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Sample records for central america genetic

  1. Ecodesign in Central America

    Crul, M.R.M.

    2003-01-01

    This PhD thesis describes and analyses the change process started by the Ecodesign project in Central America, executed between 1998 and 2002. The project started using the concept and praxis developed in Europe. Nine ecodesign projects were performed in industry, and ecodesign was introduced to

  2. The complex biogeography of the plant pathogen Xylella fastidiosa: genetic evidence of introductions and Subspecific introgression in Central America.

    Nunney, Leonard; Ortiz, Beatriz; Russell, Stephanie A; Ruiz Sánchez, Rebeca; Stouthamer, Richard

    2014-01-01

    The bacterium Xylella fastidiosa is a plant pathogen with a history of economically damaging introductions of subspecies to regions where its other subspecies are native. Genetic evidence is presented demonstrating the introduction of two new taxa into Central America and their introgression into the native subspecies, X. fastidiosa subsp. fastidiosa. The data are from 10 genetic outliers detected by multilocus sequence typing (MLST) of isolates from Costa Rica. Six (five from oleander, one from coffee) defined a new sequence type (ST53) that carried alleles at six of the eight loci sequenced (five of the seven MLST loci) diagnostic of the South American subspecies Xylella fastidiosa subsp. pauca which causes two economically damaging plant diseases, citrus variegated chlorosis and coffee leaf scorch. The two remaining loci of ST53 carried alleles from what appears to be a new South American form of X. fastidiosa. Four isolates, classified as X. fastidiosa subsp. fastidiosa, showed a low level of introgression of non-native DNA. One grapevine isolate showed introgression of an allele from X. fastidiosa subsp. pauca while the other three (from citrus and coffee) showed introgression of an allele with similar ancestry to the alleles of unknown origin in ST53. The presence of X. fastidiosa subsp. pauca in Central America is troubling given its disease potential, and establishes another route for the introduction of this economically damaging subspecies into the US or elsewhere, a threat potentially compounded by the presence of a previously unknown form of X. fastidiosa.

  3. The complex biogeography of the plant pathogen Xylella fastidiosa: genetic evidence of introductions and Subspecific introgression in Central America.

    Leonard Nunney

    Full Text Available The bacterium Xylella fastidiosa is a plant pathogen with a history of economically damaging introductions of subspecies to regions where its other subspecies are native. Genetic evidence is presented demonstrating the introduction of two new taxa into Central America and their introgression into the native subspecies, X. fastidiosa subsp. fastidiosa. The data are from 10 genetic outliers detected by multilocus sequence typing (MLST of isolates from Costa Rica. Six (five from oleander, one from coffee defined a new sequence type (ST53 that carried alleles at six of the eight loci sequenced (five of the seven MLST loci diagnostic of the South American subspecies Xylella fastidiosa subsp. pauca which causes two economically damaging plant diseases, citrus variegated chlorosis and coffee leaf scorch. The two remaining loci of ST53 carried alleles from what appears to be a new South American form of X. fastidiosa. Four isolates, classified as X. fastidiosa subsp. fastidiosa, showed a low level of introgression of non-native DNA. One grapevine isolate showed introgression of an allele from X. fastidiosa subsp. pauca while the other three (from citrus and coffee showed introgression of an allele with similar ancestry to the alleles of unknown origin in ST53. The presence of X. fastidiosa subsp. pauca in Central America is troubling given its disease potential, and establishes another route for the introduction of this economically damaging subspecies into the US or elsewhere, a threat potentially compounded by the presence of a previously unknown form of X. fastidiosa.

  4. Central America's shrinking forests.

    1992-01-01

    This news brief reports that 66% of deforestation in Central America has happened in the past 40 years, based on World Conservation Union (WCU) data. Deforestation is expected to continue. The population of Central America and Mexico grew by 28% between 1977 and 1987. Growth is decreasing but remains high at 2.5% in all countries of the region except Panama. 29 million was the regional population in 1990; the projection is for 63 million by 2025. Population is migrating to urban centers. Forests declined by 13% and croplands increased from 4% to 13% of total land area and pasture land from 2% to 37%. There was an increase in unproductive land from 145 to 24%, i.e., 50% of El Salvador's land had soil degradation as does 30% of Guatemala's. In addition to deforestation and soil degradation, there has been soil erosion leading to sedimentation buildup near dam sites and in rivers, which diminishes hydroelectric power capability. Silting also affects groundwater resources, which impact on a safe drinking water supply. Population growth results in increased demand for fuelwood, urban land, and agricultural land. New techniques practiced widely are needed in order to meet the region's needs or demands. Slowing population growth buys time for adjusting to the necessary changes needed for sustaining the region's population. WCU urges conservation organizations to raise awareness about the role population plays in environmental degradation, and to support efforts to reduce birth rates. Women's status needs to be improved through income-generating projects, for instance, and cooperation is needed between conservation groups and organizations involved with improving maternal and child health.

  5. Mexico and Central America.

    Bronfman, M

    1998-01-01

    This article reviews the literature on migration and HIV/AIDS in Mexico and Central America, including Belize, Costa Rica, El Salvador, Guatemala, Honduras, Mexico, Nicaragua, and Panama. Most migrants travel to the US through Mexico. US-Mexico trade agreements created opportunities for increased risk of HIV transmission. The research literature focuses on Mexico. Most countries, with the exception of Belize and Costa Rica, are sending countries. Human rights of migrants are violated in transit and at destination. Migration policies determine migration processes. The Mexican-born population in the US is about 3% of US population and 8% of Mexico's population. About 22% arrived during 1992-97, and about 500,000 are naturalized US citizens. An additional 11 million have a Mexican ethnic background. Mexican migrants are usually economically active men who had jobs before leaving and were urban people who settled in California, Texas, Illinois, and Arizona. Most Mexican migrants enter illegally. Many return to Mexico. The main paths of HIV transmission are homosexual, heterosexual, and IV-drug-injecting persons. Latino migrants frequently use prostitutes, adopt new sexual practices including anal penetration among men, greater diversity of sexual partners, and use of injectable drugs.

  6. Drug resistance associated genetic polymorphisms in Plasmodium falciparum and Plasmodium vivax collected in Honduras, Central America.

    Jovel, Irina T; Mejía, Rosa E; Banegas, Engels; Piedade, Rita; Alger, Jackeline; Fontecha, Gustavo; Ferreira, Pedro E; Veiga, Maria I; Enamorado, Irma G; Bjorkman, Anders; Ursing, Johan

    2011-12-19

    In Honduras, chloroquine and primaquine are recommended and still appear to be effective for treatment of Plasmodium falciparum and Plasmodium vivax malaria. The aim of this study was to determine the proportion of resistance associated genetic polymorphisms in P. falciparum and P. vivax collected in Honduras. Blood samples were collected from patients seeking medical attention at the Hospital Escuela in Tegucigalpa from 2004 to 2006 as well as three regional hospitals, two health centres and one regional laboratory during 2009. Single nucleotide polymorphisms in P. falciparum chloroquine resistance transporter (pfcrt), multidrug resistance 1 (pfmdr1), dihydrofolate reductase (pfdhfr) and dihydropteroate synthase (pfdhps) genes and in P. vivax multidrug resistance 1 (pvmdr1) and dihydrofolate reductase (pvdhfr) genes were detected using PCR based methods. Thirty seven P. falciparum and 64 P. vivax samples were collected. All P. falciparum infections acquired in Honduras carried pfcrt, pfmdr1, pfdhps and pfdhfr alleles associated with chloroquine, amodiaquine and sulphadoxine-pyrimethamine sensitivity only. One patient with parasites acquired on a Pacific Island had pfcrt 76 T and pfmdr1 86Y alleles. That patient and a patient infected in West Africa had pfdhfr 51I, 59 R and 108 N alleles. Pvmdr1 976 F was found in 7/37 and two copies of pvmdr1 were found in 1/37 samples. Pvdhfr 57 L + 58 R was observed in 2/57 samples. The results indicate that P. falciparum from Honduras remain sensitive to chloroquine and sulphadoxine-pyrimethamine. This suggests that chloroquine and sulphadoxine-pyrimethamine should be efficacious for treatment of uncomplicated P. falciparum malaria, supporting current national treatment guidelines. However, genetic polymorphisms associated with chloroquine and sulphadoxine-pyrimethamine tolerance were detected in local P. vivax and imported P. falciparum infections. Continuous monitoring of the prevalence of drug resistant/tolerant P

  7. Gangs in Central America

    Ribando, Clare

    2005-01-01

    ... activities of Central American gangs. Citizens in several Central American countries have identified crime and gang violence among the top issues of popular concern, and Honduras and El Salvador have recently enacted tough anti-gang legislation...

  8. Demographic tensions in Central America.

    1986-08-01

    This discussion of Central America focuses on the rapid growth of its population, its stagnating economy, and those countries that are socioeconomically advanced. Between 1950-85 the population of Central America tripled, from 9.1 million to 26. 4 million, due to marked mortality declines and the absence of off-setting fertility declines. The distribution of Central Americas's growing populations sets its population growth apart from that of other developing regions. Currently, almost half of all Central Americans live in cities. Although the average growth rate for Central American countries has fallen and is expected to drop further, the decline does not counterbalance the effect of the absolute rise in population numbers. The average annual growth rate of more than 3% annually in the 1960s fell to about 2.6% in recent years, but this decline is due primarily to socioeconomically advanced Costa Rica and Panama. Central America's age structure further complicates the population crisis. About 43% of Central Americans are under the age of 15. When the increasingly larger young population group enters it reproductive years, the potential for future growth (albeit the falling rate of population increase) is unparalleled. UN population projections show the region's population at 40 million by the year 2000. The 1973 oil crisis began a downward spiral for the buoyant post World War II Central American economy. Between 1950-79, real per capita income growth in Central America doubled, with Central American economies growing an average of 5.3% annually. By the early 1980s, overseas markets of the trade-dependent countries of Central America had dried up due to protectionism abroad and slumping basic commodity prices. These and other factors plunged Central America into its current economic malaise of falling real per capita income, rising unemployment, curtailed export led economic growth, and a rising cost of living. In general, economic growth in Central America

  9. Fire management in central America

    Andrea L. Koonce; Armando González-Cabán

    1992-01-01

    Information on fire management operations in Central America is scant. To evaluate the known level of fire occurrence in seven countries in that area, fire management officers were asked to provide information on their fire control organizations and on any available fire statistics. The seven countries surveyed were Guatemala, Belize, Honduras, El Salvador, Nicaragua,...

  10. Volcanic hazards in Central America

    Rose, William I.; Bluth, Gregg J.S.; Carr, Michael J.; Ewert, John W.; Patino, Lina C.; Vallance, James W.

    2006-01-01

    This volume is a sampling of current scientific work about volcanoes in Central America with specific application to hazards. The papers reflect a variety of international and interdisciplinary collaborations and employ new methods. The book will be of interest to a broad cross section of scientists, especially volcanologists. The volume also will interest students who aspire to work in the field of volcano hazards mitigation or who may want to work in one of Earth’s most volcanically active areas.

  11. Genetic and morphological divergence among Cooper's Hawk (Accipiter cooperii) populations breeding in north-central and western North America

    Sonsthagen, Sarah A.; Rosenfield, Robert N.; Bielefeldt, John; Murphy, Robert K.; Stewart, Andrew C.; Stout, William C.; Driscoll, Timothy G.; Bozek, Michael A.; Sloss, Brian L.; Talbot, Sandra L.

    2012-01-01

    Cooper's Hawk (Accipiter cooperii) populations breeding in the northern portion of the species' range exhibit variation in morphological traits that conforms to predictions based on differences in prey size, tree stand density, and migratory behavior. We examined genetic structure and gene flow and compared divergence at morphological traits (PST) and genetic markers (FST) to elucidate mechanisms (selection or genetic drift) that promote morphological diversification among Cooper's Hawk populations. Cooper's Hawks appear to conform to the genetic pattern of an east-west divide. Populations in British Columbia are genetically differentiated from north-central populations (Wisconsin, Minnesota, and North Dakota; pairwise microsatellite FST= 0.031-0.050; mitochondrial DNA ΦST = 0.177-0.204), which suggests that Cooper's Hawks were restricted to at least two Pleistocene glacial refugia. The strength of the Rocky Mountains—Great Plains area as a barrier to dispersal is further supported by restricted gene-flow rates between British Columbia and other sampled breeding populations. Divergence in morphological traits (PST) was also observed across study areas, but with British Columbia and North Dakota differentiated from Wisconsin and Minnesota, a pattern not predicted on the basis of FST and ΦST interpopulation estimates. Comparison of PSTand FSTestimates suggests that heterogeneous selection may be acting on Cooper's Hawks in the northern portion of their distribution, which is consistent with hypotheses that variation in prey mass and migratory behavior among populations may be influencing overall body size and wing chord. We were unable to distinguish between the effects of genetic drift and selection on tail length in the study populations.

  12. The Mediterranean fruit fly in Central America

    Vail, V.; Moore, I.; Nadel, D.

    1976-01-01

    Various methods of controlling the medfly are available and include the use of insecticides, bait sprays and the sterile insect technique (SIT). Each of these control strategies may be used alone or in sequence. With regard to the application of the SIT, the Joint FAO/IAEA Division of Atomic Energy in Food and Agriculture through its Insect and Pest Control Section and Entomology Laboratory is in an excellent position to assist in containing the medfly in Central America. For the past 12 years, the laboratory has participated in all phases of medfly control by sterile insect releases in various climates. This involvement has included planning of medfly campaigns, development of pre-release techniques (bait spraying, trapping, etc.) and shipment and release of sterilized medflies. Small-scale field tests utilizing the SIT have been carried out by nine countries: Italy (Procida, Capri), Spain, Cyprus, Israel, Tunisia, Peru, Panama, Costa Rica and Nicaragua. Other field projects presently being counselled and serviced are located in Argentina, Venezuela and the Canary Islands. The research and development that are still needed to effectively stabilize and gain control of the medfly situation in Central America include: The development and use of effective quarantine procedures in various countries; Development of effective conventional medfly control procedures under the conditions found in Central America; Development of methods to determine the geographic origin of medflies introduced into new areas; Medfly mass production (viz. all aspects of rearing Central American strains); Assessing the performance (competitiveness, etc.) of various strains; Logistics, including the development of systems for releasing pre-adult stages; Genetic rearing methods: developmental research in this area is particularly promising since the preferential production of males would allow considerable savings in the rearing costs of medflies for release; Development of adequate surveillance

  13. Biomass energy in Central America

    Blanco, J M [Biomass Users` Network, Regional Office for Central America and the Caribbean, San Jose (Costa Rica)

    1995-12-01

    The objective of this paper is to introduce the concept of biomass to energy issues and opportunities in Central America. In this region, made up of seven countries (Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua and Panama), the biomass sector has the potential to play a crucial role in alleviating the environmental and development predicaments faced by all economies of the region. This paper assesses the available biomass resources at the regional and country levels and gives an overview of the current utilization of biomass fuels. It also describes the overall context in which the biomass-to-energy initiatives are immersed. At the regional level, biomass energy consumption accounts for more than 50% of total energy consumption. In regard to the utilization of biomass for energy purposes, it is clear that Central America faces a critical juncture at two levels, both mainly in rural areas: in the productive sector and at the household level. The absence of sustainable development policies and practices has jeopardized the availability of biomass fuels, particularly wood. Firewood is an important source of energy for rural industries such as coffee processing, which is one of the largest productive activities in the region. This paper comments on some of the most successful technological innovations already in place in the region, for instance, the rapid development of co-generation projects by the sugar cane industry, especially in El Salvador and Guatemala, the substitution of coffee husks for firewood in coffee processing plants in Costa Rica and El Salvador and the sustainable use of pine forests for co-generation in Honduras. Only one out of every two inhabitants in Central America now has access to electricity from the public grid. Biomass fuels, mainly firewood but also, to a lesser extent, other crop residues such as corn stalks, are the main source of energy for cooking and heating by most of the population. (It is foreseen that by the end

  14. Biomass energy in Central America

    Blanco, J.M.

    1995-01-01

    The objective of this paper is to introduce the concept of biomass to energy issues and opportunities in Central America. In this region, made up of seven countries (Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua and Panama), the biomass sector has the potential to play a crucial role in alleviating the environmental and development predicaments faced by all economies of the region. This paper assesses the available biomass resources at the regional and country levels and gives an overview of the current utilization of biomass fuels. It also describes the overall context in which the biomass-to-energy initiatives are immersed. At the regional level, biomass energy consumption accounts for more than 50% of total energy consumption. In regard to the utilization of biomass for energy purposes, it is clear that Central America faces a critical juncture at two levels, both mainly in rural areas: in the productive sector and at the household level. The absence of sustainable development policies and practices has jeopardized the availability of biomass fuels, particularly wood. Firewood is an important source of energy for rural industries such as coffee processing, which is one of the largest productive activities in the region. This paper comments on some of the most successful technological innovations already in place in the region, for instance, the rapid development of co-generation projects by the sugar cane industry, especially in El Salvador and Guatemala, the substitution of coffee husks for firewood in coffee processing plants in Costa Rica and El Salvador and the sustainable use of pine forests for co-generation in Honduras. Only one out of every two inhabitants in Central America now has access to electricity from the public grid. Biomass fuels, mainly firewood but also, to a lesser extent, other crop residues such as corn stalks, are the main source of energy for cooking and heating by most of the population. (It is foreseen that by the end

  15. Health and health services in Central America.

    Garfield, R M; Rodriguez, P F

    1985-08-16

    Despite rapid economic growth since World War II, health conditions improved only slowly in most of Central America. This is a result of poor medical, social, and economic infrastructure, income maldistribution, and the poor utilization of health investments. The economic crisis of the 1980s and civil strife have further endangered health in the region. Life expectancy has fallen among men in El Salvador and civil strife has become the most common cause of death in Guatemala, Nicaragua, and El Salvador. Large-scale US assistance has done little to improve conditions, and refugees continue to pour into North America. It is estimated that there are more than a million refugees within Central America, while a million have fled to the United States. Costa Rica and Nicaragua are partial exceptions to this dismal health picture. An effective approach to the many health problems in Central America will require joint planning and cooperation among all countries in the region.

  16. Post-War Central America

    Dirk Kruijt

    2003-10-01

    Full Text Available – Terror in the Countryside. Campesino Responses to Political Violence in Guatemala, 1954-1985, by Rachel A. May. Athens, Ohio: Ohio University Center for International Studies/Research in International Studies/Latin America Series #35, 2001. – La guerrilla fue mi camino. Epitafio para César Montes, by Julio César Macías. Guatemala: Piedra Santa/Colección Afluentes de Modernidad, 1999. – Testigo de conciencia (Periodismo de Opinión Documentado, by Marco A. Mérida. Guatemala: ARCASAVI, 2000. – Centroamérica 2002. Un nuevo modelo de desarrollo regional, edited by Klaus Bodemer and Eduardo Gamarra. Caracas: Nueva Sociedad, 2002. – Who Governs? Guatemala Five years After the Peace Accords, by Rachel Sieder, Megan Thomas, George Vickers and Jack Spence. Cambridge, Mass.: Hemispheric Initiatives/Washington Office on Latin America (WOLA, January 2002. – Pasos hacia una nueva convivencia: Democracia y participación en Centroamérica, edited by Ricardo Córdova Macías, Günther Maihold and Sabina Kurtenbach. San Salvador: FUNDAUNGO, Instituto de Estudios Iberoamericanos de Hamburgo and Instituto Iberoamericano de Berlin, 2001. – Los desafíos de la democracia en Centroamérica, by René Poitevin and Alexander Sequén-Mónchez. Guatemala: FLACSO, 2002. – Más allá de las elecciones: Diez años después de los acuerdos de paz, edited by Hector Dada Hirezi. San Salvador: FLACSO, 2002. – Guatemala, un proyecto inconcluso: La multiculturalidad, un paso hacia la democracia, by Hugo Cayzac. Guatemala: FLACSO, 2001. – La violencia en el contexto del posconflicto, según la percepción de comunidades urbanas pobres de Guatemala, by Caroline Moser and Cathy McIlwaine. Washington/Bogotá: Banco Mundial-Región de Latinoamérica y el Caribe/Tercer Mundo Editores, 2001. – El lado oscuro de la eterna primavera. Violencia, criminalidad y delincuencia en la postguerra, by Manolo Vela, Alexander Sequén-Mónchez and Hugo Antonio Solares

  17. Occupational health in Central America.

    Wesseling, Catharina; Aragón, Aurora; Morgado, Hugo; Elgstrand, Kaj; Hogstedt, Christer; Partanen, Timo

    2002-01-01

    The 12.4 million economically active population (EAP) of the seven Central American countries includes a large informal sector. Social security covers only 14-60%. No surveillance of occupational safety and health (OSH) hazards or accidents exists. Extrapolating the incidence of occupational accidents among insured Costa Rican workers to the Central American EAP yields two million accidents yearly, still a gross underestimate. Occupational diseases are underreported, misdiagnosed, and not recognized as such. A number of regional OSH programs aim at modernization of the labor administrations and address the formal sector, in particular textile maquila, in connection with free trade agreements. The weak role of the ministries of health is expected to strengthen under the Pan American Health Organization OSH program. Employers largely influence new policies. Workers' influence on OSH policies has been weak, with only about 10% unionization rate and scarce resources and OSH knowledge. Informal workers, however, are getting organized. OSH research is underdeveloped and not linked to policy making. Construction, agriculture, and general un/underemployment are considered priorities for intervention. The informal sector needs to be included in national and regional OSH policies. Regional collaboration and international development support are of strategic importance to achieve sustainable improvement in OSH.

  18. Genome-Wide Analysis Provides Evidence on the Genetic Relatedness of the Emergent Xylella fastidiosa Genotype in Italy to Isolates from Central America.

    Giampetruzzi, Annalisa; Saponari, Maria; Loconsole, Giuliana; Boscia, Donato; Savino, Vito Nicola; Almeida, Rodrigo P P; Zicca, Stefania; Landa, Blanca B; Chacón-Diaz, Carlos; Saldarelli, Pasquale

    2017-07-01

    Xylella fastidiosa is a plant-pathogenic bacterium recently introduced in Europe that is causing decline in olive trees in the South of Italy. Genetic studies have consistently shown that the bacterial genotype recovered from infected olive trees belongs to the sequence type ST53 within subspecies pauca. This genotype, ST53, has also been reported to occur in Costa Rica. The ancestry of ST53 was recently clarified, showing it contains alleles that are monophyletic with those of subsp. pauca in South America. To more robustly determine the phylogenetic placement of ST53 within X. fastidiosa, we performed a comparative analysis based on single nucleotide polymorphisms (SNPs) and the study of the pan-genome of the 27 currently public available whole genome sequences of X. fastidiosa. The resulting maximum-parsimony and maximum likelihood trees constructed using the SNPs and the pan-genome analysis are consistent with previously described X. fastidiosa taxonomy, distinguishing the subsp. fastidiosa, multiplex, pauca, sandyi, and morus. Within the subsp. pauca, the Italian and three Costa Rican isolates, all belonging to ST53, formed a compact phylotype in a clade divergent from the South American pauca isolates, also distinct from the recently described coffee isolate CFBP8072 imported into Europe from Ecuador. These findings were also supported by the gene characterization of a conjugative plasmid shared by all the four ST53 isolates. Furthermore, isolates of the ST53 clade possess an exclusive locus encoding a putative ATP-binding protein belonging to the family of histidine kinase-like ATPase gene, which is not present in isolates from the subspecies multiplex, sandyi, and pauca, but was detected in ST21 isolates of the subspecies fastidiosa from Costa Rica. The clustering and distinctiveness of the ST53 isolates supports the hypothesis of their common origin, and the limited genetic diversity among these isolates suggests this is an emerging clade within subsp

  19. Sources of Economic Fluctuations in Central America

    Wilfredo Toledo

    2014-06-01

    Full Text Available Using panel data from Central America, this paper studies the determining factors of inflation and aggregate output fluctuations by estimating two Structural Vector Autoregressive (SVAR models. Price and output variables are included in one of the models, whereas M2 and the price of oil are additional variables in the other one. Findings of this study suggest that price is determined by the demand, while output seems to be influenced mainly by the supply shocks in that area. It was also evidenced that the price of oil does not have a significant impact on the general price level in that region.

  20. Human Conservation in Central America, Summary of a Conference (Guatemala, Central America).

    Conservation Foundation, Washington, DC.

    This booklet is a resume consisting chiefly of extracts from papers that were presented at a conference on Human Conservation in Central America, held in Guatemala in 1965, as well as from discussions that took place during the conferences. With cooperation of numerous organizations and guidance from the Conservation Foundation, a discussion of…

  1. Regional Specialization. The Middle Americas: Mexico, Panama, Central America and the Caribbean Basin

    Owen, Mark H; Inman, Kenneth A

    1997-01-01

    .... Generally viewed as lagging in efforts to develop stable governments and self-sustaining economies, Mexico, Central America to include Panama and the Caribbean, henceforth Middle America, have in the...

  2. Legislation on renewable energy sources in Central America

    Rebollo, Jose

    2000-01-01

    This paper presents the development of renewable energy in Central America and the cooperation given by the European Comission in the promotion of renewable energy sources. Also discuss the current situation in energy demand in Central America and possible solutions linked to legislation that promotes the inversion of the private sector. The legal framework in each country of Central America is presented and its impact in the increasing of generation of energy through tax reductions, trading and prices

  3. Colored Height and Shaded Relief, Central America

    2002-01-01

    Panama, Costa Rica, Nicaragua, El Salvador, Honduras, Guatemala, Belize, southern Mexico and parts of Cuba and Jamaica are all seen in this image from NASA's Shuttle Radar Topography Mission. The dominant feature of the northern part of Central America is the Sierra Madre Range, spreading east from Mexico between the narrow Pacific coastal plain and the limestone lowland of the Yucatan Peninsula. Parallel hill ranges sweep across Honduras and extend south, past the Caribbean Mosquito Coast to lakes Managua and Nicaragua. The Cordillera Central rises to the south, gradually descending to Lake Gatun and the Isthmus of Panama. A highly active volcanic belt runs along the Pacific seaboard from Mexico to Costa Rica.High-quality satellite imagery of Central America has, until now, been difficult to obtain due to persistent cloud cover in this region of the world. The ability of SRTM to penetrate clouds and make three-dimensional measurements has allowed the generation of the first complete high-resolution topographic map of the entire region. This map was used to generate the image.Two visualization methods were combined to produce the image: shading and color coding of topographic height. The shade image was derived by computing topographic slope in the north-south direction. Color coding is directly related to topographic height, with green at the lower elevations, rising through yellow, red, and magenta, to white at the highest elevations.For an annotated version of this image, please select Figure 1, below: [figure removed for brevity, see original site] (Large image: 9 mB jpeg)Elevation data used in this image were acquired by the Shuttle Radar Topography Mission aboard the Space Shuttle Endeavour, launched on February 11, 2000. The mission used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar that flew twice on the Space Shuttle Endeavour in 1994. The Shuttle Radar Topography Mission was designed to collect

  4. Energy sector developments in Central America and the Caribbean

    Perez, J.

    1997-01-01

    Energy sector developments in Central America and the Caribbean were discussed. Central America is composed of six small countries whose total population is 32 million. The Caribbean population is 20.5 million. Central America is generally poor in hydrocarbon reserves but the geological prospects in several of the countries are encouraging. The oil and petroleum products supply and demand picture, the main characteristics of the hydrocarbon market, structure of the oil industry, hydrocarbon market reforms, pricing issues and recent trend towards reforms in the electric power industry in Central America were discussed. An overview of the Inter-American Development Bank's (IDB) effort to provide technical assistance and loans to strengthen the energy sector development in Central America and the Caribbean was also given. 17 refs., 2 tabs., 23 figs

  5. Assessing the ‘Arrival of Democracy’ in Central America

    Kees Biekart

    2014-03-01

    Full Text Available – Central America in the New Millennium: Living Transition and Reimagining Democracy, edited by Jennifer L. Burrell and Ellen Moodie. CEDLA Latin America Studies (CLAS Vol. 102. New York and Oxford: Berghahn Books, 2013.– The Politics of Modern Central America: Civil War, Democratization, and Underdevelopment, by Fabrice Lehoucq. Cambridge and New York: Cambridge University Press, 2012.– Handbook of Central American Governance, edited by Diego Sánchez-Ancochea and Salvador Martí i Puig. Milton Park and New York: Routledge, 2014.

  6. Introduction: seismology and earthquake engineering in Central and South America.

    Espinosa, A.F.

    1983-01-01

    Reports the state-of-the-art in seismology and earthquake engineering that is being advanced in Central and South America. Provides basic information on seismological station locations in Latin America and some of the programmes in strong-motion seismology, as well as some of the organizations involved in these activities.-from Author

  7. High level of molecular and phenotypic biodiversity in Jatropha curcas from Central America compared to Africa, Asia and South America

    2014-01-01

    Background The main bottleneck to elevate jatropha (Jatropha curcas L.) from a wild species to a profitable biodiesel crop is the low genetic and phenotypic variation found in different regions of the world, hampering efficient plant breeding for productivity traits. In this study, 182 accessions from Asia (91), Africa (35), South America (9) and Central America (47) were evaluated at genetic and phenotypic level to find genetic variation and important traits for oilseed production. Results Genetic variation was assessed with SSR (Simple Sequence Repeat), TRAP (Target Region Amplification Polymorphism) and AFLP (Amplified fragment length polymorphism) techniques. Phenotypic variation included seed morphological characteristics, seed oil content and fatty acid composition and early growth traits. Jaccard’s similarity and cluster analysis by UPGM (Unweighted Paired Group Method) with arithmetic mean and PCA (Principle Component Analysis) indicated higher variability in Central American accessions compared to Asian, African and South American accessions. Polymorphism Information Content (PIC) values ranged from 0 to 0.65. In the set of Central American accessions. PIC values were higher than in other regions. Accessions from the Central American population contain alleles that were not found in the accessions from other populations. Analysis of Molecular Variance (AMOVA; P jatropha oil significantly differed (P < 0.05) between regions. Conclusions The pool of Central American accessions showed very large genetic variation as assessed by DNA-marker variation compared to accessions from other regions. Central American accessions also showed the highest phenotypic variation and should be considered as the most important source for plant breeding. Some variation in early growth traits was found within a group of accessions from Asia and Africa, while these accessions did not differ in a single DNA-marker, possibly indicating epigenetic variation. PMID:24666927

  8. Private Higher Education in a Cold War World: Central America

    Harrington, James J.

    2009-01-01

    In Central America the Cold War support of the elites by the United States was designed to ward off the communist threat. At the same time social and economic demands by the working and middle classes created revolutionary movements in the face of rigid and violent responses by Central American governments. Issues of social justice pervaded the…

  9. (Human Security in Central America: A Return to the Past?

    Jordi Urgell García

    2007-02-01

    Full Text Available After having become one of the principal scenarios of the Cold War, the pacification and democratisation of Central America in the 1990s were forged under the protection of the Esquipulas Process and the birth of the concept of human security. The resulting model of security was founded on the Framework Treaty on Democratic Security, which incorporated some of the basic postulates of human security and became one of its first institutional implementations. Nevertheless, the performance of this model has been eclipsed and questioned by the evolution of events in Central America (such as the impact of 9-11 on security agendas or the emergence of new forms of violence in the region, which open the door to a new security instrument (the Rapid Reaction Force, generate fears about an eventual regression of Central America in the area of security and raise doubts about the habitual assumptions of human security.

  10. Comparative phylogeography of Oryzomys couesi and Ototylomys phyllotis; historic and geographic implications for the Central America conformation

    Tania Anaid Gutiérrez-García

    2013-12-01

    Full Text Available Central America is an ideal region for comparative phylogeographic studies because of its intricate geologic and biogeographic history, diversity of habitats and dynamic climatic and tectonic history. The aim of this work was to assess the phylogeography of two rodents codistributed throughout Central America, in order to identify if they show concordant genetic and phylogeographic patterns. The synopsis includes four parts: (1 an overview of the field of comparative phylogeography; (2 a detailed review that describes how genetic and geologic studies can be combined to elucidate general patterns of the biogeographic and evolutionary history of Central America; and a phylogeographic analysis of two species at both the (3 intraspecific and (4 comparative phylogeographic levels. The last incorporates specific ecological features and evaluates their influence on the species’ genetic patterns. Results showed a concordant genetic structure influenced by geographic distance for both rodents, but dissimilar dispersal patterns due to ecological features and life history. 

  11. Regional Strategic Appraisal of Central America

    2003-04-07

    Central America’s multiple transitions (from war to peace, from military rule to civilian, freely and democratically elected, constitutional government...Centroamericanas ‘CFAC’: Un Instrumento de Integracion y Seguridad Regional,” Center for Hemispheric Defense Studies, REDES 2001, Panel for Strategic

  12. Nutrition, poverty alleviation, and development in Central America and Panama.

    Immink, Maarten D C

    2010-03-01

    This paper reviews research with policy relevance for food and nutrition in Central America and similar areas. The research was conducted by the Institute of Nutrition of Central America and Panama (INCAP) during the last three decades of the past millennium (1970-99). Six policy areas were selected for this review: agricultural commercialization and rural development; wage and price policies; human resource development; social safety nets, particularly complementary food programs; multi-sectoral nutrition planning; and food and nutrition monitoring for policy formulation. The contents and major conclusions of the work are described, as well as their public policy implications.

  13. Oil supply in Central and South America

    Aguilera, Roberto F.

    2009-01-01

    This paper estimates a cumulative supply curve for conventional oil in the Central and South American (CSA) region. The curve includes volumes from provinces not previously assessed by other organizations, as well as reserve growth. Volumes for the previously unassessed provinces are estimated using a variable shape distribution (VSD) model. Then the volumes are allocated to CSA countries based on each country's share of proved reserves. Figures provided by the cumulative supply curve are stock variables for all time, unlike the traditional supply curve where they are flow variables that can continue from one period to the next. In this study, the fixed stock approach is used since it provides practical information with respect to the concerns that some have expressed about oil scarcity in the near future. Results indicate that Central and South American oil is more abundant than often assumed, and can be produced at costs below current market oil prices, and substantially below mid-2008 prices.

  14. Ticks and rickettsiae from wildlife in Belize, Central America.

    Lopes, Marcos G; May Junior, Joares; Foster, Rebecca J; Harmsen, Bart J; Sanchez, Emma; Martins, Thiago F; Quigley, Howard; Marcili, Arlei; Labruna, Marcelo B

    2016-02-02

    The agents of spotted fevers in Latin America are Rickettsia rickettsii, R. parkeri, Rickettsia sp. strain Atlantic rainforest, and R. massiliae. In Continental Central America, R. rickettsii remains the only known pathogenic tick-borne rickettsia. In the present study, ticks were collected from wild mammals in natural areas of Belize. Besides providing new data of ticks from Belize, we investigated rickettsial infection in some of these ticks. Our results provide ticks harboring rickettsial agents for the first time in Central America. Between 2010 and 2015, wild mammals were lived-trapped in the tropical broadleaf moist forests of central and southern Belize. Ticks were collected from the animals and identified to species by morphological and molecular analysis (DNA sequence of the tick mitochondrial 16S RNA gene). Some of the ticks were tested for rickettsial infection by molecular methods (DNA sequences of the rickettsial gltA and ompA genes). A total of 84 ticks were collected from 8 individual hosts, as follows: Amblyomma pacae from 3 Cuniculus paca; Amblyomma ovale and Amblyomma coelebs from a Nasua narica; A. ovale from an Eira Barbara; A. ovale, Amblyomma cf. oblongoguttatum, and Ixodes affinis from a Puma concolor; and A. ovale, A. coelebs, A. cf. oblongoguttatum, and I. affinis from two Panthera onca. Three rickettsial agents were detected: Rickettsia amblyommii in A. pacae, Rickettsia sp. strain Atlantic rainforest in A. ovale, and Rickettsia sp. endosymbiont in Ixodes affinis. The present study provides unprecedented records of ticks harboring rickettsial agents in the New World. An emerging rickettsial pathogen of South America, Rickettsia sp. strain Atlantic rainforest, is reported for the first time in Central America. Besides expanding the distribution of 3 rickettsial agents in Central America, our results highlight the possible occurrence of Rickettsia sp. strain Atlantic rainforest-caused spotted fever human cases in Belize, since its possible

  15. Is the Central America forearc sliver part of the North America plate?

    Guzman-Speziale, M.

    2012-04-01

    The Central America Forearc sliver is located between the Central America volcanic arc and the Middle America trench. Several authors have suggested that the forearc is being displaced to the northwest with respect to the Caribbean plate; they point to right-lateral, normal-faulting earthquakes along the Central America volcanic arc as prime evidence of this displacement. Apparently, the forearc continues to the northwest into southeastern Mexico, although this portion of the forearc is not being displaced. I present evidence that suggests that the forearc indeed continues into southeastern Mexico and that it belongs to the North America plate. Physiographically, there is a continuity of the forearc into the Coastal plains of southeastern (Chiapas) Mexico, across the Motagua and Polochic faults. Offshore, cross-sections of the Middle America trench are similar along the mexican (Chiapas) segment, and the Central American segment. Furthermore, at the northwestern end of the coastal plain there are no compressive structures, which suggests that the coastal plain is not being displaced to the northwest. As a matter of fact, fault-plane solutions for shallow earthquakes show extension rather than compression. Shallow, interplate earthquakes along the trench show similar parameters along both segments. P-axes and earthquake slip vectors have consistent azimuths, which relate better with Cocos-North America convergence than with Cocos-Caribbean. Azimuth of T-axes for normal-faulting earthquakes also agree well with Cocos-North America convergence. Similarity in several parameters is thus found across both segments, the Chiapas coastal plain and the Central America forearc sliver proper. This suggests that both segments are continuous and probably one and the same, and belonging to the North America plate. Perhaps more properly, the forearc sliver extends into southeastern Mexico and is part of the zone of deformation associated to the Cocos-North America-Caribbean plates

  16. The Determinants of Banks' Liquidity Buffers in Central America

    Corinne Deléchat; Camila Henao; Priscilla Muthoora; Svetlana Vtyurina

    2014-01-01

    Banks’ liquidity holdings are comfortably above legal or prudential requirements in most Central American countries. While good for financial stability, high liquidity may nonetheless hinder financial market development and monetary policy transmission. Using a panel of 96 commercial banks from Central America, Panama and the Dominican Republic for 2006-2010, we find that the demand for precautionary liquidity buffers is associated with measures of bank’s size, profitability, capitalization, ...

  17. National Geothermal Association Trade Mission to Central America

    1992-10-01

    The United States (US) geothermal industry, the world's most technically proficient, has been unable to achieve penetration into the markets of the developing nations. This report details the findings of an industry Trade Mission to Central America, tasked with determining the reasons for this shortfall and with developing a US industry geothermal export strategy designed to achieve immediate and long-term export benefits

  18. Assessing the 'Arrival of Democracy' in Central America

    K. Biekart (Kees)

    2014-01-01

    markdownabstract__Abstract__ Review Essay. In the 1970s and 1980s, Central America was associated with military governments, revolutionary movements, civil war, extreme inequality, and authoritarianism in the ‘backyard’ of the United States. Broad social mobilizations and political repression

  19. Visiting the Digital Divide: Women Entrepreneurs in Central America

    Tapper, Helena

    2006-01-01

    Micro and small enterprises comprise approximately 60-70% of enterprises in South and Central America. Most of these enterprises, particularly micro enterprises, are managed and owned by women. These women for the most part lack both skills and training in the use of computers and the Internet, and access to the use of information and…

  20. Water Security and Climate Change in Central America and the ...

    Recent studies show that water shortages in Central America and the Caribbean will be aggravated by urban growth, high poverty rates, weak institutions, and insufficient investment in water and sanitation infrastructure. Extreme climatic events are expected to further threaten water supply as well as affect economic sectors ...

  1. Youth employment to reduce violence in Central America | CRDI ...

    According to 2014 statistics, four out of the 10 countries with the highest homicide rates in the world are in Central America. The vast majority of victims of violence are young men between the ages of 15 and 24, some of whom also risk becoming perpetrators of violence. Access to jobs, in both formal and informal labour ...

  2. Harmonization of Legislation against Organized Crime in Central America

    Jaime Edwin Martínez Ventura

    2014-05-01

    Full Text Available With the expansion of organized crime in Central America, the countries in this continental sub-region have enacted a great deal of internal legislation, and have ratified international treaties at the universal, regional and Central American level, particularly after the United Nations Convention against Transnational Organized Crime took effect in 2000.This abundance of laws is very positive, and is an expression of these Central American States’ intent to fulfill their supranational obligations and provide security for their inhabitants. However, it is also negative in that it has led to dispersion, dislocation, discrepancies and inaccuracies regarding the prevailing legal regulations, because national laws have been developed with different concepts, structures, approaches, scope and definitions.Despite these conditions that are adverse to legal harmonization, Central America can move forward with matching its legislation against organized crime. Actually, there already exists an extensive common legal framework in this area, expressed in the fact that most international treaties on Organized Crime have come into force at the universal, regional and subregional levels, ratified by all or most countriesPolitical will is the common denominator that should mediate all efforts of harmonization and alignment of legislation in Central America; it is essential for proposing steps that are based on a common strategy or program.DOI: http://dx.doi.org/10.5377/rpsp.v1i2.1359

  3. Social determinants of workers' health in Central America.

    Aragón, Aurora; Partanen, Timo; Felknor, Sarah; Corriols, Marianela

    2011-01-01

    This communication summarizes the available data on work-related determinants of health in Central America. The Central American working population is young and moving from agriculture toward industry and services. Ethnicity, gender, migration, subemployment and precarious work, informality, rural conditions, low-level educational, poverty, ubiquitous worksite health hazards, insufficient occupational health services, low labor inspection density, and weak unions define the constellation of social determinants of workers' health in Central America. Data are, however, scanty both for hazards and work-related illnesses and injuries. Governments and industries have the responsibility of opening decent work opportunities, especially for those facing multiple inequalities in social determinants of health. A first step would be the ratification and implementation of the ILO Convention (187) on occupational safety and health by the seven national governments of the region.

  4. Earth and water resources and hazards in Central America

    Cunningham, Charles G.; Fary, R.W.; Guffanti, Marianne; Laura, Della; Lee, M.P.; Masters, C.D.; Miller, R.L.; Quinones-Marques, Ferdinand; Peebles, R.W.; Reinemund, J.A.; Russ, D.P.

    1984-01-01

    Long-range economic development in Central America will depend in large part on production of indigenous mineral, energy, and water resources and on mitigation of the disastrous effects of geologic and hydrologic hazards such as landslides, earthquakes, volcanic eruptions, and floods. The region has six world-class metal mines at present as well as additional evidence of widespread mineralization. Systematic investigations using modern mineral exploration techniques should reveal more mineral deposits suitable for development. Widespread evidence of lignite and geothermal resources suggests that intensive studies could identify producible energy sources in most Central American countries. Water supply and water quality vary greatly from country to country. Local problems of ground- and surface-water availability and of contamination create a need for systematic programs to provide better hydrologic data, capital improvements, and management. Disastrous earthquakes have destroyed or severely damaged many cities in Central America. Volcanic eruptions, landslides, mudflows, and floods have devastated most of the Pacific side of Central America at one time or another. A regional approach to earthquake, volcano, and flood-risk analysis and monitoring, using modern technology and concepts, would provide the facilities and means for acquiring knowledge necessary to reduce future losses. All Central American countries need to strengthen institutions and programs dealing with earth and water resources and natural hazards. Some of these needs may be satisfied through existing or pending projects and technical and economic assistance from U.S. or other sources. The need for a comprehensive study of the natural resources of Central America and the requirements for their development is evident. The U.S. Caribbean Basin Initiative offers both an excellent opportunity for a regional approach to these pervasive problems and an opportunity for international cooperation.

  5. Remittances in Central America: Whose Money is it Anyway?

    Jose Luis Rocha

    2015-08-01

    Full Text Available In opposition to optimistic visions that present remittances as an opportunity for developing countries, this paper shows they are part and parcel of a process of economic imperialism, whereby their use and final destinations are strictly conditioned. In order to go beyond a conception of remittances as epiphenomenon, and in order to trace the role they play, this paper focuses on the transnational strategies of capital. It finds that remittances enable an increase in foreign investment and import production by facilitating the rise of a new class of consumers in Central America. Remittances create and feed a purchasing power that would not exist in their absence. Factories, fast food restaurants, communications companies, banks, travel agencies, and supermarkets are opening new branches throughout Central America in order to benefit from transnational savings that would otherwise be used differently. In this way, remittances are conditioned and co-opted by transnational capital’s strategies to sustain an ever growing market, with Central America more generally – and once again – potentially at risk of becoming characterized by enclave economies and chronic commercial deficits. The remittance-based economic model furthermore cannot be sustainable in the long run unless Central American countries keep exporting workers ad infinitum, something that is obviously not possible.

  6. Narco-scapes: Cocaine Trafficking and Deforestation in Central America

    Wrathall, D.; McSweeney, K.; Nielsen, E.; Pearson, Z.

    2015-12-01

    Narcotics trafficking and drug interdiction efforts have resulted in a well-documented social crisis in Central America, but more recently, has been tightly linked to environmental catastrophe and accelerated deforestation in transit zones. This talk will outline synthesis findings from multi-country, interdisciplinary research on cocaine trafficking as an engine of forest loss in Central America. During the "narco-boom" of the mid-2000s, we observed a geographical evolution of cocaine flows into Central America, and the transit of cocaine through new spaces, accompanied by specific patterns of social and environmental change in new nodes of transit. We coarsely estimated that the total amount of cocaine flowing through Central America increased from 70 metric tons in 2000 to 350 mt in 2012, implying that total cocaine trafficking revenue in the region increased from roughly 600 million dollars to 3.5 billion in that time. We describe the mechanism by which these locally captured cocaine rents resulted in a rapid conversion of forest into cattle pasture. Narco-traffickers are drawn to invest in the cattle economy, as a direct means of laundering and formalizing proceeds. Ranching is a land intensive activity, and new narco-enriched cattle pastures can be isolated from other forms forest loss solely by their spatial and temporal change characteristics. A preliminary forest change study in Honduras, for example, indicated that areas of accelerated deforestation were in close proximity to known narcotics trafficking routes and were thirteen times more extensive on average than other forest clearings. Deforested areas commonly appeared in isolated and biodiverse lowland tropical rainforest regions that often intersected with protected areas and indigenous reserves. We find that narco-deforestation is a readily identifiable signal of the extent and health of the cocaine economy. This talk will feature summaries of both ethnographic and land cover change we have observed

  7. Interconnected power systems of the countries of America Central (SIEPAC)

    2002-01-01

    This presentation shows the project SIEPAC (Sistema de interconexion electrica de los paises de Centro America) describes the current transmission system, and planned SIEPAC transmission system, also describes the objectives: implementation of an central american electrical market named Mercado Electrico Regional that contributes to sustaintable development of the region. Also describes the power transmission lines, the structure of line transmission and its market to be covered. Financing of the project from lending institutions is explained

  8. National Geothermal Association Trade Mission to Central America

    1992-10-01

    The United States (US) geothermal industry, the world's most technically proficient, has been unable to achieve penetration into the markets of the developing nations. This report details the findings of an industry Trade Mission to Central America, tasked with determining the reasons for this shortfall and with developing a US industry geothermal export strategy designed to achieve immediate and long-term export benefits.

  9. National Geothermal Association Trade Mission to Central America

    1992-10-01

    The United States (US) geothermal industry, the world`s most technically proficient, has been unable to achieve penetration into the markets of the developing nations. This report details the findings of an industry Trade Mission to Central America, tasked with determining the reasons for this shortfall and with developing a US industry geothermal export strategy designed to achieve immediate and long-term export benefits.

  10. Acute pesticide poisoning and pesticide registration in Central America

    Wesseling, Catharina; Corriols, Marianela; Bravo, Viria

    2005-01-01

    The International Code of Conduct on the Distribution and Use of Pesticides of the Food and Agriculture Organization (FAO) of the United Nations has been for 20 years the most acknowledged international initiative for reducing negative impact from pesticide use in developing countries. We analyzed pesticide use and poisoning in Central America, particularly in Costa Rica and Nicaragua, and evaluated whether registration decisions are based on such data, in accordance with the FAO Code. Extensive use of very hazardous pesticides continues in Central America and so do poisonings with organophosphates, carbamates, endosulfan and paraquat as the main causative agents. Central American governments do not carry out or commission scientific risk assessments. Instead, guidelines from international agencies are followed for risk management through the registration process. Documentation of pesticide poisonings during several decades never induced any decision to ban or restrict a pesticide. However, based on the official surveillance systems, in 2000, the ministers of health of the seven Central American countries agreed to ban or restrict twelve of these pesticides. Now, almost 4 years later, restrictions have been implemented in El Salvador and in Nicaragua public debate is ongoing. Chemical and agricultural industries do not withdraw problematic pesticides voluntarily. In conclusion, the registration processes in Central America do not comply satisfactorily with the FAO Code. However, international regulatory guidelines are important in developing countries, and international agencies should strongly extend its scope and influence, limiting industry involvement. Profound changes in international and national agricultural policies, steering towards sustainable agriculture based on non-chemical pest management, are the only way to reduce poisonings

  11. Leishmania chagasi/infantum : further investigations on Leishmania tropisms in atypical cutaneous and visceral leishmaniasis foci in Central America

    Campos Ponce, M.; Ponce, C.; Ponce, E; Maingon, R.D.

    2005-01-01

    In Central America, apparently genetically identical Leishmania chagasi/infantum parasites cause cutaneous (CL) and visceral leishmaniasis (VL), the latter being more frequent in young children. The present study investigated if there were pathology-related differences in virulence between Honduran

  12. Leishmania chagasi/infantum: further investigations on Leishmania tropisms in atypical cutaneous and visceral leishmaniasis foci in Central America.

    Campos Ponce, M.; Ponce, C.; Ponce, E.; Maingon, R.D.

    2005-01-01

    In Central America, apparently genetically identical Leishmania chagasi/infantum parasites cause cutaneous (CL) and visceral leishmaniasis (VL), the latter being more frequent in young children. The present study investigated if there were pathology-related differences in virulence between Honduran

  13. Central and South America GPS geodesy - CASA Uno

    Kellogg, James N.; Dixon, Timothy H.

    1990-01-01

    In January 1988, scientists from over 25 organizations in 13 countries and territories cooperated in the largest GPS campaign in the world to date. A total of 43 GPS receivers collected approximately 590 station-days of data in American Samoa, Australia, Canada, Colombia, Costa Rica, Ecuador, New Zealand, Norway, Panama, Sweden, United States, West Germany, and Venezuela. The experiment was entitled CASA Uno. Scientific goals of the project include measurements of strain in the northern Andes, subduction rates for the Cocos and Nazca plates beneath Central and South America, and relative motion between the Caribbean plate and South America. A second set of measurements are planned in 1991 and should provide preliminary estimates of crustal deformation and plate motion rates in the region.

  14. Violence, Rule of Law, and Punitive Policies in Central America

    Verónica De la Torre

    2011-01-01

    Full Text Available This article suggests that high levels of violence and crime in the so called North Triangle of Central America (Guatemala, El Salvador and Honduras, together with the incapacity of the state of enforcing the rule of law, are causing growing anxiety among the population and are attracting the support of the community to implement authoritarian measures to fight crime. The response of the governments of the region in the face of the rise of crime and public demand for security has been the policies of "iron fist", and the use of "populist punitiveness" as a strategy to gain the backing of an electorate deeply concerned by insecurity.

  15. Environmental impacts during geothermal development: Some examples from Central America

    Goff, S.; Goff, F.

    1997-01-01

    The impacts of geothermal development projects are usually positive. However, without appropriate monitoring plans and mitigation actions firmly incorporated into the project planning process, there exists the potential for significant negative environmental impacts. The authors present five examples from Central America of environmental impacts associated with geothermal development activities. These brief case studies describe landslide hazards, waste brine disposal, hydrothermal explosions, and air quality issues. Improved Environmental Impact Assessments are needed to assist the developing nations of the region to judiciously address the environmental consequences associated with geothermal development

  16. Review of the genera of Conoderinae (Coleoptera, Curculionidae from North America, Central America, and the Caribbean

    Salvatore S. Anzaldo

    2017-07-01

    Full Text Available The thirty-nine extant genera of Conoderinae known to occur in North America, Central America, and the Caribbean are reviewed based on external morphology. An identification key is provided along with diagnoses, distributions, species counts, and natural history information, when known, for each genus. Morphological character systems of importance for weevil classification are surveyed, potential relationships among the tribes and genera are discussed, and groups most in need of taxonomic and phylogenetic attention are identified. The following genera are transferred to new tribes: Acoptus LeConte, 1876 from the Lechriopini to the Othippiini (new placement and the South American genus Hedycera Pascoe, 1870 from the Lechriopini to the Piazurini (new placement. Philides Champion, 1906 and Philinna Champion, 1906 are transferred from the Lechriopini to Conoderinae incertae sedis (new placement although their placement as conoderines is uncertain. The species Copturomimus cinereus Heller, 1895 is designated as the type species of the genus Copturomimus Heller, 1895.

  17. Implications of the Central America-Dominican Republic-Free Trade Agreement for the nutrition transition in Central America.

    Hawkes, Corinna; Thow, Anne Marie

    2008-11-01

    To identify potential impacts of the Central America-Dominican Republic-Free Trade Agreement (CAFTA-DR) on food consumption patterns associated with the nutrition transition, obesity, and diet-related chronic diseases. Examination of CAFTA-DR agreement to identify measures that have the potential to affect food availability and retail prices. CAFTA-DR includes agreements on tariffs, tariff-rate quotas (TRQs), and sanitary and phytosanitary regulations with direct implications for the availability and prices of various foods. Agreements on investment, services, and intellectual property rights (IPR) are also relevant because they create a business climate more conducive to long-term investment by the transnational food industry. Trade liberalization under CAFTA-DR is likely to increase availability and lower relative prices of two food groups associated with the nutrition transition: meat and processed foods. These outcomes are expected to occur as the direct result of increased imports from the United States and increased production by U.S. companies based in Central America, and the indirect result of increased domestic meat production (due to increased availability of cheaper animal feed) and increased production of processed foods by domestic companies (due to a more competitive market environment). CAFTA-DR is likely to further the nutrition transition in Central America by increasing the consumption of meat; highly processed foods; and new, non-traditional foods. The public health community should be more aware of the implications of trade agreements for dietary health. Governments and related stakeholders should assess the coherence between changes fostered by specific trade agreements with national policies on diet and nutrition.

  18. COELIAC DISEASE IN CENTRAL AND SOUTH AMERICA: time for a concerted approach to its epidemiology

    Affifa FARRUKH

    2015-06-01

    Full Text Available Central and South America offer an opportunity to resolve some of the current controversies that surround the epidemiology of celiac disease. Through a concerted action which brings together clinicians, researchers and patients there is an opportunity to establish robust data sets which will allow detailed analysis of environmental and genetic factors. In this review available data from the continent together with data from Spain and Italy are drawn together to give a current picture in the hope that it will stimulate further research.

  19. Team Massachusetts & Central America Solar Decathlon 2015 Final Technical Report

    Lee, Kenneth [Western New England Univ., Springfield, MA (United States)

    2016-04-29

    Our team was Team MASSCA (Massachusetts and Central America), which was a partnership of Western New England University (WNE) located in Massachusetts USA, The Technological University of Panama (UTP), and Central American Technological University (UNITEC) of Honduras. Together we had a group of 6 faculty members and approximately 30 undergraduate students. Our house is ‘The EASI’ House, which stands for Efficient, Affordable, Solar Innovation. The EASI house is rectangular with two bedrooms and one bath, and offers a total square footage of 680. Based on competition estimates, The EASI house costs roughly $121,000. The EASI house has a 5kW solar system. Faculty and students from all three institutions were represented at the competition in Irvine California. Team MASSCA did well considering this was our first entry in the Solar Decathlon competition. Team MASSCA won the following awards: First Place – Affordability Contest Second Place – Energy Balance Contest. The competition provided a great experience for our students (and faculty as well). This competition provided leadership, endurance, and technical knowledge/skills for our students, and was the single most important hands-on experience during their undergraduate years. We are extremely pleased with the awards we received. At the same time we have learned from our efforts and would do better if we were to compete in the future. Furthermore, as a result of our team’s Inter-Americas collaborative effort, UTP and WNE have partnered to form Team PANAMASS (PANAma and MASSachusetts) and have developed The 3 SMART House for the inaugural Solar Decathlon Latin America & Caribbean competition held in Colombia.

  20. Evolution of the Earthquake Catalog in Central America

    Rojas, W.; Camacho, E. I.; Marroquín, G.; Molina, E.; Talavera, E.; Benito, M. B.; Lindholm, C.

    2013-05-01

    Central America (CA) is known as a seismically active region in which several historic destructive earthquakes have occurred. This fact has promoved the development of seismic hazard studies that provide necessary estimates for decision making and risk assessment efforts, requiring a complete and standardized seismic catalog. With this aim, several authors have contributed to the study of the historical seismicity of Central America (e.g. Grases, Feldaman; White y Harlow, 1993; White et al. 2004; Ambraseys y Adams, 2001; Peraldo y Montero, 1999), who complied historical data. A first catalogue was developed by Rojas (1993) that comprises the 1522 to 1993 period. This information was integrated in 2007, together with data from the International Seismological Centre (CASC) and the national catalogs of CA countries in a new regional catalogue. Since 2007 a continuous effort has been done in order to complete and update this CA earthquake catalog. In particular, two workshops were held in 2008 and 2011 in the Universidad Politécnica de Madrid (Spain), joining experts from the different CA countries who worked each one in its own catalogue covering the entire region and the border with northwestern Colombia and southern Mexico. These national catalogues were later integrated in a common regional catalogue in SEISAN format. At this aim it was necessary to solve some problems, like to avoid duplicity of events, specially close to the boundaries, to consider the different scales of magnitude adopted by different countries, to take into account the completeness by the different national networks, etc. Some solutions were adopted for obtaining a homogenized catalogue to Mw, containing historical and instrumental events with Mw > 3.5 from 1522 up to 2011. The catalogue updated to December 2007 was the basis for the first regional hazard study carried out by Benito et al., (2011) as part of the collaborative RESIS II project under coordination of NORSAR. The ones updated to

  1. Investigation of the nutrition problems of Central America and Panama.

    Arroyave, Guillermo

    2010-03-01

    From its earliest years, INCAP gave a high priority to a multidisciplinary effort to learn as much as possible about the dietary habits, nutritional status, and their consequences in the populations of Central America and Panama. Most of the papers in this Special Issue contain some of this information. The first studies were in schoolchildren but were soon extended to preschool children, pregnant and lactating women, and other adults. This paper describes the principal findings of the initial dietary, biochemical, and clinical community-based studies. From 1965-67, very extensive studies were carried out in all six countries including dietary, biochemical, clinical, and anthological studies were carried out in all six countries, the results of which are summarized.

  2. Forest pests in central America: Field guide. Technical manual

    1992-01-01

    In Central America, plant health problems have grown to an unprecedented level during the past few years along with the establishment of extensive homogeneous forest plantations, at times leading to the such drastic solutions as widespread felling of trees or massive use of pesticides. This field guide on forest pests was commissioned by the Multipurpose Tree Crop Dissemination (MADELENA) project and focuses on pests found in Costa Rica, home of PIROF (Programa Interinstitucional de Proteccion Forestal), a pioneer in forest pest research. The guide offers fast identification of forest pests and some general information on their biology and epidemiology. It consists of two sections: (1) lists of the specific pests (insects, vertebrates, pathogens, and parasites) of 18 priority forest tree species, and lists of the specific tree part or developmental stage they afflict.

  3. First discovery of Quercus feeding Nepticulidae (Lepidoptera) in Central America.

    Stonis, Jonas R; Diškus, Arūnas; Remeikis, Andrius; Schuster, Jack

    2013-11-18

    Despite the high taxonomic diversity of oaks in Mexico and Central America, no Quercus feeding Nepticulidae have ever been recorded from the region. Here, we present seven species whose larvae are leaf-miners of Quercus (section Lobatae) in Guatemala. Except Stigmella nigriverticella (Chambers 1875), which was previously known from the United States, all other discovered species are new. We describe and name five new species (Stigmella jaguari Remeikis & Stonis, sp. nov., S. lauta Diškus & Stonis, sp. nov., S. sublauta Remeikis & Stonis, sp. nov., S. aurifasciata Diškus & Stonis, sp. nov. and S. guatemalensis Diškus & Stonis, sp. nov.); the remaining new species is described but left unnamed because of lack of adults (i. e. moths and genitalia are described from developed pupae). All seven treated species are illustrated with photographs of the leaf-mines, adults, and genitalia.

  4. Interplate coupling along segments of the Central America Subduction zone

    Zarifi, Zoya; Raeesi, Mohammad; Atakan, Kuvvet

    2013-04-01

    We analyzed 5 major earthquakes that occurred during 1992 to 2012 in a segment of the Central America subduction zone along the coasts of Guatemala and El Salvador. These events include 1992/09/02 (Mw 7.7), 1993/09/10 (Mw 7.2), 2001/01/13 (Mw 7.7), 2012/08/27 (Mw 7.3) and 2012/11/07 (Mw 7.3). We derived the asperities of these earthquakes using two completely independent methods of body-waveform inversion and a gravity-derived measure, Trench Parallel Bouguer Anomaly (TPBA). Using TPBA we discuss the status of interplate coupling along the segment and interpret each of the major earthquakes as a piece of the governing rupture process. We delineate the critical unbroken asperities along the segment that will likely generate great earthquake(s) in the future.

  5. The burden of oesophageal cancer in Central and South America.

    Barrios, Enrique; Sierra, Monica S; Musetti, Carina; Forman, David

    2016-09-01

    Oesophageal cancer shows marked geographic variations and is one of the leading causes of cancer death worldwide. We described the burden of this malignancy in Central and South America. Regional and national level incidence data were obtained from 48 population-based cancer registries in 13 countries. Mortality data were obtained from the WHO mortality database. Incidence of oesophageal cancer by histological subtype were available from high-quality population-based cancer registries. Males had higher incidence and mortality rates than females (male-to-female ratios: 2-6:1 and 2-5:1). In 2003-2007, the highest rates were in Brazil, Uruguay, Argentina and Chile. Mortality rates followed the incidence patterns. Incidence of oesophageal squamous cell carcinoma (SCC) was higher than adenocarcinoma (AC), except in females from Cuenca (Ecuador). SCC and AC incidence were higher in males than females, except in the Region of Antofagasta and Valdivia (Chile), Manizales (Colombia) and Cuenca (Ecuador). Incidence and mortality rates tended to decline in Argentina, Chile, Brazil (incidence) and Costa Rica from 1997 to 2008. The geographic variation and sex disparity in oesophageal cancer across Central and South America may reflect differences in the prevalence of tobacco smoking and alcohol consumption which highlights the need to implement and/or strengthen tobacco and alcohol control policies. Maté consumption, obesity, diet and Helicobacter pylori infection may also explain the variation in oesophageal cancer rates but these relationships should be evaluated. Continuous monitoring of oesophageal cancer rates is necessary to provide the basis for cancer prevention and control in the region. Copyright © 2015 International Agency for Research on Cancer. Published by Elsevier Ltd.. All rights reserved.

  6. Smart power and foreign policy of the People's Republic of China: the case of Central America

    Manuel Villegas Mendoza

    2016-02-01

    Full Text Available This paper presents the most relevant aspects of the academic debate on smart power, in order to apply this concept to analyze the foreign policy of the Republic of China on Latin America and the Caribbean, but especially to Central America; where the dispute between China and Taiwan for international recognition is evident. It is argued that the smart power of China to Central America is expressed in the attractiveness of having privileged access to the Chinese market and its funding programs and official development assistance. While this country has a large presence in Latin America and the Caribbean, in Central America such influence is counteracted in the light of the close relationship that all Central American countries except Costa Rica, maintain with Taiwan. Based on the development of China as a world power, it is expected that this condition changed, so that this country would increase its influence in Central America.

  7. Renewable energies. A challenge and an opportunity for Central America; Energias renovables. Un reto y una oportunidad para America Central

    Guevara, Leo; Castro S, Rene [Instituto Centroamericano de Administracion de Empresas (INCAE) (Costa Rica)

    2007-07-15

    There are analyzed in this working paper the following aspects: the Central America countries and their relations with the regional energy potencies -Mexico and Venezuela- and the impact they have in the energy supply. There are also explore the following aspects: the San Jose Agreement linked to the fossil fuels supply, the emerging scope boosted by Brazil and Colombia regarding to the alternative fuels. [Spanish] Este trabajo analiza los paises centroamericanos y sus relaciones con las potencias energeticas regionales como Mexico y Venezuela, y como estas impactan el suministro de energia en la region. Tambien se exploran mecanismos como el Pacto de San Jose, ligado al suministro de combustibles fosiles y las oportunidades emergentes impulsadas por Brasil y Colombia con combustibles alternativos.

  8. Central America in Transition: From Maize to Wheat Challenges and Opportunities

    Amado Salvador Peña

    2015-08-01

    Full Text Available The Central American countries: Guatemala, El Salvador, Honduras, Nicaragua, Costa Rica, and Panama are in transition from a dietary culture based mainly on maize to a wheat-containing diet. Several other changes are occurring, such as a decrease of parasitic and infectious diseases. The environmental changes permit a prediction of an increase of celiac disease and other autoimmune diseases such as type I diabetes and thyroid disease in these genetically heterogeneous countries. At present, celiac disease and gluten-related disorders are considered to be of no relevance at the level of public health in these nations. This review documents the presence of celiac disease in Central America. It draws attention to some of the challenges in planning systematic studies in the region since up until recently celiac disease was unknown. The aim of this review is to disseminate knowledge obtained with preliminary data, to stimulate clinical and basic scientists to study these diseases in Central America and to alert authorities responsible for the planning of education and health, to find possibilities to avoid a rise in these disorders before the epidemics start, as has occurred in the Mediterranean countries.

  9. The multiple genetic causes of central hypothyroidism.

    Persani, Luca; Bonomi, Marco

    2017-03-01

    An insufficient stimulation by thyrotropin (TSH) of an otherwise normal thyroid gland represents the cause of Central Hypothyrodism (CeH). CeH is about 1000-folds rarer than Primary Hypothyroidism and often represents a real challenge for the clinicians, mainly because they cannot rely on adequately sensitive parameters for diagnosis or management, as it occurs with circulating TSH in PH. Therefore, CeH diagnosis can be frequently missed or delayed in patients with a previously unknown pituitary involvement. A series of genetic defects have been described to account for isolated CeH or combined pituitary hormone defects (CPHDs) with variable clinical characteristics and degrees of severity. The recently identified candidate gene IGSF1 appears frequently involved. This review provides an updated illustration of the different genetic defects accounting for CeH. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Field Evaluations of Topical Arthropod Repellents in North, Central, and South America

    2014-09-01

    De La Rocque et al. 2011) and their spread into higher elevations of Africa, Latin America , and Asia (Epstein 2001). Dengue fever and...denguehemorrhagic fever have resurgeddramatically in Latin America (Zell 2004). In North America ,West Nile virus has impacted signiÞcantly the health and welfare of...VECTOR CONTROL, PEST MANAGEMENT, RESISTANCE, REPELLENTS Field Evaluations of Topical Arthropod Repellents in North, Central , and South America KENDRA

  11. 7 CFR 319.56-25 - Papayas from Central America and Brazil.

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Papayas from Central America and Brazil. 319.56-25... § 319.56-25 Papayas from Central America and Brazil. The Solo type of papaya may be imported into the... shipment to the United States in one of the following locations: (1) Brazil: State of Espirito Santo; all...

  12. Microsatellite data suggest significant population structure and differentiation within the malaria vector Anopheles darlingi in Central and South America

    Achee Nicole L

    2008-03-01

    Full Text Available Abstract Background Anopheles darlingi is the most important malaria vector in the Neotropics. An understanding of A. darlingi's population structure and contemporary gene flow patterns is necessary if vector populations are to be successfully controlled. We assessed population genetic structure and levels of differentiation based on 1,376 samples from 31 localities throughout the Peruvian and Brazilian Amazon and Central America using 5–8 microsatellite loci. Results We found high levels of polymorphism for all of the Amazonian populations (mean RS = 7.62, mean HO = 0.742, and low levels for the Belize and Guatemalan populations (mean RS = 4.3, mean HO = 0.457. The Bayesian clustering analysis revealed five population clusters: northeastern Amazonian Brazil, southeastern and central Amazonian Brazil, western and central Amazonian Brazil, Peruvian Amazon, and the Central American populations. Within Central America there was low non-significant differentiation, except for between the populations separated by the Maya Mountains. Within Amazonia there was a moderate level of significant differentiation attributed to isolation by distance. Within Peru there was no significant population structure and low differentiation, and some evidence of a population expansion. The pairwise estimates of genetic differentiation between Central America and Amazonian populations were all very high and highly significant (FST = 0.1859 – 0.3901, P DA and FST distance-based trees illustrated the main division to be between Central America and Amazonia. Conclusion We detected a large amount of population structure in Amazonia, with three population clusters within Brazil and one including the Peru populations. The considerable differences in Ne among the populations may have contributed to the observed genetic differentiation. All of the data suggest that the primary division within A. darlingi corresponds to two white gene genotypes between Amazonia (genotype 1

  13. Active strike-slip faulting in El Salvador, Central America

    Corti, Giacomo; Carminati, Eugenio; Mazzarini, Francesco; Oziel Garcia, Marvyn

    2005-12-01

    Several major earthquakes have affected El Salvador, Central America, during the Past 100 yr as a consequence of oblique subduction of the Cocos plate under the Caribbean plate, which is partitioned between trench-orthogonal compression and strike-slip deformation parallel to the volcanic arc. Focal mechanisms and the distribution of the most destructive earthquakes, together with geomorphologic evidence, suggest that this transcurrent component of motion may be accommodated by a major strike-slip fault (El Salvador fault zone). We present field geological, structural, and geomorphological data collected in central El Salvador that allow the constraint of the kinematics and the Quaternary activity of this major seismogenic strike-slip fault system. Data suggest that the El Salvador fault zone consists of at least two main ˜E-W fault segments (San Vicente and Berlin segments), with associated secondary synthetic (WNW-ESE) and antithetic (NNW-SSE) Riedel shears and NW-SE tensional structures. The two main fault segments overlap in a dextral en echelon style with the formation of an intervening pull-apart basin. Our original geological and geomorphologic data suggest a late Pleistocene Holocene slip rate of ˜11 mm/yr along the Berlin segment, in contrast with low historical seismicity. The kinematics and rates of deformation suggested by our new data are consistent with models involving slip partitioning during oblique subduction, and support the notion that a trench-parallel component of motion between the Caribbean and Cocos plates is concentrated along E-W dextral strike-slip faults parallel to the volcanic arc.

  14. Soil conservation in Central America and Panama: current problems.

    Popenoe, H

    1976-06-01

    Soil conservation measures in Central America go back to the Maya civilization, in which terracing was employed. After the Spanish conquest, plowing, livestock raising, and the succession of social and political changes all contributed to accelerate erosion. Through the past few decades, awareness of the need for soil conservation has again increased; El Salvador and Costa Rica began efforts in that direction in 1943. For sometime, the use of machinery and chemical fertilizers has masked the loss of topsoil, but under recent increases in population pressures, soil conservation measures are gaining in importance. Important agents of erosion in the tropics are heavy seasonal rains at high elevations, alternating with long dry seasons; wind erosion; and landslides after saturation of the soil during prolonged rains. Modern machinery often hastens soil removal, as do also overgrazing, deforestation and vertical crop rows. Under the present energy crisis, human labor is becoming again a significant element in crop production, and soil conservation becomes thereby more feasible and more important.

  15. Managing weather and climate risks to agriculture in North America, Central America and the Caribbean

    Harlan D. Shannon

    2015-12-01

    Full Text Available In recent decades, numerous weather- and climate-related natural disasters have impacted North America, Central America, and the Caribbean, repeatedly demonstrating how vulnerable local agriculture is to extreme episodic events. Given this recent history, and expectations that the frequency and intensity of some episodic events will increase with climate change, it is becoming increasingly important for farmers to proactively manage weather and climate risks to agriculture to protect their livelihoods. Some farmers in this region already apply various strategies to help reduce weather and climate risks and uncertainties, including farming in multiple locations, diversifying crops and varieties, seeking alternative sources of income, and purchasing crop insurance. Such efforts often help farmers maintain a more stable income while also protecting and preserving the productivity of the land. Other farmers, however, have failed to implement basic risk management strategies despite the clear benefits. Reasons for these failures can be attributed to inadequate farmer education and training, a lack of tools to help facilitate the practical application of risk management concepts, and poor communications between the agrometeorological and farming communities. The agrometeorological community can help overcome these obstacles by building upon existing efforts that have successfully educated farmers about weather and climate risks to agriculture and have equipped farmers with the data, tools, and applications necessary to manage these risks. Farmer input is critical to preparing effective educational and training materials and developing user-friendly risk management tools. The agrometeorological community should solicit input from farmers regularly to ensure that farmers are obtaining the information necessary to effectively manage weather and climate risks to agriculture.

  16. Federacion de Universidades Privadas de America Central y Panama: Boletin Estadistico (Federation of Private Universities of Central America and Panama: Statistical Bulletin).

    Serrano, Jorge A.

    This statistical bulletin provides details on the universities belonging to the Federation of Private Universities of Central America and Panama (FUPAC): Central American University, Rafael Landivar University, Saint John's College, University of Santa Maria La Antigua, Jose Simeon Canas University, Doctor Mariano Galvez University, and the…

  17. Biofuels in Central America, a real potential for commercial production

    Garcia, O.L. (Regional Coordinator Energy and Environmental Partnership with Central America EEP (El Salvador))

    2007-07-01

    The purpose of this paper is to show the current capabilities of the Central American countries regarding the production of biofuels, and the real potential in increasing the volumes produced and the impacts that can be generated if a non sustainable policy is followed for achieving the targets of biofuel production. Due to the world oil price crisis, and the fact that Central American counties are fully dependant on oil imports (just Guatemala and Belize produce little amounts of oil), just to mention, in some countries the imports of oil is equivalent to the 40% of the total exports, the region started to look for massive production of biofuels, something that it is not new for us. The countries have started with programs for producing ethanol from sugar cane, because it is one of the most strongest industries in Central America and they have all the infrastructure and financial sources to develop this project. The ethanol is a biofuel that can be mixed with gasoline or a complete substitute. Another biofuel that is currently under develop, is the production of biodiesel, and the main source for it nowadays is the Palm oil, where Costa Rica, Honduras and Guatemala have already commercial productions of crude palm oil, but the principal use of it is for the food industry, but now it is under assessment for using part of it for biodiesel. EEP is now developing pilot programs for production of biodiesel from a native plant named Jatropha curcas, and up to now we have a commercial plantation in Guatemala, and we started as well in Honduras for start spreading this plantations. In El Salvador we installed a pilot processing plant for biodiesel that can be operated with multiple feed stock, such as Jatropha, palm oil, castor oil, vegetable used oil and others. Currently we have interesting and good results regarding the production of Jatropha, we have developed a methodology for its cropping, harvesting and processing. All the vehicles and equipment involved in the

  18. Economic opportunities and challenges posed by China for Mexico and Central America

    Dussel Peters, Enrique

    2005-01-01

    "This study offers a basis for understanding China's performance from a Latin American perspective, and stressing the massive economic opportunities and challenges, and particularly for Central America and Mexico. Moreover, the document assesses in detail the macroeconomic, trade and employment policy and institutional changes in China and its potential effects in Central America and Mexico. These effects are analyzed in the Chinese, Central American, Mexican and US market in general, but als...

