is extracted. With regard the differed implants; they have the advantage of diminishing the continuous bony reabsorption of the alveolus post-extraction, to shorten the time of rehabilitative treatment and to avoid second implantation surgeries. The objective of the present case, is to characterize the success of this surgical technique with the conventional used the IMETI ® implants.Key Words: Extraction; Implant; Alveolus; IMETI ®

  6. O uso de politetrafluoroetileno expandido em tireoplastia tipo I

    Directory of Open Access Journals (Sweden)

    Mello-Filho Francisco Veríssimo de

    2003-01-01

    Full Text Available A paralisia unilateral de prega vocal (PUPV em abdução é uma alteração que produz grande desconforto ao paciente, principalmente pelos distúrbios fonatórios causados. Atualmente dispomos de uma variedade de métodos para seu tratamento. OBJETIVO: Verificar a eficiência, vantagens e desvantagens do uso da fita de politetrafluoretileno expandido (PTFE-e, na medialização de prega vocal (PV paralisada, em abdução. FORMA DE ESTUDO: Coorte Longitudinal. MATERIAL E MÉTODOS: Foram estudados quatro pacientes com diagnóstico clínico-laringoscópico de disfonia por PPVU, em abdução há pelo menos um ano. Os pacientes foram submetidos a avaliação fonoaudiológica e a tireoplastia tipo I para medialização da PV com fita de PTFE-e. Durante o seguimento pós-operatório procedeu-se videolaringoscopia, tomografia computadorizada e fonoterapia. RESULTADOS: Todos os pacientes estão satisfeitos com a qualidade vocal, apresentam medialização estável da PV com a fonocirurgia e bons resultados à avaliação fonoaudiológica. Um paciente apresentou extrusão intra-operatória da fita de PTFE-e, sendo feito um segundo procedimento, sem complicações, seis meses depois. CONCLUSÃO: Na opinião dos autores a fita de PTFE-e se presta com eficiência ao tratamento da PUPV, sem apresentar riscos importantes.

  7. Iværksætternes eksport og vækst

    DEFF Research Database (Denmark)

    Rind Christensen, Poul

    2009-01-01

    Artiklen belyser, hvordan den erhvervspolitiske interesse i stigende grad har samlet sig om to centrale spørgsmål, nemlig antallet af iværksættere i Danmark i forhold til andre lande og andelen af vækstiværksættere. Synspunktet er, at nok er vi i Danmark kommet på højde med andre lande, når det g...

  8. COMPOSTOS FENÓLICOS E ATIVIDADE ANTIOXIDANTE DE GENÓTIPOS DE CIRIGUELAS (SPONDIA PURPUREA L.

    Directory of Open Access Journals (Sweden)

    Quésia Jemima da SILVA

    2012-01-01

    Full Text Available Com o objetivo de determinar em frutos de 11 genótipos de cirigueleiras o teor de fenólicos totais e o potencial antioxidante foram preparados extratos hidrometanólicos e hidroacetônicos por extração sequencial. A ação antioxidante foi analisada utilizando dois ensaios: sequestro do radical DPPH● (1,1-difenil-2-picrilhidrazil e do radical ABTS+• (2,2’-azino-bis-(3-etilbenzotiazolina-6- acido sulfônico. O extrato obtido do genótipo IPA-10 apresentou maior teor de fenólicos totais (862,31mg EAG.g-1 de polpa, superando, estatisticamente, os extratos dos demais genótipos. Em relação ao percentual de sequestro do radical DPPH●, os extratos dos frutos de todos os genótipos apresentaram forte capacidade antioxidante, tendo em vista que os valores determinados foram superiores a 70%. O comportamento cinético dos extratos dos frutos dos genótipos IPA-2, IPA-3, IPA-4, IPA-5, IPA-6, IPA-7, IPA-8, IPA- 10 e IPA-11 foram classificados como rápidos (TEC50<5 minutos, no entanto, apenas o genótipo IPA-7 apresentou eficiência antirradical super alta. Com relação ao radical ABTS+• todos os genótipos apresentaram apreciável ação antioxidante com destaque para o extrato do genótipo IPA- 10 que demonstrou uma ação superior aos demais genótipos(6.633,87μM TEAC.g-1.

  9. Seleção de protótipos: combinando auto-geração de protótipos e mistura de gaussianas

    OpenAIRE

    de Santana Pereira, Cristiano

    2008-01-01

    Seleção de protótipos é uma técnica de aprendizagem de máquina cujo objetivo é a escolha ou produção de instâncias de dados que consigam a melhor representação para os dados do problema realçando as fronteiras de decisão e mantendo a separação entre as classes. A idéia é reduzir a quantidade de dados e ainda assim obter um conjunto de protótipos que minimize o erro de classificação. As estratégias baseadas em protótipos têm sido bastante utilizadas em aplicações reais nos mais diversos domíni...

  10. Estudos comparativos do ciclo de regeneração de diferentes tipos de silicoaluminofosfatos

    OpenAIRE

    Chellappa, Thiago

    2013-01-01

    Diferentes tipos de catalisadores heterogêneos do tipo silicoaluminofosfático, (SAPO-5, SAPO-11, SAPO-31, SAPO-34 e SAPO-41), peneiras moleculares com estrutura: AFI, AEL, ATO, CHA e AFO, respectivamente, foram sintetizados pelo método hidrotérmico. Utilizando-se de fontes como à alumina hidratada (pseudobohemita), ácido fosfórico, sílica gel, água e diferentes tipos de direcionadores estruturais orgânicos, tais como o: brometo de cetiltrimetilamônio (CTMABr), di-isopropilamina (DIPA), di-n-p...

  11. Déficit hídrico em tipos de crescimento da soja

    OpenAIRE

    Machado Júnior, Carlos Sebastião

    2015-01-01

    Estudos envolvendo o impacto do déficit hídrico na fisiologia da soja são abundantes, mas os que envolvam os tipos de crescimento determinado e indeterminado são escassos. Considerando que as respostas do tipo de crescimento para com o déficit hídrico podem ser de grande valor para o aperfeiçoamento de programas de melhoramento promovendo a resistência à seca, o objetivo deste trabalho foi avaliar as diferenças fisiológicas e de biomassa de cultivares de soja do tipo de crescim...

  12. Influencia del contacto precoz, nacionalidad, tipo de parto y prematuridad en la lactancia materna

    OpenAIRE

    Ana Belén Laviña Castan

    2015-01-01

    Conocer si en el HUMS existe asociación entre lactancia materna y nacionalidad, prematuridad, tipo de parto, contacto precoz piel con piel. Estudio de cohortes, en una muestra de 541 puérperas del HUMS en octubre-noviembre 2011. Las variables: nacionalidad, tipo de parto, contacto precoz, parto prematuro e inicio lactancia materna se recogieron antes del alta hospitalaria mediante cuestionario. A los dos meses postparto se contactó telefónicamente con las madres para conocer el tipo de lactan...

  13. Distintos tipos de células fotosensibles del sistema visual humano

    OpenAIRE

    Gómez García, Olga

    2016-01-01

    Existen en la retina dos tipos de células fotosensibles ampliamente conocidos, estos son los conos y los bastones. Hay tres tipos diferentes de conos, sensibles a distintas longitudes de onda, y un solo tipo de bastón, sensible a otra longitud de onda diferente. Los conos son los encargados de la visión en color y los bastones son altamente sensibles en luminancias bajas. Estos fotorreceptores, además de la generación y trasmisión de la información visual consciente, intervienen en la a...

  14. Annotations on Mexico's WISC-IV: a validity study.

    Science.gov (United States)

    Fina, Anthony D; Sánchez-Escobedo, Pedro; Hollingworth, Liz

    2012-01-01

    This project seeks to provide evidence on the internal structure of the Escala Wechsler de Inteligencia para Niños-IV (EWIN-IV; Wechsler, 2007a ) through a confirmatory factor analysis and intercorrelational study. Also provided is information on the adaptation process and other sources of validity evidence in support of the EWIN-IV norms. The standardization data for the EWIN-IV were used for all analyses. The factor loadings and correlational patterns found on the EWIN-IV are comparable to those seen in the American versions of the test. The proposed factor and scoring structure of the EWIN-IV was supported.

  15. Efecto de dos tipos de raciones y cuatro alojamientos sobre el comportamiento productivo de cerdas gestantes

    Directory of Open Access Journals (Sweden)

    H. Araque

    2012-01-01

    Full Text Available El experimento se realizó en la Facultad de Agronomía, Universidad Central de Venezuela, con el objeto de evaluar el comportamiento productivo de cerdas que recibieron dos tipos de dietas y se alojaron durante la fase de gestación en cuatro sistemas diferentes de alojamiento. Las dietas fueron: con base de recursos tradicionales (dt y formulada con recursos alternativos (ra: raíz de yuca, follaje de yuca y morera, y aceite de palma. Los sistemas de alojamiento fueron: cama profunda (cp, campo (cm corrales (co y jaulas (ja, bajo un diseño de experimento totalmente aleatorizado con arreglo de tratamiento factorial (2x4, con nueve repeticiones, utilizando la cerda como unidad experimental. Se usaron 72 cerdas de la línea genética Camborough 22 (18 por alojamiento y nueve por dieta. Los servicios de las cerdas se hicieron por inseminación artificial. Las variables medidas fueron: días de gestación, ganancia de espesor de grasa dorsal, ganancia total de peso, ganancia diaria de peso, consumo de alimento, conversión de alimento, lechones nacidos vivos y peso de la camada al nacer. No se encontraron diferencias (P>0,05 para la interacción de ambos factores, entre dietas y sistemas de alojamiento. Cerdas de alto potencial genético que realizaron el periodo de gestación en alojamientos alternativos (cm o cp, alimentadas con arreglos alimenticios elaborados con base de recursos autóctonos alternativos mostraron un comportamiento productivo satisfactorio, comparable con los sistemas convencionales de producción de cerdos, con la consecuente mejora del bienestar animal, siendo una alternativa factible para pequeños y medianos productores de cerdos.

  16. Endocardite bacteriana em paciente com diabetes mellitus tipo 2

    Directory of Open Access Journals (Sweden)

    Alcinda Aranha Nigri

    2016-10-01

    Full Text Available Introdução: A endocardite infecciosa é uma infecção microbiana da superfície do endocárdio. Acomete sobretudo valvas cardíacas, em geral, a mitral. Etiologias comuns são: uso de drogas injetáveis, infecção oral, hemodiálise a longo prazo e diabetes mellitus (DM. O diagnóstico é realizado por meio dos Critérios de Duke. Objetivos: Relatar caso de endocardite de paciente do Hospital Santa Lucinda (HSL. Metodologia: As informações foram obtidas pelo exame clínico, prontuário da paciente, relato da equipe médica e revisão de literatura. Relato de Caso: Paciente L.F.P.L., F., 54 anos, DM tipo 2, hipertensa, com insuficiência renal crônica não-dialítica, com úlceras de membros inferiores (MMII. Foi realizado debridamento e uso de antibiótico (ATB. Posteriormente, procurou hospital com queixa de dispneia. Diagnosticada com pneumonia (sic, usou ATB. A posteriori, apresentou anasarca e febre. Não houve leucocitose provavelmente devido ao uso de ATB. Constatou-se sopro mitral; no ecocardiograma: insuficiência mitral e tricúspide e vegetação em valva mitral, indicando endocardite infecciosa. Encaminhada ao HSL para cirurgia, apresentou na admissão: derrame pleural, hemo- e leucograma (LEU sem alterações, ureia 142, glicose 256 (mg/dL e albumina 2,6 (g/dL. Após 6 dias, foi inserida a prótese biomitral e cerclagem de valva tricúspide. Realizou-se transfusões sanguíneas pós-cirúrgicas. Manifestou parada cardiorrespiratória (PCR, realizada ressuscitação cardiopulmonar. Após 10 dias, apresentou arritmia, PCR, sepse e foi a óbito. Conclusões: O manejo adequado do DM pode evitar complicações, como úlceras de MMII, evitando, consequentemente, a disseminação via hematogênica e o quadro de endocardite. Deve-se considerar o uso prévio de ATB ao se analisar o LEU do paciente.

  17. CRESCIMENTO INICIAL DE KIWANO EM DIFERENTES TIPOS DE SUBSTRATOS

    Directory of Open Access Journals (Sweden)

    Omar Schmildt

    2012-12-01

    Full Text Available The kiwano (Cucumis metuliferus is an exotic species, belonging to the Cucurbitaceae family, possessing a great potential for commercialization. This study aimed to learn more about the culture of kiwanothrough its initial growth on different substrates, since there are few works related to this culture. The study was carried out in a greenhouse in Alegre-ES, a completely randomized design with four replications. The treatmentsconsisted of the following substrates: Plantmax®, composed of legume Acacia sp; composed of rice husk carbornized + humus, composed of corn stover + manure and compost humus + vermiculite. At 28 days after sowing wereevaluated height, fresh weight and dry weight of seedlings. The substrate Plantmax® was more effective in the initial spread of the kiwano, with statistically higher in those variables and is therefore suitable for the production ofseedlings of this crop.O kiwano (Cucumis metuliferus é uma espécie exótica, pertencente à família das Cucurbitáceas, possuindo um grande potencial para comercialização. Este trabalho teve como objetivo conhecer mais sobre a cultura do kiwano, através do seu crescimento inicial em diferentes tipos de substratos, visto que são poucos os trabalhos relacionados com esta cultura. O trabalho foi realizado em casa de vegetação, em Alegre-ES, num delineamento inteiramente casualizado com quatro repetições. Os tratamentos utilizados foram constituídos dos seguintes substratos: Plantmax®; composto de leguminosa Acacia sp; composto de casca de arroz carbonizada + húmus; composto de palha de milho + esterco; e composto de vermiculita + húmus. Aos 28 dias após a semeadura foram avaliadas a altura, a massa de matéria fresca e a massa de matéria seca das plântulas. O substrato Plantmax®se mostrou mais eficiente na propagação inicial do kiwano, apresentando médias estatisticamente superiores para asvariáveis analisadas, sendo, portanto indicado para a produção de

  18. Interação genótipo x ambiente em genótipos de feijão-caupi semiprostrado via modelos mistos

    Directory of Open Access Journals (Sweden)

    Francisco Eduardo Torres

    2015-01-01

    Full Text Available A metodologia de modelos mistos (REML/BLUP tem sido empregada para estudar os efeitos da interação genótipo x ambiente (G x E em várias culturas, como: arroz, feijão, cana-de-açúcar, cajueiro e eucalipto, porém ainda não foi aplicada em feijão-caupi. Assim, o objetivo deste trabalho foi selecionar simultaneamente genótipos de feijão-caupi semiprostrado cultivados no Estado do Mato Grosso do Sul, via modelos mistos, que reúnam alta adaptabilidade, estabilidade e produtividade de grãos. Foram conduzidos quatro ensaios de valor de cultivo e uso com genótipos de genótipos de feijão-caupi nos anos de 2005 e 2006 em Aquidauana, Chapadão do Sul e Dourados. O delineamento experimental utilizado foi o de blocos completos casualizados, com 20 genótipos e 4 repetições. Os parâmetros genéticos foram estimados pela metodologia REML/BLUP, e a seleção baseou-se no método da média harmônica do desempenho relativo dos valores genéticos (MHPRVG, em três estratégias: seleção com base no valor genético predito, tendo-se considerado o desempenho médio dos genótipos em todos os ambientes (sem efeito de interação ou o desempenho em cada ambiente (com efeito da interação; e seleção simultânea quanto à produtividade de grãos, estabilidade e adaptabilidade. Os genótipos BRS Paraguaçu, MNC99-542F-5 e MNC99-508G-1 podem ser cultivados em vários ambientes, pois reúnem alta produtividade de grãos, adaptabilidade e estabilidade. A herdabilidade da média dos genótipos apresentou magnitude variando de moderada a alta, fato que indica excelentes possibilidades para a seleção, permitindo acurácia seletiva de 82%.

  19. [Fe IV] Emission in Ionized Nebulae

    Directory of Open Access Journals (Sweden)

    M. Rodríguez

    2003-01-01

    Full Text Available Se presentan los resultados de un análisis de la emisión en [Fe IV] en varias nebulosas ionizadas, basado en nuevas identificaciones y medidas anteriores de líneas de [Fe IV]. Las abundancias de Fe obtenidas al sumar las abundancias de los iones relevantes (principalmente Fe++ y Fe3+ resultan ser menores, por factores en el rango 2.6-5.9, que las abundancias implicadas por las líneas de [Fe III] y un factor de corrección por la ionizacion obtenido con modelos de ionizacion. Se discuten las posibles razones de esta discrepancia así como las implicaciones que tiene para nuestro entendimiento tanto de la evolución del polvo en nebulosas ionizadas como de la historia química de galaxias de baja metalicidad.

  20. Fluctuations in type IV pilus retraction

    CERN Document Server

    Linden, M; Jonsson, A B; Wallin, M; Linden, Martin; Johansson, Emil; Jonsson, Ann-Beth; Wallin, Mats

    2005-01-01

    The type IV pilus retraction motor is found in many important bacterial pathogens. It is the strongest known linear motor protein and is required for bacterial infectivity. We characterize the dynamics of type IV pilus retraction in terms of a stochastic chemical reaction model. We find that a two state model can describe the experimental force velocity relation and qualitative dependence of ATP concentration. The results indicate that the dynamics is limited by an ATP-dependent step at low load and a force-dependent step at high load, and that at least one step is effectively irreversible in the measured range of forces. The irreversible nature of the sub-step(s) lead to interesting predictions for future experiments: We find different parameterizations with mathematically identical force velocity relations but different fluctuations (diffusion constant). We also find a longer elementary step compared to an earlier analysis, which agrees better with known facts about the structure of the pilus filament and e...

  1. Soome-ugri IV maailmakongressi kunstiprogramm

    Index Scriptorium Estoniae

    2004-01-01

    Soome-ugri IV maailmakongressi kultuuriprogrammi raames toimub Sagadis Tiiu Kirsipuu kureeritud puuskulptuuri sümpoosion "Ilmapuu". 8. augustist on soome-ugri kunstnikud Anatoli Stepanov, Nikolai Bõkov, Marja-Liisa Mäki-Penttilä, Jakov Jakovlev, Reino Saijets, Jozsef Lukacs, Anatoli Punegov, Pjotr Rjabov, Elo Liiv ja Urmas Rauba teinud puuskulptuure, mida eksponeeritakse kongressi toimumise ajal Tallinnas. Urmas Sisaski kontsert mõisapargis

  2. Dipyridinium tribromidochloridobis(4-chlorophenylstannate(IV

    Directory of Open Access Journals (Sweden)

    Kong Mun Lo

    2009-06-01

    Full Text Available The tin atom in the substituted ammonium stannate(IV, (C5H6N2[SnBr3(C6H4Cl2Cl], lies on a center of symmetry in a distorted octahedral coordination geometry. Each independent halogen site is occupied by bromine and chlorine anions in an approximate 3:1 ratio. The pyridinium cation forms a hydrogen bond to only one of the halogen atoms.

  3. Examining Computational Assumptions For Godiva IV

    Energy Technology Data Exchange (ETDEWEB)

    Kirkland, Alexander Matthew [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Jaegers, Peter James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-08-11

    Over the course of summer 2016, the effects of several computational modeling assumptions with respect to the Godiva IV reactor were examined. The majority of these assumptions pertained to modeling errors existing in the control rods and burst rod. The Monte Carlo neutron transport code, MCNP, was used to investigate these modeling changes, primarily by comparing them to that of the original input deck specifications.

  4. Generation-IV Nuclear Energy Systems

    Science.gov (United States)

    McFarlane, Harold

    2008-05-01

    Nuclear power technology has evolved through roughly three generations of system designs: a first generation of prototypes and first-of-a-kind units implemented during the period 1950 to 1970; a second generation of industrial power plants built from 1970 to the turn of the century, most of which are still in operation today; and a third generation of evolutionary advanced reactors which began being built by the turn of the 20^th century, usually called Generation III or III+, which incorporate technical lessons learned through more than 12,000 reactor-years of operation. The Generation IV International Forum (GIF) is a cooperative international endeavor to develop advanced nuclear energy systems in response to the social, environmental and economic requirements of the 21^st century. Six Generation IV systems under development by GIF promise to enhance the future contribution and benefits of nuclear energy. All Generation IV systems aim at performance improvement, new applications of nuclear energy, and/or more sustainable approaches to the management of nuclear materials. High-temperature systems offer the possibility of efficient process heat applications and eventually hydrogen production. Enhanced sustainability is achieved primarily through adoption of a closed fuel cycle with reprocessing and recycling of plutonium, uranium and minor actinides using fast reactors. This approach provides significant reduction in waste generation and uranium resource requirements.

  5. DNA ligase IV syndrome; a review.

    Science.gov (United States)

    Altmann, Thomas; Gennery, Andrew R

    2016-10-07

    DNA ligase IV deficiency is a rare primary immunodeficiency, LIG4 syndrome, often associated with other systemic features. DNA ligase IV is part of the non-homologous end joining mechanism, required to repair DNA double stranded breaks. Ubiquitously expressed, it is required to prevent mutagenesis and apoptosis, which can result from DNA double strand breakage caused by intracellular events such as DNA replication and meiosis or extracellular events including damage by reactive oxygen species and ionising radiation.Within developing lymphocytes, DNA ligase IV is required to repair programmed DNA double stranded breaks induced during lymphocyte receptor development.Patients with hypomorphic mutations in LIG4 present with a range of phenotypes, from normal to severe combined immunodeficiency. All, however, manifest sensitivity to ionising radiation. Commonly associated features include primordial growth failure with severe microcephaly and a spectrum of learning difficulties, marrow hypoplasia and a predisposition to lymphoid malignancy. Diagnostic investigations include immunophenotyping, and testing for radiosensitivity. Some patients present with microcephaly as a predominant feature, but seemingly normal immunity. Treatment is mainly supportive, although haematopoietic stem cell transplantation has been used in a few cases.

  6. Tratamiento de una maloclusión clase II división 1 utilizando un aparato expansor y exodoncias de 4 primeras premolares / Tratamiento de una maloclusión clase II división 2 tipo B utilizando un aparato distalizador / Tratamiento de camuflaje de una maloclusión clase III con exodoncia de un incisivo central inferior / Tratamiento de una maloclusión clase I por biprotrusión y DAD con exodoncias de 4 primeras premolares / Tratamiento de una maloclusión clase I por DAD con extracciones asimétricas

    OpenAIRE

    González Torres, Carlos Rodrigo

    2015-01-01

    Describe el tratamiento de cinco casos clínicos de ortodoncia, atendidos en la Clínica Especializada de la Facultad de Odontología de la Universidad de San Martín de Porres durante el periodo Agosto 2009 - Marzo 2012, tratándose de: 1. Tratamiento de una maloclusión clase II división 1 utilizando un aparato expansor y exodoncias de 4 primeras premolares. 2. Tratamiento de una maloclusión clase II división 2 tipo B utilizando un aparato distalizador. 3. Tratamiento de camuflaje de una...

  7. Diabetes tipo 2 en niños. Serie de casos

    OpenAIRE

    Manrique-Hurtado, Helard; Aro-Guardia, Pedro; Pinto-Valdivia, Miguel

    2015-01-01

    Objetivos: Describir las características clínicas y bioquímicas de un grupo de niños y adolescentes con diagnóstico reciente de diabetes tipo 2. Material y métodos: Estudio descriptivo, retrospectivo, tipo de serie de casos. Se definió caso al niño o adolescente con glucosa plasmática en ayunas mayor a 126 mg/dl, ausencia de antiGAD y péptido C mayor a 1,5 ng/dl. Se excluyeron a los pacientes con diagnóstico previo de diabetes mellitus tipo 1, diabetes tipo MODY o diabetes secundaria a uso de...

  8. Wolf-Rayet Central Stars and the Binary Evolution Channel

    Directory of Open Access Journals (Sweden)

    Orsola De Marco

    2003-01-01

    Full Text Available Cálculos recientes de la evolución de estrellas sencillas han tenido éxito en reproducir la composicion de estrellas Wolf-Rayet (WR deficientes en hidrogeno que son además estrellas centrales de nebulosas planetarias. Sin embargo, las observaciones infrarrojas mas recientes dejan claro que el esquema de estrellas sencillas no concuerda con las propiedades del polvo que rodea a muchas estrellas centrales tipo WR. Por otro lado, la binariedad podría explicar las observaciones en el infrarrojo asi como ofrecer una posibilidad de remover la envoltura rica en H de la estrella. En este trabajo proponemos dos esquemas con estrellas binarias originalmente propuestos por De Marco & Soker en relación a las estrellas centrales tipo WR. En el primero, un sistema binario cercano da como resultado el regreso de material eyectado a la estrella y eventualmente una estrella central deficiente en H. Este esquema se invoca para explicar la estrella central CPD-56º8032 en [WC10] y su disco de polvo. El segundo esquema propone que la mayoría de las estrellas centrales tipo WR son resultado de una fusión con una compañera de baja masa durante la fase AGB. Modelamos este esquema por medio de simulaciones hidrodinámicas en 3D, que simulan la fase de envolvente común entre una estrella AGB y una compañera de entre 0.1 and 0.2-M๏ durante el primer y décimo pulso térmico.

  9. E1B 55k-independent dissociation of the DNA ligase IV/XRCC4 complex by E4 34k during adenovirus infection.

    Science.gov (United States)

    Jayaram, Sumithra; Gilson, Timra; Ehrlich, Elana S; Yu, Xiao-Fang; Ketner, Gary; Hanakahi, Les

    2008-12-20

    The ligase IV/XRCC4 complex plays a central role in DNA double-strand break repair by non-homologous end joining (NHEJ). During adenovirus infection, NHEJ is inhibited by viral proteins E4 34k and E1B 55k, which redirect the Cul5/Rbx1/Elongin BC ubiquitin E3 ligase to polyubiquitinate and promote degradation of ligase IV. In cells infected with E1B 55k-deficient adenovirus, ligase IV could not be found in XRCC4-containing complexes and was observed in a novel ligase IV/E4 34k/Cul5/Elongin BC complex. These observations suggest that dissociation of the ligase IV/XRCC4 complex occurs at an early stage in E4 34k-mediated degradation of ligase IV and indicate a role for E4 34k in dissociation of the ligase IV/XRCCC4 complex. Expression of E4 34k alone was not sufficient to dissociate the ligase IV/XRCC4 complex, which indicates a requirement for an additional, as yet unidentified, factor in E1B 55k-independent dissociation of the ligase IV/XRCC4 complex.

  10. Planning a Kinetic and Mechanistic Study with Cerium (IV)

    Science.gov (United States)

    Hanna, Samir B.; And Others

    1976-01-01

    Presents a kinetic study that utilizes a method for varying the concentrations of the possible Ce(IV) species and computing the concentration distribution of the sulfato and hydroxo species of Ce(IV). (MLH)

  11. Synthesis and evaluation of artificial antigens for astragaloside IV

    Directory of Open Access Journals (Sweden)

    Sheng-lan Yu

    2014-06-01

    Full Text Available The objective of this study was to produce artificial antigens for astragaloside IV that could be used to prepare antibodies against astragaloside IV screened in Radix astragali (Astragalus membranaceus (Fisch Bunge, Fabaceae and its preparations, using an indirect ELISA. Astragaloside IV was coupled to carrier proteins, bovine serum albumin and ovalbumin using the sodium periodate method and was then evaluated using SDS-PAGE, MALDI-TOF MS and animal immunizations. The coupling ratio of astragaloside IV to bovine serum albumin ratio was determined to be thirteen, and the indirect ELISA demonstrated that three groups of mice immunized with astragaloside IV-bovine serum albumin produced anti-astragaloside IV- bovine serum albumin-specific antibody, with a minimum serum titer of 1:9600. A method for synthesizing highly immunogenic astragaloside IV artificial antigens was successfully developed thus indicating its feasibility in the establishment of a fast immunoassay for astragaloside IV content determination in Radix astragali and its products.

  12. Estudo do cronótipo de um grupo de trabalhadores em turnos

    Directory of Open Access Journals (Sweden)

    Milva Maria Figueiredo de Martino

    Full Text Available Neste estudo, os objetivos foram descrever as características de matutinidade/vespertinidade de um grupo de trabalhadores em turnos de uma indústria química e identificar possíveis associações entre cronótipo e turno de trabalho. A pesquisa foi realizada em uma indústria química do interior do estado de São Paulo. Os trabalhadores lotados nesta seção eram distribuídos em dois turnos: matutino e vespertino. A amostra constituiu-se de 44 trabalhadores, dos sexos feminino e masculino, que trabalhavam em ambos os turnos. Os dados foram coletados com a versão brasileira do questionário de identificação de indivíduos matutinos e vespertinos que foi elaborado por Horne & Östberg (1976. Foi verificado o predomínio do cronótipo "moderadamente matutino" - MM (n = 21 ou 47,73% -, seguido pelo tipo "Indiferente" - IN (n = 12 ou 27,27% - e pelo tipo "definitivamente matutino" - DM (n = 10 ou 22,73%. Somente um indivíduo foi classificado como "definitivamente vespertino" - DV (2,27%. Entre os trabalhadores estudados houve predomínio do cronótipo "moderadamente matutino" seguido do tipo "indiferente" e do tipo "definitivamente matutino". Não foram verificadas associações estatisticamente significativas entre o cronótipo e as características individuais neste estudo.

  13. La victimología como ciencia : tipos de víctimas

    OpenAIRE

    Liñares Lobón, Pablo

    2013-01-01

    El tratamiento de los diversos tipos de víctimas ha sido objeto de estudio de la perspectiva psicológica desde los últimos años. En este sentido, es tan vital conocer bien los tipos de víctimas como las herramientas metodológicas que son utilizadas en los programas de intervención que aporten soluciones reales al problema

  14. Tipos de propiedad y comportamiento estratégico de la empresa

    OpenAIRE

    2001-01-01

    Esta tesis tiene como principal objetivo profundizar en el entendimiento de los efectos de diferentes tipos de propietarios como factor determinante de los objetivos y de las decisiones empresariales en presencia de problemas informativos. La investigacion trata de explicar algunas de las consecuencias que tiene en el comportamiento estrategico de las empresas participadas, la existencia de distintos tipos de inversores estables, bien informados y con capacidad de control, como son los grupos...

  15. Material tipo de insectos en el Laboratorio de Sanidad Vegetal, SENASA, Lima, Perú

    Directory of Open Access Journals (Sweden)

    Pedro W. Lozada

    2013-05-01

    Full Text Available Se presenta la lista de material tipo de Insecta depositado en la colección del Laboratorio de Sanidad Vegetal, Servicio Nacional de Sanidad Agraria (SENASA, Lima, Perú, comprendiendo 21 especies de Psylloidea (Hemiptera, 4 de Cicadellidae (Hemiptera, 4 de Curculionidae (Coleoptera y 2 de Tachinidae (Diptera, todas provenientes de localidades peruanas. Los tipos de Tachinidae descritos por Charles Townsend no han sido incluidos en esta relación.

  16. Nuevas estrategias terapéuticas en diabetes mellitus tipo 1

    OpenAIRE

    Barajas, M. (Miguel); Príncipe, R.M. (R.M.); Escalada, J.; Prosper, F. (Felipe); J. Salvador

    2008-01-01

    El principal determinante del riesgo de complicaciones derivadas de la diabetes mellitus tipo 1 se debe a los altos niveles de glucosa en sangre mantenidos durante largo tiempo. Para conseguir un beneficio terapéutico en pacientes con diabetes mellitus es necesario desarrollar tratamientos que permitan de manera segura, efectiva y estable mantener la normoglucemia. Lamentablemente, el tratamiento de la diabetes mellitus tipo 1 mediante el aporte exógeno de insulina no ...

  17. Density diagnostics derived from the O iv and S iv intercombination lines observed by IRIS

    Science.gov (United States)

    Polito, V.; Del Zanna, G.; Dudík, J.; Mason, H. E.; Giunta, A.; Reeves, K. K.

    2016-10-01

    The intensity of the O iv 2s2 2p 2P-2s2p24P and S iv 3 s2 3p 2P-3s 3p24 P intercombination lines around 1400 Å observed with the Interface Region Imaging Spectrograph (IRIS) provide a useful tool to diagnose the electron number density (Ne) in the solar transition region plasma. We measure the electron number density in a variety of solar features observed by IRIS, including an active region (AR) loop, plage and brightening, and the ribbon of the 22-June-2015 M 6.5 class flare. By using the emissivity ratios of O iv and S iv lines, we find that our observations are consistent with the emitting plasma being near isothermal (logT[K] ≈ 5) and iso-density (Ne ≈ 1010.6 cm-3) in the AR loop. Moreover, high electron number densities (Ne ≈ 1013 cm-3) are obtained during the impulsive phase of the flare by using the S iv line ratio. We note that the S iv lines provide a higher range of density sensitivity than the O iv lines. Finally, we investigate the effects of high densities (Ne ≳ 1011 cm-3) on the ionization balance. In particular, the fractional ion abundances are found to be shifted towards lower temperatures for high densities compared to the low density case. We also explored the effects of a non-Maxwellian electron distribution on our diagnostic method. The movie associated to Fig. 3 is available at http://www.aanda.org

  18. Linfoma do sistema nervoso central: ensaio iconográfico

    Directory of Open Access Journals (Sweden)

    Fabiano Reis

    2013-04-01

    Full Text Available Ilustramos este ensaio iconográfico de linfoma do sistema nervoso central com imagens de ressonância magnética obtidas em nosso serviço nos últimos 13 anos e discutimos algumas das principais características radiológicas deste tipo de linfoma, primário e secundário. O linfoma sistema nervoso central é um tumor relativamente infrequente, mas alguns achados na ressonância magnética podem sugerir este diagnóstico.

  19. Genótipos de haptoglobina e hipertensão refratária em pacientes com diabete melito tipo 2

    Directory of Open Access Journals (Sweden)

    Vânia Pereira Albuquerque Wobeto

    2011-10-01

    Full Text Available FUNDAMENTO: Tem sido sugerido que o polimorfismo da haptoglobina pode influenciar na patogênese das complicações microvasculares e macrovasculares em pacientes diabéticos. OBJETIVO: O objetivo principal deste estudo transversal foi de realizar uma investigação da existência ou não de uma associação entre os genótipos de haptoglobina e a prevalência de eventos isquêmicos cardiovasculares (angina estável, angina instável e infarto agudo do miocárdio, hipertensão arterial sistêmica, hipertensão refratária, obesidade e dislipidemia em 120 pacientes com diabete melito tipo 2, seguidos no Hospital Universitário da Unicamp, em Campinas, Estado de São Paulo. MÉTODOS: A genotipagem da haptoglobina foi realizada por reações em cadeia da polimerase alelo-específicas. As frequências dos genótipos de haptoglobina foram comparadas com a presença/ausência de doença cardiovascular, hipertensão arterial sistêmica, hipertensão refratária, obesidade e dislipidemia; medições de pressão arterial sistólica e diastólica; glicemia, colesterol (total, lipoproteínas de alta densidade - HDL e lipoproteínas de baixa densidade - LDL e triglicerídeos; assim como níveis de creatinina sérica. RESULTADOS: Embora nenhuma associação entre o genótipo de haptoglobina e a presença de doença cardiovascular tenha sido identificada, encontramos um excesso significativo de pacientes com o genótipo Hp2-1 entre as pessoas com hipertensão refratária, que também apresentavam uma maior pressão arterial sistólica e diastólica e níveis de colesterol total e LDL. CONCLUSÃO: Nossos resultados sugerem que os pacientes com diabete melito tipo 2 com o genótipo Hp2-1 podem apresentar uma maior chance de desenvolver hipertensão refratária. Estudos adicionais em populações diabéticas são necessários para confirmar esses achados.

  20. Resistência de genótipos de feijoeiro a Bemisia tabaci biótipo B Resistance of bean genotypes to Bemisia tabaci biotype B

    Directory of Open Access Journals (Sweden)

    Lucas Castro Torres

    2012-01-01

    Full Text Available O estudo de genótipos de feijoeiro resistentes à mosca-branca Bemisia tabaci (Genn. biótipo B (Hemiptera: Aleyrodidae é de grande importância devido aos danos ocasionados por essa praga à cultura. Neste trabalho, foram estudados a atratividade para adultos, a preferência para oviposição em testes com e sem chance de escolha, o ciclo ovo-adulto e o tipo e número de tricomas presentes nos folíolos. Os experimentos foram realizados em casa de vegetação avaliando-se, inicialmente, cem genótipos de feijoeiro. A resistência do tipo não-preferência para alimentação e/ou antibiose foi observada nos genótipos ARC-3, IAC-Alvorada e Canário 101, sendo a emergência de adultos fortemente influenciada pelos genótipos. Também se observou correlação negativa moderada entre o número de ovos e o número de tricomas glandulares, e correlação positiva muito forte entre o número de ovos e o número de tricomas tectores unciformes.The study of bean genotypes resistant to the whitefly Bemisia tabaci (Genn. B biotype (Hemiptera: Aleyrodidae has been of great importance due to the damage caused by this pest. In this research, bean genotypes were evaluated regarding attractiveness to whitefly adults, the preference for oviposition in free-choice and non choice tests, egg-to-adult development time and characterized for the presence, type and number of trichomes. The experiments were carried out under greenhouse conditions initially evaluating 100 bean genotypes. The non-preference type of resistance for feeding and/or antibiosis was observed in the genotypes ARC-3, IAC-Alvorada and Canário 101, and the emergence of adults was strongly influenced by the genotypes. It was also observed a moderate negative correlation between the number of eggs and the number of glandular trichomes, as well as a very strong positive correlation between the number of eggs and the number of unciform non-glandular trichomes.

  1. 40 CFR 144.23 - Class IV wells.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Class IV wells. 144.23 Section 144.23... INJECTION CONTROL PROGRAM Authorization of Underground Injection by Rule § 144.23 Class IV wells. (a) Injection into existing Class IV wells is authorized for up to six months after approval or promulgation...

  2. 78 FR 45592 - DeltaPoint Capital IV, LP;

    Science.gov (United States)

    2013-07-29

    ... ADMINISTRATION DeltaPoint Capital IV, LP; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that DeltaPoint Capital IV, L.P., 45 East Avenue... Business Administration (``SBA'') Rules and Regulations (13 CFR 107.730). DeltaPoint Capital IV,...

  3. 29 CFR 4022.63 - Estimated title IV benefit.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Estimated title IV benefit. 4022.63 Section 4022.63 Labor... PAYABLE IN TERMINATED SINGLE-EMPLOYER PLANS Benefit Reductions in Terminating Plans § 4022.63 Estimated... administrator shall determine each participant's estimated title IV benefit. The estimated title IV...

  4. Surgical decision making for stage IV adult acquired flatfoot disorder.

    Science.gov (United States)

    Peterson, Kyle S; Hyer, Christopher F

    2014-07-01

    Adult acquired flatfoot deformity is a debilitating musculoskeletal condition affecting the lower extremity. Posterior tibial tendon dysfunction (PTTD) is the primary etiology for the development of a flatfoot deformity in an adult. PTTD is classified into 4 stages (with stage IV subdivided into stage IV-A and IV-B). This classification is described in detail in this article.

  5. Meningoencephalitis by Herpesvirus Type 5/ Herpesvírus Bovino Tipo 5 e Meningoencefalite Herpética Bovina

    Directory of Open Access Journals (Sweden)

    Amauri Alcindo Alfieri

    2002-05-01

    Full Text Available Bovine herpesvirus type 5 is an important pathogen in young and adult cattle and causes meningoencephalitis. The infection, although it causes low morbidity, can cause a lethality rate close to 100%. Diagnosis of the clinical disease is very important due to the similarities with other diseases that affect the cattle central nervous system, especially rabies. This revision aims to present topics related to the etiological agent, the disease, diagnosis and prophylaxis methods of bovine herpetic meningoencephalitis.O herpesvírus bovino tipo 5 é um importante patógeno de bovinos jovens e adultos, e o agente etiológico da meningoencefalite herpética. A infecção, apesar da baixa morbidade, pode ocasionar taxa de letalidade próxima a 100%. Devido às semelhanças com outras enfermidades que comprometem o sistema nervoso central de bovinos, em particular a raiva, o diagnóstico da doença clínica assume especial importância. Esta revisão tem por objetivo apresentar tópicos relacionados ao agente etiológico, à doença e aos métodos de diagnóstico e de profilaxia da meningoencefalite herpética bovina.

  6. Expanding the Ecological Validity of WAIS-IV and WMS-IV With the Texas Functional Living Scale

    OpenAIRE

    Drozdick, Lisa Whipple; Cullum, C. Munro

    2010-01-01

    Assessment of functional status is an important aspect of clinical evaluation. As part of the standardization of the Wechsler Adult Intelligence Scale–Fourth Edition (WAIS-IV) and Wechsler Memory Scale–Fourth Edition (WMS-IV), participants completed the Texas Functional Living Scale (TFLS), a measure of Instrumental Activities of Daily Living. The relationships between TFLS and WAIS-IV and WMS-IV were examined in both normally developing and clinical samples. In general, the highest correlati...

