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Sample records for centers blood establishment

  1. Oil Reserve Center Established

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Like other countries,China has started to grow its strategic oil reserve in case oil supplies are cut On December 18,2007,the National Development and Reform Commission(NDRC),China’s top economic planner,announced that the national oil reserve center has been officially launched.The supervisory system over the oil reserves has three levels: the energy department of the NDRC,the oil reserve center,and the reserve bases.

  2. Blood Establishment Registration Database

    Data.gov (United States)

    U.S. Department of Health & Human Services — This application provides information for active, inactive, and pre-registered firms. Query options are by FEI, Applicant Name, Establishment Name, Other Names,...

  3. Establishing and evaluating bar-code technology in blood sampling system: a model based on human centered human-centered design method.

    Science.gov (United States)

    Chou, Shin-Shang; Yan, Hsiu-Fang; Huang, Hsiu-Ya; Tseng, Kuan-Jui; Kuo, Shu-Chen

    2012-01-01

    This study intended to use a human-centered design study method to develop a bar-code technology in blood sampling process. By using the multilevel analysis to gather the information, the bar-code technology has been constructed to identify the patient's identification, simplify the work process, and prevent medical error rates. A Technology Acceptance Model questionnaire was developed to assess the effectiveness of system and the data of patient's identification and sample errors were collected daily. The average scores of 8 items users' perceived ease of use was 25.21(3.72), 9 items users' perceived usefulness was 28.53(5.00), and 14 items task-technology fit was 52.24(7.09), the rate of patient identification error and samples with order cancelled were down to zero, however, new errors were generated after the new system deployed; which were the position of barcode stickers on the sample tubes. Overall, more than half of nurses (62.5%) were willing to use the new system.

  4. Distribution of certain drug products by registered blood establishments and comprehensive hemophilia diagnostic treatment centers that qualify as health care entities; Prescription Drug Marketing Act of 1987; Prescription Drug Amendments of 1992; policies, requirements and administrative procedures. Final rule.

    Science.gov (United States)

    2008-10-09

    The Food and Drug Administration (FDA) is amending its regulations to allow certain registered blood establishments and comprehensive hemophilia diagnostic treatment centers that are also health care entities to distribute certain drug products. The final rule amends limited provisions of the regulations implementing the Prescription Drug Marketing Act of 1987 (PDMA), as modified by the Prescription Drug Amendments of 1992 (PDA). These regulations, among other things, restrict the sale, purchase, or trade of, or the offer to sell, purchase, or trade, prescription drugs purchased by hospitals and other health care entities.

  5. Transplant organizational structures: viewpoints from established centers.

    Science.gov (United States)

    Abouljoud, M; Klintmalm, G; Whitehouse, S

    2012-10-01

    This personal viewpoint report summarizes the responses of a survey targeting established transplant programs with a structured framework, such as center, institute, or department, and stability of leadership to assure valuable experiential observations. The 18-item survey was sent to 20 US institutions that met inclusion criteria. The response rate was 100%. Seventeen institutions had a distinct transplant governance structure. A majority of respondents perceived that their type of transplant structure was associated with enhanced recognition within their institution (85%), improved regulatory compliance (85%), transplant volume growth (75%), improved quality outcomes (75%) and increased funding for transplant-related research (75%). The prevailing themes in respondents' remarks were the perceived need for autonomy of the transplant entity, alignment among services and finances and alignment of authority with responsibility. Many respondents suggested that a dialogue be opened about effective transplant infrastructure that overcomes the boundaries of traditional academic department silos.

  6. Establishment of a world food preservation center

    Directory of Open Access Journals (Sweden)

    Wilson Charles L

    2013-01-01

    Full Text Available Abstract A World Food Preservation Center (WFPC is proposed in response to a pending civilization-threatening food shortage and our limited ability to adequately increase food production. Some estimates put losses of food in developing countries after it is produced and before it is consumed at 50%. These losses are particularly threatening to individuals and farmers who are living in the midst of food insecurity. Although numerous organizations have attempted to address this problem worldwide, the magnitude of the effort has not come close to the enormity of the problem. Most of these programs are also short-term and require continuous input by postharvest specialists from developed countries in order to be sustainable. A critical need exists for a substantial and sustainable worldwide program that can significantly reduce losses and waste of food in developing countries. The World Food Preservation Center proposed here meets this need by educating young scientists in developing countries about low-input, appropriate technologies for preserving food postharvest. It also conducts research on postharvest technologies especially suited for application in developing countries such as biological control, solar refrigeration, and coordinated transport and marketing schemes that support and sustain the local production of food commodities.

  7. Asia's First Bat Research Center Established in Beijing

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ In cooperation with a local government, the CAS Institute of Zoology (IOZ) has established Asia's first bat research and protection center in Fangshan, a southwest suburb of Beijing. Its opening ceremony was held on November 16, 2004.

  8. A rational framework for production decision making in blood establishments.

    Science.gov (United States)

    Ramoa, Augusto; Maia, Salomé; Lourenço, Anália

    2012-07-24

    SAD_BaSe is a blood bank data analysis software, created to assist in the management of blood donations and the blood production chain in blood establishments. In particular, the system keeps track of several collection and production indicators, enables the definition of collection and production strategies, and the measurement of quality indicators required by the Quality Management System regulating the general operation of blood establishments. This paper describes the general scenario of blood establishments and its main requirements in terms of data management and analysis. It presents the architecture of SAD_BaSe and identifies its main contributions. Specifically, it brings forward the generation of customized reports driven by decision making needs and the use of data mining techniques in the analysis of donor suspensions and donation discards.

  9. Software Test And Evaluation Center Of CASC Established

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ The software Test and Evaluation Center of CASC(CASC-STEC) was established recently.The establishment of the CASC-STEC is an important measure to strengthen the capability of software test and evaluation,to ensure the quality of software products and improve the level of software engineering.

  10. Establishing a national research center on day care

    DEFF Research Database (Denmark)

    Ellegaard, Tomas

    The paper presents and discusses the current formation of a national research center on ECEC. The center is currently being established. It is partly funded by the Danish union of early childhood and youth educators. It is based on cooperation between a number of Danish universities and this nati...... current new public management policies. However there is also more conflicting issues that emerge in this enterprise – especially on interests, practice relevance and knowledge paradigms....

  11. Establishing a Teaching Support Center at a Land Grant University.

    Science.gov (United States)

    Jackman, Diane H.; Swan, Michael K.

    The Teaching Support Center (TSC) at the University of North Dakota was established in 1992 to provide faculty and graduate assistants with a wide range of pedagogical, professional, and technological assistance in order to improve the quality of instruction. A 3-year plan was developed to implement 13 goals, which are: (1) determining the needs…

  12. INVISTA Establishes Research Center in Mainland China Its First Textile

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    On July 25, 2012, INVISTA announced the opening of its first textile research center in Mainland China, demonstrating its continued commitment to developing high-value, innovative technologies and products. The $7.3 million, 3,000 sqm center is the company's first investment in textile research at such scale in Mainland, China, and the fourth facility of its kind to be established by INVlSTA anywhere in the world. The other three existing facilities are located in the United States, Italy and Taiwan.

  13. ESTABLISHMENT OF THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    Energy Technology Data Exchange (ETDEWEB)

    Hugh W. Rimmer

    2003-07-01

    Technical Progress Report describes progress made on the eight sub-projects awarded in the first year of Cooperative Agreement DE-FC26-01NT41091: Establishment of the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices. Due to the time taken up by the solicitation/selection process, these cover the initial 6-month period of activity only.

  14. Establishment of the Center for Advanced Separation Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Christopher E. Hull

    2006-09-30

    This Final Technical Report covers the eight sub-projects awarded in the first year and the five projects awarded in the second year of Cooperative Agreement DE-FC26-01NT41091: Establishment of the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  15. Quality Assessment of Established and Emerging Blood Components for Transfusion

    Directory of Open Access Journals (Sweden)

    Jason P. Acker

    2016-01-01

    Full Text Available Blood is donated either as whole blood, with subsequent component processing, or through the use of apheresis devices that extract one or more components and return the rest of the donation to the donor. Blood component therapy supplanted whole blood transfusion in industrialized countries in the middle of the twentieth century and remains the standard of care for the majority of patients receiving a transfusion. Traditionally, blood has been processed into three main blood products: red blood cell concentrates; platelet concentrates; and transfusable plasma. Ensuring that these products are of high quality and that they deliver their intended benefits to patients throughout their shelf-life is a complex task. Further complexity has been added with the development of products stored under nonstandard conditions or subjected to additional manufacturing steps (e.g., cryopreserved platelets, irradiated red cells, and lyophilized plasma. Here we review established and emerging methodologies for assessing blood product quality and address controversies and uncertainties in this thriving and active field of investigation.

  16. Quality Assessment of Established and Emerging Blood Components for Transfusion

    Science.gov (United States)

    Marks, Denese C.

    2016-01-01

    Blood is donated either as whole blood, with subsequent component processing, or through the use of apheresis devices that extract one or more components and return the rest of the donation to the donor. Blood component therapy supplanted whole blood transfusion in industrialized countries in the middle of the twentieth century and remains the standard of care for the majority of patients receiving a transfusion. Traditionally, blood has been processed into three main blood products: red blood cell concentrates; platelet concentrates; and transfusable plasma. Ensuring that these products are of high quality and that they deliver their intended benefits to patients throughout their shelf-life is a complex task. Further complexity has been added with the development of products stored under nonstandard conditions or subjected to additional manufacturing steps (e.g., cryopreserved platelets, irradiated red cells, and lyophilized plasma). Here we review established and emerging methodologies for assessing blood product quality and address controversies and uncertainties in this thriving and active field of investigation. PMID:28070448

  17. Quality Assessment of Established and Emerging Blood Components for Transfusion.

    Science.gov (United States)

    Acker, Jason P; Marks, Denese C; Sheffield, William P

    2016-01-01

    Blood is donated either as whole blood, with subsequent component processing, or through the use of apheresis devices that extract one or more components and return the rest of the donation to the donor. Blood component therapy supplanted whole blood transfusion in industrialized countries in the middle of the twentieth century and remains the standard of care for the majority of patients receiving a transfusion. Traditionally, blood has been processed into three main blood products: red blood cell concentrates; platelet concentrates; and transfusable plasma. Ensuring that these products are of high quality and that they deliver their intended benefits to patients throughout their shelf-life is a complex task. Further complexity has been added with the development of products stored under nonstandard conditions or subjected to additional manufacturing steps (e.g., cryopreserved platelets, irradiated red cells, and lyophilized plasma). Here we review established and emerging methodologies for assessing blood product quality and address controversies and uncertainties in this thriving and active field of investigation.

  18. Ovine blood: establishment of a list of reference values relevant for blood coagulation in sheep.

    Science.gov (United States)

    Wilhelmi, Mathias H; Tiede, Andreas; Teebken, Omke E; Bisdas, Theodosios; Haverich, Axel; Mischke, Reinhard

    2012-01-01

    Ovine animal models are widely used to conduct preclinical studies, e.g., to evaluate cardiovascular prostheses intended to be applied in man. However, although analyzed in many of those studies, information about ovine blood reference values is scanty. The aim of this study is to establish a reference list of ovine blood parameters relevant for blood coagulation. A cohort of 47 mature ewes was evaluated. Parameters comprised the following: cells and cellular components-platelet, red, and white cell counts (including subsets), hemoglobin (Hb), hematocrit (HCT), mean corpuscular hemoglobin (MCH) and mean corpuscular volume (MCV), and MCH concentration (MCHC); global tests of coagulation-prothrombin time (Quick's time) and activated partial thromboplastin time (aPTT); and parameters relevant for blood coagulation-fibrinogen, antithrombin (AT), and von Willebrand Factor. After explorative data analysis, a list of ovine reference values was established. Interestingly, a comparison with human reference values revealed some interspecies differences between sheep and man, i.e., much higher ovine ranges for some cell counts (neutrophils, lymphocytes, basophils, eosinophils, and platelets) but lower values for some other parameters (Hb, HCT, MCV, MCH, AT, and Quick's test). We established a reference list of ovine blood count and blood coagulation parameters. Because of some peculiarities of the ovine blood, this list may have implications for the interpretation of experimental data.

  19. 78 FR 18353 - Guidance for Industry: Blood Establishment Computer System Validation in the User's Facility...

    Science.gov (United States)

    2013-03-26

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry: Blood Establishment Computer System... ``Guidance for Industry: Blood Establishment Computer System Validation in the User's Facility'' dated April... establishment computer system validation program, consistent with recognized principles of software...

  20. Differences between hospital- and community-acquired blood exposure incidents revealed by a regional expert counseling center.

    NARCIS (Netherlands)

    Wijk, P.T. van; Pelk-Jongen, M.; Boer, E. de; Voss, A.; Wijkmans, C.; Schneeberger, P.M.

    2006-01-01

    OBJECTIVE: One year (2003) regional analysis of all blood exposure incidents from hospitals as well as from the community. DESIGN: Establishment of an easily accessible regional expert counseling center, operating 24 h a day, for all accidental blood exposures. Tasks of the center were to register i

  1. Expanding role of a blood center

    Directory of Open Access Journals (Sweden)

    Jaisy Mathai

    2012-01-01

    Full Text Available Materials and Methods: The study was performed on prospective donors who reported to the Department of Transfusion Medicine. Individuals deferred due to hypertension contributed the study population. They were compared with age and sex matched donor controls. Demographic details were recorded in a proforma. On identification of a hypertensive individual, consequent two comparable donors were taken as controls with a total of 50 hypertensive subjects. Hypertensive status of the subjects were assessed based on the criteria formulated by the WHO-ISH and US Seventh Joint National Committee report on prevention, detection, evaluation and treatment of high blood pressure. Results: About 0.95% of healthy blood donors had undetected hypertension. Mean age at detection of hypertension in the study group was 35.44 ± 7.69 years. Higher BMI was observed in the hypertensive group compared to normotensive control group with P value significant at 0.0001. Conclusion: About 1% of healthy individuals were found to have undetected hypertension. Though the study was not designed to determine the prevalence of hypertension in the region, it is a rough estimate of the proportion of undetected hypertension in the local population as donors are considered as representative of healthy population.

  2. 77 FR 12981 - Establishment of the Interagency Trade Enforcement Center

    Science.gov (United States)

    2012-03-05

    ..., detailed to the Center and reporting to the Director. The Center shall also have an Intelligence Community... exports and ensuring U.S. workers, businesses, ranchers, and farmers are able to compete on a level... eliminate foreign trade barriers and unfair foreign trade practices to ensure that U.S. workers,...

  3. PetroChina to Establish Command Center on Oil Dispatch

    Institute of Scientific and Technical Information of China (English)

    Zhang Desin

    2008-01-01

    @@ PetroChina will install a command center on the distribution of refined oil products in 2008 to improve supply efficiency amidst oil shortage. The center with its layout designed by the China Petroleum and Petrochemical Engineering Institute has entered feasibility study, and may be put to use in August at the earliest,according to the recent reports from China news media.

  4. [How do I assess requirement of a blood bank and its kind for a healthcare establishment?].

    Science.gov (United States)

    Lafeuillade, B; Tixier, A; Bliem, C; Meyer, F

    2014-12-01

    Access to blood components is required for healthcare establishments, particularly for emergency situation and hospital blood bank was often a response to this requirement. However, the complexity of regulation and economic pressures lead healthcare establishment to review regularly their need for a blood bank. This assessment requires analysis of need for transfusions in terms of delay, quantity and clinical situations to which they must respond. When a blood bank is required, three kinds could be under consideration: emergency blood bank, intermediate blood bank and issuance blood bank. According to requirements, advantages and disadvantages of each kind, healthcare establishments would select the most suitable one.

  5. Establishment of the Center for Biomedical Technology Innovation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-12-15

    The report discussed the following topics: (1) Orthopedic Devices; (2) Hybrid Vector and Method Resulting in Protein Overproduction by Eukaryotic Cells; (3) Surgical Simulator; (4) CBTI (Center for Biomedical Technology Innovation) as an Incubator for Start-up Companies; (5) Voice-activated, computer-assisted surgical robotics; (6) Through transmission ultrasonic 3-D holography for diagnostic imaging; (7) CBTI's Scibermed{trademark} Virtual Institute (SVI); and (8) Laser Oxygenation Tomography.

  6. Tianjin Normal University Establishes Women’s Studies Center

    Institute of Scientific and Technical Information of China (English)

    1994-01-01

    IN July, 1993, an international seminar titled "Chinese Women and Development—Status, Health and Employment" was sponsored by the Women’s Studies Center at Tianjin Normal University. More than 100 international and domestic specialists and workers who deal with women’s issues attended. At the conference, the Women’s Research Institute of the All-China Women’s Federation disclosed the results of an investigation about the status of women in China, which was launched in the early 1990s on a nationwide scale. The results showed that China’s economic reform has greatly affected women. As a result, many researchers who began their research by considering China’s present economic situation, tried to determine the influences the state’s

  7. Establishing the diffuse correlation spectroscopy signal relationship with blood flow.

    Science.gov (United States)

    Boas, David A; Sakadžić, Sava; Selb, Juliette; Farzam, Parisa; Franceschini, Maria Angela; Carp, Stefan A

    2016-07-01

    Diffuse correlation spectroscopy (DCS) measurements of blood flow rely on the sensitivity of the temporal autocorrelation function of diffusively scattered light to red blood cell (RBC) mean square displacement (MSD). For RBCs flowing with convective velocity [Formula: see text], the autocorrelation is expected to decay exponentially with [Formula: see text], where [Formula: see text] is the delay time. RBCs also experience shear-induced diffusion with a diffusion coefficient [Formula: see text] and an MSD of [Formula: see text]. Surprisingly, experimental data primarily reflect diffusive behavior. To provide quantitative estimates of the relative contributions of convective and diffusive movements, we performed Monte Carlo simulations of light scattering through tissue of varying vessel densities. We assumed laminar vessel flow profiles and accounted for shear-induced diffusion effects. In agreement with experimental data, we found that diffusive motion dominates the correlation decay for typical DCS measurement parameters. Furthermore, our model offers a quantitative relationship between the RBC diffusion coefficient and absolute tissue blood flow. We thus offer, for the first time, theoretical support for the empirically accepted ability of the DCS blood flow index ([Formula: see text]) to quantify tissue perfusion. We find [Formula: see text] to be linearly proportional to blood flow, but with a proportionality modulated by the hemoglobin concentration and the average blood vessel diameter.

  8. The potential of RFID technology in Blood Center processes.

    Science.gov (United States)

    Kebo, V; Klement, P; Cermáková, Z; Gottfried, J; Sommerová, M; Palecek, A

    2010-01-01

    Current RFID technology deployment is limited by safety, procedural and physical limitations in healthcare field. It is important to define and ensure safe operation of technologies without actual deployment in real operation. Potential problems could arise due to the consequences of technical and physical characteristics of RFID technology and its improper location. This article deals with manipulation of blood products and the definition of suitable places for radio identification. Each suitable place must undergo laboratory experiments and tests. The results can provide a convenient base for defining efficient and safe deployment of RFID technology in Blood Centers with substantial financial savings for Czech healthcare.

  9. Establishing a Secure Data Center with Remote Access: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Gonder, J.; Burton, E.; Murakami, E.

    2012-04-01

    Access to existing travel data is critical for many analysis efforts that lack the time or resources to support detailed data collection. High-resolution data sets provide particular value, but also present a challenge for preserving the anonymity of the original survey participants. To address this dilemma of providing data access while preserving privacy, the National Renewable Energy Laboratory and the U.S. Department of Transportation have launched the Transportation Secure Data Center (TSDC). TSDC data sets include those from regional travel surveys and studies that increasingly use global positioning system devices. Data provided by different collecting agencies varies with respect to formatting, elements included and level of processing conducted in support of the original purpose. The TSDC relies on a number of geospatial and other analysis tools to ensure data quality and to generate useful information outputs. TSDC users can access the processed data in two different ways. The first is by downloading summary results and second-by-second vehicle speed profiles (with latitude/longitude information removed) from a publicly-accessible website. The second method involves applying for a remote connection account to a controlled-access environment where spatial analysis can be conducted, but raw data cannot be removed.

  10. 33 CFR 55.11 - How are child development center fees established?

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false How are child development center... HOMELAND SECURITY PERSONNEL CHILD DEVELOPMENT SERVICES General § 55.11 How are child development center fees established? (a) Fees for the provision of services at child development centers shall be set...

  11. An examination of blood center structure and hospital customer satisfaction: what can centralized and decentralized blood centers learn from each other?

    Science.gov (United States)

    Carden, Robert; DelliFraine, Jami L

    2005-01-01

    The cost of blood and blood products has increased rapidly over the last several years while the supply of available blood donors has simultaneously decreased. Higher blood costs and donor shortages have put a strain on the relationship between blood suppliers and their hospital customers. This study examines the association between blood center centralization or decentralization and several aspects of hospital satisfaction. Centralized and decentralized blood centers have significant differences in various aspects of hospital customer satisfaction. Advantages and disadvantages of the two structures are discussed, as well as areas for future research.

  12. 21 CFR 607.7 - Establishment registration and product listing of blood banks and other firms manufacturing human...

    Science.gov (United States)

    2010-04-01

    ... blood banks and other firms manufacturing human blood and blood products. 607.7 Section 607.7 Food and... Provisions § 607.7 Establishment registration and product listing of blood banks and other firms... permit any blood bank or similar establishment to ship blood products in interstate commerce. (b)...

  13. A Study to Determine the Feasibility of Establishing a Wellness Center at Martin Army Community Hospital

    Science.gov (United States)

    1987-11-06

    MTF) establish a Wellness/Health Promotion Center to provide the services needed to support the wellness concepto (Department of the Army, 1984). 2...Directive 1010.10 (Health Promotion). 6. It is recommended that a marketing plan be developed for the wellness center. The plan should include articles for...1981). Wellness programs attract new markets for hospitals. Hospitals, 55(22), 115-116, 119. Manring, S.L. (1985). Evaluating corporate wellness and

  14. Importance of monitoring family members in establishing sources and pathways of lead in blood.

    Science.gov (United States)

    Gulson, B L; Mizon, K J; Korsch, M J; Howarth, D

    1996-10-11

    High precision lead isotope measurements were undertaken to establish the sources and pathways in blood and environmental samples of five families from the Broken Hill lead mining community, New South Wales, Australia. The five families were selected from 27 families investigated to illustrate the different sources and pathways of lead into blood and the importance of monitoring the whole family. The results illustrate that although the major source of lead is from the orebody, paint and petrol can be significant contributors to both house dust and blood leads. The results also show that the sources and pathways can be from the father's occupation and hence monitoring of families is important, especially in high risk locations. In two cases, the elevated blood leads in the children did not derive from their current residence but from other residences in the community.

  15. Establishment of a molecular tool for blood meal identification in Malaysia

    Institute of Scientific and Technical Information of China (English)

    Ernieenor Faraliana Che Lah; Mariana Ahamad; Mohd Subail Haron; Ho Tze Ming

    2012-01-01

    Objective: To establish a polymerase chain reaction (PCR) technique based on cytochrome b (cytb) gene of mitochondria DNA (mtDNA) for blood meal identification. Methods: The PCR technique was established based on published information and validated using blood sample of laboratory animals of which their whole gene sequences are available in GenBank. PCR was next performed to compile gene sequences of different species of wild rodents. The primers used were complementary to the conserved region of the cytb gene of vertebrate’s mtDNA. A total of 100 blood samples, both from laboratory animals and wild rodents were collected and analyzed. The obtained unknown sequences were compared with those in the GenBank database using BLAST program to identify the vertebrate animal species. Results: Gene sequences of 11 species of wild animals caught in 9 localities of Peninsular Malaysia were compiled using the established PCR. The animals involved were Rattus (rattus) tanezumi, Rattus tiomanicus, Leopoldamys sabanus,Tupaia glis, Tupaia minor, Niviventor cremoriventor, Rhinosciurus laticaudatus, Callosciurus caniseps, Sundamys muelleri, Rattus rajah and Maxomys whiteheadi. The BLAST results confirmed the host with exact or nearly exact matches (>89% identity). Ten new gene sequences have been deposited in GenBank database since September 2010. Conclusions: This study indicates that the PCR direct sequencing system using universal primer sets for vertebrate cytb gene is a promising technique for blood meal identification.

  16. FEASIBILITY STUDY OF ESTABLISHING AN ARTIFICIAL INSEMINATION (AI CENTER FOR CARABAOS IN SAN ILDEFONSO, BULACAN, PHILIPPINES

    Directory of Open Access Journals (Sweden)

    F.Q. Arrienda II

    2014-10-01

    Full Text Available The productivity of the carabao subsector is influenced by several constraints such as social,technical, economic and policy factors. The need to enhance the local production of carabaos will helplocal farmers to increase their income. Thus, producing thorough breeds of carabaos and improving itgenetically is the best response to these constraints. This study was conducted to present the feasibilitystudy of establishing an Artificial Insemination (AI Center and its planned area of operation in Brgy.San Juan, Ildefonso, Bulacan. The market, production, organizational and financial viability of operatingthe business would also be evaluated. This particular study will provide insights in establishing an AICenter. Included in this study is the identification of anticipated problems that could affect the businessand recommendation of specific courses of action to counteract these possible problems. Primary datawere obtained through interviews with key informants from the Philippine. Carabao Center (PCC. Togain insights about the present status of an AI Center, interviews with the technicians of PCC and privatefarm were done to get additional information. Secondary data were acquired from various literatures andfrom San Ildefonso Municipal Office. The proposed area would be 1,500 square meters that would beallotted for the laboratory and bullpen. The AI Center will operate six days a week and will be openedfrom 8 AM until 5 PM. However, customers or farmers can call the technicians beyond the office hoursin case of emergency. The total initial investment of Php 3,825,417.39 is needed in establishing the AICenter. The whole amount will be sourced from the owner’s equity. Financial projection showed an IRRof 30% with a computed NPV of Php 2,415,597.00 and a payback period of 3.97 years. Based on all themarket, technical, organizational, financial factors, projections and data analysis, it is said that thisbusiness endeavor is viable and feasible.

  17. First optical education center in Japan established by cooperation between academia and industry

    Science.gov (United States)

    Yatagai, Toyohiko

    2014-07-01

    At the present of the 21st century, optical technology became what must be in our life. If there is no optical technology, we cannot use optical equipments such as the camera, microscopes, DVD, LEDs and laser diodes (LDs). Optics is also the leading part in the most advanced scientific field. It is clear that the organization which does education and research is required in such a very important area. Unfortunately, there was no such organization in Japan. The education and research of light have been individually done in various faculties of universities, various research institutes, and many companies. However, our country is now placed in severer surroundings, such as the globalization of our living, the accelerated competition in research and development. This is one of the reasons why Utsunomiya University has established Center for Optical Research and Education (CORE) in 2007. To contribute to optical technology and further development of optical industry, "Center for Optical Research and Education (CORE), Utsunomiya University" promotes education and research in the field of the optical science and technology cooperatively with industry, academia and the government. Currently, 6 full professors, 21 cooperative professors, 2 visiting professors and 7 post-doctoral researchers and about 40 students are joined with CORE. Many research projects with industries, the local government of Tochigi as well as Japanese government. Optical Innovation Center has established in CORE by supporting of Japan Science and Technology Agency in 2011 to develop advanced optical technologies for local companies.

  18. The importance of establishing an international network of tissue banks and regional tissue processing centers.

    Science.gov (United States)

    Morales Pedraza, Jorge

    2014-03-01

    During the past four decades, many tissue banks have been established across the world with the aim of supplying sterilized tissues for clinical use and research purposes. Between 1972 and 2005, the International Atomic Energy Agency supported the establishment of more than sixty of these tissue banks in Latin America and the Caribbean, Asia and the Pacific, Africa and Eastern Europe; promoted the use of the ionizing radiation technique for the sterilization of the processed tissues; and encouraged cooperation between the established tissue banks during the implementation of its program on radiation and tissue banking at national, regional and international levels. Taking into account that several of the established tissue banks have gained a rich experience in the procurement, processing, sterilization, storage, and medical use of sterilized tissues, it is time now to strengthen further international and regional cooperation among interested tissue banks located in different countries. The purpose of this cooperation is to share the experience gained by these banks in the procurement, processing, sterilization, storage, and used of different types of tissues in certain medical treatments and research activities. This could be done through the establishment of a network of tissue banks and a limited number of regional tissue processing centers in different regions of the world.

  19. Quality indicators for discarding blood in the National Blood Center, Kuala Lumpur

    Directory of Open Access Journals (Sweden)

    Mohammed Morish

    2012-01-01

    Full Text Available Background and Objective: The implementation of quality system and continuous evaluation of all activities of the Blood Transfusion Services (BTS can help to achieve the maximum quantity and quality of safe blood. Optimizing blood collection and processing would reduce the rate of discard and improve the efficiency of the BTS. The objective of this study is to determine the rate of discard of blood and blood component and identify its reasons at the National Blood Centre (NBC, Kuala Lumpur, during the year of 2007 in order to introduce appropriate intervention. Study Designs and Methods: Data on the number of discarded whole blood units and its components, reasons for discard, and the number of blood components processed as well as the number of collected blood units were obtained from the Blood Bank Information System - NBC database. These were analyzed. Results: The total number of blood units collected in 2007 was 171169 from which 390636 units of components were prepared. The total number of discarded whole blood units and its components was 8968 (2.3%. Platelet concentrate recorded the highest of discard at 6% (3909 followed by whole blood at 3.7% (647, fresh frozen plasma (FFP at 2.5% (2839, and cryoprecipitate at 2% (620. The rate of discarded packed red blood cells RBCs, plasma aphaeresis, and PLT aphaeresis was less than 1% at 0.6% (902, 0.6% (37, and 0.29% (14, respectively. RBC contamination of PLT and plasma were the major cause of discard at 40% (3558. Other causes include leakage (26% - 2306, lipemia (25% - 2208, and underweight (4% - 353. Conclusion: Good donor selection, training and evaluation of the staff, as well as implementation of automation will help to improve processes and output of BTS. This would reduce discard of blood components and wastage caused by non conformance.

  20. A switch from low to high Shh activity regulates establishment of limb progenitors and signaling centers.

    Science.gov (United States)

    Zhulyn, Olena; Li, Danyi; Deimling, Steven; Vakili, Niki Alizadeh; Mo, Rong; Puviindran, Vijitha; Chen, Miao-Hsueh; Chuang, Pao-Tien; Hopyan, Sevan; Hui, Chi-chung

    2014-04-28

    The patterning and growth of the embryonic vertebrate limb is dependent on Sonic hedgehog (Shh), a morphogen that regulates the activity of Gli transcription factors. However, Shh expression is not observed during the first 12 hr of limb development. During this phase, the limb bud is prepatterned into anterior and posterior regions through the antagonistic actions of transcription factors Gli3 and Hand2. We demonstrate that precocious activation of Shh signaling during this early phase interferes with the Gli3-dependent specification of anterior progenitors, disturbing establishment of signaling centers and normal outgrowth of the limb. Our findings illustrate that limb development requires a sweet spot in the level and timing of pathway activation that allows for the Shh-dependent expansion of posterior progenitors without interfering with early prepatterning functions of Gli3/Gli3R or specification of anterior progenitors.

  1. Reference values of fetal erythrocytes in maternal blood during pregnancy established using flow cytometry.

    Science.gov (United States)

    de Wit, Harry; Nabbe, Karin C A M; Kooren, Jurgen A; Adriaansen, Henk J; Roelandse-Koop, Elianne A; Schuitemaker, Joost H N; Hoffmann, Johannes J M L

    2011-10-01

    The aim of our study was to assess the fetal RBC count in maternal blood during uncomplicated pregnancies from 26 weeks onward. We used a flow cytometric method specifically designed for use in a routine hematology analyzer. Pregnant women were recruited through midwives. The participating laboratories used the FMH QuikQuant method (Trillium Diagnostics, Brewer, ME) in a CELL-DYN Sapphire hematology analyzer (Abbott Diagnostics, Santa Clara, CA). The method is based on a monoclonal antibody to hemoglobin F. Flow cytometric data were analyzed by 2 independent observers. The 95th percentile reference range was estimated according to Clinical and Laboratory Standards Institute guidelines. A total of 236 samples were statistically analyzed. Gestational ages ranged from 21.6 to 41 weeks (mean, 32.0 weeks), and the fetal RBC count in maternal blood ranged from 0.00% to 0.50% (median, 0.025%). The fetal RBC count in maternal blood shows no correlation with gestational age. The established reference range during normal pregnancy is less than 0.125%.

  2. Development of a telecare system based on ZigBee mesh network for monitoring blood pressure of patients with hemodialysis in health care centers.

    Science.gov (United States)

    Du, Yi-Chun; Lee, You-Yun; Lu, Yun-Yuan; Lin, Chia-Hung; Wu, Ming-Jei; Chen, Chung-Lin; Chen, Tainsong

    2011-10-01

    In Taiwan, the number of the patients needing dialysis increases rapidly in recent years. Because there is risk in every hemodialysis session, monitoring physiological status, such as blood pressure measurement every 30 min to 1 h is needed during about 4 h hemodialysis process. Therefore, an assisted measurement on blood pressure is needful in dialysis care centers. Telecare system (TCS) is regarded as one of important technique in the medical care. In this study, we utilized ZigBee wireless technique to establish a mesh network for monitoring blood pressure automatically and data storage in medical record system for display and further analysis. Moreover, while the blood pressure exceeds the normal range, the system could send a warning signal to remind, or inform the relatives and clinicians in health care center through the personal handy-phone system (PHS) immediately. The proposed system provides an assisted device for monitoring patients' blood pressure during hemodialysis process and saving medical manpower.

  3. Relation between Cord Blood Mercury Levels and Early Child Development in a World Trade Center Cohort

    OpenAIRE

    Lederman, Sally Ann; Jones, Robert L.; Caldwell, Kathleen L.; Rauh, Virginia; Sheets, Stephen E.; Tang, Deliang; Viswanathan, Sheila; Becker, Mark; Stein, Janet L.; Wang, Richard Y; Perera, Frederica P.

    2008-01-01

    Objective This study was designed to determine whether prenatal mercury exposure, including potential releases from the World Trade Center (WTC) disaster, adversely affects fetal growth and child development. Methods We determined maternal and umbilical cord blood total mercury of nonsmoking women who delivered at term in lower Manhattan after 11 September 2001, and measured birth outcomes and child development. Results Levels of total mercury in cord and maternal blood were not significantly...

  4. [Molecular mechanism for the establishment of blood-vessel gateway for immune cells in the CNS.

    Science.gov (United States)

    Murakami, Masaaki

    2017-01-01

    We have been studying about the molecular mechanism responsible for the establishment of the blood-vessel gateway through which immune cells enter the CNS. We have discovered three kinds of gateways in a multiple sclerosis model, EAE, based on the neural stimulations and named them the gravity-gateway reflex, electric-gateway reflex, and pain-gateway reflex, respectively. All gateway reflexes are involved in specific crosstalk between sensory-sympathetic pathways. For example, in the gravity-gateway reflex, gravity-mediated sensory stimulation via the soleus muscles activates fifth lumber(L5)dorsal loot ganglions to activate L5 sympathetic ganglions, which express norepinephrine at specific vessels of the L5 cord. We explain these three types of gateway reflexes in this chapter.

  5. Evaluation of blood pressure measurement and agreement in an academic health sciences center.

    Science.gov (United States)

    Minor, Deborah S; Butler, Kenneth R; Artman, Katherine L; Adair, Cathy; Wang, Wanmei; McNair, Valerie; Wofford, Marion R; Griswold, Michael

    2012-04-01

    The authors assessed the process of blood pressure (BP) measurement and level of adherence to recommended procedures at representative sites throughout a large academic health sciences center. A casual observer assessed the setting and observed the process, noting the equipment, technique, and BP recorded by site personnel. A trained observer then repeated the patient's BP measurement following American Heart Association recommendations. Significant biases were observed between measurements by site personnel and the trained observer. Site personnel reported on average an increased systolic BP (SBP) of 5.66 mm Hg (95% confidence interval [CI], 3.09-8.23; P<.001) and a decreased diastolic BP (DBP) of -2.96 mm Hg (95% CI, -5.05 to -0.87; P=.005). Overall, 41% of patients had a ≥10-mm Hg difference in SBP between measurements. Similarly, 54% had differences of ≥5 mm Hg in DBP between measurements. Inaccurate BP measurement and poor technique may lead to misclassification, misdiagnosis, and inappropriate medical decisions. Concordance of measured SBP between our site personnel and trained observer was less than optimal. Several areas for improvement were identified. Routine calibration and use of system-wide standardized equipment, establishment of BP measurement protocols, and periodic technique and equipment recertification can be addressed in future quality initiatives.

  6. Bypassing the blood-brian barrier using established skull base reconstruction techniques

    Institute of Scientific and Technical Information of China (English)

    Marcel M.Miyake; Benjamin S.Bleier

    2015-01-01

    Background: Neurological disorders represent a profound healthcare problem accounting for 6.3% of the global disease burden.Alzheimer's disease alone is expected to impact over 115 million people worldwide by 2050 with a cost of over $1 trillion per year to the U.S.economy.Despite considerable advances in our understanding of the pathogenesis and natural history of neurological disorders, the development of disease modifying therapies have failed to keep pace.This lack of effective treatments is directly attributable to the presence of the blood-brain and blood-cerebrospinal fluid barriers (BBB and BCSFB) which prevent up to 98% of all potential neuropharmaceutical agents from reaching the central nervous system (CNS).These obstacles have thereby severely limited research and development into novel therapeutic strategies for neurological disease.Current experimental methods to bypass the BBB, including pharmacologic modification and direct transcranial catheter implantation, are expensive, are associated with significant complications, and cannot be feasibly scaled up to meet the chronic needs of a large, aging patient population.Transmucosal drug delivery: An innovative method of direct CNS drug delivery using heterotopic mucosal grafts was described.This method is based on established endoscopic skull base nasoseptal flap reconstruction techniques.The model has successfully demonstrated CNS delivery of chromophore-tagged molecules 1000 times larger than those typically permitted by the BBB.Conclusions: This innovative technique represents the first described method of permanently bypassing the blood-brain barrier using purely autologous tissues.This has the potential to dramatically improve the current treatment of neurological disease by providing a safe and chronic transnasaldelivery pathway for high molecular weight neuropharmaceuticals.

  7. Microfiche/Telex Oriented Document Services Center Established in Sylvania Library Through Cooperative Test Program with Defense Documentation Center.

    Science.gov (United States)

    Little, Dean K.

    In a cooperative program with Defense Documentation Center Headquarters, Sylvania arranged for procurement of 70,000 unclassified-unlimited documents without DDC Form I cards and 30,000 unclassified-limited and classified documents with Form I's. This was done in order to overcome effects of an in-house documents inventory/selective destruction…

  8. Establishment of a National Wind Energy Center at University of Houston

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Su Su [Univ. of Houston, TX (United States)

    2016-10-31

    The DOE-supported project objectives are to: establish a national wind energy center (NWEC) at University of Houston and conduct research to address critical science and engineering issues for the development of future large MW-scale wind energy production systems, especially offshore wind turbines. The goals of the project are to: (1) establish a sound scientific/technical knowledge base of solutions to critical science and engineering issues for developing future MW-scale large wind energy production systems, (2) develop a state-of-the-art wind rotor blade research facility at the University of Houston, and (3) through multi-disciplinary research, introducing technology innovations on advanced wind-turbine materials, processing/manufacturing technology, design and simulation, testing and reliability assessment methods related to future wind turbine systems for cost-effective production of offshore wind energy. To achieve the goals of the project, the following technical tasks were planned and executed during the period from April 15, 2010 to October 31, 2014 at the University of Houston: (1) Basic research on large offshore wind turbine systems (2) Applied research on innovative wind turbine rotors for large offshore wind energy systems (3) Integration of offshore wind-turbine design, advanced materials and manufacturing technologies (4) Integrity and reliability of large offshore wind turbine blades and scaled model testing (5) Education and training of graduate and undergraduate students and post- doctoral researchers (6) Development of a national offshore wind turbine blade research facility The research program addresses both basic science and engineering of current and future large wind turbine systems, especially offshore wind turbines, for MW-scale power generation. The results of the research advance current understanding of many important scientific issues and provide technical information for solving future large wind turbines with advanced design

  9. Comparative study of Treponemal and non-Treponemal test for screening of blood donated at a blood center

    Directory of Open Access Journals (Sweden)

    Narinder Kaur Naidu

    2012-01-01

    Full Text Available The non-Treponemal tests such as Rapid Plasma Reagin test (RPR or the Venereal Disease Reference Laboratory test are the most commonly used test for screening of syphilis in the blood centers in India. Now, with the availability of Enzyme-linked immunosorbent assay (ELISA and Immunochromatographic assays in the market, we decided to evaluate these assays in comparison with Treponema pallidum Haemagglutination Assay (TPHA which was considered as a gold standard for this study. A total of 8 685 samples of voluntary blood donors were tested on Trepolisa 3.0 and then the initially reactive samples were retested in duplicate on the same assay as well as on Omega Pathozyme, RPR, RAPHA (Rapid Anti-Treponema pallidum Assay, and TPHA. Of the 158 initially reactive samples, 104 were repeatedly reactive on the same assay, 85 were reactive with RPR, 77 were reactive with RAPHA, 60 were reactive on Omega, and 53 were confirmed reactive on TPHA. 48 (56.4% of the results on RPR were biological false positive, while 21.9% of results were false negative on RPR. We evaluated that Omega Pathozyme was quite in agreement with TPHA as compared with Trepolisa 3.0, RAPHA, and RPR. We concluded that Omega Pathozyme (ELISA can be considered as a suitable test for screening of syphilis in a blood center.

  10. Effect of Contraceptive Agents to Women Blood Pressure in Wonogiri Community Health Centers

    Directory of Open Access Journals (Sweden)

    Tanti A. Sujono

    2013-06-01

    Full Text Available The purpose of this study to determine the effect of the use of hormonal contraceptives (injections and pills against increasing of blood pressure on women KB acceptors at the Wonogiri public health center in Wonogiri regency. This research is non-experimental (observational with cross sectional design. The sampling with purposive sampling to acceptors who come to the public health center Wonogiri I and II to conduct KB. Data were collected from 29 acceptors injection, 22 acceptors pill and 34 acceptors IUD (nonhormonal contraception as a control. The data were taken from the acceptors status card, questionnaires and direct interviews with them. The data were analyzed the prevalence ratio of the increase in blood pressure. The result calculation of Prevalence Ratio (PR>1, it indicated that the hormonal contraceptive (injection and pill as a risk factor the occurence of increased blood pressure at hormonal KB acceptors, about 2,93 and 3,61 times consecutively compared to IUD. This suggests that hormonal contraseptive containing a combination of estrogen and progesterone causes an increase in blood pressure, although still within the normal range of blood pressure (<140 mmHg.

  11. Prevalence of Chagas disease in blood donors at the Uberaba Regional Blood Center, Brazil, from 1995 to 2009

    Directory of Open Access Journals (Sweden)

    Laryssa Manso de Lima

    2012-12-01

    Full Text Available INTRODUCTION: A retrospective study was conducted to assess the occurrence of blood donations that were ineligible due to Chagas disease infection from 1995 to 2009 at the Uberaba Regional Blood Center (HRU, Brazil, verify the tendency of this ineligibility, and describe the epidemiologic profile of the donors. METHODS: Retrospective studies of serological ineligibility due to Chagas disease, statistical analysis by means of the chi-square test and odds ratio, study of the tendencies using a dispersion graph and the linear correlation coefficient (r were performed. RESULTS: In the period under study, a 0.2% serum prevalence of ineligibility due to Chagas disease was found, with a significant drop in ineligible donations from 2001 to 2009. Among the serum positive-donors, there was a significant predominance among those aged 30 years or above and non-single individuals. CONCLUSIONS: The results show a rate of occurrence that is lower than that described in literature, as well as a progressive drop during the 15 years under assessment. Such results are a consequence of systematic combat of the vector since the 70s and the progressive and consistent increase of returning donors, resulting in a drop of the contamination risk factor by means of blood transfusion and in the improvement of the quality of hemotherapy practices in the HRU.

  12. Briefing Paper regarding the Establishment of a Regional Technical and Industrial Skills Training Center.

    Science.gov (United States)

    Powell, Roger Baden

    In spring 1997, Oregon's Regional Workforce Committee commissioned a study to investigate the feasibility of creating a technical and industrial skills training center in Region 12 of the state. Interviews were conducted with 40 individuals from area companies, social service agencies, and training organizations regarding the need for such a…

  13. Establishment of a Separate Psychology Service at Walter Reed Army Medical Center

    Science.gov (United States)

    1989-07-01

    Sheila Forsythe, Barbara J. Morgan); the Department of Psychology at the National Naval Medical Center, Bethesda, Maryland (CAPT Frank Mullins and...Services w2 1l have to be configured to specific staffs, available resources, and missions. To enhance leadership opportunities and carper rr𔄁-0ssion fe

  14. Maximum surgical blood ordering schedule in a tertiary trauma center in northern India: A proposal

    Directory of Open Access Journals (Sweden)

    Arulselvi Subramanian

    2012-01-01

    Full Text Available Context: Over ordering of blood is a common practice in elective surgical practice. Considerable time and effort is spent on cross-matching for each patient undergoing a surgical procedure. Aims: The aim of this study was to compile and review the blood utilization for two key departments (Neurosurgery and Surgery in a level 1 trauma center. A secondary objective was to formulate a rational blood ordering practice for elective procedures for these departments. Materials and Methods: Analysis of prospectively compiled blood bank records of the patients undergoing elective surgical, neurosurgical procedures was carried out between April 2007 and March 2009. Indices such as the cross-matched/transfused ratio (C/T ratio, transfusion index and transfusion probability were calculated. The number of red cell units required for each procedure was calculated using the equation proposed by Nuttall et al, using preoperative hemoglobin and postoperative hemoglobin for each elective surgical procedure. Results: There were 252 surgery patients (age range: 2-80 years in the study. One thousand and eighty-eight units of blood were cross-matched, 432 were transfused (CT ratio 2.5. 44.0% patients did not require transfusion during entire hospital stay. Three (50% elective procedures had CT ratio >2.5and 4 (66.6% elective procedures had TI 2.5, with five of them exceeding 4. In procedures like spinal instrumentation the CT ratio was <2.5 and 10 (90.9% of elective procedures had TI <0.5. Conclusions: In this study 40% and 22% of cross-matched blood was being utilized for elective general surgery and neurosurgical procedures, respectively. The calculated required blood units for all elective Trauma surgery procedures were more than 2 units. The calculated required blood units were less than 0.5 units in four of the 11 neurosurgical procedures, and hence only one unit should be arranged for them. It is crucial for every institutional blood bank to formulate a blood

  15. Establishing an Integrative Medicine Program Within an Academic Health Center: Essential Considerations.

    Science.gov (United States)

    Eisenberg, David M; Kaptchuk, Ted J; Post, Diana E; Hrbek, Andrea L; O'Connor, Bonnie B; Osypiuk, Kamila; Wayne, Peter M; Buring, Julie E; Levy, Donald B

    2016-09-01

    Integrative medicine (IM) refers to the combination of conventional and "complementary" medical services (e.g., chiropractic, acupuncture, massage, mindfulness training). More than half of all medical schools in the United States and Canada have programs in IM, and more than 30 academic health centers currently deliver multidisciplinary IM care. What remains unclear, however, is the ideal delivery model (or models) whereby individuals can responsibly access IM care safely, effectively, and reproducibly in a coordinated and cost-effective way.Current models of IM across existing clinical centers vary tremendously in their organizational settings, principal clinical focus, and services provided; practitioner team composition and training; incorporation of research activities and educational programs; and administrative organization (e.g., reporting structure, use of medical records, scope of clinical practice) and financial strategies (i.e., specific business plans and models for sustainability).In this article, the authors address these important strategic issues by sharing lessons learned from the design and implementation of an IM facility within an academic teaching hospital, the Brigham and Women's Hospital at Harvard Medical School; and review alternative options based on information about IM centers across the United States.The authors conclude that there is currently no consensus as to how integrative care models should be optimally organized, implemented, replicated, assessed, and funded. The time may be right for prospective research in "best practices" across emerging models of IM care nationally in an effort to standardize, refine, and replicate them in preparation for rigorous cost-effectiveness evaluations.

  16. Whole blood donor deferral analysis at a center in Western India

    Directory of Open Access Journals (Sweden)

    Agnihotri Naveen

    2010-01-01

    Full Text Available Introduction: Deferrals lead to loss of precious whole blood donors (WBD and blood units available for transfusion purposes. Knowledge of rate and causes of donor deferral can guide the recruitment strategy for WBD. Aim: To find the incidence and causes of deferral in Indian WBD and apply relevant findings to modify recruitment strategy for blood donors. Materials and Methods: Data for WBD presenting for donation in a blood center and outdoor camps over one and half year were analyzed retrospectively. National guidelines were used for selection and deferral of WBD. Result: 736 (11.6% WBD were deferred out of 6357 presenting for donation during the study period. Most (69.8% of the donors were deferred on physical examination and hemoglobin (Hb testing. Most common reasons for deferral were low Hb (55.8%, abnormal blood pressure (11.1%, medication (6.9% and underweight donors (2.9%. Significantly more volunteers were deferred than relative donors (13.97% vs 5.80%; P<0.000. Females were found to have higher deferral rate than males (53.5% vs 6.9%; P=0.000 and higher odds ratio for deferral (15.4. Donors older than 40 years of age had significantly higher chance of being deferred (P<0.05. Discussion and Conclusion: It is important to determine the rate and causes of WBD deferral to guide the recruitment and retention efforts at local, regional, and national level.

  17. Creating a Sustainable Model for Establishing Youth Gardens in Schools and Childcare Centers

    Science.gov (United States)

    Wright, William; Friese, Bettina; Carrel, Aaron; Meinen, Amy

    2013-01-01

    Purpose/Objectives: The goal of the program was to establish youth gardens across Wisconsin by conducting workshops for school staff and childcare providers on how to start and sustain a youth garden with limited resources. Methods: Evaluation utilized an end-of-workshop questionnaire and follow-up survey. The end-of-workshop questionnaire focused…

  18. Establishing a public umbilical cord blood stem cell bank for South Africa: an enquiry into public acceptability.

    Science.gov (United States)

    Meissner-Roloff, Madelein; Pepper, Michael S

    2013-12-01

    South Africa (SA) faces a large unmet need for bone marrow (BM) transplantation, which could be alleviated in part by establishing a public umbilical cord blood stem cell bank (UCB SCB). Umbilical cord blood is an increasingly utilised source of hematopoietic stem cells for BM transplantation in addition to BM or mobilized peripheral blood stem cells. Establishing a public UCB SCB would therefore be a positive step towards improving the quality of health care in SA by providing for an important unmet need. This study takes the form of an enquiry into the acceptability of establishing a public bank through an interview with and questionnaire completed by mothers-to-be in the antenatal clinic of a large public hospital in SA. Initial results are positive, with 85 % of the participants in favour of establishing a public UCB SCB in SA. This initial probe will serve as a model for a more comprehensive national enquiry into public support and acceptability in different clinics, hospitals and provinces in SA.

  19. Establishing a cell biology platform: isolation and preservation of human blood products

    OpenAIRE

    2014-01-01

    Dissertação para obtenção do Grau de Mestre em Genética Molecular e Biomedicina The use of human primary cells provide researchers in different areas with irrefutable more biologically relevant data than using cell lines or animal blood cells. The work was performed in the scope of the Cell Biology Services @ CEDOC, aiming to provide viable and trustful human primary cells and products. We had three main objectives: protocol optimizations for blood cell isolation, culture and cryopre...

  20. 75 FR 54343 - Center for Biologics Evaluation and Research eSubmitter Pilot Evaluation Program for Blood...

    Science.gov (United States)

    2010-09-07

    ...The Food and Drug Administration (FDA), Center for Biologics Evaluation and Research (CBER) is announcing an invitation to participate in a pilot evaluation program for CBER's eSubmitter Program (eSubmitter). CBER's eSubmitter has been customized as an automated biologics license application (BLA) and BLA supplement (BLS) submission system for blood and blood components. Participation in the......

  1. White paper: A plan for cooperation between NASA and DARPA to establish a center for advanced architectures

    Science.gov (United States)

    Denning, P. J.; Adams, G. B., III; Brown, R. L.; Kanerva, P.; Leiner, B. M.; Raugh, M. R.

    1986-01-01

    Large, complex computer systems require many years of development. It is recognized that large scale systems are unlikely to be delivered in useful condition unless users are intimately involved throughout the design process. A mechanism is described that will involve users in the design of advanced computing systems and will accelerate the insertion of new systems into scientific research. This mechanism is embodied in a facility called the Center for Advanced Architectures (CAA). CAA would be a division of RIACS (Research Institute for Advanced Computer Science) and would receive its technical direction from a Scientific Advisory Board established by RIACS. The CAA described here is a possible implementation of a center envisaged in a proposed cooperation between NASA and DARPA.

  2. Apical meristem organization and lack of establishment of the quiescent center in Cactaceae roots with determinate growth.

    Science.gov (United States)

    Rodríguez-Rodríguez, José Fernando; Shishkova, Svetlana; Napsucialy-Mendivil, Selene; Dubrovsky, Joseph G

    2003-10-01

    Some species of Cactaceae from the Sonoran Desert are characterized by a determinate growth pattern of the primary root, which is important for rapid lateral-root formation and seedling establishment. An analysis of the determinate root growth can be helpful for understanding the mechanism of meristem maintenance in plants in general. Stenocereus gummosus (Engelm.) Gibson & Horak and Pachycereus pringlei (S. Watson) Britton & Rose are characterized by an open type of root apical meristem. Immunohistochemical analysis of 5-bromo-2'-deoxyuridine incorporation into S. gummosus showed that the percentage of cells passing through the S-phase in a 24-h period is the same within the zone where a population of relatively slowly proliferating cells could be established and above this zone in the meristem. This indicated the absence of the quiescent center (QC) in S. gummosus. During the second and the third days of growth, in the distal meristem portion of P. pringlei roots, a compact group of cells that had a cell cycle longer than in the proximal meristem was found, indicating the presence of the QC. However, later in development, the QC could not be detected in this species. These data suggest that during post-germination the absence of the establishment of the QC within the apical meristem and limited proliferative activity of initial cells are the main components of a determinate developmental program and that establishment of the QC is required for maintenance of the meristem and indeterminate root growth in plants.