  19. Stomach cancer burden in Central and South America.

    Sierra, Monica S; Cueva, Patricia; Bravo, Luis Eduardo; Forman, David

    2016-09-01

    Stomach cancer mortality rates in Central and South America (CSA) are among the highest in the world. We describe the current burden of stomach cancer in CSA. We obtained regional and national-level cancer incidence data from 48 population-based registries (13 countries) and nation-wide cancer deaths from WHO's mortality database (18 countries). We estimated world population age-standardized incidence (ASR) and mortality (ASMR) rates per 100,000 and estimated annual percent change to describe time trends. Stomach cancer was among the 5 most frequently diagnosed cancers and a leading cause of cancer mortality. Between CSA countries, incidence varied by 6-fold and mortality by 5-6-fold. Males had up to 3-times higher rates than females. From 2003 to 2007, the highest ASRs were in Chile, Costa Rica, Colombia, Ecuador, Brazil and Peru (males: 19.2-29.1, females: 9.7-15.1). The highest ASMRs were in Chilean, Costa Rican, Colombian and Guatemalan males (17.4-24.6) and in Guatemalan, Ecuadorian and Peruvian females (10.5-17.1). From 1997 to 2008, incidence declined by 4% per year in Brazil, Chile and Costa Rica; mortality declined by 3-4% in Costa Rica and Chile. 60-96% of all the cancer cases were unspecified in relation to gastric sub-site but, among those specified, non-cardia cancers occurred 2-13-times more frequently than cardia cancers. The variation in rates may reflect differences in the prevalence of Helicobacter pylori infection and other risk factors. High mortality may additionally reflect deficiencies in healthcare access. The high proportion of unspecified cases calls for improving cancer registration processes. Copyright © 2015 International Agency for Research on Cancer. Published by Elsevier Ltd.. All rights reserved.

  20. Prostate cancer burden in Central and South America.

    Sierra, Mónica S; Soerjomataram, Isabelle; Forman, David

    2016-09-01

    The incidence of prostate cancer has increased in Central and South America (CSA) in the last few decades. We describe the geographical patterns and trends of prostate cancer in CSA. We obtained regional and national-level cancer incidence data from 48 population-based registries in 13 countries and nation-wide cancer deaths from the WHO mortality database for 18 countries. We estimated world population age-standardized incidence (ASR) and mortality (ASMR) rates per 100,000 person-years for 2003-2007 and the estimated annual percent change (EAPC) to describe time trends. Prostate cancer was the most common cancer diagnosis and one of the leading causes of cancer deaths among males in most CSA countries. From 2003-2007, ASRs varied between countries (6-fold) and within countries (Brazil: 3-6-fold). French Guyana (147.1) and Brazil (91.4) had the highest ASRs whereas Mexico (28.9) and Cuba (24.3) had the lowest. ASMRs varied by 4-fold. Belize, Uruguay and Cuba (24.1-28.9) had the highest ASMRs while Peru, Nicaragua, and El Salvador (6.8-9.7) had the lowest. In Argentina, Brazil, Chile and Costa Rica prostate cancer incidence increased by 2.8-4.8% annually whereas mortality remained stable between 1997 and 2008. The geographic and temporal variation of prostate cancer rates observed in CSA may in part reflect differences in diagnostic and registration practices, healthcare access, treatment and death certification, and public awareness. The incidence of prostate cancer is expected to increase given recent early detection activities and increased public awareness; however, the impact of these factors on mortality remains to be elucidated. Copyright © 2016 International Agency for Research on Cancer. Published by Elsevier Ltd.. All rights reserved.

  1. Diabetes in South and Central America: an update.

    Aschner, Pablo; Aguilar-Salinas, Carlos; Aguirre, Loreto; Franco, Laercio; Gagliardino, Juan Jose; de Lapertosa, Sylvia Gorban; Seclen, Segundo; Vinocour, Mary

    2014-02-01

    The estimated population of the South and Central America (SACA) Region is 467.6 million and 64% is in the age range of 20-79 years but the population pyramid and age distribution are changing. The average prevalence of diabetes in the Region is 8.0% and is expected to reach 9.8% by the year 2035. Prevalence is much lower in rural settings than in urban and the differences attributed to lifestyle changes may be a target for intervention. The indigenous population is a particularly vulnerable group needing special attention. On average, 24% of the adult cases with diabetes are undiagnosed but in some countries this is still as high as 50%. Health expenditure due to diabetes in the Region is around 9% of the global total. Inadequate glycemic control, defined as HbA1c >7%, is a strong predictor of chronic complications which increase resource use in the Region and less than half of the patients enrolled in diabetes care programmes are at target. Fifty percent or more of the adult population is overweight/obese and around one third of the adult population has metabolic syndrome using regional cutoffs for waist circumference. The number of people with IGT is almost equal to those with diabetes presenting an additional challenge for prevention. Children with type 1 diabetes represent only 0.2% of the total population with diabetes but the incidence may be increasing. In many places they have limited access to insulin, and even when available, it is not used appropriately. The available epidemiological data provide the background to act in developing national diabetes programmes which integrate diabetes care with cardiovascular prevention and promote diabetes prevention as well. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  2. Outlook for modern cooking energy access in Central America

    2018-01-01

    The Central American nations of Guatemala, Honduras and Nicaragua are among the poorest in the Americas. While the fraction of population dependent on solid fuels has declined in these nations over the last 25 years, the number of people using them has risen. Here, we first assess current patterns of cooking energy use in these nations. We then apply a discrete model of household cooking choices and demand to simulate future pathways of clean cooking uptake and the outlook for achieving target 7.1 of the Sustainable Development Goals (SDG), which aims to ensure universal access to affordable, reliable and modern energy services by 2030. We find that by 2030, ensuing income growth is likely to enable 90% of urban populations in these nations to switch to using modern cooking energy services. However, without supporting policies, between 40% to 50% of rural Guatemalans and Hondurans, while over two-thirds of rural Nicaraguans, are likely to find clean fuels or stoves unaffordable in 2030. A targeted subsidy on modern fuels, like liquid petroleum gas (LPG), is the most effective policy mechanism we studied that could provide such support. A 50% subsidy policy on LPG targeted to the rural and urban poor population could, by 2030, make cooking with LPG affordable to an additional 7.3 million people in these countries. We estimate that such a policy would cost about $250 million per year and would have negligible greenhouse gas emissions impacts. Such a policy could also have significant health benefits, preventing about 8,890 premature deaths annually from reduced exposure to cooking-related household pollution in 2030. PMID:29883457

  3. Ground Motion Characteristics of Induced Earthquakes in Central North America

    Atkinson, G. M.; Assatourians, K.; Novakovic, M.

    2017-12-01

    The ground motion characteristics of induced earthquakes in central North America are investigated based on empirical analysis of a compiled database of 4,000,000 digital ground-motion records from events in induced-seismicity regions (especially Oklahoma). Ground-motion amplitudes are characterized non-parametrically by computing median amplitudes and their variability in magnitude-distance bins. We also use inversion techniques to solve for regional source, attenuation and site response effects. Ground motion models are used to interpret the observations and compare the source and attenuation attributes of induced earthquakes to those of their natural counterparts. Significant conclusions are that the stress parameter that controls the strength of high-frequency radiation is similar for induced earthquakes (depth of h 5 km) and shallow (h 5 km) natural earthquakes. By contrast, deeper natural earthquakes (h 10 km) have stronger high-frequency ground motions. At distances close to the epicenter, a greater focal depth (which increases distance from the hypocenter) counterbalances the effects of a larger stress parameter, resulting in motions of similar strength close to the epicenter, regardless of event depth. The felt effects of induced versus natural earthquakes are also investigated using USGS "Did You Feel It?" reports; 400,000 reports from natural events and 100,000 reports from induced events are considered. The felt reports confirm the trends that we expect based on ground-motion modeling, considering the offsetting effects of the stress parameter versus focal depth in controlling the strength of motions near the epicenter. Specifically, felt intensity for a given magnitude is similar near the epicenter, on average, for all event types and depths. At distances more than 10 km from the epicenter, deeper events are felt more strongly than shallow events. These ground-motion attributes imply that the induced-seismicity hazard is most critical for facilities in

  4. Some Recent USF Studies at Volcanoes in Central America

    McNutt, S. R.

    2014-12-01

    Scientists at the University of South Florida (USF) have been working in Central America for several decades. Efforts have focused on Physical Volcanology in Nicaragua, GPS in Costa Rica, and assessment of Geothermal projects in El Salvador, amongst others. Two years ago a Seismology Lab was established at USF. Personnel now include three Professors, a Post-Doc, and 4 graduate students. Seismic and GPS networks were installed at Telica Volcano, Nicaragua, in 2010 by Roman, LaFemina and colleagues. Data are recorded on site and recovered several times per year at this persistently restless volcano, which has rates of 5 to 1400 low frequency seismic events per day (Rodgers et al., submitted). Proposals have been submitted to install instruments on other Nicaraguan volcanoes, including seismometers, GPS, infrasound, and lightning sensors. This suite of instruments has proven to be very effective to study a range of volcanic processes. The proposals have not been successful to date (some are pending), and alternative funding sources are being explored. One interesting scientific issue is the presence of strong seasonal effects, specifically a pronounced rainy season and dry season and possible interaction between shallow volcanic processes and surface waters. We are also pursuing a variety of studies that are complementary to the instrumental efforts. One such study is examining volcanic earthquake swarms, with the focus to date on identifying diagnostics. One clear pattern is that peak rates often occur early in swarms, whereas the largest M event occurs late. Additional evidence suggests that the seismic source size grows systematically, especially for events with similar waveforms (families). Recognition of such patterns, linked to processes, may help to improve monitoring and better take advantage of instrumental data to reduce vulnerability from eruptions.

  5. Mapping Mangrove Density from Rapideye Data in Central America

    Son, Nguyen-Thanh; Chen, Chi-Farn; Chen, Cheng-Ru

    2017-06-01

    Mangrove forests provide a wide range of socioeconomic and ecological services for coastal communities. Extensive aquaculture development of mangrove waters in many developing countries has constantly ignored services of mangrove ecosystems, leading to unintended environmental consequences. Monitoring the current status and distribution of mangrove forests is deemed important for evaluating forest management strategies. This study aims to delineate the density distribution of mangrove forests in the Gulf of Fonseca, Central America with Rapideye data using the support vector machines (SVM). The data collected in 2012 for density classification of mangrove forests were processed based on four different band combination schemes: scheme-1 (bands 1-3, 5 excluding the red-edge band 4), scheme-2 (bands 1-5), scheme-3 (bands 1-3, 5 incorporating with the normalized difference vegetation index, NDVI), and scheme-4 (bands 1-3, 5 incorporating with the normalized difference red-edge index, NDRI). We also hypothesized if the obvious contribution of Rapideye red-edge band could improve the classification results. Three main steps of data processing were employed: (1), data pre-processing, (2) image classification, and (3) accuracy assessment to evaluate the contribution of red-edge band in terms of the accuracy of classification results across these four schemes. The classification maps compared with the ground reference data indicated the slightly higher accuracy level observed for schemes 2 and 4. The overall accuracies and Kappa coefficients were 97% and 0.95 for scheme-2 and 96.9% and 0.95 for scheme-4, respectively.

  6. Seismic swarms and fluid flow offshore Central America

    Dzierma, Yvonne; Thorwart, Martin; Hensen, Christian; Rabbel, Wolfgang; Wolf, Florian

    2010-05-01

    Offshore Nicaragua and Northern Costa Rica, the Cocos Plate subducts beneath the Caribbean Plate, carrying with it a large amount of fluids and volatiles. While some of these are set free at great depth beneath the volcanic arc, causing the extremely high water content observed in Nicaraguan mafic magmas (Carr et al., 2003; Kutterolf et al., 2007), some early dehydration reactions already release fluids from the subducting plate underneath the continental slope. Unlike in accretionary margins, where these fluids migrate up along the decollement towards the deformation front, fluid release at erosional margins seems to occur through fractures in the overriding plate (Ranero et al., 2008). Fluid seeps in this region have be observed at seafloor mounds, appearing as side-scan sonar backscatter anomalies or revealed by the presence of chemosynthetic communities (Sahling et al., 2008). In the framework of the General Research Area SFB 574 "Volatiles and Fluids in Subduction Zones", a network of 20 ocean-bottom-stations was deployed offshore Sta Elena Peninsula, Northern Costa Rica, from December 2005 to June 2006. Several distinct swarms of small earthquakes were observed at the seismic stations, which occurred clustered over a time period of several days and have very similar seismic waveforms. Since a correlation of fluid-release sites with the occurrence of sporadic seismic swarms would indicate that fluid migration and fracturing is the mechanism responsible for triggering the earthquake swarms, the events are re-analysed by double-difference localisation to enhance the resolution of the earthquake locations. The results are then considered to estimate the migration velocity and direction and compare the localisations with the known mound sites. Carr, M., Feigenson, M. D., Patino, L. C., and Walker, J. A., 2003: Volcanism and geochemistry in Central America: Progress and problems, in Eiler, J. (ed.), Inside the subduction factory, pp. 153-179, American Geophysical

  7. Drug Trafficking as a Lethal Regional Threat in Central America

    2011-12-16

    and Bolivia. 28 Panama It produces marijuana and serves as a critical transit country for all drugs coming from South America to the United...Colombian drug cartels. Paraguay This is a marijuana producing country. Its production probably never leaves South America; it is believed to supply...broad diversification of their products. The Mexican DTOs went through great efforts to establish laboratories for the cheap synthetic drugs in Mexico

  8. Agricultural drought assessment using remotely sensed data in Central America

    Nguyen, S. T.; Chen, C. F.; Chen, C. R.

    2017-12-01

    Central America is one of the world's regions most vulnerable to negative effects of agricultural drought due to impacts of climate change. Famers in the region have been confronting risks of crop damages and production losses due to intense droughts throughout the growing seasons. Drought information is thus deemed vital for policymakers to assess their crop management strategies in tackling issues of food insecurity in the region. This study aimed to delineate drought-prone areas associated with cropped areas from eight-day MODIS data in 2016 using the commonly used temperature dryness vegetation index (TVDI), calculated based on the land surface temperature (LST) and enhanced vegetation index (EVI) data. The advantages of MODIS data for agricultural drought monitoring at a national/regional scale are that it has the spatial resolution (500 m-1 km) and relatively high temporal resolution of eight days, but the data are often contaminated by clouds. Detecting and reconstructing the data under cloud-affected areas are generally a challenging task without any robust methods up to date. In this study, we reconstructed the eight-day MODIS EVI and LST data for agricultural drought assessment using machine-learning approaches. The reconstructed data were then used for drought assessment. The TVDI results verified with the soil moisture active passive (SMAP) data showed that the correlation coefficient values (r) obtained for the apante season (December-March) were between -0.4 to -0.8, while the values for the primera season (April-August) and postrera season (September-November) were in ranges of 0 to -0.6 and -0.2 to -0.7, respectively. The larger area of very dry soil moisture was generally observed during the dry season (December-April) and declined in the rainy season (May-November). The cropping areas affected by severe and moderate droughts observed for the primera season were respectively 11,846 km2 and 60,557 km2, while the values for the postera season were 14

  9. An Overview of School Dropout in Central America: Unresolved Issues and New Challenges for Education Progress

    Adelman, Melissa A.; Székely, Miguel

    2017-01-01

    School dropout is a growing concern in Central America, and in Latin America as a whole, because of its consequences for economic productivity, the inclusiveness of growth, social cohesion, and increasing youth risks. This paper utilizes more than two decades of household survey data to construct a systematic overview of school dropout at the…

  10. Genetic calibration of species diversity among North America's freshwater fishes.

    April, Julien; Mayden, Richard L; Hanner, Robert H; Bernatchez, Louis

    2011-06-28

    Freshwater ecosystems are being heavily exploited and degraded by human activities all over the world, including in North America, where fishes and fisheries are strongly affected. Despite centuries of taxonomic inquiry, problems inherent to species identification continue to hamper the conservation of North American freshwater fishes. Indeed, nearly 10% of species diversity is thought to remain undescribed. To provide an independent calibration of taxonomic uncertainty and to establish a more accessible molecular identification key for its application, we generated a standard reference library of mtDNA sequences (DNA barcodes) derived from expert-identified museum specimens for 752 North American freshwater fish species. This study demonstrates that 90% of known species can be delineated using barcodes. Moreover, it reveals numerous genetic discontinuities indicative of independently evolving lineages within described species, which points to the presence of morphologically cryptic diversity. From the 752 species analyzed, our survey flagged 138 named species that represent as many as 347 candidate species, which suggests a 28% increase in species diversity. In contrast, several species of parasitic and nonparasitic lampreys lack such discontinuity and may represent alternative life history strategies within single species. Therefore, it appears that the current North American freshwater fish taxonomy at the species level significantly conceals diversity in some groups, although artificially creating diversity in others. In addition to providing an easily accessible digital identification system, this study identifies 151 fish species for which taxonomic revision is required.

  11. The State of Federal Research Funding in Genetics as Reflected by Members of the Genetics Society of America.

    Rine, Jasper; Fagen, Adam P

    2015-08-01

    Scientific progress runs on the intellect, curiosity, and passion of its practitioners fueled by the research dollars of its sponsors. The concern over research funding in biology in general and genetics in particular led us to survey the membership of the Genetics Society of America for information about the federal support of genetics at the level of individual principal investigators. The results paint a mosaic of circumstances-some good, others not so good-that describes some of our present challenges with sufficient detail to suggest useful steps that could address the challenges. Copyright © 2015 by the Genetics Society of America.

  12. Legal Central Bank Independence and Inflation in Latin America During the 1990s

    Luis Ignacio Jácome

    2001-01-01

    This paper reviews central banks' legal reform in Latin America during the 1990s and discusses the status of central bank independence in the region. Based on this information, it builds a simplified index of central bank independence which, in addition to the commonly used criteria of political and economic independence, incorporates provisions of central banks' financial autonomy, accountability, and lender-of-last-resort. The paper finds a moderate negative correlation between increased ce...

  13. Genetics Home Reference: congenital central hypoventilation syndrome

    ... Kravis EM, Zhou L, Rand CM, Weese-Mayer DE. Congenital central hypoventilation syndrome: PHOX2B mutations and phenotype. Am J Respir Crit ... BA, Leurgans SE, Berry-Kravis EM, Weese-Mayer DE. Congenital central hypoventilation syndrome: PHOX2B genotype determines risk for sudden death. Pediatr ...

  14. Health outcomes among HIV-positive Latinos initiating antiretroviral therapy in North America versus Central and South America

    Cesar, Carina; Koethe, John R; Giganti, Mark J; Rebeiro, Peter; Althoff, Keri N; Napravnik, Sonia; Mayor, Angel; Grinsztejn, Beatriz; Wolff, Marcelo; Padgett, Denis; Sierra-Madero, Juan; Gotuzzo, Eduardo; Sterling, Timothy R; Willig, James; Levison, Julie; Kitahata, Mari; Rodriguez-Barradas, Maria C; Moore, Richard D; McGowan, Catherine; Shepherd, Bryan E; Cahn, Pedro

    2016-01-01

    Introduction Latinos living with HIV in the Americas share a common ethnic and cultural heritage. In North America, Latinos have a relatively high rate of new HIV infections but lower rates of engagement at all stages of the care continuum, whereas in Latin America antiretroviral therapy (ART) services continue to expand to meet treatment needs. In this analysis, we compare HIV treatment outcomes between Latinos receiving ART in North America versus Latin America. Methods HIV-positive adults initiating ART at Caribbean, Central and South America Network for HIV (CCASAnet) sites were compared to Latino patients (based on country of origin or ethnic identity) starting treatment at North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) sites in the United States and Canada between 2000 and 2011. Cox proportional hazards models compared mortality, treatment interruption, antiretroviral regimen change, virologic failure and loss to follow-up between cohorts. Results The study included 8400 CCASAnet and 2786 NA-ACCORD patients initiating ART. CCASAnet patients were younger (median 35 vs. 37 years), more likely to be female (27% vs. 20%) and had lower nadir CD4 count (median 148 vs. 195 cells/µL, p<0.001 for all). In multivariable analyses, CCASAnet patients had a higher risk of mortality after ART initiation (adjusted hazard ratio (AHR) 1.61; 95% confidence interval (CI): 1.32 to 1.96), particularly during the first year, but a lower hazard of treatment interruption (AHR: 0.46; 95% CI: 0.42 to 0.50), change to second-line ART (AHR: 0.56; 95% CI: 0.51 to 0.62) and virologic failure (AHR: 0.52; 95% CI: 0.48 to 0.57). Conclusions HIV-positive Latinos initiating ART in Latin America have greater continuity of treatment but are at higher risk of death than Latinos in North America. Factors underlying these differences, such as HIV testing, linkage and access to care, warrant further investigation. PMID:26996992

  15. Neurocysticercosos in South-Central America and the Indian Subcontinent: a comparative evaluation

    Gagandeep Singh

    1997-09-01

    Full Text Available Neurocysticercosis is an important public health problem in South-Central America and South Asia. A review of the differences in epidemiological and clinical attributes of cysticercosis and taeniasis in South Central America and India, respectively, is undertaken in the present communication. Intestinal taeniasis is hyperendemic in several American countries. In comparison, the prevalence of Taenia solium infestation is lower in India. The clinical manifestations in several American neurocysticercosis series comprise epilepsy, intracranial hypertension and meningeal - racemose cysticercosis, in roughly equal proportions. An overwhelming majority of the Indian subjects present with seizures. The commonest pathological substrate of the disorder in Indian patients is the solitary parenchymal degenerating cyst. The reasons for the predominance of solitary forms in India, and of multilesional forms in South Central America are discussed. The magnitude of Taenia solium infestation and the frequency of pork consumption in a given population appear to influence the quantum of cyst load in affected individuals.

  16. From violence to more violence in Central America

    Israel Medina

    2014-11-01

    Full Text Available Many Central American migrants flee their home country as a result of violence and threats from the criminal gangs. A large number of them also encounter the same type of violence that they are fleeing when on the migratory routes through Mexico.

  17. Do minimum wages reduce poverty? Evidence from Central America ...

    In all three countries, these multiple minimum wages are negotiated among representatives of the central government, labour unions and the chambers of commerce. Minimum wage legislation applies to all private-sector employees, but in all three countries a large part of the work force is self-employed or works as unpaid ...

  18. Development of Renewable Energies in the liberation of the energy market in Central America

    Rebollo, Jose; Puente, Margarita; Cabezas, Jose

    2000-01-01

    This paper presents the diagnostic of the current situation on renewable energy in Central America, including socio-economical situation, with economical index, supply and demand of energy and planning of wind resources. The experience of Europe in the promotion for the market of renewable energy, discussing the policies and cooperation between private sector and the government is included. A list of potential projects of renewable energy in each country of Central America based on biomass, hydro power, wind and other energy sources for power generation is presented

  19. Regulating human genetic research in Latin America: a race to the top or a race together?

    Rosario Isasi

    2016-05-01

    Full Text Available Balancing the therapeutic potential of genetic science with the adoption of policies that reflect social values has proven to be a formidable task for Latin American countries. This essay presents some reflections on human genetics research policy in Latin America and explores a path forward for policy development.

  20. Central America : Big Data in Action for Development

    World Bank

    2014-01-01

    This report stemmed from a World Bank pilot activity to explore the potential of big data to address development challenges in Central American countries. As part of this activity we collected and analyzed a number of examples of leveraging big data for development. Because of the growing interest in this topic this report makes available to a broader audience those examples as well as the...

  1. Medical genetic services in Latin America: report of a meeting of experts

    Penchaszadeh Víctor B

    1998-01-01

    Full Text Available During the Ninth International Congress of Human Genetics which was held in Rio de Janeiro, Brazil, from 16 to 18 August 1996, a group of experts under the coordination of the authors discussed at length the state of medical genetics in Latin America. The facts and ideas presented at the meeting, which was sponsored by the Human Genetics Program of the World Health Organization (WHO and the Maternal and Child Health Program of the Pan American Health Organization, are examined in this document under three broad headings. The first verses on the history and current status of medical genetics in selected Latin American countries. This is followed by a discussion of the general features of medical genetics in the Region and by a final section of recommendations for promoting medical genetics in Latin America.

  2. How does the North American Free Trade Agreement (NAFTA) affect Central America?

    Leamer, Edward E.; Guerra, Alfonso; Kaufman, Martin; Segura, Boris

    1995-01-01

    Most Central American economies experienced slower growth in the 1980s than in the 1960s and 1970s, trailing far behind the Asian Tigers. Contributing to slow growth were severe external shocks, sizable macroeconomic disturbances, and widespread political instability. The challenges Central America faces now may be even greater, conclude the authors, because of Mexican liberalization, continuing instability of the real exchange rate, low savings rates, and, finally, the North American Free Tr...

  3. CO2 emissions, energy usage, and output in Central America

    Apergis, Nicholas; Payne, James E.

    2009-01-01

    This study extends the recent work of Ang (2007) [Ang, J.B., 2007. CO 2 emissions, energy consumption, and output in France. Energy Policy 35, 4772-4778] in examining the causal relationship between carbon dioxide emissions, energy consumption, and output within a panel vector error correction model for six Central American countries over the period 1971-2004. In long-run equilibrium energy consumption has a positive and statistically significant impact on emissions while real output exhibits the inverted U-shape pattern associated with the Environmental Kuznets Curve (EKC) hypothesis. The short-run dynamics indicate unidirectional causality from energy consumption and real output, respectively, to emissions along with bidirectional causality between energy consumption and real output. In the long-run there appears to be bidirectional causality between energy consumption and emissions.

  4. Central America Regional Climate Change Program: Tools for Your Use

    Irwin, Dan; Irving, Bill; Yeager, Carey

    2006-01-01

    USAID/E-CAM and EGAT's Global Climate Change Team, in partnership with EPA, NASA, Oak Ridge National Lab, and the Central American Commission for Environment and Development (CCAD), have had a significant impact on the region's ability to monitor, mitigate, and adapt to environmental threats. Environmental decision-making tools and data are posted on a website (SERVIR: http://servir.nsstc.nasa.pov/home.html)that provides satellite and geographic data and maps to anybody with an Internet connection. The SERVIR program has been identified as the model for the Global Earth Observation System of Systems (GEOSS) - a major international effort to develop a 21st century system for environmental management and disaster response. In coordination with the USAID/EPA program, NASA has developed a GIs tool that enables countries to examine their forest cover and document changes on an annual basis. This information is used in calculating carbon emissions as part of greenhouse gas inventories, but also serves a valuable monitoring function. In addition, USAID/E-CAM and EGAT's Global Climate Change Team in collaboration with EPA are helping countries meet their obligations as signatories to the United Nations Framework Convention on Climate Change (UNFCCC). EPA is assisting Central American governments to improve the quality of their greenhouse gas emission inventories reported to the UNFCCC through the development of tools and improvements in data quality. New EPA tools developed include software to automatically calculate greenhouse gas emissions for the agricultural and forestry sector inventories, determine key sources of greenhouse gas emissions, and document institutional arrangements. Several of these tools are state of the art and are comparable to tools currently used in the U.S.

  5. Capacity-Building Programs Under the Dominican Republic-Central America-United States Free Trade Agreement (CAFTA-DR)

    The United States signed the Dominican Republic-Central America-United States Free Trade Agreement (CAFTA-DR) in August 2004 with five Central American countries (Costa Rica, El Salvador, Guatemala, Honduras, and Nicaragua) and the Dominican Republic.

  6. Post Doctorate Award on Central America and the Caribbean at St ...

    This grant will allow St Antony's College at the University of Oxford to establish a 2-year post doctoral position on Central America and the Caribbean under the leadership of Canadian historian, Margaret MacMillan. The position will be awarded to a scholar from the region, in keeping with IDRC's philosophy that developing ...

  7. Drug Cartels and Gangs in Mexico and Central America: A View through the Lens of Counterinsurgency

    2010-06-04

    organization. The demise of this long–standing dynasty began after the assassination of Pedro Joaquin Chamorro, leader of the Democratic Union of Liberation...describes Mexico and all of Central America as flawed democracies with the exception of Costa Rica, which is rated as a full democracy.36 The democratic

  8. "Central America in the World Economy of the 21st Century" phases ...

    Fernando Loayza

    on fiscal and taxation challenges of Central America economic integration. ..... second phase, supporting research studies by assignment was adopted along ..... Fees fluctuated between US$ 10,000 to 15,000 to cover the costs of two or three ...

  9. Fostering regional democracy through civic organisations: comparing EU mechanisms in Europe and Central America

    Sanchez Salgado, R.; Parthenay, K.

    2013-01-01

    This article compares the effects of the mechanisms of the European Union (EU) on the promotion of regional civic organisations, especially funding opportunities, in two regional settings (Central America and Europe). It is argued that the EU is exporting a specific model of relationships between

  10. A new genus and two new species of Tingidae (Heteroptera) from Central America.

    Montemayor, Sara I

    2008-04-01

    A new genus, Ceratotingis, distributed in Central America, is described to accommodate two new species, C. rafaeli from Panama and C. costarriquense from Costa Rica and to include Macrotingis zeteki from Panama. This paper includes descriptions of the new genus and its species, a redescription of C. zeteki, an identification key, and habitus photographs.

  11. Book review: Vetter, H. 2005. Terralog. Turtles of the World. Vol. 3. Central and South America

    2006-12-01

    Full Text Available Book review: Vetter, H. 2005. Terralog. Turtles of the World. Vol. 3. Central and South America/Schildkröten der Welt Band 3. Mittel- und Südamerika: 1-128, color pictures 606 + 9. Edition Chimaira, Frankfurt, Germany.ISBN 3-930612-82-8; 29.7 x 20.8 cm

  12. Planting the Seeds of a New Agriculture: Living with the Land in Central America.

    Adriance, Jim

    1995-01-01

    Central America's macroeconomics, land tenure patterns, and population growth are forcing small-scale farmers to alternatives based on farmer-to-farmer teaching and farming in concert with the environment. Discusses major schools of thought that have fueled this phenomenon, and how extension services and isolated groups are joining to form a…

  13. Post Doctorate Award on Central America and the Caribbean at St ...

    English · Français ... a 2-year post doctoral position on Central America and the Caribbean under the leadership of Canadian historian, Margaret MacMillan. ... Between 1965 and 2000, about 12% of the Caribbean labour force moved to ...

  14. Corporate good citizenship pays off in Central America.

    1974-07-22

    Fear of expropriation and increasing public scrutiny of the activities of multinational companies are forcing these companies to develop social programs in the countries where they operate. Frequently these programs are viewed as products of colonialism or as veiled attempts to dominate the nationals employed by these companies. The United Brands Company, which is involved in large scale banana production in several Central American countries, has adopted a program which seeks to reduce the paternalism which was associated with the operations of the United Fruit Company, the predecessor of the United Brands Company. A series of new programs emphasizing community self help projects were developed by a company-hired sociologist and initiated 4 years ago. In Panama, the projects were started by holding town meetings in which the citizens decided what projects to pursue. With company help the community has begun to build recreational and educational facilities and are also building new docks. The company is contributing $10 million annually to promote these projects. Other programs involve selling homes to workers for half the cost of constructing these homes and increasing efforts to put host country citizens into management positions. Home ownership is expected to stabilize the work force and increased opportunities for advancement are expected to increase productivity. Future plans include the construction of technical schools which will provide a pool of skilled technicians needed by the banana company.

  15. Burden of colorectal cancer in Central and South America.

    Sierra, Monica S; Forman, David

    2016-09-01

    The colorectal cancer (CRC) burden is increasing in Central and South American due to an ongoing transition towards higher levels of human development. We describe the burden of CRC in the region and review the current status of disease control. We obtained regional- and national-level incidence data from 48 population-based cancer registries in 13 countries, as well as cancer deaths from the WHO mortality database for 18 countries. We estimated world population age-standardized incidence (ASR) and mortality (ASMR) rates per 100,000 person-years for 2003-2007 and the estimated annual percentage change for 1997-2008. The CRC rate in males was 1-2 times higher than that in females. In 2003-2007, the highest ASRs were seen in Uruguayan, Brazilian and Argentinean males (25.2-34.2) and Uruguayan and Brazilian females (21.5-24.7), while El Salvador had the lowest ASR in both sexes (males: 1.5, females: 1.3). ASMRs were<10 for both sexes, except in Uruguay, Cuba and Argentina (10.0-17.7 and 11.3-12.0). CRC incidence is increasing in Chilean males. Most countries have national screening guidelines. Uruguay and Argentina have implemented national screening programs. Geographic variation in CRC and sex gaps may be explained by differences in the prevalence of obesity, physical inactivity, diet, smoking and alcohol consumption, early detection, and cancer registration practices. Establishing optimal CRC screening programs is challenging due to lack of healthcare access and coverage, funding, regional differences and inadequate infrastructure, and may not be feasible. Given the current status of CRC in the region, data generated by population-based cancer registries is crucial for cancer control planning. Copyright © 2015 International Agency for Research on Cancer. Published by Elsevier Ltd.. All rights reserved.

  16. Genetic calibration of species diversity among North America's freshwater fishes

    April, Julien; Mayden, Richard L.; Hanner, Robert H.; Bernatchez, Louis

    2011-01-01

    Freshwater ecosystems are being heavily exploited and degraded by human activities all over the world, including in North America, where fishes and fisheries are strongly affected. Despite centuries of taxonomic inquiry, problems inherent to species identification continue to hamper the conservation of North American freshwater fishes. Indeed, nearly 10% of species diversity is thought to remain undescribed. To provide an independent calibration of taxonomic uncertainty and to establish a mor...

  17. Hydrogeochemical investigation of six geothermal sites in Honduras, Central America

    Goff, F.E.; Truesdell, A.H.; Grigsby, C.O.; Janik, C.J.; Shevenell, L.A.; Paredes, J.R.; Gutierrez, J.W.; Trujillo, Jr.; Counce, D.A.

    1987-06-01

    We conducted detailed hydrogeochemical investigations at six geothermal sites in western Honduras: Azacualpa, El Olivar, Pavana, Platanares, Sambo Creek, and San Ignacio. None of the sites is associated with Quaternary silicic volcanism, although El Olivar lies adjacent to a small Quaternary basalt field and Pavana is part of a belt of hot spring activity parallel to and 35 km east of the Central American volcanic arc. None of the sites contains acid-sulfate waters indicative of vapor-dominated conditions. Thermal fluids are characterized by pH between 7 and 10, Cl<125 mg/l, HCO/sub 3/>Cl, SO/sub 4/greater than or equal toCl, Bless than or equal to17 mg/l, Liless than or equal to4 mg/l, and Asless than or equal to1.25 mg/l. Stable isotope analyses of the water show that recharge to the geothermal systems generally occurs from areas of higher elevation adjacent to the sites. Tritium contents of apparently undiluted thermal fluids range from 0 to 0.4 T.U., indicating residence times of fluids in the systems of more than 500 y. Various geochemical indicators show that mixing of hot and cold end-member fluids occurs in the system at Platanares and, to a lesser degree, in the systems at San Ignacio and Azacualpa. No mixing is apparent in the fluids discharging at Pavana, Sambo Creek, or El Olivar. Boiling is the dominant process responsible for subtle geochemical variations at Azacualpa and, possibly, San Ignacio. Our best estimates of subsurface reservoir temperatures are 225/sup 0/C at Platanares, 190/sup 0/C at San Ignacio, 185/sup 0/C at Azacualpa, 155/sup 0/C at Sambo Creek, 150/sup 0/C at Pavana, and 120/sup 0/C at El Olivar. The estimated power output of the three hottest sites is 45 thermal megawatts at Platanares, 14 thermal megawatts at San Ignacio, and 13 thermal megawatts at Azacualpa.

  18. A climatology of low level wind regimes over Central America using a weather type classification approach.

    Fernán eSáenz

    2015-04-01

    Full Text Available Based on the potential of the weather types classification method to study synoptic features, this study proposes the application of such methodology for the identification of the main large scale patterns related with weather in Central America. Using ERA Interim low-level winds in a domain that encompasses the intra-Americas sea, the eastern tropical Pacific, southern North America, Central America and northern South America; the K-means clustering algorithm was applied to find recurrent regimes of low-level winds. Eleven regimes were identified and good coherency between the results and known features of regional circulation was found. It was determined that the main large scale patterns can be either locally forced or a response to tropical-extratropical interactions. Moreover, the local forcing dominates the summer regimes whereas mid latitude interactions lead winter regimes. The study of the relationship between the large scale patterns and regional precipitation shows that winter regimes are related with the Caribbean-Pacific precipitation seesaw. Summer regimes, on the other hand, enhance the Caribbean-Pacific precipitation contrasting distribution as a function of the dominant regimes. A strong influence of ENSO on the frequency and duration of the regimes was found. It was determined that the specific effect of ENSO on the regimes depends on whether the circulation is locally forced or lead by the interaction between the tropics and the mid-latitudes. The study of the cold surges using the information of the identified regimes revealed that three regimes are linkable with the occurrence of cold surges that affect Central America and its precipitation. As the winter regimes are largely dependent of mid-latitude interaction with the tropics, the effect that ENSO has on the Jet Stream is reflected in the winter regimes. An automated analysis of large scale conditions based on reanalysis and/or model data seems useful for both dynamical

  19. Mapping agricultural landscapes and characterizing adaptive capacity in Central America

    Holland, M. B.; Imbach, P. A.; Bouroncle, C.; Donatti, C.; Leguia, E.; Martinez, M.; Medellin, C.; Saborio-Rodriguez, M.; Shamer, S.; Zamora, J.

    2013-12-01

    One of the key challenges in developing adaptation strategies for smallholder farmers in developing countries is that of a data-poor environment, where spatially-explicit information about where the most vulnerable smallholder communities are located is lacking. Developing countries tend to lack consistent and reliable maps on agricultural land use, and have limited information available on smallholder adaptive capacity. We developed a novel participatory and expert mapping process to overcome these barriers and develop detailed national-scale maps that allow for a characterization of unique agricultural landscapes based on profiles of adaptive capacity for smallholder agriculture in each area. This research focuses specifically on the Central American nations of Costa Rica, Guatemala, and Honduras, where our focus is on coffee and basic grains as the two main cropping systems. Here we present the methodology and results of a series of in-depth interviews and participatory mapping sessions with experts working within the broader agricultural sector in each country. We held individual interviews and mapping sessions with approximately thirty experts from each country, and used a detailed survey instrument for each mapping session to both spatially identify distinct agricultural landscapes, and to further characterize each area based on specific farm practices and social context. The survey also included a series of questions to help us assess the relative adaptive capacity of smallholder agriculture within each landscape. After all expert mapping sessions were completed in each country we convened an expert group to assist in both validating and refining the set of landscapes already defined. We developed a characterization of adaptive capacity by aggregating indicators into main assets-based criteria (e.g. land tenure, access to credit, access to technical assistance, sustainable farm practices) derived from further expert weighting of indicators through an online

  20. Peripartum Cardiomyopathy: Moving Towards a More Central Role of Genetics#

    Cemin, Roberto; Janardhanan, Rajesh; Donazzan, Luca; Daves, Massimo

    2013-01-01

    Peripartum cardiomyopathy (PCM) is a relatively rare disease with potentially devasting consequences requiring prompt identification and correct treatment. Overall prognosis is good in majority of the cases, although some patients may progress to irreversible heart failure. Early diagnosis is important and effective treatment reduces mortality rates and increases the chance of complete recovery of ventricular systolic function. The aetiology and pathogenesis seems to be multifactorial and poorly understood, with the available literature rather conflicting. In recent years, there has been increased interest in the role played by genetic predisposition in the development of PCM. It probably develops as a result of a complex interaction of pregnancy-associated factors and genetic factors and recently there have been many observations pointing out the central role played by a genetic predisposition. The direct and indirect observations on genetic susceptibility may offer new insights into the pathogenesis of PCM. However, larger studies are needed before advising routine genetic testing in these patients. PMID:23909634

  1. A five-century sedimentary geochronology of biomass burning in Nicaragua and Central America

    Suman, D.O.

    1991-01-01

    In spite of the extensive use of fire as an agricultural agent in Central America today, little is known of its history of biomass burning or agriculture. As an indicator of the burning practices on the adjacent land, a sedimentary record of carbonized particles sheds light on the trends in frequency and areal extent of biomass burning. This research focuses on a sediment core recovered from an anoxic site in the Pacific Ocean adjacent to the Central American Isthmus and reports a five-century record of charcoal deposition. The research illustrates that biomass burning has been an important ecological factor in the Pacific watershed of Central America at least during the past five centuries. Fluxes of charcoal have generally decreased toward the present suggesting a reduction in the charcoal source function. Perhaps, five centuries ago, the frequency of biomass burning was greater than it is today, larger areas were burned, or biomass per unit area of burned grassland was greater. The major type of biomass burned throughout this five-century period has been grass, as opposed to woods, indicating that any major deforestation of the Pacific watershed of Central America occurred prior to the Conquest

  2. The implications of trade liberalization for diet and health: a case study from Central America.

    Thow, Anne Marie; Hawkes, Corinna

    2009-07-28

    Central America has undergone extensive trade liberalization over the past two decades, and has recently signed a Free Trade Agreement with the United States. The region is also experiencing a dual burden of malnutrition with the growth of dietary patterns associated with the global 'nutrition transition'. This study describes the relationship between trade liberalization policies and food imports and availability, and draws implications for diet and health, using Central America as a case study region. Changes in tariff and non-tariff barriers for each country were documented, and compared with time-series graphs of import, production and availability data to show the outcome of changes in trade policy in relation to food imports and food availability. Changes in trade policy in Central America have directly affected food imports and availability via three avenues. First, the lowering of trade barriers has promoted availability by facilitating higher imports of a wide range of foods. Second, trade liberalization has affected food availability through promoting domestic meat production. Third, reductions in barriers to investment appear to be critical in expansion of processed food markets. This suggests that changes in trade policies have facilitated rising availability and consumption of meat, dairy products, processed foods and temperate (imported fruits) in Central America. This study indicates that the policies of trade liberalization in Central American countries over the past two decades, particularly in relation to the United States, have implications for health in the region. Specifically, they have been a factor in facilitating the "nutrition transition", which is associated with rising rates of obesity and chronic diseases such as cardiovascular disease and cancer. Given the significant cost of chronic disease for the health care system, individuals and the wider community, it is critical that preventive health measures address such upstream determinants

  3. Medicinal plants used to treat snakebite in Central America: Review and assessment of scientific evidence.

    Giovannini, Peter; Howes, Melanie-Jayne R

    2017-03-06

    Every year between 1.2 and 5.5 million people worldwide are victims of snakebites, with about 400,000 left permanently injured. In Central America an estimated 5500 snakebite cases are reported by health centres, but this is likely to be an underestimate due to unreported cases in rural regions. The aim of this study is to review the medicinal plants used traditionally to treat snakebites in seven Central American countries: Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua and Panama. A literature search was performed on published primary data on medicinal plants of Central America and those specifically pertaining to use against snakebites. Plant use reports for traditional snakebite remedies identified in primary sources were extracted and entered in a database, with data analysed in terms of the most frequent numbers of use reports. The scientific evidence that might support the local uses of the most frequently reported species was also examined. A total of 260 independent plant use reports were recorded in the 34 sources included in this review, encompassing 208 species used to treat snakebite in Central America. Only nine species were reported in at least three studies: Cissampelos pareira L., Piper amalago L., Aristolochia trilobata L., Sansevieria hyacinthoides (L.) Druce, Strychnos panamensis Seem., Dorstenia contrajerva L., Scoparia dulcis L., Hamelia patens Jacq., and Simaba cedron Planch. Genera with the highest number of species used to treat snakebite were Piper, Aristolochia, Hamelia, Ipomoea, Passiflora and Peperomia. The extent of the scientific evidence available to understand any pharmacological basis for their use against snakebites varied between different plant species. At least 208 plant species are traditionally used to treat snakebite in Central America but there is a lack of clinical research to evaluate their efficacy and safety. Available pharmacological data suggest different plant species may target different symptoms of

  4. The implications of trade liberalization for diet and health: a case study from Central America

    Hawkes Corinna

    2009-07-01

    Full Text Available Abstract Background Central America has undergone extensive trade liberalization over the past two decades, and has recently signed a Free Trade Agreement with the United States. The region is also experiencing a dual burden of malnutrition with the growth of dietary patterns associated with the global 'nutrition transition'. This study describes the relationship between trade liberalization policies and food imports and availability, and draws implications for diet and health, using Central America as a case study region. Methods Changes in tariff and non-tariff barriers for each country were documented, and compared with time-series graphs of import, production and availability data to show the outcome of changes in trade policy in relation to food imports and food availability. Results Changes in trade policy in Central America have directly affected food imports and availability via three avenues. First, the lowering of trade barriers has promoted availability by facilitating higher imports of a wide range of foods. Second, trade liberalization has affected food availability through promoting domestic meat production. Third, reductions in barriers to investment appear to be critical in expansion of processed food markets. This suggests that changes in trade policies have facilitated rising availability and consumption of meat, dairy products, processed foods and temperate (imported fruits in Central America. Conclusion This study indicates that the policies of trade liberalization in Central American countries over the past two decades, particularly in relation to the United States, have implications for health in the region. Specifically, they have been a factor in facilitating the "nutrition transition", which is associated with rising rates of obesity and chronic diseases such as cardiovascular disease and cancer. Given the significant cost of chronic disease for the health care system, individuals and the wider community, it is critical

  5. Invasion genetics of emerald ash borer in North America

    Alicia M. Bray; Leah S. Bauer; Robert A. Haack; Therese Poland; James J. Smith

    2006-01-01

    Emerald ash borer (EAB) was first detected in Michigan and Canada in 2002. Efforts to eradicate this destructive pest by federal and state regulatory agencies continue. Knowledge of EAB genetics will be useful in understanding the invasion dynamics of the beetle and to help identify geographic localities of potential biocontrol agents.

  6. Central Ukraine Uranium Province: The genetic model

    Emetz, A.; Cuney, M.

    2014-01-01

    Ukraine produces ~1,100 t U per year from the Michurinske, Centralne, Novokostantynivske and Vatutinske U deposits in the Kirovograd U district of the Central Ukraine Uranium Province (CUUP) consisting of about 20 deposits and numerous showings related to ~1.8 Ga sodium metasomatites developed in the Lower Paleoproterozoic granite-gneiss and iron formations of the Ingul Megablock of the Ukrainian Shield. Two deposits (the Zhovta Richka and Pervomayske) were mined out tens kilometers eastward in iron formations of the Kryvy Rig – Kremenchug mining district. Nametasomatite fields with scarce sub-economical U-mineralization were revealed by geophysical (magnetometry and gravimetry) and drilling programs northward in granitised gneisses around the younger Korsun-Novomyrgorod rapakivi pluton consisting of A2-type within plate granitoids which were emplaced during decompression melting at ~1.75 Ga. The present work aims to demonstrate structural and geochemical factors related to Na-metasomatism, and to mark out geochemical and tectonical parameters which were favorable for U-accumulation using data on deep seismic survey, geological structure analysis, and mineralogical and geochemical investigations of metasomatites. In the Ingul Megablock, Na-metasomatites occur along shear fault zones mostly oriented N-S. Metasomatites form complicate systems of plate- and lens-like bodies of aegirine-riebeckite albitites surrounded by dequartzified host rocks. Elemental alteration during Na-metasomatism demonstrates simple exchange of Si, K, Rb, Ba and Cs by Na, Ca, and locally V and U. δ 18 O H 2 O (300-400ºC) for albitizing hydrothermal solutions is near “zero”, typically for surficial water. These data suggest host rock interaction with hot marine waters. Persistent Na-metasomatic alterations extend along major tectonic faults for several kilometres with variable thicknesses reaching some hundreds meters in the zones of intense brecciation developed in the places of fault

  7. Mineral deposits of Central America, with a section on manganese deposits of Panama

    Roberts, Ralph Jackson; Irving, Earl Montgomery; Simons, F.S.

    1957-01-01

    The mineral deposits of Central America were studied between 1942 and 1945, in cooperation with the United States Department of State and the Foreign Economic Administration. Emphasis was originally placed on the study of strategic-mineral deposits, especially of antimony, chromite, manganese, quartz, and mica, but deposits of other minerals that offered promise of significant future production were also studied. A brief appraisal of the base-metal deposits was made, and deposits of iron ore in Honduras and of lead and zinc ores in Guatemala were mapped. In addition, studies were made of the regional geology of some areas, data were collected from many sources, and a new map of the geology of Central America was compiled.

  8. Neoliberal Forms of Capital and The Rise of Social Movement Partyism in Central America

    Paul Almeida

    2015-08-01

    Full Text Available Historical shifts in global economic formations shape the strategies of resistance movements in the global South. Neoliberal forms of economic development over the past thirty years in Central America have weakened traditional actors sponsoring popular mobilization such as labor unions and rural cooperatives. At the same time, the free market reforms produced new threats to economic livelihood and well-being throughout the region. The neoliberal measures that have generated the greatest levels of mass discontent include rising prices, privatization, labor flexibility laws, mining projects, and free trade. This article analyzes the role of emerging anti-neoliberal political parties in alliance with popular movements in Central America. Countries with already existing strong anti-systemic parties in the initial phases of the global turn to neoliberalism in the late twentieth century resulted in more efficacious manifestations of social movement partyism in the twenty-first century resisting free market globalization.

  9. The Previously Undetected Presence of Culex restuans (Diptera: Culicidae) in Central America, with Notes on Identification

    1988-01-01

    geografica actualizada. Rev. Inv. Salud Publica (Mexico) 33: 11 I - 125. Heinemann, S.J. and J.N. Belkin. 1977. Collection records of the project...Mosquitoes of Middle America” 8. Central America: Belize (BH), Guatemala (GUA), El Salvador ( SAL ), Honduras (HON), Nicaragua (NI, NIC). Mosq. Syst...Culicidae). Ill. Nat. Hist. Surv. Biol. Notes 52, 50 pp. Vargas, L. 1956. Especies y distribucidn de mosquitos mexicanos no anofelinos. Rev. Instit. de

  10. Sovereignty under siege: drug trafficking and state capacity in the Caribbean and Central America

    King, Ryan Thomas

    2016-01-01

    Approved for public release; distribution is unlimited Drug trafficking organizations have increased their prominence throughout the Caribbean and Central America. These organizations undermine the rule of law, increase levels of violence and corruption, and hamper development, all of which can weaken a state. Weak or failing states become domestic and regional burdens that spill over into neighboring countries and cause secondary and tertiary problems. This thesis examines causes for diff...

  11. A key to the Mexican and Central America Genera of Anthonomini (Curculionidae, Curculioninae)

    Hernández, Macotulio Soto; Jones, Robert W.; Castillo, Pedro Reyes

    2013-01-01

    Abstract Presently the only keys available for identification of genera of Anthonomini are limited to those of the United States of America and Canada. A dichotomous key is presented to identify all genera of Mexican and Central American Anthonomini. Previous keys do not include the genera Achia, Botanebius, Loncophorus, Loncophorellus and Melexerus. A brief synopsis is given for each genus and photographs of representative species are included. PMID:23717181

  12. [Musculoskeletal pain in Central American workers: results of the First Survey on Working Conditions and Health in Central America].

    Rojas, Marianela; Gimeno, David; Vargas-Prada, Sergio; Benavides, Fernando G

    2015-08-01

    Examine the prevalence of musculoskeletal pain (MSP) in the six Spanish-speaking countries of Central America using a single standardized instrument, the First Survey on Working Conditions and Health in Central America in workers from all manual and non-manual labor sectors, using social security coverage as an indicator of formal versus informal employment. The workers (n = 12 024) were surveyed in their homes. The age-adjusted prevalence of MSP during the previous month was calculated for pain in the back (upper, or cervical; middle, or thoracic; and lower, or lumbar) and arm joints (shoulder, elbow, and wrist). Prevalence was estimated by sex, occupation (manual or non-manual), economic sector (agriculture, industry, or services), and social security coverage. Poisson regression models were used to calculate the prevalence rates and 95% confidence intervals, with stratification by country and anatomical site. By sites, the age-adjusted prevalence of cervical-dorsal MSP was the highest, especially in El Salvador (47.8%) and Nicaragua (45.9%), and lumbar MSP was less prevalent, especially in Panama (12.8%) and Guatemala (14.8%). After additional adjustments, the prevalence of MSP was higher in women and manual workers for all the sites and in all the countries. There were no differences in MSP in terms of social security coverage or sector of economic activity. The high prevalence of MSP in Central America, regardless of sector of activity or social security coverage, indicates that the prevention of MSP should be a priority in occupational health programs in low- and middle-income countries, especially for women and manual workers.

  13. Prevalence of metabolic syndrome in Central America: a cross-sectional population-based study

    Roy A. Wong-McClure

    2015-09-01

    Full Text Available OBJECTIVE: To report the prevalence of metabolic syndrome (MetS as found by the Central American Diabetes Initiative (CAMDI study for five major Central American populations: Belize (national; Costa Rica (San José; Guatemala (Guatemala City; Honduras (Tegucigalpa; and Nicaragua (Managua. METHODS: Study data on 6 185 adults aged 20 years or older with anthropometric and laboratory determination of MetS from population-based surveys were analyzed. Overall, the survey response rate was 82.0%. MetS prevalence was determined according to criteria from the Adult Treatment Panel III of the National Cholesterol Education Program. The study's protocol was reviewed and approved by the bioethical committee of each country studied. RESULTS: The overall standardized prevalence of MetS in the Central American region was 30.3% (95% confidence interval (CI: 27.1-33.4. There was wide variability by gender and work conditions, with higher prevalence among females and unpaid workers. The standardized percentage of the population free of any component of MetS was lowest in Costa Rica (9.0%; CI: 6.5-11.4 and highest in Honduras (21.1%; CI: 16.4-25.9. CONCLUSIONS: Overall prevalence of MetS in Central America is high. Strengthening surveillance of chronic diseases and establishing effective programs for preventing cardiovascular diseases might reduce the risk of MetS in Central America.

  14. An analysis of Central America and Eastern Europe Revealed Comparative Advantages

    Mauricio Garita Gutierrez

    2014-03-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0pt 5.4pt 0pt 5.4pt; mso-para-margin:0pt; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} The present study applies the revealed comparative advantages through the Balassa Index to determine the comparative advantages, disadvantages, and intra-product commerce tendencies between Central America and Eastern Europe with the purpose of determining the possibility of a free trade agreement for Central America. The approach of the study is through the connection between the European Economic Union and the Central American Common market, which shares a common background and relates them to research of Bela Balassa (1965 to determine how commerce between Central America and Eastern Europe has performed and the possibilities of growth that this commerce has through a free trade agreement. The study demonstrates the importance of analyzing competitive advantages. This paper presents the difference in competitive advantage between Eastern Europe and Central American establishing the benefits when negotiating a free trade agreement between both economic blocks. Therefore, analyzing and negotiating between products of competitive advantages may lead to a more sustainable economic growth.

  15. [Trends in the urbanization process in Central America in the 1980's].

    Lungo Ucles, M

    1990-01-01

    In the 1980s, urbanization in Central America was increasing compared to the three previous decades. By 1990, the urban population reached 42% in Guatemala, 44% in El Salvador, 43% in Honduras, 59% in Nicaragua, 53% in Costa Rica, and 54% in Panama. The urban population increased mostly in the largest cities, in contrast to Latin America, where secondary cities grew fastest. This trend was particularly true in Managua and San Salvador because of the military conflicts. The only exception was Honduras, where the second city underwent stronger growth. The urban population comprised 51.7% women and 48.3% men in Central America. The segregation and polarization of social classes was also increasing because of increased poverty and unemployment during the 1980s. This was partly caused by the increasing privatization of public services, decentralization, and the reinforcement of local governments, which all ensued from the structural readjustment programs of the International Monetary Fund. This neoliberal model of economic development in the short run resulted in increased poverty and unemployment for the urban populations. In 1982, the informal sector represented 29% of the total employment in Central America, and its share reached 40% in Managua and San Salvador. Urban unemployment increased from 2.2% in 1980 to 12% in 1988 in Guatemala; from 8.8% to 13.1% in Honduras; and from 10.4% to 20.8% in Panama. In the political arena, the process of democratization was underway, with civil presidents taking power and promoting privatization and deregulation of the economy. There was a close relationship between the urban social structure, the economy, and politics in the region. In Costa Rica, during the Arias administration between 1986 and 1990, a program was implemented creating 80,000 new homes, and in El Salvador there was an increasing demand to find a negotiated solution to the military conflict. These new political and economic perspectives could lead to genuine

  16. Ethical issues in genetics and public health in Latin America with a focus on Argentina.

    Penchaszadeh, Victor B

    2015-07-01

    This paper reviews the health situation and developments in medical genetics and bioethics in Latin America, with a focus on Argentina. The region is the most inequitable in the world, with an average Gini Index of 52.5 and 25 % of the population living in poverty. Health expenditures are low and health systems are fragmented and privatised, with curtailed governmental responsibility and regulation. Health-care decision making is mostly in the hands of private insurance corporations and the medical-industrial complex, so that what is (or is not) covered by health plans is arbitrary and determined by the market and not by population health needs. This inequity and the lack of meaningful governmental intervention in the provision of health care, including genetic services, are at the heart of the bioethical dilemmas in Latin America. It is not surprising, therefore, that bioethics in the region has developed an approach grounded in social justice, equity and human rights as guiding principles, in contrast to the individualism espoused by Anglo-Saxon bioethics. The main ethical issues identified in genetics in Latin America are (1) inequity in access to genetic services, particularly in prenatal diagnosis, (2) genetic discrimination and (3) the lack of adherence to internationally accepted requisites of clinical validity and utility for diagnostic and predictive genetic testing. In this context, there is a risk that the impressive advances in genetics/genomics occurring in developed countries may fail to improve the public's health and deepen inequity, with the implementation of expensive genetic technologies of unproven validity.

  17. Detailed genetic structure of European bitterling populations in Central Europe

    Veronika Bartáková

    2015-11-01

    Full Text Available The European bitterling (Rhodeus amarus is a small cyprinid fish whose populations declined markedly between 1950 and 1980. However, its range currently expands, partly due to human-assisted introductions. We determined the genetic variability and detailed spatial structure among bitterling populations in Central Europe and tested alternative hypotheses about colonization of this area. Twelve polymorphic microsatellite loci on a large sample of 688 individuals had been used to analyse genetic variability and population structure. Samples originated from 27 localities with emphasis on area of the Czech Republic where three major sea drainages (Black, Baltic, and Northern Sea meet. Highly variable level of intrapopulation genetic variability had generally been detected and a recent decrease in numbers (“bottleneck” had been indicated by genetic data among six populations. High level of interpopulation differentiation was identified even within the basins. There was a significant role of genetic drift and indications of low dispersal ability of R. amarus. Surprisingly, the Odra River was inhabited by two distinct populations without any genetic signatures of a secondary contact. Czech part of the Odra (Baltic basin was colonized from the Danubian refugium (similarly to adjacent Danubian basin rivers including the Morava, while Polish part of the Odra was genetically similar to the populations in the Vistula River (Baltic basin, that has been colonized by a different (Eastern phylogeographic lineage of R. amarus. Most Czech R. amarus populations were colonized from the Danubian refugium, suggesting potential for a human-mediated colonization of the Odra or Elbe Rivers by R. amarus. One Elbe basin population was genetically mixed from the two (Danubian and Eastern phylogeographic lineages. In general the Czech populations of R. amarus were genetically stable except for a single population which has probably been recently introduced. This research

  18. Different educational glances in two pedagogical congresses : Cuba (1884 and Central America (1893

    Amalia Nivón Bolán

    2014-12-01

    Full Text Available The 19th Century pedagogical congresses carried out in Cuba and Central America were led by teachers and officials involved in the educational policy of primary education, and aware of the need to adjust the education’s foundation in order to react to the moment’s reality. This piece analyses the special conditions in Cuba and Central America that cause the reform of the primary education grounds that prevailed in schools during the Colony in the 18th and 19th Centuries. It also describes the protagonists in the educational practice elite that influenced the restruturing of the school system, knowledge and learning techniques, as well as the teachers’ educational or occupational profile. In addition, it outlines the economic circumstances and the political view of the groups of intellectuals trained in a context that inherited the legacy of the colonial conditions of racism and defense of agricultural and industrial work, and defined by abolitionist and pro-independence struggles.  The study was conducted from the UNESCO Memory of the First Central Pedagogical Congress and current research that relate to the Cuban Congress 1884, to identify educational activities and careers of influential intellectuals in shaping Cuban and Central American educational systems at sundown nineteenth century.

  19. Scorpionism in Central America, with special reference to the case of Panama

    A Borges

    2012-01-01

    Full Text Available Scorpionism in the Americas occurs mainly in Mexico, northern South America and southeast Brazil. This article reviews the local scorpion fauna, available health statistics, and the literature to assess scorpionism in Central America. Notwithstanding its high toxicity in Mexico, most scorpion sting cases in Guatemala, Belize, El Salvador, Nicaragua, and Costa Rica are produced by species in the genus Centruroides that are only mildly toxic to humans despite the existence of ion channel-active toxins in their venoms. Regional morbidity is low with the exception of Panama, where an incidence of 52 cases per 100,000 inhabitants was recorded for 2007, with 28 deaths from 1998 to 2006. Taxa belonging to the genus Tityus (also present in the Atlantic coast of Costa Rica are responsible for fatalities in Panama, with Tityus pachyurus being the most important species medically. Most Tityus species inhabiting Panama are also found in northern South America from which they probably migrated upon closure of the Panamanian isthmus in the Miocene era. Incorporation of Panama as part of the northern South American endemic area of scorpionism is thereby suggested based on the incidence of these accidents and the geographical distribution of Panamanian Tityus species.

  20. Genetic distinctions between autoimmune hepatitis in Italy and North America.

    Muratori, Paolo; Czaja, Albert-J; Muratori, Luigi; Pappas, Georgios; Maccariello, Silvana; Cassani, Fabio; Granito, Alessandro; Ferrari, Rodolfo; Mantovani, Vilma; Lenzi, Marco; Bianchi, Francesco-B

    2005-03-28

    Our goals were to analyze the known genetic predispositions for autoimmune hepatitis (AIH) in AIH Italian population and to compare them with North American counterparts. Human leukocyte antigens (HLA) B8, C7, DR3, DR4, DR7, DR11, DR13, DQ2 and the B8-DR3-DQ2 phenotype were determined by microlymphocytotoxicity and polymerase chain reaction in 74 Italian patients (57 with type 1 and 17 with type 2 AIH) and 149 North American patients with type 1 AIH, and in adequate controls. B8-DR3-DQ2 occurred more frequently in Italian patients with type 1 AIH than in Italian controls (30% vs 7%, P<0.0001), but less frequently than in North American counterparts (30% vs 48%, P = 0.02). DR4 occurred less frequently in Italian patients with type 1 AIH (23% vs 43%, P = 0.01) and in controls (16% vs 34%, P = 0.0003) than in North American counterparts. No differences were found in alleles' frequency between type 1 and type 2 Italian AIH patients. DR11 had a frequency lower in type 1 Italian AIH patients than controls (17% vs 35%, P = 0.01). HLA DR4 is not associated with AIH in Italy. The known HLA risk factors for AIH occur similarly in Italian patients with type 1 and type 2 AIH, and they are less frequent than in North American patients. B8-DR3-DQ2 is the predominant phenotype of type 1 AIH also in Italy, and HLA DR11 may be a regionally distinctive protective factor against type 1 AIH.

  1. A spatio-temporal analysis of forest loss related to cocaine trafficking in Central America

    Sesnie, Steven E.; Tellman, Beth; Wrathall, David; McSweeney, Kendra; Nielsen, Erik; Benessaiah, Karina; Wang, Ophelia; Rey, Luis

    2017-05-01

    A growing body of evidence suggests that criminal activities associated with drug trafficking networks are a progressively important driver of forest loss in Central America. However, the scale at which drug trafficking represents a driver of forest loss is not presently known. We estimated the degree to which narcotics trafficking may contribute to forest loss using an unsupervised spatial clustering of 15 spatial and temporal forest loss patch metrics developed from global forest change data. We distinguished anomalous forest loss from background loss patches for each country exhibiting potential ‘narco-capitalized’ signatures which showed a statistically significant dissimilarity from other patches in terms of size, timing, and rate of forest loss. We also compared annual anomalous forest loss with the number of cocaine shipments and volume of cocaine seized, lost, or delivered at country- and department-level. For Honduras, results from linear mixed effects models showed a highly significant relationship between anomalous forest loss and the timing of increased drug trafficking (F = 9.90, p = 0.009) that also differed significantly from temporal patterns of background forest loss (t-ratio = 2.98, p = 0.004). Other locations of high forest loss in Central America showed mixed results. The timing of increased trafficking was not significantly related to anomalous forest loss in Guatemala and Nicaragua, but significantly differed in patch size compared to background losses. We estimated that cocaine trafficking could account for between 15% and 30% of annual national forest loss in these three countries over the past decade, and 30% to 60% of loss occurred within nationally and internationally designated protected areas. Cocaine trafficking is likely to have severe and lasting consequences in terms of maintaining moist tropical forest cover in Central America. Addressing forest loss in these and other tropical locations will require a stronger

  2. Covariability of Central America/Mexico winter precipitation and tropical sea surface temperatures

    Pan, Yutong; Zeng, Ning; Mariotti, Annarita; Wang, Hui; Kumar, Arun; Sánchez, René Lobato; Jha, Bhaskar

    2018-06-01

    In this study, the relationships between Central America/Mexico (CAM) winter precipitation and tropical Pacific/Atlantic sea surface temperatures (SSTs) are examined based on 68-year (1948-2015) observations and 59-year (1957-2015) atmospheric model simulations forced by observed SSTs. The covariability of the winter precipitation and SSTs is quantified using the singular value decomposition (SVD) method with observational data. The first SVD mode relates out-of-phase precipitation anomalies in northern Mexico and Central America to the tropical Pacific El Niño/La Niña SST variation. The second mode links a decreasing trend in the precipitation over Central America to the warming of SSTs in the tropical Atlantic, as well as in the tropical western Pacific and the tropical Indian Ocean. The first mode represents 67% of the covariance between the two fields, indicating a strong association between CAM winter precipitation and El Niño/La Niña, whereas the second mode represents 20% of the covariance. The two modes account for 32% of CAM winter precipitation variance, of which, 17% is related to the El Niño/La Niña SST and 15% is related to the SST warming trend. The atmospheric circulation patterns, including 500-hPa height and low-level winds obtained by linear regressions against the SVD SST time series, are dynamically consistent with the precipitation anomaly patterns. The model simulations driven by the observed SSTs suggest that these precipitation anomalies are likely a response to tropical SST forcing. It is also shown that there is significant potential predictability of CAM winter precipitation given tropical SST information.

  3. A revision of the spider genus Selenops Latreille, 1819 (Arachnida, Araneae, Selenopidae) in North America, Central America and the Caribbean.

    Crews, Sarah C

    2011-01-01

    The spider genus Selenops Latreille, 1819 occurs in both the Old World and New World tropics and subtropics and contains nearly half of the species in the family Selenopidae Simon, 1897. In this paper the members of the genus Selenops found in North America, Central America, and on islands of the Caribbean are revised, excluding Cuban endemics. No taxonomic changes are currently made to the species from the southwestern United States. In total, 21 new species are described, including Selenops arikoksp. n., Selenops chamelasp. n., Selenops amonasp. n., Selenops bawekasp. n., Selenops bocacanadensissp. n., Selenops enriquillosp. n, Selenops ixchelsp. n., Selenops huetocatlsp. n., Selenops kalinagosp. n., Selenops oviedosp. n., Selenops morrosp. n., Selenops deniasp. n., Selenops duansp. n., Selenops malinalxochitlsp. n., Selenops oricuajosp. n., Selenops petenajtoysp. n., Selenops guerrerosp. n., Selenops makimakisp. n., Selenops souligasp. n., Selenops wilmotorumsp. n., and Selenops wilsonisp. n. Six species names were synonymized: Selenops lunatus Muma, 1953 syn. n. =Selenops candidus Muma, 1953; Selenops tehuacanus Muma 1953 syn. n., Selenops galapagoensis Banks, 1902 syn. n. and Selenops vagabundus Kraus, 1955 syn. n. = Selenops mexicanus Keyserling, 1880; Selenops santibanezi Valdez-Mondragón, 2010 syn. n. = Selenops nigromaculatus Keyserling, 1880; and Selenops salvadoranus Chamberlin, 1925 syn. n. = Selenops bifurcatus Banks, 1909. Lectotypes are designated for the following three species: Selenops marginalis F. O. Pickard-Cambridge, 1900 (♂), Selenops morosus Banks, 1898 (♂), and Selenops mexicanus Keyserling, 1880 (♀). The female neotype is designated for Selenops aissus Walckenaer, 1837. The males of Selenops bani Alayón-García, 1992 and Selenops marcanoi Alayón-García, 1992 are described for the first time, and the females of Selenops phaselus Muma, 1953 and Selenops geraldinae Corronca, 1996 are described for the first time. Almost all species

  4. The social perspective of desertification: Analysis of the public administration perception in Central America

    Garay Romero, Ingrid Carolina; Cabero Dieguez, Valentin

    2013-01-01

    Desertification is a complex problem and not only represents terrestrial ecosystems degradation. Today, it is well known that this process is linked to environmental deterioration as well as to economic and social factors, producing relevant impact in food security, poverty, migration and imbalance in many countries. Desertification perception analysis is essential in the design of the policies to fight this problem. Perception analysis in Central America is a very controversial issue and should be part of administration instruments and application strategies such as international agreements that will be included in public policies of the different States.

  5. Molecular typing of canine distemper virus strains reveals the presence of a new genetic variant in South America.

    Sarute, Nicolás; Pérez, Ruben; Aldaz, Jaime; Alfieri, Amauri A; Alfieri, Alice F; Name, Daniela; Llanes, Jessika; Hernández, Martín; Francia, Lourdes; Panzera, Yanina

    2014-06-01

    Canine distemper virus (CDV, Paramyxoviridae, Morbillivirus) is the causative agent of a severe infectious disease affecting terrestrial and marine carnivores worldwide. Phylogenetic relationships and the genetic variability of the hemagglutinin (H) protein and the fusion protein signal-peptide (Fsp) allow for the classification of field strains into genetic lineages. Currently, there are nine CDV lineages worldwide, two of them co-circulating in South America. Using the Fsp-coding region, we analyzed the genetic variability of strains from Uruguay, Brazil, and Ecuador, and compared them with those described previously in South America and other geographical areas. The results revealed that the Brazilian and Uruguayan strains belong to the already described South America lineage (EU1/SA1), whereas the Ecuadorian strains cluster in a new clade, here named South America 3, which may represent the third CDV lineage described in South America.

  6. A GPS Modeling Study of Earthquakes and Deformation in Northern Central America and along the Middle America Trench: 1999 to 2017

    Ellis, Andria P.

    Northern Central America is a tectonically complicated region prone to hazardous earthquakes due to the confluence of the Motagua-Polochic fault zone with the Middle America trench and strike-slip faults in the Central America volcanic arc. These three major fault zones converge at the western end of the Caribbean plate where the Cocos plate subducts under the North America and Caribbean plates. Literature from the 1970s and 1980s focused on whether a discrete North America-Caribbean-Cocos plate triple junction existed, and how the relative motions of the upper North America and Caribbean plates were accommodated. The discovery of a fourth major crustal block, the Central America forearc sliver, from seismic and geodetic observations made a three-plate triple junction geometrically impossible and introduced a new set of questions related to how deformation of the upper plate accommodates relative movements between the Caribbean plate, North America plate, and Central America forearc sliver where they intersect in the upper plate. My dissertation uses GPS and numerical modeling to measure and quantify earthquake transients and crustal deformation related to fault interactions in northern Central America and consists of three related chapters. The first chapter of my dissertation is a geodetic study of a M w = 7.4 subduction zone earthquake that occurred in 2012 offshore from our Guatemala GPS (Global Positioning System) network. For this study, I inverted coseismic site offsets and postseismic amplitudes to determine best-fitting coseismic and afterslip rupture distributions on the Middle America trench. I also determined the maximum likely viscoelastic deformation for the earthquake to test whether the transient postseismic deformation was dominated by fault afterslip or viscoelastic flow. This work was published in Geophysical Journal International in January 2015. The second chapter of my dissertation derives a new 200+ site GPS velocity field for northern

  7. Radical, reformist and aborted liberalism: origins of national regimes in Central America

    James MAHONEY

    2011-06-01

    Full Text Available During the twentieth century, the countries of Central America were characterized by remarkably different political regimes: military-authoritarianism in Guatemala and El Salvador, progressive democracy in Costa Rica and traditional-authoritarianism in Honduras and Nicaragua. This article explains these contrasting regime outcomes by exploring the agrarian and state-building reforms pursued by political leaders during the nineteenth– and early twentieth century liberal reform period. Based on differences in the transformation of state and class structures, three types of liberalism are identified: radical liberalism in Guatemala and El Salvador, reformist liberalism in Costa Rica and aborted liberalism in Honduras and Nicaragua. It is argued that these types of liberalism set the Central American countries on contrasting paths of political development, culminating in diverse regime outcomes.

  8. SALTRA: a regional program for workers' health and sustainable development in Central America.

    Wesseling, Catharina; Aragón, Aurora; Elgstrand, Kaj; Flores, Reinaldo; Hogstedt, Christer; Partanen, Timo

    2011-01-01

    In 2003, the university-based Program on Work and Health in Central America, SALTRA, was launched to build national and regional capacities in occupational safety and health with the goal of preventing and reducing poverty in Central America. SALTRA has implemented 20 projects including action projects in priority sectors (e.g., construction, sugarcane, hospitals, migrant coffee workers); strengthening of surveillance (occupational health profiles, carcinogenic exposures, fatal injuries and pesticides); a participatory model for training and risk monitoring by workers; building occupational health capacity for professionals, employers, and workers, with collaborating networks between the countries; strengthening of universities in work, environment, and health; studies of serious occupational and environmental situations; communication channels; and continued efforts to raise political awareness. SALTRA has placed issues of workers' health on political, business, and academic agendas throughout the region and has laid the foundations for achieving substantial future improvements in health conditions of all workers in the region. External evaluators envisioned SALTRA as an innovative development model.