  7. Somatoform disorders and rheumatic diseases: from DSM-IV to DSM-V

    Directory of Open Access Journals (Sweden)

    A. Alciati

    2014-06-01

    Full Text Available Medically unexplained symptoms are considered ‘somatoform disorders’ in the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV. The introduction of this nosographic category has been helpful in drawing attention to a previously neglected area, but has not been successful in promoting an understanding of the disorders’ biological basis and treatment implications, probably because of a series of diagnostic shortcomings. The newly proposed DSM-V diagnostic criteria try to overcome the limitations of the DSM-IV definition, which was organised centrally around the concept of medically unexplained symptoms, by emphasising the extent to which a patient’s thoughts, feelings and behaviours concerning their somatic symptoms are disproportionate or excessive. This change is supported by a growing body of evidence showing that psychological and behavioural features play a major role in causing patient disability and maintaining high level of health care use. Pain disorders is the sub-category of DSM-IV somatoform disorders that most closely resembles fibromyalgia. Regardless of the diagnostic changes recently brought about by DSM-V, neuroimaging studies have identified important components of the mental processes associated with a DSM- IV diagnosis of pain disorder.

  8. Somatoform disorders and rheumatic diseases: from DSM-IV to DSM-V.

    Science.gov (United States)

    Alciati, A; Atzeni, F; Sgiarovello, P; Sarzi-Puttini, P

    2014-06-06

    Medically unexplained symptoms are considered 'somatoform disorders' in the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). The introduction of this nosographic category has been helpful in drawing attention to a previously neglected area, but has not been successful in promoting an understanding of the disorders' biological basis and treatment implications, probably because of a series of diagnostic shortcomings. The newly proposed DSM-V diagnostic criteria try to overcome the limitations of the DSM-IV definition, which was organised centrally around the concept of medically unexplained symptoms, by emphasising the extent to which a patient's thoughts, feelings and behaviours concerning their somatic symptoms are disproportionate or excessive. This change is supported by a growing body of evidence showing that psychological and behavioural features play a major role in causing patient disability and maintaining high level of health care use. Pain disorders is the sub-category of DSM-IV somatoform disorders that most closely resembles fibromyalgia. Regardless of the diagnostic changes recently brought about by DSM-V, neuroimaging studies have identified important components of the mental processes associated with a DSM- IV diagnosis of pain disorder.

  9. Revisiting Case IV: a reassessment of bias and standard errors of Case IV under range restriction.

    Science.gov (United States)

    Fife, Dustin A; Mendoza, Jorge L; Terry, Robert

    2013-11-01

    In 2004, Hunter and Schmidt proposed a correction (called Case IV) that seeks to estimate disattenuated correlations when selection is made on an unmeasured variable. Although Case IV is an important theoretical development in the range restriction literature, it makes an untestable assumption, namely that the partial correlation between the unobserved selection variable and the performance measure is zero. We show in this paper why this assumption may be difficult to meet and why previous simulations have failed to detect the full extent of bias. We use meta-analytic literature to investigate the plausible range of bias. We also show how Case IV performs in terms of standard errors. Finally, we give practical recommendations about how the contributions of Hunter and Schmidt (2004) can be extended without making such stringent assumptions.

  10. Topological characterisation and identification of critical domains within glucosyltransferase IV (GtrIV of Shigella flexneri

    Directory of Open Access Journals (Sweden)

    Nair Anesh

    2011-12-01

    Full Text Available Abstract Background The three bacteriophage genes gtrA, gtrB and gtr(type are responsible for O-antigen glucosylation in Shigella flexneri. Both gtrA and gtrB have been demonstrated to be highly conserved and interchangeable among serotypes while gtr(type was found to be specific to each serotype, leading to the hypothesis that the Gtr(type proteins are responsible for attaching glucosyl groups to the O-antigen in a site- and serotype- specific manner. Based on the confirmed topologies of GtrI, GtrII and GtrV, such interaction and attachment of the glucosyl groups to the O-antigen has been postulated to occur in the periplasm. Results In this study, the topology of GtrIV was experimentally determined by creating different fusions between GtrIV and a dual-reporter protein, PhoA/LacZ. This study shows that GtrIV consists of 8 transmembrane helices, 2 large periplasmic loops, 2 small cytoplasmic N- and C- terminal ends and a re-entrant loop that occurs between transmembrane helices III and IV. Though this topology differs from that of GtrI, GtrII, GtrV and GtrX, it is very similar to that of GtrIc. Furthermore, both the N-terminal periplasmic and the C-terminal periplasmic loops are important for GtrIV function as shown via a series of loop deletion experiments and the creation of chimeric proteins between GtrIV and its closest structural homologue, GtrIc. Conclusion The current study provides the basis for elucidating the structure and mechanism of action of this important O-antigen modifying glucosyltransferase.

  11. MAJOR CONTRIBUTOR TO AGN FEEDBACK: VLT X-SHOOTER OBSERVATIONS OF S IV BALQSO OUTFLOWS

    Energy Technology Data Exchange (ETDEWEB)

    Borguet, Benoit C. J.; Arav, Nahum; Edmonds, Doug; Chamberlain, Carter [Department of Physics, Virginia Tech, Blacksburg, VA 24061 (United States); Benn, Chris, E-mail: b.borguet@alumni.ulg.ac.be [Isaac Newton Group, Apartado 321, E-38700 Santa Cruz de La Palma (Spain)

    2013-01-01

    We present the most energetic BALQSO outflow measured to date, with a kinetic luminosity of at least 10{sup 46} erg s{sup -1}, which is 5% of the bolometric luminosity of this high Eddington ratio quasar. The associated mass-flow rate is 400 solar masses per year. Such kinetic luminosity and mass-flow rate should provide strong active galactic nucleus feedback effects. The outflow is located at about 300 pc from the quasar and has a velocity of roughly 8000 km s{sup -1}. Our distance and energetic measurements are based in large part on the identification and measurement of S IV and S IV* broad absorption lines (BALs). The use of this high-ionization species allows us to generalize the result to the majority of high-ionization BALQSOs that are identified by their C IV absorption. We also report the energetics of two other outflows seen in another object using the same technique. The distances of all three outflows from the central source (100-2000 pc) suggest that we observe BAL troughs much farther away from the central source than the assumed acceleration region of these outflows (0.01-0.1 pc).

  12. El cambio en la designación general de material (DGM de las AACR a las RDA: Definición de los atributos tipo de contenido, tipo de medio y tipo de soporte

    Directory of Open Access Journals (Sweden)

    Paola Andrea Picco Gómez

    2012-04-01

    Full Text Available Se aborda el estudio de los atributos tipo de contenido, tipo de medio y tipo de soporte definidos por el código de catalogación Resource Description and Access (RDA para solucionar los problemas que presentaba la lista de términos utilizadas para registrar la designación general de material (DGM en las Anglo American Cataloging Rules (AACR. Los términos eran ambiguos combinando aspectos referidos al contenido y clase de material del recurso. Se parte de una exhaustiva revisión bibliográfica y del estudio de los documentos que se generaron en el proceso de elaboración del nuevo código. Se menciona el trabajo conjunto entre el Joint Steering Committee (JSC y el estándar ONIX para el establecimiento de criterios que permitieron definir estos tres atributos, así como el aporte del modelo FRBR en la definición de los mismos. Se presentan ejemplos de registros bibliográficos donde se utilizan estos tres atributos en formato MARC21, ISBD consolidada a partir de la definición del área 0 y en el esquema de metadatos Dublin Core. Se finaliza destacando la necesidad de continuar con investigaciones que permitan concluir sobre la adecuación de estos tres atributos a las necesidades de los catalogadores, usuarios y a la realidad tecnológica

  13. New Materials for NGNP/Gen IV

    Energy Technology Data Exchange (ETDEWEB)

    Robert W. Swindeman; Douglas L. Marriott

    2009-12-18

    The bounding conditions were briefly summarized for the Next Generation Nuclear Plant (NGNP) that is the leading candidate in the Department of Energy Generation IV reactor program. Metallic materials essential to the successful development and proof of concept for the NGNP were identified. The literature bearing on the materials technology for high-temperature gas-cooled reactors was reviewed with emphasis on the needs identified for the NGNP. Several materials were identified for a more thorough study of their databases and behavioral features relative to the requirements ASME Boiler and Pressure Vessel Code, Section III, Division 1, Subsection NH.

  14. Research in collegiate mathematics education IV

    CERN Document Server

    Dubinsky, Ed; Kaput, Jim

    2001-01-01

    This fourth volume of Research in Collegiate Mathematics Education (RCME IV) reflects the themes of student learning and calculus. Included are overviews of calculus reform in France and in the U.S. and large-scale and small-scale longitudinal comparisons of students enrolled in first-year reform courses and in traditional courses. The work continues with detailed studies relating students' understanding of calculus and associated topics. Direct focus is then placed on instruction and student comprehension of courses other than calculus, namely abstract algebra and number theory. The volume co

  15. Gen IV Materials Handbook Functionalities and Operation

    Energy Technology Data Exchange (ETDEWEB)

    Ren, Weiju [ORNL

    2009-12-01

    This document is prepared for navigation and operation of the Gen IV Materials Handbook, with architecture description and new user access initiation instructions. Development rationale and history of the Handbook is summarized. The major development aspects, architecture, and design principles of the Handbook are briefly introduced to provide an overview of its past evolution and future prospects. Detailed instructions are given with examples for navigating the constructed Handbook components and using the main functionalities. Procedures are provided in a step-by-step fashion for Data Upload Managers to upload reports and data files, as well as for new users to initiate Handbook access.

  16. Stable kagome lattices from group IV elements

    Science.gov (United States)

    Leenaerts, O.; Schoeters, B.; Partoens, B.

    2015-03-01

    A thorough investigation of three-dimensional kagome lattices of group IV elements is performed with first-principles calculations. The investigated kagome lattices of silicon and germanium are found to be of similar stability as the recently proposed carbon kagome lattice. Carbon and silicon kagome lattices are both direct-gap semiconductors but they have qualitatively different electronic band structures. While direct optical transitions between the valence and conduction bands are allowed in the carbon case, no such transitions can be observed for silicon. The kagome lattice of germanium exhibits semimetallic behavior but can be transformed into a semiconductor after compression.

  17. Dual (type IV left anterior descending artery

    Directory of Open Access Journals (Sweden)

    Ozdil Baskan

    2013-11-01

    Full Text Available Congenital coronary artery anomalies are uncommon. Dual left anterior descending coronary artery (LAD is defined as the presence of two LADs within the anterior interventricular sulcus (AIVS, and is classified into four types. Type IV is a rarely reported subtype and differs from the others, with a long LAD originating from the right coronary artery (RCA. Dual LAD is a benign coronary artery anomaly, but should be recognised especially before interventional procedures. With the increasing use of multidedector computed tomography (MDCT, it is essential for radiologists to be aware of this entity and the cross-sectional findings.

  18. Benzylchloridobis(quinolin-8-olatotin(IV

    Directory of Open Access Journals (Sweden)

    Qibao Wang

    2009-08-01

    Full Text Available In the title compound, [Sn(C7H7(C9H6NO2Cl], the SnIV ion is in a distorted octahedral coordination environment formed by the O and N atoms of two bis-chelating quinolin-8-olate ligands, a Cl atom and a C atom from a benzyl ligand. The axial sites are occupied by an N atom of a quinolinate ligand and the C atom of the benzyl ligand. The axial Sn—N bond is slightly shorter than the equatorial Sn—N bond.

  19. Resgate vegetativo por alporquia de genótipos adultos de urucum (Bixa orellana L.

    Directory of Open Access Journals (Sweden)

    Nilton César Mantovani

    2010-09-01

    Full Text Available Este trabalho teve por objetivos avaliar a técnica de alporquia visando ao resgate vegetativo de genótipos de urucum (Bixa orellana L. e a obtenção de plantas fornecedoras de propágulos para processos de propagação clonal. Foram utilizadas dez plantas matrizes de urucum, com 12 anos de idade, obtidas partindo do cruzamento artificial entre os genótipos "Fruto Verde Piloso" X "Fruto Vermelho Liso". Os alporques foram realizados em ramos de 1 a 2 cm de diâmetro, utilizando-se como substrato uma mistura de vermiculita e musgo. Foi avaliado o efeito (1 do tipo de anelamento da casca dos ramos (total ou parcial, com 1 cm de comprimento, (2 do AIB (ácido indol-3-butírico a 0 e 4,92 mM aplicado em papel filtro e (3 do tipo de proteção dos alporques (filmes plásticos transparente ou preto ou tecido tencel, no enraizamento de alporque dos dez genótipos. A técnica de alporquia proporcionou o enraizamento de ramos dos dez genótipos avaliados, com eficiência variável de 20 a 100%, havendo efeito do genótipo sobre a frequência de enraizamento. A sobrevivência desses alporques foi de 100% após o plantio quando estes foram produzidos com anelamento total, tratados com AIB e protegidos com plástico transparente. Em casa de vegetação os alporques desenvolveram ramos partindo da brotação de gemas caulinares constituindo estoques de explantes apropriados para serem utilizados como estacas ou como fontes de segmentos nodais para a propagação in vitro desta espécie.

  20. Predicting DPP-IV inhibitors with machine learning approaches

    Science.gov (United States)

    Cai, Jie; Li, Chanjuan; Liu, Zhihong; Du, Jiewen; Ye, Jiming; Gu, Qiong; Xu, Jun

    2017-02-01

    Dipeptidyl peptidase IV (DPP-IV) is a promising Type 2 diabetes mellitus (T2DM) drug target. DPP-IV inhibitors prolong the action of glucagon-like peptide-1 (GLP-1) and gastric inhibitory peptide (GIP), improve glucose homeostasis without weight gain, edema, and hypoglycemia. However, the marketed DPP-IV inhibitors have adverse effects such as nasopharyngitis, headache, nausea, hypersensitivity, skin reactions and pancreatitis. Therefore, it is still expected for novel DPP-IV inhibitors with minimal adverse effects. The scaffolds of existing DPP-IV inhibitors are structurally diversified. This makes it difficult to build virtual screening models based upon the known DPP-IV inhibitor libraries using conventional QSAR approaches. In this paper, we report a new strategy to predict DPP-IV inhibitors with machine learning approaches involving naïve Bayesian (NB) and recursive partitioning (RP) methods. We built 247 machine learning models based on 1307 known DPP-IV inhibitors with optimized molecular properties and topological fingerprints as descriptors. The overall predictive accuracies of the optimized models were greater than 80%. An external test set, composed of 65 recently reported compounds, was employed to validate the optimized models. The results demonstrated that both NB and RP models have a good predictive ability based on different combinations of descriptors. Twenty "good" and twenty "bad" structural fragments for DPP-IV inhibitors can also be derived from these models for inspiring the new DPP-IV inhibitor scaffold design.

  1. Competitividade de biótipos de capim-arroz resistente e suscetível ao quinclorac Competitiveness of echinochloa biotypes resistant and susceptible to quinclorac

    Directory of Open Access Journals (Sweden)

    G. Concenço

    2008-03-01

    Full Text Available Objetivou-se com este trabalho avaliar a competitividade de dois biótipos de capim-arroz, resistente e suscetível ao quinclorac, coletados em regiões orizícolas do Estado de Santa Catarina. O experimento foi instalado em ambiente protegido, e os tratamentos constaram de diferentes densidades de plantas dos biótipos de capim-arroz comprovadamente resistente (ITJ-13 e suscetível (ITJ-17 ao quinclorac, oriundos da região arrozeira de Itajaí/SC. No centro da unidade experimental, foram semeadas três sementes do biótipo de capim-arroz, considerado como o tratamento da unidade experimental. Na periferia foram semeadas dez sementes do biótipo oposto ao do tratamento (central. Dez dias após a germinação foi efetuado o desbaste, deixando-se apenas uma planta no centro da unidade experimental e um número variável de plantas do biótipo oposto, de acordo com o tratamento (0, 1, 2, 3, 4 ou 5 plantas por vaso. O delineamento experimental utilizado foi o completamente casualizado, em esquema fatorial 2 x 6, com quatro repetições. Aos 40 dias após a emergência, foram avaliados altura de plantas, número de afilhos e de folhas, área foliar, massa fresca e seca e conteúdo de água de colmos e folhas. Os dados foram analisados pelo teste F, sendo efetuado teste de Duncan para comparar o efeito de densidade de plantas e teste da Diferença Mínima Significativa (DMS para avaliar diferenças entre os biótipos resistente e suscetível, além de correlação linear simples entre as variáveis avaliadas. Nas análises, utilizou-se o nível de 5% de probabilidade. Os biótipos estudados de capim-arroz resistente e suscetível ao quinclorac são similares quando sob alta intensidade de competição, com vantagem em algumas variáveis para o biótipo suscetível sob baixa ou moderada intensidade competitiva.The objective of this research was to evaluate the competitive potential of two Echinochloa sp. biotypes, resistant and susceptible to

  2. Estimando un Modelo de 2 Factores del Tipo

    Directory of Open Access Journals (Sweden)

    Sergio Zuñiga

    1999-03-01

    Full Text Available In this article we estimate a two-factor model for the risk-free term structure yield in Chile. These factors are the short rate and the central tendency that are not directly estimable. Both factors follow an Ito stochastic process. In the solution of the model we follow the Balduzzi et al. (1996 specification, which provides an estimation procedure that do not depend on the parametric specification of the second factor and an "exponential affine" solution type that allows to estimate the model by mean of only one equation. The data used in this study is the average weekly yields of the bonds "Bonos de Reconocimiento" (BR of the Chilean stock exchange during May 1993 and December 1997. The results show that when we use a stochastic level for the long term rates the yields adjust better than the case when this level is constant. Also, the speed of the reversion process increases due to the better performance of the short term rate. In addition, using an ARCH specification for the rate volatility we found additional evidence that the variance of the rates. In this article we estimate a two-factor model for the risk-free term structure yield in Chile. These factors are the short rate and the central tendency that are not directly estimable. Both factors follow an Ito stochastic process. In the solution of the model we follow the Balduzzi et al. (1996 specification, which provides an estimation procedure that do not depend on the parametric specification of the second factor and an "exponential affine" solution type that allows to estimate the model by mean of only one equation. The data used in this study is the average weekly yields of the bonds "Bonos de Reconocimiento" (BR of the Chilean stock exchange during May 1993 and December 1997. The results show that when we use a stochastic level for the long term rates the yields adjust better than the case when this level is constant. Also, the speed of the reversion process increases due to the

  3. Correlacionando tipos de cultura organizacional com estratégias de remuneração utilizando a tipologia de Charles Handy Correlation between organizational culture and compensation strategies using Charles Handy's typology

    Directory of Open Access Journals (Sweden)

    Giuseppe Maria Russo

    2012-12-01

    Full Text Available Este estudo identificou as correlações entre as estratégias de remuneração e a tipologia de cultura organizacional proposta por Handy (2003 baseada nas dimensões do grau de formalização e centralização que identifica a cultura: Zeus (poder, Apolo (papéis, Atena (tarefa, e Dionísio (pessoa. A pesquisa foi aplicada a gestores de remuneração de 76 empresas associadas ao Grupo de Permuta de Informações Salariais (Grupisa, e os questionários com um construto composto por doze componentes da remuneração organizacional foram analisados utilizando Correlação de Pearson e Regressão Múltipla. Concluímos que as variáveis de remuneração se correlacionam de forma diferente com cada um dos tipos de cultura: (i organizações "Zeus" devem enfatizar os fatores comportamentais em todas as esferas do sistema de remuneração; (ii para as organizações "Apolo" a ênfase deve ser aplicada nas oportunidades de crescimento e desenvolvimento, (iii nas organizações "Atena" o foco deve ser nas recompensas financeiras, e, (iv organizações "Dionísio" devem dar ênfase à qualidade da remuneração.This study identified the correlations between compensation strategies and the organizational culture typology proposed by Handy (2003, based on the degree of formalization and centralization that identifies the culture: Zeus (power, Apollo (roles, Athena (task and Dionysus (person. A survey was performed of compensation managers at 76 companies associated with the Salary Information Exchange Group (GRUPISA, and the questionnaires with a construct composed of twelve organizational compensation components were analyzed using Pearson's correlation coefficient and multiple regression We concluded that the compensation variables were correlated in a different fashion with each of the culture types: (i "Zeus" organizations should emphasize behavioral factors in all spheres of the compensation system; (ii in the case of "Apollo" organizations the

  4. Correcting C IV-based virial black hole masses

    Science.gov (United States)

    Coatman, Liam; Hewett, Paul C.; Banerji, Manda; Richards, Gordon T.; Hennawi, Joseph F.; Prochaska, J. Xavier

    2017-02-01

    The C IVλλ1498,1501 broad emission line is visible in optical spectra to redshifts exceeding z ˜ 5. C IV has long been known to exhibit significant displacements to the blue and these `blueshifts' almost certainly signal the presence of strong outflows. As a consequence, single-epoch virial black hole (BH) mass estimates derived from C IV velocity widths are known to be systematically biased compared to masses from the hydrogen Balmer lines. Using a large sample of 230 high-luminosity (LBol = 1045.5-1048 erg s-1), redshift 1.5 < z < 4.0 quasars with both C IV and Balmer line spectra, we have quantified the bias in C IV BH masses as a function of the C IV blueshift. C IV BH masses are shown to be a factor of 5 larger than the corresponding Balmer-line masses at C IV blueshifts of 3000 km s-1and are overestimated by almost an order of magnitude at the most extreme blueshifts, ≳5000 km s-1. Using the monotonically increasing relationship between the C IV blueshift and the mass ratio BH(C IV)/BH(Hα), we derive an empirical correction to all C IV BH masses. The scatter between the corrected C IV masses and the Balmer masses is 0.24 dex at low C IV blueshifts (˜0 km s-1) and just 0.10 dex at high blueshifts (˜3000 km s-1), compared to 0.40 dex before the correction. The correction depends only on the C IV line properties - i.e. full width at half-maximum and blueshift - and can therefore be applied to all quasars where C IV emission line properties have been measured, enabling the derivation of unbiased virial BH-mass estimates for the majority of high-luminosity, high-redshift, spectroscopically confirmed quasars in the literature.

  5. Sistema de almacenamiento de energía eléctrica en central de ciclo combinado

    OpenAIRE

    Saez Muñiz, Javier

    2016-01-01

    El presente Proyecto Final de Carrera estudia la implantación de un sistema de almacenamiento de energía eléctrica, adecuado para la instalación en una Central Eléctrica de Ciclo Combinado. Así mismo, su estructura podrá ser aplicable a otros tipos de centrales eléctricas, industrias, o instalaciones con mínimas modificaciones. El objeto incluye el estudio, cálculo y diseño del sistema de almacenamiento de energía, evaluando diferentes tipos de tecnologías existentes en la actu...

  6. Estudio epidemiológico, morfológico y microbiológico de la isquemia crónica de miembros inferiores estadio IV

    OpenAIRE

    2013-01-01

    Objetivos: Evaluar en pacientes con diagnóstico de isquemia crónica de miembros inferiores estadio IV las características epidemiológicas, los factores pronósticos que influyen en el desarrollo de la enfermedad y en el resultado final del proceso (amputación menor, amputación mayor e isquemia crónica no revascularizable). Comparar su evolución, en función del tipo de lesión isquémica y determinar qué factores han influido en el desarrollo de la enfermedad y las complicaciones durante su estan...

  7. Tetrachlorido[(diphenylphosphinodiphenylphosphine oxide-κO]zirconium(IV benzene monosolvate

    Directory of Open Access Journals (Sweden)

    Takahiko Ogawa

    2009-09-01

    Full Text Available In the title centrosymmetric mononuclear ZrIV compound, [ZrCl4{P(O(C6H52P(C6H52}2]·C6H6, the central ZrIV ion is coordinated by two O atoms from two symmetry-related (diphenylphosphinodiphenylphosphine ligands and four Cl atoms in a distorted octahedral geometry with the four Cl atoms in the equatorial positions. The molecule lies about a center of inversion and the benzene solvent molecule about another center of inversion. The P=O bond [1.528 (2 Å] is slightly longer than a typical P=O double bond (average 1.500 .

  8. Autoinmunidad y receptores tipo Toll = Autoimmunity and toll-like receptors

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    Ossa Giraldo, Ana Claudia

    2012-07-01

    Full Text Available La respuesta inmune innata está conformada por un conjunto de mecanismos que permiten reconocer los componentes propios del organismo y diferenciarlos de los microorganismos invasores para generar una primera línea de defensa. Este reconocimiento está mediado por diferentes receptores presentes en la superficie y en el interior de células inmunes y no inmunes; entre ellos se encuentran los siguientes: receptores tipo Toll (RTT, receptores de lectinas tipo C, receptores tipo GIR (genes inducibles por ácido retinoico y receptores tipo Nod y NALP, que reconocen patrones moleculares asociados a microorganismos (PMAM. Gracias a esta capacidad de discriminación, adquirida evolutivamente por la inmunidad innata, se ha aceptado tradicionalmente que los procesos autoinmunes no están relacionados con esta sino con la inmunidad adquirida. Sin embargo, varios estudios han demostrado que esa teoría no es totalmente cierta y que algunos mecanismos efectores de la inmunidad innata participan en la generación de las enfermedades autoinmunes o en la potenciación de su fisiopatología. En esta revisión se estudia la contribución de la inmunidad innata a la autoinmunidad con énfasis en el papel de los receptores tipo Toll.

  9. Synthesis and characterization of thorium(IV) and uranium(IV) corrole complexes.

    Science.gov (United States)

    Ward, Ashleigh L; Buckley, Heather L; Lukens, Wayne W; Arnold, John

    2013-09-18

    The first examples of actinide complexes incorporating corrole ligands are presented. Thorium(IV) and uranium(IV) macrocycles of Mes2(p-OMePh)corrole were synthesized via salt metathesis with the corresponding lithium corrole in remarkably high yields (93% and 83%, respectively). Characterization by single-crystal X-ray diffraction revealed both complexes to be dimeric, having two metal centers bridged via bis(μ-chlorido) linkages. In each case, the corrole ring showed a large distortion from planarity, with the Th(IV) and U(IV) ions residing unusually far (1.403 and 1.330 Å, respectively) from the N4 plane of the ligand. (1)H NMR spectroscopy of both the Th and U dimers revealed dynamic solution behavior. In the case of the diamagnetic thorium corrole, variable-temperature, DOSY (diffusion-ordered) and EXSY (exhange) (1)H NMR spectroscopy was employed and supported that this behavior was due to an intrinsic pseudorotational mode of the corrole ring about the M-M axis. Additionally, the electronic structure of the actinide corroles was assessed using UV-vis spectroscopy, cyclic voltammetry, and variable-temperature magnetic susceptibility. This novel class of macrocyclic complexes provides a rich platform in an underdeveloped area for the study of nonaqueous actinide bonding and reactivity.

  10. The Design of the IGE Evaluation Project Phase IV Comparative Studies. Comparative Study of Phase IV IGE Evaluation Project. Phase IV, Project Paper 80-2.

    Science.gov (United States)

    Romberg, Thomas A.; And Others

    This paper outlines the design of two Comparative Studies of Phase IV of the Individually Guided Education (IGE) Evaluation Project. More than 2,000 elementary schools in 25 states use the IGE system. The Evaluation Project was designed to gain a comprehensive view of the system's operation and effectiveness. Phase IV investigated pupil outcomes,…

  11. Plutón La Costa, una expresión de magmatismo tipo-s en el sector noreste de la Sierra de Velasco, Sierras Pampeanas

    Directory of Open Access Journals (Sweden)

    P.H. Alasino

    2006-06-01

    Full Text Available Estudios combinados de petrología, química mineral y geoquímcia de roca total revelan la presencia de dos unidades graníticas peraluminosas con minerales aluminosos magmáticos tales como granate y mica blanca y la presencia distintiva de turmalina. Las evidencias aquí presentadas indican que estas dos facies, Anillaco y Anjullón, junto a la unidad peraluminosa Santa Cruz estudiada en trabajos previos, constituyen una serie de rocas co-sanguíneas, emplazadas en niveles someros de la corteza y las cuales conforman una unidad ígnea mayor denominada aquí plutón La Costa, la cual aflora en el sector noreste de la sierra de Velasco. La asociación mineral, la química mineral y la geoquímica de roca total permiten definir al plutón La Costa como un clásico granitoide tipo-S, derivado de una roca fuente de composición esencialmente pelítica. Diferentes estudios demuestran que la generación de granitoides tipo-S requiere de un alto gradiente geotérmico, por lo cual el plutón La Costa indica que la corteza en esta región soportó un notable calentamiento durante la generación del magma. Sin embargo, la ausencia de datos geocronológicos impide definir el evento tectomagmático que produjo el magma primordial de este plutón.

  12. Clonal types and antimicrobial resistance profiles of methicillin-resistant Staphylococcus aureus isolates from hospitals in south Brazil Tipos de clones e perfis de resistência antimicrobiana de Staphylococcus aureus resistentes à meticilina isolados de hospitais no sul do Brasil

    Directory of Open Access Journals (Sweden)

    Leandro Reus Rodrigues Perez

    2008-06-01

    Full Text Available In the present study were evaluated the DNA macrorestriction profile and SCCmec types for nine multi-resistant MRSA selected. Also antimicrobial susceptibility testing by disk diffusion method was evaluated for 68 MRSA isolates against 12 antimicrobial agents. The isolates were recovered from blood culture collected from hospitalized patients in three hospitals of Porto Alegre, Brazil. PFGE and PCR for mecA and SCCmec I, II, III, IV types genes were done on selected nine isolates with susceptibility only to vancomycin, teicoplanin and linezolid. Two clone profiles, with five subtypes, were demonstrated among multi-resistant MRSA analyzed. Eight isolates showed harbor SCCmec type III and one isolate was not typeable. The knowledge of SCCmec type, clone and antimicrobial profiles among S. aureus is essential mainly to prevention and control of dissemination of the antimicrobial resistance.No presente estudo foram avaliados o perfil de macrorrestrição do DNA e tipos de SCCmec para nove MRSA multirresistentes selecionados. Além disso, susceptibilidade a 12 agentes antimicrobianos pelo teste de disco-difusão foi avaliada para 68 isolados de MRSA. Os isolados foram obtidos de hemoculturas de pacientes hospitalizados de três hospitais de Porto Alegre, Brasil. PFGE e PCR para detecção do gene mecA e para os tipos genéticos SCCmec I, II, III e IV foram realizados em nove isolados selecionados que apresentaram susceptibilidade somente a vancomicina, teicoplanina e linezolida. Dois perfis clonais, com cinco subtipos, foram demonstrados entre os isolados analisados. Oito isolados apresentaram SCCmec tipo III e um isolado não foi caracterizado quanto ao tipo de SCCmec. O conhecimento do tipo de SCCmec bem como dos perfis clonais e de susceptibilidade aos antimicrobianos entre isolados de S. aureus é essencial, principalmente, para a prevenção e controle da disseminação da resistência antimicrobiana.

  13. Implementation of GLP-1 based therapy of type 2 diabetes mellitus using DPP-IV inhibitors.

    Science.gov (United States)

    Holst, Jens Juul

    2003-01-01

    GLP-1 is a peptide hormone from the intestinal mucosa. It is secreted in response to meal ingestion and normally functions in the so-called ileal brake i. e. inhibition of upper gastrointestinal motility and secretion when nutrients are present in the distal small intestine. It also induces satiety and promotes tissue deposition of ingested glucose by stimulating insulin secretion. Thus, it is an essential incretin hormone. In addition, the hormone has been demonstrated to promote insulin biosynthesis and insulin gene expression and to have trophic effects on the beta cells. The trophic effects include proliferation of existing beta cells, maturation of new cells from duct progenitor cells and inhibition of apoptosis. Furthermore glucagon secretion is inhibited. Because of these effects, the hormone effectively improves metabolism in patients with type 2 diabetes mellitus. However, continuous administration of the peptide is necessary because of an exceptionally rapid rate of degradation catalyzed the enzyme dipeptidyl peptidase IV. With inhibitors of this enzyme, it is possible to protect the endogenous hormone and thereby elevate both fasting and postprandial levels of the active hormone. This leads to enhanced insulin secretion and glucose turnover. But will DPP-IV inhibition enhance all effects of the endogenous peptide? The mode of action of GLP-1 is complex involving also interactions with sensory neurons and the central nervous system, where a DPP-IV mediated degradation does not seem to occur. Therefore, it is as yet uncertain wether DDP-IV inhibitors will affect gastrointestinal motility, appetite and food intake. Even the effects of GLP-1 effects on the pancreatic islets may be partly neurally mediated and therefore uninfluenced by DPP-IV inhibition.

  14. Tipos y uso de argumentos escépticos en Hume

    Directory of Open Access Journals (Sweden)

    Plínio Junqueira Smith

    2010-12-01

    Full Text Available La intención del presente artículo es mostrar que Hume distingue dos tipos de argumentos escépticos. El tipo antiguo, basado en el método de antinomias, es considerado muy débil por Hume. Él desarrolla un tipo nuevo de argumento escéptico a partir de su ciencia empírica de la naturaleza humana. Del otro lado, Hume distingue entre dos usos de los argumentos escépticos: el primero, que él llama pirrónico, tiene como finalidad la suspensión del juicio, lo que es imposible, porque la naturaleza nos obliga a creer; el segundo, el uso académico, pone límites a nuestro conocimiento, aceptando las creencias naturales, la ciencia empírica y las matemáticas.

  15. Neurinoma central do nervo acústico

    Directory of Open Access Journals (Sweden)

    Paulo Pinto Pupo

    1950-03-01

    Full Text Available O autor apresenta o caso de uma paciente com 45 anos, com hipertensão arterial, queixando-se de tonturas e surdez progressiva à esquerda que, ao exame neurológico, apresentava síndrome protuberancial, com hemi-anestesia táctil e dolorosa à direita respeitando a face, hemiparesia direita, ataxia de tipo sensitivo nos membros da direita, paralisia facial de tipo periférico, hipoacusia, paresia de motor ocular externo à esquerda, síndrome vertiginosa e nistagmo horizontal ao olhar para a direita. À necrópsia foi encontrado um tumor na hemicalota protuberancial esquerda e foco malácico adjacente, secundário a distúrbio circulatório. O tumor, intimamente dependente das raízes intraprotuberanciais do nervo acústico, se apresentava com as características histológicas dos neurinomas. Além dessas particularidades, a lesão do feixe central da calota e conseqüente degeneração "hipertrófica" da oliva bulbar constituem outro aspecto de grande interêsse dêste caso.

  16. Activity monitoring reflects cardiovascular and metabolic variations in COPD patients across GOLD stages II to IV.

    Science.gov (United States)

    Kortianou, E A; Louvaris, Z; Vasilopoulou, M; Nasis, I; Kaltsakas, G; Koulouris, N G; Vogiatzis, I

    2013-12-01

    We investigated whether activity monitoring reliably reflects variations in oxygen transport and utilization during walking in COPD patients. Forty-two patients (14 in each GOLD stage II, III and IV) performed an incremental treadmill protocol to the limit of tolerance. Breath-by-breath gas exchange, central hemodynamic variables and activity monitoring were simultaneously recorded. Physiological variables and accelerometer outputs rose linearly with walking speeds. Strong correlations (r[interquartile range, IQR]) were found between treadmill walking intensity (WI: range 0.8-2.0 ms(-2)) and oxygen consumption (0.95 [IQR 0.87-0.97]), (range 7.6-15.5 ml kg(-1)min(-1)); minute ventilation (0.95 [IQR 0.86-0.98]), (range 20-37 l min(-1)); cardiac output (0.89 [IQR 0.73-0.94]), (range 6.8-11.5 l min(-1)) and arteriovenous oxygen concentration difference (0.84 [IQR 0.76-0.90]), (range 7.7-12.1 ml O2100 ml(-1)). Correlations between WI and gas exchange or central hemodynamic parameters were not different across GOLD stages. In conclusion, central hemodynamic, respiratory and muscle metabolic variations during incremental treadmill exercise are tightly associated to changes in walking intensity as recorded by accelerometry across GOLD stages II to IV. Interestingly, the magnitude of these associations is not different across GOLD stages.

  17. Carpentier, la otra novela (cap. IV

    Directory of Open Access Journals (Sweden)

    Urbano Martínez Carmenate

    2014-06-01

    Full Text Available El presente ensayo está extraído de la obra inédita de Urbano Martínez Carmenate, Carpentier, la otra novela (cap. IV. Ofrece una mirada sobre los primeros años de la trayectoria profesional de Alejo Carpentier. Se muestra cómo, durante la década de 1920, se inicia como periodista y cronista teatral. A la vez, comienzan sus conexiones con el Grupo Minorista, que desempeña un papel destacado en la etapa republicana en Cuba. También se contempla su viaje a México en 1926, que constituye su primer contacto directo con la naturaleza y la cultura americanas.

  18. Carpentier, la otra novela (cap. IV

    Directory of Open Access Journals (Sweden)

    Urbano Martínez Carmenate

    2014-07-01

    Full Text Available El presente ensayo está extraído de la obra inédita de Urbano Martínez Carmenate, Carpentier, la otra novela (cap. IV. Ofrece una mirada sobre los primeros años de la trayectoria profesional de Alejo Carpentier. Se muestra cómo, durante la década de 1920, se inicia como periodista y cronista teatral. A la vez, comienzan sus conexiones con el Grupo Minorista, que desempeña un papel destacado en la etapa republicana en Cuba. También se contempla su viaje a México en 1926, que constituye su primer contacto directo con la naturaleza y la cultura americanas.

  19. [Vaughan Williams class IV antiarrhythmic drugs].

    Science.gov (United States)

    Horie, M; Washizuka, T; Ikeguchi, S; Sasayama, S

    1996-08-01

    Vaughan Williams class IV antiarrhythmic drugs have Ca-channel blocking actions. Since L-type Ca-channels play key roles in regulating pulse conduction in atrioventricular node as well as in pathologically-depolarized myocardium, Ca-channel blockers known to modulate this type of Ca-channel (ICa,L) are used as antiarrhythmic agents. ICa,L channels have relatively high threshold potential (-40 mV) to activate and long-opening properties, and are enhanced by beta-adrenergic stimulation. Among three major ICa,L blockers, dihydropyridines such as nifedipine were found to bind to the channel from extracellular side. In contrast, verapamil and diltiazem interact with the channel from the cytoplasmic side, thereby causing rate-dependent block of ICa,L channels. This sideness of pharmacological action of the Ca-channel blockers determines an important therapeutic modality and their indication for tachyarrhythmias.

  20. Attitudes of Major Soviet Nationalities. Volume IV. Central Asia. Kazakhstan, Kirgizistan, Turkmenistan, Uzbekistan, Tadzhikistan.

    Science.gov (United States)

    1973-06-01

    following chapters: KAZAKHSTAN-AND THE KAZAKHS - Zev Katz KIRGIZISTAN AND THE KIRGIZ - Allen Hetmanek TURKMENISTAN’AND THE TURKMEN - A. Berdi Murat ...8217 0 co L Ln (N L -4 -4j 0 0 -40 co 0’ 0) 𔃺 6’D 00 00 0 H "- 0 0 ’. . 󈧜 CA4 04 (N 41 d.J 04. 0) U 0 0 0W ,4 ( LA -. cn ULA -n LA r- 07% 0 *ja 0 L 00...TURKMEN prepared by A. Berdi Murat Columbia Universi ty This chapter is based on a paper contributed by the above-named specialist. However, the chapter

  1. New mono-organotin (IV) dithiocarbamate complexes

    Science.gov (United States)

    Muthalib, Amirah Faizah Abdul; Baba, Ibrahim

    2014-09-01

    Eighteen new mono-organotin dithiocarbamate compounds derived each nine from methyltin(IV) and phenyltin(IV) reacted using in-situ method with various type of N-dialkylamine together with carbon disulphide with the ratio of 1:3:3. Elemental and gravimetric analysis showed that the general formula of these compounds were RSnCl[S2CNR'R″]2 (R= Ph, CH3, R' = CH3, C2H5, C7H7 and R″ = C2H5, C6H11, iC3H7, C7H7). These compounds had been characterized by infrared spectroscopy, ultraviolet spectroscopy, 1H, 13C NMR spectroscopy and single crystal X-ray crystallography. The infrared spectra of these compounds showed three important peaks indicating the formation of dithiocarbamate compounds, ν(CN), ν(CS) and ν(Sn-S) band which present in the region of 1444-1519, 954-1098 and 318-349 cm-1 respectively. The ultraviolet-visible spectra showed an absorption band for the π - π* transition of NCS group in the range of 253 - 259 nm due to the intramolecular charge transfer of the ligand. The 13C NMR spectra showed an important shift for δ(N13CS2) in the range of 196.8 - 201.9 ppm.. Single crystal X-ray diffraction studies showed three new structures with the general formula of PhSnCl[S2CN(Et)(i-Pr)]2, MeSnCl[S2CN(Me)(Cy)]2 and MeSnCl[S2CN(i-Pr)(CH2Ph)]2. All structures having a distorted octahedral geometry set by CClS4 donor atom from the two chelating dithiocarbamate ligands.

