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Sample records for central nucleus icc

  1. Centrality Dependence of Flow in High-Energy Nucleus-Nucleus Collisions

    Institute of Scientific and Technical Information of China (English)

    杨红艳; 周代翠; 杨纯斌; 蔡勖

    2002-01-01

    Directed flow and elliptic flow of final state particles in high-energy nucleus-nucleus collisions in the EMU01 experiment have been studied. The dependences of directed flow and elliptic flow on incident energy and impact centrality of outgoing particles are presented. The results exhibit strong dependence of flow on centrality and energy. We also suggest a more reliable way to determine the event plane resolution here.

  2. ICCS 2009 Technical Report

    Science.gov (United States)

    Schulz, Wolfram, Ed.; Ainley, John, Ed.; Fraillon, Julian, Ed.

    2011-01-01

    This report is structured so as to provide technical detail about each aspect of International Civic and Citizenship Education Study (ICCS). The overview is followed by a series of chapters that provide detail about different aspects of ICCS. Chapters, 2, 3, 4, and 5 are concerned with the instruments. Chapter 2 provides information about the…

  3. ICCS for DC applications

    International Nuclear Information System (INIS)

    Superconducting magnet windings in which AC heating is insignificant can benefit from the elimination of transient heat transfer limits on stability and also from the use of high strength, moderate conductivity copper and aluminum alloys for thermal ''protection''. The way in which these benefits accrue from the use of ICCS for DC devices is described

  4. Colour of the nucleus as a marker of nuclear hardness, diameter and central thickness

    OpenAIRE

    Gullapalli Vamsi; Murthy Praveen; Murthy K

    1995-01-01

    Hundred and thirty patients, aged above 40 years, with senile cataract were examined. Age and colour were selected as the probable preoperative indicators of nuclear hardness. The lens material collected after manual extracapsular extraction was washed and the nucleus isolated. The diameter and central thickness of the nucleus were measured; the mean diameter and mean central thickness were 7.13 mm ± 0.76 and 3.05 mm ± 0.48, respectively. The hardness of the nucleus was measured...

  5. Consolidation of altered associability information by amygdala central nucleus.

    Science.gov (United States)

    Schiffino, Felipe L; Holland, Peter C

    2016-09-01

    The surprising omission of a reinforcer can enhance the associability of the stimuli that were present when the reward prediction error was induced, so that they more readily enter into new associations in the future. Previous research from this laboratory identified brain circuit elements critical to the enhancement of stimulus associability by the omission of an expected event and to the subsequent expression of that altered associability in more rapid learning. These elements include the amygdala, the midbrain substantia nigra, the basal forebrain substantia innominata, the dorsolateral striatum, the secondary visual cortex, and the posterior parietal cortex. Here, we found that consolidation of a surprise-enhanced associability memory in a serial prediction task depends on processing in the amygdala central nucleus (CeA) after completion of sessions that included the surprising omission of an expected event. Post-surprise infusions of anisomycin, lidocaine, or muscimol prevented subsequent display of surprise-enhanced associability. Because previous studies indicated that CeA function is unnecessary for the expression of associability enhancements that were induced previously when CeA function was intact (Holland & Gallagher, 2006), we interpreted these results as indicating that post-surprise activity of CeA ("surprise replay") is necessary for the consolidation of altered associability memories elsewhere in the brain, such as the posterior parietal cortex (Schiffino et al., 2014a). PMID:27427328

  6. Hacia la mejora del servicio al cliente: Lecciones sobre la creación y consolidación de la Central Única de Atención al Cliente ITE (ICC)

    OpenAIRE

    Banco Interamericano de Desarrollo (BID)

    2009-01-01

    En medio de un cambio institucional de grandes proporciones, el Departamento de Tecnología de la Información (ITE) del BID asumió el reto de mejorar la eficacia y eficiencia de sus servicios informáticos y técnicos, consolidándolos en lo que hoy se conoce como Central Única de Atención al Cliente de ITE (ICC). Esta experiencia ha dejado varias enseñanzas relevantes para el Banco que se comparten en esta nota.

  7. Corticotropin-releasing factor within the central nucleus of the amygdala and the nucleus accumbens shell mediates the negative affective state of nicotine withdrawal in rats

    OpenAIRE

    Marcinkiewcz, Catherine A.; Prado, Melissa M.; Isaac, Shani K.; Marshall, Alex.; Rylkova, Daria; Bruijnzeel, Adrie W.

    2009-01-01

    Tobacco addiction is a chronic disorder that is characterized by a negative affective state upon smoking cessation and relapse after periods of abstinence. Previous research has shown that an increased central release of corticotropin-releasing factor (CRF) at least partly mediates the deficit in brain reward function associated with nicotine withdrawal in rats. The aim of these studies was to investigate the role of CRF in the central nucleus of the amygdala (CeA), the lateral bed nucleus of...

  8. Baroreflex failure in a patient with central nervous system lesions involving the nucleus tractus solitarii

    Science.gov (United States)

    Biaggioni, I.; Whetsell, W. O.; Jobe, J.; Nadeau, J. H.

    1994-01-01

    Animal studies have shown the importance of the nucleus tractus solitarii, a collection of neurons in the brain stem, in the acute regulation of blood pressure. Impulses arising from the carotid and aortic baroreceptors converge in this center, where the first synapse of the baroreflex is located. Stimulation of the nucleus tractus solitarii provides an inhibitory signal to other brain stem structures, particularly the rostral ventrolateral medulla, resulting in a reduction in sympathetic outflow and a decrease in blood pressure. Conversely, experimental lesions of the nucleus tractus solitarii lead to loss of baroreflex control of blood pressure, sympathetic activation, and severe hypertension in animals. In humans, baroreflex failure due to deafferentation of baroreceptors has been previously reported and is characterized by episodes of severe hypertension and tachycardia. We present a patient with an undetermined process of the central nervous system characterized pathologically by ubiquitous infarctions that were particularly prominent in the nucleus tractus solitarii bilaterally but spared the rostral ventrolateral medulla. Absence of a functioning baroreflex was evidenced by the lack of reflex tachycardia to the hypotensive effects of sodium nitroprusside, exaggerated pressor responses to handgrip and cold pressor test, and exaggerated depressor responses to meals and centrally acting alpha 2-agonists. This clinicopathological correlate suggests that the patient's baroreflex failure can be explained by the unique combination of the destruction of sympathetic inhibitory centers (ie, the nucleus tractus solitarii) and preservation of centers that exert a positive modulation on sympathetic tone (ie, the rostral ventrolateral medulla).

  9. Central 56-Fe-nucleus reactions at 1.7 GeV/nucleon

    International Nuclear Information System (INIS)

    Preliminary results on multiplicity and angular distributions in 56Fe-nucleus reactions at 1.7 GeV/nucleon are given. In particular we study central collisions in C, N and O. These reactions show a very characteristic behaviour with all charged particles in the forward hemisphere in the lab system, but with very few particles within the expected projectile fragmentation cone. Furthermore in these reactions a large number of fast protons (p > 1 GeV/c) originate from the target nucleus

  10. Centrality-dependent forward $J/\\psi$ production in high energy proton-nucleus collisions

    CERN Document Server

    Ducloué, B; Mäntysaari, H

    2016-01-01

    Forward $J/\\psi$ production and suppression in high energy proton-nucleus collisions can be an important probe of gluon saturation. In an earlier work we studied this process in the Color Glass Condensate framework and showed that using the Glauber approach to extrapolate the dipole cross section of a proton to a nucleus leads to results closer to experimental data than previous calculations in this framework. Here we investigate the centrality dependence of the nuclear suppression in this model and show a comparison of our results with recent LHC data.

  11. Colour of the nucleus as a marker of nuclear hardness, diameter and central thickness.

    Science.gov (United States)

    Gullapalli, V K; Murthy, P R; Murthy, K R

    1995-12-01

    Hundred and thirty patients, aged above 40 years, with senile cataract were examined. Age and colour were selected as the probable preoperative indicators of nuclear hardness. The lens material collected after manual extracapsular extraction was washed and the nucleus isolated. The diameter and central thickness of the nucleus were measured; the mean diameter and mean central thickness were 7.13 mm +/- 0.76 and 3.05 mm +/- 0.48, respectively. The hardness of the nucleus was measured with a lens guillotine designed by us. Regression analysis was applied to the parameters measured and these were compared with the colour and age. The parameters measured had the following relationship: Colour vs hardness (r value = 0.7569) (p 0.05) Age vs diameter (r value = 0.0987) (p > 0.05) Age vs central thickness (r value = 0.1700) (p > 0.05) The values showed that colour had a statistically significant relationship with all the 3 parameters (p cataractous lens nucleus, the preoperative knowledge of which would help the surgeon in planning small-incision surgery including phacoemulsification. PMID:8655196

  12. FY97 ICCS prototype specification

    International Nuclear Information System (INIS)

    The ICCS software team will implement and test two iterations of their software product during FY97. This document specifies the products to be delivered in that first prototype and projects the direction that the second prototype will take. Detailed specification of the later iteration will be written when the results of the first iteration are complete. The selection of frameworks to be implemented early is made on a basis of risk analysis from the point of view of future development in the ICCS project. The prototype will address risks in integration of object- oriented components, in refining our development process, and in emulation testing for FEP devices. This document is a specification that identifies products and processes to undertake for resolving these risks. The goals of this activity are to exercise our development process at a modest scale and to probe our architecture plan for fundamental limits and failure modes. The product of the iterations will be the framework software which will be useful in future ICCS code. Thus the FY97 products are intended for internal usage by the ICCS team and for demonstration to the FEP software developers of the strategy for integrating supervisory software with FEP computers. This will be the first of several expected iterations of the software development process and the performance measurements that ICCS will demonstrate, intended to support confidence in our ability to meet project RAM goals. The design of the application software is being carried out in a separate WBS 1.5.2 activity. The design activity has as its FY97 product a series of Software Design Documents that will specify the functionality of the controls software of ICCS. During the testing of this year''s prototypes, the application functionality needed for test will be provided by sample maintenance controls. These are early precursors of controls that can be used for low level device control. Since the devices under test will be represented by

  13. Central and peripheral contributions to dynamic changes in nucleus accumbens glucose induced by intravenous cocaine

    OpenAIRE

    Wakabayashi, Ken T.; Kiyatkin, Eugene A

    2015-01-01

    The pattern of neural, physiological and behavioral effects induced by cocaine is consistent with metabolic neural activation, yet direct attempts to evaluate central metabolic effects of this drug have produced controversial results. Here, we used enzyme-based glucose sensors coupled with high-speed amperometry in freely moving rats to examine how intravenous cocaine at a behaviorally active dose affects extracellular glucose levels in the nucleus accumbens (NAc), a critical structure within...

  14. Colour of the nucleus as a marker of nuclear hardness, diameter and central thickness

    Directory of Open Access Journals (Sweden)

    Gullapalli Vamsi

    1995-01-01

    Full Text Available Hundred and thirty patients, aged above 40 years, with senile cataract were examined. Age and colour were selected as the probable preoperative indicators of nuclear hardness. The lens material collected after manual extracapsular extraction was washed and the nucleus isolated. The diameter and central thickness of the nucleus were measured; the mean diameter and mean central thickness were 7.13 mm ± 0.76 and 3.05 mm ± 0.48, respectively. The hardness of the nucleus was measured with a lens guillotine designed by us. Regression analysis was applied to the parameters measured and these were compared with the colour and age. The parameters measured had the following relationship: Colour vs hardness (r value = 0.7569 (p < 0.001 Colour vs diameter (r value = 0.3962 (p < 0.001 Colour vs central thickness (r value = 0.4785 (p < 0.001 Age vs hardness (r value = -0.0499 (p > 0.05 Age vs diameter (r value = 0.0987 (p > 0.05 Age vs central thickness (r value = 0.1700 (p > 0.05 The values showed that colour had a statistically significant relationship with all the 3 parameters (p < 0.001, while age had no significant relationship with the same parameters. The results indicated that colour can be used more reliably to predict physical characteristics of the cataractous lens nucleus, the preoperative knowledge of which would help the surgeon in planning small-incision surgery including phacoemulsification.

  15. A hybrid set-up to study charmed particle production in {sup 32}S-nucleus central interactions

    Energy Technology Data Exchange (ETDEWEB)

    Armenise, N. [Dipartimento di Fisica dell`Universita and INFN, Bari (Italy); Beker, H. [European Organization for Nuclear Research, Geneva (Switzerland); Bisi, V. [Dipartimento di Fisica Sperimentale dell`Universita and INFN, Turin (Italy)] [and others; EMU09 Collaboration

    1995-07-15

    An emulsion-counter hybrid set-up to detect charmed particle decays in samples of triggered {sup 32}S-nucleus central interactions is described. A new tracking technique with two emulsion tapes was developed and used successfully. (orig.).

  16. A hybrid set-up to study charmed particle production in 32S-nucleus central interactions

    International Nuclear Information System (INIS)

    An emulsion-counter hybrid set-up to detect charmed particle decays in samples of triggered 32S-nucleus central interactions is described. A new tracking technique with two emulsion tapes was developed and used successfully. (orig.)

  17. Current ideas on central chemoreception by neurons and glial cells in the retrotrapezoid nucleus

    OpenAIRE

    Mulkey, Daniel K.; Wenker, Ian C.; Kréneisz, Orsolya

    2010-01-01

    Central chemoreception is the mechanism by which CO2/pH-sensitive neurons (i.e., chemoreceptors) regulate breathing in response to changes in tissue pH. A region of the brain stem called the retrotrapezoid nucleus (RTN) is thought to be an important site of chemoreception (23), and recent evidence suggests that RTN chemoreception involves two interrelated mechanisms: H+-mediated activation of pH-sensitive neurons (38) and purinergic signaling (19), possibly from pH-sensitive glial cells. A th...

  18. Stability of Ionic Colloidal Crystals (ICCs)

    Science.gov (United States)

    Maskaly, Garry R.; Garcia, R. Edwin; Carter, W. Craig; Chiang, Yet-Ming

    2003-03-01

    Ionic colloidal crystals (ICCs) are here defined as ordered multicomponent colloids formed by attractive electrostatic interactions. Compared to previous approaches to colloidal crystallization, the ICC approach holds the potential for self-assembly of a wide range of structures not easily accessible by other methods. In this work, the colloid-chemical conditions under which ICCs are stable have been theoretically analyzed. A model is presented in which two dimensionless parameters are found to fully characterize an ICC system. We calculate the Madelung constant for ICCs of several classical ionic crystal structures as a function of these two parameters, and discuss the parallels between the ICC Madelung constants and the classical ionic case. Experimentally accessible regions of surface charge, particle sizes, salt concentration, and temperature where ionic colloidal crystallization should be possible are identified.

  19. Synthesis of Ionic Colloidal Crystals (ICCs)

    Science.gov (United States)

    Maskaly, Garry R.; Garcia, R. Edwin; Carter, W. Craig; Chiang, Yet-Ming

    2003-03-01

    Binary ionic colloidal crystals (ICCs) have been produced by ordered heterocoagulation of colloidal mixtures of silica (negative surface charge) and polystyrene functionalized with amidine (positive surface charge) suspended in isopropanol. Experimental conditions predicted by the theoretical model discussed in a separate talk have been implemented to obtain heterocoagulation of these particles in the rocksalt structure. To our knowledge, this is the first experimental demonstration of the ICC concept. The importance of various experimental parameters on ICC formation is discussed. Particle dynamics simulations are carried out to provide insight into the kinetics of ICCs. Potential applications are discussed.

  20. Color management understanding and using ICC profiles

    CERN Document Server

    Green, Phil

    2010-01-01

    Color Management serves as a comprehensive guide to the implementation of the ICC (International Color Consortium) profile specification, widely used for maintaining color fidelity across multi-media imaging devices and software. The book draws together many of the White Papers produced by the ICC to promote the use of color management and disseminate good practice; the ICC specification has become widely accepted within the color industry, and these papers have been updated, expanded and edited for this collection. Other chapters comprise material that will go on to form future ICC Whi

  1. REMOVING COOL CORES AND CENTRAL METALLICITY PEAKS IN GALAXY CLUSTERS WITH POWERFUL ACTIVE GALACTIC NUCLEUS OUTBURSTS

    International Nuclear Information System (INIS)

    Recent X-ray observations of galaxy clusters suggest that cluster populations are bimodally distributed according to central gas entropy and are separated into two distinct classes: cool core (CC) and non-cool core (NCC) clusters. While it is widely accepted that active galactic nucleus (AGN) feedback plays a key role in offsetting radiative losses and maintaining many clusters in the CC state, the origin of NCC clusters is much less clear. At the same time, a handful of extremely powerful AGN outbursts have recently been detected in clusters, with a total energy ∼1061-1062 erg. Using two-dimensional hydrodynamic simulations, we show that if a large fraction of this energy is deposited near the centers of CC clusters, which is likely common due to dense cores, these AGN outbursts can completely remove CCs, transforming them to NCC clusters. Our model also has interesting implications for cluster abundance profiles, which usually show a central peak in CC systems. Our calculations indicate that during the CC to NCC transformation, AGN outbursts efficiently mix metals in cluster central regions and may even remove central abundance peaks if they are not broad enough. For CC clusters with broad central abundance peaks, AGN outbursts decrease peak abundances, but cannot effectively destroy the peaks. Our model may simultaneously explain the contradictory (possibly bimodal) results of abundance profiles in NCC clusters, some of which are nearly flat, while others have strong central peaks similar to those in CC clusters. A statistical analysis of the sizes of central abundance peaks and their redshift evolution may shed interesting insights on the origin of both types of NCC clusters and the evolution history of thermodynamics and AGN activity in clusters.

  2. Axisymmetric nonstationary model of the central engine in an active galactic nucleus. I. Black hole electrodynamics

    International Nuclear Information System (INIS)

    In a previous paper the authors analyzed an axisymmetric, nonstationary model of the central engine of an active galactic nucleus, consisting of a supermassive black hole surrounded by a magnetized accretion disk. The equations used were the equations of power output and angular momentum loss given by Macdonald and Thorne (1982), in which an axisymmetric, stationary model is described. In this paper, all the fundamental equations in a fully time-dependent manner and the electrodynamics of a black hole and its magnetosphere is investigated. Under the assumption that the mass accretion is confined to the equatorial plane of the black hole, the results suggest that, at the equatorial zone of the black hole, the angular velocity of the magnetic field lines anchored on the accreting matter must be close to that of the black hole. 21 references

  3. Optogenetic stimulation of the cochlear nucleus using channelrhodopsin-2 evokes activity in the central auditory pathway

    Science.gov (United States)

    Darrow, Keith N.; Slama, Michaël C. C.; Owoc, Maryanna; Kozin, Elliott; Hancock, Kenneth; Kempfle, Judith; Edge, Albert; Lacour, Stephanie; Boyden, Edward; Polley, Daniel; Brown, M. Christian; Lee, Daniel J.

    2016-01-01

    Optogenetics has become an important research tool and is being considered as the basis for several neural prostheses. However, few studies have applied optogenetics to the auditory brainstem. This study explored whether optical activation of the cochlear nucleus (CN) elicited responses in neurons in higher centers of the auditory pathway, and it measured the evoked response to optical stimulation. Viral-mediated gene transfer was used to express channelrhodopsin-2 (ChR2) in the mouse CN. Blue light was delivered via an optical fiber placed near the surface of the infected CN and recordings were made in higher-level centers. Optical stimulation evoked excitatory multiunit spiking activity throughout the tonotopic axis of central nucleus of the inferior colliculus (IC) and the auditory cortex (Actx). The pattern and magnitude of IC activity elicited by optical stimulation was comparable to that obtained with a 50 dB SPL acoustic click stimulus. This broad pattern of activity was consistent with histological confirmation of GFP label of cell bodies and axons throughout the CN. Increasing pulse rates up to 320 Hz did not significantly affect threshold or bandwidth of the IC responses, but rates higher than 50 Hz resulted in desynchronized activity. Optical stimulation also evoked an auditory brainstem response, which had a simpler waveform than the response to acoustic stimulation. Control cases showed no responses to optical stimulation. These data suggest that optogenetic control of central auditory neurons is feasible, but opsins with faster channel kinetics will be necessary to convey information in rates typical of many auditory signals. PMID:25481416

  4. SUNSETTING THE ICC: IS IT REALLY DEAD?

    Directory of Open Access Journals (Sweden)

    Richard D. Stone

    2004-01-01

    Full Text Available The Interstate Commerce Commission (ICC was created in 1887 to regulate railroads. By the mid-1970’s it had grown into the premier independent agency in the federal government, regulating all domestic transport modes except air. But starting in the ‘70’s, the Commission began to shrink in both size and power. By 1995’s end, it disappeared, and was replaced by the Surface Transportation Board (STB that regulates only railroads, although to a lesser extent than the ICC had. There remains the question of whether the ICC is really dead or just renamed.

  5. Central and peripheral contributions to dynamic changes in nucleus accumbens glucose induced by intravenous cocaine

    Directory of Open Access Journals (Sweden)

    Ken Taro Wakabayashi

    2015-02-01

    Full Text Available The pattern of neural, physiological and behavioral effects induced by cocaine is consistent with metabolic neural activation, yet direct attempts to evaluate central metabolic effects of this drug have produced controversial results. Here, we used enzyme-based glucose sensors coupled with high-speed amperometry in freely moving rats to examine how intravenous cocaine at a behaviorally active dose affects extracellular glucose levels in the nucleus accumbens (NAc, a critical structure within the motivation-reinforcement circuit. In drug-naive rats, cocaine induced a bimodal increase in glucose, with the first, ultra-fast phasic rise appearing during the injection (latency 6-8 s; ~50 µM or ~5% of baseline followed by a larger, more prolonged tonic elevation (~100 µM or 10% of baseline, peak ~15 min. While the rapid, phasic component of the glucose response remained stable following subsequent cocaine injections, the tonic component progressively decreased. Cocaine-methiodide, cocaine’s peripherally acting analog, induced an equally rapid and strong initial glucose rise, indicating cocaine’s action on peripheral neural substrates as its cause. However, this analog did not induce increases in either locomotion or tonic glucose, suggesting direct central mediation of these cocaine effects. Under systemic pharmacological blockade of dopamine transmission, both phasic and tonic components of the cocaine-induced glucose response were only slightly reduced, suggesting a significant role of non-dopamine mechanisms in cocaine-induced accumbal glucose influx. Hence, intravenous cocaine induces rapid, strong inflow of glucose into NAc extracellular space by involving both peripheral and central, non-dopamine drug actions, thus preventing a possible deficit resulting from enhanced glucose use by brain cells.

  6. Cell death in the central division of the medial preoptic nucleus of male and female lamb fetuses

    OpenAIRE

    Reddy, Radhika C.; Scheldrup, Melissa; Meaker, Mary; Stormshak, Fred; Estill, Charles T.; Roselli, Charles E.

    2014-01-01

    The medial preoptic area of the adult sheep contains an ovine sexually dimorphic nucleus (oSDN) that is larger and has more neurons in males than in females. In the lamb fetus, the nascent oSDN occupies the central division of the medial preoptic nucleus (MPNc) and consists of a cluster of cells that is organized by the action of testosterone during gestational days 60 to 90 of a 147 day term pregnancy. The current study sought to determine whether programmed cell death cont...

  7. ICCS 2009 User Guide for the International Database. Supplement 5: ICCS 2009 Released Items

    Science.gov (United States)

    Brese, Falk; Jung, Michael; Mirazchiyski, Plamen; Schulz, Wolfram; Zuehlke, Olaf

    2011-01-01

    This document contains released items used in the ICCS 2009 main survey. Seven clusters of items were used in the study in a rotated booklet design with three clusters per test booklet. Clusters 1 and 7 comprise the released item set. Cluster 1 comprises items that were newly developed for ICCS 2009 and Cluster 7 is drawn from previously secure…

  8. No limit to fusion in nucleus-nucleus central collisions. Study of 40Ar on 27Al from 25 to 85 MeV/u

    International Nuclear Information System (INIS)

    Light charged particles and fragments emitted in collisions between 40Ar projectiles (from 25 to 85 MeV/u) and 27Al target nuclei have been detected in a 2Π geometry, i.e. nearly 4Π in the center-of-mass frame. An event-by-event analysis based on the use of the momentum sphericity tensor allowed to identify part of the central collision events. The angular distribution of light charged particles and fragments show that an incomplete fusion nucleus is formed and decays via isotropic emission at all incident energies, although no heavy residue is left above 36 MeV/u. Fusion is less and less complete as the incident energy increases. Nevertheless, a steady increase in the multiplicity of charged particles shows that the average excitation energy increases

  9. Niobium-3-tin internally cooled cabled superconductor (ICCS) technology II

    International Nuclear Information System (INIS)

    In addition to the development of compaction-degradation-free ICCS conductors using alternate sheathing materials, we are reporting on the improvement in current density of stainless steel sheathed, compacted ICCS due to optimized reaction conditions

  10. NIF ICCS network design and loading analysis

    International Nuclear Information System (INIS)

    The National Ignition Facility (NIF) is housed within a large facility about the size of two football fields. The Integrated Computer Control System (ICCS) is distributed throughout this facility and requires the integration of about 40,000 control points and over 500 video sources. This integration is provided by approximately 700 control computers distributed throughout the NIF facility and a network that provides the communication infrastructure. A main control room houses a set of seven computer consoles providing operator access and control of the various distributed front-end processors (FEPs). There are also remote workstations distributed within the facility that allow provide operator console functions while personnel are testing and troubleshooting throughout the facility. The operator workstations communicate with the FEPs which implement the localized control and monitoring functions. There are different types of FEPs for the various subsystems being controlled. This report describes the design of the NIF ICCS network and how it meets the traffic loads that will are expected and the requirements of the Sub-System Design Requirements (SSDR's). This document supersedes the earlier reports entitled Analysis of the National Ignition Facility Network, dated November 6, 1996 and The National Ignition Facility Digital Video and Control Network, dated July 9, 1996. For an overview of the ICCS, refer to the document NIF Integrated Computer Controls System Description (NIF-3738)

  11. ICCS 2009 User Guide for the International Database. Supplement 1: International Version of the ICCS 2009 Questionnaires

    Science.gov (United States)

    Brese, Falk; Jung, Michael; Mirazchiyski, Plamen; Schulz, Wolfram; Zuehlke, Olaf

    2011-01-01

    This document presents Supplement 1 of "The International Civic and Citizenship Education Study (ICCS) 2009 International Database," which includes data for all questionnaires administered as part of the ICCS 2009 assessment. This supplement contains the international version of the ICCS 2009 questionnaires in the following seven…

  12. ICCS 2009 User Guide for the International Database. Supplement 4: ICCS 2009 Sampling Stratification Information

    Science.gov (United States)

    Brese, Falk; Jung, Michael; Mirazchiyski, Plamen; Schulz, Wolfram; Zuehlke, Olaf

    2011-01-01

    This supplement contains documentation on the explicit and implicit stratification variables included in the International Civic and Citizenship Education Study (ICCS) 2009 data files. The explicit strata are smaller sampling frames, created from the national sampling frames, from which national samples of schools were drawn. The implicit strata…

  13. On validity of the data from commonly used ICC tables

    International Nuclear Information System (INIS)

    It is shown that in tables of internal conversion coefficients (ICC) calculated by Roesel et al. the ICC values are given with notable errors for a large number of cases. Errors are particularly high (up to 30 %) for magnetic transitions on all p1/2, d3/2, f5/2 shells of heavy atoms with Z≥70. To examine Roesel data, ICC calculations are performed within the framework of physical assumption used

  14. The precise ICC measurement of the high multipolarity transitions

    International Nuclear Information System (INIS)

    The methods of γ-spectroscopy are used to measure internal conversion coefficients (ICC) on the K-shell and total ICC for M4,E4,E5-multipolarity transitions. The research is carried out using the 202,204Pb, 197Pt,114In isomers. The data obtained prove that the observed systematic excess of theoretical ICC for M4-multipolarity transitions as compared with the experimental values is most probably connected with the contribution of ''intranuclear'' conversion

  15. The central region of M83: Massive star formation, kinematics, and the location and origin of the nucleus

    CERN Document Server

    Knapen, J H; Ryder, S D; Falcon-Barroso, J; Fathi, K; Gutierrez, L

    2010-01-01

    We report new near-IR integral field spectroscopy of the central starburst region of the barred spiral galaxy M83 obtained with CIRPASS on Gemini-S, which we analyse in conjunction with GHaFaS Fabry-Perot data, an AAT IRIS2 Ks-band image, and near- and mid-IR imaging from the Hubble and Spitzer space telescopes. The bulk of the current star formation activity is hidden from optical view by dust extinction, but is seen in the near- and mid-IR to the north of the nucleus. This region is being fed by inflow of gas through the bar of M83, traced by the prominent dust lane entering into the circumnuclear region from the north. An analysis of stellar ages confirms that the youngest stars are indeed in the northwest. A gradual age gradient, with older stars further to the south, characterises the well-known star-forming arc in the central region of M83. Detailed analyses of the Pa beta ionised gas kinematics and near-IR imaging confirm that the kinematic centre coincides with the photometric centre of M83, and that ...

  16. X-ray Supercavities in the Hydra A Cluster and the Outburst History of the Central Galaxy's Active Nucleus

    CERN Document Server

    Wise, M W; Nulsen, P E J; Houck, J C; David, L P

    2006-01-01

    A 227 ksec Chandra Observatory X-ray image of the hot plasma in the Hydra A cluster has revealed an extensive cavity system. The system was created by a continuous outflow or a series of bursts from the nucleus of the central galaxy over the past 200-500 Myr. The cavities have displaced 10% of the plasma within a 300 kpc radius of the central galaxy, creating a swiss-cheese-like topology in the hot gas. The surface brightness decrements are consistent with empty cavities oriented within 40 degrees of the plane of the sky. The outflow has deposited upward of 10^61 erg into the cluster gas, most of which was propelled beyond the inner ~100 kpc cooling region. The supermassive black hole has accreted at a rate of approximately 0.1-0.25 solar masses per year over this time frame, which is a small fraction of the Eddington rate of a ~10^9 solar mass black hole, but is dramatically larger than the Bondi rate. Given the previous evidence for a circumnuclear disk of cold gas in Hydra A, these results are consistent w...

  17. Integration of stress and leptin signaling by CART producing neurons in the rodent midbrain centrally projecting Edinger-Westphal nucleus

    Science.gov (United States)

    Xu, Lu; Janssen, Donny; van der Knaap, Noortje; Roubos, Eric W.; Leshan, Rebecca L.; Myers, Martin G.; Gaszner, Balázs; Kozicz, Tamás

    2014-01-01

    Leptin targets the brain to regulate feeding, neuroendocrine function and metabolism. The leptin receptor is present in hypothalamic centers controlling energy metabolism as well as in the centrally projecting Edinger–Westphal nucleus (EWcp), a region implicated in the stress response and in various aspects of stress-related behaviors. We hypothesized that the stress response by cocaine- and amphetamine-regulated transcript (CART)-producing EWcp-neurons would depend on the animal’s energy state. To test this hypothesis, we investigated the effects of changes in energy state (mimicked by low, normal and high leptin levels, which were achieved by 24 h fasting, normal chow and leptin injection, respectively) on the response of CART neurons in the EWcp of rats subjected or not to acute restraint stress. Our data show that leptin treatment alone significantly increases CART mRNA expression in the rat EWcp and that in leptin receptor deficient (db/db) mice, the number of CART producing neurons in this nucleus is reduced. This suggests that leptin has a stimulatory effect on the production of CART in the EWcp under non-stressed condition. Under stressed condition, however, leptin blunts stress-induced activation of EWcp neurons and decreases their CART mRNA expression. Interestingly, fasting, does not influence the stress-induced activation of EWcp-neurons, and specifically EWcp-CART neurons are not activated. These results suggest that the stress response by the EWcp depends to some degree on the animal’s energy state, a mechanism that may contribute to a better understanding of the complex interplay between obesity and stress. PMID:24624061

  18. Integration of stress and leptin signaling by CART producing neurons in the rodent midbrain centrally projecting Edinger-Westphal nucleus

    Directory of Open Access Journals (Sweden)

    Lu eXu

    2014-03-01

    Full Text Available Leptin targets the brain to regulate feeding, neuroendocrine function and metabolism. The leptin receptor is present in hypothalamic centers controlling energy metabolism as well as in the centrally projecting Edinger-Westphal nucleus (EWcp, a region implicated in the stress response and in various aspects of stress-related behaviors. We hypothesized that the stress response by cocaine- and amphetamine-regulated transcript (CART-producing EWcp-neurons would depend on the animal’s energy state. To test this hypothesis, we investigated the effects of changes in energy state (mimicked by low, normal and high leptin levels, which were achieved by 24h fasting, normal chow and leptin injection, respectively on the response of CART neurons in the EWcp of rats subjected or not to acute restraint stress. Our data show that leptin treatment alone significantly increases CART mRNA expression in the rat EWcp and that in leptin receptor deficient (db/db mice, the number of CART producing neurons in this nucleus is reduced. This suggests that leptin has a stimulatory effect on the production of CART in the EWcp under non-stressed condition. Under stressed condition, however, leptin blunts stress-induced activation of EWcp neurons and decreases their CART mRNA expression. Interestingly, fasting, does not influence the stress-induced activation of EWcp-neurons, and specifically EWcp-CART neurons are not activated. These results suggest that the stress response by the EWcp depends to some degree on the animal’s energy state, a mechanism that may contribute to a better understanding of the complex interplay between obesity and stress.

  19. ICCS 2009 User Guide for the International Database

    Science.gov (United States)

    Brese, Falk; Jung, Michael; Mirazchiyski, Plamen; Schulz, Wolfram; Zuehlke, Olaf

    2011-01-01

    The International Civic and Citizenship Education Study (ICCS) 2009 studied the ways in which countries prepare their young people to undertake their roles as citizens. ICCS 2009 was based on the premise that preparing students for citizenship roles involves helping them develop relevant knowledge and understanding and form positive attitudes…

  20. Transient cooling in internally cooled, cabled superconductors (ICCS)

    International Nuclear Information System (INIS)

    Rapid heat transfer is reported in transiently heated copper capillaries containing stagnant supercritical helium. The hydraulic diameter and metal-to-liquid ratio of these capillaries are similar to typical ICCS characteristics and simulate ICCS heat transfer behavior. The characteristic cooling time of capillaries was found experimentally to be simply related to the heated length and speed of sound in helium. The ICCS stability margin could be estimated from the measured fluid temperature in the heated zone once equilibrium temperatures had been re-established. These experimental results can be predicted by a computer code. The code also predicts ICCS stability margins by accounting for induced helium flow. The correlation of experiment and theory seemingly supports the hypothesis that locally induced helium flow is responsible for unexpectedly high ICCS recovery characteristics. 7 refs

  1. Sustainable development - the ICC business charter

    International Nuclear Information System (INIS)

    The International Chamber of Commerce (ICC) prepared and approved, in November 1990, the ''Business Charter for Sustainable Development; a set of principles for environmental management''. Environmental protection is a necessary part of sustainable development but, too often, the performance of business is seen by society as inadequate. Improved environmental performance is essential if business is to regain public trust, reduce the pressures on governments to over-legislate, and strengthen the business voice in debate on public policy. The Charter has been prepared as a major pro-active business initiative by enterprises around the world. This is timely in view of the extensive international debate on environmental issues and the widespread acceptance of the ''Sustainable Development'' concept. Sustainable development involves meeting the needs of the present without compromising the ability of future generations to meet their own needs. Although the objective of the Charter is that the widest range of enterprises as organizations commit themselves to improving their environmental performance in accordance with the Principles of the Charter, an individual branch of industry may also meet the goals of the Charter. The paper evaluates how the practices implemented in the field of nuclear energy are in harmony with the principles. The conclusion is that nuclear is in the avant garde within the wide spectrum of industrial activities. This conclusion should assist nuclear energy to improve its public acceptance. (author)

  2. Review: ICCS International Civics and Citizenship Study

    Directory of Open Access Journals (Sweden)

    Anu Toots

    2010-11-01

    Full Text Available In November 2010 the largest international study ever conducted on civic education in secondary schools has been released in Brussels. The study was performed under the auspices of the International Association for the Evaluation of Educational Achievement (IEA, an independent consortium that brings together educational researchers and policy makers in 62 countries around the world. The IEA is probably more widely known in connection of large-scale comparative studies on educational assessment in math and science (TIMSS and in reading (PIRLS. Yet, the association has longstanding and impressive expertise also in civic education. The first study in this area has been carried out already in 1971 (Torney et al., 1975, the second – so called CIVED in 1999 (Torney-Purta et al., 2001 and now, ten years later, 38 counties around the world participated in the third study – the IEA International Civic and Citizenship Education Study (ICCS. The study tested in 2008–2009 over 140,000 lower secondary students, over 62,000 teachers and headmasters from 5,300 schools in order to analyse how young people are prepared to undertake their roles as citizens.

  3. Effect of monaural and binaural stimulation on cytoplasmic RNA content in cells of the central nucleus of the cat inferior colliculus.

    Science.gov (United States)

    Shmigidina, G N

    1981-01-01

    A cytophotometric study of sections stained with gallocyanin and chrome alum showed that monaural stimulation for 2 h and binaural stimulation for 1.5 h with rhythmic noise signals led to a marked increase in the cytoplasmic RNA content per cell in the principal and large multipolar neurons of the dorsal and ventral parts of the ventrolateral region of the central nucleus of the inferior colliculus. The increase in cytoplasmic RNA content in the principal cells of the ipsi- and contralateral parts of this nucleus relative to the stimulated ear in the case of monaural stimulation and the increase in RNA content in response to binaural stimulation suggests a uniform distribution of bilaterally converging connections from the lower nuclei of the auditory system on the principal cells. The increase in cytoplasmic RNA in the large multipolar cells of the contralateral central nucleus in response to monaural stimulation is evidence of the predominantly contralateral projection to these cells. The results are evidence of convergence of binaural influences on the principal and large multipolar cells of the central nucleus of the inferior colliculus. PMID:6173796

  4. Mammal-like organization of the avian midbrain central gray and a reappraisal of the intercollicular nucleus.

    Directory of Open Access Journals (Sweden)

    Marcy A Kingsbury

    Full Text Available In mammals, rostrocaudal columns of the midbrain periaqueductal gray (PAG regulate diverse behavioral and physiological functions, including sexual and fight-or-flight behavior, but homologous columns have not been identified in non-mammalian species. In contrast to mammals, in which the PAG lies ventral to the superior colliculus and surrounds the cerebral aqueduct, birds exhibit a hypertrophied tectum that is displaced laterally, and thus the midbrain central gray (CG extends mediolaterally rather than dorsoventrally as in mammals. We therefore hypothesized that the avian CG is organized much like a folded open PAG. To address this hypothesis, we conducted immunohistochemical comparisons of the midbrains of mice and finches, as well as Fos studies of aggressive dominance, subordinance, non-social defense and sexual behavior in territorial and gregarious finch species. We obtained excellent support for our predictions based on the folded open model of the PAG and further showed that birds possess functional and anatomical zones that form longitudinal columns similar to those in mammals. However, distinguishing characteristics of the dorsal/dorsolateral PAG, such as a dense peptidergic innervation, a longitudinal column of neuronal nitric oxide synthase neurons, and aggression-induced Fos responses, do not lie within the classical avian CG, but in the laterally adjacent intercollicular nucleus (ICo, suggesting that much of the ICo is homologous to the dorsal PAG.

  5. Igf1r+/CD34+ immature ICC are putative adult progenitor cells, identified ultrastructurally as fibroblast-like ICC in Ws/Ws rat colon

    DEFF Research Database (Denmark)

    Wang, X Y; Albertí, E; White, E J; Mikkelsen, Hanne Birte; Larsen, Jytte Overgaard; Jiménez, M; Huizinga, J D

    (ICC-AP) were significantly decreased and ICC located at the submuscular plexus and intramuscular ICC were rarely observed based on immunohistochemistry and electron microscopy. Ultrastructural investigations revealed that there was no overall loss of all types of interstitial cells combined. Where...... loss of ICC was observed, a marked increase in fibroblast-like ICC (FL-ICC) was found at the level of AP. Immunoelectron microscopy proved FL-ICC to be c-Kit(-) but gap junction coupled to each other and to c-Kit(+) ICC; they were associated with enteric nerves and occupied space normally occupied by...... ICC in the wild-type rat colon, suggesting them to be immature ICC. In addition, a marked increase in immunoreactivity for insulin-like growth factor 1 receptor (Igf1r) occurred, co-localized with CD34 but not with c-Kit. A significantly higher number of Igf1r(+)/CD34(+) cells were found in Ws...

  6. Acute tianeptine treatment selectively modulates neuronal activation in the central nucleus of the amygdala and attenuates fear extinction.

    Science.gov (United States)

    Godsil, B P; Bontempi, B; Mailliet, F; Delagrange, P; Spedding, M; Jay, T M

    2015-11-01

    Antidepressant drugs are commonly prescribed treatments for anxiety disorders, and there is growing interest in understanding how these drugs impact fear extinction because extinction learning is pivotal to successful exposure-based therapy (EBT). A key objective within this domain is understanding how antidepressants alter the activation of specific elements of the limbic-based network that governs such fear processing. Chronic treatment with the antidepressant tianeptine has been shown to reduce the acquisition of extinction learning in rats, yet the drug's acute influence on activation in prefrontal and amygdalar regions, and on extinction learning are not well understood. To assess its influence on cellular activation, rats were injected with tianeptine and Fos immunoreactivity was measured in these regions. Acute tianeptine treatment selectively altered Fos expression within subdivisions of the central nucleus of the amygdala (CEA) in a bidirectional manner that varied in relation to ongoing activation within the capsular subdivision and its prefrontal and intra-amygdalar inputs. This pattern of results suggests that the drug can conditionally modulate the activation of CEA subdivisions, which contain microcircuits strongly implicated in fear processing. The effect of acute tianeptine was also examined with respect to the acquisition, consolidation and expression of fear extinction in rats. Acute tianeptine attenuated extinction learning as well as the recall of extinction memory, which underscores that acute dosing with the drug could alter learning during EBT. Together these findings provide a new perspective for understanding the mechanism supporting tianeptine's clinical efficacy, as well as its potential influence on CEA-based learning mechanisms. PMID:25560759

  7. Inactivation of the central nucleus of the amygdala reduces the effect of punishment on cocaine self-administration in rats.

    Science.gov (United States)

    Xue, YueQiang; Steketee, Jeffery D; Sun, WenLin

    2012-03-01

    Continued cocaine use despite the negative consequences is a hallmark of cocaine addiction. One such consequence is punishment, which is often used by society to curb cocaine use. Unfortunately, we know little about the mechanism involved in regulation by punishment of cocaine use. The fact that cocaine addicts continue to use cocaine despite potentially severe punishment suggests that the mechanism may be impaired. Such impairment is expected to critically contribute to compulsive cocaine use. This study was aimed at testing the hypothesis that the central nucleus of the amygdala (CeN) plays a critical role in such regulation. To this end, rats were trained to press a lever to self-administer cocaine under a chained schedule: a response on one lever (cocaine-seeking lever) led to access to the other lever (cocaine-taking lever), on which a response was reinforced by cocaine and cues. Thereafter, responses on the seeking lever were punished by footshock with a probability of 0.5. Cocaine self-administration (SA) was significantly suppressed by punishment in an intensity-dependent manner. Interestingly, rats trained with daily 6-h (extended access) but not 2-h (limited access) sessions showed resistance to the lower intensity of punishment. Inactivation of the CeN induced a robust anti-punishment effect in both groups. These data provided evidence that the CeN is a critical neural substrate involved in regulation by punishment of cocaine SA. Rats with a history of extended cocaine SA appeared to be less sensitive to punishment. The decreased sensitivity could result from the neuroplastic changes induced by extended cocaine SA in the CeN. PMID:22304754

  8. ULTRASTRUCTURAL RELATIONSHIP BETWEEN N-METHYL-d-ASPARTATE-NR1 RECEPTOR SUBUNIT AND MU-OPIOID RECEPTOR IN THE MOUSE CENTRAL NUCLEUS OF THE AMYGDALA

    OpenAIRE

    Glass, M. J.; Vanyo, L.; Quimson, L.; Pickel, V.M.

    2009-01-01

    The central nucleus of the amygdala (CeA) is an important neuroanatomical substrate of emotional processes that are critically involved in addictive behaviors. Glutamate and opioid systems in the CeA play significant roles in neural plasticity and addictive processes, however the cellular sites of interaction between agonists of N-methyl-d-aspar-tate (NMDA) and μ-opioid receptors (μOR) in the CeA are unknown. Dual labeling immunocytochemistry was used to determine the ultrastructural relation...

  9. Central stress-integrative circuits: Forebrain glutamatergic and GABAergic projections to the dorsomedial hypothalamus, medial preoptic area, and bed nucleus of the stria terminalis

    OpenAIRE

    Myers, Brent; Dolgas, C. Mark; Kasckow, John; Cullinan, William E.; Herman, James P.

    2013-01-01

    Central regulation of hypothalamo-pituitary-adrenocortical (HPA) axis stress responses is mediated by a relatively circumscribed group of projections to the paraventricular hypothalamus (PVN). The dorsomedial hypothalamus (DMH), medial preoptic area (mPOA), and bed nucleus of the stria terminalis (BST) provide direct, predominantly inhibitory, innervation of the PVN. These PVN-projecting neurons are controlled by descending information from limbic forebrain structures, including the prefronta...

  10. Figuring out the Statistics of the ICC World Cup 2011

    Science.gov (United States)

    Shiwalkar, Jyoti P.; Deshpande, M. N.

    2013-01-01

    This paper deals with the analysis of cricket match results from the ICC World Cup 2011. We believe that such data provide good material for interesting classroom exercises. (Contains 7 tables and 1 figure.)

  11. Evaluation of theoretical conversion coefficients using BrIcc

    International Nuclear Information System (INIS)

    A new internal conversion coefficient database, BrIcc has been developed which integrates a number of tabulations on internal conversion electron (ICC) and electron-positron pair conversion coefficients (IPC), as well as Ω(E0) electronic factors. A critical review of general formulae and procedures to evaluate theoretical ICC and IPC values are presented, including the treatment of uncertainties in transition energy and mixing ratio in accordance with the Evaluated Nuclear Structure Data File. The default ICC table, based on the Dirac-Fock calculations using the so called 'Frozen Orbital' approximation, takes into account the effect of atomic vacancies created in the conversion process. The table has been calculated for all atomic shells and to cover transition energies of 1-6000 keV and atomic numbers of Z=5-110. The software tools presented here are well suited for basic nuclear structure research and for a range of applications

  12. Quality Control, Testing and Deployment Results in NIF ICCS

    OpenAIRE

    Woodruff, John P.; Casavant, Drew D.; Cline, Barry D.; Gorvad, Michael R.

    2001-01-01

    The strategy used to develop the NIF Integrated Computer Control System (ICCS) calls for incremental cycles of construction and formal test to deliver a total of 1 million lines of code. Each incremental release takes four to six months to implement specific functionality and culminates when offline tests conducted in the ICCS Integration and Test Facility verify functional, performance, and interface requirements. Tests are then repeated on line to confirm integrated operation in dedicated l...

  13. NIF ICCS Test Controller for Automated and Manual Testing

    International Nuclear Information System (INIS)

    The National Ignition Facility (NIF) Integrated Computer Control System (ICCS) is a large (1.5 MSLOC), hierarchical, distributed system that controls all aspects of the NIF laser [1]. The ICCS team delivers software updates to the NIF facility throughout the year to support shot operations and commissioning activities. In 2006, there were 48 releases of ICCS: 29 full releases, 19 patches. To ensure the quality of each delivery, thousands of manual and automated tests are performed using the ICCS Test Controller test infrastructure. The TestController system provides test inventory management, test planning, automated test execution and manual test logging, release testing summaries and test results search, all through a web browser interface. Automated tests include command line based frameworks server tests and Graphical User Interface (GUI) based Java tests. Manual tests are presented as a checklist-style web form to be completed by the tester. The results of all tests, automated and manual, are kept in a common repository that provides data to dynamic status reports. As part of the 3-stage ICCS release testing strategy, the TestController system helps plan, evaluate and track the readiness of each release to the NIF facility

  14. Weak orientation and direction selectivity in lateral geniculate nucleus representing central vision in the gray squirrel Sciurus carolinensis

    NARCIS (Netherlands)

    Zaltsman, Julia B; Heimel, J Alexander; Van Hooser, Stephen D

    2015-01-01

    Classic studies of lateral geniculate nucleus (LGN) and visual cortex (V1) in carnivores and primates have found that a majority of neurons in LGN exhibit a center-surround organization, while V1 neurons exhibit strong orientation selectivity and, in many species, direction selectivity. Recent work

  15. Calcitonin gene-related peptide erases the fear memory and facilitates long-term potentiation in the central nucleus of the amygdala in rats.

    Science.gov (United States)

    Wu, Xin; Zhang, Jie-Ting; Liu, Jue; Yang, Si; Chen, Tao; Chen, Jian-Guo; Wang, Fang

    2015-11-01

    Calcitonin gene-related peptide (CGRP) is a 37 amino acid neuropeptide, which plays a critical role in the central nervous system. CGRP binds to G protein-coupled receptors, including CGRP1, which couples positively to adenylyl cyclase (AC) and protein kinase A (PKA) activation. CGRP and CGRP1 receptors are enriched in central nucleus of the amygdala (CeA), the main part of the amygdala, which regulates conditioned fear memories. Here, we reported the importance of CGRP and CGRP1 receptor for synaptic plasticity in the CeA and the extinction of fear memory in rats. Our electrophysiological and behavioral in vitro and in vivo results showed exogenous application of CGRP induced an immediate and lasting long-term potentiation in the basolateral nucleus of amygdala-CeA pathway, but not in the lateral nucleus of amygdala-CeA pathway, while bilateral intra-CeA infusion CGRP (0, 5, 13 and 21 μM/side) dose dependently enhanced fear memory extinction. The effects were blocked by CGRP1 receptor antagonist (CGRP8-37 ), N-methyl-d-aspartate receptors antagonist MK801 and PKA inhibitor H89. These results demonstrate that CGRP can lead to long-term potentiation of basolateral nucleus of amygdala-CeA pathway through a PKA-dependent postsynaptic mechanism that involved N-methyl-d-aspartate receptors and enhance the extinction of fear memory in rats. Together, the results strongly support a pivotal role of CGRP in the synaptic plasticity of CeA and extinction of fear memory. Calcitonin gene-related peptide (CGRP) plays an essential role in synaptic plasticity in the amygdala and fear memory. We found that CGRP-induced chemical long-term potentiation (LTP) in a dose-dependent way in the BLA-CeA (basolateral and central nucleus of amygdala, respectively) pathway and enhanced fear memory extinction in rats through a protein kinase A (PKA)-dependent postsynaptic mechanism that involved NMDA receptors. These results support a pivotal role of CGRP in amygdala. PMID:26179152

  16. PREFACE: 3rd International Congress on Ceramics (ICC3)

    Science.gov (United States)

    Niihara, Koichi; Ohji, Tatsuki; Sakka, Yoshio

    2011-10-01

    Early in 2005, the American Ceramic Society, the European Ceramic Society and the Ceramic Society of Japan announced a collaborative effort to provide leadership for the global ceramics community that would facilitate the use of ceramic and glass materials. That effort resulted in an agreement to organize a new biennial series of the International Congress on Ceramics, convened by the International Ceramic Federation (ICF). In order to share ideas and visions of the future for ceramic and glass materials, the 1st International Congress on Ceramics (ICC1) was held in Canada, 2006, under the organization of the American Ceramic Society, and the 2nd Congress (ICC2) was held in Italy, 2008, hosted by the European Ceramic Society. Organized by the Ceramic Society of Japan, the 3rd Congress (ICC3) was held in Osaka, Japan, 14-18 November 2010. Incorporating the 23rd Fall Meeting of the Ceramic Society of Japan and the 20th Iketani Conference, ICC3 was also co-organized by the Iketani Science and Technology Foundation, and was endorsed and supported by ICF, Asia-Oceania Ceramic Federation (AOCF) as well as many other organizations. Following the style of the previous two successful Congresses, the program was designed to advance ceramic and glass technologies to the next generation through discussion of the most recent advances and future perspectives, and to engage the worldwide ceramics community in a collective effort to expand the use of these materials in both conventional as well as new and exciting applications. ICC3 consisted of 22 voluntarily organized symposia in the most topical and essential themes of ceramic and glass materials, including Characterization, design and processing technologies Electro, magnetic and optical ceramics and devices Energy and environment related ceramics and systems Bio-ceramics and bio-technologies Ceramics for advanced industry and safety society Innovation in traditional ceramics It also contained the Plenary Session and the

  17. Effects of location and timing of co-activated neurons in the auditory midbrain on cortical activity: implications for a new central auditory prosthesis

    Science.gov (United States)

    Straka, Małgorzata M.; McMahon, Melissa; Markovitz, Craig D.; Lim, Hubert H.

    2014-08-01

    Objective. An increasing number of deaf individuals are being implanted with central auditory prostheses, but their performance has generally been poorer than for cochlear implant users. The goal of this study is to investigate stimulation strategies for improving hearing performance with a new auditory midbrain implant (AMI). Previous studies have shown that repeated electrical stimulation of a single site in each isofrequency lamina of the central nucleus of the inferior colliculus (ICC) causes strong suppressive effects in elicited responses within the primary auditory cortex (A1). Here we investigate if improved cortical activity can be achieved by co-activating neurons with different timing and locations across an ICC lamina and if this cortical activity varies across A1. Approach. We electrically stimulated two sites at different locations across an isofrequency ICC lamina using varying delays in ketamine-anesthetized guinea pigs. We recorded and analyzed spike activity and local field potentials across different layers and locations of A1. Results. Co-activating two sites within an isofrequency lamina with short inter-pulse intervals (<5 ms) could elicit cortical activity that is enhanced beyond a linear summation of activity elicited by the individual sites. A significantly greater extent of normalized cortical activity was observed for stimulation of the rostral-lateral region of an ICC lamina compared to the caudal-medial region. We did not identify any location trends across A1, but the most cortical enhancement was observed in supragranular layers, suggesting further integration of the stimuli through the cortical layers. Significance. The topographic organization identified by this study provides further evidence for the presence of functional zones across an ICC lamina with locations consistent with those identified by previous studies. Clinically, these results suggest that co-activating different neural populations in the rostral-lateral ICC rather

  18. Niobium-3-tin internally cooled cabled superconductor (ICCS) technology I

    International Nuclear Information System (INIS)

    Recent work, using tantalum and Incoloy 903 sheathing has demonstrated that internally cooled, cabled superconductors (ICCS) can be compacted without current degradation. This paper compares Inconel 617 sheathing to previous results. Inconel 617 is a practical engineering material with a thermal contraction lying between stainless steel and Incoloy 903

  19. NIOBIUM-3-TIN INTERNALLY COOLED CABLED SUPERCONDUCTOR (ICCS) TECHNOLOGY I

    OpenAIRE

    Hoenig, M.; Steeves, M.; Cyders, C.

    1984-01-01

    Recent work, using tantalum and Incoloy 903 sheathing has demonstrated that internally cooled, cabled superconductors (ICCS) can be compacted without current degradation. This paper compares Inconel 617 sheathing to previous results. Inconel 617 is a practical engineering material with a thermal contraction lying between stainless steel and Incoloy 903.

  20. ICCS 2009 Encyclopedia: Approaches to Civic and Citizenship Education

    Science.gov (United States)

    Ainley, John, Ed.; Schulz, Wolfram, Ed.; Friedman, Tim, Ed.

    2013-01-01

    The International Civic and Citizenship Education Study (ICCS) is the largest international study of civic and citizenship education ever conducted. Over 140,000 Grade 8 students, 62,000 teachers, and 5,300 school principals from 38 countries participated in this study. Among these were five from Asia, 26 from Europe, six from Latin America, and…

  1. The ICCS Code: A New Development for an Old Problem

    OpenAIRE

    Mendenhall, Stanley

    1987-01-01

    CPHA has developed a new classification system for hospital services, the ICCS (International Classification of Clinical Services). The codes are designed to organize hospital billing data so it is more accessible and useful for both clinical and financial applications. This coding structure has been adopted by over 100 hospitals in the United States since the beginning of 1987.

  2. Primary coolant pump measurement for ICC trend analysis

    International Nuclear Information System (INIS)

    Reactor coolant pump motor power and temperature measurements are used by Babcock and Wilcox (BandW) plant owners to calculate void fraction for trending ICC conditions while the pumps are running. This new measurement technology satisfies NUREG 0737, Item II.F.2, ''. . . licensees shall provide . . . additional instrumentation . . . to supplement existing instrumentation in order to provide a unambiguous, easy-to-interpret indication of inadequate core cooling.'' System accuracy, capability, and limitations are compared to measurement requirements using small break test data and full scale plant analytical studies. Small break experimental data shows that ICC void fraction calculations are conservative compared to gamma densitometer void fraction measurements in the pipe just upstream of the pumps and liquid level conductivity probes in the reactor vessel. Analytical studies verify that a measure of void fraction at the pumps is conservative relative to the desired coolant inventory trend conditions in the reactor vessel

  3. Primary coolant pump measurement for ICC trend analysis

    International Nuclear Information System (INIS)

    Reactor coolant pump motor power and temperature measurements are used by Babcock and Wilcock (B and W) plant owners to calculate void fraction for trending ICC conditions while the pumps are running. This new measurement technology satisfies NUREG 0737, Item II.F.2, ''...licensees shall provide...additional instrumentation...to supplement existing instrumentation in order to provide a unambiguous, easy-to-interpret indication of inadequate core cooling. System accuracy, capability, and limitations are compared to measurement requirements using small break test data and full scale plant analytical studies. Small break experimental data shows that ICC void fraction calculations are conservative compared to gamma densitometer void fraction measurements in the pipe just upstream of the pumps and liquid level conductivity probes in the reactor vessel. Analytical studies verify that a measure of void fraction at the pumps is conservative relative to the desired coolant inventory trend conditions in the reactor vessel

  4. NIOBIUM-3-TIN INTERNALLY COOLED CABLED SUPERCONDUCTOR ( ICCS) TECHNOLOGY I I

    OpenAIRE

    Hoenig, M.; Steeves, M.; Cyders, C.

    1984-01-01

    In addition to the development of compaction-degradation-free ICCS conductors using alternate sheathing materials, /1/ we are reporting on the improvement in current density of stainless steel sheathed, compacted ICCS due to optimized reaction conditions.