  9. Ground motion prediction models for Central America using data from 1972 to 2010

    Schmidt-Diaz, Victor

    2014-01-01

    The most important seismological aspects of Central America were reviewed. The predominant soil types and their origin were also studied. A description of the data used in aspects such as information sources, ranges of magnitude, hypocentral and epicentral distance, and earthquake classification according to their origin is presented. A procedure of soil classification for all sites is considered, based on the average spectral ratios obtained at each station, as well as in the geological maps and lithological descriptions. Attenuation equations are obtained for crustal earthquakes using data from Central America and for subduction earthquakes using records from Costa Rica. The linear functional form was used, taking the geometric mean of peak acceleration (GM PGA) or the geometric mean of the pseudo-spectral acceleration (GM PSA) obtained from the response spectra for 5% of damping, as the dependent variable. The moment magnitude, hypocentral distance, and soil type were used as independent variables. In the case of GM PSA, a total of 22 frequencies were considered. The results are compared with models proposed by other authors. In general, it is observed that values obtained in this paper are lower. The response spectra were also compared with those proposed by the Codigo Sismico de Costa Rica. For all cases, the selected least-squares one-step method is showed the highest stability of the results. (author) [es

  10. Do pathogens become more virulent as they spread? Evidence from the amphibian declines in Central America.

    Phillips, Ben L; Puschendorf, Robert

    2013-09-07

    The virulence of a pathogen can vary strongly through time. While cyclical variation in virulence is regularly observed, directional shifts in virulence are less commonly observed and are typically associated with decreasing virulence of biological control agents through coevolution. It is increasingly appreciated, however, that spatial effects can lead to evolutionary trajectories that differ from standard expectations. One such possibility is that, as a pathogen spreads through a naive host population, its virulence increases on the invasion front. In Central America, there is compelling evidence for the recent spread of pathogenic Batrachochytrium dendrobatidis (Bd) and for its strong impact on amphibian populations. Here, we re-examine data on Bd prevalence and amphibian population decline across 13 sites from southern Mexico through Central America, and show that, in the initial phases of the Bd invasion, amphibian population decline lagged approximately 9 years behind the arrival of the pathogen, but that this lag diminished markedly over time. In total, our analysis suggests an increase in Bd virulence as it spread southwards, a pattern consistent with rapid evolution of increased virulence on Bd's invading front. The impact of Bd on amphibians might therefore be driven by rapid evolution in addition to more proximate environmental drivers.

  11. Multi-year GNSS monitoring of atmospheric IWV over Central and South America for climate studies

    Mendoza, Luciano; Bianchi, Clara; Fernández, Laura; Natali, María Paula; Meza, Amalia; Moirano, Juan

    2017-04-01

    Atmospheric water vapour has been acknowledged as an essential climate variable. Weather prediction and hazard assessment systems benefit from real-time observations, whereas long-term records contribute to climate studies. Nowadays, ground-based GNSS products have become widely employed, complementing satellite observations over the oceans. Although the past decade has seen a significant development of the GNSS infrastructure in Central and South America, its potential for atmospheric water vapour monitoring has not been fully exploited. With this in mind, we have performed a regional, seven-year long and homogeneous analysis, comprising 136 GNSS tracking stations, obtaining high-rate and continuous observations of column integrated water vapour and troposphere zenith total delay (Bianchi et al. 2016). As preliminary application for this data set, we have estimated local water vapour trends, their significance, and their relation with specific climate regimes. We have found evidence of drying at temperate regions in South America, at a rate of about 2% per decade, while a slow moistening of the troposphere over tropical regions is also weakly suggested by our results. Furthermore, we have assessed the regional performance of the empirical model GPT2w to blindly estimate troposphere delays. The model fairly reproduces the observed mean delays, including their annual and semi-annual variations. Nevertheless, a long-term evaluation has shown systematical biases, up to 20 mm, probably inherited form the underling atmospheric reanalysis. Additionally, the complete data set has been made openly available at a scientific repository (doi:10.1594/PANGAEA.858234). References: C. Bianchi, L. Mendoza, L. Fernandez, M. P. Natali, A. Meza, J. F. Moirano, Multi-year GNSS monitoring of atmospheric IWV over Central and South America for climate studies, Ann. Geophys., ISSN 0992-7689, eISSN 1432-0576, 34 (7), 623-639 (doi:10.5194/angeo-34-623-2016).

  12. What caused the cool summer over northern Central Asia, East Asia and central North America during 2009?

    Ha, Kyung-Ja; Chu, Jung-Eun; Lee, June-Yi; Wang, Bin; Hameed, Saji N; Watanabe, Masahiro

    2012-01-01

    Cool and wet weather conditions hit northern Central Asia, East Asia and central North America during the 2009 summer in concert with a strong jet stream and a prominent meandering upper-level circulation in the Northern Hemisphere mid-latitudes despite the fact that the year 2009 is the fifth warmest year globally in the modern record. It is found that the conspicuous atmospheric variability in the entire Northern Hemisphere mid-latitudes during the summer of 2009 was caused by a combination of teleconnections associated with significant tropical thermal forcings, strong polar forcing, and interaction between high-frequency weather events and climate anomalies. The strong negative circumglobal teleconnection pattern associated with the deficient Indian summer monsoon rainfall and developing El Niño condition was the major contributor to the cool and wet summer in June. On the other hand, the July weather conditions were attributable to the high-latitude impact of the unprecedented negative Arctic Oscillation, together with the Rossby wave response to the subtropical heating generated by convective activities over the Western North Pacific summer monsoon region. It is also noted that enhanced storm track activity and frequent cold surges from high-latitudes may have played a role in the cool and wet summer over the regions of interest. (letter)

  13. A review of bioinformatics training applied to research in molecular medicine, agriculture and biodiversity in Costa Rica and Central America.

    Orozco, Allan; Morera, Jessica; Jiménez, Sergio; Boza, Ricardo

    2013-09-01

    Today, Bioinformatics has become a scientific discipline with great relevance for the Molecular Biosciences and for the Omics sciences in general. Although developed countries have progressed with large strides in Bioinformatics education and research, in other regions, such as Central America, the advances have occurred in a gradual way and with little support from the Academia, either at the undergraduate or graduate level. To address this problem, the University of Costa Rica's Medical School, a regional leader in Bioinformatics in Central America, has been conducting a series of Bioinformatics workshops, seminars and courses, leading to the creation of the region's first Bioinformatics Master's Degree. The recent creation of the Central American Bioinformatics Network (BioCANET), associated to the deployment of a supporting computational infrastructure (HPC Cluster) devoted to provide computing support for Molecular Biology in the region, is providing a foundational stone for the development of Bioinformatics in the area. Central American bioinformaticians have participated in the creation of as well as co-founded the Iberoamerican Bioinformatics Society (SOIBIO). In this article, we review the most recent activities in education and research in Bioinformatics from several regional institutions. These activities have resulted in further advances for Molecular Medicine, Agriculture and Biodiversity research in Costa Rica and the rest of the Central American countries. Finally, we provide summary information on the first Central America Bioinformatics International Congress, as well as the creation of the first Bioinformatics company (Indromics Bioinformatics), spin-off the Academy in Central America and the Caribbean.

  14. Head and neck cancer burden and preventive measures in Central and South America.

    Perdomo, Sandra; Martin Roa, Guillermo; Brennan, Paul; Forman, David; Sierra, Mónica S

    2016-09-01

    Central and South America comprise one of the areas characterized by high incidence rates for head and neck cancer. We describe the geographical and temporal trends in incidence and mortality of head and neck cancers in the Central and South American region in order to identify opportunities for intervention on the major identified risk factors: tobacco control, alcohol use and viral infections. We obtained regional- and national-level incidence data from 48 population-based cancer registries in 13 countries and cancer deaths from the WHO mortality database for 18 countries. Age-standardized incidence (ASR) and mortality (ASMR) rates per 100,000 person-years were estimated. Brazil had the highest incidence rates for oral and pharyngeal cancer in the region for both sexes, followed by Cuba, Uruguay and Argentina. Cuba had the highest incidence and mortality rates of laryngeal cancer in the region for males and females. Overall, males had rates about four times higher than those in females. Most countries in the region have implemented WHO recommendations for both tobacco and alcohol public policy control. Head and neck squamous-cell cancer (HNSCC) incidence and mortality rates in the Central and South America region vary considerably across countries, with Brazil, Cuba, French Guyana, Uruguay and Argentina experiencing the highest rates in the region. Males carry most of the HNSCC burden. Improvement and implementation of comprehensive tobacco and alcohol control policies as well as the monitoring of these factors are fundamental to prevention of head and neck cancers in the region. Copyright © 2015 International Agency for Research on Cancer. Published by Elsevier Ltd.. All rights reserved.

  15. Genetic structure of Quechua-speakers of the Central Andes and geographic patterns of gene frequencies in South Amerindian populations.

    Luiselli, D; Simoni, L; Tarazona-Santos, E; Pastor, S; Pettener, D

    2000-09-01

    A sample of 141 Quechua-speaking individuals of the population of Tayacaja, in the Peruvian Central Andes, was typed for the following 16 genetic systems: ABO, Rh, MNSs, P, Duffy, AcP1, EsD, GLOI, PGM1, AK, 6-PGD, Hp, Gc, Pi, C3, and Bf. The genetic structure of the population was analyzed in relation to the allele frequencies available for other South Amerindian populations, using a combination of multivariate and multivariable techniques. Spatial autocorrelation analysis was performed independently for 13 alleles to identify patterns of gene flow in South America as a whole and in more specific geographic regions. We found a longitudinal cline for the AcP1*a and EsD*1 alleles which we interpreted as the result of an ancient longitudinal expansion of a putative ancestral population of modern Amerindians. Monmonnier's algorithm, used to identify areas of sharp genetic discontinuity, suggested a clear east-west differentiation of native South American populations, which was confirmed by analysis of the distribution of genetic distances. We suggest that this pattern of genetic structures is the consequence of the independent peopling of western and eastern South America or to low levels of gene flow between these regions, related to different environmental and demographic histories. Copyright 2000 Wiley-Liss, Inc.

  16. Drought assessment for cropland of Central America using course-resolution remote sensing data

    Chen, C. F.; Nguyen, S. T.; Chen, C. R.; Chiang, S. H.; Chang, L. Y.; Khin, L. V.

    2015-12-01

    Drought is one of the most frequent and costliest natural disasters, which imposes enormous effects to human societies and ecosystems. Agricultural drought is referred to an interval of time, such as weeks or months, when the soil moisture supply of a region consistently falls below the appropriate moisture supply leading to negative impacts on agricultural production. Millions of households in Central America were dependent upon major food crops, including maize, beans, and sorghum, for their daily subsistence. In recent years, impacts of climate change through global warming in forms of higher temperature and widespread rainfall deficits have however triggered severe drought during the primera cropping season (April-August) in the study region, causing profound impacts on agriculture, crop production losses, increased market food prices, as well as food security issues. This study focuses on investigating agricultural droughts for cropland of Central America using the Moderate Resolution Imaging Spectroradiometer (MODIS) data. We processed the data for a normal year 2013 and an abnormal year 2014 using a simple vegetation health index (VHI) that is developed based on the temperature condition index (TCI) and vegetation condition index (VCI). The VHI results were validated using the Advanced Microwave Scanning Radiometer 2 (AMSR2) precipitation data and temperature vegetation dryness index (TVDI) that is developed based on the empirical analysis of TCI and VCI data. The correlation coefficients (r) obtained by comparisons between the VHI data and the AMSR2 precipitation and TVDI data were higher than 0.62 and -0.61, respectively. The severe drought was intensive during the dry season (January-April) and likely backed to normal conditions in May with the onset of rainy season. The larger area of serve drought was observed for the 2014 primera season, especially during April-July. When investigating the cultivated areas affected by severe drought in the primera

  17. [Population mobility and HIV/AIDS in Central America and Mexico].

    Leyva-Flores, René; Aracena-Genao, Belkis; Serván-Mori, Edson

    2014-09-01

    Estimate the magnitude of the association between population mobility, measured by net migration rate (NMR), and HIV prevalence in Central America and Mexico. Using time series models, based on public information from UNAIDS, UNDP, ECLAC, and the World Bank for the period 1990-2009, this association was studied in individuals aged 15-49 years, and adjusted for socioeconomic factors (education, unemployment, life expectancy, and income). NMR was negative in all countries except Costa Rica and Panama. Unadjusted results of the model show a positive association and that NMR can explain 6% of recorded HIV prevalence. When socioeconomic cofactors are included by country (education, health, and income), the magnitude increases to 9% (PCentral America and Mexico, although large gaps persist among countries. The modest association observed between population mobility and HIV prevalence is conditioned by the socioeconomic status of the countries studied. Information availability limited the study's ability to establish the existence of this association with greater certainty. Accordingly, based on available information, it is not possible to affirm that migration plays a key role in the spread of HIV.

  18. Love in the Time of War. Affections and Disaffections in the Testimonial Literature of Central America

    José Domingo Carrillo Padilla

    2013-07-01

    Full Text Available The article aims to know the relationships established between the militants of the armed movements. Also want to be aware of the relationship model that prevailed. To achieve the proposed objectives, leave aside the narratives that glorify the armed movements, prevents build heroes to taste, rather, is a narrative of the adventures and the loving sinventuras who sought by weapons, to relieve the power ruler in Central America in the second half of the 20th century. The relationships established between the militants of the armed movements, regulated by traditional institutions such as marriage and free joints. In this article, because the nature of the sources this was said, emphasis in heterosexual affective relationships. There is know in the same way, homosexual relations between the guerrillas. Taboo because it means to infringe against the virility of men in arms and the model of femininity established by society. Son amores that even they dare not speak its name.

  19. The Spanish decentralised international cooperation in Central America in the area of municipalism and decentralisation

    Mariana Haedo

    2005-05-01

    Full Text Available In an attempt to link the international dimension with the local one, this article lays out an approach to the situation of Spanish decentralised international cooperation in the area of municipalism and decentralisation in the countries of Central America. In the firstplace, it offers a characterisation of the current state of Spanish decentralised cooperation in order to thus frame the cooperation actions carried out by the Barcelona Provincial Council; the UIM (Unión Iberoamericana de Municipios together with CEMCI (Centro de Estudios Municipales y de Cooperación Internacional; and the Confederación de Fondos de Cooperación y Solidaridad. Finally, it describes bankruptcies and it recovers some of the achievements ofthis kind of cooperation specifically in reference to the field of municipalism.

  20. Suitability of soil bioengineering techniques in Central America: a case study in Nicaragua

    Petrone, A.; Preti, F.

    2008-10-01

    In the last few years "D. I. A. F." (Department of Agriculture and Forestry Engineering of Florence University), has been testing the effectiveness of soil bioengineering techniques in Central America. The focus of the present study was to find out which native plants were most suited for soil bioengineering purposes, particularly in the realization of riverbank protection in Nicaragua. Furthermore, we have also been aiming at economic efficiency. These techniques are appropriate for sustainable watershed management especially in underdeveloped countries. Concerning the plants to be used we experimented four native species. Gliricidia Sepium, Cordia dentata and Jatropha curcas are suitable for soil bioengineering more than Bursera Simaruba. Economically speaking, the sustainability of such interventions in underdeveloped countries, has been shown by the evaluation of the cost of riverbank protection using vegetated crib-walls in Nicaragua compared to the cost in different contexts.

  1. First record of the invasive Asian fish tapeworm Bothriocephalus acheilognathi in Honduras, Central America.

    Salgado-Maldonado, Guillermo; Matamoros, Wilfredo A; Kreiser, Brian R; Caspeta-Mandujano, Juan Manuel; Mendoza-Franco, Edgar F

    2015-01-01

    This paper provides the first report of the invasive Asian fish tapeworm, Bothriocephalus acheilognathi Yamaguti, 1934, in Honduras. The cestode was found in Profundulus portillorum (Cyprinodontiformes: Profundulidae), which represents a new host record, and which is a member of a genus faced with a variety of conservation challenges, now potentially complicated by the presence of this pathogenic cestode. Nearly complete sequence data from the ITS-1 5.8S and ITS-2 regions corroborate the determination based on morphological characteristics. Several species of carp were introduced to Honduras for aquaculture purposes in the early 1980s and the presence of the Asian fish tapeworm in Honduras may be related to these introductions. In addition, this report documents the currently known geographical distribution of this parasite in Central America, first recorded from Panamá and now from Honduras. © G. Salgado-Maldonado et al., published by EDP Sciences, 2015.

  2. Satellite-based detection of volcanic sulphur dioxide from recent eruptions in Central and South America

    D. Loyola

    2008-01-01

    Full Text Available Volcanic eruptions can emit large amounts of rock fragments and fine particles (ash into the atmosphere, as well as several gases, including sulphur dioxide (SO2. These ejecta and emissions are a major natural hazard, not only to the local population, but also to the infrastructure in the vicinity of volcanoes and to aviation. Here, we describe a methodology to retrieve quantitative information about volcanic SO2 plumes from satellite-borne measurements in the UV/Visible spectral range. The combination of a satellite-based SO2 detection scheme and a state-of-the-art 3D trajectory model enables us to confirm the volcanic origin of trace gas signals and to estimate the plume height and the effective emission height. This is demonstrated by case-studies for four selected volcanic eruptions in South and Central America, using the GOME, SCIAMACHY and GOME-2 instruments.

  3. Mercury in Forage Fish from Mexico and Central America: Implications for Fish-Eating Birds.

    Elliott, John E; Kirk, David A; Elliott, Kyle H; Dorzinsky, Jessica; Lee, Sandi; Inzunza, Ernesto Ruelas; Cheng, Kimberly M T; Scheuhammer, Tony; Shaw, Patrick

    2015-11-01

    Mercury (Hg) is a global contaminant of aquatic food chains. Aquatic birds, such as the osprey (Pandion haliaetus), with migratory populations breeding in Canada and the northern United States and wintering in the Central and South America, can be exposed to mercury on both the breeding and wintering ranges. We examined Hg levels in 14 fish taxa from 24 osprey wintering sites identified from satellite telemetry. Our main goal was to determine whether fish species that feature in the diet of overwintering and resident fish-eating birds reached toxicity thresholds for Hg. Mean Hg levels in fish whole carcasses ranged from a high of 0.18 µg g(-1) (wet weight) in Scomberomorus sierra to a low of 0.009 µg g(-1) in Catostomidae. Average Hg levels were within published toxicity threshold values in forage fish for only two sites in Mexico (Puerto Vallarta and San Blas Estuary), and all were marine species, such as mackerel (Scomberomorus sierra), sea catfish (Ariopus spp.), and sardinas species (Centropomus spp.). Except for one sample from Nicaragua, sea catfish from Puerto Morazan, none of the fish from sites in Central America had Hg levels which exceeded the thresholds. Nonmetric multidimensional scaling revealed geographical differences in Hg levels with significant pairwise differences between sites along the Pacific Ocean (Mexico) versus the Bay of Campeche, partly due to differences in species composition of sampled fish (and species distributions). Hg increased with trophic level, as assessed by nitrogen stable isotope ratios (δ(15)N but not δ(13)C), in freshwater and marine, but not estuarine, environments. Hg concentrations in forage fish do not account for the elevated Hg reported for many osprey populations on the breeding grounds, thus primary sources of contamination appear to be in the north.

  4. Imaging paleoslabs in the D″ layer beneath Central America and the Caribbean using seismic waveform inversion.

    Borgeaud, Anselme F E; Kawai, Kenji; Konishi, Kensuke; Geller, Robert J

    2017-11-01

    D″ (Dee double prime), the lowermost layer of the Earth's mantle, is the thermal boundary layer (TBL) of mantle convection immediately above the Earth's liquid outer core. As the origin of upwelling of hot material and the destination of paleoslabs (downwelling cold slab remnants), D″ plays a major role in the Earth's evolution. D″ beneath Central America and the Caribbean is of particular geodynamical interest, because the paleo- and present Pacific plates have been subducting beneath the western margin of Pangaea since ~250 million years ago, which implies that paleoslabs could have reached the lowermost mantle. We conduct waveform inversion using a data set of ~7700 transverse component records to infer the detailed three-dimensional S-velocity structure in the lowermost 400 km of the mantle in the study region so that we can investigate how cold paleoslabs interact with the hot TBL above the core-mantle boundary (CMB). We can obtain high-resolution images because the lowermost mantle here is densely sampled by seismic waves due to the full deployment of the USArray broadband seismic stations during 2004-2015. We find two distinct strong high-velocity anomalies, which we interpret as paleoslabs, just above the CMB beneath Central America and Venezuela, respectively, surrounded by low-velocity regions. Strong low-velocity anomalies concentrated in the lowermost 100 km of the mantle suggest the existence of chemically distinct denser material connected to low-velocity anomalies in the lower mantle inferred by previous studies, suggesting that plate tectonics on the Earth's surface might control the modality of convection in the lower mantle.

  5. Conservation biogeography of red oaks (Quercus, section Lobatae) in Mexico and Central America.

    Torres-Miranda, Andrés; Luna-Vega, Isolda; Oyama, Ken

    2011-02-01

    Oaks are dominant trees and key species in many temperate and subtropical forests in the world. In this study, we analyzed patterns of distribution of red oaks (Quercus, section Lobatae) occurring in Mexico and Central America to determine areas of species richness and endemism to propose areas of conservation. Patterns of richness and endemism of 75 red oak species were analyzed using three different units. Two complementarity algorithms based on species richness and three algorithms based on species rarity were used to identify important areas for conservation. A simulated annealing analysis was performed to evaluate and formulate effective new reserves for red oaks that are useful for conserving the ecosystems associated with them after the systematic conservation planning approach. Two main centers of species richness were detected. The northern Sierra Madre Oriental and Serranías Meridionales of Jalisco had the highest values of endemism. Fourteen areas were considered as priorities for conservation of red oak species based on the 26 priority political entities, 11 floristic units and the priority grid-cells obtained in the complementarity analysis. In the present network of Natural Protected Areas in Mexico and Central America, only 41.3% (31 species) of the red oak species are protected. The simulated annealing analysis indicated that to protect all 75 species of red oaks, 12 current natural protected areas need to be expanded by 120000 ha of additional land, and 26 new natural protected areas with 512500 ha need to be created. Red oaks are a useful model to identify areas for conservation based on species richness and endemism as a result of their wide geographic distribution and a high number of species. We evaluated and reformulated new reserves for red oaks that are also useful for the conservation of ecosystems associated with them.

  6. Seismic hazard map of North and Central America and the Caribbean

    K. M. Shedlock

    1999-06-01

    Full Text Available Minimization of the loss of life, property damage, and social and economic disruption due to earthquakes depends on reliable estimates of seismic hazard. National, state, and local governments, decision makers, engineers, planners, emergency response organizations, builders, universities, and the general public require seismic hazard estimates for land use planning, improved building design and construction (including adoption of building construction codes, emergency response preparedness plans, economic forecasts, housing and employment decisions, and many more types of risk mitigation. The seismic hazard map of North and Central America and the Caribbean is the concatenation of various national and regional maps, involving a suite of approaches. The combined maps and documentation provide a useful regional seismic hazard framework and serve as a resource for any national or regional agency for further detailed studies applicable to their needs. This seismic hazard map depicts Peak Ground Acceleration (PGA with a 10% chance of exceedance in 50 years. PGA, a short-period ground motion parameter that is proportional to force, is the most commonly mapped ground motion parameter because current building codes that include seismic provisions specify the horizontal force a building should be able to withstand during an earthquake. This seismic hazard map of North and Central America and the Caribbean depicts the likely level of short-period ground motion from earthquakes in a fifty-year window. Short-period ground motions effect short-period structures (e.g., one-to-two story buildings. The highest seismic hazard values in the region generally occur in areas that have been, or are likely to be, the sites of the largest plate boundary earthquakes.

  7. Plate rotations, fault slip rates, fault locking, and distributed deformation in northern Central America from 1999-2017 GPS observations

    Ellis, A. P.; DeMets, C.; Briole, P.; Cosenza, B.; Flores, O.; Guzman-Speziale, M.; Hernandez, D.; Kostoglodov, V.; La Femina, P. C.; Lord, N. E.; Lasserre, C.; Lyon-Caen, H.; McCaffrey, R.; Molina, E.; Rodriguez, M.; Staller, A.; Rogers, R.

    2017-12-01

    We describe plate rotations, fault slip rates, and fault locking estimated from a new 100-station GPS velocity field at the western end of the Caribbean plate, where the Motagua-Polochic fault zone, Middle America trench, and Central America volcanic arc faults converge. In northern Central America, fifty-one upper-plate earthquakes caused approximately 40,000 fatalities since 1900. The proximity of main population centers to these destructive earthquakes and the resulting loss of human life provide strong motivation for studying the present-day tectonics of Central America. Plate rotations, fault slip rates, and deformation are quantified via a two-stage inversion of daily GPS position time series using TDEFNODE modeling software. In the first stage, transient deformation associated with three M>7 earthquakes in 2009 and 2012 is estimated and removed from the GPS position time series. In Stage 2, linear velocities determined from the corrected GPS time series are inverted to estimate deformation within the western Caribbean plate, slip rates along the Motagua-Polochic faults and faults in the Central America volcanic arc, and the gradient of extension in the Honduras-Guatemala wedge. Major outcomes of the second inversion include the following: (1) Confirmation that slip rates on the Motagua fault decrease from 17-18 mm/yr at its eastern end to 0-5 mm/yr at its western end, in accord with previous results. (2) A transition from moderate subduction zone locking offshore from southern Mexico and parts of southern Guatemala to weak or zero coupling offshore from El Salvador and parts of Nicaragua along the Middle America trench. (3) Evidence for significant east-west extension in southern Guatemala between the Motagua fault and volcanic arc. Our study also shows evidence for creep on the eastern Motagua fault that diminishes westward along the North America-Caribbean plate boundary.

  8. Warm and Dry Spells (WDS in Austral Winter over Central South America

    P. Satyamurty

    2007-06-01

    Full Text Available The horizontal and vertical structure of unusually warm and dry spells (WDS over the central parts of South America during the winter and post-winter months (JJAS are studied. During WDS the mean temperature and humidity anomalies over central Brazil are about +4.1°C and −13.2%, respectively. The mean duration of WDS is 11 days and their mean frequency is less than one per year during the months of JJAS. Apparently, WDS have no preference for the phase of ENSO. Widespread and persistent subsidence in the middle troposphere is observed in tropical Brazil during WDS, which renders the lower tropospheric air warm and dry. The negative anomalies of the specific humidity are observed to be associated with the subsidence regions. A strong, slow moving ridge in the eastern South Pacific and a low-pressure center in northern Argentina are important surface characteristics during the WDS. A more detailed investigation of two specific WDS events, a strong event (August–September 1999 and a moderate one (June 2002, shows a blocking-like situation in the 500-hPa geopotential and surface pressure fields in the Pacific. The South Atlantic subtropical high somewhat approaches the continent. Strong northerlies over the central and eastern parts of Brazil are also observed in the lower troposphere. During WDS the regional circulation acquires summertime characteristics, except for the absence of precipitation, and the circulation in the meridional plane is in the opposite sense from the Hadley circulation. A frontal system, supported by a 500-hPa trough, advances into central Brazil, causing the dissipation of the anomalous situation.

  9. Catalogo General de Universidades, 1970-1971: Federacion de Universidades Privadas de America Central y Panama (General Catalog of Universities, 1970-1971: Federation of Private Universities of Central America and Panama).

    Federacion de Universidades Privadas de America Central y Panama, Guatemala City (Guatemala).

    This document contains the 1970-1971 catalogues of five universities belonging to the Federation of Private Universities of Central America and Panama (FUPAC). The catalogues provide information on university administrators and staff, historical background, admission requirements, degree programs, scholarships, and courses. The catalogues included…

  10. Geoid modeling in Mexico and the collaboration with Central America and the Caribbean.

    Avalos, D.; Gomez, R.

    2012-12-01

    The model of geoidal heights for Mexico, named GGM10, is presented as a geodetic tool to support vertical positioning in the context of regional height system unification. It is a purely gravimetric solution computed by the Stokes-Helmert technique in resolution of 2.5 arc minutes. This product from the Instituto Nacional de Estadistica y Geografia (INEGI) is released together with a series of 10 gravimetric models which add to the improvements in description of the gravity field. In the recent years, the INEGI joined the initiative of the U.S. National Geodetic Survey and the Canada's Geodetic Survey Division to promote the regional height system unification. In an effort to further improve the compatibility among national geoid models in the region, the INEGI has begun to champion a network of specialists that includes national representatives from Central America and the Caribbean. Through the opening of opportunities for training and more direct access to international agreements and discussions, the tropical region is gaining participation. Now a significantly increased number of countries is pushing for a future North and Central American geoid-based vertical datum as support of height system unification.eoidal height in Mexico, mapped from the model GGM10.

  11. International relations among Tom Thumbs: Taiwan as provider of aid Central America

    Francisco Javier Haro Navejas

    2007-06-01

    Full Text Available This paper analyzes the Official Development Aid (AOD that has as its source Taiwan and as its destination Central America. It has three basic aims: Firstly, there is a huge bibliographic vacuum on the topic of these pages. Beginning filling it is an academic need. Even some intellectuals feel that they should lean against either Beijing or Taipei, that if they write on Taiwan they should defend or attack one of the contending parties. Here it is seen that a study close to objectivity is possible. Secondly, most of the research in International Relations has been focused on topics related with power itself or with just elements related with hard power. AOD is both hard and soft power, therefore this paper shades light to the dark side partially viewing international relations from a theoretical perspective were interactions help to construct identities and cooperation is an essential variable of world politics. Finally, it will be seen below that the Taiwanese cooperativeeconomic actions are helpful to the progress of poor parts of the Central American region and are helpful to create domestic markets with strong links with the world market deepening the economic integration both regional and global. Aid from Taiwan and some other countries, mainly through the transmission of know how, could be of assistance in surmounting huge troubles. Aid is vital because some of Central American’s problems are being exported mainly to México and the United States under the form, just to give an example, of Mara Salvatrucha gangs source of violence and drug trafficking. It is not meaningless to stress that Taiwanese ODA is by far not enough and is very small in the international context.

  12. 77 FR 15397 - Dominican Republic-Central America-United States Free Trade Agreement; Notice of Determination...

    2012-03-15

    ... lack thereof denied workers their rights under the laws of the Dominican Republic relating to freedom of association, the right to organize, child labor, forced labor, the right to bargain collectively... (``submissions'') regarding labor law matters in Central America and the Dominican Republic. A Federal Register...

  13. Two new genera of metalmark butterflies of North and Central America (Lepidoptera, Riodinidae

    Marysol Trujano-Ortega

    2018-01-01

    Full Text Available Two new genera of Riodinidae (Insecta: Lepidoptera are described, Neoapodemia Trujano-Ortega, gen. n. (Neoapodemia nais (W. H. Edwards, 1876, comb. n., N. chisosensis Freeman, 1964, comb. n. and Plesioarida Trujano-Ortega & García-Vázquez, gen. n. (Plesioarida palmerii palmerii (W. H. Edwards, 1870, comb. n., P. palmerii arizona (Austin, [1989], comb. n., P. palmerii australis (Austin, [1989], comb. n., P. hepburni hepburni (Godman & Salvin, 1886, comb. n., P. hepburni remota (Austin, 1991, comb. n., P. murphyi (Austin, [1989], comb. n., P. hypoglauca hypoglauca (Godman & Salvin, 1878, comb. n., P. hypoglauca wellingi (Ferris, 1985, comb. n., P. walkeri (Godman & Salvin, 1886, comb. n., P. selvatica (De la Maza & De la Maza, 2017, comb. n.. Neoapodemia Trujano-Ortega, gen. n. is distributed in the southwestern USA and northeastern Mexico, while Plesioarida Trujano-Ortega & García-Vázquez, gen. n. is present from the southern USA to Central America. Species of these genera were previously classified as Apodemia C. Felder & R. Felder but molecular and morphological evidence separate them as new taxa. Morphological diagnoses and descriptions are provided for both new genera, including the main distinctive characters from labial palpi, prothoracic legs, wing venation and genitalia, as well as life history traits. A molecular phylogeny of one mitochondrial gene (COI and two nuclear genes (EF-1a and wg are also presented of most species of Apodemia, Neoapodemia Trujano-Ortega, gen. n., Plesioarida Trujano-Ortega & García-Vázquez, gen. n., and sequences of specimens from all tribes of Riodinidae. We compare the characters of Apodemia, Neoapodemia Trujano-Ortega, gen. n. and Plesioarida Trujano-Ortega & García-Vázquez, gen. n. and discuss the differences that support the description of these new taxa. This is a contribution to the taxonomy of the Riodinidae of North America of which the generic diversity is greater than previously recognized.

  14. Molecular Detection and Identification of Rickettsia Species in Ticks (Acari: Ixodidae) Collected From Belize, Central America.

    Polsomboon, Suppaluck; Hoel, David F; Murphy, Jittawadee R; Linton, Yvonne-Marie; Motoki, Maysa; Robbins, Richard G; Bautista, Kim; Bricen O, Ireneo; Achee, Nicole L; Grieco, John P; Ching, Wei-Mei; Chao, Chien-Chung

    2017-11-07

    Little is known about tick-borne rickettsial pathogens in Belize, Central America. We tested ixodid ticks for the presence of Rickettsia species in three of the six northern and western Belizean districts. Ticks were collected from domestic animals and tick drags over vegetation in 23 different villages in November 2014, February 2015, and May 2015. A total of 2,506 collected ticks were identified to the following species: Dermacentor nitens Neumann (46.69%), Rhipicephalus sanguineus (Latreille) (19.55%), Rhipicephalus microplus (Canestrini) (19.47%), Amblyomma cajennense complex (9.74%), Amblyomma maculatum Koch (3.47%), Amblyomma ovale Koch (0.68%), Ixodes nr affinis (0.16%), Amblyomma nr maculatum (0.12%), and Amblyomma nr oblongoguttatum (0.12%). Ticks were pooled according to species, life stage (larva, nymph, or adult), and location (n = 509) for DNA extraction and screened for genus Rickettsia by quantitative real-time polymerase chain reaction (qPCR). All 42 positive pools were found to be positive for spotted fever group (SFG) Rickettsia in pools of A. cajennense complex (n = 33), A. maculatum (n = 4), A. nr maculatum (n = 1), A. ovale (n = 1), R. sanguineus (n = 1), and I. nr affinis (n = 2). Rickettsia amblyommatis was identified from A. cajennense complex and A. nr maculatum. Rickettsia parkeri was found in A. maculatum, and Rickettsia sp. endosymbiont was detected in I. nr affinis. The presence of infected ticks suggests a risk of tick-borne rickettsioses to humans and animals in Belize. This knowledge can contribute to an effective tick management and disease control program benefiting residents and travelers. Published by Oxford University Press on behalf of Entomological Society of America 2017. This work is written by US Government employees and is in the public domain in the US.

  15. A biogeographical population genetics perspective of the colonization of cats in Latin America and temporal genetic changes in Brazilian cat populations

    Manuel Ruiz-García

    2008-01-01

    Full Text Available We used nine morphological genes to analyze cat populations from Mexico, the Dominican Republic, the Colombian, Brazilian and Peruvian Amazon, Bolivia and Brazil. Most populations were in Hardy-Weinberg equilibrium at the O locus. The highest allele frequencies so far detected at world level for alleles I (inhibitor and L (long hair were found at La Paz (Bolivia. The analyses revealed at least five cat gene pools in Latin America: These findings suggest that the current genetic distribution of cats in Latin America correlates with the colonization of the Americas during the XIV to XVIII centuries. Additionally, the cat populations of São Paulo, Rio de Janeiro and Manaus were sampled, to compare their 1996-2003 genetic profiles with those obtained in 1983. Generally, these genetic profiles seem temporally stable, which is important for comparing cat populations sampled in different years and decades.

  16. Sub-Saharan centralized biorepository for genetic and genomic research.

    Gasmelseed, Nagla; Elsir, Afrah Awad; Deblasio, Pasquale; Biunno, Ida

    2012-04-15

    Quality-assessed biomedical samples are essential for academia- and industry driven research on human diseases. The etiologies and the molecular genetic factors relevant in African diseases, including both infections and complex degenerative diseases as well as cancer, need to be studied using well annotated and well-preserved biosamples acquired from native African ethnic groups and compare the results with non-African populations and/or with Afro-Americans. However, a number of difficulties negatively impact on the possibility to obtain clinically annotated biological samples in most Sub-Saharan African countries. This is mainly due to major organizational problems, lack of clinical centres that can dedicate resources to research, as well as lack of facilities in which biomaterials can be properly processed and safely stored. Harmonization of biosample acquisition, storage phenotyping schemes and biocomputer infrastructures are the principal objectives of biological resource centers (BRCs). BRCs comprise biobanks of different formats (collection of blood, DNA, tissues, etc., annotated with medical, environmental, life-style and follow up data) a fundamental tool for molecular epidemiological studies aiming to increase excellence and efficacy of biomedical results, drug development and public health. BRCs provide large and highly controlled biomolecular resources necessary to meet the "omics" scientific platforms. Sudan may be a candidate nation to host such infrastructure, in view of its strategic geographical position and the already existing simple biobanking experiences connected with research groups in Central Sudan. Here, we describe the potential role of biobanks in African genetic studies aiming to dissect the eziopathogenesis of complex diseases in relation to environmental and life-style factors. Copyright © 2010 Elsevier B.V. All rights reserved.

  17. Genetic Diversity and Population Genetics of Mosquitoes (Diptera: Culicidae: Culex spp. from the Sonoran Desert of North America

    Edward Pfeiler

    2013-01-01

    Full Text Available The population genetics and phylogenetic relationships of Culex mosquitoes inhabiting the Sonoran Desert region of North America were studied using mitochondrial DNA and microsatellite molecular markers. Phylogenetic analyses of mitochondrial cytochrome c oxidase subunit I (COI from mosquitoes collected over a wide geographic area, including the Baja California peninsula, and mainland localities in southern Arizona, USA and Sonora, Mexico, showed several well-supported partitions corresponding to Cx. quinquefasciatus, Cx. tarsalis, and two unidentified species, Culex sp. 1 and sp. 2. Culex quinquefasciatus was found at all localities and was the most abundant species collected. Culex tarsalis was collected only at Tucson, Arizona and Guaymas, Sonora. The two unidentified species of Culex were most abundant at Navojoa in southern Sonora. Haplotype and nucleotide diversities in the COI gene segment were substantially lower in Cx. quinquefasciatus compared with the other three species. Analysis of molecular variance revealed little structure among seven populations of Cx. quinquefasciatus, whereas significant structure was found between the two populations of Cx. tarsalis. Evidence for an historical population expansion beginning in the Pleistocene was found for Cx. tarsalis. Possible explanations for the large differences in genetic diversity between Cx. quinquefasciatus and the other species of Culex are presented.

  18. Genetic Diversity and Population Genetics of Mosquitoes (Diptera: Culicidae: Culex spp.) from the Sonoran Desert of North America

    Pfeiler, Edward; Flores-López, Carlos A.; Mada-Vélez, Jesús Gerardo; Escalante-Verdugo, Juan; Markow, Therese A.

    2013-01-01

    The population genetics and phylogenetic relationships of Culex mosquitoes inhabiting the Sonoran Desert region of North America were studied using mitochondrial DNA and microsatellite molecular markers. Phylogenetic analyses of mitochondrial cytochrome c oxidase subunit I (COI) from mosquitoes collected over a wide geographic area, including the Baja California peninsula, and mainland localities in southern Arizona, USA and Sonora, Mexico, showed several well-supported partitions corresponding to Cx. quinquefasciatus, Cx. tarsalis, and two unidentified species, Culex sp. 1 and sp. 2. Culex quinquefasciatus was found at all localities and was the most abundant species collected. Culex tarsalis was collected only at Tucson, Arizona and Guaymas, Sonora. The two unidentified species of Culex were most abundant at Navojoa in southern Sonora. Haplotype and nucleotide diversities in the COI gene segment were substantially lower in Cx. quinquefasciatus compared with the other three species. Analysis of molecular variance revealed little structure among seven populations of Cx. quinquefasciatus, whereas significant structure was found between the two populations of Cx. tarsalis. Evidence for an historical population expansion beginning in the Pleistocene was found for Cx. tarsalis. Possible explanations for the large differences in genetic diversity between Cx. quinquefasciatus and the other species of Culex are presented. PMID:24302868

  19. Intra-Arc extension in Central America: Links between plate motions, tectonics, volcanism, and geochemistry

    Phipps Morgan, Jason; Ranero, Cesar; Vannucchi, Paola

    2010-05-01

    This study revisits the kinematics and tectonics of Central America subduction, synthesizing observations of marine bathymetry, high-resolution land topography, current plate motions, and the recent seismotectonic and magmatic history in this region. The inferred tectonic history implies that the Guatemala-El Salvador and Nicaraguan segments of this volcanic arc have been a region of significant arc tectonic extension; extension arising from the interplay between subduction roll-back of the Cocos Plate and the ~10-15 mm/yr slower westward drift of the Caribbean plate relative to the North American Plate. The ages of belts of magmatic rocks paralleling both sides of the current Nicaraguan arc are consistent with long-term arc-normal extension in Nicaragua at the rate of ~5-10 mm/yr, in agreement with rates predicted by plate kinematics. Significant arc-normal extension can ‘hide' a very large intrusive arc-magma flux; we suggest that Nicaragua is, in fact, the most magmatically robust section of the Central American arc, and that the volume of intrusive volcanism here has been previously greatly underestimated. Yet, this flux is hidden by the persistent extension and sediment infill of the rifting basin in which the current arc sits. Observed geochemical differences between the Nicaraguan arc and its neighbors which suggest that Nicaragua has a higher rate of arc-magmatism are consistent with this interpretation. Smaller-amplitude, but similar systematic geochemical correlations between arc-chemistry and arc-extension in Guatemala show the same pattern as the even larger variations between the Nicaragua arc and its neighbors. We are also exploring the potential implications of intra-arc extension for deformation processes along the subducting plate boundary and within the forearc ‘microplate'.

  20. The genetic legacy of multiple beaver reintroductions in Central Europe.

    Frosch, Christiane; Kraus, Robert H S; Angst, Christof; Allgöwer, Rainer; Michaux, Johan; Teubner, Jana; Nowak, Carsten

    2014-01-01

    The comeback of the Eurasian beaver (Castor fiber) throughout western and central Europe is considered a major conservation success. Traditionally, several subspecies are recognised by morphology and mitochondrial haplotype, each linked to a relict population. During various reintroduction programs in the 20th century, beavers from multiple source localities were released and now form viable populations. These programs differed in their reintroduction strategies, i.e., using pure subspecies vs. mixed source populations. This inhomogeneity in management actions generated ongoing debates regarding the origin of present beaver populations and appropriate management plans for the future. By sequencing of the mitochondrial control region and microsatellite genotyping of 235 beaver individuals from five selected regions in Germany, Switzerland, Luxembourg, and Belgium we show that beavers from at least four source origins currently form admixed, genetically diverse populations that spread across the study region. While regional occurrences of invasive North American beavers (n = 20) were found, all but one C. fiber bore the mitochondrial haplotype of the autochthonous western Evolutionary Significant Unit (ESU). Considering this, as well as the viability of admixed populations and the fact that the fusion of different lineages is already progressing in all studied regions, we argue that admixture between different beaver source populations should be generally accepted.

  1. Mobile populations and HIV/AIDS in Central America and Mexico: research for action.

    Bronfman, Mario N; Leyva, Rene; Negroni, Mirka J; Rueda, Celina M

    2002-12-01

    To present a multi-centre study that analyses the socioeconomic, cultural and political contexts that give rise to population mobility, and its relationship to vulnerability to sexually transmitted infections (STI)/HIV/AIDS, in order to provide information that can be used to design appropriate and focused interventions. In each of 11 transit stations (border towns, port cities, areas where mobile populations congregate) in Central America and Mexico, a household survey of the local population was conducted to analyse demographic, socioeconomic characteristics, and information known and opinions held about HIV/AIDS and mobile populations. In-depth interviews with key informants, community members and mobile populations were held to ascertain knowledge about prevention and transmission of STI/HIV/AIDS. Likewise, an ethnographic study was undertaken to identify interactions between local and mobile populations. The transit stations share low educational levels among the local population, few public services, repeated human rights violations, violence, poverty and corrupt authorities. Within this social context, transactional sex, sex for survival, rape and non-professional commercial sex happen in conditions that increase the risk of the transmission of STI/HIV, such as infrequent condom use. Migrant women and sex workers are particularly vulnerable in this context. A wide gap exists between information about STI/HIV transmission and reported prevention practices. Given the conditions that exist in these transit stations, interventions should be multisectoral, sustainable, and should defend the human rights of various groups, including women and people living with HIV/AIDS.

  2. [Optimization of registry of deaths from chronic kidney disease in agricultural communities in Central America].

    Escamilla-Cejudo, José Antonio; Báez, Jorge Lara; Peña, Rodolfo; Luna, Patricia Lorena Ruiz; Ordunez, Pedro

    2016-11-01

    Several Central American countries are seeing continued growth in the number of deaths from chronic kidney disease of nontraditional causes (CKDnT) among farm workers and there is underreporting. This report presents the results of a consensus process coordinated by the Pan American Health Organization/World Health Organization (PAHO/WHO), the United States Centers for Disease Control and Prevention (CDC), and the Latin American Society of Nephrology and Hypertension (SLANH). This consensus seeks to increase the probability of detecting and recording deaths from these causes. There has been recognition of the negative impact of the lack of a standardized instrument and the lack of training in the medical profession for adequate registration of the cause or causes of death. As a result of the consensus, the following has been proposed: temporarily use a code from the Codes for Special Purposes in the International Classification of Diseases (ICD-10); continue to promote use of the WHO international standardized instrument for recording causes and preceding events related to death; increase training of physicians responsible for filling out death certificates; take action to increase the coverage and quality of information on mortality; and create a decision tree to facilitate selection of CKDnT as a specific cause of death, while presenting the role that different regional and subregional mechanisms in the Region of the Americas should play in order to improve CKD and CKDnT mortality records.

  3. Medicinal Plants from Mexico, Central America, and the Caribbean Used as Immunostimulants

    Angel Josabad Alonso-Castro

    2016-01-01

    Full Text Available A literature review was undertaken by analyzing distinguished books, undergraduate and postgraduate theses, and peer-reviewed scientific articles and by consulting worldwide accepted scientific databases, such as SCOPUS, Web of Science, SCIELO, Medline, and Google Scholar. Medicinal plants used as immunostimulants were classified into two categories: (1 plants with pharmacological studies and (2 plants without pharmacological research. Medicinal plants with pharmacological studies of their immunostimulatory properties were subclassified into four groups as follows: (a plant extracts evaluated for in vitro effects, (b plant extracts with documented in vivo effects, (c active compounds tested on in vitro studies, and (d active compounds assayed in animal models. Pharmacological studies have been conducted on 29 of the plants, including extracts and compounds, whereas 75 plants lack pharmacological studies regarding their immunostimulatory activity. Medicinal plants were experimentally studied in vitro (19 plants and in vivo (8 plants. A total of 12 compounds isolated from medicinal plants used as immunostimulants have been tested using in vitro (11 compounds and in vivo (2 compounds assays. This review clearly indicates the need to perform scientific studies with medicinal flora from Mexico, Central America, and the Caribbean, to obtain new immunostimulatory agents.

  4. Medicinal Plants from Mexico, Central America, and the Caribbean Used as Immunostimulants

    Juárez-Vázquez, María del Carmen; Campos-Xolalpa, Nimsi

    2016-01-01

    A literature review was undertaken by analyzing distinguished books, undergraduate and postgraduate theses, and peer-reviewed scientific articles and by consulting worldwide accepted scientific databases, such as SCOPUS, Web of Science, SCIELO, Medline, and Google Scholar. Medicinal plants used as immunostimulants were classified into two categories: (1) plants with pharmacological studies and (2) plants without pharmacological research. Medicinal plants with pharmacological studies of their immunostimulatory properties were subclassified into four groups as follows: (a) plant extracts evaluated for in vitro effects, (b) plant extracts with documented in vivo effects, (c) active compounds tested on in vitro studies, and (d) active compounds assayed in animal models. Pharmacological studies have been conducted on 29 of the plants, including extracts and compounds, whereas 75 plants lack pharmacological studies regarding their immunostimulatory activity. Medicinal plants were experimentally studied in vitro (19 plants) and in vivo (8 plants). A total of 12 compounds isolated from medicinal plants used as immunostimulants have been tested using in vitro (11 compounds) and in vivo (2 compounds) assays. This review clearly indicates the need to perform scientific studies with medicinal flora from Mexico, Central America, and the Caribbean, to obtain new immunostimulatory agents. PMID:27042188

  5. High level of molecular and phenotypic biodiversity in Jatropha curcas from Central America compared to Africa, Asia and South America

    Montes Osorio, L.R.; Torres Salvador, A.F.; Jongschaap, R.E.E.; Azurdia, C.; Berduo, J.; Trindade, L.M.; Visser, R.G.F.; Loo, van E.N.

    2014-01-01

    Background The main bottleneck to elevate jatropha (Jatropha curcas L.) from a wild species to a profitable biodiesel crop is the low genetic and phenotypic variation found in different regions of the world, hampering efficient plant breeding for productivity traits. In this study, 182 accessions

  6. Geomorphological impact on agroforestry systems in the interior highlands of Nicaragua, Central America

    Mentler, Axel; Wriessnig, Karin; Ottner, Franz; Schomakers, Jasmin; Benavides González, Álvaro; Cisne Contreras, José Dolores; Querol Lipcovich, Daniel

    2013-04-01

    Cerro el Castillo is located in the NW of Nicaragua, Central America, close to the border of Honduras (Provincia Central de las Cordilleras) at 1000-1200m above sea level. In this region, small and medium-sized farms are agroforestry systems with mangos, avocados, coffee, papayas, bananas, strawberries, maize, pumpkins, beans and other vegetables. The production systems are strongly linked to facilities for raising small domestic animals and cows. Main regional agricultural production problems are steep slopes, soil erosion, varying precipitation and distribution, water management and the unstable family income. An investigation of topsoil properties with comparable management systems showed on small scales significant differences in key values of soil chemistry and mineralogy. The outline of the analytical parameters included determination of pH, electrical conductivity (EC), cation exchange capacity (CEC), organic carbon (TOC), dissolved organic carbon (DOC), total nitrogen (TN) and dissolved nitrogen (DN) in soil solution, and plant available nutrients (P and K). The soil's mineralogical composition was determined by X-ray diffraction analysis. The area is a highly weathered karst landscape within a tropical limestone region displaying different amounts of volcanic pyroclastic parent material. The dominant Nitisoils and Andosols show degraded argic and andic horizons along the upper half of the mountainside. The pH values in the topsoil are moderate from pH 5.0 to 5.6. The upland topsoil is decalcified and the amount of plant available phosphorous is very low with significant low Ca concentration at the sorption complex. The mineralogical composition points to the high weathering intensity of this area (high content of kaolinite and a lower concentration of potassium and plagioclase feldspars and andesite). Along the upper half of the mountain, the soil profiles show wider C:N ratios and lower amounts of organic matter. Topsoil at lower altitude and with a lower

  7. Why is Liberal Peace-building so Difficult? Some Lessons from Central America

    Sabine Kurtenbach

    2010-04-01

    Full Text Available According to the liberal peace-building paradigm the termination of war is a window of opportunity for fundamental change. Central America has been one of the first laboratories of international policies promoting the threefold transformation process of pacification, democratization and economic liberalization. Although none of the postwar countries (Nicaragua, El Salvador, Guatemala slipped back into war, serious deficits abound that can neither be explained as mere consequences of war nor as ‘normal’ developmental problems. The paper introduces an analytical framework locating these problems at the intersection between external influences, societal foundations, consequences of war and violence as well as peace-building. The comparative analysis of the three transformation processes – democratization, market economy and pacification – shows how path dependent patterns remain dominant while reform processes are fragile. This allows for an explanation of common features as well as differences inside the region. Resumen: ¿Por qué es tan difícil la construcción de una paz liberal? Algunas lecciones de América CentralDe acuerdo al paradigma liberal sobre la construcción de la paz, el fin de una guerra abre un abanico de oportunidades para introducir cambios fundamentales. América Central fue uno de los primeros laboratorios donde se aplicaron políticas internacionales que fomentaban el triple proceso de transformación compuesto por la pacificación, la democratización y la liberalización económica. Aunque ninguna de las sociedades de posguerra (Nicaragua, El Salvador, Guatemala volvió a recaer en ella, abundan graves deficiencias que no se pueden explicar ni como meras consecuencias del conflicto ni como problemas ‘normales’ de países en desarrollo. El artículo define un marco analítico que localiza estos problemas en la intersección de influencias externas, bases sociales, consecuencias de la guerra y violencia as

  8. Tsunami hazard assessment in El Salvador, Central America, from seismic sources through flooding numerical models.

    Álvarez-Gómez, J. A.; Aniel-Quiroga, Í.; Gutiérrez-Gutiérrez, O. Q.; Larreynaga, J.; González, M.; Castro, M.; Gavidia, F.; Aguirre-Ayerbe, I.; González-Riancho, P.; Carreño, E.

    2013-11-01

    El Salvador is the smallest and most densely populated country in Central America; its coast has an approximate length of 320 km, 29 municipalities and more than 700 000 inhabitants. In El Salvador there were 15 recorded tsunamis between 1859 and 2012, 3 of them causing damages and resulting in hundreds of victims. Hazard assessment is commonly based on propagation numerical models for earthquake-generated tsunamis and can be approached through both probabilistic and deterministic methods. A deterministic approximation has been applied in this study as it provides essential information for coastal planning and management. The objective of the research was twofold: on the one hand the characterization of the threat over the entire coast of El Salvador, and on the other the computation of flooding maps for the three main localities of the Salvadorian coast. For the latter we developed high-resolution flooding models. For the former, due to the extension of the coastal area, we computed maximum elevation maps, and from the elevation in the near shore we computed an estimation of the run-up and the flooded area using empirical relations. We have considered local sources located in the Middle America Trench, characterized seismotectonically, and distant sources in the rest of Pacific Basin, using historical and recent earthquakes and tsunamis. We used a hybrid finite differences-finite volumes numerical model in this work, based on the linear and non-linear shallow water equations, to simulate a total of 24 earthquake-generated tsunami scenarios. Our results show that at the western Salvadorian coast, run-up values higher than 5 m are common, while in the eastern area, approximately from La Libertad to the Gulf of Fonseca, the run-up values are lower. The more exposed areas to flooding are the lowlands in the Lempa River delta and the Barra de Santiago Western Plains. The results of the empirical approximation used for the whole country are similar to the results

  9. An investigation of thermal anomalies in the Central American volcanic chain and evaluation of the utility of thermal anomaly monitoring in the prediction of volcanic eruptions. [Central America

    Stoiber, R. E. (Principal Investigator); Rose, W. I., Jr.

    1975-01-01

    The author has identified the following significant results. Ground truth data collection proves that significant anomalies exist at 13 volcanoes within the test site of Central America. The dimensions and temperature contrast of these ten anomalies are large enough to be detected by the Skylab 192 instrument. The dimensions and intensity of thermal anomalies have changed at most of these volcanoes during the Skylab mission.

  10. Circulation of different lineages of dengue virus type 2 in Central America, their evolutionary time-scale and selection pressure analysis.

    Germán Añez

    Full Text Available Dengue is caused by any of the four serotypes of dengue virus (DENV-1 to 4. Each serotype is genetically distant from the others, and each has been subdivided into different genotypes based on phylogenetic analysis. The study of dengue evolution in endemic regions is important since the diagnosis is often made by nucleic acid amplification tests, which depends upon recognition of the viral genome target, and natural occurring mutations can affect the performance of these assays. Here we report for the first time a detailed study of the phylogenetic relationships of DENV-2 from Central America, and report the first fully sequenced DENV-2 strain from Guatemala. Our analysis of the envelope (E protein and of the open reading frame of strains from Central American countries, between 1999 and 2009, revealed that at least two lineages of the American/Asian genotype of DENV-2 have recently circulated in that region. In occasions the co-circulation of these lineages may have occurred and that has been suggested to play a role in the observed increased severity of clinical cases. Our time-scale analysis indicated that the most recent common ancestor for Central American DENV-2 of the American/Asian genotype existed about 19 years ago. Finally, we report positive selection in DENV-2 from Central America in codons of the genes encoding for C, E, NS2A, NS3, and NS5 proteins. Some of these identified codons are novel findings, described for the first time for any of the DENV-2 genotypes.

  11. Spread of butternut canker in North America, host range, evidence of resistance within butternut populations and conservation genetics

    M. E. Ostry; K. Woeste

    2004-01-01

    Butternut canker is killing trees throughout the range of butternut in North America and is threatening the viability of many populations in several areas. Although butternut is the primary host, other Juglans species and some hardwood species also are potential hosts. Evidence is building that genetic resistance within butternut populations may be...

  12. Correlation of proterozoic sediments of Western and Central Africa and South America based upon radiochronological and paleontological data

    Bonhomme, M.G.

    1982-01-01

    Nearly 70 new Rb-Sr isochron ages and many K-Ar conventional ages have been determined between 1975 and 1980 on Proterozoic sedimentary or metasedimentary sequences in western and Central Africa and South America. Some stratigraphic results have been established: (1) five formations have been dated of the Lower Proterozoic; (2) a long sedimentation gap occurs, mainly in western Africa and in some regions of Central Africa and South America between nearly 1600 and 1100 Ma; (3) the upper Riphean assemblages of stromatolites have been dated and compared to those of the Eurasian craton; (4) two main glacial events have been dated, the first one placed at ca. 950 Ma, the second during the Vendian, at ca. 650-620 Ma; (5) it can be stated that, when applied to Precambrian sequences, all stratigraphic methods must be used together. (Auth.)

  13. Micro and Macroscale Drivers of Nutrient Concentrations in Urban Streams in South, Central and North America.

    Loiselle, Steven A; Gasparini Fernandes Cunha, Davi; Shupe, Scott; Valiente, Elsa; Rocha, Luciana; Heasley, Eleanore; Belmont, Patricia Pérez; Baruch, Avinoam

    Global metrics of land cover and land use provide a fundamental basis to examine the spatial variability of human-induced impacts on freshwater ecosystems. However, microscale processes and site specific conditions related to bank vegetation, pollution sources, adjacent land use and water uses can have important influences on ecosystem conditions, in particular in smaller tributary rivers. Compared to larger order rivers, these low-order streams and rivers are more numerous, yet often under-monitored. The present study explored the relationship of nutrient concentrations in 150 streams in 57 hydrological basins in South, Central and North America (Buenos Aires, Curitiba, São Paulo, Rio de Janeiro, Mexico City and Vancouver) with macroscale information available from global datasets and microscale data acquired by trained citizen scientists. Average sub-basin phosphate (P-PO4) concentrations were found to be well correlated with sub-basin attributes on both macro and microscales, while the relationships between sub-basin attributes and nitrate (N-NO3) concentrations were limited. A phosphate threshold for eutrophic conditions (>0.1 mg L-1 P-PO4) was exceeded in basins where microscale point source discharge points (eg. residential, industrial, urban/road) were identified in more than 86% of stream reaches monitored by citizen scientists. The presence of bankside vegetation covaried (rho = -0.53) with lower phosphate concentrations in the ecosystems studied. Macroscale information on nutrient loading allowed for a strong separation between basins with and without eutrophic conditions. Most importantly, the combination of macroscale and microscale information acquired increased our ability to explain sub-basin variability of P-PO4 concentrations. The identification of microscale point sources and bank vegetation conditions by citizen scientists provided important information that local authorities could use to improve their management of lower order river ecosystems.

  14. Atmospheric circulation associated with extreme generalized frosts persistence in central-southern South America

    Mueller, Gabriela V. [Centro de Investigaciones Cientificas y Transferencia de Tecnologia a la Produccion, Diamante (CICYTTTP-CONICET), Diamante, Entre Rios (Argentina); Berri, Guillermo J. [Servicio Meteorologico Nacional - CONICET, Buenos Aires (Argentina)

    2012-03-15

    Generalized frosts (GF) in central-southern South America have a strong impact due to their spatial extension, and they are especially important when they become persistent. This paper aims at identifying the atmospheric circulation features that determine the extreme GF persistence, i.e. very persistent and without persistence, and the differences between them, during the 1961-1990 winters. Since the GF without persistence group outnumbers the other one, two subgroups are composed with events selected from winters with maximum and minimum frequency of GF occurrence, respectively. Additionally, the individual event of July 1988 within the very persistent GF group is analyzed due to its exceptional persistence. GF persistence is mainly conditioned by two large-scale dynamic factors. One is the Rossby wave train propagation across the Pacific Ocean, and the other one is the location with respect to the continent and the magnitude of the confluence in the jet entrance region in subtropical latitudes. A predominantly meridional Rossby wave train propagation with a confluence region to the west of the continent prior to the event favors GF with intermediate (null) persistence depending on the greater (lesser) jet acceleration. This is conditioned by the magnitude of the confluence, which, in turn, depends on the disposition of the wave train propagation pattern. Instead, an essentially zonal propagation with a confluence region to the east of the continent favors the GF persistence for several days, yet if there is no confluence the event does not persist. The greatest persistence of an event combines the confluence/diffluence of the jet entrance/exit region, which depends on the disposition with respect to the continent of the zonally propagating Rossby wave trains. (orig.)

  15. Emerging deforestation trends in tropical dry forests ecoregions of Mexico and Central America

    Portillo, C. A.; Cao, G.; Smith, V.

    2015-12-01

    Neotropical dry forests (TDF) have experienced an unprecedented deforestation that is leading to the loss of tropical biodiversity at a rapid pace, but information on deforestation dynamics in TDF is scarce. In this study, we present a sub-continental and national level assessment of TDF loss patterns in Mexico and Central America at high spatial and temporal resolution using remote sensing and GIS technologies. We used the Global Forest Change (GFC) dataset published by Hansen et al. (2013) which shows results from time-series analysis of Landsat images in characterizing global forest extent and change from 2000 through 2013. We analyzed forest loss within and around mapped TDF cover mapped by Portillo-Quintero et al. 2010. In order to minimize errors in source data, we overlaid a 25 x 25 km grid on top of the regional dataset and conducted a cell by cell and country by country inspection at multiple scales using high resolution ancillary data. We identified trends in the clustering of space-time TDF deforestation data using ArcGIS, categorizing trends in: new, consecutive, intensifying, persistent, diminishing, sporadic, oscillating and historical hotspots (high frequency of deforestation events) and cold spots (low frequency of deforestation). In general, the region is experiencing less frequent deforestation events with a higher number of intensifying and new cold spots across TDF landscapes. However, an important number of intensifying and persistent hotspots exist so no general trend in forest loss was detected for the period 2001-2013, except for El Salvador which shows a significant decreasing trend in forest loss. Mexico, Nicaragua, Honduras and Guatemala are the major sources of intensifying, persistent and new deforestation hot spots. These were identified in the southern pacific coast and the Yucatan Peninsula in Mexico, northwestern Guatemala, both western and eastern Honduras and around Lake Nicaragua in Nicaragua.

  16. Phylogenetics of Ogyges Kaup and the biogeography of Nuclear Central America (Coleoptera, Passalidae)

    Cano, Enio B.; Schuster, Jack C.; Morrone, Juan J.

    2018-01-01

    Abstract A phylogenetic morphological analysis of the genus Ogyges Kaup, distributed in Nuclear Central America, from Chiapas, Mexico, to northwestern Nicaragua was undertaken. Five species of Proculejus Kaup, distributed north of the Isthmus of Tehuantepec in Mexico, were selected as outgroup. Ogyges was recovered as monophyletic with three species groups: championi, laevissimus, and crassulus. Each species group shows a distinct, generally allopatric distribution. The O. championi species group, with ten species, is distributed in the Maya block, more specifically in the mountainous system north of the Motozintla-Comaltitlán fault in Chiapas, and north of the dry valleys of the Cuilco and Motagua rivers in Guatemala. The two remaining species groups are distributed in the Chortis block. The O. laevissimus species group, including seven species, ranges mostly along the Pacific Volcanic Chain from Guatemala to El Salvador, and from southeastern Honduras to the northwestern area of Nicaragua. The O. crassulus species group, with ten species, is distributed from northeastern Guatemala (Merendón) to northern Honduras. The Isthmus of Tehuantepec in Mexico, the Motagua-Cuilco and Motozintla-Comaltitlán sutures zones in Chiapas and Guatemala, the lowland valleys of Colón and Comalí rivers between Nicaragua and Honduras (or, perhaps, the northern suture of the Siuna Terrane in Nicaragua), the Guayape fault system in Honduras, and the intricate dry valleys of Ulúa-Chamelecón-Olancho in Honduras, are hypothesized to have acted as barriers that affected the geographical distribution of Ogyges, as well as probably other montane organisms. PMID:29674874

  17. Offspring production in three freshwater crab species (Brachyura: Pseudothelphusidae from the Amazon region and Central America

    Ingo S. Wehrtmann

    2010-01-01

    Full Text Available Freshwater crabs are an important component of the fauna of limnic environments, and out of the two true freshwater crab families present in the Neotropics, Pseudothelphusidae is the most diverse. Considering the lack of information regarding reproductive features of neotropical freshwater crabs, we studied, for the first time, the fecundity and the presence of juveniles carried by females of two pseudothelphusids from the Amazon region - Kingsleya latifrons (Randall, 1840 and Kingsleya ytupora Magalhães, 1986 - and one from Central America - Potamocarcinus magnus (Rathbun, 1896. The two Kingsleya species produced relatively few (56-114 and large eggs (1.9-3.7 mm, typical for species with an abbreviated or direct development. Recently produced eggs were substantially larger in K. latifrons (mean 2.83 mm when compared to those of K. ytupora (mean 1.87 mm; however, at the end of the embryogenesis, mean egg diameter was similar in both species. Therefore, it is assumed that hatchlings in both species should have a similar size. A brief description of attached juveniles of K. ytupora is provided. The number of juveniles varied between 30 (K. ytupora and 179 (P. magnus; two size groups of juveniles were found, which indicates that the offspring cling to their mother for a prolonged period of time. There was no significant loss of eggs and juveniles; it is assumed that parental care diminishes the loss of their offspring. We compiled the available information of reproductive aspects from freshwater crabs: egg diameter was in the range of 2-3 mm, independent of female size and fecundity, and reported egg number varied between 9 and 417 eggs.

  18. [Physical and chemical characterization of industrial nixtamalized corn flour for human consumption in Central America].

    Bressani, R; Turcios, J C; Reyes, L; Mérida, R

    2001-09-01

    The objective of this study was the characterization of industrial nixtamalized maize flour for human consumption and which are marketed in Central America for some selected physical and chemical properties which may contribute to food composition information and help nutrition and micronutrient fortification programs. A total of 12 brands purchased in triplicate were obtained from supermarkets in Guatemala, El Salvador and Honduras. These samples were kept under refrigeration until analyzed. The physical parameters measured and results were the following: particle size with most samples having a high percentage of particles greater than 60 mesh, pH (5.4-7.5), water absorption index (WAI) (3.4-4.0 g gel/g sample), water soluble index (WSI) (4.8-7.8 g/100 g) and flour density (0.410-0.547 g/ml). The differences were statistically significant for all parameters measured, except for WAI. The chemical characteristics included, moisture, protein, fat, ash and dietetic fiber. Differences between flour samples were statistically significant except for fat content. Protein content was low, ranging between 6.7-8.1 g/100 g and total dietary fiber varied between 7.7-12.0 g/100 g. The samples were analyzed for phytic acid with a variation from 632 to 903 mg/100 g, with statistical significant differences. The samples were also analyzed for total and soluble (pH 7.5) iron, phosphorus, calcium, potassium, zinc, copper, manganese, and magnesium. The difference in the iron and calcium content between flour samples were statistically significant. The physical and chemical variability found between flour samples of nixtamalized maize was relatively high and it is recommended to establish quality standards through raw material and process standardization for greater effectiveness of nutrition programs and activities on micronutrient fortification which may be pursued in the future.

  19. [Agrarian movements, development alternatives and food security in Central America: scenarios of transition].

    Rodriguez Rojas, R

    1991-01-01

    This article, based on personal experiences with a network of organizations of small and medium agricultural producers in Central America, aims to present the views of peasant organizations concerning agrarian problems in the region. The 3 major sections of work define the place of peasant agriculture in the traditional agrarian structure and the new problems resulting from the structural adjustment programs of the 1980s; separately describe the new peasant movements emerging in Honduras, El Salvador, Nicaragua, Costa Rica, and Panama, identifying common themes an efforts at international collaboration; and explore the positions of the peasant organizations on the optimal strategies for agricultural development and agrarian change. Agriculture remains the backbone of the Central American economies. But because the economic model in the region is 1 of accumulation characterized by dependency, concentration of capital, and social marginalization, the agrarian structure is at the basis of social tensions. Efforts to develop peasant agriculture and to give small producers access to marketing and credit services have been weak and sporadic. The new peasant movements are less inclined than those of the past to employ tactics of confrontation in their efforts to secure access to land and better working conditions. The new movement is the expression of small market producers sometimes grouped into associations who are oriented to production of basic foodstuffs for the internal market. A new concern with adaptation and negotiation is evident. The new organizations have in common a belief in their ability to propose new solutions to regional problems. Their views are founded on a positive assessment of the ability of peasant agriculture to produce food and add dynamism to the regional economy after barriers to credit, technological progress, and modernization in general are removed. Signs of increased cooperation are evident between peasant organizations and other groups

  20. NATURAL AND ANTHROPIC RISK STUDIES IN FOUR DECADES IN THE GEOGRAPHICAL JOURNAL OF CENTRAL AMERICA (1974 - 2015)

    Quesada-Román, Adolfo

    2017-01-01

    The aim of this work is to identify the influence of the international and national epistemological trends and the techniques in the risk management of disasters (RMD) in Costa Rica. To do this, the journal papers of the Geographical Journal of Central America between 1974 and 2015 were analyzed -114 included topics related to natural and anthropogenic risks. They were classified into eight thematic classes: seismic hazards, volcanic hazards, slope processes hazards, hydrometeorological hazar...

  1. Medicinal Plants from North and Central America and the Caribbean Considered Toxic for Humans: The Other Side of the Coin

    Alonso-Castro, Angel Josabad; Domínguez, Fabiola; Ruiz-Padilla, Alan Joel; Campos-Xolalpa, Nimsi; Zapata-Morales, Juan Ramón; Carranza-Alvarez, Candy; Maldonado-Miranda, Juan Jose

    2017-01-01

    The consumption of medicinal plants has notably increased over the past two decades. People consider herbal products as safe because of their natural origin, without taking into consideration whether these plants contain a toxic principle. This represents a serious health problem. A bibliographic search was carried out using published scientific material on native plants from Mexico, Central America, and the Caribbean, which describe the ethnobotanical and toxicological information of medicin...

  2. Method to Determine Appropriate Source Models of Large Earthquakes Including Tsunami Earthquakes for Tsunami Early Warning in Central America

    Tanioka, Yuichiro; Miranda, Greyving Jose Arguello; Gusman, Aditya Riadi; Fujii, Yushiro

    2017-01-01

    Large earthquakes, such as the Mw 7.7 1992 Nicaragua earthquake, have occurred off the Pacific coasts of El Salvador and Nicaragua in Central America and have generated distractive tsunamis along these coasts. It is necessary to determine appropriate fault models before large tsunamis hit the coast. In this study, first, fault parameters were estimated from the W-phase inversion, and then an appropriate fault model was determined from the fault parameters and scaling relationships with a dept...

  3. Accommodation of missing shear strain in the Central Walker Lane, western North America: Constraints from dense GPS measurements

    Bormann, Jayne M.; Hammond, William C.; Kreemer, Corné; Blewitt, Geoffrey

    2016-04-01

    We present 264 new interseismic GPS velocities from the Mobile Array of GPS for Nevada Transtension (MAGNET) and continuous GPS networks that measure Pacific-North American plate boundary deformation in the Central Walker Lane. Relative to a North America-fixed reference frame, northwestward velocities increase smoothly from ∼4 mm/yr in the Basin and Range province to 12.2 mm/yr in the central Sierra Nevada resulting in a Central Walker Lane deformation budget of ∼8 mm/yr. We use an elastic block model to estimate fault slip and block rotation rates and patterns of deformation from the GPS velocities. Right-lateral shear is distributed throughout the Central Walker Lane with strike-slip rates generally Bodie Hills, Carson Domain, and Mina Deflection are between 1-4°/Myr, lower than published paleomagnetic rotation rates, suggesting that block rotation rates have decreased since the Late to Middle Miocene.

  4. Characterization of individuals at high risk of developing melanoma in Latin America: bases for genetic counseling in melanoma.

    Puig, Susana; Potrony, Miriam; Cuellar, Francisco; Puig-Butille, Joan Anton; Carrera, Cristina; Aguilera, Paula; Nagore, Eduardo; Garcia-Casado, Zaida; Requena, Celia; Kumar, Rajiv; Landman, Gilles; Costa Soares de Sá, Bianca; Gargantini Rezze, Gisele; Facure, Luciana; de Avila, Alexandre Leon Ribeiro; Achatz, Maria Isabel; Carraro, Dirce Maria; Duprat Neto, João Pedreira; Grazziotin, Thais C; Bonamigo, Renan R; Rey, Maria Carolina W; Balestrini, Claudia; Morales, Enrique; Molgo, Montserrat; Bakos, Renato Marchiori; Ashton-Prolla, Patricia; Giugliani, Roberto; Larre Borges, Alejandra; Barquet, Virginia; Pérez, Javiera; Martínez, Miguel; Cabo, Horacio; Cohen Sabban, Emilia; Latorre, Clara; Carlos-Ortega, Blanca; Salas-Alanis, Julio C; Gonzalez, Roger; Olazaran, Zulema; Malvehy, Josep; Badenas, Celia

    2016-07-01

    CDKN2A is the main high-risk melanoma-susceptibility gene, but it has been poorly assessed in Latin America. We sought to analyze CDKN2A and MC1R in patients from Latin America with familial and sporadic multiple primary melanoma (SMP) and compare the data with those for patients from Spain to establish bases for melanoma genetic counseling in Latin America. CDKN2A and MC1R were sequenced in 186 Latin American patients from Argentina, Brazil, Chile, Mexico, and Uruguay, and in 904 Spanish patients. Clinical and phenotypic data were obtained. Overall, 24 and 14% of melanoma-prone families in Latin America and Spain, respectively, had mutations in CDKN2A. Latin American families had CDKN2A mutations more frequently (P = 0.014) than Spanish ones. Of patients with SMP, 10% of those from Latin America and 8.5% of those from Spain had mutations in CDKN2A (P = 0.623). The most recurrent CDKN2A mutations were c.-34G>T and p.G101W. Latin American patients had fairer hair (P = 0.016) and skin (P < 0.001) and a higher prevalence of MC1R variants (P = 0.003) compared with Spanish patients. The inclusion criteria for genetic counseling of melanoma in Latin America may be the same criteria used in Spain, as suggested in areas with low to medium incidence, SMP with at least two melanomas, or families with at least two cases among first- or second-degree relatives.Genet Med 18 7, 727-736.

