WorldWideScience

Sample records for cells measuring devices

  1. A microwell array device capable of measuring single-cell oxygen consumption rates

    OpenAIRE

    Molter, Timothy W.; McQuaide, Sarah C.; Suchorolski, Martin T.; Strovas, Tim J.; Burgess, Lloyd W.; Meldrum, Deirdre R.; Lidstrom, Mary E.

    2009-01-01

    Due to interest in cell population heterogeneity, the development of new technology and methodologies for studying single cells has dramatically increased in recent years. The ideal single cell measurement system would be high throughput for statistical relevance, would measure the most important cellular parameters, and minimize disruption of normal cell function. We have developed a microwell array device capable of measuring single cell oxygen consumption rates (OCR). This OCR device is ab...

  2. Novel Fouling Measurement Device

    OpenAIRE

    Sinčić, D.; Ribić, B.; Caharija, A.

    2015-01-01

    The novel device for measuring characteristics of the process that takes place when hydrocarbon liquids are subjected to elevated temperatures is described. The measuring cell has the form of a loop in which circulation is induced by a turbine stirrer. The stirrer contains magnets built into its blades, enabling mixing by a magnetic mixer positioned below the cell. No moving part protrudes from the cell. The fouling process takes place at the hot-wire probe positioned at the centre of the liq...

  3. Single cell studies of mouse embryonic stem cell (mESC) differentiation by electrical impedance measurements in a microfluidic device.

    Science.gov (United States)

    Zhou, Ying; Basu, Srinjan; Laue, Ernest; Seshia, Ashwin A

    2016-07-15

    Biological populations of cells show considerable cell-to-cell variability. Study of single cells and analysis of cell heterogeneity are considered to be critical in understanding biological processes such as stem cell differentiation and cancer development. Recent advances in lab-on-a-chip techniques have allowed single-cell capture in microfluidic channels with the possibility of precise environmental control and high throughput of experiments with minimal usage of samples and reagents. In recent years, label-free techniques such as electrical impedance spectroscopy have emerged as a non-invasive approach to studying cell properties. In this study, we have designed and fabricated a microfluidic device that combines hydrodynamic trapping of single cells in pre-defined locations with the capability of running electrical impedance measurements within the same device. We have measured mouse embryonic stem cells (mESCs) at different states during differentiation (t=0h, 24h and 48h) and quantitatively analysed the changes in electrical parameters of cells during differentiation. A marked increase in the magnitude of the cell impedance is found during cell differentiation, which can be attributed to an increase in cell size. The analysis of the measurements shows that the nucleus-to-cytoplasm ratio decreases during this process. The degree of cell heterogeneity is observed to be the highest when the cells are at the transition state (24h), compare with cells at undifferentiated (0h) and fully differentiated (48h) states. The device enables highly efficient single cell trapping and provides sensitive, label-free electrical impedance measurements of individual cells, enabling the possibility of quantitatively analysing their physical state as well as studying the associated heterogeneity of a cell population. PMID:26963790

  4. Single cell studies of mouse embryonic stem cell (mESC) differentiation by electrical impedance measurements in a microfluidic device

    Science.gov (United States)

    Zhou, Ying; Basu, Srinjan; Laue, Ernest; Seshia, Ashwin A.

    2016-01-01

    Biological populations of cells show considerable cell-to-cell variability. Study of single cells and analysis of cell heterogeneity are considered to be critical in understanding biological processes such as stem cell differentiation and cancer development. Recent advances in lab-on-a-chip techniques have allowed single-cell capture in microfluidic channels with the possibility of precise environmental control and high throughput of experiments with minimal usage of samples and reagents. In recent years, label-free techniques such as electrical impedance spectroscopy have emerged as a non-invasive approach to studying cell properties. In this study, we have designed and fabricated a microfluidic device that combines hydrodynamic trapping of single cells in pre-defined locations with the capability of running electrical impedance measurements within the same device. We have measured mouse embryonic stem cells (mESCs) at different states during differentiation (t=0 h, 24 h and 48 h) and quantitatively analysed the changes in electrical parameters of cells during differentiation. A marked increase in the magnitude of the cell impedance is found during cell differentiation, which can be attributed to an increase in cell size. The analysis of the measurements shows that the nucleus-to-cytoplasm ratio decreases during this process. The degree of cell heterogeneity is observed to be the highest when the cells are at the transition state (24 h), compare with cells at undifferentiated (0 h) and fully differentiated (48 h) states. The device enables highly efficient single cell trapping and provides sensitive, label-free electrical impedance measurements of individual cells, enabling the possibility of quantitatively analysing their physical state as well as studying the associated heterogeneity of a cell population. PMID:26963790

  5. Turnbuckle diamond anvil cell for high-pressure measurements in a superconducting quantum interference device magnetometer

    Science.gov (United States)

    Giriat, Gaétan; Wang, Weiwei; Attfield, J. Paul; Huxley, Andrew D.; Kamenev, Konstantin V.

    2010-07-01

    We have developed a miniature diamond anvil cell for magnetization measurements in a widely used magnetic property measurement system commercial magnetometer built around a superconducting quantum interference device. The design of the pressure cell is based on the turnbuckle principle in which force can be created and maintained by rotating the body of the device while restricting the counterthreaded end-nuts to translational movement. The load on the opposed diamond anvils and the sample between them is generated using a hydraulic press. The load is then locked by rotating the body of the cell with respect to the end-nuts. The dimensions of the pressure cell have been optimized by use of finite element analysis. The cell is approximately a cylinder 7 mm long and 7 mm in diameter and weighs only 1.5 g. Due to its small size the cell thermalizes rapidly. It is capable of achieving pressures in excess of 10 GPa while allowing measurements to be performed with the maximum sensitivity of the magnetometer. The performance of the pressure cell is illustrated by a high pressure magnetic study of Mn3[Cr(CN)6]2ṡxH2O Prussian blue analog up to 10.3 GPa.

  6. Kelvin Probe Measurements on Solar Cells and Other Thin Film Devices

    Science.gov (United States)

    Delk, John; Dils, D. W.; Lush, G. B.; Mackey, Willie R. (Technical Monitor)

    2001-01-01

    The Kelvin Probe (KP) has been used for years to measure the surface potential of metals and semiconductors. The KP is an elegantly simple but powerful tool invented by Lord Kelvin around the turn of the century. Using changes in surface potentials as a result of changing the intensity and wavelength of illumination, the KP returns data on material parameters such as band gap energies and the energy levels of interface states. We have employed the KP in the study of CdTe-based solar cells and quantum dot-based solar cells, as well as other thin-film devices. We hope eventually that the KP will be used as an in-line testing station for a fabrication process so that unfinished devices that will not meet requirements can be thrown out before the processing is completed, thus saving resources. Results of these studies will be presented.

  7. Development of oxide layer thickness measuring device for irradiated nuclear fuel rods in hot cell

    International Nuclear Information System (INIS)

    It has been known that water side corrosion of fuel rods in nuclear reactor is accompanied with the loss of metallic wall thickness and pickup of hydrogen. This corrosion is one of the important limiting factors in the operating life of fuel rods. In connection with the fuel cladding corrosion, a device to measure the water side oxide layer thickness by means of the eddy current method without destructing the fuel rod was developed by KAERI. The device was installed on the multi function testing bench in the nondestructive test hot cell and its calibration was carried out successfully for the standard rod attached with plastic thin films whose thicknesses are predetermined. It shows good precision within 10% error

  8. Individual Mammalian Cell Magnetic Measurements with a Superconducting Quantum Interference Device

    Science.gov (United States)

    Palmstrom, Johanna C.; Brewer, Kimberly; Tee, Sui Seng; Theis, Eric; Rutt, Brian; Moler, Kathryn A.

    2015-03-01

    Magnetism can be introduced into otherwise nonmagnetic cells by the uptake of superparamagnetic iron oxide (SPIO) nanoparticles. SPIO nanoparticles are used in numerous biomedical applications including cellular therapies and targeted drug delivery. Currently there are few tools capable of characterizing individual magnetic nanoparticles and the magnetic properties of individual mammalian cells loaded with SPIO. Our scanning superconducting quantum interference devices (SQUIDs) are good candidates for these measurements due to their high sensitivity to magnetic dipole moments (approx. 200 μb/ √Hz) In this study, we use a scanning SQUID to image the magnetic flux from SPIO loaded H1299 lung cancer cells. We find that the magnetic moment spatially varies inside the cell with each cell having a unique distribution of moments. We also correlate these magnetic images with optical and scanning electron microscope images. These results show that the SQUID is a useful tool for imaging biological magnetism. The visualization of single cell magnetism and the quantification of magnetic dipole moments in magnetically labeled cells can be used to optimize conventional biological magnetic imaging techniques, such as MRI.

  9. Radiation flux measuring device

    International Nuclear Information System (INIS)

    A radiation flux measuring device is described which employs an attenuator circuit, the output of which is maintained constant, connected to a radiation detector. Means connected to the attenuator circuit produce an output representing the log of the a-c component of the radiation detector, thereby providing a true root mean square logarithmic output

  10. Radiation flux measuring device

    International Nuclear Information System (INIS)

    A radiation flux measuring device is described which employs a differential pair of transistors, the output of which is maintained constant, connected to a radiation detector. Means connected to the differential pair produce a signal representing the log of the a-c component of the radiation detector, thereby providing a signal representing the true root mean square logarithmic output. 3 claims, 2 figures

  11. Neutron measuring device

    International Nuclear Information System (INIS)

    The device of the present invention concerns measurement for neutrons in a tokamak type thermonuclear device and it can measure total amount of generated neutrons accurately throughout the operation period even if an error is caused in counted values by plasma disruption. That is, the device comprises (1) a means for detecting presence or absence of occurrence of plasma disruption and the time for the initiation of the occurrence, (2) a first data processing means for processing detection signals, (3) a means for detecting neutrons generated in plasmas and (4) a second data processing means for calculating integrated values for the number of neutrons generated from the start to the completion of electric discharge when no disruption occurs and calculating integrated values for the number of generated neutrons from the start of electric discharge to the time at the initiation of occurrence of the disruption when disruption is present. In the thus constituted device, even if an error is caused by frequent occurrence of plasma disruption, total time integrated amount of neutrons generated in the plasmas can be measured accurately. (I.S.)

  12. A power measuring device

    International Nuclear Information System (INIS)

    As a part of the klystron test facility of the Dutch NIKHEF-K accelerator, a sensitive power measuring device has been built. The high-frequency power of a klystron is stored in a water-cooled dummy load. Using a microcomputer, the increase of the water temperature and the water flow rate are transformed to a digital indication of the klystron power. (Auth.)

  13. Reactor power measuring device

    International Nuclear Information System (INIS)

    The device of the present invention efficiently calibrates a fixed type gamma ray thermometer of a reactor power measuring device of a BWR type reactor. Namely, the device of the present invention calculates peripheral fuel rod power distribution by calibrating the reactor power distribution by heat generation amount, the reactor power distribution being obtained by a calculation based on a reactor model for converting the signals of a plurality of the gamma ray thermometers in the reactor core based on a conversion formula. In this case, the conversion formula is a relational formula between the power of a thermocouple of the gamma ray thermometer, gamma ray heat generation amount, thermocouple zero power sensitivity relative to a temperature coefficient. A conversion efficient calculation means makes a calibration heater to generate heat at a predetermined power, and the thermocouple zero power sensitivity and the temperature coefficient are obtained based on the output of the gamma ray thermometer in this case. The calibration means updates to conversion type thermocouple zero power sensitivity and temperature coefficient. A calibration execution means executes the operations described above successively, and when the thermocouple zero power sensitivity and the temperature coefficient are out of an allowable range, the means informs it and eliminates the corresponding gamma ray thermometer from the measuring meters. (I.S.)

  14. PolyMUMPs MEMS device to measure mechanical stiffness of single cells in aqueous media

    International Nuclear Information System (INIS)

    A method of experimentally determining the mechanical stiffness of single cells by using differential displacement measurements in a two stage spring system is presented. The spring system consists of a known MEMS reference spring and an unknown cellular stiffness: the ratio of displacements is related to the ratio of stiffness. A polyMUMPs implementation for aqueous media is presented and displacement measurements made from optical microphotographs using a FFT based displacement method with a repeatability of ∼20 nm. The approach was first validated on a MEMS two stage spring system of known stiffness. The measured stiffness ratios of control structures (i) MEMS spring systems and (ii) polystyrene microspheres were found to agree with theoretical values. Mechanical tests were then performed on Saccharomyces cerevisiae (Baker’s yeast) in aqueous media. Cells were placed (using a micropipette) inside MEMS measuring structures and compressed between two jaws using an electrostatic actuator and displacements measured. Tested cells showed stiffness values between 5.4 and 8.4 N m−1 with an uncertainty of 11%. In addition, non-viable cells were tested by exposing viable cells to methanol. The resultant mean cell stiffness dropped by factor of 3 × and an explicit discrimination between viable and non-viable cells based on mechanical stiffness was seen. (paper)

  15. Reactor power measuring device

    International Nuclear Information System (INIS)

    The present invention provides a self-powered long detector having a sensitivity over the entire length of a reactor core as an entire control rod withdrawal range of a BWR type reactor, and a reactor power measuring device using a gamma ray thermometer which scarcely causes sensitivity degradation. That is, a hollow protection pipe is disposed passing through the reactor core from the outside of a reactor pressure vessel. The self-powered long detectors and the gamma ray thermometers are inserted and installed in the protection pipe. An average reactor power in an axial direction of the reactor relative to a certain position in the horizontal cross section of the reactor core is determined based on the power of the self-powered long detector over the entire length of the reactor core. Since the response of the self-powered detector relative to a local power change is rapid, the output is used as an input signal to a safety protection device of the reactor core. Further, a gamma ray thermometer secured in the reactor and having scarce sensitivity degradation is used instead of an incore travelling neutron monitor used for relative calibration of an existent neutron monitor secured in the reactor. (I.S.)

  16. Power distribution measuring device

    International Nuclear Information System (INIS)

    The present invention concerns a device for measuring power distribution of neutrons in a nuclear reactor. That is, a gamma thermometer used so far has drawbacks of slow time response and low sensitivity although it is not always necessary to use a movable incore detector for calibration. However, the device of the present invention compensates the drawback by incorporating a gamma thermometer and an another incore detector of a different type in an identical detector assembly. The gamma thermometer is calibrated by an electric heater. With such a constitution, the sensitivity calibration of the detector of different type incorporated in the identical detector assembly can be conducted without relying on a movable detector when the reactor is stable. Further, if the detector of the different type having rapid response, such as a fission ionization chamber or a self-powered type detector is used as a detector, a reactor core power distribution monitoring system of rapid time response can be attained. (I.S.)

  17. Microfluidic Cell Culture Device

    Science.gov (United States)

    Takayama, Shuichi (Inventor); Cabrera, Lourdes Marcella (Inventor); Heo, Yun Seok (Inventor); Smith, Gary Daniel (Inventor)

    2014-01-01

    Microfluidic devices for cell culturing and methods for using the same are disclosed. One device includes a substrate and membrane. The substrate includes a reservoir in fluid communication with a passage. A bio-compatible fluid may be added to the reservoir and passage. The reservoir is configured to receive and retain at least a portion of a cell mass. The membrane acts as a barrier to evaporation of the bio-compatible fluid from the passage. A cover fluid may be added to cover the bio-compatible fluid to prevent evaporation of the bio-compatible fluid.

  18. Optical diffraction tomography using a digital micromirror device for stable measurements of 4D refractive index tomography of cells

    Science.gov (United States)

    Shin, Seungwoo; Kim, Kyoohyun; Kim, Taeho; Yoon, Jonghee; Hong, Kihyun; Park, Jinah; Park, YongKeun

    2016-03-01

    Optical diffraction tomography (ODT) is an interferometric microscopy technique capable of measuring 3-D refractive index (RI) distribution of transparent samples. Multiple 2-D holograms of a sample illuminated with various angles are measured, from which 3-D RI map of the sample is reconstructed via the diffraction theory. ODT has been proved as a powerful tool for the study of biological cells, due to its non-invasiveness, label-free and quantitative imaging capability. Recently, our group has demonstrated that a digital micromirror device (DMD) can be exploited for fast and precise control of illumination beams for ODT. In this work, we systematically study the precision and stability of the ODT system equipped with a DMD and present measurements of 3-D and 4-D RI maps of various types of live cells including human red blood cells, white blood cells, hepatocytes, and HeLa cells. Furthermore, we also demonstrate the effective visualization of 3-D RI maps of live cells utilizing the measured information about the values and gradient of RI tomograms.

  19. Optical diffraction tomography using a digital micromirror device for stable measurements of 4-D refractive index tomography of cells

    CERN Document Server

    Shin, Seungwoo; Kim, Taeho; Yoon, Jonghee; Hong, Kihyun; Park, Jinah; Park, YongKeun

    2016-01-01

    Optical diffraction tomography (ODT) is an interferometric microscopy technique capable of measuring 3-D refractive index (RI) distribution of transparent samples. Multiple 2-D holograms of a sample illuminated with various angles are measured, from which 3-D RI map of the sample is reconstructed via the diffraction theory. ODT has been proved as a powerful tool for the study of biological cells, due to its non-invasiveness, label-free and quantitative imaging capability. Recently, our group has demonstrated that a digital micromirror device (DMD) can be exploited for fast and precise control of illumination beams for ODT. In this work, we systematically study the precision and stability of the ODT system equipped with a DMD and present measurements of 3-D and 4-D RI maps of various types of live cells including human red blood cells, white blood cells, hepatocytes, and HeLa cells. Furthermore, we also demonstrate the effective visualization of 3-D RI maps of live cells utilizing the measured information abou...

  20. Reactor power measuring device

    International Nuclear Information System (INIS)

    The device of the present invention comprises a γ-thermometer disposed in a BWR type reactor, a first amplifier for amplifying the output thereof, a fission ionization chamber disposed in the reactor separately from the γ-thermometer, a second amplifier for amplifying the output thereof, a differential circuit for differentiating the output signal of the second amplifier and a first adding circuit for adding an output signal of the differential circuit and an output signal of the first amplifier. Alternatively, a γ-ray self-powered neutron detector may be disposed instead of the fission ionization chamber. A second adding circuit is also disposed for adding the output signals of plurality of differentiation circuits and inputting the result to the first adding circuit. A sensitivity controller is disposed upstream of the first adder for controlling the sensitivity of the fission ionization chamber. Then, even if time delay should be caused in the γ-thermometer, output signals with good time response characteristic can be obtained by using signals of LPRM or SPND, and currently changing output of the reactor can be measured accurately to provide an effect on the improvement of the safety and operation controllability of the reactor. (N.H.)

  1. Optical device for straightness measurement

    Science.gov (United States)

    Vekteris, Vladas; Jurevicius, Mindaugas; Turla, Vytautas

    2015-11-01

    The present paper describes the research of the optical device for two-dimensional straightness measurement of technological machines. Mathematical study of an optical device, operating on the phase principle and measuring transversal displacements of machine parts in two directions ( X and Y) during their linear longitudinal motion in a machine (alongside the Z axis), is presented. How to estimate the range of travel along the Z axis is analytically shown. At this range, the measurer gives correct measurements of transverse displacement. The necessary distance from the objective focus to the image plane was defined mathematically. The sample results of measuring the displacement of the table of a technological machine by using the optical device are presented in the paper. This optical device for non-contact straightness measurement can be used for measurement straightness in turning, milling, drilling, grinding machines and other technological machines, also in geodesy and cartography, and for moving accuracy testing of mechatronic devices, robotics and others.

  2. Device for calorimetric measurement

    Science.gov (United States)

    King, William P; Lee, Jungchul

    2015-01-13

    In one aspect, provided herein is a single crystal silicon microcalorimeter, for example useful for high temperature operation and long-term stability of calorimetric measurements. Microcalorimeters described herein include microcalorimeter embodiments having a suspended structure and comprising single crystal silicon. Also provided herein are methods for making calorimetric measurements, for example, on small quantities of materials or for determining the energy content of combustible material having an unknown composition.

  3. Optoelectronic device for hematocrit measurements

    Science.gov (United States)

    Pluta, M.; Milewska, D.; Mazikowski, A.

    2015-09-01

    An optoelectronic system for measurements of hematocrit level (HCT) in the whole human blood is presented. Proposed system integrates a dedicated optoelectronic sensor, a microcontroller and a small LCD display in a low cost, battery-powered, handheld device. Chosen method for determining blood hematocrit level is based on optical properties of whole blood in visible and NIR wavelength range. Measurements with the use of proposed system require blood samples (small drop in the range of microliters) which is placed in the micro cuvette. Then, absorption of the sample is measured at wavelengths of 570 nm and 880 nm. Prototype of the device was build and tested. Test results confirmed proper operation of the device with correct metrological parameters in application to HCT level measurements. Such a portable device can be used as a tool of bedside diagnosis, which becomes interesting alternative to full laboratory tests.

  4. Measuring verification device error rates

    International Nuclear Information System (INIS)

    A verification device generates a Type I (II) error when it recommends to reject (accept) a valid (false) identity claim. For a given identity, the rates or probabilities of these errors quantify random variations of the device from claim to claim. These are intra-identity variations. To some degree, these rates depend on the particular identity being challenged, and there exists a distribution of error rates characterizing inter-identity variations. However, for most security system applications we only need to know averages of this distribution. These averages are called the pooled error rates. In this paper the authors present the statistical underpinnings for the measurement of pooled Type I and Type II error rates. The authors consider a conceptual experiment, ''a crate of biased coins''. This model illustrates the effects of sampling both within trials of the same individual and among trials from different individuals. Application of this simple model to verification devices yields pooled error rate estimates and confidence limits for these estimates. A sample certification procedure for verification devices is given in the appendix

  5. Development of measurement device for evaluation of solar cell module output. 2; Taiyo denchi module shutsuryoku hyokayo sokuteiki no kaihatsu. 2

    Energy Technology Data Exchange (ETDEWEB)

    Minoda, M.; Itsumi, J. [Kumamoto Institute of Technology, Kumamoto (Japan)

    1996-10-27

    Enhancement in design efficiency may be attained as well as utilization in maintenance if on-the-spot data is made available, for the purpose of flexibly dealing with changes in design or matching with a house structure, in calculating the power generation output of a solar cell (PV) module. Under the circumstances, a small-sized compound measuring device was produced as a prototype which, using an I-V curve tracer, measured output and condition of a roof at the time of installation, compared with the optimum operation and predicted the power generation. The device was structured with the main body consisting of a computing part, measurement controller and power supply and with various sensor modules. The electron load control method was employed in order to measure I-V characteristics of the PV module, since it was desirable to use a variable load and to cover the range from the release voltage of a solar cell to the short-circuit state through the maximum output point. The reference module method was used for the system evaluation. The device was presumably applicable to a PV system design by incorporating a sensor module for measuring design environment data, which was essential at the time of a system design, in addition to those for measuring output. 9 refs., 4 figs., 3 tabs.

  6. New devices for radon measurements

    International Nuclear Information System (INIS)

    This work includes the description of two new devices for radon surveys developed by the authors and produced in Kazakhstan. The first appliance is 'Ramon-Radon-01' used to measure 222Rn radon in various mediums such as air, water, soil, and radon exhalation. The major advantage of the appliance lies in the absence of radioactive pollution in it after measurements. The appliances widely used in the CIS such as 'RAA-01', 'Alpharad' (produced by 'MTM Zaschita', Russia) and 'Alphaguard' (Germany) take samples directly to the measuring camera. For instance, the activity concentration of samples after they are taken by 'RAA-01' and 'Alpharad' is measured by means of electrostatic precipitation of RaA (218 Po) atoms to the square of semiconductor detector with subsequent registration of RaA alpha decay. The obvious disadvantage is that the subsequent measurement of relatively small 222Rn activity concentration values after great values of 222Rn activity concentration have been obtained requires a considerable exposure of the appliance sometimes exceeding 10 hours. Therefore, appliances register a relatively low value of the top measurement range of 20 KBq/m3. 'Alphaguard' has similar limitation resulting from precipitation of radon daughter decay products on the walls of ionizing chamber where radon activity concentration is measured. The radioactive lag of 'RAA-01', 'Alpharad' and 'Alphaguard' makes them of little use as well for automatic monitoring in the conditions of abruptly time negative derivatives on change of radon activity concentration. The second advantage is that 'Ramon-Radon-01', as opposed to above described appliances, registers almost zero radioactive lag, thanks to its constructive peculiarities which enable an abrupt increase of top range of measured value up to 5x105 Bq/m3, only limited by velocity of electron units of the appliance. The third advantage is that measurement discontinuity is determined only by time of full measurement cycle adding up

  7. Flow rate measuring devices for gas flows

    Science.gov (United States)

    Bonfig, K. W.

    1985-07-01

    Flowrate measuring devices are described: volume meter with fixed or mobile walls; turbine meter; throttling procedure; ultrasonic and Doppler methods; vortex method; rotary flowmeter; and swinging body flow measuring procedure. Flowrate can also be measured from the force exerted on bodies immersed in a fluid or based on thermodynamical principles. The characteristics and operating envelope of each device/method are given.

  8. New Devices for Electret Measurement

    OpenAIRE

    ROMANIUC Ilie

    2013-01-01

    Green energy research have increased in recent decades and interest in unconventional energy production systems is becoming more pronounced. Such unconventional energy generation system is alsobased on electret generator. The electret, is a dielectric material that has a quasi-permanent electric charge. This paper, provides a brief history of the Carnauba wax electret, will be described the process of electret making and will be presented two devices formeasuring the carnauba wax electrets, o...

  9. Zero G Mass Measurement Device (ZGMMD) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Zero Gravity Mass Measurement Device (ZGMMD) provides the ability to measure the mass of samples in a microgravity environment, like that found on the...

  10. Programmed device for coordinate measuring mechanisms

    International Nuclear Information System (INIS)

    The programmed device providing the automatic measurement of the coordinate of a continuously travelling carriage with stepwise control of the pitch and measurement range in wide limits is described. The matching of measured points at the direct and return travels of the carriage is within 50 mcm. The device was developed to automize the measurement of charged particles tracks by means of floating-wire method. It may be also used in different recorders

  11. DIMENSION MEASURING OPTICAL SIGHTING DEVICE

    Science.gov (United States)

    Kerr, G.E.

    1959-08-01

    A sighting device to check the uniformity of thickness of a lining applied to a container is presented. The sighting devlce comprises two tubular members having their ends in threaded connection with one another and a lens lying within the outer end of one of the tubular members. A ground glass inscribed with two concentric circles is located at the outer end of the other tubular section so that the image of the circular junctures, with and without the lining at the closed end of the container, can be focused on the proper circle inscribed in the ground glass so as to determine whether the lining has uniformity and whether there are thin spots.

  12. Improvements in backscatter measurement devices

    International Nuclear Information System (INIS)

    Improvements in measuring the thickness of a coating on a substrate by the technique of backscattered particles are described. These improvements enable the measurements to be carried out continuously as an integral part of the coating production line and also permit measurements where the coated elements are separated from one another by a predetermined distance. The former is achieved by situating the backscatter probe and detector on the rim of the measurement wheel and rotating this wheel at a speed such that the coated element and probe are stationary relative to one another. The latter improvement is achieved by an indexing apparatus which automatically positions the probe beside a coated element. (U.K.)

  13. Inter-device reliability of DSI measurement.

    Science.gov (United States)

    Aichinger, Philipp; Feichter, Felicitas; Aichstill, Birgitta; Bigenzahn, Wolfgang; Schneider-Stickler, Berit

    2012-12-01

    The Dysphonia Severity Index (DSI) is a measure that quantifies the overall vocal quality. The aim of the study is to evaluate the reliability of DSI measurements. The DSIs of 30 subjects were therefore measured using LingWAVES (WEVOSYS) and DiVAS (XION). To evaluate the inter-device reliability of DSI measurement, the devices' results were compared for each subject. The DSI values of both devices showed great differences. The calculated DSI differences of 95% of the subjects were within the limits of +2.39 and -2.82, which makes a clinical interpretation of severity of voice disorder using different devices questionable. The technical and procedural aspects of measurement divergences are discussed, and the need to define hardware and software standards is shown. PMID:22702894

  14. PORTABLE DEVICE FOR MEASURING SEDIMENT RESUSPENSION

    Science.gov (United States)

    A portable device for measuring sediment resuspension has been developed. he device consists of a cylindrical chamber inside of which a horizontal grid oscillates vertically. he sediments whose properties are to be determined are placed at the bottom of the chamber with water ove...

  15. Zero G Mass Measurement Device (ZGMMD) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Zero G Mass Measurement Device (ZGMMD) will provide the ability to quantify the mass of objects up to 2,000 grams, including live animal specimens in a zero G...

  16. Development of a Novel Solar Radiation Measuring Device

    OpenAIRE

    Samer Alsadi; Tamer Khatib; Sulafa Mallooh

    2012-01-01

    In this paper, a novel solar radiation measuring device is proposed. A solar cell, PIC controller, temperature sensors as well as a memory chip are used. The proposed device measures the solar radiation and the ambient temperature through a specific time period and then the measured data is stored on a memory chip through the PIC controller. After that the stored data can be transferred to a computer in order to be analyzed. However, a calibration of the used solar cell is done first, in orde...

  17. Pneumatic servo-controlled fracture resistance measuring device (PSFM-device) and contact electric resistance measuring device (CER device)

    International Nuclear Information System (INIS)

    A pneumatic servo-controlled fracture resistance measuring device can be used to test small pre cracked three point bend specimens in high temperature aqueous solutions. As the moving parts that penetrate the pressure boundary are not needed, the friction force at the sealing element location is avoided. Therefore the load control is more accurate than with the conventional servo-hydraulic devices. This enables testing of small size samples which is an advantage e.g. when testing irradiated materials and especially in determining environmentally assisted crack growth rate of structural materials. Furthermore, the new design enables simultaneous testing of several samples, which helps in producing of statistically more reliable data in a more economical way. The newly developed measuring device was used to determine fracture resistance curves for sensitized AISI 304 stainless steel, AISI 316 stainless steel and Inconel weld materials. The test environment was BWR (Boiling Water Reactor) coolant in a recirculation loop and the test type was constant displacement rate test (rising load) with displacement rates of 1.2 10-5 mm/min and 1.2 10-6 mm/min. The momentary crack growth during the tests was measured with the PD (potential drop) technique. The preliminary tests with pneumatically powered CER (Contact Electric Resistance) equipment is presented. The main parts and preliminary test results of pneumatically powered CER measuring are presented. The equipment was tested in air at room temperature and under typical BWR environments (author) (ml)

  18. A comparison of 'radon' measurement devices

    International Nuclear Information System (INIS)

    For the indoor concentration measurement of Rn decay chain members, instruments ranging from long-term integrating passive devices to far more sensitive active devices with good time resolution are in use. The former are used mainly to screen for potentially high exposure locations, while the latter are useful for assessing the exposure dynamics of encumbered premises, with potential clarification (modelling) for optimal remediation, before, during and after such process. Concentration measurement of any one decay chain member always involves its complete decay chain. The 222Rn gas concentration can be measured with gas measuring devices or with spectrometric measuring instruments that concentrate the decay products. The latter generally offer far more accurate measurement per time of the 222Rn concentration, than mere Rn gas measuring devices, and also give the decay product concentrations and thus activity ratios which are related to air exchange. The concentrations of the unattached Rn decay products may be measured simultaneously with inline screen measurement. In premises steady state ventilation conditions are rare. Rapidly changing concentrations can be measured more accurately with the more sensitive concentrating instruments - the inherent instrumental time lag of detected signals from chain decay, relative to time of sampling, should however be corrected where rates of concentration change approximate chain decay constants. Counting of beta-signals in addition to alpha-spectrometry, and quasi-continuous sampling while continuously measuring, enhances the sensitivity, and particularly measurement time lag correction, where concentration ratios are sought for elucidating air exchange. Appropriate software ought to be made available to evaluate the spectrometric data and to link it to suitable compartment ventilation models (automatic adjustment for a dynamic change in alpha-calibration could be incorporated) - this would constitute the modern version of the

  19. Presentation of a new BRDF measurement device

    Science.gov (United States)

    Serrot, Gerard; Bodilis, Madeleine; Briottet, Xavier; Cosnefroy, Helene

    1998-12-01

    The bi-directional reflectance distribution function (BRDF) plays a major role to evaluate or analyze signals reflected by Earth in the solar spectrum. A BRDF measurement device that covers a large spectral and directional domain was recently developed by ONERA/DOTA. It was designed to allow both laboratory and outside measurements. Its main characteristics are a spectral domain: 0.42-0.95 micrometers ; a geometrical domain: 0-60 degrees for zenith angle, 0-180 degrees for azimuth; a maximum target size for nadir measurements: 22 cm. For a given zenith angle of the source, the BRDF device needs about seven minutes to take measurements for a viewing zenith angle varying from 0-60 degrees and relative azimuth angle varying from 0-180 degrees. The performances, imperfections and properties of each component of the measurement chain are studied. A part of the work was devoted to characterize precisely the source, and particularly the spatial variability of the irradiance at the target level, the temporal stability and the spectral profile of the lamp. Some of these imperfections are modeled and taken into account in corrections of BRDF measurements. Concerning the sensor, a calibration in wavelength was done. Measurements of bi- directional reflectance of which is well known. A software was developed to convert all the raw data acquired automatically into BRDF values. To illustrate measurements taken by this device, some results are also presented here. They are taken over sand and short grass, for different wavelengths and geometrical conditions.

  20. Measurement-device-independent quantum key distribution.

    Science.gov (United States)

    Lo, Hoi-Kwong; Curty, Marcos; Qi, Bing

    2012-03-30

    How to remove detector side channel attacks has been a notoriously hard problem in quantum cryptography. Here, we propose a simple solution to this problem--measurement-device-independent quantum key distribution (QKD). It not only removes all detector side channels, but also doubles the secure distance with conventional lasers. Our proposal can be implemented with standard optical components with low detection efficiency and highly lossy channels. In contrast to the previous solution of full device independent QKD, the realization of our idea does not require detectors of near unity detection efficiency in combination with a qubit amplifier (based on teleportation) or a quantum nondemolition measurement of the number of photons in a pulse. Furthermore, its key generation rate is many orders of magnitude higher than that based on full device independent QKD. The results show that long-distance quantum cryptography over say 200 km will remain secure even with seriously flawed detectors. PMID:22540686

  1. Measurement device independent quantum key distribution

    CERN Document Server

    Lo, Hoi-Kwong; Qi, Bing

    2011-01-01

    How to remove detector side channel attacks has been a notoriously hard problem in quantum cryptography. Here, we propose a simple solution to this problem---*measurement* device independent quantum key distribution. It not only removes all detector side channels, but also doubles the secure distance with conventional lasers. Our proposal can be implemented with standard optical components with low detection efficiency and highly lossy channels. In contrast to the previous solution of full device independent QKD, the realization of our idea does not require detectors of near unity detection efficiency in combination with a qubit amplifier (based on teleportation) or a quantum non-demolition measurement of the number of photons in a pulse. Furthermore, its key generation rate is many orders of magnitude higher than that based on full device independent QKD. The results show that long-distance quantum cryptography over say 200km will remain secure even with seriously flawed detectors.

  2. Radiation detector device for measuring ionizing radiation

    International Nuclear Information System (INIS)

    The device contains a compensating filter circuit, which guarantees measurement of the radiation dose independent of the energy or independent of the energy and direction. The compensating filter circuit contains a carrier tube of a slightly absorbing metal with an order number not higher than 35, which surrounds a tubular detector and which carries several annular filter parts on its surface. (orig./HP)

  3. Coherence measurement with digital micromirror device.

    Science.gov (United States)

    Partanen, Henri; Turunen, Jari; Tervo, Jani

    2014-02-15

    We measure the complex-valued spatial coherence function of a multimode broad-area laser diode using Young's classical double slit experiment realized with a digital micromirror device. We use this data to construct the coherent modes of the beam and to simulate its propagation before and after the measurement plane. When comparing the results to directly measured intensity profiles, we find excellent correspondence to the extent that even small details of the beam can be predicted. We also consider the number of measurement points required to model the beam with sufficient accuracy. PMID:24562271

  4. Performance of an in-plane detection cell with integrated waveguides for UV/Vis absorbance measurements on microfluidic separation devices

    DEFF Research Database (Denmark)

    Petersen, Nickolaj Jacob; Mogensen, Klaus Bo; Kutter, Jörg Peter

    2002-01-01

    A microfluidic device with integrated waveguides and a long path length detection cell for UV/Vis absorbance detection is presented. The 750 mum U-cell detection geometry was evaluated in terms of its optical performance as well as its influence on efficiency for electrophoretic separations in the...... microdevice. Stray light was found to have a strong effect on both, the sensitivity of the detection and the available linear range. The long path length U-cell showed a 9 times higher sensitivity when compared to a conventional capillary electrophoresis (CE) system with a 75 mum inner diameter (ID) capillary...

  5. Reactor power measuring method and device therefor

    International Nuclear Information System (INIS)

    The present invention concerns measurement of a BWR type reactor power and provides a method of and a device for ensuring accuracy of calibration of sensitivity of neutron detectors and measurement of reactor power even if γ-ray thermometers are failed. Namely, the output signals of the γ-ray thermometers are compared with previously determined judging values to detect failures. The reactor power is measured based on the signals of neutron detectors calibrated by integral thermometers except for neutron detectors calibrated by γ-ray thermometers detected as failed. Calibration for sensitivity of neutron detectors as objects of γ-ray thermometers detected as failed is preferably prohibited. Accuracy of measurement of the reactor power can be ensured by the method described above. If axial power distribution of the reactor core is measured while eliminating the signals of γ-ray thermometers detected as failed, accuracy of the measurement of axial power distribution can be ensured. (N.H.)

  6. 21 CFR 882.1550 - Nerve conduction velocity measurement device.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Nerve conduction velocity measurement device. 882... conduction velocity measurement device. (a) Identification. A nerve conduction velocity measurement device is a device which measures nerve conduction time by applying a stimulus, usually to a...

  7. Device and method for measuring grid

    International Nuclear Information System (INIS)

    This rotating and displaceable device for measuring the external dimensions of polygonal transverse cross-section such a grid of nuclear assembly, has a probe rotating about an axis parralel to the axis of the grid, two ultrasonic emitters and receivers on the probe and a system turning the probe until the emitters and receipters lie a line perpendicular to the axis of the grid

  8. Whole Blood Cell Staining Device

    Science.gov (United States)

    Sams, Clarence F.; Clift, Vaughan L.; McDonald, Kelly E.

    2000-01-01

    An apparatus and method for staining particular cell markers is disclosed. The apparatus includes a flexible tube that is reversibly pinched into compartments with one or more clamps. Each compartment of the tube contains a separate reagent and is in selective fluid communication with adjoining compartments.

  9. Cell Biology Apps for Apple Devices

    OpenAIRE

    Stark, Louisa A.

    2012-01-01

    Apps for touch-pad devices hold promise for guiding and supporting learning. Students may use them in the classroom or on their own for didactic instruction, just-in-time learning, or review. Since Apple touch-pad devices (i.e., iPad and iPhone) have a substantial share of the touch-pad device market (Campbell, 2012), this Feature will explore cell biology apps available from the App Store. My review includes iPad and iPhone apps available in June 2012, but does not include courses, lectures,...

  10. MEASUREMENT OF VPN PENFORMANCE BETWEEN DIFFERENT DEVICES

    OpenAIRE

    Guo, Chao

    2013-01-01

    Network is becoming more and more important in daily life, the security is most critical issue in networking, however, when you add some security feature on your device, it will cost the resource, in this article we will test and measure how the VPN effect to your network. You can see from this article about the history of Internet and VPN, the architecture of VPN, how it works, and what kind of crypto algorithms VPN uses. The last one and also the most important of this article is the perfor...

  11. Microfluidic device for acoustic cell lysis

    Energy Technology Data Exchange (ETDEWEB)

    Branch, Darren W.; Cooley, Erika Jane; Smith, Gennifer Tanabe; James, Conrad D.; McClain, Jaime L.

    2015-08-04

    A microfluidic acoustic-based cell lysing device that can be integrated with on-chip nucleic acid extraction. Using a bulk acoustic wave (BAW) transducer array, acoustic waves can be coupled into microfluidic cartridges resulting in the lysis of cells contained therein by localized acoustic pressure. Cellular materials can then be extracted from the lysed cells. For example, nucleic acids can be extracted from the lysate using silica-based sol-gel filled microchannels, nucleic acid binding magnetic beads, or Nafion-coated electrodes. Integration of cell lysis and nucleic acid extraction on-chip enables a small, portable system that allows for rapid analysis in the field.

  12. Methods of radon measurement and devices

    International Nuclear Information System (INIS)

    The following topics and instrumentation are discussed: The quantity to be measured; Active measurement methods (scintillation cells, ionisation chambers, electrostatic collection of decay products); Passive measurement methods (charcoal detectors; electret ion chambers; etched track detectors); and Detector considerations for large-scale surveys ('always on' or 'switchable' detectors?; response to radon-220; avoidance of electrostatic effects; quality assurance for passive radon detectors; quality control within the laboratory; external quality assurance; detectors need to be easily deliverable). It is concluded that the ideal detector for large scale surveys of radon in houses is a small, closed detector in a conducting holder which excludes radon-220, supported by rigorous quality assurance procedures. (P.A.)

  13. Preliminary design of a new device to measure muscle function.

    Science.gov (United States)

    Lind, Jeffrey; Durfee, William

    2015-08-01

    A description and early results are presented for a novel device to estimate the torque-angle and torque-angular velocity properties of the quadriceps muscle group using electrical stimulation. The device straps to the shin and is moved by the operator while pulses of stimulation are applied to the motor point of the quadriceps. During stimulation, the operator raises and lowers the leg to the desired angle, and also can oscillate the leg to generate a rich velocity profile. The resulting muscle force is measured by a load cell contained in the device. In a preliminary study using 11 healthy subjects, normalized torque-angle and torque-velocity data for the quadriceps were consistent with literature results that used maximum voluntary contraction methods. PMID:26737540

  14. 46 CFR 154.1340 - Temperature measuring devices.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Temperature measuring devices. 154.1340 Section 154.1340... Instrumentation § 154.1340 Temperature measuring devices. (a) Each cargo tank must have devices that measure the temperature: (1) At the bottom of the tank; and (2) Near the top of the tank and below the maximum...

  15. A simple measuring device for laboratory indentation tests on cartilage.

    Science.gov (United States)

    Koeller, Wolfgang; Kunow, Julius; Ostermeyer, Oliver; Stomberg, Peter; Boos, Carsten; Russlies, Martin

    2008-04-01

    Mechanical testing of articular cartilage and repair tissue enables judgment of their capacity in withstanding mechanical loading. In the past, different methods have been developed requiring a complex technical setup and extensive data analysis. Therefore, the aim of the present project was to build up a simple measuring apparatus for laboratory indentation tests. The device consists of an incremental optical displacement transducer with a sleeve bearing guided plunger and a spherical tip made of polished steel (radius: 0.75 or 1.5 mm), a sensitive load cell and a stiff frame. The indentation force results from the plunger's gravity plus the force of the spring inside the displacement transducer and levels at 0.170 N or 0.765 N. The displacement transducer is fixed to the frame via the load cell that enables one to detect the initial contact of the tip with the tissue. The load cell has a standard uncertainty of 2 mN and the displacement transducer of 1 microm. From indentation-creep tests, a "0.25-s elastic modulus" is calculated. Measurements on thin rubber sheets were carried out to determine the quality of the measuring device. Compression tests on cylinders made of these rubber sheets yielded control data, and a good agreement with the "0.25-s elastic modulus" was found. Indentation tests on cartilage at different sites of sheep femoral condyles yielded a very good repeatability of the measurement results (+/-7.5%). PMID:18979621

  16. Cell biology apps for Apple devices.

    Science.gov (United States)

    Stark, Louisa A

    2012-01-01

    Apps for touch-pad devices hold promise for guiding and supporting learning. Students may use them in the classroom or on their own for didactic instruction, just-in-time learning, or review. Since Apple touch-pad devices (i.e., iPad and iPhone) have a substantial share of the touch-pad device market (Campbell, 2012), this Feature will explore cell biology apps available from the App Store. My review includes iPad and iPhone apps available in June 2012, but does not include courses, lectures, podcasts, audiobooks, texts, or other books. I rated each app on a five-point scale (1 star = lowest; 5 stars = highest) for educational and production values; I also provide an overall score. PMID:22949420

  17. Measurement-device-independent quantum coin tossing

    Science.gov (United States)

    Zhao, Liangyuan; Yin, Zhenqiang; Wang, Shuang; Chen, Wei; Chen, Hua; Guo, Guangcan; Han, Zhengfu

    2015-12-01

    Quantum coin tossing (QCT) is an important primitive of quantum cryptography and has received continuous interest. However, in practical QCT, Bob's detectors can be subjected to detector-side channel attacks launched by dishonest Alice, which will possibly make the protocol completely insecure. Here, we report a simple strategy of a detector-blinding attack based on a recent experiment. To remove all the detector side channels, we present a solution of measurement-device-independent QCT (MDI-QCT). This method is similar to the idea of MDI quantum key distribution (QKD). MDI-QCT is loss tolerant with single-photon sources and has the same bias as the original loss-tolerant QCT under a coherent attack. Moreover, it provides the potential advantage of doubling the secure distance for some special cases. Finally, MDI-QCT can also be modified to fit the weak coherent-state sources. Thus, based on the rapid development of practical MDI-QKD, our proposal can be implemented easily.

  18. Guidelines on calibration of neutron measuring devices

    International Nuclear Information System (INIS)

    The International Atomic Energy Agency and the World Health Organization have agreed to establish an IAEA/WHO Network of Secondary Standard Dosimetry Laboratories (SSDLs) in order to improve accuracy in applied radiation dosimetry throughout the world. These SSDLs must be equipped with, and maintain, secondary standard instruments, which have been calibrated against primary standards, and must be nominated by their governments for membership of the network. The majority of the existing SSDLs were established primarily to work with photon radiation (X-rays and gamma rays). Neutron sources are, however, increasingly being applied in industrial processes, research, nuclear power development and radiation biology and medicine. Thus, it is desirable that the SSDLs in countries using neutron sources on a regular basis should also fulfil the minimum requirements to calibrate neutron measuring devices. It is the primary purpose of this handbook to provide guidance on calibration of instruments for radiation protection. A calibration laboratory should also be in a position to calibrate instrumentation being used for the measurement of kerma and absorbed dose and their corresponding rates. This calibration is generally done with photons. In addition, since each neutron field is usually contaminated by photons produced in the source or by scatter in the surrounding media, neutron protection instrumentation has to be tested with respect to its intrinsic photon response. The laboratory will therefore need to possess equipment for photon calibration. This publication deals primarily with methods of applying radioactive neutron sources for calibration of instrumentation, and gives an indication of the space, manpower and facilities needed to fulfil the minimum requirements of a calibration laboratory for neutron work. It is intended to serve as a guide for centres about to start on neutron dosimetry standardization and calibration. 94 refs, 8 figs, 12 tabs

  19. THE INEXPENSIVE DEVICE FOR SEA LEVEL MEASUREMENTS

    Directory of Open Access Journals (Sweden)

    A. Annunziato

    2015-10-01

    Full Text Available A new mareograph device has been designed at the Joint Research Centre (JRC of the European Commission (EC in order improve the sea level network in use for the Tsunami Hazard monitoring in the Mediterranean Sea and in the North Atlantic area (NEAMTWS area of UNESCO. The instrument has the characteristic to be cheap and very effective but its reliability, duration and quality need to be determined and qualified. For this reason a number of experimental campaigns are being conducted, whose first results are presented here. In collaboration with the UNESCO/IOC (Intergovernmental Oceanographic Commission, responsible of the definition of the Tsunami Warning System of this geographical area, a set of 20 devices has been offered by JRC for a period of 1 year of testing of the devices; the surveys for the installation of the devices is under way and the installation should be completed by the end of 2015.

  20. Reversible (unitized) PEM fuel cell devices

    Energy Technology Data Exchange (ETDEWEB)

    Mitlitsky, F; Myers, B; Smith, W F; Weisberg, Molter, T M

    1999-06-01

    Regenerative fuel cells (RFCs) are enabling for many weight-critical portable applications, since the packaged specific energy (>400 Wh/kg) of properly designed lightweight RFC systems is several-fold higher than that of the lightest weight rechargeable batteries. RFC systems can be rapidly refueled (like primary fuel cells), or can be electrically recharged (like secondary batteries) if a refueling infrastructure is not conveniently available. Higher energy capacity systems with higher performance, reduced weight, and freedom from fueling infrastructure are the features that RFCs promise for portable applications. Reversible proton exchange membrane (PEM) fuel cells, also known as unitized regenerative fuel cells (URFCs), or reversible regenerative fuel cells, are RFC systems which use reversible PEM cells, where each cell is capable of operating both as a fuel cell and as an electrolyzer. URFCs further economize portable device weight, volume, and complexity by combining the functions of fuel cells and electrolyzers in the same hardware, generally without any system performance or efficiency reduction. URFCs are being made in many forms, some of which are already small enough to be portable. Lawrence Livermore National Laboratory (LLNL) has worked with industrial partners to design, develop, and demonstrate high performance and high cycle life URFC systems. LLNL is also working with industrial partners to develop breakthroughs in lightweight pressure vessels that are necessary for URFC systems to achieve the specific energy advantages over rechargeable batteries. Proton Energy Systems, Inc. (Proton) is concurrently developing and commercializing URFC systems (UNIGEN' product line), in addition to PEM electrolyzer systems (HOGEN' product line), and primary PEM fuel cell systems. LLNL is constructing demonstration URFC units in order to persuade potential sponsors, often in their own conference rooms, that advanced applications based on URFC s are

  1. Small Device For Short-Range Antenna Measurements Using Optics

    DEFF Research Database (Denmark)

    Yanakiev, Boyan Radkov; Nielsen, Jesper Ødum; Christensen, Morten;

    2011-01-01

    This paper gives a practical solution for implementing an antenna radiation pattern measurement device using optical fibers. It is suitable for anechoic chambers as well as short range channel sounding. The device is optimized for small size and provides a cheap and easy way to make optical antenna...... measurements using off-the-shelf components. Verification measurements are made to confirm the benefits....

  2. Development of a wireless blood pressure measuring device with smart mobile device.

    Science.gov (United States)

    İlhan, İlhan; Yıldız, İbrahim; Kayrak, Mehmet

    2016-03-01

    Today, smart mobile devices (telephones and tablets) are very commonly used due to their powerful hardware and useful features. According to an eMarketer report, in 2014 there were 1.76 billion smartphone users (excluding users of tablets) in the world; it is predicted that this number will rise by 15.9% to 2.04 billion in 2015. It is thought that these devices can be used successfully in biomedical applications. A wireless blood pressure measuring device used together with a smart mobile device was developed in this study. By means of an interface developed for smart mobile devices with Android and iOS operating systems, a smart mobile device was used both as an indicator and as a control device. The cuff communicating with this device through Bluetooth was designed to measure blood pressure via the arm. A digital filter was used on the cuff instead of the traditional analog signal processing and filtering circuit. The newly developed blood pressure measuring device was tested on 18 patients and 20 healthy individuals of different ages under a physician's supervision. When the test results were compared with the measurements made using a sphygmomanometer, it was shown that an average 93.52% accuracy in sick individuals and 94.53% accuracy in healthy individuals could be achieved with the new device. PMID:26626086

  3. Solar cell efficiency measurements

    International Nuclear Information System (INIS)

    Solar cells (and solar modules) have to be tested for their performance by means of sound reliable measurement procedures. The need for such measurements arises at various stages of research, of production, and of photovoltaic systems sizing and dimensioning. In fact, accurate measurements are necessary to the researcher, who studies new materials and new processes, to the manufacturer, who has to control his product and, finally, to the user, who needs sound measurements, in order to be in a position to make effective decisions about what kink of product will be needed and with what critical characteristics. In short, standard measurements that allow cells and modules to be characterized serve as a common language, allowing effective communication about products and requirements. 3 refs

  4. THE INEXPENSIVE DEVICE FOR SEA LEVEL MEASUREMENTS

    OpenAIRE

    A. Annunziato

    2015-01-01

    A new mareograph device has been designed at the Joint Research Centre (JRC) of the European Commission (EC) in order improve the sea level network in use for the Tsunami Hazard monitoring in the Mediterranean Sea and in the North Atlantic area (NEAMTWS area of UNESCO). The instrument has the characteristic to be cheap and very effective but its reliability, duration and quality need to be determined and qualified. For this reason a number of experimental campaigns are being conducted, whose ...

  5. 27 CFR 24.170 - Measuring devices and testing instruments.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Measuring devices and testing instruments. 24.170 Section 24.170 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS WINE Construction and Equipment § 24.170 Measuring devices and testing instruments....

  6. Device for measuring elastic modulus of superconducting coils (See 7903169)

    CERN Multimedia

    1979-01-01

    This device was made to measure elastic modulus of the Po dipole superconducting coils. More elaborated devices, but based on the same concept, were later used to measure the apparent elastic moduli of the LHC superconducting magnet coils. See also 7903169, 7901386.

  7. Device to measure elastic modulus of superconducting windings

    CERN Multimedia

    1979-01-01

    This device was made to measure elastic modulus of the Po dipole superconducting coils. More elaborated devices, but based on the same concept, were later used to measure the apparent elastic moduli of the LHC superconducting magnet coils. See also 7903547X, 7901386.

  8. Improved system measures output energy of pyrotechnic devices

    Science.gov (United States)

    Shortly, E. M.

    1966-01-01

    System for measuring the output energy of pyrotechnic devices discharges the reaction products into a test chamber. It measures the radiant heat output from a pinhole aperture as well as internal pressure changes on a common time base.

  9. A Strip Cell in Pyroelectric Devices.

    Science.gov (United States)

    Siao, An-Shen; Chao, Ching-Kong; Hsiao, Chun-Ching

    2016-01-01

    The pyroelectric effect affords the opportunity to convert temporal temperature fluctuations into usable electrical energy in order to develop abundantly available waste heat. A strip pyroelectric cell, used to enhance temperature variation rates by lateral temperature gradients and to reduce cell capacitance to further promote the induced voltage, is described as a means of improving pyroelectric energy transformation. A precision dicing saw was successfully applied in fabricating the pyroelectric cell with a strip form. The strip pyroelectric cell with a high-narrow cross section is able to greatly absorb thermal energy via the side walls of the strips, thereby inducing lateral temperature gradients and increasing temperature variation rates in a thicker pyroelectric cell. Both simulation and experimentation show that the strip pyroelectric cell improves the electrical outputs of pyroelectric cells and enhances the efficiency of pyroelectric harvesters. The strip-type pyroelectric cell has a larger temperature variation when compared to the trenched electrode and the original type, by about 1.9 and 2.4 times, respectively. The measured electrical output of the strip type demonstrates a conspicuous increase in stored energy as compared to the trenched electrode and the original type, by of about 15.6 and 19.8 times, respectively. PMID:26999134

  10. A Strip Cell in Pyroelectric Devices

    Directory of Open Access Journals (Sweden)

    An-Shen Siao

    2016-03-01

    Full Text Available The pyroelectric effect affords the opportunity to convert temporal temperature fluctuations into usable electrical energy in order to develop abundantly available waste heat. A strip pyroelectric cell, used to enhance temperature variation rates by lateral temperature gradients and to reduce cell capacitance to further promote the induced voltage, is described as a means of improving pyroelectric energy transformation. A precision dicing saw was successfully applied in fabricating the pyroelectric cell with a strip form. The strip pyroelectric cell with a high-narrow cross section is able to greatly absorb thermal energy via the side walls of the strips, thereby inducing lateral temperature gradients and increasing temperature variation rates in a thicker pyroelectric cell. Both simulation and experimentation show that the strip pyroelectric cell improves the electrical outputs of pyroelectric cells and enhances the efficiency of pyroelectric harvesters. The strip-type pyroelectric cell has a larger temperature variation when compared to the trenched electrode and the original type, by about 1.9 and 2.4 times, respectively. The measured electrical output of the strip type demonstrates a conspicuous increase in stored energy as compared to the trenched electrode and the original type, by of about 15.6 and 19.8 times, respectively.

  11. Measuring directional characteristics of in-ear recording devices

    DEFF Research Database (Denmark)

    Christensen, Flemming; Hoffmann, Pablo F.; Hammershøi, Dorte

    2013-01-01

    With the availability of small in-ear headphones and miniature microphones it is possible to construct combined in-ear devices for binaural recording and playback. When mounting a microphone on the outside of an insert earphone the microphone position deviates from ideal positions in the ear canal....... The pinna and thereby also the natural sound transmission are altered by the inserted device. This paper presents a methodology for accurately measuring the directional dependent transfer functions of such in-ear devices. Pilot measurements on a commercial available device are presented and...

  12. Correlation Measurements on Small Mobile Devices

    DEFF Research Database (Denmark)

    Yanakiev, Boyan Radkov; Nielsen, Jesper Ødum; Christensen, Morten;

    2012-01-01

    Here, analysis of the antenna correlation at the design stage is done, with focus on measurement techniques. Various theoretical definitions of correlations are used with the corresponding measured data required. The problems related to the coaxial measurement cables, when calculating correlation...... through the radiation patterns, are analyzed and an optical solution proposed. It is shown that using optical cable replacement, repeatable and accurate measurements of the envelope correlation coefficient can be made.......Here, analysis of the antenna correlation at the design stage is done, with focus on measurement techniques. Various theoretical definitions of correlations are used with the corresponding measured data required. The problems related to the coaxial measurement cables, when calculating correlation...

