ING3 promotes prostate cancer growth by activating the androgen receptor.

Science.gov (United States)

Nabbi, Arash; McClurg, Urszula L; Thalappilly, Subhash; Almami, Amal; Mobahat, Mahsa; Bismar, Tarek A; Binda, Olivier; Riabowol, Karl T

2017-05-16

The androgen receptor (AR) is a major driver of prostate cancer, and increased AR levels and co-activators of the receptor promote the development of prostate cancer. INhibitor of Growth (ING) proteins target lysine acetyltransferase or lysine deacetylase complexes to the histone H3K4Me3 mark of active transcription, to affect chromatin structure and gene expression. ING3 is a stoichiometric member of the TIP60 lysine acetyltransferase complex implicated in prostate cancer development. Biopsies of 265 patients with prostate cancer were stained for ING3, pan-cytokeratin, and DNA. LNCaP and C4-2 androgen-responsive cells were used for in vitro assays including immunoprecipitation, western blotting, Luciferase reporter assay and quantitative polymerase chain reaction. Cell viability and migration assays were performed in prostate cancer cell lines using scrambled siRNA or siRNA targeting ING3. We find that ING3 levels and AR activity positively correlate in prostate cancer. ING3 potentiates androgen effects, increasing expression of androgen-regulated genes and androgen response element-driven reporters to promote growth and anchorage-independent growth. Conversely, ING3 knockdown inhibits prostate cancer cell growth and invasion. ING3 activates the AR by serving as a scaffold to increase interaction between TIP60 and the AR in the cytoplasm, enhancing receptor acetylation and translocation to the nucleus. Activation is independent of ING3's ability to target the TIP60 complex to H3K4Me3, identifying a previously unknown chromatin-independent cytoplasmic activity for ING3. In agreement with in vitro observations, analysis of The Cancer Genome Atlas (TCGA) data (n = 498) and a prostate cancer tissue microarray (n = 256) show that ING3 levels are higher in aggressive prostate cancers, with high levels of ING3 predicting shorter patient survival in a low AR subgroup. Including ING3 levels with currently used indicators such as the Gleason score provides more

Engineering challenges in ING

Energy Technology Data Exchange (ETDEWEB)

Wolfe, W A

1965-07-01

With the Intense Neutron Generator (ING) we intend to produce a neutron flux of 10{sup 16} n/cm{sup 2} sec. Bismuth, bombarded by 1 GeV protons, yields about 20 neutrons per proton with a heat output of 23 MeV/neutron. A circulating liquid bismuth target will dissipate about 34 MW of heat. To produce the beam we will accelerate protons in a separated orbit cyclotron. The 65 mA current will require about 70-75 MW of radio-frequency power (50-200 Mc/s). We must generate and transmit RF efficiently. In ING precise magnet-fields, resonating-cavity electric-fields and well maintained vacuum (10{sup -6} torr) will place demands on most of today's engineering technology. (author)

75 FR 16456 - Inglis Hydropower, LLC; Notice Soliciting Scoping Comments

Science.gov (United States)

2010-04-01

... Hydropower, LLC; Notice Soliciting Scoping Comments March 26, 2010. Take notice that the following...: Inglis Hydropower, LLC. e. Name of Project: Inglis Hydropower Project. f. Location: The proposed project... Commission staff intends to prepare a single Environmental Assessment (EA) for the Inglis Hydropower Project...

LACEwING: A New Moving Group Analysis Code

Energy Technology Data Exchange (ETDEWEB)

Riedel, Adric R. [Department of Astronomy, California Institute of Technology, Pasadena, CA 91125 (United States); Blunt, Sarah C.; Faherty, Jacqueline K. [Department of Astrophysics, American Museum of Natural History, New York, NY 10024 (United States); Lambrides, Erini L. [Department of Physics and Astronomy, Johns Hopkins University, Baltimore, MD 21218 (United States); Rice, Emily L. [Department of Engineering Science and Physics, The College of Staten Island, Staten Island, NY 10314 (United States); Cruz, Kelle L., E-mail: arr@astro.caltech.edu [Department of Physics and Astronomy, Hunter College, New York, NY 10065 (United States)

2017-03-01

We present a new nearby young moving group (NYMG) kinematic membership analysis code, LocAting Constituent mEmbers In Nearby Groups (LACEwING), a new Catalog of Suspected Nearby Young Stars, a new list of bona fide members of moving groups, and a kinematic traceback code. LACEwING is a convergence-style algorithm with carefully vetted membership statistics based on a large numerical simulation of the Solar Neighborhood. Given spatial and kinematic information on stars, LACEwING calculates membership probabilities in 13 NYMGs and three open clusters within 100 pc. In addition to describing the inputs, methods, and products of the code, we provide comparisons of LACEwING to other popular kinematic moving group membership identification codes. As a proof of concept, we use LACEwING to reconsider the membership of 930 stellar systems in the Solar Neighborhood (within 100 pc) that have reported measurable lithium equivalent widths. We quantify the evidence in support of a population of young stars not attached to any NYMGs, which is a possible sign of new as-yet-undiscovered groups or of a field population of young stars.

Co-Story-ing: Collaborative Story Writing with Children Who Fear

Science.gov (United States)

Pehrsson, Dale-Elizabeth

2007-01-01

This article offers a guide for using collaborative story writing (co-story-ing), an assessment technique as well as a therapeutic intervention for children who demonstrate fears, extreme shyness and difficulty in establishing relationships. Co-story-ing draws from Gardner's Mutual Story Telling Technique. Co-story-ing guides clients as they…

Modulators of inhibitor of growth (ING) family expression in development and disease.

Science.gov (United States)

Maher, Stacey K; Helbing, Caren C

2009-05-01

The inhibitor of growth (ING) gene family proteins regulate many critical cellular processes such as cell proliferation and growth, apoptosis, DNA repair, senescence, angiogenesis, and drug resistance. Their transcripts and proteins are differentially expressed in health and disease and there is evidence for developmental regulation. The vast majority of studies have characterized ING levels in the context of cancer. However, relatively little attention has been paid to the expression of ING family members in other contexts. This review summarizes the findings from human and animal model systems that provide insight into the factors influencing the expression of these important proteins. We examine the influence of cell cycle and aging as well as genotoxic stress on ING expression levels and evaluate several emerging areas of inquiry demonstrating that ING gene activity may be modulated by factors such as the p53 tumor suppressor, DNA methylation, and ING proteins themselves with external factors such as hormones, reactive oxygen species, TGFbeta signalling, and other proteins of pathological significance also influencing ING levels. We then briefly discuss the influence of post-translational modification and changes in subcellular localization as it pertains to modulation of ING expression. Understanding how ING expression is modulated represents a vital aspect of effective drug targeting strategies.

Inge Lehmann’s work materials and seismological epistolary archive

Directory of Open Access Journals (Sweden)

Erik Hjortenberg

2009-06-01

Full Text Available

The Inge Lehmann archive contains thousands of seismological work documents from Inge Lehmann’s private home. For a long time the author thought that the main concern was to keep the documents for posterity. There is now a renewed interest in Inge Lehmann, and some documents were presented in a poster at ESC Potsdam 2004, and the collection of documents were scanned and catalogued 2005-2006 at Storia Geofisica Ambiente in Bologna. Inge Lehmann (1888-1993 is famous for her discovery in 1936 of the earth’s inner core and for work on the upper mantle. A short biography is given. After her retirement in 1953 she worked at home in Denmark, and abroad in USA and in Canada. She took part in the creation of the European Seismological Commission in 1951, and in the creation of the International Seismological Centre in 1964. Inge Lehmann received many awards. Some letters from her early correspondence with Harold Jeffreys are discussed, they show how the inner core was discussed already in 1932. A few of the author’s reminiscences of Inge Lehmann are given.

Elusloom lennukiga puhkusele / Inge Parring

Index Scriptorium Estoniae

Parring, Inge

2003-01-01

Ilmunud ka: Delovõje Vedomosti 1. okt. lk. 13. Air Cargo Estonia/ACE Logisticsi müügijuht Inge Parring tutvustab elusloomade transpordivõimalusi. Vt. samas: Loomade transportimiseks vajalikud dokumendid

A Functional Role for the Epigenetic Regulator ING1 in Activity-induced Gene Expression in Primary Cortical Neurons.

Science.gov (United States)

Leighton, Laura J; Zhao, Qiongyi; Li, Xiang; Dai, Chuanyang; Marshall, Paul R; Liu, Sha; Wang, Yi; Zajaczkowski, Esmi L; Khandelwal, Nitin; Kumar, Arvind; Bredy, Timothy W; Wei, Wei

2018-01-15

Epigenetic regulation of activity-induced gene expression involves multiple levels of molecular interaction, including histone and DNA modifications, as well as mechanisms of DNA repair. Here we demonstrate that the genome-wide deposition of inhibitor of growth family member 1 (ING1), which is a central epigenetic regulatory protein, is dynamically regulated in response to activity in primary cortical neurons. ING1 knockdown leads to decreased expression of genes related to synaptic plasticity, including the regulatory subunit of calcineurin, Ppp3r1. In addition, ING1 binding at a site upstream of the transcription start site (TSS) of Ppp3r1 depends on yet another group of neuroepigenetic regulatory proteins, the Piwi-like family, which are also involved in DNA repair. These findings provide new insight into a novel mode of activity-induced gene expression, which involves the interaction between different epigenetic regulatory mechanisms traditionally associated with gene repression and DNA repair. Copyright © 2017 IBRO. Published by Elsevier Ltd. All rights reserved.

Nuclear localization signal of ING4 plays a key role in its binding to p53

International Nuclear Information System (INIS)

Zhang Xin; Wang Kesheng; Wang Zhiqin; Xu Lusheng; Wang Qingwan; Chen Fei; Wei Dongzhi; Han Zeguang

2005-01-01

ING4, a novel member of ING family, is recently reported to interact with tumor suppressor p53 and negatively regulate the cell growth with significant G2/M arrest of cell cycle in HepG2 cells through upregulation of p53-inducible gene p21. However, which region of ING4 could have contributed to the binding to p53 remains largely unclear. Herein, the GST-pulldown experiments revealed that the middle region of ING4, a potential bipartite nuclear localization signal (NLS), could be involved in the binding to p53. Furthermore, the interaction of ING4 to p53 was abrogated in vitro and in vivo when certain mutations or the entire deletion of the NLS domain occurred. More interestingly, the mutations of the NLS domain could alter the ING4 nuclear localization, disrupt the interaction of ING4 with p53, and even, deregulate the p53-inducible gene p21 in MCF-7 cells. All data indicated that the NLS domain of ING4 is essential for the binding of ING4 to p53 and the function of ING4 associated with p53

75 FR 65620 - Inglis Hydropower, LLC; Notice of Application Ready for Environmental Analysis and Soliciting...

Science.gov (United States)

2010-10-26

... Hydropower, LLC; Notice of Application Ready for Environmental Analysis and Soliciting Comments...: Inglis Hydropower, LLC. e. Name of Project: Inglis Hydropower Project. f. Location: The project would be... ready for environmental analysis at this time. l. The proposed 2.0-megawatt Inglis Hydropower Project...

ING Genes Work as Tumor Suppressor Genes in the Carcinogenesis of Head and Neck Squamous Cell Carcinoma

Directory of Open Access Journals (Sweden)

Xiaohan Li

2011-01-01

Full Text Available Head and neck squamous cell carcinoma (HNSCC is the sixth most common cancer in the world. The evolution and progression of HNSCC are considered to result from multiple stepwise alterations of cellular and molecular pathways in squamous epithelium. Recently, inhibitor of growth gene (ING family consisting of five genes, ING1 to ING5, was identified as a new tumor suppressor gene family that was implicated in the downregulation of cell cycle and chromatin remodeling. In contrast, it has been shown that ING1 and ING2 play an oncogenic role in some cancers, this situation being similar to TGF-β. In HNSCC, the ING family has been reported to be downregulated, and ING translocation from the nucleus to the cytoplasm may be a critical event for carcinogenesis. In this paper, we describe our recent results and briefly summarize current knowledge regarding the biologic functions of ING in HNSCC.

Electro-economic, environmental and social consequences in the efficient abatement of a hydroelectric plant (C. H. Santa Rosa, CFE-ACO); Consecuencias electro-economicas, ambientales y sociales del abatimiento eficiente de una central hidroelectrica (C. H. Santa Rosa, CFE-ACO)

Energy Technology Data Exchange (ETDEWEB)

Narvaez Perez, Camilo; Garcia Conejo, Dante Aristoteles [Comision Federal de Electricidad, Centro Nacional de Control de Energia, Area de Control Occidental, Zapopan, Jalisco (Mexico)]. E-mail: camilo.narvaez@cfe.gob.mx; camilo.narvaez@univa.mx; Narvaez Perez, Claudia Universidad de Guadalajara, Zapopan, Jalisco [Mexico]). E-mail: claudia_narvaez@hotmail.com; Blanco Gomez, Cesar Eduardo [Comision Federal de Electricidad, Centro Nacional de Control de Energia, Area de Control Occidental, Zapopan, Jalisco (Mexico)

2013-03-15

Renewable energy systems, like hydroelectric generation system gives electric energy, in reliable economic, it takes care with environment, and growths the society, if the hydroelectric dam is suitably drained in non rainy season, if we consider, flow rate in its river, rain, thunderstorms and floods, dam's size, load shape per day, generators capacity unit and the flow in turbines, generating units maintenance and other necessities like irrigation crops in farms. In this research we propose a new methodology about hydroelectric dam drained in non rainy season. But in rainy season, you can consider this methodology with few changes and you would obtain satisfactory results. The methodology is used since 2010 in the Area de Control Occidental in the Comision Federal de Electricidad with results compared with data from previous years, in which different methodologies were applied. [Spanish] Los sistemas de energias renovables, como los complejos hidroelectricos impactan de manera electrica, economica, ambiental y social, siempre y cuando se realice adecuadamente el abatimiento de la presa en el estiaje, considerando, el aporte del cauce, las lluvias aun siendo escasas, el tamano del embalse, la demanda horaria de la carga abastecida, el tamano de los generadores y su gasto turbinado, los mantenimientos de las unidades, las necesidades hidraulicas aguas abajo y demas imponderantes. En esta investigacion se propone una metodologia de abatimiento de presas de centrales hidroelectricas en estiaje. Y para tiempo de lluvias se aplica la metodologia con variantes pequenas y con resultados satisfactorios. La metodologia es utilizada desde el 2010 en el Area de Control Occidental de la Comision Federal de Electricidad, con resultados comparados con los datos de los anos anteriores, en los cuales se aplicaron metodologias diversas.

De quels ingénieurs parle-t-on ? Situation et trajectoires des ingénieurs des grandes écoles. Le cas du Maroc

Directory of Open Access Journals (Sweden)

Pierre Vermeren

2009-05-01

Full Text Available Cet article est consacré au cas des « ingénieurs de conception » marocains, formés la plupart du temps dans les grandes écoles françaises. Cette fraction des ingénieurs marocains (dont la majorité est formée dans les écoles d'ingénieurs du Maroc n'est pas loin de constituer une véritable aristocratie de fonction. Ce phénomène illustre la structure sociale très inégalitaire du Maroc et la stratification opérée par la monarchie (le Makhzen pour sélectionner ses élites, qui sont aujourd'hui des élites à la fois technocratiques et sociales. Cette domination des « technocrates » sur l'appareil d'Etat marocain, analysée ici à travers des publics étudiants de grandes écoles, s'accompagne de l'émergence d'une contre-élite sociale de contestation. Les écoles d'ingénieurs de second rang, peuplées par les éléments des classes moyennes, ont été le premier terreau des mouvements islamistes en milieu universitaire. Elles produisent aujourd'hui une contre-élite politique et sociale qui piétine aux portes du vrai pouvoir.

ING1 and 5-azacytidine act synergistically to block breast cancer cell growth.

Directory of Open Access Journals (Sweden)

Satbir Thakur

Full Text Available Inhibitor of Growth (ING proteins are epigenetic "readers" that recognize trimethylated lysine 4 of histone H3 (H3K4Me3 and target histone acetyl transferase (HAT and histone deacetylase (HDAC complexes to chromatin.Here we asked whether dysregulating two epigenetic pathways with chemical inhibitors showed synergistic effects on breast cancer cell line killing. We also tested whether ING1 could synergize better with chemotherapeutics that target the same epigenetic mechanism such as the HDAC inhibitor LBH589 (Panobinostat or a different epigenetic mechanism such as 5-azacytidine (5azaC, which inhibits DNA methyl transferases. Simultaneous treatment of breast cancer cell lines with LBH589 and 5azaC did not show significant synergy in killing cells. However, combination treatment of ING1 with either LBH589 or 5azaC did show synergy. The combination of ING1b with 5azaC, which targets two distinct epigenetic mechanisms, was more effective at lower doses and enhanced apoptosis as determined by Annexin V staining and cleavage of caspase 3 and poly-ADP-ribose polymerase (PARP. ING1b plus 5azaC also acted synergistically to increase γH2AX staining indicating significant levels of DNA damage were induced. Adenoviral delivery of ING1b with 5azaC also inhibited cancer cell growth in a murine xenograft model and led to tumor regression when viral concentration was optimized in vivo.These data show that targeting distinct epigenetic pathways can be more effective in blocking cancer cell line growth than targeting the same pathway with multiple agents, and that using viral delivery of epigenetic regulators can be more effective in synergizing with a chemical agent than using two chemotherapeutic agents. This study also indicates that the ING1 epigenetic regulator may have additional activities in the cell when expressed at high levels.

Idiopathic nodular glomerulosclerosis (ING) in an African American (AA) man with hepatitis C.

Science.gov (United States)

Onteddu, Nirmal K; Duggirala, Jayasri; Reddy, Anand C

2018-05-18

Idiopathic nodular glomerulosclerosis (ING) in a non-diabetic patient is uncommon. Nodular glomerulosclerosis is hallmark sign of diabetic nephropathy. ING is a very rare clinicopathological disease associated with smoking, obesity and hypertension, chronic obstructive pulmonary disease and metabolic syndrome. A 68-year-old non-obese African American man with hypertension, smoking and history of hepatitis C presented to the clinic with progressive worsening of lower extremity oedema and declining renal function over few months. Renal biopsy demonstrated nodular glomerulosclerosis. In this case, ING is hypothesised to be associated with hepatitis C along with smoking and hypertension (HTN). We present this case to speculate the existence of yet unknown aetiologies of ING. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Some neutron measurements with simulated ING targets

Energy Technology Data Exchange (ETDEWEB)

Walker, J

1966-07-01

Thermal neutron fluxes in the vicinity of a simulated Intense Neutron Generator target have been measured using Mn and Au foils, and a small BF{sub 3} detector. The target was a Pb cylinder either 4-inch or 8-inch in diameter with a 1.2 g Ra-Be neutron source at its centre. This was centrally mounted in a 5' diam. x 5' high tank which was filled with either H{sub 2}O or D{sub 2}O moderator. Various gaps and absorbing annuli were placed around the target, and air-filled aluminum 'beam tubes' were mounted radially or tangentially from the target to simulate typical ING conditions. The measured thermal neutron fluxes were less than calculated at all radii. The single-age computation clearly gives large errors at large radii, but the multi-energy approach seems to give a useful indication of the thermal flux distribution in spite of the extreme simplicity of the model. The fall in measured fluxes at small radii in both D{sub 2}O and H{sub 2}O is most likely caused by absorption in the target material which is not allowed for in the computational model. (author)

Some neutron measurements with simulated ING targets

International Nuclear Information System (INIS)

Walker, J.

1966-01-01

Thermal neutron fluxes in the vicinity of a simulated Intense Neutron Generator target have been measured using Mn and Au foils, and a small BF 3 detector. The target was a Pb cylinder either 4-inch or 8-inch in diameter with a 1.2 g Ra-Be neutron source at its centre. This was centrally mounted in a 5' diam. x 5' high tank which was filled with either H 2 O or D 2 O moderator. Various gaps and absorbing annuli were placed around the target, and air-filled aluminum 'beam tubes' were mounted radially or tangentially from the target to simulate typical ING conditions. The measured thermal neutron fluxes were less than calculated at all radii. The single-age computation clearly gives large errors at large radii, but the multi-energy approach seems to give a useful indication of the thermal flux distribution in spite of the extreme simplicity of the model. The fall in measured fluxes at small radii in both D 2 O and H 2 O is most likely caused by absorption in the target material which is not allowed for in the computational model. (author)

ING status report July 1967

Energy Technology Data Exchange (ETDEWEB)

Church, T G

1967-07-01

Evolution of ING from initial concept to advanced systems and the interplay between participating disciplines are illustrated in Fig. 1.2. Anticipated requirements for intense continuous fluxes of thermal neutrons set the initial goal and dictated the scale and other guidelines of the system including the desired completion date. While neutron applications were given prime consideration in conceptual planning, much wider fields of research, both pure and applied, would benefit from the facility now being studied. (author)

ING status report July 1967

International Nuclear Information System (INIS)

Church, T.G.

1967-01-01

Evolution of ING from initial concept to advanced systems and the interplay between participating disciplines are illustrated in Fig. 1.2. Anticipated requirements for intense continuous fluxes of thermal neutrons set the initial goal and dictated the scale and other guidelines of the system including the desired completion date. While neutron applications were given prime consideration in conceptual planning, much wider fields of research, both pure and applied, would benefit from the facility now being studied. (author)

introduction à l'ingénierie documentaire et aux sciences de l'information

OpenAIRE

Guyot, Brigitte

2011-01-01

polycopié introductif pour la formation chef de projet en ingénierie documentaire, Cnam; introductory course on documentary engineering: definition, applications, objects, process, actors of the market, historical elements; cours introductif à l'ingénierie documentaire : positionnement, objets, processus, acteurs du marché, repères historiques

Immediate relation of ING to fast breeder reactor programs

Energy Technology Data Exchange (ETDEWEB)

Lewis, W B

1969-07-01

The future large-scale use of nuclear energy is linked in the United States and other major countries to their fast breeder reactor development. Very serious basic problems have been discovered within the last two years, limiting the life in the high fast neutron flux at appropriate temperatures of materials, in particular of metals suitable for fuel cladding in sodium coolant. There is therefore a most urgent need for materials testing facilities under controlled conditions of temperature and neutron flux at sufficiently high ratings to match or surpass those required in commercially competitive fast breeder reactors. None of the test facilities yet planned for 1976 or sooner in the western world appears to match these conditions. The problem is mainly the difficulty of providing the high neutron flux effectively continuously. The spallation reaction in heavy elements was chosen as the basis of ING - the intense neutron generator, because it is the only known reaction that promises a fast neutron source density that is higher than can be controlled from the fission process. It is suggested that several countries will wish to consider urgently whether they should also explore the spallation reaction for the purpose of a fast neutron irradiation test facility. In view of the discontinuance of the ING project in Canada a favourable opportunity will exist over the next few months 10 obtain from Canada by direct personal contact details of the significant study that has been carried on for ING over the last five years. In the event that satisfactory materials are established within the lifetime of the spallation facilities they may continue to be used for the production of selected isotopes more profitably produced in high neutron fluxes. The facilities may be also used for the desirable preirradiation of thorium reactor fuel. The other research purposes planned for ING could also be served. (author)

Immediate relation of ING to fast breeder reactor programs

International Nuclear Information System (INIS)

Lewis, W.B.

1969-01-01

The future large-scale use of nuclear energy is linked in the United States and other major countries to their fast breeder reactor development. Very serious basic problems have been discovered within the last two years, limiting the life in the high fast neutron flux at appropriate temperatures of materials, in particular of metals suitable for fuel cladding in sodium coolant. There is therefore a most urgent need for materials testing facilities under controlled conditions of temperature and neutron flux at sufficiently high ratings to match or surpass those required in commercially competitive fast breeder reactors. None of the test facilities yet planned for 1976 or sooner in the western world appears to match these conditions. The problem is mainly the difficulty of providing the high neutron flux effectively continuously. The spallation reaction in heavy elements was chosen as the basis of ING - the intense neutron generator, because it is the only known reaction that promises a fast neutron source density that is higher than can be controlled from the fission process. It is suggested that several countries will wish to consider urgently whether they should also explore the spallation reaction for the purpose of a fast neutron irradiation test facility. In view of the discontinuance of the ING project in Canada a favourable opportunity will exist over the next few months 10 obtain from Canada by direct personal contact details of the significant study that has been carried on for ING over the last five years. In the event that satisfactory materials are established within the lifetime of the spallation facilities they may continue to be used for the production of selected isotopes more profitably produced in high neutron fluxes. The facilities may be also used for the desirable preirradiation of thorium reactor fuel. The other research purposes planned for ING could also be served. (author)

The inhibitor of growth protein 5 (ING5 depends on INCA1 as a co-factor for its antiproliferative effects.

Directory of Open Access Journals (Sweden)

Feng Zhang

Full Text Available The proteins of the Inhibitor of Growth (ING family are involved in multiple cellular functions such as cell cycle regulation, apoptosis, and chromatin remodeling. For ING5, its actual role in growth suppression and the necessary partners are not known. In a yeast-two-hybrid approach with human bone marrow derived cDNA, we identified ING5 as well as several other proteins as interaction partners of Inhibitor of cyclin A1 (INCA1 that we previously characterized as a novel interaction partner of cyclin A1/CDK2. ING5 expression in leukemic AML blasts was severely reduced compared to normal bone marrow. In line, ING5 inhibited bone marrow colony formation upon retroviral transduction. However, Inca1(-/- bone marrow colony formation was not suppressed by ING5. In murine embryonic fibroblast (MEF cells from Inca1(+/+ and Inca1(-/- mice, overexpression of ING5 suppressed cell proliferation only in the presence of INCA1, while ING5 had no effect in Inca1(-/- MEFs. ING5 overexpression induced a delay in S-phase progression, which required INCA1. Finally, ING5 overexpression enhanced Fas-induced apoptosis in Inca1(+/+ MEFs, while Inca1(-/- MEFs were protected from Fas antibody-induced apoptosis. Taken together, these results indicate that ING5 is a growth suppressor with suppressed expression in AML whose functions depend on its interaction with INCA1.

78 FR 39023 - ING Investments, LLC, et al.;

Science.gov (United States)

2013-06-28

... SECURITIES AND EXCHANGE COMMISSION [Investment Company Act Release No. 30566; File No. 812-14111] ING Investments, LLC, et al.; Notice of Application June 24, 2013. AGENCY: Securities and Exchange Commission (``Commission''). ACTION: Notice of an application under section 6(c) of the Investment Company...

Entre culture générale et enjeux des métiers d'ingénieur : la diversité des enseignements en sciences humaines et sociales à l'École Centrale de Lyon

Directory of Open Access Journals (Sweden)

Hourcade Nicolas

2014-01-01

Full Text Available Ce texte analyse le développement d'enseignements en sciences humaines et sociales à l'École Centrale de Lyon, établissement formant des ingénieurs généralistes. Très limités au milieu des années 1990, les cours de SHS constituent aujourd'hui un aspect significatif de la formation. La première spécificité de cette offre pédagogique est de comprendre un nombre relativement important de cours obligatoires, complétés par des activités optionnelles. Sa seconde particularité est de traiter de thématiques générales à côté de contenus classiques liés aux enjeux des métiers d'ingénieur. Sa troisième caractéristique est de s'appuyer sur une implication de l'équipe SHS dans les activités professionnalisantes, tout en les séparant des enseignements disciplinaires. Enfin, l'inscription des SHS à l'ECL s'effectue plus par l'enseignement que par la recherche, chaque membre de l'équipe étant rattaché à un laboratoire extérieur différent.

The 'Techniques de l'ingénieur' available online at CERN!

CERN Multimedia

2001-01-01

Those already familiar with 'Techniques de l'ingénieur' will be delighted. This engineering technology database widely known among French-speaking engineers and technicians can now be consulted online from the CERN Intranet until the end of the summer. To access this database of reference articles in French, all you need to do is go to the CERN Library's Web pages (http://library.cern.ch) and click on the 'Techniques de l'ingénieur' link under the 'News' heading. The Library will be monitoring the use of the database for a couple of months, at the end of which an access licence may be negotiated. Don't hesitate to use it because the decision whether or not to purchase it will depend on the extent to which it is used. The Library is seeking partners within the Laboratory to finance the purchase if it is decided to go ahead with it. Contributions from the CERN community are therefore welcome. For those who are not yet familiar with it, the 'Techniques de l'ingénieur' database ...

77 FR 58375 - Inglis Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

Science.gov (United States)

2012-09-20

... Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications On May 18, 2012, Inglis Hydropower, LLC filed an... study the feasibility of a hydropower project located at the Inglis Bypass Channel, located on the...

Central American Flying Weather

Science.gov (United States)

1985-12-01

CEILING; VISIBILITY; WIND, PRECIPITATIDNc’--." HAZE, SMOKE, TEMPORALE ; MOUNTAIN WAVE; MILITARY METEOROLOGY. 4k- / ’A. bstract; Asummary of~ing weather...1 The " Temporale " ....................................1 Mountain Waves ......................I...............1 Severe Thunderstorms...charts. The for any part of Central America lies in having: Tactical Pilota.e Chart series , produced by the Df -.nse Mapping Agency, is * A good, basic

Pour une ingénierie des Environnements Informatiques pour l'Apprentissage Humain

OpenAIRE

Tchounikine , Pierre

2002-01-01

Nous proposons dans cet article une réflexion sur la notion d'ingénierie des EIAH (Environnements Informatiques pour l'Apprentissage Humain). Nous posons tout d'abord une définition de l'ingénierie des EIAH : travaux visant à définir des éléments de méthodes et de techniques reproductibles et/ou réutilisables facilitant la mise en place (conception – réalisation – expérimentation – évaluation - diffusion) d'environnements de formation ou d'apprentissage (dans leur articulation avec les dispos...

The ING Seismic Network Databank (ISND : a friendly parameters and waveform database

Directory of Open Access Journals (Sweden)

G. Smriglio

1995-06-01

Full Text Available he Istituto Nazionale di Geofisica (ING Seismic Network Database (ISND includes over 300000 arrivaI times of Italian, Mediterranean and teleseismic earthquakes from 1983 to date. This database is a useful tool for Italian and foreign seismologists ( over 1000 data requests in the first 6 months of this year. Recently (1994 the ING began storing in the ISND, the digital waveforms associated with arri,Tal times and experimen- tally allowed users to retrieve waveforms recorded by the ING acquisition system. In this paper we describe the types of data stored and the interactive and batch procedures available to obtain arrivaI times and/or asso- ciated waveforms. The ISND is reachable via telephone line, P.S.I., Internet and DecNet. Users can read and send to their E-mail address alI selected earthquakes locations, parameters, arrivaI times and associated digital waveforms (in SAC, SUDS or ASCII format. For r;aedium or large amounts of data users can ask to receive data by means of magnetic media (DAT, Video 8, floppy disk.

How Inge Lehmann Discovered the Inner Core of the Earth

Science.gov (United States)

Rousseau, Christiane

2013-01-01

The mathematics behind Inge Lehmann's discovery that the inner core of the Earth is solid is explained using data collected around the Earth on seismic waves and their travel time through the Earth.

76 FR 45303 - ING Asia Pacific High Dividend Equity Income Fund, et al.; Notice of Application

Science.gov (United States)

2011-07-28

... Premium Opportunity Fund (``IGA''); ING Global Equity Dividend and Premium Opportunity Fund (``IGD''); ING... Exchange. PRT has also issued preferred shares. Each Current Fund reserves the right to issue preferred... market price and its net asset value per common share (``NAV'')) and the relationship between such Fund's...

Management practices and production constraints of central ...

African Journals Online (AJOL)

management practices of central highland goats and their major constraints. ... tance to improve the goat production potential and livelihood of the farmers in the study ... ing the productivity and income from keeping goats, there is a study gap in ..... and day time, possibly increasing the chance of getting contagious diseases.

75 FR 10230 - Inglis Hydropower, LLC; Notice of Application Accepted for Filing and Soliciting Motions To...

Science.gov (United States)

2010-03-05

... Hydropower, LLC; Notice of Application Accepted for Filing and Soliciting Motions To Intervene and Protests... No.: P-12783-003. c. Date filed: July 22, 2009. d. Applicant: Inglis Hydropower, LLC. e. Name of Project: Inglis Hydropower Project. f. Location: The proposed project would be located at the existing...

Efficacy of combining ING4 and TRAIL genes in cancer-targeting gene virotherapy strategy: first evidence in preclinical hepatocellular carcinoma.

Science.gov (United States)

Galal El-Shemi, A; Mohammed Ashshi, A; Oh, E; Jung, B-K; Basalamah, M; Alsaegh, A; Yun, C-O

2018-01-01

Current treatments of hepatocellular carcinoma (HCC) are ineffective and unsatisfactory in many aspects. Cancer-targeting gene virotherapy using oncolytic adenoviruses (OAds) armed with anticancer genes has shown efficacy and safety in clinical trials. Nowadays, both inhibitor of growth 4 (ING4), as a multimodal tumor suppressor gene, and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), as a potent apoptosis-inducing gene, are experiencing a renaissance in cancer gene therapy. Herein we investigated the antitumor activity and safety of mono- and combined therapy with OAds armed with ING4 (Ad-ΔB/ING4) and TRAIL (Ad-ΔB/TRAIL) gene, respectively, on preclinical models of human HCC. OAd-mediated expression of ING4 or TRAIL transgene was confirmed. Ad-ΔB/TRAIL and/or Ad-ΔB/ING4 exhibited potent killing effect on human HCC cells (HuH7 and Hep3B) but not on normal liver cells. Most importantly, systemic therapy with Ad-ΔB/ING4 plus Ad-ΔB/TRAIL elicited more eradicative effect on an orthotopic mouse model of human HCC than their monotherapy, without causing obvious overlapping toxicity. Mechanistically, Ad-ΔB/ING4 and Ad-ΔB/TRAIL were remarkably cooperated to induce antitumor apoptosis and immune response, and to repress tumor angiogenesis. This is the first study showing that concomitant therapy with Ad-ΔB/ING4 and Ad-ΔB/TRAIL may provide a potential strategy for HCC therapy and merits further investigations to realize its possible clinical translation.

Ingénierie des compétences et scénarisation pédagogique

Directory of Open Access Journals (Sweden)

Josianne Basque

2007-01-01

Full Text Available Cet article décrit un processus d’ingénierie éducative orienté compétences d’une activité d’autoévaluation et son intégration à un scénario pédagogique de cours à distance. Cette description est documentée par deux cas d’application dans un contexte de formation universitaire à distance. Le travail d’ingénierie utilise une approche en autogestion des compétences pour concevoir l’activité d’autoévaluation et l’instrumentaliser avec l’outil logiciel web d’autodiagnostic des compétences, appelé Compétences+. Cet acte d’ingénierie pédagogique porte l’attention de l’enseignant-concepteur sur une démarche centrée sur l’apprentissage dans une perspective d’autogestion des connaissances et de sa validation dans un usage en contexte isomorphe à une situation professionnelle réelle.

Radioprotection et ingénierie nucléaire

CERN Document Server

2006-01-01

Le développement de l'énergie nucléaire repose sur deux piliers essentiels : la sûreté nucléaire, qui concerne la machine, et la radioprotection, qui se préoccupe des hommes. Construit de manière fiable, un réacteur nucléaire se doit d'irradier le moins possible ses opérateurs et conduire à un impact très faible pour les populations avoisinantes. Tout cela est soumis à des règles strictes, élaborées au niveau international, et qui ne tolèrent aucun écart. Les ingénieurs qui ont à concevoir, construire et conduire ces machines doivent maîtriser les règles de protection : cet ouvrage leur est destiné. La radioprotection, si elle se fonde principalement sur des bases scientifiques, intègre également une dimension sociétale exigeante. Ces activités sont en effet sous le regard critique et permanent de nos concitoyens, qui exigent des acteurs de cette industrie une maîtrise totale de la radioprotection ; un ingénieur qui ne connaîtrait pas la genèse de la radioprotection, ses règle...

Loyola University distingue al Ing. Martínez

OpenAIRE

Lezcano, Liseth

2011-01-01

El Ing. Axel Martínez, Director de Recursos Humanos de la Universidad Tecnológica de Panamá (UTP), recibió un reconocimiento que le hizo el Instituto de Recursos Humanos y Relaciones Industriales de Loyola University Chicago (LUC), como egresado destacado del Programa de Maestría en Recursos Humanos, por la prestigiosa carrera académica y por sus éxitos profesionales en un importante ambiente académico.

Cooperation of Ad-hING4 and 125I seed in tumor-suppression on human pancreatic cancer xenograft in nude mice

International Nuclear Information System (INIS)

Zhai Hongyan; Fa Yihua; Su Chenghai; Yang Jicheng; Sheng Weihua; Xie Yufeng

2009-01-01

This work is to investigate the combined tumor-suppression effect of Adenovirus-mediated human ING4 (Ad-hING4) and 125 I seed on human pancreatic cancer xenograft and the possible mechanisms. Ad-hING4 recombinant adenovirus vector was transected into QBI-293A cells and high titre adenovirus was obtained. Subcutaneous tumor models were established with 25 nude mice with human pancreatic cancer cell line PANC-1. They were randomly divided into 5 groups: PBS control group, Ad carrier group, 125 I seed brachytherapy group, Ad-hING4 gene treatment group, combined 125 I seed and Ad-hING4 group. The tumor volumes were measured every 5 days after treatment, and were sacrificed on the 20th day. The tumors were measured and weighed to determine the ratio of tumor-suppression and Jin-Shi q value. Morphological changes of tumor cells,the tissue injury and apoptotic index AI were examined on pathological sections. MVD, Survivin and Caspase3 were tested in immunohistochemistry. The results show that the tumor-suppressive ratio of the 125 I seed group, Ad-hING4 group, combined treatment group were,respectively, 34.19%(P 0.05). It can be concluded that 125 I seed and Ad-hING4 inhibit the growth of PANC-1 pancreatic cancer on nude mice significantly. These indicate a synergy of the combined treatments in tumor-suppression and Ad-hING4 is a promising novel radiosensitizer. The mechanisms of tumor-suppressive may be multi-pathways such as down-regulation the expression of Survivin and up-regulation the expression of Caspase3 to induce apoptosis and inhibit angiogenesis. (authors)

Linnagaleriis avati ülevaatenäitus 'Pärnu sügis 98' / Leonhard Lapin, Inge Teder ; interv. Tiiu Leis

Index Scriptorium Estoniae

Lapin, Leonhard, 1947-

1998-01-01

14. okt avati Pärnu Linnagaleriis Pärnu kunstnike maalinäitus, töid valisid Kunstiakadeemia õppejõud Leonhard Lapin ja Inge Teder ning Linnagalerii nõukogu liige Feliks Krapp. Intervjuu L. Lapini ja Inge Tederiga.

Detennination Qf Optimuni on-fann Seed Pri~ing Time for Maize ...

African Journals Online (AJOL)

maize seed to on-far111 priming is an important development which can be used to improve ... Key words: semi-arid: crop establishment; sorghum; maize: on-farm seed priming; Zimbapwe. ... faster growth and higher yield after seed prim-, ing.

FoRSIC : De l'ingénierie des compétences à l'ingénierie des connaissances.

OpenAIRE

Ertzscheid , Olivier; Link-Pezet , Jo; Lacombe , Elisabeth

2002-01-01

FoRSIC [1] est un dispositif d'ingénierie des connaissances, qui s'ancre dans le champ de la formation à la recherche documentaire. Après avoir précisé le contexte théorique qui le sous-tend, nous décrirons ici les méthodologies qui nous ont permis de faire émerger des représenta-tions structurantes et partageables de ce domaine, à l'aide d'une ontologie des compétences docu-mentaires que nous relions au réseau sémantique du modèle de domaine.

SCFJFK is a bona fide E3 ligase for ING4 and a potent promoter of the angiogenesis and metastasis of breast cancer

Science.gov (United States)

Yan, Ruorong; He, Lin; Li, Zhongwu; Han, Xiao; Liang, Jing; Si, Wenzhe; Chen, Zhe; Li, Lei; Xie, Guojia; Li, Wanjin; Wang, Peiyan; Lei, Liandi; Zhang, Hongquan; Pei, Fei; Cao, Dengfeng

2015-01-01

Loss of function/dysregulation of inhibitor of growth 4 (ING4) and hyperactivation of NF-κB are frequent events in many types of human malignancies. However, the molecular mechanisms underlying these remarkable aberrations are not understood. Here, we report that ING4 is physically associated with JFK. We demonstrated that JFK targets ING4 for ubiquitination and degradation through assembly of an Skp1–Cul1–F-box (SCF) complex. We showed that JFK-mediated ING4 destabilization leads to the hyperactivation of the canonical NF-κB pathway and promotes angiogenesis and metastasis of breast cancer. Significantly, the expression of JFK is markedly up-regulated in breast cancer, and the level of JFK is negatively correlated with that of ING4 and positively correlated with an aggressive clinical behavior of breast carcinomas. Our study identified SCFJFK as a bona fide E3 ligase for ING4 and unraveled the JFK–ING4–NF-κB axis as an important player in the development and progression of breast cancer, supporting the pursuit of JFK as a potential target for breast cancer intervention. PMID:25792601

La sauvegarde des grandes oeuvres de l'ingénierie du XXème siècle

CERN Document Server

Graf, Franz

2016-01-01

Consacré à la sauvegarde des grandes oeuvres de l’ingénierie du XXe siècle, ce premier numéro des Cahiers du TSAM explore le devenir de certaines des plus remarquables et emblématiques structures en béton du siècle passé. A travers les fi gures d’héroïques constructeurs, il interroge l’héritage construit des ingénieurs, convoquant les plus audacieux d’entre eux (Freyssinet, Isler, Maillart, Nervi, Vierendeel, etc.). Alors que la sauvegarde de l’architecture du XXe siècle s’est récemment constituée en discipline à part entière, la préservation des ouvrages de l’ingénierie de cette période est encore balbutiante. Considérés trop souvent sous le seul point de vue de la sécurité ou de la maintenance, ces ouvrages s’avèrent parfois de véritables chefs-d’oeuvre, jalons d’un «art de l’ingénieur» à la frontière entre performance technique et beauté plastique. Ces cahiers sont donc l’occasion d’initier, à l’appui d’exemples et de projets de sauvegarde con...

77 FR 74245 - ING Investments, LLC, et al.; Notice of Application

Science.gov (United States)

2012-12-13

... SECURITIES AND EXCHANGE COMMISSION [Investment Company Act Release No. 30295; 812-14013] ING Investments, LLC, et al.; Notice of Application December 6, 2012. AGENCY: Securities and Exchange Commission (``Commission''). ACTION: Notice of application for an order under section 17(d) of the Investment Company Act...

SCF(JFK) is a bona fide E3 ligase for ING4 and a potent promoter of the angiogenesis and metastasis of breast cancer.

Science.gov (United States)

Yan, Ruorong; He, Lin; Li, Zhongwu; Han, Xiao; Liang, Jing; Si, Wenzhe; Chen, Zhe; Li, Lei; Xie, Guojia; Li, Wanjin; Wang, Peiyan; Lei, Liandi; Zhang, Hongquan; Pei, Fei; Cao, Dengfeng; Sun, Luyang; Shang, Yongfeng

2015-03-15

Loss of function/dysregulation of inhibitor of growth 4 (ING4) and hyperactivation of NF-κB are frequent events in many types of human malignancies. However, the molecular mechanisms underlying these remarkable aberrations are not understood. Here, we report that ING4 is physically associated with JFK. We demonstrated that JFK targets ING4 for ubiquitination and degradation through assembly of an Skp1-Cul1-F-box (SCF) complex. We showed that JFK-mediated ING4 destabilization leads to the hyperactivation of the canonical NF-κB pathway and promotes angiogenesis and metastasis of breast cancer. Significantly, the expression of JFK is markedly up-regulated in breast cancer, and the level of JFK is negatively correlated with that of ING4 and positively correlated with an aggressive clinical behavior of breast carcinomas. Our study identified SCF(JFK) as a bona fide E3 ligase for ING4 and unraveled the JFK-ING4-NF-κB axis as an important player in the development and progression of breast cancer, supporting the pursuit of JFK as a potential target for breast cancer intervention. © 2015 Yan et al.; Published by Cold Spring Harbor Laboratory Press.

BE-ing @Work: Wearables and Presence of Mind in the Workplace

Science.gov (United States)

Forbes Oste, Heidi

2016-01-01

Expectations and demands in the changing contemporary workplace are driven by emergent technologies. Ubiquitous in nature, they are designed to enhance human and organization potential. These technologies provide access to information and connection at all times. They are increasingly reliant on human relationships and connection. BE-ing one's…

Inges Kindlustus kukkus kahjumisse. Kindlustushindade alandamata jätmine viis miinusesse / Kadrin Karner

Index Scriptorium Estoniae

Karner, Kadrin

2011-01-01

Inges Kindlustuse kahjumi põhjustas kõrgema hinnataseme säilitamine ning juhatuse liikmele välja makstud märkimisväärne tasu. Konkurentide RSA Kindlustus, Ergo Kindlustuse AS ja IF Kindlustus majandustulemused

Loïc Brémaud, Catherine Guillaumin, L'archipel de l'ingénierie de la formation. Transformations, recompositions

OpenAIRE

Wahl, Elodie

2011-01-01

L'ouvrage L'archipel de l'ingénierie de la formation est la publication des actes d'un colloque qui s'est tenu à l'Université de Rennes 2 en janvier 2009. Le colloque comptait 22 intervenants, l'ouvrage est conséquent, et les articles sont très variés, tant par les perspectives adoptées, que par leurs formes ou leurs contenus. L'ouvrage se divise en trois grandes parties : la première traite de l'évolution de l'ingénierie de la formation, la seconde des nouvelles pratiques d'ingénierie, et la...

BRÉMAUD Loïc & GUILLAUMIN Catherine (dir.). L’archipel de l’ingénierie de formation. Transformations, recompositions

OpenAIRE

Lavielle-Gutnik, Nathalie

2011-01-01

Cet ouvrage fait suite à un colloque éponyme associant les universités de Rennes 2, Tours et Nantes célébrant les vingt ans du Master SIFA (Stratégie et ingénierie en formation d’adultes). Le projet intellectuel que nourrit cet ouvrage est de reconsidérer les évolutions actuelles du champ de l’ingénierie de la formation. Son intérêt est moins d’identifier les pratiques d’ingénierie de formation, ce qu’il permet toutefois clairement de réaliser, que d’engager un véritable travail de modélisati...

On Mathematicians' Proof Skimming: A Reply to Inglis and Alcock

Science.gov (United States)

Weber, Keith; Mejia-Ramos, Juan Pablo

2013-01-01

n a recent article, Inglis and Alcock (2012) contended that their data challenge the claim that when mathematicians validate proofs, they initially skim a proof to grasp its main idea before reading individual parts of the proof more carefully. This result is based on the fact that when mathematicians read proofs in their study, on average their…

N-methyl-N-nitro-N-nitrosoguanidine-mediated ING4 downregulation contributed to the angiogenesis of transformed human gastric epithelial cells.

Science.gov (United States)

Chen, Yansu; Fu, Rui; Xu, Mengdie; Huang, Yefei; Sun, Guixiang; Xu, Lichun

2018-04-15

Angiogenesis is associated with the progression and mortality of gastric cancer. Epidemiological evidences indicate that long-term N-nitroso compounds (NOCs) exposure predominantly contributes to the mortality of gastric cancer. Therefore, further reduced mortality of gastric cancer demands to explore the exact mechanisms of NOCs induced angiogenesis. As a tumor suppressor gene, inhibitor of growth protein 4 (ING4) plays an important role in pathological angiogenesis. In this study, we will investigate ING4 expression level in human gastric epithelial cells after the long-term low dose exposure of N-methyl-N-nitro-N-nitrosoguanidine (MNNG) and the pathological impact of MNNG-reduced ING4 on angiogenesis of transformed cells. The soft agar colony formation assay, Western blotting, immunofluorescence and wound healing assay were used to evaluate the characteristics of transformed cells. HUVEC growth and tube formation assays were performed to test the angiogenic abilities. EMSA, luciferase reporter gene assay, real-time PCR and Western blotting were used to explore the exact mechanism. By establishing transformed human gastric epithelial cells via chronic low dose treatment, a gradually ING4 downregulation was observed in the later-stage of MNNG-induced cell transformation. Moreover, we demonstrated that MNNG exposure-reduced ING4 expression significantly resulted into aggravating angiogenesis through increasing the phosphorylation level of NF-κB p65 and subsequently DAN binding activity and regulating the expressions of NF-κB p65 downstream pro-angiogenic genes, MMP-2 and MMP-9. Our findings provided a significant mechanistic insight into angiogenesis of MNNG-transformed human gastric epithelial cell and supported the concept that ING4 may be a relevant therapeutic target for gastric cancer. Copyright © 2018 Elsevier Inc. All rights reserved.

The ING observatory in the 2015-2025 decade

Science.gov (United States)

Balcells, M.

2015-05-01

The Isaac Newton Group, after nearly 30 years of productive operation of the William Herschel, Isaac Newton and Jacobus Kapteyn telescopes, is reviewing its science focus. The central goal is to respond to the changes in the astronomical landscapes in UK, the Netherlands, and especially in Spain, now a mature world-player community with access to 10-m class telescopes on La Palma and Paranal. The current model, which exploits scientific and instrumentation diversity, will continue to be offered until 2017. In the meantime, an ING-led consortium is building WEAVE, a next-generation spectroscopic facility for the WHT. WEAVE is a multi-fibre system capable of deploying either 1000 single-fibre probes, 25 mini-IFUs or a single large IFU, to feed a two-arm bench spectrograph which delivers resolving powers of either 5000 or 20,000. WEAVE will exploit a new field corrector at the WHT that enlarges the prime-focus FOV diameter from the current 40 arcmin to 2 degrees. WEAVE will be used to carry out massive surveys that exploit Gaia data in topics of Milky Way astronomy and stellar evolution; surveys that carry out galaxy evolution studies linked to various multi-wavelength surveys, including the LOFAR radio telescope; and redshift surveys of distant galaxies for cosmology. Community fibres will be available. The expectation is that these surveys will use 70% of the WHT time until at least 2022. The rest of the time will be available via normal TAC allocations, for use of facility instrumentation. Plans for the INT include involving external institutions in the provision of new instrumentation and/or telescope upgrades in exchange for significant fractions of telescope time.

Making Central Banks Serve The Real Economy

Directory of Open Access Journals (Sweden)

Suleika Reiners

2013-10-01

Full Text Available The challenge is to redirect central bank money into the real economy and to the needs of society. If new money is issued to expand the productive capacity, there is no reason for inflation. Long-term financing could become available at an affordable price. Central bank money must not replace a sound tax system and the distribution of income and wealth, but complement them. The remaining task, apart from the financing of real needs, is the prevention of speculative asset price inflation. For this, central banks and regulators should install debt brakes for the financial sector. Furthermore, independent monetary policy calls for capital account management. It enables national central banks to find space for the conduct of their own policies in an interdependent global economy. Coordination between central banks and governments might increase as policies combine monetary, fiscal and regulatory facets. The future role of central banks should particularly lie in their insights regarding capital flows and leverage cycles and in their ability to create and withdraw money, depend­ing on economic conditions.