  5. Evaluating Ultraviolet Radiation Exposures Determined from TOMS Satellite Data at Sites of Amphibian Declines in Central and South America

    Middleton, Elizabeth M.; Smith, David E. (Technical Monitor)

    2000-01-01

    Many amphibian species have experienced substantial population declines, or have disappeared altogether, during the last several decades at a number of amphibian census sites in Central and South America. This study addresses the use of satellite-derived trends in solar ultraviolet-B (UV-B; 280-320 nm) radiation exposures at these sites over the last two decades, and is intended to demonstrate a role for satellite observations in determining whether UV-B radiation is a contributing factor in amphibian declines. UV-B radiation levels at the Earth's surface were derived from the Total Ozone Mapping Spectrometer (TOMS) satellite data, typically acquired daily since 1979. These data were used to calculate the daily erythemal (sunburning) UV-B, or UV-B(sub ery), exposures at the latitude, longitude, and elevation of each of 20 census sites. The annually averaged UV-B(sub ery) dose, as well as the maximum values, have been increasing in both Central and South America, with higher levels received at the Central American sites. The annually averaged UV-B(sub ery) exposures increased significantly from 1979-1998 at all 11 Central American sites examined (r(exp 2) = 0.60 - 0.79; P= 6750 J/sq m*d) to the annual UV-B(sub ery) total has increased from approx. 5% to approx. 15% in Central America over the 19 year period, but actual daily exposures for each species are unknown. Synergy among UV-B radiation and other factors, especially those associated with alterations of water chemistry (e.g., acidification) in aqueous habitats is discussed. These findings justify further research concerning whether UV-B(sub ery) radiation plays a role in amphibian population declines and extinctions.

  6. Alternative (G-16v2) Ground Motion Prediction Equations for the Central and Eastern North America

    Graizer, V.

    2016-12-01

    Introduced is the ground motion prediction equations model for the Central and Eastern North America that represents an alternative more physically justified approach to ground motion attenuation modeling then previous Graizer (2016) G-16 model. The new model has a bilinear slope of R-1 within 70 km from the fault with a slope of R-0.5 at larger distances corresponding to the geometrical spreading of body and surface waves. The new (G-16v2) model is based in part on the NGA-East database for the horizontal peak ground acceleration and 5%-damped pseudo spectral acceleration (SA) and also on comparisons with the Western U.S. data and ground motion simulations. Based on data, I estimated the average slope of the distance attenuation within the 50-70 km distance from the fault to be -1.0 at most of the frequencies supporting regular geometrical spreading of body waves. Multiple inversions are performed to estimate apparent (combined intrinsic and scattering) attenuation of SA amplitudes from the NGA-East database for incorporation into the model. These estimates demonstrate a difference between seismological Q(f) and the above mentioned attenuation factor that I recommend calling QSA(f). I adjusted previously developed site correction which was based on multiple runs of representative VS30 (time-averaged shear-wave velocity in the upper 30 m) profiles through SHAKE-type equivalent-linear codes. Site amplifications are calculated relative to the hard rock definition used in nuclear industry (VS=2800 m/s). These improvements resulted in a modest reduction in standard deviation in the new G-16v2 relative to the G-16 model. The number of model predictors is limited to a few measurable parameters: moment magnitude M, closest distance to fault rupture plane Rrup, VS30, and apparent attenuation factor QSA(f). The model is applicable for the stable continental regions and covers the following range: 4.0≤M≤8.5, 0≤Rrup≤1000 km, 450≤VS30≤2800 m/s and frequencies 0.1

  7. Food Security and Extreme Events: Evidence from Smallholder Farmers in Central America

    Saborio-Rodriguez, M.; Alpizar, F.; Harvey, C.; Martinez, R.; Vignola, R.; Viguera, B.; Capitan, T.

    2016-12-01

    Extreme weather events, which are expected to increase in magnitude and frequency due to climate change, are one of the main threats for smallholder farmers in Central America. Using a rich dataset from carefully selected subsistence farm households, we explore the determinants and severity of food insecurity resulting from extreme hydrometeorological hazards. In addition, we analyze farmerś coping strategies. Our analysis sheds light over food insecurity as an expression of vulnerability in a region that is expected to be increasingly exposed to extreme events and in a population already stressed by poverty and lack of opportunities. Regarding food insecurity, multivariate analyses indicate that education, having at least one migrant in the household, labor allocation, number of plots, and producing coffee are determinants of the probability of experiencing lack of food after an extreme weather event. Once the household is lacking food, the duration of the episode is related to access to credit, number of plots, producing coffee, ownership of land and gender of the head of the household. This results are in line with previous literature on the determinants of food insecurity in particular, and vulnerability, in general. Our dataset also allows us to analyze coping strategies. Households experiencing lack of food after an extreme weather event report mainly changes in their habits, as decreasing the amount of food consumed (54%) and modifying their diet (35%). A low proportion of household (between 10% and 15%, depending on the nature of the event) use their assets, by redirecting their savings, migrating, and selling items from the house. Asking money or food from family and friends or from an organization is reported for 4% of the households. This general results are connected to the specific coping strategies related to damages in crops, which are explored in detail. Our results indicate that there are patterns among the household experiencing lack of food

  8. Energy integration experiences at the Europe, at the Nordic countries and at the Central America: considerations relevant to the South America integration process; Experiencias de integracao energetica na Europa, nos paises nordicos e na America Central: consideracoes relevantes ao processo de integracao Sul-Americana

    Campos, Adriana Fiorotti; Andreza, Fernanda Marques Pereira; Soares, Jeferson Borghetti; Pinheiro, Maria Fernanda Bacile; Oliveira, Ricardo Gorini de [Empresa de Pesquisa Energetica (EPE), Rio de Janeiro, RJ (Brazil)], Emails: adriana.campos@epe.gov.br, fernanda.andreza@epe.gov.br; jeferson.soares@epe.gov.br, maria.pinheiro, ricardo.gorini@epe.gov.br

    2010-07-01

    In view of institutional/contractual regulatory problems at the South America, some experiences of energy integration at the electrical sectors and natural gas (Nordic countries. European Union and Central America), identifying related vantages and advantageous. Besides, there is an attempt of characterization of the process step of energy integration, and the fitting of regions in these steps, observing that the process of energy integration in the South America it is found in a initial step yet if it is considered the used methodology by the Colombian enterprise Interconexion Electrica S.A.E.S.P. - ISA (2007)

  9. Phenology and recruitment of Caryocar costaricense (Caryocaceae, an endemic tree species of Southern Central America

    Silvia Solís

    2009-09-01

    Full Text Available Basic aspects of the reproductive biology are largely unknown for most tropical tree species, although they are important elements to understand the impacts of anthropogenic activities as logging and forest fragmentation on these populations. In this study, data are presented on leaf and reproductive phenology, fruit production and seedling demography of a population of an endemic tree species of Southern Central America, Caryocar costaricense. This species has been affected by selective logging and forest fragmentation of its habitat. Phenology was studied by observation of 15-22 tree crowns during two reproductive periods (2003 and 2005. Circular plots were established around 11 adult trees to count the number of fallen fruits and seedlings during three years (2003, 2004, 2005. Although reproductive phenology is restricted to the short dry season in this species, seed germination occurred year-round. Fruit and seedling production shows a strong inter-individual variation within the study populations, with two large trees producing nearly 50%-70% of the fruits and seedlings during two years. Most of the seeds that fall beneath the tree crown are covered by litterfall or removed by fauna. We found evidence that many of these seeds become part of a seed bank in the forest floor. Because of the observed reproductive dominance of few large trees in these populations, we propose that selective logging on reproductive trees can severely impact the recruitment of this species. Rev. Biol. Trop. 57 (3: 771-780. Epub 2009 September 30.Los aspectos básicos de la biología reproductiva de árboles tropicales son en su mayoría desconocidos, aunque son conocimientos esenciales para entender el impacto de actividades antropogénicas como la tala selectiva y la fragmentación de bosques. En este estudio se presentan datos sobre la fenología foliar y reproductiva, la producción de frutos, y la demografía de plántulas de una población de Caryocar

  10. Central Bank independence in Latin America La independencia de la Banca Central en América Latina

    Junguito Bonnet Roberto

    1996-06-01

    Full Text Available This article describes the origin and evolution of the central banks of Argentina, Brazil, Chile, Colombia, Mexico, and Venezuela, and analyzes their respective institutional structures. It also studies the contribution of the central bank to stabilization and the problems for maintaining this independence into the future.Este artículo describe el origen y la evolución de los Bancos Centrales de Argentina, Brasil, Chile, Colombia, México y Venezuela, y analiza sus respectivas estructruras institucionales. También estudia la contribución de la banca central a la estabilización y los problemas para que esta independencia se mantenga en el futuro.

  11. Accelerated Evolution and Functional Divergence of the Dim Light Visual Pigment Accompanies Cichlid Colonization of Central America.

    Hauser, Frances E; Ilves, Katriina L; Schott, Ryan K; Castiglione, Gianni M; López-Fernández, Hernán; Chang, Belinda S W

    2017-10-01

    Cichlids encompass one of the most diverse groups of fishes in South and Central America, and show extensive variation in life history, morphology, and colouration. While studies of visual system evolution in cichlids have focussed largely on the African rift lake species flocks, Neotropical cichlids offer a unique opportunity to investigate visual system evolution at broader temporal and geographic scales. South American cichlid colonization of Central America has likely promoted accelerated rates of morphological evolution in Central American lineages as they encountered reduced competition, renewed ecological opportunity, and novel aquatic habitats. To investigate whether such transitions have influenced molecular evolution of vision in Central American cichlids, we sequenced the dim-light rhodopsin gene in 101 Neotropical cichlid species, spanning the diversity of the clade. We find strong evidence for increased rates of evolution in Central American cichlid rhodopsin relative to South American lineages, and identify several sites under positive selection in rhodopsin that likely contribute to adaptation to different photic environments. We expressed a Neotropical cichlid rhodopsin protein invitro for the first time, and found that while its spectral tuning properties were characteristic of typical vertebrate rhodopsin pigments, the rate of decay of its active signalling form was much slower, consistent with dim light adaptation in other vertebrate rhodopsins. Using site-directed mutagenesis combined with spectroscopic assays, we found that a key amino acid substitution present in some Central American cichlids accelerates the rate of decay of active rhodopsin, which may mediate adaptation to clear water habitats. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  12. Medicinal plants used in the traditional management of diabetes and its sequelae in Central America: A review.

    Giovannini, Peter; Howes, Melanie-Jayne R; Edwards, Sarah E

    2016-05-26

    Globally 387 million people currently have diabetes and it is projected that this condition will be the 7th leading cause of death worldwide by 2030. As of 2012, its total prevalence in Central America (8.5%) was greater than the prevalence in most Latin American countries and the population of this region widely use herbal medicine. The aim of this study is to review the medicinal plants used to treat diabetes and its sequelae in seven Central American countries: Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua and Panama. We conducted a literature review and extracted from primary sources the plant use reports in traditional remedies that matched one of the following disease categories: diabetes mellitus, kidney disease, urinary problems, skin diseases and infections, cardiovascular disease, sexual dysfunctions, visual loss, and nerve damage. Use reports were entered in a database and data were analysed in terms of the highest number of use reports for diabetes management and for the different sequelae. We also examined the scientific evidence that might support the local uses of the most reported species. Out of 535 identified species used to manage diabetes and its sequelae, 104 species are used to manage diabetes and we found in vitro and in vivo preclinical experimental evidence of hypoglycaemic effect for 16 of the 20 species reported by at least two sources. However, only seven of these species are reported in more than 3 studies: Momordica charantia L., Neurolaena lobata (L.) R. Br. ex Cass., Tecoma stans (L.) Juss. ex Kunth, Persea americana Mill., Psidium guajava L., Anacardium occidentale L. and Hamelia patens Jacq. Several of the species that are used to manage diabetes in Central America are also used to treat conditions that may arise as its consequence such as kidney disease, urinary problems and skin conditions. This review provides an overview of the medicinal plants used to manage diabetes and its sequelae in Central America and of

  13. Chronic kidney disease of nontraditional etiology in Central America: a provisional epidemiologic case definition for surveillance and epidemiologic studies.

    Lozier, Matthew; Turcios-Ruiz, Reina Maria; Noonan, Gary; Ordunez, Pedro

    2016-11-01

    SYNOPSIS Over the last two decades, experts have reported a rising number of deaths caused by chronic kidney disease (CKD) along the Pacific coast of Central America, from southern Mexico to Costa Rica. However, this specific disease is not associated with traditional causes of CKD, such as aging, diabetes, or hypertension. Rather, this disease is a chronic interstitial nephritis termed chronic kidney disease of nontraditional etiology (CKDnT). According to the Pan American Health Organization (PAHO) mortality database, there are elevated rates of deaths related to kidney disease in many of these countries, with the highest rates being reported in El Salvador and Nicaragua. This condition has been identified in certain agricultural communities, predominantly among male farmworkers. Since CKD surveillance systems in Central America are under development or nonexistent, experts and governmental bodies have recommended creating standardized case definitions for surveillance purposes to monitor and characterize this epidemiological situation. A group of experts from Central American ministries of health, the U.S. Centers for Disease Control and Prevention (CDC), and PAHO held a workshop in Guatemala to discuss CKDnT epidemiologic case definitions. In this paper, we propose that CKD in general be identified by the standard definition internationally accepted and that a suspect case of CKDnT be defined as a person age CKDnT is defined as a suspect case with the same findings confirmed three or more months later.

  14. Plants used in the traditional medicine of Mesoamerica (Mexico and Central America) and the Caribbean for the treatment of obesity.

    Alonso-Castro, Angel Josabad; Domínguez, Fabiola; Zapata-Morales, Juan Ramón; Carranza-Álvarez, Candy

    2015-12-04

    Obesity is a worldwide medical concern. New ethnobotanical information regarding the antiobesity effect of medicinal plants has been obtained in the last 30 years in response to socio-demographic changes and high-fat diets became common. This review provides a summary of medicinal plants used in Mexico, Central America and the Caribbean for the empirical treatment of obesity in terms of ethnobotany, toxicity, pharmacology, conservation status, trade and chemistry. Bibliographic investigation was performed by analyzing recognized books, undergraduate and postgraduate theses and peer-reviewed scientific articles, consulting worldwide accepted scientific databases from the last four decades. Medicinal plants used for the treatment of obesity were classified in two categories: (1) plants with pharmacological evidence and (2) plants without pharmacological evidence. A total of 139 plant species, belonging to 61 families, native to Mexico, Central America and the Caribbean that are used for the empirical treatment of obesity were recorded. From these plants, 33 were investigated in scientific studies, and 106 plants lacked scientific investigation. Medicinal plants were experimentally studied in vitro (21 plants) and in vivo (16 plants). A total of 4 compounds isolated from medicinal plants used for the empirical treatment of obesity have been tested in vitro (2 compounds) and in vivo (4 compounds) studies. No clinical trials on obese subjects (BMI>30 kg/m(2)) have been performed using the medicinal plants cited in this review. There are no herbal-based products approved in Mexico for the treatment of obesity. There are a limited number of scientific studies published on medicinal plants from Mexico, Central America and the Caribbean used for the treatment of obesity. This review highlights the need to perform pharmacological, phytochemical, toxicological and ethnobotanical studies with medicinal flora to obtain new antiobesity agents. Copyright © 2015 Elsevier Ireland

  15. From Forgotten Area to Platform of Expansion. Central America in the Cartographic Representations and English Naval Projects (1680-1742

    Guadalupe Pinzón Ríos

    2018-05-01

    Full Text Available The aim of this article is to analyze how the English became interested in Central America and planned to use it as a platform to extend their naval activities from the Atlantic to the Pacific. They revealed their intentions in their accounts of their voyages and in their maps. Those accounts and maps became instruments of power to justify their advances, and by means of them, they tried to make their presence permanent. Is important to analyze this process because the English used this method again in other areas.

  16. Mid-term evaluation of the NRECA (National Rural Electric Cooperative Association) Central America Rural Electrification Support Program (CARES)

    Perlack, R.D. (Oak Ridge National Lab., TN (USA)); Jones, H.G. (Oak Ridge Associated Universities, Inc., TN (USA)); Garcia, A. III (Texas A and M Univ., College Station, TX (USA). Dept. of Agricultural Engineering); Flores, E. (Flores (Edgar), Guatemala City (Guatemala))

    1990-09-01

    Oak Ridge National Laboratory was requested by the Regional Office for Central America and Panama to conduct a mid-term evaluation of the Cares Project, which is being implemented by the National Rural Electric Cooperative Association. This evaluation was conducted over a three week period by a four person team. Overall, the project has had numerous successes and is highly valued by local counterpart utilities and USAID Missions. Notwithstanding the significant results of the project, changes can be made in certain operating procedures and in the direction of some programmatic activities that can lead to an even more effective project.

  17. Genetic Differentiation within the Puccinia triticina Population in South America and Comparison with the North American Population Suggests Common Ancestry and Intercontinental Migration

    Leaf rust, caused by Puccinia triticina is the most prevalent and widespread disease of wheat in South America. The objective of this study was to determine the number of genetically differentiated groups of P. triticina that are currently present in South America, and to compare the South American ...

  18. Non-invasive genetic monitoring of wild central chimpanzees.

    Mimi Arandjelovic

    Full Text Available BACKGROUND: An assessment of population size and structure is an important first step in devising conservation and management plans for endangered species. Many threatened animals are elusive, rare and live in habitats that prohibit directly counting individuals. For example, a well-founded estimate of the number of great apes currently living in the wild is lacking. Developing methods to obtain accurate population estimates for these species is a priority for their conservation management. Genotyping non-invasively collected faecal samples is an effective way of evaluating a species' population size without disruption, and can also reveal details concerning population structure. METHODOLOGY/PRINCIPAL FINDINGS: We opportunistically collected wild chimpanzee faecal samples for genetic capture-recapture analyses over a four-year period in a 132 km(2 area of Loango National Park, Gabon. Of the 444 samples, 46% yielded sufficient quantities of DNA for genotyping analysis and the consequent identification of 121 individuals. Using genetic capture-recapture, we estimate that 283 chimpanzees (range: 208-316 inhabited the research area between February 2005 and July 2008. Since chimpanzee males are patrilocal and territorial, we genotyped samples from males using variable Y-chromosome microsatellite markers and could infer that seven chimpanzee groups are present in the area. Genetic information, in combination with field data, also suggested the occurrence of repeated cases of intergroup violence and a probable group extinction. CONCLUSIONS/SIGNIFICANCE: The poor amplification success rate resulted in a limited number of recaptures and hence only moderate precision (38%, measured as the entire width of the 95% confidence interval, but this was still similar to the best results obtained using intensive nest count surveys of apes (40% to 63%. Genetic capture-recapture methods applied to apes can provide a considerable amount of novel information on

  19. Inflation Performance and Constitutional Central Bank Independence. Evidence from Latin America and the Caribbean

    Eva Gutiérrez

    2004-01-01

    This paper explores the relationship between the constitutional entrenchment of central bank independence and inflation performance. Empirical studies for developing countries have not found a relationship between central bank independence, proxied by the "de jure" independence established in the central bank law, and inflation. We argue that the constitution is likely to be better enforced than ordinary statutes owing to its higher legal rank. Our empirical analysis finds that in a sample of...

  20. Exploration of a rare population of Chinese chestnut in North America: stand dynamics, health and genetic relationships.

    Miller, Amy C; Woeste, Keith E; Anagnostakis, Sandra L; Jacobs, Douglass F

    2014-10-20

    With the transport of plants around the globe, exotic species can readily spread disease to their native relatives; however, they can also provide genetic resistance to those relatives through hybrid breeding programmes. American chestnut (Castanea dentata) was an abundant tree species in North America until its decimation by introduced chestnut blight. To restore chestnut in North America, efforts are ongoing to test putative blight-resistant hybrids of Castanea dentata and Chinese chestnut (Castanea mollissima), but little is known about the ecology of C. mollissima. In a forest in northeastern USA in which C. mollissima has become established, we explored questions of stand dynamics, health and genetic relationships of C. mollissima offspring to an adjacent parent orchard. We found that C. mollissima was adapted and randomly distributed among native species in this relatively young forest. The genetics of the C. mollissima population compared with its parents indicated little effect of selection pressure as each of the parent trees contributed at least one offspring. The ease with which this exotic species proliferated calls to question why C. mollissima is rare elsewhere in forests of North America. It is likely that a time window of low animal predation allowed seedlings to establish, and the shallow soil at this site limited the maximum forest canopy height, permitting the characteristically short-statured C. mollissima to avoid suppression. Our results indicate that because C. mollissima exhibited pioneer species characteristics, hybrids between C. mollissima and C. dentata have the potential to be successful pioneer species of future forests in North America, and we challenge the paradigm that exotic tree species are wholly detrimental to native biodiversity. We contend that exotic tree species should be assessed not only by their level of threat to native species, but also by their potential positive impacts on ecosystems via hybrid breeding programmes

  1. Introduction: seismology and earthquake engineering in Mexico and Central and South America.

    Espinosa, A.F.

    1982-01-01

    The results from seismological studies that are used by the engineering community are just one of the benefits obtained from research aimed at mitigating the earthquake hazard. In this issue of Earthquake Information Bulletin current programs in seismology and earthquake engineering, seismic networks, future plans and some of the cooperative programs with different internation organizations are described by Latin-American seismologists. The article describes the development of seismology in Latin America and the seismological interest of the OAS. -P.N.Chroston

  2. Medicinal Plants from North and Central America and the Caribbean Considered Toxic for Humans: The Other Side of the Coin.

    Alonso-Castro, Angel Josabad; Domínguez, Fabiola; Ruiz-Padilla, Alan Joel; Campos-Xolalpa, Nimsi; Zapata-Morales, Juan Ramón; Carranza-Alvarez, Candy; Maldonado-Miranda, Juan Jose

    2017-01-01

    The consumption of medicinal plants has notably increased over the past two decades. People consider herbal products as safe because of their natural origin, without taking into consideration whether these plants contain a toxic principle. This represents a serious health problem. A bibliographic search was carried out using published scientific material on native plants from Mexico, Central America, and the Caribbean, which describe the ethnobotanical and toxicological information of medicinal plants empirically considered to be toxic. A total of 216 medicinal plants belonging to 77 families have been reported as toxic. Of these plants, 76 had been studied, and 140 plants lacked studies regarding their toxicological effects. The toxicity of 16 plants species has been reported in clinical cases, particularly in children. From these plants, deaths have been reported with the consumption of Chenopodium ambrosioides , Argemone mexicana , and Thevetia peruviana . In most of the cases, the principle of the plant responsible for the toxicity is unknown. There is limited information about the toxicity of medicinal plants used in Mexico, Central America, and the Caribbean. More toxicological studies are necessary to contribute information about the safe use of the medicinal plants cited in this review.

  3. Medicinal Plants from North and Central America and the Caribbean Considered Toxic for Humans: The Other Side of the Coin

    Ruiz-Padilla, Alan Joel; Campos-Xolalpa, Nimsi; Carranza-Alvarez, Candy; Maldonado-Miranda, Juan Jose

    2017-01-01

    The consumption of medicinal plants has notably increased over the past two decades. People consider herbal products as safe because of their natural origin, without taking into consideration whether these plants contain a toxic principle. This represents a serious health problem. A bibliographic search was carried out using published scientific material on native plants from Mexico, Central America, and the Caribbean, which describe the ethnobotanical and toxicological information of medicinal plants empirically considered to be toxic. A total of 216 medicinal plants belonging to 77 families have been reported as toxic. Of these plants, 76 had been studied, and 140 plants lacked studies regarding their toxicological effects. The toxicity of 16 plants species has been reported in clinical cases, particularly in children. From these plants, deaths have been reported with the consumption of Chenopodium ambrosioides, Argemone mexicana, and Thevetia peruviana. In most of the cases, the principle of the plant responsible for the toxicity is unknown. There is limited information about the toxicity of medicinal plants used in Mexico, Central America, and the Caribbean. More toxicological studies are necessary to contribute information about the safe use of the medicinal plants cited in this review. PMID:29234446

  4. Medicinal Plants from North and Central America and the Caribbean Considered Toxic for Humans: The Other Side of the Coin

    Angel Josabad Alonso-Castro

    2017-01-01

    Full Text Available The consumption of medicinal plants has notably increased over the past two decades. People consider herbal products as safe because of their natural origin, without taking into consideration whether these plants contain a toxic principle. This represents a serious health problem. A bibliographic search was carried out using published scientific material on native plants from Mexico, Central America, and the Caribbean, which describe the ethnobotanical and toxicological information of medicinal plants empirically considered to be toxic. A total of 216 medicinal plants belonging to 77 families have been reported as toxic. Of these plants, 76 had been studied, and 140 plants lacked studies regarding their toxicological effects. The toxicity of 16 plants species has been reported in clinical cases, particularly in children. From these plants, deaths have been reported with the consumption of Chenopodium ambrosioides, Argemone mexicana, and Thevetia peruviana. In most of the cases, the principle of the plant responsible for the toxicity is unknown. There is limited information about the toxicity of medicinal plants used in Mexico, Central America, and the Caribbean. More toxicological studies are necessary to contribute information about the safe use of the medicinal plants cited in this review.

  5. Method to Determine Appropriate Source Models of Large Earthquakes Including Tsunami Earthquakes for Tsunami Early Warning in Central America

    Tanioka, Yuichiro; Miranda, Greyving Jose Arguello; Gusman, Aditya Riadi; Fujii, Yushiro

    2017-08-01

    Large earthquakes, such as the Mw 7.7 1992 Nicaragua earthquake, have occurred off the Pacific coasts of El Salvador and Nicaragua in Central America and have generated distractive tsunamis along these coasts. It is necessary to determine appropriate fault models before large tsunamis hit the coast. In this study, first, fault parameters were estimated from the W-phase inversion, and then an appropriate fault model was determined from the fault parameters and scaling relationships with a depth dependent rigidity. The method was tested for four large earthquakes, the 1992 Nicaragua tsunami earthquake (Mw7.7), the 2001 El Salvador earthquake (Mw7.7), the 2004 El Astillero earthquake (Mw7.0), and the 2012 El Salvador-Nicaragua earthquake (Mw7.3), which occurred off El Salvador and Nicaragua in Central America. The tsunami numerical simulations were carried out from the determined fault models. We found that the observed tsunami heights, run-up heights, and inundation areas were reasonably well explained by the computed ones. Therefore, our method for tsunami early warning purpose should work to estimate a fault model which reproduces tsunami heights near the coast of El Salvador and Nicaragua due to large earthquakes in the subduction zone.

  6. Methodological and Practical Considerations for DevelopingMultiproject Baselines for Electric Power and Cement Industry Projects inCentral America

    Murtishaw, Scott; Sathaye, Jayant; Galitsky, Christina; Dorion,Kristel

    2004-09-02

    The Lawrence Berkeley National Laboratory (Berkeley Lab) andthe Center for Sustainable Development in the Americas (CSDA) conductedtechnical studies and organized two training workshops to developcapacity in Central America for the evaluation of climate changeprojects. This paper describes the results of two baseline case studiesconducted for these workshops, one for the power sector and one for thecement industry, that were devised to illustrate certain approaches tobaseline setting. Multiproject baseline emission rates (BERs) for themain Guatemalan electricity grid were calculated from 2001 data. Inrecent years, the Guatemalan power sector has experienced rapid growth;thus, a sufficient number of new plants have been built to estimateviable BERs. We found that BERs for baseload plants offsetting additionalbaseload capacity ranged from 0.702 kgCO2/kWh (using a weighted averagestringency) to 0.507 kgCO2/kWh (using a 10th percentile stringency),while the baseline for plants offsetting load-followingcapacity is lowerat 0.567 kgCO2/kWh. For power displaced from existing load-followingplants, the rate is higher, 0.735 kgCO2/kWh, as a result of the age ofsome plants used for meeting peak loads and the infrequency of their use.The approved consolidated methodology for the Clean Development Mechanismyields a single rate of 0.753 kgCO2/kWh. Due to the relatively smallnumber of cement plants in the region and the regional nature of thecement market, all of Central America was chosen as the geographicboundary for setting cement industry BERs. Unfortunately, actualoperations and output data were unobtainable for most of the plants inthe region, and many data were estimated. Cement industry BERs rangedfrom 205 kgCO2 to 225 kgCO2 per metric ton of cement.

  7. Comparison of population genetic patterns in two widespread freshwater mussels with contrasting life histories in western North America.

    Mock, K E; Brim Box, J C; Chong, J P; Furnish, J; Howard, J K

    2013-12-01

    We investigate population genetic structuring in Margaritifera falcata, a freshwater mussel native to western North America, across the majority of its geographical range. We find shallow rangewide genetic structure, strong population-level structuring and very low population diversity in this species, using both mitochondrial sequence and nuclear microsatellite data. We contrast these patterns with previous findings in another freshwater mussel species group (Anodonta californiensis/A. nuttalliana) occupying the same continental region and many of the same watersheds. We conclude that differences are likely caused by contrasting life history attributes between genera, particularly host fish requirements and hermaphroditism. Further, we demonstrate the occurrence of a 'hotspot' for genetic diversity in both groups of mussels, occurring in the vicinity of the lower Columbia River drainage. We suggest that stream hierarchy may be responsible for this pattern and may produce similar patterns in other widespread freshwater species. © 2013 John Wiley & Sons Ltd.

  8. Xylella fastidiosa CoDiRO strain associated with the olive quick decline syndrome in southern Italy belongs to a clonal complex of the subspecies pauca that evolved in Central America.

    Marcelletti, Simone; Scortichini, Marco

    2016-12-01

    Xylella fastidiosa, a xylem-limited bacterium transmitted by xylem-fluid-feeding Hemiptera insects, causes economic losses of both woody and herbaceous plant species. A Xyl. fastidiosa subsp. pauca strain, namely CoDiRO, was recently found to be associated with the 'olive quick decline syndrome' in southern Italy (i.e. Apulia region). Recently, some Xyl. fastidiosa strains intercepted in France from Coffea spp. plant cuttings imported from Central and South America were characterized. The introduction of infected plant material from Central America in Apulia was also postulated even though an ad hoc study to confirm this hypothesis is lacking. In the present study, we assessed the complete and draft genome of 27 Xyl. fastidiosa strains. Through a genome-wide approach, we confirmed the occurrence of three subspecies within Xyl. fastidiosa, namely fastidiosa, multiplex and pauca, and demonstrated the occurrence of a genetic clonal complex of four Xyl. fastidiosa strains belonging to subspecies pauca which evolved in Central America. The CoDiRO strain displayed 13 SNPs when compared with a strain isolated in Costa Rica from Coffea sp. and 32 SNPs when compared with two strains obtained from Nerium oleander in Costa Rica. These results support the close relationships of the two strains. The four strains in the clonal complex contain prophage-like genes in their genomes. This study strongly supports the possibility of the introduction of Xyl. fastidiosa in southern Italy via coffee plants grown in Central America. The data also stress how the current global circulation of agricultural commodities potentially threatens the agrosystems worldwide.

  9. Rainforest understory beetles of the Neotropics, Mizotrechus Bates 1872, a generic synopsis with descriptions of new species from Central America and northern South America (Coleoptera, Carabidae, Perigonini).

    Erwin, Terry L

    2011-01-01

    Information on the single previously described species, Mizotrechus novemstriatus Bates 1872 (type locality: Brazil - Amazonas, Tefé), is updated and 17 new species for the genus from Nicaragua, Costa Rica, Panamá, Colombia, Venezuela, and Guyane are described. The species records in the literature and on determined specimens in some collections of Mizotrechus novemstriatus Bates from Central America are not that species; currently, Mizotrechus novemstriatus is known only from its type locality in Amazonian Brazil. For the new species described, their known general distributions are as follows: Mizotrechus batesisp. n. (Guyane), Mizotrechus bellorumsp. n. (Guyane), Mizotrechus bruleisp. n. (Guyane), Mizotrechus belevederesp. n. (Guyane), Mizotrechus costaricensissp. n. (Costa Rica), Mizotrechus dalensisp. n. (Guyane), Mizotrechus edithpiafaesp. n. (provenance unknown), Mizotrechus fortunensissp. n. (Panamá), Mizotrechus gorgona. sp. n. (Colombia), Mizotrechus grossussp. n. (Guyane), Mizotrechus jefesp. n. (Panamá), Mizotrechus marielaforetaesp. n. (Guyane), Mizotrechus minutussp. n. (Guyane), Mizotrechus neblinensissp. n. (Guyane, Venezuela), Mizotrechus poirierisp. n. (Guyane), and Mizotrechus woldaisp. n. (Panamá). Long-term use of flight intercept traps in Guyane provided so many new species that apparently the use of FITs is the way to collect adults of this taxon, previously known from very few specimens. Many more species of this genus can be expected to be discovered throughout the Neotropics; the present contribution is a preliminary synopsis with identification key and adult images of all known species. Likely numerous species are yet to be discovered throughout tropical climes.

  10. The mobility of students in Central America: in search of hegemonic knowledge?

    Edorta CAMINO ESTURO

    2018-01-01

    Full Text Available The dynamics of Central American students’ mobility is characterized by one-way mobility to the Western countries, as centers of hegemonic knowledge, especially the United States. However, there has been an increase in academic mobility to Cuba, which suggests the emergence of an alternative space and a counterbalance to this trend. Instead, mobility towards the Central American region is domestic and peripheral, with more intraregional than foreign contributions, standing on the sidelines of university centers of scientific production.

  11. Pleistocene to holocene expansion of the black-belt cichlid in Central America, Vieja maculicauda (Teleostei: Cichlidae.

    Caleb D McMahan

    Full Text Available The distributions of many Northern Hemisphere organisms have been influenced by fluctuations in sea level and climatic conditions during Pleistocene interglacial periods. These cycles are associated with range contraction and refugia for northern-distributed organisms as a response to glaciers. However, lower sea levels in the tropics and sub-tropics created available habitat for expansion of the ranges of freshwater organisms. The goal of this study was to use ecological niche modeling to test the hypothesis of north to south range expansion of Vieja maculicauda associated with Pleistocene glacial cycles. Understanding the biogeography of this widespread species may help us better understand the geology and interconnectivity of Central American freshwaters. Occurrence data for V. maculicauda was based on georeferencing of all museum records of specimens recovered from FishNet2. General patterns of phylogeographic structure were assessed with mtDNA. Present day niche models were generated and subsequently projected onto paleoclimatic maps of the region during the Last Interglacial, Last Glacial Maximum, and mid-Holocene. Phylogenetic analysis of mtDNA sequence data showed no phylogeographic structure throughout the range of this widespread species. Present day niche models were congruent with the observed distribution of V. maculicauda in Central America. Results showed a lack of suitable freshwater habitat in northern Central America and Mexico during the Last Interglacial, with greatest range expansion during the Last Glacial Maximum and mid-Holocene. Results support the hypothesis of a north to south range expansion of V. maculicauda associated with glacial cycles. The wide distribution of this species compared to other closely related cichlids indicates the latter did not respond to the degree of V. maculicauda in expansion of their distributions. Future work aimed at comparisons with other species and modeling of future climatic scenarios

  12. Chronic kidney disease of nontraditional etiology in Central America: a provisional epidemiologic case definition for surveillance and epidemiologic studies

    Matthew Lozier

    Full Text Available SYNOPSIS Over the last two decades, experts have reported a rising number of deaths caused by chronic kidney disease (CKD along the Pacific coast of Central America, from southern Mexico to Costa Rica. However, this specific disease is not associated with traditional causes of CKD, such as aging, diabetes, or hypertension. Rather, this disease is a chronic interstitial nephritis termed chronic kidney disease of nontraditional etiology (CKDnT. According to the Pan American Health Organization (PAHO mortality database, there are elevated rates of deaths related to kidney disease in many of these countries, with the highest rates being reported in El Salvador and Nicaragua. This condition has been identified in certain agricultural communities, predominantly among male farmworkers. Since CKD surveillance systems in Central America are under development or nonexistent, experts and governmental bodies have recommended creating standardized case definitions for surveillance purposes to monitor and characterize this epidemiological situation. A group of experts from Central American ministries of health, the U.S. Centers for Disease Control and Prevention (CDC, and PAHO held a workshop in Guatemala to discuss CKDnT epidemiologic case definitions. In this paper, we propose that CKD in general be identified by the standard definition internationally accepted and that a suspect case of CKDnT be defined as a person age < 60 years with CKD, without type 1 diabetes mellitus, hypertensive diseases, and other well-known causes of CKD. A probable case of CKDnT is defined as a suspect case with the same findings confirmed three or more months later.

  13. The genetics of shovel shape in maxillary central incisors in man.

    Blanco, R; Chakraborty, R

    1976-03-01

    From dental casts of 94 parent-offspring and 127 full-sib pairs, sampled from two Chilean populations, shovelling indices are computed to measure the degree of shovelling of maxillary central incisors quantitatively. Genetic correlations are computed to determine the role of genetic factors in explaining the variation in this trait. Assuming only hereditary factors to be responsible for the transmission of shovel shape, 68% of total variability is ascribed to the additive effect of genes.

  14. The Tonalá fault in southeastern Mexico: Evidence that the Central America forearc sliver is not being detached?

    Guzman-Speziale, M.; Molina-Garza, R. S.

    2012-12-01

    The Tonalá fault is a NW-SE oriented feature that flanks the Chiapas Massif on its southwestern side. Several authors coincide that the fault originally developed as a right-lateral structure in the Jurassic, but was reactivated as a left-lateral fault in the Miocene. Seismicity along the fault is low: Only one earthquake with magnitude 5.0 or larger is reported along the Tonalá fault in the years 1964 to present. Fault-plane solutions determined by the Mexican Seismological Survey for earthquakes along the fault show left-lateral, strike-slip faulting. The Tonalá fault lies on the northwestern continuation of the Central America volcanic arc. The volcanic arc is the site of medium-sized (magnitudes up to 6.5) shallow, right-lateral, strike-slip earthquakes. This has led several workers to propose that the forearc sliver is being detached from the Caribbean plate along the arc, moving northward. GPS studies have confirmed relative motion between the Chortis block and the forearc sliver. Recent and current motion along the Tonalá fault is in contradiction with motion and detachment of the forearc sliver along the Central America volcanic arc. Left-lateral motion along it cannot accomodate northwest displacement of the forearc sliver. Motion of the Central America forearc would require NW directed compression between the continental shelf of Chiapas and the forearc itself, which is not observed. Therefore, either another fault (or faults) accomodates right-lateral motion and detachment of the forearc sliver, or the sliver is not being detached and relative motion between the forearc sliver and the Chortis block corresponds to displacement of the latter. We suggest that, as proposed by previous authors, the Tonalá fault is instead part of a fault system that runs from the state of Oaxaca (the Valle Nacional fault), forming an arc concave to the northeast, and running perpendicular to the maximum slope of subduction in the area.

  15. A new species of the genus Mahanarva Distant, 1909 (Hemiptera: Cercopoidea: Cercopidae, with a key to the species from Central America and Mexico

    Ulises Castro–Valderrama

    2018-02-01

    Full Text Available The genus Mahanarva Distant, 1909 (Hemiptera: Cercopoidea: Cercopidae currently includes two subgenera: Mahanarva Distant, 1909 with 38 species and six subspecies, and Ipiranga Fennah, 1968 with nine species. The Manaharva species are all from the Americas, and a few species are important pests in pasture grasses and sugarcane. There are no reports of any Manaharva species from North America, including Mexico and areas to the north. Here, a new species is described from Mexico and a key to the species of Mahanarva from Central America and Mexico is proposed.

  16. Higher Education in Central America: Historical Foundations for Its Future Projection.

    Arriaza, Ricardo Sol

    1996-01-01

    Three trends in Central American higher education are examined in historical context: (1) inertia from lack of mobility, bureaucracy, and corporate influence; (2) elitism as a response to budgetary constraints; and (3) attempts to increase responsiveness to educational needs and demands. Issues examined include earlier attempts at change, slow…

  17. Pricing, subsidies, and the poor : demand for improved water services in Central America

    Walker, Ian; Ordonez, Fidel; Serrano, Pedro; Halpern, Jonathan

    2000-01-01

    Reformulating tariff and subsidy policies is central to improving water and sanitation services in developing countries. The traditional model of state enterprise service provision, coupled with residential tariffs set well below the cost of service, has generally delivered unsatisfactory results. Low internal generation of funds has impeded expansion of networks into poor communities and ...

  18. Pesticide Avoidance Behavior in Anopheles albimanus, a Malaria Vectorin Central and South America

    1995-07-11

    Hatched lines delineate the overall distribution of AOQPheles albjmanys. Fig. 2. UPGMA phenogram from Nei·s (1978) unbiased genetic distance ix...by the unweighted pair-group method arithmetic averaging ( UPGMA ) to produce the phenogram. Polyacrylamide gel electrophoresis Polyacrylamide gel...distance was clustered by the unweighted pair group method ( UPGMA ) to produce the phenogram as shown in Figure 2. Phenograms proouced by using other

  19. Comparative genetic diversity in a sample of pony breeds from the U.K. and North America: a case study in the conservation of global genetic resources.

    Winton, Clare L; Plante, Yves; Hind, Pamela; McMahon, Robert; Hegarty, Matthew J; McEwan, Neil R; Davies-Morel, Mina C G; Morgan, Charly M; Powell, Wayne; Nash, Deborah M

    2015-08-01

    Most species exist as subdivided ex situ daughter population(s) derived from a single original group of individuals. Such subdivision occurs for many reasons both natural and manmade. Traditional British and Irish pony breeds were introduced to North America (U.S.A. and Canada) within the last 150 years, and subsequently equivalent breed societies were established. We have analyzed selected U.K. and North American equivalent pony populations as a case study for understanding the relationship between putative source and derived subpopulations. Diversity was measured using mitochondrial DNA and a panel of microsatellite markers. Genetic signatures differed between the North American subpopulations according to historical management processes. Founder effect and stochastic drift was apparent, particularly pronounced in some breeds, with evidence of admixture of imported mares of different North American breeds. This demonstrates the importance of analysis of subpopulations to facilitate understanding the genetic effects of past management practices and to lead to informed future conservation strategies.

  20. Climatic change on the Gulf of Fonseca (Central America) using two-step statistical downscaling of CMIP5 model outputs

    Ribalaygua, Jaime; Gaitán, Emma; Pórtoles, Javier; Monjo, Robert

    2018-05-01

    A two-step statistical downscaling method has been reviewed and adapted to simulate twenty-first-century climate projections for the Gulf of Fonseca (Central America, Pacific Coast) using Coupled Model Intercomparison Project (CMIP5) climate models. The downscaling methodology is adjusted after looking for good predictor fields for this area (where the geostrophic approximation fails and the real wind fields are the most applicable). The method's performance for daily precipitation and maximum and minimum temperature is analysed and revealed suitable results for all variables. For instance, the method is able to simulate the characteristic cycle of the wet season for this area, which includes a mid-summer drought between two peaks. Future projections show a gradual temperature increase throughout the twenty-first century and a change in the features of the wet season (the first peak and mid-summer rainfall being reduced relative to the second peak, earlier onset of the wet season and a broader second peak).

  1. Rainforest understory beetles of the Neotropics: Mizotrechus Bates 1872, a generic synopsis with descriptions of new species from Central America and northern South America (Coleoptera, Carabidae, Perigonini

    Terry Erwin

    2011-11-01

    Full Text Available Information on the single previously described species, Mizotrechus novemstriatus Bates 1872 (type locality: Brazil – Amazonas, Tefé, is updated and 17 new species for the genus from Nicaragua, Costa Rica, Panamá, Colombia, Venezuela, and Guyane are described. The species records in the literature and on determined specimens in some collections of M. novemstriatus Bates from Central America are not that species; currently, M. novemstriatus is known only from its type locality in Amazonian Brazil. For the new species described, their known general distributions are as follows: Mizotrechus batesi sp. n. (Guyane, Mizotrechus bellorum sp. n. (Guyane, Mizotrechus brulei sp. n. (Guyane, Mizotrechus belevedere sp. n. (Guyane, Mizotrechus costaricensis sp. n. (Costa Rica, Mizotrechus dalensi sp. n. (Guyane, Mizotrechus edithpiafae sp. n. (provenance unknown, Mizotrechus fortunensis sp. n. (Panamá, Mizotrechus gorgona. sp. n. (Colombia, Mizotrechus grossus sp. n. (Guyane, Mizotrechus jefe sp. n. (Panamá, Mizotrechus marielaforetae sp. n. (Guyane, Mizotrechus minutus sp. n. (Guyane, Mizotrechus neblinensis sp. n. (Guyane, Venezuela, Mizotrechus poirieri sp. n. (Guyane, and Mizotrechus woldai sp. n. (Panamá. Long-term use of flight intercept traps in Guyane provided so many new species that apparently the use of FITs is the way to collect adults of this taxon, previously known from very few specimens. Many more species of this genus can be expected to be discovered throughout the Neotropics; the present contribution is a preliminary synopsis with identification key and adult images of all known species. Likely numerous species are yet to be discovered throughout tropical climes.

  2. Women's Networking and Alliance Building in Post-War Central America

    Ilja Luciak

    2002-01-01

    Ilja A. Luciak examines the efforts of Central American women, from both the political left and right in El Salvador and Nicaragua, to build alliances across ideological boundaries in order to effectively advocate women's rights during the transition toward political systems rooted in democratic governance and gender equality. He discusses coalition-building in El Salvador and Nicaragua in order to demonstrate the progress that has been made and the key challenges confronting the leaders of t...

  3. Improving Regional Security in Central America: Military Engagement Options for Nicaragua

    2002-12-01

    of Disasters) Guatemala, Guatemala. Secretaria de Integracion Economica Centroamericana. 68 Smith, Peter H. 2000. Talons of the Eagle: Dynamics of...for reviewing instruction, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection...an essential role in the stability and security of the Central American sub region. The de -stabilizing influence of Sandinista policies in the 1980s

  4. The use of genetics for the management of a recovering population: temporal assessment of migratory peregrine falcons in North America.

    Jeff A Johnson

    2010-11-01

    Full Text Available Our ability to monitor populations or species that were once threatened or endangered and in the process of recovery is enhanced by using genetic methods to assess overall population stability and size over time. This can be accomplished most directly by obtaining genetic measures from temporally-spaced samples that reflect the overall stability of the population as given by changes in genetic diversity levels (allelic richness and heterozygosity, degree of population differentiation (F(ST and D(EST, and effective population size (N(e. The primary goal of any recovery effort is to produce a long-term self-sustaining population, and these genetic measures provide a metric by which we can gauge our progress and help make important management decisions.The peregrine falcon in North America (Falco peregrinus tundrius and anatum was delisted in 1994 and 1999, respectively, and its abundance will be monitored by the species Recovery Team every three years until 2015. Although the United States Fish and Wildlife Service makes a distinction between tundrius and anatum subspecies, our genetic results based on eleven microsatellite loci suggest limited differentiation that can be attributed to an isolation by distance relationship and warrant no delineation of these two subspecies in its northern latitudinal distribution from Alaska through Canada into Greenland. Using temporal samples collected at Padre Island, Texas during migration (seven temporal time periods between 1985-2007, no significant differences in genetic diversity or significant population differentiation in allele frequencies between time periods were observed and were indistinguishable from those obtained from tundrius/anatum breeding locations throughout their northern distribution. Estimates of harmonic mean N(e were variable and imprecise, but always greater than 500 when employing multiple temporal genetic methods.These results, including those from simulations to assess the power of

  5. The greenhouse effect in central North America: If not now, when?

    Karl, T.R.; Heim, R.R. Jr.

    1991-01-01

    The consistency of the predictions of the Intergovernmental Panel on Climate Change (IPCC) with observed data are discussed, with reference to statistical models and Monte-Carlo simulation. Climate change projections for North America predict increases of temperature of 2-4 degree C by 2030. Analysis of the climate record over the last 95 years has failed to indicate statistically significant changes. Statistical models using auto-regressive moving-average techniques have been developed to calculate the likelihood that the greenhouse signal may have been masked by natural climate variability, and have indicated that there is a high probability that changes have been masked. However, some projections, such as the increase in ratio of winter to summer precipitation, should have been detected. The probability of not detecting temperature changes as large as projected range from 5% for large temperature increases to 65% for smaller increases, depending on the scenario. These results suggest that the projections of large increases in temperature of 3-4 degree C are inconsistent with past observation. It will likely take 15-20 years beyond 1990 before summer temperature increases would be detected, and over 40 years before summer precipitation decreases would be detected, assuming IPCC projections are basically correct. 13 refs., 3 figs., 4 tabs

  6. Do Bananas Have a Culture? United Fruit Company Colonies in Central America 1900-1960

    Atalia Shragai

    2014-06-01

    Full Text Available This article is concerned with the processes underlying the development of the unique identifications and culture which evolved among the First Class Workers of the United Fruit Company - the vast majority of whom were citizens of the United States, working alongside Europeans and Central Americans - during the first half of the twentieth century. Examining the social and cultural practices widespread among the Company’s colonies, I trace the nature of the ‘Banana Culture’, a term coined by the members of this group.

  7. Mapping the expansion of coyotes (Canis latrans across North and Central America

    James W. Hody

    2018-05-01

    Full Text Available The geographic distribution of coyotes (Canis latrans has dramatically expanded since 1900, spreading across much of North America in a period when most other mammal species have been declining. Although this considerable expansion has been well documented at the state/provincial scale, continent-wide descriptions of coyote spread have portrayed conflicting distributions for coyotes prior to the 1900s, with popularly referenced anecdotal accounts showing them restricted to the great plains, and more obscure, but data-rich accounts suggesting they ranged across the arid west. To provide a scientifically credible map of the coyote’s historical range (10,000–300 BP and describe their range expansion from 1900 to 2016, we synthesized archaeological and fossil records, museum specimens, peer-reviewed reports, and records from wildlife management agencies. Museum specimens confirm that coyotes have been present in the arid west and California throughout the Holocene, well before European colonization. Their range in the late 1800s was undistinguishable from earlier periods, and matched the distribution of non-forest habitat in the region. Coyote expansion began around 1900 as they moved north into taiga forests, east into deciduous forests, west into costal temperate rain forests, and south into tropical rainforests. Forest fragmentation and the extirpation of larger predators probably enabled these expansions. In addition, hybridization with wolves (C. lupus, C. lycaon, and/or C. rufus and/or domestic dogs has been documented in the east, and suspected in the south. Our detailed account of the original range of coyotes and their subsequent expansion provides the core description of a large scale ecological experiment that can help us better understand the predator-prey interactions, as well as evolution through hybridization.

  8. Hydro, wind and solar power as a base for a 100% renewable energy supply for South and Central America.

    Larissa de Souza Noel Simas Barbosa

    Full Text Available Power systems for South and Central America based on 100% renewable energy (RE in the year 2030 were calculated for the first time using an hourly resolved energy model. The region was subdivided into 15 sub-regions. Four different scenarios were considered: three according to different high voltage direct current (HVDC transmission grid development levels (region, country, area-wide and one integrated scenario that considers water desalination and industrial gas demand supplied by synthetic natural gas via power-to-gas (PtG. RE is not only able to cover 1813 TWh of estimated electricity demand of the area in 2030 but also able to generate the electricity needed to fulfil 3.9 billion m3 of water desalination and 640 TWhLHV of synthetic natural gas demand. Existing hydro dams can be used as virtual batteries for solar and wind electricity storage, diminishing the role of storage technologies. The results for total levelized cost of electricity (LCOE are decreased from 62 €/MWh for a highly decentralized to 56 €/MWh for a highly centralized grid scenario (currency value of the year 2015. For the integrated scenario, the levelized cost of gas (LCOG and the levelized cost of water (LCOW are 95 €/MWhLHV and 0.91 €/m3, respectively. A reduction of 8% in total cost and 5% in electricity generation was achieved when integrating desalination and power-to-gas into the system.

  9. Hydro, wind and solar power as a base for a 100% renewable energy supply for South and Central America.

    Barbosa, Larissa de Souza Noel Simas; Bogdanov, Dmitrii; Vainikka, Pasi; Breyer, Christian

    2017-01-01

    Power systems for South and Central America based on 100% renewable energy (RE) in the year 2030 were calculated for the first time using an hourly resolved energy model. The region was subdivided into 15 sub-regions. Four different scenarios were considered: three according to different high voltage direct current (HVDC) transmission grid development levels (region, country, area-wide) and one integrated scenario that considers water desalination and industrial gas demand supplied by synthetic natural gas via power-to-gas (PtG). RE is not only able to cover 1813 TWh of estimated electricity demand of the area in 2030 but also able to generate the electricity needed to fulfil 3.9 billion m3 of water desalination and 640 TWhLHV of synthetic natural gas demand. Existing hydro dams can be used as virtual batteries for solar and wind electricity storage, diminishing the role of storage technologies. The results for total levelized cost of electricity (LCOE) are decreased from 62 €/MWh for a highly decentralized to 56 €/MWh for a highly centralized grid scenario (currency value of the year 2015). For the integrated scenario, the levelized cost of gas (LCOG) and the levelized cost of water (LCOW) are 95 €/MWhLHV and 0.91 €/m3, respectively. A reduction of 8% in total cost and 5% in electricity generation was achieved when integrating desalination and power-to-gas into the system.

  10. The use of genetics for the management of a recovering population: temporal assessment of migratory peregrine falcons in North America

    Johnson, Jeff A.; Talbot, Sandra L.; Sage, George K.; Burnham, Kurt K.; Brown, Joseph W.; Maechtle, Tom L.; Seegar, William S.; Yates, Michael A.; Anderson, Bud; Mindell, David P.

    2010-01-01

    Background:Our ability to monitor populations or species that were once threatened or endangered and in the process of recovery is enhanced by using genetic methods to assess overall population stability and size over time. This can be accomplished most directly by obtaining genetic measures from temporally-spaced samples that reflect the overall stability of the population as given by changes in genetic diversity levels (allelic richness and heterozygosity), degree of population differentiation (FST and DEST), and effective population size (Ne). The primary goal of any recovery effort is to produce a long-term self-sustaining population, and these measures provide a metric by which we can gauge our progress and help make important management decisions. Methodology/Principal Findings:The peregrine falcon in North America (Falco peregrinus tundrius and anatum) was delisted in 1994 and 1999, respectively, and its abundance will be monitored by the species Recovery Team every three years until 2015. Although the United States Fish and Wildlife Service makes a distinction between tundrius and anatum subspecies, our genetic results based on eleven microsatellite loci, including those from Brown et al. (2007), suggest no differentiation and warrant delineation of a subspecies in its northern latitudinal distribution from Alaska through Canada into Greenland. Using temporal samples collected at Padre Island, Texas during migration (seven temporal time periods between 1985-2007), no significant differences in genetic diversity or significant population differentiation in allele frequencies between time periods were observed and were indistinguishable from those obtained from tundrius/anatum breeding locations throughout their northern distribution. Estimates of harmonic mean Ne were variable and imprecise, but always greater than 500 when employing multiple temporal genetic methods. These results, including those from simulations to assess the power of each method to

  11. Genetic structure of local populations of Lutzomyia longipalpis (Diptera: Psychodidae) in central Colombia.

    Munstermann, L E; Morrison, A C; Ferro, C; Pardo, R; Torres, M

    1998-01-01

    Lutzomyia longipalpis (Lutz & Neiva), the sand fly vector of American visceral leishmaniasis in the New World tropics, has a broad but discontinuous geographical distribution from southern Mexico to Argentina. A baseline for population genetic structure and genetic variability for this species was obtained by analyzing 5 local, peridomestic populations at the approximate center of its distribution, the Magdalena River Valley of central Colombia. Three populations of L. longipalpis from El Callejón, a small rural community, were compared with 2 populations from neighboring areas 12 and 25 km distant for genetic variation at 15 isoenzyme loci. The mean heterozygosity ranged from 11 to 16%, with 1.2 to 2.3 alleles detected per locus. Nei's genetic distances among the populations were very low, ranging from 0.001 to 0.007. Gene flow estimates based on FST indicated high levels of gene flow among local L. longipalpis populations, with minimal population substructuring.

  12. A GPS and modelling study of deformation in northern Central America

    Rodriguez, M.; DeMets, C.; Rogers, R.; Tenorio, C.; Hernandez, D.

    2009-09-01

    We use GPS measurements at 37 stations in Honduras and El Salvador to describe active deformation of the western end of the Caribbean Plate between the Motagua fault and Central American volcanic arc. All GPS sites located in eastern Honduras move with the Caribbean Plate, in accord with geologic evidence for an absence of neotectonic deformation in this region. Relative to the Caribbean Plate, the other stations in the study area move west to west-northwest at rates that increase gradually from 3.3 +/- 0.6 mm yr-1 in central Honduras to 4.1 +/- 0.6 mm yr-1 in western Honduras to as high as 11-12 mm yr-1 in southern Guatemala. The site motions are consistent with slow westward extension that has been inferred by previous authors from the north-striking grabens and earthquake focal mechanisms in this region. We examine the factors that influence the regional deformation by comparing the new GPS velocity field to velocity fields predicted by finite element models (FEMs) that incorporate the regional plate boundary faults and known plate motions. Our modelling suggests that the obliquely convergent (~20°) direction of Caribbean-North American Plate motion relative to the Motagua fault west of 90°W impedes the ENE-directed motion of the Caribbean Plate in southern Guatemala, giving rise to extension in southern Guatemala and western Honduras. The FEM predictions agree even better with the measured velocities if the plate motion west of the Central American volcanic arc is forced to occur over a broad zone rather than along a single throughgoing plate boundary fault. Our analysis confirms key predictions of a previous numerical model for deformation in this region, and also indicates that the curvature of the Motagua fault causes significant along-strike changes in the orientations of the principal strain-rate axes in the fault borderlands, in accord with earthquake focal mechanisms and conclusions reached in a recent synthesis of the structural and morphologic data

  13. CO{sub 2} emissions, energy usage, and output in Central America

    Apergis, Nicholas [Department of Banking and Financial Management, University of Piraeus, Karaoli and Dimitriou 80, Piraeus, ATTIKI 18534 (Greece); Payne, James E. [College of Arts and Sciences, Illinois State University, Campus Box 4100, Normal, IL 61790-4100 (United States)

    2009-08-15

    This study extends the recent work of Ang (2007) [Ang, J.B., 2007. CO{sub 2} emissions, energy consumption, and output in France. Energy Policy 35, 4772-4778] in examining the causal relationship between carbon dioxide emissions, energy consumption, and output within a panel vector error correction model for six Central American countries over the period 1971-2004. In long-run equilibrium energy consumption has a positive and statistically significant impact on emissions while real output exhibits the inverted U-shape pattern associated with the Environmental Kuznets Curve (EKC) hypothesis. The short-run dynamics indicate unidirectional causality from energy consumption and real output, respectively, to emissions along with bidirectional causality between energy consumption and real output. In the long-run there appears to be bidirectional causality between energy consumption and emissions. (author)

  14. Lithospheric expression of geological units in central and eastern North America from full waveform tomography

    Yuan, Huaiyu; French, Scott; Cupillard, Paul; Romanowicz, Barbara

    2014-09-01

    The EarthScope TA deployment has provided dense array coverage throughout the continental US and with it, the opportunity for high resolution 3D seismic velocity imaging of both lithosphere and asthenosphere in the continent. Building upon our previous long-period waveform tomographic modeling in North America, we present a higher resolution 3D isotropic and radially anisotropic shear wave velocity model of the North American lithospheric mantle, constructed tomographically using the spectral element method for wavefield computations and waveform data down to 40 s period. The new model exhibits pronounced spatial correlation between lateral variations in seismic velocity and anisotropy and major tectonic units as defined from surface geology. In the center of the continent, the North American craton exhibits uniformly thick lithosphere down to 200-250 km, while major tectonic sutures of Proterozoic age visible in the surface geology extend down to 100-150 km as relatively narrow zones of distinct radial anisotropy, with Vsv >Vsh. Notably, the upper mantle low velocity zone is present everywhere under the craton between 200 and 300 km depth. East of the continental rift margin, the lithosphere is broken up into a series of large, somewhat thinner (150 km) high velocity blocks, which extend laterally 200-300 km offshore into the Atlantic Ocean. Between the craton and these deep-rooted blocks, we find a prominent narrow band of low velocities that roughly follows the southern and eastern Laurentia rift margin and extends into New England. We suggest that the lithosphere along this band of low velocities may be thinned due to the combined effects of repeated rifting processes and northward extension of the hotspot related Bermuda low-velocity channel across the New England region. We propose that the deep rooted high velocity blocks east of the Laurentia margin represent the Proterozoic Gondwanian terranes of pan-African affinity, which were captured during the Rodinia

  15. Temporal patterns and geographic heterogeneity of Zika virus (ZIKV outbreaks in French Polynesia and Central America

    Ying-Hen Hsieh

    2017-03-01

    Full Text Available Background Zika virus (ZIKV transmission has been reported in 67 countries/territories in the Oceania region and the Americas since 2015, prompting the World Health Organization (WHO to declare ZIKV as a Public Health Emergency of International Concern in February 2016, due to its strong association with medical complications such as microcephaly and Guillain–Barré Syndrome (GBS. However, a substantial gap in knowledge still exists regarding differing temporal pattern and potential of transmission of ZIKV in different regions of the world. Methods We use a phenomenological model to ascertain the temporal patterns and transmission potential of ZIKV in various countries/territories, by fitting the model to Zika case data from Yap Island and French Polynesia in the Oceania region and 11 countries/territories with confirmed case data, namely, Colombia, Ecuador, French Guiana, Guadeloupe, Guatemala, Mexico, Nicaragua, Panama, Puerto Rico, Saint Martin, and Suriname, to pinpoint the waves of infections in each country/territory and to estimate the respective basic reproduction number R0. Results Six of these time series datasets resulted in statistically significant model fit of at least one wave of reported cases, namely that of French Polynesia, Colombia, Puerto Rico, Guatemala, Suriname and Saint Martin. However, only Colombia and Guatemala exhibited two waves of cases while the others had only one wave. Temporal patterns of the second wave in Colombia and the single wave in Suriname are very similar, with the respective turning points separated by merely a week. Moreover, the mean estimates of R0 for Colombia, Guatemala and Suriname, all land-based populations, range between 1.05 and 1.75, while the corresponding mean estimates for R0 of island populations in French Polynesia, Puerto Rico and Saint Martin are significantly lower with a range of 5.70–6.89. We also fit the Richards model to Zika case data from six main archipelagos in French

  16. Building America Case Study: Multifamily Central Heat Pump Water Heaters, Davis, California

    M. Hoeschele, E. Weitzel

    2017-03-01

    Although heat pump water heaters (HPWHs) have gained significant attention in recent years as a high efficiency electric water heating solution for single family homes, central HPWHs for commercial or multi-family applications are not as well documented in terms of measured performance and cost effectiveness. To evaluate this technology, the Alliance for Residential Building Innovation team monitored the performance of a 10.5 ton central HPWH installed on a student apartment building at the West Village Zero Net Energy Community in Davis, California. Monitoring data collected over a 16-month period were then used to validate a TRNSYS simulation model. The TRNSYS model was then used to project performance in different climates using local electric rates. Results of the study indicate that after some initial commissioning issues, the HPWH operated reliably with an annual average efficiency of 2.12 (Coefficient of Performance). The observed efficiency was lower than the unit's rated efficiency, primarily due to the fact that the system rarely operated under steady-state conditions. Changes in the system configuration, storage tank sizing, and control settings would likely improve the observed field efficiency. Modeling results suggest significant energy savings relative to electric storage water heating systems (typical annual efficiencies around 0.90) providing for typical simple paybacks of six to ten years without any incentives. The economics versus gas water heating are currently much more challenging given the current low natural gas prices in much of the country. Increased market size for this technology would benefit cost effectiveness and spur greater technology innovation.

  17. Building America Case Study: Multifamily Central Heat Pump Water Heaters, Davis, California

    2017-03-08

    Although heat pump water heaters (HPWHs) have gained significant attention in recent years as a high efficiency electric water heating solution for single family homes, central HPWHs for commercial or multi-family applications are not as well documented in terms of measured performance and cost effectiveness. To evaluate this technology, the Alliance for Residential Building Innovation team monitored the performance of a 10.5 ton central HPWH installed on a student apartment building at the West Village Zero Net Energy Community in Davis, California. Monitoring data collected over a 16-month period were then used to validate a TRNSYS simulation model. The TRNSYS model was then used to project performance in different climates using local electric rates. Results of the study indicate that after some initial commissioning issues, the HPWH operated reliably with an annual average efficiency of 2.12 (Coefficient of Performance). The observed efficiency was lower than the unit's rated efficiency, primarily due to the fact that the system rarely operated under steady-state conditions. Changes in the system configuration, storage tank sizing, and control settings would likely improve the observed field efficiency. Modeling results suggest significant energy savings relative to electric storage water heating systems (typical annual efficiencies around 0.90) providing for typical simple paybacks of six to ten years without any incentives. The economics versus gas water heating are currently much more challenging given the current low natural gas prices in much of the country. Increased market size for this technology would benefit cost effectiveness and spur greater technology innovation.

  18. Genetic characterization of local Criollo pig breeds from the Americas using microsatellite markers.

    Revidatti, M A; Delgado Bermejo, J V; Gama, L T; Landi Periati, V; Ginja, C; Alvarez, L A; Vega-Pla, J L; Martínez, A M

    2014-11-01

    Little is known about local Criollo pig genetic resources and relationships among the various populations. In this paper, genetic diversity and relationships among 17 Criollo pig populations from 11 American countries were assessed with 24 microsatellite markers. Heterozygosities, F-statistics, and genetic distances were estimated, and multivariate, genetic structure and admixture analyses were performed. The overall means for genetic variability parameters based on the 24 microsatellite markers were the following: mean number of alleles per locus of 6.25 ± 2.3; effective number of alleles per locus of 3.33 ± 1.56; allelic richness per locus of 4.61 ± 1.37; expected and observed heterozygosity of 0.62 ± 0.04 and 0.57 ± 0.02, respectively; within-population inbreeding coefficient of 0.089; and proportion of genetic variability accounted for by differences among breeds of 0.11 ± 0.01. Genetic differences were not significantly associated with the geographical location to which breeds were assigned or their country of origin. Still, the NeighborNet dendrogram depicted the clustering by geographic origin of several South American breeds (Criollo Boliviano, Criollo of northeastern Argentina wet, and Criollo of northeastern Argentina dry), but some unexpected results were also observed, such as the grouping of breeds from countries as distant as El Salvador, Mexico, Ecuador, and Cuba. The results of genetic structure and admixture analyses indicated that the most likely number of ancestral populations was 11, and most breeds clustered separately when this was the number of predefined populations, with the exception of some closely related breeds that shared the same cluster and others that were admixed. These results indicate that Criollo pigs represent important reservoirs of pig genetic diversity useful for local development as well as for the pig industry.

  19. Anxiety and depression during pregnancy in Central America : a cross-sectional study among pregnant women in the developing country Nicaragua

    Verbeek, T.; Arjadi, R.; Vendrik, J. J.; Burger, H.; Berger, M. Y.

    2015-01-01

    Background: Around the world, maternal psychopathology during pregnancy is associated with a range of negative consequences for mother and child. Nevertheless, in Central America the magnitude of this public health problem is still unknown. The objective of this first explorative study was to

  20. Health care providers and human trafficking: What do they know, what do they need to know? Findings from the middle East, the Caribbean, and Central America

    Viergever, R.F.; West, H.; Borland, R.; Zimmerman, C.

    2015-01-01

    BACKGROUND: Human trafficking is a crime that commonly results in acute and chronic physical and psychological harm. To foster more informed health sector responses to human trafficking, training sessions for health care providers were developed and pilot-tested in the Middle East, Central America,

  1. Estimativas de possiveis recursos de petroleo e gas na America Central e na America do Sul [Estimates of possible petroleum and gas resources in Central American and South America

    Schenk, C.S.

    2001-01-01

    O U.S. Geological Survey recentemente completou estimativas de possíveis recursos de petróleo e gás em 130 áreas petrolíferas pré-determinadas no mundo (USGS, 2000). Vinte e três destas áreas ficam na América do Sul, na América Central, e no Caribe (fig. 1). Os resultados estão apresentados na tabela 1. Nas 23 áreas, estimamos um total de 105 BBO e um total de 487 TCFG. A região composta de América Central mais América do Sul ficou em terceiro lugar no mundo em termos de possíveis recursos de petróleo e gás. No primeiro lugar ficou o Oriente Médio e no segundo lugar ficou a antiga União Soviética (USGS, 2000). As áreas com maiores probabilidades de encontrar depósitos gigantes de petróleo e gás se localizam nas áreas do Oceano Atlântico começando com a Bacia de Santos no sul até a Bacia Guyana-Suriname no norte. As possibilidades de existirem depósitos gigantes são maiores nas áreas submersas do mar até profundidades de 3,600 m. Diversos depósitos gigantes de petróleo foram descobertos no mar na Bacia de Campos e ainda podem serem encontrados depósitos similares na Bacia de Campos e suas imediações.

  2. Population genetics of the endangered Crowned Solitary Eagle (Buteogallus coronatus) in South America

    Canal, David; Roques, Séverine; Negro, Juan J.; Sarasola, José Hernán

    2017-01-01

    The Crowned Solitary Eagle (Buteogallus coronatus) is one of the rarest and most severely threatened birds of prey in the Neotropical region. We studied levels of neutral genetic diversity, population structure, and the demographic history of the species using 55 contemporary samples covering a large fraction of the species range, which were genotyped at 17 microsatellite loci. Our results indicated genetic homogeneity across the sampled regions, which may be explained by a high dispersal cap...

  3. Successes, challenges and needs regarding rural health medical education in continental Central America: a literature review and narrative synthesis.

    Colon-Gonzalez, Maria C; El Rayess, Fadya; Guevara, Sara; Anandarajah, Gowri

    2015-01-01

    Central American countries, like many others, face a shortage of rural health physicians. Most medical schools in this region are located in urban areas and focus on tertiary care training rather than on community health or primary care, which are better suited for rural practice. However, many countries require young physicians to do community service in rural communities to address healthcare provider shortages. This study aimed to: (a) synthesize what is known about the current state of medical education preparing physicians for rural practice in this region, and (b) identify common needs, challenges and opportunities for improving medical education in this area. A comprehensive literature review was conducted between December 2013 and May 2014. The stepwise, reproducible search process included English and Spanish language resources from both data-based web search engines (PubMed, Web of Science/Web of Knowledge, ERIC and Google Scholar) and the grey literature. Search criteria included MeSH terms: 'medical education', 'rural health', 'primary care', 'community medicine', 'social service', in conjunction with 'Central America', 'Latin America', 'Mexico', 'Guatemala', 'Belize', 'El Salvador', 'Nicaragua', 'Honduras', 'Costa Rica' and 'Panama'. Articles were included in the review if they (1) were published after 1984; (2) focused on medical education for rural health, primary care, community health; and (3) involved the countries of interest. A narrative synthesis of the content of resources meeting inclusion criteria was done using qualitative research methods to identify common themes pertaining to the study goals. The search revealed 20 resources that met inclusion criteria. Only four of the 20 were research articles; therefore, information about this subject was primarily derived from expert opinion. Thematic analysis revealed the historical existence of several innovative programs that directly address rural medicine training needs, suggesting that

  4. Coral zonation and diagenesis of an emergent Pleistocene patch reef, Belize, Central America

    Lighty, R.G.; Russell, K.L.

    1985-01-01

    Transect mapping and petrologic studies reveal a new depositional model and limited diagenesis of a well-exposed Pleistocene reef outcrop at Ambergris Cay, northern Belize. This emergent shelf-edge reef forms a rocky wave-washed headland at the northern terminus of the present-day 250 km long flourishing Belize Barrier Reef. Previously, the Belize reef outcrop was thought to extend southward in the subsurface beneath the modern barrier reef as a Pleistocene equivalent. The authors study indicate that this outcrop is a large, coral patch reef and not part of a barrier reef trend. Sixteen transects 12.5 m apart described in continuous cm increments from fore reef to back reef identified: extensive deposits of broken Acropora cervicornis; small thickets of A. palmata with small, oriented branches; and muddy skeletal sediments with few corals or reef rubble. Thin section and SEM studies show three phases of early submarine cementation: syntaxial and rosette aragonite; Mg-calcite rim cement and peloids; and colloidal Mg-calcite geopetal fill. Subaerial exposure in semi-arid northern Belize caused only minor skeletal dissolution, some precipitation of vadose whisker calcite, and no meteoric phreatic diagenesis. Facies geometry, coral assemblages, lack of rubble deposits, coralline algal encrustations and Millepora framework, and recognition of common but discrete submarine cements, all indicate that this Pleistocene reef was an isolated, coral-fringed sediment buildup similar to may large patch reefs existing today in moderate-energy shelf environments behind the modern barrier reef in central and southern Belize.

  5. Geology of the Pavana geothermal area, Departamento de Choluteca, Honduras, Central America: Field report

    Eppler, D.B.; Heiken, G.; Wohletz, K.; Flores, W.; Paredes, J.R.; Duffield, W.A.

    1987-09-01

    The Pavana geothermal area is located in southern Honduras near the Gulf of Fonseca. This region is underlain by late Tertiary volcanic rocks. Within ranges near the geothermal manifestations, the rock sequences is characterized by intermediate to mafic laharic breccias and lavas overlain by silicic tuffs and lavas, which are in turn overlain by intermediate to mafic breccias, lavas, and tuffs. The nearest Quaternary volcanoes are about 40 km to the southwest, where the chain of active Central American volcanoes crosses the mouth of the Gulf of Fonseca. Structure of the Pavana area is dominated by generally northwest-trending, southwest-dipping normal faults. This structure is topographically expressed as northwest-trending escarpments that bound blocks of bedrock separated by asymmetric valleys that contain thin alluvial deposits. Thermal waters apparently issue from normal faults and are interpreted as having been heated during deep circulation along fault zones within a regional environment of elevated heat flow. Natural outflow from the main thermal area is about 3000 l/min of 60/sup 0/C water. Geothermometry of the thermal waters suggests a reservoir base temperature of about 150/sup 0/C.