  13. Investigation of Electronic Devices for Strain Measurement

    Directory of Open Access Journals (Sweden)

    Ričardas Masiulionis

    2011-08-01

    Full Text Available Importance of strain measuring for safety of buildings is shown. The strain monitoring should be one of the buildings security systems. Often used balanced and non-balanced Wheatstone bridge strain measurement methods are analyzed. The Wheatstone bridge method with feedback is improved. A new method based on small resistance changes by the digital balancing currents is presented. Computer and experimental models of measurement are investigated. The received results confirm theoretical assumptions.Article in Lithuanian

  14. Test device for measuring permeability of a barrier material

    Science.gov (United States)

    Reese, Matthew; Dameron, Arrelaine; Kempe, Michael

    2014-03-04

    A test device for measuring permeability of a barrier material. An exemplary device comprises a test card having a thin-film conductor-pattern formed thereon and an edge seal which seals the test card to the barrier material. Another exemplary embodiment is an electrical calcium test device comprising: a test card an impermeable spacer, an edge seal which seals the test card to the spacer and an edge seal which seals the spacer to the barrier material.

  15. An inverted dielectrophoretic device for analysis of attached single cell mechanics.

    Science.gov (United States)

    Lownes Urbano, Rebecca; Morss Clyne, Alisa

    2016-02-01

    Dielectrophoresis (DEP), the force induced on a polarizable body by a non-uniform electric field, has been widely used to manipulate single cells in suspension and analyze their stiffness. However, most cell types do not naturally exist in suspension but instead require attachment to the tissue extracellular matrix in vivo. Cells alter their cytoskeletal structure when they attach to a substrate, which impacts cell stiffness. It is therefore critical to be able to measure mechanical properties of cells attached to a substrate. We present a novel inverted quadrupole dielectrophoretic device capable of measuring changes in the mechanics of single cells attached to a micropatterned polyacrylamide gel. The device is positioned over a cell of defined size, a directed DEP pushing force is applied, and cell centroid displacement is dynamically measured by optical microscopy. Using this device, single endothelial cells showed greater centroid displacement in response to applied DEP pushing force following actin cytoskeleton disruption by cytochalasin D. In addition, transformed mammary epithelial cell (MCF10A-NeuT) showed greater centroid displacement in response to applied DEP pushing force compared to untransformed cells (MCF10A). DEP device measurements were confirmed by showing that the cells with greater centroid displacement also had a lower elastic modulus by atomic force microscopy. The current study demonstrates that an inverted DEP device can determine changes in single attached cell mechanics on varied substrates. PMID:26738543

  16. Methods and Devices used to Measure Friction

    DEFF Research Database (Denmark)

    Jeswiet, Jack; Arentoft, Mogens; Henningsen, Poul

    2004-01-01

    . To gain a good understanding of the mechanisms at the interface and to be able to verify the friction and tribology models that exist, friction sensors are needed. Designing sensors to measure friction-stress in metal working has been pursued by many researchers. This paper surveys methods, which...... have been tried in the past and discusses some of the recent sensor designs, which can now be used to measure Friction in both production situations and for research purposes....

  17. Reactor core flow rate measuring device

    International Nuclear Information System (INIS)

    Purpose: To accurately measure the reactor core flow rate of coolants compulsorily circulated to the reactor core. Constitution: The discharge flow rate from internal pumps has been measured by disposing a flow nozzle, an orifice, etc. to the suction or discharge port of the internal pump and determining the pressure difference thereof or by the pumping stroke. Although such a method enables easy measurement, it involves problems in view of accuracy and maintenance. According to the present invention, a post-like member of a definite length is disposed to the opening of the reactor core shroud support leg just before an internal pump and the vortex frequency emitted from the member is measured to thereby determine the flow velocity and thus the flow rate. the vortex frequency is in proportion with the flow velocity, not depending on the composition, density, temperature, pressure of fluid. The vortex frequency is measured by a piezoelectric sensor or a strain gage. Accordingly, it is possible to accurately measure the discharge flow rate of individual internal pumps to thereby easily control the reactor core power. (K.M.)

  18. A Microfluidic Device for Spatiotemporal Delivery of Stimuli to Cells

    Directory of Open Access Journals (Sweden)

    Zubaidah Ningsih

    2015-03-01

    Full Text Available Living cells encounter many stimuli from the immediate environment. Receptors recognize these environmental cues and transduce signals to produce cell responses. The frequency of a signal is now emerging as an important factor determining cell responses. As a componentry system in understanding temporal stimulation, microfluidic devices allow the observation of cell behaviour under dynamic stimulation and controllable environment. In this paper we describe the design, construction and characterization of a microfluidic device suitable for cell stimulation studies.

  19. Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices

    OpenAIRE

    Halldórsson, Skarphédinn; Lucumi Moreno, Edinson; Gómez-Sjöberg, Rafael; Fleming, Ronan MT

    2015-01-01

    Culture of cells using various microfluidic devices is becoming more common within experimental cell biology. At the same time, a technological radiation of microfluidic cell culture device designs is currently in progress. Ultimately, the utility of microfluidic cell culture will be determined by its capacity to permit new insights into cellular function. Especially insights that would otherwise be difficult or impossible to obtain with macroscopic cell culture in traditional polystyrene dis...

  20. Practical, Microfabrication-Free Device for Single-Cell Isolation

    OpenAIRE

    Liang-I Lin; Shih-Hui Chao; Meldrum, Deirdre R.

    2009-01-01

    Microfabricated devices have great potential in cell-level studies, but are not easily accessible for the broad biology community. This paper introduces the Microscale Oil-Covered Cell Array (MOCCA) as a low-cost device for high throughput single-cell analysis that can be easily produced by researchers without microengineering knowledge. Instead of using microfabricated structures to capture cells, MOCCA isolates cells in discrete aqueous droplets that are separated by oil on patterned hydrop...

  1. Insertion device magnet measurements for the Advanced Light Source

    International Nuclear Information System (INIS)

    Allowable magnetic field errors for the 4.6 m long insertion devices for the Advanced Light Source (ALS) are extremely small and are driven by electron beam and radiation requirements. Detailed measurements and adjustments of each insertion device are performed to qualify them for installation in the ALS. To accomplish this, a high speed, precision magnetic measurement facility has been designed and built. Hall probe mapping equipment, capable of completing a 2500 sample, 6 m scan with precision axial position monitoring using a laser interferometer in under one minute, is used to obtain both local and integrated field information. A 5.5 m long, 1 cm wide coil is used to measure the field integral through an entire insertion device. This paper describes magnetic measurement equipment, and results of measurements on IDA, the first of the ALS insertion devices

  2. Video integrated measurement system. [Diagnostic display devices

    Energy Technology Data Exchange (ETDEWEB)

    Spector, B.; Eilbert, L.; Finando, S.; Fukuda, F.

    1982-06-01

    A Video Integrated Measurement (VIM) System is described which incorporates the use of various noninvasive diagnostic procedures (moire contourography, electromyography, posturometry, infrared thermography, etc.), used individually or in combination, for the evaluation of neuromusculoskeletal and other disorders and their management with biofeedback and other therapeutic procedures. The system provides for measuring individual diagnostic and therapeutic modes, or multiple modes by split screen superimposition, of real time (actual) images of the patient and idealized (ideal-normal) models on a video monitor, along with analog and digital data, graphics, color, and other transduced symbolic information. It is concluded that this system provides an innovative and efficient method by which the therapist and patient can interact in biofeedback training/learning processes and holds considerable promise for more effective measurement and treatment of a wide variety of physical and behavioral disorders.

  3. On-Demand Cell Internal Short Circuit Device

    Science.gov (United States)

    Darcy, Eric; Keyser, Matthew

    2014-01-01

    A device implantable in Li-ion cells that can generate a hard internal short circuit on-demand by exposing the cell to 60?C has been demonstrated to be valuable for expanding our understanding of cell responses. The device provides a negligible impact to cell performance and enables the instigation of the 4 general categories of cell internal shorts to determine relative severity and cell design susceptibility. Tests with a 18650 cell design indicates that the anode active material short to the aluminum cathode current collector tends to be more catastrophic than the 3 other types of internal shorts. Advanced safety features (such as shutdown separators) to prevent or mitigate the severity of cell internal shorts can be verified with this device. The hard short success rate achieved to date in 18650 cells is about 80%, which is sufficient for using these cells in battery assemblies for field-failure-relevant, cell-cell thermal runaway propagation verification tests

  4. Device for measuring the beta radiation of radioactive substances

    International Nuclear Information System (INIS)

    The switching device for measuring radiaoactive rare gases has two large area counting tubes operated with argon methane gas. Two anti-coincidence stages are provided in the evaluation electronics to suppress the background gamma radiation. (DG)

  5. Installation of an infrared measuring device in pressure release phenomena

    International Nuclear Information System (INIS)

    To analyze the saturated steam density and infrared measuring device was installed in a large scaled test facility. The possibility of accurate measuring of the density of two phase-two component flow and the ability to a rapid reaction on density oscillation are emphasized. In addition, the device allows an exact analysis of the density in two phase-two component flow with detailed information about the nature of condensation phenomena. (orig.)

  6. Quantum throughput: Quantifying quantum-communication devices with homodyne measurements

    International Nuclear Information System (INIS)

    Quantum communication relies on optical implementations of channels, memories, and repeaters. In the absence of perfect devices, a minimum requirement on real-world devices is that they preserve quantum correlations, meaning that they have some throughput of a quantum-mechanical nature. Previous work has verified throughput in optical devices while using minimal resources. We extend this approach to the quantitative regime. Our method is illustrated in a setting where the input consists of two coherent states while the output is measured by two homodyne measurement settings.

  7. Accuracy of portable devices in measuring peak cough flow

    International Nuclear Information System (INIS)

    Peak cough flow (PCF) measurements can be used as indicators of cough effectiveness. Portable peak flow meters and spirometers have been used to measure PCF, but little is known about their accuracy compared to pneumotachograph systems. The aim of this study was to compare the accuracy of four portable devices (Mini–Wright and Assess peak flow meters, SpiroUSB and Microlab spirometers) in measuring PCF with a calibrated laboratory based pneumotachograph system. Twenty healthy volunteers (mean (SD) age 45 (16) years) coughed through a pneumotachograph connected in series with each portable device in turn, and the differences in PCF readings were analysed. In addition, mechanically generated flow waves of constant peak flow were delivered through each device both independently and when connected in series with the pneumotachograph. Agreement between PCF readings obtained with the pneumotachograph and the portable devices was poor. Peak flow readings were on average lower by approximately 50 L min−1 when measured using the portable devices; 95% limits of agreement spanned approximately 150 L min−1. The findings highlight the potential for inaccuracy when using portable devices for the measurement of PCF. Depending on the measurement instrument used, absolute values of PCF reported in the literature may not be directly comparable. (paper)

  8. Measurement of Dose Distributions for Useful Utilization of BioBeam 8000 Gamma Irradiation Device

    International Nuclear Information System (INIS)

    Gamma irradiation device using Cs-137 have been widely utilized to the irradiation of cell, blood, and animal, and the dose measurement and education. Radiation irradiators for cell and blood irradiation used in numerous research institutions has demerits to perform the experiment of large volume objects like as 96 Multiwell Plate. Therefore, KIRAMS (Korea Institute of Radiological and Medical Sciences) introduced Gamma irradiation device having large volume capacity (BioBeam 8000, STS Steuerungstechnik and. Strahlenschutz GmbH, Braunschweig, Germany, Cs137, 3.35 Gy/min). In this study, dose the distribution of newly implemented BioBeam 8000 Gamma irradiation device was measured using glass dosimeter and Gafchromic EBT film dosimetry. In addition, an user guideline for useful utilization of the device based on measurement results are presented

  9. Scattermeter for measurement of solar cells

    Science.gov (United States)

    Nádaský, Pavel; Klus, Jakub; Vodák, Jiří; Šustek, Štěpán.; Ohlídal, Miloslav

    2015-09-01

    Scattermeter II is the second generation device designed and built at The Institute of Physical Engineering, Faculty of Mechanical Engineering, Brno University of Technology. This device has been designed for measuring the angular distribution of the intensity of electromagnetic radiation scattered from a surface of a solid. In this paper, the basic scheme of Scattermeter II and measuring principles with it are described. The results achieved in electromagnetic radiation scattering from surfaces of selected samples of single crystalline silicon wafers used in solar cells are also presented.

  10. 27 CFR 24.36 - Instruments and measuring devices.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Instruments and measuring devices. 24.36 Section 24.36 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS WINE Administrative and Miscellaneous Provisions Authorities § 24.36 Instruments and measuring...

  11. Urbmobi. A mobile measurement device for urban environmental monitoring

    NARCIS (Netherlands)

    Klok, E.J.; Mark, P.J. van der; Nieuwkoop, E.

    2014-01-01

    Within the Urbmobi research project, a novel mobile measurement device is developed for urban areas. It provides temporally and spatially distributed environmental data and fulfills the need for monitoring at various places without the costs for a large number of fixed measurement stations. Urbmobi

  12. 21 CFR 886.1430 - Ophthalmic contact lens radius measuring device.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ophthalmic contact lens radius measuring device... SERVICES (CONTINUED) MEDICAL DEVICES OPHTHALMIC DEVICES Diagnostic Devices § 886.1430 Ophthalmic contact lens radius measuring device. (a) Identification. An ophthalmic contact lens radius measuring device...

  13. Adhesion in flexible organic and hybrid organic/inorganic light emitting device and solar cells

    International Nuclear Information System (INIS)

    This paper presents the results of an experimental study of the adhesion between bi-material pairs that are relevant to organic light emitting devices, hybrid organic/inorganic light emitting devices, organic bulk heterojunction solar cells, and hybrid organic/inorganic solar cells on flexible substrates. Adhesion between the possible bi-material pairs is measured using force microscopy (AFM) techniques. These include: interfaces that are relevant to organic light emitting devices, hybrid organic/inorganic light emitting devices, bulk heterojunction solar cells, and hybrid combinations of titanium dioxide (TiO2) and poly(3-hexylthiophene). The results of AFM measurements are incorporated into the Derjaguin-Muller-Toporov model for the determination of adhesion energies. The implications of the results are then discussed for the design of robust organic and hybrid organic/inorganic electronic devices

  14. Photon absorption models in nanostructured semiconductor solar cells and devices

    CERN Document Server

    Luque, Antonio

    2015-01-01

    This book is intended to be used by materials and device physicists and also solar cells researchers. It models the performance characteristics of nanostructured solar cells and resolves the dynamics of transitions between several levels of these devices. An outstanding insight into the physical behaviour of these devices is provided, which complements experimental work. This therefore allows a better understanding of the results, enabling the development of new experiments and optimization of new devices. It is intended to be accessible to researchers, but also to provide engineering tools w

  15. Production, characterization and stability of organic solar cell devices

    Energy Technology Data Exchange (ETDEWEB)

    Gevorgyan, S.A.

    2010-01-15

    Despite the fact that the field of organic photovoltaics (OPVs) is in a rapid progress, organic solar cells continue taking backstage roll in the growing markets of various solar technologies. The main challenge of the field is to develop devices that would possess all the optimal properties required for efficient, stable and cheap solar cells, i.e. devices that can deliver high photoconversion efficiencies and long lifetimes and can be efficiently produced in large scales using roll-to-roll coating technologies. This dissertation is primarily devoted to the issues of photoconversion efficiency and device lifetimes. In particular, descriptions of some practical approaches for different device designs and processing of active layer for typical small scale OPV devices were presented. The emphasis was put on some optimizing techniques for processing of active layer that can significantly improve the device photoconversion efficiency. The techniques were further applied for manufacturing and characterization of solar cell devices based on various materials. In particular, a number of thermocleavable polymers were studied and devices based on such materials were produced and characterized. The applicability of such materials in photovoltaic devices was shown and further challenges were discussed. Another task of this work was to manufacture and study inverted device structures and compare their properties with normal structure based devices. Device based on both structure were successfully produced with same level of performance in terms of photoconversion efficiency, yet with totally different stability performance. As another task, metal oxides, such as MoO{sub 3} or V{sub 2}O{sub 5} were studied in solar cell devices as buffer layers instead of PEDOT:PSS. Although the device efficiencies obtained with metal oxides were inferior to PEDOT based device, it was shown that such materials can possibly improve the device efficiency if the processing of the layers is

  16. Measurements of Elastic Moduli of Silicone Gel Substrates with a Microfluidic Device

    OpenAIRE

    Gutierrez, Edgar; Groisman, Alex

    2011-01-01

    Thin layers of gels with mechanical properties mimicking animal tissues are widely used to study the rigidity sensing of adherent animal cells and to measure forces applied by cells to their substrate with traction force microscopy. The gels are usually based on polyacrylamide and their elastic modulus is measured with an atomic force microscope (AFM). Here we present a simple microfluidic device that generates high shear stresses in a laminar flow above a gel-coated substrate and apply the d...

  17. Methods of Measurement for Semiconductor Materials, Process Control, and Devices

    Science.gov (United States)

    Bullis, W. M. (Editor)

    1973-01-01

    The development of methods of measurement for semiconductor materials, process control, and devices is reported. Significant accomplishments include: (1) Completion of an initial identification of the more important problems in process control for integrated circuit fabrication and assembly; (2) preparations for making silicon bulk resistivity wafer standards available to the industry; and (3) establishment of the relationship between carrier mobility and impurity density in silicon. Work is continuing on measurement of resistivity of semiconductor crystals; characterization of generation-recombination-trapping centers, including gold, in silicon; evaluation of wire bonds and die attachment; study of scanning electron microscopy for wafer inspection and test; measurement of thermal properties of semiconductor devices; determination of S-parameters and delay time in junction devices; and characterization of noise and conversion loss of microwave detector diodes.

  18. Measurement Devices and the Psychophysiology of Consumer Behaviour

    DEFF Research Database (Denmark)

    Schwarzkopf, Stefan

    2015-01-01

    From the 1890s, psychophysiological measurement devices have played an important, but as yet under-theorized role in marketing and consumer research. Because of the recent advances made in neuromarketing, it is often assumed that these measurement devices ushered in a radically new understanding...... of neuromarketing back to the Fin-de-Siècle neurophysiological laboratory, I show that consumers' bodies and later on their brains became reconfigured as part of a dispositif made up of laboratory-based artefacts (measurement devices) and new ways of seeing the human brain and human behaviour. This dispositif...... of the type of subjectivity that underlies consumer behaviour. I argue instead that a posthuman view of the relationship between brain, mind and behaviour underpinned neurophysiological research into consumers from its very beginning in the late nineteenth century. By tracing the biopolitical potentialities...

  19. Measurement-device-independent entanglement-based quantum key distribution

    Science.gov (United States)

    Yang, Xiuqing; Wei, Kejin; Ma, Haiqiang; Sun, Shihai; Liu, Hongwei; Yin, Zhenqiang; Li, Zuohan; Lian, Shibin; Du, Yungang; Wu, Lingan

    2016-05-01

    We present a quantum key distribution protocol in a model in which the legitimate users gather statistics as in the measurement-device-independent entanglement witness to certify the sources and the measurement devices. We show that the task of measurement-device-independent quantum communication can be accomplished based on monogamy of entanglement, and it is fairly loss tolerate including source and detector flaws. We derive a tight bound for collective attacks on the Holevo information between the authorized parties and the eavesdropper. Then with this bound, the final secret key rate with the source flaws can be obtained. The results show that long-distance quantum cryptography over 144 km can be made secure using only standard threshold detectors.

  20. Intracavity Microfluidic Laser Device for Single Cell Analysis

    Science.gov (United States)

    Gourley, Paul

    2015-03-01

    An intracavity microfluidic laser device has been developed to study bioparticles ranging in size from 50 nm to 20 μm (virons to organelles to whole cells). The versatile device can be operated used in several modes including static or flowing fluids, with or without molecular labels, and microscopic imaging and/or spectroscopy. It enables advantageous new ways to perform analyses of bioparticles for applications including cell biology, detection of disease and pathogens, environmental monitoring, pharmaceuticals, agriculture, and food processing. This talk will briefly summarize the physics of the device including its laser optics, fluid dynamics, and intracavity light interaction with cells. The talk will then focus on results of a study of mitochondria in normal and cancer liver cells. The study examines the transformation of intracellular and isolated mitochondria from the normal to disease state. The results highlight the unique utility of the device to rapidly assess biophysical changes arising from altered biomolecular states of cells and organelles.

  1. Quantum dot optoelectronic devices: lasers, photodetectors and solar cells

    International Nuclear Information System (INIS)

    Nanometre-scale semiconductor devices have been envisioned as next-generation technologies with high integration and functionality. Quantum dots, or the so-called ‘artificial atoms’, exhibit unique properties due to their quantum confinement in all 3D. These unique properties have brought to light the great potential of quantum dots in optoelectronic applications. Numerous efforts worldwide have been devoted to these promising nanomaterials for next-generation optoelectronic devices, such as lasers, photodetectors, amplifiers, and solar cells, with the emphasis on improving performance and functionality. Through the development in optoelectronic devices based on quantum dots over the last two decades, quantum dot devices with exceptional performance surpassing previous devices are evidenced. This review describes recent developments in quantum dot optoelectronic devices over the last few years. The paper will highlight the major progress made in 1.3 μm quantum dot lasers, quantum dot infrared photodetectors, and quantum dot solar cells. (topical review)

  2. Micro- and nanostructured devices for cell studies

    OpenAIRE

    Beckwith, Kai Sandvold

    2015-01-01

    Cell culture is a fundamental and valuable tool for modern biomedical research. The purpose of this work has been to expand the possibilities and methods of cell culture through engineering of the cell culture substrate. A range of micro- and nanofabrication tools were used to structure new material systems and combinations that could be applied as cell interfaces. Several different material systems and applications were explored. Soft lithography was used to produce pattern...

  3. Single cell electroporation using microfluidic devices

    NARCIS (Netherlands)

    Le Gac, S.; Berg, van den A.; Lindstrom, S.; Andersson-Svahn, S.M.H.

    2012-01-01

    Electroporation is a powerful technique to increase the permeability of cell membranes and subsequently introduce foreign materials into cells. Pores are created in the cell membrane upon application of an electric fi eld (kV/cm). Most applications employ bulk electroporation, at the scale of 1 mL o

  4. Measurement of spin state using Stern-Gerlach devices

    International Nuclear Information System (INIS)

    The paper deals with the determination of the initial wave function of the measured physical system, i.e., finding the function module and phase. A version of the Stern-Gerlach device with a weak inhomogeneous magnetic field is suggested for the particle spin state determination. It is shown that this version realizes quantum measurement of a noncanonical kind. The comparison with the conventional Stern-Gerlach measurement is presented. We discuss the possibility of a reductionless measurement of the spin state when this state does not alter during its measurement. 12 refs

  5. Device and materials modeling in PEM fuel cells

    CERN Document Server

    Promislow, Keith

    2009-01-01

    Device and Materials Modeling in PEM Fuel Cells is a specialized text that compiles the mathematical details and results of both device and materials modeling in a single volume. Proton exchange membrane (PEM) fuel cells will likely have an impact on our way of life similar to the integrated circuit. The potential applications range from the micron scale to large scale industrial production. Successful integration of PEM fuel cells into the mass market will require new materials and a deeper understanding of the balance required to maintain various operational states. This book contains articles from scientists who contribute to fuel cell models from both the materials and device perspectives. Topics such as catalyst layer performance and operation, reactor dynamics, macroscopic transport, and analytical models are covered under device modeling. Materials modeling include subjects relating to the membrane and the catalyst such as proton conduction, atomistic structural modeling, quantum molecular dynamics, an...

  6. Device-Independent Quantum Key Distribution with Commuting Measurements

    CERN Document Server

    Hänggi, Esther

    2010-01-01

    We consider quantum key distribution in the device-independent scenario, i.e., where the legitimate parties do not know (or trust) the exact specification of their apparatus. We show how secure key distribution can be realized against the most general attacks by a quantum adversary under the condition that measurements on different subsystems by the honest parties commute.

  7. Multichannel measuring device of deformation for research materials of constructions

    OpenAIRE

    Druzhinin A.; Vuitsyk A.; Khoverko Yu.

    2008-01-01

    Possibility of Atmel ATMega microcontrollers use was shown for the interfacing of sensors devices with the modern computer systems. On the basis of Atmel ATMega16 microcontroller the multichannel system of treatment of information was developed for strain gauges, in which the amount of measuring channels is substantially increased.

  8. Multichannel measuring device of deformation for research materials of constructions

    Directory of Open Access Journals (Sweden)

    Druzhinin A.

    2008-06-01

    Full Text Available Possibility of Atmel ATMega microcontrollers use was shown for the interfacing of sensors devices with the modern computer systems. On the basis of Atmel ATMega16 microcontroller the multichannel system of treatment of information was developed for strain gauges, in which the amount of measuring channels is substantially increased.

  9. IN SITU FIELD PORTABLE FINE PARTICLE MEASURING DEVICE

    Science.gov (United States)

    The report describes the design, development, and testing of an in situ fine particle measuring device--the Fine Particle Stack Spectrometer System (FPSSS). It is a laser-fed optical system with detection by near-forward light scattering. Sample volume is established by a high-re...

  10. Mammography spectrum measurement using an x-ray diffraction device

    International Nuclear Information System (INIS)

    The use of a diffraction spectrometer developed by Deslattes for the determination of mammographic kV is extended to the measurement of accurate, relative x-ray spectra. Raw x-ray spectra (photon fluence versus energy) are determined by passing an x-ray beam through a bent quartz diffraction crystal, and the diffracted x-rays are detected by an x-ray intensifying screen coupled to a charge coupled device. Two nonlinear correction procedures, one operating on the energy axis and the other operating on the fluence axis, are described and performed on measured x-ray spectra. The corrected x-ray spectra are compared against tabulated x-ray spectra measured under nearly identical conditions. Results indicate that the current device is capable of producing accurate relative x-ray spectral measurements in the energy region from 12 keV to 40 keV, which represents most of the screen-film mammography energy range. Twelve keV is the low-energy cut-off, due to the design geometry of the device. The spectrometer was also used to determine the energy-dependent x-ray mass attenuation coefficients for aluminium, with excellent results in the 12-30 keV range. Additional utility of the device for accurately determining the attenuation characteristics of various normal and abnormal breast tissues and phantom substitutes is anticipated. (author)

  11. Development of an Ultrasonic Airflow Measurement Device for Ducted Air

    Directory of Open Access Journals (Sweden)

    Andrew B. Raine

    2015-05-01

    Full Text Available In this study, an in-duct ultrasonic airflow measurement device has been designed, developed and tested. The airflow measurement results for a small range of airflow velocities and temperatures show that the accuracy was better than 3.5% root mean square (RMS when it was tested within a round or square duct compared to the in-line Venturi tube airflow meter used for reference. This proof of concept device has provided evidence that with further development it could be a low-cost alternative to pressure differential devices such as the orifice plate airflow meter for monitoring energy efficiency performance and reliability of ventilation systems. The design uses a number of techniques and design choices to provide solutions to lower the implementation cost of the device compared to traditional airflow meters. The design choices that were found to work well are the single sided transducer arrangement for a “V” shaped reflective path and the use of square wave transmitter pulses ending with the necessary 180° phase changed pulse train to suppress transducer ringing. The device is also designed so that it does not have to rely on high-speed analogue to digital converters (ADC and intensive digital signal processing, so could be implemented using voltage comparators and low-cost microcontrollers.

  12. Experimental Measurements of Belt Gears in Newly Developed Device

    Directory of Open Access Journals (Sweden)

    Jozef Mascenik

    2016-05-01

    Full Text Available The paper deals with the alternative of determination of state of the belt gear. To realize themeasurements a newly developed device was designed for measurement and diagnostics of the belt gears. The main task is to detect the V-belt slip expressed by the coefficient of elastic creep and of specific slip with a measuring device. The measurements regarding can be performed if input revolutions of the electric motor and torque of the belt gear are constant whereas the tensioning force of the belt gear changes. It is also possible to perform the measurement if the input revolutions of the electric motor and the tensioning forces are constant and the torque changes.

  13. Measurements of fluid viscosity using a miniature ball drop device

    Science.gov (United States)

    Tang, Jay X.

    2016-05-01

    This paper describes measurement of fluid viscosity using a small ball drop device. It requires as little as 100 μl of fluid. Each measurement can be performed in seconds. The experiment is designed to yield reliable viscosity values by operating at properly chosen tilt angles and with calibration using well-characterized Newtonian fluids such as mixtures of glycerol and water. It also yields dynamical viscosity of non-Newtonian fluids at moderate shear rates. The device is easy to assemble and it allows for the measurement of viscosity even when the fluid samples are too small to measure using most commercial viscometers or rheometers. Therefore, the technique is particularly useful in characterizing biological fluids such as solutions of proteins, DNA, and polymers frequently used in biomaterial applications.

  14. Device for decisive measurements of large amounts of material

    International Nuclear Information System (INIS)

    During demolition of nuclear facilities, cleanup of radioactively contaminated areas or surveillance of food, large amounts of potentially radioactive materials have to be screened. A decisive measuring device was developed to measure large amounts of various materials with very low radioactivity. The device is sensitive to γ-radiation. The detectors are arranged on the outer surface of a channel with a cross section of 1,2 m2. Activities on complex surfaces and shielded activities can be measured. The minimal detectable activitiy for shielded activities (2 cm steel) is better than 300 Bq Co-60, everywhere within the measuring chamber. Up to mid 1989, more than 100 Mg of various materials have been screened for unrestricted release. (orig./HP)

  15. Device for absorption measurement of X-rays

    International Nuclear Information System (INIS)

    The device makes it possible to calculate the absorption of X-rays by the patient's head in the radiated layer by a matrix, using a computer. The intensity of radiation of two measuring units is used for this, one of which is at the entrance point of radiation in front of the head and the other one measures the radiation weakened by absorption by the head. (DG)

  16. New measuring and on water coaching device for rowing

    OpenAIRE

    Mattes, Klaus; Schaffert, Nina

    2010-01-01

    This article presents a new measuring and on water coaching device for rowing called “Accrow” which measures the boat acceleration with an acceleration sensor (50 Hz) and boat velocity with GPS (4 Hz). The data were analysed with the special software “Regatta”, based on scientific criteria and broad knowledge in biomechanical analysis of rowing training and races. In particular, “Regatta” performs three special analysis routines including every stroke: the boat motion for on-water training or...

  17. The optimization of measurement device independent quantum key distribution

    Science.gov (United States)

    Gao, Feng; Ma, Hai-Qiang; Jiao, Rong-Zhen

    2016-04-01

    Measurement device independent quantum key distribution (MDI-QKD) is a promising method for realistic quantum communication which could remove all the side-channel attacks from the imperfections of the devices. Here in this study, we theoretically analyzed the performance of the MDI-QKD system. The asymptotic case rate with the increment of the transmission distance at different polarization misalignment, background count rate and intensity is calculated respectively. The result may provide important parameters for practical application of quantum communications.

  18. Device for continuous measurement of straw briquette expansion

    Directory of Open Access Journals (Sweden)

    Molenda M.

    1999-03-01

    Full Text Available A device was developed for the continuous monitoring of the expansion of straw or hay briquettes after removal from the die. The instrument was tested within a trial of briquetting of various straws submitted for mechanical and chemical pre-treatments. The deve-loped device proved to be easy to use, while allowing measurement sensitivity better than 0.5 mm over a long period of time. It was possible to record even slight briquette expansion and to determine different trends of expansion for wheat and rice straw and for straws that had undergone different treatment.

  19. Device for continuous measurement of straw briquette expansion

    OpenAIRE

    Molenda M.; Ferrero A.

    1999-01-01

    A device was developed for the continuous monitoring of the expansion of straw or hay briquettes after removal from the die. The instrument was tested within a trial of briquetting of various straws submitted for mechanical and chemical pre-treatments. The deve-loped device proved to be easy to use, while allowing measurement sensitivity better than 0.5 mm over a long period of time. It was possible to record even slight briquette expansion and to determine different trends of expansion for w...

  20. A new 3D levitation force measuring device for REBCO bulk superconductors

    Energy Technology Data Exchange (ETDEWEB)

    Chen, S.L. [School of Physics, Shaanxi Normal University, Xi’an 710062 (China); Yang, W.M., E-mail: yangwm@snnu.edu.cn [School of Physics, Shaanxi Normal University, Xi’an 710062 (China); Li, J.W.; Yuan, X.C. [School of Physics, Shaanxi Normal University, Xi’an 710062 (China); Ma, J. [School of Physics, Shaanxi Normal University, Xi’an 710062 (China); Department of Physics, Qinghai Normal University, Xining 810008 (China); Wang, M. [School of Physics, Shaanxi Normal University, Xi’an 710062 (China)

    2014-01-15

    Highlights: •A new 3D levitation force measuring device has been designed and constructed. •It can measure the 3D real-time interaction force simultaneously and directly. •Performance, accuracy and effectiveness has been demonstrate by tests. -- Abstract: A new 3D levitation force measuring device for ReBa{sub 2}Cu{sub 3}O{sub 7−x} (REBCO) bulk superconductors has been designed and constructed. Three pull pressure load cells are orthogonally set on a fixing bracket to test the interaction force between a bulk superconductor and a magnet in three dimensions. To realize the simple, rapid and accurate measurement of the levitation force, a non-magnetic hollow cylinder flange, three pull pressure load cells, a piece of iron plate, a NbFeB permanent magnet (PM) and some steel balls are elaborately constructed with the fixing bracket, thus the magnet or REBCO bulk superconductor can be well and rigidly connected with the load cells, and the mutual interference from the three pull pressure load cells can be effectively avoided during the levitation force measuring processes. This device can be used to measure the interaction (or levitation) force between a superconductor and a magnet, that between a magnet and a magnet, or the magnetic force among magnetic materials in three dimensions.

  1. Organic solar cells fundamentals, devices, and upscaling

    CERN Document Server

    Rand, Barry P

    2014-01-01

    Solution-Processed DonorsB. Burkhart, B. C. ThompsonSmall-Molecule and Vapor-Deposited Organic Photovoltaics R. R. Lunt, R. J. HolmesAcceptor Materials for Solution-Processed Solar Cells Y. HeInterfacial Layers R. Po, C. Carbonera, A. BernardiElectrodes in Organic Photovoltaic Cells S. Yoo, J.-Y. Lee, H. Kim, J. LeeTandem and Multi-Junction Organic Solar Cells J. Gilot, R. A. J. JanssenBulk Heterojunction Morphology Control and Characterization T. Wang, D. G. LidzeyOptical Modeling and Light Management

  2. Resource-Efficient Measurement-Device-Independent Entanglement Witness

    Science.gov (United States)

    Verbanis, E.; Martin, A.; Rosset, D.; Lim, C. C. W.; Thew, R. T.; Zbinden, H.

    2016-05-01

    Imperfections in experimental measurement schemes can lead to falsely identifying, or over estimating, entanglement in a quantum system. A recent solution to this is to define schemes that are robust to measurement imperfections—measurement-device-independent entanglement witness (MDI-EW). This approach can be adapted to witness all entangled qubit states for a wide range of physical systems and does not depend on detection efficiencies or classical communication between devices. Here we extend the theory to remove the necessity of prior knowledge about the two-qubit states to be witnessed. Moreover, we tested this model via a novel experimental implementation for MDI-EW that significantly reduces the experimental complexity. By applying it to a bipartite Werner state, we demonstrate the robustness of this approach against noise by witnessing entanglement down to an entangled state fraction close to 0.4.

  3. Effective ultraviolet irradiance measurements from artificial tanning devices in Greece.

    Science.gov (United States)

    Petri, Aspasia; Karabetsos, Efthymios

    2015-12-01

    Artificial tanning remains very popular worldwide, despite the International Agency for Research on Cancer classification of ultraviolet (UV) radiation from sunbeds as 'carcinogenic to humans'. Greek Atomic Energy Commission has initiated a surveillance action of the artificial tanning devices in Greece in order to record the effective irradiance levels from the sunbeds and to inform and synchronise the domestic artificial tanning business sector with the requirements of the European Standard EN 60335-2-27:2010. In this direction, in situ measurements of UV emissions from sunbeds in solaria businesses all over Greece were performed from October 2013 until July 2014, with a radiometer and a portable single-monochromator spectrophotometer. Analysis of the measurements' results revealed that effective irradiance in ∼60 % of the measured sunbeds exceeded the 0.3 W m(-2) limit value set by EN 60335-2-27:2010 and only 20 % of the devices could be categorised as UV type 3. PMID:25468991

  4. Advanced Measurement Devices for the Microgravity Electromagnetic Levitation Facility EML

    Science.gov (United States)

    Brillo, Jurgen; Fritze, Holger; Lohofer, Georg; Schulz, Michal; Stenzel, Christian

    2012-01-01

    This paper reports on two advanced measurement devices for the microgravity electromagnetic levitation facility (EML), which is currently under construction for the use onboard the "International Space Station (ISS)": the "Sample Coupling Electronics (SCE)" and the "Oxygen Sensing and Control Unit (OSC)". The SCE measures by a contactless, inductive method the electrical resistivity and the diameter of a spherical levitated metallic droplet by evaluating the voltage and electrical current applied to the levitation coil. The necessity of the OSC comes from the insight that properties like surface tension or, eventually, viscosity cannot seriously be determined by the oscillating drop method in the EML facility without knowing the conditions of the surrounding atmosphere. In the following both measurement devices are explained and laboratory test results are presented.

  5. Real-time precision measuring device of tree diameter growth

    Science.gov (United States)

    Guo, Mingming; Chen, Aijun; Li, Dongsheng; Liu, Nan; Yao, Jingyuan

    2016-01-01

    DBH(diameter at breast height) is an important factor to reflect of the quality of plant growth, also an important parameter indispensable in forest resources inventory and forest carbon sink, the accurate measurement of DBH or not is directly related to the research of forest resources inventory and forest carbon sink. In this paper, the principle and the mathematical model of DBH measurement device were introduced, the fixture measuring device and the hardware circuit for this tree diameter were designed, the measurement software programs were compiled, and the precision measuring device of tree diameter growth was developed. Some experiments with Australia fir were conducted. Based on experiment data, the correlations among the DBH variation of Australian fir, the environment temperature, air humility and PAR(photosynthetically active radiation) were obtained. The effects of environmental parameters (environment temperature, air humility and PAR) on tree diameter were analyzed. Experimental results show that there is a positive correlation between DBH variation of Australian fir and environment temperature, a negative correlation between DBH variation of Australian fir and air humility , so is PAR.

  6. Radiation detection and measurement concepts, methods and devices

    CERN Document Server

    McGregor, Douglas

    2017-01-01

    This text on radiation detection and measurement is a response to numerous requests expressed by students at various universities, in which the most popularly used books do not provide adequate background material, nor explain matters in understandable terms. This work provides a modern overview of radiation detection devices and radiation measurement methods. The topics selected in the book have been selected on the basis of the author’s many years of experience designing radiation detectors and teaching radiation detection and measurement in a classroom environment.

  7. Device for measuring charge density distribution in charged particle beams

    International Nuclear Information System (INIS)

    A device to measure charge density distribution in charged particle beams has been described. The device contains a set of hollow interinsulated current-receiving electrodes, recording system, and cooling system. The invention is aimed at the increase of admissible capacity of the beams measured at the expense of cooling efficiency increase. The aim is achieved by the fact, that in the device a dynamic evaporating-condensational cooling of electrodes is realized by means of cooling agent supply in perpendicular to their planes through the tubes introduced inside special cups. Spreading in radial direction over electrode surface the cooling agent gradually and intensively washes the side surface of the cup, after that, it enters the cooling cavity in the form of vapour-liquid mixture. In the cavity the cooling agent, supplied using dispensina and receiving collectors in which vapoUr is condensed, circulates. In the device suggested the surface of electrode cooling is decreased significantly at the expense of side surface of the cups which receives the electrode heat

  8. Quantitative Study of Cell Invasion Process under Extracellular Stimulation of Cytokine in a Microfluidic Device

    Science.gov (United States)

    Lei, Kin Fong; Tseng, Hsueh-Peng; Lee, Chia-Yi; Tsang, Ngan-Ming

    2016-05-01

    Cell invasion is the first step of cancer metastasis that is the primary cause of death for cancer patients and defined as cell movement through extracellular matrix (ECM). Investigation of the correlation between cell invasive and extracellular stimulation is critical for the inhabitation of metastatic dissemination. Conventional cell invasion assay is based on Boyden chamber assay, which has a number of limitations. In this work, a microfluidic device incorporating with impedance measurement technique was developed for quantitative investigation of cell invasion process. The device consisted of 2 reservoirs connecting with a microchannel filled with hydrogel. Malignant cells invaded along the microchannel and impedance measurement was concurrently conducted by measuring across electrodes located at the bottom of the microchannel. Therefore, cell invasion process could be monitored in real-time and non-invasive manner. Also, cell invasion rate was then calculated to study the correlation between cell invasion and extracellular stimulation, i.e., IL-6 cytokine. Results showed that cell invasion rate was directly proportional to the IL-6 concentration. The microfluidic device provides a reliable and convenient platform for cell-based assays to facilitate more quantitative assessments in cancer research.

  9. Fractional exhaled nitric oxide measurement with a handheld device.

    Science.gov (United States)

    Magori, Erhard; Hiltawsky, Karsten; Fleischer, Maximilian; Simon, Elfriede; Pohle, Roland; von Sicard, Oliver; Tawil, Angelika

    2011-06-01

    A sensing system for fractional exhaled nitric oxide (FeNO) measurement is presented, which is characterized by a compact setup and a cost potential to be made available for the patient at home. The sensing is based on the work function measurement of a phthalocyanine-type sensing material, which is shown to be sufficiently sensitive for NO(2) in the ppb range. The transducer used to measure the work function is a field effect transistor with a suspended gate electrode. Selectivity is given with respect to other breath components including typically metabolic by-products. The measurement system includes breath treatments in a simple setup, which essentially are dehumidification and a quantitative conversion of NO to NO(2) with a conversion rate of approx. 95%, using a disposable oxidation catalyst. The accomplishment of the correct exhalation maneuver and feeding of the suited portion of exhaled air to the sensor is provided by breath sampling means. The sensor is not gas consuming. This allows us to fill the measurement chamber once, instead of establishing a gas flow for the measurement. This feature simplifies the device architecture. In this paper, we report on sensor characteristics, system architecture and measurement with artificial breath-gas as well as with human breath with the device. PMID:21646688

  10. The insertion device magnetic measurement facility: Prototype and operational procedures

    International Nuclear Information System (INIS)

    This report is a description of the current status of the magnetic measurement facility and is a basic instructional manual for the operation of the facility and its components. Please refer to the appendices for more detailed information about specific components and procedures. The purpose of the magnetic measurement facility is to take accurate measurements of the magnetic field in the gay of the IDs in order to determine the effect of the ID on the stored particle beam and the emitted radiation. The facility will also play an important role when evaluating new ideas, novel devices, and inhouse prototypes as part of the ongoing research and development program at the APS. The measurements will be performed with both moving search coils and moving Hall probes. The IDs will be evaluated by computer modeling of the emitted radiation for any given (measured) magnetic field map. The quality of the magnetic field will be described in terms of integrated multipoles for the effect on Storage Ring performance and in terms of the derived trajectories for the emitted radiation. Before being installed on the Storage Ring, every device will be measured and characterized to assure that it is compatible with Storage Ring requirements and radiation specifications. The accuracy that the APS needs to achieve for magnetic measurements will be based on these specifications

  11. Surface photovoltage measurements and finite element modeling of SAW devices.

    Energy Technology Data Exchange (ETDEWEB)

    Donnelly, Christine

    2012-03-01

    Over the course of a Summer 2011 internship with the MEMS department of Sandia National Laboratories, work was completed on two major projects. The first and main project of the summer involved taking surface photovoltage measurements for silicon samples, and using these measurements to determine surface recombination velocities and minority carrier diffusion lengths of the materials. The SPV method was used to fill gaps in the knowledge of material parameters that had not been determined successfully by other characterization methods. The second project involved creating a 2D finite element model of a surface acoustic wave device. A basic form of the model with the expected impedance response curve was completed, and the model is ready to be further developed for analysis of MEMS photonic resonator devices.

  12. In service parameters measurement device for nuclear reactor core

    International Nuclear Information System (INIS)

    The device has an instrument tube which can move inside the guide tube joining the reactor vessel at an instrumentation room by passing through a sealing nozzle. This nozzle forms a sealed chamber. The instrumentation tube contains peripheral measuring probes each of them in a sealed feed through for sliding the cable and its corresponding probe. Sealed feed throughs are also mounted on the exit wall for sliding the cable and probe out of the chamber

  13. Optical Measurement Techniques for Optical Fiber and Waveguide Devices

    Institute of Scientific and Technical Information of China (English)

    D.Y.; Kim; Y.; Park; N.H.; Seong; Y.C.Youk; J.Y.; Lee; S.; Moon; I.H.; Shin; H.S.; Ryu

    2003-01-01

    We describe three major optical characterization methods for fiber and fiber devices. A simple servo controlled scanning fiber-optic confocal microscope is proposed for determining the refractive index profile of an optical fiber. To measure the chromatic dispersion of a short length fiber a Mach-Zehnder fiber interferometer with a novel interferometric distance meter is introduced. At the end, a tomographic method is demonstrated for determining the 2-D stress profile of a fiber.

  14. A Device for Measurement of Capillary Refilling Time

    OpenAIRE

    Shamsudin, Nebil

    2012-01-01

    The main objective of this project is to design, construct and validate a portable prototype of a device that is capable of performing a test to accurately measure Capillary Refilling Time (CRT), and to analyze the results with defined parameters; force, area, pressure (compression) and time. This prototype is dedicated to study and evaluate CRT readouts for different pressure values, collected from healthy subjects.The presented prototype of this study is capable of producing skin compressin...

  15. Device for continuous tare measurement at belt weighers

    International Nuclear Information System (INIS)

    The described device can be used for belt weighers connected with a computing unit. Its development has been aimed at measuring the weight of the belt without standstill. This could be achieved by arranging radiation sources and detectors over the whole width of the belt and transforming the radiation attenuation into weight equivalents with the aid of an evaluation unit connected to the computing unit

  16. Cell compressibility studies utilizing noncontact hydrostatic pressure measurements on single living cells in a microchamber

    Science.gov (United States)

    Lin, L. A. G.; Liu, A. Q.; Yu, Y. F.; Zhang, C.; Lim, C. S.; Ng, S. H.; Yap, P. H.; Gao, H. J.

    2008-06-01

    A micro-optical-fluidic system (MOFS), which integrates a force generating device and an optical detector, is designed to measure the bulk modulus of a single living cell in real time under a controlled hydrostatic pressure. In this design, the accuracy of the bulk modulus measurement is improved because neither the force generating device nor the optical detector needs to be in contact with the cells. The MOFS device has been used to investigate the mechanotransduction of THP-1 human acute monocytic leukemia cells and the effects of the toxin lipopolysaccharide and colchicine on various properties of these cells.

  17. Microelectrical characterizations of junctions in solar cell devices by scanning Kelvin probe force microscopy

    International Nuclear Information System (INIS)

    Scanning Kelvin probe force microscopy was applied to the microelectrical characterizations of junctions in solar cell devices. Surface Fermi-level pinning effects on the surface potential measurement were avoided by applying a bias voltage (Vb) to the device and taking the Vb-induced potential and electric field changes. Two characterizations are presented: the first is a direct measurement of Bi-induced junction shift in GaInNAs(Bi) cells; the second is a junction-uniformity measurement in a-Si:H devices. In the first characterization, using Bi as a surfactant during the molecular beam epitaxy growth of GaInNAs(Bi) makes the epitaxial layer smoother. However, the electrical potential measurement exhibits a clear Bi-induced junction shift to the back side of the absorber layer, which results in significant device degradation. In the second characterization, the potential measurement reveals highly non-uniform electric field distributions across the n-i-p junction of a-Si:H devices; the electric field concentrates much more at both n/i and i/p interfaces than in the middle of the i-layer. This non-uniform electric field is due possibly to high defect concentrations at the interfaces. The potential measurements further showed a significant improvement in the electric field uniformity by depositing buffer layers at the interfaces, and this indeed improved the device performance.

  18. Mammalian cell retention devices for stirred perfusion bioreactors

    OpenAIRE

    Woodside, Steven M.; Bowen, Bruce D.; Piret, James M.

    1998-01-01

    Within the spectrum of current applications for cell culture technologies, efficient large-scale mammalian cell production processes are typically carried out in stirred fed-batch or perfusion bioreactors. The specific aspects of each individual process that can be considered when determining the method of choice are presented. A major challenge for perfusion reactor design and operation is the reliability of the cell retention device. Current retention systems include cross-flow membrane fil...

  19. Effect of bottom cell properties on micromorph tandem device performance

    OpenAIRE

    Delli Veneri, Paola; Mercaldo, Lucia Vittoria; PRIVATO Carlo

    2009-01-01

    Abstract Micromorph tandem solar cells represent an elegant way of overcoming the efficiency limits of single-junction solar cells and reducing the light-induced degradation of amorphous silicon films. Micromorph devices have been realized on Asahi U-type TCO-covered glass substrates by very high frequency plasma enhanced chemical vapour deposition (VHF-PECVD) at 100 MHz at low substrate temperature (150 ?C). For the bottom cell different growth regimes have been explored by changi...

  20. Cell-Based Biosensors: Electrical Sensing in Microfluidic Devices

    OpenAIRE

    Noemi Rozlosnik; Katrine Kiilerich-Pedersen

    2012-01-01

    Cell-based biosensors provide new horizons for medical diagnostics by adopting complex recognition elements such as mammalian cells in microfluidic devices that are simple, cost efficient and disposable. This combination renders possible a new range of applications in the fields of diagnostics and personalized medicine. The review looks at the most recent developments in cell-based biosensing microfluidic systems with electrical and electrochemical transduction, and relevance to medical diagn...

  1. Silicon device performance measurements to support temperature range enhancement

    Science.gov (United States)

    Bromstead, James; Weir, Bennett; Nelms, R. Mark; Johnson, R. Wayne; Askew, Ray

    1994-01-01

    Silicon based power devices can be used at 200 C. The device measurements made during this program show a predictable shift in device parameters with increasing temperature. No catastrophic or abrupt changes occurred in the parameters over the temperature range. As expected, the most dramatic change was the increase in leakage currents with increasing temperature. At 200 C the leakage current was in the milliAmp range but was still several orders of magnitude lower than the on-state current capabilities of the devices under test. This increase must be considered in the design of circuits using power transistors at elevated temperature. Three circuit topologies have been prototyped using MOSFET's and IGBT's. The circuits were designed using zero current or zero voltage switching techniques to eliminate or minimize hard switching of the power transistors. These circuits have functioned properly over the temperature range. One thousand hour life data have been collected for two power supplies with no failures and no significant change in operating efficiency. While additional reliability testing should be conducted, the feasibility of designing soft switched circuits for operation at 200 C has been successfully demonstrated.

  2. Improved Radiometric Calibrations and Measurements for Evaluating Photovoltaic Devices; TOPICAL

    International Nuclear Information System (INIS)

    The Photovoltaic Radiometric Measurements Task has improved broadband and spectral measurement capabilities at NREL. These improved NREL's capabilities affect the Photovoltaic Module and Array Performance and Reliability and Photovoltaic Measurements and Characterization Projects. Recent improvements (during 2000) in broadband radiometer calibrations result in the removal of bias errors on the order of 20 watts per square meter (W/m(sup 2)) in the measurement of global-hemispherical solar radiation. The improvements described are partially due to technical interactions by members of the Measurements and Instrumentation Team with the U.S. Department of Energy Atmospheric Radiation Measurement Program (ARM), National Aeronautics and Space Administration (NASA) Earth Observing System (EOS) Validation Program, World Meteorological Organization (WMO) Baseline Surface Measurement Network (BSRN), and National Oceanic and Atmospheric Administration (NOAA) Solar Radiation Research Branch (SRRB). New equipment has been purchased and techniques have been developed to characterize pulsed solar simulator spectral distributions. New equipment has been purchased and will be installed in the redesigned Solar Radiation Research Laboratory (SRRL) Baseline Measurement System (BMS). Expanded measurement capability, including sky radiance mapping, extensive ultraviolet and infrared radiation measurements, and routine spectral sampling will provide a unique complement of data for investigating PV device, module, and system design and performance, model development and validation, and for evaluating new measurement systems

  3. Device and method for measuring radioactive particles in oil

    International Nuclear Information System (INIS)

    A device for wear measurement of machine parts labelled with radioactive material is improved in such a way that a filter may be installed in the oil flow transporting the wear particles containing the radioisotopes to the place of measurement. It is then possible to study the wear behavior of intricate internal-combustion engines. For this purpose either the total oil flow or only part of it is conducted through the filter. Design details are exhaustively presented. (10 sub-claims). (UWI) 891 HP

  4. Indoor measurement of photovoltaic device characteristics at varying irradiance, temperature and spectrum for energy rating

    International Nuclear Information System (INIS)

    The first three-dimensional performance matrix for use in photovoltaic (PV) energy rating is reported utilizing a novel energy rating solar simulator based on LEDs. Device characteristics are measured indoors at varying irradiance (G), temperature (T) and spectrum (E). This opens the possibility for a more accurate measurement system for energy yield prediction of PV devices, especially for devices with high spectral dependence such as wide bandgap solar cells as they take into account spectral changes in the light. The main aspects of the LED-based solar simulator used are briefly described. A measurement method is developed and detailed in the paper, which takes into account the current imperfections in the achievable spectrum. Measurement results for a crystalline silicon solar cell are used to demonstrate the measurement approach. An uncertainty analysis of the measurement system is given, resulting in an overall absolute uncertainty of 4.3% (coverage factor k = 2) in maximum power measurements at 765 W m−2 irradiance with scope for further improvements

  5. Novel measure for the calibration of laser Doppler flowmetry devices

    Science.gov (United States)

    Dunaev, Andrey V.; Zherebtsov, Evgeny A.; Rogatkin, Dmitrii A.; Stewart, Neil A.; Sokolovski, Sergei G.; Rafailov, Edik U.

    2014-03-01

    The metrological basis for optical non-invasive diagnostic devices is an unresolved issue. A major challenge for laser Doppler flowmetry (LDF) is the need to compare the outputs from individual devices and various manufacturers to identify variations useful in clinical diagnostics. The most common methods for instrument calibration are simulants or phantoms composed of colloids of light-scattering particles which simulate the motion of red blood cells based on Brownian motion. However, such systems have limited accuracy or stability and cannot calibrate for the known rhythmic components of perfusion (0.0095-1.6 Hz). To solve this problem, we propose the design of a novel technique based on the simulation of moving particles using an electromechanical transducer, in which a precision piezoelectric actuator is used (e.g., P-602.8SL with maximum movement less than 1 mm). In this system, Doppler shift is generated in the layered structure of different solid materials with different optical light diffusing properties. This comprises a fixed, light transparent upper plane-parallel plate and an oscillating fluoroplastic (PTFE) disk. Preliminary studies on this experimental setup using the LDF-channel of a "LAKK-M" system demonstrated the detection of the linear portion (0-10 Hz with a maximum signal corresponding to Doppler shift of about 20 kHz) of the LDF-signal from the oscillating frequency of the moving layer. The results suggest the possibility of applying this technique for the calibration of LDF devices.

  6. Characterization of structural defects in GST based nano-PCM devices through resistance drift measurements

    Science.gov (United States)

    Cinar, Ibrahim; Cogulu, Egecan; Gokce, Aisha; Stipe, Barry; Katine, Jordan; Aktas, Gulen; Ozatay, Ozhan

    2015-03-01

    Phase change memory (PCM) is a promising nonvolatile data storage technology with its high signal to noise ratio and superior scalability. Resistance drift in amorphous phase of the phase change material poses a crucial reliability problem, especially in multiple-bit-per cell PCM devices. The resistance of the amorphous phase uncontrollably increases with time after a reset operation which alters the read/write conditions of the device. Structural relaxation (SR) through a defect annihilation process is considered to be the underlying physical mechanism for resistance drift. Here, we report on our measurements of the resistance drift in a phase change memory device with a single layer Ge2Sb2Te5 (GST) material not only in the amorphous state but also in the intermediate resistance state in devices with square top contact geometry which enables us to assess the reliability of multiple-bit per cell PCM memory devices. Through an analysis of electrical measurements as a function of time and temperature for increasing annealing times, we estimate a rate of change in trap density for both amorphous and mixed phases of the GST material after a switching operation. Our study allows engineering the phase change materials and optimizing programing conditions for future PCM applications. TUBITAK under Contract Number 113F385, Bogazici University Research Fund, 12B03M1, and European Union FP7 Marie Curie International Re-integration Grant PCM-256281.

  7. Nanostructured photovoltaic devices for next generation solar cell

    Science.gov (United States)

    Kim, Sung Jin

    2008-10-01

    As the search for alternative sources of energy other than petroleum continues to expand, solar energy conversion has already been identified as one of the most promising technologies. In the past few years there has been extensive research focused on the next generation solar cells that can exceed the Shockley-Queisser limit (a model that predicts the maximum achievable efficiency for a given material with a given bandgap). Moreover, nanoengineering approaches to enhance solar power conversion efficiency have started to receive considerable interest. Even in the most efficient commercially available solar devices utilizing crystalline silicon, a major portion of the absorbed ultraviolet photon energy is wasted as heat. Furthermore, this heat is detrimental to device reliability. Colloidal nanocrystal quantum dots (NQDs) offer the exciting prospect of simultaneously manipulating device and material structures and processes to enable more efficient solar energy conversion. Most importantly, these colloidal nanocrystal quantum dots are amenable to inexpensive fabrication techniques such as dip coating or spray coating of the constituent nanoscale materials onto various substrates. This dissertation focuses on the development of nanostructured photovoltaic devices, that exhibit multiple exciton generation, and that exploit the wide absorption spectra enabled by the quantum dots for next generation highly efficient, low cost, solar cells. Firstly, multiple exciton generation and subsequent electrical extraction from a thin film photoconductive device constructed from PbSe NQDs is demonstrated. As an extension of this work, this PbSe NQD photoconductor was used in a tandem structure with a polymer solar cell to demonstrate multiple carrier extraction the application of an external electric field. This structure exhibited improved device durability from UV irradiation due to the self-passivating effect provided by the PbSe layer. In order to achieve better exciton

  8. Magnetic field measurements in the electron cooling device for LEAR

    International Nuclear Information System (INIS)

    The field of the solenoid magnet to be used in the electron cooling device for LEAR has been investigated by careful field mapping. The magnetic field guiding the electron beam was measured in a volume with a cross-section of 6 x 6 cm2 around the electron beam axis, which is 4.5 m long and bent twice in toroidal sections. A Hall-plate field scanner designed for the mapping of dipole magnets was used to obtain separate field maps of all Cartesian field components in rectangular boxes covering the aforementioned measuring region. For merging these maps into a consistent overall field table, an evaluation procedure has been developed that includes careful survey and the correction of errors inherent in Hall-probe measurements. The measured data are presented in plots of field components and of field lines, and the magnetic field properties of the electron cooling device are discussed. A short description of the computer programs produced during this work is also given. (orig.)