  3. Progression of Blood Pressure and Cardiovascular Outcomes in Hypertensive Patients in a Reference Center

    Energy Technology Data Exchange (ETDEWEB)

    Guimarães Filho, Gilberto Campos, E-mail: camposguimaraes@yahoo.com.br; Sousa, Ana Luiza Lima; Jardim, Thiago de Souza Veiga; Souza, Weimar Sebba Barroso; Jardim, Paulo César Brandão Veiga [Liga de Hipertensão da Faculdade de Medicina da Universidade Federal de Goiânia, Goiás, GO (Brazil)

    2015-04-15

    Hypertension is a public health problem, considering its high prevalence, low control rate and cardiovascular complications. Evaluate the control of blood pressure (BP) and cardiovascular outcomes in patients enrolled at the Reference Center for Hypertension and Diabetes, located in a medium-sized city in the Midwest Region of Brazil. Population-based study comparing patients enrolled in the service at the time of their admission and after an average follow-up of five years. Participants were aged ≥18 years and were regularly monitored at the Center up to 6 months before data collection. We assessed demographic variables, BP, body mass index, risk factors, and cardiovascular outcomes. We studied 1,298 individuals, predominantly women (60.9%), and with mean age of 56.7±13.1 years. Over time, there was a significant increase in physical inactivity, alcohol consumption, diabetes, dyslipidemia, and excessive weight. As for cardiovascular outcomes, we observed an increase in stroke and myocardial revascularization, and a lower frequency of chronic renal failure. During follow-up, there was significant improvement in the rate of BP control (from 29.6% to 39.6%; p = 0.001) and 72 deaths, 91.7% of which were due to cardiovascular diseases. Despite considerable improvements in the rate of BP control during follow-up, risk factors worsened and cardiovascular outcomes increased.

  4. Blood blister-like aneurysms: Single center experience and systematic literature review

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, Ana Marcos; Narata, Ana Paula; Yilmaz, Hasan [Interventional Neuroradiology Unit, Service of Neuroradiology, University Hospital of Geneva (Switzerland); Bijlenga, Philippe; Radovanovic, Ivan; Schaller, Karl [Service of Neurosurgery, University Hospital of Geneva (Switzerland); Lovblad, Karl-Olof [Interventional Neuroradiology Unit, Service of Neuroradiology, University Hospital of Geneva (Switzerland); Pereira, Vitor Mendes, E-mail: vitormpbr@hotmail.com [Interventional Neuroradiology Unit, Service of Neuroradiology, University Hospital of Geneva (Switzerland)

    2014-01-15

    Blood blister-like aneurysms (BBAs) are a controversial entity. They arise from non-branching sites on the supraclinoid internal carotid artery (ICA) and are suspected to originate from a dissection. Our aim is to describe the BBA cases seen in our center and to present a systematic review of the literature on BBAs. We analyzed the eleven cases of BBA admitted to our center from 2003 to 2012. We assessed the medical history, treatment modality (endovascular and/or surgery), complications and clinical outcome. The cohort included 8 women and 4 men with a mean age of 53.16 years. Treatment of the BBA consisted of stenting and coiling in 5 patients, stenting only in 4 patients, coiling and clipping in 1 patient, clipping only in 1 patient, and conservative treatment in 1 patient. A good outcome was found in 10 patients, as defined by a modified Rankin Scale (mRS) less than or equal to two at three months. A systematic review of the literature was performed, and 314 reported patients were found: 221 patients were treated with a primarily surgical approach, and 87 patients were treated with a primarily endovascular approach. A rescue or second treatment was required in 46 patients (21%). The overall estimated treatment morbidity rate was 17%, and the mortality rate was 15%. BBAs exhibit more aggressive behavior compared to saccular aneurysms, and more intra-operative complications occur with BBAs, independent of the treatment type offered. They are also significantly more likely to relapse and rebleed after treatment. Endovascular treatment offers a lower morbidity–mortality compared with surgical approaches. Multilayer flow-diverting stents appear to be a promising strategy.

  5. Blood blister-like aneurysms: single center experience and systematic literature review.

    Science.gov (United States)

    Gonzalez, Ana Marcos; Narata, Ana Paula; Yilmaz, Hasan; Bijlenga, Philippe; Radovanovic, Ivan; Schaller, Karl; Lovblad, Karl-Olof; Pereira, Vitor Mendes

    2014-01-01

    Blood blister-like aneurysms (BBAs) are a controversial entity. They arise from non-branching sites on the supraclinoid internal carotid artery (ICA) and are suspected to originate from a dissection. Our aim is to describe the BBA cases seen in our center and to present a systematic review of the literature on BBAs. We analyzed the eleven cases of BBA admitted to our center from 2003 to 2012. We assessed the medical history, treatment modality (endovascular and/or surgery), complications and clinical outcome. The cohort included 8 women and 4 men with a mean age of 53.16 years. Treatment of the BBA consisted of stenting and coiling in 5 patients, stenting only in 4 patients, coiling and clipping in 1 patient, clipping only in 1 patient, and conservative treatment in 1 patient. A good outcome was found in 10 patients, as defined by a modified Rankin Scale (mRS) less than or equal to two at three months. A systematic review of the literature was performed, and 314 reported patients were found: 221 patients were treated with a primarily surgical approach, and 87 patients were treated with a primarily endovascular approach. A rescue or second treatment was required in 46 patients (21%). The overall estimated treatment morbidity rate was 17%, and the mortality rate was 15%. BBAs exhibit more aggressive behavior compared to saccular aneurysms, and more intra-operative complications occur with BBAs, independent of the treatment type offered. They are also significantly more likely to relapse and rebleed after treatment. Endovascular treatment offers a lower morbidity-mortality compared with surgical approaches. Multilayer flow-diverting stents appear to be a promising strategy.

  6. Commission Review of a Proposal by the Santa Clarita Community College District To Establish the Canyon Country Educational Center. Commission Report 04-19

    Science.gov (United States)

    California Postsecondary Education Commission, 2004

    2004-01-01

    In this report, the Commission considers a proposal by the Santa Clara Community College District to establish an educational center in the community of Canyon Country. The district was created in 1968 when the communities of Valencia, Newhall, Canyon Country, Agua Dulce, and Val Verde voted overwhelmingly for its establishment. It serves a…

  7. Center for fetal monkey gene transfer for heart, lung, and blood diseases: an NHLBI resource for the gene therapy community.

    Science.gov (United States)

    Tarantal, Alice F; Skarlatos, Sonia I

    2012-11-01

    The goals of the National Heart, Lung, and Blood Institute (NHLBI) Center for Fetal Monkey Gene Transfer for Heart, Lung, and Blood Diseases are to conduct gene transfer studies in monkeys to evaluate safety and efficiency; and to provide NHLBI-supported investigators with expertise, resources, and services to actively pursue gene transfer approaches in monkeys in their research programs. NHLBI-supported projects span investigators throughout the United States and have addressed novel approaches to gene delivery; "proof-of-principle"; assessed whether findings in small-animal models could be demonstrated in a primate species; or were conducted to enable new grant or IND submissions. The Center for Fetal Monkey Gene Transfer for Heart, Lung, and Blood Diseases successfully aids the gene therapy community in addressing regulatory barriers, and serves as an effective vehicle for advancing the field.

  8. Genetically modified T cells targeting neovasculature efficiently destroy tumor blood vessels, shrink established solid tumors and increase nanoparticle delivery.

    Science.gov (United States)

    Fu, Xinping; Rivera, Armando; Tao, Lihua; Zhang, Xiaoliu

    2013-11-15

    Converting T cells into tumor cell killers by grafting them with a chimeric antigen receptor (CAR) has shown promise as a cancer immunotherapeutic. However, the inability of these cells to actively migrate and extravasate into tumor parenchyma has limited their effectiveness in vivo. Here we report the construction of a CAR containing an echistatin as its targeting moiety (eCAR). As echistatin has high binding affinity to αvβ3 integrin that is highly expressed on the surface of endothelial cells of tumor neovasculature, T cells engrafted with eCAR (T-eCAR) can efficiently lyse human umbilical vein endothelial cells and tumor cells that express αvβ3 integrin when tested in vitro. Systemic administration of T-eCAR led to extensive bleeding in tumor tissues with no evidence of damage to blood vessels in normal tissues. Destruction of tumor blood vessels by T-eCAR significantly inhibited the growth of established bulky tumors. Moreover, when T-eCAR was codelivered with nanoparticles in a strategically designed temporal order, it dramatically increased nanoparticle deposition in tumor tissues, pointing to the possibility that it may be used together with nanocarriers to increase their capability to selectively deliver antineoplastic drugs to tumor tissues.

  9. Cord Blood

    Directory of Open Access Journals (Sweden)

    Saeed Abroun

    2014-05-01

    Full Text Available   Stem cells are naïve or master cells. This means they can transform into special 200 cell types as needed by body, and each of these cells has just one function. Stem cells are found in many parts of the human body, although some sources have richer concentrations than others. Some excellent sources of stem cells, such as bone marrow, peripheral blood, cord blood, other tissue stem cells and human embryos, which last one are controversial and their use can be illegal in some countries. Cord blood is a sample of blood taken from a newborn baby's umbilical cord. It is a rich source of stem cells, umbilical cord blood and tissue are collected from material that normally has no use following a child’s birth. Umbilical cord blood and tissue cells are rich sources of stem cells, which have been used in the treatment of over 80 diseases including leukemia, lymphoma and anemia as bone marrow stem cell potency.  The most common disease category has been leukemia. The next largest group is inherited diseases. Patients with lymphoma, myelodysplasia and severe aplastic anemia have also been successfully transplanted with cord blood. Cord blood is obtained by syringing out the placenta through the umbilical cord at the time of childbirth, after the cord has been detached from the newborn. Collecting stem cells from umbilical blood and tissue is ethical, pain-free, safe and simple. When they are needed to treat your child later in life, there will be no rejection or incompatibility issues, as the procedure will be using their own cells. In contrast, stem cells from donors do have these potential problems. By consider about cord blood potency, cord blood banks (familial or public were established. In IRAN, four cord blood banks has activity, Shariati BMT center cord blood bank, Royan familial cord blood banks, Royan public cord blood banks and Iranian Blood Transfusion Organ cord blood banks. Despite 50,000 sample which storage in these banks, but the

  10. Clinical and functional evaluation of the joint status of hemophiliac adults at a Brazilian blood center

    Directory of Open Access Journals (Sweden)

    Adriana Aparecida Ferreira

    2013-01-01

    Full Text Available BACKGROUND: Hemophilia is a potentially disabling condition as hemophilic arthropathy develops early in life and is progressive, especially in patients treated in an on-demand regime. Objective: This study aimed to describe the structural joint status and the functional independence score of hemophiliac adults and correlate structural damage with the functional deficits found in these patients. METHODS: Hemophiliacs at the Juiz de Fora Regional Blood Center - HEMOMINAS Foundation, aged 18 years and over and treated in an on-demand regime, were clinically evaluated in respect to structural joint damage using the World Federation of Hemophilia Physical Examination Scale (WFH-PE and functional deficits using the Functional Independence Score in Hemophilia (FISH. The Spearman rank test was used to evaluate the correlation between the two scores. RESULTS: Thirty-nine patients were evaluated. The mean age was 36.8 years. Target joints were detected in 69.2% of patients studied. The mean Physical Examination Scale and Functional Independence Score were 16.87 and 25.64, respectively. Patients with mild hemophilia showed no significant joint involvement. Patients with severe or moderate hemophilia had similar results regarding structural damage (p-value < 0.001 and functional deficits (p-value = 0.001. There was statistical significance in the correlation between the two scores (r = -0.850; p-value = 0.01. CONCLUSIONS: The World Federation of Hemophilia Physical Examination Scale and Functional Independence Score in Hemophilia may be useful to clinically assess structural joint damage and functional deficits in hemophiliacs as the tools are inexpensive and easy to administer and may be able to detect hemophilic arthropathy, which results from recurrent hemarthrosis and is common in the population studied.

  11. Donor recruitment and blood collection costs for Red Cross Centers. An investigation of the economies of scale hypothesis.

    Science.gov (United States)

    Jacobs, P; Rawson, W S

    1978-01-01

    This paper presents a statistical analysis of the hypothesis that there are economies of scale in the collection of blood. Based on a national sample of Red Cross collection centers, an analysis was conducted to determine the relationship between total costs of obtaining blood as well as its recruitment and collection components, and explanatory factors such as local costs, mobile units used, and scale of operations. Adjusting for other factors, our results indicate slight diseconomies of scale at all levels of operation: that is, as scale of operations increase, collection costs rise. Only the costs associated with the recruitment and collection functions are examined in this study.

  12. The manifestation of optical centers in UV-Vis absorption and luminescence spectra of white blood human cells

    Science.gov (United States)

    Terent'yeva, Yu G.; Yashchuk, V. M.; Zaika, L. A.; Snitserova, O. M.; Losytsky, M. Yu

    2016-12-01

    A white blood human cells spectral investigation is presented. The aim of this series of experiments was to obtain and analyze the absorption and luminescence (fluorescence and phosphorescence) spectra at room temperature and at 78 K of newly isolated white blood human cells and their organelles. As a result the optical centers and possible biochemical components that form the studied spectra where identified. Also the differences between the spectra of abnormal cells (B-cell chronic lymphocytic leukemia BCLL) and normal ones were studied for the whole cells and individual organelles.

  13. [Prescribing and performing autologous blood transfusion: experience at a University Medical Center].

    Science.gov (United States)

    Bregeon, Y F; Grouille, D; Roussanne, A; Lathelize, M; Feiss, P

    1995-01-01

    Prescription and carrying out of autologous blood transfusion in a university hospital during a whole year (1992) were investigated. 554 patients were involved. 88% of them gave at least one blood unit. Three surgical groups are specified: cardiac surgery with bypass (95 patients), orthopaedic procedures with knee or hip replacement or spine surgery (276 patients) and other types of surgery (117 patients). Prescriptions of blood donation before cardiac surgery were not carried out (by the transfusion centre) twice more often than in the other groups. This is why autologous blood taking is now effected in the anaesthetic unit. 88.9% (n = 434) of all patients did not receive homologous blood (90% in the orthopaedic group, 84% in the cardiac group). 25% of the collected units were not transfused. This figure is only 8% for the cardiac patients. An efficiency index is suggested taking in account the transfusion of autologous blood units and the need of homologous transfusion: % autologous used units x % procedures realized without homologous blood. The good rate to achieve could be 70%. In aorto-coronary bypass surgery when no autologous blood was collected preoperatively, 57.5% patients received homologous blood vs 16% when at least one unit was predeposited. A short review of literature shows an increasing place of predeposited autotransfusion, with some limits in orthopaedic surgery where a combination of autologous blood donation and other erythrocytes saving methods appears to give the best results. Erythropoietin, critical haemoglobine concentration threshold, autologous transfusion in cancer patients still need further studies.

  14. Pilot social feasibility study for the establishment of a public human umbilical cord blood stem cell bank in South Africa.

    Science.gov (United States)

    Meissner-Roloff, Madelein; Young, Wendy; Rangaka, Isabella; Lombaard, Hennie; Dhai, Ames; Tsotsi, Norma; Pepper, Michael S

    2012-12-01

    There is a large unmet need in South Africa for bone marrow transplantation. Umbilical cord blood (UCB) is an important source of stem cells for the treatment of haematological and non-haematological diseases. Access to the two existing private umbilical cord blood stem cell banks (UCB SCBs) in South Africa is limited to individuals that can afford it, which further aggravates the ever increasing divide between families from different socio-economic classes. The problem is compounded by a severe global shortage of genetically compatible samples, representative of the South African demographics. Establishing a public human UCB SCB in South Africa would provide more South Africans with access to previously unavailable treatment in the form of affordable, genetically compatible stem cells for bone marrow transplantation. A public UCB SCB has many facets to consider, one of which is public preparedness and support for the bank. This was assessed in a social feasibility pilot study which is reported here. In addition to the findings of this social feasibility study, other important considerations for establishing a public human UCB SCB in SA include; (a) testing the samples for HIV and other infectious diseases (required for compliance with international regulatory standards); (b) flow cytometric analysis for enumeration of CD34+ UCB stem cells; (c) mapping of HLA genotypes/alleles; and (d) a study of the economic feasibility of this endeavour.The social feasibility study was conducted to gauge public preparedness and support for a public SCB through patient interviews and questionnaires. The process was dynamic due to its novel nature for interviewers and interviewees alike. Many obstacles were met and dealt with which lead to the compilation of results discussed here in the form of a pilot social feasibility study.In the South African context, we are faced with unique and rich challenges relating to cultural and religious differences that are further augmented by

  15. Progression of Blood Pressure and Cardiovascular Outcomes in Hypertensive Patients in a Reference Center.

    Science.gov (United States)

    Guimarães Filho, Gilberto Campos; Sousa, Ana Luiza Lima; Jardim, Thiago de Souza Veiga; Souza, Weimar Sebba Barroso; Jardim, Paulo César Brandão Veiga

    2015-02-03

    Background: Hypertension is a public health problem, considering its high prevalence, low control rate and cardiovascular complications. Objective: Evaluate the control of blood pressure (BP) and cardiovascular outcomes in patients enrolled at the Reference Center for Hypertension and Diabetes, located in a medium-sized city in the Midwest Region of Brazil. Methods: Population-based study comparing patients enrolled in the service at the time of their admission and after an average follow-up of five years. Participants were aged ≥18 years and were regularly monitored at the Center up to 6 months before data collection. We assessed demographic variables, BP, body mass index, risk factors, and cardiovascular outcomes. Results: We studied 1,298 individuals, predominantly women (60.9%), and with mean age of 56.7±13.1 years. Over time, there was a significant increase in physical inactivity, alcohol consumption, diabetes, dyslipidemia, and excessive weight. As for cardiovascular outcomes, we observed an increase in stroke and myocardial revascularization, and a lower frequency of chronic renal failure. During follow-up, there was significant improvement in the rate of BP control (from 29.6% to 39.6%; p = 0.001) and 72 deaths, 91.7% of which were due to cardiovascular diseases. Conclusion: Despite considerable improvements in the rate of BP control during follow-up, risk factors worsened and cardiovascular outcomes increased.Fundamento: A hipertensão arterial é um problema de saúde pública devido à sua elevada prevalência, baixa taxa de controle e complicações cardiovasculares. Objetivo: Avaliar o controle da pressão arterial (PA) e desfechos cardiovasculares em pacientes atendidos no Centro de Referência em Hipertensão e Diabetes, localizado em uma cidade de médio porte da Região Centro-Oeste do Brasil. Métodos: Estudo de base populacional, que comparou pacientes matriculados no serviço no momento de sua admissão e após seguimento por período m

  16. NETL to establish Dynamic Simulation Research and Training Center to promote IGCC technology with CO2 cpture

    Energy Technology Data Exchange (ETDEWEB)

    Provost, G.; Zitney, S.; Turton, R.; Erbes, M.; Stone, H.; Bhattacharyya, D.; Liese, E.; McClintock, M.; Quintrell, M.

    2009-01-01

    To meet increasing demand for education and experience with commercial-scale, coal-fired, integrated gasification combined cycle (IGCC) plants with CO2 capture, the Department of Energy’s (DOE) National Energy Technology Laboratory (NETL) is leading a project to deploy a generic, full-scope, real-time IGCC dynamic plant simulator for use in establishing a world-class research and training center, and to promote and demonstrate IGCC technology to power industry personnel. The simulator, being built by Invensys Process Systems (IPS), will be installed at two separate sites, at NETL and West Virginia University (WVU), and will combine a process/gasification simulator with a power/combined-cycle simulator together in a single dynamic simulation framework for use in engineering research studies and training applications. The simulator, scheduled to be launched in mid-year 2010, will have the following capabilities: High-fidelity, dynamic model of process-side (gasification and gas cleaning with CO2 capture) and power-block-side (combined cycle) for a generic IGCC plant fueled by coal and/or petroleum coke. Highly flexible configuration that allows concurrent training on separate gasification and combined cycle simulators, or up to two IGCC simulators. Ability to enhance and modify the plant model to facilitate studies of changes in plant configuration, equipment, and control strategies to support future R&D efforts. Training capabilities including startup, shutdown, load following and shedding, response to fuel and ambient condition variations, control strategy analysis (turbine vs. gasifier lead, etc.), representative malfunctions/trips, alarms, scenarios, trending, snapshots, data historian, etc. To support this effort, process descriptions and control strategies were developed for key sections of the plant as part of the detailed functional specification, which is serving as the basis of the simulator development. In this paper, we highlight the contents of the

  17. Relationship of daytime blood pressure and severity of obstructive sleep apnea among Chinese: a multi-center investigation in China

    Institute of Scientific and Technical Information of China (English)

    HE Quan-ying; WANG Bei; LIN Qi-chang; ZHANG Jing-nong; LIU Hui-guo; LUO Yuan-ming; LIU Jian-hong; WANG Shi; XIAO Gao-hui; LU Gan; ZHANG Jin; FENG Jing; FENG Xue-wei; CHEN Bao-yuan; ZHANG Xi-long; LIANG Zong-an; HUANG Shao-guang; KANG Jian; WANG Guang-fa; ZHANG Li-qiang; MA Li-jun

    2010-01-01

    Background Epidemiologic studies have shown an independent and definite association between obstructive sleep apnea (OSA) and hypertension. This study aimed to define the association between daytime blood pressure and severity of OSA in Chinese population in mainland of China. Methods Twenty university hospital sleep centers in mainland of China were invited by the Chinese Medical Association (CMA) to participate in this epidemiologic study and 2297 consecutive patients (aged 18-85 years; 1981 males and 316 females) referred to these twenty sleep centers for evaluation of OSA between January 2004 and April 2006 were prospectively enrolled. Nocturnal polysomnography was performed in each patient, and disease severity was assessed based on the apnea-hypopnea index (AHI). These patients were classfied into four groups: non-apneic control (control, n=257) with AHI ≤5 episodes/hour; mild sleep apnea (mild, n=402) with AHI >5 and ≤15 episodes/hour; moderate sleep apnea (moderate, n=460) with AHI >15 and ≤30 episodes/hour and severe sleep apnea (severe, n=1178) with AHI >30 episodes/hour. Daytime blood pressure measurements were performed under standardized conditions in each patient at 10 a.m. in office on the day of referring to sleep centers for getting average value. All the patients were requested to quit medications related to blood pressure for three days before the day of assessing.Results Both daytime systolic blood pressure and diastolic blood pressure values were significantly related to AHI positively (r = 0.201 and 0.276, respectively; both P values <0.001) and to nadir nocturnal oxygen saturation negatively (r= -0.215 and -0.277, respectively; both Pvalues <0.001), which were the parameters of OSA severity. In two special designed mean plots, means of daytime systolic and diastolic blood pressure increased gradually with increasing AHI. Beyond AHI of 61-65, this increasing trend reached a plateau.Conclusions The results showed that OSA severity was

  18. Custodiol versus blood cardioplegia in pediatric cardiac surgery, two-center study

    Directory of Open Access Journals (Sweden)

    Ebtehal A. Qulisy

    2016-05-01

    Conclusions: Custodial cardioplegia is associated with less optimal myocardial protection and higher adverse outcomes compared to cold blood cardioplegia in children undergoing cardiac surgery. A randomized comparison is warranted.

  19. Efficacy and Safety of Frozen Blood for Transfusion in Trauma Patients - A Multi-Center Trial

    Science.gov (United States)

    2015-04-01

    shown to be a major risk factor for post-injury multiple organ failure [24,26,27,29,46,47]. Koch et al. found associations between age of blood...of stay, acute respiratory distress syndrome, acute renal failure, transfusion reaction, deep venous thrombosis , and mortality) were recorded. Acute...Blackwell J, Ciesla DJ, et al. Age of transfused blood is an independent risk factor for postinjury multiple organ failure. Am J Surg. 1999; 178(6):570

  20. Response to post-donation counseling is still a challenge in outdoor voluntary blood donation camps: A survey from a tertiary care regional blood center in Eastern India

    Directory of Open Access Journals (Sweden)

    Somnath Mukherjee

    2014-01-01

    Full Text Available Background: Blood transfusion carries the risk of transmission of several infectious agents. The latest method for blood screening, nucleic acid testing is not affordable in developing countries. Aim: The study was aimed to find response to post-donation counseling for reactive markers among the voluntary blood donors donating in blood donation camps. Material and Methods: This 1 year study was conducted in 2011. Transfusion transmitted infections testing was performed by routine enzyme linked immunosorbent assay method. The initial human immunodeficiency virus (HIV reactive donors who returned back to the blood bank were confidentially counseled and referred to the Integrated Counseling Cum Testing Center (ICTC. The hepatitis B surface antigen (HBsAg and anti-hepatitis C virus (HCV reactive donors were referred to the gastroenterology department for confirmation by qualitative polymerase chain reaction (PCR, Roche Diagnostics, Germany and followed-up. Results: Twenty seven thousand two hundred forty six 27,246 units were collected during the survey. One hundred twenty nine129 units were reactive for HIV 1 and 2, 99 were reactive for HCV, 206 for hepatitis B virus (HBV. Of these reactive donors, 138 could be personally communicated. Out of 47, 27 donors who returned for counseling were initially reactive for HIV 1 and 2, 8 for HBsAg and 12 for anti-HCV. Two were positive for HBV deoxyribonucleic acid and one was positive for HCV ribonucleic acid. The HIV positivity was detected in 1 of 27 donors at ICTC. Conclusion: The response to the post-donation counseling appears in this study to be only 34% (47/138, which is still a challenge.

  1. Blood

    Science.gov (United States)

    ... Also, blood is either Rh-positive or Rh-negative. So if you have type A blood, it's either A positive or A negative. Which type you are is important if you need a blood transfusion. And your Rh factor could be important ...

  2. Interpreting and managing blood lead levels of less than 10 microg/dL in children and reducing childhood exposure to lead: recommendations of the Centers for Disease Control and Prevention Advisory Committee on Childhood Lead Poisoning Prevention.

    Science.gov (United States)

    Binns, Helen J; Campbell, Carla; Brown, Mary Jean

    2007-11-01

    Lead is a common environmental contaminant. Lead exposure is a preventable risk that exists in all areas of the United States. In children, lead is associated with impaired cognitive, motor, behavioral, and physical abilities. In 1991, the Centers for Disease Control and Prevention defined the blood lead level that should prompt public health actions as 10 microg/dL. Concurrently, the Centers for Disease Control and Prevention also recognized that a blood lead level of 10 microg/dL did not define a threshold for the harmful effects of lead. Research conducted since 1991 has strengthened the evidence that children's physical and mental development can be affected at blood lead levels of children they examine, provide families with lead-prevention counseling, and follow blood lead screening recommendations established for their areas. As circumstances permit, clinicians should consider referral to developmental programs for children at high risk for exposure to lead and more frequent rescreening of children with blood lead levels approaching 10 microg/dL. In addition, clinicians should direct parents to agencies and sources of information that will help them establish a lead-safe environment for their children. For these preventive strategies to succeed, partnerships between health care providers, families, and local public health and housing programs should be strengthened.

  3. Prevalence of human T-cell lymphotropic virus types 1 and 2 in blood donors of the Caruaru Blood Center (Hemope

    Directory of Open Access Journals (Sweden)

    Waleska Mayara Gomes de Lima

    2013-01-01

    Full Text Available BACKGROUND: There is difficulty in gathering data on the prevalence of human T-cell lymphotropic virus in blood donors as confirmatory testing is not mandatory in Brazil. This suggests there may be an underreporting of the prevalence. OBJECTIVE: To estimate the prevalence of human T-cell lymphotropic virus types 1 and 2 in donors of a blood bank in Caruaru, Brazil. METHODS: This was an observational, epidemiological, descriptive, longitudinal and retrospective study with information about the serology of donors of the Caruaru Blood Center, Fundação de Hematologia e Hemoterapia de Pernambuco (Hemope from May 2006 to December 2010. The data were analyzed using the Excel 2010 computer program (Microsoft Office(r. RESULTS: Of 61,881 donors, 60 (0.096% individuals were identified as potential carriers of human T-cell lymphotropic virus types 1 and 2. Of these, 28 (0.045% were positive and 32 (0.051% had inconclusive results in the serological screening. Forty-five (0.072% were retested; 17 were positive (0.027% and 3 inconclusive (0.005%. After confirmatory tests, 8 were positive (0.013%. Six (75% of the confirmed cases were women. CONCLUSION: Epidemiological surveys like this are very important in order to create campaigns to attract donors and reduce the costs of laboratory tests.

  4. Opportunity of objective account of the colorimetric procedure using benzidine indicative at establishing the preliminary presence of blood on the material evidences

    Directory of Open Access Journals (Sweden)

    A. V. Konovalenko

    2015-01-01

    Full Text Available The article presents a modification of the colorimetric method for the preliminary establishment of presence of blood in the stainson the material evidences using benzidine test. The proposed modification is accompanied by photometric accounting and computer processing of the results. Performance, objectivity, as well as other features and advantages of this method when used in forensic practice are described in detail.

  5. HMSRP Hawaiian Monk Seal Blood Values (Establishing hematology and serum chemistry reference ranges for wild Hawaiian Monk Seals)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Hematology and serum chemistry evaluations are essential to a patients comprehensive health exam by providing measures of organ function, blood cell volume and...

  6. Distribution of blood derivatives by registered blood establishments that qualify as health care entities; Prescription Drug Marketing Act of 1987; Prescription Drug Amendments of 1992; delay of applicability date. Final rule; delay of applicability date.

    Science.gov (United States)

    2006-11-13

    The Food and Drug Administration (FDA) is further delaying, until December 1, 2008, the applicability date of a certain requirement of a final rule published in the Federal Register of December 3, 1999 (64 FR 67720) (the final rule). The final rule implements the Prescription Drug Marketing Act of 1987 (PDMA), as modified by the Prescription Drug Amendments of 1992 (PDA), and the Food and Drug Administration Modernization Act of 1997 (the Modernization Act). The provisions of the final rule became effective on December 4, 2000, except for certain provisions whose effective or applicability dates were delayed in five subsequent Federal Register notices, until December 1, 2006. The provision with the delayed applicability date would prohibit wholesale distribution of blood derivatives by registered blood establishments that meet the definition of a "health care entity." In the Federal Register of February 1, 2006 (71 FR 5200), FDA published a proposed rule specific to the distribution of blood derivatives by registered blood establishments that qualify as health care entities (the proposed rule). The proposed rule would amend certain limited provisions of the final rule to allow certain registered blood establishments that qualify as health care entities to distribute blood derivatives. In response to the proposed rule, FDA received substantive comments. As explained in the SUPPLEMENTARY INFORMATION section of this document, further delaying the applicability of Sec. 203.3(q) (21 CFR 203.3(q)) to the wholesale distribution of blood derivatives by health care entities is necessary to give the agency additional time to address comments on the proposed rule, consider whether regulatory changes are appropriate, and, if so, to initiate such changes.

  7. Establishment of a real-time PCR for quantifying transforming growth factor beta1 in blood of hepatocellular carcinoma patients

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Background: The carcinogenesis of hepatocellular carcinoma (HCC) is a multi-factorial, multistep and complex process. Its prognosis is poor and early detection is of the utmost importance. Transforming growth factor β1 (TGF-β1) message RNA (mRNA) has been reported to be elevated in HCC patients using Northern blotting. However, little work has been done about the detection of TGF-β1 mRNA levels in peripheral blood of patients with HCC using the real-time polymerase chain reactions (PCR) method. Objective: To assess the prognostic value of quantitative levels of TGF-β1 mRNA in peripheral blood of patients with HCC, and to investigate the relationship between the expression of TGF-β1 mRNA in peripheral blood and many diagnostic and pathological factors. Methods: We developed an optimized Taqman real-time PCR to quantify TGF-β1 mRNA in peripheral blood of 53 patients with HCC and 44 healthy volunteers. In addition, blood was collected from patients with HCC for measuring levels of total bilirubin (TBil), prealbumin, albumin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma glutamyltranspeptidase (GGT), alpha-L-fucosidase (AFU), alpha fetoprotein (AFP), carcino-embryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), viral load and platelet counts. Statistical analysis was performed using the SPSS software system (SPSS 10.0). Results: In real-time PCR, fluorescence was detectable in all blood specimens from patients with HCC and healthy volunteers. The levels of TGF-β1 mRNA expression in patients with HCC were significantly higher compared to that in healthy volunteers (P<0.000 1), suggesting an association of the activated TGF-β1 gene transcription with hepatocarcinogenesis. Patients with HCC were divided into 2 groups according to their TGF-β1 mRNA above (group A, n=28) or below (group B, n=25) the mean level. Statistical results demonstrated that TGF-β1 mRNA expression level was correlated with patients age, serum levels of CEA

  8. Establishment of Customer-centered Production Management Model%以客户为中心的生产管理模式建立

    Institute of Scientific and Technical Information of China (English)

    陈永道

    2013-01-01

    以某大型机械设备制造企业在建立“以客户为中心”的生产管理模式过程中积累的经验为,对制造企业如何将“以客户为中心”的经营管理理念落到实处进行了探讨.%This paper discusses the implementation of the management idea of "customer-centered" operation in manufacturing enterprises based on the experience accumulated in the process of establishing customer-centered management model in a large-scale mechanical equipment manufacturing company.

  9. Establishing baseline levels of trace elements in blood and skin of bottlenose dolphins in Sarasota Bay, Florida: Implications for non-invasive monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Bryan, Colleen E. [National Institute of Standards and Technology, Hollings Marine Laboratory, 331 Fort Johnson Road, Charleston, South Carolina 29412 (United States); College of Charleston, Grice Marine Laboratory, 205 Fort Johnson Road, Charleston, South Carolina 29412 (United States)], E-mail: colleen.bryan@nist.gov; Christopher, Steven J. [National Institute of Standards and Technology, Hollings Marine Laboratory, 331 Fort Johnson Road, Charleston, South Carolina 29412 (United States); Balmer, Brian C.; Wells, Randall S. [Chicago Zoological Society c/o Mote Marine Laboratory, 1600 Ken Thompson Parkway, Sarasota, Florida 34236 (United States)

    2007-12-15

    Several major unusual mortality events occurring in recent years have increased the level of concern for the health of bottlenose dolphin populations along the United States Atlantic and Gulf of Mexico coasts. Trace element concentrations were examined in a population of free-ranging dolphins in Sarasota Bay, Florida, in order to develop a benchmark for future comparisons within and between populations. Whole blood (n = 51) and skin (n = 40) samples were collected through capture and release health assessment events during 2002-2004. Samples were analyzed for Al, V, Cr, Mn, Cu, Zn, As, Se, Rb, Sr, Mo, Cd, and Pb by inductively coupled plasma mass spectrometry (ICPMS) and Hg via atomic fluorescence spectrometry (AFS). Trace element concentrations (wet mass) in skin were 2 to 45 times greater than blood, except Cu was approximately 1.5 times higher in blood. Statistically strong correlations (p < 0.05) were found for V, As, Se, Rb, Sr, and Hg between blood and skin demonstrating that these tissues can be used as effective non-lethal monitoring tools. The strongest correlation was established for Hg (r = 0.9689) and concentrations in both blood and skin were above the threshold at which detrimental effects are observed in other vertebrate species. Female dolphins had significantly greater Hg concentrations in blood and skin and Pb concentrations in skin, relative to males. Calves exhibited significantly lower V, As, and Hg concentrations in blood and V and Hg concentrations in skin, relative to other age classes. Rubidium and Cu concentrations in skin were greatest in subadults and calves, respectively. In blood, V, Zn, and As concentrations were significantly greater in winter, relative to summer, and the opposite trend was observed for Rb and Sr concentrations. In skin, Cu and Zn concentrations were significantly greater in winter, relative to summer, and the opposite trend was observed for Mn, Rb, Cd, and Pb concentrations. The baseline concentrations and trends

  10. In Vitro Blood-Brain Barrier Models-An Overview of Established Models and New Microfluidic Approaches

    DEFF Research Database (Denmark)

    Wolff, Anette; Antfolk, Maria; Brodin, Birger;

    2015-01-01

    The societal need for new central nervous system (CNS) medicines is substantial, because of the global increase in life expectancy and the accompanying increase in age-related CNS diseases. Low blood-brain barrier (BBB) permeability has been one of the major causes of failure for new CNS drug...... candidates. There has therefore been a great interest in cell models, which mimic BBB permeation properties. In this review, we present an overview of the performance of monocultured, cocultured, and triple-cultured primary cells and immortalized cell lines, including key parameters such as transendothelial......-of-the-art models and it was noted that, although they show great promise, these systems have not yet reached beyond the proof-of-concept stage. In general, it was found that there were large variations in experimental protocols, BBB phenotype markers, and paracellular flux markers used. It is the author's opinion...

  11. The estimation of prevalence, incidence, and residual risk of transfusion-transmitted human hepatitis B infection from blood donated at the Anhui blood center, China, from 2009 to 2011.

    Directory of Open Access Journals (Sweden)

    Wuping Li

    Full Text Available BACKGROUND: The high prevalence of hepatitis B virus (HBV among the Chinese population poses a threat to blood safety; however, few studies have examined epidemiological data regarding HBV infection of Chinese blood donors. The present study investigated the demographic characteristics of blood donors at the Anhui blood center in China, the prevalence, incidence, and residual risk (RR associated with hepatitis B surface antigen (HBsAg expression in terms of transfusion transmitted HBV (TTHBV infections. METHODS: The demographic characteristics and HBV status of people who donated blood at the Anhui blood center between 2009 and 2011 were retrospectively analyzed. The incidence of HBV was estimated through HBsAg yield approach. The window period model was then used to estimate the RR of TTHBV infection. RESULTS: The typical donor at the Anhui blood center was a first-time volunteer, aged less than 25 years, unmarried, of Han ethnicity, and with an education below high school level. The prevalence of HBV infection among repeat donors, first-time donors, and all donors was 28.9, 127.2 and 82.1 per 100,000, respectively. The incidence estimate was 333.9 per 10(5 person-years. Using an infectious window period of 59 days, the RR for HBV was estimated to be 1 in 1853 between 2009 and 2011. CONCLUSIONS: The incidence and RR of HBV in Chinese blood donors are much higher than those of donors in developed countries. This is because sensitive ELISAs and nucleic acid tests are not available in China. Further work is needed to improve both the safety and availability of blood products in China.

  12. The Quality Control of Blood Purification Center Dialysis Water%血液净化中心透析用水的质量控制

    Institute of Scientific and Technical Information of China (English)

    顾鸣燕; 刁占帅; 杨洁泉

    2015-01-01

    目的:探讨血液净化中心进行透析用水质量控制的方法。方法:按照透析用水的相关规范要求,建立质量控制小组,制定管理计划,按要求对血液净化中心的布局、安装流程、水处理系统的日常维护和监测、水处理系统的清洗消毒、透析用水的水质监控等方面进行管理,记录相关结果,对异常结果有分析、总结和持续改进。比较实施新的管理办法前后的相关数据。结果:新的管理办法实施前后,检测出水口的细菌菌落数和类毒素含量,结果使用校正字2检验进行比较,差异具有统计学意义(P<0.05)。结论:采用新的管理办法后,透析用水的水质有明显提高。%Objective: To explore the methods of dialysis water quality control in the blood purification center. Method: According to the requirements of related standard dialysis water, the quality control unit was established, a management plan was made. Manage the layout of blood purification center, the installation process, the daily maintenance and monitoring of water treatment system, the cleaning and disinfection of water treatment system and the monitoring of dialysis water quality etc by the requirements. Record the results, analyze the abnormal results and improve. To compare related data before and after the implementation of new management measures.Result:Test the bacterial colonies and toxoid at the water outlet place before and after the implementation of new management practices, compare the results to the corrected χ² inspection, the difference was statistically significant (P<0.05).Conclusion: The quality of dialysis water is obviously improved after using the new management method.

  13. Nurses’ knowledge of blood transfusion in medical training centers of Shahrekord University of Medical Science in 2004

    OpenAIRE

    Aslani, Yosef; Etemadyfar, Shahram; Noryan, Kobra

    2010-01-01

    BACKGROUND: Using blood and blood components is a common therapeutic procedure in hospitals. Nurses have an important role in a safe blood transfusion. Therefore, it is crucial for nurses to have sufficient knowledge of situations, amount and methods of using blood components, possible side effects and necessary cares. This study investigated nurses’ knowledge of blood transfusion. METHODS: This was a cross-sectional descriptive study on 117 nurses in medical training hospitals of Shahrekord ...

  14. Stakeholders' Perceptions About a Newly Established Dental School with a Problem-Based, Student-Led, Patient-Centered Curriculum: A Qualitative Study.

    Science.gov (United States)

    Ali, Kamran; Tredwin, Christopher; Kay, Elizabeth; Slade, Anita

    2016-03-01

    The aim of this study was to explore the perceptions of stakeholders regarding a newly established dental school with a problem-based, student-led, patient-centered curriculum in a community setting. Qualitative methods using 16 semistructured interviews and two focus groups were used to engage a range of stakeholders from students to faculty members to practitioners. Purposive sampling was employed with participants contacted through professional channels. Interview and focus group transcripts were transcribed verbatim. The data were analyzed thematically using an inductive approach. Themes related to preparedness of dental graduates were identified during data analyses. Early clinical exposure with patients in the first year of the course, holistic care using a patient-centered approach, and the acquisition of communication skills, professionalism, team-working skills, reflective practice, and evidence-informed clinical practice were perceived to be key strengths of the curriculum. The participants also expressed the need to strengthen teaching of life sciences and provide additional clinical experience in simulated general dental practice clinics. This study provides insight into the perceptions of a wide range of stakeholders and provides a deeper understanding of the merits and challenges of an innovative undergraduate dental curriculum.

  15. European Group for Blood and Marrow Transplantation Centers with FACT-JACIE Accreditation Have Significantly Better Compliance with Related Donor Care Standards.

    Science.gov (United States)

    Anthias, Chloe; O'Donnell, Paul V; Kiefer, Deidre M; Yared, Jean; Norkin, Maxim; Anderlini, Paolo; Savani, Bipin N; Diaz, Miguel A; Bitan, Menachem; Halter, Joerg P; Logan, Brent R; Switzer, Galen E; Pulsipher, Michael A; Confer, Dennis L; Shaw, Bronwen E

    2016-03-01

    Previous studies have identified healthcare practices that may place undue pressure on related donors (RDs) of hematopoietic cell products and an increase in serious adverse events associated with morbidities in this population. As a result, specific requirements to safeguard RD health have been introduced to Foundation for the Accreditation of Cellular Therapy/The Joint Accreditation Committee ISCT and EBMT (FACT-JACIE) Standards, but the impact of accreditation on RD care has not previously been evaluated. A survey of transplant program directors of European Group for Blood and Marrow Transplantation member centers was conducted by the Donor Health and Safety Working Committee of the Center for International Blood and Marrow Transplant Research to test the hypothesis that RD care in FACT-JACIE accredited centers is more closely aligned with international consensus donor care recommendations than RD care delivered in centers without accreditation. Responses were received from 39% of 304 centers. Our results show that practice in accredited centers was much closer to recommended standards as compared with nonaccredited centers. Specifically, a higher percentage of accredited centers use eligibility criteria to assess RDs (93% versus 78%; P = .02), and a lower percentage have a single physician simultaneously responsible for an RD and their recipient (14% versus 35%; P = .008). In contrast, where regulatory standards do not exist, both accredited and nonaccredited centers fell short of accepted best practice. These results raise concerns that despite improvements in care, current practice can place undue pressure on donors and may increase the risk of donation-associated adverse events. We recommend measures to address these issues through enhancement of regulatory standards as well as national initiatives to standardize RD care.

  16. Blood Transfusion

    Science.gov (United States)

    ... to their work or home. The availability of plastic bags that can have one or more satellite bags ... in preparing the donated blood. The use of plastic bags allows the blood center to make a variety ...

  17. Agreement between the Government of the Republic of Chile and ESO for Establishing a New Center for Observation in Chile - ALMA

    Science.gov (United States)

    2002-10-01

    On October 21, 2002, the Minister of Foreign Affairs of the Republic of Chile, Mrs. María Soledad Alvear and the ESO Director General, Dr. Catherine Cesarsky , signed an Agreement that authorizes ESO to establish a new center for astronomical observation in Chile . This new center for astronomical observation will be for the Atacama Large Millimeter Array (ALMA) , the largest ground based astronomical project for the next decades. On this occasion, Minister Alvear stated that "we want to have ALMA working as soon as possible, which will constitute a pride not only to Chilean scientists but for the whole country and in particular, for the community of the Antofagasta Region" . ESO Director General Cesarsky said that "signing this agreement between the Government of Chile and ESO is a historical step in the astronomical collaboration between Chile and ESO and it will allow Chile to host, once again, a project of worldwide interest and impact" . ALMA is a joint project on equal basis between ESO and AUI (Associated Universities, Inc.). These organizations represent the scientific interests of Europe on one side and the United States with Canada on the other side. Chilean astronomers are closely involved with the project and 10% of the observing time will be reserved for Chilean science. ALMA will be built in the Andes, on the Plateau of Chajnantor (see the Chajnantor Photo Gallery ), 5000 metres above sea level and 60 km East of the town of San Pedro de Atacama. The array will be comprised of 64 antennas with unprecedent sensitivity and angular resolution that will allow studying the origin of galaxies, stars and planets, opening new horizons for astronomy, and being able to observe galaxies across the universe where stars are being formed. The agreement now signed between ESO and the Government of the Republic of Chile recognizes the interest that the ALMA Project has for Chile, as it will deepen and strengthen the cooperation in scientific and technological matters

  18. Establishment of the model of white blood cell membrane chromatography and screening of antagonizing TLR4 receptor component from Atractylodes macrocephala Koidz

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    A model of white blood cell membrane chromatography (WB-CMC) was established to screen active component from Atractylodes macrocephala Koidz. The component can antagonize Toll-like receptor 4 (TLR4) and inhibit inflammatory reaction. In the model of WB-CMC, cell membrane stationary phase (CMSP) was prepared by immobilizing the rabbit white blood cell membrane (WBCM) onto the surface of silica carrier and taxinol was used as a model molecule. The active component which can act on WBCM and its receptor (such as TLR4) as an effective target in A. macrocephala was determined by using a replacement experiment. The anti-inflammatory effects of the active component were tested by using pharmacological methods in vivo. The results indicated that the retention characteristics of atractylenolide I as active component was similar to that of taxinol in the model of WB-CMC. And so, atractylenolide I acted on the WBCM and TLR4 and its anti-inflammatory activity was related with antagonizing TLR4. Therefore, the interaction between the active component and WBCM and its receptor can be simulated by the model of WB-CMC in vitro. This model can be used to screen active components and to study effective characteristics for acting on definite targets.

  19. FIV establishes a latent infection in feline peripheral blood CD4+ T lymphocytes in vivo during the asymptomatic phase of infection

    Directory of Open Access Journals (Sweden)

    Murphy Brian

    2012-02-01

    Full Text Available Abstract Background Feline immunodeficiency virus (FIV is a lentivirus of cats that establishes a lifelong persistent infection with immunologic impairment. Results In an approximately 2 year-long experimental infection study, cats infected with a biological isolate of FIV clade C demonstrated undetectable plasma viral loads from 10 months post-infection onward. Viral DNA was detected in CD4+CD25+ and CD4+CD25- T cells isolated from infected cats whereas viral RNA was not detected at multiple time points during the early chronic phase of infection. Viral transcription could be reactivated in latently infected CD4+ T cells ex vivo as demonstrated by detectable FIV gag RNA and 2-long terminal repeat (LTR circle junctions. Viral LTR and gag sequences amplified from peripheral blood mononuclear cells during early and chronic stages of infection demonstrated minimal to no viral sequence variation. Conclusions Collectively, these findings are consistent with FIV latency in peripheral blood CD4+ T cells isolated from chronically infected cats. The ability to isolate latently FIV-infected CD4+ T lymphocytes from FIV-infected cats provides a platform for the study of in vivo mechanisms of lentiviral latency.

  20. Treatment of pediatric patients and young adults with particle therapy at the Heidelberg Ion Therapy Center (HIT: establishment of workflow and initial clinical data

    Directory of Open Access Journals (Sweden)

    Combs Stephanie E

    2012-10-01

    Full Text Available Abstract Background To report on establishment of workflow and clinical results of particle therapy at the Heidelberg Ion Therapy Center. Materials and methods We treated 36 pediatric patients (aged 21 or younger with particle therapy at HIT. Median age was 12 years (range 2-21 years, five patients (14% were younger than 5 years of age. Indications included pilocytic astrocytoma, parameningeal and orbital rhabdomyosarcoma, skull base and cervical chordoma, osteosarcoma and adenoid-cystic carcinoma (ACC, as well as one patient with an angiofibroma of the nasopharynx. For the treatment of small children, an anesthesia unit at HIT was established in cooperation with the Department of Anesthesiology. Results Treatment concepts depended on tumor type, staging, age of the patient, as well as availability of specific study protocols. In all patients, particle radiotherapy was well tolerated and no interruptions due to toxicity had to be undertaken. During follow-up, only mild toxicites were observed. Only one patient died of tumor progression: Carbon ion radiotherapy was performed as an individual treatment approach in a child with a skull base recurrence of the previously irradiated rhabdomyosarcoma. Besides this patient, tumor recurrence was observed in two additional patients. Conclusion Clinical protocols have been generated to evaluate the real potential of particle therapy, also with respect to carbon ions in distinct pediatric patient populations. The strong cooperation between the pediatric department and the department of radiation oncology enable an interdisciplinary treatment and stream-lined workflow and acceptance of the treatment for the patients and their parents.

  1. Establishment of wound care center and development of burns and plastic surgery discipline%伤口治疗中心建立与烧伤整形学科发展

    Institute of Scientific and Technical Information of China (English)

    刘毅

    2011-01-01

    @@ 伴随着我国社会经济的高速发展,人民生活水平日益提高,生活习惯和饮食习惯逐渐发生变化,由此也导致疾病谱出现相应改变.以糖尿病为例,我国糖尿病发病率呈逐年增高的趋势.%To study the interaction between establishment of wound care center and development of discipline of burns and plastic surgery. The changes in number of outpatient,time for dressing change per patient, outpatient service income,number of inpatients and operations in our hospital were summarized and retrospectively analyzed before and after establishment of wound care center. The proportion of patients with chronic wounds and skin and soft tissue defects after trauma among all inpatients in the same term were investigated. Meanwhile, the development of discipline of burns and plastic surgery before and after establishment of wound care center was analyzed. Compared with those in the year before establishment of wound care center, outpatient number, time for dressing change per patient,outpatient service income, inpatient number, and amount of operations were all increased(with increase rate of 330% , 569%,325%, 161% , and 173%, respectively) in the year after establishment of wound care center. The ratio of patients with chronic wounds and skin and soft tissue defects after trauma among all inpatients was respectively increased from 4.3% and 4.5% in the year before establishment of wound care center to 9.2% and 12.4% in the year after establishment of wound care center. Patient satisfaction, bed utilization rate, levels of wound treatment and repair were all improved after establishment of wound care center. So we come to conclusions as follows. Establishment of wound care center can promote development of the standard of burns and plastic surgery. Comprehensive use of multidisciplinary theories and techniques concerning burns, plastic and aesthetic surgery, medical aesthetics, etc. can be beneficial for improvement of quality of wound

  2. 2013 report from the Center for International Blood and Marrow Transplant Research (CIBMTR): current uses and outcomes of hematopoietic cell transplants for blood and bone marrow disorders.

    Science.gov (United States)

    Pasquini, Marcelo; Wang, Zhiwei; Horowitz, Mary M; Gale, Robert Peter

    2013-01-01

    Data reported herein indicate increasing use of hematopoietic cell transplants for persons with blood and bone marrow disorders. Recent trends include increasing use of alternative donors including human leukocyte antigen (HLA)-matched unrelated persons and HLA-matched umbilical cord blood cells, increasing use of blood cell rather than bone marrow grafts, and increasing use of reduced-intensity pretransplant conditioning regimens. Many of these shifts are driven by logistical considerations such as the need for donors in persons without an HLA-identical sibling or expanding use of allotransplants to older persons. Many changes in transplant practices are not supported by results of large randomized trials. More data are needed to critically-assess the impact of these changes.

  3. Reasons for discarding blood in the Guangzhou Blood Center,during 2010-2012%2010-2012年广州市无偿献血血液报废情况分析

    Institute of Scientific and Technical Information of China (English)

    徐国胜; 黄可君; 游冉冉

    2013-01-01

    目的 对近年广州市无偿献血血液报废情况进行分析,探讨降低血液报废率的措施,以减少血液浪费.方法 收集广州血液中心2010-2012年所有血液采集制备信息和血液报废的信息,使用统计软件进行整理分析.结果 共采集制备血液2 827 955 U,报废179 794 U,报废率为6.35%;感染性不合格血液导致的报废占总报废量的64.79%,是血液报废的主要原因.感染性不合格血液报废率由高到低依次为ALT (2.12%) >HBV (0.85%)>梅毒(0.53%)>HCV(0.49%)>HⅣ(0.12%);非感染性不合格原因的报废占总报废量的35.20%,报废率由高到低依次为乳糜血(1.63%)>过期血(0.27%)>血袋破裂和渗漏(0.16%)>其他(0.08%)>溶血(0.06%)>血凝块(0.01%)>纤维蛋白析出(0.005%).结论 血液报废的主要原因是感染性标志物阳性导致的血液不合格.做好献血前的征询和宣传,进行ALT初筛,加强献血知识普及和献血前注意事项的告知,对降低血液报废率,加强血液安全有重要意义.%Objective To determine the rate of discard of blood and blood component and identify its reasons at the Guangzhou Blood Center,during the period of 2010-2012,and thus to provide suggestions to reduce the rate of discard and improve the efficiency of the blood transfusion services (BTS).Methods The data on the number of discarded whole blood units and its components,reasons for discard,and the number of blood components processed as well as the number of collected blood units were obtained from the Guangzhou Blood Center Information System and analyzed.Results The total number of whole blood and blood component collected and prepared in 2010-2012 was 2 827 955 U.The total number of discarded whole blood units and its components was 179 794 U (6.35%).The main reason for discarding these blood units was the positive detection of different transfusion transmissible infections (TTIS) (64.79%),followed by

  4. Epidemiological profile of hepatitis C in blood donors at the Uberaba Regional Blood Center Perfil epidemiológico para hepatite C em doadores de sangue do Hemocentro Regional de Uberaba

    Directory of Open Access Journals (Sweden)

    Fernanda Bernadelli Garcia

    2009-02-01

    Full Text Available The aim of the present study was to outline the serological profile of hepatitis C among blood donors seen at the Uberaba Regional Blood Center, Hemominas Foundation, over the last 14 years. The frequency of hepatitis C was compared between first-time and repeat donors and the epidemiological characteristics of those with positive and indeterminate ELISA anti-HCV (third and fourth generation were analyzed based on the donor histories kept in the archives of the Uberaba Regional Blood Center. The serological ineligibility rate was 0.3%, with higher prevalence in the group of first-time donors. We did not find any significant differences regarding age, skin color, marital status or place of residence between eligible and ineligible donors; however, the frequency of positive serology was higher among men. The lower (0.3% rate of ineligibility due to hepatitis C that was observed at the Uberaba Regional Blood Center, in relation to most Brazilian blood centers, is probably due to the large number of repeat donors (83.3%. This reinforces the importance of achieving donor commitment for increasing transfusion safety.O objetivo deste estudo foi traçar o perfil sorológico para a hepatite C nos doadores de sangue do Hemocentro Regional de Uberaba/Fundação Hemominas nos últimos 14 anos, comparando a sua ocorrência em doadores iniciais e de retorno e analisando as características epidemiológicas daqueles com ELISA anti-HCV (terceira e quarta geração positivo e indeterminado, a partir dos históricos dos doadores nos arquivos do Hemocentro Regional de Uberaba. A inaptidão sorológica encontrada foi de 0,3%, com maior ocorrência no grupo de doadores iniciais. Não encontramos diferenças significativas quanto à idade, cor da pele, estado civil e local de residência entre os aptos e os inaptos, porém a ocorrência de sorologia positiva foi maior nos homens. A menor prevalência de inaptidão para hepatite C (0,3% no Hemocentro Regional de

  5. Effect of antifibrinolytic drugs on transfusion requirement and blood loss during orthotopic liver transplantation: Results from a single center

    Directory of Open Access Journals (Sweden)

    Devi A

    2008-01-01

    Full Text Available Background: During orthotopic liver transplantation (OLT, activation of the fibrinolytic system can contribute significantly to perioperative bleeding. Prophylactic administration of antifibrinolytic agents has been shown to reduce blood loss and the need for allogenic transfusion. Objective: To study the effect of antifibrinolytics on requirement of blood components, blood loss and operative time during OLT in patients with end stage liver disease, reporting to a single centre. Materials and Methods: Consecutive patients who underwent OLT at this centre during the period February 2003-October 2007 were the subjects of this study. Based on the individual anesthesiologist′s preference, patients were assigned to receive either two million units of aprotinin (AP as a bolus followed by 5,00,000 units/hour or 10 mg/kg tranexamic acid (TAas a bolus followed by 10 mg/kg every six to eight hours, administered from the induction till the end of the surgery. Transfusion policy was standardized in all patients. Intraoperative red cell salvage was done wherever possible. The effect of these two antifibrinolytic drugs on transfusion requirement was evaluated as a whole and in a sub group of patients from each treatment group and compared with a concurrent control group that did not receive antifibrinolytic drugs. Results: Fifty patients (40 M / 10 F, 44 adults, 6 pediatric patients underwent OLT in the study period. Fourteen patients were given AP, 25 patients were given TA and 11 patients did not receive any of the agents(control group. The median volume of total blood components transfused in antifibrinolytic group (n=39 was 4540 ml(0-19,200ml, blood loss 5 l(0.7-35l and operative time 9h (4.5-17h and that of control group(n=11 was 5700 ml(0-15,500ml, 10 l(0.6-25 l and 9h (6.4-15.8h respectively. The median volume of blood transfusions, blood loss and operative time was lesser in AP group(n=14 than that of TA group(n=25. Conclusion: There is definite

  6. Transplant Center Search Form

    Science.gov (United States)

    ... Share Your Story Give Us Feedback - A + A Transplant Center Search Form Welcome to the Blood & Marrow ... transplant centers for patients with a particular disease. Transplant Center login Username: * Password: * Request new password Join ...