  6. Genetic diversity and host specificity varies across three genera of blood parasites in ducks of the Pacific Americas Flyway

    Reeves, Andrew B.; Smith, Matthew M.; Meixell, Brandt W.; Fleskes, Joseph P.; Ramey, Andrew M.

    2015-01-01

    Birds of the order Anseriformes, commonly referred to as waterfowl, are frequently infected by Haemosporidia of the genera Haemoproteus, Plasmodium, and Leucocytozoon via dipteran vectors. We analyzed nucleotide sequences of the Cytochrome b (Cytb) gene from parasites of these genera detected in six species of ducks from Alaska and California, USA to characterize the genetic diversity of Haemosporidia infecting waterfowl at two ends of the Pacific Americas Flyway. In addition, parasite Cytb sequences were compared to those available on a public database to investigate specificity of genetic lineages to hosts of the order Anseriformes. Haplotype and nucleotide diversity of Haemoproteus Cytb sequences was lower than was detected for Plasmodium and Leucocytozoon parasites. Although waterfowl are presumed to be infected by only a single species of Leucocytozoon, L. simondi, diversity indices were highest for haplotypes from this genus and sequences formed five distinct clades separated by genetic distances of 4.9%–7.6%, suggesting potential cryptic speciation. All Haemoproteus andLeucocytozoon haplotypes derived from waterfowl samples formed monophyletic clades in phylogenetic analyses and were unique to the order Anseriformes with few exceptions. In contrast, waterfowl-origin Plasmodium haplotypes were identical or closely related to lineages found in other avian orders. Our results suggest a more generalist strategy for Plasmodiumparasites infecting North American waterfowl as compared to those of the generaHaemoproteus and Leucocytozoon.

  7. Genetic diversity, endemism and phylogeny of lampreys within the genus Lampetra sensu stricto (Petromyzontiformes: Petromyzontidae) in western North America.

    Boguski, D A; Reid, S B; Goodman, D H; Docker, M F

    2012-11-01

    Phylogenetic structure of four Lampetra species from the Pacific drainage of North America (western brook lamprey Lampetra richardsoni, Pacific brook lamprey Lampetra pacifica, river lamprey Lampetra ayresii and Kern brook lamprey Lampetra hubbsi) and unidentified Lampetra specimens (referred to as Lampetra sp.) from 36 locations was estimated using the mitochondrial cytochrome b gene. Maximum parsimony and Bayesian inferences did not correspond with any taxonomic scheme proposed to date. Rather, although L. richardsoni (from Alaska to California) and L. ayresii (from British Columbia to California) together constituted a well-supported clade distinct from several genetically divergent Lampetra populations in Oregon and California, these two species were not reciprocally monophyletic. The genetically divergent populations included L. pacifica (from the Columbia River basin) and L. hubbsi (from the Kern River basin) and four Lampetra sp. populations in Oregon (Siuslaw River and Fourmile Creek) and California (Kelsey and Mark West Creeks). These four Lampetra sp. populations showed genetic divergence between 2.3 and 5.7% from any known species (and up to 8.0% from each other), and may represent morphologically cryptic and thus previously undescribed species. A fifth population (from Paynes Creek, California) may represent a range extension of L. hubbsi into the Upper Sacramento River. © 2012 The Authors. Journal of Fish Biology © 2012 The Fisheries Society of the British Isles.

  8. Genetic structure of the tiger mosquito, Aedes albopictus, in Cameroon (Central Africa.

    Basile Kamgang

    Full Text Available Aedes albopictus (Skuse, 1884 (Diptera: Culicidae, a mosquito native to Asia, has recently invaded all five continents. In Central Africa it was first reported in the early 2000s, and has since been implicated in the emergence of arboviruses such as dengue and chikungunya in this region. Recent genetic studies of invasive species have shown that multiple introductions are a key factor for successful expansion in new areas. As a result, phenotypic characters such as vector competence and insecticide susceptibility may vary within invasive pest species, potentially affecting vector efficiency and pest management. Here we assessed the genetic variability and population genetics of Ae. albopictus isolates in Cameroon (Central Africa, thereby deducing their likely geographic origin.Mosquitoes were sampled in 2007 in 12 localities in southern Cameroon and analyzed for polymorphism at six microsatellite loci and in two mitochondrial DNA regions (ND5 and COI. All the microsatellite markers were successfully amplified and were polymorphic, showing moderate genetic structureamong geographic populations (F(ST  = 0.068, P < 0.0001. Analysis of mtDNA sequences revealed four haplotypes each for the COI and ND5 genes, with a dominant haplotype shared by all Cameroonian samples. The weak genetic variation estimated from the mtDNA genes is consistent with the recent arrival of Ae. albopictus in Cameroon. Phylogeographic analysis based on COI polymorphism indicated that Ae. albopictus populations from Cameroon are related to tropical rather than temperate or subtropical outgroups.The moderate genetic diversity observed among Cameroonian Ae. albopictus isolates is in keeping with recent introduction and spread in this country. The genetic structure of natural populations points to multiple introductions from tropical regions.

  9. 300 years of hydrological records and societal responses to droughts and floods on the Pacific coast of Central America

    Guevara-Murua, Alvaro; Williams, Caroline A.; Hendy, Erica J.; Imbach, Pablo

    2018-02-01

    The management of hydrological extremes and impacts on society is inadequately understood because of the combination of short-term hydrological records, an equally short-term assessment of societal responses and the complex multi-directional relationships between the two over longer timescales. Rainfall seasonality and inter-annual variability on the Pacific coast of Central America is high due to the passage of the Inter Tropical Convergence Zone (ITCZ) and the El Niño-Southern Oscillation (ENSO). Here we reconstruct hydrological variability and demonstrate the potential for assessing societal impacts by drawing on documentary sources from the cities of Santiago de Guatemala (now Antigua Guatemala) and Guatemala de la Asunción (now Guatemala City) over the period from 1640 to 1945. City and municipal council meetings provide a rich source of information dating back to the beginning of Spanish colonisation in the 16th century. We use almost continuous sources from 1640 AD onwards, including > 190 volumes of Actas de Cabildo and Actas Municipales (minutes of meetings of the city and municipal councils) held by the Archivo Histórico de la Municipalidad de Antigua Guatemala (AHMAG) and the Archivo General de Centro América (AGCA) in Guatemala City. For this 305-year period (with the exception of a total of 11 years during which the books were either missing or damaged), information relating to Catholic rogation ceremonies and reports of flooding events and crop shortages were used to classify the annual rainy season (May to October) on a five-point scale from very wet to very dry. In total, 12 years of very wet conditions, 25 years of wetter than usual conditions, 34 years of drier conditions and 21 years of very dry conditions were recorded. An extended drier period from the 1640s to the 1740s was identified and two shorter periods (the 1820s and the 1840s) were dominated by dry conditions. Wetter conditions dominated the 1760s-1810s and possibly record more

  10. Assessment of contemporary genetic diversity and inter-taxa/inter-region exchange of avian paramyxovirus serotype 1 in wild birds sampled in North America

    Ramey, Andy M.; Goraichuk, Iryna V.; Hicks, Joseph T.; Dimitrov, Kiril M.; Poulson, Rebecca L.; Stallknecht, David E.; Bahl, Justin; Afonso, Claudio L.

    2017-01-01

    BackgroundAvian paramyxovirus serotype 1 (APMV-1) viruses are globally distributed, infect wild, peridomestic, and domestic birds, and sometimes lead to outbreaks of disease. Thus, the maintenance, evolution, and spread of APMV-1 viruses are relevant to avian health.MethodsIn this study we sequenced the fusion gene from 58 APMV-1 isolates recovered from thirteen species of wild birds sampled throughout the USA during 2007–2014. We analyzed sequence information with previously reported data in order to assess contemporary genetic diversity and inter-taxa/inter-region exchange of APMV-1 in wild birds sampled in North America.ResultsOur results suggest that wild birds maintain previously undescribed genetic diversity of APMV-1; however, such diversity is unlikely to be pathogenic to domestic poultry. Phylogenetic analyses revealed that APMV-1 diversity detected in wild birds of North America has been found in birds belonging to numerous taxonomic host orders and within hosts inhabiting multiple geographic regions suggesting some level of viral exchange. However, our results also provide statistical support for associations between phylogenetic tree topology and host taxonomic order/region of sample origin which supports restricted exchange among taxa and geographical regions of North America for some APMV-1 sub-genotypes.ConclusionsWe identify previously unrecognized genetic diversity of APMV-1 in wild birds in North America which is likely a function of continued viral evolution in reservoir hosts. We did not, however, find support for the emergence or maintenance of APMV-1 strains predicted to be pathogenic to poultry in wild birds of North America outside of the order Suliformes (i.e., cormorants). Furthermore, genetic evidence suggests that ecological drivers or other mechanisms may restrict viral exchange among taxa and regions of North America. Additional and more systematic sampling for APMV-1 in North America would likely provide further inference on viral

  11. Genetic diversity and phylogeography of highly zoonotic Echinococcus granulosus genotype G1 in the Americas (Argentina, Brazil, Chile and Mexico) based on 8279bp of mtDNA.

    Laurimäe, Teivi; Kinkar, Liina; Andresiuk, Vanessa; Haag, Karen Luisa; Ponce-Gordo, Francisco; Acosta-Jamett, Gerardo; Garate, Teresa; Gonzàlez, Luis Miguel; Saarma, Urmas

    2016-11-01

    Echinococcus granulosus is a taeniid cestode and the etiological agent of an infectious zoonotic disease known as cystic echinococcosis (CE) or hydatid disease. CE is a serious public health concern in many parts of the world, including the Americas, where it is highly endemic in many regions. Echinococcus granulosus displays high intraspecific genetic variability and is divided into multiple genotypes (G1-G8, G10) with differences in their biology and etiology. Of these, genotype G1 is responsible for the majority of human and livestock infections and has the broadest host spectrum. However, despite the high significance to the public and livestock health, the data on genetic variability and regional genetic differences of genotype G1 in America are scarce. The aim of this study was to evaluate the genetic variability and phylogeography of G1 in several countries in America by sequencing a large portion of the mitochondrial genome. We analysed 8279bp of mtDNA for 52 E. granulosus G1 samples from sheep, cattle and pigs collected in Argentina, Brazil, Chile and Mexico, covering majority of countries in the Americas where G1 has been reported. The phylogenetic network revealed 29 haplotypes and a high haplotype diversity (Hd=0.903). The absence of phylogeographic segregation between different regions in America suggests the importance of animal transportation in shaping the genetic structure of E. granulosus G1. In addition, our study revealed many highly divergent haplotypes, indicating a long and complex evolutionary history of E. granulosus G1 in the Americas. Copyright © 2016 Elsevier B.V. All rights reserved.

  12. Fungus Causing White-Nose Syndrome in Bats Accumulates Genetic Variability in North America with No Sign of Recombination.

    Trivedi, Jigar; Lachapelle, Josianne; Vanderwolf, Karen J; Misra, Vikram; Willis, Craig K R; Ratcliffe, John M; Ness, Rob W; Anderson, James B; Kohn, Linda M

    2017-01-01

    Emerging fungal diseases of wildlife are on the rise worldwide, and the white-nose syndrome (WNS) epidemic in North American bats is a catastrophic example. The causal agent of WNS is a single clone of the fungus Pseudogymnoascus destructans . Early evolutionary change in this clonal population has major implications for disease ecology and conservation. Accumulation of variation in the fungus through mutation, and shuffling of variation through recombination, could affect the virulence and transmissibility of the fungus and the durability of what appears to be resistance arising in some bat populations. Our genome-wide analysis shows that the clonal population of P. destructans has expanded in size from a single genotype, has begun to accumulate variation through mutation, and presents no evidence as yet of genetic exchange among individuals. IMPORTANCE Since its discovery in 2006, the emerging infectious disease known as white-nose syndrome has killed millions of bats in North America, making it one of the most devastating wildlife epidemics in recorded history. We demonstrate that there has been as yet only spontaneous mutation across the North American population of P. destructans , and we find no indication of recombination. Thus, selective forces, which might otherwise impact pathogenic virulence, have so far had essentially no genetic variation on which to act. Our study confirmed the time of origin for the first and, thus far, only introduction of P. destructans to North America. This system provides an unprecedented opportunity to follow the evolution of a host-pathogen interaction unfolding in real time.

  13. Cenozoic biogeography and evolution in direct-developing frogs of Central America (Leptodactylidae: Eleutherodactylus) as inferred from a phylogenetic analysis of nuclear and mitochondrial genes.

    Crawford, Andrew J; Smith, Eric N

    2005-06-01

    We report the first phylogenetic analysis of DNA sequence data for the Central American component of the genus Eleutherodactylus (Anura: Leptodactylidae: Eleutherodactylinae), one of the most ubiquitous, diverse, and abundant components of the Neotropical amphibian fauna. We obtained DNA sequence data from 55 specimens representing 45 species. Sampling was focused on Central America, but also included Bolivia, Brazil, Jamaica, and the USA. We sequenced 1460 contiguous base pairs (bp) of the mitochondrial genome containing ND2 and five neighboring tRNA genes, plus 1300 bp of the c-myc nuclear gene. The resulting phylogenetic inferences were broadly concordant between data sets and among analytical methods. The subgenus Craugastor is monophyletic and its initial radiation was potentially rapid and adaptive. Within Craugastor, the earliest splits separate three northern Central American species groups, milesi, augusti, and alfredi, from a clade comprising the rest of Craugastor. Within the latter clade, the rhodopis group as formerly recognized comprises three deeply divergent clades that do not form a monophyletic group; we therefore restrict the content of the rhodopis group to one of two northern clades, and use new names for the other northern (mexicanus group) and one southern clade (bransfordii group). The new rhodopis and bransfordii groups together form the sister taxon to a clade comprising the biporcatus, fitzingeri, mexicanus, and rugulosus groups. We used a Bayesian MCMC approach together with geological and biogeographic assumptions to estimate divergence times from the combined DNA sequence data. Our results corroborated three independent dispersal events for the origins of Central American Eleutherodactylus: (1) an ancestor of Craugastor entered northern Central America from South American in the early Paleocene, (2) an ancestor of the subgenus Syrrhophus entered northern Central America from the Caribbean at the end of the Eocene, and (3) a wave of

  14. Herbarium specimens reveal the footprint of climate change on flowering trends across north-central North America.

    Calinger, Kellen M; Queenborough, Simon; Curtis, Peter S

    2013-08-01

    Shifting flowering phenology with rising temperatures is occurring worldwide, but the rarity of co-occurring long-term observational and temperature records has hindered the evaluation of phenological responsiveness in many species and across large spatial scales. We used herbarium specimens combined with historic temperature data to examine the impact of climate change on flowering trends in 141 species collected across 116,000 km(2) in north-central North America. On average, date of maximum flowering advanced 2.4 days °C(-1), although species-specific responses varied from - 13.5 to + 7.3 days °C(-1). Plant functional types exhibited distinct patterns of phenological responsiveness with significant differences between native and introduced species, among flowering seasons, and between wind- and biotically pollinated species. This study is the first to assess large-scale patterns of phenological responsiveness with broad species representation and is an important step towards understanding current and future impacts of climate change on species performance and biodiversity. © 2013 The Authors. Ecology Letters published by John Wiley & Sons Ltd and CNRS.

  15. The performance of RegCM4 over the Central America and Caribbean region using different cumulus parameterizations

    Martínez-Castro, Daniel; Vichot-Llano, Alejandro; Bezanilla-Morlot, Arnoldo; Centella-Artola, Abel; Campbell, Jayaka; Giorgi, Filippo; Viloria-Holguin, Cecilia C.

    2018-06-01

    A sensitivity study of the performance of the RegCM4 regional climate model driven by the ERA Interim reanalysis is conducted for the Central America and Caribbean region. A set of numerical experiments are completed using four configurations of the model, with a horizontal grid spacing of 25 km for a period of 6 years (1998-2003), using three of the convective parameterization schemes implemented in the model, the Emanuel scheme, the Grell over land-Emanuel over ocean scheme and two configurations of the Tiedtke scheme. The objective of the study is to investigate the ability of each configuration to reproduce different characteristics of the temperature, circulation and precipitation fields for the dry and rainy seasons. All schemes simulate the general temperature and precipitation patterns over land reasonably well, with relatively high correlations compared to observation datasets, though in specific regions there are positive or negative biases, greater in the rainy season. We also focus on some circulation features relevant for the region, such as the Caribbean low level jet and sea breeze circulations over islands, which are simulated by the model with varied performance across the different configurations. We find that no model configuration assessed is best performing for all the analysis criteria selected, but the Tiedtke configurations, which include the capability of tuning in particular the exchanges between cloud and environment air, provide the most balanced range of biases across variables, with no outstanding systematic bias emerging.

  16. Five cases of acute Zika virus infection in French women of reproductive age returning from Central and South America.

    Penot, P; Balavoine, S; Leplatois, A; Brichler, S; Leparc-Goffart, I; Alloui, A-C; Flusin, O; Guilleminot, J; Amellou, M; Molina, J-M

    2017-08-01

    The favorable season for Aedes albopictus circulation has started in Europe and may lead to autochthonous transmission of Zika virus. Health care providers should be familiar with evocative clinical presentations and able to give updated information to women of reproductive age infected by Zika virus. We report five laboratory-confirmed Zika virus infections imported to metropolitan France from Central and South America between January and April, 2016. The five young women were not connected and not pregnant; common presentation combined a rash with persistent arthralgia. Zika virus was identified by RT-PCR from serum or urines, between two and eight days after the onset of the symptoms. As the duration of potential materno-foetal infectivity is still unknown, we were unable to answer with certitude to the patients' questions about the time interval to respect before attempting a pregnancy: one of them became pregnant one month after the diagnosis. Copyright © 2016 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier SAS. All rights reserved.

  17. Invasion of the Indo-Pacific blenny Omobranchus punctatus (Perciformes: Blenniidae on the Atlantic Coast of Central and South America

    Oscar Lasso-Alcalá

    Full Text Available We examined 308 specimens of the Indo-Pacific blenniid Omobranchus punctatus deposited in four museum collections, and analyzed data on their collection locations to assess its invasion on the Atlantic coast of Central and South America. This species occurs in shoreline estuarine and marine habitats in the Indo-West Pacific. Previous sampling and recent records in the Tropical West Atlantic from 1930 to 2004 produced 20 records for: Panamá, Colombia, Venezuela, Trinidad and Brazil. In this work, we provide data on 17 new records for the Gulfs of Venezuela and Paria in Venezuela, as well as four records for Maranhão and Pará states in NE Brazil. The temporal pattern of collections (1930 - 2009 and the proximity of most localities to ports and zones of ship traffic indicate that O. punctatus was initially introduced to the Atlantic by ships travelling from India to Trinidad. Within Brazil the introduction is linked to shipping connected to petroleum platforms. In Maranhão and Pará the introduction may have occurred as a result of fish sheltering in fouling on hulls of ships moving between ports around the mouth of the Amazon River. Alternatively, the spread of this species along of the American coast may reflect the expansion of the range of O. puntactus through larval dispersal in northward flowing currents. We recommend monitoring of this introduced species, and studies of its ecology in West Atlantic areas.

  18. Paleomagnetism of the Santa Fé Group, central Brazil: Implications for the late Paleozoic apparent polar wander path for South America

    Brandt, Daniele; Ernesto, Marcia; Rocha-Campos, Antonio Carlos; Dos Santos, Paulo Roberto

    2009-02-01

    Paleomagnetic and rockmagnetic data are reported for the Floresta Formation (Santa Fé Group) of the Sanfranciscana Basin, central Brazil. This formation represents the Permo-Carboniferous glacial record of the basin and comprises the Brocotó (diamictites and flow diamictites), Brejo do Arroz (red sandstones and shales with dropstones and invertebrate trails), and Lavado (red sandstones) members, which crop out near the cities of Santa Fé de Minas and Canabrava, Minas Gerais State. Both Brejo do Arroz and Lavado members were sampled in the vicinities of the two localities. Alternating field and thermal demagnetizations of 268 samples from 76 sites revealed reversed components of magnetization in all samples in accordance with the Permo-Carboniferous Reversed Superchron. The magnetic carriers are magnetite and hematite with both minerals exhibiting the same magnetization component, suggesting a primary origin for the remanence. We use the high-quality paleomagnetic pole for the Santa Fé Group (330.9°E 65.7°S; N = 60; α95 = 4.1°; k = 21) in a revised late Carboniferous to early Triassic apparent polar wander path for South America. On the basis of this result it is shown that an early Permian Pangea A-type fit is possible if better determined paleomagnetic poles become available.

  19. Population genetic structure of Bromus tectorum in the mountains of western North America

    Spencer Arnesen; Craig E. Coleman; Susan E. Meyer

    2017-01-01

    PREMISE OF THE STUDY: Invasive species are often initially restricted to a narrow range and may then expand through any of multiple mechanisms including phenotypic plasticity, in situ evolution, or selection on traits preadapted for new habitats. Our study used population genetics to explore possible processes by which the highly selfing invasive annual grass Bromus...

  20. Non invasive methods for genetic analysis applied to ecological and behavioral studies in Latino-America

    Susana González

    2007-07-01

    Full Text Available Documenting the presence and abundance of the neotropical mammals is the first step for understanding their population ecology, behavior and genetic dynamics in designing conservation plans. The combination of field research with molecular genetics techniques are new tools that provide valuable biological information avoiding the disturbance in the ecosystems, trying to minimize the human impact in the process to gather biological information. The objective of this paper is to review the available non invasive sampling techniques that have been used in Neotropical mammal studies to apply to determine the presence and abundance, population structure, sex ratio, taxonomic diagnostic using mitochondrial markers, and assessing genetic variability using nuclear markers. There are a wide range of non invasive sampling techniques used to determine the species identification that inhabit an area such as searching for tracks, feces, and carcasses. Other useful equipment is the camera traps that can generate an image bank that can be valuable to assess species presence and abundance by morphology. With recent advances in molecular biology, it is now possible to use the trace amounts of DNA in feces and amplify it to analyze the species diversity in an area, and the genetic variability at intraspecific level. This is particularly helpful in cases of sympatric and cryptic species in which morphology failed to diagnose the taxonomic status of several species of brocket deer of the genus Mazama.

  1. Acceptance of a food of animal origin obtained through genetic modification and cloning in South America

    Schnettler, Berta; Velásquez, Carlos; Miranda, Horacio

    2015-01-01

    With the aim of comparing the acceptance of milk obtained from cloned, genetically modified (GM) and conventionally bred cows among working adults and university students, and identifying and characterizing typologies among both subsamples in terms of their preferences, a survey was applied to 40...

  2. Phenotypic and genotypic heterogeneity among Streptococcus iniae isolates recovered from cultured and wild fish in North America, Central America and the Caribbean Islands

    Streptococcus iniae, the etiological agent of streptococcosis in fish, is an important pathogen of cultured and wild fish worldwide. During the last decade outbreaks of streptococcosis have occurred in a wide range of cultured and wild fish in the Americas and Caribbean islands. To gain a better und...

  3. Cold episodes in the Peruvian Central Andes: Composites, Types, and their Impacts over South America (1958-2014)

    Sulca, J. C.; Vuille, M. F.; Roundy, P. E.; Trasmonte, G.; Silva, Y.; Takahashi, K.

    2015-12-01

    The Mantaro basin (MB) is located in the central Peruvian Andes. Occasionally, cold episodes are observed during austral summer (January-March), that strongly damage crops. However, little is known about the causes and impacts of such cold episodes. The main goal of this study is thus to characterize cold episodes in the MB and assess their large-scale circulation and teleconnections over South America (SA) during austral summer. To identify cold events in the MB daily minimum temperature (Tmin) for the period 1958-2014 from Huayao station, located within the MB was used. A cold episode is defined when daily minimum temperature drops below its 10-percentile for at least one day. Additionally, to study the sensitivity between physical mechanisms associated with cold episodes and temperature, cold episodes are classified in three groups: Weak cold episodes (7.5 ≤ Tmin ≤ 10 percentile), strong cold episodes (Tmin ≤ 2.5 percentile), but excluding the 9 coldest events (Tmin ≤ 0 ͦ C), henceforth referred to as extraordinary cold episodes. Several gridded reanalysis were used to characterize the large-scale circulation, cloud cover and rainfall over SA associated with these events. Weak and strong cold episodes in the MB are mainly associated with a weakening of the Bolivian High-Nordeste Low system by tropical-extratropical interactions. Both types of cold episodes are associated with westerly wind anomalies at mid- and upper-tropospheric levels aloft the Peruvian Central Andes, which inhibit the influx of humid air masses from the lowlands to the east and hence limit the development of cloud cover (e.g., positive OLR anomalies over MB). The resulting clear sky conditions cause nighttime temperatures to drop, leading to cold extremes below 10-percentile. Simultaneously, northeastern Brazil (NEB) registers negative OLR anomalies, strong convection and enhanced cloud cover because displacement of the South Atlantic Convergence Zone (SACZ) toward the northeast of

  4. In the heartland of Eurasia: the multilocus genetic landscape of Central Asian populations

    Martínez-Cruz, Begoña; Vitalis, Renaud; Ségurel, Laure; Austerlitz, Frédéric; Georges, Myriam; Théry, Sylvain; Quintana-Murci, Lluis; Hegay, Tatyana; Aldashev, Almaz; Nasyrova, Firuza; Heyer, Evelyne

    2011-01-01

    Located in the Eurasian heartland, Central Asia has played a major role in both the early spread of modern humans out of Africa and the more recent settlements of differentiated populations across Eurasia. A detailed knowledge of the peopling in this vast region would therefore greatly improve our understanding of range expansions, colonizations and recurrent migrations, including the impact of the historical expansion of eastern nomadic groups that occurred in Central Asia. However, despite its presumable importance, little is known about the level and the distribution of genetic variation in this region. We genotyped 26 Indo-Iranian- and Turkic-speaking populations, belonging to six different ethnic groups, at 27 autosomal microsatellite loci. The analysis of genetic variation reveals that Central Asian diversity is mainly shaped by linguistic affiliation, with Turkic-speaking populations forming a cluster more closely related to East-Asian populations and Indo-Iranian speakers forming a cluster closer to Western Eurasians. The scattered position of Uzbeks across Turkic- and Indo-Iranian-speaking populations may reflect their origins from the union of different tribes. We propose that the complex genetic landscape of Central Asian populations results from the movements of eastern, Turkic-speaking groups during historical times, into a long-lasting group of settled populations, which may be represented nowadays by Tajiks and Turkmen. Contrary to what is generally thought, our results suggest that the recurrent expansions of eastern nomadic groups did not result in the complete replacement of local populations, but rather into partial admixture. PMID:20823912

  5. Origin of silicic magmas along the Central American volcanic front: Genetic relationship to mafic melts

    Vogel, Thomas A.; Patino, Lina C.; Eaton, Jonathon K.; Valley, John W.; Rose, William I.; Alvarado, Guillermo E.; Viray, Ela L.

    2006-09-01

    Silicic pyroclastic flows and related deposits are abundant along the Central American volcanic front. These silicic magmas erupted through both the non-continental Chorotega block to the southeast and the Paleozoic continental Chortis block to the northwest. The along-arc variations of the silicic deposits with respect to diagnostic trace element ratios (Ba/La, U/Th, Ce/Pb), oxygen isotopes, Nd and Sr isotope ratios mimic the along-arc variation in the basaltic and andesitic lavas. This variation in the lavas has been interpreted to indicate relative contributions from the slab and asthenosphere to the basaltic magmas [Carr, M.J., Feigenson, M.D., Bennett, E.A., 1990. Incompatible element and isotopic evidence for tectonic control of source mixing and melt extraction along the Central American arc. Contributions to Mineralogy and Petrology, 105, 369-380.; Patino, L.C., Carr, M.J. and Feigenson, M.D., 2000. Local and regional variations in Central American arc lavas controlled by variations in subducted sediment input. Contributions to Mineralogy and Petrology, 138 (3), 265-283.]. With respect to along-arc trends in basaltic lavas the largest contribution of slab fluids is in Nicaragua and the smallest input from the slab is in central Costa Rica — similar trends are observed in the silicic pyroclastic deposits. Data from melting experiments of primitive basalts and basaltic andesites demonstrate that it is difficult to produce high K 2O/Na 2O silicic magmas by fractional crystallization or partial melting of low-K 2O/Na 2O sources. However fractional crystallization or partial melting of medium- to high-K basalts can produce these silicic magmas. We interpret that the high-silica magmas associated Central America volcanic front are partial melts of penecontemporaneous, mantle-derived, evolved magmas that have ponded and crystallized in the mid-crust — or are melts extracted from these nearly completely crystallized magmas.

  6. Genetic heterogeneity in supratentorial and infratentorial primitive neuroectodermal tumours of the central nervous system.

    Inda, M M; Perot, C; Guillaud-Bataille, M; Danglot, G; Rey, J A; Bello, M J; Fan, X; Eberhart, C; Zazpe, I; Portillo, E; Tuñón, T; Martínez-Peñuela, J M; Bernheim, A; Castresana, J S

    2005-12-01

    Medulloblastoma (MB), a kind of infratentorial primitive neuroectodermal tumour (PNET), is the most frequent malignant brain tumour in childhood. In contrast, supratentorial PNET (sPNET) are very infrequent tumours, but they are histologically similar to MB, although they present a worse clinical outcome. We investigated the differences in genetic abnormalities between sPNET and MB. We analysed 20 central PNET (14 MB and six sPNET) by conventional comparative genomic hybridization (CGH) in order to determine whether a different genetic profile for each tumour exists. Isochromosome 17q was detected in four of the 14 MB cases, but not in any sPNET. Gains at 17q and 7 happened more frequently in MB, and those at 1q in sPNET. Losses at chromosome 10 were detected only in MB, while losses at 16p and 19p happened more frequently in sPNET. A new amplification site, on 4q12, was detected in two MB. Central PNET are a heterogeneous group of tumours from the genetic point of view. The present and previous data, together with further results from larger series, might contribute to the establishment of specific treatments for supratentorial and infratentorial PNET.

  7. Genetic parameters for type classification of Nelore cattle on central performance tests at pasture in Brazil.

    Lima, Paulo Ricardo Martins; Paiva, Samuel Rezende; Cobuci, Jaime Araujo; Braccini Neto, José; Machado, Carlos Henrique Cavallari; McManus, Concepta

    2013-10-01

    The objective of this study was to characterize Nelore cattle on central performance tests in pasture, ranked by the visual classification method EPMURAS (structure, precocity, muscle, navel, breed, posture, and sexual characteristics), and to estimate genetic and phenotypic correlations between these parameters, including visual as well as production traits (initial and final weight on test, weight gain, and weight corrected for 550 days). The information used in the study was obtained on 21,032 Nelore bulls which were participants in the central performance test at pasture of the Brazilian Association for Zebu Breeders (ABCZ). Heritabilities obtained were from 0.19 to 0.50. Phenotypic correlations were positive from 0.70 to 0.97 between the weight traits, from 0.65 to 0.74 between visual characteristics, and from 0.29 to 0.47 between visual characteristics and weight traits. The genetic correlations were positive ranging from 0.80 to 0.98 between the characteristics of structure, precocity and musculature, from 0.13 to 0.64 between the growth characteristics, and from 0.41 to 0.97 between visual scores and weight gains. Heritability and genetic correlations indicate that the use of visual scores, along with the selection for growth characteristics, can bring positive results in selection of beef cattle for rearing on pasture.

  8. Addressing the Socioeconomic Impacts of Genetically Modified ...

    But despite rapid diffusion of genetically modified (GM) cotton - and ... Argentina, South America, Brazil, Paraguay, North and Central America, China, India, Pakistan ... A Expansão Da Cultura Do Algodão Transgênico Na Região Do Norte De ...

  9. Biofuels in Central America

    Sanders, E.

    2007-08-01

    This report presents the results of an analysis of the biofuel markets in El Salvador, Panama, Costa Rica and Honduras. The aim of this report is to provide insight in the current situation and the expected developments in these markets and thus to provide investors with an image of the opportunities that could be present in this sector. An attempt has been made to provide a clear overview of this sector in the countries concerned. Due to a lack of data this has not been fully accomplished in some cases. [mk] [nl

  10. Assessing and mapping drought hazard in Africa and South-Central America with a Meteorological Drought Severity Index

    Carrao, Hugo; Barbosa, Paulo; Vogt, Jürgen

    2015-04-01

    the intra-annual variability of precipitation in estimating the severity of events that can impact on seasonal activities. The MDSI is standardized in space and time, and considers the relative monthly precipitation deficits and the seasonal influence of precipitation regimes in the meteorological drought severity computation. In this study, the calculation of the MDSI is performed with monthly precipitation totals from the Full Data Reanalysis Monthly Product Version 6.0 of the Global Precipitation Climatology Centre (GPCC). This dataset provides a global analysis at 0.5 dd latitude/longitude grid spacing of monthly precipitation over land from operational in situ rain gauges collected between January 1901 and December 2010. Using the MDSI, we estimated the severity of drought events that occurred in the past 100 years in Africa and South-Central America, and produced drought hazard maps based on the probability of exceedance the median historical severity. Overall, results indicate that drought hazard is high for semiarid areas, such as Northeastern and Southern South America, as well as Eastern and Southwestern Africa. Since available water resources in semiarid areas are already insufficient to permanently meet the demands of human activities, the outcomes highlight the aggravated risk for food security and confirm the need for the implementation of disaster mitigation measures in those regions.

  11. [Breast feeding practice and activities for its promotion in Central America, Panamá and Dominican Republic].

    García, B; Delgado, H L; Valverde, V; Townsend, J; Fischer, M; Praun, A

    1985-06-01

    This paper summarizes the data presented by the representatives of Central America, Panama and the Dominican Republic at the II Regional Seminar on the Promotion of Breast-Feeding, held in Isla Contadora, Panama, April 25-29, 1983. The representatives of Costa Rica, Honduras and Panama provided up-to-date, representative data in regard to the breast-feeding practice. The average weaning age in the urban and rural areas of Costa Rica is 6 and 4 months, respectively. In Honduras and Panama, 43 and 17% of the infants from urban areas, and 21 and 37% of the babies from rural areas, respectively, were weaned before they reached four months of age. The need for availability of permanent systems to collect information on the breast-feeding practice in the different countries is pointed out. With regard to promotion actions, the absence of a national policy in favor of breast-feeding is evident. Moreover, in the national education systems, little importance is given to the subject. On the other hand, the advances achieved by some hospitals in favoring breast-feeding are mentioned. These include rooming in, the feeding of colostrum to newborns, and the establishment of human milk banks to feed premature babies whose mothers are unable to breast-feed them. Another acknowledged fact is that in the rural areas the agricultural home educators do not reinforce the breast-feeding practice. Also, there is a lack of information on the fulfillment of laws instituted for the protection of pregnant and lactating mothers, as far as pre and postnatal rest is concerned.

  12. LCE: leaf carbon exchange data set for tropical, temperate, and boreal species of North and Central America.

    Smith, Nicholas G; Dukes, Jeffrey S

    2017-11-01

    Leaf canopy carbon exchange processes, such as photosynthesis and respiration, are substantial components of the global carbon cycle. Climate models base their simulations of photosynthesis and respiration on an empirical understanding of the underlying biochemical processes, and the responses of those processes to environmental drivers. As such, data spanning large spatial scales are needed to evaluate and parameterize these models. Here, we present data on four important biochemical parameters defining leaf carbon exchange processes from 626 individuals of 98 species at 12 North and Central American sites spanning ~53° of latitude. The four parameters are the maximum rate of Rubisco carboxylation (V cmax ), the maximum rate of electron transport for the regeneration of Ribulose-1,5,-bisphosphate (J max ), the maximum rate of phosphoenolpyruvate carboxylase carboxylation (V pmax ), and leaf dark respiration (R d ). The raw net photosynthesis by intercellular CO 2 (A/C i ) data used to calculate V cmax , J max , and V pmax rates are also presented. Data were gathered on the same leaf of each individual (one leaf per individual), allowing for the examination of each parameter relative to others. Additionally, the data set contains a number of covariates for the plants measured. Covariate data include (1) leaf-level traits (leaf mass, leaf area, leaf nitrogen and carbon content, predawn leaf water potential), (2) plant-level traits (plant height for herbaceous individuals and diameter at breast height for trees), (3) soil moisture at the time of measurement, (4) air temperature from nearby weather stations for the day of measurement and each of the 90 d prior to measurement, and (5) climate data (growing season mean temperature, precipitation, photosynthetically active radiation, vapor pressure deficit, and aridity index). We hope that the data will be useful for obtaining greater understanding of the abiotic and biotic determinants of these important biochemical

  13. First record of the genus Ctenipocoris (Heteroptera: Naucoridae) in Central America, with a preliminary key to the American species and description of a new species.

    Herrera, Federico

    2013-10-31

    A new naucorid species, Ctenipocoris oscari Herrera NEW SPECIES, is herein described for Costa Rica. It is the first species to be described in Central America and the sixth American species. Comparative notes are provided to differentiate this species from the others. Type material is deposited at the Zoological Museum of the University of Costa Rica (MZUCR), San José, Costa Rica. A preliminary key to the American species of the genus is provided.

  14. Population genetic history of Aristeus antennatus (Crustacea: Decapoda in the Western and Central Mediterranean Sea.

    Annamaria Marra

    Full Text Available Aristeus antennatus is an ecologically and economically important deep-water species in the Mediterranean Sea. In this study we investigated the genetic variability of A. antennatus sampled from 10 sampling stations in the Western and Central Mediterranean. By comparing our new samples with available data from the Western area, we aim to identify potential genetic stocks of A. antennatus and to reconstruct its historical demography in the Mediterranean. We analyzed two regions of mitochondrial DNA in 319 individuals, namely COI and 16S. We found two main results: i the genetic diversity values consistent with previous data within the Mediterranean and the absence of barriers to gene flow within the Mediterranean Sea; ii a constant long-term effective population size in almost all demes but a strong signature of population expansion in the pooled sample about 50,000 years B.P./ago. We propose two explanation for our results. The first is based on the ecology of A. antennatus. We suggest the existence of a complex meta-population structured into two layers: a deeper-dwelling stock, not affected by fishing, which preserves the pattern of historical demography; and genetically homogeneous demes inhabiting the fishing grounds. The larval dispersal, adult migration and continuous movements of individuals from "virgin" deeper grounds not affected by fishing to upper fishing areas support an effective 'rescue effect' contributing to the recovery of the exploited stocks and explain their genetic homogeneity throughout the Mediterranean Sea. The second is based on the reproduction model of this shrimp: the high variance in offspring production calls for a careful interpretation of the data observed under classical population genetics and Kingman's coalescent. In both cases, management policies for A. antennatus will therefore require careful evaluation of the meta-population dynamics of all stocks in the Mediterranean. In the future, it will be

  15. Genetic diversity of Trichomonas vaginalis clinical isolates from Henan province in central China.

    Mao, Meng; Liu, Hui Li

    2015-07-01

    Trichomonas vaginalis is a flagellated protozoan parasite that infects the human urogenital tract, causing the most common non-viral, sexually transmitted disease worldwide. In this study, genetic variants of T. vaginalis were identified in Henan Province, China. Fragments of the small subunit of nuclear ribosomal RNA (18S rRNA) were amplified from 32 T. vaginalis isolates obtained from seven regions of Henan Province. Overall, 18 haplotypes were determined from the 18S rRNA sequences. Each sampled population and the total population displayed high haplotype diversity (Hd), accompanied by very low nucleotide diversity (Pi). In these molecular genetic variants, 91.58% genetic variation was derived from intra-regions. Phylogenetic analysis revealed no correlation between phylogeny and geographic distribution. Demographic analysis supported population expansion of T. vaginalis isolates from central China. Our findings showing moderate-to-high genetic variations in the 32 isolates of T. vaginalis provide useful knowledge for monitoring changes in parasite populations for the development of future control strategies.

  16. Data on medicinal plants used in Central America to manage diabetes and its sequelae (skin conditions, cardiovascular disease, kidney disease, urinary problems and vision loss

    Peter Giovannini

    2016-06-01

    Full Text Available The data described in this article is related to the review article “Medicinal plants used in the traditional management of diabetes and its sequelae in Central America: a review” (Giovannini et al., 2016 [1]. We searched publications on the useful plants of Central America in databases and journals by using selected relevant keywords. We then extracted reported uses of medicinal plants within the disease categories: diabetes mellitus, kidney disease, urinary problems, skin diseases and infections, cardiovascular disease, sexual dysfunction, vision loss, and nerve damage. The following countries were included in our definition of Central America: Belize, Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica and Panama. Data were compiled in a bespoke Access database. Plant names from the published sources were validated against The Plant List (TPL, (The Plant List, 2013 [2] and accepted names and synonyms were extracted. In total, the database includes 607 plant names obtained from the published sources which correspond to 537 plant taxa, 9271 synonyms and 1055 use reports.

  17. Discordant genetic diversity and geographic patterns between Crassicutis cichlasomae (Digenea: Apocreadiidae) and its cichlid host, "Cichlasoma" urophthalmus (Osteichthyes: Cichlidae), in Middle-America.

    Razo-Mendivil, Ulises; Vázquez-Domínguez, Ella; de León, Gerardo Pérez-Ponce

    2013-12-01

    Genetic analyses of hosts and their parasites are key to understand the evolutionary patterns and processes that have shaped host-parasite associations. We evaluated the genetic structure of the digenean Crassicutis cichlasomae and its most common host, the Mayan cichlid "Cichlasoma" urophthalmus, encompassing most of their geographical range in Middle-America (river basins in southeastern Mexico, Belize, and Guatemala together with the Yucatan Peninsula). Genetic diversity and structure analyses were done based on 167 cytochrome c oxidase subunit 1 sequences (330 bp) for C. cichlasomae from 21 populations and 161 cytochrome b sequences (599 bp) for "C." urophthalmus from 26 populations. Analyses performed included phylogenetic tree estimation under Bayesian inference and maximum likelihood analysis, genetic diversity, distance and structure estimates, haplotype networks, and demographic evaluations. Crassicutis cichlasomae showed high genetic diversity values and genetic structuring, corresponding with 4 groups clearly differentiated and highly divergent. Conversely, "C." urophthalmus showed low levels of genetic diversity and genetic differentiation, defined as 2 groups with low divergence and with no correspondence with geographical distribution. Our results show that species of cichlids parasitized by C. cichlasomae other than "C." urophthalmus, along with multiple colonization events and subsequent isolation in different basins, are likely factors that shaped the genetic structure of the parasite. Meanwhile, historical long-distance dispersal and drought periods during the Holocene, with significant population size reductions and fragmentations, are factors that could have shaped the genetic structure of the Mayan cichlid.

  18. Fanconi anemia: correlating central nervous system malformations and genetic complementation groups.

    Johnson-Tesch, Benjamin A; Gawande, Rakhee S; Zhang, Lei; MacMillan, Margaret L; Nascene, David R

    2017-06-01

    Congenital central nervous system abnormalities in children with Fanconi anemia are poorly characterized, especially with regard to specific genetic complementation groups. To characterize the impact of genetic complementation groups on central nervous system anatomy. Through chart review we identified 36 patients with Fanconi anemia with available brain MRIs at the University of Minnesota (average age, 11.3 years; range, 1-43 years; M:F=19:17), which we reviewed and compared to 19 age- and sex-matched controls (average age, 7.9 years; range, 2-18 years; M:F=9:10). Genotypic information was available for 27 patients (15 FA-A, 2 FA-C, 3 FA-G, and 7 FA-D1 [biallelic mutations in BRCA2 gene]). Of the 36 patients, 61% had at least one congenital central nervous system or skull base abnormality. These included hypoplastic clivus (n=12), hypoplastic adenohypophysis (n=11), platybasia (n=8), pontocerebellar hypoplasia (n=7), isolated pontine hypoplasia (n=4), isolated vermis hypoplasia (n=3), and ectopic neurohypophysis (n=6). Average pituitary volume was significantly less in patients with Fanconi anemia (PFanconi anemia patients (P=0.006), but the basal angle of those with FA-D1 was not significantly different from controls (P=0.239). Clivus length was less in the Fanconi anemia group (P=0.002), but significance was only observed in the FA-D1 subgroup (PFanconi anemia have higher incidences of ectopic neurohypophysis, adenohypophysis hypoplasia, platybasia and other midline central nervous system skull base posterior fossa abnormalities than age- and sex-matched controls. Patients with posterior fossa abnormalities, including pontocerebellar hypoplasia, are more likely to have biallelic BRCA2 mutations.

  19. Fanconi anemia: correlating central nervous system malformations and genetic complementation groups

    Johnson-Tesch, Benjamin A.; Gawande, Rakhee S.; Nascene, David R.; Zhang, Lei; MacMillan, Margaret L.

    2017-01-01

    Congenital central nervous system abnormalities in children with Fanconi anemia are poorly characterized, especially with regard to specific genetic complementation groups. To characterize the impact of genetic complementation groups on central nervous system anatomy. Through chart review we identified 36 patients with Fanconi anemia with available brain MRIs at the University of Minnesota (average age, 11.3 years; range, 1-43 years; M:F=19:17), which we reviewed and compared to 19 age- and sex-matched controls (average age, 7.9 years; range, 2-18 years; M:F=9:10). Genotypic information was available for 27 patients (15 FA-A, 2 FA-C, 3 FA-G, and 7 FA-D1 [biallelic mutations in BRCA2 gene]). Of the 36 patients, 61% had at least one congenital central nervous system or skull base abnormality. These included hypoplastic clivus (n=12), hypoplastic adenohypophysis (n=11), platybasia (n=8), pontocerebellar hypoplasia (n=7), isolated pontine hypoplasia (n=4), isolated vermis hypoplasia (n=3), and ectopic neurohypophysis (n=6). Average pituitary volume was significantly less in patients with Fanconi anemia (P<0.0001) than in controls. Basal angle was significantly greater in Fanconi anemia patients (P=0.006), but the basal angle of those with FA-D1 was not significantly different from controls (P=0.239). Clivus length was less in the Fanconi anemia group (P=0.002), but significance was only observed in the FA-D1 subgroup (P<0.0001). Of the seven patients meeting criteria for pontocerebellar hypoplasia, six belonged to the FA-D1 group. Patients with Fanconi anemia have higher incidences of ectopic neurohypophysis, adenohypophysis hypoplasia, platybasia and other midline central nervous system skull base posterior fossa abnormalities than age- and sex-matched controls. Patients with posterior fossa abnormalities, including pontocerebellar hypoplasia, are more likely to have biallelic BRCA2 mutations. (orig.)

  20. Fanconi anemia: correlating central nervous system malformations and genetic complementation groups

    Johnson-Tesch, Benjamin A. [University of Minnesota, Department of Radiology, Minneapolis, MN (United States); Gawande, Rakhee S.; Nascene, David R. [University of Minnesota, Department of Radiology, Neuroradiology Section, Minneapolis, MN (United States); Zhang, Lei [University of Minnesota, Biostatistical Design and Analysis Centre, Minneapolis, MN (United States); MacMillan, Margaret L. [University of Minnesota, Blood and Marrow Transplant Program, Department of Pediatrics, Minneapolis, MN (United States)

    2017-06-15

    Congenital central nervous system abnormalities in children with Fanconi anemia are poorly characterized, especially with regard to specific genetic complementation groups. To characterize the impact of genetic complementation groups on central nervous system anatomy. Through chart review we identified 36 patients with Fanconi anemia with available brain MRIs at the University of Minnesota (average age, 11.3 years; range, 1-43 years; M:F=19:17), which we reviewed and compared to 19 age- and sex-matched controls (average age, 7.9 years; range, 2-18 years; M:F=9:10). Genotypic information was available for 27 patients (15 FA-A, 2 FA-C, 3 FA-G, and 7 FA-D1 [biallelic mutations in BRCA2 gene]). Of the 36 patients, 61% had at least one congenital central nervous system or skull base abnormality. These included hypoplastic clivus (n=12), hypoplastic adenohypophysis (n=11), platybasia (n=8), pontocerebellar hypoplasia (n=7), isolated pontine hypoplasia (n=4), isolated vermis hypoplasia (n=3), and ectopic neurohypophysis (n=6). Average pituitary volume was significantly less in patients with Fanconi anemia (P<0.0001) than in controls. Basal angle was significantly greater in Fanconi anemia patients (P=0.006), but the basal angle of those with FA-D1 was not significantly different from controls (P=0.239). Clivus length was less in the Fanconi anemia group (P=0.002), but significance was only observed in the FA-D1 subgroup (P<0.0001). Of the seven patients meeting criteria for pontocerebellar hypoplasia, six belonged to the FA-D1 group. Patients with Fanconi anemia have higher incidences of ectopic neurohypophysis, adenohypophysis hypoplasia, platybasia and other midline central nervous system skull base posterior fossa abnormalities than age- and sex-matched controls. Patients with posterior fossa abnormalities, including pontocerebellar hypoplasia, are more likely to have biallelic BRCA2 mutations. (orig.)

  1. Environmental effects on allergen levels in commercially grown non-genetically modified soybeans: assessing variation across North America

    Severin E. Stevenson

    2012-08-01

    Full Text Available Soybean (Glycine max is a hugely valuable soft commodity that generates tens of billions of dollars annually. This value is due in part to the balanced composition of the seed which is roughly 1:2:2 oil, starch and protein by weight. In turn, the seeds have many uses with various derivatives appearing broadly in processed food products. As is true with many edible seeds, soybeans contain proteins that are anti-nutritional factors and allergens. Soybean, along with milk, eggs, fish, crustacean shellfish, tree nuts, peanuts and wheat, elicit a majority of food allergy reactions in the United States. Soybean seed composition can be affected by breeding, environmental conditions (e.g. temperature, moisture, insect/pathogen load, and/or soil nutrient levels. The objective of this study was to evaluate the influence of genotype and environment on allergen and anti-nutritional proteins in soybean. To address genetic and environmental effects, four varieties of non-GM soybeans were grown in six geographically distinct regions of North America (Georgia, Iowa, Kansas, Nebraska, Ontario, and Pennsylvania. Absolute quantification of proteins by mass spectrometry can be achieved with a technique called multiple reaction monitoring (MRM, during which signals from an endogenous protein are compared to those from a synthetic heavy-labeled internal standard. Using MRM, eight allergens were absolutely quantified for each variety in each environment. Statistical analyses show that for most allergens, the effects of environment far outweigh the differences between varieties brought about by breeding.

  2. Genetic diversity of giant clams (Tridacna spp.) and their associated Symbiodinium in the central Red Sea

    Pappas, Melissa

    2017-05-19

    The biodiversity of the Red Sea remains relatively understudied, particularly for invertebrate taxa. Documenting present patterns of biodiversity is essential for better understanding Red Sea reef ecosystems and how these ecosystems may be impacted by stressors (such as fishing and climate change). Several species of giant clams (genus Tridacna) are reported from the Red Sea, although the majority of research effort has occurred in the Gulf of Aqaba. We investigated the genetic diversity (16S rDNA) of the Tridacna species found in the central Saudi Arabian Red Sea. We also investigated the genetic diversity (ITS rDNA) of symbiotic dinoflagellates Symbiodinium associated with these clams. Samples were collected from nine reefs on a cross-shelf gradient near Thuwal, Saudi Arabia. Two species, T. squamosa and T. maxima, were recorded, with the latter being the most abundant. Tridacna squamosina, a species recently reported in the northern Red Sea, was not found, suggesting that this species is not present or is very rare in our study region. All tridacnids sampled were found to harbor Symbiodinium grouped in Clade A, considered an opportunistic, heat-tolerant symbiont group in anemones and corals. The consistent association with Clade A Symbiodinium in central Red Sea tridacnids may reflect the consequence of adaptation to the relatively extreme conditions of the Red Sea. This study contributes to an ever-growing catalog of Red Sea biodiversity and serves as important baseline information for a region experiencing dynamic pressures.

  3. Geology of gemstone deposit Ugljarevats (Central Serbia) and contributions to genetic model

    Kureshevicj, Lidija; Vushovicj, Olivera; Delicj-Nikolicj, Ivana

    2017-01-01

    Silica gemstone deposit Ugljarevats is situated within the ophiolite sequence of the Vardar zone central deep fault. Genetic processes of this deposit are connected to the Neogene calc-alkaline magmatic activity of the Vardar zone and hydrothermal activity triggered by it. Based on surface occurrences of listwenitized serpentinite containing silica mineralization, it can be inferred that the ore body is an elongated oval stock. Within the stock of hydrothermally altered serpentinite, the gemstone mineralization occurs as veins, stock works and irregular bodies. Present gemstone types include chalcedony varieties (jasper, colourless and greenish chalcedony, carnelian and sard) and opal (opalized serpentinite). Homogenous pieces are very rare. Most often, various types of silica are intimately intermixed and combined. The mineralization has formed in two distinct hydrothermal phases, apparently in close time succession. Jasper and coloured chalcedony (and rare magnesite) are the products of the first phase of hydro- thermal activity, while the colourless chalcedony is formed in the second phase. Newly discovered type of silica vein with central-symmetrical parallel banding gives new contributions to a genetic model, proving the precipitation process and its products are unpredictably changeable, heterogeneous and depending on the evolution of the local environment physico-chemical conditions, notably the contents of impurities and system's openness degree. (author)

  4. Molecular genetic variation in sheep of the central Volga area inhabited by Finno-Ugric peoples

    M. TAPIO

    2008-12-01

    Full Text Available Based on morphology, native northern European sheep breeds belong to the short tailed type, of which the Romanov is the only native example still distributed in northwest Russia. Besides this, there exist local sheep populations kept by Finno-Ugric peoples in the central Volga region, which represent additional genetic resources in the area. Four sheep populations from the central Volga region were genotyped for 20 microsatellites and compared with geographically proximate breeds (Estonian Whitehead and Blackhead, the Finnsheep and an exported and a native population of Russian Romanov and with local populations in Estonia, Finland and Russian Karelia. Between-breed analyses including admixture analysis using molecular genetic markers and the phenotypic characteristics indicated that the Volgaic populations have not remained pure. The Viena population from Russian Karelia, the Romanov breed and, to some extent, the Komi population, have escaped extensive mixing, making them most attractive for conservation programmes. The study compared imported and native Romanov breed populations and the results suggest that the diversity parameters are markedly similar in these two populations.;

  5. Genetic diversity of giant clams (Tridacna spp.) and their associated Symbiodinium in the central Red Sea

    Pappas, Melissa; He, Song; Hardenstine, Royale; Kanee, Hana; Berumen, Michael L.

    2017-01-01

    The biodiversity of the Red Sea remains relatively understudied, particularly for invertebrate taxa. Documenting present patterns of biodiversity is essential for better understanding Red Sea reef ecosystems and how these ecosystems may be impacted by stressors (such as fishing and climate change). Several species of giant clams (genus Tridacna) are reported from the Red Sea, although the majority of research effort has occurred in the Gulf of Aqaba. We investigated the genetic diversity (16S rDNA) of the Tridacna species found in the central Saudi Arabian Red Sea. We also investigated the genetic diversity (ITS rDNA) of symbiotic dinoflagellates Symbiodinium associated with these clams. Samples were collected from nine reefs on a cross-shelf gradient near Thuwal, Saudi Arabia. Two species, T. squamosa and T. maxima, were recorded, with the latter being the most abundant. Tridacna squamosina, a species recently reported in the northern Red Sea, was not found, suggesting that this species is not present or is very rare in our study region. All tridacnids sampled were found to harbor Symbiodinium grouped in Clade A, considered an opportunistic, heat-tolerant symbiont group in anemones and corals. The consistent association with Clade A Symbiodinium in central Red Sea tridacnids may reflect the consequence of adaptation to the relatively extreme conditions of the Red Sea. This study contributes to an ever-growing catalog of Red Sea biodiversity and serves as important baseline information for a region experiencing dynamic pressures.

  6. Scale-dependent effects of a heterogeneous landscape on genetic differentiation in the Central American squirrel monkey (Saimiri oerstedii.

    Mary E Blair

    Full Text Available Landscape genetic studies offer a fine-scale understanding of how habitat heterogeneity influences population genetic structure. We examined population genetic structure and conducted a landscape genetic analysis for the endangered Central American Squirrel Monkey (Saimiri oerstedii that lives in the fragmented, human-modified habitats of the Central Pacific region of Costa Rica. We analyzed non-invasively collected fecal samples from 244 individuals from 14 groups for 16 microsatellite markers. We found two geographically separate genetic clusters in the Central Pacific region with evidence of recent gene flow among them. We also found significant differentiation among groups of S. o. citrinellus using pairwise F(ST comparisons. These groups are in fragments of secondary forest separated by unsuitable "matrix" habitats such as cattle pasture, commercial African oil palm plantations, and human residential areas. We used an individual-based landscape genetic approach to measure spatial patterns of genetic variance while taking into account landscape heterogeneity. We found that large, commercial oil palm plantations represent moderate barriers to gene flow between populations, but cattle pastures, rivers, and residential areas do not. However, the influence of oil palm plantations on genetic variance was diminished when we restricted analyses to within population pairs, suggesting that their effect is scale-dependent and manifests during longer dispersal events among populations. We show that when landscape genetic methods are applied rigorously and at the right scale, they are sensitive enough to track population processes even in species with long, overlapping generations such as primates. Thus landscape genetic approaches are extremely valuable for the conservation management of a diverse array of endangered species in heterogeneous, human-modified habitats. Our results also stress the importance of explicitly considering the heterogeneity of

  7. Development and application of microsatellites in Carcinus maenas: genetic differentiation between Northern and Central Portuguese populations.

    Sónia Pascoal

    Full Text Available Carcinus maenas, the common shore crab of European coastal waters, has recently gained notoriety due to its globally invasive nature associated with drastic ecological and economic effects. The native ubiquity and worldwide importance of C. maenas has resulted in it becoming one of the best-studied estuarine crustacean species globally. Accordingly, there is significant interest in investigating the population genetic structure of this broadly distributed crab along European and invaded coastlines. Here, we developed polymerase chain reaction (PCR primers for one dinucleotide and two trinucleotide microsatellite loci, resulting from an enrichment process based on Portuguese populations. Combining these three new markers with six existing markers, we examined levels of genetic diversity and population structure of C. maenas in two coastal regions from Northern and Central Portugal. Genotypes showed that locus polymorphism ranged from 10 to 42 alleles (N = 135 and observed heterozygosity per locus ranged from 0.745 to 0.987 with expected heterozygosity ranging from 0.711 to 0.960; values typical of marine decapods. The markers revealed weak, but significant structuring among populations (global F(ST = 0.004 across a 450 km (over-water distance spatial scale. Combinations of these and existing markers will be useful for studying population genetic parameters at a range of spatial scales of C. maenas throughout its expanding species range.

  8. Dissecting the genetic architecture of frost tolerance in Central European winter wheat.

    Zhao, Yusheng; Gowda, Manje; Würschum, Tobias; Longin, C Friedrich H; Korzun, Viktor; Kollers, Sonja; Schachschneider, Ralf; Zeng, Jian; Fernando, Rohan; Dubcovsky, Jorge; Reif, Jochen C

    2013-11-01

    Abiotic stress tolerance in plants is pivotal to increase yield stability, but its genetic basis is still poorly understood. To gain insight into the genetic architecture of frost tolerance, this work evaluated a large mapping population of 1739 wheat (Triticum aestivum L.) lines and hybrids adapted to Central Europe in field trials in Germany and fingerprinted the lines with a 9000 single-nucleotide polymorphism array. Additive effects prevailed over dominance effects. A two-dimensional genome scan revealed the presence of epistatic effects. Genome-wide association mapping in combination with a robust cross-validation strategy identified one frost tolerance locus with a major effect located on chromosome 5B. This locus was not in linkage disequilibrium with the known frost loci Fr-B1 and Fr-B2. The use of the detected diagnostic markers on chromosome 5B, however, does not allow prediction of frost tolerance with high accuracy. Application of genome-wide selection approaches that take into account also loci with small effect sizes considerably improved prediction of the genetic variation of frost tolerance in wheat. The developed prediction model is valuable for improving frost tolerance because this trait displays a wide variation in occurrence across years and is therefore a difficult target for conventional phenotypic selection.

  9. On the Development of Multi-Hazard Early Warning Networks: Practical experiences from North and Central America.

    Mencin, David; Hodgkinson, Kathleen; Braun, John; Meertens, Charles; Mattioli, Glen; Phillips, David; Blume, Fredrick; Berglund, Henry; Fox, Otina; Feaux, Karl

    2015-04-01

    The GAGE facility, managed by UNAVCO, maintains and operates about 1300 GNSS stations distributed across North and Central America as part of the EarthScope Plate Boundary Observatory (PBO) and the Continuously Operating Caribbean GPS Observational Network (COCONet). UNAVCO has upgraded about 450 stations in these networks to real-time and high-rate (RT-GNSS) and included surface meteorological instruments. The majority of these streaming stations are part of the PBO but also include approximately 50 RT-GNSS stations in the Caribbean and Central American region as part of the COCONet and TLALOCNet projects. Based on community input UNAVCO has been exploring ways to increase the capability and utility of these resources to improve our understanding in diverse areas of geophysics including seismic, volcanic, magmatic and tsunami deformation sources, extreme weather events such as hurricanes and storms, and space weather. The RT-GNSS networks also have the potential to profoundly transform our ability to rapidly characterize geophysical events, provide early warning, as well as improve hazard mitigation and response. Specific applications currently under development with university, commercial, non-profit and government collaboration on national and international scales include earthquake and tsunami early warning systems and near real-time tropospheric modeling of hurricanes and precipitable water vapor estimate assimilation. Using tsunami early warning as an example, an RT-GNSS network can provide multiple inputs in an operational system starting with rapid assessment of earthquake sources and associated deformation which informs the initial modeled tsunami. The networks can then can also provide direct measurements of the tsunami wave heights and propagation by tracking the associated ionospheric disturbance from several 100's of km away as the waves approaches the shoreline. These GNSS based constraints can refine the tsunami and inundation models and potentially

  10. Linking National Parks with its Gateway Communities for Tourism Development in Central America: Nindiri, Nicaragua, Bagazit, Costa Rica and Portobelo, Panama

    Aguirre G., J. A.

    2006-01-01

    Full Text Available Protected areas and national parks are becoming one of the most important forms of land use in Central America. All the projections made by the World Tourism Organization seems to agree that by 2010 Central America, maybe receiving between eight and ten millions tourists, a figure that is almost twice what the region is receiving today. A study was conducted base on 369 direct field surveys conducted in three Central American communities: Bagazit gateway community to Palo Verde National Park, Costa Rica, Nindiri, gateway community to Volcan Masaya National Park, Nicaragua and Portobelo, gateway community to Por-tobelo National Park, Panama. The study found that relative to the socio-demographic variables, that there were no significance differences at the 95% probability level in all four variables, age, sex, education and monthly income of the family. Educational level seems to be the socio-demographic variables affecting more the state of relations. The perception variable being has taken into account in the decision that affects the communities and responsibility to help with community problems are present in two of the three models. The perception variables related to tourism, feel trained to take care of the tourist and existence of businesses that can caters to tourist seem to be key elements in the community perception about the state of relation. Tourism related economic activities and community participation in park decisions are today and will be in the future essential elements in the shaping of community/park relations in Central America as tourism becomes a major economic sector in the region economy.

  11. Genetic response to metabolic fluctuations: correlation between central carbon metabolism and DNA replication in Escherichia coli

    Szalewska-Pałasz Agnieszka

    2011-03-01

    Full Text Available Abstract Background Until now, the direct link between central carbon metabolism and DNA replication has been demonstrated only in Bacillus. subtilis. Therefore, we asked if this is a specific phenomenon, characteristic for this bacterium and perhaps for its close relatives, or a more general biological rule. Results We found that temperature-sensitivity of mutants in particular genes coding for replication proteins could be suppressed by deletions of certain genes coding for enzymes of the central carbon metabolism. Namely, the effects of dnaA46(ts mutation could be suppressed by dysfunction of pta or ackA, effects of dnaB(ts by dysfunction of pgi or pta, effects of dnaE486(ts by dysfunction of tktB, effects of dnaG(ts by dysfunction of gpmA, pta or ackA, and effects of dnaN159(ts by dysfunction of pta or ackA. The observed suppression effects were not caused by a decrease in bacterial growth rate. Conclusions The genetic correlation exists between central carbon metabolism and DNA replication in the model Gram-negative bacterium, E. coli. This link exists at the steps of initiation and elongation of DNA replication, indicating the important global correlation between metabolic status of the cell and the events leading to cell reproduction.

  12. Geological implications of recently derived vertical velocities of benchmarks of the south-central United States of America

    Dokka, R. K.

    2005-05-01

    It has been long-recognized that the south-central United States of America bordering the Gulf of Mexico (GOM) is actively subsiding, resulting in a slow, yet unrelenting inundation of the coast from south Texas to southwestern Alabama. Today's motions are but the latest chapter in the subsidence history of the GOM, a region that has accommodated the deposition of over 20 km of deltaic and continental margin sediments since mid Mesozoic time. Understanding the recent history of displacements and the processes responsible for subsidence are especially critical for near-term planning for coastal protection and restoration activities. Documentation of the true magnitude and geography of vertical motions of the surface through time has been hampered because previous measurement schemes did not employ reference datums of sufficient spatial and temporal precision. This situation has been somewhat improved recently through the recent analysis of National Geodetic Survey (NGS) 1st order leveling data from >2710 benchmarks in the region by Shinkle and Dokka (NOAA Technical Report 50 [2004]). That paper used original observations (not adjusted) and computed displacements and velocities related to NAVD88 for benchmarks visited during various leveling surveys from 1920 through 1995. Several important characteristics were observed and are summarized below. First, the data show that subsidence is not limited to areas of recent sediment accumulation such as the wetland areas of the modern delta (MRD) of the Mississippi River or its upstream alluvial valley (MAV), as supposed by most current syntheses. The entire coastal zone, as well as inland areas several hundred km from the shore, has subsided over the period of measurement. Regionally, vertical velocities range from less than -52 mm/yr in Louisiana to over +15 mm/yr in peripheral areas of eastern Mississippi-Alabama. The mean rate is ~-11 mm/yr in most coastal parishes of Louisiana. In the Mississippi River deltaic plain

  13. The 1.1-Ga Midcontinent Rift System, central North America: sedimentology of two deep boreholes, Lake Superior region

    Ojakangas, Richard W.; Dickas, Albert B.

    2002-03-01

    The Midcontinent Rift System (MRS) of central North America is a 1.1-Ga, 2500-km long structural feature that has been interpreted as a triple-junction rift developed over a mantle plume. As much as 20 km of subaerial lava flows, mainly flood basalts, are overlain by as much as 10 km of sedimentary rocks that are mostly continental fluvial red beds. This rock sequence, known as the Keweenawan Supergroup, has been penetrated by a few deep boreholes in the search for petroleum. In this paper, two deep boreholes in the Upper Peninsula of Michigan are described in detail for the first time. Both the Amoco Production #1-29R test, herein referred to as the St. Amour well, and the nearby Hickey Creek well drilled by Cleveland Cliffs Mining Services, were 100% cored. The former is 7238 ft (2410 m) deep and the latter is 5345 ft (1780 m) deep. The entirety of the stratigraphic succession of the Hickey Creek core correlates very well with the upper portion of the St. Amour core, as determined by core description and point-counting of 43 thin sections selected out of 100 studied thin sections. Two Lower Paleozoic units and two Keweenawan red bed units—the Jacobsville Sandstone and the underlying Freda Sandstone—are described. The Jacobsville is largely a feldspatholithic sandstone and the Freda is largely a lithofeldspathic sandstone. Below the Freda, the remaining footage of the St. Amour core consists of a thick quartzose sandstone unit that overlies a heterogenous unit of intercalated red bed units of conglomerate, sandstone, siltstone, and shale; black shale; individual basalt flows; and a basal ignimbritic rhyolite. This lower portion of the St. Amour core presents an enigma, as it correlates very poorly with other key boreholes located to the west and southwest. While a black shale sequence is similar to the petroleum-bearing Nonesuch Formation farther west, there is no conglomerate unit to correlate with the Copper Harbor Conglomerate. Other key boreholes are

  14. Crop yield, genetic parameter estimation and selection of sacha inchi in central Amazon

    Mágno Sávio Ferreira Valente

    2017-06-01

    Full Text Available In Brazil, sacha inchi oil is produced by hand from plant materials with no breeding or detailed information about the chemical composition of seeds. In addition, most of the current information on the agronomic traits of this species originates from research carried out in the Peruvian Amazon. In order to promote the research and cultivation of sacha inchi in the Brazilian territory, this study aimed to analyze, in the central Amazon region, different accessions of this oilseed for characteristics of production and quality of fruits and seeds, as well as to estimate genetic parameters, through mixed models, with identification of superior accessions, for breeding purposes. A total of 37 non-domesticated accessions were evaluated in a randomized block design, with five replications and two plants per plot. The average oil content in seeds was 29.07 % and unsaturated fatty acids amounted to 91.5 % of the total fat content. For the yield traits, the estimates of individual broad-sense heritability were moderate (~0.33, while the heritability based on the average of progenies resulted in a selective accuracy of approximately 0.85. The use of the selection index provided simultaneous gains for yield traits (> 40 % and oil yield. A high genetic variability was observed for the main traits of commercial interest for the species, as well as promising perspectives for the development of superior varieties for agro-industrial use.

  15. Agrobiodiversity and genetic erosion of crop varieties and plant resources in the Central Great Caucasus

    Maia Akhalkatsi

    2017-03-01

    Full Text Available Kazbegi Municipality is located in the Central Great Caucasus at an altitude between 1250 and 5047 m a.s.l. Agriculture of this area is extreme internal variability and complexity, with a multiplicity of highly localized providing the habitats and agricultural lands for much genetic erosion of crop varieties, animals, plants, fungi, and other life forms for wild plant resources. Historically, Kazbegi producers had begun cultivating the land to prepare for planting in of distribution local varieties of wheat, barley, rye, oats, etc. In the only cereals, legumes, herbs and some fruits are cultivated in alpine zone as the upper limit till the location of 2160 m a.s.l. Genetic erosion has been determined historically of aboriginal crops from sheep and cattle grazing problem and reached extreme levels from 1970s in Kazbegi Municipality and causes a problem to maintain agriculture. Plant resources remained in forests and subalpine grasslands and shrub lands. The problems of these materials are habitat degradation by disturbance in many forest types with destroyed and burned. Tree seedlings are grazing by animals and forest is not restoring naturally. Forest planting is good relation for restoration of plant wild species resources. Investigation on exchange on mountain agriculture and plant resources will now be rapidly accelerated in the vital interests of mountain communities.

  16. Population genetics of Glossina palpalis palpalis from central African sleeping sickness foci

    Solano Philippe

    2011-07-01

    Full Text Available Abstract Background Glossina palpalis palpalis (Diptera: Glossinidae is widespread in west Africa, and is the main vector of sleeping sickness in Cameroon as well as in the Bas Congo Province of the Democratic Republic of Congo. However, little is known on the structure of its populations. We investigated G. p. palpalis population genetic structure in five sleeping sickness foci (four in Cameroon, one in Democratic Republic of Congo using eight microsatellite DNA markers. Results A strong isolation by distance explains most of the population structure observed in our sampling sites of Cameroon and DRC. The populations here are composed of panmictic subpopulations occupying fairly wide zones with a very strong isolation by distance. Effective population sizes are probably between 20 and 300 individuals and if we assume densities between 120 and 2000 individuals per km2, dispersal distance between reproducing adults and their parents extends between 60 and 300 meters. Conclusions This first investigation of population genetic structure of G. p. palpalis in Central Africa has evidenced random mating subpopulations over fairly large areas and is thus at variance with that found in West African populations of G. p. palpalis. This study brings new information on the isolation by distance at a macrogeographic scale which in turn brings useful information on how to organise regional tsetse control. Future investigations should be directed at temporal sampling to have more accurate measures of demographic parameters in order to help vector control decision.

  17. Genetic structure analysis of Spirometra erinaceieuropaei isolates from central and southern China.

    Xi Zhang

    Full Text Available Sparganosis caused by invasion of the plerocercoid larvae (spargana of Spirometra erinaceieuropaei have increased in recent years in China. However, the population genetic structure regarding this parasite is still unclear. In this study, we used the sequences of two mitochondrial genes cytochrome b (cytb and cytochrome c oxidase subunit I (cox1 to analyze genetic variation and phylogeographic structure of the S. erinaceieuropaei populations.A total of 88 S. erinaceieuropaei isolates were collected from naturally infected frogs in 14 geographical locations of China. The complete cytb and cox1 genes of each sample was amplified and sequenced. Total 61 haplotypes were found in these 88 concatenated sequences. Each sampled population and the total population have high haplotype diversity (Hd, accompanied by very low nucleotide diversity (Pi. Phylogenetic analyses of haplotypes revealed two distinct clades (HeN+HuN+GZ-AS clade and GX+HN+GZ-GY clade corresponding two sub-networks yielded by the median-joining network. Pairwise FST values supported great genetic differentiation between S. erinaceieuropaei populations. Both negative Fu's FS value of neutrality tests and unimodal curve of mismatch distribution analyses supported demographic population expansion in the HeN+HuN+GZ-AS clade. The BEAST analysis showed that the divergence time between the two clades took place in the early Pleistocene (1.16 Myr, and by Bayesian skyline plot (BSP an expansion occurred after about 0.3 Myr ago.S. erinaceieuropaei from central and southern China has significant phylogeographic structure, and climatic oscillations during glacial periods in the Quaternary may affect the demography and diversification of this species.

  18. Central Bank autonomy in Europe and Latin America: analysis of differences and applications Autonomía de la banca central en Europa y América Latina

    Rollinat Robert

    1996-06-01

    Full Text Available This article makes a comparative analysis of the experiences of the independent central bank in Latin America and Europe. After reviewing the problems and theories of central bank autonomy, it studies the recent evolution of the Latin American central bank in comparison with the European central bank, high lights the perverse effects of the reforms, and shows that their objective is more the stability of the financial system than the stability of prices. Finally, it describes the tests to which the new Latin American central banks have been subjected and the effects on their credibility. It concludes that these entities have had to correct and pay for the incoherences and errors of the market, and that their independence or autonomy depends on their continuing to ful fill this role, not only for economíc or monetary reasons but for the needs of political and social democracy.Este artículo hace un análisis comparativo de las experiencias de la banca central independiente en América Latina y Europa. Después de revisar los problemas y las teorías de la autonompia de los bancos centrales, estudia la reciente evolución de la banca central latinoamericana en comparación con la europea, destaca los efectos perversos de estas reformas u muestra que sus objetivo es más la estabilidad del sistema financiero que la de los precios. Finalmente, describe las pruebas a que han sido sometidos los nuevos bancos centrales latinomaericanos y los efectos de sus credibilidad. Concluye que estas entidades han tenido que corregir y pagar las incoherencias y los errrores del mercado, y que su 'independencia' o autonomía depende de que sigan cumpliendo con ese papel no sólo por razones económicas o monetarias sino por las necesidades de la democracia política y social.