  9. An unheated permeation device for calibrating atmospheric VOC measurements

    Directory of Open Access Journals (Sweden)

    J. Brito

    2011-10-01

    Full Text Available The development of an unpowered permeation device for continuous calibration of in-situ instruments measuring atmospheric volatile organic compounds (VOCs is described. Being lightweight and compact, and containing only negligible amounts of chemicals, the device is especially suited for field use such as on board aircraft. Its speciality is to maintain the permeation process in thermal equilibrium, so that the instantaneous permeation rate can be ascribed to a simple temperature measurement. This equilibrium state is maintained by a combination of three features: (i a thin PTFE membrane as permeation medium which guarantees short stabilization times, (ii a water bath as heat buffer, and (iii a vacuum-panel based insulation, in which features (ii and (iii minimize temperature drifts to ~30 mK h−1 per Kelvin temperature difference to the environment. The respective uncertainty of the permeation rate due to thermal non-equilibrium is kept below 1%. An extensive theory part details the major permeation processes of gases through porous polymers, being Fick's diffusion, Knudsen flow, and viscous flow. Both the measured stabilization time and the measured temperature dependence of the permeation rate independently indicate that the permeation can be described by a viscous flow model, where diffusion of the gas molecules in large pores (having a diameter of >0.05 μm dominates.

  10. An unheated permeation device for calibrating atmospheric VOC measurements

    Science.gov (United States)

    Brito, J.; Zahn, A.

    2011-10-01

    The development of an unpowered permeation device for continuous calibration of in-situ instruments measuring atmospheric volatile organic compounds (VOCs) is described. Being lightweight and compact, and containing only negligible amounts of chemicals, the device is especially suited for field use such as on board aircraft. Its speciality is to maintain the permeation process in thermal equilibrium, so that the instantaneous permeation rate can be ascribed to a simple temperature measurement. This equilibrium state is maintained by a combination of three features: (i) a thin PTFE membrane as permeation medium which guarantees short stabilization times, (ii) a water bath as heat buffer, and (iii) a vacuum-panel based insulation, in which features (ii) and (iii) minimize temperature drifts to ~30 mK h-1 per Kelvin temperature difference to the environment. The respective uncertainty of the permeation rate due to thermal non-equilibrium is kept below 1%. An extensive theory part details the major permeation processes of gases through porous polymers, being Fick's diffusion, Knudsen flow, and viscous flow. Both the measured stabilization time and the measured temperature dependence of the permeation rate independently indicate that the permeation can be described by a viscous flow model, where diffusion of the gas molecules in large pores (having a diameter of >0.05 μm) dominates.

  11. Dynamic monitoring of single cell lysis in an impedance-based microfluidic device.

    Science.gov (United States)

    Zhou, Ying; Basu, Srinjan; Laue, Ernest D; Seshia, Ashwin A

    2016-08-01

    A microfluidic device that is capable of trapping and sensing dynamic variations in the electrical properties of individual cells is demonstrated. The device is applied to the real-time recording of impedance measurements of mouse embryonic stem cells (mESCs) during the process of membrane lysis, with the resulting changes in the electrical properties of cells during this process being quantitatively tracked over time. It is observed that the impedance magnitude decreases dramatically after cell membrane lysis. A significant shift in the phase spectrum is also observed during the time course of this process. By fitting experimental data to physical models, the electrical parameters of cells can be extracted and parameter variations quantified during the process. In the cell lysis experiments, the equivalent conductivity of the cell membrane is found to increase significantly due to pore formation in the membrane during lysis. An increase in the specific capacitance of the membrane is also observed. On the other hand, the conductivity of the cytoplasm is observed to decrease, which may be explained the fact that excess water enters the cell through the gradual permeabilization of the membrane during lysis. Cells can be trapped in the device for periods up to several days, and their electrical response can be monitored by real-time impedance measurements in a label-free and non-invasive manner. Furthermore, due to the highly efficient single cell trapping capacity of the device, a number of cells can be trapped and held in separate wells for concurrent parallel experiments, allowing for the possibility of stepped parametric experiments and studying cell heterogeneity by combining measurements across the array. PMID:27299468

  12. Practical, microfabrication-free device for single-cell isolation.

    Directory of Open Access Journals (Sweden)

    Liang-I Lin

    Full Text Available Microfabricated devices have great potential in cell-level studies, but are not easily accessible for the broad biology community. This paper introduces the Microscale Oil-Covered Cell Array (MOCCA as a low-cost device for high throughput single-cell analysis that can be easily produced by researchers without microengineering knowledge. Instead of using microfabricated structures to capture cells, MOCCA isolates cells in discrete aqueous droplets that are separated by oil on patterned hydrophilic areas across a relatively more hydrophobic substrate. The number of randomly seeded Escherichia coli bacteria in each discrete droplet approaches single-cell levels. The cell distribution on MOCCA is well-fit with Poisson distribution. In this pioneer study, we created an array of 900-picoliter droplets. The total time needed to seed cells in approximately 3000 droplets was less than 10 minutes. Compared to traditional microfabrication techniques, MOCCA dramatically lowers the cost of microscale cell arrays, yet enhances the fabrication and operational efficiency for single-cell analysis.

  13. Flow measurements in a centrifugal diffusor test device

    Science.gov (United States)

    Vitting, T.

    1985-06-01

    This work sought to verify concepts used in the design of a large scale, low speed, radial cascade wind tunnel which was to be used to investigate flow phenomena in and the performance of vaned radial diffusors. A major contributor to centrifugal compressor efficiency is the performance of the vaned diffusor which closely follows the impeller of the compressor. The purpose of this diffusor is to efficiently convert most of the kinetic energy of the transonic flow entering the vane into pressure. The need for an experimental facility which could simulate adequately, at low cost and in a controlled way, the environment of the centrifugal compressor motivated the development of the Centrifugal Diffusor Test Device (CDTD). It was expected that the generation of a three dimensional flow would provide improved empirical data on annular cascade performance. This measurement program surveyed the axial and circumferential uniformity of the flow at the inlet of a transonic wedge-type blading mounted in the device. Evaluation of the results showed the flow uniformity to be unsatisfactory. Leakage and other small perturbations in the flow field in the swirl generator are believed to be amplified by the basic flow configuration of the device.

  14. PARduino: A Simple Device Measuring and Logging Photosynthetically Active Radiation

    Science.gov (United States)

    Barnard, H. R.; Findley, M. C.

    2013-12-01

    Photosynthetically Active Radiation (PAR, 400 to 700 nm) is one of the primary controls of forest carbon and water relations. In complex terrain, PAR has high spatial-variability. Given the high cost of commercial datalogging equipment, spatially-distributed measurements of PAR have been typically modeled using geographic coordinates and terrain indices. Here, we present a design for a low cost, field-deployable device for measuring and logging PAR built around an Arduino microcontroller (we named it PARduino). PARduino provides for widely distributed sensor arrays and tests the feasibility of using hobbyist-grade electronics for collecting scientific data. PARduino components include a LiCor quantum sensor, EME Systems signal converter/amplifier, and Sparkfun's Arduino Pro Mini microcontroller. Additional components include a real time clock, a microSD flash memory card, and a custom printed circuit board (PCB). We selected the components with an eye towards ease of assembly. Everything can be connected to the PCB using through-hole soldering techniques. Since the device will be deployed in remote research plots that lack easy access to line power, battery life was also a consideration in the design. Extended deployment is possible because PARduino's software keeps it in a low-power sleep mode until ready to make a measurement. PARduino will be open-source hardware for use and improvement by others.

  15. Effective ultraviolet irradiance measurements from artificial tanning devices in Greece

    International Nuclear Information System (INIS)

    Artificial tanning remains very popular worldwide, despite the International Agency for Research on Cancer classification of ultraviolet (UV) radiation from sun-beds as 'carcinogenic to humans'. Greek Atomic Energy Commission has initiated a surveillance action of the artificial tanning devices in Greece in order to record the effective irradiance levels from the sun-beds and to inform and synchronise the domestic artificial tanning business sector with the requirements of the European Standard EN 60335-2-27:2010. In this direction, in situ measurements of UV emissions from sun-beds in solaria businesses all over Greece were performed from October 2013 until July 2014, with a radiometer and a portable single-monochromator spectrophotometer. Analysis of the measurements' results revealed that effective irradiance in ∼60 % of the measured sun-beds exceeded the 0.3 W m-2 limit value set by EN 60335-2-27:2010 and only 20 % of the devices could be categorised as UV type 3. (authors)

  16. Development of microfluidic device for cell counting and lysis

    Czech Academy of Sciences Publication Activity Database

    Václavek, Tomáš; Křenková, Jana; Foret, František

    Veszprém : Hungarian Society for Separation Sciences, 2015. s. 140-140. ISBN 978-615-5270-18-5. [Balaton Symposium on High-Performance Separation Methods /10./. 02.09.2015-04.09.2015, Siófok] R&D Projects: GA ČR(CZ) GA14-06319S; GA ČR(CZ) GBP206/12/G014 Institutional support: RVO:68081715 Keywords : microfluidic device * cell counting * cell lysis Subject RIV: CB - Analytical Chemistry, Separation

  17. Continuous-variable measurement-device-independent multipartite quantum communication

    Science.gov (United States)

    Wu, Yadong; Zhou, Jian; Gong, Xinbao; Guo, Ying; Zhang, Zhi-Ming; He, Guangqiang

    2016-02-01

    A continuous-variable measurement-device-independent multiparty quantum communication protocol is investigated in this paper. Utilizing the distributed continuous-variable Greenberger-Horne-Zeilinger state, this protocol can implement both quantum cryptographic conference and quantum secret sharing. We analyze the security of the protocol against both the entangling cloner attack and the coherent attack. The entangling cloner attack is a practical individual attack, and the coherent attack is the optimal attack Eve can implement. Simulation results show that the coherent attack can greatly reduce the secret key rate. Different kinds of entangled attacks are compared and we finally discuss the optimal coherent attacks.

  18. Alternative schemes for measurement-device-independent quantum key distribution

    CERN Document Server

    Ma, Xiongfeng

    2012-01-01

    A practical scheme for measurement-device-independent quantum key distribution using phase and path/time encoding is presented. In addition to immunity to existing loopholes in detection systems, our setup employs simple encoding and decoding modules without relying on polarization maintenance or optical switches. Moreover, by handling, with a modified sifting technique, the dead time limitations in single-photon detectors, our scheme can be run with only two single-photon detectors. With a phase-post-selection technique, a decoy-state variant of our scheme is also proposed, whose secret key generation rate scales linearly with the channel transmittance.

  19. Advanced materials and processes for polymer solar cell devices

    DEFF Research Database (Denmark)

    Petersen, Martin Helgesen; Søndergaard, Roar; Krebs, Frederik C

    2010-01-01

    The rapidly expanding field of polymer and organic solar cells is reviewed in the context of materials, processes and devices that significantly deviate from the standard approach which involves rigid glass substrates, indium-tin-oxide electrodes, spincoated layers of conjugated polymer...

  20. Transport Mechanisms of Circulating Tumor Cells in Microfluidic Devices

    Science.gov (United States)

    Rangharajan, Kaushik; Conlisk, A. T.; Prakash, Shaurya

    2014-11-01

    Lab-on-a-chip (LoC) devices are becoming an essential tool for several emerging point-of-care healthcare needs and applications. Among the plethora of challenging problems in the personalized healthcare domain, early detection of cancer continues to be a challenge. For instance, identification of most tumors occurs by the time the tumor comprises approximately 1 billion cells, with poor prognosis for metastatic disease. The key obstacle in identifying and subsequent capture of circulating tumor cells (CTCs) is that the amount of CTCs in the blood stream is ~1 in 109 cells. The fundamental challenge in design and fabrication of microfluidic devices arises due to lack of information on suitable sorting needed for sample preparation before any labeling or capture scheme can be employed. Moreover, the ability to study these low concentration cells relies on knowledge of their physical and chemical properties, of which the physical properties are poorly understood. Also, nearly all existing microfluidic mixers were developed for aqueous electrolyte solutions to enhance mixing in traditional low Re flows. However, no systematic studies have developed design rules for particle mixing. Therefore, we present a numerical model to discuss design rules for microscale mixers and sorters for particle sorting for high efficiency antibody labeling of CTCs along with presenting a pathway for a device to capture CTCs without the need for labeling based on particle electrical properties. NSF Nanoscale Science and Engineering Center (NSEC) for the Affordable Nanoengineering of Polymeric Biomedical Devices EEC-0914790.

  1. Design of a Device for Sky Light Polarization Measurements

    Directory of Open Access Journals (Sweden)

    Yujie Wang

    2014-08-01

    Full Text Available ky polarization patterns can be used both as indicators of atmospheric turbidity and as a sun compass for navigation. The objective of this study is to improve the precision of sky light polarization measurements by optimal design of the device used. The central part of the system is composed of a Charge Coupled Device (CCD camera; a fish-eye lens and a linear polarizer. Algorithms for estimating parameters of the polarized light based on three images are derived and the optimal alignments of the polarizer are analyzed. The least-squares estimation is introduced for sky light polarization pattern measurement. The polarization patterns of sky light are obtained using the designed system and they follow almost the same patterns of the single-scattering Rayleigh model. Deviations of polarization angles between observation and the theory are analyzed. The largest deviations occur near the sun and anti-sun directions. Ninety percent of the deviations are less than 5° and 40% percent of them are less than 1°. The deviations decrease evidently as the degree of polarization increases. It also shows that the polarization pattern of the cloudy sky is almost identical as in the blue sky.

  2. High-rate measurement-device-independent quantum cryptography

    Science.gov (United States)

    Pirandola, Stefano; Ottaviani, Carlo; Spedalieri, Gaetana; Weedbrook, Christian; Braunstein, Samuel L.; Lloyd, Seth; Gehring, Tobias; Jacobsen, Christian S.; Andersen, Ulrik L.

    2015-06-01

    Quantum cryptography achieves a formidable task—the remote distribution of secret keys by exploiting the fundamental laws of physics. Quantum cryptography is now headed towards solving the practical problem of constructing scalable and secure quantum networks. A significant step in this direction has been the introduction of measurement-device independence, where the secret key between two parties is established by the measurement of an untrusted relay. Unfortunately, although qubit-implemented protocols can reach long distances, their key rates are typically very low, unsuitable for the demands of a metropolitan network. Here we show, theoretically and experimentally, that a solution can come from the use of continuous-variable systems. We design a coherent-state network protocol able to achieve remarkably high key rates at metropolitan distances, in fact three orders of magnitude higher than those currently achieved. Our protocol could be employed to build high-rate quantum networks where devices securely connect to nearby access points or proxy servers.

  3. A Device to Measure the Propulsive Power of Nematodes

    CERN Document Server

    Yuan, J; Gnatt, M; Raizen, D M; Bau, H H

    2011-01-01

    In the fluid dynamics video, we present a microfluidic device to measure the propulsive power of nematodes. The device consists of a tapered conduit filled with aqueous solution. The conduit is subjected to a DC electric field with the negative pole at the narrow end and to pressure-driven flow directed from the narrow end. The nematode is inserted at the conduit's wide end. Directed by the electric field (through electrotaxis), the nematode swims deliberately upstream toward the negative pole of the DC field. As the conduit narrows, the average fluid velocity and the drag force on the nematode increase. Eventually, the nematode arrives at an equilibrium position, at which its propulsive force balances the viscous drag force induced by the adverse flow. The equilibrium position of different animals, with similar body lengths, was measured as a function of the flow rate. The flow field around the nematode was obtained by direct numerical simulations with the experimentally imaged gait and the tapered geometry ...

  4. Measuring device for water quality at reactor bottom

    International Nuclear Information System (INIS)

    The present invention concerns measurement for water quality at the bottom of a reactor of a BWR type plant, in which reactor water is sampled and analyzed in a state approximate to conditions in a pressure vessel. Based on the result, hydrogen injection amount is controlled during hydrogen injection operation. Namely, a monitor for water quality is disposed to a sampling line in communication with the bottom of a pressure vessel. A water quality monitor is disposed to a drain sampling line in communication with the bottom of the pressure vessel. A corrosion potentiometer is disposed to the pressure sampling line or the drain sampling line. A dissolved oxygen measuring device is disposed to the pressure vessel sampling line or the drain sampling line. With such a constitution, the reactor water can be sampled and analyzed in a state approximate to the conditions in the pressure vessel. In addition, signals from the water quality monitor are inputted to a hydrogen injection amount control device. As a result, the amount of hydrogen injected to primary coolants can be controlled in a state approximate to the conditions in the pressure vessel. (I.S.)

  5. A combined travelling wave dielectrophoresis and impedance sensing device for sensing biological cell suspensions

    International Nuclear Information System (INIS)

    A suspended particle sensing technique called travelling wave dielectrophoresis impedance measurement (TWDIM) is presented which uses travelling wave dielectrophoresis to concentrate suspended particles in solution to a subset of electrodes through which impedance sensing is used to sense particle concentrations. A microfabricated TWDIM device and associated electronic systems are presented, as well as methods of operation and experimental results determining yeast cell concentrations

  6. Acoustic Devices for Particle and Cell Manipulation and Sensing

    Directory of Open Access Journals (Sweden)

    Yongqiang Qiu

    2014-08-01

    Full Text Available An emerging demand for the precise manipulation of cells and particles for applications in cell biology and analytical chemistry has driven rapid development of ultrasonic manipulation technology. Compared to the other manipulation technologies, such as magnetic tweezing, dielectrophoresis and optical tweezing, ultrasonic manipulation has shown potential in a variety of applications, with its advantages of versatile, inexpensive and easy integration into microfluidic systems, maintenance of cell viability, and generation of sufficient forces to handle particles, cells and their agglomerates. This article briefly reviews current practice and reports our development of various ultrasonic standing wave manipulation devices, including simple devices integrated with high frequency (>20 MHz ultrasonic transducers for the investigation of biological cells and complex ultrasonic transducer array systems to explore the feasibility of electronically controlled 2-D and 3-D manipulation. Piezoelectric and passive materials, fabrication techniques, characterization methods and possible applications are discussed. The behavior and performance of the devices have been investigated and predicted with computer simulations, and verified experimentally. Issues met during development are highlighted and discussed. To assist long term practical adoption, approaches to low-cost, wafer level batch-production and commercialization potential are also addressed.

  7. A review of impedance measurements of whole cells.

    Science.gov (United States)

    Xu, Youchun; Xie, Xinwu; Duan, Yong; Wang, Lei; Cheng, Zhen; Cheng, Jing

    2016-03-15

    Impedance measurement of live biological cells is widely accepted as a label free, non-invasive and quantitative analytical method to assess cell status. This method is easy-to-use and flexible for device design and fabrication. In this review, three typical techniques for impedance measurement, i.e., electric cell-substrate impedance sensing, Impedance flow cytometry and electric impedance spectroscopy, are reviewed from the aspects of theory, to electrode design and fabrication, and applications. Benefiting from the integration of microelectronic and microfluidic techniques, impedance sensing methods have expanded their applications to nearly all aspects of biology, including living cell counting and analysis, cell biology research, cancer research, drug screening, and food and environmental safety monitoring. The integration with other techniques, the fabrication of devices for certain biological assays, and the development of point-of-need diagnosis devices is predicted to be future trend for impedance sensing techniques. PMID:26513290

  8. Novel Hydrogen Purification Device Integrated with PEM Fuel Cells

    Energy Technology Data Exchange (ETDEWEB)

    Joseph Schwartz; Hankwon Lim; Raymond Drnevich

    2010-12-31

    A prototype device containing twelve membrane tubes was designed, built, and demonstrated. The device produced almost 300 scfh of purified hydrogen at 200 psig feed pressure. The extent of purification met the program target of selectively removing enough impurities to enable industrial-grade hydrogen to meet purity specifications for PEM fuel cells. An extrusion process was developed to produce substrate tubes. Membranes met several test objectives, including completing 20 thermal cycles, exceeding 250 hours of operating life, and demonstrating a flux of 965 scfh/ft2 at 200 psid and 400 C.

  9. Measurements of elastic moduli of silicone gel substrates with a microfluidic device.

    Directory of Open Access Journals (Sweden)

    Edgar Gutierrez

    Full Text Available Thin layers of gels with mechanical properties mimicking animal tissues are widely used to study the rigidity sensing of adherent animal cells and to measure forces applied by cells to their substrate with traction force microscopy. The gels are usually based on polyacrylamide and their elastic modulus is measured with an atomic force microscope (AFM. Here we present a simple microfluidic device that generates high shear stresses in a laminar flow above a gel-coated substrate and apply the device to gels with elastic moduli in a range from 0.4 to 300 kPa that are all prepared by mixing two components of a transparent commercial silicone Sylgard 184. The elastic modulus is measured by tracking beads on the gel surface under a wide-field fluorescence microscope without any other specialized equipment. The measurements have small and simple to estimate errors and their results are confirmed by conventional tensile tests. A master curve is obtained relating the mixing ratios of the two components of Sylgard 184 with the resulting elastic moduli of the gels. The rigidity of the silicone gels is less susceptible to effects from drying, swelling, and aging than polyacrylamide gels and can be easily coated with fluorescent tracer particles and with molecules promoting cellular adhesion. This work can lead to broader use of silicone gels in the cell biology laboratory and to improved repeatability and accuracy of cell traction force microscopy and rigidity sensing experiments.

  10. Measurements of elastic moduli of silicone gel substrates with a microfluidic device.

    Science.gov (United States)

    Gutierrez, Edgar; Groisman, Alex

    2011-01-01

    Thin layers of gels with mechanical properties mimicking animal tissues are widely used to study the rigidity sensing of adherent animal cells and to measure forces applied by cells to their substrate with traction force microscopy. The gels are usually based on polyacrylamide and their elastic modulus is measured with an atomic force microscope (AFM). Here we present a simple microfluidic device that generates high shear stresses in a laminar flow above a gel-coated substrate and apply the device to gels with elastic moduli in a range from 0.4 to 300 kPa that are all prepared by mixing two components of a transparent commercial silicone Sylgard 184. The elastic modulus is measured by tracking beads on the gel surface under a wide-field fluorescence microscope without any other specialized equipment. The measurements have small and simple to estimate errors and their results are confirmed by conventional tensile tests. A master curve is obtained relating the mixing ratios of the two components of Sylgard 184 with the resulting elastic moduli of the gels. The rigidity of the silicone gels is less susceptible to effects from drying, swelling, and aging than polyacrylamide gels and can be easily coated with fluorescent tracer particles and with molecules promoting cellular adhesion. This work can lead to broader use of silicone gels in the cell biology laboratory and to improved repeatability and accuracy of cell traction force microscopy and rigidity sensing experiments. PMID:21980487

  11. Testing limits to airflow perturbation device (APD measurements

    Directory of Open Access Journals (Sweden)

    Jamshidi Shaya

    2008-10-01

    Full Text Available Abstract Background The Airflow Perturbation Device (APD is a lightweight, portable device that can be used to measure total respiratory resistance as well as inhalation and exhalation resistances. There is a need to determine limits to the accuracy of APD measurements for different conditions likely to occur: leaks around the mouthpiece, use of an oronasal mask, and the addition of resistance in the respiratory system. Also, there is a need for resistance measurements in patients who are ventilated. Method Ten subjects between the ages of 18 and 35 were tested for each station in the experiment. The first station involved testing the effects of leaks of known sizes on APD measurements. The second station tested the use of an oronasal mask used in conjunction with the APD during nose and mouth breathing. The third station tested the effects of two different resistances added in series with the APD mouthpiece. The fourth station tested the usage of a flexible ventilator tube in conjunction with the APD. Results All leaks reduced APD resistance measurement values. Leaks represented by two 3.2 mm diameter tubes reduced measured resistance by about 10% (4.2 cmH2O·sec/L for control and 3.9 cm H2O·sec/L for the leak. This was not statistically significant. Larger leaks given by 4.8 and 6.4 mm tubes reduced measurements significantly (3.4 and 3.0 cm cmH2O·sec/L, respectively. Mouth resistance measured with a cardboard mouthpiece gave an APD measurement of 4.2 cm H2O·sec/L and mouth resistance measured with an oronasal mask was 4.5 cm H2O·sec/L; the two were not significantly different. Nose resistance measured with the oronasal mask was 7.6 cm H2O·sec/L. Adding airflow resistances of 1.12 and 2.10 cm H2O·sec/L to the breathing circuit between the mouth and APD yielded respiratory resistance values higher than the control by 0.7 and 2.0 cm H2O·sec/L. Although breathing through a 52 cm length of flexible ventilator tubing reduced the APD

  12. Single cell analysis of yeast replicative aging using a new generation of microfluidic device.

    Directory of Open Access Journals (Sweden)

    Yi Zhang

    Full Text Available A major limitation to yeast aging study has been the inability to track mother cells and observe molecular markers during the aging process. The traditional lifespan assay relies on manual micro-manipulation to remove daughter cells from the mother, which is laborious, time consuming, and does not allow long term tracking with high resolution microscopy. Recently, we have developed a microfluidic system capable of retaining mother cells in the microfluidic chambers while removing daughter cells automatically, making it possible to observe fluorescent reporters in single cells throughout their lifespan. Here we report the development of a new generation of microfluidic device that overcomes several limitations of the previous system, making it easier to fabricate and operate, and allowing functions not possible with the previous design. The basic unit of the device consists of microfluidic channels with pensile columns that can physically trap the mother cells while allowing the removal of daughter cells automatically by the flow of the fresh media. The whole microfluidic device contains multiple independent units operating in parallel, allowing simultaneous analysis of multiple strains. Using this system, we have reproduced the lifespan curves for the known long and short-lived mutants, demonstrating the power of the device for automated lifespan measurement. Following fluorescent reporters in single mother cells throughout their lifespan, we discovered a surprising change of expression of the translation elongation factor TEF2 during aging, suggesting altered translational control in aged mother cells. Utilizing the capability of the new device to trap mother-daughter pairs, we analyzed mother-daughter inheritance and found age dependent asymmetric partitioning of a general stress response reporter between mother and daughter cells.

  13. Nanostructured cavity devices for extracellular stimulation of HL-1 cells

    Science.gov (United States)

    Czeschik, Anna; Rinklin, Philipp; Derra, Ulrike; Ullmann, Sabrina; Holik, Peter; Steltenkamp, Siegfried; Offenhäusser, Andreas; Wolfrum, Bernhard

    2015-05-01

    Microelectrode arrays (MEAs) are state-of-the-art devices for extracellular recording and stimulation on biological tissue. Furthermore, they are a relevant tool for the development of biomedical applications like retina, cochlear and motor prostheses, cardiac pacemakers and drug screening. Hence, research on functional cell-sensor interfaces, as well as the development of new surface structures and modifications for improved electrode characteristics, is a vivid and well established field. However, combining single-cell resolution with sufficient signal coupling remains challenging due to poor cell-electrode sealing. Furthermore, electrodes with diameters below 20 µm often suffer from a high electrical impedance affecting the noise during voltage recordings. In this study, we report on a nanocavity sensor array for voltage-controlled stimulation and extracellular action potential recordings on cellular networks. Nanocavity devices combine the advantages of low-impedance electrodes with small cell-chip interfaces, preserving a high spatial resolution for recording and stimulation. A reservoir between opening aperture and electrode is provided, allowing the cell to access the structure for a tight cell-sensor sealing. We present the well-controlled fabrication process and the effect of cavity formation and electrode patterning on the sensor's impedance. Further, we demonstrate reliable voltage-controlled stimulation using nanostructured cavity devices by capturing the pacemaker of an HL-1 cell network.Microelectrode arrays (MEAs) are state-of-the-art devices for extracellular recording and stimulation on biological tissue. Furthermore, they are a relevant tool for the development of biomedical applications like retina, cochlear and motor prostheses, cardiac pacemakers and drug screening. Hence, research on functional cell-sensor interfaces, as well as the development of new surface structures and modifications for improved electrode characteristics, is a vivid and

  14. High-throughput microfluidic device for rare cell isolation

    Science.gov (United States)

    Yang, Daniel; Leong, Serena; Lei, Andy; Sohn, Lydia L.

    2015-06-01

    Enumerating and analyzing circulating tumor cells (CTCs)—cells that have been shed from primary solid tumors—can potentially be used to determine patient prognosis and track the progression of disease. There is a great challenge to create an effective platform that can isolate these cells, as they are extremely rare: only 1-10 CTCs are present in a 7.5mL of a cancer patient's peripheral blood. We have developed a novel microfluidic system that can isolate CTC populations label free. Our system consists of a multistage separator that employs inertial migration to sort cells based on size. We demonstrate the feasibility of our device by sorting colloids that are comparable in size to red blood cells (RBCs) and CTCs.

  15. Quantitative measurement of blood cells

    International Nuclear Information System (INIS)

    Full text: We are observing and measuring the varying development reaction stages of blood cells to different saline solutions. The imaging process is based on a common path interferometer which is realized with a spatial light modulator (SLM) in the Fourier plane after the microscope objective. With the SLM we can shift the phase of the transmitted light with respect to the phase of signal wave. This principle is used for the phase contrast microscopy method where we take four pictures of the same image with different phase shifts in order to calculate the complex field of the measured cell. This microscope technique obtains quantitative data about the blood cell's surface in different development stages, amplitude and phase differences inside the cell itself. (author)

  16. Infrared Emissivity Measurements of Building and Civil Engineering Materials: A New Device for Measuring Emissivity

    Science.gov (United States)

    Monchau, Jean-Pierre; Marchetti, Mario; Ibos, Laurent; Dumoulin, Jean; Feuillet, Vincent; Candau, Yves

    2014-10-01

    The knowledge of the infrared emissivity of materials used in buildings and civil engineering structures is useful for two specific approaches. First, quantitative diagnosis of buildings or civil engineering infrastructures by infrared thermography requires emissivity values in the spectral bandwidth of the camera used for measurements, in order to obtain accurate surface temperatures; for instance, emissivity in the band III domain is required when using cameras with uncooled detectors (such as micro-bolometer arrays). Second, setting up accurate thermal balances by numerical modeling requires the total emissivity value for a large wavelength domain; this is, for instance, the case for computing the road surface temperature to predict ice occurrence. Furthermore, periodical surveys of emissivity variations due to aging or soiling of surfaces could be useful in many situations such as thermal mapping of roads or building insulation diagnosis. The use of portable emissivity measurement devices is required for that purpose. A device using an indirect measurement method was previously developed in our lab; the method uses measurement of the reflectivity from a modulated IR source and requires calibration with a highly reflective surface. However, that device uses a low-frequency, thermal modulation well adapted to laboratory measurements but unfit for fast and in situ measurements. Therefore, a new, portable system which retains the principle of an indirect measurement but uses a faster-frequency, mechanical modulation more appropriate to outdoor measurements was developed. Both devices allow measurements in the broad m to m) and narrow m to m) bands. Experiments were performed on a large number of materials commonly used in buildings and civil engineering structures. The final objective of this work is to build a database of emissivity of these materials. A comparison of laboratory and on-site measurements of emissivity values obtained in both spectral bands will be

  17. Method and device for measuring the smoke concentration in air

    International Nuclear Information System (INIS)

    The patent deals with a method and a device for measuring the smoke concentration in air. In a smoke chamber are located two electrodes, connected to a voltage source for forming a circuit in which a DC current flows. A radioactive radiation source to ionize the air molecules is located in the vicinity of the smoke chamber, so that the number of ionized air molecules which are formed is dependent upon the radiation intensity of the ion source and the concentration of smoke particles in the smoke chamber. The charging voltage will further imply that a cloud of high ion concentration is built up close to the surface of the electrodes. The ion cloud will be discharged capacitively upon a plurality of short voltages pulses applied to the electrodes to thereby result in current pulses substantially greater than the DC current flowing through the chamber. 8 figs

  18. Novel dynamic fatigue-testing device: design and measurements

    Science.gov (United States)

    Foong, Chee-Hoe; Wiercigroch, Marian; Deans, William F.

    2006-08-01

    The influence of dynamics on a propagating fatigue crack has not been studied experimentally yet mainly due to quasi-static loading from traditional fatigue-testing machines. To overcome this serious drawback, a novel base-excited fatigue-testing device was designed and built to allow measurement of the dynamic responses of a single-edge-notch beam (SENB) under a growing fatigue crack. In this paper, the details of the novel test rig including initial development, modification and instrumentation are given. The experimental time histories obtained for harmonic and chaotic excitations have shown that the fatigue rig is capable of generating a wide range of loading patterns. Moreover, the experimental crack growth curves and features of the fracture surface have confirmed that the rig is capable of inducing proper fatigue cracks.

  19. Long-distance measurement-device-independent multiparty quantum communication.

    Science.gov (United States)

    Fu, Yao; Yin, Hua-Lei; Chen, Teng-Yun; Chen, Zeng-Bing

    2015-03-01

    The Greenberger-Horne-Zeilinger (GHZ) entanglement, originally introduced to uncover the extreme violation of local realism against quantum mechanics, is an important resource for multiparty quantum communication tasks. But the low intensity and fragility of the GHZ entanglement source in current conditions have made the practical applications of these multiparty tasks an experimental challenge. Here we propose a feasible scheme for practically distributing the postselected GHZ entanglement over a distance of more than 100 km for experimentally accessible parameter regimes. Combining the decoy-state and measurement-device-independent protocols for quantum key distribution, we anticipate that our proposal suggests an important avenue for practical multiparty quantum communication. PMID:25793788

  20. 21 CFR 882.1570 - Powered direct-contact temperature measurement device.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Powered direct-contact temperature measurement....1570 Powered direct-contact temperature measurement device. (a) Identification. A powered direct-contact temperature measurement device is a device which contains a power source and is used to...

  1. An electromagnetic cell-stretching device for mechanotransduction studies of olfactory ensheathing cells.

    Science.gov (United States)

    Harshad, Kamble; Jun, Myeongjun; Park, Sungsu; Barton, Matthew J; Vadivelu, Raja K; St John, James; Nguyen, Nam-Trung

    2016-06-01

    Olfactory ensheathing cells (OECs) are primary candidates for cell transplantation therapy to repair spinal cord injury (SCI). However, the post transplantation survival of these cells remains a major hurdle for a success using this therapy. Mechanical stimuli may contribute to the maintenance of these cells and thus, mechanotransduction studies of OECs may serve as a key benefit to identify strategies for improvement in cell transplantation. We developed an electromagnetic cell stretching device based on a single sided uniaxial stretching approach to apply tensile strain to OECs in culture. This paper reports the design, simulation and characterisation of the stretching device with preliminary experimental observations of OECs in vitro. The strain field of the deformable membrane was investigated both experimentally and numerically. Heterogeneity of the device provided an ideal platform for establishing strain requirement for the OEC culture. The cell stretching system developed may serve as a tool in exploring the mechanobiology of OECs for future SCI transplantation research. PMID:27194027

  2. Implantable Glucose BioFuel Cells for Medical Devices

    International Nuclear Information System (INIS)

    An Implantable BioFuel Cell (IBFC) is a device that produces power only from the chemicals that are naturally occurring inside the body. We have been working on two approaches to creating an IBFC. The first approach is to use chemicals such as glucose and oxygen to provide the fuel for an enzymatic IBFC. The second approach is to use electrolytes such as sodium to provide the fuel for a biomimetic IBFC

  3. Annealing of Solar Cells and Other Thin Film Devices

    Science.gov (United States)

    Escobar, Hector; Kuhlman, Franz; Dils, D. W.; Lush, G. B.; Mackey, Willie R. (Technical Monitor)

    2001-01-01

    Annealing is a key step in most semiconductor fabrication processes, especially for thin films where annealing enhances performance by healing defects and increasing grain sizes. We have employed a new annealing oven for the annealing of CdTe-based solar cells and have been using this system in an attempt to grow US on top of CdTe by annealing in the presence of H2S gas. Preliminary results of this process on CdTe solar cells and other thin-film devices will be presented.

  4. Measurement of subcellular texture by optical Gabor-like filtering with a digital micromirror device

    Science.gov (United States)

    Pasternack, Robert M.; Qian, Zhen; Zheng, Jing-Yi; Metaxas, Dimitris N.; White, Eileen; Boustany, Nada N.

    2010-01-01

    We demonstrate an optical Fourier processing method to quantify object texture arising from subcellular feature orientation within unstained living cells. Using a digital micromirror device as a Fourier spatial filter, we measured cellular responses to two-dimensional optical Gabor-like filters optimized to sense orientation of nonspherical particles, such as mitochondria, with a width around 0.45 μm. Our method showed significantly rounder structures within apoptosis-defective cells lacking the proapoptotic mitochondrial effectors Bax and Bak, when compared with Bax/Bak expressing cells functional for apoptosis, consistent with reported differences in mitochondrial shape in these cells. By decoupling spatial frequency resolution from image resolution, this method enables rapid analysis of nonspherical submicrometer scatterers in an under-sampled large field of view and yields spatially localized morphometric parameters that improve the quantitative assessment of biological function. PMID:18830354

  5. Quantum efficiency measurements in the swept charge device CCD236

    International Nuclear Information System (INIS)

    The e2v technologies plc. CCD236 is a Swept Charge Device (SCD) designed as a large area (20 mm × 20 mm) soft X-ray detector for spectroscopy in the range 0.8 keV to 10 keV. It benefits from improvements in design over the previous generation, the e2v CCD54, such as: a 4 times increased detector area, a reduction in split X-ray events due to the 100 μm × 100 μm 'pixel' size, and improvements to radiation hardness. The CCD236 will be used in India's Chandrayaan-2 Large Soft X-ray Spectrometer (CLASS) instrument and China's Hard X-ray Modulation Telescope (HXMT). Measurements of the Quantum Efficiency (QE) have been obtained relative to a NIST calibrated photodiode over the energy range 0.2 keV to 1.9 keV, using the BESSY II X-ray synchrotron in Berlin. Two X-ray event counting methods are described and compared, and QE for soft X-ray interaction is reported. Uniformity of QE across the device is also investigated at energies between 0.52 keV and 1.5 keV in different areas of the detector. This work will enable the actual number of photons incident on the detectors to be calculated, thus ensuring that the CCD236 detectors provide valuable scientific data during use. By comparing the QE methods in this paper with the event processing techniques to be used with CLASS, an estimate of the instrument-specific QE for CLASS can be provided

  6. Measurements of temperature and density in magnetic confinement fusion devices

    Science.gov (United States)

    Udintsev, Victor S.

    2010-11-01

    Controlled thermonuclear fusion can fulfil the demand of mankind to have an inexhaustible source of energy that does not cause any serious environmental pollution. The aim of fusion research is to build a continuously operating reactor in which the energy released by the fusion reactions is sufficiently high to keep the plasma hot and to produce more fusion reactions. The knowledge of the plasma temperature and density, together with the energy confinement time, is therefore very important for the effective control of the self-sustained fusion reactor. Various methods and diagnostics for measurements of the plasma temperature and density in present experimental fusion devices, as well as requirements for the future fusion reactors, will be discussed. A special attention will be given to the temperature and density diagnostics in ITER tokamak, which is presently under construction by several international partners at Cadarache in France. Development of these diagnostics is a major challenge because of severe environment, strict engineering requirements, safety issues and the need for high reliability in the measurements.

  7. Evaluation of spectrum measurement devices for operational use

    CERN Document Server

    Devine, R T; Gray, D W; Seagraves, D T; Olsher, R H; Johnson, J P

    2002-01-01

    Several neutron spectrometers manufactured by Bubble Technology Industries (BTI) were tested and evaluated in a variety of neutron fields. Findings and conclusions are presented for the following BTI instruments: a modification of the Rotational Spectrometer (ROSPEC) that includes a thermal and epithermal capability, the Simple Scintillation Spectrometer that is used in conjunction with the ROSPEC to extend its high-energy range, and the MICROSPEC N-Probe which is capable of providing a crude spectrum over the energy range from thermal to 18 MeV. The main objective of these measurements was to determine the accuracy of both the energy spectrum and dose equivalent information generated by these devices. In addition, the dose response of the Wide-Energy Neutron Detection Instrument (WENDI-II) was measured in all neutron fields relative to a bare sup 2 sup 5 sup 2 Cf calibration. The performance of the WENDI-II rem meter was compared to the dose information generated by the neutron spectrometers. The instruments...

  8. Evaluating the performance of microbial fuel cells powering electronic devices

    Energy Technology Data Exchange (ETDEWEB)

    Dewan, Alim; Beyenal, Haluk [Gene and Linda Voiland School of Chemical Engineering and Bioengineering, Center for Environmental, Sediment and Aquatic Research, Pullman, WA (United States); Donovan, Conrad; Heo, Deukhyoun [School of Electrical Engineering and Computer Science, Washington State University, Pullman, WA 99163-2710 (United States)

    2010-01-01

    A microbial fuel cell (MFC) is capable of powering an electronic device if we store the energy in an external storage device, such as a capacitor, and dispense that energy intermittently in bursts of high-power when needed. Therefore its performance needs to be evaluated using an energy-storing device such as a capacitor which can be charged and discharged rather than other evaluation techniques, such as continuous energy dissipation through a resistor. In this study, we develop a method of testing microbial fuel cell performance based on storing energy in a capacitor. When a capacitor is connected to a MFC it acts like a variable resistor and stores energy from the MFC at a variable rate. In practice the application of this method to testing microbial fuel cells is very challenging and time consuming; therefore we have custom-designed a microbial fuel cell tester (MFCT). The MFCT evaluates the performance of a MFC as a power source. It uses a capacitor as an energy storing device and waits until a desired amount of energy is stored then discharges the capacitor. The entire process is controlled using an analog-to-digital converter (ADC) board controlled by a custom-written computer program. The utility of our method and the MFCT is demonstrated using a laboratory microbial fuel cell (LMFC) and a sediment microbial fuel cell (SMFC). We determine (1) how frequently a MFC can charge a capacitor, (2) which electrode is current-limiting, (3) what capacitor value will allow the maximum harvested energy from a MFC, which is called the ''optimum charging capacitor value,'' and (4) what capacitor charging potential will harvest the maximum energy from a MFC, which is called the ''optimum charging potential.'' Using a LMFC we find that (1) the time needed to charge a 3-F capacitor from 0 to 500 mV is 108 min, (2) the optimum charging capacitor value is 3 F, and (3) the optimum charging potential is 300 mV. Using a SMFC we find that (1

  9. Development of microarray device for functional evaluation of PC12D cell axonal extension ability

    Science.gov (United States)

    Nakamachi, Eiji; Yanagimoto, Junpei; Murakami, Shinya; Morita, Yusuke

    2014-04-01

    In this study, we developed a microarray bio-MEMS device that could trap PC12D (rat pheochromocytoma cells) cells to examine the intercellular interaction effect on the cell activation and the axonal extension ability. This is needed to assign particular patterns of PC12D cells to establish a cell functional evaluation technique. This experimental observation-based technique can be used for design of the cell sheet and scaffold for peripheral and central nerve regeneration. We have fabricated a micropillar-array bio-MEMS device, whose diameter was approximately 10 μm, by using thick photoresist SU-8 on the glass slide substrate. A maximum trapped PC12D cell ratio, 48.5%, was achieved. Through experimental observation of patterned PC12D "bi-cells" activation, we obtained the following results. Most of the PC12D "bi-cells" which had distances between 40 and 100 μm were connected after 24 h with a high probability. On the other hand, "bi-cells" which had distances between 110 and 200 μm were not connected. In addition, we measured axonal extension velocities in cases where the intercellular distance was between 40 and 100 μm. A maximum axonal extension velocity, 86.4 μm/h, was obtained at the intercellular distance of 40 μm.

  10. Simple uniaxial pressure device for ac-susceptibility measurements suitable for closed cycle refrigerator system.

    Science.gov (United States)

    Arumugam, S; Manivannan, N; Murugeswari, A

    2007-06-01

    A simple design of the uniaxial pressure device for the measurement of ac-susceptibility at low temperatures using closed cycle refrigerator system is presented for the first time. This device consists of disc micrometer, spring holder attachment, uniaxial pressure cell, and the ac-susceptibility coil wound on stycast bobbin. It can work under pressure till 0.5 GPa and at the temperature range of 30-300 K. The performance of the system at ambient pressure is tested and calibrated with standard paramagnetic salts [Gd(2)O(3), Er(2)O(3), and Fe(NH(4)SO(4))(2)6H(2)O], Fe(3)O(4), Gd metal, Dy metal, superconductor (YBa(2)Cu(3)O(7)), manganite (La(1.85)Ba(0.15)MnO(3)), and spin glass material (Pr(0.8)Sr(0.2)MnO(3)). The performance of the uniaxial pressure device is demonstrated by investigating the uniaxial pressure dependence of La(1.85)Ba(0.15)MnO(3) single crystal with P||c axis. The Curie temperature (T(c)) decreases as a function of pressure with P||c axis (dT(c)dP(||c axis)=-11.65 KGPa) up to 46 MPa. The design is simple, is user friendly, and does not require pressure calibration. Measurement can even be made on thin and small size oriented crystals. The failure of the coil is remote under uniaxial pressure. The present setup can be used as a multipurpose uniaxial pressure device for the measurement of Hall effect and thermoelectric power with a small modification in the pressure cell. PMID:17614625

  11. Design and testing of an innovative solar radiation measurement device

    International Nuclear Information System (INIS)

    After review of studies conducted on the solar radiation measuring systems, a new innovative instrument that would help in measuring the accurate solar radiation on horizontal surfaces has been designed and tested. An advanced instrument with ease of use and high precision that would enable the user to take the readings in terms of solar intensity (W/m2) has been tested. Also, the innovative instrument can record instantaneous readings of the solar intensities as well as the averages value of the solar radiation flux during certain periods of time. The instrument based in its design on being programmed by programmable interfacing controller (PIC). Furthermore, the power supply circuit is fed by the solar energy cells and does not need an external power source.

  12. Design and testing of an innovative solar radiation measurement device

    Energy Technology Data Exchange (ETDEWEB)

    Badran, Omar; El-Tous, Yousif; Abdala, Wasfi [Faculty of Engineering Technology, Al-Balqa Applied University, Amman 11134 (Jordan); Al-Salaymeh, Ahmed [Mechanical Engineering Department, Faculty of Engineering and Technology, University of Jordan, Amman 11942 (Jordan)

    2010-08-15

    After review of studies conducted on the solar radiation measuring systems, a new innovative instrument that would help in measuring the accurate solar radiation on horizontal surfaces has been designed and tested. An advanced instrument with ease of use and high precision that would enable the user to take the readings in terms of solar intensity (W/m{sup 2}) has been tested. Also, the innovative instrument can record instantaneous readings of the solar intensities as well as the averages value of the solar radiation flux during certain periods of time. The instrument based in its design on being programmed by programmable interfacing controller (PIC). Furthermore, the power supply circuit is fed by the solar energy cells and does not need an external power source. (author)

  13. 78 FR 27441 - NIJ Evaluation of Hand-Held Cell Phone Detector Devices

    Science.gov (United States)

    2013-05-10

    ... of Justice Programs NIJ Evaluation of Hand-Held Cell Phone Detector Devices AGENCY: National...) is soliciting interest in supplying hand-held cell phone detector devices for participation in an... soliciting interest in supplying hand-held cell phone detector devices for participation in an evaluation...

  14. A simple indentation device for measuring micrometer-scale tissue stiffness

    Science.gov (United States)

    Levental, I.; Levental, K. R.; Klein, E. A.; Assoian, R.; Miller, R. T.; Wells, R. G.; Janmey, P. A.

    2010-05-01

    Mechanical properties of cells and extracellular matrices are critical determinants of function in contexts including oncogenic transformation, neuronal synapse formation, hepatic fibrosis and stem cell differentiation. The size and heterogeneity of biological specimens and the importance of measuring their mechanical properties under conditions that resemble their environments in vivo present a challenge for quantitative measurement. Centimeter-scale tissue samples can be measured by commercial instruments, whereas properties at the subcellular (nm) scale are accessible by atomic force microscopy, optical trapping, or magnetic bead microrheometry; however many tissues are heterogeneous on a length scale between micrometers and millimeters which is not accessible to most current instrumentation. The device described here combines two commercially available technologies, a micronewton resolution force probe and a micromanipulator for probing soft biological samples at sub-millimeter spatial resolution. Several applications of the device are described. These include the first measurement of the stiffness of an intact, isolated mouse glomerulus, quantification of the inner wall stiffness of healthy and diseased mouse aortas, and evaluation of the lateral heterogeneity in the stiffness of mouse mammary glands and rat livers with correlation of this heterogeneity with malignant or fibrotic pathology as evaluated by histology.

  15. Method and device for bio-impedance measurement with hard-tissue applications

    International Nuclear Information System (INIS)

    Bio-impedance measurements can be used to detect and monitor several properties of living hard-tissues, some of which include bone mineral density, bone fracture healing or dental caries detection. In this paper a simple method and hardware architecture for hard tissue bio-impedance measurement is proposed. The key design aspects of such architecture are discussed and a commercial handheld ac impedance device is presented that is fully certified to international medical standards. It includes a 4-channel multiplexer and is capable of measuring impedances from 10 kΩ to 10 MΩ across a frequency range of 100 Hz to 100 kHz with a maximum error of 5%. The device incorporates several user interface methods and a Bluetooth link for bi-directional wireless data transfer. Low-power design techniques have been implemented, ensuring the device exceeds 8 h of continuous use. Finally, bench test results using dummy cells consisting of parallel connected resistors and capacitors, from 10 kΩ to 10 MΩ and from 20 pF to 100 pF, are discussed

  16. Passive direct methanol fuel cells for portable electronic devices

    International Nuclear Information System (INIS)

    Due to the increasing demand for electricity, clean, renewable energy resources must be developed. Thus, the objective of the present study was to develop a passive direct methanol fuel cell (DMFC) for portable electronic devices. The power output of six dual DMFCs connected in series with an active area of 4 cm2 was approximately 600 mW, and the power density of the DMFCs was 25 mW cm-2. The DMFCs were evaluated as a power source for mobile phone chargers and media players. The results indicated that the open circuit voltage of the DMFC was between 6.0 V and 6.5 V, and the voltage under operating conditions was 4.0 V. The fuel cell was tested on a variety of cell phone chargers, media players and PDAs. The cost of energy consumption by the proposed DMFC was estimated to be USD 20 W-1, and the cost of methanol is USD 4 kW h. Alternatively, the local conventional electricity tariff is USD 2 kW h. However, for the large-scale production of electronic devices, the cost of methanol will be significantly lower. Moreover, the electricity tariff is expected to increase due to the constraints of fossil fuel resources and pollution. As a result, DMFCs will become competitive with conventional power sources.

  17. Particle Trajectories in Rotating Wall Cell Culture Devices

    Science.gov (United States)

    Ramachandran N.; Downey, J. P.

    1999-01-01

    Cell cultures are extremely important to the medical community since such cultures provide an opportunity to perform research on human tissue without the concerns inherent in experiments on individual humans. Development of cells in cultures has been found to be greatly influenced by the conditions of the culture. Much work has focused on the effect of the motions of cells in the culture relative to the solution. Recently rotating wall vessels have been used with success in achieving improved cellular cultures. Speculation and limited research have focused on the low shear environment and the ability of rotating vessels to keep cells suspended in solution rather than floating or sedimenting as the primary reasons for the improved cellular cultures using these devices. It is widely believed that the cultures obtained using a rotating wall vessel simulates to some degree the effect of microgravity on cultures. It has also been speculated that the microgravity environment may provide the ideal acceleration environment for culturing of cellular tissues due to the nearly negligible levels of sedimentation and shear possible. This work predicts particle trajectories of cells in rotating wall vessels of cylindrical and annular design consistent with the estimated properties of typical cellular cultures. Estimates of the shear encountered by cells in solution and the interactions with walls are studied. Comparisons of potential experiments in ground and microgravity environments are performed.

  18. Ultra-thin solid oxide fuel cells: Materials and devices

    Science.gov (United States)

    Kerman, Kian

    Solid oxide fuel cells are electrochemical energy conversion devices utilizing solid electrolytes transporting O2- that typically operate in the 800 -- 1000 °C temperature range due to the large activation barrier for ionic transport. Reducing electrolyte thickness or increasing ionic conductivity can enable lower temperature operation for both stationary and portable applications. This thesis is focused on the fabrication of free standing ultrathin (creative processing schemes to experimentally test devices in a high temperature dual environment chamber. We present a simple elastic model to determine stable buckling configurations for free standing oxide membranes. This guides the experimental methodology for Y 2O3-doped ZrO2 film processing, which enables tunable internal stress in the films. Using these criteria, we fabricate robust Y2O3-doped ZrO2 membranes on Si and composite polymeric substrates by semiconductor and micro-machining processes, respectively. Fuel cell devices integrating these membranes with metallic electrodes are demonstrated to operate in the 300 -- 500 °C range, exhibiting record performance at such temperatures. A model combining physical transport of electronic carriers in an insulating film and electrochemical aspects of transport is developed to determine the limits of performance enhancement expected via electrolyte thickness reduction. Free standing oxide heterostructures, i.e. electrolyte membrane and oxide electrodes, are demonstrated. Lastly, using Y2O3-doped ZrO2 and Gd2O 3-doped CeO2, novel electrolyte fabrication schemes are explored to develop oxide alloys and nanoscale compositionally graded membranes that are thermomechanically robust and provide added interfacial functionality. The work in this thesis advances experimental state-of-the-art with respect to solid oxide fuel cell operation temperature, provides fundamental boundaries expected for ultrathin electrolytes, develops the ability to integrate highly dissimilar

  19. Single Glucose Biofuel Cells Implanted in Rats Power Electronic Devices

    OpenAIRE

    Zebda, A.; Cosnier, S.; J.-P. Alcaraz; Holzinger, M.; A. Le Goff; Gondran, C.; Boucher, F.; Giroud, F.; Gorgy, K.; Lamraoui, H.; Cinquin, P.

    2013-01-01

    We describe the first implanted glucose biofuel cell (GBFC) that is capable of generating sufficient power from a mammal's body fluids to act as the sole power source for electronic devices. This GBFC is based on carbon nanotube/enzyme electrodes, which utilize glucose oxidase for glucose oxidation and laccase for dioxygen reduction. The GBFC, implanted in the abdominal cavity of a rat, produces an average open-circuit voltage of 0.57 V. This implanted GBFC delivered a power output of 38.7 μW...

  20. Light induced polaron formation in perovskite solar cell devices

    Science.gov (United States)

    Neukirch, Amanda; Nie, Wanyi; Blancon, Jean-Christophe; Appavoo, Kannatassen; Tsai, Hsinhan; Chhowalla, Manish; Alam, Muhammad; Sfeir, Matthew; Katan, Claudine; Even, Jacky; Crochet, Jared; Gupta, Gautum; Mohite, Aditya; Tretiak, Sergei

    The need for a low-cost, clean, and abundant source of energy has generated large amounts of research in solution processed solar cell materials. The lead halide perovskite has rapidly developed as a serious candidate for the active layer of photovoltaic devices. The efficiencies of devices made with this material have increased from 3.5% to over 20% in around 5 years. Despite the remarkable progress associated with perovskite materials, there are still fundamental questions regarding their lack of photo-stability over prolonged solar irradiation that need to be addressed. Recent experiments on photo-degradation under constant illumination have found fast self-healing by resting the device in the dark for less than 1 minute. Density functional theory and symmetry analysis show that localized charge states couple to local structural lattice distortions and methyl ammonium quasistatic configurations. Once translational symmetry is lost, additional bonding configurations become symmetry allowed, triggering localized charges in the vicinity over time under constant illumination, thus seeding the formation of macroscopic charged domains and preventing efficient charge extraction. Here we present an in-depth study of polaron formation and binding energy at the atomistic level.

  1. Dielectric response of doped organic semiconductor devices: P3HT:PCBM solar cells

    Science.gov (United States)

    Armbruster, Oskar; Lungenschmied, Christoph; Bauer, Siegfried

    2011-08-01

    We introduce a model to account for the dielectric response of doped organic semiconductor devices. In addition to the phenomena observed for undoped devices, mobile charge carriers created by doping can alter the dielectric function of the organic material and hence the dielectric response of the devices. These extrinsic charges may be trapped and contribute to the capacitance on re-emission. We directly model the real part of the dielectric function based on this phenomenon. The imaginary part is obtained via the application of the Kramers-Kronig transformation. We use oxygen-doped poly(3-hexylthiophene):[6,6]-phenyl-C61-butyric acid methyl ester- (P3HT:PCBM) based organic solar cells as a model system to test our approach and hence contribute to the understanding of oxygen-induced degradation in these devices. We fit our equations to the measured dielectric data and compare it to Debye relaxation as well as two widely used equivalent circuit models. Together with the device resistance determined from the steady-state current-voltage characteristic around 0V an excellent agreement between the experimental data and our model is achieved for both the real and the imaginary part of the dielectric function over a frequency range covering five orders of magnitude. Unlike the Debye relaxation model or the equivalent circuit approach, our model yields important device parameters such as the dopant concentration.

  2. Relating Direct Methanol Fuel Cell Performance to Measurements in a Liquid Half Cell

    DEFF Research Database (Denmark)

    Pedersen, Christoffer Mølleskov; Tynelius, Oskar; Lund-Olesen, Torsten;

    2015-01-01

    allow further miniaturization or powering more advanced and more power hungry devices. The activity of fuel cell catalysts is often probed in the form of thin films in liquid half cells. However, it is challenging to mimic the conditions in an actual DMFC. On the other hand, it can also be problematic...... to extract the catalyst activity from a fuel cell measurement. In this work, we attempt to narrow the gap between fuel cell testing and liquid half-cell measurements. First, by placing a custom reference electrode within the fuel cell, we can determine the potential at the anode and cathode under in......-operando conditions. This in turn, allows us to directly correlate our measurements to those performed in a liquid half-cell at the same potential. For our half-cell measurements, we have tested different catalysts (Pt/C, PtRu/C) for the methanol oxidation reaction (MOR) and the oxygen reduction reaction (ORR...