  7. A novel blood-brain barrier co-culture system for drug targeting of Alzheimer's disease: establishment by using acitretin as a model drug.

    Directory of Open Access Journals (Sweden)

    Christian Freese

    Full Text Available In the pathogenesis of Alzheimer's disease (AD the homeostasis of amyloid precursor protein (APP processing in the brain is impaired. The expression of the competing proteases ADAM10 (a disintegrin and metalloproteinase 10 and BACE-1 (beta site APP cleaving enzyme 1 is shifted in favor of the A-beta generating enzyme BACE-1. Acitretin--a synthetic retinoid-e.g., has been shown to increase ADAM10 gene expression, resulting in a decreased level of A-beta peptides within the brain of AD model mice and thus is of possible value for AD therapy. A striking challenge in evaluating novel therapeutically applicable drugs is the analysis of their potential to overcome the blood-brain barrier (BBB for central nervous system targeting. In this study, we established a novel cell-based bio-assay model to test ADAM10-inducing drugs for their ability to cross the BBB. We therefore used primary porcine brain endothelial cells (PBECs and human neuroblastoma cells (SH-SY5Y transfected with an ADAM10-promoter luciferase reporter vector in an indirect co-culture system. Acitretin served as a model substance that crosses the BBB and induces ADAM10 expression. We ensured that ADAM10-dependent constitutive APP metabolism in the neuronal cells was unaffected under co-cultivation conditions. Barrier properties established by PBECs were augmented by co-cultivation with SH-SY5Y cells and they remained stable during the treatment with acitretin as demonstrated by electrical resistance measurement and permeability-coefficient determination. As a consequence of transcellular acitretin transport measured by HPLC, the activity of the ADAM10-promoter reporter gene was significantly increased in co-cultured neuronal cells as compared to vehicle-treated controls. In the present study, we provide a new bio-assay system relevant for the study of drug targeting of AD. This bio-assay can easily be adapted to analyze other Alzheimer- or CNS disease-relevant targets in neuronal cells

  8. A novel blood-brain barrier co-culture system for drug targeting of Alzheimer's disease: establishment by using acitretin as a model drug.

    Science.gov (United States)

    Freese, Christian; Reinhardt, Sven; Hefner, Gudrun; Unger, Ronald E; Kirkpatrick, C James; Endres, Kristina

    2014-01-01

    In the pathogenesis of Alzheimer's disease (AD) the homeostasis of amyloid precursor protein (APP) processing in the brain is impaired. The expression of the competing proteases ADAM10 (a disintegrin and metalloproteinase 10) and BACE-1 (beta site APP cleaving enzyme 1) is shifted in favor of the A-beta generating enzyme BACE-1. Acitretin--a synthetic retinoid-e.g., has been shown to increase ADAM10 gene expression, resulting in a decreased level of A-beta peptides within the brain of AD model mice and thus is of possible value for AD therapy. A striking challenge in evaluating novel therapeutically applicable drugs is the analysis of their potential to overcome the blood-brain barrier (BBB) for central nervous system targeting. In this study, we established a novel cell-based bio-assay model to test ADAM10-inducing drugs for their ability to cross the BBB. We therefore used primary porcine brain endothelial cells (PBECs) and human neuroblastoma cells (SH-SY5Y) transfected with an ADAM10-promoter luciferase reporter vector in an indirect co-culture system. Acitretin served as a model substance that crosses the BBB and induces ADAM10 expression. We ensured that ADAM10-dependent constitutive APP metabolism in the neuronal cells was unaffected under co-cultivation conditions. Barrier properties established by PBECs were augmented by co-cultivation with SH-SY5Y cells and they remained stable during the treatment with acitretin as demonstrated by electrical resistance measurement and permeability-coefficient determination. As a consequence of transcellular acitretin transport measured by HPLC, the activity of the ADAM10-promoter reporter gene was significantly increased in co-cultured neuronal cells as compared to vehicle-treated controls. In the present study, we provide a new bio-assay system relevant for the study of drug targeting of AD. This bio-assay can easily be adapted to analyze other Alzheimer- or CNS disease-relevant targets in neuronal cells, as their

  9. Significance of Establishment of Cord Blood Bank and Its Information Networking Management on Cord Blood Stem Cell Transplantation%脐带血库的建立及其信息网络化管理对脐带血干细胞移植的意义

    Institute of Scientific and Technical Information of China (English)

    刘婷

    2011-01-01

    目的:探讨如何建立脐带血(UCB)库、UCB库信息网络化管理策略及对UCB干细胞移植的意义.方法:通过建立UCB库及UCB库的信息网络化管理,使UCB库在UCB干细胞移植中发挥尽可能大的作用.结果:建立起来的血库切实可行,UCB库信息网络化管理最大限度地发挥了UCB在UCB干细胞移植中的作用.结论:UCB库的建立及其信息网络化管理对UCB干细胞移植意义重大,可最大限度地发挥UCB库的作用.%[ Objective ] To explore how to establish a cord blood bank, information networking management strategies of cord blood bank and its significance on cord blood stem cell transplantation. [ Methods ] In order to make the cord blood bank plays its full role in cord blood stem cell transplantation, the cord blood bank was established and the information networking management was carried out. [ Results]The blood bank is feasible, and umbilical cord blood gets the maximum use in cord blood stem cell transplantation by implementation of information networking management of cord blood bank. [ Conclusion] The establishment of cord blood bank and its information networking management has a great significance on cord blood stem cell transplantation, which can get a maximum effect of cord blood bank.

  10. 血液净化中心信息化管理探讨%Discussion on Information Management of Blood Purification Center

    Institute of Scientific and Technical Information of China (English)

    祁永芳

    2015-01-01

    我院血液净化中心是集医教研于一体的特色科室,已累积透析量为万余人次,随着患者数量、透析时间不断增加,各种医疗数据越来越多。血液净化中心的信息管理既不同于医院门诊患者管理,也不同于住院患者信息管理,无法直接使用住院患者管理系统,所有医疗和管理工作都处于手工方式,严重制<科室治疗和管理发展。现分析我科使用计算机平台后体会到信息化管理优势,该系统提高了血透中心的管理效率,降低了医务人员的工作量,实现了血液净化中心的质量趋势,满足了"以患者为中心"的服务要求[1]。%In our blood purification center is integrating YiJiaoYan featured unit, have accumulated amount of dialysis for more people, as the number of patients, and dialysis time increasing, more and more various kinds of medical data.Blood purification center of information management is dif erent from the hospital outpatient management, it is also dif erent from hospital patient information management, not directly use inpatient management system, al medical and management work in manual mode, restricted department treatment and management development.Now analysis after I use the computer platform realize the informationization management advantages, the system improves the ef iciency of management of hemodialysis center, reduce the workload of medical staf , the tendency of the quality of blood purification center, can meet the requirements of"patient-centered"service[1].

  11. The Effect of Folic Acid Consumption (In Prenatal Care on Blood Pressure Change during Pregnancy in Urban and Rural Health Centers in Eastern Azerbaijan

    Directory of Open Access Journals (Sweden)

    Leila Rasoolpoor-Farzin

    2017-02-01

    Full Text Available Background and Objectives : Preeclampsia is one of the most threatening problems in pregnancy and potentially is followed by preterm birth, miscarriage, low birth weight and maternal mortality. Folic acid supplementation is commonly prescribed for women in child bearing age to reduce the prevalence of neural tube defects. However, its role in pre-eclampsia and hypertension is not proven and is debatable. The aim of this study was to evaluate the influence of folic acid on before pregnancy care on blood pressure in pregnancy. Material and Methods: This retrospective cohort study was conducted as census on all 1939 women referred to receive prenatal care between 2008 and 2013 in rural and urban healthcare centers in Sarab, Bostanabad and Khosroshahr. We compared blood pressure changes in two groups with folic acid consumption and another group, not consuming folic acid. Collected data were filled in the checklist and underwent statistical analysis of descriptive and analytical methods by SPSS 16. Results: The mean age of women in this study was 25.98±5.78 years. Ninety-two percent of mothers had regular consumption of folic acid during pregnancy. The peak period of high blood pressure was reported at weeks 37-35 with 8.2% in systolic blood pressure and diastolic blood pressure at week 37-35 and more than 37 weeks with 1.6%. Systolic and diastolic pressure in mothers taking folic acid was significantly lower (P Conclusion: Folic acid intake during pregnancy, as a part of prenatal care, significantly reduces the incidence of hypertension of pregnancy. During this period, folic acid intake can diminish pre-eclampsia and promote maternal and new born health.

  12. 贵州省血液中心2013年成分血报废原因分析%Analysis of the causes of blood transfusion in the blood center of Guizhou Province in 2013

    Institute of Scientific and Technical Information of China (English)

    张喆

    2015-01-01

    目的:了解血液报废的情况及原因,探讨应对策略与措施。方法:对贵州省血液中心2013年1月~2013年12月,对报废的血液进行统计分析。结果:12个月共报废34211单位,报废率12.10%,其中,乳糜血报废血浆19225单位,报废率6.80%,丙氨酸氨基转移酶(ALT)报废8027单位,报废率2.84%。结论:在成分血制备中,乳糜血浆报废量最大,是非检验报废的首要因素。丙氨酸氨基转移酶(ALT)报废尤其在2月、7月增高,此时间段为贵州省血液中心团体无偿献血采集高峰时间,在采集前加强对团体单位的丙氨酸氨基转移酶(ALT)检测将有可能降低血液报废率。%Objective:to understand the situation and the causes of the blood discarding,and to explore the strategies and measures to deal with it.Methods:to analyze the blood of the blood center of Guizhou province from January 2013 to December 2013.Results:12 months were scrapped 34211,scrap rate 12.10%.Among them,chyle blood scrap plasma 19225 units,scrap rate 6.80%,alanine aminotransferase (ALT)scrap 8027 units,scrap rate of 2.84%.Conclusion:the blood component preparation,chyle plasma scrap is the largest,is the primary factor of non test scrap.Alanine aminotransferase (ALT)was scrapped in particular in February and July, the time period is the peak time of blood collection in Guizhou Province,and the detection of alanine aminotransferase (ALT)in the collection before the acquisition of the group can reduce the rate of blood rejection.

  13. What Is Blood?

    Science.gov (United States)

    ... Foundation for America's Blood Centers ADRP What is blood? PUBLICATIONS EDUCATION PRESS ROOM BLOG CAREERS CONTACT ABC ... for patients who need it. One unit of blood can be separated into the following components: Nearly ...

  14. Establishment and development of experimental teaching center for geographic and oceanographic sciences%地理与海洋科学实验教学中心的建设与发展

    Institute of Scientific and Technical Information of China (English)

    柯长青; 李满春; 王腊春

    2012-01-01

    The development and features of relied discipline of the experimental teaching center for geographic and oceanographic sciences in Nanjing University, and the status and function of experimentation education are introduced. On the basis of management reform of experimental teaching, laboratory and instruments and equipment establishment, and the teachers and textbooks establishment of experimentl teaching, the experimental teaching system is established, including course experimental teaching, outdoor practice education, and scientific technique training. The experimental teaching center for geographic and oceanographic sciences in Nanjing University made a series significant education results, and was approved as an experimental teaching demonstration center in Jiangsu Province.%介绍了南京大学地理与海洋科学实验教学中心依托学科的发展与特色、实验教学的地位和作用.基于实验教学管理机制改革、实验室和仪器设备建设、实验教学队伍与教材建设,构建了课程实验教学、野外实践教学和科研能力训练“三位一体”的实验教学体系,取得了一系列显著的教学成果,并被列入江苏省实验教学示范中心.

  15. 军事物流配送中心选址模型的构建%Establishment of Military Logistics Distribution Center Model

    Institute of Scientific and Technical Information of China (English)

    杨春周; 战希臣; 王慧锦

    2012-01-01

    研究了军事物流配送中心优化选址建模问题.针对当前军事物流配送因为涉及变量多,关联程度强难以进行选址的难题,为加强选址的科学决策,对军事物流配送中心概念进行了界定,在明确军事物流选址的流程、步骤和一定数目的备选配送中心的基础上,采用离散二进制PSO解决配送中心的选择问题,建立了根据粒子群优化算法的军事物流配送中心选址优化模型.通过实例验证,模型构建科学合理,降低了计算的复杂度,优化了选址模型,为解决军事物流选址问题提供了科学的途径和手段.%Site selection of the military logistics distribution center is related to many factors and these factors are highly correlated. In this paper, the process and steps of the military logistics site selection were determined and the alternative locations were provided. Discrete binary particle swarm optimization (PSO) was used to solve the problem of distribution center selection and the optimal model of the site selection about the military logistics distribution cen-ter was built. The model was verified to be scientific and reasonable through an example. Complexity of the computa-tion was reduced and the site selection model was optimized, which provides a new way to solve the site selection of the military logistics.

  16. 电工电子实验教学示范中心建设探索%Exploration of Establishing Electrical and Electronic Experiment Center

    Institute of Scientific and Technical Information of China (English)

    郗艳华; 张辉; 王西明

    2013-01-01

    Students' practical ability and innovation ability can be promoted, the integration of resources sharing can be got, and school-running level and teaching quality can be enhanced by the construction of experimental teaching demonstration center. To improve power of professional applied talents training quality, exploration of the construction of electrical and electronic ex-perimental teaching demonstration center of ideas is provided by constructing the hierarchical experimental teaching system, opti-mizing experiment content, riching teaching methods and means, strengthening the construction of teaching staff and the experi-mental teaching platform construction.%实验教学示范中心建设能推动学生实践能力和创新能力培养,促进资源整合共享,提高学校办学水平和教学质量。该文提出了从构建实验教学平台,改革实验教学体系,优化实验教学方法和手段以及加强师资队伍建设等方面探索电工电子实验教学示范中心建设的思路,为提高电类专业应用型人才培养质量进行探讨。

  17. To Establish Bank of Rare Blood Type to Protect Blood Demand for Clinical Use%建立稀有血型库保障临床用血需求

    Institute of Scientific and Technical Information of China (English)

    杨青成

    2011-01-01

    The paper proposed several practice suggestions: taking suspension red blood cell bank as emergency use, taking frozen red blood cells bank as main usage, and taking floating blood donors bank as supplement, which was an effective method to protect the timely, adequate and safe supply of rare blood type.%总结了建立以悬浮红细胞库为应急、以冰冻红细胞库为主力、以流动献血者库为补充的稀有血型库的实践,认为此举是保障稀有血型血液的及时、足量、安全供应的有效方法.

  18. Storing Blood Cells

    Science.gov (United States)

    1976-01-01

    The National Cancer Institute worked with Goddard Space Flight Center to propose a solution to the blood-cell freezing problem. White blood cells and bone marrow are stored for future use by leukemia patients as a result of Goddard and Jet Propulsion Laboratory expertise in electronics and cryogenics. White blood cell and bone marrow bank established using freezing unit. Freezing unit monitors temperature of cells themselves. Thermocouple placed against polyethylene container relays temperature signals to an electronic system which controls small heaters located outside container. Heaters allow liquid nitrogen to circulate at constant temperature and maintain consistent freezing rate. Ability to freeze, store, and thaw white cells and bone marrow without damage is important in leukemia treatment.

  19. Heterozigose para hemoglobinopatias em doadores de sangue do Centro de Hemoterapia de Sergipe Heterozigosity to hemoglobinopathies in blood donors from the Hemotherapy Center in Sergipe, NE-Brazil

    Directory of Open Access Journals (Sweden)

    Wanessa L. P. Vivas

    2006-12-01

    Full Text Available As hemoglobinopatias, distúrbios geneticamente determinados da hemoglobina (Hb humana, estão presentes com freqüência elevada em várias partes do mundo, sendo que no Brasil as Hb anormais S e C são as mais prevalentes. Com o objetivo de identificar a presença de portadores saudáveis de genes para hemoglobinopatias entre doadores de sangue do Centro de Hemoterapia do Estado de Sergipe (Hemose, foram analisadas 1.345 amostras de doadores de sangue. Em todas as amostras foram realizados eritrograma automatizado e eletroforese de hemoglobina em acetato de celulose utilizando-se tampão Tris-EDTA-Borato pH 8,6. As amostras que apresentaram hemoglobinas anormais foram submetidas a teste de falcização, teste de solubilidade e Cromatografia Líquida de Alta Performance (HPLC. Foram identificadas 76 amostras com hemoglobinas anormais (5,6%, das quais 55 (4,1% com traço falciforme (Hb AS, 19 (1,4% com Hb AC, uma com Hb AD e outra sugestiva de beta-talassemia. Os resultados encontrados demonstram a necessidade de implantação da triagem para hemoglobinopatias entre doadores de sangue, pois desta maneira o receptor de sangue é beneficiado com produto de melhor qualidade, e o doador com a identificação de uma alteração genética que pode vir a se manifestar em seus descendentes.Hemoglobinopathies are genetically determined disorders that present in significant high frequencies in certain parts of the world. Despite of the existence of hundreds of known hereditary hemoglobinopathies, Brazilian studies have demonstrated that abnormal hemoglobins S and C are the most prevalent. With the objective of identifying the profile of hemoglobinopathies of blood donors at the Hemotherapy Center in the State of Sergipe (Hemose, 1345 samples of blood were analyzed. Initially automatic blood testing and electrophoreses in cellulose acetate using a Tris-EDTA-Borate buffer at pH 8.6 were carried out for all samples. Samples that presented with abnormal

  20. Increasing incidence of chronic graft-versus-host disease in allogeneic transplantation: a report from the Center for International Blood and Marrow Transplant Research.

    Science.gov (United States)

    Arai, Sally; Arora, Mukta; Wang, Tao; Spellman, Stephen R; He, Wensheng; Couriel, Daniel R; Urbano-Ispizua, Alvaro; Cutler, Corey S; Bacigalupo, Andrea A; Battiwalla, Minoo; Flowers, Mary E; Juckett, Mark B; Lee, Stephanie J; Loren, Alison W; Klumpp, Thomas R; Prockup, Susan E; Ringdén, Olle T H; Savani, Bipin N; Socié, Gérard; Schultz, Kirk R; Spitzer, Thomas; Teshima, Takanori; Bredeson, Christopher N; Jacobsohn, David A; Hayashi, Robert J; Drobyski, William R; Frangoul, Haydar A; Akpek, Görgün; Ho, Vincent T; Lewis, Victor A; Gale, Robert Peter; Koreth, John; Chao, Nelson J; Aljurf, Mahmoud D; Cooper, Brenda W; Laughlin, Mary J; Hsu, Jack W; Hematti, Peiman; Verdonck, Leo F; Solh, Melhelm M; Norkin, Maxim; Reddy, Vijay; Martino, Rodrigo; Gadalla, Shahinaz; Goldberg, Jenna D; McCarthy, Philip L; Pérez-Simón, José A; Khera, Nandita; Lewis, Ian D; Atsuta, Yoshiko; Olsson, Richard F; Saber, Wael; Waller, Edmund K; Blaise, Didier; Pidala, Joseph A; Martin, Paul J; Satwani, Prakash; Bornhäuser, Martin; Inamoto, Yoshihiro; Weisdorf, Daniel J; Horowitz, Mary M; Pavletic, Steven Z

    2015-02-01

    Although transplant practices have changed over the last decades, no information is available on trends in incidence and outcome of chronic graft-versus-host disease (cGVHD) over time. This study used the central database of the Center for International Blood and Marrow Transplant Research (CIBMTR) to describe time trends for cGVHD incidence, nonrelapse mortality, and risk factors for cGVHD. The 12-year period was divided into 3 intervals, 1995 to 1999, 2000 to 2003, and 2004 to 2007, and included 26,563 patients with acute leukemia, chronic myeloid leukemia, and myelodysplastic syndrome. Multivariate analysis showed an increased incidence of cGVHD in more recent years (odds ratio = 1.19, P < .0001), and this trend was still seen when adjusting for donor type, graft type, or conditioning intensity. In patients with cGVHD, nonrelapse mortality has decreased over time, but at 5 years there were no significant differences among different time periods. Risk factors for cGVHD were in line with previous studies. This is the first comprehensive characterization of the trends in cGVHD incidence and underscores the mounting need for addressing this major late complication of transplantation in future research.

  1. Blood Types

    Science.gov (United States)

    ... maternity. Learn About Blood Blood Facts and Statistics Blood Components Whole Blood and Red Blood Cells Platelets Plasma ... About Blood Blood Facts and Statistics Blood Types Blood Components What Happens to Donated Blood Blood and Diversity ...

  2. Establishment of loop-mediated isothermal amplification (LAMP) for rapid detection of Brucella spp. and application to milk and blood samples.

    Science.gov (United States)

    Song, Liuyan; Li, Juntao; Hou, Shuiping; Li, Xunde; Chen, Shouyi

    2012-09-01

    Brucella spp. are facultative intracellular bacteria that infect humans and animals. In this study, the loop-mediated isothermal amplification (LAMP) was used to detect the Brucella-specific gene omp25. Reaction conditions were optimized as temperature 65°C, reaction time 60 min, Mg(2+) concentration 8.0 mmol/L, polymerase content Bst DNA, 0.5 μL, deoxyribonucleotide concentration 1.6 mmol/L, and inner/outer primer ratio 1:8. The LAMP method was evaluated with 4 Brucella species and 29 non-Brucella bacteria species. Positive reactions were observed on all the 4 Brucella species but not on any non-Brucella species. The limit of detection of the LAMP method was 3.81 CFU Brucella spp. Using the LAMP method, 7 of 110 raw milk samples and 5 of 59 sheep blood samples were detected positive of Brucella spp. Results indicated that LAMP is a fast, specific, sensitive, inexpensive, and suitable method for diagnosis of Brucella spp. infection.

  3. Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes.

    Directory of Open Access Journals (Sweden)

    Bryan S Briney

    Full Text Available A number of antibodies that efficiently neutralize microbial targets contain long heavy chain complementarity determining region 3 (HCDR3 loops. For HIV, several of the most broad and potently neutralizing antibodies have exceptionally long HCDR3s. Two broad potently neutralizing HIV-specific antibodies, PG9 and PG16, exhibit secondary structure. Two other long HCDR3 antibodies, 2F5 and 4E10, protect against mucosal challenge with SHIV. Induction of such long HCDR3 antibodies may be critical to the design of an effective vaccine strategy for HIV and other pathogens, however it is unclear at present how to induce such antibodies. Here, we present genetic evidence that human peripheral blood antibodies containing long HCDR3s are not primarily generated by insertions introduced during the somatic hypermutation process. Instead, they are typically formed by processes occurring as part of the original recombination event. Thus, the response of B cells encoding antibodies with long HCDR3s results from selection of unusual clones from the naïve repertoire rather than through accumulation of insertions. These antibodies typically use a small subset of D and J gene segments that are particularly suited to encoding long HCDR3s, resulting in the incorporation of highly conserved genetic elements in the majority of antibody sequences encoding long HCDR3s.

  4. The conserved barH-like homeobox-2 gene barhl2 acts downstream of orthodentricle-2 and together with iroquois-3 in establishment of the caudal forebrain signaling center induced by Sonic Hedgehog.

    Science.gov (United States)

    Juraver-Geslin, Hugo A; Gómez-Skarmeta, José Luis; Durand, Béatrice C

    2014-12-01

    In this study, we investigated the gene regulatory network that governs formation of the Zona limitans intrathalamica (ZLI), a signaling center that secretes Sonic Hedgehog (Shh) to control the growth and regionalization of the caudal forebrain. Using loss- and gain-of-function, explants and grafting experiments in amphibians, we demonstrate that barhl2 acts downstream of otx2 and together with the iroquois (irx)-3 gene in establishment of the ZLI compartment initiated by Shh influence. We find that the presumptive (pre)-ZLI domain expresses barhl2, otx2 and irx3, whereas the thalamus territory caudally bordering the pre-ZLI expresses barhl2, otx2 and irx1/2 and early on irx3. We demonstrate that Barhl2 activity is required for determination of the ZLI and thalamus fates and that within the p2 alar plate the ratio of Irx3 to Irx1/2 contributes to ZLI specification and size determination. We show that when continuously exposed to Shh, neuroepithelial cells coexpressing barhl2, otx2 and irx3 acquire two characteristics of the ZLI compartment-the competence to express shh and the ability to segregate from anterior neural plate cells. In contrast, neuroepithelial cells expressing barhl2, otx2 and irx1/2, are not competent to express shh. Noteworthy in explants, under Shh influence, ZLI-like cells segregate from thalamic-like cells. Our study establishes that Barhl2 activity plays a key role in p2 alar plate patterning, specifically ZLI formation, and provides new insights on establishment of the signaling center of the caudal forebrain.

  5. 3种不同血瘀证动物模型的建立与评价%The establishment and evaluation of three different kinds of animal model of blood stasis syndrome

    Institute of Scientific and Technical Information of China (English)

    梁耀月; 李佳佳; 董世芬; 张荣; 袁悦莹; 孙建宁

    2016-01-01

    目的:建立痰浊血瘀、气滞血瘀、痰浊+气滞血瘀大鼠模型,研究不同血瘀状态动物模型的特征。方法选用SD大鼠,随机分为正常对照组、高脂饲料组、慢性刺激组( chro-nic unpredictable mild stress,CUMS)、高脂饲料+慢性刺激组,分别采用相应因素干预6周。于2、4、6周动态监测动物体重、旷场行为、血脂和血清皮质酮指标;实验终点(6周)采用小动物超声和左心室插管法检测心功能,采用黏度仪、红细胞变形/聚集测试仪检测血液流变性相关指标。结果与正常对照组大鼠相比,采用高脂饲料、慢性不可预知性刺激后均可引起血瘀状态,对动物的行为学、血脂、心脏功能、血液黏度造成了不同程度的影响,当两因素叠加时,血瘀相关指标变化最明显,表现为:与正常对照组比较,体重明显降低(P<0.01),2周时水平运动、垂直运动、运动时间均减少(P<0.01或 P <0.05),2周、4周时,血清皮质酮上升( P <0.01或P<0.05),4周、6周时TG明显上升(P<0.01)。6周时,血流速度减慢(P<0.01),收缩末期左室前壁、后壁厚度均增厚(P<0.01或P<0.05),舒张期左心室指数上升(P<0.01),左心室最大收缩速率降低(P<0.05),全血黏度上升(P<0.01)。结论高脂饲料喂养和慢性不可预知性刺激均可形成血瘀状态,但是具有不同的特点。当两因素叠加时,动物可明显出现行为学、血液黏度、心脏功能、血脂等指标的异常,可为血瘀证以及相关药物的研究提供依据。%Aim To establish phlegm and blood stasis, qi-stag-nation and blood stasis, phlegm turbid+qi-stagnation and blood stasis model in rats and to study the characteristics of animal models with different blood stasis. Methods SD rats were ran-domly divided into normal group, high fat diet group, chronic unpredictable mild stress group ( CUMS ) and high fat diet +chronic unpredictable mild stress group. Different states

  6. Establishment of Center for Diagnostic Nanosystems

    Energy Technology Data Exchange (ETDEWEB)

    Maher, John [Marshall Univ., Huntington, WV (United States)

    2016-01-26

    Funding from this project was used to develop several “mini-cores” that contained shared equipment that could be used by researchers at Marshall University. Equipment purchased during this project included: a fluorescencent microplate reader, FTIR system, UV-Vis spectrophotometer, and DNA/RNA analyzer. Other deliverables included the funding of several graduate and undergraduate students, postdoctoral fellows and two research assistant professors. Projects supported by this funding included studies performed at the whole animal, organ, cellular and nano level. Several different types of researchers were supported including undergraduates, graduates, postdoctoral fellows and research assistant professors. The main outcomes of this work was the development of new types of nanoparticles that could be used for the treatment of pulmonary arterial hypertension and sepsis. Additional efforts to develop these projects are ongoing.

  7. Defibrotide for Treatment of Severe Veno-Occlusive Disease in Pediatrics and Adults: An Exploratory Analysis Using Data from the Center for International Blood and Marrow Transplant Research.

    Science.gov (United States)

    Strouse, Christopher; Richardson, Paul; Prentice, Grant; Korman, Sandra; Hume, Robin; Nejadnik, Bijan; Horowitz, Mary M; Saber, Wael

    2016-07-01

    Veno-occlusive disease (VOD) is an early and serious complication of hematopoietic cell transplantation (HCT) that is associated with inferior survival, particularly when it is complicated by multiorgan failure (severe VOD). We evaluated the efficacy of defibrotide in the treatment of severe VOD using observational data from the Center for International Blood and Marrow Transplant Research (CIBMTR). Eight thousand three hundred forty-one patients treated by HCT between 2008 and 2011 were identified from the CIBMTR clinical database; 3.2% met criteria for VOD and 1.2% met criteria for severe VOD. Patients with a diagnosis of VOD as reported to the CIBMTR by their transplanting centers, who had no prior history of cirrhosis, and who had a maximum total bilirubin level > 2.0 mg/dL by day +100 post-HCT were selected for study. Severe VOD was defined as VOD occurring in the setting of renal impairment requiring dialysis or any noninfectious pulmonary abnormality. Patients with severe VOD were divided into 2 groups for analysis: those treated with defibrotide (n = 41) and those not treated with defibrotide (n = 55). Patients in the nondefibrotide group were older, were more likely to be male, were more likely to have a history of previous fungal infection, and had a higher proportion of clinically significant pre-existing disease or organ impairment. Survival rate at day +100 was 39% (95% CI, 24.8% to 54.3%) in patients receiving defibrotide and 30.9% (95% CI, 19.5% to 43.6%) in those not receiving defibrotide. Resolution rate of VOD at day +100 was 51% in the defibrotide group and 29% in the nondefibrotide group (difference, 22.1%; 95% CI, 2.6% to 42%). The results of our study are consistent with previously reported experiences with defibrotide, confirm the poor outcome of this syndrome, and suggest defibrotide is effective in the treatment of severe VOD.

  8. ACL-TOP700血凝仪凝血4项正常参考区间的建立%Establishment of normal reference interval for four items of blood coagulation on ACL-TOP Automatic coagulation analyzer

    Institute of Scientific and Technical Information of China (English)

    陈锐; 鲁燕飞; 周志兰; 姚振国; 陈国强

    2015-01-01

    Objective To establish normal reference interval for four items of blood coagulation on ACL‐TOP Automatic coagu‐lation analyzer .Methods The fasting anti‐coagulation blood samples were collected from 1 268 inpatients and people conducted physical examination ,all subjects without liver disease ,history of blood disease and coagulation disfunction .The prothrombin time (PT) ,activated partical prothrombin time(APTT) ,thrombin time(TT) and serum levels of fibrinogen(FIB) were determined by u‐sing ACL‐TOP automatic coagulation analyzer which was producted by America IL company .And data of determination results were used to establish the normal reference intervals of indexes in this laboratory .Results The precision and accuracy of this analy‐zer was good .There were differences of normal reference intervals between which established in this laboratory and which provided by the manufacturer .Conclusion Each laboratory should establish its own normal reference interval ,not blindly refer to reference interval provided by regents manual .%目的:建立ACL‐TOP700全自动血凝分析仪本实验室凝血4项的正常参考区间。方法筛选1268住院患者及门诊体检者,均无肝病、血液病史及出凝血功能障碍,空腹采集其静脉抗凝血。采用美国IL公司生产的ACL‐TOP700全自动血凝分析仪进行凝血酶原时间(PT)、活化部分凝血酶原时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)测定,建立本实验室 PT、APTT、TT、FIB的正常参考区间。结果该仪器精密度、正确度均良好,各参考区间与厂家提供的参考区间有一定的差异。结论各个实验室应建立自己的参考区间,不可盲目引用厂家试剂说明书上提供的正常参考区间。

  9. FAQ: Blood Donation and Organ Transplant

    Science.gov (United States)

    ... Surveillance Software Health Education Public Service Videos Blood Donation & Organ Transplant Recommend on Facebook Tweet Share Compartir ... giving blood, you should tell your blood center. Donation centers try to ensure that donors who recently ...

  10. Establishment and application of viral inactivation/removal technology for blood products%血液制品病毒灭活/去除技术平台的建立与应用

    Institute of Scientific and Technical Information of China (English)

    尹惠琼; 王蕊; 朱凤宣; 王建国; 章金刚

    2015-01-01

    Objective To establish viral inactivation/removal techniques for blood products , and apply them to inacti-vation/removal process validation of blood products .Methods Enveloped and non-enveloped model viruses were propaga-ted.Viral inactivation/removal techniques for blood products ,including solvent/detergent (S/D) treatment, low pH incuba-tion, dry heat method, pasteurization,and nanofiltration, were established.The virus titer was evaluated using cytopathic effects ( CPE) and Spearman and Karber method .The viral inactivation/removal techniques were believed to be effective when LRV≥4.These techniques were used in viral inactivation /removal validation of blood products .Results Enveloped model viruses were inactivated through S/D treatment and the low pH incubation method .Enveloped and non-enveloped model viruses were inactivated through dry heat and pasteurization .Within a certain range of filtration capacity , PPV was removed through nanofiltration .Conclusion The established viral inactivation/removal techniques can be used in viral inactivation/removal process validation of blood products , which can improve viral safety of blood products .%目的:建立血液制品病毒灭活/去除技术并应用于血液制品的病毒灭活/去除工艺验证。方法建立指示病毒库以及S/D处理法、低pH孵放法、干热法、巴氏消毒法、纳米膜过滤法等血液制品病毒灭活/去除技术,采用细胞病变法测定病毒滴度,Spearman和Karber法计算病毒滴度,病毒滴度降低量( LRV)≥4判为有效,对企业的血液制品样品进行病毒灭活/去除验证。结果 S/D处理法和低pH孵放法可有效灭活有包膜指示病毒,干热法和巴氏消毒法可有效灭活有、无包膜指示病毒,纳米膜过滤法可在一定过滤量范围内去除PPV指示病毒。结论所建立的血液制品病毒灭活/去除技术可用于血液制品的病毒灭活/去除工艺验证,以提高血液制品的病毒安全性。

  11. Survey of Blood Collection Centers and Implementation of Guidance for Prevention of Transfusion-Transmitted Zika Virus Infection--Puerto Rico, 2016.

    Science.gov (United States)

    Vasquez, Amber M; Sapiano, Mathew R P; Basavaraju, Sridhar V; Kuehnert, Matthew J; Rivera-Garcia, Brenda

    2016-04-15

    Since November 2015, Puerto Rico has reported active mosquito-borne transmission of Zika virus. Because of the potential for Zika virus to be transmitted through transfusion of blood components, and because a high percentage of persons infected with Zika virus are asymptomatic, the Food and Drug Administration (FDA) recommended that blood collections cease in areas of the United States affected by active vector-borne transmission of Zika virus until laboratory screening of blood donations or pathogen reduction technology (PRT) for treatment of blood components can be implemented. To inform efforts to maintain the safety and availability of the blood supply in Puerto Rico, CDC, in collaboration with the Puerto Rico Department of Health, conducted a rapid assessment of blood collection and use on the island. A total of 139,369 allogeneic red blood cell (RBC) units, 45,243 platelet units, and 56,466 plasma units were collected in or imported to Puerto Rico during 2015, and 135,966 allogeneic RBC units, 13,526 therapeutic platelet units, and 25,775 plasma units were transfused. Because of the potential for local Zika virus transmission in areas with a competent mosquito vector, other areas of the United States should develop plans to ensure local blood safety and adequacy. Blood collection organizations and public health agencies should collaborate to maintain the safety and availability of local blood supplies in accordance with FDA guidance.

  12. Microbial contamination of peripheral blood and bone marrow hematopoietic cell products and environmental contamination in a stem cell bank: a single-center report.

    Science.gov (United States)

    Kozlowska-Skrzypczak, M; Bembnista, E; Kubiak, A; Matuszak, P; Schneider, A; Komarnicki, M

    2014-10-01

    Hematopoietic stem cells (HSC) derived from peripheral blood (PB) and bone marrow (BM) are frequently used for autologous and allogenic transplantations. Establishing quality control at appropriate steps of the stem cell preparation process is crucial for a successful transplantation. Microbial contamination of haematopoietic stem cells is rare but could cause a potentially mortal complication of a stem cells transplantation. We investigated the microbiological contamination of PB (291 donations) and BM (39 donations) products. Microbial cultures of 330 donations between January 2012 and June 2013 were retrospectively analyzed after the collection and preparation steps. The microbiological analysis was performed with an automated system. Hematopoietic stem cells were processed in a closed system. Additionally, in this report the environment of the working areas of stem cell preparation was monitored. We analyzed microbial contamination of the air in a class I laminar air flow clean bench at the time of preparation and in the laboratory once per month. We reported 9 (2.73%) contaminated HSC products. The most frequent bacteria isolated from PB and BM products were Bacillus species. Coagulase-negative staphylococci and Micrococcus species were the most frequent micro-organisms detected in the air microbial control. Microbial control results are necessary for the safety of hematopoietic stem cell products transplantation. Microbial control of hematopoietic stem cell products enables an early contamination detection and allows for knowledgeable decision making concerning either discarding the contaminated product or introducing an efficient antibiotic therapy. Each step of cell processing may cause a bacterial contamination. A minimum of manipulation steps is crucial for increasing the microbial purity of the transplant material. Also, the air contamination control is essential to ensure the highest quality standards of HSC products preparation.

  13. Chemical Security Analysis Center

    Data.gov (United States)

    Federal Laboratory Consortium — In 2006, by Presidential Directive, DHS established the Chemical Security Analysis Center (CSAC) to identify and assess chemical threats and vulnerabilities in the...

  14. Complete blood count reference intervals for healthy Han Chinese adults.

    Directory of Open Access Journals (Sweden)

    Xinzhong Wu

    Full Text Available Complete blood count (CBC reference intervals are important to diagnose diseases, screen blood donors, and assess overall health. However, current reference intervals established by older instruments and technologies and those from American and European populations are not suitable for Chinese samples due to ethnic, dietary, and lifestyle differences. The aim of this multicenter collaborative study was to establish CBC reference intervals for healthy Han Chinese adults.A total of 4,642 healthy individuals (2,136 males and 2,506 females were recruited from six clinical centers in China (Shenyang, Beijing, Shanghai, Guangzhou, Chengdu, and Xi'an. Blood samples collected in K2EDTA anticoagulant tubes were analyzed. Analysis of variance was performed to determine differences in consensus intervals according to the use of data from the combined sample and selected samples.Median and mean platelet counts from the Chengdu center were significantly lower than those from other centers. Red blood cell count (RBC, hemoglobin (HGB, and hematocrit (HCT values were higher in males than in females at all ages. Other CBC parameters showed no significant instrument-, region-, age-, or sex-dependent difference. Thalassemia carriers were found to affect the lower or upper limit of different RBC profiles.We were able to establish consensus intervals for CBC parameters in healthy Han Chinese adults. RBC, HGB, and HCT intervals were established for each sex. The reference interval for platelets for the Chengdu center should be established independently.

  15. The establishment and application of dynamic model of red blood cell suspension's electrolyte changing%红细胞悬浮液电解质动态变化模型的建立及其初步应用

    Institute of Scientific and Technical Information of China (English)

    廖小凤; 谭均强; 高炳谏; 区勇勤

    2013-01-01

    Objective To establish the dynamic model of red blood cell suspension's electrolyte changing of during the storage time. Methods The samples were collected from red blood cell suspensions after it had been preserved 3 days,5 days,7 days,14 days,21 days,28 days,35 days,and 10 samples were collected at each point time,and them testing K+ ,Na+,Cl- ,and analysing the results. Results The concentration of Na+ decreased and then increased in the early stage,but it always been lower than the initial concentration . The concentration of Cl-changed less in the preservation period,which were not significant statistically difference. The concentration of K+had been beyond the scope of normai reference values(3.5~5.5 mmol/mL),as the red blood cell suspension were preserved on 3 days,and K+ increased with the preservation time,but it's rate of rise were differed in different periods. Conclusion To establishe the dynamic model of red blood cell suspension's electrolyte changing are favorable to control blood inventory,and transfusing the red blood stored in 21days are beneficial for reducing the patient's potassium load .%目的研究建立红细胞悬浮液在保存期内电解质动态变化模型。方法在红细胞保存的24h、3d、5d、7d、14 d、21 d、28 d、35 d等8个时间点,分别采样10份,进行K+、Na+、Cl-测定,并对结果进行统计学分析。结果在保存初期内,Na+浓度先下降后上升,但始终比保存初期的Na+浓度要偏低;Cl-浓度在整个保存期内的变化差异无统计学意义;至保存期的第5天,红细胞悬液的K+浓度已经超出正常人参考值范围(3.5~5.5 mmol/mL),且随着保存时间的增加,K+浓度也相应增加,但在保存不同的时段,K+上升的速率存在差异。结论红细胞悬浮液电解质动态变化模型的建立有助于指导血液的库存控制,输注保存21 d内的红细胞悬浮液有利于减轻患者的钾离子负荷。

  16. Relations between a novel, reliable, and rapid index of arterial compliance (PP-HDI) and well-established inidices of arterial blood pressure (ABP) in a sample of hypertensive elderly subjects.

    Science.gov (United States)

    Bergamini, L; Finelli, M E; Bendini, C; Ferrari, E; Veschi, M; Neviani, F; Manni, B; Pelosi, A; Rioli, G; Neri, M

    2009-01-01

    Hypertension is a risk factor for a long-lasting arterial wall-remodelling leading to stiffness. The rapid method measuring the pulse pressure (PP) by means of the tool of Hypertension Diagnostic Instruments (HDI) called PP-HDI, overcomes some of the problems arising with more-time consuming methods, like ambulatory blood pressure monitoring (ABPM), and give information about the elasticity of the arterial walls. We studied the relationship between the PP-HDI, the large artery compliance (LA-C) and small artery compliance (SA-C) and few well-established indices of arterial blood pressure (ABP) in a sample of 75 hypertensive subjects, aged 65 years and over. Significant correlations between LA-C and heart rate (HR), PP-ABPM and PP-HDI were found. SA-C relates with HR and systolic blood pressure (SBP) measured in lying and standing positions. Applying a stepwise regression analysis, we found that LA-C variance stems from PP-HDI and HR, while SA-C variance stems from SBP in lying position. Receiver operator characteristic (ROC) curves for thresholds of PP showed that PP-HDI reached levels of sensitivity/specificity similar to PP-ABPM. In conclusion, surveillance of ABP through hemo-dynamic indices, in particular of SBP, is essential, nevertheless the advantage of this control is not known in an elderly population where the organ damage is already evident. PP needs necessarily an instrumental measurement. The PP-HDI result is similar in reliability with respect to PPABPM, but is more rapid and well applicable in an elderly population.

  17. Establishing MICHCARB, a geological carbon sequestration research and education center for Michigan, implemented through the Michigan Geological Repository for Research and Education, part of the Department of Geosciences at Western Michigan University

    Energy Technology Data Exchange (ETDEWEB)

    Barnes, David A. [Western Michigan University; Harrison, William B. [Western Michigan University

    2014-01-28

    The Michigan Geological Repository for Research and Education (MGRRE), part of the Department of Geosciences at Western Michigan University (WMU) at Kalamazoo, Michigan, established MichCarb—a geological carbon sequestration resource center by: • Archiving and maintaining a current reference collection of carbon sequestration published literature • Developing statewide and site-specific digital research databases for Michigan’s deep geological formations relevant to CO2 storage, containment and potential for enhanced oil recovery • Producing maps and tables of physical properties as components of these databases • Compiling all information into a digital atlas • Conducting geologic and fluid flow modeling to address specific predictive uses of CO2 storage and enhanced oil recovery, including compiling data for geological and fluid flow models, formulating models, integrating data, and running the models; applying models to specific predictive uses of CO2 storage and enhanced oil recovery • Conducting technical research on CO2 sequestration and enhanced oil recovery through basic and applied research of characterizing Michigan oil and gas and saline reservoirs for CO2 storage potential volume, injectivity and containment. Based on our research, we have concluded that the Michigan Basin has excellent saline aquifer (residual entrapment) and CO2/Enhanced oil recovery related (CO2/EOR; buoyant entrapment) geological carbon sequestration potential with substantial, associated incremental oil production potential. These storage reservoirs possess at least satisfactory injectivity and reliable, permanent containment resulting from associated, thick, low permeability confining layers. Saline aquifer storage resource estimates in the two major residual entrapment, reservoir target zones (Lower Paleozoic Sandstone and Middle Paleozoic carbonate and sandstone reservoirs) are in excess of 70-80 Gmt (at an overall 10% storage efficiency factor; an approximately

  18. The establishment of the School of Public Health at the State University of New York, Downstate Medical Center: the first nationally accredited school of public health in a public university in New York City.

    Science.gov (United States)

    Imperato, Pascal James; LaRosa, Judith H; Kavaler, Florence; Benker, Karen; Schechter, Leslie

    2011-02-01

    The State University of New York (SUNY), Downstate Medical Center initiated a Master of Public Health (MPH) degree program in July 2001 following planning efforts that began in 1995. Twelve students entered the program in June 2002, and currently some 110 MPH students and 12 Doctor of Public Health (DrPH) students are enrolled. This article describes the long and complex process of transforming the original MPH degree program, with its single focus on urban and immigrant health, with a student enrollment of 12 and 8 full-time faculty, into a school of public health with a large student enrollment of 122 students, 25 full-time faculty, five MPH degree tracks, and four DrPH degree tracks. The process of establishing the SUNY Downstate School of Public Health in 2009 from its inception as an MPH program in 2001 spanned a period of 8 years. This process was guided by a commitment to two basic principles. The first was to maintain the original 2005 program accreditation by the Council on Education for Public Health (CEPH). The second was to sequentially secure accreditation for all subsequent four MPH and four DrPH degree tracks through CEPH's procedure of substantive change approval. This policy assured continuous national CEPH accreditation of the original Urban and Immigrant Health MPH degree track and all added degree programs. The 5-year period following the initial CEPH accreditation of the MPH program in 2005 was one of intense development during which all of the essential elements for CEPH accreditation of a school of public health were put into place. This rapid development was made possible by the vision and full support of Downstate's president, John C. LaRosa, MD, FACP, and the dedicated efforts of many. This included the students, faculty, staff, and administrators of the School of Public Health, the school's Community Advisory Group, several external advisors, and many in the medical center's Central Administration, College of Medicine, School of Graduate

  19. 产前非创伤性检测胎儿kidd血型基因型方法的建立及其应用%Establishment of noninvasive prenatal diagnosis method for fetal Kidd blood group genotype and its application

    Institute of Scientific and Technical Information of China (English)

    秦斐; 何吉; 王芳; 陈舒; 刘晋辉; 朱发明; 吕杭军; 严力行

    2011-01-01

    目的:利用孕妇血浆中游离胎儿DNA建立产前非创伤性诊断Kidd血型基因型的实时荧光PCR技术(RQ-PCR).方法:采用QIAamp试剂盒抽提孕妇血浆DNA,利用短串联重复序列(STR)确认提取物存在胎儿DNA,利用RQ-PCR检测胎儿Kidd基因型.采用血清学方法检测婴儿脐带血Kidd表型,回顾性评价基因分型方法的准确性.结果:在182例孕妇中筛选出96例纯合子Kidd表型,进一步通过鉴定其婴儿脐带血Kidd表型,从中筛选得到46例标本孕妇纯合子表型而婴儿脐带血JK(a+b+)表型.在这46例孕妇血浆DNA标本中能检出父源性等位基因的标本为38例,孕妇表型分别为6例JK(a+b-)和32例JK(a-b+).38例孕妇血浆DNA标本用RQ-PCR法均检测到了孕妇所不具备的JK * B或JK*A父源性等位基因,其结果与婴儿脐带血Kidd表型相吻合.结论:本实验建立的RQ-PCR非创伤性产前诊断胎儿Kidd血型基因型是可行的,当孕妇为纯合子时可通过产前非创伤性基因分型辅助诊断和预防新生儿溶血病.%Objective:To establish the real time fluorescence quantitative PCR (RQ -PCR) of noninvasive prenatal diagnosis for fetal Kidd blood group genotype from cell -free fetal DNA in maternal plasma. Methods: QIAamp DNA Kit was used to extract DNA from maternal plasma samples. The existence of fetal DNA was confirmed by short tandem repeat (STR) technique.The fetal Kidd genotype was examined by RQ - PCR from cell - free fetal DNA in maternal plasma. The Kidd phenotype of fetal cord blood samples was determined by serological assay and the concordance of the results between RQ - PCR and serological assay were analyzed. Results: 96 samples with Kidd homozygote phenotypes were chosen from 182 maternal peripheral blood samples. 46 samples with mother homozygote phenotype and fetal Jk( a + b + ) phenotype were obtained by further analyzed the Kidd phenotypes from fetal cord blood samples. 38 samples were found to show the paternally inherited

  20. Establishment of radiation dose-response curve based on in vitro irradiation of peripheral blood samples by X-ray%离体人外周血血X射线照射后剂量效应曲线的建立

    Institute of Scientific and Technical Information of China (English)

    李广伟; 李峰生

    2012-01-01

    目的 建立准确估算受辐射照射者辐射剂量的方法.方法 采用X射线照射离体人外周血,一步法培养外周血淋巴细胞56 h后收获制片,检测染色体"双着丝粒(dic)+环(r)"畸变率,拟合剂量效应曲线.结果 畸变率随照射剂量增加而增加,存在明显的剂量效应,剂量效应曲线回归方程为y=0.020 8x2+0.102 8x-0.024 8,r2=0.995 3(P<0.05).结论 通过建立X射线照射离体人外周血后的剂量效应曲线,能准确估算受照辐射剂量.%Objective To establish the method of estimating accurately radiation dose of the individuals exposed to ionizing-radi-ation. Methods The blood samples in vitro were irradiated by X-ray,then cultured using one-step method for 56 hours. According to the chromosomal aberration rate(including dicentric chromosome and ring) , radiation dose-response curve was fitted. Results The chromosomal aberration rate induced by the different radiation doses increased along with the increase of radiation dose, and there was an apparent dose-response relationship,the radiation dose-response curve regression equation:y=0. 020 8x2+0. 102 8x-0. 024 8. Conclusion The dose of the individual exposed to ionizing-radiation could be estimated accurately according to the radiation dose-response curve that might be fitted by the blood samples in vitro irradiated by X-ray.

  1. Blood sugar test - blood

    Science.gov (United States)

    ... blood glucose level ( hypoglycemia ) may be due to: Hypopituitarism (a pituitary gland disorder) Underactive thyroid gland or ... tonic-clonic seizure Glucagon blood test Glucagonoma Hyperthyroidism Hypopituitarism Hypothyroidism Insulinoma Low blood sugar Multiple endocrine neoplasia ( ...

  2. Association of changes in the use of board-certified critical care intensivists with mortality outcomes for trauma patients at a well-established level I urban trauma center

    Directory of Open Access Journals (Sweden)

    Petitti Diana

    2012-03-01

    Full Text Available Abstract Background An intensivist-directed Intensive Care Unit is a closed-model unit in which a physician formally trained in critical care plays a leadership role in patient management. In the last decade, there has been a move toward closed Intensive Care Units. The purpose of this evaluation was to assess the association of changes in the use of intensivists to a closed-model with mortality outcomes in injured patients seen in a long-established urban Level I Trauma Center. Methods This analysis used data from the Scottsdale Healthcare Osborn Medical Center trauma registry from January 1, 2002-December 31, 2008. Mortality prior to hospital discharge was compared in the pre-intensivist (intensivists were not employed and did not provide care, partial intensivist (intensivists were employed and provided care during some Intensive Care Unit shifts and full-time intensivist (intensivists were employed and provided care in the Intensive Care Unit full time periods. Multiple logistic regression analysis was used to estimate odds ratios for mortality adjusting for patient characteristics and injury severity for the partial intensivist and full-time intensivist periods compared with the pre-intensivist period. Results Of 18,918 patients, 365 (1.9% died before hospital discharge. After adjustment for demographic factors and injury severity score, for all patients, odds ratios comparing the partial intensivist and full-intensivist periods with the pre-intensivist period were 0.84 (95% confidence interval 0.64-1.11 and 0.99 (95% confidence interval 0.69-1.41. In patients with an injury severity score 16-24, the adjusted OR for death was 0.20 (95% CI 0.07-0.58 comparing the partial-intensivist with the pre-intensivist period and 0.30 (95% CI 0.11-0.88 comparing the full-time intensivist period with the pre-intensivist period. For patients age 65 + years, compared with the pre-intensivist period, odds ratio were 0.51 (95% confidence interval 0

  3. Combination of rituximab with autologous peripheral blood stem cell transplantation for treatment of diffuse large B-cell lymphoma:a single-center experience

    Institute of Scientific and Technical Information of China (English)

    梁赜隐

    2013-01-01

    Objective To investigate whether incorporation of rituximab into high-dose chemotherapy with autologous peripheral blood stem cell transplantation(auto-PBSCT) could improve the survival of patients with diffuse large B-cell lymphoma(DLBCL),and evaluate the safety of

  4. 血站供电应急预案的实现%Realization of Power-supply Emergency Plan in Blood Center

    Institute of Scientific and Technical Information of China (English)

    张晋

    2011-01-01

    This paper provides an overview about realization of emergency plan and design and lectotype of main equipment of Qingdao Blood Station.%本文扼要介绍了青岛血站供电应急预案实现以及主要设备的设计、选型.