  5. Tolerance effects of non-steroidal anti-inflammatory drugs microinjected into central amygdala, periaqueductal grey, and nucleus raphe Possible cellular mechanism

    Institute of Scientific and Technical Information of China (English)

    Merab G. Tsagareli; Nana Tsiklauri; Ivliane Nozadze; Gulnaz Gurtskaia

    2012-01-01

    Pain is a sensation related to potential or actual damage in some tissue of the body. The mainstay of medical pain therapy remains drugs that have been around for decades, like non-steroidal anti-inflammatory drugs (NSAIDs), or opiates. However, adverse effects of opiates, particularly tolerance, limit their clinical use. Several lines of investigations have shown that systemic (intraperitoneal) administration of NSAIDs induces antinociception with some effects of tolerance. In this review, we report that repeated microinjection of NSAIDs analgin, clodifen, ketorolac and xefocam into the central nucleus of amygdala, the midbrain periaqueductal grey matter and nucleus raphe magnus in the following 4 days result in progressively less antinociception compared to the saline control testing in the tail-flick reflex and hot plate latency tests. Hence, tolerance develops to these drugs and cross-tolerance to morphine in male rats. These findings strongly support the suggestion of endogenous opioid involvement in NSAIDs antinociception and tolerance in the descending pain-control system. Moreover, the periaqueductal grey-rostral ventro-medial part of medulla circuit should be viewed as a pain-modulation system. These data are important for human medicine. In particular, cross-tolerance between non-opioid and opioid analgesics should be important in the clinical setting.

  6. Interstitial Cells of Cajal (ICC) and Gastrointestinal Stromal Tumor (GIST): facts, speculations, and myths

    OpenAIRE

    Min, K. W.; Leabu, M

    2008-01-01

    Interstitial cells of Cajal (ICC) is a peculiar cell network composed of cells having processes described by the eminent Spanish neuroanatomist of the 19th century, S. Ramon y Cajal. ICC became a fascinating subject to many investigators and it is estimated that there are over 100 publications yearly on the subject related to ICC, in the last three years. Now it is widely accepted that ICC are pace maker cells of the gut and probable progenitor cells of gastrointestinal stromal tumors (GIST)....

  7. Differential effects of naloxone on rewarding electrical stimulation of the central nucleus of the amygdala and parabrachial complex in a place preference study.

    Science.gov (United States)

    Agüera, Antonio D R; García, Raquel; Puerto, Amadeo

    2016-06-01

    The central nucleus of the amygdala (CeA) is considered to be involved in different affective, sensory, regulatory, and acquisition processes. This study analyzed whether electrical stimulation of the PB-CeA system induces preferences in a concurrent place preference (cPP) task, as observed after stimulation of the parabrachial-insular cortex (PB-IC) axis. It also examined whether the rewarding effects are naloxone-dependent. The results show that electrical stimulation of the CeA and external lateral parabrachial subnucleus (LPBe) induces consistent preference behaviors in a cPP task. However, subcutaneous administration of an opiate antagonist (naloxone; 4mg/ml/kg) blocked the rewarding effect of the parabrachial stimulation but not that of the amygdala stimulation. These results are interpreted in the context of multiple brain reward systems that appear to differ both anatomically and neurochemically, notably with respect to the opiate system. PMID:27173444

  8. ICCS 2009 User Guide for the International Database. Supplement 3: Variables Derived from the Survey Data

    Science.gov (United States)

    Brese, Falk; Jung, Michael; Mirazchiyski, Plamen; Schulz, Wolfram; Zuehlke, Olaf

    2011-01-01

    This supplement contains documentation on all the derived variables contained in the International Civic and Citizenship Education Study (ICCS) 2009 data files that are based on survey variables. These variables were used to report data in the ICCS 2009 international reports, and are made available as part of the ICCS 2009 International Database…

  9. Ghrelin Increases GABAergic Transmission and Interacts with Ethanol Actions in the Rat Central Nucleus of the Amygdala

    OpenAIRE

    Maureen T. Cruz; Herman, Melissa A.; Cote, Dawn M; Ryabinin, Andrey E.; Roberto, Marisa

    2012-01-01

    The neural circuitry that processes natural rewards converges with that engaged by addictive drugs. Because of this common neurocircuitry, drugs of abuse have been able to engage the hedonic mechanisms normally associated with the processing of natural rewards. Ghrelin is an orexigenic peptide that stimulates food intake by activating GHS-R1A receptors in the hypothalamus. However, ghrelin also activates GHS-R1A receptors on extrahypothalamic targets that mediate alcohol reward. The central n...

  10. Estrogen receptor beta activation prevents glucocorticoid receptor-dependent effects of the central nucleus of the amygdala on behavior and neuroendocrine function.

    Science.gov (United States)

    Weiser, Michael J; Foradori, Chad D; Handa, Robert J

    2010-06-01

    Neuropsychiatric disorders such as anxiety and depression have formidable economic and societal impacts. A dysregulation of the hypothalamo-pituitary-adrenal (HPA) axis leading to elevated endogenous glucocorticoid levels is often associated with such disorders. Chronically high glucocorticoid levels may act upon the central nucleus of the amygdala (CeA) to alter normally adaptive responses into those that are maladaptive and detrimental. In addition to glucocorticoids, other steroid hormones such as estradiol and androgens can also modify hormonal and behavioral responses to threatening stimuli. In particular, estrogen receptor beta (ERbeta) agonists have been shown to be anxiolytic. Consequently, these experiments addressed the hypothesis that the selective stimulation of glucocorticoid receptor (GR) in the CeA would increase anxiety-like behaviors and HPA axis reactivity to stress, and further, that an ERbeta agonist could modulate these effects. Young adult female Sprague-Dawley rats were ovariectomized and bilaterally implanted via stereotaxic surgery with a wax pellet containing the selective GR agonist RU28362 or a blank pellet, to a region just dorsal to the CeA. Four days later, animals were administered the ERbeta agonist S-DPN or vehicle (with four daily sc injections). Anxiety-type behaviors were measured using the elevated plus maze (EPM). Central RU28362 implants caused significantly higher anxiety-type behaviors in the EPM and greater plasma CORT levels than controls given a blank central implant. Moreover, S-DPN treated animals, regardless of type of central implant, displayed significantly lower anxiety-type behaviors and post-EPM plasma CORT levels than vehicle treated controls or vehicle treated animals implanted with RU28362. These results indicate that selective activation of GR within the CeA is anxiogenic, and peripheral administration of an ERbeta agonist can overcome this effect. These data suggest that estradiol signaling via ERbeta

  11. Inhibition of the amygdala central nucleus by stimulation of cerebellar output in rats: a putative mechanism for extinction of the conditioned fear response.

    Science.gov (United States)

    Magal, Ari; Mintz, Matti

    2014-11-01

    The amygdala and the cerebellum serve two distinctively different functions. The amygdala plays a role in the expression of emotional information, whereas the cerebellum is involved in the timing of discrete motor responses. Interaction between these two systems is the basis of the two-stage theory of learning, according to which an encounter with a challenging event triggers fast classical conditioning of fear-conditioned responses in the amygdala and slow conditioning of motor-conditioned responses in the cerebellum. A third stage was hypothesised when an apparent interaction between amygdala and cerebellar associative plasticity was observed: an adaptive rate of cerebellum-dependent motor-conditioned responses was associated with a decrease in amygdala-dependent fear-conditioned responses, and was interpreted as extinction of amygdala-related fear-conditioned responses by the cerebellar output. To explore this hypothesis, we mimicked some components of classical eyeblink conditioning in anesthetised rats by applying an aversive periorbital pulse as an unconditioned stimulus and a train of pulses to the cerebellar output nuclei as a cerebellar neuronal-conditioned response. The central amygdala multiple unit response to the periorbital pulse was measured with or without a preceding train to the cerebellar output nuclei. The results showed that activation of the cerebellar output nuclei prior to periorbital stimulation produced diverse patterns of inhibition of the amygdala response to the periorbital aversive stimulus, depending upon the nucleus stimulated, the laterality of the nucleus stimulated, and the stimulus interval used. These results provide a putative extinction mechanism of learned fear behavior, and could have implications for the treatment of pathologies involving abnormal fear responses by using motor training as therapy. PMID:25185877

  12. Quality Control, Testing, and Deployment Results in the NIF ICCS

    International Nuclear Information System (INIS)

    The strategy used to develop the NIF Integrated Computer Control System (ICCS) calls for incremental cycles of construction and formal test to deliver a total of 1 million lines of code. Each incremental release takes four to six months to implement specific functionality and culminates when offline tests conducted in the ICCS Integration and Test Facility verify functional, performance, and interface requirements. Tests are then repeated on line to confirm integrated operation in dedicated laser laboratories or ultimately in the NIF. Test incidents along with other change requests are recorded and tracked to closure by the software change control board (SCCB). Annual independent audits advise management on software process improvements. Extensive experience has been gained by integrating controls in the prototype laser preamplifier laboratory. The control system installed in the preamplifier lab contains five of the ten planned supervisory subsystems and seven of sixteen planned front-end processors (FEPs). Beam alignment, timing, diagnosis and laser pulse amplification up to 20 joules was tested through an automated series of shots. Other laboratories have provided integrated testing of six additional FEPs. Process measurements including earned-value, product size, and defect densities provide software project controls and generate confidence that the control system will be successfully deployed

  13. Quality Control, Testing and Deployment Results in NIF ICCS

    Science.gov (United States)

    Woodruff, John

    The strategy used to develop the NIF Integrated Computer Control System (ICCS) calls for incremental cycles of construction and formal test to deliver a total of 1 million lines of code. Each incremental release takes four to six months to implement specific functionality and culminates when offline tests conducted in the ICCS Integration and Test Facility verify functional, performance, and interface requirements. Tests are then repeated on line to confirm integrated operation in dedicated laser laboratories or ultimately in the NIF. Test incidents along with other change requests are recorded and tracked to closure by the software change control board (SCCB). Annual independent audits advise management on software process improvements. Extensive experience has been gained by integrating controls in the prototype laser preamplifier laboratory. The control system installed in the preamplifier lab contains five of the ten planned supervisory subsystems and seven of sixteen planned front-end processors (FEPs). Beam alignment, timing, diagnosis and laser pulse amplification up to 20 joules was tested through an automated series of shots. Other laboratories have provided integrated testing of six additional FEPs. Process measurements including earned-value, product size, and defect densities provide software project controls and generate confidence that the control system will be successfully deployed.

  14. Inhibition of CaMKIIα in the Central Nucleus of Amygdala Attenuates Fentanyl-Induced Hyperalgesia in Rats.

    Science.gov (United States)

    Li, Zhen; Li, Chenhong; Yin, Pingping; Wang, Zaijie Jim; Luo, Fang

    2016-10-01

    Opioid-induced hyperalgesia (OIH) is a less-studied phenomenon that has been reported in both preclinical and clinical studies. Although the underlying cause is not entirely understood, OIH is a real-life problem that affects millions of patients on a daily basis. Research has implicated the important contribution of Ca(2+)/calmodulin-dependent protein kinase IIα (CaMKIIα) to OIH at the level of spinal nociceptors. To expand our understanding of the entire brain circuitry driving OIH, in this study we investigated the role of CaMKIIα in the laterocapcular division of the central amygdala (CeLC), the conjunctive point between the spinal cord and rostro-ventral medulla. OIH was produced by repeated fentanyl administration in the rat. Correlating with the development of mechanical allodynia and thermal hyperalgesia, CaMKIIα activity was significantly elevated in the CeLC in OIH. In addition, the frequency and amplitude of spontaneous miniature excitatory postsynaptic currents (mEPSCs) in CeLC neurons were significantly increased in OIH. 2-[N-(2-hidroxyethyl)-N-(4-methoxy-benzenesulfonyl)]-amino-N-(4-chlorocinnamyl)-N-methylbenzylamine, a CaMKIIα inhibitor, dose dependently reversed sensory hypersensitivity, activation of CeLC CaMKIIα, and mEPSCs in OIH. Taken together, our data for the first time implicate a critical role of CeLC CaMKIIα in OIH. PMID:27451410

  15. Global features of nucleus-nucleus collisions in ultrarelativistic domain

    International Nuclear Information System (INIS)

    HIJING generator simulation of nucleus-nucleus collisions at ultrarelativistic energies is presented. It is shown that the global characteristics of nucleus-nucleus collisions, such as distribution of a charged multiplicity, total and electromagnetic transverse energy over pseudorapidity are rather sensitive to some predictions of models of high-exited nuclear medium formation, namely parton energy losses in dense nuclear matter. These losses result in appearance of a broad maximum in global variable distributions over pseudorapidity. The most profound of this effect occurs at central heavy ion collisions at LHC energy

  16. Cyrogenic aspects of the internally cooled, cabled superconductor (ICCS) for the 12-TESLA program

    International Nuclear Information System (INIS)

    The contribution of the ICCS/HFTF Test Coil program is described in terms of the understanding of supercritical helium thermodynamics in relation to ICCS stability. The helium pump module appears satisfactory for use in conjunction with the ICCS/HFTF Test Coil. High field tests of Airco Nb3Sn superconducting cables, encapsulated in stainless steel sheaths, show only slight reductions in critical current density from those of single wires. Magnetic pulse penetration of the sheath to produce detectable normal zones has also been demonstrated. Cryogenically compatible sheaths have been fabricated on a production basis. Prototypical terminations for the ICCS/HFTF Test Coil have been fabricated and should be tested shortly

  17. Precision measurement of ICCs of some pure E2 transitions for comparison with BRICC calculations

    International Nuclear Information System (INIS)

    There are specific problems to overcome in decay data analysis; in particular, difficulties can arise in accounting for internal conversion when the internal conversion of a gamma ray transition is significant. If there are no experimental ICCs available, theoretical ICCs have to be adopted, and the evaluator is faced with having to choose a value from a number of comparable theoretical approaches. Hence it is of paramount importance to have both very precise experimental ICCs and also to know the accuracy with which any theoretical ICC can be accepted to use

  18. Activation of corticotropin releasing factor-containing neurons in the rat central amygdala and bed nucleus of the stria terminalis following exposure to two different anxiogenic stressors.

    Science.gov (United States)

    Butler, Ryan K; Oliver, Elisabeth M; Sharko, Amanda C; Parilla-Carrero, Jeffrey; Kaigler, Kris F; Fadel, Jim R; Wilson, Marlene A

    2016-05-01

    Rats exposed to the odor of a predator or to the elevated plus maze (EPM) express unique unconditioned fear behaviors. The extended amygdala has previously been demonstrated to mediate the response to both predator odor and the EPM. We seek to determine if divergent amygdalar microcircuits are associated with the different behavioral responses. The current experiments compared activation of corticotropin-releasing factor (CRF)-containing neuronal populations in the central amygdala and bed nucleus of the stria terminalis (BNST) of rats exposed to either the EPM (5 min) versus home cage controls, or predator (ferret) odor versus butyric acid, or no odor (30 min). Sections of the brains were prepared for dual-labeled immunohistochemistry and counts of c-Fos co-localized with CRF were made in the centrolateral and centromedial amygdala (CLA and CMA) as well as the dorsolateral (dl), dorsomedial (dm), and ventral (v) BNST. Ferret odor-exposed rats displayed an increase in duration and a decrease in latency of defensive burying versus control rats. Exposure to both predator stress and EPM induced neuronal activation in the BNST, but not the central amygdala, and similar levels of neuronal activation were seen in both the high and low anxiety groups in the BNST after EPM exposure. Dual-labeled immunohistochemistry showed a significant increase in the percentage of CRF/c-Fos co-localization in the vBNST of ferret odor-exposed rats compared to control and butyric acid-exposed groups as well as EPM-exposed rats compared to home cage controls. In addition, an increase in the percentage of CRF-containing neurons co-localized with c-Fos was observed in the dmBNST after EPM exposure. No changes in co-localization of CRF with c-Fos was observed with these treatments in either the CLA or CMA. These results suggest that predator odor and EPM exposure activates CRF neurons in the BNST to a much greater extent than CRF neurons of the central amygdala, and indicates unconditioned

  19. Inhibition of corticotropin releasing factor expression in the central nucleus of the amygdala attenuates stress-induced behavioral and endocrine responses

    Directory of Open Access Journals (Sweden)

    PatrickJRonan

    2013-10-01

    Full Text Available Corticotropin releasing factor (CRF is a primary mediator of endocrine, autonomic and behavioral stress responses. Studies in both humans and animal models have implicated CRF in a wide-variety of psychiatric conditions including anxiety disorders such as post-traumatic stress disorder (PTSD, depression, sleep disorders and addiction among others. The central nucleus of the amygdala (CeA, a key limbic structure with one of the highest concentrations of CRF-producing cells outside of the hypothalamus, has been implicated in anxiety-like behavior and a number of stress-induced disorders. This study investigated the specific role of CRF in the CeA on both endocrine and behavioral responses to stress. We used RNA Interference (RNAi techniques to locally and specifically knockdown CRF expression in CeA. Behavior was assessed using the elevated plus maze (EPM and open field test (OF. Knocking down CRF expression in the CeA had no significant effect on measures of anxiety-like behavior in these tests. However, it did have an effect on grooming behavior, a CRF-induced behavior. Prior exposure to a stressor sensitized an amygdalar CRF effect on stress-induced HPA activation. In these stress-challenged animals silencing CRF in the CeA significantly attenuated corticosterone responses to a subsequent behavioral stressor. Thus, it appears that while CRF projecting from the CeA does not play a significant role in the expression stress-induced anxiety-like behaviors on the EPM and OF it does play a critical role in stress-induced HPA activation.

  20. ICCS 2009 User Guide for the International Database. Supplement 2: National Adaptations of International Questionnaires

    Science.gov (United States)

    Brese, Falk; Jung, Michael; Mirazchiyski, Plamen; Schulz, Wolfram; Zuehlke, Olaf

    2011-01-01

    This supplement describes national adaptations made to the international version of the International Civic and Citizenship Education Study (ICCS) 2009 questionnaires. This information provides users with a guide to evaluate the availability of internationally comparable data for use in secondary analyses involving the ICCS 2009 questionnaire…

  1. Progress in digital color workflow understanding in the International Color Consortium (ICC) Workflow WG

    Science.gov (United States)

    McCarthy, Ann

    2006-01-01

    The ICC Workflow WG serves as the bridge between ICC color management technologies and use of those technologies in real world color production applications. ICC color management is applicable to and is used in a wide range of color systems, from highly specialized digital cinema color special effects to high volume publications printing to home photography. The ICC Workflow WG works to align ICC technologies so that the color management needs of these diverse use case systems are addressed in an open, platform independent manner. This report provides a high level summary of the ICC Workflow WG objectives and work to date, focusing on the ways in which workflow can impact image quality and color systems performance. The 'ICC Workflow Primitives' and 'ICC Workflow Patterns and Dimensions' workflow models are covered in some detail. Consider the questions, "How much of dissatisfaction with color management today is the result of 'the wrong color transformation at the wrong time' and 'I can't get to the right conversion at the right point in my work process'?" Put another way, consider how image quality through a workflow can be negatively affected when the coordination and control level of the color management system is not sufficient.

  2. Emergence of tuning to natural stimulus statistics along the central auditory pathway.

    Directory of Open Access Journals (Sweden)

    Jose A Garcia-Lazaro

    Full Text Available We have previously shown that neurons in primary auditory cortex (A1 of anaesthetized (ketamine/medetomidine ferrets respond more strongly and reliably to dynamic stimuli whose statistics follow "natural" 1/f dynamics than to stimuli exhibiting pitch and amplitude modulations that are faster (1/f(0.5 or slower (1/f(2 than 1/f. To investigate where along the central auditory pathway this 1/f-modulation tuning arises, we have now characterized responses of neurons in the central nucleus of the inferior colliculus (ICC and the ventral division of the mediate geniculate nucleus of the thalamus (MGV to 1/f(γ distributed stimuli with γ varying between 0.5 and 2.8. We found that, while the great majority of neurons recorded from the ICC showed a strong preference for the most rapidly varying (1/f(0.5 distributed stimuli, responses from MGV neurons did not exhibit marked or systematic preferences for any particular γ exponent. Only in A1 did a majority of neurons respond with higher firing rates to stimuli in which γ takes values near 1. These results indicate that 1/f tuning emerges at forebrain levels of the ascending auditory pathway.

  3. ICC density predicts bacterial overgrowth in a rat model of post-infectious IBS

    Institute of Scientific and Technical Information of China (English)

    Sam-Ryong; Jee; Walter; Morales; Kimberly; Low; Christopher; Chang; Amy; Zhu; Venkata; Pokkunuri; Soumya; Chatterjee; Edy; Soffer; Jeffrey; L; Conklin; Mark; Pimentel

    2010-01-01

    AIM:To investigate the interstitial cells of Cajal(ICC) number using a new rat model.METHODS:Sprague-Dawley rats were assigned to two groups.The first group received gavage with Campylobacter jejuni(C.jejuni) 81-176.The second group was gavaged with placebo.Three months after clearance of Campylobacter from the stool,precise segments of duodenum,jejunum,and ileum were ligated in self-contained loops of bowel that were preserved in anaerobic bags.Deep muscular plexus ICC(DMP-ICC) were quantified by two blind...

  4. ICC density predicts bacterial overgrowth in a rat model of post-infectious IBS

    OpenAIRE

    Sam-Ryong Jee, Walter Morales, Kimberly Low, Christopher Chang, Amy Zhu, Venkata Pokkunuri, Soumya Chatterjee, Edy Soffer, Jeffrey L Conklin, Mark Pimentel

    2010-01-01

    AIM: To investigate the interstitial cells of Cajal (ICC) number using a new rat model.METHODS: Sprague-Dawley rats were assigned to two groups. The first group received gavage with Campylobacter jejuni (C. jejuni) 81-176. The second group was gavaged with placebo. Three months after clearance of Campylobacter from the stool, precise segments of duodenum, jejunum, and ileum were ligated in self-contained loops of bowel that were preserved in anaerobic bags. Deep muscular plexus ICC (DMP-ICC) ...

  5. 40 CFR 180.1294 - Trichoderma asperellum strain ICC 012; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Trichoderma asperellum strain ICC 012... RESIDUES IN FOOD Exemptions From Tolerances § 180.1294 Trichoderma asperellum strain ICC 012; exemption from the requirement of a tolerance. Trichoderma asperellum strain ICC 012 is exempted from...

  6. 40 CFR 180.1293 - Trichoderma gamsii strain ICC 080; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Trichoderma gamsii strain ICC 080... RESIDUES IN FOOD Exemptions From Tolerances § 180.1293 Trichoderma gamsii strain ICC 080; exemption from the requirement of a tolerance. Trichoderma gamsii strain ICC 080 is exempted from the requirement...

  7. Develop and test an Internally Cooled, Cabled Superconductor (ICCS) for large scale MHD magnets: Analysis report

    Science.gov (United States)

    Hatch, A. M.; Marston, P. G.; Tarrh, J. M.; Becker, H.; Dawson, A. M.; Minervini, J. V.

    1986-01-01

    A three-year program to develop and test an internally-cooled cabled superconductor (ICCS) for large-scale MHD magnets is being performed by MIT for the Pittsburgh Energy Technology Center (PETC) under contract DE-AC22-84PC70512. Included in this report are electromagnetic, thermodynamic, structural, protection, and systems analyses, completed as required to substantiate the preliminary conductor design requirements definition and the associated preconceptual magnet design developed in Task 1. Copper-stabilized NbTi superconductor was selected at the outset as being most suitable for the application. The analysis necessary to substantiate the preconceptual MHD magnet design is complete, including field and force calculations, preliminary structural analysis, thermodynamic (cryogenic) analysis, and the analysis of the magnet electrical and protective systems. A significant result of the field analysis is the determination that maximum fields to which the conductor is exposed in the magnet are considerably higher than originally expected. Changes were made to produce a revised design in which the maximum field is 6.9T (53% above central field) and adequate stability is ensured. Analysis necessary to substantiate a preliminary conductor design requirement definition for full-scale conductor has been completed except that further work is required to establish maximum allowable internal flow resistance and maximum length between vents. Procedures for accomplishing these analyses have already been developed at MIT and by other contractors.

  8. Neurons of human nucleus accumbens

    Directory of Open Access Journals (Sweden)

    Sazdanović Maja

    2011-01-01

    Full Text Available Background/Aim. Nucleus accumbens is a part of the ventral striatum also known as a drug active brain region, especially related with drug addiction. The aim of the study was to investigate the Golgi morphology of the nucleus accumbens neurons. Methods. The study was performed on the frontal and sagittal sections of 15 human brains by the Golgi Kopsch method. We classified neurons in the human nucleus accumbens according to their morphology and size into four types: type I - fusiform neurons; type II - fusiform neurons with lateral dendrite, arising from a part of the cell body; type III - pyramidal-like neuron; type IV - multipolar neuron. The medium spiny neurons, which are mostly noted regarding to the drug addictive conditions of the brain, correspond to the type IV - multipolar neurons. Results. Two regions of human nucleus accumbens could be clearly recognized on Nissl and Golgi preparations each containing different predominant neuronal types. Central part of nucleus accumbens, core region, has a low density of impregnated neurons with predominant type III, pyramidal-like neurons, with spines on secondary branches and rare type IV, multipolar neurons. Contrary to the core, peripheral region, shell of nucleus, has a high density of impregnated neurons predominantly contained of type I and type IV - multipolar neurons, which all are rich in spines on secondary and tertiary dendritic branches. Conclusion. Our results indicate great morphological variability of human nucleus accumbens neurons. This requires further investigations and clarifying clinical significance of this important brain region.

  9. Angular characteristics of pion-nucleus interaction

    International Nuclear Information System (INIS)

    In the present paper pion-nucleus interactions have been studied using nuclear emulsion technique. The investigation of these interactions is expected to provide some very useful information about the multiparticle production mechanism. Nuclear emulsion is a material which memorizes the tracks of charged particles. When a primary particle collides with a nucleus, it may interact with the nucleons of the target nucleus in two ways. In the first case, independent reactions may take place between the incident particle and the nucleons present in the target nucleus. Secondly the primary particle may interact coherently with the various nucleons of the target nucleus and the secondary particles are produced. Angular distribution of charged secondaries produced in these interactions has been studied for central collision events. Different workers have used different criterion for the selection of central collisions. We analysed the events with high shower particle multiplicity i.e., Ns ≥ 28 and call them as central collision events

  10. Large philipsite crystal as ferromanganese nodule nucleus

    Digital Repository Service at National Institute of Oceanography (India)

    Ghosh, A.K.; Mukhopadhyay, R.

    We report here the occurrence of, to date, the largest (21 x 10 x 8 mm) phillipsite crystal forming the nucleus of a diagenetically formed ferromanganese nodule from the Central Indian Ocean Basin (CIOB). Assuming an average rate of ferromanganese...

  11. A Brief Discussion on the Key Factors of Developing and Implementing College Student's ICC

    Institute of Scientific and Technical Information of China (English)

    YANG Xi; WANG Yan-ru

    2015-01-01

    Language and culture are interrelated with each other, to learn a foreign language is not only about learning language it⁃self, but achieving a mutual understanding and appreciating of other cultures. The need for the people of intercultural communica⁃tive competence (ICC) in various work fields is consistently increasing. The development and implementation of intercultural com⁃municative competence has become the major goal of college English teaching. This paper mainly discusses the main factors in de⁃veloping and implementing ICC to find out their possible benefits and constrains in order to give some suggestions for the further development of Chinese college English teachers.

  12. Differential modulation of arcuate nucleus and mesolimbic gene expression levels by central leptin in rats on short-term high-fat high-sugar diet

    NARCIS (Netherlands)

    van den Heuvel, José K; Eggels, Leslie; Fliers, Eric; Kalsbeek, A.; Adan, Roger A H; la Fleur, Susanne E

    2014-01-01

    OBJECTIVE: Leptin resistance is a common hallmark of obesity. Rats on a free-choice high-fat high-sugar (fcHFHS) diet are resistant to peripherally administered leptin. The aim of this study was to investigate feeding responses to central leptin as well as the associated changes in mRNA levels in hy

  13. La evaluación de las competencias culturales: Validación del inventario ICC

    Directory of Open Access Journals (Sweden)

    ALEJANDRO CASTRO SOLANO

    2012-01-01

    La versión final del ICC consta de cinco dimensiones, tres correspondientes al IAC: Apertura a Experiencias Nuevas, Autonomia e Independencia, Aceptación de la Diversidad Cultural, y dos que se incluyen en este estudio: Inestabilidad Emocional y Vinculos. Participaron 334 sujetos (150 hombres y 184 mujeres que tenian en promedio 33.86 años (DE ~ 13.84 Yresidian en la Ciudad Autónoma de Buenos Aires (n ~ 228, 68% Yen el Conurbano Bonaerense (n ~ 106, 32%. Los resultados obtenidos permiten afirmar que el ICC presenta propiedades psicométricas satisfactorias (fiabilidad y validez. En cuanto a su validez interna, los análisis pudieron verificar que el ICC estaba compuesto por cinco dimensiones. En cuanto a su validez externa el ICC presenta evidencias de validez convergente con el BFI (Big Five Inventory, con el CAO (Cuestionario de Apertura al Otro y con el SWLS (Satisfacción Con La Vida.

  14. An International Perspective on Civic Participation in Irish Post-Primary Schools: Results from ICCS

    Science.gov (United States)

    Cosgrove, Jude; Gilleece, Lorraine

    2012-01-01

    Ireland was one of the 38 countries/education systems that participated in the International Civic and Citizenship Education Study (ICCS) in 2009. This is the first international comparative study in this area in which Ireland has participated since 1971. The study measured the civic knowledge of 14-year-olds and their attitudes towards, and…

  15. The Modes of Liability at the ICC: The Labels that Don't Always Stick

    DEFF Research Database (Denmark)

    Aksenova, Marina

    2015-01-01

    The article critically analyses recent developments in the jurisprudence of the International Criminal Court. In particular, it scrutinises two convictions rendered by the Court to the date with the view of assessing the viability of the modes of liability employed by the ICC. The argument is that...

  16. NMDA Receptor Antagonism in the Lateral/Basolateral but Not Central Nucleus of the Amygdala Prevents the Induction of Facilitated Learning in Response to Stress

    OpenAIRE

    Shors, Tracey J.; Mathew, Pramod R.

    1998-01-01

    Exposure to an acute stressful event facilitates classical eye-blink conditioning in the male rat. The facilitation persists for days after the stressor and its induction is prevented by antagonism of the N-methyl-d-aspartate (NMDA) type of glutamate receptor. To determine whether NMDA receptor antagonists prevent the facilitated conditioning by activity in the amygdala, a competitive antagonist, AP5, was injected bilaterally into the lateral/basolateral versus central nuclei of the amygdala....

  17. ICCS 2009 European Report: Civic Knowledge, Attitudes, and Engagement among Lower-Secondary Students in 24 European Countries

    Science.gov (United States)

    Kerr, David; Sturman, Linda; Schulz, Wolfram; Burge, Bethan

    2010-01-01

    The International Civic and Citizenship Education Study (ICCS) studied the ways in which countries prepare their young people to undertake their roles as citizens. ICCS was based on the premise that preparing students for citizenship involves helping them develop relevant knowledge and understanding and form positive attitudes toward being a…

  18. ICCS 2009 International Report: Civic Knowledge, Attitudes, and Engagement among Lower-Secondary School Students in 38 Countries

    Science.gov (United States)

    Schulz, Wolfram; Ainley, John; Fraillon, Julian; Kerr, David; Losito, Bruno

    2010-01-01

    The International Civic and Citizenship Education Study (ICCS) studied the ways in which countries prepare their young people to undertake their roles as citizens. ICCS was based on the premise that preparing students for citizenship roles involves helping them develop relevant knowledge and understanding and form positive attitudes toward being a…

  19. 78 FR 73914 - In the Matter of ICC Worldwide, Inc., Innova Pure Water, Inc., Paladin Holdings, Inc., Performing...

    Science.gov (United States)

    2013-12-09

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION In the Matter of ICC Worldwide, Inc., Innova Pure Water, Inc., Paladin Holdings, Inc., Performing... securities of ICC Worldwide, Inc. because it has not filed any periodic reports since the period ended...

  20. ICCS 2009 Asian Report: Civic Knowledge and Attitudes among Lower-Secondary Students in Five Asian Countries

    Science.gov (United States)

    Fraillon, Julian; Schulz, Wolfram; Ainley, John

    2012-01-01

    This report presents findings from the Asian regional module of the International Civic and Citizenship Education Study (ICCS), sponsored by the International Association for the Evaluation of Educational Achievement (IEA). ICCS studied the ways in which young people in lower-secondary schools are prepared to undertake their roles as citizens.…

  1. Study of high energy nucleus nucleus collisions

    International Nuclear Information System (INIS)

    The CERN experiment WA80 studies ultrarelativistic heavy ion collisions by calorimetry and charged particle measurements over a large fraction of 4π. Here I want to concentrate on a closer study of nucleus nucleus collisions and recent results from the lead glass spectrometer Saphir. 6 refs., 5 figs

  2. Accelerated electrochemical test of 14Kh17N2 steel susceptibility to ICC

    International Nuclear Information System (INIS)

    Description of the accelerated electrochemical technique used to determine susceptibility 14Kh17N2 steel of ferrite-martensite type to intercrystallite corrosion under the drop of electrolyte, is given. Convergence of the results obtained due to accelerated techniques with those of tests using the All-Union Standards 6032-84 constitutes 95%. These results demonstrate possibility to use data of the accelerated techniques for rapid estimation of susceptibility to ICC of martensite-ferrite steel-14Kh17N2

  3. Nuorten yhteiskunnalliset tiedot, osallistuminen ja asenteet : kansainvälisen ICCS 2009 -tutkimuksen ensituloksia

    OpenAIRE

    Suoninen, Annikka; Kupari, Pekka; Törmäkangas, Kari

    2010-01-01

    Kansainvälisen ICCS-tutkimuksen tavoitteena on selvittää, millaiset valmiudet nuorilla on toimia ja osallistua aktiivisina kansalaisina 21. vuosisadan yhteiskunnassa. Tutkimukseen osallistui 38 maata eri puolilta maailmaa. Julkaisu kertoo tutkimuksen ensimmäisistä tuloksista. Millaiset ovat peruskoulun 8.-luokkalaisten yhteiskunnalliset tiedot ja miten ne ovat muuttuneet 10 vuoden aikana? Kiinnostavatko politiikka ja yhteiskunnalliset asiat nuoria? Millaista on nuorten osallistuminen koul...

  4. Developing ICC Profile Using Gray Level Control In Offset Printing Process

    OpenAIRE

    Dilawari, Jaswinder Singh; Khanna, Ravinder

    2012-01-01

    In prepress department RGB image has to be converted to CMYK image. To control that amount of black, cyan, magenta and yellow has to be controlled by using color separation method. Graycolor separation method is selected to control the amounts of these colors because it increase the quality of printing also. A single printer used for printing the same image on different paper also results in different printed images. To remove this problem a different ICC profile based on gray level control i...

  5. Quality evaluation of current ICC-profile generation tools for CMYK-output devices

    Science.gov (United States)

    Jung, Eggert; Buering, Hendrik; Herzog, Patrick G.

    2002-06-01

    ICC-color Management tools claim to give both accurate and consistent results. However, using these tools of distinct manufacturers, different results are likely to occur even if the same parameters are given. Obviously the manufacturers do not focus on the same criteria doing their optimizations, which leads to the fact that each tool has its own strengths and weaknesses. In this study, new methods for comparing ColorManagement tools were evaluated, and with these methods, ICC profiles generated by five CM tools of current leaders on the market were investigated in order to point out their weaknesses and strengths. In addition, the influence of using various ColorMatchingModules (CMM) was tested. For the generation of each ICC profile, the same measurements (ISO 12642 equals ANSI IT8. 7/3 target of Iris InkjetPrinter) were used. Since the standardized ISO 12642 file format, in which the measurement data are stored, was not accepted by each of the tools, the data-file had to be converted to proprietary formats. The investigated quality aspects were accuracy, consistency and smoothness, with ΔEab2 and ΔE943 taken as the criteria. For each aspect, performance was visualized by mapping the ΔE values to pseudo colors, giving a very intuitive view on the investigated subject. Results showed that ColorManagement tools indeed achieved good color fidelity, especially if generated as large profiles.

  6. Encoding of the amplitude modulation of pulsatile electrical stimulation in the feline cochlear nucleus by neurons in the inferior colliculus; effects of stimulus pulse rate

    Science.gov (United States)

    McCreery, Douglas; Han, Martin; Pikov, Victor; Yadav, Kamal; Pannu, Satinderpall

    2013-10-01

    Objectives. Persons without a functional auditory nerve cannot benefit from cochlear implants, but some hearing can be restored by an auditory brainstem implant (ABI) with stimulating electrodes implanted on the surface of the cochlear nucleus (CN). Most users benefit from their ABI, but speech recognition tends to be poorer than for users of cochlear implants. Psychophysical studies suggest that poor modulation detection may contribute to the limited performance of ABI users. In a cat model, we determined how the pulse rate of the electrical stimulus applied within or on the CN affects temporal and rate encoding of amplitude modulation (AM) by neurons in the central nucleus of the inferior colliculus (ICC). Approach. Stimulating microelectrodes were implanted chronically in and on the cats' CN, and multi-site recording microelectrodes were implanted chronically into the ICC. Encoding of AM pulse trains by neurons in the ICC was characterized as vector strength (VS), the synchrony of neural activity with the AM, and as the mean rate of neuronal action potentials (neuronal spike rate (NSR)). Main results. For intranuclear microstimulation, encoding of AM as VS was up to 3 dB greater when stimulus pulse rate was increased from 250 to 500 pps, but only for neuronal units with low best acoustic frequencies, and when the electrical stimulation was modulated at low frequencies (10-20 Hz). For stimulation on the surface of the CN, VS was similar at 250 and 500 pps, and the dynamic range of the VS was reduced for pulse rates greater than 250 pps. Modulation depth was encoded strongly as VS when the maximum stimulus amplitude was held constant across a range of modulation depth. This ‘constant maximum’ protocol allows enhancement of modulation depth while preserving overall dynamic range. However, modulation depth was not encoded as strongly as NSR. Significance. The findings have implications for improved sound processors for present and future ABIs. The performance of

  7. An International Perspective on Active Citizenship among Lower Secondary Students. Concepts and Measures Developed for the IEA Civic and Citizenship Education Study (ICCS)

    Science.gov (United States)

    Schulz, Wolfram

    2007-01-01

    The new IEA "International Civic and Citizenship Education Study" (ICCS) will investigate the extent to which young people are prepared to undertake their roles as citizens across a range of countries. ICCS will survey 13-to-14-year old students in over 30 countries in the year 2009. The ICCS outcome data will be obtained from representative…

  8. Decrease and conquer: Phacoemulsification technique for hard nucleus cataracts.

    Science.gov (United States)

    Kim, Hong Kyun

    2009-10-01

    I describe a technique to improve the control and safety of phacoemulsification during hard nucleus cataract surgery. Whereas the goal of the conventional nucleofractis technique is complete fragmentation of the lens, the technique aims to separate the endonuclear core from the epinucleus. This is done in 3 steps: circumferential disassembly, decreasing the central nucleus volume, and conquering the remnant. The technique offers safer and more effective phacoemulsification in patients with hard nucleus cataracts. PMID:19781457

  9. The ultrastructural properties of CGRP-like immunoreactive synapses in the central nucleus of amygdala%中央杏仁核内 CGRP 能阳性突触的超微结构研究

    Institute of Scientific and Technical Information of China (English)

    鲁亚成; 田菲; 李云庆; 董玉琳

    2012-01-01

    Objective: To observe synaptic ultrastructure of calcitonin-gene-related peptide (CGRP)-like immunoreactive (LI) axonal terminals in the central nucleus of amygdala ( CeA). Methods; Immunofluorescence and pre-embedding electronic microscopy were employed to detect the classification and structural features of synapses made by CGRP-LI axonal terminals in the CeA. Results: CGRP-LI terminals were observed to make synapses on the soma of neurons, dendritic shafts and spines. Almost all the axo-soma synapses were symmetrical; However, most of the axo-dendritic shaft and axo-spine synapses were asymmetrical. In all asymmetrical synapses, the ratio of axo-dendritic shaft synapses were 84.9% , and axo-spine synapses 15. 1%. The average length of postsynaptic density (PSD) of axo-dendritic shaft synapses was 790.77 ±313. 55 nm, whereas of axo-spine synapses 723. 34 ±357. 20 nm. There was no significant difference of PSD length between two types of synapses. Conclusion: The CGRP-LI axo-dendritic shaft synapses play important roles in the transmission of nociception and pain-related abnormal emotional responses.%目的:观察降钙素基因相关肽(calcitonin-gene-related peptide,CGRP)样阳性终末在中央杏仁核(central nucleus of amygdala,CeA)内形成的突触的超微结构.方法:应用免疫荧光组织化学和包埋前免疫电镜等方法,观察CGRP样阳性终末在CeA内所形成的突触分布形式及结构特点.结果:CGRP样阳性终末在中央杏仁核内可以与细胞体、树突干和树突棘等结构形成突触;轴-体突触几乎全为对称性突触,而轴-树突触和轴-棘突触则多为非对称性突触.在所有的非对称性突触里,轴-树突触占84.9%,而轴-棘突触占15.1%.CGRP样阳性轴-树的突触后致密带的平均长度为(790.77±313.55)nm,而轴-棘突触的突触后致密带的平均长度为(723.34±357.20)nm,两者之间没有显著性差异.结论:CGPR样阳性的兴奋性突触尤其是轴-树

  10. Develop and test an Internally Cooled, Cabled Superconductor (ICCS) for large scale MHD magnets

    Science.gov (United States)

    Marston, P. G.; Hale, J. R.; Dawson, A. M.

    1990-04-01

    The work included four principal tasks: (1) development of a design requirements definition for a retrofit MHD magnet system; (2) analysis of an internally cooled, cabled superconductor (ICCS) to use in that design; (3) design of an experiment to test a subscale version of that conductor, which is a NbTi, copper stabilized superconductor; and (4) proof-of-concept testing of the conductor. The program was carried forth through the third task with very successful development and test of a conventional ICCS conductor with 27 multifilamentary copper-superconductor composite strands and a new concept conductor in which, in each triplet, two strands were pure copper and the third strand was a multifilamentary composite. In reviewing the magnet design and the premises for the conductor design it became obvious that an extra barrier might be highly effective in enhancing magnet stability and protection. This concept was developed and a sample conductor manufactured and tested in comparison with an identical conductor lacking such an additional barrier. Results of these conductor tests confirm the potential value of such a barrier. Since the work of tasks 1 through 3 has been reported in detail in quarterly and semiannual reports, as well as in special reports prepared throughout the course of this project, this report reviews early work briefly and then discusses this last phase in great detail.

  11. Search for ICC anomalies in nuclear transitions of 115In, 117Sn and 125Te

    International Nuclear Information System (INIS)

    One measured αC internal conversion factors in K-shell of 35 keV energy M1-transition in 115In nucleus, of M4-transitions of γ156.0 keV in 117Sn nucleus and of γ109 keV in 125Te nucleus. One derived αC=8.74+-0.09 for M1-transition in 115In, αC=30.8+-0.6 for 117Sn and αC=181.3+-3.6 for 125Te

  12. Photon Exchange in Nucleus-Nucleus Collisions

    OpenAIRE

    Bertulani, Carlos A.

    2002-01-01

    The strong electromagnetic fields in peripheral heavy ion collisions give rise to photon-photon and photon-nucleus interactions. I present a general survey of the photon-photon and photon-hadron physics accessible in these collisions. Among these processes I discuss the nuclear fragmentation through the excitation of giant resonances, the Coulomb dissociation method for application in nuclear astrophysics, and the production of particles.

  13. Uncovering the nucleus candidate for NGC 253

    CERN Document Server

    Günthardt, G I; Camperi, J A; Díaz, R J; Gomez, P L; Bosch, G; Schirmer, M

    2015-01-01

    NGC253 is the nearest spiral galaxy with a nuclear starburst which becomes the best candidate to study the relationship between starburst and AGN activity. However, this central region is veiled by large amounts of dust, and it has been so far unclear which is the true dynamical nucleus. The near infrared spectroscopy could be advantageous in order to shed light on the true nucleus identity. Using Flamingos-2 at Gemini South we have taken deep K-band spectra along the major axis and through the brightest infrared source. We present evidence showing that the brightest near infrared and mid infrared source in the central region, already known as radio source TH7 and so far considered just a stellar supercluster, in fact, presents various symptoms of a genuine galactic nucleus. Therefore, it should be considered a valid nucleus candidate. It is the most massive compact infrared object in the central region, located at 2.0" of the symmetry center of the galactic bar. Moreover, our data indicate that this object i...

  14. Internally cooled cable superconductor (ICCS) for TF and PF coils of FED

    International Nuclear Information System (INIS)

    Internally Cooled Cable Superconductor (ICCS) concepts developed for TF and PF coils of FED are described. The TF coil conductor design is based on an ICCS successfully used in a small test magnet at ORNL. The conductor consists of triplets of NbTi strands loosely packed in a stainless steel conduit similar to the Westinghouse LCP coil. The operating current for the conductor is 25.5 kA at 10 T and 3.1 K. The conductor is co-wound with a stainless steel C-shaped channel to provide a direct load path to the coil case for the accumulated magnetic loads in the winding. The strand diameter in the conductor is optimized to reduce the eddy current losses. The nuclear heating in the winding is the most dominant heat load. In order to remove these heat loads due to nuclear heating and ac losses in the winding, it is necessary to lower the inlet temperature of helium to 2.2 K. The conductor has a thermal capacity of about 200 mJ/cc, which provides a comfortable stability margin under the operating conditions. The PF conductor is similar to the TF conductor, but it is modified to meet the requirements of the PF coils. For this conductor, the superconducting filament diameter has been reduced and cupro-nickel barrier is provided between adjacent filaments for reducing the hyteresis and coupling ac losses, respectively, under relatively higher pulsed fields. The conductor is designed to carry 21.3 kA at 8 T and 4.5 K

  15. Integrating the Intercultural Communicative Competence (ICC) in a Foreign Language Program: Faculty Considerations upon Leaving the Haven of Native Speakership

    Science.gov (United States)

    Dimas, Héctor Manuel Serna

    2016-01-01

    This action research study presents the perspectives of two language faculty who integrated the principles of the Intercultural Communicative Competence (ICC) model in their teaching. The professors shared their understanding of intercultural communicative competence through a learning log. These reflections were mainly about the challenged notion…

  16. ICCS 2009 Latin American Report: Civic Knowledge and Attitudes among Lower-Secondary Students in Six Latin American Countries

    Science.gov (United States)

    Schulz, Wolfram; Ainley, John; Friedman, Tim; Lietz, Petra

    2011-01-01

    The International Civic and Citizenship Education Study (ICCS) focused on the ways in which young people are prepared to undertake their roles as citizens. Preparing students for citizenship involves developing relevant knowledge and understanding as well as encouraging the formation of positive attitudes toward being a citizen. Descriptions of…

  17. Nucleus-Nucleus Bremsstrahlung from Ultrarelativistic Collisions

    OpenAIRE

    Jeon, Sangyong; Kapusta, Joseph; Chikanian, Alexei; Sandweiss, Jack

    1998-01-01

    The bremsstrahlung produced when heavy nuclei collide is estimated for central collisions at the Relativistic Heavy Ion Collider. Soft photons can be used to infer the rapidity distribution of the outgoing charge. An experimental design is outlined.

  18. Status of the National Ignition Facility Integrated Computer Control System (ICCS) on the Path to Ignition

    International Nuclear Information System (INIS)

    The National Ignition Facility (NIF) at the Lawrence Livermore National Laboratory is a stadium-sized facility under construction that will contain a 192-beam, 1.8-Megajoule, 500-Terawatt, ultraviolet laser system together with a 10-meter diameter target chamber with room for multiple experimental diagnostics. NIF is the world's largest and most energetic laser experimental system, providing a scientific center to study inertial confinement fusion (ICF) and matter at extreme energy densities and pressures. NIF's laser beams are designed to compress fusion targets to conditions required for thermonuclear burn, liberating more energy than required to initiate the fusion reactions. NIF is comprised of 24 independent bundles of 8 beams each using laser hardware that is modularized into more than 6,000 line replaceable units such as optical assemblies, laser amplifiers, and multifunction sensor packages containing 60,000 control and diagnostic points. NIF is operated by the large-scale Integrated Computer Control System (ICCS) in an architecture partitioned by bundle and distributed among over 800 front-end processors and 50 supervisory servers. NIF's automated control subsystems are built from a common object-oriented software framework based on CORBA distribution that deploys the software across the computer network and achieves interoperation between different languages and target architectures. A shot automation framework has been deployed during the past year to orchestrate and automate shots performed at the NIF using the ICCS. In December 2006, a full cluster of 48 beams of NIF was fired simultaneously, demonstrating that the independent bundle control system will scale to full scale of 192 beams. At present, 72 beams have been commissioned and have demonstrated 1.4-Megajoule capability of infrared light. During the next two years, the control system will be expanded to include automation of target area systems including final optics, target positioners and

  19. Status of the National Ignition Facility Integrated Computer Control System (ICCS) on the path to ignition

    International Nuclear Information System (INIS)

    The National Ignition Facility (NIF) at the Lawrence Livermore National Laboratory is a stadium-sized facility under construction that will contain a 192-beam, 1.8-MJ, 500-TW, ultraviolet laser system together with a 10-m diameter target chamber with room for multiple experimental diagnostics. NIF is the world's largest and most energetic laser experimental system, providing a scientific center to study inertial confinement fusion (ICF) and matter at extreme energy densities and pressures. NIF's laser beams are designed to compress fusion targets to conditions required for thermonuclear burn, liberating more energy than required to initiate the fusion reactions. NIF is comprised of 24 independent bundles of eight beams each using laser hardware that is modularized into more than 6000 line replaceable units such as optical assemblies, laser amplifiers, and multi-function sensor packages containing 60,000 control and diagnostic points. NIF is operated by the large-scale Integrated Computer Control System (ICCS) in an architecture partitioned by bundle and distributed among over 800 front-end processors and 50 supervisory servers. NIF's automated control subsystems are built from a common object-oriented software framework based on CORBA distribution that deploys the software across the computer network and achieves interoperation between different languages and target architectures. A shot automation framework has been deployed during the past year to orchestrate and automate shots performed at the NIF using the ICCS. In December 2006, a full cluster of 48 beams of NIF was fired simultaneously, demonstrating that the independent bundle control system will scale to full scale of 192 beams. At present, 72 beams have been commissioned and have demonstrated 1.4-MJ capability of infrared light. During the next 2 years, the control system will be expanded in preparation for project completion in 2009 to include automation of target area systems including final optics

  20. ICC resistance of thin-walled tubes of super low carbon steel Kh17N14M3, alloyed with nitrogen

    International Nuclear Information System (INIS)

    The tendency to intercrystallite corrosion (ICC) in the range of 400-750 deg CV and 1-1000 h of thin-walled (0.3 mm) tubes of steel Kh17N14M3 was studied. Electrochemical investigations confirmed high ICC resistance of the tubes from particularly low-carbon experimental steels

  1. Nucleus Driven Electronic Pulsation

    CERN Document Server

    Ludwig, H; Xue, S -S

    2014-01-01

    We derive and solve by the spectral method the equations for a neutral system of ultra-relativistic electrons that are compressed to the radius of the nucleus and subject to a driving force. This driving force can be thought of as originating from a nuclear breathing mode, a possibility we discuss in detail.

  2. "We ourselves, we are part of the functioning": the ICC, victims, and civil society in the Central African Republic

    NARCIS (Netherlands)

    M. Glasius

    2009-01-01

    As a new justice institution, the International Criminal Court needs to gain legitimacy not just with states, but also in civil society, both at the global level and in the societies in which it intervenes. This article, based on interviews, NGO documents, newspaper articles, and participatory obser

  3. Enhancement of φ Mesons in Relativistic Nucleus-Nucleus Collisions

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The фmeson production in relativistic nucleus-nucleus collisions is investigated systematically usinga hadron-string cascade model LUCIAE. Within the framework of the model and relying on the collective

  4. High energy nucleus--nucleus studies at the Berkeley Bevalac. [Survey

    Energy Technology Data Exchange (ETDEWEB)

    Schroeder, L.S.

    1976-09-01

    A survey of high-energy nucleus--nucleus experiments performed at the Berkeley Bevalac Facility is presented. Experimental results are divided into the general areas of peripheral and central collisions. Results on projectile and target fragmentation, total cross-section measurements, pion and photon production, and charged-particle multiplicities are stressed. Recently, there have been theoretical predictions concerning the possibility of observing new phenomena such as shock waves, pion condensates, or collapsed nuclear matter. Existing data relevant to some of these speculations are discussed. A brief discussion of future developments with high-energy nuclear beams is also presented. 27 figures, 1 table.

  5. Fluctuations and intermittency in high energy nucleus-nucleus collisions

    International Nuclear Information System (INIS)

    Fluctuations of the particle densities in semi-central collisions of 16O, 28Si and 32S nuclei with heavy components of nuclear emulsion at different primary energies are studied. Various methods of data analysis have been used, ranging from the examination of the structure in individual events, to the study of the average factorial moments and conventional correlation functions. Emphasis is put on the analysis of the average factorial moments which appear to be the most efficient tool in searching for dynamical fluctuations. Unquestionable evidence for non-statistical fluctuations is found in 16O and 32S interactions with Ag/Br targets at 200 GeV/nucleon. Specifically, I observe larger deviations of individual pseudorapidity distributions from a smooth spectrum and more frequent occurrence of narrow spikes than expected from Monte Carlo simulations based on independent emission of secondary particles. Clear intermittency signals are found in pseudorapidity and azimuthal angle distributions. Intermittency effect is also observed in two dimensions, where it has turned out to be stronger and cleaner than in one-dimensional distributions. Multiplicity distributions in the restricted phase space domains are well described by the negative binomial formula and consequently I find that factorial moments can be equivalently obtained from the parameters of the negative binomial fits. On the other hand investigation of the two-particle correlation functions in pseudorapidity provides no supporting evidence for pronounced non-statistical correlations. The occurrence of large particle-density fluctuations is expected in the presence of phase transition in ultrarelativistic nuclear collisions. Even though the obtained results can not be unambigously interpreted as an indication for quark-gluon plasma formation, nevertheless they clearly show that some collective effects are present in high energy nucleus-nucleus collisions. 84 refs. (author)

  6. The retrotrapezoid nucleus and breathing.

    Science.gov (United States)

    Guyenet, Patrice G; Stornetta, Ruth L; Abbott, Stephen B G; Depuy, Seth D; Kanbar, Roy

    2012-01-01

    The retrotrapezoid nucleus (RTN) is located in the rostral medulla oblongata close to the ventral surface and consists of a bilateral cluster of glutamatergic neurons that are non-aminergic and express homeodomain transcription factor Phox2b throughout life. These neurons respond vigorously to increases in local pCO(2) via cell-autonomous and paracrine (glial) mechanisms and receive additional chemosensory information from the carotid bodies. RTN neurons exclusively innervate the regions of the brainstem that contain the respiratory pattern generator (RPG). Lesion or inhibition of RTN neurons largely attenuates the respiratory chemoreflex of adult rats whereas their activation increases respiratory rate, inspiratory amplitude and active expiration. Phox2b mutations that cause congenital central hypoventilation syndrome in humans prevent the development of RTN neurons in mice. Selective deletion of the RTN Phox2b-VGLUT2 neurons by genetic means in mice eliminates the respiratory chemoreflex in neonates.In short, RTN Phox2b-VGLUT2 neurons are a major nodal point of the CNS network that regulates pCO(2) via breathing and these cells are probable central chemoreceptors. PMID:23080151

  7. Neutrino nucleus cross sections

    CERN Document Server

    Athar, M Sajjad; Singh, S K; Vacas, M J Vicente

    2008-01-01

    We present the results of our calculation which has been performed to study the nuclear effects in the quasielastic, inelastic and deep inelastic scattering of neutrinos(antineutrinos) from nuclear targets. These calculations are done in the local density approximation. We take into account the effect of Pauli blocking, Fermi motion, Coulomb effect, renormalization of weak transition strengths in the nuclear medium in the case of the quasielastic reaction. The inelastic reaction leading to production of pions is calculated in a $\\Delta $- dominance model taking into account the renormalization of $\\Delta$ properties in the nuclear medium and the final state interaction effects of the outgoing pions with the residual nucleus. We discuss the nuclear effects in the $F_{3}^{A}(x)$ structure function in the deep inelastic neutrino(antineutrino) reaction using a relativistic framework to describe the nucleon spectral function in the nucleus.

  8. Antinucleon-nucleus interactions

    Energy Technology Data Exchange (ETDEWEB)

    Dover, C.B.

    1987-01-01

    Recent experimental and theoretical results on anti p-nucleus interactions are reviewed. We focus on determinations of the anti p optical potential from elastic scattering, the use of (anti p, anti p') inelastic scattering to reveal aspects of the spin-isospin dependence of N anti N amplitudes, and some puzzling features of (anti p, anti n) charge exchange reactions on nuclei. 47 refs., 7 figs.

  9. Polarized Proton Nucleus Scattering

    OpenAIRE

    Kopeliovich, B. Z.; Trueman, T. L.

    2000-01-01

    We show that, to a very good approximation, the ratio of the spin-flip to the non-flip parts of the elastic proton-nucleus amplitude is the same as for proton-nucleon scattering at very high energy. The result is used to do a realistic calculation of the analyzing power A_N for pC scattering in the Coulomb-nuclear interference (CNI) region of momentum transfer.