  3. A microfluidic device integrating plasmonic nanodevices for Raman spectroscopy analysis on trapped single living cells

    KAUST Repository

    Perozziello, Gerardo

    2013-11-01

    In this work we developed a microfluidic device integrating nanoplasmonic devices combined with fluidic trapping regions. The microfuidic traps allow to capture single cells in areas where plasmonic sensors are placed. In this way it is possible to perform Enhanced Raman analysis on the cell membranes. Moreover, by changing direction of the flux it is possible to change the orientation of the cell in the trap, so that it is possible to analyze different points of the membrane of the same cell. We shows an innovative procedure to fabricate and assembly the microfluidic device which combine photolithography, focused ion beam machining, and hybrid bonding between a polymer substrate and lid of Calcium fluoride. This procedure is compatible with the fabrication of the plasmonic sensors in close proximity of the microfluidic traps. Moreover, the use of Calcium fluoride as lid allows full compatibility with Raman measurements producing negligible Raman background signal and avoids Raman artifacts. Finally, we performed Raman analysis on cells to monitor their oxidative stress under particular non physiological conditions. © 2013 Elsevier B.V. All rights reserved.

  4. Design and Functional Validation of a Complex Impedance Measurement Device for Characterization of Ultrasonic Transducers

    International Nuclear Information System (INIS)

    This paper presents the design and practical implementation of a complex impedance measurement device capable of characterization of ultrasonic transducers. The device works in the frequency range used by industrial ultrasonic transducers which is below the measurement range of modern high end network analyzers. The device uses the Goertzel algorithm instead of the more common FFT algorithm to calculate the magnitude and phase component of the impedance under test. A theoretical overview is given followed by a practical approach and measurement results. (authors)

  5. Cancer Cell Analyses at the Single Cell-Level Using Electroactive Microwell Array Device.

    Directory of Open Access Journals (Sweden)

    Marina Kobayashi

    Full Text Available Circulating tumor cells (CTCs, shed from primary tumors and disseminated into peripheral blood, are playing a major role in metastasis. Even after isolation of CTCs from blood, the target cells are mixed with a population of other cell types. Here, we propose a new method for analyses of cell mixture at the single-cell level using a microfluidic device that contains arrayed electroactive microwells. Dielectrophoretic (DEP force, induced by the electrodes patterned on the bottom surface of the microwells, allows efficient trapping and stable positioning of single cells for high-throughput biochemical analyses. We demonstrated that various on-chip analyses including immunostaining, viability/apoptosis assay and fluorescent in situ hybridization (FISH at the single-cell level could be conducted just by applying specific reagents for each assay. Our simple method should greatly help discrimination and analysis of rare cancer cells among a population of blood cells.

  6. An information-measuring system for evaluating performance parameters of lighting devices

    Science.gov (United States)

    Abulkhanov, Stanislav R.; Kharitonov, Sergey I.

    2016-04-01

    We propose the design of an information-measuring system for evaluating performance parameters of lighting devices. The system comprises four basic components: a software-hardware complex for designing lighting devices, an emulator of natural and technogeneous effects on an optical surface, an optical surface condition analyzer, and a lighting-device laboratory test unit. With this system, the duration of optical device certification tests can be reduced by several orders of magnitude when compared to full-scale tests.

  7. Comparing pulmonary resistance measured with an esophageal balloon to resistance measurements with an airflow perturbation device

    International Nuclear Information System (INIS)

    The airflow perturbation device (APD) perturbs flow and mouth pressure during regular breathing. Ratios of mouth pressure perturbation magnitudes to flow perturbation magnitudes were used to calculate inspiratory, expiratory and average respiratory resistances. Resistance measurements with the APD were compared to pulmonary resistances directly measured with an esophageal balloon. Six healthy subjects were tested during tidal breathing when known external resistances were added during inspiration, during expiration and during both inspiration and expiration. When the baseline averaged balloon measured pulmonary resistance was subtracted from the baseline averaged APD measured resistance, the difference between them was 0.92 ± 1.25 (mean ± SD) cmH2O L–1 s–1. Compared to the magnitude of the known increase in the added resistance, the APD measured resistance increased by 79%, whereas directly measured pulmonary resistance increased only by 56%. During addition of external resistances to both inspiration and expiration, the changes in inspiratory and expiratory pulmonary resistance were only 36% and 62% of the added resistance, respectively. On the other hand, the APD inhalation and exhalation resistance measured between 82% and 76% of the added resistance. We conclude that the APD detects changes in external resistance at least as well as, and probably better than, classical measurements of pulmonary resistance

  8. Semi-empirical device model for Cu2ZnSn(S,Se)4 solar cells

    Science.gov (United States)

    Gokmen, Tayfun; Gunawan, Oki; Mitzi, David B.

    2014-07-01

    We present a device model for the hydrazine processed kesterite Cu2ZnSn(S,Se)4 (CZTSSe) solar cell with a world record efficiency of ˜12.6%. Detailed comparison of the simulation results, performed using wxAMPS software, to the measured device parameters shows that our model captures the vast majority of experimental observations, including VOC, JSC, FF, and efficiency under normal operating conditions, and temperature vs. VOC, sun intensity vs. VOC, and quantum efficiency. Moreover, our model is consistent with material properties derived from various techniques. Interestingly, this model does not have any interface defects/states, suggesting that all the experimentally observed features can be accounted for by the bulk properties of CZTSSe. An electrical (mobility) gap that is smaller than the optical gap is critical to fit the VOC data. These findings point to the importance of tail states in CZTSSe solar cells.

  9. Capacitive Cells for Dielectric Constant Measurement

    Science.gov (United States)

    Aguilar, Horacio Munguía; Maldonado, Rigoberto Franco

    2015-01-01

    A simple capacitive cell for dielectric constant measurement in liquids is presented. As an illustrative application, the cell is used for measuring the degradation of overheated edible oil through the evaluation of their dielectric constant.

  10. Quantitative Electrochemical Measurements using in situ ec-S/TEM Devices

    Energy Technology Data Exchange (ETDEWEB)

    Unocic, Raymond R [ORNL; Sacci, Robert L [ORNL; Brown, Gilbert M [ORNL; Veith, Gabriel M [ORNL; Dudney, Nancy J [ORNL; More, Karren Leslie [ORNL; Gardiner, Daniel [Protochips Inc., Raleigh, NC; Walden II, Franklin S [Protochips Inc., Raleigh, NC; Damiano, John [Protochips Inc., Raleigh, NC; Nackashi, David P. [Protochips Inc., Raleigh, NC

    2014-01-01

    Insight into dynamic electrochemical processes can be obtained with in situ ec-S/TEM, which utilizes microfluidic electrochemical cells to characterize electrochemical processes with S/TEM imaging, diffraction or spectroscopy. The microfluidic electrochemical cell is composed of microfabricated devices with glassy carbon and platinum microband electrodes in a three-electrode cell configuration. To establish the validity of this method for quantitative in situ electrochemistry research, cyclic voltammetry, choronoamperometry and electrochemical impedance spectroscopy were performed using a standard one electron transfer redox couple using a [Fe(CN)6]3-/4- based electrolyte. Established relationships of the electrode geometry and microfluidic conditions were fitted with cyclic voltammetry and chronoamperometic measurements of analyte diffusion coefficients and was found to agree with well-accepted values that are on the order of 10-5 cm2 s-1. Influence of the electron beam on electrochemical measurements was found to be negligible during CV scans where the current profile varied only within a few nA with the electron beam on and off which is well within the hysteresis between multiple CV scans. The combination of experimental results provides a validation that quantitative electrochemistry experiments can be performed with these small-scale microfluidic electrochemical cells provided that accurate geometrical electrode configurations, diffusion boundary layers and microfluidic conditions are accounted for.

  11. Single Glucose Biofuel Cells Implanted in Rats Power Electronic Devices

    Science.gov (United States)

    Zebda, A.; Cosnier, S.; Alcaraz, J.-P.; Holzinger, M.; Le Goff, A.; Gondran, C.; Boucher, F.; Giroud, F.; Gorgy, K.; Lamraoui, H.; Cinquin, P.

    2013-01-01

    We describe the first implanted glucose biofuel cell (GBFC) that is capable of generating sufficient power from a mammal's body fluids to act as the sole power source for electronic devices. This GBFC is based on carbon nanotube/enzyme electrodes, which utilize glucose oxidase for glucose oxidation and laccase for dioxygen reduction. The GBFC, implanted in the abdominal cavity of a rat, produces an average open-circuit voltage of 0.57 V. This implanted GBFC delivered a power output of 38.7 μW, which corresponded to a power density of 193.5 μW cm−2 and a volumetric power of 161 μW mL−1. We demonstrate that one single implanted enzymatic GBFC can power a light-emitting diode (LED), or a digital thermometer. In addition, no signs of rejection or inflammation were observed after 110 days implantation in the rat. PMID:23519113

  12. PV cell and module performance measurement capabilities at NREL

    Energy Technology Data Exchange (ETDEWEB)

    Rummel, S.; Emery, K.; Field, H.; Moriarty, T.; Anderberg, A.; Dunlavy, D.; Ottoson, L.

    1998-09-01

    The Photovoltaic (PV) Cell and Module Performance Characterization team at NREL supports the entire photovoltaic community by providing: secondary calibrations of photovoltaic cells and modules; efficiency measurements with respect to a given set of standard reporting conditions; verification of contract efficiency milestones; and current versus voltage (I-V) measurements under various conditions of temperature, spectral irradiance, and total irradiance. Support is also provided to in-house programs in device fabrication, module stability, module reliability, PV systems evaluations, and alternative rating methods by performing baseline testing, specialized measurements and other assistance when required. The I-V and spectral responsivity equipment used to accomplish these tasks are described in this paper.

  13. Design and dynamic analysis of single-axis integrated inertia measurement device

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The structure and measurement theory of a single-axis integrated inertia measurement device are discussed in this paper.The acceleration and angle velocity can be detected by the proposed sensor at the same time.The kinetic model of the device is also established.In addition,the signal generation of the single-axis integrated inertiameasurement device is analyzed and simulated.The results of the model are consistent with simulation result.

  14. A simple microfluidic device for the deformability assessment of blood cells in a continuous flow.

    Science.gov (United States)

    Rodrigues, Raquel O; Pinho, Diana; Faustino, Vera; Lima, Rui

    2015-12-01

    Blood flow presents several interesting phenomena in microcirculation that can be used to develop microfluidic devices capable to promote blood cells separation and analysis in continuous flow. In the last decade there have been numerous microfluidic studies focused on the deformation of red blood cells (RBCs) flowing through geometries mimicking microvessels. In contrast, studies focusing on the deformation of white blood cells (WBCs) are scarce despite this phenomenon often happens in the microcirculation. In this work, we present a novel integrative microfluidic device able to perform continuous separation of a desired amount of blood cells, without clogging or jamming, and at the same time, capable to assess the deformation index (DI) of both WBCs and RBCs. To determine the DI of both WBCs and RBCs, a hyperbolic converging microchannel was used, as well as a suitable image analysis technique to measure the DIs of these blood cells along the regions of interest. The results show that the WBCs have a much lower deformability than RBCs when subjected to the same in vitro flow conditions, which is directly related to their cytoskeleton and nucleus contents. The proposed strategy can be easily transformed into a simple and inexpensive diagnostic microfluidic system to simultaneously separate and assess blood cells deformability. PMID:26482154

  15. High-rate measurement-device-independent quantum cryptography

    DEFF Research Database (Denmark)

    Pirandola, Stefano; Ottaviani, Carlo; Spedalieri, Gaetana;

    2015-01-01

    Quantum cryptography achieves a formidable task - the remote distribution of secret keys by exploiting the fundamental laws of physics. Quantum cryptography is now headed towards solving the practical problem of constructing scalable and secure quantum networks. A significant step in this direction...... than those currently achieved. Our protocol could be employed to build high-rate quantum networks where devices securely connect to nearby access points or proxy servers....

  16. Characterisation of oxygen permeation into a microfluidic device for cell culture by in situ NMR spectroscopy.

    Science.gov (United States)

    Yilmaz, Ali; Utz, Marcel

    2016-05-24

    A compact microfluidic device for perfusion culture of mammalian cells under in situ metabolomic observation by NMR spectroscopy is presented. The chip is made from poly(methyl methacrylate) (PMMA), and uses a poly(dimethyl siloxane) (PDMS) membrane to allow gas exchange. It is integrated with a generic micro-NMR detector developed recently by our group [J. Magn. Reson., 2016, 262, 73-80]. While PMMA is an excellent material in the context of NMR, PDMS is known to produce strong background signals. To mitigate this, the device keeps the PDMS away from the detection area. The oxygen permeation into the device is quantified using a flow chemistry approach. A solution of glucose is mixed on the chip with a solution of glucose oxidase, before flowing through the gas exchanger. The resulting concentration of gluconate is measured by (1)H NMR spectroscopy as a function of flow rate. An oxygen equilibration rate constant of 2.4 s(-1) is found for the device, which is easily sufficient to maintain normoxic conditions in a cell culture at low perfusion flow rates. PMID:27149932

  17. 30 CFR 75.320 - Air quality detectors and measurement devices.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Air quality detectors and measurement devices... quality detectors and measurement devices. (a) Tests for methane shall be made by a qualified person with... tests for oxygen deficiency required by the regulations in this part. Permissible flame safety lamps...

  18. Radiometric modulation measuring device of intensity of optical radiation

    Directory of Open Access Journals (Sweden)

    A. P. Yanenko

    2014-04-01

    Full Text Available Introduction. The paper proposed a block diagram of radiometric measuring the intensity of optical radiation from modulation conversion parameter input . To assess the intensity of use periodically comparing the reference signal (shaded and measurement (open photodi-odes. Studies. The proposed radiometric modulation meter provides increased sensitivity and measurement accuracy by reducing the influence of dark current measurement and reference photodiodes and compensation intrinsic noise measuring channel through their periodic anti-phase comparison.

  19. Automated measurement of cell motility and proliferation

    Directory of Open Access Journals (Sweden)

    Goff Julie

    2005-04-01

    Full Text Available Abstract Background Time-lapse microscopic imaging provides a powerful approach for following changes in cell phenotype over time. Visible responses of whole cells can yield insight into functional changes that underlie physiological processes in health and disease. For example, features of cell motility accompany molecular changes that are central to the immune response, to carcinogenesis and metastasis, to wound healing and tissue regeneration, and to the myriad developmental processes that generate an organism. Previously reported image processing methods for motility analysis required custom viewing devices and manual interactions that may introduce bias, that slow throughput, and that constrain the scope of experiments in terms of the number of treatment variables, time period of observation, replication and statistical options. Here we describe a fully automated system in which images are acquired 24/7 from 384 well plates and are automatically processed to yield high-content motility and morphological data. Results We have applied this technology to study the effects of different extracellular matrix compounds on human osteoblast-like cell lines to explore functional changes that may underlie processes involved in bone formation and maintenance. We show dose-response and kinetic data for induction of increased motility by laminin and collagen type I without significant effects on growth rate. Differential motility response was evident within 4 hours of plating cells; long-term responses differed depending upon cell type and surface coating. Average velocities were increased approximately 0.1 um/min by ten-fold increases in laminin coating concentration in some cases. Comparison with manual tracking demonstrated the accuracy of the automated method and highlighted the comparative imprecision of human tracking for analysis of cell motility data. Quality statistics are reported that associate with stage noise, interference by non-cell

  20. Measurement of active shoulder proprioception: dedicated system and device

    OpenAIRE

    Lubiatowski, Przemyslaw; Ogrodowicz, Piotr; Wojtaszek, Marcin; Kaniewski, Ryszard; Stefaniak, Jakub; Dudziński, Witold; Romanowski, Leszek

    2012-01-01

    Proprioception is an essential part of shoulder stability and neuromuscular control. The purpose of the study was the development of a precise system of shoulder proprioception assessment in the active mode (Propriometr). For that purpose, devices such as the electronic goniometer and computer software had been designed. A pilot study was carried out on a control group of 27 healthy subjects, the average age being 23.8 (22–29) in order to test the system. The result of the assessment was the ...

  1. Noninvasive Diagnostic Devices for Diabetes through Measuring Tear Glucose

    OpenAIRE

    Zhang, Jin; Hodge, William; Hutnick, Cindy; Wang, Xianbin

    2011-01-01

    This article reviews the development of a noninvasive diagnostic for diabetes by detecting ocular glucose. Early diagnosis and daily management are very important to diabetes patients to ensure a healthy life. Commercial blood glucose sensors have been used since the 1970s. Millions of diabetes patients have to prick their finger for a drop of blood 4–5 times a day to check blood glucose levels—almost 1800 times annually. There is a strong need to have a noninvasive device to help patients to...

  2. Mathematical Model of an Inductive Measuring Cell for Contactless Conductometry

    CERN Document Server

    Semenov, Yury S

    2013-01-01

    A research of inductive conductometric cell is presented. An equivalent circuit and a mathematical model of inductive cell are given in the article. The model takes into account sample-coil capacity (i.e. capacity formed by the coil and the sample under study) and eddy currents. It is sample-coil capacity that makes inductive cell applicable for measurement of electrical conductivity of low conductive samples (specific conductance is less than 1S/m). The model can be used to calculate impedance of inductive cell for different characteristics of sample, materials and dimensions of cell without numerical solving of partial differential equations. Results of numerical simulation were verified by experiment for several devices with inductive cell. Some features that an engineer has to hold in mind while designing a conductometer based on inductive cell are discussed. Presented model can be useful for those who study inductively coupled plasma.

  3. Development of a device to measure coolant flow within CAGR instrumented fuel stringers

    International Nuclear Information System (INIS)

    This paper is concerned with the development work that has been carried out to design a device for the measurement of reactor channel flows and discusses some of the important considerations in terms of design limitations, measurement reliability and accuracy. Various prototype design concepts were studied, with the venturi tube finally adopted as the primary flow measurement device. Incorporation of a venturi tube within a CAGR fuel stringer presents some design difficulties and the consequent form of the device does not adhere to the British Standard. A procedure has therefore been developed for individual calibration and for the derivation of device discharge coefficients over the relevant range of reactor coolant flow conditions. This procedure is described and an appreciation given for the accuracies that can be achieved for venturi tubes used as flow measurement devices in CAGR fuel channels

  4. Rapid Impedance Spectrum Measurements for State-of-Health Assessment of Energy Storage Devices

    Energy Technology Data Exchange (ETDEWEB)

    Jon P. Christophersen; John L. Morrison; Chester G. Motloch; William H. Morrison

    2012-04-01

    Harmonic compensated synchronous detection (HCSD) is a technique that can be used to measure wideband impedance spectra within seconds based on an input sum-of-sines signal having a frequency spread separated by harmonics. The battery (or other energy storage device) is excited with a sum-of-sines current signal that has a duration of at least one period of the lowest frequency. The voltage response is then captured and synchronously detected at each frequency of interest to determine the impedance spectra. This technique was successfully simulated using a simplified battery model and then verified with commercially available Sanyo lithium-ion cells. Simulations revealed the presence of a start-up transient effect when only one period of the lowest frequency is included in the excitation signal. This transient effect appears to only influence the low-frequency impedance measurements and can be reduced when a longer input signal is used. Furthermore, lithium-ion cell testing has indicated that the transient effect does not seem to impact the charge transfer resistance in the mid-frequency region. The degradation rates for the charge transfer resistance measured from the HCSD technique were very similar to the changes observed from standardized impedance spectroscopy methods. Results from these studies, therefore, indicate that HCSD is a viable, rapid alternative approach to acquiring impedance spectra.

  5. Electrical impedance spectroscopy device for measurement of moisture gradients in wood

    Science.gov (United States)

    Tiitta, M.; Olkkonen, H.

    2002-08-01

    A prototype of the electrical impedance spectroscopy (EIS) device for the measurement of internal moisture gradients in wood was developed. The EIS device consists of a hand-held probe connected to a control unit interfaced with a portable personal computer and a power unit. In the measurement, parallel flat electrodes of the measuring probe are laid against the wood specimen and the sine wave excitation is applied in the frequency range 1-100 kHz. The measured amplitude and phase spectral data were analyzed using the model based on constant phase elements. A spectral analysis software package was designed for measurement of subsurface transverse moisture gradients. The EIS device was tested with many types of uniform, desorption, and absorption gradients in lumber, pulpwood, and log specimens from spruce, pine, and birch. The EIS device can be easily transferred in a small case allowing field measurements.

  6. Load measurement system with load cell lock-out mechanism

    Science.gov (United States)

    Le, Thang; Carroll, Monty; Liu, Jonathan

    1995-01-01

    In the frame work of the project Shuttle Plume Impingement Flight Experiment (SPIFEX), a Load Measurement System was developed and fabricated to measure the impingement force of Shuttle Reaction Control System (RCS) jets. The Load Measurement System is a force sensing system that measures any combination of normal and shear forces up to 40 N (9 lbf) in the normal direction and 22 N (5 lbf) in the shear direction with an accuracy of +/- 0.04 N (+/- 0.01 lbf) Since high resolution is required for the force measurement, the Load Measurement System is built with highly sensitive load cells. To protect these fragile load cells in the non-operational mode from being damaged due to flight loads such as launch and landing loads of the Shuttle vehicle, a motor driven device known as the Load Cell Lock-Out Mechanism was built. This Lock-Out Mechanism isolates the load cells from flight loads and re-engages the load cells for the force measurement experiment once in space. With this highly effective protection system, the SPIFEX load measurement experiment was successfully conducted on STS-44 in September 1994 with all load cells operating properly and reading impingement forces as expected.

  7. Feasibility of an in situ measurement device for bubble size and distribution.

    Science.gov (United States)

    Junker, Beth; Maciejak, Walter; Darnell, Branson; Lester, Michael; Pollack, Michael

    2007-09-01

    The feasibility of in situ measurement device for bubble size and distribution was explored. A novel in situ probe measurement system, the EnviroCam, was developed. Where possible, this probe incorporated strengths, and minimized weaknesses of historical and currently available real-time measurement methods for bubbles. The system was based on a digital, high-speed, high resolution, modular camera system, attached to a stainless steel shroud, compatible with standard Ingold ports on fermenters. Still frames and/or video were produced, capturing bubbles passing through the notch of the shroud. An LED light source was integral with the shroud. Bubbles were analyzed using customized commercially available image analysis software and standard statistical methods. Using this system, bubble sizes were measured as a function of various operating parameters (e.g., agitation rate, aeration rate) and as a function of media properties (e.g., viscosity, antifoam, cottonseed flour, and microbial/animal cell broths) to demonstrate system performance and its limitations. For selected conditions, mean bubble size changes qualitatively compared favorably with published relationships. Current instrument measurement capabilities were limited primarily to clear solutions that did not contain large numbers of overlapping bubbles. PMID:17566786

  8. Sensory perception threshold measurement: an evaluation of semiobjective testing devices.

    Science.gov (United States)

    Halar, E M; Hammond, M C; LaCava, E C; Camann, C; Ward, J

    1987-08-01

    Five semiobjective devices for testing sensory perception thresholds were concomitantly used on 36 normal subjects to determine normal threshold values, intersubject variability, and their correlation with age. The five devices include the Semmes-Weinstein monofilament (touch); three-point esthesiometer (two-point discrimination); Pfizer thermal tester (temperature); biothesiometer (vibration); and Optacon tactile tester (vibration). Each subject was tested at 12 upper extremity (UE) and ten lower extremity (LE) sites. The threshold was determined by the two-alternative forced choice method. Results showed that the mean threshold for each sensory perception modality in the UE sites was significantly lower than in the LE sites. The means of distally located sites for two-point discrimination and vibration thresholds were significantly lower than the means of the proximal sites in the UE. In the LE, touch perception threshold was significantly higher distally than proximally. Distally located nerves (median and ulnar) showed lower mean threshold values than proximally located nerves for two-point discrimination. There were also similar findings for the other sensory modalities in the UE and LE. The mean threshold of dermatomes showed significant variation across the trials for two-point discrimination and vibration sensation. Distally located dermatomes showed lower threshold values than those located proximally. The means of most sites tested for each sensory modality (except vibration tested by the Optacon) showed correlation with age. There was no difference in threshold values between men and women for any sensory modality. The mean values of standard deviation were provided for each peripheral sensory nerve and dermatome.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:3619613

  9. Bring-Your-Own-Device: Turning Cell Phones into Forces for Good

    Science.gov (United States)

    Imazeki, Jennifer

    2014-01-01

    Over the last few years, classroom response systems (or "clickers") have become increasingly common. Although most systems require students to use a standalone handheld device, bring-your-own-device (BYOD) systems allow students to use devices they already own (e.g., a cell phone, tablet or laptop) to submit responses via text message or…

  10. 40 CFR 1065.275 - N2O measurement devices.

    Science.gov (United States)

    2010-07-01

    ... CONTROLS ENGINE-TESTING PROCEDURES Measurement Instruments Nox and N2o Measurements § 1065.275 N2O... for any compensation algorithm is 0.0% (that is, no bias high and no bias low), regardless of the... and no bias low), regardless of the uncompensated signal's bias. Use appropriate analytical...

  11. A semi-automatic device for measuring osmotic pressures (1962)

    International Nuclear Information System (INIS)

    A cryoscopic apparatus for measuring osmotic pressure in small samples (0.1 ml) is described. The sample is frozen by air cooled dry ice or liquid nitrogen; the temperature is measured by a thermistor resistance and a recording millivoltmeter. (author)

  12. A Simple Laser-Based Device for Simultaneous Microbial Culture and Absorbance Measurement

    OpenAIRE

    Abrevaya, X. C.; Cortón, E.; Areso, O.; Mauas, P. J. D

    2012-01-01

    In this work we present a device specifically designed to study microbial growth with several applications related to environmental microbiology and other areas of research as astrobiology. The Automated Measuring and Cultivation device (AMC-d) enables semi-continuous absorbance measurements directly during cultivation. It can measure simultaneously up to 16 samples. Growth curves using low and fast growing microorganism were plotted, including: Escherichia coli, and Haloferax volcanii, an ha...

  13. A Simple Laser-Based Device for Simultaneous Microbial Culture and Absorbance Measurement

    CERN Document Server

    Abrevaya, X C; Areso, O; Mauas, P J D

    2012-01-01

    In this work we present a device specifically designed to study microbial growth with several applications related to environmental microbiology and other areas of research as astrobiology. The Automated Measuring and Cultivation device (AMC-d) enables semi-continuous absorbance measurements directly during cultivation. It can measure simultaneously up to 16 samples. Growth curves using low and fast growing microorganism were plotted, including: Escherichia coli, and Haloferax volcanii, an halophilic archaeon.

  14. Equipment interfaces for scanning-measuring semiautomatic devices with a M-220 computer

    International Nuclear Information System (INIS)

    Described is a communication equipment of scanning-measuring semi-automatic devices with the M-220 computer which permits to increase reliability of the information communicated by several orders as well as the rate of its introduction into the computer. A functional scheme is presented and operation of the main block of the communication equipment - 45-discharge eight-channel electron commutator constructed on the elements of the DTL-logics is considered. Information from the commutator in the computer is transmissed by means of coaxial communication cables through the cells of the DTL level agreement with transistor logic of the M-220 computer. The time of information recording in the buffer register constitutes 1 μA, and the time of its transmission to the computer constitutes 25-100 μs and depends on the computer state

  15. A pilot study of a new spectrophotometry device to measure tissue oxygen saturation

    International Nuclear Information System (INIS)

    Tissue oxygen saturation (SO2) measurements have the potential for far wider use than at present but are limited by device availability and portability for many potential applications. A device based on a small, low-cost general-purpose spectrophotometer (the Harrison device) might facilitate wider use. The aim of this study was to compare the Harrison device with a commercial instrument, the LEA O2C. Measurements were carried out on the forearm and finger of 20 healthy volunteers, using a blood pressure cuff on the upper arm to induce different levels of oxygenation. Repeatability of both devices was assessed, and the Bland–Altman method was used to assess agreement between them. The devices showed agreement in overall tracking of changes in SO2. Test–retest agreement for the Harrison device was worse than for O2C, with SD repeatability of 10.6% (forearm) or 18.6% (finger). There was no overall bias between devices, but mean (SD) difference of 1.2 (11.8%) (forearm) or 4.4 (11.5%) (finger) were outside of a clinically acceptable range. Disagreements were attributed to the stability of the Harrison probe and the natural SO2 variations across the skin surface increasing the random error. Therefore, though not equivalent to the LEA O2C, a probe redesign and averaged measurements may help establish the Harrison device as a low cost alternative. (paper)

  16. A measuring device for holograms from large volume bubble chambers

    International Nuclear Information System (INIS)

    Measuring full-size reconstructed holographic images of bubbles from a large bubble chamber presents problems of size, rapid location of the desired event, and precise measurement of a local region. We present a conceptual design of a practical system using computer-controlled mirrors to align the desired vertex region along the axis of motion of a vidicon whose field of view includes the local region. Precise measurements of short-decay paths are then made by fine adjustments of the vidicon position. This method requires normal stereo photography for scanning and preliminary reconstruction of the event. (orig.)

  17. Classification of methods for measuring current-voltage characteristics of semiconductor devices

    Directory of Open Access Journals (Sweden)

    Iermolenko Ia. O.

    2014-06-01

    Full Text Available It is shown that computer systems for measuring current-voltage characteristics are very important for semiconductor devices production. The main criteria of efficiency of such systems are defined. It is shown that efficiency of such systems significantly depends on the methods for measuring current-voltage characteristics of semiconductor devices. The aim of this work is to analyze existing methods for measuring current-voltage characteristics of semiconductor devices and to create the classification of these methods in order to specify the most effective solutions in terms of defined criteria. To achieve this aim, the most common classifications of methods for measuring current-voltage characteristics of semiconductor devices and their main disadvantages are considered. Automated and manual, continuous, pulse, mixed, isothermal and isodynamic methods for measuring current-voltage characteristics are analyzed. As a result of the analysis and generalization of existing methods the next classification criteria are defined: the level of automation, the form of measurement signals, the condition of semiconductor device during the measurements, and the use of mathematical processing of the measurement results. With the use of these criteria the classification scheme of methods for measuring current-voltage characteristics of semiconductor devices is composed and the most effective methods are specified.

  18. Method and device for measuring formation characteristics of geological formations

    International Nuclear Information System (INIS)

    A well-logging system is described which uses a pulsed neutron source and which by combining measurements of gamma spectra and neutron characteristics enables such parameters as salinity, porosity, water saturation, lithology and schistosity to be registered directly. (JIW)

  19. 27 CFR 19.277 - Measuring devices and proofing instruments.

    Science.gov (United States)

    2010-04-01

    ... those prescribed in 27 CFR part 30. Proprietors shall make frequent tests of their hydrometers and... person. (c) Meters. The appropriate TTB officer may approve applications to measure spirits by meter...

  20. Measurement of the Magnet Blocks for SSRF Insertion Devices

    International Nuclear Information System (INIS)

    Two in-vacuum undulators IVU25s and one elliptically polarized undulator EPU100 have been developed for SSRF. Two IVU25s with the same hybrid design contain about 640 Sm2Co17 magnet blocks and the dimension of blocks is 65 Wx25 Hx9 D. The EPU100 of the APPLE-II type contains about 690 NdFeB magnet blocks with the dimension of 35 Wx35 Hx25 D. This paper describes the magnetic measurements of these magnet blocks with the Helmholtz coil measurement system for IVU25 magnet blocks and the Hall probe measurement system for EPU100 magnet blocks. The measured maximum magnetic moment deviation and the maximum angle deviation are less than ±1.0% and 1.1 deg. respectively both for Sm2Co17 blocks and NdFeB blocks and satisfy the specifications of undulators.

  1. Process device for measuring the absorber rod position

    International Nuclear Information System (INIS)

    In gas-cooled high temperature reactors, the absorber rods can move in their longitudinal direction between two end positions. The position measurement is done indirectly by evaluating the movement of the mechanical elements of the rod drive. The translatory lifting movement of the absorber rod is converted into a rotation movement for measurement purposes and is transferred to at least two pulse transmitters per end position. (orig./HP)

  2. A Modular High-Temperature Measurement Set-Up for Semiconductor Device Characterization

    CERN Document Server

    Borthen, P

    2008-01-01

    We demonstrate the capabilities of a high temperature measurement set-up recently developed at our institute. It is dedicated to the characterization of semiconductor devices and test structures in the temperature range from room temperature up to 500 degrees C and higher. A detailed description of the experimental aquipment is given. Its practical use is demonstrated by measuring temperature-dependent charcteristics of silicon VDMOSFET and IGBT devices as well as SiC-diodes. For the silicon devices, numerical simulations based on recently developed high temperature physical models were also performed in order to gain a deeper understanding of the measured data, together with a revalidation of the model parameters.

  3. Experimental and theoretical study of hydrodynamic cell lysing of cancer cells in a high-throughput Circular Multi-Channel Microfiltration device

    KAUST Repository

    Ma, W.

    2013-04-01

    Microfiltration is an important microfluidic technique suitable for enrichment and isolation of cells. However, cell lysing could occur due to hydrodynamic damage that may be detrimental for medical diagnostics. Therefore, we conducted a systematic study of hydrodynamic cell lysing in a high-throughput Circular Multi-Channel Microfiltration (CMCM) device integrated with a polycarbonate membrane. HeLa cells (cervical cancer cells) were driven into the CMCM at different flow rates. The viability of the cells in the CMCM was examined by fluorescence microscopy using Acridine Orange (AO)/Ethidium Bromide (EB) as a marker for viable/dead cells. A simple analytical cell viability model was derived and a 3D numerical model was constructed to examine the correlation of between cell lysing and applied shear stress under varying flow rate and Reynolds number. The measured cell viability as a function of the shear stress was consistent with theoretical and numerical predictions when accounting for cell size distribution. © 2013 IEEE.

  4. Measurement campaign on connectivity of mesh networks formed by mobile devices

    DEFF Research Database (Denmark)

    Pietrarca, Beatrice; Sasso, Giovanni; Perrucci, Gian Paolo; Fitzek, Frank

    This paper reports the results of a measurement campaign on the connectivity level of mobile devices using Bluetooth (BT) to form cooperative mobile mesh networks. Such mobile mesh networks composed of mobile devices are the basis for any peer-to-peer communication like wireless grids or social...

  5. Noninvasive diagnostic devices for diabetes through measuring tear glucose.

    Science.gov (United States)

    Zhang, Jin; Hodge, William; Hutnick, Cindy; Wang, Xianbin

    2011-01-01

    This article reviews the development of a noninvasive diagnostic for diabetes by detecting ocular glucose. Early diagnosis and daily management are very important to diabetes patients to ensure a healthy life. Commercial blood glucose sensors have been used since the 1970s. Millions of diabetes patients have to prick their finger for a drop of blood 4-5 times a day to check blood glucose levels--almost 1800 times annually. There is a strong need to have a noninvasive device to help patients to manage the disease easily and painlessly. Instead of detecting the glucose in blood, monitoring the glucose level in other body fluids may provide a feasible approach for noninvasive diagnosis and diabetes control. Tear glucose has been studied for several decades. This article reviews studies on ocular glucose and its monitoring methods. Attempts to continuously monitor the concentration of tear glucose by using contact lens-based sensors are discussed as well as our current development of a nanostructured lens-based sensor for diabetes. This disposable biosensor for the detection of tear glucose may provide an alternative method to help patients manage the disease conveniently. PMID:21303640

  6. Certifying entangled measurements in a device-independent way

    CERN Document Server

    Vertesi, Tamas

    2011-01-01

    We study under which conditions it is possible to assert that a joint demolition measurement cannot be simulated by Local Operations and Classical Communication. More concretely, we consider a scenario where two parties, Alice and Bob, send each an unknown state to a third party, Charlie, who in turn interacts with the states in some undisclosed way and then announces an outcome. We show that, under the assumption that Alice and Bob know the dimensionality of their systems, there exist situations where the statistics of the outcomes reveals the nature of Charlie's measurement.

  7. New devices for radiation measurement and hazard control

    International Nuclear Information System (INIS)

    Four gauges developed lately in the Department of Radioisotope Instruments and methods are presented: Dosimetric stand SD-50B for fast control of surface contamination of hands, feet, and clothing; Tc-99m isotope gamma radiation gauge for continuous measurement of Tc-99m isotope in liquid from the energy range 60-180 keV; 131I radiation source activity controller KAI-1 for fast measurement of 131I activity on automatic production line; 131I source activity controller KAI-2 for checking up if source container leaving production line contains a 131I source. (author)

  8. Standard for nuclear-radiation moisture measuring devices

    International Nuclear Information System (INIS)

    The hydrophobic standard is destined for calibrating nuclear-radiation (thermal neutrons) moisture measuring instruments of the surface and depth measuring type. It consists of a pile of thin, alternating layers of moderating materials, as e.g. polyethylene, and metal, as e.g. magnesium. Both materials show no affinity towards moisture. The pile is dimensioned in a way that it offers an infinitely large mass of homogeneously distributed hydrogen to the instrument to be calibrated. The individual layers may exhibit equal or different thickness in order to be able to establish a calibration curve for the moisture content if different standards are used. (DG)

  9. Metastability of copper indium gallium diselenide polycrystalline thin film solar cell devices

    Science.gov (United States)

    Lee, Jinwoo

    High efficiency thin film solar cells have the potential for being a world energy solution because of their cost-effectiveness. Looking to the future of solar energy, there is the opportunity and challenge for thin film solar cells. The main theme of this research is to develop a detailed understanding of electronically active defect states and their role in limiting device performance in copper indium gallium diselenide (CIGS) solar cells. Metastability in the CIGS is a good tool to manipulate electronic defect density and thus identify its effect on the device performance. Especially, this approach keeps many device parameters constant, including the chemical composition, grain size, and interface layers. Understanding metastability is likely to lead to the improvement of CIGS solar cells. We observed systematic changes in CIGS device properties as a result of the metastable changes, such as increases in sub-bandgap defect densities and decreases in hole carrier mobilities. Metastable changes were characterized using high frequency admittance spectroscopy, drive-level capacitance profiling (DLCP), and current-voltage measurements. We found two distinctive capacitance steps in the high frequency admittance spectra that correspond to (1) the thermal activation of hole carriers into/out of acceptor defect and (2) a temperature-independent dielectric relaxation freeze-out process and an equivalent circuit analysis was employed to deduce the dielectric relaxation time. Finally, hole carrier mobility was deduced once hole carrier density was determined by DLCP method. We found that metastable defect creation in CIGS films can be made either by light-soaking or with forward bias current injection. The deep acceptor density and the hole carrier density were observed to increase in a 1:1 ratio, which seems to be consistent with the theoretical model of VCu-V Se defect complex suggested by Lany and Zunger. Metastable defect creation kinetics follows a sub-linear power law

  10. Localized corrosion information using high resolution measurement devices

    DEFF Research Database (Denmark)

    Ambat, Rajan

    2005-01-01

    microstructure, in particular the local electrochemical activities of several microstructural heterogeneities such as second phase particles and grain boundaries. The overall corrosion behaviour of the material is determined by the local interaction of several microstructural features. On the other hand in...... a system to control the solution flow at the tip. Through addition of reference and counter electrodes, the pipette system becomes a microscopic electrochemical cell, which can then be used with high precision to determine the electrochemical characteristics of the microstructural region of interest...

  11. Miniature bioelectric device accurately measures and telemeters temperature

    Science.gov (United States)

    Fryer, T. B.

    1966-01-01

    Miniature micropower solid-state circuit measures and telemeters the body temperature of laboratory animals over periods up to two years. The circuit employs a thermistor as a temperature sensing element and an fm transmitter. It is constructed from conventional discrete components or integrated circuits.

  12. Measuring device for effective multiplication factors of a fuel assembly

    Energy Technology Data Exchange (ETDEWEB)

    Ueda, Makoto

    1988-11-14

    Purpose: To measure the effective multiplication factor of a fuel assembly without using an external neutron source. Constitution: Neutron absorbers disposed on the surface of a fuel assembly incorporating a spontaneous neutron source so as to put the surface of the assembly therebetween is moved. As the neutron absorber, a cadmium plate is most suitable, but boron, gadolinium or disprosium may also be used. Neutron counting rate phi upon setting the distance between the neutron absorbers and the surface of the fuel assembly to greater than 2 cm and neutron counting rate phi' upon setting it to less than 2 cm are measured by neutron detectors. The effective multiplication factor of the fuel assembly is calculated based on the results of both of the measurements according to the following equation: K = (A(phi/phi')-1)/(AB(phi/phi'-1)) According to this method, exchange for the external neutron source is no more required, and the maintenance is easier and working efficiency is higher as compared with the prior art. Further, since phi/phi' can be determined in one identical detector in a short period of time, the measuring error can be reduced. (Horiuchi, T.).

  13. Radioimmunoassay to quantitatively measure cell surface immunoglobulins

    International Nuclear Information System (INIS)

    A radioimmunoassay techniques developed to quantitatively measure the presence of immunoglobulins on the surface of cells, is described. The amount of immunoglobulins found on different tumor cells varied from 200 to 1140 ng/106 cells. Determination of immunoglobulins on the peripheral lymphocytes obtained from different cancer patients varied between 340 to 1040 ng/106 cells. Cultured tumor cells, on the other hand, were found to contain negligible quantities of human IgG

  14. Evaluation of oscillometric and Doppler ultrasonic devices for blood pressure measurements in anesthetized and conscious dogs.

    Science.gov (United States)

    Vachon, Catherine; Belanger, Marie C; Burns, Patrick M

    2014-08-01

    Two non-invasive blood pressure (NIBP) devices (oscillometry and Doppler) were compared to invasive blood pressure using a Bland-Altman analysis, in anesthetized and conscious dogs. When considering the systolic arterial pressure only during general anesthesia, both NIBP devices slightly underestimated the systolic arterial blood pressure however the precision and the limits of agreement for the Doppler were of a greater magnitude. This indicates a worse clinical performance by the Doppler. The performance of both NIBP devices deteriorated as measured in conscious animals. In general, for the oscillometric device, determination of invasive diastolic and mean arterial pressures was better than the invasive systolic arterial pressure. Overall, the oscillometric device satisfied more of the criteria set by the American College of Veterinary Internal Medicine consensus statement. Based upon these results, the oscillometric device is more reliable than the Doppler in the determination of blood pressure in healthy medium to large breed dogs. PMID:24924217

  15. Microfluidic device to study cell transmigration under physiological shear stress conditions

    DEFF Research Database (Denmark)

    Kwasny, Dorota; Kiilerich-Pedersen, Katrine; Moresco, Jacob Lange;

    2011-01-01

    the membrane under flow conditions. The 3D environment of migrating cells is imitated by injecting cell adhesion proteins to coat the membrane in the device. We tested the developed device with Jurkat cells migration towards medium supplemented with serum, and with chemokine induced lymphocytes...... natural migration process. Here we describe a novel in vitro cell transmigration microfluidic assay, which mimicks physiological shear flow conditions in blood vessels. The device was designed to incorporate the principles of both the Boyden chamber and the shear flow chamber assay, i.e. migration through...... migration. The applied continuous flow of cell suspension and chemoattractant ensures that the concentration gradient is maintained in time and space. The cell adhesion proteins used to enhance cell migration in the device were fibronectin and VCAM-1. We successfully observed a multistep transmigration...

  16. Integrated microfluidic device for single-cell trapping and spectroscopy

    KAUST Repository

    Liberale, Carlo

    2013-02-13

    Optofluidic microsystems are key components towards lab-on-a-chip devices for manipulation and analysis of biological specimens. In particular, the integration of optical tweezers (OT) in these devices allows stable sample trapping, while making available mechanical, chemical and spectroscopic analyses.

  17. A Modular High-Temperature Measurement Set-Up for Semiconductor Device Characterization

    OpenAIRE

    Borthen, P.; Wachutka, G.

    2007-01-01

    We demonstrate the capabilities of a high temperature measurement set-up recently developed at our institute. It is dedicated to the characterization of semiconductor devices and test structures in the temperature range from room temperature up to 500 degrees C and higher. A detailed description of the experimental aquipment is given. Its practical use is demonstrated by measuring temperature-dependent charcteristics of silicon VDMOSFET and IGBT devices as well as SiC-diodes. For the silicon ...

  18. Calculation of response coefficient for low-level liquid radioactivity concentration measurement device

    International Nuclear Information System (INIS)

    Background: The on-line low-level liquid radioactivity concentration measurement device is designed for monitoring the radioactivity level of nuclear power plant waste water. The relation between the radioactivity concentration of 137Cs in the liquid of pipeline and the counting rate of measurement device, i.e. the response coefficient is must be known. It is generally given by experimental calibration. But the calibration is difficult for on-line measurement. Purpose: This paper attempts to study the response coefficient of on-line measurement device by calculation. Methods: The response coefficient is calculated by Monte Carlo method and in which gamma-ray transport processes in detection device are simulated. The response counts in Nal detector derived from 137Cs in the liquid are calculated. Results: The response coefficient of off-line measuring device is calculated firstly. The result is in good agreement with the experimental calibration and the difference is small than 3%. It is indicated that the method is correct and the calculation model is reasonable. Then, the response coefficient of on-line measuring devices is calculated according to the on-line measurement device design and the structure of Nal detector. The minimum detectable concentration is given according to the response coefficient and the background count rate. Conclusions: The response coefficient of on-line measurement device is 1.249×10-4 s-1·Bq-1·m3 and the minimum detectable concentration can reach (4-5)×103 Bq·m-3 when the thickness of lead shield is 80 mm. (authors)

  19. New terahertz dispersive device for single-shot spectral measurements of terahertz pulse

    International Nuclear Information System (INIS)

    A new terahertz dispersive device designed for single-shot spectral measurements of broadband terahertz pulses is proposed. With two-dimensional quasi-randomly distributed element design, the device exhibits approximately the dispersive property of single-order diffraction in far field. Its far-field diffraction pattern is experimentally verified employing a continuous terahertz source centered at 2.52 THz and a pyroelectric focal-plane-array camera, which is in good agreement with the numerical result. The device provides a new approach for direct single-shot spectral measurements of broadband terahertz waves. (physics of gases, plasmas, and electric discharges)

  20. Detection and measurement of electroreflectance on quantum cascade laser device using Fourier transform infrared microscope

    Energy Technology Data Exchange (ETDEWEB)

    Enobio, Eli Christopher I.; Ohtani, Keita; Ohno, Yuzo; Ohno, Hideo, E-mail: ohno@riec.tohoku.ac.jp [Laboratory for Nanoelectronics and Spintronics, Research Institute of Electrical Communication, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577 (Japan)

    2013-12-02

    We demonstrate the use of a Fourier Transform Infrared microscope system to detect and measure electroreflectance (ER) from mid-infrared quantum cascade laser (QCL) device. To characterize intersubband transition (ISBT) energies in a functioning QCL device, a microscope is used to focus the probe on the QCL cleaved mirror. The measured ER spectra exhibit resonance features associated to ISBTs under applied electric field in agreement with the numerical calculations and comparable to observed photocurrent, and emission peaks. The method demonstrates the potential as a characterization tool for QCL devices.

  1. Detection and measurement of electroreflectance on quantum cascade laser device using Fourier transform infrared microscope

    International Nuclear Information System (INIS)

    We demonstrate the use of a Fourier Transform Infrared microscope system to detect and measure electroreflectance (ER) from mid-infrared quantum cascade laser (QCL) device. To characterize intersubband transition (ISBT) energies in a functioning QCL device, a microscope is used to focus the probe on the QCL cleaved mirror. The measured ER spectra exhibit resonance features associated to ISBTs under applied electric field in agreement with the numerical calculations and comparable to observed photocurrent, and emission peaks. The method demonstrates the potential as a characterization tool for QCL devices

  2. Device for acoustic measurement of food texture using a piezoelectric sensor

    OpenAIRE

    Taniwaki, Mitsuru; Hanada, Takanori; Sakurai, Naoki

    2006-01-01

    We have developed a device that enables direct measurement of food texture. The device inserts a probe into a food sample and detects the vibration caused by the sample's fracture. A piezoelectric sensor was used to detect that vibration. The frequency response of the piezoelectric sensor was measured. Results showed that the sensor covered the full audio frequency range up to 20 kHz. The device probe was designed so that its resonance was not in the signal detection band. An octave multi-fil...

  3. Light collection optics for measuring flux and spectrum from light-emitting devices

    Science.gov (United States)

    McCord, Mark A.; DiRegolo, Joseph A.; Gluszczak, Michael R.

    2016-05-24

    Systems and methods for accurately measuring the luminous flux and color (spectra) from light-emitting devices are disclosed. An integrating sphere may be utilized to directly receive a first portion of light emitted by a light-emitting device through an opening defined on the integrating sphere. A light collector may be utilized to collect a second portion of light emitted by the light-emitting device and direct the second portion of light into the integrating sphere through the opening defined on the integrating sphere. A spectrometer may be utilized to measure at least one property of the first portion and the second portion of light received by the integrating sphere.

  4. Design and measurement of a four-port device using metamaterials.

    Science.gov (United States)

    Thomas, Zachary; Grzegorczyk, Tomasz; Wu, Bae-Ian; Chen, Xudong; Kong, Jin Au

    2005-06-13

    A band separating device that uses an anisotropic metamaterial exhibiting negative refraction is designed and measured. The metamaterial has frequency dispersion in one component of the permeability tensor. A beam is incident onto the metamaterial and undergoes frequency dependent reflection and refraction directing different bandwidths towards three distinct measurement ports. Design issues are discussed, and measurement results are presented. PMID:19495391

  5. Analysis of thermal neutron flux measurement in the Cobalt Irradiation Device at ETRR-2

    International Nuclear Information System (INIS)

    The measurements of geometrical distribution of thermal neutron flux in research reactors are often used in the field of reactor operation and reactor physics. Usually such measurements are carried out by using the gold wire activation method. This method has been used for measuring a thermal neutron flux at the location of a Cobalt Irradiation Device (CID) of ETRR-2. A special device was used for locating samples in an irradiation box and the measurements were preformed for seventy two positions. The Monte Carlo MCNP-4B code has been used for the modeling and simulation of ETRR-2 core with structural materials and surrounding beryllium reflectors. The device used in the flux measurement was also simulated in the MCNP-4B model. The thermal flux has been calculated and compared with the experimental one. The results show good agreement between the measured and calculated flux. (author)

  6. Experimental arrangement to measure dispersion in optical fiber devices

    International Nuclear Information System (INIS)

    Dispersion is a quite important parameter in systems based on optical fiber, especially in pulsed emission lasers, where the temporal width is affected by such parameter. Therefore, it is necessary to consider the dispersion provoked by each component in the cavity. There are various experimental interferometric arrangements to evaluate this parameter. Generally, these systems modify the wavelength to obtain information about the n(λ) dependency, which is contained in the interferogram phase. However, this makes the system quite slow and it requires tunable and narrow bandwidth laser sources. In the present work, results obtained from an arrangement based on Mach-Zehnder interferometer where one of the arms is the optical fiber under study, while the reference one is air, are presented. In order to determine the n(λ) dependency, a wide spectrum light source was used in the wavelength range of interest. The phase information was evaluated from the interferometric signal measured by an optical spectrum analyzer.

  7. Experimental arrangement to measure dispersion in optical fiber devices

    Energy Technology Data Exchange (ETDEWEB)

    Armas Rivera, Ivan [Benemerita Universidad Autonoma de Puebla, Facultad de Ciencias de la Electronica (Mexico); Beltran Perez, Georgina; Castillo Mixcoatl, Juan; Munoz Aguirre, Severino [Benemerita Universidad Autonoma de Puebla, Facultad de Ciencias Fisico Matematicas (Mexico); Zaca Moran, Placido, E-mail: ivan_rr1@hotmail.com [Benemerita Universidad Autonoma de Puebla, Fisicoquimica de Materiales ICUAP (Mexico)

    2011-01-01

    Dispersion is a quite important parameter in systems based on optical fiber, especially in pulsed emission lasers, where the temporal width is affected by such parameter. Therefore, it is necessary to consider the dispersion provoked by each component in the cavity. There are various experimental interferometric arrangements to evaluate this parameter. Generally, these systems modify the wavelength to obtain information about the n({lambda}) dependency, which is contained in the interferogram phase. However, this makes the system quite slow and it requires tunable and narrow bandwidth laser sources. In the present work, results obtained from an arrangement based on Mach-Zehnder interferometer where one of the arms is the optical fiber under study, while the reference one is air, are presented. In order to determine the n({lambda}) dependency, a wide spectrum light source was used in the wavelength range of interest. The phase information was evaluated from the interferometric signal measured by an optical spectrum analyzer.

  8. Improved pellet charge exchange measurements in Large Helical Device

    International Nuclear Information System (INIS)

    The pellet charge exchange technique (PCX), which is a combination of the compact neutral particle analyzer and an impurity pellet, is a unique method to observe the radial energetic particle distribution. There are not only charge exchange reactions between the hydrogen in the pellet and a proton, but also between the partially ionized carbon in the pellet and the proton. The neutralization factor from energetic ion to neutral particle could be deduced from the electron temperature and the electron density of the pellet cloud. The radial profiles of energetic particle distribution were measured and compared in various ion cyclotron resonance heating (ICH) plasmas. The energetic particle flux significantly increased at the resonance layer created by the ICH. PCX provides more precise information about the resonance layer than conventional neutral particle diagnostics. (author)

  9. Kelvin probe force microscopy for the nano scale characterization of chalcopyrite solar cell materials and devices

    International Nuclear Information System (INIS)

    Kelvin probe force microscopy allows to determine not only the surface topography as does atomic force microscopy, but in addition also delivers images of the surface work function on a nanometer scale. Operation in ultrahigh vacuum improves the lateral and energy resolution and allows to obtain absolute work function values. In this paper we will introduce the method and give examples for the application to solar cell materials and devices. We review examples where the surface of an oriented CuGaSe2 film showed distinct work function values for differently oriented facets of single grains, with differences as high as 250 meV, possibly affecting the power conversion efficiency of a solar cell. A cross-sectional study of a complete solar cell device based on the CuGaSe2 absorber material revealed the formation of an additional MoSex layer between the Mo back contact and the absorber. We will present results of measurements at individual grain boundaries of the absorber material. Furthermore, band bending effects at these grain boundaries are discussed and compared to results from transport studies

  10. Measuring cell identity in noisy biological systems

    OpenAIRE

    Birnbaum, Kenneth D; Kussell, Edo

    2011-01-01

    Global gene expression measurements are increasingly obtained as a function of cell type, spatial position within a tissue and other biologically meaningful coordinates. Such data should enable quantitative analysis of the cell-type specificity of gene expression, but such analyses can often be confounded by the presence of noise. We introduce a specificity measure Spec that quantifies the information in a gene's complete expression profile regarding any given cell type, and an uncertainty me...

  11. A single-shot rapid-mixing device for radiobiological studies with mammalian cells

    International Nuclear Information System (INIS)

    The rapid-mixing device is based on a syringe driven by a stepper motor and can inject up to 2 cm3 liquid in <100 ms. The radiation source, a 4MV Van de Graaff accelerator, provides an electron beam which is deflected from the beam dump on to the sample in two stages, providing a 10 ms radiation pulse. A digital delay circuit defines the interval between mixing and irradiation. The apparatus has been designed to study the kinetics of processes that occur over a time range extending from about 0.1 s to some minutes. It bridges the gap between the ranges available with conventional fast-mixing and those using standard X- or γ-irradiation methods. The time resolution of the technique has been examined by following the timecourse of radiosensitization by oxygen in mammalian cells. The timecourse of radioprotection of aerobic mammalian cells by dithiothreitol has been measured using the technique. (author)

  12. Rotational knee laxity: Reliability of a simple measurement device in vivo

    Directory of Open Access Journals (Sweden)

    Zantop Thore

    2008-03-01

    Full Text Available Abstract Background Double bundle ACL reconstruction has been demonstrated to decrease rotational knee laxity. However, there is no simple, commercially-available device to measure knee rotation. The investigators developed a simple, non-invasive device to measure knee rotation. In conjunction with a rigid boot to rotate the tibia and a force/moment sensor to allow precise determination of torque about the knee, a magnetic tracking system measures the axial rotation of the tibia with respect to the femur. This device has been shown to have acceptable levels of test re-test reliability to measure knee rotation in cadaveric knees. Methods The objective of this study was to determine reliability of the device in measuring knee rotation of human subjects. Specifically, the intra-tester reliability within a single testing session, test-retest reliability between two testing sessions, and inter-tester reliability were assessed for 11 male subjects with normal knees. Results The 95% confidence interval for rotation was less than 5° for intra-tester, test-retest, and inter-tester reliability, and the standard error of measurement for the differences between left and right knees was found to be less than 3°. Conclusion It was found that the knee rotation measurements obtained with this device have acceptable limits of reliability for clinical use and interpretation.

  13. Exploration about detection efficient of the device measuring radon in balloon method

    International Nuclear Information System (INIS)

    Background: Detection efficient is one of the important technical parameters in the device of measuring radon in balloon method. Its value would influence the veracity of the result. Purpose: This paper had explored a new method about calculating detection efficient of the device measuring radon in balloon method. Methods: The expression of detection efficient η has been deduced based on the principle of measuring radon and the new device which is IED-3000F developed by Chengdu University of Technology. Results: The detection efficient' experimental value has been measured. Conclusions: The result show that this theory used in calculating detection of balloon method for measurement of radon is quite feasible in the range of error. (authors)

  14. Measuring p53 Binding to Single DNA Molecules in a Nanofluidic Device

    Science.gov (United States)

    Whelsky, Amber; Gonzalez, Nicholas, Jr.; Gal, Susannah; Levy, Stephen

    2012-02-01

    Protein-DNA binding is central to several important cellular processes, for instance, the transfer of genetic information into proteins. The p53 protein plays a central role in regulating several major cell cycle pathways, in part by binding to well-characterized DNA sequences in the promoters of specific genes. Recent studies show that the most common mutation to the protein occurs in the region responsible for its binding to DNA. We have fabricated slit-like nanofluidic devices that allow us to trap and stretch single molecules of DNA containing a known recognition sequence of p53. We use fluorescent microscopy to observe the diffusion of a single p53 protein as it searches for its DNA recognition site. We measure the reaction rates of binding to selected DNA sequences as well as the one-dimensional, non-sequence specific diffusion of p53 along a stretched DNA molecule as a function of salt concentration. The mechanism of facilitated diffusion attempts to explain how proteins seem able to find their DNA target sequences much more quickly than would be expected from three-dimensional diffusion alone. We compare the observed search mechanism used by normal and mutated p53 from cancer cells to predictions based on this theory.