Forum-ing: Signature practice for public theological discourse

Directory of Open Access Journals (Sweden)

Edward P. Wimberly

2014-05-01

Full Text Available This article introduces a unique model for public theological conversation and discourse, which was developed by the Concerned Black Clergy of Atlanta (CBC. It was a model developed in response to the problems of poverty, homelessness, and the ‘missing and murdered children’ victimised in Atlanta, Georgia in the United States of America in the early 1980s. It was originally organised to respond to the economic, financial, spiritual, emotional, employment, housing and resource needs of the underserved poor. This unique practice is called forum-ing. The forum meets every Monday morning, except when there is a national holiday. It has operated 30 consecutive years. The forum has a series of presentations, including the opening prayer, self-introductions of each person, a report of the executive director, special presentations from selected community groups, reports, and then questions and answers. The end result is that those attending engage in a process of discourse that enables them to internalise new ideas, approaches, and activities for addressing poverty and injustice in the community. Key to forum-ing for the 21st century is that it is a form of public practical theology rooted and grounded in non-violence growing out of the civil rights movement of the 1950s and 1960s in the United States. The overall purpose of this article is to contribute to the effort of the Faculty of Theology at the University of Pretoria (South Africa to identify those variables that will assist religious leaders in South Africa to develop public conversational spaces to enhance democratic participation. This article presents one model from the African American community in Atlanta, Georgia. The hope is to lift up key variables that might assist in the practical and pastoral theological conversation taking place in South Africa at present.

Finanční analýza podniku Ing. Bronislav Vala

OpenAIRE

Valová, Anežka

2013-01-01

Aim of this work is to evaluate the financial performance of the company Ing. Bronislav Vala based on financial analysis from 2008 to 2012. The applied methods od financial analysis are selected for this evaluation. The used methods include vertical and horizontal analysis, analysis of ratios, analysis of differential indicators, pyramidal decomposition Du Pont, value and bankruptcy models and inter-company comparisons. The thesis is divided into theoretical and practical parts. The theoretic...

L’ingénierie pédagogique à base d’objets et le référencement par les compétences

Directory of Open Access Journals (Sweden)

Gilbert Paquette

2004-01-01

Full Text Available Nous situons l’ingénierie pédagogique au confluent du design pédagogique, du génie logiciel et de l’ingénierie cognitive. Puis, dans l’optique d’une ingénierie pédagogique à base d’objets, nous proposons une méthode permettant de représenter graphiquement les connaissances et les compétences, puis de les associer aux ressources d’apprentissage. Par la suite, nous montrons comment cette méthode peut contribuer à améliorer la qualité des environnements en ligne à chacune des phases de leur cycle de vie.

La démarche de l’« Ingénierie de la formation » appliquée dans le contexte de la didactique du FLE

Directory of Open Access Journals (Sweden)

Nicoleta-Loredana MOROSAN

2012-12-01

Full Text Available Le but de cette présentation est de faire le bilan de notre réflexion occasionnée par le stage «Ingénierie de la formation» organisé par le Centre régional francophone pour l’Europe centrale et orientale (CREFECO de l’Organisation Internationale de la Francophonie (OIF et déroulé à Sofia, du 18 au 22 juin 2012. Le séminaire a été cordonné par le formateur français Régis CRISTIN, docteur en sciences du langage. Les participants à ce stage, au nombre de 15, ont été des enseignants de FLE venant de différents établissements d’éducation de cinq pays de l’Europe centrale et orientale, à savoir l’Albanie, l’Arménie, la Bulgarie, la Moldavie et la Roumanie.

Dependence of the neutron-gamma log on the porosity of Malmian limestones from the central part of the Nida Trough

International Nuclear Information System (INIS)

Szczerba, A.

1974-01-01

Results of correlation-regression analysis of the relationship of the prosity Kp to the relative intensity of neutron-induced gamma radiation dIng are reviewed. The geophysical results and laboratory tests of Malmian carbonate rocks from 10 boreholes from the central part of the Nida trough have been utilized to study this relationship. The regression equation dIng=∫(Kp) and the nomogram to determine the porosity Kp on the basis of neutron-gamma log or neutron-gamma and gamma logs, when the correction for the content is to be considered, have been also presented. (author)

LoopIng: a template-based tool for predicting the structure of protein loops.

KAUST Repository

Messih, Mario Abdel

2015-08-06

Predicting the structure of protein loops is very challenging, mainly because they are not necessarily subject to strong evolutionary pressure. This implies that, unlike the rest of the protein, standard homology modeling techniques are not very effective in modeling their structure. However, loops are often involved in protein function, hence inferring their structure is important for predicting protein structure as well as function.We describe a method, LoopIng, based on the Random Forest automated learning technique, which, given a target loop, selects a structural template for it from a database of loop candidates. Compared to the most recently available methods, LoopIng is able to achieve similar accuracy for short loops (4-10 residues) and significant enhancements for long loops (11-20 residues). The quality of the predictions is robust to errors that unavoidably affect the stem regions when these are modeled. The method returns a confidence score for the predicted template loops and has the advantage of being very fast (on average: 1 min/loop).www.biocomputing.it/loopinganna.tramontano@uniroma1.itSupplementary data are available at Bioinformatics online.

Impact of pEGFP mediated ING4 gene on growth of glioma U251 ...

African Journals Online (AJOL)

Jane

2011-06-22

Jun 22, 2011 ... Full Length Research Paper. Impact of pEGFP mediated ING4 gene on growth of glioma U251 cells and its potential molecular mechanism. Yuefei Deng*, Bingxi Lei and Yiying Zhao. Department of Neurosurgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China.

Algõpetuse peajoon ja harupedagoogikad / Sirje Piht, Elve Voltein, Anne Uusen, Inge Timoštšuk

Index Scriptorium Estoniae

2012-01-01

Intervjuu Sirje Pihti ja Anne Uuseniga Tallinna Ülikooli algõpetuse osakonnast, Elve Volteiniga Tartu Ülikooli haridusteaduste instituudi õpetajate seminarist ja Inge Timoštšukiga Tallinna Ülikooli kasvatusteaduste instituudi pedagoogilise praktika keskusest

Superconducting properties of In-Ge mixture films

International Nuclear Information System (INIS)

Gerber, A.; Deutscher, G.

1987-01-01

We report on measurements of the perpendicular H/sub c//sub perpendicular/ and parallel H/sub c//sub X/ upper critical fields of superconducting In-Ge mixture films in a wide range of In concentrations. The resistivities of the samples varied from about 10 μΩX, corresponding to high In concentration, up to about 1300 μΩ cm, corresponding to an In concentration close to the percolation threshold of the system. The critical temperatures of the samples in a zero external field have also been studied. For high metal concentrations the results have been analyzed and found to fit the predictions of the dirty limit for type-II superconductors. Near the threshold, however, where the normal-state resistivity goes to infinity, the critical fields saturate to a finite value. This result is in accordance with the prediction of percolation theory in the anomalous diffusion regime. As the threshold is approached the anisotropy ratio decreases to a constant value of 1.2 from its homogeneous type-II limit 1.69

Une expérience pédagogique du débat public en école d'ingénieur. Le cas du nucléaire

Directory of Open Access Journals (Sweden)

Colmellere Cynthia

2014-01-01

Full Text Available Cette communication présente un dispositif pédagogique d'exercice de débat public autour d'un projet d'implantation d'un réacteur nucléaire. Cet exercice est mené depuis trois ans dans le cadre d'un cours de sociologie pour des ingénieurs de deuxième année à l'Ecole Centrale Paris. Il concerne un groupe d'une vingtaine d'élèves et s'inspire d'une situation réelle et actuelle : le projet d'implantation d'un réacteur nucléaire de type EPR à Penly (76. Dans cette contribution, nous présentons tout d'abord les enjeux de cette expérience pédagogique dans le contexte de notre établissement et les questions pédagogiques qu'elle pose. Dans une deuxième partie, nous détaillons les différentes séquences du cours qui servent à préparer ce débat. Dans la troisième, nous revenons sur le déroulement du débat et la phase de discussion critique entre les observateurs, les élèves et l'enseignante qui s'ensuit. Nous concluons sur les apports et les limites de cet exercice en les mettant en perspective avec les enjeux de l'enseignement des controverses scientifiques et techniques dans la formation des ingénieurs.

76 FR 54770 - Public Meeting: Notification by Capital One Financial Corporation, McLean, VA, To Acquire ING...

Science.gov (United States)

2011-09-02

... FEDERAL RESERVE SYSTEM Public Meeting: Notification by Capital One Financial Corporation, McLean, VA, To Acquire ING Bank, FSB, Wilmington, DE, and Indirectly To Acquire Shares of Sharebuilder... Reserve System. ACTION: Notice of public meeting. SUMMARY: Three public meetings will be held regarding...

A Study of the Central Auditory Function in Stutters by Masking Level Difference and Synthetic Sentence Identification Tests

Directory of Open Access Journals (Sweden)

Afsaneh Rajab

2007-06-01

Full Text Available Background and Aim: There are evidences that indicate a relationship between auditory processing disor¬ders and stuttering,¬ and any disorder in the central auditory function can be at least one of the underly¬ing causes of stuttering. Even though, using the most state of the art radiographic technologies, i.e. MRI, no definitive answer has been given in relative to this question. In this research, using Mask-ing Level Difference (MLD and Synthetic Sentence Identification (SSI tests, the central auditory func¬tion of stutters and normal group was evaluated.Materials and Methods: In this study was analytic cross-sectional, fifteen male patients with stutter-ing and 15 male normal cases with the age range from 16 to 40 years (average age 26.78 year were evalu¬ated. SSI-ICM, SSI-CCM and MLD tests were performed. The results were compared in both groups.Results: Although stutterers mean MLD was less than that of normal group, the different was not signifi¬cant between stutters and normal group in SSI test in right ear at negative MCRs. There was a signifi¬cant difference in ICM state, but in CCM state, there was no significant difference between the aver¬age score of two groups in various MCRs.Conclusion: The findings of this research is compatible with those of similar researches about the SSI test and the pattern of results, probably indicates a partial dysfunction of brainstem in some of the stutters.

Searching pristine source of two gabbric plutons outcroping in Central Sierras Pampeanas Range, Argentina

International Nuclear Information System (INIS)

Daziano, C.; Ayala, R.

2010-01-01

This work is about the study of two gabbric plutons outcrop ing throughout Central Sierras Pampeanas range (Cordoba province, Argentina). San Lorenzo hill gabbric plutons is in the Upper proterozoic age whereas Cañada del Puerto belongs to the Early proterozoic.They are stock-type igneous bodies and they are intrusive s in an Upper Precambrian crystalline basement; it is mainly composed by gneisses, migmatites, schistes, marbles, amphibolite s, tact's, serpentinites and related rocks

Sponsorship statement

Science.gov (United States)

2010-08-01

The 25th IAHR Symposium on Hydraulic Machinery and Systems benefits from the generous support of the following sponsors: National Authority for Scientific Research, RomaniaANCS logo Hidroelectrica S.A., RomaniaHidroelectrica_logo Machine Buiding Factory - UCM Reşiţa, RomaniaUCM Resita logo Hydro-Engineering S.A., RomaniaHydro Engineering logo Voith Hydro Holding GmbH, GermanyVoith_logo Andritz Hydro GmbH, AustriaAndritz_logo_large logo Alstom Hydro, FranceAlstom logo Advanced Design Technology Ltd., United Kingdomadt_logo logo

The intense neutron generator INGE-1 at the Technical University of Dresden

International Nuclear Information System (INIS)

Bittner, M.; Meisner, A.; Paffrath, E.; Schwiers, H.; Seeliger, D.

1989-01-01

The INGE-1 neutron generator developed for intergal 14 MeV neutron experiments is described. The accelerator produces steady d + ion beam in the current range of 1-10 mA with 120-240 keV energies at the target position. The beam is produced with a combined duoplasmatron focalization system on high voltage. A 30 keV beam is accelerated on final energy by a two-gap acceleration tube. The estimations conducted show that the generator maximum strength can reach up to 2x10 12 s -1 at 10 mA beam current and 220 keV energy. 4 refs

Le "projet G." : une ingénierie de formation. Conception et gestion d'un dispositif d'enseignement (le geste et l'effet)

OpenAIRE

Marty , Olivier

2012-01-01

Document de travail pour l'Axe 4 "Organisations et formation" du CRF [Avec une note additive formalisant les données empiriques]; Le projet d'ingénierie de formation décrit consiste à développer une école de gestion en ligne, d'une durée de trois années, visant un public d'une soixantaine de néo-bacheliers, avec une équipe pédagogique d'une dizaine d'enseignants employés par le Ministère. Décrire ce projet nous permet de présenter l'organisation et l'ingénierie de formation en utilisant à la ...

Kui suur palk oleks õpetaja töö vääriline? / Inge Kalle, Maia Uibo, Lauri Leesi ... [jt.

Index Scriptorium Estoniae

2011-01-01

Küsimusele vastavad Vastse-Kuuste kooli direktor Inge Kalle, Ülenurme gümnaasiumi õpetaja-metoodik Maia Uibo, Tallinna Prantsuse Lütseumi direktor Lauri Leesi, Saaremaa ühisgümnaasiumi direktor Viljar Aro ja Heimtali põhikooli direktor Eero Metsavahi

Queer(y)ing New Schooling Accountabilities through "My School": Using Butlerian Tools to Think Differently about Policy Performativity

Science.gov (United States)

Gowlett, Christina

2015-01-01

This article takes the role of provocateur to "queer(y)" the rules of intelligibility surrounding new schooling accountabilities. Butler's work is seldom used outside the arena of gender and sexualities research. A "queer(y)ing" methodology is subsequently applied in a context very different to where it is frequently…

Disposable and Usable Pasts in Central European Cities

Directory of Open Access Journals (Sweden)

Agata Lisiak

2009-12-01

Full Text Available In Central European cities memories and material histories of socialist regimes remain particularly difficult to address and incorporate into the new democratic present. After 1989, city authorities in the region have chosen to emphasize some pasts and neglect others and, thus, (rewrite their own versions of (urban history and (reshape their (urban identities. In my paper I inquire into how post-1989 Central European urbanities are shaped by and communicated through various designations including signs and symbols on city streets, monuments, and build-ings. Predictably, many material remnants of the socialist regimes have been de-stroyed or hidden from the public eye - my interest lies not only in which various designations on buildings and which monuments had to go, but also in why and how they disappeared. I discuss the most popular methods of hiding and/or effac-ing the remnants of socialism that range from subtle (surrounding of communist landmarks with tall buildings through the obvious (renaming of streets, squares, metro stations; giving old communist buildings new names and functions to the irreversible and, thus, most controversial (the razing of socialist architecture and monuments. The disappearance of the material capital of the socialist past has been accompanied by intense commemoration practices verging on memorial ob-sessions. New monuments, plaques, street names, and museums appeared almost as quickly as the old "disposable" ones were forced out from the urban landscape. The complexity of an urban identity as communicated through city streets, mo-numents, and buildings not only invites, but necessitates an interdisciplinary ap-proach and, thus, my analysis includes elements from such diverse areas of know-ledge as aesthetics, architecture, communication studies, comparative cultural studies, economics, history, and political science.

Financing hydropower projects using the mechanisms provided by the Kyoto Protocol

International Nuclear Information System (INIS)

Eugenia Anca Echizli

2004-01-01

One of the most serious and current environmental global problems is the Climate Change generated by the increasing of Green House gas (GHG) level. Romania has signed the United Nation Framework Convention on Climate Change and is the first country listed in Convention Annex I which ratified Kyoto Protocol. Romania committed itself to lower the level of GHG emissions with 8% as compared with the GHG emissions level in 1989, what is similar to the commitment of EU countries. In order to satisfy the requirements of accession to the European Union, Romania has also developed several national strategies to promote sustainable development. Hidroelectrica's Environmental Policy includes international partnership to finance the hydropower projects under Kyoto Protocol of United Nation Framework Convention on Climate Change. Hidroelectrica has submitted Joint Implementation projects to the PCF program of World Bank and ERUPT programs of Dutch Government. The paper reflects Hidroelectrica's experience in that field: the actions necessary to initiate and promote such projects, the steps recommended in developing their implementation, difficulties and barriers, results obtained, learned lessons. (author)

Quality of wooden chips produced by Claas Jaguar fitted with experimental CRA-ING rotor

Energy Technology Data Exchange (ETDEWEB)

Pari, L.; Civitarese, V.; Del Giudice, A. [Council for Research in Agriculture, Agricultural Engineering Research Unit, Rome (Italy)

2010-07-01

This paper described a newly developed chipper device for mounting on Claas Jaguar chipper harvesters for short rotation forestry harvesting. It was designed by the Agriculture Engineering Research Unit of the Agricultural Research Council in Rome, Italy. The new rotor has a lower number of blades compared to standard rotors and has a different cutting angle and drum insertion. This study evaluated the particle-size distribution of wood chips produced by standard rotors compared to those with the experimental rotor. The objective was to distinguish the particle size distribution of chips produced using the two types of chippers in order to evaluate the influence of wooden species in the chip formation process. Tests were conducted using 860 and 890 Claas Jaguar chipper harvesters, both equipped with standard and CRA-ING rotors. The experiment was conducted on poplar cultivations on biennial shift and on arboreal cultivations. Compared to traditional rotors, CRA-ING rotors provide a considerable product increase within particle sizes ranging from 12.5 to 25 mm, and an equivalent product reduction within the finest particle size classes. The study showed that the new rotor tends to concentrate dimensional increments along the longitudinal section of the chip, regardless of the species used. In order to obtain a better quality chip in terms of particle size, a second rotor was devised to engrave a cleaner cut on the biomass introduced by the feeding rollers.

Techniques de l’ingénieur, a long-awaited resource

CERN Multimedia

GS Department

2009-01-01

Since 1 August 2009, a new online resource Les techniques de l’Ingénieur has been available at CERN: and its corpus of over 4,000 articles covering 11 disciplines is now accessible from your computer. This multidisciplinary database covers many subjects ranging from mechanics to the environment. The articles are written by scientific experts recognized in their fields. Online access includes the archives since 1946; it also serves to monitor the latest trends and innovations, and new industry products. This database is therefore both a valuable resource in past and present scientific and technological information and a tool to observe future developments. Anyone can create a free account on this resource. This account is needed to configure your personal alerts and download pdf files of the documents you are interested in. More information on the Library website. Direct access to the database

SpoonEMF, une brique logicielle pour l'utilisation de l'IDM dans le cadre de la réingénierie de programmes Java5

OpenAIRE

Barais , Olivier

2006-01-01

2 ième Journée sur l'Ingénièrie Dirigée par les Modèles; Ce document présente succinctement SpoonEMF, une brique logicielle pour l'utilisation de l'IDM dans le cadre de la réingénierie d'applications écrites en Java. L'accent dans cette courte présentation est mis sur les cas d'utilisation possibles de cette brique logicielle et l'intérêt des choix techniques retenus : le framework EMF pour l'expression du méta-modèle afin de favoriser l'interopérabilité avec d'autres outils et l'intégration ...

Télécoms pour l’ingénierie du risque, Tullio Tanzi, Patrick Perrot

Directory of Open Access Journals (Sweden)

Jean-Baptiste Morin

2013-04-01

Full Text Available "Télécoms pour l’ingénierie du risque" est un ouvrage de 234 pages qui convoque la rencontre entre les Technologies de l’Information de la Communication (TIC et le risque. Les risques naturels, les risques industriels et technologiques ou encore les nouveaux risques générés par des usages déviants dans le domaine du numérique (cybercriminalité sont devenus monnaie courante. Les auteurs Tullio Tanzi (Professeur à Télécom ParisTech, département Traitement du Signal et des Images en télécommun...

CeasIng Cpap At standarD criteriA (CICADA): predicting a successful outcome.

Science.gov (United States)

Yin, Yue; Broom, Margaret; Wright, Audrey; Hovey, Donna; Abdel-Latif, Mohamed E; Shadbolt, Bruce; Todd, David A

2016-01-01

This is a retrospective analysis of a multicentre randomised controlled trial (RCT) where we concluded that CeasIng Cpap At standerD criteriA (CICADA) in premature babies (PBs) CPAP. To identify factors that may influence the number of attempts to cease CPAP, we reviewed the records of 50 PBs from the RCT who used the CICADA method. PBs were grouped according to number of attempts to cease CPAP (fast group ≤2 attempts and slow group >2 attempts to cease CPAP). There were 26 (fast group) and 24 (slow group) PBs included in the analysis. Results showed significant differences in mean GA (27.8 ± 0.3 vs 26.9 ± 0.3 [weeks ± SE], p = 0.03) and birth weight ([Bwt]; 1080 ± 48.8 vs 899 ± 45.8 [grams ± SE], p = 0.01) between groups. Significantly fewer PBs in the fast group had a patent ductus arteriosus (PDA) compared to the slow group (5/26 (19.2%) vs 13/24 (54.2 %), p = 0.02). Bwt was a significant negative predictor of CPAP duration (r = -0.497, p = 0.03) and CPAP ceasing attempts (r = -0.290, p = 0.04). PBs with a higher GA and Bwt without a PDA ceased CPAP earlier using the CICADA method. Bwt was better than GA for predicting CPAP duration and attempts to cease CPAP. Our previous studies showed that CeasIng Cpap At standarD criteriA (CICADA) significantly reduces CPAP time, oxygen requirements and caffeine use. Some PBs however using the CICADA method required >2 attempts to cease CPAP ('slow CICADA' group). PBs in the 'fast CICADA' group (CPAP) (a) have longer gestational age and higher birth weight, (b) shorter mechanical ventilation and (c) lower incidence of patent ductus arteriosus. Attempts to cease CPAP decreased by 0.5 times per 1 week increase in GA and 0.3 times per 100-g increase in birth weight for PBs <30 weeks gestation.

Spre[ing amelanotic malignant melanoma: A rare differential diagnosis with tumors of the glandula submandibularis

International Nuclear Information System (INIS)

Ehrenberg, C.; Helmberger, H.

1998-01-01

The case reported emphasizes the importance of immediate performance of imaging scans in case of the slightest suspicion that clinical symptoms might indicate malignancy of a detected lesion. Despite the superficially only marginal macroscopic findings, MR imaging as well as the CT scans revealed an [vanced, malignant process that h[ been spre[ing. Particularly the soft tissue differential diagnosis obtained with MRI yields the information required for diagnostic characterization of the space occupying tumor mass. It will however be necessary in any case to verify the diagnosis by biopsy or extirpation and cytologic examination of tissue, as the imaging methods do not always unambigiously reveal the malignant dignity of the tumor. (orig./CB) [de

Mida teed siis, kui töötaja on avaldanud soovi firmast lahkuda? / Inge Rumessen, Andres Hall, Mariliin Saar ... [jt.

Index Scriptorium Estoniae

2016-01-01

Küsimusele vastavad PR Strategies partner ja strateegiline konsultant Inge Rumessen, auto24ring juhataja Andrs Hall, vabakutseline loovjuht ja produtsent Mariliin Saar, advokaadibüroo Tark partner Hannes Küün, ettevõtte Ööloom ja Frank kaasasutaja Jan Plaan, haridus- ja teadusministeeriumi personaliosakonna juhataja Margot Saluse, Sorry as Service müügijuht ja asutaja Indrek Põldvee ja EBS-i rahvusvahelise koostöö prorektor Toomas Danneberg

Tales of Recombinant Femininity: "The Reincarnation of Golden Lotus," the "Chin P'ing Mei," and the Politics of Melodrama in Hong Kong.

Science.gov (United States)

Fore, Steve

1993-01-01

Examines the film "The Reincarnation of Golden Lotus" and the text upon which it is loosely based, the "Chin P'ing Mei," and the relationship between it and modern Chinese culture. States that the film's screenplay is much less an adaptation of the source novel than it is a female-centered reworking of a particular narrative…

Iterative Neighbour-Information Gathering for Ranking Nodes in Complex Networks

Science.gov (United States)

Xu, Shuang; Wang, Pei; Lü, Jinhu

2017-01-01

Designing node influence ranking algorithms can provide insights into network dynamics, functions and structures. Increasingly evidences reveal that node’s spreading ability largely depends on its neighbours. We introduce an iterative neighbourinformation gathering (Ing) process with three parameters, including a transformation matrix, a priori information and an iteration time. The Ing process iteratively combines priori information from neighbours via the transformation matrix, and iteratively assigns an Ing score to each node to evaluate its influence. The algorithm appropriates for any types of networks, and includes some traditional centralities as special cases, such as degree, semi-local, LeaderRank. The Ing process converges in strongly connected networks with speed relying on the first two largest eigenvalues of the transformation matrix. Interestingly, the eigenvector centrality corresponds to a limit case of the algorithm. By comparing with eight renowned centralities, simulations of susceptible-infected-removed (SIR) model on real-world networks reveal that the Ing can offer more exact rankings, even without a priori information. We also observe that an optimal iteration time is always in existence to realize best characterizing of node influence. The proposed algorithms bridge the gaps among some existing measures, and may have potential applications in infectious disease control, designing of optimal information spreading strategies.

Running injuries and associated factors in participants of ING Taipei Marathon.

Science.gov (United States)

Chang, Wei-Ling; Shih, Yi-Fen; Chen, Wen-Yin

2012-08-01

To investigate the distribution of lower extremity running injuries and their associated factors. Descriptive and exploratory study. 1004 participants of the 2005 ING Taipei International Marathon. We used a self-developed questionnaire to collect data of previous running injuries and applied multivariate logistic regression modeling to examine relationships between these injuries and associated factors. Of the 893 valid questionnaires, 396 (44.4%) reported having previous lower extremity pain related to running. Knee joint pain was the most common problem (32.5%). Hip pain was associated with the racing group, training duration, and medial arch support. Use of knee orthotics (P = 0.002) and ankle braces (P = 0.007) was related to a higher rate of knee and ankle pain. Participants of the full marathon group who practiced on a synthetic track had a higher incidence of ankle pain. A training duration of >60 min was linked to an increased rate of foot pain (P = 0.003). Our data indicated that running injuries were associated with training duration and use of orthotics. Clinicians can use this information in treating or preventing running associated injuries and pain. Copyright © 2011 Elsevier Ltd. All rights reserved.

Renewable energies for power generation in Latin America: market, technologies and perspectives; Energias renovables para generacion de electricidad en America Latina: mercado, tecnologias y perspectivas

Energy Technology Data Exchange (ETDEWEB)

De Martino Jannuzzi, Gilberto [Universidade Estadual de Campinas, UNICAMP e International Energy Initiative (Brazil); De Buen Rodriguez, Odon [Energia, Tecnologia y Educacion, S.C., ENTE, S.C. (Mexico); Gorenstein Dedecca, Joao [International Energy Initiative, IEI (Brazil); Goncalves Nogueira, Larissa [International Energy Initiative, IEI (Brazil); Maia Gomes, Rodolfo Dourado [International Energy Initiative, IEI (Brazil); Navarro, Judith [Energia, Tecnologia y Educacion, S.C., ENTE, S.C. (Mexico)

2010-07-01

many environmental obstacles exist. Bolivia, Ecuador and Peru are the South American countries that still have the greatest availability of economically viable water resources to be exploited, since those countries do not even use 7% of the available potential. Venezuela and Paraguay stand out in South America as using more than 50% of the economically available potential for hydroelectric generation in the region. Geothermal energy is an important resource in Mexico and Central America, with an installed capacity of 965 MW and 502 MW in 2008, respectively. In those two cases, this is the primary source of power generation. Argentina's high-enthalpy fields are sufficient for geothermal use to generate energy, but there is no estimate of the generation potential. Chile is another country that tries to develop its geothermal potential. In 2009, the government of Chile requested bids for 20 contracts for geothermal energy exploitation. During the geothermal bidding process, 59 offers from exploitation projects were received and 9 companies were granted licenses for the 20 areas solicited. Biomass is an especially important energy resource in Brazil, where it has already surpassed CHP. It is also relevant in Argentina and Colombia, where it is associated with the alcohol-sugar industry and a growing interest in cogeneration systems. [Spanish] America Latina posee un rico patrimonio de recursos energeticos renovables, a pesar de que, historicamente, el aprovechamiento de estos recursos en la region se haya realizado a traves de grandes centrales de energia hidroelectrica. Sin embargo, hay un inmenso potencial de utilizacion mas amplia de nuevas fuentes de energia renovables: Pequenas Centrales Hidroelectricas (PCH), eolica, solar, geotermica, de acuerdo con lo que presenta en este informe. Considerando solamente las fuentes renovables utilizadas para la generacion de electricidad en los paises estudiados, se observa que dichas fuentes participan con entre el 2.5 y el 5

Renewable energies for power generation in Latin America: market, technologies and perspectives; Energias renovables para generacion de electricidad en America Latina: mercado, tecnologias y perspectivas

Energy Technology Data Exchange (ETDEWEB)

De Martino Jannuzzi, Gilberto [Universidade Estadual de Campinas, UNICAMP e International Energy Initiative (Brazil); De Buen Rodriguez, Odon [Energia, Tecnologia y Educacion, S.C., ENTE, S.C. (Mexico); Gorenstein Dedecca, Joao [International Energy Initiative, IEI (Brazil); Goncalves Nogueira, Larissa [International Energy Initiative, IEI (Brazil); Maia Gomes, Rodolfo Dourado [International Energy Initiative, IEI (Brazil); Navarro, Judith [Energia, Tecnologia y Educacion, S.C., ENTE, S.C. (Mexico)

2010-07-01

many environmental obstacles exist. Bolivia, Ecuador and Peru are the South American countries that still have the greatest availability of economically viable water resources to be exploited, since those countries do not even use 7% of the available potential. Venezuela and Paraguay stand out in South America as using more than 50% of the economically available potential for hydroelectric generation in the region. Geothermal energy is an important resource in Mexico and Central America, with an installed capacity of 965 MW and 502 MW in 2008, respectively. In those two cases, this is the primary source of power generation. Argentina's high-enthalpy fields are sufficient for geothermal use to generate energy, but there is no estimate of the generation potential. Chile is another country that tries to develop its geothermal potential. In 2009, the government of Chile requested bids for 20 contracts for geothermal energy exploitation. During the geothermal bidding process, 59 offers from exploitation projects were received and 9 companies were granted licenses for the 20 areas solicited. Biomass is an especially important energy resource in Brazil, where it has already surpassed CHP. It is also relevant in Argentina and Colombia, where it is associated with the alcohol-sugar industry and a growing interest in cogeneration systems. [Spanish] America Latina posee un rico patrimonio de recursos energeticos renovables, a pesar de que, historicamente, el aprovechamiento de estos recursos en la region se haya realizado a traves de grandes centrales de energia hidroelectrica. Sin embargo, hay un inmenso potencial de utilizacion mas amplia de nuevas fuentes de energia renovables: Pequenas Centrales Hidroelectricas (PCH), eolica, solar, geotermica, de acuerdo con lo que presenta en este informe. Considerando solamente las fuentes renovables utilizadas para la generacion de electricidad en los paises estudiados, se observa que dichas fuentes participan con entre el 2.5 y el 5% de

Finance computationnelle et gestion des risques ingénierie financière avec applications Excel (Visual Basic) et Matlab

CERN Document Server

Racicot, François-Éric

2006-01-01

Ce manuel propose un exposé rigoureux de la gestion des risques en finance. Les aspects théoriques de la question sont abordés par des démonstrations claires et des rappels élaborés des bases mathématiques de la finance computationnelle. Le texte est émaillé de nombreux programmes écrits en langages Visual Basic (Excel), Matlab et EViews qui prépareront l'étudiant à sa carrière de spécialiste en ingénierie financière.

Mapping the social impacts of small dams: The case of Thailand's Ing River basin.

Science.gov (United States)

Fung, Zali; Pomun, Teerapong; Charles, Katrina J; Kirchherr, Julian

2018-05-24

The social impacts of large dams have been studied extensively. However, small dams' social impacts have been largely neglected by the academic community. Our paper addresses this gap. We examine the social impacts of multiple small dams in one upstream and one downstream village in Thailand's Ing River basin. Our research is based on semi-structured interviews with beneficiaries, government and NGOs. We argue that small dams' social impacts are multi-faceted and unequal. The dams were perceived to reduce fish abundance and provide flood mitigation benefits. Furthermore, the dams enabled increased access to irrigation water for upstream farmers, who re-appropriated water via the dams at the expense of those downstream. The small dams thus engendered water allocation conflicts. Many scholars, practitioners and environmentalists argue that small dams are a benign alternative to large dams. However, the results of our research mandate caution regarding this claim.

Teeninduse taseme hoidmine ja heade teenindajate leidmine on tööandjatele võtmeküsimus / Anu-Mall Naarits, Anneli Mere, Kristjan Laja, Inge Suder

Index Scriptorium Estoniae

2009-01-01

Anu-Mall Naarits Maratist, Anneli Mere Matkasport OÜ-st, Kristjan Laja Ambient Marketingist ning Inge Suder AS-ist Eesti Post vastavad küsimustele, mis puudutavad tagasisidet teenindusele, teenindajatele pakutavaid koolitusi ja motivatsioonipakette, teeninduse taset Eestis, teenindustöötajate palgataset, hea teenindaja isikuomadusi ning raskemaid ülesandeid teenindaja töös

The Implementation of Monetary Policy in an Emerging Economy: The Case of Chile

OpenAIRE

Christian A Johnson; Rodrigo Vergara

2005-01-01

Central bank authorities base implementation of monetary policy on an analysis of multiple variables known as monetary policy indicators. In a small open economy such as Chile, these indicators may include in-flation misalignments, unemployment, GDP growth, money growth, the current account balance, exchange rate volatility and international re-serves. A neural network approach is used to establish the correspond-ing weights considered by the Board of the Central Bank of Chile dur-ing the per...

Cambodian and their Doctors, a Medical Anthropology of Colonial and Post-Colonial Cambodia, Jan Ovesen & Ing-Britt Trankell

Directory of Open Access Journals (Sweden)

Didier Bertrand

2012-09-01

Full Text Available Cet ouvrage, écrit par Jan Ovesen et Ing-Britt Trankell (professeurs associés d’anthropologie à l’université d’Uppsala engagés dans l’étude de la société cambodgienne depuis 1995, offre une synthèse unique d’anthropologie historique et d’ethnographie contemporaine sur le système de soins de santé cambodgien de la colonisation française à nos jours. Les auteurs décrivent la tension dans le Cambodge moderne entre la tradition médicale occidentale introduite par les colonisateurs français et le...

In-core fuel management for Cofrentes NPP

International Nuclear Information System (INIS)

Marco, M.

1990-01-01

Hidroelectrica Espanola has established an in-house nuclear analysis capability in Hidrola's Servicio de Ingenieria y Analisis Nucleares (SIAN). This article describes SIAN, its origins, resources, codes, and its work related to the company's 100%-owned Cofrentes NPP. 1 fig., 2 tabs

Ingénierie de la maintenance De la conception à l'exploitation d'un bien

CERN Document Server

Francastel, Jean-Claude

2003-01-01

La maintenance a évolué : d’abord confinée à l’entretien des équipements “réparer“ les pannes puis élargie à leur surveillance “prévoir” les pannes elle est intégrée aujourd’hui dès la phase de conception du produit avec notamment le concept de “maintenabilité” du produit. L’ingénierie de maintenance désigne ce processus d’accompagnement d’un bien industriel durant toutes les phases de son cycle de vie de la conception au démantèlement qui permet d’optimiser l’exploitation de ce bien et son coût global life cycle cost. Cet ouvrage décrit les différentes phases du cycle de vie en exposant les techniques qui permettent d’intégrer à chaque étape les concepts de maintenance.

Kes peaks tagama seaduste täitmise? / Inge Timoštšuk, Volli Kalm, Maiki Udam ; üles kirjutanud Ülo Tikk

Index Scriptorium Estoniae

Timoštšuk, Inge, 1970-

2001-01-01

Vene koolidel käib Põhikooli- ja Gümnaasiumiseaduse § 52 teise lõike "Riigi- ja munitsipaalgümnaasiumides alustatakse üleminekut eesti õppekeelele hiljemalt 2007/08. õppeaastal" täitmine üle jõu, kuna ei jätku pädevaid õpetajaid. Teemat kommenteerivad Tartu Ülikooli prorektor Volli Kalm, Tallinna Pedagoogikaülikooli õpetajakoolituse osakonna juhataja Inge Timoštšuk ja Haridusministeeriumi kõrghariduse talituse juhataja Maiki Udam

Dr Oen Boen Ing Patriot doctor, social activist, and doctor of the poor

Directory of Open Access Journals (Sweden)

Ravando Lie

2017-05-01

Full Text Available This article examines the efforts and achievements of Oen Boen Ing, a Tionghoa doctor, to improve the quality of health of the poorer inhabitants of Surakarta. Dr Oen played an important role in five different periods: Dutch colonialism, the Japanese occupation, the Indonesian revolution, Soekarno’s regime, and Suharto’s New Order. Known for being a benevolent doctor, activist, and patriot of the revolution during his life-time, Dr Oen also gave medical assistance to the needy, which famously earned him the accolade of “doctor of the poor”. During the Indonesian revolution, Dr Oen assisted the Student Soldiers (Tentara Pelajar and afterwards was appointed the member of Supreme Advisory Council (Dewan Pertimbangan Agung/DPA by Soekarno in 1949. As a benevolent doctor and activist, Dr Oen is remembered for founding the Panti Kosala Hospital which was renamed to perpetuate his name on 30 October 1983, exactly a year after his passing. When he died, thousands of peoples gathered to pay their final respects to the doctor. He was honoured with a ceremony conducted in the Mangkunegaran Palace. Dr Oen’s name will be eternally respected, especially in Surakarta.

The plays of Lillian Hellman, Clifford Odets and William Inge on Slovene stages

Directory of Open Access Journals (Sweden)

Mateja Slunjski

2002-12-01

Full Text Available After the Second World War, Slovene theatres started to include in their repertoires more and more American authors and their plays. Their choice were varied, from serious dramas by Eugene O'Neill, Tennessee Williams and Arthur Miller, to comedies by Norman Krasna and John Van Druten dependant mostly on the availability of the texts. In the immediate postwar years the theatres liked to present playwrights with progressive ideas in their plays, such as Lillian Hellman and her "The Little Foxes", which was successfully produced at three Slovene theatres, while her "The Children's Hour" received negative reviews. In the fifties, three theatres chose two plays by Clifford Odets, "Golden Boy" and "Country Girl", mainly because of his socially critical ideas and his admiration of humanity. His plays were rather well received; however, the critics doubted his literary genius. William Inge and his plays, "Come Back, Little Sheba", "Picnic" and "Bus Stop", chosen mainly because of the warmth with which the author depicted the tragedy and the beauty of life, were produced at three Slovene theatres. The author received rather wide-ranging opinions from the critics. Some thought him to be an unoriginal depicter of dull American life, while others praised his lyricism and new dramatic techniques.

Les métiers innovants de la formation. Le champ de la formation professionnelle et l'ingénierie de formation à distance

OpenAIRE

Marty, Olivier

2013-01-01

National audience; This document is extracted from a conference for PhD students at La Sorbonne University (Paris) about innovative teaching professions. It describes and analyses the crafts of vocational education as well as public distance education engineering.; Ce document est le support d'une conférence sur les métiers innovants de la formation. Après les définitions d'usage, il décrit et analyse les métiers de la formation professionnelle continue et l'ingénierie de formation à distance...

Toxic gas emissions from the Kayseri peat deposit, central Anatolia ...

Indian Academy of Sciences (India)

gas entry is directly from the ground through the floors, walls, and especially subsurface telephone cable pipes. .... in home pose both safety and health risks. These .... regulatory monitoring, research work and compost- ing applications.

Defense Manpower Policies in Northern and Central European NATO.

Science.gov (United States)

1980-02-01

in the Netherlands generally falling into the follow- ing categories: breadwinners , those personally indispensable, those holding ecclesiastical...in The Military Balance 1977/78, pp. 104-105. Indeed there is only limited utility in comparing just peacetime strengths, since in crisis or conflict

Sedimentary environments in the south-western Barents Sea during the last deglaciation and the Holocene: a case study outside the Ingøydjupet trough

Directory of Open Access Journals (Sweden)

Mauro Pau

2016-05-01

Full Text Available A lithological and foraminiferal study of newly acquired sediment cores outside the Ingøydjupet (Ingøy Deep trough has been carried out to improve constraints on the last deglacial history in the south-western Barents Sea. Three lithofacies and three foraminiferal facies were identified. The lowermost lithological unit is a diamicton interpreted as glacial till. It contains a low-abundance, ecologically mixed foraminiferal assemblage, presumably resulting from glacial reworking. Above the diamicton, a layer of ice-rafted debris (IRD, likely associated with intensive iceberg production, marks the initial destabilization of the marine-based ice sheet. At this time, ca. 15.6–15.0 Ky B.P., opportunistic foraminiferal species Nonionellina labradorica and Stainforthia spp. reached peak abundance. During the south-western Barents Sea ice-margin retreat, presumably corresponding to the Bølling interstadial, a sequence of glaciomarine laminations was deposited conformably on the layer of IRD. Sedimentation rates were apparently high (estimated about 0.4 cm per year and the foraminiferal fauna was dominated by Elphidium spp. and Cassidulina reniforme, species common for glacier-proximal environments. A hiatus at the top of the deglacial unit is likely linked to the high bottom-current activity associated with a strengthened inflow of Atlantic water masses into the Barents Sea. The uppermost lithological unit is represented by the Holocene marine sandy mud. It contains a high-abundance, high-diversity foraminiferal fauna with common cassidulinids, Cibicides spp., Epistominella pusilla and planktic species.

Streptococcus In man m illeri causIng infection

African Journals Online (AJOL)

1983-04-30

Apr 30, 1983 ... every organ system. Bacteraemia due to Strept. mil- leri was a significant indicator of the presence of an occult abscess. Endocarditis was rare. The penicillins or ... liver, central nervous system, lungs, appendix, pleural cavity and pelvis, as well as from ... or predisposing factors and therapy. Results.

DTN and international cooperation of the Spanish Nuclear Sector in nuclear technology development processes

International Nuclear Information System (INIS)

Acero, M.

1995-01-01

The Spanish electrical utilities with interests in the Nuclear Sector-IBERDROLA, ENDESA,FUERZAS ELECTRICAS DE CATALU=A5A (FECSA), UNION ELECTRICA FENOSA S.A., COMPA=A5IA SEVILLANA DE ELECTRICIDAD S.A., AND HIDROELECTRICA DEL CANTABRICO S.A.-created on September 26, 1994 the ''Agrupacion Electrica para el Desarrollo Tecnologico Nuclear, A.I.E. (DTN)'' (Electrical Society for Nuclear technology Development A.I.E.) for the purpose of promoting and managing Nuclear Nechnology Development, and integrating and coordinating the efforts of the Nuclear Electrical Sector with industrial companies and other related institutions in spain and abroad. This mission is primarily accomplished by establinhing a common strategy for the Nuclear Electrical Sector in the different areas of responsibility of DTN, centralizing actions by implementing a clear and coherent policy, and ensuring the presence of the entire Electrical Sector in all those fora deemed to be strategic to the Nuclear Sector

Gérer l'interface entre ingénierie, didactique, pédagogie et dispositifs ouverts Interfacing open learning environments, didactics and pedagogy

Directory of Open Access Journals (Sweden)

Guy Achard-Bayle

2003-06-01

Full Text Available Nous proposons de croiser le regard du didacticien linguiste et celui du spécialiste de l'utilisation des TIC pour la formation et de l'ingénierie de formation, afin d'analyser des dispositifs expérimentaux "ouverts" que nous avons pu observer de près. Le premier est un dispositif à distance basé sur une pédagogie du projet, le second relève de l'autoformation guidée en centre de ressources. Dans les deux cas on relève le rôle pivot du centre de ressources et la disparition du groupe-classe. Quelques points importants pour une approche des dispositifs ouverts se dégagent, entre autres tutorat et suivi des apprenants, rapport au temps (temps perdu, temps retrouvé, choix des ressources supports des apprentissages (outils de référence et matériaux pédagogiques. Nous plaiderons pour une meilleure gestion de l'interface entre ingénierie, didactique, pédagogie et dispositifs ouverts par une remobilisation du didacticien autour de quelques axes se dégageant de nos observations.We acted as linguists interested in didactics and specialists in the use of ICT to analyze two language learning environments we had an opportunity to closely follow. Both can be labeled as open learning systems relying on self directed learning. We point out the importance of the self access learning centre where learners come and the disappearance of the traditional group. Several relevant elements are analyzed such as tutoring and coaching of learners, changes in the relationship to time (wasting and finding time, choosing appropriate materials (reference tools or teaching materials. We will argue in favor of a more deliberate implication of didactics so as to better approach open learning situations and self directed learning.

The hydroelectric power plant as a project of private investment; La central hidroelectrica como proyecto de inversion privada

Energy Technology Data Exchange (ETDEWEB)

Guerra, Eduardo [Industrias Metalurgicas Pescarmona S.A. (IMPSA), Mendoza (Argentina)]. E-mail: guerra@impsa.com.ar

2001-07-01

The paper describes the process to be followed for the performance, construction and operation of a hydroelectric investment from the view point of a private investor. The paper demonstrates that it is possible to finance the project through the 'project finance', where the finance has as guarantee the own assets and the fund fluxes of the investment.

Operator training for the Yacyreta binational hydroelectric power plant; Formacion de operadores para la Central Hidroelectrica de Yacireta

Energy Technology Data Exchange (ETDEWEB)

Dure, Francisco; Tachella, Heriberto [Entidad Binacional Yacyreta, Isla Yacireta (Paraguay). Central Hidroelectrica Yacyreta]. E-mail: yacyreta@internet.siscotel.com

1998-07-01

This work is oriented to the power plant operators, by exposing the criteria and methods adopted for operators selection, training and incorporation to the Yacyreta Hydroelectric Power Plant. The used criteria considered some aspects, as follows: the operation staff should be consisted of equal numbers of Argentine and Paraguayan nationalities, viewing the both systems operation; experience of the shift supervisors in operating a plant for a minimum of 10 years; the supervisors should participate training the auxiliary operators.

Material development in the SI sub 3 N sub 4 system using glass encapsulated Hip'ing

Energy Technology Data Exchange (ETDEWEB)

Corbin, N.D.; Sundberg, G.J.; Siebein, K.N.; Willkens, C.A.; Pujari, V.K.; Rossi, G.A.; Hansen, J.S.; Chang, C.L.; Hammarstrom, J.L.

1992-04-01

This report covers a two-year program to develop fully dense Si{sub 3}N{sub 4} matrix SiC whisker composites with enhanced properties over monolithic Si{sub 3}N{sub 4} materials. The primary goal was to develop a composite with a fracture toughness > 10 MPa{radical}m, capable of using high pressure glass encapsulated HIP'ing. Coating methods were developed to apply thin (<150nm) stoichiometric BN layers to SiC whiskers and also to apply a dual coating of SiC over carbon to the whiskers. Fracture toughness of the composites was determined to increase as the quantity of whiskers (or elongated grains) with their axis perpendicular to the crack plane increased. Of the interface compositions evaluated in this effort, carbon was determined to be the most effective for increasing toughness. The highest toughnesses (6.8--7.0 MPa{radical}m) were obtained with uniaxially aligned carbon coated whiskers. There was no evidence of the carbon coating compromising the oxidation resistance of the composites at 1370{degree}C.

An Anomaly in the Inglis-Teller Limits of the C VI Lyman and Balmer Series in Laser-Produced Plasmas

Science.gov (United States)

Elton, R.; Iglesias, E.; Griem, H.; Weaver, J.; Pien, G.; Mancini, R.

2002-11-01

Soft x-ray spectra from thin carbon layers heated by the OMEGA and NIKE lasers have been obtained with both spherical and planar targets, respectively, using a flat-field grazing incidence spectrograph equipped with a gated microchannel plate for temporal resolution. In both experiments, late-time (recombining) hydrogenic C VI spectra show an n-to-1 Lyman spectral series blending with the continuum at n=4, contrary to n=9 in the n-to-2 Balmer series. It appears unlikely that plasma inhomogeneities are the sole cause of this anomaly, given the difference in the experimental configurations. Other explanations for the line-to-continuum merging (other than the usual Stark-broadened Inglis-Teller effect) under consideration include non-thermal Doppler broadening, deviations from statistical sublevel population distributions, and opacity effects. Collisional-radiative and hydrodynamic modeling, including cascades, is employed to further understand this phenomenon.

Facelift for Romanian hydro

Energy Technology Data Exchange (ETDEWEB)

Anon.

2000-09-01

The Siriu-Nehoiasu and the Ciresu-Surduc-Nehoiasu hydroelectric projects in central Romania are described. At both sites, construction work began in 1983 but funding ran out in 1994 before completion; what was achieved up to that point is described. In 1999, Hidroelectrica linked up with Harza Engineering of Romania who did a detailed review and optimization study of both schemes and formulated a plan to make completion attractive for the private sector in the new market-orientated economy. In June 2000, the two companies reached an agreement to complete construction at both sites through a jointly-owned special purpose company. Construction is expected to begin in 2001 with completion in April 2004. The differences between the new optimized schemes and the originals are given. Financing is expected to be an equal split between the state and investors under a BOT structure. The scheme at Ciresu-Surduc-Nehoiasu will provide the added benefit of reducing annual flood damage.

Caregivers' perceptions of childhood fever in Ilorin, North-Central ...

African Journals Online (AJOL)

owner

2013-01-22

Jan 22, 2013 ... Social class, maternal age and religion ... ing age and gender of the child, parental religion and ethnic group(s), as ... The mean maternal age was 29.5 ± 4.46 years (Range 21 .... for tactile assessment of fever by respondents was the dorsum of ... ters amongst parent of high and low socioeconomic classes.

18 January 2011 - Ing. Vittorio Malacalza, ASG Superconductors S.p.A, Italy in the LHC superconducting magnet test hall with Deputy Department Head L. Rossi, in the LHC tunnel at Point 5 and CMS experimental area with Spokesperson G. Tonelli.

CERN Multimedia

Maximilien Brice

2011-01-01

18 January 2011 - Ing. Vittorio Malacalza, ASG Superconductors S.p.A, Italy in the LHC superconducting magnet test hall with Deputy Department Head L. Rossi, in the LHC tunnel at Point 5 and CMS experimental area with Spokesperson G. Tonelli.

Enzymatic biosensors based on ingá-cipó peroxidase immobilised on sepiolite for TBHQ quantification.

Science.gov (United States)

Regina de Oliveira, Tássia; Grawe, Gregory Ferreira; Moccelini, Sally Katiuce; Terezo, Ailton J; Castilho, Marilza

2014-05-07

Sepiolite clay mineral was used as a support for the immobilisation of the peroxidase enzyme from ingá-cipó (Inga edulis Mart.) and was used with graphite powder, multi-walled carbon nanotubes (CNTs), mineral oil, and nafion 0.5% (v/v) in the development of a new biosensor for the determination of the antioxidant tert-butylhydroquinone (TBHQ) by square-wave voltammetry (SWV). For the optimisation and application of the biosensor, several parameters were investigated to determine the optimum experimental conditions using SWV. The best performance was obtained using a 0.1 mol L(-1) phosphate buffer solution (pH 7.0), 4.0 × 10(-4) mol L(-1) hydrogen peroxide, a frequency of 50 Hz, a pulse amplitude of 60 mV, and a scan increment of 6 mV. The biosensor showed good repeatability and reproducibility and remained stable for a period of 20 weeks. The analytical curve revealed a linear response range of 1.65 to 9.82 mg L(-1) (r = 0.994) with detection and quantification limits of 0.41 and 1.25 mg L(-1). A recovery study of TBHQ in salad dressing samples yielded values from 99.6-104.8%. The proposed biosensor was successfully used for the determination of TBHQ in commercial salad dressing samples, giving a relative error of 5.4% in relation to the comparative method (chromatographic).

