WorldWideScience

Sample records for central crete based

  1. River profile response to normal fault growth and linkage: an example from the Hellenic forearc of south-central Crete, Greece

    Science.gov (United States)

    Gallen, Sean F.; Wegmann, Karl W.

    2017-02-01

    Topography is a reflection of the tectonic and geodynamic processes that act to uplift the Earth's surface and the erosional processes that work to return it to base level. Numerous studies have shown that topography is a sensitive recorder of tectonic signals. A quasi-physical understanding of the relationship between river incision and rock uplift has made the analysis of fluvial topography a popular technique for deciphering relative, and some argue absolute, histories of rock uplift. Here we present results from a study of the fluvial topography from south-central Crete, demonstrating that river longitudinal profiles indeed record the relative history of uplift, but several other processes make it difficult to recover quantitative uplift histories. Prior research demonstrates that the south-central coastline of Crete is bound by a large ( ˜ 100 km long) E-W striking composite normal fault system. Marine terraces reveal that it is uplifting between 0.1 and 1.0 mm yr-1. These studies suggest that two normal fault systems, the offshore Ptolemy and onshore South-Central Crete faults, linked together in the recent geologic past (ca. 0.4-1 My BP). Fault mechanics predict that when adjacent faults link into a single fault the uplift rate in footwalls of the linkage zone will increase rapidly. We use this natural experiment to assess the response of river profiles to a temporal jump in uplift rate and to assess the applicability of the stream power incision model to this setting. Using river profile analysis we show that rivers in south-central Crete record the relative uplift history of fault growth and linkage as theory predicts that they should. Calibration of the commonly used stream power incision model shows that the slope exponent, n, is ˜ 0.5, contrary to most studies that find n ≥ 1. Analysis of fluvial knickpoints shows that migration distances are not proportional to upstream contributing drainage area, as predicted by the stream power incision model

  2. The Sedimentary History of Southern Central Crete: Implications for Neogene Uplift

    Science.gov (United States)

    Kröger, K.; Brachert, T. C.; Reuter, M.

    2003-04-01

    1000m since the Early Pliocene. At the Central Iraklion Ridge that separates the Messara and Iraclion Basins a similar history is indicated for the Psiloritis Mountains by fault movements within Neogene near shore sediments and their subsequent drowning. A structural model of the Neogene evolution of Crete therefore has to explain successive phases of uplift and subsidence in an over all extensional setting only slightly oblique to the modern direction of convergence between Africa and the Aegean microplate.

  3. U–Pb zircon and biostratigraphic data of high‐pressure/ low‐temperature metamorphic rocks of the Talea Ori : tracking the Paleotethys suture in central Crete, Greece

    NARCIS (Netherlands)

    Zulauf, G.; Dörr, W.; Krahl, J.; Lahaye, Y.; Chatzaras, V.; Xypolias, P.

    2016-01-01

    Inherited deformation microfabrics of detrital quartz grains and U–Pb (Laser ablation (LA)-ICPMS and ID TIMS) ages of detrital zircons separated from the Phyllite–Quartzite Unit s.l. of the Talea Ori, central Crete, suggest strikingly different source rocks. Albite gneiss of the lower Rogdia Beds

  4. Minoan Crete

    DEFF Research Database (Denmark)

    Sarri, Kalliopi

    1998-01-01

    to social structures, customs, and economic life. Thus, we now speak of palatial society and economy. In comparison with other early civilizations, Minoan civilization expresses an unprecedented sense of freedom and lightness which is expressed mainly in art and could be attributed to the laxity...... of the administrative system. However, after a more careful study of the society, we see that specific and probably strict social rules were imposed in Minoan Crete while religion dominated almost every activity and expression. Minoan civilization covers chronologically the passage from Prehistory to Proto...

  5. U-Pb zircon and biostratigraphic data of high-pressure/low-temperature metamorphic rocks of the Talea Ori: tracking the Paleotethys suture in central Crete, Greece

    Science.gov (United States)

    Zulauf, G.; Dörr, W.; Krahl, J.; Lahaye, Y.; Chatzaras, V.; Xypolias, P.

    2016-10-01

    Inherited deformation microfabrics of detrital quartz grains and U-Pb (Laser ablation (LA)-ICPMS and ID TIMS) ages of detrital zircons separated from the Phyllite-Quartzite Unit s.l. of the Talea Ori, central Crete, suggest strikingly different source rocks. Albite gneiss of the lower Rogdia Beds includes Cambrian and Neoproterozoic rounded zircons with main U-Pb age peaks at 628 and 988 Ma. These and minor Paleoproterozoic and Archean peaks, together with the lack of Variscan-aged and Mesoproterozoic zircons, are similar to the age spectra obtained from the Phyllite-Quartzite Unit s.str. of the Peloponnesus and eastern Crete and from the Taurides. All of these zircons should be derived from the northeastern passive margin of Gondwana (Cimmeria). Metatuffites of the uppermost Rogdia Beds and metasandstone of Bali beach, on the other hand, include euhedral detrital zircons displaying a Variscan U-Pb age spectra at ca. 300 Ma with concordia ages at 291 ± 3, 300 ± 1 Ma (Rogdia) and 286 ± 3, 300 ± 3, 313 ± 2 Ma (Bali). Both types of metasediments and their zircons are similar to those of the pre-Alpine basement and overlying Tyros Beds of eastern Crete, revealing a provenance at the southern active margin of Laurasia. Thus, in central Crete the Paleotethys suture should be situated inside the Rogdia Beds. Magmatic zircons separated from a rhyolite boulder of the lower Achlada Beds yielded a concordant U-Pb zircon age at 242 ± 2 Ma placing a maximum age for the deposition of the (meta)conglomerate from which the boulder was collected. This age is compatible with an Olenekian-early Anisian age of the underlying Vasilikon marble suggested by new findings of the foraminifera Meandrospira aff. pusilla. Both the Achlada Beds and the Vasilikon marble can be attributed to the lower Tyros Beds of eastern Crete. The Alpine deformation led to a pervasive mylonitic foliation, which is affecting most of the studied rocks. This foliation results from D2 top

  6. Neotectonic control on drainage systems: GIS-based geomorphometric and morphotectonic assessment for Crete, Greece

    Science.gov (United States)

    Argyriou, Athanasios V.; Teeuw, Richard M.; Soupios, Pantelis; Sarris, Apostolos

    2017-11-01

    Geomorphic indices can be used to examine the geomorphological and tectonic processes responsible for the development of the drainage basins. Such indices can be dependent on tectonics, erosional processes and other factors that control the morphology of the landforms. The inter-relationships between geomorphic indices can determine the influence of regional tectonic activity in the shape development of drainage basins. A Multi-Criteria Decision Analysis (MCDA) procedure has been used to perform an integrated cluster analysis that highlights information associated with the dominant regional tectonic activity. Factor Analysis (FA) and Analytical Hierarchy Process (AHP) were considered within that procedure, producing a representation of the distributed regional tectonic activity of the drainage basins studied. The study area is western Crete, located in the outer fore-arc of the Hellenic subduction zone, one of the world's most tectonically active regions. The results indicate that in the landscape evolution of the study area (especially the western basins) tectonic controls dominate over lithological controls.

  7. Pliocene benthonic foraminifera from homogeneous and laminated marls on Crete

    NARCIS (Netherlands)

    Jonkers, H.A.

    1984-01-01

    In the Pliocene, the paleogeography of central Crete consisted of a number of basins which were filled by predominantly marly sediments. In the sedimentary sequence numerous laminated sapropelic intercalations can be observed. At a higher stratigraphic level diatomaceous laminites appear.

  8. Tamarix minoa (Tamaricaceae), a new species from the island of Crete (Greece) based on morphological and plastid molecular sequence data

    Science.gov (United States)

    Tamarix minoa is described from material collected on the S Aegean island of Crete (Kriti), Greece. A morphological comparison with the species considered to be closest, T. africana and T. hampeana, is provided. An original illustration showing the main morphological characters of the new species is...

  9. The Hellenic Seismological Network Of Crete (HSNC): Validation and results of the 2013 aftershock sequences

    Science.gov (United States)

    Chatzopoulos, Georgios; Papadopoulos, Ilias; Vallianatos, Filippos

    2015-04-01

    The number and quality of seismological networks in Europe has increased in the past decades. Nevertheless, the need for localized networks monitoring areas of great seismic and scientific interest is constant. Hellenic Seismological Network of Crete (HSNC) covers this need for the vicinity of the South Aegean Sea and Crete Island. In the present work with the use of Z-map software (www.seismo.ethz.ch) the spatial variability of Magnitude of Completeness (Mc) is calculated from HSNC's manual analysis catalogue of events for the period 2011 until today, proving the good coverage of HSNC in the areas. Furthermore the 2013, South Aegean seismicity where two large shallow earthquakes occurred in the vicinity of Crete Island, is discussed. The first event takes place on 15th June 2013 in the front of the Hellenic Arc, south from central Crete, while the second one on 12th October, 2013 on the western part of Crete. The two main shocks and their aftershock sequences have been relocated with the use of hypoinverse earthquake location software and an appropriate crust model. The HSNC identified more than 500 and 300 aftershocks respectively followed after the main events. The detailed construction of aftershocks catalogue permits the applicability of modern theories based on complexity sciences as described recently in the frame of non extensive statistical physics. In addition site effects in the stations locations are presented using event and noise recordings. This work was implemented through the project IMPACT-ARC in the framework of action "ARCHIMEDES III-Support of Research Teams at TEI of Crete" (MIS380353) of the Operational Program "Education and Lifelong Learning" and is co-financed by the European Union (European Social Fund) and Greek national funds References A. Tzanis and F. Vallianatos, "Distributed power-law seismicity changes and crustal deformation in the EW Hellenic Arc", Natural Hazards and Earth Systems Sciences, 3, 179-195, 2003 F. Vallianatos, G

  10. Pre-Messinian (Sub-Salt Source-Rock Potential on Back-Stop Basins of the Hellenic Trench System (Messara Basin, Central Crete, Greece

    Directory of Open Access Journals (Sweden)

    Maravelis A.

    2016-01-01

    Full Text Available The Greek part of the Mediterranean Ridge suggests, in terms of its hydrocarbon potential, further frontier exploration. The geological similarities between its prolific portions, within the Cyprus and Egyptian Exclusive Economic Zones, indicate possible recoverable natural gas reserves in its Greek portion. Nevertheless it lacks of systematic frontier exploration although direct petroleum indicators occur. Active mud volcanoes on the Mediterranean Ridge, still emitting concurrently gas and gas hydrates, have not been yet assessed even though are strongly related to hydrocarbon occurrence worldwide (Caspian Sea, Gulf of Mexico, Western African Basin, Trinidad-Tobago, the Nile Cone. For this reason, the source rock potential of the Late Miocene lacustrine deposits on a backstop basin of the Hellenic Trench System (Messara Basin, Crete, Greece, was studied. The obtained pyrolysis data indicate that the containing organic matter is present in sufficient abundance and with good enough quality to be regarded as potential source rocks. The observed type III kerogen suggests gas generation potential. Although indications of higher thermal evolution occur the studied rocks suggest low maturation levels. The biogenic gas seeps in the studied research well further demonstrate the regional gas generation potential.

  11. Gis-based assessment of marine oil spill hazard and environmental vulnerability for the coasts of Crete in South Aegean Sea

    Science.gov (United States)

    Spanoudaki, Katerina; Nikiforakis, Ioannis K.; Kampanis, Nikolaos A.

    2017-04-01

    Developing effective early warning and coordination systems can save thousands of lives and protect people, property and the environment in the event of natural and man-made disasters. In its document "Towards Better Protection of Citizens against Disaster Risks: Strengthening Early Warning Systems in Europe", the Commission points out that it seeks to follow a multi-hazard approach, to develop near real time alert systems, to ensure a near real time dissemination of alerts to Participating States, and to improve its rapid analytical capacity. In this context, the EU project DECATASTROPHIZE (http://decatastrophize.eu/project/) co-financed by the EU Humanitarian Aid and Civil Protection aims to develop a Geospatial Early warning Decision Support System (GE-DSS) to assess, prepare for and respond to multiple and/or simultaneous natural and man-made hazards, disasters, and environmental incidents by using existing models/systems in each partner country (Cyprus, France, Greece, Italy and Spain) in a synergistic way on ONE multi-platform, called DECAT. Specifically, project partners will establish appropriate geo-databases for test areas and use existing hazard models to produce hazard and vulnerability geo-spatial information for earthquakes, landslides, tsunamis, floods, forest fires and marine oil spills. The GE-DSS in will consist of one source code with six geodatabases, i.e., one for each partner and risk data in the respective test area. Each partner organization will be able to manage and monitor its own data/database and their results using Multi-Criteria Decision Analysis (MCDA). The GE-DSS will be demonstrated at the local, regional and national levels through a set of Command Post and Table Top Disaster Exercises. As part of the DECAT GE-DSS, the gis-based geo-database and assessment of marine oil spill hazard and environmental vulnerability for the coasts of Crete in South Aegean Sea are presented here. Environmental Sensitivity Index (ESI) maps are

  12. The Battle of Crete: Hitler's Airborne Gamble

    National Research Council Canada - National Science Library

    Blank, Maria

    2003-01-01

    As Adolf Hitler conquered most of the European continent in 1939-1941, the small island of Crete in the Mediterranean Sea became vital to future operations in the Mediterranean region for both the Axis and Allied powers...

  13. About the Distribution of Metal Objects in Prepalatial Crete

    Directory of Open Access Journals (Sweden)

    Borja Legarra Herrero

    2004-11-01

    Full Text Available Although metal objects have been used as evidence in different interpretations of the socioeconomic changes identified in Prepalatial Crete (c.3100-1900 BC, they constitute an understudied category of material. This paper argues that metal objects on Crete were subject to complex processes regarding the creation of meaning; a more comprehensive appraisal of metal objects on the island may cast new light on these issues. Copper-based, gold, lead and silver objects are investigated from their ore extraction locations outside Crete to their final deposition, linking the different steps of the process of creating an artefact with different layers of meanings for the metal and, subsequently, for the finished objects. This study evaluates differences in the use of metals, with a particular focus on their intra-island depositional patterns. It seeks to identify differences in the roles of metals within Cretan communities as well as regional fashions in the use of metal objects. It is suggested that metals had different characters since their depositional patterns vary, and that people consciously chose certain metals to make specific objects and also used metal objects in different ways, reflecting the socio-economic context for each region.

  14. The woman in Minoic Crete.

    Science.gov (United States)

    Grammatikakis, Ioannis Emm

    2011-07-01

    Minoan Civilization (3000-1150 BC) was the first European civilization on the GREEK island of Crete. Fabulous architectonical constructions like great palaces, wonderful frescoes, and pottery as well as jewellery characterize this amazing civilization. According to all existing descriptions from ancient Greek historians and philosophers like Plato, Thucydides, Strabon but also from all the archaeological findings men and women lived freely and peacefully participating equal in all daily activities, sports, and games. The women were predominating. Minoan women enjoyed a higher social status than other women in later civilizations. Investigation of all the existing data concerning the Minoan culture. Archaeological databases, as well as data from the National University of Athens and other Greek historical institutions were collected and analyzed in order to present the Minoan culture. The Minoic civilization represents a paradigm of a well being society in which the woman played a dominant role. She was the 'mother' but also the 'active woman', who participated in all city activities. Four thousand years later a prototype of a society in which the role of the mother was recognized in an admirably way remains a magnificent paradigm.

  15. Sedimentary facies analysis of a high-frequency, small-scale, peritidal carbonate sequence in the Lower Jurassic of the Tripolis carbonate unit (central western Crete, Greece: Long-lasting emergence and fossil laminar dolocretes horizons

    Directory of Open Access Journals (Sweden)

    Fotini A. Pomoni

    2016-07-01

    Full Text Available The study examines a Lower Jurassic (late Liassic cyclic lagoonal–peritidal stratigraphic unit outcropping in central western Crete (Tripolis unit, which corresponds to the eastern (internal part of the mainland Gavrovo-Tripolis platform, the most significant external platform of the Hellenides. The studied Tripolis carbonate sequence consists of meter-scale, shallowing-upward successions of restricted inner-carbonate platform facies, including cyclically repeated subtidal, intertidal and supratidal facies, that are separated by erosion surfaces (elementary cycles. Each cycle starts with relatively open-marine facies, which are overlain by shallower, more restricted facies (tidal flat progradation. The lithofacies association includes dolomitic intraclastic–peloidal–bioclastic wackestones–packstones/floatstones and grainstones/rudstones dominated by a restricted shallow-marine fauna (bivalves, gastropods, ostracods and seldom benthic foraminifers, representing a shallow subtidal to intertidal, moderately high-energy environment within an inner-platform setting (peritidal environment to restricted lagoon. This lithofacies association has been intermittently subaerially exposed and has undergone diagenetic processes in an inter- or supratidal environment, exhibiting features of vadose diagenesis and pedogenesis due to long-lasting exposure along certain horizons. The peritidal facies are capped by dolocretes controlled by root-activities (laminar dolocretes, peloidal–pisoid dolocretes and massive dolocretes, marking the end of each depositional cycle, and, thus, distinguishing the successive episodes of a prolonged subaerial exposure period and birth of paleosol horizons. Dolocretes consist a diagenetic facies, characterized by several vadose and pedogenic fabrics, including fenestral cavities with geopetal structures, “flower spar” to blocky sparry cement in primary pores, micritic coatings, crudely pelleted walls, alveolar

  16. Ground-based PTR-MS measurements of reactive organic compounds during the MINOS campaign in Crete, July–August 2001

    Directory of Open Access Journals (Sweden)

    G. Salisbury

    2003-01-01

    Full Text Available This study presents measurements of acetonitrile, benzene, toluene, methanol and acetone made using the proton-transfer-reaction mass spectrometry (PTR-MS technique at the Finokalia ground station in Crete during the Mediterranean INtensive Oxidant Study (MINOS in July-August 2001. Three periods during the campaign with broadly consistent back trajectories are examined in detail. In the first, air was advected from Eastern Europe without significant biomass burning influence (mean acetonitrile mixing ratio 154 pmol/mol. In the second period, the sampled air masses originated in Western Europe, and were advected approximately east-south-east, before turning south-west over the Black Sea and north-western Turkey. The third well-defined period included air masses advected from Eastern Europe passing east and south of/over the Sea of Azov, and showed significant influence by biomass burning (mean acetonitrile mixing ratio 436 pmol/mol, confirmed by satellite pictures. The mean toluene:benzene ratios observed in the three campaign periods described were 0.35, 0.37 and 0.22, respectively; the use of this quantity to determine air mass age is discussed. Methanol and acetone were generally well-correlated both with each other and with carbon monoxide throughout the campaign. Comparison of the acetone and methanol measurements with the MATCH-MPIC model showed that the model underestimated both species by a factor of 4, on average. The correlations between acetone, methanol and CO implied that the relatively high levels of methanol observed during MINOS were largely due to direct biogenic emissions, and also that biogenic sources of acetone were highly significant during MINOS (~35%. This in turn suggests that the model deficit in both species may be due, at least in part, to missing biogenic emissions.

  17. A Fiducial Reference Stie for Satellite Altimetry in Crete, Greece

    Science.gov (United States)

    Mertikas, Stelios; Donlon, Craig; Mavrocordatos, Constantin; Bojkov, Bojan; Femenias, Pierre; Parrinello, Tommaso; Picot, Nicolas; Desjonqueres, Jean-Damien; Andersen, Ole Baltazar

    2016-08-01

    With the advent of diverse satellite altimeters and variant measuring techniques, it has become mature in the scientific community, that an absolute reference Cal/Val site is regularly maintained to define, monitor, control the responses of any altimetric system.This work sets the ground for the establishment of a Fiducial Reference Site for ESA satellite altimetry in Gavdos and West Crete, Greece. It will consistently and reliably determine (a) absolute altimeter biases and their drifts; (b) relative bias among diverse missions; but also (c) continuously and independently connect different missions, on a common and reliable reference and also to SI-traceable measurements. Results from this fiducial reference site will be based on historic Cal/Val site measurement records, and will be the yardstick for building up capacity for monitoring climate change. This will be achieved by defining and assessing any satellite altimeter measurements to known, controlled and absolute reference signals with different techniques, processes and instrumentation.

  18. Smoking cessation delivery by general practitioners in Crete, Greece.

    Science.gov (United States)

    Girvalaki, Charis; Papadakis, Sophia; Vardavas, Constantine; Petridou, Eleni; Pipe, Andrew; Lionis, Christos

    2018-06-01

    Tobacco dependence treatment in clinical settings is of prime public health importance, especially in Greece, a country experiencing one of the highest rates of tobacco use in Europe. Our study aimed to examine the characteristics of tobacco users and document rates of tobacco treatment delivery in general practice settings in Crete, Greece. A cross-sectional sample of patients (n = 2, 261) was screened for current tobacco use in 25 general practices in Crete, Greece in 2015/16. Current tobacco users completed a survey following their clinic appointment that collected information on patient characteristics and rates at which the primary care physician delivered tobacco treatment using the evidence-based 4 A's (Ask, Advise, Assist, Arrange) model during their medical appointment and over the previous 12-month period. Multi-level modeling was used to analyze data and examine predictors of 4 A's delivery. Tobacco use prevalence was 38% among all patients screened. A total of 840 tobacco users completed the study survey [mean age 48.0 (SD 14.5) years, 57.6% male]. Approximately, half of the tobacco users reported their general practitioner 'asked' about their tobacco use and 'advised' them to quit smoking. Receiving 'assistance' with quitting (15.7%) and 'arranging' follow-up support (<3%) was infrequent. Patient education, presence of smoking-related illness, a positive screen for anxiety or depression and the type of medical appointment were associated with 4 A's delivery. Given the fundamental importance of addressing tobacco treatment, increasing the rates of 4 A's treatment in primary care settings in Greece is an important target for improving patient care.

  19. Objects and identities : Dowry and material culture in Venetian Crete in regional and European context (1600-1645)

    NARCIS (Netherlands)

    Markaki, T.

    2018-01-01

    This comparative study explores the socioeconomic and cultural meanings of the dowry movables in Venetian Crete and attempts to place the island in the broader context of European material culture studies; especially of those which are based on probate inventory research. Through qualitative and

  20. Collective Memory and Blood Feud: The Case of Mountainous Crete

    Directory of Open Access Journals (Sweden)

    Aris Tsantiropoulos

    2008-04-01

    Full Text Available Drawing upon ethnographic data from mountainous central Crete, a feuding society up to the present moment, this article will focus on cases of retaliatory crimes where men avenge a relative who was killed before they were born. In these cases, what is interesting is that there do not seem to be any factors in the present to fuel the fire of a past animosity between the two kinship groups. Instead, these men seek revenge looking either for the murderer himself or for one of his male relatives in the places where they were forced to emigrate after the commitment of crime in order to avoid the perpetuation of violent actions. Reflecting upon crime in a feuding society as a ‘cultural trauma’ for the identity of the victim’s kinship group, and elaborating upon the ideas that Freud has exposed in his article ‘Mourning and Melancholia’, the ways by which a memory of a past crime triggers another crime are explored here.

  1. Climatological aspects of cyclonic tracks associated with flood events in Crete, Greece

    Science.gov (United States)

    Flocas, H. A.; Tsanis, I. K.; Katavoutas, G.; Kouroutzoglou, J.; Iordanidou, V.; Alexakis, D. D.

    2017-11-01

    In this study, an attempt was made to identify the tracks of the synoptic-scale cyclones associated with flood events in Crete, a Greek island in the southern Aegean Sea and to investigate their kinematic and dynamic characteristics and vertical structure for a period of 25 years. Furthermore, a comparison is made with the corresponding characteristics of the population of surface cyclones passing over Crete during the same period. The Melbourne University Cyclone Tracking Algorithm was employed to examine the genesis and movement of these cyclones while their vertical profile was examined with the aid of the vertical tracing software, Vertical Tracking Scheme (VTS). The input data are based on ERA INTERIM reanalysis datasets with resolution 0.5° × 0.5° during the period 1990 to 2014. It was found that the vast majority originate mainly over the north African coasts, contrasting the preference of all cyclones passing over Crete to develop within the Southeast Mediterranean. Cyclones associated with the flood events are more intense than the cyclonic population, being mainly characterized by long duration and track length. Furthermore, they reveal characteristics of vertically organized baroclinic systems, suggesting that they are mainly driven by baroclinic processes at upper and lower levels.

  2. Middle Miocene E-W tectonic horst structure of Crete through extensional detachment faults

    International Nuclear Information System (INIS)

    Papanikolaou, D; Vassilakis, E

    2008-01-01

    Two east-west trending extensional detachment faults have been recognized in Crete, one with top-to-the-north motion of the hanging wall toward the Cretan Sea and one with top-to-the-south motion of the hanging wall toward the Libyan Sea. The east-west trending zone between these two detachment faults, which forms their common footwall, comprises a tectonic horst formed during Middle Miocene slip on the detachment faults. The detachment faults disrupt the overall tectono-stratigraphic succession of Crete and are localized along pre-existing thrust faults and along particular portions of the stratigraphic sequence, including the transition between the Permo-Triassic Tyros Beds and the base of the Upper Triassic-Eocene carbonate platform of the Tripolis nappe. By recognizing several different tectono-stratigraphic formations within what is generally termed the 'phyllite-quartzite', it is possible to distinguish these extensional detachment faults from thrust faults and minor discontinuities in the sequence. The deformation history of units within Crete can be summarized as: (i) compressional deformation producing arc-parallel east-west trending south-directed thrust faults in Oligocene to Early Miocene time (ii) extensional deformation along arc-parallel, east-west trending detachment faults in Middle Miocene time, with hanging wall motion to the north and south; (iii) Late Miocene-Quaternary extensional deformation along high-angle normal and oblique normal faults that disrupt the older arc-parallel structures

  3. Attenuation of S-waves in the lithosphere of the Sea of Crete according to OBS observations

    Science.gov (United States)

    Kovachev, S. A.; Kuzin, I. P.; Shoda, O. Yu.; Soloviev, S. L.

    1991-11-01

    Five OBS were installed in the Sea of Crete in 1987. During a period of nine days 430 local earthquakes were recorded. Hypocentres were determined for 85 microearthquakes. A correlation between magnitude ML and duration of seismic events on the records of the ocean bottom seismographs (OBS) was found from data of 14 shocks recorded simultaneously by OBS and some land-based Greek stations. A magnitude-frequency relationship for earthquakes recorded by OBS was obtained in the magnitude range ML = 2-4. Amplitude curves describing the attenuation of body waves in the lithosphere of the Sea of Crete were compiled. Assessment of quality factor Qs was made by comparison of empirical and theoretical amplitude curves. The values of Qs for the lithosphere of the Sea of Crete were calculated and found equal to 200-300. Low values of Qs and consequently strong attenuation of S-waves in the lithosphere of the Sea of Crete could be explained by extension of the lithosphere accompanied by its partial contamination with melted magma.

  4. Geostatistical Study of Precipitation on the Island of Crete

    Science.gov (United States)

    Agou, Vasiliki D.; Varouchakis, Emmanouil A.; Hristopulos, Dionissios T.

    2015-04-01

    precipitation which are fitted locally to a three-parameter probability distribution, based on which a normalized index is derived. We use the Spartan variogram function to model space-time correlations, because it is more flexible than classical models [3]. The performance of the variogram model is tested by means of leave-one-out cross validation. The variogram model is then used in connection with ordinary kriging to generate precipitation maps for the entire island. In the future, we will explore the joint spatiotemporal evolution of precipitation patterns on Crete. References [1] P. Goovaerts. Geostatistical approaches for incorporating elevation into the spatial interpolation of precipitation. Journal of Hydrology, 228(1):113-129, 2000. [2] N. B. Guttman. Accepting the standardized precipitation index: a calculation algorithm. American Water Resource Association, 35(2):311-322, 1999. [3] D. T Hristopulos. Spartan Gibbs random field models for geostatistical applications. SIAM Journal on Scientific Computing, 24(6):2125-2162, 2003. [4] A.G. Koutroulis, A.-E.K. Vrohidou, and I.K. Tsanis. Spatiotemporal characteristics of meteorological drought for the island of Crete. Journal of Hydrometeorology, 12(2):206-226, 2011. [5] T. B. McKee, N. J. Doesken, and J. Kleist. The relationship of drought frequency and duration to time scales. In Proceedings of the 8th Conference on Applied Climatology, page 179-184, Anaheim, California, 1993.

  5. Epidemiology of Dermatophytoses in Crete, Greece.

    Science.gov (United States)

    Maraki, Sofia; Mavromanolaki, Viktoria Eirini

    2016-01-01

    Dermatophytoses are among the most frequently diagnosed skin infections worldwide. However, the distribution of pathogenic species and the predominating anatomical sites of infection vary with geographical location and change over time. The aim of this study was to determine the epidemiological and aetiological factors of dermatophytoses in Crete, Greece over the last 5-year period (2011-2015) and their incidence in relation to the gender and the age of the patients. We compared our findings with those previously reported from the same area and from other parts of the world. A total of 2,910 clinical specimens (skin scrapings, nail clippings, and hair specimens) obtained from 2,751 patients with signs of dermatomycoses were examined using direct microscopy and culture. Overall, 294 specimens (10.1%) were proved mycologically positive for dermatophytes. The age of the patients ranged from 2 to 86 years (mean age, 37 years). Tinea corporis was the predominant clinical type of infection, followed by tinea unguium, tinea pedis, tinea capitis, tinea faciei, tinea cruris and tinea manuum. Among dermatophytes, eight species were isolated: Microsporum canis (35.8%), Trichophyton rubrum (35.1%), Trichophyton mentagrophytes (23.3%), Epidermophyton floccosum (2.5%), Microsporum gypseum (1.8%), Trichophyton violaceum (0.7%), Trichophyton verrucosum (0.4%), and Trichophyton tonsurans (0.4%). In our area, the most common dermatophyte was M. canis followed by T. rubrum. Increased migration, mass tourism, and climate changes will contribute to further changes in the epidemiology of dermatophytoses in our area. Continuing studies are necessary for determining the new epidemiological trends and to implement the appropriate control measures.

  6. Citrus Tristeza Virus on the Island of Crete

    DEFF Research Database (Denmark)

    Shegani, M.; Tsikou, D.; Velimirovic, A.

    2012-01-01

    Over a period of two years, more than 5,000 citrus trees were tested for the presence of Citrus tristeza virus (CTV) on the island of Crete, resulting in thirty eight positives. Comparisons of the relative transcript levels of CTV p23, coat protein (CP), polymerase (POL) and an intergenic (POL/p3...

  7. Exposure to methyl bromide during greenhouse fumigation on Crete, Greece

    NARCIS (Netherlands)

    Vreede, J.A.F. de; Boeft, J. den; Hemmen, J.J. van

    1998-01-01

    In agricultural areas where greenhouses and dwellings are intermixed, the general population as well as the professional applicators may be exposed to pesticides. In a field study on Crete, exposure to methyl bromide during soil fumigation was assessed. Exposure of applicators (both contractors and

  8. The Holy Name of Jesus in Venetian-Ruled Crete

    OpenAIRE

    Bacci, Michele

    2017-01-01

    Focusing on Andreas Ritzos' icon with the monogram IHS in Athens, this article offers insights about the role played by the monogram on Crete and points out that the particular solution shown in Ritzos' image is not in keeping with St. Bernardine's "icon" of the Holy Name of Jesus and indicates an association with the symbolism of the holy host.

  9. Modelling tectonic features of the Kissamos and Paleohora areas, Western Crete (Greece): combining geological and geophysical surveys

    Energy Technology Data Exchange (ETDEWEB)

    Moisidi, M; Vallianatos, F; Soupios, P [Laboratory of Geophysics and Seismology, Department of Natural Resources and Environment, Technological Educational Institute of Crete, 3 Romanou Str., Halepa, Chania, Crete 73133 (Greece); Kershaw, S [Institute for the Environment, Brunel University, Uxbridge, Middlesex, UB8 3PH (United Kingdom); Rust, D [Earth and Environmental Sciences, University of Portsmouth, Burnary Road, Portsmouth, PO1 3QL,UK (United Kingdom); Piscitelli, S [Istituto di Metodologie per I' Analisi Ambientale IMAA-CNR, C/da S Loja, 85050, Tito Scalo (PZ) (Italy)

    2013-04-15

    The purpose of this survey is the fault zone determination in Kissamos (NW Crete) and Paleohora (SW Crete) basins. The study area is located within the central forearc of the Hellenic subduction zone. 2D electrical resistivity tomography (ERT) has been applied to reveal fault zones. Ground-truthed fault evidence in the coast northwest of Kastelli-Kissamou and northeast of Paleohora is incorporated into the ERT data. Thirteen ERT profiles were obtained at several sites. Seven of the eight ERT profiles intersect fault zones in Kissamos. Five ERT profiles were conducted in Paleohora and three significant faults were identified. The results indicated the continuation of previously mapped faults as well as revealing unreported faults. The coastline of Paleohora and Grammeno can be associated with a system of fault zone striking almost E-W. We propose that the ERT method is a reliable and economic method at identifying buried fault zones in populated areas. Considering the proximity of the revealed fault zones in densely populated areas and the high seismic activity of the region the determination of the identified fault zones could contribute in earthquake hazard assessment studies for future seismic mitigation and urban planning strategies in the two areas for western Crete. (paper)

  10. Dynamics-based centrality for directed networks.

    Science.gov (United States)

    Masuda, Naoki; Kori, Hiroshi

    2010-11-01

    Determining the relative importance of nodes in directed networks is important in, for example, ranking websites, publications, and sports teams, and for understanding signal flows in systems biology. A prevailing centrality measure in this respect is the PageRank. In this work, we focus on another class of centrality derived from the Laplacian of the network. We extend the Laplacian-based centrality, which has mainly been applied to strongly connected networks, to the case of general directed networks such that we can quantitatively compare arbitrary nodes. Toward this end, we adopt the idea used in the PageRank to introduce global connectivity between all the pairs of nodes with a certain strength. Numerical simulations are carried out on some networks. We also offer interpretations of the Laplacian-based centrality for general directed networks in terms of various dynamical and structural properties of networks. Importantly, the Laplacian-based centrality defined as the stationary density of the continuous-time random walk with random jumps is shown to be equivalent to the absorption probability of the random walk with sinks at each node but without random jumps. Similarly, the proposed centrality represents the importance of nodes in dynamics on the original network supplied with sinks but not with random jumps.

  11. THESEUS: the first-scale 50 MEw THErmal Solar EUropean power station for the Island of Crete, Greece

    Energy Technology Data Exchange (ETDEWEB)

    Aringhof, Rainer [Pilkington Solar International (United States)

    1996-03-01

    The first solar power plant to receive funding from the European Union is to be constructed on the Island of Crete, Greece. This utility-scale 50 MWe plant is based on technology known as THERMIE (THErmal Solar European power station) and it represents a major breakthrough for Europe`s small solar thermal power community. The proposed THESEUS project uses an advanced parabolic trough collector field as the primary heat source and will be constructed between 1977 and 1999. (UK)

  12. Sustainable power planning for the island of Crete

    International Nuclear Information System (INIS)

    Giatrakos, Georgios P.; Tsoutsos, Theocharis D.; Zografakis, Nikos

    2009-01-01

    Crete, as one of the largest and most touristic islands of the Mediterranean, is facing abrupt population and economic growth tendencies that result in the incessant problem of inability to meet power demand increase. This paper evaluates the island's present electrical energy status, and examines the possibility of further penetration of sustainable energy. Various energy modelling software solutions are examined and evaluated, in order to form scenarios according to the governmental and EU directives for renewable energy sources (RES), as well as to the planned conventional power plant upgrades and LNG transition. RES are fully exploited in the plan's scenarios, always taking into account all technical and legislative limitations. Analysis shows that even the most modest and realistic RES implementation scenarios, combined with a partially successful demand restriction, could indeed contract the island's environmental footprint. RES penetration in Crete's electric seems to be able to surpass 30% by 2020, surpassing even the optimistic EU targets for 20% RES by 2020

  13. The THESEUS project -- 50 MWe solar thermal power for Crete

    Energy Technology Data Exchange (ETDEWEB)

    Schillig, F.; Geyer, M.; Kistner, R.; Aringhoff, R.; Nava, P.; Brakmann, G.

    1998-07-01

    A consortium of European industry, utilities and research institutions from Greece, Germany, Spain and Italy attempts to implement a 52 MWe solar thermal power plant with parabolic trough technology on the Greek island of Crete sponsored by the EU' s THERMIE program. The increased demand for electricity on the island, a consequence of the growing allurement of the island as a tourist resort, makes it necessary to expand the installed capacity on Crete during the next years. According to the capacity expansion plans of Greek' s utility PPC a 160 MWe heavy fuel-fired power plant complex--two 30 MWe diesel units and two 50 MWe steam turbine units--is foreseen to be built by the year 2002. In this paper a description of the technical, economical and environmental aspects of the THESEUS project is provided. Moreover a market entry strategy for solar thermal power generation is discussed.

  14. Stratigraphy of Neogene deposits in the Khania province, Crete, with special reference to foraminifera of the family Planorbulinidae and the genus Heterostegina

    NARCIS (Netherlands)

    Freudenthal, T.

    1969-01-01

    In this paper the stratigraphy of the Neogene deposits in the Khania Province, Crete, Greece, is described. Special attention is paid to the evolution and taxonomy of foraminiferal genera assigned previously to the family Planorbulinidae. This partial revision of the Planorbulinidae is based not

  15. Measuring the burden of herpes zoster and post herpetic neuralgia within primary care in rural Crete, Greece

    Directory of Open Access Journals (Sweden)

    Lionis Christos D

    2011-12-01

    Full Text Available Abstract Background Research has indicated that general practitioners (GPs have good clinical judgment in regards to diagnosing and managing herpes zoster (HZ within clinical practice in a country with limited resources for primary care and general practice. The objective of the current study was to assess the burden of HZ and post herpetic neuralgia (PHN within rural general practices in Crete, Greece. Methods The current study took place within a rural setting in Crete, Greece during the period of November 2007 to November 2009 within the catchment area in which the Cretan Rural Practice-based Research Network is operating. In total 19 GP's from 14 health care units in rural Crete were invited to participate, covering a total turnover patient population of approximately 25, 000 subjects. For the purpose of this study an electronic record database was constructed and used as the main tool for monitoring HZ and PHN incidence. Stress related data was also collected with the use of the Short Anxiety Screening Test (SAST. Results The crude incidence rate of HZ was 1.4/1000 patients/year throughout the entire network of health centers and satellite practices, while among satellite practices alone it was calculated at 1.3/1000 patients/year. Additionally, the standardised incidence density within satellite practices was calculated at 1.6/1000 patients/year. In regards to the stress associated with HZ and PHN, the latter were found to have lower levels of anxiety, as assessed through the SAST score (17.4 ± 3.9 vs. 21.1 ± 5.7; p = 0.029. Conclusions The implementation of an electronic surveillance system was feasible so as to measure the burden of HZ and PHN within the rural general practice setting in Crete.

  16. Clinical undergraduate training and assessment in primary health care: Experiences gained from Crete, Greece

    Directory of Open Access Journals (Sweden)

    Fioretos Michael

    2005-05-01

    Full Text Available Abstract Background Primary Health Care (PHC is increasingly being introduced into undergraduate medical education. In Greece, the Faculty of Medicine of the University of Crete was the first to introduce a 4-week long training in primary health care. This paper presents the experiences gained from the initial implementation of the teaching of practice-based primary care in rural Crete and reports on the assessment scale that was developed. Methods 284 students' case write-ups from the 6 primary care units (PCUs where they were allocated for the period 1990 to 1994 were analysed. The demographic data of the students and patients and the number of home visits were studied. Content analysis of the students' write-ups was carried out, using an assessment scale consisting of 10 dichotomous variables, in order to quantify eight (8 primary qualitative criteria. Results Internal reliability was estimated by the index KR20 = 0.67. Face and content validity was found to conform to the standards set for the course, while logistic linear regression analysis showed that the quality criteria could be used as an assessment scale. The number of home visits carried out varied between the various different PCUs (p Conclusion The primary health care course achieved the objectives of introducing students to comprehensive, community oriented care, although there was variation between the PCUs. The assessment scale that was developed to analyse the case-write ups of the students provided data that can be used to evaluate the course.

  17. Extension for Organic Agriculture: A Comparative Study between Baden-Württemberg, Germany and Crete, Greece

    Science.gov (United States)

    Österle, Nina; Koutsouris, Alex; Livieratos, Yannis; Kabourakis, Emmanuil

    2016-01-01

    Purpose: The aim of this paper is to compare the extension services offered in the field of organic agriculture (OA) in Baden-Württemberg (BW), Germany and Crete, Greece. Design/methodology approach: 16 in-depth interviews, 10 in BW and 6 in Crete, were carried out with representatives of OA extension providers; interviews were qualitatively…

  18. Optimal locations of establishing smoking cessation services for cancer patients in Crete, Greece

    Directory of Open Access Journals (Sweden)

    Dimitra Sifaki-Pistolla

    2017-05-01

    The proposed optimum locations for establishing smoking cessation services are expected to contribute to the enhancement of cancer control in Crete. Furthermore, this study will guide a smoking cessation program in the region of Crete aiming to minimize the burden of tobacco-induced cancers.

  19. Imaging of the central skull base.

    Science.gov (United States)

    Borges, Alexandra

    2009-11-01

    The central skull base (CSB) constitutes a frontier between the extracranial head and neck and the middle cranial fossa. The anatomy of this region is complex, containing most of the bony foramina and canals of the skull base traversed by several neurovascular structures that can act as routes of spread for pathologic processes. Lesions affecting the CSB can be intrinsic to its bony-cartilaginous components; can arise from above, within the intracranial compartment; or can arise from below, within the extracranial head and neck. Crosssectional imaging is indispensable in the diagnosis, treatment planning, and follow-up of patients with CSB lesions. This review focuses on a systematic approach to this region based on an anatomic division that takes into account the major tissue constituents of the CSB.

  20. Public and Private Cults of Hygieia (Particularly Focusing on Crete

    Directory of Open Access Journals (Sweden)

    Giampiera Arrigoni

    2012-07-01

    Full Text Available Aim of this article is a survey of the cults dedicated to Hygieia in public and private spheres. This is the occasion of analyzing the conception of health and Hygieia among the archaic poets, and the process by which Hygieia from personification became a deity. Also analyzed is the link of Hygieia with other deities or personifications, the symbolism of certain attributes and epithets in poetry and cult and the meaning of certain gestures. Particular attention is paid to Crete (especially Gortyna and finally to the presence of Hygieia in baths and thermae.

  1. On the wind power rejection in the islands of Crete and Rhodes

    International Nuclear Information System (INIS)

    Katsaprakakis, Dimitris Al.; Papadakis, Nikos; Christakis, Dimitris G.; Zervos, Arthouros

    2007-01-01

    Crete and Rhodes represent the two biggest isolated power systems in Greece. The energy production in both islands is based on thermal power plants. The annual wind energy rejection percentage is calculated for Crete and Rhodes in this paper. The rejected wind energy is defined as the electric energy produced by the wind turbines and not absorbed by the utility network, mainly due to power production system's stability and dynamic security reasons. A parametric calculation of the annual wind energy rejection percentage, in terms of the installed wind power, the power demand and the maximum allowed wind power instant penetration percentage, is accomplished. The methodology takes into account (i) the wind power penetration probability, restricted by the thermal generators technical minima and the maximum allowed wind power instant penetration percentage over the instant power demand; and (ii) the wind power production probability, derived by the islands' wind potential. The present paper indicates that isolated power systems which are based on thermal power plants have a limited wind power installation capacity - in order to achieve and maintain an adequate level of system stability. For a maximum wind power instant penetration percentage of 30% of the power demand, in order to ensure an annual wind energy rejection percentage less than 10%, the total installed wind power should not exceed the 40% of the mean annual power demand. The results of this paper are applicable to medium and great size isolated power systems, with particular features: (i) the power production is based on thermal power plants; (ii) the power demand exhibits intensive seasonal variations and is uncorrelated to the wind data; (iii) the mean annual power demand is greater than 10MW; and (iv) a high wind potential, presenting mean annual wind velocity values greater than 7.5ms-1, is recorded. (Author)

  2. First endemic freshwater Gammarus from Crete and its evolutionary history-an integrative taxonomy approach.

    Science.gov (United States)

    Hupało, Kamil; Mamos, Tomasz; Wrzesińska, Weronika; Grabowski, Michał

    2018-01-01

    The Mediterranean islands are known as natural laboratories of evolution with a high level of endemic biodiversity. However, most biodiversity assessments have focused mainly on terrestrial and marine fauna, leaving the freshwater animals aside. Crete is one of the largest islands in the Mediterranean Basin, with a long history of isolation from the continental mainland. Gammarid amphipods are often dominant in macrozoobenthic communities in European inland waters. They are widely used in biomonitoring and exotoxicological studies. Herein, we describe Gammarus plaitisi sp. nov., endemic to Cretan streams, based on morphological characters and a set of molecular species delimitation methods using mitochondrial cytochrome oxidase subunit I and 16S rRNA genes as well as nuclear 28S rDNA, ITS1 and EF1-alpha genes. The divergence of the new species is strongly connected with the geological history of the island supporting its continental origin.

  3. Clostridium difficile in Crete, Greece: epidemiology, microbiology and clinical disease.

    Science.gov (United States)

    Samonis, G; Vardakas, K Z; Tansarli, G S; Dimopoulou, D; Papadimitriou, G; Kofteridis, D P; Maraki, S; Karanika, M; Falagas, M E

    2016-01-01

    We studied the epidemiology and microbiology of Clostridium difficile and the characteristics of patients with C. difficile infection (CDI) in Crete in three groups of hospitalized patients with diarrhoea: group 1 [positive culture and positive toxin by enzyme immunoassay (EIA)]; group 2 (positive culture, negative toxin); group 3 (negative culture, negative toxin). Patients in group 1 were designated as those with definitive CDI (20 patients for whom data was available) and matched with cases in group 2 (40 patients) and group 3 (40 patients). C. difficile grew from 6% (263/4379) of stool specimens; 14·4% of these had positive EIA, of which 3% were resistant to metronidazole. Three isolates had decreased vancomycin susceptibility. Patients in groups 1 and 2 received more antibiotics (P = 0·03) and had more infectious episodes (P = 0·03) than patients in group 3 prior to diarrhoea. Antibiotic administration for C. difficile did not differ between groups 1 and 2. Mortality was similar in all three groups (10%, 12·5% and 5%, P = 0·49). CDI frequency was low in the University Hospital of Crete and isolates were susceptible to metronidazole and vancomycin.

  4. Pigment and terracotta analyses of Hellenistic figurines in Crete

    International Nuclear Information System (INIS)

    Maravelaki-Kalaitzaki, P.; Kallithrakas-Kontos, N.

    2003-01-01

    The results of the analyses performed on blue, black, brown, orange, white and purple pigments decorating Hellenistic figurines, excavated in a rock-cut tomb in the archaeological zone of Chania, Crete, Greece, are presented. Different spectroscopic techniques, such as Fourier transform infrared spectroscopy and energy dispersive X-ray fluorescence identified the compounds present in the chromatic layers. X-ray diffraction analysis gave complementary information and further support to the spectral assignments. Optical microscopy revealed the nature and sequence of the pigmented layer on the terracotta. Several precious pigments, such as Egyptian blue for the bluish areas, Tyrian purple for the purple ones, and the rare huntite for the white-pigmented areas were identified among the studied pigmented areas. The pigment analysis provides information on the technical aspects related to terracotta manufacture and preservation, and promotes historical indications on cultural and commercial changes among the Mediterranean civilisations

  5. First results on video meteors from Crete, Greece

    Science.gov (United States)

    Maravelias, G.

    2012-01-01

    This work presents the first systematic video meteor observations from a, forthcoming permanent, station in Crete, Greece, operating as the first official node within the International Meteor Organization's Video Network. It consists of a Watec 902 H2 Ultimate camera equipped with a Panasonic WV-LA1208 (focal length 12mm, f/0.8) lens running MetRec. The system operated for 42 nights during 2011 (August 19-December 30, 2011) recording 1905 meteors. It is significantly more performant than a previous system used by the author during the Perseids 2010 (DMK camera 21AF04.AS by The Imaging Source, CCTV lens of focal length 2.8 mm, UFO Capture v2.22), which operated for 17 nights (August 4-22, 2010) recording 32 meteors. Differences - according to the author's experience - between the two softwares (MetRec, UFO Capture) are discussed along with a small guide to video meteor hardware.

  6. Solar Orientations of Bronze Age Shrines in Gournia, Crete

    Science.gov (United States)

    Henriksson, G.; Blomberg, M.

    2009-08-01

    The measurements of orientations at Gournia are part of the Uppsala University project to investigate the nature of Minoan astronomy. The town is typical of Minoan settlements and therefore was chosen for the selection of representative buildings from different kinds of Minoan sites. We use classical archaeoastronomical methods and our own computer programs for calculation of the positions of the sun, moon and stars in the Aegean Bronze Age. We discovered that Gournia is the fourth Minoan site with shrines that are oriented to sunrise at lunar month intervals with respect to the equinoxes. There is also a Mycenaean shrine in the town and we compared its orientation to Mycenaean buildings of the same type in Crete.

  7. Seasonal monitoring of soil erosion at regional scale: An application of the G2 model in Crete focusing on agricultural land uses

    Science.gov (United States)

    Panagos, Panagos; Christos, Karydas; Cristiano, Ballabio; Ioannis, Gitas

    2014-04-01

    A new soil erosion model, namely G2, was applied in the island of Crete with a focus on agricultural land uses, including potential grazing lands. The G2 model was developed within the Geoland2 project as an agro-environmental service in the framework of the Global Monitoring for Environment and Security (GMES, now Copernicus) initiative. The G2 model takes advantage of the empirical background of the Universal Soil Loss Equation (USLE) and the Gavrilovic model, together with readily available time series of vegetation layers and 10-min rainfall intensity data to produce monthly time-step erosion risk maps at 300 m cell size. The innovations of the G2 model include the implementation of land-use influence parameters based on empirical data and the introduction of a corrective term in the estimation of the topographic influence factor. The mean annual erosion rate in Crete was found to be 8.123 t ha-1. The season from October to January (the rainy season in Crete) was found to be the most critical, accounting for 80% of the annual erosion in the island. Seasonal erosion figures proved to be crucial for the identification of erosion hotspots and of risky land uses. In Crete, high annual erosion figures were detected in natural grasslands and shrublands (14.023 t ha-1), mainly due to the intensification of livestock grazing during the past decades. The G2 model allows for the integrated spatio-temporal monitoring of soil erosion per land-use type based on moderate data input requirements and existing datasets.

  8. Evaluation of tsunami risk in Heraklion city, Crete, Greece, by using GIS methods

    Science.gov (United States)

    Triantafyllou, Ioanna; Fokaefs, Anna; Novikova, Tatyana; Papadopoulos, Gerasimos A.; Vaitis, Michalis

    2016-04-01

    The Hellenic Arc is the most active seismotectonic structure in the Mediterranean region. The island of Crete occupies the central segment of the arc which is characterized by high seismic and tsunami activity. Several tsunamis generated by large earthquakes, volcanic eruptions and landslides were reported that hit the capital city of Heraklion in the historical past. We focus our tsunami risk study in the northern coastal area of Crete (ca. 6 km in length and 1 km in maximum width) which includes the western part of the city of Heraklion and a large part of the neighboring municipality of Gazi. The evaluation of tsunami risk included calculations and mapping with QGIS of (1) cost for repairing buildings after tsunami damage, (2) population exposed to tsunami attack, (3) optimum routes and times for evacuation. To calculate the cost for building reparation after a tsunami attack we have determined the tsunami inundation zone in the study area after numerical simulations for extreme tsunami scenarios. The geographical distribution of buildings per building block, obtained from the 2011 census data of the Hellenic Statistical Authority (EL.STAT) and satellite data, was mapped. By applying the SCHEMA Damage Tool we assessed the building vulnerability to tsunamis according to the types of buildings and their expected damage from the hydrodynamic impact. A set of official cost rates varying with the building types and the damage levels, following standards set by the state after the strong damaging earthquakes in Greece in 2014, was applied to calculate the cost of rebuilding or repairing buildings damaged by the tsunami. In the investigation of the population exposed to tsunami inundation we have used the interpolation method to smooth out the population geographical distribution per building block within the inundation zone. Then, the population distribution was correlated with tsunami hydrodynamic parameters in the inundation zone. The last approach of tsunami risk

  9. Evaluation of promising technologies for soil salinity amelioration in Timpaki (Crete): a participatory approach

    Science.gov (United States)

    Panagea, I. S.; Daliakopoulos, I. N.; Tsanis, I. K.; Schwilch, G.

    2016-02-01

    Soil salinity management can be complex, expensive, and time demanding, especially in arid and semi-arid regions. Besides taking no action, possible management strategies include amelioration and adaptation measures. Here we apply the World Overview of Conservation Approaches and Technologies (WOCAT) framework for the systematic analysis and evaluation and selection of soil salinisation amelioration technologies in close collaboration with stakeholders. The participatory approach is applied in the RECARE (Preventing and Remediating degradation of soils in Europe through Land Care) project case study of Timpaki, a semi-arid region in south-central Crete (Greece) where the main land use is horticulture in greenhouses irrigated by groundwater. Excessive groundwater abstractions have resulted in a drop of the groundwater level in the coastal part of the aquifer, thus leading to seawater intrusion and in turn to soil salinisation. The documented technologies are evaluated for their impacts on ecosystem services, cost, and input requirements using a participatory approach and field evaluations. Results show that technologies which promote maintaining existing crop types while enhancing productivity and decreasing soil salinity are preferred by the stakeholders. The evaluation concludes that rainwater harvesting is the optimal solution for direct soil salinity mitigation, as it addresses a wider range of ecosystem and human well-being benefits. Nevertheless, this merit is offset by poor financial motivation making agronomic measures more attractive to users.

  10. The impact of changing climate conditions on the hydrological behavior of several Mediterranean sub-catchments in Crete

    Science.gov (United States)

    Eirini Vozinaki, Anthi; Tapoglou, Evdokia; Tsanis, Ioannis

    2017-04-01

    Climate change, although is already happening, consists of a big threat capable of causing lots of inconveniences in future societies and their economies. In this work, the climate change impact on the hydrological behavior of several Mediterranean sub-catchments, in Crete, is presented. The sensitivity of these hydrological systems to several climate change scenarios is also provided. The HBV hydrological model has been used, calibrated and validated for the study sub-catchments against measured weather and streamflow data and inputs. The impact of climate change on several hydro-meteorological parameters (i.e. precipitation, streamflow etc.) and hydrological signatures (i.e. spring flood peak, length and volume, base flow, flow duration curves, seasonality etc.) have been statistically elaborated and analyzed, defining areas of increased probability risk associated additionally to flooding or drought. The potential impacts of climate change on current and future water resources have been quantified by driving HBV model with current and future scenarios, respectively, for specific climate periods. This work aims to present an integrated methodology for the definition of future climate and hydrological risks and the prediction of future water resources behavior. Future water resources management could be rationally effectuated, in Mediterranean sub-catchments prone to drought or flooding, using the proposed methodology. The research reported in this paper was fully supported by the Project "Innovative solutions to climate change adaptation and governance in the water management of the Region of Crete - AQUAMAN" funded within the framework of the EEA Financial Mechanism 2009-2014.

  11. EIGENVECTOR-BASED CENTRALITY MEASURES FOR TEMPORAL NETWORKS*

    Science.gov (United States)

    TAYLOR, DANE; MYERS, SEAN A.; CLAUSET, AARON; PORTER, MASON A.; MUCHA, PETER J.

    2017-01-01

    Numerous centrality measures have been developed to quantify the importances of nodes in time-independent networks, and many of them can be expressed as the leading eigenvector of some matrix. With the increasing availability of network data that changes in time, it is important to extend such eigenvector-based centrality measures to time-dependent networks. In this paper, we introduce a principled generalization of network centrality measures that is valid for any eigenvector-based centrality. We consider a temporal network with N nodes as a sequence of T layers that describe the network during different time windows, and we couple centrality matrices for the layers into a supra-centrality matrix of size NT × NT whose dominant eigenvector gives the centrality of each node i at each time t. We refer to this eigenvector and its components as a joint centrality, as it reflects the importances of both the node i and the time layer t. We also introduce the concepts of marginal and conditional centralities, which facilitate the study of centrality trajectories over time. We find that the strength of coupling between layers is important for determining multiscale properties of centrality, such as localization phenomena and the time scale of centrality changes. In the strong-coupling regime, we derive expressions for time-averaged centralities, which are given by the zeroth-order terms of a singular perturbation expansion. We also study first-order terms to obtain first-order-mover scores, which concisely describe the magnitude of nodes’ centrality changes over time. As examples, we apply our method to three empirical temporal networks: the United States Ph.D. exchange in mathematics, costarring relationships among top-billed actors during the Golden Age of Hollywood, and citations of decisions from the United States Supreme Court. PMID:29046619

  12. Evaluation of wood residues from Crete as alternative fuels

    Energy Technology Data Exchange (ETDEWEB)

    Vamvuka, D. [Department of Mineral Resources Engineering, Technical University of Crete (Greece); Bandelis, G. [Professional School of Chania, EPAS Chania (Greece)

    2010-07-01

    Olive and citrus prunings, the main agricultural residues of Crete, are considered to be of premium importance for local energy production, substituting a large part of conventional fuels. The thermal behaviour of these fuels during combustion was studied by thermogravimetry, at non-isothermal heating conditions. Fly ashes were collected from tests in a lab-scale fluidized bed facility. The effect of the inorganic constituents of the fuels on slagging/fouling and agglomeration propensities, as well as environmental pollution was examined. Kinetic models were developed and reaction rates were determined. The agroresidues studied were characterized as good quality fuels, having high volatile and low ash and sulphur contents. Their ash was rich in Ca, Si, K and P minerals. However, fly ashes were poorer in alkali compounds, implying lower deposition and corrosion problems in boilers. The environmental impact of heavy metals is negligible. The thermochemical reactivity of the two fuels in air was very similar. A power low model fitted the experimental results accurately.

  13. Epidemiology of dermatophytoses in Crete, Greece between 2004 and 2010.

    Science.gov (United States)

    Maraki, S

    2012-06-01

    The present work was undertaken in order to study the epidemiology of dermatophytoses in the island of Crete, Greece, over a 7-year period (2004-2010) and to compare the results with those reported earlier from this region and from other parts of the world. A total of 3236 clinical specimens obtained from 2674 patients with signs of dermatomycoses were examined by direct micropscopy and culture. Overall, 392 specimens (12.1%) were proved mycologically positive for dermatophytes. The age of the patients ranged from 2 to 90 years (mean age, 41 years). Onychomycosis was the predominant clinical type of infection, followed by tinea pedis, tinea corporis, tinea capitis, tinea faciei, tinea manuum and tinea cruris. Among dermatophytes, nine species were isolated: Trichophyton rubrum (51%), Microsporum canis (18.9%), Trichophyton mentagrophytes var. interdigitale (18.4%), Trichophyton mentagrophytes var. mentagrophytes (5.1%), Epidermophyton floccosum (3.6%), Microsporum gypseum (1.5%), Trichophyton violaceum (0.8%), Trichophyton verrucosum (0.5%) and Trichophyton tonsurans (0.2%). In our area, the most common dermatophyte was T. rubrum followed by M. canis. Epidemiological studies regarding the current prevalence of dermatophytes in a certain region are needed for the appropriate management of these infections and implementation of effective prevention and control measures.

  14. Central Tracking Detector Based on Scintillating Fibres

    CERN Multimedia

    2002-01-01

    Scintillating fibres form a reasonable compromise for central tracking detectors in terms of price, resolution, response time, occupancy and heat production. \\\\ \\\\ New fluorescents with large Stokes shifts have been produced, capable of working without wavelength shifters. Coherent multibundles have been developed to achieve high packing fractions. Small segments of tracker shell have been assembled and beam tests have confirmed expectations on spatial resolution. An opto-electronic delay line has been designed to delay the track patterns and enable coincidences with a first level trigger. Replacement of the conventional phosphor screen anode with a Si pixel chip is achieved. This tube is called ISPA-tube and has already been operated in beam tests with a scintillating fibres tracker. \\\\ \\\\ The aim of the proposal is to improve hit densities for small diameter fibres by increasing the fraction of trapped light, by reducing absorption and reflection losses, by reflecting light at the free fibre end, and by inc...

  15. Tsunami Evacuation Exercises: the Case of Heraklion, Crete Isl., Greece

    Science.gov (United States)

    Triantafyllou, I.; Charalampakis, M.; Bocchini, G. M.; Novikova, T.; Papadopoulos, G. A.

    2016-12-01

    Effective tsunami evacuation requires appropriate awareness as regards good shelters selection. Field exercises may improve public awareness. A field exercise was organized in Heraklion, Crete Isl., in 2016. The area is part of the Hellenic Arc which is the most active structure in the Mediterranean. Large earthquakes triggered tsunamis that hit Heraklion in the past, such in AD 1303. After selecting various fault models, simulation of the 1303 tsunami showed important inundation zone in Heraklion. For the exercise needs a team of 30 volunteers was divided in 3 groups of 10 people each. Everyone was equipped with a mobile phone and a GPS device. The 3 groups were gathered in 3 coastal spots Heraklion situated 400 m apart each other. The scenario was that immediately after receiving in their mobile a tsunami warning message they will set on their personal GPS device and start evacuating inland on the best way they believed to do so. In each group, only 5 out of 10 volunteers were notified beforehand that the Eleftherias Square, located inland at distance satisfying evacuation needs in case of repeat of the 1303 tsunami, would be a good shelter to go. Using the Road Graph Plugin of QGIS, we calculated the shortest path distances which found equal to 800, 700 and 680 m. Adopting average velocity of 3 km/h we found that these distances can be covered within 18, 16 and 15 min, respectively. The routes towards the settlement spots as well as the times needed to arrive there by each one of the 30 volunteers were recorded by their personal GPS devices. The processing of the GPS tracks and their comparison with the theoretical routes and times showed good evacuation performance which is encouraging for the next phases of the Heraklion tsunami hazard mitigation program. This is contribution to the EU-FP7 projects ZIP (Zooming In between Plates, grant no: 604713, 2013) and ASTARTE (Assessment, Strategy And Risk Reduction for Tsunamis in Europe), grant no: 603839, 2013.

  16. Assessing tsunami vulnerability, an example from Herakleio, Crete

    Science.gov (United States)

    Papathoma, M.; Dominey-Howes, D.; Zong, Y.; Smith, D.

    Recent tsunami have caused massive loss of life, destruction of coastal infrastructures and disruption to economic activity. To date, tsunami hazard studies have concentrated on determining the frequency and magnitude of events and in the production of simplistic flood maps. In general, such maps appear to have assumed a uniform vulnerability of population, infrastructure and business. In reality however, a complex set of factors interact to produce a pattern of vulnerability that varies spatially and temporally. A new vulnerability assessment approach is described, that incorporates multiple factors (e.g. parameters relating to the natural and built environments and socio-demographics) that contribute to tsunami vulnerability. The new methodology is applied on a coastal segment in Greece and, in particular, in Crete, westof the city of Herakleio. The results are presented within a Geographic Information System (GIS). The application of GIS ensures the approach is novel for tsunami studies, since it permits interrogation of the primary database by several different end-users. For example, the GIS may be used: (1) to determine immediate post-tsunami disaster response needs by the emergency services; (2) to preplan tsunami mitigation measures by disaster planners; (3) as a tool for local planning by the municipal authorities or; (4) as a basis for catastrophe modelling by insurance companies. We show that population density varies markedly with the time of the year and that 30% of buildings within the inundation zone are only single story thus increasing the vulnerability of their occupants. Within the high inundation depth zone, 11% of buildings are identified as in need of reinforcement and this figure rises to 50% within the medium inundation depth zone. 10% of businesses are located within the high inundation depth zone and these may need to consider their level of insurance cover to protect against primary building damage, contents loss and business interruption

  17. Medicine and art: facial palsy depicted in archaic Greek art on Crete.

    Science.gov (United States)

    Pirsig, W; Helidonis, E; Velegrakis, G

    1995-01-01

    A small earthenware statuette was evacuated from the votive-depot of acropolis of Gortys, an ancient town in South-Crete/Greece. This ex-voto is dated approximately 7th to 6th century BC and very probably represents some symptoms of a stroke, especially the left facial palsy and the contracture of the left arm. Since the Minoan time until today, people of Crete have been offering ex-votos to gods or saints to ask for help in specific diseases.

  18. Miocene bristlemouths (Teleostei: Stomiiformes: Gonostomatidae) from the Makrilia Formation, Ierapetra, Crete

    Czech Academy of Sciences Publication Activity Database

    Přikryl, Tomáš; Carnevale, G.

    2017-01-01

    Roč. 16, č. 3 (2017), s. 266-277 ISSN 1631-0683 Institutional support: RVO:67985831 Keywords : Teleostei * Gonostomatidae * Crete * Neogene * Tortonian * Cyclothone gaudanti sp. nov. Subject RIV: DB - Geology ; Mineralogy OBOR OECD: Paleontology Impact factor: 1.376, year: 2016

  19. A comparison of acute hemorrhagic stroke outcomes in 2 populations: the Crete-Boston study.

    Science.gov (United States)

    Zaganas, Ioannis; Halpin, Amy P; Oleinik, Alexandra; Alegakis, Athanasios; Kotzamani, Dimitra; Zafiris, Spiros; Chlapoutaki, Chryssanthi; Tsimoulis, Dimitris; Giannakoudakis, Emmanouil; Chochlidakis, Nikolaos; Ntailiani, Aikaterini; Valatsou, Christina; Papadaki, Efrosini; Vakis, Antonios; Furie, Karen L; Greenberg, Steven M; Plaitakis, Andreas

    2011-12-01

    Although corticosteroid use in acute hemorrhagic stroke is not widely adopted, management with intravenous dexamethasone has been standard of care at the University Hospital of Heraklion, Crete with observed outcomes superior to those reported in the literature. To explore this further, we conducted a retrospective, multivariable-adjusted 2-center study. We studied 391 acute hemorrhagic stroke cases admitted to the University Hospital of Heraklion, Crete between January 1997 and July 2010 and compared them with 510 acute hemorrhagic stroke cases admitted to Massachusetts General Hospital, Boston, from January 2003 to September 2009. Of the Cretan cases, 340 received a tapering scheme of intravenous dexamethasone, starting with 16 to 32 mg/day, whereas the Boston patients were managed without steroids. The 2 cohorts had comparable demographics and stroke severity on admission, although anticoagulation was more frequent in Boston. The in-hospital mortality was significantly lower on Crete (23.8%, n=340) than in Boston (38.0%, n=510; Pmortality (Crete: 25.4%, n=307; Boston: 39.4%, n=510; Pmortality: Crete 20.8%; n=259; Boston 37.0%; n=359; Phemorrhages. After adjusting for acute hemorrhagic stroke volume/location, Glasgow Coma Scale, hypertension, diabetes mellitus, smoking, coronary artery disease and statin, antiplatelet, and anticoagulant use, intravenous dexamethasone treatment was associated with better functional outcomes and significantly lower risk of death at 30 days (OR, 0.357; 95% CI, 0.174-0.732). This study suggests that intravenous dexamethasone improves outcome in acute hemorrhagic stroke and supports a randomized clinical trial using this approach.

  20. Footwall degradation styles and associated sedimentary facies distribution in SE Crete: Insights into tilt-block extensional basins on continental margins

    Science.gov (United States)

    Alves, Tiago M.; Cupkovic, Tomas

    2018-05-01

    Depositional facies resulting from footwall degradation in extensional basins of SE Crete are studied based on detailed geological maps, regional transects, lithological columns and outcrop photos. During an extensional episode affecting Crete in the late Miocene-early Pliocene, depocentres trending N20°E and N70°E were filled with fan deltas, submarine mass-wasting deposits, sandy turbidites and fine-grained hemipelagites sourced from both nearby and distal sediment sources. Deposition of proximal continental and shallow-marine units, and relatively deep (marine) turbidites and mass-transport deposits, occurred within a complex mosaic of tectonically controlled depocentres. The new geological maps and transects in this work reveal that depositional facies in SE Crete were controlled by: a) their relative proximity to active faults and uplifting footwall blocks, b) the relative position (depth and relative height above sea level) of hanging-wall basins, and c) the nature of the basement units eroded from adjacent footwall blocks. Distal sediment sources supplied background siliciclastic sediment ('hemipelagites'), which differ markedly from strata sourced from local footwalls. In parallel, mass-transport of sediment was ubiquitous on tectonically active slopes, and so was the presence of coarse-grained sediment with sizes varying from large blocks > 50 m-wide to heterolithic mass-transport deposits and silty-sandy turbidites. We expect similar tectono-sedimentary settings to have predominated in tectonically active Miocene basins of the eastern Mediterranean, in which hydrocarbon exploration is occurring at present, and on rifted continental margins across the world.

  1. DNA methylation-based classification of central nervous system tumours

    DEFF Research Database (Denmark)

    Capper, David; Jones, David T.W.; Sill, Martin

    2018-01-01

    Accurate pathological diagnosis is crucial for optimal management of patients with cancer. For the approximately 100 known tumour types of the central nervous system, standardization of the diagnostic process has been shown to be particularly challenging - with substantial inter-observer variabil......Accurate pathological diagnosis is crucial for optimal management of patients with cancer. For the approximately 100 known tumour types of the central nervous system, standardization of the diagnostic process has been shown to be particularly challenging - with substantial inter......-observer variability in the histopathological diagnosis of many tumour types. Here we present a comprehensive approach for the DNA methylation-based classification of central nervous system tumours across all entities and age groups, and demonstrate its application in a routine diagnostic setting. We show...

  2. The Cretan Mesolithic in context: new data from Livari Skiadi (SE Crete

    Directory of Open Access Journals (Sweden)

    Tristan Carter

    2016-12-01

    Full Text Available Investigations at Livari (south-eastern Crete produced a small Mesolithic chipped stone assemblage, whose techno-typological characteristics situate it within an ‘early Holocene Aegean island lithic tradition’ (9000–7000 cal BC. The material provides antecedent characteristics for the lithics of Crete’s founder Neolithic population at Knossos (c. 7000–6500/6400 cal BC. The idiosyncrasies of the Knossian material can be viewed as a hybrid lithic tradition that emerged from interaction between migrant Anatolian farmers and indigenous hunter-gatherers. Small quantities of Melian obsidian at Livari attest to early Holocene maritime insular networks, knowledge of which likely enabled the first farmers’ successful voyage to Crete.

  3. Performance analysis of a grid connected photovoltaic park on the island of Crete

    International Nuclear Information System (INIS)

    Kymakis, Emmanuel; Kalykakis, Sofoklis; Papazoglou, Thales M.

    2009-01-01

    The favorable climate conditions of the island of Crete and the recent legislation for utilization of renewable energy sources provide a substantial incentive for installation of photovoltaic power plants. In this paper, the grid connected photovoltaic park of C. Rokas SA in Sitia, Crete, is presented, and its performance is evaluated. The photovoltaic park has a peak power of 171.36 kW p and has been in operation since 2002. The park is suitably monitored during 1 year, and the performance ratio and the various power losses (temperature, soiling, internal, network, power electronics, grid availability and interconnection) are calculated. The PV park supplied 229 MW h to the grid during 2007, ranging from 335.48 to 869.68 kW h. The final yield (Y F ) ranged from 1.96 to 5.07 h/d, and the performance ratio (PR) ranged from 58 to 73%, giving an annual PR of 67.36%

  4. Introducing seasonal hydro-meteorological forecasts in local water management. First reflections from the Messara site, Crete, Greece.

    Science.gov (United States)

    Koutroulis, Aristeidis; Grillakis, Manolis; Tsanis, Ioannis

    2017-04-01

    Seasonal prediction is recently at the center of the forecasting research efforts, especially for regions that are projected to be severely affected by global warming. The value of skillful seasonal forecasts can be considerable for many sectors and especially for the agricultural in which water users and managers can benefit to better anticipate against drought conditions. Here we present the first reflections from the user/stakeholder interactions and the design of a tailored drought decision support system in an attempt to bring seasonal predictions into local practice for the Messara valley located in the central-south area of Crete, Greece. Findings from interactions with the users and stakeholders reveal that although long range and seasonal predictions are not used, there is a strong interest for this type of information. The increase in the skill of short range weather predictions is also of great interest. The drought monitoring and prediction tool under development that support local water and agricultural management will include (a) sources of skillful short to medium term forecast information, (b) tailored drought monitoring and forecasting indices for the local groundwater aquifer and rain-fed agriculture, and (c) seasonal inflow forecasts for the local dam through hydrologic simulation to support management of freshwater resources and drought impacts on irrigated agriculture.

  5. Legal history of the revolt of Saint Titus in Fourteenth century Venetian Crete (1363-1366

    Directory of Open Access Journals (Sweden)

    Matteo Magnani

    2013-04-01

    Full Text Available The article examines all the different judicial aspects of the response which was given by the Republic of Venice to the serious revolution exploded in Crete in 1363. From the legal point of view, this response was structured on the procedures of exception (inquisitio ex officio, arbitrium, privilege and grace normally applied in late Middle Ages as effective means to preserve political authority. These procedures were used by Venice as flexible elements to create consent and to legitimate its power.

  6. A study of correlation between seismicity and mental health: Crete, 2008–2010

    Directory of Open Access Journals (Sweden)

    G.C. Anagnostopoulos

    2015-01-01

    Full Text Available We compared the number of M > 2 earthquakes in an area, including the island of Crete, Greece, to the number of admissions to the Psychiatric Inpatient Unit of the University of Crete (IPU/UoC, during the period 2008–2010. We found that when earthquakes with M 6.4 occurred in the region examined, the number of monthly admissions to the Acute Care Unit of the IPU/UoC, NAA, reached lowest values, whereas this number increased when the monthly number NE of small (M < 3 earthquakes increased. We also found a positive correlation between the total number of monthly admissions NA and NE (r = 0.601/P = 0.001. When a daily resolution analysis was performed for the month with the highest value of NE, we found that an abrupt increase in the number of small earthquakes was followed by an increase in the number of admissions after ∼2 days (during that month, from a total of 71 patients, 38/10 people were diagnosed with schizophrenia/bipolar disorder. We hypothesize that seismic activity might be a significant contributing factor influencing the frequency of admissions of psychotic disorders in Crete in the period 2008–2010 and that the beneficial/adverse effects are related to the anomalous electric field/extra low frequency–ultra low frequency emissions.

  7. Environmental impacts on human health during a Saharan dust episode at Crete Island, Greece

    Energy Technology Data Exchange (ETDEWEB)

    Nastos, P.T. [Univ. of Athens, Athen (Greece). Lab. of Climatology and Atmospheric Environment; Kampanis, N.A. [Foundation for Research and Technology, Hellas (Greece). Inst of Applied and Computational Mathematics; Giaouzaki, K.N. [Univ. of Crete, Iraklion (Greece). Dept. of Cardiology; Matzarakis, A. [Univ. of Freiburg (Germany). Meteorological Inst.