  15. Deformability and size-based cancer cell separation using an integrated microfluidic device.

    Science.gov (United States)

    Pang, Long; Shen, Shaofei; Ma, Chao; Ma, Tongtong; Zhang, Rui; Tian, Chang; Zhao, Lei; Liu, Wenming; Wang, Jinyi

    2015-11-01

    Cell sorting by filtration techniques offers a label-free approach for cell separation on the basis of size and deformability. However, filtration is always limited by the unpredictable variation of the filter hydrodynamic resistance due to cell accumulation and clogging in the microstructures. In this study, we present a new integrated microfluidic device for cell separation based on the cell size and deformability by combining the microstructure-constricted filtration and pneumatic microvalves. Using this device, the cell populations sorted by the microstructures can be easily released in real time for subsequent analysis. Moreover, the periodical sort and release of cells greatly avoided cell accumulation and clogging and improved the selectivity. Separation of cancer cells (MCF-7, MDA-MB-231 and MDA231-LM2) with different deformability showed that the mixture of the less flexible cells (MCF-7) and the flexible cells (MDA-MB-231 and MDA231-LM2) can be well separated with more than 75% purity. Moreover, the device can be used to separate cancer cells from the blood samples with more than 90% cell recovery and more than 80% purity. Compared with the current filtration methods, the device provides a new approach for cancer cell separation with high collection recovery and purity, and also, possesses practical potential to be applied as a sample preparation platform for fundamental studies and clinical applications. PMID:26366443

  16. The Architecture of Colloidal Quantum Dot Solar Cells: Materials to Devices

    KAUST Repository

    Kramer, Illan J.

    2014-01-08

    The materials chemistry of Colloidal Quantum Dot (CQDs) suspended in solution and processed into films has provided a foundation onto which useful photovoltaic devices can be built. These active materials offer the benefits of solution processing paired with the flexibility of adjustable bandgaps, tailored to suit a particular need. In parallel with these advances, pursuing device geometries that better leverage the available electronic properties of CQD films has borne fruit in further advancing CQD solar cell performance. For active materials such as CQD films where 1/α, where alpha is the absorption coefficient, is of the same order as the free carrier extraction length, external quantum efficiency (EQE) measurements have proved useful in profiling the effectiveness of each nanometer of device thickness at extracting photogenerated carriers. Because CQD films have the added complications of being made of variable-sized constituent material building blocks as well as being deposited from solution, the nature of charge transport through the films can also be size-dependent and matrix dependent.

  17. Measurement of cancellous bone strain during mechanical tests using a new extensometer device.

    Science.gov (United States)

    Boyd, S; Shrive, N; Wohl, G; Müller, R; Zernicke, R

    2001-07-01

    A device for measuring mid-substance strain in bone during uniaxial compression was developed with special attention to subsequent FE modelling. It is based on dual instrumented cantilever arms that measure the difference in tip-to-tip deflection. The so-called extensometer device was compared to two standard methods of measuring strain based on platen measurements. The extensometer device output was highly linear with tip deflection (r(2)>0.99), and contact of the devices with the specimen was optimized by using an axial distribution of three devices fixed in a free-floating jig. Deflection of the extensometer arms was accurate to 4.8 microm, and precision was between 2-5 microm. Tests included measuring rubber test specimens and cylindrical cancellous bone cores extracted from canine femoral condyles. A trend of decreasing apparent modulus with decreasing strain rate was evident with the extensometer technique. Correlation between the extensometer method and the other two methods was r(2)=0.55. The measure of mid-substance strain avoids non-linearities in the compression tests caused by early failure at the specimen ends, and the uniaxial testing conditions result in boundary conditions that are well suited for subsequent finite element analysis. PMID:11551817

  18. A new highly adaptable design of shear-flow device for orientation of macromolecules for Linear Dichroism (LD) measurement

    KAUST Repository

    Lundahl, P. Johan

    2011-01-01

    This article presents a new design of flow-orientation device for the study of bio-macromolecules, including DNA and protein complexes, as well as aggregates such as amyloid fibrils and liposome membranes, using Linear Dichroism (LD) spectroscopy. The design provides a number of technical advantages that should make the device inexpensive to manufacture, easier to use and more reliable than existing techniques. The degree of orientation achieved is of the same order of magnitude as that of the commonly used concentric cylinders Couette flow cell, however, since the device exploits a set of flat strain-free quartz plates, a number of problems associated with refraction and birefringence of light are eliminated, increasing the sensitivity and accuracy of measurement. The device provides similar shear rates to those of the Couette cell but is superior in that the shear rate is constant across the gap. Other major advantages of the design is the possibility to change parts and vary sample volume and path length easily and at a low cost. © 2011 The Royal Society of Chemistry.

  19. Cell separator for use in bipolar-stack energy storage devices

    Science.gov (United States)

    Mayer, Steven T.; Feikert, John H.; Kachmitter, James L.; Pekala, Richard W.

    1995-01-01

    An improved multi-cell electrochemical energy storage device, such as a battery, fuel cell, or double layer capacitor using a cell separator which allows cells to be stacked and interconnected with low electrical resistance and high reliability while maximizing packaging efficiency. By adding repeating cells, higher voltages can be obtained. The cell separator is formed by applying an organic adhesive on opposing surfaces of adjacent carbon electrodes or surfaces of aerogel electrodes of a pair of adjacent cells prior to or after pyrolysis thereof to form carbon aerogel electrodes. The cell separator is electronically conductive, but ionically isolating, preventing an electrolytic conduction path between adjacent cells in the stack.

  20. Adhesion and Interfacial Fracture: From Organic Light Emitting Devices and Photovoltaic Cells to Solar Lanterns for Developing Regions

    Science.gov (United States)

    Tong, Tiffany Michelle

    From that “ah-ha!” moment when a new technology is first conceived until the time that it reaches the hands of consumers, products undergo numerous iterations of research, development, testing, and redesign in order to create an end-product that is relevant, desirable, functional, and affordable. One crucial step, particularly for electronic devices, is a rigorous testing stage to ensure that a product will be able to withstand regular wear-and-tear. An understanding of how, when, and under what conditions a technology will fail is important in improving device performance and creating high quality products that consumers trust. Understanding that success is inherently tied to failure, this thesis focuses on studies of mechanical failure related to two types of electronic devices: solar cells and light emitting devices. By considering the interfaces that are relevant to the next generation of solar cells and light emitting devices that are built using organic conducting polymers, an atomic force microscopy test is introduced to characterize and rank the relative interfacial adhesion between layers at the nano-scale. These results have implications for material selection that can enhance device processing and performance. This method is then linked to fracture mechanics techniques that determine critical loading forces that induce separation and, hence, mechanical failure between layers of these devices. These results demonstrate the effect of nano-scale interactions on macro-scale behavior, and are particularly valuable in product testing as flexible electronics gain interest. Finally, a case study is conducted in Rural Kenya that measures the impact of commercially-available LED lanterns that are charged by solar panels on a community that is disconnected from the power grid. By demonstrating the value of these lanterns for the community, the role of device reliability and lifetime is examined in underscoring the critical need for proper device testing before

  1. Single-cell measurement of red blood cell oxygen affinity

    CERN Document Server

    Caprio, Di; Higgins, John M; Schonbrun, Ethan

    2015-01-01

    Oxygen is transported throughout the body by hemoglobin in red blood cells. While the oxygen affinity of blood is well understood and is routinely assessed in patients by pulse oximetry, variability at the single-cell level has not been previously measured. In contrast, single-cell measurements of red blood cell volume and hemoglobin concentration are taken millions of times per day by clinical hematology analyzers and are important factors in determining the health of the hematologic system. To better understand the variability and determinants of oxygen affinity on a cellular level, we have developed a system that quantifies the oxygen saturation, cell volume and hemoglobin concentration for individual red blood cells in high-throughput. We find that the variability in single-cell saturation peaks at an oxygen partial pressure of 2.5%, which corresponds to the maximum slope of the oxygen-hemoglobin dissociation curve. In addition, single-cell oxygen affinity is positively correlated with hemoglobin concentr...

  2. Frequency dependence on the accuracy of electrical impedance spectroscopy measurements in microfluidic devices

    International Nuclear Information System (INIS)

    This communication presents the dependence on frequency of the accuracy of electrical impedance spectroscopy (EIS) measurements in microfluidic devices. For this study, a very simple microfluidic device was used, with a hydrophilic microfluidic channel in which two parallel electrodes were patterned. Glass was the preferred substrate material for the fabrication of this microfluidic device, mainly due to its excellent dielectric properties even at relatively high frequencies. The testing was performed in air, and with DI water, ethanol and solutions of silica beads suspended in ethanol. The results show that the accuracy of the measurement increases with the frequency. The variation of the average of standard deviation error was between 13% at 10 kHz and less than 1% at 100 MHz. This clearly indicates that a high frequency range must be considered for further studies using electrical impedance spectroscopy in microfluidic devices. (brief communication)

  3. An industrial radiography exposure device based on measurement of transmitted gamma-ray intensity

    Science.gov (United States)

    Polee, C.; Chankow, N.; Srisatit, S.; Thong-Aram, D.

    2015-05-01

    In film radiography, underexposure and overexposure may happen particularly when lacking information of specimen material and hollowness. This paper describes a method and a device for determining exposure in industrial gamma-ray radiography based on quick measurement of transmitted gamma-ray intensity with a small detector. Application software was developed for Android mobile phone to remotely control the device and to display counting data via Bluetooth communication. Prior to film exposure, the device is placed behind a specimen to measure transmitted intensity which is inversely proportional to the exposure. Unlike in using the conventional exposure curve, correction factors for source decay, source-to- film distance, specimen thickness and kind of material are not needed. The developed technique and device make radiographic process economic, convenient and more reliable.

  4. The Measurement of Spectral Characteristics and Composition of Radiation in ATLAS with MEDIPIX2-USB Devices

    CERN Document Server

    Campbell, M.; Greiffenberg, D.; Heijne, E.; Holy, T.; Idárraga, J.; Jakubek, J.; Král, V.; Králík, M.; Lebel, C.; Leroy, C.; Llopart, X.; Lord, G.; Maneuski, D.; Ouellette, O.; Sochor, V.; Prospísil, S.; Suk, M; Tlustos, L.; Vykydal, Z.; Wilhelm, I.

    2008-01-01

    A network of devices to perform real-time measurements of the spectral characteristics and composition of radiation in the ATLAS detector and cavern during its operation is being built. This system of detectors will be a stand alone system fully capable of delivering real-time images of fluxes and spectral composition of different particle species including slow and fast neutrons. The devices are based on MEDIPIX2 pixel silicon detectors that will be operated via active USB cables and USB-Ethernet extenders through an Ethernet network by a PC located in the USA15 ATLAS control room. The installation of 14 devices inside ATLAS (detector and cavern) is in progress.

  5. Attenuation length measurements of liquid scintillator with LabVIEW and reliability evaluation of the device

    CERN Document Server

    Gao, L; Ding, YY; Zhou, L; Wen, LJ; Xie, YG; Wang, ZG; Cai, X; Sun, XL; Fang, J; Xue, Z; Zhang, AW; LÜ, QW; Sun, LJ; Ge, YS; Liu, YB; Niu, SL; Hu, T; Cao, J; LÜ, JG

    2013-01-01

    The attenuation length measuring device was constructed by using oscilloscope and LabVIEW for signal acquisition and processing. The performance of the device has been tested with a variety of ways, the test results show that the set-up has a good stability and high precision (sigma/mean reached 0.4 percent). Besides, the accuracy of the measurement system will decrease by about 17 percent if a filter is used. The attenuation length of gadolinium-loaded liquid scintillator (Gd-LS) was measured as 15.10 plus or minus 0.35 m where Gd-LS was heavily used in Daya Bay Neutrino Experiment. In addition, one method based on the Beer-Lambert law was proposed to investigate the reliability of the measurement device, the R-square reached 0.9995. Moreover, three purification methods for Linear Alkyl Benzene (LAB) production were compared in the experiment.

  6. A Methodology to Measure the Environmental Impact of ICT Operating Systems across Different Device Platforms

    Institute of Scientific and Technical Information of China (English)

    Daniel R. Williams; Yinshan Tang

    2015-01-01

    Abstract-A new methodology was created to measure the energy consumption and related green house gas (GHG) emissions of a computer operating system (OS) across different device platforms. The methodology involved the direct power measurement of devices under different activity states. In order to include all aspects of an OS, the methodology included measurements in various OS modes, whilst uniquely, also incorporating measurements when running an array of defined software activities, so as to include OS application management features. The methodology was demonstrated on a laptop and phone that could each run multiple OSs, results confirmed that OS can significantly impact the energy consumption of devices. In particular, the new versions of the Microsoft Windows OS were tested and highlighted significant differences between the OS versions on the same hardware. The developed methodology could enable a greater awareness of energy consumption, during both the software development and software marketing processes.

  7. Optofluidic Temperature and Pressure Measurements with Fiber Bragg Gratings Embedded in Microfluidic Devices

    CERN Document Server

    Cooksey, Gregory A

    2016-01-01

    The integration of photonic sensors into microfluidic devices provides opportunities for dynamic measurement of chemical and physical properties of fluids in very small volumes. We previously reported on the use of commercially available Fiber Bragg Gratings (FBGs) and on-chip silicon waveguides for temperature sensing. In this report, we demonstrate the integration of FBGs into easy-to-fabricate microfluidic devices and report on their sensitivity for temperature and pressure measurement in microliter volumes. These sensors present new routes to measurement in microfluidic applications such as small-volume calorimetry and microflow metrology.

  8. Cell mechanics measured with Atomic force microscopy

    International Nuclear Information System (INIS)

    Full text: In this contribution, I would like to present recent results about cell mechanics obtained with atomic force microscopy and its relation with basic soft matter science. We will present a novel way to obtain viscoelastic properties (Young modulus, relaxation time and viscosity) of breast cancer cells based on stress relaxation and creep measurements. Additionally we will show the influence of applied stress on red blood cell shape. The importance of such type of measurements on soft matter physics, cell biology, and biomedical science. (author)

  9. Design project of the device for measuring the radioactivity of wires

    International Nuclear Information System (INIS)

    This report includes the detailed design description and engineering drawings of the device and equipment for measuring the radioactivity of a wire. The wire is irradiated in the reactor core. The activity of the wire proportional to the neutron flux enables determining the neutron flux distribution. Activity is measured by GM counter

  10. The biased balance: Observation, formalism and interpretation of a dissymmetric measuring device

    OpenAIRE

    Le Menestrel, Marc

    2007-01-01

    This paper studies a balance whose unobservable fulcrum is not necessarily located at the middle of its two pans. It presents three different models, showing how this lack of symmetry modifies the observation, the formalism and the interpretation of such a biased measuring device. It argues that the biased balance can be an interesting source of inspiration for broadening the representational theory of measurement.

  11. Electrical tissue impedance spectroscopy : a novel device to measure esophageal mucosal integrity changes during endoscopy

    NARCIS (Netherlands)

    Weijenborg, P. W.; Rohof, W. O. A.; Akkermans, L. M. A.; Verheij, J.; Smout, A. J. P. M.; Bredenoord, A. J.

    2013-01-01

    Background Patients with gastroesophageal reflux disease (GERD) have impaired esophageal mucosal integrity. Measurement of the mucosal integrity is complex and time-consuming. Electrical tissue impedance spectroscopy (ETIS) is a device that measures impedance of tissue in vivo during endoscopy. In t

  12. Detail of photo 7903109 stack of superconducting cables in the modulus measuring device

    CERN Multimedia

    1979-01-01

    The picture shows an assembly of insulated superconducting cables of the type used in the Po dipole magnet inserted in the elastic modulus measuring device (photos 7903547X and 7903169) in order to measures its mechanical properties under azimuthal compression. See also 7903547X, 7903169, 8307552X.

  13. UNIVERSAL AUTO-CALIBRATION FOR A RAPID BATTERY IMPEDANCE SPECTRUM MEASUREMENT DEVICE

    Energy Technology Data Exchange (ETDEWEB)

    Jon P. Christophersen; John L. Morrison; William H. Morrison

    2014-03-01

    Electrochemical impedance spectroscopy has been shown to be a valuable tool for diagnostics and prognostics of energy storage devices such as batteries and ultra-capacitors. Although measurements have been typically confined to laboratory environments, rapid impedance spectrum measurement techniques have been developed for on-line, embedded applications as well. The prototype hardware for the rapid technique has been validated using lithium-ion batteries, but issues with calibration had also been identified. A new, universal automatic calibration technique was developed to address the identified issues while also enabling a more simplified approach. A single, broad-frequency range is used to calibrate the system and then scaled to the actual range and conditions used when measuring a device under test. The range used for calibration must be broad relative to the expected measurement conditions for the scaling to be successful. Validation studies were performed by comparing the universal calibration approach with data acquired from targeted calibration ranges based on the expected range of performance for the device under test. First, a mid-level shunt range was used for calibration and used to measure devices with lower and higher impedance. Next, a high excitation current level was used for calibration, followed by measurements using lower currents. Finally, calibration was performed over a wide frequency range and used to measure test articles with a lower set of frequencies. In all cases, the universal calibration approach compared very well with results acquired following a targeted calibration. Additionally, the shunts used for the automated calibration technique were successfully characterized such that the rapid impedance measurements compare very well with laboratory-scale measurements. These data indicate that the universal approach can be successfully used for onboard rapid impedance spectra measurements for a broad set of test devices and range of

  14. Noise trauma induced by a mousetrap--sound pressure level measurement of vole captive bolt devices.

    Science.gov (United States)

    Frank, Matthias; Napp, Matthias; Lange, Joern; Grossjohann, Rico; Ekkernkamp, Axel; Beule, Achim G

    2010-05-01

    While ballistic parameters of vole captive bolt devices have been reported, there is no investigation on their hazardous potential to cause noise trauma. The aim of this experimental study was to measure the sound pressure levels of vole captive bolt devices. Two different shooting devices were examined with a modular precision sound level meter on an outdoor firing range. Measurements were taken in a semi-circular configuration with measuring points 0 degrees in front of the muzzle, 90 degrees at right angle of the muzzle, and 180 degrees behind the shooting device. Distances between muzzle and microphone were 0.5, 1, 2, 10, and 20 m. Sound pressure levels exceeded 130 dB(C) at any measuring point within the 20-m area. Highest measurements (more than 172 dB[C]) were taken in the 0 degrees direction at the 0.5-m distance for both shooting devices proving the hazardous potential of these gadgets to cause noise trauma. PMID:20345785

  15. Reliability Through Life of Internal Protection Devices in Small-Cell ABSL Batteries

    Science.gov (United States)

    Neubauer, Jeremy; Ng, Ka Lok; Bennetti, Andrea; Pearson, Chris; Rao, gopal

    2007-01-01

    This viewgraph presentation reviews a reliability analysis of small cell protection batteries. The contents include: 1) The s-p Topology; 2) Cell Level Protection Devices; 3) Battery Level Fault Protection; 4) Large Cell Comparison; and 5) Battery Level Testing and Results.

  16. A device to improve the Schleger and Turner method for sweating rate measurements

    Science.gov (United States)

    Pereira, Alfredo Manuel Franco; Alves, Alexandre; Infante, Paulo; Titto, Evaldo A. L.; Baccari, Flávio; Almeida, J. A. Afonso

    2010-01-01

    The objective of this study was to test a device developed to improve the functionality, accuracy and precision of the original technique for sweating rate measurements proposed by Schleger and Turner [Schleger AV, Turner HG (1965) Aust J Agric Res 16:92-106]. A device was built for this purpose and tested against the original Schleger and Turner technique. Testing was performed by measuring sweating rates in an experiment involving six Mertolenga heifers subjected to four different thermal levels in a climatic chamber. The device exhibited no functional problems and the results obtained with its use were more consistent than with the Schleger and Turner technique. There was no difference in the reproducibility of the two techniques (same accuracy), but measurements performed with the new device had lower repeatability, corresponding to lower variability and, consequently, to higher precision. When utilizing this device, there is no need for physical contact between the operator and the animal to maintain the filter paper discs in position. This has important advantages: the animals stay quieter, and several animals can be evaluated simultaneously. This is a major advantage because it allows more measurements to be taken in a given period of time, increasing the precision of the observations and diminishing the error associated with temporal hiatus (e.g., the solar angle during field studies). The new device has higher functional versatility when taking measurements in large-scale studies (many animals) under field conditions. The results obtained in this study suggest that the technique using the device presented here could represent an advantageous alternative to the original technique described by Schleger and Turner.

  17. The cell-stretcher: A novel device for the mechanical stimulation of cell populations

    Science.gov (United States)

    Seriani, S.; Del Favero, G.; Mahaffey, J.; Marko, D.; Gallina, P.; Long, C. S.; Mestroni, L.; Sbaizero, O.

    2016-08-01

    Mechanical stimulation appears to be a critical modulator for many aspects of biology, both of living tissue and cells. The cell-stretcher, a novel device for the mechanical uniaxial stimulation of populations of cells, is described. The system is based on a variable stroke cam-lever-tappet mechanism which allows the delivery of cyclic stimuli with frequencies of up to 10 Hz and deformation between 1% and 20%. The kinematics is presented and a simulation of the dynamics of the system is shown, in order to compute the contact forces in the mechanism. The cells, following cultivation and preparation, are plated on an ad hoc polydimethylsiloxane membrane which is then loaded on the clamps of the cell-stretcher via force-adjustable magnetic couplings. In order to show the viability of the experimentation and biocompatibility of the cell-stretcher, a set of two in vitro tests were performed. Human epithelial carcinoma cell line A431 and Adult Mouse Ventricular Fibroblasts (AMVFs) from a dual reporter mouse were subject to 0.5 Hz, 24 h cyclic stretching at 15% strain, and to 48 h stimulation at 0.5 Hz and 15% strain, respectively. Visual analysis was performed on A431, showing definite morphological changes in the form of cellular extroflections in the direction of stimulation compared to an unstimulated control. A cytometric analysis was performed on the AMVF population. Results show a post-stimulation live-dead ratio deviance of less than 6% compared to control, which proves that the environment created by the cell-stretcher is suitable for in vitro experimentation.

  18. Investigation of bias radiation effect on PV cell measurement

    Science.gov (United States)

    Huang, Xuebo; Quan, Chenggen; Chan, Joanne; Ng, Patrick

    2013-06-01

    Photovoltaic (PV) cells are photo-electrical devices that convert light energy directly into electricity through the photovoltaic effect. PV cell assemblies are used to make solar modules employed in a variety of ways ranging from space applications to domestic energy consumption. Characterisation and performance testing of PV cells are critical to the development of PV technologies and growth of the solar industry. As new solar products are being developed, its energy conversion efficiency and other critical parameters must be accurately measured and tested against globally recognised metrological standards. The differential spectral responsivity (DSR) measurement is one of the primary methods for calibrating reference PV cells. This is done by calculating its spectral responsivities through measuring the AC short-circuit current produced by a PV cell under a modulated monochromatic radiation and different levels of steady-state broadband bias light radiation. It is observed that different types of bias light source will produce different signal-to-noise levels and significantly influence measurement accuracy. This paper aims to investigate the noise sources caused by different types of bias light sources (e.g. xenon arc and tungsten-halogen lamps) and the relevant measurement uncertainties so as to propose a guideline for selection of bias light source which can improve the signal-to-noise level and measurement uncertainty. The DSRs of the PV cells are measured using a commercial DSR measurement system under different levels of bias radiation from 0 to 1 kWm-2. The data analysis and uncertainty evaluation are presented in this paper using experimental data and mathematical tools.

  19. Non-Destructive Detection and Separation of Radiation Damaged Cells in Miniaturized, Inexpensive Device Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Our objective is to develop and demonstrate a novel microfluidic device for non-destructive identification, sorting and counting of radiation damaged cells. A major...

  20. Measurement of inner and/or outer profiles of pipes using ring beam devices

    Science.gov (United States)

    Wakayama, T.; Yoshizawa, T.

    2009-11-01

    Inner profile measurement is an important matter in such fields as medicine, dentistry and anthropology as well as mechanical engineering and industry. Here we propose a measurement method for inner diameter of pipes and/or holes. The key device in this technique is a ring beam device which consists of a conical mirror and a laser diode. And the fundamental principle is based on optical sectioning without any contact probe. The optically sectioned profile of an inner wall of a pipe-like object is analyzed to give the inner profile in addition to the inner diameter. This optical instrument with a simple and small configuration is now under development for practical uses. In the hitherto-tried experimental works, the availability of this instrument has been highly evaluated and usability for practical applications is expected, especially, for measurement and inspection of mechanical components and elements besides pipes. This ring beam device consisting of a conical mirror and a LD is assembled to form a disklike light beam sheet. We show measurement result of pipes and holes, and, at the same time, report a compact inner profile measuring instrument. Both the ring beam device and a miniaturized CCD camera are fabricated in a glass tube. Availability of this instrument is shown by measuring the inner profiles of various pipes. In response to this trial, there appeared a strong request that not only the internal but external profiles should be measured simultaneously. Therefore we propose an improved method for measuring the external profile in addition to the internal profile. In our arrangement, one pair of concaved conical mirrors is used for the external profile measurement. In combination with the inner profile measurement technique, simultaneous measurement of the inner and outer profiles becomes attainable. A measurement result on a bevel gear shows availability of newly proposed principle. Now we are aiming to realize simultaneous measurement of the internal

  1. Measuring Soil Moisture using the Signal Strength of Buried Bluetooth Devices.

    Science.gov (United States)

    Hut, R.; Campbell, C. S.

    2015-12-01

    A low power bluetooth Low Energy (BLE) device is burried 20cm into the soil and a smartphone is placed on top of the soil to test if bluetooth signal strength can be related to soil moisture. The smartphone continuesly records and stores bluetooth signal strength of the device. The soil is artifcially wetted and drained. Results show a relation between BLE signal strength and soil moisture that could be used to measure soil moisture using these off-the-shelf consumer electronics. This opens the possibily to develop sensors that can be buried into the soil, possibly below the plow-line. These sensors can measure local parameters such as electric conductivity, ph, pressure, etc. Readings would be uploaded to a device on the surface using BLE. The signal strength of this BLE would be an (additional) measurement of soil moisture.

  2. Sensor Measurement Strategies for Monitoring Offshore Wind and Wave Energy Devices

    Science.gov (United States)

    O'Donnell, Deirdre; Srbinovsky, Bruno; Murphy, Jimmy; Popovici, Emanuel; Pakrashi, Vikram

    2015-07-01

    While the potential of offshore wind and wave energy devices is well established and accepted, operations and maintenance issues are still not very well researched or understood. In this regard, scaled model testing has gained popularity over time for such devices at various technological readiness levels. The dynamic response of these devices are typically measured by different instruments during such scaled tests but agreed sensor choice, measurement and placement guidelines are still not in place. This paper compared the dynamic responses of some of these sensors from a scaled ocean wave testing to highlight the importance of sensor measurement strategies. The possibility of using multiple, cheaper sensors of seemingly inferior performance as opposed to the deployment of a small number of expensive and accurate sensors are also explored. An energy aware adaptive sampling theory is applied to highlight the possibility of more efficient computing when large volumes of data are available from the tested structures. Efficient sensor measurement strategies are expected to have a positive impact on the development of an device at different technological readiness levels while it is expected to be helpful in reducing operation and maintenance costs if such an approach is considered for the devices when they are in operation.

  3. Electrical Characterization of Organic Devices and Solar Cells by Impedance Spectroscopy

    OpenAIRE

    Burtone, Lorenzo

    2014-01-01

    In this work, the capacitive response of organic electronic devices is analysed. Particular attention is given to small-molecule organic solar cells, with the purpose of deriving an equivalent circuit for the small-signal response of these devices. The different components characterising the solar cells electrical response are individuated and discussed and a specific physical meaning is associated with each element of the equivalent circuit. In the experimental section, the capacitive e...

  4. Centrifugal Filter Device for Detection of Rare Cells With Immuno-Binding.

    Science.gov (United States)

    Chen, Chih-Chung; Chen, Yu-An; Yao, Da-Jeng

    2015-12-01

    Many investigations have shown circulating tumor cells (CTCs) to serve as a significant biomarker of cancer progression and for cancer treatment. Multiple blood samples detection of CTCs during a course of treatment might facilitate a choice by a medical doctor of an effective drug and a treatment for particular patients. A simple and cost-effective method to identify the trend of decreasing CTCs during a treatment with various therapies is in great demand. A novel multilayer, concentric filter device combined with an immune-binding method enables the enrichment and detection of rare cells in a mass cell population with a separation based on size. Such separation implemented with a filter is among the most efficient, simple and inexpensive methods to isolate cells, but its main disadvantages are clogging, deformation of cells, and a requirement of a significant difference of size between targeted rare cells and normal cells. We designed a concentric filter device and an immune-binding method to create a significant size difference of target cells, and increased the efficiency of separation to identify rare cells with a simple miniature centrifuge in the laboratory. The enrichment of target rare cells from a mass cell population and the detection were demonstrated on mixing targeted MCF-7 blast cancer cells and Jurkat blood cells in ratio 1:1 000 000. The device is prospectively applicable for the detection of circulating tumor cells in a clinical application. PMID:26452287

  5. Design and Development of Automatic Temperature Measurement Device Based on Can Bus Technology

    OpenAIRE

    Xin Lu; Yanhuang Zhou; Jincao Chen

    2013-01-01

    An automatic online temperature measurement device on the Modular Artillery Charge System (MACS) is designed and developed, based on Controller Area Network (CAN) bus technology in this study. For measuring automatically the temperature of the modular charge, a non-contact measurement method is proposed. The primary idea of this method is to obtain the real-time value of the modular charge temperature through solving the unsteady heat transfer equations describing the variation in the modular...

  6. Development of a puncture electronic device for electrical conductivity measurements throughout meat salting

    OpenAIRE

    García Breijo, Eduardo; Barat Baviera, José Manuel; Torres, Olga; Gil Sanchez, Luis; Ibáñez Civera, Javier; Alcañiz, Miguel; Masot, Rafael; Fraile Muñoz, Rubén

    2008-01-01

    Conductivity measurements of food systems are of high interest because they are related with food characteristics such as free water and salt content. Nevertheless, as far as now no devices have been developed for punctual conductivity measurements inside solid foods. The aim of this work was to develop a conductimeter which allows obtaining punctual measurements in different locations of solid foods. The sensor consists of a coaxial needle while an electrical sign controlled by microcontroll...

  7. Feasibility of an in situ measurement device for bubble size and distribution

    OpenAIRE

    Junker, Beth; Maciejak, Walter; Darnell, Branson; Lester, Michael; Pollack, Michael

    2007-01-01

    The feasibility of in situ measurement device for bubble size and distribution was explored. A novel in situ probe measurement system, the EnviroCam™, was developed. Where possible, this probe incorporated strengths, and minimized weaknesses of historical and currently available real-time measurement methods for bubbles. The system was based on a digital, high-speed, high resolution, modular camera system, attached to a stainless steel shroud, compatible with standard Ingold ports on fermente...

  8. A Cell Lysis and Protein Purification - Single Molecule Assay Devices for Evaluation of Genetically Engineered Proteins

    Science.gov (United States)

    Nakyama, Tetsuya; Tabata, Kazuhito; Noji, Hiroyuki; Yokokawa, Ryuji

    We have developed two devices applicable to evaluate genetically engineered proteins in single molecule assay: on-chip cell lysis device, and protein purification - assay device. A motor protein, F1-ATPase expressed in E.coli, was focused in this report as a target protein. Cell lysis was simply performed by applying pulse voltage between Au electrodes patterned by photolithography, and its efficiency was determined by absorptiometry. The subsequent processes, purification and assay of extracted proteins, were demonstrated in order to detect F1-ATPase and to evaluate its activity. The specific bonding between his-tag in F1-ATPase and Ni-NTA coated on a glass surface was utilized for the purification process. After immobilization of F1-ATPase, avidin-coated microspheres and adenosine tri-phosphate (ATP) solution were infused sequentially to assay the protein. Microsphere rotation was realized by activity of F1-ATPase corresponding to ATP hydrolysis. Results show that the cell lysis device, at the optimum condition, extracts enough amount of protein for single molecule assay. Once cell lysate was injected to the purification - assay device, proteins were diffused in the lateral direction in a Y-shape microchannel. The gradient of protein concentratioin provides an optimal concentration for the assay i.e. the highest density of rotating beads. Density of rotating beads is also affected by the initial concentration of protein injected to the device. The optimum concentration was achieved by our cell lysis device not by the conventional method by ultrasonic wave. Rotation speed was analyzed for several microspheres assayed in the purification - assay device, and the results were compatible to that of conventional assay in which F1-ATPase was purified in bulk scale. In conclusion, we have demonstrated on-chip cell lysis and assay appropriate for the sequential analysis without any pretreatment. On-chip devices replacing conventional bioanalytical methods will be

  9. A microfluidic device for epigenomic profiling using 100 cells

    OpenAIRE

    Cao, Zhenning; Chen, Changya; He, Bing; Tan, Kai; Lu, Chang

    2015-01-01

    The sensitivity of chromatin immunoprecipitation (ChIP) assays poses a major obstacle for epigenomic studies of low-abundance cells. Here we present a microfluidics-based ChIP-Seq protocol using as few as 100 cells via drastically improved collection of high-quality ChIP-enriched DNA. Using this technology, we uncovered many novel enhancers and super enhancers in hematopoietic stem and progenitor cells from mouse fetal liver, suggesting that enhancer activity is highly dynamic during early he...

  10. An Industrial Radipgraphy Exposure Device Based on Measurement of Transmitted Gamma-Ray Intensity

    International Nuclear Information System (INIS)

    In film radiography, underexposure and overexposure may happen particularly when lacking knowledge of specimen material and hollowness. This paper describes a method and a device for determining exposure in industrial gamma-ray radiography based on quick measurement of transmitted gamma-ray intensity with a D3372 Hamamatsu small GM tube. Application software is developed for Android mobile phone to remotely control the device and to display the counting data via Bluetooth. Prior to placing film, the device is placed behind the specimen to be radiographed to determine the exposure time from the transmitted intensity which is independent on source activity, source-to-film distance, specimen thickness and kind of material. The developed technique and device make radiographic process economic, convenient and more reliable.

  11. Characterization of thermoelectric devices by laser induced Seebeck electromotive force (LIS-EMF) measurement

    Energy Technology Data Exchange (ETDEWEB)

    Lopez, Luis-David Patino [Universite de Bordeaux 1, Centre de Physique Moleculaire Optique et Hertzienne, 351, cours de la liberation, 33405 Talence (France); Dilhaire, Stefan [Universite de Bordeaux 1, Centre de Physique Moleculaire Optique et Hertzienne, 351, cours de la liberation, 33405 Talence (France); Grauby, Stephane [Universite de Bordeaux 1, Centre de Physique Moleculaire Optique et Hertzienne, 351, cours de la liberation, 33405 Talence (France); Salhi, M Amine [Universite de Bordeaux 1, Centre de Physique Moleculaire Optique et Hertzienne, 351, cours de la liberation, 33405 Talence (France); Ezzahri, Younes [Universite de Bordeaux 1, Centre de Physique Moleculaire Optique et Hertzienne, 351, cours de la liberation, 33405 Talence (France); Claeys, Wilfrid [Universite de Bordeaux 1, Centre de Physique Moleculaire Optique et Hertzienne, 351, cours de la liberation, 33405 Talence (France); Batsale, Jean-Christophe [Laboratoire TREFLE, Esplanade des Arts et Metiers, 33405 Talence Cedex (France)

    2005-05-21

    An in-depth study related to a new method of characterizing properties in thermoelectrics is proposed in this paper. This technique is appropriate for single or multi-layered thermoelectric devices. A modulated laser beam is used as a heater in order to generate a Seebeck electromotive force (EMF). The laser beam, line shaped, can be focused at any location along the sample surface, allowing spatially resolved measurements. Seebeck EMF measurements, associated with a versatile model based on the thermal quadrupoles method, allow determination of the sample Seebeck EMF profile and identifying of the sample thermal contact resistances, and should be useful for identification of devices and material thermoelectric properties.

  12. Characterization of thermoelectric devices by laser induced Seebeck electromotive force (LIS-EMF) measurement

    Science.gov (United States)

    Patiño Lopez, Luis-David; Dilhaire, Stefan; Grauby, Stéphane; Amine Salhi, M.; Ezzahri, Younès; Claeys, Wilfrid; Batsale, Jean-Christophe

    2005-05-01

    An in-depth study related to a new method of characterizing properties in thermoelectrics is proposed in this paper. This technique is appropriate for single or multi-layered thermoelectric devices. A modulated laser beam is used as a heater in order to generate a Seebeck electromotive force (EMF). The laser beam, line shaped, can be focused at any location along the sample surface, allowing spatially resolved measurements. Seebeck EMF measurements, associated with a versatile model based on the thermal quadrupoles method, allow determination of the sample Seebeck EMF profile and identifying of the sample thermal contact resistances, and should be useful for identification of devices and material thermoelectric properties.

  13. Characterization of thermoelectric devices by laser induced Seebeck electromotive force (LIS-EMF) measurement

    International Nuclear Information System (INIS)

    An in-depth study related to a new method of characterizing properties in thermoelectrics is proposed in this paper. This technique is appropriate for single or multi-layered thermoelectric devices. A modulated laser beam is used as a heater in order to generate a Seebeck electromotive force (EMF). The laser beam, line shaped, can be focused at any location along the sample surface, allowing spatially resolved measurements. Seebeck EMF measurements, associated with a versatile model based on the thermal quadrupoles method, allow determination of the sample Seebeck EMF profile and identifying of the sample thermal contact resistances, and should be useful for identification of devices and material thermoelectric properties

  14. Organic solar cells theory, experiment, and device simulation

    CERN Document Server

    Tress, Wolfgang

    2014-01-01

    This book covers in a textbook-like fashion the basics or organic solar cells, addressing the limits of photovoltaic energy conversion and giving a well-illustrated introduction to molecular electronics with focus on the working principle and characterization of organic solar cells. Further chapters based on the author's dissertation focus on the electrical processes in organic solar cells by presenting a detailed drift-diffusion approach to describe exciton separation and charge-carrier transport and extraction. The results, although elaborated on small-molecule solar cells and with focus on

  15. Cell force measurements in 3D microfabricated environments based on compliant cantilevers.

    Science.gov (United States)

    Marelli, Mattia; Gadhari, Neha; Boero, Giovanni; Chiquet, Matthias; Brugger, Jürgen

    2014-01-21

    We report the fabrication, functionalization and testing of microdevices for cell culture and cell traction force measurements in three-dimensions (3D). The devices are composed of bent cantilevers patterned with cell-adhesive spots not lying on the same plane, and thus suspending cells in 3D. The cantilevers are soft enough to undergo micrometric deflections when cells pull on them, allowing cell forces to be measured by means of optical microscopy. Since individual cantilevers are mechanically independent of each other, cell traction forces are determined directly from cantilever deflections. This proves the potential of these new devices as a tool for the quantification of cell mechanics in a system with well-defined 3D geometry and mechanical properties. PMID:24217771

  16. A Two-Stage Microfluidic Device for the Isolation and Capture of Circulating Tumor Cells

    Science.gov (United States)

    Cook, Andrew; Belsare, Sayali; Giorgio, Todd; Mu, Richard

    2014-11-01

    Analysis of circulating tumor cells (CTCs) can be critical for studying how tumors grow and metastasize, in addition to personalizing treatment for cancer patients. CTCs are rare events in blood, making it difficult to remove CTCs from the blood stream. Two microfluidic devices have been developed to separate CTCs from blood. The first is a double spiral device that focuses cells into streams, the positions of which are determined by cell diameter. The second device uses ligand-coated magnetic nanoparticles that selectively attach to CTCs. The nanoparticles then pull CTCs out of solution using a magnetic field. These two devices will be combined into a single 2-stage microfluidic device that will capture CTCs more efficiently than either device on its own. The first stage depletes the number of blood cells in the sample by size-based separation. The second stage will magnetically remove CTCs from solution for study and culturing. Thus far, size-based separation has been achieved. Research will also focus on understanding the equations that govern fluid dynamics and magnetic fields in order to determine how the manipulation of microfluidic parameters, such as dimensions and flow rate, will affect integration and optimization of the 2-stage device. NSF-CREST: Center for Physics and Chemistry of Materials. HRD-0420516; Department of Defense, Peer Reviewed Medical Research Program Award W81XWH-13-1-0397.

  17. Quantitative Determination of Luminescent Coupling in Multijunction Solar Cells from Spectral Photovoltage Measurements

    Science.gov (United States)

    Fuertes Marrón, D.; Barrigón, E.; Ochoa, M.; Artacho, I.

    2016-07-01

    We present a simple method to quantify the magnitude of luminescent coupling (LC) between stacked subcells in multijunction photovoltaic devices. The effect of luminescence produced at high-band-gap subcells on underlying low-gap units within the same device can be directly accessed as a measurable open-circuit voltage difference by comparing two photovoltage spectra. Additionally, our study unambiguously identifies LC as the modulation mechanism across multijunction solar cells generating a response from buried subcells in photoreflectance measurements.

  18. Automatic measuring device based on the DRG 2-01 dosemeter

    International Nuclear Information System (INIS)

    A facility developed on the base of a commercial dosimetric device providing essential increase in charge determination accuracy for sensitive ranges and automation of the radiation field dosimetric characteristics measurement process is described. Improvement of the facility performances is attained by introducing an additional external trigger unit delay circuit unit which assure control pulse delay during 3-10 s. The whole facility control and exact time counting are made by a recounting device. A digital voltmeter the information from which is printed in a unit of automatic printing is included for increasing the accuracy of measurements. The given facility has been used for measuring charges induced by pulsed X radiation in ionization converters. According to the measurement results the facility gives an opportunity to reduce mean square error of X and #betta# radiation exposure dose measurement in 15 times

  19. Leakage detection device for storage vessel in cell

    International Nuclear Information System (INIS)

    High level liquid wastes of a nuclear power plant are concentrated, and then stored in a high level concentrated liquid waste storage vessel disposed in cells surrounded by shielding walls. Two spaces, in communication with each other, not undergoing influence of radioactivity in the cells by covering them with shielding members are formed to the inside and the outside of the cell while sandwiching a shielding wall. A sampling pipeline on the exit side of an air lift pump for sending drain from a dripping tray to a sampling facility is passed through the space inside the cell. A γ-ray detector is disposed as a radiation detector to the space outside the cell for detecting radioactivity concentration in the sampling pipeline. A collimator is disposed to a portion passing through a shielding wall. The result of detection of the γ-ray detector is displayed to the place where the sampling facility is disposed and a control chamber. (I.N.)

  20. Test-retest variability in structural parameters measured with glaucoma imaging devices.

    Science.gov (United States)

    Araie, Makoto

    2013-01-01

    In addition to classical stereo-disc photography, various glaucoma imaging devices were developed in the last two decades to quantitatively measure and record glaucoma-related structural parameters of the eye. In determining whether or not the glaucomatous damage progressed from baseline and in estimating the number of test results' optimal frequency needed to confirm disease progression, information relating to the test-retest variability of measurement results provided by each imaging device is indispensable. Such information enables the clinician to apply these devices in practice. The test-retest variability of a system is usually estimated using the Bland-Altman analysis and by calculating the coefficient of variation (CV), intraclass correlation coefficient (ICC), and minimum detectable changes (MDC). The reported CV, ICC, and MDC values for glaucoma-related structural parameter measurement results of stereo-disc photographs, confocal scanning laser ophthalmoscopes, scanning laser polarimeters, time-domain optical coherence tomography (OCT), spectral-domain OCT (SD-OCT), anterior-segment OCT, and ultrasound biomicroscope are systematically reviewed in this manuscript, which will enable the clinician to interpret measurement results provided by each glaucoma imaging devices and thus be useful in practice. Although SD-OCT systems may be currently prevailing because of the volume of information provided and the relatively better test-retest variability, these systems need improvement in their test-retest variability measurement capabilities. PMID:23138681

  1. Development of microfluidic-based cell collection devices for in vitro and in vivo use

    Science.gov (United States)

    Butt, Logan; Entenberg, Dave; Hemachandra, L. P. Madhubhani; Strohmayer, Matthew; Keely, Patricia; Aguirre-Ghiso, Julio; Condeelis, John S.; Castracane, James

    2016-03-01

    The NANIVID - or Nano Intravital Device - is an implantable delivery tool designed to locally affect the tumor microenvironment in vivo. This technology is being redesigned and validated as a cell collection tool for the study of metastatic cancer cells. A methodology has been developed to facilitate this transition, consisting of microfluidic analysis of the device microchannels and a series of cell-related collection experiments building up to in vivo collection. Single-chamber designs were first used to qualitatively demonstrate the feasibility of cell collection ex vivo. This was followed by the development and implementation of devices containing a second, negative-control chamber for quantitative analysis. This work sets the foundation for in vivo cancer cell migration studies utilizing the NANIVID.

  2. Measurement of mean arterial pressure: comparison of the Vasotrac monitor with the finger differential oscillometric device.

    Science.gov (United States)

    Jagomägi, K; Raamat, R; Talts, J; Ragun, U; Tähepõld, P

    2010-01-01

    The Vasotrac monitor provides non-invasive near-continuous blood pressure monitoring and is designed to be an alternative to direct intra-arterial blood pressure (BP) measurement. As compared to radial artery invasive BP and upper arm non-invasive BP, Vasotrac readings have been found to have a good agreement with them. However, discrepancies have been reported when rapid changes in BP exist. In the present study we compared BP measured by the Vasotrac monitor on the radial artery with that recorded on the finger arteries by the differential oscillometric device allowing measurement on the beat-to-beat basis. Comparisons were performed on the mean arterial pressure (MAP) level. Special attention was paid to the signal conditioning before comparison of pressures of different temporal resolution. Altogether 383 paired MAP measurements were made in 14 healthy subjects. Based on all 383 paired measurements, the MAP values measured at the radial artery at rest were 4.8+/-6.0 mm Hg higher than those measured on fingers. The observed difference between the Vasotrac and differential oscillometric device can be explained by different measurement sites. This result is consistent with previous investigations, and the Vasotrac monitor can be considered to adequately track relatively rapid MAP changes on the radial artery. Attention should be paid to a proper signal conditioning before comparison of results obtained by different devices. PMID:20406039

  3. Non-Contact Stiffness Measurement of a Suspended Single Walled Carbon Nanotube Device

    Science.gov (United States)

    Zheng, Yun; Su, Chanmin; Getty, Stephanie

    2010-01-01

    A new nanoscale electric field sensor was developed for studying triboelectric charging in terrestrial and Martian dust devils. This sensor is capable to measure the large electric fields for large dust devils without saturation. However, to quantify the electric charges and the field strength it is critical to calibrate the mechanical stiffness of the sensor devices. We performed a technical feasibility study of the Nano E-field Sensor stiffness by a non-contact stiffness measurement method. The measurement is based on laser Doppler vibrometer measurement of the thermal noise due to energy flunctuations in the devices. The experiment method provides a novel approach to acquire data that is essential in analyzing the quantitative performance of the E-field Nano Sensor. To carry out the non-contact stiffness measurement, we fabricated a new Single-Walled Carbon Nanotube (SWCNT) E-field sensor with different SWCNTs suspension conditions. The power spectra of the thermal induced displacement in the nano E-field sensor were measured at the accuracy of picometer. The power spectra were then used to derive the mechanical stiffness of the sensors. Effect of suspension conditions on stiffness and sensor sensitivty was discussed. After combined deformation and resistivity measurement, we can compare with our laboratory testing and field testing results. This new non-contact measurement technology can also help to explore to other nano and MEMS devices in the future.

  4. Performance of miniaturized direct methanol fuel cell (DMFC) devices using micropump for fuel delivery

    Science.gov (United States)

    Zhang, Tao; Wang, Qing-Ming

    A fuel cell is a device that can convert chemical energy into electricity directly. Among various types of fuel cells, both polymer electrolyte membrane fuel cells (PEMFCs) and direct methanol fuel cells (DMFCs) can work at low temperature (mini pumps, the size of the piezoelectric micropump is much smaller and the energy consumption is much lower. Thus, it is very viable and effective to use a piezoelectric valveless micropump for fuel delivery in miniaturized DMFC power systems.

  5. Mammosphere culture of cancer stem cells in a microfluidic device

    Science.gov (United States)

    Saadin, Katayoon; White, Ian M.

    2012-03-01

    It is known that tumor-initiating cells with stem-like properties will form spherical colonies - termed mammospheres - when cultured in serum-free media on low-attachment substrates. Currently this assay is performed in commercially available 96-well trays with low-attachment surfaces. Here we report a novel microsystem that features on-chip mammosphere culture on low attachment surfaces. We have cultured mammospheres in this microsystem from well-studied human breast cancer cell lines. To enable the long-term culture of these unattached cells, we have integrated diffusion-based delivery columns that provide zero-convection delivery of reagents, such as fresh media, staining agents, or drugs. The multi-layer system consists of parallel cell-culture chambers on top of a low-attachment surface, connected vertically with a microfluidic reagent delivery layer. This design incorporates a reagent reservoir, which is necessary to reduce evaporation from the cell culture micro-chambers. The development of this microsystem will lead to the integration of mammosphere culture with other microfluidic functions, including circulating tumor cell recovery and high throughput drug screening. This will enable the cancer research community to achieve a much greater understanding of these tumor initiating cancer stem cells.

  6. Measurement of Underwater Operational Noise Emitted by Wave and Tidal Stream Energy Devices.

    Science.gov (United States)

    Lepper, Paul A; Robinson, Stephen P

    2016-01-01

    The increasing international growth in the development of marine and freshwater wave and tidal energy harvesting systems has been followed by a growing requirement to understand any associated underwater impact. Radiated noise generated during operation is dependent on the device's physical properties, the sound-propagation environment, and the device's operational state. Physical properties may include size, distribution in the water column, and mechanics/hydrodynamics. The sound-propagation environment may be influenced by water depth, bathymetry, sediment type, and water column acoustic properties, and operational state may be influenced by tidal cycle and wave height among others This paper discusses some of the challenges for measurement of noise characteristics from these devices as well as a case study of the measurement of radiated noise from a full-scale wave energy converter. PMID:26611011

  7. Measuring the metastatic potential of cancer cells

    Science.gov (United States)

    Morrison, Dennis R.; Gratzner, Howard; Atassi, M. Z.

    1993-01-01

    Cancer cells must secrete proteolytic enzymes to invade adjacent tissues and migrate to a new metastatic site. Urokinase (uPA) is a key enzyme related to metastasis in cancers of the lung, colon, gastric, uterine, breast, brain, and malignant melanoma. A NASA technology utilization project has combined fluorescence microscopy, image analysis, and flow cytometry, using fluorescent dyes, and urokinase-specific antibodies to measure uPA and abnormal DNA levels (related to cancer cell proliferation) inside the cancer cells. The project is focused on developing quantitative measurements to determine if a patient's tumor cells are actively metastasizing. If a significant number of tumor cells contain large amounts of uPA (esp. membrane-bound) then the post-surgical chemotherapy or radiotherapy can be targeted for metastatic cells that have already left the primary tumor. These analytical methods have been applied to a retrospective study of biopsy tissues from 150 node negative, stage 1 breast cancer patients. Cytopathology and image analysis has shown that uPA is present in high levels in many breast cancer cells, but not found in normal breast. Significant amounts of uPA also have been measured in glioma cell lines cultured from brain tumors. Commercial applications include new diagnostic tests for metastatic cells, in different cancers, which are being developed with a company that provides a medical testing service using flow cytometry for DNA analysis and hormone receptors on tumor cells from patient biopsies. This research also may provide the basis for developing a new 'magic bullet' treatment against metastasis using chemotherapeutic drugs or radioisotopes attached to urokinase-specific monoclonal antibodies that will only bind to metastatic cells.

  8. Comparison of Chip Inlet Geometry in Microfluidic Devices for Cell Studies.

    Science.gov (United States)

    Sun, Yung-Shin

    2016-01-01

    Micro-fabricated devices integrated with fluidic components provide an in vitro platform for cell studies best mimicking the in vivo micro-environment. These devices are capable of creating precise and controllable surroundings of pH value, temperature, salt concentration, and other physical or chemical stimuli. Various cell studies such as chemotaxis and electrotaxis can be performed by using such devices. Moreover, microfluidic chips are designed and fabricated for applications in cell separations such as circulating tumor cell (CTC) chips. Usually, there are two most commonly used inlets in connecting the microfluidic chip to sample/reagent loading tubes: the vertical (top-loading) inlet and the parallel (in-line) inlet. Designing this macro-to-micro interface is believed to play an important role in device performance. In this study, by using the commercial COMSOL Multiphysics software, we compared the cell capture behavior in microfluidic devices with different inlet types and sample flow velocities. Three different inlets were constructed: the vertical inlet, the parallel inlet, and the vertically parallel inlet. We investigated the velocity field, the flow streamline, the cell capture rate, and the laminar shear stress in these inlets. It was concluded that the inlet should be designed depending on the experimental purpose, i.e., one wants to maximize or minimize cell capture. Also, although increasing the flow velocity could reduce cell sedimentation, too high shear stresses are thought harmful to cells. Our findings indicate that the inlet design and flow velocity are crucial and should be well considered in fabricating microfluidic devices for cell studies. PMID:27314318

  9. Comparison of Chip Inlet Geometry in Microfluidic Devices for Cell Studies

    Directory of Open Access Journals (Sweden)

    Yung-Shin Sun

    2016-06-01

    Full Text Available Micro-fabricated devices integrated with fluidic components provide an in vitro platform for cell studies best mimicking the in vivo micro-environment. These devices are capable of creating precise and controllable surroundings of pH value, temperature, salt concentration, and other physical or chemical stimuli. Various cell studies such as chemotaxis and electrotaxis can be performed by using such devices. Moreover, microfluidic chips are designed and fabricated for applications in cell separations such as circulating tumor cell (CTC chips. Usually, there are two most commonly used inlets in connecting the microfluidic chip to sample/reagent loading tubes: the vertical (top-loading inlet and the parallel (in-line inlet. Designing this macro-to-micro interface is believed to play an important role in device performance. In this study, by using the commercial COMSOL Multiphysics software, we compared the cell capture behavior in microfluidic devices with different inlet types and sample flow velocities. Three different inlets were constructed: the vertical inlet, the parallel inlet, and the vertically parallel inlet. We investigated the velocity field, the flow streamline, the cell capture rate, and the laminar shear stress in these inlets. It was concluded that the inlet should be designed depending on the experimental purpose, i.e., one wants to maximize or minimize cell capture. Also, although increasing the flow velocity could reduce cell sedimentation, too high shear stresses are thought harmful to cells. Our findings indicate that the inlet design and flow velocity are crucial and should be well considered in fabricating microfluidic devices for cell studies.

  10. Micro and Nanofluidic devices: For Single cell and DNA analysis

    OpenAIRE

    Mokkapati, V. R. S. S.

    2011-01-01

    Research in the field of Micro/nanofluidics has been extensively carried out for the last few years. With the available technological advancements today many complex systems can be fabricated in a more efficient and simpler way. Conventional methods in a laboratory consumes a lot of time, chemicals and in turn generates a lot of waste unlike the Lab-on-a-chip (LOC) devices where all the processes are carried out on a small chip with small drops of chemicals, negligible wastes and in minimum t...

  11. A microfluidic device for epigenomic profiling using 100 cells.

    Science.gov (United States)

    Cao, Zhenning; Chen, Changya; He, Bing; Tan, Kai; Lu, Chang

    2015-10-01

    The sensitivity of chromatin immunoprecipitation (ChIP) assays poses a major obstacle for epigenomic studies of low-abundance cells. Here we present a microfluidics-based ChIP-seq protocol using as few as 100 cells via drastically improved collection of high-quality ChIP-enriched DNA. Using this technology, we uncovered many new enhancers and super enhancers in hematopoietic stem and progenitor cells from mouse fetal liver, suggesting that enhancer activity is highly dynamic during early hematopoiesis. PMID:26214128

  12. Verification of scattering parameter measurements in waveguides up to 325 GHz including highly-reflective devices

    Science.gov (United States)

    Schrader, T.; Kuhlmann, K.; Dickhoff, R.; Dittmer, J.; Hiebel, M.

    2011-07-01

    Radio-frequency (RF) scattering parameters (S-parameters) play an important role to characterise RF signal transmission and reflection of active and passive devices such as transmission lines, components, and small-signal amplifiers. Vector network analysers (VNAs) are employed as instrumentation for such measurements. During the last years, the upper frequency limit of this instrumentation has been extended up to several hundreds of GHz for waveguide measurements. Calibration and verification procedures are obligatory prior to the VNA measurement to achieve accurate results and/or to obtain traceability to the International System of Units (SI). Usually, verification is performed by measuring well-matched devices with known S-parameters such as attenuators or short precision waveguide sections (shims). In waveguides, especially above 110 GHz, such devices may not exist and/or are not traceably calibrated. In some cases, e.g. filter networks, the devices under test (DUT) are partly highly reflective. This paper describes the dependency of the S-parameters a) on the calibration procedure, b) on the applied torque to the flange screws during the mating process of the single waveguide elements. It describes further c) how highly-reflective devices (HRD) can be used to verify a calibrated VNA, and d) how a measured attenuation at several hundreds of GHz can be substituted by a well-known coaxial attenuation at 279 MHz, the intermediate frequency (IF) of the VNA, to verify the linearity. This work is a contribution towards traceability and to obtain knowledge about the measurement uncertainty of VNA instrumentation in the millimetre-wave range.