Le français, clé de l’avenir professionnel de l’étudiant : exemple de la formation des ingénieurs en télécommunications

Directory of Open Access Journals (Sweden)

Mª Ángeles Lence

2014-12-01

Full Text Available Cet article veut attirer l’attention sur l’importance de la langue française dans la formation des étudiants universitaires, non seulement au niveau académique pour qu’ils puissent poursuivre leurs études dans un pays francophone, mais aussi au niveau professionnel pour leur future immersion sur le marché de l’emploi. Dans le contexte de la globalisation qui impose la maîtrise de l’anglais comme un requis inexcusable dans les offres d’emploi, la connaissance d’une deuxième langue étrangère accorde une valeur de plus au curriculum des diplômés espagnols, en les mettant en conditions égales avec leurs homologues européens, en augmentant leurs possibilités de travail au niveau international, en les rendant enfin aussi compétitifs que les diplômés d’autres universités où le bagage de deux langues étrangères conditionne l’obtention du diplôme d’ingénieur. Comme exemple, nous exposons comment les étudiants peuvent apprendre le français dans les études actuelles de Grado en Ingénierie Technique de Télécommunications de l’Universitat Politècnica de València (UPV, en comparant en même temps avec l’apprentissage des langues dans une École homologue en France.

Approches par points de vue pour l’ingénierie des Systèmes d’information

Directory of Open Access Journals (Sweden)

Brahim Lahna

2009-07-01

Full Text Available Les concepts de point de vue, de rôle, de perspective et de vue ont été largement étudiés et utilisés dans de nombreux travaux, dans divers domaines de l’informatique. On retrouve ces notions dans les Systèmes de Représentation de Connaissances par Objets, les Bases de Données Orientées Objets, les Méthodes de Conception, la Programmation Orientée Objets, etc. Chaque domaine lui donne sa propre définition et l’utilise dans son propre contexte. La notion de vue se développe indépendamment dans ces différentes disciplines. Bien que les propositions différent, elles sont confrontées aux mêmes problèmes : établir des relations entre vues et garantir la cohérence des vues entre elles ou vis-à-vis d'un modèle de référence. Nous présentons dans cet article des travaux relatifs aux notions de vues et points de vue dans différentes disciplines informatiques en insistant sur une proposition originale pour une nouvelle ingénierie des systèmes d’information orientée perspectives et composants multivues réutilisables.

(La2O3) glass–ceramic composites

Indian Academy of Sciences (India)

2017-07-26

Jul 26, 2017 ... School of Materials Science and Engineering, Central South University, Changsha 410083, PR ... ing strength, fracture toughness, glass transition temperature ... which subsequently is crystallized into a compound with a.

Large teleseismic P-wave residuals observed at the Alban Hills volcano, Central Italy

Directory of Open Access Journals (Sweden)

H. Mahadeva Iyer

1994-06-01

Full Text Available We collected teleseismic waveforms from a digital microseismic network deployed by the Istituto Nazionale di Geofisica (ING in collaboration with the U.S. Geological Survey (USGS, on the Alban Hills Quaternary volcano during the 1989-1990 seismic swann. About 50 events were recorded by the network, 30 of them by at least 4 stations. We analysed the data in order to image crustal heterogeneities beneath the volcano. The results show large delay time residuals up to - 1 second for stations located on the volcano with respect to station CP9 of the National Seismic Network located about 20 km to the east, on the Apennines. This suggests that the whole area overlies a broad low-velocity region. Although the ray coverage is not very dense, we model the gross seismic structure beneath the volcano by inverting the teleseismic relative residuals with the ACH technique. The main features detected by tbc inversion are a low-velocity zone beneath the southwestern fiank of tbc volcano, and a high-velocity region beneath the center. The depth extension of these anomalous zones ranges between 5 and 16 km. The correspondence between the low-velocity region and the most recent activity of the volcano (- 0.027 Ma leads us to infer the presence of a still hot magmatic body in the crust beneath the southwestern side of the volcano, whereas the central part overlies the older and colder high-velocity volcanic roots related to the previous central activity (0.7 to 0.3 Ma.

Flux analysis of central metabolic pathways in Geobactermetallireducens during reduction of solubleFe(III)-NTA

Energy Technology Data Exchange (ETDEWEB)

Tang, Yinjie J.; Chakraborty, Romy; Garcia-Martin, Hector; Chu,Jeannie; Hazen, Terry C.; Keasling, Jay D.

2007-01-01

We analyzed the carbon fluxes in the central metabolism ofGeobacter metallireducens strain GS-15 using 13C isotopomer modeling.Acetate labeled in the 1st or 2nd position was the sole carbon source,and Fe-NTA was the sole terminal electron acceptor. The measured labeledacetate uptake rate was 21 mmol/gdw/h in the exponential growth phase.The resulting isotope labeling pattern of amino acids allowed an accuratedetermination of the in vivo global metabolic reaction rates (fluxes)through the central metabolic pathways using a computational isotopomermodel. The tracer experiments showed that G. metallireducens containedcomplete biosynthesis pathways for essential metabolism, and this strainmight also have an unusual isoleucine biosynthesis route (usingacetyl-CoA and pyruvate as the precursors). The model indicated that over90 percent of the acetate was completely oxidized to CO2 via a completetricarboxylic acid (TCA) cycle while reducing iron. Pyruvate carboxylaseand phosphoenolpyruvate carboxykinase were present under theseconditions, but enzymes in the glyoxylate shunt and malic enzyme wereabsent. Gluconeogenesis and the pentose phosphate pathway were mainlyemployed for biosynthesis and accounted for less than 3 percent of totalcarbon consumption. The model also indicated surprisingly highreversibility in the reaction between oxoglutarate and succinate. Thisstep operates close to the thermodynamic equilibrium possibly becausesuccinate is synthesized via a transferase reaction, and the conversionof oxoglutarate to succinate is a rate limiting step for carbonmetabolism. These findings enable a better understanding of therelationship between genome annotation and extant metabolic pathways inG. metallireducens.

Cross-species amplification of microsatellites in genera ...

Indian Academy of Sciences (India)

species in Chinese freshwater polyculture system. Accord- ing to several recent ... cephala transcriptome database were chosen to test their utility for ..... 2012BAD26B00) and Fundamental Research Funds for the Central. Universities (no.

The exhibition"La France au CERN" was inaugurated by Danièle Hulin, Directrice adjointe Secteur Physique, Chimie, Sciences pour l'Ingénieur (PCSI), Ministère délégué à l'Enseignement supérieur et à la recherche.

CERN Document Server

Patrice Loïez

2005-01-01

The exhibition"La France au CERN" was inaugurated by Danièle Hulin, Directrice adjointe Secteur Physique, Chimie, Sciences pour l'Ingénieur (PCSI), Ministère délégué à l'Enseignement supérieur et à la recherche.

Ocorrência e aspectos ecológicos de metazoários parasitos de peixes do Lago do Parque do Ingá, Maringá, Estado do Paraná = Occurrence and ecological aspects of the metazoan fish parasites from Ingá lake, Maringá, Paraná State

Directory of Open Access Journals (Sweden)

Marion Haruko Machado

2007-07-01

Full Text Available Nenhum estudo de peixes e parasitos foi realizado, até o momento, no Lago do Parque do Ingá que sofre influências antrópicas desde seu represamento, em 1970. Este trabalho analisou alguns aspectos ecológicos dos parasitos metazoários dos peixes deste lago. Dos peixes analisados, (69,5% estavam parasitados por pelo menos uma espécie de parasito. Foram encontrados 1.372 parasitos pertencentes à Nematoda (larvas e Platyhelminthes (Monogenea e Cestoda, sendo estes os mais prevalentes e numerosos. O encontro de larvas decestóides em Tilapia rendalli e Oreochromis niloticus confirma a importância destas espécies como participantes de níveis tróficos intermediários. A maior abundância de T. rendalli e O. niloticus,no local, pode ser um fator determinante no recrutamento de parasitos. O parasito aproveita-se das espécies de hospedeiros mais abundantes para garantir o desenvolvimento de seu ciclo de vida e também por serem os mais disponíveis à predação pelas aves piscívorasali presentes, o que torna o local de grande importância para a sustentação do ciclo de vida desses parasitos. A baixa diversidade de endoparasitos coletados pode ser justificada pela presença de metais pesados – Cu e Pb – no sedimento, o que deve estar interferindo nodesenvolvimento dos invertebrados, possíveis hospedeiros intermediários.Ingá lake was dammed in 1970 and, since then, no study on fish and parasites had been done, but it has suffered anthropic influences. This study analyzed some ecological aspects of the metazoan parasites form this lake. From analyzed fish, 69.5% had at least one species of parasite. Among them, 1.372 parasites were found, prevailing Nematoda (larvae and Platyhelminthes (Monogenea and Cestoda. The discovery of cestode larvae in Tilapia rendalli and Oreochromis nitolicus confirms the importance of these species as participants of intermediate trophic levels. The great number of Tilapia rendalli and Oreochromis nitolicus

RESPUESTA DE PECES NATIVOS A FLUCTUACIONES DE CAUDAL PRODUCIDAS POR LA OPERACION DE CENTRALES HIDROELECTRICAS EN EL RIO BIO-BIO

OpenAIRE

GARCIA LANCASTER, ALEX DAN RODRIGO

2011-01-01

Los sistemas fluviales son ecosistemas de alta diversidad ambiental, cuyos procesos naturales operan mientras se mantengan las condiciones de heterogeneidad espacio–temporal. La biota acuática de estos ecosistemas responde a dicha diversidad presentando patrones de distribución que varían a escala espacial y temporal, asociadas a variables como la disponibilidad de hábitat, la oferta de alimento y el gasto energético asociado a mantenerse en un hábitat. Estas variables pueden ser alteradas...

Command in Air War. Centralized Versus Decentralized Control of Combat Airpower

Science.gov (United States)

2007-06-01

fears that Americans were the “Great Satan ” that its enemies claimed. Groups such as Ansar al-Islam incorporated these pictures into their recruit- ing...his steps. —Proverbs 16:9 —New American Standard Bible Air Force aircraft were not involved in the battle in Mogadishu, Somalia...Command and Control Research Pro- gram, Nov. 2002. http://www.dodccrp.org/publications/ pdf / Smith_EBO.PDF. Snook, Scott A. Friendly Fire: The Accidental

The Performance of Public Organization: Still Unclear

Directory of Open Access Journals (Sweden)

Bacanu B.

2014-12-01

Full Text Available Nowadays, the present discussions about the organisation’s performance have revealed the fact that the concept is unclear. The use of the concept is more difficult in public organisations. The paper presents the case of Romanian SOE Hidroelectrica and the case of public universities, to pinpoint the fact that ambiguous objectives are the cause of a dilemmatic management. The general opinion is that the results of the public organisations management reflect a poor performance of the latter.

Joint Force Quarterly. Number 15, Spring 1997

Science.gov (United States)

1997-06-01

time is key to the theory of control— cybernetics—and the etymology of control, a term which comes from the Latin contrarotulare, mean- ing to mark...revolution that resulted in the brain and central nervous system. Chemistry domi- nated life processes for four billion years until primitive

Within-plate Cenozoic Volcanism and Mantle Sources Within The Western-central Mediterranean Area

Science.gov (United States)

Beccaluva, L.; Bianchini, G.; Bonadiman, C.; Coltorti, M.; Siena, F.

An integrated study of anorogenic basic magmas and entrained mantle xenoliths rep- resents a promising approach for a comprehension of the magmatogenic events occur- ring within the lithospheric mantle in the western-central Mediterranean area. In this contribution we review the geochemical characteristics of mafic lavas and associated peridotite xenoliths from three anorogenic volcanic districts: Pliocene-Quaternary vol- canism of Sardinia; Pliocene-Quaternary volcanism of the Iblean area (eastern Sicily); Paleocene-Oligocene Veneto Volcanic Province. Investigations have been focused on 1) petrological features of parental magmas, which may contribute to infer the com- positional characteristics of mantle sources and to constrain the modes of partial melt- ing; 2) modelling the depletion events and metasomatic enrichments in mantle xeno- liths of the three volcanic districts, as well as the nature of their causative agents. Petrological features and Sr-Nd-Pb isotopic data, both of lava and xenoliths, indicate that DM+HIMU components distinguish the lithospheric mantle sections of Iblean and Veneto Volcanic Provinces. On the other hand, lavas and xenoliths from Sardinia display a significant different isotopic signature characterised by DM+EM1. Similar geochemical fingerprints, i.e. the significant presence of EM components are gener- ally recorded by mafic lavas and mantle xenoliths from the European Plate, whereas they are not observed in the stable African lithospheric domain.

From Dungans to Xinyimin: China, Chinese Migration and the Changing Sociopolitical Fabric of Central Asian Republics

Directory of Open Access Journals (Sweden)

Emile Kok-Kheng Yeoh

2015-08-01

Full Text Available This paper looks at the issue of ethnic identity of the Dungans – descendants of early Chinese migrants in Central Asia – and its change and preservation in the context of the fragile social fabric of the Central Asian states that were born from the shadow of the now-defunct Soviet Union, the arduous processes of nation-building plagued by often violent, competing emergent nationalisms as well as political and economic turbulence, and the impact brought by the emergence of the xinyimin (Chinese new migrants. These Chinese-speaking Dungans staying in compact communities mostly in Kazakhstan, Kyrgyzstan and Uzbekistan are descendants of political and war refugees from China’s provinces of Shaanxi and Gansu who moved across the border into the territory of Czarist Russia in the later part of the nineteenth century after the crushing of the Northwest Uprising by the Imperial Ch’ing (the Manchu dynasty army which bordered on genocide and ethnic cleansing. This paper analyses how a new ethnic identity has since emerged due partly to the geographical isolation imposed by the formidable natural barrier of the Tianshan (“Heavenly Mountains” However, their Chinese language in the form of a mixture of the Shaanxi and Gansu regionalects, remarkably written today not in Chinese characters but in the Cyrillic alphabet, and Chinese traditions of the Shaanxi and Gansu varieties have been fiercely preserved through the generations until today, including nineteenth-century vocabulary and traditions which are no longer found in modern China, due both to the cohesiveness of communal life and an aversion to marriage outside the community. After analysing the community’s dilemmas of identity preservation and identity creation, this paper then proceeds to look at the impact of the disintegration of the Soviet Union in 1991 resulting in the birth of the post-Soviet independent Central Asian republics, and the influx of the xinyimin from China since the

The PCNA-associated factor KIAA0101/p15PAF binds the potential tumor suppressor product p33ING1b

International Nuclear Information System (INIS)

Simpson, Fiona; Lammerts van Bueren, Kelly; Butterfield, Natalie; Bennetts, Jennifer S.; Bowles, Josephine; Adolphe, Christelle; Simms, Lisa A.; Young, Joanne; Walsh, Michael D.; Leggett, Barbara; Fowles, Lindsay F.; Wicking, Carol

2006-01-01

The KIAA0101/p15 PAF /OEATC-1 protein was initially isolated in a yeast two-hybrid screen for proliferating cell nuclear antigen (PCNA) binding partners, and was shown to bind PCNA competitively with the cell cycle regulator p21 WAF . PCNA is involved in DNA replication and damage repair. Using polyclonal antisera raised against a p15 PAF fusion protein, we have shown that in a range of mammalian tumor and non-tumor cell lines the endogenous p15 PAF protein localises to the nucleus and the mitochondria. Under normal conditions no co-localisation with PCNA could be detected, however following exposure to UV it was possible to co-immunoprecipitate p15 PAF and PCNA from a number of cell lines, suggesting a UV-enhanced association of the two proteins. Overexpression of p15 PAF in mammalian cells was also found to protect cells from UV-induced cell death. Based on similarities between the behaviour of p15 PAF and the potential tumor suppressor product p33ING1b, we have further shown that these two proteins interact in the same complex in cell cultures. This suggests that p15 PAF forms part of a larger protein complex potentially involved in the regulation of DNA repair, apoptosis and cell cycle progression

Mitochondrial DNA sequence variation in the Anatolian Peninsula ...

Indian Academy of Sciences (India)

Unknown

necting the Middle East, Europe and Central Asia, and, thus, has been subject to major population movements. The ... from different parts of Anatolia by direct sequencing. Analysis of the two ... the country, samples were obtained from individuals com- ing from ..... Arlequin: a software environment for the analysis of popula-.

Centralized vs. de-centralized multinationals and taxes

OpenAIRE

Nielsen, Søren Bo; Raimondos-Møller, Pascalis; Schjelderup, Guttorm

2005-01-01

The paper examines how country tax differences affect a multinational enterprise's choice to centralize or de-centralize its decision structure. Within a simple model that emphasizes the multiple conflicting roles of transfer prices in MNEs – here, as a strategic pre-commitment device and a tax manipulation instrument –, we show that (de-)centralized decisions are more profitable when tax differentials are (small) large. Keywords: Centralized vs. de-centralized decisions, taxes, MNEs. ...

Refurbishment of small hydropower plants in Romania; Sanierung von Kleinwasserkraftwerken in Rumaenien

Energy Technology Data Exchange (ETDEWEB)

Gmeinbauer, Joerg [Wien Energie GmbH, Wien (Austria)

2010-07-01

In 2008 Wien Energie subsidiary Wienstrom GmbH participated in three public auctions of Hidroelectrica S.A. for the sale of old small hydro power plants in Romania. Together with strategic partners Wienstrom could successfully compete against local and international competition and acquired 31 small hydro power plants with a total installed capacity of around 20 MW. The plants were integrated into the newly established Vienna Energy Forta Naturala Srl. and are being completely refurbished at the moment. Wien Energie consequently is already the third largest operator of small hydro power plants in Romania. (orig.)

JUST 28 No. 1 April 2008

African Journals Online (AJOL)

Administrator

2008-04-01

Apr 1, 2008 ... Over centralized administrative set ups of the. Survey Department causing undue delays in checking survey works from the regions. 3. The fear of most licensed surveyors to submit their survey works for scrutiny thereby resort- ing to back dating some survey works. 4. Intransigence on the parts of land ...

Aspergillus species as mycotoxin producers in agricultural products in central Europe

Directory of Open Access Journals (Sweden)

Kočube Šandor

2013-01-01

Full Text Available Aspergillus species are able to produce a range of mycotoxins, includ­ing e.g. aflatoxins, ochratoxins, fumonisins and patulin. Aflatoxins are mainly produced by members of Aspergillus section Flavi, and they contaminate various agricultural products in several parts of the world. Several recent reports have indicated that aflatoxin-producing fungi and consequently aflatoxin contamination occur in agricultural commodities in a number of European countries which have not been faced with this problem before. Indeed, recent surveys have clarified that concentrations of aflatoxins in maize products and milk has been exceeding the EU limit in several regions of Central Europe including Serbia, Slovenia, Croatia, Northern Italy and Romania. However, aflatoxin contamination and aflatoxin-producing Aspergillus species have not been identified yet in maize in Hungary. We examined the presence of potential aflatoxin-producing Aspergilli in maize samples collected in southern parts of Hungary. Several A. flavus isolates were identified, and pre­liminary results indicated that some of the isolates were able to produce aflatoxins. Con­tamination of other agricultural products with aflatoxins can also pose problems in Central Europe due to global warming. Ochratoxin contamination of grapes and grape-derived products is usually caused by black Aspergilli, especially by A. carbonarius and A. niger, although these species have been rare in Central European vineyards due to climatic fac­tors. Ochratoxin contamination of other agricultural products including spices and cereals was also observed in the region. Besides, ochratoxin producing Aspergilli are frequently isolated from imported products including coffee beans, dried fruits and spices, and ochra­toxin contamination of these samples was also observed. Fumonisins are produced mainly by Fusarium species, and by the recently identified producers Aspergillus niger and A. awamori. We examined fumonisin

Project of the new measurement system for energy invoicing - Itaipu Hydroelectric Central; Proyecto del nuevo sistema de medicion de energia para facturacion de la Central Hidroelectrica de Itaipu

Energy Technology Data Exchange (ETDEWEB)

Montania E, Julio Cesar [Usina Hidroelectrica de Itaipu Binacional, Assuncion (Paraguay)

2001-07-01

Itaipu Binacional has taken a decision of executing a technological updating for the energy measurement system through the substitution of the current system by other one equipped with digital devices. The main reasons for that were the following: a) The equipment in operation were of an outdated generation b) The accuracy class of the existing equipment was of 0.5%, but the tendency for invoicing measurements was to install meters with accuracy class of 0.2% in the enterprises c) The requirements of ONS/MAE, in Brazil, which establishes the minimum requisites to be attended by invoicing measurement systems.

Banco Central de Costa Rica

Directory of Open Access Journals (Sweden)

Sauter, Franz

1963-06-01

Full Text Available This new building is intended to house the various services of the Central Bank of Costa Rica. It has a prestressed concrete structure, and consists of a basement parking space for 105 vehicles, and nine storeys, providing altogether a floor surface of 12,000 ms2. The building rests on a ground area of 40 by 60 ms, and the main structure occupies 22 by 45 ms. This Bank is located in a district of narrow streets, but its main side overlooks a green open space, which will improve its visibility and appearance. The building structure is made up of a framework of prestressed beams and columns. The beams have been concreted at the site, and the joists, which are also prestressed, are factory made. This framework, at each floor level, constitutes the basis of a continuous slab, which renders the total structure exceedingly stiff. The main continuous girders span 11.22 ms spaces, and vary in cross section. The prestressing reinforcements consist of 6 Loeba type cables. This is an original design by Dr. Leonhardt, in which the cables are placed on three horizontal layers, of parabolic outline. Each cable is made up of 12 x 5.4 mm wires, with a breaking stress of 180 kg/mm2 The tensioning stress was 108 kg/mm2, and the total prestress load is 29,700 kgs. The cables run in corrugated metal tubes, and these were kept in precise position with the aid of distance pieces.El nuevo edificio, destinado a agrupar los servicios del Banco Central de Costa Rica, está constituido por una estructura de hormigón pretensado. El inmueble dispone de un sótano, estacionamiento propio para 105 vehículos y nueve plantas, con una superficie total de 12.000 metros cuadrados. Se asienta sobre una base de 40x60 m, donde se levanta un núcleo central de 22x45 metros. Está situado en un barrio de calles estrechas, pero tiene su fachada, principal frente a una zona verde que le proporcionará mayor categoría y visibilidad. La estructura se compone de una retícula de vigas

Synthesis of Er and Er : Yb doped sol–gel derived silica glass and ...

Indian Academy of Sciences (India)

Unknown

Materials Science Centre, †Central Research Facility, Optical Fibre Unit, Indian Institute of Technology,. Kharagpur 721 302, India. MS received 1 March 2004; revised 4 July 2004. Abstract. Er3+ and Er3+ : Yb3+ doped optical quality, crack and bubble free glasses for possible use in mak- ing laser material have been ...

R-ES-ONANCE--IJa-nu-arY-19-9-6

Indian Academy of Sciences (India)

ferred to as the 'central dogma' of molecular biology. Barring a few ... ing DNA into RNA is referred to as transcrip- tion, and is mediated by a .... made up of quarks (which are sub constituents of protons, neutrons ... protons and neutrons held together by nuclear forces, and negatively charged electrons which are bound ...

The generation of resonant turbulence for a premixed burner

NARCIS (Netherlands)

Verbeek, Antonie Alex; Pos, R.C.; Stoffels, Genie G.M.; Geurts, Bernardus J.; van der Meer, Th.H.

Is it possible to optimize the turbulent combustion of a low swirl burner by using resonance in turbu- lence? To that end an active grid is constructed that consists of two perforated disks of which one is rotat- ing, creating a system of pulsating jets, which in the end can be used as a central

Interaction between operation and maintenance in the Itaipu Hydroelectric Power Plant, Brazil; Interacciones entre operacion y mantenimiento en la Central Hidroelectrica Itaipu

Energy Technology Data Exchange (ETDEWEB)

Vergara Baez, Carlos A. [Itaipu Binacional, Foz do Iguacu, PR (Brazil)]. E-mail: vergara@itaipu.gov.br

1998-07-01

This paper demonstrates the importance of the human resources good relationship, cooperation, understanding and training, for obtaining optimized results from the various interactions exiting among the operation and maintenance areas.

Material development in the SI{sub 3}N{sub 4} system using glass encapsulated Hip`ing. Final report, Phase 2: DOE/ORNL Ceramic Technology Project

Energy Technology Data Exchange (ETDEWEB)

Corbin, N.D.; Sundberg, G.J.; Siebein, K.N.; Willkens, C.A.; Pujari, V.K.; Rossi, G.A.; Hansen, J.S.; Chang, C.L.; Hammarstrom, J.L.

1992-04-01

This report covers a two-year program to develop fully dense Si{sub 3}N{sub 4} matrix SiC whisker composites with enhanced properties over monolithic Si{sub 3}N{sub 4} materials. The primary goal was to develop a composite with a fracture toughness > 10 MPa{radical}m, capable of using high pressure glass encapsulated HIP`ing. Coating methods were developed to apply thin (<150nm) stoichiometric BN layers to SiC whiskers and also to apply a dual coating of SiC over carbon to the whiskers. Fracture toughness of the composites was determined to increase as the quantity of whiskers (or elongated grains) with their axis perpendicular to the crack plane increased. Of the interface compositions evaluated in this effort, carbon was determined to be the most effective for increasing toughness. The highest toughnesses (6.8--7.0 MPa{radical}m) were obtained with uniaxially aligned carbon coated whiskers. There was no evidence of the carbon coating compromising the oxidation resistance of the composites at 1370{degree}C.

Pharmacological Studies of p, N-(3, 4-Methylenedioxy phenyl Benzoic Acid (RRL-1364 - Part-I

Directory of Open Access Journals (Sweden)

Dahanukar Sharadini

1978-01-01

Full Text Available Detailed pharmacological investigations of p-N-(3, 4-methylene dioxy phenyl benzoic acid revealed marked hypotensive action which was dose dependent and most marked in cats; it was absent in rats. Atropine could block this hypotensive action, thus suggest-ing cholinomimetic mechanism. Further studies indicated that the hypotension produced was central and possibly medullary in origin.

Central sleep apnea

Science.gov (United States)

Sleep apnea - central; Obesity - central sleep apnea; Cheyne-Stokes - central sleep apnea; Heart failure - central sleep apnea ... Central sleep apnea results when the brain temporarily stops sending signals to the muscles that control breathing. The condition ...

Disseminated sulphides in basalts from the northern central Indian ridge: Implications on late-stage hydrothermal activity

Digital Repository Service at National Institute of Oceanography (India)

Banerjee, R.; Ray, D.

interplay between oceanic crust fractur- ing due to tectonically active megamullions and subsequent hydrothermal alteration, accounting for the formation of dis- seminated sulphides at the NCIR. In a novel attempt, this study examines the mineralogy... of samples. Instead, the dark greyish coloured altered basalts, frequently fractured and often with a greenish tint, dominate the assemblage. Specks of sulphides are un- evenly distributed in these altered basalts as disseminated grains or fine stringers...

A new tree-ring-based summer temperature reconstruction over the last three centuries for east-central Europe

Czech Academy of Sciences Publication Activity Database

Treml, V.; Ponočná, T.; King, G. M.; Büntgen, Ulf

2015-01-01

Roč. 35, č. 10 (2015), s. 3160-3171 ISSN 0899-8418 R&D Projects: GA MŠk(CZ) EE2.3.20.0248 Institutional support: RVO:67179843 Keywords : high-resolution paleoclimatology * climate * growth * standardization * records * millennium * mountains * responses * density * signal * tree rings * climate reconstruction * dendroclimatology * documentary evidence * Little Ice Age * warm ing * Norway spruce * proxy archives * Sudetes Subject RIV: DG - Athmosphere Sciences, Meteorology Impact factor: 3.609, year: 2015

Designing New Money

DEFF Research Database (Denmark)

Bjerg, Ole

The prospect of central banks issuing digital currency (CBDC) immediately raises the question of how this new form of money should co-exist and interact with exist-ing forms of money. This paper evaluates three different scenarios for the imple-mentation of CBDC in terms of their monetary policy...... simultaneously only pursue two out of the following three policy objectives: Free convertibility between CBDC and bank money, parity between CBDC and bank money, and central bank monetary sovereignty, which is the use of monetary policy for anything else than support for commercial bank credit creation...

Re-introduction of globally threatened Arabian Gazelles Gazella Arabica (Pallas, 1766 (Mammalia: Bovidae in fenced protected area in central Saudi Arabia

Directory of Open Access Journals (Sweden)

M.Z. Islam

2014-07-01

Full Text Available The Arabian Gazelle is a globally threatened antelope (Vulnerable in Saudi Arabia. Small relict populations remain in limited areas, while historically Arabian Gazelles occurred in Mahazat as-Sayd protected area in central Saudi Arabia but were exterminated by anthropogenic and other pressures, including habitat loss and hunting. Important habitat has been lost to agricultural developments, fencing of pasture for livestock and the construction of human settlements and roads. The reintroduction of Arabian Gazelles was undertaken in Mahazat during 2011-2014 to bring back this locally extinct species study its ecology and biology in a fenced protected area. We released a total of 49 (12 males, 37 females animals. A year after release animals started breeding and six calves have been recorded so far with more to come. The gazelles prefer to use more rocky areas where shrubs and acacia trees occur in the reserve, and do not move long distances except for one individual that moved more than 50km. Mahazat is fenced, which prevents local people from entering the reserve to poach or otherwise disturb animals. Management lessons include the need for continued monitor-ing of reintroduced populations. Interactions between Arabian and Sand Gazelles (Gazella subgutturosa marica and Arabian Oryx (Oryx leucoryx were also studied.

Orden monetario y bancos centrales Monetary order and Central Banks

Directory of Open Access Journals (Sweden)

Aglietta Michel

1996-06-01

Full Text Available Con el enfoque evolucionista e institucionalista de la economía de las convenciones francesa, este trabajo analiza el surgimiento histórico de la banca central y la creación institucional del 'arte de la banca central'. El artículo estudia los modelos formales del orden monetario, la banca libre y la banca central, y analiza los eventos históricos que llevaron a que el Banco de Inglaterra inventara el arte de manejar los bancos centrales en conjunción con el aprendizaje colectivo e institucional que lo hizo posible. Aglietta muestra que la banca central no es una creación del Estado sino una creación institucional endógena al sistema de mercado.With the evolutionist and institutionalist focus of the economics of the French conventions, this paper analyzes the historical rise of the central bank and the institutional creation of the 'art of the central bank'. The article studies formal models of the monetary order, free banking and the central bank, and analyzes the historie events that led to the Bank of England inventing the art of managing the central banks, in conjunction with the collective and institutional learning that made it possible. Aglietta shows that the central bank is not a creation of the State, but rather aninstitutional creation endogenous to the market system.

The Regional Centrality of Vietnam’s Central Highlands

DEFF Research Database (Denmark)

Salemink, Oscar

2018-01-01

strategic value turned it into a battleground among various Vietnamese parties, France, and the United States. It was here that the outcome of the Indochina wars was determined, but at a terrible price for the local population. After the adoption of economic reforms in reunified Vietnam the Central......Vietnam’s Central Highlands—or Tây Nguyên—area is usually described as remote, backward, and primitive, but this region has played a central role in the history of the surrounding states and the wider East and Southeast Asia region. Far from isolated, the Central Highlands engaged in trade...... various rivalrous polities now known as Vietnam, Champa, Cambodia, Laos, and Thailand, the area occupied a strategic position in the wider mainland Southeast Asia region. With the emergence of a unified, neo-Confucianist Vietnamese state the region lost its centrality until the late colonial era, when its...

MUSE-INGS ON AM1354-250: COLLISIONS, SHOCKS, AND RINGS

Energy Technology Data Exchange (ETDEWEB)

Conn, Blair C. [Gemini Observatory, Recinto AURA, Colina El Pino, Casilla 603, La Serena (Chile); Fogarty, L. M. R. [Sydney Institute for Astronomy, School of Physics, The University of Sydney, A28, Sydney, 2006 (Australia); Smith, Rory [Yonsei University, Graduate School of Earth System Sciences-Astronomy-Atmospheric Sciences, Yonsei-ro 50, Seoul 120-749 (Korea, Republic of); Candlish, Graeme N., E-mail: bconn@gemini.edu [Departamento de Astronomía, Universidad de Concepción, Casilla 160-C, Concepción (Chile)

2016-03-10

We present Multi Unit Spectroscopic Explorer observations of AM1354-250, confirming its status as a collisional ring galaxy that has recently undergone an interaction, creating its distinctive shape. We analyze the stellar and gaseous emission throughout the galaxy finding direct evidence that the gaseous ring is expanding with a velocity of ∼70 km s{sup −1} and that star formation is occurring primarily in H ii regions associated with the ring. This star formation activity is likely triggered by this interaction. We find evidence for several excitation mechanisms in the gas, including emission consistent with shocked gas in the expanding ring and a region of LINER-like emission in the central core of the galaxy. Evidence of kinematic disturbance in both the stars and gas, possibly also triggered by the interaction, can be seen in all of the velocity maps. The ring galaxy retains a weak spiral structure, strongly suggesting the progenitor galaxy was a massive spiral prior to the collision with its companion an estimated 140 ± 12 Myr ago.

Restor(y)ing Hope: Stories as Social Movement Learning in Ada Songor Salt Movement

Science.gov (United States)

Langdon, Jonathan; Garbary, Rachel

2017-01-01

Stories are a central component of how we understand ourselves and our societies in our world. This is especially true in the case of oral cultures. Stories, how they are used, how they are reframed, and how they change over time, are also an important record of learning. Randall (1996) and Kenyon and Randall (1997) have called this process…

Hydrothermal alteration studies of gabbros from northern central Indian ridge and their geodynamic implications

Digital Repository Service at National Institute of Oceanography (India)

Ray, Dwijesh; Mevel, C.; Banerjee, R.

, IPGP, 4 Place Jussieu, F-75252 Paris Cedex 5, France. 3 National Institute of Oceanography, Goa 403 004, India. ∗ e-mail: dwijesh@rediffmail.com Mylonitic gabbro and altered gabbro were recovered from off-axis high and corner high loca- tions at ridge... microprobe analyzer at the CAMPARIS service of the IPG-Paris (University of Paris 6, France). Analytical conditions used were 15 kV accelerating voltage, 20 nA beam current and 20–40 s count- ing times. All analyses were performed in a point mode. A 2–3 µm...

Centralized vs. De-centralized Multinationals and Taxes

DEFF Research Database (Denmark)

Nielsen, Søren Bo; Raimondos-Møller, Pascalis; Schjelderup, Guttorm

2005-01-01

The paper examines how country tax differences affect a multinational enterprise's choice to centralize or de-centralize its decision structure. Within a simple model that emphasizes the multiple conflicting roles of transfer prices in MNEs - here, as a strategic pre-commitment device and a tax...

GLOBAL FINANCIAL CRISIS AND UNIT-LINKED INSURANCE MARKETS EFFICIENCY: EMPIRICAL EVIDENCE FROM CENTRAL AND EASTERN EUROPEAN COUNTRIES

Directory of Open Access Journals (Sweden)

Botoş Horia Mircea

2012-12-01

Full Text Available This paper empirically investigates the impact of the Global financial crisis on the efficiency of four Central and Eastern European emerging unit-linked insurance markets, applying the automatic variance ratio (AVR test of Kim (2009 and variance ratio tests using ranks and signs by Wright (2000 for entire, pre-crisis and crisis periods. This study contributes to the existing literature on efficient market hypothesis with several distinct features: it provides a systematic review of the weak-form market efficiency literature that examines return predictability of the daily ING unit-linked funds prices; also the article aims at monitoring any improvement in the degree of efficiency in time and also examines the relative efficiency of unit-linked insurance markets in pre-crisis and crisis periods. Unit linked insurance are life insurance policies with investment component. In the literature there are few studies investigating the effects of a financial crisis on the potential of predictability and implicitly on the degree of efficiency of financial markets. The occurrence of a market crash or financial crisis is a possible contributing factor of market inefficiency. Most of the studies are focused on the Asian crisis in 1997: Holden et al. (2005 examined the weak-form efficiency of eight emerging Asian stock markets using VR tests before, during and after the Asian crisis; Kim and Shamsuddin (2008 used three different types of multiple VR tests for nine Asian stock markets; the findings reported by Lim et al. (2008 are consistent with those reported by Cheong et al. (2007, in which the highest inefficiency occurs during the crisis period. Todea and Lazar (2010 investigated the effects of the Global crisis on the relative efficiency of ten CEE stock markets, using Generalized Spectral test of Escanciano and Velasco (2006. Wright (2000 proposes the alternative non-parametric variance ratio tests using ranks and signs of return and demonstrates that

Green(ing) infrastructure

CSIR Research Space (South Africa)

Van Wyk, Llewellyn V

2014-03-01

Full Text Available the generation of electricity from renewable sources such as wind, water and solar. Grey infrastructure – In the context of storm water management, grey infrastructure can be thought of as the hard, engineered systems to capture and convey runoff..., pumps, and treatment plants.  Green infrastructure reduces energy demand by reducing the need to collect and transport storm water to a suitable discharge location. In addition, green infrastructure such as green roofs, street trees and increased...

Ocorrência e aspectos ecológicos de metazoários parasitos de peixes do Lago do Parque do Ingá, Maringá, Estado do Paraná - DOI: 10.4025/actascibiolsci.v29i3.507 Occurrence and ecological aspects of the metazoan fish parasites from Ingá lake, Maringá, Paraná State - DOI: 10.4025/actascibiolsci.v29i3.507

Directory of Open Access Journals (Sweden)

Marion Haruko Machado

2007-12-01

Full Text Available Nenhum estudo de peixes e parasitos foi realizado, até o momento, no Lago do Parque do Ingá que sofre influências antrópicas desde seu represamento, em 1970. Este trabalho analisou alguns aspectos ecológicos dos parasitos metazoários dos peixes deste lago. Dos peixes analisados, (69,5% estavam parasitados por pelo menos uma espécie de parasito. Foram encontrados 1.372 parasitos pertencentes à Nematoda (larvas e Platyhelminthes (Monogenea e Cestoda, sendo estes os mais prevalentes e numerosos. O encontro de larvas de cestóides em Tilapia rendalli e Oreochromis niloticus confirma a importância destas espécies como participantes de níveis tróficos intermediários. A maior abundância de T. rendalli e O. niloticus, no local, pode ser um fator determinante no recrutamento de parasitos. O parasito aproveita-se das espécies de hospedeiros mais abundantes para garantir o desenvolvimento de seu ciclo de vida e também por serem os mais disponíveis à predação pelas aves piscívoras ali presentes, o que torna o local de grande importância para a sustentação do ciclo de vida desses parasitos. A baixa diversidade de endoparasitos coletados pode ser justificada pela presença de metais pesados – Cu e Pb – no sedimento, o que deve estar interferindo no desenvolvimento dos invertebrados, possíveis hospedeiros intermediários.Ingá lake was dammed in 1970 and, since then, no study on fish and parasites had been done, but it has suffered anthropic influences. This study analyzed some ecological aspects of the metazoan parasites form this lake. From analyzed fish, 69.5% had at least one species of parasite. Among them, 1.372 parasites were found, prevailing Nematoda (larvae and Platyhelminthes (Monogenea and Cestoda. The discovery of cestode larvae in Tilapia rendalli and Oreochromis nitolicus confirms the importance of these species as participants of intermediate trophic levels. The great number of Tilapia rendalli and Oreochromis

Response of zooplankton to physical changes in the environment: coastal upwelling along central west coast of India

Digital Repository Service at National Institute of Oceanography (India)

Madhupratap, M.; Nair, S.R.S.; Haridas, P.; Padmavati, G.

.U. Haq and J.D. Milliman, (Eds.), Marine Geology and Oceanography ofArabian Sea and Coastal Pakistan. New York: Reinhold, pp. 339-350. PAFFENHOFER, G-A.; WESTER, B.T. and NICHO· LAS, W.O., 1984. Zooplankton abundance in rela- Journal of Coastal Research... Ocean. Proceedings of the Indian Academy of Sciences, 94, 129-137. SMITH, S.L., 1982. The northwest Indian Ocean dur ing the monsoons of 1979: distribution, abundance and feeding of zooplankton. Deep-Sea Research, 29, 1331-1353. SMITH, S.L.; BOYQ, C...

Penstock failure detection system at the 'Valsan' hydro power plant

International Nuclear Information System (INIS)

Georgescu, A M; Coşoiu, C I; Alboiu, N; Hlevca, D; Tataroiu, R; Popescu, O

2012-01-01

'Valsan' is a small Hydro Power Plant, 5 MW, situated at about 160 km north of Bucharest, Romania, on the small 'Valsan' river in a remote mountainous area. It is equipped with a single Francis turbine. The penstock is located in the access shaft of the HPP. 'Hidroelectrica', the Romanian company that operates the HPP, was trying to implement a remote penstock failure detection system. Starting from a classic hydraulic problem, the authors of the paper derived a method for failure detection and localization on the pipe. The method assumes the existence of 2 flow meters and 2 pressure transducers at the inlet and outlet of the pressurized pipe. Calculations have to be based on experimental values measured in a permanent regime for different values of the flow rate. The method was at first tested on a pipe, in the Hydraulic Laboratory of the Technical University of Civil Engineering Bucharest. Pipe failure was modelled by opening of a valve on a tee branch of the analyzed pipe. Experimental results were found to be in good agreement with theoretical ones. The penstock of the 'Valsan' HPP, was modelled in EPANET, in order to: i) test the method at a larger scale; ii) get the right flow and pressure transducers that are needed to implement it. At the request of 'Hidroelectrica' a routine that computes the efficiency of the turbine was added to the monitoring software. After the system was implemented, another series of measurements were performed at the site in order to validate it. Failure was modelled by opening an existing valve on a branch of the penstock. Detection of the failure was correct and almost instantaneous, while failure location was accurate within 5% of the total penstock length.

Penstock failure detection system at the "Valsan" hydro power plant

Science.gov (United States)

Georgescu, A. M.; Coşoiu, C. I.; Alboiu, N.; Hlevca, D.; Tataroiu, R.; Popescu, O.

2012-11-01

"Valsan" is a small Hydro Power Plant, 5 MW, situated at about 160 km north of Bucharest, Romania, on the small "Valsan" river in a remote mountainous area. It is equipped with a single Francis turbine. The penstock is located in the access shaft of the HPP. "Hidroelectrica", the Romanian company that operates the HPP, was trying to implement a remote penstock failure detection system. Starting from a classic hydraulic problem, the authors of the paper derived a method for failure detection and localization on the pipe. The method assumes the existence of 2 flow meters and 2 pressure transducers at the inlet and outlet of the pressurized pipe. Calculations have to be based on experimental values measured in a permanent regime for different values of the flow rate. The method was at first tested on a pipe, in the Hydraulic Laboratory of the Technical University of Civil Engineering Bucharest. Pipe failure was modelled by opening of a valve on a tee branch of the analyzed pipe. Experimental results were found to be in good agreement with theoretical ones. The penstock of the "Valsan" HPP, was modelled in EPANET, in order to: i) test the method at a larger scale; ii) get the right flow and pressure transducers that are needed to implement it. At the request of "Hidroelectrica" a routine that computes the efficiency of the turbine was added to the monitoring software. After the system was implemented, another series of measurements were performed at the site in order to validate it. Failure was modelled by opening an existing valve on a branch of the penstock. Detection of the failure was correct and almost instantaneous, while failure location was accurate within 5% of the total penstock length.

China’s Rise and Reconfiguration of Central Asia’s Geopolitics: A Case for U.S. Pivot to Eurasia

Science.gov (United States)

2015-07-01

modities, real estate, luxury goods , and cyber hack- ing. First and foremost, China would need to address economic, social, and environmental challenges...China’s eco- nomic growth model changes from the one predomi- nantly based on savings and exports to the one based largely on domestic consumption ...power given its presence in Afghanistan. But these powers are not without their own chal- lenges, and that has been good news for China. Rus- sia’s

A tectonomagnetic effect detected in Central Italy

Directory of Open Access Journals (Sweden)

P. Palangio

1994-06-01

Full Text Available Significant variations in the absolute value of the geomagnetic field intensity related to tectonic events, as earthquakes and volcanic eruptions, have been observed in several cases. To detect such a tectonomagnetic effect related to seismic activity, a seismomagnetic network was installed by the Istituto Nazionale di Geofisica (ING in the Abruzzi region (CentraI Italy, in July 1989. This area is being uplifting since the Pliocene. A logistic compromise between geophysical requirements and the electrified railway system tracks distribution led to the installation of five total magnetic field intensity data acquisition sites. From July 1989 to September 1992 geomagnetic intensity data were simultaneously recorded at all stations and compared to that recorded at the L'Aquila Observatory, located in the same area. A variation of about 10 nT in the absolute level of the geomagnetic field was measured at two stations located on the eastern side of the network. We suggest that the detected magnetic anomaly could resuIt from aseismic-changes in crustal stress during this time.

Výzkum lokality Sfinga (SBK.W-60 v pohoří Sabaloka v centrálním Súdánu: poznatky z výzkumné sezóny 2014 // Exploration of the site of Sphinx (SBK.W-60 at Jebel Sabaloka in Central Sudan: findings of the 2014 field campaign

Directory of Open Access Journals (Sweden)

Lenka Varadzinová Suková

2015-06-01

Full Text Available In the autumn of 2014, the interdisciplinary mission directed by the Czech Institute of Egyptology carried out its third excavation campaign at Jebel Sabaloka (West Bank. The site has been explored for remains of prehistoric occupation since 2011. A comparatively small area (7.50 m2 was explored in detail at the site of Sphinx (SBK.W-60 with the aim of identifying settlement layers and features, investigat - ing archaeological formation processes in co-operation with geologists and sedimentologists, and defining future meth - ods and procedures for exploration of prehistoric sites at Jebel Sabaloka. In addition to a number of important finds, several findings of methodological significance were made that contribute to the topical discussion on the character of cultural deposits of prehistoric dating in the Central Sudan and the possibilities and limitations of their stratigraphic excavation by means of traditional archaeological methods.

Is banking supervision central to central banking?

OpenAIRE

Joe Peek; Eric S. Rosengren; Geoffrey M. B. Tootell

1997-01-01

Whether central banks should play an active role in bank supervision and regulation is being debated both in the United States and abroad. While the Bank of England has recently been stripped of its supervisory responsibilities and several proposals in the United States have advocated removing bank supervision from the Federal Reserve System, other countries are considering enhancing central bank involvement in this area. Many of the arguments for and against these proposals hinge on the effe...

Repeated Treatments with Ingenol Mebutate Prevents Progression of UV-Induced Photodamage in Hairless Mice

DEFF Research Database (Denmark)

Erlendsson, Andrés Már; Thaysen-Petersen, Daniel; Bay, Christiane

2016-01-01

BACKGROUND AND AIM: Ingenol mebutate (IngMeb) is an effective treatment for actinic keratosis. In this study, we hypothesized that repeated treatments with IngMeb may prevent progression of UV-induced photodamage, and that concurrent application of a corticosteroid may reduce IngMeb-induced local...... once daily for 5 days prior to each IngMeb application, as well as 6 h and 1 day post treatment. One week after IngMeb treatment No. 1, 3, and 5 (Days 28, 84, and 140), biopsies from four mice in each group were collected for histological evaluation of UV-damage on a standardized UV-damage scale (0......-12). LSR (0-24) were assessed once daily (Days 1-7) after each IngMeb treatment. RESULTS: IngMeb prevented progression of photodamage in terms of keratosis grade, epidermal hypertrophy, dysplasia, and dermal actinic damage with a lower composite UV-damage score on day 140 (UVR 10.25 vs. UVR+IngMeb 6.00, p...

Reactivation of latent HIV-1 by new semi-synthetic ingenol esters

Energy Technology Data Exchange (ETDEWEB)

Pandeló José, Diego [Departamento de Genética, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902 (Brazil); Bartholomeeusen, Koen [Department of Medicine, Microbiology and Immunology, University of California at San Francisco, San Francisco, CA 94143-0703 (United States); Delveccio da Cunha, Rodrigo; Abreu, Celina Monteiro [Departamento de Genética, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902 (Brazil); Glinski, Jan [PlantaAnalytica LLC, Danbury, CT 06810 (United States); Barbizan Ferreira da Costa, Thais; Bacchi Rabay, Ana Flávia Mello; Pianowski Filho, Luiz Francisco [Kyolab Laboratories, Valinhos, São Paulo 13273-105 (Brazil); Dudycz, Lech W. [Lex Company Research Laboratories, Shirley 01464, MA (United States); Ranga, Udaykumar [Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru 560064 (India); Peterlin, Boris Matija [Department of Medicine, Microbiology and Immunology, University of California at San Francisco, San Francisco, CA 94143-0703 (United States); Pianowski, Luiz Francisco [Kyolab Laboratories, Valinhos, São Paulo 13273-105 (Brazil); Tanuri, Amilcar [Departamento de Genética, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902 (Brazil); Aguiar, Renato Santana, E-mail: santana@biologia.ufrj.br [Departamento de Genética, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902 (Brazil)

2014-08-15

The ability of HIV to establish long-lived latent infection is mainly due to transcriptional silencing of viral genome in resting memory T lymphocytes. Here, we show that new semi-synthetic ingenol esters reactivate latent HIV reservoirs. Amongst the tested compounds, 3-caproyl-ingenol (ING B) was more potent in reactivating latent HIV than known activators such as SAHA, ingenol 3,20-dibenzoate, TNF-α, PMA and HMBA. ING B activated PKC isoforms followed by NF-κB nuclear translocation. As virus reactivation is dependent on intact NF-κB binding sites in the LTR promoter region ING B, we have shown that. ING B was able to reactivate virus transcription in primary HIV-infected resting cells up to 12 fold and up to 25 fold in combination with SAHA. Additionally, ING B promoted up-regulation of P-TEFb subunits CDK9/Cyclin T1. The role of ING B on promoting both transcription initiation and elongation makes this compound a strong candidate for an anti-HIV latency drug combined with suppressive HAART. - Highlights: • 3-caproyl-ingenol (ING B) reactivates latent HIV better than SAHA, ingenol 3,20-dibenzoate, TNF-α, PMA and HMBA. • ING B promotes PKC activation and NF-kB translocation to the nucleus. • ING B activates virus transcription of B and non-B subtypes of HIV-1. • ING B activates HIV transcription in infected primary resting CD4+ T cells. • ING B induces higher levels of P-TEFb components in human primary cells.

Central Nervous System Vasculitis

Science.gov (United States)

... of Vasculitis / Central Nervous System (CNS) Vasculitis Central Nervous System (CNS) Vasculitis Swap out your current Facebook Profile ... Facebook personal page. Replace with this image. Central nervous system (CNS) vasculitis is inflammation of blood vessel walls ...

Outsourcing central banking

DEFF Research Database (Denmark)

Khoury, Sarkis Joseph; Wihlborg, Clas

2005-01-01

The literature on Currency Boards (CB) stops at the water edge in terms of dealing with the totality of the functions of a central bank. Monetary policy, and banking supervisioncan be "outsourced" in an open economy with substantial foreign direct investment (FDI)in the banking sector if political...... nationalism does not trump economic rationality. An orthodox CB renders the central banking function redundant in terms of interest rate and exchange rate determination. FDI in banking could perform the same role for the supervisory function of central banks. We use the case of Estonia to illustrate...... the feasibility of, and constraints on, outsourcing of central bank functions. A brief discussion of the Argentinian experience is used for contrast.Key words: Currency Board, Foreign Banks, Supervision, Regional Integration,outsourcing....

NIDDK Central Repository

Data.gov (United States)

U.S. Department of Health & Human Services — The NIDDK Central Repository stores biosamples, genetic and other data collected in designated NIDDK-funded clinical studies. The purpose of the NIDDK Central...