  2. Síndrome metabólica, resistência à ação da insulina e doença cardiovascular no diabete melito tipo 1 Síndrome metabólico, resistencia a la acción de la insulina y enfermedad cardiovascular en la diabetes mellitus tipo 1 Metabolic syndrome, insulin resistance and cardiovascular disease in type-1 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Ticiana C. Rodrigues

    2010-01-01

    Full Text Available A síndrome metabólica (SM é um transtorno complexo representado por um conjunto de fatores de risco cardiovasculares relacionados à deposição central de gordura e à resistência à ação da insulina (RI, e está associada à mortalidade precoce em indivíduos não-diabéticos e em pacientes com Diabete melito (DM tipo 2. A presença da SM e dos seus componentes tem sido descrita também em pacientes com DM tipo 1 e pode contribuir para o elevado risco de doença cardiovascular observado nessa população de pacientes. O objetivo deste trabalho foi revisar as evidências disponíveis sobre o papel da SM e da RI no desenvolvimento da doença cardiovascular nos pacientes com DM tipo 1.El síndrome metabólico (SM es un trastorno complejo representado por un conjunto de factores de riesgo cardiovasculares relacionados al depósito central de grasa y a la resistencia a la acción de la insulina (RI, y se asocia a mortalidad precoz en individuos no diabéticos y en pacientes con diabetes mellitus (DM tipo 2. La presencia del SM y sus componentes viene siendo descripta también en pacientes con DM tipo 1 y puede contribuir al elevado riesgo de enfermedad cardiovascular observado en esta población de pacientes. El objetivo de este trabajo fue revisar las evidencias disponibles sobre el papel del SM y de la RI en el desarrollo de la enfermedad cardiovascular en los pacientes con DM tipo 1.Metabolic syndrome (MS is a complex disorder represented by a cluster of cardiovascular risk factors related to central fat distribution and insulin resistance (IR, and is associated with early mortality in non-diabetic individuals and in patients with type-2 diabetes mellitus (DM. The presence of MS and its components has also been described in patients with type-1 DM and may contribute to the increased risk of cardiovascular disease seen in this patient population. The objective of this study was to review the available evidences of the role of MS and IR in

  3. Comercio, tipo de cambio real y crecimiento económico

    OpenAIRE

    Enrique R. Casares.

    2007-01-01

    Se desarrolla un modelo de crecimiento endógeno con tres bienes, exportable, importado y no-comerciable. Se estudia la respuesta del tipo de cambio real y de la tasa de crecimiento de la economía a una disminución de la tasa arancelaria. Se muestra que una liberalización comercial debe ir acompañada de una depreciación del tipo de cambio real. Se deduce que la tasa de crecimiento de la economía se incrementa en el largo plazo. Se argumenta que la economía mexicana no siguió este comportamient...

  4. Diabetes Tipo 2 y Depresión en Guadalajara, México. 2005

    OpenAIRE

    Colunga-Rodríguez, Cecilia; García de Alba, Javier E.; José G. Salazar-Estrada; Ángel-González, Mario

    2008-01-01

    Objetivo Determinar la prevalencia de depresión y comparar indicadores sociodemográficos, metabólicos y clínicos, en personas con diabetes tipo 2 deprimidas y no deprimidas. Material y métodos Se realizó un estudio transversal comparativo en una muestra de 450 personas con diabetes tipo 2, mayores de 30 años, con más de un año de diagnóstico y sin determinación de psicopatología. Aplicamos escala de Zung modificada y encuesta sociodemográfica, evaluamos Hemoglobina glucosilada, índice de masa...

  5. Percepción de la insulinoterapia en pacientes con diabetes mellitus tipo 2 descontrolada

    OpenAIRE

    Rafael Leyva Jiménez; Gustavo Hernández Zambrano; Silvia Ibarra Maldonado; Carlos Tomás Ibarra Ramírez

    2016-01-01

    Objetivo: Conocer la percepción de la insulinoterapia en los pacientes con diabetes mellitus tipo 2 descontrolada tratados con hipoglucemiantes orales o con insulina. Diseño: Transversal comparativo prospectivo. Emplazamiento: Unidad de Medicina Familiar número 53 de la Delegación Guanajuato del Instituto Mexicano del Seguro Social. Participantes: Pacientes de 40 a 80 años afectos de diabetes tipo 2, descontrolados, en tratamiento con insulina o hipoglucemiantes orales. Mediciones...

  6. Manifestaciones orales en pacientes diabéticos tipo 2 y no diabéticos.

    OpenAIRE

    Rafaela del Toro Ávalos; María Guadalupe Aldrete Rodríguez; Álvaro Cruz González; Víctor Manuel Ramírez Anguiano; Patricia Lorelei Mendoza Roaf; José Luis Vázquez Castellanos; Carlos E. Bracamontes Campoy

    2004-01-01

    El propósito de esta investigación fue analizar el estado de higiene bucal, caries, enfermedad periodontal, presencia de candidiasis e infección post-extracción en pacientes diabéticos tipo 2 en comparación con pacientes no diabéticos. De 226 pacientes, 180 eran no diabéticos y 46 diabéticos tipo 2, todos con resultados recientes de hemoglobina glucosilada y glicemia. Se les realizó un examen clínico evaluando el índice de higiene bucal simplificado, dientes cariados, la presencia de candidia...

  7. La transformación de los tipos residenciales tradicionales como motor del proyecto de arquitectura

    OpenAIRE

    Abaurre Delgado, Blanca

    2015-01-01

    El trabajo realizado ha consistido en el análisis de los tipos arquitectónicos básicos de la construcción de la ciudad histórica de Sevilla, Casas Patio, Corrales de Vecinos y la Casa Vecinal, para estudiar como esos tipos pueden construir unas bases, mediante su concepción como estructura espacial, y ser utilizadas como material para la concepción de la arquitectura contemporánea de la ciudad. Grado en Fundamentos de Arquitectura

  8. EVIDENCIA DE UN TIPO INVESTIGACIÓN QUE ABORDE DE MILES Y SNOW EN BRASIL

    OpenAIRE

    Vanderlei Vieira; Roberto Klosowski Machado; Nathanael Kusch Brey; Carlos Ricardo Rossetto

    2012-01-01

    El objetivo de este trabajo es analizar las referencias utilizadas en las publicaciones de las conferencias nacionales que las tipologías actuales de gestión desarrolladas por Miles y Snow. El método utilizado en el estudio fue de tipo descriptivo, con abordaje cuantitativo, y el estudio bibliométrico tipo. En la selección de artículos, se tomó como base la existencia del término "Miles y Snow" en el título, resumen o palabras clave, la observación de la literatura mencionada en los artículos...

  9. Prenatal IV Cocaine: Alterations in Auditory Information Processing

    Directory of Open Access Journals (Sweden)

    Charles F. Mactutus

    2011-06-01

    Full Text Available One clue regarding the basis of cocaine-induced deficits in attentional processing is provided by the clinical findings of changes in the infants’ startle response; observations buttressed by neurophysiological evidence of alterations in brainstem transmission time. Using the IV route of administration and doses that mimic the peak arterial levels of cocaine use in humans, the present study examined the effects of prenatal cocaine on auditory information processing via tests of the acoustic startle response (ASR, habituation, and prepulse inhibition (PPI in the offspring. Nulliparous Long-Evans female rats, implanted with an IV access port prior to breeding, were administered saline, 0.5, 1.0, or 3.0 mg/kg/injection of cocaine HCL (COC from gestation day (GD8-20 (1x/day-GD8-14, 2x/day-GD15-20. COC had no significant effects on maternal/litter parameters or growth of the offspring. At 18-20 days of age, one male and one female, randomly selected from each litter displayed an increased ASR (>30% for males at 1.0 mg/kg and >30% for females at 3.0 mg/kg. When reassessed in adulthood (D90-100, a linear dose-response increase was noted on response amplitude. At both test ages, within-session habituation was retarded by prenatal cocaine treatment. Testing the females in diestrus vs. estrus did not alter the results. Prenatal cocaine altered the PPI response function across interstimulus interval (ISI and induced significant sex-dependent changes in response latency. Idazoxan, an alpha2-adrenergic receptor antagonist, significantly enhanced the ASR, but less enhancement was noted with increasing doses of prenatal cocaine. Thus, in utero exposure to cocaine, when delivered via a protocol designed to capture prominent features of recreational usage, causes persistent, if not permanent, alterations in auditory information processing, and suggests dysfunction of the central noradrenergic circuitry modulating, if not mediating, these responses.

  10. Attachment of cells to basement membrane collagen type IV

    OpenAIRE

    1986-01-01

    Of ten different cell lines examined, three showed distinct attachment and spreading on collagen IV substrates, and neither attachment nor spreading was enhanced by adding soluble laminin or fibronectin. This reaction was not inhibited by cycloheximide or antibodies to laminin, indicating a direct attachment to collagen IV without the need of mediator proteins. Cell-binding sites were localized to the major triple-helical domain of collagen IV and required an intact triple helical conformatio...

  11. Collagen IV in normal skin and in pathological processes

    Directory of Open Access Journals (Sweden)

    Ana Maria Abreu-Velez

    2012-01-01

    Full Text Available Context: Type IV collagen is a type of collagen found primarily in the skin within the basement membrane zone. The type IV collagen C4 domain at the C-terminus is not removed in post-translational processing, and the fibers are thus link head-to-head, rather than in a parallel fashion. Also, type IV collagen lacks a glycine in every third amino-acid residue necessary for the tight collagen helix. Thus, the overall collagen-IV conformation is structurally more pliable and kinked, relative to other collagen subtypes. These structural features allow collagen IV to form sheets, which is the primary structural form found in the cutaneous basal lamina. There are six human genes associated with collagen IV, specifically COL4A1, COL4A2, COL4A3, COL4A4, COL4A5 and COL4A6. The aim of this review is to highlight the significance of this protein in normal skin, and in selected diseases. Results: The alpha 3 protein constituent of type IV collagen is thought to be the antigen implicated in Goodpasture′s syndrome, wherein the immune system attacks the basement membranes of the renal glomeruli and pulmonary alveoli. In addition, mutations to the genes coding for type IV collagen lead to the Alport syndrome. Furthermore, autoantibodies directed against denatured human type IV collagen have been described in rheumatoid arthritis, scleroderma, and SLE. Structural studies of collagen IV have been utilized to differentiate between subepidermal blistering diseases, including bullous pemphigoid, acquired epidermolysis bullosa, anti-epiligrin cicatricial pemphigoid, and bullous lupus erythematosus. Collagen IV is also of importance in wound healing and in embryogenesis. Conclusions: Pathological studies have demonstrated that minor structural differences in collagen IV can lead to distinct, clinically different diseases.

  12. Central bank Financial Independence

    OpenAIRE

    J.Ramon Martinez-Resano

    2004-01-01

    Central bank independence is a multifaceted institutional design. The financial component has been seldom analysed. This paper intends to set a comprehensive conceptual background for central bank financial independence. Quite often central banks are modelled as robot like maximizers of some goal. This perspective neglects the fact that central bank functions are inevitably deployed on its balance sheet and have effects on its income statement. A financially independent central bank exhibits ...

  13. BALTICA IV. Plant maintenance for managing life and performance

    Energy Technology Data Exchange (ETDEWEB)

    Hietanen, S.; Auerkari, P. [eds.] [VTT Manufacturing Technology, Espoo (Finland). Operational Reliability

    1998-12-31

    BALTICA IV International Conference on Plant Maintenance Managing Life and performance held on September 7-9, 1998 on board M/S Silja Symphony on its cruise between Helsinki-Stockholm and at Aavaranta in Kirkkonummi. The BALTICA IV conference provides a forum for the transfer of technology from applied research to practice. This is one of the two volumes of the proceedings of the BALTICA IV International Conference on Plant Maintenance Managing Life and Performance. The BALTICA IV conference focuses on new technology, recent experience and applications of condition and life management, and on improvements in maintenance strategies for safe and economical operation of power plants. (orig.)

  14. IV therapy and infection control in patients in the community.

    Science.gov (United States)

    Higginson, Ray

    Universal precautions and general infection control measures need to be considered when undertaking any clinical procedure, but when administering intravenous (IV) therapy (medicines and/or maintenance fluids), specific measures need to be considered. This is especially important for vulnerable patients or if administering IV therapy in the home environment. There are many reasons why patients may need to receive IV therapy in the community, and these will all present nurses with specific problems. This article discusses some of the infection control procedures one must undertake when administering IV therapy to patients in the community.

  15. DNA Ligase IV regulates XRCC4 nuclear localization.

    Science.gov (United States)

    Francis, Dailia B; Kozlov, Mikhail; Chavez, Jose; Chu, Jennifer; Malu, Shruti; Hanna, Mary; Cortes, Patricia

    2014-09-01

    DNA Ligase IV, along with its interacting partner XRCC4, are essential for repairing DNA double strand breaks by non-homologous end joining (NHEJ). Together, they complete the final ligation step resolving the DNA break. Ligase IV is regulated by XRCC4 and XLF. However, the mechanism(s) by which Ligase IV control the NHEJ reaction and other NHEJ factor(s) remains poorly characterized. Here, we show that a C-terminal region of Ligase IV (aa 620-800), which encompasses a NLS, the BRCT I, and the XRCC4 interacting region (XIR), is essential for nuclear localization of its co-factor XRCC4. In Ligase IV deficient cells, XRCC4 showed deregulated localization remaining in the cytosol even after induction of DNA double strand breaks. DNA Ligase IV was also required for efficient localization of XLF into the nucleus. Additionally, human fibroblasts that harbor hypomorphic mutations within the Ligase IV gene displayed decreased levels of XRCC4 protein, implicating that DNA Ligase IV is also regulating XRCC4 stability. Our results provide evidence for a role of DNA Ligase IV in controlling the cellular localization and protein levels of XRCC4.

  16. Type IV collagen-degrading enzyme activity in human serum.

    Directory of Open Access Journals (Sweden)

    Hashimoto,Noriaki

    1988-02-01

    Full Text Available Type IV collagen-degrading enzyme activity was detected in human serum. Serum was preincubated with 4-aminophenylmercuric acetate and trypsin to activate the enzyme prior to assay. Type IV collagen, purified from human placentas and radiolabeled with [1-14C] acetic anhydride, was used as the substrate. The enzyme activity was measured at pH 7.5 and inhibited by treatment with ethylenediaminetetraacetic acid or heat. The assay of type IV collagen-degrading enzyme in human serum might be useful for estimating the degradation of type IV collagen.

  17. Evaluation conjointe de la WAIS-IV et de la MEM-IV

    OpenAIRE

    Paumier, Delphine

    2016-01-01

    L’intelligence et la mémoire, composantes essentielles du fonctionnement cognitif, sont régulièrement évaluées lors d’un bilan psychologique. Chez l’adulte, l’intelligence s’évalue avec la WAIS-IV et la mémoire avec la MEM-IV. Dans notre étude, nous avons évalué conjointement ces batteries en administrant leurs sous-tests principaux à 66 personnes âgées de 18 à 50 ans. Comme ces échelles s’interprètent selon des indices distincts, nous proposons d’utiliser le modèle CHC comme grille de lectur...

  18. Inhibidores de dipeptidil dipeptidasa-IV: de la teoría a la práctica

    Directory of Open Access Journals (Sweden)

    Yessica Agudelo-Zapata

    2015-04-01

    Full Text Available Esta revisión de los inhibidores de dipeptidil peptidasa-IV busca motivar el uso racional de tal grupo farmacológico en la práctica diaria. Este grupo es una nueva opción terapéutica en monoterapia o terapia combinada para el tratamiento de los pacientes con diabetes mellitus tipo 2. En Colombia, se encuentran disponibles: sitagliptina, vildagliptina, saxagliptina y linagliptina. Si bien todas las gliptinas tienen el mismo mecanismo de acción-aumentan la vida media del péptido similar al glucagón-, esta revisión presenta las diferencias entre sus propiedades farmacológicas, eventos adversos y perfil de seguridad. Estos medicamentos son de segunda o tercera línea para el tratamiento oral de los pacientes con diabetes mellitus tipo 2, o primera línea en los pacientes intolerantes a la metformina. Además, algunas de las ventajas que tienen son que: generan menor riesgo de hipoglucemia, tienen efecto neutro sobre el peso, son seguros en adultos mayores, disminuyen la variabilidad de la glucemia y, adicionalmente, se pueden utilizar en la enfermedad renal crónica avanzada, con o sin terapia de reemplazo renal, y en la insuficiencia hepática.

  19. Involvement of insulin-regulated aminopeptidase in the effects of the renin-angiotensin fragment angiotensin IV: a review.

    Science.gov (United States)

    Stragier, Bart; De Bundel, Dimitri; Sarre, Sophie; Smolders, Ilse; Vauquelin, Georges; Dupont, Alain; Michotte, Yvette; Vanderheyden, Patrick

    2008-09-01

    For decades, angiotensin (Ang) II was considered as the end product and the only bioactive peptide of the renin-angiotensin system (RAS). However, later studies revealed biological activity for other Ang fragments. Amongst those, Ang IV has drawn a lot of attention since it exerts a wide range of central and peripheral effects including the ability to enhance learning and memory recall, anticonvulsant and anti-epileptogenic properties, protection against cerebral ischemia, activity at the vascular level and an involvement in atherogenesis. Some of these effects are AT(1) receptor dependent but others most likely result from the binding of Ang IV to insulin-regulated aminopeptidase (IRAP) although the exact mechanism(s) of action that mediate the Ang IV-induced effects following this binding are until now not fully known. Nevertheless, three hypotheses have been put forward: since Ang IV is an inhibitor of the catalytic activity of IRAP, its in vivo effects might result from a build-up of IRAP's neuropeptide substrates. Second, IRAP is co-localized with the glucose transporter GLUT4 in several tissue types and therefore, Ang IV might interact with the uptake of glucose. A final and more intriguing hypothesis ascribes a receptor function to IRAP and hence an agonist role to Ang IV. Taken together, it is clear that further work is required to clarify the mechanism of action of Ang IV. On the other hand, a wide range of studies have made it clear that IRAP might become an important target for drug development against different pathologies such as Alzheimer's disease, epilepsy and ischemia.

  20. Astragaloside IV suppresses transforming growth factor-β1 induced fibrosis of cultured mouse renal fibroblasts via inhibition of the MAPK and NF-κB signaling pathways

    Energy Technology Data Exchange (ETDEWEB)

    Che, Xiajing; Wang, Qin; Xie, Yuanyuan; Xu, Weijia; Shao, Xinghua; Mou, Shan, E-mail: shan_mou@126.com; Ni, Zhaohui, E-mail: doctor_nzh@126.com

    2015-09-04

    Renal fibrosis, a progressive process characterized by the accumulation of extracellular matrix (ECM) leading to organ dysfunction, is a characteristic of chronic kidney diseases. Among fibrogenic factors known to regulate the renal fibrotic process, transforming growth factor-β (TGF-β) plays a central role. In the present study, we examined the effect of Astragaloside IV (AS-IV), a component of the traditional Chinese medicinal plant Astragalus membranaceus, on the processes associated with renal fibrosis in cultured mouse renal fibroblasts treated with TGF-β1. RT-PCR, western blotting, immunofluorescence staining and collagen assays showed that AS-IV suppressed TGF-β1 induced fibroblast proliferation, transdifferentiation, and ECM production in a dose-dependent manner. Examination of the underlying mechanisms showed that the effect of AS-IV on the inhibition of fibroblast differentiation and ECM formation were mediated by its modulation of the activity of the MAPK and NF-κB signaling pathways. Taken together, our results indicate that AS-IV alleviates renal interstitial fibrosis via a mechanism involving the MAPK and NF-κB signaling pathways and demonstrate the therapeutic potential of AS-IV for the treatment of chronic kidney diseases. - Highlights: • AS-IV suppressed TGF-β1 induced renal fibroblast proliferation. • AS-IV suppressed TGF-β1 induced renal fibroblast transdifferentiation. • AS-IV suppressed TGF-β1 induced ECM production. • AS-IV alleviates renal fibrosis via the MAPK and NF-κB signaling pathways.

  1. Influencia del contacto precoz, nacionalidad, tipo de parto y prematuridad en la lactancia materna

    Directory of Open Access Journals (Sweden)

    Ana Belén Laviña Castan

    2015-01-01

    Full Text Available Conocer si en el HUMS existe asociación entre lactancia materna y nacionalidad, prematuridad, tipo de parto, contacto precoz piel con piel. Estudio de cohortes, en una muestra de 541 puérperas del HUMS en octubre-noviembre 2011. Las variables: nacionalidad, tipo de parto, contacto precoz, parto prematuro e inicio lactancia materna se recogieron antes del alta hospitalaria mediante cuestionario. A los dos meses postparto se contactó telefónicamente con las madres para conocer el tipo de lactancia en ese momento. El 70,32 % iniciaron la lactancia materna en las dos primeras horas postparto y el 55,58% daban Lactancia materna exclusiva (LME a los dos meses. Influyen en la lactancia materna el tipo de parto, contacto precoz y parto prematuro. La probabilidad de lactancia materna es 3,65 veces más alta si se ha realizado contacto precoz (RR 3,65; IC 95% 2,72-4,88; p=0,001. El inicio de lactancia materna en las 2 primeras horas y la nacionalidad española influye positivamente en la LME a los 2 meses. Las prácticas hospitalarias en el postparto deben promover el contacto precoz madre-recién nacido y el inicio de lactancia materna en las dos primeras horas, principalmente en las cesáreas.

  2. Control predictivo basado en modelo de un campo de colectores solares tipo acurex

    OpenAIRE

    Flor Unda, Omar Cristóbal

    2013-01-01

    El presente trabajo, presenta los resultados del control de un sistema de colectores solares tipo ACUREX, aplicando control predictivo basado en modelo como una técnica que aporta criterios para su estudio y mejoramiento. Se ha empleado el simulador creado para entorno Simulink, trabajo de (Camacho, et al., 1997).

  3. Quebrando estereótipos e rompendo preconceitos na sala de aula

    Directory of Open Access Journals (Sweden)

    Daniela Jakubaszko

    2015-04-01

    Full Text Available Este texto se preocupa em contribuir para a reflexão que torna possível a identificação e ruptura dos estereótipos sociais que dão origem a preconceitos e ações discriminatórias. Com base nos estudos de Walter Lippann, Agnes Heller, Adam Shaff e Eclea Bosi, pretende-se discutir os conceitos de estereótipo e preconceito, buscando entender o que são e porque se formam. Para entender melhor o estereótipo temos que refletir sobre três elementos que a ele se ligam: a linguagem, o cotidiano e o senso comum. É no plano da linguagem - do diálogo e das práticas de linguagem - que se deve estudar e se pode romper e desconstruir os estereótipos, tomando consciência da própria formação discursiva. O texto oferece, ainda, algumas sugestões para trabalhar o conceito na sala de aula e para ampliar o repertório de textos e referências a serem debatidas com os alunos.

  4. CORRELACION ENTRE DISTINTOS TIPOS HISTOLOGICOS DE CANCER DE MAMA Y RECEPTORES ESTROGENICOS

    OpenAIRE

    Schiaffino O.,Rodrigo; Ibarra P.,Andrés; González A.,Raúl; Urrutia M.,Julio

    2002-01-01

    Se presentan los resultados de 140 muestras histológicas tomadas en pacientes con cáncer de mama para determinar su concentración de receptores de estrógenos. Destaca la importancia, frecuencia de positividad para receptores de estrógenos en todos los tipos histológicos

  5. A classification system for O-B2 stars based on the Si IV and C IV resonance lines

    Science.gov (United States)

    Henize, K. G.; Wray, J. D.; Parsons, S. B.

    1981-01-01

    Low-dispersion ultraviolet spectra from Skylab Experiment S-019 are used to explore the variations of Si IV and C IV line strengths with temperature and luminosity. These considerations lead to a classification system in which the Si/C ratio is used to discriminate luminosity among the O stars and temperature among the O9-B2 stars of lower luminosity. Stars falling in these two regimes may be distinguished either by the presence of C IV emission or on the basis of C IV absorption strength. The log(Si IV/C IV) vs C IV diagram is proposed as a primary tool in such a classification system. The rapid variation in the Si IV/C IV ratio from less than 1/10 at O9 to greater than 10 at B1.5 for luminosity class III-V stars appears to be an especially useful criterion for the temperature classification of stars in this spectral range.

  6. New mono-organotin (IV) dithiocarbamate complexes

    Energy Technology Data Exchange (ETDEWEB)

    Muthalib, Amirah Faizah Abdul; Baba, Ibrahim [School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi (Malaysia)

    2014-09-03

    Eighteen new mono-organotin dithiocarbamate compounds derived each nine from methyltin(IV) and phenyltin(IV) reacted using in-situ method with various type of N-dialkylamine together with carbon disulphide with the ratio of 1:3:3. Elemental and gravimetric analysis showed that the general formula of these compounds were RSnCl[S{sub 2}CNR′R″]{sub 2} (R= Ph, CH{sub 3}, R′ = CH{sub 3}, C{sub 2}H{sub 5}, C{sub 7}H{sub 7} and R″ = C{sub 2}H{sub 5}, C{sub 6}H{sub 11}, iC{sub 3}H{sub 7}, C{sub 7}H{sub 7}). These compounds had been characterized by infrared spectroscopy, ultraviolet spectroscopy, {sup 1}H, {sup 13}C NMR spectroscopy and single crystal X-ray crystallography. The infrared spectra of these compounds showed three important peaks indicating the formation of dithiocarbamate compounds, ν(CN), ν(CS) and ν(Sn-S) band which present in the region of 1444–1519, 954–1098 and 318–349 cm{sup −1} respectively. The ultraviolet-visible spectra showed an absorption band for the π - π* transition of NCS group in the range of 253 – 259 nm due to the intramolecular charge transfer of the ligand. The {sup 13}C NMR spectra showed an important shift for δ(N{sup 13}CS{sub 2}) in the range of 196.8 – 201.9 ppm.. Single crystal X-ray diffraction studies showed three new structures with the general formula of PhSnCl[S{sub 2}CN(Et)(i−Pr)]{sub 2}, MeSnCl[S{sub 2}CN(Me)(Cy)]{sub 2} and MeSnCl[S{sub 2}CN(i−Pr)(CH{sub 2}Ph)]{sub 2}. All structures having a distorted octahedral geometry set by CClS{sub 4} donor atom from the two

  7. Toward Phase IV, Populating the WOVOdat Database

    Science.gov (United States)

    Ratdomopurbo, A.; Newhall, C. G.; Schwandner, F. M.; Selva, J.; Ueda, H.

    2009-12-01

    One of challenges for volcanologists is the fact that more and more people are likely to live on volcanic slopes. Information about volcanic activity during unrest should be accurate and rapidly distributed. As unrest may lead to eruption, evacuation may be necessary to minimize damage and casualties. The decision to evacuate people is usually based on the interpretation of monitoring data. Over the past several decades, monitoring volcanoes has used more and more sophisticated instruments. A huge volume of data is collected in order to understand the state of activity and behaviour of a volcano. WOVOdat, The World Organization of Volcano Observatories (WOVO) Database of Volcanic Unrest, will provide context within which scientists can interpret the state of their own volcano, during and between crises. After a decision during the 2000 IAVCEI General Assembly to create WOVOdat, development has passed through several phases, from Concept Development (Phase-I in 2000-2002), Database Design (Phase-II, 2003-2006) and Pilot Testing (Phase-III in 2007-2008). For WOVOdat to be operational, there are still two (2) steps to complete, which are: Database Population (Phase-IV) and Enhancement and Maintenance (Phase-V). Since January 2009, the WOVOdat project is hosted by Earth Observatory of Singapore for at least a 5-year period. According to the original planning in 2002, this 5-year period will be used for completing the Phase-IV. As the WOVOdat design is not yet tested for all types of data, 2009 is still reserved for building the back-end relational database management system (RDBMS) of WOVOdat and testing it with more complex data. Fine-tuning of the WOVOdat’s RDBMS design is being done with each new upload of observatory data. The next and main phase of WOVOdat development will be data population, managing data transfer from multiple observatory formats to WOVOdat format. Data population will depend on two important things, the availability of SQL database in volcano

  8. No-choice ovipositional nonpreference of Bemisia tabaci (Gennadius B biotype on tomato genotypes Não-preferência para oviposição de Bemisia tabaci (Gennadius biótipo B em genótipos de tomateiro em teste sem chance de escolha

    Directory of Open Access Journals (Sweden)

    Maria Auxiliadora de Godoy Oriani

    2011-04-01

    to a high density of type V nonglandular trichomes.O Brasil é um dos maiores produtores mundiais de tomate, porém grande parte da produção é perdida devido ao ataque de Bemisia tabaci (Gennadius biótipo B. Entre as táticas de controle dessa praga num manejo integrado de pragas, pode-se relacionar a resistência de plantas. Avaliou-se a preferência para oviposição de B. tabaci biótipo B por 18 genótipos de tomateiro com diferentes densidades e tipos de tricomas utilizando-se dois métodos e estudou-se a influência dos tricomas nesta preferência, utilizando-se dois métodos para os experimentos de confinamento. Folíolos seccionados do terço superior dos tomateiros (primeiro método e plantas com 30 dias de idade (segundo método foram infestados com moscas-brancas durante 24 h. Para o primeiro experimento, foram realizados testes de correlação linear simples entre o número de insetos e de ovos e o número de tricomas nos tomateiros. O primeiro método foi melhor que o segundo, pois foi mais fácil de ser conduzido e demandou menos tempo para as avaliações, além disso, foi efetivo em discriminar o nível de resistência dos genótipos avaliados. Tricomas glandulares correlacionaram-se negativamente com adultos atraídos e com ovos, e positivamente com adultos capturados. Correlações negativas ocorreram entre o número de tricomas não-glandulares e o número de insetos capturados, e entre o número de tricomas totais e o número de insetos atraídos e capturados. Correlações positivas ocorreram entre o número de tricomas totais e o número de ovos cm-2 e de tricomas não-glandulares e o número de ovos. Ambos os métodos foram eficientes para discriminar os genótipos, principalmente os resistentes, com destaque para LA716, PI134417 e PI134418, que apresentaram altíssima antixenose para oviposição relacionada à presença de tricomas glandulares tipo IV. A preferência para oviposição de B. tabaci pelos genótipos LA1963 e NAV1062 est

  9. Implicaciones didácticas de Geogebra sobre el aprendizaje significativo de los tipos de funciones en estudiantes del último grado de secundaria

    Directory of Open Access Journals (Sweden)

    Edwin David Tamayo Martínez

    2013-10-01

    Full Text Available Este trabajo presenta los resultados de una investigación de carácter cualitativo cuyo propósito fue la evaluación del Geogebra para determinar implicaciones didácticas relacionadas con el uso de este tipo de recurso educativo en la enseñanza y el aprendizaje de las matemáticas. El estudio indagó, partiendo de las percepciones de estudiantes y docente, las debilidades y fortalezas de este recurso y dedujo implicaciones en el aprendizaje significativo. Se realizaron tres talleres para el análisis de los diferentes tipos de funciones con estudiantes del grado 11 del Colegio Colombo Francés del municipio de La Estrella (Antioquia, Colombia; estos talleres fueron objeto de reflexión sobre cuatro aspectos centrales: dificultades más comunes al implementar el recurso; fortalezas que puedan orientar reflexiones didácticas; descripción de las interacciones entre estudiantes y docente que fortalecen la aplicación del Geogebra; y principales necesidades para mejorar las intervenciones en el aula.

  10. Quantitative neuroimaging in mucolipidosis type IV.

    Science.gov (United States)

    Schiffmann, Raphael; Mayfield, Joan; Swift, Caren; Nestrasil, Igor

    2014-02-01

    Mucolipidosis type IV (MLIV) is an autosomal recessive disorder resulting from mutations in the MCOLN1 gene. This gene encodes the endosomal/lysosomal transient receptor potential channel protein mucolipin-1 (TRPML1). Affected patients suffer from neurodevelopmental abnormalities and progressive retinal dystrophy. In a prospective natural history study we hypothesized the presence of an additional slow cerebral neurodegenerative process. We have recruited 5 patients, tested their neurodevelopmental status, and measured cerebral regional volumes and white matter integrity using MRI yearly. Over a period of up to 3 years, MLIV patients remained neurologically stable. There was a trend for increased cortical and subcortical gray matter volumes and increased ventricular size, while white matter and cerebellar volumes decreased. Mean diffusivity (MD) was increased and fractional anisotropy (FA) values were below normal in all analyzed brain regions. There was a positive correlation between motor scores of the Vineland Scale and the FA values in the corticospinal tract (corr coef 0.39), and a negative correlation with the MD values (corr coef -0.50) in the same brain region. We conclude from these initial findings that deficiency in mucolipin-1 affects the entire brain but that there might be a selective regional cerebral neurodegenerative process in MLIV. In addition, these data suggest that diffusion-weighted imaging might be a good biomarker for following patients with MLIV. Therefore, our findings may be helpful for designing future clinical trials.

  11. Tipo de tratamiento farmacológico y deterioro de la función pulmonar en pacientes con diabetes tipo 2

    OpenAIRE

    Vargas Diaz, Henry Alexander; Dennis Verano, Rodolfo José

    2013-01-01

    Antecedentes: En la actualidad no es clara la relación de la DM 2 con respecto al deterioro de la función pulmonar y menos aún si el tipo de tratamiento modifica parámetros espirométricos e inflamatorios. Objetivo: Comparar la función pulmonar de pacientes con DM 2 tratados con metformina vs secretagogos y la combinación con insulinas. Establecer el nivel de biomarcadores inflamatorios entre los grupos de tratamiento. Metodología: Estudio observacional analítico de corte transversal 495 pacie...

  12. Control predictivo de canales de riego utilizando modelos de predicción de tipo Muskingum (primer orden) y de tipo Hayami (segundo orden)

    OpenAIRE

    Alvarez Brotons, Xavier

    2004-01-01

    En el desarrollo de los algoritmos de control predictivo a aplicar en la gestión de canales de riego, es necesario considerar un modelo simplificado que represente la dinámica hidráulica del canal. En esta tesina se pretende comparar el rendimiento de diferentes algoritmos de control basados en modelos hidráulicos de la dinámica del canal, en particular un modelo de primer orden, como el modelo de Muskingum de tipo hidrológico y basado en la ecuación de continuidad y una relación de almacenam...

  13. FORTRAN IV Digital Filter Design Programs. Digital Systems Education Project.

    Science.gov (United States)

    Reuss, E.; And Others

    The goals of the Digital Systems Education Project (DISE) include the development and distribution of educational/instructional materials in the digital systems area. Toward that end, this document contains three reports: (1) A FORTRAN IV Design Program for Low-Pass Butterworth and Chebychev Digital Filters; (2) A FORTRAN IV Design Program for…

  14. On the ion chromatographic determination of S(IV)

    Science.gov (United States)

    Dasgupta, Purnendu K.

    Ion Chromatographie determination of S(IV) is described with special reference to the determination of SO 2(g) and/or aerosol S(IV) along with chloride, nitrate and sulfate in particulate matter. A method is presented for the baseline separation of the above species. The Chromatographic behavior of hydroxymethanesulfonate under various eluent conditions is discussed.

  15. Beyond the DSM-IV: Assumptions, Alternatives, and Alterations

    Science.gov (United States)

    Lopez, Shane J.; Edwards, Lisa M.; Pedrotti, Jennifer Teramoto; Prosser, Ellie C.; LaRue, Stephanie; Spalitto, Susan Vehige; Ulven, Jon C.

    2006-01-01

    Current diagnostic processes reflect the limitations and utility of the framework of the "Diagnostic and Statistical Manual of Mental Disorders" (4th ed.; DSM-IV; American Psychiatric Association, 1994). Clinical information in the DSM-IV's 5-axis system almost exclusively focuses on weaknesses and pathology and is summarized in a flawed…

  16. CDDIS Data Center Summary for the IVS 2012 Annual Report

    Science.gov (United States)

    Noll, Carey

    2013-01-01

    This report summarizes activities during 2012 and future plans of the Crustal Dynamics Data Information System (CDDIS) with respect to the International VLBI Service for Geodesy and Astrometry (IVS). Included in this report are background information about the CDDIS, the computer architecture, staff supporting the system, archive contents, and future plans for the CDDIS within the IVS.

  17. Metoclopramida, factor de riesgo para hiperglucemia postprandial en diabetes tipo 2 Metoclopramide as a risk factor for postprandial hyperglycemia in type 2 diabetes

    Directory of Open Access Journals (Sweden)

    H. Gutiérrez-Hermosillo

    2012-08-01

    Full Text Available La diabetes mellitus (DM es una patología que ha crecido ampliamente a nivel mundial en las ultimas décadas. La hiperglucemia postprandial (HP ha tomado importancia en los últimos años, ya que se ha visto se relaciona de manera directa con un aumento en el riesgo de eventos cardiovasculares. A la fecha, no se ha determinado la asociación entre el empleo de metoclopramida y los niveles de glucemia postprandial. Material y métodos: Se realizó un estudio de tipo cohorte, con objeto de determinar si la metoclopramida es factor de riesgo para hiperglucemia postprandial. Se incluyeron pacientes diabéticos tipo 2, se catalogó a los pacientes en expuestos, aquellos manejados con metoclopramida preprandial 10 mg intravenosa (IV y no expuestos, se determinó glucemia preprandial y 30, 60, 90 y 120 minutos postprandiales. Resultados: 80 pacientes por grupo se incluyeron siendo sus características basales similares. Las glucemia postprandial fue más elevada en aquellos tratados con metoclopramida que sin esta (p = Diabetes mellitus is a pathology that has widely spread througout the world in the past decades. Postprandial hyperglycemia plays an important role in the progress of the disease due to the fact that increases the risk for cardiovascular events. This study's aim was to determine if the use of intravenous metoclopramide in patients with Diabetes Mellitus increases the postprandial glycemia. Material and methods: A cohort of patients hospitalized with type 2 diabetes mellitus. Patients were classified as exposed (metoclopramide 10 mg IV and not exposed, and glycemia preprandial and postprandial at 30, 60 and 120 minutes was measured. Results: There were 80 patients in each group, and in both groups the general characteristics were homogeneous. The postprandial glycemia in the exposed group was higher at 30, 60, 90 and 120 minutes, being only statistically significant at 120 minutes postprandial (p = < 0,001. Conclusions: In conclusion

  18. Una función apotropaica de los amuletos de tipo egipcio en el mundo prerromano hispánico

    OpenAIRE

    2003-01-01

    En este articulo tratamos sobre la identificación en la costa mediterránea ibérica del uso apotropaico de los amuletos de tipo egipcio, revisando brevemente los principales hallazgos de este tipo en la esteras coloniales griegas y fenicio, así como en el ambiente indígena peninsular.

  19. Influencia del tipo de centro en la práctica deportiva y las actividades de tiempo libre de escolares

    Directory of Open Access Journals (Sweden)

    Victor Arufe-Giráldez

    2016-12-01

    Full Text Available Introducción: Recientes investigaciones han demostrado la importancia de las actividades extraescolares y de ocupación del tiempo libre en los niños y niñas en edad escolar, especialmente en el seno de la sociedad actual donde la creciente ocupación laboral de las familias apenas permite pasar tiempo con sus menores. En este sentido, presenta un papel central la práctica deportiva, pues ayudará a combatir el ocio digital sedentario tan extendido en los últimos años. Objetivos: Este estudio pretende determinar la práctica deportiva extraescolar y actividades de tiempo libre en una muestra de estudiantes de educación primaria, analizando su relación con el tipo de centro educativo en el que se encuentran matriculados o matriculadas. Diseño: Se realizó un estudio descriptivo de corte transversal de diseño multifactorial univariado. Participantes: Participaron un total de 786 estudiantes de educación primaria que se seleccionaron mediante muestreo aleatorio por conglomerados. Instrumentos: Se empleó un cuestionario Ad-hoc compuesto por 12 ítems relacionados con la práctica deportiva extraescolar. Análisis de datos: Se empleó SPSS 22.0 para los análisis estadísticos, con el empleo de tablas de contingencia, ANOVA o T de Student, dependiendo de la naturaleza de las variables. Resultados: Los resultados arrojaron medias aceptables de práctica deportiva, porcentajes considerablemente elevados de ocio de pantalla y significativamente bajos de lectura y tiempo invertido con pares y amistades. Según la tipología del colegio, se reveló que los grupos escolares de centros privados practican mayor número de deportes, adhiriéndose principalmente a los deportes colectivos. El alumnado de centros públicos se posiciona en deportes individuales e invierte más tiempo en ocio digital y con las amistades. De este modo, se demuestra la relación entre el tipo de centro y las actividades no curriculares, principalmente por motivos de

  20. NIDDK Central Repository

    Data.gov (United States)

    U.S. Department of Health & Human Services — The NIDDK Central Repository stores biosamples, genetic and other data collected in designated NIDDK-funded clinical studies. The purpose of the NIDDK Central...