  13. Cohesion and device reliability in organic bulk heterojunction photovoltaic cells

    KAUST Repository

    Brand, Vitali

    2012-04-01

    The fracture resistance of P3HT:PC 60BM-based photovoltaic devices are characterized using quantitative adhesion and cohesion metrologies that allow identification of the weakest layer or interface in the device structure. We demonstrate that the phase separated bulk heterojunction layer is the weakest layer and report quantitative cohesion values which ranged from ∼1 to 20 J m -2. The effects of layer thickness, composition, and annealing treatments on layer cohesion are investigated. Using depth profiling and X-ray photoelectron spectroscopy on the resulting fracture surfaces, we examine the gradient of molecular components through the thickness of the bulk heterojunction layer. Finally, using atomic force microscopy we show how the topography of the failure path is related to buckling of the metal electrode and how it develops with annealing. The research provides new insights on how the molecular design, structure and composition affect the cohesive properties of organic photovoltaics. © 2011 Elsevier B.V. All rights reserved.

  14. Photon and neutron doses of the personnel using moisture and density measurement devices

    International Nuclear Information System (INIS)

    The objective of this study is to present the evolution of the photon doses received by the workers who use mobile devices for measuring the moisture and the density in various materials and to estimate the neutron doses. The workers employed in more than 30 construction companies in Greece were 76 in 2004. The devices used for that purpose incorporate a 137Cs source for density measurements and an 241Am-Be source for moisture measurements of soil, asphalt or concrete. Photon and neutron measurements were performed occasionally during the on site inspections. The results of the measurements showed that the photon and neutron dose rates were not negligible. The workers were monitored for photon radiation using film badges (Kodak Type 2, Holder NRPB type) till the year 2000 and then TLD badges issued by the Greek Atomic Energy Commission (GAEC), on a monthly basis. Since the neutron dose rates measured by a rem-meter were not so high, no neutron dosemeters were issued for them. Their personal dose equivalent data for photons are kept in the National Dose Registry Information System (N.D.R.I.S.) in G.A.E.C. and were used for statistical analysis for the period from 1997 till 2004. As far as the neutrons are concerned, a Monte Carlo code was used to simulate the measuring devices and the working positions in order to calculate the neutron individual doses. (authors)

  15. Photon and neutron doses of the personnel using moisture and density measurement devices

    Energy Technology Data Exchange (ETDEWEB)

    Carinou, E.; Papadomarkaki, E.; Tritakis, P.; Hourdakis, C.I.; Kamenopoulou, V. [Greek Atomic Energy Commission, Agia Paraskevi, Attiki, 60092 (Greece)

    2006-07-01

    The objective of this study is to present the evolution of the photon doses received by the workers who use mobile devices for measuring the moisture and the density in various materials and to estimate the neutron doses. The workers employed in more than 30 construction companies in Greece were 76 in 2004. The devices used for that purpose incorporate a {sup 137}Cs source for density measurements and an {sup 241}Am-Be source for moisture measurements of soil, asphalt or concrete. Photon and neutron measurements were performed occasionally during the on site inspections. The results of the measurements showed that the photon and neutron dose rates were not negligible. The workers were monitored for photon radiation using film badges (Kodak Type 2, Holder NRPB type) till the year 2000 and then TLD badges issued by the Greek Atomic Energy Commission (GAEC), on a monthly basis. Since the neutron dose rates measured by a rem-meter were not so high, no neutron dosemeters were issued for them. Their personal dose equivalent data for photons are kept in the National Dose Registry Information System (N.D.R.I.S.) in G.A.E.C. and were used for statistical analysis for the period from 1997 till 2004. As far as the neutrons are concerned, a Monte Carlo code was used to simulate the measuring devices and the working positions in order to calculate the neutron individual doses. (authors)

  16. Entropy measures of collective cell migration

    Science.gov (United States)

    Whitby, Ariadne; Parrinello, Simona; Faisal, Aldo

    2015-03-01

    Collective cell migration is a critical process during tissue formation and repair. To this end there is a need to develop tools to quantitatively measure the dynamics of collective cell migration obtained from microscopy data. Drawing on statistical physics we use entropy of velocity fields derived from dense optic flow to quantitatively measure collective migration. Using peripheral nerve repair after injury as experimental system, we study how Schwann cells, guided by fibroblasts, migrate in cord-like structures across the cut, paving a highway for neurons. This process of emergence of organised behaviour is key for successful repair, yet the emergence of leader cells and transition from a random to ordered state is not understood. We find fibroblasts induce correlated directionality in migrating Schwann cells as measured by a decrease in the entropy of motion vector. We show our method is robust with respect to image resolution in time and space, giving a principled assessment of how various molecular mechanisms affect macroscopic features of collective cell migration. Finally, the generality of our method allows us to process both simulated cell movement and microscopic data, enabling principled fitting and comparison of in silico to in vitro. ICCS, Imperial College London & MRC Clinical Sciences Centre.

  17. Test-Retest Reliability of Respiratory Resistance Measured with the Airflow Perturbation Device

    Science.gov (United States)

    Gallena, Sally K.; Solomon, Nancy Pearl; Johnson, Arthur T.; Vossoughi, Jafar; Tian, Wei

    2014-01-01

    Purpose: In this study, the authors aimed to determine reliability of the airflow perturbation device (APD) to measure respiratory resistance within and across sessions during resting tidal (RTB) and postexercise breathing in healthy athletes, and during RTB across trials within a session in athletes with paradoxical vocal fold motion (PVFM)…

  18. Design and Study of Data Acquisition System for Pulsed γ Dose Measurement Device

    Institute of Scientific and Technical Information of China (English)

    DOU; Yu-ling; YANG; Shao-hua; ZHANG; Guo-guang

    2012-01-01

    <正>A data acquisition system for online pulsed gamma dose measurement device was designed and developed (Fig. 1), and its performance was tested. The results show that the data acquisition system in both the continued and pulsed input, output electric charges and input energy have a good linear relationship. Experiments were done respectively on the XRS-3 pulsed source and re-frequency

  19. A device for spatial, temporal and contrast resolution measurement using a VDU screen

    NARCIS (Netherlands)

    Umbach, F.W.

    1983-01-01

    This paper describes a recently designed electronic eye-test device. It measures spatial, temporal and contrast resolution by means of test pictures presented on a VDU screen. The subject responds using a keyboard. The tests are fully automatic and therefore easily applied in large scale test set-up

  20. A device for spatial, temporal and contrast resolution measurement using a VDU screen

    OpenAIRE

    Umbach, F.W.

    1983-01-01

    This paper describes a recently designed electronic eye-test device. It measures spatial, temporal and contrast resolution by means of test pictures presented on a VDU screen. The subject responds using a keyboard. The tests are fully automatic and therefore easily applied in large scale test set-ups.

  1. Development of power measuring device of transmission type with dielectric for high power millimeter wave

    International Nuclear Information System (INIS)

    A power measuring device using a dielectric disk for a high power millimeter waves is investigated. In the device, a high power wave is transmitted in a waveguide and then heats the dielectric disk installed in the waveguide. The transmitted power is estimated from the temperature rise of the dielectric disk. It is a new type of power measurement device, which is not sensitive to higher modes and change of their polarization in time. It also can measure the wide power range of kW to MW levels flexibly by choosing dielectric material proper to the power level as a detector. In the report, materials that have small dielectric loss for millimeter waves are chosen, and their properties of temperature rise and millimeter wave power capacity are estimated. On the basis of these results, design of the power measurement device and fabrication of its prototype are described for practical use in the electron cyclotron heating systems for the JT-60U and JT-60SA. (author)

  2. A Simple Device for Measuring Static Compliance of Lung-Thorax Combine

    Science.gov (United States)

    Sircar, Sabyasachi

    2015-01-01

    Explaining the concept of lung compliance remains a challenge to the physiology teacher because it cannot be demonstrated easily in human subjects and all attempts until now have used only simulation models. A simple device is described in the present article to measure the compliance of the "lung-thorax" combine in human subjects with…

  3. An ultrasonic device for source to skin surface distance measurement in patient setup

    International Nuclear Information System (INIS)

    Purpose: To develop an ultrasound-based source to skin surface distance (SSD) measurement technique and device for patient setup and test its feasibility and accuracy. Methods and materials: The ultrasonic SSD measurement device (USD) prototype consists of two main parts: a probe plate with an ultrasonic transducer in the center and a control unit that displays the SSD in millimeters. The probe plate can be slid into the block tray accessory slot of any treatment machine at the time of the SSD measurement. The probe plate contains an ultrasonic transducer as both the source and the detector for measuring the distance between the transducer and the target surfaces on the basis of an echo-detecting technique. The device was calibrated by a mechanical ruler with an accuracy of 0.01 mm and corrected by an offset of 601.7 mm, which is the distance from the radiation source to the ultrasonic transducer surface for the Siemens Primus linear accelerator (Linac). The ultrasound device provided digital readout with an accuracy of ±0.1 mm for a flat surface after calibration. The SSD measurement experiments were done with the USD, an optical distance indicator (ODI), and an AKTINA 53-104 Mechanical Front Pointer (FP) on a Siemens Primus Linac with a full-sized female phantom. Ten measurements were carried out at each gantry angle of 0 deg , 52 deg , 85 deg , 90 deg , and 227 deg for anatomic locations of head, thorax, breast, and pelvis, to obtain the average values and standard deviations. Results: The comparison study with the ODI and FP showed that the USD had an accuracy of less than ±1.0 mm and that USD measurements had the minimum standard deviations among the three methods; therefore, USD gave more consistent and accurate readouts for SSD measurement. When considering the FP as a reference, the USD yields smaller deviations than the ODI for all measured locations (less than ±2 mm). The variation of USD digital readout with a room temperature change of ±2 deg C is

  4. Next Generation Solar Cells Based on Graded Bandgap Device Structures Utilising Rod-Type Nano-Materials

    Directory of Open Access Journals (Sweden)

    Imyhamy M. Dharmadasa

    2015-06-01

    Full Text Available Current solar cells under research and development utilise mainly one absorber layer limiting the photon harvesting capabilities. In order to develop next generation solar cells, research should move towards effective photon harvesting methods utilising low-cost solar energy materials. This will lead to reduce the $W−1 figure for direct solar energy conversion to electrical energy. In this work, a graded bandgap solar cell has been designed to absorb all photons from the UV, visible and IR regions. In addition, impurity PV effect and impact ionisation have been incorporated to enhance charge carrier creation within the same device. This new design has been experimentally tested using the most researched MOCVD grown GaAs/AlGaAs system, in order to confirm its validity. Devices with high Voc ~ 1175 mV and the highest possible FF ~ (0.85–0.87 have been produced, increasing the conversion efficiency to ~20% within only two growth runs. These devices were also experimentally tested for the existence of impurity PV effect and impact ionisation. The devices are PV active in complete darkness producing over 800 mV, Voc indicating the harvesting of IR radiation from the surroundings through impurity PV effect. The quantum efficiency measurements show over 140% signal confirming the contribution to PV action from impact ionisation. Since the concept is successfully proven, the low-cost and scalable electrodeposited semiconducting layers are used to produce graded bandgap solar cell structures. The utilisation of nano- and micro-rod type materials in graded bandgap devices are also presented and discussed in this paper. Preliminary work on glass/FTO/n-ZnS/n-CdS/n-CdTe/Au graded bandgap devices show 10%–12% efficient devices indicating extremely high Jsc values ~48 mA·cm−2, showing the high potential of these devices in achieving higher efficiencies. The detailed results on these low-cost and novel graded bandgap devices are presented in a separate

  5. Detector to measure neutron pulses of low yield from plasma pinch devices

    International Nuclear Information System (INIS)

    Neutron emission from pinch plasma focus devices has been found ranging from 107 neutrons per pulse with 1kJ driver up to 1012 neutrons per pulse with 1000kJ driver. The region corresponding to total neutron yield of less than 106 neutron per pulse, is unexplored. The consequence of this is that measurement of very low levels of fast neutron emission becomes very important to consider. A conventional technique is adapted to measure neutron emission produced by very short, low yield neutron pulses. This method uses a 3He proportional counter surrounded by a paraffin moderator, to measurement neutron yield (≤106 neutron/pulse) generated in a fast and very small plasma focus device designed to operate with energies of tens to hundred joules. Neutron yields as low as 5x104 neutrons per pulse were measured (author)

  6. Energy Renovation of Buildings Utilizing the U-value Meter, a New Heat Loss Measuring Device

    Directory of Open Access Journals (Sweden)

    Lars Schiøtt Sørensen

    2010-01-01

    Full Text Available A new device with the ability to measure heat loss from building facades is proposed. Yet to be commercially developed, the U-value Meter can be used as stand-alone apparatus, or in combination with thermographic-equipment. The U-value meter complements thermographs, which only reproduce surface temperature and not the heat loss distribution. There is need for a device that measures the heat loss in a quantitative manner. Convective as well as radiative heat losses are captured and measured with a five-layer thermal system. Heat losses are measured in the SI-unit W/m2K. The aim is to achieve more cost-effective building renovation, and provide a means to check the fulfillment of Building Regulation requirements with respect to stated U-values (heat transmission coefficients. In this way it should be possible to greatly reduce energy consumption of buildings.

  7. Measurement of Blood Pressure Using an Arterial Pulsimeter Equipped with a Hall Device

    OpenAIRE

    Jong-Gu Choi; Keun-Ho Kim; Woo-Beom Lee; Dong-Hyun Nam; Il-Ho Son; You-Sik Hong; Sang-Suk Lee

    2011-01-01

    To measure precise blood pressure (BP) and pulse rate without using a cuff, we have developed an arterial pulsimeter consisting of a small, portable apparatus incorporating a Hall device. Regression analysis of the pulse wave measured during testing of the arterial pulsimeter was conducted using two equations of the BP algorithm. The estimated values of BP obtained by the cuffless arterial pulsimeter over 5 s were compared with values obtained using electronic or liquid mercury BP meters. The...

  8. Measurements of magnetic anisotropy in sickle cells

    International Nuclear Information System (INIS)

    Room temperature magnetic measurements in deoxigenated sickle cells showed the existence of magnetic anisotropy, Δchi=1,29 x 10-3. This effect was supposed paramagnetic and considered to be due to the iron atoms of the hemoglobin molecules which are one over the other, forming ordered chains inside the erythrocytes. Low temperature (liquid He - 4,2K) measurements of the magnetic anisotropy of sickle cells and normal red blood cells diluted in a cryoprotector was made to confirm the paramagnetic origin of the fenomena. For that purpose it was used a superconductor magnetometer coupled to a SQUID, developed in the 'Laboratorio do Estado Solido do Departamento de Fisica da PUC-RJ'. The results obtained seem to confirm the expected paramagnetic anisotropy and, furthermore, suggest the presence of magnetic interactions among the iron atoms in the sickle cells samples. (Author)

  9. The making of pressure measurement device on heating-02 based realtime

    International Nuclear Information System (INIS)

    In order to modify the installation strand BETA Test Section Test integrated with heating-02 into a closed loop, it would require an additional system that can measure pressure changes in the closed-loop system. By making the measurement device to test the system pressure at the heating-expected 02 researchers can monitor the pressure changes that occur in the system. The pressure gauge device fabrication using manufacturing simulation methodology, the preparation of the hardware and software and test functions. Manufacturing simulation using measuring devices HIOKI DC current source Signal Source, preparation of pressure measurement devices require hardware such as pressure transducers, NI cRIO-9074, NI 9203 analog module, Computer and software LabVIEW 2011 as programming. In the test process function method is used to provide flow simulation module that is connected to the 9203 NI NI cRIO-9074. Current provision tailored to the specifics pressure transducer is 4 mA s/d 20 mA. Based on the test results obtained function value of the lowest current is 4.00 mA = 0.001 bar, and the highest current value of 20.00 mA = 4995 bar. From the results of calculations using the linear equations obtained correlation coefficient (R2) of 0.999, so it is evident that the pressure changes in LabVIEW is affected by changes in flow. The results obtained from this activity is a device that can measure the pressure in the heating-02 test. (author)

  10. Microcontroller based system for electrical breakdown time delay measurement in gas-filled devices

    International Nuclear Information System (INIS)

    This paper presents realization of a digital embedded system for measuring electrical breakdown time delay. The proposed system consists of three major parts: dc voltage supply, analog subsystem, and a digital subsystem. Any dc power source with the range from 100 to 1000 V can be used in this application. The analog subsystem should provide fast and accurate voltage switching on the testing device as well as transform the signals that represent the voltage pulse on the device and the device breakdown into the form suitable for detection by a digital subsystem. The insulated gate bipolar transistor IRG4PH40KD driven by TC429 MOSFET driver is used for high voltage switching on the device. The aim of a digital subsystem is to detect the signals from the analog subsystem and to measure the elapsed time between their occurrences. Moreover, the digital subsystem controls various parameters that influence time delay and provides fast data storage for a large number of measured data. For this propose, we used the PIC18F4550 microcontroller with a full-speed compatible universal serial bus (USB) engine. Operation of this system is verified on different commercial and custom made gas devices with different structure and breakdown mechanisms. The electrical breakdown time delay measurements have been carried out as a function of several parameters, which dominantly influence electrical breakdown time delay. The obtained results have been verified using statistical methods, and they show good agreement with the theory. The proposed system shows good repeatability, sensitivity, and stability for measuring the electrical breakdown time delay.

  11. Microcontroller based system for electrical breakdown time delay measurement in gas-filled devices

    Science.gov (United States)

    Pejović, Milić M.; Denić, Dragan B.; Pejović, Momčilo M.; Nešić, Nikola T.; Vasović, Nikola

    2010-10-01

    This paper presents realization of a digital embedded system for measuring electrical breakdown time delay. The proposed system consists of three major parts: dc voltage supply, analog subsystem, and a digital subsystem. Any dc power source with the range from 100 to 1000 V can be used in this application. The analog subsystem should provide fast and accurate voltage switching on the testing device as well as transform the signals that represent the voltage pulse on the device and the device breakdown into the form suitable for detection by a digital subsystem. The insulated gate bipolar transistor IRG4PH40KD driven by TC429 MOSFET driver is used for high voltage switching on the device. The aim of a digital subsystem is to detect the signals from the analog subsystem and to measure the elapsed time between their occurrences. Moreover, the digital subsystem controls various parameters that influence time delay and provides fast data storage for a large number of measured data. For this propose, we used the PIC18F4550 microcontroller with a full-speed compatible universal serial bus (USB) engine. Operation of this system is verified on different commercial and custom made gas devices with different structure and breakdown mechanisms. The electrical breakdown time delay measurements have been carried out as a function of several parameters, which dominantly influence electrical breakdown time delay. The obtained results have been verified using statistical methods, and they show good agreement with the theory. The proposed system shows good repeatability, sensitivity, and stability for measuring the electrical breakdown time delay.

  12. New pressure cell for ultrasonic measurements

    Science.gov (United States)

    Kepa, Michal; Huxley, Andrew; Kamenev, Konstantin

    2013-06-01

    Ultrasonic interferometry at high pressure remains a technical challenge as the small sample space requires the application of very high-frequency ultrasound. Here we present the design of a new cell developed specifically for ultrasonic measurements of single crystals at low temperatures (2K) and high pressures (5GPa). The design allows greater sample space (compared to a conventional diamond anvil cell) and simultaneous measurement of ultrasonic attenuation and velocities. Coupling the fine transducers to spherical sapphire anvils reduces background and enables different polarizations of the ultrasonic wave to be measured at the same pressure and temperature conditions. The results are used to deduce the elastic, electronic and magnetic properties of a crystal. The finite element analysis of the cell together with the pressure calibration curves and test data taken on UGe2 are presented.

  13. Measuring enzyme activity in single cells

    OpenAIRE

    Kovarik, Michelle L.; Allbritton, Nancy L.

    2011-01-01

    Seemingly identical cells can differ in their biochemical state, function and fate, and this variability plays an increasingly recognized role in organism-level outcomes. Cellular heterogeneity arises in part from variation in enzyme activity, which results from interplay between biological noise and multiple cellular processes. As a result, single-cell assays of enzyme activity, particularly those that measure product formation directly, are crucial. Recent innovations have yielded a range o...

  14. Measured and simulated performance of a ceramic micromechanical beam steering device at 94 GHz

    OpenAIRE

    Drysdale, T.D.; Walsby, E.D.; Cumming, D.R.S.

    2008-01-01

    We report the first experimental demonstration of a transmission-mode micromechanical beam steering device for use in standoff terahertz imaging and spectroscopy. The device was constructed by laminating laser-cut 96% alumina sheets to form two plates with interlocking rectangular gratings of 762 μm period and was characterized at 94 GHz in a free-space measurement setup with an automated elevation scan. Plate tilts as great as 6° deflected the transmitted beam by 6° for the transverse electr...

  15. Device for measuring the flow velocity according to the principle of Karman's vortex path

    International Nuclear Information System (INIS)

    The invention refers to a device for measuring the flow velocity of gaseous or liquid media according to the principle of Karman's vortex path by means of a resting, flow-dividing external drag body extending across the flow direction and having a plane back and a back element connected with the drag body which likewise is extended at right angles to the flow and whose flat front is arranged at a gap-forming distance from and parallel to the plane backside of the drag body. In addition, the device has at least one frequency-depending sensor for detecting the flow velocity. (orig.)

  16. Device for simultaneous measurements of the optical and dielectric properties of hydrogels

    International Nuclear Information System (INIS)

    We have designed an experimental device to simultaneously measure the light transmittance and dielectric properties of thermo-sensitive hydrogels. We have used this device to study poly(N-isopropylacrylamide) samples in order to understand the mechanism of water deliverance during the phase transition such hydrogels normally exhibit. We found that the phase transition can be observed dielectrically at low frequencies, when the isothermals obtained during the heating of the samples separate into two groups. The phenomenon occurs due to the increase of ions caused by the dissociation of water molecules released by the polymer, and corresponds to the drop of the optical transmittance

  17. The measurement of potential distribution of plasma in MM-4 fusion device

    International Nuclear Information System (INIS)

    Some experimental results of the potential distribution in MM-4 fusion device are presented by measuring the floating potential of probe. The results showed that the distribution of axial potential is asymmetrical, but the radial potential is symmetrical. There are double ion potential wells in the plasma. The depth of the deepest potential well become deeper is the strength of the magnetic field and injection current are increasing. The location of the deepest well is moved towards the device center along with the increasing of injection energy. This is different from others results. The mechanism of causing this distribution in also discussed

  18. A clip-free eyeglasses-based wearable monitoring device for measuring photoplethysmograhic signals.

    Science.gov (United States)

    Zheng, Yali; Leung, Billy; Sy, Stanley; Zhang, Yuanting; Poon, Carmen C Y

    2012-01-01

    An eyeglasses-based device has been developed in this work to acquire photoplethysmogram (PPG) from the nose bridge. This device is aimed to provide wearable physiological monitoring without uncomfortable clips frequently used in PPG measurement from finger and ear. Switching control is applied on the LED and photo detector for power saving. An experiment involving postural change and treadmill jogging among 10 healthy young subjects was carried out to evaluate the performance of the device. Electrocardiogram (ECG) and PPG from finger, ear and nose were simultaneously recorded, from which heart rate (HR) and pulse transit time (PTT) were calculated. The results show that PPG measured from nose and ear are more resistant to motion than signal from finger during exercise. In addition, the difference between PTT measured from ear and nose indicates that local vasomotor activities may exist on ear and/or nose channel, and suggests that PPG from different sites should be used for cuff-less PTT-based BP estimation. We conclude that this wearable device has great potential to be used in the healthcare management in the future. PMID:23367056

  19. Fabrication of an inexpensive photosensitive flow through device for turbidity measurement

    International Nuclear Information System (INIS)

    The aim of this study is the construction of a portable, simple to use, on-line photosensitive device which measures turbidity in water. The turbidity measuring device uses a light emitting diode, LED, light source shining on a light dependent resistor, LDR, which is connected in series to a circuit supplying a constant voltage and a digital voltmeter, DVM. Light shine through a tube containing the sample, and onto a photosensitive circuit. A clear tube of water is the BLANK and has zero absorbance. A fraction of the incident light that i obstructed by the turbidity of the sample can be used for calculable determination of turbidity in water. The turbidity is related to the absorbance reading, following Beer's law. The amount of incident and transmitted light are expressed in voltage units, by a voltmeter. The sample is delivered into the sampling chamber by a rubber tubing attached to a power head submersible pump which is immersed in the pool of water to be sampled. The instrument shows excellent response over the range o turbidity values (5NTU to 180 NTU). Linearity (R2=0.95) has been achieved using the device, working with 6 trials per particular NTU value. The NTU readings of the urbidity meter were calibrated against solutions of varying NTU's measured using a HORIBA multi-parameter probe. The other features of the device include: simplicity of operation, low-cost, rugged, handy and can be used in on-line and flow mode applications. (author)

  20. CdSe Quantum Dots for Solar Cell Devices

    Directory of Open Access Journals (Sweden)

    A. B. Kashyout

    2012-01-01

    Full Text Available CdSe quantum dots have been prepared with different sizes and exploited as inorganic dye to sensitize a wide bandgap TiO2 thin films for QDs solar cells. The synthesis is based on the pyrolysis of organometallic reagents by injection into a hot coordinating solvent. This provides temporally discrete nucleation and permits controlled growth of macroscopic quantities of nanocrystallites. XRD, HRTEM, UV-visible, and PL were used to characterize the synthesized quantum dots. The results showed CdSe quantum dots with sizes ranging from 3 nm to 6 nm which enabled the control of the optical properties and consequently the solar cell performance. Solar cell of 0.08% performance under solar irradiation with a light intensity of 100 mW/cm2 has been obtained. CdSe/TiO2 solar cells without and with using mercaptopropionic acid (MPA as a linker between CdSe and TiO2 particles despite a Voc of 428 mV, Jsc of 0.184 mAcm-2, FF of 0.57, and η of 0.05% but with linker despite a Voc of 543 mV, Jsc of 0.318 mAcm-2 , FF of 0.48, and η of 0.08%, respectively.

  1. How Cells Measure Length on Subcellular Scales.

    Science.gov (United States)

    Marshall, Wallace F

    2015-12-01

    Cells are not just amorphous bags of enzymes, but precise and complex machines. With any machine, it is important that the parts be of the right size, yet our understanding of the mechanisms that control size of cellular structures remains at a rudimentary level in most cases. One problem with studying size control is that many cellular organelles have complex 3D structures that make their size hard to measure. Here we focus on linear structures within cells, for which the problem of size control reduces to the problem of length control. We compare and contrast potential mechanisms for length control to understand how cells solve simple geometry problems. PMID:26437596

  2. A droplet-to-digital (D2D) microfluidic device for single cell assays.

    Science.gov (United States)

    Shih, Steve C C; Gach, Philip C; Sustarich, Jess; Simmons, Blake A; Adams, Paul D; Singh, Seema; Singh, Anup K

    2015-01-01

    We have developed a new hybrid droplet-to-digital microfluidic platform (D2D) that integrates droplet-in-channel microfluidics with digital microfluidics (DMF) for performing multi-step assays. This D2D platform combines the strengths of the two formats-droplets-in-channel for facile generation of droplets containing single cells, and DMF for on-demand manipulation of droplets including control of different droplet volumes (pL-μL), creation of a dilution series of ionic liquid (IL), and parallel single cell culturing and analysis for IL toxicity screening. This D2D device also allows for automated analysis that includes a feedback-controlled system for merging and splitting of droplets to add reagents, an integrated Peltier element for parallel cell culture at optimum temperature, and an impedance sensing mechanism to control the flow rate for droplet generation and preventing droplet evaporation. Droplet-in-channel is well-suited for encapsulation of single cells as it allows the careful manipulation of flow rates of aqueous phase containing cells and oil to optimize encapsulation. Once single cell containing droplets are generated, they are transferred to a DMF chip via a capillary where they are merged with droplets containing IL and cultured at 30 °C. The DMF chip, in addition to permitting cell culture and reagent (ionic liquid/salt) addition, also allows recovery of individual droplets for off-chip analysis such as further culturing and measurement of ethanol production. The D2D chip was used to evaluate the effect of IL/salt type (four types: NaOAc, NaCl, [C2mim] [OAc], [C2mim] [Cl]) and concentration (four concentrations: 0, 37.5, 75, 150 mM) on the growth kinetics and ethanol production of yeast and as expected, increasing IL concentration led to lower biomass and ethanol production. Specifically, [C2mim] [OAc] had inhibitory effects on yeast growth at concentrations 75 and 150 mM and significantly reduced their ethanol production compared to cells grown

  3. Current Density Distribution Mapping in PEM Fuel Cells as An Instrument for Operational Measurements

    Directory of Open Access Journals (Sweden)

    Martin Geske

    2010-04-01

    Full Text Available A newly developed measurement system for current density distribution mapping has enabled a new approach for operational measurements in proton exchange membrane fuel cells (PEMFC. Taking into account previously constructed measurement systems, a method based on a multi layer printed circuit board was chosen for the development of the new system. This type of system consists of a sensor, a special electronic device and the control and visualization PC. For the acquisition of the current density distribution values, a sensor device was designed and installed within a multilayer printed circuit board with integrated shunt resistors. Varying shunt values can be taken into consideration with a newly developed and evaluated calibration method. The sensor device was integrated in a PEM fuel cell stack to prove the functionality of the whole measurement system. A software application was implemented to visualize and save the measurement values. Its functionality was verified by operational measurements within a PEMFC system. Measurement accuracy and possible negative reactions of the sensor device during PEMFC operation are discussed in detail in this paper. The developed system enables operational measurements for different operating phases of PEM fuel cells. Additionally, this can be seen as a basis for new opportunities of optimization for fuel cell design and operation modes.

  4. Jules Horowitz Reactor Project- Fuel irradiation device, innovative instrumentation proposal for experimental phenomena real time measurement

    International Nuclear Information System (INIS)

    The fuel irradiation devices used for the tests or rods allow reproducing at small scales the conditions of the studied nuclear reactors (as LWR type). During the irradiation phase, the tested fuel rod can be stressed due to thermal, mechanical, nuclear effects which can modify its geometry (dilatation, swelling effects). After the test, the return to normal conditions can have as consequence the disappearance of the phenomenon or give access to partial information (final deformation). Generally, to follow the phenomena related to the irradiation phase, the experimental rod contained in the test device is instrumented with thermocouples and LVDT. As complement of this instrumentation, new sensors using innovating technologies are studied (deformation sensor integrating optical fibres). Through the example of a fuel irradiation device foreseen for the JHR, this paper aims to describe the present development of an innovating instrumentation with the objective to measure, in real time and under flux, the fuel rod deformation phenomena during a ramp test

  5. Device for measurement of power and shape of radio frequency pulses in nuclear magnetic resonance

    International Nuclear Information System (INIS)

    A design of an instrument to measure the power and shape of radio frequency (RF) pulses operating in a broad frequency range is described. The device is capable of measuring the pulse power up to 500 W of both CW and extremely short (∼1 μs) RF pulses of arbitrary period. The pulse envelope can be observed on a logarithmic scale on a corresponding instrument output using an inexpensive storage oscilloscope. The instrument consists of a coaxial measurement head, the RF processing circuits and an AD conversion and display unit. The whole device is based on widely available integrated circuits; thus, good reproducibility and adaptability of the design is ensured. Since the construction is intended to be used in particular (but not solely) in nuclear magnetic resonance spectroscopy, we found it useful to provide a demonstration of two typical usage scenarios. Other application fields may comprise magnetic resonance imaging, radar and laser technology, power amplifier testing, etc. (technical design note)

  6. A microfluidic cell-trapping device for single-cell tracking of host-microbe interactions.

    Science.gov (United States)

    Delincé, Matthieu J; Bureau, Jean-Baptiste; López-Jiménez, Ana Teresa; Cosson, Pierre; Soldati, Thierry; McKinney, John D

    2016-08-16

    The impact of cellular individuality on host-microbe interactions is increasingly appreciated but studying the temporal dynamics of single-cell behavior in this context remains technically challenging. Here we present a microfluidic platform, InfectChip, to trap motile infected cells for high-resolution time-lapse microscopy. This approach allows the direct visualization of all stages of infection, from bacterial uptake to death of the bacterium or host cell, over extended periods of time. We demonstrate the utility of this approach by co-culturing an established host-cell model, Dictyostelium discoideum, with the extracellular pathogen Klebsiella pneumoniae or the intracellular pathogen Mycobacterium marinum. We show that the outcome of such infections is surprisingly heterogeneous, ranging from abortive infection to death of the bacterium or host cell. InfectChip thus provides a simple method to dissect the time-course of host-microbe interactions at the single-cell level, yielding new insights that could not be gleaned from conventional population-based measurements. PMID:27425421

  7. Device for measuring the exposure time in dental X-ray - Cronox

    International Nuclear Information System (INIS)

    The Centro Regional de Ciencias Nucleares do Nordeste (CRCN-NE) developed a test device for monitoring the X-ray beam in dental equipment to its application in quality control programs. This device, called Odontologic Dosimetric Card (CDO of Cartao Dosimetrico Odontologico in Portuguese) uses thermoluminescent dosimeters (TLD) for the measurement of some parameters of the X-ray beam as the entrance surface dose, the peak tension and half value layer (HVL). Radiographic films record the size of the radiation field. However, the TLD does not allow the assessment of exposure time, a parameter that complements the requirements of the Diretrizes de Protecao Radiologica em Radiodiagnostico Medico e Odontologico of Department of Health in Brazil for such equipment. Thus was developed a system based on sensitivity to ionizing radiation of phototransistors for measurement of exposure time when a patient is put in a clinical dental radiography. The system, called CRONOX was sized to be inserted within the CDO. The results showed that the measuring error had developed for less than 3% when compared to reference values obtained with the Tektronix digital oscilloscope, TDS2022 model. The readings obtained with the CRONOX were also compared with the nominal values selected in the X-ray equipment and with the values measured with the instrument of trade PTW Diavolt Universal. The results showed that the measuring device developed showed a maximum deviation of 5.92% on the nominal value selected, while for the instrument of PTW was 17.86%. (author)

  8. Fiber - Optic Devices as Temperature Sensors for Temperature Measurements in AC Magnetic Fields

    Science.gov (United States)

    Rablau, Corneliu; Lafrance, Joseph; Sala, Anca

    2007-10-01

    We report on the investigation of several fiber-optic devices as potential sensors for temperature measurements in AC magnetic fields. Common temperature sensors, such as thermocouples, thermistors or diodes, will create random and/or systematic errors when placed in a magnetic field. A DC magnetic field is susceptible to create a systematic offset to the measurement, while in an AC magnetic field of variable frequency random errors which cannot be corrected for can also be introduced. Fiber-Bragg-gratings and thin film filters have an inherent temperature dependence. Detrimental for their primary applications, the same dependence allows one to use such devices as temperature sensors. In an AC magnetic field, they present the advantage of being immune to electromagnetic interference. Moreover, for fiber-Bragg-gratings, the shape factor and small mass of the bare-fiber device make it convenient for temperature measurements on small samples. We studied several thin-film filters and fiber-Bragg-gratings and compared their temperature measurement capabilities in AC magnetic fields of 0 to 150 Gauss, 0 to 20 KHz to the results provided by off-the-shelf thermocouples and thermistor-based temperature measurement systems.

  9. Device for measuring the exposure time in dental X-ray - Cronox

    Energy Technology Data Exchange (ETDEWEB)

    Menezes, Claudio J.M.; Santos, Luiz A.P. dos, E-mail: cjmm@cnen.gov.b [Centro Regional de Ciencias Nucleares (CRCN-NE/CNEN-PE), Recife, PE (Brazil)

    2009-07-01

    The Centro Regional de Ciencias Nucleares do Nordeste (CRCN-NE) developed a test device for monitoring the X-ray beam in dental equipment to its application in quality control programs. This device, called Odontologic Dosimetric Card (CDO of Cartao Dosimetrico Odontologico in Portuguese) uses thermoluminescent dosimeters (TLD) for the measurement of some parameters of the X-ray beam as the entrance surface dose, the peak tension and half value layer (HVL). Radiographic films record the size of the radiation field. However, the TLD does not allow the assessment of exposure time, a parameter that complements the requirements of the Diretrizes de Protecao Radiologica em Radiodiagnostico Medico e Odontologico of Department of Health in Brazil for such equipment. Thus was developed a system based on sensitivity to ionizing radiation of phototransistors for measurement of exposure time when a patient is put in a clinical dental radiography. The system, called CRONOX was sized to be inserted within the CDO. The results showed that the measuring error had developed for less than 3% when compared to reference values obtained with the Tektronix digital oscilloscope, TDS2022 model. The readings obtained with the CRONOX were also compared with the nominal values selected in the X-ray equipment and with the values measured with the instrument of trade PTW Diavolt Universal. The results showed that the measuring device developed showed a maximum deviation of 5.92% on the nominal value selected, while for the instrument of PTW was 17.86%. (author)

  10. Use of Surface Enhanced Blocking (SEB) Electrodes for Microbial Cell Lysis in Flow-Through Devices

    OpenAIRE

    Talebpour, Abdossamad; Maaskant, Robert; Khine, Aye Aye; Alavie, Tino

    2014-01-01

    By simultaneously subjecting microbial cells to high amplitude pulsed electric fields and flash heating of the cell suspension fluid, effective release of intracellular contents was achieved. The synergistic effect of the applied electric field and elevated temperature on cell lysis in a flow-through device was demonstrated for Gram-negative and Gram-positive bacteria, and Mycobacterium species. The resulting lysate is suitable for downstream nucleic acid amplification and detection without r...

  11. Precision neutron flux measurements and applications using the Alpha Gamma device

    Science.gov (United States)

    Anderson, Eamon

    2016-03-01

    The Alpha Gamma device is a totally-absorbing 10 B neutron detector designed to measure the absolute detection efficiency of a thin-film lithium neutron monitor on a monoenergetic neutron beam. The detector has been shown to measure neutron fluence with an absolute accuracy of 0.06%. This capability has been used to perform the first direct, absolute measurement of the 6Li(n,t) 4He cross section at sub-thermal energy, improve the neutron fluence determination in a past beam neutron lifetime measurement by a factor of five, and is being used to calibrate the neutron monitors for use in the upcoming beam neutron lifetime measurement BL2 (NIST Beam Lifetime 2). The principle of the measurement method will presented and the applications will be discussed. We would like to acknowledge support of this research through the NSF-PHY-1068712 Grant as well as the NIST Precision Measurement Grant program.

  12. Gram-scale Plutonium Samples Measured by Experimental Device of Four Detectors Well-type Fast Neutron Coincidence Measurement

    Institute of Scientific and Technical Information of China (English)

    LIU; Guo-rong; LIANG; Qing-lei; LI; Jing-huai; LI; An-li

    2013-01-01

    Experimental device of four detectors well-type fast neutron coincidence measurement(see Fig.1)consists of four?127 mm×50.8 mm BC501A liquid scintillation detectors,DC271A digitizer and other circuits.Application program simultaneously acquires the waveform of each pulse output from each detector,and identifies each pulse from neutron or?particle by offline model,and gets their arrival timing.

  13. Cell culture device and microchamber which can be monitored using nuclear magnetic resonance

    OpenAIRE

    Celda-Muñoz, Bernardo; Esteve-Moya, Vicent; Sancho-Bielsa, Francisco; Villa Sanz, Rosa; Fernández Ledesma, Luis José; Berganzo Ruiz, Javier

    2010-01-01

    [EN] The invention relates to a cell culture device and microchamber which can be monitored using nuclear magnetic resonance and other imaging techniques, in which the culture microchamber is encapsulated and housed inside a chip. The microchamber and the device are easy for the user to handle, allowing same to be handled or repositioned without requiring complex mounting operations. In addition, the invention allows cultures to be studied for long periods, great...

  14. Efficiency improvement in thin film solar cell devices with oxygen containing absorber layer.

    OpenAIRE

    Emziane, M.; Durose, K; Halliday, D.P.; Bosio, N.; Romeo, N.

    2005-01-01

    The CdTe/CdS solar cell devices were grown using a dry process consisting of sputtering for the transparent conducting oxide and CdS window layers, and close-space sublimation for CdTe absorber layer. These devices were back contacted using Mo/Sb2Te3 sputtered layers following the CdCl2 activation process carried out in air. It was shown that when oxygen is intentionally introduced in the CdTe layer during its growth, this leads to a significant improvement in all the device parameters yieldi...

  15. A Cell Library Methodology for Co-Design of MEMS Package-Device

    International Nuclear Information System (INIS)

    Results from both experimental and numerical studies have already shown the significant package effects on the performance and the reliability of MEMS devices. To enable the theoretical predictions of these packaging effects, a compact joint model of an entire packaged MEMS device is established based on the Cell Library Concept and the Nodal Analysis Method. This modeling methodology greatly simplifies the package-device co-design work compared with the conventional numerical ways, and its precision is guaranteed due to its clarity in the physical nature

  16. Research on measurement of lateral dimension based on digital micromirror device

    Science.gov (United States)

    Yu, Qing; Cui, Chang-cai; Fan, Wei; Huang, Fu-gui

    2015-02-01

    For better machining and electrical characteristic, the complex surfaces topography of some delicate machining tools and electronic components should be acquired precisely, including shape and size of microstructure on surface of engineering material or precision component from microscopic view, and relationship between microstructures from macroscopic viewpoint, such as spaces, distribution and so on. This so called multiscale measurement has been greatly focusing by experts and scholars from home and abroad. People researched this novel measurement in several ways: (1) putting different sensors together, which had different resolution and measuring range; (2) applying software technology, include wavelet theory, fractal theory and image mosaicing technology, to solve this multi-scale measurement problem. However, it's difficult to cooperate with many different sensors in multi-sensors measurement technology, and mathematical modeling is very complicated in software technology. This paper used Digital Micromirror Device (DMD) as a multiscale measuring tool, and a method of measurement on lateral dimension has been proposed. As an excellent optical modulation device, DMD could modulate incident light to line structure light. Owing to controlling flexibility of DMD, the parameters of the line structure light, include line width, light intensity and scanning frequency, could be modulated by programming. This project has solved the problem of measurement error due to the angle between line structure light and field of view of specimen, and the results of experiment proved that, this method by DMD acquired lateral dimension data conveniently.

  17. A New Cuffless Device for Measuring Blood Pressure: A Real-Life Validation Study

    Science.gov (United States)

    Schoot, Tessa S; Weenk, Mariska; van de Belt, Tom H; Engelen, Lucien JLPG; van Goor, Harry

    2016-01-01

    Background Cuffless blood pressure (BP) monitoring devices, based on pulse transit time, are being developed as an easy-to-use, more convenient, fast, and relatively cheap alternative to conventional BP measuring devices based on cuff occlusion. Thereby they may provide a great alternative to BP self-measurement. Objective The objective of our study was to evaluate the performance of the first release of the Checkme Health Monitor (Viatom Technology), a cuffless BP monitor, in a real-life setting. Furthermore, we wanted to investigate whether the posture of the volunteer and the position of the device relative to the heart level would influence its outcomes. Methods Study volunteers fell into 3 BP ranges: high (>160 mmHg), normal (130–160 mmHg), and low (International Protocol (ESH-IP) for the validation of BP measurement devices. After calibrating the Checkme device, we measured systolic BP with Checkme and a validated, oscillometric reference BP monitor (RM). Measurements were performed in randomized order both in supine and in sitting position, and with Checkme at and above heart level. Results We recruited 52 volunteers, of whom we excluded 15 (12 due to calibration failure with Checkme, 3 due to a variety of reasons). The remaining 37 volunteers were divided into low (n=14), medium (n=13), and high (n=10) BP ranges. There were 18 men and 19 women, with a mean age of 54.1 (SD 14.5) years, and mean recruitment systolic BP of 141.7 (SD 24.7) mmHg. BP results obtained by RM and Checkme correlated well. In the supine position, the difference between the RM and Checkme was >5 mmHg in 17 of 37 volunteers (46%), of whom 9 of 37 (24%) had a difference >10 mmHg and 5 of 37 (14%) had a difference >15 mmHg. Conclusions BP obtained with Checkme correlated well with RM BP, particularly in the position (supine) in which the device was calibrated. These preliminary results are promising for conducting further research on cuffless BP measurement in the clinical and

  18. Measuring chamber of the device for determination of the wear particle radioactivity

    International Nuclear Information System (INIS)

    Proposed is a measuring chamber for a device designed for determining radioactivity of wear particles in the system of lubrication of an internal-combustion engine. The chamber consists of of a case with two chambers for supplying oil to a cylindrical cavity of the chamber and of one channel for offtake from the cavity. A characteristic feature of the invention is that for increasing the accuracy of measurements the supplying channels are tangetial relative to the internal surface of the cavity, and the offtake channel is radial and located between them. The application of the chamber decrease measurement errors from 20-30% to 5-6%

  19. DEVICE FOR MEASURING OF THERMAL LENS PARAMETERS IN LASER ACTIVE ELEMENTS WITH A PROBE BEAM METHOD

    Directory of Open Access Journals (Sweden)

    A. N. Zakharova

    2015-01-01

    Full Text Available We have developed a device for measuring of parameters of thermal lens (TL in laser active elements under longitudinal diode pumping. The measurements are based on the probe beam method. This device allows one to determine sign and optical power of the lens in the principal meridional planes, its sensitivity factor with respect to the absorbed pump power and astigmatism degree, fractional heat loading which make it possible to estimate integral impact of the photoelastic effect to the formation of TL in the laser element. The measurements are performed in a linearly polarized light at the wavelength of 532 nm. Pumping of the laser element is performed at 960 nm that makes it possible to study laser materials doped with Yb3+ and (Er3+, Yb3+ ions. The precision of measurements: for sensitivity factor of TL – 0,1 m-1/W, for astigmatism degree – 0,2 m-1/W, for fractional heat loading – 5 %, for the impact of the photoelastic effect – 0,5 × 10-6 K-1. This device is used for characterization of thermal lens in the laser active element from an yttrium vanadate crystal, Er3+,Yb3+:YVO .

  20. Spectroscopic measurement to study two-fluid relaxation in an internal coil device Mini-RT

    International Nuclear Information System (INIS)

    Mahajan-Yoshida has developed a new relaxation theory, by taking two-fluid effect into account. This theory indicates that the plasma flow confines high beta plasma. We have constructed an internal coil device Mini-RT with high temperature superconductor (HTS) coil, and are expecting the high beta plasma with the fast toroidal plasma flow by inducing the radial electric field. In order to measure the radial profile of the plasma flow we introduced a spectroscopy. By setting up two cylindrical lenses between a monochromator and a charge-coupled device (CCD) detector, we could not only correct astigmatism of the monochromator but also increase the resolution of wavelength up to 2.55 pm/pixel which is equal to the measurement of the plasma flow up to 1.6 x 103 m/s. Additionally we are setting up an opposed fiber array for an accurate measurement. In the Mini-RT device the plasma was produced by 2.45 GHz ECH (Electron Cyclotron Heating) system with the power of 2.6 kW. Typical electron density and temperature are more than 1016 m-3 and 10-20 eV, respectively. The ion temperature measured by this spectroscopy system was 1.0 ± 0.3 eV and the plasma flow velocity was comparable to the resolution of this spectroscopic system. Although the plasma should flow to the toroidal direction by the ∇B/curvature drift in the internal coil device, the drift velocity of 1.3 x 103 m/s is not detectable with this spectroscopy. If the radial electric field of 160 V/m or more is induced in the plasma, the plasma flow due to the E x B drift could be measured with this system. (author)

  1. Results of the development of electrochemical cells for the measurement of oxygen activity in liquid sodium

    International Nuclear Information System (INIS)

    Results of the development and testing of electrochemical cells for the measurement of oxygen activity in liquid sodium are given. A ThO2-Y2O3 solid electrolyte of high corrosion resistance in liquid sodium has been used for the construction of the cells. A design, which reduces thermal and mechanical stresses to the cells, has been applicated. A device 'Oxylyt' has been developed for reading the cell signals. During the period of development 180 electrochemical cells and about 10 devices 'Oxylyt' have been tested. The investigations were performed at experimental sodium loops, at the radioactive circuit of the reactor BR-10 and at the second circuit of the reactor station BN-350. Recommendation are given for the application of the cells for oxygen measurement in sodium at experimental rigs and industrial stations. (author)

  2. Development of an inner profile measurement instrument using a ring beam device

    Science.gov (United States)

    Yoshizawa, T.; Wakayama, T.

    2010-11-01

    Inner profile measurement is an important matter in such fields as medicine, dentistry and anthropology as well as mechanical engineering and other industrial applications. Here we describe recent development of our measurement principle for inner diameter of pipes and/or holes. The key device in this technique is a ring beam device which consists of a conical mirror and a laser diode. And the fundamental principle is based on optical sectioning without using any contact type stylus. The optically sectioned profile of an inner wall of a pipe-like object is analyzed to give the inner profile in addition to the inner diameter. This optical instrument with a simple and small configuration is now under development for practical uses. In our hitherto trial experimental works, the availability of this instrument has been evaluated in many cases and availability for practical applications is expected, especially, for measurement and inspection of mechanical components and elements besides pipes. This ring beam device consisting of a conical mirror and a LD is assembled to form a disk-like light sheet. We show measurement result of pipes and holes, and, at the same time, report a compact inner profile measuring instrument at this point. Both the ring beam device and a miniaturized CCD camera are fabricated into a glass tube. Availability of this instrument is shown by measuring the inner profiles of various pipes. In response to this trial, there appeared a strong request that not only the internal but external profiles should be measured simultaneously. Therefore we propose potentially possible method for measurement of external profile at the same time with internal profile. If one pair of concave mirrors are used in our arrangement, external profile is captured. In combination with inner profile measurement technique, simultaneous measurement of inner and outer profiles becomes attainable. A measurement result on a bevel gear shows availability of here proposed

  3. Towards autonomous lab-on-a-chip devices for cell phone biosensing.

    Science.gov (United States)

    Comina, Germán; Suska, Anke; Filippini, Daniel

    2016-03-15

    Modern cell phones are a ubiquitous resource with a residual capacity to accommodate chemical sensing and biosensing capabilities. From the different approaches explored to capitalize on such resource, the use of autonomous disposable lab-on-a-chip (LOC) devices-conceived as only accessories to complement cell phones-underscores the possibility to entirely retain cell phones' ubiquity for distributed biosensing. The technology and principles exploited for autonomous LOC devices are here selected and reviewed focusing on their potential to serve cell phone readout configurations. Together with this requirement, the central aspects of cell phones' resources that determine their potential for analytical detection are examined. The conversion of these LOC concepts into universal architectures that are readable on unaccessorized phones is discussed within this context. PMID:26569446

  4. Hierarchical structural health monitoring system combining a fiber optic spinal cord network and distributed nerve cell devices

    Science.gov (United States)

    Minakuchi, Shu; Tsukamoto, Haruka; Takeda, Nobuo

    2009-03-01

    This study proposes novel hierarchical sensing concept for detecting damages in composite structures. In the hierarchical system, numerous three-dimensionally structured sensor devices are distributed throughout the whole structural area and connected with the optical fiber network through transducing mechanisms. The distributed "sensory nerve cell" devices detect the damage, and the fiber optic "spinal cord" network gathers damage signals and transmits the information to a measuring instrument. This study began by discussing the basic concept of the hierarchical sensing system thorough comparison with existing fiber optic based systems and nerve systems in the animal kingdom. Then, in order to validate the proposed sensing concept, impact damage detection system for the composite structure was proposed. The sensor devices were developed based on Comparative Vacuum Monitoring (CVM) system and the Brillouin based distributed strain sensing was utilized to gather the damage signals from the distributed devices. Finally a verification test was conducted using prototype devices. Occurrence of barely visible impact damage was successfully detected and it was clearly indicated that the hierarchical system has better repairability, higher robustness, and wider monitorable area compared to existing systems utilizing embedded optical fiber sensors.

  5. On-chip lysis of mammalian cells through a handheld corona device.

    Science.gov (United States)

    Escobedo, C; Bürgel, S C; Kemmerling, S; Sauter, N; Braun, T; Hierlemann, A

    2015-07-21

    On-chip lysis is required in many lab-on-chip applications involving cell studies. In these applications, the complete disruption of the cellular membrane and a high lysis yield is essential. Here, we present a novel approach to lyse cells on-chip through the application of electric discharges from a corona handheld device. The method only requires a microfluidic chip and a low-cost corona device. We demonstrate the effective lysis of BHK and eGFP HCT 116 cells in the sub-second time range using an embedded microelectrode. We also show cell lysis of non-adherent K562 leukemia cells without the use of an electrode in the chip. Cell lysis has been assessed through the use of bright-field microscopy, high-speed imaging and cell-viability fluorescence probes. The experimental results show effective cell lysis without any bubble formation or significant heating. Due to the simplicity of both the components involved and the lysis procedure, this technique offers an inexpensive lysis option with the potential for integration into lab-on-a-chip devices. PMID:26055165

  6. W-state Analyzer and Multi-party Measurement-device-independent Quantum Key Distribution

    Science.gov (United States)

    Zhu, Changhua; Xu, Feihu; Pei, Changxing

    2015-12-01

    W-state is an important resource for many quantum information processing tasks. In this paper, we for the first time propose a multi-party measurement-device-independent quantum key distribution (MDI-QKD) protocol based on W-state. With linear optics, we design a W-state analyzer in order to distinguish the four-qubit W-state. This analyzer constructs the measurement device for four-party MDI-QKD. Moreover, we derived a complete security proof of the four-party MDI-QKD, and performed a numerical simulation to study its performance. The results show that four-party MDI-QKD is feasible over 150 km standard telecom fiber with off-the-shelf single photon detectors. This work takes an important step towards multi-party quantum communication and a quantum network.

  7. 3D strain measurement in electronic devices using through-focal annular dark-field imaging

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Suhyun; Jung, Younheum; Lee, Sungho; Jung Kim, Joong; Byun, Gwangseon; Lee, Sunyoung; Lee, Haebum

    2014-11-15

    Spherical aberration correction in high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) allows us to form an electron probe with reduced depth of field. Using through-focal HAADF imaging, we experimentally demonstrated 3D strain measurement in a strained-channel transistor. The strain field distribution in the channel region was obtained by scanning an electron beam over a plan-view specimen. Furthermore, the decrease in the strain fields toward the silicon substrate was revealed at different focal planes with a 5-nm focal step. These results demonstrate that it is possible to reconstruct the 3D strain field in electronic devices. - Highlights: • Three dimensional strain fields were measured using through-focal HAADF-STEM series. • The technique was applied to the channel of a plan-view strained-silicon device. • The strain values agreed with the results obtained using cross-section specimen.

  8. Tensor product extension of entanglement witnesses and their connection with measurement-device-independent entanglement witnesses

    International Nuclear Information System (INIS)

    We provide a new extension of entanglement witnesses for Cd1⊗Cd2 systems. Our construction preserves the properties of nondecomposability and spanning property of entanglement witnesses. We show how our concept of extended entanglement witnesses is connected with the idea of measurement device independent entanglement witnesses. - Highlights: • A new extension of entanglement witness (EW) for Cd1⊗Cd2 systems is provided. • This construction preserves the properties of indecomposability of EW. • This construction preserves the properties of spanning property of EW. • The idea of measurement device independent EW (MDIEW) is shown. • The connection of the concept of extended EW with the idea of MDIEW is shown

  9. W-state Analyzer and Multi-party Measurement-device-independent Quantum Key Distribution.

    Science.gov (United States)

    Zhu, Changhua; Xu, Feihu; Pei, Changxing

    2015-01-01

    W-state is an important resource for many quantum information processing tasks. In this paper, we for the first time propose a multi-party measurement-device-independent quantum key distribution (MDI-QKD) protocol based on W-state. With linear optics, we design a W-state analyzer in order to distinguish the four-qubit W-state. This analyzer constructs the measurement device for four-party MDI-QKD. Moreover, we derived a complete security proof of the four-party MDI-QKD, and performed a numerical simulation to study its performance. The results show that four-party MDI-QKD is feasible over 150 km standard telecom fiber with off-the-shelf single photon detectors. This work takes an important step towards multi-party quantum communication and a quantum network. PMID:26644289

  10. Proximity measuring device with backscattering radiation usable noticeably in remote handling or robotics and related data processing system

    International Nuclear Information System (INIS)

    The invention is aimed at a proximity measuring device whose emitter, an electroluminescent diode, is controlled by control means to emit short duration ( 1A) flashes with periods higher than 100 microseconds. Emetter-object distance can be precisely measured on an 0-30 cm interval with the help of data processing of the response given by the proximity device receiver. This device can be used in remote handling and robotics

  11. The Device for Communication in the Tool for Measurement in Boreholes

    Directory of Open Access Journals (Sweden)

    Miloš Slankamenac

    2005-10-01

    Full Text Available In this paper an implementation and test of the device for communication between Telemetry system and Surface unit with the tool for measurement of pipe diameter, fluid velocity and direction of flow in the borehole (Calliper-Fullbore Flowmeter - CFF are presented. This communication is done according to SIPLOS (Simultaneous Production Logging String protocol and it is used by Hotwell company [1] as a part of a larger system for borehole investigations.

  12. The Magnitude of Errors Associated in Measuring the Loads Applied on an Assistive Device While Walking

    OpenAIRE

    Karimi, Mohammad Taghi; Jamshidi, Nima

    2012-01-01

    Measurement of the loads exerted on the limb is a fundamental part of designing of an assistive device, which has been done by using strain gauges or a transducer. Although calculation of loads applied on an orthosis coefficients achieved from calibration is a standard way, most of researchers determined the loads based on available equations. Therefore, the aim of this research is finding the accuracy of this method with respect to calibration. Some strain gauges were attached on the lateral...

  13. A Device for Automatically Measuring and Supervising the Critical Care Patient’S Urine Output

    OpenAIRE

    Roemi Fernández; Francisco Palacios; Teodor Akinfiev; Abraham Otero

    2010-01-01

    Critical care units are equipped with commercial monitoring devices capable of sensing patients’ physiological parameters and supervising the achievement of the established therapeutic goals. This avoids human errors in this task and considerably decreases the workload of the healthcare staff. However, at present there still is a very relevant physiological parameter that is measured and supervised manually by the critical care units’ healthcare staff: urine output. This paper presents a pate...