EDITORIAL, FOREWORD

Directory of Open Access Journals (Sweden)

Editorial Foreword

2017-06-01

Full Text Available Biomaterials and SurfacesSeptember 20th-23th, 2016Herbertov, Czech RepublicOrganized by:Department of Materials Engineering, Faculty of Mechanical Engineering, Czech Technical University in PragueInstitute of Rock Structure and Mechanics AS CRSociety for composite and carbon materialsGuest editor: Ing. Zdeněk ToldeThe colloquium "Biomaterials and surfaces" focuses on methods for biocompatibility testing and methods for characterization and modification of biomaterials and their surfaces. The goal of this seminar is to inform the participants about fundamental problematic of biomaterials and the recent state of research and development of prostheses or artificial replacements in Czech Republic. At the seminar, participants and students are meeting with the scientific capacities in the field of biomaterials and surfaces (materials engineering, medicine, physics, chemistry, biology and with the experts from practice (doctors, representatives of leading Czech companies in the industry.Scientific comitee:Doc. RNDr. Vladimír Starý CSc. (Faculty of Mechanical EngineeringIng. Karel Balík, CSc. (Society for composite and carbon materialsIng. Tomáš Suchý Ph.D. (Institute of Rock Structure and Mechanics AS CR Ing. Radek Sedláček Ph.D. (Faculty of Mechanical Engineering Ing. Zdeněk Tolde (Faculty of Mechanical EngineeringGuarantors of peer review process: Prof. RNDr. Petr Špatenka CSc. (Faculty of Mechanical Engineering Doc. RNDr. Vladimír Starý CSc. (Faculty of Mechanical Engineering Ing. Tomáš Suchý Ph.D. (Institute of Rock Structure and Mechanics AS CR Doc. RNDr. Václav Nehasil, Dr. (Faculty of Mathematics and Physics RNDr. Marta Vandrovcová, Ph.D. (Institute of Physiology CAS Guarantor of language editing:Ing. Stanislav Krum PhD.Organizing comitee: Ing. Karel Balík, CSc. RNDr. Martin Braun, Ph.D. Ing. Ladislav Cvrček Ph.D. Ing. Zdeňka Jeníková Ph.D. Ing. Radek Sedláček Ph.D. Doc. RNDr. Vladimír Starý CSc. Ing. Tomáš Such

CENTRAL PLATEAU REMEDIATION

International Nuclear Information System (INIS)

ROMINE, L.D.

2006-01-01

A systematic approach to closure planning is being implemented at the Hanford Site's Central Plateau to help achieve the goal of closure by the year 2035. The overall objective of Central Plateau remediation is to protect human health and the environment from the significant quantity of contaminated material that resulted from decades of plutonium production in support of the nation's defense. This goal will be achieved either by removing contaminants or placing the residual contaminated materials in a secure configuration that minimizes further migration to the groundwater and reduces the potential for inadvertent intrusion into contaminated sites. The approach to Central Plateau cleanup used three key concepts--closure zones, closure elements, and closure process steps--to create an organized picture of actions required to complete remediation. These actions were merged with logic ties, constraints, and required resources to produce an integrated time-phased schedule and cost profile for Central Plateau closure. Programmatic risks associated with implementation of Central Plateau closure were identified and analyzed. Actions to mitigate the most significant risks are underway while high priority remediation projects continue to make progress

"out of The Cold": On Late Neanderthal Population Dynamics In Central Europe

Science.gov (United States)

Jöris, O.

During the last several years, analyses of fossil Neanderthal DNA have shown not only the degree to which the genetic fingerprints of Neanderthals differ from those of anatomically modern humans, but have also lent credibility to the hotly debated "Out- of-Africa" hypothesis. Perhaps more important than the observed genetic differences is the fact that Neanderthals - according to their reconstructed DNA sequences - were genetically highly homogeneous, indicating rapid population growth that may have followed a demographic 'bottleneck' during the first cold maximum (CM-1 = second part of OIS 4) of the last glacial, some 60 to 70 ka ago. Central European Middle Palaeolithic sites characterised by broad spectra of bifacially-worked tools, namely different forms of backed knives ("Keilmesser") com- monly attributed to Neanderthals, fall within the age-range 85 and 45 ka calBP and thus both pre- and post-date the proposed 'bottleneck' that occurred during CM-1. Di- rectly comparable sites dating within this critical period are lacking. Based on strati- graphic, palaeoenvironmental, and radiometric evidence, a series of sites can tenta- tively be age-calibrated with the high-resolution GISP2 Greenland ice core record of last glacial climate change. With the aid of improved chronological frameworks and additional palaeoenvironmen- tal information (e.g. glacier mass balance models), we have developed a three-step model with which to investigate this period. We begin with (1) pre-CM-1 populations in Central and northern Central Europe which (2) were forced into southern Euro- pean refugia (i.e. SW France and the Pannonian Basins) by the rapid expansion of the northern hemispheric ice-cover at the beginning of CM-1 (a process that could be named 'preglacial dislocation'). Finally, some 10 ka later, their descendants may have re-occupied the southern part of Central Europe during the climatic amelioration (OIS 3) following CM-1. Changes in lithic technology, as expressed in

Actual versus Perceived Central Bank Transparency : The Case of the European Central Bank

NARCIS (Netherlands)

van der Cruijsen, C.A.B.; Eijffinger, S.C.W.

2007-01-01

Central banks have become more and more transparent about their monetary policy making process. In the central bank transparency lit- erature the distinction between actual and perceived central bank trans- parency is often lacking. However, as perceptions are crucial for the ac- tions of economic

A paradigm shift for radical SAM reactions: The organometallic intermediate Ω is central to catalysis.

Science.gov (United States)

Byer, Amanda S; Yang, Hao; McDaniel, Elizabeth C; Kathiresan, Venkatesan; Impano, Stella; Pagnier, Adrien; Watts, Hope; Denler, Carly; Vagstad, Anna; Piel, Jörn; Duschene, Kaitlin S; Shepard, Eric M; Shields, Thomas P; Scott, Lincoln G; Lilla, Edward A; Yokoyama, Kenichi; Broderick, William E; Hoffman, Brian M; Broderick, Joan B

2018-06-28

Radical S-adenosyl-L-methionine (SAM) en-zymes comprise a vast superfamily catalyzing diverse reactions essential to all life through ho-molytic SAM cleavage to liberate the highly-reactive 5-deoxyadenosyl radical (5-dAdo•). Our recent observation of a catalytically compe-tent organometallic intermediate Ω that forms dur-ing reaction of the radical SAM (RS) enzyme py-ruvate formate-lyase activating-enzyme (PFL-AE) was therefore quite surprising, and led to the question of its broad relevance in the superfamily. We now show that Ω in PFL-AE forms as an in-termediate under a variety of mixing order condi-tions, suggesting it is central to catalysis in this enzyme. We further demonstrate that Ω forms in a suite of RS enzymes chosen to span the totality of superfamily reaction types, implicating Ω as essential in catalysis across the RS superfamily. Finally, EPR and electron nuclear double reso-nance spectroscopy establish that Ω involves an Fe-C5 bond between 5-dAdo• and the [4Fe-4S] cluster. An analogous organometallic bond is found in the well-known adenosylcobalamin (co-enzyme B12) cofactor used to initiate radical reac-tions via a 5'-dAdo• intermediate. Generation of a 5'-dAdo• intermediate via homolytic metal-carbon bond cleavage thus appears to be similar for Ω and coenzyme B12. However coenzyme B12 is involved in enzymes catalyzing of only a small number (~12) of distinct reactions, while the RS superfamily has more than 100,000 distinct se-quences and over 80 reaction types character-ized to date. The appearance of Ω across the RS superfamily therefore dramatically enlarges the sphere of bio-organometallic chemistry in Nature.

SECURITY THREATS IN CENTRAL ASIA

Directory of Open Access Journals (Sweden)

Çağla Gül Yesevi

2013-07-01

Full Text Available This study will analyze main security threats in Central Asia. It is obvious thatsince the end of Cold War, there have been many security threats in Central Asiaas internal weakness of Central Asian states, terrorism, transnational crime,economic insecurity, environmental issues, drug trafficking, ethnic violence,regional instability. This study will propose thatwith increasing interdependence,states need each other to solve these global security problems. In that sense,regional and sub-regional cooperation between Central Asian states and with otherregional actors has been witnessed. It is clear that the withdrawal of NATO fromAfghanistan will destabilize Central Asia. This study will investigate overallsecurity situation in Central Asia and affects andcontributions of regionalorganizations to Eurasian security

L'épistémologie et l'histoire des sciences et des techniques peuvent elles aider les futurs enseignants de sciences physiques dans l'exercice de leur métier ? Regards portés pour une ingénierie de formation

Directory of Open Access Journals (Sweden)

Guedj Muriel

2014-01-01

Full Text Available Cette étude interroge la place de l'Epistémologie, l'Histoire des Sciences et des Techniques comme élément pertinent pour améliorer la professionnalité des enseignants de sciences physiques. La réflexion se nourrit des nouvelles orientations prises au sein d'écoles d'ingénieurs et de facultés de médecine qui ont fait le choix d'introduire des unités d'enseignement dédiées aux Sciences Humaines et Sociales afin de perfectionner la qualité professionnelle de leurs formations. Une étude de cas dédiée à l'enseignement de l'énergie illustre le propos.

Demographic tensions in Central America.

Science.gov (United States)

1986-08-01

This discussion of Central America focuses on the rapid growth of its population, its stagnating economy, and those countries that are socioeconomically advanced. Between 1950-85 the population of Central America tripled, from 9.1 million to 26. 4 million, due to marked mortality declines and the absence of off-setting fertility declines. The distribution of Central Americas's growing populations sets its population growth apart from that of other developing regions. Currently, almost half of all Central Americans live in cities. Although the average growth rate for Central American countries has fallen and is expected to drop further, the decline does not counterbalance the effect of the absolute rise in population numbers. The average annual growth rate of more than 3% annually in the 1960s fell to about 2.6% in recent years, but this decline is due primarily to socioeconomically advanced Costa Rica and Panama. Central America's age structure further complicates the population crisis. About 43% of Central Americans are under the age of 15. When the increasingly larger young population group enters it reproductive years, the potential for future growth (albeit the falling rate of population increase) is unparalleled. UN population projections show the region's population at 40 million by the year 2000. The 1973 oil crisis began a downward spiral for the buoyant post World War II Central American economy. Between 1950-79, real per capita income growth in Central America doubled, with Central American economies growing an average of 5.3% annually. By the early 1980s, overseas markets of the trade-dependent countries of Central America had dried up due to protectionism abroad and slumping basic commodity prices. These and other factors plunged Central America into its current economic malaise of falling real per capita income, rising unemployment, curtailed export led economic growth, and a rising cost of living. In general, economic growth in Central America

Mercury pOIsonIng

African Journals Online (AJOL)

A case of mercury poisoning is reported and clinical observations of 6 .... fish ingested and occupational exposure. .... exposed to mercury as a result of inadequate industrial safety standards, and ... WHO Tech Rep Ser 1980; No. 674: 102-115.

Hollandi pank soovitab Eesti Telekomi müüa / Annika Matson

Index Scriptorium Estoniae

Matson, Annika, 1976-

2004-01-01

Hollandi investeerimispanga ING jt pankade analüütikute soovitused tehinguteks Eesti Telekomi aktsiatega. Graafik: Telekomi aktsia on ING arvates ligi neljandiku võrra ülehinnatud. Vt. samas: ING-l on üle maailma 60 miljonit klienti

Studies on the Optimal behavior of Energy Storage in Reservoirs of a Hydroelectric system; Estudios sobre el comportamiento optimo del almacenamiento de energia en embalses de sistema hidroelectrico

Energy Technology Data Exchange (ETDEWEB)

Macedo Faria, Breno; Franco Barbosa, Paulo Sergio [Universidad Estatal de Campinas (Brazil)

2002-09-01

This work aims at studying the results of an optimisation model applied to the Paranaiba river basin, Brazil. This system is made by the junction of three river branches located in a region with a well-defined seasonal hydrological behavior. The ratio between the total energy storage in the system and the active storage for every reservoir is evaluated from the optimal operational results. This relationship allows recognizing systematic patterns on the relative use for every reservoir, when compared to the entire system. The main parameters that define reservoir behavior are identified, with highlights on the position of the power station in the cascade, the relationship between the river flow and the active storage, and the installed capacity of the power station. In addition, the parameter hydrological scenario is also another factor that defines the relative use of the reservoirs. [Spanish] El modelo del presente trabajo tiene como objetivo estudiar los resultados de una optimizacion para el sistema hidroelectrico de la cuenca del rio Paranaiba, Brasil, la cual esta formada por la confluencia de tres rios en una region de distribucion de lluvias bien definidas en terminos hidrologicos. Se analiza la relacion entre la energia total almacenada en el sistema y el volumen util de cada embalse a partir de los resultados operativos optimos. Esta relacion permite identificar resultados sistematicos en lo que se refiere a la utilizacion de cada embalse, en comparacion con el uso del sistema como un todo. Se identifican los principales parametros responsables por el comportamiento de los embalses, destacando la influencia de la posicion de la central hidroelectrica en la cascada, de la relacion caudal/volumen util y de la potencia de central. Ademas, el parametro escenario hidrologico tambien es otro factor determinante en el uso relativo de los embalses.

Europa central

Directory of Open Access Journals (Sweden)

Karel BARTOSEK

2010-02-01

Full Text Available La investigación francesa continúa interesándose por Europa Central. Desde luego, hay límites a este interés en el ambiente general de mi nueva patria: en la ignorancia, producto del largo desinterés de Francia por este espacio después de la Segunda Guerra Mundial, y en el comportamiento y la reflexión de la clase política y de los medios de comunicación (una anécdota para ilustrar este ambiente: durante la preparación de nuestro coloquio «Refugiados e inmigrantes de Europa Central en el movimiento antifascista y la Resistencia en Francia, 1933-1945», celebrado en París en octubre de 1986, el problema de la definición fue planteado concreta y «prácticamente». ¡Y hubo entonces un historiador eminente, para quién Alemania no formaría parte de Europa Central!.

Central Banking after the Crisis

OpenAIRE

Frederick S. Mishkin

2013-01-01

This paper explores where central banking is heading after the recent financial crisis. First it discusses the central bank consensus before the crisis and then outlines the key facts learned from the crisis that require changes in the way central banks conduct their business. Finally, it discusses four main areas in which central banks are altering their policy frameworks: 1) the interaction between monetary and financial stability policies, 2) nonconventional monetary policy, 3) risk manage...

Central ignition scenarios for TFTR

International Nuclear Information System (INIS)

Zweben, S.J.; Redi, M.H.; Bateman, G.

1986-03-01

The possibility of obtaining ignition in TFTR by means of very centrally peaked density profiles is examined. It is shown that local central alpha heating can be made to exceed local central energy losses (''central ignition'') under global conditions for which Q greater than or equal to 1. Time dependent 1-D transport simulations show that the normal global ignition requirements are substantially relaxed for plasmas with peaked density profiles. 18 refs., 18 figs

Priesagos -ng- prūsų hidronimai

Directory of Open Access Journals (Sweden)

Feliksas Daubaras

2011-12-01

Full Text Available DIE ALTPREUßlSCHEN HYDRONYME MIT -ng- SUFFIXENZusammenfassungIm vorliegenden Artikel werden altpr. Gewässernamen mit den Suffixen –ing- und -ang- besprochen. Hydronyme mit -ing- sind ihrer Herkunft nach Adjektive, die meistens von Substantiven ab­geleitet sind und den Besitz des durch das Stammwort ausgedrückten Begriffes bezeichnen. Manche von ihnen sind zu Eigennamen geworden, z. B. altpr. rag-ingis „Hirsch“ „mit Hörnern“ = *Rag-ing- Fluß, vgl. altpr. ragis „Horn“, lit. rãgas „Horn, Landzunge“; altpr. *stab-ing- „steinig“ = *Stab­-ing- See, vgl. altpr. stabis „Stein“; altpr. *sil-ing- „von Heiden umgeben“ = *Sil-ing- Bach, vgl. altpr. sylo „Heide“. Insgesamt sind im Artikel einunddreißig Hydronyme mit -ing- und drei mit -ang- angeführt. Die Konzentration von Gewässer- bzw. Ortsnamen mit diesen Suffixen in altpreussischen, kurischen und selischen Gebieten hat bereits Būga bemerkt. Das Suffix -ing- bei der Bil­dung von Gewässernamen war ursprünglich wohl nur den westlichen baltischen Stämmen (Preußen und Jatwingen und ihren nächsten Nachbarn Kuren bekannt. Das Suffix -ang- ist nur für Kuren und Preußen typisch. Hydronymische Parallelen mit Wurzeln von altpr. Gewässernamen mit -ing-und -ang- sind in Litauen und Lettland verschieden verbreitet. Mehrere von ihnen sind auf dem ganzen litauischen und lettischen Territorium zu treffen, z, B. *Amel-, *Ard-, *Ar-, *Bal-, *Bert-,*Birkel- , *Dubr-, *Eiv-, *Gisl-, *Kukul-, *Mat-, *Mus-, * Mutet-, *Mar-, *Rag-, *Ser-, *Sil-, *Sav-, *Ulp-, *Vad-. Manche Wurzeln kommen nur in bestimmten Gebieten vor, z. B. *Erl-,*Ranz-, *Skutel- — in Kurland, *Stab- — in Jatwingien, *Īz— in Selenland.Einige altpr. Hydronyme mit -ing- haben Variante mit -ung- (Amel-ink: Amelung, Dalwinge: Dalwunge, Seringe: Serung, was sich durch den Einfluß der deutschen Sprache deuten läßt.

Colloquium on Central Asia; Colloque sur l'Asie centrale

Energy Technology Data Exchange (ETDEWEB)

NONE

2005-07-01

This colloquium on Azerbaijan was organized by the direction of international relations of the French Senate and the French center of foreign trade (CFCE). This document gathers the interventions of the participants and the debates with the audience following these interventions. The topics treated concern: - the present day political-economical situation of Central Asia countries (problem of borders, relations with Russia and China); - the economies of Central Asia countries: short term problems and medium-term perspectives; - the relations with the European Union (political, economical, trade and investments, perspectives); - the European energy stakes of Caspian sea (oil and gas reserves, development of hydrocarbon resources, exploitation and transport constraints, stakes for Europe and France); - TotalFinaElf company in Central Asia (Kazakhstan, Azerbaijan, enclavement problem); - the economical impacts of the TRACECA pathway (Transport Corridor Europe Caucasus Asia). (J.S.)

The fashion blog as genre

DEFF Research Database (Denmark)

Engholm, Ida; Hansen-Hansen, Erik

2013-01-01

- ing them into new formats, where amateur bricolage approaches are combined with the reproduction of fam- iliar features from the established fashion media. The article presents four types of fashion blogs, each represent- ing a specific design strategy for presenting and interact- ing with fashion...

Alpha current flow betweenness centrality

NARCIS (Netherlands)

Avrachenkov, K.; Litvak, Nelli; Medyanikov, V.; Sokol, M.

2013-01-01

A class of centrality measures called betweenness centralities reflects degree of participation of edges or nodes in communication between different parts of the network. The original shortest-path betweenness centrality is based on counting shortest paths which go through a node or an edge. One of

Observations of central stars

International Nuclear Information System (INIS)

Lutz, J.H.

1978-01-01

Difficulties occurring in the observation of central stars of planetary nebulae are reviewed with emphasis on spectral classifications and population types, and temperature determination. Binary and peculiar central stars are discussed. (U.M.G.)

[Central diabetes insipidus: diagnostic difficulties].

Science.gov (United States)

Matoussi, N; Aissa, K; Fitouri, Z; Hajji, M; Makni, S; Bellagha, I; Ben Becher, S

2008-06-01

Central diabetes insipidus is rare in children. Characteristic features include polyuria and polydipsia due to arginine vasopressin deficiency. The differential diagnosis of polyuric states may be difficult. Etiologic diagnosis of central diabetes insipidus may be an equally difficult task. To specify the difficulties encountered in the diagnosis of central diabetes insipidus and to point out features of the etiologic work-up and of long-term follow-up of children with idiopathic central diabetes insipidus. A retrospective study of 12 children admitted with a polyuria/polydipsia syndrome to the pediatric - consultation and emergency unit of the children's hospital of Tunis between 1988 and 2005. Children with acquired nephrogenic central diabetes insipidus were excluded. Fourteen-hour fluid restriction test and/or desmopressin test were used without plasma vasopressin measurement. Eight patients were classified as having central diabetes insipidus, which was severe in seven children and partial in one girl. One patient was classified as having primary polydipsia. The diagnosis remains unclear in three patients. The etiological work-up in eight patients with central diabetes insipidus enabled the identification of Langerhan's-cell histiocytosis in two patients and neurosurgical trauma in one. The cause was considered idiopathic in five patients. The median follow-up of the five patients with idiopathic central diabetes insipidus was five years two months plus or minus six years seven months (range five months, 14.5 years). During this follow-up, neither brain magnetic resonance imaging scans findings nor anterior pituitary function have changed. Fluid restriction and desmopressin tests did not enable an accurate distinction between partial diabetes insipidus and primary polydipsia. Regular surveillance is warranted in patients with idiopathic central diabetes insipidus to identify potential etiologies.

Gangs in Central America

National Research Council Canada - National Science Library

Ribando, Clare

2005-01-01

... activities of Central American gangs. Citizens in several Central American countries have identified crime and gang violence among the top issues of popular concern, and Honduras and El Salvador have recently enacted tough anti-gang legislation...

Influence of arm movement on central tip location of peripherally inserted central catheters (PICCs)

International Nuclear Information System (INIS)

Connolly, Bairbre; Amaral, Joao; Walsh, Sharon; Temple, Michael; Chait, Peter; Stephens, Derek

2006-01-01

PICCs are increasingly employed in children. Some of their risks relate to the location of the central tip. Despite care when placing lines, they sometimes move. To evaluate the influence of arm movement on the central tip location of PICCs placed in children. The central tip location of PICCs was studied in 85 children, with the arm placed in six positions. The variables of side, vein, site and arm position were examined to measure the direction and range of tip movement. The side, site or vein used did not influence the range of movement of the central tip. Change in position of the arm had a significant influence on the central tip location, moving it an average of 2.2 rib spaces, a maximum of 3.5 ribs. Elbow bending and adduction of the arm caused the central tip to move deeper into the chest, compared to when the arm was straight and abducted 90 . Arm position is the significant variable influencing PICC movement. Side, site and vein do not influence the range of movement significantly. Most PICCs descend deeper into the chest with arm adduction and elbow bending. (orig.)

Central presbycusis: an emerging view.

Science.gov (United States)

Gates, George A

2012-07-01

Age-related dysfunction of the central auditory system (central presbycusis) is common but rarely looked for by those who provide aural rehabilitation. Patients who complain of difficulty hearing in noise--the key symptom of central presbycusis--are generally disadvantaged with conventional rehabilitation. This symptom should be documented with commercially available speech-in-noise tests, which use materials that are uncomplicated to administer. Those patients who perform poorly on such tests should have a customized rehabilitation program aimed at optimizing their remaining communication abilities. Otolaryngologists who provide auditory rehabilitation may wish to consider expanding their practices to meet the communication needs of older patients with central presbycusis. Central presbycusis is an emerging area for basic and clinical research in auditory neurotology, particularly in the relation of cognitive dysfunction to impaired auditory processing.

Central Diffraction in ALICE

CERN Document Server

Schicker, R

2012-01-01

The ALICE experiment at the Large Hadron Collider (LHC) at CERN consists of a central barrel, a muon spectrometer and of additional detectors for trigger and event classification purposes. The low transverse momentum threshold of the central barrel gives ALICE a unique opportunity to study the low mass sector of central production at the LHC. I will report on first analysis results of meson production in double gap events in minimum-bias proton-proton collisions at sqrt{s} = 7 TeV, and will describe a dedicated double gap trigger for future data taking.

Põlvkonnad baltisaksa ajalookirjutuses aastail 1919-2009 / Gert von Pistohlkors ; inglis- ja saksakeelsest käsikirjast tõlkinud Jaan Undusk

Index Scriptorium Estoniae

Pistohlkors, Gert von 1935-

2010-01-01

Baltisaksa ajaloolastest, kes avaldasid oma töid Baltimaade ajaloost ajavahemikul 1919-2009. Artikkel põhineb 4. detsembril 2009. aastal Södertörni Ülikoolis peetud konverentsil "East and central European history writing in exile - international dissemination of knowledge"

A new cascaded hydropower plants in El Sheikh Zayed Canal in the new valley in Egypt

Energy Technology Data Exchange (ETDEWEB)

Hosny Fahmy, Faten [Electronics Research Institute, Cairo (Egypt)

2000-07-01

industria, el transporte, las comunicaciones y los caminos, asi como servicios sociales salud y educacion, los cuales dirigiran a Egipto a los horizontes del siglo XXI. Estos nuevos proyectos son los de Toshka, Nuevo Valle o Nuevo Delta y Sheikh Zayed que alimentaran mas de un millon de almas, transformando el desierto en una alfombra verde, moviendo las ruedas de las industrias y despojandose de la pesadilla de muerte sobre un asfixiante valle estrecho. Este articulo presenta una nueva idea y aplicacion para saber utilizar el flujo del agua desde el lago Nasser despues de elevar y bombear a cierta velocidad de acuerdo al declive del suelo. Una serie de plantas hidroelectricas estan disenadas en ciertos puntos de interes en el Canal El Sheikh Zayed para generar energia electrica que se necesitara para alimentar varios proyectos en este nuevo valle. Los resultados muestran la comparacion entre estas ocho plantas hidroelectricas o sea: Su generacion electrica, su liberacion de agua por energia electrica generada, almacenamiento de agua y carga hidraulica de cada una. El estudio contiene tambien modelos matematicos de cada planta hidroelectrica y la descripcion matematica de cada embalse, represas y planta electrica.

Central control of body temperature.

Science.gov (United States)

Morrison, Shaun F

2016-01-01

Central neural circuits orchestrate the behavioral and autonomic repertoire that maintains body temperature during environmental temperature challenges and alters body temperature during the inflammatory response and behavioral states and in response to declining energy homeostasis. This review summarizes the central nervous system circuit mechanisms controlling the principal thermoeffectors for body temperature regulation: cutaneous vasoconstriction regulating heat loss and shivering and brown adipose tissue for thermogenesis. The activation of these thermoeffectors is regulated by parallel but distinct efferent pathways within the central nervous system that share a common peripheral thermal sensory input. The model for the neural circuit mechanism underlying central thermoregulatory control provides a useful platform for further understanding of the functional organization of central thermoregulation, for elucidating the hypothalamic circuitry and neurotransmitters involved in body temperature regulation, and for the discovery of novel therapeutic approaches to modulating body temperature and energy homeostasis.

A global central banker competency model

Directory of Open Access Journals (Sweden)

David W. Brits

2014-07-01

Full Text Available Orientation: No comprehensive, integrated competency model exists for central bankers. Due to the importance of central banks in the context of the ongoing global financial crisis, it was deemed necessary to design and validate such a model. Research purpose: To craft and validate a comprehensive, integrated global central banker competency model (GCBCM and to assess whether central banks using the GCBCM for training have a higher global influence. Motivation for the study: Limited consensus exists globally about what constitutes a ‘competent’ central banker. A quantitatively validated GCBCM would make a significant contribution to enhancing central banker effectiveness, and also provide a solid foundation for effective people management. Research approach, design and method: A blended quantitative and qualitative research approach was taken. Two sets of hypotheses were tested regarding the relationships between the GCBCM and the training offered, using the model on the one hand, and a central bank’s global influence on the other. Main findings: The GCBCM was generally accepted across all participating central banks globally, although some differences were found between central banks with higher and lower global influence. The actual training offered by central banks in terms of the model, however, is generally limited to technical-functional skills. The GCBCM is therefore at present predominantly aspirational. Significant differences were found regarding the training offered. Practical/managerial implications: By adopting the GCBCM, central banks would be able to develop organisation-specific competency models in order to enhance their organisational capabilities and play their increasingly important global role more effectively. Contribution: A generic conceptual framework for the crafting of a competency model with evaluation criteria was developed. A GCBCM was quantitatively validated.

Rapport over modelforsøg

DEFF Research Database (Denmark)

Burcharth, Hans F.; Frigaard, Peter

På foranledning af Monberg og Thorsen A/S (MT) ved ing. Carsten Bojsen og ing. Folmer Christensen er gennemført modelforsøg til vurdering af overskyl af den projekterede kystsikring foran Kattegatcenteret, som på forsøgstidspunktet var under udførelse.......På foranledning af Monberg og Thorsen A/S (MT) ved ing. Carsten Bojsen og ing. Folmer Christensen er gennemført modelforsøg til vurdering af overskyl af den projekterede kystsikring foran Kattegatcenteret, som på forsøgstidspunktet var under udførelse....

CENTRAL BANKING IN THE NEW ERA

Directory of Open Access Journals (Sweden)

Bilal Bagis

2017-12-01

Full Text Available This paper analyzes the evolution of central banking, and in particular the American experience of central banking. It provides projections for the future of central banking in the new era of post 2008. The paper initially demonstrates recent improvements in the financial and banking sectors, regulations and different measures of monetary and financial rules both in the USA and the rest of the advanced economies. Then, it claims institutions, such as central banks, will gain new objectives and more significance in this new era and thus will be given new roles, over time and along with the improvements and deepening in the financial system. The paper argues centuries long central bank evolution is not complete yet and that more objectives should be expected to come forward. In that line, there is need for a shift in the conventional policy measures. New trends in central banking such as the helicopter money, popular nominal GDP targeting regime and the retro developmental central banking are all critically analyzed. The paper provides a breakdown of financial development and central banking activities in a historical context and provides a rationale and a new basis for possible future innovations.

Actual versus perceived central bank transparency: the case of the European Central Bank

NARCIS (Netherlands)

van der Cruijsen, C.; Eijffinger, S.

2008-01-01

Central banks have become more and more transparent about their monetary policy making process. In the central bank transparency literature the distinction between actual and perceived transparency is often lacking. However, as perceptions are crucial for the actions of economic agents this

Optimal Central Bank Transparency

NARCIS (Netherlands)

van der Cruijsen, C.A.B.; Eijffinger, S.C.W.; Hoogduin, L.H.

2008-01-01

Should central banks increase their degree of transparency any further? We show that there is likely to be an optimal intermediate degree of central bank transparency. Up to this optimum more transparency is desirable: it improves the quality of private sector inflation forecasts. But beyond the

Optimal central bank transparency

NARCIS (Netherlands)

van der Cruijsen, C.A.B.; Eijffinger, S.C.W.; Hoogduin, L.

2008-01-01

Should central banks increase their degree of transparency any further? We show that there is likely to be an optimal intermediate degree of central bank transparency. Up to this optimum more transparency is desirable: it improves the quality of private sector inflation forecasts. But beyond the

Optimal central bank transparency

NARCIS (Netherlands)

van der Cruijsen, C.A.B.; Eijffinger, S.C.W.; Hoogduin, L.H.

2010-01-01

Should central banks increase their degree of transparency any further? We show that there is likely to be an optimal intermediate degree of central bank transparency. Up to this optimum more transparency is desirable: it improves the quality of private sector inflation forecasts. But beyond the

Approximating centrality in evolving graphs: toward sublinearity

Science.gov (United States)

Priest, Benjamin W.; Cybenko, George

2017-05-01

The identification of important nodes is a ubiquitous problem in the analysis of social networks. Centrality indices (such as degree centrality, closeness centrality, betweenness centrality, PageRank, and others) are used across many domains to accomplish this task. However, the computation of such indices is expensive on large graphs. Moreover, evolving graphs are becoming increasingly important in many applications. It is therefore desirable to develop on-line algorithms that can approximate centrality measures using memory sublinear in the size of the graph. We discuss the challenges facing the semi-streaming computation of many centrality indices. In particular, we apply recent advances in the streaming and sketching literature to provide a preliminary streaming approximation algorithm for degree centrality utilizing CountSketch and a multi-pass semi-streaming approximation algorithm for closeness centrality leveraging a spanner obtained through iteratively sketching the vertex-edge adjacency matrix. We also discuss possible ways forward for approximating betweenness centrality, as well as spectral measures of centrality. We provide a preliminary result using sketched low-rank approximations to approximate the output of the HITS algorithm.

Central venous pressure monitoring via peripherally or centrally inserted central catheters: a systematic review and meta-analysis.

Science.gov (United States)

Sanfilippo, Filippo; Noto, Alberto; Martucci, Gennaro; Farbo, Marco; Burgio, Gaetano; Biasucci, Daniele G

2017-07-14

The central venous pressure (CVP) is the most commonly used static marker of preload for guiding fluid therapy in critically ill patients, though its usefulness remains controversial. Centrally inserted central catheters (CICCs) are the gold-standard devices for CVP monitoring but peripherally inserted central catheters (PICCs) may represent a valid alternative. We undertook a systematic review and meta-analysis with the aim to investigate whether the difference between PICC- and CICC-measured CVP is not significant. We searched for clinical studies published in PubMed and EMBASE databases from inception until December 21st 2016. We included studies providing data on paired and simultaneous CVP measurement from PICCs and CICCs. We conducted two analyses on the values of CVP, the first one according to the total number of CVP assessments, the second one considering the number of patients recruited. Four studies matched the inclusion criteria, but only three of them provided data for the meta-analyses. Both analyses showed non-significant differences between PICC-measured and CICC-measured CVP: 1489 paired simultaneous CVP assessments (MD 0.16, 95%CI -0.14, 0.45, p = 0.30) on a total of 57 patients (MD 0.22, 95%CI -1.46, 1.91, p = 0.80). Both analyses showed no heterogeneity (I2 = 0%). Available evidence supports that CVP monitoring with PICCs is accurate and reproduces similar values to those obtained from CICCs. The possibility to monitor CVP should not be used among clinical criteria for preferring a CICC over a PICC line.

Controlling centrality in complex networks

Science.gov (United States)

Nicosia, V.; Criado, R.; Romance, M.; Russo, G.; Latora, V.

2012-01-01

Spectral centrality measures allow to identify influential individuals in social groups, to rank Web pages by popularity, and even to determine the impact of scientific researches. The centrality score of a node within a network crucially depends on the entire pattern of connections, so that the usual approach is to compute node centralities once the network structure is assigned. We face here with the inverse problem, that is, we study how to modify the centrality scores of the nodes by acting on the structure of a given network. We show that there exist particular subsets of nodes, called controlling sets, which can assign any prescribed set of centrality values to all the nodes of a graph, by cooperatively tuning the weights of their out-going links. We found that many large networks from the real world have surprisingly small controlling sets, containing even less than 5 – 10% of the nodes. PMID:22355732

"Miss"ing Me and "Ms"ing the Other: Courtesy Titles for Women in Englishes

Science.gov (United States)

Winter, Joanne; Pauwels, Anne

2007-01-01

The introduction and spread of "Ms" as the courtesy address title for women is a cornerstone of feminist linguistic planning for English. Its introduction aimed to eradicate the discriminatory inequity in the address system that exposed women through their (non)marital relationship with men. The understanding, use and impact of the courtesy title…

Les enjeux liés à l’intégration de l’approche BIM de modélisation des données du bâtiment à l’enseignement universitaire : cas d’une école d’ingénierie

Directory of Open Access Journals (Sweden)

Conrad Boton

2017-01-01

Full Text Available Le succès grandissant de l’approche de modélisation des données du bâtiment (BIM change le paradigme de fonctionnement de l’industrie de la construction et les universités sont confrontées à des défis importants dans leurs efforts pour introduire l’approche BIM dans l’enseignement. Plusieurs travaux ont étudié la question, mais chaque étude en a abordé des aspects spécifiques. Ainsi, il n’existe pas de cadre global fournissant des lignes directrices pratiques et neutres. Le cadre proposé dans cet article établit sept grands défis : les compétences à acquérir, l’approche pédagogique, les méthodes d’évaluation, l’environnement technologique, les partenariats industriels, l’approche de mise en œuvre et le calendrier. L’étude du cas d’une université d’ingénierie canadienne est également proposée.

EIGENVECTOR-BASED CENTRALITY MEASURES FOR TEMPORAL NETWORKS*

Science.gov (United States)

TAYLOR, DANE; MYERS, SEAN A.; CLAUSET, AARON; PORTER, MASON A.; MUCHA, PETER J.

2017-01-01

Numerous centrality measures have been developed to quantify the importances of nodes in time-independent networks, and many of them can be expressed as the leading eigenvector of some matrix. With the increasing availability of network data that changes in time, it is important to extend such eigenvector-based centrality measures to time-dependent networks. In this paper, we introduce a principled generalization of network centrality measures that is valid for any eigenvector-based centrality. We consider a temporal network with N nodes as a sequence of T layers that describe the network during different time windows, and we couple centrality matrices for the layers into a supra-centrality matrix of size NT × NT whose dominant eigenvector gives the centrality of each node i at each time t. We refer to this eigenvector and its components as a joint centrality, as it reflects the importances of both the node i and the time layer t. We also introduce the concepts of marginal and conditional centralities, which facilitate the study of centrality trajectories over time. We find that the strength of coupling between layers is important for determining multiscale properties of centrality, such as localization phenomena and the time scale of centrality changes. In the strong-coupling regime, we derive expressions for time-averaged centralities, which are given by the zeroth-order terms of a singular perturbation expansion. We also study first-order terms to obtain first-order-mover scores, which concisely describe the magnitude of nodes’ centrality changes over time. As examples, we apply our method to three empirical temporal networks: the United States Ph.D. exchange in mathematics, costarring relationships among top-billed actors during the Golden Age of Hollywood, and citations of decisions from the United States Supreme Court. PMID:29046619

Central gain control in tinnitus and hyperacusis

Directory of Open Access Journals (Sweden)

Benjamin D Auerbach

2014-10-01

Full Text Available Sensorineural hearing loss induced by noise or ototoxic drug exposure reduces the neural activity transmitted from the cochlea to the central auditory system. Despite a reduced cochlear output, neural activity from more central auditory structures is paradoxically enhanced at suprathreshold intensities. This compensatory increase in the central auditory activity in response to the loss of sensory input is referred to as central gain enhancement. Enhanced central gain is hypothesized to be a potential mechanism that gives rise to hyperacusis and tinnitus, two debilitating auditory perceptual disorders that afflict millions of individuals. This review will examine the evidence for gain enhancement in the central auditory system in response to cochlear damage. Further, it will address the potential cellular and molecular mechanisms underlying this enhancement and discuss the contribution of central gain enhancement to tinnitus and hyperacusis. Current evidence suggests that multiple mechanisms with distinct temporal and spectral profiles are likely to contribute to central gain enhancement. Dissecting the contributions of these different mechanisms at different levels of the central auditory system is essential for elucidating the role of central gain enhancement in tinnitus and hyperacusis and, most importantly, the development of novel treatments for these disorders.

Central Gain Control in Tinnitus and Hyperacusis

Science.gov (United States)

Auerbach, Benjamin D.; Rodrigues, Paulo V.; Salvi, Richard J.

2014-01-01

Sensorineural hearing loss induced by noise or ototoxic drug exposure reduces the neural activity transmitted from the cochlea to the central auditory system. Despite a reduced cochlear output, neural activity from more central auditory structures is paradoxically enhanced at suprathreshold intensities. This compensatory increase in the central auditory activity in response to the loss of sensory input is referred to as central gain enhancement. Enhanced central gain is hypothesized to be a potential mechanism that gives rise to hyperacusis and tinnitus, two debilitating auditory perceptual disorders that afflict millions of individuals. This review will examine the evidence for gain enhancement in the central auditory system in response to cochlear damage. Further, it will address the potential cellular and molecular mechanisms underlying this enhancement and discuss the contribution of central gain enhancement to tinnitus and hyperacusis. Current evidence suggests that multiple mechanisms with distinct temporal and spectral profiles are likely to contribute to central gain enhancement. Dissecting the contributions of these different mechanisms at different levels of the central auditory system is essential for elucidating the role of central gain enhancement in tinnitus and hyperacusis and, most importantly, the development of novel treatments for these disorders. PMID:25386157

Granuloma central de células gigantes Giant cells central granuloma

Directory of Open Access Journals (Sweden)

Ayelén María Portelles Massó

2011-03-01

Full Text Available El granuloma reparativo central de células gigantes es una lesión proliferativa no neoplásica de etiología desconocida. Se presenta un paciente masculino de 40 años de edad, portador de prótesis parcial superior. Fue remitido al Servicio de Cirugía Maxilofacial del Hospital "V. I. Lenin" por presentar aumento de volumen en reborde alveolar superior, de color rojo grisáceo y que provocaba expansión de corticales óseas. Una vez analizados los exámenes clínicos, radiográficos e histopatológicos se diagnosticó un granuloma reparativo central de células gigantes Se realizó exéresis quirúrgica de la lesión y extracción de dientes adyacentes con una evolución satisfactoria sin señales de recidivas luego de tres años del tratamiento. El granuloma reparativo central de células gigantes se presentó como respuesta a un trauma. La correcta interpretación de los datos clínicos, radiográficos e histopatológicos nos permitió llegar al correcto diagnóstico y plan de tratamiento.Giant-cell central reparative granuloma is non neoplastic proliferative lesion of unknown etiology. We report a 40 years old male patient who was admitted at the Maxillofacial Service of the "V. I. Lenin" Hospital. The patient had partial upper prosthesis and was complaining of red-grey volume increase lesion in upper alveolar ridge which led to the expansion of cortical bone. Having analyzed clinical, radiographic and histopathological findings the case was concluded as a giant-cell central reparative granuloma. Surgical exeresis and adjunct tooth extraction were done. After three years of treatment, satisfactory follow up without recurrence is reported.

AAPT Diagnostic Criteria for Central Neuropathic Pain

DEFF Research Database (Denmark)

Widerstrom-Noga, Eva; Loeser, John D.; Jensen, Troels Staehelin

2017-01-01

Central neuropathic pain, which is pain caused by a lesion or disease of the central somatosensory nervous system, is a serious consequence of spinal cord injury, stroke, multiple sclerosis, and other conditions affecting the central nervous system. A collaborative effort between the Analgesic....... This article focuses on central neuropathic pain associated with spinal cord injury, stroke, and multiple sclerosis, but the AAPT framework can be extended to central pain due to other causes such as traumatic brain injury. The classification of central neuropathic pain is organized according to the AAPT...

Idiopathic central diabetes Insipidus.

Science.gov (United States)

Grace, Mary; Balachandran, Venu; Menon, Sooraj

2011-10-01

Idiopathic central diabetes insipidus (CDI) is a rare disorder characterized clinically by polyuria and polydipsia, and an abnormal urinary concentration without any identified etiology. We report a case of central diabetes insipidus in a 60-year-old lady in the absence of secondary causes like trauma, infection, and infiltrative disorders of brain.

Central Diabetes Insipidus, Central Hypothyroidism, Renal Tubular ...

African Journals Online (AJOL)

readmitted to the hospital because of jaundice and failure to thrive, for which he was investigated and diagnosed to have central congenital hypothyroidism. Shortly thereafter, he was admitted to our institute with a history of vomiting, decreased oral intake, polyuria, and dehydration having lasted 5 days. He was investigated ...

Central bank independence and inflation revisited

NARCIS (Netherlands)

Klomp, Jeroen; de Haan, Jakob

We re-examine the relationship between central bank independence (CBI), proxied by the central bank governor's turnover rate and an indicator based on central bank laws in place, and inflation using a random coefficient model with the Hildreth-Houck estimator for more than 100 countries in the

Central bank independence and inflation revisited

NARCIS (Netherlands)

Klomp, J.G.; Haan, de J.

2010-01-01

We re-examine the relationship between central bank independence (CBI), proxied by the central bank governor's turnover rate and an indicator based on central bank laws in place, and inflation using a random coefficient model with the Hildreth-Houck estimator for more than 100 countries in the

Performance contracting in central government in Denmark

DEFF Research Database (Denmark)

Kristiansen, Mads Bøge

2015-01-01

) are observed across central government agencies, when the content of the performance contracts is compared. This makes it interesting to examine how variation in the content of the performance contracts across agencies can be explained? Based on a broad theoretical framework in which variation......This paper looks into performance contracting in Danish central government. Management by Objectives and Results (MBOR) was adopted in central government in Denmark during the 1980s and early 1990s. In 1991, performance contracts between parent ministries and their agencies were introduced...... in Danish central government. Since their introduction, performance contracts have become central elements in the steering and management of agencies in central government in Denmark, and today they are nearly universally adopted in central government. In Denmark, the Ministry of Finance is responsible...

Central Bank independence

Directory of Open Access Journals (Sweden)

Vasile DEDU

2012-08-01

Full Text Available In this paper we present the key aspects regarding central bank’s independence. Most economists consider that the factor which positively influences the efficiency of monetary policy measures is the high independence of the central bank. We determined that the National Bank of Romania (NBR has a high degree of independence. NBR has both goal and instrument independence. We also consider that the hike of NBR’s independence played an important role in the significant disinflation process, as headline inflation dropped inside the targeted band of 3% ± 1 percentage point recently.

Central Venous Access

International Nuclear Information System (INIS)

Ganeshan, Arul; Warakaulle, Dinuke R.; Uberoi, Raman

2007-01-01

Central venous access plays an important role in the management of an ever-increasing population of patients ranging from those that are critically ill to patients with difficult clinical access. Interventional radiologists are key in delivering this service and should be familiar with the wide range of techniques and catheters now available to them. A comprehensive description of these catheters with regard to indications, technical aspects of catheterization, success rates, and associated early and late complications, as well as a review of various published guidelines on central venous catheter insertion are given in this article

Risk Premium and Central Bank Intervention

OpenAIRE

Pinar Ozlu

2006-01-01

This study examines the relation between the risk premium and central bank intervention. Forward rates are calculated for the Turkish Lira-USD exchange market and then the effect of central bank intervention on the risk premium is estimated. Using high quality daily intervention data from the Central Bank of Turkey as well as implied forward rates, an MA (21)-GARCH (1,1) model is estimated. Both purchases and sales of US dollars by the Central Bank of Turkey appear to have no effect on the si...

OGLE-ing the Magellanic system: stellar populations in the Magellanic Bridge

International Nuclear Information System (INIS)

Skowron, D. M.; Jacyszyn, A. M.; Udalski, A.; Szymański, M. K.; Skowron, J.; Poleski, R.; Kozłowski, S.; Kubiak, M.; Pietrzyński, G.; Soszyński, I.; Mróz, P.; Pietrukowicz, P.; Ulaczyk, K.; Wyrzykowski, Ł.

2014-01-01

We report the discovery of a young stellar bridge that forms a continuous connection between the Magellanic Clouds. This finding is based on number density maps for stellar populations found in data gathered by OGLE-IV that fully cover over 270 deg 2 of the sky in the Magellanic Bridge area. This is the most extensive optical survey of this region to date. We find that the young population is present mainly in the western half of the MBR, which, together with the newly discovered young population in the eastern Bridge, form a continuous stream of stars connecting both galaxies along δ ∼ –73.5 deg. The young population distribution is clumped, with one of the major densities close to the SMC and the other fairly isolated and located approximately mid-way between the Clouds, which we call the OGLE island. These overdensities are well matched by H I surface density contours, although the newly found young population in the eastern Bridge is offset by ∼2 deg north from the highest H I density contour. We observe a continuity of red clump stars between the Magellanic Clouds which represent an intermediate-age population. Red clump stars are present mainly in the southern and central parts of the Magellanic Bridge, below its gaseous part, and their presence is reflected by a strong deviation from the radial density profiles of the two galaxies. This may indicate either a tidal stream of stars, or that the stellar halos of the two galaxies overlap. On the other hand, we do not observe such an overlap within an intermediate-age population represented by the top of the red giant branch and the asymptotic giant branch stars. We also see only minor mixing of the old populations of the Clouds in the southern part of the Bridge, represented by the lowest part of the red giant branch.

OGLE-ing the Magellanic system: stellar populations in the Magellanic Bridge

Energy Technology Data Exchange (ETDEWEB)

Skowron, D. M.; Jacyszyn, A. M.; Udalski, A.; Szymański, M. K.; Skowron, J.; Poleski, R.; Kozłowski, S.; Kubiak, M.; Pietrzyński, G.; Soszyński, I.; Mróz, P.; Pietrukowicz, P.; Ulaczyk, K.; Wyrzykowski, Ł., E-mail: dszczyg@astrouw.edu.pl [Warsaw University Astronomical Observatory, Aleje Ujazdowskie 4, 00-478 Warszawa (Poland)

2014-11-10

We report the discovery of a young stellar bridge that forms a continuous connection between the Magellanic Clouds. This finding is based on number density maps for stellar populations found in data gathered by OGLE-IV that fully cover over 270 deg{sup 2} of the sky in the Magellanic Bridge area. This is the most extensive optical survey of this region to date. We find that the young population is present mainly in the western half of the MBR, which, together with the newly discovered young population in the eastern Bridge, form a continuous stream of stars connecting both galaxies along δ ∼ –73.5 deg. The young population distribution is clumped, with one of the major densities close to the SMC and the other fairly isolated and located approximately mid-way between the Clouds, which we call the OGLE island. These overdensities are well matched by H I surface density contours, although the newly found young population in the eastern Bridge is offset by ∼2 deg north from the highest H I density contour. We observe a continuity of red clump stars between the Magellanic Clouds which represent an intermediate-age population. Red clump stars are present mainly in the southern and central parts of the Magellanic Bridge, below its gaseous part, and their presence is reflected by a strong deviation from the radial density profiles of the two galaxies. This may indicate either a tidal stream of stars, or that the stellar halos of the two galaxies overlap. On the other hand, we do not observe such an overlap within an intermediate-age population represented by the top of the red giant branch and the asymptotic giant branch stars. We also see only minor mixing of the old populations of the Clouds in the southern part of the Bridge, represented by the lowest part of the red giant branch.

Big Data and central banks

OpenAIRE

David Bholat

2015-01-01

This commentary recaps a Centre for Central Banking Studies event held at the Bank of England on 2–3 July 2014. The article covers three main points. First, it situates the Centre for Central Banking Studies event within the context of the Bank’s Strategic Plan and initiatives. Second, it summarises and reflects on major themes from the event. Third, the article links central banks’ emerging interest in Big Data approaches with their broader uptake by other economic agents.

Big Data and central banks

Directory of Open Access Journals (Sweden)

David Bholat

2015-04-01

Full Text Available This commentary recaps a Centre for Central Banking Studies event held at the Bank of England on 2–3 July 2014. The article covers three main points. First, it situates the Centre for Central Banking Studies event within the context of the Bank’s Strategic Plan and initiatives. Second, it summarises and reflects on major themes from the event. Third, the article links central banks’ emerging interest in Big Data approaches with their broader uptake by other economic agents.

Central Bank Independence, Centralization of Wage Bargaining, Inflation and Unemployment - Theory and Some Evidence

NARCIS (Netherlands)

Cukierman, A.; Lippi, F.

1998-01-01

This paper proposes a conceptual framework to investigate the effects of central bank independence, of the degree of centralization of wage bargaining and of the interaction between those institutional variables, on real wages, unemployment and inflation, in a framework in which unions are averse to

Central Asia's raging waters the prospects of water conflict in Central Asia

OpenAIRE

Hartman, William B.

2007-01-01

This thesis examines the prospects of conflict caused by water scarcity in Central Asia. The thesis analyzes the three most recent political eras of Central Asia, Tsarist Russia, the Soviet Union and independence, utilizing indicators of water tensions including: water quality, water quantity, the management of water for multiple uses, the political divisions and geopolitical setting, state institutions and national water ethos. Although water is not likely to be the sole cause of a majo...