  19. The Development of improved willow clones for eastern North America

    R. F. Kopp; L. B. Smart; C. A. Maynard; J. G. Isebrands; G. A. Tuskan; L. P. Abrahamson

    2001-01-01

    Efforts aimed at genetic improvement of Salix are increasing in North America.Most of these are directed towards developing improved clones for biomass production, phytoremediation, nutrient filters, and stream bank stabilization in the Northeast and North-central United States. Native species are of primary interest, but a small number of clones containing non-native...

  20. Mapping occurrence of Taenia solium taeniosis/cysticercosis and areas at risk of porcine cysticercosis in Central America and the Caribbean basin.

    Braae, Uffe Christian; Devleesschauwer, Brecht; Sithole, Fortune; Wang, Ziqi; Willingham, Arve Lee

    2017-09-18

    This study aimed to map the occurrence of Taenia solium taeniosis/cysticercosis at national level within Central America and the Caribbean basin, and to map the distribution of porcine cysticercosis at first-level administrative subdivision level (department level) and the porcine population at risk. This zoonotic parasite is believed to be widely endemic across most of Latin America. However, there is little information readily available for Central America and the Caribbean basin. Taenia solium has been ranked the most important foodborne parasitic hazard globally and within endemic areas is a common cause of preventable epilepsy. We conducted a structured literature search in PubMed, supplemented and crossed-referenced with relevant academic databases, grey literature, and active searches in identified literature, to identify all records of T. solium presence in Central America and the Caribbean basin between 1986 and April 2017. To retrieve grey literature, government entities, researchers and relevant institutions across the region were contacted in an attempt to cover all countries and territories. Identified records containing data on porcine cysticercosis were geo-referenced to identify department level distribution and compared to modelled distributions of pigs reared under extensive production systems. We identified 51 records of T. solium at the national level, covering 13 countries and an additional three countries were included based on World Organisation for Animal Health (OIE) reports, giving a total of 16 countries out of 41 with evidence of the parasite's presence. Screening records for porcine cysticercosis data at the departmental level confirmed porcine cysticercosis presence in 11 departments across six countries (Colombia, Guatemala, Honduras, Mexico, Nicaragua and Venezuela). When comparing these results to areas where pigs were kept in extensive production systems and areas where no information on porcine cysticercosis exists, it is apparent

  1. Fiesta! Mexico and Central America: A Global Awareness Program for Children in Grades 2-5. Bridges between Nations Series.

    Linse, Barbara; Judd, Dick

    Mexican and Central American cultures are a blend of Native American influences and Spanish traditions and religions. These are seen in aspects of Mexican and Central American celebrations. This book explores those celebrations through activities in art, folk and classical music, dances and fiestas. The book is organized into two sections to…

  2. The Role of Long-Term Tectonic Deformation on the Distribution of Present-Day Seismic Activity in the Caribbean and Central America

    Schobelock, J.; Stamps, D. S.; Pagani, M.; Garcia, J.; Styron, R. H.

    2017-12-01

    The Caribbean and Central America region (CCAR) undergoes the entire spectrum of earthquake types due to its complex tectonic setting comprised of transform zones, young oceanic spreading ridges, and subductions along its eastern and western boundaries. CCAR is, therefore, an ideal setting in which to study the impacts of long-term tectonic deformation on the distribution of present-day seismic activity. In this work, we develop a continuous tectonic strain rate model based on inter-seismic geodetic data and compare it with known active faults and earthquake focal mechanism data. We first create a 0.25o x 0.25o finite element mesh that is comprised of block geometries defined in previously studies. Second, we isolate and remove transient signals from the latest open access community velocity solution from UNAVCO, which includes 339 velocities from COCONet and TLALOCNet GNSS data for the Caribbean and Central America, respectively. In a third step we define zones of deformation and rigidity by creating a buffer around the boundary of each block that varies depending on the size of the block and the expected deformation zone based on locations of GNSS data that are consistent with rigid block motion. We then assign each node within the buffer a 0 for the deforming areas and a plate index outside the buffer for the rigid. Finally, we calculate a tectonic strain rate model for CCAR using the Haines and Holt finite element approach to fit bi-cubic Bessel splines to the the GNSS/GPS data assuming block rotation for zones of rigidity. Our model of the CCAR is consistent with compression along subduction zones, extension across the mid-Pacific Rise, and a combination of compression and extension across the North America - Caribbean plate boundary. The majority of CCAR strain rate magnitudes range from -60 to 60 nanostrains/yr. Modeling results are then used to calculate expected faulting behaviors that we compare with mapped geologic faults and seismic activity.

  3. Oral Manifestations of Tropical Infectious Diseases of Central and South America. Part II. Bacterial and Mycotic Infections.

    1979-05-24

    resemble pulmonary tuberculosis , in which 8% of the patients develop ora l or pha ryngea l lesions. In patients with disseminated paracocc idioido...ions , par t icularl y Mexico , Panama , and northern South America .1 The disease occurs most fre- quentl y before the age of ten years and is rare...30-50 years of age.7’’8 Infect i on most comon l y occurs through inhalation of spores resulting in a pulmonary infection which may or may not become

  4. Use of linkage mapping and centrality analysis across habitat gradients to conserve connectivity of gray wolf populations in western North America.

    Carroll, Carlos; McRae, Brad H; Brookes, Allen

    2012-02-01

    . Centrality analysis is relevant to conservation and landscape genetics at a range of spatial extents, but it may be most broadly applicable within single- and multispecies planning efforts to conserve regional habitat connectivity. ©2011 Society for Conservation Biology.

  5. A Common Genetic Origin for Early Farmers from Mediterranean Cardial and Central European LBK Cultures.

    Olalde, Iñigo; Schroeder, Hannes; Sandoval-Velasco, Marcela; Vinner, Lasse; Lobón, Irene; Ramirez, Oscar; Civit, Sergi; García Borja, Pablo; Salazar-García, Domingo C; Talamo, Sahra; María Fullola, Josep; Xavier Oms, Francesc; Pedro, Mireia; Martínez, Pablo; Sanz, Montserrat; Daura, Joan; Zilhão, João; Marquès-Bonet, Tomàs; Gilbert, M Thomas P; Lalueza-Fox, Carles

    2015-12-01

    The spread of farming out of the Balkans and into the rest of Europe followed two distinct routes: An initial expansion represented by the Impressa and Cardial traditions, which followed the Northern Mediterranean coastline; and another expansion represented by the LBK (Linearbandkeramik) tradition, which followed the Danube River into Central Europe. Although genomic data now exist from samples representing the second migration, such data have yet to be successfully generated from the initial Mediterranean migration. To address this, we generated the complete genome of a 7,400-year-old Cardial individual (CB13) from Cova Bonica in Vallirana (Barcelona), as well as partial nuclear data from five others excavated from different sites in Spain and Portugal. CB13 clusters with all previously sequenced early European farmers and modern-day Sardinians. Furthermore, our analyses suggest that both Cardial and LBK peoples derived from a common ancient population located in or around the Balkan Peninsula. The Iberian Cardial genome also carries a discernible hunter-gatherer genetic signature that likely was not acquired by admixture with local Iberian foragers. Our results indicate that retrieving ancient genomes from similarly warm Mediterranean environments such as the Near East is technically feasible. © The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  6. Hepatitis C virus prevalence and genetic diversity among pregnant women in Gabon, central Africa

    Mahé Antoine

    2008-06-01

    Full Text Available Abstract Background Hepatitis C virus (HCV infection is a major global public health problem in both developed and developing countries. The prevalence and genetic diversity of HCV in pregnant women in Gabon, central Africa, is not known. We therefore evaluated the prevalence and the circulating genotypes of HCV in a large population cohort of pregnant women. Methods Blood samples (947 were collected from pregnant women in the five main cities of the country. The prevalence was evaluated by two ELISA tests, and the circulating genotypes were characterized by sequencing and phylogenetic analysis. Results Twenty pregnant women (2.1% were infected with HCV. The seroprevalence differed significantly by region (p = 0.004 and increased significantly with age (p = 0.05, being 1.3% at 14–20 years, 1.1% at 21–25 years, 1.9% at 26–30 years, 4.1% at 31–35 years and 6.0% at > 35 years. Sequencing in the 5'-UTR and NS5B regions showed that the circulating strains belonged to genotypes 4 (4e and 4c. Conclusion We found that the HCV seroprevalence in pregnant women in Gabon is almost as high as that in other African countries and increases with age. Furthermore, only genotype 4 (4e and 4c was found. More extensive studies aiming to evaluate the prevalence and heterogeneity of HCV genotypes circulating in the general population of the country are needed.

  7. New views on American colonization: critical tests from South America

    O'Rourke, Dennis

    2007-01-01

    Full Text Available The traditional view of colonization of the Americas as a migration across Beringia and subsequent dispersal southward following the last glacial maximum is being increasingly questioned. In North America, archaeological links to Siberia are tenuous and genetic data are more consistent with an earlier entry of people into the Americas, from Central rather than Northeast Siberia. An entry of populations into the Americas prior to the last glacial maximum forces a reconsideration not only of timing, but also geographic points of entry and speed of dispersal, based on ecological theory. A number of emerging alternative hypotheses on the colonization of the Americas predict early entry and dispersal of people into South America - earlier than, or coeval with, initial dispersal in North America. The study of genetic, morphological, and archaeological variation across South America is critical to testing these new, alternative hypotheses of Native American origins. I will review the evidence for emerging, alternative views of American Colonization, and suggest ways in which data from South American populations and prehistory will be crucial in testing them.

  8. Variability and population genetic structure in Achyrocline flaccida (Weinm. DC., a species with high value in folk medicine in South America.

    Juliana da Rosa

    Full Text Available Better knowledge of medicinal plant species and their conservation is an urgent need worldwide. Decision making for conservation strategies can be based on the knowledge of the variability and population genetic structure of the species and on the events that may influence these genetic parameters. Achyrocline flaccida (Weinm. DC. is a native plant from the grassy fields of South America with high value in folk medicine. In spite of its importance, no genetic and conservation studies are available for the species. In this work, microsatellite and ISSR (inter-simple sequence repeat markers were used to estimate the genetic variability and structure of seven populations of A. flaccida from southern Brazil. The microsatellite markers were inefficient in A. flaccida owing to a high number of null alleles. After the evaluation of 42 ISSR primers on one population, 10 were selected for further analysis of seven A. flaccida populations. The results of ISSR showed that the high number of exclusive absence of loci might contribute to the inter-population differentiation. Genetic variability of the species was high (Nei's diversity of 0.23 and Shannon diversity of 0.37. AMOVA indicated higher genetic variability within (64.7% than among (33.96% populations, and the variability was unevenly distributed (FST 0.33. Gene flow among populations ranged from 1.68 to 5.2 migrants per generation, with an average of 1.39. The results of PCoA and Bayesian analyses corroborated and indicated that the populations are structured. The observed genetic variability and population structure of A. flaccida are discussed in the context of the vegetation formation history in southern Brazil, as well as the possible anthropogenic effects. Additionally, we discuss the implications of the results in the conservation of the species.

  9. High genetic diversity among and within bitter manioc varieties cultivated in different soil types in Central Amazonia

    Alessandro Alves-Pereira

    2017-04-01

    Full Text Available Abstract Although manioc is well adapted to nutrient-poor Oxisols of Amazonia, ethnobotanical observations show that bitter manioc is also frequently cultivated in the highly fertile soils of the floodplains and Amazonian dark earths (ADE along the middle Madeira River. Because different sets of varieties are grown in each soil type, and there are agronomic similarities between ADE and floodplain varieties, it was hypothesized that varieties grown in ADE and floodplain were more closely related to each other than either is to varieties grown in Oxisols. We tested this hypothesis evaluating the intra-varietal genetic diversity and the genetic relationships among manioc varieties commonly cultivated in Oxisols, ADE and floodplain soils. Genetic results did not agree with ethnobotanical expectation, since the relationships between varieties were variable and most individuals of varieties with the same vernacular name, but grown in ADE and floodplain, were distinct. Although the same vernacular name could not always be associated with genetic similarities, there is still a great amount of variation among the varieties. Many ecological and genetic processes may explain the high genetic diversity and differentiation found for bitter manioc varieties, but all contribute to the maintenance and amplification of genetic diversity within the manioc in Central Amazonia.

  10. Working Together to Make a Difference in Rural America: North Central Regional Center for Rural Development, 2010 Annual Report

    North Central Regional Center for Rural Development, 2011

    2011-01-01

    The North Central Regional Center for Rural Development (NCRCRD) is one of four regional centers in the United States that have worked to improve the quality of life in rural communities for nearly 40 years. With funding from the USDA National Institute of Food and Agriculture and the land-grant universities in our 12-state region, the NCRCRD…

  11. Education for Management in Central America. The Role of the Library of the Instituto Centroamericano de Administracion de Empresas

    Bloch, Thomas

    1973-01-01

    The institute, established in 1968, is a multinational organization for education in management at the post-graduate level. Its library, with five staff members, now has 4,000 volumes and receives 300 periodical publications: it should eventually become a Central American business and economic management information and research center. (Author/SJ)

  12. The University as Agent of Social Transformation: The Case of the University of Central America in El Salvador

    Valiente, Orfilio Ernesto

    2015-01-01

    In 1965, the Jesuit-run Central American University (UCA) was launched in El Salvador as the wealthy family's educational alternative to the increasingly leftist National University. But within a decade, the UCA would shift its focus to the inequalities and injustice experienced by the country's popular majorities and to its own role as society's…

  13. Genetic structure of Octopus vulgaris (Cephalopoda, Octopodidae) in the central Mediterranean Sea inferred from the mitochondrial COIII gene.

    Fadhlaoui-Zid, Karima; Knittweis, Leyla; Aurelle, Didier; Nafkha, Chaala; Ezzeddine, Soufia; Fiorentino, Fabio; Ghmati, Hisham; Ceriola, Luca; Jarboui, Othman; Maltagliati, Ferruccio

    2012-01-01

    The polymorphism of the mitochondrial gene cytochrome oxidase III was studied in the Mediterranean octopus, Octopus vulgaris Cuvier, 1797. A total of 202 specimens from seven sampling sites were analysed with the aim of elucidating patterns of genetic structure in the central Mediterranean Sea and to give an insight into the phylogeny of the Octopus genus. Phylogenetic analyses showed that individuals from the central Mediterranean belong to the O. vulgaris species whose limits should nevertheless be clarified. Concerning genetic structure, two high-frequency haplotypes were present in all locations. The overall genetic divergence (Φ(ST)=0.05, P<0.05) indicated a significant genetic structuring in the study area and an AMOVA highlighted a significant break between western and eastern Mediterranean basins (Φ(CT)=0.094, P<0.05). Possible explanations for the observed patterns of genetic structuring are discussed with reference to their relevance for fisheries management. Copyright © 2012. Published by Elsevier SAS.

  14. First record of the oak gall wasp genus Neuroterus Hartig, 1840 (Hymenoptera, Cynipidae, Cynipini from Central America with description of three new species from Panama and Costa Rica

    E. Medianero

    2017-05-01

    Full Text Available Three new species of Neuroterus Hartig, 1840 (Hymenoptera: Cynipidae: Cynipini are described from Panama and Costa Rica: Neuroterus elvisi sp. n., Neuroterus pulchrigalla sp. n., and Neuroterus glandiphilus sp. n. The new species are the first of the genus Neuroterus recorded from Central America and the Neotropical region. The new species induce galls on Quercus bumelioides Liebm. (Fagaceae, sect. Quercus, White Oaks. Additional evidence of the presence of other unidentified species of Neuroterus in the sampled area is presented. Diagnostic morphological characters, gall descriptions, distributions, host plant and other biological data of the new species are given and discussed. http://urn:lsid:zoobank.org:pub:48D0C1E1-1D0C-40D8-B890-FFC85AE7A213

  15. Is violence associated with increased risk behavior among MSM? Evidence from a population-based survey conducted across nine cities in Central America.

    Wheeler, Jennifer; Anfinson, Katherine; Valvert, Dennis; Lungo, Susana

    2014-01-01

    There is a dearth of research examining the linkages between violence and HIV risk behavior among men who have sex with men (MSM), including those who identify as transgender women (TW), particularly in Central America where violence is widespread. In this paper, we use population-based survey results to independently examine the correlations between physical, emotional and sexual violence and HIV risk behavior among MSM populations in five countries in Central America. As part of USAID's Combination Prevention for HIV program in Central America, PASMO conducted population based surveys using respondent-driven sampling (RDS) in nine cities in Guatemala, El Salvador, Nicaragua, Costa Rica, and Panama. Initial seeds were recruited using the following criteria: individuals who represented subgroups of MSM by self-identification (homosexual vs. heterosexual or bisexual vs. transgender), social economic strata, and by sex work practices. This study examines the association between violence and 1) HIV risk behaviors relevant to the study populations; 2) protective behaviors; and 3) reported STIs. Individualized RDS estimator weights for each outcome variable were calculated using RDSAT software, and logistic regression analysis was used to determine associations between different forms of violence and the outcome variables. MSM who experienced physical violence were more likely to be engaged in transactional sex (OR: 1.76 [1.42-2.18]), have multiple partners in the past 30 days (OR: 1.37 [1.09-1.71]), and have engaged in sex under the influence of alcohol or drugs (OR: 1.51 [1.24-1.83]). Both physical violence and psychological/verbal violence were also associated with reporting STI symptoms or diagnosis within the past 12 months (OR: 1.72 [1.34-2.21] and 1.80 [1.45-2.23]). The effects of violence on the outcomes were observed after controlling for other risk factors. Transgender women were 3.9 times more likely to report engaging in transactional sex. Respondents who

  16. Is violence associated with increased risk behavior among MSM? Evidence from a population-based survey conducted across nine cities in Central America

    Jennifer Wheeler

    2014-10-01

    Full Text Available Background/Objective: There is a dearth of research examining the linkages between violence and HIV risk behavior among men who have sex with men (MSM, including those who identify as transgender women (TW, particularly in Central America where violence is widespread. In this paper, we use population-based survey results to independently examine the correlations between physical, emotional and sexual violence and HIV risk behavior among MSM populations in five countries in Central America. Design: As part of USAID's Combination Prevention for HIV program in Central America, PASMO conducted population based surveys using respondent-driven sampling (RDS in nine cities in Guatemala, El Salvador, Nicaragua, Costa Rica, and Panama. Initial seeds were recruited using the following criteria: individuals who represented subgroups of MSM by self-identification (homosexual vs. heterosexual or bisexual vs. transgender, social economic strata, and by sex work practices. This study examines the association between violence and 1 HIV risk behaviors relevant to the study populations; 2 protective behaviors; and 3 reported STIs. Individualized RDS estimator weights for each outcome variable were calculated using RDSAT software, and logistic regression analysis was used to determine associations between different forms of violence and the outcome variables. Results: MSM who experienced physical violence were more likely to be engaged in transactional sex (OR: 1.76 [1.42–2.18], have multiple partners in the past 30 days (OR: 1.37 [1.09–1.71], and have engaged in sex under the influence of alcohol or drugs (OR: 1.51 [1.24–1.83]. Both physical violence and psychological/verbal violence were also associated with reporting STI symptoms or diagnosis within the past 12 months (OR: 1.72 [1.34–2.21] and 1.80 [1.45–2.23]. The effects of violence on the outcomes were observed after controlling for other risk factors. Transgender women were 3.9 times more likely

  17. Magmas with slab fluid and decompression melting signatures coexisting in the Gulf of Fonseca: Evidence from Isla El Tigre volcano (Honduras, Central America)

    Mattioli, Michele; Renzulli, Alberto; Agostini, Samuele; Lucidi, Roberto

    2016-01-01

    Isla El Tigre volcano is located in the Gulf of Fonseca (Honduras) along the Central America volcanic front, where a significant change in the strike of the volcanic chain is observed. The studied samples of this poorly investigated volcano are mainly subalkaline basic to intermediate lavas (basalts and basaltic andesites) and subordinate subalkaline/alkaline transitional basalts, both having the typical mineralogical and geochemical characteristics of arc volcanic rocks. On the basis of petrographic and geochemical features, two groups of rocks have been distinguished. Lavas from the main volcanic edifice are highly porphyritic and hy-qz normative, and have lower MgO contents ( 5 wt.%), are ol-hy normative and show lower HFSE depletions relative to LILE and LREE, with lower Ba/La, Ba/Nb and Zr/Nb ratios. This suggests that mantle-derived magmas were not produced by the same process throughout the activity of the volcano. The bulk rock geochemistry and 87Sr/86Sr (0.70373-0.70382), 143Nd/144Nd (0.51298-0.51301), 206Pb/204Pb (18.55-18.58), 207Pb/204Pb (15.54-15.56) and 208Pb/204Pb (38.23-38.26) isotopic data of Isla El Tigre compared with the other volcanoes of the Gulf of Fonseca and all available literature data for Central America suggests that this stratovolcano was mainly built by mantle-derived melts driven by slab-derived fluid-flux melting, while magmas erupted through its parasitic cones have a clear signature of decompression melting with minor slab contribution. The coexistence of these two different mantle melting generation processes is likely related to the complex geodynamic setting of the Gulf of Fonseca, where the volcanic front changes direction by ca. 30° and two fundamental tectonic structures of the Chortis continental block, mainly the N-S Honduras Depression and the NE-SW Guayape Fault Zone, cross each other.

  18. Insights into the ecology, genetics and distribution of Lucanus elaphus Fabricius (Coleoptera: Lucanidae), North America's giant stag beetle

    Michael D. Ulyshen; Louis G. Zachos; John O. Stireman; Thomas N. Sheehan; Ryan C. Garrick

    2017-01-01

    1. Little is known about the biology or conservation status of Lucanus elaphus Fabricius in North America despite well-documented declines of a related species, Lucanus cervus (L.), in Europe. This study provides information critical to developing conservation plans for L. elaphus...

  19. 4.4.5S: Genetic interactions of white pines and blister rust in western North America

    Bohun B. Kinloch Jr.

    1998-01-01

    A century since its introduction to North America from Europe, white pine blister rust has come to be recognized as one of the catastrophic plant disease epidemics in history. It has yet to stabilize, continuing to spread and intensify. The nine native white pine hosts comprise major timber producers, important watershed protectors, keystone ecological species, and the...

  20. Genetic characterization of Neotropical Jabiru Storks: Insights for conservation

    Lopes, I.F.; Haig, S.M.; Lama, S.N.D.

    2010-01-01

    Jabiru Stork (Jabiru mycteria is listed under Appendix I of CITES and considered threatened in Central America. The first population genetic analysis of Jabiru Storks was carried out using mitochondrial DNA (mtDNA) control region sequences (520 bp) and five heterologous microsatellite loci. Samples were collected from the field (N = 49) and museum skins (N = 22) in Central (mainly Belize, Nicaragua and Costa Rica) and South America (Colombia, Venezuela, Peru and Brazil). A decline of mtDNA diversity was observed in comparisons between past (N = 20) and present (N = 40) samples collected in Central America and northern South America. Similar levels of microsatellite loci diversity were observed among contemporary samples. Lower levels of mtDNA variability were observed in samples from Central America and northern South America when compared to the Brazilian Pantanal region. Significant levels of genetic differentiation were found between contemporary locations sampled, whereas non-significant results were observed for historic samples. The non-geographic association of haplotypes observed at the cladograms and the recent divergence times estimated between locations are indicative of an evolutionary history of a large population size with limited population structure. Reconnection of populations via increased gene flow, particularly in Central America, is recommended if genetic structure and status are to be restored.

  1. Genetic Structuration, Demography and Evolutionary History of Mycobacterium tuberculosis LAM9 Sublineage in the Americas as Two Distinct Subpopulations Revealed by Bayesian Analyses

    Reynaud, Yann; Millet, Julie; Rastogi, Nalin

    2015-01-01

    Tuberculosis (TB) remains broadly present in the Americas despite intense global efforts for its control and elimination. Starting from a large dataset comprising spoligotyping (n = 21183 isolates) and 12-loci MIRU-VNTRs data (n = 4022 isolates) from a total of 31 countries of the Americas (data extracted from the SITVIT2 database), this study aimed to get an overview of lineages circulating in the Americas. A total of 17119 (80.8%) strains belonged to the Euro-American lineage 4, among which the most predominant genotypic family belonged to the Latin American and Mediterranean (LAM) lineage (n = 6386, 30.1% of strains). By combining classical phylogenetic analyses and Bayesian approaches, this study revealed for the first time a clear genetic structuration of LAM9 sublineage into two subpopulations named LAM9C1 and LAM9C2, with distinct genetic characteristics. LAM9C1 was predominant in Chile, Colombia and USA, while LAM9C2 was predominant in Brazil, Dominican Republic, Guadeloupe and French Guiana. Globally, LAM9C2 was characterized by higher allelic richness as compared to LAM9C1 isolates. Moreover, LAM9C2 sublineage appeared to expand close to twenty times more than LAM9C1 and showed older traces of expansion. Interestingly, a significant proportion of LAM9C2 isolates presented typical signature of ancestral LAM-RDRio MIRU-VNTR type (224226153321). Further studies based on Whole Genome Sequencing of LAM strains will provide the needed resolution to decipher the biogeographical structure and evolutionary history of this successful family. PMID:26517715

  2. Genetic relatedness and molecular characterization of multidrug resistant Acinetobacter baumannii isolated in central Ohio, USA

    Tadesse Daniel

    2009-06-01

    Full Text Available Abstract Background Over the last decade, nosocomial infections due to Acinetobacter baumannii have been described with an increasing trend towards multidrug resistance, mostly in intensive care units. The aim of the present study was to determine the clonal relatedness of clinical isolates and to elucidate the genetic basis of imipenem resistance. Methods A. baumannii isolates (n = 83 originated from two hospital settings in central Ohio were used in this study. Pulsed-field gel electrophoresis genotyping and antimicrobial susceptibility testing for clinically relevant antimicrobials were performed. Resistance determinants were characterized by using different phenotypic (accumulation assay for efflux and genotypic (PCR, DNA sequencing, plasmid analysis and electroporation approaches. Results The isolates were predominantly multidrug resistant (>79.5% and comprised of thirteen unique pulsotypes, with genotype VII circulating in both hospitals. The presence of blaOXA-23 in 13% (11/83 and ISAba1 linked blaOXA-66 in 79.5% (66/83 of clinical isolates was associated with high level imipenem resistance. In this set of OXA producing isolates, multidrug resistance was bestowed by blaADC-25, class 1 integron-borne aminoglycoside modifying enzymes, presence of sense mutations in gyrA/parC and involvement of active efflux (with evidence for the presence of adeB efflux gene. Conclusion This study underscores the major role of carbapenem-hydrolyzing class D β-lactamases, and in particular the acquired OXA-23, in the dissemination of imipenem-resistant A. baumannii. The co-occurrence of additional resistance determinant could also be a significant threat.

  3. Management training in global health education: a Health Innovation Fellowship training program to bring healthcare to low-income communities in Central America.

    Prado, Andrea M; Pearson, Andy A; Bertelsen, Nathan S

    2018-01-01

    Interprofessional education is increasingly recognized as essential for health education worldwide. Although effective management, innovation, and entrepreneurship are necessary to improve health systems, business schools have been underrepresented in global health education. Central America needs more health professionals trained in health management and innovation to respond to health disparities, especially in rural communities. This paper explores the impact of the Health Innovation Fellowship (HIF), a new training program for practicing health professionals offered jointly by the Central American Healthcare Initiative and INCAE Business School, Costa Rica. Launched in 2014, HIF's goal is to create a network of highly trained interdisciplinary health professionals in competencies to improve health of Central American communities through better health management. The program's fellows carried out innovative healthcare projects in their local regions. The first three annual cohorts (total of 43 fellows) represented all health-related professions and sectors (private, public, and civil society) from six Central American countries. All fellows attended four 1-week, on-site modular training sessions, received ongoing mentorship, and stayed connected through formal and informal networks and webinars through which they exchange knowledge and support each other. CAHI stakeholders supported HIF financially. Impact evaluation of the three-year pilot training program is positive: fellows improved their health management skills and more than 50% of the projects found either financial or political support for their implementation. HIF's strengths include that both program leaders and trainees come from the Global South, and that HIF offers a platform to collaborate with partners in the Global North. By focusing on promoting innovation and management at a top business school in the region, HIF constitutes a novel capacity-building effort within global health education. HIF

  4. Channel Response To Global Warming In East-Central North America: Using The Hypsithermal As A Guide

    Springer, G. S.; Rowe, H. D.; Cocina, F. G.

    2006-12-01

    Average global temperatures during the mid-Holocene Hypsithermal Interval were as much as 2° C warmer than present. The Hypsithermal is recorded in sediments of a West Virginia, USA cave as less negative values of &δ13C. The sediments were deposited by floodwaters of the adjacent Greenbrier River. Bat bones and other evidence of subaerial exposure between floods are found throughout silt-dominated sediments, except during the Hypsithermal. Sediments of the Hypsithermal are primarily clays containing occasional marine fossils and insoluble particles liberated from the host limestone during a period of sustained backflooding. Blockage of three widely separated outlets is required for backflooding, which would have occurred if the riverbed aggraded during the Hypsithermal. Warm, dry periods, such as Hypsithermal, are known to produce aggradation of channel beds. The riverbed may have risen as much as 4 m in this case, which is the maximum height of clay above the present bedrock-floored riverbed. Global warming may return the Earth to Hypsithermal conditions and lead to renewed channel infilling. Aggradation of the magnitude inferred here would leave regional floodplains and towns susceptible to frequent flooding. Societal and economic costs associated with living in close association with streams and rivers would significantly increase and channel infrastructure would be disrupted. Global warming has the potential to fundamentally alter society's relationship to the physical properties of river channels in Eastern North America.

  5. Distribution and Genetic Structure of Fucus distichus Linnaeus 1953 (formerly F. gardneri within Central San Francisco Bay

    Stephen G. Whitaker

    2017-09-01

    Full Text Available doi: https://doi.org/10.15447/sfews.2017v15iss3art4Fucus distichus, a rockweed common to the mid-intertidal shoreline within the San Francisco Estuary (previously known as F. gardneri, was injured during the Cosco Busan oil spill in November 2007 and subsequent clean-up actions. Restoration planning activities are underway to help recover F. distichus at sites within central San Francisco Bay where damage occurred. As a first step, we conducted shoreline surveys during the summers of 2012–2013 to map the occurrence of this rockweed. Of the 151.73 km of rocky shoreline within the central bay, F. distichus covered 32.16 km of shoreline. The alga generally occurred in narrow bands but formed expansive beds at locations with natural, flat bedrock benches. We also observed F. distichus on artificial substrata such as seawalls and riprap, but not on pilings. Samples of F. distichus from 11 sites throughout the central / east San Francisco Bay were genetically analyzed (microsatellite genotyping. The populations analyzed (1 had low genetic diversity, (2 the frequency of homozygotes was higher than expected (suggesting high inbreeding, and (3 also displayed geographic population structure, in part driven by very small differences in the midst of extremely low within-population genetic diversity. However, these genetic data do not raise concerns for restoration methods in terms of choosing donor populations and mixing F. distichus from different sites within the central bay. The choice of donor populations should be based on practical criteria for effective restoration; individuals will nonetheless be taken from locations as nearby to donor sites as possible. Various locations throughout the central San Francisco Bay are composed of cobble or small riprap that are populated with F. distichus, which could provide efficient means of translocating rockweed for future restoration activities.

  6. Paleoseismic analysis of the San Vicente segment of the El Salvador Fault Zone, El Salvador, Central America

    Canora Catalán, Carolina; Villamor Pérez, María Pilar; Martínez Díaz, José J.; Berryman, K.R.; Álvarez Gómez, José Antonio; Capote del Villar, Ramón; Hernández, Walter

    2012-01-01

    The El Salvador earthquake of February 13th 2001 (Mw 6.6) was associated with the tectonic rupture of the El Salvador Fault Zone. Paleoseismic studies of the El Salvador Fault Zone undertaken after this earthquake provide a basis for examining the longer history of surface rupturing earthquakes on the fault. Trenching at five sites along the San Vicente segment, a 21km-long and up to 2km-wide central section of the El Salvador Fault Zone, shows that surface fault rupture has occurred at least...

  7. Comparative Vector Bionomics and Morphometrics of Two Genetically Distinct Field Populations of Anopheles darlingi Root from Belize, Central America and Zungarococha, Peru, South America

    2014-01-31

    zone River edge in mats of water hyacinth and water Aseli Kamp fern and seasonally-flooded forest between grass stems and floatil’!.9_ debris...Belize 100% 90% ’O 80% ~ ..! 0 70% <> • ~ 60% :; 13Human CT • 0 E 50% :! •Pig .e - 40% 0 CD Cll s 30% c CD I:! CD II.. 20% An. darlingi

  8. South America Monsoon variability on millennial to multi-centennial time scale during the Holocene in central eastern Brazil

    Strikis, N. M.; Cruz, F. W.; Cheng, H.; Karmann, I.; Vuille, M.; Edwards, R.; Wang, X.; Paula, M. S.; Novello, V. F.; Auler, A.

    2011-12-01

    A paleoprecipitation reconstruction based on high resolution and well-dated speleothem oxygen isotope records shows that the monsoon precipitation over central eastern Brazil underwent to strong variations on millennial to multi-centennial time-scales during the Holocene. This new record indicates that abrupt events of increase in monsoon precipitation are correlated to Bond events 6, 5 and 4 and also with 8.2 ky event during the early and mid-Holocene, with a mean amplitude of 1.5 % (PDB). The pacing and structure of such events are general consistent with variations in solar activity suggested by atmospheric Δ14 C records. In the late-Holocene, abrupt events of increase in monsoon precipitation peaking at 3.2, 2.7 and 2.3 ky B.P. are approximately synchronous with periods of low solar minima. In this regard, the most prominent event occurred during the late Holocene occurred at ~2.7 ky B.P. In addition, these positive anomalies of the precipitation recorded in central eastern Brazil are also in good agreement with variations in Titicaca lake level. The good correspondence between the speleothem and marine records imply that the variations in the north Atlantic sea surface temperature is the main forcing for abrupt millennial to multi-centennial precipitations variation within the region under influence of South American Monsoon.

  9. Biochemical Systematics and Population Genetic Structure of Anopheles Pseudopunctipennis, Vector of Malaria in Central and South America

    1995-01-01

    Biosystematics Unit, Department of Entomology, Walter Reed Army Institute of Research, Washington, District of Columbia; Laboratorio de Entomologia ...Entomology, Walter Reed Army Institute of Research, Washington, DC 20307-5 100. Ildefonso Fernandez-Sa- las, Laboratorio de Entomologia Medica

  10. GPS-derived coupling estimates for the Central America subduction zone and volcanic arc faults: El Salvador, Honduras and Nicaragua

    Correa-Mora, F.; DeMets, C.; Alvarado, D.; Turner, H. L.; Mattioli, G.; Hernandez, D.; Pullinger, C.; Rodriguez, M.; Tenorio, C.

    2009-12-01

    We invert GPS velocities from 32 sites in El Salvador, Honduras and Nicaragua to estimate the rate of long-term forearc motion and distributions of interseismic coupling across the Middle America subduction zone offshore from these countries and faults in the Salvadoran and Nicaraguan volcanic arcs. A 3-D finite element model is used to approximate the geometries of the subduction interface and strike-slip faults in the volcanic arc and determine the elastic response to coupling across these faults. The GPS velocities are best fit by a model in which the forearc moves 14-16 mmyr-1 and has coupling of 85-100 per cent across faults in the volcanic arc, in agreement with the high level of historic and recent earthquake activity in the volcanic arc. Our velocity inversion indicates that coupling across the potentially seismogenic areas of the subduction interface is remarkably weak, averaging no more than 3 per cent of the plate convergence rate and with only two poorly resolved patches where coupling might be higher along the 550-km-long segment we modelled. Our geodetic evidence for weak subduction coupling disagrees with a seismically derived coupling estimate of 60 +/- 10 per cent from a published analysis of earthquake damage back to 1690, but agrees with three other seismologic studies that infer weak subduction coupling from 20th century earthquakes. Most large historical earthquakes offshore from El Salvador and western Nicaragua may therefore have been intraslab normal faulting events similar to the Mw 7.3 1982 and Mw 7.7 2001 earthquakes offshore from El Salvador. Alternatively, the degree of coupling might vary with time. The evidence for weak coupling indirectly supports a recently published hypothesis that much of the Middle American forearc is escaping to the west or northwest away from the Cocos Ridge collision zone in Costa Rica. Such a hypothesis is particularly attractive for El Salvador, where there is little or no convergence obliquity to drive the

  11. Working conditions and health in Central America: a survey of 12,024 workers in six countries.

    Benavides, Fernando G; Wesseling, Catharina; Delclos, George L; Felknor, Sarah; Pinilla, Javier; Rodrigo, Fernando

    2014-07-01

    To describe the survey methodology and initial general findings of the first Central American Survey of Working Conditions and Health. A representative sample of 12,024 workers was interviewed at home in Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua and Panama. Questionnaire items addressed worker demographics, employment conditions, occupational risk factors and self-perceived health. Overall, self-employment (37%) is the most frequent type of employment, 8% of employees lack a work contract and 74% of the workforce is not covered by social security. These percentages are higher in Guatemala, Honduras and El Salvador, and lower in Costa Rica, Panama and Nicaragua. A third of the workforce works more than 48 h per week, regardless of gender; this is similar across countries. Women and men report frequent or usual exposures to high ambient temperature (16% and 25%, respectively), dangerous tools and machinery (10%, 24%), work on slippery surfaces (10%, 23%), breathing chemicals (12.1%, 18%), handling toxic substances (5%, 12.1%), heavy loads (6%, 20%) and repetitive movements (43%, 49%). Two-thirds of the workforce perceive their health as being good or very good, and slightly more than half reports having good mental health. The survey offers, for the first time, comparable data on the work and health status of workers in the formal and informal economy in the six Spanish-speaking Central American countries, based on representative national samples. This provides a benchmark for future monitoring of employment and working conditions across countries. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  12. Radical, reformist and aborted liberalism: origins of national regimes in Central America Liberalismo radical, reformista y frustrado: orígenes de los regímenes nacionales en América central

    James MAHONEY

    2011-06-01

    Full Text Available During the twentieth century, the countries of Central America were characterized by remarkably different political regimes: military-authoritarianism in Guatemala and El Salvador, progressive democracy in Costa Rica and traditional-authoritarianism in Honduras and Nicaragua. This article explains these contrasting regime outcomes by exploring the agrarian and state-building reforms pursued by political leaders during the nineteenth– and early twentieth century liberal reform period. Based on differences in the transformation of state and class structures, three types of liberalism are identified: radical liberalism in Guatemala and El Salvador, reformist liberalism in Costa Rica and aborted liberalism in Honduras and Nicaragua. It is argued that these types of liberalism set the Central American countries on contrasting paths of political development, culminating in diverse regime outcomes.Durante el siglo XX, los países de América Central se caracterizaron por tener regímenes políticos muy diferentes: el autoritarismo militar en Guatemala y El Salvador; la democracia progresista en Costa Rica y el autoritarismo tradicional en Honduras y Nicaragua. Este artículo explica los resultados de estos distintos regímenes mediante la exploración de las reformas agrarias y de la construcción del Estado llevadas a cabo por los líderes políticos durante el siglo XIX y principios del periodo de reformas liberales del siglo XX. Basándose en las diferencias de la transformación del Estado y de las estructuras de clases, se pueden identificar tres tipos de liberalismo: liberalismo radical en Guatemala y El Salvador; liberalismo reformista en Costa Rica y liberalismo frustrado en Honduras y Nicaragua. Se argumenta que estos tipos de liberalismo condujeron a los países de América Central a caminos contrarios al desarrollo político, culminando así en regímenes con resultados diversos.

  13. Controls on reef development and the terrigenous-carbonate interface on a shallow shelf, Nicaragua (Central America)

    Roberts, H. H.; Murray, S. P.

    1983-06-01

    Marine geology and physical oceanographic data collected during two field projects (˜4 months) on the Caribbean shelf of Nicaragua indicate a surprising dominance of carbonate deposition and reef growth on a shelf that is receiving an abnormally large volume of terrigenous sediments. High rainfall rates (˜400 500 cm/year), coupled with a warm tropical climate, encourage rapid denudation of the country's central volcanic highland and transport of large volumes of terrigenous sediment and fresh water to the coast. Estimates suggest that three times more fresh water and fifteen times more sediment are introduced per unit length of coastline than on the east coast of the United States. Distribution of the terrigenous facies, development of carbonate sediment suites, and the location and quality of viable reefs are strongly controlled by the dynamic interaction near the coasts of highly turbid fresh to brackish water effluents from thirteen rivers with clear marine waters of the shelf. Oceanic water from the central Caribbean drift current intersects the shelf and moves slowely in a dominant northwest direction toward the Yucatan Channel. A sluggish secondary gyre moves to the south toward Costa Rica. In contrast, the turbid coastal water is deflected to the south in response to density gradients, surface water slopes, and momentum supplied by the steady northeast trade winds. A distinct two-layered flow is commonly present in the sediment-rich coastal boundary zone, which is typically 10 20 km wide. The low-salinity upper layer is frictionally uncoupled from the ambient shelf water and therefore can expand out of the normally coherent coastal boundary zone during periods of abnormal flooding or times when instability is introduced into the northeast trades. Reef distribution, abruptness of the terrigenous-carbonate interface, and general shelf morphology reflect the long-term dynamic structure of the shelf waters. A smooth-bottomed ramp of siliciclastic sands to

  14. A pollen-based reconstruction of summer temperature in central North America and implications for circulation patterns during medieval times

    Wahl, Eugene R.; Diaz, Henry F.; Ohlwein, Christian

    2012-03-01

    We present a reconstruction of mean summer temperature for the northern Midwest of the USA based on lacustrine pollen records from three different lakes in Wisconsin. The results suggest a relatively warm period during the earlier part of the record (~ 1200-1500 CE) followed by a cooler Little Ice Age (~ 1500-1900) and a subsequent warming to modern conditions. The reconstructed modern summer mean temperature is in good agreement with observations, and the decades of the 1930s to 1950s appear to be the warmest such period in the proxy record (through 1974). Analyses of circulation features associated with the warmest summers in the recent climate record suggest a prevalence of continental ridging accompanied by generally dry conditions during these warm summers in the Midwest. Drought reconstruction using the Palmer Drought Severity Index (PDSI) and tree-ring records as predictors also yield relatively dry conditions in medieval times for the central US. As reported in a number of recent studies, possible forcing mechanisms include La Niña-like conditions in the equatorial Pacific and warmer than average waters in the tropical Indo-western Pacific Ocean possibly coupled to a positive mode of the AMO/NAO North Atlantic circulation pattern.

  15. Regional International Courts in Search of Relevance - Adjudicating Politically Sensitive Disputes in Central America and the Caribbean

    Caserta, Salvatore

    2017-01-01

    The Central American and of the Caribbean Courts of Justice (CACJ and CCJ) are hybrid judicial institutions. While their Member States chiefly envisaged them as EU-style regional economic courts, they have explored the whole extension of their formally delegated functions and have developed pecul...... sensitive issues becomes less surprising, and – the article argues – it constitutes part of a strategy of the judges to legitimize the two Courts vis-à-vis their peculiar institutional, political, and social environments....... peculiar expertise in matters relating to freedom of movement, human and fundamental rights, and mega-politics. The article explains how two ICs seemingly established to build common markets have come to rule on high-stakes political disputes, which, ostensibly, have little to do with regional economic...... integration. The article posits that the scholarship on delegation to ICs is only partially able to provide an answer to this question. It, hence, suggests an alternative theoretical framework by relying on transnational field theory and reflexive sociology. The article demonstrates that, despite the rhetoric...

  16. Estimating the reproductive number, total outbreak size, and reporting rates for Zika epidemics in South and Central America

    Deborah P. Shutt

    2017-12-01

    Full Text Available As South and Central American countries prepare for increased birth defects from Zika virus outbreaks and plan for mitigation strategies to minimize ongoing and future outbreaks, understanding important characteristics of Zika outbreaks and how they vary across regions is a challenging and important problem. We developed a mathematical model for the 2015/2016 Zika virus outbreak dynamics in Colombia, El Salvador, and Suriname. We fit the model to publicly available data provided by the Pan American Health Organization, using Approximate Bayesian Computation to estimate parameter distributions and provide uncertainty quantification. The model indicated that a country-level analysis was not appropriate for Colombia. We then estimated the basic reproduction number to range between 4 and 6 for El Salvador and Suriname with a median of 4.3 and 5.3, respectively. We estimated the reporting rate to be around 16% in El Salvador and 18% in Suriname with estimated total outbreak sizes of 73,395 and 21,647 people, respectively. The uncertainty in parameter estimates highlights a need for research and data collection that will better constrain parameter ranges.

  17. Zoonotic and infectious disease surveillance in Central America: Honduran feral cats positive for toxoplasma, trypanosoma, leishmania, rickettsia, and Lyme disease.

    McCown, Michael; Grzeszak, Benjamin

    2010-01-01

    A recent zoonotic and infectious disease field surveillance study in Honduras resulted in the discovery of Toxoplasma, Trypanosoma, Leishmania, Rickettsia, and Lyme disease with statistically high prevalence rates in a group of feral cats. All five diseases--Toxoplasmosis, Trypanosomiasis, Leishmaniasis, Rickettsiosis, and Lyme disease--were confirmed in this group of cats having close contact to local civilians and U.S. personnel. These diseases are infectious to other animals and are known to infect humans as well. In the austere Central and South American sites that Special Operations Forces (SOF) medics are deployed, the living conditions and close quarters are prime environments for the potential spread of infectious and zoonotic disease. This study?s findings, as with previous veterinary disease surveillance studies, emphasize the critical need for continual and aggressive surveillance for zoonotic and infectious disease present within animals in specific areas of operation (AO). The importance to SOF is that a variety of animals may be sentinels, hosts, or direct transmitters of disease to civilians and service members. These studies are value-added tools to the U.S. military, specifically to a deploying or already deployed unit. The SOF medic must ensure that this value-added asset is utilized and that the findings are applied to assure Operational Detachment-Alpha (SFOD-A) health and, on a bigger scale, U.S. military force health protection and local civilian health. © 2010.

  18. Estimating the reproductive number, total outbreak size, and reporting rates for Zika epidemics in South and Central America.

    Shutt, Deborah P; Manore, Carrie A; Pankavich, Stephen; Porter, Aaron T; Del Valle, Sara Y

    2017-12-01

    As South and Central American countries prepare for increased birth defects from Zika virus outbreaks and plan for mitigation strategies to minimize ongoing and future outbreaks, understanding important characteristics of Zika outbreaks and how they vary across regions is a challenging and important problem. We developed a mathematical model for the 2015/2016 Zika virus outbreak dynamics in Colombia, El Salvador, and Suriname. We fit the model to publicly available data provided by the Pan American Health Organization, using Approximate Bayesian Computation to estimate parameter distributions and provide uncertainty quantification. The model indicated that a country-level analysis was not appropriate for Colombia. We then estimated the basic reproduction number to range between 4 and 6 for El Salvador and Suriname with a median of 4.3 and 5.3, respectively. We estimated the reporting rate to be around 16% in El Salvador and 18% in Suriname with estimated total outbreak sizes of 73,395 and 21,647 people, respectively. The uncertainty in parameter estimates highlights a need for research and data collection that will better constrain parameter ranges. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  19. 300 years of hydrological records and societal responses to droughts and floods on the Pacific coast of Central America

    A. Guevara-Murua

    2018-02-01

    Full Text Available The management of hydrological extremes and impacts on society is inadequately understood because of the combination of short-term hydrological records, an equally short-term assessment of societal responses and the complex multi-directional relationships between the two over longer timescales. Rainfall seasonality and inter-annual variability on the Pacific coast of Central America is high due to the passage of the Inter Tropical Convergence Zone (ITCZ and the El Niño–Southern Oscillation (ENSO. Here we reconstruct hydrological variability and demonstrate the potential for assessing societal impacts by drawing on documentary sources from the cities of Santiago de Guatemala (now Antigua Guatemala and Guatemala de la Asunción (now Guatemala City over the period from 1640 to 1945. City and municipal council meetings provide a rich source of information dating back to the beginning of Spanish colonisation in the 16th century. We use almost continuous sources from 1640 AD onwards, including > 190 volumes of Actas de Cabildo and Actas Municipales (minutes of meetings of the city and municipal councils held by the Archivo Histórico de la Municipalidad de Antigua Guatemala (AHMAG and the Archivo General de Centro América (AGCA in Guatemala City. For this 305-year period (with the exception of a total of 11 years during which the books were either missing or damaged, information relating to Catholic rogation ceremonies and reports of flooding events and crop shortages were used to classify the annual rainy season (May to October on a five-point scale from very wet to very dry. In total, 12 years of very wet conditions, 25 years of wetter than usual conditions, 34 years of drier conditions and 21 years of very dry conditions were recorded. An extended drier period from the 1640s to the 1740s was identified and two shorter periods (the 1820s and the 1840s were dominated by dry conditions. Wetter conditions dominated the 1760s–1810s and

  20. Efficacy and safety of etanercept in patients from Latin America, Central Europe and Asia with early non-radiographic axial spondyloarthritis.

    Wei, James Cheng-Chung; Tsai, Wen-Chan; Citera, Gustavo; Kotak, Sameer; Llamado, Lyndon

    2016-11-11

    To evaluate etanercept in patients from Latin America, Central/Eastern Europe, and Asia with non-radiographic axial spondyloarthritis (nr-axSpA). A subset analysis was performed on nr-axSpA patients from Argentina, Colombia, the Czech Republic, Hungary, Russia and Taiwan who were enrolled in EMBARK (NCT01258738). Patients received either etanercept 50 mg or placebo once weekly. The primary endpoint was proportion of patients achieving 40% improvement from baseline based on Assessment of SpondyloArthritis International Society (ASAS) criteria. Secondary endpoints included other efficacy assessments, health-related quality of life (HRQoL) and safety. Of the 117 patients in this subset, 59 were treated with etanercept and 58 received placebo. At week 12, numerically greater improvements from baseline were observed for all efficacy endpoints in etanercept-treated patients compared with those receiving placebo. Statistically significant differences between the two treatment groups were observed for proportion of patients achieving ASAS40 (P = 0.0413, at week 8), ASAS5/6 (P = 0.0126), Ankylosing Spondylitis Disease Activity Score - C-reactive protein (CRP) inactive disease (P = 0.0093), Spondyloarthritis Research Consortium of Canada magnetic resonance imaging of sacroiliac joint scores (P = 0.0014), high-sensitivity CRP (P=0.032), and erythrocyte sedimentation rate (P = 0.0082). Statistically significant improvements in the etanercept-treated group compared with placebo group were observed for nocturnal back pain (P = 0.040), total back pain (P = 0.025), physician global assessment of disease (P = 0.023), and Work Productivity and Activity Impairment Questionnaire percent impairment while working (P = 0.047). Adverse events were similar between the two treatment groups. In this subset of patients with nr-axSpA from Latin America, Central/Eastern Europe, and Asia, treatment with etanercept, compared with placebo, resulted in improved disease symptoms and patient HRQo

  1. Evidence and future scenarios of a low-carbon energy transition in Central America: a case study in Nicaragua

    Barido, Diego Ponce de Leon; Johnston, Josiah; Moncada, Maria V.; Callaway, Duncan; Kammen, Daniel M.

    2015-10-01

    The global carbon emissions budget over the next decades depends critically on the choices made by fast-growing emerging economies. Few studies exist, however, that develop country-specific energy system integration insights that can inform emerging economies in this decision-making process. High spatial- and temporal-resolution power system planning is central to evaluating decarbonization scenarios, but obtaining the required data and models can be cost prohibitive, especially for researchers in low, lower-middle income economies. Here, we use Nicaragua as a case study to highlight the importance of high-resolution open access data and modeling platforms to evaluate fuel-switching strategies and their resulting cost of power under realistic technology, policy, and cost scenarios (2014-2030). Our results suggest that Nicaragua could cost-effectively achieve a low-carbon grid (≥80%, based on non-large hydro renewable energy generation) by 2030 while also pursuing multiple development objectives. Regional cooperation (balancing) enables the highest wind and solar generation (18% and 3% by 2030, respectively), at the least cost (US127 MWh-1). Potentially risky resources (geothermal and hydropower) raise system costs but do not significantly hinder decarbonization. Oil price sensitivity scenarios suggest renewable energy to be a more cost-effective long-term investment than fuel oil, even under the assumption of prevailing cheap oil prices. Nicaragua’s options illustrate the opportunities and challenges of power system decarbonization for emerging economies, and the key role that open access data and modeling platforms can play in helping develop low-carbon transition pathways.

  2. Climate oscillations, glacial refugia, and dispersal ability: factors influencing the genetic structure of the least salmonfly, Pteronarcella badia (Plecoptera), in Western North America.

    Sproul, John S; Houston, Derek D; Nelson, C Riley; Evans, R Paul; Crandall, Keith A; Shiozawa, Dennis K

    2015-12-12

    Phylogeographic studies of aquatic insects provide valuable insights into mechanisms that shape the genetic structure of communities, yet studies that include broad geographic areas are uncommon for this group. We conducted a broad scale phylogeographic analysis of the least salmonfly Pteronarcella badia (Plecoptera) across western North America. We tested hypotheses related to mode of dispersal and the influence of historic climate oscillations on population genetic structure. In order to generate a larger mitochondrial data set, we used 454 sequencing to reconstruct the complete mitochondrial genome in the early stages of the project. Our analysis revealed high levels of population structure with several deeply divergent clades present across the sample area. Evidence from five mitochondrial genes and one nuclear locus identified a potentially cryptic lineage in the Pacific Northwest. Gene flow estimates and geographic clade distributions suggest that overland flight during the winged adult stage is an important dispersal mechanism for this taxon. We found evidence of multiple glacial refugia across the species distribution and signs of secondary contact within and among major clades. This study provides a basis for future studies of aquatic insect phylogeography at the inter-basin scale in western North America. Our findings add to an understanding of the role of historical climate isolations in shaping assemblages of aquatic insects in this region. We identified several geographic areas that may have historical importance for other aquatic organisms with similar distributions and dispersal strategies as P. badia. This work adds to the ever-growing list of studies that highlight the potential of next-generation DNA sequencing in a phylogenetic context to improve molecular data sets from understudied groups.

  3. Population genetic structure in natural and reintroduced beaver (Castor fiber populations in Central Europe

    Kautenburger, R.

    2008-12-01

    Full Text Available Castor fiber Linnaeus, 1758 is the only indigenous species of the genus Castor in Europe and Asia. Due to extensive hunting until the beginning of the 20th century, the distribution of the formerly widespread Eurasian beaver was dramatically reduced. Only a few populations remained and these were in isolated locations, such as the region of the German Elbe River. The loss of genetic diversity in small or captive populations throughgenetic drift and inbreeding is a severe conservation problem. However, the reintroduction of beaver populations from several regions in Europe has shown high viability and populations today are growing fast. In the present study we analysed the population genetic structure of a natural and two reintroduced beaver populations in Germany and Austria. Furthermore, we studied the genetic differentiation between two beaver species, C. fiber and the American beaver (C. canadensis, using RAPD (Random Amplified Polymorphic DNA as a genetic marker. The reintroduced beaver populations of different origins and the autochthonous population of the Elbe River showed a similar low genetic heterogeneity. There was an overall high genetic similarity in the species C. fiber, and no evidence was found for a clear subspecific structure in the populations studied.

  4. A new endemic focus of Chagas disease in the northern region of Veraguas Province, Western Half Panama, Central America.

    Azael Saldaña

    Full Text Available BACKGROUND: Chagas disease was originally reported in Panama in 1931. Currently, the best knowledge of this zoonosis is restricted to studies done in historically endemic regions. However, little is known about the distribution and epidemiology of Chagas disease in other rural areas of the country. METHODS AND FINDINGS: A cross-sectional descriptive study was carried out between May 2005 - July 2008 in four rural communities of the Santa Fe District, Veraguas Province. The study included an entomologic search to collect triatomines, bloodmeal type identification and infection rate with trypanosomes in collected vectors using a dot- blot and PCR analysis, genotyping of circulating Trypanosoma cruzi (mini-exon gene PCR analysis and the detection of chagasic antibodies among inhabitants. The vector Rhodnius pallescens was more frequently found in La Culaca and El Pantano communities (788 specimens, where it was a sporadic household visitor. These triatomines presented darker coloration and larger sizescompared with typical specimens collected in Central Panama. Triatoma dimidiata was more common in Sabaneta de El Macho (162 specimens. In one small sub-region (El Macho, 60% of the houses were colonized by this vector. Of the examined R. pallescens, 54.7.0% (88/161 had fed on Didelphis marsupialis, and 24.6% (34/138 of T. dimidiata specimens collected inside houses were positive for human blood. R. pallescens presented an infection index with T. cruzi of 17.7% (24/136, with T. rangeli of 12.5% (17/136 and 50.7% (69/136 were mixed infections. In 117 T. dimidiata domestic specimens the infection index with T. cruzi was 21.4%. Lineage I of T. cruzi was confirmed circulating in these vectors. A T. cruzi infection seroprevalence of 2.3% (24/1,056 was found in this population. CONCLUSIONS: This is the first report of Chagas disease endemicity in Santa Fe District, and it should be considered a neglected public health problem in this area of Panama.

  5. Soil bioengineering measures for disaster mitigation and environmental restoration in Central America: authochtonal cuttings suitability and economic efficiency

    Petrone, A.; Preti, F.

    2009-04-01

    The use of Soil Bio-Engineering techniques in Developing countries is a relevant issue for Disaster mitigation, environmental restoration and poverty reduction. Research on authochtonal plants suitable for this kind of works and on economic efficiency is essential for the divulgation of this Discipline. The present paper is focused on this two issues related to the realization of various typologies of Soil Bio-engineering works in the Humid tropic of Nicaragua. In the area of Río Blanco, located in the Department of Matagalpa, Soil bio-engineering installations were built in several sites. The particular structures built were: drainages with live fascine mattress, a live palisade, a vegetated live crib wall for riverbank protection, a vegetative covering made of a metallic net and biotextile coupled with a live palisade made of bamboo. In order to evaluate the suitability of the various plants used in the works, monitorings were performed, one in the live palisade alongside an unpaved road and the other on the live crib wall along a riverbank, collecting survival rate and morphological parameters data. Concerning the economic efficiency we proceed to a financial analysis of the works and once the unit price was obtained, we converted the amount in EPP Dollars (Equal Purchasing Power) in order to compare the Nicaraguan context with the Italian one. Among the used species we found that Madero negro (Gliricidia sepium) and Roble macuelizo (Tabebuia rosea) are adequate for Soil-bioengineering measure on slopes while Helequeme (Erythrina fusca) reported a successful behaviour only in the crib wall for riverbank protection. In the comparison of the costs in Nicaragua and in Italy, the unit price reduction for the central American country ranges between 1.5 times (for the vegetative covering) and almost 4 times (for the fascine mattress) if it's used the EPP dollar exchange rate. Thus, a conclusion can be reached with regard to hydrological-risk mitigating actions

  6. Anomalous Diffuse CO2 Emission Changes at San Vicente Volcano Related to Earthquakes in El Salvador, Central America

    Salazar, J.; Hernandez, P.; Perez, N.; Barahona, F.; Olmos, R.; Cartagena, R.; Soriano, T.; Notsu, K.; Lopez, D.

    2001-12-01

    San Vicente or Chichontepeque (2,180 m a.s.l.) is a composite andesitic volcano located 50 Km east of San Salvador. Its paired edifice rises from the so-called Central Graben, an extensional structure parallel to the Pacific coast, and has been inactive for the last 3000 yrs. Fumaroles (98.2°C ) and hot spring waters are present along radial faults at two localities on the northern slope of the volcano (Aguas Agrias and El Infiernillo). CO2 is the most abundant component in the dry gas (>90%) and its mean isotopic composition (δ 13C(CO2)=-2.11 ‰ and 3He/4He of 6.9 Ra) suggests a magmatic origin for the CO2. These manifestations are supposed to be linked to a 1,200 m depth 250°C reservoir with a CO2 partial pressure of 14 bar extended beneath the volcano (Aiuppa et al., 1997). In February 13, 2001, a 6.6 magnitude earthquake with epicenter about 20 Km W of San Vicente damaged and destroyed many towns and villages in the north area of the volcano causing some deceases. In addition, two seismic swarms were recorded beneath the northeastern flank of the volcano in April and May 2001. Searching for any link between the actual seismic activity and changes in the diffuse CO2 degassing at San Vicente, an NDIR instrument for continuos monitoring of the diffuse CO2 degassing was set up at Aguas Agrias in March 2001. Soil CO2 efflux and several meteorological and soil physical variables were measured in an hourly basis. Very significative pre-seismic and post-seismic relationships have been found in the observed diffuse CO2 efflux temporal variations related to the May 2001 seismic swarms. A sustained 50% increase on the average diffuse CO2 efflux was observed 8 days before the May 8, 5.1 magnitude earthquake. This pre-seismic behaviour may be considered a precursor of the May 2001 seismic swarm at San Vicente volcano. However, about a three-fold increase in the diffuse CO2 efflux was also observed after the intense seismicity recorded on May 8-9. These preliminary

  7. The Use of Genetics for the Management of a Recovering Population: Temporal Assessment of Migratory Peregrine Falcons in North America

    2010-11-01

    Alaska; Tanana River, Alaska; Porcupine River, Alaska; Yukon, Canada. 5Quebec, Newfoundland, and Labrador, Canada. 6Patagonia, Argentina. 7significant Fis...population decline. Biology Letters 2: 316–319. 102. Halbert ND, Derr JN (2008) Patterns of genetic variation in US federal bison herds . Molecular Ecology 17

  8. Pioneer study of population genetics of Rhodnius ecuadoriensis (Hemiptera: Reduviidae) from the central coastand southern Andean regions of Ecuador.

    Villacís, Anita G; Marcet, Paula L; Yumiseva, César A; Dotson, Ellen M; Tibayrenc, Michel; Brenière, Simone Frédérique; Grijalva, Mario J

    2017-09-01

    Effective control of Chagas disease vector populations requires a good understanding of the epidemiological components, including a reliable analysis of the genetic structure of vector populations. Rhodnius ecuadoriensis is the most widespread vector of Chagas disease in Ecuador, occupying domestic, peridomestic and sylvatic habitats. It is widely distributed in the central coast and southern highlands regions of Ecuador, two very different regions in terms of bio-geographical characteristics. To evaluate the genetic relationship among R. ecuadoriensis populations in these two regions, we analyzed genetic variability at two microsatellite loci for 326 specimens (n=122 in Manabí and n=204 in Loja) and the mitochondrial cytochrome b gene (Cyt b) sequences for 174 individuals collected in the two provinces (n=73 and=101 in Manabí and Loja respectively). The individual samples were grouped in populations according to their community of origin. A few populations presented positive F IS, possible due to Wahlund effect. Significant pairwise differentiation was detected between populations within each province for both genetic markers, and the isolation by distance model was significant for these populations. Microsatellite markers showed significant genetic differentiation between the populations of the two provinces. The partial sequences of the Cyt b gene (578bp) identified a total of 34 haplotypes among 174 specimens sequenced, which translated into high haplotype diversity (Hd=0.929). The haplotype distribution differed among provinces (significant Fisher's exact test). Overall, the genetic differentiation of R. ecuadoriensis between provinces detected in this study is consistent with the biological and phenotypic differences previously observed between Manabí and Loja populations. The current phylogenetic analysis evidenced the monophyly of the populations of R. ecuadoriensis within the R. pallescens species complex; R. pallescens and R. colombiensis were more

  9. Providers’ perspectives on inbound medical tourism in Central America and the Caribbean: factors driving and inhibiting sector development and their health equity implications

    Johnston, Rory; Crooks, Valorie A.; Cerón, Alejandro; Labonté, Ronald; Snyder, Jeremy; Núñez, Emanuel O.; Flores, Walter G.

    2016-01-01

    Background Many governments and health care providers worldwide are enthusiastic to develop medical tourism as a service export. Despite the popularity of this policy uptake, there is relatively little known about the specific local factors prospectively motivating and informing development of this sector. Objective To identify common social, economic, and health system factors shaping the development of medical tourism in three Central American and Caribbean countries and their health equity implications. Design In-depth, semi-structured interviews were conducted in Mexico, Guatemala, and Barbados with 150 health system stakeholders. Participants were recruited from private and public sectors working in various fields: trade and economic development, health services delivery, training and administration, and civil society. Transcribed interviews were coded using qualitative data management software, and thematic analysis was used to identify cross-cutting issues regarding the drivers and inhibitors of medical tourism development. Results Four common drivers of medical tourism development were identified: 1) unused capacity in existing private hospitals, 2) international portability of health insurance, vis-a-vis international hospital accreditation, 3) internationally trained physicians as both marketable assets and industry entrepreneurs, and 4) promotion of medical tourism by public export development corporations. Three common inhibitors for the development of the sector were also identified: 1) the high expense of market entry, 2) poor sector-wide planning, and 3) structural socio-economic issues such as insecurity or relatively high business costs and financial risks. Conclusion There are shared factors shaping the development of medical tourism in Central America and the Caribbean that help explain why it is being pursued by many hospitals and governments in the region. Development of the sector is primarily being driven by public investment promotion

  10. Providers’ perspectives on inbound medical tourism in Central America and the Caribbean: factors driving and inhibiting sector development and their health equity implications

    Rory Johnston

    2016-11-01

    Full Text Available Background: Many governments and health care providers worldwide are enthusiastic to develop medical tourism as a service export. Despite the popularity of this policy uptake, there is relatively little known about the specific local factors prospectively motivating and informing development of this sector. Objective: To identify common social, economic, and health system factors shaping the development of medical tourism in three Central American and Caribbean countries and their health equity implications. Design: In-depth, semi-structured interviews were conducted in Mexico, Guatemala, and Barbados with 150 health system stakeholders. Participants were recruited from private and public sectors working in various fields: trade and economic development, health services delivery, training and administration, and civil society. Transcribed interviews were coded using qualitative data management software, and thematic analysis was used to identify cross-cutting issues regarding the drivers and inhibitors of medical tourism development. Results: Four common drivers of medical tourism development were identified: 1 unused capacity in existing private hospitals, 2 international portability of health insurance, vis-a-vis international hospital accreditation, 3 internationally trained physicians as both marketable assets and industry entrepreneurs, and 4 promotion of medical tourism by public export development corporations. Three common inhibitors for the development of the sector were also identified: 1 the high expense of market entry, 2 poor sector-wide planning, and 3 structural socio-economic issues such as insecurity or relatively high business costs and financial risks. Conclusion: There are shared factors shaping the development of medical tourism in Central America and the Caribbean that help explain why it is being pursued by many hospitals and governments in the region. Development of the sector is primarily being driven by public

  11. Providers' perspectives on inbound medical tourism in Central America and the Caribbean: factors driving and inhibiting sector development and their health equity implications.

    Johnston, Rory; Crooks, Valorie A; Cerón, Alejandro; Labonté, Ronald; Snyder, Jeremy; Núñez, Emanuel O; Flores, Walter G

    2016-01-01

    Many governments and health care providers worldwide are enthusiastic to develop medical tourism as a service export. Despite the popularity of this policy uptake, there is relatively little known about the specific local factors prospectively motivating and informing development of this sector. To identify common social, economic, and health system factors shaping the development of medical tourism in three Central American and Caribbean countries and their health equity implications. In-depth, semi-structured interviews were conducted in Mexico, Guatemala, and Barbados with 150 health system stakeholders. Participants were recruited from private and public sectors working in various fields: trade and economic development, health services delivery, training and administration, and civil society. Transcribed interviews were coded using qualitative data management software, and thematic analysis was used to identify cross-cutting issues regarding the drivers and inhibitors of medical tourism development. Four common drivers of medical tourism development were identified: 1) unused capacity in existing private hospitals, 2) international portability of health insurance, vis-a-vis international hospital accreditation, 3) internationally trained physicians as both marketable assets and industry entrepreneurs, and 4) promotion of medical tourism by public export development corporations. Three common inhibitors for the development of the sector were also identified: 1) the high expense of market entry, 2) poor sector-wide planning, and 3) structural socio-economic issues such as insecurity or relatively high business costs and financial risks. There are shared factors shaping the development of medical tourism in Central America and the Caribbean that help explain why it is being pursued by many hospitals and governments in the region. Development of the sector is primarily being driven by public investment promotion agencies and the private health sector seeking

  12. Genetic Isolation among the Northwestern, Southwestern and Central-Eastern Indian Ocean Populations of the Pronghorn Spiny Lobster Panulirus penicillatus

    Muhamad Fadry Abdullah

    2014-05-01

    Full Text Available The pronghorn spiny lobster Panulirus penicillatus is a highly valuable species which is widely distributed in Indo-West Pacific and Eastern Pacific regions. Mitochondrial DNA control region sequences (566–571 bp were determined to investigate the population genetic structure of this species in the Indian Ocean. In total, 236 adult individuals of Panulirus penicillatus were collected from five locations in the Indian Ocean region. Almost all individuals had a unique haplotype. Intrapopulation haplotype (h and nucleotide (π diversities were high for each locality, ranging from h = 0.9986–1.0000 and π = 0.031593–0.043441. We observed distinct genetic isolation of population located at the northwestern and southwestern edge of the species range. Gene flow was found within localities in the central and eastern region of the Indian Ocean, probably resulting from an extended planktonic larval stage and prevailing ocean currents.

  13. Anomalous radon emanation at local and regional distances preceding earthquakes in the New Madrid seismic zone and adjacent areas of the central mid-continent of North America

    Steele, S.R.

    1984-01-01

    Anomalous soil-radon activity, including several spike-like surges over periods of 5, 2, and 2 1/2 months, and a year-long declining trend, preceded the most significant earthquakes of the central mid-continental region of North America during 1981 and early 1984. The observations of these events provide further evidence of (a) the existence of soil-radon anomalies precursory to the larger earthquakes in this intraplate region, (b) the utility of such anomalies in anticipating events of small to moderate magnitudes for the region, and (c) the occurrence of regional-scale strain events prior to some of the larger mid-continental earthquakes. A very recent radon anomaly, the strongest yet to be detected in the seven years of monitoring in the mid-continental region, occurred in the New Madrid seismic zone from mid-February through mid-June 1984. A 4.0 earthquake occurred one month after a peak in the radon activity. The amplitude and duration of the anomaly suggest that a significant change in the state of stress or strain may have occurred in the mid-continental region during 1984. (Auth.)

  14. WHO and national lists of essential medicines in Mexico, Central and South America, and the Caribbean: are they adequate to promote paediatric endocrinology and diabetes care?

    Rowlands, Amanda; Acosta-Gualandri, Alejandra; Guevara-Aguirre, Jaime; Chanoine, Jean-Pierre

    2016-01-01

    Paediatric endocrinology and diabetes is a paediatric specialty with less common conditions and higher cost medicines. Access to medicines for our specialty in low and middle income countries remains limited. We analysed the content of the WHO (children and adults) and of all available national Model Lists of Essential Medicines (EMLs) for Mexico, the Caribbean, Central and South America from a paediatric endocrinology and diabetes standpoint. A master list of medicines deemed necessary in paediatric endocrinology and diabetes was established and compared with the WHO and national EMLs, taking into account the gross national income. The WHO EMLs, which are largely recognised as an international benchmark and drive the content of the national EMLs, included many but not all medicines present on our master list. Interestingly, several national EMLs from richer countries included medicines that were not present in the WHO EMLs. Our analysis suggests that these medicines could be considered by the WHO for inclusion in their EMLs, which may promote the adoption of more medicines by individual countries. We also propose several changes to the WHO and national EMLs that could facilitate access to medicines in our specialty: age cut-off for a child using physical maturity rather than a set age limit; greater standardisation of the formatting of the national EMLs for easier comparison and collaborations between countries; greater emphasis on age-specificity and population-specificity for some medicines; and formatting of the EMLs in a disease-focused manner rather than as individual medicines. PMID:28588968

  15. Transboundary aquifers: the response of international law and legal voids in Central America; Acuiferos transfronterizos: respuestas desde el derecho internacional y vacios en Centroamerica

    Boeglin, N.

    2012-11-01

    Central America is one of the regions of the world that will suffer the impact of climate change much more than others. The adoption of clear rules on the use of transboundary aquifers and on the need to preserve these groundwater reservoirs from serious pollution by the various states in the region is absolutely essential. Despite the lack of any bilateral or regional frameworks to rule on this issue, many general regulations have been adopted within the international framework of the United Nations that are applicable to shared surface and groundwater resources as well as to transboundary aquifers. The case of the Las Crucitas project in Costa Rica, halted by domestic tribunals thanks to the decisive action of its civilian society, reflects a clear lack of technical information concerning aquifers in Costa Rica, and probably in many other states in the region, despite the very valuable efforts being undertaken by the OAS and UNESCO under the aegis of the ISARM project for the Latin American region.

  16. Collection, Characterization and Use of Genetic Bariation in Chilean Bean Germplasm (Phaseolus vulgaris L.)

    Bascur B., Gabriel; Tay U., Juan

    2005-01-01

    Recently performed studies on the type of seed protein present from several origins and their morphological traits have shown that the common bean (Phaseolus vulgaris L.) is native to America, being a species without a specific center of origin and with two areas of domestication: Central America and South America. In this last center, three strains were determined, one of them is called "the Chilean strain", which as noted is a sub-center of genetic diversity for this species. With the purpo...

  17. Population Genetic Structure of Cnesterodon decemmaculatus (Poeciliidae): A Freshwater Look at the Pampa Biome in Southern South America.