  10. Hadron nucleus interactions

    International Nuclear Information System (INIS)

    The elastic and inelastic scattering of intermediate energy (less than or equal to 1 GeV) protons by nuclei is considered first. The discussion focuses on the determination of the proton-nucleus optical potential in terms of the elementary nucleon-nucleon scattering amplitudes and the properties of the target and residual nucleus. The result is a series of terms for the optical potential. Then the interaction of pions with nuclei for energies in the neighborhood of the Δ-resonance is discussed. In this energy domain an incident pion will with high probability be absorbed by a nucleon to produce the Δ-resonance and thus form a Δ-particle hole state in the nucleus. Next, the subject of hypernuclei is taken up. The Λ hypernuclei and a recently observed Σ hypernuclei comprise situations in which the core nucleus can be probed by a baryon of roughly the same mass as a nucleon, with similar albeit not identical interactions with nucleons. But the Λ (or Σ) does not need to satisfy the Pauli exclusion principle with respect to the nucleons, and therefore can be in orbits forbidden to it if it were a nucleon. As the energy of the projectile increases, it becomes correspondingly more important to take relativistic effects into account. The importance of these effects is strikingly revealed by experiments involving the collision of ultrarelativistic hadrons, protons, pions, kaons (up to Fermilab energies) with nuclei. This phenomenon forms part of the final topic, which includes as well as the collision of relativistic heavy ion projectiles with nuclei. A nuclear Weiszaecker-Williams method developed for dealing with peripheral collisions is described. 32 figures, 10 tables

  11. Limits to the formation of hot fusion nuclei in nucleus-nucleus collisions

    International Nuclear Information System (INIS)

    The maximum temperature which can be sustained by a nucleus is discussed. Methods used to measure the temperature; values measured in fusion reactors; theoretical investigations on the value of the limiting temperature; and information about dynamical limitations on excitation energy storage in nuclei are reviewed. It is concluded that thermalized fusion nuclei are formed at temperatures up to 5 MeV for heavy systems and 6 MeV for medium mass systems. Thermal energy in central nucleus-nucleus collisions might not exceed some saturation value due to two effects: a sharing of the deposited energy into compressional and thermal energies; and a dynamical competition between thermal energy deposition and fast pre-equilibrium emission

  12. Oscillations of moments in high-energy nucleus-nucleus collisions

    Institute of Scientific and Technical Information of China (English)

    杨红艳; 周代翠; 钱琬燕; 王晓荣

    2001-01-01

    The definitions of density function and moment of multiplicity distribution are introduced,and the method of moment analysis in e+ e- and proton-proton (pp) interactions is extended into nu-cleus-nucleus (AA) interactions. We analyze the data for relativistic nucleus-nucleus collisions and cal-culate the values of Hq for charged particle multiplicity distributions, by which we study systematically the dependences of Hq on incident energy, mass of colliding system, pseudorapidity interval, centrality and truncation of multiplicity. We compare the oscillation structures induced by e + e-, pp and AA inter-actions, and the comparison and analysis are carried out between experimental data and QCD predic-tion. The latest results are given in this paper.

  13. Bridging the Gap, Facing the Challenge—the 26th Great Wall International Congress of Cardiology (GW-ICC)

    OpenAIRE

    Zhang, Yingmei; Ren, Jun

    2016-01-01

    The joint venue of the 26th Great Wall International Congress of Cardiology (GW-ICC) & Asia Pacific Heart Congress 2015 (APHC 2015) & International Congress Cardiovascular Prevention and Rehabilitation 2015 (ICCPR 2015) were held from October 29 to November 01, 2015 at the China National Convention Center (CNCC), Beijing, China. This year’s conference focused on cardiovascular disease prevention, health promotion, education and training, as well as disease management and rehabilitation.

  14. Nuorten yhteiskunnalliset tiedot, osallistuminen ja asenteet : kansainvälisen ICCS 2009 -tutkimuksen päätulokset

    OpenAIRE

    Suoninen, Annikka; Kupari, Pekka; Törmäkangas, Kari

    2010-01-01

    Kansainvälisen ICCS-tutkimuksen tavoitteena on selvittää, millaiset valmiudet nuorilla on toimia ja osallistua aktiivisina kansalaisina 21. vuosisadan yhteiskunnassa. Tutkimukseen osallistui 38 maata eri puolilta maailmaa. Julkaisu kertoo tutkimuksen ensimmäisistä tuloksista. Millaiset ovat peruskoulun 8.-luokkalaisten yhteiskunnalliset tiedot ja miten ne ovat muuttuneet 10 vuoden aikana? Kiinnostavatko politiikka ja yhteiskunnalliset asiat nuoria? Millaista on nuorten osallistuminen koul...

  15. Bridging the Gap, Facing the Challenge-the 26(th) Great Wall International Congress of Cardiology (GW-ICC).

    Science.gov (United States)

    Zhang, Yingmei; Ren, Jun

    2016-02-01

    The joint venue of the 26(th) Great Wall International Congress of Cardiology (GW-ICC) & Asia Pacific Heart Congress 2015 (APHC 2015) & International Congress Cardiovascular Prevention and Rehabilitation 2015 (ICCPR 2015) were held from October 29 to November 01, 2015 at the China National Convention Center (CNCC), Beijing, China. This year's conference focused on cardiovascular disease prevention, health promotion, education and training, as well as disease management and rehabilitation. PMID:26885499

  16. 神经肽Y在杏仁中央核内对禁食大鼠摄食的调节方式%Regulation of neuropeptide Y in central nucleus of amygdaloid on feeding of fasted rats

    Institute of Scientific and Technical Information of China (English)

    朱永香; 王倩; 王爽; 于玮; 南瑛; 曹健

    2013-01-01

    Objective To examine the regulatory mode of neuropeptide Y (NPY) in the central nucleus of amygdala (CeA) on feeding of fasted rats,and to explore the possible mechanism.Methods 34 male SD rats were chosen,and 10 rats of them were divided into feeding group(n=5) and fasted 24 h group(n=5),and the rat brain was obtained.The expressions of NPY and neuropeptide Y 1 receptor (Y1R)in CeA were detected by immunohistochemical staining method.The other 24 rats were implanted cannula in CeA.The postoperative 12 rats were randomly divided into 2 groups,and the rats in one group were injected with NPY and the rats in another group were injected with saline in CeA(control 1 group),after 1,2 and 4 h,the intake of food was detected.The other postoperative 12 rats were randomly divided into 2 groups,and the rats in one group were injected with Y1R antagonist and the rats in another group were injected with saline in CeA(control 2 group),after 1,2 and 4 h,the intake of food was detected.Results Compared with feeding group,the NPY expression in CeA of the rats in fasted 24 h group was significantly increased (P<0.05),and the Y1R expression in CeA of the rats in fasted 24 h group was significantly decreased (P<0.05).Compared with control 1 group,the intake of food of the rats injected with NPY in CeA within 1 h was significantly increased(P<0.05) ; compared with control 2 group,the intake of food of the rats injected with Y1R antagonist in CeA within 1 h was significantly decreased(P<0.05).Conclusion NPY in CeA has promotion effect on the feeding of fasted rats,and the mechanism may be regulated by Y1 receptor.%目的:观察神经肽Y(NPY)在杏仁中央核(CeA)内对禁食大鼠摄食的调节方式,并探讨其可能的作用机制.方法:选择雄性SD大鼠34只,将其中10只大鼠随机分为正常摄食组与禁食24 h组,每组5只,取大鼠脑组织,应用免疫组织化学方法检测大鼠CeA内NPY及其Y1受体的表达;剩余24只大鼠

  17. Leukocyte nucleus segmentation and nucleus lobe counting

    Directory of Open Access Journals (Sweden)

    Zheng Zong-Han

    2010-11-01

    Full Text Available Abstract Background Leukocytes play an important role in the human immune system. The family of leukocytes is comprised of lymphocytes, monocytes, eosinophils, basophils, and neutrophils. Any infection or acute stress may increase or decrease the number of leukocytes. An increased percentage of neutrophils may be caused by an acute infection, while an increased percentage of lymphocytes can be caused by a chronic bacterial infection. It is important to realize an abnormal variation in the leukocytes. The five types of leukocytes can be distinguished by their cytoplasmic granules, staining properties of the granules, size of cell, the proportion of the nuclear to the cytoplasmic material, and the type of nucleolar lobes. The number of lobes increased when leukemia, chronic nephritis, liver disease, cancer, sepsis, and vitamin B12 or folate deficiency occurred. Clinical neutrophil hypersegmentation has been widely used as an indicator of B12 or folate deficiency.Biomedical technologists can currently recognize abnormal leukocytes using human eyes. However, the quality and efficiency of diagnosis may be compromised due to the limitations of the biomedical technologists' eyesight, strength, and medical knowledge. Therefore, the development of an automatic leukocyte recognition system is feasible and necessary. It is essential to extract the leukocyte region from a blood smear image in order to develop an automatic leukocyte recognition system. The number of lobes increased when leukemia, chronic nephritis, liver disease, cancer, sepsis, and vitamin B12 or folate deficiency occurred. Clinical neutrophil hypersegmentation has been widely used as an indicator of B12 or folate deficiency. Results The purpose of this paper is to contribute an automatic leukocyte nuclei image segmentation method for such recognition technology. The other goal of this paper is to develop the method of counting the number of lobes in a cell nucleus. The experimental results

  18. Nucleus-Nucleus Collision as Superposition of Nucleon-Nucleus Collisions

    International Nuclear Information System (INIS)

    Angular distributions of charged particles produced in 16O and 32S collisions with nuclear track emulsion were studied at momenta 4.5 and 200 A GeV/c. Comparison with the angular distributions of charged particles produced in proton-nucleus collisions at the same momentum allows to draw the conclusion, that the angular distributions in nucleus-nucleus collisions can be seen as superposition of the angular distributions in nucleon-nucleus collisions taken at the same impact parameter bNA, that is mean impact parameter between the participating projectile nucleons and the center of the target nucleus

  19. Nucleus-Nucleus Collision as Superposition of Nucleon-Nucleus Collisions

    Energy Technology Data Exchange (ETDEWEB)

    Orlova, G.I.; Adamovich, M.I.; Aggarwal, M.M.; Alexandrov, Y.A.; Andreeva, N.P.; Badyal, S.K.; Basova, E.S.; Bhalla, K.B.; Bhasin, A.; Bhatia, V.S.; Bradnova, V.; Bubnov, V.I.; Cai, X.; Chasnikov, I.Y.; Chen, G.M.; Chernova, L.P.; Chernyavsky, M.M.; Dhamija, S.; Chenawi, K.El; Felea, D.; Feng, S.Q.; Gaitinov, A.S.; Ganssauge, E.R.; Garpman, S.; Gerassimov, S.G.; Gheata, A.; Gheata, M.; Grote, J.; Gulamov, K.G.; Gupta, S.K.; Gupta, V.K.; Henjes, U.; Jakobsson, B.; Kanygina, E.K.; Karabova, M.; Kharlamov, S.P.; Kovalenko, A.D.; Krasnov, S.A.; Kumar, V.; Larionova, V.G.; Li, Y.X.; Liu, L.S.; Lokanathan, S.; Lord, J.J.; Lukicheva, N.S.; Lu, Y.; Luo, S.B.; Mangotra, L.K.; Manhas, I.; Mittra, I.S.; Musaeva, A.K.; Nasyrov, S.Z.; Navotny, V.S.; Nystrand, J.; Otterlund, I.; Peresadko, N.G.; Qian, W.Y.; Qin, Y.M.; Raniwala, R.; Rao, N.K.; Roeper, M.; Rusakova, V.V.; Saidkhanov, N.; Salmanova, N.A.; Seitimbetov, A.M.; Sethi, R.; Singh, B.; Skelding, D.; Soderstrem, K.; Stenlund, E.; Svechnikova, L.N.; Svensson, T.; Tawfik, A.M.; Tothova, M.; Tretyakova, M.I.; Trofimova, T.P.; Tuleeva, U.I.; Vashisht, Vani; Vokal, S.; Vrlakova, J.; Wang, H.Q.; Wang, X.R.; Weng, Z.Q.; Wilkes, R.J.; Yang, C.B.; Yin, Z.B.; Yu, L.Z.; Zhang, D.H.; Zheng, P.Y.; Zhokhova, S.I.; Zhou, D.C

    1999-03-01

    Angular distributions of charged particles produced in {sup 16}O and {sup 32}S collisions with nuclear track emulsion were studied at momenta 4.5 and 200 A GeV/c. Comparison with the angular distributions of charged particles produced in proton-nucleus collisions at the same momentum allows to draw the conclusion, that the angular distributions in nucleus-nucleus collisions can be seen as superposition of the angular distributions in nucleon-nucleus collisions taken at the same impact parameter b{sub NA}, that is mean impact parameter between the participating projectile nucleons and the center of the target nucleus.

  20. Thermal Bremsstrahlung probing nuclear multifragmentation in nucleus-nucleus collisions around the Fermi energy

    International Nuclear Information System (INIS)

    The thermodynamical properties of nuclear matter at moderate temperatures and densities, in the vicinity of the predicted nuclear liquid-gas phase transition, are studied using as experimental probe the hard-photons (Eγ > 30 MeV) emitted in nucleus-nucleus collisions. Photon and charged-particle production in four different heavy-ion reactions (Ar36 + Au197, Ag107, Ni58, C12 at 60 A*MeV) is measured exclusively and inclusively coupling the TAPS photon spectrometer with two charged-particle and intermediate-mass-fragment detectors covering nearly 4π. We confirm that Bremsstrahlung emission in first-chance (off-equilibrium) proton-neutron collisions (pnγ) is the dominant origin of hard photons. We also firmly establish the existence of a thermal radiation component emitted in second-chance proton-neutron collisions. This thermal Bremsstrahlung emission takes place in semi-central and central nucleus-nucleus reactions involving heavy targets. We exploit this observation i) to demonstrate that thermal equilibrium is reached during the reaction, ii) to establish a new thermometer of nuclear matter based on Bremsstrahlung photons, iii) to derive the thermodynamical properties of the excited nuclear sources and, in particular, to establish a 'caloric curve' (temperature versus excitation energy), and iv) to assess the time-scales of the nuclear break-up process. (author)

  1. Antineutron-nucleus annihilation

    CERN Document Server

    Botta, E

    2001-01-01

    The n-nucleus annihilation process has been studied by the OBELIX experiment at the CERN Low Energy Antiproton Ring (LEAR) in the (50-400) MeV/c projectile momentum range on C, Al, Cu, Ag, Sn, and Pb nuclear targets. A systematic survey of the annihilation cross- section, sigma /sub alpha /(A, p/sub n/), has been performed, obtaining information on its dependence on the target mass number and on the incoming n momentum. For the first time the mass number dependence of the (inclusive) final state composition of the process has been analyzed. Production of the rho vector meson has also been examined. (13 refs).

  2. Neutrino-nucleus interactions

    Energy Technology Data Exchange (ETDEWEB)

    Gallagher, H.; /Tufts U.; Garvey, G.; /Los Alamos; Zeller, G.P.; /Fermilab

    2011-01-01

    The study of neutrino oscillations has necessitated a new generation of neutrino experiments that are exploring neutrino-nuclear scattering processes. We focus in particular on charged-current quasi-elastic scattering, a particularly important channel that has been extensively investigated both in the bubble-chamber era and by current experiments. Recent results have led to theoretical reexamination of this process. We review the standard picture of quasi-elastic scattering as developed in electron scattering, review and discuss experimental results, and discuss additional nuclear effects such as exchange currents and short-range correlations that may play a significant role in neutrino-nucleus scattering.

  3. Higgs-Boson Production in Nucleus-Nucleus Collisions

    Science.gov (United States)

    Norbury, John W.

    1992-01-01

    Cross section calculations are presented for the production of intermediate-mass Higgs bosons produced in ultrarelativistic nucleus-nucleus collisions via two photon fusion. The calculations are performed in position space using Baur's method for folding together the Weizsacker-Williams virtual-photon spectra of the two colliding nuclei. It is found that two photon fusion in nucleus-nucleus collisions is a plausible way of finding intermediate-mass Higgs bosons at the Superconducting Super Collider or the CERN Large Hadron Collider.

  4. Unveiling the nucleus of NGC 7172

    Science.gov (United States)

    Smajić, S.; Fischer, S.; Zuther, J.; Eckart, A.

    2012-08-01

    Aims: We present the results of near-infrared (NIR) H + K European Southern Observatory SINFONI integral field spectroscopy (IFS) of the Seyfert 2 galaxy NGC 7172. We investigate the central 800 pc, concentrating on excitation conditions, morphology, and stellar content. NGC 7172 was selected from a sample of the ten nearest Seyfert 2 galaxies from the Veron-Cetty & Veron catalogue. All objects were chosen as test cases for adaptive optics (AO) assisted observations that allow a detailed study (at high spatial and spectral resolution) of the nuclear and host environments. NGC 7172 has a prominent dustlane crossing the central galaxy region from east to west, which makes it an ideal candidate to investigate the effect of obscuration by strong galactic extinction on (active) galaxies and their classification. Methods: The NIR is less influenced by dust extinction than optical light and is sensitive to the mass-dominating stellar populations. SINFONI integral field spectroscopy combines NIR imaging and spectroscopy and provides us with the opportunity to analyze several emission and absorption lines to investigate the stellar populations and ionization mechanisms over the 4″ × 4″ field of view (FOV). Results: We present emission and absorption line measurements in the central 800 pc of NGC 7172. The detection of [Si vi] and broad Paα and Brγ components are clear signs of an accreting super-massive black hole hiding behind the prominent dustlane at visible wavelengths. Hot temperatures of about 1300 K are indicative of a dusty torus in the nuclear region. Narrow components of Paα and Brγ enable us to make an extinction measurement. Our measures of the molecular hydrogen lines, hydrogen recombination lines, and [Fe ii] indicate that the excitation of these lines is caused by an active galactic nucleus. The central region of the galactic disk is predominantly inhabited by gas, dust, and an old K-M type giant stellar population. The gaseous, molecular, and

  5. Sampling a Cometary Nucleus

    Science.gov (United States)

    Keller, Horst Uwe; Küppers, Michael; Kuehrt, Ekkehard

    Understanding of the physics and chemistry of the proto solar nebula and the formation of our planetary system is a prime objective of planetary research. The key role of comets as witnesses of the early conditions is well established. Material, dust and condensed compounds, were stored at very low temperatures in cometary nuclei and have since been preserved. These icy grains are the source material out of which all planetary bodies formed in more or less complex processes. Analysis of this material will provide fundamental (in its original meaning) information about the proto solar nebula and the physical processes that dominated during the final stages of its collapse toward the ecliptic plane and the formation of the sun. Recent observations of comets and modelling results have shown that pristine material can be found at a few centimetres or decimetres below the surface of cometary nuclei. Comets have been visited by space probes over the last 20 years with increasing frequency. All observations and analyses show that cometary nuclei have low density, are porous, and their (surface) material has a very low tensile strength. Therefore collecting a sample from a cometary nucleus is relatively simple (simpler than from any other planetary body) and does not even require landing (touch and go). The Rosetta spacecraft is on its way to rendezvous a short period comet. The evolution of cometary activity will be followed from its onset through perihelion. The spacecraft will be operated in the near nucleus environment over several months providing extensive experience. It is now the time to conceive and prepare a comet nucleus sample return (CNSR) mission. The focus of such a mission must lie on the sampling and the return of the material. The concept of a CNSR mission will be discussed based on our understanding of cometary nuclei consolidated by the recent Stardust and Deep Impact results. Taking advantage of the easy sample collection brings a CNSR mission well

  6. DIAGEN-generator of inelastic nucleus-nucleus interaction diagrams

    International Nuclear Information System (INIS)

    Description of the program code generating inelastic nucleus-nucleus interaction diagrams is given. Probabilities of various diagram appearance are determined within the framework of Glauber approximation. The code allows one to determine cross sections of any processes and the number of spectator nucleons. 12 refs.; 2 figs

  7. Modelling and experimental investigation of transient heat transfer and hydrodynamics in LTSC and HTSC cables of ICCS type

    Science.gov (United States)

    Pavlov, Yu. M.; Yakovlev, I. V.; Terentiev, Yu. A.; Antipov, V. I.

    Results of experimental investigation of transient heat transfer and hydrodynamics of two phase flow in the channel with forced nitrogen circulation under pulse heating conditions are presented. Experimental relationships of channel wall temperature, heat transfer coefficient, pressure in the channel and time of boiling onset and that of crisis of heat transfer from mass flow rate, amplitude of heat pulse and relative channel length are obtained. Experimental results illustrate some regularities of transient heat transfer and hydraulic processes in models of HTSC cable of ICCS type.

  8. 25th IAEA Fusion Energy Conference: summary of sessions EX/S, EX/W and ICC

    Science.gov (United States)

    Sen, A.

    2015-10-01

    This paper provides a summary overview, based on papers presented at the 25th IAEA Fusion Energy Conference (FEC), in the area of magnetic confinement experiments related to stability (EX/S), wave-plasma interactions, current drive, heating, energetic particles (EX/W) and innovative confinement concepts (ICCs). A selection of results that represent progress made since the last FEC in a few important thematic areas that are relevant for the successful and safe operation of future fusion devices like ITER, is highlighted.

  9. 采用ICC-qPCR法分析渤海湾表层海水中的轮状病毒%ICC-qPCR Analysis on the infectious rotavirus in the surface seawater of Bohai Bay

    Institute of Scientific and Technical Information of China (English)

    明红霞; 董玉波; 任莹利; 王林同; 朱琳

    2012-01-01

    Rotavirus (RV) is the major cause of severe gastroenteritis, especially for infants and children. Due to its long duration and low dose-response in the water environment, it is urgent to establish a rapid and effective method to quantify this pathogen. Molecular biological assays have overcome time-consuming, as well as insensitive disadvantages of traditional cell culture method. However, viral inlectivity can not be analyzed by this method. Therefore, integration of the cell culture techniques and the reverse transcription quantitative PCR (ICC-RT-qPCR) was introduced in 2010 and 2011 to identify the contamination by rotaviruses in winter seawater samples of Bohai Bay, Tianjin, China. 500-mL seawater was concentrated, cultivated for 48h, and then quantified by qPCR. ICC-qPCR revealed that 3 of 7 samples were positive for infectious rotavirus. The concentration of rotavirus was from 1.8×102 copies to 3.8×103 copies, and estimated at 1 to 39 PFU/L The result confirmed that ICC-qPCR in combination with the real-time PCR method not only reduced the detection duration, improved sensitivity, but also able to quantitate the rotavirus. Hence, it will become a practical tool for widespread studies on aquatic environmental monitoring for viral contamination.%轮状病毒是引起婴幼儿急性腹泻的重要病原体之一,在水环境中存活时间长,导致人类感染的剂量低,因此寻求一种快速高效的定量检测海水中的轮状病毒方法势在必行.传统的细胞培养技术不但耗时,而且灵敏度低,现代分子生物学技术虽然克服了上述缺点,但是其感染性的信息无从获得.因此,本文建立了细胞培养结合实时定量PCR (ICC-qPCR)的方法,并于2010年冬季对渤海湾天津近岸重点海域表层海水中具有感染性的轮状病毒进行了定量调查.500 mL海水经浓缩,4.8h细胞培养之后,用qPCR方法在7个海水样品中检测出3个样品具有感染性,其测定值范围为1.8×102 copies-3.8

  10. Antiproton-nucleus interaction

    Science.gov (United States)

    Cugnon, J.; Vandermeulen, J.

    The antiproton-nucleus physics is reviewed. On the experimental side, the recent results obtained at the LEAR, BNL and KEK facilities are analyzed. A brief summary of the main pp and pn experimental data is also given. The antiproton-nucleus interaction can lead to elasic, inelastic and charge exchange scattering and to annihilation. The latter is very dominant. The scattering cross-sections are usually analyzed in terms of complex potential models. The relationship between potentials, charge conjugation and Dirac phenomenology is discussed. Much emphasis is put on the dynamics of the antiproton annihilation on nuclei. The energy transfer, pion absorption and target response are analyzed within the intranuclear cascade model. Special interest is devoted to strangeness production, hypernucleus formation and possible annihilation on two nucleons. Signatures for this new process are searched in experimental data. Finally, the highly debated question of quark-gluon formation is analyzed. Cet article constitue une revue de la physique antiproton-noyau. Du point de vue expérimental, cette revue porte particulièrement sur les récents résultats obtenus à LEAR, BNL et KEK. On y a aussi inclus une mise à jour des faits expérimentaux principaux pour pp et pn. L'interaction antiproton-noyau conduit à la diffusion élastique, inélastique et d'xA9change de charge et à des processus d'annihilation. Habituellement, les expériences de diffusion sont analysées en termes de potentiels complexes. La relation entre ces potentiels, la conjugaison de charge et la phénoménologie de Dirac est discutée. On s'est particulièrement intéressé à la dynamique de l'annihilation d'antiprotons sur des noyaux. Le transfert d'énergie, l'absorption de pions et la réponse de la cible sont analysés dans le cadre du modèle de cascade intranucléaire. Certains autres points sont discutés plus en détail: la production d'étrangeté, la formation d'hypernoyaux et l'annihilation sur

  11. Revisiting the supratrigeminal nucleus in the rat.

    Science.gov (United States)

    Fujio, T; Sato, F; Tachibana, Y; Kato, T; Tomita, A; Higashiyama, K; Ono, T; Maeda, Y; Yoshida, A

    2016-06-01

    The supratrigeminal nucleus (Vsup), originally proposed as a premotoneuron pool in the trigeminal reflex arc, is a key structure of jaw movement control. Surprisingly, however, the location of the rat Vsup has not precisely been defined. In light of our previous cat studies, we made two hypotheses regarding the rat Vsup: (1) the Vsup is cytoarchitectonically distinguishable from its surrounding structures; (2) the Vsup receives central axon terminals of the trigeminal mesencephalic nucleus (Vmes) neurons which are primary afferents innervating muscle spindles of jaw-closing muscles and periodontal ligaments around the teeth. To test the first hypothesis, we examined the cytoarchitecture of the rat Vsup. The Vsup was identified as an area medially adjacent to the dorsomedial part of trigeminal principal sensory nucleus (Vp), and extended from the level just rostral to the caudal two-thirds of the trigeminal motor nucleus (Vmo) to the level approximately 150μm caudal to the Vmo. Our rat Vsup was much smaller and its location was considerably different in comparison to the Vsup reported previously. To evaluate the second hypothesis, we tested the distribution patterns of Vmes primary afferent terminals in the cytoarchitectonically identified Vsup. After transganglionic tracer applications to the masseter, deep temporal, and medial pterygoid nerves, a large number of axon terminals were observed in all parts of Vsup (especially in its medial part). After applications to the inferior alveolar, infraorbital, and lingual nerves, a small number of axon terminals were labeled in the caudolateral Vsup. The Vsup could also be identified electrophysiologically. After electrical stimulation of the masseter nerve, evoked potentials with slow negative component were isolated only in the Vsup. The present findings suggest that the rat Vsup can be cytoarchitectonically and electrophysiologically identified, receives somatotopic termination of the trigeminal primary afferents, and

  12. Dynamic image correlation spectroscopy (ICS) and two-color image cross-correlation spectroscopy (ICCS): concepts and application

    Science.gov (United States)

    Wiseman, Paul W.; Squier, Jeffrey A.; Wilson, Kent R.

    2000-05-01

    The interaction of macromolecules in space and time are known to be important for the regulation of many biochemical reactions. Image correlation spectroscopy (ICS) was recently introduced as an imaging analog of fluorescence correlation spectroscopy optimized for measuring the aggregation state of fluorescently labeled macromolecules on the surface of biological cells. We present two novel developments of dynamic ICS that will greatly enhance our abilities to measure molecular interactions as a function of time and space in living cells. We illustrate the use of a rapid scan two-photon microscope system to collect image series at high time resolution (30 frames/s) for dynamic ICS analysis. Secondly, we demonstrate the implementation of two-color image cross-correlation spectroscopy (ICCS) with a CLSM using multiple wavelength excitation, and with two-photon excitation of samples containing two different fluorescent species. Cross-correlation analysis allows the degree of co- localization of two different fluorophores to be measured directly. By performing two-color ICCS, we can monitor the interactions of non-identical labeled macromolecules as a function of time and space. We describe the experimental setup for both methods and illustrate the application for measurements of the diffusion coefficients of singly and doubly labeled fluorescent microspheres in aqueous solutions.

  13. A Fast linking approach for CMYK to CMYK conversion preserving black separation in ICC color management system

    Science.gov (United States)

    Zeng, Huanzhao

    2003-12-01

    In the linking step of the standard ICC color management workflow for CMYK to CMYK conversion, a CMM takes an AToBn tag (n = 0, 1, or 2) from a source ICC profile to convert a color from the source color space to PCS (profile connection space), and then takes a BToAn tag from the destination ICC profile to convert the color from PCS to the destination color space. This approach may give satisfactory result perceptually or colorimetrically. However, it does not preserve the K channel for CMYK to CMYK conversion, which is often required in graphic art"s market. The problem is that the structure of a BtoAn tag is designed to convert colors from PCS to a device color space ignoring the K values from the source color space. Different approaches have been developed to control K in CMYK to CMYK printing, yet none of them well fits into the "Profile - PCS - Profile" model in the ICC color management system. A traditional approach is to transform the source CMYK to the destination CMYK by 1-D TRC curves and GCR/UCR tables. This method is so simple that it cannot accurately transform colors perceptually or colorimetrically. Another method is to build a 4-D CMYK to CMYK closed-loop lookup table (LUT) (or a deviceLink ICC profile) for the color transformation. However, this approach does not fit into opened color management workflows for it ties the source and the destination color spaces in the color characterization step. A specialized CMM may preserve K for a limit number of colors by mapping those CMYK colors to some carefully chosen PCS colors in both the AToBi tag and the BToAi tag. A more complete solution is to move to smart linking in which gamut mapping is performed in the real-time linking at a CMM. This method seems to solve all problems existed in the CMYK to CMYK conversion. However, it introduces new problems: 1) gamut mapping at real-time linking is often unacceptable slow; 2) gamut mapping may not be optimized or may be unreliable; 3) manual adjustment for

  14. Retrotrapezoid nucleus, respiratory chemosensitivity and breathing automaticity

    Science.gov (United States)

    Guyenet, Patrice G.; Bayliss, Douglas A.; Stornetta, Ruth L.; Fortuna, Michal G.; Abbott, Stephen B.; Depuy, Seth D.

    2009-01-01

    SUMMARY Breathing automaticity and CO2 regulation are inseparable neural processes. The retrotrapezoid nucleus (RTN), a group of glutamatergic neurons that express the transcription factor Phox2b, may be a crucial nodal point through which breathing automaticity is regulated to maintain CO2 constant. This review updates the analysis presented in prior publications. Additional evidence that RTN neurons have central respiratory chemoreceptor properties is presented but this is only one of many factors that determine their activity. The RTN is also regulated by powerful inputs from the carotid bodies and, at least in the adult, by many other synaptic inputs. We also analyze how RTN neurons may control the activity of the downstream central respiratory pattern generator. Specifically, we review the evidence which suggests that RTN neurons a) innervate the entire ventral respiratory column, and b) control both inspiration and expiration. Finally, we argue that the RTN neurons are the adult form of the parafacial respiratory group in neonate rats. PMID:19712903

  15. Formation of light particles in nucleus-nucleus collisions

    International Nuclear Information System (INIS)

    The principal experimental results on the yield of the light charged particles in nucleus-nucleus collisions at the low and intermediate energies are reviewed. Inclusive spectra of light particles and their coincidences with the characteristic KX-rays, γ-rays, neutrons, projectile-like fragments, other light particles, fission fragments, and evaporation residues are analyzed. The main theoretical models used for the description of the light particle formation are briefly outlined together with their merits and shortcomings. The unsolved problems of fast light particle formation, in particular, and of nucleus-nucleus interaction dynamics, on the whole, are discussed with the outlooks of new experiments able to clear up some of these problems. (author) 144 refs., 40 figs., 2 tabs

  16. Antiproton Production in 11.5 A GeV/c Au+Pb Nucleus-Nucleus Collisions

    OpenAIRE

    E687 Collaboration; al, T. A. Armstrong et

    1997-01-01

    We present the first results from the E864 collaboration on the production of antiprotons in 10% central 11.5 A GeV/c Au+Pb nucleus collisions at the Brookhaven AGS. We report invariant multiplicities for antiproton production in the kinematic region 1.4

  17. A Monte Carlo Generator for High Energy Nucleus- Nucleus Collision

    OpenAIRE

    Hassan, N. M.; El-Harby, N.; Hussein, M. T.

    1999-01-01

    A Monte Carlo simulator is presented to reproduce data of nucleus-nucleus interactions at high energies. The program is designed in a microscopic point of view, where the cascade approach is applied. Moreover, each nucleon from both the target and the projectile is followed up on the time scale along the collision time. The effect of the mean field that depends on the nuclear density is considered. Elastic and inelastic scattering are allowed for the nucleon binary collisions during the casca...

  18. Study of Strange and Multistrange Particles in Ultrarelativistic Nucleus-Nucleus Collisions

    CERN Multimedia

    Vande vyvre, P; Feofilov, G; Snoeys, W; Hetland, K F; Campbell, M; Klempt, W

    2002-01-01

    % NA57\\\\ \\\\ The goal of the experiment is to study the production of strange and multi-strange particles in nucleus-nucleus collisions. This study was initiated at the OMEGA spectrometer, where three ion experiments have been performed: WA85 (S-W and p-W collisions at 200 A GeV/c), WA94 (S-S and p-S collisions at 200 A GeV/c) and WA97 (Pb-Pb, p-Pb and p-Be collisions at 160 A GeV/c).\\\\ \\\\ The experiment aims at extending the scope of WA97 by:\\\\ \\\\ - investigating the beam energy dependence of the enhancements of multi-strange particle production reported by the previous experiments, and by\\\\ \\\\\\\\ \\\\- measuring the yields of strange and multi-strange particles over an extended centrality range compared with the previous experiments.\\\\ \\\\ The apparatus consists mainly of silicon pixel detector planes.

  19. Particle densities in ultrarelativistic heavy ion reactions extrapolated from proton-nucleus collisions

    International Nuclear Information System (INIS)

    Rapidity density distributions in central ultra-relativistic heavy ion reactions are estimated from high energy proton-nucleus collisions and compared with some cosmic ray events. Deviations from a simple scaling of pA reactions are observed. (author)

  20. Nucleus management with irrigating vectis

    OpenAIRE

    Srinivasan Aravind

    2009-01-01

    The main objective in modern cataract surgery is to achieve a better unaided visual acuity with rapid post-surgical recovery and minimal surgery-related complications. Early visual rehabilitation and better unaided vision can be achieved only by reducing the incision size. In manual small incision cataract surgery (MSICS), incision is between 5.5 to 7 mm. Once the nucleus is prolapsed into the anterior chamber, it can be extracted through the tunnel. Nucleus extraction with an irrigating vect...

  1. Energy Provisions of the ICC-700, LEED for Homes, and ENERGY STAR Mapped to the 2009 IECC

    Energy Technology Data Exchange (ETDEWEB)

    Britt, Michelle L.; Sullivan, Robin S.; Kora, Angela R.; Makela, Eric J.; Makela, Erin

    2011-05-06

    This document provides the results of a comparison of building energy efficient elements of the ICC-700 National Green Building Standard, LEED for Homes, and ENERGY STAR versions 2, 2.5, and 3.0 to the 2009 International Energy Conservation Code (2009 IECC). This comparison will provide a tool for states and local municipalities as they consider adoption of these programs. The comparison is presented in a series of appendices. The first appendix provides a summary chart that visually represents the comprehensive comparison of the programs to the 2009 IECC topic areas. Next there are a series of individual tables (one appendix for each program) that include the specific program mapping to the 2009 IECC elements with comments that briefly discuss how well the elements mapped. Finally, a comprehensive table is included that shows all five of the programs mapped to the 2009 IECC elements to allow a detailed comparison.

  2. Hadron multiplicities and chemical freeze-out conditions in proton-proton and nucleus-nucleus collisions

    Science.gov (United States)

    Vovchenko, V.; Begun, V. V.; Gorenstein, M. I.

    2016-06-01

    New results of the NA61/SHINE Collaboration at the CERN SPS on mean hadron multiplicities in proton-proton (p+p) interactions are analyzed within the transport models and the hadron resonance gas (HRG) statistical model. The chemical freeze-out parameters in p+p interactions and central Pb+Pb (or Au+Au) collisions are found and compared with each other in the range of the center-of-mass energy of the nucleon pair √{sN N}=3.2 -17.3 GeV. The canonical ensemble formulation of the HRG model is used to describe mean hadron multiplicities in p+p interactions and the grand canonical ensemble in central Pb+Pb and Au+Au collisions. The chemical freeze-out temperatures in p+p interactions are found to be larger than the corresponding temperatures in central nucleus-nucleus collisions.

  3. Static polarization effects on the nucleus-nucleus potential

    International Nuclear Information System (INIS)

    The authors the nucleus-nucleus potential as a function of two variables : the distance between the centres of the nuclei R or equivalently the distance s0 between the surfaces s0 = R - R1 - R2 where Ri (i = 1,2) are the nuclear radii, and a surface thickness parameter a. The second variable was introduced in order to investigate the possibility of the polarization of the nuclei seen as a change in the thickness of the surface layer. (orig./AH)

  4. Selected Experimental Highlights from Nucleus-Nucleus Collisions at RHIC

    CERN Document Server

    Huang, H Z

    2006-01-01

    Nucleus-nucleus collisions at RHIC produce high temperature and high energy density matter which exhibits partonic degrees of freedom. We will discuss measurements of nuclear modification factors for light hadrons and non-photonic electrons from heavy quark decays, which reflect the flavor dependence of energy loss of high momentum partons traversing the dense QCD medium. The hadronization of bulk partonic matter exhibits collectivity in effective partonic degrees of freedom. Nuclear collisions at RHIC provide an intriguing environment, where many constituent quark ingredients are readily available for possible formation of exotic particles through quark coalescences or recombinations.

  5. Dynamical nucleus-nucleus potential at short distances

    OpenAIRE

    Jiang, Yongying; Wang, Ning; Li, Zhuxia; Scheid, Werner

    2010-01-01

    The dynamical nucleus-nucleus potentials for fusion reactions 40Ca+40Ca, 48Ca+208Pb and 126Sn+130Te are studied with the improved quantum molecular dynamics (ImQMD) model together with the extended Thomas-Fermi approximation for the kinetic energies of nuclei. The obtained fusion barrier for 40Ca+40Ca is in good agreement with the extracted fusion barrier from the measured fusion excitation function, and the depth of the fusion pockets are close to the results of time-dependent Hartree-Fock c...

  6. Central collisions of heavy ions

    International Nuclear Information System (INIS)

    This report describes the activities of the Heavy Ion Physics Group at the University of California, Riverside from October 1, 1991 to September 30, 1992. During this period, the program focused on particle production at AGS energies, and correlation studies at the Bevalac in nucleus-nucleus central collisions. As part of the PHENIX collaboration, contributions were made to the Preliminary Conceptual Design Report (pCDR), and work on a RHIC silicon microstrip detector R ampersand D project was performed

  7. Nucleus management with irrigating vectis

    Directory of Open Access Journals (Sweden)

    Srinivasan Aravind

    2009-01-01

    Full Text Available The main objective in modern cataract surgery is to achieve a better unaided visual acuity with rapid post-surgical recovery and minimal surgery-related complications. Early visual rehabilitation and better unaided vision can be achieved only by reducing the incision size. In manual small incision cataract surgery (MSICS, incision is between 5.5 to 7 mm. Once the nucleus is prolapsed into the anterior chamber, it can be extracted through the tunnel. Nucleus extraction with an irrigating vectis is a very simple technique, which combines mechanical and hydrostatic forces to express out the nucleus. This technique is time-tested with good results and more than 95% of nuclei in MSICS are extracted in this way offering all the merits of phacoemulsification with the added benefits of having wider applicability, better safety, shorter learning curve and lower cost.

  8. Nucleus pulposus atherectomy decompression and ozone nucleolysis combine lumbar traction in the treatment of central type lumbar disc herniation%髓核旋切臭氧牵引联合治疗腰椎间盘突出症

    Institute of Scientific and Technical Information of China (English)

    苏启超; 王建光; 耿海涛; 李海芳; 朱春阳; 贾艳玲

    2013-01-01

    Objective To investigate the clinic technique and effect of treating lumbar disc herniation (LDH) with decompressor and ozone injection combined lumbar traction after surgery.Methods 110 contained LDH patients were randomly divided into two group:decompressor and ozone group,decompressor and ozone combined lumbar traction after surgery group.Under the guidance of CT,fifty-five patients in group A were treated by disc decompression with Decompressor through poster olateral approach,then ozone was injected into the lumbar disc or out side the lumbar disc,and the other fifty-five patients in group B were treated by lumbar traction after surgery that disc decompression and ozone injection same as the group A in once a day and one week of treatment.The theraputic effect was evaluated by comparing VAS,effective rate of therapy before and after treatment.Results The VAS score of two groups at 1,3,7 days between pre-and post-treatment had singificantly different(t =2.159,2.163,2.169,2.167,2.173,2.192,all P <0.05).110 case were followed up after 6 and 12 months,The good-excellent rate of therapy in B group 12 months were better than those of A group (χ2 =74.23,75.11,all P<0.05).Conclusion Decompressor combined ozone injection and lumbar traction after surgery is an effective menthod for treatment of the central type mbar disc herniation.%目的 观察经皮穿刺髓核旋切减压与腰椎间盘臭氧注射联合术后牵引的综合治疗方案用于中央型腰椎间盘突出症的疗效.方法 110例腰椎间盘突出症患者随机分为两组,A组55例Decompressor髓核旋切器,采用经典的后外侧穿刺入路,行经皮髓核旋切腰椎间盘减压术,然后向腰椎间盘内、外注射臭氧;B组55例,在A组的治疗方案基础上,手术后当天开始行连续7d腰椎牵引.予以治疗前和治疗后VAS评分、评价两组疗效并随访观察.结果 两组治疗后1d、3d、7 d VAS评分与治疗前差异有统计学意义(t=2.159、2.163、2.169、2

  9. Anti p-nucleus interaction

    International Nuclear Information System (INIS)

    Status and future prospects of antiproton-nucleus scattering experiments are presented. These scattering experiments were conducted at antiproton beam momentums of 300 and 600 MeV/c on target nuclei of 6Li, 12C, 16O, 18O, 40Ca, 48Ca, and 208Pb. Antiproton-proton reactions investigated antiproton-nucleus bound or resonant states in antiproton reactions with d, 6Li, 12C, 63Cu, and 209Bi. Inelastic scattering experiments investigated the spin-isospin dependence of the NN interactions. 19 refs., 1 fig., 1 tab

  10. Fluctuations and correlations in nucleus-nucleus collisions within transport approaches

    Energy Technology Data Exchange (ETDEWEB)

    Konchakovski, Volodymyr P.

    2009-10-01

    The current thesis is devoted to a systematic study of fluctuations and correlations in heavy-ion collisions, which might be considered as probes for the phase transition and the critical point in the phase diagram, within the Hadron-String- Dynamics (HSD) microscopic transport approach. This is a powerful tool to study nucleus-nucleus collisions and allows to completely simulate experimental collisions on an event-by-event basis. Thus, the transport model has been used to study fluctuations and correlations including the influence of experimental acceptance as well as centrality, system size and collision energy. The comparison to experimental data can separate the effects induced by a phase transition since there is no phase transition in the HSD version used here. Firstly the centrality dependence of multiplicity fluctuations has been studied. Different centrality selections have been performed in the analysis in correspondence to the experimental situation. For the fixed target experiment NA49 events with fixed numbers of the projectile participants have been studied while in the collider experiment PHENIX centrality classes of events have been defined by the multiplicity in certain phase space region. A decrease of participant number fluctuations (and thus volume fluctuations) in more central collisions for both experiments has been obtained. Another area of this work addresses to transport model calculations of multiplicity fluctuations in nucleus-nucleus collisions as a function of colliding energy and system size. This study is in full correspondence to the experimental program of the NA61 Collaboration at the SPS. Central C+C, S+S, In+In, and Pb+Pb nuclear collisions at Elab = 10, 20, 30, 40, 80, 158 AGeV have been investigated. The expected enhanced fluctuations - attributed to the critical point and phase transition - can be observed experimentally on top of a monotonic and smooth 'hadronic background'. These findings should be helpful for the

  11. Fluctuations and correlations in nucleus-nucleus collisions within transport approaches

    International Nuclear Information System (INIS)

    The current thesis is devoted to a systematic study of fluctuations and correlations in heavy-ion collisions, which might be considered as probes for the phase transition and the critical point in the phase diagram, within the Hadron-String- Dynamics (HSD) microscopic transport approach. This is a powerful tool to study nucleus-nucleus collisions and allows to completely simulate experimental collisions on an event-by-event basis. Thus, the transport model has been used to study fluctuations and correlations including the influence of experimental acceptance as well as centrality, system size and collision energy. The comparison to experimental data can separate the effects induced by a phase transition since there is no phase transition in the HSD version used here. Firstly the centrality dependence of multiplicity fluctuations has been studied. Different centrality selections have been performed in the analysis in correspondence to the experimental situation. For the fixed target experiment NA49 events with fixed numbers of the projectile participants have been studied while in the collider experiment PHENIX centrality classes of events have been defined by the multiplicity in certain phase space region. A decrease of participant number fluctuations (and thus volume fluctuations) in more central collisions for both experiments has been obtained. Another area of this work addresses to transport model calculations of multiplicity fluctuations in nucleus-nucleus collisions as a function of colliding energy and system size. This study is in full correspondence to the experimental program of the NA61 Collaboration at the SPS. Central C+C, S+S, In+In, and Pb+Pb nuclear collisions at Elab = 10, 20, 30, 40, 80, 158 AGeV have been investigated. The expected enhanced fluctuations - attributed to the critical point and phase transition - can be observed experimentally on top of a monotonic and smooth 'hadronic background'. These findings should be helpful for the optimal

  12. A Direct Neurokinin B Projection from the Arcuate Nucleus Regulates Magnocellular Vasopressin Cells of the Supraoptic Nucleus.

    Science.gov (United States)

    Pineda, R; Sabatier, N; Ludwig, M; Millar, R P; Leng, G

    2016-04-01

    Central administration of neurokinin B (NKB) agonists stimulates immediate early gene expression in the hypothalamus and increases the secretion of vasopressin from the posterior pituitary through a mechanism that depends on the activation of neurokinin receptor 3 receptors (NK3R). The present study reports that, in the rat, immunoreactivity for NK3R is expressed in magnocellular vasopressin and oxytocin neurones in the supraoptic nucleus (SON) and paraventricular nucleus (PVN) of the hypothalamus, and that NKB immunoreactivity is expressed in fibres in close juxtaposition with vasopressin neurones at both of these sites. Retrograde tracing in the rat shows that some NKB-expressing neurones in the arcuate nucleus project to the SON and, in mice, using an anterograde tracing approach, it is found that kisspeptin-expressing neurones of the arcuate nucleus, which are known to co-express NKB, project to the SON and PVN. Finally, i.c.v. injection of the NK3R agonist senktide is shown to potently increase the electrical activity of vasopressin neurones in the SON in vivo with no significant effect detected on oxytocin neurones. The results suggest that NKB-containing neurones in the arcuate nucleus regulate the secretion of vasopressin from magnocellular neurones in rodents, and the possible significance of this is discussed. PMID:26610724

  13. EOS: A time projection chamber for the study of nucleus-nucleus collisions at the Bevalac

    International Nuclear Information System (INIS)

    The conceptual design is presented for a detector to identify and measure (Δp/p ≅ 1%) most of the 200 or so mid-rapidity charged particles (p, d, t, 3He, 4He, π+-, K+-) produced in each central nucleus-nucleus collision (Au + Au) at Bevalac energies, as well as K30 and Λ0. The beam particles and heavy spectator fragments are excluded from the detection volume by means of a central vacuum pipe. Particle identification is achieved by a combination of dE/dx measurements in the TPC, and of time-of-flight measurements in a scintillator array. The TPC is single-ended and its end cap is entirely covered with cathode pads (about 25,000 pads and about 1000 anode wires). A non-uniform pad distribution is proposed to accommodate the high multiplicity of particles emitted at forward angles. The performance of the detector is assessed with regard to multihit capability, tracking, momentum resolution, particle identification, Λ0 reconstruction, space charge effects, field non-uniformity, dynamic range, data acquisition rate, and data analysis rate. 72 refs., 48 figs., 11 tabs

  14. EOS: A time projection chamber for the study of nucleus-nucleus collisions at the Bevalac

    Energy Technology Data Exchange (ETDEWEB)

    Pugh, H.G.; Odyniec, G.; Rai, G.; Seidl, P.

    1986-12-01

    The conceptual design is presented for a detector to identify and measure (..delta..p/p approx. = 1%) most of the 200 or so mid-rapidity charged particles (p, d, t, /sup 3/He, /sup 4/He, ..pi../sup + -/, K/sup + -/) produced in each central nucleus-nucleus collision (Au + Au) at Bevalac energies, as well as K/sub 3//sup 0/ and ..lambda../sup 0/. The beam particles and heavy spectator fragments are excluded from the detection volume by means of a central vacuum pipe. Particle identification is achieved by a combination of dE/dx measurements in the TPC, and of time-of-flight measurements in a scintillator array. The TPC is single-ended and its end cap is entirely covered with cathode pads (about 25,000 pads and about 1000 anode wires). A non-uniform pad distribution is proposed to accommodate the high multiplicity of particles emitted at forward angles. The performance of the detector is assessed with regard to multihit capability, tracking, momentum resolution, particle identification, ..lambda../sup 0/ reconstruction, space charge effects, field non-uniformity, dynamic range, data acquisition rate, and data analysis rate. 72 refs., 48 figs., 11 tabs.

  15. Heavy-ion nucleus scattering

    CERN Document Server

    Rahman, M A; Haque, S

    2003-01-01

    Heavy ion-nucleus scattering is an excellent laboratory to probe high spin phenomena, exotic nuclei and for the analysis of various exit channels. The Strong Absorption Model or the generalized diffraction models, which are semi-classical in nature, have been employed in the description of various heavy ion-nucleus scattering phenomena with reasonable success. But one needs to treat the deflection function (scattering angles) quantum mechanically in the Wave Mechanical picture for the appropriate description of the heavy-ion nucleus scattering phenomena. We have brought the mathematics for the cross-section of the heavy-ion nucleus scattering to an analytic expression taking account of the deflection function (scattering angles) quantum mechanically. sup 9 Be, sup 1 sup 6 O, sup 2 sup 0 Ne and sup 3 sup 2 S heavy-ion beams elastic scattering from sup 2 sup 8 Si, sup 2 sup 4 Mg and sup 4 sup 0 Ca target nuclei at various projectile energies over the range 20-151 MeV have been analysed in terms of the 2-paramet...

  16. Heavy-ion nucleus scattering

    International Nuclear Information System (INIS)

    Heavy ion-nucleus scattering is an excellent laboratory to probe high spin phenomena, exotic nuclei and for the analysis of various exit channels. The Strong Absorption Model or the generalized diffraction models, which are semi-classical in nature, have been employed in the description of various heavy ion-nucleus scattering phenomena with reasonable success. But one needs to treat the deflection function (scattering angles) quantum mechanically in the Wave Mechanical picture for the appropriate description of the heavy-ion nucleus scattering phenomena. We have brought the mathematics for the cross-section of the heavy-ion nucleus scattering to an analytic expression taking account of the deflection function (scattering angles) quantum mechanically. 9Be,16O, 20Ne and 32S heavy-ion beams elastic scattering from 28Si, 24Mg and 40Ca target nuclei at various projectile energies over the range 20-151 MeV have been analysed in terms of the 2-parameter formalism of the present quantal formulation and from the Strong Absorption Model for comparison. Typical fits are shown and the nuclear parameters obtained from the analyses of both approaches are presented. (author)

  17. Immunohistochemical distribution of Calbindin D-28K immunoreactivity in the central nervous system of adult cat

    Institute of Scientific and Technical Information of China (English)

    LIU Tao; LI Jin-lian; XIONG Kang-hui; LI Ji-shuo

    2002-01-01

    Objective: In order to get more information about the possible functions of Calbindin D-28K in the central nervous system of adult cat, the distribution of Calbindin D-28K in the central nervous system of adult cat was examined. Methods: Immunohistochemical staining techniques were used, and immunostained sections were observed under a light microscopy. Results: A high density of both immunoreactive perikarya and fibers were observed in the basal ganglia, amygdaloid complex, nucleus of the fields of Forel, subthalamic nucleus, paracentral nucleus, pulvinar nucleus, subthalamus, dorsal hypothalamic area, lateral hypothalamic area, anterior hypothalamus, suprachiasmatic nucleus, superior colliculus, inferior colliculus, oculomo-tor nucleus, superior olivary complex, marginal nucleus of the brachium conjunctivum, vestibular nuclei, the spinal trigeminal nucleus, nucleus of the solitary tract, cuneate nucleus, inferior olivary complex, dorsal motor nucleus of the vagus nerve, the molecular layer of the cerebellum, the purkinje cell layer of the cerebellum and in the laminae Ⅱ of the spinal cord, whereas the dentate gyrus, the central medial nucleus of the thalamus, the paracentral and central lateral nucleus of the thalamus, the lateral dorsal nucleus of the thalamus,the ventrolateral complex of the thalamus, the medioventral nucleus of the thalamus, the posterior hypothalamic area, the dorsal hypothalamic area, the infundibular nucleus, the dorsomedial hypothalamic nucleus and the interfascicular nucleus had just a high density of immunoreactive perikarya, and no positive fibres were detected in these areas. Conclusion: The present results showed that Calbindin D-28K-like immunoreactivity was widely distributed throughout the central nervous system of adult cat and might play an important role in the activities of the neurons in the central nervous system of adult cat.

  18. Divergent Projections of Catecholaminergic Neurons in the Nucleus of the Solitary Tract to Limbic Forebrain and Medullary Autonomic Brain Regions

    OpenAIRE

    Reyes, Beverly A. S.; Van Bockstaele, Elisabeth J.

    2006-01-01

    The nucleus of the solitary tract (NTS) is a critical structure involved in coordinating autonomic and visceral activities. Previous independent studies have demonstrated efferent projections from the NTS to the nucleus paragigantocellularis (PGi) and the central nucleus of the amygdala (CNA) in rat brain. To further characterize the neural circuitry originating from the NTS with postsynaptic targets in the amygdala and medullary autonomic targets, distinct green or red fluorescent latex micr...

  19. Formation of proton-fragments in hadron-nucleus and nucleus-nucleus collisions at high energies

    International Nuclear Information System (INIS)

    Full text: The investigation of production of protons in hadron- and nucleus-nucleus interactions is a key problem allowing one to establish the singularities of dynamics of nuclear interactions. The formation of proton-fragments at high energies of colliding particles proceeds within both the interaction of hadrons with nuclei and in the process of decay of the nucleus or its de-excitation at peripheral interactions. At different stages of interaction of impinging particle with target nucleus, the different mechanisms of formation of proton-fragments: the direct knock-out of intranuclear nucleons in the process of high energy cascade of an initial hadron, intranuclear cascade of produced particles, decay of the excited multi-nucleon fragments and of the thermalized remnant nucleus, and the coalescence of nuclear fragments to the new clusters are realized with the certain probability, connected to the interaction parameters (the interaction energy, the parameter of collision, the intranuclear density, the configuration of Fermi momentum of nucleons and clusters of target nucleus et al.). In its turn, the mechanisms of formation of the final nuclear fragments are closely related to the type of excitation of an initial nucleus. The peripheral interactions proceed at small transfers of the momentum of an impinging particle and represent the wide class of reactions covering the processes from diffractive or coulomb collective excitations of the whole nucleus to the direct quasi-elastic knock-out of the separate nucleons. Non-peripheral interactions are caused by comparatively high local transfers of momentum to the intranuclear clusters allowing the development of intranuclear cascade and the asymmetric redistribution of energy of an impinging particle. The central collisions causing the full decay of nucleus on nucleons or few-nucleon fragments, are the limiting case of the maximal development of the intranuclear cascade. The interaction of the initial particles with

  20. Cardiovascular responses to hydrogen peroxide into the nucleus tractus solitarius

    OpenAIRE

    Cardoso, Leonardo Máximo; Colombari, Débora Simões Almeida; Menani, José V; Toney, Glenn M.; Chianca, Deoclécio Alves; Colombari, Eduardo

    2009-01-01

    The nucleus tractus solitarius (NTS), a major hindbrain area involved in cardiovascular regulation, receives primary afferent fibers from peripheral baroreceptors and chemoreceptors. Hydrogen peroxide (H2O2) is a relatively stable and diffusible reactive oxygen species (ROS), which acting centrally, may affect neural mechanisms. In the present study, we investigated effects of H2O2 alone or combined with the glutamatergic antagonist kynurenate into the NTS on mean arterial pressure (MAP) and ...

  1. Eikonal approximation to deuteron-nucleus scattering at intermediate energies

    International Nuclear Information System (INIS)

    The full integral representation of the eikonal approximation to the scattering amplitude of spin-1 elastic scattering in the presence of central, spin-orbit and tensor interactions is derived. Eikonal calculations of the cross section and polarization observables in deuteron-nucleus scattering at intermediate energies using a relativistic model are found to reproduce successfully the partial wave calculations. copyright 1997 The American Physical Society

  2. Lap-joint resistance of Nb3Sn cable termination for the ICCS-HFTF 12-Tesla-Coil program

    International Nuclear Information System (INIS)

    Lap joint resistance as a function of current and magnetic field has been measured across prototypal 12 Tesla Coil conductor cable terminations. The terminations were at the ends of a 2.2 m Nb3Sn hairpin of internally cooled and cabled superconductor (ICCS), and were soft soldered to NbTi bus bars. The resulting lap joints were each 15 cm long with a contact area of 19.8 cm2. The maximum lap joint voltage drop was 75 μV at 21 kA and 4.2 K, with the cable center at zero magnetic field. This represents an upper bound on all measured voltage drops, including those with the cable center at 10 and 12 T, and corresponds to a maximum heat flux of 0.01 w/cm2. The results imply that the 12 Tesla Coil, with four lap joints, would dissipate less than 7 watts in the steady-state at 21 kA. The zero field results and results at cross fields of 10 and 12 T are discussed. Manufacturing and experimental parameters relevant to this study are also considered

  3. LAP joint resistance of Nb3 Sn cable terminations for the ICCS-HFTF 12 Tesla Coil program

    International Nuclear Information System (INIS)

    Lap joint resistance as a function of current and magnetic field has been measured across 12 Tesla Coil conductor cable terminations. The terminations were at the ends of a 2.2 m Nb3Sn hairpin of internally cooled and cabled superconductor (ICCS), and were soft soldered to NbTi bus bars. The resulting lap joints were each 15 cm long with a contact area of 19.8 cm2. The maximum measured lap joint voltage drop was 75 μV at 21 kA and 4.2 K, with the cable center at zero magnetic field. This represents an upper bound on all measured voltage drops, including those with the cable center at 10 and 12 T, and corresponds to a maximum heat flux of 0.01 w/ cm2 to pool boiling helium. The results imply that the 12 Tesla Coil, with four lap joints, would dissipate less than 7 watts in the steady-state at 21 kA. The zero field results and results at cross fields of 10 and 12 T are discussed. Manufacturing and experimental parameters relevant to this study are also considered

  4. Time evolution of the central region in ultrarelativistic heavy-ion collisions

    International Nuclear Information System (INIS)

    We investigate time development of the central region in ultrarelativistic nucleus-nucleus collisions by using the event generator URASiMA in order to study the space-time structure in high energy heavy-ion collisions. We focus on time dependence of particle-number densities and temperature of the central region in highly relativistic head-on nucleus-nucleus collisions. (author)

  5. Azimuthal correlation and collective behavior in nucleus-nucleus collisions

    Energy Technology Data Exchange (ETDEWEB)

    Mali, P.; Mukhopadhyay, A., E-mail: amitabha-62@rediffmail.com; Sarkar, S. [University of North Bengal, Department of Physics (India); Singh, G. [SUNY at Fredonia, Department of Computer and Information Science (United States)

    2015-03-15

    Various flow effects of nuclear and hadronic origin are investigated in nucleus-nucleus collisions. Nuclear emulsion data collected from {sup 84}Kr + Ag/Br interaction at an incident energy of 1.52 GeV per nucleon and from {sup 28}Si + Ag/Br interaction at an incident energy of 14.5 GeV per nucleon are used in the investigation. The transverse momentum distribution and the flow angle analysis show that collective behavior, like a bounce-off effect of the projectile spectators and a sidesplash effect of the target spectators, are present in our event samples. From an azimuthal angle analysis of the data we also see a direct flow of the projectile fragments and of the produced charged particles. On the other hand, for both data samples the target fragments exhibit a reverse flow, while the projectile fragments exhibit an elliptic flow. Relevant flow parameters are measured.