Central blood pressure and chronic kidney disease

Science.gov (United States)

Ohno, Yoichi; Kanno, Yoshihiko; Takenaka, Tsuneo

2016-01-01

In this review, we focused on the relationship between central blood pressure and chronic kidney diseases (CKD). Wave reflection is a major mechanism that determines central blood pressure in patients with CKD. Recent medical technology advances have enabled non-invasive central blood pressure measurements. Clinical trials have demonstrated that compared with brachial blood pressure, central blood pressure is a stronger risk factor for cardiovascular (CV) and renal diseases. CKD is characterized by a diminished renal autoregulatory ability, an augmented direct transmission of systemic blood pressure to glomeruli, and an increase in proteinuria. Any elevation in central blood pressure accelerates CKD progression. In the kidney, interstitial inflammation induces oxidative stress to handle proteinuria. Oxidative stress facilitates atherogenesis, increases arterial stiffness and central blood pressure, and worsens the CV prognosis in patients with CKD. A vicious cycle exists between CKD and central blood pressure. To stop this cycle, vasodilator antihypertensive drugs and statins can reduce central blood pressure and oxidative stress. Even in early-stage CKD, mineral and bone disorders (MBD) may develop. MBD promotes oxidative stress, arteriosclerosis, and elevated central blood pressure in patients with CKD. Early intervention or prevention seems necessary to maintain vascular health in patients with CKD. PMID:26788468

Payments and Central Bank Policy

DEFF Research Database (Denmark)

Korsgaard, Søren

This thesis consists of three chapters. The rst, "Paying for Payments", examines the role of interchange fees in payment card networks. The second, "Bank Liquidity and the Interbank Market" (co-authored with Mikael Reimer Jensen), investigates how banks' liquidity holdings at the central bank a ect...... outcomes in the money market. The third, "Collateralized Lending and Central Bank Collateral Policy", considers the emergence of credit constraints under collateralized lending, and how central banks use collateral policy to mitigate these constraints. While the chapters can be read independently......, they share common themes. Each chapter is concerned with payments in one way or another, each is concerned with the e ciency of market outcomes, and, to the extent that there is scope for improving these outcomes, each discusses the appropriate role for policy, in particular central bank policy....

Assessment of the turbine trip transient in Cofrentes NPP with TRAC-BF1

International Nuclear Information System (INIS)

Castrillo, F.; Gomez, A.; Gallego, I.

1993-06-01

This report presents the results of the assessment of TRAC-BF1 (G1-J1) code with the model of C. N. Cofrentes for simulation of the transient originated by the manual trip of the main turbine. C. N. Cofrentes is a General Electric designed BWR/6 plant, with a nominal core thermal power of 2894 Mwt, in commercial operation since 1985, owned and operated by Hidroelectrica Espanola, S. A. The plant incorporates all the characteristics of BWR/6 reactors, with two turbine driven FW pumps. As a result of this assessment a model of C. N. Cofrentes has been developed for TRAC-BF1 that fairly reproduces operational transient behavior of the plant. A special purpose code was generated to obtain reactivity coefficients, as required by TRAC-BF1, from the 3D simulator

Do central bank law reforms affect the term in office of central bank governors?

NARCIS (Netherlands)

Klomp, J.G.; de Haan, J.

In this paper we confirm the hypothesis that central bank independence reforms reduce the likelihood that a central bank governor will be replaced. However, the strength of this effect depends on the rule of law and the degree of political polarization. (c) 2009 Elsevier B.V. All rights reserved.

Current status of laparoscopic central pancreatectomy

Directory of Open Access Journals (Sweden)

CAO Yang

2017-04-01

Full Text Available Central pancreatectomy is an ideal surgical procedure for the treatment of benign or low-grade malignant tumors in the pancreatic neck or the proximal body of the pancreas, and it can preserve more normal pancreatic tissue in order to reduce the incidence of endocrine and exocrine insufficiency after surgery. Although some clinical studies have demonstrated the feasibility and safety of this procedure, laparoscopic central pancreatectomy was technically challenging with a few number of cases. This article reviews the current status of laparoscopic central pancreatectomy and introduces our clinical experience of laparoscopic central pancreatectomy and pancreaticojejunostomy.

Central cell confinement in MFTF-B

International Nuclear Information System (INIS)

Jong, R.A.

1981-01-01

The point code TANDEM has been used to survey the range of plasma parameters which can be attained in MFTF-B. The code solves for the electron and ion densities and temperatures in the central cell, yin-yang, barrier, and A-cell regions as well as the plasma potential in each region. In these studies, the A-cell sloshing ion beams were fixed while the neutral beams in the yin-yang and central cell, the gas feed in the central cell, and the applied ECRH power β, central cell ion density and temperature, and the confining potential are discussed

Central Hypothyroidism in Miniature Schnauzers

NARCIS (Netherlands)

Voorbij, Annemarie M W Y; Leegwater, Peter A J; Buijtels, Jenny J C W M; Daminet, Sylvie; Kooistra, Hans S

2016-01-01

BACKGROUND: Primary hypothyroidism is a common endocrinopathy in dogs. In contrast, central hypothyroidism is rare in this species. OBJECTIVES: The objective of this article is to describe the occurrence and clinical presentation of central hypothyroidism in Miniature Schnauzers. Additionally, the

Evaluation of Resource Utilization and Treatment Patterns in Patients with Actinic Keratosis in the United States.

Science.gov (United States)

Asche, Carl V; Zografos, Panagiotis; Norlin, Jenny M; Urbanek, Bill; Mamay, Carl; Makin, Charles; Erntoft, Sandra; Chen, Chi-Chang; Hines, Dionne M; Mark Siegel, Daniel

2016-01-01

To compare health care resource utilization and treatment patterns between patients with actinic keratosis (AK) treated with ingenol mebutate gel (IngMeb) and those treated with other field-directed AK therapies. A retrospective, propensity-score-matched, cohort study compared refill/repeat and adding-on/switching patterns and outpatient visits and prescriptions (health care resource utilization) over 6 months in patients receiving IngMeb versus those receiving imiquimod, 5-fluorouracil, diclofenac sodium, and methyl aminolevulinate or aminolevulinic acid photodynamic therapy (MAL/ALA-PDT). The final sample analyzed included four matched treatment cohort pairs (IngMeb and comparator; n = 790-971 per treatment arm). Refill rates were similar except for imiquimod (15% vs. 9% for imiquimod and IngMeb, respectively; P < 0.05). MAL/ALA-PDT treatment repetition rates were higher than IngMeb refill rates (20% vs. 10%; P < 0.05). Topical agent add-on/switch rates were comparable. PDT had higher switch rates than did IngMeb (5% vs. 2%; P < 0.05). The IngMeb cohort had a significantly lower proportion of patients with at least one AK-related outpatient visit during the 6-month follow-up than did any other cohort: versus imiquimod (50% vs. 66%; P < 0.0001), versus 5-fluorouracil (50% vs. 69%; P < 0.0001), versus diclofenac sodium (51% vs. 56%; P = 0.034), and versus MAL/ALA-PDT (50% vs. 100%; P < 0.0001). There were significantly fewer AK-related prescriptions among patients receiving IngMeb than among patients in other cohorts. Results based on the first 6 months after treatment initiation suggested that most field-directed AK therapies had clinically comparable treatment patterns except imiquimod, which was associated with higher refill rates, and PDT, which was associated with significantly more frequent treatment sessions and higher switching rates. IngMeb was also associated with significantly fewer outpatient visits than were other field-directed therapies. Copyright �

Ühiskonnakriitika kinos / Inge Pitsner

Index Scriptorium Estoniae

Pitsner, Inge

2004-01-01

Baltimaade dokfilmiprogramm "Subjektiivne kaamera", mis tutvustab uuemaid provokatiivseid, poleemikat tekitavaid autorikeskseid filme. See on osa Tallinnas toimuvast 8. Läänemere Dokumentalistika Foorumist

Viini noored arhitektid / Inge Laurik

Index Scriptorium Estoniae

Laurik, Inge

2001-01-01

21. augustist Pärnu Muuseumi Aidas Viini noori arhitekte tutvustav näitus "innere szene wien". Näha saab 47 Viini arhitektuuribüroo koostatud prospekte, olustikufotosid ateljeede töökeskkonnast, videoklippi.

Lnc-ing inflammation to disease

CSIR Research Space (South Africa)

Magagula, L

2017-08-01

Full Text Available by RNAi more than by antisense oligonucleotides. Nucleic Acids Res. 44, 863–877 doi:10.1093/nar/gkv1206 75 Zhen, S., Hua, L., Liu, Y.-H., Sun, X.-M., Jiang, M.-M., Chen, W. et al. (2017) Inhibition of long non-coding RNA UCA1 by CRISPR/Cas9 attenuated...

Complications of central venous stenosis due to permanent central venous catheters in children on hemodialysis.

Science.gov (United States)

Rinat, Choni; Ben-Shalom, Efrat; Becker-Cohen, Rachel; Feinstein, Sofia; Frishberg, Yaacov

2014-11-01

Central venous catheters are frequently used as access for hemodialysis (HD) in children. One of the known complications is central venous stenosis. Although this complication is not rare, it is often asymptomatic and therefore unacknowledged. Superior vena cava (SVC) stenosis is obviously suspected in the presence of upper body edema, but several other signs and symptoms are often unrecognized as being part of this syndrome. We describe four patients with various manifestations of central venous stenosis and SVC syndrome. These sometimes life- or organ-threatening conditions include obstructive sleep apnea, unresolving stridor, increased intracranial pressure, increased intraocular pressure, right-sided pleural effusion, protein-losing enteropathy and lymphadenopathy. The temporal relationship of these complications associated with the use of central venous catheters and documentation of venous stenosis, together with their resolution after alleviation of high venous pressure, points to a causal role. We suggest pathophysiological mechanisms for the formation of each of these complications. In patients with occlusion of the SVC, various unexpected clinical entities can be caused by high central venous pressure. As often the etiology is not obvious, a high index of suspicion is needed as in some cases prompt alleviation of the high pressure is mandatory.

Hydrology and water quality of Park Lake, south-central Wisconsin

Science.gov (United States)

Kammerer, P.A.

1996-01-01

Park Lake extends to the northeast from the village of Pardeeville in Columbia County (fig. 1). Local residents perceive water-quality problems in the lake that include excessive algae and aquatic plant growth. Algae and plant growth in a lake are controlled, in part, by the availability of phosphorus in the water. However, no measurements of phosphorus enter- ing the lake or of other factors that affect lake-water quality had been made, and available data on water quality were limited to 2 years of measurements at one site in the lake in 1986- 87. To obtain the data and in- formation needed to address the water-quality problems at Park Lake and to develop a management plan that would limit the input of phosphorus to the lake, the U.S. Geologi- cal Survey, in cooperation with the Park Lake Management District, studied the hydrology of the lake and collected data needed to determine sources and amount of phosphorus en- tering the lake. This Fact Sheet summarizes the results of that study. Data collected during the study were published in a separate report (Holmstrom and others, 1994, p. 70-85).

Model(ing) Law: The ICTY, the International Criminal Justice Template, and Reconciliation in the Former Yugoslavia

DEFF Research Database (Denmark)

Carlson, Kerstin Bree

2013-01-01

My project uses the case study of the ICTY and reconciliation in the Balkans to address the larger topic of the capacity of international criminal tribunals (ICTs) as transitional justice mechanisms. I argue that the ICTY operates under the (flawed) received wisdom of the IMT at Nuremberg, what I...... term the international criminal justice template. This template accords three transitional justice functions for ICTs beyond (and in conjunction with) their central judicial aim of adjudicating cases: as (1) articulators of progressive criminal law (2) historians and (3) reconcilers or storytellers. My...... and the development of international law and society studies, in order to better theorize and understand the structural and theoretical constraints governing the establishment of legitimacy for international criminal courts....

Accountability of central banks: aspects and quantification

Directory of Open Access Journals (Sweden)

J. DE HAAN

1999-06-01

Full Text Available The work examines the relationship between central bank independence and accountability. The authors do this by using an indicator for central bank accountability based on the laws of 16 central banks. Central bank accountability is identified as having three distinct features, namely, the explicit definition and ranking of the objectives of monetary policy, the transparency of the actual monetary policy, and the final responsibility to monetary policy.

Colloquium on Central Asia

International Nuclear Information System (INIS)

2005-01-01

This colloquium on Azerbaijan was organized by the direction of international relations of the French Senate and the French center of foreign trade (CFCE). This document gathers the interventions of the participants and the debates with the audience following these interventions. The topics treated concern: - the present day political-economical situation of Central Asia countries (problem of borders, relations with Russia and China); - the economies of Central Asia countries: short term problems and medium-term perspectives; - the relations with the European Union (political, economical, trade and investments, perspectives); - the European energy stakes of Caspian sea (oil and gas reserves, development of hydrocarbon resources, exploitation and transport constraints, stakes for Europe and France); - TotalFinaElf company in Central Asia (Kazakhstan, Azerbaijan, enclavement problem); - the economical impacts of the TRACECA pathway (Transport Corridor Europe Caucasus Asia). (J.S.)

The Naive Central Banker

Directory of Open Access Journals (Sweden)

Marcelo de Carvalho Griebeler

2015-09-01

Full Text Available There has been in some countries a trend of assigning other functions to central banks besides price stability. The most suggested function to be added to monetary authority’s obligations is to pursue economic growth or full employment. In this paper we characterize the behavior and analyse the optimal monetary policy of, what we call, a naive central banker. We describe the naive behavior as one that does face the inflation-unemployment trade-off, but it tries to minimize both variables simultaneously. Our findings, both under discretion and commitment, indicate that the naive central banker delivers lower expected inflation and inflation variance than the benchmark behavior whenever the economy is rigid enough. However, the degree of conservativeness also affects this result, such that the less conservative the naive policymaker, the more rigidity is necessary.

The central nervous system

International Nuclear Information System (INIS)

Holmes, R.A.

1984-01-01

The first section presents a comprehensive evaluation of radionuclide imaging of the central nervous system and provides a comparison of the detection accuracies of radionuclide imaging (RNI) and XCT in certain lesions, realizing that the XCT results may vary when radiocontrast or newer generation XCT scanners are used. Although conventional radionuclide imaging of the central nervous system has experienced no significant changes over the last 7 years except for mild refinements, a new section has been added on positron emission tomography (PET). Most positron radiopharmaceuticals passively cross the intact blood-brain barrier, and their localization has catalyzed renewed interest in our ability to metabolically study and obtain images of the central nervous system. The section on radionuclide cisternography has been rewritten to reflect present day practice and the wider application of XCT in describing conditions affecting the ventricular system

Report of the Central Tracking Group

International Nuclear Information System (INIS)

Cassel, D.G.; Hanson, G.G.

1986-10-01

Issues involved in building a realistic central tracking system for a general-purpose 4π detector for the SSC are addressed. Such a central tracking system must be capable of running at the full design luminosity of 10 33 cm -2 s -1 . Momentum measurement was required in a general-purpose 4π detector. Limitations on charged particle tracking detectors at the SSC imposed by rates and radiation damage are reviewed. Cell occupancy is the dominant constraint, which led us to the conclusion that only small cells, either wires or straw tubes, are suitable for a central tracking system at the SSC. Mechanical problems involved in building a central tracking system of either wires or straw tubes were studied, and our conclusion was that it is possible to build such a large central tracking system. Of course, a great deal of research and development is required. We also considered central tracking systems made of scintillating fibers or silicon microstrips, but our conclusion was that neither is a realistic candidate given the current state of technology. We began to work on computer simulation of a realistic central tracking system. Events from interesting physics processes at the SSC will be complex and will be further complicated by hits from out-of-time bunch crossings and multiple interactions within the same bunch crossing. Detailed computer simulations are needed to demonstrate that the pattern recognition and tracking problems can be solved

Centralized mouse repositories.

Science.gov (United States)

Donahue, Leah Rae; Hrabe de Angelis, Martin; Hagn, Michael; Franklin, Craig; Lloyd, K C Kent; Magnuson, Terry; McKerlie, Colin; Nakagata, Naomi; Obata, Yuichi; Read, Stuart; Wurst, Wolfgang; Hörlein, Andreas; Davisson, Muriel T

2012-10-01

Because the mouse is used so widely for biomedical research and the number of mouse models being generated is increasing rapidly, centralized repositories are essential if the valuable mouse strains and models that have been developed are to be securely preserved and fully exploited. Ensuring the ongoing availability of these mouse strains preserves the investment made in creating and characterizing them and creates a global resource of enormous value. The establishment of centralized mouse repositories around the world for distributing and archiving these resources has provided critical access to and preservation of these strains. This article describes the common and specialized activities provided by major mouse repositories around the world.

f Mo fingerl ortality ings in ch asses n varyi hanges ssment ing sal s ...

African Journals Online (AJOL)

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bioma lead. (Bhup. 410805622606 ccess under the ournal of E reochro and inf oxicity. - Allah Kaf of Lagos, P.M. 10 November, 2 d protection nce of salinit nce and rela nst O. niloti t chemical. C ls of 2, 12, 1 by Probit. Mo. 35 ppt within there was a s imilarly, the significance o confer pr ence on t icochemical ls and pest.

CreatIng Web-based Math learnIng tool for TURKISH mIddle school students: Webquest

Directory of Open Access Journals (Sweden)

Aytac KURTULUS

2009-04-01

Full Text Available Internet is the most important product for the computer technology and it began to be used in many fields. Especially in the recent years, the usage of Internet has increased in the fields of communication, entertainment, advertisement, media, and technology. In Turkey, the usage of Internet is not used very common and active in primary and secondary education. The fast developments of the new technologies and the Web-Based Education Systems must be increased the importance of giving courses. In this study, the information to be aimed at is to introduce the WebQuest system, which was developed at San Diego State University by Bernie Dodge. A webQuest can be used web-based math learning tool for Turkish middle school students. Therefore, an example of geometry education WebQuest is given to introduce WebQuest system because WebQuest will be active in geometry teaching similar to the other subjects. An overview of WebQuest technology application and several resources for teachers and students interested in creating WebQuests can be found on The WebQutest Page (Dodge, 2001. Table 1 lists web sites that have many of these resources.

DRAWING MUSIC! ANAL Y Z ING AN EXTRACURRICULAR ACTIVITY OF VISUALI Z ING A CONCERT

Directory of Open Access Journals (Sweden)

Váradi, Judit

2018-01-01

Full Text Available According to the literature and recent studies, a high number of encounters with classical music during childhood and adolescence in the context of positive feelings closely correlates with the formation of classical music competencies. During the investigation of primary students’ attitudes towards classical music, it has been revealed that those who have more opportunities to enter music education will come closer to understanding classical music. At the University of Debrecen Faculty of Music, we have organised and staged various educational youth performances in the last decades. Our goal is to get elementary school children acquainted with live music, classical instruments. A key element of our mission is to form the preferences of children and young people who do not participate in art education, so that they may become interested and sophisticated adults. In our paper we analysis the creations of the drawing competition what connects in theme with the youth concert.

Building the foundations for a new central bank doctrine: Redefining central banks’ missions in the 21st century

Directory of Open Access Journals (Sweden)

Eric Pichet

2013-05-01

Full Text Available The 2007-2008 financial crisis demonstrated both the responsibilities that central bankers, alongside other actors, bear for turbulences of this kind as well as how economics can be used to provide central bankers and governments with the understanding and tools that they need to prevent the international financial system from collapsing. At the same time, central banks’ responses to the crisis have taken monetary policy into unknown territory. The paper’s first section diagnoses good and bad practice in post-crisis central banking; assesses the efficiency of pre-crisis doctrines; and identifies the dangers of actions exceeding certain limits. It specifically focuses on the European Central Bank’s much-debated intervention in certain peripheral bond markets, particularly Greece. The second section is more normative and lays the foundations for a social science perspective of how to manage modern central banks, an approach that draws on a variety of disciplines including economics, governance theory and management. This starts with a definition of the new doctrine and its underlying philosophy, followed by an identification of sound central banking practices (revolving around a few key concepts, notably inflation and financial stability. The missions and objectives of these practices are then defined (along with a choice of indicators, culminating in an exploration of which strategies and tools might be used in both normal and turbulent times. Lastly, a few concrete rules of governance are offered, built on the triptych of central banks’ independence, accountability and composition, with specific focus placed on the process for selecting governors fit to handle the new role that modern central banks are destined to assume in developed countries.

Central Bank independence in Latin America La independencia de la Banca Central en América Latina

Directory of Open Access Journals (Sweden)

Junguito Bonnet Roberto

1996-06-01

Full Text Available This article describes the origin and evolution of the central banks of Argentina, Brazil, Chile, Colombia, Mexico, and Venezuela, and analyzes their respective institutional structures. It also studies the contribution of the central bank to stabilization and the problems for maintaining this independence into the future.Este artículo describe el origen y la evolución de los Bancos Centrales de Argentina, Brasil, Chile, Colombia, México y Venezuela, y analiza sus respectivas estructruras institucionales. También estudia la contribución de la banca central a la estabilización y los problemas para que esta independencia se mantenga en el futuro.

The European Central Bank and the Eurosystem

OpenAIRE

Carol C. Bertaut

2002-01-01

The Eurosystem comprises the European Central Bank at its center as well as the national central banks of the twelve countries currently participating in monetary union. The European Central Bank was established in July 1998, six months before the beginning of Stage Three of economic and monetary union. Although decisions regarding monetary policy are made centrally by the Governing Council of the Eurosystem, the operational aspects of monetary policy-including open market operations, adminis...

Incidence of thrombosis in children with tunneled central venous access devices versus peripherally inserted central catheters (PICCs).

Science.gov (United States)

Kanin, Maralee; Young, Guy

2013-11-01

The recent proliferation of deep vein thrombosis in children has been attributed to the increased use of central venous catheters, specifically tunneled lines and peripherally inserted central catheters. A formal comparison of the incidence rate for deep vein thrombosis between tunneled lines and peripherally inserted central catheters has not been undertaken. Children inclusion. Data were extracted from the hospital discharge database which includes data on all procedures and up to 20 diagnoses per admission. Diagnoses and procedures were identified by International Classification of Disease, Ninth Revision coding. Patients were excluded if they received more than one central line. Data collected included type of central line, deep vein thrombosis event, and underlying medical illnesses classified according to chronic complex conditions. Over the seven year study period there was an overall rate of 73 deep vein thromboses per 10,000 hospital discharges. Of the 6915 eligible subjects, 181 had a deep vein thrombosis for an overall incidence rate of 2.6%. There were 152 thrombi (2.6%) in subjects with peripherally inserted central catheters and 29 thrombi (3.1%) in subjects with tunneled lines [OR=.83 (0.55, 1.29), p=0.38]. Despite the relative ease and simplicity of use of peripherally inserted central catheters leading to a substantial rise in their use, this study demonstrates that such lines pose a substantial risk for venous thrombosis and no difference in incidence was detected between such lines and tunneled lines. © 2013.

Dynamics-based centrality for directed networks.

Science.gov (United States)

Masuda, Naoki; Kori, Hiroshi

2010-11-01

Determining the relative importance of nodes in directed networks is important in, for example, ranking websites, publications, and sports teams, and for understanding signal flows in systems biology. A prevailing centrality measure in this respect is the PageRank. In this work, we focus on another class of centrality derived from the Laplacian of the network. We extend the Laplacian-based centrality, which has mainly been applied to strongly connected networks, to the case of general directed networks such that we can quantitatively compare arbitrary nodes. Toward this end, we adopt the idea used in the PageRank to introduce global connectivity between all the pairs of nodes with a certain strength. Numerical simulations are carried out on some networks. We also offer interpretations of the Laplacian-based centrality for general directed networks in terms of various dynamical and structural properties of networks. Importantly, the Laplacian-based centrality defined as the stationary density of the continuous-time random walk with random jumps is shown to be equivalent to the absorption probability of the random walk with sinks at each node but without random jumps. Similarly, the proposed centrality represents the importance of nodes in dynamics on the original network supplied with sinks but not with random jumps.

Community centrality and social science research.

Science.gov (United States)

Allman, Dan

2015-12-01

Community centrality is a growing requirement of social science. The field's research practices are increasingly expected to conform to prescribed relationships with the people studied. Expectations about community centrality influence scholarly activities. These expectations can pressure social scientists to adhere to models of community involvement that are immediate and that include community-based co-investigators, advisory boards, and liaisons. In this context, disregarding community centrality can be interpreted as failure. This paper considers evolving norms about the centrality of community in social science. It problematises community inclusion and discusses concerns about the impact of community centrality on incremental theory development, academic integrity, freedom of speech, and the value of liberal versus communitarian knowledge. Through the application of a constructivist approach, this paper argues that social science in which community is omitted or on the periphery is not failed science, because not all social science requires a community base to make a genuine and valuable contribution. The utility of community centrality is not necessarily universal across all social science pursuits. The practices of knowing within social science disciplines may be difficult to transfer to a community. These practices of knowing require degrees of specialisation and interest that not all communities may want or have.

Central banks: Paradise lost

OpenAIRE

Issing, Otmar

2012-01-01

The focus of the paper is to analyze how the concept behind central bank policy developed over time and how the recent financial crisis and its consequences will have an influence. While the principles of the institutional arrangement for central banks (independence, clear mandate, prohibition of monetary financing) are relevant as ever, pre- crisis consensus strategies of monetary policy have been revealed as flawed. The close monitoring of money and credit developments, a key lesson to be d...

Central European gas market perspectives

International Nuclear Information System (INIS)

Vanous, Jan

1999-01-01

This presentation deals with (1) Definition of the Central European market, (2) Factors driving up consumption of natural gas in Central and Eastern Europe, (3) Role of natural gas in regional energy consumption, (4) Position of natural gas in individual country markets, (5) Future sources of imported natural gas into the region. The Central European market are the eleven countries Albania, Bulgaria, Croatia, Czech Republic, Hungary, Macedonia, Poland, Romania, Serbia and Montenegro, Slovakia, and Slovenia, with a total population of 121 million. This market is comparable to combined France and Italy in terms of population, but only 30% of its size in terms of GDP

Close-binary central stars of planetary nebulae

International Nuclear Information System (INIS)

Bond, H.E.; Grauer, A.D.

1987-01-01

Recent observations of PN central stars identified as binary systems are reviewed. The theoretical significance of binary central stars is discussed, and the characteristics of UU Sge, V 477 Lyr, MT Ser, LSS 2018, VW Pyx, and the central star of HFG 1 are briefly summarized. All of these binaries are shown to have periods less than 1 day, and it is estimated that about 10 percent of all binary central stars are close binaries. 27 references

Central Station Design Options

DEFF Research Database (Denmark)

2011-01-01

. The work identifies the architecture, sizing and siting of prospective Central Stations in Denmark, which can be located at shopping centers, large car parking lots or gas stations. Central Stations are planned to be integrated in the Danish distribution grid. The Danish island of Bornholm, where a high...... overloading, more reference points might be necessary to represent various transformer loading levels. The subject of safety in Central Station is also addressed. A number of safety rules based on European standards apply to AC charging equipment up to 44 kW. The connection interlock and the automatic de......-energization are identified as fundamental requirements for safety in such a charging station. The connection interlock is a solution which ensures that no power is applied to the DC cable when the EV connector is not connected. The automatic de-energization device ensures that whenever a strain on the cable is detected, e...

48 CFR 52.204-7 - Central Contractor Registration.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Central Contractor....204-7 Central Contractor Registration. As prescribed in 4.1105, use the following clause: Central Contractor Registration (APR 2008) (a) Definitions. As used in this clause— Central Contractor Registration...

Comparison of blood loss between using non central part cutting knee prosthesis and distal central part cutting.

Science.gov (United States)

Malairungsakul, Anan

2014-12-01

Patients who undergo knee replacement surgery may need to receive a blood transfusion due to blood loss during the operation. Therefore it was important to improve the design of knee implant operative procedures in an attempt to reduce the rate of blood loss. The present study aimed to compare the blood loss between two types of knee replacement surgery. This is a retrospective study in which 78 patients received cemented knee replacements in Phayao Hospital between October 2010 and March 2012. There were two types of surgical procedure: 1) using an implant position covering the end of the femoral bone without cutting into the central part of the distal femoral, 2) using an implant position covering the end of the femoral bone cutting the central part of the distal femoral. Blood loss, blood transfusion, hemoglobin and hematocrit were recorded preoperatively, immediately postsurgery and 48 hours after surgery. Findings revealed that the knee replacement surgery using the implant position covering the end of the femoral bone without cutting the central part of the distal femoral significantly lowered the rate of blood loss when compared to using the implant position covering the end of the femoral bone with central cutting of the distal femor. The average blood loss during the operation without cutting at the central part of distal femoral was 49.50 ± 11.11 mL; whereas the operation cutting the central part of the distal femoral was 58.50 ± 11.69 mL. As regards blood loss, the knee replacement surgery using the implant position covering the end ofthefemoral bone without cutting the central part of distal femor was better than using the implant position covering the end of the femoral bone cutting at the central part of the distal femor.

A new paradigm of modern central banking

Directory of Open Access Journals (Sweden)

Aleksandra Szunke

2013-05-01

Full Text Available The changes in the modern monetary policy, which took place at the beginning of the twenty-first century, in response to the global financial crisis led to the transformation of the place and the role of central banks. The strategic aim of the central monetary institutions has become preventing financial instability. So far, central banks have defined financial stability as a public good, which took care independently of other monetary purposes (Pyka, 2010. Unconventional monetary policy resulted in changes the global central banking. The aim of the study is to identify a new paradigm of the role and place of the central bank in the financial system and its new responsibilities, aimed at countering financial instability.

Central hypothyroidism - a neglected thyroid disorder.

Science.gov (United States)

Beck-Peccoz, Paolo; Rodari, Giulia; Giavoli, Claudia; Lania, Andrea

2017-10-01

Central hypothyroidism is a rare and heterogeneous disorder that is characterized by a defect in thyroid hormone secretion in an otherwise normal thyroid gland due to insufficient stimulation by TSH. The disease results from the abnormal function of the pituitary gland, the hypothalamus, or both. Moreover, central hypothyroidism can be isolated or combined with other pituitary hormone deficiencies, which are mostly acquired and are rarely congenital. The clinical manifestations of central hypothyroidism are usually milder than those observed in primary hypothyroidism. Obtaining a positive diagnosis for central hypothyroidism can be difficult from both a clinical and a biochemical perspective. The diagnosis of central hypothyroidism is based on low circulating levels of free T 4 in the presence of low to normal TSH concentrations. The correct diagnosis of both acquired (also termed sporadic) and congenital (also termed genetic) central hypothyroidism can be hindered by methodological interference in free T 4 or TSH measurements; routine utilization of total T 4 or T 3 measurements; concurrent systemic illness that is characterized by low levels of free T 4 and normal TSH concentrations; the use of the sole TSH-reflex strategy, which is the measurement of the sole level of TSH, without free T 4 , if levels of TSH are in the normal range; and the diagnosis of congenital hypothyroidism based on TSH analysis without the concomitant measurement of serum levels of T 4 . In this Review, we discuss current knowledge of the causes of central hypothyroidism, emphasizing possible pitfalls in the diagnosis and treatment of this disorder.

"Christofest" New Yorgi Central Parkis / Rael Artel

Index Scriptorium Estoniae

Artel, Rael, 1980-

2004-01-01

12. II 2005. a. avatakse Christo ja Jeanne-Claude'i keskkonnainstallatsioon "The Gates" New Yorgi Central Parkis. Paralleelselt toimub Metropolitan Muuseumis näitus "Christo and Jeanne-Claude : The Gates, Central Park, New York", kus eksponeeritakse Central Parki installatsiooni ettevalmistavaid materjale: joonistusi, diagramme, fotosid jne

Centrality metrics and localization in core-periphery networks

International Nuclear Information System (INIS)

Barucca, Paolo; Lillo, Fabrizio; Tantari, Daniele

2016-01-01

Two concepts of centrality have been defined in complex networks. The first considers the centrality of a node and many different metrics for it have been defined (e.g. eigenvector centrality, PageRank, non-backtracking centrality, etc). The second is related to large scale organization of the network, the core-periphery structure, composed by a dense core plus an outlying and loosely-connected periphery. In this paper we investigate the relation between these two concepts. We consider networks generated via the stochastic block model, or its degree corrected version, with a core-periphery structure and we investigate the centrality properties of the core nodes and the ability of several centrality metrics to identify them. We find that the three measures with the best performance are marginals obtained with belief propagation, PageRank, and degree centrality, while non-backtracking and eigenvector centrality (or MINRES [10], showed to be equivalent to the latter in the large network limit) perform worse in the investigated networks. (paper: interdisciplinary statistical mechanics )

Central Laboratories Services

Data.gov (United States)

Federal Laboratory Consortium — The TVA Central Laboratories Services is a comprehensive technical support center, offering you a complete range of scientific, engineering, and technical services....

RELATION BETWEEN ISLAMIC BANK AND CENTRAL BANK

OpenAIRE

PAKSOY, H. Mustafa; ABAROSS, Nour

2015-01-01

This study deals with the nature of Islamic banks and their features, and requirements of these features in terms of control tools and methods appropriate with the particularity of their business and their relation with the traditional central bank. At the same time aims to view the relationship between Islamic bank and central bank. To explain this relation the researcher started to explain what is the central bank, objectives of central bank, and characteristics, what is Islamic bank and ob...

Distributed trace using central performance counter memory

Science.gov (United States)

Satterfield, David L.; Sexton, James C.

2013-01-22

A plurality of processing cores, are central storage unit having at least memory connected in a daisy chain manner, forming a daisy chain ring layout on an integrated chip. At least one of the plurality of processing cores places trace data on the daisy chain connection for transmitting the trace data to the central storage unit, and the central storage unit detects the trace data and stores the trace data in the memory co-located in with the central storage unit.

Accountability of Central Banks : Aspects and Quantification

NARCIS (Netherlands)

de Haan, J.; Amtenbrink, F.; Eijffinger, S.C.W.

1998-01-01

This paper starts with a discussion of the various aspects of accountability of central banks. On the basis of this discussion we construct an indicator for accountability for 16 central banks, including the European Central Bank. It is shown that the degree of accountability differs considerably

48 CFR 18.102 - Central contractor registration.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Central contractor... Central contractor registration. Contractors are not required to be registered in the Central Contractor.... (See 4.1102). However, contractors are required to register with CCR in order to gain access to the...

Closed central slip injuries--a missed diagnosis?

LENUS (Irish Health Repository)

Nugent, N

2011-09-01

The extensor apparatus of the finger is a complex structure and injury can lead to significant digital dysfunction. Closed central slip injuries may be missed or diagnosis delayed because of lack of an open wound and often no radiographic abnormality, and can result in boutonniere deformities if untreated. This study aimed to quantify the number of patients attending with closed central slip injuries and to ascertain if the initial diagnosis was correct. The number of patients presenting to us over a 6 month period was recorded. The original diagnosis, time to diagnosis of central slip injury and the presence\\/absence of a boutonniere deformity were recorded. Ten patients were included in the study. Seven (70%) injuries were due to sport. Eight (80%) had a delayed diagnosis of central slip injury. Six (60%) had previously presented to general practitioners or emergency departments. Seven (70%) had boutonniere deformities. Closed central slip injuries can be missed. Simple clinical tests can diagnose central slip disruption.

Central Pain Syndrome

Science.gov (United States)

... such as neurontin (gabapentin) can be useful. Lowering stress levels appears to reduce pain. View Full Treatment Information Definition Central pain syndrome is a neurological condition caused ...

The Correlation of Sovereign Rating and Bonds’ Interest Rate in EU Member States

Directory of Open Access Journals (Sweden)

Emilian-Constantin MIRICESCU

2015-06-01

Full Text Available The importance of borrowing is fundamental for central public administration and it consists in sources of f nancing budget def cit and ref nanc-ing government debt. In the last years, a lot of countries had diff culties regarding the payment of public loans at their maturity due to the burden of government debt to GDP ratio. In this situa-tion, investors lose their conf dence not only in the country that is facing problems, but also in other states that pay their debt at maturity. For this reason, they are careful at any change that affects sovereign rating. From our investigation we found that sover-eign rating has a negative inf uence on bonds’ interest rate. As such, decision makers from central public administration should focus on improving sovereign ratings in order to decrease interest rates.

Centralized digital control of accelerators

International Nuclear Information System (INIS)

Melen, R.E.

1983-09-01

In contrasting the title of this paper with a second paper to be presented at this conference entitled Distributed Digital Control of Accelerators, a potential reader might be led to believe that this paper will focus on systems whose computing intelligence is centered in one or more computers in a centralized location. Instead, this paper will describe the architectural evolution of SLAC's computer based accelerator control systems with respect to the distribution of their intelligence. However, the use of the word centralized in the title is appropriate because these systems are based on the use of centralized large and computationally powerful processors that are typically supported by networks of smaller distributed processors

Fast network centrality analysis using GPUs

Directory of Open Access Journals (Sweden)

Shi Zhiao

2011-05-01

Full Text Available Abstract Background With the exploding volume of data generated by continuously evolving high-throughput technologies, biological network analysis problems are growing larger in scale and craving for more computational power. General Purpose computation on Graphics Processing Units (GPGPU provides a cost-effective technology for the study of large-scale biological networks. Designing algorithms that maximize data parallelism is the key in leveraging the power of GPUs. Results We proposed an efficient data parallel formulation of the All-Pairs Shortest Path problem, which is the key component for shortest path-based centrality computation. A betweenness centrality algorithm built upon this formulation was developed and benchmarked against the most recent GPU-based algorithm. Speedup between 11 to 19% was observed in various simulated scale-free networks. We further designed three algorithms based on this core component to compute closeness centrality, eccentricity centrality and stress centrality. To make all these algorithms available to the research community, we developed a software package gpu-fan (GPU-based Fast Analysis of Networks for CUDA enabled GPUs. Speedup of 10-50× compared with CPU implementations was observed for simulated scale-free networks and real world biological networks. Conclusions gpu-fan provides a significant performance improvement for centrality computation in large-scale networks. Source code is available under the GNU Public License (GPL at http://bioinfo.vanderbilt.edu/gpu-fan/.

Microsurgical anatomy of the central lobe.

Science.gov (United States)

Frigeri, Thomas; Paglioli, Eliseu; de Oliveira, Evandro; Rhoton, Albert L

2015-03-01

The central lobe consists of the pre- and postcentral gyri on the lateral surface and the paracentral lobule on the medial surface and corresponds to the sensorimotor cortex. The objective of the present study was to define the neural features, craniometric relationships, arterial supply, and venous drainage of the central lobe. Cadaveric hemispheres dissected using microsurgical techniques provided the material for this study. The coronal suture is closer to the precentral gyrus and central sulcus at its lower rather than at its upper end, but they are closest at a point near where the superior temporal line crosses the coronal suture. The arterial supply of the lower two-thirds of the lateral surface of the central lobe was from the central, precentral, and anterior parietal branches that arose predominantly from the superior trunk of the middle cerebral artery. The medial surface and the superior third of the lateral surface were supplied by the posterior interior frontal, paracentral, and superior parietal branches of the pericallosal and callosomarginal arteries. The venous drainage of the superior two-thirds of the lateral surface and the central lobe on the medial surface was predominantly through the superior sagittal sinus, and the inferior third of the lateral surface was predominantly through the superficial sylvian veins to the sphenoparietal sinus or the vein of Labbé to the transverse sinus. The pre- and postcentral gyri and paracentral lobule have a morphological and functional anatomy that differentiates them from the remainder of their respective lobes and are considered by many as a single lobe. An understanding of the anatomical relationships of the central lobe can be useful in preoperative planning and in establishing reliable intraoperative landmarks.

Several Centuries of Centrality

OpenAIRE

Dana L. Roth

2015-01-01

As Carolyn Bertozzi mentioned in her inaugural editorial, the relationship of “Central Science” to “Chemistry” became popularized over 40 years ago with the publication of the first edition of Brown and LeMay’s Chemistry: The Central Science, now in its 13th edition. Yet as late as 2003, Prof. Sason Shaik at The Hebrew University claimed “popularization of chemistry remains scant.” He goes on to share [his] “own experience of popularizing chemistry by delivering the following universal messag...

Central Chile

Science.gov (United States)

2002-01-01

The beginning of spring in central Chile looked like this to SeaWiFS. The snow-covered Andes mark the country's eastern border, and phytoplankton blooms and river sediment plumes fill the waters off its west coast. A large eddy due west of Concepcion is highlighted by the phytoplankton it contains.

Analyzing complex networks through correlations in centrality measurements

International Nuclear Information System (INIS)

Ricardo Furlan Ronqui, José; Travieso, Gonzalo

2015-01-01

Many real world systems can be expressed as complex networks of interconnected nodes. It is frequently important to be able to quantify the relative importance of the various nodes in the network, a task accomplished by defining some centrality measures, with different centrality definitions stressing different aspects of the network. It is interesting to know to what extent these different centrality definitions are related for different networks. In this work, we study the correlation between pairs of a set of centrality measures for different real world networks and two network models. We show that the centralities are in general correlated, but with stronger correlations for network models than for real networks. We also show that the strength of the correlation of each pair of centralities varies from network to network. Taking this fact into account, we propose the use of a centrality correlation profile, consisting of the values of the correlation coefficients between all pairs of centralities of interest, as a way to characterize networks. Using the yeast protein interaction network as an example we show also that the centrality correlation profile can be used to assess the adequacy of a network model as a representation of a given real network. (paper)

JPRS Report, Science & Technology, Japan

Science.gov (United States)

1988-03-03

function of nematodes and Mitsubishi Electric Corp. is researching the nervous system of the sea hare. This research is aimed at clarify- ing the...First Clean roon Direct nold- ing with 50/jffi aoeuraey ■-» •: Final inspee lion ins Laser To nark- «_ Final ing size inspeo- .- vacuun...transportation of radioactive substances and Y3.7 mil- lion to confirm the safety of transportation of radioac- tive substances. It will also spend Y3

Central voice production and pathophysiology of spasmodic dysphonia.

Science.gov (United States)

Mor, Niv; Simonyan, Kristina; Blitzer, Andrew

2018-01-01

Our ability to speak is complex, and the role of the central nervous system in controlling speech production is often overlooked in the field of otolaryngology. In this brief review, we present an integrated overview of speech production with a focus on the role of central nervous system. The role of central control of voice production is then further discussed in relation to the potential pathophysiology of spasmodic dysphonia (SD). Peer-review articles on central laryngeal control and SD were identified from PUBMED search. Selected articles were augmented with designated relevant publications. Publications that discussed central and peripheral nervous system control of voice production and the central pathophysiology of laryngeal dystonia were chosen. Our ability to speak is regulated by specialized complex mechanisms coordinated by high-level cortical signaling, brainstem reflexes, peripheral nerves, muscles, and mucosal actions. Recent studies suggest that SD results from a primary central disturbance associated with dysfunction at our highest levels of central voice control. The efficacy of botulinum toxin in treating SD may not be limited solely to its local effect on laryngeal muscles and also may modulate the disorder at the level of the central nervous system. Future therapeutic options that target the central nervous system may help modulate the underlying disorder in SD and allow clinicians to better understand the principal pathophysiology. NA.Laryngoscope, 128:177-183, 2018. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.

Geometric origin of central charges

International Nuclear Information System (INIS)

Lukierski, J.; Rytel, L.

1981-05-01

The complete set of N(N-1) central charge generators for D=4 N-extended super Poincare algebra is obtained by suitable contraction of OSp (2N; 4) superalgebra. The superspace realizations of the spinorial generators with central charges are derived. The conjugate set of N(N-1) additional bosonic superspace coordinates is introduced in an unique and geometric way. (author)

The Jurassic of Denmark and Greenland: Sedimentology and sequence stratigraphy of paralic and shallow marine Upper Jurassic sandstones in the northern Danish Central Graben

Directory of Open Access Journals (Sweden)

Johannessen, Peter N.

2003-10-01

Full Text Available Paralic and shallow marine sandstones were deposited in the Danish Central Graben during Late Jurassic rifting when half-grabens were developed and the overall eustatic sea level rose. During the Kimmeridgian, an extensive plateau area consisting of the Heno Plateau and the Gertrud Plateau was situated between two highs, the Mandal High to the north, and the combined Inge and Mads Highs to the west. These highs were land areas situated on either side of the plateaus and supplied sand to the Gertrud and Heno Plateaus. Two graben areas, the Feda and Tail End Grabens, flanked the plateau area to the west and east, respectively. The regressive–ransgressive succession consists of intensely bioturbated shoreface sandstones, 25–75 m thick. Two widespread unconformities (SB1, SB2 are recognised on the plateaus, forming the base of sequence 1 and sequence 2, respectively. These unconformities were created by a fall in relative sea level during which rivers may have eroded older shoreface sands and transported sediment across the Heno andGertrud Plateaus, resulting in the accumulation of shoreface sandstones farther out in the Feda and Tail End Grabens, on the south-east Heno Plateau and in the Salt Dome Province. Duringsubsequent transgression, fluvial sediments were reworked by high-energy shoreface processes on the Heno and Gertrud Plateaus, leaving only a lag of granules and pebbles on the marine transgressive surfaces of erosion (MTSE1, MTSE2.The sequence boundary SB1 can be traced to the south-east Heno Plateau and the Salt Dome Province, where it is marked by sharp-based shoreface sandstones. During low sea level, erosion occurred in the southern part of the Feda Graben, which formed part of the Gertrud and Heno Plateaus, and sedimentation occurred in the Norwegian part of the Feda Graben farther to the north. During subsequent transgression, the southern part of the Feda Graben began to subside, and a succession of backstepping back

Afrique Centrale

African Journals Online (AJOL)

PR BOKO

(Afrique Centrale) : peuplement de protozoaires ciliés et macro invertébrés ... Le lac d'Obili est un écosystème aquatique situé en plein cœur de Yaoundé en ...... électrique des eaux est assez stable, autour de 200 ; ce qui suppose que la ...

Atmospheres of central stars

International Nuclear Information System (INIS)

Hummer, D.G.

1978-01-01

The author presents a brief summary of atmospheric models that are of possible relevance to the central stars of planetary nebulae, and then discusses the extent to which these models accord with the observations of both nebulae and central stars. Particular attention is given to the significance of the very high Zanstra temperature implied by the nebulae He II lambda 4686 A line, and to the discrepancy between the Zanstra He II temperature and the considerably lower temperatures suggested by the appearance of the visual spectrum for some of these objects. (Auth.)

Representation of Central Asia and Traveling Self in Vambery’s Travels in Central Asia

Directory of Open Access Journals (Sweden)

Ahmad Gholi

2016-03-01

Full Text Available In the course of the nineteenth century Arminius Vambery, an anglophile travel writer, in the guise of a mendicant dervish with a group of Tartar pilgrims departs to secluded and sealed Central Asia. After six months travel in the Khanates of Central Asia, he undertakes a journey to England where he offers his observations to the Royal Geographical Society and publishes his travelogue, Travel in Central Asia. Despite its literary merits and connection with British imperialism, the travelogue has not been scrutinized separately by the scholars of travel writing. To fill the gap, this article by drawing on the theories of post-structuralism: Orientalism and Postcolonialism, endeavors to unveil the political agenda behind the travel writer’s representation of his travelees, destination, and his own traveling self. Additionally, it argues that the travel writer in dialogue with other Western travel writers to deterritorialize his traversed region or justify the prospective presence of Britain in Central Asia, represents his journey destination as the locus of barbarity, a region under the grip of despotic rulers, as well as an area with frozen time, while to exhibit his Eurocentrism, he portrays his traveling subject as the a suffering hero and a benign traveler.

What makes you more central? : antecedents of changes in betweenness-centrality in technology-based alliance networks

NARCIS (Netherlands)

Gilsing, V.A.; Cloodt, M.M.A.H.; Bertrand-Cloodt, D.A.M.

2016-01-01

Although central network positions have been associated with above average performance effects, an important void that still remains is how firms come to occupy a more central position in the first place. Whereas recently made exogenous explanations have shed some more light on aggregate changes in

Vandellos-2: third generation of NPPs becomes reality

International Nuclear Information System (INIS)

Camps, M.; Vallejo, J.M.

1988-01-01

When Vandellos-2 was officially declared in operation (March 3, 1988), the third generation of nuclear power plants became a reality in Spain. Located in Tarragona province on the Mediterranian coast, Vandellos-2 has demonstrated the value of developing working partnership among all participants in building a country's nuclear program. Vandellos-2 was planned and built by the Asociacion Nuclear Vandellos (ANV), comprising the utilities ENDESA (72 %) and Hidroelectrica Espanola (28 %). The unit has a 2785 MWth three-loop Westinghouse PWR feeding a Westinghouse turbine-generator with a gross power of 982 MWe. To obtain a competitive nuclear cost per kWh for the completed plant, ANV has carefully controlled all aspects of the project as well as monitoring hardware and construction costs. ANV's success in keeping the project on schedule was aided by Spanish industry's 25 years of experience in nuclear construction. 2 tabs

Central venous obstruction in the thorax

International Nuclear Information System (INIS)

Collin, G.; Jones, R.G.; Willis, A.P.

2015-01-01

Central venous stenosis and occlusion can occur secondary to a spectrum of conditions ranging from aggressive malignancy to benign extrinsic anatomical compression in otherwise healthy individuals. Irrespective of aetiology, significant morbidity in the acute setting and long term can occur unless prompt accurate diagnosis and appropriate management is initiated, the radiologist being central to both. The present review will provide radiologists with a thorough illustration and explanation of the range of central venous conditions in the thorax (including deep vein thrombosis, thoracic outlet syndrome, haemodialysis, and malignancy related causes), the salient imaging findings and interventional management using case examples from the authors' practice. - Highlights: • We show a range of causes of central venous disease in the thorax. • We provide information about different imaging and management strategies. • We show several cases with successes and complications of endovascular management

Central station market development strategies for photovoltaics

Science.gov (United States)

1980-01-01

Federal market development strategies designed to accelerate the market penetration of central station applications of photovoltaic energy system are analyzed. Since no specific goals were set for the commercialization of central station applications, strategic principles are explored which, when coupled with specific objectives for central stations, can produce a market development implementation plan. The study includes (1) background information on the National Photovoltaic Program, photovoltaic technology, and central stations; (2) a brief market assessment; (3) a discussion of the viewpoints of the electric utility industry with respect to solar energy; (4) a discussion of commercialization issues; and (5) strategy principles. It is recommended that a set of specific goals and objectives be defined for the photovoltaic central station program, and that these goals and objectives evolve into an implementation plan that identifies the appropriate federal role.

Insulin versus Lipid Emulsion in a Rabbit Model of Severe Propranolol Toxicity: A Pilot Study

Directory of Open Access Journals (Sweden)

Martyn Harvey

2011-01-01

Full Text Available Background and objective. Beta-blocker overdose may result in intractable cardiovascular collapse despite conventional antidotal treatments. High dose insulin/glucose (ING, and more recently intravenous lipid emulsion (ILE, have been proposed as potentially beneficial therapies in beta blocker intoxication. We compare efficacy of the novel antidotes ING, with ILE, in a rabbit model of combined enteric/intravenous propranolol toxicity. Methods. Sedated, mechanically ventilated and invasively monitored New Zealand White rabbits underwent mini-laparotomy and enterostomy formation with 40 mg/kg propranolol instilled into the proximal small bowel. At 30 minutes propranolol infusion was commenced at 4 mg/kg/hr and continued to a target mean arterial pressure (MAP of 50% baseline MAP. Animals were resuscitated with insulin at 3 U/kg plus 0.5 g/kg glucose (ING group, or 10 mL/kg 20% Intralipid (ILE group. Results. Rate pressure product (RPP; RPP = heart rate × mean arterial pressure was greatest in the ING group at 60 minutes (P<.05. A trend toward greater heart rate was observed in the ING group (P=.06. No difference was observed in survival between groups (4/5 ING versus 2/5 ILE; P=.524. Conclusions. High dose insulin resulted in greater rate pressure product compared with lipid emulsion in this rabbit model of severe enteric/intravenous propranolol toxicity.