    2011-10-15

    The objective of this study is to examine the synergistic environmental impacts (thermal bioclimatic conditions and air quality due to particulate pollution) with cardiovascular and respiratory syndromes, in Heraklion in the northern part of Crete Island, during a Saharan dust episode on March 22-23, 2008. Daily counts of admissions for cardiovascular and respiratory syndromes were obtained from the two main hospitals in Heraklion. The corresponding daily meteorological parameters, such as maximum and minimum air temperature, relative humidity, wind speed and cloud cover, from the meteorological station of Heraklion (Hellenic National Meteorological Service), were processed in order to estimate and analyze the bioclimatic conditions expressed by the Physiologically Equivalent Temperature (PET), which is based on the energy balance models of the human body. Dust concentrations were derived from the SKIRON forecast model of the University of Athens, while Moderate Resolution Imaging Spectroradiometer (MODIS) products such as aerosol optical depth at 550 nm (AOD550), aerosol small mode fraction (SM), Aangstroem exponent in the 550-865 nm band and mass concentration, were used for the episode. Besides, daily composite anomalies (reference period: 1968-1996) of the air temperature and vector wind from the middle to the lower atmospheric levels (500 hPa - mean sea level) on March 23, 2008, were calculated from the reanalysis datasets of the National Centers for Environmental Prediction/National Center for Atmospheric Research (NCEP/NCAR). The analysis of MODIS and SKIRON products showed that high AOD{sub 550} values (>0.9) and high dust concentration (>250 {mu}g/m{sup 3}), respectively, appear on March 23, 2008, while the respiratory admissions were five-fold than the mean daily admissions on the same day of the emergence of the Saharan dust episode (key day). According to the analysis, this is due to the existence of coarse-mode particles along the dust pathway, which

  8. DNA methylation-based classification of central nervous system tumours.

    Science.gov (United States)

    Capper, David; Jones, David T W; Sill, Martin; Hovestadt, Volker; Schrimpf, Daniel; Sturm, Dominik; Koelsche, Christian; Sahm, Felix; Chavez, Lukas; Reuss, David E; Kratz, Annekathrin; Wefers, Annika K; Huang, Kristin; Pajtler, Kristian W; Schweizer, Leonille; Stichel, Damian; Olar, Adriana; Engel, Nils W; Lindenberg, Kerstin; Harter, Patrick N; Braczynski, Anne K; Plate, Karl H; Dohmen, Hildegard; Garvalov, Boyan K; Coras, Roland; Hölsken, Annett; Hewer, Ekkehard; Bewerunge-Hudler, Melanie; Schick, Matthias; Fischer, Roger; Beschorner, Rudi; Schittenhelm, Jens; Staszewski, Ori; Wani, Khalida; Varlet, Pascale; Pages, Melanie; Temming, Petra; Lohmann, Dietmar; Selt, Florian; Witt, Hendrik; Milde, Till; Witt, Olaf; Aronica, Eleonora; Giangaspero, Felice; Rushing, Elisabeth; Scheurlen, Wolfram; Geisenberger, Christoph; Rodriguez, Fausto J; Becker, Albert; Preusser, Matthias; Haberler, Christine; Bjerkvig, Rolf; Cryan, Jane; Farrell, Michael; Deckert, Martina; Hench, Jürgen; Frank, Stephan; Serrano, Jonathan; Kannan, Kasthuri; Tsirigos, Aristotelis; Brück, Wolfgang; Hofer, Silvia; Brehmer, Stefanie; Seiz-Rosenhagen, Marcel; Hänggi, Daniel; Hans, Volkmar; Rozsnoki, Stephanie; Hansford, Jordan R; Kohlhof, Patricia; Kristensen, Bjarne W; Lechner, Matt; Lopes, Beatriz; Mawrin, Christian; Ketter, Ralf; Kulozik, Andreas; Khatib, Ziad; Heppner, Frank; Koch, Arend; Jouvet, Anne; Keohane, Catherine; Mühleisen, Helmut; Mueller, Wolf; Pohl, Ute; Prinz, Marco; Benner, Axel; Zapatka, Marc; Gottardo, Nicholas G; Driever, Pablo Hernáiz; Kramm, Christof M; Müller, Hermann L; Rutkowski, Stefan; von Hoff, Katja; Frühwald, Michael C; Gnekow, Astrid; Fleischhack, Gudrun; Tippelt, Stephan; Calaminus, Gabriele; Monoranu, Camelia-Maria; Perry, Arie; Jones, Chris; Jacques, Thomas S; Radlwimmer, Bernhard; Gessi, Marco; Pietsch, Torsten; Schramm, Johannes; Schackert, Gabriele; Westphal, Manfred; Reifenberger, Guido; Wesseling, Pieter; Weller, Michael; Collins, Vincent Peter; Blümcke, Ingmar; Bendszus, Martin; Debus, Jürgen; Huang, Annie; Jabado, Nada; Northcott, Paul A; Paulus, Werner; Gajjar, Amar; Robinson, Giles W; Taylor, Michael D; Jaunmuktane, Zane; Ryzhova, Marina; Platten, Michael; Unterberg, Andreas; Wick, Wolfgang; Karajannis, Matthias A; Mittelbronn, Michel; Acker, Till; Hartmann, Christian; Aldape, Kenneth; Schüller, Ulrich; Buslei, Rolf; Lichter, Peter; Kool, Marcel; Herold-Mende, Christel; Ellison, David W; Hasselblatt, Martin; Snuderl, Matija; Brandner, Sebastian; Korshunov, Andrey; von Deimling, Andreas; Pfister, Stefan M

    2018-03-22

    Accurate pathological diagnosis is crucial for optimal management of patients with cancer. For the approximately 100 known tumour types of the central nervous system, standardization of the diagnostic process has been shown to be particularly challenging-with substantial inter-observer variability in the histopathological diagnosis of many tumour types. Here we present a comprehensive approach for the DNA methylation-based classification of central nervous system tumours across all entities and age groups, and demonstrate its application in a routine diagnostic setting. We show that the availability of this method may have a substantial impact on diagnostic precision compared to standard methods, resulting in a change of diagnosis in up to 12% of prospective cases. For broader accessibility, we have designed a free online classifier tool, the use of which does not require any additional onsite data processing. Our results provide a blueprint for the generation of machine-learning-based tumour classifiers across other cancer entities, with the potential to fundamentally transform tumour pathology.

  9. A Spatio-Temporal Algorithmic Procedure for Environmental Policymaking in the Municipality of Arkalochori in the Greek Island of Crete

    Science.gov (United States)

    Batzias, F. A.; Sidiras, D. K.; Giannopoulos, Ch.; Spetsidis, I.

    2009-08-01

    This work deals with a methodological framework designed/developed under the form of a spatio-temporal algorithmic procedure for environmental policymaking at local level. The procedure includes 25 activity stages and 9 decision nodes, putting emphasis on (i) mapping on GIS layers water supply/demand and modeling of aquatic pollution coming from point and non-point sources, (ii) environmental monitoring by periodically measuring the main pollutants in situ and in the laboratory, (iii) design of environmental projects, decomposition of them into sub-projects and combination of the latter to form attainable alternatives, (iv) multicriteria ranking of alternatives, according to a modified Delphi method, by using as criteria the expected environmental benefit, the attitude of inhabitants, the priority within the programme of regional development, the capital required for the investment and the operating cost, and (v) knowledge Base (KB) operation/enrichment, functioning in combination with a data mining mechanism to extract knowledge/information/data from external Bases. An implementation is presented referring to the Municipality of Arkalochori in the Greek island of Crete.

  10. Drought, flood and rainfall analysis under climate change in Crete, Greece

    Science.gov (United States)

    Tapoglou, Evdokia; Vozinaki, Anthi-Eirini; Tsanis, Ioannis; Nerantzaki, Sofia; Nikolaidis, Nikolaos

    2017-04-01

    In this study an analysis on the drought frequency and magnitude under climate change in Crete, Greece is performed. The analysis was performed for the time period from 1983-2100, divided into three sub-periods (1983-1999, 2000-2049 and 2050-2099) for inter-comparison. Two climate models were studied MPI-ESM-LR-r1-CSC-REMO and EC-EARTH-r12-SMHI-RCA4, following three possible representative concentration pathways (+2.6, +4.5 and +8.5 W/m2). In order to perform the analysis the results of a SWAT simulation which covered the entity of Crete using 352 subbasins, was used. Drought events are recognized by using the Standardized Precipitation Index (SPI) to identify the meteorological drought events and Standardized Runoff Index (SRI) for hydrological droughts. SPI and SRI drought indices, were used in order to identify the number of drought events for each climate model and scenario. In all cases, an increase in both severity and number of drought events was calculated for the future periods, compared to the baseline period 1983-1999. This increase was smaller for the +2.6 W/m2 scenario and largest for the +8.5 W/m2. The magnitude of events with 10 and 100 years return period was calculated for the subbasins of Crete and the most vulnerable were identified, both in terms of severity and the change throughout the years in index magnitude. Next a flood frequency analysis was performed for the entity of Crete Island in order to calculate the magnitude of events with 10 and 100 years return period. In order to perform the flood frequency analysis, the results of the SWAT simulation in terms of runoff in each subbasin are used. By calculating the magnitude of flood events with 10 and 100 years return period and the change in the magnitude throughout the time periods the most vulnerable subbasins are identified. The same frequency analysis was performed for the precipitation at each subbasin, and the magnitude of extreme precipitation events with 10 and 100 years return

  11. Deviance and Morals: a study of sixteenth-century Crete under Venetian rule: A first approach

    Directory of Open Access Journals (Sweden)

    Romina N. Tsakiri

    2007-11-01

    Full Text Available This article examines indicatively offences such as blasphemy, sodomy, adultery and bigamy and the penalties imposed by the Venetian authorities on the island of Crete in sixteenth century. As the sixteenth century was characterised by a strong tendency towards the moralisation of life in the states of Western Europe, State and Church focused on all forms of deviance from the Christian order: issues related to faith, individual behaviour, family life and sexuality, all became objects of discipline. The Venetian state, in collaboration with the church, also penalised offences related to Christian morality, in the island of Crete as well as elsewhere in the Venetian state. The attitude of the Venetian state towards Crete, differences between the city of Venice and the island in the administration of rules governing deviance and promoting moral standards were slight, despite the presence of a substantial Orthodox community. Although, in some offences related to family life Venetian law respected the customs of the Orthodox church. Furthermore, in some cases the treatment of Jews was stricter, as Jews were considered as a possible threat to Christianity and the social structure of the Venetian state. A more significant factor than religious difference on the treatment of these offences was class and economic status and gender. Finally, the moral discipline and strict control over aspects of community life was intended not only to promote the well-being of subjects, and therefore the administration of the state, but also the protection of the prestige, identity and financial interests of the ruling class of nobility.

  12. Sources of atmospheric aerosols controlling PM10 levels in Heraklion, Crete during winter time

    Science.gov (United States)

    Kalivitis, Nikolaos; Kouvarakis, Giorgos; Stavroulas, Iasonas; Kandilogiannaki, Maria; Vavadaki, Katerina; Mihalopoulos, Nikolaos

    2016-04-01

    High concentrations of Particulate Matter (PM) in the atmosphere have negative impact to human health. Thresholds for ambient concentrations that are defined by the directive 2008/50/EC are frequently exceeded even at background conditions in the Mediterranean region as shown in earlier studies. The sources of atmospheric particles in the urban environment of a medium size city of eastern Mediterranean are studied in the present work in order to better understand the causes and characteristics of exceedances of the daily mean PM10limit value of 50 μg m-3. Measurements were performed at the atmospheric quality measurement station of the Region of Crete, at the Heraklion city center on Crete island, during the winter/spring period of 2014-2015 and 2015-2016. Special emphasis was given to the study of the contribution of Black Carbon (BC) to the levels of PM10. Continuous measurements were performed using a beta-attenuation PM10monitor and a 7-wavelength Aethalometer with a time resolution of 30 and 5 minutes respectively. For direct comparison to background regional conditions, concurrent routine measurements at the atmospheric research station of University of Crete at Finokalia were used as background reference. Analysis of exceedances in the daily PM10 mass concentration showed that the total of the exceedances was related to long range transport of Saharan dust rather than local sources. However, compared to the Finokalia station it was found that there were 20% more exceedances in Heraklion, the addition of transported dust on the local pollution was the reason for the additional exceedance days. Excluding dust events, it was found that the PM10variability was dependent on the BC abundance, traffic during rush hours in the morning and biomass burning for domestic heating in the evening contributed significantly to PM10levels in Heraklion.

  13. Expansionary Adaptive Transformations of Socio-Hydrological Systems (SHSs): The Case of Drought in Messara Plain, Crete, Greece.

    Science.gov (United States)

    Sapountzaki, Kalliopi; Daskalakis, Ioannis

    2018-05-01

    The paper attempts to document the ontology of socio-hydrological systems (SHSs), propose approaches of delimitation of SHSs' (territorial) boundaries, and investigate operational aspects of their adaptation to drought including repercussions on sustainability. To this end, a series of hypotheses are tested: (a) SHSs contain social subsystems with different expectations regarding water resources, different adaptive capacities, adaptation limits and prospects of sustainability, (b) SHSs do not adapt homogenously; some of their subsystems manage optimum adaptation, others fail to adapt and (c) territorial transformation of SHSs (e.g., through expansion of SHSs) may be the result of differential adaptation and sustainability potential within the SHS owing to power relations. After testing above hypotheses in the SHS of Messara Plain, Crete, the authors found out that powerful and dynamic sub-SHSs expand or break the boundaries of the initial SHS by establishing new relationships with other SHSs for the sake of resilience resources. Conversely, powerless sub-SHSs incapable to adapt descend and disappear. Therefore, territorial transformation of SHSs comes about from a combination of successful and failed adaptations, or in other words from different adaptation limits within SHSs. Consequently, water management and local development planning to guarantee adaptability to drought for all should be based on SHSs' analysis and management, not on jurisdictional areas or hydrological basins.

  14. Suicide by pesticide poisoning: findings from the island of Crete, Greece.

    Science.gov (United States)

    Kastanaki, Anastasia E; Kraniotis, Christos F; Kranioti, Elena F; Nathena, Despoina; Theodorakis, Pavlos N; Michalodimitrakis, Manolis

    2010-01-01

    The role of pesticides in suicidal acts has not yet received adequate attention in Greece despite an evident rise of 39% in pesticide use over the period 1990-1992 to 2002-2004. To investigate the epidemiology of pesticide suicide on the Greek island of Crete, a largely rural agricultural area, and by further exploring the victim profiles, as well as patterns and trends of pesticide ingestion, to suggest probable preventive measures. Self-poisoning suicides between 1999 and 2007 were reviewed and information gathered was entered into a computerized database. The overall incidence of intentional pesticide poisoning was 1.7 per 100,000, representing the second most frequently used suicide method after hanging. The victim profile was composed of the following features: middle aged male, rural habitant, who carried out a suicidal act by consuming primarily methomyl or paraquat (WHO toxicity class Ib and class II, respectively). As to the place of death, the vast majority was found dead in the place of intoxication. Pesticide self-poisoning accounts for a quarter of the suicides in Crete. More detailed research is required to identify aspects of these deaths amenable to prevention, but measures such as bans on the most toxic pesticides and changes in storage practice would appear to be sensible initial approaches.

  15. Assessment of public acceptance and willingness to pay for renewable energy sources in Crete

    Energy Technology Data Exchange (ETDEWEB)

    Zografakis, Nikolaos [Regional Energy Agency of Crete, Region of Crete, 71202 Heraklion (Greece); Sifaki, Elli; Pagalou, Maria; Nikitaki, Georgia; Psarakis, Vasilios [Department of Economics, University of Crete, University Campus, 74100 Rethymnon (Greece); Tsagarakis, Konstantinos P. [Department of Environmental Engineering, Democritus University of Thrace, 67100 Xanthi (Greece)

    2010-04-15

    The aim of this study is to analyse and to evaluate the citizens' public acceptance and willingness to pay (WTP), for Renewable Energy Sources (RES) in Crete. For this purpose a contingent valuation study was conducted, using a double bound dichotomous choice format to elicit people's WTP and factors affecting it. Residents of 1440 households all over Crete were interviewed face-to-face. Major conclusions can be used as a basis for sustainable energy planning, for policies and the formulation of awareness campaigns and for RES investment programs and projects in order to prepare implementation conditions and enhance public acceptance of renewable energy investments and programmes. Mean WTP per household was found to be 16.33EUR to be paid quarterly as an additional charge on the electricity bill. Larger willingness to pay was reported by those with high family income and residence size, those having a higher level of energy information and awareness concerning climatic change, those who have invested in some energy saving measures, and those who suffer from more electricity shortages than others. (author)

  16. Trends in metabolic syndrome risk factors among adolescents in rural Crete between 1989 and 2011.

    Science.gov (United States)

    Girvalaki, Charis; Vardavas, Constantine; Papandreou, Christopher; Christaki, Georgia; Vergetaki, Anna; Tsiligianni, Ioanna G; Hatzis, Christos; Kafatos, Anthony

    2014-01-01

    To investigate all the important factors contributing to the development of metabolic syndrome (MetS) as well as to explore the changes of these factors, over time, by comparing adolescent populations of rural areas of Heraklion, Crete, for the years 2011 and 1989. This study was carried out within two rural areas of the Heraklion region in Crete, Greece. The 1989 study was conducted in the village of Agia Varvara and the respective 2011 study within the municipality of Minoa Pediados. The study population consisted of 150 high school students (97 girls and 69 boys) in 1989 and 66 (30 girls and 36 boys) elementary (6th grade) and high school students in 2011, aged from 12 to 14 years old. Anthropometric, blood pressure and biochemical information was obtained. Of the MetS risk factors studied, only obesity incidence was found higher in 2011 compared to 1989 (obese adolescents 1.3% in 1989 versus 21.2% in 2011, prise in obesity levels as well as to the decrease in hypertension, total cholesterol and LDL- cholesterol, as observed from the comparison of the years 1989 and 2011.

  17. An integrated multi-parameter monitoring approach for the quantification and mitigation of the climate change impact on the coasts of Eastern Crete, S. Aegean Sea (Project AKTAIA)

    Science.gov (United States)

    Ghionis, George; Alexandrakis, George; Karditsa, Aikaterini; Sifnioti, Dafni; Vousdoukas, Michalis; Andreadis, Olympos; Petrakis, Stelios; Poulos, Serafim; Velegrakis, Adonis; Kampanis, Nikolaos; Lipakis, Michalis

    2014-05-01

    The AKTAIA project aims at the production of new knowledge regarding the forms of manifestation of the climate change and its influence on the stability and evolution of the coastal landforms along the shoreline of eastern Crete (approximate length: 757 km), taking into account the various aspects of human intervention. Aerial photographs, satellite images and orthophotomaps have been used to produce a detailed coastline map and to study the morphological characteristics of the coastal zone of Eastern Crete. More than 100 beach zones have been visited during three field campaigns, which included geomorphological and human intervention mapping, topographic, meteorological and oceanographic measurements and sedimentological sampling and observations. In addition, two pilot sites (one in the north and one in the south part of Crete) are being monitored, via the installation of coastal video monitoring systems, shore-based meteorological stations and wave-tide recorders installed in the nearshore zone. Detailed seafloor mapping with the use of side scan sonar and scuba diving and bathymetric surveys were conducted in the two pilot sites. Meteorological and oceanographic data from all existing land-based meteorological stations, oceanographic buoys and the ERA-interim dataset are used to determine the wind and wave climate of each beach. The collected climatic, sedimentological and coastal environmental data are being integrated in a GIS database that will be used to forecast the climatic trends in the area of Crete for the next decades and to model the impact of the climatic change on the future evolution of the coastal zone. New methodologies for the continuous monitoring of land-sea interaction and for the quantification of the loss of sensitive coastal zones due to sea-level rise and a modified Coastal Vulnerability Index for a comparative evaluation of the vulnerability of the coasts are being developed. Numerical modelling of the nearshore hydrodynamics and the

  18. DIRC-based PID for the EIC central detector

    Energy Technology Data Exchange (ETDEWEB)

    Dzhygadlo, Roman; Schwarz, Carsten; Schwiening, Jochen [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Peters, Klaus [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, Darmstadt (Germany); Goethe-Universitaet Frankfurt (Germany); Collaboration: DIRC at EIC RD-Collaboration

    2015-07-01

    One of the key requirements for the central detector of a future Electron-Ion Collider (EIC) is to provide radially compact Particle Identification (PID) (e/π,π/K,K/p) over a wide momentum range. It is expected that the PID system will need to include one or more Cherenkov counters to achieve this goal. With a radial size of only a few cm, a DIRC counter (Detector of Internally Reflected Cherenkov light) is potentially an attractive option. The DIRC rate at EIC R and D Collaboration was formed by groups in the United States and Germany in 2011 with funding from DOE to investigate ways to extend the momentum coverage of DIRC counters for the EIC detector by up to 50% beyond the current state of the art. Possible design improvements include a complex focusing system, multi-anode sensors with smaller pixels, a time-based reconstruction algorithm, and chromatic dispersion mitigation. Both Geant and ray-tracing simulations are used to optimize the design configuration of the DIRC counter in terms of the performance and the best integration with the EIC detector. We discuss the current status of the design studies and the possible improvements to the Cherenkov angle resolution and the photon yield.

  19. The Development of Topography in Ancient and Active Orogens: Case Studies of Landscape Evolution in the Southern Appalachians, USA and Crete, Greece

    Science.gov (United States)

    Gallen, Sean Francis

    valley bottoms and mountain peaks > 160%. The most parsimonious driving mechanism to explain all evidence presented is uplift by dynamic topography. Chapter 2 confronts a long-standing debate over the style of orogenesis above the Hellenic subduction zone where two competing hypotheses are used to explain the rise of topography. Distinguishing between these hypotheses hinges on the kinematics of large faults associated with a series to topographic escarpments, known as the Hellenic troughs. Late Pleistocene marine terraces, optically stimulated luminescence geochronology, and structural mapping in South-central Crete and the Late Quaternary eustatic curve provide the dataset to test the kinematics of the Ptolemy fault, one of the Hellenic trough faults. Long term (104 -- 105 yr) rock uplift rates are synthesized and active faults identified. Fault-scaling properties demonstrate that active onshore extensional faulting is geometrically inconsistent with contractional shortening along the Ptolemy fault. This finding indicates that the Ptolemy, and probably all of the Hellenic trough faults, accommodates extension-to-transtension. The regional uplift of South-central Crete is interpreted as the result of underplating along the plate interface, as demonstrated by uplift of both the foot-and-hanging walls of active extensional faults with respect to sea level. The Hellenic troughs are grabens rising over an inflating subduction wedge. Chapter 3 exploits fortuitous geologic circumstances in South-central Crete to document the landscape response to changes in the rate of rock uplift and the impact that lithology has on geomorphic sensitivity to tectonic signals. Suites of topographic and drainage basin metrics responsive to rock uplift are used to evaluate how changing conditions are manifested in the landscape. Findings indicate that the landscape is insensitive to changes in rock uplift rate that initiated > 400 Ka, suggesting geomorphic response times here are long

  20. Fractal systems of central places based on intermittency of space-filling

    International Nuclear Information System (INIS)

    Chen Yanguang

    2011-01-01

    Highlights: → The idea of intermittency is introduced into central place model. → The revised central place model suggests incomplete space filling. → New central place fractals are presented for urban analysis. → The average nearest distance is proposed to estimate the fractal dimension. → The concept of distance-based space is replaced by that of dimension-based space. - Abstract: The central place models are fundamentally important in theoretical geography and city planning theory. The texture and structure of central place networks have been demonstrated to be self-similar in both theoretical and empirical studies. However, the underlying rationale of central place fractals in the real world has not yet been revealed so far. This paper is devoted to illustrating the mechanisms by which the fractal patterns can be generated from central place systems. The structural dimension of the traditional central place models is d = 2 indicating no intermittency in the spatial distribution of human settlements. This dimension value is inconsistent with empirical observations. Substituting the complete space filling with the incomplete space filling, we can obtain central place models with fractional dimension D < d = 2 indicative of spatial intermittency. Thus the conventional central place models are converted into fractal central place models. If we further integrate the chance factors into the improved central place fractals, the theory will be able to explain the real patterns of urban places very well. As empirical analyses, the US cities and towns are employed to verify the fractal-based models of central places.

  1. On the dynamics of synoptic scale cyclones associated with flood events in Crete

    Science.gov (United States)

    Flocas, Helena; Katavoutas, George; Tsanis, Ioannis; Iordanidou, Vasiliki

    2015-04-01

    Flood events in the Mediterranean are frequently linked to synoptic scale cyclones, although topographical or anthropogenic factors can play important role. The knowledge of the vertical profile and dynamics of these cyclones can serve as a reliable early flood warning system that can further help in hazard mitigation and risk management planning. Crete is the second largest island in the eastern Mediterranean region, being characterized by high precipitation amounts during winter, frequently causing flood events. The objective of this study is to examine the dynamic and thermodynamic mechanisms at the upper and lower levels responsible for the generation of these events, according to their origin domain. The flooding events were recorded for a period of almost 20 years. The surface cyclones are identified with the aid of MS scheme that was appropriately modified and extensively employed in the Mediterranean region in previous studies. Then, the software VTS, specially developed for the Mediterranean cyclones, was employed to investigate the vertical extension, slope and dynamic/kinematic characteristics of the surface cyclones. Composite maps of dynamic/thermodynamic parameters, such as potential vorticity, temperature advection, divergence, surface fluxes were then constructed before and during the time of the flood. The dataset includes 6-hourly surface and isobaric analyses on a 0.5° x 0.5° regular latitude-longitude grid, as derived from the ERA-INTERIM Reanalysis of the ECMWF. It was found that cyclones associated with flood events in Crete mainly generate over northern Africa or southern eastern Mediterranean region and experience their minimum pressure over Crete or southwestern Greece. About 84% of the cyclones extend up to 500hPa, demonstrating that they are well vertically well-organized systems. The vast majority (almost 84%) of the surface cyclones attains their minimum pressure when their 500 hpa counterparts are located in the NW or SW, confirming

  2. Integrated protecting plan for beach erosion. A case study in Plaka beach, E. Crete, Greece

    Science.gov (United States)

    Petrakis, Stelios; Alexandrakis, George; Kozyrakis, George; Hatziyanni, Eleni; Kampanis, Nikolaos

    2015-04-01

    Coastal zones are among the most active areas on Earth, being subjected to extreme wind / wave conditions, thus vulnerable to erosion. In Greece and Crete in particular, beach zones are extremely important for the welfare of the inhabitants, since, apart for the important biological and archaeological value of the beach zones, the socio-economic value is critical since a great number of human activities are concentrated in such areas (touristic facilities, fishing harbors etc.). The present study investigates the erosional procedures observed in Plaka beach, E. Crete, Greece, a highly touristic developed area with great archaeological interest and proposes a cost-effective solution. The factors taken into consideration for the proposed solution in reducing the erosion of the beach were the study of the climatological, geological and geomorphological regime of the area, the recent (~70 years) shifting of the coastline through the study of topographic maps, aerial photographs and satellite images, the creation of detailed bathymetric and seabed classification maps of the area and finally, a risk analysis in terms of erosional phenomena. On the basis of the above, it is concluded that the area under investigation is subjected to an erosional rate of about 1 m/10 years and the total land-loss for the past 70 years is about 4600 m2. Through the simulation of the wave regime we studied 3 possible scenarios, the "do-nothing" scenario, the construction of a detached submerged breakwater at the depth of 3 meters and, finally, the armoring of the existing beach-wall through the placement of appropriate size and material boulders, forming an artificial slope for the reducing of the wave breaking energy and a small scale nourishment plan. As a result, through the modeling of the above, the most appropriate and cost-effective solution was found to be the third, armoring of the existing coastal wall and nourishment of the beach periodically, thus the further undermining of the

  3. Bat species richness and activity over an elevation gradient in mediterranean shrublands of Crete

    Directory of Open Access Journals (Sweden)

    Panagiotis Georgiakakis

    2010-08-01

    Full Text Available Abstract
    The effect of elevation on bat species richness and activity was investigated in shrublands of central Crete (Greece using broad-band acoustic surveys. Recordings of echolocation calls were made in 15 transects equally distributed in three distinct elevation zones (500, 1000 and 1500 m a.s.l. during spring and autumn 2007-2008. Time-expanded calls were subsequently identified with the use of quadratic discriminant functions.
    Out of 13 species recorded, Hypsugo savii, Pipistrellus kuhlii and Tadarida teniotis were the most common and abundant. Many Rhinolophus hipposideros were also recorded in all elevation zones. Thirteen species were recorded in the lower elevation zone, 7 species in the mid one and 8 species in the 1500 m a.s.l. sites. Species richness, the number of bat passes of the most abundant species, as well as the total number of bat passes were not significantly affected by elevation. In spring both species richness and bat activity were higher than in autumn, although the corresponding difference in temperature was not significant.
    The high variability in both bat activity and the number of species found per transect in each elevation zone probably depended on the presence of other habitat types in the close vicinity, while roost availability and location might also have played an important role.
    We suggest that the ability of bats to perform regular movements along the elevational gradient has to be taken in account when assessing elevational patterns in bat diversity and activity. The geology of the study area is also of considerable importance through its effect on foraging and roosting opportunities for bats.

    Riassunto
    Ricchezza specifica e attività dei chirotteri lungo un gradiente altitudinale nella macchia mediterranea di Creta
    L’effetto della quota su ricchezza in specie e

  4. 3D reconstruction and digitalization of an archeological site, Itanos, Crete

    Directory of Open Access Journals (Sweden)

    Rudy Ercek

    2010-04-01

    Full Text Available The city of Itanos is situated in the North-East of Crete. Between 1994 and 2005, the French School of Archaeology at Athens (Efa and the Center for Mediterranean Studies in Rethymnon carried out excavation campaigns during which a necropolis and an Archaic building have been explored by a team of the CReA. A very close collaboration between archeologists, engineers and computer graphic designers allowed the 3D reconstruction of these remains. The archeologist was able to directly verify his hypotheses during the reconstruction process. In summer 2007 and 2008, a 3D digitalization of Itanos was made in order to insert the 3D reconstructions into the actual landscape.

  5. Report on the 11th European Fusion Physics Workshop (Heraklion, Crete, 8-10 December 2003)

    International Nuclear Information System (INIS)

    Campbell, D J; Becoulet, A; Counsell, G; Federici, G; Imbeaux, F; Kirschner, A; Krieger, K; Ortolani, S; Pitts, R; Philipps, V; Zastrow, K-D

    2005-01-01

    The 11th EFPW took place in December 2003 at Heraklion in Crete, hosted by the Association EURATOM-Greece and the FORTH Institute, Heraklion and sponsored by the European Commission. Within the overall theme of 'plasma-wall interactions (PWI) and their implications for impurity generation and transport', four topics of importance to the future development of magnetically confined fusion were discussed in detail. Key PWI issues for ITER were also reviewed, the programmes of the two European physics task forces, on PWI and on integrated tokamak modelling, were discussed, and several topical reviews on key physics R and D issues for ITER were presented. The main issues discussed and the areas identified as requiring further study are summarized here. (conference report)

  6. Development of highly workable concrete, 'Neuro-crete'. Part 1. ; Basic properties of Neuro-crete and application to large-scale structures with heavy-reinforcement. Koryudo concrete (Neuro crete) no kaihatsu. 1. ; Neuro crete no kiso bussei to kamitsu haikin wo yusuru doboku kozobutsu eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Miura, N; Chikamatsu, R; Sogo, S; Haga, T; Iriya, K; Taniguchi, M [Obayashi Corp., Tokyo (Japan)

    1993-08-10

    This paper introduces a highly workable concrete, 'Neuro-crete' developed for the purpose of simplifying construction of concrete structures and improving their guality. This concrete has a feature that it can reduce or eliminate a compacting process. Resistance to separation of coarse aggregate from mortar (separation resistance) is required. A difference of the material from conventional concrete is an increased unit particulate amount (binder + inert particulate). The binders may include cement, blast furnace slag particulate, flyash, silica fume, and expander. The inert particulate may be limestone powder. Kinds and mixing ratio of binders are important in improving fluidity. The separation resistivity is largely affected by a water-cement ratio and a water-binder ratio. A flow distance limit exists to maintain the fluidity without decreasing the compression strength after curing. The internal structure having become denser suppresses progress of neutralization or salt penetration. Drying contraction is equivalent to or less than the conventional concrete. 5 refs., 30 figs., 3 tabs.

  7. Centipede assemblages along an urbanization gradient in the city of Heraklion, Crete (Greece

    Directory of Open Access Journals (Sweden)

    Gabriella Papastefanou

    2015-06-01

    Full Text Available Global urbanization is a major force that causes alteration and loss of natural habitats. Urban ecosystems are strongly affected by humans and there is a gradient of decreasing human influence from city centers to natural habitats. To study ecological changes along this continuum, researchers introduced the urban-rural gradient approach. The responses of centipedes to an urbanization gradient (urban-suburban-rural areas were studied using pitfall traps in and near the city of Heraklion, in the island of Crete, Greece, from November 2010 to November 2011. Our results do not support the intermediate disturbance hypothesis, in which suburban areas located in the transitional zone between urban and rural habitats failed to indicate significant increase in terms of species richness and diversity.

  8. Reporting new cases of anaemia in primary care settings in Crete, Greece: a rural practice study

    Directory of Open Access Journals (Sweden)

    Lionis Christos

    2012-04-01

    Full Text Available Abstract Background Early diagnosis of anaemia represents an important task within primary care settings. This study reports on the frequency of new cases of anaemia among patients attending rural primary care settings in Crete (Greece and to offer an estimate of iron deficiency anaemia (IDA frequency in this study group. Methods All patients attending the rural primary health care units of twelve general practitioners (GPs on the island of Crete for ten consecutive working days were eligible to participate in this study. Hemoglobin (Hb levels were measured by portable analyzers. Laboratory tests to confirm new cases of anaemia were performed at the University General Hospital of Heraklion. Results One hundred and thirteen out of 541 recruited patients had a low value of Hb according to the initial measurement obtained by the use of the portable analyzer. Forty five (45.5% of the 99 subjects who underwent laboratory testing had confirmed anaemia. The mean value of the Hb levels in the group with confirmed anaemia, as detected by the portable analyzer was 11.1 g/dl (95% Confidence Interval (CI from 10.9 to 11.4 and the respective mean value of the Hb levels obtained from the full blood count was 11.4 g/dl (95% CI from 11.2 to 11.7 (P = 0.01. Sixteen out of those 45 patients with anaemia (35.6% had IDA, with ferritin levels lower than 30 ng/ml. Conclusion Keeping in mind that this paper does not deal with specificity or sensitivity figures, it is suggested that in rural and remote settings anaemia is still invisible and point of care testing may have a place to identify it.

  9. Distinct phases of eustatic and tectonic forcing for late Quaternary landscape evolution in southwest Crete, Greece

    Directory of Open Access Journals (Sweden)

    V. Mouslopoulou

    2017-09-01

    Full Text Available The extent to which climate, eustasy and tectonics interact to shape the late Quaternary landscape is poorly known. Alluvial fans often provide useful indexes that allow the decoding of information recorded on complex coastal landscapes, such as those of the eastern Mediterranean. In this paper we analyse and date (using infrared stimulated luminescence (IRSL dating a double alluvial fan system on southwest Crete, an island straddling the forearc of the Hellenic subduction margin, in order to constrain the timing and magnitude of its vertical deformation and discuss the factors contributing to its landscape evolution. The studied alluvial system is exceptional because each of its two juxtaposed fans records individual phases of alluvial and marine incision, thus providing unprecedented resolution in the formation and evolution of its landscape. Specifically, our analysis shows that the fan sequence at Domata developed during Marine Isotope Stage (MIS 3 due to five distinct stages of marine transgressions and regressions and associated river incision, in response to sea-level fluctuations and tectonic uplift at averaged rates of  ∼ 2.2 mm yr−1. Interestingly, comparison of our results with published tectonic uplift rates from western Crete shows that uplift during 20–50 kyr BP was minimal (or even negative. Thus, most of the uplift recorded at Domata must have occurred in the last 20 kyr. This implies that eustasy and tectonism impacted the landscape at Domata over mainly distinct time intervals (e.g. sequentially and not synchronously, with eustasy forming and tectonism preserving the coastal landforms.

  10. Absolute Sea Level Monitoring and Altimeter Calibration At Gavdos, Crete, Greece

    Science.gov (United States)

    Pavlis, E. C.; Gavdos Team

    We present the mean sea level (MSL) monitoring aspect of the altimeter calibration fa- cility under deployment on western Crete and the isle of Gavdos. The Eastern Mediter- ranean area is one of great interest for its intense tectonic activity as well as for its regional oceanography. Recent observations have convincingly demonstrated the im- portance of that area for the regional meteorological and climatological changes. Tide- gauge monitoring with GPS has gained importance lately since tectonics contaminate the inferred sea level variations, and a global network of tide-gauges with long his- torical records can be used as satellite altimeter calibration sites for current and fu- ture missions (e.g. TOPEX/POSEIDON, GFO, JASON-1, ENVISAT, etc.). This is at present a common IOC-GLOSS-IGS effort, already underway (TIGA). Crete hosts two of the oldest tide-gauges in the regional network and our project will further ex- pand it to the south of the island with a new site on the isle of Gavdos, the southernmost European parcel of land. One component of our "GAVDOS" project is the repeated occupation of two already in existence tide-gauge sites at Souda Bay and Heraklion, and their tie to the new facility. We show here initial results from positioning of these sites and some of the available tidal records. Gavdos is situated under a ground-track crossing point of the present T/P and JASON-1 orbits. It is an ideal calibration site if the tectonic motions are monitored precisely and continuously. Our plans include the deployment of additional instrumentation at this site: GPS and DORIS beacons for positioning, transponders for direct calibration, water vapor radiometers, GPS-loaded buoys, airborne surveys with gravimeters and laser profiling lidars, etc., to ensure the best possible and most reliable results.

  11. Impact of the financial crisis on adherence to treatment of a rural population in Crete, Greece.

    Science.gov (United States)

    Tsiligianni, Ioanna G; Papadokostakis, Polyvios; Prokopiadou, Dimitra; Stefanaki, Ioanna; Tsakountakis, Nikolaos; Lionis, Christos

    2014-01-01

    The global economic crisis has affected Greece. Data on patients' adherence to medications for chronic diseases are missing. The objective of this study was to identify to what extent the financial crisis and the repeated pharmacists strike have influenced patients adherence to therapy. A quantitative and qualitative study in rural Crete was designed and implemented in February 2013 with the use of a pretested questionnaire with opened and closed questions. Setting Rural practices in a well-defined geographical area of Crete. The questionnaire was addressed in all patients that visited the rural practices with chronic or acute diseases for two consecutive weeks. Main Outcome(s) and Measure(s): Age, annual income, adherence to therapy, patient's views and feelings. 288 patients participated. The mean age was 68±6.87. The majority of the patients have lowered the doses of several medications by themselves as they weren't able to afford the cost ie; all patients receiving insulin had lowered the dosages; 46.42% of patients with COPD or asthma had stopped their medications completely, decreased dosages or used similar medications that had in the past; patients with dislipidemia received their medications as suggested only in 51.8%. Patients with cardiovascular diseases received their medications as suggested in 75.6% while the rest have dismissed or skipped dosages. Most common emotions reported were those of sadness, fear, stress, anxiety and isolation. The economic crisis has influenced patients' adherence to therapy in rural areas as well as their psychological and emotional status. There is an urgent need for action within the context of primary care.

  12. Identifying multiple influential spreaders based on generalized closeness centrality

    Science.gov (United States)

    Liu, Huan-Li; Ma, Chuang; Xiang, Bing-Bing; Tang, Ming; Zhang, Hai-Feng

    2018-02-01

    To maximize the spreading influence of multiple spreaders in complex networks, one important fact cannot be ignored: the multiple spreaders should be dispersively distributed in networks, which can effectively reduce the redundance of information spreading. For this purpose, we define a generalized closeness centrality (GCC) index by generalizing the closeness centrality index to a set of nodes. The problem converts to how to identify multiple spreaders such that an objective function has the minimal value. By comparing with the K-means clustering algorithm, we find that the optimization problem is very similar to the problem of minimizing the objective function in the K-means method. Therefore, how to find multiple nodes with the highest GCC value can be approximately solved by the K-means method. Two typical transmission dynamics-epidemic spreading process and rumor spreading process are implemented in real networks to verify the good performance of our proposed method.

  13. Central Sensitization-Based Classification for Temporomandibular Disorders: A Pathogenetic Hypothesis

    Directory of Open Access Journals (Sweden)

    Annalisa Monaco

    2017-01-01

    Full Text Available Dysregulation of Autonomic Nervous System (ANS and central pain pathways in temporomandibular disorders (TMD is a growing evidence. Authors include some forms of TMD among central sensitization syndromes (CSS, a group of pathologies characterized by central morphofunctional alterations. Central Sensitization Inventory (CSI is useful for clinical diagnosis. Clinical examination and CSI cannot identify the central site(s affected in these diseases. Ultralow frequency transcutaneous electrical nerve stimulation (ULFTENS is extensively used in TMD and in dental clinical practice, because of its effects on descending pain modulation pathways. The Diagnostic Criteria for TMD (DC/TMD are the most accurate tool for diagnosis and classification of TMD. However, it includes CSI to investigate central aspects of TMD. Preliminary data on sensory ULFTENS show it is a reliable tool for the study of central and autonomic pathways in TMD. An alternative classification based on the presence of Central Sensitization and on individual response to sensory ULFTENS is proposed. TMD may be classified into 4 groups: (a TMD with Central Sensitization ULFTENS Responders; (b TMD with Central Sensitization ULFTENS Nonresponders; (c TMD without Central Sensitization ULFTENS Responders; (d TMD without Central Sensitization ULFTENS Nonresponders. This pathogenic classification of TMD may help to differentiate therapy and aetiology.

  14. A telehealth integrated asthma-COPD service for primary care: a proposal for a pilot feasibility study in Crete, Greece

    Directory of Open Access Journals (Sweden)

    Tzanakis Nikolaos E

    2010-07-01

    Full Text Available Abstract Background Chronic obstructive pulmonary disease (COPD and asthma are considered underdiagnosed and misdiagnosed chronic diseases. In The Netherlands, a COPD-asthma telemedicine service has been developed to increase GPs' ability to diagnose and manage COPD and asthma. A telemedicine COPD-asthma service may benefit Greece as it is a country, partly due to its geography, that does not have easy access to pulmonologists. Findings Therefore, a pilot feasibility study has been designed in Greece in order to establish this telemedicine service. Ten rural practices, in the island of Crete, with an average population of 2000 patients per practice will pilot the project supported by three pulmonologists. This paper presents the translated interfaces, the flowcharts and the steps that are considered as necessary for this feasibility study in Crete, Greece.

  15. 2D and 3D imaging of the metamorphic carbonates at Omalos plateau/polje, Crete, Greece by employing independent and joint inversion on resistivity and seismic data

    Directory of Open Access Journals (Sweden)

    Pangratis Pangratis

    2012-07-01

    Full Text Available A geophysical survey carried out at Omalos plateau in Chania, Western Crete, Greece employed seismic as well as electrical tomography methods in order to image karstic structures and the metamorphic carbonates (Tripali unit and Plattenkalk group which are covered by post-Mesozoic deposits (terra rossa, clays, sands and gravels. The geoelectrical sections image the metamorphic carbonates which exhibit a highly irregular relief. At the central part of the plateau the thickness of post-Mesozoic deposits (terra rossa, clays, sands and gravels ranges from 40-130 m. A 3D resistivity image was generated by inverting resistivity data collected on a grid to the south west at the Omalos plateau. The 3D resistivity image delineated a karstic structure at a depth of 25 to 55 m. On the same grid the depth to the top of the karstified carbonates ranges from 25-70 m. This is also verified on the resistivity sections and seismic velocity sections along lines 5 and 7 of the above mentioned grid which are derived from the cross-gradients joint inversion.

  16. Municipal solid waste composition determination supporting the integrated solid waste management system in the island of Crete

    International Nuclear Information System (INIS)

    Gidarakos, E.; Havas, G.; Ntzamilis, P.

    2006-01-01

    A one-year survey was conducted in the greater region of Crete (located at the lower region of the Aegean Sea) for the purpose of identifying waste composition (including chemical and physical characterization), as well as any seasonal variation. The investigation was carried out repeatedly at seven landfills and one transfer station in Crete, in four phases. Each sampling phase corresponded to a season (autumn, winter, spring, summer). ASTM D5231-92(2003) standard method and RCRA Waste Sampling Draft Technical Guidance were used. Hand sorting was used for classifying the collected wastes into the following categories: plastics, paper, metals, aluminium, leather-wood-textiles-rubbers, organic wastes, non-combustibles and miscellaneous. Further analysis included proximate and ultimate analysis of combustible materials. Metals such as lead, cadmium and mercury were also investigated. The results show that there has been a significant decrease of organic wastes during the last decade due to the increase of packaging materials, as a result of a change in consumption patterns. Three main waste categories were determined: organic wastes, paper and plastics, which combined represent 76% of the total waste in Crete. Furthermore, a high fraction of glass and a seasonal variation of aluminium indicate a strong correlation of waste composition with certain human activities, such as tourism. There is also a variation between the municipal solid waste (MSW) composition in the region of Crete (2003-2004) and MSW composition suggested in the National Solid Waste Planning (2000) [National Solid Waste Planning, 2000. Completion and particularization of Common Ministerial Act 113944//1944/1997: National Solid Waste Planning, June 2000]. The results of this survey are to be utilized by the regional solid waste authorities in order to establish an integrated waste treatment site, capable of fulfilling the regional waste management demands

  17. Municipal solid waste composition determination supporting the integrated solid waste management system in the island of Crete.

    Science.gov (United States)

    Gidarakos, E; Havas, G; Ntzamilis, P

    2006-01-01

    A one-year survey was conducted in the greater region of Crete (located at the lower region of the Aegean Sea) for the purpose of identifying waste composition (including chemical and physical characterization), as well as any seasonal variation. The investigation was carried out repeatedly at seven landfills and one transfer station in Crete, in four phases. Each sampling phase corresponded to a season (autumn, winter, spring, summer). ASTM D5231-92(2003) standard method and RCRA Waste Sampling Draft Technical Guidance were used. Hand sorting was used for classifying the collected wastes into the following categories: plastics, paper, metals, aluminium, leather-wood-textiles-rubbers, organic wastes, non-combustibles and miscellaneous. Further analysis included proximate and ultimate analysis of combustible materials. Metals such as lead, cadmium and mercury were also investigated. The results show that there has been a significant decrease of organic wastes during the last decade due to the increase of packaging materials, as a result of a change in consumption patterns. Three main waste categories were determined: organic wastes, paper and plastics, which combined represent 76% of the total waste in Crete. Furthermore, a high fraction of glass and a seasonal variation of aluminium indicate a strong correlation of waste composition with certain human activities, such as tourism. There is also a variation between the municipal solid waste (MSW) composition in the region of Crete (2003-2004) and MSW composition suggested in the National Solid Waste Planning (2000) [National Solid Waste Planning, 2000. Completion and particularization of Common Ministerial Act 113944//1944/1997: National Solid Waste Planning, June 2000]. The results of this survey are to be utilized by the regional solid waste authorities in order to establish an integrated waste treatment site, capable of fulfilling the regional waste management demands.

  18. A Multidisciplinary Workshop: Self-Assembling Peptide Systems in Biology, Medicine and Engineering, Crete, Greece, July 1-6, 1999

    Science.gov (United States)

    1999-07-06

    Bombyx mori silk fibroin. Structures with polar ap -s h eets and -turns, stacking with the hydrophobic methyl groups of the alanine units in contact, are...and Science in Crete Preface The idea of organizing this workshop originated from a series of unexpected events. During a visit with Drs. Amalia...and Europe. Biology has asked some fundamental questions about nature and our own being, the origin of species, the development of living systems and

  19. Human management and landscape changes at Palaikastro (Eastern Crete) from the Late Neolithic to the Early Minoan period

    Science.gov (United States)

    Cañellas-Boltà, N.; Riera-Mora, S.; Orengo, H. A.; Livarda, A.; Knappett, C.

    2018-03-01

    On the east Mediterranean island of Crete, a hierarchical society centred on large palatial complexes emerges during the Bronze Age. The economic basis for this significant social change has long been debated, particularly concerning the role of olive cultivation in the island's agricultural system. With the aim of studying vegetation changes and human management to understand the landscape history from Late Neolithic to Bronze Age, two palaeoenvironmental records have been studied at Kouremenos marsh, near the site of Palaikastro (Eastern Crete). Pollen, NPP and charcoal particles analyses evidenced seven phases of landscape change, resulting from different agricultural and pastoral practices and the use of fire probably to manage vegetation. Moreover, the Kouremenos records show the importance of the olive tree in the area. They reflect a clear trend for its increasing use and exploitation from 3600 cal yr BC (Final Neolithic) to the Early Minoan period, that is coeval with an opening of the landscape. The increase of Olea pollen was due to the expansion of the tree and its management using pruning and mechanical cleaning. The onset of olive expansion at c. 3600 cal yr BC places Crete among the first locales in the eastern Mediterranean in the management of this tree. Between c. 2780 and 2525 cal yr BC the landscape was largely occupied by olive and grasslands, coinciding with an increase in grazing practices. The high Olea pollen percentages (40-45%) suggest an intensive and large-scale exploitation of the olive tree. The results suggest that a complex and organized landscape with complementary land uses and activities was already in place since the Final Neolithic. The notable expansion of olive trees suggests the relevance of olive exploitation in the socio-economic development of Minoan towns of eastern Crete. Other crops, such as cereals and vine, and activities such as grazing have also played an important role in the configuration of the past landscape.

  20. Olive fly (Bactrocera oleae) activity, fruit infestation and temperature in an organic table olive orchard in southern Crete

    OpenAIRE

    Volakakis, Mr N.; Eyre, Dr M.D.; Kabourakis, Dr E.; Leifert, Prof C.

    2008-01-01

    Olive fly activity and olive fruit infestation was monitored in a table olive orchard in southern Crete throughout most of 2006 using McPhail traps. Flies were trapped weekly for 40 weeks, starting at the beginning of February. The fly data was split into 10 four-week periods. Male, female and total fly activity was significantly related to sampling period, maximum temperature and relative humidity but the pattern of catches was not consistent. Activity increased from February until July but ...

  1. A Novel Entropy-Based Centrality Approach for Identifying Vital Nodes in Weighted Networks

    Directory of Open Access Journals (Sweden)

    Tong Qiao

    2018-04-01

    Full Text Available Measuring centrality has recently attracted increasing attention, with algorithms ranging from those that simply calculate the number of immediate neighbors and the shortest paths to those that are complicated iterative refinement processes and objective dynamical approaches. Indeed, vital nodes identification allows us to understand the roles that different nodes play in the structure of a network. However, quantifying centrality in complex networks with various topological structures is not an easy task. In this paper, we introduce a novel definition of entropy-based centrality, which can be applicable to weighted directed networks. By design, the total power of a node is divided into two parts, including its local power and its indirect power. The local power can be obtained by integrating the structural entropy, which reveals the communication activity and popularity of each node, and the interaction frequency entropy, which indicates its accessibility. In addition, the process of influence propagation can be captured by the two-hop subnetworks, resulting in the indirect power. In order to evaluate the performance of the entropy-based centrality, we use four weighted real-world networks with various instance sizes, degree distributions, and densities. Correspondingly, these networks are adolescent health, Bible, United States (US airports, and Hep-th, respectively. Extensive analytical results demonstrate that the entropy-based centrality outperforms degree centrality, betweenness centrality, closeness centrality, and the Eigenvector centrality.

  2. Central neurocytoma: Management recommendations based on a 35-year experience

    International Nuclear Information System (INIS)

    Leenstra, James L.; Rodriguez, Fausto J.; Frechette, Christina M.; Giannini, Caterina; Stafford, Scott L.; Pollock, Bruce E.; Schild, Steven E.; Scheithauer, Bernd W.; Jenkins, Robert B.; Buckner, Jan C.; Brown, Paul D.

    2007-01-01

    Purpose: To examine the outcomes of patients with histologically confirmed central neurocytomas. Methods and Materials: The data from 45 patients with central neurocytomas diagnosed between 1971 and 2003 were retrospectively evaluated. Various combinations of surgery, radiotherapy (RT), and chemotherapy had been used for treatment. Results: The median follow-up was 10.0 years. The 10-year overall survival and local control rate was 83% and 60%, respectively. Patients whose tumor had a mitotic index of <3 (per 10 high-power fields) experienced a 10-year survival and local control rate of 89% and 74%, respectively, compared with 57% (p = 0.040) and 46% (p = 0.14) for patients with a tumor mitotic index of ≥3. The 10-year survival and local control rate was 90% and 74% for patients with typical tumors compared with 63% (p = 0.055) and 46% (p = 0.41) for those with atypical tumors. A comparison of gross total resection with subtotal resection showed no significant difference in survival or local control. Postoperative RT improved local control at 10 years (75% with RT vs. 51% without RT, p = 0.045); however, this did not translate into a survival benefit. No 1p19q deletions were found in the 19 tumors tested. Conclusion: Although the overall prognosis is quite favorable, one-third of patients experienced tumor recurrence or progression at 10 years, regardless of the extent of the initial resection. Postoperative RT significantly improved local control but not survival, most likely because of the effectiveness of salvage RT. For incompletely resected atypical tumors and/or those with a high mitotic index, consideration should be given to adjuvant RT because of the more aggressive nature

  3. A Study of the Groundwater Level Spatial Variability in the Messara Valley of Crete

    Science.gov (United States)

    Varouchakis, E. A.; Hristopulos, D. T.; Karatzas, G. P.

    2009-04-01

    The island of Crete (Greece) has a dry sub-humid climate and marginal groundwater resources, which are extensively used for agricultural activities and human consumption. The Messara valley is located in the south of the Heraklion prefecture, it covers an area of 398 km2, and it is the largest and most productive valley of the island. Over-exploitation during the past thirty (30) years has led to a dramatic decrease of thirty five (35) meters in the groundwater level. Possible future climatic changes in the Mediterranean region, potential desertification, population increase, and extensive agricultural activity generate concern over the sustainability of the water resources of the area. The accurate estimation of the water table depth is important for an integrated groundwater resource management plan. This study focuses on the Mires basin of the Messara valley for reasons of hydro-geological data availability and geological homogeneity. The research goal is to model and map the spatial variability of the basin's groundwater level accurately. The data used in this study consist of seventy (70) piezometric head measurements for the hydrological year 2001-2002. These are unevenly distributed and mostly concentrated along a temporary river that crosses the basin. The range of piezometric heads varies from an extreme low value of 9.4 meters above sea level (masl) to 62 masl, for the wet period of the year (October to April). An initial goal of the study is to develop spatial models for the accurate generation of static maps of groundwater level. At a second stage, these maps should extend the models to dynamic (space-time) situations for the prediction of future water levels. Preliminary data analysis shows that the piezometric head variations are not normally distributed. Several methods including Box-Cox transformation and a modified version of it, transgaussian Kriging, and Gaussian anamorphosis have been used to obtain a spatial model for the piezometric head. A

  4. Aerosol physical and optical properties in the Eastern Mediterranean Basin, Crete, from Aerosol Robotic Network data

    Directory of Open Access Journals (Sweden)

    A. Fotiadi

    2006-01-01

    Full Text Available In this study, we investigate the aerosol optical properties, namely aerosol extinction optical thickness (AOT, Angström parameter and size distribution over the Eastern Mediterranean Basin, using spectral measurements from the recently established FORTH (Foundation for Research and Technology-Hellas AERONET station in Crete, for the two-year period 2003–2004. The location of the FORTH-AERONET station offers a unique opportunity to monitor aerosols from different sources. Maximum values of AOT are found primarily in spring, which together with small values of the Angström parameter indicate dust transported from African deserts, whereas the minimum values of AOT occur in winter. In autumn, large AOT values observed at near-infrared wavelengths arise also from dust transport. In summer, large AOT values at ultraviolet (340 nm and visible wavelengths (500 nm, together with large values of the Angström parameter, are associated with transport of fine aerosols of urban/industrial and biomass burning origin. The Angström parameter values vary on a daily basis within the range 0.05–2.20, and on a monthly basis within the range 0.68–1.9. This behaviour, together with broad frequency distributions and back-trajectory analyses, indicates a great variety of aerosol types over the study region including dust, urban-industrial and biomass-burning pollution, and maritime, as well as mixed aerosol types. Large temporal variability is observed in AOT, Angström parameter, aerosol content and size. The fine and coarse aerosol modes persist throughout the year, with the coarse mode dominant except in summer. The highest values of AOT are related primarily to southeasterly winds, associated with coarse aerosols, and to a less extent to northwesterly winds associated with fine aerosols. The results of this study show that the FORTH AERONET station in Crete is well suited for studying the transport and mixing of different types of aerosols from a variety

  5. Coastal geomorphological study of pocket beaches in Crete, with the use of planview indices.

    Science.gov (United States)

    Alexandrakis, George; Karditsa, Aikaterini; Poulos, Serafim; Kampanis, Nikos

    2013-04-01

    The formation of pocket beaches is a result of a large number of processes and mechanisms that vary on space and time scales. This study aims in defining the planform characteristics of pocket beaches in Crete Isl. and to determine their sheltering effect, embaymentization and their status of equilibrium. Thus, data from 30 pocket beaches along the coastline of Crete, with different geomorphological and hydrodynamical setting, were collected. Planform parameters were applied and coastal planview indices from the bibliography were applied. The parameters included: length and orientation of the headlands between the pocket beach; length between the bay entrance and the center of the beach; lengths of the i) embayed shoreline, ii) embayed beach, iii) beach segment located at the shadow of a headland; linear distance and orientation between the edges of the embayed beach; direction of the incident wave energy flux; wave crest obliquity to the control line; beach area, maximum beach width and headland orientation and river/ torrent catchment areas in beach zones that an active river system existed (Bowman et al.2009). For the morphological mapping of the study areas, 1:5000 orthophoto maps were used. Wave regime has been calculated with the use of prognostic equations and utilising local wind data (mean annual frequency of wind speed and direction), provided by the Wind and Wave Atlas of the Eastern Mediterranean Sea. The diffraction and refraction of the waves has been simulated with the use of numerical models. The study shows that Cretan pocket beaches display a wide range of indentation, suggesting that is the result of several parameters that include tectonics, coastal hydrodynamics and river catchment areas. The more indented bays are, the shorter their beaches become, while low-indented pocket beaches are the widest and the longest ones. Beaches with headland with large length appear to be more protected and receive smaller amount of wave energy. Most of the

  6. An agent-based model of centralized institutions, social network technology, and revolution.

    Science.gov (United States)

    Makowsky, Michael D; Rubin, Jared

    2013-01-01

    This paper sheds light on the general mechanisms underlying large-scale social and institutional change. We employ an agent-based model to test the impact of authority centralization and social network technology on preference falsification and institutional change. We find that preference falsification is increasing with centralization and decreasing with social network range. This leads to greater cascades of preference revelation and thus more institutional change in highly centralized societies and this effect is exacerbated at greater social network ranges. An empirical analysis confirms the connections that we find between institutional centralization, social radius, preference falsification, and institutional change.

  7. Central air conditioning based on adsorption and solar energy

    International Nuclear Information System (INIS)

    Pralon Ferreira Leite, Antonio; Belo, Francisco Antonio; Martins, Moacir Machado; Bressan Riffel, Douglas

    2011-01-01

    This paper presents the characterization and the pre-dimensioning of an adsorption chiller as part of a 20 kW air conditioning central unit for cooling a set of rooms that comprises an area of 110 m 2 . The system is basically made up of a cold water storage tank supplied by an activated carbon-methanol adsorption chiller, a hot water storage tank, fed by solar energy and natural gas, and a fan-coil. During an acclimatization of 8 h (9-17 h), the following parameters were obtained for dimensioning the cooling system: 504 kg of activated carbon, 180 L of methanol, 7000 L of hot water, 10,300 L of cold water with its temperature varying in the fan-coil from 1 deg. C to 14 C. Considering the mean value of the total daily irradiation in Joao Pessoa (7 o 8'S, 34 o 50'WG), and a cover of regenerating heat supplied by solar energy equivalent to 70%, the adsorption chiller's expected coefficient of performance (COP) was found to be around 0.6.

  8. Central Decoding for Multiple Description Codes based on Domain Partitioning

    Directory of Open Access Journals (Sweden)

    M. Spiertz

    2006-01-01

    Full Text Available Multiple Description Codes (MDC can be used to trade redundancy against packet loss resistance for transmitting data over lossy diversity networks. In this work we focus on MD transform coding based on domain partitioning. Compared to Vaishampayan’s quantizer based MDC, domain based MD coding is a simple approach for generating different descriptions, by using different quantizers for each description. Commonly, only the highest rate quantizer is used for reconstruction. In this paper we investigate the benefit of using the lower rate quantizers to enhance the reconstruction quality at decoder side. The comparison is done on artificial source data and on image data. 

  9. A super base station based centralized network architecture for 5G mobile communication systems

    Directory of Open Access Journals (Sweden)

    Manli Qian

    2015-04-01

    Full Text Available To meet the ever increasing mobile data traffic demand, the mobile operators are deploying a heterogeneous network with multiple access technologies and more and more base stations to increase the network coverage and capacity. However, the base stations are isolated from each other, so different types of radio resources and hardware resources cannot be shared and allocated within the overall network in a cooperative way. The mobile operators are thus facing increasing network operational expenses and a high system power consumption. In this paper, a centralized radio access network architecture, referred to as the super base station (super BS, is proposed, as a possible solution for an energy-efficient fifth-generation (5G mobile system. The super base station decouples the logical functions and physical entities of traditional base stations, so different types of system resources can be horizontally shared and statistically multiplexed among all the virtual base stations throughout the entire system. The system framework and main functionalities of the super BS are described. Some key technologies for system implementation, i.e., the resource pooling, real-time virtualization, adaptive hardware resource allocation are also highlighted.

  10. Competencies for Central American SMEs in the Knowledge-Based ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Knowledge-based economy not only affects well developed countries but ... to the information and communication technologies (ICT) related competencies, as technologies plays a key and growing role in managing knowledge and exchange.

  11. Spa-goers’ Characteristics, Motivations, Preferences and Perceptions: Evidence from Elounda, Crete

    Directory of Open Access Journals (Sweden)

    Nikolaos Trihas

    2016-12-01

    Full Text Available Spa and wellness tourism is one of the fastest-growing market segments in the hospitality and tourism industry. The aim of this study is to investigate and identify spa-goers’ characteristics, motivations, preferences and perceptions, providing a better understanding of the main features of this type of tourists’ behavior and expectations from a spa and wellness centre. Primary quantitative research was conducted via a structured questionnaire in a sample of 123 spa customers at Elounda in Crete. The results of the study revealed a number of important factors that influence them when choosing a spa, namely the cleanliness and the maintenance of a spa, the staff knowledge and hygiene, the personnel behavior and courtesy, and the quality of services. In addition, the main reason for visiting the spa is for stress relief/relaxation, followed by physical health improvement and beauty treatments. Findings and discussion of this study are useful to industry practitioners (spa and wellness service providers who wish to develop appropriate marketing strategies and enhance customer satisfaction and academic researchers interested in spa and wellness tourism.

  12. Q fever in the Greek Island of Crete: epidemiologic, clinical, and therapeutic data from 98 cases.

    Science.gov (United States)

    Tselentis, Y; Gikas, A; Kofteridis, D; Kyriakakis, E; Lydataki, N; Bouros, D; Tsaparas, N

    1995-05-01

    A retrospective study was undertaken in Crete, Greece, to investigate the epidemiologic, clinical, and therapeutic aspects of Q fever. Over a period of 5 years (1989-1993), 1,298 patients were examined and 98 cases were identified. Individuals who were aged 20-29 years and 30-39 years appeared to have an increased risk of infection. Contact with animals was found to be a major risk factor for acquisition of Q fever. The predominant clinical manifestations of the infection were fever (91.7% of patients) and respiratory disease (88.5%), whereas hepatitis was the dominant feature in only a minority (7.1%) of patients. Chest radiographs frequently revealed pulmonary interstitial changes (36.4% of patients) and alveolar changes (34.4%). Abnormal echocardiographic findings were also observed. There was no difference in the duration of fever whether the patient received therapy with tetracycline or erythromycin, a finding that may be explained by the delay in initiating tetracycline therapy.

  13. Sustainable energy planning by using multi-criteria analysis application in the island of Crete

    International Nuclear Information System (INIS)

    Tsoutsos, Theocharis; Drandaki, Maria; Frantzeskaki, Niki; Iosifidis, Eleftherios; Kiosses, Ioannis

    2009-01-01

    The sustainable energy planning includes a variety of objectives, as the decision-making is directly related to the processes of analysis and management of different types of information (technological, environmental, economic and social). Very often, the traditional evaluation methods, such as the cost-benefit analysis and macro-economic indicators, are not sufficient to integrate all the elements included in an environmentally thorough energy plan. On the contrary the multiple criteria methods provide a tool, which is more appropriate to assemble and to handle a wide range of variables that is evaluated in different ways and thus offer valid decision support. This paper exploits the multi-criteria methodology for the sustainable energy planning on the island of Crete in Greece. A set of energy planning alternatives are determined upon the implementation of installations of renewable energy sources on the island and are assessed against economic, technical, social and environmental criteria identified by the actors involved in the energy planning arena. The study constitutes an exploratory analysis with the potential to assist decision makers responsible for regional energy planning, providing them the possibility of creating classifications of alternative sustainable energy alternatives.

  14. Orientations of the Bronze Age Villa Complex at Vathypetro in Crete

    Science.gov (United States)

    Blomberg, M.; Henriksson, G.

    We present the results of our archaeoastronomical study of the villa and the tripartite shrine at Vathypetro. We found orientations to three major celestial events (counting the equinoxes as one): to sunrise at the equinoxes and the winter solstice in the case of the villa and to sunset at the summer solstice in the case of the tripartite stone. The axis of symmetry of the major room of the villa was oriented to sunrise of the 22nd of October in the Late Minoan period. This was also the orientation of the axis of symmetry of the main cult room in the west wing of the palace at Malia. We propose that this orientation marked the time for planting and thus the beginning of the agricultural year. It is unusual that archaeoastronomical studies make contributions to historical debates. However certain orientations dating after Late Minoan I seem to reflect the Mycenaean presence in Crete. The orientation of the tripartite shrine to sunset at the summer solstice is the same as the orientations of the small shrines at Malia and Agia Triada, all of which we argue to have been built for Mycenaeans. We propose that there are two types of orientations in the island: those to the east within the limits for sunrise - made by Minoans, and some to the west - made by (or for) Mycenaeans.

  15. Evaluation of comfort conditions in urban open spaces. Application in the island of Crete

    International Nuclear Information System (INIS)

    Tsitoura, Marianna; Tsoutsos, Theocharis; Daras, Tryfon

    2014-01-01

    Highlights: • Outdoor spaces field surveys carried out in four different urban open spaces. • A strong connection between the microclimate and the use of open space. • Human physical and psychological factors can optimize the urban space design. - Abstract: The thermal environment in outdoor public spaces and their level of use are strongly connected. The design of outdoor spaces, especially in urban areas, is very critical in Southern Europe due to their extended use during summertime where the urban heat island phenomenon deteriorates the microclimatic conditions. In this paper the main outcomes of outdoor spaces field surveys are presented, which were carried out in four different urban open spaces in Crete. On site measurements were implemented and a questionnaire was used in order to estimate the thermal comfort of visitors. Thermal indices like Predicted Mean Vote, Physiologically Equivalent Temperature, Standard Effective Temperature, Wet Bulb Globe Temperature are used to evaluate the features of urban microclimate and then are being compared in order to find the most suitable for the Mediterranean microclimate. This suggests another way of approach to the researcher and provides essential tools to the designer

  16. A Field-Based Aquatic Life Benchmark for Conductivity in Central Appalachian Streams (Final Report)

    Science.gov (United States)

    EPA announced the availability of the final report, A Field-Based Aquatic Life Benchmark for Conductivity in Central Appalachian Streams. This report describes a method to characterize the relationship between the extirpation (the effective extinction) of invertebrate g...

  17. Αutomated 2D shoreline detection from coastal video imagery: an example from the island of Crete

    Science.gov (United States)

    Velegrakis, A. F.; Trygonis, V.; Vousdoukas, M. I.; Ghionis, G.; Chatzipavlis, A.; Andreadis, O.; Psarros, F.; Hasiotis, Th.

    2015-06-01

    Beaches are both sensitive and critical coastal system components as they: (i) are vulnerable to coastal erosion (due to e.g. wave regime changes and the short- and long-term sea level rise) and (ii) form valuable ecosystems and economic resources. In order to identify/understand the current and future beach morphodynamics, effective monitoring of the beach spatial characteristics (e.g. the shoreline position) at adequate spatio-temporal resolutions is required. In this contribution we present the results of a new, fully-automated detection method of the (2-D) shoreline positions using high resolution video imaging from a Greek island beach (Ammoudara, Crete). A fully-automated feature detection method was developed/used to monitor the shoreline position in geo-rectified coastal imagery obtained through a video system set to collect 10 min videos every daylight hour with a sampling rate of 5 Hz, from which snapshot, time-averaged (TIMEX) and variance images (SIGMA) were generated. The developed coastal feature detector is based on a very fast algorithm using a localised kernel that progressively grows along the SIGMA or TIMEX digital image, following the maximum backscatter intensity along the feature of interest; the detector results were found to compare very well with those obtained from a semi-automated `manual' shoreline detection procedure. The automated procedure was tested on video imagery obtained from the eastern part of Ammoudara beach in two 5-day periods, a low wave energy period (6-10 April 2014) and a high wave energy period (1 -5 November 2014). The results showed that, during the high wave energy event, there have been much higher levels of shoreline variance which, however, appeared to be similarly unevenly distributed along the shoreline as that related to the low wave energy event, Shoreline variance `hot spots' were found to be related to the presence/architecture of an offshore submerged shallow beachrock reef, found at a distance of 50-80 m

  18. Centralized computer-based controls of the Nova Laser Facility

    International Nuclear Information System (INIS)

    Krammen, J.

    1985-01-01

    This article introduces the overall architecture of the computer-based Nova Laser Control System and describes its basic components. Use of standard hardware and software components ensures that the system, while specialized and distributed throughout the facility, is adaptable. 9 references, 6 figures

  19. Competencies for Central American SMEs in the Knowledge-Based ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Knowledge-based economy not only affects well developed countries but also the performance and possibilities of small economic actors positioned on less developed countries. Micro, small and medium enterprises - characterized by low financial and human capital - are also exposed to the opportunities and risks ...

  20. The importance of geological data and derived information in seismic response assessment for urban sites. An example from the Island of Crete, Greece

    Science.gov (United States)

    Tsangaratos, Paraskevas; Loupasakis, Constantinos; Rozos, Dimitrios; Rondoyianni, Theodora; Vafidis, Antonios; Savvaidis, Alexandros; Soupios, Pantelis; Papadopoulos, Nikos; Sarris, Apostolos

    2015-04-01

    The magnitude, frequency content and duration of an earthquake ground motion depends mainly on the surrounding geological, tectonic and geomorphological conditions. Numerous reports have been contacted illustrating the necessity of providing accurate geological information in order to estimate the level of seismic hazard. In this context, geological information is the outcome of processing primary, raw field data and geotechnical investigation data that are non - organized and associated with the geological model of the study area. In most cases, the geological information is provided as an advance element, a key component of the "function" that solves any geo-environmental problem and is primarily reflected on analogue or digital maps. The main objective of the present study is to illustrate the importance of accurate geological information in the thirteen (13) selected sites of the Hellenic Accelerometric Network (HAN) in the area of Crete Island, in order to estimate the seismic action according to Eurocode (EC8). As an example the detailed geological-geotechnical map of the area around HAN site in Rethymno city, Crete is presented. The research area covers a 250m radius surrounding the RTHE HAN-station at a scale of 1: 2000 with detail description of the geological and geotechnical characteristics of the formations as well as the tectonic features (cracks, upthrust, thrust, etc) of the rock mass. The field survey showed that the RTHE station is founded over limestones and dolomites formations. The formations exhibit very good geomechanical behaviour; however they present extensive fragmentation and karstification. At this particular site the identification of a fault nearby the station proved to be significant information for the geophysical research as the location and orientation of the tectonic setting provided new perspective on the models of seismic wave prorogation. So, the geological data and the induced information along with the tectonic structure of

  1. Uniformity testing: assessment of a centralized web-based uniformity analysis system.

    Science.gov (United States)

    Klempa, Meaghan C

    2011-06-01

    Uniformity testing is performed daily to ensure adequate camera performance before clinical use. The aim of this study is to assess the reliability of Beth Israel Deaconess Medical Center's locally built, centralized, Web-based uniformity analysis system by examining the differences between manufacturer and Web-based National Electrical Manufacturers Association integral uniformity calculations measured in the useful field of view (FOV) and the central FOV. Manufacturer and Web-based integral uniformity calculations measured in the useful FOV and the central FOV were recorded over a 30-d period for 4 cameras from 3 different manufacturers. These data were then statistically analyzed. The differences between the uniformity calculations were computed, in addition to the means and the SDs of these differences for each head of each camera. There was a correlation between the manufacturer and Web-based integral uniformity calculations in the useful FOV and the central FOV over the 30-d period. The average differences between the manufacturer and Web-based useful FOV calculations ranged from -0.30 to 0.099, with SD ranging from 0.092 to 0.32. For the central FOV calculations, the average differences ranged from -0.163 to 0.055, with SD ranging from 0.074 to 0.24. Most of the uniformity calculations computed by this centralized Web-based uniformity analysis system are comparable to the manufacturers' calculations, suggesting that this system is reasonably reliable and effective. This finding is important because centralized Web-based uniformity analysis systems are advantageous in that they test camera performance in the same manner regardless of the manufacturer.

  2. Regional scale hydrologic modeling of a karst-dominant geomorphology: The case study of the Island of Crete

    Science.gov (United States)

    Malagò, Anna; Efstathiou, Dionissios; Bouraoui, Fayçal; Nikolaidis, Nikolaos P.; Franchini, Marco; Bidoglio, Giovanni; Kritsotakis, Marinos

    2016-09-01

    Crete Island (Greece) is a karst dominated region that faces limited water supply and increased seasonal demand, especially during summer for agricultural and touristic uses. In addition, due to the mountainous terrain, interbasin water transfer is very limited. The resulting water imbalance requires a correct quantification of available water resources in view of developing appropriate management plans to face the problem of water shortage. The aim of this work is the development of a methodology using the SWAT model and a karst-flow model (KSWAT, Karst SWAT model) for the quantification of a spatially and temporally explicit hydrologic water balance of karst-dominated geomorphology in order to assess the sustainability of the actual water use. The application was conducted in the Island of Crete using both hard (long time series of streamflow and spring monitoring stations) and soft data (i.e. literature information of individual processes). The KSWAT model estimated the water balance under normal hydrological condition as follows: 6400 Mm3/y of precipitation, of which 40% (2500 Mm3/y) was lost through evapotranspiration, 5% was surface runoff and 55% percolated into the soil contributing to lateral flow (2%), and recharging the shallow (9%) and deep aquifer (44%). The water yield was estimated as 22% of precipitation, of which about half was the contribution from spring discharges (9% of precipitation). The application of the KSWAT model increased our knowledge about water resources availability and distribution in Crete under different hydrologic conditions. The model was able to capture the hydrology of the karst areas allowing a better management and planning of water resources under scarcity.

