WorldWideScience

Sample records for central japan response

  1. Central bank capital, financial strength, and the Bank of Japan

    OpenAIRE

    Thomas F. Cargill

    2006-01-01

    This Economic Letter addresses central bank capital and financial strength in the context of Bank of Japan policy (Cargill 2005). Specifically, it reviews general considerations about central bank capital and financial strength, discusses recent Bank of Japan policy in the context of capital structure, evaluates the Bank of Japan's concern in the context of the broader issue of central bank independence, and draws some lessons from recent Bank of Japan policy.

  2. Response to the Chernobyl accident in Japan

    International Nuclear Information System (INIS)

    Anon.

    1986-01-01

    The worst nuclear accident in history happened at No.4 unit of the Chernobyl Atomic Power Station in USSR. Since the Chernobyl accident, a number of measures have been introduced in many countries, including the reconsideration of programs for construction and operation of nuclear power plants. In Japan, the press and television first reported the accident on April 29. The next day, all the relevant governmental agencies began to collect and analyze information in order to prepare possible countermeasures. The Nuclear Safety Commission issued a statement covering three points: 1) the radioactive substances released by the accident will have virtually no influence on the health of people in Japan, 2) a Special Committee on the Chernobyl Atomic Power Station Accident will be established, and 3) the Soviet government must provide all detailed information about the accident as soon as it is available. On April 30, the Committee on Radioactivity decided to increase radioactivity observations by the Science and Technology Agency, the Defence Agency, and the Meteorological Agency. On the same day, the Ministry of International Trade and Industry set up a survey committee for the Chernobyl accident with the responsibility of collecting and analyzing information about the accident. A review is also made in this article as to how the Japanese media reported the accident and how people reacted on reading the newspapers and watching TV on the accident. (Nogami, K.)

  3. Semiplanus (Productida, Brachiopoda) from the Carboniferous limestone of Kotaki, Niigata Prefecture, central Japan

    OpenAIRE

    Ibaraki, Yousuke; Sato, Kiichi

    2013-01-01

    An Early Carboniferous large–sized productid brachiopod species, Semiplanus semiplanus (Schwetzow, 1922), is described from the Tsuchikurazawa Limestone (upper Visean–Serpukhovian), a limestone block within a Permian accretionary complex, distributed in the Kotaki area, Itoigawa City, Niigata Prefecture, central Japan. This is the first record of Semipanus species from Japan.

  4. Toward the responsible innovation with nanotechnology in Japan: our scope

    Energy Technology Data Exchange (ETDEWEB)

    Ishizu, Saori, E-mail: ishizu-saori@aist.go.jp; Sekiya, Mizuki [National Institute of Advanced Industrial Science and Technology (AIST), Technology Information Department (Japan); Ishibashi, Ken-ichi [Sony Corporation (Japan); Negami, Yumi [Trade and Industry (METI), Ministry of Economy (Japan); Ata, Masafumi [National Institute of Advanced Industrial Science and Technology (AIST), Technology Information Department (Japan)

    2008-02-15

    The societal impacts of nanotechnology have attracted growing attention in the United States and Europe in recent years. In Japan, the National Institute of Advanced Industrial Science and Technology (Technology Information Department) has played a central role in promoting discussions on this topic by collecting information from Japan and overseas, creating a network of the interested parties, and providing a forum for discussion. This paper presents a summary of recent activities in Japan relating to the societal impacts of nanotechnology, fro the launch of the 'Nanotechnology and Society' open forum (August 2004) until the 'Nanotechnology Debate' discussion forum (February 2007), and outlines the policy recommendations that came out of a project entitled 'Research on Facilitation of Public Acceptance of Nanotechnology' (March 2006)

  5. Toward the responsible innovation with nanotechnology in Japan: our scope

    International Nuclear Information System (INIS)

    Ishizu, Saori; Sekiya, Mizuki; Ishibashi, Ken-ichi; Negami, Yumi; Ata, Masafumi

    2008-01-01

    The societal impacts of nanotechnology have attracted growing attention in the United States and Europe in recent years. In Japan, the National Institute of Advanced Industrial Science and Technology (Technology Information Department) has played a central role in promoting discussions on this topic by collecting information from Japan and overseas, creating a network of the interested parties, and providing a forum for discussion. This paper presents a summary of recent activities in Japan relating to the societal impacts of nanotechnology, fro the launch of the 'Nanotechnology and Society' open forum (August 2004) until the 'Nanotechnology Debate' discussion forum (February 2007), and outlines the policy recommendations that came out of a project entitled 'Research on Facilitation of Public Acceptance of Nanotechnology' (March 2006)

  6. The stock market performance of the central banks of Belgium and Japan

    NARCIS (Netherlands)

    Kabir, Mohammed Rezaul; Goldberg, Lawrence G.

    2002-01-01

    Most central banks issue stock that is held by the government and/or commercial banks and is not tradable. In contrast, stocks of the central banks of Belgium and Japan are traded on the Brussels and Tokyo stock exchanges. The purpose of the paper is to examine this unique phenomenon of stock market

  7. China's air pollution and Japan's response to it

    International Nuclear Information System (INIS)

    Matsuura, S.

    1995-01-01

    Long-range transport of air pollutants has been a serious global environment problem. Japan's Central Research Institute of Electric Power Industry (CRIEPI) researchers are investigating the possibility of acid rain from China. So far, the acid rain that has appeared in Japan has not had a significant effect. However, because of the high economic growth projected for the coming years in China, acidic fallout from that country is likely to cause serious damage there and in Japan as well. China is one of the largest coal users in the world. One of the biggest factors making air quality worse is the lack of appropriate technologies. Although Japanese desulfurization technologies are well advanced, they cannot be directly applied to stationary pollution sources in China, because of their cost. Japan has sophisticated technologies, but lacks experience in and knowledge of alternative, intermediate, and low-technology solutions. Given this, Japan may attempt to buy pollution control technology equipment from the United States, which provides a wider range of desulfurization technologies, as a part of the Official Development Assistance program. At the same time, international support that includes the establishment of additional global environmental monitoring stations in China are also necessary

  8. Japan

    DEFF Research Database (Denmark)

    Hansen, Annette Skovsted

    2013-01-01

    I 1500- og 1600-tallet dannedes tidligt moderne stater i Europa, men samtidig eksisterede der ligeså avancerede statsdannelser uden for Europa, bl.a. i Kina, Indien og Japan. I det følgende ser vi nærmere på dannelsen af den moderne stat i Japan. Hvorfor blev Japan aldrig en europæisk koloni......? Hvordan havde japanske magthavere igennem 300 år forberedt Japan og de mennesker, der boede på de japanske øer, til at kunne udvikle en nation, der skulle blive den stærkeste og rigeste i Asien i mere end 100 år? Hvem bestemte i Japan? Kejseren eller shogunen?...

  9. Flora and vegetation in Mikazukiike-Awara moor in northern Nagano prefecture, central Japan.

    OpenAIRE

    井田, 秀行; 湯本, 茂; 湯本, 静江

    2003-01-01

    Flora and vegetation were investigated in Mikazukiike-Awara moor in northern Nagano prefecture, central Japan. The vegetation was chiefly characterized by the Sphagnum-sedge community. We recorded 242 species of vascular plants and 4 sphagnum species in this area. Population of some Liliaceae and Orchidaceae species have decreased over the past 12 years. It may be caused by drought associated with human impacts. Additionally, conservation of peripheral environments (e.g. secondary beech fores...

  10. Additional Gigantoproductus species from the upper Visean-Namurian limestone of Kotaki, central Japan

    OpenAIRE

    Ibaraki, Yousuke; Tazawa, Jun-ichi; Nakamura, Yukio

    2010-01-01

    A large productid brachiopod species, Gigantoproductus aurita (Bolkhovitinova, 1938), is described from the Tsuchikurazawa Limestone (upper Visean-Namurian), a large limestone block within a Permian accretionary complex of Kotaki, Itoigawa City, Niigata Prefecture, central Japan. This is the fourth described Gigantoproductus species from the Tsuchikurazawa Limestone. The range of G. aurita may extend to late Visean on the basis of the previous fossil records of the limestone.

  11. Neotectonics of central Japan and Izu-Bonin arc. Chuo Nippon no neotectonics to Izu Ogasawara ko

    Energy Technology Data Exchange (ETDEWEB)

    Takeuchi, A. (Toyama Univ., Toyama (Japan). College of Liberal Arts)

    1991-08-25

    Central Japan is the boundary region among the Northeast Japan arc (NEJ), which was parted from the Honshu arc accompanying the basin in the Japan sea area and the bending of Japan Islands, the Southwest Japan arc (SWJ) and the end of the Izu-Bonin arc (IOA), and involves the specific volcanic activity. In this report, the geohistory of the Late Cainozoic era in the central Japan was re-arranged and the neotectonics of the central Japan was tried to reorganize. Especially from a viewpoint that the central Japan is a juncture between the north end of the volcanic arc IOA (Fuji, Norikura and Hakusan volcanic belts) and the southwest end of the volcanic arc NEJ (Nasu and Chokai volcanic belts), the relation between the volcanic activity and tectonics from the Pliocene to Pleistocene has been mainly handled in the Hida region east of the Hakusan and in the northern Fossa Magna region. In addition to it, the tectonics was pointed out to be an indication of mechanical jointing state with IOA. Then the results of IOA drilling according to ODP, Leg 129 were referred as well, in order to compare with the transition of more typical volcanic activity in IOA. 61 refs., 4 figs.

  12. Japan

    International Nuclear Information System (INIS)

    Matsui, T.

    1975-01-01

    A report is given on the basic research and development in food irradiation in Japan. Two new irradiation facilities are extensively described. Basic research is performed in radiation chemistry of fruits, potatoes, fish products, meat products and model systems. Microbiological research is concerned with Clostridium botulinum and radicidation and radurization studies, as well as effects of combination treatment on Micrococcus radiodurans. Radiation treatment of grain, frutis, vegetables, potatoes, fish, meat and meat products and other commodities is performed. Wholesomeness studies are dealing with the nutritional value and animal feeding studies are carried out with irradiated potatoes, onions, rice, wheat, and sausages. Two short chapters are concerned with legislation and marketing. (MG) [de

  13. Measurement of the 36Cl deposition flux in central Japan: natural background levels and seasonal variability

    International Nuclear Information System (INIS)

    Tosaki, Yuki; Tase, Norio; Sasa, Kimikazu; Takahashi, Tsutomu; Nagashima, Yasuo

    2012-01-01

    Essential parameters for the applications of 36 Cl as a tracer in groundwater studies include the initial 36 Cl/Cl ratio, at the time of recharge, and/or the natural background deposition flux of 36 Cl in the recharge area. To facilitate the hydrological use of 36 Cl in central Japan, this study aimed to obtain a precise estimate of the long-term average local 36 Cl flux and to characterize its seasonal variability. The 36 Cl in precipitation was continuously monitored in Tsukuba, central Japan over a period of >5 years. The 36 Cl flux showed a clear seasonal variation with an annual peak during the spring, which was attributed to the seasonal variability of tropopause height. The long-term average 36 Cl flux (32 ± 2 atoms m −2 s −1 ), estimated from the measured data, was consistent with the prediction from the 36 Cl latitudinal fallout model scaled using the global mean production rate of 20 atoms m −2 s −1 . The initial 36 Cl/Cl ratio was estimated to be (41 ± 6) × 10 −15 , which is similar to that of pre-bomb groundwater in the Tsukuba Upland. An observation period covering an 11-year solar cycle would yield more accurate estimates of the values, given the increased 36 Cl flux during the solar minimum. - Highlights: ► We monitored 36 Cl in precipitation in central Japan over a period of >5 years. ► The 36 Cl flux varied seasonally, with a peak in spring. ► The long-term average 36 Cl flux and the initial 36 Cl/Cl ratio were 32 ± 2 atoms m −2 s −1 and (41 ± 6) × 10 −15 , respectively. ► An observation period covering an 11-year solar cycle would yield more accurate estimates of the values, given the increased 36 Cl flux during the solar minimum.

  14. Japan

    International Nuclear Information System (INIS)

    Huttner, Kevin; Suzuki, Tatsujiro

    1987-01-01

    The Japanese nuclear power programme began with reactors imported from the United States. A natural uranium heavy water reactor using domestic materials was started in 1958. Subsequent progress was with light water reactors imported from the United States. Domestic reactor development was of a fast breeder reactor and an advanced thermal reactor. By March 1986 there were 32 commercial power plants in operation which produced approximately 23% of the electricity consumed in Japan. Ten more are under construction and six more are planned. Their location and comparative generating cost are tabulated. Energy demand and targets for nuclear power generation are discussed. The FBR advanced thermal reactor and high temperature reactor programmes are summarized. The Japanese nuclear fuel cycle - uranium prospecting, enrichment, reprocessing, the development of mixed oxide fuels, thermal recycling and radioactive waste management is also discussed. (U.K.)

  15. Large floods and climatic change during the Holocene on the Ara River, Central Japan

    Science.gov (United States)

    Grossman, Michael J.

    2001-07-01

    A reconstruction of part of the Holocene large flood record for the Ara River in central Japan is presented. Maximum intermediate gravel-size dimensions of terrace and modern floodplain gravels were measured along an 18-km reach of the river and were used in tractive force equations to estimate minimum competent flood depths. Results suggest that the magnitudes of large floods on the Ara River have varied in a non-random fashion since the end of the last glacial period. Large floods with greater magnitudes occurred during the warming period of the post-glacial and the warmer early to middle Holocene (to ˜5500 years BP). A shift in the magnitudes of large floods occurred ˜5500-5000 years BP. From this time, during the cooler middle to late Holocene, large floods generally had lower magnitudes. In the modern period, large flood magnitudes are the largest in the data set. As typhoons are the main cause of large floods on the Ara River in the modern record, the variation in large flood magnitudes suggests that the incidence of typhoon visits to the central Japan changed as the climate changed during the Holocene. Further, significant dates in the large flood record on the Ara River correspond to significant dates in Europe and the USA.

  16. Circumstances surrounding death and nursing difficulties with end-of-life care for individuals with ALS in central Japan.

    Science.gov (United States)

    Ushikubo, Mitsuko; Okamoto, Koichi

    2012-11-01

    This study aimed to clarify the circumstances surrounding death for people with amyotrophic lateral sclerosis (ALS) in Japan and difficulties in providing home-care end-of-life nursing for these individuals. A questionnaire was mailed to the directors of 709 home-care nursing agencies located in central Japan. Of 232 questionnaires returned (response rate 32.8%), 49 reported treating someone with ALS. Overall, 31% of these patients died at home, whereas 63% were admitted to hospital from a few days to months preceding death. Respiratory insufficiency was identified as the cause of death in 73% of cases, 45% of the deaths were sudden, and 27% of the deaths involved CO2 narcosis. Analysis of the reported nursing difficulties resulted in five categories: lack of adaptation to the disease or disease progression by the patient and/or their family, involvement with family, how to select/deliver care, decision-making and communication, and poor collaboration with other practitioners. Family care and family education are important to supporting the end-of-life process for people with ALS. Use of advance directives and collaboration with other related practitioners are recommended to enhance communication linked to psychological care and informed consent.

  17. Volcanism and Tectonics of the Central Deep Basin, Sea of Japan

    Science.gov (United States)

    Lelikov, E. P.; Emelyanova, T. A.; Pugachev, A. A.

    2018-01-01

    The paper presents the results of a study on the geomorphic structure, tectonic setting, and volcanism of the volcanoes and volcanic ridges in the deep Central Basin of the Sea of Japan. The ridges rise 500-600 m above the acoustic basement of the basin. These ridges were formed on fragments of thinned continental crust along deep faults submeridionally crossing the Central Basin and the adjacent continental part of the Primorye. The morphostructures of the basin began to submerge below sea level in the Middle Miocene and reached their contemporary positions in the Pliocene. Volcanism in the Central Basin occurred mostly in the Middle Miocene-Pliocene and formed marginal-sea basaltoids with OIB (ocean island basalt) geochemical signatures indicating the lower-mantle plume origin of these rocks. The OIB signatures of basaltoids tend to be expressed better in the eastern part of the Central Basin, where juvenile oceanic crust has developed. The genesis of this crust is probably related to rising and melting of the Pacific superplume apophyse.

  18. Tectonic implications of a paleomagnetic direction obtained from a Miocene dike swarm in central Honshu, Japan

    Science.gov (United States)

    Hoshi, H.; Sugisaki, Y.

    2017-12-01

    Central Honshu of Japan is an ideal field for the study of crustal deformation related to arc-arc collision. In this study we obtained rock magnetic and paleomagnetic results from early Miocene igneous rocks in central Honshu in order to examine rotational deformation caused by the collision of the Izu-Bonin-Mariana (IBM) arc with central Honshu. In Takane of the Hida region, gabbro intrusions and older sedimentary rocks are intruded by numerous andesitic dikes that comprise a parallel dike swarm. The dikes formed under two different normal-faulting paleostress conditions, which were suggested using a method of clustering dike orientations. Cross-cutting relationships indicate that the two paleostress conditions existed during the same period. More than 240 oriented cores were taken at 38 sites in two localities for magnetic study. The andesites and gabbros generally have magnetite, and some andesites also contain pyrrhotite. The magnetite records easterly deflected remanent magnetization directions of dual polarities that pass the reversals test. Positive baked contact tests at two sites demonstrate that the easterly deflected direction is a thermoremanent magnetization acquired at the time of intrusion. The overall in situ (i.e., in geographic coordinates) mean direction for andesitic dikes is judged to be highly reliable, although there are two possible scenarios for explaining the easterly deflection: (1) clockwise rotation and (2) tilting to the northwest. We prefer the former scenario and conclude that 45° clockwise rotation occurred in Takane with respect to the North China Block of the Asian continent. This rotation must represent the clockwise rotation of entire Southwest Japan during the opening period of the Japan Sea. Very little difference is observed between the amount of the easterly deflection in Takane and those in the Tokai and Hokuriku regions, indicating no significant relative rotation. Thus, the crust beneath Takane has not suffered rotation

  19. Country report from Japan: Activities of NIRS as a central reference laboratory

    International Nuclear Information System (INIS)

    Kawamura, H.; Shiraishi, K.; Ozawa, K.; Arae, H.; Yukawa, M.

    2000-01-01

    As agreed upon at the Project Formulation Meeting and the First Research Co-ordination Meeting, functions of the central reference laboratory (CRL) in assistance to the Agency were assigned to National Institute of Radiological Sciences (NIRS). Therefore, we have been making utmost efforts, aside from our own research activities concerning the current CRP, to cope with the following assignments, in which we are supported through the Science and Technology Agency of Japan. There was some delay in the progress for the planned distribution of three Reference Materials for internal quality control (QC) and preparation in Japan of the reference diet material of an Asian composition. However, training of fellow research workers of the CRP and associated co-operation that were requested by some of the participants, were satisfactorily carried out. During the next 18 months, we foresee (a) analysis of '10% samples' sent by the participants for external QC, (b) backup analysis of some number of samples for the first priority elements for some participants, and (c) distribution of the Japanese reference diet material when it is prepared, to accelerate progress of the CRP as originally planned. We are putting an emphasis on the strong will to completing the Project to provide researchers worldwide with essential data for metabolism of the elements of importance in internal dosimetry and Reference Man. It should be noted, however, the CRL is moving from its present location to the Chiba campus, about 130 km to the south by car, sometime during 1999. Due to the relocation process, our analytical work will probably be interrupted for a month or two

  20. Resistivity characterisation of Hakone volcano, Central Japan, by three-dimensional magnetotelluric inversion

    Science.gov (United States)

    Yoshimura, Ryokei; Ogawa, Yasuo; Yukutake, Yohei; Kanda, Wataru; Komori, Shogo; Hase, Hideaki; Goto, Tada-nori; Honda, Ryou; Harada, Masatake; Yamazaki, Tomoya; Kamo, Masato; Kawasaki, Shingo; Higa, Tetsuya; Suzuki, Takeshi; Yasuda, Yojiro; Tani, Masanori; Usui, Yoshiya

    2018-04-01

    On 29 June 2015, a small phreatic eruption occurred at Hakone volcano, Central Japan, forming several vents in the Owakudani geothermal area on the northern slope of the central cones. Intense earthquake swarm activity and geodetic signals corresponding to the 2015 eruption were also observed within the Hakone caldera. To complement these observations and to characterise the shallow resistivity structure of Hakone caldera, we carried out a three-dimensional inversion of magnetotelluric measurement data acquired at 64 sites across the region. We utilised an unstructured tetrahedral mesh for the inversion code of the edge-based finite element method to account for the steep topography of the region during the inversion process. The main features of the best-fit three-dimensional model are a bell-shaped conductor, the bottom of which shows good agreement with the upper limit of seismicity, beneath the central cones and the Owakudani geothermal area, and several buried bowl-shaped conductive zones beneath the Gora and Kojiri areas. We infer that the main bell-shaped conductor represents a hydrothermally altered zone that acts as a cap or seal to resist the upwelling of volcanic fluids. Enhanced volcanic activity may cause volcanic fluids to pass through the resistive body surrounded by the altered zone and thus promote brittle failure within the resistive body. The overlapping locations of the bowl-shaped conductors, the buried caldera structures and the presence of sodium-chloride-rich hot springs indicate that the conductors represent porous media saturated by high-salinity hot spring waters. The linear clusters of earthquake swarms beneath the Kojiri area may indicate several weak zones that formed due to these structural contrasts.[Figure not available: see fulltext.

  1. [Germinoma responsible for central diabetes insipidus].

    Science.gov (United States)

    Bakoto, N; Strivay, M

    2009-01-01

    We report the case of a 20-year-old woman who presented with sudden onset of polydipsia and polyuria. A diagnosis of diabetes insipidus was confirmed and the MRI showed a pituitary stalk enlargement. The patient was treated with Minirin. Two years later, she developed a panhypopituitarism. The MRI showed an intrasellar mass with an enlargement of the pituitary gland. A biopsy confirmed a germinoma. The patient was treated with radiotherapy with a partial response as only a part of the mass disappeared. This case highlights the importance of the clinical and radiological follow-up of central diabetes insipidus, especially when it is of unknown origin. The differential diagnosis will be reviewed.

  2. Modelling psychological responses to the Great East Japan earthquake and nuclear incident.

    Science.gov (United States)

    Goodwin, Robin; Takahashi, Masahito; Sun, Shaojing; Gaines, Stanley O

    2012-01-01

    The Great East Japan (Tōhoku/Kanto) earthquake of March 2011 was followed by a major tsunami and nuclear incident. Several previous studies have suggested a number of psychological responses to such disasters. However, few previous studies have modelled individual differences in the risk perceptions of major events, or the implications of these perceptions for relevant behaviours. We conducted a survey specifically examining responses to the Great Japan earthquake and nuclear incident, with data collected 11-13 weeks following these events. 844 young respondents completed a questionnaire in three regions of Japan; Miyagi (close to the earthquake and leaking nuclear plants), Tokyo/Chiba (approximately 220 km from the nuclear plants), and Western Japan (Yamaguchi and Nagasaki, some 1000 km from the plants). Results indicated significant regional differences in risk perception, with greater concern over earthquake risks in Tokyo than in Miyagi or Western Japan. Structural equation analyses showed that shared normative concerns about earthquake and nuclear risks, conservation values, lack of trust in governmental advice about the nuclear hazard, and poor personal control over the nuclear incident were positively correlated with perceived earthquake and nuclear risks. These risk perceptions further predicted specific outcomes (e.g. modifying homes, avoiding going outside, contemplating leaving Japan). The strength and significance of these pathways varied by region. Mental health and practical implications of these findings are discussed in the light of the continuing uncertainties in Japan following the March 2011 events.

  3. Modelling psychological responses to the Great East Japan earthquake and nuclear incident.

    Directory of Open Access Journals (Sweden)

    Robin Goodwin

    Full Text Available The Great East Japan (Tōhoku/Kanto earthquake of March 2011 was followed by a major tsunami and nuclear incident. Several previous studies have suggested a number of psychological responses to such disasters. However, few previous studies have modelled individual differences in the risk perceptions of major events, or the implications of these perceptions for relevant behaviours. We conducted a survey specifically examining responses to the Great Japan earthquake and nuclear incident, with data collected 11-13 weeks following these events. 844 young respondents completed a questionnaire in three regions of Japan; Miyagi (close to the earthquake and leaking nuclear plants, Tokyo/Chiba (approximately 220 km from the nuclear plants, and Western Japan (Yamaguchi and Nagasaki, some 1000 km from the plants. Results indicated significant regional differences in risk perception, with greater concern over earthquake risks in Tokyo than in Miyagi or Western Japan. Structural equation analyses showed that shared normative concerns about earthquake and nuclear risks, conservation values, lack of trust in governmental advice about the nuclear hazard, and poor personal control over the nuclear incident were positively correlated with perceived earthquake and nuclear risks. These risk perceptions further predicted specific outcomes (e.g. modifying homes, avoiding going outside, contemplating leaving Japan. The strength and significance of these pathways varied by region. Mental health and practical implications of these findings are discussed in the light of the continuing uncertainties in Japan following the March 2011 events.

  4. Erosion and sedimentation during the September 2015 flooding of the Kinu River, central Japan.

    Science.gov (United States)

    Dan Matsumoto; Sawai, Yuki; Yamada, Masaki; Namegaya, Yuichi; Shinozaki, Tetsuya; Takeda, Daisuke; Fujino, Shigehiro; Tanigawa, Koichiro; Nakamura, Atsunori; Pilarczyk, Jessica E

    2016-09-28

    Erosional and sedimentary features associated with flooding have been documented in both modern and past cases. However, only a few studies have demonstrated the relationship between these features and the corresponding hydraulic conditions that produced them, making it difficult to evaluate the magnitude of paleo-flooding. This study describes the characteristics associated with inundation depth and flow direction, as well as the erosional and sedimentary features resulting from the disastrous flooding of the Kinu River, central Japan, in September 2015. Water levels rose rapidly due to heavy rainfall that eventually overtopped, and subsequently breached, a levee in Joso City, causing destructive flooding on the surrounding floodplain. Distinctive erosional features are found next to the breached levee, while depositional features, such as a sandy crevasse-splay deposit are found further away from the breach. The deposit can be divided into three units based on sedimentary facies. The vertical and lateral changes of these sedimentary facies may be the result of temporal and spatial changes associated with flow during the single flooding event. These observations and quantitative data provide information that can be used to reveal the paleohydrology of flood deposits in the stratigraphic record, leading to improved mitigation of future flooding disasters.

  5. Isotopic studies of marbles in the Sanbagawa metamorphic terrain, central Shikoku, Japan

    International Nuclear Information System (INIS)

    Wada, Hideki; Enami, Masaki; Yanagi, Takeru.

    1984-01-01

    Carbon, oxygen and strontium isotopic studies were carried out on marbles occurring in crystalline schists and epidote amphibolites of the Sanbagawa metamorphic terrain, central Shikoku, Japan, in order to estimate metamorphic temperatures and to elucidate their origin. Carbon isotopic fractionation between calcite and graphite shows the metamorphic temperature of 460 deg C at the transitional part between the garnet and albite-biotite zones. Marbles are isotopically classified into two groups. (1) some marbles in epidote amphibolite masses show characteristically negative delta 13 C values and low 87 Sr/ 86 Sr ratios. These marbles are interpreted as have been derived from magmatic or deep-seated carbonates. (2) marbles collected from the crystalline schists and from the marginal part of epidote amphibolite masses, have high 87 Sr/ 86 Sr ratios and delta 13 C values similar to those of typical sedimentary carbonates. They were probably derived from sedimentary carbonates and/or carbonates re-equilibrated with metamorphic fluid segregated from crystalline schists during the Sanbagawa metamorphism. (author)

  6. A comparative study of golf industry between Yangtze River Delta, China and Central Japan

    Science.gov (United States)

    Yang, Yangfan; Jin, Pingbin; Gong, Huiwen

    2018-03-01

    As a competition event of the 2016 Olympic Game, golf sport has aroused great attention around the world. And the Yangtze River Delta(YRD) in China, has already got certain basis and qualifications of developing golf industry, but somehow far from meeting the great potential demand of the market. This research selects the Yangtze River Delta (YRD) and Central Japan (CJ), which are indifferent golf developing stages, as the objectives. Comparative studies are being carried out with an aim of revealing the discrepancies of golf industry in selected regions. The correlations between golf industry and regional economic developing level have been explored as well. Mainly based on a geographical perspective, this research presents an initial effort to combine approaches of setting comparative indexes and spatial analysis, so that golf industry of selected regions will be compared in all directions. The results reveal that great gaps exist in YRD and CJ in terms of golf construction, service, and golf consumption. Problems in developing golf industry in YRD are identified based on the empirical results. A long-term golf development in YRD that deviating from the realistic demand is attributed to both government policies and the operational principles that the market subjects hold. Based on a comparative empirical study, suggestions relating to the government as well as the market players are put forward, with an aim of guiding the golf industry to develop in a sustainable way.

  7. Seismomagnetic models for earthquakes in the eastern part of Izu Peninsula, Central Japan

    Directory of Open Access Journals (Sweden)

    Y. Ishikawa

    1997-06-01

    Full Text Available Seismomagnetic changes accompanied by four damaging earthquakes are explained by the piezomagnetic effect observed in the eastern part of Izu Peninsula, Central Japan. Most of the data were obtained by repeat surveys. Although these data suffered electric railway noise, significant magnetic changes were detected at points close to earthquake faults. Coseismic changes can be well interpreted by piezomagnetic models in the case of the 1978 Near Izu-Oshima (M 7.0 and the 1980 East Off Izu Peninsula (M 6.7 earthquakes. A large total intensity change up to 5 nT was observed at a survey point almost above the epicenter of the 1976 Kawazu (M 5.4 earthquake. This change is not explained by a single fault model; a 2-segment fault is suggested. Remarkable precursory and coseismic changes in the total force intensity were observed at KWZ station along with the 1978 Higashi-Izu (M 4.9 earthquake. KWZ station is located very close to a buried subsidiary fault of the M 7.0 Near Izu-Oshima earthquake, which moved aseismically at the time of the M 7.0 quake. The precursory magnetic change to the M 4.9 quake is ascribed to aseismic faulting of this buried fault, while the coseismic rebound to enlargement of the slipping surface at the time of M 4.9 quake. This implies that we observed the formation process of the earthquake nucleation zone via the magnetic field.

  8. Characteristics of intrafault materials within the AtotsugawaF fault of central Japan, (2)

    International Nuclear Information System (INIS)

    Kanaori, Yuji; Miyakoshi, Katsuyoshi; Inohara, Yoshiki; Satake, Yoshinori

    1983-01-01

    Mineralogical and geochemical studies carried out on intrafault materials collected at two outcrops of the Atotsugawa fault of Central Japan, which had been described in detail in the previous paper. A sample of intrafault materials was divided into four fractions of 2μ>, 2-7μ, 74-250μ and 250μ fraction is including more amount of montmorillonite, illite and chlorite and contrastively less amount of quartz, feldspar and calcite than the other three fractions. The geochemical composition of the 2μ> fraction is rich in Al 2 O 3 , MgO, K 2 O and total H 2 O and poor in SiO 2 , CaO, Na 2 O and CO 2 comparing with those of the other three fractions. It is disclosed that the mineralogy, geochemical compositions and grain size of the intrafault materials have close relationship one another and should be related to the formation process of the materials and the degree of their weathering or alteration. (author)

  9. Towards revitalization of the world economy: Japan responsible for four projects

    Energy Technology Data Exchange (ETDEWEB)

    Shaku, A

    1983-05-10

    A progress report by the Working Group on Technology, Growth, and Employment not only stresses the importance of science and technology, but analyzes their employment, cultural, and other effects. Japan's responsibility in four areas covers safety research on light water reactors, photovoltaic energy for direct conversion into electricity, the use of photosynthesis processes to produce energy, and the introduction of advanced robotics. Japan's goal is to support international cooperation in these and the remaining 18 projects. 2 tables. (DCK)

  10. Technological solution for the protection of the environment (in the Central Research Inst. of Electric Power Industry, Tokyo, Japan)

    International Nuclear Information System (INIS)

    Glamochanin, Vlastimir

    1997-01-01

    As we approach the 21 century, the world finds itself confronting challenges regarding global-scale issues: economic development, the use of energy and natural resources, and environmental preservation. Moreover, these issues do not exist in a vacuum; they are all interrelated. They exert delicate effects on each other and can not be considered separately. If we continue as we have in the past, the earth will face an unprecedented crisis in the middle of coming century, in conjunction with the population explosion. (Susumu Yoda, President of the Central Research Inst. of Electric Power Industry, Tokyo, Japan). This paper presents a brief review of the research policy of the Japan Central Research Inst. of Electric Power Industry, regarding environmental preservation

  11. Paleovegetation reconstruction of fossil forests dominated by Metasequoia and Glyptostrobus from the late Pliocene Kobiwako Group, central Japan

    OpenAIRE

    CHIYOMI, YAMAKAWA; ARATA, MOMOHARA; TOMOO, NUNOTANI; MIDORI, MATSUMOTO; YASUYUKI, WATANO; Lake Biwa Museum; Graduate School of Horticulture, Chiba University; Lake Biwa Museum; Graduate School of Science, Chiba University; Graduate School of Science, Chiba University

    2008-01-01

    A late Pliocene (1.8-1.9 Ma) wetland fossil forest community that was dominated by Metasequoia and Glyptostrobus was reconstructed based on the species composition of the stumps and other plant macrofossil assemblages. The plant fossils were recovered from a fossil forest preserved in deposits of the Kobiwako Group that are exposed in the Echi River, Shiga Prefecture, central Japan. Fossil wood of Metasequoia and Glyptostrobus was distinguished based on anatomical characteristics. Apportionme...

  12. Introductory analysis of sustainable consumption and production : Factors of corporate social responsibility management in Japan

    OpenAIRE

    八木, 迪幸; 國部, 克彦

    2017-01-01

    As an introductory analysis of sustainable consumption and production, this paper examines what factors influence corporate social responsibility management in Japan. Following some underlying theories (management control system; the neo-institutional theory; performance measurement systems; the stakeholder theory; the resource dependence theory), this paper conducts empirical studies using firm-level data. The first three studies examine what factors encourage corporate social responsibility...

  13. Attenuation Tomography Based on Strong Motion Data: Case Study of Central Honshu Region, Japan

    Science.gov (United States)

    Kumar, Parveen; Joshi, A.; Verma, O. P.

    2013-12-01

    Three-dimensional frequency dependent S-wave quality factor (Qβ(f)) value for the central Honshu region of Japan has been determined in this paper using an algorithm based on inversion of strong motion data. The method of inversion for determination of three-dimensional attenuation coefficients is proposed by H ashida and S himazaki (J Phys Earth. 32, 299-316, 1984) and has been used and modified by J oshi (Curr Sci. 90, 581-585, 2006; Nat Hazards. 43, 129-146, 2007) and J oshi et al. (J. Seismol. 14, 247-272, 2010). Twenty-one earthquakes digitally recorded on strong motion stations of Kik-net network have been used in this work. The magnitude of these earthquake ranges from 3.1 to 4.2 and depth ranging from 5 to 20 km, respectively. The borehole data having high signal to noise ratio and minimum site effect is used in the present work. The attenuation structure is determined by dividing the entire area into twenty-five three-dimensional blocks of uniform thickness having different frequency-dependent shear wave quality factor. Shear wave quality factor values have been determined at frequencies of 2.5, 7.0 and 10 Hz from record in a rectangular grid defined by 35.4°N to 36.4°N and 137.2°E to 138.2°E. The obtained attenuation structure is compared with the available geological features in the region and comparison shows that the obtained structure is capable of resolving important tectonic features present in the area. The proposed attenuation structure is compared with the probabilistic seismic hazard map of the region and shows that it bears some remarkable similarity in the patterns seen in seismic hazard map.

  14. Susceptible conditions for debarking by deer in subalpine coniferous forests in central Japan

    Directory of Open Access Journals (Sweden)

    Hayato Iijima

    2015-12-01

    Full Text Available Background: Recently, deer have expanded their distribution to higher altitude ranges including subalpine forests. However, culling deer and construction of deer fence in subalpine forests are difficult because of steep slopes and complex topography. Thus it is necessary to clarify the factors which are associated with debarking by deer for the effective protection of subalpine forests. In this study, we examined which factors are associated with debarking by sika deer (Cervus nippon in subalpine coniferous forests. Methods: We conducted our survey in Minami-Alps National Park, central Japan. We established 24 10 m× 40 m plots and surveyed the occurrence of debarking on saplings >30 cm in height and 3 cm in DBH, as well as sapling density within each plot. Minimum distances to nearest grassland of plots were calculated (tentatively assuming grassland would attract deer and would cause high debarking pressure in the surrounding subalpine forests. Results: The mean percentage of debarked live saplings was higher than that of live trees. The mean percentage of debarked saplings which had already died was 81.6 %. Debarking of saplings increased with lower elevation, taller sapling size, and marginally increased near grassland. Sapling density was lower in plots with low basal area of conspecific trees near grassland and differed among species. Sapling density marginally decreased with decreasing elevation and increasing stand tree density. Debarking of trees was positively related to small DBH and low elevation, and marginally increased near grassland and differed among species. Conclusions: Our results suggest that tall saplings in subalpine forests of low elevation or near subalpine grassland were susceptible to debarking by deer and monitoring of these areas may permit the early detection of the impacts of deer in subalpine coniferous forests. Keywords: Abies, Cervus nippon, Debarking, Grassland, Picea, Sapling density, Subalpine region

  15. Temporal variations of atmospheric CO2 concentration in a temperate deciduous forest in central Japan

    International Nuclear Information System (INIS)

    Murayama, Shohei; Saigusa, Nobuko; Yamamoto, Susumu; Kondo, Hiroaki; Eguchi, Yozo; Chan, Douglas

    2003-01-01

    In order to examine the temporal variation of the atmospheric CO 2 concentration in a temperate deciduous forest, and its relationship with meteorological conditions, continuous measurements of CO 2 and meteorological parameters have been made since 1993 on a tower at Takayama in the central part of Japan. In addition to an average secular increase in atmospheric CO 2 of 1.8 ppm/yr, diurnal variation with a maximum during the night-time to early morning and a minimum in the afternoon is observed from late spring to early fall; the diurnal cycle is not so clearly observed in the remaining seasons of the year. A concentration difference between above and below the canopy, and its diurnal variation, can also be seen clearly in summer. Daily mean concentration data show a prominent seasonal cycle. The maximum and the minimum of the seasonal cycle occur in April and from mid August to mid September, respectively. Day-to-day changes in the diurnal cycle of CO 2 are highly dependent on the day-to-day variations in meteorological conditions. However, CO 2 variations on longer time scales (>10 d) appear to be linearly related to changes in respiration. At Takayama, variations in the 10-d standard deviation of daily mean CO 2 data and 10-d averaged respiration show distinct relationships with soil temperature during spring and fall seasons. In spring, respiration has a stronger exponential dependence on soil temperature than in fall. Interestingly, in summer when soil temperature becomes greater than about 15 deg C, biological respiration becomes more variable and independent of the soil temperature. Thus, at the Takayama site, the Q10 relationship is seasonally dependent, and does not represent well the biological respiration process when the soil temperature rises above 15 deg C

  16. A Facebook's Responses to the 2011 Triple Catastrophe in Japan

    DEFF Research Database (Denmark)

    Hansen, Annette Skovsted

    In this short paper, I will present an overview and analysis of the content of greetings posted to the Association of Overseas Technical Scholarships (AOTS) facebook group in the context of the global reach of the AOTS alumni network. In my investigation of how Japanese ODA policies and practices...... have engendered global networks, I have frequented the Association of Overseas Technical Scholarships (AOTS)' Facebook group. In the wake of the earthquake on March 11, 2011, many greetings came in from alumni who have within the last 50 years attended overseas training courses in Japan, which have...... been organized by AOTS and partially funded by Japanese ODA channelled through the MITI, later MeTI. In this short paper, I will try to present an overview of the content of the greetings and analyze the greetings in the context of the global reach of the AOTS alumni network....

  17. Reflections on the emergency preparations and responses of China to Fukushima nuclear accident in Japan

    International Nuclear Information System (INIS)

    Chen Xiaoqiu; Li Bing; Yu Shaoqing

    2012-01-01

    This paper reviewed the emergency response of Japan in Fukushima nuclear accident, provided and discussed the issues should be of concern on emergency preparedness and response in future: (1) modifying the existing emergency preparedness and response system; (2) consolidating the concept of emergency preparedness as the ultimate level of defense-in-depth; (3) promoting the emergency response decision-making support capabilities; (4) valuing the information opening of involving nuclear news and radiation environmental information. (authors)

  18. Recent Intermediate Depth Earthquakes in El Salvador, Central Mexico, Cascadia and South-West Japan

    Science.gov (United States)

    Lemoine, A.; Gardi, A.; Gutscher, M.; Madariaga, R.

    2001-12-01

    We studied occurence and source parameters of several recent intermediate depth earthquakes. We concentrated on the Mw=7.7 salvadorian earthquake which took place on January 13, 2001. It was a good example of the high seismic risk associated to such kind of events which occur closer to the coast than the interplate thrust events. The Salvadorian earthquake was an intermediate depth downdip extensional event which occured inside the downgoing Cocos plate, next to the downdip flexure where the dip increases sharply before the slab sinks more steeply. This location corresponds closely to the position of the Mw=5.7 1996 and Mw=7.3 1982 downdip extensional events. Several recent intermediate depth earthquakes occured in subduction zones exhibiting a ``flat slab'' geometry with three distinct flexural bends where flexural stress may be enhanced. The Mw=6.7 Geiyo event showed a downdip extensional mechanism with N-S striking nodal planes. This trend was highly oblique to the trench (Nankai Trough), yet consistent with westward steepening at the SW lateral termination of the SW Japan flat slab. The Mw=6.8 Olympia earthquake in the Cascadia subduction zone occured at the downdip termination of the Juan de Fuca slab, where plate dip increases from about 5o to over 30o. The N-S orientation of the focal planes, parallel to the trench indicated downdip extension. The location at the downdip flexure corresponds closely to the estimated positions of the 1949 M7.1 Olympia and 1965 M6.5 Seattle-Tacoma events. Between 1994 and 1999, in Central Mexico, an unusually high intermediate depth seismicity occured where several authors proposed a flat geometry for the Cocos plate. Seven events of magnitude between Mw=5.9 and Mw=7.1 occured. Three of them were downdip compressional and four where down-dip extensional. We can explain these earthquakes by flexural stresses at down-dip and lateral terminations of the supposed flat segment. Even if intermediate depth earthquakes occurence could

  19. Radiation response of the central nervous system

    International Nuclear Information System (INIS)

    Schultheiss, T.E.; Kun, L.E.; Ang, K.K.; Stephens, L.C.

    1995-01-01

    This report reviews the anatomical, pathophysiological, and clinical aspects of radiation injury to the central nervous system (CNS). Despite the lack of pathognomonic characteristics for CNS radiation lesions, demyelination and malacia are consistently the dominant morphological features of radiation myelopathy. In addition, cerebral atrophy is commonly observed in patients with neurological deficits related to chemotherapy and radiation, and neurocognitive deficits are associated with diffuse white matter changes. Clinical and experimental dose-response information have been evaluated and summarized into specific recommendations for the spinal cord and brain. The common spinal cord dose limit of 45 Gy in 22 to 25 fractions is conservative and can be relaxed if respecting this limit materially reduces the probability of tumor control. It is suggested that the 5% incidence of radiation myelopathy probably lies between 57 and 61 Gy to the spinal cord in the absence of dose modifying chemotherapy. A clinically detectable length effect for the spinal cord has not been observed. The effects of chemotherapy and altered fractionation are also discussed. Brain necrosis in adults is rarely noted below 60 Gy in conventional fractionation, with imaging and clinical changes being observed generally only above 50 Gy. However, neurocognitive effects are observed at lower doses, especially in children. A more pronounced volume effect is believed to exist in the brain than in the spinal cord. Tumor progression may be hard to distinguish from radiation and chemotherapy effects. Diffuse white matter injury can be attributed to radiation and associated with neurological deficits, but leukoencephalopathy is rarely observed in the absence of chemotherapy. Subjective, objective, management, and analytic (SOMA) parameters related to radiation spinal cord and brain injury have been developed and presented on ordinal scales

  20. Radiation response of the central nervous system

    International Nuclear Information System (INIS)

    Schultheiss, T.E.; Kun, L.E.; Stephens, L.C.

    1995-01-01

    This report reviews the anatomical, pathophysiological, and clinical aspects of radiation injury to the central nervous system (CNS). Despite the lack of pathoGyomonic characteristics for CNS radiation lesions, demyelination and malacia are consistently the dominant morphological features of radiation myelopathy. In addition, cerebral atrophy is commonly observed in patients with neurological deficits related to chemotherapy and radiation, and neurocognitive deficits are associated with diffuse white matter changes. Clinical and experimental dose-response information have been evaluated and summarized into specific recommendations for the spinal cord and brain. The common spinal cord dose limit of 45 Gn in 22 to 25 fractions is conservative and can be relaxed if respecting this limit materially reduces the probability of tumor control. It is suggested that the 5% incidence of radiation myelopathy probably lies between 57 and 61 Gy to the spinal cord in the absence of dose modifying chemotherapy. A clinically detectable length effect for the spinal cord has not been observed. The effects of chemotherapy and altered fractionation are also discussed. Brain necrosis in adults is rarely noted below 60 Gy in conventional fractionation, with imaging and clinical changes being observed generally only above 50 Gy. However, neurocognitive effects are observed at lower doses, especially in children. A more pronounced volume effect is believed to exist in the brain than in the spinal cord. Tumor progression may be hard to distinguish from radiation and chemotherapy effects. Diffuse white matter injury can be attributed to radiation and associated with neurological deficits, but leukoencephalopathy is rarely observed in the absence of chemotherapy. Subjective, objective, management, and analytic (SOMA) parameters related to radiation spinal cord and brain injury have been developed and presented on ordinal scales. 140 refs., 3 figs., 6 tabs

  1. Modelling and simulation of Holocene marine terrace development in Boso Peninsula, central Japan

    Science.gov (United States)

    Noda, Akemi; Miyauchi, Takahiro; Sato, Toshinori; Matsu'ura, Mitsuhiro

    2018-04-01

    In the southern part of Boso Peninsula, central Japan, we can observe a series of well-developed Holocene marine terraces. We modeled the development of these marine terraces by considering sea-level fluctuation and steady land uplift. The evolution of coastal landform is generally described as follows: altitude change = - erosion + deposition - sea-level rise + land uplift. In this study, the erosion rate is supposed to be proportional to the dissipation rate of wave energy, and the deposition rate of eroded materials to decay exponentially as they are transported seaward. The rate of sea-level rise is given by the time derivative of a sea-level curve obtained from the sediment core records of oxygen isotope ratios. Steady plate subduction generally brings about steady crustal uplift/subsidence independently of earthquake occurrence, and so the land-uplift rate is regarded as time independent on a long-term average. Our simulation results show that a pair of sea cliff and abrasion platform is efficiently formed about a stationary point of the sea-level curve. The Holocene sea-level curve has four peaks and three troughs, and so basically seven terraces are formed one by one during the past 10,000 yr. However, when the land-uplift rate is low, most of the terraces formed at older times sink in the sea. When the land-uplift rate is high, the overlap and/or reverse of older and younger terraces occur frequently, and so the correspondence between the age and present altitude of terraces is not necessarily one-to-one. Taking the land-uplift rate to be 3-4 mm/yr, we can reproduce a series of well-developed Holocene marine terraces in Boso Peninsula independently of coseismic uplifts. From these simulation results, we may conclude that the Holocene marine terraces in Boso Peninsula were developed as a result of the composite process of sea-level fluctuation and steady coastal uplift.

  2. Reliability of oscillometric central hemodynamic responses to an orthostatic challenge

    OpenAIRE

    Stoner, Lee; Bonner, Chantel; Credeur, Daniel; Lambrick, Danielle; Faulkner, James; Wadsworth, Daniel; Williams, Michelle A.

    2015-01-01

    BackgroundMonitoring central hemodynamic responses to an orthostatic challenge may provide important insight into autonomic nervous system function. Oscillometric pulse wave analysis devices have recently emerged, presenting clinically viable options for investigating central hemodynamic properties. The purpose of the current study was to determine whether oscillometric pulse wave analysis can be used to reliably (between-day) assess central blood pressure and central pressure augmentation (a...

  3. Hypersensitivity Responses in the Central Nervous System

    DEFF Research Database (Denmark)

    Khorooshi, Reza; Asgari, Nasrin; Mørch, Marlene Thorsen

    2015-01-01

    of pathology in neuromyelitis optica (NMO), a central nervous system (CNS) demyelinating disease where activated neutrophils infiltrate, unlike in MS. The most widely used model for MS, experimental autoimmune encephalomyelitis, is an autoantigen-immunized disease that can be transferred to naive animals...

  4. Seasonal and long-term change in lead deposition in central Japan: evidence for atmospheric transport from continental Asia

    International Nuclear Information System (INIS)

    Bellis, David J.; Satake, Kenichi; Inagaki, Michiko; Zeng, Jiye; Oizumi, Tsuyoshi

    2005-01-01

    Long-range transport of air pollution from continental Asia is currently an important issue concerning the Japanese environment, especially in regions susceptible to acidification due to low buffering capacity, such as Murakami, Niigata prefecture, located on the west coast of central Japan. Evidence for long-range transport was obtained through lead and lead isotopic analysis of 84 archived precipitation filters, showing seasonal changes in lead deposition from May 1999 to May 2002. Lead deposition was highest in winter and spring (November through May) each year and lowest in summer. Computed 72-h back trajectories showed that in winter air masses were predominantly transported from the northwest, passing over northern China and eastern Russia, whilst in summer air masses predominantly originated from the southeast passing over Japan. Lead isotopic analysis showed higher 208 Pb/ 206 Pb during winter, indicating that lead originated from a different source. A plot of 207 Pb/ 206 Pb vs. 208 Pb/ 206 Pb identified a thorogenic component, which is excess 208 Pb compared to a standard lead growth curve, indicative of certain lead ores and coals in continental Asia. The data provided evidence of long-range transport of lead from continental Asia to Japan. Bark pockets included within the trunks of two Japanese cedar trees harvested near Murakami, dating between 1972 and 1982, exhibited lead isotope ratios indicative of Japanese-sourced lead. In contrast, current (2003) bark showed thorogenic ratios, consistent with a relative decline in Japanese-sourced and increase in continental-sourced lead

  5. Overland flow connectivity in a forest plantation before and after tree thinning (Tochigi Prefecture, central Japan)

    Science.gov (United States)

    López-Vicente, Manuel; Onda, Yuichi; Sun, Xinchao; Kato, Hiroaki; Gomi, Takashi; Hiraoka, Marino

    2016-04-01

    Overland flow connectivity is a key factor to understand the redistribution dynamics of sediments, nutrients, radiotracers, etc., in the different compartments at channel, hillslope and catchment scales. Human organization of landscape elements has a significant control on runoff and soil redistribution processes. Construction of trails, forest roads and firewalls influence runoff connectivity (RC) in forested catchments. In this study we simulated RC in two forested catchments, called K2 (19.3 ha) and K3 (13.6 ha), located on the Mount Karasawa, in the Tochigi Prefecture in central Japan. Forest plantation includes Japanese cypress and cedar and covers 59% of the total area. Native broad-leaved trees (28%) and mixed forest occupy the rest of the study area. We selected the Index of runoff and sediment Connectivity (IC) of Borselli et al. (2008) to simulate three temporal scenarios: i) Sc-2011, before tree thinning (TT); ii) Sc-2012 after TT in most part of the forest plantation in K2 (32% of the total area); and iii) Sc-2013 after TT in some areas of the K3 catchment, affecting 38% of the total area. The study areas were defined from the coalescence point (139⁰ 36' 04" E, 36⁰ 22' 03" N) of both catchments upslope. Elevation ranges from 75 to 287 m a.s.l. and the mean slope steepness is of 67 and 65% in K2 and K3. Three different high resolution DEM-LiDAR maps at 0.5 x 0.5 m of cell size were used to run the IC model in each scenario. The permanent streams in the study area have a total length of 2123 m. The mean C-RUSLE factor was of 0.0225 in Sc-2011 and 21% and 25% higher in Sc-2012 and Sc-2013. The total length of the landscape linear elements incremented from 2482 m in Sc-2011 to 3151 m in Sc-2012 and Sc-2013 due to the construction of new skid trails in K2. The mean RC in the study area was of -4.536 in Sc-2011 and increased 7.4% and 8.9% in the Sc-2012 and Sc-2013, respectively, due to the tree thinning operations and the construction of new skid trails

  6. Parallel 3D Simulation of Seismic Wave Propagation in the Structure of Nobi Plain, Central Japan

    Science.gov (United States)

    Kotani, A.; Furumura, T.; Hirahara, K.

    2003-12-01

    We performed large-scale parallel simulations of the seismic wave propagation to understand the complex wave behavior in the 3D basin structure of the Nobi Plain, which is one of the high population cities in central Japan. In this area, many large earthquakes occurred in the past, such as the 1891 Nobi earthquake (M8.0), the 1944 Tonankai earthquake (M7.9) and the 1945 Mikawa earthquake (M6.8). In order to mitigate the potential disasters for future earthquakes, 3D subsurface structure of Nobi Plain has recently been investigated by local governments. We referred to this model together with bouguer anomaly data to construct a detail 3D basin structure model for Nobi plain, and conducted computer simulations of ground motions. We first evaluated the ground motions for two small earthquakes (M4~5); one occurred just beneath the basin edge at west, and the other occurred at south. The ground motions from these earthquakes were well recorded by the strong motion networks; K-net, Kik-net, and seismic intensity instruments operated by local governments. We compare the observed seismograms with simulations to validate the 3D model. For the 3D simulation we sliced the 3D model into a number of layers to assign to many processors for concurrent computing. The equation of motions are solved using a high order (32nd) staggered-grid FDM in horizontal directions, and a conventional (4th-order) FDM in vertical direction with the MPI inter-processor communications between neighbor region. The simulation model is 128km by 128km by 43km, which is discritized at variable grid size of 62.5-125m in horizontal directions and of 31.25-62.5m in vertical direction. We assigned a minimum shear wave velocity is Vs=0.4km/s, at the top of the sedimentary basin. The seismic sources for the small events are approximated by double-couple point source and we simulate the seismic wave propagation at maximum frequency of 2Hz. We used the Earth Simulator (JAMSTEC, Yokohama Inst) to conduct such

  7. Conflicting views on elder care responsibility in Japan.

    Science.gov (United States)

    Lee, Kristen Schultz

    2016-05-01

    I examine the attitudinal ambivalence created by conflicting social expectations regarding parent-child devotion, filial obligation and family membership, and gender norms in a national population of Japanese adults. I ask: in a context of rapidly changing family and elder care norms, how do different beliefs and attitudes overlap and conflict and how are they related to elder care preferences? I analyze data from the 2006 Japanese General Social Survey and use Latent Class Analysis to identify latent groups in the population defined by their beliefs and examine the relationship between class membership and elder care preferences. I found variation in the population with respect to the measured beliefs as well as a relationship between patterns of beliefs and choice of elder caregiver. I found conflicting expectations regarding elder care responsibility in one latent class and this class also expressed elder care preferences that conflict with at least some of their strongly held beliefs. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. Nuclear power plants making a comeback in Japan; El retorno de la centrales nucleares en Japon

    Energy Technology Data Exchange (ETDEWEB)

    Torralbo, J. R.

    2016-08-01

    We reproduce in this magazine the interesting article published by the president of the SNE in issue 46 of Cuadernos de Energia in October 2015, which describes the events that have taken place since the March 11, 2011 earthquake in Japan, the largest in its history, and the subsequent tsunami, which affected the Fukushima power plant, as well as the measures implemented since then and how some of this country nuclear power plants are being started up again. (Author)

  9. On the Effects of Central Japan Expressway's Commuter Toll Discount Policy in Nagoya Area

    Institute of Scientific and Technical Information of China (English)

    YING Jiangqian; Ryosuke Ando

    2007-01-01

    Road pricing policies have two equally important objectives that have to be considered: the optimal use of the road network and the fiscal sustainability for the management of the network. The aim of this work is to examine the effects on these two objectives of a recent pricing policy implemented in Japan's expressway networks. Recently the Nippon (Japan) Expressway Companies (NEXCO, operators of Japan's nation wide expressway network) have implemented several toll discount policies for users equipped with electronic toll collectors (ETCs). One of the policies is the commuter discount policy that discounts 50% for a journey on the NEXCO expressway no longer than 100 km during the commuting peak hours. This paper examines its effect on congestion reduction in the road network of Nagoya area and its influence on the use of expressways operated by another major local public expressway company in Nagoya. The congestion easing effect of this policy is compared with a potential marginal cost pricing scheme. These observations suggest that policy coordination regarding toll levels is needed for expressway corporations and transportation authorities for improving transportation efficiency of utilization of the whole network.

  10. Severe hypertriglyceridemia in Japan: Differences in causes and therapeutic responses.

    Science.gov (United States)

    Murase, Toshio; Okubo, Minoru; Ebara, Tetsu; Mori, Yasumichi

    Severe hypertriglyceridemia (>1000 mg/dL) has a variety of causes and frequently leads to life-threating acute pancreatitis. However, the origins of this disorder are unclear for many patients. We aimed to characterize the causes of and responses to therapy in rare cases of severe hypertriglyceridemia in a group of Japanese patients. We enrolled 121 patients from a series of case studies that spanned 30 years. Subjects were divided into 3 groups: (1) primary (genetic causes); (2) secondary (acquired); and (3) disorders of uncertain causes. In the last group, we focused on 3 possible risks factors for hypertriglyceridemia: obesity, diabetes mellitus, and heavy alcohol intake. Group A (n = 20) included 13 patients with familial lipoprotein lipase deficiency, 3 patients with apolipoprotein CII deficiency, and other genetic disorders in the rest of the group. Group B patients (n = 15) had various metabolic and endocrine diseases. In Group C (uncertain causes; n = 86), there was conspicuous gender imbalance (79 males, 3 females) and most male subjects were heavy alcohol drinkers. In addition, 18 of 105 adult patients (17%) had histories of acute pancreatitis. The cause of severe hypertriglyceridemia is uncertain in many patients. In primary genetic forms of severe hypertriglyceridemia, genetic diversity between populations is unknown. In the acquired forms, we found fewer cases of estrogen-induced hypertriglyceridemia than in Western countries. In our clinical experience, the cause of most hypertriglyceridemia is uncertain. Our work suggests that genetic factors for plasma triglyceride sensitivity to alcohol should be explored. Copyright © 2017 National Lipid Association. Published by Elsevier Inc. All rights reserved.

  11. Summary of Great East Japan Earthquake response at Onagawa Nuclear Power Station and further safety improvement measures

    International Nuclear Information System (INIS)

    Sato, Toru

    2013-01-01

    A large earthquake occurred on March 11, 2011 and tsunami was generated following it. The East Japan suffered serious damage by the earthquake and tsunami. This is called the Great East Japan Earthquake. Onagawa Nuclear Power Station (NPS) is located closest to the epicenter of Great East Japan Earthquake. We experienced intense shake by the earthquake and some flooding from the tsunami, however, we have succeeded safely cold shutdown of the reactors. In this paper, we introduce summary of Great East Japan Earthquake response a Onagawa NPS and safety improvement measures which are based on both experience of Onagawa NPS and lesson from Fukushima Daiichi NPS accident. (author)

  12. Reliability of oscillometric central hemodynamic responses to an orthostatic challenge.

    Science.gov (United States)

    Stoner, Lee; Bonner, Chantel; Credeur, Daniel; Lambrick, Danielle; Faulkner, James; Wadsworth, Daniel; Williams, Michelle A

    2015-08-01

    Monitoring central hemodynamic responses to an orthostatic challenge may provide important insight into autonomic nervous system function. Oscillometric pulse wave analysis devices have recently emerged, presenting clinically viable options for investigating central hemodynamic properties. The purpose of the current study was to determine whether oscillometric pulse wave analysis can be used to reliably (between-day) assess central blood pressure and central pressure augmentation (augmentation index) responses to a 5 min orthostatic challenge (modified tilt-table). Twenty healthy adults (26.4 y (SD 5.2), 55% F, 24.7 kg/m(2) (SD 3.8)) were tested on 3 different mornings in the fasted state, separated by a maximum of 7 days. Central hemodynamic variables were assessed on the left arm using an oscillometric device. Repeated measures analysis of variance indicated a significant main effect of the modified tilt-table for all central hemodynamic variables (P response to the tilt, central diastolic pressure increased by 4.5 mmHg (CI: 2.6, 6.4), central systolic blood pressure increased by 2.3 (CI: 4.4, 0.16) mmHg, and augmentation index decreased by an absolute - 5.3%, (CI: -2.7, -7.9%). The intra-class correlation coefficient values for central diastolic pressure (0.83-0.86), central systolic blood pressure (0.80-0.87) and AIx (0.79-0.82) were above the 0.75 criterion in both the supine and tilted positions, indicating excellent between-day reliability. Central hemodynamic responses to an orthostatic challenge can be assessed with acceptable between-day reliability using oscillometric pulse wave analysis. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  13. [A new stream of the next disaster response with a variety of hospital ship in Japan].

    Science.gov (United States)

    Kato, Soichiro; Yamaguchi, Yoshihiro

    2016-02-01

    In Japan, experience from an earthquake has always provided an opportunity to reconsider measures of disaster preparedness. To facilitate decision-making and its enforcement in a large-scale disaster response, a cross-agency organization and tough infrastructure are required as a foundation of crisis management. In the Fukushima nuclear power plant accident, the Fukushima Nuclear Disaster Management Center could not perform their mission due to the collapse of various infrastructure caused by the earthquake. The archipelago structure of Japan is easy terrain that provides approach from the shore to any place in the country; this makes it possible to plan effective relief operations. Therefore, in preparing for the next large-scale disaster, the use of a hospital ship has been discussed as one of the strong bases to combat collapse of infrastructure. For effective utilization of the ship, we will discuss the main points collated from experience of past disaster responses and training.

  14. Proposal of new framework in nuclear emergency response based on problem in East Japan Great Earthquake

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-08-15

    In the nuclear emergency response activity in a East Japan great earthquake, the weakness the frame and the activity procedure (scheme) of the emergency response activity of our country that had been constructed after the accident of JCO became clear. Especially, it is necessary to recognize the importance of the enhancement of a prior plan after not only provision to response but also the damage to the environment occurs in the emergency for measures for restoration. Moreover, it is necessary to examine a concrete strategy about the management system strengthening of the radiation exposure at the accident. In this study, the experience and the finding in a East Japan great earthquake are arranged. The accident scenario that should be targeted is rearranged, and it proposes a new frame in the nuclear emergency response field through the requirement examinations such as the points of procedure, equipment, and the capital machine parts that lie a regulations frame of the nuclear emergency response, the activity frame of the nuclear emergency response, and materialized of the nuclear emergency response activity. (author)

  15. Proposal of new framework in nuclear emergency response based on problem in East Japan Great Earthquake

    International Nuclear Information System (INIS)

    2013-01-01

    In the nuclear emergency response activity in a East Japan great earthquake, the weakness the frame and the activity procedure (scheme) of the emergency response activity of our country that had been constructed after the accident of JCO became clear. Especially, it is necessary to recognize the importance of the enhancement of a prior plan after not only provision to response but also the damage to the environment occurs in the emergency for measures for restoration. Moreover, it is necessary to examine a concrete strategy about the management system strengthening of the radiation exposure at the accident. In this study, the experience and the finding in a East Japan great earthquake are arranged. The accident scenario that should be targeted is rearranged, and it proposes a new frame in the nuclear emergency response field through the requirement examinations such as the points of procedure, equipment, and the capital machine parts that lie a regulations frame of the nuclear emergency response, the activity frame of the nuclear emergency response, and materialized of the nuclear emergency response activity. (author)

  16. Proposal of new framework in nuclear emergency response based on problem in East Japan Great Earthquake

    International Nuclear Information System (INIS)

    2012-01-01

    In the nuclear emergency response activity in a East Japan great earthquake, the weakness the frame and the activity procedure (scheme) of the emergency response activity of our country that had been constructed after the accident of JCO became clear. Especially, it is necessary to recognize the importance of the enhancement of a prior plan after not only provision to response but also the damage to the environment occurs in the emergency for measures for restoration. Moreover, it is necessary to examine a concrete strategy about the management system strengthening of the radiation exposure at the accident. In this study, the experience and the finding in a East Japan great earthquake are arranged. The accident scenario that should be targeted is rearranged, and it proposes a new frame in the nuclear emergency response field through the requirement examinations such as the points of procedure, equipment, and the capital machine parts that lie a regulations frame of the nuclear emergency response, the activity frame of the nuclear emergency response, and materialized of the nuclear emergency response activity. (author)

  17. State of research and perspective on adaptive response to low doses of ionizing radiation in Japan

    International Nuclear Information System (INIS)

    Sadao Hattori

    1997-01-01

    In a review article entitled ''Physical Benefits from Low Levels of Ionizing Radiation,'' published in Health Physics in December of 1982, Professor T.D. Luckey of the University of Missouri, asserted the ''radiation hormesis'' with 200 references. This resulted in the first International Symposium on Radiation Hormesis in Oakland, California (August 1985). CRIEPI consulted many specialists about Luckey's paper and studied many other papers such as Lorenz, 1954; Luckey, 1980, Liu et al., 1985. Radiation hormesis research in Japan has been based on the rationale that if Luckey's claim were to be true, radiation management in Japan has been extremely erroneous. CRIEPI organized a Hormesis Research Steering Committee composed of leading specialists in the field concerned, and began research in cooperation with a number of universities, as well as the National Cancer Research Institute, and the National Institute of Radiological Sciences. After obtaining interesting results in various experiments on the health effects of exposure to low doses of radiation, we have proceeded on an expanded program, which involves fourteen universities and two research institutes throughout Japan. The interesting results we obtained can be categorized in five groups. 1. Enhancement of immune systems such as lymphocytes and suppression of cancer, 2. Radio-adaptive response relating to the activation of DNA repair and adoptosis, 3. Rejuvenation of cells such as increase of SOD and cell membrane permeability, 4. Radiation effect on neuro-transmitting system through increase of key enzymes, 5. Others, including the therapy of adult-disease such as diabetes and hypertension. We are now carrying out experimental activities on the effects of low-dose radiation on mammals. After several years of research activities, we are recognizing Luckey's claim. Some basic surveys including Hiroshima Nagasaki and animal experiments in Japan have brought us valuable informations on the health effects of low

  18. Nuclear emergency preparedness and response in Japan. Risk management and communication regarding nuclear events

    International Nuclear Information System (INIS)

    Sato, Hajime

    2011-01-01

    Severe accidents at nuclear plants can result in long-standing and large-scale disasters encompassing wide areas. The public may have special concerns regarding these plants and radiation-related health risks. It has therefore been argued that risk communications efforts, along with rigid safety management of nuclear plants, are imperative to prevent such accidents, mitigate their impacts, and alleviate public concerns. This article introduces a set of laws, acts, codes, and guidelines concerning nuclear safety in Japan. In addition, the preparedness and mitigation plans and programs for dealing with nuclear accidents and possible disasters are also discussed. Furthermore, the ongoing accidents at the Fukushima nuclear power plants following the Great East Japan Earthquake in 2011, and the government response to them are presented. A set of points regarding the management and communications of power plant accidents are discussed. (author)

  19. Growth and reproduction of the sea snake, Emydocephalus ijimae, in the central Ryukyus, Japan: a mark and recapture study.

    Science.gov (United States)

    Masunaga, Gen; Ota, Hidetoshi

    2003-04-01

    A mark and recapture study was carried out for three years on a population of the Ijima's sea snake, Emydocephalus ijimae, in the coastal shallow water of Zamamijima Island, central Ryukyus, Japan. The relatively high recapture (47% of 167 marked snakes) suggests that E. ijimae is a particularly philopatric, sedentary species among the sea snakes. The sex ratio (male: female), approximately 1.6:1, significantly skewed from 1:1. The growth rate in SVL declined with growth, with females thoroughly growing better than males. Males and females were estimated to begin reproductive activity in the second or third summer and the third spring after birth, respectively. Frequency of female reproduction is guessed to vary from annual to biennial, or even less frequent.

  20. Hypercoagulability in response to elevated body temperature and central hypovolemia

    DEFF Research Database (Denmark)

    Meyer, Martin; Ostrowski, Sisse R; Overgaard, Flemming Anders

    2013-01-01

    Coagulation abnormalities contribute to poor outcomes in critically ill patients. In trauma patients exposed to a hot environment, a systemic inflammatory response syndrome, elevated body temperature, and reduced central blood volume occur in parallel with changes in hemostasis and endothelial...... damage. The objective of this study was to evaluate whether experimentally elevated body temperature and reduced central blood volume (CBV) per se affects hemostasis and endothelial activation....

  1. Emergency response arrangements for the transport of irradiated nuclear fuel from Japan to Europe in Japanese territorial waters

    International Nuclear Information System (INIS)

    Ikeda, T.; Inada, T.; Narahara, S.; Cheshire, R.D.; Lee, G.

    1993-01-01

    About 90 % of nuclear fuel irradiated in Japanese nuclear power stations is transported to UK and France for reprocessing. Pacific Nuclear Transport Ltd (PNTL), a subsidiary of British Nuclear Fuels plc (BNFL), owns and operates its own fleet of 5 purpose built ships specially designed for the transport of flasks containing irradiated fuel from Japan to Europe. These vessels sail to Japan on 8 to 10 voyages per year from the BNFL's Marine Terminal at Barrow in UK via Cherbourg Port in France. On arrival in Japan empty flasks are delivered to Japanese nuclear power stations, and full flasks are collected for the return journey to Europe. Whilst the probability of a serious flask incident involving the release of radioactivity is very small, it is nevertheless important to plan for such an emergency. In the case of an incident BNFL will provide an emergency response. If an incident occurs in Japanese territorial waters, the initial response will be provided by Nuclear Services Company (NSC), who are based in Japan (the head office in Tokyo, Tokai Office in Ibaraki Prefecture and Tsuruga Office in Fukui Prefecture) and contracted to BNFL to provide a similar response to that available from UK. This paper describes the communication links which have been established between UK and Japan and the internal communication within Japan. It also describes the emergency equipent held in Japan, the training of teams and the results of exercises jointly carried out with BNFL. (J.P.N.)

  2. Transition of radiation protection standards in ICRP recommendations and Japan's response

    International Nuclear Information System (INIS)

    Shirabe, Masashi

    2016-01-01

    Radiation protection standards are the standards set for the purpose of preventing radiation hazard and other damage. This paper confirm what the International Commission on Radiological Protection (ICRP) recommended against the standard value on public exposure in Japan's laws and regulations, and how the Japanese government responded in introducing it into Japan's laws and regulations. There were delays of 6 to 12 years for the introduction of ICRP recommendations into the laws and regulations. Compared with response to the copyright treaty, which was extremely quick with the delays of only 1 to 2 years, these delays were very large. In Japan's laws and regulations, there are no regulations on the standard value for public exposure, and introduction of the recommended standard value of 1 mSv/year from ICRP has been avoided by the government. It is supposed that the reason for not introducing radiation dose limit and dose constraint value of public exposure was due to the lobbying of electric companies. After the Fukushima Daiichi nuclear accident, the former Nuclear Safety Commission set the reference level for emergency exposure situation at 20 mSv/year. Although there is the long-term target of 1 mSv/year for existing exposure, no reference level has been set yet. Due to these delays or avoidances, the rights of people suffering from radiation exposure are restricted, while perhaps the benefits of electric companies are being protected. (A.O.)

  3. Fukushima after the Great East Japan Earthquake: lessons for developing responsive and resilient health systems

    Science.gov (United States)

    Fukuma, Shingo; Ahmed, Shahira; Goto, Rei; Inui, Thomas S; Atun, Rifat; Fukuhara, Shunichi

    2017-01-01

    Background On 11 March 2011, the Great East Japan Earthquake, followed by a tsunami and nuclear–reactor meltdowns, produced one of the most severe disasters in the history of Japan. The adverse impact of this ‘triple disaster’ on the health of local populations and the health system was substantial. In this study we examine population–level health indicator changes that accompanied the disaster, and discuss options for re–designing Fukushima’s health system, and by extension that of Japan, to enhance its responsiveness and resilience to current and future shocks. Methods We used country–level (Japan–average) or prefecture–level data (2005–2014) available from the portal site of Official Statistics of Japan for Fukushima, Miyagi, and Iwate, the prefectures that were most affected by the disaster, to compare trends before (2005–2010) and after (2011–2014) the ‘disaster’. We made time–trend line plots to describe changes over time in age–adjusted cause–specific mortality rates in each prefecture. Findings All three prefectures, and in particular Fukushima, had lower socio–economic indicators, an older population, lower productivity and gross domestic product per capita, and less higher–level industry than the Japan average. All three prefectures were ‘medically underserved’, with fewer physicians, nurses, ambulance calls and clinics per 100 000 residents than the Japan average. Even before the disaster, age–adjusted all–cause mortality in Fukushima was in general higher than the national rates. After the triple disaster we found that the mortality rate due to myocardial infarction increased substantially in Fukushima while it decreased nationwide. Compared to Japan average, spikes in mortality due to lung disease (all three prefectures), stroke (Iwate and Miyagi), and all–cause mortality (Miyagi and Fukushima) were also observed post–disaster. The cause–specific mortality rate from cancer followed similar trends in

  4. Crustal characteristic variation in the central Yamato Basin, Japan Sea back-arc basin, deduced from seismic survey results

    Science.gov (United States)

    Sato, Takeshi; No, Tetsuo; Miura, Seiichi; Kodaira, Shuichi

    2018-02-01

    The crustal structure of the Yamato Bank, the central Yamato Basin, and the continental shelf in the southern Japan Sea back-arc basin is obtained based on a seismic survey using ocean bottom seismographs and seismic shot to elucidate the back-arc basin formation processes. The central Yamato Basin can be divided into three domains based on the crustal structure: the deep basin, the seamount, and the transition domains. In the deep basin domain, the crust without the sedimentary layer is about 12-13 km thick. Very few units have P-wave velocity of 5.4-6.0 km/s, which corresponds to the continental upper crust. In the seamount and transition domains, the crust without the sedimentary layer is about 12-16 km thick. The P-wave velocities of the upper and lower crusts differs among the deep basin, the seamount, and the transition domains. These results indicate that the central Yamato Basin displays crustal variability in different domains. The crust of the deep basin domain is oceanic in nature and suggests advanced back-arc basin development. The seamount domain might have been affected by volcanic activity after basin opening. In the transition domain, the crust comprises mixed characters of continental and oceanic crust. This crustal variation might represent the influence of different processes in the central Yamato Basin, suggesting that crustal development was influenced not only by back-arc opening processes but also by later volcanic activity. In the Yamato Bank and continental shelf, the upper crust has thickness of about 17-18 km and P-wave velocities of 3.3-4.1 to 6.6 km/s. The Yamato Bank and the continental shelf suggest a continental crustal character.

  5. Surface rupturing earthquakes repeated in the 300 years along the ISTL active fault system, central Japan

    Science.gov (United States)

    Katsube, Aya; Kondo, Hisao; Kurosawa, Hideki

    2017-06-01

    Surface rupturing earthquakes produced by intraplate active faults generally have long recurrence intervals of a few thousands to tens of thousands of years. We here report the first evidence for an extremely short recurrence interval of 300 years for surface rupturing earthquakes on an intraplate system in Japan. The Kamishiro fault of the Itoigawa-Shizuoka Tectonic Line (ISTL) active fault system generated a Mw 6.2 earthquake in 2014. A paleoseismic trench excavation across the 2014 surface rupture showed the evidence for the 2014 event and two prior paleoearthquakes. The slip of the penultimate earthquake was similar to that of 2014 earthquake, and its timing was constrained to be after A.D. 1645. Judging from the timing, the damaged area, and the amount of slip, the penultimate earthquake most probably corresponds to a historical earthquake in A.D. 1714. The recurrence interval of the two most recent earthquakes is thus extremely short compared with intervals on other active faults known globally. Furthermore, the slip repetition during the last three earthquakes is in accordance with the time-predictable recurrence model rather than the characteristic earthquake model. In addition, the spatial extent of the 2014 surface rupture accords with the distribution of a serpentinite block, suggesting that the relatively low coefficient of friction may account for the unusually frequent earthquakes. These findings would affect long-term forecast of earthquake probability and seismic hazard assessment on active faults.