California's Central Valley Groundwater Study: A Powerful New Tool to Assess Water Resources in California's Central Valley

Science.gov (United States)

Faunt, Claudia C.; Hanson, Randall T.; Belitz, Kenneth; Rogers, Laurel

2009-01-01

Competition for water resources is growing throughout California, particularly in the Central Valley. Since 1980, the Central Valley's population has nearly doubled to 3.8 million people. It is expected to increase to 6 million by 2020. Statewide population growth, anticipated reductions in Colorado River water deliveries, drought, and the ecological crisis in the Sacramento-San Joaquin Delta have created an intense demand for water. Tools and information can be used to help manage the Central Valley aquifer system, an important State and national resource.

Interest Rate Policy Of Selected Central Banks In Central And Eastern Europe

Directory of Open Access Journals (Sweden)

GRABIA TOMASZ

2015-03-01

Full Text Available The aim of this article is to present and evaluate interest rate policies of three selected central banks in Central and Eastern Europe (Poland, the Czech Republic, and Hungary from 2001 to 2013. The study consists of an introduction (Section 1 and three main parts. The introduction contains a theoretical description of the role of interest rate policy, the dilemmas connected with it, as well as an analysis of the strategies and goals of monetary policies of the National Bank of Poland (NBP, the Czech National Bank (CzNB, and the National Bank of Hungary (NBH in the context of existing legal and institutional conditions. In turn, the first empirical part (Section 2 examines how the analysed central banks responded to changes in inflation, unemployment, and economic growth rates. The tools of the analysis are the nominal and real interest rates of those banks. The subsequent research part (Section 3 attempts to evaluate the degree of the contractionary nature of interest rate policies in specific countries in the context of the Taylor rule. The text ends with a summary (Section 4 encompassing concise conclusions drawn from the earlier analyses.

D Central Line Extraction of Fossil Oyster Shells

Science.gov (United States)

Djuricic, A.; Puttonen, E.; Harzhauser, M.; Mandic, O.; Székely, B.; Pfeifer, N.

2016-06-01

Photogrammetry provides a powerful tool to digitally document protected, inaccessible, and rare fossils. This saves manpower in relation to current documentation practice and makes the fragile specimens more available for paleontological analysis and public education. In this study, high resolution orthophoto (0.5 mm) and digital surface models (1 mm) are used to define fossil boundaries that are then used as an input to automatically extract fossil length information via central lines. In general, central lines are widely used in geosciences as they ease observation, monitoring and evaluation of object dimensions. Here, the 3D central lines are used in a novel paleontological context to study fossilized oyster shells with photogrammetric and LiDAR-obtained 3D point cloud data. 3D central lines of 1121 Crassostrea gryphoides oysters of various shapes and sizes were computed in the study. Central line calculation included: i) Delaunay triangulation between the fossil shell boundary points and formation of the Voronoi diagram; ii) extraction of Voronoi vertices and construction of a connected graph tree from them; iii) reduction of the graph to the longest possible central line via Dijkstra's algorithm; iv) extension of longest central line to the shell boundary and smoothing by an adjustment of cubic spline curve; and v) integration of the central line into the corresponding 3D point cloud. The resulting longest path estimate for the 3D central line is a size parameter that can be applied in oyster shell age determination both in paleontological and biological applications. Our investigation evaluates ability and performance of the central line method to measure shell sizes accurately by comparing automatically extracted central lines with manually collected reference data used in paleontological analysis. Our results show that the automatically obtained central line length overestimated the manually collected reference by 1.5% in the test set, which is deemed

Central Bank Independence, Transparency and Accountability Indexes: a Survey

Directory of Open Access Journals (Sweden)

Dumiter Florin Cornel

2014-06-01

Full Text Available Recently, the remarkable trend upon central bank independence and the efficient monetary policy were seriously highlighted in the monetary economics field. Starting from 1990s’ central bank independence was at the core of policy making and central banking problems, because of the widespread economical, political, personal and budgetary autonomy of the central bank. Nowadays, we can observe an increasing trend upon central bank transparency, for evaluating more accurate the central bank’s performances by the wide public, mass-media and financial markets. Consequently, a central bank must encompass a high degree of accountability and responsibility, because of the final liability in case of failure. In this paper we present, analyze and assess the construction of the most important indices regarding central bank independence, transparency and accountability in a chronological manner, presenting also the advantages and disadvantages of these indices related to actual practices of central banks. Moreover, we analyze the analytical results of the empirical testing of these indices with a considerable impact upon the developed and developing country group. In regard with the empirical results of different authors, we suggest the importance and the necessity for constructing an aggregate index for measuring central bank independence, transparency and accountability, based on de jure stipulations and the actual practices of the central banks.

CENTRAL PLATEAU REMEDIATION OPTIMIZATION STUDY

Energy Technology Data Exchange (ETDEWEB)

BERGMAN, T. B.; STEFANSKI, L. D.; SEELEY, P. N.; ZINSLI, L. C.; CUSACK, L. J.

2012-09-19

THE CENTRAL PLATEAU REMEDIATION OPTIMIZATION STUDY WAS CONDUCTED TO DEVELOP AN OPTIMAL SEQUENCE OF REMEDIATION ACTIVITIES IMPLEMENTING THE CERCLA DECISION ON THE CENTRAL PLATEAU. THE STUDY DEFINES A SEQUENCE OF ACTIVITIES THAT RESULT IN AN EFFECTIVE USE OF RESOURCES FROM A STRATEGIC PERSPECTIVE WHEN CONSIDERING EQUIPMENT PROCUREMENT AND STAGING, WORKFORCE MOBILIZATION/DEMOBILIZATION, WORKFORCE LEVELING, WORKFORCE SKILL-MIX, AND OTHER REMEDIATION/DISPOSITION PROJECT EXECUTION PARAMETERS.

"Central Station" Londonis

Index Scriptorium Estoniae

2000-01-01

Londoni galeriis Milch seitsme läti, leedu ja eesti kunstniku projekt "Central Station". Kuraatorid Lisa Panting, Sally Tallant. Eestist osalevad Hanno Soans (Catarina Campinoga koostöös valminud video), Kiwa, Kai Kaljo

Central Pontine Myelinolysis

Science.gov (United States)

... Clinical Trials Organizations Publications Definition Central pontine myelinolysis (CPM) is a neurological disorder that most frequently occurs ... Experts estimate that 10 percent of those with CPM will also have areas of EPM. The initial ...

[Centralization in obstetrics: pros and cons].

Science.gov (United States)

Roemer, V M; Ramb, S

1996-01-01

Possible advantages and disadvantages of a general centralization of German obstetric facilities are analysed in the study. The need for centralization of risk cases, especially premature births (regionalization) is pointed out. Centralization appears appropriate, since every fifth maternity unit in Germany (19.78%) has 300 or fewer deliveries per year. This one fifth of perinatal clinics accounts for 6.3% of all deliveries (N = 49450). There are appreciable differences between the old and new federal states (Bundesländer): in the recently acceded federal states, 48.7% of all perinatal clinics have deliveries of 300 and less per year. This group of perinatal clinics accounts for 29% of all deliveries in the new federal states. We have carried out a survey of the mother's attitude to centralization: out of 416 patients in the Detmold women's hospital whose mean age was 29.0 +/- 4.2 years, 90.4% were not in favor of general centralization of obstetrics. 43% were also against a centralization of risk cases (regionalization). 75% of the women surveyed objected to centralized obstetrics because of the 'possible absence of the family', the 'possible absence of students and trainees' (44.9%), the 'unfamiliarity with staff and premises' (41.8%) and 'fear of anonymity' (44.5%). The majority of all women (84.1%) did not want to have a drive more than 20 km to an obstetrics center. Fear of 'delivery in a taxi'(78.6%), the 'fear that the husband will come too late to the delivery' (65.4%) and that the 'overall course of the delivery might not be adequate for reasons of time'. The presence of a pediatrics department in conjunction with the perinatal clinic was rated very positively (93%). It is concluded from the data and further juridical considerations that centralization of risk cases (regionalization) is indispensable in the near future and that somewhat more further into the future decentralization should be carried out by closing obstetrics departments with substantially

District Central Office Leadership as Teaching: How Central Office Administrators Support Principals' Development as Instructional Leaders

Science.gov (United States)

Honig, Meredith I.

2012-01-01

Purpose: Research on educational leadership underscores the importance of principals operating as instructional leaders and intensive job-embedded supports for such work; this research also identifies central office staff as key support providers. However, it teaches little about what central office staff do when they provide such support and how…

Modelling Central Bank Independence and Inflation: Deus Ex Machina?

Directory of Open Access Journals (Sweden)

Dumiter Florin

2015-11-01

Full Text Available Central bank independence represents the core element of assessing the complex relationship between government and central bank, having at background the fundamental issue of a free monetary policy decision-making process from the hands of the political circle. However, central bank independence is a multilevel concept within some social, economic and behavioral implications both for the central banks and for the society at whole. Central bank independence is needed in order to establish an autonomous central bank with a high degree of freedom in choosing its’ instruments, objectives, techniques and tactics. Moreover, a high degree of transparency for the public disclosure and monitoring of central bank operation and transaction is needed for the social barometer of the central bank. Consequently the central bank must have a high degree of accountability and responsibility vis - á - vis of the most democratic institution, i.e. Parliament. In this article it is presented a comprehensive study regarding the complex relationship between central bank independence and inflation by modeling these two monetary policy panacea, in order to make a fine tuning regarding the causal relationship established in a heterodox manner.

CENTRAL ROTATIONS OF MILKY WAY GLOBULAR CLUSTERS

International Nuclear Information System (INIS)

Fabricius, Maximilian H.; Rukdee, Surangkhana; Saglia, Roberto P.; Bender, Ralf; Hopp, Ulrich; Thomas, Jens; Williams, Michael J.; Noyola, Eva; Opitsch, Michael

2014-01-01

Most Milky Way globular clusters (GCs) exhibit measurable flattening, even if on a very low level. Both cluster rotation and tidal fields are thought to cause this flattening. Nevertheless, rotation has only been confirmed in a handful of GCs, based mostly on individual radial velocities at large radii. We are conducting a survey of the central kinematics of Galactic GCs using the new Integral Field Unit instrument VIRUS-W. We detect rotation in all 11 GCs that we have observed so far, rendering it likely that a large majority of the Milky Way GCs rotate. We use published catalogs of GCs to derive central ellipticities and position angles. We show that in all cases where the central ellipticity permits an accurate measurement of the position angle, those angles are in excellent agreement with the kinematic position angles that we derive from the VIRUS-W velocity fields. We find an unexpected tight correlation between central rotation and outer ellipticity, indicating that rotation drives flattening for the objects in our sample. We also find a tight correlation between central rotation and published values for the central velocity dispersion, most likely due to rotation impacting the old dispersion measurements

Fulltext PDF

Indian Academy of Sciences (India)

ing systems. 421. CFD. Crystallization: ... able stainless steel for aircraft applications 3. Diamond ... Efficient control of servo pneumatic actuator system utilizing by-pass valve and digital slid- ing mode. 187 ... Environmental safety. Regulatory ...

On the centrality of some graphs

Directory of Open Access Journals (Sweden)

Vecdi Aytac

2017-10-01

Full Text Available A central issue in the analysis of complex networks is the assessment of their stability and vulnerability. A variety of measures have been proposed in the literature to quantify the stability of networks and a number of graph-theoretic parameters have been used to derive formulas for calculating network reliability. Different measures for graph vulnerability have been introduced so far to study different aspects of the graph behavior after removal of vertices or links such as connectivity, toughness, scattering number, binding number, residual closeness and integrity. In this paper, we consider betweenness centrality of a graph. Betweenness centrality of a vertex of a graph is portion of the shortest paths all pairs of vertices passing through a given vertex. In this paper, we obtain exact values for betweenness centrality for some wheel related graphs namely gear, helm, sunflower and friendship graphs.

Computing betweenness centrality in external memory

DEFF Research Database (Denmark)

Arge, Lars; Goodrich, Michael T.; Walderveen, Freek van

2013-01-01

Betweenness centrality is one of the most well-known measures of the importance of nodes in a social-network graph. In this paper we describe the first known external-memory and cache-oblivious algorithms for computing betweenness centrality. We present four different external-memory algorithms...

Central bank independence and financial instability

NARCIS (Netherlands)

Klomp, J.G.; de Haan, J.

2009-01-01

It has been argued that central bank independence (CBI) may not only be beneficial for reaching the objective of price stability, but also for maintaining financial stability. Greater independence from external pressure implies that central banks are less politically constrained in acting to prevent

Central nervous system

Science.gov (United States)

The central nervous system is composed of the brain and spinal cord. Your brain and spinal cord serve as the main "processing center" for your entire nervous system. They control all the workings of your body.

Finasteride for chronic central serous chorioretinopathy.

Science.gov (United States)

Forooghian, Farzin; Meleth, Annal D; Cukras, Catherine; Chew, Emily Y; Wong, Wai T; Meyerle, Catherine B

2011-04-01

To evaluate the safety and efficacy of finasteride, an inhibitor of dihydrotestosterone synthesis, in the treatment of chronic central serous chorioretinopathy. Five patients with chronic central serous chorioretinopathy were prospectively enrolled in this pilot study. Patients were administered finasteride (5 mg) daily for 3 months, after which study medication was withheld and patients were observed for 3 months. Main outcome measures included best-corrected visual acuity, central subfield macular thickness, and subretinal fluid volume as assessed by optical coherence tomography. Serum dihydrotestosterone, serum testosterone, and urinary cortisol were also measured. There was no change in mean best-corrected visual acuity. Mean center-subfield macular thickness and subretinal fluid volume reached a nadir at 3 months and rose to levels that were below baseline by 6 months. The changes in both optical coherence tomography parameters paralleled those in serum dihydrotestosterone level. In four patients, center-subfield macular thickness and/or subretinal fluid volume increased after discontinuation of finasteride. In the remaining patient, both optical coherence tomography parameters normalized with finasteride and remained stable when the study medication was discontinued. Finasteride may represent a novel medical treatment for chronic central serous chorioretinopathy. Larger controlled clinical trials are needed to further assess the efficacy of finasteride for the treatment of central serous chorioretinopathy.

(De)centralization of the global informational ecosystem

OpenAIRE

Möller, Johanna; Rimscha, M. Bjørn von

2017-01-01

Centralization and decentralization are key concepts in debates that focus on the (anti)democratic character of digital societies. Centralization is understood as the control over communication and data flows, and decentralization as giving it (back) to users. Communication and media research focuses on centralization put forward by dominant digital media platforms, such as Facebook and Google, and governments. Decentralization is investigated regarding its potential in civil society, i.e., h...

Centrality and Creativity:

DEFF Research Database (Denmark)

Andersen, Kristina Vaarst; Lorenzen, Mark

2009-01-01

To provide new insights into urban hierarchy, this article brings together one of economic geography’s oldest and most well-established notions with one of its newest and most disputed notions: Christäller’s centrality and Florida’s creative class. Using a novel original database, the article...... compares the distribution of the general population and the creative class across 444 city regions in 8 European countries. It finds that the two groups are both distributed according to the rank-size rule, but exhibit different distinct phases with different slopes. The article argues that the two...... distributions are different because market thresholds for creative services and jobs are lower than thresholds for less specialized services and jobs. The article hence concludes that centrality exerts a strong influence upon urban hierarchies of creativity and that the study of creative urban city hierarchies...

Central Asia's Raging Waters: The Prospects of Water Conflict in Central Asia

National Research Council Canada - National Science Library

Hartman, William B

2007-01-01

.... The thesis analyzes these three political eras of Central Asian history using indicators of water conflict, including water quality, water quantity, water management for multiple uses, political...

Health challenges in Kazakhstan and Central Asia.

Science.gov (United States)

Adambekov, Shalkar; Kaiyrlykyzy, Aiym; Igissinov, Nurbek; Linkov, Faina

2016-01-01

The Central Asian region, which encompasses Kazakhstan, Uzbekistan, Tajikistan, Turkmenistan and Kyrgyzstan, is an interesting geographic region with a rich history dating back to the Silk Road, Mongol conquests and expansion of the Russian Empire. However, from a public health viewpoint, the Central Asian region is under-investigated, and many public health challenges exist, as countries of Central Asia inherited the centralised medical systems practiced in the Soviet Union, and are currently undergoing rapid transitions. A large number of low and middle-income countries around the world, including countries of Central Asia, face a double burden of chronic and infectious disease. This essay focuses on the exploration of the most important public health challenges in the Central Asian region, including limited scientific productivity, the double burden of chronic and infectious disease, the need for healthcare reform and the reduction in care variation. Central Asia has a large number of medical schools, medical centres, and emerging research institutes that can be used to foster a change in medical and public health practice in the region. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Central Rotations of Milky Way Globular Clusters

Science.gov (United States)

Fabricius, Maximilian H.; Noyola, Eva; Rukdee, Surangkhana; Saglia, Roberto P.; Bender, Ralf; Hopp, Ulrich; Thomas, Jens; Opitsch, Michael; Williams, Michael J.

2014-06-01

Most Milky Way globular clusters (GCs) exhibit measurable flattening, even if on a very low level. Both cluster rotation and tidal fields are thought to cause this flattening. Nevertheless, rotation has only been confirmed in a handful of GCs, based mostly on individual radial velocities at large radii. We are conducting a survey of the central kinematics of Galactic GCs using the new Integral Field Unit instrument VIRUS-W. We detect rotation in all 11 GCs that we have observed so far, rendering it likely that a large majority of the Milky Way GCs rotate. We use published catalogs of GCs to derive central ellipticities and position angles. We show that in all cases where the central ellipticity permits an accurate measurement of the position angle, those angles are in excellent agreement with the kinematic position angles that we derive from the VIRUS-W velocity fields. We find an unexpected tight correlation between central rotation and outer ellipticity, indicating that rotation drives flattening for the objects in our sample. We also find a tight correlation between central rotation and published values for the central velocity dispersion, most likely due to rotation impacting the old dispersion measurements. This Letter includes data taken at The McDonald Observatory of The University of Texas at Austin.

Decentralization or centralization: striking a balance.

Science.gov (United States)

Dirschel, K M

1994-09-01

An Executive Vice President for Nursing can provide the necessary link to meet diverse clinical demands when encountering centralization--decentralization decisions. Centralized communication links hospital departments giving nurses a unified voice. Decentralization acknowledges the need for diversity and achieves the right balance of uniformity through a responsive communications network.

Testing the Predictions of the Central Capacity Sharing Model

Science.gov (United States)

Tombu, Michael; Jolicoeur, Pierre

2005-01-01

The divergent predictions of 2 models of dual-task performance are investigated. The central bottleneck and central capacity sharing models argue that a central stage of information processing is capacity limited, whereas stages before and after are capacity free. The models disagree about the nature of this central capacity limitation. The…

NCEP Central Operations

Science.gov (United States)

) NCO Organizational Chart NOAA's Weather and Climate Operational Supercomputing System is known as Climate Climate Prediction Climate Archives Weather Safety Storm Ready NOAA Central Library Photo Library NCO's MISSION * Execute the NCEP operational model suite - Create climate, weather, ocean, space and

Natural ionizing system to electrical protection and energy; Sistema ionizante natural de proteccion electrica y energias

Energy Technology Data Exchange (ETDEWEB)

Cabareda Fermin; Luis [Universidad de Los Andes (Venezuela)]. E-mail: lcabaredaf@gmail.com

2013-03-15

This is the new highest technology, 100% Venezuelan and unique in the world, technological innovation, world patent for maximum protection, security and zero risk (0) to all electrical and power generation systems: hydroelectric and thermoelectric power plants, wind, nuclear and solar power plants, etc; it's the only technology around the world that has the potential to disperse and propagate to land mass the enormous energies associated to the atmospheric discharges (lightning), which are in the order: 200,000 to 500,000 Amperes; 1,000 million Kilowatts and high-level transient voltage of 100 million Volts. This new high technology is the solution to the paradigm of Benjamin Franklin and it is the mechanism to end blackouts that produce so many damages and losses of billions of dollars to both generators and users of electrical service, throughout the world. [Spanish] Esta nueva mas alta tecnologia, 100% venezolana y unica en el mundo, innovacion tecnologica, patente mundial ofrece maxima proteccion, seguridad y riesgo cero (0) a todos los sistemas de generacion electrica: centrales hidroelectricas, termoelectricas, de viento, nucleares y solar, otros; es la unica tecnologia en el mundo que tiene el potencial para dispersar y propagar a la masa terrestre las enormes energias asociadas a las descargas atmosfericas (rayos) que estan en el orden de: 200.000 a 500.000 amperios, 1.000 millones de kilovatios y voltajes transitorios de alto nivel de 100 millones de voltios. Esta nueva alta tecnologia es la solucion al paradigma de Benjamin Franklin y es el mecanismo para eliminar apagones que producen danos y perdidas de billones de dolares para ambos: generados y usuarios del servicio electrico, alrededor del mundo.

Hoiatus Hansa aktsiale / Annika Matson, Romet Kreek

Index Scriptorium Estoniae

Matson, Annika, 1976-

2004-01-01

Hollandi pank ING andis kiirelt kallinenud Hansapanga aktsiale müügisoovituse. Diagramm. Lisa: Hansapanga aktsia on Tallinna börsi suunanäitaja; ING prognoosid Hansapanga kohta on seni üsna täppi läinud

Synthesis of 2-amino-4H-chromene derivatives under microwave ...

Indian Academy of Sciences (India)

ing method to construct the 2-amino-4H-chromene skeleton. 2. Experimental. 2.1 Materials and methods .... ing 2-amino-4H-chromene (3a–r) derivatives in good .... Students. Supplementary information. The electronic supporting information ...

Centrality measures for immunization of weighted networks

Directory of Open Access Journals (Sweden)

Mohammad Khansari

2016-03-01

Full Text Available Effective immunization of individual communities with minimal cost in vaccination has made great discussion surrounding the realm of complex networks. Meanwhile, proper realization of relationship among people in society and applying it to social networks brings about substantial improvements in immunization. Accordingly, weighted graph in which link weights represent the intensity and intimacy of relationships is an acceptable approach. In this work we employ weighted graphs and a wide variety of weighted centrality measures to distinguish important individuals in contagion of diseases. Furthermore, we propose new centrality measures for weighted networks. Our experimental results show that Radiality-Degree centrality is satisfying for weighted BA networks. Additionally, PageRank-Degree and Radiality-Degree centralities showmoreacceptable performance in targeted immunization of weighted networks.

BWR plant advanced central control panel PODIA

International Nuclear Information System (INIS)

Fujii, K.; Hayakawa, H.; Ikeda, Y.; Neda, T.; Suto, O.; Takamiya, S.

1983-01-01

BWR plant central control panels have become more and more enlarged and complicated recently due to the magnification of the scale of a plant and the requirement to reinforce safety. So, it is important to make communication between men and the complicated central control panel smooth. Toshiba has developed an advanced central control panel, named PODIA, which uses many computers and color CRTs, and PODIA is now in the stage of application to practical plants. In this article, the writers first touch upon control functions transition in the central control room, the PODIA position concerning the world-wide trend in this technology phase and the human engineering on the design. Then they present concrete design concepts for the control board and computer system which constitute PODIA

Central beta-adrenergic modulation of cognitive flexibility.

Science.gov (United States)

Beversdorf, David Q; White, Dawn M; Chever, Daquesha C; Hughes, John D; Bornstein, Robert A

2002-12-20

Situational stressors and anxiety impede performance on creativity tests requiring cognitive flexibility. Preliminary research revealed better performance on a task requiring cognitive flexibility, the anagram task, after propranolol (beta-adrenergic antagonist) than after ephedrine (beta-adrenergic agonist). However, propranolol and ephedrine have both peripheral and central beta-adrenergic effects. In order to determine whether noradrenergic modulation of cognitive flexibility is a centrally or peripherally mediated phenomenon, we compared the effects of propranolol (peripheral and central beta-blocker), nadolol (peripheral beta-blocker), and placebo on anagram task performance. Solution latency scores for each subject were compared across the drug conditions. Anagram solution latency scores after propranolol were significantly lower than after nadolol. This suggests a centrally mediated modulatory influence of the noradrenergic system on cognitive flexibility.

African Journals Online: Central African Republic

African Journals Online (AJOL)

African Journals Online: Central African Republic. Home > African Journals Online: Central African Republic. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Browse By Category · Browse Alphabetically · Browse By Country · List All Titles · Free to read Titles This ...

Central Sensitization-Based Classification for Temporomandibular Disorders: A Pathogenetic Hypothesis

Directory of Open Access Journals (Sweden)

Annalisa Monaco

2017-01-01

Full Text Available Dysregulation of Autonomic Nervous System (ANS and central pain pathways in temporomandibular disorders (TMD is a growing evidence. Authors include some forms of TMD among central sensitization syndromes (CSS, a group of pathologies characterized by central morphofunctional alterations. Central Sensitization Inventory (CSI is useful for clinical diagnosis. Clinical examination and CSI cannot identify the central site(s affected in these diseases. Ultralow frequency transcutaneous electrical nerve stimulation (ULFTENS is extensively used in TMD and in dental clinical practice, because of its effects on descending pain modulation pathways. The Diagnostic Criteria for TMD (DC/TMD are the most accurate tool for diagnosis and classification of TMD. However, it includes CSI to investigate central aspects of TMD. Preliminary data on sensory ULFTENS show it is a reliable tool for the study of central and autonomic pathways in TMD. An alternative classification based on the presence of Central Sensitization and on individual response to sensory ULFTENS is proposed. TMD may be classified into 4 groups: (a TMD with Central Sensitization ULFTENS Responders; (b TMD with Central Sensitization ULFTENS Nonresponders; (c TMD without Central Sensitization ULFTENS Responders; (d TMD without Central Sensitization ULFTENS Nonresponders. This pathogenic classification of TMD may help to differentiate therapy and aetiology.

Central depression of nuclear charge density distribution

International Nuclear Information System (INIS)

Chu Yanyun; Ren Zhongzhou; Wang Zaijun; Dong Tiekuang

2010-01-01

The center-depressed nuclear charge distributions are investigated with the parametrized distribution and the relativistic mean-field theory, and their corresponding charge form factors are worked out with the phase shift analysis method. The central depression of nuclear charge distribution of 46 Ar and 44 S is supported by the relativistic mean-field calculation. According to the calculation, the valence protons in 46 Ar and 44 S prefer to occupy the 1d 3/2 state rather than the 2s 1/2 state, which is different from that in the less neutron-rich argon and sulfur isotopes. As a result, the central proton densities of 46 Ar and 44 S are highly depressed, and so are their central charge densities. The charge form factors of some argon and sulfur isotopes are presented, and the minima of the charge form factors shift upward and inward when the central nuclear charge distributions are more depressed. Besides, the effect of the central depression on the charge form factors is studied with a parametrized distribution, when the root-mean-square charge radii remain constant.

47{sup th} Annual meeting on nuclear technology (AMNT 2016). Key Topic / Outstanding know-how and sustainable excellence. Workshop: Preserving competence in nuclear technology

Energy Technology Data Exchange (ETDEWEB)

Steinwarz, Wolfgang

2016-10-15

On the 18{sup th} workshop Preserving Competence in Nuclear Technology 24 young scientists presented the scientific results from their work covering a broad spectrum of technical areas. This demonstrated again the strong engagement of the younger generation as part of the German nuclear society. Prof.Dr.-Ing. Eckart Laurin, Prof.Dr.-Ing. Marco K. Koch, Dr. Katharina Stummeyer, and Dr.-Ing. Wolfgang Steinwarz as members of the jury assessed the written compacts and the oral presentations to award the Siempelkamp Competence Price 2016 to Andreas Wanninger from Technische Universitaet Muenchen.

47th Annual meeting on nuclear technology (AMNT 2016). Key Topic / Outstanding know-how and sustainable excellence. Workshop: Preserving competence in nuclear technology

International Nuclear Information System (INIS)

Steinwarz, Wolfgang

2016-01-01

On the 18 th workshop Preserving Competence in Nuclear Technology 24 young scientists presented the scientific results from their work covering a broad spectrum of technical areas. This demonstrated again the strong engagement of the younger generation as part of the German nuclear society. Prof.Dr.-Ing. Eckart Laurin, Prof.Dr.-Ing. Marco K. Koch, Dr. Katharina Stummeyer, and Dr.-Ing. Wolfgang Steinwarz as members of the jury assessed the written compacts and the oral presentations to award the Siempelkamp Competence Price 2016 to Andreas Wanninger from Technische Universitaet Muenchen.

Characterization and monitoring of selected rhizobial strains ...

African Journals Online (AJOL)

SERVER

2007-06-18

Jun 18, 2007 ... Fax: +66-44-216345. fixing symbiosis with bacteria known as rhizobia. ... Rhizobial strains were cultured on Yeast-Malt extract agar contain- ing bromthymol blue ... Colony form-ing was observed every day as well as the ...

Central Bank Independence and Inflation IN EU-28

Directory of Open Access Journals (Sweden)

Beju Daniela-Georgeta

2017-12-01

Full Text Available Today, both policymakers and academicians consider that the central bank’s main goal is to guarantee price stability. The central bank can sustain the government’s economic policies, but only without prejudicing this objective. In order to focus on price stability several studies found that central bank should have a high level of independence. This is why during the recent decades the majority of developed countries, but also several emerging economies have employed institutional reforms that conferred their monetary authorities – the central bank – more independence.

Ethnic Harassment, Ethnic Identity Centrality, and Well-Being.

Science.gov (United States)

Wolfram, Hans-Joachim; Linton, Kenisha; McDuff, Nona

2018-02-12

In this study, we examined the direct effect of (positive vs. negative) evaluation of potentially harassing experiences due to ethnic background on impaired well-being as well as the moderating effect of ethnic identity centrality on the relationship between (lower vs. higher) frequency of potentially harassing experiences and impaired well-being. Using a gender-balanced sample with equal proportions of black and minority ethnic and white undergraduate students (N = 240), we found that, expectedly, ethnic identity centrality intensified the effects of higher frequency of potentially harassing experiences on lower self-esteem and lower positive affect. Unexpectedly, however, gender identity centrality buffered the effects of higher frequency as well as more negative evaluation of potentially harassing experiences on lower self-esteem, indicating that gender identity centrality may be a protective resource, even though it is not specific to ethnic harassment. Exploratory analyses revealed that for black and minority ethnic respondents with high ethnic identity centrality and for white respondents with low ethnic identity centrality, there were associations between more negative evaluation of potentially harassing experiences and lower self-esteem and lower positive affect. This finding might indicate that ethnic identity centrality was a risk factor in black and ethnic minority respondents, but a protective factor in white respondents.

31 CFR 535.433 - Central Bank of Iran.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Central Bank of Iran. 535.433 Section 535.433 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... § 535.433 Central Bank of Iran. The Central Bank of Iran (Bank Markazi Iran) is an agency...

endodontic treatment of unusually long discolored maxillary central ...

African Journals Online (AJOL)

a few cases of dual–rooted maxillary central incisor have been reported in literature1-5. Maxillary central incisors vary in root ... The following case report describes the endodontic management of a patient with an unusually long maxillary central incisor in our environment. CASE PROFILE. A 31 year-old male was referred ...

GFT centrality: A new node importance measure for complex networks

Science.gov (United States)

Singh, Rahul; Chakraborty, Abhishek; Manoj, B. S.

2017-12-01

Identifying central nodes is very crucial to design efficient communication networks or to recognize key individuals of a social network. In this paper, we introduce Graph Fourier Transform Centrality (GFT-C), a metric that incorporates local as well as global characteristics of a node, to quantify the importance of a node in a complex network. GFT-C of a reference node in a network is estimated from the GFT coefficients derived from the importance signal of the reference node. Our study reveals the superiority of GFT-C over traditional centralities such as degree centrality, betweenness centrality, closeness centrality, eigenvector centrality, and Google PageRank centrality, in the context of various arbitrary and real-world networks with different degree-degree correlations.

<=ryptochromes and Biological Clocks -36 ...

Indian Academy of Sciences (India)

ing from cyanobacteria to humans to plants, and this high degree of ... ing them. The innate or free-running period of circardian rhythms (mea- sured in a ..... neutral radical to the catalytically competent FADH form. The enzyme then dissociates ...

Government-Sponsored Research and Development Efforts in the Area of Intelligent Tutoring Systems. Summary Report.

Science.gov (United States)

1995-02-01

skills using thecnntextof microeconomics . Students work- ing with Smithtown for 5 hours achieved the same gains as those in a classroom gruup which had...ing debrief Via associated workbooks Cognitive apprenticeship with teachers by alternating between diagnostic and training processes Progress

The central image of a gravitationally lensed quasar.

Science.gov (United States)

Winn, Joshua N; Rusin, David; Kochanek, Christopher S

2004-02-12

A galaxy can act as a gravitational lens, producing multiple images of a background object. Theory predicts that there should be an odd number of images produced by the lens, but hitherto almost all lensed objects have two or four images. The missing 'central' images, which should be faint and appear near the centre of the lensing galaxy, have long been sought as probes of galactic cores too distant to resolve with ordinary observations. There are five candidates for central images, but in one case the third image is not necessarily the central one, and in the others the putative central images might be foreground sources. Here we report a secure identification of a central image, based on radio observations of one of the candidates. Lens models using the central image reveal that the massive black hole at the centre of the lensing galaxy has a mass of 20,000M(o) pc(-2), which is in agreement with expections based on observations of galaxies that are much closer to the Earth.

Multifocal electroretinogram and central visual field testing in central areolar choroidal dystrophy.

Science.gov (United States)

Gundogan, Fatih Cakir; Dinç, Umut Asli; Erdem, Uzeyir; Ozge, Gokhan; Sobaci, Gungor

2010-01-01

To study multifocal electroretinogram (mfERG) and its relation to retinal sensitivity assessed by Humphrey visual field (HVF) analysis in central areolar choroidal dystrophy (CACD). Seven eyes of 4 patients with CACD and 15 normal control subjects were examined. mfERG and central 30/2 HVF were tested for each participant. Ring analysis in mfERG was evaluated. HVF results were evaluated in 5 concentric rings in order to compare the results to concentric ring analysis in mfERG. The differences between control subjects and patients were evaluated by Mann-Whitney U test and the correlations were assessed by Spearman test. Mean Snellen acuity was 0.49+/-0.10 in patients. HVF revealed central scotoma in 6 of 7 eyes (85.7%), whereas a paracentral scotoma extending to fixation point was detected in 1 eye. The retinal sensitivities in 5 concentric rings in HVF were significantly lower (p<0.001 for ring 1 to ring 4, and p=0.017 in ring 5) in CACD patients. Similarly, CACD patients had lower P1/N1 amplitudes (p<0.05) and delayed P1/N1 implicit times (p<0.05). In CACD, in the areas of scotoma detected by HVF, mfERG values were depressed. However, both mfERG and HVF abnormalities were found outside the areas of ophthalmoscopically normal retinal areas.

Central nervous system mesenchymal chondrosarcoma

Energy Technology Data Exchange (ETDEWEB)

Salvati, M.; Frati, A.; Piccirilli, M.; Agrillo, A.; Brogna, C.; Occhiogrosso, G.; Giangaspero, F. [INM Neuromed IRCCS, Pozzilli (Italy). Dept. of Neurosurgery; Caroli, E. [Policlinico S. Andrea, Rome (Italy). Dept. of Neurological Sciences, Neurosurgery

2005-06-15

Central nervous system mesenchymal chondrosarcomas are rare malignant tumors that constitute a separate entity from the classical chondrosarcoma and myxoid variant. Clinical behaviour of central nervous system chondrosarcomas is still unknown. We describe two rare examples of intracranial mesenchymal chondrosarcoma with a review of the literature, in an attempt to clarify the clinical characteristics, prognosis and treatment of choice of these unusual tumors. Among the 55 reported cases, 23 had postoperative radiotherapy. Although there is no statistical significance according to the Log-Rank test (p=0.7), the patients treated with radiation therapy seem to have a better chance of survival. Patients who had adjuvant chemotherapy (only 5) showed survival times similar to those patients who had none. Although clinical behaviour of central nervous system chondrosarcomas remains to be defined, data from our series as well as literature show that radical removal is the best therapeutic choice. In addition, patients treated with postoperative radiotherapy seem to show a trend toward increased survival.

Central nervous system mesenchymal chondrosarcoma

International Nuclear Information System (INIS)

Salvati, M.; Frati, A.; Piccirilli, M.; Agrillo, A.; Brogna, C.; Occhiogrosso, G.; Giangaspero, F.; Caroli, E.

2005-01-01

Central nervous system mesenchymal chondrosarcomas are rare malignant tumors that constitute a separate entity from the classical chondrosarcoma and myxoid variant. Clinical behaviour of central nervous system chondrosarcomas is still unknown. We describe two rare examples of intracranial mesenchymal chondrosarcoma with a review of the literature, in an attempt to clarify the clinical characteristics, prognosis and treatment of choice of these unusual tumors. Among the 55 reported cases, 23 had postoperative radiotherapy. Although there is no statistical significance according to the Log-Rank test (p=0.7), the patients treated with radiation therapy seem to have a better chance of survival. Patients who had adjuvant chemotherapy (only 5) showed survival times similar to those patients who had none. Although clinical behaviour of central nervous system chondrosarcomas remains to be defined, data from our series as well as literature show that radical removal is the best therapeutic choice. In addition, patients treated with postoperative radiotherapy seem to show a trend toward increased survival

Centralization and decentralization in energy systems and associated risks

International Nuclear Information System (INIS)

Rehm, W.; Schinner, F.; Kromp, W.

1998-01-01

Full text of publication follows: the concept of centralization/decentralization is - considering its widespread use - surprisingly ill-defined. Within the SERF-program (Socio Economic Research on Fusion) an attempt is made to clarify the complex issue of centralization/decentralization and to analyze its expected interaction with electricity production system in the case of nuclear fusion. Fusion research at the time is a multinational, highly centralized undertaking. As a result of this, and due to the expected large energy production units, it is generally expected that fusion will be embedded in a highly centralized, international energy supply system. The degree of centralization of an energy supply system, however, is believed to have for reaching consequences on the stability of the system, and beyond that, on decision making processes in energy policy, as well as democratic structures on the national or even international level. Internationalization might require control instruments that do not exist so far. Amongst other reservations, it is the possibly unwanted consequences of such a highly centralized, international energy supply system that limit acceptance of the fusion technology in the public. Therefore, centralization and decentralization trends of energy supply systems over the years are being looked at, to study their influence on the political and social systems (and vice-versa). In a first step, an attempt is made to classify centralization. Careful analyses and evaluation of available literature revealed a broad spectrum of different forms and degrees of centralization. Various parameters describing energy production and distribution are used. A differentiation of centralization on a technical and on an organizational level seems necessary, although they are not fully independent of each other. Beyond this, the choice of parameters must depend on the questions to be addressed. A new approach defining different levels and degrees of

Centralization and decentralization in energy systems and associated risks

Energy Technology Data Exchange (ETDEWEB)

Rehm, W.; Schinner, F.; Kromp, W. [Vienna Univ., Institute of Risk Research, IRR (Austria)

1998-07-01

Full text of publication follows: the concept of centralization/decentralization is - considering its widespread use - surprisingly ill-defined. Within the SERF-program (Socio Economic Research on Fusion) an attempt is made to clarify the complex issue of centralization/decentralization and to analyze its expected interaction with electricity production system in the case of nuclear fusion. Fusion research at the time is a multinational, highly centralized undertaking. As a result of this, and due to the expected large energy production units, it is generally expected that fusion will be embedded in a highly centralized, international energy supply system. The degree of centralization of an energy supply system, however, is believed to have for reaching consequences on the stability of the system, and beyond that, on decision making processes in energy policy, as well as democratic structures on the national or even international level. Internationalization might require control instruments that do not exist so far. Amongst other reservations, it is the possibly unwanted consequences of such a highly centralized, international energy supply system that limit acceptance of the fusion technology in the public. Therefore, centralization and decentralization trends of energy supply systems over the years are being looked at, to study their influence on the political and social systems (and vice-versa). In a first step, an attempt is made to classify centralization. Careful analyses and evaluation of available literature revealed a broad spectrum of different forms and degrees of centralization. Various parameters describing energy production and distribution are used. A differentiation of centralization on a technical and on an organizational level seems necessary, although they are not fully independent of each other. Beyond this, the choice of parameters must depend on the questions to be addressed. A new approach defining different levels and degrees of

Central American Climatology

Science.gov (United States)

1985-04-01

Central America, as where mean temperatures are relatively warm throughout the year de- so spite seasonal rainfall changes. 75 Elevation, solar angle...November 1982 Control Hidalgo Anos.1952-1963, Republica de Nicaragua, Ministerio de Formento Y O0.PP, Comision Nacional de Energia . Craig, Richard A., The

3D CENTRAL LINE EXTRACTION OF FOSSIL OYSTER SHELLS

Directory of Open Access Journals (Sweden)

A. Djuricic

2016-06-01

Full Text Available Photogrammetry provides a powerful tool to digitally document protected, inaccessible, and rare fossils. This saves manpower in relation to current documentation practice and makes the fragile specimens more available for paleontological analysis and public education. In this study, high resolution orthophoto (0.5 mm and digital surface models (1 mm are used to define fossil boundaries that are then used as an input to automatically extract fossil length information via central lines. In general, central lines are widely used in geosciences as they ease observation, monitoring and evaluation of object dimensions. Here, the 3D central lines are used in a novel paleontological context to study fossilized oyster shells with photogrammetric and LiDAR-obtained 3D point cloud data. 3D central lines of 1121 Crassostrea gryphoides oysters of various shapes and sizes were computed in the study. Central line calculation included: i Delaunay triangulation between the fossil shell boundary points and formation of the Voronoi diagram; ii extraction of Voronoi vertices and construction of a connected graph tree from them; iii reduction of the graph to the longest possible central line via Dijkstra’s algorithm; iv extension of longest central line to the shell boundary and smoothing by an adjustment of cubic spline curve; and v integration of the central line into the corresponding 3D point cloud. The resulting longest path estimate for the 3D central line is a size parameter that can be applied in oyster shell age determination both in paleontological and biological applications. Our investigation evaluates ability and performance of the central line method to measure shell sizes accurately by comparing automatically extracted central lines with manually collected reference data used in paleontological analysis. Our results show that the automatically obtained central line length overestimated the manually collected reference by 1.5% in the test set, which

Central obscuration effects on optical synthetic aperture imaging

Science.gov (United States)

Wang, Xue-wen; Luo, Xiao; Zheng, Li-gong; Zhang, Xue-jun

2014-02-01

Due to the central obscuration problem exists in most optical synthetic aperture systems, it is necessary to analyze its effects on their image performance. Based on the incoherent diffraction limited imaging theory, a Golay-3 type synthetic aperture system was used to study the central obscuration effects on the point spread function (PSF) and the modulation transfer function (MTF). It was found that the central obscuration does not affect the width of the central peak of the PSF and the cutoff spatial frequency of the MTF, but attenuate the first sidelobe of the PSF and the midfrequency of the MTF. The imaging simulation of a Golay-3 type synthetic aperture system with central obscuration proved this conclusion. At last, a Wiener Filter restoration algorithm was used to restore the image of this system, the images were obviously better.

Research on centrality of urban transport network nodes

Science.gov (United States)

Wang, Kui; Fu, Xiufen

2017-05-01

Based on the actual data of urban transport in Guangzhou, 19,150 bus stations in Guangzhou (as of 2014) are selected as nodes. Based on the theory of complex network, the network model of Guangzhou urban transport is constructed. By analyzing the degree centrality index, betweenness centrality index and closeness centrality index of nodes in the network, the level of centrality of each node in the network is studied. From a different point of view to determine the hub node of Guangzhou urban transport network, corresponding to the city's key sites and major transfer sites. The reliability of the network is determined by the stability of some key nodes (transport hub station). The research of network node centralization can provide a theoretical basis for the rational allocation of urban transport network sites and public transport system planning.

Russian Language in the Central Asia Region

Directory of Open Access Journals (Sweden)

Ksenia Petrovna Borishpolets

2014-01-01

Full Text Available He article is devoted to the role of the Russian language in Central Asia and its development perspectives in the context of the Eurasian integration processes. Russian language has a long historical tradition in Central Asia and hasn't lost its importance even at the background of two waves of "derussification" that took place after 1991. Notwithstanding the decrease of the status, it keeps substantial public significance. During last two decades only in Turkmenistan we are witnessing the decrease in spreading of the Russian language among title population of the Central Asia region. Its positions as an active communication channel is secured not only by the social tradition, but also by the competitiveness of the Russian language education, advantages of the bilingual business, requirements of the labor migrants, HR interests and by some other pragmatic thoughts, which role within the context of Eurasian economic integration will increase. Despite the difficulties, it is too early to speak about the decrease of the Russian language in the Central Asia region. It is more likely that the institutes itself that maintain it and promoting it are at the low ebb. New scales and forms of practical work that is interested not only for Russia, but also Central Asia countries are required. Pressure on the resources of the Russian language increases the possibility of ethnic conflicts and strengthens the positions of political radicalism in Central Asia region.

Central alarm system replacement in NPP Krsko

International Nuclear Information System (INIS)

Cicvaric, D.; Susnic, M.; Djetelic, N.

2004-01-01

Current NPP Krsko central alarm system consists of three main segments. Main Control Board alarm system (BETA 1000), Ventilation Control Board alarm system (BETA 1000) and Electrical Control Board alarm system (BETA 1100). All sections are equipped with specific BetaTone audible alarms and silence, acknowledge as well as test push buttons. The main reason for central alarm system replacement is system obsolescence and problems with maintenance, due to lack of spare parts. Other issue is lack of system redundancy, which could lead to loss of several Alarm Light Boxes in the event of particular power supply failure. Current central alarm system does not provide means of alarm optimization, grouping or prioritization. There are three main options for central alarm system replacement: Conventional annunciator system, hybrid annunciator system and advanced alarm system. Advanced alarm system implementation requires Main Control Board upgrade, integration of process instrumentation and plant process computer as well as long time for replacement. NPP Krsko has decided to implement hybrid alarm system with patchwork approach. The new central alarm system will be stand alone, digital, with advanced filtering and alarm grouping options. Sequence of event recorder will be linked with plant process computer and time synchronized with redundant GPS signal. Advanced functions such as link to plant procedures will be implemented with plant process computer upgrade in outage 2006. Central alarm system replacement is due in outage 2004.(author)

Central Hemodynamics and Microcirculation in Critical Conditions

Directory of Open Access Journals (Sweden)

A. A. Kosovskikh

2013-01-01

Full Text Available Objective: to compare central hemodynamic and microcirculatory changes in critical conditions caused by different factors and to reveal their possible differences for a further differentiated approach to intensive therapy. Subjects and methods. The study covered 16 subjects with severe concomitant injury (mean age 41.96±2.83 years and 19 patients with general purulent peritonitis (mean age 45.34±2.16 years. Their follow-up was 7 days. The central hemodynamics was estimated by transpulmonary thermodilution using a Pulsion PiCCO Plus system (Pulsion Medical Systems, Germany. The microcirculatory bed was evaluated by cutaneous laser Doppler flowmetry using a LAKK-02 capillary blood flow laser analyzer (LAZMA Research-and-Production Association, Russian Federation. Results. The pattern of central hemodynamic and microcirculatory disorders varies with the trigger that has led to a critical condition. Central hemodynamics should be stabilized to ensure the average level of tissue perfusion in victims with severe concomitant injury. In general purulent peritonitis, microcirculatory disorders may persist even if the macrohemodynamic parameters are normal. Conclusion. The macrohemodynamic and microcirculatory differences obtained during the study suggest that a complex of intensive therapy should be differentiated and, if the latter is used, it is necessary not only to be based on the central hemodynamics, but also to take into consideration functional changes in microcirculation. Key words: severe concomitant injury, general purulent peritonitis, micro-circulation, central hemodynamics, type of circulation.

Central Neuropathic Pain in Spinal Cord Injury

Science.gov (United States)

Lee, Sujin; Zhao, Xing; Hatch, Maya; Chun, Sophia; Chang, Eric

2015-01-01

Spinal cord injury (SCI) is a devastating medical condition affecting 1.2 million people in the United States. Central neuropathic pain is one of the most common medical complications of SCI. Current treatment options include opioids, antiepileptic agents such as gabapentin, antispastic agents such as baclofen or tizanidine, and tricyclic acid. Other options include complementary, nonpharmacological treatment such as exercise or acupuncture, interventional treatments, and psychological approaches. Although these treatment options exist, central neuropathic pain in patients with SCI is still extremely difficult to treat because of its complexity. To develop and provide more effective treatment options to these patients, proper assessment of and classification tools for central neuropathic pain, as well as a better understanding of the pathophysiology, are needed. A combination of approaches, from standard general pain assessments to medically specific questions unique to SCI pathophysiology, is essential for this population. A multidisciplinary approach to patient care, in addition with a better understanding of pathophysiology and diagnosis, will lead to improved management and treatment of patients with SCI displaying central neuropathic pain. Here we summarize the most recent classification tools, pathophysiology, and current treatment options for patients with SCI with central neuropathic pain. PMID:25750485

Vantage point.

Science.gov (United States)

Kay, Jenny

2004-06-01

'Management by expletives' sums up the new Channel 4 programme, Ramsay's Kitchen Nightmares, in which TV chef Gordon Ramsay attempts to turn around a series of failing kitchens. 'It's your f***ing kitchen,' Ramsay tells one hapless head chef, 'F***ing organise it.'

76 FR 20039 - The Medicine Dropper; Revocation of Registration

Science.gov (United States)

2011-04-11

..., Respondent has repeatedly violated the terms of the Settlement Agreement'' by ``permitt[ing] doctor shopping, fill[ing] prescriptions for controlled substances without a legitimate medical purpose,'' and violating... intended to resolve the latter's civil and administrative claims based on its contentions that, between...

MANAGEMENT OF CHILDREN WITH CEREBRAL PALSY

African Journals Online (AJOL)

Enrique

ing children with cerbral palsy spans more than 4 decades, and has inspired so many of us to work in .... toy. Prone lying over a longitudinal pillow with weight bearing on the forearms should alternate .... ing being blind and deaf. Assessing a.

Joint Force Quarterly. Issue 39

Science.gov (United States)

2005-10-01

development of countermeasures to disrupt terrorist activities and focus- ing information collection on al Qaeda financing and network operatives...aircraft, provid- ing an hour of coverage each over the assault area. The British carrier-based Seafires operating from HMS Unicorn , Battler, Attacker

Co-occurring Conditions Toolkit: Mild Traumatic Brain Injury and Psychological Health

Science.gov (United States)

2009-01-01

diarrhea, vomit- ing, abdominal pain, polyuria and polydipsia yy Normal fluid and salt intake must be maintained during therapy yy Half life...weak- ness, tremor, headache, hand tremor, nausea, diarrhea, vomit- ing, abdominal pain, polyuria and polydipsia yy Normal fluid and salt intake

Groundwater availability of the Central Valley Aquifer, California

Science.gov (United States)

Faunt, Claudia C.