  3. Present and future responses of growing degree days for Crete Island in Greece

    Science.gov (United States)

    Paparrizos, Spyridon; Matzarakis, Andreas

    2017-02-01

    Climate affects practically all the physiological processes that determine plant life (IPCC, 2014). A major challenge and objective of the agricultural science is to predict the occurrences of specific physical or biological events. For this reason, flower phenology has been widely used to study the flowering in plant species of economic interest, and in this concept, temperature and heat units have been widely accepted as the most important factors affecting processes leading to flowering. The determination of heat requirements in the first developing phases of plants has been expressed as Growing Degree Days (GDD). Determination of GDD is useful for achieving a better understanding of the flowering season development in several plant species, and for forecasting when flowering will occur (Paparrizos and Matzarakis, 2017). Temperature and GDD represent two important spatially-dynamic climatic variables, as they both play vital roles in influencing forest development by directly affecting plant functions such as evapotranspiration, photosynthesis and plant transpiration. Understanding the spatial distribution of GDD is crucial to the practice of sustainable agricultural and forest management, as GDD relates to the integration of growth and provides precise point estimates (Hasan et al., 2007; Matzarakis et al., 2007). The aim of the current study was to estimate and map through downscaling spatial interpolation and multi-linear regression techniques, the future variation of GDD for the periods 2021-2050 and 2071-2100, under the A1B and B1 IPCC emission scenarios in relation with the reference periods for Crete Island in Greece. Future temperature data were obtained, validated and analysed from the ENSEMBLES European project. A combination of dynamical and statistical approach was conducted in order to downscale and perform the spatial interpolation of GDD through ArcGIS 10.2.1. The results indicated that in the future, GDD will be increased and the existing

  4. Centralizing Data Management with Considerations of Uncertainty and Information-Based Flexibility

    OpenAIRE

    Velu, Chander K.; Madnick, Stuart E.; Van Alstyne, Marshall W.

    2013-01-01

    This paper applies the theory of real options to analyze how the value of information-based flexibility should affect the decision to centralize or decentralize data management under low and high uncertainty. This study makes two main contributions. First, we show that in the presence of low uncertainty, centralization of data management decisions creates more total surplus for the firm as the similarity of business units increases. In contrast, in the presence of high uncertainty, centraliza...

  5. Centralized light-source optical access network based on polarization multiplexing.

    Science.gov (United States)

    Grassi, Fulvio; Mora, José; Ortega, Beatriz; Capmany, José

    2010-03-01

    This paper presents and demonstrates a centralized light source optical access network based on optical polarization multiplexing technique. By using two optical sources emitting light orthogonally polarized in the Central Node for downstream and upstream operations, the Remote Node is kept source-free. EVM values below telecommunication standard requirements have been measured experimentally when bidirectional digital signals have been transmitted over 10 km of SMF employing subcarrier multiplexing technique in the electrical domain.

  6. Caribbean and Central American Women's Feminist Inquiry through Theater-Based Action Research

    Science.gov (United States)

    Sánchez Ares, Rocío

    2015-01-01

    Feminist action research interrogates gendered dynamics in the development of a collective consciousness. A group of immigrant Latina women (Latinas) from the Caribbean and Central America employed community-based theater as an instrument to mobilize diverse audiences against discriminatory practices and policies. Based on their theater work, I…

  7. SACFIR: SDN-Based Application-Aware Centralized Adaptive Flow Iterative Reconfiguring Routing Protocol for WSNs.

    Science.gov (United States)

    Aslam, Muhammad; Hu, Xiaopeng; Wang, Fan

    2017-12-13

    Smart reconfiguration of a dynamic networking environment is offered by the central control of Software-Defined Networking (SDN). Centralized SDN-based management architectures are capable of retrieving global topology intelligence and decoupling the forwarding plane from the control plane. Routing protocols developed for conventional Wireless Sensor Networks (WSNs) utilize limited iterative reconfiguration methods to optimize environmental reporting. However, the challenging networking scenarios of WSNs involve a performance overhead due to constant periodic iterative reconfigurations. In this paper, we propose the SDN-based Application-aware Centralized adaptive Flow Iterative Reconfiguring (SACFIR) routing protocol with the centralized SDN iterative solver controller to maintain the load-balancing between flow reconfigurations and flow allocation cost. The proposed SACFIR's routing protocol offers a unique iterative path-selection algorithm, which initially computes suitable clustering based on residual resources at the control layer and then implements application-aware threshold-based multi-hop report transmissions on the forwarding plane. The operation of the SACFIR algorithm is centrally supervised by the SDN controller residing at the Base Station (BS). This paper extends SACFIR to SDN-based Application-aware Main-value Centralized adaptive Flow Iterative Reconfiguring (SAMCFIR) to establish both proactive and reactive reporting. The SAMCFIR transmission phase enables sensor nodes to trigger direct transmissions for main-value reports, while in the case of SACFIR, all reports follow computed routes. Our SDN-enabled proposed models adjust the reconfiguration period according to the traffic burden on sensor nodes, which results in heterogeneity awareness, load-balancing and application-specific reconfigurations of WSNs. Extensive experimental simulation-based results show that SACFIR and SAMCFIR yield the maximum scalability, network lifetime and stability

  8. SACFIR: SDN-Based Application-Aware Centralized Adaptive Flow Iterative Reconfiguring Routing Protocol for WSNs

    Directory of Open Access Journals (Sweden)

    Muhammad Aslam

    2017-12-01

    Full Text Available Smart reconfiguration of a dynamic networking environment is offered by the central control of Software-Defined Networking (SDN. Centralized SDN-based management architectures are capable of retrieving global topology intelligence and decoupling the forwarding plane from the control plane. Routing protocols developed for conventional Wireless Sensor Networks (WSNs utilize limited iterative reconfiguration methods to optimize environmental reporting. However, the challenging networking scenarios of WSNs involve a performance overhead due to constant periodic iterative reconfigurations. In this paper, we propose the SDN-based Application-aware Centralized adaptive Flow Iterative Reconfiguring (SACFIR routing protocol with the centralized SDN iterative solver controller to maintain the load-balancing between flow reconfigurations and flow allocation cost. The proposed SACFIR’s routing protocol offers a unique iterative path-selection algorithm, which initially computes suitable clustering based on residual resources at the control layer and then implements application-aware threshold-based multi-hop report transmissions on the forwarding plane. The operation of the SACFIR algorithm is centrally supervised by the SDN controller residing at the Base Station (BS. This paper extends SACFIR to SDN-based Application-aware Main-value Centralized adaptive Flow Iterative Reconfiguring (SAMCFIR to establish both proactive and reactive reporting. The SAMCFIR transmission phase enables sensor nodes to trigger direct transmissions for main-value reports, while in the case of SACFIR, all reports follow computed routes. Our SDN-enabled proposed models adjust the reconfiguration period according to the traffic burden on sensor nodes, which results in heterogeneity awareness, load-balancing and application-specific reconfigurations of WSNs. Extensive experimental simulation-based results show that SACFIR and SAMCFIR yield the maximum scalability, network lifetime

  9. What makes you more central? : antecedents of changes in betweenness-centrality in technology-based alliance networks

    NARCIS (Netherlands)

    Gilsing, V.A.; Cloodt, M.M.A.H.; Bertrand-Cloodt, D.A.M.

    2016-01-01

    Although central network positions have been associated with above average performance effects, an important void that still remains is how firms come to occupy a more central position in the first place. Whereas recently made exogenous explanations have shed some more light on aggregate changes in

  10. Is Kissamos Bay in NW Crete, Greece worth to be exploited as a marine aggregates deposit? An integrated approach

    Science.gov (United States)

    Anastasatou, Marianthi; Tsoutsia, Antonia; Petrakis, Stelios; Rousakis, Grigoris; Karditsa, Aikaterini; Hasiotis, Thomas; Kapsimalis, Vasilios; Poulos, Serafim; Stamatakis, Michael

    2017-04-01

    This study uses an integrated approach to investigate the offshore area of Kissamos Bay, NW Crete Island, Greece, as a prospective marine aggregate (MA) deposit. Non-fuel marine minerals and especially marine aggregates (sand and gravel) are reviewed from the perspective of resources during the last decades. The possible MA deposit of Kissamos Bay was explored during the implementation of the research project THALES-MARE, considering existing information of previous extraction activities in the wider area. Kissamos Bay is located at the inner continental shelf off NW Crete. The onshore basement rocks are composed of Mesozoic to Eocene limestones, shale and sandstone units, along with Neogene sediments such as marls, sandstones and claystones, which locally host Messinian gypsum layers. Sixteen sea-bottom sediment samples were collected with a Smith-McIntyretype grab along four transects, vertical to the shoreline, at water depths of 11 to 44m. A sub-bottom acoustic profiler survey was conducted in order to quantitatively determine the deposit (dimensions and structure). Mineralogical, geochemical, sedimentological and benthic analyses of the samples were carried out, in order to determine the quality of the reservoir and the environmental impact of a potential exploitation. Mineralogical results indicated that the bulk samples consist predominantly of quartz, while calcite occurs as a second significant phase. Chemical analysis of major and trace elements revealed that the average SiO2 content is around 55% with samples closer to the beach (depths Culture and Sports.

  11. Sizing and Optimization for Hybrid Central in South Algeria Based on Three Different Generators

    Directory of Open Access Journals (Sweden)

    Chouaib Ammari

    2017-11-01

    Full Text Available In this paper, we will size an optimum hybrid central content three different generators, two on renewable energy (solar photovoltaic and wind power and two nonrenewable (diesel generator and storage system because the new central generator has started to consider the green power technology in order for best future to the world, this central will use all the green power resource available and distributes energy to a small isolated village in southwest of Algeria named “Timiaouine”. The consumption of this village estimated with detailed in two season; season low consumption (winter and high consumption (summer, the hybrid central will be optimized by program Hybrid Optimization Model for Electric Renewable (HOMER PRO, this program will simulate in two configuration, the first with storage system, the second without storage system and in the end the program HOMER PRO will choose the best configuration which is the mixture of both economic and ecologic configurations, this central warrants the energetic continuity of village. Article History: Received May 18th 2017; Received in revised form July 17th 2017; Accepted Sept 3rd 2017; Available online How to Cite This Article: Ammari, C., Hamouda,M., and Makhloufi,S. (2017 Sizing and Optimization for Hybrid Central in South Algeria Based on Three Different Generators. International Journal of Renewable Energy Development, 6(3, 263-272. http://doi.org/10.14710/ijred.6.3.263-272

  12. Designing the central knowledge base for the purposes of final works in architecture

    Directory of Open Access Journals (Sweden)

    Aleksić Ljiljana

    2014-01-01

    Full Text Available The solution for many issues related to the selection of construction products, currently present on the market, could be a Central knowledge base, consisting of verified and reliable data of construction products. Beside previous participants: investor, architect and contractor, that were involved in the processes of design and construction, herein is equally introduced manufacturer construction materials and products. The Central knowledge base consists of: a catalog sheets of the graphics base, alphanumeric base and base with textual data, and represents a flexible system that is subject to amendments. It is built to support architects during processes design and construction, as well as for education of students attending subject Final works at the Faculty of Civil Engineering in Subotica.

  13. Stratigraphy of Neogene deposits in the Rethymnon Province, Crete, with special reference to the phylogeny of uniserial Uvigerina from the Mediterranean region

    NARCIS (Netherlands)

    Meulenkamp, J.E.

    1969-01-01

    Stratigraphical and micropaleontological investigations were performed on Neogene deposits of the Rethymnon Province, Western Crete. The Neogene succession includes marine as well as brackish and fresh-water sediments. Eight formations are recognized, several of which have to be regarded as

  14. Low prevalence of liver-kidney microsomal autoantibodies of type 1 (LKM1) in hepatitis C seropositive subjects on Crete, Greece.

    Science.gov (United States)

    Drygiannakis, D; Lionis, C; Drygiannakis, I; Pappas, G; Kouroumalis, E

    2001-01-01

    Hepatitis C is a serious problem on the Greek island of Crete, where a high prevalence of antibodies against hepatitis C (anti-HCV) has recently been reported. This article reports the findings of a study carried out in Crete, which investigated the prevalence of serum autoantibodies in patients with chronic hepatitis C. One hundred and forty two patients (59 men and 83 women), who were found anti-HCV seropositive in two hospitals and two Primary Health Care Centres in Crete, were eligible. Sixty healthy blood donors (46 men, 14 women), which were negative to anti-HCV, were used as the control group. They were randomly selected from those attending Rethymnon Hospital. Autoantibodies were identified using the indirect immunofluorescence (IFL) technique on human epithelial cells from larynx cancer (HEp-2 cells), rat liver-kidney-stomach substrate (CT3) and Chrithidia Luciliae (CL). Serum autoantibodies were detected in 104 HCV patients, yielding an overall prevalence of 73.2%. The most frequent autoantibodies were antinuclear antibodies (ANA), positive in 72 patients (50.7%). Anti-smooth muscle antibodies (ASMA) were detected in 33 patients (23.2%). Only one patient was positive for LKM1 autoantibodies. No autoantibodies were found in 38 patients (26.7%). Autoantibodies were also found in 5 out of the 60 examined healthy blood donors (8.3%). Autoantibodies, mainly ANA and ASMA are very common in HCV seropositive patients from Crete. By contrast LKM1 autoantibodies are exceptionally rare in these patients.

  15. Goat-based aid programme in Central Java: An effective intervention for the poor and vulnerable?

    NARCIS (Netherlands)

    Budisatria, I.G.S.; Udo, H.M.J.

    2013-01-01

    This study evaluated a goat-based aid programme developed to facilitate the recovery of vulnerable people in an earthquake affected area in Central Java, Indonesia. Farmers, organised in farmers’ groups, received a package of one male and four female goats. In total, 72 farmers from 6 farmers’

  16. Cultivating Urban Naturalists: Teaching Experiential, Place-Based Learning through Nature Journaling in Central Park

    Science.gov (United States)

    Warkentin, Traci

    2011-01-01

    Preservice educators engaged in experiential, place-based learning through a semester-long assignment in which they observed a specific place in Central Park in Manhattan, New York, and kept a nature journal. The assignment was organized around two pivotal elements: direct, sensory experience and time in place. Both elements added vital dimensions…

  17. Understanding Urban Spatial Structure of Shanghai Central City Based on Mobile Phone Data

    Institute of Scientific and Technical Information of China (English)

    Niu; Xinyi; Ding; Liang; Song; Xiaodong; Zhang; Qingfei

    2015-01-01

    Taking Shanghai Central City as its case study, this paper presents an approach to exploring the urban spatial structure through mobile phone positioning data. Firstly, based on base station location data and mobile phone signaling data, the paper analyses the number of users connecting to each base station, and further generates the maps of mobile phone user density through kernel density analysis. We move on to calculate the multi-day average user density based on a time frame of 10:00 and 23:00 at workdays and 15:00 and 23:00 at weekends for Shanghai Central City. Then, through spatial aggregation and density classifi cation on the density maps of 10:00 at workdays and 15:00 at weekends, we identify the ranks and functions of public centers within Shanghai Central City. Lastly, we identify residential areas, business off ice areas, and leisure areas in Shanghai Central City and measure the degree of functional mix by comparing the ratio of day and night user density as well as the user density at nighttime of workdays and weekends.

  18. Lyapunov-Based Control Scheme for Single-Phase Grid-Connected PV Central Inverters

    NARCIS (Netherlands)

    Meza, C.; Biel, D.; Jeltsema, D.; Scherpen, J. M. A.

    A Lyapunov-based control scheme for single-phase single-stage grid-connected photovoltaic central inverters is presented. Besides rendering the closed-loop system globally stable, the designed controller is able to deal with the system uncertainty that depends on the solar irradiance. A laboratory

  19. BridgeRank: A novel fast centrality measure based on local structure of the network

    Science.gov (United States)

    Salavati, Chiman; Abdollahpouri, Alireza; Manbari, Zhaleh

    2018-04-01

    Ranking nodes in complex networks have become an important task in many application domains. In a complex network, influential nodes are those that have the most spreading ability. Thus, identifying influential nodes based on their spreading ability is a fundamental task in different applications such as viral marketing. One of the most important centrality measures to ranking nodes is closeness centrality which is efficient but suffers from high computational complexity O(n3) . This paper tries to improve closeness centrality by utilizing the local structure of nodes and presents a new ranking algorithm, called BridgeRank centrality. The proposed method computes local centrality value for each node. For this purpose, at first, communities are detected and the relationship between communities is completely ignored. Then, by applying a centrality in each community, only one best critical node from each community is extracted. Finally, the nodes are ranked based on computing the sum of the shortest path length of nodes to obtained critical nodes. We have also modified the proposed method by weighting the original BridgeRank and selecting several nodes from each community based on the density of that community. Our method can find the best nodes with high spread ability and low time complexity, which make it applicable to large-scale networks. To evaluate the performance of the proposed method, we use the SIR diffusion model. Finally, experiments on real and artificial networks show that our method is able to identify influential nodes so efficiently, and achieves better performance compared to other recent methods.

  20. Characterization of carbonaceous aerosols during the MINOS campaign in Crete, July–August 2001: a multi-analytical approach

    Directory of Open Access Journals (Sweden)

    J. Sciare

    2003-01-01

    Full Text Available During the major part of the Mediterranean Intensive Oxidant Study (MINOS campaign (summer 2001, Crete Isl., the Marine Boundary Layer (MBL air was influenced by long range transport of biomass burning from the northern and western part of the Black Sea. During this campaign, carbonaceous aerosols were collected on quartz filters at a Free Tropospheric (FT site, and at a MBL site together with size-resolved distribution of aerosols. Three Evolution Gas Analysis (EGA protocols have been tested in order to better characterize the collected aged biomass burning smoke: A 2-step thermal method (Cachier et al., 1989 and a thermo-optical technique using two different temperature programs. The later temperature programs are those used for IMPROVE (Interagency Monitoring of Protected Visual Environments and NIOSH 5040 (National Institute of Occupational Safety and Health. Artifacts were observed using the NIOSH temperature program and identified as interactions between carbon and dust deposited on the filter matrix at high temperature (T>550ºC under the pure helium step of the analysis. During the MINOS campaign, Black Carbon (BC and Organic Carbon (OC mass concentrations were on average respectively 1.19±0.56 and 3.62±1.08 mgC/m3 for the IMPROVE temperature program, and 1.09±0.36 and 3.75±1.24 mgC/m3 for the thermal method. Though these values compare well on average and the agreement between the Total Carbon (TC measurements sample to sample was excellent (slope=1.00, r2=0.93, n=56, important discrepancies were observed in determining BC concentrations from these two methods (average error of 33±22%. BC from the IMPROVE temperature program compared well with non-sea-salt potassium (nss-K pointing out an optical sensitivity to biomass burning. On the other hand, BC from the thermal method showed a better agreement with non-sea-salt sulfate (nss-SO4, considered as a tracer for fossil fuel combustion during the MINOS campaign. The coupling between

  1. Contemporary approaches to reducing the risks of central counterparties based on the use of marginal contributions

    Directory of Open Access Journals (Sweden)

    Utkin Viktor Sergeyevich

    2012-07-01

    Full Text Available To protect their own interests central counterparties has developed a number of procedures, including payment of guarantee margin by trading members as a means to ensure their positions. This article discusses a number of approaches, which attempt to simulate the risks of the Central Committee, as well as calculating the amount of margin and other resources in the event of insolvency. These approaches are based on the simulation of the three main types: (a statistical modeling; (b optimization modeling, and (c model of option pricing. The author incorporates the basic provisions of models.

  2. Prevalence of metabolic syndrome in Central America: a cross-sectional population-based study

    Directory of Open Access Journals (Sweden)

    Roy A. Wong-McClure

    2015-09-01

    Full Text Available OBJECTIVE: To report the prevalence of metabolic syndrome (MetS as found by the Central American Diabetes Initiative (CAMDI study for five major Central American populations: Belize (national; Costa Rica (San José; Guatemala (Guatemala City; Honduras (Tegucigalpa; and Nicaragua (Managua. METHODS: Study data on 6 185 adults aged 20 years or older with anthropometric and laboratory determination of MetS from population-based surveys were analyzed. Overall, the survey response rate was 82.0%. MetS prevalence was determined according to criteria from the Adult Treatment Panel III of the National Cholesterol Education Program. The study's protocol was reviewed and approved by the bioethical committee of each country studied. RESULTS: The overall standardized prevalence of MetS in the Central American region was 30.3% (95% confidence interval (CI: 27.1-33.4. There was wide variability by gender and work conditions, with higher prevalence among females and unpaid workers. The standardized percentage of the population free of any component of MetS was lowest in Costa Rica (9.0%; CI: 6.5-11.4 and highest in Honduras (21.1%; CI: 16.4-25.9. CONCLUSIONS: Overall prevalence of MetS in Central America is high. Strengthening surveillance of chronic diseases and establishing effective programs for preventing cardiovascular diseases might reduce the risk of MetS in Central America.

  3. Maternal depression and personality traits in association with child neuropsychological and behavioral development in preschool years: Mother-child cohort (Rhea Study) in Crete, Greece.

    Science.gov (United States)

    Koutra, Katerina; Roumeliotaki, Theano; Kyriklaki, Andriani; Kampouri, Mariza; Sarri, Katerina; Vassilaki, Maria; Bitsios, Panos; Kogevinas, Manolis; Chatzi, Leda

    2017-08-01

    Poor perinatal maternal mental health has been linked with negative outcomes on early child development; however, the importance of maternal personality has been neglected thus far. We aimed to examine the effects of antenatal and postnatal maternal mental health, including assessment of maternal personality characteristics, on child neuropsychological and behavioral development at preschool years in a population based mother-child cohort (Rhea Study) in Crete, Greece. Self-reported measures of maternal depression (EPDS), trait anxiety (STAI-Trait) and personality traits (EPQ-R) were assessed in a sample of 288 women at 28-32 weeks of gestation. A larger sample of 642 mothers completed the EPDS scale at 8 weeks postpartum. Children's neuropsychological (MSCA) and behavioral (ADHDT and SDQ) development were assessed at 4 years of age. Linear regression analyses were used to estimate the associations between the exposures and outcomes of interest after adjustment for potential confounders. Regarding child neuropsychological development, increased postnatal depressive symptoms were associated with child's perceptual performance, whereas increased maternal psychoticism was linked with child's motor ability at 4 years of age. Furthermore, elevated levels of maternal depression during pregnancy and postpartum, and the predisposing personality characteristics of trait anxiety and neuroticism, were associated with children's behavioral difficulties. A clinical diagnostic instrument for maternal mental health was not used and assessment of children's behavior was based on maternal report. These findings suggest that poor perinatal maternal mental health and an adverse personality profile may be associated with impaired child neuropsychological and behavioral development at preschool years. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Concordance-based Kendall's Correlation for Computationally-Light vs. Computationally-Heavy Centrality Metrics: Lower Bound for Correlation

    Directory of Open Access Journals (Sweden)

    Natarajan Meghanathan

    2017-01-01

    Full Text Available We identify three different levels of correlation (pair-wise relative ordering, network-wide ranking and linear regression that could be assessed between a computationally-light centrality metric and a computationally-heavy centrality metric for real-world networks. The Kendall's concordance-based correlation measure could be used to quantitatively assess how well we could consider the relative ordering of two vertices vi and vj with respect to a computationally-light centrality metric as the relative ordering of the same two vertices with respect to a computationally-heavy centrality metric. We hypothesize that the pair-wise relative ordering (concordance-based assessment of the correlation between centrality metrics is the most strictest of all the three levels of correlation and claim that the Kendall's concordance-based correlation coefficient will be lower than the correlation coefficient observed with the more relaxed levels of correlation measures (linear regression-based Pearson's product-moment correlation coefficient and the network wide ranking-based Spearman's correlation coefficient. We validate our hypothesis by evaluating the three correlation coefficients between two sets of centrality metrics: the computationally-light degree and local clustering coefficient complement-based degree centrality metrics and the computationally-heavy eigenvector centrality, betweenness centrality and closeness centrality metrics for a diverse collection of 50 real-world networks.

  5. The new Central American seismic hazard zonation: Mutual consensus based on up to day seismotectonic framework

    Science.gov (United States)

    Alvarado, Guillermo E.; Benito, Belén; Staller, Alejandra; Climent, Álvaro; Camacho, Eduardo; Rojas, Wilfredo; Marroquín, Griselda; Molina, Enrique; Talavera, J. Emilio; Martínez-Cuevas, Sandra; Lindholm, Conrad

    2017-11-01

    Central America is one of the most active seismic zones in the World, due to the interaction of five tectonic plates (North America, Caribbean, Coco, Nazca and South America), and its internal deformation, which generates almost one destructive earthquakes (5.4 ≤ Mw ≤ 8.1) every year. A new seismological zonation for Central America is proposed based on seismotectonic framework, a geological context (tectonic and geological maps), geophysical and geodetic evidence (gravimetric maps, magnetometric, GPS observations), and previous works. As a main source of data a depurated earthquake catalog was collected covering the period from 1522 to 2015. This catalog was homogenized to a moment magnitude scale (Mw). After a careful analysis of all the integrated geological and seismological information, the seismogenic zones were established into seismic areas defined by similar patterns of faulting, seismicity, and rupture mechanism. The tectonic environment has required considering seismic zones in two particular seismological regimes: a) crustal faulting (including local faults, major fracture zones of plate boundary limits, and thrust fault of deformed belts) and b) subduction, taking into account the change in the subduction angle along the trench, and the type and location of the rupture. The seismicity in the subduction zone is divided into interplate and intraplate inslab seismicity. The regional seismic zonation proposed for the whole of Central America, include local seismic zonations, avoiding discontinuities at the national boundaries, because of a consensus between the 7 countries, based on the cooperative work of specialists on Central American seismotectonics and related topics.

  6. Differentiation of Enhancing Glioma and Primary Central Nervous System Lymphoma by Texture-Based Machine Learning.

    Science.gov (United States)

    Alcaide-Leon, P; Dufort, P; Geraldo, A F; Alshafai, L; Maralani, P J; Spears, J; Bharatha, A

    2017-06-01

    Accurate preoperative differentiation of primary central nervous system lymphoma and enhancing glioma is essential to avoid unnecessary neurosurgical resection in patients with primary central nervous system lymphoma. The purpose of the study was to evaluate the diagnostic performance of a machine-learning algorithm by using texture analysis of contrast-enhanced T1-weighted images for differentiation of primary central nervous system lymphoma and enhancing glioma. Seventy-one adult patients with enhancing gliomas and 35 adult patients with primary central nervous system lymphomas were included. The tumors were manually contoured on contrast-enhanced T1WI, and the resulting volumes of interest were mined for textural features and subjected to a support vector machine-based machine-learning protocol. Three readers classified the tumors independently on contrast-enhanced T1WI. Areas under the receiver operating characteristic curves were estimated for each reader and for the support vector machine classifier. A noninferiority test for diagnostic accuracy based on paired areas under the receiver operating characteristic curve was performed with a noninferiority margin of 0.15. The mean areas under the receiver operating characteristic curve were 0.877 (95% CI, 0.798-0.955) for the support vector machine classifier; 0.878 (95% CI, 0.807-0.949) for reader 1; 0.899 (95% CI, 0.833-0.966) for reader 2; and 0.845 (95% CI, 0.757-0.933) for reader 3. The mean area under the receiver operating characteristic curve of the support vector machine classifier was significantly noninferior to the mean area under the curve of reader 1 ( P = .021), reader 2 ( P = .035), and reader 3 ( P = .007). Support vector machine classification based on textural features of contrast-enhanced T1WI is noninferior to expert human evaluation in the differentiation of primary central nervous system lymphoma and enhancing glioma. © 2017 by American Journal of Neuroradiology.

  7. In vitro susceptibility and resistance phenotypes in contemporary Enterobacter isolates in a university hospital in Crete, Greece.

    Science.gov (United States)

    Maraki, Sofia; Vardakas, Konstantinos Z; Samonis, George; Perdikis, Dimitrios; Mavromanolaki, Viktoria Eirini; Kofteridis, Diamantis P; Falagas, Matthew E

    2017-06-01

    To study the evolution in the susceptibility of Enterobacter spp. in Crete, Greece from 2010 to 2015. Non-duplicate isolates were studied using automated systems. Phenotypic confirmatory tests were applied. A total of 939 Enterobacter isolates were included. Colistin was the most active antibiotic (97.9%) followed by imipenem (96.1%), gentamicin (95.7%), tigecycline (91.8%), cefepime (89.4%), chloramphenicol (85.8%), fosfomycin (85.5%), trimethoprim/sulfamethoxazole (83.3%) and piperacillin/tazobactam (73.3%). Antibiotic resistance did not increase during the study period for most antibiotics. Lower susceptibility was observed among multidrug-resistant strains and carbapenem-nonsusceptible isolates. AmpC was the most common resistant mechanism (21%); carbapenemases (3.7%) and aminoglycoside-modifying enzymes (6.5%) were also detected. A significant proportion of Enterobacter spp. was resistant to several antibiotics, most notably β-lactams.

  8. Some Phonetic Phenomena in the Central Podillia Dialect (Based on the Terminology of Traditional Folk Crafts

    Directory of Open Access Journals (Sweden)

    Kraievska Hanna

    2016-08-01

    Full Text Available Background: In the reviewed paper we attempted to investigate the phonetic variation of the Central Podillia dialect on the example of some linguistic phenomena. We found out that many linguists studied the phonetic variation based on the Ukrainians' dialect speech. However, they did not study the terminology of folk crafts of the Central Podillia dialects, that's why we aim to describe the sound differences of the lexical units of this area. Purpose: The purpose of the analysis is to determine some phonetic phenomena of the Central Podillia dialect. First of all, there are changes within the stable word length (metathesis, substantive changes of one sound in the stable surround sound, and changes, accompanied by the word elongation or contraction (prosthesis, epenthesis, elision. Results: The analyzed dialects widely present the consonant changes within the stable word length (г → ґ, т → д, с → ш, з → ж…. The performed study characterizes the Central Podillia dialects by the vowel change within a stable word length – 5 cases. Sound changes are typical for the analyzed dialects affecting the dynamics of the word length (prosthetic sounds - [г], [в], [й], [і], [и]. In opposition to the phonetic processes that help to increase the length of the word, we observe the loss of the sound in the middle of the word in the Central Podillia dialects (reduction – [o], [й], [в]. Discussion: The analysis of some phonetic phenomena of the Central Podillia dialects proved the existence of phonetic features typical for the South-Western dialect. However, we determined the local sound differences of this area, which confirm the identity of the language of this region.

  9. Lightning activity, rainfall and flash flooding – occasional or interrelated events? A case study in the island of Crete

    Directory of Open Access Journals (Sweden)

    A. G. Koutroulis

    2012-04-01

    Full Text Available The majority of cyclones passing over Crete in late autumn to early winter originate from southwest, west and northwest and are of varying size and intensity. A number of these cyclones cause flash floods. The present study reports the possible relationships between lighting activity and high precipitation related to flash flood events. In this study an attempt was made to correlate the lightning number and location, recorded by the ZEUS lightning detection system, with the rainfall characteristics for sixteen rain events (4 flood and 12 non-flood events on the island of Crete, during the period 2008–2009. Spatiotemporal analysis of rain and rain rate with flash count was performed with respect to distance (radius of flashes from raingauge location at various temporal scales, in order to examine the correlation of accumulated rainfall and lightning activity. The maximum attained statistical significant correlation was obtained within a circular area of an average radius of 15 km around the raingauge, and an average time lag of flash count prior precipitation accumulation of 15 min. The maximum correlation between the lightning and rainfall data is obtained for shorter time lags for the flood events (15 min than the non-flood events (25 min, that could reflect the faster propagation of flood triggering storms due to high convective activity. Results show increased lightning activity occurring during flood triggering storms, by an average of four times higher. Furthermore, there is evidence that the number of flashes that occur during a precipitation event is related to precipitation depth when the latter is adequate to produce a flood event. Differences between flood and non-flood producing storms need to be further assessed by analyzing more independent parameters, including the synoptic conditions and dominant flash flood hydrological generating processes.

  10. Near surface geotechnical and geophysical data cross validated for site characterization applications. The cases of selected accelerometric stations in Crete island (Greece)

    Science.gov (United States)

    Loupasakis, Constantinos; Tsangaratos, Paraskevas; Rozos, Dimitrios; Rondoyianni, Theodora; Vafidis, Antonis; Steiakakis, Emanouil; Agioutantis, Zacharias; Savvaidis, Alexandros; Soupios, Pantelis; Papadopoulos, Ioannis; Papadopoulos, Nikos; Sarris, Apostolos; Mangriotis, Maria-Dafni; Dikmen, Unal

    2015-04-01

    The near surface ground conditions are highly important for the design of civil constructions. These conditions determine primarily the ability of the foundation formations to bear loads, the stress - strain relations and the corresponding deformations, as well as the soil amplification and corresponding peak ground motion in case of dynamic loading. The static and dynamic geotechnical parameters as well as the ground-type/soil-category can be determined by combining geotechnical and geophysical methods, such as engineering geological surface mapping, geotechnical drilling, in situ and laboratory testing and geophysical investigations. The above mentioned methods were combined for the site characterization in selected sites of the Hellenic Accelerometric Network (HAN) in the area of Crete Island. The combination of the geotechnical and geophysical methods in thirteen (13) sites provided sufficient information about their limitations, setting up the minimum tests requirements in relation to the type of the geological formations. The reduced accuracy of the surface mapping in urban sites, the uncertainties introduced by the geophysical survey in sites with complex geology and the 1-D data provided by the geotechnical drills are some of the causes affecting the right order and the quantity of the necessary investigation methods. Through this study the gradual improvement on the accuracy of the site characterization data in regards to the applied investigation techniques is presented by providing characteristic examples from the total number of thirteen sites. As an example of the gradual improvement of the knowledge about the ground conditions the case of AGN1 strong motion station, located at Agios Nikolaos city (Eastern Crete), is briefly presented. According to the medium scale geological map of IGME the station was supposed to be founded over limestone. The detailed geological mapping reveled that a few meters of loose alluvial deposits occupy the area, expected

  11. Remote sensing-based characterization of rainfall during atmospheric rivers over the central United States

    Science.gov (United States)

    Nayak, Munir A.; Villarini, Gabriele

    2018-01-01

    Atmospheric rivers (ARs) play a central role in the hydrology and hydroclimatology of the central United States. More than 25% of the annual rainfall is associated with ARs over much of this region, with many large flood events tied to their occurrence. Despite the relevance of these storms for flood hydrology and water budget, the characteristics of rainfall associated with ARs over the central United has not been investigated thus far. This study fills this major scientific gap by describing the rainfall during ARs over the central United States using five remote sensing-based precipitation products over a 12-year study period. The products we consider are: Stage IV, Tropical Rainfall Measuring Mission - Multi-satellite Precipitation Analysis (TMPA, both real-time and research version); Precipitation Estimation from Remotely Sensed Information using Artificial Neural Networks (PERSIANN); the CPC MORPHing Technique (CMORPH). As part of the study, we evaluate these products against a rain gauge-based dataset using both graphical- and metrics-based diagnostics. Based on our analyses, Stage IV is found to better reproduce the reference data. Hence, we use it for the characterization of rainfall in ARs. Most of the AR-rainfall is located in a narrow region within ∼150 km on both sides of the AR major axis. In this region, rainfall has a pronounced positive relationship with the magnitude of the water vapor transport. Moreover, we have also identified a consistent increase in rainfall intensity with duration (or persistence) of AR conditions. However, there is not a strong indication of diurnal variability in AR rainfall. These results can be directly used in developing flood protection strategies during ARs. Further, weather prediction agencies can benefit from the results of this study to achieve higher skill of resolving precipitation processes in their models.

  12. Development of a Physiologically-Based Pharmacokinetic Model of the Rat Central Nervous System

    Directory of Open Access Journals (Sweden)

    Raj K. Singh Badhan

    2014-03-01

    Full Text Available Central nervous system (CNS drug disposition is dictated by a drug’s physicochemical properties and its ability to permeate physiological barriers. The blood–brain barrier (BBB, blood-cerebrospinal fluid barrier and centrally located drug transporter proteins influence drug disposition within the central nervous system. Attainment of adequate brain-to-plasma and cerebrospinal fluid-to-plasma partitioning is important in determining the efficacy of centrally acting therapeutics. We have developed a physiologically-based pharmacokinetic model of the rat CNS which incorporates brain interstitial fluid (ISF, choroidal epithelial and total cerebrospinal fluid (CSF compartments and accurately predicts CNS pharmacokinetics. The model yielded reasonable predictions of unbound brain-to-plasma partition ratio (Kpuu,brain and CSF:plasma ratio (CSF:Plasmau using a series of in vitro permeability and unbound fraction parameters. When using in vitro permeability data obtained from L-mdr1a cells to estimate rat in vivo permeability, the model successfully predicted, to within 4-fold, Kpuu,brain and CSF:Plasmau for 81.5% of compounds simulated. The model presented allows for simultaneous simulation and analysis of both brain biophase and CSF to accurately predict CNS pharmacokinetics from preclinical drug parameters routinely available during discovery and development pathways.

  13. Vaccination against human papillomavirus among 865 female students from the health professions in central Greece: a questionnaire- based cross-sectional study

    Directory of Open Access Journals (Sweden)

    Papagiannis D

    2013-11-01

    Full Text Available Dimitrios Papagiannis,1 George Rachiotis,1 Emmanouil K Symvoulakis,2 Alexandros Daponte,3 Ioanna N Grivea,4 George A Syrogiannopoulos,4 Christos Hadjichristodoulou11Department of Hygiene and Epidemiology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Thessalia, 2Private Family Practice Unit, Heraklion, Crete, 3Department of Obstetrics and Gynaecology, University of Thessalia Medical School, Thessalia, 4Department of Paediatrics, University of Thessaly, School of Medicine, General University Hospital of Larissa, Thessalia, GreeceBackground: There are still sparse data on vaccination coverage against human papillomavirus (HPV among students in the health professions. The aim of this study was to investigate HPV vaccination coverage in female students from the health professions in Greece.Methods: A self-administered, anonymous questionnaire was distributed to second-year and third-year female students pursuing degrees in medicine, nursing, and paramedical health disciplines in central Greece.Results: Overall vaccination coverage was 44.3%. The major reason for lack of vaccination was fear about safety of the vaccine. Participants who had received information about safety of the vaccine from the mass media and paramedical students had lower vaccination coverage in comparison with students who had received information about vaccine safety from alternative sources.Conclusion: Further quantitative and qualitative research is needed to design educational activities targeting female students in the health professions in order to create a positive domino effect and improve HPV vaccination coverage levels in Greece.Keywords: human papillomavirus, vaccination, coverage, students, health professions, mass media, Greece

  14. Road network selection for small-scale maps using an improved centrality-based algorithm

    Directory of Open Access Journals (Sweden)

    Roy Weiss

    2014-12-01

    Full Text Available The road network is one of the key feature classes in topographic maps and databases. In the task of deriving road networks for products at smaller scales, road network selection forms a prerequisite for all other generalization operators, and is thus a fundamental operation in the overall process of topographic map and database production. The objective of this work was to develop an algorithm for automated road network selection from a large-scale (1:10,000 to a small-scale database (1:200,000. The project was pursued in collaboration with swisstopo, the national mapping agency of Switzerland, with generic mapping requirements in mind. Preliminary experiments suggested that a selection algorithm based on betweenness centrality performed best for this purpose, yet also exposed problems. The main contribution of this paper thus consists of four extensions that address deficiencies of the basic centrality-based algorithm and lead to a significant improvement of the results. The first two extensions improve the formation of strokes concatenating the road segments, which is crucial since strokes provide the foundation upon which the network centrality measure is computed. Thus, the first extension ensures that roundabouts are detected and collapsed, thus avoiding interruptions of strokes by roundabouts, while the second introduces additional semantics in the process of stroke formation, allowing longer and more plausible strokes to built. The third extension detects areas of high road density (i.e., urban areas using density-based clustering and then locally increases the threshold of the centrality measure used to select road segments, such that more thinning takes place in those areas. Finally, since the basic algorithm tends to create dead-ends—which however are not tolerated in small-scale maps—the fourth extension reconnects these dead-ends to the main network, searching for the best path in the main heading of the dead-end.

  15. The efficacy of centralized flow rate control in 802.11-based wireless mesh networks

    KAUST Repository

    Jamshaid, K.

    2013-06-13

    Commodity WiFi-based wireless mesh networks (WMNs) can be used to provide last mile Internet access. These networks exhibit extreme unfairness with backlogged traffic sources. Current solutions propose distributed source-rate control algorithms requiring link-layer or transport-layer changes on all mesh nodes. This is often infeasible in large practical deployments. In wireline networks, router-assisted rate control techniques have been proposed for use alongside end-to-end mechanisms. We wish to evaluate the feasibility of establishing similar centralized control via gateways in WMNs. In this paper, we focus on the efficacy of this control rather than the specifics of the controller design mechanism. We answer the question: Given sources that react predictably to congestion notification, can we enforce a desired rate allocation through a single centralized controller? The answer is not obvious because flows experience varying contention levels, and transmissions are scheduled by a node using imperfect local knowledge. We find that common router-assisted flow control schemes used in wired networks fail in WMNs because they assume that (1) links are independent, and (2) router queue buildups are sufficient for detecting congestion. We show that non-work-conserving, rate-based centralized scheduling can effectively enforce rate allocation. It can achieve results comparable to source rate limiting, without requiring any modifications to mesh routers or client devices. 2013 Jamshaid et al.; licensee Springer.

  16. Low prevalence of liver-kidney microsomal autoantibodies of type 1 (LKM1 in hepatitis C seropositive subjects on Crete, Greece

    Directory of Open Access Journals (Sweden)

    Pappas Georgios

    2001-06-01

    Full Text Available Abstract Background Hepatitis C is a serious problem on the Greek island of Crete, where a high prevalence of antibodies against hepatitis C (anti-HCV has recently been reported. This article reports the findings of a study carried out in Crete, which investigated the prevalence of serum autoantibodies in patients with chronic hepatitis C. Patients and Methods One hundred and forty two patients (59 men and 83 women, who were found anti-HCV seropositive in two hospitals and two Primary Health Care Centres in Crete, were eligible. Sixty healthy blood donors (46 men, 14 women, which were negative to anti-HCV, were used as the control group. They were randomly selected from those attending Rethymnon Hospital. Autoantibodies were identified using the indirect immunofluorescence (IFL technique on human epithelial cells from larynx cancer (HEp-2 cells, rat liver-kidney-stomach substrate (CT3 and Chrithidia Luciliae (CL. Results Serum autoantibodies were detected in 104 HCV patients, yielding an overall prevalence of 73.2%. The most frequent autoantibodies were antinuclear antibodies (ANA, positive in 72 patients (50.7%. Anti-smooth muscle antibodies (ASMA were detected in 33 patients (23.2%. Only one patient was positive for LKM1 autoantibodies. No autoantibodies were found in 38 patients (26.7%. Autoantibodies were also found in 5 out of the 60 examined healthy blood donors (8.3%. Conclusions Autoantibodies, mainly ANA and ASMA are very common in HCV seropositive patients from Crete. By contrast LKM1 autoantibodies are exceptionally rare in these patients.

  17. Surgical treatment for central pain after stroke based on the neural mechanism

    International Nuclear Information System (INIS)

    Hirato, Masafumi; Takahashi, Akio; Watanabe, Katsushige; Kazama, Ken; Yoshimoto, Yuhei

    2008-01-01

    Previous neurophysiological and neuroimaging studies have suggested that functional changes might occur in the sensory thalamus, associated with reorganization of the thalamocortical system, in cases with central pain after stroke (thalamic pain). It might cause the misconduction of the sensory signal or a hyperactive response to peripheral natural stimulation on the thalamus, resulting in it playing an important roles in the genesis of central pain. Hyperactivity in the cerebral cortex adjacent to the central sulcus on the side ipsilateral to a cerebrovascular disease (CVD) lesion also might relate to central pain. We performed various kinds of surgical treatments in 29 cases with central pain after stroke based on the neural mechanism deserbed above. Epidural spinal cord stimulation was effective in 4 out of 7 cases with localized pain on the distal part of the leg and arm. We achieved pain control in these cases showing definite somatosensory evoked potential (SEP) originating in the sensory cortex before surgery. Stereotactic (Vim-Vcpc) thalamotomy with the aid of depth microrecording was effective in 4 out of 7 cases with diffuse pain. In good responders, we could find responses to natural peripheral stimulation and seldom encountered irregular burst discharges in the sensory thalamus during the operation. Preoperative positron emission tomography (PET) studies also revealed an increase of regional cerebral blood flow (rCBF) in the sensory cortex ipsilateral to the thalamic CVD lesion during contralateral thumb brushing. Gamma knife treatment was effective in 5 out of 7 cases after stereotactic thalamotomy. It became stable in 3 out of these 5 cases. Each case was treated with a maximum dose of 120-150 Gy using a 4 mm collimator. Precentral electrical cortical stimulation was performed in 8 cases. Sufficient pain relief was achieved in 3 out of 6 cases in which we could implant an importable pulse generator (IPG). In one of these cases, we found definite

  18. [Maxillary swing approach in the management of tumors in the central and lateral cranial base].

    Science.gov (United States)

    Liao, Hua; Hua, Qing-quan; Wu, Zhan-yuan

    2006-04-01

    A retrospective review of seventeen patients who were operated through the maxillary swing approach was carried out to assess the efficacy of this approach in the management of tumors of the central and lateral cranial base. From May 2000 to January 2005, 17 patients with primary or recurrent neoplasms involving the central cranial or lateral base underwent surgical resection via maxillary swing approach. Ten patients were male, and other seven patients were female, and age range was 7 to 58 years, with a mean age of 42. 6 years. Eight patients had tumors originally involving lateral cranial base, and nine patients had tumors originated from central cranial base. The pathology spectrum was very wide. Among them, five suffered from chordoma, two had rhabdomyosarcoma, two had squamous cell carcinoma, one had malignant fibrous histiocytoma, one had malignant melanoma, one had esthesioneuroblastoma, one had invaded hypophysoma, two had schwannoma, one had pleomorphic adenoma, and one had angiofibroma. Three patients had received previous surgery, two patients had previous radiation therapy and nine patients received postoperative radiotherapy. Sixteen of all seventeen patients had oncologically complete resection, one had near-total resection. This group patients was followed up from 10 to 60 months, with a median follow-up time of 28 months. Two patients died 14 and 26 months after surgery respectively, as a result of local recurrence and metastasis. One patient defaulted follow-up at 12 months after operation, and the other 14 patients were alive at the time of analysis. Of the 12 malignant tumors, the 1-and 2-year survival rate were 91.67% and 72.92%, respectively. The facial wounds of all patients healed primarily, and there were no necrosis of the maxilla, damage of the temporal branch of the facial nerve, lower-lid ectropion, and facial deformity. Epiphora and facial hypoesthesia were detected in all patients. Four patients (23.5%) developed palatal fistula, ten

  19. Assessment of age based on the pulp cavity width of the maxillary central incisors

    Directory of Open Access Journals (Sweden)

    Uday Ginjupally

    2014-01-01

    Full Text Available Aims and Objectives: The aim of this study was to estimate the age of the patients belonging to the age group of 15 - 55 years, attending the Department of Oral Medicine and Radiology, St. Joseph Dental College and Hospital, Eluru, based on the radiographic evaluation of the pulp cavity width of the maxillary central incisors. Materials and Methods: The study group comprised of 120 subjects. Intraoral periapical radiographs of the maxillary central incisors were taken for all subjects, using the conventional paralleling angle technique and the pulp cavity width was measured at the cervical and middle third using a digital vernier caliper. The data obtained was subjected to correlation and regression analysis. Results: A negative linear relationship was obtained between the age and pulp cavity width (cervical third, r = -0.459 and middle third, r = -0.704. Cubic regression analysis was done and the regression formulae were obtained. A mean difference of 0.1 years was obtained between the estimated age and real age, indicating the reliability of the derived formula. Conclusion: It can be concluded that the width of the pulp cavity of maxillary central incisors are reliable for estimation of age.

  20. Electric protections based in microprocessors in power plants; Protecciones electricas basadas en microprocesadores en centrales generadoras

    Energy Technology Data Exchange (ETDEWEB)

    Libreros, Domitilo; Castanon Jimenez, Jose Ismael [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1988-12-31

    This article is centered around the substitution of the conventional electric protections of a power plant in connection type unit for protections based in microprocessors. A general model of conventional protection of a power plant is described and the number of analogic and digital signals that intervene in that model are quantified. A model is setup for power plant protection with microprocessors, analyzing each one of the modules that would form it. Finally, the algorithms to carry on such protection are presented. [Espanol] Este articulo se centra en torno a la sustitucion de las protecciones electricas convencionales de una central generadora en conexion tipo unidad por protecciones basadas en microprocesadores. Se describe el modelo general de proteccion convencional de una central generadora y se cuantifica el numero de senales analogicas y digitales que interviene en dicho modelo. Se propone un modelo para proteccion de centrales generadoras mediante microprocesadores, analizandose cada uno de los modulos que lo conformarian. Finalmente, se presentan los algoritmos para realizar dicha proteccion.

  1. Electric protections based in microprocessors in power plants; Protecciones electricas basadas en microprocesadores en centrales generadoras

    Energy Technology Data Exchange (ETDEWEB)

    Libreros, Domitilo; Castanon Jimenez, Jose Ismael [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1987-12-31

    This article is centered around the substitution of the conventional electric protections of a power plant in connection type unit for protections based in microprocessors. A general model of conventional protection of a power plant is described and the number of analogic and digital signals that intervene in that model are quantified. A model is setup for power plant protection with microprocessors, analyzing each one of the modules that would form it. Finally, the algorithms to carry on such protection are presented. [Espanol] Este articulo se centra en torno a la sustitucion de las protecciones electricas convencionales de una central generadora en conexion tipo unidad por protecciones basadas en microprocesadores. Se describe el modelo general de proteccion convencional de una central generadora y se cuantifica el numero de senales analogicas y digitales que interviene en dicho modelo. Se propone un modelo para proteccion de centrales generadoras mediante microprocesadores, analizandose cada uno de los modulos que lo conformarian. Finalmente, se presentan los algoritmos para realizar dicha proteccion.

  2. Archiving and retrieval of experimental data using SAN based centralized storage system for SST-1

    Energy Technology Data Exchange (ETDEWEB)

    Bhandarkar, Manisha, E-mail: manisha@ipr.res.in; Masand, Harish; Kumar, Aveg; Patel, Kirit; Dhongde, Jasraj; Gulati, Hitesh; Mahajan, Kirti; Chudasama, Hitesh; Pradhan, Subrata

    2016-11-15

    Highlights: • SAN (Storage Area Network) based centralized data storage system of SST-1 has envisaged to address the need of centrally availability of SST-1 storage system to archive/retrieve experimental data for the authenticated users for 24 × 7. • The SAN based data storage system has been designed/configured with 3-tiered architecture and GFS cluster file system with multipath support. • The adopted SAN based data storage for SST-1 is a modular, robust, and allows future expandability. • Important considerations has been taken like, Handling of varied Data writing speed from different subsystems to central storage, Simultaneous read access of the bulk experimental and as well as essential diagnostic data, The life expectancy of data, How often data will be retrieved and how fast it will be needed, How much historical data should be maintained at storage. - Abstract: SAN (Storage Area Network, a high-speed, block level storage device) based centralized data storage system of SST-1 (Steady State superconducting Tokamak) has envisaged to address the need of availability of SST-1 operation & experimental data centrally for archival as well as retrieval [2]. Considering the initial data volume requirement, ∼10 TB (Terabytes) capacity of SAN based data storage system has configured/installed with optical fiber backbone with compatibility considerations of existing Ethernet network of SST-1. The SAN based data storage system has been designed/configured with 3-tiered architecture and GFS (Global File System) cluster file system with multipath support. Tier-1 is of ∼3 TB (frequent access and low data storage capacity) comprises of Fiber channel (FC) based hard disks for optimum throughput. Tier-2 is of ∼6 TB (less frequent access and high data storage capacity) comprises of SATA based hard disks. Tier-3 will be planned later to store offline historical data. In the SAN configuration two tightly coupled storage servers (with cluster configuration) are

  3. Archiving and retrieval of experimental data using SAN based centralized storage system for SST-1

    International Nuclear Information System (INIS)

    Bhandarkar, Manisha; Masand, Harish; Kumar, Aveg; Patel, Kirit; Dhongde, Jasraj; Gulati, Hitesh; Mahajan, Kirti; Chudasama, Hitesh; Pradhan, Subrata

    2016-01-01

    Highlights: • SAN (Storage Area Network) based centralized data storage system of SST-1 has envisaged to address the need of centrally availability of SST-1 storage system to archive/retrieve experimental data for the authenticated users for 24 × 7. • The SAN based data storage system has been designed/configured with 3-tiered architecture and GFS cluster file system with multipath support. • The adopted SAN based data storage for SST-1 is a modular, robust, and allows future expandability. • Important considerations has been taken like, Handling of varied Data writing speed from different subsystems to central storage, Simultaneous read access of the bulk experimental and as well as essential diagnostic data, The life expectancy of data, How often data will be retrieved and how fast it will be needed, How much historical data should be maintained at storage. - Abstract: SAN (Storage Area Network, a high-speed, block level storage device) based centralized data storage system of SST-1 (Steady State superconducting Tokamak) has envisaged to address the need of availability of SST-1 operation & experimental data centrally for archival as well as retrieval [2]. Considering the initial data volume requirement, ∼10 TB (Terabytes) capacity of SAN based data storage system has configured/installed with optical fiber backbone with compatibility considerations of existing Ethernet network of SST-1. The SAN based data storage system has been designed/configured with 3-tiered architecture and GFS (Global File System) cluster file system with multipath support. Tier-1 is of ∼3 TB (frequent access and low data storage capacity) comprises of Fiber channel (FC) based hard disks for optimum throughput. Tier-2 is of ∼6 TB (less frequent access and high data storage capacity) comprises of SATA based hard disks. Tier-3 will be planned later to store offline historical data. In the SAN configuration two tightly coupled storage servers (with cluster configuration) are

  4. Palaeocology of coal-bearing Eocene sediments in central Anatolia (Turkey) based on quantitative palynological data

    Energy Technology Data Exchange (ETDEWEB)

    Akkiraz, M.S.; Kayseri, M.S.; Akgun, F. [Dokuz Eylul University, Izmir (Turkey). Dept. of Geological Engineering

    2008-04-15

    In this study, the lignite-bearing Yoncali formation between Yozgat and Sorgun, in central Anatolia has been palynologically examined. Based on 37 outcrop samples, quantitative palynological studies recognized 64 genera and 136 palynoflora species in the palynological assemblage, which indicated a Middle-Late Eocene age. This paper also presents a quantitative palaeovegetation and palaeoclimate reconstruction for the Middle-Upper Eocene coal occurrences of Central Anatolia on the basis of palynomorph assemblages. The diversified floral and ecological characteristics of the pollen taxa indicates that the Middle-Upper Eocene formations in central Anatolia were characterized by the presence of a complex mangrove swamp with contributions by Nypa, Pelliciera, Avicennia, Diporites tszkaszentgydrgyi and dinoflagellate cysts which reflect warm climatic conditions. Lowland-riparian and montane elements are characterized by the dominance of Myricaceae, Symplocaceae, Icacinaceae, Quercus, Pinus and Castanea. Swamp-freshwater elements are represented by Sparganjaceae, Nymphaceae, Taxodjaceae, Cupressaceae and Nyssa as well as fern spores such as Osmundaceae and Gleicheniaceae. The calculations were performed with the help of the 'Coexistence Approach' method to climatically evaluate palynoflora from the Yozgat-Sorgun area. The obtained results have been compared to data derived from the application of the Coexistence Approach to other, already published Central Anatolian palynofloras of the same age. The results of the climatic inferences suggest that the palaeoclimatic conditions were in the megathermal zone, megatherm/mesotherm intermediate zone whereas mesothermic conditions prevailed in the montane region. Likewise, the results of mean annual range of temperatures indicate the influence of the Indian ocean, which enabled the development of the mangroves.

  5. Modeling infection transmission in primate networks to predict centrality-based risk.

    Science.gov (United States)

    Romano, Valéria; Duboscq, Julie; Sarabian, Cécile; Thomas, Elodie; Sueur, Cédric; MacIntosh, Andrew J J

    2016-07-01

    Social structure can theoretically regulate disease risk by mediating exposure to pathogens via social proximity and contact. Investigating the role of central individuals within a network may help predict infectious agent transmission as well as implement disease control strategies, but little is known about such dynamics in real primate networks. We combined social network analysis and a modeling approach to better understand transmission of a theoretical infectious agent in wild Japanese macaques, highly social animals which form extended but highly differentiated social networks. We collected focal data from adult females living on the islands of Koshima and Yakushima, Japan. Individual identities as well as grooming networks were included in a Markov graph-based simulation. In this model, the probability that an individual will transmit an infectious agent depends on the strength of its relationships with other group members. Similarly, its probability of being infected depends on its relationships with already infected group members. We correlated: (i) the percentage of subjects infected during a latency-constrained epidemic; (ii) the mean latency to complete transmission; (iii) the probability that an individual is infected first among all group members; and (iv) each individual's mean rank in the chain of transmission with different individual network centralities (eigenvector, strength, betweenness). Our results support the hypothesis that more central individuals transmit infections in a shorter amount of time and to more subjects but also become infected more quickly than less central individuals. However, we also observed that the spread of infectious agents on the Yakushima network did not always differ from expectations of spread on random networks. Generalizations about the importance of observed social networks in pathogen flow should thus be made with caution, since individual characteristics in some real world networks appear less relevant than

  6. SOTER-based soil parameter estimates for Central Africa - DR of Congo, Burundi and Rwanda (ver. 1.0)

    NARCIS (Netherlands)

    Batjes, N.H.

    2014-01-01

    This harmonized set of soil parameter estimates for Central Africa, comprising Burundi, the Democratic Republic of the Congo and Rwanda, was derived from the Soil and Terrain Database for Central Africa (SOTERCAF ver. 1.0) and the ISRIC-WISE soil profile database, using standardized taxonomy-based

  7. Central tracker for BM@N experiment based on double side Si-microstrip detectors

    Science.gov (United States)

    Kovalev, Yu.; Kapishin, M.; Khabarov, S.; Shafronovskaia, A.; Tarasov, O.; Makankin, A.; Zamiatin, N.; Zubarev, E.

    2017-07-01

    Design of central tracker system based on Double-Sided Silicon Detectors (DSSD) for BM@N experiment is described. A coordinate plane with 10240 measuring channels, pitch adapter, reading electronics was developed. Each element was tested and assembled into a coordinate plane. The first tests of the plane with 106Ru source were carried out before installation for the BM@N experiment. The results of the study indicate that noisy channels and inefficient channels are less than 3%. In general, single clusters 87% (one group per module of consecutive strips) and 75% of clusters with a width equal to one strip.

  8. Prototype Centralized Managing Permissions System Based on the Election Multibiometric Authentication

    Directory of Open Access Journals (Sweden)

    Alexey Nikolaevich Ruchay

    2013-02-01

    Full Text Available This work aims to develop a prototype system of centralized managing permissions based on the election multibiometric authentication. The novelty of this work is to develop the principles of distinction and multi-factor authentication, because at the moment there is no such development. Depending on various conditions and factors, including the availability of electronic means and convenience, resistance to attacks and exploits, disease or injury of users the biometric authentication can be selected on the basis of any such biometrics as rhythm password, voice, dynamic signatures and graphics recognition.

  9. Structural analysis of the central Columbia Plateau utilizing radar, digital topography, and magnetic data bases

    International Nuclear Information System (INIS)

    Thiessen, R.L.; Eliason, J.R.; Johnson, L.K.; Brougher, C.W.

    1991-08-01

    Interest in the Hanford site (Washington) as a nuclear production, power, and waste disposal site has led to generation of a vast quantity of geophysical and remote sensing data sets of the central Columbia Plateau. To data, these various studies, including at least 13 independent magnetic linear and image lineament studies, have not been adequately correlated. Therefore, these studies provide a unique opportunity to compare and contrast the viability of the different geophysical and remote sensing techniques. The geology of the central Columbia Plateau is characterized by subdued topography and limited outcrop, with most of the exposure concentrated in localized folded/faulted mountains (the Yakima folds) and along river canyons. In order to efficiently compare lineament data bases, we have written an automated computer routine that correlated lineaments that are within a user specified distance of each other. The angle between their trends has to be less than an input maximum separation angle. If more than two lineament maps exist for the area, the analyst may also specify the minimum number of times each structure must be seen. The lineament correlation routine was applied to data bases of all aeromagnetic linears as well as lineaments seen on radar and a digital elevation model DEM image. Geologic structures align with a set of three-dimensional planar structures identified with our Geologic Spatial Analysis (GSA) system. The GSA analysis is based upon computer automated detection of valley bottoms as defined by a DEM

  10. Central FPGA-based destination and load control in the LHCb MHz event readout

    Science.gov (United States)

    Jacobsson, R.

    2012-10-01

    The readout strategy of the LHCb experiment is based on complete event readout at 1 MHz. A set of 320 sub-detector readout boards transmit event fragments at total rate of 24.6 MHz at a bandwidth usage of up to 70 GB/s over a commercial switching network based on Gigabit Ethernet to a distributed event building and high-level trigger processing farm with 1470 individual multi-core computer nodes. In the original specifications, the readout was based on a pure push protocol. This paper describes the proposal, implementation, and experience of a non-conventional mixture of a push and a pull protocol, akin to credit-based flow control. An FPGA-based central master module, partly operating at the LHC bunch clock frequency of 40.08 MHz and partly at a double clock speed, is in charge of the entire trigger and readout control from the front-end electronics up to the high-level trigger farm. One FPGA is dedicated to controlling the event fragment packing in the readout boards, the assignment of the farm node destination for each event, and controls the farm load based on an asynchronous pull mechanism from each farm node. This dynamic readout scheme relies on generic event requests and the concept of node credit allowing load control and trigger rate regulation as a function of the global farm load. It also allows the vital task of fast central monitoring and automatic recovery in-flight of failing nodes while maintaining dead-time and event loss at a minimum. This paper demonstrates the strength and suitability of implementing this real-time task for a very large distributed system in an FPGA where no random delays are introduced, and where extreme reliability and accurate event accounting are fundamental requirements. It was in use during the entire commissioning phase of LHCb and has been in faultless operation during the first two years of physics luminosity data taking.

  11. Central FPGA-based destination and load control in the LHCb MHz event readout

    International Nuclear Information System (INIS)

    Jacobsson, R.

    2012-01-01

    The readout strategy of the LHCb experiment is based on complete event readout at 1 MHz. A set of 320 sub-detector readout boards transmit event fragments at total rate of 24.6 MHz at a bandwidth usage of up to 70 GB/s over a commercial switching network based on Gigabit Ethernet to a distributed event building and high-level trigger processing farm with 1470 individual multi-core computer nodes. In the original specifications, the readout was based on a pure push protocol. This paper describes the proposal, implementation, and experience of a non-conventional mixture of a push and a pull protocol, akin to credit-based flow control. An FPGA-based central master module, partly operating at the LHC bunch clock frequency of 40.08 MHz and partly at a double clock speed, is in charge of the entire trigger and readout control from the front-end electronics up to the high-level trigger farm. One FPGA is dedicated to controlling the event fragment packing in the readout boards, the assignment of the farm node destination for each event, and controls the farm load based on an asynchronous pull mechanism from each farm node. This dynamic readout scheme relies on generic event requests and the concept of node credit allowing load control and trigger rate regulation as a function of the global farm load. It also allows the vital task of fast central monitoring and automatic recovery in-flight of failing nodes while maintaining dead-time and event loss at a minimum. This paper demonstrates the strength and suitability of implementing this real-time task for a very large distributed system in an FPGA where no random delays are introduced, and where extreme reliability and accurate event accounting are fundamental requirements. It was in use during the entire commissioning phase of LHCb and has been in faultless operation during the first two years of physics luminosity data taking.

  12. The Central Simulation Committee (CSC): a model for centralization and standardization of simulation-based medical education in the U.S. Army healthcare system.

    Science.gov (United States)

    Deering, Shad; Sawyer, Taylor; Mikita, Jeffrey; Maurer, Douglas; Roth, Bernard J

    2012-07-01

    In this report, we describe the organizational framework, operations and current status of the Central Simulation Committee (CSC). The CSC was established in 2007 with the goals of standardizing simulation-based training in Army graduate medical education programs, assisting in redeployment training of physicians returning from war, and improving patient safety within the Army Medical Department. Presently, the CSC oversees 10 Simulation Centers, controls over 21,000 sq ft of simulation center space, and provides specialty-specific training in 14 medical specialties. In the past 2 years, CSC Simulation Centers have trained over 50,000 Army medical students, residents, physician assistants, nurses, Soldiers and DoD civilian medical personnel. We hope this report provides simulation educators within the military, and our civilian simulation colleagues, with insight into the workings of our organization and provides an example of centralized support and oversight of simulation-based medical education.

  13. An application-layer based centralized information access control for VPN

    Institute of Scientific and Technical Information of China (English)

    OUYANG Kai; ZHOU Jing-li; XIA Tao; YU Sheng-sheng

    2006-01-01

    With the rapid development of Virtual Private Network (VPN), many companies and organizations use VPN to implement their private communication. Traditionally, VPN uses security protocols to protect the confidentiality of data, the message integrity and the endpoint authentication. One core technique of VPN is tunneling, by which clients can access the internal servers traversing VPN. However, the tunneling technique also introduces a concealed security hole. It is possible that ifone vicious user can establish tunneling by the VPN server, he can compromise the internal servers behind the VPN server. So this paper presents a novel Application-layer based Centralized Information Access Control (ACIAC) for VPN to solve this problem.To implement an efficient, flexible and multi-decision access control model, we present two key techniques to ACIAC-the centralized management mechanism and the stream-based access control. Firstly, we implement the information center and the constraints/events center for ACIAC. By the two centers, we can provide an abstract access control mechanism, and the material access control can be decided dynamically by the ACIAC's constraint/event mechanism. Then we logically classify the VPN communication traffic into the access stream and the data stream so that we can tightly couple the features of VPN communication with the access control model. We also provide the design of our ACIAC prototype in this paper.

  14. A PEG Construction of LDPC Codes Based on the Betweenness Centrality Metric

    Directory of Open Access Journals (Sweden)

    BHURTAH-SEEWOOSUNGKUR, I.

    2016-05-01

    Full Text Available Progressive Edge Growth (PEG constructions are usually based on optimizing the distance metric by using various methods. In this work however, the distance metric is replaced by a different one, namely the betweenness centrality metric, which was shown to enhance routing performance in wireless mesh networks. A new type of PEG construction for Low-Density Parity-Check (LDPC codes is introduced based on the betweenness centrality metric borrowed from social networks terminology given that the bipartite graph describing the LDPC is analogous to a network of nodes. The algorithm is very efficient in filling edges on the bipartite graph by adding its connections in an edge-by-edge manner. The smallest graph size the new code could construct surpasses those obtained from a modified PEG algorithm - the RandPEG algorithm. To the best of the authors' knowledge, this paper produces the best regular LDPC column-weight two graphs. In addition, the technique proves to be competitive in terms of error-correcting performance. When compared to MacKay, PEG and other recent modified-PEG codes, the algorithm gives better performance over high SNR due to its particular edge and local graph properties.

  15. A Combination of Central Pattern Generator-based and Reflex-based Neural Networks for Dynamic, Adaptive, Robust Bipedal Locomotion

    DEFF Research Database (Denmark)

    Di Canio, Giuliano; Larsen, Jørgen Christian; Wörgötter, Florentin

    2016-01-01

    Robotic systems inspired from humans have always been lightening up the curiosity of engineers and scientists. Of many challenges, human locomotion is a very difficult one where a number of different systems needs to interact in order to generate a correct and balanced pattern. To simulate...... the interaction of these systems, implementations with reflexbased or central pattern generator (CPG)-based controllers have been tested on bipedal robot systems. In this paper we will combine the two controller types, into a controller that works with both reflex and CPG signals. We use a reflex-based neural...... network to generate basic walking patterns of a dynamic bipedal walking robot (DACBOT) and then a CPG-based neural network to ensure robust walking behavior...

  16. A Centralized Detection of Sinkhole Attacks Based on Energy Level of the Nodes on Cluster-Based Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Merve Nilay Aydın

    2017-10-01

    Full Text Available Wireless Sensor Networks is consist of thousands of small and low-cost devices, which communicate over wireless medium. Due to locating in harsh environment and having limited resources, WSN is prone to various attacks. One of the most dangerous attacks threatening WSN is the sinkhole attack. In this paper, sinkhole attack is modelled on a cluster-based WSN, and a centralized detection algorithm based on the remaining energies of the nodes is proposed. The simulations were run for different values of energy thresholds and various numbers of nodes. The performance of the system was investigated over total energy consumption in the system, the number of packets arrived at base station and true detection rate of the sinkhole node(s. The results showed that the proposed method is energy-efficient and detects the malicious nodes with a 100% accuracy for all number of nodes.

  17. NPP-VIIRS DNB-based reallocating subpopulations to mercury in Urumqi city cluster, central Asia

    Science.gov (United States)

    Zhou, X.; Feng, X. B.; Dai, W.; Li, P.; Ju, C. Y.; Bao, Z. D.; Han, Y. L.

    2017-02-01

    Accurate and update assignment of population-related environmental matters onto fine grid cells in oasis cities of arid areas remains challenging. We present the approach based on Suomi National Polar-orbiting Partnership (S-NPP) -Visible Infrared Imaging Radiometer Suite (VIIRS) Day/Night Band (DNB) to reallocate population onto a regular finer surface. The number of potential population to the mercury were reallocated onto 0.1x0.1 km reference grid in Urumqi city cluster of China’s Xinjiang, central Asia. The result of Monte Carlo modelling indicated that the range of 0.5 to 2.4 million people was reliable. The study highlights that the NPP-VIIRS DNB-based multi-layered, dasymetric, spatial method enhances our abilities to remotely estimate the distribution and size of target population at the street-level scale and has the potential to transform control strategies for epidemiology, public policy and other socioeconomic fields.

  18. Mobile devices for community-based REDD+ monitoring: a case study for Central Vietnam.

    Science.gov (United States)

    Pratihast, Arun Kumar; Herold, Martin; Avitabile, Valerio; de Bruin, Sytze; Bartholomeus, Harm; Souza, Carlos M; Ribbe, Lars

    2012-12-20

    Monitoring tropical deforestation and forest degradation is one of the central elements for the Reduced Emissions from Deforestation and Forest Degradation in developing countries (REDD+) scheme. Current arrangements for monitoring are based on remote sensing and field measurements. Since monitoring is the periodic process of assessing forest stands properties with respect to reference data, adopting the current REDD+ requirements for implementing monitoring at national levels is a challenging task. Recently, the advancement in Information and Communications Technologies (ICT) and mobile devices has enabled local communities to monitor their forest in a basic resource setting such as no or slow internet connection link, limited power supply, etc. Despite the potential, the use of mobile device system for community based monitoring (CBM) is still exceptional and faces implementation challenges. This paper presents an integrated data collection system based on mobile devices that streamlines the community-based forest monitoring data collection, transmission and visualization process. This paper also assesses the accuracy and reliability of CBM data and proposes a way to fit them into national REDD+ Monitoring, Reporting and Verification (MRV) scheme. The system performance is evaluated at Tra Bui commune, Quang Nam province, Central Vietnam, where forest carbon and change activities were tracked. The results show that the local community is able to provide data with accuracy comparable to expert measurements (index of agreement greater than 0.88), but against lower costs. Furthermore, the results confirm that communities are more effective to monitor small scale forest degradation due to subsistence fuel wood collection and selective logging, than high resolution remote sensing SPOT imagery.

  19. A household survey on the extent of home medication storage. A cross-sectional study from rural Crete, Greece.

    Science.gov (United States)

    Tsiligianni, Ioanna G; Delgatty, Candida; Alegakis, Athanasios; Lionis, Christos

    2012-03-01

    Patients often have multiple chronic diseases, use multiple prescriptions and over the counter medications resulting in polypharmacy. Many of them store these medications for future use in their homes, rather than take them as directed by their physician, resulting in a waste of health care resources, and potentially dangerous misuse. This study aimed to investigate the magnitude of medication home hoarding, the exchange of medication with family/friends, families' beliefs about the medication use, source of medication, pharmaceutical class, cost of stored medicine and conditions of storage. A structured questionnaire was administered within the homes in two rural areas in Crete. Forty families participated in the study including 85 individual household members (36 men, and 49 women with an average age of 56.5 ± 24.3 mean ± SD). There were a total of 557 medications recorded, with 324 different medications representing a total value of €8954. The mean quantity of medication boxes stored in each home was 8.5 ± 5.8. Cardiovascular medications accounted for 56% of medications for current use; whereas analgesics (24%), and antibiotics (17%), were the most medications being stored for future use. Exchange of medicine was very common (95%). Beliefs that 'more expensive medication is more effective', and that 'over the counter medications are safe because they were easily available' were expressed. Medications are being stored in large quantities in these rural areas, with a large percentage of them being wasted or misused.

  20. Incorporating Open/Free GIS and GPS Software in Power Transmission Line Routine Work: The Case of Crete and Rhodes

    Directory of Open Access Journals (Sweden)

    D. Pylarinos

    2017-02-01

    Full Text Available Geographical Information System (GIS and Global Positioning System (GPS software are widely gaining attention in power system planning and operation. Although commercial systems are increasingly being incorporated in power systems applications, they are yet to be fully incorporated in the routine work of utilities (and especially in the work of crews, due to several reasons such as cost, portability, connectivity, performance/speed, infrastructure etc. This paper focuses on incorporating certain open/free GIS and GPS software in routine transmission line work. The case study is the 150kV transmission systems of the Greek islands of Crete and Rhodes which show increased complexity due to certain localized factors such as Greek legislation, the diverse terrain/routes, the segmented design due to the network’s growth over the years (regarding both voltage levels and routes and the use of different Coordinate Reference Systems (or Geodetic Systems from the Greek state. The main goals of this work was to incorporate open/free software that provided limitless online access points, offline navigation and a user friendly design that wouldn’t require any additional training, programming etc. The basic scheme described in this paper can be followed to provide similar results in other applications.