  5. Center Blood Stations Concrete Measures and Experience of Implementing Total Quality Management%中心血站实施全面质量管理的具体措施与体会

    Institute of Scientific and Technical Information of China (English)

    韩秀华

    2015-01-01

    Objective The ministry of health "blood stations and the quality control standard", "blood stations management method" and "blood stations laboratory quality management norms" enacted one after another, after the author's station set up the management organization, continuously improving CaiGongXie and service quality management system, to ensure the clinical safety of blood in the city. Seriously implement the blood stations quality management standard and requirement, strengthen the quality management of central blood stations, continuously improve the quality of blood stations in our country.Methods Applying total quality management measures to center management of blood stations, sum up experience.ResultsAfter the implementation of total quality management measures, central blood stations work significantly lower incidence of errors, increased blood unit satisfaction.Conclusion China's ministry of health of blood stations related specification method the promulgation and implementation of quality management puts forward strict requirements on the work quality of blood stations, most blood stations began applying total quality management measures to blood stations, and has obtained remarkable achievement.%目的:卫生部《血站质量管理规范》,《血站管理办法》和《血站实验室质量管理规范》相继颁布实施后,笔者所在站成立了管理组织,持续完善采供血和服务质量管理体系,保证了全市区的临床安全用血。认真贯彻血站质量管理规范和要求,加强对中心血站的质量管理,不断提高我国血站工作质量。方法将全面质量管理措施应用于中心血站的管理工作,总结体会。结果实施全面质量管理措施后,中心血站的工作差错发生率明显降低,用血单位满意度明显上升。结论我国卫生部关于血站质量管理相关规范办法的颁布和实施对我国血站的工作质量提出了严格要求,多数血站开始

  6. 气虚血瘀型Corti器毛细胞损伤动物模型的建立%Establishing hair cell damage model in the animal Corti organ with Qi deficiency and blood stasis

    Institute of Scientific and Technical Information of China (English)

    彭桂原; 李松键; 杨黎; 杨朝杰; 谭串

    2016-01-01

    背景:随着中医药对耳鸣耳聋的疗效越来越受到重视,但对其机制尚缺乏系统深入的研究,利用动物模型进行中医药治疗耳鸣耳聋的机制探索是非常有意义的研究方向。  目的:建立一种气虚血瘀证型的Corti器毛细胞损伤动物(豚鼠)模型并评价其效果。  方法:12只成年豚鼠按随机数字表法分为正常对照组和造模组。造模组首先采用改良耗气破气加饥饱失常法处理15 d进行气虚造模,之后以光化学反应法复制血瘀Corti器毛细胞损伤模型;正常对照组不干预。造模后检测两组豚鼠血清的D-木糖浓度,行耳声发射DPOAE测试,并观察光镜下耳蜗组织形态。  结果与结论:①与正常对照组相比,造模组血清D-木糖浓度较低(P OBJECTIVE:To establish hair cel damage model in the Corti organ with Qi deficiency and blood stasis in guinea pigs, and to assess its effects. METHODS:Twelve adult guinea pigs were randomly divided into normal control and model groups by random number table method. Guinea pigs in the model group were firstly treated with the modified relieving stagnated Qi and abnormal starvation for 15 days to model Qi deficiency, and then stimulated hair cel damage with blood stasis by photochemical induction. The controls received no intervention. Subsequently, the detection of serum D-xylose content and DPOAE test were performed, and the cochlea morphology was observed under light microscope. RESULTS AND CONCLUSION:(1) The serum D-xylose content in the model group was significantly lower than that in the normal control group (P<0.01). (2) DPOAE test revealed that the amplitudes of 1 560 and 3 125 Hz in the model group were lower than those in the normal control group and before modeling (P<0.01). (3) In the model group, hemangiectasis and microthrombosis appeared in the spiral ligament, microvascular basement membrane and modiolus capil aries, and stria vascularis

  7. A MULTI-CENTER CLUSTER-RANDOMIZED TRIAL OF A MULTI-FACTORIAL INTERVENTION TO IMPROVE ANTIHYPERTENSIVE MEDICATION ADHERENCE AND BLOOD PRESSURE CONTROL AMONG PATIENTS AT HIGH CARDIOVASCULAR RISK (The COM99 study)*

    Science.gov (United States)

    Pladevall, Manel; Brotons, Carlos; Gabriel, Rafael; Arnau, Anna; Suarez, Carmen; de la Figuera, Mariano; Marquez, Emilio; Coca, Antonio; Sobrino, Javier; Divine, George; Heisler, Michele; Williams, L Keoki

    2010-01-01

    Background Medication non-adherence is common and results in preventable disease complications. This study assesses the effectiveness of a multifactorial intervention to improve both medication adherence and blood pressure control and to reduce cardiovascular events. Methods and Results In this multi-center, cluster-randomized trial, physicians from hospital-based hypertension clinics and primary care centers across Spain were randomized to receive and provide the intervention to their high-risk patients. Eligible patients were ≥50 years of age, had uncontrolled hypertension, and had an estimated 10-year cardiovascular risk greater than 30%. Physicians randomized to the intervention group counted patients’ pills, designated a family member to support adherence behavior, and provided educational information to patients. The primary outcome was blood pressure control at 6 months. Secondary outcomes included both medication adherence and a composite end-point of all cause mortality and cardiovascular-related hospitalizations. Seventy-nine physicians and 877 patients participated in the trial. The mean duration of follow-up was 39 months. Intervention patients were less likely to have an uncontrolled systolic blood pressure (odds ratio 0.62; 95% confidence interval [CI] 0.50–0.78) and were more likely to be adherent (OR 1.91; 95% CI 1.19–3.05) when compared with control group patients at 6 months. After five years 16% of the patients in the intervention group and 19% in the control group met the composite end-point (hazard ratio 0.97; 95% CI 0.67–1.39). Conclusions A multifactorial intervention to improve adherence to antihypertensive medication was effective in improving both adherence and blood pressure control, but it did not appear to improve long-term cardiovascular events. PMID:20823391

  8. Establishment of a Rapid Method for Extracting Human Genomic DNA from Peripheral Clotted Blood%一种快速、经济提取外周凝血基因组DNA方法的建立

    Institute of Scientific and Technical Information of China (English)

    许丽娟; 马骁; 王洋阳; 王静; 潘晴; 刘梅

    2011-01-01

    Objective: To establish a rapid, economical method for extracting genotnic DNA from peripheral clotted blood. Methods: Explore a optimum homogenate condition, homogenate the clotted blood, extracting the genomic DNA by KI method. Use agarose gel electrophoresis, single PCR and multiplex PCR detect the genomic DNA extraction yield and quality. And compared with the traditional extraction methods, Proteinase K digestion method and KI method which extract DNA from anti-coagulated blood. Results: The optimum homogenate condition is 39000 rmp and 15 seconds. The genomic DNA was extracted under this condition has good integrity. There is no significant difference of purity and yield between this method and Proteinase K digestion and KI method. Single PCR and multiplex PCR also obtained good amplification results. Conclusion: Compared with traditional extraction methods (Proteinase K digestion method),this method can save time and cost, which can extract DNA rapidly,economical and effectively,and can be used in clinical and research analysis, and can solve the blood genomic DNA sources of some of the research institutions.%目的:建立一种经济、快速且高质量提取人体外周凝血DNA的方法.方法:摸索最佳的匀浆条件,对外周凝血块进行匀浆,采用KI法对匀浆液进行基因组DNA的提取,通过凝胶电泳、单重PCR和多重PCR检测凝血基因组DNA的提取产量和质量,并分别与常规的凝血基因组DNA提取方法,即蛋白酶K消化法,以及提取抗凝血基因组DNA的KI法进行比较分析.结果:最佳的匀浆条件为:39000 rmp,15秒.在此条件下提取的基因组DNA完整性好,纯度和产量与蛋白酶K消化法提取凝血DNA和KI法提取抗凝血DNA的结果相比,没有统计学差异.单重PCR和多重PCR也获得了理想的扩增结果.结论:与常规的外周凝血提取方法相比(蛋白酶K消化法),本方法节省了时间和成本,能快速、经济、有效地提取外周凝血基因组DNA,可

  9. Establishment and Application of a Noninvasive Method for Estimation of Total Haemoglobin Content in Red Blood Cell Components%非侵入性评估红细胞成分血中血红蛋白总量方法的建立及应用

    Institute of Scientific and Technical Information of China (English)

    伍伟健; 黄敏桃; 罗媚佳; 庞晓丹; 余晋林

    2012-01-01

    Objective To establish and apply a noninvasive method for estimation of total hemoglobin (Hb)content in red blood cell components to improve the level of standardization of transfusion.Methods Two hundred and thirty leukocyte-reduced red blood cells were elected as research objects,which were randomly selected in stock bloods of Foshan Blood Station.The weight,volume and Hb concentration of one hundred and thirty red blood cell components were tested.The correlation between Hb content with weight of red blood cell components was analyzed.A linear regression model was used to assess the relationship.Regression equation was built. One hundred red blood cell components were tested and analysed by the regression equation.The results were compared with the actual detection value in order to verify the reliability of the method we built. Results There was a positive correlativity of the weight and Hb concentration of red blood cell components(r=0.971,P<0.001) ;The regression equation was y=0.1913x-2.9373,y was Hb concentration,x was weight of red blood cell components.Linear regression analysis results showed that the weight was closely related to Hb concentration of red blood cell components.Partial regression value(b)was -2.9373 and 0.1913(r2 =0.944,df=128,F=2138.12;P<0.01).The estimation of total Hb content in one hundred red blood cell components showed that the assessment and the actual results were no significant differences(P>0.05).Conclusions The noninvasive method for estimation of total Hb content in red blood cell components was simple,safe,reliable and contributed to improve the level of standardization of transfusion. But it need to be confirmed by a multi-center and large sample and randomized controlled research before popularization in transfusion.%目的 探讨建立并应用一种非侵入性准确评估红细胞成分血中血红蛋白(Hb)总量的方法,以提高临床输血标准化水平.方法 自本血站库存血液中,随机抽取230袋

  10. 论在杭州设立国家级茶叶拍卖交易中心的必要性和可行性%The necessity and feasibility auction center to establish a national tea in Hangzhou

    Institute of Scientific and Technical Information of China (English)

    孙传成; 张玉富; 郑斌

    2012-01-01

    Auction is a mainstream in the international tea trade. As a leading power of tea production, it is urgent for China to establish the institution of tea auction to deal with problems that endangered its industry development caused by the lagged behind of tea transaction mode, .such as the lost of pricing power, mismatching between export price and tea value, emerging tea safety problems, increasing risk of tea enterprises management. As a big province of tea production, Zhejiang should make some breakthrough in the model transformation of tea trade. The tea industry of Zhejiang has a strong industrial base as well as a solid market foundation, and has remarkable location superiority. It has researched on the tea auction market for many years, and the tea auction trade has already started. It will have comparative advantages and priority effects in the new economic tide. Besides, the government of Zhejiang attaches great importance to tea auction market, and relevant departments give substantial support to it. Still, Hangzhou city is the national center of tea science and education. This paper deemed Hangzhou as the best choice to set up the national tea auction trading center.%拍卖是国际主流的茶叶交易方式。作为产茶大国的中国,急需建立茶叶拍卖交易制度来应对由于交易方式落后带来的定价权丢失、出口价与茶叶价值、茶叶安全问题层出、茶叶企业经营风险加大等行业发展问题。作为产茶大省的浙江理应在转变茶叶交易方式上有突破性的作为。本文从浙江茶叶产业基础雄厚、浙江茶叶专业市场基础坚实且区位优势显著、对茶叶拍卖市场研究多年,茶叶拍卖交易已经起步、浙江在新经济浪潮中具有比较优势和先发效应、浙江政府高度重视,各有关部门大力支持、浙江杭州是全国茶叶科教经济文化中心_的角度论证,认为浙江杭州是设立国家级茶叶拍卖交易中心的首选地。、

  11. The Clinical Significance of Establishing Wound Treatment Center and Developing Outpatient Nursing%建立创面治疗中心及开展护理门诊的临床意义

    Institute of Scientific and Technical Information of China (English)

    任素琴; 孟凡慧; 王玉英

    2016-01-01

    随着临床业务拓展的迫切需求,开展专科护理门诊是护理学科发展的必然趋势.某院在借鉴国内外多家医院开设护理门诊经验基础上,经过充分的专家论证,在新门诊大楼内增设了创面治疗中心,并开设了伤口护理门诊、造口/失禁护理门诊、经外周中心静脉置管(PICC)护理门诊等专科护理门诊.其合理的布局设置,科学的功能分区,规范的工作流程,通过一支专业化护理队伍的全方位建设,使其诊疗范畴不断扩增.设立的伤口护理与造口/失禁护理门诊不但提高了患者伤口愈合速度,缩短了伤口愈合时间,而且通过承担出院患者的延续护理服务,降低了平均住院日,加快了病房床位周转,同时提升了护理人员的社会价值感,获得了较好的经济效益和社会效益.%As the urgent needs of clinical business development, the carrying out of outpatient nursing is the inevitable trend of the disciplinary development. On the basis of development of outpatient nursing experience from home and abroad, as well as full demonstration of experts, we added wound therapy center in the new outpatient building and opened a wound care clinic, ostomy/incontinence care clinic, peripherally inserted central venous catheter(PICC) nursing specialist care in outpatient clinics. The reasonable layout, the scientific function, standardized work process through a full range of professional nursing team construction, its diagnosis and treatment scope was continuously expanding. The establishment of wound nursing and ostomy/incontinence outpatients nursing not only improved the speed of wound healing, shortened the healing time, and reduced the average length of stay, speeded up the ward beds turnover and enhanced the social value of the nursing staff, and received good economic and social benefits at the same time.

  12. 全血中伤寒沙门菌RT-LAMP检测方法的建立%Establishment of RT-LAMP assay to detect Salmonella Typhi in blood

    Institute of Scientific and Technical Information of China (English)

    樊粉霞; 王淑京; 娄静; 陈建才; 聂艳妮; 阚飙; 闫梅英

    2012-01-01

    Objective To establish reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay to detect Salmonella Typhi in blood. Methods A set of six specific primers recognizing distinct regions of fliC-d gene of S. Typhi were designed and modified to establish RT-LAMP assay and the specificity and sensitivity of RT-LAMP with RNA as template were evaluated and verified by detecting cultured Salmonella and non-Salmonella strains in 48 serotypes, the non-Salmonella strains causing diarrhea and the strains of 8 bacteria inducing bacteremia with fever as main symptom. The simulated blood specimens supplemented with S. Typhi were tested with RT-LAMP assay, and the detection limit of RT-LAMP was compared with that of real-time PCR. Results The RT-LAMP assay successfully detected fliC-d gene of S. Typhi within 30 to 60 minutes at 65 t. Totally 44 strains of S. Typhi were detected to be positive. Except 4 rare serotypes of non-salmonella were positive in amplification, the amplification of the strains of non-Salmonella in 30 serotypes, the strains of 5 pathogens causing diarrhea and the strains of 8 bacteria causing bacteremia with fever as main symptom were negative. In the detection of total RNA from pure cultured isolates, the detection limit of RT-LAMP was 0.5 pg per reaction (97copies per reaction). In the extracting nucleotide from simulated blood, the sensitivity was 1 cfu /ml, which was 100 fold higher than that of real time PCR. Conclusion The RT-LAMP assay for detecting 5. Typhi with high sensitivity and specificity was established, which would be suitable for rapid diagnosis of S. Typhi infection and identifying pathogen of fever with unknown origin , and can be used in early diagnosis, prevention/control and treatment of typhoid fever.%目的 建立反转录-环介导等温核酸扩增(RT-LAMP)方法特异检测伤寒沙门菌.方法 针对伤寒沙门菌fliC-d基因设计6条特异性引物,通过优化反应条件,建立检测

  13. Program for establishing long-time flight service performance of composite materials in the center wing structure of C-130 aircraft. Phase 5: flight service and inspection. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Kizer, J.A.

    1981-10-01

    Inspections of the C-130 composite-reinforced center wings were conducted over the flight service monitoring period of more than six years. Twelve inspections were conducted on each of the two C-130H airplanes having composite reinforced center wing boxes. Each inspection consisted of visual and ultrasonic inspection of the selective boron-epoxy reinforced center wings which included the inspection of the boron-epoxy laminates and the boron-epoxy reinforcement/aluminum structure adhesive bondlines. During the flight service monitoring period, the two C-130H aircraft accumulated more than 10,000 flight hours and no defects were detected in the inspections over this period. The successful performance of the C-130H aircraft with composite-reinforced center wings allowed the transfer of the responsibilities of inspecting and maintaining these two aircraft to the U. S. Air Force.

  14. Evaluation of a biosimilar granulocyte colony-stimulating factor (filgrastim XM02 for peripheral blood stem cell mobilization and transplantation: a single center experience in Japan

    Directory of Open Access Journals (Sweden)

    Yoshimura H

    2017-01-01

    Full Text Available Hideaki Yoshimura, Masaaki Hotta, Takahisa Nakanishi, Shinya Fujita, Aya Nakaya, Atsushi Satake, Tomoki Ito, Kazuyoshi Ishii, Shosaku Nomura First Department of Internal Medicine, Kansai Medical University, Hirakata, Osaka, Japan Background: Biosimilar granulocyte colony-stimulating factor (G-CSF has recently been introduced into clinical practice. G-CSFs are used to mobilize CD34+ cells and accelerate engraftment after transplantation. However, in Asia, particularly in Japan, data for peripheral blood stem cell (PBSC mobilization by this biosimilar G-CSF are currently lacking. Therefore, the clinical efficacy and safety of biosimilar G-CSF for hematopoietic stem cell transplantation needs to be evaluated in a Japanese context.Materials and methods: The subjects included two groups of patients with malignant lymphoma and multiple myeloma. All patients received chemotherapy priming for the mobilization of PBSCs. All patients were treated with chemotherapy followed by the administration of either the biosimilar G-CSF, filgrastim XM02 (FBNK, or the originators, filgrastim, or lenograstim.Results: There were no significant differences among FBNK, filgrastim, and lenograstim treatments in the numbers of CD34+ cells in harvested PBSCs, the scores for granulocyte/macrophage colony forming units, or for malignant lymphoma and multiple myeloma patients evaluated as separate or combined cohorts. In addition, there were no significant differences in safety, side effects, complications, or the time to engraftment after autologous hematopoietic stem cell transplantation.Conclusion: Biosimilar FBNK shows the same efficacy and safety as originator G-CSFs for facilitating bone marrow recovery in Japanese malignant lymphoma and multiple myeloma patients undergoing stem cell transplantation. In addition, it is less expensive than the originators, reducing hospitalization costs. Keywords: G-CSF, biosimilar, peripheral blood stem cell, hematological

  15. Empowerment, motivation, and medical adherence (EMMA: the feasibility of a program for patient-centered consultations to support medication adherence and blood glucose control in adults with type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Varming AR

    2015-09-01

    Full Text Available Annemarie Reinhardt Varming,1 Ulla Møller Hansen,1 Gudbjörg Andrésdóttir,2 Gitte Reventlov Husted,1 Ingrid Willaing1 1Patient Education Research, 2Complications Research, Steno Diabetes Center, Gentofte, Denmark Purpose: To explore the feasibility of a research-based program for patient-centered consultations to improve medical adherence and blood glucose control in patients with type 2 diabetes.  Patients and methods: The patient-centered empowerment, motivation, and medical adherence (EMMA consultation program consisted of three individual consultations and one phone call with a single health care professional (HCP. Nineteen patients with type 2 diabetes completed the feasibility study. Feasibility was assessed by a questionnaire-based interview with patients 2 months after the final consultation and interviews with HCPs. Patient participation was measured by 10-second event coding based on digital recordings and observations of the consultations.  Results: HCPs reported that EMMA supported patient-centered consultations by facilitating dialogue, reflection, and patient activity. Patients reported that they experienced valuable learning during the consultations, felt understood, and listened to and felt a trusting relationship with HCPs. Consultations became more person-specific, which helped patients and HCPs to discover inadequate diabetes self-management through shared decision-making. Compared with routine consultations, HCPs talked less and patients talked more. Seven of ten dialogue tools were used by all patients. It was difficult to complete the EMMA consultations within the scheduled time.  Conclusion: The EMMA program was feasible, usable, and acceptable to patients and HCPs. The use of tools elicited patients’ perspectives and facilitated patient participation and shared decision-making. Keywords: type 2 diabetes, adherence, participation, dialogue, health education, self-management

  16. The Impact of Obesity and Insulin Resistance on Iron and Red Blood Cell Parameters: A Single Center, Cross-Sectional Study

    Directory of Open Access Journals (Sweden)

    Esma Altunoğlu

    2014-03-01

    Full Text Available OBJECTIVE: Obesity and iron deficiency (ID are the 2 most common nutritional disorders worldwide causing significant public health implications. Obesity is characterized by the presence of low-grade inflammation, which may lead to a number of diseases including insulin resistance (IR and type 2 diabetes. Increased levels of acute-phase proteins such as C-reactive protein (CRP have been reported in obesity-related inflammation. The aim of this study was to investigate the impact of obesity/IR on iron and red blood cell related parameters. METHODS: A total of 206 patients and 45 control subjects of normal weight were included in this crosssectional study. Venous blood samples were taken from each patient to measure hemoglobin (Hb, serum iron (Fe, ironbinding capacity (IBC, ferritin, CRP, fasting blood glucose, and fasting insulin. Body mass index (BMI and waist-to-hip ratio (WHR were calculated for each patient. IR was determined using the HOMA-IR formula. RESULTS: Subjects were divided into 3 groups according to BMI. There were 152 severely obese (BMI: 42.6±10.1, 54 mildly obese (BMI: 32.4±2.1, and 45 normal-weight (BMI: 24.3±1.3 patients. Hb levels in severely obese patients and normal controls were 12.8±1.3 g/dL and 13.6±1.8 g/dL, respectively. We found decreasing Fe levels with increasing weight (14.9±6.9 μmol/L, 13.6±6.3 μmol/L, and 10.9±4.6 μmol/L for normal controls and mildly and severely obese patients, respectively. Hb levels were slightly lower in patients with higher HOMA-IR values (13.1±1.5 g/dL vs. 13.2±1.2 g/dL; p=0.36. Serum iron levels were significantly higher in the group with low HOMA-IR values (13.6±5.9 μmol/L vs. 11.6±4.9 μmol/L; p=0.008. IBC was found to be similar in both groups (60.2±11.4 μmol/L vs. 61.9±10.7 μmol/L; p=0.23. Ferritin was slightly higher in patients with higher HOMA-IR values (156.1±209.5 pmol/L vs. 145.3±131.5 pmol/L; p=0.62. CONCLUSION: Elevated BMI and IR are associated with lower

  17. Center for Rehabilitation Sciences Research

    Data.gov (United States)

    Federal Laboratory Consortium — The Center for Rehabilitation Sciences Research (CRSR) was established as a research organization to promote successful return to duty and community reintegration of...

  18. Energetics Manufacturing Technology Center (EMTC)

    Data.gov (United States)

    Federal Laboratory Consortium — The Energetics Manufacturing Technology Center (EMTC), established in 1994 by the Office of Naval Research (ONR) Manufacturing Technology (ManTech) Program, is Navy...

  19. Center for Neuroscience & Regenerative Medicine

    Data.gov (United States)

    Federal Laboratory Consortium — The Center for Neuroscience and Regenerative Medicine (CNRM) was established as a collaborative intramural federal program involving the U.S. Department of Defense...

  20. Blood lead levels in preschool children in Cape Town

    Energy Technology Data Exchange (ETDEWEB)

    Deveaux, P.; Kibel, M.A.; Dempster, W.S.; Pocock, F.; Formenti, K.

    1986-03-29

    Blood lead levels were assessed in 293 children aged between 4 and 6 years attending preschool centers in metropolitan Cape Town in order to establish the degree of lead absorption. Anthropometric data, blood count, zinc protoporphyrin and blood lead level were obtained for each child. A questionnaire was used to determine socio-economic status, dietary habits and history of pica. Thirteen children, or 4,4% of those sampled, had blood levels of greater than or equal to 30 micrograms/dl. The majority of these children lived in close proximity to one another in a socially deprived inner urban environment. Environmental sampling for lead was carried out in the homes of children with the highest blood levels as well as in the homes of a matched control group with low levels living in the same area. The only difference was a significantly higher incidence of pica in the children with high levels.

  1. Evaluation of the Five Permanent Members in the Blood Purification Center Nursing Management%五常法在血液净化中心护理管理中的应用评价

    Institute of Scientific and Technical Information of China (English)

    齐娟

    2016-01-01

    目的:研究并探讨在血液净化中心的护理管理中采取五常法的应用效果。方法于2014年1月开始,该院血液净化中心护理管理中开始实施五常法管理,对2014年1月—2015年12月(观察阶段)实施五常法管理后的透析用水卫生质量进行监测;另对2012年1月—2013年12月(对照阶段)未实施五常法管理时的透析用水质量进行监测,了解工作人员的满意度和幸福指数。结果与对照阶段相比,观察阶段的透析用水卫生质量合格率达到100%,质量控制效果明显更好(P<0.05),透析用水内毒素、透析用水菌落数、透析用水污染物、透析用水有机氯均未出现超标情况。在满意度和幸福指数方面,实施五常法管理后的观察阶段工作人员的满意度和幸福指数均得到有效提高(P<0.05)。结论在血液净化中心的护理管理中,采用五常法进行管理可有效改善血液净化中心的透析用水卫生质量,提高工作人员的满意度。%Objective To study and explore the application effect of 5S management of nursing management in the blood purification center. Methods Beginning in January 2014, the blood purification center nursing management of our hospital began to implement the 5S management, in January 2014 ~December 2015 (observation phase), the hemodialysis water san_itary quality of 5S management implementation was monitored; Another from January 2012 to December 2013 (control phase) without the implementation of 5S management, the hemodialysis water quality was monitored, and the staff's satisfac_tion and happiness index were investigated. Results Compared with the control phase , the dialysis water sanitation quality pass rate of the observed phase was 100%, quality control effect was better (P<0.05), dialysis water for endotoxin, dialysis water colony number, dialysis water pollutants, dialysis water organic chlorine had not now exceeded. In terms of satisfaction and happiness

  2. Diagnóstico del Síndrome de Burnout en trabajadores del Centro de Inmunología y Biopreparados Diagnostic of burnout Syndrome in Workers at inmunology and blood by products center

    Directory of Open Access Journals (Sweden)

    Yury Rosales Ricardo

    2011-12-01

    Full Text Available Se realizó un estudio transversal entre marzo y abril de 2011 con 40 trabajadores del Centro de Inmunología y Biopreparados de Holguín a los cuales se les aplicó la encuesta de Maslach Burnout Inventory con el objetivo de diagnosticar el Síndrome de Burnout en esta población. De la muestra analizada, ocho trabajadores fueron diagnosticados con Síndrome de Burnout, de estos, cuatro con una evaluación de medio y cuatro con alto, representando el 20% del total. El Síndrome de Burnout fue más frecuente en mujeres, trabajadoras de oficina de nivel superior y medio superior entre los 26 y los 52 años de edad. La aplicación de la herramienta de Maslach permitió diagnosticar el Síndrome de Burnout en los trabajadores de esta entidad entre trabajador de oficina y de producción y servirá como base para la toma de decisiones administrativas en aras de mejorar la calidad del principal recurso de una empresa: el hombre.A transversal study was carried out between March and April 2011, with 40 workers of the Immunology and Blood Products Center in Holguín, to whom we applied the Maslach Burnout Inventory Test to determinate Burnout Syndrome. Eight of these workers were diagnosed with Burnout Syndrome, 4 of which had a medium evaluation and 4 which had a high evaluation, representing 20% of the total. Women had more Burnout Syndrome than men and were office workers with medium-high school, between 26 and 52 years old. The application of this test allowed us to diagnose the Burnout Syndrome in office and production workers of the Immunology and Blood Products Center in Holguin. This tool will be useful in management decisions to improve the quality of life the company's main resource: the human being.

  3. Sickle cell disease and pregnancy: analysis of 34 patients followed at the Regional Blood Center of Ribeirão Preto, Brazil

    Directory of Open Access Journals (Sweden)

    Ana Cristina Silva-Pinto

    2014-10-01

    Full Text Available Objective: The objective of this study was to verify the evolution of pregnancies in sickle cell patients followed at one institution over a period of 12 years (January 2000 to June 2012. Methods: The study evaluated 34 pregnant women with sickle cell disease with a mean age of 23.9 ± 5.3 years. The incidence of obstetric complications, non-obstetric complications linked to sickle cell disease and complications in the newborn were analyzed. Results: A total of 26% of the cases reported previous miscarriages, 20% had preterm labor, 10% had pre-eclampsia, and 5% had gestational diabetes. Forty-one percent of the deliveries were cesarean sections and 29% of patients required blood transfusions. In respect to sickle cell disease, 62% of patients had vaso-occlusive crises, 29% had acute chest syndrome, 23% had urinary tract infection, 15% had impaired cardiac function and 6% developed pulmonary hypertension. Only one patient died in the postnatal period due to acute chest syndrome. The mean gestational age was 37.8 ± 2.63 weeks, and mean newborn weight was 2.809 ± 643.8 g. There were seven fetal losses, including three stillbirths and four miscarriages. The impact of transfusion therapy on the incidence of maternal–fetal complications during pregnancy was evaluated. Conclusions: Pregnancy in sickle cell patients is still associated with complications. Although no statistical difference was observed between transfused and non-transfused women, there were no deaths (fetal or maternal in transfused patients whereas one maternal death and three stillbirths occurred in non-transfused women. A larger study of sickle cell pregnant women will be necessary to elucidate the actual role of transfusion during pregnancy in sickle cell disease.

  4. Money for Blood and Markets for Blood.

    Science.gov (United States)

    Derpmann, Simon; Quante, Michael

    2015-12-01

    Ontario's Bill 178 proposing a Voluntary Blood Donations Act declares the offer or acceptance of payment for the donation of blood a legal offence and makes it subject to penalty. The bill reinvigorates a fundamental debate about the ethical problems associated with the payment of money for blood. Scarcity of blood donors is a recurring problem in most health systems, and monetary remuneration of the willingness to donate blood is regularly discussed--and sometimes practiced--as a means to overcome scarcity in blood. However, making blood an object of economic exchange has long aroused ethical concerns that often refer to the specific meaning of blood. From the perspective of a modern understanding of money as a metric of economic value, the exchange of money for blood--shed or given--is seen as ethically troubling, because it appears to imply a commensurability of the value of human life and economic wealth. In this paper, we begin with a general taxonomy of the types of arguments that speak in favour or against compensating donors for giving blood. We then describe the context in which the discussion about payment for blood arises, and of the specific aims and concerns that are brought forward in this context. This is used to reconstruct the normative background that supports the rejection of payment for blood as it is envisaged in Bill 178 and the aims of the proposal. We then argue that while a payment indeed changes the nature of a blood donation in an ethically considerable way, we do not believe that decisive arguments against the monetary remuneration of blood donations can be substantiated, at least not independently of assuming specific societal circumstances. Thus it may be possible to establish a stable and safe blood supply through just gratification while at the same time taking strong provisions against social disconnection, injustice, exploitation or heteronomy.

  5. American Alligator Research on the Kennedy Space Center

    Science.gov (United States)

    Lowers, Russell H.

    2010-01-01

    This slide presentation reviews the research conducted at the Kennedy Space Center on the American Alligator. The objectives of the research were to establish life history baseline at the Kennedy Space Center and at the Merit Island National Wildlife Reserve (MINWR). Some of the factors that were examined are: nesting success, movement patterns, and population structure. Another objective was to determine the overall health of the alligator population, by analyzing blood and tissue chemistry, and urine analysis. A third objective was to compare alligators at KSC/MINWR to the statewide population. Some of the results are shown in charts and graphs.

  6. Blood smear

    Science.gov (United States)

    ... some red blood cells shaped like spheres ( hereditary spherocytosis ) Increased breakdown of RBCs Presence of RBCs with ... normal Red blood cells, elliptocytosis Red blood cells, spherocytosis Acute lymphocytic leukemia - photomicrograph Red blood cells, multiple ...

  7. Blood culture

    Science.gov (United States)

    Culture - blood ... A blood sample is needed . The site where blood will be drawn is first cleaned with an antiseptic such ... organism from the skin getting into (contaminating) the blood sample and causing a false-positive result (see ...

  8. Blood Thinners

    Science.gov (United States)

    If you have some kinds of heart or blood vessel disease, or if you have poor blood flow to your brain, your doctor may recommend that you take a blood thinner. Blood thinners reduce the risk of heart ...

  9. Blood transfusions

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/patientinstructions/000431.htm Blood transfusions To use the sharing features on this ... several sources of blood which are described below. Blood From the Public (Volunteer Blood Donation) The most ...

  10. CURRICULUM GUIDE, CHILD CARE CENTERS.

    Science.gov (United States)

    California State Dept. of Education, Sacramento.

    CALIFORNIA CHILD CARE CENTERS WERE ESTABLISHED IN 1943 TO SUPPLY SERVICES TO CHILDREN OF WORKING MOTHERS. THE CHILD CARE PROGRAM PROVIDES, WITHIN NURSERY AND SCHOOLAGE CENTERS, CARE AND EDUCATIONAL SUPERVISION FOR PRESCHOOL AND ELEMENTARY SCHOOL AGE CHILDREN. THE PHILOSOPHY OF THE CHILD CENTER PROGRAM IS BASED UPON THE BELIEF THAT EACH CHILD…

  11. Application of the Informatization Management System in Nursing Error Prevention in the Blood Puriifcation Center%信息化管理系统在防范血净中心护理差错中的应用

    Institute of Scientific and Technical Information of China (English)

    汪静美; 王云燕

    2015-01-01

    目的:探讨血净中心应用信息化管理系统在防范护理差错中的效果。方法选取80例维持性血液透析患者进行调查。采用自身对照,80名患者2013年6~9月(对照组)采用传统的医疗实施和管理行血液透析(HD)共1953台次,血液透析滤过(HDF)共910台次;2013年10~12月(实验组)采用信息化管理系统行HD共1923台次,HDF共903台次。回顾分析两组护理差错的发生概率,并采用卡方(χ2)检验。结果对照组护理差错发生33例,所占比例为1.15%;而实验组为4例,所占比例为0.14%。对比两组结果,口头医嘱执行错误、回路管固定不当和治疗模式错误发生率具有显著性差异(P<0.05)。结论信息化管理系统有利于血净中心护理差错的防范。%Objective To investigate the application effectiveness of the informatization management system in nursing error prevention in the blood purification center.Methods Altogether 80 MHD (Maintenance Hemo-Dialysis) patients were selected. Taking themselves as the reference, 80 MHD patients (The Control Group) had accepted a total of 1953 times of HD treatment and 910 times of HDF (Hemo-Dia-Filtration) treatment in the blood puriifcation center from June to September 2013 under the traditional medical implementation and management mode. With the application of the informatization management system in medical implementation and management, all the 80 patients (The Experimental Group) undergone 1923 times of HD treatment and 903 times of HDF treatment from October to December 2013. Then, retrospective analysis was made between two groups in the occurrence rate of nursing errors. And the chi-square test was used.Results A total of 33 nursing errors happened in Control Group (Accounting for 1.15%); while, only 4 cases of nursing errors occurred in Experimental Group (0.14%). In comparison between the results of two groups, significant differences (P<0.05) existed in

  12. Toward a patient-based paradigm for blood transfusion

    Directory of Open Access Journals (Sweden)

    Farrugia A

    2014-01-01

    Full Text Available Albert Farrugia,1,2 Eleftherios Vamvakas31College of Medicine, Biology and Environment, Australian National University, Acton, ACT, Australia; 2Centre for Orthopaedic Research, Department of Surgery, Faculty of Medicine and Surgery, University of Western Australia, Perth, WA, Australia; 3Cedars-Sinai Medical Center, Los Angeles, CA, USAAbstract: The current "manufacturing paradigm" of transfusion practice has detached transfusion from the clinical environment. As an example, fresh whole blood in large-volume hemorrhage may be superior to whole blood reconstituted from multiple components. Multicomponent apheresis can overcome logistical difficulties in matching patient needs with fresh component availability and can deliver the benefits of fresh whole blood. Because of the different transfusion needs of patients in emerging economies and the vulnerability of these blood systems to emerging infections, fresh whole blood and multicomponent apheresis can better meet patient needs when compared with transplants of the "manufacturing paradigm". We propose that patient blood management, along with panels of repeat, paid, accredited apheresis and fresh whole-blood donors can be used in emerging economies to support decentralized blood services. This alternative transfusion–medicine paradigm could eventually also be adopted by established economies to focus transfusion medicine on local patient needs and to alleviate the problem of the aging volunteer donor base.Keywords: indications, emerging countries, patient blood management

  13. The effect of application of Quality care in the blood purification center%优质护理在血液净化中心的应用效果分析

    Institute of Scientific and Technical Information of China (English)

    陈远文; 曾建芬; 周兰芬

    2014-01-01

    目的:探究优质护理在血液净化中心的应用效果分析。方法:选取血液净化患者100例。将100例患者随机分为采用常规护理的对照组,以及采用优质护理的观察组,每组50例患者。对两组患者进行护理干预后的急诊透析次数、满意度以及并发症情况进行比较分析。结果:采用优质护理的观察组的平均急诊透析次数和并发症明显少于对照组;患者满意度明显优于对照组。差异均具有统计学意义(P <0.05)。结论:对血液净化患者采用优质护理模式可以明显地减少急诊透析次数,大大降低并发症的发生率,从而提升患者的满意度,临床上值得推广应用。%Objective To investigate the effect of high - quality care in the application of the analysis of blood purification cen-ter. Method 100 patients were treated for blood purification and randomly divided into a control group with conventional treatments,and the use of high - quality care in the observation group,50 patients in each group. The number of emergency dialysis care for two groups of patients after the intervention,satisfaction and complications were analyzed. Results The quality of care in the observation group and the mean number of emergency dialysis complications was significantly less than the control group;patient satisfaction was significantly better than the control group. The differences were statistically significant(P < 0. 05). Conclusion Patients with blood purification using high -quality model of care can significantly reduce the number of emergency dialysis,greatly reduce the incidence of complications,thereby en-hancing patient satisfaction,should be widely applied clinically.

  14. 创建一流临床技能中心培养创新型医学人才%Establishment of clinical skills center for training the creative ability of medical students

    Institute of Scientific and Technical Information of China (English)

    许杰州; 施楚君; 吴丽萍; 吴凡; 杨棉华; 黄东阳

    2008-01-01

    通过临床技能教学改革,达到培养创新型医学人才的目的 .汕头大学医学院通过更新教学理念,改革课程体系,建立多功能、全方位的临床技能中心等方法 ,培养既有扎实理论知识又有娴熟临床技能与思维能力的创新型医学人才.经过5年的实践,学生不但在专业知识、人文素质、临床技能水平、创新能力培养等方面取得了可喜的效果,而且得到了社会的良好评价和认可.%The objective of the study is to reform clinical skills education in order to develop creative ability of medical students. Update the education idea, reform the teaching program and set up an excellent clinical skills training center in order to develop creative ability of medical students who are good at clinical skills, critical clinical thinking and consolidated medical knowledge following 5 years practice. The students were obviously promoted in many aspects, including professional knowledge, quality of humanity, clinical skills and creative ability.

  15. Excel Center

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Citigroup,one of the World top 500 companies,has now settled in Excel Center,Financial Street. The opening ceremony of Excel Center and the entry ceremony of Citigroup in the center were held on March 31.Government leaders of Xicheng District,the Excel CEO and the heads of Asia-Pacific Region leaders of Citibank all participated in the ceremony.

  16. Bacteriological Controls at Czechoslovakia Blood Transfusion Centers.

    Science.gov (United States)

    1961-07-01

    originator of the impurity (chemi- cals, water, air , poor work habits). Results The extent of the bacteriological control carried cit in our station...and its results are summarized in Table 1. which also gives the percentage of the incidence of bacterial contaminacion of the various kinds of

  17. Blood Donation

    Science.gov (United States)

    Tests and Procedures Blood donation By Mayo Clinic Staff Blood donation is a voluntary procedure. You agree to have blood drawn so that it can ... have a disease that requires blood components. Blood donation makes all of this possible. There are several ...

  18. PDCA循环法在血液净化中心应急预案演练中的应用%Application in Emergency Training Plan of Blood Purification Center by PDCA Cycle Method

    Institute of Scientific and Technical Information of China (English)

    孙敏

    2016-01-01

    目的:通过PDCA循环法在血液净化中心突发事件应急预案演练中的应用,提高了血液净化护士的应急能力。方法运用PDCA循环法,先拟定突发事件应急预案演练内容,如:医院感染暴发、透析中的低血压、透析器破膜、透析期间的突然停电、停水、火警、地震等。然后实施"执行、检查、处理"等循环管理方式,不断完善措施补充到新的应急预案流程中。通过一次次的PDCA循环,使存在的问题得以改进,直到护士能够熟练掌握该项应急流程为止。结果演练开始前及演练结束后,立即对参与演练及观摩人员进行应急流程理论测试及应急相关的操作考核。结果显示,演练前后护士的应急流程理论及操作考核成绩比较差异均有统计学意义(<0.01)。结论将PDCA循环法应用于血液净化中心的应急预案演练中,体现质量持续改进,提高了护士综合能力及应急反应能力.对突发事件应急流程的掌握及相关急救操作能力也明显提高。%Objective To purify the application of emergency events in blood purification center by PDCA cycle, improve the ability of emergency nurses in blood purification. Methods Using PDCA method, first developed emergency preparedness training emergency, such as: the outbreak of nosocomial infection in hemodialysis, hypotension during dialysis, dialysis membrane rupture, sudden blackouts, water, fire, earthquake, etc. Then the implementation of the :do,check,act recyclingmanagement mode, continuous improvement measures to supplement to process emergency plan in the new. Through a PDCA loop, so that the problems can be improved, until the nurse can master the emergency procedure. Results The exercise before and after the drill, drill and observers immediately to participate in emergency process theory test and emergency related operation assessment. The results show, practice nurses before and after the emergency

  19. Establishment and Application of Quality Control Traceability System in Sterilization Supply Center%消毒供应中心质量控制可追溯系统的构建与应用

    Institute of Scientific and Technical Information of China (English)

    何晓滨; 樊彦红

    2013-01-01

      目的:探讨医院中建立消毒供应中心质量控制可追溯系统的临床价值。方法:利用信息技术、网络技术,研发了信息化条码标签,将信息系统与消毒灭菌生产供应链管理有效结合,建立了质量控制可追溯软件系统,实现消毒供应器械物品监控。结果:2011年7月至2012年12月共扫描供应监控手术器械包667735个,敷料包53520个,合格率为100%,无因灭菌质量问题引发感染事故发生。结论:质量控制可追溯软件系统加强了消毒灭菌生产供应链管理过程控制,保障了消毒供应产品质量和医疗安全,实现了感染控制的追溯管理,为临床和科学研究提供方便,具有实用价值。%Objective: To discuss clinic value how to establish the central sterile supply quality control traceability system in the military hospitals. Methods: The informatization bar code label was developed independently by adopting Information technology, network technology, the central sterile supply quality control traceability system was established through scanning, combine effectively the information system with the disinfection antiseptic production supplying chain management, and the scanning supply monitoring was performed for the disinfection and supply of instruments and materials. Results:From July 2011 to Dec 2012, the scanning supply monitoring was performed for to tally 667735 surgery instrument packages and 53520 cloth packages no package recalled and no infection events occurred due to the sterilization quality. Conclusions With the central sterile supply quality control traceability system, the process of disinfection antiseptic production supply chain management has been strengthened, the quality of disinfection supply product and medical security have been ensured, and the traceability management of infection control has been achieved, provide conditions for clinical and scientific research.

  20. Donating Blood

    Science.gov (United States)

    ... can't get an infection or disease from giving blood. The needles and other equipment used are sterile ... part of blood (plasma) within 72 hours after giving blood. It generally takes about 4–8 weeks to ...

  1. Red blood cells, spherocytosis (image)

    Science.gov (United States)

    Spherocytosis is a hereditary disorder of the red blood cells (RBCs), which may be associated with a mild anemia. Typically, the affected RBCs are small, spherically shaped, and lack the light centers seen ...

  2. The heritability of blood donation

    DEFF Research Database (Denmark)

    Pedersen, Ole Birger; Axel, Skytthe; Rostgaard, Klaus

    2015-01-01

    BACKGROUND: Voluntary blood donation is believed to be mostly motivated by altruism. Because studies have suggested that altruistic personality is determined by both genetic and environmental factors, we speculated that willingness to donate blood could also be governed by constitutional factors...... active Danish blood donors from 2002 to 2012, to establish blood donor status for Danish twins, who at age 17 years became eligible for donation in 2002 or later. Casewise concordance in monozygotic (MZ) and dizygotic (DZ) twins were presented and heritability was estimated in Mx by variance component...... to donate blood, respectively. CONCLUSION: Becoming a volunteer blood donor is determined by both genetic and environmental factors shared within families....

  3. Freqüência de hemolisinas anti-A e anti-B em doadores de sangue do Hemocentro de Botucatu Anti-A and anti-B hemolysin frequencies in blood donors from the Hemotherapy Center of Unesp, Botucatu

    Directory of Open Access Journals (Sweden)

    Sheley Gambero

    2004-03-01

    antibodies are found in the serum of individuals, and are directed against the A and B antigens absent in the red cells. Although transfusions with low quantities of incompatible plasma are generally considered a safe practice, some cases of hemolytic reactions owing to incompatible plasma are described in the literature. Despite the lack of information about anti-A and anti-B hemolysins and the importance of this antibody in transfusional practice, we proposed in this work to investigate the frequencies of these hemolysins in blood donors from de Hemotherapy Center of Unesp Botucatu. Six hundred samples of blood sera from voluntary donors of the "O" blood group were analyzed to test for the presence or absence of anti-A and anti-B hemolysins. A total of 77 (12.8% of the donors were classified as high-risk donors with the presence of high serum levels of hemolysins and 523 (87.2% were classified as safe, presenting with low levels of hemolysins. In the group of high-risk donors, 45 (58.4% reacted with anti-A hemolysin, 11 (14.2% reacted with anti-B hemolysin and 21 (27.2% reacted with both of the hemolysins. Donors with a hemolysin level of over 1/100 were considered as high-risk "O" donors. The tests performed in our daily routine is enough to detect high levels thereby avoiding the risk of other blood group patients having transfusional reactions when there is a need of receiving blood transfusions from other blood group donors.

  4. Analytical model for calculating indeterminate results interval of screening tests, the effect on seroconversion window period: a brief evaluation of the impact of uncertain results on the blood establishment budget.

    Science.gov (United States)

    Pereira, Paulo; Westgard, James O; Encarnação, Pedro; Seghatchian, Jerard

    2014-10-01

    The evaluation of measurement uncertainty is not required by the European Union regulation or blood establishments’ laboratory tests. However, it is required for tests accredited by ISO 15189. Also, the forthcoming ISO 9001 edition requires “risk based thinking” with risk described as “the effect of uncertainty on an expected result”. ISO recommends GUM models for determination of measurement uncertainty, but their application is not intended for ordinal value measurements, such as what happens with screening test binary results. This article reviews, discusses and proposes concepts intended for measurement uncertainty of screening test results. The precision model focuses on cutoff level allowing the evaluation of the indeterminate interval using analytical sources of variance. The intervalis considered in the estimation of the seroconversion window period. The delta-value of patients and healthy subjects’ samples allows ranking two tests according to the probability of the two classes of indeterminate results: chance of false negative results and chance of false positive results (waste on budget).

  5. On the Urgency and the Principles of Constructing Center for Faculty & Teaching Development in Newly-established Universities%新建本科院校教师教学发展中心建设的迫切性和原则∗

    Institute of Scientific and Technical Information of China (English)

    胡建新; 王工一

    2015-01-01

    教学发展是高校教师发展的核心和基础,国家已将高校教师教学发展中心建设作为高校内涵发展的重要举措之一。新建本科院校的“新建性”决定了其建设教学发展中心、推动教师教学发展的迫切性。建设教师教学发展中心需遵循教学学术性原则、实践性原则、研究性原则、服务性原则和健全性原则。%Teaching development is the core of the faculty development and the central government has made the construction of the center for teaching development of university teachers one of the critical measures in developing the connotation of colleges and universities. It is urgent for newly-established universities to build the center for faculty and teaching development and promote the teaching abilities of teachers. The con-struction of the center for teaching development should abide by such principles as being academic in teach-ing, being feasible, being research-oriented, being service-oriented, and being integrated.

  6. Distribution center

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    Distribution center is a logistics link fulfill physical distribution as its main functionGenerally speaking, it's a large and hiahly automated center destined to receive goods from various plants and suppliers,take orders,fill them efficiently,and deliver goods to customers as quickly as possible.

  7. NMA Analysis Center

    Science.gov (United States)

    Kierulf, Halfdan Pascal; Andersen, Per Helge

    2013-01-01

    The Norwegian Mapping Authority (NMA) has during the last few years had a close cooperation with Norwegian Defence Research Establishment (FFI) in the analysis of space geodetic data using the GEOSAT software. In 2012 NMA has taken over the full responsibility for the GEOSAT software. This implies that FFI stopped being an IVS Associate Analysis Center in 2012. NMA has been an IVS Associate Analysis Center since 28 October 2010. NMA's contributions to the IVS as an Analysis Centers focus primarily on routine production of session-by-session unconstrained and consistent normal equations by GEOSAT as input to the IVS combined solution. After the recent improvements, we expect that VLBI results produced with GEOSAT will be consistent with results from the other VLBI Analysis Centers to a satisfactory level.

  8. Development of outsourcing higher educational establishment marketable business system

    Directory of Open Access Journals (Sweden)

    Darya A. Pushkareva

    2011-04-01

    Full Text Available The article considers outsourcing technique implementation in Higher Educational Establishment activity. Outsourcing allows to simplify organization structure, improve management and center on primary activity.

  9. The Bombay blood group: are we out of risk?

    Science.gov (United States)

    Dipta, T F; Hossain, A Z

    2011-07-01

    The Bombay blood group is a rare blood group, phenotypes of this group lacking H antigen on the red cell membrane and have anti-H in the serum. It fails to express any A, B or H antigen on their red cells or other tissues. The existence of a human H/h genetic polymorphism was first established by Bhende et al. As first discovery in Bombay (Mumbai), in India in 1952, so the name of this rare blood group is known as Bombay blood group. People having Bombay phenotype are mostly confined to the Southeast Asia. Around 179 persons in India with a frequency of 1 in 10,000 have "Bombay Blood group". A high level of consanguinity present among the parents of the Bombay phenotype. The classic Bombay phenotype has been reported in those of Indian descendent. It is quite rare in Caucasian with an incidence of 1 in 250,000. As because in our country there is routine practice of "only forward or cell type grouping" using finger prick method by voluntary blood donors organization and various blood banks; so there is tremendous chance of misinterpretation or unexploration of this Bombay blood group. When misdiagnosed, this Bombay group can cause fatal haemolytic transfusion reaction. For this reason our suggestion is to incorporate "routine serum typing or reverse grouping confirmation" along with 'O' cell control in reverse grouping procedure in every Transfusion Medicine Department or Blood Bank or Blood Donor Centers and this practice should be mandatory to reduce the risk of fatal haemolytic transfusion reaction. In this view we will highlight the incidence, molecular biology and clinical significance of this rare and fatal blood group.

  10. Marcadores sorológicos das hepatites B e C em doadores de sangue do Hemocentro de Ribeirão Preto, SP Hepatitis B and C serologic markers in blood donors of the Ribeirão Preto Blood Center

    Directory of Open Access Journals (Sweden)

    Vanderléia Bárbaro Valente

    2005-12-01

    Full Text Available Este estudo envolveu 25.891 doadores de sangue que compareceram pela primeira vez ao Hemocentro de Ribeirão Preto, entre 23/06/1996 e 22/06/2001. Seu objetivo foi estudar a positividade de marcadores sorológicos das hepatites B e C em testes de triagem e estimar a prevalência de infecção atual ou pregressa pelos vírus de ambas as hepatites, através da análise dos resultados de testes confirmatórios. Estudaram-se dados do Hemocentro e do Hospital das Clínicas da Faculdade de Medicina, coletando-se informações referentes ao doador e aos resultados dos testes sorológicos. A população foi composta majoritariamente por homens (83,6% de 26 a 45 (64% anos de idade. Os valores de positividade nos testes da triagem foram 0,6% (IC95%: 0,54 0,72 para o HBsAg e 1,2% (IC95%: 1,02 1,28, para o anti-HCV. Os valores da prevalência, nos testes confirmatórios, foram 0,2% (IC95%: 0,16 0,28, para a hepatite B, e 0,3% (IC95%: 0,24 0,38 para a hepatite C.The investigation involved 25,891 blood donors who attended for the first time the Blood Center of Ribeirão Preto, Brazil, between Jun 23, 1996 and Jun 22, 2001. The objective was to study the proportion of positive serological markers for hepatitis B and C at the initial screening tests and to estimate the prevalence of such infections through the analysis of confirmatory tests, carried out at the University Hospital as a part of the patients evaluation. Data from the donors and laboratory results were obtained from the records of both the Blood Bank and the Hospital. The population of donors was mainly composed by males (83.6% and by individuals between 26 and 45 (64% years of age. The proportions of positive results in screening tests were 0.6% (CI95%: 0.54 0.72 for HBsAg and 1.2% (CI95%: 1.02 1.28 for anti-HCV. Confirmatory testes showed values of prevalence of 0.2% (CI95%: 0.16 0.28 for hepatitis B and 0.3% (IC95%: 0.24 0.38 for hepatitis C.

  11. Transportation Research & Analysis Computing Center

    Data.gov (United States)

    Federal Laboratory Consortium — The technical objectives of the TRACC project included the establishment of a high performance computing center for use by USDOT research teams, including those from...