  14. Long distance measurement-device-independent quantum key distribution with coherent-state superpositions

    OpenAIRE

    Yin, Hua-Lei; Cao, Wen-Fei; Fu, Yao; Tang, Yan-Lin; Yang LIU; Chen, Teng-yun; Chen, Zeng-Bing

    2014-01-01

    Measurement-device-independent quantum key distribution (MDI-QKD) with decoy-state method is believed to be securely applied to defeat various hacking attacks in practical quantum key distribution systems. Recently, the coherent-state superpositions (CSS) have emerged as an alternative to single-photon qubits for quantum information processing and metrology. Here, in this Letter, CSS are exploited as the source in MDI-QKD. We present an analytical method which gives two tight formulas to esti...

  15. Design of quench signals real-time surveillance and measurement system on EAST Tokamak device

    International Nuclear Information System (INIS)

    Quench surveillance and protection is very important issues for the safety operation of the EAST device. The quench signals real -time surveillance and measurement system is designed. This paper focuses on its hardware, software and design functions. The system supplies effective data for experimenters for achieving realtime display, malfunction reporting, data management. It is implemented in experiments. The system which has favorable man -machine interface is proved to be effectively. (authors)

  16. Device and performance parameters of Cu(In,Ga)(Se,S)2-based solar cells with varying i-ZnO layer thickness

    International Nuclear Information System (INIS)

    In pursuit of low-cost and highly efficient thin film solar cells, Cu(In,Ga)(Se,S)2/CdS/i-ZnO/ZnO:Al (CIGSS) solar cells were fabricated using a two-step process. The thickness of i-ZnO layer was varied from 0 to 454 nm. The current density-voltage (J-V) characteristics of the devices were measured, and the device and performance parameters of the solar cells were obtained from the J-V curves to analyze the effect of varying i-ZnO layer thickness. The device parameters were determined using a parameter extraction method that utilized particle swarm optimization. The method is a curve-fitting routine that employed the two-diode model. The J-V curves of the solar cells were fitted with the model and the parameters were determined. Results show that as the thickness of i-ZnO was increased, the average efficiency and the fill factor (FF) of the solar cells increase. Device parameters reveal that although the series resistance increased with thicker i-ZnO layer, the solar cells absorbed more photons resulting in higher short-circuit current density (Jsc) and, consequently, higher photo-generated current density (JL). For solar cells with 303-454 nm-thick i-ZnO layer, the best devices achieved efficiency between 15.24% and 15.73% and the fill factor varied between 0.65 and 0.67.

  17. Experimental research in the use of electrets in measuring effluents from rocket exhaust and a review of standard air quality measuring devices

    Science.gov (United States)

    Susko, M.

    1976-01-01

    Seven standard types of measuring devices used to obtain the chemical composition of rocket exhaust effluents were discussed. The electrets, a new measuring device, are investigated and compared with established measuring techniques. The preliminary results obtained show that electrets have multipollutant measuring capabilities, simplicity of deployment, speed of assessment or analysis, and may be an important and valuable tool in measuring pollutants from space vehicle rocket exhaust.

  18. Autonomous field-deployable device for the measurement of phosphate in natural water

    Science.gov (United States)

    Slater, Conor; Cleary, John; McGraw, Christina M.; Yerazunis, William S.; Lau, King Tong; Diamond, Dermot

    2007-09-01

    This work describes the ongoing development of an autonomous platform for the measurement of phosphate levels in river water. This device is designed to operate unassisted for one year, taking a measurement every hour and relaying the result to a laptop computer. A first generation prototype has already been developed and successfully field tested. The system contains the sampling, chemical storage, fluid handling, colorimetric data acquisition and waste storage capabilities necessary to perform the phosphate measurement. In addition to this, the device has the embedded control, GSM communications system and power supply to allow independent operation. The entire system is placed inside a compact and rugged enclosure. Further work discussed here builds on the successes of the prototype design to deliver a system capable of one full year of operation. The second generation system has been built from the ground up. Although identical in operation to the prototype its design has a greater emphasis on power efficient components and power management to allow for a longer lifetime. Other improvements include an automated two-point calibration to compensate for drift and a more rugged design to further increase the lifetime of the device.

  19. Clearance measurements on a hot cell building

    International Nuclear Information System (INIS)

    A former hot-cell facility of Siemens AG, in which dose rates in excess of 99 Sv were still prevailing in 1999, was decontaminated and subjected, except for the basement, to radiological clearance measurements. The authorities released the building for demolition in November 2004. Demolition of the upper stories of the building was started immediately afterwards using conventional techniques. For decontamination, the actual cells themselves - rooms with one-meter-thick concrete walls - had been dismantled using diamond saws and the resulting concrete blocks sent off-site for further processing. Contamination was removed from the remaining ceilings, walls and floors by knocking off the plaster and milling away the screed. Material samples were taken to confirm that decontamination had been successful. It was only then that the actual clearance measurements began. The individual rooms were grouped together into logically arranged ''clearance steps'' to simplify documentation. Most of the measurements were performed by in-situ gamma spectroscopy, with and without collimation. In addition, numerous material specimens were removed, direct surface measurements performed using contamination monitors, and wipe tests carried out. Records were made of all measurements and sorted according to clearance steps before being submitted to the competent authorities as an application for release from regulatory control. After the authorities had taken their own verification measurements they issued their approval for release. (orig.)

  20. 40 CFR 63.9525 - What are the installation, operation, and maintenance requirements for my weight measurement device?

    Science.gov (United States)

    2010-07-01

    ..., and maintenance requirements for my weight measurement device? 63.9525 Section 63.9525 Protection of... Hazardous Air Pollutants for Friction Materials Manufacturing Facilities Initial Compliance Demonstration... measurement device? (a) If you use a solvent recovery system, you must install, operate, and maintain a...

  1. Room-temperature treatments for all-inorganic nanocrystal solar cell devices

    International Nuclear Information System (INIS)

    We have developed a room-temperature solution processing approach to integrate colloidal anatase titanium dioxide nanorods (TiO2 NRs) and lead sulfide quantum dots (PbS QDs) into a heterostructured p-n junction device. To this aim we have exploited a post-deposition treatment to remove surface-adsorbed ligands by means of UV-light-irradiation of TiO2 NRs and a dilute acid treatment of PbS QDs. Here we report a systematic study on the optimization of the post-deposition treatments and device fabrication. Our approach is fully compatible with plastic device technology and is potentially useful for the integration of crystalline TiO2 as active component into disparate solar cell architectures and organic optoelectronic devices. - Highlights: • Colloidal nanocrystals offer path to low-cost manufacturing atop flexible substrates. • We fabricate an all-inorganic solar cell under room temperature treatments. • Our approach is fully compatible with plastic device technology. • It is useful for the integration of nanocrystals into disparate device architectures

  2. Room-temperature treatments for all-inorganic nanocrystal solar cell devices

    Energy Technology Data Exchange (ETDEWEB)

    Loiudice, Anna, E-mail: anna.loiudice@iit.it [Dipartimento di Matematica e Fisica " E. De Giorgi" , Università del Salento, via Arnesano, 73100 Lecce (Italy); CBN — Center for Biomolecular Nanotechnologies, Italian Institute of Technology, Energy Platform, Via Barsanti sn, 73010 Arnesano (Lecce) (Italy); Rizzo, Aurora [CBN — Center for Biomolecular Nanotechnologies, Italian Institute of Technology, Energy Platform, Via Barsanti sn, 73010 Arnesano (Lecce) (Italy); NNL CNR-Istituto Nanoscienze, c/o Distretto Tecnologico, via per Arnesano km. 5, 73100 Lecce (Italy); Corricelli, Michela [Istituto per i Processi Chimico Fisici (IPCF-CNR) Bari, c/o Department of Chemistry, University of Bari, Via Orabona 4, I-70126 Bari (Italy); Department of Chemistry, University of Bari, Via Orabona 4, I-70126 Bari (Italy); Curri, M. Lucia [Istituto per i Processi Chimico Fisici (IPCF-CNR) Bari, c/o Department of Chemistry, University of Bari, Via Orabona 4, I-70126 Bari (Italy); Belviso, Maria R. [NNL CNR-Istituto Nanoscienze, c/o Distretto Tecnologico, via per Arnesano km. 5, 73100 Lecce (Italy); Cozzoli, P. Davide [Dipartimento di Matematica e Fisica " E. De Giorgi" , Università del Salento, via Arnesano, 73100 Lecce (Italy); NNL CNR-Istituto Nanoscienze, c/o Distretto Tecnologico, via per Arnesano km. 5, 73100 Lecce (Italy); Grancini, Giulia; Petrozza, Annamaria [Center for Nano Science and Technology at PoliMi, Istituto Italiano di Tecnologia, Via Pascoli 70/3, 20133 Milano (Italy); Gigli, Giuseppe [Dipartimento di Matematica e Fisica " E. De Giorgi" , Università del Salento, via Arnesano, 73100 Lecce (Italy); CBN — Center for Biomolecular Nanotechnologies, Italian Institute of Technology, Energy Platform, Via Barsanti sn, 73010 Arnesano (Lecce) (Italy); NNL CNR-Istituto Nanoscienze, c/o Distretto Tecnologico, via per Arnesano km. 5, 73100 Lecce (Italy)

    2014-06-02

    We have developed a room-temperature solution processing approach to integrate colloidal anatase titanium dioxide nanorods (TiO{sub 2} NRs) and lead sulfide quantum dots (PbS QDs) into a heterostructured p-n junction device. To this aim we have exploited a post-deposition treatment to remove surface-adsorbed ligands by means of UV-light-irradiation of TiO{sub 2} NRs and a dilute acid treatment of PbS QDs. Here we report a systematic study on the optimization of the post-deposition treatments and device fabrication. Our approach is fully compatible with plastic device technology and is potentially useful for the integration of crystalline TiO{sub 2} as active component into disparate solar cell architectures and organic optoelectronic devices. - Highlights: • Colloidal nanocrystals offer path to low-cost manufacturing atop flexible substrates. • We fabricate an all-inorganic solar cell under room temperature treatments. • Our approach is fully compatible with plastic device technology. • It is useful for the integration of nanocrystals into disparate device architectures.

  3. Heat Transmission Coefficient Measurements in Buildings Utilizing a Heat Loss Measuring Device

    DEFF Research Database (Denmark)

    Sørensen, Lars Schiøtt

    2013-01-01

    mechanical ventilation in the “warm countries” contribute to an enormous energy consumption and corresponding CO2 emission. In order to establish the best basis for upgrading the energy performance, it is important to make measurements of the heat losses at different places on a building facade, in order to...

  4. A polymeric waveguide resonant mirror (RM) device for detection in microfluidic flow cells.

    Science.gov (United States)

    Gupta, Ruchi; Goddard, Nick J

    2013-06-01

    A novel resonant mirror (RM) device, which consisted of silica sol-gel spacer and polystyrene waveguide layers on a standard microscope slide glass substrate, was developed in this work. The device was successfully used to measure the absorption spectrum of methylene blue with a limit of detection (LOD) of at most 20.8 μM at 635 nm and a minimum detectable absorption coefficient of 0.94 cm(-1). A RM device consisting of dye-doped polystyrene waveguide layer was then demonstrated to be suitable to monitor antibody-antigen (in this case, anti-IgG and IgG) binding and was shown to be capable of detecting at least 100 nM IgG. The sensitivity of the device was estimated to be 17.27° per refractive index unit (RIU), which corresponds to a resolution of 1.45 × 10(-4) RIU for the set-up used. The RM device developed in this work can be easily integrated with microfluidic devices to identify and quantify (bio) chemical species by either absorption spectroscopy or measurement of effective optical thickness or both. In addition, the device was fabricated using a simple and low cost fabrication technique, spin coating. Hence, it can be easily mass produced. PMID:23595031

  5. Comparison of Respiratory Resistance Measurements Made with an Airflow Perturbation Device with Those from Impulse Oscillometry

    Directory of Open Access Journals (Sweden)

    J. Pan

    2013-01-01

    Full Text Available The airflow perturbation device (APD has been developed as a portable, easy to use, and a rapid response instrument for measuring respiratory resistance in humans. However, the APD has limited data validating it against the established techniques. This study used a mechanical system to simulate the normal range of human breathing to validate the APD with the clinically accepted impulse oscillometry (IOS technique. The validation system consisted of a sinusoidal flow generator with ten standardized resistance configurations that were shown to represent a total range of resistances from 0.12 to 0.95 kPa·L−1·s (1.2–9.7 cm H2O·L−1·s. Impulse oscillometry measurements and APD measurements of the mechanical system were recorded and compared at a constant airflow of 0.15 L·s−1. Both the IOS and APD measurments were accurate in assessing nominal resistance. In addition, a strong linear relationship was observed between APD measurements and IOS measurements (R2 = 0.999. A second series of measurements was made on ten human volunteers with external resistors added in their respiratory flow paths. Once calibrated with the mechanical system, the APD gave respiratory resistance measurements within 5% of IOS measurements. Because of their comparability to IOS measurements, APD measurements are shown to be valid representations of respiratory resistance.

  6. CuIn1-xGaxSe2 photovoltaic devices for tandem solar cell application

    International Nuclear Information System (INIS)

    CuIn1-xGaxSe2 (CIGS) solar cells show a good spectral response in a wide range of the solar spectrum and the bandgap of CIGS can be adjusted from 1.0 eV to 1.7 eV by increasing the gallium-to-indium ratio of the absorber. While the bandgaps of Ga-rich CIGS or CGS devices make them suitable for top or intermediate cells, the In rich CIGS or CIS devices are well suited to be used as bottom cells in tandem solar cells. The photocurrent can be adapted to the desired value for current matching in tandem cells by changing the composition of CIGS which influences the absorption characteristics. Therefore, CIGS layers with different [Ga]/[In + Ga] ratios were grown on Mo and ZnO:Al coated glass substrates. The grain size, composition of the layers, and morphology strongly depend on the Ga content. Layers with Ga rich composition exhibit smaller grain size and poor photovoltaic performance. The current densities of CIGS solar cells on ZnO:Al/glass varied from 29 mA cm-2 to 13 mA cm-2 depending on the Ga content, and 13.5% efficient cells were achieved using a low temperature process (450 deg. C ). However, Ga-rich solar cells exhibit lower transmission than dye sensitized solar cells (DSC). Prospects of tandem solar cells combining a DSC with CIGS are presented

  7. Optimized CANDU-6 cell and reactivity device supercell models for advanced fuels reactor database generation

    International Nuclear Information System (INIS)

    Highlights: • Propose an optimize 2-D model for CANDU lattice cell. • Propose a new 3-D simulation model for CANDU reactivity devices. • Implement other acceleration techniques for reactivity device simulations. • Reactivity device incremental cross sections for advanced CANDU fuels with thorium. - Abstract: Several 2D cell and 3D supercell models for reactivity device simulation have been proposed along the years for CANDU-6 reactors to generate 2-group cross section databases for finite core calculations in diffusion. Although these models are appropriate for natural uranium fuel, they are either too approximate or too expensive in terms of computer time to be used for optimization studies of advanced fuel cycles. Here we present a method to optimize the 2D spatial mesh to be used for a collision probability solution of the transport equation for CANDU cells. We also propose a technique to improve the modeling and accelerate the evaluation, in deterministic transport theory, of the incremental cross sections and diffusion coefficients associated with reactivity devices required for reactor calculations

  8. Measurement of electrostatic potential fluctuation using heavy ion beam probe in large helical device

    International Nuclear Information System (INIS)

    Heavy ion beam probe (HIBP) for large helical device (LHD) has been improved to measure the potential fluctuation in high-temperature plasmas. The spatial resolution is improved to about 10 mm by controlling the focus of a probe beam. The HIBP is applied to measure the potential fluctuation in plasmas where the rotational transform is controlled by electron cyclotron current drive. The fluctuations whose frequencies change with the time constant of a few hundreds of milliseconds and that with a constant frequency are observed. The characteristics of the latter fluctuation are similar to those of the geodesic acoustic mode oscillation. The spatial profiles of the fluctuations are also obtained.

  9. In situ devices for the measurement of anelastic effects under neutron irradiation

    International Nuclear Information System (INIS)

    Two devices for the direct measurement of the anelastic properties of metals in a reactor are described. First, a resonant cavity system has been adapted for the in-pile determination of dimensional changes, with application to strain relaxation measurements at and above room temperature. Second, an inverted torsion pendulum operated at 130 Hz at a constant amplitude has been devised for the study of internal friction in metals exposed to a fast neutron flux. The relevant detection systems and the mechanical arrangements for both apparatuses are given, together with typical recorded curves

  10. Overview of gamma spectrometry measurement devices developed by ENVINET a.s

    International Nuclear Information System (INIS)

    This paper demonstrates the development and usage of the devices designed for non- destructive radiological characterization of radioactive waste. All ..systems are based on gamma-spectrometry and are divided into two categories - stable and mobile. Stable ones involve only measurement in fixed detector - package configuration. They are used for assessment of packaged waste, mainly in drums. Mobile ones are flexible and allow measurement of a wide range of objects from various positions and can be also transported to arbitrary location. The calibration of such systems is performed by means of appropriate software which allows computation of full-energy peak efficiency in various configurations. (authors)

  11. Device for measuring the diameter of a rod for a nuclear reactor fuel element

    International Nuclear Information System (INIS)

    The device is used for the underwater determination of the diameter of a control rod of a PWR over its whole length. The guide is pivoted on the support on two pivots, which are at right angles to one another and to the longitudinal direction of the guide channel. Fitting bodies elastically sprung in the radial direction are provided for the rod on the wall of the guide channel. The second measuring cutter is supported elastically sprung in the direction of the measuring diameter. (orig./HP)

  12. Design and study of data acquisition system for pulsed γ dose measurement device

    International Nuclear Information System (INIS)

    Background: A data acquisition system for online pulsed gamma dose measurement device is designed and developed, and its performance is tested. Purpose: The data acquisition system output electric charges and input energies have a good linear relationship in both the continued and pulsed input. Methods: Experiments have been done respectively on the TDL and 'Chen Guang' accelerator. Results: The results show that the relative deviations are less than 5%. Conclusion: This data acquisition system is a new approach for online measurement of single pulsed gamma radiation dose. (authors)

  13. Device for the measurement of density distribution and cross section geometry of a particle beam

    International Nuclear Information System (INIS)

    This invention relates to a device for the measurement of relative density distribution and for the presentation of cross section geometry of accelerated proton, deuteron or other light particle beams during their application. A target is used for the measurement which can remain in the particle beam during irradiation and which absorbs only a small part of kinetic energy. The target has a thickness of at least 10 μm and is fixed within the beam tube system. It consists of a metal or carbon foil. A gas target is applicable, too

  14. Enhancement of device performance of organic solar cells by an interfacial perylene derivative layer

    KAUST Repository

    Kim, Inho

    2010-05-26

    We report that device performance of organic solar cells consisting of zinc phthalocyanine and fullerene (C60) can be enhanced by insertion of a perylene derivative interfacial layer between fullerene and bathocuproine (BCP) exciton blocking layer (EBL). The morphology of the BCP is influenced by the underlying N,N′-dihexyl-perylene-3,4,9,10-bis(dicarboximide) (PTCDI-C6), which promotes migration of the cathode metal into the BCP layer. Insertion of a PTCDI-C6 layer between fullerene and BCP layers enhances the power conversion efficiency to 2.5%, an improvement of 32% over devices without PTCDI-C6 layer. The enhancement in device performance by insertion of PTCDI-C6 is attributed to a reduction in series resistance due to promoted metal migration into BCP and optimized optical interference effects in multilayered devices. © 2010 American Chemical Society.

  15. Evaluation of the Solar Water Disinfection Method Using an Ultraviolet Measurement Device

    Science.gov (United States)

    Leung, H.

    2015-12-01

    Drinking water security is a growing problem for the population of planet Earth. According to WHO, more than 750 million people on our planet lack access to safe drinking water, resulting in approximately 502,000 diarrhoea deaths in 2012. In order to solve this problem, the Swiss water research institute, Eawag, has developed a method of solar water disinfection, called, "SODIS" The theory of SODIS is simple to understand: a clear plastic bottle filled with water is placed under full sunlight for at least 6 hours. The ultraviolet radiation kills the pathogens in the water, making the originally contaminated water safe for drinking. In order to improve this method, Helioz, an Austrian social enterprise, has created the WADI, a UV measurement device which determines when water is safe for drinking using the SODIS method. When using the WADI, the device should be placed under the sun and surrounded with bottles of water that need to be decontaminated. There is a UV sensor on the WADI, and since the bottles of water and the WADI will have equal exposure to sunlight, the WADI will be able to measure the impact of the sunlight on the contaminated water. This experiment tests the accuracy of the WADI device regarding the time interval needed for contaminated water to be disinfected. The experiment involves using the SODIS method to purify bottles of water contaminated with controlled samples of E. coli. Samples of the water are taken at different time intervals, and the E. coli levels are determined by growing the bacteria from the water samples on agar plates. Ultimately, this helps determine when the water is safe for drinking, and are compared against the WADI's measurements to test the reliability of the device.

  16. Infrared emissivity measurements of building and civil engineering materials: a new device for measuring emissivity

    OpenAIRE

    Monchau, Jean-Pierre; Marchetti, Mario; Ibos, Laurent; Dumoulin, Jean; Feuillet, Vincent; Candau, Yves

    2014-01-01

    The knowledge of the infrared emissivity of materials used in buildings and civil engineering structures is useful for two specific approaches. First, quantitative diagnosis of buildings or civil engineering infrastructures by infrared thermography requires emissivity values in the spectral bandwidth of the camera used for measurements, in order to obtain accurate surface temperatures; for instance, emissivity in the band III domain is required when using cameras with uncooled detectors (such...

  17. Measurement of force sense reproduction in the knee joint: application of a new dynamometric device

    Science.gov (United States)

    Zavieh,, Minoo Khalkhali; Amirshakeri,, Bahram; Rezasoltani,, Asghar; Talebi,, Ghadam Ali; Kalantari,, Khosro Khademi; Nedaey,, Vahab; Baghban,, Alireza Akbarzadeh

    2016-01-01

    [Purpose] The aim of this study was to determine the reliability of a newly designed dynamometric device for use in frequent force producing/reproducing tasks on the knee joint. [Subjects and Methods] In this cross-sectional study (Development & Reliability), 30 young healthy males and females (age 23.4 ± 2.48 years) were selected among students of Tabriz University of Medical Sciences by simple randomized selection. The study instrument was designed to measure any isometric contraction force exerted by the knee joint flexor/extensor muscles, known as the ipsilateral and contralateral methods. Participant knees were fixed in 60° flexion, and each participant completed the entire set of measurements twice, 72 hours apart. [Results] The findings showed a good intraclass correlation coefficient of 0.73 to 0.81 for all muscle groups. The standard error of measurement and smallest detectable difference for flexor muscle groups were 0.37 and 1.02, respectively, while the values increased to standard error of measurement=0.38 and smallest detectable difference=1.05 for extensor muscle groups. [Conclusion] The device designed could quantify the forces producing/reproducing tasks on the knee joint with a high rate of reliability, and can probably be applied for outcome measurements in proprioceptive assessment of the knee joint.

  18. New performance in harmonic analysis device generation used for magnetic fields measurements

    International Nuclear Information System (INIS)

    In particle accelerator, correcting high multipole components of magnets are of high importance for quality magnet: to get a pure quadrupole to within 10-4, we have to know the field quality to 10-5 through the 30. order. Our laboratory needed such a very sharp device to find small harmonic components of magnetic field. For harmonic analysis of magnetic field, we adopted the standard method, i.e. a rotating coil connected to a flux integrator. Nowadays, coils measuring azimuthal component of magnetic field are used. In order to obtain correct and accurate measurements, we were guided by two imperatives: first, optimisation of construction constraints and second, comparison of azimuthal and radial component measurements. With this background, this article describes both new technological solutions adopted and new performance obtained. We also discuss the most suitable geometric structure for the coils. We obtained a noiseless signal, a repeatability of 10-5 and a sensitivity up to 10-8 Weber for both types of coils. Our device is able to find and measure main component, normal and skew multipole components up to the 32. order, when simulating local defects. The magnetic axis is located within 5 μm. The central gradient is also measured and magnetic length deduced. Complementary functions of two types of coils were noticed in detecting local defects of magnetic structure. (authors)

  19. Oxygen-Purged Microfluidic Device to Enhance Cell Viability in Photopolymerized PEG Hydrogel Microparticles.

    Science.gov (United States)

    Xia, Bingzhao; Krutkramelis, Kaspars; Oakey, John

    2016-07-11

    Encapsulating cells within biocompatible materials is a widely used strategy for cell delivery and tissue engineering. While cells are commonly suspended within bulk hydrogel-forming solutions during gelation, substantial interest in the microfluidic fabrication of miniaturized cell encapsulation vehicles has more recently emerged. Here, we utilize multiphase microfluidics to encapsulate cells within photopolymerized picoliter-volume water-in-oil droplets at high production rates. The photoinitiated polymerization of polyethylene glycol diacrylate (PEGDA) is used to continuously produce solid particles from aqueous liquid drops containing cells and hydrogel forming solution. It is well understood that this photoinitiated addition reaction is inhibited by oxygen. In contrast to bulk polymerization in which ambient oxygen is rapidly and harmlessly consumed, allowing the polymerization reaction to proceed, photopolymerization within air permeable polydimethylsiloxane (PDMS) microfluidic devices allows oxygen to be replenished by diffusion as it is depleted. This sustained presence of oxygen and the consequential accumulation of peroxy radicals produce a dramatic effect upon both droplet polymerization and post-encapsulation cell viability. In this work we employ a nitrogen microjacketed microfluidic device to purge oxygen from flowing fluids during photopolymerization. By increasing the purging nitrogen pressure, oxygen concentration was attenuated, and increased post-encapsulation cell viability was achieved. A reaction-diffusion model was used to predict the cumulative intradroplet concentration of peroxy radicals, which corresponded directly to post-encapsulation cell viability. The nitrogen-jacketed microfluidic device presented here allows the droplet oxygen concentration to be finely tuned during cell encapsulation, leading to high post-encapsulation cell viability. PMID:27285343

  20. The use of an electronic portal imaging device for exit dosimetry and quality control measurements

    International Nuclear Information System (INIS)

    Purpose: To determine ways in which electronic portal imaging devices (EPIDs) could be used to (a) measure exit doses for external beam radiotherapy and (b) perform quality control checks on linear accelerators. Methods and Materials: When imaging, our fluoroscopic EPID adjusts the gain, offset, and frame acquisition time of the charge coupled device (CCD) camera automatically, to allow for the range of photon transmissions through the patient, and to optimize the signal-to-noise ratio. However, our EPID can be programmed to act as an integrating dosemeter. EPID dosemeter measurements were made for 20 MV photons, for different field sizes and thicknesses of unit density phantom material placed at varying exit surface to detector distances. These were compared with simultaneous Silicon diode exit dose measurements. Our exit dosimetry technique was verified using an anthropomorphic type phantom, and some initial measurements have been made for patients treated with irregularly shaped 20 MV x-ray fields. In this dosimetry mode, our EPID was also used to measure certain quality control parameters, x-ray field flatness, and the verification of segmented intensity modulated field prescriptions. Results: Configured for dosimetry, our EPID exhibited a highly linear response, capable of resolving individual monitor units. Exit doses could be measured to within about 3% of that measured using Silicon diodes. Field flatness was determined to within 1.5% of Farmer dosemeter measurements. Segmented intensity modulated fields can be easily verified. Conclusions: Our EPID has the versatility to assess a range of parameters pertinent to the delivery of high quality, high precision radiotherapy. When configured appropriately, it can measure exit doses in vivo, with reasonable accuracy, perform certain quick quality control checks, and analyze segmented intensity modulated treatment fields

  1. Tunable Microfluidic Devices for Hydrodynamic Fractionation of Cells and Beads: A Review

    Directory of Open Access Journals (Sweden)

    Jafar Alvankarian

    2015-11-01

    Full Text Available The adjustable microfluidic devices that have been developed for hydrodynamic-based fractionation of beads and cells are important for fast performance tunability through interaction of mechanical properties of particles in fluid flow and mechanically flexible microstructures. In this review, the research works reported on fabrication and testing of the tunable elastomeric microfluidic devices for applications such as separation, filtration, isolation, and trapping of single or bulk of microbeads or cells are discussed. Such microfluidic systems for rapid performance alteration are classified in two groups of bulk deformation of microdevices using external mechanical forces, and local deformation of microstructures using flexible membrane by pneumatic pressure. The main advantage of membrane-based tunable systems has been addressed to be the high capability of integration with other microdevice components. The stretchable devices based on bulk deformation of microstructures have in common advantage of simplicity in design and fabrication process.

  2. AEA Technologies Battery Cell By-pass Device Activation: An Update

    Science.gov (United States)

    Keys, Denney; Rao, Gopalakrishna M.; Sullivan, David; Wannemacher, Harry; Day, John H. (Technical Monitor)

    2001-01-01

    The objectives are to: (1) Verify the Performance of AEA Cell Bypass Protection Device (CBPD) under simulated EOS-Aqua/Aura flight hardware configuration; (2) Assess the Safety of the hardware under an inadvertent firing of CBPD switch, as well as the closing of CBPD switch under simulated high cell impedance; and (3) Confirm that the mode of operation of CBPD switch is the formation of a continuous low impedance path (a homogeneous low melting point alloy).

  3. Correlation between dynamic parameters and device performance of organic solar cells

    OpenAIRE

    Kniepert, Juliane

    2015-01-01

    Organic bulk heterojunction (BHJ) solar cells based on polymer:fullerene blends are a promising alternative for a low-cost solar energy conversion. Despite significant improvements of the power conversion efficiency in recent years, the fundamental working principles of these devices are yet not fully understood. In general, the current output of organic solar cells is determined by the generation of free charge carriers upon light absorption and their transport to the electrodes in competiti...

  4. The Device to Measure Currents in External Beam Transportation Lines of the DC-72 Cyclotron

    CERN Document Server

    Gulbekyan, G G; Gall, A; Kalagin, I V; Timoshenko, G N; Pachadzhiev, K K

    2002-01-01

    The present work is devoted to the development of a device to measure ion currents in external beam transportation lines of the DC-72 cyclotron, which is being created for the Cyclotron Centre of the Slovak Republic. The device is based on a Faraday cup. As possible constructive materials for the Faraday cup, Al, Cu, Fe, W and C were considered from the point of view of both the residual radiation and heating by the proton beam of the 3 kW power. Based on the calculations performed. It was suggested to use aluminium. The results of calculations of the temperature distribution in cylindrical and conic cups have been presented, both for a proton energy of 30 MeV at a beam power of 3 kW, and for a proton energy of 72 MeV at a beam power of 2.5 kW. Also presented are the results of calculation of the construction with permanent magnets that create sufficient magnetic field to eliminate the influence of secondary electrons emission on the current measurement accuracy. As a result, a sketch of the device constructi...

  5. Design and Reliability of a Novel Heel Rise Test Measuring Device for Plantarflexion Endurance

    Directory of Open Access Journals (Sweden)

    Amy D. Sman

    2014-01-01

    Full Text Available Background. Plantarflexion results from the combined action of the soleus and gastrocnemius muscles in the calf. The heel rise test is commonly used to test calf muscle endurance, function, and performance by a wide variety of professionals; however, no uniform description of the test is available. This paper aims to document the construction and reliability of a novel heel rise test device and measurement protocol that is suitable for the needs of most individuals. Methods. This device was constructed from compact and lightweight materials and is fully adjustable, enabling the testing of a wide variety of individuals. It is easy to assemble and disassemble, ensuring that it is portable for use in different settings. Findings. We tested reliability on 40 participants, finding excellent interrater reliability (ICC2,1 0.97, 95% CI: 0.94 to 0.98. Limits of agreement were less than two repetitions in 90% of cases and the Bland-Altman plot showed no bias. Interpretation. We have designed a novel, standardized, simple, and reliable device and measurement protocol for the heel rise test which can be used by researchers and clinicians in a variety of settings.

  6. A Device for Automatically Measuring and Supervising the Critical Care Patient’S Urine Output

    Directory of Open Access Journals (Sweden)

    Roemi Fernández

    2010-01-01

    Full Text Available Critical care units are equipped with commercial monitoring devices capable of sensing patients’ physiological parameters and supervising the achievement of the established therapeutic goals. This avoids human errors in this task and considerably decreases the workload of the healthcare staff. However, at present there still is a very relevant physiological parameter that is measured and supervised manually by the critical care units’ healthcare staff: urine output. This paper presents a patent-pending device capable of automatically recording and supervising the urine output of a critical care patient. A high precision scale is used to measure the weight of a commercial urine meter. On the scale’s pan there is a support frame made up of Bosch profiles that isolates the scale from force transmission from the patient’s bed, and guarantees that the urine flows properly through the urine meter input tube. The scale’s readings are sent to a PC via Bluetooth where an application supervises the achievement of the therapeutic goals. The device is currently undergoing tests at a research unit associated with the University Hospital of Getafe in Spain.

  7. Heat Transmission Coefficient Measurements in Buildings Utilizing a Heat Loss Measuring Device

    Directory of Open Access Journals (Sweden)

    Lars Schiøtt Sørensen

    2013-08-01

    Full Text Available Global energy efficiency can be obtained in two ordinary ways. One way is to improve the energy production and supply side, and the other way is, in general, to reduce the consumption of energy in society. This paper has focus on the latter and especially the consumption of energy for heating and cooling our houses. There is a huge energy-saving potential in this area for reducing both the global climate problems as well as economy challenges. Heating of buildings in Denmark accounts for approximately 40% of the entire national energy consumption. For this reason, a reduction of heat losses from building envelopes are of great importance in order to reach the Bologna CO2 emission reduction targets. Upgrading of the energy performance of buildings is a topic of huge global interest these years. Not only heating in the temperate and arctic regions are important, but also air conditioning and mechanical ventilation in the “warm countries” contribute to an enormous energy consumption and corresponding CO2 emission. In order to establish the best basis for upgrading the energy performance, it is important to make measurements of the heat losses at different places on a building facade, in order to optimize the energy performance. This paper presents a method for measuring the heat loss by utilizing a U-value meter. The U-value meter measures the heat transfer in the unit W/Km2 and has been used in several projects to upgrade the energy performance in temperate regions. The U-value meter was also utilized in an EUDP (Energy Technological Development and Demonstration Program focusing on renovation of houses from the 1960s and 1970s.

  8. A comparison of 2 white blood cell count devices to aid judicious antibiotic prescribing.

    Science.gov (United States)

    Casey, Janet R; Pichichero, Michael E

    2009-04-01

    A low or normal white blood cell (WBC) count is usually associated with viral illnesses. This study evaluated the reliability of a new point-of-care, inexpensive, WBC count device which requires only 10 microL (1 drop) of whole blood from a finger stick to an automated Cell-Dyn counter in a busy office practice setting and assessed its reliability to assist in avoiding antibiotic prescribing. A total of 120 acutely ill children and potential antibiotic recipients were studied from October 2007 to March 2008. The mean WBC count was 7.4x10(9)/L and 8.1x10( 9)/L for the new WBC device and the automated Cell-Dyn counter, respectively. The correlation between the 2 devices was high (r=.988, P=.005). A total of 88 children (73%) did not receive antibiotics and mean WBC was 7.2x10(9)/L. In all, 32 children (27%) received an antibiotic and 1 (3%) returned for a follow-up office visit for the same or a related illness. Of the 88 children with a low blood count who did not receive an antibiotic, 3 (3%) had return visit within 30 days and received an antibiotic. A simple and quick point-of-care WBC count device produces similar results as achievable with a Cell-Dyn counter for total WBCs and may assist in judicious antibiotic prescribing. PMID:19050231

  9. All-in-polymer injection molded device for single cell capture using multilevel silicon master fabrication

    DEFF Research Database (Denmark)

    Tanzi, S.; Larsen, S.T.; Matteucci, M.; Taboryski, R.

    This work demonstrates a novel all-in-polymer device for single cell capture applicable for biological recordings. The chip is injection molded and comprises a "cornered" (non planar) aperture. It has been demonstrated how cornered apertures are straightforward to mold in PDMS [1,2]. In this stud...

  10. A device to facilitate preparation of high-density neural cell cultures in MEAs.

    Science.gov (United States)

    Mok, S Y; Lim, Y M; Goh, S Y

    2009-05-15

    A device to facilitate high-density seeding of dissociated neural cells on planar multi-electrode arrays (MEAs) is presented in this paper. The device comprises a metal cover with two concentric cylinders-the outer cylinder fits tightly on to the external diameter of a MEA to hold it in place and an inner cylinder holds a central glass tube for introducing a cell suspension over the electrode area of the MEA. An O-ring is placed at the bottom of the inner cylinder and the glass tube to provide a fluid-tight seal between the glass tube and the MEA electrode surface. The volume of cell suspension in the glass tube is varied according to the desired plating density. After plating, the device can be lifted from the MEA without leaving any residue on the contact surface. The device has enabled us to increase and control the plating density of neural cell suspension with low viability, and to prepare successful primary cultures from cryopreserved neurons and glia. The cultures of cryopreserved dissociated cortical neurons that we have grown in this manner remained spontaneously active over months, exhibited stable development and similar network characteristics as reported by other researchers. PMID:19428539

  11. Digital Devices, Distraction, and Student Performance: Does In-Class Cell Phone Use Reduce Learning?

    Science.gov (United States)

    Duncan, Douglas K.; Hoekstra, Angel R.; Wilcox, Bethany R.

    2012-01-01

    The recent increase in use of digital devices such as laptop computers, iPads, and web-enabled cell phones has generated concern about how technologies affect student performance. Combining observation, survey, and interview data, this research assesses the effects of technology use on student attitudes and learning. Data were gathered in eight…

  12. Surface EMG and intra-socket force measurement to control a prosthetic device

    Science.gov (United States)

    Sanford, Joe; Patterson, Rita; Popa, Dan

    2015-06-01

    Surface electromyography (SEMG) has been shown to be a robust and reliable interaction method allowing for basic control of powered prosthetic devices. Research has shown a marked decrease in EMG-classification efficiency throughout activities of daily life due to socket shift and movement and fatigue as well as changes in degree of fit of the socket throughout the subject's lifetime. Users with the most severe levels of amputation require the most complex devices with the greatest number of degrees of freedom. Controlling complex dexterous devices with limited available inputs requires the addition of sensing and interaction modalities. However, the larger the amputation severity, the fewer viable SEMG sites are available as control inputs. Previous work reported the use of intra-socket pressure, as measured during wrist flexion and extension, and has shown that it is possible to control a powered prosthetic device with pressure sensors. In this paper, we present data correlations of SEMG data with intra-socket pressure data. Surface EMG sensors and force sensors were housed within a simulated prosthetic cuff fit to a healthy-limbed subject. EMG and intra-socket force data was collected from inside the cuff as a subject performed pre-defined grip motions with their dominant hand. Data fusion algorithms were explored and allowed a subject to use both intra-socket pressure and SEMG data as control inputs for a powered prosthetic device. This additional input modality allows for an improvement in input classification as well as information regarding socket fit through out activities of daily life.

  13. Measurement of Blood Pressure Using an Arterial Pulsimeter Equipped with a Hall Device

    Directory of Open Access Journals (Sweden)

    Jong-Gu Choi

    2011-01-01

    Full Text Available To measure precise blood pressure (BP and pulse rate without using a cuff, we have developed an arterial pulsimeter consisting of a small, portable apparatus incorporating a Hall device. Regression analysis of the pulse wave measured during testing of the arterial pulsimeter was conducted using two equations of the BP algorithm. The estimated values of BP obtained by the cuffless arterial pulsimeter over 5 s were compared with values obtained using electronic or liquid mercury BP meters. The standard deviation between the estimated values and the measured values for systolic and diastolic BP were 8.3 and 4.9, respectively, which are close to the range of values of the BP International Standard. Detailed analysis of the pulse wave measured by the cuffless radial artery pulsimeter by detecting changes in the magnetic field can be used to develop a new diagnostic algorithm for BP, which can be applied to new medical apparatus such as the radial artery pulsimeter.

  14. The boron concentration measurement by the prompt gamma-ray analysis device at JRR-4

    International Nuclear Information System (INIS)

    In determining the dose for BNCT, it is important to measure the boron concentration in blood as well as the thermal neutron fluence. To attain an accurate measurement of the boron concentration in the whole blood at about 30 ppm, the Prompt Gamma-ray Analysis (PGA) is adopted to enable the measurement with a high degree of accuracy in short time, since the chemical analysis technique has some difficulties on it. In order to install the PGA device in a swimming pool type research reactor JRR-4, the super-mirror for obtaining the necessary neutron flux in the space over the pool surface was perpendicularly placed, because the reactor had no horizontal experiment tube for this kind of use. As the accurate measurement of the boron concentration in whole blood using PGA is enabled herewith, the first medical irradiation for BNCT at JRR-4 was carried out on October 25, 1999. (author)

  15. Optomechanical measurement of photon spin angular momentum and optical torque in integrated photonic devices

    CERN Document Server

    He, Li; Li, Mo

    2016-01-01

    Photons carry linear momentum, and spin angular momentum when circularly or elliptically polarized. During light-matter interaction, transfer of linear momentum leads to optical forces, while angular momentum transfer induces optical torque. Optical forces including radiation pressure and gradient forces have long been utilized in optical tweezers and laser cooling. In nanophotonic devices optical forces can be significantly enhanced, leading to unprecedented optomechanical effects in both classical and quantum regimes. In contrast, to date, the angular momentum of light and the optical torque effect remain unexplored in integrated photonics. Here, we demonstrate the measurement of the spin angular momentum of photons propagating in a birefringent waveguide and the use of optical torque to actuate rotational motion of an optomechanical device. We show that the sign and magnitude of the optical torque are determined by the photon polarization states that are synthesized on the chip. Our study reveals the mecha...

  16. Device to measure the position of a movable organ with regard to a fixed equipment

    International Nuclear Information System (INIS)

    The present device measures the displacement of control rods in nuclear reactors. Whatever, the invention can be applied in all the cases when it is necessary to know with precision the position of a movable equipment in a given direction, even in a hostile environment and without it being too important. The device comprises a magnetic reference point carried by the movable organ, at least one row of magnetic sensors disposed at regular intervals along the said direction; the dimensions of the magnetic reference mark, of the sensors and of the intervals are such that at least one sensor is excited whatever the position of the magnetic reference may be, each sensor comprising an excitation element, a lecture element, and an interconnection circuit of the said sensor

  17. Measurements of Charge Transfer Efficiency in a Proton-irradiated Swept Charge Device

    CERN Document Server

    YuSa, Wang; XiaoYan, Liu; WeiWei, Cui; YuPeng, Xu; ChengKui, Li; MaoShun, Li; DaWei, Han; TianXiang, Chen; Jia, Huo; Juan, Wang; Wei, Li; Wei, Hu; Yi, Zhang; Bo, Lu; GuoHe, Yin; Yue, Zhu; ZiLiang, Zhang

    2013-01-01

    Charge Coupled Devices (CCDs) have been successfully used in several low energy X-ray astronomical satellite over the past two decades. Their high energy resolution and high spatial resolution make them an perfect tool for low energy astronomy, such as formation of galaxy clusters and environment of black holes. The Low Energy X-ray Telescope (LE) group is developing Swept Charge Device (SCD) for the Hard X-ray Modulation Telescope (HXMT) satellite. SCD is a special low energy X-ray CCD, which could be read out a thousand times faster than traditional CCDs, simultaneously keeping excellent energy resolution. A test method for measuring the charge transfer efficiency (CTE) of a prototype SCD has been set up. Studies of the charge transfer inefficiency (CTI) have been performed at a temperature range of operation, with a proton-irradiated SCD.

  18. Sub-10 nm nano-gap device for single-cluster transport measurements

    International Nuclear Information System (INIS)

    We present a versatile procedure for the fabrication of single electron transistor (SET) devices with nanometer-sized clusters and embedded back gate electrode. The process uses sputtering gas-aggregation for the growth of clusters and e-beam lithography with double angle shadow-edge deposition to obtain electrodes separated by nano-gaps with width below 10 nm. The nano-gap width is easily controlled only by geometrical factors such as deposited thin film thickness and evaporation angles. The usefulness of this technique is demonstrated by measuring the SET behavior of a device with a 4 nm cobalt cluster embedded in alumina, where the Coulomb blockade and incremental cluster charging can be readily identified without resorting to the differential conductivity

  19. Plug-and-play measurement-device-independent quantum key distribution

    Science.gov (United States)

    Choi, Yujun; Kwon, Osung; Woo, Minki; Oh, Kyunghwan; Han, Sang-Wook; Kim, Yong-Su; Moon, Sung

    2016-03-01

    Quantum key distribution (QKD) guarantees unconditional communication security based on the laws of quantum physics. However, practical QKD suffers from a number of quantum hackings due to the device imperfections. From the security standpoint, measurement-device-independent quantum key distribution (MDI-QKD) is in the limelight since it eliminates all the possible loopholes in detection. Due to active control units for mode matching between the photons from remote parties, however, the implementation of MDI-QKD is highly impractical. In this paper, we propose a method to resolve the mode matching problem while minimizing the use of active control units. By introducing the plug-and-play (P&P) concept into MDI-QKD, the indistinguishability in spectral and polarization modes between photons can naturally be guaranteed. We show the feasibility of P&P MDI-QKD with a proof-of-principle experiment.

  20. Microfluidic gradient device for studying mesothelial cell migration and the effect of chronic carbon nanotube exposure

    International Nuclear Information System (INIS)

    Cell migration is one of the crucial steps in many physiological and pathological processes, including cancer development. Our recent studies have shown that carbon nanotubes (CNTs), similarly to asbestos, can induce accelerated cell growth and invasiveness that contribute to their mesothelioma pathogenicity. Malignant mesothelioma is a very aggressive tumor that develops from cells of the mesothelium, and is most commonly caused by exposure to asbestos. CNTs have a similar structure and mode of exposure to asbestos. This has raised a concern regarding the potential carcinogenicity of CNTs, especially in the pleural area which is a key target for asbestos-related diseases. In this paper, a static microfluidic gradient device was applied to study the migration of human pleural mesothelial cells which had been through a long-term exposure (4 months) to subcytotoxic concentration (0.02 µg cm−2) of single-walled CNTs (SWCNTs). Multiple migration signatures of these cells were investigated using the microfluidic gradient device for the first time. During the migration study, we observed that cell morphologies changed from flattened shapes to spindle shapes prior to their migration after their sensing of the chemical gradient. The migration of chronically SWCNT-exposed mesothelial cells was evaluated under different fetal bovine serum (FBS) concentration gradients, and the migration speeds and number of migrating cells were extracted and compared. The results showed that chronically SWCNT-exposed mesothelial cells are more sensitive to the gradient compared to non-SWCNT-exposed cells. The method described here allows simultaneous detection of cell morphology and migration under chemical gradient conditions, and also allows for real-time monitoring of cell motility that resembles in vivo cell migration. This platform would be much needed for supporting the development of more physiologically relevant cell models for better assessment and characterization of the

  1. Microfluidic gradient device for studying mesothelial cell migration and the effect of chronic carbon nanotube exposure

    Science.gov (United States)

    Zhang, Hanyuan; Lohcharoenkal, Warangkana; Sun, Jianbo; Li, Xiang; Wang, Liying; Wu, Nianqiang; Rojanasakul, Yon; Liu, Yuxin

    2016-01-01

    Cell migration is one of the crucial steps in many physiological and pathological processes, including cancer development. Our recent studies have shown that carbon nanotubes (CNTs), similarly to asbestos, can induce accelerated cell growth and invasiveness that contribute to their mesothelioma pathogenicity. Malignant mesothelioma is a very aggressive tumor that develops from cells of the mesothelium, and is most commonly caused by exposure to asbestos. CNTs have a similar structure and mode of exposure to asbestos. This has raised a concern regarding the potential carcinogenicity of CNTs, especially in the pleural area which is a key target for asbestos-related diseases. In this paper, a static microfluidic gradient device was applied to study the migration of human pleural mesothelial cells which had been through a long-term exposure (4 months) to subcytotoxic concentration (0.02 μg cm−2) of single-walled CNTs (SWCNTs). Multiple migration signatures of these cells were investigated using the microfluidic gradient device for the first time. During the migration study, we observed that cell morphologies changed from flattened shapes to spindle shapes prior to their migration after their sensing of the chemical gradient. The migration of chronically SWCNT-exposed mesothelial cells was evaluated under different fetal bovine serum (FBS) concentration gradients, and the migration speeds and number of migrating cells were extracted and compared. The results showed that chronically SWCNT-exposed mesothelial cells are more sensitive to the gradient compared to non-SWCNT-exposed cells. The method described here allows simultaneous detection of cell morphology and migration under chemical gradient conditions, and also allows for real-time monitoring of cell motility that resembles in vivo cell migration. This platform would be much needed for supporting the development of more physiologically relevant cell models for better assessment and characterization of the

  2. The IsoStretcher: An isotropic cell stretch device to study mechanical biosensor pathways in living cells.

    Science.gov (United States)

    Schürmann, S; Wagner, S; Herlitze, S; Fischer, C; Gumbrecht, S; Wirth-Hücking, A; Prölß, G; Lautscham, L A; Fabry, B; Goldmann, W H; Nikolova-Krstevski, V; Martinac, B; Friedrich, O

    2016-07-15

    Mechanosensation in many organs (e.g. lungs, heart, gut) is mediated by biosensors (like mechanosensitive ion channels), which convert mechanical stimuli into electrical and/or biochemical signals. To study those pathways, technical devices are needed that apply strain profiles to cells, and ideally allow simultaneous live-cell microscopy analysis. Strain profiles in organs can be complex and multiaxial, e.g. in hollow organs. Most devices in mechanobiology apply longitudinal uniaxial stretch to adhered cells using elastomeric membranes to study mechanical biosensors. Recent approaches in biomedical engineering have employed intelligent systems to apply biaxial or multiaxial stretch to cells. Here, we present an isotropic cell stretch system (IsoStretcher) that overcomes some previous limitations. Our system uses a rotational swivel mechanism that translates into a radial displacement of hooks attached to small circular silicone membranes. Isotropicity and focus stability are demonstrated with fluorescent beads, and transmission efficiency of elastomer membrane stretch to cellular area change in HeLa/HEK cells. Applying our system to lamin-A overexpressing fibrosarcoma cells, we found a markedly reduced stretch of cell area, indicative of a stiffer cytoskeleton. We also investigated stretch-activated Ca(2+) entry into atrial HL-1 myocytes. 10% isotropic stretch induced robust oscillating increases in intracellular Fluo-4 Ca(2+) fluorescence. Store-operated Ca(2+) entry was not detected in these cells. The Isostretcher provides a useful versatile tool for mechanobiology. PMID:26991603

  3. CALIBRATION OF DEVICES FOR MEASURING ELEMENTS OF MICRO-ELECTRONIC STRUCTURES

    Directory of Open Access Journals (Sweden)

    G. Trapashko

    2012-01-01

    Full Text Available Development of microelectronics requires solution of the problem ensuring unity of linear measurements in a submicron range. The problem can be solved on the condition that calibration of measuring devices shall be made in accordance with reference samples that is a short length scale.While making calibration of measuring equipment with the help of a reference measure it is important to investigate components of the method accuracy and their influence on measuring results. The paper considers methodical errors which are specific for methods of optical and atomic force microscopy. Calibration results of an optical measuring microscope are given in the paper. The paper reveals that an additive error depends on parameters of a material and the form of measured elements for an optical measuring microscope. The methodical error of atomic force microscopes is predicated on the probe point shape. The paper considers a short length scale used for calibration of optical and atomic force microscopes. Recommendations for users of the measuring equipment are formulated in the paper.

  4. Design of energy spectrum device for radon measuring with electrostatic collection method

    International Nuclear Information System (INIS)

    Background: This research is to take energy spectrum of α particle into consideration in the measurement of radon. Purpose: We aim to find the influence factors of screening particle energy. during the process of detector design. Methods: Based on the electrostatic collection radon measurement method, in order to study the influence factors of the measurement such as aluminum foil and air layer, the reasonable radiation source and geometric model are abstracted and calculated with Geant4 software. Results: The best ranges of aluminum foil thickness and air layer thickness are obtained by analyzing their relationship with a energy, the Full Width at Half Maximum (FWHM), the energy resolution, the distance of peaks and the peaks screening power. Conclusion: With the results adopted above, the energy spectrum device is fabricated. Based on the α energy spectrum sampled in a radon chamber, the validity of this design has been proved. It provides a set of reliable data for the design of radon measuring device with electrostatic collection method. (authors)

  5. Calibration Of X-Ray Imaging Devices For Accurate Intensity Measurement

    International Nuclear Information System (INIS)

    National Security Technologies (NSTec) has developed calibration procedures for X-ray imaging systems. The X-ray sources that are used for calibration are both diode type and diode/fluorescer combinations. Calibrating the X-ray detectors is key to accurate calibration of the X-ray sources. Both energy dispersive detectors and photodiodes measuring total flux were used. We have developed calibration techniques for the detectors using radioactive sources that are traceable to the National Institute of Standards and Technology (NIST). The German synchrotron at Physikalische Technische Bundestalt (PTB) is used to calibrate silicon photodiodes over the energy range from 50 eV to 60 keV. The measurements on X-ray cameras made using the NSTec X-ray sources have included quantum efficiency averaged over all pixels, camera counts per photon per pixel, and response variation across the sensor. The instrumentation required to accomplish the calibrations is described. X-ray energies ranged from 720 eV to 22.7 keV. The X-ray sources produce narrow energy bands, allowing us to determine the properties as a function of X-ray energy. The calibrations were done for several types of imaging devices. There were back illuminated and front illuminated CCD (charge coupled device) sensors, and a CID (charge injection device) type camera. The CCD and CID camera types differ significantly in some of their properties that affect the accuracy of X-ray intensity measurements. All cameras discussed here are silicon based. The measurements of quantum efficiency variation with X-ray energy are compared to models for the sensor structure. Cameras that are not back-thinned are compared to those that are.

  6. CALIBRATION OF X-RAY IMAGING DEVICES FOR ACCURATE INTENSITY MEASUREMENT

    Energy Technology Data Exchange (ETDEWEB)

    Haugh, M J; Charest, M R; Ross, P W; Lee, J J; Schneider, M B; Palmer, N E; Teruya, A T

    2012-02-16

    National Security Technologies (NSTec) has developed calibration procedures for X-ray imaging systems. The X-ray sources that are used for calibration are both diode type and diode/fluorescer combinations. Calibrating the X-ray detectors is key to accurate calibration of the X-ray sources. Both energy dispersive detectors and photodiodes measuring total flux were used. We have developed calibration techniques for the detectors using radioactive sources that are traceable to the National Institute of Standards and Technology (NIST). The German synchrotron at Physikalische Technische Bundestalt (PTB) is used to calibrate silicon photodiodes over the energy range from 50 eV to 60 keV. The measurements on X-ray cameras made using the NSTec X-ray sources have included quantum efficiency averaged over all pixels, camera counts per photon per pixel, and response variation across the sensor. The instrumentation required to accomplish the calibrations is described. X-ray energies ranged from 720 eV to 22.7 keV. The X-ray sources produce narrow energy bands, allowing us to determine the properties as a function of X-ray energy. The calibrations were done for several types of imaging devices. There were back illuminated and front illuminated CCD (charge coupled device) sensors, and a CID (charge injection device) type camera. The CCD and CID camera types differ significantly in some of their properties that affect the accuracy of X-ray intensity measurements. All cameras discussed here are silicon based. The measurements of quantum efficiency variation with X-ray energy are compared to models for the sensor structure. Cameras that are not back-thinned are compared to those that are.

  7. Passive safety device and internal short tested method for energy storage cells and systems

    Science.gov (United States)

    Keyser, Matthew; Darcy, Eric; Long, Dirk; Pesaran, Ahmad

    2015-09-22

    A passive safety device for an energy storage cell for positioning between two electrically conductive layers of the energy storage cell. The safety device also comprising a separator and a non-conductive layer. A first electrically conductive material is provided on the non-conductive layer. A first opening is formed through the separator between the first electrically conductive material and one of the electrically conductive layers of the energy storage device. A second electrically conductive material is provided adjacent the first electrically conductive material on the non-conductive layer, wherein a space is formed on the non-conductive layer between the first and second electrically conductive materials. A second opening is formed through the non-conductive layer between the second electrically conductive material and another of the electrically conductive layers of the energy storage device. The first and second electrically conductive materials combine and exit at least partially through the first and second openings to connect the two electrically conductive layers of the energy storage device at a predetermined temperature.

  8. Resistive switching behavior of reduced graphene oxide memory cells for low power nonvolatile device application

    Science.gov (United States)

    Pradhan, Sangram K.; Xiao, Bo; Mishra, Saswat; Killam, Alex; Pradhan, Aswini K.

    2016-05-01

    Graphene Oxide (GO) based low cost flexible electronics and memory cell have recently attracted more attention for the fabrication of emerging electronic devices. As a suitable candidate for resistive random access memory technology, reduced graphene oxide (RGO) can be widely used for non-volatile switching memory applications because of its large surface area, excellent scalability, retention, and endurance properties. We demonstrated that the fabricated metal/RGO/metal memory device exhibited excellent switching characteristics, with on/off ratio of two orders of magnitude and operated threshold switching voltage of less than 1 V. The studies on different cell diameter, thickness, scan voltages and period of time corroborate the reliability of the device as resistive random access memory. The microscopic origin of switching operation is governed by the establishment of conducting filaments due to the interface amorphous layer rupturing and the movement of oxygen in the GO layer. This interesting experimental finding indicates that device made up of thermally reduced GO shows more reliability for its use in next generation electronics devices.