  6. Smectite-zeolite envelope surrounding the Tsukiyoshi uranium deposit, central Japan. A natural analogue study

    International Nuclear Information System (INIS)

    Utada, Minoru

    2003-01-01

    The Tsukiyoshi uranium deposit in Gifu Prefecture is the largest one in Japan. It is embedded in lower part of the Mizunami Group of Miocene age. Relating to the existence of this uranium deposit, the constituent minerals in sediments were studied by XRD and SEM, using many drilling cores. The most abundant authigenic mineral is smectite. The amount of smectite increases generally from upper to lower horizons, and a highly smectitized zone is situated around the uranium deposit. Smectitization predominated in mafic glassy grains of sediments, which was probably formed in early burial diagenesis. Zeolites including clinoptilolite-heulandite, mordenite, analcime, chabazite and philipsite are secondly abundant authigenic minerals. They seem to have been formed at early to late diagenetic stages. Opaline silica is rather rare. Carbonate minerals, including calcite, dolomite, siderite and rhodocrosite are common. They may be formed by diagenesis as well. Gypsum and pyrite occur in upper horizons and lower horizons, respectively. In particular, a highly smectitized zone including pyrite probably played an important role for retarding the migration of uranium and as a result keeping the uranium deposit for past one million years. This smectite-zeolite envelope surrounding the Tsukiyoshi uranium deposit is regarded as a natural analogue of the buffer materials surrounding the high-level radioactive waste repository. (author)

  7. The Centralization and Decentralization of Telemedicine Networks in Korea and Japan

    Directory of Open Access Journals (Sweden)

    Soo-kyung Park

    2013-06-01

    Full Text Available This study scrutinizes telemedicine networks with regard to regionalization and the propensities and determinants of core telemedicine users (doctors and patients by employing two case areas, Choongbook in Korea and Kagawa in Japan. According to the results, telemedicine networks in Choongbook are dominated by an inter-regional level (in particular, a national level, and most of the telemedicine networks are observed between clinical sites in Choongbook and tertiary care centers in Kyunggi. In contrast, telemedicine networks in Kagawa are dispersed within the diagnostic boundary of Kagawa at a regional level. Interviews with crucial decision-makers revealed the reasons why many patients enjoy health care via telemedicine at an inter-regional level, which include psychological considerations regarding quality and level of health care services, personal stakes in telemedicine service sites, acceptability and credibility of good tertiary care centers, and easy access to and use of medical institutions. In Kagawa, both the existing health care system and the telemedicine system support the maintenance of stable regional health care within Kagawa. Importantly, human relationships based on the regional health care system contribute to creating telemedicine networks within the original purpose of the telemedicine system regarding regionalization. Also, telemedicine’s technological value, convenience, and utility are associated with the regionalization of telemedicine networks within one diagnostic area.

  8. Radionuclides deposition and fine sediment transport in a forested watershed, central Japan

    Science.gov (United States)

    Nam, S.; Gomi, T.; Kato, H.; Tesfaye, T.; Onda, Y.

    2011-12-01

    We investigated radionuclides deposition and fine sediment transport in a 13 ha headwater watershed, Tochigi prefecture, located in 98.94 km north of Tokyo. The study site was within Karasawa experimental forest, Tokyo University of Agriculture and Technology. We conducted fingerprinting approach, based on the activities of fallout radionuclides, including caesium-134 (Cs-134) caesium-137 (Cs-137) and excess lead-210 (Pb-210ex). For indentifying specific sources of fine sediment, we sampled tree, soil on forested floor, soil on logging road surface, stream bed and stream banks. We investigated the radionuclides (i.e., as Cs-134, Cs-137 and Pb-210ex) deposition on tree after accident of nuclear power plants on March 11, 2011. We sampled fruits, leaves, branches, stems, barks on Japanese cedar (Sugi) and Japanese cypress (Hinoki). To analyze the samples, gammaray spectrometry was performed at a laboratory at the University of Tsukuba (Tsukuba City, Japan) using n-type coaxial low-energy HPGe gamma detectors (EGC-200-R and EGC25-195-R of EURYSIS Co., Lingolsheim, France) coupled with a multichannel analyzer. We also collected soil samples under the forest canopy in various soil depths from 2, 5, 10, 20, 30 cm along transect of hillslopes. Samples at forest road were collected road segments crossing on the middle section of monitoring watersheds. Fine sediment transport in the streams were collected at the outlet of 13 ha watersheds using integrated suspended sediment samplers. This study indicates the some portion of radio nuclide potentially remained on the tree surface. Part of the deposited radionuclides attached to soil particles and transported to the streams. Most of the fine sediment can be transported on road surface and/or near stream side (riparian zones).

  9. CENTRAL AMYGDALOID INVOLVEMENT IN NEUROENDOCRINE CORRELATES OF CONDITIONED STRESS RESPONSES

    NARCIS (Netherlands)

    ROOZENDAAL, B; KOOLHAAS, JM; BOHUS, B

    The purpose of this study was to examine the effects of bilateral electrolytic lesions of the central nucleus of the amygdala (CEA) in comparison with sham lesions on neuroendocrine responses during conditioned emotional stress in male Wistar rats. Lesions in the CEA, made either before or after the

  10. Innate immune responses in central nervous system inflammation

    DEFF Research Database (Denmark)

    Finsen, Bente; Owens, Trevor

    2011-01-01

    In autoimmune diseases of the central nervous system (CNS), innate glial cell responses play a key role in determining the outcome of leukocyte infiltration. Access of leukocytes is controlled via complex interactions with glial components of the blood-brain barrier that include angiotensin II...

  11. Immediate behavioural responses to earthquakes in Christchurch, New Zealand, and Hitachi, Japan.

    Science.gov (United States)

    Lindell, Michael K; Prater, Carla S; Wu, Hao Che; Huang, Shih-Kai; Johnston, David M; Becker, Julia S; Shiroshita, Hideyuki

    2016-01-01

    This study examines people's immediate responses to earthquakes in Christchurch, New Zealand, and Hitachi, Japan. Data collected from 257 respondents in Christchurch and 332 respondents in Hitachi revealed notable similarities between the two cities in people's emotional reactions, risk perceptions, and immediate protective actions during the events. Respondents' physical, household, and social contexts were quite similar, but Hitachi residents reported somewhat higher levels of emotional reaction and risk perception than did Christchurch residents. Contrary to the recommendations of emergency officials, the most frequent response of residents in both cities was to freeze. Christchurch residents were more likely than Hitachi residents to drop to the ground and take cover, whereas Hitachi residents were more likely than Christchurch residents to evacuate immediately the building in which they were situated. There were relatively small correlations between immediate behavioural responses and demographic characteristics, earthquake experience, and physical, social, or household context. © 2016 The Author(s). Disasters © Overseas Development Institute, 2016.

  12. Stand Dynamics and Biomass Increment in a Lucidophyllous Forest over a 28-Year Period in Central Japan

    Directory of Open Access Journals (Sweden)

    Siyu Chen

    2017-10-01

    Full Text Available Secondary lucidophyllous forest is one of the dominant forests in human-dominated subtropical/warm-temperate regions in East Asia. There were few direct monitoring techniques to elucidate the following hypotheses: (a self-thinning may govern the stand development process and (b wood production decline can be observed during secondary succession in a lucidophyllous forest. We conducted a long-term study at a permanent plot in central Japan, since 1989. The forest consists mainly of Castanopsis cuspidata in a canopy layer, Cleyera japonica, and Eurya japonica in a subtree layer. During the 28-year period, the basal area of the stand significantly increased due to the growth of C. cuspidata, from 29.18 ± 1.84 (87.8% of total to 38.71 ± 2.22 m2 ha−1 (91.9%, while the stem density of C. cuspidata significantly decreased from 666 ± 13 to 404 ± 10 stems ha−1 in proportion to accumulating biomass (117.8 to 166.6 ton ha−1. The annual woody net primary production ranged from 2.40 ± 0.13 to 3.93 ± 0.33 ton ha−1 year−1 as a nearly 70-year-old forest. There was no age-related decline of woody net primary production (NPP was found during secondary succession, and the growth of individual tree still increased when the self-thinning process governed the stand.

  13. Exploring sub-daily to seasonal variations in methane exchange in a single-crop rice paddy in central Japan

    Science.gov (United States)

    Iwata, Hiroki; Mano, Masayoshi; Ono, Keisuke; Tokida, Takeshi; Kawazoe, Takahiro; Kosugi, Yoshiko; Sakabe, Ayaka; Takahashi, Kenshi; Miyata, Akira

    2018-04-01

    Season-long methane (CH4) exchange was observed in a rice paddy field in central Japan (Kanto Region) using the eddy covariance technique to clarify the variations in environmental controls on CH4 exchange in different stages of cultivation. Before heading of rice plant, the CH4 emission depended on wind speed and soil temperature. The soil temperature dependence can be due to an increase in CH4 production, higher molecular diffusion, and higher conductance within rice plant at higher soil temperature. An occurrence of ebullitive emission was also suggested from the wind speed dependence. After heading was completed, relative humidity and water temperature influenced CH4 emission. The amplitude of the diurnal variation in emission increased from 0.03 μmolm-2s-1 in the late pre-heading stage to 0.13 μmolm-2s-1 in the post-heading stage. Induced convective throughflow within the rice aerenchyma after the change in plant structure was attributable to this variation in environmental controls after the heading. After drainage, CH4 emission was confined to short periods after strong rain events. The water level controlled the timing of emission, most likely by influencing the diffusion efficiency from the anoxic soil to the atmosphere and CH4 oxidation in the surface oxic zone. The variation in the dominant transport pathway needs to be accounted for in terrestrial ecosystem models to accurately predict CH4 emission from rice paddies.

  14. Radiometric age determination on some granitic rocks in the Hida Range, central Japan. Remarkable age difference across a fault

    International Nuclear Information System (INIS)

    Ito, Hisatoshi; Tanaka, Kazuhiro

    1999-01-01

    K-Ar and zircon fission-track dating was carried out on some granitic rocks in the Hida Range, central Japan. The samples analyzed were collected on both sides of one of the major faults in the Hida Range: the Kurobe-Takase fracture zone. Ages obtained west of the fault are ∼60 Ma, while those obtained to the east of the fault are less than ∼5 Ma. These results indicate a remarkable age difference across the fault. The Okukurobe granite, located west of the fault, cooled rapidly from ∼600degC to ∼240degC between 60-55 Ma, and the Kanazawa granodiorite, located east of the fault, cooled rapidly from ∼600degC to ∼240degC between 5-1 Ma. The Okukurobe granite has remained cooler than ∼240degC since ∼55 Ma. Thus, it was found that the granitic rocks across the fault have experienced a remarkable different cooling history. (author)

  15. Input-Output Budget of Nitrogen and the Effect of Experimentally Changed Deposition in the Forest Ecosystems in Central Japan

    Directory of Open Access Journals (Sweden)

    Junko Shindo

    2001-01-01

    Full Text Available To evaluate the current nitrogen (N status in Japanese forests, field measurements of rainfall, throughfall, litter layer percolation, and soil solution percolation were conducted in a red pine stand (Kannondai and a deciduous stand (Yasato located in central Japan. N input via throughfall was 31 and 14 kg ha–1 year–1and output below rooting zone was 9.6 and 5.5 kg ha1 year–1 in Kannondai and in Yasato, respectively. Two thirds of input N were retained in plant-soil systems. Manipulation of N input was carried out. Ionic constituents were removed from throughfall with ion exchange resin at removal sites and ammonium nitrate containing twice the N of the throughfall was applied at N addition sites periodically. SO42– output below 20-cm soil layer changed depending on the input, while NO3– output was regulated mainly by the internal cycle and effect of manipulation was undetected. These Japanese stands were generally considered to have a larger capacity to assimilate N than NITREX sites in Europe. However, N output fluxes had large spatial variability and some sites in Kannondai showed high N leaching below rooting zone almost balanced with the input via throughfall.

  16. First fossil occurrence of a filefish (Tetraodontiformes; Monacanthidae) in Asia, from the Middle Miocene in Nagano Prefecture, central Japan.

    Science.gov (United States)

    Miyajima, Yusuke; Koike, Hakuichi; Matsuoka, Hiroshige

    2014-04-10

    A new fossil filefish, Aluterus shigensis sp. nov., with a close resemblance to the extant Aluterus scriptus (Osbeck), is described from the Middle Miocene Bessho Formation in Nagano Prefecture, central Japan. It is characterized by: 21 total vertebrae; very slender and long first dorsal spine with tiny anterior barbs; thin and lancet-shaped basal pterygiophore of the spiny dorsal fin, with its ventral margin separated from the skull; proximal tip of moderately slender first pterygiophore of the soft dorsal fin not reaching far ventrally; soft dorsal-fin base longer than anal-fin base; caudal peduncle having nearly equal depth and length; and tiny, fine scales with slender, straight spinules. The occurrence of this fossil filefish from the Bessho Formation is consistent with the influence of warm water currents suggested by other fossils, but it is inconsistent with the deep-water sedimentary environment of this Formation. This is the first fossil occurrence of a filefish in Asia; previously described fossil filefishes are known from the Pliocene and Pleistocene of Italy, the Pliocene of Greece, and the Miocene and Pliocene of North America. These fossil records suggest that the genus Aluterus had already been derived and was widely distributed during the Middle Miocene with taxa closely resembling Recent species.

  17. Geological and Hydrodynamical Examination of the Bathyal Tsunamigenic Origin of Miocene Conglomerates in Chita Peninsula, Central Japan

    Science.gov (United States)

    Tachibana, Toru; Tsuji, Yoshinobu

    2011-06-01

    A conglomerate appears on a rocky coast called "Tsubutega-ura Coast", located on the southwestern coast near the southern tip of the Chita Peninsula, Aichi Prefecture, central Japan. The conglomerate belongs to Miocene sedimentary rocks termed the Morozaki Group. The conglomerate includes meter-scale boulders, indicating that it was formed by an extraordinary event. In the geological investigation, we observed that the conglomerate shows alternate changes of paleocurrent directions between seaward and landward. This feature is supposed to be formed by tsunami currents. In the hydrodynamical investigation, we obtained following results: (1) the lowest limit of a current velocity to move a boulder of about 3 m in diameter would be about 2-3 m/s, (2) the speed of tsunami currents reproduced by tsunami simulation exceeds 3 m/s at 300 m in depth when the tsunami is generated by a gigantic earthquake with magnitude 9.0 or more, (3) the transport distance of the boulder would be several hundred meters to several kilometers by one tsunami event caused by a gigantic earthquake. We conclude that tsunamis best explain the formation of the conglomerate deposited in upper bathyal environments about 200-400 m depth, both from geological and hydrodynamical viewpoints.

  18. Georesistivity structure in the central part of North-Eastern Japan Arc; Tohoku chiho chubu chiiki no denki dendodo kozo

    Energy Technology Data Exchange (ETDEWEB)

    Fujinawa, Y. [National Research Institute for Disaster Prevention, Tsukuba (Japan); Kawakami, N. [GERD Geothermal Energy Research and Development Co. Ltd., Tokyo (Japan); Ueshima, M. [The University of Tokyo, Tokyo (Japan). Earthquake Research Institute; Honkura, Y. [Tokyo Institute of Technology, Tokyo (Japan)

    1998-03-13

    MT measurement of transects was made in the central part of North-Eastern Japan Arc to clarify tectonics of subduction zones. 1-D, 2-D and 3-D resistivity structures are observed in surface layers, and zones shallower and deeper than a Conrad surface, respectively. A main structure direction is S-N or NNE-SSW. Ishinomaki-Chokai tectonic line and low- resistivity zones due to Quaternary volcanos (Naruko, Onikobe) exist in a backbone range region. Resistivity is 100{Omega}{center_dot}m or less by Bostick Inversion except Mesozoic and Palaeozoic layers in the southern Kitakami mountainous region, resulting in a good agreement with previous results in a north transect. Resistivity is several {Omega}{center_dot}m and depth is several km around Shinjo basin and in surface layers of Kitakami River region. The backbone range region shows complex resistivity structures because of volcanic activity and wide-area hot water activity. High-resistivity layers correspond to stable Mesozoic and Palaeozoic land layers. Seismic velocity increases in the low-resistivity zone. Earthquake generally occurs at the boundary between resistivity structures. 68 refs., 9 figs., 2 tabs.

  19. Regulation of Neurotransmitter Responses in the Central Nervous System.

    Science.gov (United States)

    1987-05-01

    and identify by block number) FIELD GROUP SUB-GROUP J’-aminobutyric acid; yclic AM’P; neuromodulation ; brain 1ABTAT(Continue on reverse if necessary and...crucial enzyme for regulating neuromodulation in brain. Given the ultimate goal of developing novel pharmacological agents for N! manipulating...central nervous system function, the discovery of a biochemical response to a neuromodulator can be considered a major step in that direction. Thus, up to

  20. Immune response induction in the central nervous system

    DEFF Research Database (Denmark)

    Owens, Trevor; Babcock, Alicia

    2002-01-01

    The primary function of the immune response is protection of the host against infection with pathogens, including viruses. Since viruses can infect any tissue of the body, including the central nervous system (CNS), it is logical that cells of the immune system should equally have access to all...... tissues. Nevertheless, the brain and spinal cord are noted for their lack of immune presence. Relative to other organ systems, the CNS appears immunologically privileged. Furthermore, when immune responses do occur in the CNS, they are frequently associated with deleterious effects such as inflammatory...

  1. Current situation regarding central venous port implantation procedures and complications: a questionnaire-based survey of 11,693 implantations in Japan.

    Science.gov (United States)

    Shiono, Masatoshi; Takahashi, Shin; Takahashi, Masanobu; Yamaguchi, Takuhiro; Ishioka, Chikashi

    2016-12-01

    We conducted a nationwide questionnaire-based survey to understand the current situation regarding central venous port implantation in order to identify the ideal procedure. Questionnaire sheets concerning the number of implantation procedures and the incidence of complications for all procedures completed in 2012 were sent to 397 nationwide designated cancer care hospitals in Japan in June 2013. Venipuncture sites were categorized as chest, neck, upper arm, forearm, and others. Methods were categorized as landmark, cut-down, ultrasound-mark, real-time ultrasound guided, venography, and other groups. We received 374 responses (11,693 procedures) from 153 centers (38.5 %). The overall complication rates were 7.4 % for the chest (598/8,097 cases); 6.8 % for the neck (157/2325); 5.2 % for the upper arm (54/1,033); 7.3 % for the forearm (9/124); and 6.1 % for the other groups (7/114). Compared to the chest group, only the upper arm group showed a significantly lower incidence of complications (P = 0.010), and multivariate logistic regression (odds ratio 0.69; 95 % confidence interval 0.51-0.91; P = 0.008) also showed similar findings. Real-time ultrasound-guided puncture was most commonly used in the upper arm group (83.8 %), followed by the neck (69.8 %), forearm (53.2 %), chest (41.8 %), and other groups (34.2 %). Upper arm venipuncture with ultrasound guidance seems the most promising technique to prevent complications of central venous port implantation.

  2. Growth and Reproduction of the Sea Snake, Emydocephalus ijimae, in the Central Ryukyus, Japan : a Mark and Recapture Study(Ecology)

    OpenAIRE

    Gen, Masunaga; Hidetoshi, Ota; Graduate School of Science and Engeneering, University of the Ryukyus; Tropical Biosphere Research Center, University of the Ryukyus

    2003-01-01

    A mark and recapture study was carried out for three years on a population of the Ijima's sea snake, Emydocephalus ijimae, in the coastal shallow water of Zamamijima Island, central Ryukyus, Japan. The relatively high recapture (47% of 167 marked snakes) suggests that E. ijimae is a particularly philopatric, sedentary species among the sea snakes. The sex ratio (male: female), approximately 1.6:1, significantly skewed from 1:1. The growth rate in SVL declined with growth, with females thoroug...

  3. An Attempt at Captive Breeding of the Endangered Newt Echinotriton andersoni, from the Central Ryukyus in Japan

    Directory of Open Access Journals (Sweden)

    Masayuki Sumida

    2013-07-01

    Full Text Available Anderson’s crocodile newt (Echinotriton andersoni is distributed in the Central Ryukyu Islands of southern Japan, but environmental degradation and illegal collection over the last several decades have devastated the local populations. It has therefore been listed as a class B1 endangered species in the IUCN Red List, indicating that it is at high risk of extinction in the wild. The species is also protected by law in both Okinawa and Kagoshima prefectures. An artificial insemination technique using hormonal injections could not be applied to the breeding of this species in the laboratory. In this study we naturally bred the species, and tested a laboratory farming technique using several male and female E. andersoni pairs collected from Okinawa, Amami, and Tokunoshima Islands and subsequently maintained in near-biotopic breeding cages. Among 378 eggs derived from 17 females, 319 (84.4% became normal tailbud embryos, 274 (72.5% hatched normally, 213 (56.3% metamorphosed normally, and 141 (37.3% became normal two-month-old newts; in addition, 77 one- to three-year-old Tokunoshima newts and 32 Amami larvae are currently still growing normally. Over the last five breeding seasons, eggs were laid in-cage on slopes near the waterfront. Larvae were raised in nets maintained in a temperature-controlled water bath at 20 °C and fed live Tubifex. Metamorphosed newts were transferred to plastic containers containing wet sponges kept in a temperature-controlled incubator at 22.5 °C and fed a cricket diet to promote healthy growth. This is the first published report of successfully propagating an endangered species by using breeding cages in a laboratory setting for captive breeding. Our findings on the natural breeding and raising of larvae and adults are useful in breeding this endangered species and can be applied to the preservation of other similarly wild and endangered species such as E. chinhaiensis.

  4. TREE SPECIES CLASSIFICATION OF BROADLEAVED FORESTS IN NAGANO, CENTRAL JAPAN, USING AIRBORNE LASER DATA AND MULTISPECTRAL IMAGES

    Directory of Open Access Journals (Sweden)

    S. Deng

    2017-10-01

    Full Text Available This study attempted to classify three coniferous and ten broadleaved tree species by combining airborne laser scanning (ALS data and multispectral images. The study area, located in Nagano, central Japan, is within the broadleaved forests of the Afan Woodland area. A total of 235 trees were surveyed in 2016, and we recorded the species, DBH, and tree height. The geographical position of each tree was collected using a Global Navigation Satellite System (GNSS device. Tree crowns were manually detected using GNSS position data, field photographs, true-color orthoimages with three bands (red-green-blue, RGB, 3D point clouds, and a canopy height model derived from ALS data. Then a total of 69 features, including 27 image-based and 42 point-based features, were extracted from the RGB images and the ALS data to classify tree species. Finally, the detected tree crowns were classified into two classes for the first level (coniferous and broadleaved trees, four classes for the second level (Pinus densiflora, Larix kaempferi, Cryptomeria japonica, and broadleaved trees, and 13 classes for the third level (three coniferous and ten broadleaved species, using the 27 image-based features, 42 point-based features, all 69 features, and the best combination of features identified using a neighborhood component analysis algorithm, respectively. The overall classification accuracies reached 90 % at the first and second levels but less than 60 % at the third level. The classifications using the best combinations of features had higher accuracies than those using the image-based and point-based features and the combination of all of the 69 features.

  5. Community structures and activity of denitrifying microbes in a forested catchment in central Japan: survey using nitrite reductase genes

    Science.gov (United States)

    Ohte, N.; Aoki, M.; Katsuyama, C.; Suwa, Y.; Tange, T.

    2012-12-01

    To elucidate the mechanisms of denitrification processes in the forested catchment, microbial ecological approaches have been applied in an experimental watershed that has previously investigated its hydrological processes. The study catchment is located in the Chiba prefecture in central Japan under the temperate Asian monsoon climate. Potential activities of denitrification of soil samples were measured by incubation experiments under anoxic condition associated with Na15NO3 addition. Existence and variety of microbes having nitrite reductase genes were investigated by PCR amplification, cloning and sequencings of nirK and nirS fragments after DNA extraction. Contrary to our early expectation that the potential denitrification activity was higher at deeper soil horizon with consistent groundwater residence than that in the surface soil, denitrification potential was higher in shallower soil horizons than deeper soils. This suggested that the deficiency of NO3- as a respiratory substrate for denitrifier occurred in deeper soils especially in the summer. However, high denitrification activity and presence of microbes having nirK and nirS in surface soils usually under aerobic condition was explainable by the fact that the majority of denitrifying bacteria have been recognized as a facultative anaerobic bacterium. This also suggests the possibility of that denitrification occurs even in the surface soils if the wet condition is provided by rainwater during and after a storm event. Community structures of microbes having nirK were different between near surface and deeper soil horizons, and ones having nirS was different between saturated zone (under groundwater table) and unsaturated soil horizons. These imply that microbial communities with nisK are sensitive to the concentration of soil organic matters and ones with nirS is sensitive to soil moisture contents.

  6. The efficacy of support vector machines (SVM) in robust determination of earthquake early warning magnitudes in central Japan

    Science.gov (United States)

    Reddy, Ramakrushna; Nair, Rajesh R.

    2013-10-01

    This work deals with a methodology applied to seismic early warning systems which are designed to provide real-time estimation of the magnitude of an event. We will reappraise the work of Simons et al. (2006), who on the basis of wavelet approach predicted a magnitude error of ±1. We will verify and improve upon the methodology of Simons et al. (2006) by applying an SVM statistical learning machine on the time-scale wavelet decomposition methods. We used the data of 108 events in central Japan with magnitude ranging from 3 to 7.4 recorded at KiK-net network stations, for a source-receiver distance of up to 150 km during the period 1998-2011. We applied a wavelet transform on the seismogram data and calculating scale-dependent threshold wavelet coefficients. These coefficients were then classified into low magnitude and high magnitude events by constructing a maximum margin hyperplane between the two classes, which forms the essence of SVMs. Further, the classified events from both the classes were picked up and linear regressions were plotted to determine the relationship between wavelet coefficient magnitude and earthquake magnitude, which in turn helped us to estimate the earthquake magnitude of an event given its threshold wavelet coefficient. At wavelet scale number 7, we predicted the earthquake magnitude of an event within 2.7 seconds. This means that a magnitude determination is available within 2.7 s after the initial onset of the P-wave. These results shed light on the application of SVM as a way to choose the optimal regression function to estimate the magnitude from a few seconds of an incoming seismogram. This would improve the approaches from Simons et al. (2006) which use an average of the two regression functions to estimate the magnitude.

  7. Corporate social responsibility in Japan from the Edo period to the Fukushima nuclear accident

    International Nuclear Information System (INIS)

    Rolland-Piegue, E.

    2011-01-01

    Behind an apparently universal adherence to corporate social responsibility, differences in approaches are lurking with roots in distinct traditions of thought. Japanese business values date back to merchants during the Edo period and to the pioneers of Japanese capitalism during the Meiji period. They have always emphasized the diversity of all the parties - and not just shareholders - who contribute to a company's prosperity and should share in the benefits. Imported from Europe in 2003, corporate social responsibility was quickly institutionalized by Japanese firms that want to comply with international standards. This concept, Japanese-style, barely touches on social questions, which are referred to traditional values; but focuses instead on environmental issues and consumer protection. Non governmental organizations are not very active in Japan, and the state refuses to take a leading role even though its pro-business policy supports corporate social responsibility and should help, for example, diffuse the new standard, Iso-26000. Since March 2011, a new phase, laden with uncertainty, has started. The most devastating earthquake since World War II and the crisis at the Fukushima Daiichi nuclear power station should lead the Japanese to raise fundamental questions about what they expect from firms and public authorities. (author)

  8. A Paleozoic Japan-type subduction-accretion system in the Beishan orogenic collage, southern Central Asian Orogenic Belt

    Science.gov (United States)

    Song, Dongfang; Xiao, Wenjiao; Windley, Brian F.; Han, Chunming; Tian, Zhonghua

    2015-05-01

    Magmatic arcs ascribed to oceanic lithosphere subduction played a dominant role in the construction of the accretionary Central Asian Orogenic Belt (CAOB). The Beishan orogenic collage, situated between the Tianshan Orogen to the west and the Inner Mongolia Orogen to the east, is a key area to understanding the subduction and accretionary processes of the southern CAOB. However, the nature of magmatic arcs in the Beishan and the correlation among different tectonic units along the southern CAOB are highly ambiguous. In order to investigate the subduction-accretion history of the Beishan and put a better spatial and temporal relationship among the tectonic belts along the southern CAOB, we carried out detailed field-based structural geology and LA-ICP-MS zircon U-Pb geochronological as well as geochemical studies along four cross-sections across crucial litho-tectonic units in the central segment of the Beishan, mainly focusing on the metamorphic assemblages and associated plutons and volcanic rocks. The results show that both the plutonic and volcanic rocks have geochemical characteristics similar to those of subduction-related rocks, which favors a volcanic arc setting. Zircons from all the plutonic rocks yield Phanerozoic ages and the plutons have crystallization ages ranging from 464 ± 2 Ma to 398 ± 3 Ma. Two volcanic-sedimentary rocks yield zircons with a wide age range from Phanerozoic to Precambrian with the youngest age peaks at 441 Ma and 446 Ma, estimated to be the time of formation of the volcanic rocks. These new results, combined with published data on ophiolitic mélanges from the central segment of the Beishan, favor a Japan-type subduction-accretion system in the Cambrian to Carboniferous in this part of the Paleo-Asian Ocean. The Xichangjing-Niujuanzi ophiolite probably represents a major suture zone separating different tectonic units across the Beishan orogenic collage, while the Xiaohuangshan-Jijitaizi ophiolitic mélange may represent a

  9. Visit of Mr. Susumu Yoda, Japanese Atomic Energy Commission, Mr. Nobuo Natsume, Vice-President, Central Research Institute of Electric Power Industry, Japan (CRIEPI), Mr. Nobuya Yoshiki, CRIEPI, Mrs. Seiko Ichikawa, Interpreter, with Mr. Taylor of CERN, visiting SM18

    CERN Multimedia

    Laurent Guiraud

    2000-01-01

    Visit of Mr. Susumu Yoda, Japanese Atomic Energy Commission, Mr. Nobuo Natsume, Vice-President, Central Research Institute of Electric Power Industry, Japan (CRIEPI), Mr. Nobuya Yoshiki, CRIEPI, Mrs. Seiko Ichikawa, Interpreter, with Mr. Taylor of CERN, visiting SM18

  10. Investigation of local-dimensional galvanic distortion on MT data in the central part of Northeastern Japan; Tohoku chiho no MT data ni mirareru kyokushoteki sanjigensei no eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Kawakami, N; Takasugi, S [GERD Geothermal Energy Research and Development Co. Ltd., Tokyo (Japan); Fujinawa, Y [National Research Institute for Disaster Prevention, Tsukuba (Japan)

    1996-10-01

    Groom-Bailey decomposition analysis was carried out to investigate regional 3-D galvanic distortion on MT data in the central part of Northeastern Japan. Measuring sites were located nearly along the east-west line crossing Northeastern Japan. Three measuring lines (A, B, C) from the north to the south were prepared, and only data on the C line were analyzed in this paper. As a result, twist and shear were estimated to be not zero depending on local distortion in most of the sites. It was thus clarified that this method is not always perfect. This method was effective for regional 2-D structures, however, its application was doubtful to complicated 3-D underground structures in Japan. In order to obtain more accurate results, 2-D analysis using the impedance including no local distortion effect was necessary after the preliminary Groom-Bailey decomposition analysis. The direction of the wide area geological structure of Northeastern Japan was estimated to be N-S direction near NNW-SSE one. 6 refs., 12 figs., 1 tab.

  11. IRBA SERIES : Accounting In Japan

    OpenAIRE

    Arai, Kiyomitsu

    1994-01-01

    Preface / Legal and Conceptual Framework of Accounting in Japan / Setting Accounting Standards in Japan - The American Influence and The Present Status / Accounting Education and Profession in Japan / The International Harmonization of Accounting Standards / The Accounting Standard Setting in Japan and Its Responses to International Accounting Standards / Selected Bibliography for Accounting in Japan

  12. Central Japan's Atera Active Fault's Wide-Fractured Zone: An Examination of the Structure and In-situ Crustal Stress

    Science.gov (United States)

    Ikeda, R.; Omura, K.; Matsuda, T.; Mizuochi, Y.; Uehara, D.; Chiba, A.; Kikuchi, A.; Yamamoto, T.

    2001-12-01

    In-situ downhole measurements and coring within and around an active fault zone are needed to better understand the structure and material properties of fault rocks as well as the physical state of active faults and intra-plate crust. Particularly, the relationship between the stress concentration state and the heterogeneous strength of an earthquake fault zone is important to estimate earthquake occurrence mechanisms which correspond to the prediction of an earthquake. It is necessary to compare some active faults in different conditions of the chrysalis stage and their relation to subsequent earthquake occurrence. To better understand such conditions, "Active Fault Zone Drilling Project" has been conducted in the central part of Japan by the National Research Institute for Earth Science and Disaster Prevention. The Nojima fault which appeared on the surface by the 1995 Great Kobe earthquake (M=7.2) and the Neodani fault created by the 1981 Nobi earthquake, the greatest inland earthquake M=8.0 in Japan, have been drilled through the fault fracture zones. During these past four years, a similar experiment and research at the Atera fault, of which some parts seem to have been dislocated by the 1586 Tensyo earthquake, has been undertaken. The features of the Atera fault are as follows: (1) total length is about 70 km, (2) general trend is NW45_Kwith a left-lateral strike slip, (3) slip rate is estimated as 3-5 m/1000 yrs. and the average recurrence time as 1700 yrs., (4) seismicity is very low at present, and (5) lithologies around the fault are basically granitic rocks and rhyolite. We have conducted integrated investigations by surface geophysical survey and drilling around the Atera fault. Six boreholes have been drilled from the depth of 400 m to 630 m. Four of these boreholes are located on a line crossing the fracture zone of the Atera fault. Resistivity and gravity structures inferred from surface geophysical surveys were compared with the physical properties

  13. Long-range atmospheric transport of volatile monocarboxylic acids with Asian dust over a high mountain snow site, central Japan

    Directory of Open Access Journals (Sweden)

    T. Mochizuki

    2016-11-01

    Full Text Available To understand the long-range transport of monocarboxylic acids from the Asian continent to the Japanese islands, we collected snowpack samples from a pit sequence (depth ca. 6 m at the Murodo-Daira snowfield near the summit of Mt. Tateyama, central Japan, in 2009 and 2011. Snow samples (n = 16 were analyzed for normal (C1–C10, branched chain (iC4–iC6, aromatic (benzoic and toluic acid isomers, and hydroxyl (glycolic and lactic monocarboxylic acids, together with inorganic ions and dissolved organic carbon (DOC. Acetic acid (C2 was found to be a dominant species (average 125 ng g−1, followed by formic acid (C1 (85.7 ng g−1 and isopentanoic acid (iC5 (20.0 ng g−1. We found a strong correlation (r =  0.88 between formic plus acetic acids and non-sea-salt Ca2+ that is a proxy of Asian dust. Contributions of total monocarboxylic acids to DOC in 2009 (21.2 ± 11.6 % were higher than that in 2011 (3.75 ± 2.62 %, being consistent with higher intensity of Asian dust in 2009 than in 2011. Formic plus acetic acids also showed a positive correlation (r =  0.90 with benzoic acid that is a tracer of automobile exhaust, indicating that monocarboxylic acids and their precursors are largely emitted from anthropogenic sources in China and/or secondarily produced in the atmosphere by photochemical processing. In addition, the ratio of formic plus acetic acids to nss–Ca2+ (0.27 was significantly higher than those (0.00036–0.0018 obtained for reference dust materials of Chinese loess deposits from the Tengger and Gobi deserts. This result suggests that volatile and semi-volatile organic acids are adsorbed on the alkaline dust particles during long-range atmospheric transport. Entrainment of organic acids by dusts is supported by a good correlation (r = 0.87 between formic plus acetic acids and pH of melt snow samples. Our study suggests that Asian alkaline dusts may be a carrier of volatile monocarboxylic

  14. Stability of radioactive minerals in an oxidizing hydrogeological environment: new results from an alluvial placer deposit, Naegi district, central Japan

    International Nuclear Information System (INIS)

    Sasao, Eiji; Komuro, Kosei; Nakata, Masataka

    2009-01-01

    Study of the stability of radioactive minerals in a placer deposit in the Naegi District, southeastern Gifu Prefecture, Central Japan contributes to understanding the modes of nuclide migration under various hydrogeological environments in the tectonically active Japanese Island Arc system. The placer deposit is embedded in basal conglomerates of the lower-most alluvial sequences, exposed to a near-surface, oxidizing hydrogeological environment. The mineral samples, ranging in mesh size from 120 to 250, were identified after sieving and magnetic separation to be mainly cassiterite, thorite, monazite, and topaz, with subordinate amounts of zircon, fergusonite-(Y), xenotime and wolframite. Observations using optical and scanning microscopy indicated that many grains of zircon have well-preserved crystal faces. Most monazite and fergusonite-(Y) grains are partly abraded and corroded whereas thorite grains are highly abraded and corroded. This indicates that under an oxidizing hydrogeological environment, the mechanical durability and geological stability decrease from zircon to monazite/fergusonite-(Y) to thorite, which correlates well with the Mohs's hardness scale. Cut and polished thorite grains display a high degree of alteration. The altered portions have higher Th, Fe and Y contents, and lower U and Si contents in comparison with the unaltered portions, indicating leaching of U and Si. In the fergusonite-(Y) grains, the altered portions have higher Th, Nb and Ta contents, and lower U and Y contents in comparison with the unaltered portions, indicate leaching of U and Y. Thus it is determined that uranium is strongly leached in an oxidizing hydrogeological environment. The leaching behaviour is dependent on mineralogy and is consistent with thermodynamic estimates. The alteration rate of fergusonite-(Y) was calculated to range from 0.05 to 0.000025 μm/year based on the thickness of the external alteration film and the duration of exposure to the oxidizing

  15. The effect of demand response on purchase intention of distributed generation: Evidence from Japan

    International Nuclear Information System (INIS)

    Nakada, Tatsuhiro; Shin, Kongjoo; Managi, Shunsuke

    2016-01-01

    Participation in demand response (DR) may affect a consumer's electric consumption pattern through consumption load curtailment, a shift in the consumption timing or increasing the utilization of distributed generation (DG). This paper attempts to provide empirical evidence of DR's effect on DG adoption by household consumers. By using the original Internet survey data of 5442 household respondents in Japan conducted in January 2015, we focus on the effect of the time-of-use (TOU) tariff on the purchasing intention of photovoltaic systems (PV). The empirical results show the following: 1) current TOU plan users have stronger PV purchase intentions than the other plan users, 2) respondents who are familiar with the DR program have relatively higher purchase intentions compared with their counterparts, and 3) when the respondents are requested to assume participation in the virtual TOU plan designed for the survey, which resembles plans currently available through major companies, 1.2% of the households have decided to purchase PV. In addition, we provide calculations of TOU's impacts on the official PV adoption and emissions reduction targets, and discuss policy recommendations to increase recognitions and participations in TOU programs. - Highlights: •Studies the effect of demand response on purchase intention of PV. •Uses originally collected Internet Japanese household survey data in 2015. •Finds that time-of-use (TOU) plan has positive effect on PV purchase intentions. •Calculates latent TOU impacts on PV installations and emissions reduction targets. •Discusses policy recommendations to increase participations in TOU programs.

  16. Discordant K-Ar ages between hornblende and biotite from the Tanzawa tonalitic pluton in the southern Fossa Magna, central Japan

    International Nuclear Information System (INIS)

    Sato, Kohei; Shibata, Ken; Uchiumi, Shigeru

    1986-01-01

    K-Ar ages were determined for hornblende and biotite in three tonalites from the Tanzawa pluton in the southern Fossa Magna, central Japan. The two minerals show discordant ages of 10.1 and 10.7 Ma for hornblende and 4.6 - 5.1 Ma for biotite. The age data and field evidence indicate that the pluton was emplaced in the Tanzawa Group in Middle Miocene time and its slow cooling (ca. 50 deg C/Ma in average) resulted in younger ages of boitites than hornblendes due to lower closure temperature for biotite. (author)

  17. Processing insect abundance: trading and fishing of zazamushi in Central Japan (Nagano Prefecture, Honshū Island).

    Science.gov (United States)

    Césard, Nicolas; Komatsu, Seiji; Iwata, Akihisa

    2015-11-11

    This article presents the links between technique, commerce and consumption in fishing for zazamushi, a mixture of aquatic insect larvae sold as food souvenirs in Japan. Since zazamushi are mainly collected for economic reasons, we suggest that demand for them has incited technical development among collectors in order to fish more insects. Several fishermen and traders were interviewed in semi-directed interviews about their practices and knowledge. To understand the passage from a faunal composition to a commercial composition, our research follows a fishing session closely, as well as the selection of insects that follows it. The insects collected were separated from inanimate matter, then identified, counted and weighed at each stage of the process. Our results suggest that the current technique corresponds to an evolution in subsistence and recreational collecting towards a more systematic fishing of the insects, the aim of which is commercial. In their response to trade issues, the collectors have moved away from the banks to fish the insects in the river current, thus increasing the amount of one species captured compared to another. Although the technique is efficient (and similar to other harvesting techniques), it requires the thorough sorting of organic debris and insects (in our example, the catch contains approximately 78 % of inanimate matter and 22 % of insects, of which 3.29 % are retained for consumption, i.e., less than 2 out of 100 insects). The selection of insects to be consumed takes place mainly during cleaning. This stage depends on traders and reflects the different compositions sold as souvenirs. Our research shows that the consumption of insects is not explained just by ecological factors that are favourable or unfavourable, but also by technological and economic factors related to their commerce. It suggests that the traders have gradually established the insects that are currently sold as zazamushi and that this commercial development

  18. Undergraduate nursing students' perceptions about disaster preparedness and response in Istanbul, Turkey, and Miyazaki, Japan: a cross-sectional study.

    Science.gov (United States)

    Öztekin, Seher Deniz; Larson, Eric Edwin; Yüksel, Serpil; Altun Uğraş, Gülay

    2015-04-01

    Although the awareness of disasters has increased among nurses, the concept of disaster preparedness and response has not been sufficiently explored with undergraduate nursing students. The aim of this study was to assess and compare the perceptions of students regarding disaster preparedness and response that live in different earthquake-prone cities; Istanbul, Turkey and Miyazaki, Japan. A cross-sectional study employing seven questions was conducted in a final group of 1053 nursing students from Istanbul, Turkey, and Miyazaki, Japan. Most study respondents were female, aged 18-22 years, with a high proportion of second year students in both cities. Istanbul's students had more knowledge about disaster preparedness and response in relation to age and year of university, showing statistically significant differences. Istanbul's highest rated responses to disaster characteristics were on structural elements and injuries/deaths, while Miyazaki's was "unpredictable/sudden/disorganized". Respondents in Istanbul identified earthquakes as the disaster most likely to occur, while respondents in Miyazaki identified typhoon/hurricane. Study participants responded that they could provide caregiver roles during a disaster event rather than triage or managerial roles as disaster responders. Disaster characteristics were not described by one third of the students. Of the two-thirds that were described, most were of events that were highly predictable because of their frequencies in the given areas. Universities need to target and then focus on high-risk factors in their areas and have disaster plans for students who can provide triage and managerial nursing roles as disaster responders. © 2014 The Authors. Japan Journal of Nursing Science © 2014 Japan Academy of Nursing Science.

  19. Occupational safety and health aspects of corporate social responsibility reporting in Japan from 2004 to 2012.

    Science.gov (United States)

    Nagata, Tomohisa; Nakata, Akinori; Mori, Koji; Maruyama, Takashi; Kawashita, Futoshi; Nagata, Masako

    2017-05-02

    A number of companies publish corporate social responsibility (CSR) reporting in booklets and other publicly available formats. The purpose of this paper is to clarify the nine-year (2004-2012) trend of occupational safety and health (OSH) activities as described in CSR reporting (by industry sector and company size). We investigated CSR reporting on the website in all Japanese companies listed on the first section of the Tokyo Stock Exchange. The data were extracted from CSR reporting of each company every year from 2004 to 2012. We counted the pages dedicated to information on OSH activities by industry sector and company size and calculated the rate of OSH divided by total CSR-related activities. The number of companies publishing CSR reports increased in all industry sectors, although the rate of inclusion of OSH activity within CSR reports increased only among sectors such as construction, manufacturing, transportation, and commerce. Among all company size, CSR reporting increased constantly throughout all observed years. The proportion of companies that had described OSH in CSR reporting increased from 2004 to 2012, and 76.5% companies had described OSH activities in 2012. The average number of pages of CSR-related report was 34.2 in 2004, increasing to 43.1 in 2012. The proportion of described pages of OSH activities in total CSR reporting increased gradually, and 2.7% in 2012. The focus of CSR reporting gradually shifted from 'environment' to 'social activity including OSH'. Majority of companies are putting more emphasis on OSH in CSR reporting in Japan.

  20. Occupational safety and health aspects of corporate social responsibility reporting in Japan from 2004 to 2012

    Directory of Open Access Journals (Sweden)

    Tomohisa Nagata

    2017-05-01

    Full Text Available Abstract Background A number of companies publish corporate social responsibility (CSR reporting in booklets and other publicly available formats. The purpose of this paper is to clarify the nine-year (2004–2012 trend of occupational safety and health (OSH activities as described in CSR reporting (by industry sector and company size. Methods We investigated CSR reporting on the website in all Japanese companies listed on the first section of the Tokyo Stock Exchange. The data were extracted from CSR reporting of each company every year from 2004 to 2012. We counted the pages dedicated to information on OSH activities by industry sector and company size and calculated the rate of OSH divided by total CSR-related activities. Results The number of companies publishing CSR reports increased in all industry sectors, although the rate of inclusion of OSH activity within CSR reports increased only among sectors such as construction, manufacturing, transportation, and commerce. Among all company size, CSR reporting increased constantly throughout all observed years. The proportion of companies that had described OSH in CSR reporting increased from 2004 to 2012, and 76.5% companies had described OSH activities in 2012. The average number of pages of CSR-related report was 34.2 in 2004, increasing to 43.1 in 2012. The proportion of described pages of OSH activities in total CSR reporting increased gradually, and 2.7% in 2012. The focus of CSR reporting gradually shifted from ‘environment’ to ‘social activity including OSH’. Conclusions Majority of companies are putting more emphasis on OSH in CSR reporting in Japan.

  1. Decentralization and centralization of healthcare resources: investigating the associations of hospital competition and number of cardiologists per hospital with mortality and resource utilization in Japan.

    Science.gov (United States)

    Park, Sungchul; Lee, Jason; Ikai, Hiroshi; Otsubo, Tetsuya; Imanaka, Yuichi

    2013-11-01

    To investigate the associations of hospital competition and number of cardiologists per hospital (indicating the decentralization and centralization of healthcare resources, respectively) with 30-day in-hospital mortality, healthcare spending, and length of stay (LOS) among patients with acute myocardial infarction (AMI) in Japan. We collected data from 23,197 AMI patients admitted to 172 hospitals between 2008 and 2011. Hospital competition and number of cardiologists per hospital were analyzed as exposure variables in multilevel regression models for in-hospital mortality, healthcare spending, and LOS. Other covariates included patient, hospital, and regional variables; as well as the use of percutaneous coronary intervention (PCI). Hospitals in competitive regions and hospitals with a higher number of cardiologists were both associated lower in-hospital mortality. Additionally, hospitals in competition regions were also associated with longer LOS durations, whereas hospitals with more cardiologists had higher spending. The use of PCI was also associated with reduced mortality, increased spending and increased LOS. Centralization of cardiologists at the hospital level and decentralization of acute hospitals at the regional level may be contributing factors for improving the quality of care in Japan. Policymakers need to strike a balance between these two approaches to improve healthcare provision and quality. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  2. A report from the second US/Japan workshop on global change research: Environmental response technologies (mitigation and adaptation). United States-Japan Science and Technology Agreement

    Energy Technology Data Exchange (ETDEWEB)

    Edgerton, S. [comp.] [National Science Foundation, Washington, DC (United States). Committee on Earth and Environmental Sciences; Mizuno, Tateki [comp.] [National Inst. for Resources and Environment, MITI (Japan)

    1993-12-31

    The Second US - Japan Workshop on Global Change: Environmental Response Technologies for Global Change was hosted by the Program on Resources at the East-West Center, in Honolulu, Hawaii on February 1--3, 1993, on behalf of the United States Committee on Earth and Environmental Sciences (CEES) of the Federal Coordinating Council for Science, Engineering, and Technology (FCCSET). This workshop brought together over fifty leading scientists from the two countries to review existing technologies and to identify needed research on the development of new technologies for mitigation and adaptation of global change. The Workshop was organized around three areas of research: (1) capture, fixation/utilization, and disposal of CO{sub 2} (e.g. CO{sub 2}, separation and capture technologies, ocean and land disposal of CO{sub 2}; (2) energy production and conservation technologies to reduce greenhouse gas emissions (e.g. combustion efficiency, non-carbon based energy technologies, energy conservation technologies); and (3) adaptation technologies and practices related to global climate change (e.g., adaptation responses of crops to climate change, adapting urban infrastructure for climate change). Priorities for joint research in each of these areas were discussed. Selected papers have been processed separately for inclusion in the Energy Science and Technology Database.

  3. Comparison between the European Central Bank as a New Monetary Experiment and other Major - Central Banks - US Federal Reserve and Bank of Japan

    Directory of Open Access Journals (Sweden)

    Tache I.

    2014-12-01

    Full Text Available Our goal is to make a survey of three major central banks practices and to emphasize both the different national characteristics and the similarities derived from the global changes of financial environment. Using a descriptive methodology, the comparison will concern the central banks’ goals, the institutional and organizational structures, strategies and tools of monetary policy

  4. Housing system transformations in Japan and South Korea: divergent responses to neo-liberal forces

    NARCIS (Netherlands)

    Ronald, R.; Kyung, S.

    2013-01-01

    Despite different pathways and approaches to housing and public provision, considerations of East Asian developmental regimes have tended to categorise Japan and South Korea as different versions of a similar type of welfare regime. This paper addresses the roles housing systems and policies have

  5. Central adaptation of pain perception in response to rehabilitation of musculoskeletal pain

    DEFF Research Database (Denmark)

    Andersen, Lars L; Andersen, Christoffer H; Sundstrup, Emil

    2012-01-01

    Understanding the mechanisms of long-standing musculoskeletal pain and adaptations in response to physical rehabilitation is important for developing optimal treatment strategies. The influence of central adaptations of pain perception in response to rehabilitation of musculoskeletal pain remains...

  6. Spatial variation in low-level 134Cs in the coastal sediments off central Honshu in the Sea of Japan. Implications for delivery, migration, and redistribution patterns

    International Nuclear Information System (INIS)

    Inoue, Mutsuo; Uemura, H.; Kofuji, H.; Shirotani, Y.; Nagao, S.; Fujimoto, K.; Takata, H.; Kudo, N.

    2017-01-01

    In 2014 and 2015, we examined the spatial distribution of cesium-134 (half-life: 2.06 years) from the Fukushima Dai-ichi Nuclear Power Plant (FDNPP) in marine sediments within coastal-basin areas (water depths of 40-520 m) off central Honshu Island (the main island of Japan) in the Sea of Japan. The 134 Cs concentrations in both the surface sediment (0-1 cm depth) and whole-core inventory exhibited wide variations, and were highest at the site closest to the Agano River Estuary area (6.7 Bq/kg-dry and 886 Bq/m 2 , respectively). This indicates that 134 Cs in coastal areas was delivered by riverine suspended solids (SS). Given the spatial variation in 134 Cs concentrations, we believe that 134 Cs partially migrated northeastward within ∼50 km along Honshu Island (at water depths shallower than ∼140 m), and southwestward, including the Sado Basin area. This is predominantly attributable to the transport of SS by bottom currents and unsteady downward delivery onto the steep slopes of the basin. The total amount of 134 Cs in the study area in 2014 was estimated at approximately 0.6 TBq (decay-corrected to March 11, 2011, date of FDNPP accident). (author)

  7. Frost damage of bricks composing a railway tunnel monument in Central Japan: field monitoring and laboratory simulation

    Science.gov (United States)

    Thomachot, C.; Matsuoka, N.; Kuchitsu, N.; Morii, M.

    2005-07-01

    Bricks of tunnels and bridges of Usui Pass railway (Japan) exposed to north are subject to frost damage. Average depth of erosion due to detachment of angular blocks is around 1-1.5 cm. In order to assess this weathering and to understand its mechanism, an experimental study was carried out in the field and laboratory. Field monitoring showed the combination of seasonal and diurnal freezing with a maximum of heave when the freezing front reached 5 cm depth. Bricks taken from the site were submitted to unidirectional freezing at capillary and vacuum saturation in the laboratory. Results showed that frost damage of bricks was favoured by high saturation level and repetition of freeze-thaw cycles.

  8. Frost damage of bricks composing a railway tunnel monument in Central Japan: field monitoring and laboratory simulation

    Directory of Open Access Journals (Sweden)

    C. Thomachot

    2005-01-01

    Full Text Available Bricks of tunnels and bridges of Usui Pass railway (Japan exposed to north are subject to frost damage. Average depth of erosion due to detachment of angular blocks is around 1-1.5 cm. In order to assess this weathering and to understand its mechanism, an experimental study was carried out in the field and laboratory. Field monitoring showed the combination of seasonal and diurnal freezing with a maximum of heave when the freezing front reached 5 cm depth. Bricks taken from the site were submitted to unidirectional freezing at capillary and vacuum saturation in the laboratory. Results showed that frost damage of bricks was favoured by high saturation level and repetition of freeze-thaw cycles.

  9. [Expression of negative emotional responses to the 2011 Great East Japan Earthquake: Analysis of big data from social media].

    Science.gov (United States)

    Miura, Asako; Komori, Masashi; Matsumura, Naohiro; Maeda, Kazutoshi

    2015-06-01

    In this article, we investigated the expression of emotional responses to the 2011 Great East Japan Earthquake by analyzing the frequency of negative emotional terms in tweets posted on Twitter, one of the most popular social media platforms. We focused on differences in time-series variations and diurnal changes between two kinds of disasters: natural disasters (earthquakes and tsunamis) and nuclear accidents. The number of tweets containing negative emotional responses increased sharply shortly after the first huge earthquake and decreased over time, whereas tweets about nuclear accidents showed no correlation with elapsed time. Expressions of anxiety about natural disasters had a circadian rhythm, with a peak at midnight, whereas expressions of anger about the nuclear accident were highly sensitive to critical events related to the accident. These findings were discussed in terms of similarities and differences compared to earlier studies on emotional responses in social media.

  10. Seismic velocity structure and spatial distribution of reflection intensity off the Boso Peninsula, Central Japan, revealed by an ocean bottom seismographic experiment

    Science.gov (United States)

    Kono, Akihiro; Sato, Toshinori; Shinohara, Masanao; Mochizuki, Kimihiro; Yamada, Tomoaki; Uehira, Kenji; Shinbo, Takashi; Machida, Yuuya; Hino, Ryota; Azuma, Ryosuke

    2016-04-01

    Off the Boso Peninsula, central Japan, where the Sagami Trough is in the south and the Japan Trench is in the east, there is a triple junction where the Pacific plate (PAC), the Philippine Sea plate (PHS) and the Honshu island arc (HIA) meet each other. In this region, the PAC subducts beneath the PHS and the HIA, and the PHS subducts beneath the HIA. Due to the subduction of 2 oceanic plates, numerous seismic events took place in the past. In order to understand these events, it is important to image structure of these plates. Hence, many researchers attempted to reveal the substructure from natural earthquakes and seismic experiments. Because most of the seismometers are placed inland area and the regular seismicity off Boso is inactive, it is difficult to reveal the precise substructure off Boso area using only natural earthquakes. Although several marine seismic experiments using active sources were conducted, vast area remains unclear off Boso Peninsula. In order to improve the situation, a marine seismic experiment, using airgun as an active source, was conducted from 30th July to 4th of August, 2009. The survey line has 216 km length and 20 Ocean Bottom Seismometers (OBSs) were placed on it. We estimated 2-D P-wave velocity structure from the airgun data using the PMDM (Progressive Model Development Method; Sato and Kenett, 2000) and the FAST (First Arrival Seismic Tomography ; Zelt and Barton, 1998). Furthermore, we identified the probable reflection phases from the data and estimated the location of reflectors using Travel time mapping method (Fujie et al. 2006). We found some reflection phases from the data, and the reflectors are located near the region where P-wave velocity is 5.0 km/s. We interpret that the reflectors indicate the plate boundary between the PHS and the HIA. The variation of the intensity of reflection along the upper surface of PHS seems to be consistent with the result from previous reflection seismic experiment conducted by Kimura et

  11. Seed bank response to prescribed fire in the central Appalachians.

    Science.gov (United States)

    Thomas M. Schuler; Melissa Thomas Van-Gundy; Mary B. Adams; W. Mark. Ford

    2010-01-01

    Pre- and post-treatment seed-bank characteristics of woody species were compared after two prescribed fires in a mesic mixed-oak forest in the central Appalachians. Nineteen woody species were identified from soil samples. Mean species richness declined but evenness did not after prescribed burning. The...

  12. Exclusion, violence, and community responses in Central American ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Its field presence throughout Central America, understanding of the context, will also help ensure that research is conducted in a secure and ethical fashion. Institutional coordinates: Lead Institution Facultad Latinoamericana de las Ciencias Sociales (FLACSO), Sede Costa Rica 200 metros sur, 25 este de Plaza del Sol

  13. Acoustic and gravity features of mud volcanoes along the seaward part of the Kumano forearc basin, Nankai region, central Japan

    Science.gov (United States)

    Asada, M.

    2017-12-01

    Mud volcanoes (MV) are geological features that are observed all over the world, especially along plate convergent margins. MVs bring fluid and sediment to the surface from depth. MVs around Japan are expected to transport of information from the shallow portions of the seismogenic zone. The Kumano forearc basin (FAB) in the Nankai region is the most studied area in Japan. It is bounded by a shelf on the north, and the Kumano Basin edge fault zone (KBEFZ) on the south. The Kumano FAB has 1-2 km of sediment and overlies the accretionary prism. There are at least 14 MVs in the Kumano Basin. Most of them are found over the northern basin floor, and at least one MV is at the KBEFZ. The MV at the KBEFZ is imaged on a 3D seismic data set as a small topographic feature on seafloor with a disrupted BSR below it. On high-resolution acoustic imagery, it is an 80 100m-high hill with a crater-like depression. It is characterized by a negative ph anomaly detected just above it. High-backscatter seafloor recognized around the MV suggests that harder seafloor exists in that area. To determine whether large subseafloor diapirs exist below active MVs, we try to detect the gravity contrast between the allochthonous materials and basin sediment. Gravity data were collected by research vessels over the area in 2012 2017. After corrections of drift and Etovos effects, absolute gravity, free-air and Bouguer gravity anomalies were calculated. The gravity data do not always show anomalies directly on MVs over the northern basin, thus suggesting that larger diapirs which have gravity contrast over a few milli-Gals do not exist below most of MVs in this basin. Instead, a large negative gravity anomaly is found at the northeastern end of the Kumano Basin. Localized positive anomalies exist along the KBEFZ in the area of theMV. The positive anomaly may suggest that an allochthonous high-density sediment body intrudes along the highly deformed, weak, fault zone.

  14. A review on contamination and emergency response actions in USSR, European countries and Japan in the reactor accident at Chernobyl

    International Nuclear Information System (INIS)

    Akaishi, Jun; Ohhata, Tsutomu

    1987-01-01

    The accident occurred in the Chernobyl No.4 reactor on April 26, 1986 became the largest accident of nuclear reactors so far as the quantity of release of radioactive substances was very much, and the wide area contamination over the whole Northern Hemisphere was brought about. Consequently, the revision over wide ranges, such as the desigh and operation of nuclear reactors and the response at the time of emergency, was to be urgently demanded. As to this accident, many reports have been already made. In this report, the contamination and the response carried out at the time of emergency including the state in Japan are mainly described. The contents of this report are based on the data sent from the international organizations, the results of measurement by the organizations in respective countries, the publication by USSR at the IAEA expert conference in August, 1986, and the data published in respective countries by research institutes. The state in respective countries after the accident, the radioactivity contamination due to the accident in USSR, European countries and Japan, the diffusion and move of radioactive substances, the countermeasures to the accident such as the estimation of exposure dose, scientific investigation, the evacuation of people and so on are reported. (Kako, I.)

  15. Japan 2003

    DEFF Research Database (Denmark)

    Ørstrup, Finn Rude; Hvass, Sven

    2003-01-01

    Kompendium udarbejdet til en studierejse til Japan  2003 Kunstakademiets Arkitektskole, Studieafdeling 10......Kompendium udarbejdet til en studierejse til Japan  2003 Kunstakademiets Arkitektskole, Studieafdeling 10...

  16. Central Gulf of Mexico lease sale draws weak industry response

    International Nuclear Information System (INIS)

    Koen, A.D.

    1992-01-01

    This paper reports that interest in oil and gas leases in the Gulf of Mexico continued spiraling downward at the latest Minerals Management Service offshore sale. Companies participating in Outer Continental Shelf Sale 139 last week in New Orleans offered 196 bids for 151 blocks in the central Gulf of Mexico. MMS offered 5,213 blocks for lease. The number of tracts receiving bids was the fewest at a central gulf lease sale since 114 tracts garnered high bids totaling $146.4 million at Sale 104 in April 1986. Apparent high bids in Sale 139 totaled $56,195,552, and all bids offered totaled just $65,300,864. Both bidding totals were the lowest in a Gulf of Mexico lease sale since MMS began area-wide gulf leasing at Sale 72 in May 1983. Only 64 of 93 qualified companies participated in Sale 139. Fifty-five companies offered apparent winning bids. By comparison, 123 companies at central gulf lease Sale 131 in March 1991 offered 637 bids totaling $320.5 million for 464 tracts. Apparent high bids last spring totaled $259.9 million. At central gulf lease Sale 123 in March 1990, high bids totaled $427.4 million for 538 tracts. In that sale, BP Exploration Inc. led all bidders, exposing $78 million in 79 high bids, including 60 for deepwater tracts. Since then, interest in deepwater tracts has waned in part because of sagging oil and gas prices as U.S. operators sought bigger prospects outside the U.S. Ironically, Sale 139 was dominated by the U.S. subsidiary of an Italian holding company

  17. [The relationship of quality of life (QOL) with physical fitness, competence and stress response in elderly in Japan].

    Science.gov (United States)

    Uemura, Shinichi; Machida, Kazuhiki

    2003-09-01

    In order to evaluate the relationship of quality of life (QOL) with physical fitness, competence and stress response in the elderly population in Japan, a cross sectional field survey of elderly subjects was conducted. This survey was taken in Naguri village, Saitama. The data collected included physical fitness, competence, stress response and QOL in addition to demographic variables. As for physical fitness indexes, grip strength (GS), single leg balance with eyes closed (SLB), bar grip ping reaction time (RT), trunk flexion (RF), ten-meter walking time (WT) and vital capacity (VC) were measured. The SF-36 was used for QOL assessment. A total of 120 elderly subjected participated to the survey. There were 42 males (73.5 +/- 5.74 years) and 78 females (74.2 +/- 6.17 years). The associations between physical health parameters in SF-36 and WT were highly significant: physical functioning (beta = -2.96, p fit indexes of the structural equation model describing the relationships among physical fitness, competence, stress response and QOL indicated excellent fit to the data with GFI = 0.95 and AGFI = 0.88. Stress response showed relatively stronger influence on QOL than physical fitness or competence. Although there were slight differences in degree of influence, physical fitness, stress response and competence were found to be clearly related to QOL in elderly subjects. To keep good QOL status, it is important to maintain good physical fitness and level of competence and to reduce stress response.

  18. Temporal and spatial variation of groundwater in quantity and quality in sand dune at coastal region, Kamisu city, central Japan.

    Science.gov (United States)

    Umei, Yohei; Tsujimura, Maki; Sakakibara, Koichi; Watanabe, Yasuto; Minema, Motomitsu

    2016-04-01

    The role of groundwater in integrated water management has become important in recent 10 years, though the surface water is the major source of drinking water in Japan. Especially, it is remarked that groundwater recharge changed due to land cover change under the anthropogenic and climatic condition factors. Therefore, we need to investigate temporal and spatial variation of groundwater in quantity and quality focusing on the change during recent 10-20 years in specific region. We performed research on groundwater level and quality in sand dune at coastal region facing Pacific Ocean, Kamisu city, Ibaraki Prefecture, which have been facing environmental issues, such as land cover change due to soil mining for construction and urbanization. We compared the present situation of groundwater with that in 2000 using existed data to clarify the change of groundwater from 2000 to 2015. The quality of water is dominantly characterized by Ca2+-HCO3- in both 2000 and 2015, and nitrate was not observed in 2015, though it was detected in some locations in 2000. This may be caused by improvement of the domestic wastewater treatment. The topography of groundwater table was in parallel with that of ground surface in 2015, same as that in 2000. However, a depletion of groundwater table was observed in higher elevation area in 2015 as compared with that in 2000, and this area corresponds to the locations where the land cover has changed due to soil mining and urbanization between 2015 and 2000. In the region of soil mining, the original soil is generally replaced by impermeable soil after mining, and this may cause a decrease of percolation and net groundwater recharge, thus the depletion of groundwater table occurred after the soil mining.

  19. Variations in airborne bacterial communities at high altitudes over the Noto Peninsula (Japan) in response to Asian dust events

    Science.gov (United States)

    Maki, Teruya; Hara, Kazutaka; Iwata, Ayumu; Lee, Kevin C.; Kawai, Kei; Kai, Kenji; Kobayashi, Fumihisa; Pointing, Stephen B.; Archer, Stephen; Hasegawa, Hiroshi; Iwasaka, Yasunobu

    2017-10-01

    Aerosol particles, including airborne microorganisms, are transported through the free troposphere from the Asian continental area to the downwind area in East Asia and can influence climate changes, ecosystem dynamics, and human health. However, the variations present in airborne bacterial communities in the free troposphere over downwind areas are poorly understood, and there are few studies that provide an in-depth examination of the effects of long-range transport of aerosols (natural and anthropogenic particles) on bacterial variations. In this study, the vertical distributions of airborne bacterial communities at high altitudes were investigated and the bacterial variations were compared between dust events and non-dust events.Aerosols were collected at three altitudes from ground level to the free troposphere (upper level: 3000 or 2500 m; middle level: 1200 or 500 m; and low level: 10 m) during Asian dust events and non-dust events over the Noto Peninsula, Japan, where westerly winds carry aerosols from the Asian continental areas. During Asian dust events, air masses at high altitudes were transported from the Asian continental area by westerly winds, and laser imaging detection and ranging (lidar) data indicated high concentrations of non-spherical particles, suggesting that dust-sand particles were transported from the central desert regions of Asia. The air samples collected during the dust events contained 10-100 times higher concentrations of microscopic fluorescent particles and optical particle counter (OPC) measured particles than in non-dust events. The air masses of non-dust events contained lower amounts of dust-sand particles. Additionally, some air samples showed relatively high levels of black carbon, which were likely transported from the Asian continental coasts. Moreover, during the dust events, microbial particles at altitudes of > 1200 m increased to the concentrations ranging from 1. 2 × 106 to 6. 6 × 106 particles m-3. In contrast

  20. Quantitative reconstruction of cross-sectional dimensions and hydrological parameters of gravelly fluvial channels developed in a forearc basin setting under a temperate climatic condition, central Japan

    Science.gov (United States)

    Shibata, Kenichiro; Adhiperdana, Billy G.; Ito, Makoto

    2018-01-01

    Reconstructions of the dimensions and hydrological features of ancient fluvial channels, such as bankfull depth, bankfull width, and water discharges, have used empirical equations developed from compiled data-sets, mainly from modern meandering rivers, in various tectonic and climatic settings. However, the application of the proposed empirical equations to an ancient fluvial succession should be carefully examined with respect to the tectonic and climatic settings of the objective deposits. In this study, we developed empirical relationships among the mean bankfull channel depth, bankfull channel depth, drainage area, bankfull channel width, mean discharge, and bankfull discharge using data from 24 observation sites of modern gravelly rivers in the Kanto region, central Japan. Some of the equations among these parameters are different from those proposed by previous studies. The discrepancies are considered to reflect tectonic and climatic settings of the present river systems, which are characterized by relatively steeper valley slope, active supply of volcaniclastic sediments, and seasonal precipitation in the Kanto region. The empirical relationships derived from the present study can be applied to modern and ancient gravelly fluvial channels with multiple and alternate bars, developed in convergent margin settings under a temperate climatic condition. The developed empirical equations were applied to a transgressive gravelly fluvial succession of the Paleogene Iwaki Formation, Northeast Japan as a case study. Stratigraphic thicknesses of bar deposits were used for estimation of the bankfull channel depth. In addition, some other geomorphological and hydrological parameters were calculated using the empirical equations developed by the present study. The results indicate that the Iwaki Formation fluvial deposits were formed by a fluvial system that was represented by the dimensions and discharges of channels similar to those of the middle to lower reaches of

  1. Integrating the Holocene tephrostratigraphy for East Asia using a high-resolution cryptotephra study from Lake Suigetsu (SG14 core), central Japan

    Science.gov (United States)

    McLean, Danielle; Albert, Paul G.; Nakagawa, Takeshi; Suzuki, Takehiko; Staff, Richard A.; Yamada, Keitaro; Kitaba, Ikuko; Haraguchi, Tsuyoshi; Kitagawa, Junko; Smith, Victoria C.; SG14 Project Members

    2018-03-01

    Tephra (volcanic ash) layers have the potential to synchronise disparate palaeoenvironmental archives on regional to hemispheric scales. Highly productive arc regions, like those in East Asia, offer a considerable number of widespread isochrons, but before records can be confidently correlated using these layers, a refined and integrated framework of these eruptive events is required. Here we present the first high-resolution Holocene cryptotephra study in East Asia, using the Lake Suigetsu sedimentary archive in central Japan. The Holocene tephrostratigraphy has been extended from four to twenty ash layers using cryptotephra extraction techniques, which integrates the deposits from explosive eruptions from North Korea/China, South Korea and along the Japanese arc. This Lake Suigetsu tephrostratigraphy is now the most comprehensive record of East Asian volcanism, and the linchpin site for correlating sequences across this region. Major element glass geochemical compositions are presented for the tephra layers in the sequence, which have been compared to proximal datasets to correlate them to their volcanic source and specific eruptions. This study has significantly extended the ash dispersal of many key Holocene marker layers, and has identified the first distal occurrence of isochrons from Ulleungdo and Changbaishan volcanoes. Utilising the high-precision Lake Suigetsu chronology, we are able to provide constrained eruption ages for the tephra layers, which can be transferred into other site-specific age models containing these markers. This new framework indicates that several isochrons stratigraphically bracket abrupt climate intervals in Japan, and could be used to precisely assess the regional and hemispheric synchronicity of these events.

  2. Long-term change of site response after the M W 9.0 Tohoku earthquake in Japan

    Science.gov (United States)

    Wu, Chunquan; Peng, Zhigang

    2012-12-01

    The recent M W 9.0 off the Pacific coast of Tohoku earthquake is the largest recorded earthquake in Japan's history. The Tohoku main shock and its aftershocks generated widespread strong shakings as large as ~3000 Gal along the east coast of Japan. Wu and Peng (2011) found clear drop of resonant frequency of up to 70% during the Tohoku main shock at 6 sites and correlation of resonance (peak) frequency and peak ground acceleration (PGA) during the main shock. Here we follow that study and systematically analyze long-term changes of material properties in the shallow crust from one year before to 5 months after the Tohoku main shock, using seismic data recorded by the Japanese Strong Motion Network KiK-Net. We use sliding window spectral ratios computed from a pair of surface and borehole stations to track the temporal changes in the site response of 6 sites. Our results show two stages of logarithmic recovery after a sharp drop of resonance frequency during the Tohoku main shock. The first stage is a rapid recovery within several hundred seconds to several hours, and the second stage is a slow recovery of more than five months. We also investigate whether the damage caused by the Tohoku main shock could make the near surface layers more susceptible to further damages, but we do not observe clear changes in susceptibility to further damage before and after the Tohoku main shock.

  3. Geothermal properties and groundwater flow estimated with a three-dimensional geological model in a late Pleistocene terrace area, central Japan

    Science.gov (United States)

    Funabiki, A.; Takemura, T.; Hamamoto, S.; Komatsu, T.

    2012-12-01

    of disturbance of the geothermal environment and groundwater flow caused by the use of GSHPs, therefore, would depend on the thickness of these gravels. Reference Funabiki, A., Nagoya, K., Kaneki, A., Uemura, K., Kurihara, M., Obara, H., Goto, A., Chiba, T., Naya, T., Ueki, T., and Takemura, T. (2011) Sedimentary facies and physical properties of the sediment core CRE-NUCHS-1 in Setagaya district, Tokyo, central Japan. Abstracts, The 118th Annual Meeting of theGeological Society of Japan. Acknowledgement This work was supported by the Core Research for Evolutional Science and Technology (CREST) program of the Japan Science and Technology Agency (JST).

  4. Three Kanto Earthquakes Inferred from the Tsunami Deposits and the Relative Sea Level Change in the Miura Peninsula, Central Japan

    Science.gov (United States)

    Kim, H.; Shimazaki, K.; Chiba, T.; Ishibe, T.; Okamura, M.; Matsuoka, H.; Tsuji, Y.; Satake, K.

    2010-12-01

    The Kanto earthquake is a great interplate earthquake caused by subduction of the Philippine Sea Plate beneath the Japan Island along the Sagami Trough. The 1923 Kanto earthquake (M=7.9) and the 1703 Kanto earthquake (M~8.0) are two of the most devastating earthquake those struck Tokyo Metropolitan area, respectively. These earthquakes brought large (~5 m) tsunami to the coast area and uplifted the Miura peninsula by ~1.4 m. The tide gauge station, moreover, records the subsidence during the interseismic period before and after the 1923 earthquake. Present study clarifies the past Kanto earthquake prior to the 1703 earthquake based on the sedimentary analysis in the Koajiro bay of the southern Miura Peninsula. The continuous samples of inner bay fine sediments were taken by the boring survey using 3-m-long geoslicer. Three layers of coarse sediments, T1, T2, and T3 units from top toward bottom, are observed in the bay sediments at almost all the sites. These units are composed of mixture of materials such as shell fragments, rock clasts and gravel, and some of units have eroded the lower fine sediments, indicating the event deposits by the strong traction flow. The grain sizes of the bay sediments are grading upward and abruptly become larger after the deposition of the T1, T2 and T3 units. Very little diatom is observed in these units, but the total number of diatoms increase in the bay sediments. The ratio of the marine planktonic species against the benthic species gradually rises from the lower part to the upper part in the bay sediment. In the tidal flat sediment, the freshwater planktonic species appear in place of the marine planktonic diatom. The changes of grain size and diatom species make a presumption that the sea depth suddenly becomes shallow by the event and deeper during the interseismic period. The T1, T2 and T3 units, thus, are correlated with the tsunami deposits conveyed by the Kanto earthquake. The T1 and T2 units are inferred to be the tsunami

  5. Hemagglutinating virus of Japan envelope (HVJ-E) can enhance the immune responses of swine immunized with killed PRRSV vaccine

    Energy Technology Data Exchange (ETDEWEB)

    Dai, Zhihong [State Key Laboratory of Agrobiotechnology, College of Veterinary Medicine, China Agricultural University, Beijing 100094 (China); China Institute of Veterinary Drug Control, Beijing 100081 (China); Zhang, Quan [College of Veterinary Medicine, Yangzhou University, Yangzhou 225009 (China); Wang, Zaishi [China Institute of Veterinary Drug Control, Beijing 100081 (China); Zhang, Zhongqiu [State Key Laboratory of Agrobiotechnology, College of Veterinary Medicine, China Agricultural University, Beijing 100094 (China); Veterinary Bureau, Ministry of Agriculture of the People' s Republic of China, Beijing 100125 (China); Guo, Pengju [Institute of Veterinary Medicine, Guangdong Academy of Agricultural Sciences, Guangdong 510640 (China); Zhao, Deming, E-mail: zhaodm@cau.edu.cn [State Key Laboratory of Agrobiotechnology, College of Veterinary Medicine, China Agricultural University, Beijing 100094 (China)

    2011-11-11

    Highlights: Black-Right-Pointing-Pointer We investigated the immunoadjuvant effects of HVJ-E on killed PRRSV vaccine. Black-Right-Pointing-Pointer HVJ-E enhanced the humoral and cellular responses of the piglets to PRRSV. Black-Right-Pointing-Pointer It is suggested that HVJ-E could be developed as a new-type adjuvant for mammals. -- Abstract: Porcine reproductive and respiratory syndrome virus (PRRSV) is an economically detrimental pig pathogen that causes significant losses for the pig industry. The immunostimulatory effects of hemagglutinating virus of Japan envelope (HVJ-E) in cancer therapy and the adjuvant efficacy of HVJ-E have been previously evaluated. The objective of this study was to investigate the adjuvant effects of HVJ-E on immunization with killed PRRSV vaccine, and to evaluate the protective effects of this immunization strategy against virulent PRRSV infection in piglets. Next, the PRRSV-specific antibody response, lymphocyte proliferation, PRRSV-specific IL-2, IL-10 and IFN-{gamma} production, and the overall protection efficacy were evaluated to assess the immune responses of the piglets. The results showed that the piglets inoculated simultaneously with killed PRRSV vaccine and HVJ-E had a significantly stronger immune response than those inoculated with killed PRRSV vaccine alone. Our results suggest that HVJ-E could be employed as an effective adjuvant to enhance the humoral and cellular responses of piglets to PRRSV.