  12. Artificial blood

    Directory of Open Access Journals (Sweden)

    Sarkar Suman

    2008-01-01

    Full Text Available Artificial blood is a product made to act as a substitute for red blood cells. While true blood serves many different functions, artificial blood is designed for the sole purpose of transporting oxygen and carbon dioxide throughout the body. Depending on the type of artificial blood, it can be produced in different ways using synthetic production, chemical isolation, or recombinant biochemical technology. Development of the first blood substitutes dates back to the early 1600s, and the search for the ideal blood substitute continues. Various manufacturers have products in clinical trials; however, no truly safe and effective artificial blood product is currently marketed. It is anticipated that when an artificial blood product is available, it will have annual sales of over $7.6 billion in the United States alone.

  13. Artificial blood.

    Science.gov (United States)

    Sarkar, Suman

    2008-07-01

    Artificial blood is a product made to act as a substitute for red blood cells. While true blood serves many different functions, artificial blood is designed for the sole purpose of transporting oxygen and carbon dioxide throughout the body. Depending on the type of artificial blood, it can be produced in different ways using synthetic production, chemical isolation, or recombinant biochemical technology. Development of the first blood substitutes dates back to the early 1600s, and the search for the ideal blood substitute continues. Various manufacturers have products in clinical trials; however, no truly safe and effective artificial blood product is currently marketed. It is anticipated that when an artificial blood product is available, it will have annual sales of over $7.6 billion in the United States alone.

  14. "Infotonics Technology Center"

    Energy Technology Data Exchange (ETDEWEB)

    Fritzemeier, L. [Infotonics Technology Center Inc., Canandaigua, NY (United States); Boysel, M. B. [Infotonics Technology Center Inc., Canandaigua, NY (United States); Smith, D. R. [Infotonics Technology Center Inc., Canandaigua, NY (United States)

    2004-09-30

    During this grant period July 15, 2002 thru September 30, 2004, the Infotonics Technology Center developed the critical infrastructure and technical expertise necessary to accelerate the development of sensors, alternative lighting and power sources, and other specific subtopics of interest to Department of Energy. Infotonics fosters collaboration among industry, universities and government and operates as a national center of excellence to drive photonics and microsystems development and commercialization. A main goal of the Center is to establish a unique, world-class research and development facility. A state-of-the-art microsystems prototype and pilot fabrication facility was established to enable rapid commercialization of new products of particular interest to DOE. The Center has three primary areas of photonics and microsystems competency: device research and engineering, packaging and assembly, and prototype and pilot-scale fabrication. Center activities focused on next generation optical communication networks, advanced imaging and information sensors and systems, micro-fluidic systems, assembly and packaging technologies, and biochemical sensors. With targeted research programs guided by the wealth of expertise of Infotonics business and scientific staff, the fabrication and packaging facility supports and accelerates innovative technology development of special interest to DOE in support of its mission and strategic defense, energy, and science goals.

  15. Establishment of the Data and Analysis Center for Software (DACS).

    Science.gov (United States)

    1982-01-01

    This resulted in the development of a set of report generation, graphical and data analysis software packages which will be utilized to provide...synthesized biblio- Custom Searches" (1B-I) graphic database information. Produced SOA Report *Quantitative Produced SOA Report "Software Main- Produced...of high interest tu ORS tape specifications uASA-DM, Commerce Business Dally or. rio dese The data Is being collect durinng a Beta Treat al IPamsu of

  16. Center for Automation and Manufacturing Science Established at Stanford University.

    Science.gov (United States)

    1985-12-01

    C-spaces using screw theory . One of the bodies represented as a point can contact the C-space of the other body under configurations that have...assembly position. This problem has been posed as a sub-graph search problem. The essential tool to search the graph using the screw theory of ’form

  17. National Imperative to Establish a Domestic Medical Intelligence Center

    Science.gov (United States)

    2007-09-01

    Quality Reports Human and Veterinarian Health Surveillance Indicators Coordination with other TEW Cells Exploring Medical and Public Health...and territorial governments, animal shelters, the American Society for the Prevention of Cruelty to Animals, veterinarians , and other sources...General medicine/family practice 63 • Hematology • Infectious disease • Internal medicine • Nephrology • Nuclear medicine o In-vivo

  18. Center for Disaster & Humanitarian Assistance Medicine

    Data.gov (United States)

    Federal Laboratory Consortium — The Center for Disaster and Humanitarian Assistance Medicine (CDHAM) was formally established at the Uniformed Services University of the Health Sciences (USUHS) by...

  19. 8岁以下儿童末梢血血红蛋白参考范围分析%Establishment of Reference Intervals for Peripheral Blood Hemoglobin Aiming at Children below 8 Years Old

    Institute of Scientific and Technical Information of China (English)

    梁有勇

    2012-01-01

    目的 建立≤8岁儿童末梢血血红蛋白的参考范围.方法 选择2010年5月-2011年10月在我院健康体检的≤8岁儿童1 514例,按年龄分组:3~12个月组429例,1~3岁组462例,4~8岁组623例.均经体检证明生长、发育正常,无慢性病史,无血红蛋白疾病史和贫血史,无血吸虫、钩虫、疟疾等寄生虫感染的贫血,无蚕豆病.检查前未接受过铁剂和输血治疗.结果 1 514个血红蛋白测定值,偏度系数为0.401,峰度系数为-0.117,呈近似正态分布.3~12个月组、1~3岁组、4~8岁组男童、女童及男女合计血红蛋白水平比较差异均有统计学意义(P<0.05).3~12个月儿童血红蛋白参考范围为96~125 g/L,1~3岁儿童血红蛋白参考范围为100~129 g/L,4~8岁男童血红蛋白参考范围为101~137 g/L,4~8岁女童血红蛋白参考范围为103~131 g/L.结论 不同年龄段应采用不同的血红蛋白参考范围,不同实验室应建立适合自己的血红蛋白的参考范围.%Objective To determine the reference intervals for hemoglobin of peripheral blood aiming at children below 8 years old. Methods We selected 1 514 healthy children below 8, inclusive who came to our hospital for physical check -up from May 2010 to October 2011 and according to their ages divided them into three groups : 3 ~ 12 months group 429 cases, 1 ~ 3 year olds group 462 cases, 4 ~ 8 years old group 623 cases. All the subjects underwent physical examination and were con -firmed normal in their growth and development , without any chronic disease , hemoglobin disease , anemia, favism and anemia caused by schistosomiasis , hookworm, malaria and they didn 't receive iron supplements or any kind of transfusion therapy. Re-sults All subjects' hemoglobin level was approximately positively distributed with coefficient of skewness being 0. 401 and coeffi-cient of kurtosis being -0. 117. The differences between males , females, males and females together in the three

  20. Influence of empowerment management on nursing quality in blood pnrification center%授权管理对血液净化科护理质量的影响

    Institute of Scientific and Technical Information of China (English)

    胡瑞霞; 李丽梅

    2012-01-01

    目的 探讨护理风险授权管理模式在血液净化科的应用效果.方法 选择16名护理人员,将护理风险授权给6个管理小组,各组负责各自环节护理工作.授权护理风险管理实施前后分别选择在本科进行维持性血液透析治疗的患者100例,比较授权前后的护理工作效果.结果 授权管理后护理质量评分、患者满意度较授权管理前均有显著提高.结论 积极有效的护理风险授权管理,能够持续提高护士管理效能,激发护理人员工作积极性和创造力,降低护理风险发生,是全面提升护理质量的有效管理方法.%Objective To analyze the effect of empowerment management for nursing risk in blood purification center.Methods 16 nurses were chosen and nursing risk were authorized to six management groups,each group was respectively responsible for their share of nursing work.Before the implementation of empowerment management for nursing risk,100 patients undergoing maintenance hemodialysis were chosen,and after the implementation another 100 patients were also selected.The nursing effect was compared before and after the implementation.Results After the implementation,the score of nursing quality and patients' satisfaction degree were significantly improved.Conclusions The effective empowerment management for nursing risk can raise management effect of nurses continuously,and stir up the initiative and creativity of nursing staff,lower nursing risk occurrence.It is an effective management method that promotes nursing quality comprehensively.

  1. Human leukocyte antigen supertype matching after myeloablative hematopoietic cell transplantation with 7/8 matched unrelated donor allografts: a report from the Center for International Blood and Marrow Transplant Research

    Science.gov (United States)

    Lazaryan, Aleksandr; Wang, Tao; Spellman, Stephen R.; Wang, Hai-Lin; Pidala, Joseph; Nishihori, Taiga; Askar, Medhat; Olsson, Richard; Oudshoorn, Machteld; Abdel-Azim, Hisham; Yong, Agnes; Gandhi, Manish; Dandoy, Christopher; Savani, Bipin; Hale, Gregory; Page, Kristin; Bitan, Menachem; Reshef, Ran; Drobyski, William; Marsh, Steven GE; Schultz, Kirk; Müller, Carlheinz R.; Fernandez-Viña, Marcelo A.; Verneris, Michael R.; Horowitz, Mary M.; Arora, Mukta; Weisdorf, Daniel J.; Lee, Stephanie J.

    2016-01-01

    The diversity of the human leukocyte antigen (HLA) class I and II alleles can be simplified by consolidating them into fewer supertypes based on functional or predicted structural similarities in epitope-binding grooves of HLA molecules. We studied the impact of matched and mismatched HLA-A (265 versus 429), -B (230 versus 92), -C (365 versus 349), and -DRB1 (153 versus 51) supertypes on clinical outcomes of 1934 patients with acute leukemias or myelodysplasia/myeloproliferative disorders. All patients were reported to the Center for International Blood and Marrow Transplant Research following single-allele mismatched unrelated donor myeloablative conditioning hematopoietic cell transplantation. Single mismatched alleles were categorized into six HLA-A (A01, A01A03, A01A24, A02, A03, A24), six HLA-B (B07, B08, B27, B44, B58, B62), two HLA-C (C1, C2), and five HLA-DRB1 (DR1, DR3, DR4, DR5, DR9) supertypes. Supertype B mismatch was associated with increased risk of grade II–IV acute graft-versus-host disease (hazard ratio =1.78, P=0.0025) compared to supertype B match. Supertype B07-B44 mismatch was associated with a higher incidence of both grade II–IV (hazard ratio=3.11, P=0.002) and III–IV (hazard ratio=3.15, P=0.01) acute graft-versus-host disease. No significant associations were detected between supertype-matched versus -mismatched groups at other HLA loci. These data suggest that avoiding HLA-B supertype mismatches can mitigate the risk of grade II–IV acute graft-versus-host disease in 7/8-mismatched unrelated donor hematopoietic cell transplantation when multiple HLA-B supertype-matched donors are available. Future studies are needed to define the mechanisms by which supertype mismatching affects outcomes after alternative donor hematopoietic cell transplantation. PMID:27247320

  2. 呼和浩特地区 RhD 阴性献血者表型库的建立及应用%Establishment and application of the phenotype database of negative RhD blood donors in Hohhot

    Institute of Scientific and Technical Information of China (English)

    尚锦青; 贾雯婷; 苏仁娜; 崔丽敏

    2015-01-01

    Objective To understand the phenotype distribution of negative RhD blood donors in local region ,and to establish negative RhD phenotype database .Methods A total of 554 specimens screened firstly as negative RhD were confirmed by indirect antiglobulin test .Repeat donors were excluded ,the remaining specimens were 366 cases ,which were analyzed the phenotype of Rh blood .Results Distribution characteristics of negative RhD phenotype was ccdee (56 .28% ) > Ccdee (29 .51% ) > ccdEe (7 .38% )> CcdEe (3 .55% )> CCdee (3 .01% )> ccdEE (0 .27% ) ,there were no CcdEE ,CCdEe ,CCdEE detected .Conclusion The establishment of Negative RhD phenotype database is help for providing matching blood for persons with negative RhD blood or same antibody blood ,and meeting the emergency blood usage ,it′s important for scientific management and reasonable application of negative RhD blood ,and accumulate data for then negative RhD blood of the local area ,especially for Mongolian .%目的:了解该地区 RhD 阴性献血者表型分布,建立 RhD 阴性表型数据库。方法 RhD 初筛阴性的554份标本采用间接抗球蛋白试验确认。排除重复献血者后,剩余标本为366份,对其进行 Rh 血型表型分析。结果 RhD 阴性表型分布特征为ccdee(56.28%)> Ccdee (29.51%)> ccdEe (7.38%)> CcdEe (3.55%)> CCdee (3.01%)> ccdEE (0.27%),未检出 CcdEE 、CCdEe 、CCdEE 型。结论建立 RhD 阴性表型数据库,有利于为 RhD 阴性及含有 Rh 同种抗体的患者提供相匹配血液,满足其急救用血,且对科学管理 RhD 阴性血源和合理运用 RhD 阴性血液有重要意义,为该地区尤其蒙古族 RhD 阴性血型积累了资料。

  3. Blood Clots

    Science.gov (United States)

    ... or prevent blood clots from dissolving properly. Risk factors for excessive blood clotting include Certain genetic disorders Atherosclerosis Diabetes Atrial fibrillation Overweight, obesity, and metabolic syndrome Some medicines Smoking deep vein ...

  4. Declínio da prevalência do HTLV-1/2 em doadores de sangue do Hemocentro Regional da Cidade de Uberaba, Estado de Minas Gerais, 1995 a 2008 Decline in the prevalence of HTLV-1/2 among blood donors at the Regional Blood Center of the City of Uberaba, State of Minas Gerais, from 1995 to 2008

    Directory of Open Access Journals (Sweden)

    Guilherme Manso de Lima

    2010-08-01

    Full Text Available INTRODUCÃO: Estudo retrospectivo com o objetivo de avaliar a prevalência e fatores associados à soropositividade para o HTLV-1/2, no período de 1995 a 2008, no Hemocentro Regional de Uberaba e descrever os doadores soropositivos quanto ao gênero, idade, estado civil, cor de pele e procedência. MÉTODOS: Foram realizados análise estatística descritiva, testes qui-quadrado e odds ratio para comparação de proporções e gráfico de dispersão com coeficiente de correlação linear. RESULTADOS: Dentre x doadores testados, foi encontrada a prevalência de sorologia positiva para o HTLV de 0,02% e indeterminada de 0,09%. Houve uma redução significativa da sorologia positiva para HTLV, no período de 2002 a 2008, em comparação ao período de 1995 a 2001. Dentre os soropositivos, observou predomínio significante no gênero feminino. CONCLUSÕES: Imputamos a queda gradativa de soropositividade no período à exclusão permanente dos doadores de repetição soropositivos e ao aprimoramento dos métodos de triagem clínica e dos testes sorológicos ao longo dos anos com reflexos positivos na segurança transfusional.INTRODUCTION: A retrospective study was conducted in order to assess the prevalence and factors associated with seropositivity for HTLV-1/2 between 1995 and 2008 in Uberaba Regional Blood Center, and to describe the seropositive blood donors in relation to gender, age, marital status, skin color and origin. METHODS: Descriptive statistical analysis, chi-square tests and odds ratios were produced to compare proportions, along with scatter charts with linear correlation coefficients. RESULTS: Among the donors tested, the prevalence of seropositivity for HTLV was found to be 0.02%, with indeterminate results in 0.09%. There was a significant reduction in seropositivity for HTLV between 2002 and 2008, compared with the period from 1995 to 2001. Among the seropositive individuals, females were significantly predominant. CONCLUSIONS

  5. Blood Vessel Tension Tester

    Science.gov (United States)

    1978-01-01

    In the photo, a medical researcher is using a specially designed laboratory apparatus for measuring blood vessel tension. It was designed by Langley Research Center as a service to researchers of Norfolk General Hospital and Eastern Virginia Medical School, Norfolk, Virginia. The investigators are studying how vascular smooth muscle-muscle in the walls of blood vessels-reacts to various stimulants, such as coffee, tea, alcohol or drugs. They sought help from Langley Research Center in devising a method of measuring the tension in blood vessel segments subjected to various stimuli. The task was complicated by the extremely small size of the specimens to be tested, blood vessel "loops" resembling small rubber bands, some only half a millimeter in diameter. Langley's Instrumentation Development Section responded with a miniaturized system whose key components are a "micropositioner" for stretching a length of blood vessel and a strain gage for measuring the smooth muscle tension developed. The micropositioner is a two-pronged holder. The loop of Mood vessel is hooked over the prongs and it is stretched by increasing the distance between the prongs in minute increments, fractions of a millimeter. At each increase, the tension developed is carefully measured. In some experiments, the holder and specimen are lowered into the test tubes shown, which contain a saline solution simulating body fluid; the effect of the compound on developed tension is then measured. The device has functioned well and the investigators say it has saved several months research time.

  6. [Blood donation in urban areas].

    Science.gov (United States)

    Charpentier, F

    2013-05-01

    Medical and technical developments increase the difficulty to provide sufficient safe blood for all patients in developed countries and their sociodemographic and societal changes. Sufficient national blood supply remains a reached, however still actual, challenge. Tomorrow is prepared today: the management of blood donation programs both in line with these developments and with social marketing strategies is one of the keys to success. If the main components of this organization are well known (mobile blood drives in various appropriate environments, and permanent blood donation centers) their proportions in the whole process must evolve and their contents require adaptations, especially for whole blood donation in urban areas. We have to focus on the people's way of life changes related to increasing urbanization of the society and prominent position taken by very large cities. This requires targeting several goals: to draw the attention of the potential blood-giving candidate, to get into position to collect him when he will decide it, to give meaning and recognition to his "sacrifice" (give time rather than donate blood) and to give him desire and opportunity to come back and donate one more time. In this strategy, permanent blood centers in urban areas have significant potential for whole blood collection, highlighted by the decrease of apheresis technology requirements. This potential requires profound changes in their location, conception and organization. The concept of Maison Du Don (MDD) reflects these changes.

  7. 21 CFR 640.6 - Modifications of Whole Blood.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Modifications of Whole Blood. 640.6 Section 640.6...) BIOLOGICS ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Whole Blood § 640.6 Modifications of Whole Blood. Upon approval by the Director, Center for Biologics Evaluation and Research, of a supplement...

  8. Blood Facts and Statistics

    Science.gov (United States)

    ... Facts and Statistics Printable Version Blood Facts and Statistics Facts about blood needs Facts about the blood ... to Top Learn About Blood Blood Facts and Statistics Blood Components Whole Blood and Red Blood Cells ...

  9. Establishment Registration & Device Listing

    Data.gov (United States)

    U.S. Department of Health & Human Services — This searchable database contains establishments (engaged in the manufacture, preparation, propagation, compounding, assembly, or processing of medical devices...

  10. Location Problem of Air Materials Supply Center for Air Force

    Institute of Scientific and Technical Information of China (English)

    王涛; 何亚群; 陶学禹

    2002-01-01

    Based on the analysis of three influencing factors on the air material supply center location, the location model of air material supply center was established. By solving the model, the rational supply center of air materials was also determined.

  11. Carolinas Energy Career Center

    Energy Technology Data Exchange (ETDEWEB)

    Classens, Anver; Hooper, Dick; Johnson, Bruce

    2013-03-31

    Central Piedmont Community College (CPCC), located in Charlotte, North Carolina, established the Carolinas Energy Career Center (Center) - a comprehensive training entity to meet the dynamic needs of the Charlotte region's energy workforce. The Center provides training for high-demand careers in both conventional energy (fossil) and renewable energy (nuclear and solar technologies/energy efficiency). CPCC completed four tasks that will position the Center as a leading resource for energy career training in the Southeast: • Development and Pilot of a New Advanced Welding Curriculum, • Program Enhancement of Non-Destructive Examination (NDE) Technology, • Student Support through implementation of a model targeted toward Energy and STEM Careers to support student learning, • Project Management and Reporting. As a result of DOE funding support, CPCC achieved the following outcomes: • Increased capacity to serve and train students in emerging energy industry careers; • Developed new courses and curricula to support emerging energy industry careers; • Established new training/laboratory resources; • Generated a pool of highly qualified, technically skilled workers to support the growing energy industry sector.

  12. Establishment of Rabbit Model of Sick Sinus Syndrome Combined with Heart-yang Deficiency and Blood Stasis Syndrome%慢性病态窦房结综合征与心阳虚血瘀病证结合模型研究

    Institute of Scientific and Technical Information of China (English)

    李汇博; 刘如秀; 王妮娜; 暴美静; 汪艳丽

    2011-01-01

    Objective To explore the feasibility to establish a rabbit model of sick sinus syndrome combined with heart-yang deficiency and blood stasis syndrome (short as combined model) via surgery.Methods The TCM syndrome model was established by the method of ice wetting, cold stimulation and subcutaneous injection with adrenaline hydrochloride, and the combined model was established by damaging the sinoatrial node with 20% formaldehyde. The general state, body temperature, respiratory frequency, heart rate and rhythm, swimming distance and speed in 6 min, and hemorheology indexes were observed before and after the model of each group established. The TCM syndrome characteristics of the two models were compared according to the clinical diagnostic standard of yang deficiency and blood stasis syndrome. Results After the modle established, rabbits of both groups had lower temperature, higher respiratory frequency and heart rate, lower swimming distance and speed, and higher hemorheology indexes. There were no difference between the two groups in the indexes as mentioned except the heart rate, swimming distance and speed. Conclusion The combined model established by surgery has no difference with the TCM syndrome model in syndrome featrues, and it conforms to the clinical diagnostic standard of yang deficiency and blood stasis syndrome.%目的 探讨手术方法建立病态窦房结综合征(以下简称"病窦综合征")与心阳虚血瘀病证结合模型的可行性.方法 采取冰敷、置于寒冷环境、皮下注射肾上腺素的方法制备非疾病阳虚血瘀证候模型;以2 0%甲醛注射浸润窦房结区建立慢性病窦综合征阳虚血瘀病证结合模型,观察2组兔造模前后一般情况、体温、呼吸频率、心率、心律、6 min游泳时间及速率、血液流变学(全血黏度、血浆黏度、红细胞聚集指数)等指标,根据中医临床阳虚血瘀证的诊断标准,对2种模型的中医证候特点进行比较.结果 2组免造

  13. 前列腺增生症肾虚血瘀证大鼠动物模型的建立与评价%Establishment and evaluation of benign prostatic hyperplasia in rats with deficiency of kidney and blood stasis animal model

    Institute of Scientific and Technical Information of China (English)

    樊新荣; 颜苗; 何清湖

    2013-01-01

    Objectives:To establish and evaluate benign prostate hyperplasia rat animal model with blood stasis due to kidney deficiency. Methods;Using the castration surgery, hormone injections and ice bath method manufacturing BPH with kidney deficiency and blood stasis rat model j this paper investigated the prostate wet weight, prostate index and the content of serum prostate specific acid phosphatase (PAP) , and observed model rats pathological tissue morphology. Results; The whole blood viscosity, plasma viscosity, erythrocyte gathered index and Casson viscosity of rats in model group were significantly higher than that in blank group and sham-operated group, and the difference was statistically significant (P < 0. 05). The content of serum PAP in model group was increased (P < 0. 05 ) , and prostate tissue had been observed visible small blood vessels and congestion, according with blood stasis, thus it is demonstrated that the blood stasis rats model had been done. Conclusions; The rat model for BPH witk kidney deficiency and blood stasis was copied successfully. Production method is simple and the evaluation index is objective, which provides the good experimental foundation and theoretical basis for the study of BPH with kidney deficiency and blood stasis syndrome and the theraputic mechanism of related Traditional Chinese Medicine.%目的:建立前列腺增生症(BPH)肾虚血瘀证大鼠动物模型并进行评价.方法:采用去势手术、激素注射加冰浴方法制作BPH肾虚血瘀证大鼠模型,考察前列腺湿重、前列腺指数和血清前列腺特异性酸性磷酸酶(PAP)含量,观察模型大鼠病理组织形态学.结果:模型组大鼠全血黏度、血浆黏度、红细胞聚集指数和卡松黏度均明显高于空白组和假手术组(P<0.05);模型组血清PAP的含量升高(P<0.05),并且模型组大鼠前列腺组织病理组织学观察可见小血管扩张、充血,符合瘀血的病理表现.结论:该模型制作方法简单,

  14. 妊娠期女性血细胞主要参数生物参考区间建立的初步探讨%Preliminary investigation on the establishment of biological reference intervals about the main parameters of blood cells among pregnant women

    Institute of Scientific and Technical Information of China (English)

    葛雅芳; 沈云岳; 唐振华

    2014-01-01

    目的:建立本实验室妊娠期女性血细胞主要参数的生物参考区间。方法选取331例正常足月分娩的孕妇,追溯其孕期检查记录,用 SAS 8.1软件对孕期间进行的2次血细胞常规检测结果进行统计分析,获得参考区间。结果比较妊娠早期和妊娠晚期的各项血常规检验结果,差异具有统计学意义(P 均<0.05)。参考区间分析显示血小板(PLT)、单核细胞百分比(M %)和嗜碱性粒细胞百分比(B %)检验结果均在现行参考区间内,故继续沿用原有参考区间;血细胞比容(HCT)和嗜酸性粒细胞百分比(E %)检验结果,经验证可合并参考区间;而红细胞计数(RBC)、血红蛋白(Hb)、白细胞计数(WBC)、中性粒细胞百分比(N %)及淋巴细胞百分比(L%)需分组建立不同的参考区间。结论新建的生物参考区间更符合孕期的生理变化,能更好的指导临床诊断和治疗。%Objective To establish the biological reference intervals about the main parameters of blood cells among pregnant women in our laboratory.Methods A total of 331 pregnant women who had normal and term delivery were enrolled.According to their medical records,their 2 reports of pregnancy routine blood cell tests were obtained. The results were analyzed statistically,and the biological reference intervals were calculated by SAS 8.1 software. Results There was statistical significance in all parameters of pregnancy routine blood cell tests between the first and third trimesters (P <0.05).The results of biological reference intervals showed that the 2 sets of data about platelet (PLT),monocyte percentage (M%)and basophilic granulocyte percentage (B %)were all within current biological reference intervals,then the current biological reference intervals could be used for pregnancy.The 2 sets of data about hematocrit (HCT)and eosinophile granulocyte percentage (E %)could be combined to

  15. Establishment and Characterization of a Newly Established Diabetic Gerbil Line.

    Directory of Open Access Journals (Sweden)

    Xiaohong Li

    Full Text Available We aimed to selectively breed a spontaneous diabetic gerbil when a sub-line of inbred gerbil showed increased blood glucose levels was found recently. Then we investigated the characteristics including the serum insulin, triglyceride, cholesterol, leptin, adiponectin and explored the underlying molecular mechanism for the diabetic phenotype.The spontaneous diabetic line of gerbils was selectively inbreed the sub-line of gerbil by monitoring blood glucose of each animal. The serum insulin, adiponectin, and leptin levels were tested using an ELISA kit. The expression levels of GLUT4, Akt, leptin, adiponectin, and calpain 10 (CAPN10 were tested by western blot and Quantitative Real-time PCR (qPCR in liver, skeletal muscle, and white adipose.Our results show that the percentages of animals with FPG≥5.2 (mmol/l, PG2h≥6.8 (mmol/l and both FPG≥5.2 and PG2h≥6.8 (mmol/l were increased with the number of breeding generations from F0 (21.33% to F6 (38.46%. These diabetic gerbils exhibited insulin resistance and leptin resistance as well as decreased adiponectin level in the serum. We also observed decreased expression of adiponectin and increased expression of leptin in the skeletal muscle, respectively.These results indicate that we have primarily established a spontaneous diabetic gerbil line, and the diabetic phenotypes may have been accounted for by altered expression of leptin and adiponectin.

  16. 血液净化中心实施责任个体化护理模式的效果评价%Effect of Responsibility-individualized Nursing Mode in Blood Purification Center

    Institute of Scientific and Technical Information of China (English)

    徐清秀; 符霞; 邝惠冰; 田秀兰

    2013-01-01

    Objective To evaluate the effect of responsibility-individualized nursing mode in blood purification center.Methods Totally 5 184 times of dialyses from January to June 2012,when the responsibility-individualized nursing mode was implemented,were taken as observation group,and 4 752 times of dialyses from July to December 2011,when the nursing mode of hierarchy responsibility-integrated was implemented,as control group.Incidences of dialysis complications (hypotension,hypertension,hypoglycemia,muscle cramps,disequilibrium syndrome,and dialyzer reaction),patients satisfaction degree (transfusion observation,health education,life care,service attitude,and puncture technique),and the nursing quality were compared and evaluated between the two groups.Results Since the implementation of responsibility-individualized nursing for six months,the incidences of dialysis complications decreased significantly (P<0.05),and patients were more satisfied meanwhile nursing quality had been significantly improved (P<0.05,P<0.01,or P<0.001).Conclusion The implementation of responsibility-individualized nursing mode could reduce the incidence of dialysis complications,and improve the nursing quality and satisfaction of patients.%目的 评价在血液净化中心实施责任个体化护理模式的效果.方法 将2012年1-6月实施责任个体化护理模式下70例患者进行的5 184例次血液透析作为观察组,将2011年7-12月在层级全责一体化护理模式下68例患者进行的4 752例次血液透析作为对照组,比较两组患者透析并发症(低血压、高血压、低血糖、肌肉痉挛、失衡综合征、透析器反应)的发生率、患者满意度(输液观察、健康宣教、生活护理、服务态度、穿刺技术)及护理质量(内瘘1次穿刺成功率、透析不适症状发生率、护理缺陷发生率)情况.结果 观察组实施责任个体化护理模式后,透析并发症的发生率较对照组相比显著降低(P<0.05),患

  17. Immunoelectrophoresis - blood

    Science.gov (United States)

    IEP - serum; Immunoglobulin electrophoresis - blood; Gamma globulin electrophoresis; Serum immunoglobulin electrophoresis; Amyloidosis - electrophoresis serum; Multiple myeloma - serum electrophoresis; Waldenström - serum electrophoresis

  18. 探讨血站采血护理人员与青年献血者沟通技巧%Center Blood Stations in Pursuance of Nursing Staff and Young Donors Communication Skills

    Institute of Scientific and Technical Information of China (English)

    李云国

    2016-01-01

    Objective To study and probe into the communication skil s between the blood taking nursing staff and young blood donors in the blood bank. Methods 300 young blood donors and who were donated blood in our blood bank from August 2013 to October 2014 were taken as the research objects,and age between 19 to 27 years old,which the majority of college students. Then,according to the physiological and psychological characteristics of young blood donors,it had a good interaction with the language communication and professional service communication and psychological care. Results 300 young donors were successful blood donation,there was no adverse reaction phenomenon. Through a questionnaire survey to assess the satisfaction of blood donors up to 99%(297/300),tracking statistics two blood donation rate was reached 81.67%(245/300). Conclusion The high quality and effective verbal communication which can help young people get a good and comfortable blood donation experience,that is to ensure the quality of blood output and through the harmonious interaction to enhance the psychological satisfaction of blood donors,and promote the wil ingness of donors in the latter stage of blood donation.%目的:研究探讨血站采血护理人员与青年献血者沟通技巧。方法随机性抽取2013年8月~2014年10月来我血站献血青年300名作为研究对象,年龄在19 ~27岁,其中大学生群体居多,针对青年献血者生理及心理状态特点结合细致的语言交流以及专业性服务沟通和心理护理等方式进行良好互动。结果300名青年献血者均成功献血,未出现不良反应现象;通过问卷调查评估献血者满意度高达99.00%(297/300),追踪统计二次献血率达到81.67%(245/300)。结论优质高效的言语沟通交流帮助青年献血者受到良好舒适的献血体验,即保证了血液输出质量也通过融洽互动交流提升献血者心理满意度,促进献血者后期再次献血意愿。

  19. Quality Management, Quality Assurance and Quality Control in Blood Establishments

    OpenAIRE

    Bolbate, N

    2008-01-01

    Quality terms and the roots of the matter are analyzed according to European Committee’s recommendations. Essence of process and product quality control as well as essence of quality assurance is described. Quality system’s structure including quality control, quality assurance and management is justified in the article.

  20. Star Formation in the Galactic Center

    CERN Document Server

    Kauffmann, Jens

    2016-01-01

    Research on Galactic Center star formation is making great advances, in particular due to new data from interferometers spatially resolving molecular clouds in this environment. These new results are discussed in the context of established knowledge about the Galactic Center. Particular attention is paid to suppressed star formation in the Galactic Center and how it might result from shallow density gradients in molecular clouds.

  1. Understanding Blood Counts

    Science.gov (United States)

    ... Lab and Imaging Tests Understanding Blood Counts Understanding Blood Counts Understanding Blood Counts SHARE: Print Glossary Blood cell counts give ... your blood that's occupied by red cells. Normal Blood Counts Normal blood counts fall within a range ...

  2. The Establishment and Research on Evaluation System for Core Competence and Technological Support Capability of International Travel and Healthcare Centers in Entry- Exit Inspection and Quarantine System%国际旅行卫生保健中心核心能力及技术支撑能力建设评价体系的建立与研究

    Institute of Scientific and Technical Information of China (English)

    秦佳; 章琪; 杨柳; 李俊; 周启明; 韩晓辉; 方筠; 叶魏

    2015-01-01

    Objective] To establish the evaluation system for core competence and technological support capability of International Travel and Healthcare centers in Entry-Exit Inspection and Quarantine system based on current situation and problem-oriented research,in order to provide a guidance and orientation in capacity building practice. [Methods] A literature research was made for literatures and relevant docu-ments of National Ministry of health and General Administration of Quality Supervision,Inspection and Quarantine(AQSIQ). An indicator system evaluation method was conducted from both theoretical and practical perspective according to the research result. Shanghai International Travel and Healthcare center was chosen as a sample. [Results] In accordance with the data,experiences and facts acquired,we es-tablished the evaluation system as target level,access level and indicator level. The case study showed that the core competence and technological support capability of Shanghai center was strong. But the in-formation management capability and public health emergency control ability should be enhanced. [Con-clusion] The evaluation system for core competence and technological support capability of International Travel and Healthcare centers has great practical significance and theory value,thus could play as a direc-tive role in the process of core competence and technology support ability construction.%[目的]对检验检疫系统国际旅行卫生保健中心的核心能力及技术支撑能力建设内涵及评价体系支持理论进行探索,建立与口岸卫生检疫技术保障要求相适应的评价体系。[方法]应用文献研究法分析国内外文献和上级部门印发的有关文件;根据分析结果,从理论和实践上阐述核心能力及技术支撑能力建设的具体内涵,构建其评价体系;搜集整理典型案例,应用案例研究法进行验证。[结果]经研究建立3个层次的指标体系,具体由目标层、

  3. BLOOD DONATION

    CERN Multimedia

    SC Unit

    2008-01-01

    A blood donation, organized by EFS (Etablissement Français du Sang) of Annemasse will take place On Wednesday 12 November 2008, from 8:30 to 16:00, at CERN Restaurant 2 If possible, please, bring your blood group Card.

  4. Blood donation

    CERN Multimedia

    GS Department

    2009-01-01

    A blood donation is organised by the Cantonal Hospital of Geneva On Thursday 19 March 2009 from 9 a.m. to 5 p.m. CERN RESTAURANT 2 Number of donations during the last blood donations :135 donors in July 2008 122 donors in November 2008 Let’s do better in 2009 !!! Give 30 minutes of your time to save lives...

  5. Tainted blood

    DEFF Research Database (Denmark)

    Deleuran, Ida; Sheikh, Zainab Afshan; Hoeyer, Klaus

    2015-01-01

    study of the historical rise and current workings of safety practices in the Danish blood system. Here, we identify a strong focus on contamination in order to avoid 'tainted blood', at the expense of working with risks that could be avoided through enhanced blood monitoring practices. Of further...... significance to this focus are the social dynamics found at the heart of safety practices aimed at avoiding contamination. We argue that such dynamics need more attention, in order to achieve good health outcomes in transfusion medicine. Thus, we conclude that, to ensure continuously safe blood systems, we...... need to move beyond the bifurcation of the social and medical aspects of blood supply as two separate issues and approach social dynamics as key medical safety questions....

  6. What Happens to Donated Blood?

    Science.gov (United States)

    ... week. Learn About Blood Blood Facts and Statistics Blood Components Whole Blood and Red Blood Cells Platelets Plasma ... About Blood Blood Facts and Statistics Blood Types Blood Components What Happens to Donated Blood Blood and Diversity ...

  7. Centering research

    DEFF Research Database (Denmark)

    Katan, Lina Hauge; Baarts, Charlotte

    and collected 24 portfolios in which students reflect auto-ethnographically on their educational practices. Analyzing this qualitative material, we explore how researchers and students respectively read and write to develop and advance their thinking in those learning processes that the two groups fundamentally...... share as the common aim of both research and education. Despite some similarities, we find that how the two groups engage in and benefit from reading and writing diverges significantly. Thus we have even more reason to believe that centering practice-based teaching on these aspects of research is a good...

  8. Cumplimiento de las normas de la calidad de atención establecidas por el compromiso de gestión en los pacientes diabéticos del Área de Salud de Alajuelita, en el periodo de enero a julio de 2007 Achivement of Patient Care Standards established by the Agreement on Management for Diabetic Patients in the Alajuelita Health Center from January to July, 2007

    Directory of Open Access Journals (Sweden)

    Raj Chapagain K

    2012-09-01

    care standards for patients with diabetes who attend the Alajuelita Health Center and the determinant factors for non-compliance, to propose suggestions aimed at improving it. Materials and methods: This is an analytical observational cross-sectional study based on the data in the medical records of the diabetic patients. Consecutive sampling was used to analyzethemedical records of 500 diabetic patients of the Alajuelita Health Center, in order to establish the level of compliance with quality standards of care for diabetic patients, between January and July 2007. The data collection was performed by a precoded sheet, whose design was based on the one used for the control of diabetic patients under the national management commitments. Forty health workers from the Area, directly related to the fulfillment of the rules of Management Commitment, were interviewed. Results: The study identified that blood sugar level was not indicated to a total of 14 patients (2.8%. From the total of patients studied, 197(39.4% had a blood glucose level between 101150mg/dl; only 50 patients (10% had a blood glucose level 300, which represents a 12.6% of inadequately controlled patients. Only 25% of the patients had the HbA1c at or below 7%. A 26.3% of diabetic patients maintained this indicator between 7 and 9.9% and 7.8% above 10%. In regard to the physical plant, 32.5% of staff thinks that the physical plant of ASA is good, 22.55 think it is very good and 20% believes it is regular. Conclusion: Only 25% of diabetic patients assessed as adequate the attention received at the Alajuelita Health Area, according to the parameters of the management commitment

  9. Hemoglobinas variantes em doadores de sangue do Centro de Hematologia e Hemoterapia do estado do Piauí (Hemopi: conhecendo o perfil epidemiológico para construir a rede de assistência Hemoglobin S variants in blood donors of the Hematology and Hemotherapy Center of the state of Piauí (Hemopi: understanding the epidemiological profile to create a support network

    Directory of Open Access Journals (Sweden)

    Leonardo F. Soares

    2009-01-01

    Full Text Available The most highly prevalent inherited disease in Brazil and in the world, sickle cell anemia, is considered a public health problem. Characterized by homozygosis for the hemoglobin S gene, the individual has a range of signs and symptoms that require careful treatment. The sickle cell trait is characterized by heterozygosis for the hemoglobin S gene, however the carrier does not express the disease. In the current study we aimed at verifying the presence of the sickle cell trait in 1000 blood donors of the Hematology and Hemotherapy Center of the State of Piauí (Hemopi in the period from October 2007 to April 2008. After analysis by alkaline and acid electrophoresis, positive cases were confirmed by molecular biology. We obtained rates of 3.4% for hemoglobin AS and 5% for hemoglobin AC, with a total frequency of 3.9% in the total of 1,000 blood donors.

  10. NASA New England Outreach Center

    Science.gov (United States)

    2002-01-01

    The NASA New England Outreach Center in Nashua, New Hampshire was established to serve as a catalyst for heightening regional business awareness of NASA procurement, technology and commercialization opportunities. Emphasis is placed on small business participation, with the highest priority given to small disadvantaged businesses, women-owned businesses, HUBZone businesses, service disabled veteran owned businesses, and historically black colleges and universities and minority institutions. The Center assists firms and organizations to understand NASA requirements and to develop strategies to capture NASA related procurement and technology opportunities. The establishment of the NASA Outreach Center serves to stimulate business in a historically underserved area. NASA direct business awards have traditionally been highly present in the West, Midwest, South, and Southeast areas of the United States. The Center guides and assists businesses and organizations in the northeast to target opportunities within NASA and its prime contractors and capture business and technology opportunities. The Center employs an array of technology access, one-on-one meetings, seminars, site visits, and targeted conferences to acquaint Northeast firms and organizations with representatives from NASA and its prime contractors to learn about and discuss opportunities to do business and access the inventory of NASA technology. This stimulus of interaction also provides firms and organizations the opportunity to propose the use of their developed technology and ideas for current and future requirements at NASA. The Center provides a complement to the NASA Northeast Regional Technology Transfer Center in developing prospects for commercialization of NASA technology. In addition, the Center responds to local requests for assistance and NASA material and documents, and is available to address immediate concerns and needs in assessing opportunities, timely support to interact with NASA Centers on

  11. Centered Sublattice and its Application

    Institute of Scientific and Technical Information of China (English)

    宋振明; 徐扬; 等

    1993-01-01

    In this paper,the concept of the centered sublattice is introduceed for lattice theory and the dis-composition theorem of a lattice is given.Based on the centered sublattice,we give some new descriptions of a modular lattice,a distributive lattice,a complemented lattice and an relatively complemented lattice,etc.These new decriptions established now researching methods for lattice theory.

  12. Electrolysis activities at FCH Test Center

    DEFF Research Database (Denmark)

    Ravn Nielsen, Eva; Nygaard, Frederik Berg

    FCH Test Center for fuel cell and hydrogen technologies was established in 2010 at Risø DTU in Denmark. Today, the test center is part of DTU Energy Conversion. The center gives industry access to advanced testing and demonstration of components and systems. A number of national projects and EU...... projects regarding water electrolysis involve FCH Test Center as a partner. This presentation gives an overview of the activities....

  13. Secular Religious Establishment

    DEFF Research Database (Denmark)

    Lægaard, Sune

    2013-01-01

    Secularism as a political doctrine claims that religion and politics should be separated. The compatibility question is whether secularism can accept some forms of religious establishment in the form of institutional linkages between state and organised religion. I argue that the answer to the co......Secularism as a political doctrine claims that religion and politics should be separated. The compatibility question is whether secularism can accept some forms of religious establishment in the form of institutional linkages between state and organised religion. I argue that the answer...... to the compatibility question is not obvious and requires a systematic analysis of secularism. Based on a distinction between a general concept and specific conceptions of secularism I offer a general structure for conceptions of secularism that incorporates both a) basic values, e.g. political equality and freedom...... of secularism are therefore compatible with some forms of religious establishment. I illustrate the use of the framework for discussion of particular establishment cases and how the framework provides a structure for the normative discussion about which conception of secularism to accept....

  14. The Implementation of 2U Platelets Collected at the Huaian Blood Center%2U单采血小板的采集在淮安市中心血站的实施

    Institute of Scientific and Technical Information of China (English)

    滕平; 谢峰

    2015-01-01

    目的 为了保证献血者在捐献双份血小板后,体内剩余血小板仍能达到正常人水平,保障献血者的健康;另外也要使终产品符合国标的质量要求,达到患者的安全治疗需要的剂量. 方法 依据献血者体重和采前血小板计数,确定采集双份血小板的标准,对双份献血者体重的最低要求是:男≥60 kg,女≥55 kg;采前计数血小板的最低值为≥200×109/L.结果 经血细胞分离机采集后,对献血者重新抽样检查和对终产品进行验证,采集双份血小板后,献血者体内剩余血小板≥1.0×1011/L的正常人水平;采集后的终产品血小板计数≥5.0×1011/袋,白细胞≤5×108/袋,红细胞≤8× 109/袋,都能达到国标要求.结论 符合条件的献血者1次采集双份血小板安全可行,这样既能解决单采血小板供者的不足,减少患者输注血小板后抗体产生的机会,同时也可大大节约单采血小板成本.%Objective To ensure blood donors after double platelet donation, remaining in vivo platelet can still reach nor-mal level, to keep the donors of health;in addition to the final products to meet the requirements of the national standard of quality, to reach the safe treatment of the patients required dose. Methods According to the blood donation weight and re-covery of platelet count, the criteria for determining double samples of platelet, double blood donation is the weight of the minimum requirements: male is more than or equal to 60 kg, female is more than or equal to 55 kg. The lowest values of platelet count is equal or more than 200×109/L. Results Blood cell separator after collection, the blood donors to sampling inspection and the final product verification, after double platelet collection and normal human level of blood donors in residual platelet is more than or equal to 1.0×1011/L; after collection of the final products platelet count is greater than or e-qual to 5.0 ×1011/bag, white blood cell is less than or

  15. Blood Typing

    Science.gov (United States)

    ... if you need repeated transfusions, as sickle cell anemia and thalassemia patients do. If blood transfusions are not closely ... the News Article Index About This Site Send Us Your Comments For ...

  16. Blood Disorders

    Science.gov (United States)

    ... people with blood disorders. Magnitude of the Problem Complications from deep vein thrombosis (DVT) kill more people each year than breast cancer, motor vehicle accidents, and HIV combined. Sickle cell trait ...

  17. What's Blood?

    Science.gov (United States)

    ... Rh" because scientists found it while studying Rhesus monkeys. If your blood is positive, you have this ... doctor. © 1995- The Nemours Foundation. All rights reserved. Images provided by The Nemours Foundation, iStock, Getty Images, ...

  18. Application of Delphi Method to Establish Yancheng the Third People's Hospital Disinfection Supply Center Staff Training Evaluation Index%应用Delphi法建立盐城第三人民医院消毒供应中心人员培训评价指标

    Institute of Scientific and Technical Information of China (English)

    尤琼

    2015-01-01

    目的:该文主要是对应用Delphi法建立盐城第三人民医院消毒供应中心人员培训评价指标的分析。方法根据消毒供应科目前的情况采用Delphi法确定盐城第三人民医院消毒供应中心人员培训的评价指标。结果专家的积极性很高(回收率为100%),专家权威性很高(系数为0.87);各个指标的变异系数范围都在0.00~0.23之间;协调系数各级指标分别为0.353、0.462、0.696,差异有统计学意义(P<0.01)。最后确立了盐城第三人民医院消毒供应中心人员培训评价指标。为人员资质、培训资源、培训管理、培训效果4个山鸡指标,以及12个二级指标,40个三级指标。结论该次研究采用Delphi法对该院消毒供应中心的人员培训指标进行确定符合该医院消毒供应中心临床工作的实际需求,同时对促进医院消毒供应中心的培训体制的建设以及提高培训质量都具有重要的意义。%Objective This paper is mainly based analysis Yancheng Third People's Hospital disinfection supply center per-sonnel training evaluation of the application of the Delphi method. Methods According to the current situation sterile sup-ply department determined using the Delphi method Yancheng Third People's Hospital sterile supply center staff training evaluation. Results Experts highly motivated (recovery of 100%), high expert authority (coefficient of 0.87); coefficient of variation range of each index are between 0.00 to 0.23; coordination at all levels of index coefficients were 0.353,0.462,0.696 The difference was statistically significant (P<0.01). Finally established the Third People's Hospital of Yancheng disinfection supply center personnel training evaluation. As qualified personnel, training resources, training man-agement, training effect four pheasant indicators and 12 secondary indicators, 40 three indicators. Conclusion The study used the Delphi method for staff training hospital central sterile

  19. Artificial blood.

    OpenAIRE

    1983-01-01

    #Blood substitutes have been developed for almost a century. The various type of artificial blood was continuously available on the market. The theme of this report is to identify the best substitute in emergency situation for some patients and science students. The definition of best is given; thus, as the vital part of the report, the comparison between them is described and discussed. Modified hemoglobin, bovine-based hemoglobin and PFCs are three basic types. In terms of the perfor...

  20. High Blood Cholesterol: What You Need to Know

    Science.gov (United States)

    ... Audiences Contact The Health Information Center High Blood Cholesterol: What You Need To Know Table of Contents ... Lifestyle Changes (TLC) Drug Treatment Resources Why Is Cholesterol Important? Your blood cholesterol level has a lot ...

  1. COMPUTATIONAL SCIENCE CENTER

    Energy Technology Data Exchange (ETDEWEB)

    DAVENPORT, J.

    2005-11-01

    The Brookhaven Computational Science Center brings together researchers in biology, chemistry, physics, and medicine with applied mathematicians and computer scientists to exploit the remarkable opportunities for scientific discovery which have been enabled by modern computers. These opportunities are especially great in computational biology and nanoscience, but extend throughout science and technology and include, for example, nuclear and high energy physics, astrophysics, materials and chemical science, sustainable energy, environment, and homeland security. To achieve our goals we have established a close alliance with applied mathematicians and computer scientists at Stony Brook and Columbia Universities.

  2. Center of excellence in laser medicine

    Energy Technology Data Exchange (ETDEWEB)

    Parrish, J.A.

    1992-01-01

    Achievements during the first six months of funding to prepare for a Center of Excellence in biomedical laser development include limited specific research projects within the Center's three broad interest areas, and program development to establish the Center and its activities. Progress in the three interest areas -- new medical laser systems development, optical diagnostics, and photosensitization, is reported. Feasibility studies and prototype development were emphasized, to enhance establishing a substantial Center through future support. Specific projects are an optimized laser-catheter system for reversal of vasospasm; optical detection of major skin burn depth and cancers using fluorescent drugs, and photosensitization of vascular tissues. In addition, an interdepartmental Laser Center was established at MGH to enhance collaborations and institutional committment to the Center of Excellence. Competitive postdoctoral research fellowships, with provision for matching funds from other departments, have been announced.

  3. Blood Transfusion and Donation

    Science.gov (United States)

    ... receiving the blood transfusion. To keep blood safe, blood banks carefully screen donated blood. The risk of catching ... one or more times before the surgery. A blood bank will store your blood for your use. NIH: ...

  4. Blood (For Parents)

    Science.gov (United States)

    ... Old Feeding Your 1- to 2-Year-Old Blood KidsHealth > For Parents > Blood A A A What's ... about the mysterious, life-sustaining fluid called blood. Blood Basics Two types of blood vessels carry blood ...

  5. Catecholamine blood test

    Science.gov (United States)

    Norepinephrine -- blood; Epinephrine -- blood; Adrenalin -- blood; Dopamine -- blood ... A blood sample is needed. ... the test. This is especially true if both blood and urine catecholamines are to be measured. You ...

  6. Biology of Blood

    Science.gov (United States)

    ... here for the Professional Version Home Blood Disorders Biology of Blood Overview of Blood Resources In This ... Version. DOCTORS: Click here for the Professional Version Biology of Blood Overview of Blood Components of Blood ...

  7. Blood Clotting and Pregnancy

    Medline Plus

    Full Text Available ... Blood Basics Blood Disorders Anemia Bleeding Disorders Blood Cancers Blood Clots Blood Clotting and Pregnancy Clots and ... Increased maternal age Other medical illness (e.g., cancer, infection) back to top How are Blood Clots ...

  8. State Analysis of the Apheresis Platelet Donors in Dali Blood Center%大理州中心血站机采血小板献血者结构状况分析

    Institute of Scientific and Technical Information of China (English)

    李剑波; 杨天富; 王永均; 杨宇珠; 季雯婕

    2015-01-01

    目的:了解大理州无偿机采血小板献血人群的结构及分布特征,为无偿献血招募提供科学依据,确保本地区机采血小板的临床供应.方法:用穿越血站管理信息系统中统计模块收集2005年至2013年在血站无偿捐献机采血小板的献血者资料,进行数据统计分析.结果:2005年至2013年共有机采血小板献血者889人次.其中,男性显著多于女性,占89.31%;年龄以25~35岁、36~45岁两个年龄段为主;初中及以下学历所占比例较大,占66.14%;职业以农民为主,占62.77%;血型分布特征为A>O>B>AB.结论:有针对性地做好无偿机采血小板献血宣传招募工作,建立一支稳定的机采血小板献血者队伍,以满足临床需要.%Objective:To understand the state and distribution of the voluntary apheresis platelet donors in Dali;to provide scientific basis for the recruitment of blood donation without compensation; and to ensure the local clinical supply of the apheresis platelet. Methods: The statistical module in the through blood stations management information system was used to collect the data from the apheresis platelet donors who voluntarily donated in our blood bank from 2005 to 2013 for statistical analysis. Results:The number of the blood donors from 2005 to 2013 is 889. Among them, the number of the men is obviously larger than that of women , accounting for 89.31%. There are two main age groups:aged from 25 to 35 and from 36 to 45. Most of them are junior school graduates and below, accounting for 66.14%;About 62.77%of them are famers;The characteristic of blood type distribution is A>O>B>AB. Conclusion:To satisfy clinical needs good recruitment of free donors and stable donation populator are important.

  9. Blood and war.

    Science.gov (United States)

    Hedley-Whyte, John; Milamed, Debra R

    2010-09-01

    In 1894 Ulsterman and pathologist Almroth Wright described the citation of blood. Twenty-one years later it was introduced into wartime and clinical practice. Harvard Medical School had a large part in providing Colonel Andrew Fullerton, later Professor of Surgery, Queen's Belfast, with the intellectual and practical help for the Allies to deploy blood on the post-Somme Western Front and in Salonika. The key investigators and clinicians were Americans and Canadians who with Fullerton and Wright instructed the Allies. The key enablers were two Harvard-trained surgeons surnamed Robertson-Oswald H. ("Robby") and L. Bruce (no relation). Physician Roger I. Lee of Harvard, surgeon George W Crile of Cleveland, Peyton Rous of the Rockefeller Institute and Richard Lewisohn of Mount Sinai Hospital, both located in the Upper East Side of New York City, played key roles.By Armistice in 1918, indirect citrated nutrient-enhanced blood transfusion was widely used by the Allies. Geoffrey Keynes was taught the techniques of blood transfusion by Dr. Benjamin Harrison Alton of Harvard at a Casualty Clearing Station near Albert at the time of the Battle of Passchendaele. Professor "Robby" Robertson, DSO, Sir Geoffrey Keynes and Sir Thomas Houston established blood banking.

  10. Managing your blood sugar

    Science.gov (United States)

    Hyperglycemia - control; Hypoglycemia - control; Diabetes - blood sugar control; Blood glucose - managing ... Know how to: Recognize and treat low blood sugar (hypoglycemia) Recognize and treat high blood sugar (hyperglycemia) ...

  11. MHC Class I Chain-Related Gene A (MICA) Donor-Recipient Mismatches and MICA-129 Polymorphism in Unrelated Donor Hematopoietic Cell Transplantations Has No Impact on Outcomes in Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, or Myelodysplastic Syndrome: A Center for International Blood and Marrow Transplant Research Study.