    Ramos-Fregonezi, Aline M C; Malabarba, Luiz R; Fagundes, Nelson J R

    2017-01-01

    The Pampas is a Neotropical biome formed primarily by low altitude grasslands and encompasses the southernmost portion of Brazil, Uruguay, and part of Argentina. Despite the high level of endemism, and its significant environmental heterogeneity, Pampean species are underrepresented in phylogeographic studies, especially aquatic organisms. The Pampean hydrological system resulted from a long history of tectonism, climate, and sea level changes since the Neogene. In this study, we examined the population genetic structure of Cnesterodon decemmaculatus , a freshwater fish species that occurs throughout most of the Pampa biome. We characterized mitochondrial and autosomal genetic lineages in populations sampled from Southern Brazil and Uruguay to investigate (1) the correspondence between current drainage systems and evolutionary lineages, (2) the demographic history for each genetic lineage, and (3) the temporal depth of these lineages. Overall, we found that the major evolutionary lineages in this species are strongly related to the main Pampean drainage systems, even though stream capture events may have affected the distribution of genetic lineages among drainages. There was evidence for recent population growth in the lineages occupying drainages closest to the shore, which may indicate the effect of quaternary sea-level changes. In general, divergence time estimates among evolutionary lineages were shallow, ranging from 20,000 to 800,000 years before present, indicating a geologically recent history for this group, as previously reported in other Pampean species. A Bayesian phylogeographical reconstruction suggested that an ancestral lineage probably colonized the Uruguay River Basin, and then expanded throughout the Pampas. This evolutionary scenario may represent useful starting models for other freshwater species having a similar distribution.

  18. Population Genetic Structure of Cnesterodon decemmaculatus (Poeciliidae: A Freshwater Look at the Pampa Biome in Southern South America

    Aline M. C. Ramos-Fregonezi

    2017-12-01

    Full Text Available The Pampas is a Neotropical biome formed primarily by low altitude grasslands and encompasses the southernmost portion of Brazil, Uruguay, and part of Argentina. Despite the high level of endemism, and its significant environmental heterogeneity, Pampean species are underrepresented in phylogeographic studies, especially aquatic organisms. The Pampean hydrological system resulted from a long history of tectonism, climate, and sea level changes since the Neogene. In this study, we examined the population genetic structure of Cnesterodon decemmaculatus, a freshwater fish species that occurs throughout most of the Pampa biome. We characterized mitochondrial and autosomal genetic lineages in populations sampled from Southern Brazil and Uruguay to investigate (1 the correspondence between current drainage systems and evolutionary lineages, (2 the demographic history for each genetic lineage, and (3 the temporal depth of these lineages. Overall, we found that the major evolutionary lineages in this species are strongly related to the main Pampean drainage systems, even though stream capture events may have affected the distribution of genetic lineages among drainages. There was evidence for recent population growth in the lineages occupying drainages closest to the shore, which may indicate the effect of quaternary sea-level changes. In general, divergence time estimates among evolutionary lineages were shallow, ranging from 20,000 to 800,000 years before present, indicating a geologically recent history for this group, as previously reported in other Pampean species. A Bayesian phylogeographical reconstruction suggested that an ancestral lineage probably colonized the Uruguay River Basin, and then expanded throughout the Pampas. This evolutionary scenario may represent useful starting models for other freshwater species having a similar distribution.

  19. Comparative mtDNA phylogeography of neotropical freshwater fishes: testing shared history to infer the evolutionary landscape of lower Central America.

    Bermingham, E; Martin, A P

    1998-04-01

    Historical biogeography seeks to explain contemporary distributions of taxa in the context of intrinsic biological and extrinsic geological and climatic factors. To decipher the relative importance of biological characteristics vs. environmental conditions, it is necessary to ask whether groups of taxa with similar distributions share the same history of diversification. Because all of the taxa will have shared the same climatic and geological history, evidence of shared history across multiple species provides an estimate of the role of extrinsic factors in shaping contemporary biogeographic patterns. Similarly, differences in the records of evolutionary history across species will probably be signatures of biological differences. In this study, we focus on inferring the evolutionary history for geographical populations and closely related species representing three genera of primary freshwater fishes that are widely distributed in lower Central America (LCA) and northwestern Colombia. Analysis of mitochondrial gene trees provides the opportunity for robust tests of shared history across taxa. Moreover, because mtDNA permits inference of the temporal scale of diversification we can test hypotheses regarding the chronological development of the Isthmian corridor linking North and South America. We have focused attention on two issues. First, we show that many of the distinct populations of LCA fishes diverged in a relatively brief period of time thus limiting the phylogenetic signal available for tests of shared history. Second, our results provide reduced evidence of shared history when all drainages are included in the analysis because of inferred dispersion events that obscure the evolutionary history among drainage basins. When we restrict the analysis to areas that harbour endemic mitochondrial lineages, there is evidence of shared history across taxa. We hypothesize that there were two to three distinct waves of invasion into LCA from putative source

  20. Analysis of genetic and environmental effects on hybrid poplar rooting in Central and Northern Minnesota, USA

    Ronald S., Jr. Zalesny; Don Riemenschneider; Edmund Bauer

    2000-01-01

    We studied genetic and environmental effects on adventitious root initiation and growth because rooting is biologically prerequisite to the establishment of hybrid poplar plantations. Six clones from two pedigrees (pure Populus deltoides "cottonwoods" and P. deltoides x P. maximowiczii hybrids) were...

  1. On the number of New World founders: a population genetic portrait of the peopling of the Americas.

    Hey, Jody

    2005-06-01

    The founding of New World populations by Asian peoples is the focus of considerable archaeological and genetic research, and there persist important questions on when and how these events occurred. Genetic data offer great potential for the study of human population history, but there are significant challenges in discerning distinct demographic processes. A new method for the study of diverging populations was applied to questions on the founding and history of Amerind-speaking Native American populations. The model permits estimation of founding population sizes, changes in population size, time of population formation, and gene flow. Analyses of data from nine loci are consistent with the general portrait that has emerged from archaeological and other kinds of evidence. The estimated effective size of the founding population for the New World is fewer than 80 individuals, approximately 1% of the effective size of the estimated ancestral Asian population. By adding a splitting parameter to population divergence models it becomes possible to develop detailed portraits of human demographic history. Analyses of Asian and New World data support a model of a recent founding of the New World by a population of quite small effective size.

  2. Ecological hybrid speciation in central-European species of Bolboschoenus: genetic and morphological evaluation

    Píšová, Soňa; Hroudová, Zdenka; Chumová, Zuzana; Fér, T.

    2017-01-01

    Roč. 89, č. 1 (2017), s. 17-39 ISSN 0032-7786 R&D Projects: GA ČR GB14-36079G Institutional support: RVO:67985939 Keywords : AFLP * Bolboschoenus * central Europe * speciation * model-based clustering * morfometrics Subject RIV: EF - Botanics OBOR OECD: Plant sciences, botany Impact factor: 3.000, year: 2016

  3. Genetic variability of central-western European pine marten (Martes martes) populations

    Pertoldi, Cino; Elschot, Kelly; Ruiz-Gonzalez, Aritz; van de Zande, Louis; Zalewski, Andrzej; Munoz, Joaquin; Madsen, Aksel Bo; Loeschcke, Volker; de Groot, Arjen; Bijlsma, Rudolf

    2014-01-01

    Recent studies highlighted the potential role of cryptic glacial refugia for temperate taxa in Europe beyond the Mediterranean peninsulas. To further investigate phylogeographic features of the European pine marten (Martes martes) in previously identified cryptic refugia located in central-western

  4. Genetic improvement of hardwood fiber production in the north-central region: potentials and breeding alternatives

    R.E., Jr. Farmer

    1973-01-01

    In the Lake States, aspens are now growing towards senility Faster than they are being harvested (Groff 1966). In the Central States, wood processing residues have recently supplied about one-half of the area's hardwood fiber requirement (Blyth 1970), thus allowing hardwood growing stock to continue its recuperation. In fact, the national hardwood fiber supply...

  5. Chloroplast DNA variation of oaks in western Central Europe and genetic consequences of human influences

    König, A.O.; Ziegenhagen, B.; Dam, van B.C.; Csaikl, U.M.; Coart, E.; Degen, B.; Burg, K.; Vries, de S.M.G.; Petit, R.J.

    2002-01-01

    Oak chloroplast DNA (cpDNA) variation was studied in a grid-based inventory in western Central Europe, including Belgium, The Netherlands, Luxembourg, Germany, the Czech Republic, and the northern parts of Upper and Lower Austria. A total of 2155 trees representing 426 populations of Quercus robur

  6. Genetic species identification in weatherfish and first molecular confirmation of Oriental Weatherfish Misgurnus anguillicaudatus (Cantor, 1842 in Central Europe

    Belle Christina C.

    2017-01-01

    Full Text Available The Oriental Weatherfish is considered a globally invasive fish species. In Europe, several reported feral populations of Oriental Weatherfish display an overlapping distribution range with native weatherfish Misgurnus fossilis, a declining species of international conservation and aquatic management concern. Morphologically distinguishing the different weatherfish species can be difficult, as their coloration is highly variable, many species reveal high phenotypic plasticity, and morphological traits like coloration might be not obvious or might be degraded during field sampling and after preservation. Herein, we analysed suspicious weatherfish specimens from southern Germany, demonstrating the usefulness of molecular genetic species identifications in this genus. We present the first molecular genetic species record of Misgurnus anguillicaudatus in Central Europe, and confirm the range expansion of Oriental Weatherfish into the river Inn catchment in southern Germany. As accurate species identification is crucial both in the context of monitoring and conserving native endangered species, and in early detection and prevention of biological invasion, we suggest the standard use of genetic species identification if morphological traits are not obvious.

  7. Uniparental genetic heritage of belarusians: encounter of rare middle eastern matrilineages with a central European mitochondrial DNA pool.

    Kushniarevich, Alena; Sivitskaya, Larysa; Danilenko, Nina; Novogrodskii, Tadeush; Tsybovsky, Iosif; Kiseleva, Anna; Kotova, Svetlana; Chaubey, Gyaneshwer; Metspalu, Ene; Sahakyan, Hovhannes; Bahmanimehr, Ardeshir; Reidla, Maere; Rootsi, Siiri; Parik, Jüri; Reisberg, Tuuli; Achilli, Alessandro; Hooshiar Kashani, Baharak; Gandini, Francesca; Olivieri, Anna; Behar, Doron M; Torroni, Antonio; Davydenko, Oleg; Villems, Richard

    2013-01-01

    Ethnic Belarusians make up more than 80% of the nine and half million people inhabiting the Republic of Belarus. Belarusians together with Ukrainians and Russians represent the East Slavic linguistic group, largest both in numbers and territory, inhabiting East Europe alongside Baltic-, Finno-Permic- and Turkic-speaking people. Till date, only a limited number of low resolution genetic studies have been performed on this population. Therefore, with the phylogeographic analysis of 565 Y-chromosomes and 267 mitochondrial DNAs from six well covered geographic sub-regions of Belarus we strove to complement the existing genetic profile of eastern Europeans. Our results reveal that around 80% of the paternal Belarusian gene pool is composed of R1a, I2a and N1c Y-chromosome haplogroups - a profile which is very similar to the two other eastern European populations - Ukrainians and Russians. The maternal Belarusian gene pool encompasses a full range of West Eurasian haplogroups and agrees well with the genetic structure of central-east European populations. Our data attest that latitudinal gradients characterize the variation of the uniparentally transmitted gene pools of modern Belarusians. In particular, the Y-chromosome reflects movements of people in central-east Europe, starting probably as early as the beginning of the Holocene. Furthermore, the matrilineal legacy of Belarusians retains two rare mitochondrial DNA haplogroups, N1a3 and N3, whose phylogeographies were explored in detail after de novo sequencing of 20 and 13 complete mitogenomes, respectively, from all over Eurasia. Our phylogeographic analyses reveal that two mitochondrial DNA lineages, N3 and N1a3, both of Middle Eastern origin, might mark distinct events of matrilineal gene flow to Europe: during the mid-Holocene period and around the Pleistocene-Holocene transition, respectively.

  8. The perspectives for genetically modified cellulosic biofuels in the Central European conditions

    Bláhová, P.; Janda, K.; Krištoufek, Ladislav

    2014-01-01

    Roč. 60, č. 6 (2014), s. 247-259 ISSN 0139-570X Grant - others:GA ČR(CZ) GAP402/11/0948 Program:GA Institutional support: RVO:67985556 Keywords : ellulosic biofuels * genetic modifications Subject RIV: AH - Economics Impact factor: 0.442, year: 2014 http://library.utia.cas.cz/separaty/2014/E/kristoufek-0433521.pdf

  9. HIV-1 Genetic Diversity and Transmitted Drug Resistance Mutations among Patients from the North, Central and South Regions of Angola

    Afonso, Joana Morais; Bello, Gonzalo; Guimarães, Monick L.; Sojka, Marta; Morgado, Mariza G.

    2012-01-01

    Background Angola presents a very complex HIV-1 epidemic characterized by the co-circulation of several HIV-1 group M subtypes, intersubtype recombinants and unclassified (U) variants. The viral diversity outside the major metropolitan regions (Luanda and Cabinda) and the prevalence of transmitted drug resistance mutations (DRM) since the introduction of HAART in 2004, however, has been barely studied. Methods One hundred and one individuals from the Central (n = 44), North (n = 35), and South (n = 22) regions of Angola were diagnosed as HIV-1 positive and had their blood collected between 2008 and 2010, at one of the National Referral Centers for HIV diagnosis, the Kifangondo Medical Center, located in the border between the Luanda and Bengo provinces. Angolan samples were genotyped based on phylogenetic and bootscanning analyses of the pol (PR/RT) gene and their drug resistance profile was analyzed. Results Among the 101 samples analyzed, 51% clustered within a pure group M subtype, 42% were classified as intersubtype recombinants, and 7% were denoted as U. We observed an important variation in the prevalence of different HIV-1 genetic variants among country regions, with high frequency of subtype F1 in the North (20%), intersubtype recombinants in the Central (42%), and subtype C in the South (45%). Statistically significant difference in HIV-1 clade distribution was only observed in subtype C prevalence between North vs South (p = 0.0005) and Central vs South (p = 0.0012) regions. DRM to NRTI and/or NNRTI were detected in 16.3% of patients analyzed. Conclusions These results demonstrate a heterogeneous distribution of HIV-1 genetic variants across different regions in Angola and also revealed an unexpected high frequency of DRM to RT inhibitors in patients that have reported no antiretroviral usage, which may decrease the efficiency of the standard first-line antiretroviral regimens currently used in the country. PMID:22952625

  10. A novel educational strategy targeting health care workers in underserved communities in Central America to integrate HIV into primary medical care.

    Flys, Tamara; González, Rosalba; Sued, Omar; Suarez Conejero, Juana; Kestler, Edgar; Sosa, Nestor; McKenzie-White, Jane; Monzón, Irma Irene; Torres, Carmen-Rosa; Page, Kathleen

    2012-01-01

    Current educational strategies to integrate HIV care into primary medical care in Central America have traditionally targeted managers or higher-level officials, rather than local health care workers (HCWs). We developed a complementary online and on-site interactive training program to reach local HCWs at the primary care level in underserved communities. The training program targeted physicians, nurses, and community HCWs with limited access to traditional onsite training in Panama, Nicaragua, Dominican Republic, and Guatemala. The curriculum focused on principles of HIV care and health systems using a tutor-supported blended educational approach of an 8-week online component, a weeklong on-site problem-solving workshop, and individualized project-based interventions. Of 258 initially active participants, 225 (225/258=87.2%) successfully completed the online component and the top 200 were invited to the on-site workshop. Of those, 170 (170/200=85%) attended the on-site workshop. In total, 142 completed all three components, including the project phase. Quantitative and qualitative evaluation instruments included knowledge assessments, reflexive essays, and acceptability surveys. The mean pre and post-essay scores demonstrating understanding of social determinants, health system organization, and integration of HIV services were 70% and 87.5%, respectively, with an increase in knowledge of 17.2% (pstructure, and effectiveness in improving their HIV-related knowledge and skills. This innovative curriculum utilized technology to target HCWs with limited access to educational resources. Participants benefited from technical skills acquired through the process, and could continue working within their underserved communities while participating in the online component and then implement interventions that successfully converted theoretical knowledge to action to improve integration of HIV care into primary care.

  11. Isotopic and geochemical evolution of ground and surface waters in a karst dominated geological setting: a case study from Belize, Central America

    Marfia, A.M.; Krishnamurthy, R.V.; Atekwana, E.A.; Panton, W.F.

    2004-01-01

    Analysis of stable isotopes and major ions in groundwater and surface waters in Belize, Central America was carried out to identify processes that may affect drinking water quality. Belize has a subtropical rainforest/savannah climate with a varied landscape composed predominantly of carbonate rocks and clastic sediments. Stable oxygen (δ 18 O) and hydrogen (δD) isotope ratios for surface and groundwater have a similar range and show high d-excess (10-40.8%o). The high d-excess in water samples suggest secondary continental vapor flux mixing with incoming vapor from the Caribbean Sea. Model calculations indicate that moisture derived from continental evaporation contributes 13% to overhead vapor load. In surface and groundwater, concentrations of dissolved inorganic carbon (DIC) ranged from 5.4 to 112.9 mg C/l and δ 13 C DIC ranged from -7.4 to -17.4%o. SO 4 2 , Ca 2+ and Mg 2+ in the water samples ranged from 2-163, 2-6593 and 2-90 mg/l, respectively. The DIC and δ 13 C DIC indicate both open and closed system carbonate evolution. Combined δ 13 C DIC and Ca 2+ , Mg 2+ , and SO 4 2- suggest additional groundwater evolution by gypsum dissolution and calcite precipitation. The high SO 4 2- content of some water samples indicates regional geologic control on water quality. Similarity in the range of δ 18 O, δD and δ 13 C DIC for surface waters and groundwater used for drinking water supply is probably due to high hydraulic conductivities of the karstic aquifers. The results of this study indicate rapid recharge of groundwater aquifers, groundwater influence on surface water chemistry and the potential of surface water to impact groundwater quality and vise versa

  12. Confirmed clinical case of chronic kidney disease of nontraditional causes in agricultural communities in Central America: a case definition for surveillance

    Alejandro Ferreiro

    Full Text Available ABSTRACT Over the last 20 years, many reports have described an excess of cases of chronic kidney disease (CKD in the Pacific coastal area of Central America, mainly affecting male farmworkers and signaling a serious public health problem. Most of these cases are not associated with traditional risk factors for CKD, such as aging, diabetes mellitus, and hypertension. This CKD of nontraditional causes (CKDnT might be linked to environmental and/or occupational exposure or working conditions, limited access to health services, and poverty. In response to a resolution approved by the Directing Council of the Pan American Health Organization (PAHO in 2013, PAHO, the U.S. Centers for Disease Control and Prevention, and the Latin American Society of Nephrology and Hypertension (SLANH organized a consultation process in order to expand knowledge on the epidemic of CKDnT and to develop appropriate surveillance instruments. The Clinical Working Group from SLANH was put in charge of finding a consensus definition of a confirmed clinical case of CKDnT. The resulting definition establishes mandatory criteria and exclusion criteria necessary for classifying a case of CKDnT. The definition includes a combination of universally accepted definitions of CKD and the main clinical manifestations of CKDnT. Based on the best available evidence, the Clinical Working Group also formulated general recommendations about clinical management that apply to any patient with CKDnT. Adhering to the definition of a confirmed clinical case of CKDnT and implementing it appropriately is expected to be a powerful instrument for understanding the prevalence of the epidemic, evaluating the results of interventions, and promoting appropriate advocacy and planning efforts.

  13. Confirmed clinical case of chronic kidney disease of nontraditional causes in agricultural communities in Central America: a case definition for surveillance.

    Ferreiro, Alejandro; Álvarez-Estévez, Guillermo; Cerdas-Calderón, Manuel; Cruz-Trujillo, Zulma; Mena, Elio; Reyes, Marina; Sandoval-Diaz, Mabel; Sánchez-Polo, Vicente; Valdés, Régulo; Ordúnez, Pedro

    2016-11-01

    Over the last 20 years, many reports have described an excess of cases of chronic kidney disease (CKD) in the Pacific coastal area of Central America, mainly affecting male farmworkers and signaling a serious public health problem. Most of these cases are not associated with traditional risk factors for CKD, such as aging, diabetes mellitus, and hypertension. This CKD of nontraditional causes (CKDnT) might be linked to environmental and/or occupational exposure or working conditions, limited access to health services, and poverty. In response to a resolution approved by the Directing Council of the Pan American Health Organization (PAHO) in 2013, PAHO, the U.S. Centers for Disease Control and Prevention, and the Latin American Society of Nephrology and Hypertension (SLANH) organized a consultation process in order to expand knowledge on the epidemic of CKDnT and to develop appropriate surveillance instruments. The Clinical Working Group from SLANH was put in charge of finding a consensus definition of a confirmed clinical case of CKDnT. The resulting definition establishes mandatory criteria and exclusion criteria necessary for classifying a case of CKDnT. The definition includes a combination of universally accepted definitions of CKD and the main clinical manifestations of CKDnT. Based on the best available evidence, the Clinical Working Group also formulated general recommendations about clinical management that apply to any patient with CKDnT. Adhering to the definition of a confirmed clinical case of CKDnT and implementing it appropriately is expected to be a powerful instrument for understanding the prevalence of the epidemic, evaluating the results of interventions, and promoting appropriate advocacy and planning efforts.

  14. Clinical and Virologic Outcomes After Changes in First Antiretroviral Regimen at 7 Sites in the Caribbean, Central and South America Network.

    Wolff, Marcelo; Shepherd, Bryan E; Cortés, Claudia; Rebeiro, Peter; Cesar, Carina; Wagner Cardoso, Sandra; Pape, Jean W; Padgett, Denis; Sierra-Madero, Juan; Echevarria, Juan; McGowan, Catherine C

    2016-01-01

    HIV-infected persons in resource-limited settings may experience high rates of antiretroviral therapy (ART) change, particularly because of toxicity or other nonfailure reasons. Few reports address patient outcomes after these modifications. HIV-infected adults from the 7 Caribbean, Central and South America network clinical cohorts who modified >1 drug from the first ART regimen (ART-1) for any reason thereby starting a second regimen (ART-2) were included. We assessed cumulative incidence of, and factors associated with, death, virologic failure (VF), and regimen change after starting ART-2. Five thousand five hundred sixty-five ART-naive highly active ART initiators started ART-2 after a median of 9.8 months on ART-1; 39% changed to ART-2 because of toxicity and 11% because of failure. Median follow-up after starting ART-2 was 2.9 years; 45% subsequently modified ART-2. Cumulative incidences of death at 1, 3, and 5 years after starting ART-2 were 5.1%, 8.4%, and 10.5%, respectively. In adjusted analyses, death was associated with older age, clinical AIDS, lower CD4 at ART-2 start, earlier calendar year, and starting ART-2 because of toxicity (adjusted hazard ratio = 1.5 vs. failure, 95% confidence interval: 1.0 to 2.1). Cumulative incidences of VF after 1, 3, and 5 years were 9%, 19%, and 25%. In adjusted analyses, VF was associated with younger age, earlier calendar year, lower CD4 at the start of ART-2, and starting ART-2 because of failure (adjusted hazard ratio = 2.1 vs. toxicity, 95% confidence interval: 1.5 to 2.8). Among patients modifying the first ART regimen, risks of subsequent modifications, mortality, and virologic failure were high. Access to improved antiretrovirals in the region is needed to improve initial treatment success.

  15. Description of the Oocysts of Three New Species of Eimeria (Apicomplexa: Eimeriidae from Iguanid Lizards (Sauria: Iguanidae of Central and South America

    Daszak P

    1998-01-01

    Full Text Available Three new species of Eimeria are described from iguanid lizards of Central and South America. The oocysts of each species have no micropyles or residua and the sporocysts lack Stieda bodies, but all have a sporocyst residuum. Eimeria sanctaluciae n.sp. was found in the St. Lucia tree lizard, Anolis luciae, collected from the Maria Islands, Lesser Antilles. The oocysts are spherical to subspherical, averaging 17.3 x 16.5 µm, with a single layered colourless wall; about 60% contain polar granules. The sporocysts are ellipsoidal and average 7.7 x 5.5 µm. Eimeria liolaemi n.sp. was recovered from the blue-gold swift, Liolaemus taenius, from Chile. The oocysts are spherical to subspherical, measuring 21 x 20.1 µm with a single-layered colourless wall. The sporocysts are subspherical and average 7.4 x 6.8 µm. Eimeria caesicia n.sp. is described from the Brazilian collared iguanid, Tropidurus torquatus. The oocysts measure 27.4 x 23.7 µm, are spherical to subspherical, with a bilayered wall, the outer surface of which appears pale blue in colour, the thin, inner wall appearing brown, when viewed by direct light under the optical microscope. The sporocysts are subspherical and average 9.4 x 7.2 µm. Unnamed polysporocystid oocysts with dizoic sporocysts are reported from the faeces of the lesser St. Vincent tree lizard, Anolis trinitatis and the possibility of spurious parasitism briefly discussed. In addition, oocysts of an unnamed Isospora sp. with a smooth oocyst wall which closely resembles I. reui were recovered from A. trinitatis.

  16. Clinical and virologic outcomes after changes in first antiretroviral regimen at 7 sites in the Caribbean, Central and South America Network (CCASAnet)

    Wolff, Marcelo; Shepherd, Bryan E.; Cortés, Claudia; Rebeiro, Peter; Cesar, Carina; Cardoso, Sandra Wagner; Pape, Jean W.; Padgett, Denis; Sierra-Madero, Juan; Echevarria, Juan; McGowan, Catherine C.

    2015-01-01

    Background HIV-infected persons in lower income countries may experience high rates of antiretroviral therapy (ART) change, particularly due to toxicity or other non-failure reasons. Few reports address patient outcomes after these modifications. Methods HIV-infected adults from 7 Caribbean, Central and South America network (CCASAnet) clinical cohorts who modified > or = 1 drug from first ART regimen (ART-1) for any reason thereby starting a second regimen (ART-2) were included. Results 5,565 ART-naïve HAART initiators started ART-2 after a median of 9.8 months on ART-1; 39% changed to ART-2 due to toxicity and 11% due to failure. Median follow-up after starting ART-2 was 2.9 years; 45% subsequently modified ART-2. Cumulative incidences of death at 1, 3, and 5 years after starting ART-2 were 5.1%, 8.4% and 10.5%, respectively. In adjusted analyses, death was associated with older age, clinical AIDS, lower CD4 at ART-2 start, earlier calendar year, and starting ART-2 because of toxicity (adjusted hazard ratio[aHR]=1.5 vs. failure, 95% confidence interval[CI]=1.0–2.1). Cumulative incidences of VF after 1, 3, and 5 years were 9%, 19%, and 25%. In adjusted analyses, VF was associated with younger age, earlier calendar year, lower CD4 at start of ART-2, and starting ART-2 because of failure (aHR=2.1 vs. toxicity, 95% CI=1.5–2.8). Conclusions Among patients modifying first ART regimen, risks of subsequent modifications, mortality, and virologic failure were high. Access to improved antiretrovirals in the region is needed to improve initial treatment success. PMID:26761273

  17. Health care providers and human trafficking: what do they know, what do they need to know? Findings from the middle East, the Caribbean, and central america.

    Viergever, Roderik F; West, Haley; Borland, Rosilyne; Zimmerman, Cathy

    2015-01-01

    Human trafficking is a crime that commonly results in acute and chronic physical and psychological harm. To foster more informed health sector responses to human trafficking, training sessions for health care providers were developed and pilot-tested in the Middle East, Central America, and the Caribbean. This study presents the results of an investigation into what health care providers knew and needed to know about human trafficking as part of that training program. Participants attended one of seven two-day training courses in Antigua and Barbuda, Belize, Costa Rica, Egypt, El Salvador, Guyana, and Jordan. We assessed participants' knowledge about human trafficking and opinions about appropriate responses in trafficking cases via questionnaires pre-training, and considered participant feedback about the training post-training. 178 participants attended the trainings. Pre-training questionnaires were completed by 165 participants (93%) and post-training questionnaires by 156 participants (88%). Pre-training knowledge about health and human trafficking appeared generally high for topics such as the international nature of trafficking and the likelihood of poor mental health outcomes among survivors. However, many participants had misconceptions about the characteristics of trafficked persons and a provider's role in responding to cases of trafficking. The most valued training components included the "Role of the Health Provider," "Basic Definitions and Concepts," and "Health Consequences of Trafficking." Training health care providers on caring for trafficked persons has the potential to improve practitioners' knowledge about human trafficking and its health consequences, and to increase safe practices when responding in cases of trafficking. This study provides lessons for the design of training programs on human trafficking that aim to help health care providers identify and refer victims, and provide care for survivors.

  18. Magma-Tectonic Interactions along the Central America Volcanic Arc: Insights from the August 1999 Magmatic and Tectonic Event at Cerro Negro, Nicaragua

    La Femina, P.; Connor, C.; Strauch, W.

    2002-12-01

    Volcanic vent alignments form parallel to the direction of maximum horizontal stress, accommodating extensional strain via dike injection. Roughly east-west extension within the Central America Volcanic Arc is accommodated along north-northwest-trending basaltic vent alignments. In Nicaragua, these alignments are located in a northwest-trending zone of dextral shear, with shear accommodated along northeast trending bookshelf faults. The recent eruption of Cerro Negro volcano, Nicaragua and Marabios Range seismic swarm revealed the interaction of these fault systems. A low energy (VEI 1), small volume (0.001 km3 DRE) eruption of highly crystalline basalt occurred at Cerro Negro volcano, Nicaragua, August 5-7, 1999. This eruption followed three tectonic earthquakes (each Mw 5.2) in the vicinity of Cerro Negro hours before the onset of eruptive activity. The temporal and spatial pattern of microseismicity and focal mechanisms of the Mw 5.2 earthquakes suggests the activation of northeast-trending faults northwest and southeast of Cerro Negro within the Marabios Range. The eruption was confined to three new vents formed on the southern flank of Cerro Negro along a preexisting north-northwest trending alignment; the El Hoyo alignment of cinder cones, maars and explosion craters. Surface ruptures formed > 1 km south and southeast of the new vents suggest dike injection. Numerical simulations of conduit flow illustrate that the observed effusion rates (up to 65 ms-1) and fountain heights (50-300 m) can be achieved by eruption of magma with little or no excess fluid pressure, in response to tectonic strain. These observations and models suggest that 1999 Cerro Negro activity is an excellent example of tectonically induced small-volume eruptions in an arc setting.

  19. Children’s Migration to the United States from Mexico and Central America: Evidence from the Mexican and Latin American Migration Projects

    Katharine M. Donato

    2015-02-01

    Full Text Available In light of rising numbers of unaccompanied minors at the Mexico-US border in 2014, this article examines child migration from Mexico, Guatemala, El Salvador, Costa Rica, and Nicaragua. Using data from the Mexican and Latin American Migration Projects that permit us to go beyond simple descriptive analysis about children apprehended at the border, we investigate the extent to which children from these countries: (1 enter without legal authorization to do so; (2 are more likely to cross the border now than in the past; and (3 are tied to their parents’ migration. In theory, if immigration and refugee protections worked well for children and offered them legal pathways to reunify with their families, then we would expect low levels of unauthorized entry and no dramatic shifts over time. However, our examination of child migration shows that it is strongly linked to unauthorized entry, period of entry, and parents’ US experience.The findings show that the migration of children is closely linked to their parents’ migration history. Although the overall likelihood of a Mexican child making a first US trip is quite low, it is practically non-existent for children whose parents have no US experience. Thus, the increase in child migration from Central America, and the continued high levels of child migration from Mexico result from widespread migration networks and the United States’ long-standing reliance on the children’s parents as immigrant workers. The findings suggest that these children need protection in the form of family reunification and permanent legal status.

  20. PEER NGA-East Overview: Development of a Ground Motion Characterization Model (Ground Motion Prediction Equations) for Central and Eastern North America

    Goulet, C. A.; Abrahamson, N. A.; Al Atik, L.; Atkinson, G. M.; Bozorgnia, Y.; Graves, R. W.; Kuehn, N. M.; Youngs, R. R.

    2017-12-01

    The Next Generation Attenuation project for Central and Eastern North America (CENA), NGA-East, is a major multi-disciplinary project coordinated by the Pacific Earthquake Engineering Research Center (PEER). The project was co-sponsored by the U.S. Nuclear Regulatory Commission (NRC), the U.S. Department of Energy (DOE), the Electric Power Research Institute (EPRI) and the U.S. Geological Survey (USGS). NGA-East involved a large number of participating researchers from various organizations in academia, industry and government and was carried-out as a combination of 1) a scientific research project and 2) a model-building component following the NRC Seismic Senior Hazard Analysis Committee (SSHAC) Level 3 process. The science part of the project led to several data products and technical reports while the SSHAC component aggregated the various results into a ground motion characterization (GMC) model. The GMC model consists in a set of ground motion models (GMMs) for median and standard deviation of ground motions and their associated weights, combined into logic-trees for use in probabilistic seismic hazard analyses (PSHA). NGA-East addressed many technical challenges, most of them related to the relatively small number of earthquake recordings available for CENA. To resolve this shortcoming, the project relied on ground motion simulations to supplement the available data. Other important scientific issues were addressed through research projects on topics such as the regionalization of seismic source, path and attenuation of motions, the treatment of variability and uncertainties and on the evaluation of site effects. Seven working groups were formed to cover the complexity and breadth of topics in the NGA-East project, each focused on a specific technical area. This presentation provides an overview of the NGA-East research project and its key products.

  1. Health care providers and human trafficking: what do they know, what do they need to know? Findings from the Middle East, the Caribbean and Central America.

    Roderik F Viergever

    2015-01-01

    Full Text Available BackgroundHuman trafficking is a crime that commonly results in acute and chronic physical and psychological harm. To foster more informed health sector responses to human trafficking, training sessions for health care providers were developed and pilot-tested in the Middle East, Central America and the Caribbean. This study presents the results of an investigation into what health care providers knew and needed to know about human trafficking as part of that training program.MethodsParticipants attended one of seven two-day training courses in Antigua and Barbuda, Belize, Costa Rica, Egypt, El Salvador, Guyana and Jordan. We assessed participants’ knowledge about human trafficking and opinions about appropriate responses in trafficking cases via questionnaires pre-training, and considered participant feedback about the training post-training. Results178 participants attended the trainings. Pre-training questionnaires were completed by 165 participants (93% and post-training questionnaires by 156 participants (88%. Pre-training knowledge about health and human trafficking appeared generally high for topics such as the international nature of trafficking and the likelihood of poor mental health outcomes among survivors. However, many participants had misconceptions about the characteristics of trafficked persons and a provider’s role in responding to cases of trafficking. The most valued training components included the Role of the Health Provider, Basic Definitions and Concepts and Health Consequences of Trafficking. DiscussionTraining health care providers on caring for trafficked persons has the potential to improve practitioners’ knowledge about human trafficking and its health consequences, and to increase safe practices when responding in cases of trafficking. This study provides lessons for the design of training programs on human trafficking that aim to help health care providers identify and refer victims, and provide care for

  2. Consensus on management of metastatic colorectal cancer in Central America and the Caribbean: San José, Costa Rica, August 2016

    López, Roberto Ivan; Castro, Jenny Lissette; Cedeño, Heidy; Cisneros, Dagoberto; Corrales, Luis; González-Herrera, Ileana; Lima-Pérez, Mayté; Prestol, Rogelio; Salinas, Roberto; Soriano-García, Jorge Luis; T Zavala, Alejandra; Zetina, Luis Miguel; Zúñiga-Orlich, Carlos Eduardo

    2018-01-01

    Colorectal cancer (CRC) is the third most common cancer in men and the second most common in women worldwide. In Latin America and the Caribbean, it has a mortality of 56%. The median overall survival for patients with metastatic colorectal cancer (mCRC) is currently estimated as ~30 months, which has substantially improved through strategic changes in treatment and in the management of patients. As opposed to other metastatic cancers where first-line regimens are often determined, mCRC requires special attention because there is controversy in the possible combinations of the available drugs and the different periods of duration for each patient. Each combination must seek to be effective and to generate the minimum adverse effects as possible. Instead of giving the first-line regimen until the tumour progresses, treatment is often individualised. Furthermore, up to 60% of colorectal tumours are considered non-mutated or wild-type CRC. Not harbouring mutations in the RAS family of genes or mutations in the signalling pathways of the epidermal growth factor receptor causes a null response to anti-epidermal growth factor receptor antibody therapy, which implies even more complex considerations regarding its management. The primary objective of this consensus is to address the main scenarios of mCRC in order to warrant the most appropriate therapeutic intervention for these patients in the Central American and the Caribbean (CAC) region. This can lead to better clinical outcomes as well as quality of life for palliative patients. This document includes the formal expert consensus recommendations for scenarios of mutated and non-mutated mCRC, including synchronous or metachronous disease, management of mCRC with liver and lung metastasis, resectable, potentially resectable or non-resectable tumours and local in the CAC context. PMID:29636987

  3. Global and local genetic diversity at two microsatellite loci in Plasmodium vivax parasites from Asia, Africa and South America

    Schousboe, Mette L; Ranjitkar, Samir; Rajakaruna, Rupika S

    2014-01-01

    diversity are vital to the evaluation of drug and vaccine efficacy, tracking of P. vivax outbreaks, and assessing geographical differentiation between parasite populations. METHODS: The genetic diversity of eight P. vivax populations (n = 543) was investigated by using two microsatellites (MS), m1501 and m......3502, chosen because of their seven and eight base-pair (bp) repeat lengths, respectively. These were compared with published data of the same loci from six other P. vivax populations. RESULTS: In total, 1,440 P. vivax samples from 14 countries on three continents were compared. There was highest...... heterozygosity within Asian populations, where expected heterozygosity (He) was 0.92-0.98, and alleles with a high repeat number were more common. Pairwise FST revealed significant differentiation between most P. vivax populations, with the highest divergence found between Asian and South American populations...

  4. Effectiveness of a combination prevention strategy for HIV risk reduction with men who have sex with men in Central America: a mid-term evaluation.

    Firestone, Rebecca; Rivas, Jorge; Lungo, Susana; Cabrera, Alejandra; Ruether, Susan; Wheeler, Jennifer; Vu, Lung

    2014-12-04

    package. However, those reached are able to practice HIV prevention. Combination prevention is a promising approach in Central America, requiring expansion in coverage and intensity.

  5. Market regulation in Central America and Bit-Energy.CEL as tool for improving the self regulating forces for a liberalised market

    Reisinger, H.; Reuter, A.; Dulle, H.

    2002-01-01

    establishment of regional spot and contracts market comprising 6 Central American countries; 3. the introduction of a retail market, allowing auto generation for industrial consumers; 4. the introduction of a renewable and rural electrification support scheme; 5. the introduction of the stochastic planning tool Bit-Energy.CEL for making offers for the spot market less predictable and more flexible. The proposed paper will show more details on the history of market liberalisation in Central America, summarise ongoing activities for improving market efficiency and explain in more detail which role Bit-Energy.CEL plays in this process. (author)

  6. GLOBAL OPIOID EPIDEMIC: DOOMED TO FAIL WITHOUT GENETICALLY BASED PRECISION ADDICTION MEDICINE (PAM™): LESSONS LEARNED FROM AMERICA.

    Blum, Kenneth; Modestino, Edward J; Gondré-Lewis, Marjorie C; Neary, Jennifer; Siwicki, David; Hauser, Mary; Barh, Debmalya; Steinberg, Bruce; Badgaiyan, Rajendra D

    2017-01-01

    It is a reality that globally opioid deaths have soared for men and women of all social, economic status and age from heroin and fentanyl overdoses. Specifically, in the United States, deaths from narcotic overdoses have reached alarming metrics since 2010. In fact, the Fentanyl rise is driven by drug dealers who sell it as heroin or who use it to lace cocaine or to make illegal counterfeit prescription opioids. The President's Commission on the crisis has linked the death toll as equivalent to "September 11th every three weeks." In fact, The U.S. Centre for Disease Control (CDC) released data showing that opioid-related overdoses were up 15% in the first three quarters of 2016 compared to 2015. Various governmental organizations including NIDA, are actively seeking solutions. However, we argue that unless the scientific community embraces genetic addiction risk coupled with potential precision or personalized medicine to induce "dopamine homeostasis" it will fail. We now have evidence that a ten-gene and eleven single nucleotide polymorphism (SNP) panel predicts Addiction Severity Index (ASI) for both alcohol and drugs of abuse (e.g., Opioids). In a large multi-addiction centre study involving seven diverse treatment programs, the genetic addiction risk score (GARS ™ ) was shown to have a predictive relationship with ASI-MV derived alcohol (≥ seven alleles), and other drugs (≥ 4 alleles) severity risk scores. In a number of neuroimaging studies, we also display that in both animal (bench) and abstinent Chinese severe heroin-dependent patients (bedside), BOLD dopamine activation across the brain reward circuitry revealed increases in resting state functional connectivity as well volume connectivity. It is also known that published nutrigenomic (coupling gene polymorphisms with altered KB220z) studies reveal improved clinical outcomes related to obesity.

  7. Climate Impacts of Deforestation/Land-Use Changes in Central South America in the PRECIS Regional Climate Model: Mean Precipitation and Temperature Response to Present and Future Deforestation Scenarios

    Pablo O. Canziani; Gerardo Carbajal Benitez

    2012-01-01

    Deforestation/land-use changes are major drivers of regional climate change in central South America, impacting upon Amazonia and Gran Chaco ecoregions. Most experimental and modeling studies have focused on the resulting perturbations within Amazonia. Using the Regional Climate Model PRECIS, driven by ERA-40 reanalysis and ECHAM4 Baseline model for the period 1961–2000 (40-year runs), potential effects of deforestation/land-use changes in these and other neighboring ecoregions are evaluated....

  8. Phylogeography and Ecological Niche Modeling Reveal Reduced Genetic Diversity and Colonization Patterns of Skunk Cabbage (Symplocarpus foetidus; Araceae From Glacial Refugia in Eastern North America

    Seon-Hee Kim

    2018-05-01

    Full Text Available Alternating glacial and interglacial periods during the Quaternary have dramatically affected the distribution and population genetic structure of plant and animal species throughout the northern hemisphere. Surprisingly, little is known about the post-glacial recolonization history of wetland herbaceous perennials that are widely distributed in the understory of deciduous or mixed deciduous-evergreen forests in eastern North America. In this study, we investigated infraspecific variation among 32 populations of skunk cabbage, Symplocarpus foetidus, to test the hypothesis that the extant species diversity of skunk cabbage is the result of a post-glacial range expansion from southern refugia during the Quaternary Ice Age. A total of 4041 base pairs (bp of the chloroplast intergenic spacer region (cpDNA was sequenced from 485 individuals sampled from glaciated (18 populations, 275 individuals and unglaciated (14 populations, 210 individuals regions east and west of the Appalachian Mountains. Haplotype number, haplotype diversity, and nucleotide diversity were calculated, and genetic variation within and among populations was assessed by analysis of molecular variance (AMOVA. The geographic pattern of genetic differentiation was further investigated with a spatial analysis of molecular variance (SAMOVA. A total of eight haplotypes and three genetic groups (SAMOVA were recovered and a much higher haplotype number (eight haplotypes and haplotype diversity (0.7425 was observed in unglaciated compared to glaciated populations (five haplotypes, haplotype diversity = 0.6099. All haplotypes found in glaciated regions represented a subset of haplotypes found in unglaciated regions. Haplotypes of S. foetidus likely diverged during the Tertiary (mid-Miocene and late Pliocene, predating the last glacial maximum (LGM. Predictions based on ecological niche modeling (ENM suggested that there was considerably less suitable habitat for skunk cabbage during the LGM

  9. Invariability of Central Metabolic Flux Distribution in Shewanella oneidensis MR-1 Under Environmental or Genetic Perturbations

    Tang, Yinjie; Martin, Hector Garcia; Deutschbauer, Adam; Feng, Xueyang; Huang, Rick; Llora, Xavier; Arkin, Adam; Keasling, Jay D.

    2009-04-21

    An environmentally important bacterium with versatile respiration, Shewanella oneidensis MR-1, displayed significantly different growth rates under three culture conditions: minimal medium (doubling time {approx} 3 hrs), salt stressed minimal medium (doubling time {approx} 6 hrs), and minimal medium with amino acid supplementation (doubling time {approx}1.5 hrs). {sup 13}C-based metabolic flux analysis indicated that fluxes of central metabolic reactions remained relatively constant under the three growth conditions, which is in stark contrast to the reported significant changes in the transcript and metabolite profiles under various growth conditions. Furthermore, ten transposon mutants of S. oneidensis MR-1 were randomly chosen from a transposon library and their flux distributions through central metabolic pathways were revealed to be identical, even though such mutational processes altered the secondary metabolism, for example, glycine and C1 (5,10-Me-THF) metabolism.

  10. Differential neural representation of oral ethanol by central taste-sensitive neurons in ethanol-preferring and genetically heterogeneous rats.

    Lemon, Christian H; Wilson, David M; Brasser, Susan M

    2011-12-01

    In randomly bred rats, orally applied ethanol stimulates neural substrates for appetitive sweet taste. To study associations between ethanol's oral sensory characteristics and genetically mediated ethanol preference, we made electrophysiological recordings of oral responses (spike density) by taste-sensitive nucleus tractus solitarii neurons in anesthetized selectively bred ethanol-preferring (P) rats and their genetically heterogeneous Wistar (W) control strain. Stimuli (25 total) included ethanol [3%, 5%, 10%, 15%, 25%, and 40% (vol/vol)], a sucrose series (0.01, 0.03, 0.1, 0.3, 0.5, and 1 M), and other sweet, salt, acidic, and bitter stimuli; 50 P and 39 W neurons were sampled. k-means clustering applied to the sucrose response series identified cells showing high (S(1)) or relatively low (S(0)) sensitivity to sucrose. A three-way factorial analysis revealed that activity to ethanol was influenced by a neuron's sensitivity to sucrose, ethanol concentration, and rat line (P = 0.01). Ethanol produced concentration-dependent responses in S(1) neurons that were larger than those in S(0) cells. Although responses to ethanol by S(1) cells did not differ between lines, neuronal firing rates to ethanol in S(0) cells increased across concentration only in P rats. Correlation and multivariate analyses revealed that ethanol evoked responses in W neurons that were strongly and selectively associated with activity to sweet stimuli, whereas responses to ethanol by P neurons were not easily associated with activity to representative sweet, sodium salt, acidic, or bitter stimuli. These findings show differential central neural representation of oral ethanol between genetically heterogeneous rats and P rats genetically selected to prefer alcohol.

  11. Identification of genetic mutations in patients with familial central diabetes insipidus

    Francisco, Ângela Sofia Fernandes Alves

    2012-01-01

    Diabetes insipidus (DI) is associated with defects that involve the secretion and the action of hormone arginine vasopressin (AVP) resulting in the excretion of abnormally large volumes of diluted urine. The most common defect that results in disease development is the deficient secretion of the hormone AVP and the disease is referred to as central or neurohypophyseal DI. The AVP hormone is synthesized in magnocellular neurons, that originate in the supraoptic and paraventricular nuclei of th...

  12. Revalidation and genetic characterization of new members of Group C (Orthobunyavirus genus, Peribunyaviridae family) isolated in the Americas.

    Nunes, Márcio Roberto Teixeira; de Souza, William Marciel; Acrani, Gustavo Olszanski; Cardoso, Jedson Ferreira; da Silva, Sandro Patroca; Badra, Soraya Jabur; Figueiredo, Luiz Tadeu Moraes; Vasconcelos, Pedro Fernando da Costa

    2018-01-01

    Group C serogroup includes members of the Orthobunyavirus genus (family Peribunyaviridae) and comprises 15 arboviruses that can be associated with febrile illness in humans. Although previous studies described the genome characterization of Group C orthobunyavirus, there is a gap in genomic information about the other viruses in this group. Therefore, in this study, complete genomes of members of Group C serogroup were sequenced or re-sequenced and used for genetic characterization, as well as to understand their phylogenetic and evolutionary aspects. Thus, our study reported the genomes of three new members in Group C virus (Apeu strain BeAn848, Itaqui strain BeAn12797 and Nepuyo strain BeAn10709), as well as re-sequencing of original strains of five members: Caraparu (strain BeAn3994), Madrid (strain BT4075), Murucutu (strain BeAn974), Oriboca (strain BeAn17), and Marituba (strain BeAn15). These viruses presented a typical genomic organization related to members of the Orthobunyavirus genus. Interestingly, all viruses of this serogroup showed an open reading frame (ORF) that encodes the putative nonstructural NSs protein that precedes the nucleoprotein ORF, an unprecedented fact in Group C virus. Also, we confirmed the presence of natural reassortment events. This study expands the genomic information of Group C viruses, as well as revalidates the genomic organization of viruses that were previously reported.

  13. Clinical and molecular genetic features of Hb H and AE Bart's diseases in central Thai children.

    Traivaree, Chanchai; Boonyawat, Boonchai; Monsereenusorn, Chalinee; Rujkijyanont, Piya; Photia, Apichat

    2018-01-01

    α-Thalassemia, one of the major thalassemia types in Thailand, is caused by either deletion or non-deletional mutation of one or both α-globin genes. Inactivation of three α-globin genes causes hemoglobin H (Hb H) disease, and the combination of Hb H disease with heterozygous hemoglobin E (Hb E) results in AE Bart's disease. This study aimed to characterize the clinical and hematological manifestations of 76 pediatric patients with Hb H and AE Bart's diseases treated at Phramongkutklao Hospital, a tertiary care center for thalassemia patients in central Thailand. Seventy-six unrelated pediatric patients, 58 patients with Hb H disease and 18 patients with AE Bart's disease, were enrolled in this study. Their clinical presentations, transfusion requirement, laboratory findings, and mutation analysis were retrospectively reviewed and analyzed. A total of 76 pediatric patients with Hb H and AE Bart's diseases who mainly lived in central Thailand were included in this study. The clinical severities of patients with non-deletional mutations were more severe than those with deletional mutations. Eighty-six percent of patients with non-deletional AE Bart's disease required more blood transfusion compared to 12.5% of patients with deletional AE Bart's disease. Non-deletional AE Bart's disease also had a history of urgent blood transfusion with the average of 6±0.9 times compared to 1±0.3 times in patients with deletional Hb H disease. The difference was statistically significant. This study revealed the differences in clinical spectrum between patients with Hb H disease and those with AE Bart's disease in central Thailand. The differentiation of α-thalassemia is essential for appropriate management of patients. The molecular diagnosis is useful for diagnostic confirmation and genotype-phenotype correlation.

  14. Unnatural base pair systems toward the expansion of the genetic alphabet in the central dogma.

    Hirao, Ichiro; Kimoto, Michiko

    2012-01-01

    Toward the expansion of the genetic alphabet of DNA, several artificial third base pairs (unnatural base pairs) have been created. Synthetic DNAs containing the unnatural base pairs can be amplified faithfully by PCR, along with the natural A-T and G-C pairs, and transcribed into RNA. The unnatural base pair systems now have high potential to open the door to next generation biotechnology. The creation of unnatural base pairs is a consequence of repeating "proof of concept" experiments. In the process, initially designed base pairs were modified to address their weak points. Some of them were artificially evolved to ones with higher efficiency and selectivity in polymerase reactions, while others were eliminated from the analysis. Here, we describe the process of unnatural base pair development, as well as the tests of their applications.

  15. Genetic Variations in Bionomics of (Diptera: Culicidae Mosquito Population in Minna, North Central Nigeria

    Azubuike C. Ukubuiwe

    2016-01-01

    Full Text Available The need to have an improved knowledge on the bioecology of Culex quinquefasciatus , a prerequisite in the development of cost-effective control strategies, has informed the present preliminary investigation to put in better perspective variations that exist in the egg rafts of the species. Freshly laid egg rafts were collected and incubated at ambient temperature in well-labeled plastic trays. The results showed overall inconsistency in all indices monitored for the egg rafts. Generally, survivorship was high for the species. All immature stage and adult parameters measured varied significantly among the egg rafts and between/within sexes of the species. Therefore, this study suggests the presence of inherent variation in the bionomics of egg rafts of C. quinquefasciatus , probably influenced by the environment and hence underscores the need for additional studies to further elucidate the roles of genetics and environment in vectorial competence of the species, in order to develop robust sustainable mosquito vector control protocols.

  16. Genetic diversity in the block 2 region of the merozoite surface protein-1 of Plasmodium falciparum in central India

    Bharti Praveen K

    2012-03-01

    Full Text Available Abstract Background Malaria continues to be a significant health problem in India. Several of the intended Plasmodium falciparum vaccine candidate antigens are highly polymorphic. The genetic diversity of P. falciparum merozoite surface protein-1 (MSP-1 has been extensively studied from various parts of the world. However, limited data are available from India. The aim of the present study was a molecular characterization of block 2 region of MSP-1 gene from the tribal-dominated, forested region of Madhya Pradesh. Methods DNA sequencing analysis was carried out in 71 field isolates collected between July 2005 to November 2005 and in 98 field isolates collected from July 2009 to December 2009. Alleles identified by DNA sequencing were aligned with the strain 3D7 and polymorphism analysis was done by using Edit Sequence tool (DNASTAR. Results The malaria positivity was 26% in 2005, which rose to 29% in 2009 and P. falciparum prevalence was also increased from 72% in 2005 to 81% in 2009. The overall allelic prevalence was higher in K1 (51% followed by MAD20 (28% and RO33 (21% in 2005 while in 2009, RO33 was highest (40% followed by K1 (36% and MAD20 (24%. Conclusions The present study reports extensive genetic variations and dynamic evolution of block 2 region of MSP-1 in central India. Characterization of antigenic diversity in vaccine candidate antigens are valuable for future vaccine trials as well as understanding the population dynamics of P. falciparum parasites in this area.

  17. Genetic markers for inherited thrombophilia are associated with fetal growth retardation in the population of Central Russia.

    Reshetnikov, Evgeny; Zarudskaya, Oksana; Polonikov, Alexey; Bushueva, Olga; Orlova, Valentina; Krikun, Evgeny; Dvornyk, Volodymyr; Churnosov, Mikhail

    2017-07-01

    The aim of this study was to examine the role of hereditary thrombophilia in the development of fetal growth retardation (FGR) in the population of Central Russia. The case-control study sample included 497 women in the third trimester of pregnancy recruited during 2009-2013. The participants were enrolled into two groups: patients with FGR (n = 250) and controls without FGR (n = 247). The participants were genotyped for four genetic markers of hereditary thrombophilia: factor V Leiden (G > A FV, rs6025), prothrombin (G > A FII, rs1799963), factor VII (G > A FVII, rs6046), and fibrinogen (G > A FI, rs1800790). The genetic factors for an increased risk of FGR were allele G of rs6046 (odds ratio [OR] = 2.34) and genotype GG of rs6046 (OR = 2.64), whereas genotype GA of rs6046 had the protective value (OR = 0.42). A combination of alleles G of rs1799963, A of rs6046, and G of rs1800790 (OR = 0.31) reduces the risk of FGR. Polymorphism rs6046 of the FVII gene is associated with the development of FGR. © 2017 Japan Society of Obstetrics and Gynecology.

  18. Genetic variation at the ApoB 3' HVR minisatellite locus in the Mbenzele Pygmies from the Central African Republic.

    Destro-Bisol, Giovanni; Belledi, Michele; Capelli, Cristian; Maviglia, Riccardo; Spedini, Gabriella

    2000-09-01

    This study analyzes the polymorphic minisatellite ApoB 3' HVR in the Mbenzele Pygmies from the Central African Republic. A total of 14 alleles was observed, with frequencies ranging from 0.020 (19, 21, 27, and 45 repeat unit alleles) to 0.210 (37 repeat unit allele). Departure from Hardy-Weinberg equilibrium was not statistically significant. The estimated heterozygosity was 0.874 +/- 0.016. Taking data from the literature into consideration, the results support the hypothesis that the Africans are different from non-Africans due to greater ApoB 3' HVR genetic diversity and a unimodal profile of ApoB 3' HVR allele frequency distribution. Interpopulational relationships were also analyzed using an F(ST) based genetic distance. The results highlight the similarity between the Mbenzele Pygmies and Bantu-speaking groups (Ewondo and Zulu), and the divergence between the Mbenzele and San, the two groups which are often considered to be the most direct descendants of proto-Africans. Am. J. Hum. Biol. 12:588-592, 2000. Copyright 2000 Wiley-Liss, Inc.

  19. Genetic analysis of central carbon metabolism unveils an amino acid substitution that alters maize NAD-dependent isocitrate dehydrogenase activity.

    Nengyi Zhang

    2010-04-01

    Full Text Available Central carbon metabolism (CCM is a fundamental component of life. The participating genes and enzymes are thought to be structurally and functionally conserved across and within species. Association mapping utilizes a rich history of mutation and recombination to achieve high resolution mapping. Therefore, applying association mapping in maize (Zea mays ssp. mays, the most diverse model crop species, to study the genetics of CCM is a particularly attractive system.We used a maize diversity panel to test the CCM functional conservation. We found heritable variation in enzyme activity for every enzyme tested. One of these enzymes was the NAD-dependent isocitrate dehydrogenase (IDH, E.C. 1.1.1.41, in which we identified a novel amino-acid substitution in a phylogenetically conserved site. Using candidate gene association mapping, we identified that this non-synonymous polymorphism was associated with IDH activity variation. The proposed mechanism for the IDH activity variation includes additional components regulating protein level. With the comparison of sequences from maize and teosinte (Zea mays ssp. Parviglumis, the maize wild ancestor, we found that some CCM genes had also been targeted for selection during maize domestication.Our results demonstrate the efficacy of association mapping for dissecting natural variation in primary metabolic pathways. The considerable genetic diversity observed in maize CCM genes underlies heritable phenotypic variation in enzyme activities and can be useful to identify putative functional sites.

  20. Genetic variation and evolution of Polaskia chichipe (Cactaceae) under domestication in the Tehuacán Valley, central Mexico.

    Otero-Arnaiz, Adriana; Casas, Alejandro; Hamrick, James L; Cruse-Sanders, Jennifer

    2005-05-01

    Polaskia chichipe is a columnar cactus under artificial selection in central Mexico because of its edible fruits. Our study explored the effect of human manipulation on levels and distribution of genetic variation in wild, silviculturally managed and cultivated sympatric populations. Total genetic variation, estimated in nine populations with five microsatellite loci, was H(T) = 0.658 +/- 0.026 SE, which was mainly distributed within populations (H(S) = 0.646) with low differentiation among them (F(ST) = 0.015). Fixation index (F(IS)) in all populations was positive, indicating a deficit of heterozygous individuals with respect to Hardy-Weinberg expectations. When populations were pooled by management type, the highest expected heterozygosity (H(E) = 0.631 +/- 0.031 SE) and the lowest fixation index (F(IS) = 0.07) were observed in wild populations, followed by cultivated populations (H(E) = 0.56 +/- 0.03 SE, F(IS) = 0.14), whereas the lowest variation was found in silviculturally managed populations (H(E) = 0.51 +/- 0.05 SE, F(IS) = 0.17). Low differentiation among populations under different management types (F(ST) 0.005, P < 0.04) was observed. A pattern of migration among neighbouring populations, suggested from isolation by distance (r2 = 0.314, P < 0.01), may have contributed to homogenizing populations and counteracting the effects of artificial selection. P. chichipe, used and managed for at least 700 generations, shows morphological differentiation, changes in breeding system and seed germination patterns associated with human management, with only slight genetic differences detected by neutral markers.

  1. A novel educational strategy targeting health care workers in underserved communities in Central America to integrate HIV into primary medical care.

    Tamara Flys

    Full Text Available BACKGROUND: Current educational strategies to integrate HIV care into primary medical care in Central America have traditionally targeted managers or higher-level officials, rather than local health care workers (HCWs. We developed a complementary online and on-site interactive training program to reach local HCWs at the primary care level in underserved communities. METHODS: The training program targeted physicians, nurses, and community HCWs with limited access to traditional onsite training in Panama, Nicaragua, Dominican Republic, and Guatemala. The curriculum focused on principles of HIV care and health systems using a tutor-supported blended educational approach of an 8-week online component, a weeklong on-site problem-solving workshop, and individualized project-based interventions. RESULTS: Of 258 initially active participants, 225 (225/258=87.2% successfully completed the online component and the top 200 were invited to the on-site workshop. Of those, 170 (170/200=85% attended the on-site workshop. In total, 142 completed all three components, including the project phase. Quantitative and qualitative evaluation instruments included knowledge assessments, reflexive essays, and acceptability surveys. The mean pre and post-essay scores demonstrating understanding of social determinants, health system organization, and integration of HIV services were 70% and 87.5%, respectively, with an increase in knowledge of 17.2% (p<0.001. The mean pre- and post-test scores evaluating clinical knowledge were 70.9% and 90.3%, respectively, with an increase in knowledge of 19.4% (p<0.001. A survey of Likert scale and open-ended questions demonstrated overwhelming participant satisfaction with course content, structure, and effectiveness in improving their HIV-related knowledge and skills. CONCLUSION: This innovative curriculum utilized technology to target HCWs with limited access to educational resources. Participants benefited from technical skills

  2. Discovery of new Ohbayashinema spp. (Nematoda: Heligmosomoidea) in Ochotona princeps and Ochotona cansus (Lagomorpha: Ochotonidae) from western North America and Central Asia, with considerations of historical biogeography.

    Durette-Desset, M-C; Galbreath, K E; Hoberg, E P

    2010-06-01

    Three new species of Ohbayashinema (Nematoda, Heligmosomoidea) are described from localities in western North America and central Asia. Two of these species, Ohbayashinema nearctica n. sp. and Ohbayashinema aspeira n. sp., are parasitic in American pika, Ochotona princeps. Ohbayashinema nearctica is differentiated from the 5 known species of the genus parasitic in Ochotonidae from the Old World by very long spicules and an oblique axis of orientation for the ridges composing the synlophe. Ohbayashinema aspeira, described only from females, is similar to Oh. nearctica based on the number of cuticular ridges at the mid-body. It is mainly differentiated by an uncoiled anterior extremity and by near equal dimensions of the vestibule and the uterus. The third species, Ohbayashinema patriciae n. sp., is parasitic in Gansu pika, Ochotona cansus , from China. It is similar to Ohbayashinema erbaevae parasitic in Ochotona dauurica from Buriatia and Ohbayashinema ochotoni in Ochotona macrotis from Nepal, based on the length of the spicules and the ratio of spicule length to body length. It differs from the former species by possessing a smaller number of cuticular ridges and in the comparative length of the vestibule and infundibulum. Related to Oh. ochotoni by an identical number of cuticular ridges at the mid-body, it differs from this species in having smaller ridges in the dorsal rather than ventral field and in the dimensions of the dorsal ray where rays 9 are less than rays 10. Species of Ohbayashinema appear to be host-specific among the Ochotonidae but had not been previously reported in pikas from the Nearctic. Although much remains to be demonstrated about the diversity for helminths in pikas, it is apparent that factors associated with the assembly and structure of parasite faunas have been complex, involving episodic processes for geographic and host colonization along with coevolutionary mechanisms. Understanding the historical factors, particularly climate

  3. Increased prevalence of Plasmodium falciparum malaria in Honduras, Central America Aumento de la prevalencia de malaria por Plasmodium falciparum en Honduras, Centroamerica

    Carol J. Palmer

    1998-07-01

    Full Text Available We report on our investigation of a malaria outbreak in Honduras, Central America, in January 1997. We tested 202 patients with fever and chills using thin and thick blood film microscopy. Sixteen patients lived in the city and the rest lived in rural areas. A total of 95 samples (47% were positive for malaria parasites. Seventy-nine percent (63/80 of the rural patients were infected with Plasmodium vivax and 21% (17/80 were infected with P. falciparum. In the urban area, all 15 infected patients had P. vivax malaria and none showed evidence of P. falciparum. Since previous reports indicate that falciparum malaria accounts for only 2% of the overall malaria infections in Honduras, the results reported here suggest that there is a dramatic increase in falciparum malaria in the area of Honduras investigated in this study.Notificamos los resultados de un estudio de un brote de malaria que se produjo en Honduras, Centroamérica, en enero de 1997. Sometimos a examen microscópico frotis delgados y frotis gruesos de la sangre de 202 pacientes con fiebre y escalofríos. Dieciséis pacientes eran habitantes de la zona urbana y el resto de la zona rural. Un total de 95 especímenes (47% fueron positivos a parásitos de la malaria. Setenta y ocho por ciento (62/80 de los pacientes del área rural estaban infestados con Plasmodium vivax y 22% (17/80 con P. falciparum. En la zona urbana, todos los 15 pacientes que estaban infestados tenían P. vivax y en ninguno se detectó P. falciparum. Ya que según informes previos la malaria de tipo falciparum representa solamente 2% de todos los casos de malaria en Honduras, nuestros resultados sugieren que hay un gran incremento del número de casos de malaria falciparum en la zona de Honduras en que se llevó a cabo esta investigación.

  4. Postglacial recolonization in a cold climate specialist in western Europe: patterns of genetic diversity in the adder (Vipera berus) support the central-marginal hypothesis.

    Ursenbacher, Sylvain; Guillon, Michaël; Cubizolle, Hervé; Dupoué, Andréaz; Blouin-Demers, Gabriel; Lourdais, Olivier

    2015-07-01

    Understanding the impact of postglacial recolonization on genetic diversity is essential in explaining current patterns of genetic variation. The central-marginal hypothesis (CMH) predicts a reduction in genetic diversity from the core of the distribution to peripheral populations, as well as reduced connectivity between peripheral populations. While the CMH has received considerable empirical support, its broad applicability is still debated and alternative hypotheses predict different spatial patterns of genetic diversity. Using microsatellite markers, we analysed the genetic diversity of the adder (Vipera berus) in western Europe to reconstruct postglacial recolonization. Approximate Bayesian Computation (ABC) analyses suggested a postglacial recolonization from two routes: a western route from the Atlantic Coast up to Belgium and a central route from the Massif Central to the Alps. This cold-adapted species likely used two isolated glacial refugia in southern France, in permafrost-free areas during the last glacial maximum. Adder populations further from putative glacial refugia had lower genetic diversity and reduced connectivity; therefore, our results support the predictions of the CMH. Our study also illustrates the utility of highly variable nuclear markers, such as microsatellites, and ABC to test competing recolonization hypotheses. © 2015 John Wiley & Sons Ltd.

  5. Emergence of quinolone resistance among extended-spectrum beta-lactamase-producing Enterobacteriaceae in the Central African Republic: genetic characterization

    Frank Thierry

    2011-08-01

    Full Text Available Abstract Background Cross-resistance to quinolones and beta-lactams is frequent in Enterobacteriaceae, due to the wide use of these antibiotics clinically and in the food industry. Prescription of one of these categories of antibiotic may consequently select for bacteria resistant to both categories. Genetic mechanisms of resistance may be secondary to a chromosomal mutation located in quinolone resistance determining region of DNA gyrase or topoisomerase IV or to a plasmid acquisition. The insertion sequence ISCR1 is often associated with qnr and may favour its dissemination in Gram-negative bacteria. The aim of this study was to determine the genetic mechanism of quinolone resistance among extended-spectrum beta-lactamase-producing Enterobacteriaceae strains in the Central African Republic. Findings Among seventeen ESBL-producing Enterobacteriaceae isolated from urine, pus or stool between January 2003 and October 2005 in the Central African Republic, nine were resistant to ciprofloxacin (seven from community patients and two from hospitalized patients. The ESBL were previously characterized as CTX-M-15 and SHV-12. Susceptibility to nalidixic acid, norfloxacin and ciprofloxacin, and the minimal inhibitory concentrations of these drugs were determined by disc diffusion and agar dilution methods, respectively. The presence of plasmid-borne ISCR1-qnrA region was determined by PCR and amplicons, if any, were sent for sequencing. Quinolone resistance determining region of DNA gyrase gyrA gene was amplified by PCR and then sequenced for mutation characterization. We found that all CTX-M-producing strains were resistant to the tested quinolones. All the isolates had the same nucleotide mutation at codon 83 of gyrA. Two Escherichia coli strains with the highest MICs were shown to harbour an ISCR1-qnrA1 sequence. This genetic association might favour dissemination of resistance to quinolone and perhaps other antibiotics among Enterobacteriaceae

  6. Genetic diversity of Hepatozoon spp. in coyotes from the south-central United States.

    Starkey, Lindsay A; Panciera, Roger J; Paras, Kelsey; Allen, Kelly E; Reiskind, Michael H; Reichard, Mason V; Johnson, Eileen M; Little, Susan E

    2013-04-01

    To better define the strains and species of Hepatozoon that infect coyotes in the south-central United States, whole blood and muscle samples were collected from 44 coyotes from 6 locations in Oklahoma and Texas. Samples were evaluated by a nested polymerase chain reaction (PCR) using primers amplifying a variable region of the apicomplexan 18S rRNA gene as well as histopathology (muscle only) for presence of tissue cysts. Hepatozoon spp. infections were identified in 79.5% (35/44) of coyotes tested including 27 of 44 (61.4%) whole blood samples and 17 of 44 (38.6%) muscle samples tested by PCR and 23 of 44 (52.3%) muscle samples evaluated by histological examination. Analysis revealed 19 distinct sequences comprising 3 major clusters of Hepatozoon spp., i.e., 1 most closely related to Hepatozoon americanum, another most closely related to Hepatozoon canis , and the third an intermediate between the 2 groups. The diversity of Hepatozoon spp. in wild canids appears greater than previously recognized and warrants further investigation.

  7. Genetic and stratigraphic significance of the Upper Devonian Frasnian Z Marker, west-central Alberta

    Wendte, J. [Geological Survey of Canada, Calgary, AB (Canada); Stoakes, F. [Stoakes Consulting Group Ltd., Calgary, AB (Canada); Bosman, M. [Canadian Hunter Exploration Ltd., Calgary, AB (Canada); Bernstein, L. [Talisman Energy Inc., Calgary, AB (Canada)

    1995-12-01

    The stratigraphic model from the west-central Alberta basin was provided. It defined the Z Marker as a distinctive and widespread wireline log marker within the thick Frasnian Ireton shale basin succession. The marker represents an interval of condensed sedimentation and corresponds to an abrupt change from a calcareous signature below to an argillaceous character above. Toward the shelf, in the West Pembina area, the Z Marker correlates to a level within a conformable succession of nodular lime wackestones and corresponds to the base of a depositional cycle near the middle of the Lobstick member of the Nisku Formation. Further shelfward, the Z Marker continues as a well-defined log marker until the Nisku shelf margin. The stratigraphic significance of the Z Marker in delineating various oil bearing formations in Alberta were explained in great detail. The correct recognition and correlation of this marker was claimed to permit an understanding of basin evolution beyond that discernable from the existing lithostratigraphic nomenclature alone. 17 refs., 13 figs.

  8. Phylogeography, risk factors and genetic history of hepatitis C virus in Gabon, central Africa.

    Richard Njouom

    Full Text Available BACKGROUND: The epidemiological and molecular characteristics of hepatitis C virus (HCV infection in the general population have been poorly investigated in Africa. The aim of this study was to determine the prevalence, genotype distribution and epidemic history of HCV in the Gabonese general population. METHODS/PRINCIPAL FINDINGS: A total of 4042 sera collected from adults in 220 villages in all nine administrative areas of the country were screened for antibodies to HCV. HCV NS5B region sequencing was performed for molecular characterization and population genetic analyses. Of 4042 tested sera, 455 (11.2% were positive. The seroprevalence of HCV varied significantly by administrative area, with the highest rate in Ogooué-Lolo province (20.4% and the lowest in Ogooué-Maritine province (3.7%. History of parenteral injections, past hospital admission and age over 55 years were independent risk factors for HCV infection (p<0.0001. Phylogenetic analyses showed that 91.9% of the strains were genotype 4 (HCV-4, 5.7% genotype 1 and 2.2% genotype 2. HCV-4 strains were highly heterogeneous, with more than eight subtypes; subtype 4e predominated (57.3%. Coalescence analyses indicated that subtype 4e was the oldest, with an estimated most recent common ancestor of 1702 [95% CI, 1418-1884]. The epidemic profile indicated that it spread exponentially during the first part of the 20th century, probably by iatrogenic transmission. CONCLUSIONS/SIGNIFICANCE: These results confirm the endemicity of HCV subtype 4e in Gabon and show that its spread is due to a cohort effect, with previous, possibly iatrogenic events. More extensive epidemiological studies are needed to better characterize the route of transmission and the dissemination of HCV in Gabon.

  9. Genetic Separation of Listeria monocytogenes Causing Central Nervous System Infections in Animals

    Lisandra Aguilar-Bultet

    2018-02-01

    Full Text Available Listeria monocytogenes is a foodborne pathogen that causes abortion, septicemia, gastroenteritis and central nervous system (CNS infections in ruminants and humans. L. monocytogenes strains mainly belong to two distinct phylogenetic groups, named lineages I and II. In general, clinical cases in humans and animals, in particular CNS infections, are caused by lineage I strains, while most of the environmental and food strains belong to lineage II. Little is known about why lineage I is more virulent than lineage II, even though various molecular factors and mechanisms associated with pathogenesis are known. In this study, we have used a variety of whole genome sequence analyses and comparative genomic tools in order to find characteristics that distinguish lineage I from lineage II strains and CNS infection strains from non-CNS strains. We analyzed 225 strains and identified single nucleotide variants between lineages I and II, as well as differences in the gene content. Using a novel approach based on Reads Per Kilobase per Million Mapped (RPKM, we identified 167 genes predominantly absent in lineage II but present in lineage I. These genes are mostly encoding for membrane-associated proteins. Additionally, we found 77 genes that are largely absent in the non-CNS associated strains, while 39 genes are especially lacking in our defined “non-clinical” group. Based on the RPKM analysis and the metadata linked to the L. monocytogenes strains, we identified 6 genes potentially associated with CNS cases, which include a transcriptional regulator, an ABC transporter and a non-coding RNA. Although there is not a clear separation between pathogenic and non-pathogenic strains based on phylogenetic lineages, the presence of the genes identified in our study reveals potential pathogenesis traits in ruminant L. monocytogenes strains. Ultimately, the differences that we have found in our study will help steer future studies in understanding the virulence

  10. Genetic Variation of Giardia lamblia Isolates from Food-handlers in Kashan, Central Iran

    Hossein HOOSHYAR

    2017-02-01

    Full Text Available Background: Based on genotyping study of human isolates of Giardia lamblia; humans are mainly infected by two assemblages A and B. The present study was carried out to determine the sub-assemblages of G. lamblia isolated from food handlers referred to Kashan health centers, central Iran, 2015.Methods: In this cross-sectional study, 3653 stool samples collected from food-handlers that annually refer to health center for getting a health certification and examined microscopically for G. lamblia cyst. Totally, 44 isolates were selected from 47 Giardia positive samples. Cysts were partially purified by the sucrose density gradient method. After freeze-thaw cycles, genomic DNA was extracted using QIAamp Stool Mini kit. A single step PCR-RFLP method was used to amplify a 458bp fragment at the glutamate dehydrogenase (gdh locus, restriction enzymes BspLI and RsaI were used for distinguish between genotypes A and B and their subgroups.Results: Of 44 isolates, 24(54.5% were sub-assemblage AII, 9(20.5% group B including 7(15.9% BIII and 2(4.6% BIV sub-assemblage and 11(25% isolates showed a mixed pattern of AII and B. Sub-assemblage AI was not detected in this study.Conclusion: The higher rate of sub-assemblage AII demonstrated an anthroponotic origin of the infection so infected food-handlers could directly transmit this protozoan to consumers via contaminated food and water. For finding of pattern of transmission and distribution of Giardia assemblages and sub-assemblage, more studies in human and animal population in different regions are necessary.