  6. Typhoon Chataan off Japan

    Science.gov (United States)

    2002-01-01

    Slowly winding its way down, Typhoon Chataan had dropped to tropical storm status by Thursday, July 11, 2002, when this image from the Moderate Resolution Imaging Spectroradiometer (MODIS) was captured. In the image, the storm is located off the east coast of central Japan in the Pacific Ocean. The storm is much less organized than it was in the previous day's image. Through a gap in the clouds to the southwest of the storm's eye, Tokyo can be seen as a grayish cluster of pixels surrounding a small bay or inlet that protrudes into the island of Honshu. Credit: Image courtesy Jesse Allen, NASA Earth Observatory; data provided by the MODIS Land Rapid Response Team

  7. The spatial variation of initial 87Sr/86Sr ratios in the Toki granite, Central Japan. Implications for the intrusion and cooling processes of a granitic pluton

    International Nuclear Information System (INIS)

    Yuguchi, Takashi; Tsuruta, Tadahiko; Hama, Katsuhiro; Nishiyama, Tadao

    2013-01-01

    The spatial variation in initial 87 Sr/ 86 Sr ratios (SrI) in the Toki granite, Central Japan, shows heterogeneity ranging from 0.708942 to 0.710069, which provides information on the intrusion and cooling processes of plutons. The Toki granite has three mineralogy-based rock facies: muscovite-biotite granite (MBG), hornblende-biotite granite (HBG) and biotite granite (BG). Large SrI values were found to be distributed at the western margin (west MBG) and the lithologically central region (central BG), while small SrI values were found at the northeast margin (northeast MBG). Regions with high and low Sr concentrations were also found in the Toki granite. In the Sr-rich samples, SrI (0.708942-0.709789) increases with 100/Sr (0.7-1.5). This geochemical trend extends towards the country sedimentary rocks of the Mino Terrane, which can be interpreted to result from assimilation and fractional crystallization (AFC) between the original granitic magma and the Mino sedimentary rocks. The SrI values in the Sr-rich regions show a correlation with the Alumina Saturation Index (ASI). In particular, the west MBG, with large SrI values, is classified as a peraluminous granitoid with large ASI, suggesting that the western margin of the pluton was strongly affected by assimilation during the intrusion process. The Sr-poor samples are present both in the central BG, with large SrI values, and in the northeast MBG, with small SrI values. The Sr-poor samples have small ASI and large differentiation indices, indicating that the central BG and the northeast MBG were generated either by different AFC process with different amounts of contaminants or by the intrusion and fractionation of different source magma with different SrI values. Overall, the geochemical spatial variations found in the Toki granite can be explained by various degrees of assimilation and fractional crystallization in the magma chamber and/or multi-stage intrusions with different degrees of crystallization of

  8. Taxonomic notes on the ground beetles in the genus Trephionus Bates, 1883 from central Honshu, Japan (Coleoptera, Carabidae, Sphodrini, Synuchina).

    Science.gov (United States)

    Sasakawa, Kôji; Itô, Hirotarô

    2018-01-01

    Trephionus Bates, 1883, a Japanese endemic genus in the subtribe Synuchina (Coleoptera, Carabidae, Sphodrini), is revised taxonomically based mainly on the shape of the endophallus, a membranous inner sac everted from the aedeagus of the male genitalia. Three known species from central Honshu, T. kinoshitai Habu, 1954; T. shibataianus Habu, 1978; and T. babai Habu, 1978, are re-defined based on this genital character, and five new species are described from the region: T. cylindriphallus Sasakawa, sp . n ., T. niumontanus Sasakawa, sp . n ., T. inexpectatus Sasakawa & Itô, sp . n ., T. abiba Sasakawa & Itô, sp . n ., and T. bifidilobatus Sasakawa & Itô, sp . n . The observed interspecies differences in endophallus morphology are discussed in terms of the species-level phylogeny and genus-level taxonomy of Trephionus .

  9. Taxonomic notes on the ground beetles in the genus Trephionus Bates, 1883 from central Honshu, Japan (Coleoptera, Carabidae, Sphodrini, Synuchina

    Directory of Open Access Journals (Sweden)

    Kôji Sasakawa

    2018-03-01

    Full Text Available Trephionus Bates, 1883, a Japanese endemic genus in the subtribe Synuchina (Coleoptera, Carabidae, Sphodrini, is revised taxonomically based mainly on the shape of the endophallus, a membranous inner sac everted from the aedeagus of the male genitalia. Three known species from central Honshu, T. kinoshitai Habu, 1954; T. shibataianus Habu, 1978; and T. babai Habu, 1978, are re-defined based on this genital character, and five new species are described from the region: T. cylindriphallus Sasakawa, sp. n., T. niumontanus Sasakawa, sp. n., T. inexpectatus Sasakawa & Itô, sp. n., T. abiba Sasakawa & Itô, sp. n., and T. bifidilobatus Sasakawa & Itô, sp. n. The observed interspecies differences in endophallus morphology are discussed in terms of the species-level phylogeny and genus-level taxonomy of Trephionus.

  10. K-Ar age of molybdenum mineralization in the east-central Kitakami Mountains, northern Honshu, Japan

    International Nuclear Information System (INIS)

    Ishihara, Shunso; Shibata, Ken; Uchiumi, Shigeru

    1989-01-01

    Three K-Ar ages were determined on rocks and minerals from the mineralized areas in the east-central part of the Kitakami Cretaceous granitic terrain, where a Paleogene mineralization age was reported recently on molybdenite by the Re-Os method. The present result showed an early Cretaceous age of 114±4 Ma for the same molybdenite deposit. A rather large discrepancy was found between the Re-Os ages for molybdenite and the K-Ar and Rb-Sr ages for silicate minerals from the same ore deposits of Mesozoic-Cenozoic ages in the Circum-Pacific region, indicating that the Re-Os method needs further examination. (author)

  11. Evaluation of energy responses for neutron dose-equivalent meters made in Japan

    International Nuclear Information System (INIS)

    Saegusa, J.; Yoshizawa, M.; Tanimura, Y.; Yoshida, M.; Yamano, T.; Nakaoka, H.

    2004-01-01

    Energy responses of three types of Japanese neutron dose-equivalent (DE) meters were evaluated by Monte Carlo simulations and measurements. The energy responses were evaluated for thermal neutrons, monoenergetic neutrons with energies up to 15.2 MeV, and also for neutrons from such radionuclide sources as 252 Cf and 241 Am-Be. The calculated results were corroborated with the measured ones. The angular dependence of the response and the DE response were also evaluated. As a result, reliable energy responses were obtained by careful simulations of the proportional counter, moderator and absorber of the DE meters. Furthermore, the relationship between pressure of counting gas and response of the DE meter was discussed. By using the obtained responses, relations between predicted readings of the DE meters and true DE values were studied for various workplace spectra

  12. Behavioral Response in the Immediate Aftermath of Shaking: Earthquakes in Christchurch and Wellington, New Zealand, and Hitachi, Japan

    Directory of Open Access Journals (Sweden)

    Ihnji Jon

    2016-11-01

    Full Text Available This study examines people’s response actions in the first 30 min after shaking stopped following earthquakes in Christchurch and Wellington, New Zealand, and Hitachi, Japan. Data collected from 257 respondents in Christchurch, 332 respondents in Hitachi, and 204 respondents in Wellington revealed notable similarities in some response actions immediately after the shaking stopped. In all four events, people were most likely to contact family members and seek additional information about the situation. However, there were notable differences among events in the frequency of resuming previous activities. Actions taken in the first 30 min were weakly related to: demographic variables, earthquake experience, contextual variables, and actions taken during the shaking, but were significantly related to perceived shaking intensity, risk perception and affective responses to the shaking, and damage/infrastructure disruption. These results have important implications for future research and practice because they identify promising avenues for emergency managers to communicate seismic risks and appropriate responses to risk area populations.

  13. Responses to emergencies in Mexico and Central America

    International Nuclear Information System (INIS)

    Diaz, E.F.

    1986-01-01

    Radiation emergencies have two main aspects: radiation safety, which concerns control of the radiation source, and, more importantly, health effects, which entail diagnoses, treatment, and rehabilitation. The physician participates directly in a radiation emergency because he or she is the professional who knows best the human body and the methodology to re-establish health. However, because these types of incidents are infrequent, many physicians are poorly prepared to deal with such emergencies. Two main aspects of emergency response plans are: (1) prevention, including public education for behavior and planning for appropriate response; and (2) application, including prophylactic measures, assessing the extent of exposure and contamination, controlling public anxiety, and managing and treating the victims

  14. Microelectronics in Japan

    Science.gov (United States)

    Boulton, William R.

    1995-02-01

    The purpose of this JTEC study is to evaluate Japan's electronic manufacturing and packaging capabilities within the context of global economic competition. To carry out this study, the JTEC panel evaluated the framework of the Japanese consumer electronics industry and various technological and organizational factors that are likely to determine who will win and lose in the marketplace. This study begins with a brief overview of the electronics industry, especially as it operates in Japan today. Succeeding chapters examine the electronics infrastructure in Japan and take an in-depth look at the central issues of product development in order to identify those parameters that will determine future directions for electronic packaging technologies.

  15. RESPONSE OF THE U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES IN PROTECTING CIVILIAN AMERICANS IN JAPAN DURING THE FUKUSHIMA NUCLEAR CRISIS.

    Science.gov (United States)

    Simon, Steven L; Coleman, C Norman; Noska, Michael A; Bowman, Thomas

    2012-05-01

    Following the earthquake and tsunami in northern Japan on 11 March 2011, and the ensuing damage to the Fukushima Daiichi nuclear power plant complex, a request by the U.S. Ambassador to Japan to the U.S. Department of Health and Human Services (DHHS) Assistant Secretary for Preparedness and Response (ASPR) resulted in deployment of a five-person team of subject matter experts to the U.S. Embassy. The primary purpose of the deployment was to provide the U.S. Embassy in Tokyo with guidance on health and medical issues related to potential radiation exposure of U.S. citizens in Japan, including employees of the U.S. Department of State at consulates in Japan and American citizens living in or visiting Japan. At the request of the Government of Japan, the deployed health team also assisted Japanese experts in their public health response to the radiation incident. Over a three-week period in Japan and continuing for weeks after their return to the U.S., the team provided expertise in the areas of medical and radiation oncology, health physics, assessment of radiation dose and cancer risk, particularly to U.S. citizens living in Tokyo and the surrounding areas, food and water contamination and the acceptable limits, countermeasures to exposure such as potassium iodide (KI), the use of KI and an offered donation from the United States, evacuation and re-entry issues, and health/emergency-related communication strategies. This paper describes the various strategies used and observations made by the DHHS team during the first two months after the Fukushima crisis began.

  16. Correlation and stratigraphic eruption age of the pyroclastic flow deposits and wide spread volcanic ashes intercalated in the Pliocene-Pleistocene strata, central Japan

    International Nuclear Information System (INIS)

    Nagahashi, Yoshitaka; Satoguchi, Yasufumi; Yoshikawa, Shusaku

    2000-01-01

    Three pyroclastic flow deposits in the Takayama and Omine area, central Honshu, are correlated to the distal widespread volcanic ashes intercalated in the Plio-Pleistocene boundary strata in central Japan. The correlation is based on these stratigraphic relationships, facies, magnetostratigraphy, petrographic properties such as mineral assemblage, refractive index and chemical composition of the volcanic glasses and orthopyroxene. As the result of these correlation, the eruption age of the proximal pyroclastic flow deposits have become clear. And precise correlation between proximal eruption units and distal depositional units is now possible. Ho-Kd 39 Tephra erupted at about 1.76 Ma, forming a co-ignimbrite ash, which deposited in the Kanto sedimentary basin. Eb-Fukuda Tephra erupted at about 1.75 Ma, and distal volcaniclastic deposit sedimented in the Kinki, Niigata and Kanto sedimentary basins. The eruptional and depositional phase are divided into the stage 1, stage 2 (early), stage 2 (late) and stage 3. Stage 1 is phreato-plinian type eruption phase, forming distal ash fall deposit. Stage 2 (early) is plinian pumice fall, intra-plinian pyroclastic flow and plinian pumice fall eruption phase, forming distal ash fall. Stage 2 (late) is final eruptional phase of the biggest pyroclastic flow of the Eb-Fukuda Tephra, forming a co-ignimbrite ash fall. Stage 3 is resedimented stage after the end of the explosive eruption. It is notable that resedimented volcaniclastic deposit reached Osaka sedimentary basin 300 km away from the eruption center. Om-SK110 Tephra erupted at about 1.65 Ma, divided into the stage 1, stage 2 and stage 3. Stage 1 is eruption phase of the plinian pumice fall and first pyroclastic flow. Stage 2 is pauses in eruption activity. Stage 3 is second pyroclastic flow phase, it is inferred that the pyroclastic flow of the stage 3 directly entered the Niigata sedimentary basin and simultaneously formed a co-ignimbrite ash. (author)

  17. Plutonic rocks in the Mineoka-Setogawa ophiolitic mélange, central Japan: Fragments of middle to lower crust of the Izu-Bonin-Mariana Arc?

    Science.gov (United States)

    Ichiyama, Yuji; Ito, Hisatoshi; Hokanishi, Natsumi; Tamura, Akihiro; Arai, Shoji

    2017-06-01

    A Paleogene accretionary complex, the Mineoka-Setogawa Belt, is distributed around the Izu Collision Zone, central Japan. Plutonic rocks of gabbro, diorite and tonalite compositions are included as fragments and dykes in an ophiolitic mélange in this belt. Zircon U-Pb dating of the plutonic rocks indicates that they were formed at ca. 35 Ma simultaneously. These ages are consistent with Eocene-Oligocene tholeiite and calc-alkaline arc magmatism in the Izu-Bonin-Mariana (IBM) Arc and exclude several previous models for the origin of the Mineoka-Setogawa ophiolitic rocks. The geochemical characteristics of these plutonic rocks are similar to those of the Eocene-Oligocene IBM tholeiite and calc-alkaline volcanic rocks as well as to the accreted middle crust of the IBM Arc, the Tanzawa Plutonic Complex. Moreover, their lithology is consistent with those of the middle and lower crust of the IBM Arc estimated from the seismic velocity structure. These lines of evidence strongly indicate that the plutonic rocks in the Mineoka-Setogawa ophiolitic mélange are fragments of the middle to lower crust of the IBM Arc. Additionally, the presence of the Mineoka-Setogawa intermediate to felsic plutonic rocks supports the hypothesis that intermediate magma can form continental crust in intra-oceanic arcs.

  18. Three-dimensional cooling pattern of a granitic pluton 2. The study of deuteric sub-solidus reactions in the Toki granite, Central Japan

    International Nuclear Information System (INIS)

    Yuguchi, Takashi; Tsuruta, Tadahiko; Nishiyama, Tadao

    2011-01-01

    Petrographical studies examining the development and variations of sub-solidus reactions recorded in the Toki granite represent the three-dimensional cooling pattern of this zoned pluton in Central Japan. Samples collected from 19 boreholes in the Toki granite show characteristics indicative of spatial variations in the extent of the sub-solidus reactions. Exsolution coarsening has produced microperthite, including albite-rich lamellae, in this pluton, while deuteric coarsening has resulted in the formation of patchperthite, myrmekite, and the reaction rim. The extent of the deuteric coarsening reactions can be evaluated from the width and spacing of the albite-rich patch in patchperthite and from the thickness of myrmekite and the reaction rim. The width, spacing, and thickness of these textural features increase systematically with elevation; they also increase gradually in the horizontal inward direction in the western part of the pluton but not in the eastern part of the pluton. The systematic variations in textural development indicate that the Toki granite cooled effectively from the roof and from the western margin during the deuteric coarsening stage. The deuteric coarsening may have occurred at temperatures below 500°C, as indicated by ternary feldspar thermometry. (author)

  19. Spatial Upscaling of Soil Respiration under a Complex Canopy Structure in an Old‐Growth Deciduous Forest, Central Japan

    Directory of Open Access Journals (Sweden)

    Vilanee Suchewaboripont

    2017-01-01

    Full Text Available The structural complexity, especially canopy and gap structure, of old‐growth forests affects the spatial variation of soil respiration (Rs. Without considering this variation, the upscaling of Rs from field measurements to the forest site will be biased. The present study examined responses of Rs to soil temperature (Ts and water content (W in canopy and gap areas, developed the best fit modelof Rs and used the unique spatial patterns of Rs and crown closure to upscale chamber measurements to the site scale in an old‐growth beech‐oak forest. Rs increased with an increase in Ts in both gap and canopy areas, but the effect of W on Rs was different between the two areas. The generalized linear model (GLM analysis identified that an empirical model of Rs with thecoupling of Ts and W was better than an exponential model of Rs with only Ts. Moreover, because of different responses of Rs to W between canopy and gap areas, it was necessary to estimate Rs in these areas separately. Consequently, combining the spatial patterns of Rs and the crown closure could allow upscaling of Rs from chamber‐based measurements to the whole site in the present study.

  20. Thermal Regime of A Deep Temperate Lake and Its Response to Climate Change: Lake Kuttara, Japan

    Directory of Open Access Journals (Sweden)

    Kazuhisa A. Chikita

    2018-02-01

    Full Text Available A deep temperate lake, Lake Kuttara, Hokkaido, Japan (148 m deep at maximum was completely ice-covered every winter in the 20th century. However, ice-free conditions of the lake over winter occurred three times in the 21st century, which is probably due to global warming. In order to understand how thermal regime of the lake responds to climate change, a change in lake mean water temperature from the heat storage change was calculated by integrating observed water temperature over water depths and by numerical calculation of heat budget components based on hydrometeorological data. As a result, a temporal variation of lake mean water temperature from the heat budget calculation was very reasonable to that from the observed water temperature (determination coefficient R2 = 0.969. The lowest lake mean temperature for non-freeze was then evaluated at −1.87 °C, referring to the zero level at 6.80 °C. The 1978–2017 data at a meteorological station near Kuttara indicated that there are significant (less than 5% level long-term trends for air temperature (+0.024 °C/year and wind speed (−0.010 m/s/year. In order to evaluate the effects of climate change on freeze-up patterns, a sensitivity analysis was carried out for the calculated lake mean water temperature. It is noted that, after two decades, the lake could be ice-free once per every two years.

  1. Stigma in response to mental disorders: a comparison of Australia and Japan

    Science.gov (United States)

    Griffiths, Kathleen M; Nakane, Yoshibumi; Christensen, Helen; Yoshioka, Kumiko; Jorm, Anthony F; Nakane, Hideyuki

    2006-01-01

    Background There are few national or cross-cultural studies of the stigma associated with mental disorders. Australia and Japan have different systems of psychiatric health care, and distinct differences in cultural values, but enjoy similar standards of living. This study seeks to compare the nature and extent of stigma among the public in the two countries. Methods A household survey of the public was conducted in each country using similar methodologies. The Australian study comprised a national survey of 3998 adults aged over 18 years. The Japanese survey involved 2000 adults aged 20 to 69 from 25 regional sites distributed across the country. Interviewees reported their personal attitudes (personal stigma, social distance) and perceptions of the attitudes of others (perceived stigma, perceived discrimination) in the community with respect to four case vignettes. These vignettes described a person with: depression; depression with suicidal ideation; early schizophrenia; and chronic schizophrenia. Results Personal stigma and social distance were typically greater among the Japanese than the Australian public whereas the reverse was true with respect to the perception of the attitudes and discriminatory behaviour of others. In both countries, personal stigma was significantly greater than perceived stigma. The public in both countries showed evidence of greater social distance, greater personal stigma and greater perceived stigma for schizophrenia (particularly in its chronic form) than for depression. There was little evidence of a difference in stigma for depression with and without suicide for either country. However, social distance was greater for chronic compared to early schizophrenia for the Australian public. Conclusion Stigmatising attitudes were common in both countries, but negative attitudes were greater among the Japanese than the Australian public. The results suggest that there is a need to implement national public awareness interventions

  2. Stigma in response to mental disorders: a comparison of Australia and Japan

    Directory of Open Access Journals (Sweden)

    Jorm Anthony F

    2006-05-01

    Full Text Available Abstract Background There are few national or cross-cultural studies of the stigma associated with mental disorders. Australia and Japan have different systems of psychiatric health care, and distinct differences in cultural values, but enjoy similar standards of living. This study seeks to compare the nature and extent of stigma among the public in the two countries. Methods A household survey of the public was conducted in each country using similar methodologies. The Australian study comprised a national survey of 3998 adults aged over 18 years. The Japanese survey involved 2000 adults aged 20 to 69 from 25 regional sites distributed across the country. Interviewees reported their personal attitudes (personal stigma, social distance and perceptions of the attitudes of others (perceived stigma, perceived discrimination in the community with respect to four case vignettes. These vignettes described a person with: depression; depression with suicidal ideation; early schizophrenia; and chronic schizophrenia. Results Personal stigma and social distance were typically greater among the Japanese than the Australian public whereas the reverse was true with respect to the perception of the attitudes and discriminatory behaviour of others. In both countries, personal stigma was significantly greater than perceived stigma. The public in both countries showed evidence of greater social distance, greater personal stigma and greater perceived stigma for schizophrenia (particularly in its chronic form than for depression. There was little evidence of a difference in stigma for depression with and without suicide for either country. However, social distance was greater for chronic compared to early schizophrenia for the Australian public. Conclusion Stigmatising attitudes were common in both countries, but negative attitudes were greater among the Japanese than the Australian public. The results suggest that there is a need to implement national public

  3. Disseminated tuberculosis of the central nervous system responsive to rifabutin.

    Science.gov (United States)

    Riva, M; Crippa, S; Di Palma, F; Gerini, A M; Soresi, E; Scoccia, S

    1990-04-01

    Multiple cerebral tuberculomas are now very rare. We report the case of a young man with an 8-month history of headache, febricula and abscess of the left tibiotarsal joint, which was found to contain mycobacterium tuberculosis. Chest X-rays revealed miliariform dissemination to both lungs while CT and MR brain scans revealed numerous small nodules, especially in the posterior cranial fossa. Despite anti-tuberculosis therapy the patient developed a right pyramidal hemisyndrome and intracranial hypertension. The inclusion of rifabutin in the treatment schedule was followed by rapid improvement and a year later the patient was in good health and free from cerebral and pulmonary lesions. The interest of the case lies in the multiplicity of sites of the TB process in a non immunodepressed patient, the dissemination to the CNS without meningeal involvement, the resistance to standard antimycobacterials and the swift response to rifabutin.

  4. Implications of the World Trade Center Health Program (WTCHP) for the public health response to the Great East Japan Earthquake

    International Nuclear Information System (INIS)

    Crane, Michael A.; Cho, Hyunje G.; Landrigan, Phillip J.

    2014-01-01

    The attacks on the World Trade Center (WTC) on September 11, 2001 resulted in a serious burden of physical and mental illness for the 50,000 rescue workers that responded to 9/11 as well as the 400,000 residents and workers in the surrounding areas of New York City. The Zadroga Act of 2010 established the WTC Health Program (WTCHP) to provide monitoring and treatment of WTC exposure-related conditions and health surveillance for the responder and survivor populations. Several reports have highlighted the applicability of insights gained from the WTCHP to the public health response to the Great East Japan Earthquake. Optimal exposure monitoring processes and attention to the welfare of vulnerable exposed sub-groups are critical aspects of the response to both incidents. The ongoing mental health care concerns of 9/11 patients accentuate the need for accessible and appropriately skilled mental health care in Fukushima. Active efforts to demonstrate transparency and to promote community involvement in the public health response will be highly important in establishing successful long-term monitoring and treatment programs for the exposed populations in Fukushima. (author)

  5. A Preliminary Analysis on Empirical Attenuation of Absolute Velocity Response Spectra (1 to 10s) in Japan

    Science.gov (United States)

    Dhakal, Y. P.; Kunugi, T.; Suzuki, W.; Aoi, S.

    2013-12-01

    The Mw 9.1 Tohoku-oki earthquake caused strong shakings of super high rise and high rise buildings constructed on deep sedimentary basins in Japan. Many people felt difficulty in moving inside the high rise buildings even on the Osaka basin located at distances as far as 800 km from the epicentral area. Several empirical equations are proposed to estimate the peak ground motions and absolute acceleration response spectra applicable mainly within 300 to 500km from the source area. On the other hand, Japan Meteorological Agency has recently proposed four classes of absolute velocity response spectra as suitable indices to qualitatively describe the intensity of long-period ground motions based on the observed earthquake records, human experiences, and actual damages that occurred in the high rise and super high rise buildings. The empirical prediction equations have been used in disaster mitigation planning as well as earthquake early warning. In this study, we discuss the results of our preliminary analysis on attenuation relation of absolute velocity response spectra calculated from the observed strong motion records including those from the Mw 9.1 Tohoku-oki earthquake using simple regression models with various model parameters. We used earthquakes, having Mw 6.5 or greater, and focal depths shallower than 50km, which occurred in and around Japanese archipelago. We selected those earthquakes for which the good quality records are available over 50 observation sites combined from K-NET and KiK-net. After a visual inspection on approximately 21,000 three component records from 36 earthquakes, we used about 15,000 good quality records in the period range of 1 to 10s within the hypocentral distance (R) of 800km. We performed regression analyses assuming the following five regression models. (1) log10Y (T) = c+ aMw - log10R - bR (2) log10Y (T) = c+ aMw - log10R - bR +gS (3) log10Y (T) = c+ aMw - log10R - bR + hD (4) log10Y (T) = c+ aMw - log10R - bR +gS +hD (5) log10Y

  6. Evaluation of electric and magnetic field monitoring of Miyake-jima volcano (Central Japan). 1995-1999

    Energy Technology Data Exchange (ETDEWEB)

    Sasai, Y.; Uyeshima, M.; Watanabe, H.; Takahashi, Y. [Tokyo Univ., Tokyo (Japan). Earthquake Research Institute; Zlotniki, J.; Yvetot, P. [Universite Blaise Pascal, Observatoire de Physique du Globe de Clermont-Ferrand, Clermont-Ferrand (France); Nishida, Y. [Hokkaido University, Graduate School of Science, Sapporo (Japan); Tanaka, Y. [Kyoto University, Graduate School of Science, Volcano Research Center (Japan)

    2001-04-01

    south around the central-southern area of the island from September 1996 to June 1998. The source of the anomaly, i.e. a thermally demagnetized area, was suggested to lie beneath the southern wall of Hatcho-Taira caldera. This is the first observation which indicates heating of the volcano besides the after-effects of the 1983 eruption. Except for the two locally anomalous stations, the geomagnetic total intensity on Miyake-jima island shows a gradual decrease for the past five years. This fact is probably related to the increasing pressure of the magma reservoir at depth as supported by the on-going inflation of the volcano via GPS observations.

  7. Comparison of Community Response to Road Traffic Noise in Japan and SWEDEN—PART i: Outline of Surveys and DOSE-RESPONSE Relationships

    Science.gov (United States)

    SATO, T.; YANO, T.; BJÖRKMAN, M.; RYLANDER, R.

    2002-02-01

    To investigate cross-cultural differences in the community response to road traffic noise, social surveys were conducted in Gothenburg, Sweden, and Kumamoto and Sapporo, Japan, using the same questionnaire and noise measurement method. Typical residential areas with detached houses and apartments were selected as the target areas in each city. The questionnaire comprised 40 questions relating to environmental, housing and personal factors. The key questions concerned annoyance caused by road traffic noise. The total numbers of respondents were 1142 in Gothenburg, 837 in Kumamoto and 780 in Sapporo. The response rates were 68·8, 69·3 and 57·5% respectively. After the questionnaires were completed, noise measurements were made in each area. Community responses were compared on the basis of the dose-response relationships. There were no systematic differences between community responses in Sapporo and Kumamoto, which have the same culture. People living in detached houses in Gothenburg were more annoyed by the same road traffic noise than the people living in Japanese cities. There were no systematic differences among the three cities with regard to activity disturbances indoors, but significant disturbance of activities and resting in gardens or on balconies was noted in Gothenburg. The difference in activity disturbance was due to the differences between lifestyles in the two countries. People living in detached houses were more annoyed by the house vibration caused by road traffic than those living in apartments and people were annoyed by the exhaust from road traffic to the same extent as noise.

  8. Developing a Fracture Model of the Granite Rocks Around the Research Tunnel at the Mizunami Underground Research Laboratory in Central Japan

    Science.gov (United States)

    Kalinina, E.; Hadgu, T.; Wang, Y.

    2017-12-01

    The Mizunami Underground Research Laboratory (MIU) is located in Tono area in Central Japan. It is operated by the Japan Atomic Energy Agency (JAEA) with the main purpose of providing scientific basis for the research and development of technologies needed for deep geological disposal of radioactive waste in fractured crystalline rocks. The current work is focused on the research and experiments in the tunnel located at 500 m depth. The data collected in the tunnel and exploratory boreholes were shared with the participants of the DEvelopment of COupled models and their VALidation against EXperiments (DECOVALEX), an international research and model comparison collaboration. This study describes the development of the fracture model representing granite rocks around the research tunnel. The model domain is 100x150x100m with the main experimental part of the tunnel, Closure Test Drift, located approximately in the center. The major input data were the fracture traces measured on the tunnel walls (total of 2,023 fractures), fractures observed in the horizontal borehole parallel to the tunnel, and the packer tests conducted in this borehole and one vertical borehole located within the modeling domain. 78 fractures (the ones with the inflow) in the tunnel were incorporated in the development of the fracture model. Fracture size was derived from the fracture trace analysis. It was shown that the fracture radius followed lognormal distributions. Fracture transmissivity was estimated from an analytical solution of inflow into the tunnel through an individual fracture and the total measured inflow into the tunnel. 16 fractures were incorporated in the model along the horizontal borehole. The packer test data in the different well intervals were used to estimate the range in fracture transmissivity. A relationship between the fracture transmissivity and fracture radius was developed. The fractures in the tunnel and borehole were used to derive fracture orientation and

  9. Vascular plant species richness along environmental gradients in a cool temperate to sub-alpine mountainous zone in central Japan.

    Science.gov (United States)

    Tsujino, Riyou; Yumoto, Takakazu

    2013-03-01

    In order to clarify how vegetation types change along the environmental gradients in a cool temperate to sub-alpine mountainous zone and the determinant factors that define plant species richness, we established 360 plots (each 4 × 10 m) within which the vegetation type, species richness, elevation, topographic position index (TPI), slope inclination, and ground light index (GLI) of the natural vegetation were surveyed. Mean elevation, TPI, slope inclination, and GLI differed across vegetation types. Tree species richness was negatively correlated with elevation, whereas fern and herb species richness were positively correlated. Tree species richness was greater in the upper slope area than the lower slope area, whereas fern and herb species richness were greater in the lower slope area. Ferns and trees species richness were smaller in the open canopy, whereas herb species richness was greater in the open canopy. Vegetation types were determined firstly by elevation and secondary by topographic configurations, such as topographic position, and slope inclination. Elevation and topography were the most important factors affecting plant richness, but the most influential variables differed among plant life-form groups. Moreover, the species richness responses to these environmental gradients greatly differed among ferns, herbs, and trees.

  10. Emergency response of Fukushima Daini Nuclear Power Station during the Great East Japan Earthquake and its lessons

    International Nuclear Information System (INIS)

    Kawamura, Shinichi

    2016-01-01

    At the time of the occurrence of the Great East Japan Earthquake, Fukushima Daini Nuclear Power Station (hereinafter, Fukushima Daini) was operating four units of BWRS-5 type plants with an output of 1,100 MWe/unit. Among these plants, No. 1, 2, and 4 Units lost all the functions of heat removal equipment of reactors affected by tsunami. However, ad-hoc activities such as the exchange of submerged motors and temporary power installation allowed the recovery of residual heat removal (RHR) system, leading to a success in cold shutdown. This is a success story more than expectation in dealing with emergency situations, but not necessarily all of the correspondences were successfully carried out, leaving some problems. As lessons, the following are pointed out: (1) confirmation of the damage situation of the site and setting of priority rank of recovery, (2) securement of the means that do not depend on initial on-site activities, and (3) possession at the site of the skills of emergency restoration, equipment diagnostic technology, and repair technology. With reflecting lessons and challenges in these correspondences, Tokyo Electric Power Company is working to improve the accident response capability of the organization including Kashiwazaki-Kariwa Nuclear Power Station. As an example of effort of emergency response capability strengthening, there is an application of the US Incident Management System (IMS). The company is continuously making efforts for improving safety through training. (A.O.)

  11. Analysis of emergency response to fukushima nuclear accident in Japan and suggestions for China's nuclear emergency management

    International Nuclear Information System (INIS)

    Li Wei; Ding Qihua; Wu Haosong

    2014-01-01

    On March 11, 2011, the Fukushima Dai-ichi Nuclear Power Station of the Tokyo Electric Power Company ('TEPCO') was hit and damaged by a magnitude 9 earthquake and accompanying tsunami. The accident is determined to be of the highest rating on the International Nuclear Event Scale. The Government of Japan and TEPCO have taken emergency response actions on-site and off-site at the accident. It became clear through the investigation that the accident had been initiated on the occasion of a natural disaster of an earthquake and tsunami, but there have been various complex problems behind this very serious and large scale accident. For an example, the then-available accident preventive measures and disaster preparedness of TEPCO were insufficient against tsunami and severe accidents; inadequate TEPCO emergency responses to the accident at the site were also identified. The accident rang the alarm for the nuclear safety of nuclear power plants. It also taught us a great of lessons in nuclear emergency management. (authors)

  12. [Introduction of the psychoprophylactic method and its influence on the prenatal care program for institutional parturition in Japan: the practice in the Central Hospital of Maternity of the Japanese Red Cross Society and Oomori Red Cross Hospital, 1953-1964].

    Science.gov (United States)

    Fujihara, Satoko; Tsukisawa, Miyoko

    2014-03-01

    The psychoprophylactic method is one of the methods for providing 'painless childbirth without drugs' and was invented by applying I. Pavlov's theory of higher nervous activity. In 1951, it was adopted as a national policy in the Union of Soviet Socialist Republics. This method was then introduced in the People's Republic of China in 1952. In 1953, it was brought to Japan by Masatomo SUGAI, an obstetrician, and was introduced into the Central Hospital of Maternity of the Japanese Red Cross Society with the support of the director, Naotarou KUJI. The practice of this method by the research team, which consisted of the obstetricians and midwives of the Central Hospital of Maternity of the Japanese Red Cross Society and Oomori Red Cross Hospital, resulted in the initiation and characterization of the prenatal care program to encourage the autonomy of the pregnant women for normal parturition in the institutions of Japan.

  13. Influence of human activities on the activity patterns of Japanese sika deer (Cervus nippon) and wild boar (Sus scrofa) in Central Japan

    NARCIS (Netherlands)

    Doormaal, van N.; Ohashi, H.; Koike, S.; Kaji, K.

    2015-01-01

    Human ageing and population decline in Japan are causing agricultural field abandonment and providing new habitats for Japanese sika deer and wild boar. These species have expanded their distribution and increased in abundance across Japan and are causing increased agricultural damage. Effective

  14. Roles of National and Local Governments and the Dietetic Association in Nutrition Assistance Response to Natural Disasters: Systems and Experiences in Japan and the USA.

    Science.gov (United States)

    Sudo, Noriko

    2015-01-01

    In the first half of this symposium, the disaster response system in Japan will be introduced. The ultimate aim of nutrition assistance is to keep people in disaster areas healthy. This is a task for the Ministry of Health, Labour and Welfare and the health departments of prefectural governments. Our first speaker, Dr. Yasuhiro Kanatani, National Institute of Public Health, will briefly overview the disaster response system in Japan and its related laws. He will also mention how the Ministry responded to the Great East Japan Earthquake. In the second presentation, I will play one chapter of DVD that we released in last September. In that chapter, Ms. Makiko Sawaguchi, a registered dietitian working for a public health center in the area affected by the Great East Japan Earthquake, talks about her experience in supporting disaster victims. As an employee of Iwate Prefectural Government, she helped affected municipal governments and coordinated outside support. One type of outside support was registered dietitians dispatched by the Japan Dietetic Association (JDA). Dr. Nobuyo Tsuboyama-Kasaoka will report what those dietitians did in the affected areas. She will also explain the aim and training of the JDA-Disaster Assistance Team. Provision of food is essential in nutrition assistance. This is a task for the Ministry of Agriculture, Forestry and Fisheries. Our fourth speaker, Mr. Kunihiro Doi, analyzed the government procurement data and will discuss the limitations of government emergency food supplies and lessons learned from the Great East Japan Earthquake. As for the systems and experiences in the US, we invited Ms. Toni Abernathy from the Office of Emergency Management, Food and Nutrition Service (FNS), United States Department of Agriculture.

  15. Application of UAV-SfM photogrammetry and aerial LiDAR to a disastrous flood: multitemporal topographic measurement of a newly formed crevasse splay of the Kinu River, central Japan

    OpenAIRE

    Izumida, Atsuto; Uchiyama, Shoichiro; Sugai, Toshihiko

    2017-01-01

    Geomorphic impacts of a disastrous crevasse splay that formed in September 2015 and its post-formation modifications were quantitatively documented by using multitemporal, high-definition digital surface models (DSMs) of an inhabited and cultivated floodplain of the Kinu River, central Japan. The DSMs used were based on pre-flood (resolution, 2 m) and post-flood (resolution, 1 m) aerial light detection and ranging (LiDAR) data from January 2007 and September 2015, respectively, ...

  16. Morphological and light-absorption characteristics of individual BC particles collected in an urban seaside area at Tokaimura, eastern central Japan

    International Nuclear Information System (INIS)

    Fu Fengfu; Watanabe, Kazuo; Shinohara, Nobuo; Xu Xueqin; Xu Liangjun; Akagi, Tasuku

    2008-01-01

    To observe surface morphology and light-absorption property of different black carbon (BC) particles, different-sized aerosols were collected in Tokaimura (36.27 o N, 140.36 o E), an urban seaside area of eastern central Japan, using a high-volume Andersen type sampler during a whole year (Jan. to Dec. in 2004). The morphology of individual BC particle separated from different-sized aerosols was observed with Scanning Electron Microscope with Energy Dispersive X-ray Spectrometer (SEM-EDX) and four types of morphology were observed: 50 nm spherical particles, micrometer-sized plates with homogeneous surfaces, micrometer-sized spherical particles with homogeneous surfaces and micrometer-sized spherical particles with small holes on surfaces. The light-absorption property of BC particles with different morphology has been determined by infrared spectrometry (IRS) with a photoacoustic technique in a region of 400-4000 wavenumbers (cm -1 ). All morphology BC particles showed a strong light-absorption during 500-3000 wavenumbers (cm -1 ) with two strong broad peaks in 750-1100 and 1200-2200 wavenumbers (cm -1 ), implying that all morphology BC particles can absorb a significant part of thermal infrared emitted from the earth (wavelength 4000-50,000 nm). The seasonal variation and the size-distribution of aerosols and its chemical components (e.g. C, Na, Cl, NH 4 + , NO 3 - , SO 4 2- , Al, Ca, Mg and Fe) were also measured in this study. More than 55% of non-inorganic carbon (OC + BC) in the atmosphere was detected in the aerosols with a size smaller than 1.1 μm and the concentration of non-inorganic carbon in the atmosphere showed only a faint variation during a whole year, although the concentrations of total aerosols and its chemical components exhibited a distinct variation

  17. Morphological and light-absorption characteristics of individual BC particles collected in an urban seaside area at Tokaimura, eastern central Japan.

    Science.gov (United States)

    Fu, Feng Fu; Watanabe, Kazuo; Shinohara, Nobuo; Xu, Xueqin; Xu, Liangjun; Akagi, Tasuku

    2008-04-15

    To observe surface morphology and light-absorption property of different black carbon (BC) particles, different-sized aerosols were collected in Tokaimura (36.27 degrees N, 140.36 degrees E), an urban seaside area of eastern central Japan, using a high-volume Andersen type sampler during a whole year (Jan. to Dec. in 2004). The morphology of individual BC particle separated from different-sized aerosols was observed with Scanning Electron Microscope with Energy Dispersive X-ray Spectrometer (SEM-EDX) and four types of morphology were observed: 50 nm spherical particles, micrometer-sized plates with homogeneous surfaces, micrometer-sized spherical particles with homogeneous surfaces and micrometer-sized spherical particles with small holes on surfaces. The light-absorption property of BC particles with different morphology has been determined by infrared spectrometry (IRS) with a photoacoustic technique in a region of 400-4000 wavenumbers (cm(-1)). All morphology BC particles showed a strong light-absorption during 500-3000 wavenumbers (cm(-1)) with two strong broad peaks in 750-1100 and 1200-2200 wavenumbers (cm(-1)), implying that all morphology BC particles can absorb a significant part of thermal infrared emitted from the earth (wavelength 4000-50,000 nm). The seasonal variation and the size-distribution of aerosols and its chemical components (e.g. C, Na, Cl, NH(4)(+), NO(3)(-), SO(4)(2-), Al, Ca, Mg and Fe) were also measured in this study. More than 55% of non-inorganic carbon (OC+BC) in the atmosphere was detected in the aerosols with a size smaller than 1.1 microm and the concentration of non-inorganic carbon in the atmosphere showed only a faint variation during a whole year, although the concentrations of total aerosols and its chemical components exhibited a distinct variation.

  18. Calcareous nannofossil biostratigraphy and geochronology of Neogene trench-slope cover sediments in the south Boso Peninsula, central Japan: Implications for the development of a shallow accretionary complex

    Science.gov (United States)

    Chiyonobu, Shun; Yamamoto, Yuzuru; Saito, Saneatsu

    2017-07-01

    The geological structure and calcareous nannofossil biostratigraphy of the Middle to Late Miocene trench-slope succession in the southern Boso Peninsula, central Japan, were examined to obtain chronological constraints on the accretion and formation of the trench-slope architecture. As a result, trench-slope cover sediments (Kinone and Amatsu Formations) are clearly distinguishable from the Early Miocene Hota accretionary complex (Hota Group). The Hota accretionary complex was deposited below the carbonate compensation depth (CCD) and was affected by intense shearing, forming an east-west trending and south-verging fold and thrust belt. In contrast, the trench-slope cover sediments basically have a homoclinal dip, except at the northern rim where they are bounded by fault contact. They contain many species of calcareous nannofossils and foraminifers, which are indicative of their depositional environment above the CCD, and they show shallowing-upward sedimentary structures. Biostratigraphy revealed that the depositional age of the trench-slope sediments is ca. 15-5.5 Ma, suggesting that there is an approximately 2 myr hiatus beween the Miura Group and the underlying accretionary prism. Based on these results, the age of accretion of the Hota Group is inferred to be between ca. 17-15 Ma, and the group is covered by trench-slope sediments overlain on it after ca. 15 Ma. The timing of accretion and the age of the trench-slope basin tend to be younger southward of the Boso Peninsula. The accretionary system of the Boso Peninsula apparently developed in two stages, in the Middle Miocene and in the Late Miocene to Pliocene.

  19. Estimation of the spatiotemporal evolution of slow slip events in the Tokai region, central Japan, during 1994 - 2016 using GNSS data

    Science.gov (United States)

    Sakaue, H.; Nishimura, T.; Fukuda, J.; Kato, T.

    2017-12-01

    In the Tokai region, central Japan, the long-term slow slip events (L-SSEs) observed on the subducting Philippine Sea Plate (PSP) from 2000 to 2005 and since 2013. Moreover, many short-term slow slip events (S-SSEs) have been observed in the Tokai region since 1996. Sakaue et al. (2017) reported that the spatiotemporal evolution of an L-SSE and S-SSEs on the PSP beneath the Tokai region from 2013 to 2015. This study is probably the first case that migration of slip for S-SSE (Mw GPS Research) in the Tokai region. It is well known that GNSS time series have many systematic signals that do not result from SSEs. These systematic signals include, for example, seasonal variations, cosiesmic and post-seismic deformation of the 2004 off Southeast Kii Peninsula eqrthquake and the 2011 Tohoku-oki earthquake (Mw. 9.0), crustal deformation of volcanic activity on Miyake-jima island and so on. After removing these systematic signals, we applied a modified Network Inversion Filter (NIF) [Fukuda et al., 2008]. The original NIF [Segall & Matthews, 1997] assumes a constant hyperparameter for the temporal smoothing of slip rates and thus often results in oversmoothing of slip rates. The modified NIF assumes a time-variable hyperparameter, so that changes in slip rates are effectively extracted from GNSS time series.The results indicate that not only the spatiotemporal evolutions of the 2000 Tokai L-SSE and the 2013 L-SSE but also the spatiotemporal evolution of S-SSEs are estimated. We will present a comparison of the spatiotemporal evolutions between the 2000 Tokai L-SSE and the 2013 L-SSE and possible dependence of the occurrence style of S-SSEs on the occurrence of the L-SSEs.

  20. Results of primary central nervous system lymphoma treated by radiation and chemotherapy. Retrospective analysis of twelve institutions in the Tokai district of Japan, 1995-1999

    International Nuclear Information System (INIS)

    Kawamura, Toshiki; Ishiguchi, Tsuneo; Shibamoto, Yuta

    2006-01-01

    We analyzed the therapeutic results and prognostic factors of 46 primary central nervous system lymphoma (PCNSL) patients who were treated at twelve institutions in the Tokai district of Japan between 1995 and 1999. We compared the results with those of a Japanese nationwide survey performed in the past. We sent each institution a questionnaire about the state of patients' disease, pathological type, method and doses of radiotherapy, regimen and intensity of chemotherapy, and patients' prognoses. The range of patients' ages was 33 to 93 years (median, 61 years). Thirty-one were men and 15 were women. The most prevalent histology was diffuse large B cell type (33 patients). We used the Kaplan-Meier method to calculate the survival rate and Cox's proportional hazards model to analyze the prognostic factors. The five-year cumulative survival rate was 25%, and the median survival time was 22.7 months. The five-year disease-free survival rate was 23%. In monovariate analysis, patients who were both younger than 60 years old and had a World Health Organization (WHO) performance status (PS) score equal to or less than 2 showed a better survival rate. Furthermore, the patients receiving systemic chemotherapy showed a significantly better local control rate. In addition, patients who received systemic chemotherapy achieved a higher complete remission rate than those not receiving it. However, no factors that significantly influenced survival rate were identified in multivariate analysis. We demonstrated that the therapeutic outcome of PCNSL patients has recently improved. In particular, patients with good PS showed better local control than those with poor PS. However, we could not identify any significant prognostic factors in PCNSL patients. (author)

  1. Preferred-rupture propagation to the hangingwall of the shallow part of the out-of-sequence thrust: Ishido Fault in Boso Peninsula, central Japan

    Science.gov (United States)

    Yamamoto, Y.; Fukuyama, M.; Ujiie, K.; Hirose, T.; Hamada, Y.; Kitamura, M.; Kamiya, N.

    2016-12-01

    Although earthquake ruptures in shallow portion of plate boundary have recently been identified (e.g. Tohoku, Nankai, etc.), their mechanisms why the shallow portion of plate boundary composed mainly of clay minerals can accumulate strain and make seismic slip are under controversial. An ancient out-of-sequence thrust which divided the early and late Miocene accretionary complexes in the Boso Peninsula, central Japan records rupture propagation to the shallow portion of accretionary prism (The fault core is composed of black-colored thin (The former is characterized by homogeneous glassy matrix including fragments of quartz/feldspar, submicron-sized Fe-rich spherules, and vesicles. Based on the mineralogy of the host rock and EDS analyses of matrices, origin of the pseudotachylite was apparently frictional melting of smectite containing Fe. Fe-rich spherules formed by rapid cooling of pseudotachylite. On the other hand, overturned fault-related drag fold developed in the footwall, within about 30 m. Although some Riedel sheared normal faults developed in the overturned footwall, no other brittle deformations were identified. These occurrences imply coexistence of low- and high-speed slips along the same thrust fault. The whole-rock major and trace elemental analyses using XRF and ICP-MS show that mudstone in the hangingwall has similar chemical composition to those of pseudotachylite and fluidized fault gouge with REE enriched patterns, whereas the footwall has different chemical characteristics with relatively flat REE pattern and low LOI. Therefore, the protolith of pseudotachylite and fluidized fault gouge is mudstone in the hangingwall. These data imply that rupture propagation preferably occurred in the hangingwall along the fault zone. The footwall was also deformed apparently during slow-slip deformation leading to formation of the overturn, whereas only the hangingwall, just side of the fault zone, slipped under high-speed shear.

  2. Seismic Structure of the Oceanic Plate Entering the Central Part of the Japan Trench Obtained from Ocean-Bottom Seismic Data

    Science.gov (United States)

    Ohira, A.; Kodaira, S.; Fujie, G.; No, T.; Nakamura, Y.; Miura, S.

    2017-12-01

    In trench-outer rise regions, the normal faults develop due to the bending of the incoming plate, which cause numerous normal-faulting earthquakes and systematic structural variations toward trenches. In addition to the effects on the bend-related normal fault, structural variations which are interpreted to be attributed to pseudofaults, a fracture zone, and petit-spot volcanic activities are observed in the oceanic plate entering the central part of the Japan Trench, off Miyagi. In May-June 2017, to understand detail structural variations and systematic structural changes of the oceanic plate toward the trench, we conducted an active-source seismic survey off Miyagi using R/V Kaimei, a new research vessel of JAMSTEC. Along a 100 km-long seismic profile which is approximately perpendicular to the trench axis, we deployed 40 ocean-bottom seismometers at intervals of 2 km and fired a large airgun array (total volume 10,600 cubic inches) with 100 m shooting intervals. Multi-channel seismic reflection data were also collected along the profile. On OBS records we observed refractions from the sedimentary layer and the oceanic crust (Pg), wide-angle reflections from the crust-mantle boundary (PmP), and refractions from the uppermost mantle (Pn). Pg is typically observed clearly at near offsets (approximately 20 km) but it highly attenuates at far offsets (> 20 km). A triplication of Pg-PmP-Pn with strong amplitudes is observed at ranges from 30 km to 60 km offsets. Pn is typically weak and its apparent velocity is approximately 8 km/sec. High attenuation of Pg and weak Pn may indicate the complex crustal structure related to petit-spot volcanic activities and/or a fracture zone, which are recognized in bathymetry data around the profile.

  3. Neural Hyperactivity of the Central Auditory System in Response to Peripheral Damage

    Directory of Open Access Journals (Sweden)

    Yi Zhao

    2016-01-01

    Full Text Available It is increasingly appreciated that cochlear pathology is accompanied by adaptive responses in the central auditory system. The cause of cochlear pathology varies widely, and it seems that few commonalities can be drawn. In fact, despite intricate internal neuroplasticity and diverse external symptoms, several classical injury models provide a feasible path to locate responses to different peripheral cochlear lesions. In these cases, hair cell damage may lead to considerable hyperactivity in the central auditory pathways, mediated by a reduction in inhibition, which may underlie some clinical symptoms associated with hearing loss, such as tinnitus. Homeostatic plasticity, the most discussed and acknowledged mechanism in recent years, is most likely responsible for excited central activity following cochlear damage.

  4. Central and peripheral components of short latency vestibular responses in the chicken

    Science.gov (United States)

    Nazareth, A. M.; Jones, T. A.

    1998-01-01

    Far-field recordings of short latency vestibular responses to pulsed cranial translation are composed of a series of positive and negative peaks occurring within 10 ms following stimulus onset. In the bird, these vestibular evoked potentials (VsEPs) can be recorded noninvasively and have been shown in the chicken and quail to depend strictly upon the activation of the vestibular component of the eighth nerve. The utility of the VsEP in the study of vestibular systems is dependent upon a clear understanding of the neural sources of response components. The primary aim of the current research in the chicken was to critically test the hypotheses that 1) responses are generated by both peripheral and central neurons and 2) peaks P1 and N1 originate from first order vestibular neurons, whereas later waves primarily depend on activity in higher order neurons. The principal strategy used here was to surgically isolate the eighth nerve as it enters the brainstem. Interruption of primary afferents of the eighth nerve in the brainstem substantially reduced or eliminated peaks beyond P2, whereas P1 and N1 were generally spared. Surgical sections that spared vestibular pathways had little effect on responses. The degree of change in response components beyond N1 was correlated with the extent of damage to central vestibular relays. These findings support the conclusion that responses are produced by both peripheral and central elements of the vestibular system. Further, response peaks later than N1 appear to be dependent upon central relays, whereas P1 and N1 reflect activity of the peripheral nerve. These findings clarify the roles of peripheral and central neurons in the generation of vestibular evoked potentials and provide the basis for a more useful and detailed interpretation of data from vestibular response testing.

  5. Fighting Brick with Brick: Chikazumi Jōkan and Buddhism’s Response to Christian Space in Imperial Japan

    Directory of Open Access Journals (Sweden)

    Garrett Washington

    2013-03-01

    Full Text Available In 1915, with the support of Jōdo Shinshū (True Pure Land Buddhism’s Higashi Honganji sect and dozens of private Buddhist donors, Buddhist priest Chikazumi Jōkan erected a new, one-of-a-kind Buddhist meeting hall in Tokyo, the Kyūdō Kaikan. Chikazumi conceived of the building as a clear and deliberate spatial challenge to the crowded Protestant churches and lecture halls of turn-of-the-twentieth-century Tokyo. He chose prominent Western-style architect Takeda Goichi (1872–1938, rather than a traditional Japanese shrine or temple carpenter, to design it. The new building, in tandem with the adjacent Kyūdō Gakusha (Salvation Dormitory that Chikazumi established in 1902, spoke to, and significantly impacted, the socio-moral, intellectual, and religious life of hundreds of young Tokyoites. These two buildings represented a response to Protestant Christianity’s popularity and relevance like no other in imperial Japan. In order to achieve the religious evangelism and suprasectarian reform that he envisioned for Buddhism, Chikazumi proved willing to apply observations made in the West and appropriate practical Western Christian architectural features. Through an analysis of drawings, photographs, periodicals, institutional records, and other sources, this article tells the story of the rare fusion of opposites as Chikazumi equipped Buddhism to compete with Protestantism for the attention and devotion of the educated elite.

  6. Japan's approach to monetary policy

    OpenAIRE

    Giovanni P. Olivei

    2002-01-01

    The goal of monetary policy as conducted by the Bank of Japan is to contribute to the sound development of the national economy through the pursuit of price stability. The objective of price stability, however, is not precisely defined as it has been for other central banks. Following the implementation of the new Bank of Japan Law in 1998, the monetary policy framework is characterized by central bank independence, the primacy of the price stability objective, instrument independence, and po...

  7. Neutralization antibody response to booster/priming immunization with new equine influenza vaccine in Japan.

    Science.gov (United States)

    Yamanaka, Takashi; Nemoto, Manabu; Bannai, Hiroshi; Tsujimura, Koji; Matsumura, Tomio; Kokado, Hiroshi; Gildea, Sarah; Cullinane, Ann

    2018-03-02

    Equine influenza (EI) vaccine has been widely used. However, the causative EI virus (H3N8) undergoes continuous antigenic drift, and the vaccine strains must be periodically reviewed and if necessary, updated to maintain vaccine efficacy against circulating viruses. In 2016, the Japanese vaccine was updated by replacing the old viruses with the Florida sub-lineage Clade (Fc) 2 virus, A/equine/Yokohama/aq13/2010 (Y10). We investigated the virus neutralization (VN) antibody response to Fc2 viruses currently circulating in Europe, after booster or primary immunization with the new vaccine. These European viruses have the amino acid substitution A144V or I179V of the hemagglutinin. In horses that had previously received a primary course and bi-annual boosters with the old vaccine booster, immunization with the updated vaccine increased the VN antibody levels against the European Fc2 viruses as well as Y10. There were no significant differences in the VN titers against Y10 and the Fc2 viruses with A144V or I179V substitution in horses that had received a primary course of the updated vaccine. However, a mixed primary course where the first dose was the old vaccine and the second dose was the updated vaccine, reduced VN titers against the European viruses compared to that against Y10. In summary, the new vaccine affords horses protective level of VN titers against the Fc2 viruses carrying A144V or I179V substitution, but our results suggest that the combination of the old and new vaccines for primary immunization would not be optimum.

  8. An inter-religious humanitarian response in the Central African Republic

    Directory of Open Access Journals (Sweden)

    Catherine Mahony

    2014-11-01

    Full Text Available Inter-religious action has played a key role in ensuring that social cohesion and inter-religious mediation remain on the international agenda in relation to response in the Central African Republic, where people’s faith is an integral part of their identity but where it has been manipulated in a horrific way.

  9. Phosphorus Response and Fertilizer Recommendations for Wheat Grown on Nitisols in the Central Ethiopian Highlands

    NARCIS (Netherlands)

    Agegnehu, Getachew; Nelson, Paul N.; Bird, Michael I.; Beek, van Christy

    2015-01-01

    The provision of farmers with proper and balanced fertilizer recommendations is becoming increasingly important, for reasons of crop productivity, food security, and sustainability. Phosphorus (P) response trials with wheat were conducted on Nitisols at 14 sites in the central Ethiopian highlands

  10. Glucose intolerance induced by blockade of central FGF receptors is linked to an acute stress response

    Directory of Open Access Journals (Sweden)

    Jennifer M. Rojas

    2015-08-01

    Conclusions: The effect of acute inhibition of central FGFR signaling to impair glucose tolerance likely involves a stress response associated with pronounced, but transient, sympathoadrenal activation and an associated reduction of insulin secretion. Whether this effect is a true consequence of FGFR blockade or involves an off-target effect of the FGFR inhibitor requires additional study.

  11. Location of early aftershocks of the 2004 Mid-Niigata Prefecture Earthquake (M = 6.8) in central Japan using seismogram envelopes as templates

    Science.gov (United States)

    Kosuga, M.

    2013-12-01

    The location of early aftershocks is very important to obtain information of mainshock fault, however, it is often difficult due to the long-lasting coda wave of mainshock and successive occurrence of afterrshocks. To overcome this difficulty, we developed a method of location using seismogram envelopes as templates, and applied the method to the early aftershock sequence of the 2004 Mid-Niigata Prefecture (Chuetsu) Earthquake (M = 6.8) in central Japan. The location method composes of three processes. The first process is the calculation of cross-correlation coefficients between a continuous (target) and template envelopes. We prepare envelopes by taking the logarithm of root-mean-squared amplitude of band-pass filtered seismograms. We perform the calculation by shifting the time window to obtain a set of cross-correlation values for each template. The second process is the event detection (selection of template) and magnitude estimate. We search for the events in descending order of cross-correlation in a time window excluding the dead times around the previously detected events. Magnitude is calculated by the amplitude ratio of target and template envelopes. The third process is the relative event location to the selected template. We applied this method to the Chuetsu earthquake, a large inland earthquake with extensive aftershock activity. The number of detected events depends on the number of templates, frequency range, and the threshold value of cross-correlation. We set the threshold as 0.5 by referring to the histogram of cross-correlation. During a period of one-hour from the mainshock, we could detect more events than the JMA catalog. The location of events is generally near the catalog location. Though we should improve the methods of relative location and magnitude estimate, we conclude that the proposed method works adequately even just after the mainshock of large inland earthquake. Acknowledgement: We thank JMA, NIED, and the University of Tokyo for

  12. Transformation of juvenile Izu-Bonin-Mariana oceanic arc into mature continental crust: An example from the Neogene Izu collision zone granitoid plutons, Central Japan

    Science.gov (United States)

    Saito, Satoshi; Tani, Kenichiro

    2017-04-01

    Granitic rocks (sensulato) are major constituents of upper continental crust. Recent reviews reveal that the average composition of Phanerozoic upper continental crust is granodioritic. Although oceanic arcs are regarded as a site producing continental crust material in an oceanic setting, intermediate to felsic igneous rocks occurring in modern oceanic arcs are dominantly tonalitic to trondhjemitic in composition and have lower incompatible element contents than the average upper continental crust. Therefore, juvenile oceanic arcs require additional processes in order to get transformed into mature continental crust enriched in incompatible elements. Neogene granitoid plutons are widely exposed in the Izu Collision Zone in central Japan, where the northern end of the Izu-Bonin-Mariana (IBM) arc (juvenile oceanic arc) has been colliding with the Honshu arc (mature island arc) since Middle Miocene. The plutons in this area are composed of various types of granitoids ranging from tonalite to trondhjemite, granodiorite, monzogranite and granite. Three main granitoid plutons are distributed in this area: Tanzawa plutonic complex, Kofu granitic complex, and Kaikomagatake granitoid pluton. Tanzawa plutonic complex is dominantly composed of tonalite and trondhjemite and characterized by low concentration of incompatible elements and shows geochemical similarity with modern juvenile oceanic arcs. In contrast, Kofu granitic complex and Kaikomagatake granitoid pluton consists mainly of granodiorite, monzogranite and granite and their incompatible element abundances are comparable to the average upper continental crust. Previous petrogenetic studies on these plutons suggested that (1) the Tanzawa plutonic complex formed by lower crustal anatexis of juvenile basaltic rocks occurring in the IBM arc, (2) the Kofu granitic complex formed by anatexis of 'hybrid lower crust' comprising of both basaltic rocks of the IBM arc and metasedimentary rocks of the Honshu arc, and (3) the

  13. Seasonal variations of {sup 14}C and δ{sup 13}C for cave drip waters in Ryugashi Cave, Shizuoka Prefecture, central Japan

    Energy Technology Data Exchange (ETDEWEB)

    Minami, Masayo, E-mail: minami@nendai.nagoya-u.ac.jp [Center for Chronological Research, Nagoya University, Nagoya 464-8602 (Japan); Kato, Tomomi [Graduate School of Environmental Studies, Nagoya University, Nagoya 464-8601 (Japan); Horikawa, Keiji [Department of Environmental Biology and Chemistry, Toyama University, Toyama 930-8555 (Japan); Nakamura, Toshio [Center for Chronological Research, Nagoya University, Nagoya 464-8602 (Japan)

    2015-11-01

    Speleothem {sup 14}C has recently emerged as a potentially powerful proxy for hydrology changes in comparison with atmospheric {sup 14}C calibration curve, rather than as a direct dating tool, apart from a time marker using bomb peak of {sup 14}C. Some possible causes for the relationship between speleothem {sup 14}C content (or dead carbon fraction: DCF) and karst hydrology have been proposed, such as changes in temperature, precipitation, drip water flow dynamics, cave air ventilation, soil air pCO{sub 2}. In this study, we investigated seasonal variation in {sup 14}C and δ{sup 13}C of drip water in Ryugashi Cave, Shizuoka Prefecture, central Japan, to examine the causes of the {sup 14}C and δ{sup 13}C variations in a speleothem. The results show that different {sup 14}C concentrations and δ{sup 13}C values of drip water from the Ryugashi Cave, were exhibited at different sites of the Caves No. 1, No. 3, and No. 4, which have different temperature, air pCO{sub 2}, and flow paths. Further, the {sup 14}C and δ{sup 13}C of drip waters showed seasonal variations at all sites, which were lower in fall and winter, and higher in spring and summer, though the extent of the variations was different among the sites. The {sup 14}C in drip waters tended to be correlated with the drip rates: {sup 14}C tended to be higher in drip waters with higher drip rates, and also correlated with rainfall amount around the Ryugashi Cave, especially for the drip waters in Cave No. 3, which are considered to have simpler flow paths. The increase in rainfall amount could bring the increase in drip rate of drip water, and then the decrease in interaction between solution and karst, resulting in {sup 14}C increase (DCF decrease) in drip water. Accordingly, the reconstruction of precipitation could be performed using {sup 14}C variation in a speleothem formed by drip water with simple flow dynamics.

  14. Initiation process of the Mw 6.2 central Tottori, Japan, earthquake on October 21, 2016: Stress transfer due to its largest foreshock of Mw 4.1

    Science.gov (United States)

    Noda, S.; Ellsworth, W. L.

    2017-12-01

    On October 21, 2016, a strike-slip earthquake with Mw 6.2 occurred in the central Tottori prefecture, Japan. It was preceded by a foreshock sequence that began with a Mw 4.1 event, the largest earthquake for the sequence, and lasted about two hours. According to the JMA catalog, the largest foreshock had a similar focal mechanism as the mainshock and was located in the immediate vicinity of the mainshock hypocenter. The goal of this study is to understand the relationship between the foreshock and the initial rupture of the mainshock. We first determine the relative hypocenter distance between the foreshock and mainshock using the P-wave onsets on Hi-net station records. The initiation points of the two events are likely about 100 m apart according to the current results, but could be closer. Within the location uncertainty, they might either be coplanar or on subparallel planes. Next, we obtain the slip-history models from a kinematic inversion method using empirical Green's functions derived from other foreshocks with M 2.2 - 2.4. The Mw 4.1 foreshock and Mw 6.2 mainshock started in a similar way until approximately 0.2 s after their onsets. For the foreshock, the rapid growth stage completed by 0.2 s even though the rupture propagation continued for 0.4 - 0.5 s longer (note that 0.2 s is significantly shorter than the typical source duration of a Mw 4.1 earthquake). On the other hand, the mainshock rupture continued to grow rapidly after 0.2 s. The comparison between the relative hypocenter locations and the slip models shows that the mainshock nucleated within the area strongly effected by both static and dynamic stress changes created by the foreshock. We also find that the mainshock initially propagated away from the foreshock hypocenter. We consider that the stress transfer process is a key to understand the mainshock nucleation as well as its rupture growth process.

  15. Distribution of mountain wetlands and their response to Holocene climate change in the Hachimantai Volcanic Groups, northeastern Japan

    Science.gov (United States)

    Sasaki, N.; Sugai, T.

    2017-12-01

    Mountain wetlands, natural peatlands or lakes, with narrow catchment areas need abundant water supply and topography retaining water because of unstable water condition. This study examines wetland distribution with a focus on topography and snow accumulation, and discuss wetland evolution responding to Holocene climate change in the Hachimantai Volcanic Group, northeastern Japan, where the East Asian winter monsoon brings heavier snow and where has many wetlands of varied origin: crater lakes and wetlands in nivation hollows on original volcanic surfaces, and wetlands in depressions formed by landslides. We identified and classified wetlands using aerial photographs and 5-m and 10-m digital elevation models. Wetlands on the original volcanic surfaces tend to be concentrated under the small scarps with much snow or on saddles of the mountain ridge where snowmelt from surrounding slopes maintains a moist environment. More lake type wetlands are formed in the saddle than in the snowdrifts. That may represent that the saddles can correct more recharge water and may be a more suitable topographic condition for wetland formation and endurance. On the contrary, wetlands on landslides lie at the foot of the scarps where spring water can be abundantly supplied, regardless of snow accumulation. We used lithological analysis, 14C dating, tephra age data, and carbon contents of wetland cores to compare the evolution of wetlands, one (the Oyachi wetland) within a huge landslide and three (the Appi Highland wetlands) outside of a landslide area. We suggest that the evolution of the wetland in the landslide is primarily influenced by landslide movements and stream dissection rather than climate change. In the Appi Highland wetlands, peatlands appeared much later and at the almost same time in the Medieval Warm Period. We suggest that the development of mountain wetlands outside of landslide areas is primarily related to climate changes. Responsiveness of mountain wetlands to

  16. Clinical and radiological characteristics of central pulmonary adenocarcinoma: a comparison with central squamous cell carcinoma and small cell lung cancer and the impact on treatment response

    Directory of Open Access Journals (Sweden)

    Wang Z

    2018-05-01

    Full Text Available Zhe Wang,1,2 Minghuan Li,2 Yong Huang,3 Li Ma,3 Hui Zhu,2 Li Kong,2 Jinming Yu2 1School of Medicine, Shandong University, Jinan, Shandong, China; 2Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Jinan, Shandong, China; 3Department of Radiology, Shandong Cancer Hospital Affiliated to Shandong University, Jinan, Shandong, China Purpose: The proportion of central pulmonary adenocarcinoma (ADC in central-type lung cancer has been gradually increasing due to the overall increasing incidence of pulmonary ADC. But the clinical and radiological characteristics of central ADCs remain unclear. In this study, we compared the clinical and radiological characteristics of central ADCs with those of small cell lung cancers (SCLCs and squamous cell carcinomas (SQCCs and investigated the impact of these characteristics on patients’ treatment response. Patients and methods: The medical records of 302 consecutive patients with central lung cancer from July 2014 to September 2016 were retrospectively reviewed. There were 99 patients with ADC, 95 with SQCC and 108 with SCLC. Computed tomography images were interpreted by two radiologists. Treatment response was determined by Response Evaluation Criteria In Solid Tumors 1.1. Results: Univariate analyses found that younger age, female sex, no history of smoking, higher levels of carcinoembryonic antigen (CEA, contralateral hilum lymphadenopathy, contralateral lung metastasis, pleural nodules and pleural metastasis to the interlobular fissure were significantly correlated with central ADC. Multivariate logistic regression analyses revealed that compared with central SQCC, female sex, younger age, no history of smoking, higher levels of CEA and contralateral hilum lymphadenopathy were the significantly independent indicators of central pulmonary ADC. Furthermore, compared with central SCLC, younger age, higher levels of CEA and cytokeratin 19 fragment (Cyfra21-1, lower

  17. Response to state comments on the revised draft North Central Regional characterization reports for the Crystalline Repository Project

    International Nuclear Information System (INIS)

    1985-08-01

    The purpose of this document is to respond to the comments received from the states of the North Central Region on the revised draft North Central Regional Characterization Reports (RCRs). The responses in this document indicate the manner in which the suggestions or comments received have been considered in modifying the revised draft North Central RCRs. Both general comments related to the overall Crystalline Repository Project (CRP) and comments on specific sections of the RCRs are addressed. This document responds to North Central State comments on both the revised draft North Central Regional Geologic Characterization Report (RGCR) and the revised draft North Central Regional Environmental Characterization Report (RECR)

  18. Clinical features and early treatment response of central nervous system involvement in childhood acute lymphoblastic leukemia

    DEFF Research Database (Denmark)

    Levinsen, Mette; Taskinen, Mervi; Abrahamsson, Jonas

    2014-01-01

    BACKGROUND: Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) remains a therapeutic challenge. PROCEDURE: To explore leukemia characteristics of patients with CNS involvement at ALL diagnosis, we analyzed clinical features and early treatment response of 744...... leukemia and patients without such characteristics (0.50 vs. 0.61; P = 0.2). CONCLUSION: CNS involvement at diagnosis is associated with adverse prognostic features but does not indicate a less chemosensitive leukemia....

  19. Sharing of responsibilities between central and local authorities with regard to the licensing of nuclear installations

    International Nuclear Information System (INIS)

    Peltzer, P.

    1986-01-01

    With regard to sharing of responsibility in the field of nuclear licensing between central and local authorities, the Belgian State has entered into a new phase of regionalisation since the enactment of the law of August 8, 1980. This might entail a conflict of competence in case of the licensing of nuclear power plants. A general survey of foreign legislations seems to indicate that a similar risk also exists in other countries. (CW) [de

  20. Habituation of the initial responses to cold water immersion in humans: a central or peripheral mechanism?

    Science.gov (United States)

    Tipton, M J; Eglin, C M; Golden, F S

    1998-10-15

    1. The initial respiratory and cardiac responses to cold water immersion are thought to be responsible for a significant number of open water deaths each year. Previous research has demonstrated that the magnitude of these responses can be reduced by repeated immersions in cold waterwhether the site of habituation is central or peripheral. 2. Two groups of subjects undertook two 3 min head-out immersions in stirred water at 10 C of the right-hand side of the body (R). Between these two immersions (3 whole days) the control group (n = 7) were not exposed to cold water, but the habituation group (n = 8) undertook a further six 3 min head-out immersions in stirred water at 10 C of the left-hand side of the body (L). 3. Repeated L immersions reduced (P immersion a reduction (P < 0.05) in the magnitude of the responses evoked was seen in the habituation group but not in the control group, despite both groups having identical skin temperature profiles. 4. It is concluded that the mechanisms involved in producing habituation of the initial responses are located more centrally than the peripheral receptors.

  1. Networking Japan

    DEFF Research Database (Denmark)

    Hansen, Annette Skovsted

    Human Resource Development was the first and remains an important pillar in Japanese foreign aid. I will argue that Japan has access to a global network of alumni who will co-define Japanese foreign aid in the future, because Japan has encouraged alumni societies and networking since 1965. A total...... of more than a million people in more than 100 countries have attended courses in Japan funded fully or partly by Japanese ODA since the inception of the technical assistance programs in 1954 through the Colombo Plan and since 1959 through the Association of Overseas Technical Scholarships (AOTS from 2009...... HIDA). Many of these alumni have and will in the future exchange ideas and keep contact not only to Japan, but also to fellow alumni around the globe and, thereby, practice south-south exchanges, which are made possible and traceable by their established alumni network and the World Network of Friends...

  2. Central Hardwoods ecosystem vulnerability assessment and synthesis: a report from the Central Hardwoods Climate Change Response Framework project

    Science.gov (United States)

    Leslie Brandt; Hong He; Louis Iverson; Frank R. Thompson; Patricia Butler; Stephen Handler; Maria Janowiak; P. Danielle Shannon; Chris Swanston; Matthew Albrecht; Richard Blume-Weaver; Paul Deizman; John DePuy; William D. Dijak; Gary Dinkel; Songlin Fei; D. Todd Jones-Farrand; Michael Leahy; Stephen Matthews; Paul Nelson; Brad Oberle; Judi Perez; Matthew Peters; Anantha Prasad; Jeffrey E. Schneiderman; John Shuey; Adam B. Smith; Charles Studyvin; John M. Tirpak; Jeffery W. Walk; Wen J. Wang; Laura Watts; Dale Weigel; Steve. Westin

    2014-01-01

    The forests in the Central Hardwoods Region will be affected directly and indirectly by a changing climate over the next 100 years. This assessment evaluates the vulnerability of terrestrial ecosystems in the Central Hardwoods Region of Illinois, Indiana, and Missouri to a range of future climates. Information on current forest conditions, observed climate trends,...