    Science.gov (United States)

    Askar, Medhat; Sobecks, Ronald; Wang, Tao; Haagenson, Mike; Majhail, Navneet; Madbouly, Abeer; Thomas, Dawn; Zhang, Aiwen; Fleischhauer, Katharina; Hsu, Katharine; Verneris, Michael; Lee, Stephanie J; Spellman, Stephen R; Fernández-Viña, Marcelo

    2017-03-01

    Single-center studies have previously reported associations of MHC Class I Chain-Related Gene A (MICA) polymorphisms and donor-recipient MICA mismatching with graft-versus-host disease (GVHD) after unrelated donor hematopoietic cell transplantation (HCT). In this study, we investigated the association of MICA polymorphism (MICA-129, MM versus MV versus VV) and MICA mismatches after HCT with 10/10 HLA-matched (n = 552) or 9/10 (n = 161) unrelated donors. Included were adult patients with a first unrelated bone marrow or peripheral blood HCT for acute lymphoblastic leukemia, acute myeloid leukemia, or myelodysplastic syndrome that were reported to the Center for International Blood and Marrow Transplant Research between 1999 and 2011. Our results showed that neither MICA mismatch nor MICA-129 polymorphism were associated with any transplantation outcome (P acute GVHD grades II to IV (HR, 1.4; P = .013) There were no significant interactions between MICA mismatches and HLA matching (9/10 versus 10/10). In conclusion, the findings in this cohort did not confirm prior studies reporting that MICA polymorphism and MICA mismatches were associated with HCT outcomes.

  12. Do blood-borne calcifying nanoparticles self-propagate?

    Directory of Open Access Journals (Sweden)

    Grace Mathew

    2008-06-01

    Full Text Available Grace Mathew1, David S McKay2, Neva Çiftçioglu21Nanobac Pharmaceuticals Inc, Johnson Space Center, Houston, TX, USA; 2NASA Johnson Space Center, Houston, TX, USAAbstract: The nanotechnology industry is currently in the process of producing new nanoparticles. The biological activity of nanoparticles including adverse as well as beneficial effects tends to increase as their size decreases. The smaller the particles are, the greater their bioactivity and toxicity. Thus, one can easily conjecture the impact of a nanoparticle if it could also self-replicate. This in vitro study reveals the self-propagating ability of unique calcifying nanoparticles (CNP that can be as small as 50 nm in size and found in blood, blood products, and calcified soft tissues. Although specific detection techniques, morphological characteristics and biomineralizing properties of CNP are well established, their genomic information and self-propagating capability have always been challenged. The objective of this study is to document the propagation of CNP under physiological conditions, using inverted light microscopy (LM and the Biostation IM time-lapse imaging system. Their detailed morphological structure was examined using scanning (SEM and transmission (TEM electron microscopy. This present study, in conjunction with previous findings of metabolic activity, antibiotic sensitivity, antibody specificity, morphological aspects and infectivity, validates CNP as self-replicators. Therefore these sterile-filterable, blood-borne nanoparticles should be of concern to the nanomedicine industry.Keywords: calcifying nanoparticles, time-lapse photography, self-replication, apatite

  13. Vital Signs - High Blood Pressure

    Centers for Disease Control (CDC) Podcasts

    2012-10-02

    In the U.S., nearly one third of the adult population have high blood pressure, the leading risk factor for heart disease and stroke - two of the nation's leading causes of death.  Created: 10/2/2012 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 10/17/2012.

  14. Iron deficiency in blood donors

    Directory of Open Access Journals (Sweden)

    Armando Cortés

    2005-03-01

    Full Text Available Context: Blood donation results in a substantial loss of iron (200 to 250 mg at each bleeding procedure (425 to 475 ml and subsequent mobilization of iron from body stores. Recent reports have shown that body iron reserves generally are small and iron depletion is more frequent in blood donors than in non-donors. Objective: The aim of this study was to evaluate the frequency of iron deficiency in blood donors and to establish the frequency of iron deficiency in blood donors according to sex, whether they were first-time or multi-time donors. Design: From march 20 to April 5, 2004, three hundred potential blood donors from Hemocentro del Café y Tolima Grande were studied. Diagnostic tests: Using a combination of biochemical measurements of iron status: serum ferritin (RIA, ANNAR and the hemoglobin pre and post-donation (HEMOCUE Vital technology medical . Results: The frequency of iron deficiency in potential blood donors was 5%, and blood donors accepted was 5.1%; in blood donors rejected for low hemoglobin the frequency of iron deficiency was 3.7% and accepted blood donors was 1.7% in male and 12.6% in female. The frequency of iron deficiency was higher in multi-time blood donors than in first-time blood donors, but not stadistic significative. Increase nivel accepted hemoglobina in 1 g/dl no incidence in male; in female increase of 0.5 g/dl low in 25% blood donors accepted with iron deficiency, but increased rejected innecesary in 16.6% and increased is 1 g/dl low blood donors female accepted in 58% (7/12, but increased the rejected innecesary in 35.6%. Conclusions: We conclude that blood donation not is a important factor for iron deficiency in blood donors. The high frequency of blood donors with iron deficiency found in this study suggests a need for a more accurate laboratory trial, as hemoglobin or hematocrit measurement alone is not sufficient for detecting and excluding blood donors with iron deficiency without anemia, and ajustes hacia

  15. CAST Xi'an Branch Established

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ China Academy of Space Technology (CAST) Xi'an Branch was established on April 8,2008.The new branch consists of the headquarters of the former Xi'an Institute of Space Radio Technology (XISRT) of CAST and five former subsidiaries of the XISRT,i.e.the Institute of Space Electronic Technology,the Institute of Microwave Technology,the Institute of Space Antenna Technology,the Manufacturing Center for Space Electronics and Civilian High-tech Company.

  16. Center of Excellence in laser medicine. Progress performance report

    Energy Technology Data Exchange (ETDEWEB)

    Parrish, J.A.

    1993-04-29

    Achievements during the last 12 months of funding to initiate a Center of Excellence in biomedical laser development include: seven specific research projects within the Center`s three broad interest areas, and program development to establish the MGH Laser Center and its activities. Progress in the three interest areas namely new medical laser systems development, optical diagnostics and photo sensitization is reported. Feasibility studies and prototype development were emphasized, to enhance establishing a substantial Center through future support. Specific projects are outlined below. In addition, the interdepartmental MGH Laser Center`s activities and accomplishments.

  17. Blood Basics

    Science.gov (United States)

    ... of ASH ASH Meeting on Hematologic Malignancies Consultative Hematology Course ASH Meeting on Lymphoma Biology ASH Workshop on Genome Editing Publications Blood The Hematologist ASH Clinical News ASH Self-Assessment Program Hematology , ASH Education Program About Awards Membership ASH Foundation ...

  18. Blood Clots

    Science.gov (United States)

    ... of ASH ASH Meeting on Hematologic Malignancies Consultative Hematology Course ASH Meeting on Lymphoma Biology ASH Workshop on Genome Editing Publications Blood The Hematologist ASH Clinical News ASH Self-Assessment Program Hematology , ASH Education Program About Awards Membership ASH Foundation ...

  19. Mississippi Technology Transfer Center

    Science.gov (United States)

    1987-01-01

    The Mississippi Technology Transfer Center at the John C. Stennis Space Center in Hancock County, Miss., was officially dedicated in 1987. The center is home to several state agencies as well as the Center For Higher Learning.

  20. Re-establishing dignity

    DEFF Research Database (Denmark)

    Høy, Bente; Hall, E.O.C

    2012-01-01

    In western countries, the older population is increasing and with age follows a risk of un-health. Every fifth hospital patient is above 65 years of age. As a consequence, nursing care to older patients is a significant but tacit nursing issue. The aim of this study was to explore Danish clinical...... nurses’ experiences of caring for older hospital patients. The study was based on Benner and Wrubel’s phenomenological notion that caring as a special kind of involvement, a grasp of a situation in terms of its meaning, is primary in nursing. A qualitative secondary analysis of data from an interview...... study with 29 nurses and nurse assistants was performed following Van Manen’s hermeneutic phenomenology. Findings show that caring mainly concerns ‘re-establishing dignity’ especially through ‘seeing the patient as a unique person’, ‘assisting in getting rid of the bed’ and ‘supporting patient...

  1. Establishing effective working relationships.

    Science.gov (United States)

    Houghton, Trish

    2016-02-24

    This article, the second in a series of 11, provides support and offers advice to new and existing mentors and practice teachers to enable them to progress in their role and develop a portfolio of evidence. In particular, the article discusses how to establish effective working relationships and emphasises the importance of the student-mentor or student-practice teacher relationship. It examines the essential qualities, attributes and characteristics of an effective mentor or practice teacher. The article provides learning activities and suggests ways in which mentors and practice teachers can undertake various self-assessments, enabling them to gather relevant evidence to demonstrate how they can meet and maintain the requirements for these roles as stipulated by the Nursing and Midwifery Council.

  2. Telework centers as local development

    DEFF Research Database (Denmark)

    Lorentzen, Anne

    2013-01-01

    projects. A record of the development challenges of the two host municipalities Jammerbugt and Brønderslev, to contextualize the telework centers in the local context. And finally a preliminary analysis and discussion of the two telework centers in relation to their potential community benefits......This paper discusses the establishment of distant work centers as an element in local development strategies in rural areas with a particular view on two new telework centers in Region North Denmark Distant work is a phenomenon on the rise, due to the development of the internet on the one hand...... regardless of location, as long as there is access to internet. Not only firms, but individual labor is potentially liberated from the logic of physical location and proximity. Technically speaking ‘geography is dead’ and the clustering of new service jobs in big cities is no longer a technical necessity...

  3. Data Center Optimization Initiative Strategic Plans

    Data.gov (United States)

    Social Security Administration — On August 1, 2016, the Office of Management and Budget issued memorandum M-16-19, establishing the Data Center Optimization Initiative (DCOI). The DCOI, as described...

  4. Center for the Study of Traumatic Stress

    Data.gov (United States)

    Federal Laboratory Consortium — As part of the Department of Psychiatry of our federal medical school, the Uniformed Services University of the Health Sciences (USUHS), the Center was established...

  5. Blood pressure measurement

    Science.gov (United States)

    Diastolic blood pressure; Systolic blood pressure; Blood pressure reading; Measuring blood pressure ... or your health care provider will wrap the blood pressure cuff snugly around your upper arm. The lower ...

  6. Blood Count Tests

    Science.gov (United States)

    Your blood contains red blood cells (RBC), white blood cells (WBC), and platelets. Blood count tests measure the number and types of cells in your blood. This helps doctors check on your overall health. ...

  7. Investigation on artificial blood or substitute blood replace the natural blood.

    Science.gov (United States)

    Keyhanian, Sh; Ebrahimifard, M; Zandi, M

    2014-01-01

    Blood is a liquid tissue in which dissolved with abundant chemical factors and millions of different cells The reduction of unwanted side effects, especially diseases that emerge through blood such as HIV and hepatitis, has a significant role for modern medicine of transfusion and transplantation. The issues and costs of human blood collection and storage, direct this procedure towards the use of alternatives blood. Two important research fields of this area were oxygen carriers based on hemoglobin and perfluoro chemicals. While they do not have the same quality as the blood cell products, the oxygen carrier solutions have potential clinical and non-clinical applications. The result showed that these products can reach to the body tissues easier than normal red blood cells, and can control the oxygen directly. The final aim of transfusion is to establish a transfusion system with no side effects, and the fact that oxygen carrier artificial blood has this property. The article attempts to step towards solving some problems of blood transfusion through describing the properties of artificial blood alternatives.

  8. Establishing a Comprehensive Wind Energy Program

    Energy Technology Data Exchange (ETDEWEB)

    Fleeter, Sanford [Purdue University

    2012-09-30

    This project was directed at establishing a comprehensive wind energy program in Indiana, including both educational and research components. A graduate/undergraduate course ME-514 - Fundamentals of Wind Energy has been established and offered and an interactive prediction of VAWT performance developed. Vertical axis wind turbines for education and research have been acquired, instrumented and installed on the roof top of a building on the Calumet campus and at West Lafayette (Kepner Lab). Computational Fluid Dynamics (CFD) calculations have been performed to simulate these urban wind environments. Also, modal dynamic testing of the West Lafayette VAWT has been performed and a novel horizontal axis design initiated. The 50-meter meteorological tower data obtained at the Purdue Beck Agricultural Research Center have been analyzed and the Purdue Reconfigurable Micro Wind Farm established and simulations directed at the investigation of wind farm configurations initiated. The virtual wind turbine and wind turbine farm simulation in the Visualization Lab has been initiated.

  9. Establishing lunar resource viability

    Science.gov (United States)

    Carpenter, J.; Fisackerly, R.; Houdou, B.

    2016-11-01

    Recent research has highlighted the potential of lunar resources as an important element of space exploration but their viability has not been demonstrated. Establishing whether or not they can be considered in future plans is a multidisciplinary effort, requiring scientific expertise and delivering scientific results. To this end various space agencies and private entities are looking to lunar resources, extracted and processed in situ, as a potentially game changing element in future space architectures, with the potential to increase scale and reduce cost. However, before any decisions can be made on the inclusion of resources in exploration roadmaps or future scenarios some big questions need to be answered about the viability of different resource deposits and the processes for extraction and utilisation. The missions and measurements that will be required to answer these questions, and which are being prepared by agencies and others, can only be performed through the engagement and support of the science community. In answering questions about resources, data and knowledge will be generated that is of fundamental scientific importance. In supporting resource prospecting missions the science community will de facto generate new scientific knowledge. Science enables exploration and exploration enables science.

  10. Tendencia del perfil de sensibilidad antimicrobiana de los aislamientos de sangre en un hospital oncológico (1998-2003 Trend of antimicrobial drug-susceptibility of blood isolates at an oncological center (1998-2003

    Directory of Open Access Journals (Sweden)

    Patricia Cornejo-Juárez

    2005-07-01

    Full Text Available OBJETIVO: Describir la frecuencia de la resistencia en microrganismos aislados en cultivos de sangre en pacientes de un hospital oncológico de tercer nivel. MATERIAL Y MÉTODOS: De enero de 1998 a diciembre de 2003, en el Instituto Nacional de Cancerología se desarrolló un estudio retrospectivo en el cual se obtuvieron cepas de cultivos de sangre que fueron incluidas y procesadas por sistema Bactec y Microscan, para determinar identificación y sensibilidad antimicrobiana. Se determinó la tendencia anual de la resistencia de cada organismo especificado a los diferentes antibióticos. Se obtuvo la diferencia porcentual (incremento o decremento comparando la frecuencia de resistencia al inicio y al final del estudio. RESULTADOS: Se detectaron 2 071 cultivos positivos. Se recuperaron Gram negativos en 59.7% de las muestras, Gram positivos en 35.7% y levaduras en 4.6%. Escherichia coli fue el principal germen identificado (18.6%, seguido de S. epidermidis (12.7% y Klebsiella spp (9%. Durante el periodo de estudio la sensibilidad se mantuvo estable y por arriba de 88% (excepto para Pseudomonas aeruginosa. La sensibilidad de ciprofloxacina para E. coli se encontró alrededor de 50%. Amikacina presentó mayor sensibilidad que gentamicina. Staphylococcus aureus presentó una sensibilidad a oxacilina de 96% y a vancomicina de 100%. S.epidermidis de 14% a oxacilina y de 98.6% a vancomicina. No se encontraron cepas de enterococo resistente a vancomicina. Todas las cepas de S. pneumoniae fueron sensibles a penicilina. CONCLUSIONES: Se considera que los patrones de resistencia encontrados en este hospital son el resultado del control en el uso de antimicrobianos, del programa de vigilancia de infecciones nosocomiales y de la utilización de terapia combinada en todos los pacientes con bacteremia.OBJECTIVE: To describe the patterns of antimicrobial resistance organisms isolated in blood cultures from patients detected in a tertiary level of care, teaching

  11. 高校建立管控型的财务共享服务中心模式的探讨--基于运用浪潮GS管理软件%Discussion on the Establishment of Management and Control Mode of Fi-nancial Shared Service Center in Colleges and Universities---Based on the Use of GS Management Software of Inspur

    Institute of Scientific and Technical Information of China (English)

    侯昌恕

    2015-01-01

    In November 2014, the Ministry of Finance issued Guidance on the Comprehensively Promoting the Construction of Management Accounting System (Accounting [2014] No. 27), which is not only the need of promoting upgrades of transfor-mation of economy of our country, but also the important measure for deepening the strategy of invigorating the country through accounting. It contributes to promoting the modernization of national governance systems and governance capacity and points out the important direction of accounting reform and development in our country. The development of management ac-counting in our country is relatively lagging behind. Colleges and universities, as the implementation units of management ac-counting, should strengthen budget management and cost control. On the base of learning useful cases of management account-ing work, we should choose the establishment of the“Internet +”management accounting information system according to the universities’situation. For instance, we can reform business processes by establishing financial shared center, build up system platform, design information system and business process solutions, achieve the integration of business and finance and realize the conjunction of accounting and budget management (i.e. embedded). Furthermore, we should provide more powerful support for the development of university by solving the problem of deviation from the budget and business and promoting working lev-el on accounting.%2014年11月,财政部《关于全面推进管理会计体系建设的指导意见》(财会【2014】27号),不仅是推动我国经济转型升级的需要,也是深入推进会计强国战略的重要举措,助力推进国家治理体系和治理能力现代化,指出了我国会计改革与发展的重要方向。我国管理会计发展相对滞后,高等学校做为管理会计的实施单位,应强化预算管理和成本控制,在对管理会计工作的有益案例进行

  12. Blood glucose control in diabetes patients seen in primary health care centers Controle glicêmico em pacientes diabéticos atendidos em centros de atenção primária à saúde

    Directory of Open Access Journals (Sweden)

    Maria Cecília F Assunção

    2005-04-01

    Full Text Available OBJECTIVE: To identify factors associated to poor glycemic control among diabetic patients seen at primary health care centers. METHODS: A cross-sectional study was carried out in a sample of 372 diabetic patients attending 32 primary health care centers in southern Brazil. Data on three hierarchical levels of health unit infrastructure, medical care and patient characteristics were collected. RESULTS: The frequency of poor glycemic control was 50.5%. Multivariate analysis (multilevel method showed that patients with body mass indexes below 27 kg/m², patients on oral hypoglycemic agents or insulin, and patients diagnosed as diabetic over five years prior to the interview were more likely to present poor glycemic control when compared to their counterparts. CONCLUSIONS: Given the hierarchical data structuring, all associations found suggest that factors associated to hyperglycemia are related to patient-level characteristics.OBJETIVO: Identificar fatores associados à falta de controle glicêmico em pacientes diabéticos atendidos em centros de atenção primária à saúde. MÉTODOS: Estudo transversal em amostra de 372 pacientes diabéticos atendidos nos 32 centros de atenção primária de uma cidade do sul do Brasil. Foram coletados dados ordenados em três níveis hierárquicos: estrutura das unidades de saúde, características do processo do cuidado médico e pacientes diabéticos. RESULTADOS: A freqüência de falta de controle glicêmico foi de 50,5%. A análise multivariada (método multinível mostrou que pacientes com Índice de Massa Corporal abaixo de 27 kg/m², em tratamento medicamentoso e com mais de cinco anos de diagnóstico de diabetes, tiveram maior probabilidade de apresentar hiperglicemia quando comparados a seus pares. CONCLUSÕES: Considerando a estrutura hierárquica dos dados, todas as associações encontradas sugerem que os fatores associados à hiperglicemia são relacionados a características dos pacientes.

  13. Blood Glucose Levels

    Directory of Open Access Journals (Sweden)

    Carlos Estela

    2011-01-01

    Full Text Available The purpose of this study was to establish a mathematical model which can be used to estimate glucose levels in the blood over time. The equations governing this process were manipulated with the use of techniques such as separation of variables and integration of first order differential equations, which resulted in a function that described the glucose concentration in terms of time. This function was then plotted, which allowed us to find when glucose concentration was at its highest. The model was then used to analyze two cases where the maximum glucose level could not exceed a certain level while the amount of carbohydrates and glycemic index were varied, independently.

  14. The level of endotoxins in hemodialysis water and dialysate in Lithuanian hemodialysis centers.

    Science.gov (United States)

    Skarupskienė, Inga; Bumblytė, Inga Arūnė; Tamošaitis, Donatas; Venterienė, Jūratė; Kuzminskis, Vytautas

    2010-01-01

    The composition and quality of the dialysis fluid play an important role in the modulation of dialysis-related complications. During hemodialysis, patient's blood has a contact with dialysate through a semipermeable membrane. Bacterial endotoxins can pass through the membrane pores into the patient's blood and cause a silent chronic microinflammation. The aim of this study was to determine the level of endotoxins in hemodialysis water and dialysate in Lithuanian hemodialysis centers. Dialysis water (n=50) and dialysate (n=50) were collected from 91% (n=50) of all hemodialysis centers. The presence of bacterial endotoxins was evaluated using a sensitive Limulus amebocyte lysate test, which detects intact lipopolysaccharides. The level of endotoxins was lower than 0.25 EU/mL in 43 (86%) dialysis water samples and in 46 (92%) dialysate samples, and complied with the recommendations of the European Pharmacopoeia and the European Best Practice Guidelines for pure dialysis fluid. The dialysate of 39 (78%) Lithuanian hemodialysis centers complied with the definition of an ultrapure dialysis fluid. The water and dialysate were of insufficient quality in 14% and in 8% of Lithuanian hemodialysis centers, respectively, and this could be improved by the establishment of routine investigation of endotoxins.

  15. Low Blood Glucose (Hypoglycemia)

    Science.gov (United States)

    ... Disease, & Other Dental Problems Diabetes & Sexual & Urologic Problems Low Blood Glucose (Hypoglycemia) What is hypoglycemia? Hypoglycemia, also called low blood glucose or low blood sugar, occurs when ...

  16. 建立我国HIV阳转血浆盘并评价HIV酶免血筛试剂窗口期%Evaluation of HIV diagnosis kits used for blood screening with NIFDC-established HIV-1 seroconver-sion panels

    Institute of Scientific and Technical Information of China (English)

    黄维金; 宋爱京; 许四宏; 王佑春

    2016-01-01

    目的:建立我国HIV系列阳转血清盘并用其评价HIV酶免血筛诊断试剂的窗口期。方法收集HIV感染者的系列血清,利用Western blot确认试剂、HIV抗原定量检测试剂、核酸定量检测试剂等检测系列样品,RT-PCR的方法扩增HIV env序列并测序和分型,以确认HIV感染。对国内外5种第四代和14种第三代酶免HIV血液筛查诊断试剂的检测窗口期进行评价。结果共收集确认8套HIV感染者的阳转系列血浆,AE亚型6套,B亚型1套,未分型1套,共含有36份样品。用HIV系列阳转血清盘评价发现四代抗原抗体联合检测试剂较三代抗体检测试剂具有更早的窗口期检测能力,前者评分9.4分,后者3.6分,差异具有统计学意义(t=8.547,P<0.01);部分国产四代试剂质量已经达到进口试剂的水平;核酸试剂的窗口期检测能力高于酶免试剂,在3套血清盘中至少提高2周以上;确认试剂的灵敏度低于血筛试剂的灵敏度;4/5四代试剂在检测感染早期样品时会出现检测信号值/界值( S/CO)下降的情况,存在第二窗口期漏检风险。结论本研究建立了8套我国的HIV系列阳转血清盘,评价发现我国HIV血液筛查酶免诊断试剂窗口期检测能力存在差异。%Objective To establish HIV-1 seroconversion panels with the samples collected by National Institutes for Food and Drug Control ( NIFDC) and to evaluate the window periods of HIV enzyme immunoassay ( EIA) diagnostic kits used for blood screening with them. Methods Serum specimens were collected from different plasma donation stations in China. All suspected HIV infection specimens were screened for HIV by using the nucleic acid amplification testing (NAT), Western blot confirmatory assay and P24 quantitative detection assay. The HIV env gene sequences were amplified by RT-PCR for further confirmation of HIV infection. The PCR products were sequenced and genotyped. The confirmed seroconver-sion panels were used to

  17. Blood hero: An application for encouraging the blood donation by applying gamification.

    Science.gov (United States)

    Domingos, Daniela C L; Lima, Luis F S G; Messias, Thiago F; Feijo, Jose V L; Diniz, Anthony A R; Soares, Heliana B

    2016-08-01

    There is a strong need for actions to supply the blood demand in the World. Based on this fact, it was designed an application, named `Blood Hero', by applying the `gamification' concept, which allows users to be rewarded by social acts related to the blood donation. It takes advantage of the application of mobile devices, implementing a specific social network, to attract and retain blood donators. This application makes possible an interaction between users and blood centers, and is being tested aiming at evaluating its acceptance and impact in bloodstocks.

  18. Establishment of an in vitro blood-brain barrier model by co-culturing rat brain microvascular endothelial cells,pericytes and astrocytes%大鼠脑微血管内皮细胞与周细胞、星形胶质细胞共培养建立体外血脑屏障模型

    Institute of Scientific and Technical Information of China (English)

    查雨锋; 傅晓钟; 张顺; 罗敏; 欧瑜; 董永喜; 王爱民; 王永林

    2015-01-01

    目的:应用原代培养的大鼠脑微血管内皮细胞(brain-microvessel endothelial cells,BMECs )与脑微血管周细胞(brain-microvessel pericytes,BMPC )、星形胶质细胞(astro-cytes,AS)共培养建立可模拟在体状态的体外血脑屏障(blood-brain barrier,BBB)模型。方法原代分离、纯化和培养大鼠BMECs、BMPC和AS,通过细胞形态学和免疫细胞化学染色方法鉴定原代培养的细胞,应用Millicell细胞培养插(孔径0.4μm)建立5种不同类型的体外BBB模型,经跨内皮电阻值(transendothelial electrical resistance,TEER)、荧光素钠通透性(sodium fluorescent,Na-FLU )、碱性磷酸酶(AKP)和γ-谷氨酰转肽酶(γ-GT1)的表达测定以及阳性药在体内和体外BBB通透量的相似性,比较评价其屏障功能。结果原代培养的BMECs呈典型的铺路卵石样结构,BMPC胞体较大且呈分枝状,AS 有细长突触,胞质较浅;免疫细胞化学染色证实原代细胞为目标细胞;BMECs与BMPC、AS共培养后TEER值可达(478±25)Ω·cm2,Na-FLU 的表观渗透系数为[(8.23±0.78)×10-6]cm·s-1,AKP和γ-GT1表达分别为(6.90±0.27)金氏单位· g-1 Pro,(4.39±0.32)μg·g-1 Pro;阳性药在体外BBB的表观渗透系数(apparent permeability coefficient,Papp )与在体数据具有较好的相关性(R2=0.92)。结论原代培养的大鼠BMECs与BMPC、AS共培养建立的体外BBB模型在形态、结构及屏障功能方面具备BBB的基本特征,为研究BBB的生理学、病理学以及筛选化合物提供了一种有用工具。%Aim To establish in vitro blood-brain barrier (BBB) model with characteristics of simulation of in vivo BBB by primi-tive co-culture of brain-microvessel endothelial cells (BMECs) with brain-microvessel pericytes (BMPC)and astrocytes (AS). Methods BMECs,BMPC and AS from SD rats were primitively isolated,purified and cultured,and then

  19. 自外周血记忆B细胞体外活化和分化抗原特异性浆细胞的方法研究%Establishment of activation and differentiation of memory B cells into antigen-specific secreting cells from peripheral blood mononuclear cells in vitro

    Institute of Scientific and Technical Information of China (English)

    毕冬梅; 韩晓建; 石佳宁; 刘晔; 金艾顺

    2015-01-01

    Objective To isolate antigen specific antibody-secreting cells (plasma cells) for development of antibody drug,we established efficient methods for the activation and differentiation of memory B cells into plasma cells in human peripheral blood lymphocytes (PBMCs) in vitro.Methods PBMCs were isolated from peripheral blood of two healthy donors received hepatitis B vaccine (named Z and L,vaccination time for 3 years and 25 years,respectively.).We actived and induced PBMCs by adding cytokines (IL-2 and IL-4) and TLR activators (CpG or R848) for 6 days.Secreted antibodies in the culture supernatans were measured by enzyme-linked immunosorbent assay (ELISA).Antibody secreting cells (ASCs) were detected by enzyme-linked immuno spot assay (ELISPOT).Results IgG concentrations in group C treated with CpG DNA 2006 combined with anti-CD40 antibody and IL-2 and in group R treated with R848 combined with IL-2 were 80.87 ng/mL and 85.97 ng/mL,respectively.These IgG levels were significantly higher copmpared with that in control group (t =23.318,t =60.639,both P < 0.05).The results showed that group C and R were efficiently actived,and the group R was significantly more than the group C.Both activation methods could induce B cell differentiation into plasma cells in vitro.Further,to analyze whether antigen specific plasma cells could be induced using the established motheds,we activated memory B cells in PBMCs vaccinated with hepatitis B vaccine.We detected HBsAg specific IgG secreting cells at different cell densities (104 to 105 cells/culture),the results showed that the group R was significantly more than the control group(t =5.031,t =11.561,both P < 0.05).Conclusion We established the optimal method for B cell activation in vitro.This method could efficiently induce activation and differentiation of memory B cells from PBMCs into antigen-specific plasma cells.%目的 建立自人外周血淋巴细胞(PBMCs)中的记忆B细胞活化和分化特异性抗体分泌细胞(

  20. Hausdorff centered measure of certain linear Cantor sets

    Institute of Scientific and Technical Information of China (English)

    PENG Li; WU Min

    2005-01-01

    In this paper, we study the Hausdorff centered measure of certain linear Cantor sets. We establish the relationship between the Hausdorff centered measure of this set and the maximum centered density of the corresponding self-similar measure. From this relationship, the Hausdorff centered measure of certain sets is obtained. In particular, we consider the linear iterated function system consisting of three maps with the same contraction ratios. Under some technical restrictions, we determine the exact Hausdorff centered measure of its attractor.

  1. 77 FR 29667 - Blood Products Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2012-05-18

    ... No. FDA-2012-N-0001] Blood Products Advisory Committee; Notice of Meeting AGENCY: Food and Drug... public. Name of Committee: Blood Products Advisory Committee. General Function of the Committee: To..., Office of Blood Research and Review, Center for Biologics Evaluation and Research, FDA. FDA intends...

  2. 78 FR 38351 - Blood Products Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2013-06-26

    ... HUMAN SERVICES Food and Drug Administration Blood Products Advisory Committee; Notice of Meeting AGENCY... will be closed to the public. Name of Committee: Blood Products Advisory Committee. General Function of..., Office of Blood Research and Review, Center for Biologics Evaluation and Research, FDA. FDA intends...

  3. Children's cancer centers

    Science.gov (United States)

    Pediatric cancer center; Pediatric oncology center; Comprehensive cancer center ... Treating childhood cancer is not the same as treating adult cancer. The cancers are different. So are the treatments and the ...

  4. Blood, Soy Milk, and Vitality: The Wartime Origins of Blood Banking in China, 1943-45.

    Science.gov (United States)

    Soon, Wayne

    2016-01-01

    This article examines the multiple meanings of blood transfusion and banking in modern China through the history of the first Chinese blood bank, established by the Overseas Chinese in 1943 to solicit blood for the war effort. Through investigating the attitudes of Chinese soldiers and civilians toward the blood bank, this article argues for the multiplicity of motivations underpinning society's attitudes toward blood banking and donation. Cultural notions of blood were an important but not the sole factor in their consideration. Ideas of nationalism and altruism played a role too. What eventually turned out to be most effective for most donors was the promise of eggs and soy milk for blood. Its economic value in the context of wartime scarcity was enough for many to abandon opposition to blood banking. By drawing attention to socioeconomic concerns in biomedical practices, this article provides an alternative examination of blood banking in modern societies.

  5. Blood safety in the world updated

    Institute of Scientific and Technical Information of China (English)

    Silvano Wandel

    2010-01-01

    @@ Blood safety is of paramount importance in any medical context, given that it represents one of the most impor-tant supportive procedures in medicine. Nearly all medical fields that lead with very critical patients will depend on blood products as part of supporting medical strategies (both clinical and surgical). Thus, it is im-portant that every country in the world relies on a well established national blood program.

  6. Discussion on the Necessity of Xuzhou Rubber Processing Engineering Research Center Established Research and Development%徐州市橡胶加工工程技术研究中心成立的必要性与研究开发探讨

    Institute of Scientific and Technical Information of China (English)

    王晓辉; 高敏; 邵晨露; 蔡可迎; 韩强

    2015-01-01

    Xuzhou City Rubber Processing Engineering Technology Research Center, Xuzhou Institute of Technology Chemical Engineering Institute to build, the goal is to nano TiO2 filling modified high performance rubber for research and development. The main direction of the research is the development and application of nano TiO2 filled with modified rubber technology, differentiation and high added value of rubber products, to meet the needs of the market, and to transform the results into quality products, to market, social services. The main projects include: nano TiO2surface treatment technology, nano TiO2 at room temperature curing silicone rubber technology, nano TiO2 changed to growth and development of antibacterial rubber arithmetic alienation of rubber products. In short, the establishment of scientific and technological achievements into productive forces, to shorten the production cycle, to provide new technology products for local enterprises to provide basic technical support for the introduction, digestion and absorption of foreign advanced technology, the development of Xuzhou Institute of technology and the industry to make due contribution.%徐州市橡胶加工工程技术研究中心由徐州工程学院化学化工学院筹建,目标是对纳米TiO2填充改性的高性能橡胶进行研究与开发.中心研究的主要方向为纳米TiO2填充改性橡胶技术、差异化和高附加值橡胶制品的开发及应用,适应市场的环保需求,并将成果转化为优质产品,推向市场,为社会服务.当前主要进行的项目包括有:纳米TiO2表面处理技术、纳米TiO2改性室温固化硅橡胶技术、纳米TiO2增和抗菌橡胶等差异化橡胶制品的开发.总之中心的成立可切实加强科技成果向生产力转化环节,缩短成果转化的周期,为本地企业提供高新技术产品的研究开发,为引进、消化和吸收国外先进技术提供基本技术支撑,对徐州工程学院和本行业的发展做出应有的贡献.

  7. Drug Establishments Current Registration Site

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Drug Establishments Current Registration Site (DECRS) is a database of current information submitted by drug firms to register establishments (facilities) which...

  8. Southern California Particle Center

    Data.gov (United States)

    Federal Laboratory Consortium — At the Southern California Particle Center, center researchers will investigate the underlying mechanisms that produce the health effects associated with exposure to...

  9. Womens Business Center

    Data.gov (United States)

    Small Business Administration — Women's Business Centers (WBCs) represent a national network of nearly 100 educational centers throughout the United States and its territories, which are designed...

  10. Blood Clotting and Pregnancy

    Medline Plus

    Full Text Available ... Initiative Research Programs and Awards View all Blood Current Issue First Edition Abstracts Blood Advances A peer- ... Get email updates View all meetings Publications Blood Current Issue First Edition Abstracts Blood Advances A peer- ...

  11. Hypertension (High Blood Pressure)

    Science.gov (United States)

    ... Surgery? A Week of Healthy Breakfasts Shyness Hypertension (High Blood Pressure) KidsHealth > For Teens > Hypertension (High Blood Pressure) Print ... rest temperature diet emotions posture medicines Why Is High Blood Pressure Bad? High blood pressure means a person's heart ...

  12. White Blood Cell Count

    Science.gov (United States)

    ... limited. Home Visit Global Sites Search Help? White Blood Cell Count Share this page: Was this page helpful? ... Count; Leukocyte Count; White Count Formal name: White Blood Cell Count Related tests: Complete Blood Count , Blood Smear , ...

  13. Lead levels - blood

    Science.gov (United States)

    Blood lead levels ... A blood sample is needed. Most of the time blood is drawn from a vein located on the inside ... may be used to puncture the skin. The blood collects in a small glass tube called a ...

  14. Blood donation before surgery

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000367.htm Blood donation before surgery To use the sharing features on ... described here. Blood From the Public (Volunteer Blood Donation) The most common source of blood given during ...

  15. Blood Clotting and Pregnancy

    Medline Plus

    Full Text Available ... infection) back to top How are Blood Clots in Pregnant Women Treated? Typically, blood clots are treated ... history of blood clots or blood clotting disorders in your family. Remain active, with your doctor's approval. ...

  16. High Blood Cholesterol

    Science.gov (United States)

    ... version of this page please turn Javascript on. High Blood Cholesterol What is High Blood Cholesterol? What is Cholesterol? Cholesterol is a ... heart disease. If Your Blood Cholesterol Is Too High Too much cholesterol in your blood is called ...

  17. Low Blood Pressure

    Science.gov (United States)

    ... a problem. Sometimes blood pressure that is too low can also cause problems. Blood pressure is the ... reading is 90/60 or lower, you have low blood pressure. Some people have low blood pressure ...

  18. Blood Transfusion (For Parents)

    Science.gov (United States)

    ... Old Feeding Your 1- to 2-Year-Old Blood Transfusions KidsHealth > For Parents > Blood Transfusions A A ... and help put your child at ease. About Blood Transfusions Blood is like the body's transportation system. ...

  19. Swiprosin-1/EFhd2 limits germinal center responses and humoral type 2 immunity.

    Science.gov (United States)

    Brachs, Sebastian; Turqueti-Neves, Adriana; Stein, Merle; Reimer, Dorothea; Brachvogel, Bent; Bösl, Michael; Winkler, Thomas; Voehringer, David; Jäck, Hans-Martin; Mielenz, Dirk

    2014-11-01

    Activated B cells are selected for in germinal centers by regulation of their apoptosis. The Ca2+ -binding cytoskeletal adaptor protein Swiprosin-1/EFhd2 (EFhd2) can promote apoptosis in activated B cells. We therefore hypothesized that EFhd2 might limit humoral immunity by repressing both the germinal center reaction and the expected enhancement of immune responses in the absence of EFhd2. Here, we established EFhd2(-/-) mice on a C57BL/6 background, which revealed normal B- and T-cell development, basal Ab levels, and T-cell independent type 1, and T-cell independent type 2 responses. However, T cell-dependent immunization with sheep red blood cells and infection with the helminth Nippostrongylus brasiliensis (N.b) increased production of antibodies of multiple isotypes, as well as germinal center formation in EFhd2(-/-) mice. In addition, serum IgE levels and numbers of IgE+ plasma cells were strongly increased in EFhd2(-/-) mice, both after primary as well as after secondary N.b infection. Finally, mixed bone marrow chimeras unraveled an EFhd2-dependent B cell-intrinsic contribution to increased IgE plasma cell numbers in N.b-infected mice. Hence, we established a role for EFhd2 as a negative regulator of germinal center-dependent humoral type 2 immunity, with implications for the generation of IgE.

  20. [Comparative analysis of semiotic shifts, established by LCS of blood plasma from random samples of studied subjects from the zone of the Chernobyl accident, "Ural Radiation Trace", and collaborators from St. Petersburg Institute of Nuclear Physics of the Russian Academy of Sciences].

    Science.gov (United States)

    Ternovoĭ, K S; Selezneva, T N; Akleev, A V; Pashkov, I A; Noskin, L A; Klopov, N V; Noskin, V A; Starodub, N F

    1998-01-01

    Using the developed "semiotic" classifier of laser correlation spectra of blood plasma the authors have carried out the verification of organism states of patients from the zone of Chernobyl accident, "Ural radiation trace" and collaborators from Sanct-Petersbourg Institute of Nuclear Physics. An analysis of results obtained using accidental selections which differed as to the character of radiation injury evidences for high informativeness of "semiotic" classifier of laser correlation spectra of blood plasma.

  1. Characterization of Transition to Turbulence for Blood in a Straight Pipe Under Steady Flow Conditions.

    Science.gov (United States)

    Biswas, Dipankar; Casey, David M; Crowder, Douglas C; Steinman, David A; Yun, Yang H; Loth, Francis

    2016-07-01

    Blood is a complex fluid that, among other things, has been established to behave as a shear thinning, non-Newtonian fluid when exposed to low shear rates (SR). Many hemodynamic investigations use a Newtonian fluid to represent blood when the flow field of study has relatively high SR (>200 s-1). Shear thinning fluids have been shown to exhibit differences in transition to turbulence (TT) compared to that of Newtonian fluids. Incorrect prediction of the transition point in a simulation could result in erroneous hemodynamic force predictions. The goal of the present study was to compare velocity profiles near TT of whole blood and Newtonian blood analogs in a straight rigid pipe with a diameter 6.35 mm under steady flow conditions. Rheology was measured for six samples of whole porcine blood and three samples of a Newtonian fluid, and the results show blood acts as a shear thinning non-Newtonian fluid. Measurements also revealed that blood viscosity at SR = 200 s-1 is significantly larger than at SR = 1000 s-1 (13.8%, p measure velocity profiles for blood and Newtonian samples at different flow rates to produce Reynolds numbers (Re) ranging from 1000 to 3300 (based on viscosity at SR = 1000 s-1). Two mathematically defined methods, based on the velocity profile shape change and turbulent kinetic energy (TKE), were used to detect TT. Results show similar parabolic velocity profiles for both blood and the Newtonian fluid for Re blood and Newtonian fluid velocity profiles for larger Re. The Newtonian fluid had blunt-like velocity profiles starting at Re = 2403 ± 8 which indicated transition. In contrast, blood did not show this velocity profile change until Re = 2871 ± 104. The Newtonian fluid had large velocity fluctuations (root mean square (RMS) > 20%) with a maximum TKE near the pipe center at Re = 2316 ± 34 which indicated transition. In contrast, blood results showed the maximum TKE at Re = 2806

  2. Student Success Center Toolkit

    Science.gov (United States)

    Jobs For the Future, 2014

    2014-01-01

    "Student Success Center Toolkit" is a compilation of materials organized to assist Student Success Center directors as they staff, launch, operate, and sustain Centers. The toolkit features materials created and used by existing Centers, such as staffing and budgeting templates, launch materials, sample meeting agendas, and fundraising…

  3. Taiyuan Satellite Launch Center

    Institute of Scientific and Technical Information of China (English)

    LiuJie

    2004-01-01

    There are three major space launch bases in China, the Jiuquan Satellite Launch Center,the Taiyuan Satellite Launch Center and the Xichang Satellite Launch Center. All the three launch centers are located in sparsely populated areas where the terrain is even and the field of vision is broad. Security, transport conditions and the influence of the axial rotation

  4. The Pittsburgh Poison Center profile of an American poison information center.

    Science.gov (United States)

    Krenzelok, Edward P

    2005-01-01

    The Pittsburgh Poison Center (PPC), a department of Children's Hospital of Pittsburgh, was established in 1971 to provide emergency poison information to the residents of western Pennsylvania, especially the children. The PPC provides comprehensive poison information center services to the lay public and to medical professionals, poison prevention education, professional education and specialized services to the business and industry sector and governmental agencies.

  5. O papel do usuário na organização do setor de coleta de sangue do Hemonúcleo de Apucarana, Paraná, Brasil The role of the user in the organization of the blood collection of the blood center of Apucarana, Paraná, Brazil

    Directory of Open Access Journals (Sweden)

    Leonardo Di Colli

    2009-04-01

    Full Text Available O Hemonúcleo de Apucarana faz parte da rede pública de bancos de sangue do estado do Paraná e tem como finalidade fornecer hemocomponentes com qualidade aos hospitais a ele conveniados. Com a proposta de atingir as metas do Ministério da Saúde em aumentar a quantidade de doadores espontâneos, o serviço tem se preocupado em buscar subsídios para melhora do processo de trabalho a fim de que este possa favorecer os objetivos de seu plano diretor. Para avaliar este processo, tornou-se necessário elaborar um instrumento de avaliação que possibilitasse identificar a percepção do doador em relação às diferentes etapas do processo de doação, bem como as áreas de insatisfação que se refletem em impedimentos para o retorno espontâneo deste doador. Este trabalho tem, portanto, o objetivo de demonstrar a satisfação dos doadores de sangue em relação às atividades executadas pelo Hemepar-Apucarana. Foram avaliadas questões como: orientações recebidas, horário de atendimento, ambiente físico (limpeza, agradabilidade e cortesia e equipe de trabalho. Todos os dados obtidos foram registrados num banco de dados e tabulados pela planilha Excel do Windows. Os dados determinados para avaliação foram classificados em ruim, regular, bom e ótimo, calculados em percentuais dispostos em tabelas elaboradas para sua visualização. Como resultado observou-se melhora da satisfação do doador em relação ao atendimento médico (p=0,038 e diminuição da satisfação em relação aos equipamentos e vestuário dos funcionários (p=0,012. Os demais ítens não apresentaram diferenças estatisticamente significantes entre os dois períodos avaliados.The hemocenter of the city of Apucarana, PR, Brazil, is part of Paraná State's Network of Blood Banks. Its purpose is to provide member hospitals with high-quality hemo-components. Proposing to fulfill the Brazilian Health Ministry's goals to increase the amount of first-time donors, Hemepar

  6. 14 CFR 25.27 - Center of gravity limits.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Center of gravity limits. 25.27 Section 25... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Flight General § 25.27 Center of gravity limits. The extreme forward and the extreme aft center of gravity limitations must be established for each...

  7. 20 CFR 638.808 - Center financial management and reporting.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Center financial management and reporting... § 638.808 Center financial management and reporting. The Job Corps Director shall establish procedures to ensure that each center operator and each subcontractor maintain a financial management...

  8. COMPUTATIONAL SCIENCE CENTER

    Energy Technology Data Exchange (ETDEWEB)

    DAVENPORT, J.

    2006-11-01

    Computational Science is an integral component of Brookhaven's multi science mission, and is a reflection of the increased role of computation across all of science. Brookhaven currently has major efforts in data storage and analysis for the Relativistic Heavy Ion Collider (RHIC) and the ATLAS detector at CERN, and in quantum chromodynamics. The Laboratory is host for the QCDOC machines (quantum chromodynamics on a chip), 10 teraflop/s computers which boast 12,288 processors each. There are two here, one for the Riken/BNL Research Center and the other supported by DOE for the US Lattice Gauge Community and other scientific users. A 100 teraflop/s supercomputer will be installed at Brookhaven in the coming year, managed jointly by Brookhaven and Stony Brook, and funded by a grant from New York State. This machine will be used for computational science across Brookhaven's entire research program, and also by researchers at Stony Brook and across New York State. With Stony Brook, Brookhaven has formed the New York Center for Computational Science (NYCCS) as a focal point for interdisciplinary computational science, which is closely linked to Brookhaven's Computational Science Center (CSC). The CSC has established a strong program in computational science, with an emphasis on nanoscale electronic structure and molecular dynamics, accelerator design, computational fluid dynamics, medical imaging, parallel computing and numerical algorithms. We have been an active participant in DOES SciDAC program (Scientific Discovery through Advanced Computing). We are also planning a major expansion in computational biology in keeping with Laboratory initiatives. Additional laboratory initiatives with a dependence on a high level of computation include the development of hydrodynamics models for the interpretation of RHIC data, computational models for the atmospheric transport of aerosols, and models for combustion and for energy utilization. The CSC was formed to

  9. Effect of spiritual therapy on blood pressure, anxiety and quality of life in patients with high blood pressure

    OpenAIRE

    2014-01-01

    Background: High blood pressure is the most important risk factor of cardiovascular diseases. This study was conducted to evaluate the efficacy of spiritual therapy on blood pressure, anxiety and quality of life in patients with high blood pressure. Method: This study was quasi-experimentalwith apretest-posttest and control group design. The sample consisted of 30 patients with high blood pressure refering to Kangavar Healthcare center that were selected through convenience sampling and...

  10. Center of excellence in laser medicine. Progress report

    Energy Technology Data Exchange (ETDEWEB)

    Parrish, J.A.

    1992-09-01

    Achievements during the first six months of funding to prepare for a Center of Excellence in biomedical laser development include limited specific research projects within the Center`s three broad interest areas, and program development to establish the Center and its activities. Progress in the three interest areas -- new medical laser systems development, optical diagnostics, and photosensitization, is reported. Feasibility studies and prototype development were emphasized, to enhance establishing a substantial Center through future support. Specific projects are an optimized laser-catheter system for reversal of vasospasm; optical detection of major skin burn depth and cancers using fluorescent drugs, and photosensitization of vascular tissues. In addition, an interdepartmental Laser Center was established at MGH to enhance collaborations and institutional committment to the Center of Excellence. Competitive postdoctoral research fellowships, with provision for matching funds from other departments, have been announced.

  11. Report on Ten Years' Experience of Premarital Hemoglobinopathy Screening at a Center in Antalya, Southern Turkey.

    Science.gov (United States)

    Canatan, Duran; Delibas, Serpil

    2016-08-01

    Thalassemia and hemoglobinopathies are a major public health problem in Turkey. Hemoglobinopathy prevention programs (HPPs) were started in 33 provinces situated in Thrace, Marmara, Aegean, Mediterranean and South Eastern regions of Turkey in 2003. A premarital hemoglobinopathy test is mandatory and free of charge in this program. According to the Ministry of Health reports, 46 first level hemoglobinopathy diagnostic centers were established for premarital tests. Within the last 10 years, approximately 79.0% of married individuals per year were screened by the centers. While the percentage of premarital screening tests was 30.0% of all couples in 2003, it reached 86.0% in 2013. The number of newborn with thalassemia and hemoglobinopathies were 272 in 2002 and dropped to 25 in 2013. There has been a 90.0% reduction in affected births. Our hemoglobinopathy diagnostic center was established in 2003 and licensed by the Ministry of Health in 2004. We studied a total of 89,981 blood samples from premarital tests for 10 years and the incidence of β- and α-thalassemia (β- and α-thal) trait was found to be 6.57 and 3.56%, respectively. The distribution of the most common abnormal hemoglobins (Hbs) was: Hb S (HBB: c.20A > T) (0.31%), Hb D-Los Angeles (HBB: c.364G > C) (0.15%), Hb G-Coushatta (HBB: c.68A > C) (0.06%) and Hb E (HBB: c.79G > A) (0.02%). A total of 60 couples, both carrying β-thal trait, were directed to the prenatal diagnosis (PND) center in 10 years. The premarital hemoglobinopathy screening program is running successfully at our center and other centers in Turkey.

  12. A CASE OF RARE BLOOD GROUP IN OBSTETRIC EMERGENCY

    Directory of Open Access Journals (Sweden)

    Sudha

    2014-08-01

    Full Text Available We present a rare case of an A2B +ve blood group with obstetric hemorrhage in mild hypovolemic shock with DIC. An emergency request for blood transfusion confounded the blood bank officer as the patient’s blood was seemingly incompatible with all ABO blood groups. Further investigation revealed the patient’s blood group to be a rare subtype of the A group known as A2+veB. This article highlights the need to be aware of such rare subgroups, especially in tertiary referral centers, where unbooked Obstetric emergencies are encountered on a regular basis, so life-saving measures can be appropriately taken.

  13. [Blood transfusion and supply chain management safety].

    Science.gov (United States)

    Quaranta, Jean-François; Caldani, Cyril; Cabaud, Jean-Jacques; Chavarin, Patricia; Rochette-Eribon, Sandrine

    2015-02-01

    The level of safety attained in blood transfusion now makes this a discipline better managed care activities. This was achieved both by scientific advances and policy decisions regulating and supervising the activity, as well as by the quality system, which we recall that affects the entire organizational structure, responsibilities, procedures, processes and resources in place to achieve quality management. So, an effective quality system provides a framework within which activities are established, performed in a quality-focused way and continuously monitored to improve outcomes. This system quality has to irrigate all the actors of the transfusion, just as much the establishments of blood transfusion than the health establishments.

  14. Diagnóstico de imunofenótipos de síndromes linfoproliferativas crônicas por citometria de fluxo na Fundação HEMOPA Diagnosis of immunophenotyping of chronic lymphoproliferative syndromes by flow cytometry at HEMOPA blood center

    Directory of Open Access Journals (Sweden)

    Lacy Cardoso de Brito Junior

    2011-12-01

    Full Text Available INTRODUÇÃO: As síndromes linfoproliferativas formam um grupo heterogêneo de neoplasias malignas com diferentes comportamentos clínicos, fatores patológicos e características epidemiológicas e podem ter seu diagnóstico geral com base na morfologia das células linfoides observadas no sangue periférico. OBJETIVO: Testar a factibilidade diagnóstica do método de imunofenotipagem por citometria de fluxo para síndromes linfoproliferativas a partir da definição de um painel mínimo de anticorpos. MATERIAL E MÉTODOS: Participaram 47 pacientes para diagnóstico diferencial dos subtipos de síndromes linfoproliferativas por citometria de fluxo, no período de julho de 2008 a julho de 2010, atendidos na Fundação HEMOPA. RESULTADOS: A mediana de idade dos pacientes foi de 68 anos, não houve diferença estatística entre os sexos e o subtipo de síndromes linfoproliferativas mais frequente foi a leucemia linfoide crônica/linfoma linfocítico de pequenas células B. CONCLUSÃO: O método de imunofenotipagem por citometria de fluxo, ao lado da morfologia, de amostras de sangue periférico mostrou-se uma metodologia auxiliar, segura, rápida, factível e não invasiva para o diagnóstico de síndromes linfoproliferativas crônicas a partir do painel de anticorpos sugerido.INTRODUCTION: Lymphoproliferative syndromes comprise a heterogeneous group of malignant neoplasias with different clinical behaviors, pathological factors and epidemiological characteristics, whose diagnosis may be based on lymphoid cell morphology observed in peripheral blood. OBJECTIVE: To test the diagnostic feasibility of immunophenotyping by flow cytometry for lymphoproliferative syndromes through the definition of minimal antibody panel. MATERIAL AND METHODS: During the period of July 2008 to July 2010, 47 patients from HEMOPA blood center participated in this study for differential diagnosis of lymphoproliferative syndromes subtypes by flow cytometry. RESULTS: The

  15. Antifungal prophylaxis in stem cell transplantation centers in Turkey

    Directory of Open Access Journals (Sweden)

    Hamdi Akan

    2011-12-01

    Full Text Available Objective: This study aimed to determine the current state of antifungal prophylaxis in Turkish stem cell transplantation (SCT centers. Materials and Methods: The were 38 active stem cell transplantation centers in Turkey, 28 of which were registered with the European Group for Blood and Marrow Transplantation (EBMT. Survey questionnaires were sent to the 28 EBMT centers in an effort to collect data on antifungal prophylaxis in different settings. In all, 24 of the centers completed the survey; 1 of the 24 centers was excluded from the study, as it was under construction at the time and was not performing transplantation.Results: In all, 15 (65% of the 23 centers were adult SCT centers, 7 (31% were pediatric SCT centers, and 1 center treated both adult and pediatric patients. All centers (23/23 performed both allogeneic and autologous transplants, 20 centers performed non-myeloablative transplants, 8 performed cord blood transplants, and 7 performed unrelated transplants. Primary antifungal prophylaxis was used at all 23 centers during allogeneic transplants, whereas 18 of the 23 centers used it during every autologous transplant and 2 of the 23 centers used it during autologous transplants on a per case basis. The most common drug used for prophylaxis was fluconazole (F (21/23, followed by itraconazole (I (3/23, amphotericin-B (2/23, and posaconazole (1/23. Among the 23 centers, 3 reported that for allogenic transplants they changed the antifungal prophylactic in cases of graft versus host disease (GVHD, and 12 of the 23 centers reported that they changed the antifungal prophylactic in case of nearby construction. All 23 centers performed secondary prophylaxis. Conclusion: Antifungal prophylaxis for hematopoetic SCT patients was the standard protocol in the 23 centers included in the study, usually with such azoles as F. The introduction of posaconazole in Turkey and the potential approval of voriconazole for antifungal prophylaxis will

  16. NASA(Field Center Based) Technology Commercialization Centers

    Science.gov (United States)

    1995-01-01

    Under the direction of the IC(sup 2) Institute, the Johnson Technology Commercialization Center has met or exceeded all planned milestones and metrics during the first two and a half years of the NTCC program. The Center has established itself as an agent for technology transfer and economic development in- the Clear Lake community, and is positioned to continue as a stand-alone operation. This report presents data on the experimental JTCC program, including all objective measures tracked over its duration. While the metrics are all positive, the data indicates a shortage of NASA technologies with strong commercial potential, barriers to the identification and transfer of technologies which may have potential, and small financial return to NASA via royalty-bearing licenses. The Center has not yet reached the goal of self-sufficiency based on rental income, and remains dependent on NASA funding. The most important issues raised by the report are the need for broader and deeper community participation in the Center, technology sourcing beyond JSC, and the form of future funding which will be appropriate.