  1. Evidence of Hierarchy in the Complex Fractured System of Geropotamos (Crete, Greece), as Extracted from Transient Electromagnetic Responses

    Science.gov (United States)

    Vallianatos, Filippos; Kouli, Maria; Kalisperi, Despina

    2018-03-01

    The essential goals of this paper are to test the transient electromagnetic (TEM) response in a fractured geological complex medium and to better understand the physics introduced by associating a roughness parameter β to the geological formation. An anomalous fractional diffusion approach is incorporated to describe the electromagnetic induction in rough multi-scaled geological structures. The multi-scaling characteristics of Geropotamos basin in Crete are revealed through the analysis of transient step-off response of an EM loop antenna. The semi-empirical parameters derived from late-time TEM measurements are correlated with the multi-scale heterogeneities of the medium. Certain interesting properties of the late-time slope γ(β) and the power law of near surface resistivity distribution, as extracted from TEM inversion for different depth, are presented. The analysis of the parameter γ(β) which scales the induced voltage in the loop in the late stage of the electromagnetic response leads to a different view of the EM geophysical data interpretation. We show that it is strongly correlated with areas of high fracture density within the geological formations of the Geropotamos area. For that reason, it is proposed as a local multi-scaling empirical index. The results of this paper suggest that anomalous diffusion could be a viable physical mechanism for the fractal transport of charge carriers, explaining observed late-time TEM responses across a variety of natural geological settings.

  2. CENTERA: A Centralized Trust-Based Efficient Routing Protocol with Authentication for Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Ayman Tajeddine

    2015-02-01

    Full Text Available In this paper, we present CENTERA, a CENtralized Trust-based Efficient Routing protocol with an appropriate authentication scheme for wireless sensor networks (WSN. CENTERA utilizes the more powerful base station (BS to gather minimal neighbor trust information from nodes and calculate the best routes after isolating different types of “bad” nodes. By periodically accumulating these simple local observations and approximating the nodes’ battery lives, the BS draws a global view of the network, calculates three quality metrics—maliciousness, cooperation, and compatibility—and evaluates the Data Trust and Forwarding Trust values of each node. Based on these metrics, the BS isolates “bad”, “misbehaving” or malicious nodes for a certain period, and put some nodes on probation. CENTERA increases the node’s bad/probation level with repeated “bad” behavior, and decreases it otherwise. Then it uses a very efficient method to distribute the routing information to “good” nodes. Based on its target environment, and if required, CENTERA uses an authentication scheme suitable for severely constrained nodes, ranging from the symmetric RC5 for safe environments under close administration, to pairing-based cryptography (PBC for hostile environments with a strong attacker model. We simulate CENTERA using TOSSIM and verify its correctness and show some energy calculations.

  3. CENTERA: A Centralized Trust-Based Efficient Routing Protocol with Authentication for Wireless Sensor Networks †

    Science.gov (United States)

    Tajeddine, Ayman; Kayssi, Ayman; Chehab, Ali; Elhajj, Imad; Itani, Wassim

    2015-01-01

    In this paper, we present CENTERA, a CENtralized Trust-based Efficient Routing protocol with an appropriate authentication scheme for wireless sensor networks (WSN). CENTERA utilizes the more powerful base station (BS) to gather minimal neighbor trust information from nodes and calculate the best routes after isolating different types of “bad” nodes. By periodically accumulating these simple local observations and approximating the nodes' battery lives, the BS draws a global view of the network, calculates three quality metrics—maliciousness, cooperation, and compatibility—and evaluates the Data Trust and Forwarding Trust values of each node. Based on these metrics, the BS isolates “bad”, “misbehaving” or malicious nodes for a certain period, and put some nodes on probation. CENTERA increases the node's bad/probation level with repeated “bad” behavior, and decreases it otherwise. Then it uses a very efficient method to distribute the routing information to “good” nodes. Based on its target environment, and if required, CENTERA uses an authentication scheme suitable for severely constrained nodes, ranging from the symmetric RC5 for safe environments under close administration, to pairing-based cryptography (PBC) for hostile environments with a strong attacker model. We simulate CENTERA using TOSSIM and verify its correctness and show some energy calculations. PMID:25648712

  4. CENTERA: a centralized trust-based efficient routing protocol with authentication for wireless sensor networks.

    Science.gov (United States)

    Tajeddine, Ayman; Kayssi, Ayman; Chehab, Ali; Elhajj, Imad; Itani, Wassim

    2015-02-02

    In this paper, we present CENTERA, a CENtralized Trust-based Efficient Routing protocol with an appropriate authentication scheme for wireless sensor networks (WSN). CENTERA utilizes the more powerful base station (BS) to gather minimal neighbor trust information from nodes and calculate the best routes after isolating different types of "bad" nodes. By periodically accumulating these simple local observations and approximating the nodes' battery lives, the BS draws a global view of the network, calculates three quality metrics-maliciousness, cooperation, and compatibility-and evaluates the Data Trust and Forwarding Trust values of each node. Based on these metrics, the BS isolates "bad", "misbehaving" or malicious nodes for a certain period, and put some nodes on probation. CENTERA increases the node's bad/probation level with repeated "bad" behavior, and decreases it otherwise. Then it uses a very efficient method to distribute the routing information to "good" nodes. Based on its target environment, and if required, CENTERA uses an authentication scheme suitable for severely constrained nodes, ranging from the symmetric RC5 for safe environments under close administration, to pairing-based cryptography (PBC) for hostile environments with a strong attacker model. We simulate CENTERA using TOSSIM and verify its correctness and show some energy calculations.

  5. Central FPGA-based Destination and Load Control in the LHCb MHz Event Readout

    CERN Document Server

    Jacobsson, Richard

    2012-01-01

    The readout strategy of the LHCb experiment [1] is based on complete event readout at 1 MHz [2]. Over 300 sub-detector readout boards transmit event fragments at 1 MHz over a commercial 70 Gigabyte/s switching network to a distributed event building and trigger processing farm with 1470 individual multi-core computer nodes [3]. In the original specifications, the readout was based on a pure push protocol. This paper describes the proposal, implementation, and experience of a powerful non-conventional mixture of a push and a pull protocol, akin to credit-based flow control. A high-speed FPGA-based central master module controls the event fragment packing in the readout boards, the assignment of the farm node destination for each event, and controls the farm load based on an asynchronous pull mechanism from each farm node. This dynamic readout scheme relies on generic event requests and the concept of node credit allowing load balancing and trigger rate regulation as a function of the global farm load. It also ...

  6. Branch-Based Centralized Data Collection for Smart Grids Using Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Kwangsoo Kim

    2015-05-01

    Full Text Available A smart grid is one of the most important applications in smart cities. In a smart grid, a smart meter acts as a sensor node in a sensor network, and a central device collects power usage from every smart meter. This paper focuses on a centralized data collection problem of how to collect every power usage from every meter without collisions in an environment in which the time synchronization among smart meters is not guaranteed. To solve the problem, we divide a tree that a sensor network constructs into several branches. A conflict-free query schedule is generated based on the branches. Each power usage is collected according to the schedule. The proposed method has important features: shortening query processing time and avoiding collisions between a query and query responses. We evaluate this method using the ns-2 simulator. The experimental results show that this method can achieve both collision avoidance and fast query processing at the same time. The success rate of data collection at a sink node executing this method is 100%. Its running time is about 35 percent faster than that of the round-robin method, and its memory size is reduced to about 10% of that of the depth-first search method.

  7. Separating temporal and topological effects in walk-based network centrality.

    Science.gov (United States)

    Colman, Ewan R; Charlton, Nathaniel

    2016-07-01

    The recently introduced concept of dynamic communicability is a valuable tool for ranking the importance of nodes in a temporal network. Two metrics, broadcast score and receive score, were introduced to measure the centrality of a node with respect to a model of contagion based on time-respecting walks. This article examines the temporal and structural factors influencing these metrics by considering a versatile stochastic temporal network model. We analytically derive formulas to accurately predict the expectation of the broadcast and receive scores when one or more columns in a temporal edge-list are shuffled. These methods are then applied to two publicly available data sets and we quantify how much the centrality of each individual depends on structural or temporal influences. From our analysis, we highlight two practical contributions: a way to control for temporal variation when computing dynamic communicability and the conclusion that the broadcast and receive scores can, under a range of circumstances, be replaced by the row and column sums of the matrix exponential of a weighted adjacency matrix given by the data.

  8. Branch-based centralized data collection for smart grids using wireless sensor networks.

    Science.gov (United States)

    Kim, Kwangsoo; Jin, Seong-il

    2015-05-21

    A smart grid is one of the most important applications in smart cities. In a smart grid, a smart meter acts as a sensor node in a sensor network, and a central device collects power usage from every smart meter. This paper focuses on a centralized data collection problem of how to collect every power usage from every meter without collisions in an environment in which the time synchronization among smart meters is not guaranteed. To solve the problem, we divide a tree that a sensor network constructs into several branches. A conflict-free query schedule is generated based on the branches. Each power usage is collected according to the schedule. The proposed method has important features: shortening query processing time and avoiding collisions between a query and query responses. We evaluate this method using the ns-2 simulator. The experimental results show that this method can achieve both collision avoidance and fast query processing at the same time. The success rate of data collection at a sink node executing this method is 100%. Its running time is about 35 percent faster than that of the round-robin method, and its memory size is reduced to about 10% of that of the depth-first search method.

  9. Breastfeeding duration and cognitive, language and motor development at 18 months of age: Rhea mother-child cohort in Crete, Greece.

    Science.gov (United States)

    Leventakou, Vasiliki; Roumeliotaki, Theano; Koutra, Katerina; Vassilaki, Maria; Mantzouranis, Evangelia; Bitsios, Panos; Kogevinas, Manolis; Chatzi, Leda

    2015-03-01

    Breast feeding duration has been associated with improved cognitive development in children. However, few population-based prospective studies have evaluated dose-response relationships of breastfeeding duration with language and motor development at early ages, and results are discrepant. The study uses data from the prospective mother-child cohort ('Rhea' study) in Crete, Greece. 540 mother-child pairs were included in the present analysis. Information about parental and child characteristics and breastfeeding practices was obtained by interview-administered questionnaires. Trained psychologists assessed cognitive, language and motor development by using the Bayley Scales of Infant Toddler Development (3rd edition) at the age of 18 months. Duration of breast feeding was linearly positively associated with all the Bayley scales, except of gross motor. The association persisted after adjustment for potential confounders with an increase of 0.28 points in the scale of cognitive development (β=0.28; 95% CI 0.01 to 0.55), 0.29 points in the scale of receptive communication (β=0.29; 95% CI 0.04 to 0.54), 0.30 points in the scale of expressive communication (β=0.30; 95% CI 0.04 to 0.57) and 0.29 points in the scale of fine motor development (β=0.29; 95% CI 0.02 to 0.56) per accumulated month of breast feeding. Children who were breast fed longer than 6 months had a 4.44-point increase in the scale of fine motor development (β=4.44; 95% CI 0.06 to 8.82) compared with those never breast fed. Longer duration of breast feeding was associated with increased scores in cognitive, language and motor development at 18 months of age, independently from a wide range of parental and infant characteristics. Additional longitudinal studies and trials are needed to confirm these results. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  10. Efficient crop type mapping based on remote sensing in the Central Valley, California

    Science.gov (United States)

    Zhong, Liheng

    Most agricultural systems in California's Central Valley are purposely flexible and intentionally designed to meet the demands of dynamic markets. Agricultural land use is also impacted by climate change and urban development. As a result, crops change annually and semiannually, which makes estimating agricultural water use difficult, especially given the existing method by which agricultural land use is identified and mapped. A minor portion of agricultural land is surveyed annually for land-use type, and every 5 to 8 years the entire valley is completely evaluated. So far no effort has been made to effectively and efficiently identify specific crop types on an annual basis in this area. The potential of satellite imagery to map agricultural land cover and estimate water usage in the Central Valley is explored. Efforts are made to minimize the cost and reduce the time of production during the mapping process. The land use change analysis shows that a remote sensing based mapping method is the only means to map the frequent change of major crop types. The traditional maximum likelihood classification approach is first utilized to map crop types to test the classification capacity of existing algorithms. High accuracy is achieved with sufficient ground truth data for training, and crop maps of moderate quality can be timely produced to facilitate a near-real-time water use estimate. However, the large set of ground truth data required by this method results in high costs in data collection. It is difficult to reduce the cost because a trained classification algorithm is not transferable between different years or different regions. A phenology based classification (PBC) approach is developed which extracts phenological metrics from annual vegetation index profiles and identifies crop types based on these metrics using decision trees. According to the comparison with traditional maximum likelihood classification, this phenology-based approach shows great advantages

  11. Situational Lightning Climatologies for Central Florida: Phase IV: Central Florida Flow Regime Based Climatologies of Lightning Probabilities

    Science.gov (United States)

    Bauman, William H., III

    2009-01-01

    The threat of lightning is a daily concern during the warm season in Florida. Research has revealed distinct spatial and temporal distributions of lightning occurrence that are strongly influenced by large-scale atmospheric flow regimes. Previously, the Applied Meteorology Unit (AMU) calculated the gridded lightning climatologies based on seven flow regimes over Florida for 1-, 3- and 6-hr intervals in 5-, 10-, 20-, and 30-NM diameter range rings around the Shuttle Landing Facility (SLF) and eight other airfields in the National Weather Service in Melbourne (NWS MLB) county warning area (CWA). In this update to the work, the AMU recalculated the lightning climatologies for using individual lightning strike data to improve the accuracy of the climatologies. The AMU included all data regardless of flow regime as one of the stratifications, added monthly stratifications, added three years of data to the period of record and used modified flow regimes based work from the AMU's Objective Lightning Probability Forecast Tool, Phase II. The AMU made changes so the 5- and 10-NM radius range rings are consistent with the aviation forecast requirements at NWS MLB, while the 20- and 30-NM radius range rings at the SLF assist the Spaceflight Meteorology Group in making forecasts for weather Flight Rule violations during Shuttle landings. The AMU also updated the graphical user interface with the new data.

  12. Evidence-based measures to prevent central line-associated bloodstream infections: a systematic review.

    Science.gov (United States)

    Perin, Daniele Cristina; Erdmann, Alacoque Lorenzini; Higashi, Giovana Dorneles Callegaro; Sasso, Grace Teresinha Marcon Dal

    2016-09-01

    to identify evidence-based care to prevent CLABSI among adult patients hospitalized in ICUs. systematic review conducted in the following databases: PubMed, Scopus, Cinahl, Web of Science, Lilacs, Bdenf and Cochrane Studies addressing care and maintenance of central venous catheters, published from January 2011 to July 2014 were searched. The 34 studies identified were organized in an instrument and assessed by using the classification provided by the Joanna Briggs Institute. the studies presented care bundles including elements such as hand hygiene and maximal barrier precautions; multidimensional programs and strategies such as impregnated catheters and bandages and the involvement of facilities in and commitment of staff to preventing infections. care bundles coupled with education and the commitment of both staff and institutions is a strategy that can contribute to decreased rates of central line-associated bloodstream infections among adult patients hospitalized in intensive care units. identificar evidências de cuidados para prevenção de infecção de corrente sanguínea relacionada a cateter venoso central em pacientes adultos em Unidades de Terapia Intensiva. revisão Sistemática realizada por meio de busca nas bases de dados Pubmed, Scopus, Cinahl, Web of Science, Lilacs, Bdenf e Cochrane. Foram buscadas pesquisas com cuidados com a cateterização e manutenção do cateter venoso central, publicados de janeiro de 2011 a julho de 2014. Os 34 estudos incluídos foram organizados em um instrumento e avaliados por meio da classificação do The Joanna Briggs Institute. os estudos apresentaram bundles de cuidados com elementos como a higiene das mãos e precauções máximas de barreira; programas multidimensionais e estratégias como cateteres e curativos impregnados e o envolvimento da instituição e engajamento da equipe nos esforços para prevenção de infecção. os cuidados no formato de bundles aliados com a educação e engajamento da equipe e

  13. Normal Development of Sutures and synchondroses in the central skull base : CT study

    International Nuclear Information System (INIS)

    Roh, Hong Gee; Kim, Hyung Jin; Kang, Jee Hee; Lee, Kyung Hee; Lim, Myung Kwan; Cho, Young Kuk; Ok, Cheol Su; Suh, Chang Hae

    2000-01-01

    To evaluate the developmental patterns of the sutures and synchondroses in the central skull base. We evaluated the CT scans of 109 children (age range 29 days to 15 years) with no skull base abnormality who had undergone axial CT of the skull base with 1-mm collimation. Using a five-tier scheme, we analyzed the developmental patterns of the 18 sutures and synchondroses related to the sphenoid and occipital bones. Fusion of the sutures and synchondroses related to the sphenoid bone progressed rapidly during the first two years. Thereafter, changes in the sphenoid bone were dominated by pneumatization of the sphenoid sinus. Fusion of the synchondroses within the sphenoid body, including intersphenoidal, intrapresphenoidal, intrapostsphenoidal synchondrosis occurred early and in most cases was graded ≥3D4. Fusion of the sphenosquamosal, sphenoethmoidal, and frontosphenoidal sutures was delayed, and residual sclerosis was a common finding. Except for Kerckring-supraoccipital synchondrosis, fusion of the six sutures and synchondroses related to the occipital bone occurred more gradually than that of those related to the sphenoid bone. Among these, fusion of the occipitomastoidal suture and petro-occipital synchondrosis was the last to occur. A knowledge of the developmental patterns of sutures and synchondroses can help differentiate normal conditions from those such as fracture, osseous dysplasia, or congenital malformation, which are abnormal. Our results provide certain basic information about skull base maturity in children. (author)

  14. Caribou, individual-based modeling and mega-industry in central West Greenland

    DEFF Research Database (Denmark)

    Raundrup, Katrine; Nymand, Josephine; Nabe-Nielsen, Jacob

    in West Greenland. In a newly started PhD-project the focus will be the implementation of spatially explicit individual based modeling (IBM). The project relies on existing knowledge on caribou behavior and feeding ecology along with data on variations in the vegetation. By relating vegetation, snow......Spatial distribution of caribou (Rangifer tarandus groenlandicus) in West Greenland is a result of both short and long term changes in the Arctic landscape. To understand present distribution 40 satellite collars were deployed on 40 female caribou in the Akia-Maniitsoq herd, central West Greenland...... in an area. Further, enhanced or lowered hunting pressure, and changed weather conditions can be studied using IBM. Thus, both short and long term changes in the landscape will be studied and provide insights in how the specific spatial changes impact caribou in West Greenland....

  15. [The Development of Information Centralization and Management Integration System for Monitors Based on Wireless Sensor Network].

    Science.gov (United States)

    Xu, Xiu; Zhang, Honglei; Li, Yiming; Li, Bin

    2015-07-01

    Developed the information centralization and management integration system for monitors of different brands and models with wireless sensor network technologies such as wireless location and wireless communication, based on the existing wireless network. With adaptive implementation and low cost, the system which possesses the advantages of real-time, efficiency and elaboration is able to collect status and data of the monitors, locate the monitors, and provide services with web server, video server and locating server via local network. Using an intranet computer, the clinical and device management staffs can access the status and parameters of monitors. Applications of this system provide convenience and save human resource for clinical departments, as well as promote the efficiency, accuracy and elaboration for the device management. The successful achievement of this system provides solution for integrated and elaborated management of the mobile devices including ventilator and infusion pump.

  16. The Exchange Data Communication System based on Centralized Database for the Meat Industry

    Science.gov (United States)

    Kobayashi, Yuichi; Taniguchi, Yoji; Terada, Shuji; Komoda, Norihisa

    We propose applying the EDI system that is based on centralized database and supports conversion of code data to the meat industry. This system makes it possible to share exchange data on beef between enterprises from producers to retailers by using Web EDI technology. In order to efficiently convert code direct conversion of a sender's code to a receiver's code using a code map is used. This system that mounted this function has been implemented in September 2004. Twelve enterprises including retailers, and processing traders, and wholesalers were using the system as of June 2005. In this system, the number of code maps relevant to the introductory cost of the code conversion function was lower than the theoretical value and were close to the case that a standard code is mediated.

  17. Satellite-based detection of volcanic sulphur dioxide from recent eruptions in Central and South America

    Directory of Open Access Journals (Sweden)

    D. Loyola

    2008-01-01

    Full Text Available Volcanic eruptions can emit large amounts of rock fragments and fine particles (ash into the atmosphere, as well as several gases, including sulphur dioxide (SO2. These ejecta and emissions are a major natural hazard, not only to the local population, but also to the infrastructure in the vicinity of volcanoes and to aviation. Here, we describe a methodology to retrieve quantitative information about volcanic SO2 plumes from satellite-borne measurements in the UV/Visible spectral range. The combination of a satellite-based SO2 detection scheme and a state-of-the-art 3D trajectory model enables us to confirm the volcanic origin of trace gas signals and to estimate the plume height and the effective emission height. This is demonstrated by case-studies for four selected volcanic eruptions in South and Central America, using the GOME, SCIAMACHY and GOME-2 instruments.

  18. Tourism Communication in Community Based Tourism in Dieng Community, Central Java, Indonesia

    Directory of Open Access Journals (Sweden)

    Manik Sunuantari

    2017-08-01

    Full Text Available To encourage a community’s role in the field of tourism, the local government of Central Java, Indonesia promotes a Community Based Tourism (CBT as a tourism development for the sustainable economy. It involves the community in decision-making processes, especially related to the acquisition of income, employment, and the preservation of the environment, and culture of the indigenous people. This research aimed to determine communication activities in the implementation of CBT. The theory used was tourism communication using Attention, Interest, Desire, Action (AIDA model. Then, the method was a case study by choosing Dieng as a tourist destination, and the tourism communication activities were undertaken in Dieng’s society, especially in the activities of Dieng Culture Festival (DCF. The results show that the tourism communication activities involving the community, POKDARWIS (Kelompok Sadar Wisata - Tourism Awareness Group, tourism advocates, and local governments should pay attention to the cultural and natural tourism potentials, and empower the local communities.

  19. A GPU-based solution for fast calculation of the betweenness centrality in large weighted networks

    Directory of Open Access Journals (Sweden)

    Rui Fan

    2017-12-01

    Full Text Available Betweenness, a widely employed centrality measure in network science, is a decent proxy for investigating network loads and rankings. However, its extremely high computational cost greatly hinders its applicability in large networks. Although several parallel algorithms have been presented to reduce its calculation cost for unweighted networks, a fast solution for weighted networks, which are commonly encountered in many realistic applications, is still lacking. In this study, we develop an efficient parallel GPU-based approach to boost the calculation of the betweenness centrality (BC for large weighted networks. We parallelize the traditional Dijkstra algorithm by selecting more than one frontier vertex each time and then inspecting the frontier vertices simultaneously. By combining the parallel SSSP algorithm with the parallel BC framework, our GPU-based betweenness algorithm achieves much better performance than its CPU counterparts. Moreover, to further improve performance, we integrate the work-efficient strategy, and to address the load-imbalance problem, we introduce a warp-centric technique, which assigns many threads rather than one to a single frontier vertex. Experiments on both realistic and synthetic networks demonstrate the efficiency of our solution, which achieves 2.9× to 8.44× speedups over the parallel CPU implementation. Our algorithm is open-source and free to the community; it is publicly available through https://dx.doi.org/10.6084/m9.figshare.4542405. Considering the pervasive deployment and declining price of GPUs in personal computers and servers, our solution will offer unprecedented opportunities for exploring betweenness-related problems and will motivate follow-up efforts in network science.

  20. Measuring Long-Term Impact Based on Network Centrality: Unraveling Cinematic Citations

    Science.gov (United States)

    Spitz, Andreas; Horvát, Emőke-Ágnes

    2014-01-01

    Traditional measures of success for film, such as box-office revenue and critical acclaim, lack the ability to quantify long-lasting impact and depend on factors that are largely external to the craft itself. With the growing number of films that are being created and large-scale data becoming available through crowd-sourced online platforms, an endogenous measure of success that is not reliant on manual appraisal is of increasing importance. In this article we propose such a ranking method based on a combination of centrality indices. We apply the method to a network that contains several types of citations between more than 40,000 international feature films. From this network we derive a list of milestone films, which can be considered to constitute the foundations of cinema. In a comparison to various existing lists of ‘greatest’ films, such as personal favourite lists, voting lists, lists of individual experts, and lists deduced from expert polls, the selection of milestone films is more diverse in terms of genres, actors, and main creators. Our results shed light on the potential of a systematic quantitative investigation based on cinematic influences in identifying the most inspiring creations in world cinema. In a broader perspective, we introduce a novel research question to large-scale citation analysis, one of the most intriguing topics that have been at the forefront of scientific enquiries for the past fifty years and have led to the development of various network analytic methods. In doing so, we transfer widely studied approaches from citation analysis to the the newly emerging field of quantification efforts in the arts. The specific contribution of this paper consists in modelling the multidimensional cinematic references as a growing multiplex network and in developing a methodology for the identification of central films in this network. PMID:25295877

  1. Measuring long-term impact based on network centrality: unraveling cinematic citations.

    Directory of Open Access Journals (Sweden)

    Andreas Spitz

    Full Text Available Traditional measures of success for film, such as box-office revenue and critical acclaim, lack the ability to quantify long-lasting impact and depend on factors that are largely external to the craft itself. With the growing number of films that are being created and large-scale data becoming available through crowd-sourced online platforms, an endogenous measure of success that is not reliant on manual appraisal is of increasing importance. In this article we propose such a ranking method based on a combination of centrality indices. We apply the method to a network that contains several types of citations between more than 40,000 international feature films. From this network we derive a list of milestone films, which can be considered to constitute the foundations of cinema. In a comparison to various existing lists of 'greatest' films, such as personal favourite lists, voting lists, lists of individual experts, and lists deduced from expert polls, the selection of milestone films is more diverse in terms of genres, actors, and main creators. Our results shed light on the potential of a systematic quantitative investigation based on cinematic influences in identifying the most inspiring creations in world cinema. In a broader perspective, we introduce a novel research question to large-scale citation analysis, one of the most intriguing topics that have been at the forefront of scientific enquiries for the past fifty years and have led to the development of various network analytic methods. In doing so, we transfer widely studied approaches from citation analysis to the the newly emerging field of quantification efforts in the arts. The specific contribution of this paper consists in modelling the multidimensional cinematic references as a growing multiplex network and in developing a methodology for the identification of central films in this network.

  2. Results-Based Financing in Mozambique’s Central Medical Store: A Review After 1 Year

    Science.gov (United States)

    Spisak, Cary; Morgan, Lindsay; Eichler, Rena; Rosen, James; Serumaga, Brian; Wang, Angela

    2016-01-01

    ABSTRACT Background: Public health commodity supply chains are typically weak in low-income countries, partly because they have many disparate yet interdependent functions and components. Approaches to strengthening supply chains in such settings have often fallen short—they address technical weaknesses, but not the incentives that motivate staff to perform better. Methods: We reviewed the first year of a results-based financing (RBF) program in Mozambique, which began in January 2013. The program aimed to improve the performance of the central medical store—Central de Medicamentos e Artigos Medicos (CMAM)—by realigning incentives. We completed in-depth interviews and focus group discussions with 33 key informants, including representatives from CMAM and donor agencies, and collected quantitative data on performance measures and use of funds. Implementation: The RBF agreement linked CMAM performance payments to quarterly results on 5 performance indicators related to supply planning, distribution planning, and warehouse management. RBF is predicated on the theory that a combination of carrot and stick—i.e., shared financial incentives, plus increased accountability for results—will spur changes in behavior. Important design elements: (1) indicators were measured against quarterly targets, and payments were made only for indicators that met those targets; (2) targets were set based on documented performance, at levels that could be reasonably attained, yet pushed for improvement; (3) payment was shared with and dependent on all staff, encouraging teamwork and collaboration; (4) results were validated by verifiable data sources; and (5) CMAM had discretion over how to use the funds. Findings: We found that CMAM’s performance continually improved over baseline and that CMAM achieved many of its performance targets, for example, timely submission of quarterly supply and distribution planning reports. Warehouse indicators, such as inventory management and

  3. Results-Based Financing in Mozambique's Central Medical Store: A Review After 1 Year.

    Science.gov (United States)

    Spisak, Cary; Morgan, Lindsay; Eichler, Rena; Rosen, James; Serumaga, Brian; Wang, Angela

    2016-03-01

    Public health commodity supply chains are typically weak in low-income countries, partly because they have many disparate yet interdependent functions and components. Approaches to strengthening supply chains in such settings have often fallen short-they address technical weaknesses, but not the incentives that motivate staff to perform better. We reviewed the first year of a results-based financing (RBF) program in Mozambique, which began in January 2013. The program aimed to improve the performance of the central medical store-Central de Medicamentos e Artigos Medicos (CMAM)-by realigning incentives. We completed in-depth interviews and focus group discussions with 33 key informants, including representatives from CMAM and donor agencies, and collected quantitative data on performance measures and use of funds. The RBF agreement linked CMAM performance payments to quarterly results on 5 performance indicators related to supply planning, distribution planning, and warehouse management. RBF is predicated on the theory that a combination of carrot and stick-i.e., shared financial incentives, plus increased accountability for results-will spur changes in behavior. Important design elements: (1) indicators were measured against quarterly targets, and payments were made only for indicators that met those targets; (2) targets were set based on documented performance, at levels that could be reasonably attained, yet pushed for improvement; (3) payment was shared with and dependent on all staff, encouraging teamwork and collaboration; (4) results were validated by verifiable data sources; and (5) CMAM had discretion over how to use the funds. We found that CMAM's performance continually improved over baseline and that CMAM achieved many of its performance targets, for example, timely submission of quarterly supply and distribution planning reports. Warehouse indicators, such as inventory management and order fulfillment, proved more challenging but were nonetheless

  4. Debris flow susceptibility assessment based on an empirical approach in the central region of South Korea

    Science.gov (United States)

    Kang, Sinhang; Lee, Seung-Rae

    2018-05-01

    Many debris flow spreading analyses have been conducted during recent decades to prevent damage from debris flows. An empirical approach that has been used in various studies on debris flow spreading has advantages such as simple data acquisition and good applicability for large areas. In this study, a GIS-based empirical model that was developed at the University of Lausanne (Switzerland) is used to assess the debris flow susceptibility. Study sites are classified based on the types of soil texture or geological conditions, which can indirectly consider geotechnical or rheological properties, to supplement the weaknesses of Flow-R which neglects local controlling factors. The mean travel angle for each classification is calculated from a debris flow inventory map. The debris flow susceptibility is assessed based on changes in the flow-direction algorithm, an inertial function with a 5-m DEM resolution. A simplified friction-limited model was applied to the runout distance analysis by using the appropriate travel angle for the corresponding classification with a velocity limit of 28 m/s. The most appropriate algorithm combinations that derived the highest average of efficiency and sensitivity for each classification are finally determined by applying a confusion matrix with the efficiency and the sensitivity to the results of the susceptibility assessment. The proposed schemes can be useful for debris flow susceptibility assessment in both the study area and the central region of Korea, which has similar environmental factors such as geological conditions, topography and rainfall characteristics to the study area.

  5. Not sending the message: A low prevalence of strength-based exercise participation in rural and regional Central Queensland.

    Science.gov (United States)

    Dalbo, Vincent J; Czerepusko, James B; Tucker, Patrick S; Kingsley, Michael I; Moon, Jordan R; Young, Kaelin; Scanlan, Aaron T

    2015-10-01

    The primary aim of this study was to determine the prevalence of current strength-based exercise in rural and regional populations of Central Queensland. The secondary aim was to examine the proportion of residents from various demographic groups who currently partake in strength-based exercise to allow for targeted strength training campaigns. A cross-sectional, survey-based experimental design was followed. Rural and regional Australia. Rural and regional community-dwelling individuals living in Central Queensland and aged 18 years and older. Survey data was collected in October and November 2010 as part of the Central Queensland University Social Survey. Strength-based exercise participation, gender, age, income, years of education, self-reported physical activity and perception of health. Participation in strength-based exercise was 13.2%. Women were less likely to partake in strength-based exercise than male, and ≥55 year old adults were less likely to partake in strength-based exercise than 18-34 year old adults. Participation in strength-based exercise was found to increase with years of education, self-reported physical activity and self-rated health. The prevalence of adults in rural and regional Central Queensland engaging in strength-based exercise is low. Exercise physiologists, clinicians and government officials must work together to ensure that this form of exercise is acknowledged as a vital component of health in rural and regional areas. © 2015 National Rural Health Alliance Inc.

  6. Abundance, zoonotic potential and risk factors of intestinal parasitism amongst dog and cat populations: The scenario of Crete, Greece.

    Science.gov (United States)

    Kostopoulou, Despoina; Claerebout, Edwin; Arvanitis, Dimitrios; Ligda, Panagiota; Voutzourakis, Nikolaos; Casaert, Stijn; Sotiraki, Smaragda

    2017-01-25

    The objectives of this study were to evaluate the prevalence and infection intensity of intestinal parasites in different dog and cat populations in Crete, Greece, estimate the zoonotic risk and identify risk factors. Faecal samples from shelter, household and shepherd dogs and shelter and household cats were analyzed using sedimentation/flotation techniques. Giardia and Cryptosporidium were detected by a quantitative direct immunofluorescence assay (IFA). PCR and sequencing was performed to evaluate the zoonotic potential of Giardia and Cryptosporidium positive samples. Totals of 879 dog and 264 cat faecal samples were examined. In dogs, the overall prevalence was 25.2% (CI: 22.4-28.1) for Giardia spp.; 9.2% (CI: 7.3-11.1) for Ancylostoma/Uncinaria spp.; 7.6% (CI: 5.9-9.4) for Toxocara spp.; 5.9% (CI: 4.4-7.5) for Cryptosporidium spp.; 4.6% (CI: 3.2-5.9) for Cystoisospora spp.; 2.7% (CI: 1.7-3.8) for Toxascaris leonina; 1.7% (CI: 0.9-2.6) for Capillaria spp.; 0.8% (CI: 0.2-1.4) for taeniid eggs; 0.2% (CI: 0-0.5) for Dipylidium caninum; and 0.1% (CI: 0-0.3) for Strongyloides stercoralis. In cats, the prevalence was 20.5% (CI: 15.6-25.3) for Giardia spp.; 9.5% (CI: 5.9-13.0) for Cystoisospora spp.; 8.3% (CI: 5.0-11.7) for Toxocara spp.; 7.6% (CI: 4.4-10.8) for Ancylostoma/Uncinaria spp.; 6.8% (CI: 3.8-9.9) for Cryptosporidium spp.; 4.2% (CI: 1.8-6.6) for Capillaria spp.; 0.8% (CI: 0-1.8) for taeniid eggs; and 0.4% (CI: 0-1.1) for Hammondia/Toxoplasma. Concerning the risk factors evaluated, there was a negative association between age and Giardia infection and between age and T. leonina infection intensity for dogs. Sequencing results revealed the presence of mainly animal-specific G. duodenalis assemblages C and D in dogs and assemblages F, C and BIV-like in cats, with only a limited number of (co-)infections with assemblage A. As for Cryptosporidium, the dog-specific C. canis and the pig-specific C. scrofarum were detected in dogs and the cat-specific C. felis was

  7. The PCR-Based Diagnosis of Central Nervous System Tuberculosis: Up to Date

    Directory of Open Access Journals (Sweden)

    Teruyuki Takahashi

    2012-01-01

    Full Text Available Central nervous system (CNS tuberculosis, particularly tuberculous meningitis (TBM, is the severest form of Mycobacterium tuberculosis (M.Tb infection, causing death or severe neurological defects in more than half of those affected, in spite of recent advancements in available anti-tuberculosis treatment. The definitive diagnosis of CNS tuberculosis depends upon the detection of M.Tb bacilli in the cerebrospinal fluid (CSF. At present, the diagnosis of CNS tuberculosis remains a complex issue because the most widely used conventional “gold standard” based on bacteriological detection methods, such as direct smear and culture identification, cannot rapidly detect M.Tb in CSF specimens with sufficient sensitivity in the acute phase of TBM. Recently, instead of the conventional “gold standard”, the various molecular-based methods including nucleic acid amplification (NAA assay technique, particularly polymerase chain reaction (PCR assay, has emerged as a promising new method for the diagnosis of CNS tuberculosis because of its rapidity, sensitivity and specificity. In addition, the innovation of nested PCR assay technique is worthy of note given its contribution to improve the diagnosis of CNS tuberculosis. In this review, an overview of recent progress of the NAA methods, mainly highlighting the PCR assay technique, was presented.

  8. Fabrication of paper-based analytical devices optimized by central composite design.

    Science.gov (United States)

    Hamedpour, Vahid; Leardi, Riccardo; Suzuki, Koji; Citterio, Daniel

    2018-04-30

    In this work, an application of a design of experiments approach for the optimization of an isoniazid assay on a single-area inkjet-printed paper-based analytical device (PAD) is described. For this purpose, a central composite design was used for evaluation of the effect of device geometry and amount of assay reagents on the efficiency of the proposed device. The factors of interest were printed length, width, and sampling volume as factors related to device geometry, and amounts of the assay reagents polyvinyl alcohol (PVA), NH4OH, and AgNO3. Deposition of the assay reagents was performed by a thermal inkjet printer. The colorimetric assay mechanism of this device is based on the chemical interaction of isoniazid, ammonium hydroxide, and PVA with silver ions to induce the formation of yellow silver nanoparticles (AgNPs). The in situ-formed AgNPs can be easily detected by the naked eye or with a simple flat-bed scanner. Under optimal conditions, the calibration curve was linear in the isoniazid concentration range 0.03-10 mmol L-1 with a relative standard deviation of 3.4% (n = 5 for determination of 1.0 mmol L-1). Finally, the application of the proposed device for isoniazid determination in pharmaceutical preparations produced satisfactory results.

  9. Assessing the ecological base flow in an experimental watershed of Central Taiwan

    Science.gov (United States)

    Wei, Chiang; Yang, Ping-Shih; Tian, Pei-Ling

    2010-05-01

    The ecological base flow is crucial for the assessment and design for habitat rehabilitation and recovery. The amount of discharge affects the aquatic creatures and may damage the existence and balance of the community under extreme low conditions. Aquatic insect is selected as the target species in this study to evaluate the influence of the discharge and to estimate the ecological base flow. The distribution of the number of species and abundance (density) versus discharge is assessed to define the critical discharge. A stream located at the alpine area in central Taiwan is selected as the study area to evaluate the base flow. From the preliminary data (Aug 2008 to May 2009) collected from Creek C of Sitou watershed (area: 1.3 km^2) shows that the abundance of several species varies with the discharge. The dominate family and genus of aquatic insects is Baetidae (Order Ephemeroptera) and Baetis spp. that accounts for 26.3 and 17.2 %, respectively. The Hilsenhoff family biotic index (FBI) shows that the water quality is classified to "Excellent" and "Good" level while the EPT Index (Index of three orders: Ephemeroptera, Plecoptera, and Trichoptera) indicates that the stream is non-polluted. The discharge of base flow interpreted from the 90%, 95% and 96% curve of duration for the daily discharge is 0.1582, 0.0476 and 0.0378 cms; the threshold value evaluated by curve of abundance vs. discharge is 0.0154 cms. Consistent observations are yet to be collected to yield more accurate results.

  10. Epidemiology and molecular analysis of hepatitis A, B and C in a semi-urban and rural area of Crete.

    Science.gov (United States)

    Drositis, I; Bertsias, A; Lionis, C; Kouroumalis, E

    2013-12-01

    An observational seroepidemiological study was carried out in a well-defined primary-care district on the island of Crete in order to determine the recent endemicity of viral hepatitis in Cretan-population. The setting consisted of a semi-urban group and a remote & rural group. Serum samples were collected from 876 subjects (437 males, 439 females) aged 15 years or above. Subjects were randomly selected from the permanent population of the area that consisted of 5705 individuals. The aim was to measure the prevalence of selected viral-hepatitis markers. Hepatitis B surface-antigen (HBsAg) was found positive in twenty-nine individuals, (3.3%). Antibodies to hepatitis B virus core-antigen (HBcAb) were detected in 287 subjects (32.8%) and antibodies to hepatitis C virus (anti-HCV) were detected in nineteen subjects (2.2%). Seropositivities for the semi-urban group were: 3.4%, 19.1%, 2.1% and 3.2%, 48.8%, 2.2% in remote & rural group respectively. Virtually, all subjects >45 years old were seropositive for antibodies to hepatitis A, whereas approximately 80% of those in the 15-44 age-group were found to be seropositive. A threefold increase in the HBV exposure and carrier proportion was found in Cretan native-population and in rural-areas compared to older studies carried out in other rural-populations of the island. It is still unknown whether the recent economic crisis or the demographic changes in Cretan-population contributed to these findings. HCV endemicity remains relatively constant, however an alteration of hepatitis C genotypes was observed. Exposure to HAV was found to be higher in remote and rural areas compared to semi-urban areas. © 2013.

  11. Adolescent drinking, academic achievement and leisure time use by secondary education students in a rural area of Crete.

    Science.gov (United States)

    Koutra, Kleio; Papadovassilaki, Kyriaki; Kalpoutzaki, Pelagia; Kargatzi, Maria; Roumeliotaki, Theano; Koukouli, Sofia

    2012-01-01

    This study investigated the alcohol consumption of secondary education students and their relationship to school life and leisure time use with peers. A cross-sectional survey was conducted in March 2007, and the study population consisted of 14- to 19-year-old students living in an agricultural area of Crete. The final sample consisted of 117 individuals (response rate 90.0%). A short previously validated self-completion questionnaire was used collecting information on: personal and family characteristics; school progress; leisure time activities and relations with other adolescents; and alcohol consumption. Alcohol consumption differed significantly between male (75.5%) and female (25.8%) students (P students consuming alcohol was lower compared with those who did not, but the difference was not statistically significant (P = 0.066). Statistical evidence supported the hypothesis that students who consumed alcohol had more absences and this association was stronger for male students. The frequency of alcohol consumption was found to relate to the number of absences for both sexes. Male students who had been suspended from school were more likely to drink alcohol than those who had not been suspended. Statistical evidence also supported the hypotheses that students who spent their free time in cafeterias, bars or billiard halls were more likely to drink alcohol and also consume alcohol at higher frequencies than those that did not spend their free time this way (P = 0.002 and P students, families, schools, communities and the state better understand the real dimensions of the problem. © 2011 Blackwell Publishing Ltd.

  12. Characteristics and Composition of Atmospheric Aerosols in Phimai, Central Thailand During BASE-ASIA

    Science.gov (United States)

    Li, Can; Tsay, Si-Chee; Hsu, N. Christina; Kim, Jin Young; Howell, Steven G.; Huebert, Barry J.; Ji, Qiang; Jeong, Myeong-Jae; Wang, Sheng-Hsiang; Hansell, Richard A.; hide

    2012-01-01

    Popular summary: Atmospheric aerosols play an important role in the Earth's climate system, and can also have adverse effects on air quality and human health. The environmental impacts of aerosols, on the other hand, are highly regional, since their temporal/spatial distribution is inhomogeneous and highly depends on the regional emission sources. To better understand the effects of aerosols, intensive field experiments are necessary to characterize the chemical and physical properties on a region-by-region basis. From late February to early May in 2006, NASA/GSFC's SMARTLabs facility was deployed at a rural site in central Thailand, Southeast Asia, to conduct a field experiment dubbed BASE-ASIA (Biomass-burning Aerosols in South East-Asia: Smoke Impact Assessment). The group was joined by scientists from the University of Hawaii and other regional institutes. Comprehensive measurements were made during the experiment, including aerosol chemical composition, optical and microphysical properties, as well as surface energetics and local . meteorology. This study analyzes part of the data from the BASE-ASIA experiment. It was found that, even for the relatively remote rural site, the aerosol loading was still substantial. Besides agricultural burning in the area, industrial pollution near the Bangkok metropolitan area, about 200 km southeast of the site, and even long-range transport from China, also contribute to the area's aerosol loading. The results indicate that aerosol pollution has developed into a regional problem for northern Indochina, and may become more severe as the region's population and economy continue to grow. Abstract: Comprehensive measurements of atmospheric aerosols were made in Phimai, central Thailand (15.l83 N, 102.565 E, elevation: 206 m) during the BASE-ASIA field experiment from late February to early May in 2006. The observed aerosol loading was sizable for this rural site (mean aerosol scattering: 108 +/- 64 Mm(exp -1); absorption: 15

  13. Status and future transition of rapid urbanizing landscape in central Western Ghats - CA based approach

    Science.gov (United States)

    Bharath, S..; Rajan, K. S.; Ramachandra, T. V.

    2014-11-01

    The land use changes in forested landscape are highly complex and dynamic, affected by the natural, socio-economic, cultural, political and other factors. The remote sensing (RS) and geographical information system (GIS) techniques coupled with multi-criteria evaluation functions such as Markov-cellular automata (CA-Markov) model helps in analysing intensity, extent and future forecasting of human activities affecting the terrestrial biosphere. Karwar taluk of Central Western Ghats in Karnataka state, India has seen rapid transitions in its forest cover due to various anthropogenic activities, primarily driven by major industrial activities. A study based on Landsat and IRS derived data along with CA-Markov method has helped in characterizing the patterns and trends of land use changes over a period of 2004-2013, expected transitions was predicted for a set of scenarios through 2013-2022. The analysis reveals the loss of pristine forest cover from 75.51% to 67.36% (1973 to 2013) and increase in agriculture land as well as built-up area of 8.65% (2013), causing impact on local flora and fauna. The other factors driving these changes are the aggregated level of demand for land, local and regional effects of land use activities such as deforestation, improper practices in expansion of agriculture and infrastructure development, deteriorating natural resources availability. The spatio temporal models helped in visualizing on-going changes apart from prediction of likely changes. The CA-Markov based analysis provides us insights into the localized changes impacting these regions and can be useful in developing appropriate mitigation management approaches based on the modelled future impacts. This necessitates immediate measures for minimizing the future impacts.

  14. Evaluation results after seven years of operation for the permanent Hellenic Seismological Network of Crete (HSNC).

    Science.gov (United States)

    Vallianatos, F.; Hloupis, G.; Papadopoulos, I.

    2012-04-01

    The Hellenic arc and the adjacent areas of the Greek mainland are the most active in western Eurasia and some of the most seismically active zones of the world. The seismicity of South Aegean is extremely high and is characterised by the frequent occurrence of large shallow and intermediate depth earthquakes. Until 2004, the installed seismological stations from several providers (NOA, GEOFON, MEDNET) provide average interstation distance around 130km resulting to catalogues with minimum magnitude of completeness (Mc) equals to 3.7. Towards to the direction of providing dense and state of the art instrumental coverage of seismicity in the South Aegean, HSNC begun its operation in 2004. Today it consists of (12) permanent seismological stations equipped with short period and broadband seismographs coupled with 3rd generation 24bit data loggers as well as from (2) accelerographs . The addition of HSNC along with combined use of all the active networks in South Aegean area (NOA, GEOFON, AUTH) decrease the average interstation distance to 60km and provide catalogues with Mc≥3.2. Data transmission and telemetry is implemented by a hybrid network consisting of dedicated wired ADSL links as well as VSAT links by using a unique private satellite hub. Real time data spread over collaborating networks (AUTH) and laboratories (Department of Earth Science - UCL) while at the same time, events are appended automatically and manually to EMSC database. Additional value to the network is provided by means of prototype systems which deployed in-situ for the purposes of: a) Acquiring aftershock data in the minimum time after main event. This is a mobile seismological network called RaDeSeis (Rapid Deployment Seismological network) which consists of a central station acting also as the central communication hub and wifi coupled mobile stations. b) The development of dedicated hardware and software solutions for rapid installation times (around 1 hour for each station) leading to

  15. The contribution of a central pattern generator in a reflex-based neuromuscular model

    Science.gov (United States)

    Dzeladini, Florin; van den Kieboom, Jesse; Ijspeert, Auke

    2014-01-01

    Although the concept of central pattern generators (CPGs) controlling locomotion in vertebrates is widely accepted, the presence of specialized CPGs in human locomotion is still a matter of debate. An interesting numerical model developed in the 90s’ demonstrated the important role CPGs could play in human locomotion, both in terms of stability against perturbations, and in terms of speed control. Recently, a reflex-based neuro-musculo-skeletal model has been proposed, showing a level of stability to perturbations similar to the previous model, without any CPG components. Although exhibiting striking similarities with human gaits, the lack of CPG makes the control of speed/step length in the model difficult. In this paper, we hypothesize that a CPG component will offer a meaningful way of controlling the locomotion speed. After introducing the CPG component in the reflex model, and taking advantage of the resulting properties, a simple model for gait modulation is presented. The results highlight the advantages of a CPG as feedforward component in terms of gait modulation. PMID:25018712

  16. Centralized Gap Clearance Control for Maglev Based Steel-Plate Conveyance System

    Directory of Open Access Journals (Sweden)

    GUNEY, O. F.

    2017-08-01

    Full Text Available The conveyance of steel-plates is one of the potential uses of the magnetic levitation technology in industry. However, the electromagnetic levitation systems inherently show nonlinear feature and are unstable without an active control. Well-known U-shaped or E-shaped electromagnets cannot provide redundant levitation with multiple degrees of freedom. In this paper, to achieve the full redundant levitation of the steel plate, a quadruple configuration of U shaped electromagnets has been proposed. To resolve the issue of instability and attain more robust levitation, a centralized control algorithm based on a modified PID controller (I PD is designed for each degree of freedom by using the Manabe canonical polynomial technique. The model of the system is carried out using electromechanical energy conversion princi¬ples and verified by 3-D FEM analysis. An experimental bench is built up to test the system performance under trajectory tracking and external disturbance excitation. The results confirm the effectiveness of the proposed system and the control approach to obtain a full redundant levitation even in case of disturbances. The paper demonstrates the feasibility of the con¬veyance of steel plates by using the quadruple configuration of U-shaped electromagnets and shows the merits of I-PD controller both in stabilization and increased robust levitation.

  17. Enhancement of increments in spectral amplitude: further evidence for a mechanism based on central adaptation.

    Science.gov (United States)

    Carcagno, Samuele; Semal, Catherine; Demany, Laurent

    2013-01-01

    The threshold for detecting a tone in a multitone masker is lower when the masker-plus-signal stimulus is preceded by a copy of the masker. One potential explanation of this "enhancement" phenomenon is that the -precursor stimulus acts as a "template" of the subsequent masker, thus helping listeners to segregate the signal from the masker. To assess this idea, we measured enhancement for precursors that were perceptually similar to the masker and for precursors that were made dissimilar to the masker by gating their components asynchronously. We found that the two types of precursor produced similar amounts of enhancement. This was true not only when the precursor and the subsequent test stimulus were presented to the same ear but also when they were presented to opposite ears. In a second experiment, we checked that the precursors with asynchronously gated components were perceptually poor templates of the subsequent maskers. Listeners now had to discriminate between test stimuli -containing the same components as the precursor and test stimuli containing all but one of the precursor components. We found that in this experimental situation, where enhancement could play no role, gating the precursor components asynchronously disrupted performance. Overall, our results are inconsistent with the hypothesis that precursors producing enhancement are beneficial because they are used as perceptual templates of the masker. Our results are instead consistent with an -explanation of enhancement based on selective neural adaptation taking place at a central locus of the auditory system.

  18. Prevalence of maternal near miss and community-based risk factors in Central Uganda.

    Science.gov (United States)

    Nansubuga, Elizabeth; Ayiga, Natal; Moyer, Cheryl A

    2016-11-01

    To examine the prevalence of maternal near-miss (MNM) and its associated risk factors in a community setting in Central Uganda. A cross-sectional research design employing multi-stage sampling collected data from women aged 15-49 years in Rakai, Uganda, who had been pregnant in the 3years preceding the survey, conducted between August 10 and December 31, 2013. Additionally, in-depth interviews were conducted. WHO-based disease and management criteria were used to identify MNM. Binary logistic regression was used to predict MNM risk factors. Content analysis was performed for qualitative data. Survey data were collected from 1557 women and 40 in-depth interviews were conducted. The MNM prevalence was 287.7 per 1000 pregnancies; the majority of MNMs resulted from hemorrhage. Unwanted pregnancies, a history of MNM, primipara, pregnancy danger signs, Banyakore ethnicity, and a partner who had completed primary education only were associated with increased odds of MNM (all Pstudies employing organ-failure MNM-diagnostic criteria. These findings illustrate the need to look beyond mortality statistics when assessing maternal health outcomes. Concerted efforts to increase supervised deliveries, access to emergency obstetric care, and access to contraceptives are warranted. Copyright © 2016 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  19. CrisprGE: a central hub of CRISPR/Cas-based genome editing.

    Science.gov (United States)

    Kaur, Karambir; Tandon, Himani; Gupta, Amit Kumar; Kumar, Manoj

    2015-01-01

    CRISPR system is a powerful defense mechanism in bacteria and archaea to provide immunity against viruses. Recently, this process found a new application in intended targeting of the genomes. CRISPR-mediated genome editing is performed by two main components namely single guide RNA and Cas9 protein. Despite the enormous data generated in this area, there is a dearth of high throughput resource. Therefore, we have developed CrisprGE, a central hub of CRISPR/Cas-based genome editing. Presently, this database holds a total of 4680 entries of 223 unique genes from 32 model and other organisms. It encompasses information about the organism, gene, target gene sequences, genetic modification, modifications length, genome editing efficiency, cell line, assay, etc. This depository is developed using the open source LAMP (Linux Apache MYSQL PHP) server. User-friendly browsing, searching facility is integrated for easy data retrieval. It also includes useful tools like BLAST CrisprGE, BLAST NTdb and CRISPR Mapper. Considering potential utilities of CRISPR in the vast area of biology and therapeutics, we foresee this platform as an assistance to accelerate research in the burgeoning field of genome engineering. © The Author(s) 2015. Published by Oxford University Press.

  20. Incidence and mechanism of central pontine myelinolysis based on analysis of MRI images and risk factors

    Energy Technology Data Exchange (ETDEWEB)

    Kondo, Masato [Akita Univ. (Japan). School of Medicine

    2000-02-01

    In this study, the incidence of central pontine myelinolysis (CPM)-like lesions on MRI images was studied in 1917 subjects, 1,500 of which were psychiatric patients and 417 were patients attending a brain health examination. The CPM-like lesions were first classified into four groups based on the characteristics of their MRI images: group 1 showed symmetrical lesions on both T1 low and T2 high images and were considered to be typical CPM; group 2 showed symmetrical high intensity lesions only on T2 images; group 3 had asymmetrical lesions only on T2 images; and group 4 had asymmetrical lesions on both T1 low and T2 high images. Furthermore, the relationships of each group with particular risk factors, such as alcoholism, hypertension, hyperlipidemia were statistically analysed. The cause of CPM-like features in the MRI images were discussed. Among our subjects, the incidence of CPM-like lesions was 3.8%, and that of group 1 was 1.2%. Significant correlations between group 1 and alcoholism, and group 3 and 4 with brain ischemic lesions were observed. A previous hypothesis that group 2 may be a premature state of CPM is not supported by our results. (author)

  1. Paleoenvironment of Tanjung Formation Barito Basin- Central Kalimantan Based on palynological data

    Directory of Open Access Journals (Sweden)

    Winantris Winantris

    2017-06-01

    Full Text Available The research area is located in the Muara Teweh, North Barito, Central Kalimantan. The cocking coal deposits are well known as they were produced from this area.  Upper part of Tanjung Formation is target coal production. The study objectives are to analyze paleoenvironment and to determine the relative age of coal deposits based on palynological data. Preparing palinological analysis used standard procedure by hydrofluoric acid method.Palynomorphs data  grouped into six types of ecology, and the sequence is as follows ; fresh water and lowland (41,75 %, brackish water  swamp (30,10%, Peat and freshwater swamp (17,96%, marine element (7,77 %, back mangrove (1,46% and upland element (0,97. Palmae pollen is very dominant, especially from freshwater and peat swamp that grow around coastal area i.e. Dicolcopollis, Proxapertites cursus, Proxapertites operculatus, Longapertites and Palmaepollenites kutchensis. Although marine  fossil found, but the frequency  less than one percent,  that was the  evidence of influence sea water to swamp area. The palynomorphs indicate the coal sedimented at upper delta plain.  Fossil index of relative age consist of    Proxapertites cursus, Proxapertites operculatus, Magnastriatites howardi Verrucatosporites usmensis, Retistephanocolpites , and Ixonantes type which refer to Late Eocene.

  2. Development of a central PC-based system for reactor signal monitoring and analysis

    International Nuclear Information System (INIS)

    Karim, A.; Ansari, S.A.; Baig, A.R.

    1996-05-01

    A personal computer based system was developed for on-line monitoring, signal processing and display of important parameters of the Pakistan Reactor-1. The system was designed for assistance to both reactor operator and users. It performs three main functions. The first is the centralized radiation monitoring in and around the reactor building. The computer acquires signals from radiation monitoring channels and continuously displays them on distributed monitors. Trend monitoring and alarm generation is also done. In case of any abnormal condition the radiation level data is automatically stored in computer memory for detailed off-line analysis. In the second part the computer does the performance testing of nuclear instrumentation channels by signal statistical analysis and generates alarm in case the channel standard deviation error exceeds the permissible error. Mean values of important nuclear signals are also displayed on distributed monitors as a part of reactor safety parameters display system. The third function is on-line computation of reactor physics parameters of the core which are important from operational and safety point-of-view. The signals from radiation protection system and nuclear instrumentation channels in the reactor were interfaced with the computer for this purpose. The development work was done under an IAEA research contract as a part of coordinated research programme. (author) 12 figs

  3. Development of a central PC-based system for reactor signal monitoring and analysis

    International Nuclear Information System (INIS)

    Karim, A.; Ansari, S.A.; Rauf Baig, A.

    1998-01-01

    A personal computer based system was developed for on-line monitoring, signal processing and display of important reactor parameters of the Pakistan Research Reactor-1. The system was designed for assistance to both reactor operator and users. It performs three main functions. The first is the centralized radiation monitoring in and around the reactor building. The computer acquires signals from radiation monitoring channels and continuously displays them on distributed monitors. Trend monitoring and alarm generation is also done. In case of any abnormal condition the radiation level data is automatically stored in computer memory for detailed off-line analysis. In the second part the computer does the performance testing of nuclear instrumentation channels by signal statistical analysis, and generates alarm in case the channel standard deviation error exceeds the permissible error. Mean values of important nuclear signals are also displayed on distributed monitors as a part of reactor safety parameters display system. The third function is on-line computation of reactor physics parameters of the core which are important from operational and safety points-of-view. The signals from radiation protection system and nuclear instrumentation channels in the reactor were interfaced with the computer for this purpose. The development work was done under an IAEA research contract as a part of coordinated research programme. (author)

  4. Incidence and mechanism of central pontine myelinolysis based on analysis of MRI images and risk factors

    International Nuclear Information System (INIS)

    Kondo, Masato

    2000-01-01

    In this study, the incidence of central pontine myelinolysis (CPM)-like lesions on MRI images was studied in 1917 subjects, 1,500 of which were psychiatric patients and 417 were patients attending a brain health examination. The CPM-like lesions were first classified into four groups based on the characteristics of their MRI images: group 1 showed symmetrical lesions on both T1 low and T2 high images and were considered to be typical CPM; group 2 showed symmetrical high intensity lesions only on T2 images; group 3 had asymmetrical lesions only on T2 images; and group 4 had asymmetrical lesions on both T1 low and T2 high images. Furthermore, the relationships of each group with particular risk factors, such as alcoholism, hypertension, hyperlipidemia were statistically analysed. The cause of CPM-like features in the MRI images were discussed. Among our subjects, the incidence of CPM-like lesions was 3.8%, and that of group 1 was 1.2%. Significant correlations between group 1 and alcoholism, and group 3 and 4 with brain ischemic lesions were observed. A previous hypothesis that group 2 may be a premature state of CPM is not supported by our results. (author)

  5. The Contribution of a Central Pattern Generator in a Reflex-Based Neuromuscular Model

    Directory of Open Access Journals (Sweden)

    Florin eDzeladini

    2014-06-01

    Full Text Available Although the concept of central pattern generators (CPGs controlling locomotion in vertebrates is widely accepted, the presence of specialized CPGs in human locomotion is still a matter of debate. An interesting numerical model developed in the 90s' demonstrated the important role CPGs could play in human locomotion, both in terms of stability against perturbations, and in terms of speed control. Recently, a reflex-based neuro-musculo-skeletal model has been proposed, showing a level of stability to perturbations similar to the previous model, without any CPG components. Although exhibiting striking similarities with human gaits, the lack of CPG makes the control of speed/step length in the model difficult. In this paper, we hypothesize that a CPG component will offer a meaningful way of controlling the locomotion speed. After introducing the CPG component in the reflex model, and taking advantage of the resulting properties, a simple model for gait modulation is presented.The results highlight the advantages that a feedforward component can have in terms of gait modulation.

  6. Characteristics and composition of atmospheric aerosols in Phimai, central Thailand during BASE-ASIA

    Science.gov (United States)

    Li, Can; Tsay, Si-Chee; Hsu, N. Christina; Kim, Jin Young; Howell, Steven G.; Huebert, Barry J.; Ji, Qiang; Jeong, Myeong-Jae; Wang, Sheng-Hsiang; Hansell, Richard A.; Bell, Shaun W.

    2013-10-01

    Comprehensive measurements of atmospheric aerosols were made in Phimai, central Thailand (15.183°N, 102.565°E, elevation: 206 m) during the BASE-ASIA field experiment from late February to early May in 2006. The observed aerosol loading was sizable for this rural site (mean aerosol scattering: 108 ± 64 Mm-1; absorption: 15 ± 8 Mm-1; PM10 concentration: 33 ± 17 μg m-3), and dominated by submicron particles. Major aerosol compounds included carbonaceous (OC: 9.5 ± 3.6 μg m-3; EC: 2.0 ± 2.3 μg m-3) and secondary species (SO42-: 6.4 ± 3.7 μg m-3, NH4+: 2.2 ± 1.3 μg m-3). While the site was seldom under the direct influence of large forest fires to its north, agricultural fires were ubiquitous during the experiment, as suggested by the substantial concentration of K+ (0.56 ± 0.33 μg m-3). Besides biomass burning, aerosols in Phimai during the experiment were also strongly influenced by industrial and vehicular emissions from the Bangkok metropolitan region and long-range transport from southern China. High humidity played an important role in determining the aerosol composition and properties in the region. Sulfate was primarily formed via aqueous phase reactions, and hygroscopic growth could enhance the aerosol light scattering by up to 60%, at the typical morning RH level of 85%. The aerosol single scattering albedo demonstrated distinct diurnal variation, ranging from 0.86 ± 0.04 in the evening to 0.92 ± 0.02 in the morning. This experiment marks the first time such comprehensive characterization of aerosols was made for rural central Thailand. Our results indicate that aerosol pollution has developed into a regional problem for northern Indochina, and may become more severe as the region's population and economy continue to grow.

  7. Political and Legal Bases of Foreign Policy Activity of the European Union in the Region of Central Asia

    Directory of Open Access Journals (Sweden)

    Turdimurat M. Tursunmuratov

    2017-10-01

    Full Text Available The author analyses the European Union’s foreign policy in Central Asia. He indicates the basic tendencies of development of the EU cooperation with the countries of Central Asian region. Further, the author analyzes the implementation of joint projects within the framework adopted by the Partnership Agreements. Based on a critical analysis, the researcher highlights a number of constraints to effective development of relations between the EU and Central Asian states. He carries out a structural analysis of conceptual documents of the European Union for the development of bilateral and multilateral relations with Central Asian countries in the region. Scientific novelty of this work lies in the systematization of stages in the evolution of relations between the European Union and the countries of Central Asia. The author divides the formation of cooperation into four main stages. The first stage of the relations between the EU and the countries of Central Asia includes conceptual framework of the legal regulatory structure of bilateral and multilateral cooperation. The second stage is characterized by the realization of a number of joint projects in the field of transport communications, democratic transformations, regional security and stability. The third stage of the relations is determined by acquiring of special geographical significance of the region of Central Asia resulting from the engagement of the International Security Assistance Force in Afghanistan in 2001. The fourth stage has begun in 2015 with the adoption of the EU Strategy for a New Partnership with Central Asia for 2017-2021. These studies serve as a basis for developing some important proposals and recommendations for the improvement of the effectiveness of cooperation between the parties.

  8. Quantification and site-specification of the support practice factor when mapping soil erosion risk associated with olive plantations in the Mediterranean island of Crete.

    Science.gov (United States)

    Karydas, Christos G; Sekuloska, Tijana; Silleos, Georgios N

    2009-02-01

    Due to inappropriate agricultural management practices, soil erosion is becoming one of the most dangerous forms of soil degradation in many olive farming areas in the Mediterranean region, leading to significant decrease of soil fertility and yield. In order to prevent further soil degradation, proper measures are necessary to be locally implemented. In this perspective, an increase in the spatial accuracy of remote sensing datasets and advanced image analysis are significant tools necessary and efficient for mapping soil erosion risk on a fine scale. In this study, the Revised Universal Soil Loss Equation (RUSLE) was implemented in the spatial domain using GIS, while a very high resolution satellite image, namely a QuickBird image, was used for deriving cover management (C) and support practice (P) factors, in order to map the risk of soil erosion in Kolymvari, a typical olive farming area in the island of Crete, Greece. The results comprised a risk map of soil erosion when P factor was taken uniform (conventional approach) and a risk map when P factor was quantified site-specifically using object-oriented image analysis. The results showed that the QuickBird image was necessary in order to achieve site-specificity of the P factor and therefore to support fine scale mapping of soil erosion risk in an olive cultivation area, such as the one of Kolymvari in Crete. Increasing the accuracy of the QB image classification will further improve the resulted soil erosion mapping.

  9. Solar thermal power stations for activities implemented jointly. The Theseus 50 MWe solar thermal power plant for the island of Crete, Greece

    Energy Technology Data Exchange (ETDEWEB)

    Brakmann, Georg [Fichtner, Stuttgart (Germany); Aringhoff, Rainer [Pilkington Solar International (United Kingdom); Cobi, Arend [PreussenElektra (Germany)

    1998-09-01

    THESEUS, the proposed commercial 50 MWe (net) Thermal Solar European Power Station for the Island of Crete is a solar hybrid plant with parabolic trough collectors and an advanced high efficiency Rankine reheat steam cycle. At the end of 1996 the DG XVII (Energy) of the European Commission has accepted the THERMIE application of the THESEUS consortium for the design phase. THESEUS reduces the required oil imports by 28 000 t/a, thereby saving the Greek economy every year 4 million ECU in foreign currency. During its 25 years technical lifetime 2.2 million tons of CO{sub 2} emissions will be avoided. Supply, construction, erection and operation of THESEUS creates 2 000 qualified employments (man-years). Because of the high manpower intensity of solar plants and their larger capital income from interest payments in contrast to the high fuel import intensity of fossil plants, THESEUS will generate larger tax revenues for Greece and for the supplier`s countries. The investment cost of THESEUS is some 135 million ECU. Even without any subsidies this would result in electricity generation cost of some 0.085 ECY/kWh, which is lower than the current average cost from the existing power plants of Crete. (author)

  10. Emulation-based comparative study of centralized and distributed control schemes for optical networks

    Science.gov (United States)

    Xin, Chunsheng; Ye, Yinghua; Dixit, Sudhir; Qiao, Chunming

    2001-07-01

    Recently there are considerable amount of research about the automatic control and provisioning in all optical networks. One of the critical issues is how to provide effective lightpath provisioning to improve network performance, such as blocking probability and decision time. Depending on the network topology, configuration, and administration policy, a distributed or centralized control scheme can be employed to manage the routing and signaling. In a distributed control scheme, each node exchanges information with other nodes, but performs routing and signaling independently from other nodes. On the other hand, in a centralized scheme, each node communicates with a central controller and the controller performs routing and signaling on behalf of all other nodes. Intuitively, the centralized scheme can obtain a lower blocking probability since the controller has the complete resource availability information. We have studied the two schemes through emulations, determined the signaling and processing overheads and quantified the conditions that favor one approach over the other.

  11. The efficacy of centralized flow rate control in 802.11-based wireless mesh networks

    KAUST Repository

    Jamshaid, K.; Ward, P.; Karsten, M.; Shihada, Basem

    2013-01-01

    predictably to congestion notification, can we enforce a desired rate allocation through a single centralized controller? The answer is not obvious because flows experience varying contention levels, and transmissions are scheduled by a node using imperfect

  12. Environmental Drivers of NDVI-Based Vegetation Phenology in Central Asia

    Directory of Open Access Journals (Sweden)

    Jahan Kariyeva

    2011-02-01

    Full Text Available Through the application and use of geospatial data, this study aimed to detect and characterize some of the key environmental drivers contributing to landscape-scale vegetation response patterns in Central Asia. The objectives of the study were to identify the variables driving the year-to-year vegetation dynamics in three regional landscapes (desert, steppe, and mountainous; and to determine if the identified environmental drivers can be used to explain the spatial-temporal variability of these spatio-temporal dynamics over time. It was posed that patterns of change in terrestrial phenology, derived from the 8 km bi-weekly time series of Normalized Difference Vegetation Index (NDVI data acquired by the Advanced Very High Resolution Radiometer (AVHRR satellites (1981–2008, can be explained through a multi-scale analysis of a suite of environmental drivers. Multiple linear stepwise regression analyses were used to test the hypotheses and address the objectives of the study. The annually computed phenological response variables or pheno-metricstime (season start, season length, and an NDVI-based productivity metric were modeled as a function of ten environmental factors relating to soil, topography, and climate. Each of the three studied regional landscapes was shown to be governed by a distinctive suite of environmental drivers. The phenological responses of the steppe landscapes were affected by the year-to-year variation in temperature regimes. The phenology of the mountainous landscapes was influenced primarily by the elevation gradient. The phenological responses of desert landscapes were demonstrated to have the greatest variability over time and seemed to be affected by soil carbon content and year-to-year variation of both temperature regimes and winter precipitation patterns. Amounts and scales of observed phenological variability over time (measured through coefficient of variation for each pheno-metrictime in each of the regional

  13. Attenuation Tomography Based on Strong Motion Data: Case Study of Central Honshu Region, Japan

    Science.gov (United States)

    Kumar, Parveen; Joshi, A.; Verma, O. P.

    2013-12-01

    Three-dimensional frequency dependent S-wave quality factor (Qβ(f)) value for the central Honshu region of Japan has been determined in this paper using an algorithm based on inversion of strong motion data. The method of inversion for determination of three-dimensional attenuation coefficients is proposed by H ashida and S himazaki (J Phys Earth. 32, 299-316, 1984) and has been used and modified by J oshi (Curr Sci. 90, 581-585, 2006; Nat Hazards. 43, 129-146, 2007) and J oshi et al. (J. Seismol. 14, 247-272, 2010). Twenty-one earthquakes digitally recorded on strong motion stations of Kik-net network have been used in this work. The magnitude of these earthquake ranges from 3.1 to 4.2 and depth ranging from 5 to 20 km, respectively. The borehole data having high signal to noise ratio and minimum site effect is used in the present work. The attenuation structure is determined by dividing the entire area into twenty-five three-dimensional blocks of uniform thickness having different frequency-dependent shear wave quality factor. Shear wave quality factor values have been determined at frequencies of 2.5, 7.0 and 10 Hz from record in a rectangular grid defined by 35.4°N to 36.4°N and 137.2°E to 138.2°E. The obtained attenuation structure is compared with the available geological features in the region and comparison shows that the obtained structure is capable of resolving important tectonic features present in the area. The proposed attenuation structure is compared with the probabilistic seismic hazard map of the region and shows that it bears some remarkable similarity in the patterns seen in seismic hazard map.

  14. Awareness and Knowledge of Glaucoma in Central India: A Hospital-Based Study.

    Science.gov (United States)

    Maharana, Prafulla K; Rai, Vaishali G; Pattebahadur, Rajesh; Singhi, Shipra; Chauhan, Ashish K

    2017-01-01

    To assess the awareness and knowledge of glaucoma among people attending the ophthalmology outpatient department at a tertiary care hospital in central India. A prospective observational study. A questionnaire-based study was conducted, involving persons aged 18 and above attending the ophthalmology outpatient department from October 2014 to September 2015. Data on awareness and knowledge of glaucoma was collected through a face-to-face interview. Fourteen hundred people participated in the study. The mean age of participants was 43 ± 15 years (range, 18-85). The study participants included 53% men and 47% women. Only 27% (n = 380/1400) of the participants were aware of glaucoma. Age, sex, and presence or type of refractive error had no impact on glaucoma awareness. Awareness level was greater in individuals with higher education levels and those belonging to an upper socioeconomic class (SEC). Multiple logistic regression analysis revealed significantly higher levels of glaucoma awareness among participants belonging to the upper 2 SECs (P = 0.05) and those educated above the high school level (P = 0.001). The most common source of awareness was close acquaintance with relatives, famly members, and friends of glaucoma patients. Awareness of glaucoma in India is low. Lack of education and lower socioeconomic status are the major risk factors for late preentation of glaucoma. Continuous presence of a low level of awareness and the same factors accounting for it warrants the need for an aggressive and refined approach to increase awareness of glaucoma to prevent glaucoma-related blindness. Copyright 2017 Asia-Pacific Academy of Ophthalmology.

  15. GAVDOS/west crete cal-val site: Over a decade calibrations for Jason series, SARAL/Altika, cryoSat-2, Sentinel-3 and HY-2 altimeter satellites

    DEFF Research Database (Denmark)

    Mertikas, Stelios; Tziavos, Ilias; Galanakis, Demitris

    This work presents and compares the latest altimeter calibration results for the Sentinel-3, Jason series, as well as the SARAL/AltiKa and the Chinese HY-2 missions, conducted at the Gavdos/Crete calibration/validation facilities. At first, the Jason altimeter calibration values will be given for...

  16. Prototyping and dissemination of ecological olive production systems : a methodology for designing and a first step towards validation and dissemination of prototype Ecological Olive Productions Systems (EOPS) in Crete

    NARCIS (Netherlands)

    Kabourakis, E.

    1996-01-01


    The olive sector in Crete, Greece, as in many other olive producing regions in Mediterranean European Union, faces agronomic, ecological and socioeconomic problems. These problems to a large extent are due to one sided ways of production aimed at maximum levels of production while

  17. Central skull base osteomyelitis as a complication of necrotizing otitis externa: Imaging findings, complications, and challenges of diagnosis

    International Nuclear Information System (INIS)

    Adams, A.; Offiah, C.

    2012-01-01

    Central skull base osteomyelitis is a rare, life-threatening complication of necrotizing or “malignant” otitis externa (NOE), which results in destruction of the skull base. The imaging appearances can be misinterpreted as malignancy but consideration of this diagnosis, both radiologically and clinically, is imperative to avoid the need for biopsy. The aim of this review is to highlight the pertinent imaging findings on computed tomography and magnetic resonance imaging as well as the potential complications of this condition.

  18. Access to facility delivery and caesarean section in north-central Liberia: a cross-sectional community-based study

    Science.gov (United States)

    Gartland, Matthew G; Taryor, Victor D; Norman, Andy M; Vermund, Sten H

    2012-01-01

    Objective Rural north-central Liberia has one of the world's highest maternal mortality ratios. We studied health facility birthing service utilisation and the motives of women seeking or not seeking facility-based care in north-central Liberia. Design Cross-sectional community-based structured interviews and health facility medical record review. Setting A regional hospital and the surrounding communities in rural north-central Liberia. Participants A convenience sample of 307 women between 15 and 49 years participated in structured interviews. 1031 deliveries performed in the regional hospital were included in the record review. Primary outcomes Delivery within a health facility and caesarean delivery rates were used as indicators of direct utilisation of care and as markers of availability of maternal health services. Results Of 280 interview respondents with a prior childbirth, only 47 (16.8%) delivered their last child in a health facility. Women who did not use formal services cited cost, sudden labour and family tradition or religion as their principal reasons for home delivery. At the regional hospital, the caesarean delivery rate was 35.5%. Conclusions There is an enormous unmet need for maternal health services in north-central Liberia. Greater outreach and referral services as well as community-based education among women, family members and traditional midwives are vital to improve the timely utilisation of care. PMID:23117566

  19. Closeness-Centrality-Based Synchronization Criteria for Complex Dynamical Networks With Interval Time-Varying Coupling Delays.