  1. Central Neuropathic Pain Syndromes.

    Science.gov (United States)

    Watson, James C; Sandroni, Paola

    2016-03-01

    Chronic pain is common in patients with neurologic complications of a central nervous system insult such as stroke. The pain is most commonly musculoskeletal or related to obligatory overuse of neurologically unaffected limbs. However, neuropathic pain can result directly from the central nervous system injury. Impaired sensory discrimination can make it challenging to differentiate central neuropathic pain from other pain types or spasticity. Central neuropathic pain may also begin months to years after the injury, further obscuring recognition of its association with a past neurologic injury. This review focuses on unique clinical features that help distinguish central neuropathic pain. The most common clinical central pain syndromes-central poststroke pain, multiple sclerosis-related pain, and spinal cord injury-related pain-are reviewed in detail. Recent progress in understanding of the pathogenesis of central neuropathic pain is reviewed, and pharmacological, surgical, and neuromodulatory treatments of this notoriously difficult to treat pain syndrome are discussed.

  2. Central venous catheter - flushing

    Science.gov (United States)

    ... during cancer treatment Bone marrow transplant - discharge Central venous catheter - dressing change Peripherally inserted central catheter - flushing Sterile technique Surgical wound care - open Review Date 9/22/2016 Updated by: ...

  3. Instantánea de los cánceres de cerebro y del sistema nervioso central

    Science.gov (United States)

    Información sobre las tendencias de incidencia, mortalidad y financiamiento del NCI sobre los cánceres de cerebro y del sistema nervioso central; así como ejemplos de actividades del NCI y adelantos en la investigación de estos tipos de cáncer.

  4. El trabajo artesanal en Augusta Emerita durante los ss. I-IV d. C

    Directory of Open Access Journals (Sweden)

    Macarena BUSTAMANTE ÁLVAREZ

    2014-01-01

    Full Text Available Actualmente en la antigua capital lusitana es posible examinar, además de los restos arquitectónicos de sus edificios públicos y de una espléndida musivaria en ámbito doméstico, los indicios de otras producciones locales a las que hasta ahora no se les había concedido más que un interés de tipo secundario. En el presente trabajo damos a conocer una síntesis de las evidencias arqueológicas existentes del artesanado emeritense durante los ss. I-IV d. C. Este tema había sido revisado de manera aislada y esporádica en este solar. Aquí se valoran las estructuras, modos productivos y posibles evidencias de la mano de obra usada. Las constantes excavaciones que se han desarrollado en las últimas décadas han sacado a la luz 33 hornos cerámicos, 2 molinos alimentarios, 7 fullonicae, 1 officina infectae, 4 talleres de vidrio, 1 lanifricaria, 2 talleres de hueso, 2 pistrinae, 2 hornos metalúrgicos y 3 caleras que permiten el desarrollo de estudios de cierta envergadura. La industrial textil, la alfarera, alimentaria o metalúrgica, entre otras, son analizadas arqueológicamente. A partir de ello ha sido posible establecer un mapa de distribución de las distintas áreas manufactureras y de sus posibles zonas de influencia.

  5. De plantis vascularibus praesertim ibericis (IV

    Directory of Open Access Journals (Sweden)

    PEDROL, J., YERA, J., ASCASO, J.

    2002-01-01

    Full Text Available Se aportan algunas novedades florísticas y comentarios corológicos relativos a la zona central del Valle del Ebro (Huesca, Lérida y Zaragoza en España. Destacamos : Achillea filipendulina, Aegilops neglecta, Bbidens aurea, B. fondosa, Centaurea depressa, Chamaemelum nobile, Crypsis aculeata, Cyperus michelianus subsp. michelianus, C. serotinus, Heteranthera reniformis, Mantisalca duriaei, Pulicaria paludosa, Ranunculus sardous, Reichardia intermedia, Scirpus lacustris subsp. lacustris, S. mucronatus, S. supinus, seneciio lagascanus, Sonchus x novocastellanus y Valerianella eriocarpa.

  6. Expanding the Ecological Validity of WAIS-IV and WMS-IV with the Texas Functional Living Scale

    Science.gov (United States)

    Drozdick, Lisa Whipple; Cullum, C. Munro

    2011-01-01

    Assessment of functional status is an important aspect of clinical evaluation. As part of the standardization of the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) and Wechsler Memory Scale-Fourth Edition (WMS-IV), participants completed the Texas Functional Living Scale (TFLS), a measure of Instrumental Activities of Daily Living. The…

  7. Actinide Corroles: Synthesis and Characterization of Thorium(IV) and Uranium(IV) bis(-chloride) Dimers

    Energy Technology Data Exchange (ETDEWEB)

    Ward, Ashleigh L.; Buckley, Heather L.; Gryko, Daniel T.; Lukens, Wayne W.; Arnold, John

    2013-12-01

    The first synthesis and structural characterization of actinide corroles is presented. Thorium(IV) and uranium(IV) macrocycles of Mes2(p-OMePh)corrole were synthesised and characterized by single-crystal X-ray diffraction, UV-Visible spectroscopy, variable-temperature 1H NMR, ESI mass spectrometry and cyclic voltammetry.

  8. Comparative distribution of the alpha 1(IV), alpha 5(IV), and alpha 6(IV) collagen chains in normal human adult and fetal tissues and in kidneys from X-linked Alport syndrome patients.

    OpenAIRE

    Peissel, B; Geng, L.; Kalluri, R.; Kashtan, C; Rennke, H G; Gallo, G R; Yoshioka, K.; Sun, M J; Hudson, B.G.; Neilson, E. G.

    1995-01-01

    We have shown previously that the 5' ends of the genes for the alpha 5(IV) and alpha 6(IV) collagen chains lie head-to-head on Xq22 and are deleted in patients with Alport syndrome (AS)-associated diffuse leiomyomatosis. In this study, we raised a rabbit anti-human alpha 6(IV)chain antibody, demonstrated its specificity by the analysis of recombinant NC1 domains af all six type IV chains, and studied the distribution of the alpha 6(IV) chain in relation to the alpha 1(IV) and alpha 5(IV) chai...

  9. Salga de queijo tipo Minas por impregnação a vácuo Salting of Minas cheese by vacuum impregnation

    Directory of Open Access Journals (Sweden)

    Luciana C. Hofmeister

    2005-09-01

    Full Text Available Estudou-se o uso da impregnação a vácuo (IV para a salga de queijo tipo Minas, utilizando-se uma câmara hermética, na qual amostras de queijos (cilíndricos, com massa de 500g e dimensões de 120mm de raio por 60mm de altura foram imersas em solução de salmoura com 22% em massa de NaCl. Os ensaios foram realizados após a etapa de enformagem e prensagem, para facilitar a reprodutibilidade estrutural dos queijos. Utilizou-se vácuo de 85,3kPa (Pabsoluta =16kPa, aplicado intermitentemente, intercalado com a recuperação da pressão atmosférica na câmara. Após períodos pré-estabelecidos, a câmara foi aberta e os queijos foram pesados e secionados, de modo a permitir a determinação da distribuição de sal no interior dos mesmos pelo método de Mohr. A salga por IV permitiu a obtenção de queijos com 1,6% em massa de sal em 15 minutos, contra 2,5 horas da salga convencional. Além disso, a distribuição de sal nos queijos salgados por IV foi mais homogênea do que nos queijos salgados por imersão em salmoura a pressão atmosférica. Esses resultados indicaram que a salga de queijos tipo Minas por IV pode ser uma boa alternativa de processamento, tanto do ponto de vista econômico como tecnológico.Minas cheese salting by vacuum impregnation was studied using cylindrical cheese samples of about 500 g and 120 ' 60mm (radius ' height, that were immersed in a hermetic chamber with 22g NaCl/100g, where sub-atmospheric pressures were applied. The essays were performed after the press stage, used in this to obtain more compact cheeses and facilitate the reproducibility of an average cheese pore structure. Vacuum intensity of 85.3kPa (absolute pressure of 16kPa was applied intermittently, interleaving with the atmospheric pressure recuperation in the chamber. After pre-determined periods, the chamber was opened and the cheeses were weighed and cut, in order to determine the salt concentration distributions, by means of a modified Mohr

  10. Irradiation Alters MMP-2/TIMP-2 System and Collagen Type IV Degradation in Brain

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Won Hee [School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia (United States); Warrington, Junie P.; Sonntag, William E. [Reynolds Oklahoma Center on Aging, Department of Geriatric Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma (United States); Lee, Yong Woo, E-mail: ywlee@vt.edu [School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia (United States); Department of Biomedical Sciences and Pathobiology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia (United States)

    2012-04-01

    Purpose: Blood-brain barrier (BBB) disruption is one of the major consequences of radiation-induced normal tissue injury in the central nervous system. We examined the effects of whole-brain irradiation on matrix metalloproteinases (MMPs)/tissue inhibitors of metalloproteinases (TIMPs) and extracellular matrix (ECM) degradation in the brain. Methods and Materials: Animals received either whole-brain irradiation (a single dose of 10 Gy {gamma}-rays or a fractionated dose of 40 Gy {gamma}-rays, total) or sham-irradiation and were maintained for 4, 8, and 24 h following irradiation. mRNA expression levels of MMPs and TIMPs in the brain were analyzed by real-time reverse transcriptase-polymerase chain reaction (PCR). The functional activity of MMPs was measured by in situ zymography, and degradation of ECM was visualized by collagen type IV immunofluorescent staining. Results: A significant increase in mRNA expression levels of MMP-2, MMP-9, and TIMP-1 was observed in irradiated brains compared to that in sham-irradiated controls. In situ zymography revealed a strong gelatinolytic activity in the brain 24 h postirradiation, and the enhanced gelatinolytic activity mediated by irradiation was significantly attenuated in the presence of anti-MMP-2 antibody. A significant reduction in collagen type IV immunoreactivity was also detected in the brain at 24 h after irradiation. In contrast, the levels of collagen type IV were not significantly changed at 4 and 8 h after irradiation compared with the sham-irradiated controls. Conclusions: The present study demonstrates for the first time that radiation induces an imbalance between MMP-2 and TIMP-2 levels and suggests that degradation of collagen type IV, a major ECM component of BBB basement membrane, may have a role in the pathogenesis of brain injury.

  11. ANÁLISE MORFOLÓGICA DE ISOFORMAS DE MIOSINA NÃO MUSCULAR TIPO II EM CARCINOMA EPIDERMÓIDE

    OpenAIRE

    Otávio Francisco Gomes Dias

    2012-01-01

    A migração celular é uma característica proeminente na metástase do câncer e a caracterização de proteínas relacionadas com a migração é importante para que se compreenda o comportamento de células tumorais e sua capacidade de invasão durante a progressão tumoral. Entre as proteínas envolvidas na migração celular, as isoformas de miosina não-muscular do tipo II desempenham um papel central em vários eventos relacionados com a migração de células, como a contratilidade, a adesão e a sinalizaçã...

  12. Group IV photonics for the mid infrared

    Science.gov (United States)

    Soref, Richard

    2013-02-01

    This paper outlines the challenges and benefits of applying silicon-based photonic techniques in the 2 to 5 μm midinfrared (MIR) wavelength range for chem.-bio-physical sensing, medical diagnostics, industrial process control, environmental monitoring, secure communications, Ladar, active imaging, and high-speed communications at 2 μm. Onchip passive and active components, mostly waveguided, will enable opto-electronic CMOS or BiCMOS integrated "circuits" for system-on-a-chip applications such as spectroscopy and lab-on-a-chip. Volume manufacture in a silicon foundry is expected to yield low-cost (or even disposable) chips with benefits in size-weight-power and ruggedness. This is "long-wavelength optoelectronic integration on silicon" which we call LIOS. Room temperature operation appears feasible, albeit with performance compromises at 4 to 5 μm. In addition to the electronics layer (which may include RF wireless), a 3-D LIOS chip can include several inter-communicating layers utilizing the photonic, plasmonic, photoniccrystal and opto-electro-mechanical technologies. The LIOS challenge can be met by (1) discovering new physics, (2) employing "new" IV and III-V alloys, (3) scaling-up and modifying telecom components, and (4) applying nonlinearoptical wavelength conversion in some cases. This paper presents proposals for MIR chip spectrometers employing frequency-comb and Ge blackbody sources. Active heterostructures employing Si, Ge, SiGe, GeSn and SiGeSn are key for laser diodes, photodetectors, LEDs, switches, amplifiers, and modulators that provide totally monolithic foundry integration, while numerous III-V semiconductor MIR devices within the InGaAsSb and InGaAsP families offer practical hybrid integration on Si PICs. Interband cascade and quantum cascade lasers on Ge waveguides are important in this context.

  13. Intermetallic communication in titanium(IV) ferrocenyldiketonates.

    Science.gov (United States)

    Dulatas, Lea T; Brown, Seth N; Ojomo, Edema; Noll, Bruce C; Cavo, Matthew J; Holt, Paul B; Wopperer, Matthew M

    2009-11-16

    A tetradentate bis(ferrocenyldiketonate) ligand, Fc(2)BobH(2), is prepared via Claisen condensation of acetylferrocene and 2,2'-biphenyldiacetyl chloride, and is metalated with titanium(IV) isopropoxide to give (Fc(2)Bob)Ti(O(i)Pr)(2) in good yield. The isopropoxide groups are replaced with di(4-nitrophenyl)phosphate groups on treatment with the corresponding acid, and with chlorides on treatment with trimethylsilyl chloride. Metathesis with catechol leads to the bis(o-hydroxyphenoxide) complex rather than the chelating catecholate complex. Hydrolysis selectively gives the mu-oxo trimer (Delta,Delta,Delta)/(Lambda,Lambda,Lambda)-{(Fc(2)Bob)Ti(mu-O)}(3). The solid-state structures of the mu-oxo trimer and the bis(o-hydroxyphenoxide) complex show that the ferrocene substituents are oriented proximal to the biphenyl backbone rather than pointed out toward the exogenous groups. The complexes show dramatic changes in color depending on the bound anions, ranging from the red isopropoxide (lambda(max) = 489 nm) to the green bis(di(4-nitrophenyl)phosphate) (lambda(max) = 653 nm). The oxidation potentials of the ferrocenes show modest shifts based on the titanium environment, but the redox potentials of the two ferrocenes are never separated by more than 60 mV. These results and those of density-functional theory (DFT) calculations indicate that the titanium interacts principally with the lowest unoccupied molecular orbital (LUMO) of the ferrocenyldiketonate and very little with its highest occupied molecular orbital (HOMO).

  14. Search for alpha variation in UVES spectra: Analysis of C IV and Si IV doublets towards QSO 1101-264

    Science.gov (United States)

    Martínez Fiorenzano, A. F.; Vladilo, G.; Bonifacio, P.

    Motivated by previous studies of QSO spectra that reported a variation of the fine structure constant alpha , a search for C IV and Si IV doublets was conducted in the absorption spectrum toward QSO 1101-264, obtained by VLT-UVES during the Science Verification. Seven C IV and two Si IV systems were identified and accurate measurements of wavelengths over the redshift range 1.1862 < z < 1.8377 were performed. After a careful selection of pairs of lines, the ``Alkali Doublet" method with a derived analitical expression for the error analysis was applied to compute the alpha variation. The result according in magnitud order with previous doublets measurements, corresponds to one Si IV system: Delta alpha /alpha = (- 3.09 +/- 8.46) x 10-5. Data from UVES-VLT.

  15. Search for alpha variation in UVES spectra: Analysis of C IV and Si IV doublets towards QSO 1101-264

    CERN Document Server

    Fiorenzano, A F M; Bonifacio, P

    2003-01-01

    Motivated by previous studies of QSO spectra that reported a variation of the fine structure constant alpha, a search for C IV and Si IV doublets was conducted in the absorption spectrum towardS QSO 1101-264, obtained by VLT-UVES during the Science Verification. Seven C IV and two Si IV systems were identified and accurate measurements of wavelengths over the redshift range 1.1862 < z < 1.8377 were performed. After a careful selection of pairs of lines, the "Alkali Doublet" method with a derived analitical expression for the error analysis was applied to compute the alpha variation. The result according in magnitud order with previous doublets measurements, corresponds to one Si IV system: Delta alpha/alpha = (- 3.09 +/- 8.46) x 10^(-5).

  16. APLICACIÓN DE LA TECNICA DE IV GAMA PARA LA ELABORACIÓN DE ENSALADAS EVALUATION OF IV GAMA TECHNIQUE TO PREPARE VEGETABLE SALADS

    Directory of Open Access Journals (Sweden)

    Auris Damely García Méndez

    2008-12-01

    Full Text Available El propósito de la aplicación de la técnica de IV Gama en la elaboración de ensaladas listas para el consumo fresco, esta dirigido al control del deterioro en lechuga americana (Lactuca sativa, zanahoria (Daucus carota L., radicchio (Cichorium intybus L. y escarola (Cichorium endivia L., destinadas a preparar ensaladas tipo “Mediterránea y Cheff”. La metodología permitió seleccionar y evaluar la técnica de IV Gama, así como las buenas prácticas de manufactura para extender la vida comercial de las ensaladas y garantizar la seguridad alimentaria para la población potencialmente consumidora. La aplicación combinada de soluciones de cloruro de calcio al 1%, acido cítrico a 0,1% y oxido de magnesio al 0,5% contribuyo a mantener la calidad de las ensaladas por un período de 16 días bajo refrigeración a 5 + 1 °C y 95 + 5% HR. En conclusión las técnicas ensayadas, posibilitaron extender el valor comercial de estos productos.The purpose of applying the fresh-cut technique in preparing vegetable salads ready for fresh consumption, was aimed to control the damage American lettuce (Lactuca sativa; carrot (Daucus carota L; Radicchio (Cichorium intybus L and endive (Cichorium endivia L.“ Mediterranean and Cheff” style salads were prepared for evaluation. The methodology allowed selecting and evaluating fresh-cut technique as well as good manufacturing practices, to extend the commercial life, and guarantee alimentary food safety to people. Use of 1% calcium chloride; 0.1% citric acid and 0.5% magnesium oxide solutions; allowed to maintain the quality of the salads for a period of 16 up to days, under refrigeration at 5± 1ºC and 95 ± 5 % RH. Finally the assays techniques let to extend the commercial value of these vegetables.

  17. Structure activity relationship modelling of milk protein-derived peptides with dipeptidyl peptidase IV (DPP-IV) inhibitory activity.

    Science.gov (United States)

    Nongonierma, Alice B; FitzGerald, Richard J

    2016-05-01

    Quantitative structure activity type models were developed in an attempt to predict the key features of peptide sequences having dipeptidyl peptidase IV (DPP-IV) inhibitory activity. The models were then employed to help predict the potential of peptides, which are currently reported in the literature to be present in the intestinal tract of humans following milk/dairy product ingestion, to act as inhibitors of DPP-IV. Two models (z- and v-scale) for short (2-5 amino acid residues) bovine milk peptides, behaving as competitive inhibitors of DPP-IV, were developed. The z- and the v-scale models (p<0.05, R(2) of 0.829 and 0.815, respectively) were then applied to 56 milk protein-derived peptides previously reported in the literature to be found in the intestinal tract of humans which possessed a structural feature of DPP-IV inhibitory peptides (P at the N2 position). Ten of these peptides were synthetized and tested for their in vitro DPP-IV inhibitory properties. There was no agreement between the predicted and experimentally determined DPP-IV half maximal inhibitory concentrations (IC50) for the competitive peptide inhibitors. However, the ranking for DPP-IV inhibitory potency of the competitive peptide inhibitors was conserved. Furthermore, potent in vitro DPP-IV inhibitory activity was observed with two peptides, LPVPQ (IC50=43.8±8.8μM) and IPM (IC50=69.5±8.7μM). Peptides present within the gastrointestinal tract of human may have promise for the development of natural DPP-IV inhibitors for the management of serum glucose.

  18. Studies of obtaining and stability in aqueous medium of new complex compounds of Ti(IV) and Zr(IV) used in ecological leather tanning

    Science.gov (United States)

    Crudu, Marian; Sibiescu, Doina; Rosca, Ioan; Sutiman, Daniel; Vizitiu, Mihaela

    2009-01-01

    In this paper, the study of obtaining new coordination compounds of Ti(IV) and Zr(IV) using as ligand: D,L-β-iso-butyric acid, is presented. Also, the stability of these compounds in aqueous medium is studied. The studies of obtaining and of stability of the new compounds were accomplished in aqueous solutions using methods characteristic for coordination compounds: conductance and pH measurements. The combination ratios and the stability were determined with methods characteristic for studies in solutions. From experimental data resulted that the combination ratio of central metallic atoms with the ligand derived from D,L-β-iso-butyric acid was 1:2. From experimental data resulted that in strong acid and strong basic mediums, the coordination compounds could not be obtained. The optimal stability of the studied compounds is limited between 3-6, pH - values. This fact is in accordance with the conditions of using these compounds in ecological leather tanning. Of great importance is that these compounds were used with very good results in tanning processes of different types of leather. This fact evidenced that the ecological alternative of tanning is better than non-ecological tanning using chrome compounds. The importance of this paper consists in obtaining new coordination compounds that can be used in ecological leather tanning.

  19. Arquétipos da dualidade feminina no conto “Desenredo” de João Guimarães Rosa = Archetypes of feminine dualism in the short-story “Desenredo” by João Guimarães Rosa

    Directory of Open Access Journals (Sweden)

    Silva, Antonia Marly Moura da

    2012-01-01

    Full Text Available No conto “Desenredo”, integrante de Tutaméia (1967 de João Guimarães Rosa, os arquétipos da dualidade feminina emblematizam os atributos do posicionamento da mulher frente ao mundo. Adúltera, a personagem central é a Bruxa, a Grande prostituta, Lilith, encarnando a alma bacante, o protótipo dionisíaco, porém, no desfecho da narrativa, de forma mágica o amante consegue recompor aos olhos dos outros a imagem da mulher, temida e odiada pelos moradores do lugar. Reintegrando o arquétipo da Grande Mãe, a personagem passa a ser retratada como a Virgem, o arquétipo de Eva, representando a perfeição e a pureza: metas da aspiração masculina reconhecidas pela tradição de Eros. É, pois, seguindo essa linha de reflexão que faremos uma leitura do referido conto procurando reconhecer símbolos e arquétipos da dualidade expressos na arquitetura ficcional

  20. Implications of oxidovanadium(IV) binding to actin.

    Science.gov (United States)

    Ramos, Susana; Almeida, Rui M; Moura, José J G; Aureliano, Manuel

    2011-06-01

    Oxidovanadium(IV), a cationic species (VO(2+)) of vanadium(IV), binds to several proteins, including actin. Upon titration with oxidovanadium(IV), approximately 100% quenching of the intrinsic fluorescence of monomeric actin purified from rabbit skeletal muscle (G-actin) was observed, with a V(50) of 131 μM, whereas for the polymerized form of actin (F-actin) 75% of quenching was obtained and a V(50) value of 320 μM. Stern-Volmer plots were used to estimate an oxidovanadium(IV)-actin dissociation constant, with K(d) of 8.2 μM and 64.1 μM VOSO(4), for G-actin and F-actin, respectively. These studies reveal the presence of a high affinity binding site for oxidovanadium(IV) in actin, producing local conformational changes near the tryptophans most accessible to water in the three-dimensional structure of actin. The actin conformational changes, also confirmed by (1)H NMR, are accompanied by changes in G-actin hydrophobic surface, but not in F-actin. The (1)H NMR spectra of G-actin treated with oxidovanadium(IV) clearly indicates changes in the resonances ascribed to methyl group and aliphatic regions as well as to aromatics and peptide-bond amide region. In parallel, it was verified that oxidovanadium(IV) prevents the G-actin polymerization into F-actin. In the 0-200 μM range, VOSO(4) inhibits 40% of the extent of polymerization with an IC(50) of 15.1 μM, whereas 500 μM VOSO(4) totally suppresses actin polymerization. The data strongly suggest that oxidovanadium(IV) binds to actin at specific binding sites preventing actin polymerization. By affecting actin structure and function, oxidovanadium(IV) might be responsible for many cellular effects described for vanadium.

  1. Tin(IV) and lead(IV) complexes with a tetradentate redox-active ligand.

    Science.gov (United States)

    Piskunov, Alexandr V; Trofimova, Olesya Yu; Fukin, Georgy K; Ketkov, Sergei Yu; Smolyaninov, Ivan V; Cherkasov, Vladimir K

    2012-08-28

    The coordination chemistry of a tetradentate redox-active ligand, glyoxal-bis(2-hydroxy-3,5-di-tert-butylanil) (H(2)L), was investigated with the diorganotin(IV) and diphenyllead(IV) moieties. Complexes R(2)SnL (R = Me (1), Et (2), (t)Bu (3), Ph (4)) and Ph(2)PbL (5) have been prepared and characterized. The molecular structures of compounds 1, 3, and 5 have been determined by single crystal X-ray diffraction. The diamagnetic octahedral complexes bear a tetradentate O,N,N,O redox-active ligand with a nearly planar core. Complexes 1-5 demonstrate solvatochromism in solution. The CV of complexes 1-5 reveals four one-electron redox processes. The spin density distribution in the chemically generated cations and anions of 1-5 was studied by X-band EPR spectroscopy. The experimental data agree well with the results of DFT calculations of electronic structures for 1, its pyridine adduct 1·Py, cation 1(+) and anion 1(-).

  2. Metodología y clasificación de tipos de paisaje en Galicia

    Directory of Open Access Journals (Sweden)

    Augusto Pérez-Alberti

    2014-12-01

    Full Text Available En el presente artículo se exponen los resultados de las investigaciones llevadas a cabo con el fin de caracterizar los diferentes tipos de paisaje existentes en Galicia (Noroeste de España. Se ha considerado el paisaje como resultado de un sistema dinámico en que interaccionan elementos estructurales y texturales. El resultado ha sido la caracterización de 6 grupos de paisaje, en función del dominio de la dinámica natural o antrópica y 28 tipos de paisaje sobre los que incidir de forma directa de cara a su protección, gestión y ordenación.

  3. Papel da vitamina D na susceptibilidade para a diabetes mellitus tipo 1

    OpenAIRE

    2010-01-01

    A diabetes mellitus tipo 1 é uma doença crónica auto-imune, caracterizada pela destruição selectiva das células nos ilhéus pancreáticos, resultando numa perda lenta e progressiva da secreção de insulina e para a qual contribuem factores ambientais e factores de predisposição genética. Vários estudos epidemiológicos e experimentais sugerem que a vitamina D tem um efeito protector contra o desenvolvimento da diabetes mellitus tipo 1, através da modulação da resposta do siste...

  4. Aposentadoria e as mudanças de vida das pessoas com diabetes tipo 2

    OpenAIRE

    Ma. Laura Ruiz Paloalto

    2007-01-01

    Trata-se de um estudo qualitativo, que teve como objetivo compreender as mudanças de vida das pessoas aposentadas com diabete tipo 2. Primeiramente se caracteriza a população com diabetes tipo 2 da Clínica Hospital ISSSTE Celaya - México, onde extraiu-se uma amostra de 56 pacientes do quais 39,28% estão entre 60 e 69 anos de idade, 53,6% pertencem ao sexo feminino, 69,6% são casados, 35,7% são do lar, 41% têm nível básico de estudos, 92,8% vivem com algum familiar, 28,57% têm entre 1 e 5 anos...

  5. Long-Term IQ Stability Using the WISC-IV and WAIS-IV among a Sample of Special Education Students

    Science.gov (United States)

    Spector, Hayley

    2013-01-01

    The present study investigated the stability of scores on the WISC-IV and WAIS-IV over an approximate six-year period. Previous research using older versions of the WISC and WAIS have suggested that these scales demonstrate strong stability of scores. Since research that has compared the stability of scores between the WISC-IV and the WAIS-IV is…

  6. 78 FR 21491 - DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P.; Notice Seeking Exemption...

    Science.gov (United States)

    2013-04-10

    ... ADMINISTRATION DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that DeltaPoint Capital IV, L.P. and DeltaPoint Capital IV (New York), L.P., 45 East Avenue, 6th...

  7. Type IV collagen-degrading enzyme activity in human serum.

    OpenAIRE

    Hashimoto, Noriaki; Kobayashi, Michio; Watanabe,Akiharu; Higashi, Toshiro; Tsuji, Takao

    1988-01-01

    Type IV collagen-degrading enzyme activity was detected in human serum. Serum was preincubated with 4-aminophenylmercuric acetate and trypsin to activate the enzyme prior to assay. Type IV collagen, purified from human placentas and radiolabeled with [1-14C] acetic anhydride, was used as the substrate. The enzyme activity was measured at pH 7.5 and inhibited by treatment with ethylenediaminetetraacetic acid or heat. The assay of type IV collagen-degrading enzyme in human serum might be useful...

  8. A case of hereditary sensory autonomic neuropathy type IV

    Directory of Open Access Journals (Sweden)

    G P Prashanth

    2012-01-01

    Full Text Available Hereditary sensory autonomic neuropathy type IV (HSAN -IV, also known as congenital insensitivity to pain with anhidrosis, is a very rare condition that presents in infancy with anhidrosis, absence of pain sensation and self -mutilation. Developmental delay and mental retardation are usually present. Ultrastructural study of the peripheral nerves demonstrates loss of the unmyelinated and small myelinated fibers. We here report a 8 year -old boy with HSAN IV with typical clinical features where the diagnosis was supported by nerve biopsy findings. However, our case was unusual since mental development was normal.

  9. Distribución de marcadores discursivos en distintos tipos de discurso

    Directory of Open Access Journals (Sweden)

    María Teresa Poblete Bennett

    1999-09-01

    Full Text Available Partiendo de supuestos de Bolívar (1995, se establece que la entrevista semiformal es una clase de texto donde se dan distintos tipos de discurso, y se comprueba la ocurrencia de tres clases de marcadores discursivo-conversacionales en distintos tipos de discurso: expositivo, narrativo y argumentativo. El corpus analizado se obtuvo de dieciocho entrevistas, nueve hombres y nueve mujeres, divididas en tres estratos sociales y tres grupos etarios que conforman una muestra representativa de los hablantes de Valdivia urbano (Cepeda et al., 1988:56-66. Los resultados indican, por una parte, que la distribución de los relacionantes supraoracionales está condicionada por el tipo de discurso donde ocurren y al cual le contribuyen en el logro de su objetivo comunicativo básico. Por otra parte, la distribución de los marcadores interactivos y de modalidad covaría más con las variables sociales que con el tipo de discurso en que ocurren. (Bolívar's (1995 assumptions concerning kinds of texts and types of discourse have been taken into account for the study of the distribution of three groups of discourse markers in three types of discourse: expository, narrative and argumentative.The data was taken from 18 semiformal interviews to nine women and nine men divided according to social strata, sex and age who belong to a representative sample of Valdivian speakers (Cepeda, et al., 1988: 55-66. The results show, on the one hand, that the distribution of suprasentential connectors is conditioned by the type of discourse where they occur, and that this distribution contributes to the achievement of the communicative objective of each type of discourse. On the other hand, the distribution of interactive and modality markers varies according to social variables rather than the type of discourse where they occur.

  10. Los diferentes tipos de hidroxiapatita y sus aplicaciones en cirugía bucal

    OpenAIRE

    Sánchez Garcés, Ma. Ángeles; Berini Aytés, Leonardo; Gay Escoda, Cosme

    1993-01-01

    Se describe las aplicaciones actuales de los diferentes tipos de hidroxiapatita en las técnicas quirúrgicas bucales practicadas con anestesia local que consisten en técnicas de tunelización subperióstica y el relleno de los defectos óseos y su aplicación combinada con implantes endo-óseos y las membranas de regeneración tisular guiada.

  11. Nuovi approcci terapici in modelli murini di neurodegenerazione di tipo Alzheimer

    OpenAIRE

    Kleiner, Giulio

    1982-01-01

    La demenza di tipo Alzheimer (AD) rappresenta una delle principali patologie che affliggono la nostra società. Purtroppo, i trattamenti terapeutici oggi disponibili non sono in grado di bloccare l’inesorabile esito della malattia, ma solo di rallentarlo. Pertanto, lo studio di nuove strategie terapiche e la successiva validazione delle stesse sono obiettivi prioritari della ricerca, con robuste analisi da effettuare su modelli animali affidabili. Attualmente, nessuno dei modelli sperimentali ...

  12. Tipos de edentulismo parcial tratados con prótesis parcial removible

    OpenAIRE

    Nogueras Clemente, Joaquin; Vela, X.; Samsó Manzanedo, Jorge; Peraire Ardèvol, Maria; Anglada Cantarell, José María; Salsench Cabré, Juan

    1994-01-01

    Nuestro estudio se ha llevado a cabo sobre una muestra compuesta por 60 modelos para la confección de una PPR, en los cuales estudiamos las ausencias dentales y la clasificación según el tipo de edentación. Las ausencias dentales son el 45,6% del total y la clase I de Kennedy predomina en la arcada inferior, mientras que la clase II lo hace en la superior.

  13. Inibidores da fosfodiesterase do tipo 5 e perda auditiva neurossensorial súbita

    Directory of Open Access Journals (Sweden)

    Monique Antunes de Souza Chelminski Barreto

    2013-12-01

    Full Text Available O uso de inibidores da fosfodiesterase do tipo 5 como sildenafil, vardenafil e tadalafil tem aumentado atualmente e alguns destes pacientes vêm apresentando perda auditiva neurossensorial súbita. OBJETIVO: Apresentar dois casos de pacientes que apresentaram surdez súbita em uso eventual do medicamento e revisar estudos sobre o uso de inibidores da fosfodiesterase do tipo 5 e surdez súbita. MÉTODO: Estudo analítico de dois casos e revisão sobre o tema no banco de dados da Pubmed/ MedLine e Bireme utilizando as palavras-chave inibidores da fosfodiesterase e surdez súbita e seus correlatos na língua inglesa. RESULTADOS: Os pacientes analisados são jovens, sem comorbidades, em uso de inibidores da fosfodiesterase do tipo 5 e após terapia combinada para o tratamento da surdez súbita, apenas um deles obteve melhora auditiva. Nove estudos científicos foram encontrados. Estudos pré-clínicos e clínicos, transversais e prospectivos foram revisados. CONCLUSÃO: O aumento da ocorrência na prática clínica e relatos científicos na literatura sugerem que o uso de inibidores da fosfodiesterase do tipo 5 seja encarado como fator de risco para surdez súbita. Novos estudos com amostras maiores e grupo controle são necessários para investigar esta associação.

  14. Sobre el buen planteamiento de una ecuación del tipo r-BO bidimensional

    OpenAIRE

    2015-01-01

    En este trabajo tratamos el buen planteamiento en los espacios de Sobolev Hs (R2) del problema de Cauchy asociado a la ecuación del tipo r-BO bidimensional [Fórmula Matemátiva] donde u(x, y, t) es real si x, y, t ∈ R. También, estableceremos resultados sobre la continuación única, para esta ecuación.

  15. PREJUÍZOS COGNITIVOS EM IDOSOS COM DIABETES MELLITUS TIPO 2

    Directory of Open Access Journals (Sweden)

    Regina Maria Fernandes Lopes

    2009-01-01

    Full Text Available El avance en las condiciones de salud propicia el progresivo aumento de la esperanza de vida. Estudios han identificado la existencia de una conexión entre la Diabetes Mellitus (DM y demencia. La hiperglicemia podría ser un factor importante en la incidencia de la enfermedad de Azheimer, la cual puede ser una causa secundaria de demencia. La diabetes mellitus tipo 2 (DM2 está asociada con déficits cognitivos y funcionales, y el WCST es una de las herramientas que puede ser utilizada para evaluar funcionamiento ejecutivo. El objetivo de este estudio fue evaluar los déficits cognitivos de ancianos con diabetes mellitus tipo 2. Los participantes fueron 254 ancianos de ambos sexos, mayores de 60 años; 44 de ellos diagnosticados de DM2 y 210 en un grupo control de población general. El diseño fue un estudio cuantitativo transversal. Los instrumentos utilizados fueron: datos sociodemográficos, WCST, MMSE, BDI, BAI, GD, junto a las Sub pruebas de: Vocabulario, códigos, números y Cubos del WAIS-III. Los resultados mostraron una diferencia significativa en el desempeño de los ancianos con diabetes tipo 2 en comparación con el grupo control en cuatro descriptores de WCST que indicaban un deterioro. Igualmente los ancianos con diabetes tipo 2 mostraron una intensidad de síntomas depresivos y de ansiedad estadísticamente mayor que el grupo control

  16. Compactones, soluciones de ecuaciones no lineales con estructura tipo esferas duras

    Directory of Open Access Journals (Sweden)

    Máximo Agüero Granados

    2001-01-01

    Full Text Available Se estudian ciertas soluciones de ecuaciones no lineales que modelan procesos físicos, que tienen semejanzas con estructuras coherentes del tipo de esferas duras, modelo de partículas muy usado en varias ramas de la física. Estas soluciones compactas (gotas, kinks, etcétera. interactúan entre sí sólo a cortas distancias, porque no poseen colas infinitas como los solitones clásicos.

  17. Epidemiología de la diabetes mellitus en la infancia y adolescencia: tipo 1, tipo 2 y ¿diabetes "doble"?

    Directory of Open Access Journals (Sweden)

    Ingrid M. Libman

    2009-09-01

    Full Text Available Durante las últimas décadas, el aporte de la epidemiología a través de la estandarización de los métodos y las definiciones y la colaboración internacional ha permitido una mejor estimación de la incidencia y prevalencia de la diabetes mellitus (DM en la infancia y la adolescencia, así como la detección de probables factores de riesgo para los distintos tipos de la enfermedad, lo que orientaría al desarrollo de medidas preventivas y terapéuticas y la mayor comprensión de la magnitud del problema. Se ha observado un aumento global y amplias diferencias entre distintas regiones en la incidencia de la diabetes tipo 1 (DM1, al igual que un incremento en la frecuencia de la diabetes tipo 2 (DM2 en ciertas etnias asociado a un aumento de la obesidad. Se ha descripto la existencia de la llamada DM "doble" o "híbrida", caracterizada por la asociación de un fenotipo de DM2 (obesidad, acantosis nigricans con manifestaciones de autoinmunidad anti células beta.During the last decades, the contribution of epidemiology through the standardization of methods and definitions and international collaboration allowed a better estimation of the incidence and prevalence of DM in children and adolescents, as well as the detection of likely risk factors for the different types of the disease, which would allow the development of preventive and therapeutic measures and a better understanding of the magnitude of the problem. A global increase and wide differences in the incidence of type 1 diabetes have been observed among regions, as well as an increase in the frequency of type 2 diabetes in some ethnic groups, associated to a growing prevalence of obesity. The existence of what has been named "double" or "hybrid" DM has also been described, characterized by a phenotype of DM2 (obesity and acantosis nigricans associated with manifestations of autoimmunity.

  18. El automanejo de los pacientes con diabetes tipo 2: una revisión narrativa

    Directory of Open Access Journals (Sweden)

    N. Campo Guinea

    2013-12-01

    Full Text Available Según la Organización Mundial de la Salud para el año 2030 la cifra de personas con diabetes mellitus alcanzará valores cercanos a 366 millones en el mundo, ocupando su mayor proporción la diabetes mellitus tipo 2. Las estrategias actuales de Cronicidad y de la Diabetes presentes en España abogan por un adecuado automanejo del paciente por medio de programas y/o intervenciones apropiadas para ello. Sin embargo, existen unos conocimientos y actitudes inadecuadas que limitan la asociación paciente-profesional que las estrategias de automanejo implican. A través de esta revisión bibliográfica se pretende mostrar las necesidades reales no cubiertas que los pacientes con diabetes mellitus tipo 2 tienen a la hora de automanejar la enfermedad. Así, se asentarán las bases para el desarrollo de futuros programas efectivos que se implementen ayudando al profesional sanitario a dirigir su trabajo diario hacía su principal objetivo, la persona con diabetes mellitus tipo 2 y sus necesidades.

  19. Determinantes del tipo de cambio real en Colombia. Un modelo neokeynesiano

    Directory of Open Access Journals (Sweden)

    Moreno Rivas, Álvaro Martín

    2002-12-01

    Full Text Available Este artículo presenta un modelo de tipo de cambio real siguiendo los desarrollos de la escuela neokeynesiana. Se estima econométricamente de acuerdo con la metodología de la escuela inglesa de econometría. El modelo empírico incorpora una dinámica interesante y respeta las restricciones de equilibrio de largo plazo entre el tipo de cambio real y los fundamentales macroeconómicos. Se encuentra que el ritmo de apreciación o depreciación del tipo de cambio real está determinado por los cambios en los términos de intercambio, la apertura de la economía, los flujos de capitales y la aceleración de la devaluación nominal. El incremento del gasto público no es significativo a los niveles convencionales de confianza estadística. Finalmente se evalúa si la devaluación cumple con los requisitos de exogeneidad débil, exogeneidad fuerte y superexogeneidad.