  3. Density response to central electron heating: theoretical investigations and experimental observations in ASDEX Upgrade

    Science.gov (United States)

    Angioni, C.; Peeters, A. G.; Garbet, X.; Manini, A.; Ryter, F.; ASDEX Upgrade Team

    2004-08-01

    Theory of ion temperature gradient (ITG) and trapped electron modes (TEMs) is applied to the study of particle transport in experimental conditions with central electron heating. It is shown that in the unstable domain of TEMs, the electron thermodiffusive flux is directed outwards. By means of such a flux, a mechanism is identified likely to account for density flattening with central electron heating. Theoretical predictions are compared with experimental observations in ASDEX Upgrade. A parameter domain (including L- and H-mode plasmas) is identified, in which flattening with central electron heating is observed in the experiments. In general, this domain turns out to be the same domain in which the dominant plasma instability is a TEM. On the contrary, the dominant instability is an ITG in plasmas whose density profile is not affected significantly by central electron heating. The flattening predicted by quasi-linear theory for low density L-mode plasmas is too small compared to the experimental observations. At very high density, even when the dominant instability is an ITG, electron heating can provide density flattening, via the coupling with the ion heat channel. In these conditions the anomalous diffusivity increases in response to the increased ion heat flux, while the large collisionality makes the anomalous pinch small and the Ware pinch important.

  4. A central regulatory system largely controls transcriptional activation and repression responses to phosphate starvation in Arabidopsis.

    Directory of Open Access Journals (Sweden)

    Regla Bustos

    2010-09-01

    Full Text Available Plants respond to different stresses by inducing or repressing transcription of partially overlapping sets of genes. In Arabidopsis, the PHR1 transcription factor (TF has an important role in the control of phosphate (Pi starvation stress responses. Using transcriptomic analysis of Pi starvation in phr1, and phr1 phr1-like (phl1 mutants and in wild type plants, we show that PHR1 in conjunction with PHL1 controls most transcriptional activation and repression responses to phosphate starvation, regardless of the Pi starvation specificity of these responses. Induced genes are enriched in PHR1 binding sequences (P1BS in their promoters, whereas repressed genes do not show such enrichment, suggesting that PHR1(-like control of transcriptional repression responses is indirect. In agreement with this, transcriptomic analysis of a transgenic plant expressing PHR1 fused to the hormone ligand domain of the glucocorticoid receptor showed that PHR1 direct targets (i.e., displaying altered expression after GR:PHR1 activation by dexamethasone in the presence of cycloheximide corresponded largely to Pi starvation-induced genes that are highly enriched in P1BS. A minimal promoter containing a multimerised P1BS recapitulates Pi starvation-specific responsiveness. Likewise, mutation of P1BS in the promoter of two Pi starvation-responsive genes impaired their responsiveness to Pi starvation, but not to other stress types. Phylogenetic footprinting confirmed the importance of P1BS and PHR1 in Pi starvation responsiveness and indicated that P1BS acts in concert with other cis motifs. All together, our data show that PHR1 and PHL1 are partially redundant TF acting as central integrators of Pi starvation responses, both specific and generic. In addition, they indicate that transcriptional repression responses are an integral part of adaptive responses to stress.

  5. Central mechanisms underlying variability in the behavioral and neuroendocrine responses to stress in fish

    DEFF Research Database (Denmark)

    Moltesen, Maria Møller

    of the stress response. In mammals, the hippocampus and amygdala in the telencephalon play central roles in the process of discriminating sensory inputs that, potentially, will threaten the homeostasis of an individual. These regions are part of the limbic system, which interacts with the hypothalamic......-pituitary-adrenal axis (HPA axis). This neuroendocrine stress axis includes corticotropin-releasing factor (CRF), which regulates the release of adrenocorticotropic hormone (ACTH) from the pituitary. A peptide is released to the circulation, inducing release of glucocorticoids from the adrenal cortex....... The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) also plays an important role in the neuroendocrine stress response by controlling CRF release in hypothalamus. The transmission of 5-HT and CRF are under feedback control of glucocorticoids and interact with the stress response by affecting processes...

  6. Responsibility for reporting patient death due to hospital error in Japan when an error occurred at a referring institution.

    Science.gov (United States)

    Maeda, Shoichi; Starkey, Jay; Kamishiraki, Etsuko; Ikeda, Noriaki

    2013-12-01

    In Japan, physicians are required to report unexpected health care-associated patient deaths to the police. Patients needing to be transferred to another institution often have complex medical problems. If a medical error occurs, it may be either at the final or the referring institution. Some fear that liability will fall on the final institution regardless of where the error occurred or that the referring facility may oppose such reporting, leading to a failure to report to police or to recommend an autopsy. Little is known about the actual opinions of physicians and risk managers in this regard. The authors sent standardised, self-administered questionnaires to all hospitals in Japan that participate in the national general residency program. Most physicians and risk managers in Japan indicated that they would report a patient's death to the police where the patient has been transferred. Of those who indicated they would not report to the police, the majority still indicated they would recommend an autopsy

  7. Stressor specificity of central neuroendocrine responses: implications for stress-related disorders.

    Science.gov (United States)

    Pacák, K; Palkovits, M

    2001-08-01

    Despite the fact that many research articles have been written about stress and stress-related diseases, no scientifically accepted definition of stress exists. Selye introduced and popularized stress as a medical and scientific idea. He did not deny the existence of stressor-specific response patterns; however, he emphasized that such responses did not constitute stress, only the shared nonspecific component. In this review we focus mainly on the similarities and differences between the neuroendocrine responses (especially the sympathoadrenal and the sympathoneuronal systems and the hypothalamo-pituitary-adrenocortical axis) among various stressors and a strategy for testing Selye's doctrine of nonspecificity. In our experiments, we used five different stressors: immobilization, hemorrhage, cold exposure, pain, or hypoglycemia. With the exception of immobilization stress, these stressors also differed in their intensities. Our results showed marked heterogeneity of neuroendocrine responses to various stressors and that each stressor has a neurochemical "signature." By examining changes of Fos immunoreactivity in various brain regions upon exposure to different stressors, we also attempted to map central stressor-specific neuroendocrine pathways. We believe the existence of stressor-specific pathways and circuits is a clear step forward in the study of the pathogenesis of stress-related disorders and their proper treatment. Finally, we define stress as a state of threatened homeostasis (physical or perceived treat to homeostasis). During stress, an adaptive compensatory specific response of the organism is activated to sustain homeostasis. The adaptive response reflects the activation of specific central circuits and is genetically and constitutionally programmed and constantly modulated by environmental factors.

  8. Preparing for creative responses to “beyond assumed level” disasters: lessons from the ICT management in the 2011 Great East Japan earthquake crisis

    Directory of Open Access Journals (Sweden)

    Mihoko Sakurai

    2012-12-01

    Full Text Available A survey of the municipal government ICT divisions during and after the 2011 Great East Japan Earthquake and Tsunami crisis reveals the need for creative responses for “beyond assumed level” disasters. Complexity and diversity of the damage were simply too great for any plans to assume. Resident needs toward the municipal governments were also diverse and changed quickly as the time went by. The research also indicates that there would be ways to strengthen the capabilities to execute such spontaneous responses. Creative solutions executed during the 3.11 crisis were supported by the existence of open source software available on the net and skilled engineers that were capable of exploiting them. Frugal information system will be useful to improve preparedness for creative responses

  9. Immune and Inflammatory Responses in the Central Nervous System: Modulation by Astrocytes

    DEFF Research Database (Denmark)

    Penkowa, Milena; hidalgo, juan; aschner, michael

    2008-01-01

    Beyond their long-recognized support functions, astrocytes are active partners of neurons in processing information, synaptic integration, and production of trophic factors, just to name a few. Both microglia and astrocytes produce and secrete a number of cytokines, modulating and integrating...... the communication between hematogenous cells and resident cells of the central nervous system (CNS). This review will address (1) the functions of astrocytes in the normal brain and (2) their role in surveying noxious stimuli within the brain, with particular emphasis on astrocytic responses to damage or disease...

  10. Acoustic profiling and surface imaging of the coastal area near the subduction zone: the eastern coastal area of Boso Peninsula, Central Japan.

    Science.gov (United States)

    Furuyama, S.; Sato, T.

    2016-12-01

    The plate motion of the Philippine Sea plate and the Pacific plate influences geology of coastal area in the Pacific side in Japan and sometime causes extensive damage of human activity, such as the Great East Japan Earthquake. It is important to understand the geological structures in a coastal area for disaster prevention. Especially, rapid equipment of geoinformations is highly demanded in the Kanto region where covers capital Tokyo area. Geological Survey of Japan investigated the eastern coastal area in Boso Peninsula, eastern part of the Kanto region, Japan within two years from 2014 to 2015. We obtained seismic sections of ca. 1100 km in total length with a boomer and multi-channel streamer (24 channel with 3.125 m spacing) and report the geological significance of the subsurface structures. The survey area is divided into the northern part of Kujukuri area, the southern part of Kujukuri area, the coastal part of Kujukuri area based on topography and geological structures. In these Kujukuri areas, two strata that show distinct stratification bounded by distinct unconformity distribute and we define them as the Kujukuri A Unit and the Kujukuri B Unit, in ascending order. The lower sequence has some folds and normal faults. These folds that deformed the Kujukuri B Unit extend toward north-northeast in the northern part of Kujukuri area. They contributed to development of wide shelf distributed in this area. In the southern part of Kujukuri area, a lot of faults deformed the Kujukuri B Unit and some of them displaced the Kujukuri A Unit over 10 msec (two way travel). Normal faults developed in the Kujukuri B Unit over 10 msec made grabens and half grabens in the coastal part of Kujukuri area and these grabens and half grabens could make the lowland in the Kujukuri coastal area. The combination of these geological structures identified in the Kujukuri areas could reflect the transition of stress field associated with the subduction of the Philippine Sea plate

  11. Central and peripheral mechanisms underlying gastric distention inhibitory reflex responses in hypercapnic-acidotic rats.

    Science.gov (United States)

    Tjen-A-Looi, Stephanie C; Hsiao, An-Fu; Longhurst, John C

    2011-03-01

    We have observed that in chloralose-anesthetized animals, gastric distension (GD) typically increases blood pressure (BP) under normoxic normocapnic conditions. However, we recently noted repeatable decreases in BP and heart rate (HR) in hypercapnic-acidotic rats in response to GD. The neural pathways, central processing, and autonomic effector mechanisms involved in this cardiovascular reflex response are unknown. We hypothesized that GD-induced decrease in BP and HR reflex responses are mediated during both withdrawal of sympathetic tone and increased parasympathetic activity, involving the rostral (rVLM) and caudal ventrolateral medulla (cVLM) and the nucleus ambiguus (NA). Rats anesthetized with ketamine and xylazine or α-chloralose were ventilated and monitored for HR and BP changes. The extent of cardiovascular inhibition was related to the extent of hypercapnia and acidosis. Repeated GD with both anesthetics induced consistent falls in BP and HR. The hemodynamic inhibitory response was reduced after blockade of the celiac ganglia or the intraabdominal vagal nerves with lidocaine, suggesting that the decreased BP and HR responses were mediated by both sympathetic and parasympathetic afferents. Blockade of the NA decreased the bradycardia response. Microinjection of kainic acid into the cVLM reduced the inhibitory BP response, whereas depolarization blockade of the rVLM decreased both BP and HR inhibitory responses. Blockade of GABA(A) receptors in the rVLM also reduced the BP and HR reflex responses. Atropine methyl bromide completely blocked the reflex bradycardia, and atenolol blocked the negative chronotropic response. Finally, α(1)-adrenergic blockade with prazosin reversed the depressor. Thus, in the setting of hypercapnic-acidosis, a sympathoinhibitory cardiovascular response is mediated, in part, by splanchnic nerves and is processed through the rVLM and cVLM. Additionally, a vagal excitatory reflex, which involves the NA, facilitates the GD

  12. Safety and effectiveness of tacrolimus add-on therapy for rheumatoid arthritis patients without an adequate response to biological disease-modifying anti-rheumatic drugs (DMARDs): Post-marketing surveillance in Japan.

    Science.gov (United States)

    Takeuchi, Tsutomu; Ishida, Kota; Shiraki, Katsuhisa; Yoshiyasu, Takashi

    2018-01-01

    Post-marketing surveillance (PMS) was conducted to assess the safety and effectiveness of tacrolimus (TAC) add-on therapy for patients with rheumatoid arthritis (RA) and an inadequate response to biological disease-modifying anti-rheumatic drugs (DMARDs). Patients with RA from 180 medical sites across Japan were registered centrally with an electronic investigation system. The observational period was 24 weeks from the first day of TAC administration concomitantly with biological DMARDs. Safety and effectiveness populations included 624 and 566 patients, respectively. Patients were predominantly female (81.1%), with a mean age of 61.9 years. Overall, 125 adverse drug reactions (ADRs) occurred in 94 patients (15.1%), and 15 serious ADRs occurred in 11 patients (1.8%). These incidences were lower compared with previously reported incidences after TAC treatment in PMS, and all of the observed ADRs were already known. A statistically significant improvement was observed in the primary effectiveness variable of Simplified Disease Activity Index after TAC treatment; 62.7% of patients achieved remission or low disease activity at week 24. TAC is well tolerated and effective when used as an add-on to biological DMARDs in Japanese patients with RA who do not achieve an adequate response to biological DMARDs in a real-world clinical setting.

  13. Factors affecting the United Nations' response to natural disasters: what determines the allocation of the Central Emergency Response Fund?

    Science.gov (United States)

    Robinson, Tyler D; Oliveira, Thiago M; Kayden, Stephanie

    2017-10-01

    Natural disasters can overwhelm the domestic response of a country, leaving it dependent on external humanitarian relief. The Central Emergency Response Fund (CERF) of the United Nations centralises humanitarian funding and thus allows for a rapid response. This study combined data to analyse the factors that affected the allocation of CERF funding to countries that suffered a natural disaster between 2007 and 2013. It generated descriptive statistics and information on relative risks, and performed regressions of CERF funding across countries. There were 4,346 disasters in total in 188 countries between 2007 and 2013. CERF provided USD 2.98 billion to 87 countries, comprising 3.3 per cent of their total humanitarian funding. CERF more frequently supplied aid to countries in North Africa and the Middle East, and to those that had suffered geophysical disasters. Appropriately, it funds vulnerable countries experiencing severe natural disasters, yet its funding may be affected by variables beyond severity and vulnerability. Further investigation is warranted, therefore. © 2017 The Author(s). Disasters © Overseas Development Institute, 2017.

  14. Morphologic characteristics of central pulmonary thromboemboli predict haemodynamic response in massive pulmonary embolism.

    Science.gov (United States)

    Podbregar, Matej; Voga, Gorazd; Krivec, Bojan

    2004-08-01

    On hospital admission, the morphology of the central pulmonary artery thromboemboli is an independent predictor of 30-day mortality in patients with massive pulmonary embolism (MPE). This may be due to the differential susceptibility of thromboemboli to thrombolysis. The aim of this study was to assess haemodynamic response to treatment in patients with MPE and morphologically different thromboemboli. Prospective observational study. An 11-bed closed medical ICU at a 860-bed community general hospital. Twelve consecutive patients with shock or hypotension due to MPE and central pulmonary thromboemboli detected by transesophageal echocardiography who were treated with thrombolysis between January 2000 through April 2002. Patients were divided into two groups according to the characteristics of detected central pulmonary thromboemboli: group 1, thrombi with one or more long, mobile parts; and group 2, immobile thrombi. Urokinase infusion was terminated when mixed venous oxygen saturation was stabilized above 60% for 15 min. At 2 h, the total pulmonary vascular resistance index was reduced more in group 1 than group 2 [from 27+/-12 mmHg/(l.min.m(2)) to 14+/-6 mmHg/(l.min.m(2)) (-52%) vs 27+/-8 mmHg/(l.min.m(2)) to 23+/-10 mmHg/(l.min.m(2)) (-15%), respectively, P=0.04]. In group 1 thrombolysis was terminated earlier than group 2 (89+/-40 min vs 210+/-62 min, respectively, P= 0.0024). The cumulative dose of urokinase used in group 1 was lower than group 2 (1.7+/-0.3 M i.u. vs 2.7+/-0.5 M i.u., respectively, P= 0.023). Haemodynamic stabilization is achieved faster in patients with mobile central thromboemboli detected by transesophageal echocardiography during MPE.

  15. Estradiol modulates the anorexic response to central glucagon-like peptide 1.

    Science.gov (United States)

    Maske, Calyn B; Jackson, Christine M; Terrill, Sarah J; Eckel, Lisa A; Williams, Diana L

    2017-07-01

    Estrogens suppress feeding in part by enhancing the response to satiation signals. Glucagon-like peptide 1 (GLP-1) acts on receptor populations both peripherally and centrally to affect food intake. We hypothesized that modulation of the central GLP-1 system is one of the mechanisms underlying the effects of estrogens on feeding. We assessed the anorexic effect of 0, 1, and 10μg doses of GLP-1 administered into the lateral ventricle of bilaterally ovariectomized (OVX) female rats on a cyclic regimen of either 2μg β-estradiol-3-benzoate (EB) or oil vehicle 30min prior to dark onset on the day following hormone treatment. Central GLP-1 treatment significantly suppressed food intake in EB-treated rats at both doses compared to vehicle, whereas only the 10μg GLP-1 dose was effective in oil-treated rats. To follow up, we examined whether physiologic-dose cyclic estradiol treatment influences GLP-1-induced c-Fos in feeding-relevant brain areas of OVX females. GLP-1 significantly increased c-Fos expression in the area postrema (AP) and nucleus of the solitary tract (NTS), and the presence of estrogens may be required for this effect in the paraventricular nucleus of the hypothalamus (PVN). Together, these data suggest that modulation of the central GLP-1 system may be one of the mechanisms by which estrogens suppress food intake, and highlight the PVN as a region of interest for future investigation. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Thermal Responses of Growth and Toxin Production in Four Prorocentrum Species from the Central Red Sea

    KAUST Repository

    Aynousah, Arwa

    2017-06-01

    Harmful algae studies, in particular toxic dinoflagellates, and their response to global warming in the Red Sea are still limited. This study was aimed to be the first to characterize the identity, thermal responses and toxin production of four Prorocentrum strains isolated from the Central Red Sea, Saudi Arabia. Morphological and molecular phylogenetic analysis identified the strains as P. elegans, P. rhathymum and P. emarginatum. However, the identity of strain P. sp.6 is currently unresolved, albeit sharing close affinity with P. leve. Growth experiments showed that all species could grow at 24-32°C, but only P. sp.6 survived the 34°C treatment. The optimum temperatures (Topt) estimated from the Gaussian model corresponded to 27.17, 29.33, 26.87, and 27.64°C for P. sp.6, P. elegans, P. rhathymum and P. emarginatum, respectively. However, some discrepancy with the Topt derived from the growth performance were observed for P. elegans and P. emarginatum, as thermal responses differed from the typical Gaussian fit. The Prorocentrum species examined showed a sharp decrease after the optimum temperature resulting in very high activation energies for the fall slope, especially for P. elegans and P. emarginatum. The minimum critical temperature limit for growth was not detected within the range of temperatures examined. Subsequently, high performance liquid chromatography coupled with mass spectrometry (HPLC-MS) analysis revealed all species as non okadaic acid (OA, common toxin of the Prorocentrum genus) producers at any temperature treatment. However, other forms of toxin (i.e. fast acting toxins) not examined here could be produced. Therefore, further investigations are required. The results of this study provided significant contribution to our knowledge regarding the presence, thermal response and toxin production of four Prorocentrum species from the Central Red Sea, Saudi Arabia.

  17. Widespread seismicity excitation throughout central Japan following the 2011 M=9.0 Tohoku earthquake and its interpretation by Coulomb stress transfer

    Science.gov (United States)

    Toda, S.; Stein, R.S.; Lin, J.

    2011-01-01

    We report on a broad and unprecedented increase in seismicity rate following the M=9.0 Tohoku mainshock for M ≥ 2 earthquakes over inland Japan, parts of the Japan Sea and Izu islands, at distances of up to 425 km from the locus of high (≥15 m) seismic slip on the megathrust. Such an increase was not seen for the 2004 M=9.1 Sumatra or 2010 M=8.8 Chile earthquakes, but they lacked the seismic networks necessary to detect such small events. Here we explore the possibility that the rate changes are the product of static Coulomb stress transfer to small faults. We use the nodal planes of M ≥ 3.5 earthquakes as proxies for such small active faults, and find that of fifteen regions averaging ~80 by 80 km in size, 11 show a positive association between calculated stress changes and the observed seismicity rate change, 3 show a negative correlation, and for one the changes are too small to assess. This work demonstrates that seismicity can turn on in the nominal stress shadow of a mainshock as long as small geometrically diverse active faults exist there, which is likely quite common.

  18. Japan 2014

    DEFF Research Database (Denmark)

    Selmer, Finn

    2014-01-01

    In March 2014 a group of teachers and students from the Royal Danish Academy of Fine Arts Schools of Architecture, Design and Conservation, School of Architecture, Study Dept. 3 went on a study trip to Japan. This publication collects observations and reflections that the participants of the trip...

  19. Improved nuclear emergency management system reflecting lessons learned from the emergency response at Fukushima Daini Nuclear Power Station after the Great East Japan Earthquake

    International Nuclear Information System (INIS)

    Kawamura, Shinichi; Narabayashi, Tadashi

    2016-01-01

    Three nuclear reactors at Fukushima Daini Nuclear Power Station lost all their ultimate heat sinks owing to damage from the tsunami caused by the Great East Japan Earthquake on March 11, 2011. Water was injected into the reactors by alternate measures, damaged cooling systems were restored with promptly supplied substitute materials, and all the reactors were brought to a cold shutdown state within four days. Lessons learned from this experience were identified to improve emergency management, especially in the areas of strategic response planning, logistics, and functions supporting response activities continuing over a long period. It was found that continuous planning activities reflecting information from plant parameters and response action results were important, and that relevant functions in emergency response organizations should be integrated. Logistics were handled successfully but many difficulties were experienced. Therefore, their functions should be clearly established and improved by emergency response organizations. Supporting emergency responders in the aspects of their physical and mental conditions was important for sustaining continuous response. As a platform for improvement, the concept of the Incident Command System was applied for the first time to a nuclear emergency management system, with specific improvement ideas such as a phased approach in response planning and common operation pictures. (author)

  20. The central role of hypothalamic inflammation in the acute illness response and cachexia.

    Science.gov (United States)

    Burfeind, Kevin G; Michaelis, Katherine A; Marks, Daniel L

    2016-06-01

    When challenged with a variety of inflammatory threats, multiple systems across the body undergo physiological responses to promote defense and survival. The constellation of fever, anorexia, and fatigue is known as the acute illness response, and represents an adaptive behavioral and physiological reaction to stimuli such as infection. On the other end of the spectrum, cachexia is a deadly and clinically challenging syndrome involving anorexia, fatigue, and muscle wasting. Both of these processes are governed by inflammatory mediators including cytokines, chemokines, and immune cells. Though the effects of cachexia can be partially explained by direct effects of disease processes on wasting tissues, a growing body of evidence shows the central nervous system (CNS) also plays an essential mechanistic role in cachexia. In the context of inflammatory stress, the hypothalamus integrates signals from peripheral systems, which it translates into neuroendocrine perturbations, altered neuronal signaling, and global metabolic derangements. Therefore, we will discuss how hypothalamic inflammation is an essential driver of both the acute illness response and cachexia, and why this organ is uniquely equipped to generate and maintain chronic inflammation. First, we will focus on the role of the hypothalamus in acute responses to dietary and infectious stimuli. Next, we will discuss the role of cytokines in driving homeostatic disequilibrium, resulting in muscle wasting, anorexia, and weight loss. Finally, we will address mechanisms and mediators of chronic hypothalamic inflammation, including endothelial cells, chemokines, and peripheral leukocytes. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Central pathology review with two-stage quality assurance for pathological response after neoadjuvant chemotherapy in the ARTemis Trial.

    Science.gov (United States)

    Thomas, Jeremy St John; Provenzano, Elena; Hiller, Louise; Dunn, Janet; Blenkinsop, Clare; Grybowicz, Louise; Vallier, Anne-Laure; Gounaris, Ioannis; Abraham, Jean; Hughes-Davies, Luke; McAdam, Karen; Chan, Stephen; Ahmad, Rizvana; Hickish, Tamas; Houston, Stephen; Rea, Daniel; Caldas, Carlos; Bartlett, John Ms; Cameron, David Allan; Hayward, Richard Laurence; Earl, Helena Margaret

    2017-08-01

    The ARTemis Trial tested standard neoadjuvant chemotherapy±bevacizumab in the treatment of HER2-negative early breast cancer. We compare data from central pathology review with report review and also the reporting behavior of the two central pathologists. Eight hundred women with HER2-negative early invasive breast cancer were recruited. Response to chemotherapy was assessed from local pathology reports for pathological complete response in breast and axillary lymph nodes. Sections from the original core biopsy and surgical excision were centrally reviewed by one of two trial pathologists blinded to the local pathology reports. Pathologists recorded response to chemotherapy descriptively and also calculated residual cancer burden. 10% of cases were double-reported to compare the central pathologists' reporting behavior. Full sample retrieval was obtained for 681 of the 781 patients (87%) who underwent surgery within the trial and were evaluable for pathological complete response. Four hundred and eighty-three (71%) were assessed by JSJT, and 198 (29%) were assessed by EP. Residual cancer burden calculations were possible in 587/681 (86%) of the centrally reviewed patients, as 94/681 (14%) had positive sentinel nodes removed before neoadjuvant chemotherapy invalidating residual cancer burden scoring. Good concordance was found between the two pathologists for residual cancer burden classes within the 65-patient quality assurance exercise (kappa 0.63 (95% CI: 0.57-0.69)). Similar results were obtained for the between-treatment arm comparison both from the report review and the central pathology review. For pathological complete response, report review was as good as central pathology review but for minimal residual disease, report review overestimated the extent of residual disease. In the ARTemis Trial central pathology review added little in the determination of pathological complete response but had a role in evaluating low levels of residual disease. Calculation

  2. Blockade of central vasopressin receptors reduces the cardiovascular response to acute stress in freely moving rats.

    Science.gov (United States)

    Stojicić, S; Milutinović-Smiljanić, S; Sarenac, O; Milosavljević, S; Paton, J F R; Murphy, D; Japundzić-Zigon, N

    2008-04-01

    To investigate the contribution of central vasopressin receptors to blood pressure (BP) and heart rate (HR) response to stress we injected non-peptide selective V(1a) (SR49059), V(1b) (SSR149415), V(2) (SR121463) receptor antagonists, diazepam or vehicle in the lateral cerebral ventricle of conscious freely moving rats stressed by blowing air on their heads for 2 min. Cardiovascular effects of stress were evaluated by analyzing maximum increase of BP and HR (MAX), latency of maximum response (LAT), integral under BP and HR curve (integral), duration of their recovery and spectral parameters of BP and HR indicative of increased sympathetic outflow (LF(BP) and LF/HF(HR)). Moreover, the increase of serum corticosterone was measured. Exposure to air-jet stress induced simultaneous increase in BP and HR followed by gradual decline during recovery while LF(BP) oscillation remained increased as well as serum corticosterone level. Rats pre-treated with vasopressin receptor antagonists were not sedated while diazepam induced sedation that persisted during exposure to stress. V(1a), V(1b) and V(2) receptor antagonists applied separately did not modify basal values of cardiovascular parameters but prevented the increase in integral(BP). In addition, V(1b) and V(2) receptor antagonists reduced BP(MAX) whereas V(1a), V(1b) antagonist and diazepam reduced HR(MAX) induced by exposure to air-jet stress. All drugs shortened the recovery period, prevented the increase of LF(BP) without affecting the increase in serum corticosterone levels. Results indicate that vasopressin receptors located within the central nervous system mediate, in part, the cardiovascular response to air-jet stress without affecting either the neuroendocrine component or inducing sedation. They support the view that the V(1b) receptor antagonist may be of potential therapeutic value in reducing arterial pressure induced by stress-related disorders.

  3. Neuropeptides in the posterodorsal medial amygdala modulate central cardiovascular reflex responses in awake male rats

    Energy Technology Data Exchange (ETDEWEB)

    Quagliotto, E. [Departamento de Ciências Básicas da Saúde/Fisiologia, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS (Brazil); Programa de Pós-Graduação em Neurociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS (Brazil); Casali, K.R. [Instituto de Ciência e Tecnologia, Universidade Federal de São Paulo, São José dos Campos, SP (Brazil); Dal Lago, P. [Departamento de Fisioterapia, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS (Brazil); Rasia-Filho, A.A. [Departamento de Ciências Básicas da Saúde/Fisiologia, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS (Brazil); Programa de Pós-Graduação em Neurociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS (Brazil)

    2014-11-21

    The rat posterodorsal medial amygdala (MePD) links emotionally charged sensory stimuli to social behavior, and is part of the supramedullary control of the cardiovascular system. We studied the effects of microinjections of neuroactive peptides markedly found in the MePD, namely oxytocin (OT, 10 ng and 25 pg; n=6/group), somatostatin (SST, 1 and 0.05 μM; n=8 and 5, respectively), and angiotensin II (Ang II, 50 pmol and 50 fmol; n=7/group), on basal cardiovascular activity and on baroreflex- and chemoreflex-mediated responses in awake adult male rats. Power spectral and symbolic analyses were applied to pulse interval and systolic arterial pressure series to identify centrally mediated sympathetic/parasympathetic components in the heart rate variability (HRV) and arterial pressure variability (APV). No microinjected substance affected basal parameters. On the other hand, compared with the control data (saline, 0.3 µL; n=7), OT (10 ng) decreased mean AP (MAP{sub 50}) after baroreflex stimulation and increased both the mean AP response after chemoreflex activation and the high-frequency component of the HRV. OT (25 pg) increased overall HRV but did not affect any parameter of the symbolic analysis. SST (1 μM) decreased MAP{sub 50}, and SST (0.05 μM) enhanced the sympathovagal cardiac index. Both doses of SST increased HRV and its low-frequency component. Ang II (50 pmol) increased HRV and reduced the two unlike variations pattern of the symbolic analysis (P<0.05 in all cases). These results demonstrate neuropeptidergic actions in the MePD for both the increase in the range of the cardiovascular reflex responses and the involvement of the central sympathetic and parasympathetic systems on HRV and APV.

  4. Neuropeptides in the posterodorsal medial amygdala modulate central cardiovascular reflex responses in awake male rats

    International Nuclear Information System (INIS)

    Quagliotto, E.; Casali, K.R.; Dal Lago, P.; Rasia-Filho, A.A.

    2014-01-01

    The rat posterodorsal medial amygdala (MePD) links emotionally charged sensory stimuli to social behavior, and is part of the supramedullary control of the cardiovascular system. We studied the effects of microinjections of neuroactive peptides markedly found in the MePD, namely oxytocin (OT, 10 ng and 25 pg; n=6/group), somatostatin (SST, 1 and 0.05 μM; n=8 and 5, respectively), and angiotensin II (Ang II, 50 pmol and 50 fmol; n=7/group), on basal cardiovascular activity and on baroreflex- and chemoreflex-mediated responses in awake adult male rats. Power spectral and symbolic analyses were applied to pulse interval and systolic arterial pressure series to identify centrally mediated sympathetic/parasympathetic components in the heart rate variability (HRV) and arterial pressure variability (APV). No microinjected substance affected basal parameters. On the other hand, compared with the control data (saline, 0.3 µL; n=7), OT (10 ng) decreased mean AP (MAP 50 ) after baroreflex stimulation and increased both the mean AP response after chemoreflex activation and the high-frequency component of the HRV. OT (25 pg) increased overall HRV but did not affect any parameter of the symbolic analysis. SST (1 μM) decreased MAP 50 , and SST (0.05 μM) enhanced the sympathovagal cardiac index. Both doses of SST increased HRV and its low-frequency component. Ang II (50 pmol) increased HRV and reduced the two unlike variations pattern of the symbolic analysis (P<0.05 in all cases). These results demonstrate neuropeptidergic actions in the MePD for both the increase in the range of the cardiovascular reflex responses and the involvement of the central sympathetic and parasympathetic systems on HRV and APV

  5. Spent fuel management in Japan

    International Nuclear Information System (INIS)

    Shirahashi, K.; Maeda, M.; Nakai, T.

    1996-01-01

    Japan has scarce energy resources and depends on foreign resources for 84% of its energy needs. Therefore, Japan has made efforts to utilize nuclear power as a key energy source since mid-1950's. Today, the nuclear energy produced from 49 nuclear power plants is responsible for about 31% of Japan's total electricity supply. The cumulative amount of spent fuel generated as of March 1995 was about 11,600 Mg U. Japan's policy of spent fuel management is to reprocess spent nuclear fuel and recycle recovered plutonium and uranium as nuclear fuel. The Tokai reprocessing plant continues stable operation keeping the annual treatment capacity or around 90 Mg U. A commercial reprocessing plant is under construction at Rokkasho, northern part of Japan. Although FBR is the principal reactor to use plutonium, LWR will be a major power source for some time and recycling of the fuel in LWRs will be prompted. (author). 3 figs

  6. Psychophysical and cerebral responses to heat stimulation in patients with central pain, painless central sensory loss, and in healthy persons.

    Science.gov (United States)

    Casey, Kenneth L; Geisser, Michael; Lorenz, Jürgen; Morrow, Thomas J; Paulson, Pamela; Minoshima, Satoshi

    2012-02-01

    Patients with central pain (CP) typically have chronic pain within an area of reduced pain and temperature sensation, suggesting an impairment of endogenous pain modulation mechanisms. We tested the hypothesis that some brain structures normally activated by cutaneous heat stimulation would be hyperresponsive among patients with CP but not among patients with a central nervous system lesion causing a loss of heat or nociceptive sensation with no pain (NP). We used H(2)(15)O positron emission tomography to measure, in 15 healthy control participants, 10 NP patients, and 10 CP patients, increases in regional cerebral blood flow among volumes of interest (VOI) from the resting (no stimulus) condition during bilateral contact heat stimulation at heat detection, heat pain threshold, and heat pain tolerance levels. Both patient groups had a reduced perception of heat intensity and unpleasantness on the clinically affected side and a bilateral impairment of heat detection. Compared with the HC group, both NP and CP patients had more hyperactive and hypoactive VOI in the resting state and more hyperresponsive and hyporesponsive VOI during heat stimulation. Compared with NP patients, CP patients had more hyperresponsive VOI in the intralaminar thalamus and sensory-motor cortex during heat stimulation. Our results show that focal CNS lesions produce bilateral sensory deficits and widespread changes in the nociceptive excitability of the brain. The increased nociceptive excitability within the intralaminar thalamus and sensory-motor cortex of our sample of CP patients suggests an underlying pathophysiology for the pain in some central pain syndromes. Published by Elsevier B.V.

  7. Responses of two tall buildings in Tokyo, Japan, before, during, and after the M9.0 Tohoku earthquake of 11 March 2011

    Science.gov (United States)

    Çelebi, Mehmet; Hisada, Yoshiuaki; Omrani, Roshanak; Ghahari, S. Farid; Taciroglu, Ertugrul

    2016-01-01

    The 11 March 2011 M 9.0 Tohoku earthquake generated significant long duration shaking that propagated hundreds of kilometers from the epicenter and affected urban areas throughout much of Honshu. Recorded responses of tall buildings at several hundred km from the epicenter of the main shock and other events show tall buildings were affected by long-period motions of events at distant sources. This study presents behavioral aspects of 29-story and 30-story neighboring buildings in the Shinjuku area of Tokyo, Japan, as inferred from records retrieved from a sparse array of accelerometers deployed in the superstructures, at ground and 100 m below the ground level over a time interval covering before, during, and after the main shock. Such long-period effects are common in several regions of Japan as well as in the United States and in other seismically active countries. Permanent shifts in fundamental frequencies are observed. Drift ratios indicate possible structural nonlinear behavior occurred during the main shock. The need to consider risks to built environments from distant sources, including those in neighboring countries, is emphasized.

  8. Economic potential of demand response at household level—Are Central-European market conditions sufficient?

    International Nuclear Information System (INIS)

    Prüggler, Natalie

    2013-01-01

    The aim of this paper is to show the economic potential of demand response (DR) on household level at Central European market conditions. Thereby, required economic benefits for consumers' participation, the realistic load shifting potential at household level and the estimation of essential intelligent infrastructure costs are discussed. The core of this paper builds a case-study applying spot market-oriented load shifting from the supplier's point of view by using Austrian electricity market data, household load profiles as well as a heat pump and e-car charging load profile. It is demonstrated which cost savings for suppliers can be derived from such load shifting procedure at household level. Furthermore, upper cost limits for intelligent infrastructure in order to break-even are derived. Results suggest to take a critical look at European discussions on DR implementation on household level, showing that at Central European market conditions the potential for DR at household level is restricted to significant loads and hence, the applied load shifting strategy is only beneficial with application to heat pumps. In contrast, the frequently discussed shifting of conventional household devices' loads (such as washing machines) economically does not add up. - Highlights: • Calculation of economic potential of domestic DR at Central European market conditions. • Model and case-study of spot market-oriented load shifting from supplier's perspective. • Derivation of supplier's cost savings and upper cost limits for ICT infrastructure. • Results show economic potential of domestic DR to be restricted to significant loads. • Shifting of washing machines economically does not pay off in contrast to heat pumps

  9. Postfire responses of the woody flora of Central Chile: Insights from a germination experiment.

    Science.gov (United States)

    Gómez-González, Susana; Paula, Susana; Cavieres, Lohengrin A; Pausas, Juli G

    2017-01-01

    Fire is a selective agent shaping plant traits and community assembly in fire-prone ecosystems. However, in ecosystems with no fire history, it can be a cause of land degradation when it is suddenly introduced by humans, as plant species may not be able to respond to such novel disturbance. Unlike other Mediterranean-type ecosystems (MTE) of the world, natural fires have not been frequent during the Quaternary in the matorral of Central Chile, and thus, plant adaptive responses are expected to be uncommon. We evaluated the effect of heat shock on seed survival and germination of 21 native woody plants of the Chilean matorral and compiled information on smoke-stimulation and resprouting, to evaluate the importance of fire-adaptive responses in the context of the other MTE. We found that in the Chilean woody flora negative seed responses to fire cues were more frequent than positive responses. Although resprouting is a relatively widespread trait, fire-stimulated germination is not as common in the Chilean matorral as in other MTE. The seeds of seven endemic species were strongly damaged by fire cues and this should be considered in post-fire restoration planning. However, our results also showed that many species were resistant to elevated doses of heat shock and in some, germination was even stimulated. Thus, future research should focus on the evolutionary causes of these responses. These findings could help to develop strategies for fire management in the Chilean matorral. In addition, they will improve our understanding of the evolutionary forces that shaped this plant community and to better frame this region among the other MTE worldwide.

  10. Postfire responses of the woody flora of Central Chile: Insights from a germination experiment.

    Directory of Open Access Journals (Sweden)

    Susana Gómez-González

    Full Text Available Fire is a selective agent shaping plant traits and community assembly in fire-prone ecosystems. However, in ecosystems with no fire history, it can be a cause of land degradation when it is suddenly introduced by humans, as plant species may not be able to respond to such novel disturbance. Unlike other Mediterranean-type ecosystems (MTE of the world, natural fires have not been frequent during the Quaternary in the matorral of Central Chile, and thus, plant adaptive responses are expected to be uncommon. We evaluated the effect of heat shock on seed survival and germination of 21 native woody plants of the Chilean matorral and compiled information on smoke-stimulation and resprouting, to evaluate the importance of fire-adaptive responses in the context of the other MTE. We found that in the Chilean woody flora negative seed responses to fire cues were more frequent than positive responses. Although resprouting is a relatively widespread trait, fire-stimulated germination is not as common in the Chilean matorral as in other MTE. The seeds of seven endemic species were strongly damaged by fire cues and this should be considered in post-fire restoration planning. However, our results also showed that many species were resistant to elevated doses of heat shock and in some, germination was even stimulated. Thus, future research should focus on the evolutionary causes of these responses. These findings could help to develop strategies for fire management in the Chilean matorral. In addition, they will improve our understanding of the evolutionary forces that shaped this plant community and to better frame this region among the other MTE worldwide.

  11. The relation of somatotypes and stress response to central serous chorioretinopathy.

    Science.gov (United States)

    Schwartz, Roy; Rozenberg, Assaf; Loewenstein, Anat; Goldstein, Michaella

    2017-12-01

    To investigate a possible relationship between central serous chorioretinopathy (CSC) and specific body types and compositions (somatotypes), and to examine the cortisol stress response among CSC patients of different somatotypes in comparison with healthy subjects. Prospective case-control study. A group of 28 patients with a previous or current diagnosis of CSC was compared with a group of 26 healthy subjects. Anthropometric measurements were used to estimate somatotype ratings in all subjects. Serum cortisol was measured at rest and following a stress-inducing computerized test in order to estimate response to stress in both groups. The main outcome measures included somatotype categorization and the change in serum cortisol following stress in both groups. No significant difference in somatotype composition was found between the groups. There was no statistically significant difference between the groups in the elevation of cortisol following the stress-inducing test. The sample size was too small to exclude or find any significant difference between the different 13 subgroups of somatotype composition in the elevation of cortisol. Our study did not show a typical somatotype related to CSC. While previous studies showed higher cortisol values in CSC patients, we did not see a higher elevation in blood cortisol following a stress response in this group in comparison with healthy subjects.

  12. Peripheral, central and behavioral responses to the cuticular pheromone bouquet in Drosophila melanogaster males.

    Directory of Open Access Journals (Sweden)

    Tsuyoshi Inoshita

    Full Text Available Pheromonal communication is crucial with regard to mate choice in many animals including insects. Drosophila melanogaster flies produce a pheromonal bouquet with many cuticular hydrocarbons some of which diverge between the sexes and differently affect male courtship behavior. Cuticular pheromones have a relatively high weight and are thought to be -- mostly but not only -- detected by gustatory contact. However, the response of the peripheral and central gustatory systems to these substances remains poorly explored. We measured the effect induced by pheromonal cuticular mixtures on (i the electrophysiological response of peripheral gustatory receptor neurons, (ii the calcium variation in brain centers receiving these gustatory inputs and (iii the behavioral reaction induced in control males and in mutant desat1 males, which show abnormal pheromone production and perception. While male and female pheromones induced inhibitory-like effects on taste receptor neurons, the contact of male pheromones on male fore-tarsi elicits a long-lasting response of higher intensity in the dedicated gustatory brain center. We found that the behavior of control males was more strongly inhibited by male pheromones than by female pheromones, but this difference disappeared in anosmic males. Mutant desat1 males showed an increased sensitivity of their peripheral gustatory neurons to contact pheromones and a behavioral incapacity to discriminate sex pheromones. Together our data indicate that cuticular hydrocarbons induce long-lasting inhibitory effects on the relevant taste pathway which may interact with the olfactory pathway to modulate pheromonal perception.

  13. Subtropical Low Cloud Responses to Central and Eastern Pacific El Nino Events

    Science.gov (United States)

    Rapp, A. D.; Bennartz, R.; Jiang, J. H.; Kato, S.; Olson, W. S.; Pinker, R. T.; Su, H.; Taylor, P. C.

    2014-12-01

    The eastern Pacific El Niño event in 2006-2007 and the central Pacific El Niño event during 2009-2010 exhibit opposite responses in the top of atmosphere (TOA) cloud radiative effects. These responses are driven by differences in large-scale circulation that result in significant low cloud anomalies in the subtropical southeastern Pacific. Both the vertical profile of cloud fraction and cloud water content are reduced during the eastern Pacific El Niño; however, the shift in the distribution of cloud characteristics and the physical processes underlying these changes need further analysis. The NASA Energy and Water Cycle Study (NEWS) Clouds and Radiation Working Group will use a synthesis of NEWS data products, A-Train satellite measurements, reanalysis, and modeling approaches to further explore the differences in the low cloud response to changes in the large-scale forcing, as well as try to understand the physical mechanism driving the observed changes in the low clouds for the 2006/07 and 2009/10 distinct El Niño events. The distributions of cloud macrophysical, microphysical, and radiative properties over the southeast Pacific will first be compared for these two events using a combination of MODIS, CloudSat/CALIPSO, and CERES data. Satellite and reanalysis estimates of changes in the vertical temperature and moisture profiles, lower tropospheric stability, winds, and surface heat fluxes are then used to identify the drivers for observed differences in the clouds and TOA radiative effects.

  14. Central amygdalar nucleus treated with orexin neuropeptides evoke differing feeding and grooming responses in the hamster.

    Science.gov (United States)

    Alò, Raffaella; Avolio, Ennio; Mele, Maria; Di Vito, Anna; Canonaco, Marcello

    2015-04-15

    Interaction of the orexinergic (ORXergic) neuronal system with the excitatory (glutamate, l-Glu) or the inhibitory (GABA) neurosignaling complexes evokes major homeostatic physiological events. In this study, effects of the two ORXergic neuropeptides (ORX-A/B) on their receptor (ORX-2R) expression changes were correlated to feeding and grooming actions of the hibernating hamster (Mesocricetus auratus). Infusion of the central amygdala nucleus (CeA) with ORX-A caused hamsters to consume notable quantities of food, while ORX-B accounted for a moderate increase. Interestingly the latter neuropeptide was responsible for greater frequencies of grooming with respect to both controls and the hamsters treated with ORX-A. These distinct behavioral changes turned out to be even greater in the presence of l-Glu agonist (NMDA) while the α1 GABAA receptor agonist (zolpidem, Zol) greatly reduced ORX-A-dependent feeding bouts. Moreover, ORX-A+NMDA mainly promoted greater ORX-2R expression levels with respect to ORX-A-treated hamsters while ORX-B+Zol was instead largely responsible for a down-regulatory trend. Overall, these features point to CeA ORX-2R sites as key sensory limbic elements capable of regulating eating and grooming responses, which may provide useful insights regarding the type of molecular mechanism(s) operating during feeding bouts. Copyright © 2015 Elsevier B.V. All rights reserved.

  15. Climate-Induced Larch Growth Response Within the Central Siberian Permafrost Zone

    Science.gov (United States)

    Kharuk, Viacheslav I.; Ranson, Kenneth J.; Im, Sergei T.; Petrov, Il'ya A.

    2015-01-01

    Aim: estimation of larch (Larix gmelinii) growth response to current climate changes. Location: permafrost area within the northern part of Central Siberia (approximately 65.8 deg N, 98.5 deg E). Method: analysis of dendrochronological data, climate variables, drought index SPEI, GPP (gross primary production) and EVI vegetation index (both Aqua/MODIS satellite derived), and soil water content anomalies (GRACE satellite measurements of equivalent water thickness anomalies, EWTA). Results: larch tree ring width (TRW) correlated with previous year August precipitation (r = 0.63), snow accumulation (r = 0.61), soil water anomalies (r = 0.79), early summer temperatures and water vapor pressure (r = 0.73 and r = 0.69, respectively), May and June drought index (r = 0.68-0.82). There are significant positive trends of TRW since late 1980s and GPP since the year 2000. Mean TRW increased by about 50%, which is similar to post-Little Ice Age warming. TRW correlated with GPP and EVI of larch stands (r = 0.68-0.69). Main conclusions: within the permafrost zone of central Siberia larch TRW growth is limited by early summer temperatures, available water from snowmelt, water accumulated within soil in the previous year, and permafrost thaw water. Water stress is one of the limiting factors of larch growth. Larch TRW growth and GPP increased during recent decades.

  16. An evaluation of the Australian Football League Central Australian Responsible Alcohol Strategy 2005-07.

    Science.gov (United States)

    Mentha, Ricky; Wakerman, Johne

    2009-12-01

    In 2004, the Australian Football League Central Australia (AFLCA) implemented the Responsible Alcohol Strategy (RAS), which aimed to decrease alcohol consumption at matches, and to promote healthy lifestyle messages to the youth of Central Australia participating in Australian Rules football. The evaluation adopted a pre- and post-implementation design to monitor a number of performance indicators. The evaluation analysed routinely collected data from AFLCA, its Security Company, Alice Springs Police Department and Alice Springs Hospital; we surveyed AFLCA staff, club officials and umpires; and undertook direct observation at AFLCA events. The volume of alcohol sold at matches decreased. Survey data indicate decreased alcohol related violence, improved spectator behaviour and decreased spectator attendances. Police data suggest declining alcohol-related and violent behaviours, but trends were not statistically significant. Alice Springs Hospital injury admission data indicate a non-significant interaction between year and season effect. In a community context of high alcohol consumption and high rates of interpersonal violence, the strategies implemented were successful in decreasing alcohol consumption and related undesirable behaviours at football games. However, these measures have resulted in unintended consequences: decreased numbers of spectators attending games, decreased canteen sales and falling sponsorship. The decreased revenue has raised serious issues about sustainability of the alcohol intervention, and stimulated discussions with government and others about strategies to maintain this important alcohol reduction policy.

  17. Effects of caffeine on the electrophysiological, cognitive and motor responses of the central nervous system.

    Science.gov (United States)

    Deslandes, A C; Veiga, H; Cagy, M; Piedade, R; Pompeu, F; Ribeiro, P

    2005-07-01

    Caffeine is the most consumed psychoactive substance in the world. The effects of caffeine have been studied using cognitive and motor measures, quantitative electroencephalography (qEEG) and event-related potentials. However, these methods are not usually employed in combination, a fact that impairs the interpretation of the results. The objective of the present study was to analyze changes in electrophysiological, cognitive and motor variables with the ingestion of caffeine, and to relate central to peripheral responses. For this purpose we recorded event-related potentials and eyes-closed, resting EEG, applied the Stroop test, and measured reaction time. Fifteen volunteers took caffeine (400 mg) or placebo in a randomized, crossover, double-blind design. A significant reduction of alpha absolute power over the entire scalp and of P300 latency at the Fz electrode were observed after caffeine ingestion. These results are consistent with a stimulatory effect of caffeine, although there was no change in the attention (Stroop) test or in reaction time. The qEEG seems to be the most sensitive index of the changes produced by caffeine in the central nervous system since it proved to be capable of detecting changes that were not evident in the tests of cognitive or motor performance.

  18. Effects of caffeine on the electrophysiological, cognitive and motor responses of the central nervous system

    Directory of Open Access Journals (Sweden)

    Deslandes A.C.

    2005-01-01

    Full Text Available Caffeine is the most consumed psychoactive substance in the world. The effects of caffeine have been studied using cognitive and motor measures, quantitative electroencephalography (qEEG and event-related potentials. However, these methods are not usually employed in combination, a fact that impairs the interpretation of the results. The objective of the present study was to analyze changes in electrophysiological, cognitive and motor variables with the ingestion of caffeine, and to relate central to peripheral responses. For this purpose we recorded event-related potentials and eyes-closed, resting EEG, applied the Stroop test, and measured reaction time. Fifteen volunteers took caffeine (400 mg or placebo in a randomized, crossover, double-blind design. A significant reduction of alpha absolute power over the entire scalp and of P300 latency at the Fz electrode were observed after caffeine ingestion. These results are consistent with a stimulatory effect of caffeine, although there was no change in the attention (Stroop test or in reaction time. The qEEG seems to be the most sensitive index of the changes produced by caffeine in the central nervous system since it proved to be capable of detecting changes that were not evident in the tests of cognitive or motor performance.

  19. Responses of calotropis procera and cassia senna to some soil factors in central Sudan

    International Nuclear Information System (INIS)

    Hayati, A. A.; Yahia, A. Y.

    2002-01-01

    The responses of calotropis procera and cassia senna to soil ph, Ca, Mg, K, Na, Mn, Fe, NH 4 -N and P were investigated in three sites in central Sudan, namely Omdurman, Wadelmajzob (Wad Medani) and Kosti. The investigation was carried out by chemical analysis of soil and pant samples collected randomly from 25 sampling points at each site. The data of the soil chemical analysis were analysed using the principal component analysis (PCA). The PCA reflected some what low range of variation in the distribution of the soil nutrient within each of the three investigated sites. Chemical analysis of C. procera and C. senna plants, collected from three investigated sites, showed that they have different levels of nutrients uptake. Although C. senna tends to have low mineral requirements compared with C. procera. it was completely absent from Kosti sit. This may be due to the acidity and high Mn levels at this site.(Author)

  20. Responses to migration: Tensions and ambiguities of churches in Pretoria Central and Mamelodi East

    Directory of Open Access Journals (Sweden)

    Wayne Renkin

    2017-09-01

    Full Text Available This article is a result of research being conducted to explore how churches in two regions of the City of Tshwane – Pretoria Central and Mamelodi East – respond to urban change and vulnerability. Both regions are deeply affected by urban migration patterns. Firstly, I will explore various forms of migration – transnational, rural-urban, urban–suburban and generational – and the causes of migration – social-economic and political – as experienced and described by the churches themselves. Secondly, I will seek to reflect on some of the tensions or ambiguities of how churches respond to migration, how the identity, self-understanding or locatedness of churches inform their responses to migration, and/or how churches and their identity are shaped by migration – commuter or local church, home or temporary church.

  1. Effects of duration of stay in temperate area on thermoregulatory responses to passive heat exposure in tropical south-east Asian males residing in Japan

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    Wijayanto Titis

    2012-09-01

    Full Text Available Abstract Background In this study, we investigated the effects of duration of stay in a temperate area on the thermoregulatory responses to passive heat exposure of residents from tropical areas, particularly to clarify whether they would lose their heat tolerance during passive heat exposure through residence in a temperate country, Japan. Methods We enrolled 12 males (mean ± SE age 25.7 ± 1.3 years from south-east Asian countries who had resided in Japan for a mean of 24.5 ± 5.04 months, and 12 Japanese males (age 24.1 ± 0.9 years. Passive heat exposure was induced through leg immersion in hot water (42°C for 60 minutes under conditions of 28°C air temperature and 50% relative humidity. Results Compared with the Japanese group, the tropical group displayed a higher pre-exposure rectal temperature (P P = 0.03. Additionally, the tropical group showed a tendency towards a lower total sweat rate (P = 0.06 and lower local sweat rate on the forehead (P = 0.07. The tropical group also had a significantly longer sweating onset time on the upper back (P = 0.04 compared with the Japanese groups. The tropical group who stayed in Japan for > 23 months sweated earlier on the forehead and upper back than those who stayed in Japan P P = 0.03 for the forehead and upper back, respectively. There was a positive correlation between duration of stay in Japan and total sweat rate (r = 0.58, P r = −0.73, P = 0.01 and on the upper back (r = −0.66, P = 0.02. Other physiological indices measured in this study did not show any difference between the subjects in the tropical group who had lived in Japan for a shorter time and those who had lived there for a longer time. Conclusions We conclude that the nature of heat acclimatization of the sweating responses to passive heat exposure that are acquired from long-term heat acclimatization is decayed by a stay in a temperate area, as shown

  2. Semiarid watershed response in central New Mexico and its sensitivity to climate variability and change

    Directory of Open Access Journals (Sweden)

    E. R. Vivoni

    2009-06-01

    Full Text Available Hydrologic processes in the semiarid regions of the Southwest United States are considered to be highly susceptible to variations in temperature and precipitation characteristics due to the effects of climate change. Relatively little is known about the potential impacts of climate change on the basin hydrologic response, namely streamflow, evapotranspiration and recharge, in the region. In this study, we present the development and application of a continuous, semi-distributed watershed model for climate change studies in semiarid basins of the Southwest US. Our objective is to capture hydrologic processes in large watersheds, while accounting for the spatial and temporal variations of climate forcing and basin properties in a simple fashion. We apply the model to the Río Salado basin in central New Mexico since it exhibits both a winter and summer precipitation regime and has a historical streamflow record for model testing purposes. Subsequently, we use a sequence of climate change scenarios that capture observed trends for winter and summer precipitation, as well as their interaction with higher temperatures, to perform long-term ensemble simulations of the basin response. Results of the modeling exercise indicate that precipitation uncertainty is amplified in the hydrologic response, in particular for processes that depend on a soil saturation threshold. We obtained substantially different hydrologic sensitivities for winter and summer precipitation ensembles, indicating a greater sensitivity to more intense summer storms as compared to more frequent winter events. In addition, the impact of changes in precipitation characteristics overwhelmed the effects of increased temperature in the study basin. Nevertheless, combined trends in precipitation and temperature yield a more sensitive hydrologic response throughout the year.

  3. Glial response in the central nervous system of cats with feline infectious peritonitis.

    Science.gov (United States)

    Mesquita, Leonardo P; Hora, Aline S; de Siqueira, Adriana; Salvagni, Fernanda A; Brandão, Paulo E; Maiorka, Paulo C

    2016-12-01

    The aim of the study was to evaluate central nervous system (CNS) lesions in non-effusive and effusive cases of feline infectious peritonitis (FIP) regarding aspects related to astrocytic and microglial reactions. Five necropsied cats that were naturally infected with FIP virus, confirmed by reverse transcriptase polymerase chain reaction and immunohistochemistry, with different intensities of CNS lesions, were studied. Brain and cerebellum were evaluated by light microscopy and immunohistochemistry for glial fibrillary acidic protein (GFAP) and vimentin to assess astrocytic morphology, and lectin histochemistry for Ricinus communis agglutinin-I (RCA-I) to detect microglia was performed to evaluate the glial response in the CNS of cats with FIP. An important astrocytic response in many areas of the CNS of all cats, including the periventricular areas of lateral ventricles and fourth ventricle, the molecular layer of the cerebellum and cerebral cortex, was visualized. This astrocytic reactivity was associated with areas of granulomatous or pyogranulomatous vasculitis/perivasculitis in most cases, and it was characterized by multifocal to coalescing astrocytosis and astrogliosis with an increase in the expression of intermediate filaments, such as GFAP. However, astrocytes exhibited strong vimentin expression in neuroparenchyma with severe inflammatory and necrotic changes, but GFAP expression was mild or absent in these cases. A microglial response was present only in severe lesions, and RCA-I expression was detected primarily in gitter cells and resting microglia. The present study indicates a strong astrocytic response, including the presence of many less differentiated vimentin-positive astrocytes and gitter cells positive for RCA-1 in severe lesions in the CNS of cats with FIP. © The Author(s) 2015.

  4. Testing bird response to roads on a rural environment: A case study from Central Italy

    Science.gov (United States)

    Morelli, Federico; Jerzak, Leszek; Pruscini, Fabio; Santolini, Riccardo; Benedetti, Yanina; Tryjanowski, Piotr

    2015-11-01

    The construction of roads is currently well spread in many parts of our world and impacts strongly on wildlife distribution. Some bird species avoid, while other prefer to be in the vicinity of these human structures. However, studies on roads effects on birds, in terms of strength or direction of these effects, are scarce. Therefore, in a study carried out in Central Italy we tested the responses of different bird species to roads at a local spatial scale, using generalized linear models (GLM). Analysis were conducted on a large dataset (more than 1400 sampled sites, mainly on rural environments). Both positive and negative effects of roads on birds were found for bird species of close or semi-close environments, while the negative effects of roads were negligible for bird species of open and semi-open environments. This fact suggest that roads can be a source of "functional heterogeneity" on semi-open environments, providing marginal habitats, hedgerows and residual vegetation typical of roadsides, offering breeding and feeding habitat for some bird species. The proposed methodology provide a useful explorative tool, in order to develop conservation policies to preserve the biodiversity, mainly in rural landscapes. The outputs of GLM can be used as inputs in ecological planning: direction and strength of the effects of roads on bird species are adequate to estimate the response of bird community, up front to the presence of new structures, or identifying which of them should be mitigated to reduce negative effects on the biodiversity.

  5. Immune responses in children infected with the pinworm Enterobius vermicularis in central Greece.

    Science.gov (United States)

    Patsantara, G G; Piperaki, E-T; Tzoumaka-Bakoula, C; Kanariou, M G

    2016-05-01

    Previous studies have suggested an immunomodulatory and even protective role for Enterobius vermicularis, the least pathogenic human intestinal helminth. Here, in a study using haematological and serological parameters, we tested a total of 215 children from central Greece, with a mean age of 8.39, of whom 105 (48.84%) were infected with E. vermicularis and 110 (51.16%) were matched healthy controls. In particular, we analysed eosinophil counts (EO), serum eosinophil cationic protein (ECP), total and specific serum immunoglobulin E (IgE) and the ECP/EO ratio. The atopic status and the potential occurrence of clinically expressed allergic diseases were both taken into account. Eosinophils, ECP and IgE were found to be higher in infected than in uninfected children, indicating a type-2 immune response activation during infection. Atopic infected children exhibited higher IgE levels compared to non-atopic ones. EO and ECP were found to be lower in atopic children who had a history of allergic disease than in those with no such history. The type-2 oriented immune response elicited against E. vermicularis could contribute to a balanced activation of the immune system in the examined children. Interestingly, although the atopic children showed a stronger activation, they did not exhibit any symptoms and, moreover, there seemed to be some indication of immunosuppression in those children with a positive history of allergic disease.

  6. Japan and the global environment

    International Nuclear Information System (INIS)

    Miller, A.S.; Moore, C.

    1993-01-01

    In many areas, the word most often used to describe Japanese policy is open-quotes enigma.close quotes In some ways, Japan's record on environmental policy also has elements of mystery and contradiction. On the one hand, Japan's history and culture often are associated with a reverence for nature. Indeed, Japan does lead the world in certain environmental areas, such as reduction of conventional air pollutants and compensation of air pollution victims. On the other hand, Japan has been widely criticized for its poor record in preserving its domestic environment, contribution to tropical deforestation, and unwillingness to protect endangered species. Today, the international community clamors for Japan to take its share of responsibility, as an economic superpower, for the global environment. To secure its place in world affairs, Japan slowly has begun to respond to this pressure on issues ranging from ivory importation to reduction of CFC emissions. There is some hope that the government's particular willingness to address global warming may be a sign of significant changes to come in Japanese environmental policy. However, international pressure remains on the many environmental issues Japan has yet to resolve, including tropical deforestation and financing of Third World development projects that harm the environment. Japan's environmental policy is most effective when government and industry cooperate to find technical solutions to environmental problems. Although in recent years Japan's energy consumption has risen sharply, the Japanese have developed numerous technologies to reduce pollution and increase economic growth by improving energy efficiency. It is in these technologies that Japan has made the greatest strides and has the most to offer the global environment

  7. Effects of aging on thermoregulatory responses and hormonal changes in humans during the four seasons in Japan

    Science.gov (United States)

    Sato, Maki; Kanikowska, Dominika; Sugenoya, Junichi; Inukai, Yoko; Shimizu, Yuuki; Nishimura, Naoki; Iwase, Satoshi

    2011-03-01

    Physiological functions are impaired in various organs in aged people, as manifest by, e.g., renal and cardiac dysfunction and muscle atrophy. The elderly are also at increased risk of both hypothermia and hyperthermia in extreme temperatures. The majority of those over 65 years old have elevated serum osmolality. Our hypothesis is that the elderly have suppressed osmolality control in different seasons compared to the young. Eight healthy young men and six healthy older men participated in this study. The experiments were performed during spring, summer, autumn and winter in Japan, with average atmospheric temperatures of 15-20°C in spring, 25-30°C in summer, 15-23°C in autumn and 5-10°C in winter. Each subject immersed his lower legs in warm water at 40°C for 30 min. Core (tympanic) temperature and sweat rate at chest were recorded continuously. Blood was taken pre-immersion to measure the concentrations of antidiuretic hormone, serum osmolality, plasma renin activity, angiotensin II, aldosterone, leptin, thyroid stimulating hormone, fT3 and fT4. The results suggested that the elderly have suppressed osmolality control compared to the young; osmolality was especially elevated in winter compared to the summer in elderly subjects. Therefore, particularly in the elderly, balancing fluid by drinking water should be encouraged to maintain euhydration status in winter.

  8. Response of phytoplankton and enhanced biogeochemical activity to an episodic typhoon event in the coastal waters of Japan

    Science.gov (United States)

    Tsuchiya, Kenji; Kuwahara, Victor S.; Yoshiki, Tomoko M.; Nakajima, Ryota; Shimode, Shinji; Kikuchi, Tomohiko; Toda, Tatsuki

    2017-07-01

    Daily field surveys were conducted at a coastal-shelf station in Sagami Bay, Japan after the passage of typhoon Malou in 2010 to evaluate the after-effect of a typhoon passage on the physical-chemical environment, phytoplankton bloom formation and microbial processes within and below the euphotic layer. The passage of Malou induced an abrupt decrease in salinity and increased loading of nutrients to the euphotic layer. Dinoflagellates dominated the phytoplankton community at the surface, whereas diatoms dominated below the surface just after the passage of Malou. Four days later, the dominant dinoflagellate taxa at the surface changed from Protoperidinium spp. to Prorocentrum spp. and Ceratium spp., indicating a dinoflagellate community succession from heterotrophic to autotrophic functional groups. Five days after passage, the dominant phytoplankton taxa shifted from dinoflagellates to diatom groups of Chaetoceros spp. and Cerataulina spp. throughout the water column. Below the euphotic layer, there were increases in diatom frustules, mainly composed of Chaetoceros spp. and Cerataulina spp., bacterial abundance and NH4+ concentrations. Diatom carbon biomass contributed to approximately half of particulate organic carbon (POC) below the euphotic layer, suggesting a significant contribution of diatoms to POC sinking flux after the passage of a typhoon. Bacterial abundance was positively correlated to both phaeopigment concentrations (p affect biogeochemical activities within and below the euphotic layer in temperate coastal waters.

  9. Study of the response of the ATLAS central calorimeter to pions of energies from 3 to 9 GeV

    International Nuclear Information System (INIS)

    Abat, E.; Abdallah, J.M.; Addy, T.N.; Adragna, P.; Aharrouche, M.; Ahmad, A.; Akesson, T.P.A.; Aleksa, M.; Alexa, C.; Anderson, K.; Anghinolfi, F.; Antonaki, A.; Arabidze, G.; Arik, E.; Baker, O.K.; Banfi, D.; Baron, S.; Beck, H.P.

    2009-01-01

    A fully instrumented slice of the ATLAS central detector was exposed to test beams from the SPS (Super Proton Synchrotron) at CERN in 2004. In this paper, the response of the central calorimeters to pions with energies in the range between 3 and 9 GeV is presented. The linearity and the resolution of the combined calorimetry (electromagnetic and hadronic calorimeters) was measured and compared to the prediction of a detector simulation program using the toolkit Geant 4.

  10. Study of the response of the ATLAS central calorimeter to pions of energies from 3 to 9 GeV

    Energy Technology Data Exchange (ETDEWEB)

    Abat, E [Bogazici University, Faculty of Sciences, Department of Physics, TR - 80815 Bebek-Istanbul (Turkey); Abdallah, J M [Institut de Fisica d' Altes Energies, IFAE, Universitat Autonoma de Barcelona, Edifici Cn, ES - 08193 Bellaterra, Barcelona (Spain); Addy, T N [Hampton University, Department of Physics, Hampton VA 23668 (United States); Adragna, P [Queen Mary, University of Landon, Mile End Road, E1 4NS London, United Kingdoom (United Kingdom); Aharrouche, M [Universitaet Mainz, Institut fuer Physik, Staudinger Weg 7, DE 55099 (Germany); Ahmad, A [Department of Physics and Astronomy, Stony Brook, NY 11794-3800 (United States); Akesson, T P.A. [Lunds universitet, Naturvetenskapliga fakulteten, Fysiska institutionen, Box 118, SE - 221 00, Lund (Sweden); Aleksa, M [European Laboratory for Particle Physics (CERN), CH-1211 Geneva 23 (Switzerland); Alexa, C [National Institute of Physics and Nuclear Engineering (Bucharest -IFIN-HH), P.O. Box MG-6, R-077125 Bucharest (Romania); Anderson, K [University of Chicago, Enrico Fermi Institute, 5640 S. Ellis Avenue, Chicago, IL 60637 (United States); Anghinolfi, F [European Laboratory for Particle Physics (CERN), CH-1211 Geneva 23 (Switzerland); Antonaki, A; Arabidze, G [University of Athens, Nuclear and Particle Physics Department of Physics, Panepistimiopouli Zografou, GR 15771 Athens (Greece); Arik, E [Bogazici University, Faculty of Sciences, Department of Physics, TR - 80815 Bebek-Istanbul (Turkey); Baker, O K [Yale University, Department of Physics , PO Box 208121, New Haven, CT06520-8121 (United States); Banfi, D [Universita di Milano , Dipartimento di Fisica and INFN, via Celoria 16, IT - 20133 Milano (Italy); Baron, S [European Laboratory for Particle Physics (CERN), CH-1211 Geneva 23 (Switzerland); Beck, H P [University of Bern, Laboratory for High Energy Physics, Sidlerstrasse 5, CH - 3012 Bern (Switzerland)

    2009-08-11

    A fully instrumented slice of the ATLAS central detector was exposed to test beams from the SPS (Super Proton Synchrotron) at CERN in 2004. In this paper, the response of the central calorimeters to pions with energies in the range between 3 and 9 GeV is presented. The linearity and the resolution of the combined calorimetry (electromagnetic and hadronic calorimeters) was measured and compared to the prediction of a detector simulation program using the toolkit Geant 4.

  11. Responses of Montane Forest to Climate Variability in the Central Himalayas of Nepal

    Directory of Open Access Journals (Sweden)

    Janardan Mainali

    2015-02-01

    Full Text Available Climate changes are having dramatic ecological impacts in mid- to high-latitude mountain ranges where growth conditions are limited by climatic variables such as duration of growing season, moisture, and ambient temperature. We document patterns of forest vegetative response for 5 major alpine forest communities to current climate variability in the central Himalayas of Nepal to provide a baseline for assessment of future changes, as well as offer some insight into the trajectory of these changes over time. We used mean monthly surface air temperature and rainfall and the monthly averaged normalized difference vegetation index (NDVI to compare relative vegetation productivity among forest types and in relation to both climatic variables. Because changes in temperature and precipitation are directly manifested as changes in phenology, we examined current vegetative responses to climate variability in an effort to determine which climate variable is most critical for different alpine forest types. Our results show that correlations differ according to vegetation type and confirm that both precipitation and temperature affect monthly NDVI values, though more significant correlations were found with temperature data. The temperature response was more consistent because at the maximum increased temperatures, there was still an ongoing increase in vegetative vigor. This indicates that temperature is still the major limiting factor for plant growth at higher-elevation sites. This part of the Himalayas has abundant moisture, and some forest types are already saturated in terms of growth in relation to precipitation. Clear increases in productivity are documented on the upper treeline ecotones, and these systems are likely to continue to have increasing growth rates.

  12. Impact of the Innate Immune Response in the Actions of Ethanol on the Central Nervous System.

    Science.gov (United States)

    Montesinos, Jorge; Alfonso-Loeches, Silvia; Guerri, Consuelo

    2016-11-01

    The innate immune response in the central nervous system (CNS) participates in both synaptic plasticity and neural damage. Emerging evidence from human and animal studies supports the role of the neuroimmune system response in many actions of ethanol (EtOH) on the CNS. Research studies have shown that alcohol stimulates brain immune cells, microglia, and astrocytes, by activating innate immune receptors Toll-like receptors (TLRs) and NOD-like receptors (inflammasome NLRs) triggering signaling pathways, which culminate in the production of pro-inflammatory cytokines and chemokines that lead to neuroinflammation. This review focuses on evidence that indicates the participation of TLRs and the inflammasome NLRs signaling response in many effects of EtOH on the CNS, such as neuroinflammation associated with brain damage, cognitive and behavioral dysfunction, and adolescent brain development alterations. It also reviews findings that indicate the role of TLR4-dependent signaling immune molecules in alcohol consumption, reward, and addiction. The research data suggest that overactivation of TLR4 or NLRs increases pro-inflammatory cytokines and mediators to cause neural damage in the cerebral cortex and hippocampus, while modest TLR4 activation, along with the generation of certain cytokines and chemokines in specific brain areas (e.g., amygdala, ventral tegmental area), modulate neurotransmission, alcohol drinking, and alcohol rewards. Elimination of TLR4 and NLRP3 abolishes many neuroimmune effects of EtOH. Despite much progress being made in this area, there are some research gaps and unanswered questions that this review discusses. Finally, potential therapies that target neuroimmune pathways to treat neuropathological and behavioral consequences of alcohol abuse are also evaluated. Copyright © 2016 by the Research Society on Alcoholism.

  13. Age dating and flow path evaluation of groundwater by SF6 and microbe in the foot of Mt. Fuji, central Japan

    Science.gov (United States)

    Yamamoto, Chisato; Tsujimura, Maki; Kato, Kenji; Nagaosa, Kazuyo; Sakakibara, Koichi; Umei, Yohei; Ohara, Kazuma

    2016-04-01

    A variety of industries are developed at the foot of volcanic mountains in Japan and the groundwater is major source for industrial activity in those regions. The age of groundwater has been estimated to be from 10 to 30 years in Mt. Fuji regions by using 36Cl and 3H. However, the age has not been evaluated using SF6 with higher time resolution in these regions. Also, the total number of prokaryotes shows a specific value in each spring water, suggesting different path and age of the groundwater. Therefore, we aim to estimate residence time and the groundwater flow in three dimensions using the multi-tracers approach; CFCs, SF6, the total number of prokaryotes, the stable isotopes of oxygen-18, deuterium. We collected totally 25 spring water samples in Mt. Fuji and analyzed concentration of inorganic ions, the stable isotopes of oxygen-18, deuterium, CFCs, SF6. The apparent age of the spring water was estimated to be ranging from 4 to 19 years at the foot of Mt. Fuji. These results are reasonable as considering the existed age data by36Cl (Tosaki, 2008) in this region. The spring water with younger age tends to show higher total number of prokaryotes, suggesting that the groundwater flows dominantly through the shallow and young lava with the higher total number of prokaryotes, leads to younger age. Focusing on a specific spring water, the seasonal change of SF6 and total number of prokaryotes were monitored. The spring water showed a younger age and higher total number of prokaryotes during the high water flow season, whereas it showed an older age and lower total number of prokaryotes. Therefore, the total number of prokaryotes shows a good negative correlation with the residence time of the spring/ groundwater in space and time. This shows a possibility that the total number of prokaryotes could be a useful tracer of groundwater for time and space in the three dimensions information.

  14. Central nervous system effects of the second-generation antihistamines marketed in Japan--review of inter-drug differences using the proportional impairment ratio (PIR-.

    Directory of Open Access Journals (Sweden)

    Tatsuya Isomura

    Full Text Available BACKGROUND: Second-generation antihistamines (AHs have, in general, fewer sedative effects than the first-generation. However, important inter-drug differences remain in the degree of cognitive and/or psychomotor impairment. The extent to which a particular compound causes disruption can be conveniently compared, to all other AHs, using the Proportional Impairment Ratio (PIR. Although the PIR can differentiate the relative impairment caused by individual drugs, there is no indication of the reliability of the ratios obtained. OBJECTIVE: To calculate the PIRs -together with 95% confidence intervals (CIs, as an index of reliability- and compare AHs currently, or soon to be, available in Japan, with respect to their intrinsic capacity to cause impairment. METHODS: Results from studies of cetirizine, desloratadine, ebastine, fexofenadine, levocetirizine, loratadine, mequitazine, and olopatadine were included in the PIR calculations. All data utilised came from crossover studies in healthy volunteers which were randomised and placebo and positive-internal controlled. Existing databases from studies reporting the sedative effects of AHs on objective (speed, accuracy, memory and subjective (feeling psychometrics were augmented, via results from suitable studies published after the previous reviews. The null value for a PIR was one. RESULTS: A total of 45 studies were finally included for this review. Of the AHs assessed, fexofenadine, ebastine, and levocetirizine showed a PIR for objective tests of 0. However, only fexofenadine (PIR = 0.49 had an upper limit of the 95% CI of less than 1. Fexofenadine, levocetirizine, desloratadine, olopatadine, loratadine, and mequitazine all had a PIR for subjective ratings of 0, but the upper limits of the 95% CIs were all in excess of 1, although fexofenadine (PIR = 2.57 was the lowest. CONCLUSIONS: The results show that there are differences between second-generation AHs in the extent of sedation produced

  15. Paleomagnetic direction and paleointensity variations during the Matuyama-Brunhes polarity transition from a marine succession in the Chiba composite section of the Boso Peninsula, central Japan

    Science.gov (United States)

    Okada, Makoto; Suganuma, Yusuke; Haneda, Yuki; Kazaoka, Osamu

    2017-03-01

    The youngest geomagnetic polarity reversal, the Matuyama-Brunhes (M-B) boundary, provides an important plane of data for sediments, ice cores, and lavas. The geomagnetic field intensity and directional changes that occurred during the reversal also provide important information for understanding the dynamics of the Earth's outer core, which generates the magnetic field. However, the reversal process is relatively rapid in terms of the geological timescale; therefore, adequate temporal resolution of the geomagnetic field record is essential for addressing these topics. Here, we report a new high-resolution paleomagnetic record from a continuous marine succession in the Chiba composite section of the Kokumoto Formation of the Kazusa Group, Japan, that reveals detailed behaviors of the virtual geomagnetic poles (VGPs) and relative paleointensity changes during the M-B polarity transition. The resultant relative paleointensity and VGP records show a significant paleointensity minimum near the M-B boundary, which is accompanied by a clear "polarity switch." A newly obtained high-resolution oxygen isotope chronology for the Chiba composite section indicates that the M-B boundary is located in the middle of marine isotope stage (MIS) 19 and yields an age of 771.7 ka for the boundary. This age is consistent with those based on the latest astronomically tuned marine and ice core records and with the recalculated age of 770.9 ± 7.3 ka deduced from the U-Pb zircon age of the Byk-E tephra. To the best of our knowledge, our new paleomagnetic data represent one of the most detailed records on this geomagnetic field reversal that has thus far been obtained from marine sediments and will therefore be key for understanding the dynamics of the geomagnetic dynamo and for calibrating the geological timescale.[Figure not available: see fulltext.