  6. Azimuthal correlation and collective behavior in nucleus-nucleus collisions

    International Nuclear Information System (INIS)

    Various flow effects of nuclear and hadronic origin are investigated in nucleus-nucleus collisions. Nuclear emulsion data collected from 84Kr + Ag/Br interaction at an incident energy of 1.52 GeV per nucleon and from 28Si + Ag/Br interaction at an incident energy of 14.5 GeV per nucleon are used in the investigation. The transverse momentum distribution and the flow angle analysis show that collective behavior, like a bounce-off effect of the projectile spectators and a sidesplash effect of the target spectators, are present in our event samples. From an azimuthal angle analysis of the data we also see a direct flow of the projectile fragments and of the produced charged particles. On the other hand, for both data samples the target fragments exhibit a reverse flow, while the projectile fragments exhibit an elliptic flow. Relevant flow parameters are measured

  7. N body simulations of the nucleus of M 31

    CERN Document Server

    Emsellem, E; Emsellem, Eric; Combes, Francoise

    1997-01-01

    We test through stellar N-body simulations some scenarios to explain the dynamics of the peculiar nucleus of the Andromeda galaxy (M~31): although HST observations reveal a double nucleus morphology, the rotation field is almost symmetric around the bulge gravity centre and the velocity dispersion is off-centred. We show that any m=1 perturbation has a very short life-time (a few 10$^5$ yr). Assuming that the bright peak (P1) is a cold stellar cluster infalling into the nucleus, and that the large central velocity gradient is due to a central dark mass (in the range 7~$10^7$--$10^8$~\\Msun), we obtain a reasonably good fit to the observations. However, if this cluster lies in the central 20 pc, we estimate the life-time of the cluster to be less than 0.5~Myr. The dynamical friction is more efficient than estimated by analytic formulae, and is essentially due to the deformation of the stellar cluster through the huge tidal forces provided by the black hole. We show that the cluster cannot be on a circular orbit...

  8. Neuropeptide Y infusion into the shell region of the rat nucleus accumbens increases extracellular levels of dopamine

    DEFF Research Database (Denmark)

    Sørensen, Gunnar; Wegener, Gregers; Hasselstrøm, Jørgen;

    2009-01-01

    Increases in extracellular dopamine in the shell region of the nucleus accumbens are centrally involved in mediating reinforcement of addictive drugs. Neuropeptide Y (NPY) and its receptors are present in the nucleus accumbens and have been implicated in addiction mechanisms. This study further e...

  9. Kaonic nuclei and kaon-nucleus interactions

    CERN Document Server

    Ikuta, K; Masutani, K

    2002-01-01

    Although kaonic atoms provide valuable information concerning the K sup - -nucleus interaction at low energies, they cannot fully determine the K sup - - nucleus optical potential. We demonstrate that K sup - nuclear bound states, if they exist, can be useful in investigating the K sup - -nucleus interaction, especially in the interior of the nucleus. In order to show this possibility, we calculate the double differential cross sections for (K sup - , P) using the Green function method. (author)

  10. Computational Science - ICCS 2009

    Science.gov (United States)

    Allen, Gabrielle; Nabrzyski, Jarosław; Seidel, Edward; van Albada, Geert Dick; Dongarra, Jack; Sloot, Peter M. A.

    Representing knowledge with the use of ontology description languages offers several advantages arising from knowledge reusability, possibilities of carrying out reasoning processes and the use of existing concepts of knowledge integration. In this work we are going to present an environment for the integration of knowledge expressed in such a way. Guaranteeing knowledge integration is an important element during the development of the Semantic Web. Thanks to this, it is possible to obtain access to services which offer knowledge contained in various distributed databases associated with semantically described web portals. We will present the advantages of the multi-agent approach while solving this problem. Then, we will describe an example of its application in systems supporting company management knowledge in the process of constructing supply-chains.

  11. Glucagon-Like Peptide 1 Receptors in Nucleus Accumbens Affect Food Intake

    OpenAIRE

    Dossat, Amanda M.; Lilly, Nicole; Kay, Kristen; Williams, Diana L.

    2011-01-01

    Central glucagon-like peptide 1 receptor (GLP-1R) stimulation suppresses food intake, and hindbrain GLP-1 neurons project to numerous feeding-relevant brain regions. One such region is the nucleus accumbens (NAc), which plays a role in reward and motivated behavior. Using immunohistochemical and retrograde tracing techniques in rats, we identified a robust projection from GLP-1 neurons in the nucleus of the solitary tract to the NAc. We hypothesized that activation of NAc GLP-1Rs suppresses f...

  12. Shape Evolution of the Compound Nucleus in the Superheavy Element Synthesis Reaction via the BUU Model

    Institute of Scientific and Technical Information of China (English)

    WEI Liang; LIU Yu-Xin

    2005-01-01

    @@ By taking the BUU model, we simulate the superheavy element synthesis reaction. With the rotation effect being included in the B UU model, the effect of the non-centrality of the reaction 48 Ca + 238U→ 286112 is studied. It is shown that the promising impact parameter in the synthesis process can be released from zero to a value little smaller than the radius of the smaller nucleus involved in the reaction. Meanwhile, the compound nucleus may involve rich shape phases.

  13. Government's duty, as shipper and regulator, to keep spent fuel and waste on track: the ICC cases

    International Nuclear Information System (INIS)

    The transportation of radioactive materials, particularly spent nuclear fuel and radioactive waste, is at once the most studied and the most misunderstood category of hazardous materials transportation. During recent years, agencies of the United States Government have expended substantial effort and money not only studying many aspects of nuclear materials transportation but also litigating the safety and economics of such transportation. The movement of such materials has been attacked, not only by some state and local organizations, but also, by senior members of the transportation industry - the nation's railroads. This paper will discuss the government's role in the litigation which has developed between the railroad industry on one side and the government and the nuclear industry on the other. For more than two years, the Department of Energy has joined with representatives of other government agencies and the nuclear industry in an effort to preserve the viability of rail transportation of radioactive materials under reasonable common carrier tariffs. The southern and western railroads had restricted such transportation by requiring spent fuel and radioactive waste to move only in special trains. The eastern railroads and some midwestern roads had refused any common carriage for these commodities. Because tariff rates or the absence of such rates sparked this controversy, the United States Interstate Commerce Commission became the tribunal to hear these cases in the first instance.The issues heard included the adequacy of current safety requirements including packaging, testing and insurance. By the end of 1977, the ICC had issued initial decisions striking down the restrictive tariffs and ordering publication of tariffs where none existed. The litigation, however, will not be finally concluded for some time

  14. A New Perspective on the International Criminal Court: Why the Right Should Embrace the ICC and How America Can Use It

    Directory of Open Access Journals (Sweden)

    Ron Sievert

    2006-04-01

    Full Text Available In examining the response of the U.S. to the development of international law and institutions, one observes that the proponents of an international approach are traditionally idealists and those representing the left wing of American politics. The opposition tends to be led by conservatives and nationalists. A review of public statements surrounding the creation of the ICC reveals that it is no exception. The Court was formed, in the words of Kofi Annan, to help “ensure that no ruler, no State, no junta and no army anywhere can abuse human rights with impunity . . . that those who violate those rights will be punished.” Organizations such as Human Rights First, Human Rights Watch, Amnesty International and Citizens for Global Solutions have heavily promoted the ICC, and many international lawyers have expressed a “romantic attachment” to the idea that the Court can efficiently judge and deter war criminals and those who abuse human rights. However, as early as 1998, members of America’s political right wing, such as Senators Jessee Helms and John Ashcroft, have made it clear that they viewed the ICC as a threat to U.S. national sovereignty and our preeminence in world affairs. Senator Ashcroft stated that the Court was a “continuing threat to the national interest,” while Senator Helms declared that “the United States will never—and I repeat, never—allow its national security decisions to be judged by any international criminal court.” AmbassadorJohn Bolton and the Cato Institute also took strong and early stands against the Court, with Ambassador Bolton declaring that the adoption of the ICC breaches “the American citadel . . . , advocates of binding international law will be well on the way toward ultimate elimination of the ‘nation state.’”

  15. ICC-dementia (International Centenarian Consortium - dementia): an international consortium to determine the prevalence and incidence of dementia in centenarians across diverse ethnoracial and sociocultural groups

    OpenAIRE

    Brodaty, Henry; Woolf, Claudia; Andersen, Stacy; Barzilai, Nir; Brayne, Carol; Cheung, Karen Siu-Lan; Corrada, Maria M.; Crawford, John D; Daly, Catriona; Gondo, Yasuyuki; Hagberg, Bo; Hirose, Nobuyoshi; Holstege, Henne; Kawas, Claudia; Kaye, Jeffrey

    2016-01-01

    Background Considerable variability exists in international prevalence and incidence estimates of dementia. The accuracy of estimates of dementia in the oldest-old and the controversial question of whether dementia incidence and prevalence decline at very old age will be crucial for better understanding the dynamics between survival to extreme old age and the occurrence and risk for various types of dementia and comorbidities. International Centenarian Consortium – Dementia (ICC-Dementia) see...

  16. On the free electron state in the internal conversion and on the relation ICC approx. equal to vertical stroke psi(0) vertical stroke 2 for Tc-99m

    International Nuclear Information System (INIS)

    The final continuum electron states in the internal conversion (IC) process are considered under two points of view: 1) Regarding the potential for the free electron we use neither the unchanged atomic potential (no-hole model) nor the Rose- or the Band-hole model, but we apply another model which is introduced and discussed. The differences between the models are significant for low kinetic energies (a few keV). 2) Changes of the chemical or ionization state of the atom cause variations of the IC coefficients (ICC) not only via the bound states (proportionality relation ICC approx. equal to vertical stroke psi(0) vertical stroke 2), but in principle via the continuum states, too, especially for low kinetic energies or for inner shells. This effect is examined for the transition of Tc-99m (2.17 keV; E3) with variation of the transition energy. For the non-s-subshells it turns out that the simple proportionality relation holds for the Tc-99m transition, but for lower energy it has to be extended to the free electron wave functions. In the s-shells there appear discrepancies with decreasing energy even from the extended proportionality relation. A short description of the used ICC code is included in the paper. (orig.)

  17. Electromagnetic probes of a pure-glue initial state in nucleus-nucleus collisions at LHC

    CERN Document Server

    Vovchenko, V; Gorenstein, M I; Satarov, L M; Mishustin, I N; Kämpfer, B; Stoecker, H

    2016-01-01

    Partonic matter produced in the early stage of ultrarelativistic nucleus-nucleus collisions is assumed to be composed mainly of gluons, and quarks and antiquarks are produced at later times. To study the implications of such a scenario, the dynamical evolution of the chemically nonequilibrated system is described by the ideal (2+1)-dimensional hydrodynamics with a time dependent (anti)quark fugacity. The equation of state interpolates linearly between the lattice data for the pure gluonic matter and the lattice data for the chemically equilibrated quark-gluon plasma. The spectra and elliptic flows of thermal dileptons and photons are calculated for central Pb+Pb collisions at the LHC energy of $\\sqrt{s_{_{\\rm NN}}} = 2.76$ TeV. We test the sensitivity of the results to the choice of equilibration times, including also the case where the complete chemical equilibrium of partons is reached already at the initial stage. It is shown that a suppression of quarks at early times leads to a significant reduction of t...

  18. Charm quarks as a probe of matter produced in relativistic nucleus-nucleus collisions

    Directory of Open Access Journals (Sweden)

    Ali Yasir

    2014-04-01

    Full Text Available Direct measurement of hadrons containing charm quark carries important information about the initial stage of the nucleus-nucleus collision at relativistic energies. The study of open charm in Pb-Pb collisions at SPS energies will be a powerful tool to investigate the production of heavy flavours and their interaction with the medium produced in such collisions. A feasibility study was initiated for the measurement of the D0 mesons (open charm by its two-body decay into pion and kaon in central Pb-Pb collision at SPS energies in NA61/SHINE experiment. To generate the physical input we used AMPT (A Multi Phase Transport Model event generator and employed GEANT4 application to describe particle transport through the NA61/SHINE experimental setup supplemented by a future vertex detector (VD that will allow for precise vertex reconstruction close to the primary interaction point. The results of the simulation shows that this measurement is feasible with a dedicated VD which allows the precise tracking close to the target.

  19. Statistical Model of the Early Stage of nucleus-nucleus collisions with exact strangeness conservation

    CERN Document Server

    Poberezhnyuk, R V; Gorenstein, M I

    2015-01-01

    The Statistical Model of the Early Stage, SMES, describes a transition between confined and deconfined phases of strongly interacting matter created in nucleus-nucleus collisions. The model was formulated in the late 1990s for central Pb+Pb collisions at the CERN SPS energies. It predicted several signals of the transition (onset of deconfinement) which were later observed by the NA49 experiment. The grand canonical ensemble was used to calculate entropy and strangeness production. This approximation is valid for reactions with mean multiplicities of particles carrying conserved charges being significantly larger than one. Recent results of NA61/SHINE on hadron production in inelastic p+p interactions suggest that the deconfinement may also take place in these reactions. However, in this case mean multiplicity of particles with non-zero strange charge is smaller than one. Thus for the modeling of p+p interactions the exact strangeness conservation has to be implemented in the SMES. This extension of the SMES ...

  20. ARGININE VASOPRESSIN GENE EXPRESSION IN SUPRAOPTIC NUCLEUS AND PARAVENTRICULAR NUCLEUS OF HYPOTHALAMOUS FOLLOWING CEREBRAL ISCHEMIA AND REPERFUSION

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Background. Our previous studies indicated that the increased arginine vasopressin(AVP) in ischemic brain regions of gerbils could exacerbate the ischemic brain edema. This experiments is further clarify the relation between AVP and cerebral ischemia at the molecular level. Methods. The contents of AVP, AVP mRNA, AVP immunoreactive(ir) neurons in supraoptic nucleus(SON)and paraventricular nucleus(PVN) after cerebral ischemia and reperfusion were respectively determined by radioim-munoassay(RIA), immunocytochemistry( Ⅱ C), situ hybridization and computed image pattem analysis. Results. The contents of AVP in SON, PVN were increased, and the AVP ir positive neurons in SON and PVN were also significantly increased as compared with the controls after ischemia and reperfusion. And there were very light staining of AVP ir positive neurons in the other brain areas such as suprachiasmatic nucleus (SC) and periven-tricular hypothalamic nucleus (PE), but these have no significant changes as compared with the controls. During dif-ferent periods of cerebral ischemia (30~ 120 min) and reperfusion (30 min), AVP mRNA expression in SON and PVN were more markedly increased than the controls. Condusions. The transcription of AVP gene elevated, then promoting synthesis and release of AVP in SON,PVN. Under the specific condition of cerebral ischemia and repeffusion, the activity and contents of central AVP in-creased abnormally is one of the important factors which causes ischemia brain damage.

  1. Applying the elastic model for various nucleus-nucleus fusion

    International Nuclear Information System (INIS)

    The Elastic Model of two free parameters m,d given by Scalia has been used for wider energy regions to fit the available experimental data for potential barriers and cross sections. In order to generalize Scalia's formula in both sub- and above-barrier regions, we calculated m, d for pairs rather than those given by Scalia and compared the calculated cross sections with the experimental data. This makes a generalization of the Elastic Model in describing fusion process. On the other hand, Scalia's range of interacting systems was 24 ≤ A ≤194 where A is the compound nucleus mass number. Our extension of that model includes an example of the pairs of A larger than his final limit aiming to make it as a general formula for any type of reactants: light, intermediate or heavy systems. A significant point is the comparison of Elastic Model calculations with the well known methods studying complete fusion and compound nucleus formation, namely with the resultants of using Proximity potential with either Sharp or Smooth cut-off approximations

  2. Pion production at 1800 in nucleus-nucleus collisions

    International Nuclear Information System (INIS)

    A survey experiment of pion production at 1800 in nucleus-nucleus collisions is presented. Beams of 1.05 GeV/A and 2.1 GeV/A protons, alphas, and carbon were used, as well as proton beams of 0.80 GeV, 3.5 GeV, and 4.89 GeV, and argon beams of 1.05 GeV/A and 1.83 GeV/A. This is the first such experiment to use the heavier beams. Targets used ranged from carbon to lead. An in-depth review of the literature, both experimental and theoretical, is also presented. The systematics of the data are discussed, and comparisons are made both with prior experiments and with the predictions of the models reviewed. The cross sections appear consistent with a simple single nucleon-nucleon collision picture, without the need for collective or other exotic effects. Suggestions for future work are made

  3. Resonances in -light nucleus systems

    Indian Academy of Sciences (India)

    K P Khemchandani; N G Kelkar; M Nowakowski; B K Jain

    2006-04-01

    We locate resonances in -light nucleus elastic scattering using the time delay method. We solve few-body equations within the finite rank approximation in order to calculate the -matrices and hence the time delay for the - 3He and - 4He systems. We find a resonance very close to the threshold in - 3 He elastic scattering, at about 0.5 MeV above threshold with a width of ∼ 2 MeV. The calculations also hint at the presence of sub-threshold states in both the cases.

  4. Sub-Arcsecond 2D Photometry and Spectrography of the Nucleus of M31: The Supermassive Black Hole Revisited

    OpenAIRE

    Bacon, R.; Emsellem, E.; Monnet, G.; Nieto, J. L.

    1993-01-01

    Sub-arcsecond imagery (HRCAM, 0".35 - 0".57 FWHM) and two-dimensional spectrography (TIGER, 0".9 FWHM) of the central nucleus of M31 have been obtained at CFHT. The photometric data clearly show the double-peaked nucleus, in excellent agreement with a recent HST image by Lauer et al. 1993. We built deconvolved surface brightness models, using the multi-Gaussian expansion method. We then perform a detailed morphological analysis of the three central photometric components (bulge, nucleus and b...

  5. Structures and functions in the crowded nucleus: new biophysical insights

    Directory of Open Access Journals (Sweden)

    RonaldHancock

    2014-09-01

    Full Text Available Concepts and methods from the physical sciences have catalysed remarkable progress in understanding the cell nucleus in recent years. To share this excitement with physicists and encourage their interest in this field, this review offers an overview of how the physics which underlies structures and functions in the nucleus is becoming more clear thanks to methods which have been developed to simulate and study macromolecules, polymers, and colloids. The environment in the nucleus is very crowded with macromolecules, making entropic (depletion forces major determinants of interactions. Simulation and experiments are consistent with their key role in forming membraneless compartments such as nucleoli, PML and Cajal bodies, and discrete "territories" for chromosomes. The chromosomes, giant linear polyelectrolyte polymers, exist in vivo in a state like a polymer melt. Looped conformations are predicted in crowded conditions, and have been confirmed experimentally and are central to the regulation of gene expression. Polymer theory has revealed how the chromosomes are so highly compacted in the nucleus, forming a "crumpled globule" with fractal properties which avoids knots and entanglements in DNA while allowing facile accessibility for its replication and transcription. Entropic repulsion between looped polymers can explain the confinement of each chromosome to a discrete region of the nucleus. Crowding and looping are predicted to facilitate finding the specific targets of factors which modulate activities of DNA. Simulation shows that entropic effects contribute to finding and repairing potentially lethal double-strand breaks in DNA by increasing the mobility of the broken ends, favouring their juxtaposition for repair. Signaling pathways are strongly influenced by crowding, which favours a processive mode of response (consecutive reactions without releasing substrates. This new information contributes to understanding the sometimes counter

  6. New results on nuclear multifragmentation in nucleon-nucleus and nucleus-nucleus collisions at relativistic energies

    International Nuclear Information System (INIS)

    Some new aspects on the multifragmentation processes in nucleus-nucleus and nucleon-nucleus collisions at high energies are discussed in this work. Experimental data obtained in international collaborations (for example, MULTI Collaboration with KEK Tsukuba (Japan) and SKM 200 Collaboration with JINR Dubna (Russia)) are used to discuss new mechanisms in the target nucleus fragmentation. Correlations with stopping power, participant region size and energy density are included. Comparisons of the experimental results with the predictions of a phenomenological geometric model of intermediate mass fragment multiplicity, caloric curves and angular distributions are also presented. These results are used for global description of the multifragmentation processes in nucleon-nucleus and nucleus-nucleus collisions at relativistic energies. The size of the participant region and the average intermediate mass fragments multiplicity are taken into consideration using the free space probability. A few correlations between the deposited energy in the participant region and stability state of the intermediate mass fragments are presented in this work. The importance of the collision geometry in the multifragmentation processes is stressed. The results suggest different time moments for the incident nucleus fragmentation and for the target nucleus fragmentation. The associated entropies are distinct. (authors)

  7. Determination of Coil Inductances Cylindrical Iron Nucleus

    Directory of Open Access Journals (Sweden)

    Azeddine Mazouz

    2014-03-01

    Full Text Available The paper describes the investigation and development of a structure and performance characteristics of a coil iron nucleus cylindrical (C.I.N.C. The coil iron nucleus cylindrical is a nonlinear electro radio in which the moving of the nucleus in a sense or in other causes change in inductance and can reach extreme values at the superposition of nucleus and coil centers. The variation of the inductance and the degree of freedom of movement of the nucleus can lead to a device with electromechanical conversion The aim of this paper is the determination and visualization of self inductance and mutual of the (C.I.N.C based on geometric dimensions and the displacement of the nucleus.  

  8. Theoretical and experimental aspects of the multiple fragmentation reactions in the nucleus-nucleus collisions at intermediate energies

    International Nuclear Information System (INIS)

    The multiple fragmentation phenemenon is observed in the nucleus-nucleus collisions, at intermediate energies. The experimental and theoretical investigation of the reaction mechanism, is performed. The process is theoretically described, by applying dynamical and fragmentation models. The dynamical phase simulation is carried out by means of the Landau-Vlasov calculations, which are performed up to the obtention of a low density system. A statistical fragmentation model is applied. The results show that a multiple fragmentation must occur at intermediate energies; and that the reaction threshold energy and properties are bound to the nuclear matter state equation. The evolution mechanisms of the Argon-on-Aluminum system experiment, from 25 to 85 MeV per nucleon, are analyzed. It allows both the collisions classification as a function of their impact parameter and the selection of the central collisions. The existence of the multiple fragmentation phenomenom is pointed out

  9. An organism arises from every nucleus.

    OpenAIRE

    Nurullah Keklikoglu

    2009-01-01

    The fact that, cloning using somatic cell nuclear transfer (SCNT) method has been performed, opened new horizons for cloning, and changed the way of our understanding and approach to cell and nucleus. The progress in cloning technology, brought the anticipation of the ability to clone an organism from each somatic cell nucleus. Therefore, the 'Cell Theory' is about to take the additional statement as "An organism arises from every nucleus". The development of gene targeting procedures which c...

  10. Functional network inference of the suprachiasmatic nucleus.

    Science.gov (United States)

    Abel, John H; Meeker, Kirsten; Granados-Fuentes, Daniel; St John, Peter C; Wang, Thomas J; Bales, Benjamin B; Doyle, Francis J; Herzog, Erik D; Petzold, Linda R

    2016-04-19

    In the mammalian suprachiasmatic nucleus (SCN), noisy cellular oscillators communicate within a neuronal network to generate precise system-wide circadian rhythms. Although the intracellular genetic oscillator and intercellular biochemical coupling mechanisms have been examined previously, the network topology driving synchronization of the SCN has not been elucidated. This network has been particularly challenging to probe, due to its oscillatory components and slow coupling timescale. In this work, we investigated the SCN network at a single-cell resolution through a chemically induced desynchronization. We then inferred functional connections in the SCN by applying the maximal information coefficient statistic to bioluminescence reporter data from individual neurons while they resynchronized their circadian cycling. Our results demonstrate that the functional network of circadian cells associated with resynchronization has small-world characteristics, with a node degree distribution that is exponential. We show that hubs of this small-world network are preferentially located in the central SCN, with sparsely connected shells surrounding these cores. Finally, we used two computational models of circadian neurons to validate our predictions of network structure. PMID:27044085

  11. Functional network inference of the suprachiasmatic nucleus

    Energy Technology Data Exchange (ETDEWEB)

    Abel, John H.; Meeker, Kirsten; Granados-Fuentes, Daniel; St. John, Peter C.; Wang, Thomas J.; Bales, Benjamin B.; Doyle, Francis J.; Herzog, Erik D.; Petzold, Linda R.

    2016-04-04

    In the mammalian suprachiasmatic nucleus (SCN), noisy cellular oscillators communicate within a neuronal network to generate precise system-wide circadian rhythms. Although the intracellular genetic oscillator and intercellular biochemical coupling mechanisms have been examined previously, the network topology driving synchronization of the SCN has not been elucidated. This network has been particularly challenging to probe, due to its oscillatory components and slow coupling timescale. In this work, we investigated the SCN network at a single-cell resolution through a chemically induced desynchronization. We then inferred functional connections in the SCN by applying the maximal information coefficient statistic to bioluminescence reporter data from individual neurons while they resynchronized their circadian cycling. Our results demonstrate that the functional network of circadian cells associated with resynchronization has small-world characteristics, with a node degree distribution that is exponential. We show that hubs of this small-world network are preferentially located in the central SCN, with sparsely connected shells surrounding these cores. Finally, we used two computational models of circadian neurons to validate our predictions of network structure.

  12. Semiclassical description of hadron-nucleus collisions

    International Nuclear Information System (INIS)

    The yield of hadron-nucleus collisions are described in terms of the data on hadron-nucleon collisions and the data on the target-nucleus size and nucleon density distribution in it. A set of hadron-nucleus collision events may be treated as an interaction of hadron beam with a slab of nuclear matter. This way, the data on hadron-nucleus collisions are considered similarly as the data obtained in absorption experiments-when the interaction of a particle beam with a slab of a material is studied. The theory of probability and statistics is the natural mathematical apparatus for such kind

  13. Study of various models of nuclear interaction potentials: nucleon-nucleus and nucleus-nucleus systems

    International Nuclear Information System (INIS)

    Several models, performed within a mean field theory, are developed for the calculation of nucleon-nucleus interaction potentials. The first part of the thesis deals with the nucleon-nucleus average interaction. It is mainly devoted to the calculation of dynamical corrections to the Hartree-Fock approximation. Two approaches are used: a microscopic model performed in the framework of the nuclear structure approach and a semi-phenomenological one, based on the application of the dispersion relations to the empirical imaginary potential. Both models take into account finite size effects like collectivity or threshold effects which are important at low energy. The Green's function properties are used for both models. The second part of this work is devoted to the interaction potential between two heavy ions. This calculation, which is performed in the framework of the sudden approximation, uses the energy density formalism (Thomas-Fermi approximation). It has been extended to finite temperature. At T=0 the experimental fusion barriers of heavy systems are reproduced within 4%. Their temperature dependence is studied. The proximity scaling is checked and a universal function is obtained at T=0 and at finite temperature. It is found that the proximity theorem is well satisfied on the average. The dispersion around the mean behaviour increases with increasing temperature. At last, P+A* and α+A* interaction potentials are calculated within a double folding model using a schematic effective interaction

  14. Integrated Azimuthal Correlations in Nucleus-Nucleus Collisions at CERN SPS

    OpenAIRE

    Grebieszkow, Katarzyna; Mrowczynski, Stanislaw

    2011-01-01

    Azimuthal correlations of particles produced in nucleus-nucleus collisions at CERN SPS are discussed. The correlations quantified by the integral measure Phi are shown to be dominated by effects of collective flow.

  15. Physical meaning of the yields from hadron-nucleon, hadron-nucleus, and nucleus-nucleus collisions observed in experiments

    International Nuclear Information System (INIS)

    A physical meaning of the outcomes from hadronic and nuclear collision processes at high energies is presented, as prompted experimentally. The fast and slow stages in hadron-nucleus collisions are distinguished. Hadrons are produced via intermediate objects observed in hadron-nucleus collisions. The intermediate objects may be treated as the groups of quarks or the quark bags. 37 refs

  16. Antibaryon-nucleus bound states

    CERN Document Server

    Hrtánková, J

    2014-01-01

    We calculated antibaryon ($\\bar{B}$ = $\\bar{p}$, $\\bar{\\Lambda}$, $\\bar{\\Sigma}$, $\\bar{\\Xi}$) bound states in selected nuclei within the relativistic mean-field (RMF) model. The G-parity motivated $\\bar{B}$-meson coupling constants were scaled to yield corresponding potentials consistent with available experimental data. Large polarization of the nuclear core caused by $\\bar{B}$ was confirmed. The $\\bar{p}$ annihilation in the nuclear medium was incorporated by including a phenomenological imaginary part of the optical potential. The calculations using a complex $\\bar{p}$-nucleus potential were performed fully self-consistently. The $\\bar{p}$ widths significantly decrease when the phase space reduction is considered for $\\bar{p}$ annihilation products, but they still remain sizeable for potentials consistent with $\\bar{p}$-atom data.

  17. Color management in the real world: sRGB, ICM2, ICC, ColorSync, and other attempts to make color management transparent

    Science.gov (United States)

    Stokes, Michael

    1998-07-01

    A uniformly adopted color standards infrastructure has a dramatic impact on any color imaging industry and technology. This presentation begins by framing the current color standards situation in a historical context. A series of similar appearing infrastructure adoptions in color publishing during the last fifty years are reviewed and compared to the current events. This historical review is followed by brief technical, business and marketing reviews of two of the more popular recent color standards proposals, sRGB and ICC, along with their operating system implementations in the Microsoft and Apple operating systems. The paper concludes with a summary of Hewlett- Packard Company's and Microsoft's proposed future direction.

  18. Nucleus accumbens receives gastric vagal inputs

    Institute of Scientific and Technical Information of China (English)

    Sangeeta MEHENDALE; Jing-tian XIE; Han H AUNG; Xiong-Fei GUAN; Chun-Su YUAN

    2004-01-01

    AIM: To localize and characterize the response of single accumbal neurons to electrical stimulation of the gastric vagal fibers. METHODS: Unitary responses to electrical stimulation of the ventral and dorsal gastric vagal fibers which serve the proximal stomach were recorded extracellularly in the nucleus accumbens in anesthetized cats.RESULTS: The evoked units recorded in the nucleus accumbens consisted of phasic and tonic responses, with a mean latency of (396±43) ms. Convergence of ventral and dorsal gastric vagal inputs onto single phasic and tonic accumbal units was observed. For tonic inhibitory responses, convergence was exhibited when stimulation applied to both the ventral and dorsal gastric vagal branches resulted in a significantly longer inhibitory period than did stimulation of a single gastric vagal branch. Comparing the gastric vagally evoked accumbal unitary responses to the neuronal responses recorded in the nucleus tractus solitarius, parabrachial nucleus and hypothalamus in our previous studies, our data showed a higher percentage of single spike responses and shorter response duration's in the nucleus accumbens than in the other nuclei. This suggests that the synaptic drive from the gastric vagal inputs to the nucleus accumbens is less powerful than in the other structures. CONCLUSION: The present study localized and characterized gastric vagally evoked responses in the nucleus accumbens, which suggest that the nucleus accumbens may process gastric signals concerned with the ingestive process.

  19. Behavior of Charge Fluctuations in Relativistic Nucleus-nucleus Collisions

    Institute of Scientific and Technical Information of China (English)

    SA; Ben-hao; TAI; An

    2002-01-01

    Using a hadron and string cascade model JPCIAE, we have investigated the dependence ofevent-by-event charge fluctuations on (pseudo)rapidity window size, final state interaction, resonancedecay, centrality, and reaction energy for Pb + Pb collisions at SPS and LHC energies and for Au + Aucollisions at RHIC energies. The JPCIAE results of the charge fluctuations as a function of rapidity

  20. Integration of sensory quanta in cuneate nucleus neurons in vivo.

    Directory of Open Access Journals (Sweden)

    Fredrik Bengtsson

    Full Text Available Discriminative touch relies on afferent information carried to the central nervous system by action potentials (spikes in ensembles of primary afferents bundled in peripheral nerves. These sensory quanta are first processed by the cuneate nucleus before the afferent information is transmitted to brain networks serving specific perceptual and sensorimotor functions. Here we report data on the integration of primary afferent synaptic inputs obtained with in vivo whole cell patch clamp recordings from the neurons of this nucleus. We find that the synaptic integration in individual cuneate neurons is dominated by 4-8 primary afferent inputs with large synaptic weights. In a simulation we show that the arrangement with a low number of primary afferent inputs can maximize transfer over the cuneate nucleus of information encoded in the spatiotemporal patterns of spikes generated when a human fingertip contact objects. Hence, the observed distributions of synaptic weights support high fidelity transfer of signals from ensembles of tactile afferents. Various anatomical estimates suggest that a cuneate neuron may receive hundreds of primary afferents rather than 4-8. Therefore, we discuss the possibility that adaptation of synaptic weight distribution, possibly involving silent synapses, may function to maximize information transfer in somatosensory pathways.

  1. Neuronal Correlates of Fear Conditioning in the Bed Nucleus of the Stria Terminalis

    Science.gov (United States)

    Haufler, Darrell; Nagy, Frank Z.; Pare, Denis

    2013-01-01

    Lesion and inactivation studies indicate that the central amygdala (CeA) participates in the expression of cued and contextual fear, whereas the bed nucleus of the stria terminalis (BNST) is only involved in the latter. The basis for this functional dissociation is unclear because CeA and BNST form similar connections with the amygdala and…

  2. Music and the nucleus accumbens.

    Science.gov (United States)

    Mavridis, Ioannis N

    2015-03-01

    Music is a universal feature of human societies over time, mainly because it allows expression and regulation of strong emotions, thus influencing moods and evoking pleasure. The nucleus accumbens (NA), the most important pleasure center of the human brain (dominates the reward system), is the 'king of neurosciences' and dopamine (DA) can be rightfully considered as its 'crown' due to the fundamental role that this neurotransmitter plays in the brain's reward system. Purpose of this article was to review the existing literature regarding the relation between music and the NA. Studies have shown that reward value for music can be coded by activity levels in the NA, whose functional connectivity with auditory and frontal areas increases as a function of increasing musical reward. Listening to music strongly modulates activity in a network of mesolimbic structures involved in reward processing including the NA. The functional connectivity between brain regions mediating reward, autonomic and cognitive processing provides insight into understanding why listening to music is one of the most rewarding and pleasurable human experiences. Musical stimuli can significantly increase extracellular DA levels in the NA. NA DA and serotonin were found significantly higher in animals exposed to music. Finally, passive listening to unfamiliar although liked music showed activations in the NA. PMID:25102783

  3. Hydrogen sulfide augments synaptic neurotransmission in the nucleus of the solitary tract

    OpenAIRE

    Austgen, James R.; Hermann, Gerlinda E.; Dantzler, Heather A.; Richard C Rogers; Kline, David D.

    2011-01-01

    Within the brain stem, the nucleus tractus solitarii (NTS) serves as a principal central site for sensory afferent integration from the cardiovascular and respiratory reflexes. Neuronal activity and synaptic transmission in the NTS are highly pliable and subject to neuromodulation. In the central nervous system, hydrogen sulfide (H2S) is a gasotransmitter generated primarily by the enzyme cystathionine-β-synthase (CBS). We sought to determine the role of H2S, and its generation by CBS, in NTS...

  4. H2O2 INDUCES DELAYED HYPEREXCITABILITY IN NUCLEUS TRACTUS SOLITARII NEURONS

    OpenAIRE

    Ostrowski, Tim D.; Hasser, Eileen M.; Heesch, Cheryl M.; Kline, David D.

    2014-01-01

    Hydrogen peroxide (H2O2) is a stable reactive oxygen species and potent neuromodulator of cellular and synaptic activity. Centrally, endogenous H2O2 is elevated during bouts of hypoxia-reoxygenation, a variety of disease states, and aging. The nucleus tractus solitarii (nTS) is the central termination site of visceral afferents for homeostatic reflexes and contributes to reflex alterations during these conditions. We determined the extent to which H2O2 modulates synaptic and membrane properti...

  5. Analysis of Subthreshold Antiproton Production in p-Nucleus and Nucleus-Nucleus Collisions in the RBUU Approach

    CERN Document Server

    Teis, S; Maruyama, T; Mosel, U; Teis, Stefan; Cassing, Wolfgang; Maruyama, Tomoyuki; Mosel, Ulrich

    1994-01-01

    We calculate the subthreshold production of antiprotons in the Lorentz-covariant RBUU approach employing a weighted testparticle method to treat the antiproton propagation and absorption nonperturbatively. We find that the pbar differential cross sections are highly sensitive to the baryon and antiproton selfenergies in the dense baryonic environment. Adopting the baryon scalar and vector selfenergies from the empirical optical potential for proton-nucleus elastic scattering and from Dirac-Brueckner calculations at higher density rho > rho_0 we examine the differential pbar spectra as a function of the antiproton selfenergy. A detailed comparison with the available experimental data for p-nucleus and nucleus-nucleus reactions shows that the antiproton feels a moderately attractive mean-field at normal nuclear matter density rho_0 which is in line with a dispersive potential extracted from the free annihilation cross section.

  6. Nucleus accumbens stimulation in pathological obesity.

    Science.gov (United States)

    Harat, Marek; Rudaś, Marcin; Zieliński, Piotr; Birska, Julita; Sokal, Paweł

    2016-01-01

    One of the potential treatment methods of obesity is deep brain stimulation (DBS) of nucleus accumbens. We describe the case of 19 years old woman with hypothalamic obesity. She weighted 151.4 kg before DBS and the non-surgical methods proved to be inefficient. She was treated with implantation of DBS electrode to nucleus accumbens bilaterally. Results were measured with body mass index and neuropsychological tests. Follow-up was 14 months. Fourteen months after surgery weight was 138 kg, BMI was 48.3. Neuropsychological test results were intact. The presented case supports the thesis of treatment of obesity with nucleus accumbens stimulation. PMID:27154450

  7. Convergence of limb, visceral, and vertical semicircular canal or otolith inputs onto vestibular nucleus neurons

    Science.gov (United States)

    Jian, B. J.; Shintani, T.; Emanuel, B. A.; Yates, B. J.

    2002-01-01

    The major goal of this study was to determine the patterns of convergence of non-labyrinthine inputs from the limbs and viscera onto vestibular nucleus neurons receiving signals from vertical semicircular canals or otolith organs. A secondary aim was to ascertain whether the effects of non-labyrinthine inputs on the activity of vestibular nucleus neurons is affected by bilateral peripheral vestibular lesions. The majority (72%) of vestibular nucleus neurons in labyrinth-intact animals whose firing was modulated by vertical rotations responded to electrical stimulation of limb and/or visceral nerves. The activity of even more vestibular nucleus neurons (93%) was affected by limb or visceral nerve stimulation in chronically labyrinthectomized preparations. Some neurons received non-labyrinthine inputs from a variety of peripheral sources, including antagonist muscles acting at the same joint, whereas others received inputs from more limited sources. There was no apparent relationship between the spatial and dynamic properties of a neuron's responses to tilts in vertical planes and the non-labyrinthine inputs that it received. These data suggest that non-labyrinthine inputs elicited during movement will modulate the processing of information by the central vestibular system, and may contribute to the recovery of spontaneous activity of vestibular nucleus neurons following peripheral vestibular lesions. Furthermore, some vestibular nucleus neurons with non-labyrinthine inputs may be activated only during particular behaviors that elicit a specific combination of limb and visceral inputs.

  8. Study of Hadron Production in Hadron-Nucleus and Nucleus-Nucleus Collisions at the CERN SPS

    CERN Multimedia

    Selyuzhenkov, I; Rubbia, A; Di luise, S; Kowalski, S; Kaptur, E A; Kowalik, K L; Dominik, W M; Krasnoperov, A; Feofilov, G; Vinogradov, L; Johnson, S R; Mills, G B; Planeta, R J; Robert, A L; Marton, K; Messerly, B A; Puzovic, J; Bogomilov, M V; Bravar, A; Sgalaberna, D; Renfordt, R A E; Deveaux, M; Engel, R R; Grzeszczuk, A; Davis, N; Kuich, M; Lyubushkin, V; Igolkin, S; Kondratev, V; Kadija, K; Diakonos, F; Slodkowski, M A; Rauch, W H; Pistillo, C; Laszlo, A; Nakadaira, T; Hasegawa, T; Zambelli, L A; Sadovskiy, A; Morozov, S; Petukhov, O; Szuba, M K; Mathes, H; Herve, A E; Roehrich, D; Marino, A D; Wyszynski, O J; Grebieszkow, K; Wlodarczyk, Z; Rybczynski, M A; Wojtaszek-szwarc, A; Nirkko, M C; Sakashita, K; Golubeva, M; Kurepin, A; Manic, D; Kolev, D I; Kisiel, J E; Rondio, E; Larsen, D T; Czopowicz, T R; Seyboth, P; Turko, L; Guber, F; Marin, V; Busygina, O; Taranenko, A; Cirkovic, M; Ravonel salzgeber, M; Gazdzicki, M; Roth, M A; Pulawski, S M; Aduszkiewicz, A M; Bunyatov, S; Vechernin, V; Nagai, Y; Anticic, T; Dynowski, K M; Mackowiak-pawlowska, M K; Stefanek, G; Pavin, M; Fodor, Z P; Nishikawa, K; Tada, M; Kobayashi, T; Blondel, A P P; Hasler, A; Damyanova, A; Stroebele, H W; Rustamov, A; Posiadala, M Z; Kolesnikov, V; Andronov, E; Zimmerman, E D; Antoniou, N; Majka, Z; Veberic, D; Dumarchez, J; Naskret, M; Ivashkin, A; Tsenov, R V; Koziel, M G; Schmidt, K J; Melkumov, G; Popov, B; Panagiotou, A; Richter-was, E M; Ereditato, A; Paolone, V; Korzenev, A; Unger, M T; Wilczek, A G; Stepaniak, J M; Matulewicz, T N; Seryakov, A; Susa, T; Staszel, P P; Marcinek, A J; Brzychczyk, J; Maksiak, B; Tefelski, D B

    2007-01-01

    The NA61/SHINE (SHINE = SPS Heavy Ion and Neutrino Experiment) experiment is a large acceptance hadron spectrometer at the CERN SPS for the study of the hadronic final states produced in interactions of various beam particles (pions, protons, C, S and In) with a variety of fixed targets at the SPS energies. The main components of the current detector were constructed and used by the NA49 experiment. The physics program of NA61/SHINE consists of three main subjects. In the first stage of data taking (2007-2009) measurements of hadron production in hadron-nucleus interactions needed for neutrino (T2K) and cosmic-ray (Pierre Auger and KASCADE) experiments will be performed. In the second stage (2009-2011) hadron production in proton-proton and proton-nucleus interactions needed as reference data for a better understanding of nucleus-nucleus reactions will be studied. In the third stage (2009-2013) energy dependence of hadron production properties will be measured in nucleus-nucleus collisions as well as in p+p a...

  9. Coherent Pion Production in Neutrino Nucleus Scattering

    CERN Document Server

    Saraswat, Kapil; Kumar, Vineet; Singh, Venktesh

    2016-01-01

    In this article, we study the coherent pion production in neutrino-nucleus interaction in the resonance region using the formalism based on partially conserved axial current (PCAC) theorem which relates the neutrino-nucleus cross section to the pion-nucleus elastic cross section. The pion nucleus elastic cross section is calculated using the Glauber model in terms of pion-nucleon cross sections obtained by parameterizing the experimental data. We calculate the differential and integrated cross sections for charged current coherent pion production in neutrino carbon scattering. The results of integrated cross section calculations are compared with the measured data. Predictions for the differential and integrated cross sections for coherent pion productions in neutrino iron scattering using above formalism are also made.

  10. Parabrachial nucleus involvement in multiple system atrophy☆

    OpenAIRE

    Benarroch, E.E.; Schmeichel, A.M.; Low, P. A.; Parisi, J.E.

    2013-01-01

    Multiple system atrophy (MSA) is associated with respiratory dysfunction, including sleep apnea, respiratory dysrhythmia, and laryngeal stridor. Neurons of the parabrachial nucleus (PBN) control respiratory rhythmogenesis and airway resistance.

  11. Modified meson-nucleus optical potentials

    CERN Document Server

    Wilkin, C

    1973-01-01

    The author argues that the energy dependence of the meson-nucleus optical potential should be treated in a more dynamical fashion. When this is done, some of the difficulties found in phenomenological applications are eliminated. (13 refs).

  12. The nucleus in Finland - The second report

    International Nuclear Information System (INIS)

    The Finnish Nuclear Society (FNS) started the distribution of the Nucleus bulletin at the beginning of 1988. The volume of distribution has been extended since, including today nearly 1,000 persons. Both the English and the Finnish version of the bulletin is sent to various opinion leaders of society, i.e. the members of the parliament, ministries, the media, representatives of industry and other decision-makers of the energy field. After the five-year history of the Nucleus in Finland, it is time to look back and sum up the present status of the Nucleus. This report gives a short summary concerning the present distribution and its efficiency, the experiences gained and the influence of the bulletin in Finland. The first questionnaire was sent in November 1988, and the survey was repeated among the Finnish readers of the Nucleus in autumn 1992. The results of the latter survey are given in this report

  13. Testing string dynamics in lepton nucleus reactions

    International Nuclear Information System (INIS)

    The sensitivity of nuclear attenuation of 10-100 GeV lepton nucleus (ell A) reactions to space-time aspects of hadronization is investigated within the context of the Lund string model. We consider two mechanisms for attenuation in a nucleus: final state cascading and string flip excitations. Implications for the evolution of the energy density in nuclear collisions are discussed. 16 refs., 10 figs

  14. Information Processing in the Parabrachial Nucleus of the Pons: Temporal Relationships of Input and Output

    OpenAIRE

    Di Lorenzo, Patricia M.; Platt, Daniel; Victor, Jonathan D.

    2009-01-01

    As the second synapse in the central gustatory pathway of the rodent, the parabrachial nucleus of the pons (PbN) receives information about taste stimuli directly from the nucleus of the solitary tract (NTS). Data show that NTS cells amplify taste responses before transmitting taste-related signals to the PbN. NTS cells of varied response profiles send converging input to PbN cells, though input from NTS cells with similar profiles is more effective at driving PbN responses. PbN cells follow ...

  15. Sub-Arcsecond 2D Photometry and Spectrography of the Nucleus of M31 The Supermassive Black Hole Revisited

    CERN Document Server

    Bacon, R; Monnet, G; Nieto, J L

    1993-01-01

    Sub-arcsecond imagery (HRCAM, 0".35 - 0".57 FWHM) and two-dimensional spectrography (TIGER, 0".9 FWHM) of the central nucleus of M31 have been obtained at CFHT. The photometric data clearly show the double-peaked nucleus, in excellent agreement with a recent HST image by Lauer et al. 1993. We built deconvolved surface brightness models, using the multi-Gaussian expansion method. We then perform a detailed morphological analysis of the three central photometric components (bulge, nucleus and bright secondary peak) and derive various spatial luminosity models (oblate and triaxial). Stellar velocity and velocity dispersion fields were derived from the TIGER data: the former displays an extremely rapid rotation around the true center of the galaxy, while the latter exhibits a peaked structure offset in the opposite direction of the brightest light peak. Neglecting these offsets,both extended versions of the virial theorem and detailed hydrodynamical models confirm the classical strong central mass concentration, ...

  16. 3200 Phaethon, Asteroid or Comet Nucleus?

    Science.gov (United States)

    Boice, Daniel C.; Benkhoff, Johannes

    2015-08-01

    Physico-chemical modeling is central to understand the important physical processes in small solar system bodies. We have developed a computer simulation, SUISEI, that includes the physico-chemical processes relevant to comets within a global modeling framework. Our goals are to gain valuable insights into the intrinsic properties of cometary nuclei so we can better understand observations and in situ measurements. SUISEI includes a 3-D model of gas and heat transport in porous sub-surface layers in the interior of the nucleus.We present results on the application of SUISEI to the near-Sun object, Phaethon. Discovered in 1983 and classified as an asteroid, it has recently exhibited an active dust coma. Phaethon has long been associated as the source of the Geminids meteor shower so the dust activity provides a clear link to the meteor shower. The observed dust activity would traditionally lead to Phaethon being also classified as a comet (e.g., 2060-95P/Chiron, 133P/Elst-Pizarro). This is unusual since the orbit of Phaethon has a perihelion of 0.14 AU, resulting in surface temperatures of more than 1025K, much too hot for water ice or other volatiles to exist near the surface and drive the activity. This situation and others such as the “Active Asteroids” necessitates a revision of how we understand and classify these small asteroid-comet transition objects.We conclude the following for Phaethon:1. It is likely to contain relatively pristine volatiles in its interior despite repeated near perihelion passages of 0.14 AU during its history in its present orbit,2. Steady water gas fluxes at perihelion and throughout its orbit are insufficient to entrain the currently observed dust production,3. Thermal gradients into the surface as well as those caused by diurnal rotation are consistent with the mechanism of dust release due to thermal fracture,4. The initial large gas release during the first perihelion passage may be sufficient to produce enough dust to explain

  17. Observation of high energy gamma rays in intermediate energy nucleus-nucleus collisions

    NARCIS (Netherlands)

    Beard, K.B.; Benenson, W.; Bloch, C.; Kashy, E.; Stevenson, J.; Morrissey, D.J.; Plicht, J. van der; Sherrill, B.; Winfield, J.S.

    1985-01-01

    High energy electrons and positrons observed in medium energy nucleus-nucleus collisions are shown to be primarily due to the external conversion of high energy gamma rays. The reaction 14N+Cu was studied at E/A=40 MeV, and a magnetic spectrograph was used with a specially constructed multiwire prop

  18. Investigation of the (232)Th Nucleus Excitations at the FEL {gamma} - Nucleus Colliders

    CERN Document Server

    Koru, H; Sultansoy, S F; Sarer, B

    2001-01-01

    The physics search potential of the FEL {gamma} - Nucleus colliders is analysed using excitations of the (232)Th nucleus. It is shown that, due to the monochromacity of FEL {gamma} beam and high statistics, proposed colliders will play an important role in the field of "traditional" nuclear physics.

  19. Temperature measurement of quark-gluon plasma formed in high energy nucleus-nucleus collisions

    International Nuclear Information System (INIS)

    We discuss lepton pair and real photon emission from quark-gluon plasma, which is very likely to be formed in high energy nucleus-nucleus collisions. Measurement of pair production cross-section will provide one with accurate information of the temperature of this plasma. (author)

  20. Protein quality control in the nucleus.

    Science.gov (United States)

    Jones, Ramon D; Gardner, Richard G

    2016-06-01

    The nucleus is the repository for the eukaryotic cell's genetic blueprint, which must be protected from harm to ensure survival. Multiple quality control (QC) pathways operate in the nucleus to maintain the integrity of the DNA, the fidelity of the DNA code during replication, its transcription into mRNA, and the functional structure of the proteins that are required for DNA maintenance, mRNA transcription, and other important nuclear processes. Although we understand a great deal about DNA and RNA QC mechanisms, we know far less about nuclear protein quality control (PQC) mechanisms despite that fact that many human diseases are causally linked to protein misfolding in the nucleus. In this review, we discuss what is known about nuclear PQC and we highlight new questions that have emerged from recent developments in nuclear PQC studies. PMID:27015023

  1. An eccentric disk model for the nucleus of M31

    CERN Document Server

    Tremaine, S

    1995-01-01

    The nucleus of M31 may be a thick eccentric disk, composed of stars traveling on nearly Keplerian orbits around a black hole or other dark compact object. This hypothesis reproduces most of the features seen in HST photometry of the center of M31; in particular the bright off-center source P1 is the apoapsis of the disk. An eccentric disk can also explain the rotation curve and asymmetric dispersion profile revealed by ground-based observations. The central object must be smaller than 1 pc so that the potential felt by the disk is nearly Keplerian. The disk eccentricity may be excited by a secular instability driven by dynamical friction from the bulge.

  2. The suprachiasmatic nucleus: age-related decline in biological rhythms.

    Science.gov (United States)

    Nakamura, Takahiro J; Takasu, Nana N; Nakamura, Wataru

    2016-09-01

    Aging is associated with changes in sleep duration and quality, as well as increased rates of pathologic/disordered sleep. While several factors contribute to these changes, emerging research suggests that age-related changes in the mammalian central circadian clock within the suprachiasmatic nucleus (SCN) may be a key factor. Prior work from our group suggests that circadian output from the SCN declines because of aging. Furthermore, we have previously observed age-related infertility in female mice, caused by a mismatch between environmental light-dark cycles and the intrinsic, internal biological clocks. In this review, we address regulatory mechanisms underlying circadian rhythms in mammals and summarize recent literature describing the effects of aging on the circadian system. PMID:26915078

  3. Direct Photon Production in Proton-Nucleus and Nucleus-Nucleus Collisions

    CERN Document Server

    Cepila, J

    2011-01-01

    Prompt photons produced in a hard reaction are not accompanied with any final state interaction, either energy loss or absorption. Therefore, besides the Cronin enhancement at medium transverse momenta pT and small isotopic corrections at larger pT, one should not expect any nuclear effects. However, data from PHENIX experiment exhibit a significant large-pT suppression in central d+Au and Au+Au collisions that cannot be accompanied by coherent phenomena. We demonstrate that such an unexpected result is subject to the energy sharing problem near the kinematic limit and is universally induced by multiple initial state interactions. We describe production of photons in the color dipole approach and find a good agreement with available data in p+p collisions. Besides explanation of large-pT nuclear suppression at RHIC we present for the first time predictions for expected nuclear effects also in the LHC energy range at different rapidities. We include and analyze also a contribution of gluon shadowing as a leadi...

  4. Direct projection from the suprachiasmatic nucleus to hypophysiotrophic corticotropin-releasing factor immunoreactive cells in the paraventricular nucleus of the hypothalamus demonstrated...

    DEFF Research Database (Denmark)

    Vrang, N.; Larsen, P.J.; Mikkelsen, J.D.

    1995-01-01

    Suprachiasmatic nucleus, paraventricular nucleus, circadian rhythms, phaseolus vulgaris-leucoagglutinin, corticotropin-releasing factor, dual immunocytochemistry......Suprachiasmatic nucleus, paraventricular nucleus, circadian rhythms, phaseolus vulgaris-leucoagglutinin, corticotropin-releasing factor, dual immunocytochemistry...

  5. Nucleus-Nucleus Potential at Near-Barrier Energies from Self Consistent Calculations

    CERN Document Server

    Skalski, J

    2003-01-01

    We determine the static nucleus-nucleus potential from Hartree-Fock (HF) calculations with the Skyrme interaction. To this aim, HF equations are solved on a spatial mesh, with the initial configuration consisting of target and projectile positioned at various relative distances. For a number of reaction partners, the calculated barrier heights reasonably well compare with those extracted from the measured fusion and capture cross sections. At smaller target-projectile distances, our results show the intrinsic barriers to heavy compound nucleus formation. We speculate on their possible connection with the fusion hindrance observed for large Z sub T Z sub P.

  6. Inner Structure of Boiling Nucleus and Interfacial Energy Between Nucleus and Bulk Liquid

    Institute of Scientific and Technical Information of China (English)

    WANG Xiao-Dong; TIAN Yong; PENG Xiao-Feng; WANG Bu-Xuan

    2004-01-01

    @@ A model of two-region structure of a nucleus is proposed to describe nucleus evolution. The interfacial tension between bulk liquid phase and nucleus is dependent on the density gradient in the transition region and varies with the structure change of the transition region. With the interfacial tension calculated using this model, the predicted nucleation rate is very close to the experimental measurement. Furthermore, this model and associated analysis provide solid theoretical evidence to clarify the definition of nucleation rate and understand the nucleation phenomenon with insight into the physical nature.

  7. ULTRASTRUCTURE OF THE RAT MESENCEPHALIC TRIGEMINAL NUCLEUS

    NARCIS (Netherlands)

    LIEM, RSB; COPRAY, JCVM; VANWILLIGEN, JD

    1991-01-01

    The subcellular morphology of the mesencephalic trigeminal (Me5) nucleus in the rat was studied by transmission electron microscopy. Most neurons in the thin rostral as well as in the major caudal part of Me5 appeared as large (40-50-mu-m), round-to ovoid-shaped unipolar cells. A few neurons (estima

  8. An organism arises from every nucleus.

    Directory of Open Access Journals (Sweden)

    Nurullah Keklikoglu

    2009-12-01

    Full Text Available The fact that, cloning using somatic cell nuclear transfer (SCNT method has been performed, opened new horizons for cloning, and changed the way of our understanding and approach to cell and nucleus. The progress in cloning technology, brought the anticipation of the ability to clone an organism from each somatic cell nucleus. Therefore, the 'Cell Theory' is about to take the additional statement as "An organism arises from every nucleus". The development of gene targeting procedures which can be applied with SCNT, showed us that it may be possible to obtain different versions of the original genetic constitution of a cell. Because of this opportunity which is provided by SCNT, in reproductive cloning, it would be possible to clone enhanced organisms which can adapt to different environmental conditions and survive. Furthermore, regaining the genetic characteristics of ancestors or reverse herediter variations would be possible. On the other hand, in therapeutic cloning, more precise and easily obtainable alternatives for cell replacement therapy could be presented. However, while producing healthier or different organisms from a nucleus, it is hard to foresee the side effects influencing natural processes in long term is rather difficult.