  20. Tipos de Ativismo Digital e Ativismo Preguiçoso no Mapa Cultural

    Directory of Open Access Journals (Sweden)

    Gabriela Bezerra Lima

    2012-08-01

    Full Text Available Este artigo se propõe a elencar os tipos de ativismo digital desenvolvidos por instituições e indivíduos e que estimulam o compartilhamento de suas mensagens nas redes sociais digitais. A partir da classificação dos tipos de ativismo digital (VEGH, 2003, propomos uma subclassificação do ativismo de ‘organização e mobilização’ e das ações de “ativismo preguiçoso” (MOROZOV, 2010 dos internautas. Para exemplificar os tipos de ativismo digital, este artigo observa as ações desenvolvidas na internet pela Fundação SOS Mata Atlântica. Nosso objetivo é analisar como os contratos de comunicação (CHARAUDEAU, 2006 de ativismo digital são percebidos e quais são seus níveis de contestação ao status quo no Mapa Cultural (DOUGLAS, 1998.

  1. Efecto incretina en el tratamiento de la diabetes mellitus tipo 2

    Directory of Open Access Journals (Sweden)

    Manuel de Jesús Díaz Pérez

    2015-02-01

    Full Text Available El efecto incretina está dado por las funciones del polipéptido insulinotrópico dependiente de glucosa y un péptido similar a glucagón sobre la hiperglucemia en el organismo humano. Desde su descubrimiento ha cobrado un papel cada vez más significativo en la elaboración de nuevos fármacos normoglucemiantes, que logren el control metabólico de los pacientes con diabetes mellitus tipo 2. El objetivo de esta revisión es actualizar la información sobre el efecto incretina, su relación con la diabetes mellitus tipo 2, los fármacos cuyo mecanismo de acción se basa en este fenómeno fisiológico, así como las perspectivas para el futuro inmediato en este tema. Para ello se realizó una revisión bibliográfica, empleando servicios disponibles desde la red Infomed, específicamente: SciELO, Hinari, PubMed y EBSCO. Se resumen aspectos del sustrato fisiológico y fisiopatológico del efecto incretina y su aplicación en la terapéutica de los pacientes con diabetes mellitus tipo 2, así como los resultados positivos que se han logrado hasta el momento en este campo

  2. RELACIÓN ENTRE EL TIPO DE APOYO Y EL ESTILO DE AMOR EN PAREJAS

    Directory of Open Access Journals (Sweden)

    Sergio Daniel Solares Barbosa

    2011-01-01

    Full Text Available Debido al incremento en el índice de divorcios en México, esta investigación tuvo como objetivo determinar la relación que existe entre el tipo de apoyo y el estilo de amor en parejas casadas mediante la aplicación del Inventario de Estilos de Amor y el Cuestionario de Tipo de Apoyo en Parejas. Se realizó una correlación de Pearson entre los estilos de amor y los tipos de apoyo, hallándose que el estilo de amor amistoso se presenta con mayor frecuencia y tiene una relación positiva con el apoyo expresado, mientras que el amor lúdico es menos frecuente y se vincula con el apoyo negativo. Para las mujeres es muy importante que exista un sentimiento de amistad para percibir un apoyo positivo de la pareja, mientras que en los hombres la relación pasional es aquella en la que se percibe el apoyo. En hombres y mujeres el estilo de amor lúdico es el que menos apoyo positivo encuentra.

  3. 21 CFR 1306.27 - Provision of prescription information between retail pharmacies and central fill pharmacies for...

    Science.gov (United States)

    2010-04-01

    ... retail pharmacy pharmacist transmitting the prescription, and the date of transmittal; (2) Ensure that... retail pharmacies and central fill pharmacies for initial and refill prescriptions of Schedule III, IV... Provision of prescription information between retail pharmacies and central fill pharmacies for initial...

  4. Fire retardancy of emulsion polymerized poly (methyl methacrylate)/cerium(IV) dioxide and polystyrene/cerium(IV) dioxide nanocomposites

    Energy Technology Data Exchange (ETDEWEB)

    Cai, Guipeng [Department of Chemistry and Fire Retardant Research Facility, Marquette University, PO Box 1881, Milwaukee, WI 53201 (United States); Lu, Hongdian [Department of Chemical and Materials Engineering, Hefei University, Hefei, Anhui 230022 (China); Zhou, You; Hao, Jianwei [School of Material Science and Engineering, Beijing Institute of Technology, Beijing 100081 (China); Wilkie, Charles A., E-mail: charles.wilkie@marquette.edu [Department of Chemistry and Fire Retardant Research Facility, Marquette University, PO Box 1881, Milwaukee, WI 53201 (United States)

    2012-12-10

    Highlights: Black-Right-Pointing-Pointer We prepare PMMA and PS containing ceria. Black-Right-Pointing-Pointer Characterization by XRD and TEM shows that some of the ceria is well-dispersed in the polymers. Black-Right-Pointing-Pointer The addition of ceria to both polymers leads to reduced thermal stability. Black-Right-Pointing-Pointer In PMMA, the fire retardancy is enhanced but there is little effect in PS. - Abstract: In situ emulsion polymerization was employed to obtain poly (methyl methacrylate) (PMMA)/cerium(IV) dioxide and polystyrene (PS)/cerium(IV) dioxide nanocomposites at two different cerium(IV) dioxide loadings (2.3 wt% and 4.6 wt%). Transmission electron microscope results indicated uniform dispersion of cerium (IV) dioxide in the polymer matrix. Both PMMA and PS nanocomposites exhibit lower thermal stability than the pristine polymers. Microscale combustion calorimeter (MCC) and cone calorimetry are used to evaluate the fire retardancy of the polymer nanocomposites. PMMA/cerium(IV) dioxide showed significant heat release rate (HRR) reduction at low loadings (<5 wt%), while PS/cerium(IV) dioxide exhibits less HRR reduction at the same loadings. An explanation of the role of cerium (IV) dioxide in fire retardancy of polymer/ceria nanocomposites based on XPS results is suggested.

  5. Identificação molecular de Mycoplasma mycoides subesp. mycoides tipo SC ioslado do conduto auditivo externo de caprinos clinicamente saudáveis

    Directory of Open Access Journals (Sweden)

    Pereira Lucieri Olegário

    2003-01-01

    Full Text Available O trabalho relata a presença de Mycoplasma mycoides subesp. mycoides Tipo SC, biótipo bovino, em caprinos clinicamente saudáveis no Estado do Rio de Janeiro, Brasil, identificado por PCR.

  6. A barium-rich binary central star in Abell 70

    CERN Document Server

    Boffin, Henri M J; Frew, D J; Acker, A; Köppen, J; Moffat, A F J; Parker, Q A

    2011-01-01

    We have found the central star of Abell 70 (PN G038.1-25.4, hereafter A 70) to be a binary consisting of a G8 IV-V secondary and a hot white dwarf. The secondary shows enhanced Ba II and Sr II features, firmly classifying it as a barium star. The nebula is found to have Type-I chemical abundances with helium and nitrogen enrichment, which combined with future abundance studies of the central star, will establish A 70 as a unique laboratory for studying s-process AGB nucleosynthesis.

  7. Risco de tração excessiva nas lesões tipo distração-flexão da coluna cervical baixa Risk of excessive traction on distraction-flexion-type injuries of the low cervical spine

    Directory of Open Access Journals (Sweden)

    Tarcísio Eloy Pessoa de Barros Filho

    2006-01-01

    Full Text Available O estudo em questão visa avaliar a relação entre risco e benefício do uso de tração com halo craniano como alternativa para estabilização nas fraturas-luxações por mecanismo de distração-flexão tipo IV de Allen e Ferguson, considerando a natureza da lesão, seu extenso dano ligamentar e o risco de apresentar distração excessiva e conseqüente lesão da medula espinhal. Para tanto, realizamos uma análise retrospectiva no IOT-HC-FMUSP envolvendo um período de 10 anos, quando 34 casos foram diagnosticados como fratura-luxação por distração-flexão da coluna cervical baixa, sendo 12 deles do tipo IV. Todos foram submetidos à tração esquelética com halo craniano num momento inicial. Durante o controle radiográfico seqüencial, observou-se distração excessiva em sete casos, mesmo com baixo peso inicial (4 kg. Em dois pacientes houve surgimento de nistagmo. Em todos os casos a tração foi retirada e seguiu-se normalização do quadro clínico.This study aims to evaluate the risk/ benefit ratio in the use of traction with cranial halo as an alternative to stabilize fractures-dislocations by Allen & Ferguson's type IV- distraction-flexion mechanism, considering the nature of the injury, its extensive ligament damage and the risk of presenting excessive distraction and resultant spinal cord injury. Thus, we performed a retrospective analysis at IOT-HC-FMUSP comprising a period of 10 years, when 34 cases were diagnosed as fractures-dislocations due to distraction-flexion of the low cervical spine, of which 12 were IV-type. All individuals have been submitted to skeletal traction with cranial halo at an early phase. During sequential X-ray management, an excessive distraction was seen in seven cases, even with initial light weight (4 kg. In two patients, the onset of nistagmus was seen. In all cases, traction was removed, which was followed by stabilization of the clinical picture.

  8. Efecto de los factores socioculturales en la capacidad de autocuidado del paciente hospitalizado con diabetes tipo 2

    OpenAIRE

    Mireya Gricelia Galindo-Martínez; Laura Rico-Herrera; Nicolás Padilla-Raygoza

    2014-01-01

    Introducción: la diabetes tipo 2 es considerada como un problema de salud pública por su creciente prevalencia e incidencia. Obje- tivo: describir el efecto de los factores socioculturales en la capacidad de autocuidado del paciente hospitalizado con diabetes tipo 2 en el Hospital General de Tecomán, Colima, México. Método: estudio transversal, observacional. Se trabajó con 68 pacientes hospitalizados con diabetes tipo 2; se utilizó un instrumento que midió el efecto de los factores sociocult...

  9. Lipoperóxidos, actividad antioxidante y factores prooxidantes en adultos mayores con diabetes mellitus tipo 2

    OpenAIRE

    Ricardo Blanco Hernández; Mirna Ruíz Ramos; Martha A. Sánchez Rodríguez; Víctor Manuel Mendoza Núñez

    2004-01-01

    Antecedentes: La diabetes mellitus tipo 2 (DM) es una enfermedad crónico-degenerativa de alta prevalencia durante el envejecimiento que ha sido asociada con el estrés oxidativo (EOx), sin embargo las evidencias científicas no son del todo concluyentes. Objetivo: Determinar la relación de los niveles plasmáticos de lipoperóxidos (LPO), actividad antioxidante y factores pro-oxidantes con la DM tipo 2 en adultos mayores. Material y métodos: Se llevó a cabo un estudio de tipo transversal, compara...

  10. Gestión del riesgo de tipo de cambio: caso de la inversión en bolsa

    OpenAIRE

    2014-01-01

    RESUMEN: El análisis y la gestión del riesgo de tipo de cambio es un aspecto muy importante a la hora de realizar operaciones en el exterior. Por ello, en el trabajo que se presenta a continuación estudiaremos desde un punto de vista teórico la evolución del sistema monetario internacional, así como la definición del tipo de cambio y del riesgo del tipo de cambio, englobados dentro del mercado de divisas. Además, propondremos alternativas para la cobertura de dicho riesgo: el forward y los co...

  11. Intensyviosios insulino terapijos naujovės gydant 1 ir 2 tipo cukrinį diabetą

    OpenAIRE

    Varanauskienė, Eglė; Čeponienė, Indrė; Čeponis, Jonas

    2006-01-01

    Sergančiųjų 1 ir 2 tipo cukriniu diabetu pagrindinis gydymo tikslas – pasiekti ir palaikyti gerą glikemijos kontrolę (glikuotas hemoglobinas – HbA1c≤7,0 proc. pagal ADA (angl. American Diabetes Association – Amerikos diabeto asociacija) ir ≤6,5 proc. pagal IDF (angl. International Diabetes Federation – Tarptautinė diabeto federacija) taip sumažinant cukrinio diabeto komplikacijų riziką. Insulinoterapija būtina sergantiesiems 1 tipo cukriniu diabetu. Sergančiųjų 2 tipo cukriniu diabetu gydymas...

  12. OS EFEITOS DO EXERCÍCIO AERÓBICO NO TRATAMENTO DO DIABETES MELLITUS TIPOS 1 E 2

    OpenAIRE

    da Silva Neto, João Henrique; Ex-aluno do Centro Universitário La Salle; Marques Toigo, Adriana

    2013-01-01

    O objetivo desse estudo foi revisar na literatura os efeitos do exercício aeróbico (especialmente na modalidade de dança) no tratamento do diabetes mellitus tipo 1 e tipo 2, apresentando resultados obtidos em pesquisa nacionais e internacionais. Inicialmente foram abordados aspectos conceituais sobre o diabetes mellitus tipos 1 e 2. Em seguida, verificou-se como o exercício aeróbico vem sendo utilizado como tratamento do diabetes e quais são seus benefícios em relação aos índices glicêmicos e...

  13. Epidemiología de la diabetes mellitus en la infancia y adolescencia: tipo 1, tipo 2 y ¿diabetes "doble"?

    OpenAIRE

    Libman, Ingrid M.

    2009-01-01

    Durante las últimas décadas, el aporte de la epidemiología a través de la estandarización de los métodos y las definiciones y la colaboración internacional ha permitido una mejor estimación de la incidencia y prevalencia de la diabetes mellitus (DM) en la infancia y la adolescencia, así como la detección de probables factores de riesgo para los distintos tipos de la enfermedad, lo que orientaría al desarrollo de medidas preventivas y terapéuticas y la mayor comprensión de la magnitud del prob...

  14. Relating binary-star planetary systems to central configurations

    CERN Document Server

    Veras, Dimitri

    2016-01-01

    Binary-star exoplanetary systems are now known to be common, for both wide and close binaries. However, their orbital evolution is generally unsolvable. Special cases of the N-body problem which are in fact completely solvable include dynamical architectures known as central configurations. Here, I utilize recent advances in our knowledge of central configurations to assess the plausibility of linking them to coplanar exoplanetary binary systems. By simply restricting constituent masses to be within stellar or substellar ranges characteristic of planetary systems, I find that (i) this constraint reduces by over 90 per cent the phase space in which central configurations may occur, (ii) both equal-mass and unequal-mass binary stars admit central configurations, (iii) these configurations effectively represent different geometrical extensions of the Sun-Jupiter-Trojan-like architecture, (iv) deviations from these geometries are no greater than ten degrees, and (v) the deviation increases as the substellar masse...

  15. Complexation of Plutonium (IV) With Sulfate At Variable Temperatures

    Energy Technology Data Exchange (ETDEWEB)

    Y. Xia; J.I. Friese; D.A> Moore; P.P. Bachelor; L. Rao

    2006-10-05

    The complexation of plutonium(IV) with sulfate at variable temperatures has been investigated by solvent extraction method. A NaBrO{sub 3} solution was used as holding oxidant to maintain the plutonium(IV) oxidation state throughout the experiments. The distribution ratio of Pu(IV) between the organic and aqueous phases was found to decrease as the concentrations of sulfate were increased. Stability constants of the 1:1 and 1:2 Pu(IV)-HSO{sub 4}{sup -} complexes, dominant in the aqueous phase, were calculated from the effect of [HSO{sub 4}{sup -}] on the distribution ratio. The enthalpy and entropy of complexation were calculated from the stability constants at different temperatures using the Van't Hoff equation.

  16. Platinum(iv) anticancer prodrugs - hypotheses and facts.

    Science.gov (United States)

    Gibson, Dan

    2016-08-16

    In this manuscript we focus on Pt(iv) anticancer prodrugs. We explore the main working hypotheses for the design of effective Pt(iv) prodrugs and note the exceptions to the common assumptions that are prevalent in the field. Special attention was devoted to the emerging class of "dual action" Pt(iv) prodrugs, where bioactive ligands are conjugated to the axial positions of platinum in order to obtain orthogonal or complementary effects that will increase the efficacy of killing the cancer cells. We discuss the rationale behind the design of the "dual action" prodrugs and the results of the pharmacological studies obtained. Simultaneous release of two bioactive moieties inside the cancer cells often triggers several processes that together determine the fate of the cell. Pt(iv) complexes provide many opportunities for applying new concepts in targeting, synergistic cell killing and exploiting novel nanodelivery systems.

  17. 75 FR 16445 - Defense Transportation Regulation, Part IV

    Science.gov (United States)

    2010-04-01

    ...--TSP Qualifications Attachment V.D--Rate Filing Attachment V.E--Customer Satisfaction Survey Attachment... Internet on the USTRANSCOM homepage at http:// ] www.transcom.mil/j5/pt/dtr_part_iv.cfm. Dated: March...

  18. Relación entre el Índice de Precios, la Tasa de Interés, el Tipo de Cambio Real y los Medios de Pago en Colombia, Durante 1970-2004

    Directory of Open Access Journals (Sweden)

    Luis Eduardo Sandoval

    2006-01-01

    Full Text Available La economía Colombiana ha sido manejada por diferentes tipos de cambio, debido a que el gobierno y sus instituciones han sufrido diversos cambios legislativos, que han llevado a la consolidación de un Banco Central independiente de las decisiones del Gobierno. El presente artículo busca analizar algunas variables monetarias que permitan brindar elementos de juicio para distinguir condiciones parciales, con las cuales se pueda lograr que se presente equilibrio entre los diferentes mercados participantes de la economía nacional.

  19. 77 FR 16508 - National Emission Standards for Hazardous Air Pollutant Emissions: Group IV Polymers and Resins...

    Science.gov (United States)

    2012-03-21

    ...: Group IV Polymers and Resins; Pesticide Active Ingredient Production; and Polyether Polyols Production... pollutants: National Emission Standards for Hazardous Air Pollutant Emissions: Group IV Polymers and Resins...: Group IV Polymers and Resins; Pesticide Active Ingredient Production; and Polyether Polyols...

  20. SOMATÓTIPO E IMAGEM CORPORAL EM PESSOAS VIVENDO COM HIV/AIDS

    Directory of Open Access Journals (Sweden)

    Danielle Coutinho de Medeiros

    2016-02-01

    Full Text Available RESUMO Introdução: A terapia antirretroviral de alta atividade (HAART está associada ao surgimento de diversos efeitos adversos na população com HIV/Aids, dentre as quais, a lipodistrofia. Caracterizada pela reorganização anormal de gordura pelo corpo, é um dos efeitos mais relevantes, envolvendo riscos cardiometabólicos e prejuízos na imagem corporal. Objetivo: Analisar a somatotipia e a imagem corporal em pessoas vivendo com HIV/AIDS. Métodos: A amostra foi composta por cinco mulheres (47,8 ± 6,53 anos em uso da HAART e fisicamente ativas. Foi realizada uma intervenção com o treinamento concorrente e aconselhamento dietético e avaliou-se a conformação corporal pelo somatótipo e a imagem corporal pela escala de silhuetas. Resultados: Não houve diferença na classificação do somatótipo, entretanto, os resultados apontaram diferença significativa para a análise da distância de dispersão entre somatótipos (DDS na 1ª semana (DDS = 2,63 e 16ª semana de intervenção (DDS = 2,96, quando avaliado pelas médias; e quando avaliado individualmente, verificou-se diferença significativa tanto na DDS quanto na distância espacial entre somatótipos (DES nos casos 1, na 8ª semana (DDS = 3,20 e DES = 1,01 e 16.a semana (DDS = 2,73; e caso 3, na 1ª semana (DDS = 9,25 e DES = 1,44 e 16ª semana (DDS = 8,06 e DES = 1,37. Quanto à imagem corporal, observou-se a aproximação da imagem atual à imagem ideal (imagem atual inicial = 6; imagem atual final = 5; e imagem ideal inicial e final = 3. Conclusão: O programa de treinamento concorrente associado à orientação nutricional produziu resultados positivos tanto no somatótipo quanto na percepção da imagem corporal das participantes, comprovando sua eficácia no controle da lipodistrofia e na satisfação da imagem corporal do grupo avaliado.

  1. Iværksætteri ved knopskydning

    DEFF Research Database (Denmark)

    Christensen, Poul Rind; Evald, Majbritt Rostgaard

    2007-01-01

    Artiklen ser nærmere på iværksætteri ved knopskydning - hvorfor knopskydning fra eksisterende virksomheder menes at give positive bidrag til vækst og overlevelse blandt iværksætterne blandt andet ved at se på internationale undersøgelser, der er foretaget af forskellige typer af knopskydning. Art....... Artiklen kaster lys over, hvor udbredt knopskydning er som kilde til virksomhedsetableringer i Danmark. Udgivelsesdato: 6/9...

  2. Nordic Nuclear Materials Forum for Generation IV Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Anghel, C. (Studsvik Nuclear AB, Nykoeping (Sweden)); Penttilae, S. (Technical Research Centre of Finland, VTT (Finland))

    2010-03-15

    A network for material issues for Generation IV nuclear power has been initiated within the Nordic countries. The objectives of the Generation IV Nordic Nuclear Materials Forum (NOMAGE4) are to put the basis of a sustainable forum for Gen IV issues, especially focussing on fuels, cladding, structural materials and coolant interaction. Other issues include reactor physics, dynamics and diagnostics, core and fuel design. The present report summarizes the work performed during the year 2009. The efforts made include identification of organisations involved in Gen IV issues in the Nordic countries, update of the forum website, http://www.studsvik.se/GenerationIV, and investigation of capabilities for research within the area of Gen IV. Within the NOMAGE4 project a seminar on Generation IV Nuclear Energy Systems has been organized during 15-16th of October 2009. The aim of the seminar was to provide a forum for exchange of information, discussion on future research needs and networking of experts on Generation IV reactor concepts. As an outcome of the NOMAGE4, a few collaboration project proposals have been prepared/planned in 2009. The network was welcomed by the European Commission and was mentioned as an exemplary network with representatives from industries, universities, power companies and research institutes. NOMAGE4 has been invited to participate to the 'European Energy Research Alliance, EERA, workshop for nuclear structural materials' http://www.eera-set.eu/index.php?index=41 as external observers. Future plans include a new Nordic application for continuation of NOMAGE4 network. (author)

  3. IV cannula securement: protecting the patient from infection.

    Science.gov (United States)

    Higgingson, Ray

    The use of venous cannulas to administer intravenous therapy is a common clinical intervention within the hospital setting. Once in situ, IV cannulas must be securely fixed in order to prevent their movement or displacement; as unsecured cannulas pose significant health risks, such as mechanical phlebitis and an increased risk of infection. This article explores some of the complications associated with inappropriately secured IV cannulas, along with a discussion on common securement devices.

  4. Central Laboratories Services

    Data.gov (United States)

    Federal Laboratory Consortium — The TVA Central Laboratories Services is a comprehensive technical support center, offering you a complete range of scientific, engineering, and technical services....

  5. Guía técnica de construcción y funcionamiento de secadoras solares tipo domo

    Directory of Open Access Journals (Sweden)

    Delmar Cruz

    2011-11-01

    Full Text Available El articulo “Secadoras solares tipo domo para café pergamino. La experiencia en Huehuetenengo, Guatemala C.A.” es una de las publicaciones técnicas elaborado por el Programa Café y Caffè con el objetivo de beneficiar a los técnicos, los productores de café de calidad y los operadores del sector del café. El Programa Red Regional para el apoyo a las Asociaciones de pequeños productores de café de la América Central y Caribe implica seis Países: Guatemala, República Dominicana, El Salvador, Honduras, Costa Rica y Nicaragua. Este Programa tiene por objetivo mejorar la calidad de vida de los pequeños productores de café de las comunidades rurales de Montaña y hacer sostenible el cultivo de café de calidad. El Programa cuenta con la financiación del gobierno de Italia a través de la Dirección General para la Cooperación al Desarrollo del Ministerio de Relaciones Exteriores y del “Common Fund for Commodities” (CFC, que designa como entitad para la supervisión técnica la “International Coffee Organization” (ICO. El Istituto Agronomico per l’Oltremare de Florencia (IAO es la institución principal responsable de la ejecución y la coordinación de las actividades que se realizan en colaboración con la Fundación Slow Food para la Biodiversidad e la Ong Italiana Ucodep.

  6. Psychological variables and Wechsler Adult Intelligence Scale-IV performance.

    Science.gov (United States)

    Gass, Carlton S; Gutierrez, Laura

    2016-06-07

    The MMPI-2 and WAIS-IV are commonly used together in neuropsychological evaluations yet little is known about their interrelationships. This study explored the potential influence of psychological factors on WAIS-IV performance in a sample of 180 predominantly male veteran referrals that underwent a comprehensive neuropsychological examination in a VA Medical Center. Exclusionary criteria included failed performance validity testing and self-report distortion on the MMPI-2. A Principal Components Analysis was performed on the 15 MMPI-2 content scales, yielding three broader higher-order psychological dimensions: Internalized Emotional Dysfunction (IED), Externalized Emotional Dysfunction (EED), and Fear. Level of IED was not related to performance on the WAIS-IV Full Scale IQ or its four indexes: (Verbal Comprehension, Perceptual Reasoning, Working Memory, and Processing Speed). EED was not related to WAIS-IV performance. Level of Fear, which encompasses health preoccupations (HEA) and distorted perceptions (BIZ), was significantly related to WAIS-IV Full Scale IQ and Verbal Comprehension. These results challenge the common use of high scores on the MMPI-2 IED measures (chiefly depression and anxiety) to explain deficient WAIS-IV performance. In addition, they provide impetus for further investigation of the relation between verbal intelligence and Fear.

  7. Dipeptidyl peptidase IV in two human glioma cell lines

    Directory of Open Access Journals (Sweden)

    A Sedo

    2009-12-01

    Full Text Available There is growing evidence that dipeptidyl peptidase IV [DPP-IV, EC 3.4.14.5] takes part in the metabolism of biologically active peptides participating in the regulation of growth and transformation of glial cells. However, the knowledge on the DPP-IV expression in human glial and glioma cells is still very limited. In this study, using histochemical and biochemical techniques, the DPP-IV activity was demonstrated in two commercially available human glioma cell lines of different transformation degree, as represented by U373 astrocytoma (Grade III and U87 glioblastoma multiforme (Grade IV lines. Higher total activity of the enzyme, as well as its preferential localisation in the plasma membrane, was observed in U87 cells. Compared to U373 population, U87 cells were morphologically more pleiomorphic, they were cycling at lower rate and expressing less Glial Fibrillary Acidic Protein. The data revealed positive correlation between the degree of transformation of cells and activity of DPP-IV. Great difference in expression of this enzyme, together with the phenotypic differences of cells, makes these lines a suitable standard model for further 57 studies of function of this enzyme in human glioma cells.

  8. Anti-Fibrotic Effects of Astragaloside IV in Systemic Sclerosis

    Directory of Open Access Journals (Sweden)

    Qing Qi

    2014-11-01

    Full Text Available Objective: To evaluate the anti-fibrotic effects of Astragaloside IV in systemic sclerosis. Methods: Treated or untreated systemic sclerosis (SSc and normal fibroblast isolated from corresponding pairs were utilized to detect expression of collagen and fibronectin by western blot, quantitative real-time RT-PCR (RT-qPCR, immunofluorescence staining and histopathological examination. SSc mouse model induced by bleomycin was used to evaluate the effects of the drug in vivo. Results: Compared to normal fibroblast (NF, the expression of collagen and fibronectin in SSc (SScF dramatically increased, and this could be reduced by Astragaloside IV (AST in a dose- or time-dependent manner at both protein and mRNA levels. Administration of Astragaloside IV consistently decreased collagen formation and partially restored the structure, as well as suppressing collagen and fibronectin expression in the skin lesions of SSc-model mice. Mechanistically, Astragaloside IV-induced fibrosis reduction may be due to deregulation of Smad 3/Fli-1, the major mediators of the fibrotic response and key molecules for TGF-β signaling. Astragaloside IV also decreased the level of p-SMAD3 and completely blocked its relocation into the nuclei. Conclusion: Astragaloside IV attenuates fibrosis by inhibiting the TGF-β-Smads3 axis in systemic sclerosis.

  9. Assembling filamentous phage occlude pIV channels.

    Science.gov (United States)

    Marciano, D K; Russel, M; Simon, S M

    2001-07-31

    Filamentous phage f1 is exported from its Escherichia coli host without killing the bacterial cell. Phage-encoded protein pIV, which is required for phage assembly and secretion, forms large highly conductive channels in the outer membrane of E. coli. It has been proposed that the phage are extruded across the bacterial outer membrane through pIV channels. To test this prediction, we developed an in vivo assay by using a mutant pIV that functions in phage export but whose channel opens in the absence of phage extrusion. In E. coli lacking its native maltooligosacharride transporter LamB, this pIV variant allowed oligosaccharide transport across the outer membrane. This entry of oligosaccharide was decreased by phage production and still further decreased by production of phage that cannot be released from the cell surface. Thus, exiting phage block the pIV-dependent entry of oligosaccharide, suggesting that phage occupy the lumen of pIV channels. This study provides the first evidence, to our knowledge, for viral exit through a large aqueous channel.

  10. The mechanism of astragaloside IV promoting sciatic nerve regeneration

    Institute of Scientific and Technical Information of China (English)

    Xiaohong Zhang; Jiajun Chen

    2013-01-01

    3-O-beta-D-xylopyranosyl-6-O-beta-D-glucopyranosyl-cycloastragenol (astragaloside IV), the main active component of the traditional Chinese medicine astragalus membranaceus, has been shown to be neuroprotective. This study investigated whether astragaloside IV could promote the repair of injured sciatic nerve. Denervated sciatic nerve of mice was subjected to anastomosis. The mice were intraperitoneal y injected with 10, 5, 2.5 mg/kg astragaloside IV per day for 8 consecutive days. Western blot assay and real-time PCR results demonstrated that growth-associated protein-43 ex-pression was upregulated in mouse spinal cord segments L 4–6 after intervention with 10, 5, 2.5 mg/kg astragaloside IV per day in a dose-dependent manner. Luxol fast blue staining and elec-trophysiological detection suggested that astragaloside IV elevated the number and diameter of myelinated nerve fibers, and simultaneously increased motor nerve conduction velocity and action potential amplitude in the sciatic nerve of mice. These results indicated that astragaloside IV con-tributed to sciatic nerve regeneration and functional recovery in mice. The mechanism underlying this effect may be associated with the upregulation of growth-associated protein-43 expression.

  11. Evolution of iv iron compounds over the last century.

    Science.gov (United States)

    Macdougall, Iain C

    2009-12-01

    Administration of intravenous (IV) iron has become pivotal in the management of anaemia in patients with chronic kidney disease (CKD). Since parenteral iron was first introduced for human use in the 1930s, things have come a long way. Seventy years ago, iron was toxic, administered as an iron oxyhydroxide complex. This problem was circumvented with the introduction of compounds containing iron in a core surrounded by a carbohydrate shell. The carbohydrate shell consists of molecules such as dextran, sucrose, dextrin or gluconate. The first dextran-containing IV iron preparations carried a small risk of anaphylaxis, but the more recently introduced low molecular weight iron dextran preparation has significantly less risk of this. Iron reactions occur with all IV iron preparations, but are generally not thought to be immune based. Recently, newer IV iron preparations have appeared in the market, including Ferumoxytol (Feraheme) and ferric carboxymaltose (Ferinject). These latest IV iron preparations do not contain a requirement for a test dose, and a much higher dose of iron can be delivered as a single administration. Thus, giving supplemental iron to man has come a long way since 1930s; we are now in an era when we are able to administer higher doses of iron with acceptable safety and without significant adverse effects. However, the long-term safety of the newer IV iron preparations is not yet established.

  12. Psicosomática y enfermedades visuales: la coriorretinopatía serosa central

    OpenAIRE

    Zavala, Patricia; Universidad Autónoma de Nuevo León; Álvarez, Javier; Universidad Autónoma de Nuevo León

    2014-01-01

    A través de un abordaje cualitativo, en el presente trabajo se estudian los elementos orgánicos de la enfermedad visual conocida como coriorretinopatía serosa central, así como las características psicológicas y sociales de algunos pacientes que la padecen. Asimismo, se discuten los aportes explicativos de la teoría psicoanalítica para el entendimiento de este tipo de enfermedades.

  13. Structure of the catalytic region of DNA ligase IV in complex with an Artemis fragment sheds light on double-strand break repair.

    Science.gov (United States)

    Ochi, Takashi; Gu, Xiaolong; Blundell, Tom L

    2013-04-02

    Nonhomologous end joining (NHEJ) is central to the repair of double-stranded DNA breaks throughout the cell cycle and plays roles in the development of the immune system. Although three-dimensional structures of most components of NHEJ have been defined, those of the catalytic region of DNA ligase IV (LigIV), a specialized DNA ligase known to work in NHEJ, and of Artemis have remained unresolved. Here, we report the crystal structure at 2.4 Å resolution of the catalytic region of LigIV (residues 1-609) in complex with an Artemis peptide. We describe interactions of the DNA-binding domain of LigIV with the continuous epitope of Artemis, which, together, form a three-helix bundle. A kink in the first helix of LigIV introduced by a conserved VPF motif gives rise to a hydrophobic pocket, which accommodates a conserved tryptophan from Artemis. We provide structural insights into features of LigIV among human DNA ligases.

  14. Valor nutritivo da forragem de genótipos de cereais de inverno de duplo propósito Nutritive value of forage of genotypes of double purpose winter cereals

    Directory of Open Access Journals (Sweden)

    Gilmar Roberto Meinerz

    2011-06-01

    Full Text Available Esta pesquisa foi conduzida com o objetivo de avaliar o valor nutritivo da forragem de 12 genótipos de seis espécies de cereais de inverno de duplo propósito (forragem e grãos, submetidos ao corte, na região da Depressão Central do Rio Grande do Sul. As espécies e genótipos testados foram: trigo (BRS 277, BRS Guatambu, BRS Tarumã, BRS Umbu; aveia-preta (Agro Zebu, UPFA 21 - Moreninha e Comum; aveia-branca (UPF 18; centeio (BR 1 e BRS Serrano; Cevada (BRS Marciana e triticale (BRS 148.Os genótipos foram distribuídos em 36 parcelas experimentais, num delineamento experimental inteiramente casualizado, com 12 tratamentos e três repetições. As análises de valor nutritivo e composição mineral foram feitas pelo método da reflectância do infravermelho proximal (NIRS, em amostras do estrato superior a 10 cm de altura da forragem. Os genótipos de aveia e o trigo BRS Umbu apresentaram os melhores resultados de valor nutritivo. A composição mineral apresentou pequena variabilidade entre os genótipos testados. Os resultados demonstram que os cereais de inverno produzem forragem de elevado valor nutritivo.The objective of this research was to evaluate the nutritive value of the forage of 12 genotypes of six double purpose (forage and grains winter cereal species submitted to harvest in the region of Depressão Central in Rio Grande do Sul state. The species and genotypes tested were: wheat (BRS 277, BRS Guatambu, BRS Tarumã and BRS Umbu; black oat (Agro Zebu, UPFA 21 - Moreninha and Commom black-oat; white-oat (UPF 18; rye (BR 1 and BRS Serrano; barley (BRS Marciana; and triticale (BRS 148. The genotypes were distributed in 36 experimental plots in completely randomized experimental design, with 12 treatments and three replications. Analysis of nutritive value and mineral composition were performed by the near infrared spectroscopy (NIRS in samples of stratum greater than 10 cm height of forage. Oat genotypes and BRS Umbu wheat

  15. 3D CENTRAL LINE EXTRACTION OF FOSSIL OYSTER SHELLS

    Directory of Open Access Journals (Sweden)

    A. Djuricic

    2016-06-01

    Full Text Available Photogrammetry provides a powerful tool to digitally document protected, inaccessible, and rare fossils. This saves manpower in relation to current documentation practice and makes the fragile specimens more available for paleontological analysis and public education. In this study, high resolution orthophoto (0.5 mm and digital surface models (1 mm are used to define fossil boundaries that are then used as an input to automatically extract fossil length information via central lines. In general, central lines are widely used in geosciences as they ease observation, monitoring and evaluation of object dimensions. Here, the 3D central lines are used in a novel paleontological context to study fossilized oyster shells with photogrammetric and LiDAR-obtained 3D point cloud data. 3D central lines of 1121 Crassostrea gryphoides oysters of various shapes and sizes were computed in the study. Central line calculation included: i Delaunay triangulation between the fossil shell boundary points and formation of the Voronoi diagram; ii extraction of Voronoi vertices and construction of a connected graph tree from them; iii reduction of the graph to the longest possible central line via Dijkstra’s algorithm; iv extension of longest central line to the shell boundary and smoothing by an adjustment of cubic spline curve; and v integration of the central line into the corresponding 3D point cloud. The resulting longest path estimate for the 3D central line is a size parameter that can be applied in oyster shell age determination both in paleontological and biological applications. Our investigation evaluates ability and performance of the central line method to measure shell sizes accurately by comparing automatically extracted central lines with manually collected reference data used in paleontological analysis. Our results show that the automatically obtained central line length overestimated the manually collected reference by 1.5% in the test set, which

  16. D Central Line Extraction of Fossil Oyster Shells

    Science.gov (United States)

    Djuricic, A.; Puttonen, E.; Harzhauser, M.; Mandic, O.; Székely, B.; Pfeifer, N.

    2016-06-01

    Photogrammetry provides a powerful tool to digitally document protected, inaccessible, and rare fossils. This saves manpower in relation to current documentation practice and makes the fragile specimens more available for paleontological analysis and public education. In this study, high resolution orthophoto (0.5 mm) and digital surface models (1 mm) are used to define fossil boundaries that are then used as an input to automatically extract fossil length information via central lines. In general, central lines are widely used in geosciences as they ease observation, monitoring and evaluation of object dimensions. Here, the 3D central lines are used in a novel paleontological context to study fossilized oyster shells with photogrammetric and LiDAR-obtained 3D point cloud data. 3D central lines of 1121 Crassostrea gryphoides oysters of various shapes and sizes were computed in the study. Central line calculation included: i) Delaunay triangulation between the fossil shell boundary points and formation of the Voronoi diagram; ii) extraction of Voronoi vertices and construction of a connected graph tree from them; iii) reduction of the graph to the longest possible central line via Dijkstra's algorithm; iv) extension of longest central line to the shell boundary and smoothing by an adjustment of cubic spline curve; and v) integration of the central line into the corresponding 3D point cloud. The resulting longest path estimate for the 3D central line is a size parameter that can be applied in oyster shell age determination both in paleontological and biological applications. Our investigation evaluates ability and performance of the central line method to measure shell sizes accurately by comparing automatically extracted central lines with manually collected reference data used in paleontological analysis. Our results show that the automatically obtained central line length overestimated the manually collected reference by 1.5% in the test set, which is deemed

  17. Los ejemplares tipo de Cicadellinae y Gyponinae (Hemiptera: Auchenorrhyncha: Cicadellidae depositados en el Museo de La Plata, Argentina

    Directory of Open Access Journals (Sweden)

    Susana L. PARADELL

    2010-01-01

    Full Text Available En la presente contribución, se realizó un relevamiento de los ejemplares tipo de Cicadellidae, depositados en la colección de la División Entomología del Museo de La Plata (MLP. Fueron examinados y listados 86 ejemplares tipo pertenecientes a 32 especies: siete Cicadellinae y 25 Gyponinae, las que fueron descriptas por los siguientes autores: Berg, DeLong, DeLong & Freytag, DeLong & Martinson, Spångberg , Tesón y Young. Para cada ejemplar tipo se brinda información acerca del nombre específico, referencia bibliográfica, categoría de tipo y procedencia.

  18. Banco Central de Costa Rica

    Directory of Open Access Journals (Sweden)

    Sauter, Franz

    1963-06-01

    Full Text Available This new building is intended to house the various services of the Central Bank of Costa Rica. It has a prestressed concrete structure, and consists of a basement parking space for 105 vehicles, and nine storeys, providing altogether a floor surface of 12,000 ms2. The building rests on a ground area of 40 by 60 ms, and the main structure occupies 22 by 45 ms. This Bank is located in a district of narrow streets, but its main side overlooks a green open space, which will improve its visibility and appearance. The building structure is made up of a framework of prestressed beams and columns. The beams have been concreted at the site, and the joists, which are also prestressed, are factory made. This framework, at each floor level, constitutes the basis of a continuous slab, which renders the total structure exceedingly stiff. The main continuous girders span 11.22 ms spaces, and vary in cross section. The prestressing reinforcements consist of 6 Loeba type cables. This is an original design by Dr. Leonhardt, in which the cables are placed on three horizontal layers, of parabolic outline. Each cable is made up of 12 x 5.4 mm wires, with a breaking stress of 180 kg/mm2 The tensioning stress was 108 kg/mm2, and the total prestress load is 29,700 kgs. The cables run in corrugated metal tubes, and these were kept in precise position with the aid of distance pieces.El nuevo edificio, destinado a agrupar los servicios del Banco Central de Costa Rica, está constituido por una estructura de hormigón pretensado. El inmueble dispone de un sótano, estacionamiento propio para 105 vehículos y nueve plantas, con una superficie total de 12.000 metros cuadrados. Se asienta sobre una base de 40x60 m, donde se levanta un núcleo central de 22x45 metros. Está situado en un barrio de calles estrechas, pero tiene su fachada, principal frente a una zona verde que le proporcionará mayor categoría y visibilidad. La estructura se compone de una retícula de vigas

  19. Central Pain Syndrome

    Science.gov (United States)

    ... or hands. Central pain syndrome often begins shortly after the causative injury or damage, but may be delayed by months or even years, especially if it is related to post-stroke pain. × Definition Central pain syndrome is a neurological ...