  16. Hominin responses to environmental changes during the Middle Pleistocene in central and southern Italy

    Science.gov (United States)

    Orain, R.; Lebreton, V.; Russo Ermolli, E.; Sémah, A.-M.; Nomade, S.; Shao, Q.; Bahain, J.-J.; Thun Hohenstein, U.; Peretto, C.

    2013-03-01

    The palaeobotanical record of early Palaeolithic sites from Western Europe indicates that hominins settled in different kinds of environments. During the "mid-Pleistocene transition (MPT)", from about 1 to 0.6 Ma, the transition from 41- to 100-ka dominant climatic oscillations, occurring within a long-term cooling trend, was associated with an aridity crisis which strongly modified the ecosystems. Starting from the MPT the more favourable climate of central and southern Italy provided propitious environmental conditions for long-term human occupations even during the glacial times. In fact, the human strategy of territory occupation was certainly driven by the availabilities of resources. Prehistoric sites such as Notarchirico (ca. 680-600 ka), La Pineta (ca. 600-620 ka), Guado San Nicola (ca. 380-350 ka) or Ceprano (ca. 345-355 ka) testify to a preferential occupation of the central and southern Apennines valleys during interglacial phases, while later interglacial occupations were oriented towards the coastal plains, as attested by the numerous settlements of the Roma Basin (ca. 300 ka). Faunal remains indicate that human subsistence behaviours benefited from a diversity of exploitable ecosystems, from semi-open to closed environments. In central and southern Italy, several palynological records have already illustrated the regional- and local-scale vegetation dynamic trends. During the Middle Pleistocene climate cycles, mixed mesophytic forests developed during the interglacial periods and withdrew in response to increasing aridity during the glacial episodes. New pollen data from the Boiano Basin (Molise, Italy) attest to the evolution of vegetation and climate between MIS 13 and 9 (ca. 500 to 300 ka). In this basin the persistence of high edaphic humidity, even during the glacial phases, could have favoured the establishment of a refuge area for the arboreal flora and provided subsistence resources for the animal and hominin communities during the Middle

  17. Hominin responses to environmental changes during the Middle Pleistocene in central and southern Italy

    Directory of Open Access Journals (Sweden)

    R. Orain

    2013-03-01

    Full Text Available The palaeobotanical record of early Palaeolithic sites from Western Europe indicates that hominins settled in different kinds of environments. During the "mid-Pleistocene transition (MPT", from about 1 to 0.6 Ma, the transition from 41- to 100-ka dominant climatic oscillations, occurring within a long-term cooling trend, was associated with an aridity crisis which strongly modified the ecosystems. Starting from the MPT the more favourable climate of central and southern Italy provided propitious environmental conditions for long-term human occupations even during the glacial times. In fact, the human strategy of territory occupation was certainly driven by the availabilities of resources. Prehistoric sites such as Notarchirico (ca. 680–600 ka, La Pineta (ca. 600–620 ka, Guado San Nicola (ca. 380–350 ka or Ceprano (ca. 345–355 ka testify to a preferential occupation of the central and southern Apennines valleys during interglacial phases, while later interglacial occupations were oriented towards the coastal plains, as attested by the numerous settlements of the Roma Basin (ca. 300 ka. Faunal remains indicate that human subsistence behaviours benefited from a diversity of exploitable ecosystems, from semi-open to closed environments. In central and southern Italy, several palynological records have already illustrated the regional- and local-scale vegetation dynamic trends. During the Middle Pleistocene climate cycles, mixed mesophytic forests developed during the interglacial periods and withdrew in response to increasing aridity during the glacial episodes. New pollen data from the Boiano Basin (Molise, Italy attest to the evolution of vegetation and climate between MIS 13 and 9 (ca. 500 to 300 ka. In this basin the persistence of high edaphic humidity, even during the glacial phases, could have favoured the establishment of a refuge area for the arboreal flora and provided subsistence resources for the animal and hominin communities

  18. The Japan HOspice and Palliative Care Evaluation Study 3: Study Design, Characteristics of Participants and Participating Institutions, and Response Rates.

    Science.gov (United States)

    Aoyama, Maho; Morita, Tatsuya; Kizawa, Yoshiyuki; Tsuneto, Satoru; Shima, Yasuo; Miyashita, Mitsunori

    2017-08-01

    This article describes the whole picture of Japan HOspice and Palliative Care Evaluation Study 3 (J-HOPE3 Study) including study design and demographic data. The aims of the J-HOPE3 study were to (1) evaluate the process, structure, and outcome of palliative care in the following care settings: acute hospitals, inpatient hospice/palliative care units (PCUs), and home hospice services; (2) examine bereaved family members' self-reported psychosocial conditions, such as grief and depression, as bereavement outcomes; (3) provide data to ensure and improve the quality of care provided by participating institutions through feedback concerning results for each institution; and (4) perform additional studies to explore specific clinical research questions. We conducted a cross-sectional, anonymous, self-report questionnaire survey involving patients' bereaved family members in 20 acute hospitals, 133 PCUs, and 22 home hospice services between May and July 2014. Two types of questionnaires were used: main and specific studies questionnaires. The questionnaire was sent to totally 13 584, and 10 157 returned the questionnaire. The analysis included 9126 family members' questionnaires from acute hospitals, PCUs, and home hospice services. Respondents' average age was 61.6 years, 55% were women, and 40% had been married to the deceased. With respect to the characteristics of participating institutions, most institutions did not have religious affiliations, and most PCUs and home hospice services provided bereavement care. These results of the analysis of common and additional questionnaires could play an important role in clinical settings, quality improvement, research, and public accountability.

  19. Identification of tsunami deposits considering the tsunami waveform: An example of subaqueous tsunami deposits in Holocene shallow bay on southern Boso Peninsula, Central Japan

    Science.gov (United States)

    Fujiwara, Osamu; Kamataki, Takanobu

    2007-08-01

    This study proposes a tsunami depositional model based on observations of emerged Holocene tsunami deposits in outcrops located in eastern Japan. The model is also applicable to the identification of other deposits, such as those laid down by storms. The tsunami deposits described were formed in a small bay of 10-20-m water depth, and are mainly composed of sand and gravel. They show various sedimentary structures, including hummocky cross-stratification (HCS) and inverse and normal grading. Although, individually, the sedimentary structures are similar to those commonly found in storm deposits, the combination of vertical stacking in the tsunami deposits makes a unique pattern. This vertical stacking of internal structures is due to the waveform of the source tsunamis, reflecting: 1) extremely long wavelengths and wave period, and 2) temporal changes of wave sizes from the beginning to end of the tsunamis. The tsunami deposits display many sub-layers with scoured and graded structures. Each sub-layer, especially in sandy facies, is characterized by HCS and inverse and normal grading that are the result of deposition from prolonged high-energy sediment flows. The vertical stack of sub-layers shows incremental deposition from the repeated sediment flows. Mud drapes cover the sub-layers and indicate the existence of flow-velocity stagnant stages between each sediment flow. Current reversals within the sub-layers indicate the repeated occurrence of the up- and return-flows. The tsunami deposits are vertically divided into four depositional units, Tna to Tnd in ascending order, reflecting the temporal change of wave sizes in the tsunami wave trains. Unit Tna is relatively fine-grained and indicative of small tsunami waves during the early stage of the tsunami. Unit Tnb is a protruding coarse-grained and thickest-stratified division and is the result of a relatively large wave group during the middle stage of the tsunami. Unit Tnc is a fine alternation of thin sand

  20. The origin of a coarse lithic breccia in the 34 ka caldera-forming Sounkyo eruption, Taisetsu volcano group, central Hokkaido, Japan

    Science.gov (United States)

    Yasuda, Y.; Suzuki-Kamata, K.

    2018-05-01

    The 34 ka Sounkyo eruption produced 7.6 km3 of tephra ( 5 km3 DRE) as fallout, ignimbrite, and lithic breccia units, forming a small, 2-km-diameter summit caldera in the Taisetsu volcano group, Japan. The Sounkyo eruption products are made up of five eruptive units (SK-A to -E) in proximal regions, corresponding to the distal deposits, a 1- to 2-m-thick pumice fallout and the Px-type ignimbrite up to 220 m thick. The eruption began with a fallout phase, producing unstable low eruption columns during the earlier phase to form a 27-m-thick, unstratified and ungraded, coarse lithic breccia (SK-C). The failure in turn choked the conduit, and then the eruption stopped. After a short eruptive hiatus, the eruption resumed with a short-lived fall phase, establishing an eruption column up to 16 km high and producing a <6-m-thick scoria fallout (SK-D). Finally, the eruption ended with the generation of PDCs by eruption column collapse to form a 5- to 15-m-thick ignimbrite in the proximal area (SK-E). Volume relationships between the caldera, ejected magma, and ejected lithic fragments suggest that the caldera was not essentially formed by caldera collapse but, instead, by vent widening as a consequence of explosive erosion and failure of the shallow conduit. The dominance of shallow-origin volcanic rocks in the lithic fraction throughout the Sounkyo eruption products implies the development of a flaring funnel-shaped vent. Hence, the occurrence of lithic breccias within small caldera-forming eruption products does not necessarily reflect either the existence or the timing of caldera collapse, as commonly assumed in literature. Lithic breccias commonly overlie climactic ignimbrite/fallout deposits in small caldera-forming eruptions, and an alternative explanation is that this reflects the collapse of the shallow conduit after an eruption climax, whose walls had been highly fractured and had become unstable owing to progressive erosion.

  1. Community response to construction noise in three central cities of Zhejiang province, China.

    Science.gov (United States)

    Liu, Yong; Xia, Bo; Cui, Caiyun; Skitmore, Martin

    2017-11-01

    As a common source of environmental noise in China and many developing countries worldwide, construction work provokes many complaints and deterioration in acoustic climate quality. This paper describes research to obtain an improved understanding of people's community response to, and evaluation of, construction noise in three central cities of Zhejiang province, China. This involved carrying out a social survey using standard questionnaires developed by the International Commission on Biological Effects of Noise (ICBEN). A dose-response relationship model is established using a quadratic polynomial regression analysis based on construction noise exposure measurements from 40 construction sites in Hangzhou, Ningbo and Wenzhou. The results of the study indicate that the majority of people have a negative attitude to construction noise; the noise ranges between 60 dB and 80 dB (compared with 50 dB-70 dB traffic noise in Tianjin), with the percentage of highly annoyed people affected increasing from 15%-20% to 30%-40% over the range. There also different levels of annoyance depending on the time of day, and the location and activities of those affected. Other cultural differences are also apparent both between Ningbo/Wenzhou and the more urbane citizens of Hangzhou, and the Chinese people and their more noise-tolerant EU and Vietnam counterparts. The findings of this study provide a new perspective for the study of construction noise that can help local governments have an improved understanding of how residents react to construction noise for the purpose of selecting construction noise-mitigation projects and introducing construction noise-control regulations. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Foliage response of young central European oaks to air warming, drought and soil type.

    Science.gov (United States)

    Günthardt-Goerg, M S; Kuster, T M; Arend, M; Vollenweider, P

    2013-01-01

    Three Central European oak species, with four provenances each, were experimentally tested in 16 large model ecosystem chambers for their response to passive air warming (AW, ambient +1-2 °C), drought (D, -43 to -60% irrigation) and their combination (AWD) for 3 years on two forest soil types of pH 4 or 7. Throughout the entire experiment, the influence of the different ambient and experimental climates on the oak trees was strong. The morphological traits of the Quercus species were affected in opposing ways in AW and D treatments, with a neutral effect in the AWD treatment. Biochemical parameters and LMA showed low relative plasticity compared to the morphological and growth parameters. The high plasticity in physiologically important parameters of the three species, such as number of intercalary veins or leaf size, indicated good drought acclimation properties. The soil type influenced leaf chlorophyll concentration, C/N and area more than drought, whereas foliage mass was more dependent on drought than on soil type. Through comparison of visible symptom development with the water deficits, a drought tolerance threshold of -1.3 MPa was determined. Although Q. pubescens had xeromorphic leaf characteristics (small leaf size, lower leaf water content, high LMA, pilosity, more chlorophyll, higher C/N) and less response to the treatments than Q. petraea and Q. robur, it suffered more leaf drought injury and shedding of leaves than Q. petraea. However, if foliage mass were used as the criterion for sustainable performance under a future climate, Q. robur would be the most appropriate species. © 2012 German Botanical Society and The Royal Botanical Society of the Netherlands.

  3. Central hemodynamic responses during serial exercise tests in heart failure patients using implantable hemodynamic monitors.

    Science.gov (United States)

    Ohlsson, A; Steinhaus, D; Kjellström, B; Ryden, L; Bennett, T

    2003-06-01

    Exercise testing is commonly used in patients with congestive heart failure for diagnostic and prognostic purposes. Such testing may be even more valuable if invasive hemodynamics are acquired. However, this will make the test more complex and expensive and only provides information from isolated moments. We studied serial exercise tests in heart failure patients with implanted hemodynamic monitors allowing recording of central hemodynamics. Twenty-one NYHA Class II-III heart failure patients underwent maximal exercise tests and submaximal bike or 6-min hall walk tests to quantify their hemodynamic responses and to study the feasibility of conducting exercise tests in patients with such devices. Patients were followed for 2-3 years with serial exercise tests. During maximal tests (n=70), heart rate increased by 52+/-19 bpm while S(v)O(2) decreased by 35+/-10% saturation units. RV systolic and diastolic pressure increased 29+/-11 and 11+/-6 mmHg, respectively, while pulmonary artery diastolic pressure increased 21+/-8 mmHg. Submaximal bike (n=196) and hall walk tests (n=172) resulted in S(v)O(2) changes of 80 and 91% of the maximal tests, while RV pressures ranged from 72 to 79% of maximal responses. An added potential value of implantable hemodynamic monitors in heart failure patients may be to quantitatively determine the true hemodynamic profile during standard non-invasive clinical exercise tests and to compare that to hemodynamic effects of regular exercise during daily living. It would be of interest to study whether such information could improve the ability to predict changes in a patient's clinical condition and to improve tailoring patient management.

  4. Wind Energy Japan

    Energy Technology Data Exchange (ETDEWEB)

    Komatsubara, Kazuyo [Embassy of the Kingdom of the Netherlands, Tokyo (Japan)

    2012-06-15

    An overview is given of wind energy in Japan: Background; Wind Energy in Japan; Japanese Wind Energy Industry; Government Supports; Useful Links; Major Japanese Companies; Profiles of Major Japanese Companies; Major Wind Energy Projects in Japan.

  5. Future accelerators in Japan

    International Nuclear Information System (INIS)

    Toge, Nobu

    1993-01-01

    This paper presents a brief report on the present status of future accelerator projects at the National Laboratory for High Energy Physics (KEK), Japan. The KEK laboratory has been successfully operating the TRISTAN accelerator complex since 1986. It consists of a 2.5 GeV electron/positron linac, an 8 GeV Accumulation Ring (AR) and a 29 GeV Main Ring (MR). Concurrently with this operation, in response to recommendations by the Japanese High Energy Physics Committee, survey studies have been continued on new accelerator facilities at KEK. They have two major future projects, namely, the asymmetric e + e - B-factory based on TRISTAN (TRISTAN-II) and the Japan Linear Collider (JLC). The purpose of this paper is to outline those research activities and to present an update on their status

  6. Surface Mining and Reclamation Effects on Flood Response of Watersheds in the Central Appalachian Plateau Region

    Science.gov (United States)

    Ferrari, J. R.; Lookingbill, T. R.; McCormick, B.; Townsend, P. A.; Eshleman, K. N.

    2009-01-01

    Surface mining of coal and subsequent reclamation represent the dominant land use change in the central Appalachian Plateau (CAP) region of the United States. Hydrologic impacts of surface mining have been studied at the plot scale, but effects at broader scales have not been explored adequately. Broad-scale classification of reclaimed sites is difficult because standing vegetation makes them nearly indistinguishable from alternate land uses. We used a land cover data set that accurately maps surface mines for a 187-km2 watershed within the CAP. These land cover data, as well as plot-level data from within the watershed, are used with HSPF (Hydrologic Simulation Program-Fortran) to estimate changes in flood response as a function of increased mining. Results show that the rate at which flood magnitude increases due to increased mining is linear, with greater rates observed for less frequent return intervals. These findings indicate that mine reclamation leaves the landscape in a condition more similar to urban areas rather than does simple deforestation, and call into question the effectiveness of reclamation in terms of returning mined areas to the hydrological state that existed before mining.

  7. Canopy Transpiration and Stomatal Responses to Prolonged Drought by a Dominant Desert Species in Central Asia

    Directory of Open Access Journals (Sweden)

    Daxing Gu

    2017-06-01

    Full Text Available In arid and semiarid lands, canopy transpiration and its dynamics depend largely on stomatal sensitivity to drought. In this study, the sap flow of a dominant species, Haloxylon ammodendron growing in Central Asian deserts, was monitored using Granier-type sensors, from which the canopy stomatal conductance was derived. The responses of canopy transpiration and stomatal conductance to environmental variables during the second half of the growing season, when annual prolonged drought occurred, was analyzed for four continuous years, from 2013 to 2016. A soil water content (SWC of 3% was identified as the lower soil water threshold for this species, below which the plant lost the ability for stomatal regulation on water loss and suffered the risk of mortality. Above this threshold, the sensitivity of canopy transpiration to vapor pressure deficit, VPD (K, was linearly correlated with SWC, which mainly resulted from different stomatal behaviors at varying drought intensities. Stomatal sensitivity to VPD (m/Gsref increased linearly with soil moisture deficit, inducing a shift from more anisohydric to a more isohydric stomatal behavior. The flexibility of stomatal behavior regarding soil drought was one key element facilitating the survival of H. ammodendron in such an extreme dry environment.

  8. Corporate Social Responsibility and Financial Performance in the Airline Industry in Central and Eastern Europe

    Directory of Open Access Journals (Sweden)

    Roman Asatryan

    2014-01-01

    Full Text Available This paper contributes to the knowledge on corporate social responsibility (CSR initiatives of by businesses and its ability to influence their financial performance. Consequently, the main objective is to examine the relationship between CSR and financial performance in the airline industry in Central and Eastern Europe. The paper does not attempt to establish causality between CŚR and financial performance. The paper attempts to contribute to the existing knowledge in the field by examining the extent to which CSR relates to financial performance of airline firms. A sample of 20 audited financial statements of airline firms were selected randomly. The study analyzed the impact of CSR activities on the financial performance of firms. The Return on Equity (ROE and Return on Assets (ROA were used as indicators to measure financial performance of firms whiles the independent variables were Community Performance (CP, Environment Management System (EMS and Employee Relations (ER. The study found that there is a significant positive relationship between CSR initiatives and financial performance measures. More specifically, there was found to be a positive relationship between the independent variables of CSR thus, CP, EMS and ER and the financial performance of airline firms in terms of the ROE and ROA.

  9. The Tokyo Trial and the Question of Colonial Responsibility: Korean Reactions to Allied Justice in Occupied Japan

    Directory of Open Access Journals (Sweden)

    Young-hwan Chong

    2017-02-01

    Full Text Available This article examines how the zainichi Korean media and organizations responded to the Tokyo Trial and its pursuit of war responsibility. Their critiques of the Tokyo Trial often presented a critical insight from the perspective of anti-colonialism. Zainichi Koreans correctly questioned the absence of colonial responsibility in the pursuit of justice and war responsibility in the trial. In this sense, the problems and limits of the Tokyo Trial that scholars started to “discover” in the 1970s had already been discussed by some zainichi Koreans in the late 1940s. By delving into previously under-explored historical sources, particularly the numerous newspapers published by zainichi Korean groups during the occupation period, this article demonstrates how zainichi Korean critics understood the limits of the Tokyo Trial beyond the binary of “victors' justice” and “the judgment of civilization.”

  10. Short-Term Response of Sasa Dwarf Bamboo to a Change of Soil Nitrogen Fertility in a Forest Ecosystem in Northern Hokkaido, Japan

    Directory of Open Access Journals (Sweden)

    Tsunehiro Watanabe

    2016-04-01

    Full Text Available In forest ecosystems, a change of soil nitrogen (N cycling after disturbance is regulated by various factors. Sasa dwarf bamboo (hereafter referred to as Sasa is an understory plant that grows thickly on the forest floor in northern Hokkaido, Japan. However, the ecosystem function of Sasa after disturbances in the soil N cycling is not fully understood. The purpose of this study was to determine the short-term response of Sasa to a change of soil N fertility. Biomass, litterfall, litter decomposition, soil N pool, and N leaching from soil were measured in control, and low- (5 g N m−2 year−1 and high-N (15 g N m−2 year−1 addition plots. Sasa immobilized much N as the soil N fertility increased. However, the leaf N concentration in aboveground biomass did not increase, suggesting that the N in leaves was maintained because of the increase of leaf biomass. As a result, the decomposition and mineralization rates of the produced litter before and after N addition were comparable among plots, even though the soil inorganic N fertility increased greatly. These results suggest that immediate response of Sasa to an increase of soil inorganic N mitigates the excess N leaching from soil.

  11. Improving health promotion through central rating of interventions: the need for Responsive Guidance.

    Science.gov (United States)

    Kok, Maarten Olivier; Bal, Roland; Roelofs, Caspar David; Schuit, Albertine Jantine

    2017-11-23

    In several countries, attempts are made to improve health promotion by centrally rating the effectiveness of health promotion interventions. The Dutch Effectiveness Rating System (ERS) for health promotion interventions is an improvement-oriented approach in which multi-disciplinary expert committees rate available health promotion interventions as 'theoretically sound', 'probably effective' or 'proven effective'. The aim of this study is to explore the functioning of the ERS and the perspective of researchers, policy-makers and practitioners regarding its contribution to improvement. We interviewed 53 selected key informants from research, policy and practice in the Netherlands and observed the assessment of 12 interventions. Between 2008 and 2012, a total of 94 interventions were submitted to the ERS, of which 23 were rejected, 58 were rated as 'theoretically sound', 10 were rated as 'probably effective' and 3 were rated as 'proven effective'. According to participants, the ERS was intended to facilitate both the improvement of available interventions and the improvement of health promotion in practice. While participants expected that describing and rating interventions promoted learning and enhanced the transferability of interventions, they were concerned that the ERS approach was not suitable for guiding intervention development and improving health promotion in practice. The expert committees that assessed the interventions struggled with a lack of norms for the relevance of effects and questions about how effects should be studied and rated. Health promotion practitioners were concerned that the ERS neglected the local adaptation of interventions and did not encourage the improvement of aspects like applicability and costs. Policy-makers and practitioners were worried that the lack of proven effectiveness legitimised cutbacks rather than learning and advancing health promotion. While measuring and centrally rating the effectiveness of interventions can be

  12. Measurement and Analysis of Olfactory Responses with the Aim of Establishing an Objective Diagnostic Method for Central Olfactory Disorders

    Science.gov (United States)

    Uno, Tominori; Wang, Li-Qun; Miwakeichi, Fumikazu; Tonoike, Mitsuo; Kaneda, Teruo

    In order to establish a new diagnostic method for central olfactory disorders and to identify objective indicators, we measured and analyzed brain activities in the parahippocampal gyrus and uncus, region of responsibility for central olfactory disorders. The relationship between olfactory stimulation and brain response at region of responsibility can be examined in terms of fitted responses (FR). FR in these regions may be individual indicators of changes in brain olfactory responses. In the present study, in order to non-invasively and objectively measure olfactory responses, an odor oddball task was conducted on four healthy volunteers using functional magnetic resonance imaging (fMRI) and a odorant stimulator with blast-method. The results showed favorable FR and activation in the parahippocampal gyrus or uncus in all subjects. In some subjects, both the parahippocampal gyrus and uncus were activated. Furthermore, activation was also confirmed in the cingulate gyrus, middle frontal gyrus, precentral gyrus, postcentral gyrus, superior temporal gyrus and insula. The hippocampus and uncus are known to be involved in the olfactory disorders associated with early-stage Alzheimer's disease and other olfactory disorders. In the future, it will be necessary to further develop the present measurement and analysis method to clarify the relationship between central olfactory disorders and brain activities and establish objective indicators that are useful for diagnosis.

  13. Response of foster grapefruit (Citrus paradisi Macf. to organic and inorganic fertilization in central Sudan

    Directory of Open Access Journals (Sweden)

    Abdalla A.M. Elhassan

    2011-06-01

    Full Text Available The response of Foster grapefruit (Citrus paradisi Macf. to organic and inorganic fertilization in Sennar area (13°37′N–33°37′E representing central Sudan, was studied for two successive seasons (2003/2004 and 2004/2005. Urea, sheep manure and terra-sorb (as foliar at the rates of 2.17 kg/tree/year, 20 kg/tree/year and 200 ml/100 L water, respectively, and their combinations were applied to 18 years old trees to determine their effects on fruit yield and quality. The layout was a randomized complete block design replicated three times. Results indicated that all treatments significantly increased average yield over control with inconsistent effects on fruit quality parameters. Trees received urea at the rate of 2.17 kg/tree/year, yielded thick peel fruits of reduced vitamin C. Sheep manure at the rate of 20 kg/tree/year resulted in dark green fruits of thick peel. The foliar treated trees at the rate of 200 ml/100 L water gave little thick peel fruits of lower total soluble solids, low % titrable acidity and low vitamin C. The best fruits reflected by color, thinner peel, high % TSS and high vitamin C were obtained from urea + sheep manure treatment. Application of urea with foliar gave green large fruits. Small fruits of intensive green color on surface and low titrable acidity were recorded by combination of sheep manure and foliar. Application of the three fertilizers together gave fruits of dark green color on surface and thick peel. Therefore, application of 2.17 kg urea + 20 kg sheep manure/tree/year is recommended to Foster grapefruit trees in Sennar area and areas of similar environmental conditions.

  14. Delineating hierarchy of selenotranscriptome expression and their response to selenium status in chicken central nervous system.

    Science.gov (United States)

    Jiang, Xiu-Qing; Cao, Chang-Yu; Li, Zhao-Yang; Li, Wei; Zhang, Cong; Lin, Jia; Li, Xue-Nan; Li, Jing-Long

    2017-04-01

    Selenium (Se) incorporated in selenoproteins as selenocysteine and supports various important cellular and organismal functions. We recently reported that chicken brain exhibited high priority for Se supply and retention under conditions of dietary Se deficiency and supernutrition Li et al. (2012) . However, the selenotranscriptome expressions and their response to Se status in chicken central nervous system (CNS) are unclear. To better understand the relationship of Se homeostasis and selenoproteins expression in chicken CNS, 1day-old HyLine White chickens were fed a low Se diet (Se-L, 0.028mg/g) supplemented with 4 levels of dietary Se (0 to 5.0mgSe/kg) as Na 2 SeO 3 for 8weeks. Then chickens were dissected for getting the CNS, which included cerebral cortex, cerebellum, thalamus, bulbus cinereus and marrow. The expressions of selenoproteome which have 24 selenoproteins were detected by the quantitative real-time PCR array. The concept of a selenoprotein hierarchy was developed and the hierarchy of different regions in chicken CNS was existence, especially cerebral cortex and bulbus cinereus. The expression of selenoproteins has a hierarch while changing Se content, and Selenoprotein T (Selt), Selenoprotein K (Selk), Selenoprotein W (Selw), Selenoprotein U (Selu), Glutathione peroxidase 3 (Gpx3), Glutathione peroxidase 4 (Gpx4), Selenoprotein P (Sepp1), Selenoprotein O (Selo), Selenoprotein 15 (Sel15), Selenoprotein N (Seln), Glutathione peroxidase 2 (Gpx2) and Selenoprotein P 2 (Sepp2) take more necessary function in the chicken CNS. Therefore, we hypothesize that hierarchy of regulated the transcriptions of selenoproteome makes an important role of CNS Se metabolism and transport in birds. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Maize Response to Fertilizer Dosing at Three Sites in the Central Rift Valley of Ethiopia

    Directory of Open Access Journals (Sweden)

    Getachew Sime

    2014-09-01

    Full Text Available This study examines the agronomic response, efficiency and profitability of fertilizer microdosing in maize. An experiment with the following treatments was conducted: control without fertilizer, microdosing treatments, with the rate of 27 + 27, 53 + 53 and 80 + 80 kg ha−1, and banding of fertilizer with 100 + 100 kg ha−1 of di ammonium phosphate (DAP + urea, applied at planting and jointing, respectively. The treatments were arranged in a randomized complete block design with four replications. The experiment was conducted during the 2011/2012 and 2012/2013 cropping seasons at Ziway, Melkassa and Hawassa in the semiarid central rift valley region of Ethiopia. Compared to the control, the fertilizer treatments had higher yield and fertilizer use efficiency (FUE profitably. The 27 + 27 kg ha−1 fertilizer rate increased the grain yield by 19, 45 and 46% at Hawassa, Ziway and Melkassa, respectively, and it was equivalent to the higher rates. The value cost ratio (VCR was highest with the lowest fertilizer rate, varying between seven and 11 in the treatment with 27 + 27 kg ha−1, but two and three in the banding treatment. Similarly, FUE was highest with the lowest fertilizer rate, varying between 23 and 34 kg kg−1 but 7 and 8 kg kg−1 in the banding treatment. The improved yield, FUE, VCR and gross margin in maize with microdosing at the 27 + 27 kg ha−1 of DAP + urea rate makes it low cost, low risk, high yielding and profitable. Therefore, application of this particular rate in maize may be an option for the marginal farmers in the region with similar socioeconomic and agroecological conditions.

  16. Allogeneic stem cell transplantation for adult patients with acute lymphoblastic leukemia who had central nervous system involvement: a study from the Adult ALL Working Group of the Japan Society for Hematopoietic Cell Transplantation.

    Science.gov (United States)

    Shigematsu, Akio; Kako, Shinichi; Mitsuhashi, Kenjiro; Iwato, Koji; Uchida, Naoyuki; Kanda, Yoshinobu; Fukuda, Takahiro; Sawa, Masashi; Senoo, Yasushi; Ogawa, Hiroyasu; Miyamura, Koichi; Takada, Satoru; Nagamura-Inoue, Tokiko; Morishima, Yasuo; Ichinohe, Tatsuo; Atsuta, Yoshiko; Mizuta, Shuichi; Tanaka, Junji

    2017-06-01

    The prognosis for adult acute lymphoblastic leukemia (ALL) patients with central nervous system (CNS) involvement (CNS+) who received allogeneic hematopoietic stem cell transplantation (allo-SCT) remains unclear. We retrospectively compared the outcomes of allo-SCT for patients with CNS involvement and for patients without CNS involvement (CNS-) using a database in Japan. The eligibility criteria for this study were as follows: diagnosis of ALL, aged more than 16 years, allo-SCT between 2005 and 2012, and first SCT. Data for 2582 patients including 136 CNS+ patients and 2446 CNS- patients were used for analyses. As compared with CNS- patients, CNS+ patients were younger, had worse disease status at SCT and had poorer performance status (PS) at SCT (P < 0.01). Incidence of relapse was higher in CNS+ patients (P = 0.02), and incidence of CNS relapse was also higher (P < 0.01). The probability of 3-year overall survival (OS) was better in CNS- patients (P < 0.01) by univariate analysis. However, in patients who received SCT in CR, there was no difference in the probability of OS between CNS+ and CNS- patients (P = 0.38) and CNS involvement did not have an unfavorable effect on OS by multivariate analysis. CNS+ patients who achieved CR showed OS comparable to that of CNS- patients.

  17. Application of UAV-SfM photogrammetry and aerial lidar to a disastrous flood: repeated topographic measurement of a newly formed crevasse splay of the Kinu River, central Japan

    Science.gov (United States)

    Izumida, Atsuto; Uchiyama, Shoichiro; Sugai, Toshihiko

    2017-09-01

    Geomorphic impacts of a disastrous crevasse splay that formed in September 2015 and its post-formation modifications were quantitatively documented by using repeated, high-definition digital surface models (DSMs) of an inhabited and cultivated floodplain of the Kinu River, central Japan. The DSMs were based on pre-flood (resolution: 2 m) and post-flood (resolution: 1 m) aerial light detection and ranging (lidar) data from January 2007 and September 2015, respectively, and on structure-from-motion (SfM) photogrammetry data (resolution: 3.84 cm) derived from aerial photos taken by an unmanned aerial vehicle (UAV) in December 2015. After elimination of systematic errors among the DSMs and down-sampling of the SfM-derived DSM, elevation changes on the order of 10-1 m - including not only topography but also growth of vegetation, vanishing of flood waters, and restoration and repair works - were detected. Comparison of the DSMs showed that the volume eroded by the flood was more than twice the deposited volume in the area within 300-500 m of the breached artificial levee, where the topography was significantly affected. The results suggest that DSMs based on a combination of UAV-SfM and lidar data can be used to quantify, rapidly and in rich detail, topographic changes on floodplains caused by floods.

  18. Hydrologic response in karstic-ridge wetlands to rainfall and evapotranspiration, central Florida, 2001-2003

    Science.gov (United States)

    Knowles, Leel; Phelps, G.G.; Kinnaman, Sandra L.; German, Edward R.

    2005-01-01

    Two internally drained karstic wetlands in central Florida-Boggy Marsh at the Hilochee Wildlife Management Area and a large unnamed wetland at the Lyonia Preserve-were studied during 2001-03 to gain a better understanding of the net-recharge function that these wetlands provide, the significance of exchanges with ground water with regard to wetland water budgets, and the variability in wetland hydrologic response to a range of climate conditions. These natural, relatively remote and unaltered wetlands were selected to provide a baseline of natural wetland hydrologic variability to which anthropogenic influences on wetland hydrology could be compared. Large departures from normal rainfall during the study were fortuitous, and allowed monitoring of hydrologic processes over a wide range of climate conditions. Wetland responses varied greatly as a result of climate conditions that ranged from moderate drought to extremely moist. Anthropogenic activities influenced water levels at both study sites; however, because these activities were brief relative to the duration of the study, sufficient data were collected during unimpacted periods to allow for the following conclusions to be made. Water budgets developed for Boggy Marsh and the Lyonia large wetland showed strong similarity between the flux terms of rainfall, evaporation, net change in storage, and the net ground-water exchange residual. Runoff was assumed to be negligible. Of the total annual flux at Boggy Marsh, rainfall accounted for 45 percent; evaporation accounted for 25 percent; net change in storage accounted for 25 percent; and the net residual accounted for 5 percent. At the Lyonia large wetland, rainfall accounted for 44 percent; evaporation accounted for 29 percent; net change in storage accounted for 21 percent; and the net residual accounted for 6 percent of the total annual flux. Wetland storage and ground-water exchange were important when compared to the total water budget at both wetlands. Even

  19. Human cold stress of strong local-wind "Hijikawa-arashi" in Japan, based on the UTCI index and thermo-physiological responses

    Science.gov (United States)

    Ohashi, Yukitaka; Katsuta, Takumi; Tani, Haruka; Okabayashi, Taiki; Miyahara, Satoshi; Miyashita, Ryoji

    2018-03-01

    We investigated the cold stress caused by a strong local wind called "Hijikawa-arashi," through in situ vital measurements and the Universal Thermal Climate Index (UTCI). This wind is a very interesting winter phenomenon, localized in an area within 1 km of the seashore in Ozu City, Ehime Prefecture in Japan. When a strong Hijikawa-arashi (HA) occurred at 14-15 m s-1, the UTCI decreased to - 30 °C along the bridge where commuting residents are the most exposed to strong and cold winds. On the bridge, most participants in our experiment felt "very cold" or "extremely cold." The UTCI of HA can be predicted from a multiple regression equation using wind speed and air temperature. The cold HA wind is also harmful to human thermo-physiological responses. It leads to higher blood pressure and increased heart rate, both of which act as cardiovascular stress triggers. Increases of 6-10 mmHg and 3-6 bpm for every 10 °C reduction in UTCI were seen on all observational days, including HA and non-HA days. In fact, the participants' body skin temperatures decreased by approximately 1.2 to 1.7 °C for every 10 °C reduction in UTCI. Thus, the UTCI variation due to the HA outbreak corresponded well with the cold sensation and thermo-physiological responses in humans. This result suggests that daily UTCI monitoring enables the prediction of thermo-physiological responses to the HA cold stress.

  20. Human cold stress of strong local-wind "Hijikawa-arashi" in Japan, based on the UTCI index and thermo-physiological responses.

    Science.gov (United States)

    Ohashi, Yukitaka; Katsuta, Takumi; Tani, Haruka; Okabayashi, Taiki; Miyahara, Satoshi; Miyashita, Ryoji

    2018-03-30

    We investigated the cold stress caused by a strong local wind called "Hijikawa-arashi," through in situ vital measurements and the Universal Thermal Climate Index (UTCI). This wind is a very interesting winter phenomenon, localized in an area within 1 km of the seashore in Ozu City, Ehime Prefecture in Japan. When a strong Hijikawa-arashi (HA) occurred at 14-15 m s -1 , the UTCI decreased to - 30 °C along the bridge where commuting residents are the most exposed to strong and cold winds. On the bridge, most participants in our experiment felt "very cold" or "extremely cold." The UTCI of HA can be predicted from a multiple regression equation using wind speed and air temperature. The cold HA wind is also harmful to human thermo-physiological responses. It leads to higher blood pressure and increased heart rate, both of which act as cardiovascular stress triggers. Increases of 6-10 mmHg and 3-6 bpm for every 10 °C reduction in UTCI were seen on all observational days, including HA and non-HA days. In fact, the participants' body skin temperatures decreased by approximately 1.2 to 1.7 °C for every 10 °C reduction in UTCI. Thus, the UTCI variation due to the HA outbreak corresponded well with the cold sensation and thermo-physiological responses in humans. This result suggests that daily UTCI monitoring enables the prediction of thermo-physiological responses to the HA cold stress.

  1. Epidemiological evaluation of cat health at a first-response animal shelter in Fukushima, following the Great East Japan Earthquakes of 2011.

    Science.gov (United States)

    Tanaka, Aki; Kass, Philip H; Martinez-Lopez, Beatriz; Hayama, Shinichi

    2017-01-01

    The Great East Japan Earthquakes of March 11, 2011 caused immense harm to the community and subsequent nuclear accident in Fukushima Prefecture extended the damage. Local residents were forced to evacuated without pets and the left behind animals were rescued from the restricted zone one month later. Unplanned animal rescue and unregulated sheltering caused secondary damage to animals such as disease epidemics at impounded animal shelter. The purpose of this study was to retrospectively evaluate the incidence of upper respiratory infection (URI) and diarrhea in cats at the first response animal shelter in Fukushima, and investigate factors affecting the duration of disease and determinants of treatments performed. Eighty percent and 59% of impounded cats developed URI, 71% and 54% of cats developed diarrhea, and 91% and 83% of cats had at least one disease in 2011 and 2012, respectively. Uses of multiple drug administration (more than five drugs) was associated with prolonged URI and diarrhea. Multiple antibiotics, antihistamines, interferon, and steroids were associated with relapse of and prolonged URI. Developing a standardized treatment protocol for commonly observed diseases at Japanese animal shelters to prevent and control diseases, to promote animal welfare, and protect public health in the face of future disasters is overdue.

  2. Thermal Responses of Growth and Toxin Production in Four Prorocentrum Species from the Central Red Sea

    KAUST Repository

    Aynousah, Arwa

    2017-01-01

    Prorocentrum strains isolated from the Central Red Sea, Saudi Arabia. Morphological and molecular phylogenetic analysis identified the strains as P. elegans, P. rhathymum and P. emarginatum. However, the identity of strain P. sp.6 is currently unresolved

  3. Redox front penetration in the fractured Toki Granite, central Japan: An analogue for redox reactions and redox buffering in fractured crystalline host rocks for repositories of long-lived radioactive waste

    International Nuclear Information System (INIS)

    Yamamoto, Koshi; Yoshida, Hidekazu; Akagawa, Fuminori; Nishimoto, Shoji; Metcalfe, Richard

    2013-01-01

    Highlights: • Deep redox front developed in orogenic granitic rock have been studied. • The process was controlled by the buffering capacity of minerals. • This is an analogue of redox front penetration into HLW repositories in Japan. - Abstract: Redox buffering is one important factor to be considered when assessing the barrier function of potential host rocks for a deep geological repository for long-lived radioactive waste. If such a repository is to be sited in fractured crystalline host rock it must be demonstrated that waste will be emplaced deeper than the maximum depth to which oxidizing waters can penetrate from the earth’s surface via fractures, during the assessment timeframe (typically 1 Ma). An analogue for penetration of such oxidizing water occurs in the Cretaceous Toki Granite of central Japan. Here, a deep redox front is developed along water-conducting fractures at a depth of 210 m below the ground surface. Detailed petrographical studies and geochemical analyses were carried out on drill core specimens of this redox front. The aim was to determine the buffering processes and behavior of major and minor elements, including rare earth elements (REEs), during redox front development. The results are compared with analytical data from an oxidized zone found along shallow fractures (up to 20 m from the surface) in the same granitic rock, in order to understand differences in elemental migration according to the depth below the ground surface of redox-front formation. Geochemical analyses by XRF and ICP-MS of the oxidized zone at 210 m depth reveal clear changes in Fe(III)/Fe(II) ratios and Ca depletion across the front, while Fe concentrations vary little. In contrast, the redox front identified along shallow fractures shows strong enrichments of Fe, Mn and trace elements in the oxidized zone compared with the fresh rock matrix. The difference can be ascribed to the changing Eh and pH of groundwater as it flows downwards in the granite, due to

  4. Competition in Japan

    OpenAIRE

    Michael E. Porter; Mariko Sakakibara

    2004-01-01

    This article examines competition in Japan and its link to postwar economic prosperity. While Japan's industrial structure and competition policy seem to indicate that competition in Japan has been less intense, the empirical evidence does not support this conclusion. The sectors in which competition was restricted prove to be those where Japan was not internationally successful. In the internationally successful sectors, internal competition in Japan was invariably fierce. While the level of...

  5. A Model of Electrically Stimulated Auditory Nerve Fiber Responses with Peripheral and Central Sites of Spike Generation

    DEFF Research Database (Denmark)

    Joshi, Suyash Narendra; Dau, Torsten; Epp, Bastian

    2017-01-01

    . A single ANF is modeled as a network of two exponential integrateand-fire point-neuron models, referred to as peripheral and central axons of the ANF. The peripheral axon is excited by the cathodic charge, inhibited by the anodic charge, and exhibits longer spike latencies than the central axon......A computational model of cat auditory nerve fiber (ANF) responses to electrical stimulation is presented. The model assumes that (1) there exist at least two sites of spike generation along the ANF and (2) both an anodic (positive) and a cathodic (negative) charge in isolation can evoke a spike......; the central axon is excited by the anodic charge, inhibited by the cathodic charge, and exhibits shorter spike latencies than the peripheral axon. The model also includes subthreshold and suprathreshold adaptive feedback loops which continuously modify the membrane potential and can account for effects...

  6. Time constraints for post-LGM landscape response to deglaciation in Val Viola, Central Italian Alps

    Science.gov (United States)

    Scotti, Riccardo; Brardinoni, Francesco; Crosta, Giovanni Battista; Cola, Giuseppe; Mair, Volkmar

    2017-12-01

    Across the northern European Alps, a long tradition of Quaternary studies has constrained post-LGM (Last Glacial Maximum) landscape history. The same picture remains largely unknown for the southern portion of the orogen. In this work, starting from existing 10Be exposure dating of three boulders in Val Viola, Central Italian Alps, we present the first detailed, post-LGM reconstruction of landscape (i.e., glacial, periglacial and paraglacial) response south of the Alpine divide. We pursue this task through Schmidt-hammer exposure-age dating (SHD) at 34 sites including moraines, rock glaciers, protalus ramparts, rock avalanche deposits and talus cones. In addition, based on the mapping of preserved moraines and on the numerical SHD ages, we reconstruct the glacier extent of four different stadials, including Egesen I (13.1 ± 1.1 ka), Egesen II (12.3 ± 0.6 ka), Kartell (11.0 ± 1.4 ka) and Kromer (9.7 ± 1.4 ka), whose chronologies agree with available counterparts from north of the Alpine divide. Results show that Equilibrium Line Altitude depressions (ΔELAs) associated to Younger Dryas and Early Holocene stadials are smaller than documented at most available sites in the northern Alps. These findings not only support the hypothesis of a dominant north westerly atmospheric circulation during the Younger Dryas, but also suggest that this pattern could have lasted until the Early Holocene. SHD ages on rock glaciers and protalus ramparts indicate that favourable conditions to periglacial landform development occurred during the Younger Dryas (12.7 ± 1.1 ka), on the valley slopes above the glacier, as well as in newly de-glaciated areas, during the Early Holocene (10.7 ± 1.3 and 8.8 ± 1.8 ka). The currently active rock glacier started to develop before 3.7 ± 0.8 ka and can be associated to the Löbben oscillation. Four of the five rock avalanches dated in Val Viola cluster within the Early Holocene, in correspondence of an atmospheric warming phase. By contrast

  7. Compartmentalization of innate immune responses in the central nervous system during cryptococcal meningitis/HIV coinfection.

    Science.gov (United States)

    Naranbhai, Vivek; Chang, Christina C; Durgiah, Raveshni; Omarjee, Saleha; Lim, Andrew; Moosa, Mahomed-Yunus S; Elliot, Julian H; Ndung'u, Thumbi; Lewin, Sharon R; French, Martyn A; Carr, William H

    2014-03-13

    The role of innate immunity in the pathogenesis of cryptococcal meningitis is unclear. We hypothesized that natural killer (NK) cell and monocyte responses show central nervous system (CNS) compartment-specific profiles, and are altered by antifungal therapy and combination antiretroviral therapy (cART) during cryptococcal meningitis/HIV coinfection. Substudy of a prospective cohort study of adults with cryptococcal meningitis/HIV coinfection in Durban, South Africa. We used multiparametric flow cytometry to study compartmentalization of subsets, CD69 (a marker of activation), CXCR3 and CX3CR1 expression, and cytokine secretion of NK cells and monocytes in freshly collected blood and cerebrospinal fluid (CSF) at diagnosis (n = 23), completion of antifungal therapy induction (n = 19), and after a further 4 weeks of cART (n = 9). Relative to blood, CSF was enriched with CD56(bright) (immunoregulatory) NK cells (P = 0.0004). At enrolment, CXCR3 expression was more frequent among blood CD56(bright) than either blood CD56(dim) (P pos) NK-cell proportions nor CX3CR1(pos) NK-cell proportions. CD56(bright) and CD56(dim) NK cells were more activated in CSF than blood (P < 0.0001). Antifungal therapy induction reduced CD56(dim) NK-cell activation in CSF (P = 0.02). Activation of blood CD56(bright) and CD56(dim) NK cells was diminished following cART commencement (P < 0.0001, P = 0.03). Immunoregulatory NK cells in CSF tended to secrete higher levels of CXCL10 (P = 0.06) and lower levels of tumor necrosis factor α (P = 0.06) than blood immunoregulatory NK cells. CSF was enriched with nonclassical monocytes (P = 0.001), but antifungal therapy restored proportions of classical monocytes (P = 0.007). These results highlight CNS activation, trafficking, and function of NK cells and monocytes in cryptococcal meningitis/HIV and implicate immunoregulatory NK cells and proinflammatory monocytes as potential modulators of cryptococcal meningitis pathogenesis during HIV coinfection.

  8. OECD validation of the Hershberger assay in Japan: phase 2 dose response of methyltestosterone, vinclozolin, and p,p'-DDE.

    Science.gov (United States)

    Yamasaki, Kanji; Sawaki, Masakuni; Ohta, Ryo; Okuda, Hirokazu; Katayama, Seiichi; Yamada, Tomoya; Ohta, Takafumi; Kosaka, Tadashi; Owens, William

    2003-01-01

    The Organisation for Economic Co-operation and Development has initiated the development of new guidelines for the screening and testing of potential endocrine disruptors. The Hershberger assay is one of the assays selected for validation based on the need for in vivo screening to detect androgen agonists or antagonists by measuring the response of five sex accessory organs and tissues of castrated juvenile male rats: the ventral prostate, the seminal vesicles with coagulating glands, the levator ani and bulbocavernosus muscle complex, the Cowper's glands, and the glans penis. The phase 1 feasibility demonstration stage of the Hershberger validation program has been successfully completed with a single androgen agonist and a single antagonist as reference substances. The phase 2 validation program employs a range of additional androgen agonists and antagonists as well as 5alpha-reductase inhibitors. Seven Japanese laboratories have contributed phase 2 validation studies of the Hershberger assay using methyltestosterone, vinclozolin, and 2,2-bis (4-chlorophenyl)-1,1-dichloroethylene (p,p'-DDE). The methyltestosterone doses were 0, 0.05, 0.5, 5, and 50 mg/kg/day, and the vinclozolin and p,p'-DDE doses were 0, 3, 10, 30, and 100 mg/kg/day. All chemicals were orally administered by gavage for 10 consecutive days. In the antagonist version of the assay using vinclozolin and p,p'-DDE, 0.2 mg/kg/day of testosterone propionate was coadministered by subcutaneous injection. All five accessory sex preproductive organs and tissues consistently responded with statistically significant changes in weight within a narrow window. Therefore, the Japanese studies support the Hershberger assay as a reliable and reproducible screening assay for the detection of androgen agonistic and antagonistic effects. PMID:14644666

  9. Moral Education in Japan

    DEFF Research Database (Denmark)

    Roesgaard, Marie Højlund

    ‘religion’ is not a subject in schools. So, how do the Japanese go about the business of teaching values and morality? Using the Japanese example, this volume looks at moral education from the basic point of view of universal and common human values, with due attention given to culture-specific traits...... in the legal frame work (the Fundamental Law on Education was revised in 2006) and the ministerial guidelines and policies (new curriculum guidelines have been issued after the law change, and new proposals for strengthening the position of moral education come on a regular basis) have reflected the increased......What is a ‘good’ person and how do we educate ‘good’ persons? This question of morality is central to any society and its government and educational system including the Japanese. In many societies it has been customary to teach about morality from a religious standpoint, but not so in Japan, where...

  10. Actual measurement, hygrothermal response experiment and growth prediction analysis of microbial contamination of central air conditioning system in Dalian, China.

    Science.gov (United States)

    Lv, Yang; Hu, Guangyao; Wang, Chunyang; Yuan, Wenjie; Wei, Shanshan; Gao, Jiaoqi; Wang, Boyuan; Song, Fangchao

    2017-04-03

    The microbial contamination of central air conditioning system is one of the important factors that affect the indoor air quality. Actual measurement and analysis were carried out on microbial contamination in central air conditioning system at a venue in Dalian, China. Illumina miseq method was used and three fungal samples of two units were analysed by high throughput sequencing. Results showed that the predominant fungus in air conditioning unit A and B were Candida spp. and Cladosporium spp., and two fungus were further used in the hygrothermal response experiment. Based on the data of Cladosporium in hygrothermal response experiment, this paper used the logistic equation and the Gompertz equation to fit the growth predictive model of Cladosporium genera in different temperature and relative humidity conditions, and the square root model was fitted based on the two environmental factors. In addition, the models were carried on the analysis to verify the accuracy and feasibility of the established model equation.

  11. The prefrontal oxygenation and ventilatory responses at start of one-legged cycling exercise have relation to central command.

    Science.gov (United States)

    Asahara, Ryota; Matsukawa, Kanji; Ishii, Kei; Liang, Nan; Endo, Kana

    2016-11-01

    When performing exercise arbitrarily, activation of central command should start before the onset of exercise, but when exercise is forced to start with cue, activation of central command should be delayed. We examined whether the in-advance activation of central command influenced the ventilatory response and reflected in the prefrontal oxygenation, by comparing the responses during exercise with arbitrary and cued start. The breath-by-breath respiratory variables and the prefrontal oxygenated-hemoglobin concentration (Oxy-Hb) were measured during one-legged cycling. Minute ventilation (V̇e) at the onset of arbitrary one-legged cycling was augmented to a greater extent than cued cycling, while end-tidal carbon dioxide tension (ETco 2 ) decreased irrespective of arbitrary or cued start. Symmetric increase in the bilateral prefrontal Oxy-Hb occurred before and at the onset of arbitrary one-legged cycling, whereas such an increase was absent with cued start. The time course and magnitude of the increased prefrontal oxygenation were not influenced by the extent of subjective rating of perceived exertion and were the same as those of the prefrontal oxygenation during two-legged cycling previously reported. Mental imagery or passive performance of the one-legged cycling increased V̇e and decreased ETco 2 Neither intervention, however, augmented the prefrontal Oxy-Hb. The changes in ETco 2 could not explain the prefrontal oxygenation response during voluntary or passive one-legged cycling. Taken together, it is likely that the in-advance activation of central command influenced the ventilatory response by enhancing minute ventilation at the onset of one-legged cycling exercise and reflected in the preexercise increase in the prefrontal oxygenation. Copyright © 2016 the American Physiological Society.

  12. Zircon growth in a granitic pluton with specific mechanisms, crystallization temperatures and U-Pb ages. Implication to the 'spatiotemporal' formation process of the Toki granite, central Japan

    International Nuclear Information System (INIS)

    Yuguchi, Takashi; Ishibashi, Masayuki; Sasao, Eiji; Iwano, Hideki; Danhara, Tohru; Kato, Takenori; Sakata, Shuhei; Hattori, Kentaro; Hirata, Takafumi; Sueoka, Shigeru; Nishiyama, Tadao

    2016-01-01

    Zircons collected from a granitic pluton provide evidence of serial growth events with specific mechanisms, crystallization temperatures and U-Pb ages, revealing details of the sequential formation process from intrusion through emplacement to crystallization/solidification. The events have been identified by: 1) the study of the internal structure of zircon using cathodoluminescence, 2) deriving crystallization temperatures using Ti-in-zircon thermometry of the internal structure and 3) U-Pb age dating of the internal structure. The magmatic zircons from the Toki granite, central Japan, show two kinds in their internal structure: a low luminescence core (LLC) and oscillatory zonation (OZ). The LLC was produced by interfacial reaction-controlled growth in the granitic magma with cooling from about 910 to 760°C. The formation of OZ occurred by diffusion-controlled growth in a cooling magma chamber from about 850 to 690°C. The U-Pb ages derived from the LLC ranges from 74.7 ± 4.2 to 70.5 ± 1.3 Ma, indicating the incipient intrusion timing of the magma into the shallow crust. The OZ ages distribute from 72.7 ± 0.6 to 70.4 ± 1.7 Ma, which mean the timing from emplacement to crystallization/solidification of the granite pluton. Thus, the serial processes from intrusion through emplacement to crystallization/solidification occurred within a few million years. The old LLC and OZ ages are recognized in the western margins of the Toki granite, implying that the magma forming the western margins was the first to intrude, emplace and crystallize/solidify. The western margins with initial intrusion may accompany the crustal assimilation in order to create sufficient magma reservoir space, which is consistent with larger SrI and ASI values found in the western margins of the granite. (author)

  13. ARAC: a centralized computer-assisted emergency planning, response, and assessment system for atmospheric releases of toxic material

    International Nuclear Information System (INIS)

    Dickerson, M.H.; Knox, J.B.

    1987-01-01

    The Atmospheric Release Advisory Capability (ARAC) is an emergency planning, response, and assessment service, developed by the US Departments of Energy and Defense, and focused, thus far, on atmospheric releases of nuclear material. For the past 14 years ARAC has responded to over 150 accidents, potential accidents, and major exercises. The most notable accident responses are the COSMOS 954 reentry, the Three Mile Island (TMI-2) accident and subsequent purge of 85 Kr from the containment vessel, the recent UF 6 accident at the Kerr-McGee Plant, Gore, Oklahoma, and the Chernobyl nuclear reactor accident in the Soviet Union. Based on experience in the area of emergency response, developed during the past 14 years, this paper describes the cost effectiveness and other advantages of a centralized emergency planning, response, and assessment service for atmospheric releases of nuclear material

  14. ARAC: a centralized computer assisted emergency planning, response, and assessment system for atmospheric releases of toxic material

    International Nuclear Information System (INIS)

    Dickerson, M.H.; Knox, J.B.

    1986-10-01

    The Atmospheric Release Advisory Capability (ARAC) is an emergency planning, response, and assessment service, developed by the US Departments of Energy and Defense, and focused, thus far, on atmospheric releases of nuclear material. For the past 14 years ARAC has responded to over 150 accidents, potential accidents, and major exercises. The most notable accident responses are the COSMOS 954 reentry, the Three Mile Island (TMI-2) accident and subsequent purge of 85 Kr from the containment vessel, the recent UF 6 accident at the Kerr-McGee Plant, Gore, Oklahoma, and the Chernobyl nuclear reactor accident in the Soviet Union. Based on experience in the area of emergency response, developed during the past 14 years, this paper describes the cost effectiveness and other advantages of a centralized emergency planning, response, and assessment service for atmospheric releases of nuclear material

  15. Improving health promotion through central rating of interventions: the need for Responsive Guidance.

    NARCIS (Netherlands)

    Kok, Maarten Olivier; Bal, Roland; Roelofs, Caspar David; Schuit, Albertine Jantine

    2017-01-01

    In several countries, attempts are made to improve health promotion by centrally rating the effectiveness of health promotion interventions. The Dutch Effectiveness Rating System (ERS) for health promotion interventions is an improvement-oriented approach in which multi-disciplinary expert

  16. Behavioral responses of gorillas to habituation in the Dzanga-Ndoki National Park, Central African Republic

    NARCIS (Netherlands)

    Blom, A.; Cipolletta, C.; Brunsting, A.M.H.; Prins, H.H.T.

    2004-01-01

    We monitored the impact of habituation for tourism through changes in gorillas' behavior during the habituation process at Bai Hokou (Dzanga-Ndoki National Park, Central African Republic) from August 1996 to December 1999. From August 1998 onwards we focused on one gorilla group: the Munye. During

  17. Ponderosa pine growth response to soil strength in the volcanic ash soils of central Oregon.

    Science.gov (United States)

    R.T. Parker; D.A. Maguire; D.D. Marshall; P. Cochran

    2007-01-01

    Mechanical harvesting and associated logging activities have the capacity to compact soil across large portions of harvest units. Two thinning treatments (felled only versus felled and skidded) in 70- to 80-year-old ponderosa pine stands were replicated at three sites with volcanic soils in central Oregon. Growth in diameter, height, and volume of residual trees were...

  18. Central Cardiovascular Responses of Quadriplegic Subjects to Arm Exercise at Varying Levels of Oxygen Uptake.

    Science.gov (United States)

    Figoni, Stephen F.

    The purpose of this study was to assess selected central cardiovascular functions of spinal cord injured, quadriplegic subjects at varying levels of oxygen uptake (VO sub 2). Subjects included 11 untrained, male college students with C5, C6, or C7 complete quadriplegia and 11 able-bodied reference subjects. Exercise was performed on a Monark cycle…

  19. Japan Tobacco International: To 'be the most successful and respected tobacco company in the world'.

    Science.gov (United States)

    MacKenzie, Ross; Eckhardt, Jappe; Widyati Prastyani, Ade

    2017-03-01

    Japan Tobacco International (JTI) is the international division of Japan Tobacco Incorporated, and the world's third largest transnational tobacco company. Founded in 1999, JTI's rapid growth has been the result of a global business strategy that potentially serves as a model for other Asian tobacco companies. This paper analyses Japan Tobacco Incorporated's global expansion since the 1980s in response to market opening, foreign competition, and declining share of a contracting domestic market. Key features of its global strategy include the on-going central role and investment by the Japanese government, and an expansion agenda based on mergers and acquisitions. The paper also discusses the challenges this global business strategy poses for global tobacco control and public health. This paper is part of the special issue 'The Emergence of Asian Tobacco Companies: Implications for Global Health Governance'.

  20. The graying of Japan.

    Science.gov (United States)

    Martin, L G

    1989-07-01

    Japan's rapidly aging population has become a top policy issue, especially as the increasing costs of pensions and medical care are debated. With the highest life expectancy on earth, the Japanese potentially face long periods of retirement, as well as the possibility of long periods of disability. Although family support of the elderly is thought to have been strong traditionally, the recent decline in co-residence with children is 1 indication that the way support is given may be changing. This issue is of particular concern to the government, which wants to avoid any greater responsibility for the elderly than is necessary given the dramatic population aging yet to come. The government is also encouraging employers to provide more employment opportunities for the elderly at the same time that it is trying to raise the eligibility age for the receipt of public pensions. There is resistance on the part of employers, however, because wages and retirement allowances in Japan are positively related to length of employment. Furthermore, it is not clear whether elderly Japanese of the future will be as willing to work, if they learn to enjoy increased leisure early in their careers. Nevertheless, it is unlikely that population aging will lead to Japan's economic decline. Although the savings rate may decline somewhat, restructuring of the economy and continued overseas investment should keep the economy growing in the long run. Important in both the care of the frail elderly and the continued growth of the economy will be the roles played by middle-aged Japanese women.

  1. Influence of sex and age on febrile responses to peripheral and central administration of pyrogens in the rabbit.

    Science.gov (United States)

    Lipton, J M; Ticknor, C B

    1979-10-01

    1. Intravenous injections of leucocytic pyrogen in doses of 15, 30 and 60 mul./kg caused febrile reactions in male rabbits that were related to age of the animal: rabbits under 2 yr of age developed fevers that were related to dose of pyrogen, while rabbits 2-3 yr old showed large febrile responses which were not dose-related.2. Female rabbits of comparable ages generally showed smaller febrile reactions to I.V. leucocytic pyrogen, and still older females (3-5 yr) developed fever only after the largest dose.3. Dose-related febrile responses to 2.5, 5 and 10 mul. leucocytic pyrogen given intracerebroventricularly (I.C.V.) were greater in male rabbits 1-3 yr old than in females of comparable age. Female rabbits 3-5 yr old showed dose-related fevers that were smaller than those of younger animals of both sexes.4. There were no major differences in response to 125, 250 and 500 ng PGE(2), given I.C.V., between male and female rabbits under 2 yr of age. Females 2-3 yr of age had greater responses to PGE(2) than males of comparable age whilst the oldest females showed smaller responses.5. It is concluded that the febrile response of the rabbit to peripheral and central leucocytic pyrogen varies with both age and sex. Differences in sensitivity of central fever controls to endogenous pyrogen in animals of different ages and sexes may account for the different responses to peripheral pyrogen.

  2. Survey of innate immune responses to Burkholderia pseudomallei in human blood identifies a central role for lipopolysaccharide.

    Directory of Open Access Journals (Sweden)

    Narisara Chantratita

    . pseudomallei lipopolysaccharide in blood is greater than the response to other lipopolysaccharide expressing isolates. Our findings suggest that B. pseudomallei lipopolysaccharide may play a central role in stimulating the host response in melioidosis.

  3. Genetic response to metabolic fluctuations: correlation between central carbon metabolism and DNA replication in Escherichia coli

    Directory of Open Access Journals (Sweden)

    Szalewska-Pałasz Agnieszka

    2011-03-01

    Full Text Available Abstract Background Until now, the direct link between central carbon metabolism and DNA replication has been demonstrated only in Bacillus. subtilis. Therefore, we asked if this is a specific phenomenon, characteristic for this bacterium and perhaps for its close relatives, or a more general biological rule. Results We found that temperature-sensitivity of mutants in particular genes coding for replication proteins could be suppressed by deletions of certain genes coding for enzymes of the central carbon metabolism. Namely, the effects of dnaA46(ts mutation could be suppressed by dysfunction of pta or ackA, effects of dnaB(ts by dysfunction of pgi or pta, effects of dnaE486(ts by dysfunction of tktB, effects of dnaG(ts by dysfunction of gpmA, pta or ackA, and effects of dnaN159(ts by dysfunction of pta or ackA. The observed suppression effects were not caused by a decrease in bacterial growth rate. Conclusions The genetic correlation exists between central carbon metabolism and DNA replication in the model Gram-negative bacterium, E. coli. This link exists at the steps of initiation and elongation of DNA replication, indicating the important global correlation between metabolic status of the cell and the events leading to cell reproduction.

  4. Nuclear energy in Japan

    International Nuclear Information System (INIS)

    Guillemard, B.

    1978-01-01

    After having described the nuclear partners in Japan, the author analyzes the main aspects of Japan's nuclear energy: nuclear power plants construction program; developping of light water reactors; fuel cycle politics [fr

  5. Characteristics of Wet Deposition in Japan

    Science.gov (United States)

    Iwasaki, A.; Arakaki, T.

    2017-12-01

    Acid deposition survey in Japan has started since 1991 by Japan Environmental Laboratories Association (JELA). The JELA has about 60 monitoring sites for wet deposition including remote, rural and urban area. The measured constituents of wet deposition are; precipitation, pH, electric conductivity, major Anions, and major Cations. From those data, we analyze spatial and temporal variations of wet deposition components in Japan. Among the 60 monitoring sites, 39 sampling sites were selected in this study, which have kept sampling continuously between 2003JFY and 2014JFY. All samples were collected by wet-only samplers. To analyze area characteristics, all the areas were divided into 6 regions; Northern part of Japan (NJ), Facing the Japan Sea (JS), Eastern part of Japan (EJ), Central part of Japan (CJ), Western part of Japan (WJ) and Southern West Islands (SW). NO3- and non-sea-salt-SO42- (nss-SO42-) are major components of rain acidification. Especially, between December and February (winter) the air mass from west affected the temporal variations of those acid components and the concentrations were higher in JS and WJ regions than those in other regions. Japanese ministry of the Environment reported that mixing ratio of NO2 in Japan has been less than 0.04ppm since 1976, and that of SO2 has been less than 0.02ppm since 1978. Their concentrations in Japan have remained flat or slowly decreased recently. However the temporal variations of NO3-/nss-SO42- ratio in winter in JS region were significantly increased on average at 2.2% y-1 from 2003JFY to 2014JFY. The results suggest that long-range transboundary air pollutants increased NO3- concentrations and NO3-/nss-SO42- ratio.

  6. Restored agricultural wetlands in Central Iowa: habitat quality and amphibian response

    Science.gov (United States)

    Reeves, Rebecca A.; Pierce, Clay; Smalling, Kelly L.; Klaver, Robert W.; Vandever, Mark W.; Battaglin, William A.; Muths, Erin L.

    2016-01-01

    Amphibians are declining throughout the United States and worldwide due, partly, to habitat loss. Conservation practices on the landscape restore wetlands to denitrify tile drainage effluent and restore ecosystem services. Understanding how water quality, hydroperiod, predation, and disease affect amphibians in restored wetlands is central to maintaining healthy amphibian populations in the region. We examined the quality of amphibian habitat in restored wetlands relative to reference wetlands by comparing species richness, developmental stress, and adult leopard frog (Lithobates pipiens) survival probabilities to a suite of environmental metrics. Although measured habitat variables differed between restored and reference wetlands, differences appeared to have sub-lethal rather than lethal effects on resident amphibian populations. There were few differences in amphibian species richness and no difference in estimated survival probabilities between wetland types. Restored wetlands had more nitrate and alkaline pH, longer hydroperiods, and were deeper, whereas reference wetlands had more amphibian chytrid fungus zoospores in water samples and resident amphibians exhibited increased developmental stress. Restored and reference wetlands are both important components of the landscape in central Iowa and maintaining a complex of fish-free wetlands with a variety of hydroperiods will likely contribute to the persistence of amphibians in this landscape.

  7. Regionalization of municipal solid waste management in Japan: balancing the proximity principle with economic efficiency.

    Science.gov (United States)

    Okuda, Itaru; Thomson, Vivian E

    2007-07-01

    The proximity principle - disposing of waste close to its origin - has been a central value in municipal solid waste (MSW) management in Japan for the last 30 years and its widespread adoption has helped resolve numerous "Not in My Backyard" issues related to MSW management. However, MSW management costs have soared, in large part because of aggressive recycling efforts and because most MSW is incinerated in a country that has scarce landfill capacity. In addition, smaller, less sophisticated incinerators have been closed because of high dioxin emissions. Rising costs combined with the closure of smaller incinerators have shifted MSW management policy toward regionalization, which is the sharing of waste management facilities across municipalities. Despite the increased use of regionalized MSW facilities, the proximity principle remains the central value in Japanese MSW management. Municipal solid waste management has become increasingly regionalized in the United States, too, but different driving forces are at work in these two countries. The transition to regionalized MSW management in Japan results from strong governmental control at all levels, with the central government providing funds and policy direction and prefectures and municipalities being the primary implementing authorities. By contrast, market forces are a much stronger force with US MSW management, where local governments - with state government oversight - have primary responsibility for MSW management. We describe recent changes in Japan's MSW programs. We examine the connections between MSW facility regionalization, on the one hand, and, on the other hand, the proximity principle, coordination among local governments, central government control, and financing mechanisms.

  8. Rare earth element and strontium isotopic study of seamount-type limestones in Mesozoic accretionary complex of Southern Chichibu Terrane, central Japan. Implication for incorporation process of seawater REE into limestones

    International Nuclear Information System (INIS)

    Tanaka, Kazuya; Miura, Noriko; Asahara, Yoshihiro; Kawabe, Iwao

    2003-01-01

    Ishimaki and Tahara limestones occur as exotic blocks juxtaposed in the Mesozoic (Jurassic) accretionary complex of Southern Chichibu Terrane in eastern Aichi Prefecture, central Japan. They are supposed to be of the seamount-type limestone, since they have no terrigenous materials and are intimately associated with greenstones. REE (rare earth elements) and Sr isotopic studies for the limestones have been made in order to know their geochemical characteristics, ages and origins. Their 87 Sr/ 86 Sr ratios, when referred to the seawater 87 Sr/ 86 Sr curve and relevant geological data, suggest that Ishimaki and Tahara limestones are the late Permian and the Carboniferous to the Early Permian, respectively. Two greenstone fragments found inside the Ishimaki limestone block and one greenstone sample associated with Tahara limestone block, resemble the Hawaiian alkali basalt in the their REE and Y patterns. This is supporting the idea that the limestone blocks may be parts of reef limestones on ancient volcanic seamounts. All the limestone samples, except three unusual Tahara ones, show seawater REE and Y signatures in their chondrite-normalized patterns. Their REE/Ca ratios, however, are 10 2 -10 4 times as high as those ratios of modern biogenic carbonates like corals and the seawater. Accordingly, seawater REE and Y were incorporated into the limestones, when originally biogenic carbonates transformed into inorganic calcite and its secondary growths occurred in diagenesis in contact with sufficient seawater. This view is favored by the reported REE partition experiment between calcite overgrowths and seawater solution. The seawater Ce anomaly as a function of water depth in the modern ocean is a key to infer the water depth of the REE and Y incorporation. The Ce anomalies given by log (Ce/Ce*) for about a half of Ishimaki samples and most of Tahara ones are between -0.5 and -0.2, which are compatible with the shallow water origin. Another half of Ishimaki samples

  9. Response of the Land-Atmosphere System Over North-Central Oklahoma During the 2017 Eclipse

    Science.gov (United States)

    Turner, D. D.; Wulfmeyer, V.; Behrendt, A.; Bonin, T. A.; Choukulkar, A.; Newsom, R. K.; Brewer, W. A.; Cook, D. R.

    2018-02-01

    On 21 August 2017, a solar eclipse occurred over the continental United States resulting in a rapid reduction and subsequent increase of solar radiation over a large region of the country. The eclipse's effect on the land-atmosphere system is documented in unprecedented detail using a unique array of sensors deployed at three sites in north-central Oklahoma. The observations showed that turbulent fluxes of heat and momentum at the surface responded quickly to the change in solar radiation. The decrease in the sensible heat flux resulted in a decrease in the air temperature below 200 m, and a large decrease in turbulent motions throughout the boundary layer. Furthermore, the turbulent mixing in the boundary layer lagged behind the change in the surface fluxes, and this lag depended on the height above the surface. The turbulent motions increased and the convective boundary layer was reestablished as the sensible heat flux recovered.

  10. Peripheral dendritic cells are essential for both the innate and adaptive antiviral immune responses in the central nervous system

    International Nuclear Information System (INIS)

    Steel, Christina D.; Hahto, Suzanne M.; Ciavarra, Richard P.

    2009-01-01

    Intranasal application of vesicular stomatitis virus (VSV) causes acute infection of the central nervous system (CNS). However, VSV encephalitis is not invariably fatal, suggesting that the CNS may contain a professional antigen-presenting cell (APC) capable of inducing or propagating a protective antiviral immune response. To examine this possibility, we first characterized the cellular elements that infiltrate the brain as well as the activation status of resident microglia in the brains of normal and transgenic mice acutely ablated of peripheral dendritic cells (DCs) in vivo. VSV encephalitis was characterized by a pronounced infiltrate of myeloid cells (CD45 high CD11b + ) and CD8 + T cells containing a subset that was specific for the immunodominant VSV nuclear protein epitope. This T cell response correlated temporally with a rapid and sustained upregulation of MHC class I expression on microglia, whereas class II expression was markedly delayed. Ablation of peripheral DCs profoundly inhibited the inflammatory response as well as infiltration of virus-specific CD8 + T cells. Unexpectedly, the VSV-induced interferon-gamma (IFN-γ) response in the CNS remained intact in DC-deficient mice. Thus, both the inflammatory and certain components of the adaptive primary antiviral immune response in the CNS are dependent on peripheral DCs in vivo.

  11. Injury-Induced Type I IFN Signaling Regulates Inflammatory Responses in the Central Nervous System

    DEFF Research Database (Denmark)

    Khorooshi, Reza; Owens, Trevor

    2010-01-01

    Innate glial response is critical for the induction of inflammatory mediators and recruitment of leukocytes to sites of the injury in the CNS. We have examined the involvement of type I IFN signaling in the mouse hippocampus following sterile injury (transection of entorhinal afferents). Type I I...

  12. Neutrophils that infiltrate the central nervous system regulate T cell responses

    DEFF Research Database (Denmark)

    Zehntner, Simone P; Brickman, Cristina; Bourbonnière, Lyne

    2005-01-01

    Regulation of inflammatory responses is critical to progression of organ-specific autoimmune disease. Although many candidate cell types have been identified, immunoregulatory activity has rarely been directly assayed and never from the CNS. We have analyzed the regulatory capability of Gr-1high ...

  13. The new standard of fluids for hemodialysis in Japan.

    Science.gov (United States)

    Kawanishi, Hideki; Masakane, Ikuto; Tomo, Tadashi

    2009-01-01

    The standard of fluids for hemodialysis is being evaluated by the International Organization for Standardization (ISO), and will be decided within a few years. In 2008, the Japanese Society for Dialysis Therapy (JSDT) proposed the standard of fluids for hemodialysis by taking the draft ISO standard into consideration and the circumstances in Japan. It was characteristically a standard for Japan, where the central dialysis fluid delivery system (CDDS) is routinely used. In addition, the therapeutic application of each dialysis fluid is clarified. Since high-performance dialyzers are frequently employed in Japan, the standard recommends that ultrapure dialysis fluid be used for all dialysis modalities at all dialysis facilities. It also recommends that the dialysis equipment safety management committee at each facility validate the microbiological qualities of online-prepared substitution fluid, making the responsibility of the dialysis facility clear. This standard is more rigid than those of other countries, and is expected to contribute to improvements in the survival outcome of dialysis patients. (c) 2009 S. Karger AG, Basel.