    Science.gov (United States)

    Park, Myeongjin; Lee, Seung-Hoon; Kwon, Oh-Min; Seuret, Alexandre

    2017-09-06

    This paper investigates synchronization in complex dynamical networks (CDNs) with interval time-varying delays. The CDNs are representative of systems composed of a large number of interconnected dynamical units, and for the purpose of the mathematical analysis, the leading work is to model them as graphs whose nodes represent the dynamical units. At this time, we take note of the importance of each node in networks. One way, in this paper, is that the closeness-centrality mentioned in the field of social science is grafted onto the CDNs. By constructing a suitable Lyapunov-Krasovskii functional, and utilizing some mathematical techniques, the sufficient and closeness-centrality-based conditions for synchronization stability of the networks are established in terms of linear matrix inequalities. Ultimately, the use of the closeness-centrality can be weighted with regard to not only the interconnection relation among the nodes, which was utilized in the existing works but also more information about nodes. Here, the centrality will be added as the concerned information. Moreover, to avoid the computational burden causing the nonconvex term including the square of the time-varying delay, how to deal with it is applied by estimating it to the convex term including time-varying delay. Finally, two illustrative examples are given to show the advantage of the closeness-centrality in point of the robustness on time-delay.

  20. GEODATA: Information System Based on Geospatial for Early Warning Tracking and Analysis Agricultural Plant Diseases in Central Java

    Science.gov (United States)

    Prasetyo, S. Y. J.; Agus, Y. H.; Dewi, C.; Simanjuntak, B. H.; Hartomo, K. D.

    2017-03-01

    The Government of Indonesia is currently faced with the problems of food, especially rice. It needs in large numbers that have to import from neighboring countries. Actually, the Indonesian government has the ability to produce rice to meet national needs but is still faced with the problem of pest attack rice annually increasing extent. One of the factors is that geographically Indonesia located on the migration path of world rice insect pests (called BPH or Brown Planthoppers) (Nilaparvata lugens Stal.) It leads endemic status annually. One proposed strategy to be applied is to use an early warning system based on a specific region of the main pest population. The proposed information system called GEODATA. GEODATA is Geospatial Outbreak of Disease Tracking and Analysis. The system works using a library ESSA (Exponential Smoothing - Spatial Autocorrelation) developed in previous studies in Satya Wacana Christian University. GEODATA built to meet the qualifications required surveillance device by BMKG (Indonesian Agency of Meteorology, Climatology and Geophysics’ Central Java Provinces), BPTPH (Indonesian Agency of Plant Protection and Horticulture) Central Java Provinces, BKP-KP District Boyolali, Central Java, (Indonesian Agency of Food Security and Agriculture Field Supervisor, District Boyolali, Central Java Provinces) and farmer groups. GIS GEODATA meets the needs of surveillance devices that include: (1) mapping of the disease, (2) analysis of the dynamics of the disease, and (3) prediction of attacks / disease outbreaks in a particular region. GIS GEODATA is currently under implementation in the laboratory field observations of plant pest in Central Java province, Indonesia.

  1. Branch-Based Centralized Data Collection for Smart Grids Using Wireless Sensor Networks

    OpenAIRE

    Kwangsoo Kim; Seong-il Jin

    2015-01-01

    A smart grid is one of the most important applications in smart cities. In a smart grid, a smart meter acts as a sensor node in a sensor network, and a central device collects power usage from every smart meter. This paper focuses on a centralized data collection problem of how to collect every power usage from every meter without collisions in an environment in which the time synchronization among smart meters is not guaranteed. To solve the problem, we divide a tree that a sensor network co...

  2. Mediterranean megaturbidite triggered by the AD 365 Crete earthquake and tsunami

    Science.gov (United States)

    Polonia, Alina; Bonatti, Enrico; Camerlenghi, Angelo; Lucchi, Renata Giulia; Panieri, Giuliana; Gasperini, Luca

    2013-01-01

    Historian Ammianus Marcellinus documented the devastating effects of a tsunami hitting Alexandria, Egypt, on July 21, AD 365. "The solidity of the earth was made to shake … and the sea was driven away. The waters returning when least expected killed many thousands by drowning. Huge ships… perched on the roofs of houses… hurled miles from the shore….”. Other settlements around the Mediterranean were hit at roughly the same time. This scenario is similar to that of the recent Sumatra and Tohoku tsunamis. Based on geophysical surveys and sediment cores from the Ionian Sea we show that the 20–25 m thick megaturbidite known in the literature as Homogenite/Augias was triggered not by the Santorini caldera collapse but by the 365 AD Cretan earthquake/tsunami. An older similar megaturbidite was deposited after 14.590 ± 80 yr BP, implying a large recurrence time of such extreme sedimentary events in the Mediterranean Sea. PMID:23412517

  3. Data bases for forest inventory in the North-Central Region.

    Science.gov (United States)

    Jerold T. Hahn; Mark H. Hansen

    1985-01-01

    Describes the data collected by the Forest Inventory and Analysis (FIA) Research Work Unit at the North Central Forest Experiment Station. Explains how interested parties may obtain information from the databases either through direct access or by special requests to the FIA database manager.

  4. Civil society in modern Russia: formation and development (based on Central Federal District’s materials

    Directory of Open Access Journals (Sweden)

    L. A. Bespalaya

    2015-01-01

    Full Text Available The article considers the problem of formation and development of civil society in contemporary Russia as an example of the Central Federal District. The author defines the necessary social, economic, political and cultural conditions for the successful development of civil society in our country.

  5. Ecological and economic impacts of gorilla-based tourism in Dzanga-Sangha, Central African Republic

    NARCIS (Netherlands)

    Blom, A.

    2001-01-01

    This thesis investigates the potential role of tourism in the funding of protected area management in the Congo Basin. An assessment of the protected areas and gazetted forests of the Central African Republic (CAR) showed that only about one third of the protected areas is more or less

  6. Channel utilization based energy efficient RoF centralized enterprise WLAN

    NARCIS (Netherlands)

    DebBarma, D.; Wang, Q.; Chetan, B.M.; Niemegeers, I.; Heemstra De Groot, S.M.

    2016-01-01

    Centralized Enterprise WLAN (CE-WLAN) encompassing supernumerary access points (APs) are being used to provide capacity to indoor environments. The approach of over dimensioned deployment of APs to meet the capacity needs of users at critical time periods are advocated with little concern towards

  7. Centralized optical-frequency-comb-based RF carrier generator for DWDM fiber-wireless access systems

    DEFF Research Database (Denmark)

    Pang, Xiaodan; Beltran, Marta; Sanchez, Jose

    2014-01-01

    In this paper, we report on a gigabit capacity fiber-wireless system that enables smooth integration between high-speed wireless networks and dense wavelength-division-multiplexing (DWDM) access networks. By employing a centralized optical frequency comb, both the wireline and the wireless services...

  8. The Design and Implementation of the Remote Centralized-Monitoring System of Well-Control Equipment Based on RFID Technique

    Directory of Open Access Journals (Sweden)

    Luo Bin

    2017-01-01

    Full Text Available At present, in domestic for the management of well control equipment continue to the traditional way of nameplates identifies and paper-based registration, there are many issues like the separation of data information of device, easy lose, difficult query, confused management and many other problems, which will make the problem device into the well field, and then resulting in well control runaway drilling accident. To solve the above problems, this paper put forward to the integrated remote centralized-monitoring management mode of the well-control equipment. Taking the advantages of IOT technology, adopting the RFID technology, and combining with the remote transmission, this paper designs the remote centralized-monitoring system of well-control equipment based on RFID, which realizes the intelligent management of well-control equipment and meets the actual demand of the well-control equipment safe use and timely scheduling, and it has the ability of field application.

  9. Potential of stem cell based therapy and tissue engineering in the regeneration of the central nervous system

    International Nuclear Information System (INIS)

    An Yihua; Tsang, Kent K S; Zhang Han

    2006-01-01

    The insufficiency of self-repair and regeneration of the central nervous system (CNS) leads to difficulty of rehabilitation of the injured brain. In the past few decades, the significant progress in cell therapy and tissue engineering has contributed to the functional recovery of the CNS to a great extent. The present review focuses on the potential role of stem cell based therapy and tissue engineering in the regeneration of the CNS. (topical review)

  10. Mobile and cloud based systems proposal for a centralized management of educational institutions

    Directory of Open Access Journals (Sweden)

    Leandro Medeiros de Almeida Machado

    2017-06-01

    Full Text Available The computational technological efforts towards a centralized data storage and processing have contributed to provide more sustainable solutions under the environmental, administrative and business perspectives. However, it is not yet worldwide adopted by public institutions, specially, in the Brazilian educational systems, where these technological models are still under constant discussions and development. In this sense, this work presents a brief survey about cloud and mobile integrated technologies and their possible contributions to support a centralized data management in educational systems, relating improvements in governance, data security, mobility, economic viability and environmental impact. Therefore, this work also present a list of already free and private technologies and their advantages and disadvantages in the Brazilian scenario. In this sense, the herein technological aspects considers the integration between cloud and mobile technologies as essential alternative to suppress the online requirements, which a limitation for a large number of public institutions that have problems to be effectively connected on the Internet.

  11. Mineral Deposit Data for Epigenetic Base- and Precious-metal and Uranium-thorium Deposits in South-central and Southwestern Montana and Southern and Central Idaho

    Science.gov (United States)

    Klein, T.L.

    2004-01-01

    Metal deposits spatially associated with the Cretaceous Boulder and Idaho batholiths of southwestern Montana and southern and central Idaho have been exploited since the early 1860s. Au was first discovered in placer deposits; exploitation of vein deposits in bedrock soon followed. In 1865, high-grade Ag vein deposits were discovered and remained economically important until the 1890s. Early high-grade deposits of Au, Ag and Pb were found in the weathered portions of the veins systems. As mining progressed to deeper levels, Ag and Pb grades diminished. Exploration for and development of these vein deposits in this area have continued until the present. A majority of these base- and precious-metal vein deposits are classified as polymetallic veins (PMV) and polymetallic carbonate-replacement (PMR) deposits in this compilation. Porphyry Cu and Mo, epithermal (Au, Ag, Hg and Sb), base- and precious-metal and W skarn, W vein, and U and Th vein deposits are also common in this area. The world-class Butte Cu porphyry and the Butte high-sulfidation Cu vein deposits are in this study area. PMV and PMR deposits are the most numerous in the region and constitute about 85% of the deposit records compiled. Several types of syngenetic/diagenetic sulfide mineral deposits in rocks of the Belt Supergroup or their equivalents are common in the region and they have been the source of a substantial metal production over the last century. These syngenetic deposits and their metamorphosed/structurally remobilized equivalents were not included in this database; therefore, deposits in the Idaho portion of the Coeur d'Alene district and the Idaho Cobalt belt, for example, have not been included because many of them are believed to be of this type.

  12. Regulating the grid-based energies in Central and Eastern Europe: models, status, issues

    International Nuclear Information System (INIS)

    Brendow, K.

    2000-01-01

    As the electricity, gas and heat industries of the economies in transition move towards more market-oriented frameworks, regulators are established to secure fair competition, protection of the customers and a minimum of public service. The paper describes the various models used or contemplated in the autumn of 2000 in central and eastern Europe and identifies fifteen issues, some falling under the competence of governments, others challenging the regulators, again others relating to international co-operation. (author)

  13. A comparison of attitudes toward lesbians and gay men among students of helping professions in Crete, Greece: the cases of social work, psychology, medicine, and nursing.

    Science.gov (United States)

    Papadaki, Vasileia; Plotnikof, Kyriaki; Gioumidou, Meropi; Zisimou, Vasiliki; Papadaki, Eleni

    2015-01-01

    This study investigated the attitudes toward lesbians and gay men among social work, psychology, medical, and nursing students in Crete, Greece, using Herek's ATLG scale. No respondents held completely heterosexist attitudes; only 1.6% held completely non-heterosexist attitudes. The 44.96 total ATLG score indicates a slightly positive attitude toward lesbians and gay men. Psychology students scored higher than all others on positive attitudes, followed by social work students, medical students, and nursing students. Gender, having lesbian or gay acquaintances or friends, and religiosity were significant factors influencing students' attitudes, while no impact on attitudes due to the effects of higher education could be discerned. Implications for curriculum design and teaching methods are discussed.

  14. New Structural Interpretation of the Central Confusion Range, Western Utah, Based On Balanced Cross Sections

    Science.gov (United States)

    Yezerski, D.; Greene, D. C.

    2009-12-01

    The Confusion Range is a topographically low mountain range in the Basin and Range of west-central Utah, located east of and in the hanging wall of the Snake Range core complex. Previous workers have used a gravity sliding model to interpret the Confusion Range as a large structural trough or synclinorium (e.g. Hose, 1977). Based on existing mapping (Hose, 1965; Hintze, 1974) and new field data, we use balanced and restored cross sections to reinterpret the structure of the Confusion Range as an east-vergent fold-and-thrust belt formed during the Sevier Orogeny. The Confusion Range consists of Cambro-Ordovician through Triassic strata, with predominantly thick-bedded, competent carbonate rocks in the lower Paleozoic (lPz) section and incompetent shales and thin-bedded carbonates in the upper Paleozoic (uPz) section. The contrasting mechanical behavior of these stratigraphic sections results in faulted folds within uPz carbonates above detachments in shale-rich units, deforming in response to ramp-flat thrust faulting of the underlying lPz units. East of the axis of the Conger Mountain (Mtn) syncline, we attribute the increase in structural elevation of lPz rocks to a subsurface thrust sheet consisting of lPz strata that advanced eastward via a high-angle ramp from a lower detachment in the Kanosh Shale to an upper detachment in the Pilot Shale. The doubling of lPz strata that resulted continues through the eastern Confusion Range where a series of small-displacement thrust faults comprising the Kings Canyon thrust system gently tilt strata to the west. In the Conger Range, west of the Conger Mtn syncline, our analysis focuses on reinterpreting the geometrically unlikely folding depicted in previous cross sections as more admissible, fault-cored, asymmetric, detached folding. In our interpretation, resistance created by a steeply-dipping thrust ramp in the lPz section west of Conger Mtn resulted in folding of uPz strata into an east-vergent anticline. Continued east

  15. Community based ecological restoration of peatland in Central Mongolia for climate change mitigation and adaptation

    Science.gov (United States)

    Minayeva, Tatiana; Chultem, Dugarjav; Grootjans, Ab; Yamkhin, Jambaljav; Sirin, Andrey; Suvorov, Gennady; Batdorj, Oyunbileg; Tsamba, Batdorj

    2017-04-01

    Peatlands cover almost 2 % of Mongolia. They play crucial role in regulation of key natural processes in ecosystems and provide unique resources to maintain traditional way of life and livelihoods of herders. During the last decades, Mongolian peatlands severely degraded both due to the climate related events and due to overgrazing. The peat degradation causes significant losses of carbon store, GHG emissions and is followed by changes in water balance and water composition. The issue arises if such a type of ecosystems as peatlands could be a subject for ecosystem restoration in this arid and subhumid climate. Could it be considered as measure for climate change mitigation and adaptation? With funding opportunities from the Asian Development Bank a pilot project for peatland restoration had been launched in 2016 in Khashaat soum, Arkhangai aimag in Central Mongolia. The pilot aimed to merge local interests of herders with global targets of climate change mitigation. The following questions are addressed: what are the losses of natural functions and ecosystem services of peatland; what are expectations and demands of local communities and incentives for their involvement; how should and could look the target ecosystem; what are the technical solutions in order to achieve the target ecosystem characteristics; and what are the parameters for monitoring to assess the success of the project? The comprehensive baseline study addressed both natural and social aspects. The conclusions are: most of peat in the study area had been mineralised and has turned to organic rich soil with carbon content between 20 to 40 %, the key sources of water - small springs - are partly destroyed by cattle; the permafrost disappeared in this area and could not be the subject for restoration; local herders understand the value of peatland as water source and had carried out some voluntary activities for water storage and regulation such as dam construction; nevertheless there is no

  16. El Greco's Italian paintings (1560-76) based on Bible texts | Maré ...

    African Journals Online (AJOL)

    The purpose of this article is to interpret a selection of El Greco's Italian paintings (1560-1576) based on Bible texts in which ideas current during the Catholic Counter-Reformation are symbolised. At the age of nineteen El Greco, who was born in Crete in 1541 and was initially an icon painter in the Byzantine tradition, went ...

  17. Dietary and other lifestyle correlates of serum folate concentrations in a healthy adult population in Crete, Greece: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Scott John M

    2006-02-01

    Full Text Available Abstract Background Folate has emerged as a key nutrient for optimising health. Impaired folate status has been identified as a risk factor for cardiovascular disease, various types of cancers, and neurocognitive disorders. The study aimed at examining the distribution and determinants of serum folate concentrations in a healthy adult population in Crete, Greece. Methods A cross-sectional sample of 486 healthy adults (250 men, 236 women aged 39 ± 14 years, personnel of the Medical School and the University Hospital of Crete in Greece, was examined. Serum folate and vitamin B12 concentrations were measured by microbiological assay, and total homocysteine was determined fluorometrically and by high-pressure liquid chromatography. Lifestyle questionnaires were completed, and nutrient intakes and food consumption were assessed by 24-h dietary recalls. Multivariate analyses were performed using SPSS v10.1. Results The geometric mean (95% confidence interval concentrations of serum folate were 15.6 μmol/l (14.6–16.8 in men and 19.2 μmol/l (17.9–20.7 in women (p 1, and B6 were positively associated with serum folate. Consumption of potatoes, legumes, fruits, and vegetables were favourably related to the serum folate status. Conclusion Serum folate concentrations were associated with various demographic, lifestyle and dietary factors in healthy Cretan adults. Large-scale epidemiological studies should be conducted within the general Greek adult population to assess the prevalence of impaired folate status and further examine associations with dietary patterns and chronic disease risk. Considering the importance of folate in health maintenance, it is important to increase the public's awareness of modifiable lifestyle patterns and diet and tobacco use in particular, which may be associated with improved folate status.

  18. Teachers' professional development in a community: A study of the central actors, their networks and web-based learning

    Directory of Open Access Journals (Sweden)

    Jiri Lallimo

    2008-07-01

    Full Text Available The goal of this article was to study teachers' professional development related to web-based learning in the context of the teacher community. The object was to learn in what kind of networks teachers share the knowledge of web-based learning and what are the factors in the community that support or challenge teachers professional development of web-based learning. The findings of the study revealed that there are teachers who are especially active, called the central actors in this study, in the teacher community who collaborate and share knowledge of web-based learning. These central actors share both technical and pedagogical knowledge of web-based learning in networks that include both internal and external relations in the community and involve people, artefacts and a variety of media. Furthermore, the central actors appear to bridge different fields of teaching expertise in their community.According to the central actors' experiences the important factors that support teachers' professional development of web-based learning in the community are; the possibility to learn from colleagues and from everyday working practices, an emotionally safe atmosphere, the leader's personal support and community-level commitment. Also, the flexibility in work planning, challenging pupils, shared lessons with colleagues, training events in an authentic work environment and colleagues' professionalism are considered meaningful for professional development. As challenges, the knowledge sharing of web-based learning in the community needs mutual interests, transactive memory, time and facilities, peer support, a safe atmosphere and meaningful pedagogical practices.On the basis of the findings of the study it is suggested that by intensive collaboration related to web-based learning it may be possible to break the boundaries of individual teachership and create such sociocultural activities which support collaborative professional development in the teacher

  19. STRATEGIC PURCHASING IN A PROJECT- BASED COMPANY – TO CENTRALIZE OR DECENTRALIZE

    Directory of Open Access Journals (Sweden)

    Eva Donociková

    2014-03-01

    Full Text Available Organizations all lie on a spectrum, at one end of which are firms with complete centralization of purchasing, and at the other end are firms with complete decentralization. Most firms lie somewhere between the two extremes, and we have already mentioned the most common model that has certain decisions centralized (perhaps strategy design, selection of suppliers, purchasing of major capital equipment, training, co-ordination, communications, etc. and bulk of purchasing devolved to local buyers. There are many variations on the type of activities that are either centralized or decentralized. In the last 12 years purchasing has noticed two radical changes in the majority of facilities. First change was the reverse of supplier – customer relationships where the role of purchasers changed from persuading and begging the suppliers to ever deliver, preferably with minimum delay (for fixed prices, to standard purchase activities where the purchaser can choose from many suppliers and negotiate prices with vendors to achieve the best conditions for his buyer. The second change was the establishing of a modern IT system that made purchasing activities more effective, more automatic and transparent to a considerable extent. It is good to realize whether all changes have led to improvement or whether these changes have caused a stop or a slowdown of the project purchasing – whether it is possible or even necessary to take into account global as well as local suppliers or to combine them. This Case Study demonstrates how a project - managed organization could look like, where it is necessary to take into account customer´s wishes and benefit.

  20. Turbine model for the Laguna Verde nucleo electric central based in the RELAP code

    International Nuclear Information System (INIS)

    Cortes M, F.S.; Ramos P, J.C.; Salazar S, E.; Chavez M, C.

    2003-01-01

    The Nuclear Power stations as Laguna Verde occupy at the present time a place every time but important as non pollutant alternative, economic and trusty to generate electricity. It is for it that the Group of Nuclear Engineering of the Engineering Faculty (GrlNFI) of the National Autonomous University of Mexico (UNAM) it develops investigation projects applied to Nuclear Centrals. One of the projects in process is the development of a Classroom simulator, which it can configures to consent to diverse models of nuclear systems with training purposes in normal operation, or, to consent to specialized nuclear codes for the analysis of transitory events and have a severe accident. This work describes the development, implementation and it proves of a simplified model of the Main turbine to be integrated to the group of models of the Classroom simulator. It is part of the current effort of GrlNFI guided to obtain a representation of all the dynamic models necessary to simulate the Plant Balance of the Laguna Verde Central. It is included the development of the unfolding graphic which represent the modeling of the Main turbine, and of the control interface that allows the user to manipulate in simple way, direct and interactive this device during the training or the analysis. With this work it is wanted to contribute to the training of new technicians and to support the operation personnel of the Centrals. Also, the developed infrastructure is guided to contribute in the design and analysis of new Nuclear Power stations with the contribution of new computational tools for the visualization, simulation and process control. (Author)

  1. Ocular biometry and central corneal thickness in children: a hospital-based study

    Directory of Open Access Journals (Sweden)

    Adem Gul

    2014-06-01

    Full Text Available Objetivo: Investigar a distribuição do comprimento axial, profundidade da câmara anterior, espessura do cristalino, profundidade da câmara vítrea e espessura corneal central em crianças em diferentes faixas etárias. Métodos: Foram estudados 364 olhos de 182 crianças entre 1 e 12 anos de idade. O comprimento axial, a profundidade da câmara anterior , a espessura do cristalino e a profundidade da câmara vítrea foram medidos por biometria ultrassônica. A espessura corneal central foi medida por paquimetria ultrassônica em todas as crianças. Resultados: A idade média foi de 6,54 ± 3,42 anos. O comprimento axial foi 20,95 mm no grupo de 1-2 anos de idade e 22,95 mm no grupo de 11-12 anos de idade. A espessura corneal central foi 556 µm no grupo de 1-2 anos de idade e 555 µm no grupo de 11-12 anos de idade. A profundidade da câmara anterior média e profundidade da câmara vítrea aumentou com a idade (3,06 mm a 3,44 mm de profundidade da câmara anterior, 13,75 mm a 15,99 mm de profundidade da câmara vítrea e da espessura do cristalino diminuiu com o aumento da idade (3,67 mm a 3,51 mm. Conclusões: Em nosso estudo, os valores do comprimento axial aumentou com a idade e atingiu os níveis adultos aos 9-10 anos de idade. A espessura do cristalino diminuiu gradualmente até os 12 anos de idade. As medições de espessura corneal central não seguiu um algoritmo linear.

  2. Imaging findings of central nervous system infections. Case-based review

    International Nuclear Information System (INIS)

    Yagishita, Akira

    2008-01-01

    Prompt detection and an accurate diagnosis of central nervous system (CNS) infections are important because most of these disorders are readily treatable. Imaging plays a crucial role in the diagnosis of the disorders. Infections of CNS pose a worldwide public health problem. Global scale transportation means that disorders once relatively confined to certain geographic areas are now readily ''outside the window'' of practicing radiologists everywhere. Therefore, we, neuroradiologists are in the need of studying foreign infectious diseases, such as West Nile fever, enterovirus poliomyelitis, etc. (author)

  3. Maximum principle and convergence of central schemes based on slope limiters

    KAUST Repository

    Mehmetoglu, Orhan; Popov, Bojan

    2012-01-01

    A maximum principle and convergence of second order central schemes is proven for scalar conservation laws in dimension one. It is well known that to establish a maximum principle a nonlinear piecewise linear reconstruction is needed and a typical choice is the minmod limiter. Unfortunately, this implies that the scheme uses a first order reconstruction at local extrema. The novelty here is that we allow local nonlinear reconstructions which do not reduce to first order at local extrema and still prove maximum principle and convergence. © 2011 American Mathematical Society.

  4. Headset Bluetooth and cell phone based continuous central body temperature measurement system.

    Science.gov (United States)

    Sanches, J Miguel; Pereira, Bruno; Paiva, Teresa

    2010-01-01

    The accurate measure of the central temperature is a very important physiologic indicator in several clinical applications, namely, in the characterization and diagnosis of sleep disorders. In this paper a simple system is described to continuously measure the body temperature at the ear. An electronic temperature sensor is coupled to the microphone of a common commercial auricular Bluetooth device that sends the temperature measurements to a mobile phone to which is paired. The measurements are stored at the mobile phone and periodically sent to a medical facility by email or SMS (short messaging service).

  5. Structures based on semi-degradable biomaterials for neural regeneration in the central nervous system

    OpenAIRE

    Perez Garnes, Manuel

    2015-01-01

    Se pretende obtener un material semibiodegradable basado en ácido hialurónico químicamente enlazado a cadenas de polímeros acrílicos. Los hidrogeles de ácido hialurónico presentan en general buenas características para su utilización en regeneración del sistema nervioso central: es biodegradable, es un componente importante del tejido neural, sus propiedades mecánicas son semejantes a las del tejido cerebral, promueve la formación de nuevos capilares (angiogénesis), y limita la inflamación. C...

  6. When should I attempt my centrally administered summative assessments in the RANZCP competency-based training program?

    Science.gov (United States)

    Kealy-Bateman, Warren; Kotze, Beth; Lampe, Lisa

    2016-12-01

    To provide information relevant to decision-making around the timing of attempting the centrally administered summative assessments in the Royal Australian and New Zealand College of Psychiatrists (RANZCP) 2012 Fellowship Program. We consider the new Competency-Based Fellowship Program of the RANZCP and its underlying philosophy, the trainee trajectory within the program and the role of the supervisor. The relationship between workplace-based and external assessments is discussed. The timing of attempting centrally administered summative assessments is considered within the pedagogical framework of medical competencies development. Although successful completion of all the centrally administered summative assessments requires demonstration of a junior consultant standard of competency, the timing at which this standard will most commonly be achieved is likely to vary from assessment to assessment. There are disadvantages attendant upon prematurely attempting assessments, and trainees are advised to carefully consider the requirements of each assessment and match this against their current level of knowledge and skills. Trainees and supervisors need to be clear about the competencies required for each of the external assessments and match this against the trainee's current competencies to assist in decision-making about the timing of assessments and planning for future learning. © The Royal Australian and New Zealand College of Psychiatrists 2016.

  7. Structural changes of central white matter tracts in Kennedy's disease - a diffusion tensor imaging and voxel-based morphometry study.

    Science.gov (United States)

    Pieper, C C; Konrad, C; Sommer, J; Teismann, I; Schiffbauer, H

    2013-05-01

    Spinobulbar muscular atrophy [Kennedy's disease (KD)] is a rare X-linked neurodegenerative disorder of mainly spinal and bulbar motoneurons. Recent studies suggest a multisystem character of this disease. The aim of this study was to identify and characterize structural changes of gray (GM) and white matter (WM) in the central nervous system. Whole-brain-based voxel-based morphometry (VBM) and diffusion tensor imaging (DTI) analyses were applied to MRI data of eight genetically proven patients with KD and compared with 16 healthy age-matched controls. Diffusion tensor imaging analysis showed not only decreased fractional anisotropy (FA) values in the brainstem, but also widespread changes in central WM tracts, whereas VBM analysis of the WM showed alterations primarily in the brainstem and cerebellum. There were no changes in GM volume. The FA value decrease in the brainstem correlated with the disease duration. Diffusion tensor imaging analysis revealed subtle changes of central WM tract integrity, while GM and WM volume remained unaffected. In our patient sample, KD had more extended effects than previously reported. These changes could either be attributed primarily to neurodegeneration or reflect secondary plastic changes due to atrophy of lower motor neurons and reorganization of cortical structures. © 2012 John Wiley & Sons A/S.

  8. The Discriminative validity of "nociceptive," "peripheral neuropathic," and "central sensitization" as mechanisms-based classifications of musculoskeletal pain.

    LENUS (Irish Health Repository)

    Smart, Keith M

    2012-02-01

    OBJECTIVES: Empirical evidence of discriminative validity is required to justify the use of mechanisms-based classifications of musculoskeletal pain in clinical practice. The purpose of this study was to evaluate the discriminative validity of mechanisms-based classifications of pain by identifying discriminatory clusters of clinical criteria predictive of "nociceptive," "peripheral neuropathic," and "central sensitization" pain in patients with low back (+\\/- leg) pain disorders. METHODS: This study was a cross-sectional, between-patients design using the extreme-groups method. Four hundred sixty-four patients with low back (+\\/- leg) pain were assessed using a standardized assessment protocol. After each assessment, patients\\' pain was assigned a mechanisms-based classification. Clinicians then completed a clinical criteria checklist indicating the presence\\/absence of various clinical criteria. RESULTS: Multivariate analyses using binary logistic regression with Bayesian model averaging identified a discriminative cluster of 7, 3, and 4 symptoms and signs predictive of a dominance of "nociceptive," "peripheral neuropathic," and "central sensitization" pain, respectively. Each cluster was found to have high levels of classification accuracy (sensitivity, specificity, positive\\/negative predictive values, positive\\/negative likelihood ratios). DISCUSSION: By identifying a discriminatory cluster of symptoms and signs predictive of "nociceptive," "peripheral neuropathic," and "central" pain, this study provides some preliminary discriminative validity evidence for mechanisms-based classifications of musculoskeletal pain. Classification system validation requires the accumulation of validity evidence before their use in clinical practice can be recommended. Further studies are required to evaluate the construct and criterion validity of mechanisms-based classifications of musculoskeletal pain.

  9. Synthesis and in vitro transfection efficiency of spermine-based cationic lipids with different central core structures and lipophilic tails.

    Science.gov (United States)

    Niyomtham, Nattisa; Apiratikul, Nuttapon; Suksen, Kanoknetr; Opanasopit, Praneet; Yingyongnarongkul, Boon-Ek

    2015-02-01

    Twelve spermine-based cationic lipids with four different central core structures (di(oxyethyl)amino, di(oxyethyl)amino carboxy, 3-amino-1,2-dioxypropyl and 2-amino-1,3-dioxypropyl) and three hydrophobic tails (lauric acid, myristic acid and palmitic acid) were synthesized. The liposomes containing lipids and DOPE showed moderate to good in vitro DNA delivery into HeLa cells. GFP expression experiments revealed that liposomes composed of lipids with 3-amino-1,2-dioxypropyl as a central core structure exhibited highest transfection efficiency under serum-free condition. Whereas, lipid with 2-amino-1,3-dioxypropyl core structure showed highest transfection under 10% serum condition. Moreover, the liposomes and lipoplexes composted of these cationic lipids exhibited low cytotoxicity. Copyright © 2015. Published by Elsevier Ltd.

  10. Conservation Action Based on Threatened Species Capture Taxonomic and Phylogenetic Richness in Breeding and Wintering Populations of Central Asian Birds

    Science.gov (United States)

    Schweizer, Manuel; Ayé, Raffael; Kashkarov, Roman; Roth, Tobias

    2014-01-01

    Although phylogenetic diversity has been suggested to be relevant from a conservation point of view, its role is still limited in applied nature conservation. Recently, the practice of investing conservation resources based on threatened species was identified as a reason for the slow integration of phylogenetic diversity in nature conservation planning. One of the main arguments is based on the observation that threatened species are not evenly distributed over the phylogenetic tree. However this argument seems to dismiss the fact that conservation action is a spatially explicit process, and even if threatened species are not evenly distributed over the phylogenetic tree, the occurrence of threatened species could still indicate areas with above average phylogenetic diversity and consequently could protect phylogenetic diversity. Here we aim to study the selection of important bird areas in Central Asia, which were nominated largely based on the presence of threatened bird species. We show that although threatened species occurring in Central Asia do not capture phylogenetically more distinct species than expected by chance, the current spatially explicit conservation approach of selecting important bird areas covers above average taxonomic and phylogenetic diversity of breeding and wintering birds. We conclude that the spatially explicit processes of conservation actions need to be considered in the current discussion of whether new prioritization methods are needed to complement conservation action based on threatened species. PMID:25337861

  11. Low-resolution expression recognition based on central oblique average CS-LBP with adaptive threshold

    Science.gov (United States)

    Han, Sheng; Xi, Shi-qiong; Geng, Wei-dong

    2017-11-01

    In order to solve the problem of low recognition rate of traditional feature extraction operators under low-resolution images, a novel algorithm of expression recognition is proposed, named central oblique average center-symmetric local binary pattern (CS-LBP) with adaptive threshold (ATCS-LBP). Firstly, the features of face images can be extracted by the proposed operator after pretreatment. Secondly, the obtained feature image is divided into blocks. Thirdly, the histogram of each block is computed independently and all histograms can be connected serially to create a final feature vector. Finally, expression classification is achieved by using support vector machine (SVM) classifier. Experimental results on Japanese female facial expression (JAFFE) database show that the proposed algorithm can achieve a recognition rate of 81.9% when the resolution is as low as 16×16, which is much better than that of the traditional feature extraction operators.

  12. Identifying the Critical Links in Road Transportation Networks: Centrality-based approach utilizing structural properties

    Energy Technology Data Exchange (ETDEWEB)

    Chinthavali, Supriya [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-04-01

    Surface transportation road networks share structural properties similar to other complex networks (e.g., social networks, information networks, biological networks, and so on). This research investigates the structural properties of road networks for any possible correlation with the traffic characteristics such as link flows those determined independently. Additionally, we define a criticality index for the links of the road network that identifies the relative importance in the network. We tested our hypotheses with two sample road networks. Results show that, correlation exists between the link flows and centrality measures of a link of the road (dual graph approach is followed) and the criticality index is found to be effective for one test network to identify the vulnerable nodes.

  13. Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations.

    Science.gov (United States)

    Yoneyama, S; Yao, J; Guo, X; Fernandez-Rhodes, L; Lim, U; Boston, J; Buzková, P; Carlson, C S; Cheng, I; Cochran, B; Cooper, R; Ehret, G; Fornage, M; Gong, J; Gross, M; Gu, C C; Haessler, J; Haiman, C A; Henderson, B; Hindorff, L A; Houston, D; Irvin, M R; Jackson, R; Kuller, L; Leppert, M; Lewis, C E; Li, R; Le Marchand, L; Matise, T C; Nguyen, K-Dh; Chakravarti, A; Pankow, J S; Pankratz, N; Pooler, L; Ritchie, M D; Bien, S A; Wassel, C L; Chen, Y-D I; Taylor, K D; Allison, M; Rotter, J I; Schreiner, P J; Schumacher, F; Wilkens, L; Boerwinkle, E; Kooperberg, C; Peters, U; Buyske, S; Graff, M; North, K E

    2017-02-01

    Central adiposity measures such as waist circumference (WC) and waist-to-hip ratio (WHR) are associated with cardiometabolic disorders independently of body mass index (BMI) and are gaining clinically utility. Several studies report genetic variants associated with central adiposity, but most utilize only European ancestry populations. Understanding whether the genetic associations discovered among mainly European descendants are shared with African ancestry populations will help elucidate the biological underpinnings of abdominal fat deposition. To identify the underlying functional genetic determinants of body fat distribution, we conducted an array-wide association meta-analysis among persons of African ancestry across seven studies/consortia participating in the Population Architecture using Genomics and Epidemiology (PAGE) consortium. We used the Metabochip array, designed for fine-mapping cardiovascular-associated loci, to explore novel array-wide associations with WC and WHR among 15 945 African descendants using all and sex-stratified groups. We further interrogated 17 known WHR regions for African ancestry-specific variants. Of the 17 WHR loci, eight single-nucleotide polymorphisms (SNPs) located in four loci were replicated in the sex-combined or sex-stratified meta-analyses. Two of these eight independently associated with WHR after conditioning on the known variant in European descendants (rs12096179 in TBX15-WARS2 and rs2059092 in ADAMTS9). In the fine-mapping assessment, the putative functional region was reduced across all four loci but to varying degrees (average 40% drop in number of putative SNPs and 20% drop in genomic region). Similar to previous studies, the significant SNPs in the female-stratified analysis were stronger than the significant SNPs from the sex-combined analysis. No novel associations were detected in the array-wide analyses. Of 17 previously identified loci, four loci replicated in the African ancestry populations of this

  14. Study of attenuation structure for central Anatolia region, Turkey based on Keskin seismic array data

    Science.gov (United States)

    Semin, K. U.; Ozel, N. M.

    2011-12-01

    Central Anatolia is bounded in the north by the well-known north Anatolian fault system (NAFS) and on the south-southwest is bounded by the east Anatolian fault system (EAFS). The central area does not have major faults and acts as a single block moving westward. This region is not considered as seismically active as the NAFS or EAFS but the recent moderate-size Bala earthquakes (Ml=5.7, Ml= 5.5) on 20 and 27 December 2007 near the Tuz golu fault may be an indication of future seismic activity. In order to get a better picture of the crustal structure of this region we applied Coda Normalization method for the measurement of Qs-1 as a function of frequency for the frequencies 1.5, 3, 6, 8 Hz. 20 and 27 December 2007 Bala earthquakes (Ml magnitude 5.6 an 5.5) and their aftershocks recorded by the Keskin seismic array (International Monitoring System code BRTR) is analyzed in this study. Keskin seismic array has a small aperture circular design with 6 vertical short period and 1 broadband borehole seismometers. In addition, Multiple Lapse Time Window Analysis (MLTWA) method was applied to the data for the separation of intrinsic and scattering attenuation inm the region at the same frequencies. MLTWA method allowed a separation between the intrinsic attenuation and scattering attenuation. Preliminary results show a relatively low attenuation compared to western and eastern anatolia regions. This might be explained by the less seismicity in the region. A study of the regional and site attenuation of seismic waves of earthquakes in this area will contribute in predicting earthquake generated ground-motion and becomes vital in making decisions for earthquake regulations, building codes and to monitoring nuclear explosions.

  15. Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations

    Science.gov (United States)

    Yoneyama, Sachiko; Yao, Jie; Guo, Xiuqing; Fernandez-Rhodes, Lindsay; Lim, Unhee; Boston, Jonathan; Buzková, Petra; Carlson, Christopher S.; Cheng, Iona; Cochran, Barbara; Cooper, Richard; Ehret, Georg; Fornage, Myriam; Gong, Jian; Gross, Myron; Gu, C. Charles; Haessler, Jeff; Haiman, Christopher A.; Henderson, Brian; Hindorff, Lucia A.; Houston, Denise; Irvin, Marguerite R.; Jackson, Rebecca; Kuller, Lew; Leppert, Mark; Lewis, Cora E.; Li, Rongling; Le Marchand, Loic; Matise, Tara C.; Nguyen, Khanh-Dung H.; Chakravarti, Aravinda; Pankow, James S.; Pankratz, Nathan; Pooler, Loreall; Ritchie, Marylyn D.; Bien, Stephanie A.; Wassel, Christina L.; Chen, Yii-Der I.; Taylor, Kent D.; Allison, Matthew; Rotter, Jerome I.; Schreiner, Pamela J.; Schumacher, Fredrick; Wilkens, Lynne; Boerwinkle, Eric; Kooperberg, Charles; Peters, Ulrike; Buyske, Steven; Graff, Mariaelisa; North, Kari E.

    2016-01-01

    Background/Objectives Central adiposity measures such as waist circumference (WC) and waist-to-hip ratio (WHR) are associated with cardiometabolic disorders independently of BMI and are gaining clinically utility. Several studies report genetic variants associated with central adiposity, but most utilize only European ancestry populations. Understanding whether the genetic associations discovered among mainly European descendants are shared with African ancestry populations will help elucidate the biological underpinnings of abdominal fat deposition. Subjects/Methods To identify the underlying functional genetic determinants of body fat distribution, we conducted an array-wide association meta-analysis among persons of African ancestry across seven studies/consortia participating in the Population Architecture using Genomics and Epidemiology (PAGE) consortium. We used the Metabochip array, designed for fine mapping cardiovascular associated loci, to explore novel array-wide associations with WC and WHR among 15 945 African descendants using all and sex-stratified groups. We further interrogated 17 known WHR regions for African ancestry-specific variants. Results Of the 17 WHR loci, eight SNPs located in four loci were replicated in the sex-combined or sex-stratified meta-analyses. Two of these eight independently associated with WHR after conditioning on the known variant in European descendants (rs12096179 in TBX15-WARS2 and rs2059092 in ADAMTS9). In the fine mapping assessment, the putative functional region was reduced across all four loci but to varying degrees (average 40% drop in number of putative SNPs and 20% drop in genomic region). Similar to previous studies, the significant SNPs in the female stratified analysis were stronger than the significant SNPs from the sex-combined analysis. No novel associations were detected in the array-wide analyses. Conclusions Of 17 previously identified loci, four loci replicated in the African ancestry populations of

  16. Unnatural base pair systems toward the expansion of the genetic alphabet in the central dogma.

    Science.gov (United States)

    Hirao, Ichiro; Kimoto, Michiko

    2012-01-01

    Toward the expansion of the genetic alphabet of DNA, several artificial third base pairs (unnatural base pairs) have been created. Synthetic DNAs containing the unnatural base pairs can be amplified faithfully by PCR, along with the natural A-T and G-C pairs, and transcribed into RNA. The unnatural base pair systems now have high potential to open the door to next generation biotechnology. The creation of unnatural base pairs is a consequence of repeating "proof of concept" experiments. In the process, initially designed base pairs were modified to address their weak points. Some of them were artificially evolved to ones with higher efficiency and selectivity in polymerase reactions, while others were eliminated from the analysis. Here, we describe the process of unnatural base pair development, as well as the tests of their applications.

  17. Toward Understanding Dynamics in Shifting Biomes: An Individual Based Modeling Approach to Characterizing Drought and Mortality in Central Western Canada

    Science.gov (United States)

    Armstrong, A. H.; Foster, A.; Rogers, B. M.; Hogg, T.; Michaelian, M.; Shuman, J. K.; Shugart, H. H., Jr.; Goetz, S. J.

    2017-12-01

    The Arctic-Boreal zone is known be warming at an accelerated rate relative to other biomes. Persistent warming has already affected the high northern latitudes, altering vegetation productivity, carbon sequestration, and many other ecosystem processes and services. The central-western Canadian boreal forests and aspen parkland are experiencing a decade long drought, and rainfall has been identified as a key factor controlling the location of the boundary between forest and prairie in this region. Shifting biome with related greening and browning trends are readily measureable with remote sensing, but the dynamics that create and result from them are not well understood. In this study, we use the University of Virginia Forest Model Enhanced (UVAFME), an individual-based forest model, to simulate the changes that are occurring across the southern boreal and parkland forests of west-central Canada. We present a parameterization of UVAFME for western central Canadian forests, validated with CIPHA data (Climate Change Impacts on the Productivity and Health of Aspen), and improved mortality. In order to gain a fine-scale understanding of how climate change and specifically drought will continue to affect the forests of this region, we simulated forest conditions following CMIP5 climate scenarios. UVAFME predictions were compared with statistical models and satellite observations of productivity across the landscape. Changes in forest cover, forest type, aboveground biomass, and mortality and recruitment dynamics are presented, highlighting the high vulnerability of this region to vegetation transitions associated with future droughts.

  18. Anopheline (Diptera:Culicidae) breeding in a traditional tank-based village ecosystem in north central Sri Lanka

    DEFF Research Database (Denmark)

    Amerasinghe, F P; Konradsen, F; Fonseka, K T

    1997-01-01

    A 13-mo survey of immature anopheline mosquitoes breeding in surface water habitats was done at Mahameegaswewa village within the Huruluwewa watershed in north central Sri Lanka as part of a multidisciplinary study on malaria epidemiology. The watershed is representative of the ancient small tank......-based irrigation network that still forms an important component of the rice production system in the low elevation dry zone. In total, 3,818 immatures representing 12 species were obtained from 2,940 samples taken from 5 larval habitats within the village ecosystem. Anopheles varuna Iyengar and An. culicifacies...

  19. A logic-based dynamic modeling approach to explicate the evolution of the central dogma of molecular biology.

    Science.gov (United States)

    Jafari, Mohieddin; Ansari-Pour, Naser; Azimzadeh, Sadegh; Mirzaie, Mehdi

    It is nearly half a century past the age of the introduction of the Central Dogma (CD) of molecular biology. This biological axiom has been developed and currently appears to be all the more complex. In this study, we modified CD by adding further species to the CD information flow and mathematically expressed CD within a dynamic framework by using Boolean network based on its present-day and 1965 editions. We show that the enhancement of the Dogma not only now entails a higher level of complexity, but it also shows a higher level of robustness, thus far more consistent with the nature of biological systems. Using this mathematical modeling approach, we put forward a logic-based expression of our conceptual view of molecular biology. Finally, we show that such biological concepts can be converted into dynamic mathematical models using a logic-based approach and thus may be useful as a framework for improving static conceptual models in biology.

  20. Comprehensive uranium thiophosphate chemistry: Framework compounds based on pseudotetrahedrally coordinated central metal atoms

    International Nuclear Information System (INIS)

    Neuhausen, Christine; Panthoefer, Martin; Tremel, Wolfgang; Hatscher, Stephan T.; Urland, Werner

    2013-01-01

    The new ternary compounds UP 2 S 6 , UP 2 S 7 , U(P 2 S 6 ) 2 , and U 3 (PS 4 ) 4 were prepared from uranium metal, phosphorus pentasulfide, and sulfur at 700 C. The crystal structures were determined by single-crystal X-ray diffraction methods. UP 2 S 6 (I) crystallizes in the ZrP 2 S 6 structure type [tetragonal, P4 2 /m, a = 6.8058(7) Aa, c = 9.7597(14) Aa, Z = 2], which consists of central uranium(IV) atoms coordinated by P 2 S 6 4- anions (staggered conformation). The anions are two-dimensional connectors for four uranium cations arranged in one plane. The structure of UP 2 S 7 (II) [orthorhombic, Fddd, a = 8.9966(15) Aa, b = 15.2869(2) Aa, c = 30.3195(5) Aa, Z = 16] is closely related to the monoclinic ZrP 2 S 7 structure type. It consists of U 4+ cations linked by P 2 S 7 4- ligands, the resulting 3D network contains large pores (diameter approx. 3.5 x 16.7 Aa). In the previously reported compound U(P 2 S 6 ) 2 (III) [I4 1 /a, a = 12.8776(9) Aa, c = 9.8367(10) Aa, Z = 2], the metal atoms are coordinated by four bidentate P 2 S 6 2- ligands. This arrangement can be considered as a pseudotetrahedral coordination of the uranium atoms by the linear ligands. Three of the resulting diamondoid frameworks are inseparably interwoven in order to optimize space filling. U 3 (PS 4 ) 4 (IV) [I4 1 /acd, a = 10.7440(9) Aa, c = 19.0969(2) Aa, Z = 2] crystallizes in a defect variant of the PrPS 4 structure type, with 50 % of the U2 sites statistically occupied with uranium atoms. The resulting stoichiometry is U 3 (PS 4 ) 4 with tetravalent uranium atoms. The structure of U 3 (PS 4 ) 4 consists of uranium atoms connected by PS 4 3- groups, each PS 4 group linking four central uranium atoms. Vibrational spectra, which were recorded for I-III, show good agreement between the obtained results and the expected values for the anionic units, while magnetic measurements confirm the presence of tetravalent uranium. (Copyright copyright 2013 WILEY-VCH Verlag GmbH and Co. KGa

  1. Centralized Monitoring of the Microsoft Windows-based computers of the LHC Experiment Control Systems

    International Nuclear Information System (INIS)

    Varela Rodriguez, F

    2011-01-01

    The control system of each of the four major Experiments at the CERN Large Hadron Collider (LHC) is distributed over up to 160 computers running either Linux or Microsoft Windows. A quick response to abnormal situations of the computer infrastructure is crucial to maximize the physics usage. For this reason, a tool was developed to supervise, identify errors and troubleshoot such a large system. Although the monitoring of the performance of the Linux computers and their processes was available since the first versions of the tool, it is only recently that the software package has been extended to provide similar functionality for the nodes running Microsoft Windows as this platform is the most commonly used in the LHC detector control systems. In this paper, the architecture and the functionality of the Windows Management Instrumentation (WMI) client developed to provide centralized monitoring of the nodes running different flavour of the Microsoft platform, as well as the interface to the SCADA software of the control systems are presented. The tool is currently being commissioned by the Experiments and it has already proven to be very efficient optimize the running systems and to detect misbehaving processes or nodes.

  2. Soil classification based on cone penetration test (CPT) data in Western Central Java

    Science.gov (United States)

    Apriyono, Arwan; Yanto, Santoso, Purwanto Bekti; Sumiyanto

    2018-03-01

    This study presents a modified friction ratio range for soil classification i.e. gravel, sand, silt & clay and peat, using CPT data in Western Central Java. The CPT data was obtained solely from Soil Mechanic Laboratory of Jenderal Soedirman University that covers more than 300 sites within the study area. About 197 data were produced from data filtering process. IDW method was employed to interpolated friction ratio values in a regular grid point for soil classification map generation. Soil classification map was generated and presented using QGIS software. In addition, soil classification map with respect to modified friction ratio range was validated using 10% of total measurements. The result shows that silt and clay dominate soil type in the study area, which is in agreement with two popular methods namely Begemann and Vos. However, the modified friction ratio range produces 85% similarity with laboratory measurements whereby Begemann and Vos method yields 70% similarity. In addition, modified friction ratio range can effectively distinguish fine and coarse grains, thus useful for soil classification and subsequently for landslide analysis. Therefore, modified friction ratio range proposed in this study can be used to identify soil type for mountainous tropical region.

  3. Implementation of a Real-Time Microgrid Simulation Platform Based on Centralized and Distributed Management

    Directory of Open Access Journals (Sweden)

    Omid Abrishambaf

    2017-06-01

    Full Text Available Demand response and distributed generation are key components of power systems. Several challenges are raised at both technical and business model levels for integration of those resources in smart grids and microgrids. The implementation of a distribution network as a test bed can be difficult and not cost-effective; using computational modeling is not sufficient for producing realistic results. Real-time simulation allows us to validate the business model’s impact at the technical level. This paper comprises a platform supporting the real-time simulation of a microgrid connected to a larger distribution network. The implemented platform allows us to use both centralized and distributed energy resource management. Using an optimization model for the energy resource operation, a virtual power player manages all the available resources. Then, the simulation platform allows us to technically validate the actual implementation of the requested demand reduction in the scope of demand response programs. The case study has 33 buses, 220 consumers, and 68 distributed generators. It demonstrates the impact of demand response events, also performing resource management in the presence of an energy shortage.

  4. Centralized Monitoring of the Microsoft Windows-based computers of the LHC Experiment Control Systems

    Science.gov (United States)

    Varela Rodriguez, F.

    2011-12-01

    The control system of each of the four major Experiments at the CERN Large Hadron Collider (LHC) is distributed over up to 160 computers running either Linux or Microsoft Windows. A quick response to abnormal situations of the computer infrastructure is crucial to maximize the physics usage. For this reason, a tool was developed to supervise, identify errors and troubleshoot such a large system. Although the monitoring of the performance of the Linux computers and their processes was available since the first versions of the tool, it is only recently that the software package has been extended to provide similar functionality for the nodes running Microsoft Windows as this platform is the most commonly used in the LHC detector control systems. In this paper, the architecture and the functionality of the Windows Management Instrumentation (WMI) client developed to provide centralized monitoring of the nodes running different flavour of the Microsoft platform, as well as the interface to the SCADA software of the control systems are presented. The tool is currently being commissioned by the Experiments and it has already proven to be very efficient optimize the running systems and to detect misbehaving processes or nodes.

  5. Implementation of personalized medicine in Central-Eastern Europe: pitfalls and potentials based on citizen's attitude.

    Science.gov (United States)

    Balicza, Peter; Terebessy, Andras; Grosz, Zoltan; Varga, Noemi Agnes; Gal, Aniko; Fekete, Balint Andras; Molnar, Maria Judit

    2018-03-01

    Next-generation sequencing is increasingly utilized worldwide as a research and diagnostic tool and is anticipated to be implemented into everyday clinical practice. Since Central-Eastern European attitude toward genetic testing, especially broad genetic testing, is not well known, we performed a survey on this issue among Hungarian participants. A self-administered questionnaire was distributed among patients and patient relatives at our neurogenetic outpatient clinic. Members of the general population were also recruited via public media. We used chi-square testing and binary logistic regression to examine factors influencing attitude. We identified a mixed attitude toward genetic testing. Access to physician consultation positively influenced attitude. A higher self-determined genetic familiarity score associated with higher perceived genetic influence score, which in turn associated with greater willingness to participate in genetic testing. Medical professionals constituted a skeptical group. We think that given the controversies and complexities of the next-generation sequencing field, the optimal clinical translation of NGS data should be performed in institutions which have the unique capability to provide interprofessional health education, transformative biomedical research, and crucial patient care. With optimization of the clinical translational process, improvement of genetic literacy may increase patient engagement and empowerment. The paper highlights that in countries with relatively low-genetic literacy, a special strategy is needed to enhance the implementation of personalized medicine.

  6. Nanofibrous scaffolds supporting optimal central nervous system regeneration: an evidence-based review

    Directory of Open Access Journals (Sweden)

    Kamudzandu M

    2015-12-01

    Full Text Available Munyaradzi Kamudzandu, Paul Roach, Rosemary A Fricker, Ying Yang Institute for Science and Technology in Medicine, School of Medicine, Keele University, Stoke-on-Trent, UK Abstract: Restoration of function following damage to the central nervous system (CNS is severely restricted by several factors. These include the hindrance of axonal regeneration imposed by glial scars resulting from inflammatory response to damage, and limited axonal outgrowth toward target tissue. Strategies for promoting CNS functional regeneration include the use of nanotechnology. Due to their structural similarity, synthetic nanofibers could play an important role in regeneration of CNS neural tissue toward restoration of function following injury. Two-dimensional nanofibrous scaffolds have been used to provide contact guidance for developing brain and spinal cord neurites, particularly from neurons cultured in vitro. Three-dimensional nanofibrous scaffolds have been used, both in vitro and in vivo, for creating cell adhesion permissive milieu, in addition to contact guidance or structural bridges for axons, to control reconnection in brain and spinal cord injury models. It is postulated that nanofibrous scaffolds made from biodegradable and biocompatible materials can become powerful structural bridges for both guiding the outgrowth of neurites and rebuilding glial circuitry over the “lesion gaps” resulting from injury in the CNS. Keywords: scaffold, nanofibrous scaffold, CNS, regeneration, alignment

  7. Research and application of an intelligent control system in central air-conditioning based on energy consumption simulation

    Science.gov (United States)

    Cao, Ling; Che, Wenbin

    2018-05-01

    For the central air-conditioning energy-saving, it is common practice to use a wide range of PTD controllers in engineering to optimize energy savings. However, the shortcomings of the PTD controller have also been magnified on this issue, such as: calculation accuracy is not enough, the calculation time is too long. Particle swarm optimization has the advantage of fast convergence. This paper is based on Particle Swarm Optimization apply in PTD controller tuning parameters in order to achieve the purpose of saving energy while ensuring comfort. The algorithm proposed in this paper can adjust the weight according to the change of population fitness, reduce the weights of particles with lower fitness and enhance the weights of particles with higher fitness in the population, and fully release the population vitality. The method in this paper is validated by the TRNSYS model based on the central air-conditioning system. The experimental results show that the room temperature fluctuation is small, the overshoot is small, the adjustment speed is fast, and the energy-saving fluctuates at 10%.

  8. Grey-Markov prediction model based on background value optimization and central-point triangular whitenization weight function

    Science.gov (United States)

    Ye, Jing; Dang, Yaoguo; Li, Bingjun

    2018-01-01

    Grey-Markov forecasting model is a combination of grey prediction model and Markov chain which show obvious optimization effects for data sequences with characteristics of non-stationary and volatility. However, the state division process in traditional Grey-Markov forecasting model is mostly based on subjective real numbers that immediately affects the accuracy of forecasting values. To seek the solution, this paper introduces the central-point triangular whitenization weight function in state division to calculate possibilities of research values in each state which reflect preference degrees in different states in an objective way. On the other hand, background value optimization is applied in the traditional grey model to generate better fitting data. By this means, the improved Grey-Markov forecasting model is built. Finally, taking the grain production in Henan Province as an example, it verifies this model's validity by comparing with GM(1,1) based on background value optimization and the traditional Grey-Markov forecasting model.

  9. An InSAR-based survey of volcanic deformation in the central Andes

    Science.gov (United States)

    Pritchard, M. E.; Simons, M.

    2004-02-01

    We extend an earlier interferometric synthetic aperture radar (InSAR) survey covering about 900 remote volcanos of the central Andes (14°-27°S) between the years 1992 and 2002. Our survey reveals broad (10s of km), roughly axisymmetric deformation at 4 volcanic centers: two stratovolcanoes are inflating (Uturuncu, Bolivia, and Hualca Hualca, Peru); another source of inflation on the border between Chile and Argentina is not obviously associated with a volcanic edifice (here called Lazufre); and a caldera (Cerro Blanco, also called Robledo) in northwest Argentina is subsiding. We explore the range of source depths and volumes allowed by our observations, using spherical, ellipsoidal and crack-like source geometries. We further examine the effects of local topography upon the deformation field and invert for a spherical point-source in both elastic half-space and layered-space crustal models. We use a global search algorithm, with gradient search methods used to further constrain best-fitting models. Inferred source depths are model-dependent, with differences in the assumed source geometry generating a larger range of accepted depths than variations in elastic structure. Source depths relative to sea level are: 8-18 km at Hualca Hualca; 12-25 km for Uturuncu; 5-13 km for Lazufre, and 5-10 km at Cerro Blanco. Deformation at all four volcanoes seems to be time-dependent, and only Uturuncu and Cerro Blanco were deforming during the entire time period of observation. Inflation at Hualca Hualca stopped in 1997, perhaps related to a large eruption of nearby Sabancaya volcano in May 1997, although there is no obvious relation between the rate of deformation and the eruptions of Sabancaya. We do not observe any deformation associated with eruptions of Lascar, Chile, at 16 other volcanoes that had recent small eruptions or fumarolic activity, or associated with a short-lived thermal anomaly at Chiliques volcano. We posit a hydrothermal system at Cerro Blanco to explain the

  10. Experience with a modular application system with central data base for scientific-technical calculations

    International Nuclear Information System (INIS)

    Ruehle, R.; Wohland, H.; Reyer, G.

    1976-01-01

    The basic principles of the application system RSYST are presented. This programme system is developed and used in the Institut fuer Kernenergetik (IKE). Data base, structure, and connection of data, and the application language are described. The process of problem formulation typical for RSYST is discussed. Just now the system is being extended to dialogue and remote data processing. (orig.) [de

  11. Beyond the Central Dogma: Model-Based Learning of How Genes Determine Phenotypes

    Science.gov (United States)

    Reinagel, Adam; Speth, Elena Bray

    2016-01-01

    In an introductory biology course, we implemented a learner-centered, model-based pedagogy that frequently engaged students in building conceptual models to explain how genes determine phenotypes. Model-building tasks were incorporated within case studies and aimed at eliciting students' understanding of 1) the origin of variation in a population…

  12. Stem and Progenitor Cell-Based Therapy of the Central Nervous System

    DEFF Research Database (Denmark)

    Goldman, Steven A.

    2016-01-01

    A variety of neurological disorders are attractive targets for stem and progenitor cell-based therapy. Yet many conditions are not, whether by virtue of an inhospitable disease environment, poorly understood pathophysiology, or poor alignment of donor cell capabilities with patient needs. Moreove...

  13. Movimientos de base indígena y fase pre-constituyente de Bolivia (Tema Central)

    OpenAIRE

    Sandoval, Carla

    2007-01-01

    El presente artículo ofrece un panorama de la conformación de espacios de reflexión y diálogo abiertos por las organizaciones de base indígenas de los movimientos sociales de Bolivia durante el periodo Pre-constituyente.

  14. An EEG-Based Biometric System Using Eigenvector Centrality in Resting State Brain Networks

    NARCIS (Netherlands)

    Fraschini, M.; Hillebrand, A.; Demuru, M.; Didaci, L.; Marcialis, G.L.

    2015-01-01

    Recently, there has been a growing interest in the use of brain activity for biometric systems. However, so far these studies have focused mainly on basic features of the Electroencephalography. In this study we propose an approach based on phase synchronization, to investigate personal distinctive

  15. Performance enhancement of photovoltaic array through string and central based MPPT system under non-uniform irradiance conditions

    International Nuclear Information System (INIS)

    Syafaruddin; Karatepe, Engin; Hiyama, Takashi

    2012-01-01

    Highlights: ► We propose MPPT method for tracking global MPP of PV arrays under non-uniform irradiance conditions. ► We compare the performance of string and central based MPPT. ► Intelligent control method is utilized to identify the global operating voltage in string and central based MPPT system. ► The performance of proposed method is tested on different size of PV. - Abstract: Mismatching losses reduction of photovoltaic (PV) array has been intensively discussed through the increasing penetration of residential and commercial PV systems. Many causes of mismatching losses have been identified and plenty of proposed methods to solve this problem have been recently proposed. This paper deals with reducing method of mismatching losses due to the non-uniform irradiance conditions. It is well-known that a certain number of multiple peaks occur on the power–voltage curve as the number of PV modules in one-string increases under non-uniform operating conditions. Since the conventional control method only drives the operating points of PV system to the local maxima close to open circuit voltage, only small portion of power can be extracted from the PV system. In this study, a radial basis function neural network (RBF-ANN) based intelligent control method is utilized to map the global operating voltage and non-irradiance operating condition in string and central based MPPT systems. The proposed method has been tested on 10 × 3 (2.2 kW), 15 × 3 (2.5 kW) and 20 × 3 (3.3 kW) of series–parallel PV array configuration under random-shaded and continuous-shaded patterns. The proposed method is compared with the ideal case and conventional method through a simple power–voltage curve of PV arrays. The simulation results show that there are significant increases of about 30–60% of the extracted power in one operating condition when the proposed method is able to shift the operating voltage of modules to their optimum voltages.

  16. Management and hazardous waste characterization in Central for Isotop and Radiation Application based on potential dangers

    International Nuclear Information System (INIS)

    Niken Hayudanti Anggarini; Megi Stefanus; Prihatiningsih

    2014-01-01

    Separating and storing hazardous waste have been done based on the physical, chemical, and based on potential dangers due to safety hazardous waste temporary storage warehouse. From the results of data collection in 2014 found that the most dominant hazardous waste is organic liquid waste which reaches 61 %, followed by inorganic liquid waste 33 % while organic solid waste and inorganic solid waste has a small portion. When viewed from potential danger, flammable liquid waste has the greatest volume percentage it is 47 % and is followed by a corrosive liquid waste 26 %, while the liquid waste that has not been identified is quite large, which is 9 %. From the highest hazard potential data, hazardous waste storage warehouse is required to have good air circulation and waste storage shelf protected from direct solar heat. Cooperation of lab workers and researchers are also indispensable in providing identification of each waste generated to facilitate the subsequent waste management. (author)

  17. Comparative Analysis of Reward and Employee Performance Based on Gender at Central Bank of Bank Sulut

    OpenAIRE

    Pandowo, Merinda; Lapian, S.L.H.V Joyce; Oroh, Ryan Vitaly

    2014-01-01

    Employee are the big asset of organization. Employee Performance are have big effect of organization performance. The best way to attract employee performance is rewarding employee. Reward can be tangible such money, bonuses or called extrinsic reward and intangible reward such promotion, holiday or called intrinsic reward. The purpose of this research are to analyzed significant differences in employee performance based on reward between male and female. To achieve the objectives researcher ...

  18. Osteomyelite atypique ou centrale de la base du crane d'origine ...

    African Journals Online (AJOL)

    Introduction : L'ostéomyélitede la base du crâne esttypiquement secondaire à une otite externe nécrosante chez des patients âgés, diabétiques. Elle atteint l'os temporal et est habituellement due au pseudomonasaeruginosa. Dans sa forme atypique, l'ostéomyélite atteint les os sphénoïdal ou occipital sans otite externe ...

  19. GIS-based seismic shaking slope vulnerability map of Sicily (Central Mediterranean)

    Science.gov (United States)

    Nigro, Fabrizio; Arisco, Giuseppe; Perricone, Marcella; Renda, Pietro; Favara, Rocco

    2010-05-01

    permanent displacement potentially induced by an seismic scenario. Such methodologies found on the consideration that the conditions of seismic stability and the post-seismic functionality of engineering structures are tightly related to the entity of the permanent deformations that an earthquake can induce. Regarding the existing simplified procedures among slope stability models, Newmark's model is often used to derive indications about slope instabilities due to earthquakes. In this way, we have evaluated the seismically-induced landslides hazard in Sicily (Central Mediterranean) using the Newmark-like model. In order to determine the map distribution of the seismic ground-acceleration from an earthquake scenario, the attenuation-law of Sabetta & Pugliese has been used, analyzing some seismic recordings occurred in Italy. Also, by evaluating permanent displacements, the correlation of Ambraseys & Menu has been assumed. The seismic shaking slope vulnerability map of Sicily has been carried out using GIS application, also considering max seismic ground-acceleration peak distribution (in terms of exceedance probability for fixed time), slope acclivity, cohesion/angle of internal friction of outcropping rocks, allowing the zoning of the unstable slopes under seismic forces.

  20. Age assessment based on third molar mineralisation : An epidemiological-radiological study on a Central-European population.

    Science.gov (United States)

    Hofmann, Elisabeth; Robold, Matthias; Proff, Peter; Kirschneck, Christian

    2017-03-01

    The method published in 1973 by Demirjian et al. to assess age based on the mineralisation stage of permanent teeth is standard practice in forensic and orthodontic diagnostics. From age 14 onwards, however, this method is only applicable to third molars. No current epidemiological data on third molar mineralisation are available for Caucasian Central-Europeans. Thus, a method for assessing age in this population based on third molar mineralisation is presented, taking into account possible topographic and gender-specific differences. The study included 486 Caucasian Central-European orthodontic patients (9-24 years) with unaffected dental development. In an anonymized, randomized, and blinded manner, one orthopantomogram of each patient at either start, mid or end of treatment was visually analysed regarding the mineralisation stage of the third molars according to the method by Demirjian et al. Corresponding topographic and gender-specific point scores were determined and added to form a dental maturity score. Prediction equations for age assessment were derived by linear regression analysis with chronological age and checked for reliability within the study population. Mineralisation of the lower third molars was slower than mineralisation of the upper third molars, whereas no jaw-side-specific differences were detected. Gender-specific differences were relatively small, but girls reached mineralisation stage C earlier than boys, whereas boys showed an accelerated mineralisation between the ages of 15 and 16. The global equation generated by regression analysis (age = -1.103 + 0.268 × dental maturity score 18 + 28 + 38 + 48) is sufficiently accurate and reliable for clinical use. Age assessment only based on either maxilla or mandible also shows good prognostic reliability.

  1. Configuring calendar variation based on time series regression method for forecasting of monthly currency inflow and outflow in Central Java

    Science.gov (United States)

    Setiawan, Suhartono, Ahmad, Imam Safawi; Rahmawati, Noorgam Ika

    2015-12-01

    Bank Indonesia (BI) as the central bank of Republic Indonesiahas a single overarching objective to establish and maintain rupiah stability. This objective could be achieved by monitoring traffic of inflow and outflow money currency. Inflow and outflow are related to stock and distribution of money currency around Indonesia territory. It will effect of economic activities. Economic activities of Indonesia,as one of Moslem country, absolutely related to Islamic Calendar (lunar calendar), that different with Gregorian calendar. This research aims to forecast the inflow and outflow money currency of Representative Office (RO) of BI Semarang Central Java region. The results of the analysis shows that the characteristics of inflow and outflow money currency influenced by the effects of the calendar variations, that is the day of Eid al-Fitr (moslem holyday) as well as seasonal patterns. In addition, the period of a certain week during Eid al-Fitr also affect the increase of inflow and outflow money currency. The best model based on the value of the smallestRoot Mean Square Error (RMSE) for inflow data is ARIMA model. While the best model for predicting the outflow data in RO of BI Semarang is ARIMAX model or Time Series Regression, because both of them have the same model. The results forecast in a period of 2015 shows an increase of inflow money currency happened in August, while the increase in outflow money currency happened in July.

  2. Hydro, wind and solar power as a base for a 100% renewable energy supply for South and Central America.

    Directory of Open Access Journals (Sweden)

    Larissa de Souza Noel Simas Barbosa

    Full Text Available Power systems for South and Central America based on 100% renewable energy (RE in the year 2030 were calculated for the first time using an hourly resolved energy model. The region was subdivided into 15 sub-regions. Four different scenarios were considered: three according to different high voltage direct current (HVDC transmission grid development levels (region, country, area-wide and one integrated scenario that considers water desalination and industrial gas demand supplied by synthetic natural gas via power-to-gas (PtG. RE is not only able to cover 1813 TWh of estimated electricity demand of the area in 2030 but also able to generate the electricity needed to fulfil 3.9 billion m3 of water desalination and 640 TWhLHV of synthetic natural gas demand. Existing hydro dams can be used as virtual batteries for solar and wind electricity storage, diminishing the role of storage technologies. The results for total levelized cost of electricity (LCOE are decreased from 62 €/MWh for a highly decentralized to 56 €/MWh for a highly centralized grid scenario (currency value of the year 2015. For the integrated scenario, the levelized cost of gas (LCOG and the levelized cost of water (LCOW are 95 €/MWhLHV and 0.91 €/m3, respectively. A reduction of 8% in total cost and 5% in electricity generation was achieved when integrating desalination and power-to-gas into the system.

  3. Hydro, wind and solar power as a base for a 100% renewable energy supply for South and Central America.

    Science.gov (United States)

    Barbosa, Larissa de Souza Noel Simas; Bogdanov, Dmitrii; Vainikka, Pasi; Breyer, Christian

    2017-01-01

    Power systems for South and Central America based on 100% renewable energy (RE) in the year 2030 were calculated for the first time using an hourly resolved energy model. The region was subdivided into 15 sub-regions. Four different scenarios were considered: three according to different high voltage direct current (HVDC) transmission grid development levels (region, country, area-wide) and one integrated scenario that considers water desalination and industrial gas demand supplied by synthetic natural gas via power-to-gas (PtG). RE is not only able to cover 1813 TWh of estimated electricity demand of the area in 2030 but also able to generate the electricity needed to fulfil 3.9 billion m3 of water desalination and 640 TWhLHV of synthetic natural gas demand. Existing hydro dams can be used as virtual batteries for solar and wind electricity storage, diminishing the role of storage technologies. The results for total levelized cost of electricity (LCOE) are decreased from 62 €/MWh for a highly decentralized to 56 €/MWh for a highly centralized grid scenario (currency value of the year 2015). For the integrated scenario, the levelized cost of gas (LCOG) and the levelized cost of water (LCOW) are 95 €/MWhLHV and 0.91 €/m3, respectively. A reduction of 8% in total cost and 5% in electricity generation was achieved when integrating desalination and power-to-gas into the system.

  4. Aetiologies of central nervous system infection in Viet Nam: a prospective provincial hospital-based descriptive surveillance study.

    Directory of Open Access Journals (Sweden)

    Nghia Ho Dang Trung

    Full Text Available Infectious diseases of the central nervous system (CNS remain common and life-threatening, especially in developing countries. Knowledge of the aetiological agents responsible for these infections is essential to guide empiric therapy and develop a rational public health policy. To date most data has come from patients admitted to tertiary referral hospitals in Asia and there is limited aetiological data at the provincial hospital level where most patients are seen.We conducted a prospective Provincial Hospital-based descriptive surveillance study in adults and children at thirteen hospitals in central and southern Viet Nam between August 2007-April 2010. The pathogens of CNS infection were confirmed in CSF and blood samples by using classical microbiology, molecular diagnostics and serology.We recruited 1241 patients with clinically suspected infection of the CNS. An aetiological agent was identified in 640/1241 (52% of the patients. The most common pathogens were Streptococcus suis serotype 2 in patients older than 14 years of age (147/617, 24% and Japanese encephalitis virus in patients less than 14 years old (142/624, 23%. Mycobacterium tuberculosis was confirmed in 34/617 (6% adult patients and 11/624 (2% paediatric patients. The acute case fatality rate (CFR during hospital admission was 73/617 (12% in adults and to 42/624 (7% in children.Zoonotic bacterial and viral pathogens are the most common causes of CNS infection in adults and children in Viet Nam.

  5. Electronic medical record in central polyclinic of isfahan oil industry: a case study based on technology acceptance model.

    Science.gov (United States)

    Tavakoli, Nahid; Jahanbakhsh, Maryam; Shahin, Arash; Mokhtari, Habibollah; Rafiei, Maryam

    2013-03-01

    Today, health information technologies are base of health services and Electronic Medical Record is one of them. The purpose of this paper is to investigate the Technology Acceptance Model (TAM) on EMR at Central Polyclinic Oil Industry that is a pioneer in implementation of EMR in Isfahan. This study was an applied and analytical survey that it was done at the Central Polyclinic Oil Industry. Because statistical population were limited, sampling bas been done by conducting the census and the sample was according to the population. The data was collected by a researcher-made questionnaire that it was validated by experts and its reliability was confirmed by test retest. The questionnaire was developed in 5 scopes including external factors (data quality and user interface), perceived usefulness, perceived ease of usefulness, attitude toward using, and behavioral intention to use. The Results analyzed by SPSS. There was a significant relationship between data quality with PU(r=/295, p/005). The survey of the scopes in the polyclinic showed that there is relationship among user interface, perceived usefulness, perceived ease of usefulness, attitude toward using, and behavioral intention to use, but data quality has no relationship with attitude. It seems the system designers didn't consider to data quality characteristics. It is proposed that they consult with health information management professionals for improvement the existing system.

