Lenin A Villamizar-Martinez
Full Text Available Case summary A 10-year-old castrated male domestic shorthair cat was presented for assessment of a gingival mass surrounding the left maxillary third and fourth premolar teeth. The mass was surgically removed by means of a marginal rim excision, and the tissue was submitted for histological assessment. It was identified as a benign cementoblastoma (true cementoma. There was proliferation of mineralized eosinophilic material with multiple irregularly placed lacunae and reversal lines, reminiscent of cementum. The cat recovered uneventfully from the anesthesia, and there was no evidence of tumor recurrence 6 months after surgery. Relevance and novel information Cementoblastomas (true cementomas in domestic animals are rare, with just a few reports in ruminants, monogastric herbivores and rodents. Cementoblastoma is considered a benign tumor that arises from the tooth root. The slow, expansive and constant growth that characterizes these masses may be accompanied by signs of oral discomfort and dysphagia. This case report is intended to increase knowledge regarding this tumor in cats and also highlights the importance of complete excision of the neoplasm. To our knowledge, there are no previous reports in the literature of cementoblastoma in the cat.
Mellado, J.M.; Camins, A.; Sauri, A. [Hospital Universitari de Tarragona Joan XXIII, Institut de Diagnostic per la Imatge, Tarragona (Spain); Mayayo, E. [Hospital Universitari de Tarragona Joan XXIII, Servei de Anatomia Patologica, Tarragona (Spain); Fernandez, F. [Hospital Universitario Marques de Valdecilla, Servicio de Anatomia Patologica, Santander (Spain); Perez del Palomar, L. [Pius Hospital de Valls, Servei de Radiologia, Tarragona (Spain)
Bone tumors containing fibrous tissue and cementum-like spherules are typically found in the maxilla and mandible. However, such lesions are extremely infrequent in the long bones. We report the complete radiologic assessment of a cementoma of the fibula in a 42-year-old man. We also correlate the findings with data provided by histopathologic analysis, and review the English-language literature on tumors of long bones that may contain cementum-like material. (orig.)
牙颌面锥形束CT与曲面体层X线检查对颌骨牙骨质瘤样病变诊断价值的比较研究%Comparative Studies of Diagnostic Evaluation of the Maxillary and Mandibular Cementoma Using Cone Beam Computer ized Tomography Compared with Panoramic Radiography
龙卫平; 谭跃展; 翦新春; 钟锐
Objective: To assess the osseous lesions of the maxillary and mandibular cementoma by dental cone beam computerized tomography (CBCT) and to compare it with panoramic radiography. Methods: Three patients with the maxillary and mandibular cementoma had undergone panoramic radiographic and dental come beam computerized tomographic examinations. The results were compared and the accuracy with CBCT and panoramic radiography was assessed. Results; Panoramic radiography showed sizes and scopes of the lesions in the maxilla and mandible. Cone beam computerized tomography reproduced multiple images including axial. coronal and sagittal planes of the lesions. Cone beam computerized tomography also provided a complete radiographic investigation of the cementoma in the maxilla and mandible. Conclusion: Cone beam computerized tomography is one of the best choices of imaging diagnosis of cementoma in the maxilla and mandible.%目的:比较牙颌面专用CBCT与曲面体层对颌骨牙骨质瘤的诊断价值.方法:对3例发生于上下颌骨中的牙骨质瘤患者,分别选用曲面体层和CBCT检查,并将检查结果进行比较分析,判断相互之间的一致性和差异性.结果:3例上下颌骨内牙骨质瘤病变,在曲面体层上均有显示,但CBCT检查可以在矢状位、冠状位和横断面上以多个层面准确地反映病变的位置及骨质破坏的情况.结论:CBCT在对上下颌骨牙骨质瘤的诊断较曲面体层更为有价值.
Andreeva, T V; Tyazhelova, T V; Rykalina, V N; Gusev, F E; Goltsov, A Yu; Zolotareva, O I; Aliseichik, M P; Borodina, T A; Grigorenko, A P; Reshetov, D A; Ginter, E K; Amelina, S S; Zinchenko, R A; Rogaev, E I
Tumors of the jaws may represent different human disorders and frequently associate with pathologic bone fractures. In this report, we analyzed two affected siblings from a family of Russian origin, with a history of dental tumors of the jaws, in correspondence to original clinical diagnosis of cementoma consistent with gigantiform cementoma (GC, OMIM: 137575). Whole exome sequencing revealed the heterozygous missense mutation c.1067G > A (p.Cys356Tyr) in ANO5 gene in these patients. To date, autosomal-dominant mutations have been described in the ANO5 gene for gnathodiaphyseal dysplasia (GDD, OMIM: 166260), and multiple recessive mutations have been described in the gene for muscle dystrophies (OMIM: 613319, 611307); the same amino acid (Cys) at the position 356 is mutated in GDD. These genetic data and similar clinical phenotypes demonstrate that the GC and GDD likely represent the same type of bone pathology. Our data illustrate the significance of mutations in single amino-acid position for particular bone tissue pathology. Modifying role of genetic variations in another gene on the severity of the monogenic trait pathology is also suggested. Finally, we propose the model explaining the tissue-specific manifestation of clinically distant bone and muscle diseases linked to mutations in one gene. PMID:27216912
Karöz, Tuğçe Berre; Sumer, Mahmut; Açıkgöz, Aydan; Süllü, Yurdanur
A benign cementoblastoma, which is another name for a true cementoma, is a rare neoplasm that develops from odontogenic ectomesenchyme. It is characterized by a mineralized mass attached to the apex of the root produced by neoplastic cementoblasts. More than 75% of cases arise in the mandible, with 90% of them manifesting in the molar and premolar regions. This neoplasm occurs most commonly in children and young adults, with males being affected slightly more than females. Radiographically, the tumor is observed as a well-defined radiopaque mass that is fused to a tooth root and is surrounded by a radiolucent rim. The treatment of benign cementoblastoma consists of removal of the lesion and extraction of the affected tooth. This report presents an unusual case of benign cementoblastoma in a 31-year-old female, presenting as a densely mineralized mass seen at the apex of the impacted right mandibular canine tooth on radiographs. PMID:27595092
Yoo, Seon Young; Baek, Seung Yon; Choi, Kyung Hee; Suh, Jeung Soo; Rhee, Chung Sik; Kim, Hee Seup [Ewha Womans University College of Medicine, Seoul (Korea, Republic of)
Benign tumors of the mandible are uncommon lesions. That were classified into odontogenic tumors and nonodontogenic tumors. Author reviewed the radiological evaluation and pathological microscopic finding from 33 benign tumors of the mandible that were confirmed by the biopsy during last 10 years in Dental Clinics, Ewha Womans University Hospital and Seoul National University Dental Hospital. Following results were obtained; 1. Benign tumors of the mandible were classified into odontogenic (66.7%) and non-odontogenic tumors (33.3%). 2. The range of the age distribution was between 6 years and 67 years old. The commonest age group was the second decade (39.4%). 3. There was no difference to sex distribution. 4. The most frequent location was the body of the mandible (42.4%). 5. Radiographic findings were relatively characteristic in odontogenic tumors rather than non-odontogenic tumors. 1) Radiolucent cystic lesions-ameloblastoma, odontogenic myxoma, odontogenic fibtoma, aneurysmal bone cyst and neurofibroma. 2) Radiopaque mass lesions-odontoma, cementoma and osteoma. 3) Mixed patterns-ossifying fibroma, cementifying fibroma, calcifying odontogenic epithelial tumor and hemangioma. It was concluded that the radiographic examination was of value to diagnose the benign tumors of the mandible in symptomless patients.