  14. The CRF Family of Neuropeptides and their Receptors - Mediators of the Central Stress Response

    Science.gov (United States)

    Dedic, Nina; Chen, Alon; Deussing, Jan M.

    2018-01-01

    Background: Dysregulated stress neurocircuits, caused by genetic and/or environmental changes, underlie the development of many neuropsychiatric disorders. Corticotropin-releasing factor (CRF) is the major physiological activator of the hypothalamic-pituitary-adrenal (HPA) axis and conse-quently a primary regulator of the mammalian stress response. Together with its three family members, urocortins (UCNs) 1, 2, and 3, CRF integrates the neuroendocrine, autonomic, metabolic and behavioral responses to stress by activating its cognate receptors CRFR1 and CRFR2. Objective: Here we review the past and current state of the CRF/CRFR field, ranging from pharmacologi-cal studies to genetic mouse models and virus-mediated manipulations. Results: Although it is well established that CRF/CRFR1 signaling mediates aversive responses, includ-ing anxiety and depression-like behaviors, a number of recent studies have challenged this viewpoint by revealing anxiolytic and appetitive properties of specific CRF/CRFR1 circuits. In contrast, the UCN/CRFR2 system is less well understood and may possibly also exert divergent functions on physiol-ogy and behavior depending on the brain region, underlying circuit, and/or experienced stress conditions. Conclusion: A plethora of available genetic tools, including conventional and conditional mouse mutants targeting CRF system components, has greatly advanced our understanding about the endogenous mecha-nisms underlying HPA system regulation and CRF/UCN-related neuronal circuits involved in stress-related behaviors. Yet, the detailed pathways and molecular mechanisms by which the CRF/UCN-system translates negative or positive stimuli into the final, integrated biological response are not completely un-derstood. The utilization of future complementary methodologies, such as cell-type specific Cre-driver lines, viral and optogenetic tools will help to further dissect the function of genetically defined CRF/UCN neurocircuits in the context of

  15. Japan’s Self Defense Forces After the Great East Japan Earthquake: Toward a New Status Quo

    Science.gov (United States)

    2012-03-01

    Retrenchment, SDF Status Quo, Humanitarian Aid Disaster Relief, U.S.– Japan Security Alliance, Japanese Economy , Japanese Norms, Pacifism, Anti...Chemical, Biological, Radiological, and Nuclear CRF Central Readiness Force DDF Dynamic Defense Force DPJ Democratic Party of Japan EAC East...LNG Liquefied Natural Gas METI Ministry of Economy , Trade, and Industry MINUSTAH United Nations Stabilization Mission in Haiti MOD Ministry

  16. Quantitative proteomics reveals the central changes of wheat in response to powdery mildew.

    Science.gov (United States)

    Fu, Ying; Zhang, Hong; Mandal, Siddikun Nabi; Wang, Changyou; Chen, Chunhuan; Ji, Wanquan

    2016-01-01

    Powdery mildew (Pm), caused by Blumeria graminis f. sp. tritici (Bgt), is one of the most important crop diseases, causing severe economic losses to wheat production worldwide. However, there are few reports about the proteomic response to Bgt infection in resistant wheat. Hence, quantitative proteomic analysis of N9134, a resistant wheat line, was performed to explore the molecular mechanism of wheat in defense against Bgt. Comparing the leaf proteins of Bgt-inoculated N9134 with that of mock-inoculated controls, a total of 2182 protein-species were quantified by iTRAQ at 24, 48 and 72h postinoculation (hpi) with Bgt, of which 394 showed differential accumulation. These differentially accumulated protein-species (DAPs) mainly included pathogenesis-related (PR) polypeptides, oxidative stress responsive proteins and components involved in primary metabolic pathways. KEGG enrichment analysis showed that phenylpropanoid biosynthesis, phenylalanine metabolism and photosynthesis-antenna proteins were the key pathways in response to Bgt infection. InterProScan 5 and the Gibbs Motif Sampler cluster 394 DAPs into eight conserved motifs, which shared leucine repeats and histidine sites in the sequence motifs. Moreover, eight separate protein-protein interaction (PPI) networks were predicted from STRING database. This study provides a powerful platform for further exploration of the molecular mechanism underlying resistant wheat responding to Bgt. Powdery mildew, caused by Blumeria graminis f. sp. tritici (Bgt), is a destructive pathogenic disease in wheat-producing regions worldwide, resulting in severe yield reductions. Although many resistant wheat varieties have been cultivated, there are few reports about the proteomic response to Bgt infection in resistant wheat. Therefore, an iTRAQ-based quantitative proteomic analysis of a resistant wheat line (N9134) in response to Bgt infection has been performed. This paper provides new insights into the underlying molecular

  17. Analysis of energy intensity in Japan

    International Nuclear Information System (INIS)

    Okajima, Shigeharu; Okajima, Hiroko

    2013-01-01

    This study discusses the causes of the increase in Japan's energy intensity, defined as energy consumption divided by GDP, since the early 1990s. The significant reduction in Japan's energy intensity ceased in the early 1980s and has even slightly increased since the early 1990s, indicating that Japan seemingly stopped taking aggressive action to improve energy use. However, further analysis at prefecture level and sector level provides additional insight on energy intensity trends. To analyze the causes of the increase in Japan's energy intensity, energy intensity is decomposed into energy efficiency (improvements in energy efficiency) and energy activity (structural changes from the secondary sector to the tertiary sector of the economy). Our result indicates that the non-uniform energy intensity trends between prefectures are attributed to a high variability in energy efficiency. At sector level, we estimate the income elasticity of energy consumption in each sector and find that a structural change in energy consumption behaviors occurred in all sectors at different time points. The industrial sector and commercial sector became less energy efficient after 1981 and 1988, respectively, which is presumably responsible for the deterioration of Japan's energy intensity since the early 1990s. - Highlights: • We examine why the reduction in Japan's energy intensity increased in the early 1990s. • There is a high variability in energy intensity trends between regions. • The structural changes in energy consumption behaviors occurred in sector level. • These changes may be responsible for the deterioration of Japan's energy intensity

  18. Central leptin action on euglycemia restoration in type 1 diabetes: Restraining responses normally induced by fasting?

    Science.gov (United States)

    Xu, Yuanzhong; Tong, Qingchun

    2017-07-01

    Leptin monotherapy is sufficient to restore euglycemia in insulinopenic type 1 diabetes (T1D), yet the underlying mechanism remains poorly understood. Accumulating evidence demonstrates that the brain mediates the leptin action on euglycemia restoration. Here, we first review evidence supporting that symptoms in T1D resemble an uncontrolled response to fasting. Then, we discuss recent research progress on brain neurons and their neurotransmitters that potentially mediate the leptin action. Finally, peripheral effective pathways, which are normally involved in fasting responses and associated with leptin action on euglycemia restoration in T1D, will also be discussed. This summary complements several previous excellent reviews on this topic (Meek and Morton, 2016; Perry et al., 2016; Fujikawa and Coppari, 2015). A deep understanding of neurocircuitry and the peripheral effective pathways that mediate the leptin action on euglycemia restoration will likely lead to novel targets for an insulin-independent therapeutics against T1D. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Deflecting Hurakan: Enhancing DOD and DOS Interagency Hurricane Response Operations in Central America

    Science.gov (United States)

    2010-04-01

    a large-scale, extended response disaster such as massive floods and landslides produced from hurricanes, it may be necessary for the USAID/OFDA...national power to synergistically leverage their independent capabilities to counter the devastating first, second, and third order effects produced by...humanitarian assistance abroad. The first disaster occurred in March when Costa Rica endured an eruption of the Irazú volcano resulting in

  20. Macrophage biology plays a central role during ionizing radiation-elicited tumor response

    Directory of Open Access Journals (Sweden)

    Qiuji Wu

    2017-08-01

    Full Text Available Radiation therapy is one of the major therapeutic modalities for most solid tumors. The anti-tumor effect of radiation therapy consists of the direct tumor cell killing, as well as the modulation of tumor microenvironment and the activation of immune response against tumors. Radiation therapy has been shown to promote immunogenic cells death, activate dendritic cells and enhance tumor antigen presentation and anti-tumor T cell activation. Radiation therapy also programs innate immune cells such as macrophages that leads to either radiosensitization or radioresistance, according to different tumors and different radiation regimen studied. The mechanisms underlying radiation-induced macrophage activation remain largely elusive. Various molecular players such as NF-κB, MAPKs, p53, reactive oxygen species, inflammasomes have been involved in these processes. The skewing to a pro-inflammatory phenotype thus results in the activation of anti-tumor immune response and enhanced radiotherapy effect. Therefore, a comprehensive understanding of the mechanism of radiation-induced macrophage activation and its role in tumor response to radiation therapy is crucial for the development of new therapeutic strategies to enhance radiation therapy efficacy.

  1. Antiviral type I and type III interferon responses in the central nervous system.

    Science.gov (United States)

    Sorgeloos, Frédéric; Kreit, Marguerite; Hermant, Pascale; Lardinois, Cécile; Michiels, Thomas

    2013-03-15

    The central nervous system (CNS) harbors highly differentiated cells, such as neurons that are essential to coordinate the functions of complex organisms. This organ is partly protected by the blood-brain barrier (BBB) from toxic substances and pathogens carried in the bloodstream. Yet, neurotropic viruses can reach the CNS either by crossing the BBB after viremia, or by exploiting motile infected cells as Trojan horses, or by using axonal transport. Type I and type III interferons (IFNs) are cytokines that are critical to control early steps of viral infections. Deficiencies in the IFN pathway have been associated with fatal viral encephalitis both in humans and mice. Therefore, the IFN system provides an essential protection of the CNS against viral infections. Yet, basal activity of the IFN system appears to be low within the CNS, likely owing to the toxicity of IFN to this organ. Moreover, after viral infection, neurons and oligodendrocytes were reported to be relatively poor IFN producers and appear to keep some susceptibility to neurotropic viruses, even in the presence of IFN. This review addresses some trends and recent developments concerning the role of type I and type III IFNs in: i) preventing neuroinvasion and infection of CNS cells; ii) the identity of IFN-producing cells in the CNS; iii) the antiviral activity of ISGs; and iv) the activity of viral proteins of neurotropic viruses that target the IFN pathway.

  2. Cool-Season Turfgrass Species and Cultivars: Response to Simulated Traffic in Central Italy

    Directory of Open Access Journals (Sweden)

    Carlo F. Cereti

    2010-03-01

    Full Text Available Turfgrass species differ greatly in their ability to withstand the abrasion and compaction of traffic. Wear tolerance of turfgrass species and cultivars has been evaluated abroad by many researchers, while only few and partial studies have been conducted in Italy. Field experiment was carried out in Viterbo in 2001, 2002 and 2003 to evaluate the effect of the simulated traffic on 110 varieties belonging to four turfgrass cool-season species: tall fescue (Festuca arundinacea Schreb., fine fescues (Festuca rubra L. ssp. rubra Gaud., ssp. commutata Gaud., ssp. tricophylla Gaud., perennial ryegrass (Lolium perenne L. and Kentucky bluegrass (Poa pratensis L.. Shoot density, visual turfgrass quality and thatch thickness were the major characters recorded to estimate wear tolerance. Traffic was simulated using a device containing three rollers pulled by a small tractor. The traffic simulator weighed 564 kg and applied a pressure of about 3 MPa. Results indicated that perennial ryegrass and tall fescue had high wear tolerance and low statistical variation among cultivars. Kentucky bluegrass showed an average wear tolerance owing to its shoot density and good recovery potential. In spite of their high shoot density, fine fescues exhibited poor wear tolerance because of their scarce resistance to high temperatures which are typical of the Mediterranean climate in late spring and summer. This study enabled a preliminary selection of the most suitable cool-season grasses and cultivars for trafficked and non-trafficked areas in Central Italy and highlighted that different turfgrass species have different wear tolerance mechanisms.

  3. Antiviral Type I and Type III Interferon Responses in the Central Nervous System

    Directory of Open Access Journals (Sweden)

    Thomas Michiels

    2013-03-01

    Full Text Available The central nervous system (CNS harbors highly differentiated cells, such as neurons that are essential to coordinate the functions of complex organisms. This organ is partly protected by the blood-brain barrier (BBB from toxic substances and pathogens carried in the bloodstream. Yet, neurotropic viruses can reach the CNS either by crossing the BBB after viremia, or by exploiting motile infected cells as Trojan horses, or by using axonal transport. Type I and type III interferons (IFNs are cytokines that are critical to control early steps of viral infections. Deficiencies in the IFN pathway have been associated with fatal viral encephalitis both in humans and mice. Therefore, the IFN system provides an essential protection of the CNS against viral infections. Yet, basal activity of the IFN system appears to be low within the CNS, likely owing to the toxicity of IFN to this organ. Moreover, after viral infection, neurons and oligodendrocytes were reported to be relatively poor IFN producers and appear to keep some susceptibility to neurotropic viruses, even in the presence of IFN. This review addresses some trends and recent developments concerning the role of type I and type III IFNs in: i preventing neuroinvasion and infection of CNS cells; ii the identity of IFN-producing cells in the CNS; iii the antiviral activity of ISGs; and iv the activity of viral proteins of neurotropic viruses that target the IFN pathway.

  4. The central responsiveness of the acute cerveau isolé rat.

    Science.gov (United States)

    User, P; Gottesmann, C

    1982-01-01

    The electrophysiological patterns of the frontal cortex and dorsal hippocampus were studied in the acute cerveau isolé rat. Central and peripheral stimulations were performed in order to modulate these patterns. The results showed that the permanent alternation of high amplitude spindle bursts and low voltage activity in the anterior neocortex of the acute cerveau isolé was influenced neither by olfactory nor by posterior hypothalamic stimulation. In contrast, these two kinds of stimulation easily modulated the continuous low frequency theta rhythm, recorded in the dorsal hippocampus, in terms of amplitude and in overall frequency. This modulation of the theta rhythm in the acute cerveau isolé rat mimics the changes observed when the normal rat comes from the intermediate stage of sleep (as characterized in the the acute intercollicular transected rat by high amplitude spindle bursts at frontal cortex level and low frequency theta activity in the dorsal hippocampus) to rapid sleep. These results further suggest that, during the intermediate stage (as in the cerveau isolé preparation), the hippocampus montonous theta activity appears through a brainstem disinhibitory process releasing the forebrain limbic pacemaker(s). During the following rapid sleep phase, the theta rhythm would be modulated by pontine activity influences acting on the theta generators.

  5. Effects of lidocaine injections into the lateral parabrachial nucleus on dipsogenic and pressor response to central angiotensin 2 in rats

    Science.gov (United States)

    Menani, Jose Vanderlei; Beltz, Terry G.

    1995-01-01

    This study investigated the effects of bilateral injections of the local anesthetic, lidocaine, into the lateral parabrachial nucleus (LPBN) on the dipsogenic and pressor responses induced by intracerebroventricular (i.c.v.) injection of angiotensin 2 (ANG 2). Centrally injected ANG 2 (50 ng/1 microliter) induced water intake ( IO.2 +/- 0.8 ml/h) and pressor responses (22 +/- 1 mmHg). Prior bilateral injection of 10% lidocaine (200 nl) into the LPBN increased the water intake (14.2 +/- 1.4 ml/h), but did not change the pressor response (17 +/- 1 mmHg) to i.c.v. ANG 2. Lidocaine alone injected into the LPBN also induced a pressor response (23 +/- 3 mmHg). These results showing that bilateral LPBN injection of lidocaine increase water intake induced bv i.c.v. ANG 2 are consistent with electrolytic and neurotoxic lesion studies and suggest that the LPBN is associated with inhibitory mechanisms controlling water intake induced by ANG 2. These results also provide evidence that it is feasible to reversibly anesthetize this brain area to facilitate fluid-related ingestive behavior.

  6. Late Pliocene Northern Hemisphere glaciations: The continental and marine responses in the central Mediterranean

    Science.gov (United States)

    Nebout, Nathalie Combourieu; Grazzini, Colette Vergnaud

    Detailed pollen analyses and oxygen isotope records of three foraminiferal species, Globigerina bulloides, Uvigerina peregrina and Cibicides pachyderma, from the Semaforo and Vrica composite sections (Crotone, southern Italy) have been compared to the global climatic changes depicted by late Pliocene-early Pleistocene foraminiferal δ 18O records of Site 607 in the North Atlantic, and Hole 653A in the Tyrrhenian basin, West Mediterranean. Major overturns in the mid-altitude vegetation are shown near isotopic stages 82, 60, 58 and 50, at about 2.03 Ma, 1.6 Ma and 1.37 Ma according to the Raymo et al. (1989) and Ruddiman et al. (1989) timescales. At the same dates, glacial 18O maxima either became higher or display step increases in the western Mediterranean or in the open ocean as well. This suggests that size increases of Northern Hemisphere ice sheets were the driving factor for regional or local marine and continental environmental changes within the Mediterranean basin. Near isotopic stages 62-60, close to the conventional Plio-Pleistocene boundary, the climatic conditions severed enough within the Mediterranean basin to modify the continental environment, as depicted by a sudden increase of Artemisia percentages, while the first significant southward migration of the North Polar Front may have been recorded by an influx of left coiling Neogloboquadrina pachyderma in the central Mediterranean. It also appears that 'Boreal Guests' entered the Mediterranean during phases of 18O enrichment of foraminiferal calcite. There does not seem to be any discrepancy between the climatic concept of the Pliocene-Pleistocene boundary and its chronostratigraphic definition.

  7. Sex-specific association between functional neuropeptide S receptor gene (NPSR1) variants and cortisol and central stress responses.

    Science.gov (United States)

    Streit, Fabian; Akdeniz, Ceren; Haddad, Leila; Kumsta, Robert; Entringer, Sonja; Frank, Josef; Yim, Ilona S; Zänkert, Sandra; Witt, Stephanie H; Kirsch, Peter; Rietschel, Marcella; Wüst, Stefan

    2017-02-01

    The brain neuropeptide S (NPS) system has recently generated substantial interest and may be of major relevance for central stress regulation. The NPS receptor (NPSR1) is highly expressed in the limbic system, exogenous NPS exerts pronounced anxiolytic and fear-attenuating effects in rodents and extensive close crosstalk between the NPS system and the hypothalamic-pituitary-adrenal (HPA) axis has been demonstrated. In humans, associations between NPSR1 variants and anxiety and panic disorder, as well as amygdala responsiveness to fear- relevant faces and prefrontal cortex activity in a fear conditioning paradigm have been reported. Moreover, a NPSR1 sequence variant was found to be associated with cortisol stress responses in males. Here, we performed a haplotype-based analysis covering three functional NPSR1 single nucleotide polymorphisms in the promoter (rs2530547), in exon 3 (rs324981) and exon 6 (rs727162) in 277 healthy subjects who were exposed to the Trier Social Stress Test (TSST). A significant sex-specific association with salivary cortisol responses to acute psychosocial stress was detected for the common TTC haplotype 2 (frequency of about 20%). In an additional study using an imaging genetics approach, 65 healthy subjects were exposed to a stress paradigm for scanner environments (“ScanSTRESS”). We found a significant and, again, sex-specific interaction between rs324981 (whose minor T-allele is harbored by haplotype 2) and the neural stress response in a cluster close to the parahippocampal gyrus (whole brain corrected). Moreover, as in the TSST sample, NPSR1 variation was associated with salivary cortisol responses (on a trend level) in a sex-specific way. In summary, our preliminary findings in two independent cohorts exposed to different stress paradigms suggest that the NPS system significantly influences acute stress responses and that sequence variation in NPSR1 may contribute to sex differences in stress regulation. Copyright © 2016

  8. Anterograde transneuronal viral tract tracing reveals central sensory circuits from brown fat and sensory denervation alters its thermogenic responses.

    Science.gov (United States)

    Vaughan, Cheryl H; Bartness, Timothy J

    2012-05-01

    Brown adipose tissue (BAT) thermogenic activity and growth are controlled by its sympathetic nervous system (SNS) innervation, but nerve fibers containing sensory-associated neuropeptides [substance P, calcitonin gene-related peptide (CGRP)] also suggest sensory innervation. The central nervous system (CNS) projections of BAT afferents are unknown. Therefore, we used the H129 strain of the herpes simplex virus-1 (HSV-1), an anterograde transneuronal viral tract tracer used to delineate sensory nerve circuits, to define these projections. HSV-1 was injected into interscapular BAT (IBAT) of Siberian hamsters and HSV-1 immunoreactivity (ir) was assessed 24, 48, 72, 96, and 114 h postinjection. The 96- and 114-h groups had the most HSV-1-ir neurons with marked infections in the hypothalamic paraventricular nucleus, periaqueductal gray, olivary areas, parabrachial nuclei, raphe nuclei, and reticular areas. These sites also are involved in sympathetic outflow to BAT suggesting possible BAT sensory-SNS thermogenesis feedback circuits. We tested the functional contribution of IBAT sensory innervation on thermogenic responses to an acute (24 h) cold exposure test by injecting the specific sensory nerve toxin capsaicin directly into IBAT pads and then measuring core (T(c)) and IBAT (T(IBAT)) temperature responses. CGRP content was significantly decreased in capsaicin-treated IBAT demonstrating successful sensory nerve destruction. T(IBAT) and T(c) were significantly decreased in capsaicin-treated hamsters compared with the saline controls at 2 h of cold exposure. Thus the central sensory circuits from IBAT have been delineated for the first time, and impairment of sensory feedback from BAT appears necessary for the appropriate, initial thermogenic response to acute cold exposure.

  9. Late winter coccolithophore bloom off central Portugal in response to river discharge and upwelling

    Science.gov (United States)

    Guerreiro, Catarina; Oliveira, Anabela; de Stigter, Henko; Cachão, Mário; Sá, Carolina; Borges, Carlos; Cros, Lluϊsa; Santos, Ana; Fortuño, José-Manuel; Rodrigues, Aurora

    2013-05-01

    Coccolithophore communities collected during late winter (9-19 March of 2010) over the central Portuguese margin showed a major change in species abundance and composition within a few days' time, closely related to the highly transient meteorological and oceanographic conditions. Particularly favourable conditions for coccolithophore growth resulted from late winter continental runoff combined with northerly winds prevailing over the shelf, under clear sky conditions. A nutrient-rich Buoyant Plume (BP) resulting from intense river water runoff prior to and during the start of the cruise, was observed to spread out over the denser winter mixed layer water beneath, and extend equatorwards and offshore under influence of Ekman superficial dynamics. Stabilization of buoyancy, settling of suspended sediment from the BP and the prevailing clear sky conditions in the transition to the 2nd leg of the cruise resulted in optimum conditions for coccolithophores to develop, at the expense of nutrient availability in the superficial sunlit layer. Within a few days, coccolithophore cell densities and associated phytoplankton biomass more than tripled, reaching maximum values of 145,000 cells/l and ~13 µg/l Chl-a, respectively. Often considered as a uniform functional group of calcifying phytoplankton thriving in low-turbulence, low-nutrients and high-light environments, results presented in this study clearly show that coccolithophore life strategies are much more diverse than expected. The increase of cell densities was mainly due to the bloom of Emiliania huxleyi and Gephyrocapsa oceanica in the coastal region west off Cape Carvoeiro, together with other opportunistic phytoplankton genera (Chaetoceros s.l., Thalassiosira s.l and Skeletonema s.l.). This confirms their role as early succession r-selected taxa, capable of rapid growth within nutrient-rich environments. On the contrary, Syracosphaera spp. and Ophiaster spp. displayed the characteristics of K-selected species

  10. Age aspect of adaptive response of the central nervous system in the state of emotional pain

    Directory of Open Access Journals (Sweden)

    Demchenko Ye.M.

    2014-11-01

    Full Text Available The formation of higher adaptive response in the postoperative period was investigated in experiments on rats of two age groups. It was found inhibition of the orientation-motor and emotional activity in young (5-6 months and old rats (20-24 months with the greatear effect in animals of the first age group. In young rats the inhibition of spatial memory was observed – number of food-getting depleted reactions decreased by 28%. Cognitive deficit was accompanied by opposite changes in the content of free unsaturated fatty acids (C18: 2.3, respectively to age features: decreased by 46% in the cortex of young rats and increased by 2.5-fold in the hippocampus of old animals.

  11. Liquid natural gas. Japan

    International Nuclear Information System (INIS)

    Van Kooij, E.

    1998-01-01

    An overview is given of the technical know-how and expertise in Japan with respect to the supply, transport, storage and use of LNG. First the overall energy supply in Japan is outlined. Next, the reasons for the use of LNG as an energy source in Japan are discussed. As an example of a typical LNG-installation in Japan the construction of the Himeji Terminal of Osaka Gas Company is described. Finally, attention is paid to the world's largest and modern below-surface LNG-tanks (capacity of 200,000 m 3 ), installed at the Negishi Terminal of Tokyo Gas Company

  12. Basic concept of the nuclear emergency preparedness and response in Japan after the accident of the Fukushima Dai-ichi Nuclear Power Station. The plain explanation for regional officials and emergency workers

    International Nuclear Information System (INIS)

    Sato, Sohei; Yamamoto, Kazuya

    2013-07-01

    After the accident of TEPCO's Fukushima Dai-ichi Nuclear Power Station occurred on March 11, 2011, actions for controlling the accident and protective actions for the residents like evacuation were taken. In parallel with this, it has been developed to reform the nuclear regulatory systems and the emergency preparedness and response systems in Japan. Especially the Nuclear Regulation Authority's Nuclear Emergency Preparedness and Response Guidelines were adopted with the introducing the basic concepts and the criteria on the basis of the IAEA's safety standards and differed greatly from the prior guidelines. Thus the arrangement of emergency response systems, resources and the operational procedures will be developed complying with according to the guidelines in municipalities around the nuclear power station sites. This work attempts to provide a plain explanation as possible for the regional officials and emergency workers about the basic concepts of the new guidelines. (author)

  13. Behavioral and physiological responses to central administration of corticotropin-releasing factor in the bluebanded goby (Lythrypnus dalli).

    Science.gov (United States)

    Solomon-Lane, Tessa K; Grober, Matthew S

    2012-07-16

    Central manipulation of neuromodulators is critical to establishing causal links between brain function and behavioral output. The absence of a rigorous method of evaluating intracerebroventricular (i.c.v.) injection efficacy in small model organisms is one reason why peripheral administration of neuroactive substances is more common. We use the bluebanded goby (Lythrypnus dalli), a small, highly social fish, to 1) validate our method of i.c.v. injection by testing the hypothesis that corticotropin-releasing factor (CRF) elevates ventilation rate (VR) and 2) propose a novel bioassay using basal physiology and behavior during recovery from anesthesia/i.c.v. administration to assess injection efficacy, neuromodulator activity, and procedural confounds. Central CRF administration significantly increased ventilation rate, demonstrating successful delivery of CRF to the brain. There were no significant differences in cortisol among treatments. The injection procedure did, however, decouple the temporal relationship between the initiation of ventilation and time to regain equilibrium present in control fish. Importantly, neither i.c.v. vehicle nor CRF injection affected the initiation of ventilation, disrupted the stereotyped recovery pattern following anesthesia, or initiated an endocrine stress response. Taken together, we suggest that 1) i.c.v. injection can be effectively used to manipulate central levels of CRF in L. dalli and 2) physiological and behavioral recovery from anesthesia may be used to evaluate injection/technique efficacy. We will use these data in future studies as a measure of effective CRF delivery, to allow for appropriate recovery from i.c.v. injection, and to better evaluate independent effects of CRF on social and/or sexual behavior. Copyright © 2012 Elsevier Inc. All rights reserved.

  14. [Positron emission tomography combined with computed tomography in the initial evaluation and response assessment in primary central nervous system lymphoma].

    Science.gov (United States)

    Mercadal, Santiago; Cortés-Romera, Montserrat; Vélez, Patricia; Climent, Fina; Gámez, Cristina; González-Barca, Eva

    2015-06-08

    To evaluate the role of positron emission tomography combined with computed tomography (PET-CT) in the initial evaluation and response assessment in primary central nervous system lymphoma (PCNSL). Fourteen patients (8 males) with a median age 59.5 years diagnosed of PCNSL. A brain PET-CT and magnetic resonance imaging (MRI) were performed in the initial evaluation. In 7 patients a PET-CT after treatment was performed. PET-CT showed at diagnosis 31 hypermetabolic focuses and MRI showed 47 lesions, with a good grade of concordance between both (k = 0.61; P = .005). In the response assessment, correlation between both techniques was good, and PET-CT was helpful in the appreciation of residual MRI lesions. Overall survival at 2 years of negative vs. positive PET-CT at the end of treatment was 100 vs. 37.5%, respectively (P = .045). PET-CT can be useful in the initial evaluation of PCNSL, and especially in the assessment of response. Despite the fact that PET-CT detects less small lesions than MRI, a good correlation between MRI and PET-CT was observed. It is effective in the evaluation of residual lesions. Prospective studies are needed to confirm their possible prognostic value. Copyright © 2014 Elsevier España, S.L.U. All rights reserved.

  15. Hyperthermic responses to central injections of some peptide and non-peptide opioids in the guinea-pig

    Science.gov (United States)

    Kandasamy, S. B.; Williams, B. A.

    1983-01-01

    The intracerebroventricular administration of prototype nonpeptide opioid receptor (mu, kappa, and sigma) agonists, morphine, ketocyclazocine, and N-allyl normetazocine and an agonist at both kappa and sigma receptors, pentazocine, was found to induce hyperthermia in guinea pigs. The similar administration of peptide opioids like beta endorphin, methionine endkephalin, leucine endkephaline, and several of their synthetic analogues was also found to cause hyperthermia. Only the liver-like transport system of the three anion transport systems (iodide, hippurate, and liver-like) present in the choroid plexus was determined to be important to the central inactivation of beta-endorphin and two synthetic analogues. Prostaglandins and norepinephrine (NE) as well as cAMP were not involved in peptide and nonpeptide opioid-induced hyperthermia. Naloxone-sensitive receptors were found to be involved in the induction of hyperthermia by morphine and beta-endorphin, while hyperthermic responses to ketocyclazocine, N-allyl normetazocine, pentazocine, Met-enkephalin, Leu-enkephalin, and two of the synthetic analogues were not antagonized by nalozone. The lack of antagonism of naloxone on pyrogen, arachidonic acid, PGE2, dibutyryl cAMP, and NE-induced hyperthermia shows that endogenous opioid peptides are not likely to be central mediators of the hyperthermia induced by these agents.

  16. Gastric electrical stimulation decreases gastric distension-induced central nociception response through direct action on primary afferents.

    Directory of Open Access Journals (Sweden)

    Wassila Ouelaa

    Full Text Available BACKGROUND & AIMS: Gastric electrical stimulation (GES is an effective therapy to treat patients with chronic dyspepsia refractory to medical management. However, its mechanisms of action remain poorly understood. METHODS: Gastric pain was induced by performing gastric distension (GD in anesthetized rats. Pain response was monitored by measuring the pseudo-affective reflex (e.g., blood pressure variation, while neuronal activation was determined using c-fos immunochemistry in the central nervous system. Involvement of primary afferents was assessed by measuring phosphorylation of ERK1/2 in dorsal root ganglia. RESULTS: GES decreased blood pressure variation induced by GD, and prevented GD-induced neuronal activation in the dorsal horn of the spinal cord (T9-T10, the nucleus of the solitary tract and in CRF neurons of the hypothalamic paraventricular nucleus. This effect remained unaltered within the spinal cord when sectioning the medulla at the T5 level. Furthermore, GES prevented GD-induced phosphorylation of ERK1/2 in dorsal root ganglia. CONCLUSIONS: GES decreases GD-induced pain and/or discomfort likely through a direct modulation of gastric spinal afferents reducing central processing of visceral nociception.

  17. Hemodynamic and ADH responses to central blood volume shifts in cardiac-denervated humans

    Science.gov (United States)

    Convertino, V. A.; Thompson, C. A.; Benjamin, B. A.; Keil, L. C.; Savin, W. M.; Gordon, E. P.; Haskell, W. L.; Schroeder, J. S.; Sandler, H.

    1990-01-01

    Hemodynamic responses and antidiuretic hormone (ADH) were measured during body position changes designed to induce blood volume shifts in ten cardiac transplant recipients to assess the contribution of cardiac and vascular volume receptors in the control of ADH secretion. Each subject underwent 15 min of a control period in the seated posture, then assumed a lying posture for 30 min at 6 deg head down tilt (HDT) followed by 20 min of seated recovery. Venous blood samples and cardiac dimensions (echocardiography) were taken at 0 and 15 min before HDT, 5, 15, and 30 min of HDT, and 5, 15, and 30 min of seated recovery. Blood samples were analyzed for hematocrit, plasma osmolality, plasma renin activity (PRA), and ADH. Resting plasma volume (PV) was measured by Evans blue dye and percent changes in PV during posture changes were calculated from changes in hematocrit. Heart rate (HR) and blood pressure (BP) were recorded every 2 min. Results indicate that cardiac volume receptors are not the only mechanism for the control of ADH release during acute blood volume shifts in man.

  18. Sensitivity study of rock mass response to glaciation at Finnsjoen, central Sweden

    International Nuclear Information System (INIS)

    Israelsson, J.; Rosengren, L.; Stephansson, O.

    1992-11-01

    The safety analysis SKB-91 of the Swedish Nuclear Fuel and Waste Management Company (SKB) paid specific attention to the glaciation scenario and related phenomena. In the first phase, Rosengren and Stephansson (1990), used the distinct element computer code UDEC to examine the response of the rock mass in the Finnsjoen area to the processes of glaciation and deglaciation. This report describes the second phase, in which the sensitivity of the results to different in situ stresses and fault zone strength properties have been analyzed. A statistical approach was used to extrapolate the range of in-situ stresses at depth from measured in-situ stresses at shallower depths. Three different linear in-situ stress variations with depth were defined using a 99% confidence interval. For each in-situ stress case, three fault zone strength assumptions were analyzed for an ice loading sequence, involving 3 km, 1 km, 0-1 km (ice wedge) and 0 km of ice thickness. Each combination of in-situ stress and fault zone strength was analyzed with and without an ice lake, situated on top of the ice sheet. Consequently, a total of 18 models were studied. The results indicated significant differences in stress distribution, failure (reactivation) of fault zones, and shear displacement on fault zones for some combinations of in-situ stress, fault zone strength, and ice lake pressure. Based on the results, several preliminary recommendations for repository siting are made, as well as recommendations for further study. (authors)

  19. Coral microbial community dynamics in response to anthropogenic impacts near a major city in the central Red Sea

    KAUST Repository

    Ziegler, Maren; Roik, Anna Krystyna; Porter, Adam; Zubier, Khalid; Mudarris, Mohammed S.; Ormond, Rupert; Voolstra, Christian R.

    2016-01-01

    Coral-associated bacteria play an increasingly recognized part in coral health. We investigated the effect of local anthropogenic impacts on coral microbial communities on reefs near Jeddah, the largest city on the Saudi Arabian coast of the central Red Sea. We analyzed the bacterial community structure of water and corals (Pocillopora verrucosa and Acropora hemprichii) at sites that were relatively unimpacted, exposed to sedimentation & local sewage, or in the discharge area of municipal wastewaters. Coral microbial communities were significantly different at impacted sites: in both corals the main symbiotic taxon decreased in abundance. In contrast, opportunistic bacterial families, such as e.g. Vibrionaceae and Rhodobacteraceae, were more abundant in corals at impacted sites. In conclusion, microbial community response revealed a measurable footprint of anthropogenic impacts to coral ecosystems close to Jeddah, even though the corals appeared visually healthy.

  20. Coral microbial community dynamics in response to anthropogenic impacts near a major city in the central Red Sea

    KAUST Repository

    Ziegler, Maren

    2016-01-04

    Coral-associated bacteria play an increasingly recognized part in coral health. We investigated the effect of local anthropogenic impacts on coral microbial communities on reefs near Jeddah, the largest city on the Saudi Arabian coast of the central Red Sea. We analyzed the bacterial community structure of water and corals (Pocillopora verrucosa and Acropora hemprichii) at sites that were relatively unimpacted, exposed to sedimentation & local sewage, or in the discharge area of municipal wastewaters. Coral microbial communities were significantly different at impacted sites: in both corals the main symbiotic taxon decreased in abundance. In contrast, opportunistic bacterial families, such as e.g. Vibrionaceae and Rhodobacteraceae, were more abundant in corals at impacted sites. In conclusion, microbial community response revealed a measurable footprint of anthropogenic impacts to coral ecosystems close to Jeddah, even though the corals appeared visually healthy.

  1. Chronic blood pressure and appetite responses to central leptin infusion in rats fed a high fat diet.

    Science.gov (United States)

    Dubinion, John H; da Silva, Alexandre A; Hall, John E

    2011-04-01

    Obesity has been suggested to induce selective leptin resistance whereby leptin's anorexic effects are attenuated, whereas the effects to increase sympathetic nervous system activity and blood pressure remain intact. Most studies, however, have tested only the acute responses to leptin administration. This study tested whether feeding a high-fat diet causes resistance to the appetite and cardiovascular responses to chronic central leptin infusion. Sprague-Dawley rats were fed high-fat diet (40% kcal from fat, n=5) or normal-fat diet (13% kcal from fat, n=5) for a year. Radiotelemeters were implanted for continuous monitoring of mean arterial pressure (MAP) and heart rate (HR). A 21G steel cannula was implanted in the lateral cerebral ventricle [intracerebroventricular (ICV)]. After recovery, leptin was infused ICV at 0.02 μg/kg per min for 10 days. High-fat rats were heavier than normal-fat rats (582±12 vs. 511±19 g) and exhibited significantly higher MAP (114±3 vs. 96±7 mmHg). Although the acute (24 h) effects of leptin were attenuated in high-fat rats, chronic ICV leptin infusion decreased caloric intake in both groups similarly (50±8 vs. 40±10%) by day 5. Despite decreased food intake and weight loss, leptin infusion significantly increased MAP and HR in both high-fat and normal-fat rats (7±2 and 5±1 mmHg; 18±11 and 21±10 b.p.m., respectively). These results suggest that obesity induced by feeding a high-fat diet blunts the acute anorexic effects of leptin but does not cause significant resistance to the chronic central nervous system effects of leptin on appetite, MAP, or HR.

  2. Streamflow response and sediment yield after farmland abandonment: results from a small experimental catchment in the Central Spanish Pyrenees

    Directory of Open Access Journals (Sweden)

    Serrano-Muela, M. P.

    2010-12-01

    Full Text Available A small catchment affected by agricultural practices in the past, then progressively abandoned and naturally re-vegetated was monitored in the central Spanish Pyrenees. The results obtained over a 9-year period revealed the complexity of its hydrological and geomorphological behaviour. Several runoff generation processes can occur at the same time and in different parts of the catchment, depending on the water reserves conditions and rainfall characteristics. Sediment response is mainly controlled by the spatial and temporal dynamics of water and sediment contributing areas within the catchment. The sediment output illustrates the complexity of the geomorphic response of mountain environments modified by past farmland activities.

    Se presenta una síntesis de la investigación realizada en una pequeña cuenca experimental afectada por una intensa actividad agraria en el pasado y sujeta a un proceso de revegetación natural en la actualidad en el Pirineo Central. Los principales resultados obtenidos demuestran su complejo comportamiento hidrogeomorfológico. El análisis de la información hidrológica sugiere que diferentes procesos dominantes de generación de escorrentía pueden ocurrir de manera simultánea en diferentes áreas de la cuenca, en función del estado de humedad de la misma y de las características de la precipitación. La respuesta sedimentológica está principalmente controlada por la dinámica espacio-temporal de las áreas fuente de escorrentía y de sedimento. La exportación de sedimento ilustra la complejidad de la respuesta geomorfológica en los ambientes de montaña afectados por actividades agrarias en el pasado.

  3. The ANSS response to the Mw 5.8 Central Virginia Seismic Zone earthquake of August 23, 2011

    Science.gov (United States)

    McNamara, D. E.; Horton, S.; Benz, H.; Earle, P. S.; Withers, M. M.; Hayes, G. P.; Kim, W. Y.; Chapman, M. C.; Herrmann, R. B.; Petersen, M. D.; Williams, R. A.

    2011-12-01

    An Mw 5.8 earthquake (depth=6km) occurred on August 23, 2011 (17:51:04 UTC) near Mineral, Virginia, which was widely felt from Maine to Georgia along the eastern seaboard and west to Chicago and western Tennessee. The USGS tallied nearly 142,000 felt reports submitted to the Did You Feel It (DYFI) internet community intensity system, making it the most widely felt earthquake since the web-site began, and demonstrating that more people felt this earthquake than any other in U.S. history. Significant damage was reported in the epicentral area and as far away as Washington D.C. (135 km away); minor damage was reported in Baltimore (200 km). The reverse faulting earthquake occurred on a northeast-striking plane within a region of diffuse seismicity known as the Central Virginia Seismic Zone. Within the first week, the mainshock was followed by 17 aftershocks with magnitude greater than 2, including Mw 4.5, 4.2, and 3.8 events. In the days following the mainshock, 46 portable seismic stations were deployed by several organizations, making this among the best-recorded aftershock sequence in the eastern U.S. Within 24 hours of the mainshock, 8 portable stations were deployed in time to record the largest aftershock to date (M4.5). We will present the results of our post-earthquake response, including attenuation and site amplification observations using portable aftershock station data, details on the initial USGS NEIC post earthquake response products and an assessment of the seismotectonics of the Central Virginia Seismic Zone based on aftershock locations and source parameter modeling of the larger earthquakes.

  4. Epidemiology of diabetes mellitus in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Blackard, W G; Omori, Yoshiaki; Freedman, L R

    1964-03-12

    The clinical and epidemiological features of diabetes mellitus in Japan have been compiled and compared with data from other countries. Diabetes is basically the same in Japan as elsewhere: however, consideration of important differences has led to the following conclusions: The rarity of ketoacidosis in Japan is due to the mild carbohydrate defect present in most diabetics. The mild carbohydrate intolerance in diabetics is probably in part due to a high carbohydrate intake. Diabetic retinopathy is more common in women than in men in Japan; there are limited and conflicting data from the West on this point, but retinopathy, nephropathy and neuropathy occur about as frequently in Japan as in the West. Because of marked dietary differences between Japan and Western countries, these findings suggest that dietary fat has no significance in the pathogenesis of these lesions. Peripheral gangrene is distinctly unusual in Japanese diabetics. This suggests that either: the responsible vascular lesions are different from those responsible for nephropathy and retinopathy; or that small vessel lesions are the same but the lack of large vessel atherosclerosis in the population accounts for the decreased incidence of gangrene. Men have diabetes 2 or 3 times as commonly as women in Japan. If sex-limited inheritance is discarded as a possible reason, it is likely that adult-onset diabetes is more common in men than women except in those countries (the West) where women gain relatively large amounts of weight. The rarity of juvenile diabetes in Japan is best explained by the infrequency of responsible genetic factors. As a consequence, it is likely that juvenile diabetes is caused by different or additional genetic factors which are not significant in adult-onset diabetes. Diabetes prevalance varies sufficiently between different localities in the same country to render the concept of national prevalance of doubtful usefulness. 55 references, 3 figures, 3 tables.

  5. Whistleblowing in Japan.

    Science.gov (United States)

    Davis, Anne J; Konishi, Emiko

    2007-03-01

    This article, written from research data, focuses on the possible meaning of the data rather than on detailed statistical reporting. It defines whistleblowing as an act of the international nursing ethical ideal of advocacy, and places it in the larger context of professional responsibility. The experiences, actions, and ethical positions of 24 Japanese nurses regarding whistleblowing or reporting a colleague for wrongdoing provide the data. Of these respondents, similar in age, educational level and clinical experience, 10 had previously reported another nurse and 12 had reported a physician for a wrongful act. These data raise questions about overt actions to expose a colleague in a culture that values group loyalty and saving face. Additional research is needed for an in-depth understanding of whistleblowing, patient advocacy and professional responsibility across cultures, especially those that value group loyalty, saving face and similar concepts to the Japanese Ishin Denshin, where the value is on implicit understanding requiring indirect communication. Usually, being direct and openly discussing sensitive topics is not valued in Japan because such behavior disrupts the most fundamental value, harmony (wa).

  6. District element modelling of the rock mass response to glaciation at Finnsjoen, central Sweden

    International Nuclear Information System (INIS)

    Rosengren, L.; Stephansson, O.

    1990-12-01

    Six rock mechanics models of a cross section of the Finnsjoen test site have been simulated by means of distinct element analysis and the computer code UDEC. The rock mass response to glaciation, deglaciation, isostatic movements and water pressure from an ice lake have been simulated. Four of the models use a boundary condition with boundary elements at the bottom and sides of the model. This gives a state of stress inside the model which agrees well with the analytical solution where the horizontal and vertical stresses are almost similar. Roller boundaries were applied to two models. This boundary condition cause zero lateral displacement at the model boundaries and the horizontal stress are always less than the vertical stress. Isostatic movements were simulated in one model. Two different geometries of fracture Zone 2 were simulated. Results from modelling the two different geometries show minor changes in stresses, displacements and failure of fracture zones. Under normal pore pressure conditions in the rock mass the weight of the ice load increases the vertical stresses in the models differ depending on the boundary condition. An ice thickness of 3 km and 1 km and an ice wedge of 1 km thickness covering half the top surface of the model have been simulated. For each loading sequence of the six models a complete set of data about normal stress, stress profiles along selected sections, displacements and failure of fracture zones are presented. Based on the results of this study a protection zone of about 100 m width from the outer boundary of stress discontinuity to the repository location is suggested. This value is based on the result that the stress disturbance diminishes at this distance from the outer boundary of the discontinuity. (25 refs.) (authors)

  7. Japan and LPG

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    About 20 million metric tonnes of Liquefied Petroleum Gases (LPG) are consumed each year in Japan, of which 14,5 million metric tonnes are imported from Saudi Arabia and United Arab Emirates. This paper presents LPG industry in Japan and gives informations on the present status: supply and demand, imports, market, distribution

  8. Radial growth of two dominant montane conifer tree species in response to climate change in North-Central China.

    Science.gov (United States)

    Jiang, Yuan; Zhang, Wentao; Wang, Mingchang; Kang, Muyi; Dong, Manyu

    2014-01-01

    North-Central China is a region in which the air temperature has clearly increased for several decades. Picea meyeri and Larix principis-rupprechtii are the most dominant co-occurring tree species within the cold coniferous forest belt ranging vertically from 1800 m to 2800 m a.s.l. in this region. Based on a tree-ring analysis of 292 increment cores sampled from 146 trees at different elevations, this study aimed to examine if the radial growth of the two species in response to climate is similar, whether the responses are consistent along altitudinal gradients and which species might be favored in the future driven by the changing climate. The results indicated the following: (1) The two species grew in different rhythms at low and high elevation respectively; (2) Both species displayed inconsistent relationships between radial growth and climate data along altitudinal gradients. The correlation between radial growth and the monthly mean temperature in the spring or summer changed from negative at low elevation into positive at high elevation, whereas those between the radial growth and the total monthly precipitation displayed a change from positive into negative along the elevation gradient. These indicate the different influences of the horizontal climate and vertical mountainous climate on the radial growth of the two species; (3) The species-dependent different response to climate in radial growth appeared mainly in autumn of the previous year. The radial growth of L. principis-rupprechtii displayed negative responses both to temperature and to precipitation in the previous September, October or November, which was not observed in the radial growth of P. meyeri. (4) The radial growth of both species will tend to be increased at high elevation and limited at low elevation, and L. principis-rupprechtii might be more favored in the future, if the temperature keeps rising.

  9. Radial growth of two dominant montane conifer tree species in response to climate change in North-Central China.

    Directory of Open Access Journals (Sweden)

    Yuan Jiang

    Full Text Available North-Central China is a region in which the air temperature has clearly increased for several decades. Picea meyeri and Larix principis-rupprechtii are the most dominant co-occurring tree species within the cold coniferous forest belt ranging vertically from 1800 m to 2800 m a.s.l. in this region. Based on a tree-ring analysis of 292 increment cores sampled from 146 trees at different elevations, this study aimed to examine if the radial growth of the two species in response to climate is similar, whether the responses are consistent along altitudinal gradients and which species might be favored in the future driven by the changing climate. The results indicated the following: (1 The two species grew in different rhythms at low and high elevation respectively; (2 Both species displayed inconsistent relationships between radial growth and climate data along altitudinal gradients. The correlation between radial growth and the monthly mean temperature in the spring or summer changed from negative at low elevation into positive at high elevation, whereas those between the radial growth and the total monthly precipitation displayed a change from positive into negative along the elevation gradient. These indicate the different influences of the horizontal climate and vertical mountainous climate on the radial growth of the two species; (3 The species-dependent different response to climate in radial growth appeared mainly in autumn of the previous year. The radial growth of L. principis-rupprechtii displayed negative responses both to temperature and to precipitation in the previous September, October or November, which was not observed in the radial growth of P. meyeri. (4 The radial growth of both species will tend to be increased at high elevation and limited at low elevation, and L. principis-rupprechtii might be more favored in the future, if the temperature keeps rising.

  10. Japan reforms its nuclear safety

    International Nuclear Information System (INIS)

    Anon.

    2013-01-01

    The Fukushima Daiichi NPP accident deeply questioned the bases of nuclear safety and nuclear safety regulation in Japan. It also resulted in a considerable loss of public confidence in the safety of nuclear power across the world. Although the accident was caused by natural phenomena, institutional and human factors also largely contributed to its devastating consequences, as shown by the Japanese Diet's and Government's investigation reports. 'Both regulators and licensees were held responsible and decided to fully reconsider the existing approaches to nuclear safety. Consequently, the regulatory system underwent extensive reform based on the lessons learned from the accident,' Yoshihiro Nakagome, the President of Japan Nuclear Energy Safety Organisation, an ETSON member TSO, explains. (orig.)

  11. In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus.

    Science.gov (United States)

    Azevedo, Raimunda S S; de Sousa, Jorge R; Araujo, Marialva T F; Martins Filho, Arnaldo J; de Alcantara, Bianca N; Araujo, Fernanda M C; Queiroz, Maria G L; Cruz, Ana C R; Vasconcelos, Beatriz H Baldez; Chiang, Jannifer O; Martins, Lívia C; Casseb, Livia M N; da Silva, Eliana V; Carvalho, Valéria L; Vasconcelos, Barbara C Baldez; Rodrigues, Sueli G; Oliveira, Consuelo S; Quaresma, Juarez A S; Vasconcelos, Pedro F C

    2018-01-08

    Zika virus (ZIKV) has recently caused a pandemic disease, and many cases of ZIKV infection in pregnant women resulted in abortion, stillbirth, deaths and congenital defects including microcephaly, which now has been proposed as ZIKV congenital syndrome. This study aimed to investigate the in situ immune response profile and mechanisms of neuronal cell damage in fatal Zika microcephaly cases. Brain tissue samples were collected from 15 cases, including 10 microcephalic ZIKV-positive neonates with fatal outcome and five neonatal control flavivirus-negative neonates that died due to other causes, but with preserved central nervous system (CNS) architecture. In microcephaly cases, the histopathological features of the tissue samples were characterized in three CNS areas (meninges, perivascular space, and parenchyma). The changes found were mainly calcification, necrosis, neuronophagy, gliosis, microglial nodules, and inflammatory infiltration of mononuclear cells. The in situ immune response against ZIKV in the CNS of newborns is complex. Despite the predominant expression of Th2 cytokines, other cytokines such as Th1, Th17, Treg, Th9, and Th22 are involved to a lesser extent, but are still likely to participate in the immunopathogenic mechanisms of neural disease in fatal cases of microcephaly caused by ZIKV.

  12. Applying Central Composite Design and Response Surface Methodology to Optimize Growth and Biomass Production of Haemophilus influenzae Type b.

    Science.gov (United States)

    Momen, Seyed Bahman; Siadat, Seyed Davar; Akbari, Neda; Ranjbar, Bijan; Khajeh, Khosro

    2016-06-01

    Haemophilus influenzae type b (Hib) is the leading cause of bacterial meningitis, otitis media, pneumonia, cellulitis, bacteremia, and septic arthritis in infants and young children. The Hib capsule contains the major virulence factor, and is composed of polyribosyl ribitol phosphate (PRP) that can induce immune system response. Vaccines consisting of Hib capsular polysaccharide (PRP) conjugated to a carrier protein are effective in the prevention of the infections. However, due to costly processes in PRP production, these vaccines are too expensive. To enhance biomass, in this research we focused on optimizing Hib growth with respect to physical factors such as pH, temperature, and agitation by using a response surface methodology (RSM). We employed a central composite design (CCD) and a response surface methodology to determine the optimum cultivation conditions for growth and biomass production of H. influenzae type b. The treatment factors investigated were initial pH, agitation, and temperature, using shaking flasks. After Hib cultivation and determination of dry biomass, analysis of experimental data was performed by the RSM-CCD. The model showed that temperature and pH had an interactive effect on Hib biomass production. The dry biomass produced in shaking flasks was about 5470 mg/L, which was under an initial pH of 8.5, at 250 rpm and 35° C. We found CCD and RSM very effective in optimizing Hib culture conditions, and Hib biomass production was greatly influenced by pH and incubation temperature. Therefore, optimization of the growth factors to maximize Hib production can lead to 1) an increase in bacterial biomass and PRP productions, 2) lower vaccine prices, 3) vaccination of more susceptible populations, and 4) lower risk of Hib infections.

  13. Social Mobilization and Community Engagement Central to the Ebola Response in West Africa: Lessons for Future Public Health Emergencies.

    Science.gov (United States)

    Gillespie, Amaya M; Obregon, Rafael; El Asawi, Rania; Richey, Catherine; Manoncourt, Erma; Joshi, Kshiitij; Naqvi, Savita; Pouye, Ade; Safi, Naqibullah; Chitnis, Ketan; Quereshi, Sabeeha

    2016-12-23

    Following the World Health Organization (WHO) declaration of a Public Health Emergency of International Concern regarding the Ebola outbreak in West Africa in July 2014, UNICEF was asked to co-lead, in coordination with WHO and the ministries of health of affected countries, the communication and social mobilization component-which UNICEF refers to as communication for development (C4D)-of the Ebola response. For the first time in an emergency setting, C4D was formally incorporated into each country's national response, alongside more typical components such as supplies and logistics, surveillance, and clinical care. This article describes the lessons learned about social mobilization and community engagement in the emergency response to the Ebola outbreak, with a particular focus on UNICEF's C4D work in Guinea, Liberia, and Sierra Leone. The lessons emerged through an assessment conducted by UNICEF using 4 methods: a literature review of key documents, meeting reports, and other articles; structured discussions conducted in June 2015 and October 2015 with UNICEF and civil society experts; an electronic survey, launched in October and November 2015, with staff from government, the UN, or any partner organization who worked on Ebola (N = 53); and key informant interviews (N = 5). After triangulating the findings from all data sources, we distilled lessons under 7 major domains: (1) strategy and decentralization: develop a comprehensive C4D strategy with communities at the center and decentralized programming to facilitate flexibility and adaptation to the local context; (2) coordination: establish C4D leadership with the necessary authority to coordinate between partners and enforce use of standard operating procedures as a central coordination and quality assurance tool; (3) entering and engaging communities: invest in key communication channels (such as radio) and trusted local community members; (4) messaging: adapt messages and strategies continually as patterns

  14. Hydrogeochemical response of groundwater springs during central Italy earthquakes (24 August 2016 and 26-30 October 2016)

    Science.gov (United States)

    Archer, Claire; Binda, Gilberto; Terrana, Silvia; Gambillara, Roberto; Michetti, Alessandro; Noble, Paula; Petitta, Marco; Rosen, Michael; Pozzi, Andrea; Bellezza, Paolo; Brunamonte, Fabio

    2017-04-01

    Co-seismic hydrological and chemical response at groundwater springs following strong earthquakes is a significant concern in the Apennines, a region in central Italy characterized by regional karstic groundwater systems interacting with active normal faults capable of producing Mw 6.5 to 7.0 seismic events. These aquifers also provide water supply to major metropolitan areas in the region. On August 24, 2016, a Mw 6.0 earthquake hit Central Italy in the area where Latium joins Umbria, Marche and Abruzzi; this was immediately followed one hour later by a Mw 5.4 shock. The epicenter of the event was located at the segment boundary between the Mt. Vettore and Mt. Laga faults. On October 26, 2016 and on October 30, 2016, three other big shocks (Mw 5.5, Mw 6.0 and Mw 6.5) ruptured again the Vettore Fault and its NW extension. Immediately after Aug. 24, we sampled springs discharging different aquifers in the Rieti area, including the Peschiera spring, which feeds the aqueduct of Rome. Thermal springs connected with deep groundwater flowpaths were also sampled. These springs, sampled previously in 2014 and 2015, provide some pre-earthquake data. Moreover, we sampled 4 springs along the Mt. Vettore fault system: 3 small springs at Forca di Presta, close to the trace of the earthquake surface ruptures, and two in Castel Sant'Angelo sul Nera. The latter are feeding the Nera aqueduct and the Nerea S.p.A. mineral water plant, which also kindly allowed us to collect bottled water samples from the pre-seismic period. The aim of this study is to evaluate the strong earthquake sequence effects on the hydrochemistry and flow paths of groundwater from different aquifer settings based on analysis before and after seismic events. The comparison between the responses of springs ca. 40 km from the epicenter (Rieti basin) and the springs located near the epicenter (Castelsantangelo sul Nera and Forca di Presta) is especially significant for understanding the resilience of groundwater

  15. Role of Serum Brain Derived Neurotrophic Factor and Central N-Acetylaspartate for Clinical Response under Antidepressive Pharmacotherapy

    Directory of Open Access Journals (Sweden)

    Sarah Nase

    2016-02-01

    Full Text Available Background: The predictive therapeutic value of brain derived neurotrophic factor (BDNF and its changes associated with the use of specific antidepressants are still unclear. In this study, we examined BDNF as a peripheral and NAA as a central biomarker over the time course of antidepressant treatment to specify both of their roles in the response to the medication and clinical outcome. Methods: We examined serum BDNF (ELISA kit in a sample of 76 (47 female and 29 male depressed patients in a naturalistic setting. BDNF was assessed before medication and subsequently after two, four and six weeks of antidepressant treatment. Additionally, in fifteen patients, N-acetylaspartate (NAA was measured in the anterior cingulate cortex (ACC with magnetic resonance spectroscopy (MRS. Over a time course of six weeks BDNF and NAA were also examined in a group of 41 healthy controls. Results: We found significant lower serum BDNF concentrations in depressed patients compared to the sample of healthy volunteers before and after medication. BDNF and clinical symptoms decreased significantly in the patients over the time course of antidepressant treatment. Serum BDNF levels at baseline predicted the symptom outcome after eight weeks. Specifically, responders and remitters had lower serum BDNF at baseline than the nonresponders and nonremitters. NAA was slightly decreased but not significantly lower in depressed patients when compared with healthy controls. During treatment period, NAA showed a tendency to increase. Limitations: A relative high drop-out rate and possibly, a suboptimal observation period for BDNF. Conclusion: Our data confirm serum BDNF as a biomarker of depression with a possible role in response prediction. However, our findings argue against serum BDNF increase being a prerequisite to depressive symptom reduction.

  16. Factors that predict a positive response on gonadotropin-releasing hormone stimulation test for diagnosing central precocious puberty in girls

    Directory of Open Access Journals (Sweden)

    Junghwan Suh

    2013-12-01

    Full Text Available PurposeThe rapid increase in the incidence of precocious puberty in Korea has clinical and social significance. Gonadotropin-releasing hormone (GnRH stimulation test is required to diagnose central precocious puberty (CPP, however this test is expensive and time-consuming. This study aimed to identify factors that can predict a positive response to the GnRH stimulation test.MethodsClinical and laboratory parameters, including basal serum luteinizing hormone (LH, follicle-stimulating hormone (FSH, and estradiol (E2, were measured in 540 girls with clinical signs of CPP.ResultsTwo hundred twenty-nine of 540 girls with suspected CPP had a peak serum LH level higher than 5 IU/L (the CPP group. The CPP group had advanced bone age (P<0.001, accelerated yearly growth rate (P<0.001, increased basal levels of LH (P=0.02, FSH (P<0.001, E2 (P=0.001, and insulin-like growth factor-I levels (P<0.001 compared to the non-CPP group. In contrast, body weight (P<0.001 and body mass index (P<0.001 were lower in the CPP group. Although basal LH was significantly elevated in the CPP group compared to the non-CPP group, there was considerable overlap between the 2 groups. Cutoff values of basal LH (0.22 IU/L detected CPP with 87.8% sensitivity and 20.9% specificity.ConclusionNo single parameter can predict a positive response on the GnRH stimulation test with both high sensitivity and specificity. Therefore, multiple factors should be considered in evaluation of sexual precocity when deciding the timing of the GnRH stimulation test.

  17. Kirishima, Japan Images

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The shield volcano consists of more than 20 eruptive centers over a 20 x 30 km area that also includes Japan's first national park. Sixty-nine eruptions have been...

  18. The great East Japan earthquake of March 11, 2011, from the vantage point of blood banking and transfusion medicine.

    Science.gov (United States)

    Nollet, Kenneth E; Ohto, Hitoshi; Yasuda, Hiroyasu; Hasegawa, Arifumi

    2013-01-01

    The Great East Japan Earthquake of March 11, 2011, and subsequent tsunami took nearly 20 000 lives in Tohoku, the northeastern part of Japan's main island. Most victims were either carried away by the tsunami or drowned. The ability to collect blood was disrupted on the Pacific coast of Tohoku. Inland areas were less affected, but allogeneic blood collected in Tohoku is tested at the Miyagi Red Cross Blood Center (Miyagi Center) in the coastal city of Sendai. Miyagi Center was damaged and could not test for 2 months. The aims of this study are as follows: (1) to assess transfusion practice at 8 disaster response hospitals in Tohoku's Fukushima Prefecture, for equal intervals before and after March 11, 2011; (2) to report activities related to blood collection and distribution in response to the disaster; and (3) to describe the Great East Japan Earthquake in the context of other disasters. Data were collected through a survey of transfusion services at 8 major disaster response hospitals, communication at transfusion conferences, and literature review. Transfused patients and units transfused were about 70% and 60% of normal in the surveyed hospitals because this was a disaster of mass casualty rather than mass injury, and patients requiring chronic care were evacuated out. A nationally coordinated effort allowed excess blood collected outside Tohoku to be transported in, despite infrastructure damage. Japan's national system of blood collection and distribution responded effectively to local needs after the Great East Japan Earthquake. Disasters such as Japan's 3.11 should guide discourse about emergency preparedness and centralization of services. Copyright © 2013. Published by Elsevier Inc.

  19. Putting Corporate Social Responsibility to Work in Mining Communities: Exploring Community Needs for Central Appalachian Wastewater Treatment

    Directory of Open Access Journals (Sweden)

    Nicholas Cook

    2015-04-01

    Full Text Available Due to the finite nature of non-renewable mineral and energy resources such as coal, resource extraction is inherently unsustainable; however, mining and related activities can contribute to sustainable development. Indeed, the principles of corporate social responsibility (CSR require that mine operators design and conduct their activities in ways that provide for net positive impacts on surrounding communities and environments. In Central Appalachia, there appears to be a particularly ripe opportunity for the coal industry to put CSR to work: participation in sustainable solutions to the long-standing problem of inadequately treated wastewater discharges—which not only represent a potential human health hazard, but also contribute to the relatively high incidence of bacterial impairments in surface waters in the region. In this paper, we outline the underlying factors of this problem and the advantages of industry-aided solutions in a region where limited economic and technical resources are not always aligned with social and environmental needs. We also suggest a framework for problem-solving, which necessarily involves all interested stakeholders, and identify the primary challenges that must be overcome in pursuit of sustainable solutions.

  20. Mobile Marketing in Japan

    OpenAIRE

    Noah H. N. Lynn; Paul D. Berger

    2014-01-01

    In this paper we describe the state of mobile marketing in Japan. We consider the various aspects of mobile marketing in Japan and what has led to the overwhelming adoption by Japanese youth, and to a degree Japanese society as a whole, of social media and associated activities. This growth of mobile marketing has dramatic, positive implications for marketing, in general, as well as for the sale of selected product classes. We also consider markers for suggesting what the future of mobile mar...

  1. In Defense of Japan

    Science.gov (United States)

    2018-01-03

    potential addition of F-35B STOVL aircraft to their Izumo class helicopter destroyers is a good example. Japan’s conduct during World War II remain locked ...antiwar and antinuclear identity . But after sixty years, Japan’s neighbors still see bayoneted babies. Relations between Japan and its former victims...and the world order Robert Cooper defines Japan as the lone post-modern country surrounded by states firmly locked into an earlier age and that if

  2. Industrial lasers in Japan

    Science.gov (United States)

    Karube, Norio

    1991-03-01

    I am to report on some aspects of industrial lasers in Japan. Mostly centering on the market. In Japan, the history of laser developnent is rather profound. And long. Ever since the first invention of the laser in this country in 1960. This is partly because of the fact that in Japan the spectroscopic studies of the ruby was very popular in the late 1950's. Ever since niost of the work has been done in the research laboratories of the industry, not in the universities or not in the governmental laboratories. And since that time our first activity was mainly centering on the basic research, but after that time we have the evolution of the technology. One of the features in Japan is that the activity of developement and research of laser technology from the very basic phase up to the present commercialization has been done by the same group of people, including ine. We had a national project which ended about six years ago which was sponsored by MITI. MITI is Ministry of International Trade and Industry in Japan. And because of this national project, the effect of this project had a very enlightening effect in Japan. And after that our Japanese laser market became very flourishing.

  3. Responses of a tall building with U.S. code-type instrumentation in Tokyo, Japan, to events before, during and after the Tohoku earthquake of 11 March 2011

    Science.gov (United States)

    Çelebi, Mehmet; Kashima, Toshihide; Ghahari, S. Farid; Abazarsa, Fariba; Taciroglu, Ertugrul

    2016-01-01

    The 11 March 2011 M 9.0 Tohoku earthquake generated long-duration shaking that propagated hundreds of kilometers from the epicenter and affected tall buildings in urban areas several hundred kilometers from the epicenter of the main shock. Recorded responses show that tall buildings were affected by long-period motions. This study presents the behavior and performance of a 37-story building in the Tsukuda area of Tokyo, Japan, as inferred from modal analyses of records retrieved for a time interval covering a few days before, during, and for several months after the main shock. The U.S. “code-type” array comprises three triaxial accelerometers deployed at three levels in the superstructure. Such a sparse array in a tall structure limits a reliable assessment, because its performance must be based on only the average drift ratios. Based on the inferred values of this parameter, the subject building was not structurally damaged.

  4. 300 years of hydrological records and societal responses to droughts and floods on the Pacific coast of Central America

    Science.gov (United States)

    Guevara-Murua, Alvaro; Williams, Caroline A.; Hendy, Erica J.; Imbach, Pablo

    2018-02-01

    The management of hydrological extremes and impacts on society is inadequately understood because of the combination of short-term hydrological records, an equally short-term assessment of societal responses and the complex multi-directional relationships between the two over longer timescales. Rainfall seasonality and inter-annual variability on the Pacific coast of Central America is high due to the passage of the Inter Tropical Convergence Zone (ITCZ) and the El Niño-Southern Oscillation (ENSO). Here we reconstruct hydrological variability and demonstrate the potential for assessing societal impacts by drawing on documentary sources from the cities of Santiago de Guatemala (now Antigua Guatemala) and Guatemala de la Asunción (now Guatemala City) over the period from 1640 to 1945. City and municipal council meetings provide a rich source of information dating back to the beginning of Spanish colonisation in the 16th century. We use almost continuous sources from 1640 AD onwards, including > 190 volumes of Actas de Cabildo and Actas Municipales (minutes of meetings of the city and municipal councils) held by the Archivo Histórico de la Municipalidad de Antigua Guatemala (AHMAG) and the Archivo General de Centro América (AGCA) in Guatemala City. For this 305-year period (with the exception of a total of 11 years during which the books were either missing or damaged), information relating to Catholic rogation ceremonies and reports of flooding events and crop shortages were used to classify the annual rainy season (May to October) on a five-point scale from very wet to very dry. In total, 12 years of very wet conditions, 25 years of wetter than usual conditions, 34 years of drier conditions and 21 years of very dry conditions were recorded. An extended drier period from the 1640s to the 1740s was identified and two shorter periods (the 1820s and the 1840s) were dominated by dry conditions. Wetter conditions dominated the 1760s-1810s and possibly record more

  5. Core Indicators of Japan's Consumer Price Index

    OpenAIRE

    Shigenori Shiratsuka

    2006-01-01

    The primary objective of the Bank of Japan (BOJ) in conducting monetary policy is to promote sustainable growth by achieving price stability. The price stability that needs to be achieved is regarded as not just short-term and temporary, but sustainable in the medium to long term, which is the common understanding among major central banks. To fulfill this mandate, the BOJ is required to identify the underlying trend of inflation by excluding various idiosyncratic disturbances from measured p...

  6. Introductory Overview of Stone Heritages in Japan

    Science.gov (United States)

    Kato, Hirokazu; Oikawa, Teruki; Fujita, Masayo; Yokoyama, Shunji

    2013-04-01

    As one contribution to 'Global Heritage Stone Resources' (GHSR), some stone heritages in Japan, which are nominated in the interim list, are briefly introduced. The geology of Japanese Islands where are the one of the most active areas in the history of the Earth, is very complicated. Therefore Japanese Islands consist of various kinds of minerals and rocks. Some of them were used to make stone implements and accessories. Japanese people also used to the best possible advantage to built tombstone, gate, pavement ,and the basement and wall of the large building such as temples, shrines, castles and modern buildings. 1. Stone Heritages of Pre-historical age: In the late Pleistocene and the early Holocene, ancient Japanese used obsidian cooled rapidly from rhyolitic magma.to make small implements and accessories. For example, Shirataki, Hokkaido (north island) is the largest place producing obsidian in Japan where Paleolithic people made arrowhead, knives and so on. Another example, Jade yielded in Itoigawa City, Japan Sea coast of central Japan, was made in the metamorphic rock about five hundred million years ago. Itoigawa area is only one place where jade is abundantly produced in Japan. Ancient people had been already collected and processed to ornaments although it is very hard and traded in wide area more than several thousand years ago. 2. Stone Heritages of Historical age: 2.1 Archaeological remains: In the Kofun (old mound) period (250 to 538 AD), stone burial chambers were used for old mounds to preserve against the putrefaction and to protect from the theft. For example, Ishibutai Kofun ("ishi" means "stone" and "butai" means "stage") in Nara old capital city, southwest Japan, is the largest known megalithic structure made of granite in Japan. 2.2 Stone walls of some typical castles Stones used is because of not only the rich reserves of rocks but also restriction of transportation. Osaka (second biggest city) castle, are composed of Cretaceous granite

  7. Systematic review including re-analyses of 1148 individual data sets of central venous pressure as a predictor of fluid responsiveness

    DEFF Research Database (Denmark)

    Eskesen, T G; Wetterslev, M; Perner, A

    2016-01-01

    PURPOSE: Central venous pressure (CVP) has been shown to have poor predictive value for fluid responsiveness in critically ill patients. We aimed to re-evaluate this in a larger sample subgrouped by baseline CVP values. METHODS: In April 2015, we systematically searched and included all clinical...

  8. Institutional perceptions, adaptive capacity and climate change response in a post-conflict country: a case study from Central African Republic

    NARCIS (Netherlands)

    Brown, H.C.P.; Smit, B.; Somorin, O.A.; Sonwa, D.J.; Ngana, F.

    2013-01-01

    The Central African Republic (CAR) faces increased vulnerability to climate change because it is a low-income country with low adaptive capacity; a situation that is exacerbated by recent civil conflict. This research analysed the perceptions of decision-makers within, and the response of diverse

  9. Proceedings of preparing for a significant Central United States earthquake-Science needs of the response and recovery community

    Science.gov (United States)

    Witt, Emitt C.

    2010-01-01

    Preface Imagine waking up at 2 o'clock in the morning by a violent rumbling that causes ceilings to fall, furniture to topple over, and windows to break. Your home is crumbling, it is dark, and by the time you realize what is going on the shaking stops. You quickly determine that your family members are okay, but you also realize your power is out, all the windows are broken, and there is substantial damage to your home possibly making it unsafe to remain inside. The temperature outside is in the 20s, there is a heavy snow on the ground, and the flu season is at its peak with two of your family members affected. Unfortunately your family is one of thousands in a similar circumstance and the response to your needs may not be immediate, if at all. Could an earthquake like this happen unannounced? It did in the Central United States during the great New Madrid earthquake of 1811-12. A resident of New Madrid, Missouri writes (Martin, 1848 ): 'On the 16th of December 1811, about 2 o'clock, AM, we were visited by a violent shock of an earthquake accompanied by a very awful noise resembling loud but distant thunder, but more hoarse and vibrating, which was followed in a few minutes by the complete saturation of the atmosphere with sulphurious vapor, causing total darkness. The screams of the affrighted inhabitants running to and fro, not knowing where to go, or what to do-the cries of the fowls and beasts of every species-the crackling of trees falling, and the roar of the Mississippi-the current of which was retrograde for a few minutes, owing as is supposed to an irruption in its bed-formed a scene truly horrible.' Eliza Bryan, March 22, 1816 The residents of the Central United States during the great New Madrid earthquake were accustomed to living rugged life styles. Electrical power was not a reality, water was drawn from shallow hand-dug wells or retrieved from streams, food was hunted or grown, and the homes typically were log structures with dirt floors. Though

  10. Together with the farmers: social and rural medicine in Japan.

    Science.gov (United States)

    Abrams, H K

    1978-01-01

    Japan emerged from feudalism a century ago. Farmers comprise 20 percent of the population of 110 million. The agricultural cooperative movement sponsors 118 hospitals in rural areas. Of these, the Saku Central Hospital is the largest, and provides leadership to a vigorous rural health movement. Its unique outreach program and its contributions to rural health are described, together with remarks about Japan's health situation generally. There may be lessons here for America.

  11. Nuclear power in Japan

    International Nuclear Information System (INIS)

    Kishida, J.

    1990-01-01

    The Japanese movement against nuclear energy reached a climax in its upsurge in 1988 two years after the Chernobyl accident. At the outset of that year, this trend was triggered by the government acknowledgement that the Tokyo market was open to foods contaminated by the fallout from Chernobyl. Anti-nuclear activists played an agitating role and many housewives were persuaded to join them. Among many public opinion surveys conducted at that time by newspapers and broadcasting networks, I would like to give you some figures of results from the poll carried out by NHK: Sixty percent of respondents said that nuclear power 'should be promoted', either 'vigorously' 7 or 'carefully' 53%). Sixty-six percent doubted the 'safety of nuclear power', describing it as either 'very dangerous' 20%) or 'rather dangerous' (46%). Only 27% said it was 'safe'. In other words, those who acknowledged the need for nuclear power were almost equal in number with those who found it dangerous. What should these figures be taken to mean? I would take note of the fact that nearly two-thirds of valid responses were in favor of nuclear power even at the time when public opinion reacted most strongly to the impact of the Chernobyl accident. This apparently indicates that the majority of the Japanese people are of the opinion that they would 'promote nuclear power though it is dangerous' or that they would 'promote it, but with the understanding that it is dangerous'. But the anti-nuclear movement is continuing. It remains a headache for both the government and the electric utilities. But we can regard the anti-nuclear movement in Japan as not so serious as that faced by other industrial nations

  12. Nuclear power in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Kishida, J [Japan Research Institute, Ltd., Tokyo (Japan)

    1990-07-01

    The Japanese movement against nuclear energy reached a climax in its upsurge in 1988 two years after the Chernobyl accident. At the outset of that year, this trend was triggered by the government acknowledgement that the Tokyo market was open to foods contaminated by the fallout from Chernobyl. Anti-nuclear activists played an agitating role and many housewives were persuaded to join them. Among many public opinion surveys conducted at that time by newspapers and broadcasting networks, I would like to give you some figures of results from the poll carried out by NHK: Sixty percent of respondents said that nuclear power 'should be promoted', either 'vigorously' 7 or 'carefully' 53%). Sixty-six percent doubted the 'safety of nuclear power', describing it as either 'very dangerous' 20%) or 'rather dangerous' (46%). Only 27% said it was 'safe'. In other words, those who acknowledged the need for nuclear power were almost equal in number with those who found it dangerous. What should these figures be taken to mean? I would take note of the fact that nearly two-thirds of valid responses were in favor of nuclear power even at the time when public opinion reacted most strongly to the impact of the Chernobyl accident. This apparently indicates that the majority of the Japanese people are of the opinion that they would 'promote nuclear power though it is dangerous' or that they would 'promote it, but with the understanding that it is dangerous'. But the anti-nuclear movement is continuing. It remains a headache for both the government and the electric utilities. But we can regard the anti-nuclear movement in Japan as not so serious as that faced by other industrial nations.