  9. LSP-Nucleus Elastic Scattering Cross Sections

    OpenAIRE

    Vergados, J. D.; Kosmas, T. S.

    1997-01-01

    We calculate LSP-nucleus elastic scattering cross sections using some representative input in the restricted SUSY parameter space. The coherent matrix elements are computed throughout the periodic table while the spin matrix elements for the proposed $^{207}Pb$ target which has a rather simple nuclear structure. The results are compared to those given from other cold dark matter detection targets.

  10. Delta excitations in neutrino-nucleus scattering

    CERN Document Server

    Kim, H; Horowitz, C J; Kim, Hungchong

    1995-01-01

    We derive the contribution of \\Delta-h excitations to quasielastic charged-current neutrino-nucleus scattering in the framework of relativistic mean-field theory. We discuss the effect of \\Delta production on the determination of the axial mass M_A in neutrino scattering experiments.

  11. Inside a plant nucleus: discovering the proteins

    Czech Academy of Sciences Publication Activity Database

    Petrovská, Beáta; Šebela, M.; Doležel, Jaroslav

    2015-01-01

    Roč. 66, č. 6 (2015), s. 1627-1640. ISSN 0022-0957 R&D Projects: GA ČR(CZ) GA14-28443S; GA MŠk(CZ) LO1204 Institutional support: RVO:61389030 Keywords : Cell nucleus * chromatin * genome function Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 5.526, year: 2014

  12. TRPV1 Marks Synaptic Segregation of Multiple Convergent Afferents at the Rat Medial Solitary Tract Nucleus

    OpenAIRE

    Peters, James H.; McDougall, Stuart J.; Fawley, Jessica A.; Andresen, Michael C.

    2011-01-01

    TRPV1 receptors are expressed on most but not all central terminals of cranial visceral afferents in the caudal solitary tract nucleus (NTS). TRPV1 is associated with unmyelinated C-fiber afferents. Both TRPV1+ and TRPV1- afferents enter NTS but their precise organization remains poorly understood. In horizontal brainstem slices, we activated solitary tract (ST) afferents and recorded ST-evoked glutamatergic excitatory synaptic currents (ST-EPSCs) under whole cell voltage clamp conditions fro...

  13. Reward-dependent modulation of neuronal activity in the primate dorsal raphe nucleus

    OpenAIRE

    NAKAMURA, KAE; Matsumoto, Masayuki; Hikosaka, Okihide

    2008-01-01

    The dopamine system has been thought to play a central role in guiding behavior based on rewards. Recent pharmacological studies suggest that another monoamine neurotransmitter, serotonin, is also involved in reward processing. To elucidate the functional relationship between serotonin neurons and dopamine neurons, we performed single unit recording in the dorsal raphe nucleus (DRN), a major source of serotonin, and the substantia nigra pars compacta, a major source of dopamine, while monkeys...

  14. Nucleus accumbens neuronal activity in freely behaving rats is modulated following acute and chronic methylphenidate administration

    OpenAIRE

    Chong, Samuel L; Claussen, Catherine M; Dafny, Nachum

    2012-01-01

    Methylphenidate (MPD) is a psychostimulant that enhances dopaminergic neurotransmission in the central nervous system by using mechanisms similar to cocaine and amphetamine. The mode of action of brain circuitry responsible for an animal’s neuronal response to MPD is not fully understood. The nucleus accumbens (NAc) has been implicated in regulating the rewarding effects of psychostimulants. The present study used permanently implanted microelectrodes to investigate the acute and chronic effe...

  15. CHRONIC INTERMITTENT HYPOXIA AFFECTS INTEGRATION OF SENSORY INPUT BY NEURONS IN THE NUCLEUS TRACTUS SOLITARII

    OpenAIRE

    Kline, David D.

    2010-01-01

    The autonomic nervous and respiratory systems, as well as their coupling, adapt over a wide range of conditions. Chronic intermittent hypoxia (CIH) is a model for recurrent apneas and induces alterations in breathing and increases in sympathetic nerve activity which may ultimately result in hypertension if left untreated. These alterations are believed to be due to increases in the carotid body chemoreflex pathway. Here we present evidence that the nucleus tractus solitarii (nTS), the central...

  16. Glutamatergic transmission in the nucleus tractus solitarii: from server to peripherals in the cardiovascular information superhighway

    OpenAIRE

    Talman, W. T.

    1997-01-01

    Afferent nerves carrying signals from mechanoreceptors in the aortic arch and carotid sinus terminate predominantly in the nucleus tractus solitarii (NTS). Signal transduction and neurotransmission in the NTS are critical for central cardiovascular reflex control, but little was known about either until the late 1970's. None of the numerous neuroactive chemicals found in the NTS had met strict criteria as a neurotransmitter in the baroreflex arc until data suggested that the excitatory amino ...

  17. Differential effects of cardiac sympathetic afferent stimulation on neurons in the nucleus tractus solitarius

    OpenAIRE

    Wang, Wei-zhong; Gao, Lie; Pan, Yan-Xia; Zucker, Irving H.; Wang, Wei

    2006-01-01

    Activation of the cardiac “sympathetic afferent” reflex (CSAR) has been reported to depress the arterial baroreflex and enhance the arterial chemoreflex via a central mechanism. In the present study, we used single-unit extracellular recording techniques to examine the effects of stimulation of cardiac sympathetic afferents on baro- or chemosensitive neurons in the nucleus tractus solitarius (NTS) in anesthetized rats. Of 54 barosensitive NTS neurons tested for their response to epicardial ap...

  18. Brainstem nutrient sensing in the nucleus of the solitary tract inhibits feeding

    OpenAIRE

    Blouet, Clemence; Schwartz, Gary J.

    2012-01-01

    Direct detection of circulating nutrients by the central nervous system has been implicated in the regulation of energy balance, and the mediobasal hypothalamus is considered the primary sensing site mediating these effects. Neurons sensitive to energy-related signals have also been identified outside the hypothalamus, particularly within the caudomedial nucleus of the solitary tract (cmNTS) in brainstem, but the consequences of direct NTS nutrient detection on energy balance remain poorly ch...

  19. Functional Heterogeneity of Arcuate Nucleus Pro-Opiomelanocortin Neurons: Implications for Diverging Melanocortin Pathways

    OpenAIRE

    Sohn, Jong-Woo; Williams, Kevin W.

    2012-01-01

    Arcuate nucleus (ARC) pro-opiomelanocortin (POMC) neurons are essential regulators of food intake, energy expenditure, and glucose homeostasis. POMC neurons integrate several key metabolic signals that include neurotransmitters and hormones. The change in activity of POMC neurons is relayed to melanocortin receptors in distinct regions of the central nervous system. This review will summarize the role of leptin and serotonin receptors in regulating the activity of POMC neurons and provide a m...

  20. High-spin level structure of the neutron-rich nucleus 91Y

    CERN Document Server

    He, Xiao-Feng; Fang, Yong-De; Liu, Min-Liang; Zhang, Yu-Hu; Wang, Kai-Long; Wang, Jian-Guo; Guo, Song; Qiang, Yun-Hua; Zheng, Yong; Zhang, Ning-Tao; Li, Guang-Shun; Gao, Bing-Shui; Wu, Xiao-Guang; He, Chuang-Ye; Zheng, Yun

    2015-01-01

    High-spin level structure of the neutron-rich nucleus 91Y has been reinvestigated via the 82Se(13C, p3n)91Y reaction. A newly constructed level scheme including several key levels clarifies the uncertainties in the earlier studies. These levels are characterized by the breaking of the Z=38 and N=56 subshell closures, which involves in the spin-isospin dependent central force and tensor force.

  1. Diversity among principal and GABAergic neurons of the anterior olfactory nucleus

    OpenAIRE

    KAY, RACHEL B.; Brunjes, Peter C

    2014-01-01

    Understanding the cellular components of neural circuits is an essential step in discerning regional function. The anterior olfactory nucleus (AON) is reciprocally connected to both the ipsi- and contralateral olfactory bulb (OB) and piriform cortex (PC), and, as a result, can broadly influence the central processing of odor information. While both the AON and PC are simple cortical structures, the regions differ in many ways including their general organization, internal wiring and synaptic ...

  2. Adiponectin Depolarizes Parvocellular Paraventricular Nucleus Neurons Controlling Neuroendocrine and Autonomic Function

    OpenAIRE

    Hoyda, Ted Donald; Samson, Willis Kendrick; Ferguson, Alastair Victor

    2008-01-01

    Adiponectin plays important roles in the control of energy homeostasis and autonomic function through peripheral and central nervous system actions. The paraventricular nucleus (PVN) of the hypothalamus is a primary site of neuroendocrine (NE) and autonomic integration, and, thus, a potential target for adiponectin actions. Here, we investigate actions of adiponectin on parvocellular PVN neurons. Adiponectin influenced the majority (65%) of parvocellular PVN neurons, depolarizing 47%, whereas...

  3. The Crime of Rape under the Rome Statute of the ICC (with a special emphasis on the jurisprudence of the Ad Hoc Criminal Tribunals

    Directory of Open Access Journals (Sweden)

    Nicole Brigitte Maier

    2011-05-01

    Full Text Available

    This article delivers insight into the purposes and intentions of committing rape within wartimes, its victims, its perpetrators, and, finally, under which circumstances the crime of rape is punishable as a crime against humanity.

    In the first part a definition on crime of rape is given, in this regard relevant literature and case law of both the Yugoslavia Tribunal and the Tribunal of Rwanda will be referred to. On the topics of victims, perpetrators and purposes related literature in the field of psychology, criminology and medical science will be taken into consideration. The discussion on the link between rape and the crime against humanity will focus on relevant cases, judgments and reports, largely of the ICC, the ICTY and the ICTR.

  4. Nucleon molecular orbitals and the transition mechanism between molecular orbitals in nucleus-nucleus collisions

    International Nuclear Information System (INIS)

    The molecular orbitals of the nucleon(s) in nucleus-nucleus collisions are dynamically defined as a linear combination of nucleon single-particle orbits (LCNO) in a rotating frame by using the coupled-reaction-channel (CRC) theory. Nucleon molecular orbitals and the promotions of nucleon, - especially due to the Landau-Zener radial coupling are discussed with the method above mentioned. (author)

  5. Random matrix theory and analysis of nucleus-nucleus collisions at high energies

    International Nuclear Information System (INIS)

    We propose a novel method for analysis of experimental data obtained at relativistic nucleus-nucleus collisions. The method, based on the ideas of Random Matrix Theory (RMT) is applied to detect systematic errors that occur at measurements of momentum distributions of emitted particles. The unfolded momentum distribution is well described by the Gaussian orthogonal ensemble of random matrices, when the uncertainty in the momentum distribution is maximal. The method is free from unwanted background contributions

  6. Transverse energy distributions in nucleus-nucleus collisions at 200 GeV/nucleon

    International Nuclear Information System (INIS)

    The transverse energy ET distributions of nucleus-nucleus collisions are studied in the framework of a simple geometrical model. The distributions for inclusive production of J/ψ and muon pairs in the mass continuum are analyzed. The shape of the ET distribution of the continuum agrees with the model. The previously observed decrease of the ratio (J/ψ)/continuum with increasing ET is due to the behavior of the J/ψ. (orig.)

  7. Study of -nucleus interaction through the formation of -nucleus bound state

    Indian Academy of Sciences (India)

    V Jha; B J Roy; A Chatterjee; H Machner

    2006-05-01

    The question of possible existence of -mesic nuclei is quite intriguing. Answer to this question will deeply enrich our understanding of -nucleus interaction which is not so well-understood. We review the experimental efforts for the search of -mesic nuclei and describe the physics motivation behind it. We present the description of an experiment for the search of -nucleus bound state using the GeV proton beam, currently being performed at COSY.

  8. Hypoxia activates nucleus tractus solitarii neurons projecting to the paraventricular nucleus of the hypothalamus

    OpenAIRE

    King, T. Luise; Heesch, Cheryl M.; Clark, Catharine G.; Kline, David D.; Hasser, Eileen M.

    2012-01-01

    Peripheral chemoreceptor afferent information is sent to the nucleus tractus solitarii (nTS), integrated, and relayed to other brain regions to alter cardiorespiratory function. The nTS projects to the hypothalamic paraventricular nucleus (PVN), but activation and phenotype of these projections during chemoreflex stimulation is unknown. We hypothesized that activation of PVN-projecting nTS neurons occurs primarily at high intensities of hypoxia. We assessed ventilation and cardiovascular para...

  9. Systematic investigation of scaled factorial cumulant moments for nucleus-nucleus interactions

    International Nuclear Information System (INIS)

    We use scaled factorial cumulant moments to analyze pseudorapidity fluctuations in nucleus-nucleus collisions. This approach is similar to the method of scaled factorial moments except that it removes the effects of lower-order correlations upon a given moment. Significant second-order cumulants and cumulant indices (slopes with respect to bin size) are found for all of the interactions studied. These indices are found to have an inverse dependence upon average pseudorapidity particle density

  10. Fusion cross sections for reactions involving medium & heavy nucleus-nucleus systems

    OpenAIRE

    Atta, Debasis; Basu, D. N.

    2014-01-01

    Existing data on near-barrier fusion excitation functions of medium and heavy nucleus-nucleus systems have been analyzed using a simple diffused barrier formula derived assuming the Gaussian shape of the barrier height distributions. Fusion cross section is obtained by folding the Gaussian barrier distribution with the classical expression for the fusion cross section for a fixed barrier. The energy dependence of the fusion cross section, thus obtained, provides good description to the existi...

  11. The supermassive black hole and double nucleus of the core elliptical NGC5419

    CERN Document Server

    Mazzalay, X; Saglia, R P; Wegner, G A; Bender, R; Erwin, P; Fabricius, M H; Rusli, S

    2016-01-01

    We obtained adaptive-optics assisted SINFONI observations of the central regions of the giant elliptical galaxy NGC5419 with a spatial resolution of 0.2 arcsec ($\\approx 55$ pc). NGC5419 has a large depleted stellar core with a radius of 1.58 arcsec (430 pc). HST and SINFONI images show a point source located at the galaxy's photocentre, which is likely associated with the low-luminosity AGN previously detected in NGC5419. Both the HST and SINFONI images also show a second nucleus, off-centred by 0.25 arcsec ($\\approx 70$ pc). Outside of the central double nucleus, we measure an almost constant velocity dispersion of $\\sigma \\sim 350$ km/s. In the region where the double nucleus is located, the dispersion rises steeply to a peak value of $\\sim 420$ km/s. In addition to the SINFONI data, we also obtained stellar kinematics at larger radii from the South African Large Telescope. While NGC5419 shows low rotation ($v < 50$ km/s), the central regions (inside $\\sim 4 \\, r_b$) clearly rotate in the opposite direc...

  12. A deep Chandra observation of the active galactic nucleus outburst and merger in Hickson compact group 62

    NARCIS (Netherlands)

    D.A. Rafferty; L. Bîrzan; P.E.J. Nulsen; B.R. McNamara; W.N. Brandt; M.W. Wise; H.J.A. Röttgering

    2013-01-01

    We report on an analysis of new Chandra data of the galaxy group HCG 62, well known for possessing cavities in its intragroup medium (IGM) that were inflated by the radio lobes of its central active galactic nucleus (AGN). With the new data, a factor of 3 deeper than previous Chandra data, we re-exa

  13. Neuropeptide expression in the human trigeminal nucleus caudalis and in the cervical spinal cord C1 and C2

    DEFF Research Database (Denmark)

    Uddman, R; Tajti, J; Hou, M;

    2002-01-01

    In migraine and other primary headaches there is a strong vascular component. Besides the trigeminovascular components some of the associated symptoms point to the involvement of brain stem regions. The central limb of the trigeminal vascular pathway is its projection to the trigeminal nucleus ca...

  14. The Baryon Production and Baryon Number Transfer in Hadron-Hadron, Hadron-Nucleus and Nucleus-Nucleus Collisions

    International Nuclear Information System (INIS)

    This work concerns soft hadronic interactions which in the Standard Model carry most of the observable cross-section but are not amenable to quantitative predictions due to the very nature of the QCD (Theory of Strong Interactions). In the low momentum transfer region the evolving coupling constant caused perturbation theory to break down. In this situation better experimental understanding of the physics phenomena is needed. One aspect of the soft hadronic interactions will be discussed in this work: transfer of the baryon number from the initial to the final state of the interaction. The past experimental knowledge on this process is presented, reasons for its unsatisfactory status are discussed and condition necessary for improvement are outlined: that is experimental apparatus with superior performance over the full range of available interactions: hadron-hadron collision, hadron-nucleus and nucleus-nucleus interactions. A consistent model-independent picture of the baryon number transfer process emerging from the data on the full range of interactions is shown. It offers serious challenge to theory to provide quantitative and detailed explanation of the measurements. (author)

  15. Transverse momentum spectra in high-energy nucleus-nucleus, proton-nucleus and proton-proton collisions

    Institute of Scientific and Technical Information of China (English)

    XIE Wen-Jie

    2011-01-01

    The transverse momentum distributions of final-state particles produced in nucleus-nucleus (AA),proton-nucleus (pA),and proton-proton (pp) collisions at high energies are investigated using a multisource ideal gas model.Our calculated results show that the contribution of hard emission can be neglected in the study of transverse momentum spectra of charged pions and kaons produced in Cu-Cu collisions at (√SNN)=22.5 GeV.And if we consider the contribution of hard emission,the transverse momentum spectra of p and (P) produced in Cu-Cu collisions at (√SNN)=22.5 GeV,KsO produced in Pb-Pb collisions at 158 A GeV,J/ψ particles produced in p-Pb collisions at 400 GeV and π+,K+,p produced in proton-proton collisions at (√S)=200 GeV,can be described by the model,especially in the tail part of spectra.

  16. Centrally administered glucagon stimulates sympathetic nerve activity in rat.

    Science.gov (United States)

    Krzeski, R; Czyzyk-Krzeska, M F; Trzebski, A; Millhorn, D E

    1989-12-18

    The effect of pancreatic glucagon given intravenously, intracerebroventricularly and microinjected into the nucleus of the solitary tract on sympathetic activity in the cervical trunk and adrenal nerve was examined in rat. In each case glucagon caused a relatively long-lasting substantial increase in discharge of both nerves. This finding shows that glucagon can act centrally to stimulate sympathetic activity. The most probable site for the sympathoexcitatory effect of glucagon is the nucleus of the solitary tract. PMID:2598031

  17. MR findings of degenerative changes of nucleus pulposus in lumbar spine: sequential changes after disc herniation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sang Joon [Choong-Ang Gil Hospital, Seoul (Korea, Republic of); Cha, Yoo Mi; Hwang, Hee Young [College of Medicine, Dankook University, Chenoan (Korea, Republic of)

    1994-04-15

    To evaluate the relationship between MR changes of the nucleus pulposus and the time interval after traumatic disc herniation. T2-weighted MR images of 132 patients with back pain and/or sciatica were reviewed. The changes of signal intensity, central cleft and height of the nucleus pulposus were used as criteria of disc degeneration and they were graded as normal, mild, moderate and severe degree of degeneration. Putting these criteria together we provided integrated grade of degeneration of the nucleus pulposus(grade 0-3). To get the preliminary data for normal and age-related disc degeneration, we measured the disc height by age groups and disc levels and analyzed the relationship between the age of the patients and the signal intensity, cleft and height in normal disc levels of the 132 patients. In 68 patients of 88 levels disc herniation, we analyzed the relationship between symptom duration and the degree of degeneration. Among these 68 patients we selected 14 patients(16 levels) who were under 30 years of age and had history of recent trauma to minimize data distortion from age related degeneration and ambiguity of initiation point of degeneration. In this group we analyzed the relationship between the time period after traumatic disc herniation and the degree of degeneration. The age of the patient had close relationship with the grade of signal intensity, central cleft, and disc height and grade of degeneration of the nucleus pulposus in normal discs. In 88 levels of herniated discs, the duration of symptom and degree of degeneration showed moderate correlation. In 14 patients of disc herniation who were under 30 years old and had trauma history in recent 2 years, grade 1 disc degeneration occurred in average 3.7 months after trauma. Although it was difficult to proceed statistical analysis in the last group because of small patients number, the degree of degeneration of nucleus pulposus had close relationship with the duration after traumas or duration of

  18. Protein quality control in the nucleus

    DEFF Research Database (Denmark)

    Nielsen, Sofie V.; Poulsen, Esben Guldahl; Rebula, Caio A.;

    2014-01-01

    to aggregate, cells have evolved several elaborate quality control systems to deal with these potentially toxic proteins. First, various molecular chaperones will seize the misfolded protein and either attempt to refold the protein or target it for degradation via the ubiquitin-proteasome system. The...... particularly active in protein quality control. Thus, specific ubiquitin-protein ligases located in the nucleus, target not only misfolded nuclear proteins, but also various misfolded cytosolic proteins which are transported to the nucleus prior to their degradation. In comparison, much less is known about...... these mechanisms in mammalian cells. Here we highlight recent advances in our understanding of nuclear protein quality control, in particular regarding substrate recognition and proteasomal degradation....

  19. Nuclear effects in neutrino-nucleus DIS

    CERN Document Server

    Hirai, M; Saitô, K

    2009-01-01

    We explain the current status of nuclear parton distribution functions in connection with neutrino-nucleus interactions. Neutrino deep inelastic scattering (DIS) measurements have been done for heavy nuclear targets such as iron and lead. In order to extract structure functions of the nucleon, one needs to remove nuclear effects from the data. However, recent studies indicate that there are inconsistencies in nuclear modifications between charged-lepton and neutrino scattering measurements. Nuclear medium effects could be also an origin for the NuTeV anomaly in the weak-mixing angle. In addition, the modifications could affect neutrino-oscillation experiments because some DIS events of neutrino-oxygen nucleus interactions are contained. On the other hand, the nuclear medium effects themselves are interesting and important for describing nuclei in terms of quark and gluon degrees of freedom.

  20. Correlations in neutrino-nucleus scattering

    CERN Document Server

    Van Cuyck, Tom; Jachowicz, Natalie; González-Jiménez, Raul; Martini, Marco; Ryckebusch, Jan; Van Dessel, Nils

    2016-01-01

    We present a detailed study of charged-current quasielastic neutrino-nucleus scattering and of the influence of correlations on one- and two-nucleon knockout processes. The quasielastic neutrino-nucleus scattering cross sections, including the influence of long-range correlations, are evaluated within a continuum random phase approximation approach. The short-range correlation formalism is implemented in the impulse approximation by shifting the complexity induced by the correlations from the wave functions to the operators. The model is validated by confronting $(e,e^\\prime)$ cross-section predictions with electron scattering data in the kinematic region where the quasielastic channel is expected to dominate. Further, the $^{12}$C$(\

  1. Coherency in Neutrino-Nucleus Elastic Scattering

    CERN Document Server

    Kerman, S; Deniz, M; Wong, H T; Chen, J -W; Li, H B; Lin, S T; Liu, C -P; Yue, Q

    2016-01-01

    Neutrino-nucleus elastic scattering provides a unique laboratory to study the quantum mechanical coherency effects in electroweak interactions, towards which several experimental programs are being actively pursued. We report results of our quantitative studies on the transitions towards decoherency. A parameter ($\\alpha$) is identified to describe the degree of coherency, and its variations with incoming neutrino energy, detector threshold and target nucleus are studied. The ranges of $\\alpha$ which can be probed with realistic neutrino experiments are derived, indicating complementarity between projects with different sources and targets. Uncertainties in nuclear physics and in $\\alpha$ would constrain sensitivities in probing physics beyond the standard model. The maximum neutrino energies corresponding to $\\alpha$>0.95 are derived.

  2. Coherency in neutrino-nucleus elastic scattering

    Science.gov (United States)

    Kerman, S.; Sharma, V.; Deniz, M.; Wong, H. T.; Chen, J.-W.; Li, H. B.; Lin, S. T.; Liu, C.-P.; Yue, Q.; Texono Collaboration

    2016-06-01

    Neutrino-nucleus elastic scattering provides a unique laboratory to study the quantum mechanical coherency effects in electroweak interactions, towards which several experimental programs are being actively pursued. We report results of our quantitative studies on the transitions towards decoherency. A parameter (α ) is identified to describe the degree of coherency, and its variations with incoming neutrino energy, detector threshold, and target nucleus are studied. The ranges of α that can be probed with realistic neutrino experiments are derived, indicating complementarity between projects with different sources and targets. Uncertainties in nuclear physics and in α would constrain sensitivities in probing physics beyond the standard model. The maximum neutrino energies corresponding to α >0.95 are derived.

  3. Nickel-48, a very magic nucleus

    International Nuclear Information System (INIS)

    Ni48, which is doubly magic and very exotic, has been observed in an experiment performed at the GANIL accelerator. This nucleus, which is composed of 20 neutrons and 28 protons, is the most neutron-deficient nucleus that can be obtained, its decay mode has not yet been determined but theory predicts a 2-proton emission. Ni48 nuclei were obtained when accelerated (75 MeV/A) Ni58 ions had undergone fragmentation on natural nickel target. During this experiment 4 nuclei of Ni48 were produced as well as other very exotic nuclei: 90 nuclei of Ni49, 50 of Fe45 and 290 of Cr42. This experiment lasted 10 days and 1017 Ni58 ions were projected on the target. (A.C.)

  4. Hadron production in the nucleus fragmentation region

    International Nuclear Information System (INIS)

    The RHIC hadron production data in hadronic collisions at the forward rapidities may hint the evidence of the Color Glass Condensate (CGC). However, in the opposite region, backward rapidities, new effects should be important in order to describe the observables. In this work, the charged hadron and π0 productions are investigated in the fragmentation region of the nucleus (backward rapidities) considering dAu and pp collisions in the context of the Color Glass Condensate. In the backward rapidity region, only the proton can be treated as a CGC, and the large x nuclear effects need to be considered in order to describe the cross section. The results are shown by means of the nuclear modification ratio comparing the proton-nucleus and proton-proton cross sections and such ratio presents some dependences on the large x nuclear effects. (author)

  5. Nucleus spectroscopy: extreme masses and deformations

    International Nuclear Information System (INIS)

    The author proposes a synthesis of research activities performed since 1995 in the field of experimental nuclear physics, and more particularly in the investigation of two nucleus extreme states: deformation on the one hand, heavy and very heavy nuclei on the other hand. After a presentation of the context of investigations on deformation, rotation, and heavy nuclei, he gives an overview of developments regarding instruments (gamma spectrometers, detection of fission fragments, and detection at the focal plane of spectrometers or separators) and analysis techniques. Experiments and results are then reported and discussed, concerning super-deformed states with a high angular moment, spectroscopy of neutron-rich nuclei, very heavy nuclei close to nucleus map borders. He finally draws perspectives for middle and long term studies on the heaviest nuclei

  6. Dropped nucleus following phacoemulsification cataract surgery.

    Science.gov (United States)

    Tajunisah, I; Reddy, S C

    2007-12-01

    Twenty two cases of dropped nucleus following 1,196 phacoemulsification procedures in cataract surgery were examined retrospectively to determine the incidence, predisposing factors and visual outcomes of this dreaded complication. All the cases underwent pars plana vitrectomy and the lens fragments were removed with phacofragmotome, vitrectomy cutter or delivered through limbus. The incidence of dropped nucleus was 1.84%. The predisposing factors were hard cataracts (13.6%), polar cataracts (9.1%), previously vitrectomized eyes (4.5%) and high myopia (4.5%). The final visual outcome was > or = 6/12 in 10 eyes (45.5%); complications were seen in 5 eyes (22.7%). The interval between initial surgery and vitrectomy, the method of fragment removal and the type of lens implanted, did not influence the final visual outcome. PMID:18705466

  7. The fast Ice Nucleus chamber FINCH

    Science.gov (United States)

    Bundke, U.; Nillius, B.; Jaenicke, R.; Wetter, T.; Klein, H.; Bingemer, H.

    2008-11-01

    We present first results of our new developed Ice Nucleus (IN) counter FINCH from the sixth Cloud and Aerosol Characterization Experiment (CLACE 6) campaign at Jungfraujoch station, 3571 m asl. Measurements were made at the total and the ICE CVI inlet. Laboratory measurements of ice onset temperatures by FINCH are compared to those of the static diffusion chamber FRIDGE (FRankfurt Ice Deposition Freezing Experiment). Within the errors of both new instruments the results compare well to published data.

  8. Development of a Mobile Ice Nucleus Counter

    Energy Technology Data Exchange (ETDEWEB)

    Kok, Gregory; Kulkarni, Gourihar

    2014-07-10

    An ice nucleus counter has been constructed. The instrument uses built-in refrigeration systems for wall cooling. A cascade refrigeration system will allow the cold wall to operate as low as -70 deg C, and a single stage system can operate the warm wall at -45 deg C. A unique optical particle counter has been constructed using polarization detection of the scattered light. This allows differentiation of the particles exiting the chamber to determine if they are ice or liquid.

  9. Control of nucleus accumbens activity with neurofeedback

    OpenAIRE

    Greer, Stephanie M.; Trujillo, Andrew J.; Glover, Gary H.; Knutson, Brian

    2014-01-01

    The nucleus accumbens (NAcc) plays critical roles in healthy motivation and learning, as well as in psychiatric disorders (including schizophrenia and attention deficit hyperactivity disorder). Thus, techniques that confer control of NAcc activity might inspire new therapeutic interventions. By providing second-to-second temporal resolution of activity in small subcortical regions, functional magnetic resonance imaging (fMRI) can resolve online changes in NAcc activity, which can then be pres...

  10. Neutrino-nucleus reactions in supernovae

    Directory of Open Access Journals (Sweden)

    Dzhioev Alan A.

    2016-01-01

    Full Text Available We study thermal effects on neutrino-nucleus reactions occurring under supernova conditions. The approach we use is based on the QRPA extended to finite temperature by the thermofield dynamics formalism. For the relevant supernova conditions we calculate inelastic neutrino scattering and neutrino absorption cross sections for two sample nuclei, 56Fe and 82Ge. In addition, we apply the approach to examine the rate of neutrino-antineutrino pair emission by hot nuclei.

  11. Radiative corrections to pion-nucleus bremsstrahlung

    OpenAIRE

    Kaiser, N.(Physik Department T39, Technische Universität München, Garching, D-85747, Germany); Friedrich, J. M.

    2008-01-01

    We calculate the one-photon loop radiative corrections to virtual pion Compton scattering $\\pi^- \\gamma^* \\to \\pi^- \\gamma$, that subprocess which determines in the one-photon exchange approximation the pion-nucleus bremsstrahlung reaction $\\pi^- Z\\to \\pi^- Z \\gamma$. Ultraviolet and infrared divergencies of the loop integrals are both treated by dimensional regularization. Analytical expressions for the ${\\cal O}(\\alpha)$ corrections to the virtual Compton scattering amplitudes, $A(s,u,Q)$ a...

  12. Core nucleus polarization in Λ hypernuclei

    International Nuclear Information System (INIS)

    The response of the core nucleus to the Λ in a hypernucleus is studied with a local density approximation. This reproduces the energies and radii of the core nuclei as well as the Λ-single particle (s.p.) energies quite well. The polarizing effect of the Λ depends on the core response through an 'effective' compression modulus KA of the nucleus. For a certain class of energy functional, KA is found to be almost independent of the compression modulus K of the infinite nuclear matter. This indeed is a surprising result, and varies with the Hartree-Fock calculations with effective interactions. Reasons for this discrepancy are carefully examined. We consider values of K in the range ≅100-400 MeV. Furthermore, the polarizing effects also depend critically on D(ρ), the Λ binding in nuclear matter at density ρ. For only a direct ΛN force: D∝ρ and the core nucleus contracts giving rise to relatively larger core polarization. However, for a ''saturating'' D(ρ) (with a maximum at ρm0, where ρ0 is the nuclear matter equilibrium density), which is required to fit the s.p. data, the s-shell hypernuclei binding energies and the low energy Λp scattering data, which results from a ΛN force (including exchange) and ΛNN forces, there may be an expansion of the nucleus with nucleons flowing from the interior to the surface. This is shown to reduce the core polarization effects substantially (for ρm in the neighborhood of ρ0). The resulting changes in root mean square radius and core energy depend on A, but are mostly very small, justifying their general neglect

  13. Efficient nucleus detector in histopathology images.

    Science.gov (United States)

    Vink, J P; Van Leeuwen, M B; Van Deurzen, C H M; De Haan, G

    2013-02-01

    In traditional cancer diagnosis, (histo)pathological images of biopsy samples are visually analysed by pathologists. However, this judgment is subjective and leads to variability among pathologists. Digital scanners may enable automated objective assessment, improved quality and reduced throughput time. Nucleus detection is seen as the corner stone for a range of applications in automated assessment of (histo)pathological images. In this paper, we propose an efficient nucleus detector designed with machine learning. We applied colour deconvolution to reconstruct each applied stain. Next, we constructed a large feature set and modified AdaBoost to create two detectors, focused on different characteristics in appearance of nuclei. The proposed modification of AdaBoost enables inclusion of the computational cost of each feature during selection, thus improving the computational efficiency of the resulting detectors. The outputs of the two detectors are merged by a globally optimal active contour algorithm to refine the border of the detected nuclei. With a detection rate of 95% (on average 58 incorrectly found objects per field-of-view) based on 51 field-of-view images of Her2 immunohistochemistry stained breast tissue and a complete analysis in 1 s per field-of-view, our nucleus detector shows good performance and could enable a range of applications in automated assessment of (histo)pathological images. PMID:23252774

  14. The nucleus basalis in Huntington's disease.

    Science.gov (United States)

    Clark, A W; Parhad, I M; Folstein, S E; Whitehouse, P J; Hedreen, J C; Price, D L; Chase, G A

    1983-10-01

    The nucleus basalis of Meynert (nbM) provides most of the cholinergic input to the cerebral cortex. The loss of cortical choline acetyltransferase (CAT) activity in Alzheimer's disease (AD) and senile dementia of the Alzheimer's type (SDAT) appears to be related to a severe depopulation of the nbM in this dementia. In Huntington's disease (HD), by contrast, there is no loss of cortical CAT activity. The present quantitative study indicates that (1) there is no significant loss of neurons from the nbM in HD, and (2) that the previously described cytologic changes in the neurons of this nucleus in HD patients do not differ significantly from controls. These findings are consistent with the working hypothesis that the types of dementia associated with reductions of neocortical CAT activity are characterized by dysfunction or death of neurons in the nbM, but dementing disorders with normal neocortical CAT activity manifest no major abnormalities in this cholinergic nucleus of the basal forebrain. PMID:6225032

  15. The INTEGRAL View of the Galactic Nucleus

    CERN Document Server

    Goldwurm, A; Goldoni, P; Paul, J; Terrier, R; Falanga, M; Ubertini, P; Bazzano, A; Santo, M D; Winkler, C; Parmar, A N; Kuulkers, E; Ebisawa, K; Roques, J P; Skinner, G K; Lund, N; Melia, F; Yusef-Zadeh, F

    2004-01-01

    We present the preliminary results of the observational campaign performed in 2003 to study the Galactic Nucleus with INTEGRAL. The mosaicked images obtained with the IBIS/ISGRI coded aperture instrument in the energy range above 20 keV, give a yet unseen view of the high-energy sources of this region in hard X and gamma-rays, with an angular resolution of 12'. We report on the discovery of a source, IGR J17456-2901, compatible with the instrument's point spread function and coincident with the Galactic Nucleus Sgr A* to within 0.9'. The source is visible up to 60-80 keV with a 20-100 keV luminosity at 8 kpc of 3 x 10E35 erg/s. Although we cannot unequivocally associate the new INTEGRAL source to the Galactic Nucleus, this is the first report of significant hard X-ray emission from within the inner 10' of the Galaxy and a contribution from the galactic center supermassive black hole itself cannot be excluded. Here we discuss the results obtained and the perspectives for future observations of the Galactic Nuc...

  16. Actomyosin contractility rotates the cell nucleus

    CERN Document Server

    Kumar, Abhishek; Sumit, Madhuresh; Ramaswamy, Sriram; Shivashankar, G V

    2013-01-01

    The nucleus of the eukaryotic cell functions amidst active cytoskeletal filaments, but its response to the stresses carried by these filaments is largely unexplored. We report here the results of studies of the translational and rotational dynamics of the nuclei of single fibroblast cells, with the effects of cell migration suppressed by plating onto fibronectin-coated micro-fabricated patterns. Patterns of the same area but different shapes and/or aspect ratio were used to study the effect of cell geometry on the dynamics. On circles, squares and equilateral triangles, the nucleus undergoes persistent rotational motion, while on high-aspect-ratio rectangles of the same area it moves only back and forth. The circle and the triangle showed respectively the largest and the smallest angular speed. We show that our observations can be understood through a hydrodynamic approach in which the nucleus is treated as a highly viscous inclusion residing in a less viscous fluid of orientable filaments endowed with active...

  17. Effect of aqueous extract of Drosera Spatulata on firing rate of paragigantocellularis nucleus neurons after pain induction by formalin in rats

    OpenAIRE

    Sahar Golabi; majid hassanpour-ezati; Kambiz Rohampour

    2010-01-01

    Introduction: Previously, we demonstrated that i.p. injection of aqueous extract prepared from aerial parts of Drosera Spatulata (Droseraceae) can induced remarkable analgesia in both phases of formalin test in rats. Because, analgesia induced in acute phase of formalin test mainly mediated by activation of central analgesic mechanisms and also paragigantocellularis (PGi) nucleus is part of brain descending pain control systems; the role of this nucleus in analgesic action of the extract on a...

  18. Intrinsic properties and neuropharmacology of midline paraventricular thalamic nucleus neurons.

    Directory of Open Access Journals (Sweden)

    Miloslav Kolaj

    2014-04-01

    Full Text Available Neurons in the midline and intralaminar thalamic nuclei are components of an interconnected brainstem, limbic and prefrontal cortex neural network that is engaged during arousal, vigilance, motivated and addictive behaviors, and stress. To better understand the cellular mechanisms underlying these functions, here we review some of the recently characterized electrophysiological and neuropharmacological properties of neurons in the paraventricular thalamic nucleus (PVT, derived from whole cell patch clamp recordings in acute rat brain slice preparations. PVT neurons display firing patterns and ionic conductances (IT and IH that exhibit significant diurnal change. Their resting membrane potential is maintained by various ionic conductances that include inward rectifier (Kir, hyperpolarization-activated nonselective cation (HCN and TWIK-related acid sensitive (TASK K+ channels. Firing patterns are regulated by high voltage-activated (HVA and low voltage-activated (LVA Ca2+ conductances. Moreover, transient receptor potential (TRP-like nonselective cation channels together with Ca2+- and Na+-activated K+ conductances (KCa; KNa contribute to unique slow afterhyperpolarizing potentials (sAHPs that are generally not detectable in lateral thalamic or reticular thalamic nucleus neurons. We also report on receptor-mediated actions of GABA, glutamate, monoamines and several neuropeptides: arginine vasopressin, gastrin-releasing peptide, thyrotropin releasing hormone and the orexins (hypocretins. This review represents an initial survey of intrinsic and transmitter-sensitive ionic conductances that are deemed to be unique to this population of midline thalamic neurons, information that is fundamental to an appreciation of the role these thalamic neurons may play in normal central nervous system (CNS physiology and in CNS disorders that involve the dorsomedial thalamus.

  19. Embryonic and larval development of the sonic motor nucleus in the oyster toadfish

    International Nuclear Information System (INIS)

    The sonic motor nucleus (SMN), a likely homologue of the hypoglossal nucleus, provides the final common pathway for sound production in the oyster toadfish (Opsanus tau). SMN neurons increase in size and number for 7-8 years postnatally, and the swimbladder-sonic muscle complex grows throughout life. This study describes the normal embryonic and larval development of the SMN from its initial differentiation on about day 19 through day 40, when the yolk sac is resorbed and the fish is free swimming. In contrast to the rapid development of CNS nuclei in mammals, the SMN gradually increased in maturity with more active growth at the beginning and end of the observation period and a relatively static period in the middle. Consistent with a hypoglossal homology, the SMN differentiated within the spinal cord, added cells rostrally, and eventually extended into the medulla. Immature neurons appeared to originate from precursor cells in the ventral portion of the ventricular zone of the central canal. Such cells were initially round with little cytoplasmic development and later added processes and Nissl substance. The number of neurons increased 10-fold from a median of 35 to 322 cells, and no evidence of cell death was observed. Soma area approximately doubled from 20.6 to 41.2 micron 2, and cell nucleus area followed a similar pattern. [3H]-thymidine autoradiography demonstrated that neurons were added continuously throughout the nucleus during embryonic and larval development

  20. Activation of the retrotrapezoid nucleus by posterior hypothalamic stimulation

    Science.gov (United States)

    Fortuna, Michal G; Stornetta, Ruth L; West, Gavin H; Guyenet, Patrice G

    2009-01-01

    The retrotrapezoid nucleus (RTN) contains chemically defined neurons (ccRTN neurons) that provide a pH-regulated excitatory drive to the central respiratory pattern generator. Here we test whether ccRTN neurons respond to stimulation of the perifornical hypothalamus (PeF), a region that regulates breathing during sleep, stress and exercise. PeF stimulation with gabazine increased blood pressure, phrenic nerve discharge (PND) and the firing rate of ccRTN neurons in isoflurane-anaesthetized rats. Gabazine produced an approximately parallel upward shift of the steady-state relationship between ccRTN neuron firing rate and end-tidal CO2, and a similar shift of the relationship between PND and end-tidal CO2. The central respiratory modulation of ccRTN neurons persisted after gabazine without a change in pattern. Morphine administration typically abolished PND and reduced the discharge rate of most ccRTN neurons (by 25% on average). After morphine administration, PeF stimulation activated the ccRTN neurons normally but PND activation and the central respiratory modulation of the ccRTN neurons were severely attenuated. In the same rat preparation, most (58%) ccRTN neurons expressed c-Fos after exposure to hypercapnic hyperoxia (6–7% end-tidal CO2; 3.5 h; no hypothalamic stimulation) and 62% expressed c-Fos under hypocapnia (∼3% end-tidal CO2) after PeF stimulation. Under baseline conditions (∼3% end-tidal CO2, hyperoxia, no PeF stimulation) few (11%) ccRTN neurons expressed c-Fos. In summary, most ccRTN neurons are excited by posterior hypothalamic stimulation while retaining their normal response to CNS acidification. ccRTN neurons probably contribute both to the chemical drive of breathing and to the feed-forward control of breathing associated with emotions and or locomotion. PMID:19752119

  1. J/ψ production in proton-nucleus and nucleus-nucleus interactions at the CERN SPS

    International Nuclear Information System (INIS)

    The NA38 and NA50 experiments at the CERN SPS have measured charmonium production in different colliding systems with the aim of observing a phase transition from ordinary hadronic matter towards a state in which quarks and gluons are deconfined (Quark Gluon Plasma, QGP). This experimental research is based on the prediction that the J/ψ yield should be suppressed in deconfined matter. The analysis of the data collected by the NA50 experiment with Pb-Pb collisions at 158 GeV/c per nucleon shows that the J/ψ is anomalously suppressed with respect to the pattern observed in proton-nucleus and light ion reactions. (orig.)

  2. Jet Tomography of High-Energy Nucleus-Nucleus Collisions at Next-to-Leading Order

    International Nuclear Information System (INIS)

    We demonstrate that jet observables are highly sensitive to the characteristics of the vacuum and the in-medium QCD parton showers and propose techniques that exploit this sensitivity to constrain the mechanism of quark and gluon energy loss in strongly interacting plasmas. As a first example, we calculate the inclusive jet cross section in high-energy nucleus-nucleus collisions to O(αs3). Theoretical predictions for the medium-induced jet broadening and the suppression of the jet production rate due to cold and hot nuclear matter effects in Au+Au and Cu+Cu reactions at RHIC are presented.

  3. Aspects of Coulomb dissociation and interference in peripheral nucleus-nucleus collisions

    Energy Technology Data Exchange (ETDEWEB)

    Nystrand, Joakim; Baltz, Anthony; Klein, Spencer R.

    2001-10-21

    Coherent vector meson production in peripheral nucleus-nucleus collisions is discussed. These interactions may occur for impact parameters much larger than the sum of the nuclear radii. Since the vector meson production is always localized to one of the nuclei, the system acts as a two-source interferometer in the transverse plane. By tagging the outgoing nuclei for Coulomb dissociation it is possible to obtain a measure of the impact parameter and thus the source separation in the interferometer. This is of particular interest since the life-time of the vector mesons are generally much shorter than the impact parameters of the collisions.

  4. Development of silicon pixels for strangeness detection in nucleus-nucleus collisions

    Energy Technology Data Exchange (ETDEWEB)

    Antinori, F. [CERN, European Organization for Nuclear Research, CH-1211 Geneva 23 (Switzerland)]|[Dipartimento di Fisica dell`Universita and Sezione INFN, I-16146 Genoa (Italy); Barberis, D. [Dipartimento di Fisica dell`Universita and Sezione INFN, I-16146 Genoa (Italy); Beker, H. [Dipartimento di Fisica dell`Universita ``La Sapienza`` and Sezione INFN, I-00185 Rome (Italy); Beusch, W.; Campbell, M.; Cantatore, E. [CERN, European Organization for Nuclear Research, CH-1211 Geneva 23 (Switzerland); Catanesi, M.G. [Dipartimento di Fisica dell`Universita and Sezione INFN, I-70124 Bari (Italy); Chesi, E. [CERN, European Organization for Nuclear Research, CH-1211 Genova 23 (Switzerland); Darbo, G. [Dipartimento di Fisica dell`Universita and Sezione INFN, I-70124 Bari (Italy); Di Bari, D. [Dipartimento di Fisica dell`Universita and Sezione INFN, I-70124 Bari (Italy); Di Liberto, S. [Dipartimento di Fisica dell`Universita ``La Sapienza`` and Sezione INFN, I-00185 Rome (Italy); Elia, D. [Dipartimento di Fisica dell-Universita and Sezione INFN, I-70124 Bari (Italy); Heijne, E.H.M.; Helstrup, H.; Jacholkowski, A.; Klempt, W.; Knudson, K. [CERN, European Organization for Nuclear Research, CH-1211 Geneva 23 (Switzerland); Kralik, I. [Institute of Experimental Physics, SK-04353 Kosice (Slovakia); Lassalle, J.C. [CERN, European Organization for Nuclear Research, CH-1211 Geneva 23 (Switzerland); Lenti, V. [Dipartimento di Fisica dell`Universita and Sezione INFN, I-70124 Bari (Italy); Lopez, L. [CERN, European Organization for Nuclear Research, CH-1211 Geneva 23 (Switzerland); Luptak, M. [Institute of Experimental Physics, SK-04353 Kosice (Slovakia); Martinengo, P. [CERN, European Organization for Nuclear Research, CH-1211 Geneva 23 (Switzerland); Meddi, F. [Dipartimento di Fisica dell`Universita ``La Sapienza`` and Sezione INFN, I-00185 Rome (Italy); Middelkamp, P. [CERN, European Organization for Nuclear Research, CH-1211 Geneva 23 (Switzerland); Presented by...

    1995-07-20

    Silicon microdetectors and in particular the novel silicon pixel detectors open up the way for a comprehensive study of strangeness detection in nucleus-nucleus collisions. We outline the philosophy behind this approach, describe an application in the pixel-based heavy-ion experiment WA97, and give some preliminary results on the performance of four silicon pixels planes in the 1994 Pb beam run of WA97. We conclude with an outlook on some possible future applications of silicon pixels. {copyright} 1995 {ital American} {ital Institute} {ital of} {ital Physics}.

  5. Development of silicon pixels for strangeness detection in nucleus-nucleus collisions

    International Nuclear Information System (INIS)

    Silicon microdetectors and in particular the novel silicon pixel detectors open up the way for a comprehensive study of strangeness detection in nucleus-nucleus collisions. We outline the philosophy behind this approach, describe an application in the pixel-based heavy-ion experiment WA97, and give some preliminary results on the performance of four silicon pixels planes in the 1994 Pb beam run of WA97. We conclude with an outlook on some possible future applications of silicon pixels. copyright 1995 American Institute of Physics

  6. Dynamical aspects of intermediate-energy nucleus-nucleus collisions. Pt. 4

    International Nuclear Information System (INIS)

    The production of pions in intermediate energy nucleus-nucleus collisions by incoherent nucleon-nucleon collisions is studied within a microscopic quantal phase-space approach. Employing free production rates for the elementary process N+N → π+X experimental data for inclusive pion yields are approximately reproduced from 20-150 MeV/u within the first collision approximation. These results indicate that cooperative phenomena - apart from the time-dependent mean field - seem to play a minor role for energetic particle production even at very low bombarding energy. (orig.)

  7. Pion and Kaon Lab Frame Differential Cross Sections for Intermediate Energy Nucleus-Nucleus Collisions

    Science.gov (United States)

    Norbury, John W.; Blattnig, Steve R.

    2008-01-01

    Space radiation transport codes require accurate models for hadron production in intermediate energy nucleus-nucleus collisions. Codes require cross sections to be written in terms of lab frame variables and it is important to be able to verify models against experimental data in the lab frame. Several models are compared to lab frame data. It is found that models based on algebraic parameterizations are unable to describe intermediate energy differential cross section data. However, simple thermal model parameterizations, when appropriately transformed from the center of momentum to the lab frame, are able to account for the data.

  8. The effect of the relative nuclear size on the nucleus-nucleus interactions

    Science.gov (United States)

    Erofeeva, I. N.; Murzin, V. S.; Sivoklokov, S. Y.; Smirnova, L. N.

    1985-01-01

    The experimental data on the interactions of light nuclei (d, He(4), C(12)) at the momentum 4.2 GeV/cA with the carbon nuclei were taken in the 2-m propane bubble chamber. The distributions in the number of interacting nucleons, the spectra of protons, the mean energies of secondary pions and protons, the mean fractions of energy transferred to the pion and nucleon components are presented. The results of the investigation of the mechanism of nucleus-nucleus interactions can be used to calculate the nuclear cascades in the atmosphere.

  9. The cell nucleus taking centre stage. Workshop on the functional organization of the cell nucleus

    Czech Academy of Sciences Publication Activity Database

    Gruenbaum, Y.; Raška, Ivan; Herrmann, H.

    2006-01-01

    Roč. 7, č. 12 (2006), s. 1211-1215. ISSN 1469-221X. [EMBO Workshop on the Functional Organization of the Cell Nucleus /3./. Prague, 05.05.2006-08.05.2006] R&D Projects: GA ČR(CZ) GA304/04/0692; GA ČR(CZ) GA304/06/1691; GA MŠk(CZ) LC535 Institutional research plan: CEZ:AV0Z50110509 Keywords : cell nucleus * nuclear dynamics * nuclear structure and disease Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 8.175, year: 2006

  10. Azimuthal correlations of hadrons and fragments in nucleus-nucleus collisions

    Institute of Scientific and Technical Information of China (English)

    LI Hui-Ling

    2011-01-01

    Two-particle (two-fragment) azimuthal correlation functions are studied by using a simple formula which describes uniformly azimuthal distributions of final-state charged particles and nuclear fragments.This formula is obtained in the framework of a multi-source thermal model (or multi-source ideal gas model).The calculated results are compared and found to be in agreement with the experimental data of charged hadrons and nuclear fragments in nucleus-nucleus collisions at intermediate and high energies.

  11. Nucleus-nucleus potential, energy dissipation and mass dispersion in fusion and transfer reactions

    CERN Document Server

    Washiyama, Kouhei; Ayik, Sakir

    2009-01-01

    The nucleus-nucleus potential and energy dissipation in fusion reactions are obtained from microscopic mean-field dynamics. The deduced potentials nicely reproduce the one extracted from experimental data. Energy dissipation shows a universal behaviour between different reactions. Also, the dispersion of mass distribution in transfer reaction is investigated in a stochastic mean-field dynamics. By including initial fluctuations in collective space, the description of the dispersion is much improved compared to that of mean field only. The result is consistent with the macroscopic phenomenological analysis of the experimental data.

  12. Nuclear structure and neutrino-nucleus interaction

    International Nuclear Information System (INIS)

    Recent years have witnessed an intense experimental and theoretical activity oriented towards a better comprehension of neutrino nucleus interaction. While the main motivation for this task is the demand coming from oscillation experiments in their search for a precise determination of neutrino properties, the relevance of neutrino interaction with matter is more wide-ranging. It is imperative for astrophysics, hadronic and nuclear physics, and physics beyond the standard model. The experimental information on neutrino induced reactions is rapidly growing, and the corresponding theoretical description is a challenging proposition, since the energy scales of interest span a vast region, going from few MeV for solar neutrinos, to tens of MeV for the interpretation of experiments with the muon and pion decay at rest and the detection of neutrinos coming from the core collapse of supernova, and to hundreds of MeV or few GeV for the detection of atmospheric neutrinos, and for the neutrino oscillation program of the MiniBooNE experiment. The presence of neutrinos, being chargeless particles, can only be inferred by detecting the secondary particles created in colliding and interacting with the matter. Nuclei are often used as neutrino detectors, and in particular 12C which is a component of many scintillator detectors. Thus, the interpretation of neutrino data heavily relies on detailed and quantitative knowledge of the features of the neutrino-nucleus interaction. The nuclear structure methods used in the evaluation of the neutrino-nucleus cross section are reviewed. Detailed comparison between the experimental and theoretical results establishes benchmarks needed for verification and/or parameter adjustment of the nuclear models. Having a reliable tool for such calculation is of great importance in a variety of applications, such as the description of the r-process nucleosynthesis. (author)

  13. From the nucleus discovery to DWBA

    International Nuclear Information System (INIS)

    The author presents a brief review of the main events in the field of nuclear reactions that are acknowledged as milestones because of their importance due to either experimental setting or physical interpretation. It is shown that the pace of discoveries has been strongly dependent on the technical progress in detection means at the beginning of nuclear physics and now is linked to the development of simulation means. The discovery of the neutron, the development of the Geiger counter, the theory of the compound nucleus or the first direct reactions are among these milestones

  14. Contemporary models of the atomic nucleus

    CERN Document Server

    Nemirovskii, P E

    2013-01-01

    Contemporary Models of the Atomic Nucleus discusses nuclear structure and properties, expounding contemporary theoretical concepts of the low-energy nuclear processes underlying in nuclear models. This book focuses on subjects such as the optical nuclear model, unified or collective model, and deuteron stripping reaction. Other topics discussed include the basic nuclear properties; shell model; theoretical analysis of the shell model; and radiative transitions and alpha-decay. The deuteron theory and the liquid drop nuclear model with its application to fission theory are also mentioned, but o

  15. A thalamic input to the nucleus accumbens mediates opiate dependence.

    Science.gov (United States)

    Zhu, Yingjie; Wienecke, Carl F R; Nachtrab, Gregory; Chen, Xiaoke

    2016-02-11

    Chronic opiate use induces opiate dependence, which is characterized by extremely unpleasant physical and emotional feelings after drug use is terminated. Both the rewarding effects of a drug and the desire to avoid withdrawal symptoms motivate continued drug use, and the nucleus accumbens is important for orchestrating both processes. While multiple inputs to the nucleus accumbens regulate reward, little is known about the nucleus accumbens circuitry underlying withdrawal. Here we identify the paraventricular nucleus of the thalamus as a prominent input to the nucleus accumbens mediating the expression of opiate-withdrawal-induced physical signs and aversive memory. Activity in the paraventricular nucleus of the thalamus to nucleus accumbens pathway is necessary and sufficient to mediate behavioural aversion. Selectively silencing this pathway abolishes aversive symptoms in two different mouse models of opiate withdrawal. Chronic morphine exposure selectively potentiates excitatory transmission between the paraventricular nucleus of the thalamus and D2-receptor-expressing medium spiny neurons via synaptic insertion of GluA2-lacking AMPA receptors. Notably, in vivo optogenetic depotentiation restores normal transmission at these synapses and robustly suppresses morphine withdrawal symptoms. This links morphine-evoked pathway- and cell-type-specific plasticity in the paraventricular nucleus of the thalamus to nucleus accumbens circuit to opiate dependence, and suggests that reprogramming this circuit holds promise for treating opiate addiction. PMID:26840481

  16. μ-ICC2.45在线微波浓度测量仪服务于沼气加工和污水污泥的处理%The Application of μ-ICC 2.45 On-line Microwave Concentration Measurement in the Processing of Biogas and Sewage Sludge

    Institute of Scientific and Technical Information of China (English)

    赵剑峰; K.-H.Theisen; M.Deutsch

    2012-01-01

    This article describes that the process of biogas and treatment of sewage,sludge was detected by the instrument of proMtec on-line microware concentration measurement.With its novel measurement means and unique structural design,the instrument was used to measure the on-line TS-content of materials which entering and discharging from the fermentation tank,this method could achieve the suitable material balance and maximal methane profits.The method also plays an important monitoring role in the whole process and would save energy and reduce emission.For comparison with the conventional measurement,μ-ICC 2.45 measuring system has more advantages,which will not be affected on the coating and storage,and the transmitter can be installed directly on the large pipeline or tank.%本文介绍proMtec在线实时微波浓度测量仪在沼气生产中对填料的浓度、污水污泥处理过程中对污泥浓度密度进行测量的应用。以其新颖的测量手段和独特的结构设计,对进入发酵罐物料和其卸料的在线TS-含量进行监控,以达到最理想的物料平衡,提高细菌的活性,使沼气收益最大化。在线式实时监控,有利于对生产过程的即时掌控,帮助实现节能减排。相比较传统测量方法,μ-ICC 2.45测量设备探头不受结垢、堵塞的影响,可直接安装于大口径的管路或是箱体上。

  17. Prestress mediates force propagation into the nucleus

    International Nuclear Information System (INIS)

    Several reports show that the nucleus is 10 times stiffer than the cytoplasm. Hence, it is not clear if intra-nuclear structures can be directly deformed by a load of physiologic magnitudes. If a physiologic load could not directly deform intra-nuclear structures, then signaling inside the nucleus would occur only via the mechanisms of diffusion or translocation. Using a synchronous detection approach, we quantified displacements of nucleolar structures in cultured airway smooth muscle cells in response to a localized physiologic load (∼0.4 μm surface deformation) via integrin receptors. The nucleolus exhibited significant displacements. Nucleolar structures also exhibited significant deformation, with the dominant strain being the bulk strain. Increasing the pre-existing tensile stress (prestress) in the cytoskeleton significantly increased the stress propagation efficiency to the nucleolus (defined as nucleolus displacement per surface deformation) whereas decreasing the prestress significantly lowered the stress propagation efficiency to the nucleolus. Abolishing the stress fibers/actin bundles by plating the cells on poly-L-lysine-coated dishes dramatically inhibited stress propagation to the nucleolus. These results demonstrate that the prestress in the cytoskeleton is crucial in mediating stress propagation to the nucleolus, with implications for direct mechanical regulation of nuclear activities and functions

  18. Radiative corrections to pion-nucleus bremsstrahlung

    CERN Document Server

    Kaiser, N

    2008-01-01

    We calculate the one-photon loop radiative corrections to virtual pion Compton scattering $\\pi^- \\gamma^* \\to \\pi^- \\gamma$, that subprocess which determines in the one-photon exchange approximation the pion-nucleus bremsstrahlung reaction $\\pi^- Z\\to \\pi^- Z \\gamma$. Ultraviolet and infrared divergencies of the loop integrals are both treated by dimensional regularization. Analytical expressions for the ${\\cal O}(\\alpha)$ corrections to the virtual Compton scattering amplitudes, $A(s,u,Q)$ and $B(s,u,Q)$, are derived with their full dependence on the (small) photon virtuality $Q$ from 9 classes of contributing one-loop diagrams. Infrared finiteness of these virtual radiative corrections is achieved (in the standard way) by including soft photon radiation below an energy cut-off $\\lambda$. In the region of low $\\pi^- \\gamma$ center-of-mass energies, where the pion-nucleus bremsstrahlung process is used to extract the pion electric and magnetic polarizabilities, we find radiative corrections up to about -3% fo...