  9. Designing and modeling a centrifugal microfluidic device to separate target blood cells

    International Nuclear Information System (INIS)

    The objective of this study is to design a novel and efficient portable lab-on-a-CD (LOCD) microfluidic device for separation of specific cells (target cells) using magnetic beads. In this study the results are shown for neutrophils as target cells. However, other kinds of target cells can be separated in a similar approach. The designed microfluidics can be utilized as a point of care system for neutrophil detection. This microfluidic system employs centrifugal and magnetic forces for separation. After model validation by the experimental data in the literature (that may be used as a design tool for developing centrifugo-magnetophoretic devices), two models are presented for separation of target cells using magnetic beads. The first model consists of one container in the inlet section and two containers in the outlets. Initially, the inlet container is filled with diluted blood sample which is a mixture of red blood cells (RBCs) plus neutrophils which are attached to Magnetic beads. It is shown that by using centrifugal and magnetic forces, this model can separate all neutrophils with recovery factor of ∼100%. In the second model, due to excess of magnetic beads in usual experimental analysis (to ensure that all target cells are attached to them) the geometry is improved by adding a third outlet for these free magnetic beads. It is shown that at angular velocity of 45 rad s−1, recovery factor of 100% is achievable for RBCs, free magnetic beads and neutrophils as target cells. (paper)

  10. Designing and modeling a centrifugal microfluidic device to separate target blood cells

    Science.gov (United States)

    Shamloo, Amir; Selahi, AmirAli; Madadelahi, Masoud

    2016-03-01

    The objective of this study is to design a novel and efficient portable lab-on-a-CD (LOCD) microfluidic device for separation of specific cells (target cells) using magnetic beads. In this study the results are shown for neutrophils as target cells. However, other kinds of target cells can be separated in a similar approach. The designed microfluidics can be utilized as a point of care system for neutrophil detection. This microfluidic system employs centrifugal and magnetic forces for separation. After model validation by the experimental data in the literature (that may be used as a design tool for developing centrifugo-magnetophoretic devices), two models are presented for separation of target cells using magnetic beads. The first model consists of one container in the inlet section and two containers in the outlets. Initially, the inlet container is filled with diluted blood sample which is a mixture of red blood cells (RBCs) plus neutrophils which are attached to Magnetic beads. It is shown that by using centrifugal and magnetic forces, this model can separate all neutrophils with recovery factor of ~100%. In the second model, due to excess of magnetic beads in usual experimental analysis (to ensure that all target cells are attached to them) the geometry is improved by adding a third outlet for these free magnetic beads. It is shown that at angular velocity of 45 rad s-1, recovery factor of 100% is achievable for RBCs, free magnetic beads and neutrophils as target cells.

  11. External circuit integration with electromagnetic particle in cell modeling of plasma focus devices

    International Nuclear Information System (INIS)

    The pinch performance of a plasma focus (PF) device is sensitive to the physical conditions of the breakdown phase. It is therefore essential to model and study the initial phase in order to optimize device performance. An external circuit is self consistently coupled to the electromagnetic particle in cell code to model the breakdown and initial lift phase of the United Nations University/International Centre for Theoretical Physics (UNU-ICTP) plasma focus device. Gas breakdown during the breakdown phase is simulated successfully, following a drop in the applied voltage across the device and a concurrent substantial rise in the circuit current. As a result, the plasma becomes magnetized, with the growing value of the magnetic field over time leading to the gradual lift off of the well formed current sheath into the axial acceleration phase. This lifting off, with simultaneous outward sheath motion along the anode and vertical cathode, and the strong magnetic fields in the current sheath region, was demonstrated in this work, and hence validates our method of coupling the external circuit to PF devices. Our method produces voltage waveforms that are qualitatively similar to the observed experimental voltage profiles of the UNU-ICTP device. Values of the mean electron energy before and after voltage breakdown turned out to be different, with the values after breakdown being much lower. In both cases, the electron energy density function turned out to be non-Maxwellian

  12. Efficiency improvement in thin-film solar cell devices with oxygen-containing absorber layer

    International Nuclear Information System (INIS)

    The CdTe/CdS solar cell devices were grown using a dry process consisting of sputtering for the transparent conducting oxide and CdS window layers, and close-space sublimation for CdTe absorber layer. These devices were back contacted using Mo/Sb2Te3 sputtered layers following the CdCl2 activation process carried out in air. It was shown that when oxygen is intentionally introduced in the CdTe layer during its growth, this leads to a significant improvement in all the device parameters yielding an efficiency of 14% compared to 11.5% for devices fabricated in the same conditions but without intentional oxygen incorporation in CdTe. The data obtained were not altered following a light soaking. The devices were investigated by quantitative secondary ion mass spectrometry, which allowed insight into the distribution and amount of oxygen and chlorine within the entire device structure. Both impurities showed an increased concentration throughout the CdTe absorber layer

  13. A hybrid microfluidic-vacuum device for direct interfacing with conventional cell culture methods

    Directory of Open Access Journals (Sweden)

    Monuki Edwin S

    2007-09-01

    Full Text Available Abstract Background Microfluidics is an enabling technology with a number of advantages over traditional tissue culture methods when precise control of cellular microenvironment is required. However, there are a number of practical and technical limitations that impede wider implementation in routine biomedical research. Specialized equipment and protocols required for fabrication and setting up microfluidic experiments present hurdles for routine use by most biology laboratories. Results We have developed and validated a novel microfluidic device that can directly interface with conventional tissue culture methods to generate and maintain controlled soluble environments in a Petri dish. It incorporates separate sets of fluidic channels and vacuum networks on a single device that allows reversible application of microfluidic gradients onto wet cell culture surfaces. Stable, precise concentration gradients of soluble factors were generated using simple microfluidic channels that were attached to a perfusion system. We successfully demonstrated real-time optical live/dead cell imaging of neural stem cells exposed to a hydrogen peroxide gradient and chemotaxis of metastatic breast cancer cells in a growth factor gradient. Conclusion This paper describes the design and application of a versatile microfluidic device that can directly interface with conventional cell culture methods. This platform provides a simple yet versatile tool for incorporating the advantages of a microfluidic approach to biological assays without changing established tissue culture protocols.

  14. A High Power-Density Mediator-Free Microfluidic Biophotovoltaic Device for Cyanobacterial Cells

    CERN Document Server

    Bombelli, Paolo; Herling, Therese W; Howe, Christopher J; Knowles, Tuomas P J

    2014-01-01

    Biophotovoltaics has emerged as a promising technology for generating renewable energy since it relies on living organisms as inexpensive, self-repairing and readily available catalysts to produce electricity from an abundant resource - sunlight. The efficiency of biophotovoltaic cells, however, has remained significantly lower than that achievable through synthetic materials. Here, we devise a platform to harness the large power densities afforded by miniaturised geometries. To this effect, we have developed a soft-lithography approach for the fabrication of microfluidic biophotovoltaic devices that do not require membranes or mediators. Synechocystis sp. PCC 6803 cells were injected and allowed to settle on the anode, permitting the physical proximity between cells and electrode required for mediator-free operation. We demonstrate power densities of above 100 mW/m2 for a chlorophyll concentration of 100 {\\mu}M under white light, a high value for biophotovoltaic devices without extrinsic supply of additional...

  15. Standard test method for calibration of surface/stress measuring devices

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    1997-01-01

    Return to Contents page 1.1 This test method covers calibration or verification of calibration, or both, of surface-stress measuring devices used to measure stress in annealed and heat-strengthened or tempered glass using polariscopic or refractometry based principles. 1.2 This test method is nondestructive. 1.3 This test method uses transmitted light, and therefore, is applicable to light-transmitting glasses. 1.4 This test method is not applicable to chemically tempered glass. 1.5 Using the procedure described, surface stresses can be measured only on the “tin” side of float glass. 1.6 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

  16. Development of an automatic sampling device for the continuous measurement of atmospheric carbonyls compounds

    International Nuclear Information System (INIS)

    Two sampling strategies were studied to develop an automatic instrument for the continuous measurement of atmospheric carbonyl compounds. Because of its specificity towards carbonyls compounds, sampling by using a transfer of gaseous phase in a liquid phase associated with a simultaneous chemical derivatization of the trapped compounds was first studied. However, this method do not allow a quantitative sampling of all studied carbonyl compounds, nor a continuous measurement in the field. To overcome the difficulties, a second strategy was investigated: the cryogenic adsorption onto solid adsorbent followed by thermodesorption and a direct analysis by GC/MS. Collection efficiency using different solid adsorbents was found greater than 95% for carbonyl compounds consisting of 1 to 7 carbons. This work is a successful first step towards the realization of the automatic sampling device for a continuous measurement of atmospheric carbonyls compounds. (author)

  17. Design and testing of an innovative measurement device for tyre-road contact forces

    Science.gov (United States)

    Cheli, F.; Braghin, F.; Brusarosco, M.; Mancosu, F.; Sabbioni, E.

    2011-08-01

    The measurement of tyre-road contact forces is the first step towards the development of new control systems for improving vehicle safety and performances. Tyre-road contact forces measurement systems are very expensive and significantly modify the unsprung masses of the vehicle as well as the rotational inertia of the tyres. Thus, vehicle dynamics results are significantly affected. As a consequence, the measured contact forces do not correspond to the contact forces under real working conditions. A new low-cost tyre-road contact forces measurement system is proposed in this paper that can be applied to passenger cars. Its working principle is based on the measurement of three deformations of the wheel rim through strain gauges. The tyre-rim assembly is thus turned into a sensor for tyre-road contact forces. The influence of the strain gauges position onto the measurement results has been assessed through finite element simulations and experimental tests. It has been proven that, for a large variety of rims, the strain gauge position that leads to high signal-to-noise ratios is almost the same. A dynamic calibration procedure has been developed in order to allow the reconstruction of contact force and torque components once per wheel turn. The capability of the developed device to correctly estimate tyre-road contact forces has been assessed, in a first stage, through indoor laboratory experimental test on an MTS Flat-Trac ® testing machine. Results show that the implemented measuring system allows to reconstruct contact forces once per wheel turn with a precision that is comparable to that of existing high-cost measurement systems. Subsequently, outdoor tests with a vehicle having all four wheels equipped with the developed measuring device have also been performed. Reliability of the measurements provided by the developed sensor has been assessed by comparing the global measured longitudinal/lateral forces and the product of the measured longitudinal

  18. Phase-Reference-Free Experiment of Measurement-Device-Independent Quantum Key Distribution.

    Science.gov (United States)

    Wang, Chao; Song, Xiao-Tian; Yin, Zhen-Qiang; Wang, Shuang; Chen, Wei; Zhang, Chun-Mei; Guo, Guang-Can; Han, Zheng-Fu

    2015-10-16

    Measurement-device-independent quantum key distribution (MDI QKD) is a substantial step toward practical information-theoretic security for key sharing between remote legitimate users (Alice and Bob). As with other standard device-dependent quantum key distribution protocols, such as BB84, MDI QKD assumes that the reference frames have been shared between Alice and Bob. In practice, a nontrivial alignment procedure is often necessary, which requires system resources and may significantly reduce the secure key generation rate. Here, we propose a phase-coding reference-frame-independent MDI QKD scheme that requires no phase alignment between the interferometers of two distant legitimate parties. As a demonstration, a proof-of-principle experiment using Faraday-Michelson interferometers is presented. The experimental system worked at 1 MHz, and an average secure key rate of 8.309 bps was obtained at a fiber length of 20 km between Alice and Bob. The system can maintain a positive key generation rate without phase compensation under normal conditions. The results exhibit the feasibility of our system for use in mature MDI QKD devices and its value for network scenarios. PMID:26550855

  19. Reply to: Discrete-variable measurement-device-independent quantum key distribution suitable for metropolitan networks

    CERN Document Server

    Pirandola, Stefano; Spedalieri, Gaetana; Weedbrook, Christian; Braunstein, Samuel L; Lloyd, Seth; Gehring, Tobias; Jacobsen, Christian S; Andersen, Ulrik L

    2015-01-01

    In a recent comment, Xu et al. claimed that discrete-variable (DV) measurement-device-independent (MDI) quantum key distribution (QKD) would compete with its continuous-variable (CV) counterpart at metropolitan distances. Actually, Xu et al.'s analysis supports the opposite by showing that the experimental rate of our CV protocol (achieved with practical room-temperature devices) remains one order of magnitude higher than their purely-numerical and over-optimistic extrapolation for qubits, based on nearly-ideal parameters and cryogenic detectors (clearly unsuitable for the construction of a realistic, cheap and scalable high-rate network, e.g., including mobile devices). The experimental rate of our protocol (bits per relay use) is confirmed to be two-three orders of magnitude higher than the rate of any realistic simulation of practical DV-MDI-QKD over short-medium distances. Of course this does not mean that DV-MDI-QKD networks should not be investigated or built, but increasing their rate is a non-trivial ...

  20. Understanding and assessing the impact of treatment in diabetes: the Treatment-Related Impact Measures for Diabetes and Devices (TRIM-Diabetes and TRIM-Diabetes Device

    Directory of Open Access Journals (Sweden)

    Lessard Suzanne

    2009-09-01

    Full Text Available Abstract Purpose Diabetes is a debilitating illness requiring lifelong management. Treatments can be varied in terms of mode of administration as well as type of agent. Unfortunately, most patient reported outcome measures currently available to assess the impact of treatment are specific to diabetes type, treatment modality or delivery systems and are designed to be either a HRQoL or treatment satisfaction measure. To address these gaps, the Treatment Related Impact Measure-Diabetes and Device measures were developed. This paper presents the item development and validation of the TRIM Diabetes/Device. Methods Patient interviews were conducted to collect the patient perspective and ensure high content validity. Interviews were hand coded and qualitatively analyzed to identify common themes. A conceptual model of the impact of diabetes medication was developed and preliminary items for the TRIM-Diabetes/Device were generated and cognitively debriefed. Validation data was collected via an on-line survey and analyzed according to an a priori statistical analysis plan to validate the overall score as well as each domain. Item level criteria were used to reduce the preliminary item pool. Next, factor analysis to identify structural domains was performed. Reliability and validity testing was then performed. Results One hundred and five patients were interviewed in focus groups, individual interviews and for cognitive debriefing. Five hundred seven patients participated in the validation study. Factor analysis identified seven domains: Treatment Burden, Daily Life; Diabetes Management; Psychological Health; Compliance and Device Function and Bother. Internal consistency reliability coefficients of the TRIM-Diabetes/Device ranged from 0.80 and 0.94. Test-retest reliability of the TRIM-Diabetes/Device ranged from 0.71 to 0.89. All convergent and known groups validity hypotheses were met for the TRIM-Diabetes/Device total scores and sub-scales. Conclusion

  1. Lessons from wet gas flow metering systems using differential measurements devices: Testing and flow modelling results

    Energy Technology Data Exchange (ETDEWEB)

    Cazin, J.; Couput, J.P.; Dudezert, C. et al

    2005-07-01

    A significant number of wet gas meters used for high GVF and very high GVF are based on differential pressure measurements. Recent high pressure tests performed on a variety of different DP devices on different flow loops are presented. Application of existing correlations is discussed for several DP devices including Venturi meters. For Venturi meters, deviations vary from 9% when using the Murdock correlation to less than 3 % with physical based models. The use of DP system in a large domain of conditions (Water Liquid Ratio) especially for liquid estimation will require information on the WLR This obviously raises the question of the gas and liquid flow metering accuracy in wet gas meters and highlight needs to understand AP systems behaviour in wet gas flows (annular / mist / annular mist). As an example, experimental results obtained on the influence of liquid film characteristics on a Venturi meter are presented. Visualizations of the film upstream and inside the Venturi meter are shown. They are completed by film characterization. The AP measurements indicate that for a same Lockhart Martinelli parameter, the characteristics of the two phase flow have a major influence on the correlation coefficient. A 1D model is defined and the results are compared with the experiments. These results indicate that the flow regime influences the AP measurements and that a better modelling of the flow phenomena is needed even for allocation purposes. Based on that, lessons and way forward in wet gas metering systems improvement for allocation and well metering are discussed and proposed. (author) (tk)

  2. Measurement of radon, radon daughters and thoron concentrations by multi-detector devices. No. E/12

    International Nuclear Information System (INIS)

    There is a growing interest in collection of data concerning human exposures to naturally occurring alpha-emitting radionuclides (e.g. in mines, dwellings, building materials, industrial wastes, coal fuel cycle, water supply, soil, plants, etc.). Most of such studies are incomplete for the following reasons: in radon measurements the contribution of thoron is generally neglected, the determination of equilibrium factor is complicated or not possible at all, short- and long-term concentration fluctuations cause difficulties in obtaining representative mean values, the plate-out effect is generally not taken into account. A variety of simple methods were studied that could be used to overcome some of these difficulties by using cups equipped with two or more alpha-sensitive nuclear track detectors. A theoretical foundation of the quantitative measurements with such devices is presented. Experimental data are reported on radon, radon daughters and thoron concentrations measured by multi-detector devices in cave soil gas and in air of Hungarian dwellings. (author)

  3. Influence of the Type of Measuring Device in Determining the Static Modulus of Elasticity of Concrete

    Directory of Open Access Journals (Sweden)

    Suélio da Silva Araújo

    2013-01-01

    Full Text Available This paper presents a comparative analysis of the results obtained in static modulus of elasticity tests of plain concrete cylindrical specimens. The purpose of this study is to identify and evaluate the influence of several factors involved in modulus of elasticity tests such as the strain measurement device used (dial indicators, electrical surface bonded strain gages, externally fixed strain gages and linear variation displacement transducer - LVDT, the type of concrete (Class C30 and Class C60 and cylindrical specimen size (100 mm x 200 mm and 150 mm x 300 mm. The modulus tests were done in two different laboratories in the Goiânia, GO region and were performed according to code ABNT NBR 8522:2008, which describes the initial tangent modulus test, characterized by strains measured at tension values of 0.5 MPa and 30% of the ultimate load. One hundred and sixty specimens were tested with statistically satisfactory results. It was concluded that the type of strain measurement device greatly influenced the modulus of elasticity results. Tests in specimens 100 mm x 200 mm showed highest statistical variation.

  4. Using complete measurement statistics for optimal device-independent randomness evaluation

    OpenAIRE

    Nieto-Silleras, Olmo; Pironio, Stefano; Silman, Jonathan

    2014-01-01

    The majority of recent works investigating the link between non-locality and randomness, e.g. in the context of device-independent cryptography, do so with respect to some specific Bell inequality, usually the CHSH inequality. However, the joint probabilities characterizing the measurement outcomes of a Bell test are richer than just the degree of violation of a single Bell inequality. In this work we show how to take this extra information into account in a systematic manner in order to opti...

  5. Quantum transport measurement of few-layer WTe2 field effect devices

    Science.gov (United States)

    Chen, Jianhao; Liu, Xin; Tian, Shibing; Zhang, Chenglong; Jia, Shuang

    2015-03-01

    We have performed systematic quantum transport measurement on field effect devices fabricated from few-layer WTe2 single crystals. We found that the magnetoresistance of few-layer WTe2 could be very different from that of bulk samples, which may arise from the imbalance of electron and hole carriers in the samples. We shall discuss our findings in more details in light of recent progress in our experiment. This work is supported by National Natural Science Foundation of China (11374021 and 11327406); by China Ministry of Science and Technology under Contract # 2014CB920900 and 2013CB921900; and by the Young 1000-Talent Program of China.

  6. A device for in vivo measurements of quantitative ultrasound variables at the human proximal femur.

    Science.gov (United States)

    Barkmann, Reinhard; Laugier, Pascal; Moser, Urs; Dencks, Stefanie; Klausner, Michael; Padilla, Frédéric; Haïat, Guilleaume; Glüer, Claus-C

    2008-01-01

    Quantitative ultrasound (QUS) at the calcaneus has similar power as a bone mineral density (BMD)- measurement using DXA for the prediction of osteoporotic fracture risk. Ultrasound equipment is less expensive than DXA and free of ionizing radiation. As a mechanical wave, QUS has the potential of measuring different bone properties than dual X-ray absorptiometry (DXA,) which depends on X-ray attenuation and might be developed into a tool of comprehensive assessment of bone strength. However, site-specific DXA at the proximal femur shows best performance in the prediction of hip fractures. To combine the potential of QUS with measurements directly at the femur, we developed a device for in vivo QUS measurements at this site. Methods comprise ultrasound transmission through the bone, reflection from the bone surface, and backscatter from the inner trabecular structure. The complete area of the proximal femur can be scanned except at the femoral head, which interferes with the ilium. To avoid edge artifacts, a subregion of the proximal femur in the trochanteric region was selected as measurement region. First, in vivo measurements demonstrate a good signal to noise ratio and proper depiction of the proximal femur on an attenuation image. Our results demonstrate the feasibility of in vivo measurements. Further improvements can be expected by refinement of the scanning technique and data evaluation method to enhance the potential of the new method for the estimation of bone strength. PMID:18599408

  7. Development of measuring device for inner surfaces of embedded piping (Contract research)

    CERN Document Server

    Itoh, H; Tachibana, M; Yanagihara, S

    2003-01-01

    The measuring device for inner surfaces of embedded piping (MISE) was developed to evaluate low-level radiological contaminations of inner surfaces of piping. The MISE consists of a cylindrically-formed double layered type detector and a piping crawling robot, which were designed and manufactured separately. In measurements of the contaminations, an outer cylindrical detector close to the surface of piping measures beta-rays and gamma-rays and an inner cylindrical detector set after a shielding plate for shield of beta-rays measures gamma-rays. The beta-ray counting rates are derived by subtracting gamma-ray counts measured by the inner detector from gamma- and beta-ray counts measured by the outer detector. The piping crawling robot transports the cylindrically-formed double layered type detector with observing inner surfaces of piping. The detection limit for the contamination of sup 6 sup 0 Co was found to be about 0.17 Bq/cm sup 2 with measurement time of 30 seconds. It is expected that 0.2 Bq/cm sup 2 co...

  8. Investigation of doxorubicin for multidrug resistance using a fluorescent cytometric imaging system integrated onto cell culture analog devices

    Science.gov (United States)

    Kim, Donghyun; Xu, Hui; Kim, Sung J.; Shuler, Michael L.

    2004-06-01

    An integrated cytometric fluorescent imaging system is developed for characterizing chemical concentration and cellular status in microscale cell culture analog (μCCA) devices. A μCCA is used to evaluate the potential toxicity and efficacy of proposed pharmaceutical treatment of animals or humans. The imaging system, based on discrete optical components, not only provides a robust and compact tool for real-time measurements, but the modularity of the system also offers flexibility to be applicable to various μCCA structures that may be appropriate to various animal or human models. We investigate the dynamics of doxorubicin, a chemotherapeutic agent, on cultured cells in a μCCA using the integrated cytometric fluorescent imaging system. This study incorporates two uteran cancer cell lines representing a sensitive cell type and a multi-drug resistant (MDR) derivative cell line. The ultimate goal is to test the effect of MDR modulators in combination with doxorubicin to kill cancer cells while not causing undue harm to normal cells.

  9. Performance evaluation of aluminum/phosphate cell for powering small electronic devices

    Directory of Open Access Journals (Sweden)

    Gymama Slaughter

    2015-12-01

    Full Text Available We report on an innovative membrane-free aluminum/phosphate cell based on the activation of aluminum (Al as anodic material using ZnO nanocrystal in phosphate rich electrolyte that is capable of generating sufficient power to power a light-emitting diode (LED, selected as a model of a small electronic device. The energy from the cell is periodically supplied in high power bursts due to the charge and discharge cycle of the capacitor. The entire process is controlled by a switched capacitor regulator. The Al/phosphate cell was studied in neutral 100 mM phosphate buffer solution (7.4 at a temperature of 25 °C. We demonstrate that two Al/phosphate cells connected in series can generate an open circuit voltage (Voc up to 1.66 V to continuously power a LED via a switched capacitor regulator circuit. The switched capacitor regulator circuit enabled the 1 μF capacitor to store the incoming power from the cell and discharge it in a large power burst to supply the necessary drive strength required by the LED. This new Al/phosphate cell configuration is a ‘green’ alternative to the use of glucose abiotic and biofuel cells for powering ultra-low power implantable electronic devices.

  10. Research and manufacture of Rossi-α measurement device for pool thermal reactor based on virtual instrument technology

    International Nuclear Information System (INIS)

    This paper designs a set of Rossi-α measurement device for pool thermal reactor based on virtual instrument technology. This device makes PXI-6602 high-speed synchronization counter as the hardware measurement platform. By using Labview 8.5 program, the application program of data acquirement and data process analysis of the measurement device have been designed. In addition, By using Fluke-282 arbitrary waveform generator, one channel square signal which frequency and voltage are respectively defined as 200 Hz and 5 V have been produced. By using application analysis program, the pulse counter simulation test has been completed for this channel square signal. According to the test results, the measurement device reaches the measurement use requirements. (authors)

  11. Overview on the application of direct methanol fuel cell (DMFC) for portable electronic devices

    Energy Technology Data Exchange (ETDEWEB)

    Kamarudin, S.K. [Fuel Cell Institute, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor (Malaysia); Department of Chemical and Process Engineering, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor (Malaysia); Achmad, F.; Daud, W.R.W. [Fuel Cell Institute, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor (Malaysia)

    2009-08-15

    Technologically advanced human societies require specialized tools and equipment to enable their diverse and mobile activities. Portable electronic devices like laptop, PDA, handphone, etc. are now an essential tool for many people in their daily lives. The rechargeable batteries used to power the portable electronic devices could be improved upon with regards to power density, and there is a crucial need for efficient, renewable and more environmentally friendly power sources. Many researchers have shown that the direct methanol fuel cell (DMFC) is an appropriate alternative to rechargeable battery technology, although many factors must be resolved before it can be commercialized. This paper gives an overview on the possibilities for using the DMFC as portable electronic devices power source along with some views on current and future trends in DMFC development, economic analysis and presents the current problems and solutions by DMFC researchers. (author)

  12. RETRACTED: Advances in colloidal quantum dot solar cells: The depleted-heterojunction device

    KAUST Repository

    Kramer, Illan J.

    2011-08-01

    Colloidal quantum dot (CQD) photovoltaics combine low-cost solution processibility with quantum size-effect tunability to match absorption with the solar spectrum. Recent advances in CQD photovoltaics have led to 3.6% AM1.5 solar power conversion efficiencies. Here we report CQD photovoltaic devices on transparent conductive oxides and show that our devices rely on the establishment of a depletion region for field-driven charge transport and separation. The resultant depleted-heterojunction solar cells provide a 5.1% AM1.5 power conversion efficiency. The devices employ infrared-bandgap size-effect-tuned PbS colloidal quantum dots, enabling broadband harvesting of the solar spectrum. © 2010 Elsevier B.V.

  13. Advances in colloidal quantum dot solar cells: The depleted-heterojunction device

    International Nuclear Information System (INIS)

    Colloidal quantum dot (CQD) photovoltaics combine low-cost solution processibility with quantum size-effect tunability to match absorption with the solar spectrum. Recent advances in CQD photovoltaics have led to 3.6% AM1.5 solar power conversion efficiencies. Here we report CQD photovoltaic devices on transparent conductive oxides and show that our devices rely on the establishment of a depletion region for field-driven charge transport and separation. The resultant depleted-heterojunction solar cells provide a 5.1% AM1.5 power conversion efficiency. The devices employ infrared-bandgap size-effect-tuned PbS colloidal quantum dots, enabling broadband harvesting of the solar spectrum.

  14. Performance test of multi-parameter measuring devices used for quality assurance in diagnostic radiology

    International Nuclear Information System (INIS)

    Full text: Introduction: Semiconductor-based multi-parameter measuring devices (MMD) are frequently used for measurements necessary in the Quality Assurance (QA) of medical X-ray imaging devices, e.g. for acceptance and constancy tests. Such instruments are capable of measuring the X-ray tube voltage (kVp), exposure time, dose, dose rate, half-value layer (HVL) and total filtration (TF) from a single shot exposure when placed in the beam of a radiographic or mammographic X-ray device. The requirements on the performance of such instruments with respect to the parameter dose and dose rate are given in the international standard IEC 61674 and those for the non-invasive measurements of X-ray tube voltage in IEC 61676. Unfortunately, there are no standards which define requirements on the performance of measurements of the total filtration or half-value measurements. The purpose of this work was to examine the performance of MMDs with respect to their indication of the air kerma, X-ray tube voltage, half-value layer and total filtration as a function of reference radiation qualities as defined in IEC 61267 and used for studies in general radiography and mammography. The question was how do such systems comply with the manufacturer's technical specifications and with requirements of international standards. Materials and methods: Frequently used MMDs from four different manufacturers, in the paper referred to as devices A, B, C and D, were bought and examined at the X-ray facilities of the Physikalisch-Technische Bundesanstalt (PTB). Radiation qualities according to IEC 61267 and additional mammographic qualities based on W-, Mo- and Rh- anode X-ray tubes operated with constant-potential high-voltage generators were used. The X-ray tube high-voltage is measured by means of voltage dividers produced and calibrated at PTB. The photon fluence spectra of all PTB radiation qualities are measured with a high-purity germanium detector. The measured spectra were used to

  15. Integration of Rabbit Adipose Derived Mesenchymal Stem Cells to Hydroxyapatite Burr Hole Button Device for Bone Interface Regeneration

    Science.gov (United States)

    Gayathri, Viswanathan; Harikrishnan, Varma; Mohanan, Parayanthala Valappil

    2016-01-01

    Adipose Derived Mesenchymal Stem Cells, multipotent stem cells isolated from adipose tissue, present close resemblance to the natural in vivo milieu and microenvironment of bone tissue and hence widely used for in bone tissue engineering applications. The present study evaluates the compatibility of tissue engineered hydroxyapatite burr hole button device (HAP-BHB) seeded with Rabbit Adipose Derived Mesenchymal Stem Cells (ADMSCs). Cytotoxicity, oxidative stress response, apoptotic behavior, attachment, and adherence of adipose MSC seeded on the device were evaluated by scanning electron and confocal microscopy. The results of the MTT (3-(4,5-dimethylthiazol)-2,5-diphenyl tetrazolium bromide) assay indicated that powdered device material was noncytotoxic up to 0.5 g/mL on cultured cells. It was also observed that oxidative stress related reactive oxygen species production and apoptosis on cell seeded device were similar to those of control (cells alone) except in 3-day period which showed increased reactive oxygen species generation. Further scanning electron and confocal microscopy indicated a uniform attachment of cells and viability up to 200 μm deep inside the device, respectively. Based on the results, it can be concluded that the in-house developed HAP-BHB device seeded with ADMSCs is nontoxic/safe compatible device for biomedical application and an attractive tissue engineered device for calvarial defect regeneration. PMID:26880922

  16. Reversible energy storage on a fuel cell-supercapacitor hybrid device

    Energy Technology Data Exchange (ETDEWEB)

    Zerpa Unda, Jesus Enrique

    2011-02-18

    A new concept of energy storage based on hydrogen which operates reversibly near ambient conditions and without important energy losses is investigated. This concept involves the hybridization between a proton exchange membrane fuel cell and a supercapacitor. The main idea consists in the electrochemical splitting of hydrogen at a PEM fuel cell-type electrode into protons and electrons and then in the storage of these two species separately in the electrical double layer of a supercapacitor-type electrode which is made of electrically conductive large-surface area carbon materials. The investigation of this concept was performed first using a two-electrode fuel cell-supercapacitor hybrid device. A three-electrode hybrid cell was used to explore the application of this concept as a hydrogen buffer integrated inside a PEM fuel cell to be used in case of peak power demand. (orig.)

  17. Biased decoy-state measurement-device-independent quantum cryptographic conferencing with finite resources.

    Science.gov (United States)

    Chen, RuiKe; Bao, WanSu; Zhou, Chun; Li, Hongwei; Wang, Yang; Bao, HaiZe

    2016-03-21

    In recent years, a large quantity of work have been done to narrow the gap between theory and practice in quantum key distribution (QKD). However, most of them are focus on two-party protocols. Very recently, Yao Fu et al proposed a measurement-device-independent quantum cryptographic conferencing (MDI-QCC) protocol and proved its security in the limit of infinitely long keys. As a step towards practical application for MDI-QCC, we design a biased decoy-state measurement-device-independent quantum cryptographic conferencing protocol and analyze the performance of the protocol in both the finite-key and infinite-key regime. From numerical simulations, we show that our decoy-state analysis is tighter than Yao Fu et al. That is, we can achieve the nonzero asymptotic secret key rate in long distance with approximate to 200km and we also demonstrate that with a finite size of data (say 1011 to 1013 signals) it is possible to perform secure MDI-QCC over reasonable distances. PMID:27136849

  18. Zeff profile measurement system with an optimized Czerny-Turner visible spectrometer in large helical device

    International Nuclear Information System (INIS)

    Zeff measurement system using a visible spectrometer has been newly designed and constructed instead of an old interference filter system to eliminate line emissions from the signal and to measure the Zeff value in low-density plasmas. The system consists of the Czerny-Turner-type spectrometer with a charge-coupled device camera and 44 optical fibers vertical array. The spectrometer is equipped with an additional toroidal mirror for further reduction in the astigmatism in addition to a flat and two spherical mirrors and three gratings (110, 120, and 1200 grooves/mm) with 30 cm focal length. The images from 44 optical fibers can be detected without astigmatism in a wavelength range of 200-900 nm. Combination of the optical fiber (core diameter: 100 μm) with the lens (focal length: 30 mm) provides spatial resolution of 30 mm at the plasma center. Results clearly indicate a very good focus image of the fiber and suggest the absence of the cross-talk between adjacent fiber images. Absolute intensity calibration has been done using a standard tungsten lamp to analyze the Zeff value. The bremsstrahlung profile and resultant Zeff profile have been obtained after Abel inversion of the signals observed in large helical device plasmas with elliptical poloidal cross section.

  19. Automatic device for measuring β-emitting sources: P.A.P.A. β-meters

    International Nuclear Information System (INIS)

    The apparatus described is designed for measuring β-emitting elements by the absorption method; it is suitable for carrying out a large number of routine analyses. A mechanical device pushes an aluminium absorption set automatically between the source and the detector; the movement is programmed for cutting on and off by a transistorized electronic unit, with printing out and punching of the results on tape; then this can be mathematically processed by a computer (tracing of absorption spectra, extrapolation and calculation of the activity). The detector is either a β-probe or a proportional counter with a specially designed loop. For routine measurements, the accuracy obtained, with all corrections made, is from 5 to 8 per cent; the reproducibility is about 2 per cent. (authors)

  20. DANCE device for measurement of (n, γ) reactions on radioactive species

    International Nuclear Information System (INIS)

    DANCE (Device for Advanced Neutron Capture Experiments) is a 4π 162 element BaF2 array under development at Los Alamos National Laboratory. It is designed to provide high granularity, fast timing and high photon detection efficiency. It will be located at the Los Alamos Neutron Scattering Center where neutrons are produced using 800 MeV proton induced spallation reactions on heavy element production targets. Using the pulsed high neutron fluence available at this facility combined with time of flight techniques it will be possible to make neutron capture measurements in the neutron energy range from eV to 100's keV on rate and radioactive target material at the milligram and below level. These measurements will provide critically needed data for the interpretation of the astrophysical s-process 'branching point' nuclei as well as information for reactions needed in understanding transmutation processes of radioactive species. (author)

  1. DANCE: Device for Measurement of (n.g.) Reactions on radioactive Species

    International Nuclear Information System (INIS)

    DANCE (Device for Advanced Neutron Capture Experiments) is a 4π 162 element BaF2 array under development at Los Alamos National Laboratory. It is designed to provide high granularity, fast timing and high photon detection efficiency. It will be located at the Los Alamos Neutron Scattering Center where neutrons are produced using 800 MeV proton induced spallation reactions on heavy element production targets. Using the pulsed high neutron fluence available at this facility combined with time of flight techniques it will be possible to make neutron capture measurements in the neutron energy range from eV to 100's of keV on rare and radioactive target material at the milligram and below level. These measurements will provide critically needed data for the interpretation of the astrophysical s-process 'branching point' nuclei as well as information for reactions needed in understanding transmutation processes of radioactive species.

  2. DANCE : Device for Measurement of (n.g.) Reactions on radioactive Species /

    Energy Technology Data Exchange (ETDEWEB)

    Chamberlin, E. P. (Edwin P.); Dragowsky, M. (Michael); Fowler, Malcolm M.; Miller, G. G. (Geoffrey G.); Palmer, P. D. (Phillip D.); Pangualt, L. N. (Laurence N.); Rundberg, R. S. (Robert S.); Haight, Robert C.; Seabury, E. H. (Edward H.); Ullmann, J. L. (John L.); Strottman, D. D. (Daniel D.); Heil, M. (Michael); Kaeppeler, F. (Franz K.); Reifarth, R. (Rene); Wisshak, K.; Wilhelmy, J. B. (Jerry B.)

    2001-01-01

    DANCE (Device for Advanced Neutron Capture Experiments) is a 4{pi} 162 element BaF{sub 2} array under development at Los Alamos National Laboratory. It is designed to provide high granularity, fast timing and high photon detection efficiency. It will be located at the Los Alamos Neutron Scattering Center where neutrons are produced using 800 MeV proton induced spallation reactions on heavy element production targets. Using the pulsed high neutron fluence available at this facility combined with time of flight techniques it will be possible to make neutron capture measurements in the neutron energy range from eV to 100's of keV on rare and radioactive target material at the milligram and below level. These measurements will provide critically needed data for the interpretation of the astrophysical s-process 'branching point' nuclei as well as information for reactions needed in understanding transmutation processes of radioactive species.

  3. DANCE device for measurement of (n, {gamma}) reactions on radioactive species

    Energy Technology Data Exchange (ETDEWEB)

    Wilhelmy, J.B.; Chamberlin, E.P.; Dragowsky, M.R. [Los Alamos National Laboratory, Los Alamos, New Mexico (US)] [and others

    2002-08-01

    DANCE (Device for Advanced Neutron Capture Experiments) is a 4{pi} 162 element BaF{sub 2} array under development at Los Alamos National Laboratory. It is designed to provide high granularity, fast timing and high photon detection efficiency. It will be located at the Los Alamos Neutron Scattering Center where neutrons are produced using 800 MeV proton induced spallation reactions on heavy element production targets. Using the pulsed high neutron fluence available at this facility combined with time of flight techniques it will be possible to make neutron capture measurements in the neutron energy range from eV to 100's keV on rate and radioactive target material at the milligram and below level. These measurements will provide critically needed data for the interpretation of the astrophysical s-process 'branching point' nuclei as well as information for reactions needed in understanding transmutation processes of radioactive species. (author)

  4. Piezoelectric actuator-based cell microstretch device with real-time imaging capability

    Directory of Open Access Journals (Sweden)

    Shinji Deguchi

    2015-06-01

    Full Text Available Cellular response to physical stretch has been extensively studied as a regulator of various physiological functions. For live cell microscopy combined with stretch experiments, cells are typically seeded on an extensible elastomer sheet. In this case, the position of the cells of interest tends to shift out of the field of view upon stretch, making real-time imaging of identical cells difficult. To circumvent this situation, here we describe a robust methodology in which these cell shifts are minimized. Cells are plated in a custom-designed stretch chamber with an elastomer sheet of a small cell culture area. The cell-supporting chamber is stretched on an inverted microscope by using a piezoelectric actuator that provides small, but precisely controlled displacements. Even under this small displacement within the filed of view, our device allows the cells to undergo physiologically relevant levels of stretch. Identical cells can thus be continuously observed during stretching, thereby potentially enabling imaging of stretch-triggered fast dynamics.

  5. Atomistic simulations of electrochemical metallization cells: mechanisms of ultra-fast resistance switching in nanoscale devices

    Science.gov (United States)

    Onofrio, Nicolas; Guzman, David; Strachan, Alejandro

    2016-07-01

    We describe a new method that enables reactive molecular dynamics (MD) simulations of electrochemical processes and apply it to study electrochemical metallization cells (ECMs). The model, called EChemDID, extends the charge equilibration method to capture the effect of external electrochemical potential on partial atomic charges and describes its equilibration over connected metallic structures, on-the-fly, during the MD simulation. We use EChemDID to simulate resistance switching in nanoscale ECMs; these devices consist of an electroactive metal separated from an inactive electrode by an insulator and can be reversibly switched to a low-resistance state by the electrochemical formation of a conducting filament between electrodes. Our structures use Cu as the active electrode and SiO2 as the dielectric and have dimensions at the foreseen limit of scalability of the technology, with a dielectric thickness of approximately 1 nm. We explore the effect of device geometry on switching timescales and find that nanowires with an electroactive shell, where ions migrate towards a smaller inactive electrode core, result in faster switching than planar devices. We observe significant device-to-device variability in switching timescales and intermittent switching for these nanoscale devices. To characterize the evolution in the electronic structure of the dielectric as dissolved metallic ions switch the device, we perform density functional theory calculations on structures obtained from an EChemDID MD simulation. These results confirm the appearance of states around the Fermi energy as the metallic filament bridges the electrodes and show that the metallic ions and not defects in the dielectric contribute to the majority of those states.

  6. Atomistic simulations of electrochemical metallization cells: mechanisms of ultra-fast resistance switching in nanoscale devices.

    Science.gov (United States)

    Onofrio, Nicolas; Guzman, David; Strachan, Alejandro

    2016-08-01

    We describe a new method that enables reactive molecular dynamics (MD) simulations of electrochemical processes and apply it to study electrochemical metallization cells (ECMs). The model, called EChemDID, extends the charge equilibration method to capture the effect of external electrochemical potential on partial atomic charges and describes its equilibration over connected metallic structures, on-the-fly, during the MD simulation. We use EChemDID to simulate resistance switching in nanoscale ECMs; these devices consist of an electroactive metal separated from an inactive electrode by an insulator and can be reversibly switched to a low-resistance state by the electrochemical formation of a conducting filament between electrodes. Our structures use Cu as the active electrode and SiO2 as the dielectric and have dimensions at the foreseen limit of scalability of the technology, with a dielectric thickness of approximately 1 nm. We explore the effect of device geometry on switching timescales and find that nanowires with an electroactive shell, where ions migrate towards a smaller inactive electrode core, result in faster switching than planar devices. We observe significant device-to-device variability in switching timescales and intermittent switching for these nanoscale devices. To characterize the evolution in the electronic structure of the dielectric as dissolved metallic ions switch the device, we perform density functional theory calculations on structures obtained from an EChemDID MD simulation. These results confirm the appearance of states around the Fermi energy as the metallic filament bridges the electrodes and show that the metallic ions and not defects in the dielectric contribute to the majority of those states. PMID:27218609

  7. Simple field device for measurement of dimethyl sulfide and dimethylsulfoniopropionate in natural waters, based on vapor generation and chemiluminescence detection.

    Science.gov (United States)

    Nagahata, Takanori; Kajiwara, Hidetaka; Ohira, Shin-Ichi; Toda, Kei

    2013-05-01

    A small, simple device was developed for trace analysis of dimethyl sulfide (DMS) and dimethylsulfoniopropionate (DMSP) in natural waters. These compounds are known to be the major sources of cloud condensation nuclei in the oceanic atmosphere and ideally should be measured onsite because of their volatility and instability. First, chemical and physical vapor generations were examined, and simple pressurizing by injection of 30 mL of air using a syringe was adopted. Pressurized headspace air above a 10 mL water sample was introduced to a detection cell as a result of the pressure differential and mixed with ozone to induce chemiluminescence. Although the measurement procedure was simple, the method was very sensitive: sharp peaks appeared within seconds for nanomolar levels of DMS, and the limit of detection was 0.02 nmol L(-1) (1 ng L(-1)). Although interference from methanethiol was significant, this was successfully addressed by adding a small amount of Cd(2+) before DMS vapor generation. DMSP was also measured after hydrolysis to DMS, as previously reported. Pond water and seawater samples were analyzed, and DMS was found in both types of sample, whereas DMSP was observed only in seawater. The DMS/DMSP data obtained using the developed method were compared with data obtained by purge/trap and gas chromatography-mass spectrometry, and the data from the two methods agreed, with good correlation (R(2) = 0.9956). The developed device is inexpensive, light (5 kg), simple to use, can be applied in the field, and is sensitive enough for fresh- and seawater analysis. PMID:23551252

  8. Microfluidic Device for the Measurement of Amino Acid Secretion Dynamics from Murine and Human Islets of Langerhans.

    Science.gov (United States)

    Wang, Xue; Yi, Lian; Roper, Michael G

    2016-03-15

    Islets of Langerhans are the regulators of in vivo blood glucose levels through the secretion of endocrine hormones. Amino acids, released from various cells within islets or from intrapancreatic neurons, are hypothesized to further adjust hormone secretions. In contrast to the well-accepted mechanism of glucose-stimulated insulin secretion, several questions remain as to the function of amino acids in the regulation of hormone release from islets. To understand the autocrine and paracrine roles that amino acids play in islet physiology, a microfluidic system was developed to perform online monitoring of the secretion profiles of amino acids from 2-5 islets. The device contained an islet chamber with the ability to perfuse stimulants and an amino acid measurement system with derivatization and electrophoretic separation integrated on a single microchip. The setup was optimized to allow -15 kV to be applied to the device for high efficiency and rapid separations of derivatized amino acids. The compositions of the derivatization and separation buffers were optimized to prevent precipitations in the channels, which allowed continuous monitoring of secretion for over 2 h. With this method, 10 amino acids were resolved with limits of detection ranging from 1 to 20 nM. When murine islets were perfused with 3 mM glucose, the secretion rates of 9 amino acids were measured and ranged from 30 to 400 fmol islet(-1) min(-1). As the glucose concentration was increased to 20 mM, the dynamic changes of amino acids were monitored. The biological relevance of the amino acid secretions was verified using 2,4-dinitrophenol as an inhibitor of the proton motive force. The microfluidic system was also used to measure dynamic changes of amino acid release from human islets, which showed different release profiles compared to their murine counterparts. PMID:26891222

  9. Out-of-focus effects on microscale schlieren measurements of mass transport in a microfluidic device

    Science.gov (United States)

    Chen, Shao-Tuan; Sun, Chen-li

    2016-08-01

    The microscale schlieren technique provides a means for a non-invasive, full-field measurement for mixing microfluidics with excellent sensitivity and resolution. Nevertheless, an out-of-focus effect due to microscopic optics may lead to undesirable errors in quantifying the gradient information at high degrees of magnification. If the channel in the microfluidic device under study is too deep, light deflection caused by inhomogeneity located far from the focal plane may contributes little to the intensity change on the image plane. To address this issue, we propose the use of a weighting function that approximates a Gaussian profile with an optical-system-dependable width. We assume that the resultant intensity change is proportional to a weighted sum of the gradient across the channel depth and acquire micro-schlieren images of fluid mixing in a T-junction microchannel at various positions along the optical axis. For each objective, the width of the weighting function is then determined iteratively by curve fitting the ratio of changes in grayscale readouts for out-of-focus and focus micro-schlieren images. The standard deviation in the Gaussian distribution facilitates the quantification of the out-of-focus effect. In addition, we measure the sensitivities of a microscale schlieren system equipped with different objectives and compare the values to the model. Despite its better resolution, we find that an objective with higher magnification suffers from a more severe out-of-focus effect and a loss of sensitivity. Equations are proposed for estimations of the standard deviation and the sensitivity of microscale schlieren measurements. The outcome will facilitate the selection of proper microchannel depths for various microscale schlieren systems or vice versa, thus improving the precision of micro-schlieren measurements in microfluidic devices.

  10. Measurement of uranium and plutonium content in a fuel assembly using the RPI spent fuel assay device

    International Nuclear Information System (INIS)

    In this paper we report measurements of the significant parameters, the sensitivities of the slowing-down-time assay device to the fissile contents of a boiling water reactor (BWR) assembly mock-up of fresh fuel

  11. Comparison of sound speed measurements on two different ultrasound tomography devices

    Science.gov (United States)

    Sak, Mark; Duric, Neb; Littrup, Peter; Bey-Knight, Lisa; Sherman, Mark; Gierach, Gretchen; Malyarenko, Antonina

    2014-03-01

    Ultrasound tomography (UST) employs sound waves to produce three-dimensional images of breast tissue and precisely measures the attenuation of sound speed secondary to breast tissue composition. High breast density is a strong breast cancer risk factor and sound speed is directly proportional to breast density. UST provides a quantitative measure of breast density based on three-dimensional imaging without compression, thereby overcoming the shortcomings of many other imaging modalities. The quantitative nature of the UST breast density measures are tied to an external standard, so sound speed measurement in breast tissue should be independent of specific hardware. The work presented here compares breast sound speed measurement obtained with two different UST devices. The Computerized Ultrasound Risk Evaluation (CURE) system located at the Karmanos Cancer Institute in Detroit, Michigan was recently replaced with the SoftVue ultrasound tomographic device. Ongoing clinical trials have used images generated from both sets of hardware, so maintaining consistency in sound speed measurements is important. During an overlap period when both systems were in the same exam room, a total of 12 patients had one or both of their breasts imaged on both systems on the same day. There were 22 sound speed scans analyzed from each system and the average breast sound speeds were compared. Images were either reconstructed using saved raw data (for both CURE and SoftVue) or were created during the image acquisition (saved in DICOM format for SoftVue scans only). The sound speed measurements from each system were strongly and positively correlated with each other. The average difference in sound speed between the two sets of data was on the order of 1-2 m/s and this result was not statistically significant. The only sets of images that showed a statistical difference were the DICOM images created during the SoftVue scan compared to the SoftVue images reconstructed from the raw data

  12. Ultrasonic device for real-time sewage velocity and suspended particles concentration measurements.

    Science.gov (United States)

    Abda, F; Azbaid, A; Ensminger, D; Fischer, S; François, P; Schmitt, P; Pallarès, A

    2009-01-01

    In the frame of a technological research and innovation network in water and environment technologies (RITEAU, Réseau de Recherche et d'Innovation Technologique Eau et Environnement), our research group, in collaboration with industrial partners and other research institutions, has been in charge of the development of a suitable flowmeter: an ultrasonic device measuring simultaneously the water flow and the concentration of size classes of suspended particles. Working on the pulsed ultrasound principle, our multi-frequency device (1 to 14 MHz) allows flow velocity and water height measurement and estimation of suspended solids concentration. Velocity measurements rely on the coherent Doppler principle. A self developed frequency estimator, so called Spectral Identification method, was used and compared to the classical Pulse-Pair method. Several measurements campaigns on one wastewater collector of the French city of Strasbourg gave very satisfactory results and showed smaller standard deviation values for the Doppler frequency extracted by the Spectral Identification method. A specific algorithm was also developed for the water height measurements. It relies on the water surface acoustic impedance rupture and its peak localisation and behaviour in the collected backscattering data. This algorithm was positively tested on long time measurements on the same wastewater collector. A large part of the article is devoted to the measurements of the suspended solids concentrations. Our data analysis consists in the adaptation of the well described acoustic behaviour of sand to the behaviour of wastewater particles. Both acoustic attenuation and acoustic backscattering data over multiple frequencies are analyzed for the extrapolation of size classes and respective concentrations. Under dry weather conditions, the massic backscattering coefficient and the overall size distribution showed similar evolution whatever the measurement site was and were suggesting a global

  13. Cobalt-Based Electrolytes for Dye-Sensitized Solar Cells: Recent Advances towards Stable Devices

    Directory of Open Access Journals (Sweden)

    Federico Bella

    2016-05-01

    Full Text Available Redox mediators based on cobalt complexes allowed dye-sensitized solar cells (DSCs to achieve efficiencies exceeding 14%, thus challenging the emerging class of perovskite solar cells. Unfortunately, cobalt-based electrolytes demonstrate much lower long-term stability trends if compared to the traditional iodide/triiodide redox couple. In view of the large-scale commercialization of cobalt-based DSCs, the scientific community has recently proposed various approaches and materials to increase the stability of these devices, which comprise gelling agents, crosslinked polymeric matrices and mixtures of solvents (including water. This review summarizes the most significant advances recently focused towards this direction, also suggesting some intriguing way to fabricate third-generation cobalt-based photoelectrochemical devices stable over time.

  14. Standard practices for verification of displacement measuring systems and devices used in material testing machines

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2005-01-01

    1.1 These practices cover procedures and requirements for the calibration and verification of displacement measuring systems by means of standard calibration devices for static and quasi-static testing machines. This practice is not intended to be complete purchase specifications for testing machines or displacement measuring systems. Displacement measuring systems are not intended to be used for the determination of strain. See Practice E83. 1.2 These procedures apply to the verification of the displacement measuring systems associated with the testing machine, such as a scale, dial, marked or unmarked recorder chart, digital display, etc. In all cases the buyer/owner/user must designate the displacement-measuring system(s) to be verified. 1.3 The values stated in either SI units or inch-pound units are to be regarded separately as standard. The values stated in each system may not be exact equivalents; therefore, each system shall be used independently of the other. Combining values from the two systems m...

  15. An experimental device for measurement of gas permeation in solid matrices

    International Nuclear Information System (INIS)

    The inventory in and the permeation through fusion reactor structures of hydrogen and its isotopes play an important role in the machine operation, evolution of material properties, and safety. An experimental and research activity for the determination of permeability (and derived parameters) of gases in solid matrices is described. It uses a gas permeation method, that basically consists in the measure of the time evolution of the gas pressure in a chamber in which vacuum has been previously made (downstream volume). This chamber is separated from another one, full of the gas in exam (upstream volume), by means of a membrane of the material under study. The experimental installation is described. The first stage of the experimental activity has dealt with the set-up of the device, the volume calibration, and the definition of the parameters range for which the installation can give reliable measurements. The subsequent stage of the activity has consisted in the measurement of the permeability, and then of the diffusion coefficient, of nitrogen in some materials at room temperature. Concurrently with the experimental activity, a model has been set-up and implemented in a computer code: this code permits to evaluate the time evolution of the pressure in the downstream chamber. With this code, using the measured parameters, the time evolution of the pressure experimentally measured has been satisfactorily reproduced. (author)

  16. Power loss measurement of implantable wireless power transfer components using a Peltier device balance calorimeter

    International Nuclear Information System (INIS)

    Determining heat losses in power transfer components operating at high frequencies for implantable inductive power transfer systems is important for assessing whether the heat dissipated by the component is acceptable for implantation and medical use. However, this is a challenge at high frequencies and voltages due to limitations in electronic instrumentation. Calorimetric methods of power measurement are immune to the effects of high frequencies and voltages; hence, the measurement is independent of the electrical characteristics of the system. Calorimeters have been widely used to measure the losses of high power electrical components (>50 W), however it is more difficult to perform on low power components. This paper presents a novel power measurement method for components dissipating anywhere between 0.2 W and 1 W of power based on a heat balance calorimeter that uses a Peltier device as a balance sensor. The proposed balance calorimeter has a single test accuracy of ±0.042 W. The experimental results revealed that there was up to 35% difference between the power measurements obtained with electrical methods and the proposed calorimeter. (paper)

  17. A mobile measuring device for the determination of radionuclides in surface waters by in-situ gamma-ray spectroscopy

    International Nuclear Information System (INIS)

    A mobile measuring device to determine radionuclides in surface waters by in-situ gamma-ray spectrometry is presented. Important data (full width at half maximum (FWHM), calibration factors and photopeak efficiency) are reported. The detection limits obtained under realistic conditions demonstrate that this mobile measuring device is appropriate for the detection and evaluation of radionuclides in surface waters in the event of accidents as well as for performing methodical studies using selected radiotracers. (orig.)

  18. Experimental device for measurement of dielectronic recombination cross section of C3+: method of confluent beam method

    International Nuclear Information System (INIS)

    Description of an instrumental device allowing dielectronic recombination cross section measurement is presented. Recombination of C3+ for high quantum number is studied. This device, using the confluent beam method, entailed the development of an electron gun producing weakly divergent beam. A detector of highly excited ion allowing a quick and accurate measurement of ion beam energy is described in detail. Beam-residual gas interaction mechanisms are studied and instrumental incertitudes are calculated

  19. Cell Selection Game for Densely-Deployed Sensor and Mobile Devices In 5G Networks Integrating Heterogeneous Cells and the Internet of Things

    OpenAIRE

    Lusheng Wang; Yamei Wang; Zhizhong Ding; Xiumin Wang

    2015-01-01

    With the rapid development of wireless networking technologies, the Internet of Things and heterogeneous cellular networks (HCNs) tend to be integrated to form a promising wireless network paradigm for 5G. Hyper-dense sensor and mobile devices will be deployed under the coverage of heterogeneous cells, so that each of them could freely select any available cell covering it and compete for resource with others selecting the same cell, forming a cell selection (CS) game between these devices. S...

  20. MELIFT - A new device for accurate measurements in a snow rich environment

    Science.gov (United States)

    Dorninger, M.

    2012-04-01

    A deep snow pack, remote locations, no external power supply and very low temperatures are often the main ingredients when it comes to the deployment of meteorological stations in mountainous terrain. The accurate position of the sensor related to the snow surface is normally not known. A new device called METLIFT overcomes the problems. WMO recommends a height between 1.2 m and 2 m above ground level for the measurement of air temperature and humidity. The height above ground level is specified to take care of the possible strong vertical temperature and humidity gradients at the lowest layers in the atmosphere. Especially in snow rich and remote locations it may be hardly possible to follow this advice. Therefore most of the meteorological stations in mountainous terrain are situated at mountain tops where strong winds will blow off the snow or in valleys where a daily inspection of the sensors is possible. In other unpopulated mountainous areas, e.g. basins, plateaus, the distance of the sensor to the snow surface is not known or the sensor will be snow-covered. A new device was developed to guarantee the sensor height above surface within the WMO limits in harsh and remote environments. An ultrasonic snow height sensor measures the distance to the snow surface. If it exceeds certain limits due to snow accumulation or snow melt the lift adapts its height accordingly. The prototype of METLIFT has been installed in Lower Austria at an altitude of 1000m. The lift is 6 m high and can pull out for another 4 m. Sensor arms are mounted every meter to allow the connection of additional sensors or to measure a profile of a certain parameter of the lowest 5 m above surface. Sensors can be added easily since cable wiring is provided to each sensor arm. Horizontal winds are measured at 7 m height above surface. METLIFT is independent of external power supply. Three lead gel accumulators recharged by three solar panels provide the energy necessary for the sensors, the data