  13. Assessment of soil erosion sensitivity and post-timber-harvesting erosion response in a mountain environment of Central Italy

    Science.gov (United States)

    Borrelli, Pasquale; Schütt, Brigitta

    2014-01-01

    This study aimed to assess the effects of forest management on the occurrence of accelerated soil erosion by water. The study site is located in a mountainous area of the Italian Central Apennines. Here, forest harvesting is a widespread forestry activity and is mainly performed on the moderate to steep slopes of the highlands. Through modeling operations based on data on soil properties and direct monitoring of changes in the post-forest-harvesting soil surface level at the hillslope scale, we show that the observed site became prone to soil erosion after human intervention. Indeed, the measured mean soil erosion rate of 49 t ha- 1 yr- 1 for the harvested watershed is about 21 times higher than the rate measured in its neighboring undisturbed forested watershed (2.3 t ha- 1 yr- 1). The erosive response is greatly aggravated by exposing the just-harvested forest, with very limited herbaceous plant cover, to the aggressive attack of the heaviest annual rainfall without adopting any conservation practices. The erosivity of the storms during the first four months of field measurements was 1571 MJ mm h- 1 ha- 1 in total (i.e., from September to December 2008). At the end of the experiment (16 months), 18.8%, 26.1% and 55.1% of the erosion monitoring sites in the harvested watershed recorded variations equal or greater than 0-5, 5-10 and > 10 mm, respectively. This study also provides a quantification of Italian forestland surfaces with the same pedo-lithological characteristics exploited for wood supply. Within a period of ten years (2002-2011), about 9891 ha of coppice forest changes were identified and their potential soil erosion rates modeled.

  14. Phosphodiesterase 9A regulates central cGMP and modulates responses to cholinergic and monoaminergic perturbation in vivo.

    Science.gov (United States)

    Kleiman, Robin J; Chapin, Douglas S; Christoffersen, Curt; Freeman, Jody; Fonseca, Kari R; Geoghegan, Kieran F; Grimwood, Sarah; Guanowsky, Victor; Hajós, Mihály; Harms, John F; Helal, Christopher J; Hoffmann, William E; Kocan, Geralyn P; Majchrzak, Mark J; McGinnis, Dina; McLean, Stafford; Menniti, Frank S; Nelson, Fredrick; Roof, Robin; Schmidt, Anne W; Seymour, Patricia A; Stephenson, Diane T; Tingley, Francis David; Vanase-Frawley, Michelle; Verhoest, Patrick R; Schmidt, Christopher J

    2012-05-01

    Cyclic nucleotides are critical regulators of synaptic plasticity and participate in requisite signaling cascades implicated across multiple neurotransmitter systems. Phosphodiesterase 9A (PDE9A) is a high-affinity, cGMP-specific enzyme widely expressed in the rodent central nervous system. In the current study, we observed neuronal staining with antibodies raised against PDE9A protein in human cortex, cerebellum, and subiculum. We have also developed several potent, selective, and brain-penetrant PDE9A inhibitors and used them to probe the function of PDE9A in vivo. Administration of these compounds to animals led to dose-dependent accumulation of cGMP in brain tissue and cerebrospinal fluid, producing a range of biological effects that implied functional significance for PDE9A-regulated cGMP in dopaminergic, cholinergic, and serotonergic neurotransmission and were consistent with the widespread distribution of PDE9A. In vivo effects of PDE9A inhibition included reversal of the respective disruptions of working memory by ketamine, episodic and spatial memory by scopolamine, and auditory gating by amphetamine, as well as potentiation of risperidone-induced improvements in sensorimotor gating and reversal of the stereotypic scratching response to the hallucinogenic 5-hydroxytryptamine 2A agonist mescaline. The results suggested a role for PDE9A in the regulation of monoaminergic circuitry associated with sensory processing and memory. Thus, PDE9A activity regulates neuronal cGMP signaling downstream of multiple neurotransmitter systems, and inhibition of PDE9A may provide therapeutic benefits in psychiatric and neurodegenerative diseases promoted by the dysfunction of these diverse neurotransmitter systems.

  15. Tropical Pacific Climate, Carbon, and Ocean Biogeochemical Response to the Central American Seaway in a GFDL Earth System Model

    Science.gov (United States)

    Sentman, L. T.; Dunne, J. P.; Stouffer, R. J.; Krasting, J. P.; Wittenberg, A. T.; Toggweiler, J. R.; Broccoli, A. J.

    2017-12-01

    To explore the tropical Pacific climate, carbon, and ocean biogeochemical response to the shoaling and closure of the Central American Seaway during the Pliocene (5.3-2.6 Ma), we performed a suite of sensitivity experiments using the Geophysical Fluid Dynamics Laboratory Earth System Model, GFDL-ESM2G, varying only the seaway widths and sill depths. These novel ESM simulations include near-final closure of the seaway with a very narrow, 1º grid cell wide opening. Net mass transport through the seaway into the Caribbean is 20.5-23.1 Sv with a deep seaway, but only 14.1 Sv for the wide/shallow seaway because of the inter-basin bi-directional horizontal mass transport. Seaway transport originates from the Antarctic Circumpolar Current in the Pacific and rejoins it in the South Atlantic, reducing the Indonesian Throughflow and transporting heat and salt southward into the South Atlantic, in contrast to present-day and previous seaway simulations. Tropical Pacific mean climate and interannual variability is sensitive to the seaway shoaling, with the largest response to the wider/deeper seaway. In the tropical Pacific, the top 300-m warms 0.4-0.8°C, the equatorial east-west sea surface temperature gradient increases, the north-south sea surface temperature asymmetry at 110°W decreases, thermocline deepens 5-11 m, and the east-west thermocline gradient increases. In the Niño-3 region, ENSO amplitude increases, skewed toward more cold (La Niña) events, El Niño and La Niña develops earlier ( 3 months), the annual cycle weakens and the semi-annual and interannual cycles strengthen from increased symmetry of the north-south sea surface temperature gradient, and atmospheric global teleconnections strengthen with the seaway. The increase in global ocean overturning with the seaway results in a younger average ocean ideal age, reduced dissolved inorganic carbon inventory and marine net primary productivity, and altered inter-basin patterns of surface sediment carbonate

  16. Improvement for enhanced xylanase production by Cellulosimicrobium cellulans CKMX1 using central composite design of response surface methodology.

    Science.gov (United States)

    Walia, Abhishek; Mehta, Preeti; Guleria, Shiwani; Shirkot, Chand Karan

    2015-12-01

    The effects of yeast extract (X 1 ), NH 4 NO 3 (X 2 ), peptone (X 3 ), urea (X 4 ), CMC (X 5 ), Tween 20 (X 6 ), MgSO 4 (X 7 ), and CaCO 3 (X 8 ) on production of xylanase from Cellulosimicrobium cellulans CKMX1 were optimized by statistical analysis using response surface methodology (RSM). The RSM was used to optimize xylanase production by implementing the Central composite design. Statistical analysis of the results showed that the linear, interaction and quadric terms of these variables had significant effects. However, only the linear effect of X 4 , X 5 , interaction effect of X 1 X 7 , X 1 X 8 , X 2 X 3 , X 2 X 8 , X 3 X 6 , X 3 X 8 , X 4 X 6 , X 4 X 7 , X 5 X 7 , X 5 X 8 and quadratic effect of X 3 2 , X 5 2 and X 7 2 found to be insignificant terms in the quadratic model and had no response at significant level. The minimum and maximum xylanase production obtained was 331.50 U/g DBP and 1027.65 U/g DBP, respectively. The highest xylanase activity was obtained from Run No. 30, which consisted of yeast extract (X 1 ), 1.00 g (%); NH 4 NO 3 (X 2 ), 0.20 g (%); peptone (X 3 ), 1.00 g (%); urea (X 4 ), 10 mg (%); CMC (X 5 ), 1.00 g (%); Tween 20 (X 6 ), 0.02 mL (%); CaCO 3 (X 7 ), 0.50 g (%) and MgSO 4 (X 8 ), 9.0 g (%). The optimization resulted in 3.1-fold increase of xylanase production, compared with the lowest xylanase production of 331.50 U/g DBP after 72 h of incubation in stationary flask experiment. Application of cellulase-free xylanase in pulp biobleaching from C. cellulans CKMX1 under C-E P -D sequence has been shown to bring about a 12.5 % reduction of chlorine, decrease of 0.8 kappa points (40 %), and gain in brightness was 1.42 % ISO points in 0.5 % enzyme treated pulp as compared to control.

  17. Japan steel mill perspective

    Energy Technology Data Exchange (ETDEWEB)

    Murase, K. [Kobe Steel Ltd., Tokyo (Japan)

    2004-07-01

    The international and Japan's steel industry, the coking coal market, and Japan's expectations from Canada's coal industry are discussed. Japan's steel mills are operating at full capacity. Crude steel production for the first half of 2004 was 55.8 million tons. The steel mills are profitable, but costs are high, and there are difficulties with procuring raw materials. Japan is trying to enhance the quality of coke, in order to achieve higher productivity in the production of pig iron. Economic growth is rising disproportionately in the BRICs (Brazil, Russia, India, and China), with a large increase in coking coal demand from China. On the supply side, there are several projects underway in Australia and Canada to increase production. These include new developments by Elk Valley Coal Corporation, Grande Cache Coal, Western Canadian Coal, and Northern Energy and Mining in Canada. The Elga Mine in the far eastern part of Russia is under development. But the market is expected to remain tight for some time. Japan envisions Canadian coal producers will provide a stable coal supply, expansion of production and infrastructure capabilities, and stabilization of price. 16 slides/overheads are included.

  18. Exposure-response relationship of wind turbine noise with self-reported symptoms of sleep and health problems: A nationwide socioacoustic survey in Japan

    Directory of Open Access Journals (Sweden)

    Takayuki Kageyama

    2016-01-01

    Full Text Available The association of wind turbine noise (WTN with sleep and physical/mental health has not been fully investigated. To investigate the relationship of WTN with the prevalence of self-reported symptoms of sleep and health problems, a socioacoustic survey of 1079 adult residents was conducted throughout Japan (2010-2012: 747 in 34 areas surrounding wind turbine plants and 332 in 16 control areas. During face-to-face interviews, the respondents were not informed of the purpose of the survey. Questions on symptoms such as sleeplessness and physical/mental complaints were asked without specifying reasons. Insomnia was defined as having one or any combination of the following that occurs three or more times a week and bothers a respondent: Difficulty initiating sleep, difficulty maintaining sleep, premature morning awakening, and feeling of light overnight sleep. Poor health was defined as having high scores for health complaints, as determined using the Total Health Index, exceeding the criteria proposed by the authors of the index. The noise descriptor for WTN was LAeq,n outdoor, estimated from the results of actual measurement at some locations in each site. Multiple logistic analysis was applied to the LAeq,n and insomnia or poor health. The odds ratio (OR of insomnia was significantly higher when the noise exposure level exceeded 40 dB, whereas the self-reported sensitivity to noise and visual annoyance with wind turbines were also independently associated with insomnia. OR of poor health was not significant for noise exposure, but significant for noise sensitivity and visual annoyance. The above two moderators appear to indicate the features of respondents who are sensitive to stimuli or changes in their homeostasis.

  19. Exposure-response relationship of wind turbine noise with self-reported symptoms of sleep and health problems: A nationwide socioacoustic survey in Japan.

    Science.gov (United States)

    Kageyama, Takayuki; Yano, Takashi; Kuwano, Sonoko; Sueoka, Shinichi; Tachibana, Hideki

    2016-01-01

    The association of wind turbine noise (WTN) with sleep and physical/mental health has not been fully investigated. To investigate the relationship of WTN with the prevalence of self-reported symptoms of sleep and health problems, a socioacoustic survey of 1079 adult residents was conducted throughout Japan (2010-2012): 747 in 34 areas surrounding wind turbine plants and 332 in 16 control areas. During face-to-face interviews, the respondents were not informed of the purpose of the survey. Questions on symptoms such as sleeplessness and physical/mental complaints were asked without specifying reasons. Insomnia was defined as having one or any combination of the following that occurs three or more times a week and bothers a respondent: Difficulty initiating sleep, difficulty maintaining sleep, premature morning awakening, and feeling of light overnight sleep. Poor health was defined as having high scores for health complaints, as determined using the Total Health Index, exceeding the criteria proposed by the authors of the index. The noise descriptor for WTN was LAeq,n outdoor, estimated from the results of actual measurement at some locations in each site. Multiple logistic analysis was applied to the LAeq,n and insomnia or poor health. The odds ratio (OR) of insomnia was significantly higher when the noise exposure level exceeded 40 dB, whereas the self-reported sensitivity to noise and visual annoyance with wind turbines were also independently associated with insomnia. OR of poor health was not significant for noise exposure, but significant for noise sensitivity and visual annoyance. The above two moderators appear to indicate the features of respondents who are sensitive to stimuli or changes in their homeostasis.

  20. Diminished metabolic responses to centrally-administered apelin-13 in diet-induced obese rats fed a high-fat diet.

    Science.gov (United States)

    Clarke, K J; Whitaker, K W; Reyes, T M

    2009-02-01

    The central administration of apelin, a recently identified adipokine, has been shown to affect food and water intake. The present study investigated whether body weight could affect an animal's response to apelin. The effects of centrally-administered apelin-13 on food and water intake, activity and metabolic rate were investigated in adult male diet-induced obese (DIO) rats fed either a high fat (32%) or control diet. Rats were administered i.c.v. apelin-13, 15-30 min prior to lights out, and food and water intake, activity and metabolic rate were assessed. Intracerebroventricular administration of apelin-13 decreased food and water intake and respiratory exchange ratio in DIO rats on the control diet, but had no effect in DIO rats on the high-fat diet. In an effort to identify potential central mechanisms explaining the observed physiological responses, the mRNA level of the apelin receptor, APJ, was examined in the hypothalamus. A high-fat diet induced an up-regulation of the expression of the receptor. Apelin induced a down-regulation of the receptor, but only in the DIO animals on the high-fat diet. In conclusion, we have demonstrated a diminished central nervous system response to apelin that is coincident with obesity.

  1. Control of radiation sources in Japan

    International Nuclear Information System (INIS)

    Maki, S.

    2001-01-01

    The report refers to the regulations for radioactive material in force in Japan, and to the organizations with responsibilities for regulating radiation sources. An outline of the law regulating the use of radiation sources and radioactive materials is provided, including its scope, types of radiation sources under control, exemptions and the system of notification, authorization and inspection. The experience of Japan with orphan sources is presented in three different cases, and the measures carried out to store the orphan sources in safe conditions. (author)

  2. Japan's nuclear juggernaut

    International Nuclear Information System (INIS)

    Richner, S.

    1984-01-01

    A summary of nuclear energy in Japan is presented. Nuclear energy provides 17% of Japan's electricity but could provide much more. 25 more reactors (to add to the existing 27) are planned by 1995. The cooperation between Japanese government and industry and the economic assistance in building new plants means that these are not likely to be cancelled. Public acceptance of new plants has often been obtained by large cash employment inducements. Now, however, there is growing disillusionment when short-term well paid employment building the reactors is followed by unemployment when the reactor is in operation. Also there is a growing opposition to the storage of the nuclear waste. To maintain the growth of its nuclear industry Japan needs to export to provide a steady flow of big orders. (U.K.)

  3. Japan's advanced medicine.

    Science.gov (United States)

    Sho, Ri; Narimatsu, Hiroto; Murakami, Masayasu

    2013-10-01

    Like health care systems in other developed countries, Japan's health care system faces significant challenges due to aging of the population and economic stagnation. Advanced medicine (Senshin Iryou) is a unique system of medical care in Japan offering highly technology-driven medical care that is not covered by public health insurance. Advanced medicine has recently developed and expanded as part of health care reform. Will it work? To answer this question, we briefly trace the historical development of advanced medicine and describe the characteristics and current state of advanced medical care in Japan. We then offer our opinions on the future of advanced medicine with careful consideration of its pros and cons. We believe that developing advanced medicine is an attempt to bring health care reform in line rather than the goal of health care reform.

  4. The internationalization of Japan

    International Nuclear Information System (INIS)

    Kuroki, T.E.

    1989-01-01

    There are growing tensions and frictions between the U.S. and Japan. Among them are science and technology issues that relate to the development of superconductor technology, as well as economic, trade and agricultural issues. The structure of this friction is very complex. There are many interconnected issues that cannot be resolved one by one. This article focuses on the relationship between the U.S. and Japan. Some of the complexities behind the issues are discussed by defining different notions of internationalization and by presenting the positive and negative aspects of the Japanese approach that affects the future cooperation and competition between our nations in the area of superconductivity

  5. Divorce in contemporary Japan.

    Science.gov (United States)

    Fukurai, H; Alston, J

    1990-10-01

    Data from the 1985-86 Japanese census are analysed to explore the determinants of the divorce rates in Japan's forty-seven prefectures, using two theoretical models: (a) the social integration model, which is shown to have a greater utility in predicting Japanese divorce levels than (b), the human capital model. Female emigration patterns play a significant role in affecting the divorce rate. Population increase and net household income are also important predictors of the Japanese divorce rate and urbanization has a great influence in modern Japan. Demographic and aggregate variables such as migration, urbanization, and socioeconomic factors are useful when organized under a social integration model.

  6. Current trends in rehabilitation engineering in Japan.

    Science.gov (United States)

    Ohnabe, Hisaichi

    2006-01-01

    In 2005, the elderly generation comprised 20% of the Japanese population. This percentage will grow to approximately 30% in 2030, meaning that nearly one in three people in Japan will be 65 years of age or older. Japan is the first nation in the world to face this situation. This article uses the context of Japanese society to give an overview of the elderly and people with disabilities; the International Classification of Functioning, Disability, and Health model; rehabilitation engineering-related policy; and education. In addition, we examine how governmental programs and Japanese law regarding technical aids may evolve by 2030. Partner robots, intelligent powered wheelchairs, nursing robots, and other technologies are introduced as examples of rehabilitation engineering and assistive technology. We also discuss the volunteer activities of the Rehabilitation Engineering Society of Japan (RESJA) in response to the Asian tsunami disaster and the achievements of a group of students from a Japanese senior high school of industry.

  7. Response of understory vegetation over 10 years after thinning in an old-growth cedar and cypress plantation overgrazed by sika deer in eastern Japan

    Directory of Open Access Journals (Sweden)

    Atsushi Tamura

    2017-01-01

    Full Text Available Background Forest management strategies such as thinning have long been used to enhance ecosystem functions, especially in plantations. Thinning in plantations with high deer density, however, may not yield a desired increase in understory vegetation because deer graze on germinating plants after thinning. Here, we examine the changes in understory vegetation after thinning in plantations that have been overgrazed by sika deer to provide insight into the effects of thinning on ecosystem functions such as soil conservation and biological diversity. Methods We conducted our survey in the Tanzawa Mountains of eastern Japan. We surveyed the change in understory vegetation within and outside of three deer exclosures on a single slope with three levels of understory vegetation cover: sparse (1%, exclosure “US”, moderate (30%, exclosure “MM”, and dense (80%, exclosure “LD” over 10 years after a 30% thinning of an old-growth cedar and cypress plantation which was overgrazed by sika deer. Results Understory vegetation cover, biomass and species richness increased within and outside the “US” and “MM” exclosures after thinning, and biomass was greater within than outside the exclosures at 10 years after thinning. Unpalatable species dominated both “US” and “MM” exclosures before thinning, and trees and shrubs dominated within the exclosures over time after thinning. In contrast, unpalatable, grazing-tolerant, perennial, and annual species increased outside the “US” and “MM” exclosures. No noticeable changes were observed within and outside the “LD” exclosure when compared with the “US” and “MM” exclosures. Conclusions Our results suggest that thinning a stand by 30% based on volume resulted in an increase in understory vegetation cover mainly composed of both unpalatable and grazing-tolerant species in a plantation forest where understory vegetation is sparse or moderate and sika deer density is high. We

  8. Public information activities in Japan

    International Nuclear Information System (INIS)

    Ijima, Kazunori

    1998-01-01

    This is a slide presentation dealing with the public information (PI) activities in Japan. At present in Japan 51 nuclear power plants are in commercial operation contributing with a capacity of about 440 G We, i.e. 1/3 of the total electricity is produced by nuclear power. An investigation conducted by Advisory Committee for Energy resulted in the following guidelines in the advancing the Nuclear Power Policy: - maintain transparency in determining policy and reflect the voice of people, making information available to the public; - promote mutual understanding between areas that produce electricity by nuclear power and those that consume electricity; - cultivate an awareness of energy issues amongst the public to encourage them to take issues regarding Japan's energy policy to heart. Concerning the current PI, the following actions are undertaken at a nationwide scale: - for all people, supplying information by mass media, internet and holding lecture meetings and panel discussions etc; - for women, advertisements in journals; - for youth, educational materials, exhibition of energy etc; - for teachers, seminars; for opinion leaders, sending newsletters on nuclear energy. In areas for planned or constructed nuclear plants the PI actions are addressed to all people, women, fishermen, farmers and opinion leaders. There are given the responses to the following three questions addressed to the public concerning the nuclear power: - do you think whether we need nuclear power plants? - do you think whether nuclear power plants are safe? - what mechanism do you think generates energy during the production of nuclear power. A discussion of the results is presented. As future objectives of PI activities the following are in view: to cultivate reliability, to aware of information about nuclear power, to promote awareness of nuclear power, to promote mutual understanding of nuclear power. In conclusion, the need is stressed to make the PI activities more effective, to find

  9. Liquid hydrogen in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Yasumi, S. [Iwatani Corp., Osaka (Japan). Dept. of Overseas Business Development

    2009-07-01

    Japan's Iwatani Corporation has focused its attention on hydrogen as the ultimate energy source in future. Unlike the United States, hydrogen use and delivery in liquid form is extremely limited in the European Union and in Japan. Iwatani Corporation broke through industry stereotypes by creating and building Hydro Edge Co. Ltd., Japan's largest liquid hydrogen plant. It was established in 2006 as a joint venture between Iwatani and Kansai Electric Power Group in Osaka. Hydro Edge is Japan's first combined liquid hydrogen and ASU plant, and is fully operational. Liquid oxygen, liquid nitrogen and liquid argon are separated from air using the cryogenic energy of liquefied natural gas fuel that is used for power generation. Liquid hydrogen is produced efficiently and simultaneously using liquid nitrogen. Approximately 12 times as much hydrogen in liquid form can be transported and supplied as pressurized hydrogen gas. This technology is a significant step forward in the dissemination and expansion of hydrogen in a hydrogen-based economy.

  10. Language Testing in Japan.

    Science.gov (United States)

    Brown, James Dean, Ed.; Yamashita, Sayoko Okada, Ed.

    Papers on second language testing in Japan include: "Differences Between Norm-Referenced and Criterion-Referenced Tests" (James Dean Brown); "Criterion-Referenced Test Construction and Evaluation" (Dale T. Griffe); "Behavioral Learning Objectives as an Evaluation Tool" (Judith A. Johnson); "Developing Norm-…

  11. Dutch surgery in Japan

    NARCIS (Netherlands)

    van Gulik, Thomas M.; Nimura, Yuji

    2005-01-01

    An isolation policy was adopted in feudal Japan from 1639 to 1853 owing to the fear of foreign influence. During those 200 years of isolation, all foreigners were withheld from the country with the exception of the Dutch, who were permitted to establish a trading post on a small island in the Bay of

  12. Globalization in Japan

    DEFF Research Database (Denmark)

    Roesgaard, Marie Højlund

    2014-01-01

    Abstract for Nichibunken Copenhagen Symposium August 2012 Globalization in Japan – the case of moral education. 日本とグローバル化 - 道徳教育の件 Marie H. Roesgaard, Department of Cross-Cultural and Regional Studies, University of Copenhagen. This paper attempts to trace the history of global influence on Japan......Abstract for Nichibunken Copenhagen Symposium August 2012 Globalization in Japan – the case of moral education. 日本とグローバル化 - 道徳教育の件 Marie H. Roesgaard, Department of Cross-Cultural and Regional Studies, University of Copenhagen. This paper attempts to trace the history of global influence...... adjusting to those of the global currents that cannot be ignored. Further, I would suggest that global, or at least Western, influence is not a new thing in regard to moral education in Japan. The paper will provide an historical overview of the development of moral education since Meiji times and focus...

  13. China, South Korea, Japan

    International Nuclear Information System (INIS)

    Anon.

    1988-01-01

    Intended for Canadian readers, this popular account was suggested by the Sixth Pacific Basin Nuclear Conference. Economic, political, geographic, sociological and historical aspects of the nuclear programmes of China, South Korea and Japan are discussed. The importance of past, present and future Canadian nuclear trade with the area is indicated

  14. Japan's electronic packaging technologies

    Science.gov (United States)

    Tummala, Rao R.; Pecht, Michael

    1995-02-01

    The JTEC panel found Japan to have significant leadership over the United States in the strategic area of electronic packaging. Many technologies and products once considered the 'heart and soul' of U.S. industry have been lost over the past decades to Japan and other Asian countries. The loss of consumer electronics technologies and products is the most notable of these losses, because electronics is the United States' largest employment sector and is critical for growth businesses in consumer products, computers, automobiles, aerospace, and telecommunications. In the past there was a distinction between consumer and industrial product technologies. While Japan concentrated on the consumer market, the United States dominated the industrial sector. No such distinction is anticipated in the future; the consumer-oriented technologies Japan has dominated are expected to characterize both domains. The future of U.S. competitiveness will, therefore, depend on the ability of the United States to rebuild its technological capabilities in the area of portable electronic packaging.

  15. Japan's plutonium economy

    International Nuclear Information System (INIS)

    Hecht, M.M.

    1994-01-01

    Japan's plutonium economy is based on the most efficient use of nuclear energy, as envisioned under the Atoms for Peace program of the 1950s and 1960s. The nuclear pioneers assumed that all nations would want to take full advantage of atomic energy, recycling waste into new fuel to derive as much energy as possible from this resource

  16. Central Solenoid Insert Technical Specification

    Energy Technology Data Exchange (ETDEWEB)

    Martovetsky, Nicolai N [ORNL; Smirnov, Alexandre [ORNL

    2011-09-01

    The US ITER Project Office (USIPO) is responsible for the ITER central solenoid (CS) contribution to the ITER project. The Central Solenoid Insert (CSI) project will allow ITER validation the appropriate lengths of the conductors to be used in the full-scale CS coils under relevant conditions. The ITER Program plans to build and test a CSI to verify the performance of the CS conductor. The CSI is a one-layer solenoid with an inner diameter of 1.48 m and a height of 4.45 m between electric terminal ends. The coil weight with the terminals is approximately 820 kg without insulation. The major goal of the CSI is to measure the temperature margin of the CS under the ITER direct current (DC) operating conditions, including determining sensitivity to load cycles. Performance of the joints, ramp rate sensitivity, and stability against thermal or electromagnetic disturbances, electrical insulation, losses, and instrumentation are addressed separately and therefore are not major goals in this project. However, losses and joint performance will be tested during the CSI testing campaign. The USIPO will build the CSI that will be tested at the Central Solenoid Model Coil (CSMC) Test Facility at the Japan Atomic Energy Agency (JAEA), Naka, Japan. The industrial vendors (the Suppliers) will report to the USIPO (the Company). All approvals to proceed will be issued by the Company, which in some cases, as specified in this document, will also require the approval of the ITER Organization. Responsibilities and obligations will be covered by respective contracts between the USIPO, called Company interchangeably, and the industrial Prime Contractors, called Suppliers. Different stages of work may be performed by more than one Prime Contractor, as described in this specification. Technical requirements of the contract between the Company and the Prime Contractor will be covered by the Fabrication Specifications developed by the Prime Contractor based on this document and approved by

  17. Responsible Investing in the Asia-Pacific Region: Understanding Sustainability and Investments in Japan and Hong Kong/China in an Era of Global Climate and Environmental Change

    NARCIS (Netherlands)

    J. Park (Jacob)

    2014-01-01

    markdownabstract__Abstract__ The author of this thesis examined the concept and market development of responsible investing (RI), which can be defined as an investment process that integrates social and environmental considerations within the context of traditional investment processes. RI has

  18. Nuclear power development in Japan

    International Nuclear Information System (INIS)

    Sugawara, A.

    1994-01-01

    Energy situation in Japan and Japan's strategy for stable supply of energy are discussed. Benefits of nuclear power in comparison with other energy sources is considered. History of nuclear power development in Japan, modern status and future trends are described. 6 figs

  19. Summer cooling in the east central Arabian Sea - a process of dynamic response to the southwest monsoon

    Digital Repository Service at National Institute of Oceanography (India)

    RameshBabu, V.; Sastry, J.S.

    The cooling of the east central Arabian Sea during summer monsoon season is examined using data sets of MONEX '79 and MONSOON '77 programmes. These studies have revealed that downward transfer of heat due to the mixing of warm surface and cold sub...

  20. Retreating or standing: Responses of forest species and steppe species to climate change in arid eastern central Asia

    Science.gov (United States)

    Hong-Xiang Zhang; Ming-Li Zhang; Stewart C. Sanderson

    2013-01-01

    The temperature in arid Eastern Central Asia is projected to increase in the future, accompanied by increased variability of precipitation. To investigate the impacts of climate change on plant species in this area, we selected two widespread species as candidates, Clematis sibirica and C. songorica, from montane coniferous forest and arid steppe habitats respectively...

  1. Forced Migration and Global Responsibility for Health Comment on "Defining and Acting on Global Health: The Case of Japan and the Refugee Crisis".

    Science.gov (United States)

    Bozorgmehr, Kayvan; Razum, Oliver

    2016-11-05

    Forced migration has become a world-wide phenomenon in the past century, affecting increasing numbers of countries and people. It entails important challenges from a global health perspective. Leppold et al have critically discussed the Japanese interpretation of global responsibility for health in the context of forced migration. This commentary complements their analysis by outlining three priority areas of global health responsibility for European Union (EU) countries. We highlight important stages of the migration phases related to forced migration and propose three arguments. First, the chronic neglect of the large number of internally displaced persons (IDPs) in the discourses on the "refugee crisis" needs to be corrected in order to develop sustainable solutions with a framework of the Sustainable Development Goals (SDGs). Second, protection gaps in the global system of protection need to be effectively closed to resolve conflicts with border management and normative global health frameworks. Third, effective policies need to be developed and implemented to meet the health and humanitarian needs of forced migrants; at the same time, the solidarity crisis within the EU needs to be overcome. These stakes are high. EU countries, being committed to global health, should urgently address these areas. © 2017 The Author(s); Published by Kerman University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

  2. Forced Migration and Global Responsibility for Health; Comment on “Defining and Acting on Global Health: The Case of Japan and the Refugee Crisis”

    Directory of Open Access Journals (Sweden)

    Kayvan Bozorgmehr

    2017-07-01

    Full Text Available Forced migration has become a world-wide phenomenon in the past century, affecting increasing numbers of countries and people. It entails important challenges from a global health perspective. Leppold et al have critically discussed the Japanese interpretation of global responsibility for health in the context of forced migration. This commentary complements their analysis by outlining three priority areas of global health responsibility for European Union (EU countries. We highlight important stages of the migration phases related to forced migration and propose three arguments. First, the chronic neglect of the large number of internally displaced persons (IDPs in the discourses on the “refugee crisis” needs to be corrected in order to develop sustainable solutions with a framework of the Sustainable Development Goals (SDGs. Second, protection gaps in the global system of protection need to be effectively closed to resolve conflicts with border management and normative global health frameworks. Third, effective policies need to be developed and implemented to meet the health and humanitarian needs of forced migrants; at the same time, the solidarity crisis within the EU needs to be overcome. These stakes are high. EU countries, being committed to global health, should urgently address these areas.

  3. [Gambling disorder in Japan].

    Science.gov (United States)

    Tanabe, Hitoshi

    2015-09-01

    Gambling disorder is a psychiatric disorder characterized by persistent and recurrent problematic gambling behavior, associated with impaired functioning, reduced quality of life, and frequent divorce and bankruptcy. Gambling disorder is reclassified in the category Substance-Related and Addictive Disorders in the DSM-5 because its clinical features closely resemble those of substance use disorders, and gambling activates the reward system in brain in much the same way drugs do. Prevalence of gambling disorder in Japan is high rate because of slot machines and pachinko game are very popular in Japan. The author recommend group psychotherapy and self-help group (Gamblers Anonymous), because group dynamics make them accept their wrongdoings related to gambling and believe that they can enjoy their lives without gambling.

  4. Safeguards activities in Japan

    International Nuclear Information System (INIS)

    Osabe, Takeshi

    1998-01-01

    Current Japanese State System for Accountancy and Control (SSAC) has been developing and fully satisfies requirements of both IAEA Safeguards and bilateral partners. However, the public attention on the national and international safeguards activities were increased and the safeguards authorities were required to promote the objective assessment of safeguards implementation to avoid mistrust in safeguards activities which directly influence the public acceptance of nuclear energy in itself. Additionally, since Japan has promoted to complete nuclear fuel cycle including spent fuel reprocessing, enrichment and mixed oxide fuel fabrication this would require further assurance of Japanese non-proliferation commitment. Japan supports the introduction of strengthened safeguards. In this context it is particularly important to strengthen the relationship between national and the IAEA safeguards to contribute actively to the IAEA safeguards in development and utilization of new technologies towards more effective and efficient IAEA safeguards

  5. Immature intra-oceanic arc-type volcanism on the Izanagi Plate revealed by the geochemistry of the Daimaruyama greenstones in the Hiroo Complex, southern Hidaka Belt, central Hokkaido, Japan

    Science.gov (United States)

    Yamasaki, Toru; Nanayama, Futoshi

    2018-03-01

    The Izanagi Plate is assumed to have underlain the western Panthalassa Ocean to the east of Eurasia, and to have been subducting under the Eurasian continent. Although the Izanagi Plate has been lost to subduction, the subduction complexes of the circum-Panthalassa continental margins provide evidence that subduction-related volcanism occurred within the Panthalassa Ocean, and not just along its margins. The Daimaruyama mass is a kilometer-sized allochthonous greenstone body in the Hiroo Complex in the southeastern part of the Nakanogawa Group in the southern Hidaka Belt, northern Japan. The Hiroo Complex is a subduction complex that formed within the Paleo-Kuril arc-trench system at 57-48 Ma. The Daimaruyama greenstones consist mainly of coarse volcaniclastic rocks with lesser amount of lava. Red bedded chert, red shale, and micritic limestone are also observed as blocks associated with the greenstones. The presence of Early Cretaceous (Aptian-Albian) radiolaria in red bedded cherts within the greenstones indicates that the Daimaruyama greenstones formed after this time. An integrated major and trace element geochemical dataset for whole-rocks and clinopyroxenes of the greenstones indicates a calc-alkaline magmatic trend with low TiO2 contents and increases in SiO2 and decreases in FeO* with increasing differentiation. Negative anomalies of Nb, Ta, and Ti in normal mid-ocean-ridge basalt type normalized patterns are interpreted as "arc-signatures". Using "rhyolite-MELTS", we conducted a numerical simulation of magmatic differentiation under conditions of 1.5 kbar and H2O = 3 wt% to reproduce the liquid line of descent of the Daimaruyama greenstones. Back-calculations of the equilibrium melt compositions from the trace element chemistry of the clinopyroxenes generally agree with the whole-rock rare earth element compositions of the Daimaruyama greenstones, therefore providing support for the conditions used for the rhyolite-MELTS calculations as well as the actual

  6. Towards better understanding of the response of Sphagnum peatland to increased temperature and reduced precipitation in Central Europe

    Science.gov (United States)

    Juszczak, Radoslaw; Basińska, Anna; Chojnicki, Bogdan; Gąbka, Maciej; Hoffmann, Mathias; Józefczyk, Damian; Lamentowicz, Mariusz; Leśny, Jacek; Łuców, Dominika; Moni, Christophe; Reczuga, Monika; Samson, Mateusz; Silvennoinen, Hanna; Stróżecki, Marcin; Urbaniak, Marek; Zielińska, Małgorzata; Olejnik, Janusz

    2017-04-01

    temperature, methane emissions were positively correlated with LAI of vascular plants, which was higher at the warmer sites during both years. Despite of being a net sink for CO2 during both years, the NEE was five times smaller for all sites (-100 gCṡm-2yr-1) during the dry 2015 year compared to 2016. The highest CO2 emissions were measured for the site with increased temperature (W site, Reco 780 gCṡm-2yr-1). Temperature increase also provoked the productivity - GPP was the highest at W site. While the smallest CO2 emissions and GPP were recorded on the site exposed to reduced precipitation. This emphasizes the importance of drought in inhibiting respiration and carbon uptake by plants. Despite of a higher productivity, NEE was smaller on W and W+D, due to higher CO2 effluxes. As a result of the drier conditions in 2015, the GWP of all sites was positive, showing the highest values for the temperature increased sites. Compared to that, GWP was negative for all sites besides those exposed to drought during the more wet year 2016. Different vegetation parameters further support the C exchange estimates. In general, warmer and drier conditions led to an increased LAI, whilst the site only exposed to drought exhibited the lowest NDVI. In addition, increased temperatures shifted the vegetation species composition by promoting vascular plants (mainly Carex rostrata and C. limosa), which correlates positively with nutrient (Ptot, Mn, F, Na, Zn) availability in the ground water. We report short-term responses of peatland to increased temperature and reduced precipitation, showing that the combination of these to stressors are leading to very different scenarios, regardless of their individual impacts. Thus our results emphasize the need for long term records from full-factorial field manipulation sites on peatland response to climate changes. The Research was co-founded by the Polish National Centre for Research and Development within the Polish-Norwegian Research Programme

  7. Japan Accelerator Conference

    International Nuclear Information System (INIS)

    Anon.

    1989-01-01

    At the international level, the high energy accelerator scene evolves rapidly and the International Conference on High Energy Accelerators is where its strong pulse can best be felt. This year, the Conference was held for the first time in Japan, with the 14th meeting in the series having been hosted in August by the Japanese KEK National Laboratory for High Energy Physics, Tsukuba. The venue was a recognition of the premier accelerator physics and technology status achieved by this diligent nation

  8. Japan Accelerator Conference

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1989-11-15

    At the international level, the high energy accelerator scene evolves rapidly and the International Conference on High Energy Accelerators is where its strong pulse can best be felt. This year, the Conference was held for the first time in Japan, with the 14th meeting in the series having been hosted in August by the Japanese KEK National Laboratory for High Energy Physics, Tsukuba. The venue was a recognition of the premier accelerator physics and technology status achieved by this diligent nation.

  9. Nuclear situation in Japan

    International Nuclear Information System (INIS)

    2006-01-01

    This analysis takes stock on the nuclear situation in Japan. It discusses the ambitious equipment program in collaboration with the France, the destabilization of the japanese nuclear industry following the accidents and the energy policy evolutions. It presents the projects of the japanese nuclear industry: the Monju reactor restart, the Pluthermal project, the reprocessing power plant of Rokkasho Mura, the new reactors, the russian weapons dismantling, the ITER site selection and the buy out of Westinghouse by Toshiba. (A.L.B.)

  10. Japan's fuel recycling policy

    International Nuclear Information System (INIS)

    Anon.

    1991-01-01

    The Atomic Energy Commission (AEC) has formulated Japanese nuclear fuel recycling plan for the next 20 years, based on the idea that the supply and demand of plutonium should be balanced mainly through the utilization of plutonium for LWRs. The plan was approved by AEC, and is to be incorporated in the 'Long term program for development and utilization of nuclear energy' up for revision next year. The report on 'Nuclear fuel recycling in Japan' by the committee is characterized by Japanese nuclear fuel recycling plan and the supply-demand situation for plutonium, the principle of the possession of plutonium not more than the demand in conformity with nuclear nonproliferation attitude, and the establishment of a domestic fabrication system of uranium-plutonium mixed oxide fuel. The total plutonium supply up to 2010 is estimated to be about 85 t, on the other hand, the demand will be 80-90 t. The treatment of plutonium is the key to the recycling and utilization of nuclear fuel. By around 2000, the private sector will commercialize the fabrication of the MOX fuel for LWRs at the annual rate of about 100 t. Commitment to nuclear nonproliferation, future nuclear fuel recycling program in Japan, MOX fuel fabrication system in Japan and so on are reported. (K.I.)

  11. Psychology in Japan.

    Science.gov (United States)

    Imada, Hiroshi; Tanaka-Matsumi, Junko

    2016-06-01

    The purpose of this article is to provide information about Japan and its psychology in advance of the 31st International Congress of Psychology (ICP), to be held in Yokohama, Japan, in 2016. The article begins with the introduction of the Japanese Psychological Association (JPA), the hosting organization of the ICP 2016, and the Japanese Union of Psychological Associations consisting of 51 associations/societies, of which the JPA is a member. This is followed by a brief description of a history of psychology of Japan, with emphasis on the variation in our approach to psychology in three different periods, that is, the pre- and post-Pacific War periods, and the post-1960 period. Next, the international contributions of Japanese psychology/psychologists are discussed from the point of view of their visibility. Education and training in psychology in Japanese universities is discussed with a final positive remark about the long-awaited enactment of the Accredited Psychologist Law in September, 2015. © 2016 International Union of Psychological Science.

  12. Negative Energy Balance Blocks Neural and Behavioral Responses to Acute Stress by "Silencing" Central Glucagon-Like Peptide 1 Signaling in Rats.

    Science.gov (United States)

    Maniscalco, James W; Zheng, Huiyuan; Gordon, Patrick J; Rinaman, Linda

    2015-07-29

    Previous reports indicate that caloric restriction attenuates anxiety and other behavioral responses to acute stress, and blunts the ability of stress to increase anterior pituitary release of adrenocorticotropic hormone. Since hindbrain glucagon-like peptide-1 (GLP-1) neurons and noradrenergic prolactin-releasing peptide (PrRP) neurons participate in behavioral and endocrine stress responses, and are sensitive to the metabolic state, we examined whether overnight food deprivation blunts stress-induced recruitment of these neurons and their downstream hypothalamic and limbic forebrain targets. A single overnight fast reduced anxiety-like behavior assessed in the elevated-plus maze and acoustic startle test, including marked attenuation of light-enhanced startle. Acute stress [i.e., 30 min restraint (RES) or 5 min elevated platform exposure] robustly activated c-Fos in GLP-1 and PrRP neurons in fed rats, but not in fasted rats. Fasting also significantly blunted the ability of acute stress to activate c-Fos expression within the anterior ventrolateral bed nucleus of the stria terminalis (vlBST). Acute RES stress suppressed dark-onset food intake in rats that were fed ad libitum, whereas central infusion of a GLP-1 receptor antagonist blocked RES-induced hypophagia, and reduced the ability of RES to activate PrRP and anterior vlBST neurons in ad libitum-fed rats. Thus, an overnight fast "silences" GLP-1 and PrRP neurons, and reduces both anxiety-like and hypophagic responses to acute stress. The partial mimicking of these fasting-induced effects in ad libitum-fed rats after GLP-1 receptor antagonism suggests a potential mechanism by which short-term negative energy balance attenuates neuroendocrine and behavioral responses to acute stress. The results from this study reveal a potential central mechanism for the "metabolic tuning" of stress responsiveness. A single overnight fast, which markedly reduces anxiety-like behavior in rats, reduces or blocks the ability of

  13. Oak (Quercus spp.) response to climate differs more among sites than among species in central Czech Republic

    Czech Academy of Sciences Publication Activity Database

    Rybníček, Michal; Čermák, P.; Prokop, O.; Žid, T.; Trnka, Miroslav; Kolář, Tomáš

    2016-01-01

    Roč. 75, jan (2016), s. 55-65 ISSN 1641-1307 R&D Projects: GA MŠk(CZ) LO1415; GA MŠk(CZ) LD13030; GA MŠk(CZ) EE2.3.20.0265; GA ČR GA13-04291S Institutional support: RVO:67179843 Keywords : Central Europe * oak * precipitation * temperature * tree rings Subject RIV: EH - Ecology, Behaviour Impact factor: 0.776, year: 2016

  14. Growth hormone response to GRF 1-44 in children following cranial irradiation for central nervous system tumors

    International Nuclear Information System (INIS)

    Oberfield, S.E.; Kirkland, J.L.; Frantz, A.; Allen, J.C.; Levine, L.S.

    1987-01-01

    The growth hormone (GH) responses to (A) GRF 1-44, 1 microgram/kg i.v., (B) L-dopa and either arginine, insulin, or glucagon, and (C) exercise were evaluated in 10 children (3 girls, 7 boys; ages 10 years to 15 years, 8 months), 2-10.75 years following cranial irradiation for medulloblastoma (8 patients), pineoblastoma (1 patient), and a fourth ventricular ependymoma (1 patient). Nine of the 10 children had abnormal growth rates. All children were euthyroid at the time of the study. The mean 0-60-min peak GH response to GRF (10.06 +/- 2.6 ng/ml) in the patients was less than the mean peak GH response (29 +/- 2.3 ng/ml) in the control children (n = 7). In 6 patients (5 with poor growth rates), a decreased GH response was noted to GRF and all other tests. Of the remaining patients, all with poor growth rates, two patients demonstrated an adequate response to GRF and pharmacologic testing; one patient had a normal GH response to GRF with a low GH response to pharmacologic testing; and one patient had a low response to GRF, despite a normal response to both exercise and pharmacologic testing. The decrease in mean peak GH response to GRF in the patient population confirms that radiation to the hypothalamic-pituitary region produces abnormalities in growth hormone release. Furthermore, in these patients, discordant GH responses to GRF and pharmacologic or physiologic tests can be observed. The abnormality in growth hormone release may result from a hypothalamic dysfunction in GRF release and/or damage to GH secretory pituicytes

  15. Behavioural conditioning of immune functions: how the central nervous system controls peripheral immune responses by evoking associative learning processes.

    Science.gov (United States)

    Riether, Carsten; Doenlen, Raphaël; Pacheco-López, Gustavo; Niemi, Maj-Britt; Engler, Andrea; Engler, Harald; Schedlowski, Manfred

    2008-01-01

    During the last 30 years of psychoneuroimmunology research the intense bi-directional communication between the central nervous system (CNS) and the immune system has been demonstrated in studies on the interaction between the nervous-endocrine-immune systems. One of the most intriguing examples of such interaction is the capability of the CNS to associate an immune status with specific environmental stimuli. In this review, we systematically summarize experimental evidence demonstrating the behavioural conditioning of peripheral immune functions. In particular, we focus on the mechanisms underlying the behavioural conditioning process and provide a theoretical framework that indicates the potential feasibility of behaviourally conditioned immune changes in clinical situations.

  16. Central venous pressure and shock index predict lack of hemodynamic response to volume expansion in septic shock: a prospective, observational study.

    Science.gov (United States)

    Lanspa, Michael J; Brown, Samuel M; Hirshberg, Eliotte L; Jones, Jason P; Grissom, Colin K

    2012-12-01

    Volume expansion is a common therapeutic intervention in septic shock, although patient response to the intervention is difficult to predict. Central venous pressure (CVP) and shock index have been used independently to guide volume expansion, although their use is questionable. We hypothesize that a combination of these measurements will be useful. In a prospective, observational study, patients with early septic shock received 10-mL/kg volume expansion at their treating physician's discretion after brief initial resuscitation in the emergency department. Central venous pressure and shock index were measured before volume expansion interventions. Cardiac index was measured immediately before and after the volume expansion using transthoracic echocardiography. Hemodynamic response was defined as an increase in a cardiac index of 15% or greater. Thirty-four volume expansions were observed in 25 patients. A CVP of 8 mm Hg or greater and a shock index of 1 beat min(-1) mm Hg(-1) or less individually had a good negative predictive value (83% and 88%, respectively). Of 34 volume expansions, the combination of both a high CVP and a low shock index was extremely unlikely to elicit hemodynamic response (negative predictive value, 93%; P = .02). Volume expansion in patients with early septic shock with a CVP of 8 mm Hg or greater and a shock index of 1 beat min(-1) mm Hg(-1) or less is unlikely to lead to an increase in cardiac index. Copyright © 2012 Elsevier Inc. All rights reserved.

  17. Changes in the Phosphoproteome and Metabolome Link Early Signaling Events to Rearrangement of Photosynthesis and Central Metabolism in Salinity and Oxidative Stress Response in Arabidopsis.

    Science.gov (United States)

    Chen, Yanmei; Hoehenwarter, Wolfgang

    2015-12-01

    Salinity and oxidative stress are major factors affecting and limiting the productivity of agricultural crops. The molecular and biochemical processes governing the plant response to abiotic stress have often been researched in a reductionist manner. Here, we report a systemic approach combining metabolic labeling and phosphoproteomics to capture early signaling events with quantitative metabolome analysis and enzyme activity assays to determine the effects of salt and oxidative stress on plant physiology. K(+) and Na(+) transporters showed coordinated changes in their phosphorylation pattern, indicating the importance of dynamic ion homeostasis for adaptation to salt stress. Unique phosphorylation sites were found for Arabidopsis (Arabidopsis thaliana) SNF1 kinase homolog10 and 11, indicating their central roles in the stress-regulated responses. Seven Sucrose Non-fermenting1-Related Protein Kinase2 kinases showed varying levels of phosphorylation at multiple serine/threonine residues in their kinase domain upon stress, showing temporally distinct modulation of the various isoforms. Salinity and oxidative stress also lead to changes in protein phosphorylation of proteins central to photosynthesis, in particular the kinase State Transition Protein7 required for state transition and light-harvesting II complex proteins. Furthermore, stress-induced changes of the phosphorylation of enzymes of central metabolism were observed. The phosphorylation patterns of these proteins were concurrent with changes in enzyme activity. This was reflected by altered levels of metabolites, such as the sugars sucrose and fructose, glycolysis intermediates, and amino acids. Together, our study provides evidence for a link between early signaling in the salt and oxidative stress response that regulates the state transition of photosynthesis and the rearrangement of primary metabolism. © 2015 American Society of Plant Biologists. All Rights Reserved.

  18. Skiing research in Japan.

    Science.gov (United States)

    Watanabe, K

    1981-01-01

    Skiing and skiing techniques were introduced by the Austrians to Japanese soldiers in 1911. After that, skiing spread beyond the original purpose and recently produced the ski sciences. From a sports biomechanical aspect, the development of the study of ski jumping, alpine skiing, and the basic movement in skiing is introduced in this paper. One of the characteristic points of these studies in Japan was that the ski sciences were supported not only by biomechanists and physiologists, but also basically by physicists and engineers. The fundamental research and studies from divergent fields are supporting each other and being integrated into ski science.

  19. Nuclear services for Japan

    International Nuclear Information System (INIS)

    Anderson, B.

    1991-01-01

    The UK Atomic Energy Authority (UKAEA) became AEA Technology in April 1990. The commercial interests are focussed through 4 business units: AEA Reactor Services, with whom several contracts have been won from Japanese customers for high resolution Field Emission Gun Scanning Transmission Electron Microscopy (FEGSTEM); AEA Fuel Services, a contract is being negotiated with an existing Japanese customer; AEA Decommissioning and Radwaste, with whom further development of an alternative approach to evaporation of liquid waste effluent for specific application in Japan is in progress; AEA Fusion. 1 fig

  20. Nyheder i Japan

    DEFF Research Database (Denmark)

    Sejrup, Jens

    2016-01-01

    Kan man stole på, hvad folk siger, når man ikke ved, hvem de er? Forholdet mellem kildeanonymitet og troværdighed er forskelligt i mediesystemer rundt om i verden. Troværdighed er ingen universel størrelse, men en retorisk effekt der opstår på baggrund af faktorer som er kulturelt og systemisk in...... indlejret. I Japan har seriøse nyhedsmedier et specielt forhold til udsagn fra anonyme kilder, og udstrakt brug af uidentificerede informanter står ikke i modsætning til journalistisk kvalitet og pålidelighed....

  1. Japan country report

    Energy Technology Data Exchange (ETDEWEB)

    Morisaki, Rieko [Energy Communication Planning, 3-9-16 Aobadai, 818-0137 Dazaifu (Japan)

    2008-07-01

    1. Nuclear 2007 highlights: - A magnitude 6.8 earthquake occurred in Niigata on July 16 2007. Owing to this earthquake, 3 units operating and 1 unit during start-up were shutdown automatically at TEPCO's Kashiwazaki-Kariwa NPS. Now, all 7 units of the NPS are in an outage for investigation. This influenced the capacity factor of Japanese NPPs in FY 2007, which stood at just 60.7%. - Debate on global warming is more and more active in Japan, as it is the host country of the G8 Hokkaido Toyako Summit in July. The Japan Atomic Energy Commission released 'White Paper on Nuclear Energy 2007' in March 2008. In the paper, they first expressed the view that the expansion of the peaceful use of nuclear energy is indispensable. 2. Nuclear overview: a. Energy policy: Electricity share: 25.4% of nuclear. The energy policy of Japan aims at nuclear power generation being maintained at the current level (30 to 40% of the total electricity generation) or increasing even after 2030, for stable energy supply and as a countermeasure against global warming. - Nuclear Fuel Cycle: The active tests at the JNFL reprocessing plant in Rokkasho-mura are in the final phase for commercial operation in 2008. By FY 2010 Plutonium utilization in LWRs in 16 to 18 NPP units. Around FY 2010 Installment of new centrifuges at the uranium enrichment plant at Rokkasho-mura. In FY 2012 Start of commercial operation of MOX fuel fabrication plant. Fast-breeder reactor cycle: Operation of the prototype reactor 'MONJU' has been suspended since a secondary sodium leak in 1995. JAEA (Japan Atomic Energy Agency) completed full-scale remodeling work and is implementing various tests to confirm the capabilities and soundness of MONJU. They aim to start its operation within FY 2008. Around 2025 Building a demonstration FBR. Before 2050 Development of a commercial FBR. - Electricity production (Operating): BWR: 32 units (including 4 units of APWR), PWR: 23 units. - Electricity production

  2. Positioning Indian Emigration to Japan

    DEFF Research Database (Denmark)

    D'Costa, Anthony

    2013-01-01

    as other IT-strong developing countries, are to supply technical talent, whose availability in Japan is constrained by the secular demographic crisis and changing educational and occupational preferences. The challenges for India are the institutional barriers, in particular, Japanese business practices...... that act as significant barriers to the entry of foreign skilled professionals. The paper brings out the source and pattern of foreign professionals and students in Japan as a proxy for talent. Though India’s presence in Japan is currently limited, its share of technical professionals to the total number....... For Japan, it means access to technical professionals and managed interfacing with the global economy....

  3. Investigating the dynamics of the brain response to music: A central role of the ventral striatum/nucleus accumbens.

    Science.gov (United States)

    Mueller, Karsten; Fritz, Thomas; Mildner, Toralf; Richter, Maxi; Schulze, Katrin; Lepsien, Jöran; Schroeter, Matthias L; Möller, Harald E

    2015-08-01

    Ventral striatal activity has been previously shown to correspond well to reward value mediated by music. Here, we investigate the dynamic brain response to music and manipulated counterparts using functional magnetic resonance imaging (fMRI). Counterparts of musical excerpts were produced by either manipulating the consonance/dissonance of the musical fragments or playing them backwards (or both). Results show a greater involvement of the ventral striatum/nucleus accumbens both when contrasting listening to music that is perceived as pleasant and listening to a manipulated version perceived as unpleasant (backward dissonant), as well as in a parametric analysis for increasing pleasantness. Notably, both analyses yielded a ventral striatal response that was strongest during an early phase of stimulus presentation. A hippocampal response to the musical stimuli was also observed, and was largely mediated by processing differences between listening to forward and backward music. This hippocampal involvement was again strongest during the early response to the music. Auditory cortex activity was more strongly evoked by the original (pleasant) music compared to its manipulated counterparts, but did not display a similar decline of activation over time as subcortical activity. These findings rather suggest that the ventral striatal/nucleus accumbens response during music listening is strongest in the first seconds and then declines. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Autoimmune central diabetes insipidus in a patient with ureaplasma urealyticum infection and review on new triggers of immune response.

    Science.gov (United States)

    Murdaca, Giuseppe; Russo, Rodolfo; Spanò, Francesca; Ferone, Diego; Albertelli, Manuela; Schenone, Angelo; Contatore, Miriam; Guastalla, Andrea; De Bellis, Annamaria; Garibotto, Giacomo; Puppo, Francesco

    2015-12-01

    Diabetes insipidus is a disease in which large volumes of dilute urine (polyuria) are excreted due to vasopressin (AVP) deficiency [central diabetes insipidus (CDI)] or to AVP resistance (nephrogenic diabetes insipidus). In the majority of patients, the occurrence of CDI is related to the destruction or degeneration of neurons of the hypothalamic supraoptic and paraventricular nuclei. The most common and well recognized causes include local inflammatory or autoimmune diseases, vascular disorders, Langerhans cell histiocytosis (LCH), sarcoidosis, tumors such as germinoma/craniopharyngioma or metastases, traumatic brain injuries, intracranial surgery, and midline cerebral and cranial malformations. Here we have the opportunity to describe an unusual case of female patient who developed autoimmune CDI following ureaplasma urealyticum infection and to review the literature on this uncommon feature. Moreover, we also discussed the potential mechanisms by which ureaplasma urealyticum might favor the development of autoimmune CDI.

  5. Strong congruence in tree and fern community turnover in response to soils and climate in central Panama

    DEFF Research Database (Denmark)

    Jones, Mirkka; Ferrier, Simon; Condit, Richard

    2013-01-01

    1. Plant species turnover in central Panamanian forests has been principally attributed to the effects of dispersal limitation and a strong Caribbean to Pacific gradient in rainfall seasonality. Despite marked geological heterogeneity, the role of soil variation has not been rigorously examined. 2....... We modelled the compositional turnover of trees and ferns in the Panama Canal watershed as a function of soil chemistry, climate and geographical separation, using generalized dissimilarity models (GDMs). 3. Predictability in both plant groups was strong, with 74% of turnover explained in trees...... and 49% in ferns. Major trends in the two plant groups were strikingly similar. The independent effects of soils, and of climate for trees, were sizeable, but those of geographical distance were minor. In both plant groups, distance and climatic effects on species turnover covaried strongly. 4. Including...

  6. Establishment of the Japan Atomic Energy Agency

    International Nuclear Information System (INIS)

    Okazaki, Toshio

    2006-01-01

    A goal of the 21. century is for society to pursue 'sustainable economic development and prosperous life by recycling resources', thus rejecting 'development based on the waste of resources'. For Japan, which has limited energy resources, it is important to secure safe, inexpensive, environmentally friendly energy resources having long-term availability. To contribute to long-term energy security and solve global environmental issues, and to create advanced competitive science and technology, the Japan Atomic Energy Agency (JAEA) was established by integrating the Japan Atomic Energy Research Institute (JAERI) and the Japan Nuclear Cycle Development Institute (JNC) in October 2005. JAEA is endeavoring to establish nuclear fuel cycles, to contribute to social improvement through hydrogen production initiated by atomic energy, and to pursue research and development of thermonuclear fusion and quantum beam technology. This paper reviews the main R and D activities of JAEA. The structure of the paper is the following: 1. Introduction; 2. Japan Atomic Energy Agency; 3. Efforts to Commercialize the Fast Reactor Cycle; 4. Monju Progress; 5. Geological Disposal of High-Level Radioactive Waste R and D; 6. High Temperature Gas-Cooled Reactor System R and D; 7. Fusion Research and Development; 8. LWR Spent Fuel Reprocessing Technology; 9. Quantum Beam Technologies; 10. Nuclear Safety Research and Regulatory Applications; 11. Basic Science and Engineering Research; 12. Contribution to the Enhanced International Nonproliferation Regimes; 13. Conclusions. To summarize, JAEA will promote the above R and D activities, addressing the following commitments: - On problems that atomic energy faces, we shall extend technical assistance in response to the government and the industrial sectors. - We shall produce technical options to attain political goals to secure medium to long-term stable energy supplies and to solve global environmental issues. - With the high potentials of atomic

  7. Comparison of two large earthquakes: the 2008 Sichuan Earthquake and the 2011 East Japan Earthquake.

    Science.gov (United States)

    Otani, Yuki; Ando, Takayuki; Atobe, Kaori; Haiden, Akina; Kao, Sheng-Yuan; Saito, Kohei; Shimanuki, Marie; Yoshimoto, Norifumi; Fukunaga, Koichi

    2012-01-01

    Between August 15th and 19th, 2011, eight 5th-year medical students from the Keio University School of Medicine had the opportunity to visit the Peking University School of Medicine and hold a discussion session titled "What is the most effective way to educate people for survival in an acute disaster situation (before the mental health care stage)?" During the session, we discussed the following six points: basic information regarding the Sichuan Earthquake and the East Japan Earthquake, differences in preparedness for earthquakes, government actions, acceptance of medical rescue teams, earthquake-induced secondary effects, and media restrictions. Although comparison of the two earthquakes was not simple, we concluded that three major points should be emphasized to facilitate the most effective course of disaster planning and action. First, all relevant agencies should formulate emergency plans and should supply information regarding the emergency to the general public and health professionals on a normal basis. Second, each citizen should be educated and trained in how to minimize the risks from earthquake-induced secondary effects. Finally, the central government should establish a single headquarters responsible for command, control, and coordination during a natural disaster emergency and should centralize all powers in this single authority. We hope this discussion may be of some use in future natural disasters in China, Japan, and worldwide.

  8. Near Real-Time Use of Optical Remote Sensing and Synthetic Aperture Radar for Response to Central U.S. Flooding in Late April-Early May 2017

    Science.gov (United States)

    Bell, J. R.; Schultz, L. A.; Jones, M.; Molthan, A.; Arko, S. A.; Hogenson, K.; Meyer, F. J.

    2017-12-01

    In late April and early May 2017, heavy rainfall across Missouri led to extensive flooding along the Missouri and Mississippi River basins in the Central United States. Determining the extent of flooding is critical for response organizations to properly deploy personnel and other assets involved in preparedness, mitigation, response, and recovery efforts. The Federal Emergency Management Agency (FEMA) relies on geospatial flood extent data, among other data, to estimate the impacts to population and infrastructure in order to prepare and engage response activities in support of the affected states and communities. To assist FEMA in mapping flood extent in a near real-time, the NASA Earth Science Disasters Program coordinates a multi-NASA center response to provide satellite imagery and products to FEMA during major flood events to supplement their analysis tools and capabilities. Scientists at the NASA Short-term Prediction Research and Transition (SPoRT) Center at Marshall Space Flight Center, who led this particular response, have been working with the Alaska Satellite Facility (ASF) at the University of Alaska Fairbanks to provide synthetic aperture radar (SAR) imagery and derived flood products to FEMA's geospatial response team in support of flooding events. Combined, these efforts helped to provide preliminary flood mapping to FEMA from a broad constellation of remote sensors. The presentation will describe the various products available throughout the response event, post-event collaborations examining these products in comparison to additional modeling and data collection by FEMA, training needs to improve product use, and more efficient methods for data delivery. Lessons learned will highlight opportunities for future work and improvement, and guide other ongoing efforts to develop collaborations that would also support other domestic emergency response activities, such as those led by the National Guard Bureau, which assists individual state Guard units.

  9. Tree-rings mirror management legacy: dramatic response of standard oaks to past coppicing in Central Europe.

    Directory of Open Access Journals (Sweden)

    Jan Altman

    Full Text Available BACKGROUND: Coppicing was one of the most important forest management systems in Europe documented in prehistory as well as in the Middle Ages. However, coppicing was gradually abandoned by the mid-20(th century, which has altered the ecosystem structure, diversity and function of coppice woods. METHODOLOGY/PRINCIPAL FINDINGS: Our aim was to disentangle factors shaping the historical growth dynamics of oak standards (i.e. mature trees growing through several coppice cycles in a former coppice-with-standards in Central Europe. Specifically, we tried to detect historical coppicing events from tree-rings of oak standards, to link coppicing events with the recruitment of mature oaks, and to determine the effects of neighbouring trees on the stem increment of oak standards. Large peaks in radial growth found for the periods 1895-1899 and 1935-1939 matched with historical records of coppice harvests. After coppicing, the number of newly recruited oak standards markedly grew in comparison with the preceding or following periods. The last significant recruitment of oak standards was after the 1930s following the last regular coppicing event. The diameter increment of oak standards from 1953 to 2003 was negatively correlated with competition indices, suggesting that neighbouring trees (mainly resprouting coppiced Tilia platyphyllos partly suppressed the growth of oak standards. Our results showed that improved light conditions following historical coppicing events caused significant increase in pulses of radial growth and most probably maintained oak recruitment. CONCLUSIONS/SIGNIFICANCE: Our historical perspective carries important implications for oak management in Central Europe and elsewhere. Relatively intense cutting creating open canopy woodlands, either as in the coppicing system or in the form of selective cutting, is needed to achieve significant radial growth in mature oaks. It is also critical for the successful regeneration and long

  10. Japan and atomic co-operation

    International Nuclear Information System (INIS)

    1965-01-01

    Japan, which is host country for the Ninth Regular Session of the Agency General Conference, has an important programme of nuclear power development to meet future needs. In addition, Japan is active in other applications of atomic energy and is building up a domestic nuclear engineering industry. Japan has profited by the Agency as a channel of international cooperation, and was a party to the first bilateral agreement in which the responsibility for administering safeguards against the diversion of materials to military purposes, was transferred to the Agency. Japan has also lent support to Agency programmes by gifts, training courses, research, and the loan of experts. In 1961, the Japan Atomic Energy Commission (AEC) formulated the 'Long-Range Programme for Development and Utilization of Atomic Energy', on the basis of the economic prospects of nuclear power generation, and the conditions necessary to meet the ever-increasing domestic energy demands. According to this programme, in the light of power reactor development trends overseas, it is expected that nuclear power costs will compete with those of oil burning stations by 1970. On this basis, total nuclear power generating capacity of 1000 MW(e) will be attained by 1970, and 7000 - 9 500M(e) by 1980. As a prelude to the above programme the Japan Atomic Power Company (JAPCO) began construction in 1959 of a graphite-moderated gas-cooled nuclear power station (Improved Calder Hall type) of 165 MW(e) gross capacity. This is now progressing smoothly, and reached criticality in May 1965; it is expected to supply commercial power by the end of this year. The second nuclear power station will be built by the same company on the coast of the Japan Sea, with a light water-moderated reactor of 250 - 300 MW(e) capacity. The construction plan i s currently being pushed forward for completion in 1970. Thereafter three private utility companies - Tokyo, Kansai and Chubu Electric Companies - are doing preparatory work for

  11. A remarkable sea-level drop and relevant biotic responses across the Guadalupian-Lopingian (Permian) boundary in low-latitude mid-Panthalassa: Irreversible changes recorded in accreted paleo-atoll limestones in Akasaka and Ishiyama, Japan

    Science.gov (United States)

    Kofukuda, Daisuke; Isozaki, Yukio; Igo, Hisayoshi

    2014-03-01

    The Capitanian (Upper Guadalupian) to Wuchiapingian (Lower Lopingian) shallow-marine limestones at Akasaka and Ishiyama in central Japan record unique aspects of the extinction-related Guadalupian-Lopingian boundary (G-LB) interval. The ca. 140 m-thick Akasaka Limestone consists of the Capitanian black limestone (Unit B; 112 m) and the Wuchiapingian light gray dolomitic limestone (Unit W; 21 m), with a black/white striped limestone (Unit S; 9 m) between them. The G-LB horizon is assigned at the base of Unit W, on the basis of the first occurrence of the Wuchiapingian fusulines. The Capitanian Unit B and the Wuchiapingian Unit W were deposited mostly in the subtidal zone of a lagoon, whereas the intervened Unit S and the lowermost Unit W were in the intertidal zone. A hiatus with a remarkable erosional feature was newly identified at the top of Unit S. These records indicate that the sea-level has dropped significantly around the G-LB to have exposed the top of the atoll complex above the sea-level. The Ishiyama Limestone, located ca. 10 km to the north of the Akasaka limestone, retains almost the same depositional records. The extinction of large-tested fusuline (Yabeina) and large bivalves (Alatoconchidae) occurred in the upper part of Unit B, and the overlying 20 m-thick limestone (the uppermost Unit B and Unit S) below the hiatus represents a unique barren interval. The upper half of the barren interval is more depleted in fossils than the lower half, and this likely represents a duration of the severest environmental stress(es) for the shallow-marine protists/animals on the mid-oceanic paleo-atoll complex. Small-tested fusulines re-appeared at the base of Unit W above the hiatus. These facts prove that the elimination of shallow-marine biota occurred during the Capitanian shallowing of Akasaka paleo-atoll before the subaerial exposure/erosion across the G-LB. The overall shallowing and the development of such a clear hiatus at the top of a mid-oceanic seamount

  12. Legalized abortion in Japan.

    Science.gov (United States)

    Hart, T M

    1967-10-01

    The enactment of the Eugenic Protection Act in Japan was followed by many changes. The population explosion was stemmed, the birth rate was halved, and while the marriage rate remained steady the divorce rate declined. The annual total of abortions increased until 1955 and then slowly declined. The highest incidence of abortions in families is in the 30 to 34 age group when there are four children in the family. As elsewhere abortion in advanced stages of pregnancy is associated with high morbidity and mortality. There is little consensus as to the number of criminal abortions. Reasons for criminal abortions can be found in the legal restrictions concerning abortion: Licensing of the abortionist, certification of hospitals, taxation of operations and the requirement that abortion be reported. Other factors are price competition and the patient's desire for secrecy. Contraception is relatively ineffective as a birth control method in Japan. Oral contraceptives are not yet government approved. In 1958 alone 1.1 per cent of married women were sterilized and the incidence of sterilization was increasing.

  13. Food irradiation in Japan

    International Nuclear Information System (INIS)

    Ito, Hitoshi

    1995-01-01

    The basic research on food irradiation in Japan was begun around 1955 by universities and national laboratories. In 1967, food irradiation was designated to the specific general research on atomic energy, and the national project on large scale was continued until 1983. As the result, the treatment of germination prevention for potatoes was approved by the Ministry of Health and Welfare in 1972. The Co-60 gamma ray irradiation facility of Shihoro Agricultural Cooperative is famous as the facility that succeeded in the practical use of food irradiation for the first time in the world. But the practical use of food irradiation stagnates and the research activities were reduced in Japan due to the circumstances thereafter. The effect of radiation to foods and living things is explained. The features of the radiation treatment of foods are small temperature rise, large transmissivity, no residue, the small loss of nutrition and large quantity, continuous treatment. The safety of irradiated foods is explained. The subjects for hereafter are discussed. (K.I.)

  14. Food Irradiation in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Kawabata, T.

    1981-09-15

    Since 1967 research activities on food irradiation in Japan have been carried out under the National Food Irradiation Programme by the Japanese Atomic Energy Commission. The programme has been concentrated on the technological and economical feasibility and wholesomeness testings of seven irradiated food items of economic importance to the country, i.e. potatoes, onions, wheat, rice, 'kamaboko' (fish-paste products), 'Vienna' sausages and mandarin oranges. By now most studies, including wholesomeness testings of these irradiated food items, have been completed. In Japan, all foods or food additives for sale are regulated by the Food Sanitation Law enforced in 1947. Based on studies made by the national programme, irradiated potatoes were given 'unconditional acceptance' for human consumption in 1972. At present, irradiated potatoes are the only food item which has so far been approved by the Minister of Health and Welfare. Unless the Minister of Health and Welfare has declared that items are not harmful to human health on obtaining comments from the Food Sanitation Investigation Council, no irradiated food can be processed or sold. In addition, the import of irradiated foodstuffs other than potatoes from foreign countries is prohibited by law.

  15. Physically-Based Modelling of the Post-Fire Runoff Response of a Forest Catchment in Central Portugal

    NARCIS (Netherlands)

    Eck, Van Christel M.; Nunes, Joao P.; Vieira, Diana C.S.; Keesstra, Saskia; Keizer, Jan Jacob

    2016-01-01

    Forest fires are a recurrent phenomenon in Mediterranean forests, with impacts for human landscapes and communities, which must be understood before they can be managed. This study used the physically based Limburg Soil Erosion Model (LISEM) to simulate rainfall–runoff response, under soil water

  16. Species-specific growth responses to climate variations in understory trees of a Central African rain forest

    NARCIS (Netherlands)

    Couralet, C.; Sterck, F.J.; Sass-Klaassen, U.; Acker, Van J.; Beekman, H.

    2010-01-01

    Basic knowledge of the relationships between tree growth and environmental variables is crucial for understanding forest dynamics and predicting vegetation responses to climate variations. Trees growing in tropical areas with a clear seasonality in rainfall often form annual growth rings. In the

  17. Interleukin-17 receptor A (IL-17RA) as a central regulator of the protective immune response against Giardia

    NARCIS (Netherlands)

    Paerewijck, O. (Oonagh); Maertens, B. (Brecht); L. Dreesen (Leentje); Van Meulder, F. (Frederik); Peelaers, I. (Iris); Ratman, D. (Dariusz); Li, R.W. (Robert W.); E.W. Lubberts (Erik); K. De Bosscher; P. Geldhof (Peter)

    2017-01-01

    textabstractThe protozoan parasite Giardia is a highly prevalent intestinal pathogen with a wide host range. Data obtained in mice, cattle and humans revealed the importance of IL-17A in the development of a protective immune response against Giardia. The aim of this study was to further unravel the

  18. Polyfunctional cytokine production by central memory T cells from cattle in response to Mycobacterium bovis infection and BCG vaccination

    Science.gov (United States)

    Polyfunctional T cells simultaneously produce IFN-gamma, IL-2 and TNF-alpha and play relevant roles in several chronic infections, including TB. Mycobacterium bovis infection of cattle elicits ex vivo polyfunctional T cell responses. Vaccine-elicited IFN-gamma Tcm (CD4 plus CD45RO plus CCR7 plus) re...

  19. Paleoseismic evidence of earthquakes and tsunamis along the southern part of the Japan Trench

    Science.gov (United States)

    Pilarczyk, Jessica; Sawai, Yuki; Horton, Ben; Namegaya, Yuichi; Shinozaki, Tetsuya; Tanigawa, Koichiro; Matsumoto, Dan; Dura, Tina; Fujiwara, Osamu; Shishikura, Masanobu

    2016-04-01

    The northern part of the Japan Trench has frequently generated tsunamigenic-earthquakes with magnitudes up to ~M 8.0. In contrast, the middle and southern parts of the Japan Trench were considered relatively inactive until the 2011 Tohoku (M 9.0) event generated one of the largest tsunamis in recorded history. Geologic evidence from the Sendai plain revealed an event in CE 869 that could have forecast the severity of the Tohoku tsunami in 2011. Seismic models indicate that the Tohoku earthquake may have transferred stress southwards down the fault to the potentially locked southern part of the Japan Trench. This transfer of stress towards a locked section of the trench could produce an earthquake in the near future that would be comparable in magnitude to the Tohoku event. Reconstructing the history of individual great earthquakes and accompanying tsunamis using geological records from the coastal zone adjacent to the southern part of the Japan Trench provides an assessment of the seismic hazard for metropolitan areas in east-central Japan. We have found two anomalous marine sand layers intercalated with muddy peat, which can be traced 3.8 km inland and 5.5 km along the present Kujukuri coastline, approximately 50 km east of Tokyo. Both sand layers have features consistent with tsunami deposits, such as a distinct erosional base, rip-up clasts, normal grading, a mud drape, and marine foraminifera. Results of radiocarbon dating constrain the age of the upper sand to 337 - 299 cal. yrs. BP, which likely corresponds to the only known southern Japan Trench rupture ever recorded, the Empo tsunami of CE 1677. The age of the lower sand is 979 - 903 cal. yrs. BP; marking an event for which there is no historical documentation at present. Preliminary tsunami simulation models indicate that a middle trench (Tohoku-style) rupture is not responsible for significant inundation of the Kujukuri coastline and would likely not have been capable of depositing either sand layer

  20. Response of the oxygen uptake efficiency slope to orthotopic heart transplantation: lack of correlation with changes in central hemodynamic parameters and resting lung function.