  19. Electromagnetic transitions in the 16O nucleus

    International Nuclear Information System (INIS)

    The knowledge of mean lives, and therefore of total widths of nuclei excited states, is critical as it allows the absolute value of nuclear matrix elements to be attained, and thus information on wave functions of the involved level and of the levels reached by de-excitation of this last one. However, the total width of a level can be decomposed into a sum of partial widths which can be independently obtained by absolute efficiency measurements or by branching fraction measurements when the mean life of the studied level is known. The objective of this research thesis is therefore to determine some partial widths in the Oxygen 16 nucleus. Mean lives of the first excited levels have been experimentally measured and some electromagnetic transitions have been studied. The author comments models which are proposed for the oxygen 16 nucleus, describes the experimental techniques and the experiments mainly performed on the Strasbourg Van de Graaff accelerator, and compares the obtained results with values deduced from theoretical works

  20. NUCLEUS-CHART. Chart of the Nuclides

    Energy Technology Data Exchange (ETDEWEB)

    Atomic Mass Data Center [Orsy (France)

    1998-05-05

    Nucleus is an interactive PC-based graphical viewer of NUBASE nuclear property data. NUBASE contains experimentally known nuclear properties, together with some values that have been estimated from extrapolation of experimental data for 3010 nuclides. NUBASE also contains data on those isomeric states that have half-lives greater than 1 millisecond; there are 669 such nuclides of which 58 have more than one isomeric state. The latest version of NUCLEUS-CHART has been corrected to include the names and the chemical symbols of the elements 104 to 109 that have been finally adopted by the Commission on Nomenclature of Inorganic Chemistry (CNIC) of the International Union of Pure and Applied Chemistry (IUPAC). They differ from those recommended by the same commission a few years before and that were widely used in the evaluations AME`95 and NUBASE`97. It results in some shuffling of the names and symbols, that may cause confusion in the near future. At AMDC we`ll be as careful as possible to try to avoid such confusion. In advance we apologize if any will occur in the future and recommend the user to always double check these few names.

  1. Energy levels in (7Li) nucleus

    International Nuclear Information System (INIS)

    The energies of the normal-parity states and positive parity states in (7Li) nucleus are calculated, using many-particle nuclear shell-model, and the harmonic oscillator-wave-functions, over the residual interaction of the Gaussian from the Serber force. Spin-orbit interactions are neglected. The kinetic energy is introduced as a variant quantity, through the variation of the harmonic oscillator parameter (r0) (r02=h/mw). Finally, we separate the ''spurious'' states (one quantum excitations of the center of mass of the nucleus) by the effect of the operator (R-i), for the coordinate of the center of mass on the different wave-functions of the ground state-configurations. The calculations show that the energy of the positive-parity states, separated into two groups; the first in the energy region (10-20 Mev) and described by the symmetries (43), (421); and the second group in the energy region (26-46 Mev) and described by the symmetries (31), (3211). 9 tabs.; 3 figs.; 64 refs

  2. Highly-anisotropic hydrodynamics for central collisions

    CERN Document Server

    Ryblewski, Radoslaw

    2016-01-01

    The framework of leading-order anisotropic hydrodynamics is supplemented with realistic equation of state and self-consistent freeze-out prescription. The model is applied to central proton-nucleus collisions. The results are compared to those obtained within standard Israel-Stewart second-order viscous hydrodynamics. It is shown that the resulting hadron spectra are highly-sensitive to the hydrodynamic approach that has been used.

  3. A search for {phi} meson nucleus bound state using antiproton annihilation on nucleus

    Energy Technology Data Exchange (ETDEWEB)

    Ohnishi, H., E-mail: h-ohnishi@riken.jp [RIKEN, RIKEN Nishina Center (Japan); Buehler, P.; Cargnelli, M. [Stefan-Meyer-Institut fNur subatomare Physik (Austria); Curceanu, C.; Guaraldo, C. [Laboratori Nazionali di Frascati dellf INFN (Italy); Hartmann, O. [Stefan-Meyer-Institut fNur subatomare Physik (Austria); Hicks, K. [Ohio University, Department of Physics and Astronomy (United States); Iwasaki, M. [RIKEN, RIKEN Nishina Center (Japan); Ishiwatari, T. [Stefan-Meyer-Institut fNur subatomare Physik (Austria); Kienle, P. [Technische Universiat Munchen (Germany); Marton, J. [Stefan-Meyer-Institut fuer subatomare Physik (Austria); Muto, R.; Naruki, M. [KEK (High Energy Accelerator Research Organization) (Japan); Niiyama, M. [Kyoto University, Department of Physics (Japan); Noumi, H. [Osaka University, Research Center for Nuclear Physics (Japan); Okada, S.; Vidal, A. Romero [Laboratori Nazionali di Frascati dellf INFN (Italy); Sakaguchi, A. [Osaka University, Department of Physics (Japan); Sakuma, F. [RIKEN, RIKEN Nishina Center (Japan); Sawada, S. [KEK (High Energy Accelerator Research Organization) (Japan); and others

    2012-12-15

    The mass shift of the vector mesons in nuclei is known to be a powerful tool for investigating the mechanism of generating hadron mass from the QCD vacuum. The mechanism is known to be the spontaneous breaking of chiral symmetry. In 2007, KEK-PS E325 experiment reported about 3.4 % mass reduction of the {phi} meson in medium-heavy nuclei (Cu). This result is possibly one of the indications of the partial restoration of chiral symmetry in nuclei, however, unfortunately it is hard to make strong conclusions from the data. One of the ways to conclude the strength of the {phi} meson mass shift in nuclei will be by trying to produce only slowly moving {phi} mesons where the maximum nuclear matter effect can be probed. The observed mass reduction of the {phi} meson in the nucleus can be translated as the existence of an attractive force between {phi} meson and nucleus. Thus, one of the extreme conditions that can be achieved in the laboratory is indeed the formation of a {phi}-nucleus bound state, where the {phi} meson is 'trapped' in the nucleus. The purpose of the experiment is to search for a {phi}-nucleus bound state and measure the binding energy of the system. We will demonstrate that a completely background-free missing-mass spectrum can be obtained efficiently by (p-bar, {phi}) spectroscopy together with K{sup + }{Lambda} tagging, using the primary reaction channel p-bar p {yields} {phi} {phi}. This paper gives an overview of the physics motivation and the detector concept, and explains the direction of the initial research and development effort.

  4. A search for ϕ meson nucleus bound state using antiproton annihilation on nucleus

    Science.gov (United States)

    Ohnishi, H.; Bühler, P.; Cargnelli, M.; Curceanu, C.; Guaraldo, C.; Hartmann, O.; Hicks, K.; Iwasaki, M.; Ishiwatari, T.; Kienle, P.; Marton, J.; Muto, R.; Naruki, M.; Niiyama, M.; Noumi, H.; Okada, S.; Vidal, A. Romero; Sakaguchi, A.; Sakuma, F.; Sawada, S.; Sirghi, D.; Sirghi, F.; Suzuki, K.; Tsukada, K.; Doce, O. Vazquez; Widmann, E.; Yokkaichi, S.; Zmeskal, J.

    The mass shift of the vector mesons in nuclei is known to be a powerful tool for investigating the mechanism of generating hadron mass from the QCD vacuum. The mechanism is known to be the spontaneous breaking of chiral symmetry. In 2007, KEK-PS E325 experiment reported about 3.4 % mass reduction of the ϕ meson in medium-heavy nuclei (Cu). This result is possibly one of the indications of the partial restoration of chiral symmetry in nuclei, however, unfortunately it is hard to make strong conclusions from the data. One of the ways to conclude the strength of the ϕ meson mass shift in nuclei will be by trying to produce only slowly moving ϕ mesons where the maximum nuclear matter effect can be probed. The observed mass reduction of the ϕ meson in the nucleus can be translated as the existence of an attractive force between ϕ meson and nucleus. Thus, one of the extreme conditions that can be achieved in the laboratory is indeed the formation of a ϕ-nucleus bound state, where the ϕ meson is "trapped" in the nucleus. The purpose of the experiment is to search for a ϕ-nucleus bound state and measure the binding energy of the system. We will demonstrate that a completely background-free missing-mass spectrum can be obtained efficiently by (bar{p}, φ) spectroscopy together with K + Λ tagging, using the primary reaction channel bar{p} p rightarrow φ φ. This paper gives an overview of the physics motivation and the detector concept, and explains the direction of the initial research and development effort.

  5. Physical role for the nucleus in cell migration

    Science.gov (United States)

    Fruleux, Antoine; Hawkins, Rhoda J.

    2016-09-01

    Cell migration is important for the function of many eukaryotic cells. Recently the nucleus has been shown to play an important role in cell motility. After giving an overview of cell motility mechanisms we review what is currently known about the mechanical properties of the nucleus and the connections between it and the cytoskeleton. We also discuss connections to the extracellular matrix and mechanotransduction. We identify key physical roles of the nucleus in cell migration.

  6. Physical role for the nucleus in cell migration.

    Science.gov (United States)

    Fruleux, Antoine; Hawkins, Rhoda J

    2016-09-14

    Cell migration is important for the function of many eukaryotic cells. Recently the nucleus has been shown to play an important role in cell motility. After giving an overview of cell motility mechanisms we review what is currently known about the mechanical properties of the nucleus and the connections between it and the cytoskeleton. We also discuss connections to the extracellular matrix and mechanotransduction. We identify key physical roles of the nucleus in cell migration. PMID:27406341

  7. Nucleus management in manual small incision cataract surgery by phacosection

    OpenAIRE

    Ravindra M

    2009-01-01

    Nucleus management is critical in manual small incision cataract surgery (MSICS), as the integrity of the tunnel, endothelium and posterior capsule needs to be respected. Several techniques of nucleus management are in vogue, depending upon the specific technique of MSICS. Nucleus can be removed in toto or bisected or trisected into smaller segments. The pressure in the eye can be maintained at the desired level with the use of an anterior chamber maintainer or kept at atmospheric levels. In ...

  8. The planetary nebula Abell 48 and its [WN4] nucleus

    CERN Document Server

    Frew, David J; Parker, Q A; Stupar, M; Wachter, S; DePew, K; Danehkar, A; Fitzgerald, M F

    2013-01-01

    We have conducted a detailed multi-wavelength study of the peculiar planetary nebula Abell 48 and its central star. We present evidence for a new classification of the nucleus as a helium-rich, hydrogen-deficient star of type [WN4], one of only two currently known examples of its type. The evidence for either a massive WN or a low-mass [WN] interpretation is critically examined, and we firmly conclude that Abell 48 is a planetary nebula around an evolved low-mass star, rather than a Population I ejecta nebula. Importantly, the surrounding nebula has a morphology typical of planetary nebulae, and is not enriched in nitrogen, and thus not the 'peeled atmosphere' of a massive star. We estimate a distance of 1.6 kpc and a reddening, E(B-V) = 1.90 mag, the latter value clearly showing the nebula lies on the near side of the Galactic bar, and therefore cannot be a massive WN star. The planetary nebula has an ionized mass (0.3 M_sun) and electron density (740 cm^-3) typical of somewhat evolved objects. The observed ...

  9. Comparative study of alpha + nucleus elastic scattering using different models

    International Nuclear Information System (INIS)

    The alpha (α) elastic scattering from different targets potential over the energy range 10–240 MeV has been analyzed in the framework of the single-folding (SF) optical model. Four targets are considered, namely, 24Mg, 28Si, 32S and 40Ca. The SF calculations for the real central part of the nuclear optical potential are performed by folding an effective α–α interaction with the α-cluster distribution density in the target nucleus. The imaginary part of the optical potential is expressed in the phenomenological Woods–Saxon (WS) form. The calculated angular distributions of the elastic scattering differential cross-section using the derived semimicroscopic potentials successfully reproduce 36 sets of data all over the measured angular ranges. The obtained results confirm the validity of the α-cluster structure of the considered nuclei. For the sake of comparison, the same sets of data are reanalyzed using microscopic double-folded optical potentials based upon the density-dependent Jeukenne–Lejeune–Mahaux (JLM) effective nucleon–nucleon interaction. (author)

  10. Anterior nucleus of the thalamus: functional organization and clinical implications.

    Science.gov (United States)

    Child, Nicholas D; Benarroch, Eduardo E

    2013-11-19

    The anterior nucleus of thalamus (ANT) is a key component of the hippocampal system for episodic memory. The ANT consist of 3 subnuclei with distinct connectivity with the subicular cortex, retrosplenial cortex, and mammillary bodies. Via its connections with the anterior cingulate and orbitomedial prefrontal cortex, the ANT may also contribute to reciprocal hippocampal-prefrontal interactions involved in emotional and executive functions. As in other thalamic nuclei, neurons of the ANT have 2 different state-dependent patterns of discharge, tonic and burst-firing; some ANT neurons also contribute to propagation of the theta rhythm, which is important for mechanisms of synaptic plasticity of the hippocampal circuit. Clinical and experimental evidence indicate that damage of the ANT or its inputs from the mammillary bodies are primarily responsible for the episodic memory deficit observed in Wernicke-Korsakoff syndrome and thalamic stroke. Experimental models also indicate that the ANT may have a role in the propagation of seizure activity both in absence and in focal seizures. Because of its central connectivity and possible role in propagation of seizure activity, the ANT has become an attractive target for deep brain stimulation (DBS) for treatment of medically refractory epilepsy. The ANT is one of the nuclei preferentially affected in prion disorders, such as fatal familial insomnia, but the relationship between ANT involvement and the clinical manifestations of these disorders remains unclear. The connectivity patterns and electrophysiology of the ANT have been the subject of several reviews.(1-4.) PMID:24142476

  11. Diverse Perspectives for Global Impact: Summary of ICCE2012%技术影响全球教育的多维视角——第20届计算机教育国际会议(ICCE 2012)综述

    Institute of Scientific and Technical Information of China (English)

    国莹; 王占芳

    2013-01-01

    2012年11月26日至11月30日在新加坡举行了“第20届计算机教育国际会议(ICCE2012)”.来自29个国家的360多位专家、学者、教育工作者和博士生参加了本次会议,以“全球影响的多维视角”为主题,对计算机教育领域的新近研究成果进行探讨和交流.通过对会议主题报告、游戏化学习、智能化学习、移动学习、个性化学习、协作学习、语言学习和发展中国家ICT的发展趋势的重要议题进行综述,探讨计算机教育领域研究与实践发展趋势.

  12. Hyperdeformed band in the 36Ar nucleus?

    International Nuclear Information System (INIS)

    Complete text of publication follows. The exotic shapes of atomic nuclei has attracted much attention recently both from the experimental and from the theoretical sides. E.g. the superdeformed (SD) shape in N = Z nuclei were observed experimentally during the last decade. In particular the SD band of the 36Ar nucleus was detected in 2000 [1]. Following the experimental observation a considerable theoretical effort has been concentrated on this band. In [2] e.g. the possible binary clusterizations of this state was studied systematically. Similar studies have been done also for the ground, and the hyperdeformed band. The latter one had been predicted from alphacluster model calculations [3]. The possible binary cluster-configurations are important not only for the better understanding of the structure of the shape isomers, but also from the viewpoint of predicting the favoured reaction channels to populate these states. This is the straightforward consequence of the close relation between the clusterization and reaction channels. (In fact, a cluster-configuration is defined by the reaction channel in which it can be observed.) One of the interesting conclusions of the work [2] was, that the hyperdeformed (HD) state of the 36Ar nucleus could be populated in the 24Mg+12C and 20Ne+16O reactions. A recent analysis of the 24Mg+12C elastic scattering [4] revealed the fact that the cross section can be described only by supposing resonances on top of the potential scattering. This very careful analysis incorporated phase-shift study, as well as Regge-pole and energy-dependent resonance calculations. The existence of five resonances have been proved, which have angular momenta 2, 4, 6, 7, 8. These states together with the resonances from the 20Ne+16O reactions seem to establish a rotational band, as shown in the upper part of Fig. 1. Its moment of inertia is in a very good agreement with that of the HD shape predicted from alpha-cluster model [3]. The similarity of the

  13. Thermal Bremsstrahlung probing nuclear multifragmentation in nucleus-nucleus collisions around the Fermi energy; Bremsstrahlung thermique comme sonde de la multifragmentation nucleaire dans les collisions noyau-noyau aux energies de Fermi

    Energy Technology Data Exchange (ETDEWEB)

    D' Enterria, D.G

    2000-05-15

    The thermodynamical properties of nuclear matter at moderate temperatures and densities, in the vicinity of the predicted nuclear liquid-gas phase transition, are studied using as experimental probe the hard-photons (E{sub {gamma}} > 30 MeV) emitted in nucleus-nucleus collisions. Photon and charged-particle production in four different heavy-ion reactions (Ar{sup 36} + Au{sup 197}, Ag{sup 107}, Ni{sup 58}, C{sup 12} at 60 A*MeV) is measured exclusively and inclusively coupling the TAPS photon spectrometer with two charged-particle and intermediate-mass-fragment detectors covering nearly 4{pi}. We confirm that Bremsstrahlung emission in first-chance (off-equilibrium) proton-neutron collisions (pn{gamma}) is the dominant origin of hard photons. We also firmly establish the existence of a thermal radiation component emitted in second-chance proton-neutron collisions. This thermal Bremsstrahlung emission takes place in semi-central and central nucleus-nucleus reactions involving heavy targets. We exploit this observation i) to demonstrate that thermal equilibrium is reached during the reaction, ii) to establish a new thermometer of nuclear matter based on Bremsstrahlung photons, iii) to derive the thermodynamical properties of the excited nuclear sources and, in particular, to establish a 'caloric curve' (temperature versus excitation energy), and iv) to assess the time-scales of the nuclear break-up process. (author)

  14. Membrane-To-Nucleus Signaling Links Insulin-Like Growth Factor-1- and Stem Cell Factor-Activated Pathways

    Science.gov (United States)

    Hayashi, Yujiro; Asuzu, David T.; Gibbons, Simon J.; Aarsvold, Kirsten H.; Bardsley, Michael R.; Lomberk, Gwen A.; Mathison, Angela J.; Kendrick, Michael L.; Shen, K. Robert; Taguchi, Takahiro; Gupta, Anu; Rubin, Brian P.; Fletcher, Jonathan A.; Farrugia, Gianrico; Urrutia, Raul A.; Ordog, Tamas

    2013-01-01

    Stem cell factor (mouse: Kitl, human: KITLG) and insulin-like growth factor-1 (IGF1), acting via KIT and IGF1 receptor (IGF1R), respectively, are critical for the development and integrity of several tissues. Autocrine/paracrine KITLG-KIT and IGF1-IGF1R signaling are also activated in several cancers including gastrointestinal stromal tumors (GIST), the most common sarcoma. In murine gastric muscles, IGF1 promotes Kitl-dependent development of interstitial cells of Cajal (ICC), the non-neoplastic counterpart of GIST, suggesting cooperation between these pathways. Here, we report a novel mechanism linking IGF1-IGF1R and KITLG-KIT signaling in both normal and neoplastic cells. In murine gastric muscles, the microenvironment for ICC and GIST, human hepatic stellate cells (LX-2), a model for cancer niches, and GIST cells, IGF1 stimulated Kitl/KITLG protein and mRNA expression and promoter activity by activating several signaling pathways including AKT-mediated glycogen synthase kinase-3β inhibition (GSK3i). GSK3i alone also stimulated Kitl/KITLG expression without activating mitogenic pathways. Both IGF1 and GSK3i induced chromatin-level changes favoring transcriptional activation at the Kitl promoter including increased histone H3/H4 acetylation and H3 lysine (K) 4 methylation, reduced H3K9 and H3K27 methylation and reduced occupancy by the H3K27 methyltransferase EZH2. By pharmacological or RNA interference-mediated inhibition of chromatin modifiers we demonstrated that these changes have the predicted impact on KITLG expression. KITLG knock-down and immunoneutralization inhibited the proliferation of GIST cells expressing wild-type KIT, signifying oncogenic autocrine/paracrine KITLG-KIT signaling. We conclude that membrane-to-nucleus signaling involving GSK3i establishes a previously unrecognized link between the IGF1-IGF1R and KITLG-KIT pathways, which is active in both physiologic and oncogenic contexts and can be exploited for therapeutic purposes. PMID:24116170

  15. 孤束核胆碱能与组胺能系统对颈动脉窦压力感受器反射调节的交互作用%Involvement of cross interaction between central cholinergic and histaminergic systems in the nucleus tractus solitarius in regulating carotid sinus baroreceptor reflex

    Institute of Scientific and Technical Information of China (English)

    胡力旬; 张国兴; 张玉英; 赵红芬; 于康英; 王国卿

    2013-01-01

    脑胆碱能系统与组胺能系统影响颈动脉窦压力感受器反射(carotid sinus baroreceptor reflex,CSR)活动,然而二者是否在孤束核(nucleus tractus solitarius,NTS)水平相互作用,跨转调节CSR,尚不清楚.本文在麻醉Sprague-Dawley (SD)大鼠孤离的一侧颈动脉窦区,通过窦内逐级加压引发CSR和动脉血压变化,经Logistic五参数曲线拟合,求得窦内压(intracarotid sinus pressure,ISP)-平均动脉压(mean arterial pressure,MAP)关系曲线及其特征参数,观察预先在NTS微量注射各选择性胆碱能受体拮抗剂[M1受体拮抗剂哌仑西平(pirenzepine,PRZ)、M2受体拮抗剂美索曲明(methoctramine,MTR)或N1受体拮抗剂六烃季胺(hexamethonium,HEX)]对侧脑室微量注射(intracerebroventricular injection,i.c.v.)组胺(histamine,HA)所致CSR变化的影响,以及预先在NTS微量注射组胺能H1受体拮抗剂氯苯吡胺(chlorpheniramine,CHL)或H2受体拮抗剂西咪替丁(cimetidine,CIM)对i.c.v.拟胆碱药毒扁豆碱(physostigmine,PHY)所致CSR变化的影响,以期解析中枢两大系统对CSR是否具有跨转调节机制.结果显示:(1)单独NTS内注射所给剂量的各选择性胆碱能受体拮抗剂或组胺能受体拮抗剂对CSR均无明显作用(P>0.05),也不引起动脉血压水平明显变动;(2)预先NTS内注射PRZ或MTR可部分翻转i.c.v.HA所致的CSR重调定,表现为ISP-MAP关系曲线在高窦压区明显左下移位(P<0.05),ISP-Gain关系曲线在中窦压区显著上移(P<0.05),反射参数平均动脉压变动范围和最大增益加大(P<0.05),最大增益时的窦内压值与饱和压减少(P<0.05),上述效应中PRZ的作用不如MTR的显著(P<0.05),但HEX对i.c.v.HA所致的CSR变化无明显作用(P>0.05);(3)预先NTS内注射CHL或CIM对i.c.v.PHY所致CSR变化的影响,类似于NTS内注射PRZ或MTR对i.c.v.HA所致CSR变化的作用,且CHL的效应强于CIM (P< 0.05).上述结果表明:侧脑室注射HA所致的CSR重调定机制

  16. Analysis of Intermediate-Energy Nucleus-Nucleus Spallation, Fission, and Fragmentation Reactions with the LAQGSM code

    OpenAIRE

    Mashnik, S. G.; Gudima, K. K.; Prael, R. E.; Sierk, A. J.

    2003-01-01

    The LAQGSM code has been recently developed at Los Alamos National Laboratory to simulate nuclear reactions for proton radiography applications. We have benchmarked our code against most available measured data both for proton-nucleus and nucleus-nucleus interactions at incident energies from 10 MeV to 800 GeV and have compared our results with predictions of other current models used by the nuclear community. Here, we present a brief description of our code and show illustrative results obta...

  17. Delta-nucleus dynamics: proceedings of symposium

    Energy Technology Data Exchange (ETDEWEB)

    Lee, T.S.H.; Geesaman, D.F.; Schiffer, J.P. (eds.)

    1983-10-01

    The appreciation of the role in nuclear physics of the first excited state of the nucleon, the delta ..delta..(1232), has grown rapidly in the past decade. The delta resonance dominates nuclear reactions induced by intermediate energy pions, nucleons, and electromagnetic probes. It is also the most important non-nucleonic degree of freedom needed to resolve many fundamental problems encountered in the study of low-energy nuclear phenomena. Clearly, a new phase of nuclear physics has emerged and conventional thinking must be extended to account for this new dimension of nuclear dynamics. The most challenging problem we are facing is how a unified theory can be developed to describe ..delta..-nucleus dynamics at all energies. In exploring this new direction, it is important to have direct discussions among researchers with different viewpoints. Separate entries were prepared for the 49 papers presented. (WHK)

  18. Dirac phenomenology and hyperon-nucleus interactions

    International Nuclear Information System (INIS)

    We discuss various aspects of hyperon-nucleus interactions in the relativistic mean field theory. First, characteristics of Λ, Σ and ≡ hypernuclei, as well as multi strange baryonic objects, are investigated. The spin-orbit splittings and magnetic moments are shown to be very sensitive to the value of the tensor coupling fωy. Second, optical potentials for Λ and Σ scattering off nuclei are developed based on a global nucleon-nucleon Dirac optical potential and SU(3) symmetry. The tensor coupling has a large effect on the predictions for the analyzing power. Third, the Dirac approach is used in the calculations of the non-mesonic decay of Λ hypernuclei. The large discrepancy between the decay rates and data suggests the need for additional meson exchanges. (authors). 62 refs.,7 figs., 6 tabs

  19. Nature of multiple-nucleus cluster galaxies

    Energy Technology Data Exchange (ETDEWEB)

    Merritt, D.

    1984-05-01

    In models for the evolution of galaxy clusters which include dynamical friction with the dark binding matter, the distribution of galaxies becomes more concentrated to the cluster center with time. In a cluster like Coma, this evolution could increase by a factor of approximately 3 the probability of finding a galaxy very close to the cluster center, without decreasing the typical velocity of such a galaxy significantly below the cluster mean. Such an enhancement is roughly what is needed to explain the large number of first-ranked cluster galaxies which are observed to have extra ''nuclei''; it is also consistent with the high velocities typically measured for these ''nuclei.'' Unlike the cannibalism model, this model predicts that the majority of multiple-nucleus systems are transient phenomena, and not galaxies in the process of merging.

  20. Suprachiasmatic Nucleus: Cell Autonomy and Network Properties

    Science.gov (United States)

    Welsh, David K.; Takahashi, Joseph S.; Kay, Steve A.

    2013-01-01

    The suprachiasmatic nucleus (SCN) is the primary circadian pacemaker in mammals. Individual SCN neurons in dispersed culture can generate independent circadian oscillations of clock gene expression and neuronal firing. However, SCN rhythmicity depends on sufficient membrane depolarization and levels of intracellular calcium and cAMP. In the intact SCN, cellular oscillations are synchronized and reinforced by rhythmic synaptic input from other cells, resulting in a reproducible topographic pattern of distinct phases and amplitudes specified by SCN circuit organization. The SCN network synchronizes its component cellular oscillators, reinforces their oscillations, responds to light input by altering their phase distribution, increases their robustness to genetic perturbations, and enhances their precision. Thus, even though individual SCN neurons can be cell-autonomous circadian oscillators, neuronal network properties are integral to normal function of the SCN. PMID:20148688

  1. Laser-Nucleus Interactions: The Quasiadiabatic Regime

    CERN Document Server

    Pálffy, Adriana; Hoefer, Axel; Weidenmüller, Hans A

    2015-01-01

    The interaction between nuclei and a strong zeptosecond laser pulse with coherent MeV photons is investigated theoretically. We provide a first semi-quantitative study of the quasiadiabatic regime where the photon absorption rate is comparable to the nuclear equilibration rate. In that regime, multiple photon absorption leads to the formation of a compound nucleus in the so-far unexplored regime of excitation energies several hundred MeV above the yrast line. The temporal dynamics of the process is investigated by means of a set of master equations that account for dipole absorption, stimulated dipole emission, neutron decay and induced fission in a chain of nuclei. That set is solved numerically by means of state-of-the-art matrix exponential methods also used in nuclear fuel burnup and radioactivity transport calculations. Our quantitative estimates predict the excitation path and range of nuclei reached by neutron decay and provide relevant information for the layout of future experiments.

  2. High energy hadron-nucleus collision

    International Nuclear Information System (INIS)

    This is a lecture note concerning high energy hadron-nucleus collision. The lecture gives the inelastic total cross section and the Glanber approximate multiple scattering formula at first. The mechanism of nuclear spallation is described in a cylindrical image. The multiplicity, the one particle distribution and the time-space structure of particle production are discussed. Various models are presented. The attenuation of forward particles and the structure of hadrons are discussed for each model. The atomic number (A) dependence of the production of large transverse momentum particles and jet, and the A dependence of charged multiplicity are presented. The backward production of particles and many body correlation are discussed. Lepton pair production and the initial interaction of constituents, collective interaction, multi quark state and phase transition are described. (Kato, T.)

  3. Delta-nucleus dynamics: proceedings of symposium

    International Nuclear Information System (INIS)

    The appreciation of the role in nuclear physics of the first excited state of the nucleon, the delta Δ(1232), has grown rapidly in the past decade. The delta resonance dominates nuclear reactions induced by intermediate energy pions, nucleons, and electromagnetic probes. It is also the most important non-nucleonic degree of freedom needed to resolve many fundamental problems encountered in the study of low-energy nuclear phenomena. Clearly, a new phase of nuclear physics has emerged and conventional thinking must be extended to account for this new dimension of nuclear dynamics. The most challenging problem we are facing is how a unified theory can be developed to describe Δ-nucleus dynamics at all energies. In exploring this new direction, it is important to have direct discussions among researchers with different viewpoints. Separate entries were prepared for the 49 papers presented

  4. Electron-Nucleus Collisions at THERA

    CERN Document Server

    Frankfurt, L L; McDermott, M; Strikman, M I

    2001-01-01

    The nuclear option at THERA provides an ideal and unique opportunity to investigate the black body limit (BBL) of high energy Deep Inelastic Scattering of highly virtual photons off heavy nuclear targets and thereby probe QCD in a new regime. At high enough energies, whichever hadronic configuration the photon fluctuates into, the interaction at a given impact parameter with the heavy nuclear target will eventually reach its geometrical limit corresponding to the scattering from a black disk. An attractive feature of the BBL regime for a large nucleus is that the interaction is strong although the coupling constant is small. Predictions for longitudinal and transverse distributions of the leading hadrons in inclusive and diffractive channels and exclusive vector meson production are found to be strikingly different in BBL and the leading twist approximation. In particular, the multiplicity of leading hadrons in the current fragmentation region is strongly suppressed, while the cross section of diffractive vec...

  5. The Cuspy LINER Nucleus of the S0/a Galaxy NGC 2681

    CERN Document Server

    Cappellari, M; Burstein, D; Buson, L M; Greggio, L; Renzini, A; Cappellari, Michele; Bertola, Francesco; Burstein, David; Buson, Lucio M.; Greggio, Laura; Renzini, Alvio

    2001-01-01

    The nucleus of the bulge-dominated, multiply-barred S0/a galaxy NGC 2681 is studied in detail, using high resolution Hubble Space Telescope FOC and NICMOS imaging and FOS spectroscopy. The ionised gas central velocity dispersion is found to increase by a factor ~2 when narrowing the aperture from R~1.5" (ground) to R~0.1" (FOS). Dynamical modeling of these velocity dispersions suggests that NGC 2681 does host a supermassive black hole (BH) for which one can estimate a firm mass upper limit M_BH < 6*10^7 Solar Masses. This upper limit is consistent with the relation between the central BH mass and velocity dispersion M_BH - sigma known for other galaxies. The emission line ratios place the nucleus of NGC 2681 among LINERs. It is likely that the emission line region comes from a rather mild, but steady, feeding of gas to the central BH in this galaxy. The inner stellar population lacks any measurable color gradient (to a radius of 0.6 kpc) from the infrared to the ultraviolet, consistently with FOC, FOS and ...

  6. [Central auditory prosthesis].

    Science.gov (United States)

    Lenarz, T; Lim, H; Joseph, G; Reuter, G; Lenarz, M

    2009-06-01

    Deaf patients with severe sensory hearing loss can benefit from a cochlear implant (CI), which stimulates the auditory nerve fibers. However, patients who do not have an intact auditory nerve cannot benefit from a CI. The majority of these patients are neurofibromatosis type 2 (NF2) patients who developed neural deafness due to growth or surgical removal of a bilateral acoustic neuroma. The only current solution is the auditory brainstem implant (ABI), which stimulates the surface of the cochlear nucleus in the brainstem. Although the ABI provides improvement in environmental awareness and lip-reading capabilities, only a few NF2 patients have achieved some limited open set speech perception. In the search for alternative procedures our research group in collaboration with Cochlear Ltd. (Australia) developed a human prototype auditory midbrain implant (AMI), which is designed to electrically stimulate the inferior colliculus (IC). The IC has the potential as a new target for an auditory prosthesis as it provides access to neural projections necessary for speech perception as well as a systematic map of spectral information. In this paper the present status of research and development in the field of central auditory prostheses is presented with respect to technology, surgical technique and hearing results as well as the background concepts of ABI and AMI. PMID:19517084

  7. Total inclusive neutron cross sections and multiplicities in nucleus-nucleus collisions at intermediate energies

    International Nuclear Information System (INIS)

    The total integrated inclusive cross section, sigma(T>T0), for the emission of neutrons above an energy T0 by neon ions with an average energy of 337 MeV per nucleon reacting in targets of uranium, copper, aluminum, and carbon is described by sigma-bar/sub NN/(R-bar/sub G//r/sub o/)/sup( alphaT/o). Here sigma-bar/sub NN/ is the isospin-averaged nucleon-nucleon cross section evaluated at an energy equal to the bombarding energy per nucleon, and R-bar/sub G/ is the arithmetic mean value of the radii of the projectile and the target measured in units of the radius parameter r0 ( = 1.2 fm). In the limit T0 = 0, the exponent α(T0) = 5. A useful formula is derived for calculating mean neutron multiplicities in nucleus-nucleus collisions

  8. Production of cold fragments in nucleus-nucleus collisions in the Fermi-energy domain

    CERN Document Server

    Veselsky, M

    2007-01-01

    The reaction mechanism of nucleus-nucleus collisions at projectile energies around the Fermi energy is investigated with emphasis on the production of fragmentation-like residues. The results of simulations are compared to experimental mass distributions of elements with Z = 21 - 29 observed in the reactions 86Kr+124,112Sn at 25 AMeV. The model of incomplete fusion is modified and a component of excitation energy of the cold fragment dependent on isospin asymmetry is introduced. The modifications in the model of incomplete fusion appear consistent with both overall model framework and available experimental data. A prediction is provided for the production of very neutron-rich nuclei using a secondary beam of 132Sn where e.g. the reaction 132Sn+238U at 28 AMeV appears as a possible alternative to the use of fragmentation reactions at higher energies.

  9. Experimental and phenomenological investigations of QCD matter in high-energy nucleus-nucleus collisions

    International Nuclear Information System (INIS)

    This thesis is heterogeneous, comprising experimental papers at low energies (SIS-18 at GSI) and at the LHC, papers on phenomenology of high-energy nucleus-nucleus collisions, and papers on detectors. The overview covers the experimental papers and those on phenomenology. I have chosen to write it in a general manner, intended to be accessible to non-experts. It emphasizes recent measurements and their understanding at the LHC. The detector papers, which address many principle aspects of gaseous detectors, are summarized and placed in context in the review I co-wrote and which closes the stack. The detector papers included here are the outcome of an R and D program for the Transition Radiation Detector of ALICE.

  10. Experimental and phenomenological investigations of QCD matter in high-energy nucleus-nucleus collisions

    Energy Technology Data Exchange (ETDEWEB)

    Andronic, Anton

    2014-07-15

    This thesis is heterogeneous, comprising experimental papers at low energies (SIS-18 at GSI) and at the LHC, papers on phenomenology of high-energy nucleus-nucleus collisions, and papers on detectors. The overview covers the experimental papers and those on phenomenology. I have chosen to write it in a general manner, intended to be accessible to non-experts. It emphasizes recent measurements and their understanding at the LHC. The detector papers, which address many principle aspects of gaseous detectors, are summarized and placed in context in the review I co-wrote and which closes the stack. The detector papers included here are the outcome of an R and D program for the Transition Radiation Detector of ALICE.

  11. Nonmonotonic Target Excitation Dependence of Pion Clans in Relativistic Nucleus-Nucleus Collisions

    Science.gov (United States)

    Ghosh, Dipak; Deb, Argha; Dutta, Srimonti

    Target excitation dependence of fluctuation of produced pions (i.e. classifying data of the fluctuation pattern on pions on the basis of the number of gray tracks) is studied for nucleus-nucleus collisions at different projectile energies. In each set the experimental multiplicity distribution is compared with the negative binomial distribution (NBD), which is found to describe the experimental distribution quite well. Target excitation dependence is studied in respect of the clan model parameters bar {n}c and bar {N}, which are extracted from the NBD fit parameters bar {n} and k. A detailed comparison between different interactions at the same energy and the same interactions at different energies is also drawn. A nonmonotonic dependence of D2/bar {n} on is revealed, which is also a characteristic of multiplicity fluctuations at RHIC data.

  12. Nuclear Effects in Neutrino-Nucleus Interactions and the MINERvA Neutrino Nucleus Scattering Program

    International Nuclear Information System (INIS)

    Nuclear effects of charged current deep inelastic neutrino-iron scattering have been studied in the frame-work of a χ2 analysis of parton distribution functions (PDFs)1. A set of iron PDFs have been extracted which are then used to compute xBj-dependent and Q2-dependent nuclear correction factors for iron structure functions which are required in global analyses of free nucleon PDFs. Upon comparing our results with nuclear correction factors from neutrino-nucleus scattering models and correction factors for l±-iron scattering we find that, except for very high xBj, our correction factors differ in both shape and magnitude from the correction factors of the models and charged-lepton scattering. The MINERvA neutrino-nucleus scattering experiment at Fermilab, will systematically study neutrino nuclear effects off of He, C, Fe and Pb for a more thorough A-dependent study of nuclear PDFs and these correction factors.

  13. Dissipation and fluctuation of the relative momentum in nucleus-nucleus collisions

    International Nuclear Information System (INIS)

    The dissipation of the relative momentum in nucleus-nucleus collisions is treated in terms of a Langevin equation with a fluctuating force. Equations of motion for first and second moments of the macroscopic variables are derived directly from the Langevin equation. The properties of the fluctuating force which results from random particle exchange are investigated in detail. Drift and diffusion coefficients are calculated microscopically and analytical expressions are given which can be used in any trajectory calculation. An important feature of the model is that the Einstein relation between dissipation and fluctuation turns out to be only a limiting case of a more general expression which included nonthermal fluctuations. By treating the two nuclei as intrinsically equilibrated but not in thermal equilibrium with respect to each other several important aspects of the dissipative behaviour, seen in heavy ion collisions with final energies above the Coloumb barrier, can be understood. (orig.)

  14. Recent Developments in the Study of Deconfinement in Nucleus-Nucleus Collisions

    CERN Document Server

    Gazdzicki, M; Seyboth, P

    2014-01-01

    Deconfinement refers to the creation of a state of quasi-free quarks and gluons in strongly interacting matter. Model predictions and experimental evidence for the onset of deconfinement in nucleus-nucleus collisions were discussed in our first review on this subject. These results motivated further experimental and theoretical studies. This review addresses two subjects. First, a summary of the past, present and future experimental programmes related to discovery and study of properties of the onset of deconfinement are %briefly presented. Second, recent progress is reviewed on analysis methods and preliminary experimental results for new strongly intensive fluctuation measures are discussed, which are relevant for current and future studies of the onset of deconfinement and searches for the critical point of strongly interacting matter

  15. Stopping in high energy nucleus-nucleus collisions in the RQMD-approach

    International Nuclear Information System (INIS)

    The most intensely studied questions of today's high energy nuclear physics is that of the transition of normal nuclear matter to a quark gluon plasma state (QGP). The phase transition should occur in probes of nuclear matter of very high temperature and density. It is generally believed that these circumstances should preferentially occur in collisions of heavy nuclei with high energies. This question is considered giving a hint to the direction which has to be taken first in order to obtain answers to the question of QGP. The behaviour of two large nuclei which collide with high relative momentum is investigated. Comparisons are shown between RQMD and CERN-SPS experiments and it was found that the RQMD calculations of nucleus-nucleus collisions are in nearly perfect agreement with the available experimental data. (R.P.) 17 refs.; 6 figs

  16. Jet energy loss and bulk parton collectivity in nucleus-nucleus collisions at RHIC

    Institute of Scientific and Technical Information of China (English)

    HUANG Huan-Zhong

    2009-01-01

    Nucleus-nucleus collisions at RHIC produce high temperature and high energy density matter which exhibits paxtonic degrees of freedom. We will discuss measurements of nuclear modification factors for light hadrons and non-photonic electrons from heavy quark decays, which reflect the flavor dependence of energy loss of high momentum partons traversing the dense QCD medium. The dense QCD medium responds to energy loss of high momentum patrons in a pattern consistent with that expected from a hydrodynamic fluid. The hadronization of bulk partonic matter exhibits collectivity with effective partonic degrees of freedom. Nuclear collisions at RHIC provide an intriguing environment, where many constituent quark ingredients are readily available for possible formation of exotic particles through quark coalescence or recombinations.

  17. A Heuristic Model for the Active Galactic Nucleus Based on the Planck Vacuum Theory

    Directory of Open Access Journals (Sweden)

    Daywitt W. C.

    2009-07-01

    Full Text Available The standard explanation for an active galactic nucleus (AGN is a "central engine" consisting of a hot accretion disk surrounding a supermassive black hole. Energy is generated by the gravitational infall of material which is heated to high temperatures in this dissipative accretion disk. What follows is an alternative model for the AGN based on the Planck vacuum (PV theory, where both the energy of the AGN and its variable luminosity are explained in terms of a variable photon flux emanating from the PV.

  18. A Heuristic Model for the Active Galactic Nucleus Based on the Planck Vacuum Theory

    Directory of Open Access Journals (Sweden)

    Daywitt W. C.

    2009-07-01

    Full Text Available The standard explanation for an active galactic nucleus (AGN is a “central engine” consisting of a hot accretion disk surrounding a supermassive black hole [1, p. 32]. Energy is generated by the gravitational infall of material which is heated to high tem- peratures in this dissipative accretion disk. What follows is an alternative model for the AGN based on the Planck vacuum (PV theory [2, Appendix], where both the energy of the AGN and its variable luminosity are explained in terms of a variable photon flux emanating from the PV.

  19. Effects of anesthetics on ponto-geniculo-occipital waves from the oculomotor nucleus of the cat.

    Science.gov (United States)

    Yanagida, H; Ashizawa, N; Wakushima, Y; Yamamura, H

    1975-05-01

    Effects of anesthetics and doxapram on pontogeniculo-occipital (PGO) waves from the oculomotor nucleus were studied in acute experiments in cats paralyzed by gallamine triethiodide. The anesthetic agents studied in the present experiment (thiopental, ketamine, Innovar, nitrous oxide, and halothane) decreased, while doxapram increased, the total number of PGO waves. As the doses of anesthetics increased, PGO waves were abolished, but they returned to control levels or below control levels when the concentrations of anesthetics were decreased. The results indicate that the anesthetics studied inhibit the activity of the central mechanism associated with the oculomotor system. PGO waves may prove a useful index of the level of anesthesia. PMID:1130723

  20. Nucleus -nucleus interactions at a few GeV/C per nucleon

    International Nuclear Information System (INIS)

    Introduction: Since the period of the ancient Egyptians people are looking for unusual phenomena, which may enable to give interpretation for nature. Physicists believe that the study of A-A interactions will shed light on the mechanism of high-energy nuclear interactions. It is important to systematize the results of nucleus-nucleus interactions and to have an overall picture of cross-section, multiplicity-distributions, angular distributions, etc It is important to systematize the results of nucleus-nucleus interactions and to have an overall picture of: cross-section, multiplicity-distributions, angular distributions, etc Beams: Beams are mainly from Dubna Synchrophasotron including 1H, 2H, 3He, 4He, 12C, 160,22Ne, 24Mg, 28Si and 32S at 4.1∼ 4.5 GeV/c. Experimental Technique: Stacks of Br-2 emulsion were exposed to 4.1- 4.5 A GeV/c nuclei at Dubna Synchrophasotron. The pellicles of emulsion have the dimensions of 20 cm x 10 cm x 600 μm (undeveloped emulsion). The intensity of the beam was ≡104 particles/cm2 and the beam diameter was approximately 1 cm. The emitted particles are classified to:Shower tracks producing s-particleshaving a relative ionization I*≤ 1.4. Its multiplicity is denoted by ns after the exclusion of tracks having an emission angle θ≤3ο.Grey tracks producing g-particleshaving I* > 1.4 and L>3 mm. Its multiplicity is denoted by ng and does not include those tracks with an emission angle θ≤ 3ο. Black tracks producing b-particleshaving L b and does not include those tracks having an angle of emission θ≤3ο.The band gtracks are both called heavily ionizing tracks producing h-particlesand nh denotes its multiplicity

  1. The Confined Hydrogen Atom with a Moving Nucleus

    Science.gov (United States)

    Fernandez, Francisco M.

    2010-01-01

    We study the hydrogen atom confined to a spherical box with impenetrable walls but, unlike earlier pedagogical articles on the subject, we assume that the nucleus also moves. We obtain the ground-state energy approximately by means of first-order perturbation theory and show that it is greater than that for the case in which the nucleus is clamped…

  2. A Frame Nucleus on a Two-side Prequantale

    Institute of Scientific and Technical Information of China (English)

    XUShao-xian; WANGShun-qin; MAFei-fei

    2004-01-01

    In this paper, a Frame nucleus and prime elements in a Prequantale are defined. The concrete structure of a Frame prequantic quotient is considered, and the relation between the half-prime element and the Frame nucleus in a two-side Prequantale are obtained.

  3. Europa central

    Directory of Open Access Journals (Sweden)

    Karel BARTOSEK

    2010-02-01

    Full Text Available La investigación francesa continúa interesándose por Europa Central. Desde luego, hay límites a este interés en el ambiente general de mi nueva patria: en la ignorancia, producto del largo desinterés de Francia por este espacio después de la Segunda Guerra Mundial, y en el comportamiento y la reflexión de la clase política y de los medios de comunicación (una anécdota para ilustrar este ambiente: durante la preparación de nuestro coloquio «Refugiados e inmigrantes de Europa Central en el movimiento antifascista y la Resistencia en Francia, 1933-1945», celebrado en París en octubre de 1986, el problema de la definición fue planteado concreta y «prácticamente». ¡Y hubo entonces un historiador eminente, para quién Alemania no formaría parte de Europa Central!.

  4. Repeated, recent and diverse transfers of a mitochondrial gene to the nucleus in flowering plants.

    Science.gov (United States)

    Adams, K L; Daley, D O; Qiu, Y L; Whelan, J; Palmer, J D

    2000-11-16

    A central component of the endosymbiotic theory for the bacterial origin of the mitochondrion is that many of its genes were transferred to the nucleus. Most of this transfer occurred early in mitochondrial evolution; functional transfer of mitochondrial genes has ceased in animals. Although mitochondrial gene transfer continues to occur in plants, no comprehensive study of the frequency and timing of transfers during plant evolution has been conducted. Here we report frequent loss (26 times) and transfer to the nucleus of the mitochondrial gene rps10 among 277 diverse angiosperms. Characterization of nuclear rps10 genes from 16 out of 26 loss lineages implies that many independent, RNA-mediated rps10 transfers occurred during recent angiosperm evolution; each of the genes may represent a separate functional gene transfer. Thus, rps10 has been transferred to the nucleus at a surprisingly high rate during angiosperm evolution. The structures of several nuclear rps10 genes reveal diverse mechanisms by which transferred genes become activated, including parasitism of pre-existing nuclear genes for mitochondrial or cytoplasmic proteins, and activation without gain of a mitochondrial targeting sequence. PMID:11099041

  5. TRH injected into the nucleus accumbens shell releases dopamine and reduces feeding motivation in rats.

    Science.gov (United States)

    Puga, L; Alcántara-Alonso, V; Coffeen, U; Jaimes, O; de Gortari, P

    2016-06-01

    The thyrotropin-releasing hormone (TRH), an anorexigenic factor that reduces food intake in food-restricted animals, may be involved in motivation for food. Injected centrally, TRH impairs acquisition of food-rewarded behavior. Through the TRH-R1 receptors, TRH injected in the nucleus accumbens increases dopamine content-perhaps the mechanism by which the peptide modulates food motivation. This, however, is still to be demonstrated. We sought to evaluate dopamine release by microdialysis after a TRH injection into the nucleus accumbens shell in free-moving fasted rats. In addition, we assessed dopamine content and turnover by HPLC and the relationship with the motivation for food by analyzing the performance of rats during a progressive-ratio (PR) operant-conditioning test. Finally, we determined serum leptin and triiodothyronine (T3) levels in order to evaluate the animals' metabolic response to food restriction and the impact of intra-accumbal TRH administration on circulating hormones. Intra-accumbal injections of TRH reduced food intake in food-restricted rats-compared to counterparts treated with saline-, without further decreasing T3 or leptin levels, which dropped due to their dietary regime. TRH-injected rats had lower breaking points on the PR schedule, which indicated lower motivation to eat. Accordingly, compared to saline-treated animals, dopamine release and turnover increased in the nucleus accumbens of TRH-injected rats, a finding that suggests a relationship between motivation for food and TRH-induced release of dopamine. PMID:27006143

  6. Conserved Expression of the Glutamate NMDA Receptor 1 Subunit Splice Variants during the Development of the Siberian Hamster Suprachiasmatic Nucleus

    OpenAIRE

    Duffield, Giles E.; Jens D Mikkelsen; Ebling, Francis J. P.

    2012-01-01

    Glutamate neurotransmission and the N-methyl-D-aspartate receptor (NMDAR) are central to photic signaling to the master circadian pacemaker located in the hypothalamic suprachiasmatic nucleus (SCN). NMDARs also play important roles in brain development including visual input circuits. The functional NMDAR is comprised of multiple subunits, but each requiring the NR1 subunit for normal activity. The NR1 can be alternatively spliced to produce isoforms that confer different functional propertie...

  7. CaMKII Activity in the Ventral Tegmental Area Gates Cocaine-Induced Synaptic Plasticity in the Nucleus Accumbens

    OpenAIRE

    Liu, Xiaojie; Liu, Yong; Zhong, Peng; Wilkinson, Brianna; Qi, Jinshun; Olsen, Christopher M; Bayer, K. Ulrich; Liu, Qing-song

    2013-01-01

    Addictive drugs such as cocaine induce synaptic plasticity in discrete regions of the reward circuit. The aim of the present study is to investigate whether cocaine-evoked synaptic plasticity in the ventral tegmental area (VTA) and nucleus accumbens (NAc) is causally linked. Ca2+/calmodulin-dependent protein kinase II (CaMKII) is a central regulator of long-term synaptic plasticity, learning, and drug addiction. We examined whether blocking CaMKII activity in the VTA affected cocaine conditio...

  8. Medial nucleus tractus solitarius oxytocin receptor signaling and food intake control: the role of gastrointestinal satiation signal processing

    OpenAIRE

    Ong, Zhi Yi; Alhadeff, Amber L; Grill, Harvey J.

    2015-01-01

    Central oxytocin (OT) administration reduces food intake and its effects are mediated, in part, by hindbrain oxytocin receptor (OT-R) signaling. The neural substrate and mechanisms mediating the intake inhibitory effects of hindbrain OT-R signaling are undefined. We examined the hypothesis that hindbrain OT-R-mediated feeding inhibition results from an interaction between medial nucleus tractus solitarius (mNTS) OT-R signaling and the processing of gastrointestinal (GI) satiation signals by n...

  9. Caudal Nuclei Of The Rat Nucleus Of The Solitary Tract Differentially Innervate Respiratory Compartments Within The Ventrolateral Medulla

    OpenAIRE

    Alheid, George F.; Jiao, Weijie; McCrimmon, Donald R.

    2011-01-01

    A substantial array of respiratory, cardiovascular, visceral and somatic afferents are relayed via the nucleus of the solitary tract (NTS) to the brainstem (and forebrain). Despite some degree of overlap within the NTS, specificity is maintained in central respiratory reflexes driven by 2nd order afferent relay neurons in the NTS. While the topographical arrangement of respiratory-related afferents targeting the NTS has been extensively investigated, their higher order brainstem targets beyon...

  10. Distribution of Hypophysiotropic Thyrotropin-Releasing Hormone (TRH)-Synthesizing Neurons in the Hypothalamic Paraventricular Nucleus of the Mouse

    OpenAIRE

    Kádár, Andrea; Sánchez, Edith; Wittmann, Gábor; Singru, Praful S.; Füzesi, Tamás; Marsili, Alessandro; Larsen, P. Reed; Liposits, Zsolt; Lechan, Ronald M.; Fekete, Csaba

    2010-01-01

    Hypophysiotropic thyrotropin-releasing hormone (TRH) neurons, the central regulators of the hypothalamus-pituitary-thyroid axis, are located in the hypothalamic paraventricular nucleus (PVN) in a partly overlapping distribution with non-hypophysiotropic TRH neurons. The distribution of hypophysiotropic TRH neurons in the rat PVN is well understood, but the localization of these neurons is unknown in mice. To determine the distribution and phenotype of hypophysiotropic TRH neurons in mice, dou...

  11. Differentiation of autonomic reflex control begins with cellular mechanisms at the first synapse within the nucleus tractus solitarius

    OpenAIRE

    Andresen M.C.; Doyle M.W.; Bailey T.W.; Jin Y.-H.

    2004-01-01

    Visceral afferents send information via cranial nerves to the nucleus tractus solitarius (NTS). The NTS is the initial step of information processing that culminates in homeostatic reflex responses. Recent evidence suggests that strong afferent synaptic responses in the NTS are most often modulated by depression and this forms a basic principle of central integration of these autonomic pathways. The visceral afferent synapse is uncommonly powerful at the NTS with large unitary response amplit...

  12. Nucleus Paragigantocellularis Afferents in Male and Female Rats: Organization, Gonadal Steroid Sensitivity, and Activation During Sexual Behavior

    OpenAIRE

    Normandin, Joseph J.; Murphy, Anne Z.

    2008-01-01

    The central regulation of genital reflexes is poorly understood. The brainstem nucleus paragigantocellularis (nPGi) of rats is a well-established source of tonic inhibition of genital reflexes. However the organization, gonadal steroid sensitivity, and activity of nPGi afferents during sex have not been fully characterized in male and female rats. To delineate the anatomical and physiological organization of nPGi afferents, the retrograde tracer Fluorogold (FG) was injected into the nPGi of s...