  17. Chinese Women Lawyers Society Established

    Institute of Scientific and Technical Information of China (English)

    1994-01-01

    ON November 12, 1993, the Chinese Women Lawyers Society was established in Beijing. The more than 10,000 women lawyers in the country were excited to have their own organization. Xu Weihua, secretary-general of the society and a lawyer working in the All-China Women’s Federation, said: "The society’s establishment will promote the participation of

  18. Patient Workload Profile: National Naval Medical Center (NNMC), Bethesda, MD.

    Science.gov (United States)

    1980-06-01

    Special Chemistry) * Microbiology (including Bacteriology, Mycology , Serology, and Virology) * Hematology 0 Blood Bank (including Blood Donor Center...fish, poultry , meats, milk, bread, canned goods, etc.); labor, overhead, and expendable non-food items are excluded. The current food budget is

  19. Asynchronicity of facial blood perfusion in migraine.

    Directory of Open Access Journals (Sweden)

    Nina Zaproudina

    Full Text Available Asymmetrical changes in blood perfusion and asynchronous blood supply to head tissues likely contribute to migraine pathophysiology. Imaging was widely used in order to understand hemodynamic variations in migraine. However, mapping of blood pulsations in the face of migraineurs has not been performed so far. We used the Blood Pulsation Imaging (BPI technique, which was recently developed in our group, to establish whether 2D-imaging of blood pulsations parameters can reveal new biomarkers of migraine. BPI characteristics were measured in migraineurs during the attack-free interval and compared to healthy subjects with and without a family history of migraine. We found a novel phenomenon of transverse waves of facial blood perfusion in migraineurs in contrast to healthy subjects who showed synchronous blood delivery to both sides of the face. Moreover, the amplitude of blood pulsations was symmetrically distributed over the face of healthy subjects, but asymmetrically in migraineurs and subjects with a family history of migraine. In the migraine patients we found a remarkable correlation between the side of unilateral headache and the direction of the blood perfusion wave. Our data suggest that migraine is associated with lateralization of blood perfusion and asynchronous blood pulsations in the facial area, which could be due to essential dysfunction of the autonomic vascular control in the face. These findings may further enhance our understanding of migraine pathophysiology and suggest new easily available biomarkers of this pathology.

  20. Asynchronicity of facial blood perfusion in migraine.

    Science.gov (United States)

    Zaproudina, Nina; Teplov, Victor; Nippolainen, Ervin; Lipponen, Jukka A; Kamshilin, Alexei A; Närhi, Matti; Karjalainen, Pasi A; Giniatullin, Rashid

    2013-01-01

    Asymmetrical changes in blood perfusion and asynchronous blood supply to head tissues likely contribute to migraine pathophysiology. Imaging was widely used in order to understand hemodynamic variations in migraine. However, mapping of blood pulsations in the face of migraineurs has not been performed so far. We used the Blood Pulsation Imaging (BPI) technique, which was recently developed in our group, to establish whether 2D-imaging of blood pulsations parameters can reveal new biomarkers of migraine. BPI characteristics were measured in migraineurs during the attack-free interval and compared to healthy subjects with and without a family history of migraine. We found a novel phenomenon of transverse waves of facial blood perfusion in migraineurs in contrast to healthy subjects who showed synchronous blood delivery to both sides of the face. Moreover, the amplitude of blood pulsations was symmetrically distributed over the face of healthy subjects, but asymmetrically in migraineurs and subjects with a family history of migraine. In the migraine patients we found a remarkable correlation between the side of unilateral headache and the direction of the blood perfusion wave. Our data suggest that migraine is associated with lateralization of blood perfusion and asynchronous blood pulsations in the facial area, which could be due to essential dysfunction of the autonomic vascular control in the face. These findings may further enhance our understanding of migraine pathophysiology and suggest new easily available biomarkers of this pathology.

  1. Blood vessels, circulation and blood pressure.

    Science.gov (United States)

    Hendry, Charles; Farley, Alistair; McLafferty, Ella

    This article, which forms part of the life sciences series, describes the vessels of the body's blood and lymphatic circulatory systems. Blood pressure and its regulatory systems are examined. The causes and management of hypertension are also explored. It is important that nurses and other healthcare professionals understand the various mechanisms involved in the regulation of blood pressure to prevent high blood pressure or ameliorate its damaging consequences.

  2. Blood donor: nursing care plan

    Directory of Open Access Journals (Sweden)

    Marco Antonio Zapata Sampedro

    2008-11-01

    Full Text Available The standardized nursing care plan can be used as a means through which the nurse will assess and identify the particular needs of the blood donor.To draw up the care plan, we have conducted the evaluation on the basis of the Marjory Gordon’s functional health patterns.The more prevailing diagnosis according to the NANDA taxonomy have been identified, results have been established according to the NOC (Nursing Outcomes Classification taxonomy, and nursing interventions have been suggested according to the NIC (Nursing Interventions Classification taxonomy. Also, certain potential complications, which are infrequent, must be observed and controlled in the blood donation process. Our main aim with this article has been to offer to professionals resources that grant to the caring activity scientific rigor, professional recognition and an unique and valid tool to evaluate the assistance with the best levels of quality for the blood donor.

  3. American Studies Center:An Introduction

    Institute of Scientific and Technical Information of China (English)

    Shu; HONG

    2013-01-01

    <正>The year 2012 was remarkable in the history of American Studies at Sichuan University.First,it marked the 28thAnniversary of the founding of the American Studies Center,which had its official debut in May,1984,coinciding with the establishment of the US Consulate General in Chengdu.U.S.Vice President George Bush was present at the Inauguration Ceremony of the American Studies Center,and

  4. Blood stain pattern analysis.

    Science.gov (United States)

    Peschel, O; Kunz, S N; Rothschild, M A; Mützel, E

    2011-09-01

    Bloodstain pattern analysis (BPA) refers to the collection, categorization and interpretation of the shape and distribution of bloodstains connected with a crime. These kinds of stains occur in a considerable proportion of homicide cases. They offer extensive information and are an important part of a functional, medically and scientifically based reconstruction of a crime. The following groups of patterns can essentially be distinguished: dripped and splashed blood, projected blood, impact patterns, cast-off stains, expirated and transferred bloodstains. A highly qualified analysis can help to estimate facts concerning the location, quality and intensity of an external force. A sequence of events may be recognized, and detailed questions connected with the reconstruction of the crime might be answered. In some cases, BPA helps to distinguish between accident, homicide and suicide or to identify bloodstains originating from a perpetrator. BPA is based on systematic training, a visit to the crime scene or alternatively good photographic documentation, and an understanding and knowledge of autopsy findings or statements made by the perpetrator and/or victim. A BPA working group has been established within the German Society of Legal Medicine aiming to put the knowledge and practical applications of this subdiscipline of forensic science on a wider basis.

  5. Hydrologic Engineering Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Hydrologic Engineering Center (HEC), an organization within the Institute for Water Resources, is the designated Center of Expertise for the U.S. Army Corps of...

  6. NIH Clinical Centers

    Data.gov (United States)

    Federal Laboratory Consortium — The NIH Clinical Center consists of two main facilities: The Mark O. Hatfield Clinical Research Center, which opened in 2005, houses inpatient units, day hospitals,...

  7. Center for Women Veterans

    Science.gov (United States)

    ... Aid & Attendance & Housebound Caregivers Community Living Centers (CLC) Community Nursing Homes Domiciliaries (Please contact your local VA Medical Center) Homemaker & Home Health Aid Care Hospice and Palliative Care State Veterans ...

  8. BKG Data Center

    Science.gov (United States)

    Thorandt, Volkmar; Wojdziak, Reiner

    2013-01-01

    This report summarizes the activities and background information of the IVS Data Center for the year 2012. Included is information about functions, structure, technical equipment, and staff members of the BKG Data Center.

  9. Day Care Centers

    Data.gov (United States)

    Department of Homeland Security — This database contains locations of day care centers for 50 states and Washington D.C. and Puerto Rico. The dataset only includes center based day care locations...

  10. Poison Control Centers

    Science.gov (United States)

    ... 1222 immediately. Name State American Association of Poison Control Centers Address AAPCC Central Office NOT A POISON ... not for emergency use. Arkansas ASPCA Animal Poison Control Center Address 1717 S. Philo Road, Suite 36 Urbana, ...

  11. Center of Attention.

    Science.gov (United States)

    Coffey, J. Steven; Wood-Steed, Ruth

    2001-01-01

    Illustrates how college and university student centers are becoming the institution's marketing tools. Explores how the Millennium Center at the University of Missouri in St. Louis exemplifies this new trend. (GR)

  12. RSW Cell Centered Grids

    Data.gov (United States)

    National Aeronautics and Space Administration — New cell centered grids are generated to complement the node-centered ones uploaded. Six tarballs containing the coarse, medium, and fine mixed-element and pure tet....

  13. MARYLAND ROBOTICS CENTER

    Data.gov (United States)

    Federal Laboratory Consortium — The Maryland Robotics Center is an interdisciplinary research center housed in the Institute for Systems Research (link is external)within the A. James Clark School...

  14. National Rehabilitation Information Center

    Science.gov (United States)

    ... including News and Notes) Welcome to the National Rehabilitation Information Center! We are conducting improvements to the ... experience. We apologize for any inconvenience The National Rehabilitation Information Center ( NARIC ) is the library of the ...

  15. MARYLAND ROBOTICS CENTER

    Data.gov (United States)

    Federal Laboratory Consortium — The Maryland Robotics Center is an interdisciplinary research center housed in the Institute for Systems Research (link is external) within the A. James Clark School...

  16. Automating the Media Center.

    Science.gov (United States)

    Holloway, Mary A.

    1988-01-01

    Discusses the need to develop more efficient information retrieval skills by the use of new technology. Lists four stages used in automating the media center. Describes North Carolina's pilot programs. Proposes benefits and looks at the media center's future. (MVL)

  17. Center for Functional Nanomaterials

    Data.gov (United States)

    Federal Laboratory Consortium — The Center for Functional Nanomaterials (CFN) explores the unique properties of materials and processes at the nanoscale. The CFN is a user-oriented research center...

  18. Blood Culture (For Parents)

    Science.gov (United States)

    ... Feeding Your 1- to 2-Year-Old Blood Culture KidsHealth > For Parents > Blood Culture Print A A ... adjust the treatment choice. Why Do a Blood Culture? During some illnesses, certain infection-causing bacteria and ...

  19. Coughing up blood

    Science.gov (United States)

    ... gastrointestinal tract. Blood that comes up with a cough often looks bubbly because it is mixed with ... conditions, diseases, and medical tests may make you cough up blood. These include: Blood clot in the ...

  20. High Blood Pressure

    Science.gov (United States)

    ... normal blood pressure 140/90 or higher is high blood pressure Between 120 and 139 for the top number, ... prehypertension. Prehypertension means you may end up with high blood pressure, unless you take steps to prevent it. High ...

  1. High Blood Pressure (Hypertension)

    Science.gov (United States)

    ... Print Page Text Size: A A A Listen High Blood Pressure (Hypertension) Nearly 1 in 3 American adults has ... weight. How Will I Know if I Have High Blood Pressure? High blood pressure is a silent problem — you ...

  2. Ketones blood test

    Science.gov (United States)

    ... Ketones - serum; Nitroprusside test; Ketone bodies - serum; Ketones - blood ... A blood sample is needed. ... When the needle is inserted to draw blood, some people feel slight ... there may be some throbbing or a slight bruise. This soon ...

  3. Magnesium blood test

    Science.gov (United States)

    Magnesium - blood ... A blood sample is needed. ... When the needle is inserted to draw blood, some people feel slight pain. Others feel a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon ...

  4. CEA blood test

    Science.gov (United States)

    Carcinoembryonic antigen blood test ... A blood sample is needed . ... When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging sensation. Afterward, there may be some throbbing or a slight bruise. ...

  5. Glucagon blood test

    Science.gov (United States)

    ... type I - glucagon test; Hypoglycemia - glucagon test; Low blood sugar - glucagon test ... A blood sample is needed . ... When the needle is inserted to draw blood, some people feel ... Afterward, there may be some throbbing or a slight bruise. This ...

  6. Special Blood Donation Procedures

    Science.gov (United States)

    ... takes about 10 minutes. Double red blood cell donation In the so-called double red blood cell ... can be cured with apheresis. Directed or designated donation Family members or friends can donate blood specifically ...

  7. Home blood sugar testing

    Science.gov (United States)

    Diabetes - home glucose testing; Diabetes - home blood sugar testing ... Usual times to test your blood sugar are before meals and at bedtime. Your provider may ask you to check your blood sugar 2 hours after a meal. Ask ...

  8. High blood sugar

    Science.gov (United States)

    ... High blood glucose - self-care; Diabetes - high blood sugar ... Symptoms of high blood sugar can include: Being very thirsty or having a dry mouth Having blurry vision Having dry skin Feeling weak or tired ...

  9. Hyperglycemia (High Blood Glucose)

    Medline Plus

    Full Text Available ... Blood Pressure Physical Activity High Blood Glucose My Health Advisor Tools To Know Your Risk Alert Day ... DKA (Ketoacidosis) & Ketones Kidney Disease (Nephropathy) Gastroparesis Mental Health Step On Up Treatment & Care Blood Glucose Testing ...

  10. Blood and Diversity

    Science.gov (United States)

    ... patient diversity. For example, U-negative and Duffy-negative blood types are unique to the African-American community. ... most common blood type and because type O negative blood, in particular, is the universal type needed for ...

  11. Blood Pressure Test

    Science.gov (United States)

    ... an online personal health record or blood pressure tracker, for example. This gives you the option of ... lower your blood pressure. Exercise regularly. Regular physical activity can help lower your blood pressure and keep ...

  12. Blood Clotting and Pregnancy

    Medline Plus

    Full Text Available ... First Edition Abstracts Blood Advances A peer-reviewed, online only, open access journal with a unique focus ... help: Results of Clinical Studies Published in Blood Search Blood , the official journal of ASH, for the ...

  13. Symptoms of Blood Disorders

    Science.gov (United States)

    ... leg (causing most often swelling, redness, and/or warmth of the leg or shortness of breath) Petechiae ( ... Disorders Symptoms of Blood Disorders Medical History and Physical Examination for Blood Disorders Laboratory Tests for Blood ...

  14. Low Blood Pressure (Hypotension)

    Science.gov (United States)

    ... and rises sharply on waking. Blood pressure: How low can you go? What's considered low blood pressure ... even life-threatening disorders. Conditions that can cause low blood pressure Some medical conditions can cause low ...

  15. Red blood cell production

    Science.gov (United States)

    ... to one part of the body or another. Red blood cells are an important element of blood. Their job ... is carried to and eliminated by the lungs. Red blood cells are formed in the red bone marrow of ...

  16. Exposing the Data Center

    OpenAIRE

    Sergejev, Ivan

    2014-01-01

    Given the rapid growth in the importance of the Internet, data centers - the buildings that store information on the web - are quickly becoming the most critical infrastructural objects in the world. However, so far they have received very little, if any, architectural attention. This thesis proclaims data centers to be the 'churches' of the digital society and proposes a new type of a publicly accessible data center. The thesis starts with a brief overview of the history of data centers ...

  17. The Fermilab Particle Astrophysics Center

    Energy Technology Data Exchange (ETDEWEB)

    2004-11-01

    The Particle Astrophysics Center was established in fall of 2004. Fermilab director Michael S. Witherell has named Fermilab cosmologist Edward ''Rocky'' Kolb as its first director. The Center will function as an intellectual focus for particle astrophysics at Fermilab, bringing together the Theoretical and Experimental Astrophysics Groups. It also encompasses existing astrophysics projects, including the Sloan Digital Sky Survey, the Cryogenic Dark Matter Search, and the Pierre Auger Cosmic Ray Observatory, as well as proposed projects, including the SuperNova Acceleration Probe to study dark energy as part of the Joint Dark Energy Mission, and the ground-based Dark Energy Survey aimed at measuring the dark energy equation of state.

  18. Data center cooling method

    Energy Technology Data Exchange (ETDEWEB)

    Chainer, Timothy J.; Dang, Hien P.; Parida, Pritish R.; Schultz, Mark D.; Sharma, Arun

    2015-08-11

    A method aspect for removing heat from a data center may use liquid coolant cooled without vapor compression refrigeration on a liquid cooled information technology equipment rack. The method may also include regulating liquid coolant flow to the data center through a range of liquid coolant flow values with a controller-apparatus based upon information technology equipment temperature threshold of the data center.

  19. The Clerical Establishment in Iran

    Science.gov (United States)

    1989-06-01

    clerics as teachers of religion and related subjects in Iran’s public educational system. A.~ d 22 various seminaries in Qom, Mashad , Tabriz, Shiraz...under wax. One copy of the new document was again handed to Meshkini and the other hand delivered to Mashad to be deposited in the tomb of Imam Reza...urban centers as Qom, Mashad , Yazd, and Ker- man seem to be their primary centers of support. Hoseyn Ali Montazeri was born in 1922 in the township of

  20. Qualitative analysis fingertip patterns in ABO blood group

    Directory of Open Access Journals (Sweden)

    S. V. KShirsagar

    2013-05-01

    Full Text Available The inheritance of the dermatoglyphic patterns is polygenic. The genetic basis of the blood group is well established. The correlation between the dermatoglyphic patterns and the ABO blood group is studied by some workers in different populations. In the present study, the correlation between dermatoglyphics and ABO blood group is studied in the Marathwada Region of Maharashtra. The qualitative data included fingertip patterns and three indices. It was observed that, the Arch pattern is more common in blood group O both in male and female. Ulnar loop is most common in the blood group AB. Simple whorl and double loop whorl patterns are less frequent in blood group AB. Accidentals were not recorded in blood group A while blood group O show highest percentage of accidentals. Dankmeijer’s index was highest in blood group AB and lowest in blood group B.

  1. Hemochromatosis: the new blood donor.

    Science.gov (United States)

    Leitman, Susan F

    2013-01-01

    Hereditary hemochromatosis (HH) due to homozygosity for the C282Y mutation in the HFE gene is a common inherited iron overload disorder in whites of northern European descent. Hepcidin deficiency, the hallmark of the disorder, leads to dysregulated intestinal iron absorption and progressive iron deposition in the liver, heart, skin, endocrine glands, and joints. Survival is normal if organ damage is prevented by early institution of phlebotomy therapy. HH arthropathy is the symptom most affecting quality of life and can be debilitating. Genotype screening in large population studies has shown that the clinical penetrance of C282Y homozygosity is highly variable and can be very low, with up to 50% of women and 20% of men showing a silent phenotype. Targeted population screening for the HFE C282Y mutation is not recommended at present, but might be reconsidered as a cost-effective approach to management if counseling and care were better organized and standardized. Referral of patients to the blood center for phlebotomy therapy and use of HH donor blood for transfusion standardizes treatment, minimizes treatment costs, and may benefit society as a whole. Physician practices should be amended such that HH subjects are more frequently referred to the blood center for therapy.

  2. American Studies Center:An Introduction

    Institute of Scientific and Technical Information of China (English)

    Shu; HONG

    2013-01-01

    The year 2012 was remarkable in the history of American Studies at Sichuan University.First,it marked the 28thAnniversary of the founding of the American Studies Center,which had its official debut in May,1984,coinciding with the establishment of the US Consulate General in Chengdu.U.S.Vice President George Bush was present at the Inauguration Ceremony of the American Studies Center,and afterwards gave an important talk to the university faculty and students.The past 28years have witnessed the steady development of this Center.In June,2012,the

  3. 48 CFR 1536.602-2 - Establishment of evaluation boards.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Establishment of evaluation boards. 1536.602-2 Section 1536.602-2 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION... Service Center Manager (SCM) is delegated the authority to appoint either one or two additional...

  4. 慢性心力衰竭心气虚兼血瘀水肿证大鼠模型的建立与整合判定%Establishment of Chronic Heart Failure Rat Model of Xin-qi Deficiency Complicated Blood Stasis and Edema Syndrome and Judgment of Diagnosis Information Integration

    Institute of Scientific and Technical Information of China (English)

    林家茂; 郭伟星; 王营; 刘颖; 李亚茹; 李珩; 周杰

    2014-01-01

    血瘀水肿证的SD大鼠模型.%Objective To establish and evaluate chronic heart failure (CHF) rat model of Xin-qi deficiency complicated blood stasis and edema syndrome (XQD-BSES).Methods Totally 40 SD rats were randomly divided into the normal control group (Control),the propylthiouracil (PTU) group,the adriamycin (ADR),and the ADR + PTU group.Normal saline was used as equivalent solvent of each group.Rats in the Control group were intragastrically and intraperitoneally injected with normal saline.Rats in the PTU group were intragastrically injected with PTU suspension and intraperitoneally injected with normal saline.Rats in the ADR group were intragastrically injected with ADR solution and intraperitoneally injected with normal saline.And rats in the ADR + PTU group were intragastrically injected with PTU suspension and intraperitoneally injected with ADR solution.The dose of PTU was 0.2% of daily forage weight,once daily.The dose of ADR was 3.5 mg/kg,once per week.The modeling lasted for 6 weeks.Left ventricular ejection fraction (LVEF),left ventricular fraction shortening (LVFS),brain natriuretic peptide (BNP),heart rate (HR),respiratory rate (RR),urine output,ear temperature,exhaustive swimming test (EST),Tri-iodothyronine (T3),tetra-iodothyronine (T4),thyroid stimulating hormone (TSH) as well as heart,lung,liver weight indices and their pathological sections were integrated and compared.Results Compared with the Control group,LVEF,LVFS,BNP,HR,RR,heart,lung,liver weight indices,urine output,ear temperature,EST,and T3,T4,and TSH changed significantly in the ADR group,the PTU group,and the ADR + PTU group with statistical significance (P <0.05),and pathological changes of heart failure occurred in pathological sections of heart,lung,and liver.Compared with the ADR group,LVEF,LVFS,BNP,and lung,liver weight indices,urine output,ear temperature,T3,T4,and TSH changed significantly in the ADR + PTU group with statistical significance (P < 0.05),and

  5. How to establish a company

    OpenAIRE

    Konečný, Viktor

    2008-01-01

    This diploma thesis is focused on a franchising business establishment, particularly on the business establishment of a fictive coffe house which could become a well known franchising concept on the Czech market. Primary advantage of franchise compared to the other types of business cooperation is mainly risk reduction for the investor (franchisee) who obtains proven model of the business. For the franchisor the franchise means an easier way how to widen his business without taking higher lab...

  6. 75 FR 36060 - Notice of Request for Extension of Approval of an Information Collection; Blood and Tissue...

    Science.gov (United States)

    2010-06-24

    ... Collection; Blood and Tissue Collection at Slaughtering and Rendering Establishments AGENCY: Animal and Plant... collection associated with regulations for blood and tissue collection at slaughtering and rendering... FURTHER INFORMATION CONTACT: For information on regulations for blood and tissue collection...

  7. Cord blood stem cell banking and transplantation.

    Science.gov (United States)

    Dhot, P S; Nair, V; Swarup, D; Sirohi, D; Ganguli, P

    2003-12-01

    Stem cells have the ability to divide for indefinite periods in culture and to give rise to specialized cells. Cord blood as a source of hematopoietic stem cells (HSC) has several advantages as it is easily available, involves non-invasive collection procedure and is better tolerated across the HLA barrier. Since the first cord blood transplant in 1988, over 2500 cord blood HSC transplants have been done world wide. Since then, the advantages of cord blood as a source of hematopietic stem cells for transplantation have become clear. Firstly, the proliferative capacity of HSC in cord blood is superior to that of cells in bone marrow or blood from adults. A 100 ml unit of cord blood contains 1/10th the number of nucleated cells and progenitor cells (CD34+ cells) present in 1000 ml of bone marrow, but because they proliferate rapidly, the stem cell in a single unit of cord blood can reconstitute the entire haematopoietic system. Secondly, the use of cord blood reduces the risk of graft vs host disease. Cord Blood Stem Cell banks have been established in Europe and United States to supply HSC for related and unrelated donors. Currently, more than 65,000 units are available and more than 2500 patients have received transplants of cord blood. Results in children have clearly shown that the number of nucleated cells in the infused cord blood influences the speed of recovery of neutrophils and platelets after myeloablative chemotherapy. The optimal dose is about 2 x 10(7) nucleated cells/kg of body weight. The present study was carried out for collection, separation, enumeration and cryopreservation of cord blood HSC and establishing a Cord Blood HSC Bank. 172 samples of cord blood HSC were collected after delivery of infant prior to expulsion of placenta. The average cord blood volume collected was 101.20 ml. Mononuclear cell count ranged from 7.36 to 25.6 x 10(7)/ml. Viability count of mononuclear cells was 98.1%. After 1 year of cryopreservation, the viability count on

  8. 地中海贫血患者来源外周血及脐带血细胞诱导式多能干细胞的建系和造血分化%Establishment of the thalassemia patient-specific induced pluripotent stem cells from peripheral and cord blood ;cells and its hematopoietic differentiation

    Institute of Scientific and Technical Information of China (English)

    曾敏慧; 蒋满波; 艳飞; 彭澄; 张滨; 蔡柳洪

    2015-01-01

    Objective To investigate the construction and hematopoietic differentiation of induced pluripotent stem cells ( iPSCs) from thalassemia patients .Methods Cord blood from artificial labored fetus with HbH disease (α-thalassemia) and peripheral blood from a case of heterozygote of β-thalassemia (genotype IVS-II-654/CD17) were obtained.The iPSCs were re-programed from mononuclear cells separated from obtained cord blood and peripheral blood . Hematopoietic stem cell differentiation was induced by OP 9 cell co-culture.The pluripotent markers of iPSCs were detec-ted by immunofluorescence and alkaline phosphatase staining , while embryoid bodies ( EBs) and teratoma forming experi-ments were used to detect the pluripotency .Results Pluripotent biomarkers , including Oct4, SSEA4, tra-1-60 and tra-1-81, and alkaline phosphatase , were positive on iPSCs.EBs were formed by suspended culture .Three germ layer cells were found in the teratoma test .The results of flow cytometry showed that CD 34+cells was 4.46%and 8.71%from cord blood and peripheral sources , respectively, after co-cultured with OP9 cells.Conclusion Cord blood and periph-eral blood MNCs of patients with αorβthalassemia, can be reprogrammed into iPSCs , and differentiated into hematopoi-etic stem cells.%目的:探讨地中海贫血(地贫)患者特异诱导式多能干细胞系( iPSCs)细胞模型的建立及造血分化能力。方法采集HbH病引产胎儿(α地贫)的脐带血、双重杂合子β地贫输血患者(基因型为IVS-Ⅱ-654/CD17)外周血各1例,分离单核细胞后进行短期培养,核转染再程序化为iPSCs,检测iPSCs未分化状态和多能性标志物。 iPSCs与OP9细胞共培养向造血干细胞诱导分化,进行吉姆萨染色检查和流式细胞术检测造血干细胞的分化结果。结果地贫患者iPSCs表达干细胞多能性标志物Oct4、SSEA4、Tra-1-60、Tra-1-81,碱式磷酸酶染色阳性,悬浮培养可以形成类

  9. Teaming Up Against High Blood Pressure

    Centers for Disease Control (CDC) Podcasts

    2012-09-04

    This podcast is based on the September 2012 CDC Vital Signs report. A team-based approach by patients, health care systems, and health care providers is one of the best ways to treat uncontrolled high blood pressure.  Created: 9/4/2012 by Centers for Disease Control and Prevention (CDC).   Date Released: 9/4/2012.

  10. 人外周血树突状细胞体外稳定培养方法的建立及与磁珠法的比较%Establishment of in vitro stable culture of human peripheral blood dendritic cells and its comparation with magnetic activated cell sorting

    Institute of Scientific and Technical Information of China (English)

    单骄宇; 刘弓伯; 吐尔洪江·吐尔逊; 张雪; 阿尔孜古丽·吐逊; 林仁勇; 温浩

    2010-01-01

    Objective To establish a economic and stable method to induce and culture dendritic cells (DCs) from peripheral blood of human being, and compare with the magnetic activated cell sorting. Methods Monocytes were isolated from health donors peripheral blood mononuclear cells(PBMC) by density gradient separation,cultured and compared with that of cells isolated by the magnetic activated cell sorting or adherent culture,respectively. PBMC were cultured with recombinant human granulocyte macrophage colony stimulating factor (rhGM-CSF) and recombinant human interleukin-4(rhIL-4) for 6 days to induce the growth of DCs. Morphological changes was observed under inverted microscope. Meanwhile, cell viability was tested at the 3rd, 5th, 6th day,respectively. The phenotypes, like CD14, CDla, HLA-DR were analyzed with flow cytometry after PBMC were adherent cultured for 1, 2, 5 h. After adding human recombinant cytokines, the phenotypes of acquired cells surface markers, CD14, CD1a, CD86, CD83 and HLA-DR would be detected and compared with flow cytometry. T cells proliferating activity was determined by allogeneic mixed lymphocyte reaction in vitro. Results After adherent culture for 2 h, the acquired DCs showed typical morphology. Cell viability was decreased at days 5th, 6th[(53.333 ±5.774)%,(38.333 ± 7.638)%] than that at day of 3rd[(68.667 ± 3.215)%, all P < 0.05] with the magnetic activated cell sorting, but with adherent culture method, the difference was not statistically significant (F = 0.737,P> 0.05) at days of 3rd, 5th, 6th[(92.667 ± 3.055)%,(94.000 ± 1.000)%,(94.667 ± 1.528)%]. Moreover,compared with the magnetic activated cell sorting, there were differences in cell viability of adherent culture method at days of 3rd, 5th, 6th(t = 9.374, 12.021,12.527, all P < 0.05). Before and after using the magnetic activated cell sorting, the expression of CD14 were (32.457 ± 12.351) %, (41.914 ± 14.858)%, respectively. The difference was not statistically

  11. Treating High Blood Pressure

    Science.gov (United States)

    About High Blood Pressure Many people in the United States die from high blood pressure. This condition usually does not cause symptoms. Most ... until it is too late. A person has high blood pressure when the blood pushes against Visit your doctor ...

  12. Hypertension (High Blood Pressure)

    Science.gov (United States)

    ... Loss Surgery? A Week of Healthy Breakfasts Shyness Hypertension (High Blood Pressure) KidsHealth > For Teens > Hypertension (High Blood Pressure) A ... rest temperature diet emotions posture medicines Why Is High Blood Pressure Bad? High blood pressure means a person's heart ...

  13. BUN - blood test

    Science.gov (United States)

    Blood urea nitrogen ... A blood sample is needed. Most of the time blood is drawn from a vein located on the inside ... Many medicines can interfere with blood test results. Your health ... if you need to stop taking any medicines before you have this ...

  14. Introduction to Iranian Blood Transfusion Organization and Blood Safety in Iran

    Directory of Open Access Journals (Sweden)

    H Abolghasemi

    2009-03-01

    Full Text Available "nCurrently, in Iran blood transfusion is an integral part of the national health system and blood donation is voluntary and non­remu­nerated and blood and its components may not be a source of profit. In 1974 and following establishment of Iranian Blood Transfusion Organization (IBTO all blood transfusion activities from donor recruitment to production of blood com­po­nents and delivery of blood and blood products were centralized. The activities of IBTO are followed the laws and regu­la­tions of Ministry of Health and criteria of Iran National Regulatory Authority. In order to meet the country's demand in 2007 IBTO collected about 1.7 millions units of blood from the population of 70 millions. In 1979 coincided with the Is­lamic revolution the number of  blood units collected throughout the country were 124,000 units or 3.4 unit per 1000 popu­la­tion whereas after about 30 years this increased to about 25 unit per 1000 population. With improving the pool of vol­un­tary donors, IBTO has been successful in excluding "family replacement" donation since 2007 and reached to 100% volun­tary and nonremunerated blood donation. Currently more than 92% of blood donors in Iran are male and contribution of fe­male in blood donation is less than 8%. Although all donated blood in Iran screened for HBsAg since 1974, screening of blood units for HIV and HCV started since 1989 and 1996, respectively. The frequency of HBV infection in blood do­nors showed a significant decline from 1.79% in 1998 to 0.4% in 2007. The overall frequency of HCV and HIV infection are 0.13% and 0.004% respectively.

  15. Requirements for blood and blood components intended for transfusion or for further manufacturing use. Final rule.

    Science.gov (United States)

    2015-05-22

    The Food and Drug Administration (FDA) is amending the regulations applicable to blood and blood components, including Source Plasma, to make the donor eligibility and testing requirements more consistent with current practices in the blood industry, to more closely align the regulations with current FDA recommendations, and to provide flexibility to accommodate advancing technology. In order to better assure the safety of the nation's blood supply and to help protect donor health, FDA is revising the requirements for blood establishments to test donors for infectious disease, and to determine that donors are eligible to donate and that donations are suitable for transfusion or further manufacture. FDA is also requiring establishments to evaluate donors for factors that may adversely affect the safety, purity, and potency of blood and blood components or the health of a donor during the donation process. Accordingly, these regulations establish requirements for donor education, donor history, and donor testing. These regulations also implement a flexible framework to help both FDA and industry to more effectively respond to new or emerging infectious agents that may affect blood product safety.

  16. Establishing operations and the mand.

    Science.gov (United States)

    Michael, J

    1988-01-01

    In Verbal Behavior Skinner identifies a small number of elementary verbal relations, one of which is the mand. Because its introduction is at first in terms of unlearned motivative variables, and because the mand's relation to prior controlling events is quite complex, its general significance has probably been underestimated. An extensive treatment of establishing operations, including the warning and the blocked-response conditioned establishing operations is provided, followed by a description of the mand in terms of such operations. The importance of the mand for language training programs is suggested, as well as the reasons why it is typically neglected in such programs.

  17. Acoustic comfort in eating establishments

    DEFF Research Database (Denmark)

    Svensson, David; Jeong, Cheol-Ho; Brunskog, Jonas

    2014-01-01

    The subjective concept of acoustic comfort in eating establishments has been investigated in this study. The goal was to develop a predictive model for the acoustic comfort, by means of simple objective parameters, while also examining which other subjective acoustic parameters could help explain...... the feeling of acoustic comfort. Through several layers of anal ysis, acoustic comfort was found to be rather complex, and could not be explained entirely by common subjective parameters such as annoyance, intelligibility or privacy. A predictive model for the mean acoustic comfort for an eating establishment...

  18. Association of ABO and Rh Blood Groups to Blood-Borne Infections among Blood Donors in Tehran-Iran

    Science.gov (United States)

    MOHAMMADALI, Fatemeh; POURFATHOLLAH, Aliakbar

    2014-01-01

    Abstract Background The aim of this study was to investigate the prevalence of hepatitis B, hepatitis C, HIV and syphilis infections in blood donors referred to Tehran Blood Transfusion Center (TBTC), and determine any association between blood groups and blood- borne infections between the years of 2005 and 2011. Methods This was a retrospective study conducted at TBTC. All of the donor serum samples were screened for HBV, HCV, HIV and syphilis by using third generation ELISA kits and RPR test. Initial reactive samples were tested in duplicate. Confirmatory tests were performed on all repeatedly reactive donations. Blood group was determined by forward and reverse blood grouping. The results were subjected to chi square analysis for determination of statistical difference between the values among different categories according to SPSS program. Results Overall, 2031451 donor serum samples were collected in 2005-2011. Totally, 10451 were positive test for HBV, HCV, HIV and syphilis. The overall seroprevalence of HBV, HCV, HIV, and syphilis was 0.39%, 0.11%, 0.005%, and 0.010%, respectively. Hepatitis B and HIV infections were significantly associated with blood group of donors (P 0.05). Conclusion Compared with neighboring countries and the international standards, prevalence of blood-borne infections is relatively low. PMID:25909065

  19. Association of ABO and Rh Blood Groups to Blood-Borne Infections among Blood Donors in Tehran-Iran.

    Directory of Open Access Journals (Sweden)

    Fatemeh Mohammadali

    2014-07-01

    Full Text Available The aim of this study was to investigate the prevalence of hepatitis B, hepatitis C, HIV and syphilis infections in blood donors referred to Tehran Blood Transfusion Center (TBTC, and determine any association between blood groups and blood- borne infections between the years of 2005 and 2011.This was a retrospective study conducted at TBTC. All of the donor serum samples were screened for HBV, HCV, HIV and syphilis by using third generation ELISA kits and RPR test. Initial reactive samples were tested in duplicate. Confirmatory tests were performed on all repeatedly reactive donations. Blood group was determined by forward and reverse blood grouping. The results were subjected to chi square analysis for determination of statistical difference between the values among different categories according to SPSS program.Overall, 2031451 donor serum samples were collected in 2005-2011. Totally, 10451 were positive test for HBV, HCV, HIV and syphilis. The overall seroprevalence of HBV, HCV, HIV, and syphilis was 0.39%, 0.11%, 0.005%, and 0.010%, respectively. Hepatitis B and HIV infections were significantly associated with blood group of donors (P 0.05.Compared with neighboring countries and the international standards, prevalence of blood-borne infections is relatively low.

  20. Blood lead levels and chronic blood loss

    Energy Technology Data Exchange (ETDEWEB)

    Manci, E.A.; Cabaniss, M.L.; Boerth, R.C.; Blackburn, W.R.

    1986-03-01

    Over 90% of lead in blood is bound to the erythrocytes. This high affinity of lead for red cells may mean that chronic blood loss is a significant means for excretion of lead. This study sought correlations between blood lead levels and clinical conditions involving chronic blood loss. During May, June and July, 146 patients with normal hematocrits and red cell indices were identified from the hospital and clinic populations. For each patient, age, race, sex and medical history were noted, and a whole blood sample was analyzed by flameless atomic absorption spectrophotometry. Age-and race-matched pairs showed a significant correlation of chronic blood loss with lead levels. Patients with the longest history of blood loss (menstruating women) had the lowest level (mean 6.13 ..mu..g/dl, range 3.6-10.3 ..mu..g/dl). Post-menopausal women had levels (7.29 ..mu..g/dl, 1.2-14 ..mu..g/dl) comparable to men with peptic ulcer disease, or colon carcinoma (7.31 ..mu..g/dl, 5.3-8.6 ..mu..g/dl). The highest levels were among men who had no history of bleeding problems (12.39 ..mu..g/dl, 2.08-39.35 ..mu..g/dl). Chronic blood loss may be a major factor responsible for sexual differences in blood lead levels. Since tissue deposition of environmental pollutants is implicated in diseases, menstruation may represent a survival advantage for women.

  1. NYIT Energy Information Center. A first report

    Energy Technology Data Exchange (ETDEWEB)

    Magat, G.

    1976-08-16

    The Energy Information Center was created to serve (1) the research and information dissemination purposes of the Center for Energy Policy and Reearch, and (2) the information outreach programs of the Energy Advisory Service established by the Center. The Center is primarily concerned with (a) energy conservation, (b) alternative energy sources, (c) energy usage, and (d) energy policy, and insofar as they relate to these matters, it is concerned secondarily with fossil energy, nuclear energy, and international energy developments. Accordingly, the Energy Information Center acquires materials in such fields as engineering, economics, and the political, social, and behavioral sciences. In addition to serving the research and information dissemination needs of the Center for Energy Policy and Research, the Energy Information Center also supports the Center's Energy Advisory Service outreach program in which information and technical assistance in the use of energy conserving techniques and equipment is made available to industrial and commercial organizations, public officials, homeowners, and the general public throughout the New York New Jersey, and Connecticut area.

  2. Plug Pulled on Chemistry Computer Center.

    Science.gov (United States)

    Robinson, Arthur L.

    1980-01-01

    Discusses the controversy surrounding the initial decision to establish, and the current decision to phase out, the National Resource for Computation in Chemistry (NRCC), a computational chemistry center jointly sponsored by the National Science Foundation and the Department of Energy. (CS)

  3. Increasing Counseling Center Utilization: Yeshiva University's Experience

    Science.gov (United States)

    Schwartz, Victor; Nissel, Chaim; Eisenberg, Daniel; Kay, Jerald; Brown, Joshua T.

    2012-01-01

    Yeshiva University established a counseling center during the 2004-2005 academic year. As a religiously based institution, the administration recognized that there would likely be significant impediments to utilization of on-campus mental health services as a result of negative attitudes about mental illness and its treatment--stigma. To combat…

  4. Transportation Technical Environmental Information Center index

    Energy Technology Data Exchange (ETDEWEB)

    Davidson, C.A.; Foley, J.T.

    1979-01-01

    In an effort to determine the environmental intensities to which energy materials in transit may be exposed, a ''Data Center'' of technical environmental information has been established by Sandia Laboratories, Division 5522, for the DOE Division of Environmental Control Technology. An index is presented which can be used to request data of interest.

  5. Test Control Center exhibit

    Science.gov (United States)

    2000-01-01

    Have you ever wondered how the engineers at John C. Stennis Space Center in Hancock County, Miss., test fire a Space Shuttle Main Engine? The Test Control Center exhibit at StenniSphere can answer your questions by simulating the test firing of a Space Shuttle Main Engine. A recreation of one of NASA's test control centers, the exhibit explains and portrays the 'shake, rattle and roar' that happens during a real test firing.

  6. Relativistic Guiding Center Equations

    Energy Technology Data Exchange (ETDEWEB)

    White, R. B. [PPPL; Gobbin, M. [Euratom-ENEA Association

    2014-10-01

    In toroidal fusion devices it is relatively easy that electrons achieve relativistic velocities, so to simulate runaway electrons and other high energy phenomena a nonrelativistic guiding center formalism is not sufficient. Relativistic guiding center equations including flute mode time dependent field perturbations are derived. The same variables as used in a previous nonrelativistic guiding center code are adopted, so that a straightforward modifications of those equations can produce a relativistic version.

  7. [The study on the establishment of acupuncture].

    Science.gov (United States)

    Jung, Woojin

    2011-12-31

    In ancient china, four famous literatures, Huang Di Nei Jing, Nan Jing, Ben Cao, Shang Han Lun appeared, which made the foundation of oriental medicine. Huang Di Nei Jing, the book of acupuncture, is the most essential literature among these four litertures. So the question asking the identity of oriental medicine can be turned into the question about the identity of acupuncture. The investigation into origin will not be the only way to study of identity but one of the most attractive means. So we can answer with the study of origin to the question about identity. Acupuncture is comprised of theories like jing mai, qi xue and technical factors like moxibustion, bian which is like present operating knife. To trace the origin of acupuncture, we must investigate not only technical factors but also theories. But it will be impossible to trace every theories underlying the acupuncture in this small thesis. This is the reason that I restricted my attention to the principle of preventive medicine, regimen. Before the excavation of Mawangdui, the belief that acupuncture started long ago before Han period had been generally accepted. But there was not any proof proving the presence of acupuncture in the excavated literatures representing the Han period medicine. This fact announced that we must draw the time of establishment of acupuncture back after the Mawangdui literature buried in B.C. 168. But we can find the proof of the presence of acupuncture just before B.C. 168 in Shiji written by Si Mi Qian. Through these facts and inferences that we got until now, we can reach a conclusion that acupuncture would have appeared around 190-176 when Chun Yu Yi was practicing as a doctor. As you know, in the Mawangdui literature, what was associated with jing mai was moxibustion. But at the same time, moxibustion was being used just as the experience medicine technique without theory. So the moxibustion would has been about to be associated with jing mai theory in Mawangdui period

  8. Effect of perioperative blood transfusions on long term graft outcomes in renal transplant patients.

    LENUS (Irish Health Repository)

    O'Brien, Frank J

    2012-06-01

    It is established that blood transfusions will promote sensitization to human leucocyte antigen (HLA) antigens, increase time spent waiting for transplantation and may lead to higher rates of rejection. Less is known about how perioperative blood transfusion influence patient and graft outcome. This study aims to establish if there is an association between perioperative blood transfusion and graft or patient survival.

  9. Great Lakes Science Center

    Data.gov (United States)

    Federal Laboratory Consortium — Since 1927, Great Lakes Science Center (GLSC) research has provided critical information for the sound management of Great Lakes fish populations and other important...

  10. Small Business Development Center

    Data.gov (United States)

    Small Business Administration — Small Business Development Centers (SBDCs) provide assistance to small businesses and aspiring entrepreneurs throughout the United States and its territories. SBDCs...

  11. Advanced Simulation Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Simulation Center consists of 10 individual facilities which provide missile and submunition hardware-in-the-loop simulation capabilities. The following...

  12. Environmental Modeling Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Environmental Modeling Center provides the computational tools to perform geostatistical analysis, to model ground water and atmospheric releases for comparison...

  13. Surgery center joint ventures.

    Science.gov (United States)

    Zasa, R J

    1999-01-01

    Surgery centers have been accepted as a cost effective, patient friendly vehicle for delivery of quality ambulatory care. Hospitals and physician groups also have made them the vehicles for coming together. Surgery centers allow hospitals and physicians to align incentives and share benefits. It is one of the few types of health care businesses physicians can own without anti-fraud and abuse violation. As a result, many surgery center ventures are now jointly owned by hospitals and physician groups. This article outlines common structures that have been used successfully to allow both to own and govern surgery centers.

  14. Test Control Center (TCC)

    Data.gov (United States)

    Federal Laboratory Consortium — The Test Control Center (TCC) provides a consolidated facility for planning, coordinating, controlling, monitoring, and analyzing distributed test events. ,The TCC...

  15. Data Center at NICT

    Science.gov (United States)

    Ichikawa, Ryuichi; Sekido, Mamoru

    2013-01-01

    The Data Center at the National Institute of Information and Communications Technology (NICT) archives and releases the databases and analysis results processed at the Correlator and the Analysis Center at NICT. Regular VLBI sessions of the Key Stone Project VLBI Network were the primary objective of the Data Center. These regular sessions continued until the end of November 2001. In addition to the Key Stone Project VLBI sessions, NICT has been conducting geodetic VLBI sessions for various purposes, and these data are also archived and released by the Data Center.

  16. Airline Operation Center Workstation

    Data.gov (United States)

    Department of Transportation — The Airline Operation Center Workstation (AOC Workstation) represents equipment available to users of the National Airspace system, outside of the FAA, that enables...

  17. Center for Deployment Psychology

    Data.gov (United States)

    Federal Laboratory Consortium — The Center for Deployment Psychology was developed to promote the education of psychologists and other behavioral health specialists about issues pertaining to the...

  18. Electron Microscopy Center (EMC)

    Data.gov (United States)

    Federal Laboratory Consortium — The Electron Microscopy Center (EMC) at Argonne National Laboratory develops and maintains unique capabilities for electron beam characterization and applies those...

  19. Audio Visual Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Audiovisual Services Center provides still photographic documentation with laboratory support, video documentation, video editing, video duplication, photo/video...

  20. Establishing Time for Professional Learning

    Science.gov (United States)

    Journal of Staff Development, 2013

    2013-01-01

    Time for collaborative learning is an essential resource for educators working to implement college- and career-ready standards. The pages in this article include tools from the workbook "Establishing Time for Professional Learning." The tools support a complete process to help educators effectively find and use time. The following…

  1. Women, Hypertension, and the Systolic Blood Pressure Intervention Trial.

    Science.gov (United States)

    Wenger, Nanette K; Ferdinand, Keith C; Bairey Merz, C Noel; Walsh, Mary Norine; Gulati, Martha; Pepine, Carl J

    2016-10-01

    Hypertension accounts for approximately 1 in 5 deaths in American women and is the major contributor to many comorbid conditions. Although blood pressure lowering reduces cardiovascular disease outcomes, considerable uncertainty remains on best management in women. Specifically, female blood pressure treatment goals have not been established, particularly among older and African American and Hispanic women, for whom hypertension prevalence, related adverse outcomes, and poor control rates are high. The Systolic Blood Pressure Intervention Trial (SPRINT) planned to clarify optimal blood pressure management in both sexes. Although confirming that a lower blood pressure goal is generally better, because female enrollment and event rates were low and follow-up shortened, outcomes differences in women were not statistically significant. Thus optimal blood pressure goals for women have not been established with the highest evidence. This review addresses SPRINT's significance and key remaining knowledge gaps in optimal blood pressure management to improve women's health.

  2. Red blood cell alloimmunization after blood transfusion

    NARCIS (Netherlands)

    Schonewille, Henk

    2008-01-01

    Current pretransfusion policy requires the patients’ serum to be tested for the presence of irregular red blood cell antibodies. In case of an antibody, red blood cells lacking the corresponding antigen are transfused after an antiglobulin crossmatch. The aim of the studies in this thesis is primari

  3. Funding Opportunity: Genomic Data Centers

    Science.gov (United States)

    Funding Opportunity CCG, Funding Opportunity Center for Cancer Genomics, CCG, Center for Cancer Genomics, CCG RFA, Center for cancer genomics rfa, genomic data analysis network, genomic data analysis network centers,

  4. Estudo comparativo entre o manejo da asma em uma unidade de referência da rede pública de Porto Alegre (RS e as proposições do III Consenso Brasileiro no Manejo da Asma Asthma management in a public referral center in Porto Alegre in comparison with the guidelines established in the III Brazilian Consensus on Asthma Management

    Directory of Open Access Journals (Sweden)

    Waldo Mattos

    2006-10-01

    Full Text Available OBJETIVO: Avaliar se as diretrizes do III Consenso Brasileiro no Manejo da Asma estão sendo aplicadas em uma população de asmáticos em um hospital de referência da rede pública de Porto Alegre (RS. MÉTODOS: Todos os pacientes adultos que iniciaram tratamento entre 1999 e 2002 foram avaliados. O tratamento recebido foi classificado em concordante ou discordante do Consenso. As características clínicas da asma e a freqüência do tratamento por especialista foram comparadas entre os grupos. RESULTADOS: Foram avaliados os prontuários de 357 pacientes, com média de idade de 41 anos, sendo 106 homens (29,7% e 251 mulheres (70,3%, 33 tabagistas (9,2%. O tratamento foi considerado discordante em 246 pacientes (70%, sendo que, neste grupo, houve ausência de tratamento com corticóide inalatório em pacientes com asma persistente em 174 deles (71%. Volume expiratório forçado no primeiro segundo normal, idade entre doze e dezoito anos e asma intermitente foram observados com maior freqüência entre os pacientes com tratamento concordante (p OBJECTIVE: To determine whether the guidelines put forth in the III Brazilian Consensus on Asthma Management are being applied in a population of asthma patients treated at a public hospital that is a referral center for asthma in the city of Porto Alegre, Brazil. METHODS: All adult asthma patients who began their treatment between 1999 and 2002 were evaluated. The treatment given was classified as consistent or inconsistent with the Consensus guidelines. The clinical features of asthma and the frequency of treatment provided by a specialist were compared between the two groups (those receiving guideline-consistent treatment and those receiving guideline-inconsistent treatment. RESULTS: The charts of 357 patients were evaluated. The study sample consisted of 106 males (29.9% and 251 females (70.3%. The mean age was 41 years, and 33 (9.2% of the patients were smokers. The treatment was considered

  5. Detecting phase singularities and rotor center trajectories based on the Hilbert transform of intraatrial electrograms in an atrial voxel model

    Directory of Open Access Journals (Sweden)

    Unger Laura Anna

    2015-09-01

    Full Text Available This work aimed at the detection of rotor centers within the atrial cavity during atrial fibrillation on the basis of phase singularities. A voxel based method was established which employs the Hilbert transform and the phase of unipolar electrograms. The method provides a 3D overview of phase singularities at the endocardial surface and within the blood volume. Mapping those phase singularities from the inside of the atria at the endocardium yielded rotor center trajectories. We discuss the results for an unstable and a more stable rotor. The side length of the areas covered by the trajectories varied from 1.5 mm to 10 mm. These results are important for cardiologists who target rotors with RF ablation in order to cure atrial fibrillation.

  6. Information Centers at NAL.

    Science.gov (United States)

    Frank, Robyn C.

    1989-01-01

    Descriptions of the 12 specialized information centers of the National Agricultural Library (NAL) include subject coverage, information services provided, information technologies used, and staffing. The development of the Rural Information Center, a joint venture between the Extension Service and NAL to provide information services to local…

  7. Assessing the Assessment Center.

    Science.gov (United States)

    LaRue, James

    1989-01-01

    Describes the historical use of assessment centers as staff development and promotional tools and their current use in personnel selection. The elements that constitute a true assessment center are outlined, and a discussion of the advantages and disadvantages for employers and applicants focuses on positions in library administration. (10…

  8. Handbook for Learning Centers.

    Science.gov (United States)

    Norwalk Board of Education, CT.

    The handbook for learning centers contains guidelines, forms, and supplementary information to be used with all children identified as having a learning disability, mild retardation, or sensory deprivation in the Norwalk, Connecticut public schools. It is stressed that the learning center should provide supportive services for at least 35 minutes…

  9. Relative Lyapunov Center Bifurcations

    DEFF Research Database (Denmark)

    Wulff, Claudia; Schilder, Frank

    2014-01-01

    Relative equilibria (REs) and relative periodic orbits (RPOs) are ubiquitous in symmetric Hamiltonian systems and occur, for example, in celestial mechanics, molecular dynamics, and rigid body motion. REs are equilibria, and RPOs are periodic orbits of the symmetry reduced system. Relative Lyapunov...... center bifurcations are bifurcations of RPOs from REs corresponding to Lyapunov center bifurcations of the symmetry reduced dynamics. In this paper we first prove a relative Lyapunov center theorem by combining recent results on the persistence of RPOs in Hamiltonian systems with a symmetric Lyapunov...... center theorem of Montaldi, Roberts, and Stewart. We then develop numerical methods for the detection of relative Lyapunov center bifurcations along branches of RPOs and for their computation. We apply our methods to Lagrangian REs of the N-body problem....