  6. Post-early Messinian counterclockwise rotations on Crete: implications for Late Miocene to Recent kinematics of the southern Hellenic arc

    NARCIS (Netherlands)

    Duermeijer, C.E.; Krijgsman, W.; Langereis, C.G.; Veen, J.H. ten

    1998-01-01

    Most geodynamical models for the kinematics of the central Mediterranean recognise that major tectonic rotations must have played an important role during the Neogene. The Hellenic arc is believed to have been subjected to clockwise rotations in the west and counterclockwise rotations in the east,

  7. Transportation Network Role for Central Italy Macroregion Development in a Territorial Frames Model Based

    Science.gov (United States)

    Di Ludovico, Donato; D'Ovidio, Gino

    2017-10-01

    This paper refers to an interdisciplinary planning research approach that aims to combine urban aspects related to a territorial spatial development with transport requirements connected to an efficiency and sustainable mobility. The proposed research method is based on “Territorial Frames” (TFs) model that derived from an original interpretation of the local context divided into a summation of territorial settlement fabrics characterized in terms of spatial tile, morphology and mobility axes. The TFs, with their own autonomous, different size and structure, are used as the main plot, able to assemble the settlement systems and their posturbane forms. With a view to polycentric and spatial development, the research method allows us to analyse the completeness of the TFs and their connective potential, in order to locate the missing/inefficient elements of the transportation network and planning other TFs essential to support economic and social development processes of the most isolated and disadvantaged inland areas. Finally, a case study of the Italian Median Macroregion configuration based on TFs model approach is proposed, analysed and discussed.

  8. Prevalence of tics in schoolchildren in central Spain: a population-based study.

    Science.gov (United States)

    Cubo, Esther; Gabriel y Galán, José María Trejo; Villaverde, Vanesa Ausín; Velasco, Sara Sáez; Benito, Vanesa Delgado; Macarrón, Jesús Vicente; Guevara, José Cordero; Louis, Elan D; Benito-León, Julián

    2011-08-01

    Tic disorders constitute a neurodevelopmental disorder of childhood. This study sought to determine the prevalence of tic disorders in a school-based sample. A randomized sample of 1158 schoolchildren, based on clusters (classrooms) in the province of Burgos (Spain), was identified on a stratified sampling frame combining types of educational center and setting (mainstream schools and special education), using a two-phase approach (screening and diagnosis ascertainment by a neurologist). Tics with/without impairment criterion were diagnosed according to Diagnostic and Statistical Manual of Mental Disorders criteria. In mainstream schools, tics were observed in 125/741 students (16.86%; 95% confidence interval, 14.10-19.63), and were more frequent in boys (87/448, 19.42%; 95% confidence interval, 15.64-23.19) compared with girls (38/293, 12.96%; 95% confidence interval, 8.95-16.98; P = 0.03). In special education centers, tics disorders were observed in 11/54 of children (20.37%; 95% confidence interval, 8.70-32.03). Overall, tics with impairment criteria were less frequent than tics without impairment criteria (4.65% vs 11.85%, P tics (6.07%) and Tourette syndrome (5.26%). Tic disorders are common in childhood, and the use or nonuse of impairment criteria exerts a significant impact on tic prevalence estimates. Copyright © 2011 Elsevier Inc. All rights reserved.

  9. A simple fish-based approach to assess the ecological quality of freshwater reservoirs in Central Europe

    Directory of Open Access Journals (Sweden)

    Blabolil Petr

    2017-01-01

    Full Text Available The assessment of ecological quality in freshwater ecosystems is a key issue in many countries, but conditions for the development of assessment methodologies are often country-specific. This study proposes a simple methodology for the assessment of the ecological potential of reservoirs based on fish communities using a dataset covering major environmental and pressure gradients in reservoirs in the Czech Republic. Fish data obtained by gillnet sampling were correlated with a proxy of eutrophication as a key indicator of anthropogenic pressure for selecting appropriate fish-based indicators, establishing scoring criteria and developing the index of ecological quality. Expert judgement was also used to select potential fish indicators. Nine indicators were selected for the final fish-based index, fulfilling the criteria required by the Water Framework Directive. Two steps were used to validate the fish-based index quantification of its inter annual stability and sensitivity analysis of individual indicators. Finally, the index was compared to a previously developed general index for Central and Western Europe. Our study demonstrates that a combination of expert judgement and strict validation methods can result in an informative assessment of the ecological conditions, which can help identify conservation and restoration priorities.

  10. A role for fragment-based drug design in developing novel lead compounds for central nervous system targets

    Directory of Open Access Journals (Sweden)

    Michael J. Wasko

    2015-09-01

    Full Text Available Hundreds of millions of U.S. dollars are invested in the research and development of a single drug. Lead compound development is an area ripe for new design strategies. Therapeutic lead candidates have been traditionally found using high-throughput in vitro pharmacologic screening, a costly method for assaying thousands of compounds. This approach has recently been augmented by virtual screening, which employs computer models of the target protein to narrow the search for possible leads. A variant of virtual screening is fragment-based drug design, an emerging in silico lead discovery method that introduces low molecular weight fragments, rather than intact compounds, into the binding pocket of the receptor model. These fragments serve as starting points for growing the lead candidate. Current efforts in virtual fragment-based drug design within central nervous system (CNS targets are reviewed, as is a recent rule-based optimization strategy in which new molecules are generated within a 3D receptor binding pocket using the fragment as a scaffold. This process places special emphasis on creating synthesizable molecules but also exposes computational questions worth addressing. Fragment-based methods provide a viable, relatively low-cost alternative for therapeutic lead discovery and optimization that can be applied to CNS targets to augment current design strategies.

  11. The application of fuzzy-based methods to central nerve fiber imaging

    DEFF Research Database (Denmark)

    Axer, Hubertus; Jantzen, Jan; Keyserlingk, Diedrich Graf v.

    2003-01-01

    This paper discusses the potential of fuzzy logic methods within medical imaging. Technical advances have produced imaging techniques that can visualize structures and their functions in the living human body. The interpretation of these images plays a prominent role in diagnostic and therapeutic...... decisions, so physicians must deal with a variety of image processing methods and their applications.This paper describes three different sources of medical imagery that allow the visualization of nerve fibers in the human brain: (1) an algorithm for automatic segmentation of some parts of the thalamus....... Fuzzy logic methods were applied to analyze these pictures from low- to high-level image processing. The solutions presented here are motivated by problems of routine neuroanatomic research demonstrating fuzzy-based methods to be valuable tools in medical image processing....

  12. Network centrality based team formation: A case study on T-20 cricket

    Directory of Open Access Journals (Sweden)

    Paramita Dey

    2017-07-01

    Full Text Available This paper proposes and evaluates the novel utilization of small world network properties for the formation of team of players with both best performances and best belongingness within the team network. To verify this concept, this methodology is applied to T-20 cricket teams. The players are treated as nodes of the network, whereas the number of interactions between team members is denoted as the edges between those nodes. All intra country networks form the cricket network for this case study. Analysis of the networks depicts that T-20 cricket network inherits all characteristics of small world network. Making a quantitative measure for an individual performance in the team sports is important with respect to the fact that for team selection of an International match, from pool of best players, only eleven players can be selected for the team. The statistical record of each player considered as a traditional way of quantifying the performance of a player. But the other criteria such as performing against a strong opponent or performance as an effective team member such as fielding, running between the wickets, good partnership deserves more credential. In this paper a revised method based on social networking is presented to quantify the quality of team belongingness and efficiency of each player. The application of Social Network Analysis (SNA is explored to measure performances and the rank of the players. A bidirectional weighted network of players is generated using the information collected from T-20 cricket (2014–2016 and used for network analysis. Thus team was formed based on that ranking and compared with their IPL (Indian Premier League performances of 2016.

  13. Short time scale laws in self-potentialsignals from two different seismically active Mediterranean areas(the Southern Apennine chainand Crete Island

    Directory of Open Access Journals (Sweden)

    M. Macchiato

    2001-06-01

    Full Text Available Self-potential time series are investigated to characterise self-potential time scales. The data analysed were recorded in stations located in two active seismic areas of the Mediterranean region, the Southern Apennine chain (Giuliano and Crete Island (Heraklion, where in past and recent years many destructive seismic events have taken place. The seismological and geological settings, combined with a low level of cultural noise, allow us to consider these areas ideal outdoor laboratories to study the time dynamics of geophysical parameters of electrical nature. At the same time, the different seismological features of such areas make an inter-comparison between the geoelectrical variability observed at the two sites interesting. Fractal analysis tools, able to detect scale laws and quantify persistence features, are used to better understand the background variability properties of the self-potential signals. As results from our analysis, antipersistence seems to be a ubiquitous feature on short time scales (minutes regardless of environmental conditions. On such scales, the accumulation of random fluctuations is not particularly efficient and significant variations mostly occur as sudden jumps.

  14. Studying the association between musculoskeletal disorders, quality of life and mental health. A primary care pilot study in rural Crete, Greece

    Directory of Open Access Journals (Sweden)

    Hadjipavlou Alexander G

    2009-11-01

    Full Text Available Abstract Background The burden of musculoskeletal disorders (MSD on the general health and well-being of the population has been documented in various studies. The objective of this study was to explore the association between MSD and the quality of life and mental health of patients and to discuss issues concerning care seeking patterns in rural Greece. Methods Patients registered at one rural Primary Care Centre (PCC in Crete were invited to complete the Nordic Musculoskeletal Questionnaire (NMQ for the analysis of musculoskeletal symptoms, together with validated instruments for measuring health related quality of life (SF-36 and mental distress (GHQ-28. Results The prevalence rate of MSD was found to be 71.2%, with low back and knee pain being the most common symptoms. Most conditions significantly impaired the quality of life, especially the physical dimensions of SF-36. Depression was strongly correlated to most MSD (p Conclusion Musculoskeletal disorders were common in patients attending the rural PCC of this study and were associated with a poor quality of life and mental distress that affected their consultation behaviour.

  15. Groundwater footprint methodology as policy tool for balancing water needs (agriculture & tourism) in water scarce islands - The case of Crete, Greece.

    Science.gov (United States)

    Kourgialas, Nektarios N; Karatzas, George P; Dokou, Zoi; Kokorogiannis, Andreas

    2018-02-15

    In many Mediterranean islands with limited surface water resources, the growth of agricultural and touristic sectors, which are the main water consumers, highly depends on the sustainable water resources management. This work highlights the crucial role of groundwater footprint (GF) as a tool for the sustainable management of water resources, especially in water scarce islands. The groundwater footprint represents the water budget between inflows and outflows in an aquifer system and is used as an index of the effect of groundwater use in natural resources and environmental flows. The case study presented in this paper is the island of Crete, which consists of 11 main aquifer systems. The data used for estimating the groundwater footprint in each system were groundwater recharges, abstractions through 412 wells, environmental flows (discharges) from 76 springs and 19 streams present in the area of study. The proposed methodology takes into consideration not only the water quantity but also the water quality of the aquifer systems and can be used as an integrated decision making tool for the sustainable management of groundwater resources. This methodology can be applied in any groundwater system. The results serve as a tool for assessing the potential of sustainable use and the optimal distribution of water needs under the current and future climatic conditions, considering both quantitative and qualitative factors. Adaptation measures and water policies that will effectively promote sustainable development are also proposed for the management of the aquifer systems that exhibit a large groundwater footprint. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Theseus is shaping up. 50 MW solar thermal power plant projected on Crete; Projekt Theseus nimmt Gestalt an. Solarthermisches 50-MW-Kraftwerk auf Kreta in Planung

    Energy Technology Data Exchange (ETDEWEB)

    Bachmann, O.; Brakmann, G. [Fichtner GmbH und Co. KG, Stuttgart (Germany)

    1998-10-01

    On the Greek island of Crete, with 8331 km{sup 2}, electric power is mainly generated by combustion of oil. This will change with Theseus (Thermal Solar European Power Station). Theseus is projected on a site with 2,200 sunshine hours per annum. The power station will cost around 125 Mio. ECU. It will have a capacity of 50 MWe. An auxiliary fossil-fuel boiler will provide steam for the turbines in the evening hours and in times of low insolation. Theseus is being constructed by a consortium under German leadership (orig.) [Deutsch] Auf der 8331 km{sup 2} grossen Insel Kreta wird die elektrische Energie bisher zum ueberwiegenden Teil durch Verbrennen von Oel erzeugt. Dies soll sich mit Theseus (Thermal Solar European Power Station) aendern. Theseus wird an einem Ort, der 2.200 Stunden pro Jahr Solarbetrieb gewaehrleistet, errichtet. Das rund 135 Mio. ECU teure Kraftwerk soll 50 MWe leisten und mit einem zusaetzlichen konventionellen, fossil gefeuerten Kessel ausgeruestet werden, der in den Abendstunden und bei geringer Sonnenstrahlung Dampf fuer die Turbinen erzeugt. Fuer die Realisierung von Theseus hat sich ein unter deutscher Leitung stehendes Konsortium gebildet. (orig./AKF)

  17. Diogene: A 4π detector, based on a time projection chamber, for studying central collisions of relativistic heavy ions

    International Nuclear Information System (INIS)

    Gosset, J.

    1981-01-01

    'Diogene' is the name we have chosen for a 4π solid angle detector, based on a Time Projection Chamber, designed to perform exclusive measurements of charged particles emitted in central collisions or relativistic heavy ions. This detector is being developed by a collaboration between physicists from Saclay, Strasbourg and Clermont Ferrand, to be installed at the Saturne Synchrotron in Saclay. I first give the motivations for our choice of a TPC rather than any other kind of detector, then I recall the principle of such a detector, before describing it with more detail and describing its present status and forsean capabilities, including some discussion about the possible extension of such a detector towards higher energies and/or heavier beams. (orig.)

  18. Diogene: a 4π detector, based on a time projection chamber, for studying central collisions of relativistic heavy ions

    International Nuclear Information System (INIS)

    Gosset, J.

    1980-10-01

    'Diogene' is the name we have chosen for a 4π solid angle detector, based on a Time Projection Chamber (TPC), designed to perform exclusive measurements of charged particles emitted in central collisions or relativistic heavy ions This detector is being developed by a collaboration between physicists from Saclay, Strasbourg and Clermont-Ferrand, to be installed at the Saturne Synchrotron in Saclay. I shall first give the motivations for our choice of a TPC rather than any other kind of detector, than recall the principle of such a detector, before describing it with more detail and describing its present status and forsean capabilities, including some discussion about the possible extension of such a detector towards higher energies and/or heavier beams

  19. Tensor algebra-based geometric methodology to codify central chirality on organic molecules.

    Science.gov (United States)

    García-Jacas, C R; Marrero-Ponce, Y; Hernández-Ortega, T; Martinez-Mayorga, K; Cabrera-Leyva, L; Ledesma-Romero, J C; Aguilera-Fernández, I; Rodríguez-León, A R

    2017-06-01

    A novel mathematical procedure to codify chiral features of organic molecules in the QuBiLS-MIDAS framework is introduced. This procedure constitutes a generalization to that commonly used to date, where the values 1 and -1 (correction factor) are employed to weight the molecular vectors when each atom is labelled as R (rectus) or S (sinister) according to the Cahn-Ingold-Prelog rules. Therefore, values in the range [Formula: see text] with steps equal to 0.25 may be accounted for. The atoms labelled R or S can have negative and positive values assigned (e.g. -3 for an R atom and 1 for an S atom, or vice versa), opposed values (e.g. -3 for an R atom and 3 for an S atom, or vice versa), positive values (e.g. 3 for an R atom and 1 for an S atom) or negative values (e.g. -3 for an R atom and -1 for an S atom). These proposed Chiral QuBiLS-MIDAS 3D-MDs are real numbers, non-symmetric and reduced to 'classical' (non-chiral) QuBiLS-MIDAS 3D-MDs when symmetry is not codified (correction factor equal to zero). In this report, only the factors with opposed values were considered with the purpose of demonstrating the feasibility of this proposal. From QSAR modelling carried out on four chemical datasets (Cramer's steroids, fenoterol stereoisomer derivatives, N-alkylated 3-(3-hydroxyphenyl)-piperidines, and perindoprilat stereoisomers), it was demonstrated that the use of several correction factors contributes to the building of models with greater robustness and predictive ability than those reported in the literature, as well as with respect to the models exclusively developed with QuBiLS-MIDAS 3D-MDs based on the factor 1 | -1. In conclusion, it can be stated that this novel strategy constitutes a suitable alternative to computed chirality-based descriptors, contributing to the development of good models to predict properties depending on symmetry.

  20. Chordoma versus chondrosarcoma of the central skull base: MR and CT findings

    International Nuclear Information System (INIS)

    Choi, Guk Myeong; Han, Moon Hee; Chang, Kee Hyun; Kim, Hong Dae; Yeon, Kyung Mo; Kim, Sam Soo

    1998-01-01

    It is known that due to both their imaging and pathologic features, the accurate differentiation of chondrosarcoma from chordoma is difficult. Through an analysis of MR and CT finding, this study aims to determine the differential points between these two tumors. In 21 patients, CT and MR imaging studies of chordoma (n=12) and chondrosarcoma (n=9) at the base of the skull were retrospectively reviewed. Diagnosis had been established by histologic examination of surgically removed specimens. Eleven of the chordomas were subclassified as conventional and one as chondroid ; eight chondrosarcoma were conventional and one was myxoid. Four chordoma patients underwent CT and MR ; in six, only MR was in one, only CT was performed. All scans were retrospectively evaluated for the location (midline/off-midline), direction of extension, margin and shape, bony destruction and calcification, MR signal intensity and enhancement patterns of the tumors. Degree of calcification was graded from I to II. Although MR and CT findings were similar in both types of tumor, location and degree of calcification may be features which usefully distinguish chordoma from chondrosarcoma. (author). 17 refs., 2 tabs., 5 figs

  1. Association of tic disorders with poor academic performance in central Spain: a population-based study.

    Science.gov (United States)

    Cubo, Esther; Trejo, José; Ausín, Vanesa; Sáez, Sara; Delgado, Vanesa; Macarrón, Jesus; Cordero, José; Louis, Elan D; Kompoliti, Katie; Benito-León, Julián

    2013-07-01

    To analyze the association between tic disorders and poor academic performance in school-aged children. This was a cross-sectional, observational study conducted in a randomly selected sample of mainstream school-aged children (aged 6-16 years). The sampling frame included different types of schools and educational levels. Children with poor academic performance (eg, repeating a grade, special needs), and tic disorders (defined based on Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision criteria) were identified. Children with and without tics and children with and without poor academic performance were compared in terms of clinical features (ie, medical history and neurologic and psychiatric comorbidities), school, and environmental characteristics. Logistic regression analyses were performed using school performance (dependent variable) and tic disorders (independent variable), after adjusting for confounding variables. The study cohort comprised 1867 children (mean age, 10.9 + 2.9 years; 1007 males [53.9%]). Tics were present in 162 children (8.6%), and poor academic performance was noted in 223 (11.9%). Overall poor academic performance was associated with age (OR, 1.71; P family history of school dysfunction (OR, 2.43; P = .02) and was negatively associated with higher IQ score (OR, 0.90; P academic performance in our cohort. Early academic support and modification of environmental characteristics are needed for children at higher risk for school dysfunction, to enhance academic performance. Copyright © 2013 Mosby, Inc. All rights reserved.

  2. Climate Based Façade Design for Business Buildings with Examples from Central London

    Directory of Open Access Journals (Sweden)

    John Napier

    2015-01-01

    Full Text Available There is a disconnection between commercial architecture and environmental thinking, where green features can be included as part of a strategy for gaining approvals and marketing projects, but those features are not reviewed after completion and occupation of the building and knowledge is not shared. High levels of air conditioning are still considered unavoidable. Elaborate double skin façades and complex motorized shading systems are adopted; often masking an underlying lack of basic environmental thinking. This article returns (in principle to the physics of comfort in buildings and the passive strategies which can help achieve this with a low energy and carbon footprint. Passive and active façade design strategies are outlined as the basis of a critical tool and a design methodology for new projects. A new architectural sensibility can arise based on modeling the inputs of sunlight, daylight and air temperature in time and space at the early stages of design. Early but sound strategies can be tested and refined using advanced environmental modeling techniques. Architecture and environmental thinking can proceed hand in hand through the design process.

  3. Ranking candidate disease genes from gene expression and protein interaction: a Katz-centrality based approach.

    Directory of Open Access Journals (Sweden)

    Jing Zhao

    Full Text Available Many diseases have complex genetic causes, where a set of alleles can affect the propensity of getting the disease. The identification of such disease genes is important to understand the mechanistic and evolutionary aspects of pathogenesis, improve diagnosis and treatment of the disease, and aid in drug discovery. Current genetic studies typically identify chromosomal regions associated specific diseases. But picking out an unknown disease gene from hundreds of candidates located on the same genomic interval is still challenging. In this study, we propose an approach to prioritize candidate genes by integrating data of gene expression level, protein-protein interaction strength and known disease genes. Our method is based only on two, simple, biologically motivated assumptions--that a gene is a good disease-gene candidate if it is differentially expressed in cases and controls, or that it is close to other disease-gene candidates in its protein interaction network. We tested our method on 40 diseases in 58 gene expression datasets of the NCBI Gene Expression Omnibus database. On these datasets our method is able to predict unknown disease genes as well as identifying pleiotropic genes involved in the physiological cellular processes of many diseases. Our study not only provides an effective algorithm for prioritizing candidate disease genes but is also a way to discover phenotypic interdependency, cooccurrence and shared pathophysiology between different disorders.

  4. The Central Role of Physician Leadership for Driving Change in Value-Based Care Environments.

    Science.gov (United States)

    Lustig, Adam; Ogden, Michael; Brenner, Robert W; Penso, Jerry; Westrich, Kimberly D; Dubois, Robert W

    2016-10-01

    has achieved 72% hypertension control for at-risk patients and continues work towards the 80% campaign goal. The implementation of the Measure Up/Pressure Down campaign by CHC and SMG provides some valuable lessons. To further explore important aspects of successfully implementing the Measure Up/Pressure Down campaign in real-world settings, 6 key themes were identified that drove quality improvement and may be helpful to other organizations that implement similar quality improvement initiatives: (1) transitioning to value-based payments, (2) creating an environment for success, (3) leveraging program champions, (4) sharing quality data, (5) promoting care team collaboration, and (6) leveraging health information technology. The strategies employed by SMG and CHC, such as leveraging data analysis to identify at-risk patients and comparing physician performance, as well as identifying leaders to institute change, can be replicated by an ACO or a managed care organization (MCO). An MCO can provide data analysis services, sparing the provider groups the analytic burden and helping the MCO build a more meaningful relationship with their providers. No outside funding supported this project. The authors declare no conflicts of interest. The authors are members of the Working Group on Optimizing Medication Therapy in Value-Based Healthcare. Odgen is employed by Cornerstone Health Care; Brenner is employed by Summit Medical Group; and Penso is employed by American Medical Group Association. Lustig, Westrich, and Dubois are employed by the National Pharmaceutical Council, an industry-funded health policy research organization that is not involved in lobbying or advocacy. Study concept and design were contributed by Lustig, Penso, Westrich, and Dubois. Lustig, Ogden, Brenner, and Penso collected the data, and data interpretation was performed by all authors. The manuscript was written primarily by Lustig, along with the other authors, and revised by Lustig, Penso, Westrich, and

  5. Community-Based Rehabilitation of Critical Land at Jenar, Sragen, Central Java

    Directory of Open Access Journals (Sweden)

    Suharjo Suharjo

    2004-01-01

    Full Text Available The aims of the study of critical land rehabitation basing on the society in Jenar Sragen are to know: 1 the factory which cause the critical land; 2 the way to solve critical land; and 3 the role society in solving critical land. The collected date are 1 topography, 2 litologhy, 3 geomorphology, 4 soil, 5 hydrology, 6 land use, 7 the apportion of critical land, and 8 the way to solve critical land. The choice of sample uses purposive method, while the data analysis to get result uses descriptive method. The result of the study show that: 1 the distribution of critical land is in land unit of anticline hills of tuff rocks, marl, clay, and sand tuff which are denudated process by rensina soil and litosol from light to heavy which lie in dry land cultivation and forest. The factors which influence critical land are high rainfall (2178 mm, inclination slope (8 – 20%, solun soil whih is less than 20 cm and denudation process high is active; 2 the way that has been done is solving critical land rehabilitation is cooperation among the society, the forestry and commercial agricultural department and cone sugar factory of Mojo Sragen. The critical land which has been rehabilitated is state forest (266.95 ha and the dry lang cultivation of the society (772.50 ha; 3 the society has responsibility for the growth, the development and preservation of the long term plants (jati, sonokeling, mahoni. The participation of the society in that programme is about 3.117 people.

  6. Randomized controlled resistance training based physical activity trial for central European nursing home residing older adults.

    Science.gov (United States)

    Barthalos, Istvan; Dorgo, Sandor; Kopkáné Plachy, Judit; Szakály, Zsolt; Ihász, Ferenc; Ráczné Németh, Teodóra; Bognár, József

    2016-10-01

    Nursing home residing older adults often experience fear of sickness or death, functional impairment and pain. It is difficult for these older adults to maintain a physically active lifestyle and to keep a positive outlook on life. This study evaluated the changes in quality of life, attitude to aging, assertiveness, physical fitness and body composition of nursing home residing elderly through a 15-week organized resistance training based physical activity program. Inactive older adults living in a state financed nursing home (N.=45) were randomly divided into two intervention groups and a control group. Both intervention groups were assigned to two physical activity sessions a week, but one of these groups also had weekly discussions on health and quality of life (Mental group). Data on anthropometric measures, fitness performance, as well as quality of life and attitudes to aging survey data were collected. Due to low attendance rate 12 subjects were excluded from the analyses. Statistical analysis included Paired Samples t-tests and Repeated Measures Analysis of Variance. Both intervention groups significantly improved their social participation, and their upper- and lower-body strength scores. Also, subjects in the Mental group showed improvement in agility fitness test and certain survey scales. No positive changes were detected in attitude towards aging and body composition measures in any groups. The post-hoc results suggest that Mental group improved significantly more than the Control group. Regular physical activity with discussions on health and quality of life made a more meaningful difference for the older adults living in nursing home than physical activity alone. Due to the fact that all participants were influenced by the program, it is suggested to further explore this area for better understanding of enhanced quality of life.

  7. Mapping of leptospirosis risk factor based on remote sensing image in Tembalang, Semarang City, Central Java

    Directory of Open Access Journals (Sweden)

    Sunaryo Sunaryo

    2012-09-01

    of leptospirosis, physical environment of risk factor analysis.Methods: This cross sectional design consisted of 246 leptospirosis subjects mapped with GPS, and processed by using ArcGis 92 program. Leptospirosis case was overlaid with remote sensing (Quickbird image, then is done interpretation of spatial feature, and digitation on screen to visual identify of risk factor.Results: Based on digital visualization leptospirosis cases in 2009 were clustered in Tembalang with shortest distance index 0,009 km and is furthermost 18 km. More case distribution found at children and men adolescent. Temporally, case increased in the dry season, among of July and August. Result of visual interpretation and digitation can obtain land use map, water body, settlement, fl oods area, vegetation index and height.Conclusion: Spatial high resolution remote sensing image is very good for mapping of leptospirosis risk factor. Leptospirosis case distribution forms the cluster in Tembalang; case is predominated by children andmen adolescent. (Health Science Indones 2012;1:45-50 

  8. A logic-based dynamic modeling approach to explicate the evolution of the central dogma of molecular biology.

    Directory of Open Access Journals (Sweden)

    Mohieddin Jafari

    Full Text Available It is nearly half a century past the age of the introduction of the Central Dogma (CD of molecular biology. This biological axiom has been developed and currently appears to be all the more complex. In this study, we modified CD by adding further species to the CD information flow and mathematically expressed CD within a dynamic framework by using Boolean network based on its present-day and 1965 editions. We show that the enhancement of the Dogma not only now entails a higher level of complexity, but it also shows a higher level of robustness, thus far more consistent with the nature of biological systems. Using this mathematical modeling approach, we put forward a logic-based expression of our conceptual view of molecular biology. Finally, we show that such biological concepts can be converted into dynamic mathematical models using a logic-based approach and thus may be useful as a framework for improving static conceptual models in biology.

  9. A Role for Fragment-Based Drug Design in Developing Novel Lead Compounds for Central Nervous System Targets.

    Science.gov (United States)

    Wasko, Michael J; Pellegrene, Kendy A; Madura, Jeffry D; Surratt, Christopher K

    2015-01-01

    Hundreds of millions of U.S. dollars are invested in the research and development of a single drug. Lead compound development is an area ripe for new design strategies. Therapeutic lead candidates have been traditionally found using high-throughput in vitro pharmacological screening, a costly method for assaying thousands of compounds. This approach has recently been augmented by virtual screening (VS), which employs computer models of the target protein to narrow the search for possible leads. A variant of VS is fragment-based drug design (FBDD), an emerging in silico lead discovery method that introduces low-molecular weight fragments, rather than intact compounds, into the binding pocket of the receptor model. These fragments serve as starting points for "growing" the lead candidate. Current efforts in virtual FBDD within central nervous system (CNS) targets are reviewed, as is a recent rule-based optimization strategy in which new molecules are generated within a 3D receptor-binding pocket using the fragment as a scaffold. This process not only places special emphasis on creating synthesizable molecules but also exposes computational questions worth addressing. Fragment-based methods provide a viable, relatively low-cost alternative for therapeutic lead discovery and optimization that can be applied to CNS targets to augment current design strategies.

  10. Performance of medical residents in sterile techniques during central vein catheterization: randomized trial of efficacy of simulation-based training.

    Science.gov (United States)

    Khouli, Hassan; Jahnes, Katherine; Shapiro, Janet; Rose, Keith; Mathew, Joseph; Gohil, Amit; Han, Qifa; Sotelo, Andre; Jones, James; Aqeel, Adnan; Eden, Edward; Fried, Ethan

    2011-01-01

    Catheter-related bloodstream infection (CRBSI) is a preventable cause of a potentially lethal ICU infection. The optimal method to teach health-care providers correct sterile techniques during central vein catheterization (CVC) remains unclear. We randomly assigned second- and third-year internal medicine residents trained by a traditional apprenticeship model to simulation-based plus video training or video training alone from December 2007 to January 2008, with a follow-up period to examine CRBSI ending in July 2009. During the follow-up period, a simulation-based training program in sterile techniques during CVC was implemented in the medical ICU (MICU). A surgical ICU (SICU) where no residents received study interventions was used for comparison. The primary outcome measures were median residents' scores in sterile techniques and rates of CRBSI per 1,000 catheter-days. Of the 47 enrolled residents, 24 were randomly assigned to the simulation-based plus video training group and 23 to the video training group. Median baseline scores in both groups were equally poor: 12.5 to 13 (52%-54%) out of maximum score of 24 (P = .95; median difference, 0; 95% CI, 0.2-2.0). After training, median score was significantly higher for the simulation-based plus video training group: 22 (92%) vs 18 (75%) for the video training group (P training in sterile techniques during CVC is superior to traditional training or video training alone and is associated with decreased rate of CRBSI. Simulation-based training in CVC should be routinely used to reduce iatrogenic risk. ClinicalTrials.gov; No.: NCT00612131; URL: clinicaltrials.gov.

  11. Reconstruction of Oceanographic Changes Based on the Diatom Records of the Central Okhotsk Sea over the last 500000 Years

    Directory of Open Access Journals (Sweden)

    Wei-Lung Wang Liang-Chi Wang

    2008-01-01

    Full Text Available This study provides insight into changes in sea ice conditions and the oceanographic environment over the past 500 kyr through analysis of the diatom record. Based on the relative abundance of 13 diatoms species in piston core MD012414, four types of environmental conditions in the central Okhotsk Sea over the last 330 ka BP have been distinguished: (1 open-ocean alternating with seasonal sea-ice cover in Stages 9, 5, and 1; (2 almost open-ocean free of sea-ice cover in Stages 7 and 3; (3 perennial sea-ice cover in Stages 6, 4, and 2; and (4 a warm ice-age dominated by open ocean assemblages in Stage 8. The littoral diatom species, Paralia sulcata, showed a sudden increase from the glacial period to the nterglacial period over the last 330 ka BP, except during Stage 8. Such a result implies that melting sea-ice transported terrigenous materials from the north Okhotsk Sea continental shelves to the central ocean during eglaciation. From Stage 13 to Stage 10, however, cold and warm marine conditions unexpectedly occurred in the late interglacial periods and the glacial periods, respectively. One possible reason for this is a lack of age control points from Stage 13 to Stage 10, and the different sediment accumulation rates between glacial and interglacial periods. This study suggests not only the process by which oceanographic variation of sea ice occurred, but also new significance for Paralia sulcata as an indicator in the diatom record of the Okhotsk Sea.

  12. Shale gas characterization based on geochemical and geophysical analysis: Case study of Brown shale, Pematang formation, Central Sumatra Basin

    Science.gov (United States)

    Haris, A.; Nastria, N.; Soebandrio, D.; Riyanto, A.

    2017-07-01

    Geochemical and geophysical analyses of shale gas have been carried out in Brown Shale, Middle Pematang Formation, Central Sumatra Basin. The paper is aimed at delineating the sweet spot distribution of potential shale gas reservoir, which is based on Total Organic Carbon (TOC), Maturity level data, and combined with TOC modeling that refers to Passey and Regression Multi Linear method. We used 4 well data, side wall core and 3D pre-stack seismic data. Our analysis of geochemical properties is based on well log and core data and its distribution are constrained by a framework of 3D seismic data, which is transformed into acoustic impedance. Further, the sweet spot of organic-rich shale is delineated by mapping TOC, which is extracted from inverted acoustic impedance. Our experiment analysis shows that organic materials contained in the formation of Middle Pematang Brown Shale members have TOC range from 0.15 to 2.71 wt.%, which is classified in the quality of poor to very good. In addition, the maturity level of organic material is ranging from 373°C to 432°C, which is indicated by vitrinite reflectance (Ro) of 0.58. In term of kerogen type, this Brown shale formation is categorized as kerogen type of II I III, which has the potential to generate a mixture of gasIoil on the environment.

  13. Increased incidence of peptic ulcer disease in central serous chorioretinopathy patients: a population-based retrospective cohort study.

    Science.gov (United States)

    Chen, San-Ni; Lian, Iebin; Chen, Yi-Chiao; Ho, Jau-Der

    2015-02-01

    To investigate peptic ulcer disease and other possible risk factors in patients with central serous chorioretinopathy (CSR) using a population-based database. In this population-based retrospective cohort study, longitudinal data from the Taiwan National Health Insurance Research Database were analyzed. The study cohort comprised 835 patients with CSR and the control cohort comprised 4175 patients without CSR from January 2000 to December 2009. Conditional logistic regression was applied to examine the association of peptic ulcer disease and other possible risk factors for CSR, and stratified Cox regression models were applied to examine whether patients with CSR have an increased chance of peptic ulcer disease and hypertension development. The identifiable risk factors for CSR included peptic ulcer disease (adjusted odd ratio: 1.39, P = 0.001) and higher monthly income (adjusted odd ratio: 1.30, P = 0.006). Patients with CSR also had a significantly higher chance of developing peptic ulcer disease after the diagnosis of CSR (adjusted odd ratio: 1.43, P = 0.009). Peptic ulcer disease and higher monthly income are independent risk factors for CSR. Whereas, patients with CSR also had increased risk for peptic ulcer development.

  14. The Effect of Model Fidelity on Learning Outcomes of a Simulation-Based Education Program for Central Venous Catheter Insertion.

    Science.gov (United States)

    Diederich, Emily; Mahnken, Jonathan D; Rigler, Sally K; Williamson, Timothy L; Tarver, Stephen; Sharpe, Matthew R

    2015-12-01

    Simulation-based education for central venous catheter (CVC) insertion has been repeatedly documented to improve performance, but the impact of simulation model fidelity has not been described. The aim of this study was to examine the impact of the physical fidelity of the simulation model on learning outcomes for a simulation-based education program for CVC insertion. Forty consecutive residents rotating through the medical intensive care unit of an academic medical center completed a simulation-based education program for CVC insertion. The curriculum was designed in accordance with the principles of deliberate practice and mastery learning. Each resident underwent baseline skills testing and was then randomized to training on a commercially available CVC model with high physical fidelity (High-Fi group) or a simply constructed model with low physical fidelity (Low-Fi group) in a noninferiority trial. Upon completion of their medical intensive care unit rotation 4 weeks later, residents returned for repeat skills testing on the high-fidelity model using a 26-item checklist. The mean (SD) posttraining score on the 26-item checklist for the Low-Fi group was 23.8 (2.2) (91.5%) and was not inferior to the mean (SD) score for the High-Fi group of 22.5 (2.6) (86.5%) (P Simulation-based education using equipment with low physical fidelity can achieve learning outcomes comparable with those with high-fidelity equipment, as long as other aspects of fidelity are maintained and robust educational principles are applied during the design of the curriculum.

  15. Use of simulation-based education to improve outcomes of central venous catheterization: a systematic review and meta-analysis.

    Science.gov (United States)

    Ma, Irene W Y; Brindle, Mary E; Ronksley, Paul E; Lorenzetti, Diane L; Sauve, Reg S; Ghali, William A

    2011-09-01

    Central venous catheterization (CVC) is increasingly taught by simulation. The authors reviewed the literature on the effects of simulation training in CVC on learner and clinical outcomes. The authors searched computerized databases (1950 to May 2010), reference lists, and considered studies with a control group (without simulation education intervention). Two independent assessors reviewed the retrieved citations. Independent data abstraction was performed on study design, study quality score, learner characteristics, sample size, components of interventional curriculum, outcomes assessed, and method of assessment. Learner outcomes included performance measures on simulators, knowledge, and confidence. Patient outcomes included number of needle passes, arterial puncture, pneumothorax, and catheter-related infections. Twenty studies were identified. Simulation-based education was associated with significant improvements in learner outcomes: performance on simulators (standardized mean difference [SMD] 0.60 [95% CI 0.45 to 0.76]), knowledge (SMD 0.60 [95% CI 0.35 to 0.84]), and confidence (SMD 0.41 [95% CI 0.30 to 0.53] for studies with single-group pretest and posttest design; SMD 0.52 (95% CI 0.23 to 0.81) for studies with nonrandomized, two-group design). Furthermore, simulation-based education was associated with improved patient outcomes, including fewer needle passes (SMD -0.58 [95% CI -0.95 to -0.20]), and pneumothorax (relative risk 0.62 [95% CI 0.40 to 0.97]), for studies with nonrandomized, two-group design. However, simulation-based training was not associated with a significant reduction in risk of either arterial puncture or catheter-related infections. Despite some limitations in the literature reviewed, evidence suggests that simulation-based education for CVC provides benefits in learner and select clinical outcomes.

  16. Centrality based Document Ranking

    Science.gov (United States)

    2014-11-01

    support task. As it turned out, the results were very poor, which suggests that using a general purpose IR sytem in this way is not a good idea... Management on the Semantic Web, 2005. 15. P. Mika, T. Tudorache, A. Bernstein, C. Welty, C. A. Knoblock, D. Vrandecic, P. T. Groth, N. F. Noy, K. Janowicz...question- focused sentence retrieval. In HLT ’05: Proceedings of the conference on Hu- man Language Technology and Empirical Methods in Natural

  17. Image based Monument Recognition using Graph based Visual Saliency

    DEFF Research Database (Denmark)

    Kalliatakis, Grigorios; Triantafyllidis, Georgios

    2013-01-01

    This article presents an image-based application aiming at simple image classification of well-known monuments in the area of Heraklion, Crete, Greece. This classification takes place by utilizing Graph Based Visual Saliency (GBVS) and employing Scale Invariant Feature Transform (SIFT) or Speeded......, the images have been previously processed according to the Graph Based Visual Saliency model in order to keep either SIFT or SURF features corresponding to the actual monuments while the background “noise” is minimized. The application is then able to classify these images, helping the user to better...

  18. Cuff-Based Oscillometric Central and Brachial Blood Pressures Obtained Through ABPM are Similarly Associated with Renal Organ Damage in Arterial Hypertension

    Directory of Open Access Journals (Sweden)

    Patricia Fernández-Llama

    2017-12-01

    Full Text Available Background/Aims: Central blood pressure (BP has been suggested to be a better estimator of hypertension-associated risks. We aimed to evaluate the association of 24-hour central BP, in comparison with 24-hour peripheral BP, with the presence of renal organ damage in hypertensive patients. Methods: Brachial and central (calculated by an oscillometric system through brachial pulse wave analysis office BP and ambulatory BP monitoring (ABPM data and aortic pulse wave velocity (PWV were measured in 208 hypertensive patients. Renal organ damage was evaluated by means of the albumin to creatinine ratio and the estimated glomerular filtration rate. Results: Fifty-four patients (25.9% were affected by renal organ damage, displaying either microalbuminuria (urinary albumin excretion ≥30 mg/g creatinine or an estimated glomerular filtration rate (eGFR <60 ml/min/1.73 m2. Compared to those without renal abnormalities, hypertensive patients with kidney damage had higher values of office brachial systolic BP (SBP and pulse pressure (PP, and 24-h, daytime, and nighttime central and brachial SBP and PP. They also had a blunted nocturnal decrease in both central and brachial BP, and higher values of aortic PWV. After adjustment for age, gender, and antihypertensive treatment, only ABPM-derived BP estimates (both central and brachial showed significant associations with the presence of renal damage. Odds ratios for central BP estimates were not significantly higher than those obtained for brachial BP. Conclusion: Compared with peripheral ABPM, cuff-based oscillometric central ABPM does not show a closer association with presence of renal organ damage in hypertensive patients. More studies, however, need to be done to better identify the role of central BP in clinical practice.

  19. Cuff-Based Oscillometric Central and Brachial Blood Pressures Obtained Through ABPM are Similarly Associated with Renal Organ Damage in Arterial Hypertension.

    Science.gov (United States)

    Fernández-Llama, Patricia; Pareja, Júlia; Yun, Sergi; Vázquez, Susana; Oliveras, Anna; Armario, Pedro; Blanch, Pedro; Calero, Francesca; Sierra, Cristina; de la Sierra, Alejandro

    2017-01-01

    Central blood pressure (BP) has been suggested to be a better estimator of hypertension-associated risks. We aimed to evaluate the association of 24-hour central BP, in comparison with 24-hour peripheral BP, with the presence of renal organ damage in hypertensive patients. Brachial and central (calculated by an oscillometric system through brachial pulse wave analysis) office BP and ambulatory BP monitoring (ABPM) data and aortic pulse wave velocity (PWV) were measured in 208 hypertensive patients. Renal organ damage was evaluated by means of the albumin to creatinine ratio and the estimated glomerular filtration rate. Fifty-four patients (25.9%) were affected by renal organ damage, displaying either microalbuminuria (urinary albumin excretion ≥30 mg/g creatinine) or an estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m2. Compared to those without renal abnormalities, hypertensive patients with kidney damage had higher values of office brachial systolic BP (SBP) and pulse pressure (PP), and 24-h, daytime, and nighttime central and brachial SBP and PP. They also had a blunted nocturnal decrease in both central and brachial BP, and higher values of aortic PWV. After adjustment for age, gender, and antihypertensive treatment, only ABPM-derived BP estimates (both central and brachial) showed significant associations with the presence of renal damage. Odds ratios for central BP estimates were not significantly higher than those obtained for brachial BP. Compared with peripheral ABPM, cuff-based oscillometric central ABPM does not show a closer association with presence of renal organ damage in hypertensive patients. More studies, however, need to be done to better identify the role of central BP in clinical practice. © 2017 The Author(s). Published by S. Karger AG, Basel.

  20. Application of a process-based shallow landslide hazard model over a broad area in Central Italy

    Science.gov (United States)

    Gioia, Eleonora; Speranza, Gabriella; Ferretti, Maurizio; Godt, Jonathan W.; Baum, Rex L.; Marincioni, Fausto

    2015-01-01

    Process-based models are widely used for rainfall-induced shallow landslide forecasting. Previous studies have successfully applied the U.S. Geological Survey’s Transient Rainfall Infiltration and Grid-Based Regional Slope-Stability (TRIGRS) model (Baum et al. 2002) to compute infiltration-driven changes in the hillslopes’ factor of safety on small scales (i.e., tens of square kilometers). Soil data input for such models are difficult to obtain across larger regions. This work describes a novel methodology for the application of TRIGRS over broad areas with relatively uniform hydrogeological properties. The study area is a 550-km2 region in Central Italy covered by post-orogenic Quaternary sediments. Due to the lack of field data, we assigned mechanical and hydrological property values through a statistical analysis based on literature review of soils matching the local lithologies. We calibrated the model using rainfall data from 25 historical rainfall events that triggered landslides. We compared the variation of pressure head and factor of safety with the landslide occurrence to identify the best fitting input conditions. Using calibrated inputs and a soil depth model, we ran TRIGRS for the study area. Receiver operating characteristic (ROC) analysis, comparing the model’s output with a shallow landslide inventory, shows that TRIGRS effectively simulated the instability conditions in the post-orogenic complex during historical rainfall scenarios. The implication of this work is that rainfall-induced landslides over large regions may be predicted by a deterministic model, even where data on geotechnical and hydraulic properties as well as temporal changes in topography or subsurface conditions are not available.

  1. CENTRAL WAVELENGTH ADJUSTMENT OF LIGHT EMITTING SOURCE IN INTERFEROMETRIC SENSORS BASED ON FIBER-OPTIC BRAGG GRATINGS

    Directory of Open Access Journals (Sweden)

    A. S. Aleynik

    2015-09-01

    Full Text Available The paper is focused on the investigation of fiber-optic interferometric sensor based on the array of fiber Bragg gratings. Reflection spectra displacement mechanism of the fiber Bragg gratings under the external temperature effects and the static pressure is described. The experiment has shown that reflection spectra displacement of Bragg gratings reduces the visibility of the interference pattern. A method of center wavelength adjustment is proposed for the optical radiation source in accord ance with the current Bragg gratings reflection spectra based on the impulse relative modulation of control signal for the Peltier element controller. The semiconductor vertical-cavity surface-emitting laser controlled by a pump driver is used as a light source. The method is implemented by the Peltier element controller regulating and stabilizing the light source temperature, and a programmable logic-integrated circuit monitoring the Peltier element controller. The experiment has proved that the proposed method rendered possible to regulate the light source temperature at a pitch of 0.05 K and adjust the optical radiation source center wavelength at a pitch of 0.05 nm. Experimental results have revealed that the central wavelength of the radiation adjustment at a pitch of 0.005 nm gives the possibility for the capacity of the array consisting of four opticalfiber sensors based on the fiber Bragg gratings. They are formed in one optical fiber under the Bragg grating temperature change from 0° C to 300° C and by the optical fiber mechanical stretching by the force up to 2 N.

  2. GC×GC measurements of C7-C11 aromatic and n-alkane hydrocarbons on Crete, in air from Eastern Europe during the MINOS campaign

    Directory of Open Access Journals (Sweden)

    X. Xu

    2003-01-01

    Full Text Available During the Mediterranean Intensive Oxidant Study (MINOS campaign in August 2001 gas-phase organic compounds were measured using comprehensive two-dimensional gas chromatography (GCxGC at the Finokalia ground station, Crete. In this paper, C7-C11 aromatic and n-alkane measurements are presented and interpreted. The mean mixing ratios of the hydrocarbons varied from 1±1 pptv (i-propylbenzene to 43±36 pptv (toluene. The observed mixing ratios showed strong day-to-day variations and generally higher levels during the first half of the campaign. Mean diel profiles showed maxima at local midnight and late morning, and minima in the early morning and evening. Results from analysis using a simplified box model suggest that both the chemical sink (i.e. reaction with OH and the variability of source strengths were the causes of the observed variations in hydrocarbon mixing ratios. The logarithms of hydrocarbon concentrations were negatively correlated with the OH concentrations integral over a day prior to the hydrocarbon measurements. Slopes of the regression lines derived from these correlations for different compounds are compared with literature rate constants for their reactions with OH. The slopes for most compounds agree reasonably well with the literature rate constants. A sequential reaction model has been applied to the interpretation of the relationship between ethylbenzene and two of its potential products, i.e. acetophenone and benzeneacetaldehyde. The model can explain the good correlation observed between [acetophenone]/[ethylbenzene] and [benzeneacetaldehyde]/[ethylbenzene]. The model results and field measurements suggest that the reactivity of benzeneacetaldehyde may lie between those of acetophenone and ethylbenzene and that the ratio between yields of acetophenone and benzeneacetaldehyde may be up to 28:1. Photochemical ages of trace gases sampled at Finokalia during the campaign are estimated using the sequential reaction model and

  3. GC×GC measurements of C7-C11 aromatic and n-alkane hydrocarbons on Crete, in air from Eastern Europe during the MINOS campaign

    Science.gov (United States)

    Xu, X.; Williams, C.; Plass-Dülmer, H.; Berresheim, H.; Salisbury, G.; Lange, L.; Lelieveld, J.

    2003-09-01

    During the Mediterranean Intensive Oxidant Study (MINOS) campaign in August 2001 gas-phase organic compounds were measured using comprehensive two-dimensional gas chromatography (GCxGC) at the Finokalia ground station, Crete. In this paper, C7-C11 aromatic and n-alkane measurements are presented and interpreted. The mean mixing ratios of the hydrocarbons varied from 1±1 pptv (i-propylbenzene) to 43±36 pptv (toluene). The observed mixing ratios showed strong day-to-day variations and generally higher levels during the first half of the campaign. Mean diel profiles showed maxima at local midnight and late morning, and minima in the early morning and evening. Results from analysis using a simplified box model suggest that both the chemical sink (i.e. reaction with OH) and the variability of source strengths were the causes of the observed variations in hydrocarbon mixing ratios. The logarithms of hydrocarbon concentrations were negatively correlated with the OH concentrations integral over a day prior to the hydrocarbon measurements. Slopes of the regression lines derived from these correlations for different compounds are compared with literature rate constants for their reactions with OH. The slopes for most compounds agree reasonably well with the literature rate constants. A sequential reaction model has been applied to the interpretation of the relationship between ethylbenzene and two of its potential products, i.e. acetophenone and benzeneacetaldehyde. The model can explain the good correlation observed between [acetophenone]/[ethylbenzene] and [benzeneacetaldehyde]/[ethylbenzene]. The model results and field measurements suggest that the reactivity of benzeneacetaldehyde may lie between those of acetophenone and ethylbenzene and that the ratio between yields of acetophenone and benzeneacetaldehyde may be up to 28:1. Photochemical ages of trace gases sampled at Finokalia during the campaign are estimated using the sequential reaction model and related data

  4. A parameter-free community detection method based on centrality and dispersion of nodes in complex networks

    Science.gov (United States)

    Li, Yafang; Jia, Caiyan; Yu, Jian

    2015-11-01

    K-means is a simple and efficient clustering algorithm to detect communities in networks. However, it may suffer from a bad choice of initial seeds (also called centers) that seriously affect the clustering accuracy and the convergence rate. Additionally, in K-means, the number of communities should be specified in advance. Till now, it is still an open problem on how to select initial seeds and how to determine the number of communities. In this study, a new parameter-free community detection method (named K-rank-D) was proposed. First, based on the fact that good initial seeds usually have high importance and are dispersedly located in a network, we proposed a modified PageRank centrality to evaluate the importance of a node, and drew a decision graph to depict the importance and the dispersion of nodes. Then, the initial seeds and the number of communities were selected from the decision graph actively and intuitively as the 'start' parameter of K-means. Experimental results on synthetic and real-world networks demonstrate the superior performance of our approach over competing methods for community detection.

  5. A pollen-based reconstruction of summer temperature in central North America and implications for circulation patterns during medieval times

    Science.gov (United States)

    Wahl, Eugene R.; Diaz, Henry F.; Ohlwein, Christian

    2012-03-01

    We present a reconstruction of mean summer temperature for the northern Midwest of the USA based on lacustrine pollen records from three different lakes in Wisconsin. The results suggest a relatively warm period during the earlier part of the record (~ 1200-1500 CE) followed by a cooler Little Ice Age (~ 1500-1900) and a subsequent warming to modern conditions. The reconstructed modern summer mean temperature is in good agreement with observations, and the decades of the 1930s to 1950s appear to be the warmest such period in the proxy record (through 1974). Analyses of circulation features associated with the warmest summers in the recent climate record suggest a prevalence of continental ridging accompanied by generally dry conditions during these warm summers in the Midwest. Drought reconstruction using the Palmer Drought Severity Index (PDSI) and tree-ring records as predictors also yield relatively dry conditions in medieval times for the central US. As reported in a number of recent studies, possible forcing mechanisms include La Niña-like conditions in the equatorial Pacific and warmer than average waters in the tropical Indo-western Pacific Ocean possibly coupled to a positive mode of the AMO/NAO North Atlantic circulation pattern.

  6. Determinants of Cervical Cancer Screening Uptake among Women in Ilorin, North Central Nigeria: A Community-Based Study

    International Nuclear Information System (INIS)

    Idowu, A.; Olowookere, S. A.; Fagbemi, A.T.; Ogunlaja, O. A.

    2016-01-01

    Cancer of the cervix is the leading cause of cancer deaths among women in developing countries. Screening is one of the most cost effective control strategies for the disease. This study assessed the determinants of cervical cancer screening uptake among Nigerian women. Methodology. This cross-sectional study was conducted using multistage sampling technique among 338 participants in Ilorin, North Central Nigeria. A pretested questionnaire was used for data collection and data analysis was done using SPSS version 21. Chi-square test was used for bivariate analysis while binary logistic regression was used for multivariate analysis. Statistical significance was set at P<0.05. Results. Only 8.0% of the respondents had ever been screened for cancer of the cervix. The proportion of women who had ever been screened was significantly higher among those who demonstrated positive attitude to screening (81.5%, P= 0.001), respondents who were aware of the disease (100.0%, p=0.001), and those who were aware of cervical cancer screening (88.9%, P=0.001). Respondents who had negative attitude had 63% lesser odds of being screened compared to those who had positive attitudes towards screening (AOR; 0.37, 95% CI; 0.0-0.28). Conclusion. There is urgent need to improve the knowledge base and attitude of Nigerian women to enhance cervical cancer screening uptake among them.

  7. Anterolateral corridor approach to the infratemporal fossa and central skull base in maxillectomy: rationale and technical aspects.

    Science.gov (United States)

    McMahon, Jeremy D; Crowther, John; Taylor, William M; Wong, Ling Siew; Paterson, Tom; Devine, John; Wales, Craig; MacIver, Colin

    2015-11-01

    We describe the technical aspects and report our clinical experience of a surgical approach to the infratemporal fossa that aims to reduce local recurrence after operations for cancer of the posterior maxilla. We tested the technique by operating on 3 cadavers and then used the approach in 16 patients who had posterolateral maxillectomy for disease that arose on the maxillary alveolus or junction of the hard and soft palate (maxillary group), and in 19 who had resection of the masticatory compartment and central skull base for advanced sinonasal cancer (sinonasal group). Early proximal ligation of the maxillary artery was achieved in all but one of the 35 patients. Access to the infratemporal fossa enabled division of the pterygoid muscles and pterygoid processes under direct vision in all cases. No patient in the maxillary group had local recurrence at median follow up of 36 months. Four patients (21%) in the sinonasal group had local recurrence at median follow up of 27 months. Secondary haemorrhage from the cavernous segment of the internal carotid artery resulted in the only perioperative death. The anterolateral corridor approach enables controlled resection of tumours that extend into the masticatory compartment. Copyright © 2015 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  8. Application of modelling and nanotechnology-based approaches: The emergence of breakthroughs in theranostics of central nervous system disorders.

    Science.gov (United States)

    Hassanzadeh, Parichehr; Atyabi, Fatemeh; Dinarvand, Rassoul

    2017-08-01

    The limited efficiency of the current treatment options against the central nervous system (CNS) disorders has created increasing demands towards the development of novel theranostic strategies. The enormous research efforts in nanotechnology have led to the production of highly-advanced nanodevices and biomaterials in a variety of geometries and configurations for targeted delivery of genes, drugs, or growth factors across the blood-brain barrier. Meanwhile, the richness or reliability of data, drug delivery methods, therapeutic effects or potential toxicity of nanoparticles, occurrence of the unexpected phenomena due to the polydisperse or polymorphic nature of nanomaterials, and personalized theranostics have remained as challenging issues. In this respect, computational modelling has emerged as a powerful tool for rational design of nanoparticles with optimized characteristics including the selectivity, improved bioactivity, and reduced toxicity that might lead to the effective delivery of therapeutic agents. High-performance simulation techniques by shedding more light on the dynamical behaviour of neural networks and pathomechanisms of CNS disorders may provide imminent breakthroughs in nanomedicine. In the present review, the importance of integration of nanotechnology-based approaches with computational techniques for targeted delivery of theranostics to the CNS has been highlighted. Copyright © 2017. Published by Elsevier Inc.

  9. Controlling Aedes aegypti population as DHF vector with radiation based-sterile insect technique in Banjarnegara Regency, Central Java

    International Nuclear Information System (INIS)

    Siti Nurhayati; Bambang Yunianto; Tri Ramadhani; Bina Ikawati; Budi Santoso; Ali Rahayu

    2013-01-01

    The control program of dengue hemorrhagic fever (DHF) in Indonesia is still a problem due to the incomplete integrated handling. Sterile insect technique (SIT) for Aedes aegypti as DHF vector was considered as a potential strategy for controlling the DHF. A preliminary survey was carried out to determine the characteristic of A aegypti population in the study site before the implementation of SIT. The implementation of radiation based-SIT was carried out in Krandegan and Kutabanjar Villages of Banjarnegara Regency, Central Java which involved 99 houses. One hundred gamma rays irradiated male mosquitoes were released to each house up to five times. The eggs, larvae and adult mosquitoes were collected using ovitrap and weekly observed. The initial population density of A. aegypti in the studied area was obtained to be 6 mosquitoes per house with the mean index of house was 15.86% and the mean sterility of sterilized mosquitoes was 79.16%. The SIT effectively reduced A. aegypti population after the fifth release of irradiated mosquitoes into the houses. It can be assumed that the SIT was effective in controlling DHF vector in the studied area, nevertheless, it will be more effective if it is combined with other handling techniques. (author)

  10. An Abattoir-Based Study on Serodiagnosis of Swine Brucellosis in Makurdi, Benue State, North-Central Nigeria

    Directory of Open Access Journals (Sweden)

    Emmanuel Ochefije Ngbede

    2013-04-01

    Full Text Available An abattoir serological survey of brucellosis in pigs was conducted in Makurdi, Benue State North Central Nigeria between October and November 2011. Blood-sera were collected from a total of 281 slaughtered pigs and their ages and sex were recorded. The sera were tested for brucellosis using the Rose Bengal Plate Test (RBPT. A total of 86 of the 281 (30.60% pigs were serologically positive. The prevalence of positive pigs based on sex was 31.20% and 30.13% for male and female pigs, respectively. The age prevalence was 30.10% and 32.00% for young and adult pigs, respectively. There was no statistically significant association (p>0.05 between positivity of reactor pigs and their sex or age. This study concluded that brucellosis is a problem in the swine industry. Consequently, strict sanitary measures and control of swine brucellosis is urgently warranted to avoid spread of infection through pigs’ populations and their contacted persons as well as pork consumers.

  11. Determinants of Cervical Cancer Screening Uptake among Women in Ilorin, North Central Nigeria: A Community-Based Study

    Directory of Open Access Journals (Sweden)

    Ajibola Idowu

    2016-01-01

    Full Text Available Introduction. Cancer of the cervix is the leading cause of cancer deaths among women in developing countries. Screening is one of the most cost effective control strategies for the disease. This study assessed the determinants of cervical cancer screening uptake among Nigerian women. Methodology. This cross-sectional study was conducted using multistage sampling technique among 338 participants in Ilorin, North Central Nigeria. A pretested questionnaire was used for data collection and data analysis was done using SPSS version 21. Chi-square test was used for bivariate analysis while binary logistic regression was used for multivariate analysis. Statistical significance was set at p<0.05. Results. Only 8.0% of the respondents had ever been screened for cancer of the cervix. The proportion of women who had ever been screened was significantly higher among those who demonstrated positive attitude to screening (81.5%, p=0.001, respondents who were aware of the disease (100.0%, p=0.001, and those who were aware of cervical cancer screening (88.9%, p=0.001. Respondents who had negative attitude had 63% lesser odds of being screened compared to those who had positive attitudes towards screening (AOR; 0.37, 95% CI; 0.01–0.28. Conclusion. There is urgent need to improve the knowledge base and attitude of Nigerian women to enhance cervical cancer screening uptake among them.

  12. First results of tall tower based nitrous oxide flux monitoring over an agricultural region in Central Europe

    Science.gov (United States)

    Haszpra, László; Hidy, Dóra; Taligás, Tímea; Barcza, Zoltán

    2018-03-01

    Nitrous oxide is one of the atmospheric greenhouse gases whose amount is significantly influenced by human activity. Its major anthropogenic sources are the agricultural soils but the emission is known only with large uncertainty yet. The paper presents a tall tower based measuring system installed in Hungary, which is designed for the long-term monitoring of nitrous oxide emission of a regionally typical composition of agricultural fields by means of eddy covariance technique. Due to the careful calibration of the gas analyzer applied the measuring system is also suitable for the recording of the atmospheric concentration of nitrous oxide on the globally compatible scale (WMO X2006A). The paper reports the results of the first two years of the monitoring program, which is the first of its kind in Central Europe. For the period of July 2015-June 2017 the concentration measurements indicate an increasing trend of 0.91 nmol mol-1 year-1 with an average concentration of 330.64 nmol mol-1. During the two years of the project, the monitoring system recorded a total of 441 ± 195 mg N2O-N m-2 nitrous oxide emission with late spring/early summer maximum. The measurements also revealed the episodic nature of the emission typically triggered by major precipitation events.

  13. GIS-based landslide susceptibility mapping models applied to natural and urban planning in Trikala, Central Greece

    Energy Technology Data Exchange (ETDEWEB)

    Bathrellos, G. D.; Kalivas, D. P.; Skilodimou, H. D.

    2009-07-01

    Landslide susceptibility mapping is a practical tool in natural and urban planning; it can be applied for determining land use zones, in construction design and planning of a variety of projects. In this study, two different GIS based landslide susceptibility maps were generated in the mountainous part of the Trikala Prefecture in Thessaly, Central Greece. This was accomplished by using different methods for correlating factors, which have an effect on landslide occurrences. The instability factors taken into account were: lithology, tectonic features, slope gradients, road network, drainage network, land use and rainfall. A frequency distribution of the half number of the landslide events of the study area in each class of the instability factors was performed in order to rate the classes. Two models have been used to combine the instability factors and assess the overall landslide susceptibility, namely: the Weight Factor Model (WeF), which is a statistical method, and the Multiple Factor Model (MuF) that is a logical method. The produced maps were classified into four zones: Low, Moderate, High and Very High susceptible zones and validated using the other half number of the landslide events of the area. Evaluation of the results is optimized through a Landslide Models Indicator (La.M.I.). (Author) 36 refs.

  14. Rare earth elements in street dust and associated health risk in a municipal industrial base of central China.

    Science.gov (United States)

    Sun, Guangyi; Li, Zhonggen; Liu, Ting; Chen, Ji; Wu, Tingting; Feng, Xinbin

    2017-12-01

    The content levels, distribution characteristics, and health risks associated with 15 rare earth elements (REEs) in urban street dust from an industrial city, Zhuzhou, in central China were investigated. The total REE content (∑REE) ranged from 66.1 to 237.4 mg kg -1 , with an average of 115.9 mg kg -1 , which is lower than that of Chinese background soil and Yangtze river sediment. Average content of the individual REE in street dust decreased in the order Ce > La > Nd > Y > Pr > Sm > Gd > Dy > Er > Yb > Eu > Ho > Tb > Tm > Lu. The chondrite-normalized REE pattern indicated light REE (LREE) enrichment, a relatively steep LREE trend, heavy REE (HREE) depletion, a flat HREE trend, a Eu-negative anomaly and a Ce-positive anomaly. Foremost heavy local soil and to less degree anthropogenic pollution are the main sources of REE present in street dust. Health risk associated with the exposure of REE in street dust was assessed based on the carcinogenic and non-carcinogenic effect and lifetime average daily dose. The obtained cancer and non-cancer risk values prompt for no augmented health hazard. However, children had greater health risks than that of adults.

  15. Characterisation of Central-African emissions based on MAX-DOAS measurements, satellite observations and model simulations over Bujumbura, Burundi.

    Science.gov (United States)

    Gielen, Clio; Hendrick, Francois; Pinardi, Gaia; De Smedt, Isabelle; Stavrakou, Trissevgeni; Yu, Huan; Fayt, Caroline; Hermans, Christian; Bauwens, Maité; Ndenzako, Eugene; Nzohabonayo, Pierre; Akimana, Rachel; Niyonzima, Sébastien; Müller, Jean-Francois; Van Roozendael, Michel

    2016-04-01

    Central Africa is known for its strong biogenic, pyrogenic, and to a lesser extent anthropogenic emissions. Satellite observations of species like nitrogen dioxide (NO2) and formaldehyde (HCHO), as well as inverse modelling results have shown that there are large uncertainties associated with the emissions in this region. There is thus a need for additional measurements, especially from the ground, in order to better characterise the biomass-burning and biogenic products emitted in this area. We present MAX-DOAS measurements of NO2, HCHO, and aerosols performed in Central Africa, in the city of Bujumbura, Burundi (3°S, 29°E, 850m). A MAX-DOAS instrument has been operating at this location by BIRA-IASB since late 2013. Aerosol-extinction and trace-gases vertical profiles are retrieved by applying the optimal-estimation-based profiling tool bePRO to the measured O4, NO2 and HCHO slant-column densities. The MAX-DOAS vertical columns and profiles are used for investigating the diurnal and seasonal cycles of NO2, HCHO, and aerosols. Regarding the aerosols, the retrieved AODs are compared to co-located AERONET sun photometer measurements for verification purpose, while in the case of NO2 and HCHO, the MAX-DOAS vertical columns and profiles are used for validating GOME-2 and OMI satellite observations. To characterise the biomass-burning and biogenic emissions in the Bujumbura region, the trace gases and aerosol MAX-DOAS retrievals are used in combination to MODIS fire counts/radiative-power and GOME-2/OMI NO2 and HCHO satellite data, as well as simulations from the NOAA backward trajectory model HYSPLIT. First results show that HCHO seasonal variation around local noon is driven by the alternation of rain and dry periods, the latter being associated with intense biomass-burning agricultural activities and forest fires in the south/south-east and transport from this region to Bujumbura. In contrast, NO2 is seen to depend mainly on local emissions close to the city, due

  16. Nanoparticle-based drug delivery to improve the efficacy of antiretroviral therapy in the central nervous system

    Directory of Open Access Journals (Sweden)

    Gomes MJ

    2014-04-01

    Full Text Available Maria João Gomes,1 José das Neves,1,2 Bruno Sarmento1,2 1Instituto de Engenharia Biomédica (INEB, Porto, Portugal; 2Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde (IINFACTS, Instituto Superior de Ciências da Saúde-Norte, CESPU, Gandra, Portugal Abstract: Antiretroviral drug therapy plays a cornerstone role in the treatment of human immunodeficiency virus (HIV/acquired immunodeficiency syndrome patients. Despite obvious advances over the past 3 decades, new approaches toward improved management of infected individuals are still required. Drug distribution to the central nervous system (CNS is required in order to limit and control viral infection, but the presence of natural barrier structures, in particular the blood–brain barrier, strongly limits the perfusion of anti-HIV compounds into this anatomical site. Nanotechnology-based approaches may help providing solutions for antiretroviral drug delivery to the CNS by potentially prolonging systemic drug circulation, increasing the crossing and reducing the efflux of active compounds at the blood–brain barrier, and providing cell/tissue-targeting and intracellular drug delivery. After an initial overview on the basic features of HIV infection of the CNS and barriers to active compound delivery to this anatomical site, this review focuses on recent strategies based on antiretroviral drug-loaded solid nanoparticles and drug nanosuspensions for the potential management of HIV infection of the CNS. Keywords: HIV/AIDS, blood–brain barrier, protease inhibitors, efflux transporters, drug targeting

  17. Lengths of the maxillary central incisor, the nasal bone, and the anterior cranial base in different skeletal malocclusions

    DEFF Research Database (Denmark)

    Arntsen, Torill; Kjær, Inger; Sonnesen, Liselotte

    2009-01-01

    with neutral occlusion and normal craniofacial morphology (n=39). Two-way ANOVA tests were used to evaluate differences in lengths between groups and gender. Results. Statistically shorter maxillary central incisor length was found in the open bite group (p

  18. Coupling Between The North Indian Ocean And The Monsoons: A Model Based Study Of The Thermal Structure Cycling In The Central Arabian Sea

    Digital Repository Service at National Institute of Oceanography (India)

    Nayak, R.K.

    To examine the role of various intervening processes in controlling the upper ocean thermal structure in the central Arabian Sea, a 1-D mixed-layer model based on turbulent closure scheme is forced by atmospheric fluxes and advective heat fluxes...

  19. Public acceptance of disturbance-based forest management: a study of the Blue River Landscape Strategy in the Central Cascades Adaptive Management Area.

    Science.gov (United States)

    Bruce Shindler; Angela L. Mallon

    2009-01-01

    This report examines public perspectives on disturbance-based management conducted in the central Cascade Range in Oregon as part of the Blue River Landscape Strategy. A mail survey to local residents was used to describe the public’s understanding of this form of management, identify perceived associated risks and potential barriers to implementation, and the overall...

  20. Feasibility study of date (Phoenix dactylifera L.) fruit syrup-based natural jelly using central composite design.

    Science.gov (United States)

    Benali, Sonia; Benamara, Salem; Bigan, Muriel; Madani, Khodir

    2015-08-01

    A feasibility study of natural fruit jelly from three Algerian raw materials, namely date (Phoenix dactylifera l.) fruit syrup and suspension of orange albedo powder (OAP) in lemon juice (LJ) was performed by response surface methodology (RSM) based on central composite design (CCD). The textural properties of the final jelly were investigated through two dependent variables: hardness and stickiness. The cooking temperature (X1), corresponding to that of thermo stated oil bath, and cooking time (X 2), taken for heating the initial fruit mixture in the oil bath (from ambient temperature without fixing however, the final temperature), were found to be the most influent factors, compared to °Brix of date syrup (X3) and temperature (X4) of the cooling stage following the cooking process. Results have also shown that the second-degree polynomial models correctly fit experimental data (R(2), adjusted R(2) (R(2) adj) and cross-validation (Q(2)) ≈ 1). Considering textural properties of commercial jellies as a reference, it was found that the cooking temperature of 155 °C for 10 min gave a jelly with suitable textural properties. On the other hand, FT-IR spectra revealed that the structure of such jelly was partially close to that of pectin molecules. Finally, the color analysis in the CIELab system of the fruit mixture over the cooking process showed that both lightness (L(*)) and a*/b* ratio were not affected by the experienced temperature range (80-155 °C).

  1. Detection of planets in extremely weak central perturbation microlensing events via next-generation ground-based surveys

    International Nuclear Information System (INIS)

    Chung, Sun-Ju; Lee, Chung-Uk; Koo, Jae-Rim

    2014-01-01

    Even though the recently discovered high-magnification event MOA-2010-BLG-311 had complete coverage over its peak, confident planet detection did not happen due to extremely weak central perturbations (EWCPs, fractional deviations of ≲ 2%). For confident detection of planets in EWCP events, it is necessary to have both high cadence monitoring and high photometric accuracy better than those of current follow-up observation systems. The next-generation ground-based observation project, Korea Microlensing Telescope Network (KMTNet), satisfies these conditions. We estimate the probability of occurrence of EWCP events with fractional deviations of ≤2% in high-magnification events and the efficiency of detecting planets in the EWCP events using the KMTNet. From this study, we find that the EWCP events occur with a frequency of >50% in the case of ≲ 100 M E planets with separations of 0.2 AU ≲ d ≲ 20 AU. We find that for main-sequence and sub-giant source stars, ≳ 1 M E planets in EWCP events with deviations ≤2% can be detected with frequency >50% in a certain range that changes with the planet mass. However, it is difficult to detect planets in EWCP events of bright stars like giant stars because it is easy for KMTNet to be saturated around the peak of the events because of its constant exposure time. EWCP events are caused by close, intermediate, and wide planetary systems with low-mass planets and close and wide planetary systems with massive planets. Therefore, we expect that a much greater variety of planetary systems than those already detected, which are mostly intermediate planetary systems, regardless of the planet mass, will be significantly detected in the near future.

  2. A Review of a Successful Unsubsidized Market-Based Rural Solar Development Initiative in Laikipia District, Central Kenya

    Directory of Open Access Journals (Sweden)

    O. Wambuguh

    2013-10-01

    Full Text Available The development of renewable energy technologies (RETs in many areas far from grid-based electricity have primarily involved solar photovoltaics (SPVs which tap solar radiation to provide heat, light, hot water, electricity, and cooling for homes, businesses, and industry. A study on RETs took place in the Wiyumiririe Location of Laikipia District (north-central Kenya, a rich agricultural region. To explore this solar initiative in such a remote part of the country, a purposive randomized convenience sample of 246 households was selected and landowner interviews conducted, followed by field visits and observations. Although more than half of the households visited had SPV installations, solar energy was found to contribute only 18% of household estimated total energy needs; most residents still primarily relying on traditional energy sources. Several types of solar panels of different capacities and costs were utilized. Many landowners had at least one or two rooms using solar energy for household lighting, for appliance charging and to power radio and television. Almost all respondents appreciated that solar energy was clean renewable energy that greatly improved household living conditions; gave them some prestige; was easy to use and maintain; and was available year around. Although such significant benefits were associated with SPVs, only about 40% of residents interviewed were somehow satisfied with its development. Respondents expressed specific developmental initiatives that were closely associated with the availability of solar energy. Nevertheless, a number of challenges were raised associated with SPVs primarily investment capital and equipment costs and maintenance. As solutions to capital building will not solely rely on subsidies or individual farmer inputs, strategies must be found to mobilize the essential and tested tools for success including sustainable capital generation, building local institutions and capacities that

  3. Web Based Research Mapping and Analysis: ICT-AGRI's Meta Knowledge Base Centralizes ICT and Robotics Development in Agriculture and Related Environmental Issues

    Directory of Open Access Journals (Sweden)

    Koen C. Mertens

    2012-12-01

    Full Text Available Ample research is conducted on ICT, automation and robotics in agriculture and related environmental issues. ICT and Robotics innovations are rapidly emerging and have the ability to revolutionize future farming through their major impacts on productivity and profitability. Unfortunately human and financial resources and efforts are fragmented and limited. This led to the creation of the ICT-AGRI ERA-NET that provides a central structured framework. Its main objective is to strengthen and coordinate European research regarding ICT and robotics in agriculture. Besides the creation of the Meta Knowledge Base (MKB, a common European research agenda will be developed and common research calls are launched. The Meta Knowledge Base (http://db-ictagri.eu is attempting to map all relevant research and development within the selected research area. To accomplish the mapping, two types of information are collected: research profiles and research postings. To organize the postings, a three-dimensional task-technology oriented framework was designed. The results indicated that the three axes: task, technology and scope seemed insufficient to describe the whole research area. Therefore, an improved framework was developed. By extending the task-technology oriented framework with a process-control–information system, a useful framework was designed.