  13. Δ33 resonance in pion nucleus elastic, single, and double charge exchange scattering

    International Nuclear Information System (INIS)

    The Δ33 resonance is strongly excited in pion-nucleon scattering, but there is clearly only a limited amount of information that can be learned in scattering the pion from an isolated nucleon. One learns that there is a resonance of mass 1232 MeV, width 115 MeV, and, if one is willing to introduce a dynamical model, something about the off-shell extension of the amplitude. One stands to learn much more from pion-nucleus scattering because in this case the Δ33 resonance has an opportunity to scatter from nucleons, and how this occurs is not well understood. What do we know about the Δ-N interaction for pion-nucleus scattering. The isobar-hole model was invented to deal directly with the Δ33-nucleus dynamics, and a phenomenological determination of the isobar shell-model potential was attempted. The unknown dynamics deltaU/sub Δ/ is contained in a central isoscalar spreading potential of strength W0 and a spin orbit potential deltaU0 = W0rho + spin-orbit. The real part of W0rho is measured relative to the nucleon-nucleus potential. From a more theoretical point of view, one would like to be able to calculate deltaU/sub Δ/, including its isospin dependence, from an underlying dynamical model which is formulated in terms of the basic effective meson-baryon couplings. Some salient properties of these couplings can be determined from models of quark-bag structure, which raises the exciting possibility of learning about these fundamental issues from pion scattering. Attempts at Los Alamos to build a theoretical framework to deal with these and other issues are described

  14. The new magic nucleus 96Zr

    International Nuclear Information System (INIS)

    The 96Zr nucleus is expected to be magic due to the subshell closures at Z = 40 and N = 56. Recent gamma-spectroscopic studies involving in-beam techniques and beta decay certainly revealed a remarkably simple level pattern consisting of the 1,750 keV 2+ - 2,439 keV 3+ doublet, a few levels decaying to the 3- octupole state by strong E1 or E2 transitions, and a band built on the shape isomeric first excited 0+ state. While quadrupole vibrational collectivity is restricted to this latter intruder band the octupole mode is expected to be strong, according to systematics and an earlier lifetime result for the 3- state. since low-lying particle-hole excitations, and a strong octupole mode in particular, are typical for magic nuclei like 208Pb it is important to test to what extent 96Zr resembles the well known magic nuclei. In this paper, inelastic deuteron scattering and RPA studies show that the lowest states of doubly closed subshell 96Zr are particle-hole excitations, the first 2+ state being a neutron excitation of 3s1/2 2d5/2-1 type. The octupole collectively is enhanced by a factor of about two with respect to 90Zr due mainly to the contribution of 1h1 1/2 2d5/2-1 neutron excitations, suggesting an unusually high B(E3) value

  15. 34Si: a new doubly magic nucleus

    International Nuclear Information System (INIS)

    The 34Al β decay was studied at the CERN on-line mass separator ISOLDE. Gamma-ray singles, β-γ, and β-γ-γ coincidence measurements, were registered with two 80% Ge detectors. A 34Al β-decay scheme to 34Si bound states is established. The first level scheme in 34Si includes three levels at 3327.7 ± 0.5, 4257.3 ± 0.4 and 4382.7 ± 0.7 keV with respectively a Jπ assignment of 2+, 3- and (4,5)-. The 34Si level scheme is consistent with the assignment of Jπ=4- for the34Al ground state. The value of P1n=0.27(5) has been deduced for the β-delayed 1n emission of 34Al. The 34Si level scheme is found to agree with the present shell-model predictions. In the resulting picture, 34Si appears to be a new doubly magic nucleus

  16. The Chemical Evolution of Starburst Nucleus Galaxies

    CERN Document Server

    Coziol, R; Davoust, E; Considère, S

    1997-01-01

    The metallicities derived from spectroscopic observations of a sample of Starburst Nucleus Galaxies (SBNGs) are compared to those of several other types of galaxies (normal giant galaxies, Irregular and HII galaxies) drawn from the literature. The SBNGs are deficient in metals with respect to normal galaxies of same morphological type, suggesting that - SBNGs are galaxies still in the process of formation. Breaking the SBNGs into early-types (Sb and earlier) and late-types reveals that the former seem to follow the same linear luminosity-metallicity relation as the irregular and elliptical galaxies, whereas the latter and the giant spirals show comparable (0.2 and 0.3 dex) excess abundances with respect to the linear relation. This difference between the two types of SBNGs is consistent with the predictions of the model of hierarchical formation of galaxies: the early-type SBNGs are building their bulges by successive mergers of small stellar and gaseous systems, while the late-type SBNGs are mostly accreting...

  17. Spontaneous fission of superheavy nucleus $^{286}$Fl

    CERN Document Server

    Poenaru, Dorin N

    2016-01-01

    The decimal logarithm of spontaneous fission half-life of the superheavy nucleus $^{286}$Fl experimentally determined is $\\log_{10} T_f^{exp} (s) = -0.632$. We present a method to calculate the half-life based on the cranking inertia and the deformation energy, functions of two independent surface coordinates, using the best asymmetric two center shell model. In the first stage we study the statics. At a given mass asymmetry up to about $\\eta=0.5$ the potential barrier has a two hump shape, but for larger $\\eta$ it has only one hump. The touching point deformation energy versus mass asymmetry shows the three minima, produced by shell effects, corresponding to three decay modes: spontaneous fission, cluster decay and $\\alpha$~decay. The least action trajectory is determined in the plane $(R,\\eta)$ where $R$ is the separation distance of the fission fragments and $\\eta$ is the mass asymmetry. We may find a sequence of several trajectories one of which gives the least action. The parametrization with two deforma...

  18. Gabapentin inhibits central sensitization during migraine

    Institute of Scientific and Technical Information of China (English)

    Yanbo Zhang; Guo Shao; Wei Zhang; Sijie Li; Jingzhong Niu; Dongmei Hu; Mingfeng Yang; Xunming Ji

    2013-01-01

    Peripheral and central sensitizations are phenomena that occur during migraine. The role of pentin, a migraine preventive drug, on central sensitization remains unclear. In this study, a rat model of migraine was established by electrical stimulation of the trigeminal ganglion, and the an-imals were given intragastric gabapentin. Changes in amino acid content in the cerebrospinal fluid and protein kinase C membrane translocation in the spinal trigeminal nucleus were examined to clarify the mechanisms underlying the efficacy of gabapentin in the treatment of central sensitization during migraine. Electrophysiology, liquid chromatography-mass spectrometry and western blot analysis results revealed that gabapentin reduces neuronal excitability in the spinal nucleus in the trigeminal nerve, decreases excitatory amino acid content and inhibits the activation of protein ki-nase C. This provides evidence that excitatory amino acids and protein kinase C are involved in the formation and maintenance of central sensitization during migraine. Gabapentin inhibits migraine by reducing excitatory amino acid content in the cerebrospinal fluid and inhibiting protein kinase C ac-tivation.

  19. Bose-Einstein correlations in the target fragmentation region of 200 A GeV 16O + nucleus collisions

    International Nuclear Information System (INIS)

    Correlations of positive pions are investigated in the target fragmentation region of 200 A GeV 16O + nucleus collisions. The pions are measured with the Plastic Ball detectors in the WA80 experiment at the CERN SPS. The detailed behaviour of the fitted parameters on rapidity, centrality and the number of spectator nucleons is studied. The data indicate a large source in central O + Au collisions for ylab ≤ 0. The observations are compatible with a substantial amount of rescattering in the target. (orig.)

  20. Antiproton-nucleus interaction: review of the experimental situation

    International Nuclear Information System (INIS)

    This paper will review the experimental situation of a few well-defined channels of the anti-p-nucleus interaction where the antiproton does not annihilate. It will not mention any experiment which studies annihilation of antiporotons in nuclei. The anti-p-nucleus reactions that will be reviewed are the following: 1. A(anti-p,anti-p)A elastic scattering which deals with the anti-p-nucleus system in a positive energy state. 2. Anti-p-nucleus atoms where the anti-p-nucleus system is almost at zero energy and interacts mostly through the Coulomb interaction, the strong interaction being only a perturbation. 3. A(anti-p,p)X proton knock-out reaction used to produce possible bound states or resonances of the anti-p-nucleus system via strong interaction. The main reasons for studying these three channels are to provide information about the anti-p-nucleus optical potential and also, through microscopic calculations which use the elementary anti-NN amplitudes and the nuclear matter densities as inputs, to get information about these quantities. 4. A(anti-p,anti-p')A* inelastic scattering - inelastic in the sense that the nucleus is left in an excited state but the antiproton does not annihilate, that is it deals only with the elastic part of the elementary anti-NN amplitude. Inelastic scattering from collective states also sets constraints on the anti-p-nucleus potential when analysed in terms of coupled-channel calculations. When unnatural parity states are concerned, it provides a sensitive test of the spin and isospin components of these amplitudes. In addition, this paper will focus essentially on the recent experiments performed at LEAR

  1. Gluon production from non-Abelian Weizsaecker-Williams fields in nucleus-nucleus collisions

    Energy Technology Data Exchange (ETDEWEB)

    Kovner, A.; McLerran, L.; Weigert, H. [School of Physics and Astronomy, University of Minnesota, Minneapolis, Minnesota 55455 (United States)

    1995-12-01

    We consider the collisions of large nuclei using the theory of McLerran and Venugopalan. The two nuclei are ultrarelativistic and sources of non-Abelian Weizseacker-Williams fields. These sources are in the end averaged over all color orientations locally with a Gaussian weight. We show that there is a solution of the equations of motion for the two nucleus scattering problem where the fields are time and rapidity independent before the collision. After the collision the solution depends on proper time, but is independent of rapidity. We show how to extract the produced gluons from the classical evolution of the fields.

  2. Nonthermal Fluctuations and Mechanics of the Active Cell Nucleus

    CERN Document Server

    Smith, K; Byrd, H; MacKintosh, F C; Kilfoil, M L

    2013-01-01

    We present direct measurements of fluctuations in the nucleus of yeast cells. While prior work has shown these fluctuations to be active and non-thermal in character, their origin and time dependence are not understood. We show that nuclear fluctuations can be quantitatively understood by uncorrelated, active force fluctuations driving a nuclear medium that is dominated by an uncondensed DNA solution, for which we perform rheological measurements on an in vitro model system under similar conditions to what is expected in the nucleus. We conclude that the eukaryotic nucleus of living cells is a nonequilibrium soft material whose fluctuations are actively driven, and are far from thermal in their time dependence.

  3. Quarkonium-nucleus bound states from lattice QCD

    Energy Technology Data Exchange (ETDEWEB)

    Beane, S.  R. [Univ. of Washington, Seattle, WA (United States); Chang, E. [Univ. of Washington, Seattle, WA (United States); Cohen, S.  D. [Univ. of Washington, Seattle, WA (United States); Detmold, W. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Lin, H. -W. [Univ. of Washington, Seattle, WA (United States); Orginos, K. [College of William and Mary, Williamsburg, VA (United States); Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Parreño, A. [Univ., de Barcelona, Marti Franques (Spain); Savage, M.  J. [Univ. of Washington, Seattle, WA (United States)

    2015-06-11

    Quarkonium-nucleus systems are composed of two interacting hadronic states without common valence quarks, which interact primarily through multi-gluon exchanges, realizing a color van der Waals force. We present lattice QCD calculations of the interactions of strange and charm quarkonia with light nuclei. Both the strangeonium-nucleus and charmonium-nucleus systems are found to be relatively deeply bound when the masses of the three light quarks are set equal to that of the physical strange quark. Extrapolation of these results to the physical light-quark masses suggests that the binding energy of charmonium to nuclear matter is B < 40 MeV.

  4. Modifications induced by low power microwaves in plant nucleus

    International Nuclear Information System (INIS)

    Young rye plantlets exposed to low power microwaves from the X-band appeared affected at the cell nucleus level for various exposure times ranging between 30 minutes and 12 hours. Cell division capacity, controlled by cell nucleus seemed to be stimulated when the exposure was carried out on germinated caryopsides. Total number of abnormal nucleus divisions was enhanced by microwave exposure. Seed germination was slightly inhibited after electromagnetic exposure. Thermal as well as nonthermal effects at the level of nucleic acid macromolecules bearing genetic information might be invoked for the interpretation of the observed modifications

  5. Medium effects in the nucleon- nucleus reaction cross-section

    International Nuclear Information System (INIS)

    The nucleon-nucleus reaction cross-section, σR , has been calculated using Gabblers multiple scattering theory in its optical limit, A medium modified nuclear phase shift function has been obtained for nucleon-nucleus scattering using a medium two body scattering amplitude. In the present calculations, the Coulomb modified Glauber model is used. Also different forms of Gaussian density distribution, for the target nucleus, are used. A comparison of medium modified calculations with the corresponding experimental data has shown that application of the medium effect in the total reaction cross- section plays an important role for low values of energy

  6. Analysis of the thematic content of review Nucleus

    International Nuclear Information System (INIS)

    A computer programme for performing standardized analysis of research areas and key concepts of nuclear science and technology under development at Cubaenergia is presented. Main components of the information processing system, as well as computational methods and modules for thematic content analysis of INIS Database record files are described. Results of thematic content analysis of review Nucleus from 1986 to 2005 are shown. Furthermore, results of demonstrative study Nucleus, Science, Technology and Society are also shown. The results provide new elements to asses the significance of the thematic content of review Nucleus in the context of innovation in interrelated multidisciplinary research areas

  7. Electromagnetic probes of a pure-glue initial state in nucleus-nucleus collisions at energies available at the CERN Large Hadron Collider

    Science.gov (United States)

    Vovchenko, V.; Karpenko, Iu. A.; Gorenstein, M. I.; Satarov, L. M.; Mishustin, I. N.; Kämpfer, B.; Stoecker, H.

    2016-08-01

    Partonic matter produced in the early stage of ultrarelativistic nucleus-nucleus collisions is assumed to be composed mainly of gluons, and quarks and antiquarks are produced at later times. To study the implications of such a scenario, the dynamical evolution of a chemically nonequilibrated system is described by ideal (2+1)-dimensional hydrodynamics with a time dependent (anti)quark fugacity. The equation of state interpolates linearly between the lattice data for the pure gluonic matter and the lattice data for the chemically equilibrated quark-gluon plasma. The spectra and elliptic flows of thermal dileptons and photons are calculated for central Pb+Pb collisions at the CERN Large Hadron Collider energy of √{sN N}=2.76 TeV. We test the sensitivity of the results to the choice of equilibration time, including also the case where the complete chemical equilibrium of partons is reached already at the initial stage. It is shown that a suppression of quarks at early times leads to a significant reduction of the yield of the thermal dileptons, but only to a rather modest suppression of the pT distribution of direct photons. It is demonstrated that an enhancement of photon and dilepton elliptic flows might serve as a promising signature of the pure-glue initial state.

  8. Semiclassical model for single-particle transitions in nucleus-nucleus interactions

    International Nuclear Information System (INIS)

    A previously elaborated semiclassical one-body model for the dynamics of a single particle, moving in two potentials, in heavy-ion reactions or in fissioning systems has been extended with respect to the inclusion of angular momenta and more realistic separable potentials. The collective relative motion is assumed to proceed along a trajectory which is calculated from classical equations of motion including conservative and phenomenological friction forces. The formalism has been derived involving three-dimensional trajectories for symmetric as well as for asymmetric nucleus-nucleus systems. The model allows for the calculation of correct quantum mechanical transition amplitudes to final bound and continuum states. It has been applied for the investigation of the excitation of a neutron during a fission process, covering also non-statistical differential emission probabilities. From the numerical calculations, using parameters adapted to 252Cf(sf), one can conclude that in the underlying model without 'sudden' processes the energy spectrum consists of two parts. The low lying component is created in the neck region while a high lying part seems to be governed mainly by the dynamics of the underlying collective motion rather than by the specific initial conditions. (orig.)

  9. Multiparticle excitations in the 149 Gd superdeformed nucleus. Signature of new C4 nucleus symmetry

    International Nuclear Information System (INIS)

    The use of 8 π and EUROGAM phase I multi-detectors for the study of high spin states of 149 Gd nucleus has revealed unexpected new phenomenons about the superdeformation in this nucleus. The new excited bands confirm the omnipresence of twin bands phenomenon. A new multi-particle excitation (two protons and one neutron) has been discovered. Thanks to the second generation EUROGAM detector, unexpected discoveries such as C4 symmetry, level interactions, complete backbending were obtained for the second potential well. The knowledge of interacting levels gives informations about the nucleon-nucleon residual interaction and could allow the determination of SD bands excitation energy. The complex processing and analysis of high multiplicity events has led to the development of new computing tools. An automatic band research program has been written for the discovery of new excited bands, and an exact method for the elimination of uncorrected events has been developed. The improvements of multi-detector performances should allow the discovery of more exceptional phenomenons and new anomalies in the SD bands. (J.S.). 222 refs., 86 figs., 38 tabs

  10. Transparency and abrasion in high-energy nucleus-nucleus collisions

    International Nuclear Information System (INIS)

    The soft spheres geometric model of nucleus-nucleus collisions has been used to incorporate a tapered nuclear density distribution into considerations of transparency and of the abrasion step of the (hard spheres) abrasion-ablation model. The useful concept of an average target transparency tr > required a careful definition to accommodate the fact the transparency becomes unity as the impact parameter approaches infinity. The result is a simple numerical and calculation that gives tr > as a function of the soft spheres parameter χ. The latter depends in a known way on the target and projectile dimensions and on the energy-dependent nucleon-nucleon cross section. In the specific case of projectile = target, the result is an analytical expression reminiscent of the Fernbach, Serber and Taylor result for hard spheres. tr > = 1 - e-χ(χ+1)/χ2. Applications are expected to be valid for any projectile-target combination at intermediate (several hundred MeV/A) through ultrarelativistic (several hundred EeV/A) energies

  11. Relativistic transport approach for nucleus-nucleus collisions based on a NJL lagrangian

    CERN Document Server

    Ehehalt, W; Ehehalt, Wolfgang; Cassing, Wolfgang

    1995-01-01

    We formulate a covariant transport approach for high energy nucleus-nucleus collisions where the real part of the hadron selfenergies is evaluated on the basis of a NJL-type Lagrangian for the quark degrees of freedom. The parameters of the model Lagrangian are fixed by the Gell-Mann, Oakes and Renner relation, the pion-nucleon \\Sigma-term, the nucleon energy as well as the nuclear binding energy at saturation density \\rho_0. We find the resulting scalar and vector selfenergies for nucleons to be well in line with either Dirac-Brueckner results or those from the phenomenological optical potential when accounting for a swelling of the nucleon at finite nuclear matter density. The imaginary part of the hadron selfenergies is determined by a string fragmentation model which accounts for the in-medium mass of hadrons in line with the chiral dynamics employed. The applicability of the 'chiral' transport approach is demonstrated in comparison with experimental data from SIS to SPS energies. The enhancement of the K...

  12. Nuclear mean field and double-folding model of the nucleus-nucleus optical potential

    CERN Document Server

    Khoa, Dao T; Loan, Doan Thi; Loc, Bui Minh

    2016-01-01

    Realistic density dependent CDM3Yn versions of the M3Y interaction have been used in an extended Hartree-Fock (HF) calculation of nuclear matter (NM), with the nucleon single-particle potential determined from the total NM energy based on the Hugenholtz-van Hove theorem that gives rise naturally to a rearrangement term (RT). Using the RT of the single-nucleon potential obtained exactly at different NM densities, the density- and energy dependence of the CDM3Yn interactions was modified to account properly for both the RT and observed energy dependence of the nucleon optical potential. Based on a local density approximation, the double-folding model of the nucleus-nucleus optical potential has been extended to take into account consistently the rearrangement effect and energy dependence of the nuclear mean-field potential, using the modified CDM3Yn interactions. The extended double-folding model was applied to study the elastic $^{12}$C+$^{12}$C and $^{16}$O+$^{12}$C scattering at the refractive energies, wher...

  13. Energy-Dependence of Nucleus-Nucleus Potential and Friction Parameter in Fusion Reactions

    CERN Document Server

    Wen, Kai; Li, Zhu-Xia; Wu, Xi-Zhen; Zhang, Ying-Xun; Zhou, Shan-Gui

    2014-01-01

    Applying a macroscopic reduction procedure on the improved quantum molecular dynamics (ImQMD), the energy dependences of the nucleus-nucleus potential, the friction parameter, and the random force characterizing a one-dimensional Langevin-type description of the heavy-ion fusion process are investigated. Systematic calculations with the ImQMD show that the fluctuation-dissipation relation found in the symmetric head-on fusion reactions at energies just above the Coulomb barrier fades out when the incident energy increases. It turns out that this dynamical change with increasing incident energy is caused by a specific behavior of the friction parameter which directly depends on the microscopic dynamical process, i.e., on how the collective energy of the relative motion is transferred into the intrinsic excitation energy. It is shown microscopically that the energy dissipation in the fusion process is governed by two mechanisms: One is caused by the nucleon exchanges between two fusing nuclei, and the other is ...

  14. Nucleus--nucleus interactions in the inner crust of neutron stars

    CERN Document Server

    Kobyakov, D

    2016-01-01

    The interaction between nuclei in the inner crust of neutron stars consists of two contributions, the so-called "direct" interaction and an "induced" one due to density changes in the neutron fluid. For large nuclear separations $r$ the contributions from nuclear forces to each of these terms are shown to be nonzero. In the static limit they are equal in magnitude but have opposite signs and they cancel exactly. We analyze earlier results on effective interactions in the light of this finding. We consider the properties of long-wavelength collective modes and, in particular, calculate the degree of mixing between the lattice phonons and the phonons in the neutron superfluid. Using microscopic theory, we calculate the net non-Coulombic contribution to the nucleus--nucleus interaction and show that, for large $r$, the leading term is due to exchange of two phonons and varies as $1/r^7$: it is an analog of the Casimir--Polder interaction between neutral atoms.

  15. Estimation of nuclear destruction in high energy nucleus-nucleus interactions

    International Nuclear Information System (INIS)

    It is assumed that: 1) a projectile particle invokes into target nucleus a cascade of quark-gluon exchanges; 2) the nucleons involved in the cascade are ejected from the nucleus which leads to the nuclear destruction. On these bases a simple model to estimate the nuclear destruction at the fast stage of the interaction is proposed. The allowed region of the model parameters is determined at the proton-emulsion high-energy interaction data analysis: an analysis of gold interactions with nuclei at an energy of 600 MeV/nucleon fixes the parameter values. The distributions on the energy in zero degree calorimeter (TZDC) in the interactions of Si+Al, Cu, Pb (14 GeV/nucleon) and Au+Au (10 GeV/nucleon) calculated in the framework of the model and in the cascade-evaporation model (CEM) are presented. The proposed model describes the nuclear destruction at intermediate and high energies better than CEM does. The estimation of the average values of impact parameter and the number of intra-nuclear collisions for Au+Au interactions in the events with different TZDC is given. 34 refs., 11 figs

  16. Thermalization in high energy proton-nucleus collisions

    International Nuclear Information System (INIS)

    A relativistic proton-nucleus collision using the intranuclear cascade model is studied. The purpose is to verify the equilibration hypothesis at fragmentation time made by many nuclear fragmentation models. (author)

  17. Red nucleus connectivity as revealed by constrained spherical deconvolution tractography.

    Science.gov (United States)

    Milardi, Demetrio; Cacciola, Alberto; Cutroneo, Giuseppina; Marino, Silvia; Irrera, Mariangela; Cacciola, Giorgio; Santoro, Giuseppe; Ciolli, Pietro; Anastasi, Giuseppe; Calabrò, Rocco Salvatore; Quartarone, Angelo

    2016-07-28

    Previous Diffusion Tensor Imaging studies have demonstrated that the human red nucleus is widely interconnected with sensory-motor and prefrontal cortices. In this study, we assessed red nucleus connectivity by using a multi-tensor model called non- negative Constrained Spherical Deconvolution (CSD), which is able to resolve more than one fiber orientation per voxel. Connections of the red nuclei of fifteen volunteers were studied at 3T using CSD axonal tracking. We found significant connectivity between RN and the following cortical and subcortical areas: cerebellar cortex, thalamus, paracentral lobule, postcentral gyrus, precentral gyrus, superior frontal gyrus and dentate nucleus. We confirmed that red nucleus is tightly linked with the cerebral cortex and has dense subcortical connections with thalamus and cerebellar cortex. These findings may be useful in a clinical context considering that RN is involved in motor control and it is known to have potential to compensate for injury of the corticospinal tract. PMID:27181514

  18. Isotope Dependence of Superheavy Nucleus Formation Cross Section

    Institute of Scientific and Technical Information of China (English)

    LIU Zu-Hua; BAG Jing-Dong

    2006-01-01

    The dynamical process in the superheavy nucleus synthesis is studied on the basis of the two-dimensional Smolu-chowski equation. Special attention is paid to the isotope dependence of the cross section for the superheavy nucleus formation by means of making a comparison among the reaction systems of 54Fe + 204Pb, 56Fe + 206Pb, and 58Fe + 208Pb. It is found by this comparison that the formation cross section is very sensitive to the conditional saddle-point height and the neutron separation energy of the compound nucleus. Reaction systems with lower height of conditional saddle-point and smaller neutron separation energy are more favourable for the synthesis of the superheavy nucleus.

  19. Low-Energy Antinucleon-Nucleus Interaction Revisited

    CERN Document Server

    Friedman, E

    2015-01-01

    Annihilation cross sections of antiprotons and antineutrons on the proton between 50 and 400 MeV/c show Coulomb focusing below 200 MeV/c and almost no charge-dependence above 200 MeV/c. Similar comparisons for heavier targets are not possible for lack of overlap between nuclear targets studied with $\\bar p$ and $\\bar n$ beams. Interpolating between $\\bar p$-nucleus annihilation cross sections with the help of an optical potential to compare with $\\bar n$-nucleus annihilation cross sections reveal unexpected features of Coulomb interactions in the latter. Direct comparisons between $\\bar n$-nucleus and $\\bar p$-nucleus annihilations at very low energies could be possible if $\\bar p$ cross sections are measured on the same targets and at the same energies as the available cross sections for $\\bar n$. Such measurements may be feasible in the foreseeable future.

  20. Microscopic relativistic model for deuteron-nucleus scattering

    International Nuclear Information System (INIS)

    The relativistic deuteron structure described by the Bethe-Salpeter formalism is used to obtain the deuteron-nucleus interaction from the covariant convolution of Dirac-phenomenology nucleon-nucleus potentials. Multiple scattering contributions to deuteron-nucleus scattering are taken into account by the positive energy subtracted impulse approximation which results from an analysis of the role played by the relativistic degrees of freedom. A detailed comparison of calculations with deuteron-nucleus elastic scattering data at intermediate energies, including polarization observables, is presented. It is shown that good agreement with the data is obtained when the full spin structure of the interaction that results from the relativistic model is included in the calculations. copyright 1996 The American Physical Society

  1. Nucleus management in manual small incision cataract surgery by phacosection

    Directory of Open Access Journals (Sweden)

    Ravindra M

    2009-01-01

    Full Text Available Nucleus management is critical in manual small incision cataract surgery (MSICS, as the integrity of the tunnel, endothelium and posterior capsule needs to be respected. Several techniques of nucleus management are in vogue, depending upon the specific technique of MSICS. Nucleus can be removed in toto or bisected or trisected into smaller segments. The pressure in the eye can be maintained at the desired level with the use of an anterior chamber maintainer or kept at atmospheric levels. In MSICS, unlike phacoemulsification, there is no need to limit the size of the tunnel or restrain the size of capsulorrhexis. Large well-structured tunnels and larger capsulorrhexis provide better control on the surgical maneuvers. Safety and simplicity of MSICS has made it extremely popular. The purpose of this article is to describe nucleus management by phacosection in MSICS.

  2. Asymptotic properties of high-pT particle production in hadron-hadron, hadron-nucleus and nucleus-nucleus collisions at high energies

    CERN Document Server

    Tokarev, M V

    2001-01-01

    The concept of z-scaling reflecting the general features of particle substructure, constituent interaction and mechanism of particle formation is reviewed. Experimental data on the cross sections obtained at ISR, SpS and Tevatron are used in the analysis. The properties of data z-presentation, the energy and angular independencies, the power law, A- and F-dependencies, are discussed. The use of z-scaling to search for new physics phenomena in hadron-hadron, hadron-nucleus and nucleus-nucleus collisions is suggested. The violation of z-scaling characterized by the change of the fractal dimension is considered as a new and complimentary signature of nuclear phase transition.

  3. The Nucleus and Coma of Comet 67P/C-G at Millimeter and Submillimeter Wavelengths as seen by MIRO

    Science.gov (United States)

    Hofstadter, M. D.; Gulkis, S.; Allen, M.; Von Allmen, P.; Beaudin, G.; Biver, N.; Bockelée-Morvan, D.; Choukroun, M.; Crovisier, J.; Encrenaz, P.; Encrenaz, T.; Frerking, M. A.; Hartogh, P.; Ip, W. H.; Janssen, M. A.; Jarchow, C.; Keihm, S. J.; Lee, S.; Lellouch, E.; Leyrat, C.; Rezac, L.; Schloerb, F. P.; Spilker, T. R.

    2015-12-01

    The Microwave Instrument on the Rosetta Orbiter (MIRO) makes submillimeter- and millimeter-wavelength observations of Comet 67P/Churyumov-Gerasimenko. Broadband continuum measurements at wavelengths of 0.5 and 1.6 mm probe the thermal and dielectric properties of the nucleus subsurface. High-resolution spectroscopic measurements of 8 molecular lines in the submillimeter (H2O, H217O, H218O, CO, NH3, and three lines of CH3OH) constrain the abundance, velocity, and temperature of gases in the coma. These measurements allow MIRO to study the nucleus and coma as a coupled system. Using its two continuum channels, MIRO has mapped the thermal properties of the nucleus subsurface (depths from millimeters to tens of centimeters), and generally finds its properties to be consistent with very porous, dusty material. We see temperature variations due to diurnal and seasonal changes in insolation, and also see evidence for subsurface ice in some regions. This talk will provide an update on our observations of variations over time, variations with temperature, and variations in composition. We also will report on our attempts to detect the continuum thermal emission of dust in the coma. MIRO's spectroscopic observations have shown the abundance and velocity of gas as it comes off the nucleus to vary with time and location. The regions MIRO sees as particularly active are generally consistent with activity reported by other instruments. Moving away from the nucleus, MIRO is sensitive to the three-dimensional structure of the coma. We will present an update on our understanding of that structure, which is influenced by the shape of the nucleus, nucleus rotation, and processes acting within and on the coma. Our ultimate goal is to develop a coupled model of the nucleus and coma, tracing the processes by which solar heating of the surface drives sublimation of subsurface ice and generation of dust, and how gases and dust evolve in the coma. Part of this work was conducted at the Jet

  4. Specific structure of the 6He nucleus and fragmentation experiments

    International Nuclear Information System (INIS)

    Within the framework of the microscopic α+2n model, transverse momentum distributions of α-particles and neutrons as well as α-particle - neutron momentum correlation function have been calculated for the radioactive 6He nucleus fragmentation. The results show that these momentum distributions reflect a specific structure of the 6He nucleus, i.e. the experiments on fragmentation provide with the information on 6He structure. (orig.)

  5. Nucleus Pearl Coating Process of Freshwater Mussel Anodonta woodiana (Unionidae)

    OpenAIRE

    WASMEN MANALU; DEDY DURYADI SOLIHIN; SATA YOSHIDA SRIE RAHAYU; RIDWAN AFFANDI

    2013-01-01

    The limiting factor which is a weakness of sea water pearl production are high costs, the risk of major business failures and a long coating time. From the issue of freshwater pearls appear to have prospects of alternative substitution for sea water pearl. This present study aimed to evaluate effect of loads (the number and diameter nucleus) on freshwater pearl coating process and the number and size of the appropriate nucleus diameter, to produce the optimum coating thickness of half-round p...

  6. Limbic and cortical information processing in the nucleus accumbens

    OpenAIRE

    Goto, Yukiori; Grace, Anthony A.

    2008-01-01

    The nucleus accumbens regulates goal-directed behaviors by integrating information from limbic structures and the prefrontal cortex. Here, we review recent studies in an attempt to provide an integrated view of the control of information processing in the nucleus accumbens in terms of the regulation of goal-directed behaviors and how disruption of these functions might underlie the pathological states in drug addiction and other psychiatric disorders. We propose a model that could account for...

  7. Vacuum polarization and quadrupole moment of a heavy nucleus

    International Nuclear Information System (INIS)

    The contribution of the vacuum polarization to the quadrupole moment of a heavy nucleus is considered. The leading term is obtained exactly in Zα, using the electron Green function in the Coulomb field. This term contains the large logarithm of the ratio λ/R, where R is the nucleus radius and λ is the electron Compton wavelength. The spatial distributions of the induced charge and potential are discussed also. 9 refs.; 1 fig

  8. Ion-beam spectroscopic studies of the 69As nucleus

    International Nuclear Information System (INIS)

    Excited state of the neutron deficient 69As nucleus were investigated in the 58Ni(14N,2pn) reaction by ion-beam γ spectroscopic methods (excitation functions, γγ-coincidences, angular distributions and linear polarization gated with neutrons). A new more complete level scheme of 69As has been proposed with spin-parity values. The structure of the nucleus is discussed in the framework of the interaction boson-fermion model (IBFM). (authors)

  9. New computational methods for determining antikaon-nucleus bound states

    International Nuclear Information System (INIS)

    Optical potential for antikaon-nucleus strong interactions are constructed using elementary antikaon-nucleus potentials determined previously. The optical potentials are used to determine the existence of a kaon hypernucleus. Modern three dimensional visualization techniques are used to study model dependences, new methods for speeding the calculation of the optical potential are developed, and previous approximation to avoid full Fermi averaging are eliminated. 19 refs., 21 figs., 3 tabs

  10. Inelaticity in hadron-nucleus collisions from emulsion chamber studies

    CERN Document Server

    Wilk, G

    1999-01-01

    The inelasticity of hadron-carbon nucleus collisions in the energy region exceeding 100 TeV is estimated from the carbon-emulsion chamber data at Pamirs to be $ = 0.65\\pm 0.08$. When combined with the recently presented data on hadron-lead nucleus collisions taken at the same energy range it results in the $K\\sim A^{0.086}$ mass number dependence of inelasticity. The evaluated partial inelasticity for secondary ($\

  11. Shell Correction at the Saddle Point for Superheavy Nucleus

    Institute of Scientific and Technical Information of China (English)

    张炜; 张时声; 张双全; 孟杰

    2003-01-01

    The potential energy surface for superheavy nucleus has been studied within the framework of the constrained relativistic mean field theory, and the shell correction energy as a function of deformation has been extracted by the Strutinsky shell correction procedure. Contrary to the usual expectation, the shell correction energy at the saddle point is too important to be neglected, and it has essential contribution to the fission barrier in superheavy nucleus.

  12. Impact of overactive bladder on the brain: Central sequelae of a visceral pathology

    OpenAIRE

    Rickenbacher, Elizabeth; Baez, Madelyn A.; Hale, Lyman; Leiser, Steven C; Zderic, Stephen A.; Valentino, Rita J.

    2008-01-01

    Neural circuits that allow for reciprocal communication between the brain and viscera are critical for coordinating behavior with visceral activity. At the same time, these circuits are positioned to convey signals from pathologic events occurring in viscera to the brain, thereby providing a structural basis for comorbid central and peripheral symptoms. In the pons, Barrington's nucleus and the norepinephrine (NE) nucleus, locus coeruleus (LC), are integral to a circuit that links the pelvic ...

  13. Childhood physical abuse predicts stressor-evoked activity within central visceral control regions

    OpenAIRE

    Banihashemi, Layla; Sheu, Lei K.; Midei, Aimee J.; Gianaros, Peter J.

    2014-01-01

    Early life experience differentially shapes later stress reactivity, as evidenced by both animal and human studies. However, early experience-related changes in the function of central visceral neural circuits that control stress responses have not been well characterized, particularly in humans. The paraventricular nucleus of the hypothalamus (PVN), bed nucleus of the stria terminalis (BNST), amygdala (Amyg) and subgenual anterior cingulate cortex (sgACC) form a core visceral stress-responsi...

  14. Variable stars and stellar populations in Andromeda XXV: III. A central cluster or the galaxy nucleus?

    CERN Document Server

    Cusano, Felice; Clementini, Gisella; Cignoni, Michele; Federici, Luciana; Marconi, Marcella; Ripepi, Vincenzo; Musella, Ilaria; Testa, Vincenzo; Carini, Roberta; Faccini, Marco

    2016-01-01

    We present B and V time-series photometry of Andromeda XXV, the third galaxy in our program on the Andromeda's satellites, that we have imaged with the Large Binocular Cameras of the Large Binocular Telescope. The field of Andromeda XXV is found to contain 63 variable stars, for which we present light curves and characteristics of the light variation (period, amplitudes, variability type, mean magnitudes, etc.). The sample includes 58 RR Lyrae variables (46 fundamental-mode $-$ RRab, and 12 first-overtone $-$RRc, pulsators), three anomalous Cepheids, one eclipsing binary system and one unclassified variable. The average period of the RRab stars ($\\langle Pab \\rangle$ = 0.60 $\\sigma=0.04$ days) and the period-amplitude diagram place Andromeda XXV in the class of the Oosterhoff-Intermediate objects. From the average luminosity of the RR Lyrae stars we derive for the galaxy a distance modulus of (m-M)$_0$=$24.63\\pm0.17$ mag. The color-magnitude diagram reveals the presence in Andromeda XXV of a single, metal-poo...

  15. A Universal Description of Pseudorapidity Distributions in Both Nucleus-Nucleus and p-p Collisions at Currently Available Energies

    Directory of Open Access Journals (Sweden)

    Z. J. Jiang

    2016-01-01

    Full Text Available Investigations have shown that the collective motion appears not only in nucleus-nucleus but also in p-p collisions. The best tool for depicting such collective motion is relativistic hydrodynamics. In this paper, the collective motion is assumed to obey the hydrodynamic model which integrates the features of Landau and Hwa-Bjorken theory and is one of a very few analytically solvable models. The fluid is then supposed to freeze out into charged particles from a space-like hypersurface with a fixed time of tFO. The investigations of present paper show that this part of charged particles together with leading particles, which, by conventional definition, carry on the quantum numbers of colliding nucleons and take away the most part of incident energy, can give a proper universal description to the pseudorapidity distributions of charged particles measured in both nucleus-nucleus and p-p collisions at currently available energies.

  16. Roles for pituitary adenylate cyclase-activating peptide (PACAP) expression and signaling in the bed nucleus of the stria terminalis (BNST) in mediating the behavioral consequences of chronic stress

    OpenAIRE

    Hammack, Sayamwong E.; Roman, Carolyn W.; Lezak, Kimberly R.; Kocho-Shellenberg, Margaret; Grimmig, Bethany; Falls, William A; Braas, Karen; May, Victor

    2010-01-01

    Anxiety disorders are frequently long-lasting and debilitating for more than 40 million American adults. Although stressor exposure plays an important role in the etiology of some anxiety disorders, the mechanisms by which exposure to stressful stimuli alters central circuits that mediate anxiety-like emotional behavior are still unknown. Substantial evidence has implicated regions of the central extended amygdala, including the bed nucleus of the stria terminalis (BNST) and the central nucle...

  17. The picture of the nuclei disintegration mechanism - from nucleus-nucleus collision experimental data at high energies

    International Nuclear Information System (INIS)

    Experimental data on nuclear collisions at high energies, mainly obtained from photographic emulsions, are considered from the point of view of the picture of the nuclear collision processes mechanisms prompted experimentally. In fact, the disintegration products of each nucleus involved in a nuclear collision, in its own rest-frame, are similar to that produced by the impact of a number of nucleons of velocity equal to that of the moving primary nucleus

  18. Modulation of the arcuate nucleus-medial preoptic nucleus lordosis regulating circuit: a role for GABAB receptors

    OpenAIRE

    Sinchak, Kevin; Dewing, Phoebe; Ponce, Laura; Gomez, Liliana; Christensen, Amy; Berger, Max; Micevych, Paul

    2013-01-01

    Estradiol rapidly activates a microcircuit in the arcuate nucleus of the hypothalamus (ARH) that is needed for maximal female sexual receptivity. Membrane estrogen receptor-α complexes with and signals through the metabotropic glutamate receptor-1a stimulating NPY release within the ARH activating proopiomelanocortin (POMC) neurons. These POMC neurons project to the medial preoptic nucleus (MPN) and release β-endorphin. Estradiol treatment induces activation/internalization of MPN μ-opioid re...

  19. ELECTROPHYSIOLOGICAL PROPERTIES OF MORPHOLOGICALLY-IDENTIFIED MEDIAL VESTIBULAR NUCLEUS NEURONS PROJECTING TO THE ABDUCENS NUCLEUS IN THE CHICK EMBRYO

    OpenAIRE

    Gottesman-Davis, Adria; Shao, Mei; Hirsch, June C.; Peusner, Kenna D.

    2010-01-01

    Neurons in the medial vestibular nucleus (MVN) show a wide range of axonal projection pathways, intrinsic firing properties, and responses to head movements. To determine whether MVN neurons participating in the vestibulocular reflexes (VOR) have distinctive electrophysiological properties related to their output pathways, a new preparation was devised using transverse brain slices containing the chicken MVN and abducens nucleus. Biocytin Alexa Fluor was injected extracellularly into the abdu...

  20. Strange particles production in relativistic nucleus-nucleus collisions at the RHIC BES energy region

    CERN Document Server

    Zhang, Cong-Cong; Feng, Sheng-Qin; Yin, Zhong-Bao

    2015-01-01

    The parton and hadron cascade model PACIAE is utilized to investigate strange particle productions in Au + Au collision at $\\sqrt{s}$=62.4 GeV in different centralities and at $\\sqrt{s}$= 39, 11.5 and 7.7 GeV in the most central collision, respectively. It is shown that the transverse momentum distributions of strange particles by the PACIAE model fit well the RHIC BES experimental results.

  1. On the Role of the Transition State Nucleus in Fission

    International Nuclear Information System (INIS)

    Although it is well-known that times. In order for fission to compete favourably with gamma-ray and neutron emission, a fixed amount of energy, equivalent to an activation energy in a chemical reaction, must be supplied to the heavy nucleus. This energy (often referred to as the fission threshold) is approximately 5 to 6 MeV for U238, and is the minimum energy required to produce the deformed transition state nucleus (zero internal excitation energy). In the process of stretching the original nucleus into the transition state nucleus (whose distortion is sometimes described as the saddle-point deformation), the increase in energy due to the short-range nuclear forces (surface tension) is greater than the decrease in energy due to the long-range Coulomb forces. However, as the particular distortion defining the transition state nucleus is approached, the decrease in Coulomb energy becomes equal to the increase in surface energy. The degree of distortion needed to produce the transition state nucleus is a function of several nuclear parameters and, hence, the saddle shape and threshold energy for fission change markedly for different nuclei. Since a large fraction of the excitation energy of the initial compound nucleus is consumed in deformation energy in passing to the fission saddle point, the transition state nucleus is thermodynamically ''cold''. Hence, for low excitation energies where the non-fission degrees of freedom favour the passage of the barrier with only a small kinetic energy, it seems reasonable to postulate that the traversal time of the saddle or the lifetime of the transition state nucleus is many orders of magnitude longer than the characteristic nuclear time. This leads to the prediction that the highly deformed transition state nucleus will have properties, including a spectrum of excited states, analogous to those of normal nuclei. Information on highly deformed transition state nuclei obtained by fission-fragment angular distribution studies

  2. The deafferented reticular thalamic nucleus generates spindle rhythmicity.

    Science.gov (United States)

    Steriade, M; Domich, L; Oakson, G; Deschênes, M

    1987-01-01

    The hypothesis that nucleus reticularis thalami (RE) is the generator of spindle rhythmicity during electroencephalogram (EEG) synchronization was tested in acutely prepared cats. Unit discharges and focal waves were extracellularly recorded in the rostral pole of RE nucleus, which was completely disconnected by transections from all other thalamic nuclei. In some experiments, additional transections through corona radiata created a triangular island in which the rostral RE pole survived with the caudate nucleus, putamen, basal forebrain nuclei, prepyriform area, and the adjacent cortex. Similar results were obtained in two types of experiments: brain stem-transected preparations that exhibited spontaneous spindle sequences, and animals under ketamine anesthesia in which transient spindling was repeatedly precipitated during recording by very low doses of a short-acting barbiturate. Both spindle-related rhythms (7- to 16-Hz waves grouped in sequences that recur with a rhythm of 0.1-0.3 Hz) are seen in focal recordings of the deafferented RE nucleus. The presence of spindling rhythmicity in the disconnected RE nucleus contrasts with total absence of spindles in cortical EEG leads and in thalamic recordings behind the transection. Oscillations within the same frequency range as that of spontaneous spindles can be evoked in the deafferented RE nucleus by subcortical white matter stimulation. In deafferented RE cells, the burst structure consists of an initially biphasic acceleration-deceleration pattern, eventually leading to a long-lasting tonic tail. Quantitative group data show that the burst parameters of disconnected RE cells are very similar to those of RE neurons with intact connections. In the deafferented RE nucleus, spike bursts of RE neurons recur periodically (0.1-0.3 Hz) in close time-relation with simultaneously recorded focal spindle sequences. The burst occurrence of deafferented RE cells is greatly reduced after systemic administration of bicuculline

  3. ICC模型对英语专业学生跨文化交际能力培养的启示%Enlightenment of ICC model for English major students' cross-cultural communication ability training

    Institute of Scientific and Technical Information of China (English)

    周虹

    2015-01-01

    应用型高校英语专业以职业能力为本位,注重学生独立思考、分析问题和跨文化交际能力的培养。跨文化交际(ICC)理论模型包含的四个要素,态度、知识、技能和文化批评意识,对以《英语国家概况》为代表的一些英语专业课程的教学和跨文化交际能力的培养具有积极的启示和指导作用。培养学生的跨文化意识和交际的能力,需要为学生提供一个模拟的多元文化环境,帮助他们构建起自身的文化身份,鼓励学生在持有开放态度的前提下,接收信息、比较异同、分析问题、评判文化。%Applied university English majors in vocational ability as the standard, pay attention to students' independent thinking, analyzing and the cultivation of intercultural communicative competence. The ICC model includes four elements: knowledge, skills, and attitudes and cultural criticism consciousness, has a positive role in revelation and guiding role on English major teaching and the cultivation of intercultural communicative competence that represented by the English country profiles. Develop the students' cross-cultural awareness and ability of communication, need a simulation of the multicultural environment, help them build up their own cultural identity, encourage students to hold open under the premise of receiving information, compare, analyze and judge the cultural similarities and differences.

  4. ICC '86; Proceedings of the International Conference on Communications, Toronto, Canada, June 22-25, 1986, Conference Record. Volumes 1, 2, & 3

    Science.gov (United States)

    Papers are presented on ISDN, mobile radio systems and techniques for digital connectivity, centralized and distributed algorithms in computer networks, communications networks, quality assurance and impact on cost, adaptive filters in communications, the spread spectrum, signal processing, video communication techniques, and digital satellite services. Topics discussed include performance evaluation issues for integrated protocols, packet network operations, the computer network theory and multiple-access, microwave single sideband systems, switching architectures, fiber optic systems, wireless local communications, modulation, coding, and synchronization, remote switching, software quality, transmission, and expert systems in network operations. Consideration is given to wide area networks, image and speech processing, office communications application protocols, multimedia systems, customer-controlled network operations, digital radio systems, channel modeling and signal processing in digital communications, earth station/on-board modems, computer communications system performance evaluation, source encoding, compression, and quantization, and adaptive communications systems.

  5. PREFACE: 11th International Conference on Nucleus-Nucleus Collisions (NN2012)

    Science.gov (United States)

    Li, Bao-An; Natowitz, Joseph B.

    2013-03-01

    The 11th International Conference on Nucleus-Nucleus Collisions (NN2012) was held from 27 May to 1 June 2012, in San Antonio, Texas, USA. It was jointly organized and hosted by The Cyclotron Institute at Texas A&M University, College Station and The Department of Physics and Astronomy at Texas A&M University-Commerce. Among the approximately 300 participants were a large number of graduate students and post-doctoral fellows. The Keynote Talk of the conference, 'The State of Affairs of Present and Future Nucleus-Nucleus Collision Science', was given by Dr Robert Tribble, University Distinguished Professor and Director of the TAMU Cyclotron Institute. During the conference a very well-received public lecture on neutrino astronomy, 'The ICEcube project', was given by Dr Francis Halzen, Hilldale and Gregory Breit Distinguished Professor at the University of Wisconsin, Madison. The Scientific program continued in the general spirit and intention of this conference series. As is typical of this conference a broad range of topics including fundamental areas of nuclear dynamics, structure, and applications were addressed in 42 plenary session talks, 150 parallel session talks, and 21 posters. The high quality of the work presented emphasized the vitality and relevance of the subject matter of this conference. Following the tradition, the NN2012 International Advisory Committee selected the host and site of the next conference in this series. The 12th International Conference on Nucleus-Nucleus Collisions (NN2015) will be held 21-26 June 2015 in Catania, Italy. It will be hosted by The INFN, Laboratori Nazionali del Sud, INFN, Catania and the Dipartimento di Fisica e Astronomia of the University of Catania. The NN2012 Proceedings contains the conference program and 165 articles organized into the following 10 sections 1. Heavy and Superheavy Elements 2. QCD and Hadron Physics 3. Relativistic Heavy-Ion Collisions 4. Nuclear Structure 5. Nuclear Energy and Applications of

  6. Nucleus Pearl Coating Process of Freshwater Mussel Anodonta woodiana (Unionidae

    Directory of Open Access Journals (Sweden)

    WASMEN MANALU

    2013-03-01

    Full Text Available The limiting factor which is a weakness of sea water pearl production are high costs, the risk of major business failures and a long coating time. From the issue of freshwater pearls appear to have prospects of alternative substitution for sea water pearl. This present study aimed to evaluate effect of loads (the number and diameter nucleus on freshwater pearl coating process and the number and size of the appropriate nucleus diameter, to produce the optimum coating thickness of half-round pearls. The research consists of experimental implantation of 2, 4, and 6 nucleus number per individual mussel was maintained by the method stocked in hapa in bottom waters. Observation method and factorial randomized block design used in the study of the influence of the load to the successfulness of pearl coating and the pearl layer thickness. The results showed that A. woodiana can be utilized as a producer of freshwater pearls. In addition, the number of optimum nucleus that can be attached to the mussel A. woodiana was 2 grains/individuals with a diameter of 10 mm. Shells implanted with the optimum nucleus diameter and number of pearls produced the highest layer thickness of 17 m after 9 months cultivation. This result was good enough compared with the layer thickness of sea water pearl production after the same cultivation time.

  7. The hadron-nucleus collision reaction mechanism memorized by fast nucleons emitted from target nuclei

    International Nuclear Information System (INIS)

    It is shown in this work that: 1. The target-nucleus damaged in a hadron-nucleus nuclear collision memorizes information about the collision mechanism; 2. Similar information is contained in characteristics of the incident hadron passage through the target nucleus. The mechanism of the hadron-nucleus collision process is presented - as experimentally based, from the collision reaction starting up to the destroyed target-nucleus transmutation into stable fragments. 34 refs., 2 figs

  8. Disrupted Leptin Signaling in the Lateral Hypothalamus and Ventral Premammillary Nucleus Alters Insulin and Glucagon Secretion and Protects Against Diet-Induced Obesity.

    Science.gov (United States)

    Denroche, Heather C; Glavas, Maria M; Tudurí, Eva; Karunakaran, Subashini; Quong, Whitney L; Philippe, Marion; Britton, Heidi M; Clee, Susanne M; Kieffer, Timothy J

    2016-07-01

    Leptin signaling in the central nervous system, and particularly the arcuate hypothalamic nucleus, is important for regulating energy and glucose homeostasis. However, the roles of extra-arcuate leptin responsive neurons are less defined. In the current study, we generated mice with widespread inactivation of the long leptin receptor isoform in the central nervous system via Synapsin promoter-driven Cre (Lepr(flox/flox) Syn-cre mice). Within the hypothalamus, leptin signaling was disrupted in the lateral hypothalamic area (LHA) and ventral premammillary nucleus (PMV) but remained intact in the arcuate hypothalamic nucleus and ventromedial hypothalamic nucleus, dorsomedial hypothalamic nucleus, and nucleus of the tractus solitarius. To investigate the role of LHA/PMV neuronal leptin signaling, we examined glucose and energy homeostasis in Lepr(flox/flox) Syn-cre mice and Lepr(flox/flox) littermates under basal and diet-induced obese conditions and tested the role of LHA/PMV neurons in leptin-mediated glucose lowering in streptozotocin-induced diabetes. Lepr(flox/flox) Syn-cre mice did not have altered body weight or blood glucose levels but were hyperinsulinemic and had enhanced glucagon secretion in response to experimental hypoglycemia. Surprisingly, when placed on a high-fat diet, Lepr(flox/flox) Syn-cre mice were protected from weight gain, glucose intolerance, and diet-induced hyperinsulinemia. Peripheral leptin administration lowered blood glucose in streptozotocin-induced diabetic Lepr(flox/flox) Syn-cre mice as effectively as in Lepr(flox/flox) littermate controls. Collectively these findings suggest that leptin signaling in LHA/PMV neurons is not critical for regulating glucose levels but has an indispensable role in the regulation of insulin and glucagon levels and, may promote the development of diet-induced hyperinsulinemia and weight gain. PMID:27183315

  9. Nitric oxide in the nucleus raphe magnus modulates cutaneous blood flow in rats during hypothermia

    Directory of Open Access Journals (Sweden)

    Masoumeh Kourosh Arami

    2015-10-01

    Full Text Available Objective(s: Nucleus Raphe Magnus (NRM that is involved in the regulation of body temperature contains nitric oxide (NO synthase. Considering the effect of NO on skin blood flow control, in this study, we assessed its thermoregulatory role within the raphe magnus. Materials and Methods: To this end, tail blood flow of male Wistar rats was measured by laser doppler following the induction of hypothermia. Results: Intra-NRM injection of SNP (exogenous NO donor, 0.1- 0.2 μl, 0.2 nM increased the blood flow. Similarly, unilateral microinjection of glutamate (0.1- 0.2 μl, 2.3 nM into the nucleus increased the blood flow. This effectof L-glutamate was reduced by prior intra NRM administrationof NO synthase inhibitor NG-methyl-L-arginine or NG-nitro-L-argininemethyl ester (L-NAME, 0.1 µl, 100 nM. Conclusion: It is concluded that NO modulates the thermoregulatory response of NRM to hypothermia and may interactwith excitatory amino acids in central skin blood flow regulation.

  10. Tolerance to non-opioid analgesics is opioid-sensitive in nucleus raphe magnus

    Directory of Open Access Journals (Sweden)

    MerabGTsagareli

    2011-07-01

    Full Text Available Repeated injection of opioid analgesics can lead to a progressive loss of its effect. This phenomenon is known as tolerance. Several lines of investigations have shown that systemic, intraperitoneal administration or the microinjection of non-opioid analgesics, non-steroidal anti-inflammatory drugs (NSAIDs in the midbrain periaqueductal gray matter induces antinociception with some effects of tolerance. Our recent study has revealed that microinjection of three drugs analgin, ketorolac and xefocam into the central nucleus of amygdala produce tolerance to them and cross-tolerance to morphine. Here we report that repeated administrations of these NSAIDs into the nucleus raphe magnus (NRM in the following four days result in progressively less antinociception, i.e. produce the development of tolerance to these drugs in mail rats. Special control experiments showed that post-treatment with μ-opioid antagonist naloxone in NRM significantly decreased antinociceptive effects of NSAIDs at the first day in behavioral tail flick reflex (TF and hot plate (HP latencies. At the second day, naloxone generally had trend effects in both TF and HP tests impeded the development of tolerance to the antinociceptive effect of non-opioid analgesics. These findings strongly support the suggestion on endogenous opioid involvement in NSAIDs antinociception and tolerance in the descending pain control system. Moreover, repeated injections of NSAIDs progressively lead to tolerance to them, cross-tolerance to morphine and the risk of a withdrawal syndrome. Therefore, these results are important for human medicine too.

  11. A MINOR MERGER CAUGHT IN THE ACT OF FUELING THE ACTIVE GALACTIC NUCLEUS IN Mrk 509

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, T. C.; Crenshaw, D. M. [Department of Physics and Astronomy, Georgia State University, Astronomy Offices, 25 Park Place, Suite 600, Atlanta, GA 30303 (United States); Kraemer, S. B. [Institute for Astrophysics and Computational Sciences, Department of Physics, The Catholic University of America, Washington, DC 20064 (United States); Schmitt, H. R. [Naval Research Laboratory, Washington, DC 20375 (United States); Storchi-Bergmann, T. [Departamento de Astronomia, Universidade Federal do Rio Grande do Sul, IF, CP 15051, 91501-970 Porto Alegre, RS (Brazil); Riffel, R. A., E-mail: fischer@astro.gsu.edu [Departamento de Física, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, 97105-900 Santa Maria, RS (Brazil)

    2015-02-01

    In recent observations by the Hubble Space Telescope (HST) as part of a campaign to discover locations and kinematics of AGN outflows, we found that Mrk 509 contains a 3'' (∼2100 pc) linear filament in its central region. Visible in both optical continuum and [O III] imaging, this feature resembles a ''check mark'' of several knots of emission that travel northwest to southeast before jutting toward the nucleus from the southwest. Space Telescope Imaging Spectrograph (STIS/HST) observations along the inner portion of the filament reveal redshifted velocities, indicating that the filament is inflowing. We present further observations of the nucleus in Mrk 509 using the Gemini Near-Infrared Integral Field Spectrograph, from which we conclude that this structure cannot be related to previously studied, typical narrow line region outflows and instead embodies the remains of an ongoing minor merger with a gas-rich dwarf galaxy, therefore providing a great opportunity to study the fueling of an AGN by a minor merger in progress.

  12. Optimal reactions for the synthesis of superheavy nucleus 270Hs

    Institute of Scientific and Technical Information of China (English)

    LIU Zuhua; BAO Jingdong

    2006-01-01

    The superheavy nucleus 270 Hs iS expected to be a "double-magic" deformed nucleus.We have calculated its cross sections of evaporation residue for the reactions 248Cm(26Mg,4n)270Hs,244pu(30Si,4n)270Hs,238U(36S,4n)270Hs and 226Ra(48Ca,4n)270Hs using a two-parameter Smoluchowski equation.It is found from our results that 226Ra(48Ca,4n)270Hs and 238U(36S,4n)270Hs are two optimal reactions for the synthesis of the superheavy nucleus 270Hs due to their large negative Q-values.

  13. Extreme alpha-clustering in the 18O nucleus

    CERN Document Server

    Johnson, E D; Goldberg, V Z; Brown, S; Robson, D; Crisp, A M; Cottle, P D; Fu, C; Giles, J; Green, B W; Kemper, K W; Lee, K; Roeder, B T; Tribble, R E

    2009-01-01

    The structure of the 18O nucleus at excitation energies above the alpha decay threshold was studied using 14C+alpha resonance elastic scattering. A number of states with large alpha reduced widths have been observed, indicating that the alpha-cluster degree of freedom plays an important role in this N not equal Z nucleus. However, the alpha-cluster structure of this nucleus is very different from the relatively simple pattern of strong alpha-cluster quasi-rotational bands in the neighboring 16O and 20Ne nuclei. A 0+ state with an alpha reduced width exceeding the single particle limit was identified at an excitation energy of 9.9+/-0.3 MeV. We discuss evidence that states of this kind are common in light nuclei and give possible explanations of this feature.