  20. Central centrifugal cicatricial alopecia

    Directory of Open Access Journals (Sweden)

    Collin Blattner

    2013-01-01

    Full Text Available Central centrifugal cicatricial alopecia is a common cause of progressive permanent apical alopecia. This unique form of alopecia includes entities previously know as "hot comb alopecia," "follicular degeneration syndrome," "pseudopelade" in African Americans and "central elliptical pseudopelade" in Caucasians. The etiology appears to be multifactorial and the condition occurs in all races.

  1. Optimal central bank transparency

    NARCIS (Netherlands)

    van der Cruijsen, C.A.B.; Eijffinger, S.C.W.; Hoogduin, L.

    2008-01-01

    Should central banks increase their degree of transparency any further? We show that there is likely to be an optimal intermediate degree of central bank transparency. Up to this optimum more transparency is desirable: it improves the quality of private sector inflation forecasts. But beyond the opt

  2. Optimal central bank transparency

    NARCIS (Netherlands)

    van der Cruijsen, C.A.B.; Eijffinger, S.C.W.; Hoogduin, L.H.

    2010-01-01

    Should central banks increase their degree of transparency any further? We show that there is likely to be an optimal intermediate degree of central bank transparency. Up to this optimum more transparency is desirable: it improves the quality of private sector inflation forecasts. But beyond the opt

  3. Factores asociados al auto-cuidado de la salud en pacientes diabéticos tipo 2

    OpenAIRE

    MB Amador-Díaz; FG Márquez-Celedonio; AS. Sabido-Sighler

    2007-01-01

    Objetivo: Cuantificar la prevalencia y los factores asociados al autocuidado de la salud en pacientes con diabetes tipo 2. Material y métodos. Mediante muestreo probabilistico fueron seleccionados 200 pacientes diabeticos tipo 2 a quienes se aplico una encuesta transversal analitica. Se aplico un cuestionario relacionado con el autocuidado de la salud; se investigo ademas el nivel de glucemia, factores sociodemograficos, culturales y psicologicos, analizados a traves de la razon de momios de ...

  4. Nuevas estrategias terapéuticas en diabetes mellitus tipo 1 New therapeutic strategies for type 1 diabetes mellitus

    OpenAIRE

    Barajas, M. (Miguel); Príncipe, R.M. (R.M.); Escalada, J.; Prósper, F; J. Salvador

    2008-01-01

    El principal determinante del riesgo de complicaciones derivadas de la diabetes mellitus tipo 1 se debe a los altos niveles de glucosa en sangre mantenidos durante largo tiempo. Para conseguir un beneficio terapéutico en pacientes con diabetes mellitus es necesario desarrollar tratamientos que permitan de manera segura, efectiva y estable mantener la normoglucemia. Lamentablemente, el tratamiento de la diabetes mellitus tipo 1 mediante el aporte exógeno de insulina no es capaz de conseguir ni...

  5. Resistência de biótipos de arroz-vermelho aos herbicidas imazapyr + imazapic e alternativas de controle

    Directory of Open Access Journals (Sweden)

    Rafael Salles Rubin

    2014-10-01

    Full Text Available O uso intenso de herbicidas com o mesmo mecanismo de ação na cultura do arroz (Oryza sativa L. tem selecionado biótipos resistentes, como, por exemplo, o arroz-vermelho (planta daninha resistente aos herbicidas imidazolinonas. Por essa razão, este trabalho foi desenvolvido com o objetivo de avaliar a resistência de arroz-vermelho ao herbicida imazapyr + imazapic, na região sul do Rio Grande do Sul, e o controle do biótipo resistente de arroz-vermelho com os herbicidas alternativos clethodim e glyphosate. Foram realizados três experimentos, em delineamento casualizado, arranjados em esquema fatorial. No primeiro experimento, o fator A testou biótipos de arroz-vermelho [ORYSA 184 (resistente e ORYSA 188 (susceptível], o fator B comparou herbicidas (imazapyr + imazapic, clethodim e glyphosate e o fator C avaliou doses dos herbicidas (0; 0,5; 1; 2; 4; 8; 16 e 32 vezes a dose recomendada. No segundo, compararam-se biótipos de arroz-vermelho e doses do herbicida imazapyr + imazapic (0; 0,5; 1; 2; 4; 8; 16; 32 e 64 vezes a dose recomendada. No terceiro, testaram-se biótipos de arroz-vermelho e doses diferentes do herbicida imazapyr + imazapic para cada biótipo. O biótipo ORYSA 184 é resistente ao imazapyr + imazapic, quando aplicada a dose máxima de registro e estádio indicado. Os herbicidas clethodim e glyphosate, detentores de mecanismos de ação alternativos, controlam o biótipo resistente ORYSA 184 de arroz-vermelho.

  6. Adaptabilidade, estabilidade e resistência a patógenos em genótipos de feijoeiro

    Directory of Open Access Journals (Sweden)

    Cleber Vinicius Giaretta Azevedo

    2015-10-01

    Full Text Available Resumo:O objetivo deste trabalho foi avaliar a resistência de genótipos de feijoeiro aos principais patógenos da cultura, bem como a adaptabilidade e a estabilidade de produção de grãos desses genótipos. Avaliaram-se 26 genótipos de feijoeiro quanto à resistência a Colletotrichum lindemuthianum, Fusarium oxysporum f. sp. phaseolie Xanthomonas axonopodis pv. phaseoli, por meio de inoculação, em laboratório, e em 19 ensaios de valor de cultivo e uso (VCU, em diferentes locais do Estado de São Paulo, nas safras das "águas", "seca" e "inverno", durante os anos agrícolas 2011, 2012 e 2013. Dezoito genótipos foram considerados resistentes: sete deles a C. lindemuthianum, sete a F. oxysporumf. sp. phaseolie quatro a X. axonopodispv. phaseoli. A reação de resistência aos patógenos está associada à estabilidade dos genótipos. Por meio das análises GGE biplot, foi possível identificar genótipos com adaptabilidade e estabilidade superiores às das testemunhas, nos dois grupos de tegumento avaliados, em todas as épocas de semeadura.

  7. Tris(cyclohexylammonium cis-dichloridobis(oxalato-κ2O1,O2stannate(IV chloride monohydrate

    Directory of Open Access Journals (Sweden)

    Modou Sarr

    2013-11-01

    Full Text Available The crystal structure of the title compound, (C6H14N3[Sn(C2O42Cl2]Cl·H2O, contains three cyclohexylammonium cations, one stannate(IV dianion, one isolated chloride anion and one lattice water molecule. The cyclohexylammonium cations adopt chair conformations. In the complex anion, two bidentate oxalate ligands and two chloride anions in cis positions coordinate octahedrally to the central SnIV atom. The cohesion of the molecular entities is ensured by the formation of N—H...O, O—H...O, O—H...Cl and N—H...Cl interactions involving cations, anions and the lattice water molecule, giving rise to a layer-like arrangement parallel to (010.

  8. Characterization of human and mouse peroxiredoxin IV: Evidence for inhibition by Prx-IV of epidermal growth factor- and p53-induced reactive oxygen species

    OpenAIRE

    Wong, CM; Kok, KH; Jin, DY; Chun, ACS; Zhou, Y.; Fung, PCW; Kung, HF; Jeang, KT

    2000-01-01

    The aim of this study was to identify and characterize human and mouse Prx-IV. We identified mouse peroxiredoxin IV (Prx-IV) by virtue of sequence homology to its human ortholog previously called AOE372. Mouse Prx-IV conserves an amino-terminal presequence coding for signal peptide. The amino acid sequences of mature mouse and human Prx-IV share 97.5% identity. Phylogenetic analysis demonstrates that Prx-IV is more closely related to Prx-I/-II/-III than to Prx-V/-VI. Previously, we mapped the...

  9. SDSS IV MaNGA - The spatially resolved transition from star formation to quiescence

    CERN Document Server

    Belfiore, Francesco; Maraston, Claudia; Emsellem, Eric; Bershady, Matthew A; Masters, Karen L; Bizyaev, Dmitry; Boquien, Médéric; Brownstein, Joel R; Bundy, Kevin; Diamond-Stanic, Aleksandar M; Drory, Niv; Heckman, Timothy M; Law, David R; Malanushenko, Olena; Oravetz, Audrey; Pan, Kaike; Roman-Lopes, Alexandre; Thomas, Daniel; Weijmans, Anne-Marie; Westfall, Kyle B; Yan, Renbin

    2016-01-01

    Using spatially resolved spectroscopy from SDSS-IV MaNGA we have demonstrated that low ionisation emission line regions (LIERs) in local galaxies result from photoionisation by hot evolved stars, not active galactic nuclei. LIERs are ubiquitous in both quiescent galaxies and in the central regions of galaxies where star formation takes place at larger radii. We refer to these two classes of galaxies as extended LIER (eLIER) and central LIER (cLIER) galaxies respectively. cLIERs are late type galaxies located around the green valley, in the transition region between the star formation main sequence and quiescent galaxies. These galaxies display regular disc rotation in both stars and gas, although featuring a higher central stellar velocity dispersion than star forming galaxies of the same mass. cLIERs are consistent with being slowly quenched inside-out; the transformation is associated with massive bulges, pointing towards the importance of bulge growth via secular evolution. eLIERs are morphologically early...

  10. Variación de la actividad cognitiva en diferentes tipos de pruebas de fluidez verbal.

    Directory of Open Access Journals (Sweden)

    Julián C. Marino

    2009-12-01

    Full Text Available En esta investigación se aplicaron diez pruebas de fluidez verbal del tipo fonológico, categorial, gramatical y combinadas a 259 adultos argentinos (15 a 70 años con el fin de conocer su correlación con la actividad ejecutiva, semántica y atencional. Se indagó sobre la estructura teórica de cada prueba de fluidez verbal, a fines de determinar la lógica de sus variaciones. El objetivo final de la investigación fue aportar al desarrollo de un explorador neuropsicológico en fluidez verbal, que sea útil para hacer evaluaciones breves y sencillas, incluyendo situaciones difíciles como pacientes hospitalizados, y tratando de extraer la máxima información posible de la actividad cognitiva. RESULTADOS: se realizaron análisis descriptivos sobre las pruebas de fluidez verbal, análisis factorial sobre las variables de la actividad cognitiva y análisis de regresión múltiples, ingresando como variables independientes las variables cognitivas y como dependientes cada una de las pruebas de fluidez verbal. CONCLUSIONES: los modelos predictivos hallados indican variaciones sistemáticas en relación al compromiso cognitivo entre los tipos de pruebas de fluidez verbal. También se hallaron variaciones dentro de cada tipo. Esto indica que el explorador en fluidez verbal puede ser una herramienta útil para evaluar diferentes capacidades y funciones cognitivas.

  11. Qualidade do leite cru tipo C e refrigerado em sistemas leiteiros tradicionais do sudoeste goiano

    Directory of Open Access Journals (Sweden)

    Aurélio Ferreira Melo

    2013-12-01

    Full Text Available Objetivou-se avaliar a qualidade do leite cru tipo C e cru refrigerado de sistemas leiteiros pouco tecnificados do Sudoeste Goiano, e verificar se o leite produzido atende às exigências previstas na instrução normativa 62/2011. Coletou-se 49 amostras de leite cru tipo C e leite cru refrigerado, em condições assépticas, utilizando frascos de 40 mL, contendo conservante Azidiol® para análise da CBT e Bronopol® para determinação da CCS e composição química. As análises eletrônicas foram realizadas no Laboratório de Qualidade do Leite do Centro de Pesquisa em Alimentos da Escola de Veterinária e Zootecnia da Universidade Federal de Goiás. Para comparação das médias entre os tratamentos utilizou-se o teste de Tukey a 5% de probabilidade. Os resultados de gordura e CCS evidenciaram que a maior ocorrência de mastite no leite proveniente de refrigeração tem relação direta com o aumento do teor de gordura do leite. A contagem bacteriana total do leite tipo C e refrigerado foram mais elevadas que o limite estabelecido pela legislação brasileira de qualidade do leite, e indicou a necessidade de maior atenção à higiene durante a obtenção e estocagem do leite.

  12. Pipe type poles in transmission power lines; Postes tipo tubo en lineas de transmision

    Energy Technology Data Exchange (ETDEWEB)

    Cervantes E, Mario; Becerril A, Armando [Luz y Fuerza del Centro, Mexico, D. F. (Mexico)

    1997-12-31

    The first supports for transmission power lines were relatively small structures, of simple configuration, to save reduced clearances to resist load in accordance with its need; with the technical development, gradually appeared higher and higher electric tensions and greater obstacles to overcome, consequently the design of the supports had to be adapted to the new conditions. This gave rise to the development of a specific technique that would adequate and incorporate the continuous engineering advances. In this document the initial considerations on the design poles pipe type are examined; within these considerations mention is made of: the design, the manufacture, the prototype tests, installation, quality control and foundations. The type tube pole is portrayed, as well as the steel reinforcement, finally the types of precast foundations are shown [Espanol] Los primeros soportes para lineas de transmision fueron estructuras relativamente pequenas, de configuracion simple, para salvar claros reducidos y resistir cargas proporcionales a sus necesidades, con el desarrollo de la tecnica, fueron apareciendo tensiones electricas cada vez mas elevadas y obstaculos mayores que vencer, por lo que el diseno de los soportes tuvo que adaptarse a las nuevas condiciones. Esto dio origen al desenvolvimiento de una tecnica especifica que fuese adecuando e incorporando los continuos avances de la ingenieria. En este documento se tratan las consideraciones iniciales del diseno de los postes tipo tubo; dentro de estas consideraciones se citan: el diseno, la fabricacion, las pruebas de prototipo, montajes, control de calidad y cimentaciones. Se ilustra el poste tipo tubo, al igual que el armado del poste, por ultimo se muestra los tipos de cimentaciones precoladas

  13. CONTROL PREDICTIVO DE UN ROBOT TIPO SCARA PREDICTIVE CONTROL OF A SCARA ROBOT

    Directory of Open Access Journals (Sweden)

    Oscar Andrés Vivas Albán

    2006-08-01

    Full Text Available Este artículo presenta una aplicación eficiente de un control por modelo de referencia sobre un robot de tipo SCARA. El control estudiado es un control predictivo funcional, el que hace uso de un modelo dinámico simplificado del robot. Los ensayos simulados se realizan sobre un robot de cuatro grados de libertad, tipo SCARA. Con el fin de comparar diferentes estrategias de control, se diseña un controlador clásico tipo PID y dos controladores basados en el modelo de referencia. En este último caso el sistema se linealiza y se desacoplada por realimentación, lo que transforma el sistema a controlar en un simple par de integradores. Al sistema lineal y desacoplado resultante se le aplica el control por par calculado y el control predictivo funcional. Los tres controladores estudiados se simulan sobre el robot SCARA con valores numéricos reales. Las pruebas permiten valorar las respuestas de estos controladores en seguimiento de trayectoria, rechazo de perturbaciones y presencia de errores en el modelado con consignas complejas similares a las utilizadas en procesos de fabricación.This paper describes an efficient approach for model based control, applied on a SCARA robot. The studied control is the predictive functional control which uses a simplified dynamical model of the robot. The simulated tests are made on a SCARA type robot, with four DOF. To compare several control strategies, a classical PID control and two model based controllers are designed. In the last case, the model is first linearized and decoupled by feedback, transforming the system into a double set of integrators. Computed torque control and predictive functional control are applied to the linear and decoupled system. The three studied controllers are simulated on the SCARA robot with real numerical values. Tracking performance, disturbance rejection and model robot mismatch are enlightened, using complex machining tasks trajectories and error presence in the modelling

  14. El coste de la diabetes tipo 2 en España: El estudio CODE-2

    Directory of Open Access Journals (Sweden)

    Mata M.

    2002-01-01

    Full Text Available Objetivo: Estimar el coste de la atención sanitaria al paciente diabético tipo 2, diferenciando el gasto derivado del control de la enfermedad, de la atención de sus complicaciones y de otros costes directos asociados. Métodos: Recogida retrospectiva del consumo de recursos a partir de la historia clínica y la entrevista personal en 29 centros de atención primaria de todo el territorio nacional de una muestra de pacientes seleccionados de forma aleatoria a partir del registro de diabéticos de cada centro. Resultados: Se evaluó a 1.004 pacientes (561 mujeres con una media de edad de 67,42 años y una media de evolución de la enfermedad de 10,07 años. El 50,9% no presentaba complicaciones, el 17,7% sólo macrovasculares, el 19,5% sólo microvasculares y el 11,9% ambas. El coste anual sanitario por paciente fue de 1.305,15 euros. De este coste el 28,6% (373,27 euros estaba relacionado directamente con el control de la diabetes, el 30,51% (398,20 euros con sus complicaciones y el 40,89% (533,68 euros no estaba relacionado. El coste medio de un paciente sin complicaciones fue de 883 euros frente a 1.403 de un paciente con complicaciones microvasculares, 2.022 cuando existían complicaciones macrovasculares y 2.133 cuando coexistían ambos tipos de complicaciones. Conclusiones: El elevado coste del tratamiento de la diabetes tipo 2 y sus complicaciones, sugiere la posibilidad de que la mejora del control de la enfermedad pueda no sólo mejorar la supervivencia y la calidad de vida, sino reducir los costes asociados con las complicaciones crónicas.

  15. Tipo de cambio, exportaciones e importaciones: El caso de la economía boliviana

    OpenAIRE

    2000-01-01

    Recientemente, como resultado de las salidas de capitales de las economías emergentes, ha vuelto la preocupación por los elevados déficit comerciales y el retorno a políticas cambiarias más activas. En el caso de Bolivia, debido a los saldos comerciales deficitarios que le caracterizan, surge la preocupación por el papel de la política cambiaria para tratar dichos déficit y la interrogante es ¿cuán elásticas son las exportaciones y las importaciones a las variaciones en el tipo de cambio real...

  16. Indicadores de neuropatia autonômica cardiovascular em pacientes com diabetes tipo 1

    OpenAIRE

    Lucianne Righeti Monteiro Tannus

    2014-01-01

    A Neuropatia autonômica cardiovascular (NAC), apesar de ter sido apontada como fator de risco independente para doença cardiovascular (DCV) em pacientes com diabetes tipo 1 (DM1), permanece subdiagnosticada. Os objetivos do trababalho foram determinar a prevalência de NAC e seus indicadores clínicos e laboratoriais em pacientes com DM1 e a associação com outras complicações crônicas do diabetes, além de avaliar a concordância entre os critérios diagnósticos da NAC determinados pelos parâmetro...

  17. Patrón de conducta tipo A y pautas educativas

    OpenAIRE

    Castro Fornieles, Josefina

    1993-01-01

    [spa] A finales de la década de los años cincuenta, dos cardiólogos, M. Friedman y R.H. Rosenman (1959), identificaron una serie de actitudes y comportamientos en sus pacientes coronarios que consideraron favorecían la aparición de problemas coronarios. Al conjunto de estas características le dieron el nombre de patrón de conducta tipo A (PCTA). Sus elementos principales son: estilo duro y competitivo, impaciencia y ritmo acelerado y además una excesiva implicación laboral con actividad inces...

  18. ¿Conviene flexibilizar el tipo de cambio para mejorar la competitividad?

    OpenAIRE

    Guadalupe Mántey

    2013-01-01

    En este artículo se investigan los efectos de una devaluación cambiaria en la dinámica exportadora de los países en desarrollo. En oposición a la teoría convencional, se muestra que el efecto negativo de esa medida en las hojas de balance de las empresas exportadoras, por su elevada dolarización de pasivos, anula la posible ganancia en competitividad. Con base en los resultados de la investigación empírica, se argumenta que el establecimiento de un tipo de cambio real competitivo y estable, p...

  19. Resposta de biótipos de Euphorbia heterophylla a doses de glyphosate.

    OpenAIRE

    Vargas, L.; M.A. Nohatto; D. Agostinetto; M.A. Bianchi; Gonçalves, E. M.; R.E. Toledo

    2012-01-01

    A leiteira (Euphorbia heterophylla) é uma planta daninha de ciclo anual encontrada com frequência em lavouras de soja na região Sul do Brasil, controlada em lavouras de soja geneticamente modificada (Roundup Ready® - RR) com uso do herbicida glyphosate. Entretanto, nos últimos anos, o controle dessa espécie não tem sido satisfatório em alguns locais, provocando a suspeita de que foram selecionados biótipos resistentes ao herbicida. Diante disso, o objetivo deste trabalho foi avaliar, por meio...

  20. Tipos de personalidad del mexicano: Desarrollo y validación de una escala

    OpenAIRE

    Cruz Martínez,Luz María; Rivera Aragón,Sofía; Díaz Loving,Rolando; Taracena Ruíz,Bertha Elvia

    2013-01-01

    La investigación ha tratado de identificar la existencia de rasgos universales personalidad, la investigación etnopsicológica ha buscado identificar las cualidades típicas de personalidad de los miembros de diferentes grupos socio culturales; aunque sin acordar cuáles son, ni su relación con los modelos generales como el de los Cinco Grandes. Esta investigación consistió en identificar y describir los tipos de personalidad del mexicano propuestos por Díaz Guerrero (1997). Se realizaron dos es...

  1. Perfil Neuropsicológico de la Enfermedad de Niemann Pick Tipo C: Estudio de Caso

    OpenAIRE

    Molina, David Andres; Gómez, Mónica

    2016-01-01

    El síndrome de Niemann-Pick es una enfermedad caracterizada por falla en el metabolismo lipídico y su almacenamiento a nivel lisosomal, cuya causa esta relacionada con mutaciones específicas en los genes NPC1 y NPC2, los cuales producen acumulación de colesterol no esterificado y esfingolípidos en los lisosomas. El presente artículo expone un perfil  neuropsicológico de la Enfermedad de Niemann Pick Tipo C, padecida por un paciente  masculino de nueve años edad. Se realizo un estudio de caso ...

  2. ESTUDO BIOMÉTRICO DE RATOS ALIMENTADOS COM DOIS TIPOS DE DIETA

    OpenAIRE

    Alice Cristina Antonio dos Santos; Ana Carolina Tocilo Lopes; Gláucia de Cássia Xavier da Cruz; Bruna Corral Garcia; Fábio Yoshikazu Kodama; Regina Celi Trindade Camargo; José Carlos Silva Camargo Filho

    2010-01-01

    A dieta hipercalórica é tida como fator de risco para o desenvolvimento de doenças cardiovasculares, sendo preocupante para a saúde pública mundial. O objetivo do presente estudo foi comparar a biometria de ratos alimentados por dois tipos de dieta. Para tanto, foram utilizados 24 ratos Wistar machos com 90 dias com oferta de ração e água à vontade; divididos em G1 recebendo dieta normocalórica e G2, dieta hipercalórica. A ingesta alimentar foi mensurada diariamente. Após 18 semanas foram eut...

  3. Propuesta de un algoritmo de control en lazo cerrado para la diabetes tipo 1

    OpenAIRE

    2010-01-01

    La diabetes mellitus es un trastorno del metabolismo de los carbohidratos producido por la insuficiente o nula producción de insulina o la reducida sensibilidad a esta hormona. Es una enfermedad crónica con una mayor prevalencia en los países desarrollados debido principalmente a la obesidad y la vida sedentaria. La diabetes Tipo 1 es una enfermedad autoinmune en la que son destruidas las células beta del páncreas, que producen la insulina, y por tanto es necesaria la administración de insuli...

  4. Alteraciones electrocardiográficas y factores de riesgo cardiovascular en pacientes con diabetes tipo 2

    Directory of Open Access Journals (Sweden)

    Rodríguez-Morán Martha

    1999-01-01

    Full Text Available Objetivo. Determinar cuáles son las alteraciones del ritmo y la conducción cardiaca más frecuentes en pacientes con diabetes tipo 2 sin cardiopatía previa y establecer su asociación con los factores de riesgo cardiovascular. Material y métodos. Se incluyeron pacientes con diabetes tipo 2 sin presencia o antecedentes de cardiopatía. Se determinaron los factores de riesgo cardiovascular, el índice de masa corporal y los niveles séricos de glucosa, colesterol y triglicéridos. Se registró electrocardiograma convencional en reposo. La asociación de las variables en estudio con la ocurrencia de arritmias se calculó con un modelo de análisis multivariado ajustado por sexo. Resultados. Se integraron 199 pacientes: 113 mujeres (56.8% y 86 hombres (43.2%, y se identificó algún tipo de alteración electrocardiográfica en 29.1% de los sujetos. El hemibloqueo fascicular anterior (HFA y el bloqueo completo de rama derecha del Haz de His (BRDHH, constituyeron 75.9% de las alteraciones identificadas. Los pacientes con trastornos del ritmo y la conducción tienen niveles más elevados de colesterol y triglicéridos. La aparición de arritmias se relaciona directamente con el incremento de la edad (r= 0.75, p= 0.01. En el análisis multivariado ajustado por sexo la hipercolesterolemia y la edad se asociaron significativamente con las alteraciones del ritmo y la conducción: RM 1.5, IC95% 1.1-4.6, p< 0.05 y RM 1.3, IC95% 1.0-5.2, p< 0.05, respectivamente. Conclusiones. Las alteraciones del ritmo y la conducción cardiaca más frecuentes en la diabetes tipo 2 son el HFA y el BRDHH; la hipercolesterolemia y la edad son los factores asociados a su presencia.

  5. Relaciones hídricas y temperaturas altas en frijol del tipo "flor de mayo"

    OpenAIRE

    2010-01-01

    Se estudió el efecto del déficit hídrico del suelo y temperatura alta del aire en las relaciones hídricas y temperatura del dosel del cultivo (Tc), rendimiento de semilla (RS) y sus componentes en 8 variedades de frijol del tipo ?Flor de Mayo? (FM) y una variedad criolla. Se realizaron 3 experimentos de campo; Montecillo en riego (MR) con la aplicación de agua de la siembra a la madurez, Montecillo en secano (MS) con la lluvia como fuente única de humedad y Celaya en secano (CS) con lluvia y ...

  6. Simulación estocástica de esquemas piramidales tipo Ponzi

    OpenAIRE

    Lilia Quituisaca-Samaniego; Juan Mayorga - Zambrano; Paúl Medina

    2013-01-01

    Mediante simulación, se estudian varios casos de fraude provocados por pirámides financieras tipo Ponzi (incluyendo los casos Madoff, DRFE y Cabrera); la técnica empleada corresponde a la implementación computacional de un modelo estocástico diseñado por J. Mayorga-Zambrano. Se comparan datos reales con aquellos generados por el software implementado; en particular, se estudia la evolución del número de clientes, del monto de estafa y del tiempo estimado de duración de la pirámide.

  7. Autopercepción de calidad de vida en adultos mayores con diabetes mellitus tipo 2

    OpenAIRE

    Noé Alfaro-Alfaro; María del Rayo Carothers Enriquez; Yesica Sughey González Torres

    2006-01-01

    La Diabetes Mellitus tipo 2 (DM2), es una enfermedad crónico- degenerativa de alta prevalencia, es la primera causa de consulta de especialidades, la segunda en medicina familiar y la causa más importante de pensión por invalidez en el Instituto Mexicano del Seguro Social. Los enfermos presentan complicaciones macro y microvasculares, cuando no existe buen control, afecta tanto su funcionalidad física, psicológica, social y calidad de vida (CV). El objetivo de este artículo fue determinar la ...

  8. Autocuidado en el adulto mayor con diabetes tipo 2. Monterrey, México.

    OpenAIRE

    Flores-Pérez, Martha Nelly; Garza-Elizondo,María Eugenia; Hernández-Cortés, Perla Lizeth

    2016-01-01

    Objetivos: determinar diferencias de autocuidado por edad ysexo en adultos mayores con diabetes tipo 2, que acuden a la consulta de medicina familiar. Material y métodos: estudio descriptivo de corte trasversal. La muestra estuvo constituida por 109 adultos mayores (63 Mujeres y 46 Hombres). Se aplicó el Resumen de Actividades de Autocuidado en Diabetes, se utilizó estadística descriptiva (frecuencias simples y relativas, medidas de dispersión e IC95%), U de Mann-Whitney y diferencia de propo...

  9. Perfil inmunohistoquímico de los adenocarcinomas nasosinusales de tipo intestinal y lesiones premalignas

    OpenAIRE

    Vivanco Allende, Blanca

    2016-01-01

    INTRODUCCIÓN: Los adenocarcinomas nasosinusales tipo intestinal (ITAC) son tumores primarios malignos de la cavidad nasal y los senos paranasales fuertemente relacionados con la exposición al polvo de madera. Se presentan con una clínica anodina, se diagnostican en estadios tardíos y muestran una supervivencia del 50% a los 5 años. Se han realizado varios estudios de expresión inmunohistoquímica (IHQ) con limitado número de casos. Aún no se ha demostrado la existencia de claras lesiones precu...

  10. Diabetes tipo 2: nivel socioeconómico y adhesión al tratamiento

    OpenAIRE

    Sáez, María Eugenia

    2011-01-01

    En el mundo hay más de 220 millones de personas con diabetes y el estilo de vida actual, el sedentarismo y el aumento de peso contribuyen a que este número siga en aumento. Alimentarse saludablemente y hacer actividad física, previene el avance de la diabetes tipo 2 y al ser ésta una enfermedad crónica, el tratamiento debe adaptarse a la vida del paciente para que éste pueda cumplirlo y de ésta manera prevenir las complicaciones propias de la enfermedad. En la presente inves...

  11. Cariótipo Fetal em Líquido Pleural Obtido por Toracocentese

    OpenAIRE

    Cabral Antonio Carlos Vieira; Machado Isabela Nelly; Leite Henrique Vitor; Pereira Alamanda Kfoury; Vitral Zilma Nogueira Reis

    2001-01-01

    Objetivos: avaliar a efetividade da realização de cariótipo em líquido pleural obtido por toracocentese de um grupo de fetos portadores de derrame pleural. Métodos: foram avaliados 15 fetos com derrame pleural uni ou bilateral nos quais se realizou uma punção da cavidade torácica. A idade gestacional variou entre 19 e 34 semanas. Os fetos foram estudados com ultra-sonografia morfológica para determinar a presença de anomalias associadas. Nos casos em que não se obteve o cultivo em líquido ple...

  12. Sobre la finitud de las series de potencias infinitas de tipo geométrico-polinomiales

    OpenAIRE

    Braddock Stradtmann, George

    2015-01-01

    Una investigación que inicié a mediados del año 2004, para tratar de encontrar cómo pudieron hacer los matemáticos de fines del siglo XVII, para encontrar la suma de algunas series de potencias infinitas, como por ejemplo la serie , la pude concluir exitosamente.A ese tipo de series yo las llamo geométrico-polinomiales, ya que son series geométricas, con coeficientes dados por una función polinomial , de grado Usando técnicas similares a las que usaban los matemáticos de aquellos tiempos, enc...

  13. RADIOEMISSÕES SOLARES TIPO II ASSOCIADAS A FLARES E CMES

    Directory of Open Access Journals (Sweden)

    Rafael Douglas Cunha-Silva

    2013-12-01

    Full Text Available Atribuídas a ondas de choque e a ejeções de plasmoide, as emissões solares tipo II são ondaseletromagnéticas geradas a partir de oscilações do plasma coronal. A origem dos choques associados a essasemissões é ainda uma questão em aberto da física solar. Enquanto alguns trabalhos sugerem os flares solarescomo seus acionadores, outros fornecem indícios de serem as ejeções de massa coronal (CMEs sua origemmais provável. Este trabalho apresenta os resultados da análise de duas emissões tipo II, registradas por doisespectrômetros da rede e-CALLISTO (extended-Compound Astronomical Low-cost Low-frequency Instrument forSpectroscopy and Transportable Observatory, os quais operam na faixa de frequências de 45-870 MHz. Oprimeiro evento, observado em 13 de junho de 2010, às 05:38 UT, apresentou uma taxa de deriva em frequênciade -0,2 MHz s-1, correspondente a uma velocidade de choque de 528 km s-1, estando, temporalmente, associadoa uma CME lenta (~320 km s-1 e a um flare solar em raios-X, classe M1.0. O segundo evento, observado em 09de Agosto de 2011, às 08:02 UT, apresentou uma taxa de deriva em frequência de -1,4 MHz s-1, correspondentea uma velocidade de choque de 1375 km s-1, estando, temporalmente, associado a uma CME tipo halo (~1610km s-1 e a um flare solar em raios-X, classe X6.9. Os resultados obtidos, para os parâmetros observacionais dasemissões tipo II e para os parâmetros físicos de suas fontes, são discutidos no contexto de sua relação com seuflares e CMEs associados.

  14. Atividade física na criança com diabetes tipo 1

    Directory of Open Access Journals (Sweden)

    Cristiane P. Miculis

    2010-08-01

    Full Text Available OBJETIVO: Abordar os aspectos práticos da realização segura de atividade física e esportes em crianças e adolescentes portadores de diabetes tipo 1. FONTES DOS DADOS: A pesquisa dos artigos foi conduzida em fontes de dados nacionais (SciELO e internacionais (PubMed/MEDLINE, assim como nas próprias referências dos artigos encontrados, adotando como limites: artigos publicados nos últimos 10 anos, preferencialmente conduzidos em crianças e adolescentes com diabetes tipo 1, sendo em sua maioria estudos experimentais e meta-análises sobre atividade física. SÍNTESE DOS DADOS: Com o metabolismo aeróbico, os músculos esqueléticos consomem maior quantidade de glicose para gerar energia, o que diminui a gliconeogênese hepática, levando a uma diminuição na glicemia e aumentando o risco de hipoglicemia. A reposição de carboidratos antes, durante e após o exercício em quantidade adequada e a redução da dose de insulina de ação rápida (pré-refeição são os principais aliados da criança e adolescente com diabetes tipo 1 para evitar a ocorrência da hipoglicemia severa. CONCLUSÕES: Para a reposição de carboidratos e a redução da dose de insulina, deve-se considerar o tipo, a duração e a intensidade da atividade física, bem como o horário de sua realização. A participação em diversos esportes, coletivos e individuais, e em atividades físicas de intensidades variadas é possível, sendo muito recomendado no tratamento do diabetes infantil.

  15. Isolamento do vírus Parainfluenza bovino tipo 3 no Rio Grande do Sul, Brasil

    Directory of Open Access Journals (Sweden)

    Gonçalves Diocela Andrade

    2003-01-01

    Full Text Available É descrito o isolamento do vírus Parainfluenza bovino tipo 3 (bPI-3 a partir de secreções nasais coletadas de um bovino com infecção respiratória. A identificação do agente foi realizada através de isolamento em cultivo celular e confirmada por testes de hemaglutinação, inibição da hemaglutinação, hemadsorção e imunofluorescência direta. Este é o primeiro registro do isolamento do vírus no Rio Grande do Sul.

  16. Aislamiento del virus herpes bovino tipo 1 en bovinos del departamento de Córdoba - Colombia

    OpenAIRE

    Victor Vera A; César Betancur H.

    2008-01-01

    Objetivo. Realizar el aislamiento del virus herpes bovino tipo 1 (BHV-1) en ganado bovino con antecedentes de infertilidad. Materiales y métodos. A partir de 85 animales, provenientes de diferentes áreas rurales del departamento de Córdoba, Colombia, sin antecedentes de vacunación y con titulos neutralizantes contra la enfermedad de la rinotraqueitis bovina infecciosa (IBR) por seroneutralización, se escogieron dos toros y una vaca para hacer aislamiento de HVB-1. Los animales fueron inmun...

  17. Glicooligómeros con uniones de tipo pseudoamida y estudio de sus interacciones con fosfato

    OpenAIRE

    Bootello Iglesias, Purificación

    2007-01-01

    Esta Tesis describe el diseño, síntesis y determinación de las propiedades de reconocimiento molecular de una nueva familia de mimeticos oligosacarídicos que incorporan puentes intersacarídicos de tipo pseudoamida: urea, tiourea y guanidina. En la memoria se describen metodologías sintéticas para la preparación de monómeros multifuncio nalizados a partir de los cuales se construyeron glicooligómeros de estructura diversa: lineales, ramificadas y dendríticas. Se han puesto a punto estrategias ...

  18. T1 Tejidos Residenciales Densos y Complejos (formas, tipos edificatorios, agrupaciones)

    OpenAIRE

    López de Lucio, Ramón; Ruiz, Javier

    2014-01-01

    Taller 1: Tejidos Residenciales Densos y Complejos. Formas, tipos edificatorios, agrupaciones. Esquema teórico simplificado de un sector urbano de 2,5 km2 potencialmente sostenible:Población total comprendida entre 37 y 53 mil habitantes manejando densidades brutas medias ó medias—altas: 45—65 viviendas por hectárea.Equipamientos educativos, deportivos, sanitarios y comerciales cotidianos, jardines de barrio y transporte público a menos de 10 minutos andando desde todas las viviendas (500m).I...

  19. Diabetes Mellitus tipo 1: controle glicêmico e fatores de risco cardiovasculares em adultos

    OpenAIRE

    GONÇALVES, Alessandra Rocha

    2012-01-01

    Objetivo: Avaliar o estado nutricional, o controle glicêmico e a prevalência dos fatores de risco cardiovasculares em pacientes adultos com diabetes mellitus tipo 1 (DM1), atendidos no ambulatório de nutrição e endocrinologia do Hospital Geral de Goiânia (HGG). Metodologia: Estudo transversal, realizado entre março e agosto/2011, cujos critérios de inclusão foram: diagnóstico consolidado da doença há pelo menos seis meses, idade maior ou igual a dezenove anos e menor que ses...

  20. Dispositivo de lectura de microarrays de tipo eléctrico y reutilizable

    OpenAIRE

    Fernández Sánchez, César; Bonilla Aguilar, Diana Lissette; Baldi Coll, Antonio; Rica Quesada, Roberto de la

    2010-01-01

    Dispositivo de lectura de microarrays de tipo eléctrico y reutilizable. El objeto principal de la presente invención es un dispositivo de lectura eléctrica de microarrays que se puede limpiar y volver a utilizar más de una vez. El dispositivo (1, 1’, 1”) de lectura de microarrays (6) tiene las siguientes partes: una base (2, 2’, 2”), que tiene unos medios de apoyo (3, 3’, 3”) para situar la superficie de test (7) del microarray (6) en paralelo a una superficie de lectu...

  1. Efectos de la entrevista motivacional en el tratamiento de la diabetes mellitus tipo 2

    OpenAIRE

    García Flores, Raquel; Universidad Nacional Autónoma de México; Sánchez Sosa, Juan José; Universidad Nacional Autónoma de México

    2013-01-01

    El objetivo del presente estudio fue evaluar los efectos de la entrevista motivacional en conjunto con una intervención cognitivo-conductual grupal. Participaron 25 pacientes con diagnóstico de dia-betes mellitus tipo 2 de una institución de salud pública. Los pacientes fueron distribuidos de manera intencional en dos grupos: uno que incluye una sesión de entrevista motivacional individual y el otro una sesión educativa individual. Ambas sesiones se realizaron antes y después de ingresar al t...

  2. CONTRIBUCION DEL CANAL TIPO TASK A LA HIPERREACTIVIDAD DEL CUERPO CAROTIDEO INDUCIDA POR HIPOXIA INTERMITENTE CRONICA

    OpenAIRE

    ORTIZ CISTERNAS; FERNANDO ANDRES

    2011-01-01

    El cuerpo carotídeo (CC) es el principal órgano quimiosensorial periférico que detecta los cambios en los niveles arteriales de P02, PC02 y pH. En respuesta a la hipoxia aguda las células quimiorreceptoras (tipo 1) del ce se despolarizan gatillando un aumento del ci+ intracelular y la concomitante liberación de uno o más neurotransmisores. Se ha propuesto que -al menos en ratas neonatas- esta despolarización se inicia con la inhibición por hipoxia de una corriente de K+ de...

  3. Estado nutricional del lactante de uno a seis meses y tipo de lactancia.

    OpenAIRE

    Ubillus, Gloria; Lamas, Cristina; Lescano, Beatriz; Levano, Melissa; Llerena, Zoila; Lopez, Rosa

    2011-01-01

    OBJETIVOIdentificar el estado nutricional de lactantes de uno a seis meses que acuden a consultorio externo en relación el tipo de lactancia..MATERIAL Y MÉTODOSe realizó un estudio observacional, descriptivo en el Instituto Nacional de Salud del Niño, centro de referencia nacional, entre Septiembre- Noviembre del 2007. Se seleccionó aleatoriamente 250 niños entre 1-6 meses de edad de ambos géneros, para ser estudiados en consultorios externos. Se evaluó las medidas de talla, peso y perímetro ...