  4. Variability of floods, droughts and windstorms over the past 500 years in Central Europe based on documentary and instrumental data

    Science.gov (United States)

    Brazdil, Rudolf

    2016-04-01

    Hydrological and meteorological extremes (HMEs) in Central Europe during the past 500 years can be reconstructed based on instrumental and documentary data. Documentary data about weather and related phenomena represent the basic source of information for historical climatology and hydrology, dealing with reconstruction of past climate and HMEs, their perception and impacts on human society. The paper presents the basic distribution of documentary data on (i) direct descriptions of HMEs and their proxies on the one hand and on (ii) individual and institutional data sources on the other. Several groups of documentary evidence such as narrative written records (annals, chronicles, memoirs), visual daily weather records, official and personal correspondence, special prints, financial and economic records (with particular attention to taxation data), newspapers, pictorial documentation, chronograms, epigraphic data, early instrumental observations, early scientific papers and communications are demonstrated with respect to extraction of information about HMEs, which concerns usually of their occurrence, severity, seasonality, meteorological causes, perception and human impacts. The paper further presents the analysis of 500-year variability of floods, droughts and windstorms on the base of series, created by combination of documentary and instrumental data. Results, advantages and drawbacks of such approach are documented on the examples from the Czech Lands. The analysis of floods concentrates on the River Vltava (Prague) and the River Elbe (Děčín) which show the highest frequency of floods occurring in the 19th century (mainly of winter synoptic type) and in the second half of the 16th century (summer synoptic type). Reported are also the most disastrous floods (August 1501, March and August 1598, February 1655, June 1675, February 1784, March 1845, February 1862, September 1890, August 2002) and the European context of floods in the severe winter 1783/84. Drought

  5. Research on shock wave characteristics in the isolator of central strut rocket-based combined cycle engine under Ma5.5

    Science.gov (United States)

    Wei, Xianggeng; Xue, Rui; Qin, Fei; Hu, Chunbo; He, Guoqiang

    2017-11-01

    A numerical calculation of shock wave characteristics in the isolator of central strut rocket-based combined cycle (RBCC) engine fueled by kerosene was carried out in this paper. A 3D numerical model was established by the DES method. The kerosene chemical kinetic model used the 9-component and 12-step simplified mechanism model. Effects of fuel equivalence ratio, inflow total temperature and central strut rocket on-off on shock wave characteristics were studied under Ma5.5. Results demonstrated that with the increase of equivalence ratio, the leading shock wave moves toward upstream, accompanied with higher possibility of the inlet unstart. However, the leading shock wave moves toward downstream as the inflow total temperature rises. After the central strut rocket is closed, the leading shock wave moves toward downstream, which can reduce risks of the inlet unstart. State of the shear layer formed by the strut rocket jet flow and inflow can influence the shock train structure significantly.

  6. ScienceCentral: open access full-text archive of scientific journals based on Journal Article Tag Suite regardless of their languages.

    Science.gov (United States)

    Huh, Sun

    2013-01-01

    ScienceCentral, a free or open access, full-text archive of scientific journal literature at the Korean Federation of Science and Technology Societies, was under test in September 2013. Since it is a Journal Article Tag Suite-based full text database, extensible markup language files of all languages can be presented, according to Unicode Transformation Format 8-bit encoding. It is comparable to PubMed Central: however, there are two distinct differences. First, its scope comprises all science fields; second, it accepts all language journals. Launching ScienceCentral is the first step for free access or open access academic scientific journals of all languages to leap to the world, including scientific journals from Croatia.

  7. GIS-based landslide susceptibility mapping models applied to natural and urban planning in Trikala, Central Greece

    Directory of Open Access Journals (Sweden)

    Skilodimou, H. D.

    2009-06-01

    Full Text Available Landslide susceptibility mapping is a practical tool in natural and urban planning; it can be applied for determining land use zones, in construction design and planning of a variety of projects. In this study, two different GIS based landslide susceptibility maps were generated in the mountainous part of the Trikala Prefecture in Thessaly, Central Greece. This was accomplished by using different methods for correlating factors, which have an effect on landslide occurrences. The instability factors taken into account were: lithology, tectonic features, slope gradients, road network, drainage network, land use and rainfall. A frequency distribution of the half number of the landslide events of the study area in each class of the instability factors was performed in order to rate the classes. Two models have been used to combine the instability factors and assess the overall landslide susceptibility, namely: the Weight Factor Model (WeF, which is a statistical method, and the Multiple Factor Model (MuF that is a logical method. The produced maps were classified into four zones: Low, Moderate, High and Very High susceptible zones and validated using the other half number of the landslide events of the area. Evaluation of the results is optimized through a Landslide Models Indicator (La.M.I..Los mapas de susceptibilidad de deslizamientos representan una práctica herramienta en la planificación urbana y de espacios naturales. Así, puede aplicarse a la determinación de los usos de terrenos, en el diseño de construcción civil y para la planificación de gran variedad de actividades. En este estudio se generaron dos tipos diferentes de mapas de susceptibilidad basados en GIS para la parte montañosa de la prefectura de Trikala en Tesalia (Grecia Central. Estos se llevaron a cabo usando dos métodos de correlación de los factores que pueden tener un efecto en la generación de deslizamientos. Los factores de desestabilización tenidos en cuenta

  8. A GIS policy approach for assessing the effect of fertilizers on the quality of drinking and irrigation water and wellhead protection zones (Crete, Greece).

    Science.gov (United States)

    Kourgialas, Nektarios N; Karatzas, George P; Koubouris, Georgios C

    2017-03-15

    Fertilizers have undoubtedly contributed to the significant increase in yields worldwide and therefore to the considerable improvement of quality of life of man and animals. Today, attention is focussed on the risks imposed by agricultural fertilizers. These effects include the dissolution and transport of excess quantities of fertilizer major- and trace-elements to the groundwater that deteriorate the quality of drinking and irrigation water. In this study, a map for the Fertilizer Water Pollution Index (FWPI) was generated for assessing the impact of agricultural fertilizers on drinking and irrigation water quality. The proposed methodology was applied to one of the most intensively cultivated with tree crops area in Crete (Greece) where potential pollutant loads are derived exclusively from agricultural activities and groundwater is the main water source. In this region of 215 km 2 , groundwater sampling data from 235 wells were collected over a 15-year time period and analyzed for the presence of anionic (ΝΟ -3 , PO -3 4 ) and cationic (K +1 , Fe +2 , Mn +2 , Zn +2 , Cu +2 , B +3 ) fertilizer trace elements. These chemicals are the components of the primary fertilizers used in local tree crop production. Eight factors/maps were considered in order to estimate the spatial distribution of groundwater contamination for each fertilizer element. The eight factors combined were used to generate the Fertilizer Water Pollution Index (FWPI) map indicating the areas with drinking/irrigation water pollution due to the high groundwater contamination caused by excessive fertilizer use. Moreover, by taking into consideration the groundwater flow direction and seepage velocity, the pathway through which groundwater supply become polluted can be predicted. The groundwater quality results show that a small part of the study area, about 8 km 2 (3.72%), is polluted or moderately polluted by the excessive use of fertilizers. Considering that in this area drinking water sources

  9. Gaseous (DMS, MSA, SO2, H2SO4 and DMSO and particulate (sulfate and methanesulfonate sulfur species over the northeastern coast of Crete

    Directory of Open Access Journals (Sweden)

    H. Bardouki

    2003-01-01

    Full Text Available A detailed study of the levels, the temporal and diurnal variability of the main compounds involved in the biogenic sulfur cycle was carried out in Crete (Eastern Mediterranean during the Mediterranean Intensive Oxidant Study (MINOS field experiment in July-August 2001. Intensive measurements of gaseous dimethylsulfide (DMS, dimethylsulfoxide (DMSO, sulfur dioxide (SO2, sulfuric (H2SO4 and methanesulfonic acids (MSA and particulate sulfate (SO42- and methanesulfonate (MS- have been performed during the campaign. Dimethylsulfide (DMS levels ranged from 2.9 to 136 pmol·mol-1 (mean value of 21.7 pmol·mol-1 and showed a clear diurnal variation with daytime maximum. During nighttime DMS levels fall close or below the detection limit of 2 pmol·mol-1. Concurrent measurements of OH and NO3 radicals during the campaign indicate that NO3 levels can explain most of the observed diurnal variation of DMS. Dimethylsulfoxide (DMSO ranged between 0.02 and 10.1 pmol·mol-1 (mean value of 1.7 pmol·mol-1 and presents a diurnal variation similar to that of DMS. SO2 levels ranged from 220 to 2970 pmol·mol-1 (mean value of 1030 pmol·mol-1, while nss-SO42- and MS- ranged from 330 to 7100 pmol·mol-1, (mean value of 1440 pmol·mol-1 and 1.1 to 37.5 pmol·mol-1 (mean value of 11.5 pmol·mol-1 respectively. Of particular interest are the measurements of gaseous MSA and H2SO4. MSA ranged from below the detection limit (3x104 to 3.7x107 molecules cm-3, whereas H2SO4 ranged between 1x105 and 9.0x107 molecules cm-3. The measured H2SO4 maxima are among the highest reported in literature and can be attributed to high insolation, absence of precipitation and increased SO2 levels in the area. From the concurrent SO2, OH, and H2SO4 measurements a sticking coefficient of 0.52±0.28 was calculated for H2SO4. From the concurrent MSA, OH, and DMS measurements the yield of gaseous MSA from the OH-initiated oxidation of DMS was calculated to range between 0.1-0.4%. This low MSA

  10. Neuroarchitecture and neuroanatomy of the Drosophila central complex: A GAL4-based dissection of protocerebral bridge neurons and circuits.

    Science.gov (United States)

    Wolff, Tanya; Iyer, Nirmala A; Rubin, Gerald M

    2015-05-01

    Insects exhibit an elaborate repertoire of behaviors in response to environmental stimuli. The central complex plays a key role in combining various modalities of sensory information with an insect's internal state and past experience to select appropriate responses. Progress has been made in understanding the broad spectrum of outputs from the central complex neuropils and circuits involved in numerous behaviors. Many resident neurons have also been identified. However, the specific roles of these intricate structures and the functional connections between them remain largely obscure. Significant gains rely on obtaining a comprehensive catalog of the neurons and associated GAL4 lines that arborize within these brain regions, and on mapping neuronal pathways connecting these structures. To this end, small populations of neurons in the Drosophila melanogaster central complex were stochastically labeled using the multicolor flip-out technique and a catalog was created of the neurons, their morphologies, trajectories, relative arrangements, and corresponding GAL4 lines. This report focuses on one structure of the central complex, the protocerebral bridge, and identifies just 17 morphologically distinct cell types that arborize in this structure. This work also provides new insights into the anatomical structure of the four components of the central complex and its accessory neuropils. Most strikingly, we found that the protocerebral bridge contains 18 glomeruli, not 16, as previously believed. Revised wiring diagrams that take into account this updated architectural design are presented. This updated map of the Drosophila central complex will facilitate a deeper behavioral and physiological dissection of this sophisticated set of structures. © 2014 Wiley Periodicals, Inc.

  11. Architecture design of a generic centralized adjudication module integrated in a web-based clinical trial management system.

    Science.gov (United States)

    Zhao, Wenle; Pauls, Keith

    2016-04-01

    Centralized outcome adjudication has been used widely in multicenter clinical trials in order to prevent potential biases and to reduce variations in important safety and efficacy outcome assessments. Adjudication procedures could vary significantly among different studies. In practice, the coordination of outcome adjudication procedures in many multicenter clinical trials remains as a manual process with low efficiency and high risk of delay. Motivated by the demands from two large clinical trial networks, a generic outcome adjudication module has been developed by the network's data management center within a homegrown clinical trial management system. In this article, the system design strategy and database structure are presented. A generic database model was created to transfer different adjudication procedures into a unified set of sequential adjudication steps. Each adjudication step was defined by one activate condition, one lock condition, one to five categorical data items to capture adjudication results, and one free text field for general comments. Based on this model, a generic outcome adjudication user interface and a generic data processing program were developed within a homegrown clinical trial management system to provide automated coordination of outcome adjudication. By the end of 2014, this generic outcome adjudication module had been implemented in 10 multicenter trials. A total of 29 adjudication procedures were defined with the number of adjudication steps varying from 1 to 7. The implementation of a new adjudication procedure in this generic module took an experienced programmer 1 or 2 days. A total of 7336 outcome events had been adjudicated and 16,235 adjudication step activities had been recorded. In a multicenter trial, 1144 safety outcome event submissions went through a three-step adjudication procedure and reported a median of 3.95 days from safety event case report form submission to adjudication completion. In another trial

  12. Adapting to climate variability and change: experiences from cereal-based farming in the central rift and Kobo Valleys, Ethiopia.

    Science.gov (United States)

    Kassie, Belay Tseganeh; Hengsdijk, Huib; Rötter, Reimund; Kahiluoto, Helena; Asseng, Senthold; Van Ittersum, Martin

    2013-11-01

    Small-holder farmers in Ethiopia are facing several climate related hazards, in particular highly variable rainfall with severe droughts which can have devastating effects on their livelihoods. Projected changes in climate are expected to aggravate the existing challenges. This study examines farmer perceptions on current climate variability and long-term changes, current adaptive strategies, and potential barriers for successful further adaptation in two case study regions-the Central Rift Valley (CRV) and Kobo Valley. The study was based on a household questionnaire, interviews with key stakeholders, and focus group discussions. The result revealed that about 99 % of the respondents at the CRV and 96 % at the Kobo Valley perceived an increase in temperature and 94 % at CRV and 91 % at the Kobo Valley perceived a decrease in rainfall over the last 20-30 years. Inter-annual and intraseasonal rainfall variability also has increased according to the farmers. The observed climate data (1977-2009) also showed an increasing trend in temperature and high inter-annual and intra-seasonal rainfall variability. In contrast to farmers' perceptions of a decrease in rainfall totals, observed rainfall data showed no statistically significant decline. The interaction among various bio-physical and socio-economic factors, changes in rainfall intensity and reduced water available to crops due to increased hot spells, may have influenced the perception of farmers with respect to rainfall trends. In recent decades, farmers in both the CRV and Kobo have changed farming practices to adapt to perceived climate change and variability, for example, through crop and variety choice, adjustment of cropping calendar, and in situ moisture conservation. These relatively low-cost changes in farm practices were within the limited adaptation capacity of farmers, which may be insufficient to deal with the impacts of future climate change. Anticipated climate change is expected to impose new

  13. Adapting to Climate Variability and Change: Experiences from Cereal-Based Farming in the Central Rift and Kobo Valleys, Ethiopia

    Science.gov (United States)

    Kassie, Belay Tseganeh; Hengsdijk, Huib; Rötter, Reimund; Kahiluoto, Helena; Asseng, Senthold; Van Ittersum, Martin

    2013-11-01

    Small-holder farmers in Ethiopia are facing several climate related hazards, in particular highly variable rainfall with severe droughts which can have devastating effects on their livelihoods. Projected changes in climate are expected to aggravate the existing challenges. This study examines farmer perceptions on current climate variability and long-term changes, current adaptive strategies, and potential barriers for successful further adaptation in two case study regions—the Central Rift Valley (CRV) and Kobo Valley. The study was based on a household questionnaire, interviews with key stakeholders, and focus group discussions. The result revealed that about 99 % of the respondents at the CRV and 96 % at the Kobo Valley perceived an increase in temperature and 94 % at CRV and 91 % at the Kobo Valley perceived a decrease in rainfall over the last 20-30 years. Inter-annual and intraseasonal rainfall variability also has increased according to the farmers. The observed climate data (1977-2009) also showed an increasing trend in temperature and high inter-annual and intra-seasonal rainfall variability. In contrast to farmers’ perceptions of a decrease in rainfall totals, observed rainfall data showed no statistically significant decline. The interaction among various bio-physical and socio-economic factors, changes in rainfall intensity and reduced water available to crops due to increased hot spells, may have influenced the perception of farmers with respect to rainfall trends. In recent decades, farmers in both the CRV and Kobo have changed farming practices to adapt to perceived climate change and variability, for example, through crop and variety choice, adjustment of cropping calendar, and in situ moisture conservation. These relatively low-cost changes in farm practices were within the limited adaptation capacity of farmers, which may be insufficient to deal with the impacts of future climate change. Anticipated climate change is expected to impose new

  14. PROGNOSTIC FACTORS FOR PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMAS TREATED WITH HIGH-DOSE METHOTREXATE-BASED CHEMO-RADIOTHERAPY

    Science.gov (United States)

    Nagane, Motoo; Lee, Jeunghun; Shishido-Hara, Yukiko; Suzuki, Kaori; Shimizu, Saki; Umino, Michiru; Kobayashi, Keiichi; Shiokawa, Yoshiaki

    2014-01-01

    BACKGROUND: Chemotherapy with high-dose methotrexate (HD-MTX) followed by whole brain radiotherapy (WBRT) is a conventional approach to treat primary central nervous system lymphomas (PCNSL), but some tumors relapse early leading to unfavorable outcome. Several biomarkers have been identified as prognostic factors in PCNSL, however, the correlation of both clinical factors including those related to MTX metabolism and B-cell differentiation and oncogenic biomarkers with response to and outcome by therapy is yet unclear. METHODS: We investigated 32 immunocompetent patients (19 males, 13 females) with PCNSL (all diffuse large B-cell type) treated with HD-MTX based therapy with or without WBRT since 2000 in our institution. Paraffin-embedded formalin-fixed tumor tissue sections were stained immunohistochemically with antibodies against following factors: B-cell differentiation markers (CD10, Bcl-6, Mum-1, CD138); MTX metabolism-related (MRP family, LRP, DHFR); cell cycle-related (p27KIP1, MIB-1); drug resistance-related (MGMT, MLH1, MSH2, MSH6, PMS2); and oncogenes (Myc, Bcl-2). Correlation between positivity of these factors and clinical outcomes were evaluated using logrank test and cox regression analysis. RESULTS: Among these factors, complete response to HD-MTX was significantly associated with longer progression-free survival (PFS)(P = 0.0012), while Bcl-6 expression as well as histological subtype (non-germinal center B-cell, non-GCB) was closely correlated with shorter PFS. Age (>60) (P = 0.006) and MSH2 expression (P = 0.017) were found to be better predictor for overall survival (OS), but in multivariate analysis, they were no longer significant. Other factors involved in MTX metabolism, DNA repair enzymes, and oncogenes did not affect outcome. CONCLUSIONS: Non-GCB subtype and Bcl-6 expression may be associated with worse outcome in patients with PCNSL treated with HD-MTX, while MTX-metabolism related factors did not influence prognosis. Further

  15. Determination of central q and effective mass on textor based on discrete Alfven wave (DAW) spectrum measurements

    International Nuclear Information System (INIS)

    Descamps, P.; Wassenhove, G. van; Koch, R.; Messiaen, A.M.; Vandenplas, P.E.; Lister, J.B.; Marmillod, P.

    1990-01-01

    The use of the discrete Alfven wave spectrum to determine the current density profile and the effective mass density of the plasma in the TEXTOR tokamak is studied; the measurement, the validity of which is discussed, confirms independently the central q(r=0)<1 already obtained by polarimetry. (orig.)

  16. Dairy farmers’ business strategies in Central and Eastern Europe based on evidence from Lithuania, Poland and Slovenia

    NARCIS (Netherlands)

    Verhees, Frans; Malak-Rawlikowska, Agatsa; Stalgiene, Aldona; Kuipers, Abele; Klopčič, Marija

    2018-01-01

    To evaluate market-oriented strategic decision-making by farmers in Central and Eastern Europe (CEE) farm development paths of dairy farmers in Slovenia, Poland and Lithuania were analysed. The influence of internal strengths and weaknesses, external opportunities and threats, and farmer goals on

  17. Aetiologies of Central Nervous System Infection in Viet Nam: A Prospective Provincial Hospital-Based Descriptive Surveillance Study

    NARCIS (Netherlands)

    Ho Dang Trung, Nghia; Le Thi Phuong, Tu; Wolbers, Marcel; Nguyen van Minh, Hoang; Nguyen Thanh, Vinh; van, Minh Pham; Thieu, Nga Tran Vu; van, Tan Le; Song, Diep To; Thi, Phuong Le; Thi Phuong, Thao Nguyen; van, Cong Bui; Tang, Vu; Ngoc Anh, Tuan Hoang; Nguyen, Dong; Trung, Tien Phan; Thi Nam, Lien Nguyen; Kiem, Hao Tran; Thi Thanh, Tam Nguyen; Campbell, James; Caws, Maxine; Day, Jeremy; de Jong, Menno D.; van Vinh, Chau Nguyen; van Doorn, H. Rogier; Tinh, Hien Tran; Farrar, Jeremy; Schultsz, Constance; Loi, Tran Quoc; Son, Nguyen Truong; Bay, Phan Van Be; Tham, Nguyen Thi Hong; Phuong, Le Thi; Tri, Le Trung; Binh, Nguyen Thi Nguyet; Du, Doan Cong; Thao, Nguyen Thi Phuong; Tien, Truong Thi My; La, Tran Thi Phi; Cong, Bui Van; Diep, Pham Ngoc; Dong, Duong Phuoc; Lanh, Tran Thi Mong; Dom, Pham Van; Dung, Tran Quang; Tri, Phan Nhut; Ho, Tang Thi; Tai, Nguyen Anh; Luc, Quach Van; Phuoc, Dinh Xuan

    2012-01-01

    Background: Infectious diseases of the central nervous system (CNS) remain common and life-threatening, especially in developing countries. Knowledge of the aetiological agents responsible for these infections is essential to guide empiric therapy and develop a rational public health policy. To date

  18. Effect of direct seeding mulch-based systems on soil carbon storage and macrofauna in central Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Blanchart, E.; Bernoux, M.; Sarda, X.; Feller, C. [Institut de Recherche pour le Developpement, Montpellier (France); Siqueira Neto, M.; Cerri, C.C.; Piccolo, M. [CENA-USP, Piracicaba (Brazil). Lab. Biogeoquimica Ambiental; Douzet, J.M. [CIRAD, Antsirabe (Madagascar); Scopel, E. [CIRAD-CA, Planaltina (Brazil)

    2007-07-01

    Soils represent a large carbon pool, approximately 1500 Gt, equivalent to almost three times the quantity stored in terrestrial biomass and twice the amount stored in the atmosphere. The management and maintenance of soil carbon is therefore an integral part of the global carbon cycle. Land use change, inappropriate agricultural practices and climate change can all lead to a net release of C from soils to the atmosphere, exacerbating the problems of greenhouse gas release. Any modification of land-use or land management can induce variations in soil carbon stocks, even in agricultural systems that are perceived to be in a steady state. These modifications also alter soil macrofauna that is known to affect soil carbon dynamics. Direct seeding Mulch-based Cropping (DMC) systems with two crops per year without soil tillage have widely been adopted over the last 10 to 15 years in the Cerrado (central region) of Brazil. They are replacing the traditional soybean monocropping with fallow under conventional tillage (CT). Th e objective of this study was to examine how DMC practices affect soil organic carbon (SOC) dynamics and macrofauna (Rio Verde, Goias State). The approach was to determine soil C stocks and macrofauna in five fi elds under DMC aged 1, 5, 7, 11 and 13 years. In order to compare DMC systems with the native system of the region and previous land-use, a situation under native Cerrado (tree-savanna like vegetation) and a field conducted traditionally (CT) were also studied. Soil C stocks were calculated for the 0-10 and 0-40 cm soil depth and also for the fi rst 400 kg m{sup -2} of soil to compare the same amount of soil and to suppress the potential artefact of soil compaction when sample is based on fix layer depth. Soil macrofauna was hand-sorted from soil monoliths (30 cm depth, TSBF method). In our study, the annual rate of carbon storage was equal to ca. 1.6 MgC ha{sup -1}, which is in the range of values measured for DMC in different areas of Brazil

  19. Alpha current flow betweenness centrality

    NARCIS (Netherlands)

    Avrachenkov, K.; Litvak, Nelli; Medyanikov, V.; Sokol, M.

    2013-01-01

    A class of centrality measures called betweenness centralities reflects degree of participation of edges or nodes in communication between different parts of the network. The original shortest-path betweenness centrality is based on counting shortest paths which go through a node or an edge. One of

  20. Application of fractal modeling and PCA method for hydrothermal alteration mapping in the Saveh area (Central Iran) based on ASTER multispectral data

    OpenAIRE

    Mirko Ahmadfaraj; Mirsaleh Mirmohammadi; Peyman Afzal

    2016-01-01

    The aim of this study is determination and separation of alteration zones using Concentration-Area (C-A) fractal model based on remote sensing data which has been extracted from Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) images. The studied area is on the SW part of Saveh, 1:250,000 geological map, which is located in Urumieh-Dokhtar magmatic belt, Central Iran. The pixel values were computed by Principal Component Analysis (PCA) method used to determine phyllic, a...

  1. Isolation and Characterization of Orientia tsutsugamushi from Rodents Captured following a Scrub Typhus Outbreak at a Military Training Base, Bothong District, Chonburi Province, Central Thailand

    OpenAIRE

    Rodkvamtook, Wuttikon; Ruang-areerate, Toon; Gaywee, Jariyanart; Richards, Allen L.; Jeamwattanalert, Pimmada; Bodhidatta, Dharadhida; Sangjun, Noppadon; Prasartvit, Anchana; Jatisatienr, Araya; Jatisatienr, Chaiwat

    2011-01-01

    Orientia tsutsugamushi, an obligate intracellular Gram-negative bacterium, is the causative agent of scrub typhus, a vector-borne disease transmitted by infected chiggers (trombiculid mite larvae). In 2002, an outbreak of scrub typhus occurred among Royal Thai Army troops during the annual field training at a military base in Bothong district, Chonburi province, central Thailand. This report describes the outbreak investigation including its transmission cycle. Results showed that 33.9% of 17...

  2. Towards Food Security and Livelihoods of Low-income Women in central Uganda: Policy Implications based on action research

    DEFF Research Database (Denmark)

    Nambuanyi, Lekunze Ransom; Midtvåge, Runa; Hiranandani, Vanmala Sunder

    2015-01-01

    Uganda is burdened with rising poverty, malnutrition and food insecurity. While most Ugandans depend on agriculture for their livelihoods, it is important to recognize that access to and control over resources by women and climate factors are central to the question of food security in Uganda....... However, a review of the literature demonstrates that policy options have poorly understood these interlinkages or tended to undermine them, especially the extent that these policies and programs put the necessary attention on the role of women farmers in food security. This paper presents part of a work...... in progress of a research project that seeks to investigate the interrelated effects of agricultural practices, access to and control over resources, as well as climate change on women’s food security in the urban and peri-urban areas of central Uganda. The paper not only considers how to turn...

  3. Correlation of proterozoic sediments of Western and Central Africa and South America based upon radiochronological and paleontological data

    International Nuclear Information System (INIS)

    Bonhomme, M.G.

    1982-01-01

    Nearly 70 new Rb-Sr isochron ages and many K-Ar conventional ages have been determined between 1975 and 1980 on Proterozoic sedimentary or metasedimentary sequences in western and Central Africa and South America. Some stratigraphic results have been established: (1) five formations have been dated of the Lower Proterozoic; (2) a long sedimentation gap occurs, mainly in western Africa and in some regions of Central Africa and South America between nearly 1600 and 1100 Ma; (3) the upper Riphean assemblages of stromatolites have been dated and compared to those of the Eurasian craton; (4) two main glacial events have been dated, the first one placed at ca. 950 Ma, the second during the Vendian, at ca. 650-620 Ma; (5) it can be stated that, when applied to Precambrian sequences, all stratigraphic methods must be used together. (Auth.)

  4. DESIGN APPLICATIONS BASED ON WEB MOBILE AT GAYA BARU SENIOR HIGH SCHOOL, CENTRAL LAMPUNG REGENCY AS PROMOTIONAL MEDIA

    Directory of Open Access Journals (Sweden)

    Ahmad Yudi

    2017-05-01

    Full Text Available Gaya Baru Senior High School is one of the educational institutions in Lampung which is a less favorite institution in the area is precisely located in the district of Seputih Surabaya Central Lampung Regency. Gaya Baru Senior High School has already had a website but not many known. This Senior High School is also no information system through mobile web to promote the institution. Nevertheless, in its development, students or community want to find information about the school can be directly through the mobile web application. So in its development requires fast service. From research that conducted in Gaya Baru High School, existence of new mobile web application system will facilitate student or society of that area, especially in subdistrict Seputih Surabaya district Central Lampung, and present information about the info about situation in high school of new style it can be accessed directly through the mobile web media.

  5. Environmental Assessment: Demolition of McGuire Central Heat Plant at Joint Base McGuire-Dix-Lakehurst, New Jersey

    Science.gov (United States)

    2012-06-01

    insulation, boiler, holding tank and duct coverings, floor tiles , window caulking/glazing, and corrugated building siding. The asbestos insulation and...facility, with the Bulk Fuel Storage area and the golf course located between them. BOMARC is located several miles from the proposed solar sites...Architectural Resources The Central Heat Plant was constructed in 1956. It is a flat- roofed building originally rectangular in form, and is now L-shaped. The

  6. TrajGraph: A Graph-Based Visual Analytics Approach to Studying Urban Network Centralities Using Taxi Trajectory Data.

    Science.gov (United States)

    Huang, Xiaoke; Zhao, Ye; Yang, Jing; Zhang, Chong; Ma, Chao; Ye, Xinyue

    2016-01-01

    We propose TrajGraph, a new visual analytics method, for studying urban mobility patterns by integrating graph modeling and visual analysis with taxi trajectory data. A special graph is created to store and manifest real traffic information recorded by taxi trajectories over city streets. It conveys urban transportation dynamics which can be discovered by applying graph analysis algorithms. To support interactive, multiscale visual analytics, a graph partitioning algorithm is applied to create region-level graphs which have smaller size than the original street-level graph. Graph centralities, including Pagerank and betweenness, are computed to characterize the time-varying importance of different urban regions. The centralities are visualized by three coordinated views including a node-link graph view, a map view and a temporal information view. Users can interactively examine the importance of streets to discover and assess city traffic patterns. We have implemented a fully working prototype of this approach and evaluated it using massive taxi trajectories of Shenzhen, China. TrajGraph's capability in revealing the importance of city streets was evaluated by comparing the calculated centralities with the subjective evaluations from a group of drivers in Shenzhen. Feedback from a domain expert was collected. The effectiveness of the visual interface was evaluated through a formal user study. We also present several examples and a case study to demonstrate the usefulness of TrajGraph in urban transportation analysis.

  7. Analysis of bacterial core communities in the central Baltic by comparative RNA-DNA-based fingerprinting provides links to structure-function relationships.

    Science.gov (United States)

    Brettar, Ingrid; Christen, Richard; Höfle, Manfred G

    2012-01-01

    Understanding structure-function links of microbial communities is a central theme of microbial ecology since its beginning. To this end, we studied the spatial variability of the bacterioplankton community structure and composition across the central Baltic Sea at four stations, which were up to 450 km apart and at a depth profile representative for the central part (Gotland Deep, 235 m). Bacterial community structure was followed by 16S ribosomal RNA (rRNA)- and 16S rRNA gene-based fingerprints using single-strand conformation polymorphism (SSCP) electrophoresis. Species composition was determined by sequence analysis of SSCP bands. High similarities of the bacterioplankton communities across several hundred kilometers were observed in the surface water using RNA- and DNA-based fingerprints. In these surface communities, the RNA- and DNA-based fingerprints resulted in very different pattern, presumably indicating large difference between the active members of the community as represented by RNA-based fingerprints and the present members represented by the DNA-based fingerprints. This large discrepancy changed gradually over depth, resulting in highly similar RNA- and DNA-based fingerprints in the anoxic part of the water column below 130 m depth. A conceivable mechanism explaining this high similarity could be the reduced oxidative stress in the anoxic zone. The stable communities on the surface and in the anoxic zone indicate the strong influence of the hydrography on the bacterioplankton community structure. Comparative analysis of RNA- and DNA-based community structure provided criteria for the identification of the core community, its key members and their links to biogeochemical functions.

  8. ecological geological maps: GIS-based evaluation of the Geo-Ecological Quality Index (GEQUI) in Sicily (Central Mediterranean)

    Science.gov (United States)

    Nigro, Fabrizio; Arisco, Giuseppe; Perricone, Marcella; Renda, Pietro; Favara, Rocco

    2010-05-01

    The condition of landscapes and the ecological communities within them is strongly related to levels of human activity. As a consequence, determining status and trends in the pattern of human-dominated landscapes can be useful for understanding the overall conditions of geo-ecological resources. Ecological geological maps are recent tools providing useful informations about a-biotic and biotic features worldwide. These maps represents a new generation of geological maps and depict the lithospheric components conditions on surface, where ecological dynamics (functions and properties) and human activities develop. Thus, these maps are too a fundamental political tool to plan the human activities management in relationship to the territorial/environmental patterns of a date region. Different types of ecological geological maps can be develop regarding the: conditions (situations), zoning, prognosis and recommendations. The ecological geological conditions maps reflects the complex of parameters or individual characteristics of lithosphere, which characterized the opportunity of the influence of lithosphere components on the biota (man, fauna, flora, and ecosystem). The ecological geological zoning maps are foundamental basis for prognosis estimation and nature defenses measures. Estimation from the position of comfort and safety of human life and function of ecosystem is given on these maps. The ecological geological prognosis maps reflect the spatial-temporary prognoses of ecological geological conditions changing during the natural dynamic of natural surrounding and the main-during the economic mastering of territory and natural technical systems. Finally, the ecological geological recommendation maps are based on the ecological geological and social-economical informations, aiming the regulation of territory by the regulation of economic activities and the defense of bio- and socio-sphere extents. Each of these maps may also be computed or in analytic or in

  9. Effect of an innovative community based health program on maternal health service utilization in north and south central Ethiopia: a community based cross sectional study.

    Science.gov (United States)

    Afework, Mesganaw Fantahun; Admassu, Kesteberhan; Mekonnen, Alemayehu; Hagos, Seifu; Asegid, Meselech; Ahmed, Saifuddin

    2014-04-04

    Among Millennium Development Goals, achieving the fifth goal (MDG-5) of reducing maternal mortality poses the greatest challenge in Sub-Saharan Africa. Ethiopia has one of the highest maternal mortality ratios in the world with unacceptably low maternal health service utilization. The Government of Ethiopia introduced an innovative community-based intervention as a national strategy under the Health Sector Development Program. This new approach, known as the Health Extension Program, aims to improve access to and equity in essential health services through community based Health Extension Workers. The objective of the study is to assess the role of Health Extension Workers in improving women's utilization of antenatal care, delivery at health facility and postnatal care services. A cross sectional household survey was conducted in early 2012 in two districts of northern and south central parts of Ethiopia. Data were collected from 4949 women who had delivered in the two years preceding the survey. Logistic regression analysis was performed to determine the association between visit by Health Extension Workers during pregnancy and use of maternal health services, controlling for the effect of other confounding factors. The non-adjusted analysis showed that antenatal care attendance at least four times during pregnancy was significantly associated with visit by Health Extension Workers [Odds Ratio 3.46(95% CI 3.07,3.91)], whereas health facility delivery (skilled attendance at birth) was not significantly associated with visit by Health Extension Workers during pregnancy [Odds Ratio 0.87(95% CI 0.25,2.96)]. When adjusted for other factors the association of HEWs visit during pregnancy was weaker for antenatal care attendance [Adjusted Odds Ratio: 1.35(95% CI: 1.05, 1.72)] but positively and significantly associated with health facility delivery [Adjusted Odds Ratio 1.96(1.25,3.06)]. In general HEWs visit during pregnancy improved utilization of maternal health

  10. Central Chile

    Science.gov (United States)

    2002-01-01

    The beginning of spring in central Chile looked like this to SeaWiFS. The snow-covered Andes mark the country's eastern border, and phytoplankton blooms and river sediment plumes fill the waters off its west coast. A large eddy due west of Concepcion is highlighted by the phytoplankton it contains.

  11. Afrique Centrale

    African Journals Online (AJOL)

    PR BOKO

    (Afrique Centrale) : peuplement de protozoaires ciliés et macro invertébrés ... Le lac d'Obili est un écosystème aquatique situé en plein cœur de Yaoundé en ...... électrique des eaux est assez stable, autour de 200 ; ce qui suppose que la ...

  12. Determination of Natural and Anthropogenic Factors on Pollution of Heavy Metals in the Central Zanjan (Based on Multivariate Analysis

    Directory of Open Access Journals (Sweden)

    A. Afshari

    2017-01-01

    Full Text Available Introduction: Soil forms a thin layer over the surface of the earth that performs many essential life processes . Soil has always been important to humans and their health, providing a resource that can be used for shelter and food production. Higher heavy metals concentration within soils has beenshown to be toxic for human bodies, since they might be broken out easily via dust or direct contact through trophic levels. In addition long term heavy metals recalcitrance in soil results in low potential of soil productivity . Heavy metals interact complicatedly in soil. The present study was conducted in large scale by analyzing elements Mn, Co, Ni, Zn, Pb, Cd and Cu in soils in central lands of Zanjan province. The main objectives of present research were to investigate heavy metals diffusion and total contamination status in soil and determination of their possible origin using multivariate analysis. Materials and Methods: This research was conducted in central lands located in Zanjan province (northwest of Iran. In terms of the main land uses, study area may involve farmlands, rangelands, urbanized and industrial lands. Study sites are totally covered 2000 km2 in coordinates of 36.20 to 36.41 N latitude and 48.19 to 48.53 E longitude. Sampling was conducted based on gridding method in randomized manner in August 2011. Urban lands affected by much anthropogenic activities and farm and rangelands together were placed in grids of 1.5×x 1.5 and 3×3 km2 respectively. Totally number of 241 soil samples (0-10 cm depth was taken. Soil specimen's digestions were conducted using nitric acid 5 normal. Total elements concentration of Pb, Zn, Ni, Mn, Cu, Cr, Fe and Co were measured using Atomic adsorption device Perkin-Elmer: AA 200 and Cd concentration was determined by Atomic adsorption device equipped with graphic furnace model Rayleigh: WF-1E. Mean separation analysis of parameters (Pearson and spearman was conducted using Duncan test in probability

  13. Contemporary changes of water resources, water and land use in Central Asia based on observations and modeling.

    Science.gov (United States)

    Shiklomanov, A. I.; Prousevitch, A.; Sokolik, I. N.; Lammers, R. B.

    2015-12-01

    Water is a key agent in Central Asia ultimately determining human well-being, food security, and economic development. There are complex interplays among the natural and anthropogenic drivers effecting the regional hydrological processes and water availability. Analysis of the data combined from regional censuses and remote sensing shows a decline in areas of arable and irrigated lands and a significant decrease in availability of arable and irrigated lands per capita across all Central Asian countries since the middle of 1990thas the result of post-Soviet transformation processes. This change could lead to considerable deterioration in food security and human system sustainability. The change of political situation in the region has also resulted in the escalated problems of water demand between countries in international river basins. We applied the University of New Hampshire - Water Balance Model - Transport from Anthropogenic and Natural Systems (WBM-TrANS) to understand the consequences of changes in climate, water and land use on regional hydrological processes and water availability. The model accounts for sub-pixel land cover types, glacier and snow-pack accumulation/melt across sub-pixel elevation bands, anthropogenic water use (e.g. domestic and industrial consumption, and irrigation for most of existing crop types), hydro-infrastructure for inter-basin water transfer and reservoir/dam regulations. A suite of historical climate re-analysis and temporal extrapolation of MIRCA-2000 crop structure datasets has been used in WBM-TrANS for this project. A preliminary analysis of the model simulations over the last 30 years has shown significant spatial and temporal changes in hydrology and water availability for crops and human across the region due to climatic and anthropogenic causes. We found that regional water availability is mostly impacted by changes in extents and efficiency of crop filed irrigation, especially in highly arid areas of Central Asia

  14. A new PCR-based approach indicates the range of Clonorchis sinensis now extends to Central Thailand.

    Directory of Open Access Journals (Sweden)

    Rebecca J Traub

    Full Text Available Differentiation of the fish-borne trematodes belonging to the Opisthorchiidae, Heterophyidae and Lecithodendriidae is important from a clinical and epidemiological perspective, yet it is impossible to do using conventional coprological techniques, as the eggs are morphologically similar. Epidemiological investigation therefore currently relies on morphological examination of adult worms following expulsion chemotherapy. A PCR test capable of amplifying a segment of the internal transcribed spacer region of ribosomal DNA for the opisthorchiid and heterophyid flukes eggs taken directly from faeces was developed and evaluated in a rural community in central Thailand. The lowest quantity of DNA that could be amplified from individual adults of Opisthorchis viverrini, Clonorchis sinensis and Haplorchis taichui was estimated at 0.6 pg, 0.8 pg and 3 pg, respectively. The PCR was capable of detecting mixed infection with the aforementioned species of flukes under experimental conditions. A total of 11.6% of individuals in rural communities in Sanamchaikaet district, central Thailand, were positive for 'Opisthorchis-like' eggs in their faeces using conventional parasitological detection techniques. In comparison to microscopy, the PCR yielded a sensitivity and specificity of 71.0% and 76.7%, respectively. Analysis of the microscopy-positive PCR products revealed 64% and 23% of individuals to be infected with O. viverrini and C. sinensis, respectively. The remaining 13% (three individuals were identified as eggs of Didymozoidae, presumably being passed mechanically in the faeces following the ingestion of infected fishes. An immediate finding of this study is the identification and first report of a C. sinensis-endemic community in central Thailand. This extends the known range of this liver fluke in Southeast Asia. The PCR developed herein provides an important tool for the specific identification of liver and intestinal fluke species for future

  15. Estimation of recurrence interval of large earthquakes on the central Longmen Shan fault zone based on seismic moment accumulation/release model.

    Science.gov (United States)

    Ren, Junjie; Zhang, Shimin

    2013-01-01

    Recurrence interval of large earthquake on an active fault zone is an important parameter in assessing seismic hazard. The 2008 Wenchuan earthquake (Mw 7.9) occurred on the central Longmen Shan fault zone and ruptured the Yingxiu-Beichuan fault (YBF) and the Guanxian-Jiangyou fault (GJF). However, there is a considerable discrepancy among recurrence intervals of large earthquake in preseismic and postseismic estimates based on slip rate and paleoseismologic results. Post-seismic trenches showed that the central Longmen Shan fault zone probably undertakes an event similar to the 2008 quake, suggesting a characteristic earthquake model. In this paper, we use the published seismogenic model of the 2008 earthquake based on Global Positioning System (GPS) and Interferometric Synthetic Aperture Radar (InSAR) data and construct a characteristic seismic moment accumulation/release model to estimate recurrence interval of large earthquakes on the central Longmen Shan fault zone. Our results show that the seismogenic zone accommodates a moment rate of (2.7 ± 0.3) × 10¹⁷ N m/yr, and a recurrence interval of 3900 ± 400 yrs is necessary for accumulation of strain energy equivalent to the 2008 earthquake. This study provides a preferred interval estimation of large earthquakes for seismic hazard analysis in the Longmen Shan region.

  16. Estimation of Recurrence Interval of Large Earthquakes on the Central Longmen Shan Fault Zone Based on Seismic Moment Accumulation/Release Model

    Directory of Open Access Journals (Sweden)

    Junjie Ren

    2013-01-01

    Full Text Available Recurrence interval of large earthquake on an active fault zone is an important parameter in assessing seismic hazard. The 2008 Wenchuan earthquake (Mw 7.9 occurred on the central Longmen Shan fault zone and ruptured the Yingxiu-Beichuan fault (YBF and the Guanxian-Jiangyou fault (GJF. However, there is a considerable discrepancy among recurrence intervals of large earthquake in preseismic and postseismic estimates based on slip rate and paleoseismologic results. Post-seismic trenches showed that the central Longmen Shan fault zone probably undertakes an event similar to the 2008 quake, suggesting a characteristic earthquake model. In this paper, we use the published seismogenic model of the 2008 earthquake based on Global Positioning System (GPS and Interferometric Synthetic Aperture Radar (InSAR data and construct a characteristic seismic moment accumulation/release model to estimate recurrence interval of large earthquakes on the central Longmen Shan fault zone. Our results show that the seismogenic zone accommodates a moment rate of (2.7 ± 0.3 × 1017 N m/yr, and a recurrence interval of 3900 ± 400 yrs is necessary for accumulation of strain energy equivalent to the 2008 earthquake. This study provides a preferred interval estimation of large earthquakes for seismic hazard analysis in the Longmen Shan region.

  17. Comparison of Estrogen Receptor Assay Results from Pathology Reports with Results from Central Laboratory Testing: Implications for Population-Based Studies of Breast Cancer

    Science.gov (United States)

    Collins, LC; Marotti, J; Baer, HJ; Deitz, AC; Colditz, GA; Tamimi, RM

    2014-01-01

    Population-based studies of women with breast cancer commonly utilize information culled from pathology reports rather than central pathology review. The reliability of this information, particularly with regard to tumor biomarker results, is of concern. To address this, we evaluated the concordance between estrogen receptor (ER) results as determined from the original pathology reports and ER results obtained on the same specimens following testing in a single laboratory. Tissue microarrays (TMAs) were constructed from paraffin blocks of 3,167 breast cancers that developed in women enrolled in the Nurses’ Health Study. ER immunostains were performed on all TMA sections in single run. Results of ER immunostains performed on the TMA sections were compared with ER assay results abstracted from pathology reports. Among 1,851 cases of invasive breast cancer in which both ER results from pathology reports and central ER test results were available, the reported ER status and the ER status as determined from immunostains on TMAs were in agreement in 1,651 cases (87.3 %; kappa value 0.64, ppathology reports is a reasonable, albeit imperfect, alternative to central laboratory ER testing for large, population-based studies of patients with breast cancer. PMID:18230800

  18. Optimization of Personnel Assignment Problem Based on Traveling Time by Using Hungarian Methods: Case Study on the Central Post Office Bandung

    Science.gov (United States)

    Supian, Sudradjat; Wahyuni, Sri; Nahar, Julita; Subiyanto

    2018-01-01

    In this paper, traveling time workers from the central post office Bandung in delivering the package to the destination location was optimized by using Hungarian method. Sensitivity analysis against data changes that may occur was also conducted. The sampled data in this study are 10 workers who will be assigned to deliver mail package to 10 post office delivery centers in Bandung that is Cikutra, Padalarang, Ujung Berung, Dayeuh Kolot, Asia- Africa, Soreang, Situ Saeur, Cimahi, Cipedes and Cikeruh. The result of this research is optimal traveling time from 10 workers to 10 destination locations. The optimal traveling time required by the workers is 387 minutes to reach the destination. Based on this result, manager of the central post office Bandung can make optimal decisions to assign tasks to their workers.

  19. Secular trends in fitness, moderate-to-vigorous physical activity, and TV-viewing among first grade school children of Crete, Greece between 1992/93 and 2006/07.

    Science.gov (United States)

    Smpokos, Emmanouil A; Linardakis, Manolis; Papadaki, Angeliki; Lionis, Christos; Kafatos, Anthony

    2012-03-01

    To assess secular changes in physical fitness (PF), moderate-to-vigorous-physical activity (MVPA) and TV-viewing in 1st-grade children from Crete, Greece. Cross-sectional cohorts examined in academic years 1992/93 and 2006/07. Two representative samples of children, aged 5.9-7.8 years, were studied during 1992/93 (N=606) and 2006/07 (N=361). PF (sit-and-reach, standing-broad-jump, sit-ups and 20 m-shuttle-run-test) was assessed by the European-PF test battery and MVPA by a physical activity (PA) questionnaire. Data on the frequency of TV-viewing was also collected. Between 1992/93 and 2006/07, there was a significant increase in all fitness tests in both genders (Pgenders in 2006/07, compared to 1992/93 (Pactive boys and active girls spent more time in MVPA than active boys and girls in 1992/93 (Pactivities in 2006/07, than 1992/93 (Pphysical and cardiorespiratory fitness in both genders and MVPA in boys was observed in children from Crete between 1992/93 and 2006/07. The increase in weekday TV-viewing, despite being parallel to an increase in leisure-time MVPA, could have an unfavorable effect on health and should be tackled in future interventions in this population. Dietary, anthropometric and biochemical indices should also be investigated to assess their impact on the secular changes in physical fitness and activity observed in this sample of children. Copyright © 2011 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  20. Load Distribution of Semi-Central Evaporative Cooling Air-Conditioning System Based on the TRNSYS Platform

    Directory of Open Access Journals (Sweden)

    Ji Li

    2018-05-01

    Full Text Available Evaporative cooling is a green, energy-efficient cooling technology adopted in hot and dry regions, which has wider application in the field of air-conditioning systems. Outdoor meteorological parameters have a great influence on the operation mode and control strategy of evaporative cooling air-conditioning systems, and the system load distribution and system configuration will be affected. This paper aims at investigating the load distribution of semi-central evaporative cooling air-conditioning systems under the condition of hourly outdoor meteorological parameters. Firstly, this paper introduced the design partition, operation mode, controlling strategy and load distribution method on semi-central evaporative cooling air-conditioning system. Then, taking an office building in Lanzhou (China as an example, the evaporative cooling air-conditioning system was divided into five regions and the load distribution was simulated by TRNSYS (The Transient Energy System Simulation Tool under the condition of hourly outdoor meteorological parameters. Finally, the results have shown that the evaporative cooling air-conditioning system can provide 25.46% of the building loads, which was of great significance to reduce the energy consumption of air-conditioning system.

  1. Spatial distribution level of land erosion disposition based on the analysis of slope on Central Lematang sub basin

    Science.gov (United States)

    Putranto, Dinar Dwi Anugerah; Sarino, Yuono, Agus Lestari

    2017-11-01

    Soil erosion is a natural process that is influenced by the magnitude of rainfall intensity, land cover, slope, soil type and soil processing system. However, it is often accelerated by human activities, such as improper cultivation of agricultural land, clearing of forest land for mining activities, and changes in topographic area due to use for other purposes such as pile materials, mined pits and so on. The Central Lematang sub-basin is part of the Lematang sub basin, at the Musi River Region Unit, South Sumatra Province, in Indonesia, which has a topographic shape with varying types of slope and altitude. The critical condition of Central Lematang sub basin has been at an alarming rate, as more than 47.5% of topographic and land use changes are dominated by coal mining activities and forest encroachment by communities. The method used in predicting erosion is by USPED (Unit Stream Power Erosion and Disposition). This is because the USPED [1] method can predict not only sediment transport but also the value of peeling (detachment) and sediment deposition. From slope analysis result, it is found that the highest erosion potential value is found on slope (8-15%) and the sediment is carried on a steep slope (15-25%). Meanwhile, the high sediment deposition area is found in the waters of 5.226 tons / ha / year, the steeper area of 2.12 tons / ha / year.

  2. Unusual polymorphism in new bent-shaped liquid crystals based on biphenyl as a central molecular core

    Directory of Open Access Journals (Sweden)

    Anna Kovářová

    2014-04-01

    Full Text Available Bent-shaped mesogens possessing a biphenyl as a central core have been synthesized and the role of the terminal chain and the orientation of the ester as a linkage group have been investigated. For the studied molecular core we have established that both parameters play an important role for the mesomorphic properties. The polyfluoroalkyl terminal chain supports the formation of mesophases, and the introduction of a chiral lactate terminal chain destabilizes mesophases for the first type of mutual orientation of ester groups, attached to the central core. On the contrary, for the opposite orientation of esters, the terminal chain has no effect on the mesomorphic properties, and columnar phases have been found for all compounds. A unique phase sequence has been found for the mesogen with the fluorinated chain. A generalized tilted smectics, SmCG, have been observed in a temperature interval between two different lamellar SmCP phases and characterized by X-ray and dielectric measurements. The dielectric spectroscopy data are unique and presented for the first time in the SmCG phase providing new information about the molecular dynamics.

  3. Europa central

    Directory of Open Access Journals (Sweden)

    Karel BARTOSEK

    2010-02-01

    Full Text Available La investigación francesa continúa interesándose por Europa Central. Desde luego, hay límites a este interés en el ambiente general de mi nueva patria: en la ignorancia, producto del largo desinterés de Francia por este espacio después de la Segunda Guerra Mundial, y en el comportamiento y la reflexión de la clase política y de los medios de comunicación (una anécdota para ilustrar este ambiente: durante la preparación de nuestro coloquio «Refugiados e inmigrantes de Europa Central en el movimiento antifascista y la Resistencia en Francia, 1933-1945», celebrado en París en octubre de 1986, el problema de la definición fue planteado concreta y «prácticamente». ¡Y hubo entonces un historiador eminente, para quién Alemania no formaría parte de Europa Central!.

  4. The performance of the ZEUS central tracking detector z-by-timing electronics in a transputer based data acquisition system

    International Nuclear Information System (INIS)

    Foster, B.; Heath, G.P.; Llewellyn, T.J.; Gingrich, D.M.; Harnew, N.; Hallam-Baker, P.M.; Khatri, T.; McArthur, I.C.; Morawitz, P.; Nash, J.; Shield, P.D.; Topp-Jorgensen, S.; Wilson, F.F.; Allen, D.B.; Carter, R.C.; Jeffs, M.D.; Morrissey, M.C.; Quinton, S.P.H.; Lane, J.B.; Postranecky, M.

    1993-01-01

    The Central Tracking Detector of the ZEUS experiment employs a time difference technique to measure the z coordinate of each hit. The method provides fast, three-dimensional space point measurements which are used as input to all levels of the ZEUS trigger. Such a tracking trigger is essential in order to discriminate against events with vertices lying outside the nominal electron-proton interaction region. Since the beam crossing interval of the HERA collider is 96 ns, all data must be pipelined through the front-end readout electronics. Subsequent data aquisition employs a novel technique which utilizes a network of approximately 120 INMOS transputers to process the data in parallel. The z-by-timing method and its data aquisition have been employed successfully in recording and reconstructing tracks from electron-proton interactions in ZEUS. (orig.)

  5. History of Maternity and Infancy in Zemsky Period (Based on the Central Chernozem (Black Earth Region Files

    Directory of Open Access Journals (Sweden)

    Anna S. Tretyak

    2015-03-01

    Full Text Available The paper presents a brief historical overview of the evolution of maternal and child health care in Russia. A system of Public Health Service in the Central Black Earth Region governments (territorial subdivisions of Russia, 1708-1929 is taken as an example. A retrospective of the review is limited to the last third of the XIX century. The paper discusses historical aspects of the problem, which are mainly concentrated in the first quarter of the XX century. Organizational aspects of the medical staff training, problems with the obstetric aid organization are also considered. Characteristics of the governments in their activity to fight with infant mortality are stated in the paper.

  6. Model-Based Radiation Dose Correction for Yttrium-90 Microsphere Treatment of Liver Tumors With Central Necrosis

    International Nuclear Information System (INIS)

    Liu, Ching-Sheng; Lin, Ko-Han; Lee, Rheun-Chuan; Tseng, Hsiou-Shan; Wang, Ling-Wei; Huang, Pin-I; Chao, Liung-Sheau; Chang, Cheng-Yen; Yen, Sang-Hue; Tung, Chuan-Jong; Wang, Syh-Jen; Oliver Wong, Ching-yee; Liu, Ren-Shyan

    2011-01-01

    Purpose: The objectives of this study were to model and calculate the absorbed fraction φ of energy emitted from yttrium-90 ( 90 Y) microsphere treatment of necrotic liver tumors. Methods and Materials: The tumor necrosis model was proposed for the calculation of φ over the spherical shell region. Two approaches, the semianalytic method and the probabilistic method, were adopted. In the former method, the range--energy relationship and the sampling of electron paths were applied to calculate the energy deposition within the target region, using the straight-ahead and continuous-slowing-down approximation (CSDA) method. In the latter method, the Monte Carlo PENELOPE code was used to verify results from the first method. Results: The fraction of energy, φ, absorbed from 90 Y by 1-cm thickness of tumor shell from microsphere distribution by CSDA with complete beta spectrum was 0.832 ± 0.001 and 0.833 ± 0.001 for smaller (r T = 5 cm) and larger (r T = 10 cm) tumors (where r is the radii of the tumor [T] and necrosis [N]). The fraction absorbed depended mainly on the thickness of the tumor necrosis configuration, rather than on tumor necrosis size. The maximal absorbed fraction φ that occurred in tumors without central necrosis for each size of tumor was different: 0.950 ± 0.000, and 0.975 ± 0.000 for smaller (r T = 5 cm) and larger (r T = 10 cm) tumors, respectively (p 90 Y microsphere treatment of hepatic tumors with central necrosis. With this model, important information is provided regarding the absorbed fraction applicable to clinical 90 Y microsphere treatment.

  7. Historical reconstruction of atmospheric lead pollution in central Yunnan province, southwest China: an analysis based on lacustrine sedimentary records.

    Science.gov (United States)

    Liu, Enfeng; Zhang, Enlou; Li, Kai; Nath, Bibhash; Li, Yanling; Shen, Ji

    2013-12-01

    Atmospheric lead (Pb) pollution during the last century in central Yunnan province, one of the largest non-ferrous metal production centers in China, was reconstructed using sediment cores collected from Fuxian and Qingshui Lakes. Lead concentrations and isotopic ratios ((207)Pb/(206)Pb and (208)Pb/(206)Pb) were measured in sediment cores from both lakes. The operationally defined chemical fractions of Pb in sediment core from Fuxian Lake were determined by the optimized BCR procedure. The chronology of the cores was reconstructed using (210)Pb and (137)Cs dating methods. Similar three-phase variations in isotopic ratios and enrichment factors of Pb were observed in the sediment cores from both lakes. Before the 1950s, the sediment data showed low (207)Pb/(206)Pb and (208)Pb/(206)Pb ratios and enrichment factors (EFs=~1), indicating that the sedimentary Pb was predominantly of lithogenic origin. However, these indices were increased gradually between the 1950s and the mid-1980s, implying an atmospheric Pb deposition. The EFs and isotopic ratios of Pb reached their peak during recent years, indicating aggravating atmospheric Pb pollution. The average anthropogenic Pb fluxes since the mid-1980s were estimated to be 0.032 and 0.053 g m(-2) year(-1) recorded in Fuxian and Qingshui cores, respectively. The anthropogenic Pb was primarily concentrated in the reducible fraction. Combining the results of Pb isotopic compositions and chemical speciations in the sediment cores and in potential sources, we deduced that recent aggravating atmospheric Pb pollution in central Yunnan province should primarily be attributed to regional emissions from non-ferrous metal production industries.

  8. Origin and evolution of Sariñena Lake (central Ebro Basin): A piping-based model

    Science.gov (United States)

    Castañeda, Carmen; Javier Gracia, F.; Rodríguez-Ochoa, Rafael; Zarroca, Mario; Roqué, Carles; Linares, Rogelio; Desir, Gloria

    2017-08-01

    The origin and nature of the numerous lakes in the central Ebro Basin have been interpreted according to the prevailing arid or semiarid conditions, the easily-eroded materials and the solubility of the gypsum- and/or carbonate-rich Tertiary/Cenozoic substratum, involving important dissolution (karstic) and/or aeolian deflation. However, the origin of Sariñena Lake, the largest in the central Ebro Basin, remains unknown since the typical lake-generating processes in the region are not applicable. This work provides significant clues to the genesis and evolution of Sariñena Lake in a regional context. The combination of geomorphological mapping and high resolution LiDAR data together with sedimentological observations, the characterisation of soils and sediments around the lake, and the application of high-resolution geophysical techniques suggest that piping is the major genetic process driving the evolution of the Sariñena depression and lake. Field evidence demonstrates that piping is, at present, the most important erosive process in the region, generating significant collapse and surface lowering. Sariñena Lake is located within a deep endorheic depression excavated from Na-rich Tertiary materials. This work hypothesises that once an early, fluvially-originated palustrine area had developed, the progressive lowering of the regional water table linked to regional fluvial incision favoured the establishment of a hydrological gradient high enough to trigger piping processes within the claystones and siltstones underlying the original palustrine area. The Quaternary evolution of the Sariñena lacustrine basin was then controlled by successive water table fluctuations, linked to different phases of incision and alluvial deposition in the surrounding fluvial systems. All the evidence supporting a piping-related origin for this lake, together with examples of lakes generated by similar processes in different contexts, is used to propose a new genetic type of

  9. Evaluation of the Surface Water Distribution in North-Central Namibia Based on MODIS and AMSR Series

    Directory of Open Access Journals (Sweden)

    Hiroki Mizuochi

    2014-08-01

    Full Text Available Semi-arid North-central Namibia has high potential for rice cultivation because large seasonal wetlands (oshana form during the rainy season. Evaluating the distribution of surface water would reveal the area potentially suitable for rice cultivation. In this study, we detected the distribution of surface water with high spatial and temporal resolution by using two types of complementary satellite data: MODIS (MODerate-resolution Imaging Spectroradiometer and AMSR-E (Advanced Microwave Scanning Radiometer–Earth Observing System, using AMSR2 after AMSR-E became unavailable. We combined the modified normalized-difference water index (MNDWI from the MODIS data with the normalized-difference polarization index (NDPI from the AMSR-E and AMSR2 data to determine the area of surface water. We developed a simple gap-filling method (“database unmixing” with the two indices, thereby providing daily 500-m-resolution MNDWI maps of north-central Namibia regardless of whether the sky was clear. Moreover, through receiver-operator characteristics (ROC analysis, we determined the threshold MNDWI (−0.316 for wetlands. Using ROC analysis, MNDWI had moderate performance (the area under the ROC curve was 0.747, and the recognition error for seasonal wetlands and dry land was 21.2%. The threshold MNDWI let us calculate probability of water presence (PWP maps for the rainy season and the whole year. The PWP maps revealed the total area potentially suitable for rice cultivation: 1255 km2 (1.6% of the study area.

  10. Assessment of village-wise groundwater draft for irrigation: a field-based study in hard-rock aquifers of central India

    Science.gov (United States)

    Ray, R. K.; Syed, T. H.; Saha, Dipankar; Sarkar, B. C.; Patre, A. K.

    2017-12-01

    Extracted groundwater, 90% of which is used for irrigated agriculture, is central to the socio-economic development of India. A lack of regulation or implementation of regulations, alongside unrecorded extraction, often leads to over exploitation of large-scale common-pool resources like groundwater. Inevitably, management of groundwater extraction (draft) for irrigation is critical for sustainability of aquifers and the society at large. However, existing assessments of groundwater draft, which are mostly available at large spatial scales, are inadequate for managing groundwater resources that are primarily exploited by stakeholders at much finer scales. This study presents an estimate, projection and analysis of fine-scale groundwater draft in the Seonath-Kharun interfluve of central India. Using field surveys of instantaneous discharge from irrigation wells and boreholes, annual groundwater draft for irrigation in this area is estimated to be 212 × 106 m3, most of which (89%) is withdrawn during non-monsoon season. However, the density of wells/boreholes, and consequent extraction of groundwater, is controlled by the existing hydrogeological conditions. Based on trends in the number of abstraction structures (1982-2011), groundwater draft for the year 2020 is projected to be approximately 307 × 106 m3; hence, groundwater draft for irrigation in the study area is predicted to increase by ˜44% within a span of 8 years. Central to the work presented here is the approach for estimation and prediction of groundwater draft at finer scales, which can be extended to critical groundwater zones of the country.

  11. Validation of a semi-automatic protocol for the assessment of the tear meniscus central area based on open-source software

    Science.gov (United States)

    Pena-Verdeal, Hugo; Garcia-Resua, Carlos; Yebra-Pimentel, Eva; Giraldez, Maria J.

    2017-08-01

    Purpose: Different lower tear meniscus parameters can be clinical assessed on dry eye diagnosis. The aim of this study was to propose and analyse the variability of a semi-automatic method for measuring lower tear meniscus central area (TMCA) by using open source software. Material and methods: On a group of 105 subjects, one video of the lower tear meniscus after fluorescein instillation was generated by a digital camera attached to a slit-lamp. A short light beam (3x5 mm) with moderate illumination in the central portion of the meniscus (6 o'clock) was used. Images were extracted from each video by a masked observer. By using an open source software based on Java (NIH ImageJ), a further observer measured in a masked and randomized order the TMCA in the short light beam illuminated area by two methods: (1) manual method, where TMCA images was "manually" measured; (2) semi-automatic method, where TMCA images were transformed in an 8-bit-binary image, then holes inside this shape were filled and on the isolated shape, the area size was obtained. Finally, both measurements, manual and semi-automatic, were compared. Results: Paired t-test showed no statistical difference between both techniques results (p = 0.102). Pearson correlation between techniques show a significant positive near to perfect correlation (r = 0.99; p Conclusions: This study showed a useful tool to objectively measure the frontal central area of the meniscus in photography by free open source software.

  12. Effects of seasonal variability in across- and alongshore transport of anchoveta ( Engraulis ringens) larvae on model-based pre-recruitment indices off central Chile

    Science.gov (United States)

    Parada, Carolina; Colas, Francois; Soto-Mendoza, Samuel; Castro, Leonardo

    2012-01-01

    An individual-based model (IBM) of anchoveta ( Engraulis ringens) larvae was coupled to a climatological hydrodynamic (Regional Oceanic Modeling System, ROMS) model for central-southern Chile to answer the question as to whether or not across- and alongshore transport off central-southern Chile enhances retention in the spawning areas during the winter and summer reproductive periods, using model-based pre-recruitment indices (simulated transport success to nursery areas). The hydrodynamic model validation showed that ROMS captures the mean Seas Surface Temperature and Eddie Kinetic Energy observed in satellite-based data over the entire region. The IBM was used to simulate the transport of eggs and larvae from spawning zones in central Chile (Constitución, Dichato, Gulf of Arauco and Lebu-Corral) to historical nursery areas (HRZ, region between 35°S and 37°S). Model results corroborated HRZ as the most successful pre-recruitment zone (particles originated in the Dichato and Gulf of Arauco spawning areas), as well as identifying Lebu-Corral as a zone of high retention with a high associated pre-recruitment index (particles originated in the Lebu-Corral spawning zone). The highest pre-recruitment values were mainly found in winter. The Constitución and Dichato spawning zones displayed a typical summer upwelling velocity pattern, while the Gulf of Arauco in summertime showed strong offshore and alongshore velocity components. The Lebu-Corral region in winter presented important near-surface cross-shore transport towards the coast (associated with downwelling events), this might be one of the major mechanisms leading to high retention levels and a high pre-recruitment index for Lebu-Corral spawning zone. The limitations of the modeling approach are discussed and put into perspective for future work.

  13. Mechanisms-based classifications of musculoskeletal pain: part 1 of 3: symptoms and signs of central sensitisation in patients with low back (± leg) pain.

    LENUS (Irish Health Repository)

    Smart, Keith M

    2012-08-01

    As a mechanisms-based classification of pain \\'central sensitisation pain\\' (CSP) refers to pain arising from a dominance of neurophysiological dysfunction within the central nervous system. Symptoms and signs associated with an assumed dominance of CSP in patients attending for physiotherapy have not been extensively studied. The purpose of this study was to identify symptoms and signs associated with a clinical classification of CSP in patients with low back (± leg) pain. Using a cross-sectional, between-subjects design; four hundred and sixty-four patients with low back (± leg) pain were assessed using a standardised assessment protocol. Patients\\' pain was assigned a mechanisms-based classification based on experienced clinical judgement. Clinicians then completed a clinical criteria checklist specifying the presence or absence of various clinical criteria. A binary logistic regression analysis with Bayesian model averaging identified a cluster of three symptoms and one sign predictive of CSP, including: \\'Disproportionate, non-mechanical, unpredictable pattern of pain provocation in response to multiple\\/non-specific aggravating\\/easing factors\\

  14. central t

    Directory of Open Access Journals (Sweden)

    Manuel R. Piña Monarrez

    2007-01-01

    Full Text Available Dado que la Regresión Ridge (RR, es una estimación sesgada que parte de la solución de la regresión de Mínimos Cuadrados (MC, es vital establecer las condiciones para las que la distribución central t de Student que se utiliza en la prueba de hipótesis en MC, sea también aplicable a la regresión RR. La prueba de este importante resultado se presenta en este artículo.

  15. Central sleep apnea

    Science.gov (United States)

    Sleep apnea - central; Obesity - central sleep apnea; Cheyne-Stokes - central sleep apnea; Heart failure - central sleep apnea ... Central sleep apnea results when the brain temporarily stops sending signals to the muscles that control breathing. The condition ...

  16. Soil quality assessment using GIS-based chemometric approach and pollution indices: Nakhlak mining district, Central Iran.

    Science.gov (United States)

    Moore, Farid; Sheykhi, Vahideh; Salari, Mohammad; Bagheri, Adel

    2016-04-01

    This paper is a comprehensive assessment of the quality of soil in the Nakhlak mining district in Central Iran with special reference to potentially toxic metals. In this regard, an integrated approach involving geostatistical, correlation matrix, pollution indices, and chemical fractionation measurement is used to evaluate selected potentially toxic metals in soil samples. The fractionation of metals indicated a relatively high variability. Some metals (Mo, Ag, and Pb) showed important enrichment in the bioavailable fractions (i.e., exchangeable and carbonate), whereas the residual fraction mostly comprised Sb and Cr. The Cd, Zn, Co, Ni, Mo, Cu, and As were retained in Fe-Mn oxide and oxidizable fractions, suggesting that they may be released to the environment by changes in physicochemical conditions. The spatial variability patterns of 11 soil heavy metals (Ag, As, Cd, Co, Cr, Cu, Mo, Ni, Pb, Sb, and Zn) were identified and mapped. The results demonstrated that Ag, As, Cd, Mo, Cu, Pb, Sb, and Zn pollution are associated with mineralized veins and mining operations in this area. Further environmental monitoring and remedial actions are required for management of soil heavy metals in the study area. The present study not only enhanced our knowledge regarding soil pollution in the study area but also introduced a better technique to analyze pollution indices by multivariate geostatistical methods.

  17. Conditions for the adoption of conservation agriculture in Central Morocco: an approach based on Bayesian network modelling

    Directory of Open Access Journals (Sweden)

    Laura Bonzanigo

    2016-03-01

    Full Text Available Research in Central Morocco, proves that conservation agriculture increases yields, reduces labour requirements, and erosion, and improves soil fertility. However, after nearly two decades of demonstration and advocacy, adoption is still limited. This paper investigates the critical constraints and potential opportunities for the adoption of conservation agriculture for different typologies of farms. We measured the possible pathways of adoption via a Bayesian decision network (BDN. BDNs allow the inclusion of stakeholders’ knowledge where data is scant, whilst at the same time they are supported by a robust mathematical background. We first developed a conceptual map of the elements affecting the decision about tillage, which we refined in a workshop with farmers and researchers from the Settat area. We then involved experts in the elicitation of conditional probabilities tables, to quantify the cascade of causal links that determine (or not the adoption. Via BDNs, we could categorise under which specific technical and socio-economic conditions no tillage agriculture is best suited to which farmers. We, by identifying the main constraints and running sensitivity analyses, were able to convey clear messages on how policy- makers may facilitate the conversion. As new evidence is collected, the BDN can be updated to obtain evidence more targeted and fine tuned to the adoption contexts.

  18. AGRO-ECOLOGICAL AND SOCIO-ECONOMIC ASPECTS OF CROP PROTECTION IN CHILI-BASED AGRIBUSINESS IN CENTRAL JAVA

    Directory of Open Access Journals (Sweden)

    Joko Mariyono

    2017-11-01

    Full Text Available The purpose of this study is to analyze the socio-economic and agro-ecological aspects of chili production in three selected communities of three districts —Magelang, Brebes, and Rembang—that represent distinct agro-ecosystems of chili cultivation within Central Java province. This is to answer a problem statement that chili farming still faces crop protection aspects as limiting factors in chili production. This study uses quantitative descriptive methods. Data were compiled from a survey of 160 chili farmers in 2010-2011. The results show that yield loss due to pests and diseases was considerable, and some of these problems were becoming difficult to control. The three top pests were thrips, mites, and whitefly; and the top three diseases were Anthracnose, Gemini-viruses, and Phytophthora. During the wet season, risk of anthracnose was very high; in the dry season, risk of yield lost to Gemini-viruses and Phytophthora was high. The potential losses could reach 100%. There is a crucial need to solve the problems by enhancing farmers’ knowledge and involving research institutions focusing on crop protection strategy.

  19. Development of Kubłowo Palaeolake in Central Poland During Eemian Based on Subfossil Cladocera Analysis – Preliminary Results

    Directory of Open Access Journals (Sweden)

    Niska Monika

    2014-04-01

    Full Text Available The results of analysis of Cladocera occurrence in lacustrine sediments from the Kubłowo site have been presented. Lacustrine and peat deposits found there have been previously an analyzed for pollen content (depth of 11.1-3.8 m and represent a longest continuous Eemian-Vistulian succession in central Po land (Roman and Balwierz, 2010. Cladocera analysis was carried out on 25 samples from the depth of 9.20-10.5 m of an Eemian age section. The section consists of fine organic sand, silt with organic matter and gyttja. Identified were 19 species of subfossil Cladocera and five zones of fauna development were distinguished. In the early and mid-Eemian low frequency zooplankton in the palaeolake has been found. Best conditions for zooplankton development occurred in the late Eemian (R PAZ E6, E7. At the end of the Eemian a significant change of climate in a deterioration of environmental conditions and decreased presence of zoo plank ton has been noted. Cladocera results and the pollen data enable a reconstruction of the climatic and environmental changes in the Kubłowo palaeolake.

  20. Investigation on Fuzzy Logic Based Centralized Control in Four-Port SEPIC/ZETA Bidirectional Converter for Photovoltaic Applications

    Directory of Open Access Journals (Sweden)

    VENMATHI, M.

    2016-02-01

    Full Text Available In this paper, a new four-port DC-DC converter topology is proposed to interface renewable energy sources and the load along with the energy storage device. The proposed four-port SEPIC/ZETA bidirectional converter (FP-SEPIC/ZETA BDC converter comprises an isolated output port with two unidirectional and one bidirectional input ports. This converter topology is obtained by the fusion of SEPIC/ZETA BDC and full-bridge converter. This converter topology ensures the non-reversal of output voltage hence it is preferred mostly for battery charging applications. In this work, photovoltaic (PV source is considered and the power balance in the system is achieved by means of distributed maximum power point tracking (DMPPT in the PV ports. The centralized controller is implemented using fuzzy logic controller (FLC and the performance is compared with conventional proportional integral (PI controller. The results offer useful information to obtain the desired output under line and load regulations. Experimental results are also provided to validate the simulation results.