  14. Immobility, inheritance and plasticity of shape of the yeast nucleus

    Directory of Open Access Journals (Sweden)

    Andrulis Erik D

    2007-11-01

    Full Text Available Abstract Background Since S. cerevisiae undergoes closed mitosis, the nuclear envelope of the daughter nucleus is continuous with that of the maternal nucleus at anaphase. Nevertheless, several constitutents of the maternal nucleus are not present in the daughter nucleus. The present study aims to identify proteins which impact the shape of the yeast nucleus and to learn whether modifications of shape are passed on to the next mitotic generation. The Esc1p protein of S. cerevisiae localizes to the periphery of the nucleoplasm, can anchor chromatin, and has been implicated in targeted silencing both at telomeres and at HMR. Results Upon increased Esc1p expression, cell division continues and dramatic elaborations of the nuclear envelope extend into the cytoplasm. These "escapades" include nuclear pores and associate with the nucleolus, but exclude chromatin. Escapades are not inherited by daughter nuclei. This exclusion reflects their relative immobility, which we document in studies of prezygotes. Moreover, excess Esc1p affects the levels of multiple transcripts, not all of which originate at telomere-proximal loci. Unlike Esc1p and the colocalizing protein, Mlp1p, overexpression of selected proteins of the inner nuclear membrane is toxic. Conclusion Esc1p is the first non-membrane protein of the nuclear periphery which – like proteins of the nuclear lamina of higher eukaryotes – can modify the shape of the yeast nucleus. The elaborations of the nuclear envelope ("escapades" which appear upon induction of excess Esc1p are not inherited during mitotic growth. The lack of inheritance of such components could help sustain cell growth when parental nuclei have acquired potentially deleterious characteristics.

  15. Silk fibroin porous scaffolds for nucleus pulposus tissue engineering

    Energy Technology Data Exchange (ETDEWEB)

    Zeng, Chao; Yang, Qiang [Department of Spine Surgery, Tianjin Hospital, Tianjin 300211 (China); Tianjin Medical University, Tianjin 300070 (China); Zhu, Meifeng [The Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071 (China); Du, Lilong [Department of Spine Surgery, Tianjin Hospital, Tianjin 300211 (China); Tianjin Medical University, Tianjin 300070 (China); Zhang, Jiamin [The Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071 (China); Ma, Xinlong [Department of Spine Surgery, Tianjin Hospital, Tianjin 300211 (China); Xu, Baoshan, E-mail: xubaoshan99@126.com [Department of Spine Surgery, Tianjin Hospital, Tianjin 300211 (China); Wang, Lianyong, E-mail: wly@nankai.edu.cn [The Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071 (China)

    2014-04-01

    Intervertebral discs (IVDs) are structurally complex tissue that hold the vertebrae together and provide mobility to spine. The nucleus pulposus (NP) degeneration often results in degenerative IVD disease that is one of the most common causes of back and neck pain. Tissue engineered nucleus pulposus offers an alternative approach to regain the function of the degenerative IVD. The aim of this study is to determine the feasibility of porous silk fibroin (SF) scaffolds fabricated by paraffin-sphere-leaching methods with freeze-drying in the application of nucleus pulposus regeneration. The prepared scaffold possessed high porosity of 92.38 ± 5.12% and pore size of 165.00 ± 8.25 μm as well as high pore interconnectivity and appropriate mechanical properties. Rabbit NP cells were seeded and cultured on the SF scaffolds. Scanning electron microscopy, histology, biochemical assays and mechanical tests revealed that the porous scaffolds could provide an appropriate microstructure and environment to support adhesion, proliferation and infiltration of NP cells in vitro as well as the generation of extracellular matrix. The NP cell–scaffold construction could be preliminarily formed after subcutaneously implanted in a nude mice model. In conclusion, The SF porous scaffold offers a potential candidate for tissue engineered NP tissue. - Highlights: • Paraffin microsphere-leaching method is used to fabricate silk fibroin scaffold. • The scaffold has appropriate mechanical property, porosity and pore size • The scaffold supports growth and infiltration of nucleus pulposus cells. • Nucleus pulposus cells can secrete extracellular matrix in the scaffolds. • The scaffold is a potential candidate for tissue engineered nucleus pulposus.

  16. Social interaction and cocaine conditioning in mice increase spontaneous spike frequency in the nucleus accumbens or septal nuclei as revealed by multielectrode array recordings.

    Science.gov (United States)

    Kummer, Kai K; El Rawas, Rana; Kress, Michaela; Saria, Alois; Zernig, Gerald

    2015-01-01

    Both cocaine and social interaction place preference conditioning lead to increased neuronal expression of the immediate early gene EGR1 in the nucleus accumbens, a central region of the reward pathway, suggesting that both drug and natural rewards may be processed in similar brain regions. In order to gain novel insights into the intrinsic in vitro electrical activity of the nucleus accumbens and adjacent brain regions and to explore the effects of reward conditioning on network activity, we performed multielectrode array recordings of spontaneous firing in acute brain slices of mice conditioned to either cocaine or social interaction place preference. Cocaine conditioning increased the spike frequency of neurons in the septal nuclei, whereas social interaction conditioning increased the spike frequency in the nucleus accumbens compared to saline control animals. In addition, social interaction conditioning decreased the amount of active neuron clusters in the nucleus accumbens. Our findings suggest that place preference conditioning for both drug and natural rewards may induce persistent changes in neuronal network activity in the nucleus accumbens and the septum that are still preserved in acute slice preparations. PMID:25592253

  17. On the photon production in nucleus-nucleus collisions at high energy

    International Nuclear Information System (INIS)

    A modified Landau hydrodynamical model is applied to study hard thermal photon production at central heavy-ion collisions at LHC, RHIC and SPS energies. It is shown that phase transition of quark-gluon plasma - hadrons in consequence of the thermodynamical expansion is close to the second order phase transition if a resonance production is taken into account. 40 refs., 3 figs

  18. Heavy quarks in proton-nucleus collisions - the hybrid formalism

    CERN Document Server

    Altinoluk, Tolga; Beuf, Guillaume; Kovner, Alex; Lublinsky, Michael

    2015-01-01

    We explore the quark mass effects on inclusive hadron production in proton-nucleus collisions at high energies. We consider two processes. First, we compute the single inclusive cross-section for production of hadrons with open heavy flavour in the proton forward direction at leading order. Next, in the same kinematics, we calculate the heavy-quark contribution to single inclusive production of light or unidentified hadrons at next-to-leading-order. For both studies we exploit the hybrid formalism, that is the collinear factorisation on the proton side while high-density and high-energy effects are resummed on the side of the nucleus.

  19. Formation and decay of a hot compound nucleus

    International Nuclear Information System (INIS)

    The compound nucleus plays an important role in nuclear reactions over a wide range of projectile-target combinations and energies. The limits that angular momentum places on its formation and existence are, for the most part, well understood. The limits on its excitation energy are not as clear. Here we first analyze general geometrical and thermodynamical features of a hot compound nucleus. We then discuss the manners by which it can decay and close by speculating on the high energy limit to its formation and existence. (author)

  20. Recent Developments in Neutrino/Antineutrino-Nucleus Interactions

    Directory of Open Access Journals (Sweden)

    Jorge G. Morfín

    2012-01-01

    Full Text Available Recent experimental results and developments in the theoretical treatment of neutrino-nucleus interactions in the energy range of 1–10 GeV are discussed. Difficulties in extracting neutrino-nucleon cross sections from neutrino-nucleus scattering data are explained and significance of understanding nuclear effects for neutrino oscillation experiments is stressed. Detailed discussions of the status of two-body current contribution in the kinematic region dominated by quasielastic scattering and specific features of partonic nuclear effects in weak DIS scattering are presented.

  1. An occultation of the inner Seyfert nucleus of NGC 4151

    International Nuclear Information System (INIS)

    The brightness of the unresolved nucleus of NGC 4151 was monitored over five months in 1983. Variations of ≅ 0.1 mag/day were observed in the U-band and no significant variation was found of the -OIII] 5007 A emission line. However, an event that was observed on the nights of the 10/11 and 11/12 February 1983 in the continuum around 5672 A has all the characteristics of an occultation. It is proposed that an inner synchrotron nucleus of ≅ 3 a.u. diameter was occulted by an opaque cloud ≅ 6 a.u. across on those two nights

  2. Weak interaction and nucleus: the relationship keeps on

    International Nuclear Information System (INIS)

    This document gathers the lectures made at the Joliot-Curie international summer school in 2003 whose theme, that year, was the relationship between weak interaction and nucleus. There were 8 contributions whose titles are: 1) before the standard model: from beta decay to neutral currents; 2) the electro-weak theory and beyond; 3) testing of the standard model at low energies; 4) description of weak processes in nuclei; 5) 20.000 tonnes underground, an approach to the neutrino-nucleus interaction; 6) parity violation from atom to nucleon; 7) how neutrinos got their masses; and 8) CP symmetry

  3. Final State Interactions Effects in Neutrino-Nucleus Interactions

    Energy Technology Data Exchange (ETDEWEB)

    Golan, Tomasz [Univ. of Wroctaw (Poland); Juszczak, Cezary [Univ. of Wroctaw (Poland); Sobczyk, Jan T. [Fermi National Accelerator Laboratory (FNAL), Batavia, IL (United States)

    2012-07-01

    Final State Interactions effects are discussed in the context of Monte Carlo simulations of neutrino-nucleus interactions. A role of Formation Time is explained and several models describing this effect are compared. Various observables which are sensitive to FSI effects are reviewed including pion-nucleus interaction and hadron yields in backward hemisphere. NuWro Monte Carlo neutrino event generator is described and its ability to understand neutral current $\\pi^0$ production data in $\\sim 1$ GeV neutrino flux experiments is demonstrated.

  4. Hyper deformation and clustering configuration in 168Yb nucleus

    International Nuclear Information System (INIS)

    Recently an exhaustive experimental search for hyper deformation in 168Yb with β ∼ 1.0 and axis ratio 3:1 at spins 70-80ℎ has yielded negative result which is attributed either to the fact that the fission of the compound nucleus prevented population of hyper deformed states or that the amount of angular momentum brought into the compound system was not sufficient to allow population of hyper deformed states. A systematic theoretical search for detection of such hyper deformation in this nucleus using the cranked Nilsson Strutinsky method with tuning to fixed spins was undertaken

  5. Examination of the fission time of the Z =120 nucleus

    Science.gov (United States)

    Sikdar, A. K.; Ray, A.; Chatterjee, A.

    2016-04-01

    We show that the large difference in the measured lifetime for asymmetric fission of the highly excited (T ≈1.5 -MeV ) Z =120 nucleus as measured by the atomic techniques (crystal blocking and x-ray methods) with those measured by the nuclear techniques (mass-angle distribution and prefission neutron multiplicity) cannot be due to the different sensitivities of the atomic and nuclear techniques in different time domains. The claim of formation of a superheavy Z =120 nucleus with a high fission barrier on the basis of an observed long fission time by the atomic techniques is in direct conflict with all other available measurements and calculations.

  6. Electromagnetic properties of the Beryllium-11 nucleus in Halo EFT

    OpenAIRE

    Hammer H.-W.; Phillips D.R.

    2010-01-01

    We compute electromagnetic properties of the Beryllium-11 nucleus using an effective field theory that exploits the separation of scales in this halo system. We fix the parameters of the EFT from measured data on levels and scattering lengths in the 10Be plus neutron system. We then obtain predictions for the B(E1) strength of the 1/2+ to 1/2− transition in the 11Be nucleus. We also compute the charge radius of the ground state of 11Be. Agreement with experiment within the expected accurac...

  7. Sensitivity of reaction cross sections to halo nucleus density distributions

    OpenAIRE

    Alkhazov, G. D.; Sarantsev, V. V.

    2013-01-01

    In order to clear up the sensitivity of the nucleus--nucleus reaction cross sections $\\sigma_R$ to the nuclear matter distributions in exotic halo nuclei, we have calculated the values of $\\sigma_R$ for scattering of $^6$He, $^{11}$Li, and $^{19}$C nuclei on several nuclear targets at the energy of 0.8 GeV/nucleon. The calculations were performed in the "rigid target" approximation to the Glauber theory, different shapes of the nuclear density distributions in $^6$He, $^{11}$Li, and $^{19}$C ...

  8. Internal-nuclear conversion of energy of nucleus excited state

    International Nuclear Information System (INIS)

    In the work an effect of penetration electrons of internal conversion showing in hindered M1-transitions was studied. At the moment of a nucleus transition from excited state in low state, electron of atomic shell can appear inside a nucleus and the internal conversion of electrons occur. For such transitions nuclear parameter do not equal zero. The analytical method of definition of nuclear parameter is offered from the relation of intensities L1/L2, L1/L3, L2/L3 of internal conversion of electrons. (authors)

  9. Formation and decay of a hot compound nucleus

    Energy Technology Data Exchange (ETDEWEB)

    Carlson, B.V.; Dalmolin, F.T.; Dutra, M.; Santos, T.J., E-mail: brett@ita.br [Instituto Tecnologico de Aeronautica (ITA), Sao Jose dos Campos SP (Brazil); Souza, S.R. [Universidade Federal de Rio Grande do Sul (UFRS), Porto Alegre RS, (Brazil); Universidade Federal de Rio de Janeiro (UFRJ), RJ (Brazil). Instituto de Fisica; Donangelo, R. [Instituto de Fisica, Universidad de la Republica de Uruguay, Montevideo (Uruguay); Universidade Federal de Rio Grande do Sul (UFRS), Porto Alegre RS, (Brazil)

    2014-07-01

    The compound nucleus plays an important role in nuclear reactions over a wide range of projectile-target combinations and energies. The limits that angular momentum places on its formation and existence are, for the most part, well understood. The limits on its excitation energy are not as clear. Here we first analyze general geometrical and thermodynamical features of a hot compound nucleus. We then discuss the manners by which it can decay and close by speculating on the high energy limit to its formation and existence. (author)

  10. Spectra Statistics for the Odd-Odd Nucleus 86Nb

    Institute of Scientific and Technical Information of China (English)

    ZHENG Ren-Rong; ZHU Shun-Quan; CHENG Nan-Pu

    2001-01-01

    The energy levels of the odd-odd nucleus 86 Nb at low spins are calculated by using quasi-particles plus a rotor model. The distribution of the nearest-neighbour spacing and the spectral rigidity are studied. We find that the chaotic degree of the energy spectra increases with the increasing spin and reaches a maximum at I = 10; then it decreases gradually for spins above I = 10. The recoil term in the model Haniltonian makes the energy spectra slightly regular. The Coriolis force, however, makes the spectra chaotic and plays a major role in the spectral statistics of the odd-odd nucleus 86Nb.

  11. Gravitational torques imply molecular gas inflow towards the nucleus of M51

    CERN Document Server

    Querejeta, M; Schinnerer, E; García-Burillo, S; Dobbs, C; Colombo, D; Dumas, G; Hughes, A; Kramer, C; Leroy, A; Pety, J; Schuster, K; Thompson, T

    2015-01-01

    The transport of gas towards the centre of galaxies is critical for black hole feeding and, indirectly, it can control active galactic nucleus (AGN) feedback. We have quantified the molecular gas inflow in the central R<1kpc of M51 to be 1 Msun/yr, using a new gravitational torque map and the molecular gas traced by the PdBI Arcsecond Whirlpool Survey (PAWS). The nuclear stellar bar is responsible for this gas inflow. We have also used torque profiles to estimate the location of dynamical resonances, suggesting a corotation for the bar at R~20", and a corotation for the spiral at R~100". We demonstrate how important it is to correct 3.6um images for dust emission in order to compute gravitational torques, and we carefully examine further sources of uncertainty. Our observational measurement of gas inflow can be compared with nuclear molecular outflow rates and provide useful constraints for numerical simulations.

  12. Neuroglobin expression in the rat suprachiasmatic nucleus: colocalization, innervation, and response to light

    DEFF Research Database (Denmark)

    Hundahl, C A; Hannibal, J; Fahrenkrug, J;

    2010-01-01

    Neuroglobin (Ngb) is a myoglobin-like (Mb) heme-globin, belonging the globin family located only in neuronal tissue of the central nervous system. Ngb has been shown to be upregulated in and to protect neurons from hypoxic and ischemic injury, but the function of Ngb-in particular how Ngb may...... localization, colocalization, innervation, and response to light of Ngb-immunoreactive (IR) cells in the rat suprachiasmatic nucleus (SCN). Our results demonstrate that the majority of Ngb-expressing neurons in the SCN belong to a cell group not previously characterized by neurotransmitter content; only a...... small portion was found to co-store GRP in the ventral SCN. Furthermore, some Ngb-containing neurons were responsive to light stimulation at late night evaluated by the induction of cFOS and only a few cells were found to express the core clock gene PER1 during the 24-hour light/dark cycle. The Ngb...

  13. Outflowing Diffuse Gas in the Active Galactic Nucleus of NGC 1068

    CERN Document Server

    Geballe, T R; Oka, T

    2015-01-01

    Spectra of the archetypal Type II Seyfert galaxy NGC 1068 in a narrow wavelength interval near 3.7 microns have revealed a weak absorption feature due to two lines of the molecular ion H3+. The observed wavelength of the feature corresponds to velocity of -70 km/s relative to the systemic velocity of the galaxy, implying an outward flow from the nucleus along the line of sight. The absorption by H3+ along with the previously known broad hydrocarbon absorption at 3.4~microns probably are formed in diffuse gas that is in close proximity to the continuum source, i.e. within a few tens of parsecs of the central engine. Based on that conclusion and the measured H3+ absorption velocity and with the assumption of a spherically symmetric wind we estimate a rate of mass outflow from the AGN of ~1 Msun/yr.

  14. Photo-Disintegration of the Iron Nucleus in Fractured Magnetite Rocks with Magnetostriction

    CERN Document Server

    Widom, A; Srivastava, Y N

    2013-01-01

    There has been considerable interest in recent experiments on iron nuclear disintegrations observed when rocks containing such nuclei are crushed and fractured. The resulting nuclear transmutations are particularly strong for the case of magnetite rocks, i.e. loadstones. We argue that the fission of the iron nucleus is a consequence of photo-disintegration. The electro-strong coupling between electromagnetic fields and nuclear giant dipole resonances are central for producing observed nuclear reactions. The large electron energies produced during the fracture of piezomagnetic rocks are closely analogous to the previously discussed case of the fracture of piezoelectric rocks. In both cases electro-weak interactions can produce neutrons and neutrinos from energetic protons and electrons thus inducing nuclear transmutations. The electro-strong condensed matter coupling discussed herein represents new many body collective nuclear photo-disintegration effects.

  15. Mefloquine in the nucleus accumbens promotes social avoidance and anxiety-like behavior in mice.

    Science.gov (United States)

    Heshmati, Mitra; Golden, Sam A; Pfau, Madeline L; Christoffel, Daniel J; Seeley, Elena L; Cahill, Michael E; Khibnik, Lena A; Russo, Scott J

    2016-02-01

    Mefloquine continues to be a key drug used for malaria chemoprophylaxis and treatment, despite reports of adverse events like depression and anxiety. It is unknown how mefloquine acts within the central nervous system to cause depression and anxiety or why some individuals are more vulnerable. We show that intraperitoneal injection of mefloquine in mice, when coupled to subthreshold social defeat stress, is sufficient to produce depression-like social avoidance behavior. Direct infusion of mefloquine into the nucleus accumbens (NAc), a key brain reward region, increased stress-induced social avoidance and anxiety behavior. In contrast, infusion into the ventral hippocampus had no effect. Whole cell recordings from NAc medium spiny neurons indicated that mefloquine application increases the frequency of spontaneous excitatory postsynaptic currents, a synaptic adaptation that we have previously shown to be associated with increased susceptibility to social defeat stress. Together, these data demonstrate a role for the NAc in mefloquine-induced depression and anxiety-like behaviors. PMID:26471420

  16. Sexual differentiation of the bed nucleus of the stria terminalis in humans may extend into adulthood.

    Science.gov (United States)

    Chung, Wilson C J; De Vries, Geert J; Swaab, Dick F

    2002-02-01

    Gonadal steroids have remarkable developmental effects on sex-dependent brain organization and behavior in animals. Presumably, fetal or neonatal gonadal steroids are also responsible for sexual differentiation of the human brain. A limbic structure of special interest in this regard is the sexually dimorphic central subdivision of the bed nucleus of the stria terminalis (BSTc), because its size has been related to the gender identity disorder transsexuality. To determine at what age the BSTc becomes sexually dimorphic, the BSTc volume in males and females was studied from midgestation into adulthood. Using vasoactive intestinal polypeptide and somatostatin immunocytochemical staining as markers, we found that the BSTc was larger and contains more neurons in men than in women. However, this difference became significant only in adulthood, showing that sexual differentiation of the human brain may extend into the adulthood. The unexpectedly late sexual differentiation of the BSTc is discussed in relation to sex differences in developmental, adolescent, and adult gonadal steroid levels. PMID:11826131

  17. Microscopic optical potential with two and three body forces for nucleon–nucleus scattering

    Directory of Open Access Journals (Sweden)

    Gambhir Y.K.

    2014-03-01

    Full Text Available The proton - nucleus optical potentials generated by folding the calculated complex, density and energy dependent g- matrices (with and without three-body forces (TBF: Urbana IX (UVIX and TNI over the target nucleon density distributions obtained from the relativistic mean field theory, are used for the calculation of the differential cross section dσ / dθ , polarization Ay , spin rotation function (Q. for 65 and 200 MeV polarized proton incident on 40Ca and 208Pb . The agreement with the experiment is rather impressive. It is found that the inclusion of TBF (Urbana IX UVIX and TNI reduces the strength of the central part of the optical potential in the nuclear interior and affects the calculated spin-orbit potential only marginally and leads to an improvement in the agreement with the corresponding experimental results.

  18. Effects of negative-energy propagations in deuteron-nucleus scattering

    International Nuclear Information System (INIS)

    The effects of negative-energy propagations in the effective optical potentials for relativistic deuteron-nucleus elastic scattering are investigated utilizing the Breit approach. First, we consider the effects of the (+-) and (-+) propagations. They represent that one of the nucleons in the deuteron propagates in its positive-energy state, while another propagates in negative-energy one. Second, the effects of the (--) propagation, which represents that both the nucleons propagate in their negative-energy states, are studies. It has been found that the characteristic features of the optical potentials near 400 MeV - the wine-bottle-bottom-shape of the central part and the enhanced spin-orbit strength - are pure relativistic effects mainly due to the (+-) and (-+) propagations, whereas the effects of the (--) propagation are small. (author)

  19. Delivering Single-Walled Carbon Nanotubes to the Nucleus Using Engineered Nuclear Protein Domains.

    Science.gov (United States)

    Boyer, Patrick D; Ganesh, Sairaam; Qin, Zhao; Holt, Brian D; Buehler, Markus J; Islam, Mohammad F; Dahl, Kris Noel

    2016-02-10

    Single-walled carbon nanotubes (SWCNTs) have great potential for cell-based therapies due to their unique intrinsic optical and physical characteristics. Consequently, broad classes of dispersants have been identified that individually suspend SWCNTs in water and cell media in addition to reducing nanotube toxicity to cells. Unambiguous control and verification of the localization and distribution of SWCNTs within cells, particularly to the nucleus, is needed to advance subcellular technologies utilizing nanotubes. Here we report delivery of SWCNTs to the nucleus by noncovalently attaching the tail domain of the nuclear protein lamin B1 (LB1), which we engineer from the full-length LMNB1 cDNA. More than half of this low molecular weight globular protein is intrinsically disordered but has an immunoglobulin-fold composed of a central hydrophobic core, which is highly suitable for associating with SWCNTs, stably suspending SWCNTs in water and cell media. In addition, LB1 has an exposed nuclear localization sequence to promote active nuclear import of SWCNTs. These SWCNTs-LB1 dispersions in water and cell media display near-infrared (NIR) absorption spectra with sharp van Hove peaks and an NIR fluorescence spectra, suggesting that LB1 individually disperses nanotubes. The dispersing capability of SWCNTs by LB1 is similar to that by albumin proteins. The SWCNTs-LB1 dispersions with concentrations ≥150 μg/mL (≥30 μg/mL) in water (cell media) remain stable for ≥75 days (≥3 days) at 4 °C (37 °C). Further, molecular dynamics modeling of association of LB1 with SWCNTs reveal that the exposure of the nuclear localization sequence is independent of LB1 binding conformation. Measurements from confocal Raman spectroscopy and microscopy, NIR fluorescence imaging of SWCNTs, and fluorescence lifetime imaging microscopy show that millions of these SWCNTs-LB1 complexes enter HeLa cells, localize to the nucleus of cells, and interact with DNA. We postulate that the

  20. Central Pain Syndrome

    Science.gov (United States)

    ... Enhancing Diversity Find People About NINDS NINDS Central Pain Syndrome Information Page Table of Contents (click to ... being done? Clinical Trials Organizations What is Central Pain Syndrome? Central pain syndrome is a neurological condition ...

  1. Analysis of Intermediate-Energy Nucleus-Nucleus Spallation, Fission, and Fragmentation Reactions with the LAQGSM code

    CERN Document Server

    Mashnik, S G; Prael, R E; Sierk, A J

    2003-01-01

    The LAQGSM code has been recently developed at Los Alamos National Laboratory to simulate nuclear reactions for proton radiography applications. We have benchmarked our code against most available measured data both for proton-nucleus and nucleus-nucleus interactions at incident energies from 10 MeV to 800 GeV and have compared our results with predictions of other current models used by the nuclear community. Here, we present a brief description of our code and show illustrative results obtained with LAQGSM for neutron spectra measured recently by Nakamura's groups for reactions induced by light and medium nuclei on targets from C to Pb at several incident energies from 95 to 600 MeV/nucleon and with the recent GSI measurements of spallation, fission, and fragmentation yields from A+p and A+A reactions at incident energies near and below 1 GeV/nucleon. Further necessary work is outlined.

  2. Autoradiographic distribution of 125I-galanin binding sites in the rat central nervous system

    International Nuclear Information System (INIS)

    Galanin (GAL) binding sites in coronal sections of the rat brain were demonstrated using autoradiographic methods. Scatchard analysis of 125I-GAL binding to slide-mounted tissue sections revealed saturable binding to a single class of receptors with a Kd of approximately 0.2 nM. 125I-GAL binding sites were demonstrated throughout the rat central nervous system. Dense binding was observed in the following areas: prefrontal cortex, the anterior nuclei of the olfactory bulb, several nuclei of the amygdaloid complex, the dorsal septal area, dorsal bed nucleus of the stria terminalis, the ventral pallidum, the internal medullary laminae of the thalamus, medial pretectal nucleus, nucleus of the medial optic tract, borderline area of the caudal spinal trigeminal nucleus adjacent to the spinal trigeminal tract, the substantia gelatinosa and the superficial layers of the dorsal spinal cord. Moderate binding was observed in the piriform, periamygdaloid, entorhinal, insular cortex and the subiculum, the nucleus accumbens, medial forebrain bundle, anterior hypothalamic, ventromedial, dorsal premamillary, lateral and periventricular thalamic nuclei, the subzona incerta, Forel's field H1 and H2, periventricular gray matter, medial and superficial gray strata of the superior colliculus, dorsal parts of the central gray, peripeduncular area, the interpeduncular nucleus, substantia nigra zona compacta, ventral tegmental area, the dorsal and ventral parabrachial and parvocellular reticular nuclei. The preponderance of GAL-binding in somatosensory as well as in limbic areas suggests a possible involvement of GAL in a variety of brain functions

  3. Dietary grape seed polyphenols repress neuron and glia activation in trigeminal ganglion and trigeminal nucleus caudalis

    Directory of Open Access Journals (Sweden)

    Durham Paul L

    2010-12-01

    Full Text Available Abstract Background Inflammation and pain associated with temporomandibular joint disorder, a chronic disease that affects 15% of the adult population, involves activation of trigeminal ganglion nerves and development of peripheral and central sensitization. Natural products represent an underutilized resource in the pursuit of safe and effective ways to treat chronic inflammatory diseases. The goal of this study was to investigate effects of grape seed extract on neurons and glia in trigeminal ganglia and trigeminal nucleus caudalis in response to persistent temporomandibular joint inflammation. Sprague Dawley rats were pretreated with 200 mg/kg/d MegaNatural-BP grape seed extract for 14 days prior to bilateral injections of complete Freund's adjuvant into the temporomandibular joint capsule. Results In response to grape seed extract, basal expression of mitogen-activated protein kinase phosphatase 1 was elevated in neurons and glia in trigeminal ganglia and trigeminal nucleus caudalis, and expression of the glutamate aspartate transporter was increased in spinal glia. Rats on a normal diet injected with adjuvant exhibited greater basal levels of phosphorylated-p38 in trigeminal ganglia neurons and spinal neurons and microglia. Similarly, immunoreactive levels of OX-42 in microglia and glial fibrillary acidic protein in astrocytes were greatly increased in response to adjuvant. However, adjuvant-stimulated levels of phosphorylated-p38, OX-42, and glial fibrillary acidic protein were significantly repressed in extract treated animals. Furthermore, grape seed extract suppressed basal expression of the neuropeptide calcitonin gene-related peptide in spinal neurons. Conclusions Results from our study provide evidence that grape seed extract may be beneficial as a natural therapeutic option for temporomandibular joint disorders by suppressing development of peripheral and central sensitization.

  4. Thermally active TRPV1 tonically drives central spontaneous glutamate release

    OpenAIRE

    Shoudai, Kiyomitsu; Peters, James H.; McDougall, Stuart J.; Fawley, Jessica A.; Andresen, Michael C.

    2010-01-01

    Central synapses spontaneously release neurotransmitter at low rates. In brainstem, cranial visceral afferent terminals in caudal solitary tract nucleus (NTS) display pronounced activity-dependent asynchronous release of glutamate and this extra release depends on TRPV1 receptors (TRPV1+). Asynchronous release is absent for afferents lacking TRPV1 (TRPV1-) and resting EPSC frequency was greater in TRPV1+. Here, we studied this basal activity difference by assessing thermal sensitivity of spon...

  5. A comparative analysis of mechanisms of fast light particles production in nucleus-nucleus collisions at low and intermediate energies

    CERN Document Server

    Denikin, A S

    2002-01-01

    The dynamics and the mechanisms of formation of pre-equilibrium light particles in nucleus-nucleus collisions at low and intermediate energies are discussed in terms of a classical four-body model. The energy and angular distributions of light particles have been calculated. It has been found that at energies lower than 50A MeV the formation of the most high-energy part of the nuclear spectrum occurs at the expense of the acceleration of light target particles with the mean field of the projectile. The obtained data are in good agreement with available experimental data

  6. Gustatory neural responses to umami stimuli in the parabrachial nucleus of C57BL/6J mice

    OpenAIRE

    Tokita, Kenichi; Yamamoto, Takashi; Boughter, John D

    2011-01-01

    Umami is considered to be the fifth basic taste quality and is elicited by glutamate. The mouse is an ideal rodent model for the study of this taste quality because of evidence that suggests that this species, like humans, may sense umami-tasting compounds as unique from other basic taste qualities. We performed single-unit recording of taste responses in the parabrachial nucleus (PbN) of anesthetized C57BL/6J mice to investigate the central representation of umami taste. A total of 52 taste-...

  7. Multiplicities and angular distributions of nucleus-nucleus interactions at SPS energies protons to lead

    CERN Document Server

    Cherry, M L; Dabrowska, A; Dugas, J; Holynski, R; Jones, W V; Kudzia, D; Nilsson, B S; Olszewski, A; Szarska, M; Trzupek, A; Waddington, C Jake; Wefel, J P; Wilczynska, B; Wilczynski, H; Wolter, W; Wosiek, B; Wozniak, K

    1997-01-01

    Charged particle multiplicities from high multiplicity interactions of 158 GeV/n Pb ions on Pb targets were measured in nuclear emulsion chambers. These measurements are compared to measurements of central interactions of 200 GeV/n p, O, and S beams on silver or bromine and to simulations from the FRITIOF 7.02 and Venus 4.12 Monte Carlo event generators. Multiplicities in the central region are significantly lower than either simulation predicts. Venus, the only one of the two which attempts to incorporate reinteraction phenomena, predicts a significant narrowing of the pseudorapidity distribution for the highest multiplicity events, which is not observed in the data. However, we do find evidence for unexpectedly high spectator proton transverse momenta. (6 refs).

  8. Energy dependence of hyperon production in nucleus-nucleus collisions at SPS

    CERN Document Server

    Antinori, F; Badalà, A; Barbera, R; Belogianni, A; Bhasin, A; Bloodworth, Ian J; Bombara, M; Bruno, G; Bull, S A; Caliandro, R; Campbell, M; Carena, W; Carrer, N; Clarke, R F; Dainese, A; De Haas, A P; De Rijke, P C; Di Bari, D; Di Liberto, S; Divià, R; Elia, D; Evans, D; Feofilov, G A; Fini, R A; Ganoti, P; Ghidini, B; Grella, G; Helstrup, H; Hetland, K F; Holme, A K; Jacholkowski, A; Jones, G T; Jovanovic, P; Jusko, A; Kamermans, R; Kinson, J B; Knudson, K; Kolojvari, A A; Kondratiev, V; Králik, I; Kravcakova, A; Kuijer, P; Lenti, V; Lietava, R; Løvhøiden, G; Manzari, V; Martinská, G; Mazzoni, M A; Meddi, F; Michalon, A; Morando, M; Nappi, E; Navach, F; Norman, P I; Palmeri, A; Pappalardo, G S; Pastircák, B; Pisút, J; Pisútová, N; Posa, F; Quercigh, Emanuele; Riggi, F; Röhrich, D; Romano, G; Safarík, K; Sándor, L; Schillings, E; Segato, G F; Sené, M; Sené, R; Snoeys, W; Soramel, F; Spyropoulou-Stassinaki, M; Staroba, P; Toulina, T A; Turrisi, R; Tveter, T S; Urbán, J; Valiev, F F; Van den Brink, A; Van de Ven, P; Van de Vyvre, P; van Eijndhoven, N; Van Hunen, J J; Vascotto, Alessandro; Vik, T; Villalobos Baillie, O; Vinogradov, L I; Virgili, T; Votruba, M F; Vrláková, J; Závada, P

    2004-01-01

    A measurement of strange baryon and antibaryon production in Pb-Pb collisions has been carried out by the NA57 experiment at the CERN SPS, with 40 and 158 A GeV/c beam momentum. Results on $\\Lambda$, $\\Xi$ and $\\Omega$ hyperon yields at mid-rapidity in the most central 53% of Pb-Pb collisions at 40 A GeV/c are presented and compared with those obtained at higher energy, in the same collision centrality range. The $\\Lambda$ and $\\Xi^-$ yields per unit rapidity stay roughly constant while those of $\\Omega^-$, $\\bar\\Lambda$, $\\bar\\Xi^+$ and $\\bar\\Omega^+$ increase when going to the higher SPS energy. Hyperon yields at the SPS are compared with those from the STAR experiment in $\\sqrt{s_{NN}}$ = 130 GeV Au-Au collisions at RHIC.

  9. Energy Dependence of Particle Production in nucleus-nucleus collisions at the CERN SPS

    OpenAIRE

    van Leeuwen, M.(Institute for Subatomic Physics of Utrecht University, Utrecht, Netherlands); Collaboration, for the NA62

    2003-01-01

    New preliminary results on kaon and pion production in central 30AGeV Pb+Pb collisions are presented. The data are compared to data at lower and higher energies to examine the energy dependence of the kaon to pion ratios and the inverse slope parameters of kaons. The results are compared to expectations from models with and without a phase transition to the Quark Gluon Plasma.

  10. Universal Services: Nucleus for a Social European Private Law

    OpenAIRE

    MICKLITZ, Hans-Wolfgang

    2009-01-01

    The paper is intended to develop the idea that the growing number of rules on universal services allows for the introduction of a debate about whether these rules contain the nucleus of a new social European private law. This all the more important as the European Community will change the social character of consumer law by means of full harmonization.

  11. Theory status of quarkonium production in proton-nucleus collisions

    CERN Document Server

    Lansberg, J P

    2015-01-01

    I give a brief overview of the recent theoretical progress in the study of quarkonium production in proton-nucleus collisions in view of the recent LHC and RHIC results. A special emphasis is put on the excited states such as the psi', Upsilon(2S) and Upsilon(3S).

  12. Three-dimensional organization of the human interphase nucleus

    NARCIS (Netherlands)

    T.A. Knoch (Tobias); C. Münkel (Christian); W. Waldeck (Waldemar); J. Langowski (Jörg)

    2000-01-01

    textabstractDespite the successful linear sequencing of the human genome its three-dimensional structure is widely unknown, although it is important for gene regulation and replication. For a long time the interphase nucleus has been viewed as a 'spaghetti soup' of DNA without much internal structur

  13. CTP synthase forms cytoophidia in the cytoplasm and nucleus

    International Nuclear Information System (INIS)

    CTP synthase is an essential metabolic enzyme responsible for the de novo synthesis of CTP. Multiple studies have recently showed that CTP synthase protein molecules form filamentous structures termed cytoophidia or CTP synthase filaments in the cytoplasm of eukaryotic cells, as well as in bacteria. Here we report that CTP synthase can form cytoophidia not only in the cytoplasm, but also in the nucleus of eukaryotic cells. Both glutamine deprivation and glutamine analog treatment promote formation of cytoplasmic cytoophidia (C-cytoophidia) and nuclear cytoophidia (N-cytoophidia). N-cytoophidia are generally shorter and thinner than their cytoplasmic counterparts. In mammalian cells, both CTP synthase 1 and CTP synthase 2 can form cytoophidia. Using live imaging, we have observed that both C-cytoophidia and N-cytoophidia undergo multiple rounds of fusion upon glutamine analog treatment. Our study reveals the coexistence of cytoophidia in the cytoplasm and nucleus, therefore providing a good opportunity to investigate the intracellular compartmentation of CTP synthase. - Highlights: • CTP synthase forms cytoophidia not only in the cytoplasm but also in the nucleus. • Glutamine deprivation and Glutamine analogs promotes cytoophidium formation. • N-cytoophidia exhibit distinct morphology when compared to C-cytoophidia. • Both CTP synthase 1 and CTP synthase 2 form cytoophidia in mammalian cells. • Fusions of cytoophidia occur in the cytoplasm and nucleus

  14. Inclusive jet production in ultrarelativistic proton-nucleus collisions

    CERN Document Server

    Perepelitsa, Dennis

    High-$p_\\mathrm{T}$ processes in proton- and deuteron-nucleus collisions at TeV energies are the best presently available way to study the partonic structure of the nucleus in a high-density regime. Jet production over a wide range of phase space can significantly constrain the current knowledge of nuclear parton distribution functions (nPDFs), which are substantially less well understood than the corresponding PDFs in protons and which have only recently begun to be treated in a spatially-dependent way. An accurate knowledge of nPDFs is crucial for a definitive control of perturbative processes in a cold nuclear environment, since high-$p_\\mathrm{T}$ probes are used to quantitatively investigate the hot QCD matter created in ultrarelativistic nucleus-nucleus collisions. Furthermore, jets from low Bjorken-$x$ partons can probe the transition from the dilute to saturated nuclear regimes. Jet production is investigated in $d$+Au collisions at $\\sqrt{s} = 200$ GeV with the PHENIX detector at the Relativistic Hea...

  15. Nucleus accumbens dopamine receptors in the consolidation of spatial memory.

    NARCIS (Netherlands)

    Mele, A.; Avena, M.; Roullet, P.; Leonibus, E. de; Mandillo, S.; Sargolini, F.; Coccurello, R.; Oliverio, A.

    2004-01-01

    Nucleus accumbens dopamine is known to play an important role in motor activity and in behaviours governed by drugs and natural reinforcers, as well as in non-associative forms of learning. At the same time, activation of D1 and D2 dopamine receptors has been suggested to promote intracellular event

  16. CTP synthase forms cytoophidia in the cytoplasm and nucleus

    Energy Technology Data Exchange (ETDEWEB)

    Gou, Ke-Mian [MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT (United Kingdom); State Key Laboratory for Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing 100193 (China); Chang, Chia-Chun [Institute of Biotechnology, National Taiwan University, Taipei, Taiwan, ROC (China); Shen, Qing-Ji [MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT (United Kingdom); Sung, Li-Ying, E-mail: liyingsung@ntu.edu.tw [Institute of Biotechnology, National Taiwan University, Taipei, Taiwan, ROC (China); Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan, ROC (China); Liu, Ji-Long, E-mail: jilong.liu@dpag.ox.ac.uk [MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT (United Kingdom)

    2014-04-15

    CTP synthase is an essential metabolic enzyme responsible for the de novo synthesis of CTP. Multiple studies have recently showed that CTP synthase protein molecules form filamentous structures termed cytoophidia or CTP synthase filaments in the cytoplasm of eukaryotic cells, as well as in bacteria. Here we report that CTP synthase can form cytoophidia not only in the cytoplasm, but also in the nucleus of eukaryotic cells. Both glutamine deprivation and glutamine analog treatment promote formation of cytoplasmic cytoophidia (C-cytoophidia) and nuclear cytoophidia (N-cytoophidia). N-cytoophidia are generally shorter and thinner than their cytoplasmic counterparts. In mammalian cells, both CTP synthase 1 and CTP synthase 2 can form cytoophidia. Using live imaging, we have observed that both C-cytoophidia and N-cytoophidia undergo multiple rounds of fusion upon glutamine analog treatment. Our study reveals the coexistence of cytoophidia in the cytoplasm and nucleus, therefore providing a good opportunity to investigate the intracellular compartmentation of CTP synthase. - Highlights: • CTP synthase forms cytoophidia not only in the cytoplasm but also in the nucleus. • Glutamine deprivation and Glutamine analogs promotes cytoophidium formation. • N-cytoophidia exhibit distinct morphology when compared to C-cytoophidia. • Both CTP synthase 1 and CTP synthase 2 form cytoophidia in mammalian cells. • Fusions of cytoophidia occur in the cytoplasm and nucleus.

  17. Parity non-conserving effects in neutron-nucleus scattering

    International Nuclear Information System (INIS)

    The present lecture reviews the motivations which led to study the contribution of the neutron-nucleus component to parity-non-conserving effects observed in medium-heavy nuclei and considers its present status. It is shown that it cannot account for those experimental data. The order interpretation of these effects, which cannot lead to precise statements, is schematically described

  18. Exotic atoms, K-nucleus scattering and hypernuclei

    International Nuclear Information System (INIS)

    Recent progress in exotic atom physics, kaon-nucleus scattering, and hypernuclear physics is reviewed. Specific problems discussed include searches for muon-nucleon interactions beyond QED, a comparison of data and recent calculation of K+- + 12C elastic and inelastic scattering, as well as recent studies of Σ and Λ hypernuclei including new data on the level structure of 13C/Λ

  19. Electron elastic scattering and quark structure of 3He nucleus

    International Nuclear Information System (INIS)

    It is shown that for the interpretation of the behaviour of the 3He nucleus form factor at transfer momenta q > 6 fmsup(-1) of importance are nine-quark admixtures and their interference with nucleon and six-quark channels

  20. Rapid feedback processing in human nucleus accumbens and motor thalamus

    NARCIS (Netherlands)

    Schüller, T.; Gründler, T.O.J.; Jocham, G.; Klein, T.A.; Timmermann, L.; Visser-Vandewalle, V.E.R.M.; Kuhn, J.

    2015-01-01

    The nucleus accumbens (NAcc) and thalamus are integral parts in models of feedback processing. Deep brain stimulation (DBS) has been successfully employed to alleviate symptoms of psychiatric conditions including obsessive-compulsive disorder (OCD) and Tourette's syndrome (TS). Common target structu

  1. Yrast structure of the shell model nucleus 89Nb

    International Nuclear Information System (INIS)

    In the present work, report on the study of high-spin states in the N = 48 isotone 89Nb, produced through heavy-ion fusion evaporation reaction has been made. The previously known level scheme in this nucleus has been extended to ∼ 10.5 MeV excitation energy and up to spin around 23ħ

  2. First observation of the doubly magic nucleus 78Ni50

    International Nuclear Information System (INIS)

    The doubly magic nucleus of 78Ni has been identified for the first time and the associated production yield was measured in the projectile-fission reaction of 238U on Pb and Be targets at relativistic energies. (K.A.)

  3. The deuteron-nucleus interaction at intermediate energies

    International Nuclear Information System (INIS)

    The relativistic deuteron structure is used to obtain the deuteron nucleus interaction in a relativistic impulse calculation. We conclude that the PESIA multiple-scattering approximation, used in conjunction with a fully-relativistic deuteron wave function, seems to describe reasonably well the scattering data, while other more conventional multiple scattering approximations fail to do so. copyright 1995 American Institute of Physics

  4. Three-dimensional organization of the human interphase nucleus

    NARCIS (Netherlands)

    T.A. Knoch (Tobias); M. Wachsmuth (Malte); W. Waldeck (Waldemar); J. Langowski (Jörg)

    2002-01-01

    markdownabstractTo approach the three-dimensional organization of the human cell nucleus, the structural-, scaling- and dynamic properties of interphase chromosomes and cell nuclei were simulated with Monte Carlo and Brownian Dynamics methods. The 30 nm chromatin fibre was folded according to the Mu

  5. Three-dimensional organization of the human interphase nucleus.

    NARCIS (Netherlands)

    T.A. Knoch (Tobias); M. Wachsmuth (Malte); W. Waldeck (Waldemar); J. Langowski (Jörg)

    2002-01-01

    textabstractTo approach the three-dimensional organization of the human cell nucleus, the structural-, scaling- and dynamic properties of interphase chromosomes and cell nuclei were simulated with Monte Carlo and Brownian Dynamics methods. The 30 nm chromatin fibre was folded according to the Multi-

  6. Three-dimensional organization of the human interphase nucleus

    NARCIS (Netherlands)

    T.A. Knoch (Tobias); M. Wachsmuth (Malte); W. Waldeck (Waldemar); J. Langowski (Jörg)

    2002-01-01

    textabstractTo approach the three-dimensional organization of the human cell nucleus, the structural-, scaling- and dynamic properties of interphase chromosomes and cell nuclei were simulated with Monte Carlo and Brownian Dynamics methods. The 30 nm chromatin fibre was folded according to the Mul

  7. Deexcitation of superdeformed bands in the nucleus Tb-151

    NARCIS (Netherlands)

    Finck, C; Appelbe, D; Beck, FA; Byrski, T; Cullen, D; Curien, D; deFrance, G; Duchene, G; Erturk, S; Haas, B; Khadiri, N; Kharraja, B; Prevost, D; Rigollet, C; Stezowski, O; Twin, P; Vivien, JP; Zuber, K

    1997-01-01

    The aim of this work is to get more informations about the decay-out of superdeformed bands. One of the best candidates in the mass A similar or equal to 150 region for that kind of research is the nucleus Tb-151. From previous works, it has been established that the first excited band goes lower in

  8. Empirical Example of Nucleus with Transitional Dynamical Symmetry X(5)

    Institute of Scientific and Technical Information of China (English)

    张大立; 赵惠英

    2002-01-01

    By analysing the energy spectrum, E2 transition rates and branching ratios, it is shown explicitly that the nucleus 150Nd provides an empirical example with X(5) symmetry at the critical point of the transition from U(5) to SU(3) symmetry.

  9. Neutral pion production in nucleus-nucleus collisions at 158 and 200 GeV/nucleon

    International Nuclear Information System (INIS)

    Two years ago, at the 12th Winter Workshop on Nuclear Dynamics held here in Snowbird, the authors presented WA80 limits on direct photon production in 200-GeV 32S + Au collisions. It was found that the results were consistent (within 1σ) with the absence of an excess of photons over those that can be accounted for by the two-photon decay branches of π0 and η mesons and by the small photon contributions from other radiative decays. They are in the process of finalizing the direct-photon production results from collisions of lead nuclei at 158 GeV/nucleon. The author briefly discusses the status of the analysis and gives some preliminary results at the end of this talk. However, most of this presentation is concerned with a very different aspect of the photon measurements: distributions of neutral pions. In contrast to direct photons which probe initial collision conditions, hadrons, such as neutral pions, interact strongly and decouple late in the reaction evolution and, thus, provide information concerning the system at freeze out. Transverse momentum spectra at low and intermediate pT relate to thermodynamic and hydrodynamic descriptions of the hot, dense systems. In addition, the high-pT region reflects the hard-scattering regime and may help one understand initial-state particle production by forming a bridge to proton-proton and proton-nucleus results. It follows that it is essential that the π0 measurements cover a large pT range

  10. The nature of orbits in a prolate elliptical galaxy model with a bulge and a dense nucleus

    Institute of Scientific and Technical Information of China (English)

    Nicolaos D. Caranicolas; Euaggelos E. Zotos

    2011-01-01

    We study the transition from regular to chaotic motion in a prolate elliptical galaxy dynamical model with a bulge and a dense nucleus.Our numerical investigation shows that stars with angular momentum Lz less than or equal to a critical value Lzc,moving near the galactic plane,are scattered to higher z,when reaching the central region of the galaxy,thus displaying chaotic motion.An inverse square law relationship was found to exist between the radius of the bulge and the critical value Lzc of the angular momentum.On the other hand,a linear relationship exists between the mass of the nucleus and Lzc.The numerically obtained results are explained using theoretical arguments.Our study shows that there are connections between regular or chaotic motion and the physical parameters of the system,such as the star's angular momentum and mass,the scale length of the nucleus and the radius of the bulge.The results are compared with the outcomes of previous work.

  11. Antiproton-nucleus inelastic scattering and the spin-isospin dependence of the N anti N interaction

    International Nuclear Information System (INIS)

    A general overview of the utility of antinucleon (anti N)-nucleus inelastic scattering studies is presented, emphasizing both the sensitivity of the cross sections to various components of the N anti N transition amplitudes and the prospects for the exploration of some novel aspects of nuclear structure. We start with an examination of the relation between NN and N anti N potentials, focusing on the coherences predicted for the central, spin-orbit and tensor components, and how these may be revealed by measurements of two-body spin observables. We next discuss the role of the nucleus as a spin and isospin filter, and show how, by a judicious choice of final state quantum numbers (natural or unnatural parity states, isospin transfer ΔT=0 or 1) and momentum transfer q, one can isolate different components of the N anti N transition amplitude. Various models for the N anti N interaction which give reasonable fits to the available two-body data are shown to lead to strikingly different predictions for certain spin-flip nuclear transitions. We suggest several possible directions for future anti N-nucleus inelastic scattering experiments at LEAR, for instance the study of spin observables which would be accessible with polarized anti N beams, charge exchange reactions, and higher resolution studies of the (anti p, anti p') reaction. We compare the antinucleon and the nucleon as a probe of nuclear modes of excitation. 34 refs

  12. Evidence for a supermassive object in the nucleus of the galaxy M87 from SIT and CCD area photometry

    Science.gov (United States)

    Young, P. J.; Westphal, J. A.; Kristian, J.; Wilson, C. P.; Landauer, F. P.

    1978-01-01

    Results are presented for broadband three-color (BVR) photometric observations of the peculiar elliptical radio galaxy M87, which were obtained with digital two-dimensional SIT and CCD detector systems on the Palomar 60-in. and 200-in. telescopes. The observations and the reduction procedures for the digital data are outlined, the luminosity profile of M87 is given, and a nuclear luminosity spike is found to be centered within 0.02 arcsec of the center of M87. Attempts are made to fit various theoretical models to the luminosity profile, and a satisfactory fit is obtained between the observed profile and a model involving a massive black hole in the galactic nucleus. A model-independent dynamical analysis of the central regions is performed which indicates that the nucleus of M87 contains a supermassive object of about 5 billion solar masses with a radius of no more than 100 pc and an M/L ratio of at least 60. The possible nature of this object is considered, and it is concluded that M87 is probably the most plausible candidate for a massive black hole in a galactic nucleus.

  13. Depolarization and stimulation of neurons in nucleus tractus solitarii by carbon dioxide does not require chemical synaptic input.

    Science.gov (United States)

    Dean, J B; Bayliss, D A; Erickson, J T; Lawing, W L; Millhorn, D E

    1990-01-01

    The effects of elevated CO2 (i.e. hypercapnia) on neurons in the nucleus tractus solitarii were studied using extracellular (n = 82) and intracellular (n = 33) recording techniques in transverse brain slices prepared from rat. Synaptic connections from putative chemosensitive neurons in the ventrolateral medulla were removed by bisecting each transverse slice and discarding the ventral half. In addition, the response to hypercapnia in 20 neurons was studied during high magnesium-low calcium synaptic blockade. Sixty-five per cent of the neurons (n = 75) tested were either insensitive or inhibited by hypercapnia. However, 35% (n = 40) were depolarized and/or increased their firing rate during hypercapnia. Nine out of 10 CO2-excited neurons retained their chemosensitivity to CO2 in the presence of high magnesium-low calcium synaptic blockade medium. Our findings demonstrate that many neurons in the nucleus tractus solitarii were depolarized and/or increased their firing rate during hypercapnia. These neurons were not driven synaptically by putative chemosensitive neurons of the ventrolateral medulla since this region was removed from the slice. Furthermore, because chemosensitivity persisted in most neurons tested during synaptic blockade, we conclude that some neurons in the nucleus tractus solitarii are inherently CO2-chemosensitive. Although the function of dorsal medullary chemosensitive neurons cannot be determined in vitro, their location and their inherent chemosensitivity suggest a role in cardiorespiratory central chemoreception. PMID:2120613

  14. Density waves in the central regions of galaxies

    OpenAIRE

    Emsellem, Eric

    2001-01-01

    Density waves in the central kpc of galaxies, taking the form of spirals, bars and/or lopsided density distributions are potential actors of the redistribution of angular momentum. They thus play an important role in the overall evolution of the central structures, not mentioning the possible link with the active/non-active nucleus. I present here kinematical evidences for the presence of such structures using new sets of observations: two-dimensional (OASIS/CFHT) and long-slit (ISAAC/VLT) sp...

  15. The role of D-serine as co-agonist of NMDA receptors in the nucleus accumbens: relevance to cocaine addiction

    OpenAIRE

    D’Ascenzo, Marcello; Podda, Maria Vittoria; Grassi, Claudio

    2014-01-01

    Cocaine addiction is characterized by compulsive drug use despite adverse consequences and high rate of relapse during periods of abstinence. Increasing consensus suggests that addiction to drugs of abuse usurps learning and memory mechanisms normally related to natural rewards, ultimately producing long-lasting neuroadaptations in the mesocorticolimbic system. This system, formed in part by the ventral tegmental area and nucleus accumbens (NAc), has a central role in the development and expr...

  16. Disruption of the brain-derived neurotrophic factor (BDNF) immunoreactivity in the human Kölliker-Fuse nucleus in victims of unexplained fetal and infant death

    OpenAIRE

    Anna Maria Lavezzi

    2014-01-01

    Experimental studies have demonstrated that the neurotrophin brain-derived neutrophic factor (BDNF) is required for the appropriate development of the central respiratory network, a neuronal complex in the brainstem of vital importance to sustaining life. The pontine Kölliker-Fuse nucleus (KFN) is a fundamental component of this circuitry with strong implications in the pre- and postnatal breathing control. This study provides detailed account for the cytoarchitecture, the physiology and the ...

  17. Neuromedin U receptor 2 knockdown in the paraventricular nucleus modifies behavioral responses to obesogenic high-fat food and leads to increased body weight

    OpenAIRE

    Benzon, Caitlin R.; Johnson, Sarah B; McCue, David L.; Li, Dingge; Green, Thomas A; Hommel, Jonathan D.

    2013-01-01

    Neuromedin U (NMU) is a highly conserved neuropeptide which regulates food intake and body weight. Transgenic mice lacking NMU are hyperphagic and obese, making NMU a novel target for understanding and treating obesity. Neuromedin U receptor 2 (NMUR2) is a high-affinity receptor for NMU found in discrete regions of the central nervous system, in particular the paraventricular nucleus of the hypothalamus (PVN), where it may be responsible for mediating the anorectic effects of NMU. We hypothes...

  18. Modulatory Effect of Subthalamic Nucleus on the Development of Fatigue During Exhausting Exercise: An in Vivo Electrophysiological and Microdialysis Study in Rats

    OpenAIRE

    Dalei Wang; Xiaoli Liu; Decai Qiao

    2012-01-01

    The purpose of the study was to investigate the modulatory effect of changes of subthalamic nucleus (STN) activity on the development of central fatigue during exhausting exercise, and reveal the possible mechanism that might affect STN activity from the perspective of neurotransmitters. Rats were randomly divided into electrophysiology and microdialysis study groups. For electrophysiological study, electrical activity in sensorimotor cortex and STN were simultaneously recorded before, during...

  19. To centralize or not to centralize?

    OpenAIRE

    Campbell, Andrew; Kunisch, Sven; Müller-Stewens, Günter

    2011-01-01

    The CEO's dilemma-were the gains of centralization worth the pain it could cause?-is a perennial one. Business leaders dating back at least to Alfred Sloan, who laid out GM's influential philosophy of decentralization in a series of memos during the 1920s, have recognized that badly judged centralization can stifle initiative, constrain the ability to tailor products and services locally, and burden business divisions with high costs and poor service.1 Insufficient centralization can deny bus...

  20. Global optical potential for nucleus-nucleus systems from 50 MeV/u to 400 MeV/u

    CERN Document Server

    Furumoto, T; Takashina, M; Yamamoto, Y; Sakuragi, Y; 10.1103/PhysRevC.85.044607

    2012-01-01

    We present a new global optical potential (GOP) for nucleus-nucleus systems, including neutron-rich and proton-rich isotopes, in the energy range of $50 \\sim 400$ MeV/u. The GOP is derived from the microscopic folding model with the complex $G$-matrix interaction CEG07 and the global density presented by S{\\~ a}o Paulo group. The folding model well accounts for realistic complex optical potentials of nucleus-nucleus systems and reproduces the existing elastic scattering data for stable heavy-ion projectiles at incident energies above 50 MeV/u. We then calculate the folding-model potentials (FMPs) for projectiles of even-even isotopes, $^{8-22}$C, $^{12-24}$O, $^{16-38}$Ne, $^{20-40}$Mg, $^{22-48}$Si, $^{26-52}$S, $^{30-62}$Ar, and $^{34-70}$Ca, scattered by stable target nuclei of $^{12}$C, $^{16}$O, $^{28}$Si, $^{40}$Ca $^{58}$Ni, $^{90}$Zr, $^{120}$Sn, and $^{208}$Pb at the incident energy of 50, 60, 70, 80, 100, 120, 140, 160, 180, 200, 250, 300, 350, and 400 MeV/u. The calculated FMP is represented, with ...