2009-01-01

California's Central Valley covers about 20,000 square miles and is one of the most productive agricultural regions in the world. More than 250 different crops are grown in the Central Valley with an estimated value of $17 billion per year. This irrigated agriculture relies heavily on surface-water diversions and groundwater pumpage. Approximately one-sixth of the Nation's irrigated land is in the Central Valley, and about one-fifth of the Nation's groundwater demand is supplied from its aquifers. The Central Valley also is rapidly becoming an important area for California's expanding urban population. Since 1980, the population of the Central Valley has nearly doubled from 2 million to 3.8 million people. The Census Bureau projects that the Central Valley's population will increase to 6 million people by 2020. This surge in population has increased the competition for water resources within the Central Valley and statewide, which likely will be exacerbated by anticipated reductions in deliveries of Colorado River water to southern California. In response to this competition for water, a number of water-related issues have gained prominence: conservation of agricultural land, conjunctive use, artificial recharge, hydrologic implications of land-use change, and effects of climate variability. To provide information to stakeholders addressing these issues, the USGS Groundwater Resources Program made a detailed assessment of groundwater availability of the Central Valley aquifer system, that includes: (1) the present status of groundwater resources; (2) how these resources have changed over time; and (3) tools to assess system responses to stresses from future human uses and climate variability and change. This effort builds on previous investigations, such as the USGS Central Valley Regional Aquifer System and Analysis (CV-RASA) project and several other groundwater studies in the Valley completed by Federal, State and local agencies at differing scales. The

through Slicing, DryIng and Packagi.

African Journals Online (AJOL)

plastic containers and storedjor nine monthl:. with observation 'carried in ... high value sugars for domestic consumption, in- house at ambient conditions in ... Availability of sweet potato roots is very sea- Shinyanga town in Tanzania in the ...

All aboard the Safety Train(ing)!

CERN Multimedia

Rosaria Marraffino

2015-01-01

Would you like to influence CERN’s safety courses? Do you want to help build better training courses? If your answer is yes to one or both of these questions: now is the time! The Safety Training section is looking for volunteers from the whole CERN community to test new courses before they go online for all members of the personnel.    The Safety Training section is redesigning the CERN e-learning package in order to adopt a more educational approach and to make the courses a more enjoyable experience. The section is now calling for volunteers. “We know we can do much more with testers’ help and feedback,” explains Christoph Balle, Safety Training section leader. “By having the end users actively involved in the process, we’ll achieve our goal of communicating safety in the best possible way. As the volunteers will play an active role in the development of the courses, they will be providing a service to the whole community.&am...

Idea juht eitas maksupettust / Inge Rumessen

Index Scriptorium Estoniae

Rumessen, Inge

2002-01-01

Reklaamiagentuuri Idea juht Mark Eikner eitas kohtuistungil seost mitmemiljonilise maksupettuse skeemiga möödunud kohalike valimiste ajal. Kohtuprotsess Meelis Siidirätsepa üle, kes OÜ Rescue juhina jättis tasumata 1,5 milj. krooni käibemaksu

Drypac-ing waste away at Sellafield

International Nuclear Information System (INIS)

Anon.

1997-01-01

The Sellafield Drypac Plant (SDP) is designed to treat intermediate level wastes stored on the Sellafield site in the UK. SDP is a key component in the overall strategy of encapsulating ILW for future disposal in an underground repository. Civil work on the plant has started and it is scheduled to begin active operations in 2002. (UK)

SIP-ing the elixir of youth.

Science.gov (United States)

Mair, William; Steffen, Kristan K; Dillin, Andrew

2011-09-16

AMP-activated protein kinase (AMPK) is a conserved cellular fuel gauge previously implicated in aging. In this issue, Lu et al. (2011) describe how age-related deacetylation of Sip2, a subunit of the AMPK homolog in yeast, acts as a life span clock that can be wound backward or forward to modulate longevity. Copyright © 2011 Elsevier Inc. All rights reserved.

Muinasjutt köideteks / Inge Teder

Index Scriptorium Estoniae

Teder, Inge, 1931-

2005-01-01

Rahvusvahelisest köitekunsti näitusest ""Scripta manent III" Eesti Tarbekunsti- ja Disainimuuseumis. Raamatust "Maailma parim asi", mis sisaldab eesti laste kirjutatud muinasjutte. Pikemalt Kaire Oldi, Külli Grünbach-Seina ja Jaana Päeva töödest

Ravimid, risk, raha & tervis / Inge Pitsner

Index Scriptorium Estoniae

Pitsner, Inge

2008-01-01

Ravimifirma Roche Eesti OÜ tegevjuht Kadri Mägi selgitab ravimiäri toimemehhanisme ning põhjuseid, miks ravimitööstus on riskantne ja kallis valdkond. Lisa: Mis on farmakoökonoomika?; Roche Eesti kontor

TRACE-ing human trafficking : Project Findings

NARCIS (Netherlands)

Rijken, Conny; Pijnenburg, Annick

2016-01-01

Human trafficking is one of the largest criminal enterprises in the world. It is a multi-billion-dollar crime of global scale. This is because human trafficking as a criminal enterprise continues to evolve as a high profit-low risk business for perpetrators and challenges policy makers, law

Centralized rehabilitation after servere traumatic brain injury

DEFF Research Database (Denmark)

Engberg, Aase Worså; Liebach, Annette; Nordenbo, Annette Mosbæk

2006-01-01

OBJECTIVES: To present results from the first 3 years of centralized subacute rehabilitation after very severe traumatic brain injury (TBI), and to compare results of centralized versus decentralized rehabilitation. MATERIAL AND METHODS: Prospectively, the most severely injured group of adults from...... post-trauma was 0.29, and at 1 year 0.055 per 100,000 population. By comparison of 39 patients from the centralized unit injured in 2000-2003 with 21 patients injured in 1982, 1987 or 1992 and with similar PTA- and age distributions and male/female ratio, Glasgow Outcome Scale score at discharge...

Linfoma no-Hodgkin del sistema nervioso central

OpenAIRE

Iglesias Rozas, José Rafael, 1942-

2000-01-01

Diecisiete imágenes de un linfoma no-Hodgkin del sistema nervioso central en una paciente de 66 años. Seventeen pictures of a non-Hodgkin lymphoma of the central nervous system in a 66-year-old female patient.

Centralized rehabilitation after servere traumatic brain injury

DEFF Research Database (Denmark)

Engberg, Aase Worså; Liebach, Annette; Nordenbo, Annette Mosbæk

2006-01-01

OBJECTIVES: To present results from the first 3 years of centralized subacute rehabilitation after very severe traumatic brain injury (TBI), and to compare results of centralized versus decentralized rehabilitation. MATERIAL AND METHODS: Prospectively, the most severely injured group of adults fr...

The Cartan Matrix of a Centralizer Algebra

Indian Academy of Sciences (India)

2010-12-20

Dec 20, 2010 ... The centralizer algebra of a matrix consists of those matrices that commute with it. We investigate the basic representation-theoretic invariants of centralizer algebras, namely their radicals, projective indecomposable modules, injective indecomposable modules, simple modules and Cartan matrices.

Parallel Algorithm for Incremental Betweenness Centrality on Large Graphs

KAUST Repository

Jamour, Fuad Tarek

2017-10-17

Betweenness centrality quantifies the importance of nodes in a graph in many applications, including network analysis, community detection and identification of influential users. Typically, graphs in such applications evolve over time. Thus, the computation of betweenness centrality should be performed incrementally. This is challenging because updating even a single edge may trigger the computation of all-pairs shortest paths in the entire graph. Existing approaches cannot scale to large graphs: they either require excessive memory (i.e., quadratic to the size of the input graph) or perform unnecessary computations rendering them prohibitively slow. We propose iCentral; a novel incremental algorithm for computing betweenness centrality in evolving graphs. We decompose the graph into biconnected components and prove that processing can be localized within the affected components. iCentral is the first algorithm to support incremental betweeness centrality computation within a graph component. This is done efficiently, in linear space; consequently, iCentral scales to large graphs. We demonstrate with real datasets that the serial implementation of iCentral is up to 3.7 times faster than existing serial methods. Our parallel implementation that scales to large graphs, is an order of magnitude faster than the state-of-the-art parallel algorithm, while using an order of magnitude less computational resources.

Social network analysis using k-Path centrality method

Science.gov (United States)

Taniarza, Natya; Adiwijaya; Maharani, Warih

2018-03-01

k-Path centrality is deemed as one of the effective methods to be applied in centrality measurement in which the influential node is estimated as the node that is being passed by information path frequently. Regarding this, k-Path centrality has been employed in the analysis of this paper specifically by adapting random-algorithm approach in order to: (1) determine the influential user’s ranking in a social media Twitter; and (2) ascertain the influence of parameter α in the numeration of k-Path centrality. According to the analysis, the findings showed that the method of k-Path centrality with random-algorithm approach can be used to determine user’s ranking which influences in the dissemination of information in Twitter. Furthermore, the findings also showed that parameter α influenced the duration and the ranking results: the less the α value, the longer the duration, yet the ranking results were more stable.

Encouraging Diversity- and Representation-Awareness in Geographically Centralized Content

OpenAIRE

Graells-Garrido, Eduardo; Lalmas, Mounia; Baeza-Yates, Ricardo

2015-01-01

In centralized countries, not only population, media and economic power are concentrated, but people give more attention to central locations. While this is not inherently bad, this behavior extends to micro-blogging platforms: central locations get more attention in terms of information flow. In this paper we study the effects of an information filtering algorithm that decentralizes content in such platforms. Particularly, we find that users from non-central locations were not able to identi...

Investigating for failure of central ventilation fan blade

International Nuclear Information System (INIS)

Koo, Jae Raeyang; Ko Woo Sig; Kim, Yeon Hwan; Park, Kwang Ha

2002-01-01

During the operation, central ventilation fan stopped when switch 'on' condition. When central ventilation fan disassemble, ten blades of fan fractured. We have searched cause of failure. We had modeling one of the fan blades and analysis with computer programs. Thus we have find that fracture of central ventilation fan blades is alternative stress and vibration at hub. In this paper, we have described cause of failure

Non-linear realizations of supersymmetry with off-shell central charges

International Nuclear Information System (INIS)

Santos Filho, P.B.; Oliveira Rivelles, V. de.

1985-01-01

A new class of non-linear realizations of the extended supersymmetry algebra with central charges is presented. They were obtained by applying the technique of dimensional reduction by Legendre transformation to a non-linear realization without central charges in one higher dimension. As a result an off-shell central charge is obtained. The non-linear lagrangian is the same as is the case of vanishing central charge. On-shell the central charge vanishes so this non-linear realization differs from that without central charges only off-shell. It is worked in two dimensions and its extension to higher dimensions is discussed. (Author) [pt

Central Odontogenic Fibroma of Simple Type

Directory of Open Access Journals (Sweden)

Prasanth Thankappan

2014-01-01

Full Text Available Central odontogenic fibroma (COF is an extremely rare benign tumor that accounts for 0.1% of all odontogenic tumors. It is a lesion associated with the crown of an unerupted tooth resembling dentigerous cyst. In this report, a 10-year-old male patient is presented, who was diagnosed with central odontogenic fibroma of simple type from clinical, radiological, and histopathological findings.

Air and Space Power Journal. Volume 18, Number 1, Spring 2004

Science.gov (United States)

2004-01-01

entail mesh­ ing traditional synthetic polymer synthesis and processing with biochemistry and molecular change in temperature biology and then... dinosaurs of another technology and business era? Although some of these arguments may have merit, the fact remains that the world is becom­ ing

Hansapanga aktsia vastu ostuhuvi raugenud / Annika Matson

Index Scriptorium Estoniae

Matson, Annika, 1976-

2004-01-01

Analüütikud soovitavad Hansapanga aktsiat ostmise asemel hoida. Graafikud: Kümnekordne võit; Aktsia hind järgib ING soovitusi. Vt. samas: ING on seni oma prognoosidega Hansapanga aktsia trendi loonud. Raivo Sormunen. Hansapanga aktsia on julgest investeerijast teinud miljonäri;

Topical corticosteroid has no influence on inflammation or efficacy after ingenol mebutate treatment of grade i to III actinic keratoses (AK)

DEFF Research Database (Denmark)

Erlendsson, Andrés Már; Karmisholt, Katrine Elisabeth; Skovbølling Haak, Christina

2016-01-01

Background Ingenol mebutate (IngMeb) is approved for treatment of actinic keratoses (AK) and may cause unpredictable local skin responses (LSR). Objectives We sought to investigate whether IngMeb-induced LSR, pain, and pruritus could be alleviated with a topical glucocorticoid and, further, to as...

The Trade Off Between Central Bank Independence and Conservativeness

NARCIS (Netherlands)

Eijffinger, S.C.W.; Hoeberichts, M.M.

1996-01-01

This paper introduces a parameter for central bank independence in a monetary policy game with a conservative central banker.It tries to explain the optimal degree of central bank independence and conservativeness by four economic and political determinants, both theoretically and empirically.There

7 CFR 1032.2 - Central marketing area.

Science.gov (United States)

2010-01-01

... 7 Agriculture 9 2010-01-01 2009-01-01 true Central marketing area. 1032.2 Section 1032.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE MILK IN THE CENTRAL MARKETING AREA Order Regulating...

Central nervous system depressant activityof Leonurus sibiricus ...

African Journals Online (AJOL)

The methanol extract of aerial parts of Leonurus sibiricus was shown to possess central nervous system depressant action by significantly decreased the time of onset of sleep and potentiated the pentobarbital induced sleeping time in mice. Keywords: Leonurus sibiricus, labiatae, central nervous depressant, sedation

Concept of the central clip

DEFF Research Database (Denmark)

Alegria-Barrero, Eduardo; Chan, Pak Hei; Foin, Nicolas

2014-01-01

AIMS: Percutaneous edge-to-edge mitral valve repair with the MitraClip(®) was shown to be a safe and feasible alternative compared to conventional surgical mitral valve repair. We analyse the concept of the central clip and the predictors for the need of more than one MitraClip(®) in our high.......8±10.7 years (30 males, 13 females; mean logistic EuroSCORE 24.1±11, mean LVEF 47.5±18.5%; mean±SD) were treated. Median follow-up was 385 days (104-630; Q1-Q3). Device implantation success was 93%. All patients were treated following the central clip concept: 52.5% of MR was degenerative in aetiology and 47....... The presence of a restricted posterior mitral valve leaflet (PML) was inversely correlated with the need for more than one clip (p=0.02). A cut-off value of ≥7.5 mm for vena contracta predicted the need for a second clip (sensitivity 83%, specificity 90%, p=0.01). CONCLUSIONS: The central MitraClip(®) concept...

Central Venous Occlusion in the Hemodialysis Patient.

Science.gov (United States)

Krishna, Vinay Narasimha; Eason, Joseph B; Allon, Michael

2016-11-01

Central venous stenosis (CVS) is encountered frequently among hemodialysis patients. Prior ipsilateral central venous catheterization and cardiac rhythm device insertions are common risk factors, but CVS can also occur in the absence of this history. Chronic CVS can cause thrombosis with partial or complete occlusion of the central vein at the site of stenosis. CVS is frequently asymptomatic and identified as an incidental finding during imaging studies. Symptomatic CVS presents most commonly as an upper- or lower-extremity edema ipsilateral to the CVS. Previously unsuspected CVS may become symptomatic after placement of an ipsilateral vascular access. The likelihood of symptomatic CVS may be affected by the central venous catheter (CVC) location; CVC side; duration of CVC dependence; type, location, and blood flow of the ipsilateral access; and extent of collateral veins. Venous angiography is the gold standard for diagnosis. Percutaneous transluminal angioplasty and stent placement can improve the stenosis and alleviate symptoms, but CVS typically recurs frequently, requiring repeated interventions. Refractory symptomatic CVS may require ligation of the ipsilateral vascular access. Because no available treatment option is curative, the goal should be to prevent CVS by minimizing catheters and central vein instrumentation in patients with chronic kidney disease and dialysis patients. Copyright © 2016 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

Estrogen- and progesterone-receptor status in ECOG 2197: comparison of immunohistochemistry by local and central laboratories and quantitative reverse transcription polymerase chain reaction by central laboratory.

Science.gov (United States)

Badve, Sunil S; Baehner, Frederick L; Gray, Robert P; Childs, Barrett H; Maddala, Tara; Liu, Mei-Lan; Rowley, Steve C; Shak, Steven; Perez, Edith A; Perez, Edith D; Shulman, Lawrence J; Martino, Silvana; Davidson, Nancy E; Sledge, George W; Goldstein, Lori J; Sparano, Joseph A

2008-05-20

Central and local laboratory concordance for hormone receptor measurement is therapeutically important. This study compares estrogen receptor (ER) and progesterone receptor (PR) measured by local laboratory immunohistochemistry (IHC), central IHC, and central reverse-transcriptase polymerase chain reaction (RT-PCR) using a proprietary 21-gene assay. A case-control sample of 776 breast cancer patients from Eastern Cooperative Oncology Group (ECOG) study E2197 was evaluated. Central IHC Allred score for ER and PR was obtained using tissue microarrays and 1D5 ER antibody and 636 PR antibody. Quantitative RT-PCR for ER and PR in whole sections was performed using the 21-gene assay. For ER, the concordance between local and central IHC was 90% (95% CI, 88% to 92%), between local IHC and central RT-PCR was 91% (95% CI, 89% to 93%), and between central IHC and central RT-PCR was 93% (95% CI, 91% to 95%). For PR, the concordance between local IHC and central IHC was 84% (95% CI, 82% to 87%), between local IHC and central RT-PCR was 88% (95% CI, 85% to 90%), and between central IHC and central RT-PCR was 90% (95% CI, 88% to 92%). Although concordance was high, IHC ER-negative cases that were RT-PCR positive were more common than IHC ER-positive cases that were RT-PCR negative. In ER-positive patients, ER expression by central IHC Allred score was marginally associated with recurrence (P = .091), and ER expression by central RT-PCR was significantly associated with recurrence (P = .014). However, recurrence score, which incorporates additional genes/pathways, was a highly significant predictor of recurrence (P < .0001). There is a high degree of concordance among local IHC, central IHC, and central RT-PCR by the proprietary gene assay for ER and PR status. Although ER expression is marginally associated with relapse in ER-positive patients treated with chemohormonal therapy, recurrence score is a highly significant predictor of recurrence.

Heterogeneity across emerging market central bank reaction functions

Directory of Open Access Journals (Sweden)

Mesut Turkay

2017-09-01

Full Text Available The purpose of this study is to analyze monetary policy reaction functions of inflation targeting emerging market economies. Heterogeneity across central bank behavior is modelled using dynamic common correlated effects estimator in a panel data framework of 15 countries. The empirical method allows us to obtain country specific coefficients and shows differences across central bank reaction functions. Model results imply that central banks behave according to an extended Taylor rule and respond to deviation of inflation from the target, output gap, real exchange rate and external financial conditions. The study finds that emerging market central banks consider not only price stability, but also financial stability in setting of interest rates.

International Regulation of Central Arctic Ocean Fisheries

NARCIS (Netherlands)

Molenaar, E.J.

Due in particular to the impacts of climate change, the adequacy of the international regulation of Central Arctic Ocean fisheries has come under increasing scrutiny in recent years. As shown in this article, however, international regulation of Central Arctic Ocean fisheries is by no means entirely

Genetics Home Reference: congenital central hypoventilation syndrome

Science.gov (United States)

... Kravis EM, Zhou L, Rand CM, Weese-Mayer DE. Congenital central hypoventilation syndrome: PHOX2B mutations and phenotype. Am J Respir Crit ... BA, Leurgans SE, Berry-Kravis EM, Weese-Mayer DE. Congenital central hypoventilation syndrome: PHOX2B genotype determines risk for sudden death. Pediatr ...

Central Hardwoods ecosystem vulnerability assessment and synthesis: a report from the Central Hardwoods Climate Change Response Framework project

Science.gov (United States)

Leslie Brandt; Hong He; Louis Iverson; Frank R. Thompson; Patricia Butler; Stephen Handler; Maria Janowiak; P. Danielle Shannon; Chris Swanston; Matthew Albrecht; Richard Blume-Weaver; Paul Deizman; John DePuy; William D. Dijak; Gary Dinkel; Songlin Fei; D. Todd Jones-Farrand; Michael Leahy; Stephen Matthews; Paul Nelson; Brad Oberle; Judi Perez; Matthew Peters; Anantha Prasad; Jeffrey E. Schneiderman; John Shuey; Adam B. Smith; Charles Studyvin; John M. Tirpak; Jeffery W. Walk; Wen J. Wang; Laura Watts; Dale Weigel; Steve. Westin

2014-01-01

The forests in the Central Hardwoods Region will be affected directly and indirectly by a changing climate over the next 100 years. This assessment evaluates the vulnerability of terrestrial ecosystems in the Central Hardwoods Region of Illinois, Indiana, and Missouri to a range of future climates. Information on current forest conditions, observed climate trends,...

Proteomic landscape in Central and Eastern Europe: the 9th Central and Eastern European Proteomic Conference, Poznan, Poland

Czech Academy of Sciences Publication Activity Database

Gadher, S. J.; Marczak, L.; Luczak, M.; Stobiecki, M.; Widlak, P.; Kovářová, Hana

2016-01-01

Roč. 13, č. 1 (2016), s. 5-7 ISSN 1478-9450. [Central and Eastern European Proteomic Conference (CEEPC) /9./. Poznaň, 15.06.2015-18.06.2015] Institutional support: RVO:67985904 Keywords : Central and Eastern Proteomic Conference * proteomics * mass spectrometry imaging Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 3.849, year: 2016

Can the European Central Bank Create a European identity?

DEFF Research Database (Denmark)

Ravn Sørensen, Anders

2014-01-01

In what ways do central banks construct community, and how may the European Central Bank (ECB) contribute to a supranational European identity? In this paper I seek to answer these two questions by developing a conceptual framework for the ways that central banks construct national identities and...

Contested Communication; A Critical Analysis of Central Bank Speech

NARCIS (Netherlands)

L.H.J. Noordegraaf-Eelens (Liesbeth)

2010-01-01

textabstractThe more important words become, the more difficult it is to say things. This is the central message of this study on the communication by central bank presidents. Since the end of the twentieth century, central bank presidents see communication as an important means to influence

Central Asian Republic Info

Data.gov (United States)

US Agency for International Development — CAR Info is designed and managed by the Central Asian Republic Mission to fill in the knowledge and reporting gaps in existing agency systems for that Mission. It...

Topical Meeting on Optical Bistability Held at Rochester, New York on 15-17 June 1983.

Science.gov (United States)

1983-01-01

ThB16-1 SELF-BEATING INSTABILITIES IN BISTABLE DEVICES J.A. MARTIN-PEREDA .. M.A. MURIEL DEPARTAMENTO DE ELECTRONICA CUANTICA E.T.S. ING...OPTICAL BISTABLL SYSTEMS J.A. MARTIN PEREDA M.A. MURIEL ; DEPARTAMENIO DE ELECTRONICA CUANTICA E.T.S. ING. TELLCOMUNICACION UNIVERSIDAD POLITECNICA DE

Divergent Roles of Central Serotonin in Adult Hippocampal Neurogenesis

Directory of Open Access Journals (Sweden)

Ning-Ning Song

2017-06-01

Full Text Available The central serotonin (5-HT system is the main target of selective serotonin reuptake inhibitors (SSRIs, the first-line antidepressants widely used in current general practice. One of the prominent features of chronic SSRI treatment in rodents is the enhanced adult neurogenesis in the hippocampus, which has been proposed to contribute to antidepressant effects. Therefore, tremendous effort has been made to decipher how central 5-HT regulates adult hippocampal neurogenesis. In this paper, we review how changes in the central serotonergic system alter adult hippocampal neurogenesis. We focus on data obtained from three categories of genetically engineered mouse models: (1 mice with altered central 5-HT levels from embryonic stages, (2 mice with deletion of 5-HT receptors from embryonic stages, and (3 mice with altered central 5-HT system exclusively in adulthood. These recent findings provide unique insights to interpret the multifaceted roles of central 5-HT on adult hippocampal neurogenesis and its associated effects on depression.

Transmission Reinforcements in the Central American Regional Power System

Energy Technology Data Exchange (ETDEWEB)

Elizondo, Marcelo A.; Vallem, Mallikarjuna R.; Samaan, Nader A.; Makarov, Yuri V.; Vyakaranam, Bharat; Nguyen, Tony B.; Munoz, Christian; Herrera, Ricardo; Midence, Diego; Shpitsberg, Anna

2016-07-25

The Central American regional interconnected power system (SER) connects the countries members of the Central American regional electricity market (MER): Guatemala, El Salvador, Honduras, Nicaragua, Costa Rica, and Panama. The SER was a result of a long term regional effort, and was initially conceived to transfer 300 MW between countries. However, the current transfer limits between countries range from 70 MW to 300 MW. Regional entities, like CRIE (Regional Commission of Electrical Interconnection), EOR (Central American Regional System Operator), and CDMER (Board of Directors of the Central American Market) are working on coordinating the national transmission expansion plans with regional transmission planning efforts. This paper presents experience in Central America region to recommend transmission reinforcements to achieve 300 MW transfer capacity between any pair of member countries of the Central American regional electricity market (MER). This paper also provides a methodology for technical analysis and for coordination among the regional and national entities. This methodology is unique for transmission systems of these characteristics.

Chapter 1. Central nervous system

International Nuclear Information System (INIS)

Planiol, T.; Veyre, A.; Plagne, R.

1975-01-01

The present situation with regard to explorations of the central nervous system by radioactive compounds is reviewed. For the sake of clarity the brain and cerebrospinal fluid examinations are described separately, with emphasis nevertheless on their complementarity. The tracers used in each of these examinations are listed, together with the criteria governing their choice. The different techniques employed are described. Scintigraphy is presented apart from gamma-angio-encephalography since it is not possible with rectilinear scintigraphs to observe the circulatory phase. The results are interpreted by an analysis of normal and pathological aspects of the different stages of the central nervous system [fr

The democratic accountability of the European Central Bank

Directory of Open Access Journals (Sweden)

L. BINI-SMAGHI

1998-06-01

Full Text Available The European Central Bank (ECB is considered to be an institution with a high level of accountability compared with other central banks. However, the matter has yet to be investigated in practice. Accountability of the ECB will have to be checked by governing bodies both within and outside the ECB as well as the public. A survey is undertaken of the main reasons for central bank accountability, especially for the ECB.

Charmed and beauty baryon in hyper central model

International Nuclear Information System (INIS)

Patel, Bhavin; Vinodkumar, P.C.; Rai, Ajay Kumar

2006-01-01

For the present study the hyper central description of the three-body problem has been employed for the baryons constituting one or more charm and beauty quarks. The confinement potential is assumed in the hyper central co-ordinates as hyper central coulomb plus power potential. The charm and beauty baryons under this potential has been studied for different power indices starting from 0.5 to 2.0. The methods and results are briefly described

Neural correlates of central inhibition during physical fatigue.

Directory of Open Access Journals (Sweden)

Masaaki Tanaka

Full Text Available Central inhibition plays a pivotal role in determining physical performance during physical fatigue. Classical conditioning of central inhibition is believed to be associated with the pathophysiology of chronic fatigue. We tried to determine whether classical conditioning of central inhibition can really occur and to clarify the neural mechanisms of central inhibition related to classical conditioning during physical fatigue using magnetoencephalography (MEG. Eight right-handed volunteers participated in this study. We used metronome sounds as conditioned stimuli and maximum handgrip trials as unconditioned stimuli to cause central inhibition. Participants underwent MEG recording during imagery of maximum grips of the right hand guided by metronome sounds for 10 min. Thereafter, fatigue-inducing maximum handgrip trials were performed for 10 min; the metronome sounds were started 5 min after the beginning of the handgrip trials. The next day, neural activities during imagery of maximum grips of the right hand guided by metronome sounds were measured for 10 min. Levels of fatigue sensation and sympathetic nerve activity on the second day were significantly higher relative to those of the first day. Equivalent current dipoles (ECDs in the posterior cingulated cortex (PCC, with latencies of approximately 460 ms, were observed in all the participants on the second day, although ECDs were not identified in any of the participants on the first day. We demonstrated that classical conditioning of central inhibition can occur and that the PCC is involved in the neural substrates of central inhibition related to classical conditioning during physical fatigue.

MRI diagnosis of intraspinal dermoid ruptured into central spinal canal

International Nuclear Information System (INIS)

Zhang Yong; Cheng Jingliang; Wang Juan; Li Huali; Ren Cuiping; Zhang Yan; Gao Xuemei

2009-01-01

Objective: To evaluate the appearances of intraspinal dermoid ruptured into the central spinal canal, as well as the MRI diagnosis and differential diagnosis. Methods: Eleven cases of intraspinal dermoid ruptured into the central spinal canal were reviewed. Six cases underwent whole spine MRI scan, 2 cases with thoracic and lumbar spine MRI, as well as 3 cases only with lumbar spine MRI. Results: Free fat droplets within spinal cord central canal demonstrated high signal intensity on T 1 WI, slight declined signal intensity on T 2 WI, and extremely low signal on fat suppression sequence. Of the 11 cases, 2 cases broke into neighboring central spinal canal of the dermoid, 3 cases scattered within thoracic spinal cord central canal, 4 cases discontinuously distributed in the whole spinal cord central canal, 2 cases showed continuous distribution. Conclusion: Intraspinal dermoid ruptured in the central spinal canal had specific appearance on MRI, when a dermoid tumor is suspected, MRI of the entire spine were recommended to detect possible leakage of' fat within central spinal canal. (authors)

12 CFR 741.210 - Central liquidity facility.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Central liquidity facility. 741.210 Section 741... Unions That Also Apply to Federally Insured State-Chartered Credit Unions § 741.210 Central liquidity... Liquidity Facility, shall adhere to the requirements stated in part 725 of this chapter. ...

Centralized co-digestion and efficient nutrient recycling

Energy Technology Data Exchange (ETDEWEB)

Tafdrup, S [Danish Energy Agency, Copenhagen (Denmark)

1997-08-01

The centralized biogas plants co-digest animal manure and organic waste, producing biogas and liquid fertilizer as a result. 19 centralized biogas plants are in operation in Denmark. In 1996 they digested 200,000 tonnes organic industrial wastes with 800,000 tonnes manure. The average gate fee for waste reception is around DKK 50 per tonne. Thus, the centralized biogas plants provide the organic waste producers with an economically attractive as well as environmentally sound recycling option. The farmers play a key role. It is a precondition that the farmers benefit sufficiently from the operation of the centralized biogas plant. An average economic advantage for the farmers of approximately DKK 5 in all per m{sup 3} slurry has been calculated. Even though this is a relatively modest amount, it is enough to generate interest on the part of the farmers. A further tightening of the legislation is expected in a few years concerning utilization of nutrients in manure and land applied organic wastes. This, together with increasing focus on odour reduction, is expected to add to the farmers interests in centralized biogas plants. At present biogas contributes with 2 PJ per year to the energy supply in Denmark. According to the official energy action plan, the total biogas production from all kinds of biogas plants is to be doubled by the year 2000 and increased 10-fold by the year 2020. A major part of this increase is expected to come from new centralized biogas plants. The annual potential for biogas production from biomass resources available in Denmark is estimated to be approximately 30 PJ. Animal manure comprises about 80% of this potential. (au)

Control of gaseous emissions in central Costanera S.A. of Argentina; Control de emisiones gaseosas en central Costanera S. A. de Argentina

Energy Technology Data Exchange (ETDEWEB)

Brabenec, Edgardo [Unidad de Negocios Central Costanera, S. A., (Argentina)

1997-12-31

A description is presented of the equipment utilized at the Central Costanera, S.A. of Argentina, the requirements and the Environmental Management established for this Power Station, and the Standards and the resolutions and law instruments on Environmental issues. Also it is presented the Environmental Management plan of the Ente Nacional Regulador de Electricidad of Argentina as well as the controls and environmental corrective actions implemented at the Central Costanera, S.A. [Espanol] Se presenta una descripcion del equipo utilizado en la Central Costanera S.A. de Argentina, los requerimientos de gestion ambiental establecidos para esta central y las normas, resoluciones e instrumentos juridicos en materia ambiental. Se presenta ademas el plan de gestion ambiental del Ente Nacional Regulador de la Electricidad de Argentina asi como los controles y acciones correctivas ambientales implantadas en la Central Costanera S. A.

Control of gaseous emissions in central Costanera S.A. of Argentina; Control de emisiones gaseosas en central Costanera S. A. de Argentina

Energy Technology Data Exchange (ETDEWEB)

Brabenec, Edgardo [Unidad de Negocios Central Costanera, S. A., (Argentina)

1996-12-31

A description is presented of the equipment utilized at the Central Costanera, S.A. of Argentina, the requirements and the Environmental Management established for this Power Station, and the Standards and the resolutions and law instruments on Environmental issues. Also it is presented the Environmental Management plan of the Ente Nacional Regulador de Electricidad of Argentina as well as the controls and environmental corrective actions implemented at the Central Costanera, S.A. [Espanol] Se presenta una descripcion del equipo utilizado en la Central Costanera S.A. de Argentina, los requerimientos de gestion ambiental establecidos para esta central y las normas, resoluciones e instrumentos juridicos en materia ambiental. Se presenta ademas el plan de gestion ambiental del Ente Nacional Regulador de la Electricidad de Argentina asi como los controles y acciones correctivas ambientales implantadas en la Central Costanera S. A.

Midwifery education in Central-Eastern Europe.

Science.gov (United States)

Mivšek, Polona; Baškova, Martina; Wilhelmova, Radka

2016-02-01

Problems in midwifery in many Central-Eastern European countries are very similar; it is possible to speak about the evolving Central-Eastern model of midwifery care. The educational models of this region have a relatively strong theoretical part; however, there is an insufficient practical dimension. Theoretical part of midwifery education in the universities is relatively autonomous and is slowly changing the professional identity of graduates. Copyright © 2015 Elsevier Ltd. All rights reserved.

Geomorphic evidence of active faults growth in the Norcia seismic area (central Apennines, Italy)

Science.gov (United States)

Materazzi, Marco; Aringoli, Domenico; Farabollini, Piero; Giacopetti, Marco; Pambianchi, Gilberto; Tondi, Emanuele; Troiani, Francesco

2016-04-01

diversion, faulted deposits, deep-seated gravitational slope deformations and large landslides. Moreover the sub-basins represent the surface evidence of traits belonging to the Norcia seismogenic structure, which have repeatedly caused earthquakes in the past, thus determining similar geological, structural and morphostructural features within the wider Norcia area, without causing the whole structure to rupture. The size of these sub-basins and, thus, the size of the relevant seismogenic segments, allows to calculate a maximum magnitude for the three sub-basins and for the seismogenic area as a whole. References Aringoli D., Cavitolo P., Farabollini P., Galindo-Zaldivar J., Gentili B., Giano S.I., Lòpez-Garrido A.C.,. Materazzi M, Nibbi L., Pedrera A., Pambianchi G., Ruano P., Ruiz-Constàn A., Sanz de Galdeano C., Savelli D., Tondi E., Troiani F. 2014. Morphotectonic characterization of the quaternary intermontane basins in the Umbria-Marche Apennines (Italy). Rend. Fis. Acc. Lincei 25 (Suppl 2), S111-S128. DOI 10.1007/s12210-014-0330-0 CPTI, Working Group, 2004. Catalogo Parametrico Terremoti Italiani, ING, GNDT, SGA, SSN, 92 pp., Bologna. Tondi, E., Cello, G. 2003. Spatiotemporal Evolution of the Central Apennines Fault System (Italy). Journal of Geodynamics, 36, 113-128

Legislation on renewable energy sources in Central America

International Nuclear Information System (INIS)

Rebollo, Jose

2000-01-01

This paper presents the development of renewable energy in Central America and the cooperation given by the European Comission in the promotion of renewable energy sources. Also discuss the current situation in energy demand in Central America and possible solutions linked to legislation that promotes the inversion of the private sector. The legal framework in each country of Central America is presented and its impact in the increasing of generation of energy through tax reductions, trading and prices

Reliability of oscillometric central hemodynamic responses to an orthostatic challenge.

Science.gov (United States)

Stoner, Lee; Bonner, Chantel; Credeur, Daniel; Lambrick, Danielle; Faulkner, James; Wadsworth, Daniel; Williams, Michelle A

2015-08-01

Monitoring central hemodynamic responses to an orthostatic challenge may provide important insight into autonomic nervous system function. Oscillometric pulse wave analysis devices have recently emerged, presenting clinically viable options for investigating central hemodynamic properties. The purpose of the current study was to determine whether oscillometric pulse wave analysis can be used to reliably (between-day) assess central blood pressure and central pressure augmentation (augmentation index) responses to a 5 min orthostatic challenge (modified tilt-table). Twenty healthy adults (26.4 y (SD 5.2), 55% F, 24.7 kg/m(2) (SD 3.8)) were tested on 3 different mornings in the fasted state, separated by a maximum of 7 days. Central hemodynamic variables were assessed on the left arm using an oscillometric device. Repeated measures analysis of variance indicated a significant main effect of the modified tilt-table for all central hemodynamic variables (P response to the tilt, central diastolic pressure increased by 4.5 mmHg (CI: 2.6, 6.4), central systolic blood pressure increased by 2.3 (CI: 4.4, 0.16) mmHg, and augmentation index decreased by an absolute - 5.3%, (CI: -2.7, -7.9%). The intra-class correlation coefficient values for central diastolic pressure (0.83-0.86), central systolic blood pressure (0.80-0.87) and AIx (0.79-0.82) were above the 0.75 criterion in both the supine and tilted positions, indicating excellent between-day reliability. Central hemodynamic responses to an orthostatic challenge can be assessed with acceptable between-day reliability using oscillometric pulse wave analysis. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

FUNDUS AUTOFLUORESCENCE LIFETIMES AND CENTRAL SEROUS CHORIORETINOPATHY.

Science.gov (United States)

Dysli, Chantal; Berger, Lieselotte; Wolf, Sebastian; Zinkernagel, Martin S

2017-11-01

To quantify retinal fluorescence lifetimes in patients with central serous chorioretinopathy (CSC) and to identify disease specific lifetime characteristics over the course of disease. Forty-seven participants were included in this study. Patients with central serous chorioretinopathy were imaged with fundus photography, fundus autofluorescence, optical coherence tomography, and fluorescence lifetime imaging ophthalmoscopy (FLIO) and compared with age-matched controls. Retinal autofluorescence was excited using a 473-nm blue laser light and emitted fluorescence light was detected in 2 distinct wavelengths channels (498-560 nm and 560-720 nm). Clinical features, mean retinal autofluorescence lifetimes, autofluorescence intensity, and corresponding optical coherence tomography (OCT) images were further analyzed. Thirty-five central serous chorioretinopathy patients with a mean visual acuity of 78 ETDRS letters (range, 50-90; mean Snellen equivalent: 20/32) and 12 age-matched controls were included. In the acute stage of central serous chorioretinopathy, retinal fluorescence lifetimes were shortened by 15% and 17% in the respective wavelength channels. Multiple linear regression analysis showed that fluorescence lifetimes were significantly influenced by the disease duration (P autofluorescence lifetimes, particularly in eyes with retinal pigment epithelial atrophy, were associated with poor visual acuity. This study establishes that autofluorescence lifetime changes occurring in central serous chorioretinopathy exhibit explicit patterns which can be used to estimate perturbations of the outer retinal layers with a high degree of statistical significance.

How safe are Indian laboratories?

Digital Repository Service at National Institute of Oceanography (India)

Iyer, S.D.

of the laboratories could be time bombs tic k- ing away slowly but surely. What needs to be done to make the work enviro n- ment safer and user - friendly? The ens u- ing are a few suggestions. Probably these are adopted in some laboratories but they may...

Distributed generation and centralized power system in Thailand

DEFF Research Database (Denmark)

Sukkumnoed, Decharut

2004-01-01

The paper examines and discusses conflicts between the development of distributed power and centralized power system.......The paper examines and discusses conflicts between the development of distributed power and centralized power system....

Centralization and Decentralization in American Education Policy

Science.gov (United States)

DeBoer, Jennifer

2012-01-01

This article examines the trend toward centralization in American education policy over the last century through a variety of lenses. The overall picture that emerges is one of a continuous tug-of-war, with national and local policymakers stumbling together toward incrementally more standardized and centralized policies. There is a center of power…

Percutaneous transfemoral repositioning of malpositioned central venous catheters.

Science.gov (United States)

Hartnell, G G; Roizental, M

1995-04-01

Central venous catheters inserted by blind surgical placement may not advance into a satisfactory position and may require repositioning. Malpositioning via surgical insertion is common in patients in whom central venous catheters have previously been placed, as these patients are more likely to have central venous thrombosis and distortion of central venous anatomy. This is less of a problem when catheter placement is guided by imaging; however, even when insertion is satisfactory, central venous catheters may become displaced spontaneously after insertion (Fig. 1). Repositioning can be effected by direct manipulation using guidewires or tip-deflecting wires [1, 2], by manipulation via a transfemoral venous approach [3-5], and by injection of contrast material or saline [6]. Limitations of the direct approach include (1) the number and type of maneuvers that can be performed to effect repositioning when anatomy is distorted, (2) difficulty in accessing the catheter, and (3) the risk of introducing infection. Moreover, these patients are often immunosuppressed, and there is a risk of introducing infection by exposing and directly manipulating the venous catheter. Vigorous injection of contrast material or saline may be unsuccessful for the same reasons: It seldom exerts sufficient force to reposition large-caliber central venous catheters and may cause vessel damage or rupture if injection is made into a small or thrombosed vessel. We illustrate several alternative methods for catheter repositioning via a transfemoral venous approach.

Energy sector developments in Central America and the Caribbean

International Nuclear Information System (INIS)

Perez, J.

1997-01-01

Energy sector developments in Central America and the Caribbean were discussed. Central America is composed of six small countries whose total population is 32 million. The Caribbean population is 20.5 million. Central America is generally poor in hydrocarbon reserves but the geological prospects in several of the countries are encouraging. The oil and petroleum products supply and demand picture, the main characteristics of the hydrocarbon market, structure of the oil industry, hydrocarbon market reforms, pricing issues and recent trend towards reforms in the electric power industry in Central America were discussed. An overview of the Inter-American Development Bank's (IDB) effort to provide technical assistance and loans to strengthen the energy sector development in Central America and the Caribbean was also given. 17 refs., 2 tabs., 23 figs

Fractal systems of central places based on intermittency of space-filling

International Nuclear Information System (INIS)

Chen Yanguang

2011-01-01

Highlights: → The idea of intermittency is introduced into central place model. → The revised central place model suggests incomplete space filling. → New central place fractals are presented for urban analysis. → The average nearest distance is proposed to estimate the fractal dimension. → The concept of distance-based space is replaced by that of dimension-based space. - Abstract: The central place models are fundamentally important in theoretical geography and city planning theory. The texture and structure of central place networks have been demonstrated to be self-similar in both theoretical and empirical studies. However, the underlying rationale of central place fractals in the real world has not yet been revealed so far. This paper is devoted to illustrating the mechanisms by which the fractal patterns can be generated from central place systems. The structural dimension of the traditional central place models is d = 2 indicating no intermittency in the spatial distribution of human settlements. This dimension value is inconsistent with empirical observations. Substituting the complete space filling with the incomplete space filling, we can obtain central place models with fractional dimension D < d = 2 indicative of spatial intermittency. Thus the conventional central place models are converted into fractal central place models. If we further integrate the chance factors into the improved central place fractals, the theory will be able to explain the real patterns of urban places very well. As empirical analyses, the US cities and towns are employed to verify the fractal-based models of central places.

MR findings of central nerocytoma

International Nuclear Information System (INIS)

Lee, Chang Hoon; Kim, Dong Ik; Lee, Byung Hee; Kim, Myung Soon

1997-01-01

Central neurocytoma is a reae neuronal differentiated intraventricular tomor of young adults. The purpose of this study was to evaluate the characteristic MR appearance of central neurocytoma. We retrospectively reviewed MR images of 12 patients with central neurocytoma, confirmed by ultrastructural and immunohistochemical study. We analyzed patient age, and on all sequences, tumor location, extension into the third ventricle, involvement of brain parenchyma, cyst, hemorrhage, vascular signal void and signal intensity ; and egree of Gd-enhancement was examined on MR images, pattern of calcification on CT, and neovascularity, tumor staining on angiography. Age distribution was wide ranging from 26 to 64 years ; the most frequent age group was the fourth decade (five patients). All tumors except one (in the third ventricle) were located in the lateral ventricle and most were seen in the region of the foramen of Monro (10 cases). Tumors showed extension into the third ventricle and involvement of parenchyma in three cases. The internal architecture of the tumor was heterogenous and consisted of cysts (83%), hemorrhage (25%) and vascular signal void (25%). The solid portion of the tumor showed variable signal intensity on T1-weighted images and iso or high signal intensity on T2- and proton density-weighted images. On MR imaging, mild to moderate heterogenous Gd-enhancement was seen in ten cases (83%), and on CT, a spotted, amorphous, nodular pattern of calcifications was seen in seven cases (63%). On angiography, neovasevlarity and tumor staining was seen in three cases (100%). The typical location of the lateral and third ventricles and MR imaging characteristics including variable signal intensity and heterogenous internal architecture are helpful in the diagnosis of central neurocytoma in young adults

Prevalence and lifestyle determinants of central obesity in children.

Science.gov (United States)

Grigorakis, Dimitris A; Georgoulis, Michael; Psarra, Glykeria; Tambalis, Konstantinos D; Panagiotakos, Demosthenes B; Sidossis, Labros S

2016-08-01

Central obesity is a strong risk factor for metabolic disorders and cardiometabolic diseases in children and adolescents. The aim of the present study was to evaluate the prevalence of central obesity and to determine its cross-sectional association with lifestyle habits in a sample of school-aged children in Greece. The study sample consisted of 124,113 children (9.9 ± 1.1 years old, 51 % boys) attending the third and fifth grade of primary school. Anthropometric measurements were performed by trained physical education teachers, and central obesity was defined as waist-to-height ratio ≥0.5. Children's lifestyle habits were assessed through 7-day recall questionnaires. Of the participating children, 33.4 % were classified as centrally obese. Central obesity was significantly more prevalent in boys than in girls (36.0 vs. 30.7 %, P obese children, as well as in a significant percentage of overweight (69.5 %) and normal-weight ones (12.0 %). Children with central obesity, compared to their non-centrally obese counterparts, reported poorer dietary habits and were less physically active. According to multiple logistic regression analysis, frequent breakfast (OR 0.72, 95 % CI 0.69-0.75) and snack consumption (OR 0.70, 95 % CI 0.67-0.74), as well as frequent participation in sedentary activities (OR 1.10, 95 % CI 1.07-1.14), were the strongest lifestyle determinants of central obesity. Strategies for the prevention of central obesity and associated comorbidities are urgently needed, for both obese and non-obese children. Our results suggest the need for a shift towards a healthier environment for our children, with emphasis on specific lifestyle habits, such as regular meal consumption and low sedentariness.

The central noradrenergic system

African Journals Online (AJOL)

2006-07-27

Jul 27, 2006 ... recognition of a direct influence of the central noradrenergic system on peripheral ... influences on cerebral function and behavior it is impossible to imagine ... stimuli and to speed-up information processing.4. The influence of ...

Central nervous system complications in non-Hodgkin-lymphomas and radiotherapy

International Nuclear Information System (INIS)

Liffers, R.

1981-01-01

261 case historys of malignant non-Hodgkin-lymphomas were analysed in the years from 1969 until 1978 in the 'Radiologische Universitaetsklinik Kiel'/West-Germany. 18 Patients got a central nervous complication of Non Hodgkin-Lymphoma earlier or later, a percentage of about 7. There were 7 cases of lymphoblastic lymphoma (LB), a percentage of 10 for this entity. In the group of immunoblastic lymphoma (IB) 6 cases of central nervous infiltration were detected, that is a ratio of 7.7 percent. 4 case histories M. Brill-Symmers (CC/CB) were complicated by central nervous dissemination, a percentage of 5.3. Patients with lymphoblastic lymphoma have the highest risk of central nervous complication. The beginning of central nervous dissemination in the single case histories is very different between the histological groups. Patients with lymphoblastic lymphoma suffered from central nervous complication in an early phase of history, in cases of M. Brill-Symmers central nervous infiltration can occur also in a late phase. The results may determine the discussion about stratifying of radiotherapy. Early radiotherapy including central nervous system may be discussed and investigated in special histological entities of malignant non-Hodgkin-lymphoma. (orig.) [de

Brain MR imaging finding in patients with central vertigo

Energy Technology Data Exchange (ETDEWEB)

Jeong, Chun Keun; Kim, Sang Joon; Kim, You Me; Cha, Min Jung; Lee, Young Seok; Kim, Jae Il; Lee, Geun Ho; Rhee, Chung Koo; Park, Hyun Min [Dankook Univ. College of Medicine, Chonan (Korea, Republic of)

1998-11-01

To investigate brain lesions and their locations in patients with central vertigo, as seen on MR imaging. We retrospectively reviewed MR images of 85 patients with central type vertigo diagnosed on the basis of clinical symptoms and vestibular function test(VFT), and analyzed lesions fand their locations. Those located along the known central vestibular pathway were included in our study. In 29 of 85 patients(34%), lesions considered to be associated with central vertigo were detected on MR imaging. These included infarction(18 patients), hemorrhage(5), tumor(2), cavernous angioma(1), cerebellopontine angle cyst(1), tuberous sclerosis(1) and olivopontocerebellar atrophy (1);they were located in the parietal lobe(6 patients), the lateral medulla(5), the pons(5), the middle cerebellar peduncle(4), the corona radiata(3), and the cerebellar vermis(3). Thirty-eight cases showed high signal intensity lesions in deep cerebral matter, the basal ganglia, and pons but these were considered to be unrelated to central vertigo. MR imaging could be a useful tool for the evaluation of patients with central vertigo.=20.

Brain MR imaging finding in patients with central vertigo

International Nuclear Information System (INIS)

Jeong, Chun Keun; Kim, Sang Joon; Kim, You Me; Cha, Min Jung; Lee, Young Seok; Kim, Jae Il; Lee, Geun Ho; Rhee, Chung Koo; Park, Hyun Min

1998-01-01

To investigate brain lesions and their locations in patients with central vertigo, as seen on MR imaging. We retrospectively reviewed MR images of 85 patients with central type vertigo diagnosed on the basis of clinical symptoms and vestibular function test(VFT), and analyzed lesions fand their locations. Those located along the known central vestibular pathway were included in our study. In 29 of 85 patients(34%), lesions considered to be associated with central vertigo were detected on MR imaging. These included infarction(18 patients), hemorrhage(5), tumor(2), cavernous angioma(1), cerebellopontine angle cyst(1), tuberous sclerosis(1) and olivopontocerebellar atrophy (1);they were located in the parietal lobe(6 patients), the lateral medulla(5), the pons(5), the middle cerebellar peduncle(4), the corona radiata(3), and the cerebellar vermis(3). Thirty-eight cases showed high signal intensity lesions in deep cerebral matter, the basal ganglia, and pons but these were considered to be unrelated to central vertigo. MR imaging could be a useful tool for the evaluation of patients with central vertigo.=20

The interdealer market and the central bank intervention

OpenAIRE

Paula Albuquerque

2005-01-01

This paper studies the consequences of having either an interventionist or a non-interventionist central bank in the foreign exchange market, in a market microstructure framework. Although a simple one-period model is used, it allows the characterization of the effect of the central bank intervention on the behaviour of dealers. The model also identifies the conditions for the dealer that acts as the counterpart of the central bank to be better or worse than the other dealers. The price is ex...