  10. PARTICULARITIES REGARDING THE ESTABLISHMENT OF

    Directory of Open Access Journals (Sweden)

    NAGY CRISTINA MIHAELA

    2013-05-01

    Full Text Available Commercial companies from the insurance field have, under the law, features that distinguish them from other commercial companies in respect of the establishment and the company's operation and control. For insurance companies there is a unique authorization system, by the member state in which their head office is located (home member state, and based on this authorization they can carry out insurance activities in any member states by opening agencies or subsidiaries, with prior notification to the ISC by the authorities of those States. Apparently the number of documents required to establish a company in the insurance sector is large and the stages are laborious but necessary because the State has to act prudentially as insurance services are addressed to natural or legal persons potentially vulnerable.

  11. Move two: establishing a niche

    Directory of Open Access Journals (Sweden)

    Wasima Shehzad

    2008-04-01

    Full Text Available The significant purpose of the author in the Introduction of a research article is to convince the reader about the importance of the work to be presented. To achieve this end, a convincing “niche” needs to be built by evaluating, rejecting or indicating gaps in previous related work. The purpose of “establishing a niche” is to emphasize the current research project presented by the author. The present paper investigates how Computer scientists use this obligatory step of “Create a Research Space” (CARS model (Swales & Feak, 1994 & 2004 to highlight their own research work. This paper not only compares the results with other similar studies but also presents an in-depth analysis of various types of gap statements used in Computer Science research article Introductions. The issue of cyclicity of this step and the linguistic indicators used for the establishment of “niche” (the gap statements are both discussed.

  12. Factors affecting forage stand establishment

    Directory of Open Access Journals (Sweden)

    Sulc R.M.

    1998-01-01

    Full Text Available Significant advances have been made in our knowledge of forage seed physiology, technology, and stand establishment practices; however, stand establishment continues to be one of the most common production problems affecting forage crops in the USA. There is a need for research on stand establishment of forage crops under abiotic and biotic stress. Although the forage seed industry produces and markets seed of high quality, new methods of assessing seed vigor are needed and their use should be expanded in the industry to enable matching seed lot performance to specific environmental conditions where performance can be maximized. Seed treatment and seed coating are used in the forage seed industry, and studies have shown they are of benefit in some environments. There is an increase in no-tillage seeding of forage crops, but improvements in the no-tillage planting equipment are needed to make them better suited to small seeds. Other recent developments in seeding techniques include broadcasting seed with dry granular and fluid fertilizers, which improves the efficiency of the seeding operation.

  13. Treatment of Established Status Epilepticus

    Science.gov (United States)

    Falco-Walter, Jessica J.; Bleck, Thomas

    2016-01-01

    Status epilepticus is the most severe form of epilepsy, with a high mortality rate and high health care costs. Status epilepticus is divided into four stages: early, established, refractory, and super-refractory. While initial treatment with benzodiazepines has become standard of care for early status epilepticus, treatment after benzodiazepine failure (established status epilepticus (ESE)) is incompletely studied. Effective treatment of ESE is critical as morbidity and mortality increases dramatically the longer convulsive status epilepticus persists. Phenytoin/fosphenytoin, valproic acid, levetiracetam, phenobarbital, and lacosamide are the most frequently prescribed antiseizure medications for treatment of ESE. To date there are no class 1 data to support pharmacologic recommendations of one agent over another. We review each of these medications, their pharmacology, the scientific evidence in support and against each in the available literature, adverse effects and safety profiles, dosing recommendations, and limitations of the available evidence. We also discuss future directions including the established status epilepticus treatment trial (ESETT). Substantial further research is urgently needed to identify these patients (particularly those with non-convulsive status epilepticus), elucidate the most efficacious antiseizure treatment with head-to-head randomized prospective trials, and determine whether this differs for convulsive vs. non-convulsive ESE. PMID:27120626

  14. Treatment of Established Status Epilepticus

    Directory of Open Access Journals (Sweden)

    Jessica J. Falco-Walter

    2016-04-01

    Full Text Available Status epilepticus is the most severe form of epilepsy, with a high mortality rate and high health care costs. Status epilepticus is divided into four stages: early, established, refractory, and super-refractory. While initial treatment with benzodiazepines has become standard of care for early status epilepticus, treatment after benzodiazepine failure (established status epilepticus (ESE is incompletely studied. Effective treatment of ESE is critical as morbidity and mortality increases dramatically the longer convulsive status epilepticus persists. Phenytoin/fosphenytoin, valproic acid, levetiracetam, phenobarbital, and lacosamide are the most frequently prescribed antiseizure medications for treatment of ESE. To date there are no class 1 data to support pharmacologic recommendations of one agent over another. We review each of these medications, their pharmacology, the scientific evidence in support and against each in the available literature, adverse effects and safety profiles, dosing recommendations, and limitations of the available evidence. We also discuss future directions including the established status epilepticus treatment trial (ESETT. Substantial further research is urgently needed to identify these patients (particularly those with non-convulsive status epilepticus, elucidate the most efficacious antiseizure treatment with head-to-head randomized prospective trials, and determine whether this differs for convulsive vs. non-convulsive ESE.

  15. Encapsulating peritoneal sclerosis: experience of a tertiary referral center.

    LENUS (Irish Health Repository)

    Phelan, P J

    2010-05-01

    Encapsulating peritoneal sclerosis (EPS) is arguably the most serious complication of chronic peritoneal dialysis (PD) therapy with extremely high mortality rates. We aimed to establish the rates of EPS and factors associated with its development in a single center.

  16. INVISTA to Build a New China Research Center

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    World’s largest nylon and spandex producer establishes the state of art commercial textileresearch center in ChinaINVISTA announced building a new research facility inMainland China in September 23 to further strengthen

  17. USGS Core Research Center (CRC) Collection of Core

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The Core Research Center (CRC) was established in 1974 by the U.S. Geological Survey (USGS) to preserve valuable rock cores for use by scientists and educators from...

  18. Air Force Cyberspace Technical Center of Excellence (CyTCECR)

    Data.gov (United States)

    Federal Laboratory Consortium — The Center for Cyberspace Research (CCR), established in March 2002, conducts defense-focused research at the Master's and PhD levels. The CCR is forward-looking and...

  19. USGS Core Research Center (CRC) Collection of Cuttings

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The Core Research Center (CRC) was established in 1974 by the U.S. Geological Survey (USGS) to preserve valuable rock cores for use by scientists and educators from...

  20. Motivating Factors and Potential Deterrents to Blood Donation in High School Aged Blood Donors

    Directory of Open Access Journals (Sweden)

    Rachel Finck

    2016-01-01

    Full Text Available Background. To ensure an adequate supply of blood, collection centers must design campaigns that successfully recruit and maintain an active donor pool. Understanding factors that motivate and deter individuals from donating may help centers develop targeted recruitment campaigns. These factors among high school aged blood donors have not yet been fully investigated. Study Design and Methods. A voluntary, anonymous survey was administered to student donors at high school mobile blood drives. The survey instrument asked the students to rate several potential motivating factors in their importance in the decision to donate blood and several potential deterring factors in their future decision whether or not to donate blood again. The survey also asked the students to rate the desirability of several potential incentives. Results. Motivating factors that reflected prosocial, empathetic, and altruistic thoughts and beliefs were rated highly by students. Pain from phlebotomy was most commonly chosen as potential deterrent. Movie tickets and cookies/snacks at the drive were rated as the most attractive incentives. Conclusion. High school aged blood donors are similar to other donor groups in their expressed motives for donating blood. This group may be unique in the factors that deter them from donating and in their preferences for different incentives.

  1. ANALYSIS THE EFFECTS OF SMOKING CONTROL AFTER ESTABLISHING NO-SMOKING HEALTH AGENCIES IN SHIJIAZHUANG CENTER FOR DISEASE CONTROL AND PREVENTION%石家庄市疾病预防控制中心创建无烟卫生机构后控烟效果分析

    Institute of Scientific and Technical Information of China (English)

    董会敏; 李正光; 信云; 段巧红; 姜彩肖; 闫玉英; 马新颜

    2011-01-01

    [目的]探索无烟机构创建方法,评价创建无烟机构后控烟效果. [方法]按照国家2008年3月印发的《无烟医疗卫生机构标准(试行)》在本单位开展无烟机构创建活动,创建前后分别随机抽取100人左右进行问卷调查.[结果]对烟草危害认知情况,干预后总知晓率89.4%显著高于干预前的61.0%(X2=137.481,P=0.000).对吸烟与疾病的关系认知情况,干预后总知晓率84.7%,显著高于干预前69.6%(X2=47.542,P==0.000).对被动吸烟与疾病关系知晓情况,干预后总知晓率为86.1%显著高于干预前的73.0%(X2=33.725,P=0.000).创建前、后吸烟率分别为16.5%和12.0%,差异无统计学意义(X2=0.863,P=0.353).干预前后没有被动吸烟的人数分别占53.5%和6%,差异有统计学意义(X2=10.931,P=0.001).[结论]石家庄市疾病中心创建无烟机构取得了较好效果.%[Objective] To explore the establishing methods of no-smoking health agencies and analyze the effects of smoking control. [Methods] Through random sampling, about 100 persons were interviewed before and after establishing no-smoking health agencies. [ Results] After the intervention, the awareness rales of tobacco dangers, relationship between smoking and disease and relationship between passive smoking and disease were 89.4% , 84.7% and 86.1% , the awareness rates were higher than that before intervention. The smoking rate was 16.5% before the intervention and 12.0% after the intervention. Before and after the intervention, the ratios of no-passive smoking were 53.5% and 6%. [Conclusion] The intervention indicates the remarkable results.

  2. Energy efficient data centers

    Energy Technology Data Exchange (ETDEWEB)

    Tschudi, William; Xu, Tengfang; Sartor, Dale; Koomey, Jon; Nordman, Bruce; Sezgen, Osman

    2004-03-30

    Data Center facilities, prevalent in many industries and institutions are essential to California's economy. Energy intensive data centers are crucial to California's industries, and many other institutions (such as universities) in the state, and they play an important role in the constantly evolving communications industry. To better understand the impact of the energy requirements and energy efficiency improvement potential in these facilities, the California Energy Commission's PIER Industrial Program initiated this project with two primary focus areas: First, to characterize current data center electricity use; and secondly, to develop a research ''roadmap'' defining and prioritizing possible future public interest research and deployment efforts that would improve energy efficiency. Although there are many opinions concerning the energy intensity of data centers and the aggregate effect on California's electrical power systems, there is very little publicly available information. Through this project, actual energy consumption at its end use was measured in a number of data centers. This benchmark data was documented in case study reports, along with site-specific energy efficiency recommendations. Additionally, other data center energy benchmarks were obtained through synergistic projects, prior PG&E studies, and industry contacts. In total, energy benchmarks for sixteen data centers were obtained. For this project, a broad definition of ''data center'' was adopted which included internet hosting, corporate, institutional, governmental, educational and other miscellaneous data centers. Typically these facilities require specialized infrastructure to provide high quality power and cooling for IT equipment. All of these data center types were considered in the development of an estimate of the total power consumption in California. Finally, a research ''roadmap'' was developed

  3. 75 FR 26780 - Request for Comment: National Center for Complementary and Alternative Medicine Announcement of...

    Science.gov (United States)

    2010-05-12

    ... Comment: National Center for Complementary and Alternative Medicine Announcement of Strategic Planning White Papers ACTION: Notice. SUMMARY: The National Center for Complementary and Alternative Medicine... for Complementary and Alternative Medicine (NCCAM) was established in 1998 with the mission...

  4. Genetics Blood Card Use

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — SOP guiding collection of blood for genetics analysis. Provides stepwise instructions and guidance on how to collect DNA sample using a whole blood blot card

  5. Blood Clotting and Pregnancy

    Medline Plus

    Full Text Available ... known as venous thromboembolism, are highly preventable (see prevention tips below). The U.S. Surgeon General has issued ... blood conditions and increase research on the causes, prevention, and treatment. Blood clots are also potentially dangerous ...

  6. Blood Clotting and Pregnancy

    Medline Plus

    Full Text Available ... pregnancy: Be aware of risk factors. Know your family history. Make sure your doctor knows about any ... blood clots or blood clotting disorders in your family. Remain active, with your doctor's approval. Be aware ...

  7. Chloride test - blood

    Science.gov (United States)

    ... disease Antidiuretic hormone blood test Gastric suction Heart failure - overview Hyperventilation Ions Metabolic acidosis Multiple endocrine neoplasia (MEN) II Proximal renal tubular acidosis Respiratory acidosis Sodium blood test Review Date 5/3/2015 Updated by: Laura J. ...

  8. High blood pressure medications

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/007484.htm High blood pressure medicines To use the sharing features on this page, please enable JavaScript. Treating high blood pressure will help prevent problems such as heart disease, ...

  9. Blood Pressure Medicines

    Science.gov (United States)

    High blood pressure, also called hypertension, usually has no symptoms. But it can cause serious problems such as stroke, ... kidney failure. If you cannot control your high blood pressure through lifestyle changes such as losing weight ...

  10. White Blood Cell Disorders

    Science.gov (United States)

    ... Fundamentals Heart and Blood Vessel Disorders Hormonal and Metabolic Disorders Immune Disorders Infections Injuries and Poisoning Kidney and ... Fundamentals Heart and Blood Vessel Disorders Hormonal and Metabolic Disorders Immune Disorders Infections Injuries and Poisoning Kidney and ...

  11. Low blood sugar - newborns

    Science.gov (United States)

    ... medlineplus.gov/ency/article/007306.htm Low blood sugar - newborns To use the sharing features on this page, please enable JavaScript. A low blood sugar level in newborn babies is also called neonatal ...

  12. Blood Transfusions (For Teens)

    Science.gov (United States)

    ... many precautions to confirm a patient's and donor's blood are compatible before giving a transfusion. In almost every situation, the benefits of having a blood transfusion far outweigh the risks. The Red Cross ...

  13. High blood cholesterol levels

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/000403.htm High blood cholesterol levels To use the sharing features ... stroke, and other problems. The medical term for high blood cholesterol is lipid disorder, hyperlipidemia, or hypercholesterolemia. ...

  14. Pros and cons of the ambulatory surgery center joint venture.

    Science.gov (United States)

    Giannini, Deborah

    2008-01-01

    If a physician group has determined that it has a realistic patient base to establish an ambulatory surgery center, it may be beneficial to consider a partner to share the costs and risks of this new joint venture. Joint ventures can be a benefit or liability in the establishment of an ambulatory surgery center. This article discusses the advantages and disadvantages of a hospital physician-group joint venture.

  15. Costing blood products and services.

    Science.gov (United States)

    Wallace, E L

    1991-05-01

    At present, blood centers and transfusion services have limited alternatives for offsetting the ever-rising costs of health care inputs. In the face of current revenue constraints, cost reduction or cost containment through efficiency improvements or service reduction is the principal available means. Such methods ought to be pursued vigorously by blood bankers with the aid of well-designed costing and other physical measurements systems. Experience indicates, however, that blood bankers, in their attempts to reduce or contain costs, are likely to place undue reliance on cost accounting systems as the means of capturing sought-for benefits. Management must learn enough about methods of costing to judge directly the uses and limitations of the information produced. Such understanding begins with recognition that all costs and cost comparisons should be specific to the purpose for which they are developed. No costing procedure is capable of producing measures generally applicable to all management decisions. A measure relevant to a planning decision is unlikely to be appropriate for performance evaluation. Useful comparisons among sets of organizations of costs, or of measures of physical inputs and outputs, require assurance that the methods of measurement employed are the same and that the sets of organizations from which the measures are drawn are reasonably comparable.

  16. 78 FR 6762 - Food and Drug Administration Food Safety Modernization Act: Proposed Rules To Establish Standards...

    Science.gov (United States)

    2013-01-31

    ..., Center for Food Safety and Applied Nutrition (HFS-009), Food and Drug Administration, 5100 Paint Branch... amends the Federal Food, Drug, and Cosmetic Act (the FD&C Act) to establish the foundation of...

  17. Comparative Study of Protocols Used for Establishing VPN

    CERN Document Server

    Venkateswari, P

    2010-01-01

    This is an Internet era. Most of the organizations try to establish their development centers and branch offices across the World. Employees working from their homes are also becoming very popular and organizations benefit financially by utilizing less office space, and reducing total expenses incurred by having office workers on site. To meet such requirements organizations develop a need to communicate with these offices over highly secure, confidential and reliable connections regardless of the location of the office. Here the VPN plays a vital role in establishing a distributed business model.

  18. Comparative Study of Protocols Used for Establishing VPN

    Directory of Open Access Journals (Sweden)

    P. Venkateswari

    2009-12-01

    Full Text Available This is an Internet era. Most of the organizations try to establish their development centers and branch offices across the World. Employees working from their homes are also becoming very popular and organizations benefit financially by utilizing less office space, and reducing total expenses incurred by having office workers on site. To meet such requirements organizations develop a need to communicate with these offices over highly secure, confidential and reliable connections regardless of the location of the office. Here the VPN plays a vital role in establishing a distributed business model.

  19. The establishment and characteristics of China's extradition system

    Institute of Scientific and Technical Information of China (English)

    HUANG Feng

    2006-01-01

    Through analyzing the 25 bilateral extradition treaties that China concluded with other countries and the background of relevant legislation and treaty conclusion,the author delineates and discusses the establishment and basic characteristics of China's extradition system.These characteristics are mainly as follows:(a) introduction of basic rules through bilateral treaties;(b) establishment of a scientific double examination to standardize and formalize extradition cooperation;(c) principle-centered,flexible and open towards extradition cooperation,and take the extradited person as a party to the extradition proceedings and give attention to the protection of his human fights.

  20. Rh Factor Blood Test

    Science.gov (United States)

    Tests and Procedures Rh factor blood test By Mayo Clinic Staff Rhesus (Rh) factor is an inherited protein found on the surface of ... If your blood has the protein, you're Rh positive. If your blood lacks the protein, you' ...

  1. High Blood Pressure Facts

    Science.gov (United States)

    ... More black women than men have high blood pressure. 2 Race of Ethnic Group Men (%) Women (%) African Americans 43.0 45.7 Mexican Americans 27.8 28.9 Whites 33.9 31.3 All 34.1 32.7 Top of Page Why Blood Pressure Matters View this graphic snapshot of blood pressure ...

  2. The Rockefeller Archive Center: A Reservoir of Information.

    Science.gov (United States)

    Ernst, Joseph W.

    1982-01-01

    The Rockefeller Archive Center was established in 1974 to bring together the records of The Rockefeller University, the Rockefeller Brothers Fund, Inc., the Rockefeller family, and others. This history of the Archive Center and description of its holdings focuses on those areas of special interest to educational researchers. (Author/BW)

  3. Current Practice and Infrastructures for Campus Centers of Community Engagement

    Science.gov (United States)

    Welch, Marshall; Saltmarsh, John

    2013-01-01

    This article provides an overview of current practice and essential infrastructure of campus community engagement centers in their efforts to establish and advance community engagement as part of the college experience. The authors identified key characteristics and the prevalence of activities of community engagement centers at engaged campuses…

  4. The Administrative Assessment Center: An Opportunity for Service.

    Science.gov (United States)

    Richardson, M. D.

    In 1988, the Department of Educational Leadership at Western Kentucky University (WKU) established the Western Kentucky Assessment Center, sponsored by the National Association of Secondary School Principals (NASSP). This document provides an overview of the history and methods of NASSP assessment centers, followed by a discussion of costs to…

  5. Cord blood transplantation: can we make it better?

    Directory of Open Access Journals (Sweden)

    Leland eMetheny

    2013-09-01

    Full Text Available Umbilical cord blood is an established source of hematopoietic stem cells for transplantation. It enjoys several advantages over bone marrow or peripheral blood, including increased tolerance for Human Leukocyte Antigen mismatches, decreased incidence of graft-versus-host disease, and easy availability. Unrelated cord blood does have limitations, however, especially in the treatment of adults. In the 24 years since the first umbilical cord blood transplant was performed, significant progress has been made, but delayed hematopoietic engraftment and increased treatment related mortality remain obstacles to widespread use. Here we summarize the latest results of unrelated cord blood transplants, and review strategies under investigation to improve clinical outcomes.

  6. A well-established profession

    DEFF Research Database (Denmark)

    Braae, Ellen Marie; Hare, Richard Andrew

    2011-01-01

    It was during the economic boom of the 1960s that the demand for landscape architects began to explode in Denmark as the expanding welfare state brought about rapid physical changes. At this time the country’s first specific education for landscape architects was established and 2010 marked the 5......th anniversary of landscape architecture teaching, at the Faculty of Life Science – the University of Copenhagen(KU-Life). It’s origins can be traced further back but, then as now, the essence of the education is that of creating a dynamic synergy of the sciences and the arts....

  7. Virginia Tech creates Caribbean center for education and research

    OpenAIRE

    Felker, Susan B.

    2006-01-01

    Virginia Tech has established a research, education, and outreach center in the Caribbean that will serve as part of a broad strategy to create international centers of scholarship around the world. The Caribbean Center for Education and Research (CCER) in Punta Cana, on the eastern tip of the Dominican Republic, will allow Virginia Tech faculty to conduct research as well as instruct students on biodiversity, environmental and social sustainability, global issues in natural resources, and ho...

  8. Establishing nuclear facility drill programs

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    The purpose of DOE Handbook, Establishing Nuclear Facility Drill Programs, is to provide DOE contractor organizations with guidance for development or modification of drill programs that both train on and evaluate facility training and procedures dealing with a variety of abnormal and emergency operating situations likely to occur at a facility. The handbook focuses on conducting drills as part of a training and qualification program (typically within a single facility), and is not intended to included responses of personnel beyond the site boundary, e.g. Local or State Emergency Management, Law Enforcement, etc. Each facility is expected to develop its own facility specific scenarios, and should not limit them to equipment failures but should include personnel injuries and other likely events. A well-developed and consistently administered drill program can effectively provide training and evaluation of facility operating personnel in controlling abnormal and emergency operating situations. To ensure the drills are meeting their intended purpose they should have evaluation criteria for evaluating the knowledge and skills of the facility operating personnel. Training and evaluation of staff skills and knowledge such as component and system interrelationship, reasoning and judgment, team interactions, and communications can be accomplished with drills. The appendices to this Handbook contain both models and additional guidance for establishing drill programs at the Department`s nuclear facilities.

  9. National Automotive Center - NAC

    Data.gov (United States)

    Federal Laboratory Consortium — Encouraged by the advantages of collaboration, the U.S. Army Tank Automotive Research, Development and Engineering Center (TARDEC) worked with the Secretary of the...

  10. Test Control Center

    Science.gov (United States)

    2000-01-01

    At the test observation periscope in the Test Control Center exhibit in StenniSphere at the John C. Stennis Space Center in Hancock County, Miss., visitors can observe a test of a Space Shuttle Main Engine exactly as test engineers might see it during a real engine test. The Test Control Center exhibit exactly simulates not only the test control environment, but also the procedure of testing a rocket engine. Designed to entertain while educating, StenniSphere includes informative dispays and exhibits from NASA's lead center for rocket propulsion and remote sensing applications. StenniSphere is open free of charge from 9 a.m. to 5 p.m. daily.

  11. Cooperative Tagging Center (CTC)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Cooperative Tagging Center (CTC) began as the Cooperative Game Fish Tagging Program (GTP) at Woods Hole Oceanographic Institute (WHOI) in 1954. The GTP was...

  12. Center for Contaminated Sediments

    Data.gov (United States)

    Federal Laboratory Consortium — The U.S. Army Corps of Engineers Center for Contaminated Sediments serves as a clearinghouse for technology and expertise concerned with contaminated sediments. The...

  13. Reliability Centered Maintenance - Methodologies

    Science.gov (United States)

    Kammerer, Catherine C.

    2009-01-01

    Journal article about Reliability Centered Maintenance (RCM) methodologies used by United Space Alliance, LLC (USA) in support of the Space Shuttle Program at Kennedy Space Center. The USA Reliability Centered Maintenance program differs from traditional RCM programs because various methodologies are utilized to take advantage of their respective strengths for each application. Based on operational experience, USA has customized the traditional RCM methodology into a streamlined lean logic path and has implemented the use of statistical tools to drive the process. USA RCM has integrated many of the L6S tools into both RCM methodologies. The tools utilized in the Measure, Analyze, and Improve phases of a Lean Six Sigma project lend themselves to application in the RCM process. All USA RCM methodologies meet the requirements defined in SAE JA 1011, Evaluation Criteria for Reliability-Centered Maintenance (RCM) Processes. The proposed article explores these methodologies.

  14. The ORFEUS Data Center

    Directory of Open Access Journals (Sweden)

    B. Dost

    1994-06-01

    Full Text Available 1993 the ORFEUS Data Center (ODC; Dost, 1991 changed hosting organisation. It moved within the Netherlands from the University of Utrecht to the Royal Netherlands Meteorological Institute (KNM1 in de Bilt. This change in hosting organisation was necessary to ensure a longer term stability in the operation of the ODC. Key issues for the ODC are the rapid on-line data access and quality controlled, complete and efficient off-line data access. During 1992 the ODC became the European node in the international SPYDER system which provides near real-time access to digital broadband data from selected high quality stations. Electronic messages trigger soveral centers well distributed over the globe. These centers then collect the data by modem from selected stations in their region. Finally, data are distributed between data centers over internet.

  15. Advanced data center economy

    OpenAIRE

    Sukhov, R.; Amzarakov, M.; E. Isaev

    2013-01-01

    The article addresses basic Data Centers (DC) drivers of price and engineering, which specify rules and price evaluation for creation and further operation. DC energy efficiency concept, its influence on DC initial price, operation costs and Total Cost of Ownership.

  16. Center Innovation Fund Program

    Data.gov (United States)

    National Aeronautics and Space Administration — To stimulate and encourage creativity and innovation within the NASA Centers. The activities are envisioned to fall within the scope of NASA Space Technology or...

  17. Global Hydrology Research Center

    Data.gov (United States)

    National Aeronautics and Space Administration — The GHRC is the data management and user services arm of the Global Hydrology and Climate Center. It encompasses the data and information management, supporting...

  18. National Farm Medicine Center

    Science.gov (United States)

    Research Areas Applied Sciences Biomedical Informatics Clinical Research Epidemiology Farm Medicine Human Genetics Oral-Systemic Health Clinical ... Consulting Agritourism Farm MAPPER Lyme Disease ROPS Rebate Zika Virus National Farm Medicine Center The National Farm ...

  19. Hazardous Waste Research Center

    Data.gov (United States)

    Federal Laboratory Consortium — A full-service research and evaluation center equipped with safety equipment, a high-bay pilot studies area, and a large-scale pilot studies facility The U.S. Army...

  20. Carbon Monoxide Information Center

    Medline Plus

    Full Text Available ... Community Outreach Resource Center Toy Recall Statistics CO Poster Contest Pool Safely Business & Manufacturing Business & Manufacturing Business ... Featured Resources CPSC announces winners of carbon monoxide poster contest Video View the blog Clues You Can ...

  1. World Trade Center

    Index Scriptorium Estoniae

    2006-01-01

    Esilinastus katastroofifilm "World Trade Center" : stsenarist Andrea Berloff : režissöör Oliver Stone : kunstnik Jan Roelfs : osades Nicholas Cage, Michael Pena, Stephen Dorff jpt : Ameerika Ühendriigid 2006. Ka filmi prototüüpidest

  2. Health Center Controlled Network

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Health Center Controlled Network (HCCN) tool is a locator tool designed to make data and information concerning HCCN resources more easily available to our...

  3. USU Patient Simulation Center

    Data.gov (United States)

    Federal Laboratory Consortium — he National Capital Area (NCA) Medical Simulation Center is a state-of-the-art training facility located near the main USU campus. It uses simulated patients (i.e.,...

  4. HUD Homeownership Centers

    Data.gov (United States)

    Department of Housing and Urban Development — HUD Homeownership Centers (HOCs) insure single family Federal Housing Administration (FHA) mortgages and oversee the selling of HUD homes. FHA has four Homeownership...

  5. Mental Health Screening Center

    Science.gov (United States)

    ... Releases & Announcements Public Service Announcements Partnering with DBSA Mental Health Screening Center These online screening tools are not ... you have any concerns, see your doctor or mental health professional. Depression This screening form was developed from ...

  6. FEMA Disaster Recovery Centers

    Data.gov (United States)

    Department of Homeland Security — This is a search site for FEMA's Disaster Recovery Centers (DRC). A DRC is a readily accessible facility or mobile office set up by FEMA where applicants may go for...

  7. Centering in Japanese Discourse

    CERN Document Server

    Walker, M; Côté, S; Walker, Marilyn; Iida, Masayo; Cote, Sharon

    1996-01-01

    In this paper we propose a computational treatment of the resolution of zero pronouns in Japanese discourse, using an adaptation of the centering algorithm. We are able to factor language-specific dependencies into one parameter of the centering algorithm. Previous analyses have stipulated that a zero pronoun and its cospecifier must share a grammatical function property such as {\\sc Subject} or {\\sc NonSubject}. We show that this property-sharing stipulation is unneeded. In addition we propose the notion of {\\sc topic ambiguity} within the centering framework, which predicts some ambiguities that occur in Japanese discourse. This analysis has implications for the design of language-independent discourse modules for Natural Language systems. The centering algorithm has been implemented in an HPSG Natural Language system with both English and Japanese grammars.

  8. Accredited Birth Centers

    Science.gov (United States)

    ... 9743 Accredited since January 2016 98 Bright Eyes Midwifery and Wild Rivers Women's Health Accredited 29135 Ellensburg ... Accredited since November 2015 96 Footprints in Time Midwifery Services and Birth Center Accredited 351 N. Water ...

  9. Advanced Missile Signature Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Missile Signature Center (AMSC) is a national facility supporting the Missile Defense Agency (MDA) and other DoD programs and customers with analysis,...

  10. Collection and establishment of annonaceae in El Salvador.

    OpenAIRE

    Cruz, Eduardo; Deras, Héctor

    2006-01-01

    The national center of agricultural and forest technology (CENTA), through its unit of phytogenetic resources, under took a collecting survey of annonacea species in 1998, with the objective of exploring, collect, characterize and establish collections in the experimental stations. This survey was carried out at a national level visiting properties and markets. Evaluated traits for fruits were: weight , lenght and diameter, number of seeds, texture of shell and pulp, form of fruit and carpels...

  11. Data center cooling system

    Energy Technology Data Exchange (ETDEWEB)

    Chainer, Timothy J; Dang, Hien P; Parida, Pritish R; Schultz, Mark D; Sharma, Arun

    2015-03-17

    A data center cooling system may include heat transfer equipment to cool a liquid coolant without vapor compression refrigeration, and the liquid coolant is used on a liquid cooled information technology equipment rack housed in the data center. The system may also include a controller-apparatus to regulate the liquid coolant flow to the liquid cooled information technology equipment rack through a range of liquid coolant flow values based upon information technology equipment temperature thresholds.

  12. National Biocontainment Training Center

    Science.gov (United States)

    2015-08-01

    than ever before as scientists push to understand the pathology and develop diagnostics, vaccines and therapeutics for deadly diseases like Ebola...Hardcastle, Vickie Jones, Sheri Leavitt, and Belinda Rivera. Gulf Coast Consortium Postdoctoral Veterinary Training Program - A clinical veterinarian from...the Center for Comparative Medicine at Baylor College of Medicine in Houston and a veterinarian from the University of Texas Health Science Center

  13. Cancer and blood coagulation.

    Science.gov (United States)

    Boccaccio, C; Medico, E

    2006-05-01

    In human patients, blood coagulation disorders often associate with cancer, even in its early stages. Recently, in vitro and in vivo experimental models have shown that oncogene expression, or inactivation of tumour suppressor genes, upregulate genes that control blood coagulation. These studies suggest that activation of blood clotting, leading to peritumoral fibrin deposition, is instrumental in cancer development. Fibrin can indeed build up a provisional matrix, supporting the invasive growth of neoplastic tissues and blood vessels. Interference with blood coagulation can thus be considered as part of a multifaceted therapeutic approach to cancer.

  14. University of Illinois FRIENDS Children’s Environmental Health Center

    Data.gov (United States)

    Federal Laboratory Consortium — The FRIENDS Children's Environmental Health Center at the University of Illinois, Urbana-Champaign, was established in 2001 to investigate the interactive effects of...

  15. Spontaneous germinal centers and autoimmunity.

    Science.gov (United States)

    Domeier, Phillip P; Schell, Stephanie L; Rahman, Ziaur S M

    2017-02-01

    Germinal centers (GCs) are dynamic microenvironments that form in the secondary lymphoid organs and generate somatically mutated high-affinity antibodies necessary to establish an effective humoral immune response. Tight regulation of GC responses is critical for maintaining self-tolerance. GCs can arise in the absence of purposeful immunization or overt infection (called spontaneous GCs, Spt-GCs). In autoimmune-prone mice and patients with autoimmune disease, aberrant regulation of Spt-GCs is thought to promote the development of somatically mutated pathogenic autoantibodies and the subsequent development of autoimmunity. The mechanisms that control the formation of Spt-GCs and promote systemic autoimmune diseases remain an open question and the focus of ongoing studies. Here, we discuss the most current studies on the role of Spt-GCs in autoimmunity.

  16. Southern Energy Efficiency Center (SEEC)

    Energy Technology Data Exchange (ETDEWEB)

    Vieira, Robin; Sonne, Jeffrey; Withers, Charles; Cummings, James; Verdict, Malcolm; Roberts, Sydney

    2009-09-30

    The Southern Energy Efficiency Center (SEEC) builds collaborative partnerships with: state and local governments and their program support offices, the building delivery industry (designers, contractors, realtors and commissioning agents), product manufacturers and their supply chains, utilities and their program implementers, consumers and other stakeholders in order to forge a strong regional network of building energy efficiency allies. Through a project Steering Committee composed of the state energy offices and building industry stakeholders, the SEEC works to establish consensus-based goals, priorities and strategies at the regional, state and local levels that will materially advance the deployment of high-performance “beyond code” buildings. In its first Phase, SEEC will provide limited technical and policy support assistance, training, certification and education to a wide spectrum of the building construction, codes and standards, and the consumer marketplace.

  17. Annual report of Kansai Research Establishment 2000. April 1, 2000 - March 31, 2001

    Energy Technology Data Exchange (ETDEWEB)

    Harami, Taikan; Hamaya, Nozomu; Mizuki, Jun-ichiro (eds.) [Japan Atomic Energy Research Inst., Kizu, Kyoto (Japan). Kansai Research Establishment] [and others

    2002-02-01

    This report is the second issue of the annual report of Kansai Research Establishment, Japan Atomic Energy Research Institute. It covers status reports of R and D and results of experiments conducted at the Advanced Photon Research Center and the Synchrotron Radiation Research Center during the period from April 1, 2000 to March 31, 2001. (author)

  18. Annual report of Kansai Research Establishment 1999. October 1, 1995 - March 31, 2000

    Energy Technology Data Exchange (ETDEWEB)

    Arisawa, Takashi; Shimomura, Osamu; Nagashima, Akira [eds.] [Japan Atomic Energy Research Inst., Kansai Research Establishment, Kizu, Kyoto (JP)] [and others

    2001-03-01

    This report is the first issue of the annual report of Kansai Research Establishment, Japan Atomic Energy Research Institute. It covers status reports of R and D and results of experiments conducted at the Advanced Photon Research Center and the Synchrotron Radiation Research Center during the period from October 1, 1995 to March 31, 2000. (author)

  19. Annual report of Kansai Research Establishment 2001. April 1, 2001 - March 31, 2002

    Energy Technology Data Exchange (ETDEWEB)

    Tajima, Toshiki; Harami, Taikan; Kawanishi, Shun-ichi (eds.) [Japan Atomic Energy Research Inst., Kansai Research Establishment, Kizu, Kyoto (JP)] [and others

    2003-02-01

    This report is the third issue of the annual report of Kansai Research Establishment, Japan Atomic Energy Research Institute. It covers status reports of R and D and results of experiments conducted at the Advanced Photon Research Center and the Synchrotron Radiation Research Center during the period from April 1, 2001 to March 31, 2002. (author)

  20. Blood groups systems

    Directory of Open Access Journals (Sweden)

    Ranadhir Mitra

    2014-01-01

    Full Text Available International Society of Blood Transfusion has recently recognized 33 blood group systems. Apart from ABO and Rhesus system, many other types of antigens have been noticed on the red cell membranes. Blood grouping and cross-matching is one of the few important tests that the anaesthesiologist orders during perioperative period. Hence, a proper understanding of the blood group system, their clinical significance, typing and cross-matching tests, and current perspective are of paramount importance to prevent transfusion-related complications. Nonetheless, the knowledge on blood group system is necessary to approach blood group-linked diseases which are still at the stage of research. This review addresses all these aspects of the blood groups system.

  1. Blood pressure circadian rhythm and obesity: Blood pressure variations and obesity

    Directory of Open Access Journals (Sweden)

    Despotović Nebojša

    2002-01-01

    Full Text Available Introduction The association between obesity and arterial hypertension has been established in a great number of studies. Our objective was to investigate whether circadian rhythm of blood pressure is disturbed among obese people. Material and methods In this cross-sectional, randomized study, Schiller BR-102 device was used for ambulatory blood pressure monitoring. One hundred and twenty outpatients were divided into three randomized groups: obese body mass index 30 kg/m2 (52 patients, overweight (28 patients, with body mass index 25,0-29,9 kg/m2 and normal weight (control group (48 patients, with body mass index 18,5-24,9 kg/m2. In all patients we investigated the following blood pressure parameters: average blood pressure (total, day-time and night-time, maximal blood pressure and dipping or non-dipping blood pressure pattern during night (for systolic and diastolic blood pressure, respectively. Results In body mass index beyond 30 kg/m2 only systolic blood pressure parameters were significantly higher - average blood pressure - during daytime (P=0.034 and during night (P=0.014; maximal blood pressure (P=0.001. In body mass index beyond 30 kg/m2, absence of normal blood pressure during night was significantly more often registered (P=0.007. Discussion and Conclusion The non-dipping blood pressure pattern and increase of systolic blood pressure only reveal hyper activation of sympathetic nervous system as a leading pathophysiological mechanism causing arterial hypertension in obese patients.

  2. Monitoring Blood Sugar: The Importance of Checking Blood Sugar Levels

    Science.gov (United States)

    ... Your 1- to 2-Year-Old Monitoring Blood Sugar KidsHealth > For Parents > Monitoring Blood Sugar Print A ... Tests Record Keeping The Importance of Checking Blood Sugar Levels Besides helping to keep blood sugar levels ( ...

  3. Monitoring Blood Sugar: The Importance of Checking Blood Sugar Levels

    Science.gov (United States)

    ... Feeding Your 1- to 2-Year-Old Monitoring Blood Sugar KidsHealth > For Parents > Monitoring Blood Sugar A ... Other Tests Record Keeping The Importance of Checking Blood Sugar Levels Besides helping to keep blood sugar ...

  4. Sociological establishment of 'normative facts'

    Directory of Open Access Journals (Sweden)

    Vukićević Slobodan

    2002-01-01

    Full Text Available Every science is searching for 'it's facts', it's concept and categorical decree, and by this defines specific subject of it's science researching. Here, the researching is steered on identification of ontological contents of 'normative fact' in the aim of comprehension of it's categorical entity and conceptual disposition.'The normative fact' refers to importance, significance and sense which norm has, in other words, which is attributed to the norm by man and society, and which in the air of importance influence on it's behavior. Exclusive term of sociological science is 'normative fact' as behavior of an individual, groups, institutions and society with regard to establishment, application and changes of social norms.

  5. The Northeast Climate Science Center

    Science.gov (United States)

    Ratnaswamy, M. J.; Palmer, R. N.; Morelli, T.; Staudinger, M.; Holland, A. R.

    2013-12-01

    The Department of Interior Northeast Climate Science Center (NE CSC) is part of a federal network of eight Climate Science Centers created to provide scientific information, tools, and techniques that managers and other parties interested in land, water, wildlife and cultural resources can use to anticipate, monitor, and adapt to climate change. Recognizing the critical threats, unique climate challenges, and expansive and diverse nature of the northeast region, the University of Massachusetts Amherst, College of Menominee Nation, Columbia University, Marine Biological Laboratory, University of Minnesota, University of Missouri Columbia, and University of Wisconsin-Madison have formed a consortium to host the NE CSC. This partnership with the U.S. Geological Survey climate science center network provides wide-reaching expertise, resources, and established professional collaborations in both climate science and natural and cultural resources management. This interdisciplinary approach is needed for successfully meeting the regional needs for climate impact assessment, adaptive management, education, and stakeholder outreach throughout the northeast region. Thus, the NE CSC conducts research, both through its general funds and its annual competitive award process, that responds to the needs of natural resource management partners that exist, in part or whole, within the NE CSC bounds. This domain includes the North Atlantic, Upper Midwest and Great Lakes, Eastern Tallgrass and Big Rivers, and Appalachian Landscape Conservation Cooperatives (LCCs), among other management stakeholders. For example, researchers are developing techniques to monitor tree range dynamics as affected by natural disturbances which can enable adaptation of projected climate impacts; conducting a Designing Sustainable Landscapes project to assess the capability of current and potential future landscapes in the Northeast to provide integral ecosystems and suitable habitat for a suite of

  6. Dietary fiber and blood pressure control.

    Science.gov (United States)

    Aleixandre, A; Miguel, M

    2016-04-01

    In the past few years, new strategies to control blood pressure levels are emerging by developing new bioactive components of foods. Fiber has been linked to the prevention of a number of cardiovascular diseases and disorders. β-Glucan, the main soluble fiber component in oat grains, was initially linked to a reduction in plasma cholesterol. Several studies have shown afterward that dietary fiber may also improve glycaemia, insulin resistance and weight loss. The effect of dietary fiber on arterial blood pressure has been the subject of far fewer studies than its effect on the above-mentioned variables, but research has already shown that fiber intake can decrease arterial blood pressure in hypertensive rats. Moreover, certain fibers can improve arterial blood pressure when administered to hypertensive and pre-hypertensive subjects. The present review summarizes all those studies which attempt to establish the antihypertensive effects of dietary fiber, as well as its effect on other cardiovascular risk factors.

  7. The effects of blood pressure reduction and of different blood pressure-lowering regimens on major cardiovascular events according to baseline blood pressure : meta-analysis of randomized trials

    NARCIS (Netherlands)

    Czernichow, Sebastien; Zanchetti, Alberto; Turnbull, Fiona; Barzi, Federica; Ninomiya, Toshiaru; Kengne, Andre-Pascal; Lambers Heerspink, Hiddo J.; Perkovic, Vlado; Huxley, Rachel; Arima, Hisatomi; Patel, Anushka; Chalmers, John; Woodward, Mark; MacMahon, Stephen; Neal, Bruce

    2011-01-01

    Background The benefits of reducing blood pressure are well established, but there remains uncertainty about whether the magnitude of the effect varies with the initial blood pressure level. The objective was to compare the risk reductions achieved by different blood pressure-lowering regimens among

  8. So You Want to Start a Peer Online Writing Center?

    Directory of Open Access Journals (Sweden)

    Christine Rosalia

    2013-03-01

    Full Text Available The purpose of this article is to share lessons learned in setting up three different peer online writing centers in three different contexts (EFL, Generation 1.5, and ESL. In each center the focus was on the language learner as a peer online writing advisor and their needs in maintaining centers “for and by” learners. Technology affordances and constraints for local contexts, which promote learner autonomy, are analyzed. The open-source platforms (Moodle, Drupal, and Google Apps are compared in terms of usability for peer writing center work, particularly centers where groups co-construct feedback for writers, asynchronously. This paper is useful for readers who would like a head start or deeper understanding of potential logistics and decision-making involved in establishing a peer online writing center within coursework and/or a self-access learning center.

  9. Blood-brain barrier dysfunction in Parkinsonian midbrain in vivo

    NARCIS (Netherlands)

    Kortekaas, R; Leenders, KL; van Oostrom, JCH; Vaalburg, W; Bart, J; Willemsen, ATM; Hendrikse, NH

    2005-01-01

    Parkinson's disease (PD) is associated with a loss of neurons from the midbrain. The cause of PD is unknown, but it is established that certain neurotoxins can cause similar syndromes. The brain is normally protected from these noxious blood-borne chemicals by the blood-brain barrier which includes

  10. Chronic blood pressure control.

    Science.gov (United States)

    Brands, Michael W

    2012-10-01

    Chronic blood pressure is maintained within very narrow limits around an average value. However, the multitude of physiologic processes that participate in blood pressure control present a bewildering array of possibilities to explain how such tight control of arterial pressure is achieved. Guyton and Coleman and colleagues addressed this challenge by creating a mathematical model that integrated the short- and long-term control systems for overall regulation of the circulation. The hub is the renal-body fluid feedback control system, which links cardiac function and vascular resistance and capacitance with fluid volume homeostasis as the foundation for chronic blood pressure control. The cornerstone of that system is renal sodium excretory capability, which is defined by the direct effect of blood pressure on urinary sodium excretion, that is, "pressure natriuresis." Steady-state blood pressure is the pressure at which pressure natriuresis balances sodium intake over time; therefore, renal sodium excretory capability is the set point for chronic blood pressure. However, this often is misinterpreted as dismissing, or minimizing, the importance of nonrenal mechanisms in chronic blood pressure control. This article explains the renal basis for the blood pressure set point by focusing on the absolute dependence of our survival on the maintenance of sodium balance. Two principal threats to sodium balance are discussed: (1) a change in sodium intake or renal excretory capability and (2) a change in blood pressure. In both instances, circulatory homeostasis is maintained because the sodium balance blood pressure set point is reached.

  11. Engineer Research and Development Center's Materials Testing Center (MTC)

    Data.gov (United States)

    Federal Laboratory Consortium — The Engineer Research and Development Center's Materials Testing Center (MTC) is committed to quality testing and inspection services that are delivered on time and...

  12. The quest for quality blood banking program in the new millennium the American way.

    Science.gov (United States)

    Kim, Dae Un

    2002-08-01

    For an industry to succeed and satisfy its customers, "QUALITY" must be a primary goal. Quality has been central to blood banking from its inception, with the evolution of a Quality Program since the opening of the first blood bank in U.S. at the Cook County Hospital in 1937. Over the ensuing decades, continuous scientific progress in blood preservation, filters, viral and blood group testing, crossmatching, automation, and computerization including bar coding, etc. has contributed to the quality and safety of the blood products and transfusion service. However, with the advent of the AIDS era, an increasingly sensitized and informed public is continuously demanding that the highest level of quality be achieved and maintained in all processes involved in providing all blood products. The Food and Drug Administration (FDA) introduced the concept of a "zero risk blood supply" as the industry goal. Furthermore, the cost containment and resource-constrained environment have changed the complexity of the quality practice. Both regulatory agencies such as the FDA, the Health Care Financing Administration [HCFA, which was recently renamed as the Centers for Medicare and Medicaid Services (CMS) in July, 2001], and the State Department of Health, and accrediting agencies, such as the American Association of Blood Banks (AABB), the College of American Pathologists (CAP), and the Joint Commission on Accreditation of Healthcare Organizations (JCAHO), require blood banks and transfusion services to establish and follow a Quality Control and Quality Assurance Program for their licensing, certification and accreditation. Every laboratory has to comply with the Clinical Laboratory Improvement Amendments of 1988 (CLIA '88) quality requirements being implemented by the CMS. The FDA guidelines assist facilities in compliance with Current Good Manufacturing Practices (cGMP). The AABB's Quality System Essentials (QSE) are based on these specifications and provide additional guidance in

  13. Hospitals report on cancer centers.

    Science.gov (United States)

    Rees, T

    2001-01-01

    Woman's Hospital, Baton Rouge, La., is first-place winner among cancer centers. Holy Cross Hospital's Michael and Dianne Bienes Comprehensive Cancer Center, Ft. Lauderdale, Fla., is named second; and, Cardinal Health System's Ball Cancer Center, Muncie, Ind., third.

  14. Defining the medical imaging requirements for a rural health center

    CERN Document Server

    2017-01-01

    This book establishes the criteria for the type of medical imaging services that should be made available to rural health centers, providing professional rural hospital managers with information that makes their work more effective and efficient. It also offers valuable insights into government, non-governmental and religious organizations involved in the planning, establishment and operation of medical facilities in rural areas. Rural health centers are established to prevent patients from being forced to travel to distant urban medical facilities. To manage patients properly, rural health centers should be part of regional and more complete systems of medical health care installations in the country on the basis of a referral and counter-referral program, and thus, they should have the infrastructure needed to transport patients to urban hospitals when they need more complex health care. The coordination of all the activities is only possible if rural health centers are led by strong and dedicated managers....

  15. An Analysis of and Recommendations for the Peruvian Blood Collection and Transfusion System

    Science.gov (United States)

    George, Paul E; Vidal, Julio; Garcia, Patricia J

    2016-01-01

    Background Peru experienced a crisis in its blood collection and supply system in the mid-2000s, as contaminated blood led to several transfusion-transmitted infections (TTI), occurring in the backdrop of extremely low voluntary donation rates and a national blood supply shortage. Thus, the Peruvian Ministry of Health (MINSA) implemented a national investigation on the safety and quality of the Peruvian blood collection/transfusion network. Methods Every Peruvian blood bank was evaluated by MINSA from 2007–2008. These evaluations consisted of an update of the national registry of blood banks and visits to each blood bank from MINSA oversight teams. Information was collected on the condition of the blood bank personnel, equipment, supplies, and practices. Further, previously-collected blood at each blood bank was randomly selected and screened for TTI-causing pathogens. Results Uncovered in this investigation was a fragmented, under-equipped, and poorly-staffed blood collection and transfusion network, consisting of 241 independent blood banks and resulting in suboptimal allocation of resources. Further, blood with evidence of TTI-causing pathogens (including Hepatitis B, Hepatitis C, and syphilis) and set for transfusion was discovered at three separate blood banks as part of the random screening process. Conclusion Using the successful reorganizations of national blood supply systems in other Latin American countries as examples, Peru would be well-served to form large, high-volume, regional blood collection and transfusion centers, responsible for blood collection and screening for the entire country. The small, separate blood banks would then be transformed into a network of blood transfusion centers, not responsible for blood collection. This reorganization would allow Peru to better utilize its resources, standardize the blood collection and transfusion process, and increase voluntary donation, resulting in a safer, more abundant national blood product.

  16. Ethnic Differences in Physical Fitness, Blood Pressure and Blood Chemistry in Women (AGES 20-63)

    Science.gov (United States)

    Ayers, G. W.; Wier, L. T.; Jackson, A. S.; Stuteville, J. E.; Keptra, Sean (Technical Monitor)

    1999-01-01

    This study examined the role of ethnicity on the aerobic fitness, blood pressure, and selected blood chemistry values of women. One hundred twenty-four females (mean age 41.37 +/- 9.0) were medically Examined at the NASA/Johnson Space Center occupational health clinic. Ethnic groups consisted of 23 Black (B), 18 Hispanic (H) and 83 Non-minority (NM). Each woman had a maximum Bruce treadmill stress test (RER greater than or = 1.1) and a negative ECG. Indirect calorimetry, skinfolds, self-report physical activity (NASA activity scale), seated blood pressure, and blood chemistry panel determined VO2max, percent fat, level of physical activity, blood pressure and blood chemistry values. ANOVA revealed that the groups did not differ (p greater than 0.05) in age, VO2 max, weight, percent fat, level of physical activity, total cholesterol, or HDL-C. However, significant differences (p greater than 0.05) were noted in BMI, diastolic blood pressure, and blood chemistries. BMI was 3.17 higher in H than in NM; resting diastolic pressures were 5.69 and 8.05 mmHg. lower in NM and H than in B; triglycerides were 48.07 and 37.21 mg/dl higher in H than in B and NM; hemoglobin was .814 gm/dl higher in NM than B; fasting blood sugar was 15.41 mg/dl higher in H than NM; The results of this study showed that ethnic groups differed in blood pressure and blood chemistry values but not aerobic fitness or physical activity. There was an ethnic difference in BMI but not percent fat.

  17. 21 CFR 864.9100 - Empty container for the collection and processing of blood and blood components.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Empty container for the collection and processing of blood and blood components. 864.9100 Section 864.9100 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Products Used In Establishments...

  18. International Water Center

    Science.gov (United States)

    The urban district of Nancy and the Town of Nancy, France, have taken the initiative of creating an International Center of Water (Centre International de l'Eau à Nancy—NAN.C.I.E.) in association with two universities, six engineering colleges, the Research Centers of Nancy, the Rhine-Meuse Basin Agency, and the Chamber of Commerce and Industry. The aim of this center is to promote research and technology transfer in the areas of water and sanitation. In 1985 it will initiate a research program drawing on the experience of 350 researchers and engineers of various disciplines who have already been assigned to research in these fields. The research themes, the majority of which will be multidisciplinary, concern aspects of hygiene and health, the engineering of industrial processes, water resources, and the environment and agriculture. A specialist training program offering five types of training aimed at university graduates, graduates of engineering colleges, or experts, will start in October 1984.

  19. Right patient, Right blood

    DEFF Research Database (Denmark)

    Selberg, Hanne; Madsen, Trine Stougaard

    2014-01-01

    Right patient, Right Blood Simulation based training in blood transfusion practice in nursing education Background: In spite of strict checking procedures to handling transfusion of blood severe adverse reactions are likely to happen and the major cause of morbidity occurs to be liable to human...... errors. Nursing students have limited possibility to practice safe blood transfusion during clinical placements. We introduced simulation-based workshops to reinforce safe transfusion practice and thus increase patient safety but equally important to bridge the gap between theory and practice. Objectives......: The objective of the current study was to test workshops focusing on procedures of safe blood transfusion by combining theory and practice, integrating current guidelines on safe blood transfusion and hereby help students to better recognize and handle errors and adverse reactions. Methods: 372 third year...

  20. Institute for Rock Magnetism established

    Science.gov (United States)

    Banerjee, Subir K.

    There is a new focal point for cooperative research in advanced rock magnetism. The University of Minnesota in Minneapolis has established an Institute for Rock Magnetism (IRM) that will provide free access to modern equipment and encourage visiting fellows to focus on important topics in rock magnetism and related interdisciplinary research. Funding for the first three years has been secured from the National Science Foundation, the W.M. Keck Foundation, and the University of Minnesota.In the fall of 1986, the Geomagnetism and Paleomagnetism (GP) section of the AGU held a workshop at Asilomar, Calif., to pinpoint important and emerging research areas in paleomagnetism and rock magnetism, and the means by which to achieve them. In a report of this workshop published by the AGU in September 1987, two urgent needs were set forth. The first was for interdisciplinary research involving rock magnetism, and mineralogy, petrology, sedimentology, and the like. The second need was to ease the access of rock magnetists and paleomagnetists around the country to the latest equipment in modern magnetics technology, such as magneto-optics or electronoptics. Three years after the publication of the report, we announced the opening of these facilities at the GP section of the AGU Fall 1990 Meeting. A classified advertisement inviting applications for visiting fellowships was published in the January 22, 1991, issue of Eos.