  11. Genetic Separation of Listeria monocytogenes Causing Central Nervous System Infections in Animals

    Aguilar-Bultet, Lisandra; Nicholson, Pamela; Rychener, Lorenz; Dreyer, Margaux; Gözel, Bulent; Origgi, Francesco C.; Oevermann, Anna; Frey, Joachim; Falquet, Laurent

    2018-01-01

    Listeria monocytogenes is a foodborne pathogen that causes abortion, septicemia, gastroenteritis and central nervous system (CNS) infections in ruminants and humans. L. monocytogenes strains mainly belong to two distinct phylogenetic groups, named lineages I and II. In general, clinical cases in humans and animals, in particular CNS infections, are caused by lineage I strains, while most of the environmental and food strains belong to lineage II. Little is known about why lineage I is more virulent than lineage II, even though various molecular factors and mechanisms associated with pathogenesis are known. In this study, we have used a variety of whole genome sequence analyses and comparative genomic tools in order to find characteristics that distinguish lineage I from lineage II strains and CNS infection strains from non-CNS strains. We analyzed 225 strains and identified single nucleotide variants between lineages I and II, as well as differences in the gene content. Using a novel approach based on Reads Per Kilobase per Million Mapped (RPKM), we identified 167 genes predominantly absent in lineage II but present in lineage I. These genes are mostly encoding for membrane-associated proteins. Additionally, we found 77 genes that are largely absent in the non-CNS associated strains, while 39 genes are especially lacking in our defined “non-clinical” group. Based on the RPKM analysis and the metadata linked to the L. monocytogenes strains, we identified 6 genes potentially associated with CNS cases, which include a transcriptional regulator, an ABC transporter and a non-coding RNA. Although there is not a clear separation between pathogenic and non-pathogenic strains based on phylogenetic lineages, the presence of the genes identified in our study reveals potential pathogenesis traits in ruminant L. monocytogenes strains. Ultimately, the differences that we have found in our study will help steer future studies in understanding the virulence mechanisms of the

  12. Genetics

    Hubitschek, H.E.

    1975-01-01

    Progress is reported on the following research projects: genetic effects of high LET radiations; genetic regulation, alteration, and repair; chromosome replication and the division cycle of Escherichia coli; effects of radioisotope decay in the DNA of microorganisms; initiation and termination of DNA replication in Bacillus subtilis; mutagenesis in mouse myeloma cells; lethal and mutagenic effects of near-uv radiation; effect of 8-methoxypsoralen on photodynamic lethality and mutagenicity in Escherichia coli; DNA repair of the lethal effects of far-uv; and near uv irradiation of bacterial cells

  13. Population genetics of IFITM3 in Portugal and Central Africa reveals a potential modifier of influenza severity.

    David, Susana; Correia, Vanessa; Antunes, Liliana; Faria, Ricardo; Ferrão, José; Faustino, Paula; Nunes, Baltazar; Maltez, Fernando; Lavinha, João; Rebelo de Andrade, Helena

    2018-03-01

    Influenza epidemics are a serious global public health and economic problem. The IFITM3 allele (rs12252-C) was suggested as a population-based genetic risk factor for severe influenza virus infection by A(H1N1)pdm09. We analyzed the population genetics of IFITM3 variants in the Portuguese general population (n = 200) and Central Africans (largely Angolan) (n = 148) as well as its association to influenza severity in Portuguese patients (n = 41). Seven SNPs, within the 352 bp IFITM3 amplicon around rs12252, were identified. SNP distributions in the Portuguese appeared at an intermediate level between the Africans and other Europeans. According to HapMap, rs34481144 belongs to the same linkage disequilibrium (LD) block as rs12252 and is in strong LD with rs6421983. A negative association with severe relative to mild disease was observed for allele rs34481144-A, indicating a protective effect under the dominant model. Moreover, haplotype Hap4 with rs34481144-A, not including rs12252-C, was significantly associated to mild influenza. Conversely, although with borderline significance, haplotype Hap1 with rs34481144-G, not including rs12252-C, was associated to severe disease. Moreover, in comparison to the general Portuguese population, statistical significant differences in the frequencies of the protective allele rs34481144-A in the severe disease group, the deleterious Hap1 in the mild disease group, and the protective Hap4 in the severe disease group were observed. The population attributable risk (PAR) for the targeted rs34481144 allele or genotype was of 55.91 and 64.44% in the general population and the mildly infected individuals, respectively. Implication of these variants in disease phenotype needs further validation, namely through functional analysis as is discussed.

  14. Late Cretaceous-recent tectonic assembly of diverse crustal blocks in Central America, the Nicaraguan Rise, the Colombian Basin and northern South America as seen on a 1600-km-long, geologic and structural transect

    Sanchez, J.; Mann, P.

    2015-12-01

    We have constructed a 1600-km-long transect from northern Honduras to northern Colombia that crosses northeastward-striking crustal blocks using a combination of offshore seismic data, gravity and magnetic data, well subsidence information, nearby outcrop information, and results from previous thermochronological, geochronological, geochemical and paleostress studies. The transect defines three major crustal and structural provinces: 1) Precambrian-Paleozoic, Chortis continental block whose northern edge is defined by the North America-Caribbean plate boundary. Events in this ~20-25-km-thick province include two major unconformities at the top of the Cretaceous and Eocene, associated southeast-dipping thrust faults related to collision of the Great Arc of the Caribbean (GAC) and Caribbean Large Igneous Province (CLIP) with the Chortis continental block. A third event is Eocene to recent subsidence and transtensional basins formed during the opening of the Cayman trough; 2) Late Cretaceous GAC and CLIP of oceanic arc and plateau origin, whose northern, deformed edge corresponds to the mapped Siuna belt of northern Nicaragua. This crustal province has a ~15-20-km-thick crust and is largely undeformed and extends across the Lower Nicaraguan Rise, Hess fault, to the southern limit of the Colombian basin where about 300 km of this province has been subducted beneath the accretionary wedge of the South Caribbean deformed belt of northwestern South America; and 3) Eocene to recent accretionary prism and intramontane basins on continental crust of northern South America, where Miocene accelerated exhumation and erosion of Paleogene and Cretaceous rocks reflect either shallow subduction of the CLIP or the Panama collisional event to the southwest.

  15. Genetics

    Christensen, Kaare; McGue, Matt

    2016-01-01

    The sequenced genomes of individuals aged ≥80 years, who were highly educated, self-referred volunteers and with no self-reported chronic diseases were compared to young controls. In these data, healthy ageing is a distinct phenotype from exceptional longevity and genetic factors that protect...

  16. The Paleo-Indian Entry into South America According to Mitogenomes.

    Brandini, Stefania; Bergamaschi, Paola; Cerna, Marco Fernando; Gandini, Francesca; Bastaroli, Francesca; Bertolini, Emilie; Cereda, Cristina; Ferretti, Luca; Gómez-Carballa, Alberto; Battaglia, Vincenza; Salas, Antonio; Semino, Ornella; Achilli, Alessandro; Olivieri, Anna; Torroni, Antonio

    2018-02-01

    Recent and compelling archaeological evidence attests to human presence ∼14.5 ka at multiple sites in South America and a very early exploitation of extreme high-altitude Andean environments. Considering that, according to genetic evidence, human entry into North America from Beringia most likely occurred ∼16 ka, these archeological findings would imply an extremely rapid spread along the double continent. To shed light on this issue from a genetic perspective, we first completely sequenced 217 novel modern mitogenomes of Native American ancestry from the northwestern area of South America (Ecuador and Peru); we then evaluated them phylogenetically together with other available mitogenomes (430 samples, both modern and ancient) from the same geographic area and, finally, with all closely related mitogenomes from the entire double continent. We detected a large number (N = 48) of novel subhaplogroups, often branching into further subclades, belonging to two classes: those that arose in South America early after its peopling and those that instead originated in North or Central America and reached South America with the first settlers. Coalescence age estimates for these subhaplogroups provide time boundaries indicating that early Paleo-Indians probably moved from North America to the area corresponding to modern Ecuador and Peru over the short time frame of ∼1.5 ka comprised between 16.0 and 14.6 ka. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  17. Holocene re-colonisation, central-marginal distribution and habitat specialisation shape population genetic patterns within an Atlantic European grass species.

    Harter, D E V; Jentsch, A; Durka, W

    2015-05-01

    Corynephorus canescens (L.) P.Beauv. is an outbreeding, short-lived and wind-dispersed grass species, highly specialised on scattered and disturbance-dependent habitats of open sandy sites. Its distribution ranges from the Iberian Peninsula over Atlantic regions of Western and Central Europe, but excludes the two other classical European glacial refuge regions on the Apennine and Balkan Peninsulas. To investigate genetic patterns of this uncommon combination of ecological and biogeographic species characteristics, we analysed AFLP variation among 49 populations throughout the European distribution range, expecting (i) patterns of SW European glacial refugia and post-glacial expansion to the NE; (ii) decreasing genetic diversity from central to marginal populations; and (iii) interacting effects of high gene flow and disturbance-driven genetic drift. Decreasing genetic diversity from SW to NE and distinct gene pool clustering imply refugia on the Iberian Peninsula and in western France, from where range expansion originated towards the NE. High genetic diversity within and moderate genetic differentiation among populations, and a significant pattern of isolation-by-distance indicate a gene flow drift equilibrium within C. canescens, probably due to its restriction to scattered and dynamic habitats and limited dispersal distances. These features, as well as the re-colonisation history, were found to affect genetic diversity gradients from central to marginal populations. Our study emphasises the need for including the specific ecology into analyses of species (re-)colonisation histories and range centre-margin analyses. To account for discontinuous distributions, new indices of marginality were tested for their suitability in studies of centre-periphery gradients. © 2014 German Botanical Society and The Royal Botanical Society of the Netherlands.

  18. Implications of the Central America-Dominican Republic-Free Trade Agreement for the nutrition transition in Central America Implicaciones del Tratado de Libre Comercio entre Centroamérica y República Dominicana sobre la transición alimentaria en Centroamérica

    Corinna Hawkes

    2008-11-01

    Full Text Available OBJECTIVES: To identify potential impacts of the Central America-Dominican Republic-Free Trade Agreement (CAFTA-DR on food consumption patterns associated with the nutrition transition, obesity, and diet-related chronic diseases. METHODS: Examination of CAFTA-DR agreement to identify measures that have the potential to affect food availability and retail prices. RESULTS: CAFTA-DR includes agreements on tariffs, tariff-rate quotas (TRQs, and sanitary and phytosanitary regulations with direct implications for the availability and prices of various foods. Agreements on investment, services, and intellectual property rights (IPR are also relevant because they create a business climate more conducive to long-term investment by the transnational food industry. Trade liberalization under CAFTA-DR is likely to increase availability and lower relative prices of two food groups associated with the nutrition transition: meat and processed foods. These outcomes are expected to occur as the direct result of increased imports from the United States and increased production by U.S. companies based in Central America, and the indirect result of increased domestic meat production (due to increased availability of cheaper animal feed and increased production of processed foods by domestic companies (due to a more competitive market environment. CONCLUSIONS: CAFTA-DR is likely to further the nutrition transition in Central America by increasing the consumption of meat; highly processed foods; and new, non-traditional foods. The public health community should be more aware of the implications of trade agreements for dietary health. Governments and related stakeholders should assess the coherence between changes fostered by specific trade agreements with national policies on diet and nutrition.OBJETIVOS: Identificar el posible impacto del Tratado de Libre Comercio entre Centroamérica y República Dominicana (TLCCA-RD sobre el patrón de consumo de alimentos

  19. The Genetic Contribution of West-African Ancestry to Protection against Central Obesity in African-American Men but Not Women: Results from the ARIC and MESA Studies.

    Klimentidis, Yann C; Arora, Amit; Zhou, Jin; Kittles, Rick; Allison, David B

    2016-01-01

    Over 80% of African-American (AA) women are overweight or obese. A large racial disparity between AA and European-Americans (EA) in obesity rates exists among women, but curiously not among men. Although socio-economic and/or cultural factors may partly account for this race-by-sex interaction, the potential involvement of genetic factors has not yet been investigated. Among 2814 self-identified AA in the Atherosclerosis Risk in Communities study, we estimated each individual's degree of West-African genetic ancestry using 3437 ancestry informative markers. We then tested whether sex modifies the association between West-African genetic ancestry and body mass index (BMI), waist-circumference (WC), and waist-to-hip ratio (WHR), adjusting for income and education levels, and examined associations of ancestry with the phenotypes separately in males and females. We replicated our findings in the Multi-Ethnic Study of Atherosclerosis (n = 1611 AA). In both studies, we find that West-African ancestry is negatively associated with obesity, especially central obesity, among AA men, but not among AA women (pinteraction = 4.14 × 10(-5) in pooled analysis of WHR). In conclusion, our results suggest that the combination of male gender and West-African genetic ancestry is associated with protection against central adiposity, and suggest that the large racial disparity that exists among women, but not men, may be at least partly attributed to genetic factors.

  20. Outline of tectonic geology of the cenozoic Pacific volcanic zone concerned with geothermal areas in the central America; Chubei ni okeru chinetsutai wo tomonau shinseidai Taiheiyo kazantai no chishitsu gaisetsu

    Yamasaki, T [Kyushu University, Fukuoka (Japan); Matsumoto, Y [Yamaguchi University, Yamaguchi (Japan)

    1994-09-16

    For the purpose of technological cooperation on geothermal development, investigations and discussions have been given on the geological background in the geothermal areas in Central America where the Pacific volcanic zone stretches. The geology in Central America is divided largely into three geological structures distributed in a band form in the east-west direction. Among these structure, the Pacific Volcanic Province is a Caenozoic volcanic area ranging along the Pacific Ocean coast in the south-east direction, where young and active Quarternary volcanoes are lined straight over a distance of 1,400 km. The geological structure is such that continuously traceable rift valley or pit structure agrees with the array of volcanoes. The long and wide rift valley that governs this volcanic activity forms the base of the geothermal areas dotted in the above structure. Guatemala had been proceeding with a 24-MW power plant plan in Zunil, the most important point, but the construction has been delayed because of a landslide that caused impediment to the productive wells. The plant completion is now scheduled for 1995. El Salvador is the most advanced country in geothermal power generation, which operates three plants in the Ahuachapa geothermal area, with the output reaching 95 MW. The geothermal condition per production well is 110 tons per hour at 250{degree}C. Nicaragua had been successful in generating power of 70 KW with two plants in Momtombo by 1989. 22 refs., 8 figs., 4 tabs.

  1. Assessment of clinical efficacy and safety in a randomized double-blind study of etanercept and sulfasalazine in patients with ankylosing spondylitis from Eastern/Central Europe, Latin America, and Asia.

    Damjanov, Nemanja; Shehhi, Waleed Al; Huang, Feng; Kotak, Sameer; Burgos-Vargas, Ruben; Shirazy, Khalid; Bananis, Eustratios; Szumski, Annette; Llamado, Lyndon J Q; Mahgoub, Ehab

    2016-05-01

    Despite the demonstrated efficacy of etanercept for the treatment of ankylosing spondylitis (AS), sulfasalazine is often prescribed, especially in countries with limited access to biologic agents. The objective of this subset analysis of the ASCEND trial was to compare the efficacy of etanercept and sulfasalazine in treating patients with AS from Asia, Eastern/Central Europe, and Latin America. A total of 287 patients, 190 receiving etanercept 50 mg once weekly and 97 receiving sulfasalazine 3 g daily, from eight countries were included in this subset analysis. Differences in disease activity and patient-reported outcomes assessing health-related quality-of-life (HRQoL) parameters in response to treatment were analyzed using the Cochran-Mantel-Haenszel test for categorical efficacy endpoints and analysis of covariance model for continuous variables. At week 16, a significantly greater proportion of patients receiving etanercept achieved ASAS20 (79.0 %) compared with patients receiving sulfasalazine (61.9 %; p = 0.002). At week 16, treatment with etanercept also resulted in significantly better responses than sulfasalazine for ASAS40 (64.7 vs. 35.1 %; p Disease Activity Index (65.8 vs. 42.3 %; p Asia, Central/Eastern Europe, and Latin America.

  2. Use of nuclear and related techniques in studies of agroecological effects resulting from the use of persistent pesticides in Central America. Report of a final research co-ordination meeting

    1999-09-01

    The use of pesticides for the control of pests of agriculture and vectors of human and animal diseases in the countries of Central America is the highest per capita and one of the most intense in the world. There are reports of acute toxicity and chronic effects among farm workers. There are also reports that pesticide residues in food frequently exceed the Codex Alimentarius Commission's maximum residue levels (MRLs) and shipments of foodstuffs have been rejected by importing countries due to the presence of excessive residues of pesticides. Pesticides are also implicated in the contamination of continental and coastal waters. The indiscriminate use of pesticides would be expected to also aggravate pest problems by adversely affecting populations of beneficial arthropods and causing the development of resistance in pest populations. The Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture initiated a co-ordinated research project in 1992 to generate information on residues of pesticides in the environment, their persistence under local conditions and effect on local species of beneficial arthropods in agricultural and adjacent areas in the countries of Central America. Such information could be used in the implementation of legislation to control the distribution and use of pesticides and the development and application of integrated pest management programmes. Scientists from Costa Rica, Guatemala, Honduras, Nicaragua, Panama and the United States of America participated in this project. This TECDOC reports on the accomplishments of the project and includes the papers presented at the final Research Co-ordination Meeting held in Panama City, Panama, 20-24 April 1998

  3. You Can't Unscramble an Egg: Population Genetic Structure of Oncorhynchus mykiss in the California Central Valley Inferred from Combined Microsatellite and Single Nucleotide Polymorphism Data

    Devon E. Pearse

    2015-12-01

    Full Text Available doi: http://dx.doi.org/10.15447/sfews.2015v13iss4art3Steelhead/rainbow trout (Oncorhynchus mykiss are found in all of the major tributaries of the Sacramento and San Joaquin rivers, which flow through California’s Central Valley and enter the ocean through San Francisco Bay and the Golden Gate. This river system is heavily affected by water development, agriculture, and invasive species, and salmon and trout hatchery propagation has been occurring for over 100 years. We collected genotype data for 18 highly variable microsatellite loci and 95 single nucleotide polymorphisms (SNPs from more than 1,900 fish from Central Valley drainages to analyze genetic diversity, population structure, differentiation between populations above and below dams, and the relationship of Central Valley O. mykiss populations to coastal California steelhead. In addition, we evaluate introgression by both hatchery rainbow trout strains, which have primarily native Central Valley ancestry, and imported coastal steelhead stocks. In contrast to patterns typical of coastal steelhead, Central Valley O. mykiss above and below dams within the same tributary were not found to be each others’ closest relatives, and we found no relationship between genetic and geographic distance among below-barrier populations. While introgression by hatchery rainbow trout strains does not appear to be widespread among above-barrier populations, steelhead in the American River and some neighboring tributaries have been introgressed by coastal steelhead. Together, these results demonstrate that the ancestral population genetic structure that existed among Central Valley tributaries has been significantly altered in contemporary populations. Future conservation, restoration, and mitigation efforts should take this into account when working to meet recovery planning goals.

  4. Prevalence and genetic characterization of Cryptosporidium species and Giardia duodenalis in lambs in Oromia Special Zone, Central Ethiopia.

    Wegayehu, Teklu; Karim, Md Robiul; Li, Junqiang; Adamu, Haileeyesus; Erko, Berhanu; Zhang, Longxian; Tilahun, Getachew

    2017-01-17

    Cryptosporidium and Giardia duodenalis are gastro-intestinal parasites that infect human and animals worldwide. Both parasites share a broad host range and are believed to be zoonosis. The aim of this study was to identify the species of Cryptosporidium and assemblages of G. duodenalis in lambs and to elucidate their role in zoonotic transmission. A total of 389 fecal samples were collected from lambs and screened by microscopy and nested PCR targeting the small-subunit ribosomal RNA for Cryptosporidium; and the small-subunit ribosomal RNA, triose phosphate isomerase, β-giardin, and glutamate dehydrogenase genes for G. duodenalis. The prevalence of Cryptosporidium and G. duodenalis was 2.1% (8/389) and 2.6% (10/389), respectively. The infection rate at the three study sites ranged from 1.3 to 3.1% for Cryptosporidium and 1.6 to 3.9% for G. duodenalis; but variation was not statistically significant (p > 0.05). The finding also showed that there is no sex and age group associated difference in the occurrence of Cryptosporidium and G. duodenalis infections in lambs. Sequence analysis revealed that lambs were mono-infection with C. ubiquitum and G. duodenalis assemblage E. The analysis also indicated the presence of genetic variation within isolates of assemblage E; with 4 of them are novel genotypes at the small-subunit ribosomal RNA, β-giardin, and glutamate dehydrogenase genes. The findings of the current study showed that lambs are capable of harboring C. ubiquitum and G. duodenalis assemblage E. This finding suggests that lambs might be sources for potentially zoonotic Cryptosporidium species. This was first molecular study in lambs and contributes to a better understanding of the epidemiology of Cryptosporidium and G. duodenalis in central Ethiopia.

  5. Population Genetics of Overwintering Monarch Butterflies, Danaus plexippus (Linnaeus), from Central Mexico Inferred from Mitochondrial DNA and Microsatellite Markers

    Pfeiler, Edward; Nazario-Yepiz, Nestor O.; Pérez-Gálvez, Fernan; Chávez-Mora, Cristina Alejandra; Laclette, Mariana Ramírez Loustalot; Rendón-Salinas, Eduardo

    2017-01-01

    Abstract Population genetic variation and demographic history in Danaus plexippus (L.), from Mexico were assessed based on analyses of mitochondrial cytochrome c oxidase subunit I (COI; 658 bp) and subunit II (COII; 503 bp) gene segments and 7 microsatellite loci. The sample of 133 individuals included both migratory monarchs, mainly from 4 overwintering sites within the Monarch Butterfly Biosphere Reserve (MBBR) in central Mexico (states of Michoacán and México), and a nonmigratory population from Irapuato, Guanajuato. Haplotype (h) and nucleotide (π) diversities were relatively low, averaging 0.466 and 0.00073, respectively, for COI, and 0.629 and 0.00245 for COII. Analysis of molecular variance of the COI data set, which included additional GenBank sequences from a nonmigratory Costa Rican population, showed significant population structure between Mexican migratory monarchs and nonmigratory monarchs from both Mexico and Costa Rica, suggesting limited gene flow between the 2 behaviorally distinct groups. Interestingly, while the COI haplotype frequencies of the nonmigratory populations differed from the migratory, they were similar to each other, despite the great physical distance between them. Microsatellite analyses, however, suggested a lack of structure between the 2 groups, possibly owing to the number of significant deviations from Hardy–Weinberg equilibrium resulting from heterzoygote deficiencies found for most of the loci. Estimates of demographic history of the combined migratory MBBR monarch population, based on the mismatch distribution and Bayesian skyline analyses of the concatenated COI and COII data set (n = 89) suggested a population expansion dating to the late Pleistocene (~35000–40000 years before present) followed by a stable effective female population size (Nef) of about 6 million over the last 10000 years. PMID:28003372

  6. Building America

    Brad Oberg

    2010-12-31

    IBACOS researched the constructability and viability issues of using high performance windows as one component of a larger approach to building houses that achieve the Building America 70% energy savings target.

  7. The Latin-American region and the challenges to develop one homogeneous and harmonized hazard model: preliminary results for the Caribbean and Central America regions in the GEM context

    Garcia, J.; Arcila, M.; Benito, B.; Eraso, J.; García, R.; Gomez Capera, A.; Pagani, M.; Pinho, R.; Rendon, H.; Torres, Y.

    2013-05-01

    Latin America is a seismically active region with complex tectonic settings that make the creation of hazard models challenging. Over the past two decades PSHA studies have been completed for this region in the context of global (Shedlock, 1999), regional (Dimaté et al., 1999) and national initiatives. Currently different research groups are developing new models for various nations. The Global Earthquake Model (GEM), an initiative aiming at the creation of a large global community working collaboratively on building hazard and risk models using open standards and tools, is promoting the collaboration between different national projects and groups so as to facilitate the creation of harmonized regional models. The creation of a harmonized hazard model can follow different approaches, varying from a simple patching of available models to a complete homogenisation of basic information and the subsequent creation of a completely new PSHA model. In this contribution we describe the process and results of a first attempt aiming at the creation of a community based model covering the Caribbean and Central America regions. It consists of five main steps: 1- Identification and collection of available PSHA input models; 2- Analysis of the consistency, transparency and reproducibility of each model; 3- Selection (if more then a model exists for the same region); 4- Representation of the models in a standardized format and incorporation of new knowledge from recent studies; 5- Proposal(s) of harmonization We consider some PHSA studies completed over the latest twenty years in the region comprising the Caribbean (CAR), Central America (CAM) and northern South America (SA), we illustrate a tentative harmonization of the seismic source geometries models and we discuss the steps needed toward a complete harmonisation of the models. Our will is to have a model based on best practices and high standards created though a combination of knowledge and competences coming from the

  8. Development of food crops by modern biotechnology techniques in Central America Desarrollo de cultivos y alimentos por técnicas de biotecnología moderna en Centroamérica

    Giovanni Garro Monge

    2012-12-01

    Full Text Available In the last decade, the adoption of Genetically Modified Crops (GMC has increased in stages worldwide. The worldwide total area planted with biotech crops reached 148 million hectares by 2010, also increasing the number of farmers around the world who decided to produce crops with this technology. At the regional level there are different responses of government agencies by generating rules and regu- lations according to the reality of these countries. In Central America, countries with greater partici- pation in the development and cultivation of food biotechnology techniques are Guatemala (papa- ya, Honduras (beans and maize and Costa Rica (cotton, soybean and pineapple, placing the latter two in the 29 countries with more GMO planting crops worldwide in 2010. Some of the countries of the region have implemented governance structures for the regulation through technical committees on Biosafety. The most important characteristics in terms of trade continue to be those that confer herbicide tolerance or pest resistance. But notice the incur- sion of new products that contain changes in their content, which are emerging as an alternative with great perspectives in the region. These experiences of culture and Biosafety regula- tion at the regional level could be a successful and progressive development of agricultural and food biotechnology in the near future.En la última década, la adopción de Cultivos Genéticamente Modificados (CGM se ha incre- mentado de forma escalonada a nivel mundial. El área sembrada con cultivos biotecnológicos llegó a un total de 148 millones de hectáreas en 2010, aumentando también el número de agricultores que decidieron producir este tipo de cultivos. A nivel regional, se producen respuestas diversas de los órganos gubernamentales mediante reglamen- tos y normativas acordes con la realidad local. En Centroamérica, los países con mayor participación en el desarrollo y cultivo de alimentos utilizando t

  9. Latin America Report.

    1986-11-17

    yesterday, the reserved market throughout the country for in- formatics has also been extended to computer software programs. The DIARIO OFICIAL ...Pemex Northern States Price Cuts 97 PARAGUAY Journalists Union Denounces Arrest of Members (EL DIARIO , 25 Oct 86) .....; .. 98 Police...topple the elected government in Man- • agua — including US$200 000 to the anti-San- dinista "Friends of the Democratic Centre in Central America". I

  10. Genetic characterization of Kenai brown bears (Ursus arctos): Microsatellite and mitochondrial DNA control region variation in brown bears of the Kenai Peninsula, south central Alaska

    Jackson, J.V.; Talbot, S.L.; Farley, S.

    2008-01-01

    We collected data from 20 biparentally inherited microsatellite loci, and nucleotide sequence from the maternally inherited mitochondrial DNA (mtDNA) control region, to determine levels of genetic variation of the brown bears (Ursus arctos L., 1758) of the Kenai Peninsula, south central Alaska. Nuclear genetic variation was similar to that observed in other Alaskan peninsular populations. We detected no significant inbreeding and found no evidence of population substructuring on the Kenai Peninsula. We observed a genetic signature of a bottleneck under the infinite alleles model (IAM), but not under the stepwise mutation model (SMM) or the two-phase model (TPM) of microsatellite mutation. Kenai brown bears have lower levels of mtDNA haplotypic diversity relative to most other brown bear populations in Alaska. ?? 2008 NRC.

  11. WITHIN-POPULATION GENETIC DIVERSITY OF CLIMBING PLANTS AND TREES IN A TEMPERATE FOREST IN CENTRAL CHILE

    Torres-Díaz, Cristian; Ruiz, Eduardo; Salgado-Luarte, Cristian; Molina-Montenegro, Marco A; Gianoli, Ernesto

    2013-01-01

    The climbing habit is a key innovation in angiosperm evolution: climbing plant taxa have greater species richness than their non-climbing sister groups. It is considered that highly diversified clades should show increased among-population genetic differentiation. Less clear is the expected pattern regarding within-population genetic diversity in speciose lineages. We tested the hypothesis of greater within-population genetic diversity in climbing plants compared to trees in a temperate fores...

  12. Psychological impact of von Hippel-Lindau genetic screening in patients with a previous history of hemangioblastoma of the central nervous system.

    Rochette, Claire; Baumstarck, Karine; Canoni-Zattara, Hélène; Abdullah, Ahmad Esmaeel; Figarella-Branger, Dominique; Pertuit, Morgane; Barlier, Anne; Castinetti, Frédéric; Pacak, Karel; Metellus, Philippe; Taïeb, David

    2018-05-15

    Von Hippel-Lindau (VHL) syndrome is a hereditary cancer syndrome characterized by a high risk of developing benign and malignant tumors, including central nervous system hemangioblastomas (CNS HBs). For an early diagnosis of VHL, before the occurrence of cancers (especially renal cell carcinoma), it is of huge importance to initiate VHL genetic testing in at-risk patients. The aim of the study was to assess the psychological impact of VHL genetic testing in patients previously diagnosed with a CNS HB. From 1999 until 2015, 55 patients underwent surgery for CNS HBs. Eleven patients were already screened for VHL mutations and 3 patients deceased before the start of the study. From the remaining 42 patients, 24 were accepted to be enrolled in the study. Assessment of psychological impact of VHL genetic testing was performed by measuring anxiety levels, mood disorders, quality of life, and psychological consequences of genetic screening. Twenty-one of the enrolled 24 patients underwent VHL genetic testing and 12 patients came back for the communication of positive genetic results. The baseline psychological status did not differ between these 2 groups. Patients who attended the visit of communication of genetic results had similar anxiety levels compared to those who had not. Furthermore, they also experienced an improvement in the level of anxiety and two QoL dimension scores compared to their baseline status. In summary, there is no evidence of a negative psychosocial impact of VHL genetic testing in patients with a previous history of CNS HB. We, therefore, recommend the recall of patients who have not been previously screened.

  13. Genetic conservation planning for forest tree species in Western North America under future climate change: Employing a novel approach to identify conservation gaps

    L.K. Gray; E.J. Russell; Q.E. Barber; A. Hamann

    2017-01-01

    Among the 17 provinces, territories, and states that comprise western North America, approximately 18 percent of the 8.4 million km2 of forested land base is designated as protected areas to ensure the in situ conservation of forest biodiversity. Jurisdictions vary substantially however, in their responsibilities, protected area coverage, and conservation policies....

  14. Genetic diversity and structure of western white pine (Pinus monticola) in North America: A baseline study for conservation, restoration, and addressing impacts of climate change

    Mee-Sook Kim; Bryce A. Richardson; Geral I. McDonald; Ned B. Klopfenstein

    2010-01-01

    Western white pine (Pinus monticola) is an economically and ecologically important species in western North America that has declined in prominence over the past several decades, mainly due to the introduction of Cronartium ribicola (cause of white pine blister rust) and reduced opportunities for regeneration. Amplified fragment length polymorphism (AFLP) markers were...

  15. Genetic diversity in populations of Isatis glauca Aucher ex Boiss. ssp. from Central Anatolia in Turkey, as revealed by AFLP analysis.

    Özbek, Özlem; Görgülü, Elçin; Yıldırımlı, Şinasi

    2013-12-01

    Isatidae L. is a complex and systematically difficult genus in Brassicaceae. The genus displays great morphological polymorphism, which makes the classification of species and subspecies difficult as it is observed in Isatis glauca Aucher ex Boiss. The aim of this study is characterization of the genetic diversity in subspecies of Isatis glauca Aucher ex Boiss. distributed widely in Central Anatolia, in Turkey by using Amplified Fragment Length Polymorphism (AFLP) technique. Eight different Eco RI-Mse I primer combinations produced 805 AFLP loci, 793 (98.5%) of which were polymorphic in 67 accessions representing nine different populations. The data obtained by AFLP was computed with using GDA (Genetic Data Analysis) and STRUCTURE (version 2.3.3) software programs for population genetics. The mean proportion of the polymorphic locus (P), the mean number of alleles (A), the number of unique alleles (U) and the mean value of gene diversity (He) were 0.59, 1.59, 20, and 0.23 respectively. The coancestry coefficient (ϴ) was 0.24. The optimal number of K was identified as seven. The principal component analysis (PCA) explained 85.61% of the total genetic variation. Isatis glauca ssp. populations showed a high level of genetic diversity, and the AFLP analysis revealed that high polymorphism and differentiated subspecies could be used conveniently for population genetic studies. The principal coordinate analysis (PCoA) based on the dissimilarity matrix, the dendrogram drawn with UPGMA method and STRUCTURE cluster analysis distinguished the accessions successfully. The accessions formed distinctive population structures for populations AA, AB, E, K, and S. Populations AG1 and AG2 seemed to have similar genetic content, in addition, in both populations several hybrid individuals were observed. The accessions did not formed distinctive population structures for both populations AI and ANP. Consequently, Ankara province might be the area, where species Isatis glauca Aucher

  16. High-resolution sequence stratigraphy of lower Paleozoic sheet sandstones in central North America: The role of special conditions of cratonic interiors in development of stratal architecture

    Runkel, Anthony C.; Miller, J.F.; McKay, R.M.; Palmer, A.R.; Taylor, John F.

    2007-01-01

    Well-known difficulties in applying sequence stratigraphic concepts to deposits that accumulated across slowly subsiding cratonic interior regions have limited our ability to interpret the history of continental-scale tectonism, oceanographic dynamics of epeiric seas, and eustasy. We used a multi-disciplinary approach to construct a high-resolution stratigraphic framework for lower Paleozoic strata in the cratonic interior of North America. Within this framework, these strata proved readily amenable to modern sequence stratigraphic techniques that were formulated based on successions along passive margins and in foreland basins, settings markedly different from the cratonic interior. Parasequences, parasequence stacking patterns, systems tracts, maximum flooding intervals, and sequence-bounding unconformities can be confidently recognized in the cratonic interior using mostly standard criteria for identification. The similarity of cratonic interior and foreland basin successions in size, geometry, constituent facies, and local stacking patterns of nearshore parasequences is especially striking. This similarity indicates that the fundamental processes that establish shoreface morphology and determine the stratal expression of retreat and progradation were likewise generally the same, despite marked differences in tectonism, physiography, and bathymetry between the two settings. Our results do not support the widespread perception that Paleozoic cratonic interior successions are so anomalous in stratal geometries, and constitute such a poor record of time, that they are poorly suited for modern sequence stratigraphic analyses. The particular arrangement of stratal elements in the cratonic interior succession we studied is no more anomalous or enigmatic than the variability in architecture that sets all sedimentary successions apart from one another. Thus, Paleozoic strata of the cratonic interior are most appropriately considered as a package that belongs in a

  17. Reproductive performance of dairy cattle in Latin America

    Taylor, R.T.; Barnabe, R.C.; Morales, J.R.

    1990-01-01

    The review describes the commonly practised systems of milk production in sample countries within the five major topographical/climatological subregions of Latin America, viz. Central America, the Caribbean, the South American subtropics, the Andes and the Temperate Zone. The state of development and importance of the dairy industry to the economy of each country are discussed. Production and reproduction indices are quoted, as are the genetic make-up of the dairy herds, husbandry practices and the quality of livestock management. It is clear that there is an enormous capacity for improvement in the efficiency of milk production systems in the Latin American region as a whole; to achieve this improvement, there is an urgent need to pursue on-farm based research aimed at identifying constraints to the performance of dairy cattle and the implementation of low cost management/nutritional/health control measures. (author)

  18. Textbook America.

    Karp, Walter

    1980-01-01

    Focuses on how political attitudes have been influenced by American history textbooks at various times throughout history. Excerpts from traditional and revisionist textbooks are presented, with emphasis on "America Revised" by Frances FitzGerald. Journal available from Harper's Magazine Co., 2 Park Ave., New York, NY 10016. (DB)

  19. Global Dispersal Pattern of HIV Type 1 Subtype CRF01_AE: A Genetic Trace of Human Mobility Related to Heterosexual Sexual Activities Centralized in Southeast Asia.

    Angelis, Konstantinos; Albert, Jan; Mamais, Ioannis; Magiorkinis, Gkikas; Hatzakis, Angelos; Hamouda, Osamah; Struck, Daniel; Vercauteren, Jurgen; Wensing, Annemarie M J; Alexiev, Ivailo; Åsjö, Birgitta; Balotta, Claudia; Camacho, Ricardo J; Coughlan, Suzie; Griskevicius, Algirdas; Grossman, Zehava; Horban, Andrzej; Kostrikis, Leondios G; Lepej, Snjezana; Liitsola, Kirsi; Linka, Marek; Nielsen, Claus; Otelea, Dan; Paredes, Roger; Poljak, Mario; Puchhammer-Stöckl, Elisabeth; Schmit, Jean-Claude; Sönnerborg, Anders; Staneková, Danica; Stanojevic, Maja; Boucher, Charles A B; Kaplan, Lauren; Vandamme, Anne-Mieke; Paraskevis, Dimitrios

    2015-06-01

    Human immunodeficiency virus type 1 (HIV-1) subtype CRF01_AE originated in Africa and then passed to Thailand, where it established a major epidemic. Despite the global presence of CRF01_AE, little is known about its subsequent dispersal pattern. We assembled a global data set of 2736 CRF01_AE sequences by pooling sequences from public databases and patient-cohort studies. We estimated viral dispersal patterns, using statistical phylogeographic analysis run over bootstrap trees estimated by the maximum likelihood method. We show that Thailand has been the source of viral dispersal to most areas worldwide, including 17 of 20 sampled countries in Europe. Japan, Singapore, Vietnam, and other Asian countries have played a secondary role in the viral dissemination. In contrast, China and Taiwan have mainly imported strains from neighboring Asian countries, North America, and Africa without any significant viral exportation. The central role of Thailand in the global spread of CRF01_AE can be probably explained by the popularity of Thailand as a vacation destination characterized by sex tourism and by Thai emigration to the Western world. Our study highlights the unique case of CRF01_AE, the only globally distributed non-B clade whose global dispersal did not originate in Africa. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  20. Genetic diversity of Plasmodium falciparum isolates from naturally infected children in north-central Nigeria using the merozoite surface protein-2 as molecular marker.

    Oyedeji, Segun Isaac; Awobode, Henrietta Oluwatoyin; Anumudu, Chiaka; Kun, Jürgen

    2013-08-01

    To characterize the genetic diversity of Plasmodium falciparum (P. falciparum) field isolates in children from Lafia, North-central Nigeria, using the highly polymorphic P. falciparum merozoite surface protein 2 (MSP-2) gene as molecular marker. Three hundred and twenty children were enrolled into the study between 2005 and 2006. These included 140 children who presented with uncomplicated malaria at the Dalhatu Araf Specialist Hospital, Lafia and another 180 children from the study area with asymptomatic infection. DNA was extracted from blood spot on filter paper and MSP-2 genes were genotyped using allele-specific nested PCR in order to analyze the genetic diversity of parasite isolates. A total of 31 and 34 distinct MSP-2 alleles were identified in the asymptomatic and uncomplicated malaria groups respectively. No difference was found between the multiplicity of infection in the asymptomatic group and that of the uncomplicated malaria group (P>0.05). However, isolates of the FC27 allele type were dominant in the asymptomatic group whereas isolates of the 3D7 allele type were dominant in the uncomplicated malaria group. This study showed a high genetic diversity of P. falciparum isolates in North-central Nigeria and is comparable to reports from similar areas with high malaria transmission intensity. Copyright © 2013 Hainan Medical College. Published by Elsevier B.V. All rights reserved.

  1. A psychology of liberation for Central America: the unfinished work of Ignacio Martín-Baró (1942-1989).

    Gondra, José María

    2013-01-01

    On November 16, 1989 the world was shocked by the news of the assassination of six Jesuits at the campus of the Universidad Centro Americana José Simeón Cañas (UCA) in San Salvador, El Salvador. Among those murdered by government soldiers was Ignacio Martín-Baró, a PhD in social psychology from the University of Chicago who at that time was the Vice-Rector for Academic Affairs and Vice-President of the Interamerican Society of Psychology (SIP). Drawing on Martín-Baró's published writings and non-published academic papers and correspondence, this article traces the evolution of the Spanish-born Jesuit who became a leading authority among Latin American social psychologists. In particular, it analyzes his project of becoming a clinical psychologist under the influence of psychoanalysis, his critical social psychology aimed to "de-ideologize" the oppressed social classes of El Salvador, and his ultimate project of a psychology of liberation for Latin America. Martín-Baró's work came to a tragic end just when it began to bear fruit, but it stands as a testimony to a lifetime committed to the human values of democracy, social justice and service to society's poorest and most neglected.

  2. Mitochondrial DNA confirms low genetic variation of the greater mouse-eared bats, Myotis myotis, in Central Europe

    Bryja, Josef; Uhrin, M.; Kaňuch, P.; Bémová, P.; Martínková, Natália; Zukal, Jan

    2010-01-01

    Roč. 12, č. 1 (2010), s. 73-81 ISSN 1508-1109 R&D Projects: GA ČR GA206/01/1555; GA MŠk LC06073 Grant - others:VEGA(SK) 2/0130/08 Institutional research plan: CEZ:AV0Z60930519 Keywords : genetic structure * mtDNA * control region * phylogeography * Myotis myotis Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 1.012, year: 2010

  3. PhenomeCentral: An Integrated Portal for Sharing and Searching Patient Phenotype Data for Rare Genetic Disorders.

    Brudno, Michael; Girdea, Marta; Dumitriu, Sergiu; Buske, Orion; Köhler, Sebastian; Robinson, Peter N.; Brookes, Andrew J.; Boycott, Kym; Boerkoel, Cornelius F.; Gahl, William A.; CARE RARE, Canadian for Consortium; NIH, Undiagnosed Diseases Program

    2014-01-01

    The availability of low-cost genome sequencing has allowed for the identification of the molecular cause of hundreds of rare genetic disorders. Solved disorders, however, only represent the “tip of the iceberg”. Because the discovery of disease-causing variants typically requires confirmation of the mutation or gene in multiple unrelated individuals, an even larger number of genetic disorders remain unsolved due to difficulty identifying second families. With many groups now tackling these re...

  4. The NIH genetic testing registry: a new, centralized database of genetic tests to enable access to comprehensive information and improve transparency.

    Rubinstein, Wendy S; Maglott, Donna R; Lee, Jennifer M; Kattman, Brandi L; Malheiro, Adriana J; Ovetsky, Michael; Hem, Vichet; Gorelenkov, Viatcheslav; Song, Guangfeng; Wallin, Craig; Husain, Nora; Chitipiralla, Shanmuga; Katz, Kenneth S; Hoffman, Douglas; Jang, Wonhee; Johnson, Mark; Karmanov, Fedor; Ukrainchik, Alexander; Denisenko, Mikhail; Fomous, Cathy; Hudson, Kathy; Ostell, James M

    2013-01-01

    The National Institutes of Health Genetic Testing Registry (GTR; available online at http://www.ncbi.nlm.nih.gov/gtr/) maintains comprehensive information about testing offered worldwide for disorders with a genetic basis. Information is voluntarily submitted by test providers. The database provides details of each test (e.g. its purpose, target populations, methods, what it measures, analytical validity, clinical validity, clinical utility, ordering information) and laboratory (e.g. location, contact information, certifications and licenses). Each test is assigned a stable identifier of the format GTR000000000, which is versioned when the submitter updates information. Data submitted by test providers are integrated with basic information maintained in National Center for Biotechnology Information's databases and presented on the web and through FTP (ftp.ncbi.nih.gov/pub/GTR/_README.html).

  5. Genome-wide association study and genetic diversity analysis on nitrogen use efficiency in a Central European winter wheat (Triticum aestivum L. collection.

    István Monostori

    Full Text Available To satisfy future demands, the increase of wheat (Triticum aestivum L. yield is inevitable. Simultaneously, maintaining high crop productivity and efficient use of nutrients, especially nitrogen use efficiency (NUE, are essential for sustainable agriculture. NUE and its components are inherently complex and highly influenced by environmental factors, nitrogen management practices and genotypic variation. Therefore, a better understanding of their genetic basis and regulation is fundamental. To investigate NUE-related traits and their genetic and environmental regulation, field trials were evaluated in a Central European wheat collection of 93 cultivars at two nitrogen input levels across three seasons. This elite germplasm collection was genotyped on DArTseq® genotypic platform to identify loci affecting N-related complex agronomic traits. To conduct robust genome-wide association mapping, the genetic diversity, population structure and linkage disequilibrium were examined. Population structure was investigated by various methods and two subpopulations were identified. Their separation is based on the breeding history of the cultivars, while analysis of linkage disequilibrium suggested that selective pressures had acted on genomic regions bearing loci with remarkable agronomic importance. Besides NUE, genetic basis for variation in agronomic traits indirectly affecting NUE and its components, moreover genetic loci underlying response to nitrogen fertilisation were also determined. Altogether, 183 marker-trait associations (MTA were identified spreading over almost the entire genome. We found that most of the MTAs were environmental-dependent. The present study identified several associated markers in those genomic regions where previous reports had found genes or quantitative trait loci influencing the same traits, while most of the MTAs revealed new genomic regions. Our data provides an overview of the allele composition of bread wheat

  6. Prevalence and Social Determinants of Smoking in 15 Countries from North Africa, Central and Western Asia, Latin America and Caribbean: Secondary Data Analyses of Demographic and Health Surveys.

    Sreeramareddy, Chandrashekhar T; Pradhan, Pranil Man Singh

    2015-01-01

    Article 20 of the World Health Organisation Framework Convention on Tobacco Control calls for a cross-country surveillance of tobacco use through population-based surveys. We aimed to provide country-level prevalence estimates for current smoking and current smokeless tobacco use and to assess social determinants of smoking. Data from Demographic and Health Surveys done between 2005 and 2012, among men and women from nine North African, Central and West Asian countries and six Latin American and Caribbean countries were analyzed. Weighted country-level prevalence rates were estimated for 'current smoking' and 'current use of smokeless tobacco (SLT) products' among men and women. In each country, social determinants of smoking among men and women were assessed by binary logistic regression analyses by including men's and women's sampling weights to account for the complex survey design. Prevalence of smoking among men was higher than 40% in Armenia (63.1%), Moldova (51.1%), Ukraine (52%), Azerbaijan (49.8 %), Kyrgyz Republic (44.3 %) and Albania (42.52%) but the prevalence of smoking among women was less than 10% in most countries except Ukraine (14.81%) and Jordan (17.96%). The prevalence of smokeless tobacco use among men and women was less than 5% in all countries except among men in the Kyrgyz Republic (10.6 %). Smoking was associated with older age, lower education and poverty among men and higher education and higher wealth among women. Smoking among both men and women was associated with unskilled work, living in urban areas and being single. Smoking among men was very high in Central and West Asian countries. Social pattern of smoking among women that was different from men in education and wealth should be considered while formulating tobacco control policies in some Central and West Asian countries.

  7. Prevalence and Social Determinants of Smoking in 15 Countries from North Africa, Central and Western Asia, Latin America and Caribbean: Secondary Data Analyses of Demographic and Health Surveys.

    Chandrashekhar T Sreeramareddy

    Full Text Available Article 20 of the World Health Organisation Framework Convention on Tobacco Control calls for a cross-country surveillance of tobacco use through population-based surveys. We aimed to provide country-level prevalence estimates for current smoking and current smokeless tobacco use and to assess social determinants of smoking.Data from Demographic and Health Surveys done between 2005 and 2012, among men and women from nine North African, Central and West Asian countries and six Latin American and Caribbean countries were analyzed. Weighted country-level prevalence rates were estimated for 'current smoking' and 'current use of smokeless tobacco (SLT products' among men and women. In each country, social determinants of smoking among men and women were assessed by binary logistic regression analyses by including men's and women's sampling weights to account for the complex survey design.Prevalence of smoking among men was higher than 40% in Armenia (63.1%, Moldova (51.1%, Ukraine (52%, Azerbaijan (49.8 %, Kyrgyz Republic (44.3 % and Albania (42.52% but the prevalence of smoking among women was less than 10% in most countries except Ukraine (14.81% and Jordan (17.96%. The prevalence of smokeless tobacco use among men and women was less than 5% in all countries except among men in the Kyrgyz Republic (10.6 %. Smoking was associated with older age, lower education and poverty among men and higher education and higher wealth among women. Smoking among both men and women was associated with unskilled work, living in urban areas and being single.Smoking among men was very high in Central and West Asian countries. Social pattern of smoking among women that was different from men in education and wealth should be considered while formulating tobacco control policies in some Central and West Asian countries.

  8. Annotated genetic linkage maps of Pinus pinaster Ait. from a Central Spain population using microsatellite and gene based markers.

    de Miguel, Marina; de Maria, Nuria; Guevara, M Angeles; Diaz, Luis; Sáez-Laguna, Enrique; Sánchez-Gómez, David; Chancerel, Emilie; Aranda, Ismael; Collada, Carmen; Plomion, Christophe; Cabezas, José-Antonio; Cervera, María-Teresa

    2012-10-04

    Pinus pinaster Ait. is a major resin producing species in Spain. Genetic linkage mapping can facilitate marker-assisted selection (MAS) through the identification of Quantitative Trait Loci and selection of allelic variants of interest in breeding populations. In this study, we report annotated genetic linkage maps for two individuals (C14 and C15) belonging to a breeding program aiming to increase resin production. We use different types of DNA markers, including last-generation molecular markers. We obtained 13 and 14 linkage groups for C14 and C15 maps, respectively. A total of 211 and 215 markers were positioned on each map and estimated genome length was between 1,870 and 2,166 cM respectively, which represents near 65% of genome coverage. Comparative mapping with previously developed genetic linkage maps for P. pinaster based on about 60 common markers enabled aligning linkage groups to this reference map. The comparison of our annotated linkage maps and linkage maps reporting QTL information revealed 11 annotated SNPs in candidate genes that co-localized with previously reported QTLs for wood properties and water use efficiency. This study provides genetic linkage maps from a Spanish population that shows high levels of genetic divergence with French populations from which segregating progenies have been previously mapped. These genetic maps will be of interest to construct a reliable consensus linkage map for the species. The importance of developing functional genetic linkage maps is highlighted, especially when working with breeding populations for its future application in MAS for traits of interest.

  9. Annotated genetic linkage maps of Pinus pinaster Ait. from a Central Spain population using microsatellite and gene based markers

    de Miguel Marina

    2012-10-01

    Full Text Available Abstract Background Pinus pinaster Ait. is a major resin producing species in Spain. Genetic linkage mapping can facilitate marker-assisted selection (MAS through the identification of Quantitative Trait Loci and selection of allelic variants of interest in breeding populations. In this study, we report annotated genetic linkage maps for two individuals (C14 and C15 belonging to a breeding program aiming to increase resin production. We use different types of DNA markers, including last-generation molecular markers. Results We obtained 13 and 14 linkage groups for C14 and C15 maps, respectively. A total of 211 and 215 markers were positioned on each map and estimated genome length was between 1,870 and 2,166 cM respectively, which represents near 65% of genome coverage. Comparative mapping with previously developed genetic linkage maps for P. pinaster based on about 60 common markers enabled aligning linkage groups to this reference map. The comparison of our annotated linkage maps and linkage maps reporting QTL information revealed 11 annotated SNPs in candidate genes that co-localized with previously reported QTLs for wood properties and water use efficiency. Conclusions This study provides genetic linkage maps from a Spanish population that shows high levels of genetic divergence with French populations from which segregating progenies have been previously mapped. These genetic maps will be of interest to construct a reliable consensus linkage map for the species. The importance of developing functional genetic linkage maps is highlighted, especially when working with breeding populations for its future application in MAS for traits of interest.

  10. Genetic structure of a natural oak community in central Italy: Evidence of gene flow between three sympatric white oak species (Quercus, Fagaceae

    Gaby Antonecchia

    2015-12-01

    Full Text Available Incomplete reproductive barriers between species, especially in sympatric areas where several species coexist, may result in hybridization and an increase in genetic diversity. Here we assessed the amount of genetic diversity in a community of three interfertile and sympatric European oaks (Quercus frainetto Ten., Q. petraea Liebl. Matt. and Q. pubescens Willd. situated in central Italy. We used 11 microsatellite markers derived from Expressed Sequence Tag (EST-SSRs and we implemented a Bayesian clustering analysis to assign individuals to species or hybrids. All genotyped loci were polymorphic for all the species and three genetic clusters corresponding to each species were detected. Significant differences and a higher level of gene flow were observed between the three oak species. Occurrence of hybrids varied markedly within the studied area: hybrids between Q. petraea and Q, pubescens were the most frequent, while hybrids between Q. petraea and Q. frainetto were particularly rare. Q. pubescens and Q. petraea showed the highest number of alleles compared to Q. frainetto,which was characterized by a low number of private, but highly frequent, alleles. However, Q. frainetto showed a lower genetic diversity and a stronger reproductive isolation from the other two oak species.

  11. Whole-exome sequencing reveals genetic variants associated with chronic kidney disease characterized by tubulointerstitial damages in North Central Region, Sri Lanka.

    Nanayakkara, Shanika; Senevirathna, S T M L D; Parahitiyawa, Nipuna B; Abeysekera, Tilak; Chandrajith, Rohana; Ratnatunga, Neelakanthi; Hitomi, Toshiaki; Kobayashi, Hatasu; Harada, Kouji H; Koizumi, Akio

    2015-09-01

    The familial clustering observed in chronic kidney disease of uncertain etiology (CKDu) characterized by tubulointerstitial damages in the North Central Region of Sri Lanka strongly suggests the involvement of genetic factors in its pathogenesis. The objective of the present study is to use whole-exome sequencing to identify the genetic variants associated with CKDu. Whole-exome sequencing of eight CKDu cases and eight controls was performed, followed by direct sequencing of candidate loci in 301 CKDu cases and 276 controls. Association study revealed rs34970857 (c.658G > A/p.V220M) located in the KCNA10 gene encoding a voltage-gated K channel as the most promising SNP with the highest odds ratio of 1.74. Four rare variants were identified in gene encoding Laminin beta2 (LAMB2) which is known to cause congenital nephrotic syndrome. Three out of four variants in LAMB2 were novel variants found exclusively in cases. Genetic investigations provide strong evidence on the presence of genetic susceptibility for CKDu. Possibility of presence of several rare variants associated with CKDu in this population is also suggested.

  12. Prevalence and genetic characterisation of HTLV-1 and 2 dual infections in patients with pulmonary tuberculosis in Central-West Brazil

    Aline Garcia Kozlowski

    2014-02-01

    Full Text Available Human T-cell lymphotropic virus (HTLV may impact the clinical course of tuberculosis (TB. Both infections are highly endemic in Brazil. The aim of this study was to assess the prevalence of HTLV-1/2 in TB patients in Central-West Brazil and to perform a genetic characterisation of the respective isolates. Of the 402 patients, six (1.49% were positive for anti-HTLV and five (1.24%; 95% confidence interval: 0.46-3.05 were infected with HTLV-1/2. Genetic characterisation demonstrated that the four HTLV-1 isolates belonged to the Transcontinental subgroup A of the Cosmopolitan subtype a and that the HTLV-2 isolate belonged to subtype a (HTLV-2a/c. The prevalence of HTLV infection observed in this study is higher than that observed in local blood donors and the HTLV-1 and 2 subtypes identified are consistent with those circulating in Brazil.

  13. Bolivia. America = Las Americas [Series].

    Toro, Leonor; Avery, Robert S.

    Written for teachers to use with migrant children in elementary grades and to highlight the many Americas, this bilingual English/Spanish social studies resource booklet provides historical and cultural information on Bolivia. A table of contents indicates the language--Spanish or English--in which the topics are written. The quarterly provides an…

  14. Raman and micro-thermometric investigation of the fluid inclusions in quartz in a gold-rich formation from Lepaguare mining district (Honduras, Central America).

    Bersani, D; Salvioli-Mariani, E; Mattioli, M; Menichetti, M; Lottici, P P

    2009-08-01

    Fluid inclusions in the quartz crystals present in gold-rich veins from central Honduras have been studied by means of micro-thermometry and micro-Raman spectroscopy in order to provide information on the physico-chemical conditions and chemical composition of the mineralizing fluids. The use of a confocal micro-Raman apparatus allowed to obtain information on the fluid composition, in particular on the gas phase, minimizing the contributions of the host matrix to the Raman signal. The samples studied were collected from an area (Lepaguare mining district, Northern-Central Honduras) rich in ore deposits due to the Cenozoic magmatic activity, where the gold and sulphide mineralization is connected with a system of quartz veins (few decimetres thick) occurring in low-grade metamorphic rocks and produced by hydrothermal fluids. The quartz crystals present in the gold-rich veins often contain fluid inclusions. Four types of fluid inclusions have been observed, but their assemblage in the same clusters and fracture systems, as well as their comparable salinity and homogenization data, suggest that they have the same origin. Micro-thermometry and Raman spectroscopy provide a composition of the mineralizing fluids attributable to the system H(2)O-NaCl-KCl-CO(2)-CH(4), with temperature and pressure intervals of 210-413 degrees C and 1050-3850 bar, respectively. These data agree with an epigenetic origin of the gold deposit (depth < 6 km) related to granitoid or granodiorite intrusions associated to orogenic environments.

  15. Rapid growth and genetic diversity retention in an isolated reintroduced black bear population in the central appalachians

    Murphy, Sean M.; Cox, John J.; Clark, Joseph D.; Augustine, Benjamin J.; Hast, John T.; Gibbs, Dan; Strunk, Michael; Dobey, Steven

    2015-01-01

    Animal reintroductions are important tools of wildlife management to restore species to their historical range, and they can also create unique opportunities to study population dynamics and genetics from founder events. We used non-invasive hair sampling in a systematic, closed-population capture-mark-recapture (CMR) study design at the Big South Fork (BSF) area in Kentucky during 2010 and Tennessee during 2012 to estimate the demographic and genetic characteristics of the black bear (Ursus americanus) population that resulted from a reintroduced founding population of 18 bears in 1998. We estimated 38 (95% CI: 31–66) and 190 (95% CI: 170–219) bears on the Kentucky and Tennessee study areas, respectively. Based on the Tennessee abundance estimate alone, the mean annual growth rate was 18.3% (95% CI: 17.4–19.5%) from 1998 to 2012. We also compared the genetic characteristics of bears sampled during 2010–2012 to bears in the population during 2000–2002, 2–4 years following reintroduction, and to the source population. We found that the level of genetic diversity since reintroduction as indicated by expected heterozygosity (HE) remained relatively constant (HE(source, 2004) = 0.763, HE(BSF, 2000–2002) = 0.729, HE(BSF, 2010–2012) = 0.712) and the effective number of breeders (NB) remained low but had increased since reintroduction in the absence of sufficient immigration (NB(BSF, 2000–2002) = 12, NB(BSF, 2010–2012)  = 35). This bear population appears to be genetically isolated, but contrary to our expectations, we did not find evidence of genetic diversity loss or other deleterious genetic effects typically observed from small founder groups. We attribute that to high initial genetic diversity in the founder group combined with overlapping generations and rapid population growth. Although the population remains relatively small, the reintroduction using a small founder group appears to be demographically and genetically

  16. Cost-effectiveness analysis of varenicline versus existing smoking cessation strategies in Central America and the Caribbean using the BENESCO model.

    Lutz, Manfred A; Lovato, Pedro; Cuesta, Genaro

    2012-02-01

    In Central American countries, the economic burden of tobacco has not been assessed. In Costa Rica, a study demonstrated that tobacco-related diseases represent high costs for the health care system. The aim of this study was to assess the cost-effectiveness of varenicline compared with other existing strategies for smoking cessation within a 10-year time horizon in an adult population cohort from Central American and Caribbean countries using the health care payer's perspective. The Benefits of Smoking Cessation on Outcomes simulation model was used for an adult cohort in Costa Rica (n = 2 474 029), Panama (n = 2 249 676), Nicaragua (n = 3 639 948), El Salvador (n = 4 537 803), and the Dominican Republic (n = 6 528 125) (N = 19 429 581). Smoking cessation therapies compared were varenicline (0.5-2 mg/day) versus bupropion (300 mg/day), nicotine replacement therapy (5-15 mg/day), and unaided cessation. Effectiveness measures were: life-years (LYs) gained and quality-adjusted life-years (QALYs) gained. Resource use and cost data were obtained from a country's Ministry of Health and/or Social Security Institutions (2008-2010). The model used a 5% discount rate for costs (expressed in 2010 US$) and health outcomes. Probabilistic sensitivity analyses were conducted and acceptability curves were constructed. Varenicline reduced smoking-related morbidity, mortality, and health care costs in each country included in the study. Accumulatively, mortality in the varenicline arm was reduced by 1190, 1538, and 2902 smoking-related deaths compared with bupropion, nicotine replacement therapy, and unaided cessation, respectively. The net average cost per additional quitter showed that varenicline was cost-saving when compared with competing alternatives. Regarding LYs and QALYs gained in 10 years, varenicline obtained the greatest number of QALYs and LYs in each country, while unaided cessation obtained the fewest. Cost-effectiveness analyses in all 5 countries showed that

  17. Bull trout life history, genetics, habitat needs, and limiting factors in Central and Northeast Oregon. Annual report 1996

    Bellerud, B.L.; Gunkel, S.; Hemmingsen, A.R.; Buchanan, D.V.; Howell, P.J.

    1997-10-01

    This study is part of a multi-year research project studying aspects of bull trout life history, ecology and genetics. This report covers the activities of the project in 1996. Results and analysis are presented in the following five areas: (1) analysis of the genetic structure of Oregon bull trout populations; (2) distribution and habitat use of bull trout and brook trout in streams containing both species; (3) bull trout spawning surveys; (4) summary and analysis of historical juvenile bull trout downstream migrant trap catches in the Grande Ronde basin; and (5) food habits and feeding behavior of bull trout alone and in sympatry with brook trout

  18. Bull Trout Life History, Genetics, Habitat Needs, and Limiting Factors in Central and Northeast Oregon. Annual Report 1996.

    Bellerud, Blane L.; Gunckel, Stephanie; Hemmingsen, Alan R.; Buchanan, David V.; Howell, Philip J.

    1997-10-01

    This study is part of a multi-year research project studying aspects of bull trout life history, ecology and genetics. This report covers the activities of the project in 1996. Results and analysis are presented in the following five areas: (1) analysis of the genetic structure of Oregon bull trout populations; (2) distribution and habitat use of bull trout and brook trout in streams containing both species; (3) bull trout spawning surveys; (4) summary and analysis of historical juvenile bull trout downstream migrant trap catches in the Grande Ronde basin; and (5) food habits and feeding behavior of bull trout alone and in sympatry with brook trout.

  19. The cost and cost-effectiveness of childhood cancer treatment in El Salvador, Central America: A report from the Childhood Cancer 2030 Network.

    Fuentes-Alabi, Soad; Bhakta, Nickhill; Vasquez, Roberto Franklin; Gupta, Sumit; Horton, Susan E

    2018-01-15

    Although previous studies have examined the cost of treating individual childhood cancers in low-income and middle-income countries, to the authors' knowledge none has examined the overall cost and cost-effectiveness of operating a childhood cancer treatment center. Herein, the authors examined the cost and sources of financing of a pediatric cancer unit in Hospital Nacional de Ninos Benjamin Bloom in El Salvador, and make estimates of cost-effectiveness. Administrative data regarding costs and volumes of inputs were obtained for 2016 for the pediatric cancer unit. Similar cost and volume data were obtained for shared medical services provided centrally (eg, blood bank). Costs of central nonmedical support services (eg, utilities) were obtained from hospital data and attributed by inpatient share. Administrative data also were used for sources of financing. Cost-effectiveness was estimated based on the number of new patients diagnosed annually and survival rates. The pediatric cancer unit cost $5.2 million to operate in 2016 (treating 90 outpatients per day and experiencing 1385 inpatient stays per year). Approximately three-quarters of the cost (74.7%) was attributed to 4 items: personnel (21.6%), pathological diagnosis (11.5%), pharmacy (chemotherapy, supportive care medications, and nutrition; 31.8%), and blood products (9.8%). Funding sources included government (52.5%), charitable foundations (44.2%), and a social security contribution scheme (3.4%). Based on 181 new patients per year and a 5-year survival rate of 48.5%, the cost per disability-adjusted life-year averted was $1624, which is under the threshold considered to be very cost effective. Treating childhood cancer in a specialized unit in low-income and middle-income countries can be done cost-effectively. Strong support from charitable foundations aids with affordability. Cancer 2018;124:391-7. © 2017 American Cancer Society. © 2017 American Cancer Society.

  20. Does the phenotypic selection affect the genetic structure and diversity? A study case on Walnut in eastern central Italy (the region of Marche

    Fulvio Ducci

    2009-12-01

    Full Text Available The Persian walnut (Juglans regia L. is widely planted in western Europe, either for fruit either for high quality timber production. This tree is generally considered non authoctonous, probably introduced from East some 7000 years ago and spread by several ancient civilisations. The possible artificial origin seems confirmed by the low intra-specific variation and the higher individual variability recorded by several Authors as well as by the lack of natural populations. Indeed, only wider fruit cultivation areas or small groups, lines or isolated walnut trees can be recorded in Italy. The occurrence of walnuts in forest, escaped from cultivation areas, is very rare. Due to the increased interest of planters, walnut plantations have been extended several ten thousands hectares throughout all western Europe. As a consequence of that it was evident the necessity of selected suitable basic populations in order to supply high quality reproductive materials. The conventional method based on the organisation of a wide and exhaustive seed procurement from the native range to establish provenance tests is at the present impossible. Thus it is necessary to study methods of selection which consider basic materials growing within the western European range. This study is aimed to test the efficiency of the multi-trait Selection Index method, in preserving levels of genetic diversity and structures compatible with the standards observed within a reference system of extended Italian populations. As a consequence of the relatively recent introduction, the genetic structure of the species shows individual variation higher than inter-population diversity. Those genetic structure characteristics were revealed also during a survey of walnut resources in the region of Marche, central Italy. The survey was the starting point for selecting and preserving basic materials for high quality woody production, possibly interesting for forest nurseries in the region. The

  1. Biologic and genetic characteristics of Toxoplasma gondii isolates in free-range chickens from Nicaragua, Central America

    Dubey, J.P.; Sundar, N.; Pineda, N.

    2006-01-01

    chickens with titers of 1:5 or less did not shed oocysts. T. gondii was isolated by bioassay in mice from 47 chickens with MAT titers of 1:20 or higher. All infected mice from six isolates died of toxoplasmosis. Overall, 41 of 170 (24.1%) mice that became infected after inoculation with chicken tissues...... died of toxoplasmosis. Genotyping of these 48 isolates (47 from mice and 1 from pooled tissues) using polymorphisms at the loci SAG1, SAG2, SAG3, BTUB and GRA6 revealed eight genotypes. Six isolates had Type I alleles, three isolate had Type II alleles and six isolates had Type III alleles at all loci...

  2. Informing a Learning Progression in Genetics: Which Should Be Taught First, Mendelian Inheritance or the Central Dogma of Molecular Biology?

    Duncan, Ravit Golan; Castro-Faix, Moraima; Choi, Jinnie

    2016-01-01

    The Framework for Science Education and the Next Generation Science Standards in the USA emphasize learning progressions (LPs) that support conceptual coherence and the gradual building of knowledge over time. In the domain of genetics there are two independently developed alternative LPs. In essence, the difference between the two progressions…

  3. Genetic differentiation between introduced Central European sika and source populations in Japan: effects of isolation and demographic events

    Krojerová-Prokešová, Jarmila; Barančeková, Miroslava; Kawata, Y.; Oshida, T.; Igota, H.; Koubek, Petr

    2017-01-01

    Roč. 19, č. 7 (2017), s. 2125-2141 ISSN 1387-3547 R&D Projects: GA ČR GA524/09/1569 Institutional support: RVO:68081766 Keywords : Bottleneck * Founder effect * Genetic diversity * Invasion * Microsatellite loci Subject RIV: EG - Zoology OBOR OECD: Biodiversity conservation Impact factor: 2.473, year: 2016

  4. An integrative study of the genetic, social and environmental determinants of chronic kidney disease characterized by tubulointerstitial damages in the North Central Region of Sri Lanka.

    Nanayakkara, Shanika; Senevirathna, S T M L D; Abeysekera, Tilak; Chandrajith, Rohana; Ratnatunga, Neelakanthi; Gunarathne, E D L; Yan, Junxia; Hitomi, Toshiaki; Muso, Eri; Komiya, Toshiyuki; Harada, Kouji H; Liu, Wanyang; Kobayashi, Hatasu; Okuda, Hiroko; Sawatari, Hideyuki; Matsuda, Fumihiko; Yamada, Ryo; Watanabe, Takao; Miyataka, Hideki; Himeno, Seiichiro; Koizumi, Akio

    2014-01-01

    Previous investigations on chronic kidney disease of unknown etiology characterized by tubulointerstitial damages (CKDu) in the North Central Region (NCR) of Sri Lanka have supported the involvement of social, environmental and genetic factors in its pathogenesis. We conducted a social-environmental-and-genetic epidemiology study on a male population in NCR to investigate the genetic and environmental contributors. We recruited 311 case-series patients and 504 control candidates. Of the 504 control candidates, 218 (43%) were eliminated because of the presence of hypertension, proteinuria, high HbA1c, high serum creatinine or high alpha-1 microglobulin in urine. None of 18 metals measured (μg//) in urine, including Cd, As and Pb, showed significantly higher concentrations in cases compared with controls. As speciation results showed that 75-80% of total urinary As was in the form of arsenobetaine, which is non-toxic to humans. None of the metal concentrations in drinking water samples exceeded guideline values. A genome-wide association study (GWAS) was conducted to determine the genetic contributors. The GWAS yielded a genome-wide significant association with CKDu for a single nucleotide polymorphism (SNP; rs6066043; p=5.23 × 10(-9) in quantitative trait locus analysis; p=3.73 × 10(-9) in dichotomous analysis) in SLC13A3 (sodium-dependent dicarboxylate transporter member 3). The population attributable fraction and odds ratio for this SNP were 50% and 2.13. Genetic susceptibility was identified as the major risk factor for CKDu. However, 43% of the apparently healthy male population suffers from non-communicable diseases, suggesting their possible influence on CKDu progression.

  5. Genetic diversity, evolutionary history and implications for conservation of the lion (Panthera leo) in West and Central Africa

    Bertola, L.D.; Hooft, van W.F.; Vrieling, K.; Weerd, de D.R.U.; York, D.S.; Bauer, H.; Prins, H.H.T.; Funston, P.J.; Haes, de H.A.U.; Leirs, H.; Haeringen, van W.A.; Sogbohossou, E.; Tumenta, P.N.; Iongh, de H.H.

    2011-01-01

    Aim In recent decades there has been a marked decline in the numbers of African lions (Panthera leo), especially in West Africa where the species is regionally endangered. Based on the climatological history of western Africa, we hypothesize that West and Central African lions have a unique

  6. A preserved early Ediacaran magmatic arc at the northernmost portion of the Transversal Zone central subprovince of the Borborema Province, Northeastern South America

    Benjamim Bley de Brito Neves

    Full Text Available ABSTRACT: Magmatic arcs are an essential part of crust-forming events in planet Earth evolution. The aim of this work was to describe an early Ediacaran magmatic arc (ca. 635-580 Ma exposed in the northernmost portion of the Transversal Zone, central subprovince of Borborema Province, northeast Brazil. Our research took advantage of several syntheses by different authors, including theses and dissertations, carried out on magmatic rocks of the study area for the last 30 years. The ca. 750 km long and up to 140 km wide arc, trending ENE-WSW, is preserved to the south of the Patos Lineament, between 35º15' and 42º30'W and 7º15' and 8ºS. About 90 different stocks and batholiths of I-type granitic rocks were mapped along this orogenic zone, preferentially intruding low-grade schists of the Cryogenian-Ediacaran Piancó-Alto Brígida (SPAB belt. Three igneous supersuites are recognized: a epidote-bearing granodiorites and tonalites ("Conceição" type; b high-K calc-alkaline granites ("Itaporanga" type; c biotite granodiorites of trondhjemite affinity ("Serrita" type. A fourth group of peralkalic and shoshonitic rocks occurs to the south of the previous ones, reflecting special tectonic conditions. NNE-SSW trending Paleoproterozoic fold belts, surrounding Archean nuclei, characterize the continental part of the northern lower plate. The oceanic fraction of this lower plate was recycled by subduction and scarce remnants of which may be seen either within the enclosing low-grade schists or as xenoliths within the arc intrusions. The upper continental plate presents WSW-ENE structural trends and is composed of Neoproterozoic fold belts and Paleoproterozoic reworked basement inliers. Available data bear clear evidence of an Ediacaran magmatic arc built at the northern portion of the Transversal Zone in the Borborema Province, northeast Brazil.

  7. Economic and other determinants of infant and child mortality in small developing countries: the case of Central America and the Caribbean.

    Hojman, D E

    1996-03-01

    This analysis involves empirically testing a theoretical model among 22 Central American and Caribbean countries during the 1990s that explains differences in infant and child mortality. Explanatory measures capture demographic, economic, health care, and educational characteristics. The model is expected to allow for an assessment of the potential impact of structural adjustment and external debt. It is pointed out that birth rates and child mortality rates followed similar patterns over time and between countries. In this study's regression analyses all variables in the three models that explain infant mortality are exogenous: low birth weight, immunization, gross domestic product per capita, years of schooling for women, population/nurse, and debt as a proportion of gross national product. As nations became richer, infant mortality declined. Infant mortality was lower in countries with high external debt. In models for explaining the birth rate and the child mortality rate, the best fit included variables for debt, real public expenditure on health care, water supply, and malnutrition. Analysis in a simultaneous model for 10 countries revealed that the birth rate and the child mortality rate were more responsive to shocks in exogenous variables in Barba