Archives: East and Central African Journal of Surgery

African Journals Online (AJOL)

Items 1 - 40 of 40 ... Archives: East and Central African Journal of Surgery. Journal Home > Archives: East and Central African Journal of Surgery. Log in or Register to get access to full text downloads.

central t

Directory of Open Access Journals (Sweden)

Manuel R. Piña Monarrez

2007-01-01

Full Text Available Dado que la Regresión Ridge (RR, es una estimación sesgada que parte de la solución de la regresión de Mínimos Cuadrados (MC, es vital establecer las condiciones para las que la distribución central t de Student que se utiliza en la prueba de hipótesis en MC, sea también aplicable a la regresión RR. La prueba de este importante resultado se presenta en este artículo.

Reliability of oscillometric central hemodynamic responses to an orthostatic challenge

OpenAIRE

Stoner, Lee; Bonner, Chantel; Credeur, Daniel; Lambrick, Danielle; Faulkner, James; Wadsworth, Daniel; Williams, Michelle A.

2015-01-01

BackgroundMonitoring central hemodynamic responses to an orthostatic challenge may provide important insight into autonomic nervous system function. Oscillometric pulse wave analysis devices have recently emerged, presenting clinically viable options for investigating central hemodynamic properties. The purpose of the current study was to determine whether oscillometric pulse wave analysis can be used to reliably (between-day) assess central blood pressure and central pressure augmentation (a...

An overview of CMS central hadron calorimeter

CERN Document Server

Katta, S

2002-01-01

The central hadron calorimeter for CMS detector is a sampling calorimeter with active medium as scintillator plates interleaved with brass absorber plates. It covers the central pseudorapidity region (¿ eta ¿<3.0). The design and construction aspects are reported. The status of construction and assembly of various subdetectors of HCAL are presented. (5 refs).

Switchings, extensions, and reductions in central digraphs

DEFF Research Database (Denmark)

Kündgen, André; Leander, Gregor; Thomassen, Carsten

2011-01-01

A directed graph is called central if its adjacency matrix A satisfies the equation A2=J, where J is the matrix with a 1 in each entry. It has been conjectured that every central directed graph can be obtained from a standard example by a sequence of simple operations called switchings, and also ...

Visualizing the Central Limit Theorem through Simulation

Science.gov (United States)

Ruggieri, Eric

2016-01-01

The Central Limit Theorem is one of the most important concepts taught in an introductory statistics course, however, it may be the least understood by students. Sure, students can plug numbers into a formula and solve problems, but conceptually, do they really understand what the Central Limit Theorem is saying? This paper describes a simulation…

Central nervous system resuscitation

DEFF Research Database (Denmark)

McIntosh, T K; Garde, E; Saatman, K E

1997-01-01

Traumatic injury to the central nervous system induces delayed neuronal death, which may be mediated by acute and chronic neurochemical changes. Experimental identification of these injury mechanisms and elucidation of the neurochemical cascade following trauma may provide enhanced opportunities...

alpha-MSH in systemic inflammation. Central and peripheral actions.

Science.gov (United States)

Catania, A; Delgado, R; Airaghi, L; Cutuli, M; Garofalo, L; Carlin, A; Demitri, M T; Lipton, J M

1999-10-20

Until recently, inflammation was believed to arise from events taking place exclusively in the periphery. However, it is now clear that central neurogenic influences can either enhance or modulate peripheral inflammation. Therefore, it should be possible to improve treatment of inflammation by use of antiinflammatory agents that reduce peripheral host responses and inhibit proinflammatory signals in the central nervous system (CNS). One such strategy could be based on alpha-melanocyte stimulating hormone (alpha-MSH). Increases in circulating TNF-alpha and nitric oxide (NO), induced by intraperitoneal administration of endotoxin in mice, were modulated by central injection of a small concentration of alpha-MSH. Inducible nitric oxide synthase (iNOS) activity and iNOS mRNA in lungs and liver were likewise modulated by central alpha-MSH. Increase in lung myeloperoxidase (MPO) activity was significantly less in lungs of mice treated with central alpha-MSH. Proinflammatory agents induced by endotoxin were significantly greater after blockade of central alpha-MSH. The results suggest that antiinflammatory influences of neural origin that are triggered by alpha-MSH could be used to treat systemic inflammation. In addition to its central influences, alpha-MSH has inhibitory effects on peripheral host cells, in which it reduces release of proinflammatory mediators. alpha-MSH reduces chemotaxis of human neutrophils and production of TNF-alpha, neopterin, and NO by monocytes. In research on septic patients, alpha-MSH inhibited release of TNF-alpha, interleukin-1 beta (IL-1 beta), and interleukin-8 (IL-8) in whole blood samples in vitro. Combined central and peripheral influences can be beneficial in treatment of sepsis.

Monitoring System with Two Central Facilities Protocol

Directory of Open Access Journals (Sweden)

Caesar Firdaus

2017-03-01

Full Text Available The security of data and information on government’s information system required proper way of defending against threat. Security aspect can be achieved by using cryptography algorithm, applying information hiding concept, and implementing security protocol. In this research, two central facilities protocol was implemented on Research and Development Center of Mineral and Coal Technology’s Cooperation Contract Monitoring System by utilizing AES and whitespace manipulation algorithm. Adjustment on the protocol by creating several rule of validation ID’s generation and checking processes could fulfill two of four cryptography objectives, consist of authentication and non-repudiation. The solid collaboration between central legitimization agency (CLA, central tabulating facility (CTF, and client is the main idea in two central facilities protocol. The utilization of AES algorithm could defend the data on transmission from man in the middle attack scenario. On the other hand, whitespace manipulation algorithm provided data integrity aspect of the document that is uploaded to the system itself. Both of the algorithm fulfill confidentiality, data integrity, and authentication.

Interactions et formalisations intersubjectives

OpenAIRE

Bouvet, Rose-Marie

2008-01-01

L'ingénierie, modélisation nécessaire et leurranteDéfinir l'ingénierieL'ingénierie de formation est née d'une volonté de rationaliser des coûts et des pratiques de formation. A cette logique d'efficacité impulsée par les commanditaires et financeurs, (du secteur privé comme du secteur public), notamment depuis la mise en place de la formation professionnelle continue et des politiques d'insertion et réinsertion professionnelle, s'est développée la mise en cause d'un modèle d'enseignement axé ...

Central extensions of some Abelian finite gauge groups

International Nuclear Information System (INIS)

Combe, Ph.; Rodriguez, R.; Sirugue, M.; Sirugue-Collin, M.

1981-01-01

The authors describe central extensions of Abelian finite gauge groups on lattices which are permutation invariant. Moreover some remarks are made on the gauge models on lattice associated with these non-commutative central extensions. (Auth.)

Inventory Centralization Decision Framework for Spare Parts

DEFF Research Database (Denmark)

Gregersen, Nicklas; Herbert-Hansen, Zaza Nadja Lee

2018-01-01

Within the current literature, there is a lack of a holistic and multidisciplinary approach to managing spare parts and their inventory configuration. This paper addresses this research gap by examining the key contextual factors which influence the degree of inventory centralization and proposes...... a novel holistic theoretical framework, the Inventory Centralization Decision Framework (ICDF), useful for practitioners. Through an extensive review of inventory management literature, six contextual factors influencing the degree of inventory centralization have been identified. Using the ICDF...... practitioners can assess the most advantageous inventory configuration of spare parts. The framework is tested on a large global company which, as a result, today actively uses the ICDF; thus showing its practical applicability....

Centralized vs. decentralized child mental health services.

Science.gov (United States)

Adams, M S

1977-09-01

One of the basic tenets of the Community Mental Health Center movement is that services should be provided in the consumers' community. Various centers across the country have attempted to do this in either a centralized or decentralized fashion. Historically, most health services have been provided centrally, a good example being the traditional general hospital with its centralized medical services. Over the years, some of these services have become decentralized to take the form of local health centers, health maintenance organizations, community clinics, etc, and now various large mental health centers are also being broken down into smaller community units. An example of each type of mental health facility is delineated here.

Nuclear Energy in Central Europe 98, Proceedings

International Nuclear Information System (INIS)

Ravnik, M.; Jencic, I.; Zagar, T.

1998-01-01

Regional Meeting for Nuclear Energy in Central Europe is an annual meeting of the Nuclear Society of Slovenia. The proceedings contain 63 articles from Slovenia, sorounding countries and countries of the Central and Eastern European Region. Topics are: Research Reactors, Nuclear Methods, Reactor Physics, Thermal Hydraulics, Structural Analysis, Probabilistic Safety Assessment, Severe Accidents, NPP Operation and Nuclear Waste disposal

Central control system for the EAST tokamak

International Nuclear Information System (INIS)

Sun Xiaoyang; Ji Zhenshan; Wu Yicun; Luo Jiarong

2008-01-01

The architecture, the main function and the design scheme of the central control system and the collaboration system of EAST tokamak are described. The main functions of the central control system are to supply a union control interface for all the control, diagnoses, and data acquisition (DAQ) subsystem and it is also designed to synchronize all those subsystem. (authors)

Centralized, Decentralized, and Hybrid Purchasing Organizations

DEFF Research Database (Denmark)

Bals, Lydia; Turkulainen, Virpi

This paper addresses one of the focal issues in purchasing and supply management – global sourcing – from an organizational design perspective. In particular, we elaborate the traditional classification of global sourcing organization designs into centralized, decentralized, and hybrid models. We...... organization we can identify organization designs beyond the classical centralization-decentralization continuum. We also provide explanations for the observed organization design at GCC. The study contributes to research on purchasing and supply management as well as research on organization design....

Central nervous system complications after liver transplantation.

Science.gov (United States)

Kim, Jeong-Min; Jung, Keun-Hwa; Lee, Soon-Tae; Chu, Kon; Roh, Jae-Kyu

2015-08-01

We investigated the diversity of central nervous system complications after liver transplantation in terms of clinical manifestations and temporal course. Liver transplantation is a lifesaving option for end stage liver disease patients but post-transplantation neurologic complications can hamper recovery. Between 1 January 2001 and 31 December 2010, patients who had undergone liver transplantation at a single tertiary university hospital were included. We reviewed their medical records and brain imaging data and classified central nervous system complications into four categories including vascular, metabolic, infectious and neoplastic. The onset of central nervous system complications was grouped into five post-transplantation intervals including acute (within 1 month), early subacute (1-3 months), late subacute (3-12 months), chronic (1-3 years), and long-term (after 3 years). During follow-up, 65 of 791 patients (8.2%) experienced central nervous system complications, with 30 occurring within 1 month after transplantation. Vascular etiology was the most common (27 patients; 41.5%), followed by metabolic (23; 35.4%), infectious (nine patients; 13.8%), and neoplastic (six patients). Metabolic encephalopathy with altered consciousness was the most common etiology during the acute period, followed by vascular disorders. An initial focal neurologic deficit was detected in vascular and neoplastic complications, whereas metabolic and infectious etiologies presented with non-focal symptoms. Our study shows that the etiology of central nervous system complications after liver transplantation changes over time, and initial symptoms can help to predict etiology. Copyright © 2015 Elsevier Ltd. All rights reserved.

Central European projects could alter oil movement patterns

International Nuclear Information System (INIS)

Deffarges, E.H.; Howard, D.J.; Treat, J.E.

1991-01-01

This paper reports that several oil transportation projects are set to transform the flows of oil in Central Europe, with potentially important implications for crude oil and product prices in the region. These projects are spurred by the desires of the newly opened economies of Central Europe to diversify their sources of oil supplies away from the U.S.S.R. and by expectations of economic growth in this region. Today, Central European countries (Poland, Czechoslovakia, Hungary, Yugoslavia, Romania, and Bulgaria) rely heavily on Soviet crude supplies. Of the 1.7 million b/d of crude oil consumed by these six countries, about 55% is imported from the U.S.S.R. This is down significantly from the more than 75% import dependence in the mid-1980s. This dependency on U.S.S.R. crude - for countries that either have a history of indigenous production (Romania) or access to Middle East or North African supplies (Yugoslavia) - testifies to more than 40 years of centrally planned economics in which Moscow provided the energy and raw materials and Central European countries delivered finished goods. Since the end of World War II, the pipeline flow of crude oil and products from Western to Central Europe has been almost nonexistent. In fact, the Western European crude and product pipeline network itself is a rather poorly integrated system, with only limited interconnections between northern and southern networks and no real competition across the major flow routes

Does Al Qaeda Central Still Matter?

Directory of Open Access Journals (Sweden)

Kangil Lee

2015-01-01

Full Text Available El artículo discute si Al Qaeda central es todavía relevante o no. Tras estudiar la actividades de Al Qaeda central cuyo objetivo es provocar la violencia en Afganistán y Pakistán, así como los planes continuos de ataques directos contra los Estados Unidos, el artículo muestra que la capacidad operativa de Al Qaeda es más sólida y fuerte que la que Estados Unidos y otros investigadores y eruditos han anticipado. Además, el apoyo virulento y la contribución Al Qaeda en la Península Arábiga a la red de Al Qaeda muestra que la longevidad de Al Qaeda depende de la relación con sus afiliados. El artículo concluye que, en estas condiciones, Al Qaeda central todavía ocupa un lugar en las discusiones de seguridad global.

Central neurotoxicity of immunomodulatory drugs in multiple myeloma

Directory of Open Access Journals (Sweden)

Urmeel H. Patel

2015-03-01

Full Text Available Immunomodulatory drugs (IMiDs currently used in the treatment of multiple myeloma, are thalidomide, lenalidomide and pomalidomide. One of the most common side effects of thalidomide is neurotoxicity, predominantly in the form of peripheral neuropathy. We report 6 cases of significant central neurotoxicity associated with IMiD therapy. Treatment with thalidomide (1 patient, lenalidomide (4 patients, and pomalidomide (1 patient was associated with various clinical manifestations of central neurotoxicity, including reversible coma, amnesia, expressive aphasia, and dysarthria. Central neurotoxicity should be recognized as an important side effect of IMiD therapy.

Central neurotoxicity of immunomodulatory drugs in multiple myeloma.

Science.gov (United States)

Patel, Urmeel H; Mir, Muhammad A; Sivik, Jeffrey K; Raheja, Divisha; Pandey, Manoj K; Talamo, Giampaolo

2015-02-24

Immunomodulatory drugs (IMiDs) currently used in the treatment of multiple myeloma, are thalidomide, lenalidomide and pomalidomide. One of the most common side effects of thalidomide is neurotoxicity, predominantly in the form of peripheral neuropathy. We report 6 cases of significant central neurotoxicity associated with IMiD therapy. Treatment with thalidomide (1 patient), lenalidomide (4 patients), and pomalidomide (1 patient) was associated with various clinical manifestations of central neurotoxicity, including reversible coma, amnesia, expressive aphasia, and dysarthria. Central neurotoxicity should be recognized as an important side effect of IMiD therapy.

Seismotectonic model of Central Europe

International Nuclear Information System (INIS)

Prochazkova, D.; Roth, Z.

1994-01-01

Earthquakes belong to natural disasters which are associated with tectonic processes in the interior of the Earth. They are extremely devastating in populated areas; they cause human losses and damage personal estates and the environment. To mitigate the potential effects of earthquakes it is necessary that relief and mitigation structures operate following an earthquake, but it is also essential to stimulate and enhance preparedness and prevention. Prevention includes the development of scenarios of potential earthquakes, hazard mapping, formulation of regulations, etc. Preparedness includes the installation and operation of warning systems, establishing communication networks to operate before, during, and after earthquakes. As nuclear technology belongs to high-risk technologies with regard to human health and the environment and its hazard substantially increases in consequence of earthquakes, in the siting of a nuclear plant engineering solutions are generally available to mitigate the potential vibratory effects through design. For the choice of a suitable engineering solution, reliable data must be processed by reliable techniques. The IAEA safety guide of the safety series No. 50-SG-S1(Rev. 1) specifies the demands on data and on their processing and also on the regional seismotectonic model. With a view of this the regional seismotectonic model of Central Europe was created. The paper presents regional geological characteristics of Central Europe and a chronological model of neotectonic movements in Central Europe with specification of neotectonic regional units and their present movements. Moreover, it contains earthquake characteristics for Central Europe and the specification of seismogenic movements. It was found that the genesis of local regions with occurrence of the strongest earthquakes is connected with several movement trends in the last 5 Ma. Six more or less tectonically separate regional units were revealed. The earthquake epicenters often

Understanding the centrality deficit: insight from foreign language learners.

Science.gov (United States)

Miller, Amanda C; Keenan, Janice M

2011-07-01

This study replicated and extended a phenomenon in the text memory literature referred to as the centrality deficit Miller & Keenan (Annals of Dyslexia 59:99-113, 2009). It examined how reading in a foreign language (L2) affects one's text representation and ability to recall the most important information. Readers recalled a greater proportion of central than of peripheral ideas, regardless of whether reading in their native language (L1) or a foreign language (L2). Nonetheless, the greatest deficit in participants' L2 recalls, as compared with L1 recalls, was on the central, rather than the peripheral, information. This centrality deficit appears to stem from resources being diverted from comprehension when readers have to devote more cognitive resources to lower level processes (e.g., L2 word identification and syntactic processing), because the deficit was most evident among readers who had lower L2 proficiency. Prior knowledge (PK) of the passage topic helped compensate for the centrality deficit. Readers with less L2 proficiency who did not have PK of the topic displayed a centrality deficit, relative to their L1 recall, but this deficit dissipated when they did possess PK.

Central dot sign in entities other than Caroli disease

International Nuclear Information System (INIS)

Ahmadi, T.; Itai, Yuji; Minami, Manabu.

1997-01-01

The purpose of this study was to describe central dot sign (tiny dots with strong contrast enhancement of the portal vein within dilated hepatic bile ducts on computed tomography) in entities other than Caroli disease, especially in peribiliary cysts with or without autosomal-dominant polycystic kidney disease. Computed tomography in 74 cases of peribiliary cysts and 134 cases of other liver diseases and states possibly showing central dot sign were retrospectively reviewed to examine the central dot sign. In three cases of peribiliary cysts, some part of the liver showed strongly enhanced portal radicles surrounded completely or partially by low-attenuation, enlarged peribiliary cysts, presenting ''central dot sign'' on contrast-enhanced computed tomography. We suggest that in addition to Caroli disease, some other entities and diseases of the liver may demonstrate central dot sign and this sign should not be considered a specific finding of Caroli disease. (author)

Central dot sign in entities other than Caroli disease

Energy Technology Data Exchange (ETDEWEB)

Ahmadi, T.; Itai, Yuji [Tsukuba Univ., Ibaraki (Japan). Inst. of Clinical Medicine; Minami, Manabu

1997-11-01

The purpose of this study was to describe central dot sign (tiny dots with strong contrast enhancement of the portal vein within dilated hepatic bile ducts on computed tomography) in entities other than Caroli disease, especially in peribiliary cysts with or without autosomal-dominant polycystic kidney disease. Computed tomography in 74 cases of peribiliary cysts and 134 cases of other liver diseases and states possibly showing central dot sign were retrospectively reviewed to examine the central dot sign. In three cases of peribiliary cysts, some part of the liver showed strongly enhanced portal radicles surrounded completely or partially by low-attenuation, enlarged peribiliary cysts, presenting ``central dot sign`` on contrast-enhanced computed tomography. We suggest that in addition to Caroli disease, some other entities and diseases of the liver may demonstrate central dot sign and this sign should not be considered a specific finding of Caroli disease. (author)

Budget deficits, monetization, and central-bank independence in developing countries

NARCIS (Netherlands)

Sikken, BJ; de Haan, J

Using various indicators for central bank independence we examine the relationship between central bank independence and government budget deficits. Using a two-stage procedure we also analyze whether central bank independence affects the monetization of deficits. First, the monetization relation in

The organisational structure of protein networks: revisiting the centrality-lethality hypothesis.

Science.gov (United States)

Raman, Karthik; Damaraju, Nandita; Joshi, Govind Krishna

2014-03-01

Protein networks, describing physical interactions as well as functional associations between proteins, have been unravelled for many organisms in the recent past. Databases such as the STRING provide excellent resources for the analysis of such networks. In this contribution, we revisit the organisation of protein networks, particularly the centrality-lethality hypothesis, which hypothesises that nodes with higher centrality in a network are more likely to produce lethal phenotypes on removal, compared to nodes with lower centrality. We consider the protein networks of a diverse set of 20 organisms, with essentiality information available in the Database of Essential Genes and assess the relationship between centrality measures and lethality. For each of these organisms, we obtained networks of high-confidence interactions from the STRING database, and computed network parameters such as degree, betweenness centrality, closeness centrality and pairwise disconnectivity indices. We observe that the networks considered here are predominantly disassortative. Further, we observe that essential nodes in a network have a significantly higher average degree and betweenness centrality, compared to the network average. Most previous studies have evaluated the centrality-lethality hypothesis for Saccharomyces cerevisiae and Escherichia coli; we here observe that the centrality-lethality hypothesis hold goods for a large number of organisms, with certain limitations. Betweenness centrality may also be a useful measure to identify essential nodes, but measures like closeness centrality and pairwise disconnectivity are not significantly higher for essential nodes.

Connecting Students, Creating Futures at Central Campus

Science.gov (United States)

Rosin, Julie; Erbes, Elizabeth; Britt, James; Good, Bill

2012-01-01

Des Moines is an urban community located in the heart of Iowa. Des Moines Public Schools serves 32,000 students in a system with 62 buildings, including Central Campus--a Regional Academy. Central Campus is housed in four buildings, including the main campus at 1800 Grand located on the western edge of downtown Des Moines. As a regional academy,…

Nonlinear Squeeze Film Dampers without Centralized Springs

Directory of Open Access Journals (Sweden)

Zhu Changsheng

2000-01-01

Full Text Available In this paper, the bifurcation behavior of a flexible rotor supported on nonlinear squeeze film dampers without centralized springs is analyzed numerically by means of rotor trajectories, Poincar maps, bifurcation diagrams and power spectra, based on the short bearing and cavitated film assumptions. It is shown that there also exist two different operations (i.e., socalled bistable operations in some speed regions in the rotor system supported on the nonlinear squeeze film dampers without centralized springs. In the bistable operation speed regions, the rotor system exhibits synchronous, sub-synchronous, sub-super-synchronous and almost-periodic as well as nonperiodic motions. The periodic bifurcation behaviors of the rotor system supported on nonlinear squeeze film dampers without centralized springs are very complex and require further investigations.

Centralized versus distributed propulsion

Science.gov (United States)

Clark, J. P.

1982-01-01

The functions and requirements of auxiliary propulsion systems are reviewed. None of the three major tasks (attitude control, stationkeeping, and shape control) can be performed by a collection of thrusters at a single central location. If a centralized system is defined as a collection of separated clusters, made up of the minimum number of propulsion units, then such a system can provide attitude control and stationkeeping for most vehicles. A distributed propulsion system is characterized by more numerous propulsion units in a regularly distributed arrangement. Various proposed large space systems are reviewed and it is concluded that centralized auxiliary propulsion is best suited to vehicles with a relatively rigid core. These vehicles may carry a number of flexible or movable appendages. A second group, consisting of one or more large flexible flat plates, may need distributed propulsion for shape control. There is a third group, consisting of vehicles built up from multiple shuttle launches, which may be forced into a distributed system because of the need to add additional propulsion units as the vehicles grow. The effects of distributed propulsion on a beam-like structure were examined. The deflection of the structure under both translational and rotational thrusts is shown as a function of the number of equally spaced thrusters. When two thrusters only are used it is shown that location is an important parameter. The possibility of using distributed propulsion to achieve minimum overall system weight is also examined. Finally, an examination of the active damping by distributed propulsion is described.

Centrally Banked Cryptocurrencies

OpenAIRE

Danezis, George; Meiklejohn, Sarah

2015-01-01

Current cryptocurrencies, starting with Bitcoin, build a decentralized blockchain-based transaction ledger, maintained through proofs-of-work that also generate a monetary supply. Such decentralization has benefits, such as independence from national political control, but also significant limitations in terms of scalability and computational cost. We introduce RSCoin, a cryptocurrency framework in which central banks maintain complete control over the monetary supply, but rely on a distribut...

Centrally Banked Cryptocurrencies

OpenAIRE

Danezis, G.; Meiklejohn, S.

2016-01-01

Current cryptocurrencies, starting with Bitcoin, build a decentralized blockchain-based transaction ledger, maintained through proofs-of-work that also serve to generate a monetary supply. Such decentralization has benefits, such as independence from national political control, but also significant limitations in terms of computational costs and scalability. We introduce RSCoin, a cryptocurrency framework in which central banks maintain complete control over the monetary supply, but rely on...

A centralized audio presentation manager

Energy Technology Data Exchange (ETDEWEB)

Papp, A.L. III; Blattner, M.M.

1994-05-16

The centralized audio presentation manager addresses the problems which occur when multiple programs running simultaneously attempt to use the audio output of a computer system. Time dependence of sound means that certain auditory messages must be scheduled simultaneously, which can lead to perceptual problems due to psychoacoustic phenomena. Furthermore, the combination of speech and nonspeech audio is examined; each presents its own problems of perceptibility in an acoustic environment composed of multiple auditory streams. The centralized audio presentation manager receives abstract parameterized message requests from the currently running programs, and attempts to create and present a sonic representation in the most perceptible manner through the use of a theoretically and empirically designed rule set.

Alternative Fuels Data Center: Central Ohio Turns Trash Into Natural Gas

Science.gov (United States)

Central Ohio Turns Trash Into Natural Gas to someone by E-mail Share Alternative Fuels Data Center : Central Ohio Turns Trash Into Natural Gas on Facebook Tweet about Alternative Fuels Data Center: Central Ohio Turns Trash Into Natural Gas on Twitter Bookmark Alternative Fuels Data Center: Central Ohio Turns

[The unnecessary application of central venous catheterization in surgical patients].

Science.gov (United States)

Uemura, Keiko; Inoue, Satoki; Kawaguchi, Masahiko

2018-04-06

Perioperative physicians occasionally encounter situations where central venous catheters placed preoperatively turn out to be unnecessary. The purpose of this retrospective study is to identify the unnecessary application of central venous catheter placement and determine the factors associated with the unnecessary application of central venous catheter placement. Using data from institutional perioperative central venous catheter surveillance, we analysed data from 1,141 patients who underwent central venous catheter placement. We reviewed the central venous catheter registry and medical charts and allocated registered patients into those with the proper or with unnecessary application of central venous catheter according to standard indications. Multivariate analysis was used to identify factors associated with the unnecessary application of central venous catheter placement. In 107 patients, representing 9.38% of the overall population, we identified the unnecessary application of central venous catheter placement. Multivariate analysis identified emergencies at night or on holidays (odds ratio [OR] 2.109, 95% confidence interval [95% CI] 1.021-4.359), low surgical risk (OR=1.729, 95% CI 1.038-2.881), short duration of anesthesia (OR=0.961/10min increase, 95% CI 0.945-0.979), and postoperative care outside of the intensive care unit (OR=2.197, 95% CI 1.402-3.441) all to be independently associated with the unnecessary application of catheterization. Complications related to central venous catheter placement when the procedure consequently turned out to be unnecessary were frequently observed (9/107) compared with when the procedure was necessary (40/1034) (p=0.032, OR=2.282, 95% CI 1.076-4.842). However, the subsequent multivariate logistic model did not hold this significant difference (p=0.0536, OR=2.115, 95% CI 0.988-4.526). More careful consideration for the application of central venous catheter is required in cases of emergency surgery at night or on

Endogenous Central Bank Information and the Optimal Degree of Transparency

OpenAIRE

Romain Baeriswyl

2011-01-01

As a policymaker, the central bank both observes and shapes the economy. The central bank scrutinizes market activity to assess the state of the economy, and its policy strongly shapes market outcomes. When transparency allows the central bank to shape the economy more effectively, it may also cause the informational role of the economic aggregate to deteriorate. This paper presents a simple model to capture the endogenous nature of central bank information and to address welfare issues. Firs...

CMS Central Hadron Calorimeter

OpenAIRE

Budd, Howard S.

2001-01-01

We present a description of the CMS central hadron calorimeter. We describe the production of the 1996 CMS hadron testbeam module. We show the results of the quality control tests of the testbeam module. We present some results of the 1995 CMS hadron testbeam.

Financial Independence of Central Bank through the Balance Sheet Prism

Directory of Open Access Journals (Sweden)

Ivanović Valentina

2014-05-01

Full Text Available The main reason for central bank independence lies in the fact that it is necessary to clearly distinguish spending money from the ability of making money. Independence of central banks is now a characteristic of almost all developed and highly industrialized countries. In this respect, it represents an essential part of the overall economic reality of these countries. Over the past decade or somewhat earlier, the issue of importance of central bank independence has been raised in developing countries, making the institutional, functional, personal and financial independence of central banks current topics for consideration. The key reason for the growing attention to financial independence of central banks is due to the effects of the global financial crisis on their balance sheets and therefore the challenges related to achieving the basic goals of the functioning of central banks - financial stability and price stability.

21 CFR 882.5550 - Central nervous system fluid shunt and components.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Central nervous system fluid shunt and components... Central nervous system fluid shunt and components. (a) Identification. A central nervous system fluid... central nervous system to an internal delivery site or an external receptacle for the purpose of relieving...

75 FR 12562 - Central Utah Project Completion Act

Science.gov (United States)

2010-03-16

...-- Water and Science; Utah Reclamation Mitigation and Conservation Commission; and the Central Utah Water... Commission (Mitigation Commission), and the Central Utah Water Conservancy District (District), as Joint Lead... Diamond Fork System Final Supplement to the Diamond Fork Power System Final Environmental Impact Statement...

Central areolar choroidal dystrophy with associated dominant drusen

Directory of Open Access Journals (Sweden)

Julie Rodman

2013-04-01

Conclusion: Central areolar choroidal dystrophy normally presents without drusen. However, in patients manifesting a specific mutation, central areolar choridal dystrophy may present in conjunction with drusen. It appears that the Arg142Trp mutation is one of the factors predisposing to drusen formation.

Human Conservation in Central America, Summary of a Conference (Guatemala, Central America).

Science.gov (United States)

Conservation Foundation, Washington, DC.

This booklet is a resume consisting chiefly of extracts from papers that were presented at a conference on Human Conservation in Central America, held in Guatemala in 1965, as well as from discussions that took place during the conferences. With cooperation of numerous organizations and guidance from the Conservation Foundation, a discussion of…

Autofluorescencia de fondo en pacientes con coriorretinopatía serosa central Fundus autofluorescence in patients with central serous chorioretinopathy

Directory of Open Access Journals (Sweden)

Eva R Santana Alas

2010-01-01

Full Text Available OBJETIVO: Describir las características de la autofluorescencia de fondo en pacientes con coriorretinopatía serosa central y determinar su relación con las alteraciones funcionales y anatómicas de la región macular. MÉTODOS: Estudio descriptivo, transversal en 21 ojos (21 pacientes con coriorretinopatia serosa central en diferentes estadios evolutivos. Se identificó el patrón de autofluorescencia en el área de desprendimiento neurosensorial, se usó el angiógrafo retinal de Heidelberg a 30°. Con la tomografía de coherencia óptica, se midió el grosor macular central y se describieron los cambios anatómicos. A 12 de los pacientes se les realizó angiografía fluoresceínica en el Angiógrafo Retinal de Heidelberg. RESULTADOS: Se encontró hipoautofluorescencia en el 51,90 %, hiperautofluorescencia en el 42,86 %; coexisten ambos en el 4,76 %. No hubo diferencia significativa entre la hiperautofluorescencia y la hipoautofluorescencia en cuanto a agudeza visual mejor corregida (media de 0,43 y 0,49, respectivamente; p= 0,184, ni respecto al grosor macular central (media de 371,3 µm y 388,1 µm, respectivamente; p= 0,867, pero sí entre el tiempo de evolución y el patrón de autofluorescencia, (p= 0, 023. En ojos con hiperautofluorescencia se observó por tomografía de coherencia óptica irregularidad en capas externas y en epitelio pigmentario de la retina. El 83,3 % de los casos que requirieron angiografía fluoresceínica presentaron hiperfluorescencia que coincidió con la hipoautofluorescencia del sitio de fuga. CONCLUSIONES: En la coriorretinopatía serosa central se encuentran diferentes patrones de autofluorescencia, los que reflejan cambios en la retina externa y epitelio pigmentario de la retina. La autofluorescencia puede ayudar a identificar el sitio de difusión focal en el epitelio pigmentario de la retina.OBJECTIVES: To describe the peculiarities of the Fundus Autofluorecense in patiens with Central Serous

The European Central Bank : Independence, accountability and strategy: A review

NARCIS (Netherlands)

De Haan, J

1997-01-01

This paper reviews research on central banking and monetary policy, with special emphasis on the position of the future European Central Bank. Nowadays, it is often thought that an independent central bank with an explicit mandate to aim for price stability constitutes an important institutional

Theories of central engine for long gamma-ray bursts

Science.gov (United States)

Nagataki, Shigehiro

2018-02-01

Long GRBs are the most powerful explosions in the universe since the Big Bang. At least, some fraction of long GRBs are born from the death of massive stars. Likewise, only some fraction of massive stars that satisfy additional special conditions explode as long GRBs associated with supernovae/hypernovae. In this paper, we discuss the explosion mechanism of long GRBs associated with hypernovae: ‘the central engine of long GRBs’. The central engine of long GRBs is very different from that of core-collapse supernovae, although the mechanism of the engine is still not firmly established. In this paper, we review theoretical studies of the central engine of long GRBs. First, we discuss possible progenitor stars. Then several promising mechanisms of the central engine—such as black hole and magnetar formation—will be reviewed. We will also mention some more exotic models. Finally, we describe prospects for future studies of the central engine of long GRBs.

Central structure preservation of the reversal sign

International Nuclear Information System (INIS)

Chen, C.J.

1999-01-01

We report serial changes of central structure preservation of the reversal sign in a case of child abuse. The serial CT images show that the relatively spared attenuation at the basal ganglia, thalami, and posterior fossa develops before the occurrence of transtentorial herniation. This finding makes the theory that central preservation of the reversal sign is due to pressure relief after transtentorial herniation less convincible. (orig.)

Central structure preservation of the reversal sign

Energy Technology Data Exchange (ETDEWEB)

Chen, C.J. [Dept. of Diagnostic Radiology, Chang Gung Memorial Hospital, Taipei (Taiwan)

1999-12-01

We report serial changes of central structure preservation of the reversal sign in a case of child abuse. The serial CT images show that the relatively spared attenuation at the basal ganglia, thalami, and posterior fossa develops before the occurrence of transtentorial herniation. This finding makes the theory that central preservation of the reversal sign is due to pressure relief after transtentorial herniation less convincible. (orig.)

"Delineamento duplo central composto com 29 pontos" Double central composite design with 29 points

Directory of Open Access Journals (Sweden)

Armando Conagin

1979-01-01

Full Text Available O delineamento duplo central composto com 29 pontos representa uma extensão do delineamento central composto e foi desenvolvido para o estudo de três fatores em mais de três níveis. Essencialmente, consta de dois fatoriais 2³ (níveis 1 e B, de duas estrelas (níveis a e 2alfa e de um ponto no centro do delineamento. É mostrada a origem do delineamento, o tipo não ortogonal, completamente casualizado, o tipo ortogonal completamente casualizado e o ortogonal divisível em dois blocos. No primeiro deles, seriam estudados três fatores em cinco níveis (-2, -1,-0, + 1 e +2; no segundo, três fatores em nove níveis (-3,02; -2,00; -1,51; -1,00; 0,00; + 1,00; +1,51; +2,00 e +3.02 e, no terceiro, três fatores nos nove níveis seguintes (-7,262; -4,391; -3,631; -1,000; 0,000; +1,000; +3,631; +4,391 e +7,262. É apresentado também um exemplo do último delineamento. com sua análise respectiva. De acordo com o critério de Box & Wilson (2, esse último delineamento é mais eficiente que o fatorial 3 x 3 x 3 divisível em blocos de nove. Os três delineamentos podem ser empregados em programas de adubação visando ao estudo de macronutrientes com vistas à recomendação das doses ótimas de fertilizantes que possibilitem a maximização do lucro obtido e, ainda, em outras áreas da pesquisa científica em que se deseja a avaliação da superfície de resposta, o estudo dos seus pontos extremos, etc.The double central composite design with 29 points rcpresents an extension of the central composite design and was developed for the study of three factors in more than three levels. Essentially it is composed of two 2³ factorials (levels 1 and B, of two stars (levels alpha and 2alpha and of one central point. In the present paper the origin of the design, the double central composite completely randomized not orthogonal in 5 levels (-2, -1, 0, +1 and +2, the completely randomized design, orthogonal, in nine levels (-3.02; -2.00; -1.51; -1.00; 0

Ecodesign in Central America

NARCIS (Netherlands)

Crul, M.R.M.

2003-01-01

This PhD thesis describes and analyses the change process started by the Ecodesign project in Central America, executed between 1998 and 2002. The project started using the concept and praxis developed in Europe. Nine ecodesign projects were performed in industry, and ecodesign was introduced to

41 CFR 105-56.027 - Centralized salary offset computer match.

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Centralized salary... Services Administration 56-SALARY OFFSET FOR INDEBTEDNESS OF FEDERAL EMPLOYEES TO THE UNITED STATES Centralized Salary Offset (CSO) Procedures-GSA as Paying Agency § 105-56.027 Centralized salary offset...

41 CFR 105-56.017 - Centralized salary offset computer match.

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Centralized salary... Services Administration 56-SALARY OFFSET FOR INDEBTEDNESS OF FEDERAL EMPLOYEES TO THE UNITED STATES Centralized Salary Offset (CSO) Procedures-GSA as Creditor Agency § 105-56.017 Centralized salary offset...

HANFORD SITE CENTRAL PLATEAU CLEANUP COMPLETION STRATEGY

International Nuclear Information System (INIS)

Bergman, T.B.

2011-01-01

Cleanup of the Hanford Site is a complex and challenging undertaking. The U.S. Department of Energy (DOE) has developed a comprehensive vision for completing Hanford's cleanup mission including transition to post-cleanup activities. This vision includes 3 principle components of cleanup: the ∼200 square miles ofland adjacent to the Columbia River, known as the River Corridor; the 75 square miles of land in the center of the Hanford Site, where the majority of the reprocessing and waste management activities have occurred, known as the Central Plateau; and the stored reprocessing wastes in the Central Plateau, the Tank Wastes. Cleanup of the River Corridor is well underway and is progressing towards completion of most cleanup actions by 2015. Tank waste cleanup is progressing on a longer schedule due to the complexity of the mission, with construction of the largest nuclear construction project in the United States, the Waste Treatment Plant, over 50% complete. With the progress on the River Corridor and Tank Waste, it is time to place increased emphasis on moving forward with cleanup of the Central Plateau. Cleanup of the Hanford Site has been proceeding under a framework defmed in the Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement). In early 2009, the DOE, the State of Washington Department of Ecology, and the U.S. Environmental Protection Agency signed an Agreement in Principle in which the parties recognized the need to develop a more comprehensive strategy for cleanup of the Central Plateau. DOE agreed to develop a Central Plateau Cleanup Completion Strategy as a starting point for discussions. This DOE Strategy was the basis for negotiations between the Parties, discussions with the State of Oregon, the Hanford Advisory Board, and other Stakeholder groups (including open public meetings), and consultation with the Tribal Nations. The change packages to incorporate the Central Plateau Cleanup Completion Strategy were signed by the

Peripheral cholangio carcimona with central abscess: one case report

International Nuclear Information System (INIS)

Rho, Taek Soo; Jung, Hoe Seok; Park, Cheol Min; Cha, In Ho

1993-01-01

The authors experienced one case of peripheral cholangio carcinoma with central abscess. CT and ultrasound demonstrate a well defined fluid collection with smooth wall in central portion of mass in left hepatic lobe.Needle aspiration revealed 150ml of pus with chocolate color. Follow-up ultrasound 2 weeks after antibiotics therapy showed fluid collection again. Fine needle aspiration biopsy was performed from a surrounding solid portion of a fluid collection area, and pathologic diagnosis was adenocarcinoma. In case of recurrent abscess or necrosis, we recommend fine needle aspiration biopsy from a central fluid collection area as well as surrounding solid portion of mass for the possibility of central abscess in peripheral cholangio carcinoma of the liver

Peripheral cholangio carcimona with central abscess: one case report

Energy Technology Data Exchange (ETDEWEB)

Rho, Taek Soo; Jung, Hoe Seok; Park, Cheol Min; Cha, In Ho [Korea University College of Medicine, Seoul (Korea, Republic of)

1993-12-15

The authors experienced one case of peripheral cholangio carcinoma with central abscess. CT and ultrasound demonstrate a well defined fluid collection with smooth wall in central portion of mass in left hepatic lobe.Needle aspiration revealed 150ml of pus with chocolate color. Follow-up ultrasound 2 weeks after antibiotics therapy showed fluid collection again. Fine needle aspiration biopsy was performed from a surrounding solid portion of a fluid collection area, and pathologic diagnosis was adenocarcinoma. In case of recurrent abscess or necrosis, we recommend fine needle aspiration biopsy from a central fluid collection area as well as surrounding solid portion of mass for the possibility of central abscess in peripheral cholangio carcinoma of the liver

Central Tendon Injuries of Hamstring Muscles: Case Series of Operative Treatment.

Science.gov (United States)

Lempainen, Lasse; Kosola, Jussi; Pruna, Ricard; Puigdellivol, Jordi; Sarimo, Janne; Niemi, Pekka; Orava, Sakari

2018-02-01

As compared with injuries involving muscle only, those involving the central hamstring tendon have a worse prognosis. Limited information is available regarding the surgical treatment of central tendon injuries of the hamstrings. To describe the operative treatment and outcomes of central tendon injuries of the hamstrings among athletes. Case series; Level of evidence, 4. Eight athletes (6 top level, 2 recreational) with central hamstring tendon injuries underwent magnetic resonance imaging and surgical treatment. The indication for surgery was recurrent (n = 6) or acute (n = 2) central hamstring tendon injury. All patients followed the same postoperative rehabilitation protocol, and return to play was monitored. Magnetic resonance imaging found a central tendon injury in all 3 hamstring muscles (long head of the biceps femoris, semimembranosus, and semitendinosus) with disrupted tendon ends. In acute and recurrent central tendon injuries, full return to play was achieved at 2.5 to 4 months. There were no adverse events during follow-up. Central tendon injuries of the hamstrings can be successfully repaired surgically after acute and recurrent ruptures.

Central Tendon Injuries of Hamstring Muscles: Case Series of Operative Treatment

Science.gov (United States)

Lempainen, Lasse; Kosola, Jussi; Pruna, Ricard; Puigdellivol, Jordi; Sarimo, Janne; Niemi, Pekka; Orava, Sakari

2018-01-01

Background: As compared with injuries involving muscle only, those involving the central hamstring tendon have a worse prognosis. Limited information is available regarding the surgical treatment of central tendon injuries of the hamstrings. Purpose: To describe the operative treatment and outcomes of central tendon injuries of the hamstrings among athletes. Study Design: Case series; Level of evidence, 4. Methods: Eight athletes (6 top level, 2 recreational) with central hamstring tendon injuries underwent magnetic resonance imaging and surgical treatment. The indication for surgery was recurrent (n = 6) or acute (n = 2) central hamstring tendon injury. All patients followed the same postoperative rehabilitation protocol, and return to play was monitored. Results: Magnetic resonance imaging found a central tendon injury in all 3 hamstring muscles (long head of the biceps femoris, semimembranosus, and semitendinosus) with disrupted tendon ends. In acute and recurrent central tendon injuries, full return to play was achieved at 2.5 to 4 months. There were no adverse events during follow-up. Conclusion: Central tendon injuries of the hamstrings can be successfully repaired surgically after acute and recurrent ruptures. PMID:29479545

Central venous stenosis among hemodialysis patients is often not associated with previous central venous catheters.

Science.gov (United States)

Kotoda, Atsushi; Akimoto, Tetsu; Kato, Maki; Kanazawa, Hidenori; Nakata, Manabu; Sugase, Taro; Ogura, Manabu; Ito, Chiharu; Sugimoto, Hideharu; Muto, Shigeaki; Kusano, Eiji

2011-01-01

It is widely assumed that central venous stenosis (CVS) is most commonly associated with previous central venous catheterization among the chronic hemodialysis (HD) patients. We evaluated the validity of this assumption in this retrospective study. The clinical records from 2,856 consecutive HD patients with vascular access failure during a 5-year period were reviewed, and a total of 26 patients with symptomatic CVS were identified. Combined with radiological findings, their clinical characteristics were examined. Only seven patients had a history of internal jugular dialysis catheterization. Diagnostic multidetector row computed tomography angiography showed that 7 of the 19 patients with no history of catheterization had left innominate vein stenosis due to extrinsic compression between the sternum and arch vessels. These patients had a shorter period from the time of creation of the vascular access to the initial referral (9.2 ± 7.6 months) than the rest of the patients (35.5 ± 18.6 months, p = 0.0017). Our findings suggest that cases without a history of central venous catheterization may not be rare among the HD patients with symptomatic CVS. However, those still need to be confirm by larger prospective studies of overall chronic HD patients with symptomatic CVS.

The EMMA Non-scaling FFAG

CERN Document Server

Edgecock, Thomas; Clarke, James; Griffiths, Stephen; Hill, Clive; Jamison, Steven; Jones, James; Kalinin, Alexander; Marinov, Kiril; Marks, Neil; McIntosh, Peter; Muratori, Bruno; Orrett, Joseph; Saveliev, Yuri; Shepherd, Ben; Smith, Robert; Smith, Susan; Tzenov, Stephan; Wheelhouse, Alan; Berg, J. Scott; Bliss, Neil; Martlew, Brian; White, Christopher; Craddock, Michael; Crisp, James; Johnstone, Carol; Giboudot, Yoel; Keil, Eberhard; Kelliher, David; Machida, Shinji; Koscielniak, Shane; Meot, Francois; Pasternak, Jaroslaw; Sheehy, Suzanne; Yokoi, Takeichiro

2010-01-01

The Elec­tron Model for Many Ap­pli­ca­tions (EMMA) will be the World's first non-scal­ing FFAG and is under con­struc­tion at the STFC Dares­bury Lab­o­ra­to­ry in the UK. Con­struc­tion is due for com­ple­tion in March 2010 and will be fol­lowed by com­mis­sion­ing with beam and a de­tailed ex­per­i­men­tal pro­gramme to study the func­tion­ing of this type of ac­cel­er­a­tor. This paper will give an overview of the mo­ti­va­tion for the pro­ject and de­scribe the EMMA de­sign and hard­ware. The first re­sults from com­mis­sion­ing will be pre­sent­ed in a sep­a­rate paper.

Clinical and radiological characteristics of central pulmonary adenocarcinoma: a comparison with central squamous cell carcinoma and small cell lung cancer and the impact on treatment response

Directory of Open Access Journals (Sweden)

Wang Z

2018-05-01

Full Text Available Zhe Wang,1,2 Minghuan Li,2 Yong Huang,3 Li Ma,3 Hui Zhu,2 Li Kong,2 Jinming Yu2 1School of Medicine, Shandong University, Jinan, Shandong, China; 2Department of Radiation Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Jinan, Shandong, China; 3Department of Radiology, Shandong Cancer Hospital Affiliated to Shandong University, Jinan, Shandong, China Purpose: The proportion of central pulmonary adenocarcinoma (ADC in central-type lung cancer has been gradually increasing due to the overall increasing incidence of pulmonary ADC. But the clinical and radiological characteristics of central ADCs remain unclear. In this study, we compared the clinical and radiological characteristics of central ADCs with those of small cell lung cancers (SCLCs and squamous cell carcinomas (SQCCs and investigated the impact of these characteristics on patients’ treatment response. Patients and methods: The medical records of 302 consecutive patients with central lung cancer from July 2014 to September 2016 were retrospectively reviewed. There were 99 patients with ADC, 95 with SQCC and 108 with SCLC. Computed tomography images were interpreted by two radiologists. Treatment response was determined by Response Evaluation Criteria In Solid Tumors 1.1. Results: Univariate analyses found that younger age, female sex, no history of smoking, higher levels of carcinoembryonic antigen (CEA, contralateral hilum lymphadenopathy, contralateral lung metastasis, pleural nodules and pleural metastasis to the interlobular fissure were significantly correlated with central ADC. Multivariate logistic regression analyses revealed that compared with central SQCC, female sex, younger age, no history of smoking, higher levels of CEA and contralateral hilum lymphadenopathy were the significantly independent indicators of central pulmonary ADC. Furthermore, compared with central SCLC, younger age, higher levels of CEA and cytokeratin 19 fragment (Cyfra21-1, lower

Least-cost network evaluation of centralized and decentralized contributions to global electrification

International Nuclear Information System (INIS)

Levin, Todd; Thomas, Valerie M.

2012-01-01

The choice between centralized and decentralized electricity generation is examined for 150 countries as a function of population distribution, electricity consumption, transmission cost, and the cost difference between decentralized and centralized electricity generation. A network algorithm is developed to find the shortest centralized transmission network that spans a given fraction of the population in a country. The least-cost combination of centralized and decentralized electricity that serves the country is determined. Case studies of Botswana, Uganda, and Bangladesh illustrate situations that are more and less suited for decentralized electrification. Specific maps for centralized and decentralized generation are presented to show how the least-cost option varies with the relative costs of centralized and decentralized generation and transmission cost. Centralized and decentralized fractions are calculated for 150 countries. For most of the world's population, centralized electricity is the least-cost option. For a number of countries, particularly in Africa, substantial populations and regions may be most cost-effectively served by decentralized electricity. - Highlights: ► Centralized and decentralized electrification are compared for 150 countries. ► A cost-optimized network algorithm finds the least-cost electrification system. ► Least-cost infrastructures combine centralized and decentralized portions. ► For most people, centralized electricity is cheapest option. ► In much of Africa, decentralized electricity may be cheaper than centralized.

Optimizing the distribution of centralizers; Otimizacao da distribuicao de centralizadores

Energy Technology Data Exchange (ETDEWEB)

Fonseca, Carlos Fernando H; Salies, Jacques Braile [PETROBRAS, XX (Brazil). Dept. de Perfuracao. Div. de Revestimento de Cimentacao

1990-12-31

There are two procedures for the distribution of centralizers on casing: rules of thumb for vertical wells and the well-know theoretical model developed in API SPEC 10D. This paper presents a new approach for the disposition of centralizers. Casing deflection is modeled more realistically than in the API algorithm, using better boundary conditions. A computer application was developed to integrate information on hole trajectory, casing properties and the performance of centralizers, in order to optimize centralizer spacing. The paper also presents a few comparative examples, and the results obtained are less conservative than those of the API model, thus reducing the number of centralizers to be run in a particular well. (author) 6 refs., 7 figs., 3 tabs.

Optimizing the distribution of centralizers; Otimizacao da distribuicao de centralizadores

Energy Technology Data Exchange (ETDEWEB)

Fonseca, Carlos Fernando H.; Salies, Jacques Braile [PETROBRAS, XX (Brazil). Dept. de Perfuracao. Div. de Revestimento de Cimentacao

1989-12-31

There are two procedures for the distribution of centralizers on casing: rules of thumb for vertical wells and the well-know theoretical model developed in API SPEC 10D. This paper presents a new approach for the disposition of centralizers. Casing deflection is modeled more realistically than in the API algorithm, using better boundary conditions. A computer application was developed to integrate information on hole trajectory, casing properties and the performance of centralizers, in order to optimize centralizer spacing. The paper also presents a few comparative examples, and the results obtained are less conservative than those of the API model, thus reducing the number of centralizers to be run in a particular well. (author) 6 refs., 7 figs., 3 tabs.