  4. Influência do tipo de vidro de cobertura na produtividade do tomate em estufa

    OpenAIRE

    2015-01-01

    Mestrado em Engenharia Agronómica - Hortofruticultura e Viticultura - Instituto Superior de Agronomia - UL Foi realizado um ensaio, nas estufas de vidro da empresa Atlantic Growers, com o objetivo de comparar o efeito do grau de difusibilidade de três tipos de vidros, 45, 75 e liso, de cobertura na produtividade de uma cultura de tomate ao longo do período Dezembro-Maio. O tomate foi produzido em cultura sem solo, com substrato de lã de rocha, numa estufa de vidro aquecida, com adição de C...

  5. Caracterización de un modelo de diabetes tipo 2 en ratas Wistar hembra

    OpenAIRE

    2013-01-01

    RESUMENObjetivo. Caracterizar un modelo de diabetes mellitus tipo 2 (DM2) en ratas hembra. Materiales y métodos. Se utilizaron 20 ratas Wistar hembra de 48 horas de edad; a 10 se les administró estreptozotocina (STZ), [135 mg/kg de peso corporal] en 50 μl de amortiguador de citratos a pH de 4.5, vía intraperitoneal (inducidos) y a 10 se les administró 50 μl del amortiguador (testigo). Resultados. Los animales inducidos presentaron glicemias de 7.8±2 mmol/L (52.9% más que el testigo; p

  6. Tipo de cambio real y desalineamiento: teoría y evidencia para Ecuador

    OpenAIRE

    2009-01-01

    Determinar el Tipo de Cambio Real (TCR) respecto a algún estándar de equilibrio resulta fundamental para la política económica, ya que la información que ofrece este índice se refiere al grado de competitividad del sector transable con respecto al no transable, dentro de las fronteras de la economía ecuatoriana. El objetivo del presente estudio es, al observar la marcada apreciación del TCR desde el 2000, establecer un TCR que tenga en cuenta el equilibrio interno y externo, y determinar su ...

  7. FITOQUÍMICOS BIOATIVOS EM FRUTOS DE GENÓTIPOS DE CAJÁ-UMBUZEIRAS

    Directory of Open Access Journals (Sweden)

    Aldenise Chagas Curvêlo Gonçalves MOREIRA

    2012-04-01

    Full Text Available Com o objetivo de quantificar os fitoquímicos bioativos em cajá-umbu foram utilizadas polpas de frutos de 4 genótipos (G 2.2, G 2.3, G 3.1 e G 3.2 procedentes do Banco de Germoplasma do Instituto Agronômico de Pernambuco (IPA. Os teores de fenólicos, flavonoides e flavonóis totais e taninos condensados foram quantificados por método espectrofotométrico, de ácido ascórbico por método titulométrico e de carotenoides por método cromatográfico e espectrofotométrico. Os genótipos apresentaram teores de fenólicos totais de 110,61 a 188,86mg equivalente em ácido gálico 100g-1, flavonoides de 1,95 a 2,37mg em equivalente de catequina 100g-1, flavonóis de 2,59 a 2,80mg em equivalente de quercetina 100g-1 e taninos condensados de 42,77 a 48,24mg em equivalente de catequina 100g-1. Os frutos apresentaram baixos teores de ácido ascórbico (6,1 a 7,3mg 100g-1 e de carotenoides (6,67 a 11,44μg g-1. O β-caroteno-5,6-5’6’-diepóxido foi o componente majoritário dos genótipos G 2.2, G 2.3 e G 3.1, enquanto que a luteína-5,6 epóxido foi encontrada em maior quantidade no G 3.2. Assim, embora os frutos dos genótipos tenham exibido variações nos teores dos fitoquí- micos bioativos, apresentam em sua constituição quantidades relevantes destes compostos, podendo contribuir com o aporte de antioxidante dietético.

  8. Qualidade de vida e sintomas depressivos em adolescentes com Diabetes Mellitus tipo 1 (DM1)

    OpenAIRE

    Gabriela de Oliveira Pintar

    2015-01-01

    O objetivo geral deste trabalho foi avaliar a presença de sintomas depressivos e as possíveis influências do Diabetes Mellitus tipo I (DM1) na qualidade de vida de adolescentes com esta doença. Para alcançar tal objetivo foram avaliados adolescentes com DM1 (58) e sem DM1 (61) completando um total de 119 adolescentes avaliados; de ambos os sexos. Os locais de coleta de dados foram o Ambulatório de Endocrinologia da Criança e do Adolescente (ECA) do Hospital das Clínicas da Faculdade de Medici...

  9. EFECTO DEL TIPO Y CONTROLABILIDAD DEL ESTRÉS SOBRE LA CONDUCTA ALIMENTARIA EN RATAS

    OpenAIRE

    Marina Liliana González-Torres; Antonio López-Espinoza; Cristiano Valerio Dos Santos

    2010-01-01

    El objetivo del estudio fue evaluar los efectos de dos tipos de estrés, crónico o agudo, en situaciones de controlabilidad o incontrolabilidad sobre el peso corporal, consumo de alimento y agua en ratas. El estrés agudo constó de dos sesiones de 60 choques eléctricos y el crónico de 12 sesiones de 10 choques. Los sujetos expuestos a la situación controlable podían terminar el choque con una respuesta específica, y el incontrolable fue acoplado al anterior. El grupo control se mantuvo en su ca...

  10. Cariogenicidade de diferentes tipos de leite : efeito da suplementaçáo com ferro

    OpenAIRE

    Regina Celia Rocha Peres

    2000-01-01

    Resumo: Os objetivos deste trabalho foram avaliar a cariogenicidade de diferentes tipos de leite e o efeito cariostático do ferro, quando suplementado em uma fórmula infantil. O trabalho foi dividido em dois experimentos, utilizando um modelo animal de cárie sujeito a um alto desafio cariogênico. Nos dois experimentos foram utilizadas ratas Wistar spf (specific pathogen free) infectadas com Streptococus sobrínus e posteriormente dessalivadas. No experimento I, sessenta ratas foram divididas a...

  11. Caracterizaci??n de la rabia en el departamento central de Paraguay

    OpenAIRE

    1999-01-01

    Se brinda una visi??n de la problem??tica de la rabia de tipo urbano en el departamento Central, que es la predominante en esta regi??n del pa??s. Con este objetivo, son analizados los diagn??sticos laboratoriales en base a una muestra aleatoria, y otra muestra de las fichas de atenci??n a personas v??ctimas de agresiones producidas por animales en el departamento Central de Paraguay, entre los a??os 1992-1997. Es presentado adem??s el n??mero de casos de rabia humana entre 1992-1997, y algun...

  12. Carbonate complexation of Np(IV) in alkaline solutions

    Energy Technology Data Exchange (ETDEWEB)

    Kitamura, Akira [Japan Nuclear Cycle Development Inst., Tokai Works, Tokai, Ibaraki (Japan); Kohara, Yukitoshi [Inspection Development Company Ltd., Tokai, Ibaraki (Japan)

    2002-12-01

    Reliable thermodynamic data for actinide (IV) have been required. The solubility of Np(IV) in carbonate media was studied for determination of thermodynamic data. The concentration of dissolved Np(IV) was measured with ionic strengths from 0.5 to 2.9 M (M {identical_to} mol{center_dot}dm{sup -3}), hydrogen-ion concentration exponent (pH{sub c} = -log[H{sup +}]) from 8 to 13 and with the total carbonate concentration (C{sub T}) from 5x10{sup -3} M to 7x10{sup -1} M by an oversaturation method. It was found that the solubility of Np(IV) decreased with increasing pH{sub c} and increased with increasing C{sub T}. On the basis of analysis of the solubility data, the dominant aqueous species of Np(IV) were expected to be Np(CO{sub 3}){sub 4}{sup 4-}, Np(CO{sub 3}){sub 2}(OH){sub 2}{sup 2-} and Np(CO{sub 3}){sub 2}(OH){sub 4}{sup 4-} in the present study. The apparent equilibrium constants of the carbonate and carbonatohydroxo complexes were obtained in the respective ionic strength and the equilibrium constants at the zero ionic strength were extrapolated. The obtained equilibrium constants supported the literature values strongly, and contributed to improve the reliability of the thermodynamic data. (author)

  13. Astragaloside IV ameliorates renal injury in db/db mice

    Science.gov (United States)

    Sun, Huili; Wang, Wenjing; Han, Pengxun; Shao, Mumin; Song, Gaofeng; Du, Heng; Yi, Tiegang; Li, Shunmin

    2016-09-01

    Diabetic nephropathy is a lethal complication of diabetes mellitus and a major type of chronic kidney disease. Dysregulation of the Akt pathway and its downstream cascades, including mTOR, NFκB, and Erk1/2, play a critical role in the development of diabetic nephropathy. Astragaloside IV is a major component of Huangqi and exerts renal protection in a mouse model of type 1 diabetes. The current study was undertaken to investigate the protective effects of diet supplementation of AS-IV on renal injury in db/db mice, a type 2 diabetic mouse model. Results showed that administration of AS-IV reduced albuminuria, ameliorated changes in the glomerular and tubular pathology, and decreased urinary NAG, NGAL, and TGF-β1 in db/db mice. AS-IV also attenuated the diabetes-related activation of Akt/mTOR, NFκB, and Erk1/2 signaling pathways without causing any detectable hepatotoxicity. Collectively, these findings showed AS-IV to be beneficial to type 2 diabetic nephropathy, which might be associated with the inhibition of Akt/mTOR, NFκB and Erk1/2 signaling pathways.

  14. Solar neutrino measurements in Super-Kamiokande-IV

    Science.gov (United States)

    Abe, K.; Haga, Y.; Hayato, Y.; Ikeda, M.; Iyogi, K.; Kameda, J.; Kishimoto, Y.; Marti, Ll.; Miura, M.; Moriyama, S.; Nakahata, M.; Nakajima, T.; Nakayama, S.; Orii, A.; Sekiya, H.; Shiozawa, M.; Sonoda, Y.; Takeda, A.; Tanaka, H.; Takenaga, Y.; Tasaka, S.; Tomura, T.; Ueno, K.; Yokozawa, T.; Akutsu, R.; Irvine, T.; Kaji, H.; Kajita, T.; Kametani, I.; Kaneyuki, K.; Lee, K. P.; Nishimura, Y.; McLachlan, T.; Okumura, K.; Richard, E.; Labarga, L.; Fernandez, P.; Blaszczyk, F. d. M.; Gustafson, J.; Kachulis, C.; Kearns, E.; Raaf, J. L.; Stone, J. L.; Sulak, L. R.; Berkman, S.; Tobayama, S.; Goldhaber, M.; Bays, K.; Carminati, G.; Griskevich, N. J.; Kropp, W. R.; Mine, S.; Renshaw, A.; Smy, M. B.; Sobel, H. W.; Takhistov, V.; Weatherly, P.; Ganezer, K. S.; Hartfiel, B. L.; Hill, J.; Keig, W. E.; Hong, N.; Kim, J. Y.; Lim, I. T.; Park, R. G.; Akiri, T.; Albert, J. B.; Himmel, A.; Li, Z.; O'Sullivan, E.; Scholberg, K.; Walter, C. W.; Wongjirad, T.; Ishizuka, T.; Nakamura, T.; Jang, J. S.; Choi, K.; Learned, J. G.; Matsuno, S.; Smith, S. N.; Friend, M.; Hasegawa, T.; Ishida, T.; Ishii, T.; Kobayashi, T.; Nakadaira, T.; Nakamura, K.; Nishikawa, K.; Oyama, Y.; Sakashita, K.; Sekiguchi, T.; Tsukamoto, T.; Nakano, Y.; Suzuki, A. T.; Takeuchi, Y.; Yano, T.; Cao, S. V.; Hayashino, T.; Hiraki, T.; Hirota, S.; Huang, K.; Ieki, K.; Jiang, M.; Kikawa, T.; Minamino, A.; Murakami, A.; Nakaya, T.; Patel, N. D.; Suzuki, K.; Takahashi, S.; Wendell, R. A.; Fukuda, Y.; Itow, Y.; Mitsuka, G.; Muto, F.; Suzuki, T.; Mijakowski, P.; Frankiewicz, K.; Hignight, J.; Imber, J.; Jung, C. K.; Li, X.; Palomino, J. L.; Santucci, G.; Taylor, I.; Vilela, C.; Wilking, M. J.; Yanagisawa, C.; Fukuda, D.; Ishino, H.; Kayano, T.; Kibayashi, A.; Koshio, Y.; Mori, T.; Sakuda, M.; Takeuchi, J.; Yamaguchi, R.; Kuno, Y.; Tacik, R.; Kim, S. B.; Okazawa, H.; Choi, Y.; Ito, K.; Nishijima, K.; Koshiba, M.; Totsuka, Y.; Suda, Y.; Yokoyama, M.; Bronner, C.; Calland, R. G.; Hartz, M.; Martens, K.; Obayashi, Y.; Suzuki, Y.; Vagins, M. R.; Nantais, C. M.; Martin, J. F.; de Perio, P.; Tanaka, H. A.; Konaka, A.; Chen, S.; Sui, H.; Wan, L.; Yang, Z.; Zhang, H.; Zhang, Y.; Connolly, K.; Dziomba, M.; Wilkes, R. J.; Super-Kamiokande Collaboration

    2016-09-01

    Upgraded electronics, improved water system dynamics, better calibration and analysis techniques allowed Super-Kamiokande-IV to clearly observe very low-energy 8B solar neutrino interactions, with recoil electron kinetic energies as low as ˜3.5 MeV . Super-Kamiokande-IV data-taking began in September of 2008; this paper includes data until February 2014, a total livetime of 1664 days. The measured solar neutrino flux is (2.308 ±0.020 (stat)-0.040 +0.039(syst ))×1 06/(cm2 sec ) assuming no oscillations. The observed recoil electron energy spectrum is consistent with no distortions due to neutrino oscillations. An extended maximum likelihood fit to the amplitude of the expected solar zenith angle variation of the neutrino-electron elastic scattering rate in SK-IV results in a day/night asymmetry of (-3.6 ±1.6 (stat )±0.6 (syst ))% . The SK-IV solar neutrino data determine the solar mixing angle as sin2θ12=0.327-0.031+0.026 , all SK solar data (SK-I, SK-II, SK III and SK-IV) measures this angle to be sin2θ12=0.334-0.023+0.027 , the determined mass-squared splitting is Δ m212=4.8-0.8+1.5×10-5 eV2 .

  15. Does WISC-IV Underestimate the Intelligence of Autistic Children?

    Science.gov (United States)

    Nader, Anne-Marie; Courchesne, Valérie; Dawson, Michelle; Soulières, Isabelle

    2016-05-01

    Wechsler Intelligence Scale for Children (WISC) is widely used to estimate autistic intelligence (Joseph in The neuropsychology of autism. Oxford University Press, Oxford, 2011; Goldstein et al. in Assessment of autism spectrum disorders. Guilford Press, New York, 2008; Mottron in J Autism Dev Disord 34(1):19-27, 2004). However, previous studies suggest that while WISC-III and Raven's Progressive Matrices (RPM) provide similar estimates of non-autistic intelligence, autistic children perform significantly better on RPM (Dawson et al. in Psychol Sci 18(8):657-662, doi: 10.1111/j.1467-9280.2007.01954.x , 2007). The latest WISC version introduces substantial changes in subtests and index scores; thus, we asked whether WISC-IV still underestimates autistic intelligence. Twenty-five autistic and 22 typical children completed WISC-IV and RPM. Autistic children's RPM scores were significantly higher than their WISC-IV FSIQ, but there was no significant difference in typical children. Further, autistic children showed a distinctively uneven WISC-IV index profile, with a "peak" in the new Perceptual Reasoning Index. In spite of major changes, WISC-IV FSIQ continues to underestimate autistic intelligence.

  16. Effect of bowel obstruction on stage IV colorectal cancer.

    Science.gov (United States)

    Chen, Wei; Tan, Xiao-Ping; Ye, Jun-Wen; Liu, Qin; Zeng, Qingli; Wang, Lei; Wang, Jian-Ping

    2014-03-01

    Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide, with a high mortality rate, particularly among patients with advanced-stage disease complicated by bowel obstruction. The present study aimed to investigate the value of different surgical procedures and potential predictors of survival for patients with stage IV CRC, with or without bowel obstruction. Between August, 1994 and December, 2005, a total of 2,950 CRC patients were diagnosed and treated at our hospital. Among these, 381 patients had stage IV disease and were divided into two groups according to the presence (n=295) or absence (n=86) of bowel obstruction. The clinical data of all the patients with stage IV CRC were retrospectively analyzed and all the patients were followed up. Our results demonstrated statistically significant differences in gender, radical resection, histological type, ascites, tumor location, peritoneal and liver metastases between the obstruction and non-obstruction groups. We also observed that hepatic metastases and radical resection were factors associated with prognosis according to the univariate and multivariate analyses. Furthermore, the mean/median survival time was 49.4/21.6 and 37.2/17.1 months in the non-obstruction and obstruction groups, respectively. In conclusion, obstruction was not found to be an independent indicator of survival for patients with stage IV CRC, with patients in the obstruction group exhibiting a worse overall survival compared to those in the non-obstruction group, whereas active radical surgery significantly improved the prognosis of patients with stage IV CRC.

  17. The central peak revisited

    Energy Technology Data Exchange (ETDEWEB)

    Shirane, G.

    1995-10-27

    The central peak in SrTiO{sub 3} was first observed by Riste and his collaborators in 1971. This was one of the key discoveries leading to an understanding of the dynamics of phase transitions. The most recent discovery of two length scales in SrTiO{sub 3} motivated a reinvestigation of the soft phonon and associated central peak by neutron scattering. These recent experiments shed new light on the nature of the central peak. It is now well established to be strongly sample dependent and it originates from defects in bulk crystals.

  18. Imaging central pain syndromes.

    Science.gov (United States)

    Veldhuijzen, Dieuwke S; Greenspan, Joel D; Kim, Jong H; Coghill, Robert C; Treede, Rolf-Detlef; Ohara, Shinji; Lenz, Frederick A

    2007-06-01

    Anatomic, functional, and neurochemical imaging studies have provided new investigative tools in the study of central pain. High-resolution imaging studies allow for precise determination of lesion location, whereas functional neuroimaging studies measure pathophysiologic consequences of injury to the central nervous system. Additionally, magnetic resonance spectroscopy evaluates lesion-induced neurochemical changes in specific brain regions that may be related to central pain. The small number of studies to date precludes definitive conclusions, but the recent findings provide information that either supports or refutes current hypotheses and can serve to generate new ideas.

  19. A COMPARATIVE CLINICAL STUDY BETWEEN IV ESMOLOL AND IV FENTANYL ON ATTENUATION OF HAEMODYNAMIC RESPONSES TO LARYNGOSCOPY AND INTUBATION

    Directory of Open Access Journals (Sweden)

    Abu Lais Mustaque

    2016-04-01

    Full Text Available INTRODUCTION Laryngoscopy and intubation is an integral part for providing general anaesthesia to patients undergoing various types of surgery. It also plays an important role in critical care units viz. for providing mechanical ventilation. It is a very essential tool in the hands of anaesthesiologist in maintaining airway. The present study is undertaken to determine and compare the efficacy of single bolus dose of IV esmolol 1 mg/kg and IV fentanyl 2 mcg/kg in attenuating the haemodynamic responses to laryngoscopy and tracheal intubation and to ascertain the effectiveness of esmolol hydrochloride and fentanyl citrate in suppressing sympathetic responses. MATERIAL & METHODS The study was conducted under the Department of Anaesthesiology and Critical Care, Assam Medical College and Hospital, Dibrugarh, during the period July 2013 to June 2014. For this purpose, 150 patients of either sex between 20-50 years of ASA I & II physical status were selected after obtaining informed and written consent and were divided into two groups namely, Group E receiving IV esmolol (1 mg/kg and Group F receiving IV fentanyl (2 mcg/kg. RESULTS Inj. fentanyl 2 mcg/kg IV administered 5 minutes before laryngoscopy and intubation was able to prevent adverse haemodynamic changes better than Inj. esmolol 1 mg/kg IV administered 3 minutes prior to laryngoscopy and intubation during elective surgeries under general anaesthesia. CONCLUSION Hence, from the findings of this study we can conclude that IV bolus dose of fentanyl 2 mcg/kg administered 5 minutes before laryngoscopy and intubation can attenuate the sympathetic response to laryngoscopy and intubation without any side effects of the drug in healthy patients undergoing elective surgeries under general anaesthesia.

  20. Structural characterization of outer membrane components of the type IV pili system in pathogenic Neisseria.

    Directory of Open Access Journals (Sweden)

    Samta Jain

    Full Text Available Structures of the type IV pili secretin complexes from Neisseria gonorrhoeae and Neisseria meningitidis, embedded in outer membranes were investigated by transmission electron microscopy. Single particle averaging revealed additional domains not observed previously. Secretin complexes of N. gonorrhoeae showed a double ring structure with a 14-15-fold symmetry in the central ring, and a 14-fold symmetry of the peripheral ring with 7 spikes protruding. In secretin complexes of N. meningitidis, the spikes were absent and the peripheral ring was partly or completely lacking. When present, it had a 19-fold symmetry. The structures of the complexes in several pil mutants were determined. Structures obtained from the pilC1/C2 adhesin and the pilW minor pilin deletion strains were similar to wild-type, whereas deletion of the homologue of N. meningitidis PilW resulted in the absence of secretin structures. Remarkably, the pilE pilin subunit and pilP lipoprotein deletion mutants showed a change in the symmetry of the peripheral ring from 14 to 19 and loss of spikes. The pilF ATPase mutant also lost the spikes, but maintained 14-fold symmetry. These results show that secretin complexes contain previously unidentified large and flexible extra domains with a probable role in stabilization or assembly of type IV pili.

  1. A type IV pilus mediates DNA binding during natural transformation in Streptococcus pneumoniae.

    Directory of Open Access Journals (Sweden)

    Raphaël Laurenceau

    Full Text Available Natural genetic transformation is widely distributed in bacteria and generally occurs during a genetically programmed differentiated state called competence. This process promotes genome plasticity and adaptability in Gram-negative and Gram-positive bacteria. Transformation requires the binding and internalization of exogenous DNA, the mechanisms of which are unclear. Here, we report the discovery of a transformation pilus at the surface of competent Streptococcus pneumoniae cells. This Type IV-like pilus, which is primarily composed of the ComGC pilin, is required for transformation. We provide evidence that it directly binds DNA and propose that the transformation pilus is the primary DNA receptor on the bacterial cell during transformation in S. pneumoniae. Being a central component of the transformation apparatus, the transformation pilus enables S. pneumoniae, a major Gram-positive human pathogen, to acquire resistance to antibiotics and to escape vaccines through the binding and incorporation of new genetic material.

  2. Substitutional disorder in bis[(cyanato-κO/hydroxido(0.5/0.5](5,10,15,20-tetraphenylporphyrinato-κ4Ntin(IV

    Directory of Open Access Journals (Sweden)

    Imen Ben Moussa

    2011-07-01

    Full Text Available The title complex, [SnIV(C44H28N4(CNO(OH], exhibits substitutional disorder of the OH− and OCN− axial ligands. Thus, the cyanato-O ligand and the hydroxyl group bonded to the central SnIV atom share statistically the axial position. The SnIV ion is hexacoordinated by the four N atoms of the pyrrole rings of the tetraphenylporphyrin (TPP and the O atoms of the two disordered OCN− and OH− axial ligands. The equatorial tin–pyrrole N atom distance (Sn—Np is 2.100 (2 Å and the axial Sn—O(OCN or Sn—O(OH bond length is 2.074 (2 Å.

  3. Central nervous system resuscitation

    DEFF Research Database (Denmark)

    McIntosh, T K; Garde, E; Saatman, K E;

    1997-01-01

    Traumatic injury to the central nervous system induces delayed neuronal death, which may be mediated by acute and chronic neurochemical changes. Experimental identification of these injury mechanisms and elucidation of the neurochemical cascade following trauma may provide enhanced opportunities ...

  4. Central Asian Republic Info

    Data.gov (United States)

    US Agency for International Development — CAR Info is designed and managed by the Central Asian Republic Mission to fill in the knowledge and reporting gaps in existing agency systems for that Mission. It...

  5. Central nervous system

    Science.gov (United States)

    The central nervous system is composed of the brain and spinal cord. Your brain and spinal cord serve as the main "processing center" for your entire nervous system. They control all the workings of your body.

  6. Central nervous system resuscitation

    DEFF Research Database (Denmark)

    McIntosh, T K; Garde, E; Saatman, K E

    1997-01-01

    Traumatic injury to the central nervous system induces delayed neuronal death, which may be mediated by acute and chronic neurochemical changes. Experimental identification of these injury mechanisms and elucidation of the neurochemical cascade following trauma may provide enhanced opportunities...

  7. "Central Station" Londonis

    Index Scriptorium Estoniae

    2000-01-01

    Londoni galeriis Milch seitsme läti, leedu ja eesti kunstniku projekt "Central Station". Kuraatorid Lisa Panting, Sally Tallant. Eestist osalevad Hanno Soans (Catarina Campinoga koostöös valminud video), Kiwa, Kai Kaljo

  8. Central Station Design Options

    DEFF Research Database (Denmark)

    2011-01-01

    The purpose of EDISON Work Package 4.1 is the evaluation of possible Central (charging) Stations design options for making possible the public charging of Electric Vehicles (EVs). A number of scenarios for EVs are assessed, with special emphasis on the options of Fast Charging and Battery Swapping....... The work identifies the architecture, sizing and siting of prospective Central Stations in Denmark, which can be located at shopping centers, large car parking lots or gas stations. Central Stations are planned to be integrated in the Danish distribution grid. The Danish island of Bornholm, where a high.......g. due to vandalism, the charge supply circuit is disconnected. More electrical vehicles on the market are capable today of quick charging up to 50 kW power level. The feasibility of Central Stations with fast charging/swapping option, their capacity, design, costs and grid impact, as well as battery...

  9. Coordination Chemistry of Homoleptic Actinide(IV)-Thiocyanate Complexes.

    Science.gov (United States)

    Carter, Tyler J; Wilson, Richard E

    2015-10-26

    The synthesis, X-ray crystal structure, vibrational and optical spectroscopy for the eight-coordinate thiocyanate compounds, [Et4 N]4 [Pu(IV) (NCS)8 ], [Et4 N]4 [Th(IV) (NCS)8 ], and [Et4 N]4 [Ce(III) (NCS)7 (H2 O)] are reported. Thiocyanate was found to rapidly reduce plutonium to Pu(III) in acidic solutions (pHcoordination in acetonitrile based on the observation of intense ligand-to-metal charge-transfer bands. Spectroscopic and crystallographic data do not support the interaction of the metal orbitals with the ligand π system, but support an enhanced An(IV) -NCS interaction, as the Lewis acidity of the metal ion increases from Th to Pu.

  10. Court Culture during the Reign of Christian IV

    DEFF Research Database (Denmark)

    Olden-Jørgensen, Sebastian

    2007-01-01

    Court culture can be defined as a range of cultural forms (festival culture, painting, literature, music, architecture) employed for the enhancement of princely status and the communication of political messages. Christian IV evidently set great store on court culture beginning with his magnificent...... coronation in 1596, reaching a climax with the "great wedding" (of crown prince Christian) in 1634 and at last colapsing during the military and political crisis in the last years of his long reign (1588/96-1648). Danish court culture during the reign of Christian IV decidedly was on an European level......, and during the Thirty Years War he could even profit from the plight of fellow princes in germany and engage top artists like the composer Heinrich Schütz. The court culture of Christian IV was a succes in the sense that during the first part of his reign it underscored his success and status. During...

  11. Relative subtest scatter in the WAIS-IV standardization sample.

    Science.gov (United States)

    Binder, Laurence M; Binder, Adrienne L

    2011-01-01

    The frequencies of differences between highest and lowest subtest scores as a function of highest subtest score (relative scatter), are reported for the standardization sample of the Wechsler Adult Intelligence Scale-IV (WAIS-IV). Large differences between highest and lowest subtest scores were common. The degree of relative scatter was related to the height of the highest subtest score. For the 10 core WAIS-IV subtests, the correlation between the level of the highest subtest score and the amount of scatter was r = .62; for all 15 subtests the correlation was. 63. The level of the highest subtest score was more strongly related to scatter than was Full Scale IQ. Clinical implications for inferring cognitive impairment and estimating premorbid abilities are discussed. When considering the possibility of acquired cognitive impairment, we recommend caution in the interpretation of subtest score differences.

  12. The SDSS-IV in 2014: A Demographic Snapshot

    CERN Document Server

    Lundgren, Britt; Zasowski, Gail; Lucatello, Sara; Diamond-Stanic, Aleksandar M; Tremonti, Christy A; Myers, Adam D; Aragon-Salamanca, Alfonso; Gillespie, Bruce; Ho, Shirley; Gallagher, John S

    2015-01-01

    Many astronomers now participate in large international collaborations, and it is important to examine whether these structures foster a scientific climate that is inclusive and diverse. The Committee on the Participation of Women in the Sloan Digital Sky Survey (CPWS) was formed to evaluate the demographics and gender climate within SDSS-IV, one of the largest and most geographically distributed astronomical collaborations. In April 2014, the CPWS administered a demographic survey to establish a baseline for the incipient SDSS-IV. We received responses from 250 participants (46% of the active membership). Half of the survey respondents were located in the US or Canada and 30% were based in Europe. Eleven percent of survey respondents considered themselves to be an ethnic minority at their current institution. Twenty-five percent of the SDSS-IV collaboration members are women, a fraction that is consistent with the US astronomical community, but substantially higher than the fraction of women in the IAU (16%)...

  13. In-line filters in central venous catheters in a neonatal intensive care unit

    NARCIS (Netherlands)

    van den Hoogen, A; Krediet, TG; Uiterwaal, CSPM; Bolenius, JFGA; Gerards, LJ; Fleer, A

    2006-01-01

    Nosocomial sepsis remains an important cause of morbidity in neonatal intensive care units. Central venous catheters (CVCs) and parenteral nutrition (TPN) are major risk factors. In-line filters in the intravenous (IV) administration sets prevent the infusion of particles, which may reduce infectiou

  14. Hydration and hydrolysis of thorium(IV) in aqueous solution and the structures of two crystalline thorium(IV) hydrates.

    Science.gov (United States)

    Torapava, Natallia; Persson, Ingmar; Eriksson, Lars; Lundberg, Daniel

    2009-12-21

    Solid octaaqua(kappa(2)O-perchlorato)thorium(IV) perchlorate hydrate, [Th(H(2)O)(8)(ClO(4))](ClO(4))(3).H(2)O, 1, and aquaoxonium hexaaquatris(kappaO-trifluoromethanesulfonato)thorium(IV) trisaquahexakis(kappaO-trifluoromethanesulfonato)thorinate(IV), H(5)O(2)[Th(H(2)O)(6)(OSO(2)CF(3))(3)][Th(H(2)O)(3)(OSO(2)CF(3))(6)], 2, were crystallized from concentrated perchloric and trifluoromethanesulfonic acid solutions, respectively. 1 adopts a severely distorted tricapped trigonal prismatic configuration with an additional oxygen from the perchlorate ion at a longer distance. 2 consists of individual hexaaquatris(kappaO-trifluoromethanesulfonato)thorium(IV) and trisaquahexakis(kappaO-trifluoromethanesulfonato)thorinate(IV) ions and an aquaoxonium ion bridging these two ions through hydrogen bonding. The hydrated thorium(IV) ion is nine-coordinated in aqueous solution as determined by extended X-ray absorption fine structure (EXAFS) and large angle X-ray scattering (LAXS). The LAXS studies also showed a second hydration sphere of about 18 water molecules, and traces of a 3rd hydration sphere. Structural studies in aqueous solution of the hydrolysis products of thorium(IV) have identified three different types of hydrolysis species: a mu(2)O-hydroxo dimer, [Th(2)(OH)(2)(H(2)O)(12)](6+), a mu(2)O-hydroxo tetramer, [Th(4)(OH)(8)(H(2)O)(16)](8+), and a mu(3)O-oxo hexamer, [Th(6)O(8)(H(2)O)(n)](8+). Detailed structures of these three hydrolysis species are given. A compilation of reported solid state structures of actinoid(IV) compounds with oxygen donor ligands show a strong correlation between the An-O bond distance and the coordination number. The earlier reported U-O bond distance in the hydrated uranium(IV) ion in aqueous solution, confirmed in this study, is related to nine-coordination. The hydrated tri- and tetravalent actinoid ions in aqueous solution all seem to be nine-coordinated. The trivalent ions show a significant difference in bond distance to prismatic and

  15. Gangs in Central America

    Science.gov (United States)

    2008-10-17

    Citizen Security held in July 2008 indicated that Guatemala now has the second highest murder rate in Central America (roughly 45 per 100,000 people...training regional security forces.48 In recent years, the U.S. Southern Command has taken a leading role in discussing the problem of citizen security in...the results CRS-19 51 “Memo: The Merida Initiative and Citizen Security in Mexico and Central America,” Washington Office on Latin America, March 2008

  16. Outsourcing central banking

    DEFF Research Database (Denmark)

    Khoury, Sarkis Joseph; Wihlborg, Clas

    2005-01-01

    The literature on Currency Boards (CB) stops at the water edge in terms of dealing with the totality of the functions of a central bank. Monetary policy, and banking supervisioncan be "outsourced" in an open economy with substantial foreign direct investment (FDI)in the banking sector if political...... the feasibility of, and constraints on, outsourcing of central bank functions. A brief discussion of the Argentinian experience is used for contrast.Key words: Currency Board, Foreign Banks, Supervision, Regional Integration,outsourcing....

  17. J-Integral characterization of the nozzle steels from intermediate test vessels IV-5 and IV-9

    Energy Technology Data Exchange (ETDEWEB)

    Auten, T.A.; Macdonald, B.D.; Scavone, D.W.; Bozik, D.

    1994-10-01

    Reported here are the results of elastic-plastic fracture toughness tests performed on low alloy steels from the nozzles of the intermediate test vessels IV-5 and IV-9 from the Heavy Steel Section Technology Program at Oak Ridge National Laboratory. These vessels had been given prototypic nozzle corner flaw tests prior to the development of the ASTM E-813 standard test procedure for J-integral testing. The objective of this work is to provide J-integral material test support for future elastic-plastic fracture mechanics analysis of the nozzles. J-integral tests at 88{degrees}C (190{degrees}F) of the IV-5 nozzle material produced stable ductile tearing. The tearing resistance data are expected to support analysis of the observed similar stable tearing response of the nozzle corner flaw. J-integral tests at 24{degrees}C (75{degrees}F) of the IV-9 nozzle produced elastic-plastic fracture instability preceded by stable tearing. A similar response was observed in the IV-9 nozzle corner flaw test. It will be a major and important challenge to develop a fracture mechanics rationale that reconciles these small specimen and nozzle corner flaw test results. These test results are being made available to allow their use by a wide variety of organizations in developing such a rationale, which would be a significant contribution to quantifying the flaw tolerance of reactor pressure vessels.

  18. Tethys and Annex IV Progress Report for FY 2012

    Energy Technology Data Exchange (ETDEWEB)

    Hanna, Luke A.; Butner, R. Scott; Whiting, Jonathan M.; Copping, Andrea E.

    2013-09-01

    The marine and hydrokinetic (MHK) environmental Impacts Knowledge Management System, dubbed “Tethys” after the mythical Greek titaness of the seas, is being developed by the Pacific Northwest National Laboratory (PNNL) to support the U.S. Department of Energy’s Wind and Water Power Program (WWPP). Functioning as a smart database, Tethys enables its users to identify key words or terms to help gather, organize and make available information and data pertaining to the environmental effects of MHK and offshore wind (OSW) energy development. By providing and categorizing relevant publications within a simple and searchable database, Tethys acts as a dissemination channel for information and data which can be utilized by regulators, project developers and researchers to minimize the environmental risks associated with offshore renewable energy developments and attempt to streamline the permitting process. Tethys also houses a separate content-related Annex IV data base with identical functionality to the Tethys knowledge base. Annex IV is a collaborative project among member nations of the International Energy Agency (IEA) Ocean Energy Systems – Implementing Agreement (OES-IA) that examines the environmental effects of ocean energy devices and projects. The U.S. Department of Energy leads the Annex IV working with federal partners such as the Federal Energy Regulatory Commission (FERC), the Bureau of Ocean Energy Management (BOEM), and the National Oceanic Atmospheric Administration (NOAA). While the Annex IV database contains technical reports and journal articles, it is primarily focused on the collection of project site and research study metadata forms (completed by MHK researchers and developers around the world, and collected by PNNL) which provide information on environmental studies and the current progress of the various international MHK developments in the Annex IV member nations. The purpose of this report is to provide a summary of the content

  19. Siringomielia asociado a Malformación de Chiari tipo I

    Directory of Open Access Journals (Sweden)

    Dr. Ladislao Flores Alvis

    2012-12-01

    Full Text Available La Siringomielia asociada a Malformación de Chiari tipo I, se refiere a una cavidad formada en la médula espinal debido a la obstrucción del canal medular por el desplazamiento de las amígdalas cerebelosas hacia el agujero magno, manifestándose entre los 25-40 años, con cuadros progresivos de dorsalgias, cervicalgias, dolor de extremidades uni-bilateral, pérdida de sensibilidad; dependiendo del tamaño de la cavidad, la medula espinal puede comprimirse y generar la lesión irreversible de la médula espinal.Se presenta un caso clínico de Siringomielia asociada a Malformación de Chiari tipo I; que presentó cuadro clínico de larga data previa a su diagnóstico; caracterizado por dorsalgias recurrentes que fueron tratadas con diclofenaco y complejo B, pensando en problema muscular. Se le diagnostica por resonancia magnética (RM, y el tratamiento fue la descompresión de fosa posterior; un año después de su tratamiento quirúrgico se le realiza una RM de control donde hay ausencia de la Siringomielia

  20. MULHER, UMA CONSTRUÇÃO SOCIAL: REPRESENTAÇÕES, ESTEREÓTIPOS E IMAGENS

    Directory of Open Access Journals (Sweden)

    Rosana Rocha Siqueira

    2014-06-01

    Full Text Available O presente artigo tem como objetivo uma revisita a referenciais bibliográficos a partir dos quais foi possível refletir sobre a construção de estereótipos relacionados à imagem feminina no século XX partindo-se do conceito de representação proposto por Moscovici (2003. Pretende-se na convergência destas duas categorias (representação e imagem apresentar olhares sobre a construção de alguns estereótipos relacionados às mulheres, uma vez que diversas instituições inclusive o próprio movimento feminista em suas variadas vertentes também preocuparam-se em “criar” representações das mulheres. Algumas discussões presentes neste artigo fizeram parte do conteúdo da disciplina “Seminários avançados sobre produtos, processos e discursos midiáticos” ofertada pelo Núcleo de Pós-Graduação da Universidade Federal de Sergipe. Desta forma pode-se refletir sobre os variados recortes imagéticos dos quais as instituições e as próprias mulheres utilizaram-se para compor novas representações.

  1. ¿QUÉ ESCRIBEN LOS ESTUDIANTES DE POSGRADO? TIPOS DE TEXTOS SOLICITADOS EN SEMINARIOS

    Directory of Open Access Journals (Sweden)

    Laura Colombo

    2013-01-01

    Full Text Available El tema “tipos de textos solicitados a los alumnos en sus carreras universitarias” ha sido objeto de varias investigaciones, pero pocas se han centrado en el nivel de posgrado. En este trabajo, mediante una encuesta hecha a 118 participantes, indagamos el punto de vista de los estudiantes de maestrías y doctorados en diversas disciplinas. Los resultados muestran que existen diferencias entre programas de las facultades de artes, humanidades y ciencias sociales; ingeniería y tecnología de la información, y ciencias naturales y matemáticas. A excepción del abstract o resumen, los textos frecuentemente solicitados divergen de aquellos que se escribirán una vez finalizados los estudios. Resalta la poca frecuencia con que se piden artículos para revistas científicas (principal tipo de escrito que se utiliza en todas las disciplinas. Estudios como el aquí propuesto pueden impulsar futuras investigaciones sobre los programas de posgrado y su articulación con el ámbito profesional o académico.

  2. Cuotas de género y tipo de lista en América Latina

    Directory of Open Access Journals (Sweden)

    Nélida Archenti

    2007-06-01

    Full Text Available Las reformas electorales llevadas a cabo en algunos países de América Latina, a partir de los '90, han producido resultados cuyo análisis es ineludible para la comprensión del acceso de las mujeres a los cargos electivos. En la actualidad, no existe un consenso respecto a cómo afectan los elementos del sistema electoral a la participación política femenina bajo las leyes de cuotas, en particular en lo referente al tipo de lista (bloqueada o desbloqueada y la magnitud de distrito. Este artículo intenta, a través del análisis de los resultados electorales de esas provincias, aportar nuevos elementos empíricos al debate sobre los efectos del tipo de lista en el acceso de las mujeres a los legislativos, en sistemas con cuotas de género.The electoral reforms implemented in some Latin American countries at the 90's have had a strong impact over the women access to elected positions, although there is not a consensus about the electoral systems ' components that affect the women participation in politics through especific electoral laws. This article analyses the effects of electoral mechanisms on women's participation in politics in some municiaplities in Argentina.