    Science.gov (United States)

    Van Laethem, Christophe; Goethals, Marc; Verstreken, Sofie; Walravens, Maarten; Wellens, Francis; De Proft, Margot; Bartunek, Jozef; Vanderheyden, Marc

    2007-09-01

    Recently, a new linear measure of ventilatory response to exercise, the oxygen uptake efficiency slope (OUES), was proposed in the evaluation of heart failure patients. No data are available on the response of the OUES after orthotopic heart transplantation (HTx). Thirty patients who underwent HTx between 1999 and 2003 were included in the study. Data from maximal cardiopulmonary exercise test, resting pulmonary function and hemodynamic assessment were collected before the transplant at time of screening and 1 year after HTx. During the first year after HTx, OUES and normalized OUES for body weight (OUES/kg) increased significantly from 15.6 +/- 4.9 to 19.7 +/- 4.8 (p volumes or capacities and measures of central hemodynamic function after HTx. OUES improved significantly after HTx, but, similar to other exercise parameters, remained considerably impaired. The changes in OUES were highly correlated with the improvements in other exercise variables, but did not correlate with marked improvements in central hemodynamics or resting lung function.

  1. Response surface methodology (RSM) modeling of microwave-assisted extraction of natural dye from Swietenia mahagony: A comparation between Box-Behnken and central composite design method

    Science.gov (United States)

    Kusuma, Heri Septya; Sudrajat, Robby Ginanjar Margo; Susanto, David Febrilliant; Gala, Selfina; Mahfud, Mahfud

    2015-12-01

    The increasing demand of non-toxic and environmentally friendly dyes, colorants that come from natural source have risen as an alternative of sintetic poisonous dyes. In this research natural dye from S. mahagony was extracted using microwave-assisted extraction method under different operating condition such as extraction time (10-30min), plant material to solvent ratio (0.03-0.05g/mL) and microwave power level (100-380 watt). Box-Behnken method and central composite design (CCD) method is widely used for modeling response surface methodology (RSM), both methods show good prediction performance. In this study response surface methodology was performed to optimize the process, both methods were performed by the help Statgraphics Centurion 16 to evaluate the effects of different operating parameters. Finally, both methods were statistically compared by root mean square error (RMSE) and absolute average deviation (AAD) based on validation data set. Further, result suggests that CCD has better performance as compared to Box-Behnken method. The maximum yield obtained for Box-Behnken is 3.7647% (380 watt, 0.0339g/mL, 28.8899min) and 3.7506% (379.986 watt, 0.0378g/mL, 30min) for central composite design method.

  2. Terrestrial lichen response to partial cutting in lodgepole pine forests on caribou winter range in west-central British Columbia

    Directory of Open Access Journals (Sweden)

    Michaela J. Waterhouse

    2011-09-01

    Full Text Available In west-central British Columbia, terrestrial lichens located in older, lodgepole pine (Pinus contorta forests are important winter forage for woodland caribou (Rangifer tarandus caribou. Clearcut harvesting effectively removes winter forage habitat for decades, so management approaches based on partial cutting were designed to maintain continuous lichen-bearing habitat for caribou. This study tested a group selection system, based on removal of 33% of the forest every 80 years in small openings (15 m diameter, and two irregular shelterwood treatments (whole-tree and stem-only harvesting methods where 50% of the stand area is cut every 70 years in 20 to 30 m diameter openings. The abundance of common terrestrial lichens among the partial cutting and no-harvest treatments was compared across five replicate blocks, pre-harvest (1995 and post-harvest (1998, 2000 and 2004. The initial loss of preferred forage lichens (Cladonia, Cladina, Cetraria and Stereocaulon was similar among harvesting treatments, but there was greater reduction in these lichens in the openings than in the residual forest. After eight years, forage lichens in the group selection treatment recovered to pre-harvest amounts, while lichen in the shelterwood treatments steadily increased from 49 to 57% in 1998 to about 70% of pre-harvest amounts in 2004. Although not part of the randomized block design, there was substantially less lichen in three adjacent clearcut blocks than in the partial cuts. Regression analysis pre- and post-harvest indicated that increased cover of trees, shrubs, herbs, woody debris and logging slash corresponded with decreased forage lichen abundance. In the short-term, forestry activities that minimize inputs of woody debris, control herb and shrub development, and moderate the changes in light and temperatures associated with canopy removal will lessen the impact on lichen. Implementation of stand level prescriptions is only one aspect of caribou habitat

  3. Activation of corticotropin-releasing factor receptors from the basolateral or central amygdala increases the tonic immobility response in guinea pigs: an innate fear behavior.

    Science.gov (United States)

    Donatti, Alberto Ferreira; Leite-Panissi, Christie Ramos Andrade

    2011-11-20

    The tonic immobility (TI) behavior is an innate response associated with extreme threat situations such as a predator attack. Several studies have provided evidence suggesting an important role for corticotropin-releasing factor (CRF) in the regulation of the endocrine system, defensive behaviors and behavioral responses to stress. TI has been shown to be positively correlated with the basal plasma levels of corticosterone. CRF receptors and neurons that are immunoreactive to CRF are found in many cerebral regions, especially in the amygdaloid complex. Previous reports have demonstrated the involvement of the basolateral amygdaloid (BLA) and central amygdaloid (CeA) nuclei in the TI response. In this study, we evaluated the CRF system of the BLA and the CeA in the modulation of the TI response in guinea pigs. The activation of CRF receptors in the BLA and in the CeA promoted an increase in the TI response. In contrast, the inhibition of these receptors via alpha-helical-CRF(9-41) decreased the duration of the TI response. Moreover, neither the activation nor inhibition of CRF receptors in the BLA or the CeA altered spontaneous motor activity in the open-field test. These data suggest that the activation of the CRF receptors in the BLA or the CeA probably potentiates fear and anxiety, which may be one of the factors that promote an increase in the TI behavior. Therefore, these data support the role of the CRF system in the control of emotional responses, particularly in the modulation of innate fear. Copyright © 2011 Elsevier B.V. All rights reserved.

  4. The central role of energy in Soddy's holistic and critical approach to nuclear science, economics, and social responsibility

    International Nuclear Information System (INIS)

    Trenn, T.J.

    1979-01-01

    The following aspects of Soddy's life and work are discussed: early work with Rutherford leading to the conviction that atoms contained an immense store of energy; his belief that this energy could be released and controlled for the benefit of mankind; his growing concern with the fundamental problems of social economics and the social responsibility of scientists; and his interest in economics and monetary reform. (U.K.)

  5. Ecophysiological responses to the effect of annual management on an endemic viviparous fish in central plateau of Mexico

    Directory of Open Access Journals (Sweden)

    Fernando Garcia-Trejo

    Full Text Available Studies on the biological aspects of fish typically focus on species that currently have commercial value, causing species that lack such market value to be ignored. This is the case of several freshwater fish, specifically of several members of the Goodeidae family. In the State of Querétaro there are several species of this family characterized for being viviparous and having distinctive sexual dimorphism that may have commercial potential. The subject of this study is Girardinichthys multiradiatus, a viviparous fish endemic to the upper-half of the Lerma River basin. The lack of knowledge regarding its biology and ecology has prevented the development of guidelines to manage its habitat and to preserve its population. The objective was to determine the ecophysiological responses of G. multiradiatus to its environmental management. From the sampling (24 hours every two months population structure and dynamics were analyzed throughout a hydrological cycle using meristic data (standard length. Trophic and ecophysiological responses to fluctuations in environmental factors were also identified. Although the mexcalpique is a polytrophic species, results show that it prefers feeding on Diptera or Cladocera, while detritus is the third substance frequently found in their stomachs. Environmentally, the water regime is responsible for fluctuations in the population dynamics of the species, while temperature changes are the most influence its energy balance. These results can guide efforts to conserve this species and its habitat.

  6. Barbarian medicine in feudal Japan.

    Science.gov (United States)

    Fodstad, Harald; Hariz, Marwan I; Hirabayashi, Hidehiro; Ohye, Chihiro

    2002-10-01

    THE FIRST EUROPEANS to discover Japan were Portuguese traders who arrived in 1542. Fifteen years later, the Portuguese Jesuit priest and surgeon Luis De Almeida (1525-1583) founded the first Western hospital in Japan, for the care of lepers, syphilitics, and orphans. Because the hospital had a negative influence on the spread of Christianity, the Jesuits closed it in 1586. During the Tokugawa Shogunate (1600-1868), when Japan was secluded from the rest of the world, the only foreign physicians allowed to enter Japan were those employed by the Dutch factory at Dejima in Nagasaki. Only four of those physicians left behind seeds for the foundation of Western medicine in Japan, namely Caspar Schambergen, who founded a Japanese school of surgery in 1650; Engelbert Kämpfer, who visited Japan in 1691 to 1692; Carl Peter Thunberg, who botanically explored Japan in 1775 to 1776; and Philipp Franz Balthasar von Siebold, who practiced medicine in Nagasaki in 1823 to 1829 and 1859 to 1861. On the whole, Western medicine and surgery never established a real foothold in Japan until the fall of the shogunate and the restoration of the emperor in 1868.

  7. Recent developments: Japan and Australia

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    Recent developments in the nuclear industry in Japan and Australia are briefly reviewed. Topics discussed include: the world energy situation; and nuclear power generation trends and completion the nuclear fuel cycle in Japan. Recent events that suggest possible policy changes in Australia are briefly discussed

  8. Community response of zooplankton to oceanographic changes (2002-2012) in the central/southern upwelling system of Chile

    Science.gov (United States)

    Medellín-Mora, Johanna; Escribano, Ruben; Schneider, Wolfgang

    2016-03-01

    A 10-year time series (2002-2012) at Station 18 off central/southern Chile allowed us to study variations in zooplankton along with interannual variability and trends in oceanographic conditions. We used an automated analysis program (ZooImage) to assess changes in the mesozooplankton size structure and the composition of the taxa throughout the entire community. Oceanographic conditions changed over the decade: the water column became less stratified, more saline, and colder; the mixed layer deepened; and the oxygen minimum zone became shallower during the second half of the time series (2008-2012) in comparison with the first period (2002-2007). Both the size structure and composition of the zooplankton were significantly associated with oceanographic changes. Taxonomic and size diversity of the zooplankton community increased to the more recent period. For the second period, small sized copepods (1.5 mm) and medium size copepods (1-1.5 mm), whereas euphausiids, decapod larvae, appendicularian and ostracods increased their abundance during the second period. These findings indicated that the zooplankton community structure in this eastern boundary ecosystem was strongly influenced by variability of the upwelling process. Thus, climate-induced forcing of upwelling trends can alter the zooplankton community in this highly productive region with potential consequences for the ecosystem food web.

  9. Response of the groundwater system in the Guanzhong Basin (central China) to climate change and human activities

    Science.gov (United States)

    Wang, Wenke; Zhang, Zaiyong; Duan, Lei; Wang, Zhoufeng; Zhao, Yaqian; Zhang, Qian; Dai, Meiling; Liu, Huizhong; Zheng, Xiaoyan; Sun, Yibo

    2018-03-01

    The Guanzhong Basin in central China features a booming economy and has suffered severe drought, resulting in serious groundwater depletion in the last 30 years. As a major water resource, groundwater plays a significant role in water supply. The combined impact of climate change and intensive human activities has caused a substantial decline in groundwater recharge and groundwater levels, as well as degradation of groundwater quality and associated changes in the ecosystems. Based on observational data, an integrated approach was used to assess the impact of climate change and human activities on the groundwater system and the base flow of the river basin. Methods included: river runoff records and a multivariate statistical analysis of data including historical groundwater levels and climate; hydro-chemical investigation and trend analysis of the historical hydro-chemical data; wavelet analysis of climate data; and the base flow index. The analyses indicate a clear warming trend and a decreasing trend in rainfall since the 1960s, in addition to increased human activities since the 1970s. The reduction of groundwater recharge in the past 30 years has led to a continuous depletion of groundwater levels, complex changes of the hydro-chemical environment, localized salinization, and a strong decline of the base flow to the river. It is expected that the results will contribute to a more comprehensive management plan for groundwater and the related eco-environment in the face of growing pressures from intensive human activities superimposed on climate change in this region.

  10. Real-time monitoring of smallholder farmer responses to intra-seasonal climate variability in central Kenya

    Science.gov (United States)

    Krell, N.; Evans, T. P.; Estes, L. D.; Caylor, K. K.

    2017-12-01

    While international metrics of food security and water availability are generated as spatial averages at the regional to national levels, climate variability impacts are differentially felt at the household level. This project investigated scales of variability of climate impacts on smallholder farmers using social and environmental data in central Kenya. Using sub-daily real-time environmental measurements to monitor smallholder agriculture, we investigated how changes in seasonal precipitation affected food security around Laikipia county from September 2015 to present. We also conducted SMS-based surveys of over 700 farmers to understand farmers' decision-making within the growing season. Our results highlight field-scale heterogeneity in biophysical and social factors governing crop yields using locally sensed real-time environmental data and weekly farmer-reported information about planting, harvesting, irrigation, and crop yields. Our preliminary results show relationships between changes in seasonal precipitation, NDVI, and soil moisture related to crop yields and decision-making at several scales. These datasets present a unique opportunity to collect highly spatially and temporally resolved information from data-poor regions at the household level.

  11. Generic antibiotics in Japan.

    Science.gov (United States)

    Fujimura, Shigeru; Watanabe, Akira

    2012-08-01

    Generic drugs have been used extensively in many developed countries, although their use in Japan has been limited. Generic drugs reduce drug expenses and thereby national medical expenditure. Because generic drugs provide advantages for both public administration and consumers, it is expected that they will be more widely used in the future. However, the diffusion rate of generic drugs in Japan is quite low compared with that of other developed countries. An investigation on generic drugs conducted by the Ministry of Health, Labour and Welfare in Japan revealed that 17.2 % of doctors and 37.2 % of patients had not used generic drugs. The major reasons for this low use rate included distrust of off-patent products and lower drug price margin compared with the brand name drug. The generic drugs available in the market include external drugs such as wet packs, antihypertensive agents, analgesics, anticancer drugs, and antibiotics. Among them, antibiotics are frequently used in cases of acute infectious diseases. When the treatment of these infections is delayed, the infection might be aggravated rapidly. The pharmacokinetics-pharmacodynamics (PK-PD) theory has been adopted in recent chemotherapy, and in many cases, the most appropriate dosage and administration of antibiotics are determined for individual patients considering renal function; high-dosage antibiotics are used preferably for a short duration. Therefore, a highly detailed antimicrobial agent is necessary. However, some of the generic antibiotics have less antibacterial potency or solubility than the brand name products. We showed that the potency of the generic products of vancomycin and teicoplanin is lower than that of the branded drugs by 14.6 % and 17.3 %, respectively. Furthermore, we confirmed that a generic meropenem drug for injection required about 82 s to solubilize in saline, whereas the brand product required only about 21 s. It was thought that the cause may be the difference in size of bulk

  12. Roux-en-Y gastric bypass reverses the effects of diet-induced obesity to inhibit the responsiveness of central vagal motoneurones.

    Science.gov (United States)

    Browning, Kirsteen N; Fortna, Samuel R; Hajnal, Andras

    2013-05-01

    Diet-induced obesity (DIO) has been shown to alter the biophysical properties and pharmacological responsiveness of vagal afferent neurones and fibres, although the effects of DIO on central vagal neurones or vagal efferent functions have never been investigated. The aims of this study were to investigate whether high-fat diet-induced DIO also affects the properties of vagal efferent motoneurones, and to investigate whether these effects were reversed following weight loss induced by Roux-en-Y gastric bypass (RYGB) surgery. Whole-cell patch-clamp recordings were made from rat dorsal motor nucleus of the vagus (DMV) neurones in thin brainstem slices. The DMV neurones from rats exposed to high-fat diet for 12-14 weeks were less excitable, with a decreased membrane input resistance and decreased ability to fire action potentials in response to direct current pulse injection. The DMV neurones were also less responsive to superfusion with the satiety neuropeptides cholecystokinin and glucagon-like peptide 1. Roux-en-Y gastric bypass reversed all of these DIO-induced effects. Diet-induced obesity also affected the morphological properties of DMV neurones, increasing their size and dendritic arborization; RYGB did not reverse these morphological alterations. Remarkably, independent of diet, RYGB also reversed age-related changes of membrane properties and occurrence of charybdotoxin-sensitive (BK) calcium-dependent potassium current. These results demonstrate that DIO also affects the properties of central autonomic neurones by decreasing the membrane excitability and pharmacological responsiveness of central vagal motoneurones and that these changes were reversed following RYGB. In contrast, DIO-induced changes in morphological properties of DMV neurones were not reversed following gastric bypass surgery, suggesting that they may be due to diet, rather than obesity. These findings represent the first direct evidence for the plausible effect of RYGB to improve vagal

  13. Low doses of a neonicotinoid insecticide modify pheromone response thresholds of central but not peripheral olfactory neurons in a pest insect.

    Science.gov (United States)

    Rabhi, Kaouther K; Deisig, Nina; Demondion, Elodie; Le Corre, Julie; Robert, Guillaume; Tricoire-Leignel, Hélène; Lucas, Philippe; Gadenne, Christophe; Anton, Sylvia

    2016-02-10

    Insect pest management relies mainly on neurotoxic insecticides, including neonicotinoids, leaving residues in the environment. There is now evidence that low doses of insecticides can have positive effects on pest insects by enhancing various life traits. Because pest insects often rely on sex pheromones for reproduction, and olfactory synaptic transmission is cholinergic, neonicotinoid residues could modify chemical communication. We recently showed that treatments with different sublethal doses of clothianidin could either enhance or decrease behavioural sex pheromone responses in the male moth, Agrotis ipsilon. We investigated now effects of the behaviourally active clothianidin doses on the sensitivity of the peripheral and central olfactory system. We show with extracellular recordings that both tested clothianidin doses do not influence pheromone responses in olfactory receptor neurons. Similarly, in vivo optical imaging does not reveal any changes in glomerular response intensities to the sex pheromone after clothianidin treatments. The sensitivity of intracellularly recorded antennal lobe output neurons, however, is upregulated by a lethal dose 20 times and downregulated by a dose 10 times lower than the lethal dose 0. This correlates with the changes of behavioural responses after clothianidin treatment and suggests the antennal lobe as neural substrate involved in clothianidin-induced behavioural changes. © 2016 The Author(s).

  14. 21 CFR 186.1555 - Japan wax.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Japan wax. 186.1555 Section 186.1555 Food and Drugs... Substances Affirmed as GRAS § 186.1555 Japan wax. (a) Japan wax (CAS Reg. No. 8001-39-6), also known as Japan... fruits of the oriental sumac, Rhus succedanea (Japan, Taiwan, and Indo-China), R. vernicifera (Japan...

  15. THE DIFFERENCE IN PEOPLE’S RESPONSE TOWARD NATURAL LANDSCAPE BETWEEN UNIVERSITY STUDENTS OF JAPAN AND INDONESIA (Perbedaan dalam Respon Manusia terhadap Lanskap Alami antara Pelajar Jepang dan Indonesia

    Directory of Open Access Journals (Sweden)

    Prita Indah Pratiwi

    2014-10-01

    Full Text Available ABSTRACT People in different culture distinguish in their response to the environment, especially in interpretation and understanding of the perceived landscape. In order to plan and manage the environment for the selection of landscape with the aim of special care, protection, and amenity, it is crucial that people effectively participate and measure the existing values which nature represents to local residents. The purpose of this study was to clarify the differences of landscape recognition of Japan and Indonesia and to find the landscape element which is highly valued. The study was conducted with the following six steps, namely, photos collection, photo grouping, preference evaluation, exoticism evaluation, analysis, and recommendation. Cluster analysis (Ward’s method, squared Euclidean distance was applied for the analysis of photo categories, and Mann-Whitney U Test was applied to examine the significant differences. In photo grouping, seven natural landscape photos of Japan and Indonesia were categorized in different groups. Forest photos were categorized as wetland by Japanese students. Two rivers, lake, and forest photos were categorized by Indonesian students, but Japanese students categorized it as forest and mountain in distant view. Japanese students also distinguished the wetland as wetland in distant view and wetland in close-up view. The results of preference evaluation show that significant differences were detected in 25 photos of 68 photos. The exoticism evaluation detected significant differences in 48 photos of 68 photos. Neither Japanese nor Indonesian students recognized forest and wetland. However, either the Japanese or Indonesian students preferred waterfall or coast than the others. Based on exoticism evaluation, river and wetland were not recognized, but coast and waterfall were recognized by both of countries. Both of countries shared commonality in landscape photographs evaluation of preference and exoticism

  16. Analysis Of Japans Economy Based On 2014 From Macroeconomics Prospects

    Directory of Open Access Journals (Sweden)

    Dr Mohammad Rafiqul Islam

    2015-02-01

    Full Text Available Abstract Japan is the worlds third largest economy. But currently economic situations of Japan are not stable. It is not increasing as expected. Since 2013 it was world second largest economy but Japan loosed its placed to China in 2014 due to slow growth of important economic indicators. By using the basic Keynesian model we will provide a detailed analysis of the short and long run impacts of the changes for Japans real GDP rate of unemployment and inflation rate. We demonstrated a detailed use of the 45-degree diagram or the AD-IA model and other economic analysis of the macroeconomic principles that underlie the model and concepts. Finally we will recommend the government with a change in fiscal policy what based on the analysis by considering what might be achieved with a fiscal policy response and the extent to which any impact on the stock of public debt might be a consideration

  17. Changes in central sodium and not osmolarity or lactate induce panic-like responses in a model of panic disorder.

    Science.gov (United States)

    Molosh, Andre I; Johnson, Philip L; Fitz, Stephanie D; Dimicco, Joseph A; Herman, James P; Shekhar, Anantha

    2010-05-01

    Panic disorder is a severe anxiety disorder characterized by recurrent panic attacks that can be consistently provoked with intravenous (i.v.) infusions of hypertonic (0.5 M) sodium lactate (NaLac), yet the mechanism/CNS site by which this stimulus triggers panic attacks is unclear. Chronic inhibition of GABAergic synthesis in the dorsomedial hypothalamus/perifornical region (DMH/PeF) of rats induces a vulnerability to panic-like responses after i.v. infusion of 0.5 M NaLac, providing an animal model of panic disorder. Using this panic model, we previously showed that inhibiting the anterior third ventricle region (A3Vr; containing the organum vasculosum lamina terminalis, the median preoptic nucleus, and anteroventral periventricular nucleus) attenuates cardiorespiratory and behavioral responses elicited by i.v. infusions of NaLac. In this study, we show that i.v. infusions of 0.5 M NaLac or sodium chloride, but not iso-osmolar D-mannitol, increased 'anxiety' (decreased social interaction) behaviors, heart rate, and blood pressure responses. Using whole-cell patch-clamp preparations, we also show that bath applications of NaLac (positive control), but not lactic acid (lactate stimulus) or D-mannitol (osmolar stimulus), increases the firing rates of neurons in the A3Vr, which are retrogradely labeled from the DMH/PeF and which are most likely glutamatergic based on a separate study using retrograde tracing from the DMH/PeF in combination with in situ hybridization for vesicular glutamate transporter 2. These data show that hypertonic sodium, but not hyper-osmolarity or changes in lactate, is the key stimulus that provokes panic attacks in panic disorder, and is consistent with human studies.

  18. Central Role of the PPARγ Gene Network in Coordinating Beef Cattle Intramuscular Adipogenesis in Response to Weaning Age and Nutrition

    OpenAIRE

    Moisá, Sonia J.; Shike, Daniel W.; Faulkner, Dan B.; Meteer, William T.; Keisler, Duane; Loor, Juan J.

    2014-01-01

    Adipogenic/lipogenic transcriptional networks regulating intramuscular fat deposition (IMF) in response to weaning age and dietary starch level were studied. The longissimus muscle (LM) of beef steers on an early weaning (141 days age) plus high-starch diet (EWS) or a normal weaning (NW, 222 days age) plus starch creep-feed diet (CFS) was biopsied at 0 (EW), 25, 50, 96 (NW), 167, and 222 (pre-slaughter) days. Expression patterns of 35 target genes were studied. From NW through slaughter, all ...

  19. Responses of plant water use to a severe summer drought for two subtropical tree species in the central southern China

    Directory of Open Access Journals (Sweden)

    Zidong Luo

    2016-12-01

    New hydrological insights: The results show that a decrease in water use during the drought for both two species is closely associated with an increase in vapor pressure deficit and a decrease in stem water potential. The two species appear to be anisohydric, but to a different degree in response to the drought. The hydrodynamic water potential gradient (Δψ maintains relatively constant with an average value of 0.59 MPa for C. camphora, and 1.59 MPa for O. fragrans. O. fragrans is less sensitive to drought than C. camphora, while C. camphora shows an effective survival mechanism via leaf shedding and dieback of shoots.

  20. Will Japan Rearm.

    Science.gov (United States)

    1977-06-10

    Faculty Accepte d th is _________ day of~~~U)~4 l977~c~y.11 -~~~~~~~~~~~~D i rector , Master of Militar y Art Science . The opinions and...j~ s’ri : ‘~~~~ ~ IC . _ __~~~~~~ i 1~~~~~n Unhi ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 150 _ _ _ _ _ _ _ _ _ _ L~ MASTER OF MILITARY ART ... SCIENCE THESIS APPROVAL PAGE Name of Candidate Joseph Bertrand Berger, Jr. Major, Air Defense Artillery T it le of Thes i s W i l l Japan Rearm

  1. Dosimetry studies in Japan

    International Nuclear Information System (INIS)

    Maruyama, T.; Kumamoto, Y.; Hashizume, T.

    1982-01-01

    In 1967 the National Institute of Radiological Sciences in Chiba estimated the radiation doses in air from the atomic bombing of Hiroshima and Nagasaki by using some building materials exposed to the nuclear explosions in both cities. These estimated doses were in good agreement with the doses estimated on the basis of the Ichiban project by the research group at Oak Ridge National Laboratory which were the basis for the Atomic Bomb Casualty Commission's tentative 1965 radiation dose (T65D). Recently the radiation doses in Hiroshima and Nagasaki have been reevaluated by Lawrence Livermore National Laboratory and Oak Ridge National Laboratory. In Japan a new research group was started last August, with the intention of making new estimates of doses from the atomic bombs in cooperation with US research groups

  2. Radiation processing in Japan

    International Nuclear Information System (INIS)

    Makuuchi, Keizo

    2001-01-01

    Economic scale of radiation application in the field of industry, agriculture and medicine in Japan in 1997 was investigated to compare its economic impacts with that of nuclear energy industry. Total production value of radiation application accounted for 54% of nuclear industry including nuclear energy industry and radiation applications in three fields above. Industrial radiation applications were further divided into five groups, namely nondestructive test, RI instruments, radiation facilities, radiation processing and ion beam processing. More than 70% of the total production value was brought about by ion beam processing for use with IC and semiconductors. Future economic prospect of radiation processing of polymers, for example cross-linking, EB curing, graft polymerization and degradation, is reviewed. Particular attention was paid to radiation vulcanization of natural rubber latex and also to degradation of natural polymers. (S. Ohno)

  3. Radiation processing in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Makuuchi, Keizo [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    2001-03-01

    Economic scale of radiation application in the field of industry, agriculture and medicine in Japan in 1997 was investigated to compare its economic impacts with that of nuclear energy industry. Total production value of radiation application accounted for 54% of nuclear industry including nuclear energy industry and radiation applications in three fields above. Industrial radiation applications were further divided into five groups, namely nondestructive test, RI instruments, radiation facilities, radiation processing and ion beam processing. More than 70% of the total production value was brought about by ion beam processing for use with IC and semiconductors. Future economic prospect of radiation processing of polymers, for example cross-linking, EB curing, graft polymerization and degradation, is reviewed. Particular attention was paid to radiation vulcanization of natural rubber latex and also to degradation of natural polymers. (S. Ohno)

  4. Ultrasound assisted extraction of bioactive compounds from Nephelium lappaceum L. fruit peel using central composite face centered response surface design

    Directory of Open Access Journals (Sweden)

    J. Prakash Maran

    2017-02-01

    Full Text Available In this study, four factors at three level central composite face centered design was employed to study and optimize the process variables on extraction of bioactive compounds (total anthocyanin, phenolic and flavonoid content from Nephelium lappaceum L. fruit peel. The effect of process variables such as extraction temperature (30–50 °C, power of ultrasound (20–40 W, extraction time (10–30 min and solid–liquid ratio (1:10–1:20 g/ml is studied. Multiple regression analysis was done on the experimental data to develop second-order polynomial models with high coefficient of determination value (R2 > 0.99. The optimal conditions based on both individual and combinations of all process variables (extraction temperature of 50 °C, ultrasound power of 20 W, extraction time of 20 min and solid–liquid ratio of 1:18.6 g/ml were determined by Derringer’s desired function methodology. Under these conditions, total anthocyanin (10.26 ± 0.39 (mg/100 g, phenolics (552.64 ± 1.57 (mg GAE/100 g and flavonoid (104 ± 1.13 (mg RE/100 g content values were determined and it is closely related with the predicted values (10.17 mg/100 g of total anthocyanin, 546.98 mg GAE/100 g of total phenolics and 100.93 mg RE/100 g of total flavonoid content and indicted the suitability of the developed models.

  5. Central canal ependymal cells proliferate extensively in response to traumatic spinal cord injury but not demyelinating lesions.

    Directory of Open Access Journals (Sweden)

    Steve Lacroix

    Full Text Available The adult mammalian spinal cord has limited regenerative capacity in settings such as spinal cord injury (SCI and multiple sclerosis (MS. Recent studies have revealed that ependymal cells lining the central canal possess latent neural stem cell potential, undergoing proliferation and multi-lineage differentiation following experimental SCI. To determine whether reactive ependymal cells are a realistic endogenous cell population to target in order to promote spinal cord repair, we assessed the spatiotemporal dynamics of ependymal cell proliferation for up to 35 days in three models of spinal pathologies: contusion SCI using the Infinite Horizon impactor, focal demyelination by intraspinal injection of lysophosphatidylcholine (LPC, and autoimmune-mediated multi-focal demyelination using the active experimental autoimmune encephalomyelitis (EAE model of MS. Contusion SCI at the T9-10 thoracic level stimulated a robust, long-lasting and long-distance wave of ependymal proliferation that peaked at 3 days in the lesion segment, 14 days in the rostral segment, and was still detectable at the cervical level, where it peaked at 21 days. This proliferative wave was suppressed distal to the contusion. Unlike SCI, neither chemical- nor autoimmune-mediated demyelination triggered ependymal cell proliferation at any time point, despite the occurrence of demyelination (LPC and EAE, remyelination (LPC and significant locomotor defects (EAE. Thus, traumatic SCI induces widespread and enduring activation of reactive ependymal cells, identifying them as a robust cell population to target for therapeutic manipulation after contusion; conversely, neither demyelination, remyelination nor autoimmunity appears sufficient to trigger proliferation of quiescent ependymal cells in models of MS-like demyelinating diseases.

  6. Oxytocin differently regulates pressor responses to stress in WKY and SHR rats: the role of central oxytocin and V1a receptors.

    Science.gov (United States)

    Wsol, A; Szczepanska-Sadowska, E; Kowalewski, S; Puchalska, L; Cudnoch-Jedrzejewska, A

    2014-01-01

    The role of central oxytocin in the regulation of cardiovascular parameters under resting conditions and during acute stress was investigated in male normotensive Wistar-Kyoto (WKY; n = 40) and spontaneously hypertensive rats (SHR; n = 28). In Experiment 1, mean arterial blood pressure (MABP) and heart rate (HR) were recorded in WKY and SHR rats at rest and after an air-jet stressor during intracerebroventricular (ICV) infusions of vehicle, oxytocin or oxytocin receptor (OTR) antagonist. In Experiment 2, the effects of vehicle, oxytocin and OTR antagonist were determined in WKY rats after prior administration of a V1a vasopressin receptor (V1aR) antagonist. Resting MABP and HR were not affected by any of the ICV infusions either in WKY or in SHR rats. In control experiments (vehicle), the pressor response to stress was significantly higher in SHR. Oxytocin enhanced the pressor response to stress in the WKY rats but reduced it in SHR. During V1aR blockade, oxytocin infusion entirely abolished the pressor response to stress in WKY rats. Combined blockade of V1aR and OTR elicited a significantly greater MABP response to stress than infusion of V1a antagonist and vehicle. This study reveals significant differences in the regulation of blood pressure in WKY and SHR rats during alarming stress. Specifically, the augmentation of the pressor response to stress by exogenous oxytocin in WKY rats is caused by its interaction with V1aR, and endogenous oxytocin regulates the magnitude of the pressor response to stress in WKY rats by simultaneous interaction with OTR and V1aR.

  7. SCWR Concepts in Japan

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2014-08-15

    Two SCWR concepts are being developed in Japan, one corresponding to the thermal spectrum reactor and the other to the fast spectrum reactor. Yamada et al. described the thermal-spectrum reactor concept referred to as the Japan SCWR (or JSCWR). This concept was developed under the financial support of the Ministry of Economy, Trade and Industry (METI). The basic philosophy of the JSCWR development is to utilize proven light water reactor and supercritical fossil-fired power plant technologies as much as possible to minimize the R&D cost, time and risks. Therefore, the JSCWR is designed as a thermal neutron spectrum reactor using light water as moderator and reactor coolant. The JSCWR plant consists of a pressure-vessel type, once-through reactor and a direct Rankine cycle system. Reactor coolant fed through inlet nozzles is heated up in the core and flows through outlet nozzles with no recirculation in the vessel. Other options to the JSCWR core design are being investigated at the University of Tokyo. The electric output of the JSCWR is assumed to range from 600 MWe to 1700 MWe class to fulfill user’s requirements as much as possible. In this section, the reference value is selected to 1725 MWe, which corresponds to a reactor thermal output of 4039 MWth. Nakatsuka et al. described the core design for the fast-spectrum reactor, which is based on a similar plant system compared to that of the thermal-spectrum reactor. The fast-spectrum reactor, however, would produce higher power rating than the thermal-spectrum one of the same reactor pressure-vessel size. Since the fast-spectrum reactor does not require the moderator, its unit capital cost would be lower than the thermal-spectrum reactor.

  8. White-throated Sparrow Response to Forest Harvesting in North-Central Alberta: Results Not So Clear-Cut?

    Directory of Open Access Journals (Sweden)

    Kevin C. Hannah

    2008-06-01

    Full Text Available The use of density to measure a species' responses to habitat change remains prevalent despite warnings that relying on such parameters can be misleading. We evaluated whether density was a useful surrogate of habitat quality for the White-throated Sparrow (Zonotrichia albicollis, an apparent habitat generalist, in a recently logged landscape near Calling Lake, Alberta, Canada. We detected significant differences in the territory density of birds among three distinct habitat types: interior forest, forest edges, and recent (4- to 6-yr-old clear-cuts. However, the observed patterns in territory density were not consistent with several indices of habitat quality. We found a consistent and marked gradient for indices such as nesting success (based on a reproductive index, pairing success, and the proportion of territories that successfully fledged young between interior forest sites and clear-cuts. Edge habitats, in which high relative density offset lower reproductive success, represented moderate-quality habitat for this species. Our results suggest that the continued use of density alone, without some measure of habitat quality, is insufficient if not misleading when evaluating response to habitat change. Our results have important implications for understanding the population dynamics of this species, which is often overlooked in population-level studies yet continues to experience long-term population declines over large portions of its breeding range.

  9. Central Role of the PPARγ Gene Network in Coordinating Beef Cattle Intramuscular Adipogenesis in Response to Weaning Age and Nutrition.

    Science.gov (United States)

    Moisá, Sonia J; Shike, Daniel W; Faulkner, Dan B; Meteer, William T; Keisler, Duane; Loor, Juan J

    2014-01-01

    Adipogenic/lipogenic transcriptional networks regulating intramuscular fat deposition (IMF) in response to weaning age and dietary starch level were studied. The longissimus muscle (LM) of beef steers on an early weaning (141 days age) plus high-starch diet (EWS) or a normal weaning (NW, 222 days age) plus starch creep-feed diet (CFS) was biopsied at 0 (EW), 25, 50, 96 (NW), 167, and 222 (pre-slaughter) days. Expression patterns of 35 target genes were studied. From NW through slaughter, all steers received the same high-starch diet. In EWS steers the expression of PPARG, other adipogenic (CEBPA, ZFP423) and lipogenic (THRSP, SREBF1, INSIG1) activators, and several enzymes (FASN, SCD, ELOVL6, PCK1, DGAT2) that participate in the process of IMF increased gradually to a peak between 96 and 167 days on treatment. Steers in NW did not achieve similar expression levels even by 222 days on treatment, suggesting a blunted response even when fed a high-starch diet after weaning. High-starch feeding at an early age (EWS) triggers precocious and sustained adipogenesis, resulting in greater marbling.

  10. Interleukin-17 receptor A (IL-17RA) as a central regulator of the protective immune response against Giardia.

    Science.gov (United States)

    Paerewijck, Oonagh; Maertens, Brecht; Dreesen, Leentje; Van Meulder, Frederik; Peelaers, Iris; Ratman, Dariusz; Li, Robert W; Lubberts, Erik; De Bosscher, Karolien; Geldhof, Peter

    2017-08-17

    The protozoan parasite Giardia is a highly prevalent intestinal pathogen with a wide host range. Data obtained in mice, cattle and humans revealed the importance of IL-17A in the development of a protective immune response against Giardia. The aim of this study was to further unravel the protective effector mechanisms triggered by IL-17A following G. muris infection in mice, by an RNA-sequencing approach. C57BL/6 WT and C57BL/6 IL-17RA KO mice were orally infected with G. muris cysts. Three weeks post infection, intestinal tissue samples were collected for RNA-sequencing, with samples from uninfected C57BL/6 WT and C57BL/6 IL-17RA KO animals serving as negative controls. Differential expression analysis showed that G. muris infection evoked the transcriptional upregulation of a wide array of genes, mainly in animals with competent IL-17RA signaling. IL-17RA signaling induced the production of various antimicrobial peptides, such as angiogenin 4 and α- and β-defensins and regulated complement activation through mannose-binding lectin 2. The expression of the receptor that regulates the secretion of IgA into the intestinal lumen, the polymeric immunoglobulin receptor, was also dependent on IL-17RA signaling. Interestingly, the transcriptome data showed for the first time the involvement of the circadian clock in the host response following Giardia infection.

  11. Developmental lead exposure induces opposite effects on ethanol intake and locomotion in response to central vs. systemic cyanamide administration.

    Science.gov (United States)

    Mattalloni, Mara Soledad; Deza-Ponzio, Romina; Albrecht, Paula Alejandra; Cancela, Liliana Marina; Virgolini, Miriam Beatriz

    2017-02-01

    Lead (Pb) is a developmental neurotoxicant that elicits differential responses to drugs of abuse. Particularly, ethanol consumption has been demonstrated to be increased as a consequence of environmental Pb exposure, with catalase (CAT) and brain acetaldehyde (ACD, the first metabolite of ethanol) playing a role. The present study sought to interfere with ethanol metabolism by inhibiting ALDH2 (mitochondrial aldehyde dehydrogenase) activity in both liver and brain from control and Pb-exposed rats as a strategy to accumulate ACD, a substance that plays a major role in the drug's reinforcing and/or aversive effects. To evaluate the impact on a 2-h chronic voluntary ethanol intake test, developmentally Pb-exposed and control rats were administered with cyanamide (CY, an ALDH inhibitor) either systemically or intracerebroventricularly (i.c.v.) on the last 4 sessions of the experiment. Furthermore, on the last session and after locomotor activity was assessed, all animals were sacrificed to obtain brain and liver samples for ALDH2 and CAT activity determination. Systemic CY administration reduced the elevated ethanol intake already reported in the Pb-exposed animals (but not in the controls) accompanied by liver (but not brain) ALDH2 inactivation. On the other hand, a 0.3 mg i.c.v. CY administration enhanced both ethanol intake and locomotor activity accompanied by brain ALDH2 inactivation in control animals, while an increase in ethanol consumption was also observed in the Pb-exposed group, although in the absence of brain ALDH2 blockade. No changes were observed in CAT activity as a consequence of CY administration. These results support the participation of liver and brain ACD in ethanol intake and locomotor activity, responses that are modulated by developmental Pb exposure. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. China-Japan-Korea (CJK)'s FTA Strategy towards ASEAN Countries: A Game Theoretical Approach

    OpenAIRE

    Fithra Faisal Hastiadi

    2012-01-01

    This paper analyzes the FTA strategies of China, Japan and Korea (CJK) toward ASEAN countries using a three-player game. It explores the implications of China, Japan, and/or Korea participating in an FTA with ASEAN and the corresponding rewards in a payoff matrix. The Nash equilibrium occurs when China, Korea and Japan all choose to participate in an FTA with ASEAN. Dominant strategies and response functions for each country are analyzed using Error Correction Mechanism (ECM) and Vector Auto ...

  13. The Post-Eocene Evolution of the Doruneh Fault Region (Central Iran): The Intraplate Response to the Reorganization of the Arabia-Eurasia Collision Zone

    Science.gov (United States)

    Tadayon, Meisam; Rossetti, Federico; Zattin, Massimiliano; Nozaem, Reza; Calzolari, Gabriele; Madanipour, Saeed; Salvini, Francesco

    2017-12-01

    The Cenozoic deformation history of Central Iran has been dominantly accommodated by the activation of major intracontinental strike-slip fault zones, developed in the hinterland domain of the Arabia-Eurasia convergent margin. Few quantitative temporal and kinematic constraints are available from these strike-slip deformation zones, hampering a full assessment of the style and timing of intraplate deformation in Iran and the understanding of the possible linkage to the tectonic reorganization of the Zagros collisional zone. This study focuses on the region to the north of the active trace of the sinistral Doruneh Fault. By combing structural and low-temperature apatite fission track (AFT) and (U-Th)/He (AHe) thermochronology investigations, we provide new kinematic and temporal constraints to the deformation history of Central Iran. Our results document a post-Eocene polyphase tectonic evolution dominated by dextral strike-slip tectonics, whose activity is constrained since the early Miocene in response to an early, NW-SE oriented paleo-σ1 direction. A major phase of enhanced cooling/exhumation is constrained at the Miocene/Pliocene boundary, caused by a switch of the maximum paleo-σ1 direction to N-S. When integrated into the regional scenario, these data are framed into a new tectonic reconstruction for the Miocene-Quaternary time lapse, where strike-slip deformation in the intracontinental domain of Central Iran is interpreted as guided by the reorganization of the Zagros collisional zone in the transition from an immature to a mature stage of continental collision.

  14. Romanticising Shinsengumi in Contemporary Japan

    Directory of Open Access Journals (Sweden)

    Rosa Lee

    2011-01-01

    Full Text Available Shinsengumi, a group of young men recruited by the Bakufu to protect Kyoto from radical Imperial House loyalists in the tumultuous Bakumatsu period, is romanticised and idolised in Japan despite its limited place in history. This article attempts to comprehend this phenomenon by locating the closest crystallisation of popularly imagined Shinsengumi in Moeyo ken, a popular historical fiction by Shiba Ryōtarō. Antonio Gramsci explains readers are attracted to popular literature because it reflects their ‘philosophies of the age’, which may be discovered by examining popular heroes with their subsequent replications. This article will identify why Shinsengumi is appealing by comparing Shiba’s hero in Moeyo ken with its twenty-first century reincarnation in Gintama, a popular manga series, and by discerning reader response to Moeyo ken from customer reviews on Amazon.co.jp. It will be demonstrated from these studies that a likely reason for the Japanese public’s romanticisation of Shinsengumi in recent years could be their attraction to autonomous, self-determining heroes who also appreciate the value of community.

  15. Elucidating the Role of Injury-Induced Electric Fields (EFs in Regulating the Astrocytic Response to Injury in the Mammalian Central Nervous System.

    Directory of Open Access Journals (Sweden)

    Matthew L Baer

    Full Text Available Injury to the vertebrate central nervous system (CNS induces astrocytes to change their morphology, to increase their rate of proliferation, and to display directional migration to the injury site, all to facilitate repair. These astrocytic responses to injury occur in a clear temporal sequence and, by their intensity and duration, can have both beneficial and detrimental effects on the repair of damaged CNS tissue. Studies on highly regenerative tissues in non-mammalian vertebrates have demonstrated that the intensity of direct-current extracellular electric fields (EFs at the injury site, which are 50-100 fold greater than in uninjured tissue, represent a potent signal to drive tissue repair. In contrast, a 10-fold EF increase has been measured in many injured mammalian tissues where limited regeneration occurs. As the astrocytic response to CNS injury is crucial to the reparative outcome, we exposed purified rat cortical astrocytes to EF intensities associated with intact and injured mammalian tissues, as well as to those EF intensities measured in regenerating non-mammalian vertebrate tissues, to determine whether EFs may contribute to the astrocytic injury response. Astrocytes exposed to EF intensities associated with uninjured tissue showed little change in their cellular behavior. However, astrocytes exposed to EF intensities associated with injured tissue showed a dramatic increase in migration and proliferation. At EF intensities associated with regenerating non-mammalian vertebrate tissues, these cellular responses were even more robust and included morphological changes consistent with a regenerative phenotype. These findings suggest that endogenous EFs may be a crucial signal for regulating the astrocytic response to injury and that their manipulation may be a novel target for facilitating CNS repair.

  16. Elucidating the Role of Injury-Induced Electric Fields (EFs) in Regulating the Astrocytic Response to Injury in the Mammalian Central Nervous System.

    Science.gov (United States)

    Baer, Matthew L; Henderson, Scott C; Colello, Raymond J

    2015-01-01

    Injury to the vertebrate central nervous system (CNS) induces astrocytes to change their morphology, to increase their rate of proliferation, and to display directional migration to the injury site, all to facilitate repair. These astrocytic responses to injury occur in a clear temporal sequence and, by their intensity and duration, can have both beneficial and detrimental effects on the repair of damaged CNS tissue. Studies on highly regenerative tissues in non-mammalian vertebrates have demonstrated that the intensity of direct-current extracellular electric fields (EFs) at the injury site, which are 50-100 fold greater than in uninjured tissue, represent a potent signal to drive tissue repair. In contrast, a 10-fold EF increase has been measured in many injured mammalian tissues where limited regeneration occurs. As the astrocytic response to CNS injury is crucial to the reparative outcome, we exposed purified rat cortical astrocytes to EF intensities associated with intact and injured mammalian tissues, as well as to those EF intensities measured in regenerating non-mammalian vertebrate tissues, to determine whether EFs may contribute to the astrocytic injury response. Astrocytes exposed to EF intensities associated with uninjured tissue showed little change in their cellular behavior. However, astrocytes exposed to EF intensities associated with injured tissue showed a dramatic increase in migration and proliferation. At EF intensities associated with regenerating non-mammalian vertebrate tissues, these cellular responses were even more robust and included morphological changes consistent with a regenerative phenotype. These findings suggest that endogenous EFs may be a crucial signal for regulating the astrocytic response to injury and that their manipulation may be a novel target for facilitating CNS repair.

  17. Cortisol stress response is positively correlated with central obesity in obese women with binge eating disorder (BED) before and after cognitive-behavioral treatment.

    Science.gov (United States)

    Gluck, Marci E; Geliebter, Allan; Lorence, Margarita

    2004-12-01

    Stress is the most commonly reported trigger of binge eating, and high cortisol levels are positively related to both central body fat and food intake after laboratory stress. We therefore examined waist circumference (WHR) and cortisol stress responsivity after a cold pressor stress test (CPT) in 22 obese (BMI > 27) women (11 BED, 11 non-BED). BMI and WHR did not differ between groups. The BED group had higher morning basal cortisol than the non-BED group (P = .03) and greater AUC cortisol after CPT, after controlling for AUC insulin (P = .04). In the BED group, WHR was related to AUC cortisol (P = .002) and peak cortisol stress responsivity (P = .003). Twenty (10 non-BED, 10 BED) were randomized to a 6-week treatment program (CBT + Diet) or Wait-List (WL) control group. There were no BED group or treatment-group differences in WHR, morning basal cortisol, or AUC cortisol after CPT. The relationship between WHR and both AUC cortisol (P = .002) and peak cortisol stress responsivity after CPT (P = .008) remained significant in the BED group. In BED, there is a hyperactive HPA axis related to abdominal obesity that persists even after treatment, suggesting that cortisol might be a primary factor in the disorder.

  18. Is banking supervision central to central banking?

    OpenAIRE

    Joe Peek; Eric S. Rosengren; Geoffrey M. B. Tootell

    1997-01-01

    Whether central banks should play an active role in bank supervision and regulation is being debated both in the United States and abroad. While the Bank of England has recently been stripped of its supervisory responsibilities and several proposals in the United States have advocated removing bank supervision from the Federal Reserve System, other countries are considering enhancing central bank involvement in this area. Many of the arguments for and against these proposals hinge on the effe...

  19. MEN`S PHYSICAL, PSYCHOLOGICAL AND SOCIAL RESPONSE TO VASECTOMY ACCEPTOR OF FAMILY PLANNING PROGRAM IN SUKOHARJO CENTRAL JAVA

    Directory of Open Access Journals (Sweden)

    Winarsih Nur Ambarwati

    2017-04-01

    Full Text Available Introduction: Indonesia is on the fourth position in the world as the most populated nation in 2009. Great number of people with lack of skill would give potential burden in the nation development. Generally, the outcome of Indonesian Family Planing Program(FPP acceptor to Indonesian women is sufficient which is ranging to 59 percent of the total 60,3 percent of participants but if compared to men's participation in is still insignificant. Husband's participation as participant is still low 1.3% consisted of 0.9 percent condom user, 0.4 percent vasectomy user. To describe experiences of Indonesian men following vasectomy in relation to their physical, psychological and social responses to vasectomy. Method: The research design of this research uses descriptive qualitative study. The sample selection was done using theoretical sampling technique. The data collection instrument of grounded theory research is the researcher herself, while other instruments are namely field report, audiotape, videotape, and notes. The data analysis is utilized Colaizzi`s method. Result: Numbers of participants were 7 persons. Physical change after the vasectomy surgery is on general physical change (there is no change felt, the body's stamina raises, healthier, less energy, or weary and physical change on reproduction organ is none. Sexual ability has no change, it increases, it also decreases. The sexual satisfaction is the same, more satisfi ed, or less satisfied. The characteristic change of spermatid is the same, there is change (lesser quantity, more dissolved, and ignore it. All participants said that they feel more comfortable in doing sex after vasectomy surgery. Most participants feel confidence of their sexual ability. The participants' perspective had no difference and feel difference, or there is a change. Most participants stated that vasectomy is the right decision, but few felt disappointed. The social environment response toward men as the

  20. Response of Functional Structure of Soil Microbial Community to Multi-level Nitrogen Additions on the Central Tibetan Plateau

    Science.gov (United States)

    Zhang, G.; Yuan, Y.

    2015-12-01

    The use of fossil fuels and fertilizers has increased the amount of biologically reactive nitrogen in the atmosphere over the past century. Tibet is the one of the most threatened regions by nitrogen deposition, thus understanding how its microbial communities function maybe of high importance to predicting microbial responses to nitrogen deposition. Here we describe a short-time nitrogen addition conducted in an alpine steppe ecosystem to investigate the response of functional structure of soil microbial community to multi-level nitrogen addition. Using a GeoChip 4.0, we showed that functional diversities and richness of functional genes were unchanged at low level of nitrogen fertilizer inputs (=40 kg N ha-1 yr-1). Detrended correspondence analysis indicated that the functional structure of microbial communities was markedly different across the nitrogen gradients. Most C degradation genes whose abundances significantly increased under elevated N fertilizer were those involved in the degradation of relatively labile C (starch, hemicellulose, cellulose), whereas the abundance of certain genes involved in the degradation of recalcitrant C (i.e. lignin) was largely decreased (such as manganese peroxidase, mnp). The results suggest that the elevated N fertilization rates might significantly accelerate the labile C degradation, but might not spur recalcitrant C degradation. The combined effect of gdh and ureC genes involved in N cycling appeared to shift the balance between ammonia and organic N toward organic N ammonification and hence increased the N mineralization potential. Moreover, Urease directly involved in urea mineralization significantly increased. Lastly, Canonical correspondence analysis showed that soil (TOC+NH4++NO3-+NO2-+pH) and plant (Aboveground plant productivity + Shannon Diversity) variables could explain 38.9% of the variation of soil microbial community composition. On the basis of above observations, we predict that increasing of nitrogen

  1. Trauma and posttraumatic stress disorder in Japan: Results from the World Mental Health Japan Survey

    Science.gov (United States)

    Kawakami, Norito; Tsuchiya, Masao; Umeda, Maki; Koenen, Karestan C.; Kessler, Ronald C.

    2014-01-01

    The purpose of the study was to report the prevalence of trauma exposure and PTSD, conditional risk of PTSD associated with each trauma exposure in the community population in Japan. An interview survey was conducted of a random sample of adult residents in 11 communities of Japan. Among 4134 respondents (response rate, 55%), data from those who completed the part 2 interview (n = 1682) were analyzed with a weight for this subsample. Lifetime experiences of 27 trauma events and PTSD were assessed using the WHO-Composite International Diagnostic Interview version 3.0. Sixty percent of the part 2 sample reported exposure to at least one lifetime traumatic event. Lifetime and 12-month PTSD prevalences were 1.3% and 0.7%, respectively. Percentage of all months lived with PTSD in the population was predominantly accounted for by physical/sexual assaults and having a child with serious illness, and unexpected death of loved one. Ten percent of respondents reported “private events”, for which respondents did not have to describe the content, which accounted for 19% of months with PTSD. The lower prevalence of PTSD in Japan seems attributable to lower conditional risks of PTSD following these events, as well as different distributions of the events. The greater impact of events that occurred to loved ones rather than to oneself and “private events” on PTSD in Japan warrants further research of cross-cultural assessment of trauma exposure and cultural heterogeneity in the trauma-PTSD relationship. PMID:24572682

  2. Response of vegetation NDVI to climatic extremes in the arid region of Central Asia: a case study in Xinjiang, China

    Science.gov (United States)

    Yao, Junqiang; Chen, Yaning; Zhao, Yong; Mao, Weiyi; Xu, Xinbing; Liu, Yang; Yang, Qing

    2018-02-01

    Observed data showed the climatic transition from warm-dry to warm-wet in Xinjiang during the past 30 years and will probably affect vegetation dynamics. Here, we analyze the interannual change of vegetation index based on the satellite-derived normalized difference vegetation index (NDVI) with temperature and precipitation extreme over the Xinjiang, using the 8-km NDVI third-generation (NDVI3g) from the Global Inventory Modelling and Mapping Studies (GIMMS) from 1982 to 2010. Few previous studies analyzed the link between climate extremes and vegetation response. From the satellite-based results, annual NDVI significantly increased in the first two decades (1981-1998) and then decreased after 1998. We show that the NDVI decrease over the past decade may conjointly be triggered by the increases of temperature and precipitation extremes. The correlation analyses demonstrated that the trends of NDVI was close to the trend of extreme precipitation; that is, consecutive dry days (CDD) and torrential rainfall days (R24) positively correlated with NDVI during 1998-2010. For the temperature extreme, while the decreases of NDVI correlate positively with warmer mean minimum temperature ( Tnav), it correlates negatively with the number of warmest night days ( Rwn). The results suggest that the climatic extremes have possible negative effects on the ecosystem.

  3. The Cogema group in Japan

    International Nuclear Information System (INIS)

    1998-12-01

    The partnership between the Cogema group and Japan in the domain of fuel cycle started about 20 years ago and the 10 Japanese nuclear operators are all clients of the Cogema group. The 1997 turnover realized with Japan reached 3.6 billions of francs (11% of the total turnover of the group). This short paper presents briefly the nuclear program of Japan (nuclear park, spent fuels reprocessing-recycling strategy) and the contracts between Cogema and the Japanese nuclear operators (natural uranium, uranium conversion and enrichment, spent fuel reprocessing, plutonium recycle and MOX fuel production markets). (J.S.)

  4. Dynamic axes of informed consent in Japan.

    Science.gov (United States)

    Specker Sullivan, Laura

    2017-02-01

    Scholarship in cross-cultural bioethics routinely frames Japanese informed consent in contrast to informed consent in North America. This contrastive analysis foregrounds cancer diagnosis disclosure and physician paternalism as unique aspects of Japanese informed consent that deviate from American practices. Drawing on in-depth interviews with 15 Japanese medical professionals obtained during fieldwork in Japan from 2013 to 15, this article complicates the informed consent discourse beyond East-West comparisons premised on Anglo-American ethical frameworks. It expands professional perspectives to include nurses, medical social workers, clinical psychologists, and ethicists and it addresses informed consent for a broad range of conditions in addition to cancer. The results suggest that division of affective labor is an under-theorized dimension of informed consent that is perceived as at odds with principled demands for universal informed consent. These practical tensions are conceptualized as cultural differences, with Japan identified in terms of omakase as practical and supportive and the United States identified in terms of jiko kettei as principled and self-determining. These results have implications for the methodology of cross-cultural bioethics as well as for theories and practices of informed consent in both Japan and the United States. I conclude that responsible cross-cultural work in bioethics must begin from the ground up, incorporating all relevant stakeholder perspectives, attitudes, and experiences. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Vegetation response to the "African Humid Period" termination in Central Cameroon (7° N – new pollen insight from Lake Mbalang

    Directory of Open Access Journals (Sweden)

    M. Servant

    2010-05-01

    Full Text Available A new pollen sequence from the Lake Mbalang (7°19´ N, 13°44´ E, 1110 m a.s.l. located on the eastern Adamawa plateau, in Central Cameroon, is presented in this paper to analyze the Holocene African Humid Period (AHP termination and related vegetation changes at 7° N in tropical Africa, completing an important transect for exploring shifts in the northern margin of the African Monsoon. This sequence, spanning the last 7000 cal yr BP, shows that the vegetation response to this transitional climatic period was marked by significant successional changes within the broad context of long-term aridification. Semi-deciduous/sub-montane forest retreat in this area is initially registered as early as ca. 6100 cal yr BP and modern savannah was definitely established at ca. 3000 cal yr BP and stabilized at ca. 2400 cal yr BP; but a slight forest regeneration episode is observed between ca. 5200 and ca. 4200 cal yr BP. In this area with modern high rainfall, increasing in the length of the dry season during the AHP termination linked to a contraction of the northern margin of the Intertropical Convergence Zone (ITCZ from ca. 6100 cal yr BP onward, probably associated with decreasing in cloud cover and/or fog frequency, has primarily controlled vegetation dynamics and above all the disappearance of the forested environment on the Adamawa plateau. Compared to previous studies undertaken in northern tropical and Central Africa, this work clearly shows that the response of vegetation to transitional periods between climatic extremes such as the AHP termination might be different in timing, mode and amplitude according to the regional climate of the study sites, but also according to the stability of vegetation before and during these climatic transitions.

  6. The influence of μ-opioid and noradrenaline reuptake inhibition in the modulation of pain responsive neurones in the central amygdala by tapentadol in rats with neuropathy

    Science.gov (United States)

    Gonçalves, Leonor; Friend, Lauren V.; Dickenson, Anthony H.

    2015-01-01

    Treatments for neuropathic pain are either not fully effective or have problematic side effects. Combinations of drugs are often used. Tapentadol is a newer molecule that produces analgesia in various pain models through two inhibitory mechanisms, namely central μ-opioid receptor (MOR) agonism and noradrenaline reuptake inhibition. These two components interact synergistically, resulting in levels of analgesia similar to opioid analgesics such as oxycodone and morphine, but with more tolerable side effects. The right central nucleus of the amygdala (CeA) is critical for the lateral spinal ascending pain pathway, regulates descending pain pathways and is key in the emotional-affective components of pain. Few studies have investigated the pharmacology of limbic brain areas in pain models. Here we determined the actions of systemic tapentadol on right CeA neurones of animals with neuropathy and which component of tapentadol contributes to its effect. Neuronal responses to multimodal peripheral stimulation of animals with spinal nerve ligation or sham surgery were recorded before and after two doses of tapentadol. After the higher dose of tapentadol either naloxone or yohimbine were administered. Systemic tapentadol resulted in dose-dependent decrease in right CeA neuronal activity only in neuropathy. Both naloxone and yohimbine reversed this effect to an extent that was modality selective. The interactions of the components of tapentadol are not limited to the synergy between the MOR and α2-adrenoceptors seen at spinal levels, but are seen at this supraspinal site where suppression of responses may relate to the ability of the drug to alter affective components of pain. PMID:25576174

  7. Seed size influence on germination responses to light and temperature of seven pioneer tree species from the Central Amazon

    Directory of Open Access Journals (Sweden)

    Fabiana F. Aud

    2012-09-01

    Full Text Available In Amazon secondary forests are dominated by pioneer species that typically produce large amounts of small and dormant seeds that are able to form a persistent soil seed bank. Seed dormancy in this group of species is overcome by environmental conditions found in open areas, such as high irradiation or alternating temperatures. Nevertheless, a variety of germination responses to environmental factors is known among pioneers; some of them may germinate in diffuse light or in darkness condition at constant temperature. Seed mass can be considered as one of the factors that promotes this variety. Regarding species with very small seeds, it seems that the trigger for germination is light and for larger seeds temperature alternation may be a more important stimulus. In this study we established a relationship between seed mass and germination response to light and alternating temperature for a group of seven woody pioneer species from the Amazon forest. We found that an increase in seed mass was followed by a decrease in the need for light and an increase in the tolerance to alternating temperatures. Understanding germination strategies may contribute with the knowledge of species coexistence in high diverse environments and also may assist those involved in forest management and restoration.Na Amazônia as florestas secundárias são dominadas por espécies pioneiras que, normalmente, produzem grandes quantidades de sementes pequenas, dormentes e capazes de formar bancos de sementes no solo. A dormência neste grupo de espécies é superada pelas condições ambientais de áreas abertas, como alta irradiação ou alternância de temperaturas. No entanto, uma variedade de respostas de germinação aos fatores ambientais é conhecida entre as pioneiras; algumas germinam em luz difusa ou no escuro sob temperatura constante. Um dos fatores promotores desta variedade é a massa das sementes. Parece que para as espécies com sementes muito pequenas, o est

  8. Increased TNF-alpha/IFN-gamma/IL-2 and decreased TNF-alpha/IFN-gamma production by central memory T cells are associated with protective responses against bovine tuberculosis following BCG vaccination

    Science.gov (United States)

    Central memory T cells (Tcm’s) and polyfunctional CD4 T responses contribute to vaccine-elicited protection with both human and bovine tuberculosis (TB); however, their combined role in protective immunity to TB is unclear. To address this question, we evaluated polyfunctional cytokine responses by ...

  9. Brain/MINDS: brain-mapping project in Japan

    Science.gov (United States)

    Okano, Hideyuki; Miyawaki, Atsushi; Kasai, Kiyoto

    2015-01-01

    There is an emerging interest in brain-mapping projects in countries across the world, including the USA, Europe, Australia and China. In 2014, Japan started a brain-mapping project called Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS). Brain/MINDS aims to map the structure and function of neuronal circuits to ultimately understand the vast complexity of the human brain, and takes advantage of a unique non-human primate animal model, the common marmoset (Callithrix jacchus). In Brain/MINDS, the RIKEN Brain Science Institute acts as a central institute. The objectives of Brain/MINDS can be categorized into the following three major subject areas: (i) structure and functional mapping of a non-human primate brain (the marmoset brain); (ii) development of innovative neurotechnologies for brain mapping; and (iii) human brain mapping; and clinical research. Brain/MINDS researchers are highly motivated to identify the neuronal circuits responsible for the phenotype of neurological and psychiatric disorders, and to understand the development of these devastating disorders through the integration of these three subject areas. PMID:25823872

  10. Brain/MINDS: brain-mapping project in Japan.

    Science.gov (United States)

    Okano, Hideyuki; Miyawaki, Atsushi; Kasai, Kiyoto

    2015-05-19

    There is an emerging interest in brain-mapping projects in countries across the world, including the USA, Europe, Australia and China. In 2014, Japan started a brain-mapping project called Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS). Brain/MINDS aims to map the structure and function of neuronal circuits to ultimately understand the vast complexity of the human brain, and takes advantage of a unique non-human primate animal model, the common marmoset (Callithrix jacchus). In Brain/MINDS, the RIKEN Brain Science Institute acts as a central institute. The objectives of Brain/MINDS can be categorized into the following three major subject areas: (i) structure and functional mapping of a non-human primate brain (the marmoset brain); (ii) development of innovative neurotechnologies for brain mapping; and (iii) human brain mapping; and clinical research. Brain/MINDS researchers are highly motivated to identify the neuronal circuits responsible for the phenotype of neurological and psychiatric disorders, and to understand the development of these devastating disorders through the integration of these three subject areas.

  11. Academic Profession's Challenge to the Construction of Educational Management in Japan. RIHE International Seminar Reports. No. 23

    Science.gov (United States)

    Arimoto, Akira

    2015-01-01

    Active learning is now gradually being adopted in many universities and colleges in Japan. This follows the release of the 2012 Central Council of Education (CCE) report that emphasized the need to introduce active learning and to reinforce educational management in academia. As a result, one of the most important problems in Japan's higher…

  12. A review of fast reactor programme in Japan

    International Nuclear Information System (INIS)

    1998-01-01

    This report describes the development and activities on fast reactor in Japan for the period of April 1996 - March 1997. During this period, the 30th duty cycle operation has been started in the Experimental Fast Reactor ''''Joyo''''. The cause investigation on the sodium leak incident has completed and the safety examination are being performed in the Prototype Fast Breeder Reactor ''''Monju''''. The three years design study since FY1994 on the plant optimization of the Demonstration FBR has been completed by the Japan Atomic Power Company (JAPC). Related research and development works are underway at several organizations under the discussion and coordination of the Japanese FBR R and D Steering Committee, which is composed of Power Reactor and Nuclear Fuel Development Corporation (PNC), JAPC, Japan Atomic Energy Research Institute (JAERI) and Central Research Institute of Electric Power Industry (CRIEPI). In November 1996, the Japan Atomic Energy Commission (JAEC) established a Social Gathering Meeting to discuss generally the significance of FBR development in Japan for the future. (author)

  13. Black Bear Populationatthe Mountain Road Construction Areain Chichibu, Central Japan

    OpenAIRE

    ISHIDA, Ken

    2001-01-01

    東京大学秩父演習林の中に開通した国道140号線の施設が,演習林とその周辺のツキノワグマ個体群に与える影響を評価するために,隣り合う滝川流域と入川流域において,ミツバチを誘引餌としたドラムカン製捕獲器でクマを捕獲した。捕獲個体の体重や体調を記録した。大型個体には首輪式の発信機を装着して,行動圏を調べた。1991年から1999年の主に夏季にツキノワグマの58個体を136回捕獲し,23個体の成獣に34個の電波発信機を首輪で装着して行動圏を調べた.1993年から1995年における行動圏の調査結果から,調査地で繁殖していたと推定される6~8頭の雌の成獣は7~8平方キロに1頭ていどの密度で生息していると推定された.調査地内で秋の堅果がすべて凶作の1992年に,発信機を装着した雄の1頭が直線で約9キロ離れた塩山市一ノ瀬で射殺されたことが確認され,1993年には国道周辺の滝川地域で雄の成獣が1頭も捕獲されず,1994年には同地域で未成熟の雄が捕獲されただけだった.国道140号線が施設されていたために滝川流域での雄の成獣の生息個体数の回復が遅れた可能性があると考えられた。演習林内にあるトンネルが生...

  14. Ecohydrological Responses to Hurricane Harvey across South-Central Texas a Multidisciplinary Approach of the Texas Water Observatory

    Science.gov (United States)

    Jaimes, A.; Gaur, N.; Aparecido, L. M. T.; Everett, M. E.; Knappett, P.; Lawing, M.; Majumder, S.; Miller, G. R.; Moore, G. W.; Morgan, C.; Mitra, B.; Noormets, A.; Mohanty, B.

    2017-12-01

    The unprecedented destructive hurricane Harvey struck eastern Texas from August 25th to 29th, 2017. As the hurricane moved through the region, it dropped the equivalent of one year of precipitation within a five-day period, with peak accumulations near 165 cm. Rainfall intensity and distribution varied across the region but Harris County and portions of the lower Brazos River Basin experienced devastating flooding due to high run-off and water accumulation in the built-up area. In this study, we use a multidisciplinary approach to quantify the dynamics of carbon and water flux at different spatiotemporal resolution across land types both in and outside of the path of hurricane Harvey using a combination of remote sensing and fixed monitoring platforms of the Texas Water Observatory (TWO). We used LANDSAT imagery to compute Soil Adjusted Vegetation Index, Enhanced Vegetation Index, and Normalized Difference Moisture Index. MODIS ET, GPP, and sap flow data were used in combination with eddy covariance and meteorological data from seven sites of the TWO representative of biomes ranging from low tidal salt marsh of the Gulf Coastal Plain, Shrubland, Improved Pasture, Mixed and Native Prairies, and Crop sites. We hypothesize alteration in ecohydrological characteristics across land types, which were in the path of hurricane due to changes in vegetation structure. Specifically we used trend analysis to detect structural changes in temporal dynamics of sap flow, ET, and carbon to pulse response. In addition, we monitored trace metal concentration of soil and water pores before and immediately after the hurricane in order to predict the potential of any of the toxic metal (loid)s being mobilized in the natural water resources as a function of the changes in the redox gradient. Preliminary results indicated that tree water use was reduced on average 30% below normal days. Porewater concentration of some of the metal (loid) concentration increased (Fe, Mn, Co, As, Sb, Pb

  15. Outage planning in Japan

    International Nuclear Information System (INIS)

    Nedderman, John.

    1997-01-01

    Nuclear plant operators in Japan are constrained to keep refuelling and maintenance outages to a minimum by the regulation limiting operating cycles to no longer than 13 months. Outage planning by two contrasting operators is described. Hokkaido Electric, which operates only one plant, Tomari, with two PWRs, plans to reduce outage time from the present 65 days in two stages. Detailed review of previous outage schedules has shown that a reduction to 59 days should be achievable by careful planning without any fundamental changes. The second reduction to 49 days will require such measures as relaxing water purity standards, rescheduling fuel unloading and loading shifts and speeding up eddy current testing of primary equipment by using steam generator nozzle dams. Kansai Electric, operating 11 PWRs at three plants, has scope for reducing outages at all of its units using a range of measures. Steam generator replacement in the seven oldest reactors, completed in July 1997, is by far the most significant of these and is expected to save 64 days repair time in a previous average outage time of 131 days. (UK)

  16. Radioactivity survey data in Japan

    International Nuclear Information System (INIS)

    1981-06-01

    Strontium-90 and cesium-137 in Japan were determined in rain and dry fallout, airborne dust, service water, total diet, rice, milk, vegetables, sea fish, shellfish, and seaweeds. The results were shown in tables. (J.P.N.)

  17. Nuclear power development in Japan

    International Nuclear Information System (INIS)

    Sugawara, A.

    1994-01-01

    The energy situation in Japan is briefly outlined. Vulnerability in energy structure of the country is shown by a comparison of primary energy supply patterns of Japan and Western countries. Japan's energy policy consists in reducing dependence on oil, promoting efficient use of energy and increasing use of non-fossil fuels. Nuclear power is a core of alternative energy for petroleum because of stable supply of nuclear fuel, low detrimental emissions and less dependence on the fuel. A short historical review of nuclear power development in Japan is presented. Some future issues as development of entire nuclear fuel cycle, social acceptance, reactor safety and nuclear power economics are also discussed. 6 figs. (R.T.)

  18. River profile response to normal fault growth and linkage: an example from the Hellenic forearc of south-central Crete, Greece

    Science.gov (United States)

    Gallen, Sean F.; Wegmann, Karl W.

    2017-02-01

    Topography is a reflection of the tectonic and geodynamic processes that act to uplift the Earth's surface and the erosional processes that work to return it to base level. Numerous studies have shown that topography is a sensitive recorder of tectonic signals. A quasi-physical understanding of the relationship between river incision and rock uplift has made the analysis of fluvial topography a popular technique for deciphering relative, and some argue absolute, histories of rock uplift. Here we present results from a study of the fluvial topography from south-central Crete, demonstrating that river longitudinal profiles indeed record the relative history of uplift, but several other processes make it difficult to recover quantitative uplift histories. Prior research demonstrates that the south-central coastline of Crete is bound by a large ( ˜ 100 km long) E-W striking composite normal fault system. Marine terraces reveal that it is uplifting between 0.1 and 1.0 mm yr-1. These studies suggest that two normal fault systems, the offshore Ptolemy and onshore South-Central Crete faults, linked together in the recent geologic past (ca. 0.4-1 My BP). Fault mechanics predict that when adjacent faults link into a single fault the uplift rate in footwalls of the linkage zone will increase rapidly. We use this natural experiment to assess the response of river profiles to a temporal jump in uplift rate and to assess the applicability of the stream power incision model to this setting. Using river profile analysis we show that rivers in south-central Crete record the relative uplift history of fault growth and linkage as theory predicts that they should. Calibration of the commonly used stream power incision model shows that the slope exponent, n, is ˜ 0.5, contrary to most studies that find n ≥ 1. Analysis of fluvial knickpoints shows that migration distances are not proportional to upstream contributing drainage area, as predicted by the stream power incision model

  19. Overwork-related disorders in Japan: recent trends and development of a national policy to promote preventive measures.

    Science.gov (United States)

    Yamauchi, Takashi; Yoshikawa, Toru; Takamoto, Masahiro; Sasaki, Takeshi; Matsumoto, Shun; Kayashima, Kotaro; Takeshima, Tadashi; Takahashi, Masaya

    2017-06-08

    Overwork-related disorders, such as cerebrovascular/cardiovascular diseases (CCVD) and mental disorders due to overwork, are a major occupational and public health issue worldwide, particularly in East Asian countries. This report discusses the recent trend of overwork-related disorders in Japan from the perspective of workers' compensated occupational diseases, as well as the development of a national policy for preventive measures against overwork-related disorders in Japan. Recently, the number of claimed and compensated cases of occupational mental disorders has increased substantially, particularly among young workers, as compared to those of occupational CCVD. In response to these situations and action from society, the Japanese Government passed the "Act on Promotion of Preventive Measures against Karoshi and Other Overwork-Related Health Disorders" in June 2014 to develop a national initiative towards the prevention of overwork-related disorders. Changes in the trend of overwork-related disorders in Japan under a legal foundation and an initiative by the central government should be closely monitored so that other countries can benefit from the experiences.

  20. Japan Sports Arbitration Agency (JSAA

    Directory of Open Access Journals (Sweden)

    Ekaterina P. Rusakova

    2015-12-01

    Full Text Available In this article author analyzes the activities of Japan Sports Arbitration Agency. Author considers the goals, objectives and procedure for dealing with disputes relating to the use of performance-enhancing drugs by athletes. Author study the regulation of Japan Sports Arbitration Agency, to resolve disputes relating to the use of doping, as well as the procedure for application and acceptance of its agency, the choice of arbitrators, counterclaim, protection of evidence.

  1. The photovoltaic energy in Japan

    International Nuclear Information System (INIS)

    Georgel, O.

    2005-07-01

    Today the Japan is the leader of the photovoltaic energy. The first reason of this success is an action of the government integrating subventions for the installation of photovoltaic systems and a support of the scientific research. To explain this success, the author presents the energy situation in Japan, details the national programs, the industrial sector (market, silicon needs, recycling, manufacturers, building industry) and presents the main actors. (A.L.B.)

  2. 2016 Guidelines for the management of thyroid storm from The Japan Thyroid Association and Japan Endocrine Society (First edition).

    Science.gov (United States)

    Satoh, Tetsurou; Isozaki, Osamu; Suzuki, Atsushi; Wakino, Shu; Iburi, Tadao; Tsuboi, Kumiko; Kanamoto, Naotetsu; Otani, Hajime; Furukawa, Yasushi; Teramukai, Satoshi; Akamizu, Takashi

    2016-12-30

    Thyroid