  1. Internal tectonic structure of the Central American Wadati-Benioff zone based on analysis of aftershock sequences

    Science.gov (United States)

    Špičák, Aleš; Hanuš, Václav; Vaněk, Jiří; Běhounková, Marie

    2007-09-01

    Relocated Engdahl et al. (1998) global seismological data for 10 aftershock sequences were used to analyze the internal tectonic structure of the Central American subduction zone; the main shocks of several of these were the most destructive and often referenced earthquakes in the region (e.g., the 1970 Chiapas, 1983 Osa, 1992 Nicaragua, 1999 Quepos, 2001 El Salvador earthquakes). The spatial analysis of aftershock foci distribution was performed in a rotated Cartesian coordinate system (x, y, z) related to the Wadati-Benioff zone, and not in a standard coordinate system ($\\varphi$, λ, h are latitude, longitude, focal depth, respectively). Available fault plane solutions were also transformed into the plane approximating the Wadati-Benioff zone. The spatial distribution of earthquakes in each aftershock sequence was modeled as either a plane fit using a least squares approximation or a volume fit with a minimum thickness rectangular box. The analysis points to a quasi-planar distribution of earthquake foci in all aftershock sequences, manifesting the appurtenance of aftershocks to fracture zones. Geometrical parameters of fracture zones (strike, dip, and dimensions) hosting individual sequences were calculated and compared with the seafloor morphology of the Cocos Plate. The smooth character of the seafloor correlates with the aftershock fracture zones oriented parallel to the trench and commonly subparallel to the subducting slab, whereas subduction of the Cocos Ridge and seamounts around the Quepos Plateau coincides with steeply dipping fracture zones. Transformed focal mechanisms are almost exclusively (>90%) of normal character.

  2. AFSC/NMML: Shore-based counts of the Eastern North Pacific gray whale stock from central California, 1967 - 2007

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Marine Fisheries Service (NMFS) has conducted shore-based counts of the Eastern North Pacific stock of gray whales (Eschrichtius robustus) 26 years from...

  3. Historia de la creación de la banca central latinoamericana -El pretérito es la base de un presente prominente-

    Directory of Open Access Journals (Sweden)

    Roberto Vinicio Posso Ordóñez

    2016-07-01

    Full Text Available El dinero desempeña tres funciones principales: la primera es servir como medio de cambio, cuando lo utilizamos para comprar bienes y servicios. El trueque es muy ineficiente porque exige una coincidencia de necesidades y deseos entre oferentes y demandantes. La segunda función es la de servir como unidad de cuenta, es decir permite realizar fácilmente comparaciones de valor entre bienes, a través de los precios. La tercera función es como depósito de valor. No obstante, el dinero no es la única forma de “tener” riqueza (depósito de valor. Sin embargo el dinero en efectivo tiene la ventaja de que es difícil de “seguirle la pista” ya que es anónimo, pero la inflación hace que se pierda la riqueza. El dinero tiene un valor nominal superior al valor intrínseco de su contenido en metal o papel. Es por esta razón que el factor confianza (del latín fiducia es la base para que funcione eficientemente un sistema monetario moderno. Esa necesaria confianza fue perdiéndose cuando la banca privada, que era la que emitía los valores fiduciarios (monedas y billetes, lo hacía sin tener ningún respaldo físico (de oro o plata y en consecuencia le correspondió al Estado asumir la responsabilidad de restablecer esa confianza y credibilidad en el dinero. Por esto es necesaria la existencia y funcionamiento de la banca central. En esta investigación se relata la historia de la creación de la banca central Latinoamericana, para lo cual iniciaremos con una breve introducción para referirnos a la aparición, alrededor de 5.000 años atrás, de los primeros bancos. Describiremos lo ocurrido en Inglaterra y España con relación a la creación de los bancos centrales en esas naciones, por la influencia que tuvieron esos países en América Latina. Luego haremos un breve recuento de lo ocurrido entre los siglos XVII y XX, periodo en el cual aparece en el mundo la banca central. Finalmente abordaremos sobre la creación de los bancos

  4. Risk communication and gender based violence: a case of child marriage and obstetric fistula in North Central Nigeria

    OpenAIRE

    Oramah, Chinwe Philomina

    2015-01-01

    Master's thesis in Risk management and societal safety Gender based violence, often targeted against girl children in the name of child marriage has profound health problems, compromising victim’s physical and mental health as well as eroding their self-esteem. In addition to causing physical health problems, it is the most pervasive human rights violation in the world. Yet most of the gender based violent acts enjoy much socio-cultural support. Researches have shown increasing link betwee...

  5. Modelling central metabolic fluxes by constraint-based optimization reveals metabolic reprogramming of developing Solanum lycopersicum (tomato) fruit.

    Science.gov (United States)

    Colombié, Sophie; Nazaret, Christine; Bénard, Camille; Biais, Benoît; Mengin, Virginie; Solé, Marion; Fouillen, Laëtitia; Dieuaide-Noubhani, Martine; Mazat, Jean-Pierre; Beauvoit, Bertrand; Gibon, Yves

    2015-01-01

    Modelling of metabolic networks is a powerful tool to analyse the behaviour of developing plant organs, including fruits. Guided by our current understanding of heterotrophic metabolism of plant cells, a medium-scale stoichiometric model, including the balance of co-factors and energy, was constructed in order to describe metabolic shifts that occur through the nine sequential stages of Solanum lycopersicum (tomato) fruit development. The measured concentrations of the main biomass components and the accumulated metabolites in the pericarp, determined at each stage, were fitted in order to calculate, by derivation, the corresponding external fluxes. They were used as constraints to solve the model by minimizing the internal fluxes. The distribution of the calculated fluxes of central metabolism were then analysed and compared with known metabolic behaviours. For instance, the partition of the main metabolic pathways (glycolysis, pentose phosphate pathway, etc.) was relevant throughout fruit development. We also predicted a valid import of carbon and nitrogen by the fruit, as well as a consistent CO2 release. Interestingly, the energetic balance indicates that excess ATP is dissipated just before the onset of ripening, supporting the concept of the climacteric crisis. Finally, the apparent contradiction between calculated fluxes with low values compared with measured enzyme capacities suggest a complex reprogramming of the metabolic machinery during fruit development. With a powerful set of experimental data and an accurate definition of the metabolic system, this work provides important insight into the metabolic and physiological requirements of the developing tomato fruits. © 2014 The Authors The Plant Journal published by Society for Experimental Biology and John Wiley & Sons Ltd.

  6. Identification of mineralized zones in the Zardu area, Kushk SEDEX deposit (Central Iran, based on geological and multifractal modeling

    Directory of Open Access Journals (Sweden)

    Dahooei Ahmad Heidari

    2016-02-01

    Full Text Available The aim of this paper is to delineate the different lead–zinc mineralized zones in the Zardu area of the Kushk zinc–lead stratabound SEDEX deposit, Central Iran, through concentration–volume (C–V modeling of geological and lithogeochemical drillcore data. The geological model demonstrated that the massive sulfide and pyrite+dolomite ore types as main rock types hosting mineralization. The C–V fractal modeling used lead, zinc and iron geochemical data to outline four types of mineralized zones, which were then compared to the mineralized rock types identified in the geological model. ‘Enriched’ mineralized zones contain lead and zinc values higher than 6.93% and 19.95%, respectively, with iron values lower than 12.02%. Areas where lead and zinc values were higher than 1.58% and 5.88%, respectively, and iron grades lower than 22% are labelled “high-grade” mineralized zones, and these zones are linked to massive sulfide and pyrite+dolomite lithologies of the geological model. Weakly mineralized zones, labelled ‘low-grade’ in the C– V model have 0–0.63% lead, 0–3.16% zinc and > 30.19% iron, and are correlated to those lithological units labeled as gangue in the geological model, including shales and dolomites, pyritized dolomites. Finally, a log-ratio matrix was employed to validate the results obtained and check correlations between the geological and fractal modeling. Using this method, a high overall accuracy (OA was confirmed for the correlation between the enriched and high-grade mineralized zones and two lithological units — the massive sulfide and pyrite+dolomite ore types.

  7. Central hypothyroidism

    Directory of Open Access Journals (Sweden)

    Vishal Gupta

    2011-01-01

    Full Text Available Central hypothyroidism is defined as hypothyroidism due to insufficient stimulation by thyroid stimulating hormone (TSH of an otherwise normal thyroid gland. It has an estimated prevalence of approximately 1 in 80,000 to 1 in 120,000. It can be secondary hypothyroidism (pituitary or tertiary hypothyroidism (hypothalamus in origin. In children, it is usually caused by craniopharyngiomas or previous cranial irradiation for brain tumors or hematological malignancies. In adults, it is usually due to pituitary macroadenomas, pituitary surgeries or post-irradiation. Fatigue and peripheral edema are the most specific clinical features. Diagnosis is established by the presence of normal to low-normal TSH on the background of low-normal thyroid hormones, confirmed by the thyrotropin releasing hormone stimulation test. Therapy includes use of levothyroxine titrated to improvement in symptomology and keeping free T4 in the upper limit of normal reference range.

  8. Assessing suitable area for Acacia dealbata Mill. in the Ceira River Basin (Central Portugal based on maximum entropy modelling approach

    Directory of Open Access Journals (Sweden)

    Jorge Pereira

    2015-12-01

    Full Text Available Biological invasion by exotic organisms became a key issue, a concern associated to the deep impacts on several domains described as resultant from such processes. A better understanding of the processes, the identification of more susceptible areas, and the definition of preventive or mitigation measures are identified as critical for the purpose of reducing associated impacts. The use of species distribution modeling might help on the purpose of identifying areas that are more susceptible to invasion. This paper aims to present preliminary results on assessing the susceptibility to invasion by the exotic species Acacia dealbata Mill. in the Ceira river basin. The results are based on the maximum entropy modeling approach, considered one of the correlative modelling techniques with better predictive performance. Models which validation is based on independent data sets present better performance, an evaluation based on the AUC of ROC accuracy measure.

  9. Physically-Based Modelling of the Post-Fire Runoff Response of a Forest Catchment in Central Portugal

    NARCIS (Netherlands)

    Eck, Van Christel M.; Nunes, Joao P.; Vieira, Diana C.S.; Keesstra, Saskia; Keizer, Jan Jacob

    2016-01-01

    Forest fires are a recurrent phenomenon in Mediterranean forests, with impacts for human landscapes and communities, which must be understood before they can be managed. This study used the physically based Limburg Soil Erosion Model (LISEM) to simulate rainfall–runoff response, under soil water

  10. Contributions of separate reactions to the acid-base buffering of soils in brook floodplains (Central Forest State Reserve)

    Science.gov (United States)

    Sokolova, T. A.; Tolpeshta, I. I.; Rusakova, E. S.

    2016-04-01

    The acid-base buffering of gleyic gray-humus soils developed in brook floodplains and undisturbed southern-taiga landscapes has been characterized by the continuous potentiometric titration of soil water suspensions. During the interaction with an acid, the major amount of protons (>80%) is consumed for the displacement of exchangeable bases and the dissolution of Ca oxalates. In the O and AY horizons, Mn compounds make the major contribution (2-15%) to the acid buffering. The buffer reactions with the participation of Al compounds make up from 0.5 to 1-2% of the total buffering capacity, and the protonation of the surface OH groups of kaolinite consumes 2-3% of the total buffering capacity. The deprotonation of OH groups on the surface of Fe hydroxides (9-43%), the deprotonation of OH groups on the surface of illite crystals (3-19%), and the dissolution of unidentified aluminosilicates (9-14%) are the most significant buffer reactions whose contributions have been quantified during the interaction with a base. The contribution of the deprotonation of OH groups on the surface of kaolinite particles is lower (1-5%) because of the small specific surface area of this mineral, and that of the dissolution of Fe compounds is insignificant. In the AY horizon, the acid and base buffering of soil in the rhizosphere is higher than beyond the rhizosphere because of the higher contents of organic matter and nonsilicate Fe and Al compounds.

  11. How Transparent About its Inflation Target Should a Central Bank be? An Agent-Based Model Assessment

    NARCIS (Netherlands)

    Salle, I.; Sénégas, M.A.; Yıldızoğlu, M.

    2013-01-01

    This paper revisits the benefits of explicitly announcing an inflation target for the con- duct of monetary policy in the framework of an agent-based model (ABM). This framework offers a flexible tool for modeling heterogeneity among individual agents and their bounded rationality, and to emphasize,

  12. Central Station Design Options

    DEFF Research Database (Denmark)

    2011-01-01

    . The work identifies the architecture, sizing and siting of prospective Central Stations in Denmark, which can be located at shopping centers, large car parking lots or gas stations. Central Stations are planned to be integrated in the Danish distribution grid. The Danish island of Bornholm, where a high...... overloading, more reference points might be necessary to represent various transformer loading levels. The subject of safety in Central Station is also addressed. A number of safety rules based on European standards apply to AC charging equipment up to 44 kW. The connection interlock and the automatic de......-energization are identified as fundamental requirements for safety in such a charging station. The connection interlock is a solution which ensures that no power is applied to the DC cable when the EV connector is not connected. The automatic de-energization device ensures that whenever a strain on the cable is detected, e...

  13. DEM-based delineation for improving geostatistical interpolation of rainfall in mountainous region of Central Himalayas, India

    Science.gov (United States)

    Kumari, Madhuri; Singh, Chander Kumar; Bakimchandra, Oinam; Basistha, Ashoke

    2017-10-01

    In mountainous region with heterogeneous topography, the geostatistical modeling of the rainfall using global data set may not confirm to the intrinsic hypothesis of stationarity. This study was focused on improving the precision of the interpolated rainfall maps by spatial stratification in complex terrain. Predictions of the normal annual rainfall data were carried out by ordinary kriging, universal kriging, and co-kriging, using 80-point observations in the Indian Himalayas extending over an area of 53,484 km2. A two-step spatial clustering approach is proposed. In the first step, the study area was delineated into two regions namely lowland and upland based on the elevation derived from the digital elevation model. The delineation was based on the natural break classification method. In the next step, the rainfall data was clustered into two groups based on its spatial location in lowland or upland. The terrain ruggedness index (TRI) was incorporated as a co-variable in co-kriging interpolation algorithm. The precision of the kriged and co-kriged maps was assessed by two accuracy measures, root mean square error and Chatfield's percent better. It was observed that the stratification of rainfall data resulted in 5-20 % of increase in the performance efficiency of interpolation methods. Co-kriging outperformed the kriging models at annual and seasonal scale. The result illustrates that the stratification of the study area improves the stationarity characteristic of the point data, thus enhancing the precision of the interpolated rainfall maps derived using geostatistical methods.

  14. Risk Mapping and Situational Analysis of Cutaneous Leishmaniasis in an Endemic Area of Central Iran: A GIS-Based Survey.

    Science.gov (United States)

    Abedi-Astaneh, Fatemeh; Hajjaran, Homa; Yaghoobi-Ershadi, Mohammad Reza; Hanafi-Bojd, Ahmad Ali; Mohebali, Mehdi; Shirzadi, Mohammad Reza; Rassi, Yavar; Akhavan, Amir Ahmad; Mahmoudi, Bagher

    2016-01-01

    Cutaneous leishmaniasis (CL) is among the top 10 infectious disease priorities in the world, and the leading cause of morbidity in Iran. The present study was conducted to assess the risk of CL, and to determine some epidemiological features of the disease in endemic areas of Qom Province in Central Iran during 2009 to 2013. Data regarding human cases of the disease were obtained from the Qom Province Health Center, prepared and stored in a spatial database created in ArcGIS10.3. A total of 9 out of 212 Leishmania spp. positive slides taken in 2013 from patients residing in Qom city were examined using molecular methods and the species of Leishmania was identified by PCR-RFLP. Those 9 patients had no history of travel outside the city. Spatial analysis and clustering methods were applied to find major hot spots and susceptible areas for the establishment of novel foci of the disease. Transmission patterns were examined for spatial autocorrelation using the Moran's I statistical application, and for the clustering of high or low values using the Getis-Ord Gi* statistics. During the period of study, a total of 1767 CL cases were passively reported in the area, out of which were 65% males and 35% females. The highest and lowest numbers of cases were reported in 2010 and 2013, respectively. Importantly, 979 cases were reported from urban areas, while the remainder came from rural areas. Leishmania major was detected as the causative agent of CL in the city of Qom. Remarkably, most patients recorded in Qom city were associated with a history of travel to the endemic areas of CL within the province, or to other endemic areas of the disease in Iran. Spatial distribution of CL cases revealed northeastern and southwestern quarters of the city were the major hot spots of the disease (P<0.05). Hot spot and CL transmission risk analysis across the province indicated that more than 40 villages were located in high and very high risk areas of CL transmission. Due to the

  15. Exploiting Growing Stock Volume Maps for Large Scale Forest Resource Assessment: Cross-Comparisons of ASAR- and PALSAR-Based GSV Estimates with Forest Inventory in Central Siberia

    Directory of Open Access Journals (Sweden)

    Christian Hüttich

    2014-07-01

    Full Text Available Growing stock volume is an important biophysical parameter describing the state and dynamics of the Boreal zone. Validation of growing stock volume (GSV maps based on satellite remote sensing is challenging due to the lack of consistent ground reference data. The monitoring and assessment of the remote Russian forest resources of Siberia can only be done by integrating remote sensing techniques and interdisciplinary collaboration. In this paper, we assess the information content of GSV estimates in Central Siberian forests obtained at 25 m from ALOS-PALSAR and 1 km from ENVISAT-ASAR backscatter data. The estimates have been cross-compared with respect to forest inventory data showing 34% relative RMSE for the ASAR-based GSV retrievals and 39.4% for the PALSAR-based estimates of GSV. Fragmentation analyses using a MODIS-based land cover dataset revealed an increase of retrieval error with increasing fragmentation of the landscape. Cross-comparisons of multiple SAR-based GSV estimates helped to detect inconsistencies in the forest inventory data and can support an update of outdated forest inventory stands.

  16. A revision of Meladema diving beetles (Coleoptera, Dytiscidae, with the description of a new species from the central Mediterranean based on molecules and morphology

    Directory of Open Access Journals (Sweden)

    David T. Bilton

    2017-09-01

    Full Text Available Meladema Laporte, 1835 are relatively large, stream-dwelling diving beetles, distributed widely in the Western Palaearctic, from the Atlantic Islands to Turkey, and from southern France and the Balkans to the central Sahara. In addition to the three previously recognised taxa (M. coriacea Laporte, 1835, M. imbricata (Wollaston, 1871 and M. lanio (Fabricius, 1775 we describe a new, cryptic, species from the central Mediterranean area, which can be distinguished from M. coriacea on both DNA sequence data and morphology, and provide a key to known species of the genus. Based on the study of genotyped material, both recent and archival, as well as the examination of a large number of museum specimens, we show that M. lepidoptera sp. n. occurs to the apparent exclusion of M. coriacea on Corsica, Sardinia and islands of the Tuscan Archipelago, but that both taxa are found in peninsular Italy, where they may occasionally hybridize. In the absence of the original type series, we designate a neotype for M. coriacea, and take the opportunity to designate a lectotype for M. lanio. Morphological variation in Meladema species is discussed, including that seen in known and presumed hybrids. Our study highlights the incomplete state of knowledge of Mediterranean biodiversity, even in relatively large, supposedly well-studied taxa.

  17. Use and Cost of Electronic Resources in Central Library of Ferdowsi University Based on E-metrics

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Davarpanah

    2012-07-01

    Full Text Available The purpose of this study was to investigate the usage of electronic journals in Ferdowsi University, Iran based on e-metrics. The paper also aimed to emphasize the analysis of cost-benefit and the correlation between the journal impact factors and the usage data. In this study experiences of Ferdowsi University library on licensing and usage of electronic resources was evaluated by providing a cost-benefit analysis based on the cost and usage statistics of electronic resources. Vendor-provided data were also compared with local usage data. The usage data were collected by tracking web-based access locally, and by collecting vender-provided usage data. The data sources were one-year of vendor-supplied e-resource usage data such as Ebsco, Elsevier, Proquest, Emerald, Oxford and Springer and local usage data collected from the Ferdowsi university web server. The study found that actual usage values differ for vendor-provided data and local usage data. Elsevier has got the highest usage degree in searches, sessions and downloads. Statistics also showed that a small number of journals satisfy significant amount of use while the majority of journals were used less frequent and some were never used at all. The users preferred the PDF rather than HTML format. The data in subject profile suggested that the provided e-resources were best suited to certain subjects. There was no correlation between IF and electronic journal use. Monitoring the usage of e-resources gained increasing importance for acquisition policy and budget decisions. The article provided information about local metrics for the six surveyed vendors/publishers, e.g. usage trends, requests per package, cost per use as related to the scientific specialty of the university.

  18. Polyribosomes at the base of dendritic spines of central nervous system neurons - their possible role in synapse construction and modification

    International Nuclear Information System (INIS)

    Steward, O.

    1983-01-01

    The selective localization of polyribosomes at the base of dendritic spines in granule cells of the dentate gyrus was studied. These polyribosomes seem optimally situated to produce proteins for the postsynaptic membrane specialization or the spine and to have their synthetic activity regulated by functional activity over the synapse. The present work will summarize observations on the polyribosome clusters that were found to be ubiquitous in spines throughout the vertebrate CNS. Evidence will be presented that suggests a role for the polyribosomes in synapse construction and modification. 42 refs., 8 figs., 2 tabs

  19. Application of data mining techniques and data analysis methods to measure cancer morbidity and mortality data in a regional cancer registry: The case of the island of Crete, Greece.

    Science.gov (United States)

    Varlamis, Iraklis; Apostolakis, Ioannis; Sifaki-Pistolla, Dimitra; Dey, Nilanjan; Georgoulias, Vassilios; Lionis, Christos

    2017-07-01

    Micro or macro-level mapping of cancer statistics is a challenging task that requires long-term planning, prospective studies and continuous monitoring of all cancer cases. The objective of the current study is to present how cancer registry data could be processed using data mining techniques in order to improve the statistical analysis outcomes. Data were collected from the Cancer Registry of Crete in Greece (counties of Rethymno and Lasithi) for the period 1998-2004. Data collection was performed on paper forms and manually transcribed to a single data file, thus introducing errors and noise (e.g. missing and erroneous values, duplicate entries etc.). Data were pre-processed and prepared for analysis using data mining tools and algorithms. Feature selection was applied to evaluate the contribution of each collected feature in predicting patients' survival. Several classifiers were trained and evaluated for their ability to predict survival of patients. Finally, statistical analysis of cancer morbidity and mortality rates in the two regions was performed in order to validate the initial findings. Several critical points in the process of data collection, preprocessing and analysis of cancer data were derived from the results, while a road-map for future population data studies was developed. In addition, increased morbidity rates were observed in the counties of Crete (Age Standardized Morbidity/Incidence Rates ASIR= 396.45 ± 2.89 and 274.77 ±2.48 for men and women, respectively) compared to European and world averages (ASIR= 281.6 and 207.3 for men and women in Europe and 203.8 and 165.1 in world level). Significant variation in cancer types between sexes and age groups (the ratio between deaths and reported cases for young patients, less than 34 years old, is at 0.055 when the respective ratio for patients over 75 years old is 0.366) was also observed. This study introduced a methodology for preprocessing and analyzing cancer data, using a

  20. An artificial vision-based control system for automatic heliostat positioning offset correction in a central receiver solar power plant

    Energy Technology Data Exchange (ETDEWEB)

    Berenguel, M. [Universidad de Almeria, Dept. de Lenguajes y Computacion, La Canada Almeria (Spain); Rubio, F.R.; Lara, P.J.; Arahal, M.R.; Camacho, E.F.; Lopez, M. [Universidad de Sevilla, Dept. de Ingenieria de Sistemas y Automatica, Sevilla (Spain); Valverde, A. [Plataforma Solar de Almeria (PSA-CIEMAT), Tabernas (Almeria) (Spain)

    2004-07-01

    This paper presents the development of a simplified and automatic heliostat positioning offset correction control system using artificial vision techniques and common CCD devices. The heliostats of a solar power plant reflect solar radiation onto a receiver (in this case, a volumetric receiver) placed at the top of a tower in order to provide a desired energy flux distribution correlated with the coolant flow (in this case air mass flow) through the receiver, usually in an open loop control configuration. There exist error sources that increase the complexity of the control system, some of which are systematic ones, mainly due to tolerances, wrong mirror facets alignment (optical errors), errors due to the approximations made when calculating the solar position, etc., that produce errors (offsets) in the heliostat orientation (aiming point). The approximation adopted in this paper is based on the use of a B/W CCD camera to correct these deviations in an automatic way imitating the same procedure followed by the operators. The obtained images are used to estimate the distance between the sunbeam centroid projected by the heliostats and a target placed on the tower, this distance thus is used for low accuracy offset correction purposes. Basic threshold-based image processing techniques are used for automatic correction. (Author)

  1. Evidence-based innovative therapeutic medicine of Cretan plants: some encouraging specific functions and claims.

    Science.gov (United States)

    Lionis, Christos

    2015-01-01

    The Island of Crete was the place where the use of herbal medicine has its roots since the Bronze Age period. Although, the consumption of aromatic plants as component in curing common diseases is still on population's practices, a new interest was appeared on the basis of studies with a focus on illness behavior as a mutual collaboration between the University of Crete and the University of Leiden, The Netherlands. The antioxidant activity of certain Cretan plants has been documented and it has been shown and reported that herbal extracts are possible to decrease lipid per oxidation in cultured lung cells exposed to iron or ozon. The biological effects and bioactivity of essential oils as well as their antibacterial properties have been previously discussed in the literature. However, it was the first attempt in Europe when a double blind randomized controlled trial examined the effectiveness of an essential-oil extract of three Cretan aromatic plants (Origanum Dictamnus, Coridothymus Capitatus, Salvia Friticosa) designed and implemented in rural Crete on patients with upper respiratory tract infection. Descriptive differences were recently reported in favorable direction especially in the virus-positive population, while these results guide at the moment a series of actions for further research and discussion on the potentialities in the therapeutic medicine. An over-the-counter drug under the name of "Cretan Iama" and as soft-gel capsules has recently circulated in Greece by the Olvos Science SA. A recent joint attempt (Clinic of Social and Family Medicine and Department of Experimental Endocrinology at the School of Medicine, University of Crete) under the support of the National Strategic Reference Framework Program focused on the effectiveness of functional extract of Mentha Spicata encapsulated in yogurt with honey on lipids profile of health patients in rural Crete. The first reported results of a cross-over study which was designed and implemented recently

  2. Prenatal and Perinatal Morbidity in Children with Tic Disorders: A Mainstream School-based Population Study in Central Spain

    Directory of Open Access Journals (Sweden)

    Esther Cubo

    2014-12-01

    Full Text Available Background: While current research suggests that genetic factors confer the greatest risk for the development of tic disorders, studies of environmental factors are relatively few, with a lack of consistent risk factors across studies. Our aim is to analyze the association of tic disorders with exposure to prenatal and perinatal morbidity. Methods: This was a nested case–control study design. Cases and controls were selected and identified from a mainstream, school-based sample. The diagnosis of tic disorders was assigned by a movement disorder neurologist using ‘Diagnostic and statistical manual of mental disorders, 4th edition, text revision’ criteria, and neuropsychiatric comorbidities were screened using the Spanish computerized version of the Diagnostic Interview Schedule for Children Predictive Scale. Information regarding the exposure to pre-perinatal risk factors was collected by a retrospective review of the birth certificates. Logistic regression analyses were then performed to test the association of tic disorders with pre-perinatal risk factors.Results: Out of 407 participants, complete pre-perinatal data were available in 153 children (64 with tics and 89 without tics;. After adjusting for family history of tics, neonatal respiratory distress syndrome, body mass index, prenatal infection, and coexisting comorbid neuropsychiatric disturbances, tic disorders were associated with prenatal exposure to tobacco (odds ratio [OR] = 3.07, 95% confidence interval [CI] 1.24–7.60, p = 0.007, and cesarean section (OR = 5.78, 95% CI 1.60–20.91, p = 0.01.Discussion: This nested case–control study of children with tic disorders demonstrates higher adjusted odds for tics in children with exposure to cesarean delivery and maternal smoking. Longitudinal, population-based samples are required to confirm these results.

  3. Cervical human papilloma virus (HPV) DNA primary screening test: Results of a population-based screening programme in central Italy.

    Science.gov (United States)

    Passamonti, Basilio; Gustinucci, Daniela; Giorgi Rossi, Paolo; Cesarini, Elena; Bulletti, Simonetta; Carlani, Angela; Martinelli, Nadia; Broccolini, Massimo; D'Angelo, Valentina; D'Amico, Maria Rosaria; Di Dato, Eugenio; Galeazzi, Paola; Malaspina, Morena; Spita, Nicoletta; Tintori, Beatrice; Giaimo, Maria Donata

    2017-09-01

    Objective To present the results of the first and second round human papilloma virus (HPV)-based screening programme in the Umbria region after three years. Methods From August 2010 to November 2011, the entire female population aged 35-64 in a local health district was invited for HPV testing (HPV-DNA cobas4800 on a liquid-based cytology sample). HPV-negative women were re-invited after three years. For HPV-positive women, a slide was prepared and interpreted. Positive cytologies were referred to colposcopy; negatives were referred to repeat HPV after one year. If HPV was persistently positive, women were referred to colposcopy; if negative, to normal screening. Indicators of the first and second round are compared with those of cytology screening in the same area in the preceding three years. Results Participation was 56.5%, the same as cytology (56.6%). HPV-positivity was 6.4% (396/6272), cytology triage positivity was 35.6%; 251 cytology negative women were referred to one-year HPV retesting, 84.1% complied, and 55.5% were positive. Total colposcopy referral was 4.1%, and for cytology 1%. The detection rate for cervical intraepithelial neoplasia grade 2 or more severe was 10‰, compared with 3.7‰ using cytology. After three years, HPV-positivity was 3.4% (129/3831), overall colposcopy referral was 2.3% (most at one-year follow-up), and detection rate was 0.5/1000. Conclusions The first round detection rate was more than twice that of cytology screening, while colposcopy referral increased fourfold. At the second round, the detection rate decreased dramatically, showing that longer interval and more conservative protocols are needed.

  4. Prenatal and Perinatal Morbidity in Children with Tic Disorders: A Mainstream School-based Population Study in Central Spain.

    Science.gov (United States)

    Cubo, Esther; Hortigüela, Montesclaros; Jorge-Roldan, Sandra; Ciciliani, Selva Esther; Lopez, Patricia; Velasco, Leticia; Sastre, Emilio; Ausin, Vanesa; Delgado, Vanesa; Saez, Sara; Gabriel-Galán, José Trejo; Macarrón, Jesús

    2014-01-01

    While current research suggests that genetic factors confer the greatest risk for the development of tic disorders, studies of environmental factors are relatively few, with a lack of consistent risk factors across studies. Our aim is to analyze the association of tic disorders with exposure to prenatal and perinatal morbidity. This was a nested case-control study design. Cases and controls were selected and identified from a mainstream, school-based sample. The diagnosis of tic disorders was assigned by a movement disorder neurologist using 'Diagnostic and statistical manual of mental disorders, 4th edition, text revision' criteria, and neuropsychiatric comorbidities were screened using the Spanish computerized version of the Diagnostic Interview Schedule for Children Predictive Scale. Information regarding the exposure to pre-perinatal risk factors was collected by a retrospective review of the birth certificates. Logistic regression analyses were then performed to test the association of tic disorders with pre-perinatal risk factors. Out of 407 participants, complete pre-perinatal data were available in 153 children (64 with tics and 89 without tics). After adjusting for family history of tics, neonatal respiratory distress syndrome, body mass index, prenatal infection, and coexisting comorbid neuropsychiatric disturbances, tic disorders were associated with prenatal exposure to tobacco (odds ratio [OR] = 3.07, 95% confidence interval [CI] 1.24-7.60, p = 0.007), and cesarean section (OR = 5.78, 95% CI 1.60-20.91, p = 0.01). This nested case-control study of children with tic disorders demonstrates higher adjusted odds for tics in children with exposure to cesarean delivery and maternal smoking. Longitudinal, population-based samples are required to confirm these results.

  5. Biological restoration of central nervous system architecture and function: part 3-stem cell- and cell-based applications and realities in the biological management of central nervous system disorders: traumatic, vascular, and epilepsy disorders.

    Science.gov (United States)

    Farin, Azadeh; Liu, Charles Y; Langmoen, Iver A; Apuzzo, Michael L J

    2009-11-01

    STEM CELL THERAPY has emerged as a promising novel therapeutic endeavor for traumatic brain injury, spinal cord injury, stroke, and epilepsy in experimental studies. A few preliminary clinical trials have further supported its safety and early efficacy after transplantation into humans. Although not yet clinically available for central nervous system disorders, stem cell technology is expected to evolve into one of the most powerful tools in the biological management of complex central nervous system disorders, many of which currently have limited treatment modalities. The identification of stem cells, discovery of neurogenesis, and application of stem cells to treat central nervous system disorders represent a dramatic evolution and expansion of the neurosurgeon's capabilities into the neurorestoration and neuroregeneration realms. In Part 3 of a 5-part series on stem cells, we discuss the theory, experimental evidence, and clinical data pertaining to the use of stem cells for the treatment of traumatic, vascular, and epileptic disorders.

  6. The Fisher-information-based uncertainty relation, Cramer-Rao inequality and kinetic energy for the D-dimensional central problem

    Energy Technology Data Exchange (ETDEWEB)

    Dehesa, J S [Departamento de Fisica Atomica, Molecular y Nuclear, Universidad de Granada, 18071-Granada (Spain); Gonzalez-Ferez, R [Departamento de Fisica Atomica, Molecular y Nuclear, Universidad de Granada, 18071-Granada (Spain); Sanchez-Moreno, P [Departamento de Fisica Atomica, Molecular y Nuclear, Universidad de Granada, 18071-Granada (Spain)

    2007-02-23

    The inequality >= (l+1/2){sup 2}, with L being the grand orbital quantum number, and its conjugate relation for ((r{sup 2}) (p{sup -2})) are shown to be fulfilled in the D-dimensional central problem. Their use has allowed us to improve the Fisher-information-based uncertainty relation (I{sub {rho}}I{sub {gamma}}{>=} const) and the Cramer-Rao inequalities ((r{sup 2})I{sub {rho}} {>=} D{sup 2}; (p{sup 2})I{sub {gamma}} {>=} D{sup 2}). In addition, the kinetic energy and the radial expectation value (r{sup 2}) are shown to be bounded from below by the Fisher information in position and momentum spaces, denoted by I{sub {rho}} and I{sub {gamma}}, respectively.

  7. BioCichlid: central dogma-based 3D visualization system of time-course microarray data on a hierarchical biological network.

    Science.gov (United States)

    Ishiwata, Ryosuke R; Morioka, Masaki S; Ogishima, Soichi; Tanaka, Hiroshi

    2009-02-15

    BioCichlid is a 3D visualization system of time-course microarray data on molecular networks, aiming at interpretation of gene expression data by transcriptional relationships based on the central dogma with physical and genetic interactions. BioCichlid visualizes both physical (protein) and genetic (regulatory) network layers, and provides animation of time-course gene expression data on the genetic network layer. Transcriptional regulations are represented to bridge the physical network (transcription factors) and genetic network (regulated genes) layers, thus integrating promoter analysis into the pathway mapping. BioCichlid enhances the interpretation of microarray data and allows for revealing the underlying mechanisms causing differential gene expressions. BioCichlid is freely available and can be accessed at http://newton.tmd.ac.jp/. Source codes for both biocichlid server and client are also available.

  8. Risk mapping of Rinderpest sero-prevalence in Central and Southern Somalia based on spatial and network risk factors.

    Science.gov (United States)

    Ortiz-Pelaez, Angel; Pfeiffer, Dirk U; Tempia, Stefano; Otieno, F Tom; Aden, Hussein H; Costagli, Riccardo

    2010-04-28

    In contrast to most pastoral systems, the Somali livestock production system is oriented towards domestic trade and export with seasonal movement patterns of herds/flocks in search of water and pasture and towards export points. Data from a rinderpest survey and other data sources have been integrated to explore the topology of a contact network of cattle herds based on a spatial proximity criterion and other attributes related to cattle herd dynamics. The objective of the study is to integrate spatial mobility and other attributes with GIS and network approaches in order to develop a predictive spatial model of presence of rinderpest. A spatial logistic regression model was fitted using data for 562 point locations. It includes three statistically significant continuous-scale variables that increase the risk of rinderpest: home range radius, herd density and clustering coefficient of the node of the network whose link was established if the sum of the home ranges of every pair of nodes was equal or greater than the shortest distance between the points. The sensitivity of the model is 85.1% and the specificity 84.6%, correctly classifying 84.7% of the observations. The spatial autocorrelation not accounted for by the model is negligible and visual assessment of a semivariogram of the residuals indicated that there was no undue amount of spatial autocorrelation. The predictive model was applied to a set of 6176 point locations covering the study area. Areas at high risk of having serological evidence of rinderpest are located mainly in the coastal districts of Lower and Middle Juba, the coastal area of Lower Shabele and in the regions of Middle Shabele and Bay. There are also isolated spots of high risk along the border with Kenya and the southern area of the border with Ethiopia. The identification of point locations and areas with high risk of presence of rinderpest and their spatial visualization as a risk map will be useful for informing the prioritization of

  9. Scientific Discoveries in the Central Arctic Ocean Based on Seafloor Mapping Carried out to Support Article 76 Extended Continental Shelf Claims (Invited)

    Science.gov (United States)

    Jakobsson, M.; Mayer, L. A.; Marcussen, C.

    2013-12-01

    Despite the last decades of diminishing sea-ice cover in the Arctic Ocean, ship operations are only possible in vast sectors of the central Arctic using the most capable polar-class icebreakers. There are less than a handful of these icebreakers outfitted with modern seafloor mapping equipment. This implies either fierce competition between those having an interest in using these icebreakers for investigations of the shape and properties of Arctic Ocean seafloor or, preferably, collaboration. In this presentation examples will be shown of scientific discoveries based on mapping data collected during Arctic Ocean icebreaker expeditions carried out for the purpose of substantiating claims for an extended continental shelf under United Nations Convention of the Law of the Sea (UNCLOS) Article 76. Scientific results will be presented from the suite of Lomonosov Ridge off Greenland (LOMROG) expeditions (2007, 2009, and 2012), shedding new light on Arctic Ocean oceanography and glacial history. The Swedish icebreaker Oden was used in collaboration between Sweden and Denmark during LOMROG to map and sample portions of the central Arctic Ocean; specifically focused on the Lomonosov Ridge north of Greenland. While the main objective of the Danish participation was seafloor and sub-seabed mapping to substantiate their Article 76 claim, LOMROG also included several scientific components, with scientists from both countries involved. Other examples to be presented are based on data collected using US Coast Guard Cutter Healy, which for several years has carried out mapping in the western Arctic Ocean for the US continental shelf program. All bathymetric data collected with Oden and Healy have been contributed to the International Bathymetric Chart of the Arctic Ocean (IBCAO). This is also the case for bathymetric data collected by Canadian Coast Guard Ship Louis S. St-Laurent for Canada's extended continental shelf claim. Together, the bathymetric data collected during these

  10. Groundwater management based on monitoring of land subsidence and groundwater levels in the Kanto Groundwater Basin, Central Japan

    Science.gov (United States)

    Furuno, K.; Kagawa, A.; Kazaoka, O.; Kusuda, T.; Nirei, H.

    2015-11-01

    Over 40 million people live on and exploit the groundwater resources of the Kanto Plain. The Plain encompasses metropolitan Tokyo and much of Chiba Prefecture. Useable groundwater extends to the base of the Kanto Plain, some 2500 to 3000 m below sea level. Much of the Kanto Plain surface is at sea level. By the early 1970s, with increasing urbanization and industrial expansion, local overdraft of groundwater resources caused major ground subsidence and damage to commercial and residential structures as well as to local and regional infrastructure. Parts of the lowlands around Tokyo subsided to 4.0 m below sea level; particularly affected were the suburbs of Funabashi and Gyotoku in western Chiba. In the southern Kanto Plain, regulations, mainly by local government and later by regional agencies, led to installation of about 500 monitoring wells and almost 5000 bench marks by the 1990's. Many of them are still working with new monitoring system. Long-term monitoring is important. The monitoring systems are costly, but the resulting data provide continuous measurement of the "health" of the Kanto Groundwater Basin, and thus permit sustainable use of the groundwater resource.

  11. Communication and transportation as quality of life determinants based on cities in Central Java Province and Special Region of Yogyakarta

    Science.gov (United States)

    Subanti, S.; Hartatik; Hakim, A. R.; Daerobi, A.; Setiawan, R. R.

    2018-03-01

    The quality of life become a concern for individuals and communities seeking to find their sustainable life. Some people in industry, consumer groups, academics, and policy makers have sought to better understand how communication and transportation contributes on quality of life. Thus, this paper aimed to calculate quality of life based on transportation and communication. Indicator of transportation such as road surface condition and the availability of public of transportation; while indicator of communication such as the availability of television signal, post services, cable phone, and internet cafes. Cities involved in this study were Magelang, Surakarta, Salatiga, Semarang, Pekalongan, Tegal,and Yogyakarta. This paper used national socio-economic survey data and the potential of village data. Estimation techniques using multiple regression method. The findings of this paper, (1) transportation and communication were linked to Quality of Life; (2) the highest quality of life obtained by the city of Magelang, while the lowest was occupied by the City of Pekalongan. Suggestion from this paper, local government should have to prioritize infrastructure development such as transportation and communication because it can improve the quality of life whose lived in the city.

  12. Annotated genetic linkage maps of Pinus pinaster Ait. from a Central Spain population using microsatellite and gene based markers.

    Science.gov (United States)

    de Miguel, Marina; de Maria, Nuria; Guevara, M Angeles; Diaz, Luis; Sáez-Laguna, Enrique; Sánchez-Gómez, David; Chancerel, Emilie; Aranda, Ismael; Collada, Carmen; Plomion, Christophe; Cabezas, José-Antonio; Cervera, María-Teresa

    2012-10-04

    Pinus pinaster Ait. is a major resin producing species in Spain. Genetic linkage mapping can facilitate marker-assisted selection (MAS) through the identification of Quantitative Trait Loci and selection of allelic variants of interest in breeding populations. In this study, we report annotated genetic linkage maps for two individuals (C14 and C15) belonging to a breeding program aiming to increase resin production. We use different types of DNA markers, including last-generation molecular markers. We obtained 13 and 14 linkage groups for C14 and C15 maps, respectively. A total of 211 and 215 markers were positioned on each map and estimated genome length was between 1,870 and 2,166 cM respectively, which represents near 65% of genome coverage. Comparative mapping with previously developed genetic linkage maps for P. pinaster based on about 60 common markers enabled aligning linkage groups to this reference map. The comparison of our annotated linkage maps and linkage maps reporting QTL information revealed 11 annotated SNPs in candidate genes that co-localized with previously reported QTLs for wood properties and water use efficiency. This study provides genetic linkage maps from a Spanish population that shows high levels of genetic divergence with French populations from which segregating progenies have been previously mapped. These genetic maps will be of interest to construct a reliable consensus linkage map for the species. The importance of developing functional genetic linkage maps is highlighted, especially when working with breeding populations for its future application in MAS for traits of interest.

  13. Annotated genetic linkage maps of Pinus pinaster Ait. from a Central Spain population using microsatellite and gene based markers

    Directory of Open Access Journals (Sweden)

    de Miguel Marina

    2012-10-01

    Full Text Available Abstract Background Pinus pinaster Ait. is a major resin producing species in Spain. Genetic linkage mapping can facilitate marker-assisted selection (MAS through the identification of Quantitative Trait Loci and selection of allelic variants of interest in breeding populations. In this study, we report annotated genetic linkage maps for two individuals (C14 and C15 belonging to a breeding program aiming to increase resin production. We use different types of DNA markers, including last-generation molecular markers. Results We obtained 13 and 14 linkage groups for C14 and C15 maps, respectively. A total of 211 and 215 markers were positioned on each map and estimated genome length was between 1,870 and 2,166 cM respectively, which represents near 65% of genome coverage. Comparative mapping with previously developed genetic linkage maps for P. pinaster based on about 60 common markers enabled aligning linkage groups to this reference map. The comparison of our annotated linkage maps and linkage maps reporting QTL information revealed 11 annotated SNPs in candidate genes that co-localized with previously reported QTLs for wood properties and water use efficiency. Conclusions This study provides genetic linkage maps from a Spanish population that shows high levels of genetic divergence with French populations from which segregating progenies have been previously mapped. These genetic maps will be of interest to construct a reliable consensus linkage map for the species. The importance of developing functional genetic linkage maps is highlighted, especially when working with breeding populations for its future application in MAS for traits of interest.

  14. USARCENT AOR Contingency Base Waste Stream Analysis: An Analysis of Solid Waste Streams at Five Bases in the U. S. Army Central (USARCENT) Area of Responsibility

    Science.gov (United States)

    2013-03-31

    and Plastics Waste in As Bench Scale Combustor. University of Technology, Malaysia . http://eprints.utm.my/2854/1/75186.pdf. ASTM – ASTM...prevalent types of solid waste are food (19.1% by average sample weight), wood (18.9%), and plastics (16.0%) based on analysis of bases in...within the interval shown. Food and wood wastes are the largest components of the average waste stream (both at ~19% by weight), followed by plastic

  15. Centrally Banked Cryptocurrencies

    OpenAIRE

    Danezis, George; Meiklejohn, Sarah

    2015-01-01

    Current cryptocurrencies, starting with Bitcoin, build a decentralized blockchain-based transaction ledger, maintained through proofs-of-work that also generate a monetary supply. Such decentralization has benefits, such as independence from national political control, but also significant limitations in terms of scalability and computational cost. We introduce RSCoin, a cryptocurrency framework in which central banks maintain complete control over the monetary supply, but rely on a distribut...

  16. Centrally Banked Cryptocurrencies

    OpenAIRE

    Danezis, G.; Meiklejohn, S.

    2016-01-01

    Current cryptocurrencies, starting with Bitcoin, build a decentralized blockchain-based transaction ledger, maintained through proofs-of-work that also serve to generate a monetary supply. Such decentralization has benefits, such as independence from national political control, but also significant limitations in terms of computational costs and scalability. We introduce RSCoin, a cryptocurrency framework in which central banks maintain complete control over the monetary supply, but rely on...

  17. The Central Trigger Processor (CTP)

    CERN Multimedia

    Franchini, Matteo

    2016-01-01

    The Central Trigger Processor (CTP) receives trigger information from the calorimeter and muon trigger processors, as well as from other sources of trigger. It makes the Level-1 decision (L1A) based on a trigger menu.

  18. Long-Lasting Insecticidal Hammocks for controlling forest malaria: a community-based trial in a rural area of central Vietnam.

    Directory of Open Access Journals (Sweden)

    Ngo Duc Thang

    2009-10-01

    Full Text Available In Vietnam, malaria remains a problem in some remote areas located along its international borders and in the central highlands, partly due to the bionomics of the local vector, mainly found in forested areas and less vulnerable to standard control measures. Long Lasting Insecticidal Hammocks (LLIH, a tailored and user-friendly tool for forest workers, may further contribute in reducing the malaria burden. Their effectiveness was tested in a large community-based intervention trial carried out in Ninh Thuan province in Central Vietnam.Thirty villages (population 18,646 were assembled in 20 clusters (1,000 individuals per cluster that were randomly allocated to either the intervention or control group (no LLIH after stratification according to the pre-intervention P. falciparum antibody prevalence ( or =30%. LLIH were distributed to the intervention group in December 2004. For the following 2 years, the incidence of clinical malaria and the prevalence of infection were determined by passive case detection at community level and by bi-annual malariometric surveys. A 2-fold larger effect on malaria incidence in the intervention as compared to the control group was observed. Similarly, malaria prevalence decreased more substantially in the intervention (1.6-fold greater reduction than in the control group. Both for incidence and prevalence, a stronger and earlier effect of the intervention was observed in the high endemicity stratum. The number of malaria cases and infections averted by the intervention overall was estimated at 10.5 per 1,000 persons and 5.6/100 individuals, respectively, for the last half of 2006. In the high endemicity stratum, the impact was much higher, i.e. 29/1000 malaria cases and 15.7 infections/100 individuals averted.LLIH reduced malaria incidence and prevalence in this remote and forested area of Central Vietnam. As the targets of the newly-launched Global Malaria Action Plan include the 75% reduction of the global

  19. Is violence associated with increased risk behavior among MSM? Evidence from a population-based survey conducted across nine cities in Central America.

    Science.gov (United States)

    Wheeler, Jennifer; Anfinson, Katherine; Valvert, Dennis; Lungo, Susana

    2014-01-01

    There is a dearth of research examining the linkages between violence and HIV risk behavior among men who have sex with men (MSM), including those who identify as transgender women (TW), particularly in Central America where violence is widespread. In this paper, we use population-based survey results to independently examine the correlations between physical, emotional and sexual violence and HIV risk behavior among MSM populations in five countries in Central America. As part of USAID's Combination Prevention for HIV program in Central America, PASMO conducted population based surveys using respondent-driven sampling (RDS) in nine cities in Guatemala, El Salvador, Nicaragua, Costa Rica, and Panama. Initial seeds were recruited using the following criteria: individuals who represented subgroups of MSM by self-identification (homosexual vs. heterosexual or bisexual vs. transgender), social economic strata, and by sex work practices. This study examines the association between violence and 1) HIV risk behaviors relevant to the study populations; 2) protective behaviors; and 3) reported STIs. Individualized RDS estimator weights for each outcome variable were calculated using RDSAT software, and logistic regression analysis was used to determine associations between different forms of violence and the outcome variables. MSM who experienced physical violence were more likely to be engaged in transactional sex (OR: 1.76 [1.42-2.18]), have multiple partners in the past 30 days (OR: 1.37 [1.09-1.71]), and have engaged in sex under the influence of alcohol or drugs (OR: 1.51 [1.24-1.83]). Both physical violence and psychological/verbal violence were also associated with reporting STI symptoms or diagnosis within the past 12 months (OR: 1.72 [1.34-2.21] and 1.80 [1.45-2.23]). The effects of violence on the outcomes were observed after controlling for other risk factors. Transgender women were 3.9 times more likely to report engaging in transactional sex. Respondents who

  20. Is violence associated with increased risk behavior among MSM? Evidence from a population-based survey conducted across nine cities in Central America

    Directory of Open Access Journals (Sweden)

    Jennifer Wheeler

    2014-10-01

    Full Text Available Background/Objective: There is a dearth of research examining the linkages between violence and HIV risk behavior among men who have sex with men (MSM, including those who identify as transgender women (TW, particularly in Central America where violence is widespread. In this paper, we use population-based survey results to independently examine the correlations between physical, emotional and sexual violence and HIV risk behavior among MSM populations in five countries in Central America. Design: As part of USAID's Combination Prevention for HIV program in Central America, PASMO conducted population based surveys using respondent-driven sampling (RDS in nine cities in Guatemala, El Salvador, Nicaragua, Costa Rica, and Panama. Initial seeds were recruited using the following criteria: individuals who represented subgroups of MSM by self-identification (homosexual vs. heterosexual or bisexual vs. transgender, social economic strata, and by sex work practices. This study examines the association between violence and 1 HIV risk behaviors relevant to the study populations; 2 protective behaviors; and 3 reported STIs. Individualized RDS estimator weights for each outcome variable were calculated using RDSAT software, and logistic regression analysis was used to determine associations between different forms of violence and the outcome variables. Results: MSM who experienced physical violence were more likely to be engaged in transactional sex (OR: 1.76 [1.42–2.18], have multiple partners in the past 30 days (OR: 1.37 [1.09–1.71], and have engaged in sex under the influence of alcohol or drugs (OR: 1.51 [1.24–1.83]. Both physical violence and psychological/verbal violence were also associated with reporting STI symptoms or diagnosis within the past 12 months (OR: 1.72 [1.34–2.21] and 1.80 [1.45–2.23]. The effects of violence on the outcomes were observed after controlling for other risk factors. Transgender women were 3.9 times more likely

  1. Centralized digital control of accelerators

    International Nuclear Information System (INIS)

    Melen, R.E.

    1983-09-01

    In contrasting the title of this paper with a second paper to be presented at this conference entitled Distributed Digital Control of Accelerators, a potential reader might be led to believe that this paper will focus on systems whose computing intelligence is centered in one or more computers in a centralized location. Instead, this paper will describe the architectural evolution of SLAC's computer based accelerator control systems with respect to the distribution of their intelligence. However, the use of the word centralized in the title is appropriate because these systems are based on the use of centralized large and computationally powerful processors that are typically supported by networks of smaller distributed processors

  2. Current situation regarding central venous port implantation procedures and complications: a questionnaire-based survey of 11,693 implantations in Japan.

    Science.gov (United States)

    Shiono, Masatoshi; Takahashi, Shin; Takahashi, Masanobu; Yamaguchi, Takuhiro; Ishioka, Chikashi

    2016-12-01

    We conducted a nationwide questionnaire-based survey to understand the current situation regarding central venous port implantation in order to identify the ideal procedure. Questionnaire sheets concerning the number of implantation procedures and the incidence of complications for all procedures completed in 2012 were sent to 397 nationwide designated cancer care hospitals in Japan in June 2013. Venipuncture sites were categorized as chest, neck, upper arm, forearm, and others. Methods were categorized as landmark, cut-down, ultrasound-mark, real-time ultrasound guided, venography, and other groups. We received 374 responses (11,693 procedures) from 153 centers (38.5 %). The overall complication rates were 7.4 % for the chest (598/8,097 cases); 6.8 % for the neck (157/2325); 5.2 % for the upper arm (54/1,033); 7.3 % for the forearm (9/124); and 6.1 % for the other groups (7/114). Compared to the chest group, only the upper arm group showed a significantly lower incidence of complications (P = 0.010), and multivariate logistic regression (odds ratio 0.69; 95 % confidence interval 0.51-0.91; P = 0.008) also showed similar findings. Real-time ultrasound-guided puncture was most commonly used in the upper arm group (83.8 %), followed by the neck (69.8 %), forearm (53.2 %), chest (41.8 %), and other groups (34.2 %). Upper arm venipuncture with ultrasound guidance seems the most promising technique to prevent complications of central venous port implantation.

  3. A revised design approach of the attachment system for the ITER EU-HCPB-TBM based on a central cylindrical connection element

    International Nuclear Information System (INIS)

    Zeile, Christian; Neuberger, Heiko

    2012-01-01

    Highlights: ► Design of an attachment system based on a cylinder to connect TBM and shield. ► Attachment system has to cope with high EM loads and different thermal expansions. ► Stiff design and central position fulfill these requirements. ► Transient thermal-structural analyses confirm compliance of design with design codes. - Abstract: The EU-Helium Cooled Pebble Bed Test Blanket Module (HCPB-TBM), which is located inside an equatorial port plug, is attached to the shield by an attachment system. The design of the attachment system has to fulfill two conflicting requirements. On the one hand, it has to transfer the high electromagnetic forces acting on the TBM to the shield and on the other hand, it has to compensate the different thermal expansions between the shield and the back plate of the TBM. The recent design approach of the attachment system consists of a hollow cylinder located at the center of the back plate. This design combines two advantages: a simple geometry and correspondingly low fabrication effort and the central location where the differential strain between back plate and shield is minimal. Static and transient thermal-structural analyses of the most demanding load cases, a fast vertical displacement event type II and the operation state tritium outgassing, have been performed to evaluate the design and confirm the compliance with the relevant design codes. A welded connection of the attachment system to the TBM back plate and a bolted connection in combination with a splined shaft is proposed for the shield side because of the dissimilar materials.

  4. The Last Interglacial-Glacial cycle (MIS 5-2) re-examined based on long proxy records from central and northern Europe

    Science.gov (United States)

    Helmens, Karin F.

    2014-02-01

    Current multi-proxy studies on a long sediment sequence preserved at Sokli (N Finland), i.e. in the central area of Fennoscandian glaciations, are drastically changing classic ideas of glaciations, vegetation and climate in northern Europe during the Late Pleistocene. The sediments in the Sokli basin have escaped major glacial erosion due to non-typical bedrock conditions. In this review, the Sokli record is compared in great detail with other long proxy records from central, temperate and northern, boreal Europe. These comprise the classic records of La Grande Pile (E France) and Oerel (N Germany) and more recently obtained records from Horoszki Duże (E Poland) and Lake Yamozero (NW Russia). The focus of the review is on pollen, lithology and macrofossil- and insect-based temperature inferences. The long records are further compared with recent proxy data from nearby terrestrial sites as well as with the rapidly accumulating high-resolution proxy data from the ocean realm. The comparison allows a re-examination of the environmental history and climate evolution of the Last Interglacial-Glacial (LI-G) cycle (MIS 5-2). It shows that environmental and climate conditions during MIS 5 (ca 130-70 ka BP) were distinctly different from those during MIS 4-2 (ca 70-15 ka BP). MIS 5 is characterized by three long forested intervals (broadly corresponding to MIS 5e, 5c, 5a), both in temperate and northern boreal Europe. These mild periods were interrupted by two short, relatively cold and dry intervals (MIS 5d and 5b) with mountain-centered glaciation in Fennoscandia. Millennial scale climate events were superimposed upon these longer lasting climate fluctuations. The time interval encompassing MIS 4-2 shows open vegetation. It is characterized by two glacial maxima (MIS 4 and 2) with sub-continental scale glaciation over northern Europe and dry conditions in strongly continental eastern European settings. High amplitude climate oscillations of millennial duration

  5. In the pursuit of a semantic similarity metric based on UMLS annotations for articles in PubMed Central Open Access.

    Science.gov (United States)

    Garcia Castro, Leyla Jael; Berlanga, Rafael; Garcia, Alexander

    2015-10-01

    Although full-text articles are provided by the publishers in electronic formats, it remains a challenge to find related work beyond the title and abstract context. Identifying related articles based on their abstract is indeed a good starting point; this process is straightforward and does not consume as many resources as full-text based similarity would require. However, further analyses may require in-depth understanding of the full content. Two articles with highly related abstracts can be substantially different regarding the full content. How similarity differs when considering title-and-abstract versus full-text and which semantic similarity metric provides better results when dealing with full-text articles are the main issues addressed in this manuscript. We have benchmarked three similarity metrics - BM25, PMRA, and Cosine, in order to determine which one performs best when using concept-based annotations on full-text documents. We also evaluated variations in similarity values based on title-and-abstract against those relying on full-text. Our test dataset comprises the Genomics track article collection from the 2005 Text Retrieval Conference. Initially, we used an entity recognition software to semantically annotate titles and abstracts as well as full-text with concepts defined in the Unified Medical Language System (UMLS®). For each article, we created a document profile, i.e., a set of identified concepts, term frequency, and inverse document frequency; we then applied various similarity metrics to those document profiles. We considered correlation, precision, recall, and F1 in order to determine which similarity metric performs best with concept-based annotations. For those full-text articles available in PubMed Central Open Access (PMC-OA), we also performed dispersion analyses in order to understand how similarity varies when considering full-text articles. We have found that the PubMed Related Articles similarity metric is the most suitable for

  6. Application of fractal modeling and PCA method for hydrothermal alteration mapping in the Saveh area (Central Iran based on ASTER multispectral data

    Directory of Open Access Journals (Sweden)

    Mirko Ahmadfaraj

    2016-06-01

    Full Text Available The aim of this study is determination and separation of alteration zones using Concentration-Area (C-A fractal model based on remote sensing data which has been extracted from Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER images. The studied area is on the SW part of Saveh, 1:250,000 geological map, which is located in Urumieh-Dokhtar magmatic belt, Central Iran. The pixel values were computed by Principal Component Analysis (PCA method used to determine phyllic, argillic, and propylitic alteration zones. The C-A fractal model is utilized for separation of different parts of alteration zones due to their intensity. The log-log C-A plots reveal multifractal nature for phyllic, argillic, and propylitic alteration zones. The obtained results based on fractal model show that the main trend of the alteration zones is in NW-SE direction. Compared to the geological map of the study area and copper mineralizations, the alteration zones have been detected properly and correlate with the mineral occurrences, intrusive rock, and faults.

  7. Creole Hens and Ranga-Ranga: Campesino Foodways and Biocultural Resource-Based Development in the Central Valley of Tarija, Bolivia

    Directory of Open Access Journals (Sweden)

    Katherine L. Turner

    2016-08-01

    Full Text Available Biocultural heritage-based products, including regional specialty foods, are increasingly part of sustainable rural development strategies. While export-oriented biocultural products are often the most visible, we examine the role of campesino gastronomic heritage in the Central Valley of Tarija, Bolivia, as a case study of a local market-centered biocultural resource-based development strategy reflected in an alternative agri-food network. We develop a biocultural sustainability framework to examine this network from ecological, economic and sociocultural perspectives. Data are drawn from interviews (n = 77, surveys (n = 89 and participant observation, with primary and secondary producers of traditional and new products, as well as restaurant owners, market vendors and local consumers. We find that campesino biocultural heritage and the alternative agri-food network surrounding it represent an influential territorial project that underpins many household economies, particularly for women. We conclude that the relatively small investments by local governments to promote campesino gastronomic heritage are having positive ripple effects on small-scale producer livelihoods and on biocultural sustainability. We suggest that further support to increase market access and reduce other barriers to participation in alternative food networks will likely increase the options and benefits available to small-scale producers mobilising campesino gastronomic heritage within the local economy.

  8. Simulation-based medical education training improves short and long-term competency in, and knowledge of central venous catheter insertion: A before and after intervention study.

    Science.gov (United States)

    Cartier, Vanessa; Inan, Cigdem; Zingg, Walter; Delhumeau, Cecile; Walder, Bernard; Savoldelli, Georges L

    2016-08-01

    Multimodal educational interventions have been shown to improve short-term competency in, and knowledge of central venous catheter (CVC) insertion. To evaluate the effectiveness of simulation-based medical education training in improving short and long-term competency in, and knowledge of CVC insertion. Before and after intervention study. University Geneva Hospital, Geneva, Switzerland, between May 2008 and January 2012. Residents in anaesthesiology aware of the Seldinger technique for vascular puncture. Participants attended a half-day course on CVC insertion. Learning objectives included work organization, aseptic technique and prevention of CVC complications. CVC insertion competency was tested pretraining, posttraining and then more than 2 years after training (sustainability phase). The primary study outcome was competency as measured by a global rating scale of technical skills, a hand hygiene compliance score and a checklist compliance score. Secondary outcome was knowledge as measured by a standardised pretraining and posttraining multiple-choice questionnaire. Statistical analyses were performed using paired Student's t test or Wilcoxon signed-rank test. Thirty-seven residents were included; 18 were tested in the sustainability phase (on average 34 months after training). The average global rating of skills was 23.4 points (±SD 4.08) before training, 32.2 (±4.51) after training (P Simulation-based medical education training was effective in improving short and long-term competency in, and knowledge of CVC insertion.

  9. Distribution of lithostratigraphic units within the central block of Yucca Mountain, Nevada: A three-dimensional computer-based model, Version YMP.R2.0

    International Nuclear Information System (INIS)

    Buesch, D.C.; Nelson, J.E.; Dickerson, R.P.; Drake, R.M. II; San Juan, C.A.; Spengler, R.W.; Geslin, J.K.; Moyer, T.C.

    1996-01-01

    Yucca Mountain, Nevada is underlain by 14.0 to 11.6 Ma volcanic rocks tilted eastward 3 degree to 20 degree and cut by faults that were primarily active between 12.7 and 11.6 Ma. A three-dimensional computer-based model of the central block of the mountain consists of seven structural subblocks composed of six formations and the interstratified-bedded tuffaceous deposits. Rocks from the 12.7 Ma Tiva Canyon Tuff, which forms most of the exposed rocks on the mountain, to the 13.1 Ma Prow Pass Tuff are modeled with 13 surfaces. Modeled units represent single formations such as the Pah Canyon Tuff, grouped units such as the combination of the Yucca Mountain Tuff with the superjacent bedded tuff, and divisions of the Topopah Spring Tuff such as the crystal-poor vitrophyre interval. The model is based on data from 75 boreholes from which a structure contour map at the base of the Tiva Canyon Tuff and isochore maps for each unit are constructed to serve as primary input. Modeling consists of an iterative cycle that begins with the primary structure-contour map from which isochore values of the subjacent model unit are subtracted to produce the structure contour map on the base of the unit. This new structure contour map forms the input for another cycle of isochore subtraction to produce the next structure contour map. In this method of solids modeling, the model units are presented by surfaces (structure contour maps), and all surfaces are stored in the model. Surfaces can be converted to form volumes of model units with additional effort. This lithostratigraphic and structural model can be used for (1) storing data from, and planning future, site characterization activities, (2) preliminary geometry of units for design of Exploratory Studies Facility and potential repository, and (3) performance assessment evaluations

  10. Canyon incision chronology based on ignimbrite stratigraphy and cut-and-fill sediment sequences in SW Peru documents intermittent uplift of the western Central Andes

    Science.gov (United States)

    Thouret, Jean-Claude; Gunnell, Yanni; Jicha, Brian R.; Paquette, Jean-Louis; Braucher, Régis

    2017-12-01

    Based on an 40Ar/39Ar- and U/Pb-based chronostratigraphy of ignimbrite sheets and the geomorphological features of watersheds, river profiles and slope deposits in the Ocoña-Cotahuasi-Marán (OCM) and Colca valleys of southwest Peru, we reconstruct the valley incision history of the western Central Andes over the last c. 25 Myr. We further document the Pleistocene and Holocene evolution of deep valleys on the basis of 14 10Be surface-exposure ages obtained on debris-avalanche deposits and river straths. The data suggest that uplift was gradual over the past 25 Myr, but accelerated after c. 9 Ma. Valley incision started around 11-9 Ma and accelerated between 5 and 4 Ma. Incision was followed by several pulses of valley cut-and-fill after 2.3 Ma. Evidence presented suggest that the post-5 Ma sequence of accelerated canyon incision probably resulted from a combination of drainage piracy from the Cordilleran drainage divide towards the Altiplano, accentuated flexural tilting of the Western Cordillera towards the SE, and increased rainfall on the Altiplano after late Miocene uplift of the Eastern Cordillera. The valley deepening and slope steepening driven by tectonic uplift gave rise to large occurrences of rockslope failure. The collapsed rock masses periodically obstructed the canyons, thus causing abrupt changes in local base levels and interfering with the steadiness of fluvial incision. As a result, channel aggradation has prevailed in the lower-gradient, U-shaped Pacific-rim canyons, whereas re-incision through landslide deposits has occurred more rapidly across the steeper V-shaped, upper valleys. Existing canyon knickpoints are currently arrested at the boundary between the plutonic bedrock and widespread outcrops of middle Miocene ignimbritic caprock, where groundwater sapping favouring rock collapse may be the dominant process driving headward erosion.

  11. A Geochemical Mass-Balance Method for Base-Flow Separation, Upper Hillsborough River Watershed, West-Central Florida, 2003-2005 and 2009

    Science.gov (United States)

    Kish, G.R.; Stringer, C.E.; Stewart, M.T.; Rains, M.C.; Torres, A.E.

    2010-01-01

    Geochemical mass-balance (GMB) and conductivity mass-balance (CMB) methods for hydrograph separation were used to determine the contribution of base flow to total stormflow at two sites in the upper Hillsborough River watershed in west-central Florida from 2003-2005 and at one site in 2009. The chemical and isotopic composition of streamflow and precipitation was measured during selected local and frontal low- and high-intensity storm events and compared to the geochemical and isotopic composition of groundwater. Input for the GMB method included cation, anion, and stable isotope concentrations of surface water and groundwater, whereas input for the CMB method included continuous or point-sample measurement of specific conductance. The surface water is a calcium-bicarbonate type water, which closely resembles groundwater geochemically, indicating that much of the surface water in the upper Hillsborough River basin is derived from local groundwater discharge. This discharge into the Hillsborough River at State Road 39 and at Hillsborough River State Park becomes diluted by precipitation and runoff during the wet season, but retains the calcium-bicarbonate characteristics of Upper Floridan aquifer water. Field conditions limited the application of the GMB method to low-intensity storms but the CMB method was applied to both low-intensity and high-intensity storms. The average contribution of base flow to total discharge for all storms ranged from 31 to 100 percent, whereas the contribution of base flow to total discharge during peak discharge periods ranged from less than 10 percent to 100 percent. Although calcium, magnesium, and silica were consistent markers of Upper Floridan aquifer chemistry, their use in calculating base flow by the GMB method was limited because the frequency of point data collected in this study was not sufficient to capture the complete hydrograph from pre-event base-flow to post-event base-flow concentrations. In this study, pre-event water

  12. Does central bank communication really lead to better forecasts of policy decisions? New evidence based on a Taylor rule model for the ECB

    NARCIS (Netherlands)

    Sturm, Jan-Egbert; De Haan, Jakob

    Nowadays, it is widely believed that greater disclosure and clarity over policy may lead to greater predictability of central bank actions. We examine whether communication by the European Central Bank (ECB) adds information compared to the information provided by a Taylor rule model in which

  13. Central Nervous System Vasculitis

    Science.gov (United States)

    ... of Vasculitis / Central Nervous System (CNS) Vasculitis Central Nervous System (CNS) Vasculitis Swap out your current Facebook Profile ... Facebook personal page. Replace with this image. Central nervous system (CNS) vasculitis is inflammation of blood vessel walls ...

  14. Turbine model for the Laguna Verde nucleo electric central based in the RELAP code; Modelo de turbina para la Central nucleoelectrica de Laguna Verde basado en el codigo RELAP

    Energy Technology Data Exchange (ETDEWEB)

    Cortes M, F.S.; Ramos P, J.C.; Salazar S, E.; Chavez M, C. [Facultad de Ingenieria, Division de Estudios de Posgrado, Grupo de Ingenieria Nuclear, UNAM (Mexico)]. e-mail: cchavez2@cableonline.com.mx

    2003-07-01

    The Nuclear Power stations as Laguna Verde occupy at the present time a place every time but important as non pollutant alternative, economic and trusty to generate electricity. It is for it that the Group of Nuclear Engineering of the Engineering Faculty (GrlNFI) of the National Autonomous University of Mexico (UNAM) it develops investigation projects applied to Nuclear Centrals. One of the projects in process is the development of a Classroom simulator, which it can configures to consent to diverse models of nuclear systems with training purposes in normal operation, or, to consent to specialized nuclear codes for the analysis of transitory events and have a severe accident. This work describes the development, implementation and it proves of a simplified model of the Main turbine to be integrated to the group of models of the Classroom simulator. It is part of the current effort of GrlNFI guided to obtain a representation of all the dynamic models necessary to simulate the Plant Balance of the Laguna Verde Central. It is included the development of the unfolding graphic which represent the modeling of the Main turbine, and of the control interface that allows the user to manipulate in simple way, direct and interactive this device during the training or the analysis. With this work it is wanted to contribute to the training of new technicians and to support the operation personnel of the Centrals. Also, the developed infrastructure is guided to contribute in the design and analysis of new Nuclear Power stations with the contribution of new computational tools for the visualization, simulation and process control. (Author)

  15. Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates

    Energy Technology Data Exchange (ETDEWEB)

    Mandal, Mihirbaran; Wu, Yusheng; Misiaszek, Jeffrey; Li, Guoqing; Buevich, Alexei; Caldwell, John P.; Liu, Xiaoxiang; Mazzola, Robert D.; Orth, Peter; Strickland, Corey; Voigt, Johannes; Wang, Hongwu; Zhu, Zhaoning; Chen, Xia; Grzelak, Michael; Hyde, Lynn A.; Kuvelkar, Reshma; Leach, Prescott T.; Terracina, Giuseppe; Zhang, Lili; Zhang, Qi; Michener, Maria S.; Smith, Brad; Cox, Kathleen; Grotz, Diane; Favreau, Leonard; Mitra, Kaushik; Kazakevich, Irina; McKittrick, Brian A.; Greenlee, William; Kennedy, Matthew E.; Parker, Eric M.; Cumming, Jared N.; Stamford, Andrew W. (Merck)

    2016-04-14

    We describe successful efforts to optimize the in vivo profile and address off-target liabilities of a series of BACE1 inhibitors represented by 6 that embodies the recently validated fused pyrrolidine iminopyrimidinone scaffold. Employing structure-based design, truncation of the cyanophenyl group of 6 that binds in the S3 pocket of BACE1 followed by modification of the thienyl group in S1 was pursued. Optimization of the pyrimidine substituent that binds in the S2'–S2'' pocket of BACE1 remediated time-dependent CYP3A4 inhibition of earlier analogues in this series and imparted high BACE1 affinity. These efforts resulted in the discovery of difluorophenyl analogue 9 (MBi-4), which robustly lowered CSF and cortex Aβ40 in both rats and cynomolgus monkeys following a single oral dose. Compound 9 represents a unique molecular shape among BACE inhibitors reported to potently lower central Aβ in nonrodent preclinical species.

  16. Bioactive Potential of Marine Macroalgae from the Central Red Sea (Saudi Arabia) Assessed by High-Throughput Imaging-Based Phenotypic Profiling

    KAUST Repository

    Kremb, Stephan Georg

    2017-03-20

    Marine algae represent an important source of novel natural products. While their bioactive potential has been studied to some extent, limited information is available on marine algae from the Red Sea. This study aimed at the broad discovery of new bioactivities from a collection of twelve macroalgal species from the Central Red Sea. We used imaging-based High-Content Screening (HCS) with a diverse spectrum of cellular markers for detailed cytological profiling of fractionated algal extracts. The cytological profiles for 3 out of 60 algal fractions clustered closely to reference inhibitors and showed strong inhibitory activities on the HIV-1 reverse transcriptase in a single-enzyme biochemical assay, validating the suggested biological target. Subsequent chemical profiling of the active fractions of two brown algal species by ultra-high resolution mass spectrometry (FT-ICR-MS) revealed possible candidate molecules. A database query of these molecules led us to groups of compounds with structural similarities, which are suggested to be responsible for the observed activity. Our work demonstrates the versatility and power of cytological profiling for the bioprospecting of unknown biological resources and highlights Red Sea algae as a source of bioactives that may serve as a starting point for further studies.

  17. Effectiveness of community-based mangrove management for sustainable resource use and livelihood support: A case study of four villages in Central Java, Indonesia.

    Science.gov (United States)

    Damastuti, Ekaningrum; de Groot, Rudolf

    2017-12-01

    Community-Based Mangrove Management (CBMM) is implemented with different approaches and outcomes. This study examined the effectiveness of various CBMM practices to achieve sustainable management of mangrove resources. We analyzed local mangrove resource management strategies in four coastal villages (e.g. Sriwulan, Bedono, Timbulsloko, and Surodadi) on Central Java, Indonesia. Local data on institutions, socio-economic conditions and mangrove resources utilization was collected through participatory resource mapping and interviews with 16 key actors and 500 households. The main differences in CBMM-practices that affect the outcomes in each village were the type of community participation, the level of organizational and economic assistance from external institutions, the magnitude of the rehabilitation project, the time selected for rehabilitation and the maintenance strategies applied in each village. Surodadi achieved most in terms of both efficient resource utilization and local livelihood improvement. Bedono's management strategy was most effective in extending and maintaining the rehabilitated mangrove areas but less in terms of livelihood support while the strategy applied in Timbulsloko resulted in higher resource utilization compared to Surodadi. Sriwulan failed on most criteria. This study suggests that combining the management strategies practiced in Bedono and Surodadi and adding external scientific and technological assistance, income diversification, institutional reinforcement and continuous monitoring of the functioning of local institutions can improve the CBMM performance to sustainably manage mangrove resources and improve livelihoods. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Development of an ionic-liquid-based dispersive liquid-liquid microextraction method for the determination of antichagasic drugs in human breast milk: Optimization by central composite design.

    Science.gov (Uni