  3. Tipos polínicos coletados por Nannotrigona testaceicornis e Tetragonisca angustula (Hymenoptera, Apidae, Meliponinae

    Directory of Open Access Journals (Sweden)

    Carvalho Carlos Alfredo Lopes de

    1999-01-01

    Full Text Available Os tipos polínicos coletados no mesmo pasto apícola por Nannotrigona testaceicornis e Tetragonisca angustula (Hymenoptera, Apidae, Meliponinae foram estudados e comparados durante dois meses em Piracicaba-SP, (22o43'S; 47o25'W; altitude: 580m. As massas de pólen foram obtidas através da captura de operárias que retornavam à colônia das 5:00 às 19:00 horas nos meses de outubro e novembro de 1996. Trinta e um tipos polínicos pertencentes a 22 famílias foram identificados, dos quais 22,58% foram coletados exclusivamente por N. testaceicornis, 35,48% por T. angustula e 41,94%, por ambas as espécies. As famílias Fabaceae, Liliaceae, Mimosaceae e Myrtaceae e as espécies Bulbine frutescens, Eucalyptus spp., Leucaena leucocephala e Tipuana tipu foram as mais freqüentes e constantes durante os trabalhos. O índice de similaridade entre as fontes de pólen explorada pelas abelhas foi igual a 0,78.

  4. Armazenamento refrigerado de beterraba minimamente processada em diferentes tipos de corte

    Directory of Open Access Journals (Sweden)

    Kluge Ricardo Alfredo

    2006-01-01

    Full Text Available Beterrabas minimamente processadas apresentam vida de prateira curta, mesmo sob refrigeração, devido à descoloração superficial que deprecia a qualidade do produto. O objetivo do trabalho foi verificar o efeito de três tipos de corte em beterraba minimamente avaliando sua qualidade durante a conservação refrigerada. Os cortes utilizados foram: fatia, cubo e retalho. Após o processamento as beterrabas foram armazenadas a 5degreesC e as avaliações sendo realizadas durante dez dias a cada dois dias. Beterrabas em fatias apresentaram maior respiração e maiores perdas dos pigmentos betalaínas e de sólidos solúveis durante o armazenamento. Através de análise sensorial, verificou-se que a qualidade visual do produto foi mantida por até quatro dias, independente do tipo de corte. O fator que mais depreciou a qualidade de beterraba minimamente processada foi a perda de coloração das raízes (esbranquiçamento. Pode-se concluir que a beterraba minimamente processada em fatias ou cubo apresenta conservação de, no máximo 4 dias, a 5degreesC, enquanto minimamente processada em retalho apresenta 6 dias de conservação.

  5. Fenótipos clínicos de asma grave Clinical phenotypes of severe asthma

    Directory of Open Access Journals (Sweden)

    Roseliane de Souza Araújo Alves

    2008-09-01

    Full Text Available OBJETIVO: Estabelecer os fenótipos clínicos em portadores de asma grave. MÉTODOS: Foram estudados, retrospectivamente, 111 pacientes em um ambulatório especializado. Os pacientes foram avaliados e acompanhados de maneira sistemática, estabelecendo-se ao final do acompanhamento a adesão e o controle ou não da doença por dados clínicos e funcionais. A resistência ao tratamento foi definida como o não preenchimento, ao final do acompanhamento, por pelo menos seis meses, dos critérios de controle de asma, apesar do uso correto e adesão à medicação. Os fenótipos foram determinados por análise fatorial e comparados por testes diversos. RESULTADOS: Ao final, 88 pacientes foram considerados aderentes e 23 não aderentes. Por análise fatorial do grupo aderente, quatro fenótipos foram determinados: o fenótipo 1 (28 pacientes, formado pelos pacientes resistentes ao tratamento, com maior freqüência de sintomas noturnos, maior número de exacerbações e uso mais freqüente de broncodilatador de resgate; o fenótipo 2 (48 pacientes, formado pelos pacientes com obstrução persistente, com menores valores de relação volume expiratório forçado no primeiro segundo/capacidade vital forçada na avaliação inicial, idade mais avançada e maior tempo de doença; o fenótipo 3 (42 pacientes, representa os pacientes com rinossinusite alérgica, sendo constituído de não fumantes com obstrução predominantemente reversível; e o fenótipo 4 (15 pacientes, formado por casos com história de intolerância à aspirina associado à asma quase fatal. CONCLUSÕES: Um número significativo de portadores de ama grave não adere ao tratamento. Muitos pacientes com asma grave têm obstrução irreversível, mas o fenótipo clínico mais relevante é constituído pelos pacientes resistentes ao tratamento habitual.OBJECTIVE: To characterize clinical phenotypes of severe asthma. METHODS: A total of 111 patients were retrospectively evaluated at a

  6. ¿QUÉ ESCRIBEN LOS ESTUDIANTES DE POSGRADO? TIPOS DE TEXTOS SOLICITADOS EN SEMINARIOS

    Directory of Open Access Journals (Sweden)

    Laura Colombo

    2013-12-01

    Full Text Available El tema "tipos de textos solicitados a los alumnos en sus carreras universitarias" ha sido objeto de varias investigaciones, pero pocas se han centrado en el nivel de posgrado. En este trabajo, mediante una encuesta hecha a 118 participantes, indagamos el punto de vista de los estudiantes de maestrías y doctorados en diversas disciplinas. Los resultados muestran que existen diferencias entre programas de las facultades de artes, humanidades y ciencias sociales; ingeniería y tecnología de la información, y ciencias naturales y matemáticas. A excepción del abstract o resumen, los textos frecuentemente solicitados divergen de aquellos que se escribirán una vez finalizados los estudios. Resalta la poca frecuencia con que se piden artículos para revistas científicas (principal tipo de escrito que se utiliza en todas las disciplinas. Estudios como el aquí propuesto pueden impulsar futuras investigaciones sobre los programas de posgrado y su articulación con el ámbito profesional o académico.

  7. Neurofibromatosis tipo 2: La historia de Lidia Neurofibromatosis type 2: Life story of Lidia

    Directory of Open Access Journals (Sweden)

    Ares Solanes

    2012-06-01

    Full Text Available La Neurofibromatosis tipo 2 (NF2 es una enfermedad minoritaria hereditaria caracterizada por la presentación progresiva de múltiples tumores, especialmente Schwanomas Vestibulares Bilaterales, a partir de la segunda década de vida. Su tratamiento con cirugía o radioterapia no evita la pérdida de audición. El pronóstico es complicado y los pacientes deben enfrentarse al progresivo deterioro de su calidad de vida. Un estudio cualitativo a través de la historia de vida de nuestra informante clave nos permite explorar y comprender su vivencia, afecta de Neurofibromatosis tipo II (NF2, así como conocer sus necesidades y aprender de sus recursos adaptativos.Neurofibromatosis type 2 (NF2 is a minority hereditary disease characterized by the development of multiple tumours, especially bilateral vestibular schwannomas, in young adults. Treatments with surgery or radiotherapy are performed to delay hearing loss. The prognosis is complicated and patients face the deterioration of their quality of life. A qualitative study through our key subject's life allows us to explore and understand her experience, as a NF2 sufferer, to identify her needs and to learn about her adaptive measures.

  8. Los “Panzudos” Arcaicos Griegos: observaciones sobre un curioso tipo iconográfico

    Directory of Open Access Journals (Sweden)

    Arjona Pérez, Manuel

    2013-12-01

    Full Text Available In the 6th century BC, the vascular and cloroplastic workshops of Ancient reproduced, both on plastic vases and terracota figurines, an iconographic type depicting a peculiar nude and smiling fat-bellied male character. This paper deals with aspects related to the variants of this iconographic type, its distribution, the identification of the represented figure, its probable forerunners, as well as the context of the deposition or consecration of its representations.En el siglo VI a.C. los talleres vasculares y coroplásticos helenos reprodujeron, bien sobre vasos plásticos, bien sobre figuritas de terracota, un tipo iconográfico que representa a un curioso personaje masculino que, desnudo y sonriente, luce un vientre prominente. En este artículo tratamos algunas cuestiones relativas a las variaciones de este tipo iconográfico, la amplia difusión del mismo, la identificación del personaje retratado, sus posibles antecedentes y el contexto de la deposición o consagración de sus representaciones.

  9. Tipos de fraudes en carnes y productos cárnicos: una revisión

    Directory of Open Access Journals (Sweden)

    T. Espinoza

    2015-01-01

    Full Text Available En años recientes la importancia del control de alimentos, en cuanto a la identificación de sus componentes para evitar fraudes, ha crecido tanto en interés en las organizaciones estatales como en las empresas y en las industrias. La globalización, el aumento de las importaciones y exportaciones, y los tratados de libre comercio han propiciado un mayor intercambio y acceso de los alimentos a nivel mundial; junto con ello los problemas asociados a los fraudes tales como la adulteración, sustitución, la intencionalidad, y falsificación se han incrementado. Por ello, se han reportado varios trabajos asociados al fraude alimentario, donde en la mayoría de ellas se muestran aplicaciones de nuevas técnicas de identificación. Sin embargo, una discusión acerca de los tipos de fraude y su impacto sobre la sociedad, el bioterrorismo y la religión, ha sido poco abordada. Esta revisión se enfoca básicamente en describir los tipos de fraude en alimentos más comunes. Así como, se mencionan las recientes técnicas disponibles para detectar una adulteración en carnes.

  10. Tipos de tiempo para el turismo de sol y playa en el litoral alicantino

    Directory of Open Access Journals (Sweden)

    Martínez Ibarra, Emilio

    2008-06-01

    Full Text Available In this article the author proposes a series of weather types, with the purpose of evaluating the climatic-tourist potencial for the tourism of sun and beach in the coast of Alicante. The method, analysis of the frequency of the density of use of the practice the suntan and swin, the type of consulted source (webcam images, as well as the diversity of distinguished types, make of this work a novel contribution, in a branch of the knowledge relatively little cultivated although emergent: the Tourist Climatology.

    En el presente trabajo se proponen una serie de tipos de tiempo, con la finalidad de evaluar el potencial climático-turístico para el turismo de sol y playa en el litoral alicantino. El método, análisis de la frecuentación de la densidad de uso de la práctica del bronceado y baño, el medio a partir del cual se ha obtenido la información (imágenes webcam, así como la diversidad de tipos distinguidos, hacen de este trabajo una aportación novedosa, en una rama del conocimiento relativamente poco cultivada aunque emergente: la Climatología Turística.

  11. Opciones tipo barrera sobre la tasa de cambio Peso/Dólar

    Directory of Open Access Journals (Sweden)

    Ángela María Pérez Muñoz

    2007-12-01

    Full Text Available Este artículo es derivado de la investigación titulada Opciones tipo barrera sobretasa de cambio. Se realizó un examen de diversas metodologías existentes parala valoración y medición de los riesgos de las opciones tipo barrera europeas. Larevisión se centró, principalmente, en los métodos numéricos. Las SimulacionesMontecarlo constituyen una metodología para valorar y calcular las coberturas deopciones que dependen de la ruta seguida por los precios del activo subyacentedurante su vida útil. Los resultados generados corroboran que ellas convergensatisfactoriamente en la formulación analítica cuando ésta se ajusta a unaobservación discreta de los precios del activo subyacente. Tales resultados seajustan más cuando se aplica el Método de Control de Varianza de Variables Antitéticas a las Simulaciones Montecarlo. 

  12. Reação de genótipos de soja ao crestamento foliar de cercospora

    Directory of Open Access Journals (Sweden)

    Angela Sathiko Kudo

    2011-01-01

    Full Text Available Foram realizados dois experimentos em um delineamento em blocos ao acaso com três repetições, em Cristalina (GO, na safra de 2005/2006, para avaliar a reação de genótipos de soja convencional e transgênica (RR ao crestamento foliar causado por Cercospora kikuchii. No experimento 1, foram avaliados 86 genótipos de soja convencional e no experimento 2, 30 genótipos de soja convencional e transgênica quanto à reação ao crestamento foliar. Como padrões de genótipos convencionais foram usados Emgopa 313 e Msoy 8001 e como genótipos transgênicos Msoy 8585 RR e Msoy 8787 RR. Os genótipos com menor incidência (<1% da doença no experimento 1 foram: GT04-7229, GT04-8987, GT04-8902, GT04-7991, GT04-8218, GT04-9501, GT04-7020, GT04-7505 e GT04-7439. No experimento 2, os menos afetados foram: GT04-7437 RR, GT04-9192 RR, GT04-8091 RR, GT04-8203, GT04-9265 RR e GT04-9085 RR. Não houve diferença na intensidade de doença entre genótipos transgênicos e convencionais. A intensidade do crestamento nos experimentos foi baixa (área foliar lesionada de 0 a 1,5% e incidência de 0 a 20%.

  13. Supramolecular organotin(IV) dithiocarboxylates as potential antimicrobial agents

    NARCIS (Netherlands)

    Zia-ur-Rehman, [No Value; Muhammady, Niaz; Shah, Afzal; Ali, Saqib; Butler, Ian S.; Meetsma, Auke

    2012-01-01

    A series of tri-, chlorodi-, and diorganotin(IV) derivatives of 4-(2-methoxyphenyl) piperazine-1-carbodithioate (L) {R = n-C4H9 (1), C6H11 (2), CH3 (3) and C6H5 (4)}, (n-C4H9)(2)SnClL (5) and R2SnL2 {R = n-C4H9 (6), C2H5 (7), CH3 (8)} have been synthesized by refluxing organotin(IV) chlorides with t

  14. Why IV Setup for Stream Ciphers is Difficult

    DEFF Research Database (Denmark)

    Zenner, Erik

    2007-01-01

    In recent years, the initialization vector (IV) setup has proven to be the most vulnerable point when designing secure stream ciphers. In this paper, we take a look at possible reasons why this is the case, identifying numerous open research problems in cryptography.......In recent years, the initialization vector (IV) setup has proven to be the most vulnerable point when designing secure stream ciphers. In this paper, we take a look at possible reasons why this is the case, identifying numerous open research problems in cryptography....

  15. Driver for solar cell i-v characteristic plots

    Energy Technology Data Exchange (ETDEWEB)

    Turner, G.B.

    1980-01-15

    A bipolar voltage ramp generator applies a linear voltage through a resistor to a solar cell for plotting its current versus voltage (I-v) characteristic between short circuit and open circuit conditions, with automatic stops at the end points. The resistor serves the multiple purpose of providing a current sensing resistor, setting the full-scale current value, and providing a load line with a slope approximately equal to one, such that it will pass through the origin and the approximate center of the i-v curve with about equal distance from that center to each of the end points.

  16. (Benzyl phenyl sulfoxide-κO)dichloridodiphenyl­tin(IV)

    OpenAIRE

    Guo-Xia Tan; Chang-Fa Zhang; Xi-Cheng Liu

    2011-01-01

    The SnIV atom in the title compound, [Sn(C6H5)2Cl2(C13H12OS)], displays a distorted C2Cl2O trigonal–bipyramidal coordination environment, with a mean Sn—C distance of 2.121 (9) Å and with Sn—O = 2.331 (2) Å. The SnIV atom is displaced by 0.169 (2) Å from the equatorial C2Cl plane towards the direction of the second axially bonded Cl atom.

  17. Respiratory complications of Ehlers-Danlos syndrome type IV.

    Science.gov (United States)

    Dowton, S B; Pincott, S; Demmer, L

    1996-12-01

    Pulmonary complications are described in a case of Ehlers-Danlos syndrome type IV, established by studies of collagen biosynthesis. At age 20.5 years the patient, who had previously suffered a spontaneous colonic perforation, developed intermittent recurrent hemoptysis and had a spontaneous hemopneumothorax. At presentation, imaging studies revealed multiple scattered cavitary lesions in both lungs. On separate occasions large parenchymal cysts ensued and subsequently regressed. Reviews of other reported patients indicate that pulmonary complications do occur in patients with Ehlers-Danlos syndrome type IV but have not resulted directly in patient mortality.

  18. Electrochemical techniques application in corrosion problems of fossil power plants; Aplicacion de tecnicas electroquimicas en problemas de corrosion en centrales termoelectricas

    Energy Technology Data Exchange (ETDEWEB)

    Cano Castillo, Ulises; Garcia Ochoa, Esteban Miguel; Martinez Villafane, Alberto; Mariaca Rodriguez, Liboria; Malo Tamayo, Jose Maria; Uruchurtu Chavarin, Jorge [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1990-12-31

    Some aspects of the electrochemical techniques employed to evaluate the corrosion at low temperature in fossil power plants are commented, as well as the results obtained with the application of them in three power plants of this type. [Espanol] Se comentan algunos aspectos de tecnicas electroquimicas utilizadas para evaluar la corrosion en baja temperatura en centrales termoelectricas, asi como los resultados de la aplicacion de las mismas en tres centrales de este tipo.

  19. The oxidation of water by cerium(IV) catalysed by nanoparticulate RuO2 on mesoporous silica.

    Science.gov (United States)

    King, Nicola C; Dickinson, Calum; Zhou, Wuzong; Bruce, Duncan W

    2005-03-21

    Mesoporous silicates are prepared by templating on the hexagonal (H1) mesophase of surfactant bipyridine complexes of ruthenium(II) using a true liquid-crystal templating approach. On calcination, the surfactant template is removed except for the central metal ion that is oxidised, forming nanoparticles of RuO2 that deposit within the pores. RuO2 is a known oxidation catalyst and, despite its anhydrous nature in these silicates, is found to be very active in catalyzing the oxidation of water by acidic CeIV.

  20. Interaction of local anesthetics with a peptide encompassing the IV/S4-S5 linker of the Na+ channel.

    Science.gov (United States)

    Fraceto, Leonardo F; Oyama, Sérgio; Nakaie, Clóvis R; Spisni, Alberto; de Paula, Eneida; Pertinhez, Thelma A

    2006-08-20

    The peptide pIV/S4-S5 encompasses the cytoplasmic linker between helices S4-S5 in domain IV of the voltage-gated Na+ channel, residues 1644-1664. The interaction of two local anesthetics (LA), lidocaine and benzocaine, with pIV/S4-S5 has been studied by DOSY, heteronuclear NMR 1H-15N-HSQC spectroscopy and computational methods. DOSY indicates that benzocaine, a neutral ester, exhibits stronger interaction with pIV/S4-S5 than lidocaine, a charged amine-amide. Weighted average chemical shifts, Deltadelta(1H-15N), show that benzocaine affects residues L1653, M1655 and S1656 while lidocaine slightly perturbs residues I1646, L1649 and A1659, L1660, near the N- and C-terminus, respectively. Computational methods confirmed the stability of the benzocaine binding and the existence of two binding sites for lidocaine. Even considering that the approach of studying the peptide in the presence of a co-solvent (TFE/H2O, 30%/70% v/v) has an inherently limited implication, our data strongly support the existence of multiple LA binding sites in the IV/S4-S5 linker, as suggested in the literature. In addition, we consider that LA can bind to the S4-S5 linker with diverse binding modes and strength since this linker is part of the receptor for the "inactivation gate particle". Conditions for devising new functional studies, aiming to better understand Na+ channel functionality as well as the various facets of LA pharmacological activity are proposed in this work.

  1. SDSS-IV MaNGA - the spatially resolved transition from star formation to quiescence

    Science.gov (United States)

    Belfiore, Francesco; Maiolino, Roberto; Maraston, Claudia; Emsellem, Eric; Bershady, Matthew A.; Masters, Karen L.; Bizyaev, Dmitry; Boquien, Médéric; Brownstein, Joel R.; Bundy, Kevin; Diamond-Stanic, Aleksandar M.; Drory, Niv; Heckman, Timothy M.; Law, David R.; Malanushenko, Olena; Oravetz, Audrey; Pan, Kaike; Roman-Lopes, Alexandre; Thomas, Daniel; Weijmans, Anne-Marie; Westfall, Kyle B.; Yan, Renbin

    2017-04-01

    Using spatially resolved spectroscopy from SDSS-IV MaNGA we have demonstrated that low ionization emission-line regions (LIERs) in local galaxies result from photoionization by hot evolved stars, not active galactic nuclei, hence tracing galactic region hosting old stellar population where, despite the presence of ionized gas, star formation is no longer occurring. LIERs are ubiquitous in both quiescent galaxies and in the central regions of galaxies where star formation takes place at larger radii. We refer to these two classes of galaxies as extended LIER (eLIER) and central LIER (cLIER) galaxies, respectively. cLIERs are late-type galaxies primarily spread across the green valley, in the transition region between the star formation main sequence and quiescent galaxies. These galaxies display regular disc rotation in both stars and gas, although featuring a higher central stellar velocity dispersion than star-forming galaxies of the same mass. cLIERs are consistent with being slowly quenched inside-out; the transformation is associated with massive bulges, pointing towards the importance of bulge growth via secular evolution. eLIERs are morphologically early types and are indistinguishable from passive galaxies devoid of line emission in terms of their stellar populations, morphology and central stellar velocity dispersion. Ionized gas in eLIERs shows both disturbed and disc-like kinematics. When a large-scale flow/rotation is observed in the gas, it is often misaligned relative to the stellar component. These features indicate that eLIERs are passive galaxies harbouring a residual cold gas component, acquired mostly via external accretion. Importantly, quiescent galaxies devoid of line emission reside in denser environments and have significantly higher satellite fraction than eLIERs. Environmental effects thus represent the likely cause for the existence of line-less galaxies on the red sequence.

  2. Influência da temperatura sobre os tipos celulares presentes na hemolinfa de larvas e ninfas de Rhipicephalus sanguineus

    Directory of Open Access Journals (Sweden)

    Carneiro M.E.

    2003-01-01

    Full Text Available Este trabalho foi realizado com o intuito de se verificar a influência de três temperaturas (18, 27 e 32°C sobre os tipos celulares presentes na hemolinfa de larvas e ninfas de Rhipicephalus sanguineus (Latreille, 1806. Seis tipos celulares básicos foram encontrados na hemolinfa: prohemócitos (PR, plasmatócitos (PL, granulócitos (GR, esferulócitos (ES, adipohemócitos (AD e oenocitóides (OE. Os ES foram divididos em dois subtipos (ES I e ES II, devido às variações morfológicas encontradas. O efeito da temperatura foi mais acentuado sobre o estádio de larva. Ocorreu queda acentuada de GR e aumento de ES II na temperatura de 18°C, enquanto que à 27 e 32°C, os valores foram semelhantes. GR foi o tipo celular mais abundante, indicando o seu envolvimento no metabolismo. Para ninfas este também foi o tipo celular mais abundante, porém não ocorreram variações acentuadas segundo a temperatura, indicando que cada estádio de desenvolvimento apresenta determinada necessidade metabólica que se expressa nos tipos celulares presentes na hemolinfa.

  3. Efecto de los factores socioculturales en la capacidad de autocuidado del paciente hospitalizado con diabetes tipo 2

    Directory of Open Access Journals (Sweden)

    Mireya Gricelia Galindo-Martínez

    2014-01-01

    Full Text Available Introducción: la diabetes tipo 2 es considerada como un problema de salud pública por su creciente prevalencia e incidencia. Obje- tivo: describir el efecto de los factores socioculturales en la capacidad de autocuidado del paciente hospitalizado con diabetes tipo 2 en el Hospital General de Tecomán, Colima, México. Método: estudio transversal, observacional. Se trabajó con 68 pacientes hospitalizados con diabetes tipo 2; se utilizó un instrumento que midió el efecto de los factores socioculturales en la capacidad de autocuidado. El análisis de datos se realizó con Razón de Momios, intervalos de confianza al 95 % y fracción atribuible en expuestos. Resultados: los factores socioculturales tuvieron un leve efecto positivo en la capacidad de autocuidado (RM = 1,10; IC 95 %: 0,26-4,74 en pacientes hospitali- zados con diabetes tipo 2. Conclusiones: los factores socioculturales: experiencias vitales, experiencias laborales, religión, costumbres y tradiciones, prácticas curativas y ritos, señalados en la Teoría General del Déficit de Autocuidado, muestran un efecto positivo sobre la capacidad de autocuidado de las personas con diabetes tipo 2.

  4. Bionic self-sufficient greenhouses and cattle breeding. Agrosphere IV; Bionisch autarkische glastuinbouw en veeteelt. Agrosphere IV

    Energy Technology Data Exchange (ETDEWEB)

    Schmitz, A.H.H. [VERWOL Klimaatplafonds, Delft (Netherlands)

    2007-09-15

    Agrosphere-IV is a concept in which cattle breeding and greenhouse culture are combined in an artificial cycle which functions similar to the cycles on earth. In this article attention is paid to the combination of greenhouses for the production of paprikas (peppers) or tomatoes and breeding of pigs (porkers) [Dutch] Met de ontwikkeling van Agrosphere-IV is een vierde biosfeerconcept benoemd. Waar huidige agroconcepten nog uitgaan van samenvoeging van traditionele veeteelt- en glastuinbouwconcepten betreft het hier een directe koppeling van veeteelt en glastuinbouw. De koppeling heeft plaats via uitgekiende luchtstromen en hergebruik van de afvalstromen en vormt zo een bionisch autarkisch systeem.

  5. Viabilidade de uso do delineamento composto central

    Directory of Open Access Journals (Sweden)

    Nazaré Barata Mateus

    2001-05-01

    Full Text Available O delineamento composto central é um delineamento simétrico e de segunda ordem, constituído de duas partes: o fatorial 2k, com um ou mais pontos centrais, e a parte axial. O objetivo deste trabalho foi o de verificar, com simulações, a viabilidade do uso desse tipo de delineamento nas áreas de pesquisas de campo, como em Agronomia; em laboratórios de Fitopatologia, Virologia e Entomologia, em pesquisas onde o coeficiente de variação não é superior a 6%; e na indústria química, com coeficiente de variação abaixo de 3%. Através das simulações, verificou-se que seu uso não é conveniente em áreas de pesquisa, cujo coeficiente de variação seja superior a 6%, quando se buscam estimativas de resposta e dos pontos ótimos e também em pesquisas de campo, como na Agronomia, mesmo quando se repetem todos os tratamentos, pois se observam muitas respostas e pontos bem longe do esperado

  6. CENTRAL PLATEAU REMEDIATION

    Energy Technology Data Exchange (ETDEWEB)

    ROMINE, L.D.

    2006-02-01

    A systematic approach to closure planning is being implemented at the Hanford Site's Central Plateau to help achieve the goal of closure by the year 2035. The overall objective of Central Plateau remediation is to protect human health and the environment from the significant quantity of contaminated material that resulted from decades of plutonium production in support of the nation's defense. This goal will be achieved either by removing contaminants or placing the residual contaminated materials in a secure configuration that minimizes further migration to the groundwater and reduces the potential for inadvertent intrusion into contaminated sites. The approach to Central Plateau cleanup used three key concepts--closure zones, closure elements, and closure process steps--to create an organized picture of actions required to complete remediation. These actions were merged with logic ties, constraints, and required resources to produce an integrated time-phased schedule and cost profile for Central Plateau closure. Programmatic risks associated with implementation of Central Plateau closure were identified and analyzed. Actions to mitigate the most significant risks are underway while high priority remediation projects continue to make progress.

  7. Solar Neutrino Measurements in Super-Kamiokande-IV

    CERN Document Server

    :,; Haga, Y; Hayato, Y; Ikeda, M; Iyogi, K; Kameda, J; Kishimoto, Y; Marti, Ll; Miura, M; Moriyama, S; Nakahata, M; Nakajima, T; Nakayama, S; Orii, A; Sekiya, H; Shiozawa, M; Sonoda, Y; Takeda, A; Tanaka, H; Takenaga, Y; Tasaka, S; Tomura, T; Ueno, K; Yokozawa, T; Akutsu, R; Irvine, T; Kaji, H; Kajita, T; Kametani, I; Kaneyuki, K; Lee, K P; Nishimura, Y; McLachlan, T; Okumura, K; Richard, E; Labarga, L; Fernandez, P; Blaszczyk, F d M; Gustafson, J; Kachulis, C; Kearns, E; Raaf, 32 J L; Stone, J L; Sulak, 32 L R; Berkman, S; Tobayama, S; Goldhaber, M; Bays, K; Carminati, G; Griskevich, N J; Kropp, W R; Mine, S; Renshaw, A; Smy, M B; Sobel, H W; Takhistov, V; Weatherly, P; Ganezer, K S; Hartfiel, B L; Hill, J; Keig, W E; Hong, N; Kim, J Y; Lim, I T; Park, R G; Akiri, T; Albert, J B; Himmel, A; Li, Z; O'Sullivan, E; Scholberg, K; Walter, C W; Wongjirad, T; Ishizuka, T; Nakamura, T; Jang, J S; Choi, K; Learned, J G; Matsuno, S; Smith, S N; Friend, M; Hasegawa, T; Ishida, T; Ishii, T; Kobayashi, T; Nakadaira, T; Nakamura, K; Nishikawa, K; Oyama, Y; Sakashita, K; Sekiguchi, T; Tsukamoto, T; Nakano, Y; Suzuki, A T; Takeuchi, Y; Yano, T; Cao, S V; Hayashino, T; Hiraki, T; Hirota, S; Huang, K; Ieki, K; Jiang, M; Kikawa, T; Minamino, A; Murakami, A; Nakaya, T; Patel, N D; Suzuki, K; Takahashi, S; Wendell, R A; Fukuda, Y; Itow, Y; Mitsuka, G; Muto, F; Suzuki, T; Mijakowski, P; Frankiewicz, K; Hignight, J; Imber, J; Jung, C K; Li, X; Palomino, J L; Santucci, G; Taylor, I; Vilela, C; Wilking, M J; Yanagisawa, C; Fukuda, D; Ishino, H; Kayano, T; Kibayashi, A; Koshio, Y; Mori, T; Sakuda, M; Takeuchi, J; Yamaguchi, R; Kuno, Y; Tacik, R; Kim, S B; Okazawa, H; Choi, Y; Ito, K; Nishijima, K; Koshiba, M; Totsuka, Y; Suda, Y; Yokoyama, M; Nantais, C M; Martin, J F; de Perio, P; Tanaka, H A; Konaka, A; Chen, S; Sui, H; Wan, L; Yang, Z; Zhang, H; Zhang, Y; Connolly, K; Dziomba, M; Wilkes, R J

    2016-01-01

    Upgraded electronics, improved water system dynamics, better calibration and analysis techniques allowed Super-Kamiokande-IV to clearly observe very low-energy 8B solar neutrino interactions, with recoil electron kinetic energies as low as 3.49 MeV. Super-Kamiokande-IV data-taking began in September of 2008; this paper includes data until February 2014, a total livetime of 1664 days. The measured solar neutrino flux is (2.308+-0.020(stat.) + 0.039-0.040(syst.)) x 106/(cm2sec) assuming no oscillations. The observed recoil electron energy spectrum is consistent with no distortions due to neutrino oscillations. An extended maximum likelihood fit to the amplitude of the expected solar zenith angle variation of the neutrino-electron elastic scattering rate in SK-IV results in a day/night asymmetry of (-3.6+-1.6(stat.)+-0.6(syst.))%. The SK-IV solar neutrino data determine the solar mixing angle as sin2 theta_12 = 0.327+0.026-0.031, all SK solar data (SK-I, SK-II, SK III and SKIV) measures this angle to be sin2 the...

  8. Lamstatin - a novel inhibitor of lymphangiogenesis derived from collagen IV

    NARCIS (Netherlands)

    Weckmann, Markus; Moir, Lyn Margaret; Heckman, Caroline Akemi; Black, Judith Lee; Oliver, Brian Gregory; Burgess, Janette Kay

    2012-01-01

    The lymphatic system is essential for the maintenance of tissue homeostasis and immunity. Its dysfunction in disease (such as lymphangioleiomyomatosis) can lead to chylous effusions, oedema or dissemination of malignant cells. Collagen IV has six a chains, of which some of the non-collagenous-1 doma

  9. 76 FR 36095 - Defense Transportation Regulation, Part IV

    Science.gov (United States)

    2011-06-21

    ... ID: DOD-2010- OS-0034, published April 1, 2010 (75 FR 16445-16446). DOD has completed their review... III Domestic Small Shipments (dS2) and Nontemporary Storage (NTS) draft business rules. Responses can.../part-iv/phaseiii.cfm . All identified changes have been incorporated into the final dS2 and...

  10. 顶级体验 NIKE TIEMPO LEGEND IV ELITE

    Institute of Scientific and Technical Information of China (English)

    Sexxxxxy

    2011-01-01

    NIKE(耐克)在7月1日推出了LEGEND系列的最新战靴TIEMPO LEGEND IV ELITE,这款首创了真皮加飞线鞋面的足球鞋拥有怎样的性能表现,一直是我们非常想了解的。

  11. 25 CFR 36.13 - Standard IV-Curriculum development.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Standard IV-Curriculum development. 36.13 Section 36.13... § 36.13 Standard IV—Curriculum development. (a) Each school shall implement an organized program of curriculum development involving certified and non-certified staff and shall provide the opportunity...

  12. WAIS-IV Subtest Covariance Structure: Conceptual and Statistical Considerations

    Science.gov (United States)

    Ward, L. Charles; Bergman, Maria A.; Hebert, Katina R.

    2012-01-01

    D. Wechsler (2008b) reported confirmatory factor analyses (CFAs) with standardization data (ages 16-69 years) for 10 core and 5 supplemental subtests from the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV). Analyses of the 15 subtests supported 4 hypothesized oblique factors (Verbal Comprehension, Working Memory, Perceptual Reasoning,…

  13. Discrepancy Score Reliabilities in the WAIS-IV Standardization Sample

    Science.gov (United States)

    Glass, Laura A.; Ryan, Joseph J.; Charter, Richard A.

    2010-01-01

    In the present investigation, the authors provide internal consistency reliabilities for Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) subtest and Index discrepancy scores using the standardization sample as the data source. Reliabilities ranged from 0.55 to 0.88 for subtest discrepancy scores and 0.80 to 0.91 for Index discrepancy…

  14. WAIS-IV profile of cognition in schizophrenia.

    Science.gov (United States)

    Michel, Natalie M; Goldberg, Joel O; Heinrichs, R Walter; Miles, Ashley A; Ammari, Narmeen; McDermid Vaz, Stephanie

    2013-08-01

    The Wechsler Adult Intelligence Scale (WAIS) has been used extensively to study impairment across a range of cognitive domains in schizophrenia. However, cognitive performance among those with the illness has yet to be examined using the newest edition of this measure. Hence, the current study aims first, to provide WAIS-IV normative data for Canadian individuals with schizophrenia of low average intelligence; second, to examine schizophrenia performance on all WAIS-IV subtest, index and general intelligence scores relative to healthy comparison subjects; and third, to revalidate the pattern of impairment identified in this clinical group using the WAIS-III, where processing speed (PS) was most affected, followed by working memory (WM), perceptual reasoning (PR) and verbal comprehension (VC). The WAIS-IV was administered to outpatients with schizophrenia and their performance compared with age, gender, and education matched controls. WAIS-IV schizophrenia performance data are provided. Analyses revealed significant impairment on several tasks, including the new Cancellation subtest and the VC supplemental subtest, Comprehension. At the index score level, group differences in PS were significantly larger than those observed in all other cognitive domains. Impairments were also observed in WM amid relatively preserved performance in VC, thereby confirming the pattern of impairment identified using the WAIS-III.

  15. Tetrakis(bis(trimethylsilyl)amido)uranium(IV): synthesis and reactivity.

    Science.gov (United States)

    Lewis, Andrew J; Williams, Ursula J; Carroll, Patrick J; Schelter, Eric J

    2013-07-01

    The synthesis of the sterically saturated uranium(IV) complex U[N(SiMe3)2]4 (1) is demonstrated from the one-electron oxidation of U[N(SiMe3)2]3 with a variety of oxidants in THF. A high yielding synthesis of 1 directly from UI3(THF)4 is provided.

  16. Archaeal type IV pili and their involvement in biofilm formation.

    Science.gov (United States)

    Pohlschroder, Mechthild; Esquivel, Rianne N

    2015-01-01

    Type IV pili are ancient proteinaceous structures present on the cell surface of species in nearly all bacterial and archaeal phyla. These filaments, which are required for a diverse array of important cellular processes, are assembled employing a conserved set of core components. While type IV pilins, the structural subunits of pili, share little sequence homology, their signal peptides are structurally conserved allowing for in silico prediction. Recently, in vivo studies in model archaea representing the euryarchaeal and crenarchaeal kingdoms confirmed that several of these pilins are incorporated into type IV adhesion pili. In addition to facilitating surface adhesion, these in vivo studies also showed that several predicted pilins are required for additional functions that are critical to biofilm formation. Examples include the subunits of Sulfolobus acidocaldarius Ups pili, which are induced by exposure to UV light and promote cell aggregation and conjugation, and a subset of the Haloferax volcanii adhesion pilins, which play a critical role in microcolony formation while other pilins inhibit this process. The recent discovery of novel pilin functions such as the ability of haloarchaeal adhesion pilins to regulate swimming motility may point to novel regulatory pathways conserved across prokaryotic domains. In this review, we will discuss recent advances in our understanding of the functional roles played by archaeal type IV adhesion pili and their subunits, with particular emphasis on their involvement in biofilm formation.

  17. Nascent transcription affected by RNA polymerase IV in Zea mays.

    Science.gov (United States)

    Erhard, Karl F; Talbot, Joy-El R B; Deans, Natalie C; McClish, Allison E; Hollick, Jay B

    2015-04-01

    All eukaryotes use three DNA-dependent RNA polymerases (RNAPs) to create cellular RNAs from DNA templates. Plants have additional RNAPs related to Pol II, but their evolutionary role(s) remain largely unknown. Zea mays (maize) RNA polymerase D1 (RPD1), the largest subunit of RNA polymerase IV (Pol IV), is required for normal plant development, paramutation, transcriptional repression of certain transposable elements (TEs), and transcriptional regulation of specific alleles. Here, we define the nascent transcriptomes of rpd1 mutant and wild-type (WT) seedlings using global run-on sequencing (GRO-seq) to identify the broader targets of RPD1-based regulation. Comparisons of WT and rpd1 mutant GRO-seq profiles indicate that Pol IV globally affects transcription at both transcriptional start sites and immediately downstream of polyadenylation addition sites. We found no evidence of divergent transcription from gene promoters as seen in mammalian GRO-seq profiles. Statistical comparisons identify genes and TEs whose transcription is affected by RPD1. Most examples of significant increases in genic antisense transcription appear to be initiated by 3'-proximal long terminal repeat retrotransposons. These results indicate that maize Pol IV specifies Pol II-based transcriptional regulation for specific regions of the maize genome including genes having developmental significance.

  18. 76 FR 31327 - Draft National Coastal Condition Report IV

    Science.gov (United States)

    2011-05-31

    ... Oceanic and Atmospheric Administration (NOAA) and the U.S. Fish and Wildlife Services (USFWS), and coastal... conterminous U.S., Alaska, Hawaii, and Puerto Rico. The NCCR IV data were collected from 3,144 sites from 2003... West Coast) and comparisons of these waters with near-shore condition, trends in regional...

  19. Transient C IV Broad Absorption Lines in radio detected QSOs

    CERN Document Server

    Vivek, M; Gupta, N

    2015-01-01

    We study the transient (i.e. emerging or disappearing) C IV broad absorption line (BAL) components in 50 radio detected QSOs using multi-epoch spectra available in Sloan Digital Sky Survey DR10. We report the detectionof 6 BALQSOs having at least one distinct transient C IV absorption component. Based on the structure function analysis of optical light curves, we suggest that the transient absorption is unlikely to be triggered by continuum variations. Transient absorption components usually have low C IV equivalent widths ( 10000 \\kms) and typically occur over rest-frame timescales > 800 days. The detection rate of transient C IV absorption seen in our sample is higher than that reported in the literature. Using a control sample of QSOs, we show that this difference is most likely due to the longer monitoring time-scale of sources in our sample while the effect of small number statistics cannot be ignored. Thus, in order to establish the role played by radio jets in driving the BAL outflows, we need a larger...

  20. Rhenium(IV) compounds inducing apoptosis in cancer cells.

    Science.gov (United States)

    Martínez-Lillo, José; Mastropietro, Teresa F; Lappano, Rosamaria; Madeo, Antonio; Alberto, Marta E; Russo, Nino; Maggiolini, Marcello; De Munno, Giovanni

    2011-05-14

    The anticancer properties of a series of mononuclear Re(IV) compounds of formula ReCl(4)L (where L is bpy = 2,2'-bipyridine; bpym = 2,2'-bipyrimidine; dmbpy = 4,4'-dimethyl-2,2'-bipyridine; phen = 1,10-phenanthroline) were investigated for the first time. All compounds displayed potent in vitro antiproliferative activity against selected cancer cells.